# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- COX6B PF02297.17 KFO94843.1 - 3.6e-14 52.7 4.3 4.5e-14 52.4 4.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb zf-C2H2_11 PF16622.5 KFO94844.1 - 1.8e-06 27.6 7.9 0.0031 17.2 1.2 2.1 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2 PF00096.26 KFO94844.1 - 2.3e-05 24.6 13.6 0.018 15.5 5.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type XPA_N PF01286.18 KFO94844.1 - 5.7e-05 23.1 4.9 0.047 13.7 0.1 2.2 2 0 0 2 2 2 2 XPA protein N-terminal zf-C2H2_4 PF13894.6 KFO94844.1 - 7.6e-05 23.2 11.0 0.04 14.8 4.3 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFO94844.1 - 7.9e-05 22.7 2.5 0.045 13.9 0.1 2.1 2 0 0 2 2 2 2 Zinc ribbon domain zf_UBZ PF18439.1 KFO94844.1 - 0.00017 21.1 2.6 0.071 12.7 0.2 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-trcl PF13451.6 KFO94844.1 - 0.00024 20.9 4.3 0.051 13.5 1.1 2.1 2 0 0 2 2 2 2 Probable zinc-ribbon domain DUF2256 PF10013.9 KFO94844.1 - 0.0017 18.4 3.6 0.75 10.0 0.7 2.4 1 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2256) Ribosomal_L31 PF01197.18 KFO94844.1 - 0.0021 18.3 1.4 0.45 10.8 1.4 2.2 1 1 0 1 1 1 1 Ribosomal protein L31 zf-H2C2_2 PF13465.6 KFO94844.1 - 0.0043 17.4 3.1 0.0043 17.4 3.1 3.4 3 1 0 3 3 3 1 Zinc-finger double domain TFIIS_C PF01096.18 KFO94844.1 - 0.012 15.5 3.9 0.38 10.6 0.2 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DZR PF12773.7 KFO94844.1 - 0.012 15.6 0.8 0.019 15.0 0.8 1.4 1 1 0 1 1 1 0 Double zinc ribbon DNA_RNApol_7kD PF03604.13 KFO94844.1 - 0.012 15.2 1.1 1.8 8.3 0.1 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit HalOD2 PF18547.1 KFO94844.1 - 0.016 15.1 1.7 1.1 9.2 0.1 2.2 2 0 0 2 2 2 0 Halobacterial output domain 2 FYVE PF01363.21 KFO94844.1 - 0.032 14.4 6.2 0.33 11.1 0.2 2.0 1 1 1 2 2 2 0 FYVE zinc finger zf-LYAR PF08790.11 KFO94844.1 - 0.035 14.0 8.6 0.085 12.8 1.4 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger YhfH PF14149.6 KFO94844.1 - 0.039 13.9 5.3 2 8.5 0.2 2.3 2 1 0 2 2 2 0 YhfH-like protein Ephrin_rec_like PF07699.13 KFO94844.1 - 0.048 13.4 2.8 0.78 9.5 0.1 2.2 2 0 0 2 2 2 0 Putative ephrin-receptor like zf-UBP PF02148.19 KFO94844.1 - 0.049 14.0 4.1 0.13 12.7 4.1 1.7 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zinc-ribbons_6 PF07191.12 KFO94844.1 - 0.056 13.4 1.9 0.075 13.0 1.9 1.3 1 0 0 1 1 1 0 zinc-ribbons zf-C2H2_jaz PF12171.8 KFO94844.1 - 0.098 13.0 6.9 1.5 9.2 0.1 2.9 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding LIM PF00412.22 KFO94844.1 - 0.12 12.7 4.7 4.5 7.6 4.7 2.2 1 1 0 1 1 1 0 LIM domain Zn_ribbon_SprT PF17283.2 KFO94844.1 - 0.13 12.2 4.1 0.67 9.9 0.2 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain TF_Zn_Ribbon PF08271.12 KFO94844.1 - 0.13 11.8 2.7 2.8 7.5 0.1 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding HNH PF01844.23 KFO94844.1 - 0.23 11.7 8.7 3.3 7.9 3.0 2.1 2 0 0 2 2 2 0 HNH endonuclease FYDLN_acid PF09538.10 KFO94844.1 - 0.24 12.1 0.4 1.8 9.3 0.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) HypA PF01155.19 KFO94844.1 - 0.37 10.8 3.1 0.85 9.7 3.0 1.6 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_6 PF13912.6 KFO94844.1 - 2 8.5 17.8 0.46 10.5 0.8 2.7 3 0 0 3 3 2 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KFO94844.1 - 2.7 7.7 7.0 0.88 9.3 0.8 2.1 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain 7tm_4 PF13853.6 KFO94845.1 - 3.5e-10 40.1 0.3 4e-10 39.9 0.3 1.0 1 0 0 1 1 1 1 Olfactory receptor RVT_1 PF00078.27 KFO94846.1 - 1e-15 57.9 0.0 1.4e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 KFO94846.1 - 1.7e-14 53.4 0.4 2.6e-14 52.8 0.4 1.3 1 0 0 1 1 1 1 Reverse transcriptase thumb domain zf-C2H2 PF00096.26 KFO94847.1 - 6.5e-11 42.1 9.3 3.4e-07 30.4 0.4 2.3 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO94847.1 - 2.6e-07 30.8 0.4 2.6e-07 30.8 0.4 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFO94847.1 - 2.9e-07 30.8 7.4 2.2e-05 24.9 0.3 2.3 2 1 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 KFO94847.1 - 0.017 15.4 0.5 0.42 10.9 0.2 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 KFO94847.1 - 0.033 14.0 0.1 0.44 10.4 0.1 1.9 1 1 1 2 2 2 0 GAGA factor zf-C2H2_jaz PF12171.8 KFO94847.1 - 0.039 14.3 1.5 0.075 13.3 0.0 2.0 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFO94847.1 - 0.091 12.5 0.0 0.091 12.5 0.0 2.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf_UBZ PF18439.1 KFO94847.1 - 0.097 12.3 0.6 0.18 11.4 0.1 1.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_9 PF14369.6 KFO94847.1 - 0.62 10.4 2.8 20 5.5 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon zf-H2C2_2 PF13465.6 KFO94848.1 - 6.7e-09 35.8 9.0 4.2e-08 33.2 0.7 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KFO94848.1 - 9.3e-07 29.0 7.3 0.012 16.1 0.2 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO94848.1 - 6.7e-05 23.4 7.8 0.051 14.4 2.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-trcl PF13451.6 KFO94848.1 - 0.00057 19.7 3.5 0.032 14.1 0.4 2.5 1 1 1 2 2 2 2 Probable zinc-ribbon domain zf_UBZ PF18439.1 KFO94848.1 - 0.002 17.7 1.5 0.13 11.8 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger Zn_Tnp_IS1595 PF12760.7 KFO94848.1 - 0.0041 17.1 1.7 0.008 16.1 1.6 1.6 1 1 0 1 1 1 1 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 KFO94848.1 - 0.0042 17.2 3.4 0.14 12.3 2.7 2.2 1 1 1 2 2 2 2 Zinc ribbon domain IBR PF01485.21 KFO94848.1 - 0.0052 17.0 4.6 0.0066 16.7 4.6 1.2 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain zinc_ribbon_4 PF13717.6 KFO94848.1 - 0.0065 16.4 1.1 0.061 13.3 1.1 2.1 1 1 0 1 1 1 1 zinc-ribbon domain LIM PF00412.22 KFO94848.1 - 0.0083 16.3 0.6 0.013 15.7 0.6 1.4 1 1 0 1 1 1 1 LIM domain DUF2256 PF10013.9 KFO94848.1 - 0.009 16.1 6.9 0.62 10.2 0.5 2.4 2 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2256) YacG PF03884.14 KFO94848.1 - 0.011 15.5 2.1 2.5 7.9 0.5 2.2 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG zinc-ribbons_6 PF07191.12 KFO94848.1 - 0.014 15.4 0.8 0.023 14.7 0.8 1.4 1 1 0 1 1 1 0 zinc-ribbons zf-Di19 PF05605.12 KFO94848.1 - 0.017 15.4 0.3 0.04 14.2 0.3 1.6 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding ADK_lid PF05191.14 KFO94848.1 - 0.02 14.8 0.1 0.051 13.6 0.1 1.7 1 1 1 2 2 2 0 Adenylate kinase, active site lid zf-C2H2_6 PF13912.6 KFO94848.1 - 0.023 14.7 4.2 0.082 12.9 0.6 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger CpXC PF14353.6 KFO94848.1 - 0.023 14.7 0.2 0.57 10.2 0.2 2.0 1 1 0 1 1 1 0 CpXC protein zinc_ribbon_5 PF13719.6 KFO94848.1 - 0.025 14.3 2.6 0.13 12.0 2.6 2.0 1 1 0 1 1 1 0 zinc-ribbon domain DUF2321 PF10083.9 KFO94848.1 - 0.026 14.1 1.0 0.17 11.5 1.0 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) YhfH PF14149.6 KFO94848.1 - 0.027 14.4 2.0 1.1 9.2 0.1 2.3 2 0 0 2 2 2 0 YhfH-like protein FYVE PF01363.21 KFO94848.1 - 0.06 13.5 3.2 0.19 11.9 1.9 1.9 1 1 1 2 2 2 0 FYVE zinc finger zf-C2H2_11 PF16622.5 KFO94848.1 - 0.073 12.8 0.4 0.073 12.8 0.4 2.3 3 0 0 3 3 3 0 zinc-finger C2H2-type HypA PF01155.19 KFO94848.1 - 0.11 12.5 1.3 0.23 11.5 0.3 1.8 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-CCHC_5 PF14787.6 KFO94848.1 - 0.16 11.7 5.8 1.7 8.4 0.6 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-AN1 PF01428.16 KFO94848.1 - 0.19 11.9 0.3 0.19 11.9 0.3 2.4 3 0 0 3 3 2 0 AN1-like Zinc finger XPA_N PF01286.18 KFO94848.1 - 0.19 11.8 4.6 0.92 9.6 1.1 2.3 2 0 0 2 2 2 0 XPA protein N-terminal TFIIS_C PF01096.18 KFO94848.1 - 0.23 11.4 5.2 4.4 7.3 5.2 2.5 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) zf-ribbon_3 PF13248.6 KFO94848.1 - 0.31 10.5 6.4 2.8 7.5 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-LYAR PF08790.11 KFO94848.1 - 0.33 10.9 4.9 6 6.9 0.1 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zinc_ribbon_2 PF13240.6 KFO94848.1 - 0.4 10.5 9.7 0.53 10.1 1.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-H2C2_5 PF13909.6 KFO94848.1 - 0.63 9.9 6.5 4.6 7.1 0.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain RNA_POL_M_15KD PF02150.16 KFO94848.1 - 0.63 10.0 5.1 0.83 9.6 0.1 2.2 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zinc_ribbon_9 PF14369.6 KFO94848.1 - 1.6 9.0 7.0 10 6.5 2.5 2.3 2 0 0 2 2 2 0 zinc-ribbon zf-H2C2_2 PF13465.6 KFO94849.1 - 3.1e-08 33.7 10.3 1.3e-05 25.4 2.6 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFO94849.1 - 4.1e-07 30.1 0.1 4.1e-07 30.1 0.1 1.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO94849.1 - 8.2e-05 23.1 0.2 8.2e-05 23.1 0.2 1.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFO94849.1 - 0.0026 17.5 0.0 0.0038 17.0 0.0 1.3 1 0 0 1 1 1 1 zinc-finger C2H2-type zinc_ribbon_9 PF14369.6 KFO94849.1 - 0.0029 17.8 0.1 0.0046 17.2 0.1 1.4 1 0 0 1 1 1 1 zinc-ribbon zf-Di19 PF05605.12 KFO94849.1 - 0.0068 16.7 0.3 0.0087 16.3 0.3 1.2 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KFO94849.1 - 0.012 15.6 0.3 0.029 14.4 0.3 1.7 1 1 0 1 1 1 0 C2H2-type zinc finger zf_UBZ PF18439.1 KFO94849.1 - 0.042 13.4 0.1 0.073 12.7 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-Binding Zinc Finger zf-C2H2 PF00096.26 KFO94850.1 - 1e-11 44.6 6.9 1.3e-05 25.4 0.9 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO94850.1 - 4.9e-10 39.4 0.8 4.9e-10 39.4 0.8 2.4 3 0 0 3 3 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFO94850.1 - 4.2e-08 33.4 5.9 0.00058 20.5 0.9 2.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-trcl PF13451.6 KFO94850.1 - 0.00034 20.5 2.3 0.057 13.3 0.7 2.2 1 1 1 2 2 2 2 Probable zinc-ribbon domain zf-C2H2_jaz PF12171.8 KFO94850.1 - 0.00056 20.1 1.3 0.028 14.7 0.1 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KFO94850.1 - 0.00063 19.8 2.7 0.095 12.8 0.7 2.2 1 1 1 2 2 2 2 Zinc ribbon domain XPA_N PF01286.18 KFO94850.1 - 0.00072 19.5 4.6 0.016 15.2 0.4 2.2 2 0 0 2 2 2 1 XPA protein N-terminal zf-C2H2_11 PF16622.5 KFO94850.1 - 0.00075 19.2 3.4 0.0053 16.5 0.3 2.3 2 1 0 2 2 2 1 zinc-finger C2H2-type zf_UBZ PF18439.1 KFO94850.1 - 0.00079 19.0 2.3 0.04 13.5 0.3 2.2 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 KFO94850.1 - 0.0017 18.6 4.3 0.035 14.5 0.7 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type LIM PF00412.22 KFO94850.1 - 0.0027 17.9 0.8 0.0074 16.5 0.8 1.6 1 1 0 1 1 1 1 LIM domain zf-LYAR PF08790.11 KFO94850.1 - 0.0034 17.2 6.5 0.47 10.4 0.6 2.2 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 KFO94850.1 - 0.012 15.6 5.6 0.057 13.4 1.7 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Zn_ribbon_recom PF13408.6 KFO94850.1 - 0.021 15.3 0.6 4.2 8.0 0.1 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain zf-ribbon_3 PF13248.6 KFO94850.1 - 0.03 13.7 0.9 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain ADK_lid PF05191.14 KFO94850.1 - 0.035 14.1 0.1 0.056 13.4 0.1 1.4 1 1 0 1 1 1 0 Adenylate kinase, active site lid YhfH PF14149.6 KFO94850.1 - 0.045 13.7 5.0 0.37 10.8 1.2 2.4 1 1 1 2 2 2 0 YhfH-like protein C1_1 PF00130.22 KFO94850.1 - 0.05 13.5 1.6 0.66 9.9 0.6 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_5 PF13909.6 KFO94850.1 - 0.061 13.1 6.3 12 5.8 0.0 3.1 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Zn_Tnp_IS1595 PF12760.7 KFO94850.1 - 0.068 13.2 1.4 0.12 12.4 1.4 1.5 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-C2HE PF16278.5 KFO94850.1 - 0.1 13.0 2.6 0.26 11.8 1.2 1.9 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-AN1 PF01428.16 KFO94850.1 - 0.15 12.2 4.4 0.17 12.0 0.1 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger zf-dskA_traR PF01258.17 KFO94850.1 - 0.16 12.0 3.2 5.2 7.1 0.4 2.2 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Rubredoxin_2 PF18073.1 KFO94850.1 - 0.16 11.7 3.5 1.1 9.0 0.5 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zinc_ribbon_9 PF14369.6 KFO94850.1 - 0.23 11.7 2.4 5 7.5 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon zinc_ribbon_2 PF13240.6 KFO94850.1 - 3 7.7 8.5 1.5 8.6 0.9 2.2 2 0 0 2 2 2 0 zinc-ribbon domain 7tm_4 PF13853.6 KFO94851.1 - 2e-08 34.4 1.3 2.3e-08 34.1 1.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO94851.1 - 0.00024 20.5 0.1 0.00032 20.1 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RVT_1 PF00078.27 KFO94852.1 - 9.5e-07 28.5 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 7tm_4 PF13853.6 KFO94854.1 - 5.6e-08 32.8 0.4 5.7e-08 32.8 0.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO94854.1 - 0.019 14.3 0.6 0.024 14.0 0.6 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF4519 PF15012.6 KFO94854.1 - 0.056 13.6 0.7 0.096 12.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) adh_short_C2 PF13561.6 KFO94855.1 - 8.2e-14 51.7 0.0 9.3e-14 51.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFO94855.1 - 2.6e-10 40.1 0.0 3.3e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase zf-H2C2_2 PF13465.6 KFO94856.1 - 3.9e-29 99.7 53.6 3.4e-09 36.7 0.9 6.6 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFO94856.1 - 5.3e-24 83.3 47.3 7e-06 26.2 2.2 6.2 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO94856.1 - 1.3e-15 56.7 43.1 0.00065 20.3 0.3 6.2 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFO94856.1 - 1.2e-14 53.8 30.8 1.2e-05 25.0 6.9 5.9 6 0 0 6 6 6 4 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KFO94856.1 - 1.1e-07 31.8 22.6 0.00034 20.7 2.0 4.9 2 1 2 4 4 4 3 Zinc ribbon domain XPA_N PF01286.18 KFO94856.1 - 1.1e-06 28.6 24.5 0.86 9.7 0.2 6.2 6 0 0 6 6 6 3 XPA protein N-terminal zf_UBZ PF18439.1 KFO94856.1 - 2.4e-06 27.0 19.6 0.19 11.3 0.0 5.6 6 0 0 6 6 6 3 Ubiquitin-Binding Zinc Finger zf-LYAR PF08790.11 KFO94856.1 - 0.00023 21.0 25.1 1.9 8.5 0.1 6.1 6 0 0 6 6 6 3 LYAR-type C2HC zinc finger zf-C2H2_jaz PF12171.8 KFO94856.1 - 0.00025 21.3 33.7 0.0059 16.9 2.0 5.9 7 0 0 7 7 5 3 Zinc-finger double-stranded RNA-binding zf-trcl PF13451.6 KFO94856.1 - 0.00047 20.0 18.1 0.4 10.6 1.9 5.4 5 1 0 5 5 5 2 Probable zinc-ribbon domain zf-C2HC_2 PF13913.6 KFO94856.1 - 0.0005 19.9 0.6 0.068 13.1 0.0 5.4 5 1 1 6 6 5 2 zinc-finger of a C2HC-type GAGA PF09237.11 KFO94856.1 - 0.0018 18.0 4.8 1.1 9.2 0.0 3.5 3 1 1 4 4 4 2 GAGA factor DUF2256 PF10013.9 KFO94856.1 - 0.0061 16.6 16.0 11 6.3 0.1 5.5 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) FYDLN_acid PF09538.10 KFO94856.1 - 0.01 16.5 13.7 4.7 7.9 0.2 5.1 1 1 3 5 5 5 0 Protein of unknown function (FYDLN_acid) DZR PF12773.7 KFO94856.1 - 0.017 15.1 22.4 1.4e+03 -0.6 22.4 3.8 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 KFO94856.1 - 0.047 13.7 19.8 1.2e+02 2.8 0.8 4.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_6 PF13912.6 KFO94856.1 - 0.047 13.7 46.8 0.083 12.9 0.7 7.1 7 1 0 7 7 7 0 C2H2-type zinc finger zinc_ribbon_9 PF14369.6 KFO94856.1 - 0.058 13.7 19.3 1.1 9.6 0.1 5.3 6 0 0 6 6 5 0 zinc-ribbon CpXC PF14353.6 KFO94856.1 - 0.086 12.9 17.6 0.31 11.1 1.3 4.6 2 1 3 5 5 5 0 CpXC protein YhfH PF14149.6 KFO94856.1 - 0.092 12.7 23.1 2.3 8.2 0.1 5.7 6 1 0 6 6 6 0 YhfH-like protein TerY_C PF15616.6 KFO94856.1 - 0.093 12.8 0.5 0.093 12.8 0.5 2.9 1 1 2 3 3 3 0 TerY-C metal binding domain TRAF6_Z2 PF18048.1 KFO94856.1 - 0.096 12.8 6.7 2.9 8.1 0.4 3.4 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 BolA PF01722.18 KFO94856.1 - 0.11 12.8 2.1 1.7 9.0 0.1 2.8 1 1 2 3 3 3 0 BolA-like protein zinc_ribbon_15 PF17032.5 KFO94856.1 - 0.13 13.0 19.5 0.14 12.9 2.0 3.6 1 1 3 4 4 4 0 zinc-ribbon family zf-ribbon_3 PF13248.6 KFO94856.1 - 0.16 11.4 21.0 0.53 9.8 0.2 5.0 5 0 0 5 5 5 0 zinc-ribbon domain TFIIS_C PF01096.18 KFO94856.1 - 0.53 10.2 26.4 3.4 7.6 0.1 5.7 6 0 0 6 6 6 0 Transcription factor S-II (TFIIS) DUF3268 PF11672.8 KFO94856.1 - 1.4 9.3 13.0 1.2 9.5 0.6 3.2 2 1 2 4 4 4 0 zinc-finger-containing domain Zn_ribbon_SprT PF17283.2 KFO94856.1 - 1.7 8.6 28.0 1.1 9.2 5.1 4.7 4 2 0 4 4 3 0 SprT-like zinc ribbon domain zf-met PF12874.7 KFO94856.1 - 5.4 7.5 33.2 1.4 9.4 1.9 5.9 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zinc_ribbon_5 PF13719.6 KFO94856.1 - 7 6.5 22.0 3.7 7.4 0.1 5.0 5 0 0 5 5 5 0 zinc-ribbon domain YacG PF03884.14 KFO94856.1 - 7.2 6.4 16.6 5.7 6.8 0.1 4.6 5 0 0 5 5 5 0 DNA gyrase inhibitor YacG DNA_RNApol_7kD PF03604.13 KFO94856.1 - 7.3 6.4 19.6 9.4 6.0 0.1 5.4 6 0 0 6 6 6 0 DNA directed RNA polymerase, 7 kDa subunit zf-AN1 PF01428.16 KFO94856.1 - 8.9 6.6 37.2 2.7 8.2 0.1 5.8 4 2 1 5 5 4 0 AN1-like Zinc finger LSM PF01423.22 KFO94857.1 - 3.4e-09 36.3 0.0 4.1e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF2986 PF11661.8 KFO94857.1 - 0.11 13.0 2.9 0.15 12.6 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2986) 7tm_4 PF13853.6 KFO94858.1 - 8.5e-05 22.4 1.6 8.9e-05 22.4 1.6 1.1 1 0 0 1 1 1 1 Olfactory receptor Pkinase PF00069.25 KFO94859.1 - 1.2e-28 100.3 0.6 1.2e-28 100.2 0.6 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO94859.1 - 1.2e-15 57.5 0.1 1.3e-15 57.4 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFO94859.1 - 0.00092 18.6 0.0 0.001 18.5 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFO94859.1 - 0.049 13.5 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-C2H2 PF00096.26 KFO94860.1 - 8.3e-14 51.2 10.8 4.2e-07 30.1 1.6 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO94860.1 - 4.6e-10 39.5 10.1 0.00013 22.5 1.7 2.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFO94860.1 - 9.3e-10 38.5 15.5 1.5e-07 31.5 1.8 3.0 3 0 0 3 3 3 2 Zinc-finger double domain XPA_N PF01286.18 KFO94860.1 - 1.3e-06 28.4 4.6 0.012 15.6 0.3 2.1 2 0 0 2 2 2 2 XPA protein N-terminal zf-C2H2_11 PF16622.5 KFO94860.1 - 2.6e-05 23.9 10.0 0.0043 16.8 2.0 2.1 2 0 0 2 2 2 2 zinc-finger C2H2-type zf_UBZ PF18439.1 KFO94860.1 - 7.5e-05 22.2 2.6 0.11 12.1 0.2 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 KFO94860.1 - 0.00016 21.9 5.9 0.13 12.6 0.3 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KFO94860.1 - 0.00038 20.5 1.8 0.045 13.9 0.1 2.1 2 0 0 2 2 2 1 Zinc ribbon domain zf-LYAR PF08790.11 KFO94860.1 - 0.0031 17.4 2.0 0.15 12.0 0.1 2.4 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 KFO94860.1 - 0.0058 16.6 13.7 0.036 14.1 2.6 2.7 2 1 0 2 2 2 2 C2H2-type zinc finger TFIIS_C PF01096.18 KFO94860.1 - 0.0088 15.9 2.8 0.12 12.2 0.1 2.1 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) YhfH PF14149.6 KFO94860.1 - 0.0095 15.9 2.8 1.2 9.2 0.2 2.2 2 0 0 2 2 2 2 YhfH-like protein zf-UBP PF02148.19 KFO94860.1 - 0.014 15.7 3.9 0.023 15.0 3.9 1.3 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-Di19 PF05605.12 KFO94860.1 - 0.025 14.9 1.9 0.042 14.2 1.9 1.4 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 KFO94860.1 - 0.026 14.5 6.8 1.1 9.4 4.2 2.1 1 1 1 2 2 2 0 BED zinc finger HNH PF01844.23 KFO94860.1 - 0.034 14.3 2.7 1.1 9.5 0.2 2.1 2 0 0 2 2 2 0 HNH endonuclease zf_C2H2_ZHX PF18387.1 KFO94860.1 - 0.035 13.7 6.5 0.4 10.4 0.7 2.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zinc_ribbon_15 PF17032.5 KFO94860.1 - 0.036 14.8 1.3 0.042 14.6 1.3 1.1 1 0 0 1 1 1 0 zinc-ribbon family zf-ribbon_3 PF13248.6 KFO94860.1 - 0.041 13.3 1.2 0.88 9.1 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_3rep PF18868.1 KFO94860.1 - 0.042 14.5 2.1 0.37 11.5 1.0 1.9 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_8 PF15909.5 KFO94860.1 - 0.044 14.1 1.4 0.045 14.0 1.4 1.0 1 0 0 1 1 1 0 C2H2-type zinc ribbon DNA_RNApol_7kD PF03604.13 KFO94860.1 - 0.066 12.9 2.4 1.8 8.3 0.1 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit LIM PF00412.22 KFO94860.1 - 0.073 13.3 2.2 0.3 11.4 2.2 1.8 1 1 0 1 1 1 0 LIM domain zf-H2C2_5 PF13909.6 KFO94860.1 - 0.098 12.4 17.5 0.26 11.1 0.2 3.9 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-met PF12874.7 KFO94860.1 - 0.1 13.0 8.6 0.24 11.9 1.0 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zinc_ribbon_9 PF14369.6 KFO94860.1 - 0.12 12.7 1.3 8.6 6.7 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon zf-C2H2_2 PF12756.7 KFO94860.1 - 0.13 12.6 3.9 0.57 10.5 0.6 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) CxC7 PF18866.1 KFO94860.1 - 0.26 11.4 1.8 3.4 7.9 0.2 2.0 1 1 1 2 2 2 0 CxC7 like cysteine cluster associated with KDZ transposases zf-trcl PF13451.6 KFO94860.1 - 0.31 11.0 3.0 2 8.4 0.1 2.1 2 0 0 2 2 2 0 Probable zinc-ribbon domain Rubredoxin_2 PF18073.1 KFO94860.1 - 0.7 9.7 4.2 9.7 6.0 0.3 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain DUF629 PF04780.12 KFO94860.1 - 0.73 8.3 3.7 1.3 7.4 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zinc_ribbon_2 PF13240.6 KFO94860.1 - 0.85 9.4 5.7 4.5 7.1 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 KFO94860.1 - 0.87 9.6 6.1 2.8 8.0 6.1 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain DUF1390 PF07150.11 KFO94860.1 - 2.4 7.8 4.4 5 6.8 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1390) Zn_ribbon_SprT PF17283.2 KFO94860.1 - 3.1 7.8 8.0 4.8 7.2 3.4 2.8 2 1 0 2 2 2 0 SprT-like zinc ribbon domain Gag_p30 PF02093.16 KFO94861.1 - 4.4e-21 75.4 0.0 5.4e-21 75.1 0.0 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein zf-C2H2 PF00096.26 KFO94862.1 - 1.1e-13 50.8 11.6 3.1e-07 30.5 1.0 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO94862.1 - 1.5e-09 37.8 15.2 5.5e-09 36.0 2.0 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFO94862.1 - 1.6e-08 34.7 10.6 0.00056 20.5 0.8 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFO94862.1 - 2.8e-06 27.1 6.5 3.6e-05 23.6 0.1 2.4 3 0 0 3 3 2 1 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KFO94862.1 - 1.6e-05 24.4 2.1 0.046 13.3 0.5 2.1 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 KFO94862.1 - 5.9e-05 22.7 6.6 0.00051 19.7 0.8 2.1 2 0 0 2 2 2 1 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KFO94862.1 - 6.6e-05 22.9 2.3 0.019 15.0 0.5 2.1 2 0 0 2 2 2 2 Zinc ribbon domain XPA_N PF01286.18 KFO94862.1 - 0.00012 22.0 2.0 0.0083 16.1 0.2 2.1 2 0 0 2 2 2 1 XPA protein N-terminal zf-C2H2_6 PF13912.6 KFO94862.1 - 0.00029 20.8 13.5 0.0018 18.2 0.6 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger CpXC PF14353.6 KFO94862.1 - 0.00038 20.5 0.6 0.064 13.3 0.6 2.0 1 1 0 1 1 1 1 CpXC protein ADK_lid PF05191.14 KFO94862.1 - 0.00043 20.2 4.2 0.11 12.5 0.9 2.2 2 0 0 2 2 2 2 Adenylate kinase, active site lid Zn_ribbon_SprT PF17283.2 KFO94862.1 - 0.00065 19.6 5.1 0.055 13.4 0.7 2.6 1 1 1 2 2 2 1 SprT-like zinc ribbon domain DZR PF12773.7 KFO94862.1 - 0.00077 19.4 0.4 0.00095 19.2 0.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-Di19 PF05605.12 KFO94862.1 - 0.00092 19.5 2.5 0.0077 16.5 2.5 1.9 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding YhfH PF14149.6 KFO94862.1 - 0.0017 18.3 0.4 0.36 10.9 0.0 2.2 2 0 0 2 2 2 1 YhfH-like protein TF_Zn_Ribbon PF08271.12 KFO94862.1 - 0.0021 17.5 0.7 0.39 10.3 0.1 2.1 2 0 0 2 2 2 1 TFIIB zinc-binding zinc_ribbon_9 PF14369.6 KFO94862.1 - 0.0026 18.0 0.9 0.38 11.1 0.0 2.1 2 0 0 2 2 2 1 zinc-ribbon Ogr_Delta PF04606.12 KFO94862.1 - 0.0037 17.2 1.7 0.035 14.1 1.7 1.9 1 1 0 1 1 1 1 Ogr/Delta-like zinc finger zf-ribbon_3 PF13248.6 KFO94862.1 - 0.004 16.5 3.9 0.49 9.9 0.2 2.2 2 0 0 2 2 2 2 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 KFO94862.1 - 0.0042 17.0 2.3 0.065 13.2 2.3 2.0 1 1 1 2 2 2 1 Transposase zinc-ribbon domain zf-TFIIB PF13453.6 KFO94862.1 - 0.0045 16.3 0.6 1.6 8.2 0.0 2.2 2 1 0 2 2 2 1 Transcription factor zinc-finger zf-LYAR PF08790.11 KFO94862.1 - 0.0054 16.6 5.1 0.11 12.4 1.8 2.2 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-Mss51 PF13824.6 KFO94862.1 - 0.0061 16.6 3.8 0.033 14.3 3.8 1.9 1 1 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 YacG PF03884.14 KFO94862.1 - 0.007 16.1 1.2 1.9 8.3 0.1 2.1 2 0 0 2 2 2 1 DNA gyrase inhibitor YacG FYDLN_acid PF09538.10 KFO94862.1 - 0.0071 17.0 0.3 2.5 8.8 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (FYDLN_acid) Zn-C2H2_12 PF18112.1 KFO94862.1 - 0.0077 16.7 1.0 4 8.0 0.0 2.3 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C4_Topoisom PF01396.19 KFO94862.1 - 0.012 15.4 1.3 2.6 7.9 0.1 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-C2H2_9 PF16293.5 KFO94862.1 - 0.012 15.5 0.8 0.35 10.7 0.0 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_5 PF13719.6 KFO94862.1 - 0.013 15.3 1.9 2 8.2 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_recom PF13408.6 KFO94862.1 - 0.015 15.8 0.9 1.8 9.1 0.3 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Rad50_zn_hook PF04423.14 KFO94862.1 - 0.015 15.1 0.6 1.9 8.4 0.0 2.2 2 1 0 2 2 2 0 Rad50 zinc hook motif zinc_ribbon_4 PF13717.6 KFO94862.1 - 0.016 15.1 3.1 1.6 8.7 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.19 KFO94862.1 - 0.02 14.9 0.1 0.037 14.0 0.1 1.5 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.5 KFO94862.1 - 0.027 15.2 0.4 0.035 14.8 0.4 1.2 1 0 0 1 1 1 0 zinc-ribbon family Prok-RING_1 PF14446.6 KFO94862.1 - 0.028 14.4 3.7 0.37 10.7 0.6 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF4379 PF14311.6 KFO94862.1 - 0.032 14.6 0.3 0.5 10.8 0.3 2.0 1 1 1 2 2 2 0 Probable Zinc-ribbon domain DUF2256 PF10013.9 KFO94862.1 - 0.04 14.0 0.8 6.7 6.9 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) TFIIS_C PF01096.18 KFO94862.1 - 0.041 13.7 2.4 2.5 8.0 0.2 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Cys_rich_CPXG PF14255.6 KFO94862.1 - 0.05 13.5 0.6 4.4 7.3 0.1 2.2 2 0 0 2 2 2 0 Cysteine-rich CPXCG TerY_C PF15616.6 KFO94862.1 - 0.058 13.5 0.2 0.063 13.4 0.2 1.1 1 0 0 1 1 1 0 TerY-C metal binding domain zf-trcl PF13451.6 KFO94862.1 - 0.059 13.3 1.1 2.2 8.2 0.1 2.1 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-C2H2_jaz PF12171.8 KFO94862.1 - 0.081 13.2 3.7 1 9.8 1.6 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_2 PF13240.6 KFO94862.1 - 0.086 12.6 8.1 1.5 8.7 1.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-ACC PF17848.1 KFO94862.1 - 0.087 12.9 3.2 2.8 8.1 0.3 2.4 2 1 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain DUF35_N PF12172.8 KFO94862.1 - 0.098 12.6 4.4 1 9.3 0.3 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) A2L_zn_ribbon PF08792.10 KFO94862.1 - 0.11 12.3 2.5 5.7 6.8 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain TRAF6_Z2 PF18048.1 KFO94862.1 - 0.12 12.5 4.2 3.1 8.0 2.7 2.3 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 DUF2225 PF09986.9 KFO94862.1 - 0.12 12.1 0.7 1.6 8.4 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-AN1 PF01428.16 KFO94862.1 - 0.12 12.6 5.4 1.6 8.9 2.7 2.3 1 1 1 2 2 2 0 AN1-like Zinc finger zf-BED PF02892.15 KFO94862.1 - 0.12 12.4 3.0 0.27 11.3 1.1 2.1 1 1 1 2 2 2 0 BED zinc finger T4_baseplate PF12322.8 KFO94862.1 - 0.14 11.6 0.2 0.91 9.0 0.1 1.9 1 1 1 2 2 2 0 T4 bacteriophage base plate protein zf-C2HE PF16278.5 KFO94862.1 - 0.15 12.5 6.5 2.4 8.7 2.1 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-HIT PF04438.16 KFO94862.1 - 0.16 11.9 5.6 0.39 10.6 0.7 2.1 2 0 0 2 2 2 0 HIT zinc finger zf-CCHC_5 PF14787.6 KFO94862.1 - 0.16 11.7 5.4 3 7.6 0.2 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger HNH PF01844.23 KFO94862.1 - 0.16 12.2 3.5 6.8 7.0 0.9 2.1 2 0 0 2 2 2 0 HNH endonuclease zf-ISL3 PF14690.6 KFO94862.1 - 0.17 12.6 2.6 12 6.6 0.1 2.2 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-H2C2_5 PF13909.6 KFO94862.1 - 0.18 11.6 0.1 0.18 11.6 0.1 2.8 3 0 0 3 3 2 0 C2H2-type zinc-finger domain zf-IS66 PF13005.7 KFO94862.1 - 0.31 11.5 3.1 9.8 6.7 0.8 2.2 1 1 0 2 2 2 0 zinc-finger binding domain of transposase IS66 DUF1610 PF07754.11 KFO94862.1 - 0.4 10.7 9.6 1.5 8.9 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) DNA_ligase_ZBD PF03119.16 KFO94862.1 - 0.43 10.7 3.6 6.9 6.8 0.3 2.1 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Rubredoxin_2 PF18073.1 KFO94862.1 - 0.82 9.4 4.8 2.3 8.0 0.6 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain UPF0547 PF10571.9 KFO94862.1 - 1.1 9.4 5.4 5.8 7.1 0.7 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf_C2H2_13 PF18508.1 KFO94862.1 - 1.2 8.8 4.8 2 8.1 0.1 2.5 2 1 0 2 2 2 0 Zinc finger domain zf-tcix PF14952.6 KFO94862.1 - 5.5 6.7 7.7 12 5.6 1.1 2.2 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding 7tm_4 PF13853.6 KFO94863.1 - 3.9e-23 82.6 7.5 4.4e-23 82.4 7.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO94863.1 - 2.1e-06 27.2 7.5 6.6e-06 25.6 7.5 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-H2C2_2 PF13465.6 KFO94865.1 - 5.6e-11 42.3 15.6 1.2e-07 31.9 2.0 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_11 PF16622.5 KFO94865.1 - 1.9e-06 27.5 0.8 1.9e-06 27.5 0.8 3.1 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-C2H2 PF00096.26 KFO94865.1 - 2e-06 27.9 3.3 2e-06 27.9 3.3 3.1 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO94865.1 - 0.00043 20.9 2.4 0.00043 20.9 2.4 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFO94865.1 - 0.003 17.6 3.6 0.0055 16.8 3.6 1.5 1 1 0 1 1 1 1 Zinc ribbon domain zf-LYAR PF08790.11 KFO94865.1 - 0.039 13.8 0.4 0.039 13.8 0.4 2.1 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_jaz PF12171.8 KFO94865.1 - 0.12 12.7 0.1 0.12 12.7 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFO94865.1 - 0.22 11.8 2.3 0.27 11.6 2.3 1.1 1 0 0 1 1 1 0 BolA-like protein zf_C2H2_ZHX PF18387.1 KFO94865.1 - 4.7 6.9 9.4 0.1 12.3 1.3 2.2 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain RVT_1 PF00078.27 KFO94866.1 - 1.3e-07 31.4 0.0 2.1e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ILEI PF15711.5 KFO94867.1 - 1.8e-21 76.4 0.0 2e-21 76.3 0.0 1.0 1 0 0 1 1 1 1 Interleukin-like EMT inducer zf-C2H2 PF00096.26 KFO94868.1 - 7.6e-14 51.3 6.2 4.2e-08 33.2 2.9 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO94868.1 - 2e-08 34.4 5.7 0.00029 21.4 2.2 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFO94868.1 - 6.8e-06 26.3 0.5 6.8e-06 26.3 0.5 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFO94868.1 - 0.00016 21.8 0.3 0.06 13.6 0.3 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFO94868.1 - 0.00029 20.5 8.9 0.0018 18.0 0.5 2.1 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-LYAR PF08790.11 KFO94868.1 - 0.00059 19.7 1.4 0.51 10.3 0.3 2.2 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger Zn-ribbon_8 PF09723.10 KFO94868.1 - 0.00088 19.3 1.5 0.018 15.2 1.5 2.1 1 1 1 2 2 2 2 Zinc ribbon domain zf_UBZ PF18439.1 KFO94868.1 - 0.0018 17.8 0.7 0.17 11.5 0.3 2.2 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger XPA_N PF01286.18 KFO94868.1 - 0.0023 18.0 1.5 1.4 9.1 0.1 2.2 2 0 0 2 2 2 2 XPA protein N-terminal zf-C2HC_2 PF13913.6 KFO94868.1 - 0.0042 17.0 8.7 0.078 12.9 4.3 2.8 2 1 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 KFO94868.1 - 0.013 15.8 0.6 3.2 8.2 0.5 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DZR PF12773.7 KFO94868.1 - 0.016 15.2 1.8 0.022 14.8 1.8 1.3 1 0 0 1 1 1 0 Double zinc ribbon GAGA PF09237.11 KFO94868.1 - 0.021 14.6 0.3 0.023 14.5 0.3 1.3 1 1 0 1 1 1 0 GAGA factor zf-Paramyx-P PF13008.7 KFO94868.1 - 0.033 13.7 0.7 0.033 13.7 0.7 1.5 2 0 0 2 2 2 0 Zinc-binding domain of Paramyxoviridae V protein zinc_ribbon_5 PF13719.6 KFO94868.1 - 0.044 13.6 3.2 0.074 12.8 0.3 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-BED PF02892.15 KFO94868.1 - 0.049 13.7 3.5 0.94 9.6 0.1 2.2 1 1 1 2 2 2 0 BED zinc finger zinc_ribbon_9 PF14369.6 KFO94868.1 - 0.056 13.7 3.3 1.8 8.9 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon Sgf11 PF08209.11 KFO94868.1 - 0.11 12.1 3.7 1.1 8.9 1.6 2.7 2 2 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf_C2H2_ZHX PF18387.1 KFO94868.1 - 0.12 12.1 1.2 6.4 6.5 0.5 2.0 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-Di19 PF05605.12 KFO94868.1 - 0.13 12.6 2.8 1.3 9.4 1.3 2.3 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 KFO94868.1 - 0.15 12.5 5.2 2.5 8.6 2.8 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_4 PF13717.6 KFO94868.1 - 0.25 11.3 3.1 0.59 10.1 0.6 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 KFO94868.1 - 0.27 11.3 0.6 0.27 11.3 0.6 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger TFIIS_C PF01096.18 KFO94868.1 - 0.67 9.9 5.5 0.96 9.4 1.0 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-ribbon_3 PF13248.6 KFO94868.1 - 3 7.4 10.4 0.43 10.1 2.7 2.5 2 1 0 2 2 2 0 zinc-ribbon domain TRAF6_Z2 PF18048.1 KFO94868.1 - 3.3 7.9 8.9 0.66 10.1 1.6 2.6 2 1 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 7tm_4 PF13853.6 KFO94869.1 - 7.9e-16 58.6 2.0 8.7e-16 58.5 2.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO94869.1 - 0.003 16.9 4.9 0.0056 16.0 4.9 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-H2C2_2 PF13465.6 KFO94870.1 - 3.3e-07 30.4 18.7 0.00016 21.9 1.5 2.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFO94870.1 - 0.0001 22.5 4.6 0.0001 22.5 4.6 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KFO94870.1 - 0.00045 19.9 10.8 0.0017 18.0 0.3 2.6 3 0 0 3 3 3 2 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KFO94870.1 - 0.015 15.4 7.3 0.015 15.4 7.3 2.7 2 1 0 2 2 2 0 Zinc ribbon domain zf-C2H2_4 PF13894.6 KFO94870.1 - 0.016 16.0 3.7 0.016 16.0 3.7 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger TFIIS_C PF01096.18 KFO94870.1 - 0.069 13.0 6.0 0.54 10.2 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf_UBZ PF18439.1 KFO94870.1 - 0.072 12.7 0.2 0.072 12.7 0.2 2.8 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-trcl PF13451.6 KFO94870.1 - 0.08 12.8 5.2 2.6 8.0 2.0 2.4 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-UBP PF02148.19 KFO94870.1 - 0.19 12.1 8.2 0.063 13.6 5.2 1.9 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein HypA PF01155.19 KFO94870.1 - 0.3 11.1 5.5 0.43 10.6 5.5 1.3 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA XPA_N PF01286.18 KFO94870.1 - 0.48 10.5 0.1 0.48 10.5 0.1 2.7 3 0 0 3 3 3 0 XPA protein N-terminal YhfH PF14149.6 KFO94870.1 - 0.93 9.5 10.0 4 7.5 0.1 3.0 3 1 0 3 3 3 0 YhfH-like protein zf-C2H2_6 PF13912.6 KFO94870.1 - 0.99 9.5 16.3 0.44 10.6 4.6 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO94870.1 - 1.7 9.0 9.7 0.28 11.5 1.2 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 KFO94870.1 - 2.1 8.3 8.7 0.32 10.9 1.5 2.9 3 1 0 3 3 3 0 LYAR-type C2HC zinc finger zf-AN1 PF01428.16 KFO94870.1 - 3.2 8.0 18.4 2.7 8.2 4.0 3.2 2 1 1 3 3 3 0 AN1-like Zinc finger zf-H2C2_5 PF13909.6 KFO94870.1 - 3.9 7.3 0.0 3.9 7.3 0.0 3.8 4 0 0 4 4 4 0 C2H2-type zinc-finger domain Granulin PF00396.18 KFO94871.1 - 6.1 7.3 35.4 30 5.1 15.7 4.1 2 1 1 3 3 3 0 Granulin zf-H2C2_2 PF13465.6 KFO94872.1 - 2.7e-36 122.4 45.8 1.3e-09 38.0 1.3 6.1 6 0 0 6 6 6 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFO94872.1 - 4.5e-29 99.3 45.5 1.7e-07 31.3 0.4 5.1 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO94872.1 - 2.1e-19 68.6 40.6 0.00031 21.3 0.2 5.1 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFO94872.1 - 1.5e-10 40.6 28.7 0.00033 20.4 1.4 4.6 5 0 0 5 5 5 3 zinc-finger C2H2-type XPA_N PF01286.18 KFO94872.1 - 2.1e-08 34.1 15.4 0.021 14.9 0.3 5.1 5 0 0 5 5 5 2 XPA protein N-terminal Zn-ribbon_8 PF09723.10 KFO94872.1 - 1.6e-07 31.3 22.3 0.0081 16.3 6.1 4.0 1 1 4 5 5 5 4 Zinc ribbon domain zf-C2H2_jaz PF12171.8 KFO94872.1 - 1.8e-07 31.2 19.4 0.0028 17.9 2.1 4.8 5 0 0 5 5 4 3 Zinc-finger double-stranded RNA-binding zinc_ribbon_9 PF14369.6 KFO94872.1 - 3.8e-07 30.2 12.8 0.078 13.3 0.1 5.0 5 0 0 5 5 5 2 zinc-ribbon zf_UBZ PF18439.1 KFO94872.1 - 9.4e-07 28.3 17.0 0.34 10.5 0.0 5.2 5 0 0 5 5 5 2 Ubiquitin-Binding Zinc Finger C1_4 PF07975.12 KFO94872.1 - 4.5e-06 26.8 13.6 0.0062 16.7 1.1 4.0 2 1 2 4 4 4 2 TFIIH C1-like domain GAGA PF09237.11 KFO94872.1 - 2.7e-05 23.9 0.6 0.0058 16.4 0.1 2.5 1 1 1 2 2 2 1 GAGA factor FYDLN_acid PF09538.10 KFO94872.1 - 6e-05 23.7 9.6 0.21 12.3 0.2 4.3 1 1 2 3 3 3 1 Protein of unknown function (FYDLN_acid) zf-C2HC_2 PF13913.6 KFO94872.1 - 0.00013 21.8 23.4 0.069 13.1 1.7 4.9 5 0 0 5 5 5 3 zinc-finger of a C2HC-type DZR PF12773.7 KFO94872.1 - 0.00024 21.0 19.1 47 4.1 19.1 3.2 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 KFO94872.1 - 0.00025 21.1 13.8 93 3.1 13.8 3.1 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Di19 PF05605.12 KFO94872.1 - 0.00045 20.5 15.1 0.0035 17.6 3.3 3.7 1 1 3 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_15 PF17032.5 KFO94872.1 - 0.00066 20.4 15.3 0.038 14.7 0.9 3.1 1 1 3 4 4 4 3 zinc-ribbon family FYVE PF01363.21 KFO94872.1 - 0.00091 19.3 22.7 0.017 15.3 3.1 3.1 1 1 2 3 3 3 2 FYVE zinc finger zf-C2H2_6 PF13912.6 KFO94872.1 - 0.00092 19.1 41.8 0.32 11.0 0.3 6.3 5 2 0 5 5 5 3 C2H2-type zinc finger zf-trcl PF13451.6 KFO94872.1 - 0.001 18.9 15.1 0.83 9.6 0.1 4.9 5 0 0 5 5 5 1 Probable zinc-ribbon domain Zn_ribbon_SprT PF17283.2 KFO94872.1 - 0.0011 18.8 27.3 0.062 13.2 8.1 4.3 3 1 0 3 3 3 2 SprT-like zinc ribbon domain zf-LYAR PF08790.11 KFO94872.1 - 0.0013 18.6 21.0 1.9 8.4 0.3 5.2 5 0 0 5 5 5 2 LYAR-type C2HC zinc finger zf-HIT PF04438.16 KFO94872.1 - 0.0019 18.1 24.6 0.13 12.1 2.4 5.0 5 0 0 5 5 5 2 HIT zinc finger DUF2256 PF10013.9 KFO94872.1 - 0.0023 18.0 14.3 1.6 8.9 0.1 5.1 5 0 0 5 5 5 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-AN1 PF01428.16 KFO94872.1 - 0.0041 17.3 30.8 0.02 15.1 0.8 5.3 3 1 2 5 5 5 1 AN1-like Zinc finger ADK_lid PF05191.14 KFO94872.1 - 0.0041 17.1 13.9 0.033 14.2 0.9 3.9 3 2 0 3 3 3 2 Adenylate kinase, active site lid zf-H2C2_5 PF13909.6 KFO94872.1 - 0.0058 16.4 0.1 0.0058 16.4 0.1 8.2 8 3 0 8 8 6 1 C2H2-type zinc-finger domain zf-met PF12874.7 KFO94872.1 - 0.006 16.9 21.8 0.32 11.4 1.7 4.6 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-BED PF02892.15 KFO94872.1 - 0.0081 16.2 29.9 0.32 11.1 1.1 5.1 1 1 2 3 3 3 1 BED zinc finger DUF3268 PF11672.8 KFO94872.1 - 0.016 15.6 9.5 0.26 11.6 0.8 3.0 2 1 0 3 3 3 0 zinc-finger-containing domain zf-ribbon_3 PF13248.6 KFO94872.1 - 0.018 14.4 18.5 0.46 10.0 0.1 5.0 5 0 0 5 5 5 0 zinc-ribbon domain YhfH PF14149.6 KFO94872.1 - 0.056 13.4 18.5 5.2 7.1 0.2 4.8 5 0 0 5 5 5 0 YhfH-like protein zinc-ribbons_6 PF07191.12 KFO94872.1 - 0.06 13.3 18.4 12 5.9 3.1 4.0 1 1 1 2 2 2 0 zinc-ribbons TFIIS_C PF01096.18 KFO94872.1 - 0.061 13.2 24.0 2.2 8.2 0.5 5.2 5 0 0 5 5 5 0 Transcription factor S-II (TFIIS) zinc_ribbon_4 PF13717.6 KFO94872.1 - 0.065 13.2 21.2 1.8 8.5 5.3 5.0 4 1 0 4 4 4 0 zinc-ribbon domain zf-C2H2_9 PF16293.5 KFO94872.1 - 0.099 12.5 7.6 5.7 6.9 0.0 4.1 2 2 2 4 4 4 0 C2H2 type zinc-finger (1 copy) Zf_RING PF16744.5 KFO94872.1 - 0.16 12.1 14.6 0.41 10.8 0.2 4.0 1 1 2 4 4 4 0 KIAA1045 RING finger IBR PF01485.21 KFO94872.1 - 0.47 10.7 26.2 5.5 7.3 13.7 3.9 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Ribosomal_L37ae PF01780.19 KFO94872.1 - 0.48 10.5 20.0 16 5.7 0.4 4.8 1 1 3 4 4 4 0 Ribosomal L37ae protein family zf-FPG_IleRS PF06827.14 KFO94872.1 - 1.1 9.2 17.7 13 5.8 0.3 5.2 4 1 0 4 4 4 0 Zinc finger found in FPG and IleRS Zn_Tnp_IS1595 PF12760.7 KFO94872.1 - 1.1 9.2 32.3 6.5 6.8 6.2 4.4 3 2 1 4 4 4 0 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.12 KFO94872.1 - 1.2 8.7 19.8 7.1 6.2 2.2 4.6 5 0 0 5 5 5 0 TFIIB zinc-binding CpXC PF14353.6 KFO94872.1 - 1.2 9.1 19.4 2.9 8.0 2.1 4.7 1 1 4 5 5 5 0 CpXC protein zf-C2HE PF16278.5 KFO94872.1 - 1.6 9.2 28.2 0.83 10.1 0.2 5.0 1 1 4 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger LIM PF00412.22 KFO94872.1 - 1.6 9.0 20.0 12 6.2 0.2 4.5 1 1 2 4 4 3 0 LIM domain zf-RING_7 PF02591.15 KFO94872.1 - 1.8 8.8 15.8 1.5 9.1 0.2 4.9 5 0 0 5 5 5 0 C4-type zinc ribbon domain zinc_ribbon_5 PF13719.6 KFO94872.1 - 2.9 7.7 17.5 11 5.9 0.7 4.7 5 0 0 5 5 5 0 zinc-ribbon domain HalOD2 PF18547.1 KFO94872.1 - 3 7.8 17.0 2.9 7.9 1.0 4.4 3 2 0 3 3 3 0 Halobacterial output domain 2 Desulfoferrod_N PF06397.12 KFO94872.1 - 3.7 7.3 16.5 5.4 6.7 0.3 4.7 5 0 0 5 5 5 0 Desulfoferrodoxin, N-terminal domain TerY_C PF15616.6 KFO94872.1 - 5.4 7.1 11.3 1.1 9.4 0.3 2.7 1 1 2 3 3 3 0 TerY-C metal binding domain DNA_RNApol_7kD PF03604.13 KFO94872.1 - 6.8 6.5 18.1 6.8 6.5 0.2 5.0 5 0 0 5 5 5 0 DNA directed RNA polymerase, 7 kDa subunit Albumin_I PF08027.11 KFO94873.1 - 0.00037 20.0 5.1 5.5 6.7 0.1 4.7 3 0 0 3 3 3 3 Albumin I chain b 7tm_4 PF13853.6 KFO94874.1 - 3.5e-09 36.8 0.9 3.9e-09 36.6 0.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO94874.1 - 2.1e-06 27.3 0.1 2.5e-06 27.0 0.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CholecysA-Rec_N PF09193.10 KFO94874.1 - 0.047 13.7 0.2 0.082 12.9 0.1 1.5 1 1 1 2 2 2 0 Cholecystokinin A receptor, N-terminal zf-H2C2_2 PF13465.6 KFO94875.1 - 1.1e-35 120.4 35.7 3.3e-08 33.6 1.3 6.2 6 0 0 6 6 6 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFO94875.1 - 2.2e-26 90.8 40.5 4.5e-08 33.1 0.6 6.1 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO94875.1 - 1.4e-17 62.9 36.6 0.00033 21.3 0.4 6.1 6 0 0 6 6 6 5 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFO94875.1 - 3e-08 33.6 20.7 0.0034 17.5 0.9 4.3 4 0 0 4 4 4 3 Zinc ribbon domain zf-C2H2_11 PF16622.5 KFO94875.1 - 3e-07 30.1 23.5 0.041 13.6 0.1 6.0 6 0 0 6 6 6 3 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFO94875.1 - 8.4e-07 29.1 14.8 0.18 12.1 0.0 5.3 6 0 0 6 6 5 3 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFO94875.1 - 4.7e-06 26.1 25.3 0.025 14.2 0.1 6.1 6 0 0 6 6 6 2 Ubiquitin-Binding Zinc Finger zf-LYAR PF08790.11 KFO94875.1 - 1.5e-05 24.8 26.6 0.017 15.0 0.3 6.2 6 0 0 6 6 6 2 LYAR-type C2HC zinc finger XPA_N PF01286.18 KFO94875.1 - 5.8e-05 23.0 19.5 3.7 7.7 0.7 6.1 6 0 0 6 6 6 1 XPA protein N-terminal zinc_ribbon_15 PF17032.5 KFO94875.1 - 0.0003 21.5 11.7 0.32 11.8 0.1 3.3 2 1 1 3 3 3 1 zinc-ribbon family zf-Di19 PF05605.12 KFO94875.1 - 0.00064 20.0 22.5 0.019 15.3 2.7 4.4 1 1 2 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-trcl PF13451.6 KFO94875.1 - 0.0014 18.5 18.9 4.4 7.3 9.0 5.1 4 1 0 4 4 4 0 Probable zinc-ribbon domain zinc_ribbon_9 PF14369.6 KFO94875.1 - 0.0017 18.5 17.9 0.11 12.8 0.0 5.9 5 1 1 6 6 6 1 zinc-ribbon Evr1_Alr PF04777.13 KFO94875.1 - 0.002 18.6 10.1 0.27 11.7 1.5 3.8 1 1 1 2 2 2 1 Erv1 / Alr family ADK_lid PF05191.14 KFO94875.1 - 0.0059 16.6 21.3 0.28 11.2 0.5 5.3 3 1 2 5 5 5 2 Adenylate kinase, active site lid DUF2256 PF10013.9 KFO94875.1 - 0.0071 16.4 19.2 7 6.9 0.2 5.6 6 0 0 6 6 5 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn_Tnp_IS1595 PF12760.7 KFO94875.1 - 0.013 15.5 2.3 0.013 15.5 2.3 4.2 3 2 0 4 4 4 0 Transposase zinc-ribbon domain zf-met PF12874.7 KFO94875.1 - 0.019 15.4 0.1 0.019 15.4 0.1 4.6 5 0 0 5 5 4 0 Zinc-finger of C2H2 type YhfH PF14149.6 KFO94875.1 - 0.019 14.9 21.9 6.6 6.8 0.1 5.9 6 0 0 6 6 6 0 YhfH-like protein HypA PF01155.19 KFO94875.1 - 0.02 14.9 16.5 2.7 8.1 1.1 3.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KFO94875.1 - 0.025 14.6 22.7 1.4e+03 -0.6 22.7 3.9 1 1 0 1 1 1 0 Double zinc ribbon TerY_C PF15616.6 KFO94875.1 - 0.028 14.5 7.2 0.14 12.3 0.2 2.8 1 1 2 3 3 3 0 TerY-C metal binding domain zf-C2HC_2 PF13913.6 KFO94875.1 - 0.058 13.3 0.2 0.058 13.3 0.2 4.4 5 0 0 5 5 3 0 zinc-finger of a C2HC-type FYDLN_acid PF09538.10 KFO94875.1 - 0.075 13.7 12.9 13 6.5 0.9 5.1 1 1 4 5 5 5 0 Protein of unknown function (FYDLN_acid) CpXC PF14353.6 KFO94875.1 - 0.09 12.8 19.2 0.47 10.5 0.1 5.1 2 1 4 6 6 6 0 CpXC protein DUF3268 PF11672.8 KFO94875.1 - 0.12 12.7 10.5 1.1 9.6 1.3 3.1 2 1 2 4 4 4 0 zinc-finger-containing domain IBR PF01485.21 KFO94875.1 - 0.2 11.9 22.7 2.9 8.2 2.4 3.6 1 1 3 4 4 4 0 IBR domain, a half RING-finger domain LIM PF00412.22 KFO94875.1 - 0.8 10.0 21.3 1.8 8.9 2.1 5.0 3 2 1 4 4 3 0 LIM domain zf-ribbon_3 PF13248.6 KFO94875.1 - 0.99 8.9 21.8 0.92 9.0 0.2 5.5 6 0 0 6 6 6 0 zinc-ribbon domain Zn-C2H2_12 PF18112.1 KFO94875.1 - 1.1 9.8 0.1 1.1 9.8 0.1 3.7 4 0 0 4 4 3 0 Autophagy receptor zinc finger-C2H2 domain zf-BED PF02892.15 KFO94875.1 - 1.6 8.8 23.2 9.8 6.3 1.3 5.2 1 1 4 5 5 5 0 BED zinc finger HalOD2 PF18547.1 KFO94875.1 - 1.8 8.5 19.0 11 6.0 3.2 5.0 3 1 2 5 5 5 0 Halobacterial output domain 2 C1_4 PF07975.12 KFO94875.1 - 2.9 8.2 22.5 1.3 9.3 0.1 4.8 1 1 3 5 5 5 0 TFIIH C1-like domain TFIIS_C PF01096.18 KFO94875.1 - 4 7.4 27.5 3.2 7.7 0.1 5.8 5 1 0 5 5 5 0 Transcription factor S-II (TFIIS) Thioredoxin_4 PF13462.6 KFO94875.1 - 5.6 7.1 7.6 31 4.7 0.3 3.3 2 2 2 4 4 4 0 Thioredoxin DUF1610 PF07754.11 KFO94875.1 - 7.1 6.7 19.0 4.2 7.4 0.1 5.1 5 0 0 5 5 5 0 Domain of unknown function (DUF1610) zinc_ribbon_2 PF13240.6 KFO94875.1 - 7.4 6.4 30.5 5.4 6.9 0.2 6.2 6 0 0 6 6 6 0 zinc-ribbon domain Mut7-C PF01927.16 KFO94875.1 - 7.8 6.6 17.5 1.5 8.9 2.4 4.0 1 1 3 4 4 4 0 Mut7-C RNAse domain zf-AN1 PF01428.16 KFO94875.1 - 7.8 6.8 32.4 4.1 7.6 0.3 6.1 5 1 1 6 6 5 0 AN1-like Zinc finger zf-C2H2_6 PF13912.6 KFO94875.1 - 8.3 6.5 44.0 1.2 9.2 1.4 7.0 8 0 0 8 8 6 0 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 KFO94875.1 - 9.3 6.3 28.4 3.6 7.6 2.5 5.4 2 2 2 4 4 4 0 SprT-like zinc ribbon domain 7tm_4 PF13853.6 KFO94876.1 - 4.4e-14 52.9 0.9 5.1e-14 52.7 0.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO94876.1 - 2.5e-09 36.9 0.3 3.1e-09 36.5 0.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CholecysA-Rec_N PF09193.10 KFO94876.1 - 0.072 13.1 0.1 0.14 12.2 0.1 1.6 1 1 0 1 1 1 0 Cholecystokinin A receptor, N-terminal 7tm_4 PF13853.6 KFO94877.1 - 1.8e-15 57.4 2.2 2.2e-15 57.1 2.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_4 PF13853.6 KFO94878.1 - 4.4e-50 171.0 13.9 5.1e-50 170.8 13.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO94878.1 - 2.5e-31 109.0 15.5 3.4e-31 108.5 15.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFO94878.1 - 0.00033 20.1 14.5 0.00053 19.4 14.5 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2189 PF09955.9 KFO94878.1 - 0.58 10.4 8.1 7.2 6.9 0.1 3.2 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2189) F_actin_bund_C PF18060.1 KFO94879.1 - 0.066 13.4 0.0 0.068 13.3 0.0 1.0 1 0 0 1 1 1 0 F actin bundling C terminal Ribosomal_S30 PF04758.14 KFO94880.1 - 6.6e-17 61.4 9.0 7.1e-17 61.4 9.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Flavodoxin_NdrI PF07972.11 KFO94880.1 - 0.071 13.3 0.0 0.073 13.2 0.0 1.0 1 0 0 1 1 1 0 NrdI Flavodoxin like Oxidored_q3 PF00499.20 KFO94882.1 - 3.6e-15 55.9 8.2 3.6e-15 55.9 8.2 1.4 2 0 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DIM PF08194.12 KFO94882.1 - 1 9.6 0.1 1 9.6 0.1 2.7 2 1 0 2 2 2 0 DIM protein Histone PF00125.24 KFO94884.1 - 2.2e-29 102.5 1.1 2.4e-29 102.3 1.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 KFO94884.1 - 5.4e-05 23.8 2.1 6.3e-05 23.6 2.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain HRG PF16954.5 KFO94885.1 - 5.2e-07 30.0 8.5 1.7e-06 28.3 1.1 2.0 2 0 0 2 2 2 2 Haem-transporter, endosomal/lysosomal, haem-responsive gene Col_cuticle_N PF01484.17 KFO94885.1 - 0.039 14.0 0.2 9.2 6.4 0.6 2.1 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Hormone_recep PF00104.30 KFO94886.1 - 1.3e-07 31.4 0.0 1.5e-07 31.2 0.0 1.0 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C2H2 PF00096.26 KFO94887.1 - 1.2e-12 47.6 0.8 2e-06 27.9 0.2 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO94887.1 - 1.6e-09 37.8 0.9 0.00091 19.9 0.2 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFO94887.1 - 3.7e-09 36.6 2.1 7.3e-08 32.5 0.5 2.1 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_11 PF16622.5 KFO94887.1 - 0.00034 20.3 2.3 0.044 13.5 0.1 2.2 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-met PF12874.7 KFO94887.1 - 0.00073 19.8 0.5 1.1 9.8 0.0 2.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFO94887.1 - 0.00094 19.4 0.0 0.88 9.9 0.0 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFO94887.1 - 0.00099 18.7 0.1 0.039 13.6 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 KFO94887.1 - 0.0012 18.8 3.0 0.38 10.8 0.2 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-LYAR PF08790.11 KFO94887.1 - 0.0052 16.7 0.8 0.13 12.2 0.1 2.1 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-ribbon_3 PF13248.6 KFO94887.1 - 0.01 15.2 4.6 0.099 12.1 0.6 2.5 2 1 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 KFO94887.1 - 0.024 14.5 0.7 0.11 12.5 0.2 2.0 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 KFO94887.1 - 0.025 14.7 2.0 0.14 12.3 2.1 1.9 1 1 1 2 2 2 0 Zinc ribbon domain XPA_N PF01286.18 KFO94887.1 - 0.027 14.5 0.8 0.77 9.8 0.2 2.1 2 0 0 2 2 2 0 XPA protein N-terminal zinc_ribbon_9 PF14369.6 KFO94887.1 - 0.072 13.4 2.6 1.9 8.8 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon zf-H2C2_5 PF13909.6 KFO94887.1 - 1.1 9.1 5.7 2.7 7.9 0.1 2.8 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-Paramyx-P PF13008.7 KFO94887.1 - 3.4 7.2 7.5 0.34 10.4 3.4 1.5 2 0 0 2 2 2 0 Zinc-binding domain of Paramyxoviridae V protein Pkinase_Tyr PF07714.17 KFO94888.1 - 2.9e-24 85.8 0.0 3.3e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO94888.1 - 6.4e-09 35.5 0.0 6.7e-09 35.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 KFO94888.1 - 0.11 11.4 0.0 0.13 11.2 0.0 1.0 1 0 0 1 1 1 0 Haspin like kinase domain RVT_1 PF00078.27 KFO94889.1 - 2.1e-29 102.7 0.0 2.5e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.26 KFO94890.1 - 6.1e-07 29.5 11.3 7.2e-05 23.0 1.2 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KFO94890.1 - 6.1e-05 22.7 0.5 6.1e-05 22.7 0.5 2.1 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KFO94890.1 - 0.00054 20.6 10.2 0.0026 18.5 1.2 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFO94890.1 - 0.00066 20.0 3.7 0.00066 20.0 3.7 2.7 3 0 0 3 3 3 1 Zinc-finger double domain XPA_N PF01286.18 KFO94890.1 - 0.005 16.9 0.3 0.078 13.0 0.1 2.1 2 0 0 2 2 2 1 XPA protein N-terminal Zn-ribbon_8 PF09723.10 KFO94890.1 - 0.014 15.4 1.1 0.11 12.6 0.4 2.0 1 1 1 2 2 2 0 Zinc ribbon domain DUF2256 PF10013.9 KFO94890.1 - 0.061 13.4 0.1 2 8.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-LYAR PF08790.11 KFO94890.1 - 0.075 12.9 2.0 0.87 9.5 0.0 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-H2C2_2 PF13465.6 KFO94892.1 - 2.6e-08 33.9 4.8 0.00013 22.2 0.5 2.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFO94892.1 - 9.2e-06 25.8 0.1 9.2e-06 25.8 0.1 1.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type Cys_rich_CPXG PF14255.6 KFO94892.1 - 0.0006 19.7 0.3 0.00066 19.5 0.3 1.1 1 0 0 1 1 1 1 Cysteine-rich CPXCG zf-C2H2_4 PF13894.6 KFO94892.1 - 0.00072 20.2 0.1 0.00072 20.2 0.1 1.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.12 KFO94892.1 - 0.0084 16.4 2.9 0.021 15.1 2.9 1.7 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 KFO94892.1 - 0.015 15.0 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 zinc-finger C2H2-type FANCL_C PF11793.8 KFO94892.1 - 0.034 14.3 1.0 0.39 10.9 0.0 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C2HE PF16278.5 KFO94892.1 - 0.04 14.4 0.0 0.047 14.1 0.0 1.1 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_10 PF18414.1 KFO94892.1 - 0.39 10.3 5.2 0.63 9.6 0.3 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger zf-H2C2_5 PF13909.6 KFO94892.1 - 1 9.2 0.1 1 9.2 0.1 3.1 3 1 0 3 3 3 0 C2H2-type zinc-finger domain 7tm_4 PF13853.6 KFO94893.1 - 1.1e-09 38.4 0.4 1.3e-09 38.2 0.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO94893.1 - 7.9e-06 25.4 0.1 9.9e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CholecysA-Rec_N PF09193.10 KFO94893.1 - 0.067 13.2 0.2 0.13 12.3 0.1 1.5 1 1 0 1 1 1 0 Cholecystokinin A receptor, N-terminal zf-H2C2_2 PF13465.6 KFO94895.1 - 3.1e-10 40.0 8.5 4.9e-06 26.7 1.5 2.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFO94895.1 - 8.7e-08 32.2 2.1 1.4e-07 31.6 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KFO94895.1 - 7.3e-07 28.8 0.8 1e-06 28.3 0.8 1.3 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KFO94895.1 - 1.7e-05 25.3 1.5 3e-05 24.5 1.5 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFO94895.1 - 0.0067 16.4 1.4 0.012 15.6 1.4 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFO94895.1 - 0.014 15.5 1.6 0.017 15.2 1.6 1.3 1 1 0 1 1 1 0 Zinc ribbon domain BolA PF01722.18 KFO94895.1 - 0.086 13.1 0.0 0.089 13.1 0.0 1.0 1 0 0 1 1 1 0 BolA-like protein 7tm_4 PF13853.6 KFO94896.1 - 3.6e-11 43.3 0.2 4.2e-11 43.1 0.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO94896.1 - 1.3e-06 28.0 0.1 1.6e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CholecysA-Rec_N PF09193.10 KFO94896.1 - 0.072 13.1 0.1 0.13 12.3 0.1 1.5 1 1 0 1 1 1 0 Cholecystokinin A receptor, N-terminal HU-CCDC81_euk_2 PF18289.1 KFO94898.1 - 8.6e-28 96.3 0.0 1.2e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HU-HIG PF18291.1 KFO94898.1 - 0.095 12.8 0.1 0.41 10.8 0.0 1.8 1 1 0 2 2 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif RVT_1 PF00078.27 KFO94899.1 - 2.1e-28 99.4 0.0 2.8e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 KFO94899.1 - 3.3e-10 39.7 0.1 5.6e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase thumb domain BTB PF00651.31 KFO94900.1 - 9.1e-33 112.8 0.5 3.5e-32 110.9 0.2 1.9 2 0 0 2 2 2 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFO94900.1 - 2.3e-06 27.8 1.0 2.3e-06 27.8 1.0 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-Di19 PF05605.12 KFO94900.1 - 0.016 15.5 0.6 0.035 14.4 0.6 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF2722 PF10846.8 KFO94900.1 - 0.079 11.9 1.6 0.092 11.7 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) zf-C2H2_4 PF13894.6 KFO94900.1 - 0.2 12.6 6.7 0.23 12.4 0.1 3.1 3 0 0 3 3 2 0 C2H2-type zinc finger zf-met PF12874.7 KFO94900.1 - 0.34 11.4 5.1 6.3 7.3 0.5 2.8 3 0 0 3 3 2 0 Zinc-finger of C2H2 type PDDEXK_6 PF04720.12 KFO94900.1 - 0.39 10.6 1.9 0.64 9.9 1.9 1.3 1 0 0 1 1 1 0 PDDEXK-like family of unknown function TFB6 PF17110.5 KFO94900.1 - 0.53 10.0 4.0 0.85 9.3 4.0 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH FAM176 PF14851.6 KFO94900.1 - 0.59 9.8 8.4 1.2 8.8 8.4 1.5 1 0 0 1 1 1 0 FAM176 family zf-C2H2 PF00096.26 KFO94900.1 - 0.59 10.7 0.1 0.59 10.7 0.1 3.4 4 0 0 4 4 2 0 Zinc finger, C2H2 type DUF2457 PF10446.9 KFO94900.1 - 0.68 9.0 16.3 0.96 8.5 16.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PI3K_1B_p101 PF10486.9 KFO94900.1 - 1.4 6.6 4.4 1.9 6.2 4.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nop14 PF04147.12 KFO94900.1 - 2.1 6.5 13.7 2.9 6.0 13.7 1.1 1 0 0 1 1 1 0 Nop14-like family Radial_spoke PF04712.12 KFO94900.1 - 2.4 7.0 8.9 3.5 6.5 8.9 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein CobT PF06213.12 KFO94900.1 - 2.5 7.4 10.1 3.7 6.9 10.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sporozoite_P67 PF05642.11 KFO94900.1 - 3.2 5.7 6.0 4.1 5.4 6.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SDA1 PF05285.12 KFO94900.1 - 3.3 7.1 12.5 5 6.5 12.5 1.2 1 0 0 1 1 1 0 SDA1 PTPRCAP PF15713.5 KFO94900.1 - 7.5 6.8 12.9 14 6.0 12.9 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated RRN3 PF05327.11 KFO94900.1 - 8.5 4.8 11.7 12 4.3 11.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Keratin PF02422.16 KFO94902.1 - 2.4e-40 136.1 16.3 2.7e-40 136.0 16.3 1.0 1 0 0 1 1 1 1 Keratin RVT_1 PF00078.27 KFO94903.1 - 7.3e-19 68.2 0.0 1e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 KFO94903.1 - 1.2e-12 47.4 0.3 2.1e-12 46.7 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase thumb domain zf-H2C2_2 PF13465.6 KFO94904.1 - 1e-11 44.7 7.5 6.2e-10 39.1 1.1 2.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFO94904.1 - 3.8e-10 39.6 6.9 3.8e-07 30.2 0.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO94904.1 - 3.7e-07 30.4 6.1 9.4e-05 22.9 0.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO94904.1 - 1.1e-05 25.5 1.2 0.008 16.4 0.0 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFO94904.1 - 0.00044 20.5 0.2 0.00064 20.0 0.2 1.3 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 KFO94904.1 - 0.0012 18.4 0.9 0.25 11.0 0.2 2.1 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 KFO94904.1 - 0.0013 18.7 6.7 0.23 11.5 2.4 2.3 2 1 0 2 2 2 2 C2H2-type zinc finger DUF2256 PF10013.9 KFO94904.1 - 0.0029 17.7 1.9 1.1 9.5 0.2 2.1 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2256) zf-ribbon_3 PF13248.6 KFO94904.1 - 0.0036 16.7 3.6 0.32 10.5 0.3 2.2 2 0 0 2 2 2 2 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 KFO94904.1 - 0.0053 16.7 4.0 0.0072 16.3 4.0 1.2 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-met PF12874.7 KFO94904.1 - 0.0086 16.4 3.3 0.29 11.6 0.1 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF3268 PF11672.8 KFO94904.1 - 0.0089 16.3 0.4 0.0099 16.2 0.4 1.0 1 0 0 1 1 1 1 zinc-finger-containing domain Zn-ribbon_8 PF09723.10 KFO94904.1 - 0.0091 16.1 2.4 0.83 9.8 0.7 2.1 1 1 0 1 1 1 1 Zinc ribbon domain IBR PF01485.21 KFO94904.1 - 0.016 15.4 1.6 0.02 15.1 1.6 1.2 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain YhfH PF14149.6 KFO94904.1 - 0.016 15.2 1.4 0.43 10.6 0.2 2.1 2 0 0 2 2 2 0 YhfH-like protein LIM PF00412.22 KFO94904.1 - 0.017 15.3 0.4 0.026 14.8 0.4 1.4 1 1 0 1 1 1 0 LIM domain Prok-RING_1 PF14446.6 KFO94904.1 - 0.017 15.0 0.3 3 7.8 0.0 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-BED PF02892.15 KFO94904.1 - 0.018 15.0 1.5 0.66 10.0 0.0 2.1 1 1 1 2 2 2 0 BED zinc finger zf-trcl PF13451.6 KFO94904.1 - 0.03 14.2 0.2 0.03 14.2 0.2 1.8 2 0 0 2 2 2 0 Probable zinc-ribbon domain HNH PF01844.23 KFO94904.1 - 0.032 14.4 3.0 1.4 9.2 0.3 2.1 2 0 0 2 2 2 0 HNH endonuclease zinc_ribbon_4 PF13717.6 KFO94904.1 - 0.034 14.1 2.2 0.23 11.4 2.2 1.9 1 1 0 1 1 1 0 zinc-ribbon domain zf-AN1 PF01428.16 KFO94904.1 - 0.042 14.0 4.9 0.14 12.3 0.3 2.1 2 0 0 2 2 2 0 AN1-like Zinc finger PyrI_C PF02748.15 KFO94904.1 - 0.055 13.4 0.3 8.5 6.4 0.0 2.1 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain CpXC PF14353.6 KFO94904.1 - 0.069 13.2 0.5 7.5 6.6 0.0 2.0 1 1 1 2 2 2 0 CpXC protein Cys_rich_CPXG PF14255.6 KFO94904.1 - 0.071 13.0 0.4 0.44 10.5 0.1 1.9 2 0 0 2 2 2 0 Cysteine-rich CPXCG Zn_ribbon_recom PF13408.6 KFO94904.1 - 0.074 13.6 1.8 3.4 8.2 2.0 2.1 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain ADK_lid PF05191.14 KFO94904.1 - 0.14 12.2 2.0 0.31 11.1 2.0 1.6 1 1 0 1 1 1 0 Adenylate kinase, active site lid XPA_N PF01286.18 KFO94904.1 - 0.14 12.2 3.1 0.36 10.9 0.5 2.1 2 0 0 2 2 2 0 XPA protein N-terminal zf-C2HE PF16278.5 KFO94904.1 - 0.16 12.4 2.1 0.72 10.4 0.7 2.0 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 KFO94904.1 - 0.18 11.7 7.0 1.5 8.8 0.7 2.3 2 1 0 2 2 2 0 zinc-finger of a C2HC-type TFIIS_C PF01096.18 KFO94904.1 - 0.22 11.4 3.3 0.88 9.5 0.4 2.2 2 1 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-LYAR PF08790.11 KFO94904.1 - 0.31 11.0 3.1 10 6.1 0.3 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zinc_ribbon_9 PF14369.6 KFO94904.1 - 0.31 11.3 7.1 5.3 7.4 2.6 2.2 2 0 0 2 2 2 0 zinc-ribbon zinc_ribbon_2 PF13240.6 KFO94904.1 - 0.37 10.6 10.4 1.9 8.3 1.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_7 PF02591.15 KFO94904.1 - 0.49 10.6 5.0 2 8.7 0.2 2.1 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf-CHCC PF10276.9 KFO94904.1 - 0.98 9.5 6.0 8.3 6.6 2.7 2.1 2 0 0 2 2 2 0 Zinc-finger domain zf-H2C2_5 PF13909.6 KFO94904.1 - 1.3 8.8 8.4 5.6 6.8 0.5 3.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain ELM2 PF01448.24 KFO94905.1 - 1e-07 32.6 0.1 1.7e-07 31.9 0.1 1.4 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-bind_7 PF15963.5 KFO94905.1 - 0.0029 17.5 0.2 0.0071 16.2 0.1 1.7 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KFO94905.1 - 0.0051 17.0 0.0 0.0091 16.2 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain RRM_1 PF00076.22 KFO94906.1 - 7.1e-34 115.5 0.1 3.2e-17 62.1 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFO94906.1 - 4.5e-07 29.5 0.0 1.9e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFO94906.1 - 3.1e-06 27.2 0.0 0.0046 17.1 0.0 2.6 2 1 1 3 3 3 2 RNA recognition motif RNA_bind PF08675.11 KFO94906.1 - 0.00085 19.3 0.0 0.17 11.9 0.0 2.1 2 0 0 2 2 2 2 RNA binding domain RRM_occluded PF16842.5 KFO94906.1 - 0.0083 16.0 0.0 2.9 7.8 0.0 2.5 1 1 1 2 2 2 2 Occluded RNA-recognition motif Calcipressin PF04847.12 KFO94906.1 - 0.02 14.6 0.1 0.32 10.7 0.0 2.0 1 1 0 2 2 2 0 Calcipressin DbpA PF03880.15 KFO94906.1 - 0.1 12.6 0.1 2.5 8.1 0.0 2.2 2 0 0 2 2 2 0 DbpA RNA binding domain Nup35_RRM_2 PF14605.6 KFO94906.1 - 0.13 12.3 0.1 0.56 10.3 0.0 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif zf-H2C2_2 PF13465.6 KFO94907.1 - 1.3e-11 44.4 9.0 2.5e-06 27.7 0.6 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFO94907.1 - 8.5e-09 35.4 15.7 0.00016 21.9 1.1 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO94907.1 - 3.9e-06 27.2 14.8 0.0093 16.7 1.2 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFO94907.1 - 0.00079 19.5 1.5 0.00079 19.5 1.5 2.2 1 1 0 2 2 2 1 Zinc ribbon domain C1_4 PF07975.12 KFO94907.1 - 0.0021 18.2 3.3 0.0021 18.2 3.3 2.0 1 1 1 2 2 2 1 TFIIH C1-like domain zf_UBZ PF18439.1 KFO94907.1 - 0.0035 16.9 8.8 0.21 11.2 0.4 3.2 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger DUF3268 PF11672.8 KFO94907.1 - 0.011 16.1 2.7 0.015 15.6 0.6 1.8 1 1 1 2 2 2 0 zinc-finger-containing domain Prok-RING_1 PF14446.6 KFO94907.1 - 0.061 13.3 7.0 0.23 11.4 0.2 2.9 1 1 1 3 3 3 0 Prokaryotic RING finger family 1 Yippee-Mis18 PF03226.14 KFO94907.1 - 0.073 13.3 3.4 0.12 12.6 3.4 1.4 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C4_ClpX PF06689.13 KFO94907.1 - 0.074 13.0 2.6 5.4 7.0 0.8 2.2 2 0 0 2 2 2 0 ClpX C4-type zinc finger zf-C2H2_jaz PF12171.8 KFO94907.1 - 0.092 13.1 8.0 0.16 12.3 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_9 PF14369.6 KFO94907.1 - 0.1 12.9 0.4 0.1 12.9 0.4 3.0 2 1 1 3 3 3 0 zinc-ribbon LIM PF00412.22 KFO94907.1 - 0.14 12.4 6.6 2.1 8.7 0.5 2.6 1 1 1 2 2 2 0 LIM domain zinc_ribbon_15 PF17032.5 KFO94907.1 - 0.15 12.8 4.9 0.15 12.8 0.8 2.0 1 1 1 2 2 2 0 zinc-ribbon family PhnA_Zn_Ribbon PF08274.12 KFO94907.1 - 0.18 11.8 3.3 29 4.7 0.0 3.1 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Zn_Tnp_IS1595 PF12760.7 KFO94907.1 - 0.19 11.8 9.9 0.089 12.8 2.8 2.2 1 1 0 2 2 2 0 Transposase zinc-ribbon domain Pox_A3L PF05288.11 KFO94907.1 - 0.2 11.7 2.0 4.6 7.3 0.0 2.4 3 0 0 3 3 3 0 Poxvirus A3L Protein Zn_ribbon_SprT PF17283.2 KFO94907.1 - 0.2 11.6 7.0 0.39 10.7 1.2 2.5 2 1 0 2 2 2 0 SprT-like zinc ribbon domain HypA PF01155.19 KFO94907.1 - 0.22 11.5 5.0 1.8 8.6 5.0 2.0 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-LYAR PF08790.11 KFO94907.1 - 0.25 11.3 15.1 0.26 11.2 0.2 3.0 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2H2_11 PF16622.5 KFO94907.1 - 0.25 11.1 0.5 0.25 11.1 0.5 2.8 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-AN1 PF01428.16 KFO94907.1 - 0.31 11.2 12.5 3.9 7.7 0.3 3.2 2 1 1 3 3 3 0 AN1-like Zinc finger XPA_N PF01286.18 KFO94907.1 - 0.34 11.0 0.4 0.34 11.0 0.4 3.0 3 0 0 3 3 3 0 XPA protein N-terminal CxC7 PF18866.1 KFO94907.1 - 0.47 10.6 6.2 10 6.3 6.1 2.6 1 1 0 1 1 1 0 CxC7 like cysteine cluster associated with KDZ transposases zinc_ribbon_5 PF13719.6 KFO94907.1 - 0.64 9.8 9.0 3 7.7 3.7 2.7 2 1 0 2 2 2 0 zinc-ribbon domain zf-met PF12874.7 KFO94907.1 - 0.69 10.4 8.5 2.5 8.6 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DZR PF12773.7 KFO94907.1 - 0.7 10.0 8.0 5.9 7.0 8.0 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-trcl PF13451.6 KFO94907.1 - 0.97 9.4 11.7 3.9 7.4 0.3 3.1 2 1 0 3 3 3 0 Probable zinc-ribbon domain TFIIS_C PF01096.18 KFO94907.1 - 1.9 8.4 9.1 20 5.2 0.1 3.2 3 1 0 3 3 3 0 Transcription factor S-II (TFIIS) zinc_ribbon_4 PF13717.6 KFO94907.1 - 2.2 8.3 10.6 16 5.5 0.5 3.0 2 1 0 2 2 2 0 zinc-ribbon domain zf-Paramyx-P PF13008.7 KFO94907.1 - 3.5 7.2 8.6 12 5.5 0.1 2.9 3 0 0 3 3 3 0 Zinc-binding domain of Paramyxoviridae V protein zf-C2H2 PF00096.26 KFO94908.1 - 1.5e-10 41.0 9.3 5.3e-07 29.8 0.6 2.3 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO94908.1 - 1.7e-06 28.3 7.0 0.0002 22.0 0.4 2.2 2 1 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFO94908.1 - 4.8e-06 26.8 0.6 4.8e-06 26.8 0.6 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFO94908.1 - 0.00017 21.2 0.4 0.00017 21.2 0.4 2.7 3 1 0 3 3 3 1 C2H2-type zinc-finger domain zinc_ribbon_9 PF14369.6 KFO94908.1 - 0.00071 19.8 2.0 0.21 11.9 0.5 2.1 2 0 0 2 2 2 2 zinc-ribbon zf-C2H2_11 PF16622.5 KFO94908.1 - 0.01 15.6 0.2 0.01 15.6 0.2 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-Di19 PF05605.12 KFO94908.1 - 0.032 14.5 0.9 0.079 13.3 0.9 1.8 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF1610 PF07754.11 KFO94908.1 - 7.5 6.6 8.7 6.3 6.9 5.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) V-set PF07686.17 KFO94909.1 - 0.00031 20.9 0.0 0.00036 20.7 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Synaptobrevin PF00957.21 KFO94910.1 - 9e-22 76.7 0.5 9.4e-22 76.6 0.5 1.0 1 0 0 1 1 1 1 Synaptobrevin Integrase_H2C2 PF17921.1 KFO94910.1 - 0.17 12.1 0.4 0.17 12.0 0.4 1.3 1 1 0 1 1 1 0 Integrase zinc binding domain Lectin_C PF00059.21 KFO94911.1 - 0.00022 21.9 0.3 0.0005 20.8 0.0 1.6 1 1 1 2 2 2 1 Lectin C-type domain hNIFK_binding PF12196.8 KFO94912.1 - 0.048 13.2 0.1 0.071 12.6 0.1 1.3 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK Dymeclin PF09742.9 KFO94913.1 - 2.6e-10 39.4 0.5 2.7e-10 39.3 0.5 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DUF4512 PF14975.6 KFO94915.1 - 3.3e-17 63.1 1.7 3.3e-17 63.0 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4512) Clat_adaptor_s PF01217.20 KFO94916.1 - 1.7e-17 63.7 0.3 1.8e-17 63.6 0.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Trypsin PF00089.26 KFO94917.1 - 2.5e-14 53.6 0.0 2.5e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 Trypsin SET PF00856.28 KFO94918.1 - 1e-13 52.0 0.0 1.1e-13 51.9 0.0 1.0 1 0 0 1 1 1 1 SET domain HAD_2 PF13419.6 KFO94919.1 - 0.00098 19.3 0.0 0.00098 19.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFO94919.1 - 0.0058 16.9 0.0 0.0058 16.9 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HRG PF16954.5 KFO94920.1 - 5.2e-07 30.0 8.5 1.7e-06 28.3 1.1 2.0 2 0 0 2 2 2 2 Haem-transporter, endosomal/lysosomal, haem-responsive gene Col_cuticle_N PF01484.17 KFO94920.1 - 0.039 14.0 0.2 9.2 6.4 0.6 2.1 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain zf-C2H2_4 PF13894.6 KFO94921.1 - 4.5e-06 27.1 4.9 0.033 15.0 1.4 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFO94921.1 - 0.00011 22.5 3.6 0.014 15.8 0.9 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_9 PF16293.5 KFO94921.1 - 0.00018 21.3 4.4 0.11 12.4 0.4 2.1 2 0 0 2 2 2 2 C2H2 type zinc-finger (1 copy) zf-C2H2_jaz PF12171.8 KFO94921.1 - 0.0012 19.1 3.5 0.62 10.4 0.0 2.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFO94921.1 - 0.0047 17.2 1.5 1.3 9.4 0.2 2.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFO94921.1 - 0.013 15.9 3.8 0.8 10.2 0.2 2.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KFO94921.1 - 0.056 13.9 9.3 0.16 12.4 2.3 2.9 3 0 0 3 3 3 0 Zinc-finger double domain Baculo_IE-1 PF05290.11 KFO94921.1 - 0.082 12.9 1.0 0.082 12.9 1.0 1.5 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) FOXP-CC PF16159.5 KFO94921.1 - 0.09 13.4 1.1 4.3 8.1 0.1 2.0 1 1 1 2 2 2 0 FOXP coiled-coil domain DUF629 PF04780.12 KFO94921.1 - 0.38 9.2 4.0 1.3 7.5 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_12 PF18658.1 KFO94921.1 - 1.4 8.6 5.3 1.5 8.4 0.8 2.1 1 1 1 2 2 2 0 Zinc-finger C2H2-type CX9C PF16860.5 KFO94922.1 - 0.00022 21.2 2.1 0.16 12.0 0.2 2.1 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 KFO94922.1 - 0.00026 21.0 7.2 0.00035 20.6 7.2 1.3 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 KFO94922.1 - 0.0063 16.5 4.7 0.2 11.7 1.0 2.0 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like DB PF01682.19 KFO94922.1 - 0.0098 16.2 1.4 0.01 16.1 1.4 1.1 1 0 0 1 1 1 1 DB module COX17 PF05051.13 KFO94922.1 - 0.023 15.0 3.2 0.027 14.8 3.2 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) DUF3128 PF11326.8 KFO94922.1 - 0.033 14.6 3.1 1.8 9.0 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) ANF_receptor PF01094.28 KFO94923.1 - 7.4e-11 41.7 0.0 8.2e-11 41.6 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region BAF PF02961.14 KFO94924.1 - 1.8e-21 76.4 0.5 1.9e-21 76.3 0.5 1.0 1 0 0 1 1 1 1 Barrier to autointegration factor Defensin_beta PF00711.19 KFO94926.1 - 1.3e-10 41.1 8.2 1.5e-10 40.9 8.2 1.1 1 0 0 1 1 1 1 Beta defensin Polysacc_synt_4 PF04669.13 KFO94927.1 - 0.0004 20.0 0.0 0.00041 20.0 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis Ras PF00071.22 KFO94928.1 - 7.9e-42 142.6 0.0 8.7e-42 142.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO94928.1 - 3.2e-10 40.3 0.0 4.2e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KFO94928.1 - 1.4e-05 24.7 0.0 4.9e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KFO94928.1 - 1.7e-05 24.3 0.0 1.7e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFO94928.1 - 0.0037 17.2 0.0 0.0042 17.0 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KFO94928.1 - 0.018 15.1 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 KFO94928.1 - 0.028 13.9 0.0 0.031 13.8 0.0 1.4 1 1 0 1 1 1 0 Ferrous iron transport protein B COG2 PF06148.11 KFO94929.1 - 0.0057 16.7 0.9 0.0062 16.6 0.9 1.0 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF4085 PF13315.6 KFO94929.1 - 0.0093 15.6 0.2 0.011 15.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4085) DUF5082 PF16888.5 KFO94929.1 - 0.015 15.6 1.8 0.019 15.2 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Spc29 PF17082.5 KFO94929.1 - 0.023 14.5 0.2 0.024 14.5 0.2 1.0 1 0 0 1 1 1 0 Spindle Pole Component 29 Sec2p PF06428.11 KFO94929.1 - 0.024 14.6 1.9 0.026 14.5 1.9 1.1 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p AGTRAP PF06396.11 KFO94930.1 - 2e-27 95.8 0.1 2.2e-27 95.7 0.1 1.0 1 0 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) DUF4199 PF13858.6 KFO94930.1 - 0.11 12.8 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Tubulin PF00091.25 KFO94931.1 - 1.3e-09 38.6 0.0 1.4e-09 38.5 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain GPP34 PF05719.11 KFO94932.1 - 7.6e-16 58.8 0.3 8.7e-16 58.6 0.3 1.0 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Peptidase_M15_2 PF05951.13 KFO94932.1 - 0.053 13.2 0.1 0.085 12.5 0.1 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF882) C1-set PF07654.15 KFO94933.1 - 1.7e-23 82.8 0.1 1.9e-23 82.6 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.6 KFO94933.1 - 6.1e-05 23.5 0.0 6.8e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFO94933.1 - 0.00096 19.3 0.1 0.0012 19.0 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFO94933.1 - 0.0056 17.0 0.0 0.0075 16.6 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFO94933.1 - 0.014 15.4 0.1 0.018 15.1 0.1 1.1 1 0 0 1 1 1 0 Immunoglobulin I-set domain Marek_A PF02124.15 KFO94933.1 - 0.026 14.3 0.0 0.03 14.2 0.0 1.0 1 0 0 1 1 1 0 Marek's disease glycoprotein A PTH2 PF01981.16 KFO94934.1 - 1.2e-48 164.2 0.0 1.3e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF2000 PF09391.10 KFO94934.1 - 0.022 14.7 0.4 0.6 10.0 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2000) Rsm22 PF09243.10 KFO94934.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 zf-RING_UBOX PF13445.6 KFO94935.1 - 4.8e-09 36.1 8.0 4.8e-09 36.1 8.0 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFO94935.1 - 8.6e-08 32.4 11.4 1.9e-07 31.3 11.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFO94935.1 - 9.3e-07 28.7 11.1 9.3e-07 28.7 11.1 1.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFO94935.1 - 4.9e-05 23.1 11.6 0.00011 22.0 11.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KFO94935.1 - 0.0004 20.4 5.6 0.0004 20.4 5.6 1.6 2 0 0 2 2 2 1 FYVE zinc finger zf-C3HC4_2 PF13923.6 KFO94935.1 - 0.00063 19.5 13.7 0.0061 16.4 13.7 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFO94935.1 - 0.0066 16.2 5.7 0.0066 16.2 5.7 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_4 PF14570.6 KFO94935.1 - 0.012 15.4 7.6 0.024 14.4 7.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain GAGA PF09237.11 KFO94935.1 - 0.034 14.0 1.9 4.2 7.3 0.1 2.3 2 0 0 2 2 2 0 GAGA factor Prok-RING_4 PF14447.6 KFO94935.1 - 0.05 13.5 14.3 1.8 8.5 14.4 2.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 FYVE_2 PF02318.16 KFO94935.1 - 0.12 12.6 4.2 0.12 12.6 3.0 1.5 2 0 0 2 2 2 0 FYVE-type zinc finger zf-C3HC4_4 PF15227.6 KFO94935.1 - 0.19 11.9 14.6 2.3 8.5 14.5 2.6 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Zn-C2H2_12 PF18112.1 KFO94935.1 - 0.24 11.9 7.4 1.1 9.7 1.6 2.7 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Bile_Hydr_Trans PF04775.14 KFO94936.1 - 2.6e-38 130.9 0.0 2.9e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region UPAR_LY6 PF00021.21 KFO94937.1 - 0.0057 17.3 0.6 0.0079 16.9 0.6 1.2 1 0 0 1 1 1 1 u-PAR/Ly-6 domain BAMBI PF06211.12 KFO94937.1 - 0.0076 16.5 0.6 0.0094 16.2 0.6 1.2 1 0 0 1 1 1 1 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Toxin_TOLIP PF00087.21 KFO94937.1 - 0.016 15.5 1.6 0.024 14.9 1.6 1.3 1 0 0 1 1 1 0 Snake toxin and toxin-like protein p450 PF00067.22 KFO94938.1 - 3.5e-13 49.1 0.1 3.5e-13 49.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 EF-hand_6 PF13405.6 KFO94942.1 - 4.5e-10 38.6 2.9 3.5e-08 32.7 0.9 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 KFO94942.1 - 1.3e-09 38.4 0.4 4.5e-08 33.4 0.1 2.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KFO94942.1 - 3.5e-08 32.4 9.0 5.9e-08 31.7 1.6 3.7 5 0 0 5 5 5 1 EF hand EF-hand_5 PF13202.6 KFO94942.1 - 9.1e-06 24.9 1.6 9.1e-06 24.9 1.6 2.4 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 KFO94942.1 - 1.2e-05 25.0 6.0 0.0012 18.6 0.7 3.1 1 1 2 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFO94942.1 - 0.043 14.1 0.2 0.056 13.8 0.2 1.2 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2666 PF10869.8 KFO94942.1 - 0.11 12.7 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) DUF3741 PF12552.8 KFO94942.1 - 0.12 12.3 1.3 0.13 12.2 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3741) DUF4792 PF16040.5 KFO94943.1 - 0.036 14.0 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4792) DUF4364 PF14277.6 KFO94944.1 - 0.094 12.5 0.0 0.094 12.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) Proteasome PF00227.26 KFO94946.1 - 6.8e-15 55.0 0.0 7.3e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Ferlin_C PF16165.5 KFO94947.1 - 2e-14 53.8 2.4 2.3e-06 27.6 0.1 2.2 1 1 1 2 2 2 2 Ferlin C-terminus Pkinase PF00069.25 KFO94948.1 - 1.6e-05 24.4 0.0 1.6e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Nop14 PF04147.12 KFO94949.1 - 9.4 4.3 30.0 11 4.1 30.0 1.0 1 0 0 1 1 1 0 Nop14-like family MCCD1 PF15707.5 KFO94950.1 - 0.012 16.0 3.4 0.015 15.7 3.4 1.3 1 0 0 1 1 1 0 Mitochondrial coiled-coil domain protein 1 Fmp27_WPPW PF10359.9 KFO94950.1 - 0.057 12.3 2.5 0.059 12.2 2.5 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain 7tm_1 PF00001.21 KFO94951.1 - 2.2e-20 73.1 2.9 2.6e-20 72.8 2.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SH2 PF00017.24 KFO94952.1 - 1.3e-06 28.4 0.1 2e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 SH2 domain HIG_1_N PF04588.13 KFO94953.1 - 4.1e-13 49.3 2.1 4.5e-13 49.2 2.1 1.0 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF5353 PF17304.2 KFO94953.1 - 0.13 12.1 0.9 0.17 11.7 0.9 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5353) LIM PF00412.22 KFO94954.1 - 1.4e-16 60.4 9.0 1.6e-16 60.3 9.0 1.0 1 0 0 1 1 1 1 LIM domain C1_4 PF07975.12 KFO94954.1 - 0.014 15.6 7.8 0.019 15.2 7.8 1.3 1 1 0 1 1 1 0 TFIIH C1-like domain Vps39_2 PF10367.9 KFO94954.1 - 0.55 10.7 5.2 0.24 11.9 0.7 2.0 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 Trypsin PF00089.26 KFO94955.1 - 7e-18 65.2 1.5 7.5e-18 65.1 1.5 1.0 1 0 0 1 1 1 1 Trypsin Folate_carrier PF01770.18 KFO94958.1 - 8.6e-103 344.2 4.6 9.6e-103 344.1 4.6 1.0 1 0 0 1 1 1 1 Reduced folate carrier MFS_1 PF07690.16 KFO94958.1 - 1.1e-09 37.8 5.6 1.3e-09 37.5 5.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4395 PF14340.6 KFO94958.1 - 0.66 10.3 9.8 1.5 9.2 9.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4395) dUTPase PF00692.19 KFO94959.1 - 9.5e-20 70.6 0.0 1.4e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 dUTPase RVP PF00077.20 KFO94959.1 - 0.0051 17.1 0.1 0.011 16.0 0.1 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KFO94959.1 - 0.036 14.7 0.1 0.23 12.1 0.1 2.2 2 0 0 2 2 2 0 Aspartyl protease Trypsin PF00089.26 KFO94960.1 - 3.8e-17 62.8 2.6 4.1e-17 62.7 2.6 1.0 1 0 0 1 1 1 1 Trypsin Pkinase PF00069.25 KFO94961.1 - 3e-05 23.5 0.0 3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain AAA_lid_6 PF17866.1 KFO94961.1 - 0.12 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA lid domain Filament PF00038.21 KFO94962.1 - 7.4e-49 167.0 5.1 8.1e-49 166.9 5.1 1.0 1 0 0 1 1 1 1 Intermediate filament protein Bacillus_HBL PF05791.11 KFO94962.1 - 0.00081 19.3 2.2 0.001 19.0 1.3 1.5 1 1 1 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) DUF5344 PF17279.2 KFO94962.1 - 0.0011 19.5 2.0 0.51 10.9 0.9 2.3 2 0 0 2 2 2 2 Family of unknown function (DUF5344) Leu_zip PF15294.6 KFO94962.1 - 0.0069 15.9 3.3 0.0098 15.4 3.3 1.3 1 0 0 1 1 1 1 Leucine zipper Sec2p PF06428.11 KFO94962.1 - 0.014 15.4 6.5 0.21 11.6 0.1 2.5 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Prefoldin PF02996.17 KFO94962.1 - 0.014 15.3 4.9 0.95 9.4 0.7 3.0 2 1 1 3 3 3 0 Prefoldin subunit TPR_MLP1_2 PF07926.12 KFO94962.1 - 0.021 14.9 10.9 0.066 13.3 10.3 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.12 KFO94962.1 - 0.024 14.7 3.0 1.8 8.6 2.7 2.7 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4924 PF16271.5 KFO94962.1 - 0.029 14.4 0.8 0.041 13.9 0.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4924) DUF4407 PF14362.6 KFO94962.1 - 0.078 12.3 4.8 0.12 11.7 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HalX PF08663.10 KFO94962.1 - 0.082 13.2 0.8 0.082 13.2 0.8 2.9 1 1 2 3 3 3 0 HalX domain Terminase_6C PF17289.2 KFO94962.1 - 0.092 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Terminase RNaseH-like domain SDH_beta PF03315.15 KFO94962.1 - 0.094 13.1 0.2 0.15 12.4 0.1 1.4 1 1 0 1 1 1 0 Serine dehydratase beta chain Fib_alpha PF08702.10 KFO94962.1 - 0.14 12.3 5.3 1.4 9.1 2.0 2.1 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Atg14 PF10186.9 KFO94962.1 - 0.15 11.2 5.5 0.19 10.8 5.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 KFO94962.1 - 0.15 12.1 6.4 0.2 11.7 6.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 KFO94962.1 - 0.18 11.9 2.7 0.56 10.3 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SlyX PF04102.12 KFO94962.1 - 0.23 12.1 11.7 1.8 9.2 1.0 3.1 2 1 1 3 3 3 0 SlyX SOGA PF11365.8 KFO94962.1 - 0.28 12.3 6.2 0.76 10.9 1.9 2.1 1 1 1 2 2 2 0 Protein SOGA ADIP PF11559.8 KFO94962.1 - 0.38 10.8 9.4 4.2 7.4 7.5 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding COMP PF11598.8 KFO94962.1 - 0.38 11.3 6.2 6.9 7.2 0.6 3.6 3 1 0 3 3 3 0 Cartilage oligomeric matrix protein FapA PF03961.13 KFO94962.1 - 0.53 8.8 4.2 0.75 8.3 4.2 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A BST2 PF16716.5 KFO94962.1 - 0.77 10.4 7.4 4.6 7.9 1.5 2.5 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 HIP1_clath_bdg PF16515.5 KFO94962.1 - 0.88 10.2 10.3 0.31 11.7 6.4 1.9 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Csm1_N PF18504.1 KFO94962.1 - 1.1 9.7 10.5 0.51 10.7 1.2 3.0 2 1 1 3 3 3 0 Csm1 N-terminal domain TolA_bind_tri PF16331.5 KFO94962.1 - 3.5 7.8 17.8 0.21 11.7 1.6 3.5 3 1 1 4 4 3 0 TolA binding protein trimerisation APG6_N PF17675.1 KFO94962.1 - 3.9 8.0 11.6 5.6 7.5 11.6 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region FlaC_arch PF05377.11 KFO94962.1 - 6.1 7.3 6.4 18 5.8 2.1 2.6 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) Trypsin PF00089.26 KFO94964.1 - 2.4e-19 70.0 1.2 2.6e-19 69.9 1.2 1.0 1 0 0 1 1 1 1 Trypsin Zona_pellucida PF00100.23 KFO94965.1 - 0.0005 19.9 0.7 0.00053 19.9 0.7 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain YEATS PF03366.16 KFO94965.1 - 0.072 13.1 0.0 0.088 12.8 0.0 1.2 1 0 0 1 1 1 0 YEATS family Homeodomain PF00046.29 KFO94966.1 - 4e-12 45.8 1.1 4.8e-12 45.6 1.1 1.1 1 0 0 1 1 1 1 Homeodomain zf-RING_2 PF13639.6 KFO94967.1 - 0.00064 20.0 10.1 0.00064 20.0 10.1 3.6 2 1 0 2 2 2 1 Ring finger domain zf-HC5HC2H PF13771.6 KFO94967.1 - 0.0044 17.2 27.2 0.0096 16.2 11.6 3.6 2 2 0 2 2 2 1 PHD-like zinc-binding domain SOGA PF11365.8 KFO94968.1 - 0.0014 19.8 1.9 0.0016 19.5 1.9 1.1 1 0 0 1 1 1 1 Protein SOGA DUF1664 PF07889.12 KFO94968.1 - 0.022 14.8 1.7 0.025 14.6 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4795 PF16043.5 KFO94968.1 - 0.036 13.7 3.9 0.036 13.7 3.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DivIC PF04977.15 KFO94968.1 - 0.037 13.8 2.4 0.054 13.3 2.3 1.4 1 1 0 1 1 1 0 Septum formation initiator FapA PF03961.13 KFO94968.1 - 0.054 12.1 2.9 0.059 12.0 2.9 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Nas2_N PF18265.1 KFO94968.1 - 0.097 12.6 3.3 0.84 9.6 0.3 2.1 1 1 1 2 2 2 0 Nas2 N_terminal domain Swi5 PF07061.11 KFO94968.1 - 0.13 12.4 4.2 0.14 12.2 4.2 1.1 1 0 0 1 1 1 0 Swi5 DUF4140 PF13600.6 KFO94968.1 - 0.2 12.1 2.5 0.23 11.9 2.5 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) ER_lumen_recept PF00810.18 KFO94969.1 - 7.9e-11 43.0 0.1 8.1e-11 43.0 0.1 1.0 1 0 0 1 1 1 1 ER lumen protein retaining receptor RVT_1 PF00078.27 KFO94970.1 - 2.5e-23 82.8 0.0 2.8e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4763 PF15960.5 KFO94971.1 - 0.0021 17.4 1.5 0.0021 17.4 1.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4763) Lzipper-MIP1 PF14389.6 KFO94971.1 - 0.0046 17.2 7.8 0.32 11.3 3.4 3.1 2 0 0 2 2 2 2 Leucine-zipper of ternary complex factor MIP1 Hrs_helical PF12210.8 KFO94971.1 - 0.066 13.8 8.6 0.2 12.2 1.5 3.3 3 1 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate ACR_tran PF00873.19 KFO94971.1 - 0.21 9.2 0.6 0.23 9.1 0.6 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Cas9_PI2 PF18070.1 KFO94971.1 - 0.87 10.4 3.1 20 6.0 0.3 2.8 2 0 0 2 2 2 0 CRISPR-Cas9 PI domain PHM7_cyt PF14703.6 KFO94971.1 - 1.2 9.4 9.6 0.049 13.9 1.7 2.3 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter HMMR_C PF15908.5 KFO94971.1 - 2.7 8.3 12.5 0.41 10.9 3.0 3.4 3 1 1 4 4 4 0 Hyaluronan mediated motility receptor C-terminal UPF0242 PF06785.11 KFO94971.1 - 3.6 7.7 19.9 6 6.9 8.6 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Jnk-SapK_ap_N PF09744.9 KFO94971.1 - 4.8 7.4 19.2 0.44 10.7 6.0 3.0 2 2 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF724 PF05266.14 KFO94971.1 - 5.6 6.8 13.1 0.11 12.4 4.0 2.5 2 2 0 2 2 2 0 Protein of unknown function (DUF724) ATG16 PF08614.11 KFO94971.1 - 8.3 6.6 20.1 0.3 11.3 11.3 2.3 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) 7tm_2 PF00002.24 KFO94972.1 - 7.5e-16 58.2 8.6 7.7e-16 58.1 8.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) E1-E2_ATPase PF00122.20 KFO94973.1 - 6.5e-14 51.9 2.5 6.9e-14 51.8 2.5 1.0 1 0 0 1 1 1 1 E1-E2 ATPase DUF475 PF04332.15 KFO94973.1 - 0.0092 15.8 2.2 0.011 15.5 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF475) Ion_trans PF00520.31 KFO94974.1 - 0.0039 16.5 0.3 0.004 16.4 0.3 1.0 1 0 0 1 1 1 1 Ion transport protein PsbW PF07123.12 KFO94974.1 - 0.037 14.0 0.3 0.043 13.8 0.3 1.1 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Exo84_C PF16528.5 KFO94976.1 - 5.3e-50 170.1 0.0 6.8e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Exocyst component 84 C-terminal PH PF00169.29 KFO94976.1 - 0.0001 22.7 0.0 0.00017 22.0 0.0 1.4 1 0 0 1 1 1 1 PH domain Dor1 PF04124.12 KFO94976.1 - 0.01 14.5 0.1 0.02 13.6 0.1 1.4 1 1 0 1 1 1 0 Dor1-like family Adeno_terminal PF02459.15 KFO94976.1 - 0.016 13.6 5.0 0.027 12.9 5.0 1.3 1 0 0 1 1 1 0 Adenoviral DNA terminal protein PH_13 PF16652.5 KFO94976.1 - 0.29 10.9 3.0 2.8 7.8 0.6 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain LRR_8 PF13855.6 KFO94978.1 - 2.2e-17 62.5 3.3 1.7e-11 43.7 0.2 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRRNT PF01462.18 KFO94978.1 - 6.2e-09 35.3 3.0 6.2e-09 35.3 3.0 2.1 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.7 KFO94978.1 - 5.5e-08 33.0 8.5 2.5e-05 24.5 0.6 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFO94978.1 - 2.7e-06 27.4 0.1 4.3e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KFO94978.1 - 0.00029 20.6 2.2 0.2 11.8 0.0 3.5 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 KFO94978.1 - 0.00038 20.6 8.3 0.23 12.1 0.2 4.4 4 2 0 4 4 4 2 Leucine Rich Repeat CLTH PF10607.9 KFO94979.1 - 1.3e-21 77.0 1.8 1.5e-21 76.8 1.8 1.0 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LRR_8 PF13855.6 KFO94980.1 - 4.2e-10 39.2 10.0 1.2e-07 31.4 4.0 3.0 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KFO94980.1 - 3.5e-08 33.6 10.3 1.7e-06 28.2 4.3 3.3 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFO94980.1 - 0.0033 17.7 11.4 0.065 13.8 0.6 4.0 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_9 PF14580.6 KFO94980.1 - 0.023 14.2 0.8 0.039 13.5 0.8 1.4 1 1 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 KFO94980.1 - 0.03 14.3 7.9 5.8 7.2 0.6 4.2 4 0 0 4 4 4 0 Leucine Rich repeat 7tm_4 PF13853.6 KFO94981.1 - 4.9e-44 151.1 11.1 6.2e-44 150.8 11.1 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO94981.1 - 9.8e-22 77.5 11.7 1.7e-21 76.8 11.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFO94981.1 - 0.00038 19.9 8.4 0.00068 19.1 7.9 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Parathyroid PF01279.17 KFO94982.1 - 1.5e-07 32.0 1.1 1.9e-07 31.7 1.1 1.2 1 0 0 1 1 1 1 Parathyroid hormone family CENP-L PF13092.6 KFO94984.1 - 3.2e-32 112.0 0.0 3.7e-32 111.8 0.0 1.0 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Ge1_WD40 PF16529.5 KFO94984.1 - 0.066 12.2 0.0 0.081 11.9 0.0 1.2 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SIS PF01380.22 KFO94985.1 - 0.0036 17.2 0.2 0.0058 16.5 0.2 1.4 1 0 0 1 1 1 1 SIS domain Glyco_transf_92 PF01697.27 KFO94985.1 - 0.047 13.3 0.0 0.053 13.2 0.0 1.0 1 0 0 1 1 1 0 Glycosyltransferase family 92 TIR PF01582.20 KFO94986.1 - 1.3e-24 87.0 0.1 2.2e-24 86.2 0.1 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 KFO94986.1 - 1.6e-15 57.7 0.0 4e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.6 KFO94986.1 - 4e-15 55.3 4.8 2.4e-08 33.6 0.3 3.5 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KFO94986.1 - 4.7e-12 45.9 10.1 1e-05 25.8 0.3 4.7 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFO94986.1 - 2.3e-08 33.5 8.4 0.043 13.9 0.3 5.2 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 KFO94986.1 - 5.6e-06 26.2 4.5 2.5 9.0 0.3 5.4 3 2 1 4 4 4 2 Leucine Rich Repeat LRRCT PF01463.24 KFO94986.1 - 3.4e-05 24.1 0.4 0.00016 21.9 0.0 2.5 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain Tmp39 PF10271.9 KFO94986.1 - 0.0044 16.1 0.8 0.88 8.5 0.0 2.3 2 0 0 2 2 2 2 Putative transmembrane protein rve PF00665.26 KFO94988.1 - 3.3e-27 95.1 0.2 1.4e-26 93.0 0.1 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_Zn PF02022.19 KFO94988.1 - 6.2e-15 54.9 0.8 1.5e-14 53.6 0.8 1.7 2 0 0 2 2 2 1 Integrase Zinc binding domain RNase_H PF00075.24 KFO94988.1 - 5e-09 36.5 0.2 1.3e-08 35.2 0.0 1.7 2 0 0 2 2 2 1 RNase H DDE_Tnp_IS240 PF13610.6 KFO94988.1 - 0.0006 20.0 0.0 0.001 19.3 0.0 1.4 1 0 0 1 1 1 1 DDE domain rve_3 PF13683.6 KFO94988.1 - 0.048 13.4 0.0 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain RecR PF02132.15 KFO94988.1 - 0.11 12.1 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 RecR protein IL1 PF00340.19 KFO94989.1 - 1.8e-10 40.5 0.3 2.4e-10 40.1 0.3 1.1 1 0 0 1 1 1 1 Interleukin-1 / 18 QVR PF17064.5 KFO94989.1 - 0.051 13.8 1.0 0.11 12.7 0.5 1.7 1 1 1 2 2 2 0 Sleepless protein BACK PF07707.15 KFO94990.1 - 3e-32 110.8 1.3 3.5e-31 107.4 0.4 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_1 PF01344.25 KFO94990.1 - 2.5e-19 68.6 4.4 4.4e-11 42.2 0.6 2.7 3 0 0 3 3 3 2 Kelch motif BTB PF00651.31 KFO94990.1 - 5.8e-14 52.3 0.1 1.3e-13 51.2 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.6 KFO94990.1 - 6.3e-14 51.7 0.5 3.5e-05 23.9 0.0 3.4 2 1 1 3 3 3 2 Kelch motif Kelch_2 PF07646.15 KFO94990.1 - 5.3e-11 42.0 3.9 2.5e-06 27.2 0.2 2.9 2 1 0 2 2 2 2 Kelch motif Kelch_3 PF13415.6 KFO94990.1 - 1.5e-05 25.1 0.0 0.0069 16.7 0.0 2.4 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_4 PF13418.6 KFO94990.1 - 7.4e-05 22.7 0.0 0.19 11.7 0.0 2.6 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KFO94990.1 - 0.0042 17.0 1.7 23 5.1 0.0 3.5 3 0 0 3 3 3 0 Kelch motif DUF4262 PF14081.6 KFO94990.1 - 0.084 13.1 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4262) p450 PF00067.22 KFO94991.1 - 4.2e-21 75.2 0.1 4.7e-21 75.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1087 PF06465.13 KFO94992.1 - 0.068 13.2 0.5 0.13 12.3 0.2 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1087) Cpn10 PF00166.21 KFO94993.1 - 1e-14 54.4 0.1 1.1e-14 54.3 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit GFA PF04828.14 KFO94994.1 - 0.11 12.9 0.2 2.4 8.6 0.0 2.2 1 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme FAM167 PF11652.8 KFO94995.1 - 1.3e-36 125.0 1.2 1.4e-36 124.8 1.2 1.0 1 0 0 1 1 1 1 FAM167 DUF4132 PF13569.6 KFO94995.1 - 0.14 11.9 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4132) DUF4605 PF15378.6 KFO94996.1 - 7.6e-26 89.7 6.4 7.6e-26 89.7 6.4 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4605) TMEM213 PF15192.6 KFO94997.1 - 6.8e-32 109.3 1.5 7.1e-32 109.2 1.5 1.0 1 0 0 1 1 1 1 TMEM213 family DnaJ PF00226.31 KFO94998.1 - 2.5e-17 62.7 1.4 3.6e-17 62.2 1.4 1.3 1 0 0 1 1 1 1 DnaJ domain Baculo_F PF12259.8 KFO94998.1 - 0.023 13.3 0.0 0.024 13.2 0.0 1.0 1 0 0 1 1 1 0 Baculovirus F protein EMP70 PF02990.16 KFO94998.1 - 0.064 11.9 0.1 0.067 11.9 0.1 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 Corona_S2 PF01601.16 KFO94998.1 - 0.75 8.2 8.0 0.72 8.3 8.0 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Mito_carr PF00153.27 KFO94999.1 - 1.4e-08 34.5 0.0 1.5e-08 34.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein Y_phosphatase PF00102.27 KFO95000.1 - 2.6e-29 102.4 0.0 2.8e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CENP-F_N PF10481.9 KFO95001.1 - 1.7e-33 116.6 11.4 1.9e-33 116.5 11.4 1.0 1 0 0 1 1 1 1 Cenp-F N-terminal domain PuR_N PF09182.10 KFO95001.1 - 0.03 14.2 0.1 0.039 13.9 0.1 1.2 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal RACo_linker PF17650.1 KFO95001.1 - 0.043 13.7 0.1 0.095 12.6 0.1 1.6 1 1 1 2 2 2 0 RACo linker region Calici_MSP PF05752.11 KFO95001.1 - 0.075 12.8 1.8 0.07 13.0 1.8 1.1 1 0 0 1 1 1 0 Calicivirus minor structural protein KxDL PF10241.9 KFO95001.1 - 0.31 11.3 6.2 0.35 11.2 6.2 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein FlaC_arch PF05377.11 KFO95001.1 - 0.56 10.6 7.3 6.2 7.3 2.0 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) HemX PF04375.14 KFO95001.1 - 0.64 9.2 7.7 0.66 9.2 7.7 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF2570 PF10828.8 KFO95001.1 - 1.4 8.7 8.0 1.6 8.6 8.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DivIC PF04977.15 KFO95001.1 - 5.3 6.9 9.2 8.2 6.3 2.7 2.1 1 1 1 2 2 2 0 Septum formation initiator C4 PF01413.19 KFO95002.1 - 1.5e-45 154.1 0.8 6.7e-36 123.0 0.3 2.0 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen C1q PF00386.21 KFO95004.1 - 4.8e-39 133.5 0.0 5.7e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFO95004.1 - 2.7e-10 39.8 34.0 3.8e-10 39.4 34.0 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) BclA_C PF18573.1 KFO95004.1 - 0.0023 17.8 0.0 0.003 17.5 0.0 1.2 1 0 0 1 1 1 1 BclA C-terminal domain zf-CCCH PF00642.24 KFO95005.1 - 2.5e-08 33.6 1.9 4.3e-08 32.9 1.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFO95005.1 - 6.2e-05 22.9 1.4 0.00016 21.6 1.4 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KFO95005.1 - 8.3e-05 22.3 1.0 0.00013 21.7 1.0 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger Glycos_transf_1 PF00534.20 KFO95006.1 - 1.6e-40 138.4 0.0 2.6e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFO95006.1 - 2.9e-18 66.6 0.0 4.2e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFO95006.1 - 3.5e-06 27.1 0.1 8.2e-06 25.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KFO95006.1 - 3.2e-05 24.2 0.0 9.5e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KFO95006.1 - 0.0063 17.0 0.0 0.033 14.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain DUF1796 PF08795.10 KFO95006.1 - 0.063 13.2 0.2 0.57 10.1 0.2 2.4 1 1 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Actin PF00022.19 KFO95007.1 - 4e-34 117.9 0.0 4.3e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Actin MIS13 PF08202.11 KFO95008.1 - 0.067 12.5 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Mis12-Mtw1 protein family LSM PF01423.22 KFO95011.1 - 0.011 15.5 0.1 0.019 14.7 0.1 1.4 1 0 0 1 1 1 0 LSM domain TSSC4 PF15264.6 KFO95012.1 - 1.1e-26 93.5 0.3 2.6e-26 92.3 0.0 1.8 2 0 0 2 2 2 1 Tumour suppressing sub-chromosomal transferable candidate 4 ATP-synt_C PF00137.21 KFO95013.1 - 3.3e-10 40.2 10.3 3.9e-10 39.9 10.3 1.1 1 0 0 1 1 1 1 ATP synthase subunit C 7tm_4 PF13853.6 KFO95014.1 - 2.8e-54 184.7 12.1 3.3e-54 184.5 12.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO95014.1 - 1.1e-27 97.1 16.0 1.4e-27 96.7 16.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ig_2 PF13895.6 KFO95016.1 - 2.4e-08 34.2 0.0 3.2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFO95016.1 - 4.9e-08 33.4 0.0 7.1e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFO95016.1 - 1.9e-06 27.9 0.0 2.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFO95016.1 - 0.00023 21.3 0.0 0.00034 20.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 KFO95016.1 - 0.0019 18.2 0.0 0.0026 17.8 0.0 1.1 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFO95016.1 - 0.054 13.9 0.0 0.079 13.4 0.0 1.2 1 0 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ribosomal_L13 PF00572.18 KFO95017.1 - 3e-07 30.7 0.1 4e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 GCV_H PF01597.19 KFO95018.1 - 3.1e-08 33.5 0.0 3.4e-08 33.4 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein TMEM132D_N PF15705.5 KFO95020.1 - 1.2e-38 131.9 0.6 1.4e-38 131.7 0.6 1.0 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term p450 PF00067.22 KFO95021.1 - 5.5e-41 140.8 0.0 6.3e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L30_N PF08079.12 KFO95022.1 - 4.1e-28 97.4 17.6 4.9e-28 97.2 17.6 1.1 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain SNAD2 PF18745.1 KFO95022.1 - 0.2 11.3 1.3 0.23 11.1 1.3 1.1 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 2 DUF4798 PF16055.5 KFO95022.1 - 1.2 9.4 9.2 1.6 9.0 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4798) V-set PF07686.17 KFO95024.1 - 3.6e-12 46.4 0.1 4.5e-12 46.1 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain V-set_2 PF15910.5 KFO95024.1 - 3.6e-12 46.4 0.1 4.5e-12 46.1 0.1 1.1 1 0 0 1 1 1 1 ICOS V-set domain Ig_3 PF13927.6 KFO95024.1 - 0.0084 16.7 0.0 0.016 15.8 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 KFO95024.1 - 0.069 12.7 0.1 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 Immunoglobulin domain I-set PF07679.16 KFO95024.1 - 0.078 13.1 0.0 0.12 12.5 0.0 1.4 1 1 0 1 1 1 0 Immunoglobulin I-set domain PHD PF00628.29 KFO95025.1 - 4.9e-06 26.3 5.8 4.9e-06 26.3 5.8 1.5 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KFO95025.1 - 0.00012 21.5 5.0 0.00039 19.9 1.7 2.3 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.22 KFO95025.1 - 0.0023 17.8 1.0 0.0023 17.8 1.0 1.9 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RRPl_C4 PF17026.5 KFO95025.1 - 0.022 14.8 1.3 0.022 14.8 1.3 1.7 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type C1_2 PF03107.16 KFO95025.1 - 0.16 12.3 5.9 0.2 12.0 5.9 1.3 1 1 0 1 1 1 0 C1 domain Prok-RING_1 PF14446.6 KFO95025.1 - 0.66 9.9 12.7 0.35 10.8 8.1 2.2 1 1 0 2 2 2 0 Prokaryotic RING finger family 1 JmjC PF02373.22 KFO95026.1 - 1e-14 54.9 0.0 1.5e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KFO95026.1 - 0.017 14.8 0.0 0.017 14.8 0.0 2.2 2 1 0 2 2 2 0 Cupin domain CLASP_N PF12348.8 KFO95027.1 - 3.8e-06 26.7 0.1 3.8e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.22 KFO95027.1 - 0.0027 17.8 0.5 3 8.3 0.1 3.1 3 0 0 3 3 3 2 HEAT repeat ABC2_membrane PF01061.24 KFO95028.1 - 2.3e-20 72.9 9.7 2.3e-20 72.9 9.7 1.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KFO95028.1 - 0.00073 18.7 6.7 0.00091 18.4 6.7 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 KFO95028.1 - 0.092 12.0 4.5 0.12 11.6 4.5 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein TSP_C PF05735.12 KFO95029.1 - 1.3e-56 191.6 2.6 1.5e-56 191.5 2.6 1.0 1 0 0 1 1 1 1 Thrombospondin C-terminal region EGF PF00008.27 KFO95030.1 - 0.02 15.2 3.4 0.049 13.9 3.4 1.8 1 0 0 1 1 1 0 EGF-like domain DUF4514 PF14986.6 KFO95030.1 - 0.069 13.1 0.5 0.13 12.2 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) SKG6 PF08693.10 KFO95030.1 - 0.59 9.6 5.5 1.3 8.5 5.5 1.5 1 1 0 1 1 1 0 Transmembrane alpha-helix domain RhoGEF PF00621.20 KFO95031.1 - 8.1e-15 55.5 0.3 8.9e-15 55.4 0.3 1.0 1 0 0 1 1 1 1 RhoGEF domain PMP22_Claudin PF00822.20 KFO95032.1 - 1.8e-13 50.7 3.2 2e-13 50.6 3.2 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFO95032.1 - 7.3e-06 25.9 5.9 7.6e-06 25.8 5.9 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.11 KFO95032.1 - 0.031 14.1 3.4 0.034 14.0 3.4 1.1 1 0 0 1 1 1 0 Amastin surface glycoprotein Phage_holin_3_6 PF07332.11 KFO95032.1 - 0.043 13.8 5.0 0.053 13.6 5.0 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Trypsin PF00089.26 KFO95033.1 - 3.9e-19 69.4 0.5 4.2e-19 69.2 0.5 1.0 1 0 0 1 1 1 1 Trypsin LSM14 PF12701.7 KFO95034.1 - 0.13 12.4 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Scd6-like Sm domain Fumble PF03630.14 KFO95035.1 - 7.5e-39 133.8 0.0 8.1e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 Fumble TIR PF01582.20 KFO95036.1 - 2.1e-08 34.2 0.0 2.6e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 TIR domain Lipocalin_7 PF14651.6 KFO95038.1 - 1.3e-25 89.8 0.8 1.4e-25 89.7 0.8 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.23 KFO95038.1 - 5e-10 39.7 0.8 5.4e-10 39.6 0.8 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Trypsin PF00089.26 KFO95039.1 - 7.3e-18 65.2 0.0 8.2e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFO95039.1 - 0.002 18.5 0.0 0.0023 18.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF5583 PF17821.1 KFO95039.1 - 0.041 13.8 0.0 0.062 13.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5583) RRM_1 PF00076.22 KFO95040.1 - 5.4e-23 80.6 0.1 2.2e-20 72.2 0.1 2.7 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFO95040.1 - 0.18 11.9 0.2 1.8 8.8 0.1 2.5 1 1 1 2 2 2 0 RNA recognition motif Pkinase_Tyr PF07714.17 KFO95041.1 - 7.9e-08 31.9 0.0 8.3e-08 31.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO95041.1 - 7.5e-07 28.8 0.0 8.6e-07 28.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.12 KFO95041.1 - 4.9e-06 25.9 1.0 7.6e-06 25.3 1.0 1.3 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif FTA2 PF13095.6 KFO95041.1 - 0.0048 16.5 0.0 0.0051 16.5 0.0 1.0 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Herpes_US9 PF06072.11 KFO95042.1 - 0.084 12.8 0.4 0.13 12.2 0.4 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 KH_1 PF00013.29 KFO95044.1 - 4.1e-12 45.8 0.0 5.6e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 KFO95044.1 - 0.0043 16.9 0.0 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 KH domain DUF4566 PF15130.6 KFO95045.1 - 9.8e-89 296.6 0.4 1.1e-88 296.5 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4566) Coilin_N PF15862.5 KFO95046.1 - 0.068 13.0 10.0 0.073 12.9 10.0 1.0 1 0 0 1 1 1 0 Coilin N-terminus SR-25 PF10500.9 KFO95046.1 - 0.11 12.1 14.2 0.12 11.9 14.2 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cytomega_UL84 PF06284.11 KFO95046.1 - 0.65 8.4 5.0 0.63 8.4 5.0 1.0 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein CDC45 PF02724.14 KFO95046.1 - 2.3 6.4 9.1 2.2 6.5 9.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S49_N PF08496.10 KFO95046.1 - 2.7 8.0 8.5 2.8 8.0 8.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal MAP17 PF15807.5 KFO95046.1 - 2.8 8.2 8.1 3.1 8.1 8.1 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF3915 PF13054.6 KFO95046.1 - 6.3 6.8 7.9 7.6 6.5 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF1682 PF07946.14 KFO95046.1 - 9.2 5.4 15.7 11 5.1 15.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF2373 PF10180.9 KFO95048.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.5 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Tfb5 PF06331.12 KFO95049.1 - 2e-20 72.5 0.1 2.2e-20 72.4 0.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Metallophos PF00149.28 KFO95051.1 - 1.8e-22 80.9 0.1 2e-22 80.7 0.1 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 KFO95051.1 - 0.016 14.5 0.0 0.02 14.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Laminin_EGF PF00053.24 KFO95052.1 - 2.1e-12 47.0 23.5 9.9e-08 32.0 16.4 2.1 2 0 0 2 2 2 2 Laminin EGF domain Mesothelin PF06060.12 KFO95053.1 - 8.6e-39 133.2 0.0 9.3e-39 133.1 0.0 1.0 1 0 0 1 1 1 1 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) Flavodoxin_NdrI PF07972.11 KFO95053.1 - 0.23 11.6 0.0 0.32 11.2 0.0 1.2 1 0 0 1 1 1 0 NrdI Flavodoxin like Yippee-Mis18 PF03226.14 KFO95054.1 - 1.7e-09 37.9 0.0 1.7e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RRM_occluded PF16842.5 KFO95056.1 - 0.0013 18.5 0.2 0.32 10.9 0.1 2.4 1 1 1 2 2 2 2 Occluded RNA-recognition motif Collagen_bind PF05737.12 KFO95056.1 - 0.017 15.3 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 Collagen binding domain Ferric_reduct PF01794.19 KFO95058.1 - 4.1e-13 49.5 2.8 4.1e-13 49.5 2.8 1.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NigD_C PF17415.2 KFO95058.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 NigD-like C-terminal beta sandwich domain Enolase_C PF00113.22 KFO95059.1 - 7.9e-79 265.0 0.0 8.7e-79 264.8 0.0 1.0 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain MR_MLE_C PF13378.6 KFO95059.1 - 6.1e-09 35.8 0.0 6.5e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KFO95059.1 - 0.0001 21.5 0.4 0.00013 21.3 0.4 1.2 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus HSP70 PF00012.20 KFO95060.1 - 4.3e-11 41.7 0.2 4.3e-06 25.2 0.0 2.0 1 1 1 2 2 2 2 Hsp70 protein Mltc_N PF11873.8 KFO95060.1 - 0.07 12.8 0.1 0.14 11.9 0.1 1.5 1 1 0 1 1 1 0 Membrane-bound lytic murein transglycosylase C, N-terminal domain Patched PF02460.18 KFO95061.1 - 4.8e-72 243.3 14.7 6.5e-72 242.8 14.7 1.2 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 KFO95061.1 - 2.1e-12 47.1 0.9 2.1e-12 47.1 0.9 2.7 3 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation Phage_holin_3_6 PF07332.11 KFO95061.1 - 0.15 12.1 1.9 28 4.8 0.0 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Tubulin PF00091.25 KFO95062.1 - 8.9e-58 195.7 0.0 1.1e-57 195.5 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 KFO95062.1 - 0.0014 17.9 0.0 0.0024 17.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin like ANF_receptor PF01094.28 KFO95063.1 - 0.0039 16.4 0.0 0.0039 16.3 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region TRAP-gamma PF07074.12 KFO95064.1 - 1.7e-64 216.4 6.1 1.9e-64 216.3 6.1 1.0 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) Renin_r PF07850.14 KFO95064.1 - 0.014 16.0 1.1 0.021 15.4 0.3 1.7 1 1 0 2 2 2 0 Renin receptor-like protein SPC25 PF06703.11 KFO95064.1 - 0.11 12.3 3.8 0.063 13.1 1.6 1.7 1 1 1 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Ins145_P3_rec PF08709.11 KFO95066.1 - 1.4e-05 24.4 0.1 1.4e-05 24.4 0.1 1.0 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor I-set PF07679.16 KFO95067.1 - 7.6e-07 29.1 0.0 1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO95067.1 - 0.033 14.8 0.0 0.053 14.1 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain Peptidase_M10 PF00413.24 KFO95068.1 - 1.8e-60 203.4 0.0 2.2e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.18 KFO95068.1 - 1.1e-08 35.2 0.1 3.2e-08 33.7 0.1 1.9 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Reprolysin_3 PF13582.6 KFO95068.1 - 2e-05 25.1 0.0 3.9e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 KFO95068.1 - 9.4e-05 22.1 0.7 0.23 11.0 0.1 2.1 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.6 KFO95068.1 - 0.0002 21.6 0.0 0.00026 21.2 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KFO95068.1 - 0.0014 18.3 0.1 0.0019 17.9 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 KFO95068.1 - 0.006 16.6 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M54 DUF4953 PF16313.5 KFO95068.1 - 0.026 13.7 0.2 0.054 12.7 0.2 1.5 2 0 0 2 2 2 0 Met-zincin Peptidase_M66 PF10462.9 KFO95068.1 - 0.04 12.9 0.2 0.063 12.2 0.2 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M57 PF12388.8 KFO95068.1 - 0.081 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Metallopep PF12044.8 KFO95068.1 - 0.087 11.4 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_2 PF13574.6 KFO95068.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like ALIX_LYPXL_bnd PF13949.6 KFO95070.1 - 8.5e-31 107.3 11.6 9.9e-31 107.1 11.6 1.0 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Rho_Binding PF08912.11 KFO95070.1 - 0.0037 18.1 10.0 0.064 14.1 5.5 2.2 2 0 0 2 2 2 1 Rho Binding GAS PF13851.6 KFO95070.1 - 0.009 15.4 9.3 0.066 12.6 5.3 2.0 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Snapin_Pallidin PF14712.6 KFO95070.1 - 0.011 16.2 7.9 0.021 15.2 2.9 2.2 2 0 0 2 2 2 0 Snapin/Pallidin Methyltransf_7 PF03492.15 KFO95070.1 - 0.011 14.9 2.2 0.013 14.8 2.2 1.0 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase JIP_LZII PF16471.5 KFO95070.1 - 0.016 15.3 0.4 0.016 15.3 0.4 2.5 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II Med10 PF09748.9 KFO95070.1 - 0.029 14.3 1.8 0.041 13.8 1.8 1.2 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex T2SSM PF04612.12 KFO95070.1 - 0.033 14.2 3.4 4.4 7.4 1.3 2.1 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M DUF5564 PF17719.1 KFO95070.1 - 0.035 14.2 1.0 0.068 13.3 0.3 1.7 1 1 0 2 2 2 0 Family of unknown function (DUF5564) PI_PP_I PF18363.1 KFO95070.1 - 0.059 13.6 2.3 5 7.4 0.1 2.2 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain Wtap PF17098.5 KFO95070.1 - 0.06 13.3 11.1 0.38 10.7 11.1 2.2 1 1 0 1 1 1 0 WTAP/Mum2p family RNA_pol_Rpb2_6 PF00562.28 KFO95070.1 - 0.087 11.9 1.8 0.088 11.9 1.8 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 Syntaxin-6_N PF09177.11 KFO95070.1 - 0.16 12.6 4.5 0.68 10.5 1.5 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Fe_hyd_lg_C PF02906.14 KFO95070.1 - 0.2 11.3 2.1 0.25 11.0 2.1 1.0 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain DUF948 PF06103.11 KFO95070.1 - 0.28 11.5 3.2 2.4 8.5 2.3 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF4355 PF14265.6 KFO95070.1 - 0.42 10.9 13.0 0.054 13.7 7.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4355) Nup88 PF10168.9 KFO95070.1 - 0.46 8.2 7.6 0.51 8.1 7.6 1.0 1 0 0 1 1 1 0 Nuclear pore component Ly49 PF08391.10 KFO95070.1 - 0.51 10.7 8.6 0.23 11.8 5.2 1.9 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region DUF1978 PF09321.10 KFO95070.1 - 0.52 9.6 10.7 0.13 11.5 5.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1978) YebO PF13974.6 KFO95070.1 - 0.62 10.2 7.7 0.3 11.2 3.3 2.2 2 0 0 2 2 2 0 YebO-like protein DUF2408 PF10303.9 KFO95070.1 - 1.2 9.7 9.2 2.2 8.8 9.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) HIP1_clath_bdg PF16515.5 KFO95070.1 - 1.2 9.7 10.8 4.6 7.9 5.2 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 XhlA PF10779.9 KFO95070.1 - 2.1 8.6 8.1 1.8 8.8 0.7 2.6 3 0 0 3 3 3 0 Haemolysin XhlA APG6_N PF17675.1 KFO95070.1 - 5.2 7.6 13.2 19 5.8 13.3 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region TSP_C PF05735.12 KFO95071.1 - 5.3e-84 281.1 0.9 5.9e-84 280.9 0.9 1.0 1 0 0 1 1 1 1 Thrombospondin C-terminal region Globin PF00042.22 KFO95073.1 - 5.4e-21 75.2 0.0 7.8e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Globin Trypsin PF00089.26 KFO95074.1 - 4.6e-11 42.9 0.0 4e-09 36.6 0.0 2.5 3 0 0 3 3 3 1 Trypsin Trypsin_2 PF13365.6 KFO95074.1 - 6.1e-06 27.2 0.0 1.3e-05 26.1 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 KFO95074.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 LAP1C PF05609.12 KFO95074.1 - 0.16 11.0 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Med21 PF11221.8 KFO95077.1 - 0.22 11.8 7.3 0.076 13.3 4.1 1.7 1 1 1 2 2 2 0 Subunit 21 of Mediator complex RNA_pol_A_bac PF01000.26 KFO95078.1 - 4.5e-30 104.3 0.0 6.9e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KFO95078.1 - 0.00071 19.0 0.0 0.00091 18.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain FAST_1 PF06743.15 KFO95079.1 - 9.7e-21 73.5 2.4 9.7e-21 73.5 2.4 4.0 3 1 0 4 4 4 1 FAST kinase-like protein, subdomain 1 CARMIL_C PF16000.5 KFO95079.1 - 0.12 12.0 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 CARMIL C-terminus HALZ PF02183.18 KFO95080.1 - 0.00049 20.3 0.6 0.00077 19.6 0.5 1.5 1 1 0 1 1 1 1 Homeobox associated leucine zipper SYCE1 PF15233.6 KFO95080.1 - 0.0016 18.5 0.2 0.0017 18.5 0.2 1.1 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 bZIP_1 PF00170.21 KFO95080.1 - 0.0042 17.2 1.6 0.0049 16.9 1.6 1.2 1 0 0 1 1 1 1 bZIP transcription factor GAS PF13851.6 KFO95080.1 - 0.0097 15.3 0.3 0.01 15.2 0.3 1.0 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Cnn_1N PF07989.11 KFO95080.1 - 0.01 16.0 1.9 0.012 15.7 1.9 1.1 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 TPD52 PF04201.15 KFO95080.1 - 0.011 15.3 0.3 0.012 15.2 0.3 1.0 1 0 0 1 1 1 0 Tumour protein D52 family Cep57_CLD_2 PF14197.6 KFO95080.1 - 0.02 14.9 0.6 0.024 14.7 0.6 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Rootletin PF15035.6 KFO95080.1 - 0.029 14.4 0.3 0.032 14.2 0.3 1.0 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion ZapB PF06005.12 KFO95080.1 - 0.039 14.4 0.9 0.046 14.2 0.9 1.1 1 0 0 1 1 1 0 Cell division protein ZapB DivIVA PF05103.13 KFO95080.1 - 0.044 13.9 1.2 0.049 13.7 1.2 1.1 1 0 0 1 1 1 0 DivIVA protein DivIC PF04977.15 KFO95080.1 - 0.052 13.3 0.7 0.061 13.1 0.7 1.2 1 0 0 1 1 1 0 Septum formation initiator PI3K_P85_iSH2 PF16454.5 KFO95080.1 - 0.057 13.0 0.4 0.059 13.0 0.4 1.0 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Rx_N PF18052.1 KFO95080.1 - 0.072 13.4 0.2 0.078 13.3 0.2 1.1 1 0 0 1 1 1 0 Rx N-terminal domain DUF1640 PF07798.11 KFO95080.1 - 0.1 12.7 0.7 0.11 12.5 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) TMF_DNA_bd PF12329.8 KFO95080.1 - 0.11 12.5 2.9 0.13 12.3 2.9 1.0 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF1818 PF08848.11 KFO95080.1 - 0.12 12.5 0.2 0.12 12.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1818) NYD-SP28_assoc PF14775.6 KFO95080.1 - 0.18 11.9 0.9 2.7 8.2 0.3 2.0 1 1 1 2 2 2 0 Sperm tail C-terminal domain APC_N_CC PF16689.5 KFO95080.1 - 0.31 11.1 2.6 0.51 10.5 2.6 1.4 1 1 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain Ifi-6-16 PF06140.13 KFO95081.1 - 2e-11 43.6 10.1 2.3e-11 43.4 10.1 1.1 1 0 0 1 1 1 1 Interferon-induced 6-16 family NAD_binding_11 PF14833.6 KFO95082.1 - 8.3e-08 32.5 1.1 8.3e-08 32.5 1.1 1.5 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 KFO95082.1 - 1.7e-07 31.5 0.2 2.7e-07 30.9 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase PHF5 PF03660.14 KFO95083.1 - 2.3e-22 79.2 10.8 2.5e-22 79.1 10.8 1.0 1 0 0 1 1 1 1 PHF5-like protein C1_2 PF03107.16 KFO95083.1 - 0.049 14.0 2.9 0.049 14.0 2.9 2.3 1 1 1 2 2 2 0 C1 domain PolC_DP2 PF03833.13 KFO95083.1 - 0.32 8.8 6.2 0.31 8.8 6.2 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 KFO95083.1 - 0.42 10.7 10.8 5.4 7.1 10.9 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-RanBP PF00641.18 KFO95083.1 - 2.1 7.7 9.8 10 5.5 0.0 3.8 4 0 0 4 4 4 0 Zn-finger in Ran binding protein and others PDZ PF00595.24 KFO95084.1 - 3.5e-20 72.1 0.2 4.4e-20 71.8 0.2 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFO95084.1 - 1.8e-11 44.2 0.3 2.5e-11 43.7 0.3 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFO95084.1 - 3.9e-11 42.6 0.1 7.2e-11 41.8 0.1 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KFO95084.1 - 0.13 12.6 0.1 0.23 11.8 0.0 1.4 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain Mustang PF15682.5 KFO95085.1 - 1e-40 137.7 3.4 1.1e-40 137.6 3.4 1.0 1 0 0 1 1 1 1 Musculoskeletal, temporally activated-embryonic nuclear protein 1 Ras PF00071.22 KFO95086.1 - 1.3e-29 102.9 0.0 1.6e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO95086.1 - 7.5e-06 26.2 0.0 1.4e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase CENP-M PF11111.8 KFO95086.1 - 0.082 12.1 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Centromere protein M (CENP-M) 7tm_1 PF00001.21 KFO95087.1 - 4.9e-07 29.4 11.7 2.1e-06 27.3 11.7 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srbc PF10316.9 KFO95087.1 - 0.00032 20.3 0.8 0.00032 20.3 0.8 2.4 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc RseC_MucC PF04246.12 KFO95087.1 - 5.6 6.9 5.5 2.6 8.0 2.0 2.0 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC TPR_1 PF00515.28 KFO95088.1 - 6.6e-20 70.0 4.2 4.6e-07 29.4 3.8 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFO95088.1 - 4.7e-17 60.7 4.3 9.5e-07 28.5 1.6 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFO95088.1 - 5.9e-11 41.9 4.1 1.5e-07 30.9 5.0 3.0 1 1 2 3 3 3 2 TPR repeat TPR_8 PF13181.6 KFO95088.1 - 4.3e-09 35.9 1.9 0.00074 19.5 1.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFO95088.1 - 1.1e-08 34.8 3.2 6.9e-06 26.1 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFO95088.1 - 2.8e-08 33.9 4.2 1.6e-06 28.3 1.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFO95088.1 - 7.9e-08 32.5 0.2 0.014 16.2 0.0 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFO95088.1 - 1.5e-06 28.4 2.7 0.079 13.6 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFO95088.1 - 1.9e-06 28.3 0.5 0.0063 17.0 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFO95088.1 - 1.4e-05 25.7 0.6 0.0019 18.8 0.5 2.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFO95088.1 - 8.7e-05 22.3 4.5 0.11 12.4 0.4 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFO95088.1 - 0.00039 20.5 0.2 0.14 12.3 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFO95088.1 - 0.00056 19.8 1.5 1.4 9.1 0.1 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO95088.1 - 0.0049 17.1 5.5 0.049 13.9 1.7 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 KFO95088.1 - 0.0065 16.4 3.4 0.061 13.3 3.8 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFO95088.1 - 0.045 12.9 1.9 2.5 7.2 0.0 2.4 1 1 0 2 2 2 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KFO95088.1 - 0.09 13.2 1.3 9.8 6.6 0.1 2.1 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation Fis1_TPR_C PF14853.6 KFO95088.1 - 0.2 11.8 4.8 2.1 8.5 0.1 2.4 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 KFO95088.1 - 0.24 11.5 4.9 0.23 11.6 2.2 2.2 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain ADH_zinc_N PF00107.26 KFO95090.1 - 5.6e-22 78.1 0.3 7.1e-22 77.8 0.3 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFO95090.1 - 9.9e-19 68.7 0.0 1.2e-18 68.5 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase I-set PF07679.16 KFO95091.1 - 4.7e-12 45.8 0.0 6.3e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO95091.1 - 6.1e-07 29.9 0.0 9.5e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFO95091.1 - 3.5e-05 23.9 0.0 4.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 KFO95091.1 - 0.00027 20.5 0.0 0.00045 19.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFO95091.1 - 0.00035 20.8 0.0 0.00058 20.1 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFO95091.1 - 0.0018 18.3 0.0 0.0036 17.3 0.0 1.4 1 0 0 1 1 1 1 Izumo-like Immunoglobulin domain V-set PF07686.17 KFO95091.1 - 0.0025 18.0 0.0 0.0034 17.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain Pkinase_Tyr PF07714.17 KFO95092.1 - 4.8e-14 52.3 0.0 5.8e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO95092.1 - 7e-13 48.5 0.0 7.7e-13 48.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KFO95092.1 - 0.0023 17.9 0.1 0.0027 17.7 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFO95092.1 - 0.013 14.5 0.1 0.016 14.2 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KFO95092.1 - 0.15 11.7 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 RIO1 family 7tm_1 PF00001.21 KFO95093.1 - 1.2e-16 60.8 15.8 1.2e-16 60.8 15.8 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFO95093.1 - 0.00017 21.3 20.0 0.00025 20.8 20.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.15 KFO95093.1 - 0.0004 20.4 4.3 0.0004 20.4 4.3 2.7 1 1 1 3 3 3 2 Caenorhabditis serpentine receptor-like protein, class xa 7TM_GPCR_Srv PF10323.9 KFO95093.1 - 0.015 14.7 13.8 0.023 14.1 13.3 1.5 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv NPCC PF08058.11 KFO95093.1 - 3.3 7.8 8.3 35 4.4 5.4 2.9 2 1 0 2 2 2 0 Nuclear pore complex component DUF3561 PF12084.8 KFO95093.1 - 7.9 6.6 13.2 0.96 9.5 5.7 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3561) ARA70 PF12489.8 KFO95097.1 - 2.4e-41 141.1 24.2 1e-38 132.6 7.8 4.6 1 1 3 4 4 4 2 Nuclear coactivator BRK PF07533.16 KFO95097.1 - 0.093 12.4 10.8 0.33 10.6 0.1 4.1 4 0 0 4 4 4 0 BRK domain CTP_transf_like PF01467.26 KFO95098.1 - 5.9e-10 39.5 0.0 7.8e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like ChapFlgA PF13144.6 KFO95098.1 - 0.038 14.0 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 Chaperone for flagella basal body P-ring formation DUF4258 PF14076.6 KFO95098.1 - 0.064 13.6 0.2 0.16 12.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4258) RNA_bind PF08675.11 KFO95098.1 - 0.15 12.1 0.0 0.57 10.3 0.0 1.8 1 1 0 2 2 2 0 RNA binding domain HAP1_N PF04849.13 KFO95099.1 - 0.00031 20.1 37.8 0.00044 19.5 11.6 2.1 1 1 1 2 2 2 2 HAP1 N-terminal conserved region UFD1 PF03152.14 KFO95099.1 - 0.018 14.5 5.1 0.2 11.1 0.3 2.2 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 Ax_dynein_light PF10211.9 KFO95099.1 - 0.44 10.5 31.6 0.14 12.1 13.9 3.0 1 1 1 2 2 2 0 Axonemal dynein light chain HHA PF05321.11 KFO95099.1 - 0.88 9.9 4.5 2.9 8.3 1.0 2.9 2 1 0 2 2 2 0 Haemolysin expression modulating protein Retrotrans_gag PF03732.17 KFO95099.1 - 2.8 8.3 16.0 8.5 6.7 1.7 3.9 2 1 1 3 3 3 0 Retrotransposon gag protein TMF_TATA_bd PF12325.8 KFO95099.1 - 4.1 7.6 32.8 8.4 6.6 11.1 3.1 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding YabA PF06156.13 KFO95099.1 - 4.9 7.9 30.2 1.1 9.9 14.3 3.7 1 1 3 4 4 4 0 Initiation control protein YabA GAS PF13851.6 KFO95099.1 - 6.3 6.1 39.5 1.8 7.9 18.9 2.6 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Cnn_1N PF07989.11 KFO95099.1 - 6.4 7.0 32.2 1.8 8.8 17.4 3.2 2 2 1 3 3 3 0 Centrosomin N-terminal motif 1 DUF1664 PF07889.12 KFO95099.1 - 7.1 6.7 18.8 4 7.5 3.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 KFO95099.1 - 7.2 6.8 37.9 2.5 8.3 19.4 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 KFO95099.1 - 8.6 6.9 39.1 8.4 6.9 11.8 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region MTCP1 PF08991.10 KFO95100.1 - 3.4e-10 40.0 6.1 3.6e-10 39.9 6.1 1.0 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type AhpC-TSA PF00578.21 KFO95101.1 - 7.5e-22 77.6 0.0 9.1e-22 77.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFO95101.1 - 3.7e-06 26.7 0.0 4.7e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin Yip1 PF04893.17 KFO95102.1 - 2.6e-06 27.3 20.2 4.2e-06 26.6 20.2 1.4 1 1 0 1 1 1 1 Yip1 domain Romo1 PF10247.9 KFO95102.1 - 0.032 14.6 2.2 0.032 14.6 2.2 2.1 2 1 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 YIF1 PF03878.15 KFO95102.1 - 0.29 10.6 10.4 0.4 10.2 10.4 1.2 1 1 0 1 1 1 0 YIF1 Prokineticin PF06607.11 KFO95103.1 - 0.0023 18.2 7.2 0.0028 17.9 7.2 1.1 1 0 0 1 1 1 1 Prokineticin Dickkopf_N PF04706.12 KFO95103.1 - 0.027 14.9 5.9 0.027 14.9 5.9 2.1 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Toxin_21 PF08091.11 KFO95103.1 - 3 7.9 12.4 0.075 13.0 4.7 2.2 2 1 0 2 2 2 0 Spider insecticidal peptide Tub_N PF16322.5 KFO95106.1 - 2.8e-23 83.4 5.4 3e-23 83.3 5.4 1.0 1 0 0 1 1 1 1 Tubby N-terminal JAMP PF05571.12 KFO95107.1 - 1e-84 284.7 12.6 1.1e-84 284.5 12.6 1.0 1 0 0 1 1 1 1 JNK1/MAPK8-associated membrane protein DHC_N1 PF08385.12 KFO95108.1 - 6e-35 120.9 2.2 6.5e-35 120.8 2.2 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 DCX PF03607.17 KFO95108.1 - 0.039 14.0 0.1 3.2 7.9 0.1 2.5 1 1 0 1 1 1 0 Doublecortin G-gamma PF00631.22 KFO95109.1 - 1.6e-10 40.9 0.0 1.7e-10 40.8 0.0 1.0 1 0 0 1 1 1 1 GGL domain EF-hand_1 PF00036.32 KFO95110.1 - 5.9e-13 47.4 2.7 0.00018 20.8 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 KFO95110.1 - 5.6e-09 36.3 6.1 0.00085 19.7 0.2 3.2 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 KFO95110.1 - 7.1e-07 28.7 0.2 0.15 12.1 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 KFO95110.1 - 3.1e-05 23.3 3.4 0.00063 19.1 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 KFO95110.1 - 0.007 16.2 3.4 0.85 9.5 0.1 3.4 3 1 1 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFO95110.1 - 0.015 15.6 4.2 0.27 11.6 1.5 2.3 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region PDEase_I PF00233.19 KFO95111.1 - 9.5e-36 123.7 0.2 1e-35 123.6 0.2 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DHHC PF01529.20 KFO95112.1 - 6.9e-29 100.6 10.3 9.9e-29 100.1 10.3 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Baculo_11_kDa PF06143.11 KFO95112.1 - 0.097 12.3 1.2 0.14 11.7 1.2 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family C2 PF00168.30 KFO95113.1 - 1.3e-20 73.6 0.1 1.8e-20 73.1 0.1 1.2 1 0 0 1 1 1 1 C2 domain Myosin_head PF00063.21 KFO95114.1 - 8.1e-52 176.4 0.0 1.2e-51 175.8 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 KFO95114.1 - 7.9e-06 25.2 0.7 1.9e-05 24.1 0.1 2.0 2 0 0 2 2 2 1 IQ calmodulin-binding motif Intron_maturas2 PF01348.21 KFO95114.1 - 0.095 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Type II intron maturase YdjC PF04794.12 KFO95115.1 - 7e-22 78.6 0.0 7.3e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 YdjC-like protein Propep_M14 PF02244.16 KFO95115.1 - 0.16 12.4 0.1 0.28 11.6 0.1 1.4 1 0 0 1 1 1 0 Carboxypeptidase activation peptide 14-3-3 PF00244.20 KFO95116.1 - 3.3e-44 151.0 0.4 3.6e-44 150.9 0.4 1.0 1 0 0 1 1 1 1 14-3-3 protein Ank_3 PF13606.6 KFO95117.1 - 2e-05 24.6 0.5 0.002 18.5 0.2 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 KFO95117.1 - 2.4e-05 24.9 1.0 0.0088 16.6 0.1 2.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFO95117.1 - 0.0041 17.7 0.9 0.35 11.5 0.2 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KFO95117.1 - 0.056 13.9 0.1 0.19 12.3 0.1 1.9 1 0 0 1 1 1 0 Ankyrin repeat HECT PF00632.25 KFO95118.1 - 7.1e-22 78.3 0.0 8.3e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Metallophos PF00149.28 KFO95119.1 - 7.2e-08 33.2 0.0 9.2e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ABC_tran PF00005.27 KFO95120.1 - 5.3e-09 36.7 0.0 6.2e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFO95120.1 - 7.1e-06 26.0 0.0 8.2e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFO95120.1 - 0.00012 22.7 0.1 0.00013 22.5 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KFO95120.1 - 0.00031 20.4 0.0 0.00047 19.8 0.0 1.2 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.15 KFO95120.1 - 0.00086 19.3 0.0 0.001 19.0 0.0 1.1 1 0 0 1 1 1 1 Rad17 P-loop domain Adeno_IVa2 PF02456.15 KFO95120.1 - 0.00092 18.1 0.0 0.00093 18.1 0.0 1.0 1 0 0 1 1 1 1 Adenovirus IVa2 protein SMC_N PF02463.19 KFO95120.1 - 0.0076 15.7 0.1 0.0095 15.4 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFO95120.1 - 0.013 15.9 0.1 0.016 15.6 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.21 KFO95120.1 - 0.023 14.1 0.0 0.027 13.9 0.0 1.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Lon_2 PF13337.6 KFO95120.1 - 0.027 13.0 0.0 0.031 12.8 0.0 1.0 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease DUF815 PF05673.13 KFO95120.1 - 0.047 12.9 0.0 0.057 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_27 PF13514.6 KFO95120.1 - 0.047 13.3 0.0 0.057 13.0 0.0 1.0 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KFO95120.1 - 0.059 13.4 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 KFO95120.1 - 0.063 13.2 0.0 0.067 13.1 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KFO95120.1 - 0.072 12.6 0.0 0.084 12.4 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KFO95120.1 - 0.1 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 KFO95120.1 - 0.13 12.6 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KFO95120.1 - 0.13 12.6 0.0 0.17 12.3 0.0 1.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KFO95120.1 - 0.14 12.0 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase T2SSE PF00437.20 KFO95120.1 - 0.15 11.1 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_15 PF13175.6 KFO95120.1 - 0.15 11.8 0.1 0.17 11.6 0.1 1.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KFO95120.1 - 0.15 12.6 0.0 0.19 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2813 PF11398.8 KFO95120.1 - 0.21 10.8 0.0 0.22 10.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) RNA_helicase PF00910.22 KFO95120.1 - 0.23 11.9 0.0 0.26 11.7 0.0 1.2 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 KFO95120.1 - 0.24 11.6 0.0 0.29 11.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KFO95120.1 - 0.26 11.0 0.0 0.29 10.8 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 KFO95120.1 - 0.29 10.8 0.0 0.37 10.5 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF1958 PF09211.10 KFO95121.1 - 0.09 13.1 0.0 0.78 10.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1958) Glyco_transf_29 PF00777.18 KFO95121.1 - 0.093 12.1 0.3 0.27 10.6 0.0 1.8 2 1 0 2 2 2 0 Glycosyltransferase family 29 (sialyltransferase) GTP_EFTU PF00009.27 KFO95122.1 - 1.5e-54 184.5 0.0 2e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFO95122.1 - 2.3e-28 98.7 0.0 5.2e-28 97.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KFO95122.1 - 3.8e-15 56.0 1.8 5.5e-15 55.5 0.6 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFO95122.1 - 0.00025 21.1 0.1 0.0068 16.5 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KFO95122.1 - 0.013 15.4 0.8 0.028 14.3 0.2 1.9 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Dynamin_N PF00350.23 KFO95122.1 - 0.064 13.3 0.1 15 5.6 0.1 2.4 2 0 0 2 2 2 0 Dynamin family G-alpha PF00503.20 KFO95122.1 - 0.2 10.8 0.2 0.64 9.1 0.1 1.8 1 1 0 2 2 2 0 G-protein alpha subunit PP1_bind PF15276.6 KFO95123.1 - 1.3e-22 79.8 0.5 2e-22 79.2 0.5 1.3 1 0 0 1 1 1 1 Protein phosphatase 1 binding SRCR PF00530.18 KFO95125.1 - 1.3e-57 192.4 16.6 6.7e-34 116.4 7.0 2.0 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFO95125.1 - 1.6e-06 28.5 2.6 0.00058 20.4 0.4 2.4 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain bZIP_1 PF00170.21 KFO95126.1 - 7.8e-12 45.1 18.2 1.4e-11 44.3 18.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFO95126.1 - 1.1e-09 38.2 19.2 1.7e-09 37.6 19.2 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFO95126.1 - 9.3e-08 32.5 7.9 9.3e-08 32.5 7.9 1.6 2 0 0 2 2 2 1 bZIP Maf transcription factor Dapper PF15268.6 KFO95126.1 - 0.0057 15.6 2.0 0.0059 15.5 2.0 1.0 1 0 0 1 1 1 1 Dapper APG6_N PF17675.1 KFO95126.1 - 0.0065 17.0 8.7 0.01 16.4 8.7 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region FemAB PF02388.16 KFO95126.1 - 0.018 14.0 1.4 0.022 13.7 1.4 1.1 1 0 0 1 1 1 0 FemAB family Ribosomal_L6e PF01159.19 KFO95126.1 - 0.058 13.9 6.7 0.13 12.8 6.5 1.6 1 1 1 2 2 2 0 Ribosomal protein L6e Afi1 PF07792.12 KFO95126.1 - 0.074 13.5 2.8 0.11 13.0 2.8 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DivIC PF04977.15 KFO95126.1 - 0.3 10.9 7.5 0.41 10.4 6.7 1.7 2 0 0 2 2 2 0 Septum formation initiator Macoilin PF09726.9 KFO95126.1 - 1.1 7.7 10.8 1.4 7.4 10.8 1.1 1 0 0 1 1 1 0 Macoilin family Fungal_TACC PF12709.7 KFO95126.1 - 1.6 9.2 9.9 0.97 9.9 7.7 1.7 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins 7tm_1 PF00001.21 KFO95127.1 - 1.4e-42 145.8 25.5 1.7e-42 145.5 25.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFO95127.1 - 1.6e-08 34.6 25.1 3.4e-08 33.5 25.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFO95127.1 - 0.077 12.7 16.5 3.4 7.3 16.5 2.3 1 1 0 1 1 1 0 Olfactory receptor Git3 PF11710.8 KFO95127.1 - 1.7 8.4 25.1 0.51 10.1 16.4 2.2 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 CNH PF00780.22 KFO95128.1 - 2.7e-21 76.4 0.0 3.2e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 CNH domain zf-C2H2 PF00096.26 KFO95129.1 - 3.1e-14 52.5 10.1 1e-07 32.0 2.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO95129.1 - 1.5e-10 41.0 1.0 1.5e-10 41.0 1.0 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFO95129.1 - 7.7e-09 35.7 9.3 0.00018 22.1 1.9 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger DUF3850 PF12961.7 KFO95129.1 - 0.026 14.6 0.0 0.031 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) FOXP-CC PF16159.5 KFO95129.1 - 0.028 15.0 3.5 0.18 12.5 0.4 2.0 2 0 0 2 2 2 0 FOXP coiled-coil domain zf_C2H2_ZHX PF18387.1 KFO95129.1 - 0.06 13.0 0.9 0.48 10.1 0.1 2.0 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_6 PF13912.6 KFO95129.1 - 0.072 13.1 0.5 0.072 13.1 0.5 2.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KFO95129.1 - 0.1 12.7 0.3 0.12 12.6 0.3 1.2 1 1 0 1 1 1 0 Aberrant zinc-finger Glyco_hydro_32N PF00251.20 KFO95129.1 - 0.11 12.0 0.0 0.12 11.9 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain Gly-zipper_YMGG PF13441.6 KFO95131.1 - 9.5 6.0 15.5 18 5.1 15.5 1.5 1 1 0 1 1 1 0 YMGG-like Gly-zipper Chibby PF14645.6 KFO95132.1 - 2.9e-05 24.5 0.1 2.9e-05 24.5 0.1 2.9 2 2 1 3 3 3 1 Chibby family Med22 PF06179.12 KFO95132.1 - 0.015 15.5 0.6 0.036 14.3 0.6 1.7 1 1 0 1 1 1 0 Surfeit locus protein 5 subunit 22 of Mediator complex Stomoxyn PF11585.8 KFO95132.1 - 0.18 11.9 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn PRKG1_interact PF15898.5 KFO95132.1 - 1.3 9.9 11.0 2.8 8.9 0.1 3.3 3 1 0 3 3 3 0 cGMP-dependent protein kinase interacting domain 7tm_4 PF13853.6 KFO95133.1 - 6.5e-56 190.1 25.5 7.4e-56 189.9 25.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO95133.1 - 2e-30 106.0 29.3 2.6e-30 105.6 29.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Sushi PF00084.20 KFO95134.1 - 2.9e-15 56.6 15.0 8.9e-10 39.0 3.8 2.1 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) cEGF PF12662.7 KFO95134.1 - 0.015 15.2 1.3 0.015 15.2 1.3 3.4 4 0 0 4 4 4 0 Complement Clr-like EGF-like TRH PF05438.12 KFO95135.1 - 1.4e-65 221.1 15.8 1.5e-62 211.3 11.6 2.0 2 0 0 2 2 2 2 Thyrotropin-releasing hormone (TRH) Chal_sti_synt_C PF02797.15 KFO95135.1 - 4.8e-05 23.4 0.0 0.0001 22.3 0.0 1.5 1 1 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain zf-H2C2_2 PF13465.6 KFO95136.1 - 1.4e-27 94.9 86.1 2e-07 31.1 4.4 10.2 9 2 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFO95136.1 - 2.8e-18 65.3 77.2 0.002 18.4 9.0 8.5 9 0 0 9 9 8 7 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFO95136.1 - 9.4e-16 57.3 12.9 5.9e-08 32.3 0.2 9.2 8 2 0 8 8 8 4 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KFO95136.1 - 1.6e-12 47.1 74.9 0.01 16.6 0.2 8.8 9 0 0 9 9 8 6 C2H2-type zinc finger zf-C2H2_7 PF15269.6 KFO95136.1 - 0.0058 16.7 2.4 0.0058 16.7 2.4 6.6 3 3 4 7 7 6 3 Zinc-finger BolA PF01722.18 KFO95136.1 - 0.02 15.2 7.5 0.98 9.7 0.6 3.2 3 0 0 3 3 3 0 BolA-like protein C1_2 PF03107.16 KFO95136.1 - 0.025 14.9 33.6 12 6.4 0.9 7.9 8 0 0 8 8 8 0 C1 domain DUF678 PF05077.12 KFO95136.1 - 0.033 14.3 0.5 1.6 8.9 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF678) DUF1764 PF08576.10 KFO95136.1 - 0.072 14.0 2.6 0.61 11.0 0.2 2.4 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DUF2225 PF09986.9 KFO95136.1 - 0.078 12.7 0.4 0.078 12.7 0.4 3.8 4 1 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) GAGA PF09237.11 KFO95136.1 - 0.14 12.0 12.6 0.28 11.0 0.3 3.9 4 0 0 4 4 4 0 GAGA factor zinc_ribbon_15 PF17032.5 KFO95136.1 - 5.5 7.8 22.6 2.4 9.0 3.6 4.4 1 1 4 5 5 5 0 zinc-ribbon family zf-C2H2_jaz PF12171.8 KFO95136.1 - 9.7 6.6 0.0 0.35 11.2 1.8 7.6 8 1 0 8 8 7 0 Zinc-finger double-stranded RNA-binding TFIIIC_delta PF12657.7 KFO95137.1 - 1.2e-25 90.6 0.0 1.3e-24 87.1 0.0 2.3 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term Pkinase_Tyr PF07714.17 KFO95138.1 - 5.1e-37 127.6 0.1 6.2e-37 127.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO95138.1 - 5.4e-26 91.5 0.0 6.6e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFO95138.1 - 0.0003 20.8 0.1 0.0006 19.9 0.1 1.5 1 0 0 1 1 1 1 SH2 domain DUF3483 PF11982.8 KFO95138.1 - 0.21 11.2 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) CN_hydrolase PF00795.22 KFO95139.1 - 4.9e-12 45.7 0.0 7.1e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase RRM_1 PF00076.22 KFO95141.1 - 6.9e-23 80.3 0.0 8e-23 80.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFO95141.1 - 0.0021 17.9 0.0 0.0032 17.3 0.0 1.3 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KFO95141.1 - 0.0035 17.3 0.0 0.0045 17.0 0.0 1.2 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.6 KFO95141.1 - 0.13 11.9 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.12 KFO95141.1 - 0.16 11.7 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Calcipressin Transthyretin PF00576.21 KFO95142.1 - 2.6e-13 50.6 0.0 2.8e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family TTR-52 PF01060.23 KFO95142.1 - 0.055 14.2 0.0 0.072 13.8 0.0 1.2 1 0 0 1 1 1 0 Transthyretin-like family DOCK-C2 PF14429.6 KFO95143.1 - 2.2e-36 125.5 0.0 2.6e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DOCK_N PF16172.5 KFO95143.1 - 4.4e-09 35.7 0.0 6.2e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 DOCK N-terminus Methyltransf_11 PF08241.12 KFO95144.1 - 8.9e-11 42.3 0.0 4.5e-10 40.0 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFO95144.1 - 2.8e-07 31.2 0.0 1.7e-06 28.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 KFO95144.1 - 1.1e-05 25.4 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.18 KFO95144.1 - 1.2e-05 24.8 0.0 5.7e-05 22.6 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KFO95144.1 - 3.2e-05 23.8 0.0 6.7e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFO95144.1 - 0.057 14.2 0.0 0.13 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Atg8 PF02991.16 KFO95145.1 - 7.5e-41 138.5 0.1 8.3e-41 138.4 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KFO95145.1 - 2.2e-06 28.0 0.0 2.5e-06 27.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 CTXphi_pIII-N1 PF16710.5 KFO95145.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.3 1 1 0 1 1 1 0 N-terminal N1 domain of Vibrio phage CTXphi pIII Transglut_core PF01841.19 KFO95146.1 - 2.9e-10 40.6 0.7 5.6e-10 39.7 0.1 1.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily Ras PF00071.22 KFO95147.1 - 1.2e-29 103.0 0.0 1.3e-29 102.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO95147.1 - 1e-13 51.6 0.0 1.3e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase CagD PF16567.5 KFO95147.1 - 0.027 14.3 0.0 0.034 13.9 0.0 1.1 1 0 0 1 1 1 0 Pathogenicity island component CagD PDEase_I PF00233.19 KFO95148.1 - 1e-05 25.4 0.4 1.3e-05 25.1 0.4 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HTH_Mga PF08280.11 KFO95148.1 - 0.0033 17.4 0.1 0.0042 17.1 0.1 1.2 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain Acatn PF13000.7 KFO95150.1 - 2.8e-17 62.4 0.4 7.7e-15 54.4 0.0 2.1 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 PQ-loop PF04193.14 KFO95151.1 - 6.4e-20 70.7 3.7 1.2e-19 69.8 3.7 1.5 1 0 0 1 1 1 1 PQ loop repeat DUF4929 PF16283.5 KFO95151.1 - 0.0067 15.5 0.2 0.0081 15.2 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4929) Blt1 PF12754.7 KFO95151.1 - 0.039 14.3 0.2 0.056 13.8 0.2 1.2 1 0 0 1 1 1 0 Blt1 N-terminal domain DUF4500 PF14937.6 KFO95152.1 - 9.5e-37 124.9 0.0 1.1e-36 124.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4500) LRR_8 PF13855.6 KFO95153.1 - 1.7e-42 143.0 52.5 2.3e-12 46.5 2.9 9.5 5 3 5 10 10 10 9 Leucine rich repeat TIR PF01582.20 KFO95153.1 - 3.5e-21 75.8 0.1 6.8e-21 74.9 0.1 1.5 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 KFO95153.1 - 1.5e-18 66.6 54.3 5e-06 26.8 0.9 10.1 4 3 10 14 14 14 11 Leucine Rich repeats (2 copies) TIR_2 PF13676.6 KFO95153.1 - 4.2e-11 43.5 0.0 1.5e-10 41.7 0.0 1.9 2 0 0 2 2 2 1 TIR domain LRR_5 PF13306.6 KFO95153.1 - 6.2e-11 42.4 20.6 2.7e-07 30.6 0.1 5.0 2 2 1 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFO95153.1 - 0.00012 21.6 15.6 0.046 13.2 0.1 4.3 2 1 1 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 KFO95153.1 - 0.00033 20.8 44.5 3.3 8.6 0.2 12.6 13 1 0 13 13 13 2 Leucine Rich Repeat LRR_6 PF13516.6 KFO95153.1 - 0.00068 19.5 44.5 0.85 9.8 0.4 11.3 12 0 0 12 12 12 4 Leucine Rich repeat Col_cuticle_N PF01484.17 KFO95153.1 - 0.59 10.2 4.3 1.9 8.6 4.3 1.9 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Mob1_phocein PF03637.17 KFO95155.1 - 1.1e-26 93.9 2.1 1.3e-26 93.7 2.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family F-box-like PF12937.7 KFO95155.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 F-box-like Clathrin PF00637.20 KFO95156.1 - 6.6e-40 136.3 1.6 3.1e-36 124.4 1.4 2.1 2 0 0 2 2 2 2 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 KFO95156.1 - 1e-05 24.8 0.1 1.8e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Coatomer WD associated region TPR_8 PF13181.6 KFO95156.1 - 0.00059 19.9 0.2 0.49 10.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFO95156.1 - 0.0021 17.8 0.1 0.021 14.7 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFO95156.1 - 0.0051 17.5 0.1 2.3 9.2 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat ChpXY PF10216.9 KFO95156.1 - 0.0095 15.1 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 CO2 hydration protein (ChpXY) TPR_2 PF07719.17 KFO95156.1 - 0.013 15.5 0.3 0.34 11.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO95156.1 - 0.029 14.6 0.1 0.79 10.0 0.1 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KFO95156.1 - 0.093 13.3 0.5 0.34 11.4 0.1 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Mg_trans_NIPA PF05653.14 KFO95157.1 - 2.3e-101 338.8 13.7 2.7e-101 338.6 13.7 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KFO95157.1 - 1.7e-07 31.5 3.2 1.7e-07 31.5 3.2 3.4 2 1 1 3 3 3 2 EamA-like transporter family DUF5392 PF17370.2 KFO95157.1 - 0.37 10.9 4.0 0.25 11.4 1.2 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5392) MgtE PF01769.16 KFO95157.1 - 4.8 7.6 16.6 5.9 7.3 4.0 2.7 1 1 1 2 2 2 0 Divalent cation transporter DUF1129 PF06570.11 KFO95157.1 - 6.3 6.2 6.9 5.6 6.4 3.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) Pox_A9 PF04835.12 KFO95157.1 - 6.8 6.9 8.3 4.3 7.6 0.6 3.3 3 0 0 3 3 3 0 A9 protein conserved region TssN PF17555.2 KFO95157.1 - 7.2 5.9 12.8 13 5.0 12.8 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssN OGFr_N PF04664.13 KFO95158.1 - 7.2e-68 228.2 4.8 9.6e-68 227.8 4.8 1.1 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region VWD PF00094.25 KFO95159.1 - 7.5e-77 257.0 9.8 8.8e-39 133.3 4.2 2.2 2 0 0 2 2 2 2 von Willebrand factor type D domain C8 PF08742.11 KFO95159.1 - 4.7e-40 135.8 11.1 9.8e-23 80.4 2.4 5.4 6 0 0 6 6 6 2 C8 domain TIL PF01826.17 KFO95159.1 - 4.8e-22 78.0 39.2 6.4e-13 48.7 15.8 6.6 7 0 0 7 7 7 2 Trypsin Inhibitor like cysteine rich domain TILa PF12714.7 KFO95159.1 - 1.5e-16 60.1 35.6 1.8e-11 43.8 11.1 5.0 2 2 2 4 4 4 2 TILa domain DUF1521 PF07481.11 KFO95159.1 - 0.18 11.8 0.0 1.4 8.9 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1521) TAFA PF12020.8 KFO95160.1 - 2e-23 82.6 7.1 2.2e-23 82.5 7.1 1.0 1 0 0 1 1 1 1 TAFA family Sugar_tr PF00083.24 KFO95163.1 - 5.3e-21 75.0 5.4 8.3e-21 74.4 5.4 1.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFO95163.1 - 1.4e-13 50.5 2.6 1.6e-13 50.3 2.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-C2H2 PF00096.26 KFO95164.1 - 1e-17 63.5 20.8 2.3e-06 27.8 2.2 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO95164.1 - 1.8e-15 56.6 23.3 1.3e-08 34.8 2.4 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFO95164.1 - 7.6e-12 45.0 19.4 9.1e-05 23.0 1.8 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFO95164.1 - 3.4e-05 23.7 15.6 0.017 15.1 1.4 3.5 3 1 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 KFO95164.1 - 0.0007 20.2 8.6 0.89 10.2 0.2 3.1 1 1 2 3 3 3 3 FOXP coiled-coil domain zf-Di19 PF05605.12 KFO95164.1 - 0.00079 19.7 2.5 0.00079 19.7 2.5 2.3 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 KFO95164.1 - 0.0035 17.6 5.0 0.0054 17.0 4.8 1.5 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KFO95164.1 - 0.02 15.1 1.9 3.9 7.6 0.2 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger zf_C2H2_ZHX PF18387.1 KFO95164.1 - 0.02 14.5 5.0 0.41 10.3 0.8 2.7 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_9 PF16293.5 KFO95164.1 - 0.032 14.1 0.5 0.081 12.8 0.3 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-LYAR PF08790.11 KFO95164.1 - 0.054 13.4 3.0 3.5 7.6 0.1 2.8 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 KFO95164.1 - 0.072 12.7 1.4 0.85 9.3 0.1 2.8 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 KFO95164.1 - 0.19 12.1 12.6 0.22 11.8 1.5 3.4 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFO95164.1 - 0.23 11.9 5.4 3.2 8.3 0.8 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFO95164.1 - 0.36 10.6 14.5 1.9 8.3 1.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Peptidase_C14 PF00656.22 KFO95165.1 - 3.4e-56 191.0 0.0 3.9e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Caspase domain 7tm_1 PF00001.21 KFO95166.1 - 5.9e-22 78.2 2.2 8.4e-22 77.8 2.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2385 PF09539.10 KFO95166.1 - 0.021 15.3 0.0 0.045 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) DUF1385 PF07136.11 KFO95166.1 - 0.028 13.7 0.9 0.042 13.1 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1385) DUF1279 PF06916.13 KFO95167.1 - 1.8e-24 86.1 0.3 2.7e-24 85.5 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) HTH_39 PF14090.6 KFO95167.1 - 0.18 11.6 0.0 0.4 10.5 0.0 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain Lebercilin PF15619.6 KFO95168.1 - 0.004 16.8 37.7 0.004 16.8 37.7 8.4 5 3 2 8 8 8 1 Ciliary protein causing Leber congenital amaurosis disease TPR_MLP1_2 PF07926.12 KFO95168.1 - 0.005 16.9 4.8 0.005 16.9 4.8 11.4 6 3 4 10 10 10 3 TPR/MLP1/MLP2-like protein GIT_CC PF16559.5 KFO95168.1 - 0.0073 16.2 0.7 0.0073 16.2 0.7 10.6 12 0 0 12 12 12 2 GIT coiled-coil Rho guanine nucleotide exchange factor CENP-F_leu_zip PF10473.9 KFO95168.1 - 0.0097 15.9 17.0 0.0097 15.9 17.0 11.0 7 3 4 11 11 11 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Vps4_C PF09336.10 KFO95168.1 - 0.03 14.3 0.5 0.18 11.8 0.1 2.6 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain SANT_DAMP1_like PF16282.5 KFO95168.1 - 0.33 11.2 2.3 1.2 9.3 0.2 3.1 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 PgaPase_1 PF06162.12 KFO95169.1 - 0.097 12.4 2.1 3.9 7.2 0.0 2.4 2 1 0 2 2 2 0 Putative pyroglutamyl peptidase PgaPase_1 Dermcidin PF15291.6 KFO95169.1 - 0.22 12.1 3.5 0.23 12.0 1.5 2.0 1 1 1 2 2 2 0 Dermcidin, antibiotic peptide DUF4715 PF15835.5 KFO95169.1 - 1.3 9.1 9.0 0.62 10.1 4.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4715) MCU PF04678.13 KFO95169.1 - 1.5 8.9 12.5 3 7.9 12.1 1.8 1 1 0 1 1 1 0 Mitochondrial calcium uniporter DUF2118 PF09891.9 KFO95169.1 - 2.2 8.2 6.3 6.2 6.8 5.9 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) Peptidase_S46 PF10459.9 KFO95169.1 - 2.6 6.6 11.4 1.3 7.5 9.0 1.6 1 1 0 2 2 2 0 Peptidase S46 YtxH PF12732.7 KFO95169.1 - 6.8 7.3 7.9 60 4.3 7.9 2.6 1 1 0 1 1 1 0 YtxH-like protein BST2 PF16716.5 KFO95169.1 - 7.4 7.2 20.9 0.61 10.7 13.7 2.5 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF1664 PF07889.12 KFO95169.1 - 8.8 6.4 15.0 4.6 7.3 1.7 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) S-AdoMet_synt_M PF02772.16 KFO95170.1 - 4.7e-26 91.4 0.0 7.3e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KFO95170.1 - 1.7e-16 60.7 0.0 2.4e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain PLAT PF01477.23 KFO95171.1 - 1.1e-12 48.6 0.2 1.1e-12 48.5 0.2 1.0 1 0 0 1 1 1 1 PLAT/LH2 domain Pkinase PF00069.25 KFO95172.1 - 2.3e-44 151.7 0.0 2.7e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO95172.1 - 2.3e-22 79.5 0.0 2.7e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFO95172.1 - 7e-08 32.1 0.0 1.1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFO95172.1 - 4.2e-05 22.5 0.1 5.2e-05 22.2 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFO95172.1 - 0.054 13.4 0.1 0.088 12.7 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KFO95172.1 - 0.083 12.2 0.2 0.13 11.6 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KFO95172.1 - 0.1 11.6 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 KFO95172.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain GRASP55_65 PF04495.14 KFO95174.1 - 2.9e-74 247.9 0.0 8.5e-57 191.3 0.0 2.0 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 KFO95174.1 - 2.6e-08 34.1 0.0 0.00018 21.7 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFO95174.1 - 4.5e-08 32.8 0.1 0.0094 15.8 0.0 3.2 3 1 0 3 3 3 2 PDZ domain AMP-binding PF00501.28 KFO95175.1 - 1.6e-09 36.9 0.0 2e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme XK-related PF09815.9 KFO95176.1 - 2.7e-65 220.7 23.8 3e-65 220.5 23.8 1.0 1 0 0 1 1 1 1 XK-related protein HigB_toxin PF09907.9 KFO95176.1 - 0.061 13.5 0.5 0.15 12.3 0.5 1.7 1 0 0 1 1 1 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system DUF4736 PF15883.5 KFO95176.1 - 0.54 10.0 5.2 0.11 12.2 0.4 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4736) DUF4571 PF15137.6 KFO95177.1 - 1.1e-100 335.7 5.5 1.2e-100 335.6 5.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4571) ArlS_N PF18719.1 KFO95177.1 - 0.035 14.3 0.0 0.058 13.6 0.0 1.3 1 0 0 1 1 1 0 ArlS sensor domain LON_substr_bdg PF02190.16 KFO95178.1 - 1.3e-05 25.2 0.6 1.8e-05 24.8 0.6 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain PIP49_C PF12260.8 KFO95179.1 - 3.1e-27 95.4 0.2 1e-26 93.7 0.0 1.8 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 PIP49_N PF14875.6 KFO95179.1 - 1e-10 41.7 0.0 1.4e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 N-term cysteine-rich ER, FAM69 DUF525 PF04379.14 KFO95180.1 - 4.1e-24 84.6 0.1 6e-24 84.1 0.1 1.2 1 0 0 1 1 1 1 ApaG domain Bromodomain PF00439.25 KFO95182.1 - 1.8e-22 79.2 0.6 3.7e-22 78.2 0.6 1.6 1 0 0 1 1 1 1 Bromodomain Fer4_15 PF13459.6 KFO95182.1 - 0.24 12.2 3.3 0.55 11.0 1.7 2.3 2 0 0 2 2 2 0 4Fe-4S single cluster domain BUD22 PF09073.10 KFO95182.1 - 0.44 9.8 13.0 0.65 9.3 13.0 1.2 1 0 0 1 1 1 0 BUD22 Connexin PF00029.19 KFO95183.1 - 3.7e-88 295.3 0.2 4.1e-88 295.1 0.2 1.0 1 0 0 1 1 1 1 Connexin APG6_N PF17675.1 KFO95183.1 - 0.39 11.2 7.6 0.58 10.7 7.6 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region GATase_7 PF13537.6 KFO95184.1 - 6.6e-07 29.3 0.0 4.8e-06 26.5 0.0 2.4 2 1 0 2 2 2 1 Glutamine amidotransferase domain Asn_synthase PF00733.21 KFO95184.1 - 0.00041 20.1 0.0 0.00072 19.3 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_6 PF13522.6 KFO95184.1 - 0.0035 17.6 0.0 0.014 15.5 0.0 2.0 2 1 0 2 2 2 1 Glutamine amidotransferase domain ATP_bind_3 PF01171.20 KFO95184.1 - 0.017 14.9 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 PP-loop family QueC PF06508.13 KFO95184.1 - 0.082 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC SecY PF00344.20 KFO95185.1 - 2.3e-44 151.9 2.0 2.8e-44 151.6 2.0 1.0 1 0 0 1 1 1 1 SecY translocase YlaH PF14036.6 KFO95185.1 - 0.0094 16.3 0.8 0.94 9.8 0.2 2.6 2 0 0 2 2 2 2 YlaH-like protein UQ_con PF00179.26 KFO95186.1 - 1.6e-39 134.7 0.1 1.8e-39 134.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFO95186.1 - 0.001 19.4 0.0 0.0013 19.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KFO95186.1 - 0.0059 16.3 0.0 0.006 16.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KFO95186.1 - 0.039 13.8 0.1 0.057 13.3 0.1 1.3 1 1 0 1 1 1 0 UEV domain Med6 PF04934.14 KFO95187.1 - 3e-12 46.5 0.0 4.3e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component SAM_decarbox PF01536.16 KFO95187.1 - 0.034 13.1 0.0 0.038 13.0 0.0 1.0 1 0 0 1 1 1 0 Adenosylmethionine decarboxylase Ten1_2 PF15490.6 KFO95187.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit LRR_8 PF13855.6 KFO95188.1 - 6.5e-08 32.2 11.3 0.016 14.9 0.8 3.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFO95188.1 - 1.4e-05 25.3 17.8 0.0055 17.1 4.2 3.8 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFO95188.1 - 0.01 15.4 2.1 0.15 11.6 0.4 2.4 1 1 1 3 3 3 0 Leucine-rich repeat LRR_6 PF13516.6 KFO95188.1 - 0.036 14.1 10.3 2.5 8.4 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 KFO95188.1 - 3.5 8.6 13.0 1.5 9.6 0.9 3.8 3 2 0 3 3 3 0 Leucine Rich Repeat PMM PF03332.13 KFO95189.1 - 3.3e-70 236.3 0.4 3.7e-70 236.2 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase TcfC PF16967.5 KFO95189.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 E-set like domain SBP_bac_6 PF13343.6 KFO95189.1 - 0.22 10.9 0.0 0.27 10.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Laminin_EGF PF00053.24 KFO95190.1 - 1e-14 54.4 31.9 7.6e-09 35.6 12.8 2.3 2 0 0 2 2 2 2 Laminin EGF domain EGF_2 PF07974.13 KFO95190.1 - 0.06 13.7 4.1 0.06 13.7 4.1 4.5 5 1 0 5 5 5 0 EGF-like domain 7tm_4 PF13853.6 KFO95193.1 - 6.4e-45 154.0 21.0 7.2e-45 153.9 21.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO95193.1 - 1.9e-27 96.3 24.0 2.4e-27 95.9 24.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Bac_export_2 PF01312.19 KFO95193.1 - 0.038 13.2 5.9 0.049 12.8 5.9 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family C4 PF01413.19 KFO95194.1 - 3.5e-64 214.1 3.7 4.8e-44 149.3 0.6 2.0 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen MFS_1 PF07690.16 KFO95195.1 - 4e-13 49.0 3.1 5.4e-13 48.6 3.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KFO95195.1 - 1e-09 37.5 1.4 1.6e-09 36.9 1.4 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1_like PF12832.7 KFO95195.1 - 0.62 8.9 6.0 3 6.6 0.0 2.4 2 1 1 3 3 3 0 MFS_1 like family DUF89 PF01937.19 KFO95196.1 - 5.4e-93 311.7 0.3 6.1e-93 311.6 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 CLTH PF10607.9 KFO95196.1 - 0.029 14.3 1.5 0.39 10.6 0.1 2.2 1 1 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain UPA_2 PF17809.1 KFO95198.1 - 4e-08 33.2 0.1 7.1e-08 32.4 0.1 1.4 2 0 0 2 2 2 1 UPA domain FYVE_2 PF02318.16 KFO95199.1 - 7.3e-24 84.3 22.2 7.9e-24 84.1 22.2 1.0 1 0 0 1 1 1 1 FYVE-type zinc finger Siva PF05458.12 KFO95199.1 - 0.25 11.0 16.5 0.28 10.9 16.5 1.0 1 0 0 1 1 1 0 Cd27 binding protein (Siva) LRR_8 PF13855.6 KFO95200.1 - 1.9e-23 82.0 26.7 9e-12 44.6 9.5 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFO95200.1 - 1.6e-10 41.0 19.0 0.0013 19.1 2.9 3.6 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRRNT PF01462.18 KFO95200.1 - 4.8e-09 35.7 3.3 4.8e-09 35.7 3.3 2.3 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.6 KFO95200.1 - 1.3e-08 34.9 0.0 4.4e-07 29.9 0.0 2.5 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFO95200.1 - 5.2e-05 22.8 4.3 0.00033 20.2 3.2 2.0 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFO95200.1 - 0.0067 16.8 17.5 0.034 14.7 0.7 5.7 5 0 0 5 5 5 1 Leucine Rich Repeat Shisa PF13908.6 KFO95200.1 - 0.023 15.0 0.2 0.037 14.3 0.2 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator LRR_6 PF13516.6 KFO95200.1 - 2.8 8.2 10.0 52 4.3 0.1 5.0 5 0 0 5 5 5 0 Leucine Rich repeat Pkinase_Tyr PF07714.17 KFO95201.1 - 9.7e-97 323.3 0.0 1.1e-96 323.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO95201.1 - 8.3e-47 159.8 0.0 1e-46 159.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.6 KFO95201.1 - 4.1e-12 46.8 1.3 8.1e-12 45.8 1.3 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Kdo PF06293.14 KFO95201.1 - 0.013 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFO95201.1 - 0.019 14.0 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KFO95201.1 - 0.026 13.3 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SprT-like PF10263.9 KFO95202.1 - 2.1e-07 30.8 0.0 4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 SprT-like family Prp18 PF02840.15 KFO95203.1 - 1.1e-38 132.5 0.1 1.2e-38 132.3 0.1 1.0 1 0 0 1 1 1 1 Prp18 domain Serpin PF00079.20 KFO95204.1 - 1.4e-61 208.9 0.6 1.6e-61 208.7 0.6 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Ets PF00178.22 KFO95205.1 - 1.2e-23 83.4 0.4 2e-23 82.7 0.4 1.4 1 0 0 1 1 1 1 Ets-domain Strabismus PF06638.11 KFO95205.1 - 0.0069 15.1 0.2 0.008 14.9 0.2 1.1 1 0 0 1 1 1 1 Strabismus protein Seadorna_VP6 PF07407.11 KFO95206.1 - 0.042 12.8 1.0 0.046 12.7 1.0 1.0 1 0 0 1 1 1 0 Seadornavirus VP6 protein ZapB PF06005.12 KFO95206.1 - 0.2 12.1 9.1 0.26 11.8 9.1 1.4 1 1 0 1 1 1 0 Cell division protein ZapB Spc7 PF08317.11 KFO95206.1 - 0.26 10.2 5.8 0.28 10.0 5.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FapA PF03961.13 KFO95206.1 - 0.28 9.7 0.8 0.29 9.7 0.8 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A CCDC-167 PF15188.6 KFO95206.1 - 2.1 8.7 7.3 1.9 8.9 5.4 1.8 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Paramyx_P_V_C PF03210.13 KFO95207.1 - 0.02 14.7 0.3 0.026 14.3 0.3 1.3 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal HMMR_C PF15908.5 KFO95207.1 - 0.59 10.4 8.5 0.76 10.0 1.4 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal APG6_N PF17675.1 KFO95207.1 - 1.8 9.1 14.7 2.5 8.6 14.7 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Fib_alpha PF08702.10 KFO95207.1 - 5.3 7.2 7.6 17 5.6 2.9 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family MRP-S35 PF10246.9 KFO95208.1 - 3.7e-28 97.6 0.0 3.9e-28 97.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein MRP-S35 RANK_CRD_2 PF18278.1 KFO95209.1 - 2.5e-28 97.9 8.1 2.5e-28 97.9 8.1 2.5 2 0 0 2 2 2 1 Receptor activator of the NF-KB cysteine-rich repeat domain 2 TNFR_c6 PF00020.18 KFO95209.1 - 8.1e-16 58.1 39.5 1e-05 25.8 0.4 4.2 4 0 0 4 4 4 4 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.13 KFO95209.1 - 0.0017 18.1 0.8 0.0017 18.1 0.8 3.7 3 2 0 3 3 3 1 Putative ephrin-receptor like Catalase PF00199.19 KFO95210.1 - 4.5e-149 496.7 0.0 5e-149 496.6 0.0 1.0 1 0 0 1 1 1 1 Catalase LAP1C PF05609.12 KFO95211.1 - 2.6e-103 346.6 0.2 2.8e-103 346.4 0.2 1.0 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) Stap_Strp_tox_C PF02876.17 KFO95211.1 - 0.024 14.9 0.1 0.053 13.8 0.1 1.6 1 1 0 1 1 1 0 Staphylococcal/Streptococcal toxin, beta-grasp domain Tcp11 PF05794.13 KFO95212.1 - 1.3e-111 373.8 0.0 1.5e-111 373.6 0.0 1.0 1 0 0 1 1 1 1 T-complex protein 11 DUF1819 PF08849.11 KFO95212.1 - 0.047 13.5 0.1 0.094 12.5 0.1 1.4 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) UDPGT PF00201.18 KFO95213.1 - 8.8e-47 160.0 0.2 9.6e-47 159.9 0.2 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.18 KFO95214.1 - 6.4e-40 137.4 0.1 7e-40 137.3 0.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase HlyIII PF03006.20 KFO95215.1 - 1.3e-72 244.2 21.2 1.5e-72 244.0 21.2 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF3493 PF11998.8 KFO95215.1 - 0.2 11.8 1.4 1.4 9.1 1.4 2.3 1 1 0 1 1 1 0 Low psii accumulation1 / Rep27 MCM PF00493.23 KFO95216.1 - 1.4e-88 295.8 0.0 1.9e-88 295.3 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFO95216.1 - 1.3e-39 134.9 0.3 2.3e-39 134.1 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 KFO95216.1 - 3.4e-19 69.3 1.0 7.5e-19 68.3 1.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFO95216.1 - 2.7e-08 33.4 0.0 1e-05 25.1 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFO95216.1 - 1e-07 32.0 0.0 4.9e-07 29.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFO95216.1 - 1.9e-05 24.6 0.0 3.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFO95216.1 - 0.0055 16.4 0.1 1.9 8.2 0.0 2.8 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA PF00004.29 KFO95216.1 - 0.024 15.1 0.0 0.055 13.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HypA PF01155.19 KFO95216.1 - 0.04 13.9 0.1 0.099 12.7 0.1 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NTPase_1 PF03266.15 KFO95216.1 - 0.062 13.2 0.4 3.4 7.5 0.0 2.6 2 1 1 3 3 3 0 NTPase AAA_7 PF12775.7 KFO95216.1 - 0.12 11.9 0.1 0.52 9.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF3450 PF11932.8 KFO95217.1 - 0.09 12.1 2.0 0.19 11.0 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Galactosyl_T PF01762.21 KFO95218.1 - 8.3e-66 221.5 0.0 1.2e-65 221.0 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Pkinase PF00069.25 KFO95219.1 - 1.3e-50 172.2 0.1 1.5e-50 172.1 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO95219.1 - 1.9e-26 92.9 0.0 2.6e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFO95219.1 - 0.00058 19.3 0.6 0.00087 18.7 0.6 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFO95219.1 - 0.0027 17.7 0.1 0.016 15.1 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFO95219.1 - 0.025 13.9 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KFO95219.1 - 0.12 11.3 0.3 0.14 11.0 0.3 1.1 1 0 0 1 1 1 0 Haspin like kinase domain 7tm_1 PF00001.21 KFO95220.1 - 3.3e-36 125.0 37.4 9.8e-35 120.1 37.4 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFO95220.1 - 1.8e-13 50.9 27.8 2.7e-11 43.7 23.1 2.9 1 1 1 2 2 2 2 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KFO95220.1 - 1.8e-09 37.4 38.2 3.9e-09 36.3 38.2 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFO95220.1 - 0.23 11.1 43.2 1 8.9 39.5 2.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx PH PF00169.29 KFO95221.1 - 1.3e-09 38.5 0.4 9.4e-06 26.1 0.1 2.1 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KFO95221.1 - 3.5e-06 27.4 0.1 0.0015 18.9 0.1 2.1 2 0 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 KFO95221.1 - 0.0008 19.5 0.2 0.18 12.0 0.1 2.1 1 1 1 2 2 2 2 PH domain PH_8 PF15409.6 KFO95221.1 - 0.0066 16.7 0.0 0.084 13.2 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain Serpin PF00079.20 KFO95222.1 - 2e-84 284.0 3.3 2.7e-84 283.6 3.3 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Rad52_Rad22 PF04098.15 KFO95223.1 - 9.3e-49 165.3 0.7 1.6e-48 164.5 0.0 1.7 2 0 0 2 2 2 1 Rad52/22 family double-strand break repair protein MyTH4 PF00784.17 KFO95224.1 - 5.9e-30 103.9 0.5 5.9e-29 100.7 0.1 2.4 2 0 0 2 2 2 1 MyTH4 domain FERM_M PF00373.18 KFO95224.1 - 1.9e-12 47.6 0.9 5.5e-12 46.1 0.9 1.8 1 0 0 1 1 1 1 FERM central domain Pkinase PF00069.25 KFO95225.1 - 7e-24 84.6 0.0 2e-11 43.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFO95225.1 - 4.1e-13 49.2 0.0 1.4e-05 24.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase TackOD1 PF18551.1 KFO95226.1 - 0.014 15.1 0.1 0.019 14.7 0.1 1.1 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 C6_DPF PF10170.9 KFO95227.1 - 2e-24 85.8 1.1 2.2e-24 85.6 1.1 1.0 1 0 0 1 1 1 1 Cysteine-rich domain C1_2 PF03107.16 KFO95227.1 - 0.17 12.2 4.1 1.1 9.6 0.1 2.3 2 1 0 2 2 2 0 C1 domain LRR_8 PF13855.6 KFO95228.1 - 1.9e-65 216.5 41.7 9.2e-16 57.4 3.2 8.2 6 2 4 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 KFO95228.1 - 2.4e-40 135.8 47.3 1.1e-07 32.1 0.9 10.2 4 2 7 12 12 12 12 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFO95228.1 - 3.7e-24 85.1 6.8 6e-07 29.5 0.0 4.8 1 1 5 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFO95228.1 - 3.5e-18 63.3 31.9 0.22 12.2 0.3 13.4 12 3 1 13 13 13 8 Leucine Rich Repeat LRR_9 PF14580.6 KFO95228.1 - 6.3e-15 55.1 14.5 0.0039 16.7 1.7 5.2 1 1 4 5 5 5 5 Leucine-rich repeat LRR_6 PF13516.6 KFO95228.1 - 7.7e-12 44.3 29.3 0.57 10.4 0.5 11.6 12 0 0 12 12 12 4 Leucine Rich repeat LRRNT PF01462.18 KFO95228.1 - 0.35 10.6 4.6 16 5.3 0.0 3.7 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain DHR-2 PF06920.13 KFO95229.1 - 1.7e-55 188.7 0.1 2e-55 188.4 0.1 1.0 1 0 0 1 1 1 1 Dock homology region 2 TPR_7 PF13176.6 KFO95229.1 - 0.11 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat E1-E2_ATPase PF00122.20 KFO95230.1 - 1e-13 51.2 3.0 1.1e-13 51.1 3.0 1.0 1 0 0 1 1 1 1 E1-E2 ATPase AKNA PF12443.8 KFO95231.1 - 0.022 15.4 0.1 0.027 15.1 0.1 1.1 1 0 0 1 1 1 0 AT-hook-containing transcription factor 7tm_4 PF13853.6 KFO95232.1 - 0.0047 16.7 1.2 0.0051 16.6 0.6 1.3 1 1 0 1 1 1 1 Olfactory receptor RRM_5 PF13893.6 KFO95233.1 - 1.2e-54 183.3 0.2 2.1e-49 166.3 0.0 4.1 3 1 1 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KFO95233.1 - 7.7e-17 60.9 0.3 8.8e-05 22.3 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KFO95233.1 - 1.2e-06 28.6 0.1 0.0011 19.2 0.0 2.7 2 0 0 2 2 2 2 RRM-like domain RRM_occluded PF16842.5 KFO95233.1 - 4.6e-05 23.2 0.1 0.26 11.2 0.0 2.6 3 0 0 3 3 3 2 Occluded RNA-recognition motif DUF4523 PF15023.6 KFO95233.1 - 9e-05 22.3 0.0 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) Limkain-b1 PF11608.8 KFO95233.1 - 0.0077 16.3 0.0 3.3 7.8 0.0 2.7 2 0 0 2 2 2 2 Limkain b1 RRM_3 PF08777.11 KFO95233.1 - 0.057 13.5 0.0 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif Ion_trans PF00520.31 KFO95234.1 - 1.4e-43 148.9 11.7 1.7e-43 148.6 11.7 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFO95234.1 - 8.2e-10 38.5 6.2 8.2e-10 38.5 6.2 2.6 3 0 0 3 3 3 1 Ion channel MgtE PF01769.16 KFO95234.1 - 0.058 13.8 0.2 0.058 13.8 0.2 2.7 2 1 1 3 3 3 0 Divalent cation transporter PKD_channel PF08016.12 KFO95234.1 - 0.35 9.5 5.7 1.1 7.8 2.3 2.2 1 1 1 2 2 2 0 Polycystin cation channel TraQ PF09679.10 KFO95235.1 - 0.23 11.4 0.0 0.44 10.5 0.0 1.3 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) DUF1325 PF07039.11 KFO95236.1 - 0.011 15.9 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 SGF29 tudor-like domain Cadherin PF00028.17 KFO95237.1 - 1.6e-16 60.5 0.0 1.9e-13 50.7 0.0 2.2 2 1 0 2 2 2 2 Cadherin domain Cadherin_3 PF16184.5 KFO95237.1 - 0.0032 17.5 0.1 0.0072 16.3 0.1 1.6 2 0 0 2 2 2 1 Cadherin-like Cadherin PF00028.17 KFO95238.1 - 3.8e-17 62.5 0.0 3.1e-14 53.2 0.0 2.1 2 0 0 2 2 2 2 Cadherin domain Cadherin_3 PF16184.5 KFO95238.1 - 0.018 15.0 0.0 0.031 14.3 0.0 1.5 1 1 0 1 1 1 0 Cadherin-like VCBS PF13517.6 KFO95239.1 - 0.086 13.4 0.2 0.086 13.4 0.2 1.2 1 1 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DS PF01916.17 KFO95240.1 - 2.9e-21 76.0 0.0 3.1e-21 75.9 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Ion_trans PF00520.31 KFO95241.1 - 1.1e-10 41.2 0.8 1.2e-10 41.1 0.8 1.0 1 0 0 1 1 1 1 Ion transport protein DUF423 PF04241.15 KFO95241.1 - 0.0096 16.1 0.7 0.011 16.0 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Ras PF00071.22 KFO95242.1 - 7.4e-57 191.5 0.0 8.3e-57 191.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO95242.1 - 8.2e-23 80.9 0.0 1.2e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO95242.1 - 4.5e-10 39.2 0.0 6.5e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFO95242.1 - 0.023 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DAP3 PF10236.9 KFO95242.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Frag1 PF10277.9 KFO95243.1 - 6.5e-14 52.0 7.9 7.1e-14 51.9 7.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Neur_chan_memb PF02932.16 KFO95244.1 - 1.6e-42 146.2 2.4 1e-33 117.4 0.8 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFO95244.1 - 2.5e-40 138.2 0.0 1.2e-32 113.1 0.0 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain WD40 PF00400.32 KFO95245.1 - 5.3e-05 23.9 0.4 0.47 11.4 0.1 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Arrestin_N PF00339.29 KFO95246.1 - 7.4e-42 142.9 0.0 1.8e-36 125.4 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KFO95246.1 - 8.3e-26 91.0 0.4 9.1e-25 87.7 0.2 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain BatD PF13584.6 KFO95246.1 - 0.03 13.1 0.1 0.038 12.8 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance AP3B1_C PF14796.6 KFO95246.1 - 0.03 14.6 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal LDB19 PF13002.7 KFO95246.1 - 0.064 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like CBM49 PF09478.10 KFO95246.1 - 0.17 12.2 0.2 0.32 11.3 0.2 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain CBM49 Pro_isomerase PF00160.21 KFO95248.1 - 9.5e-51 172.2 0.3 1.1e-50 172.1 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PX PF00787.24 KFO95249.1 - 3e-13 49.8 0.2 3.7e-13 49.5 0.2 1.1 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KFO95250.1 - 3.9e-81 272.1 20.9 3.9e-81 272.1 20.9 1.5 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 KFO95250.1 - 5.2e-28 97.3 0.8 2.2e-27 95.3 0.1 2.2 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.9 KFO95250.1 - 9.1e-05 22.0 1.9 0.0027 17.2 1.1 2.4 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein FUSC PF04632.12 KFO95250.1 - 0.052 12.1 5.6 0.082 11.4 5.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2833 PF11090.8 KFO95250.1 - 0.51 10.7 2.3 0.56 10.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2833) Arfaptin PF06456.13 KFO95250.1 - 0.98 8.9 11.8 0.042 13.4 3.5 2.4 2 1 0 2 2 2 0 Arfaptin-like domain HR1 PF02185.16 KFO95250.1 - 1.4 9.1 6.4 1.5 9.0 1.1 2.9 2 1 0 2 2 2 0 Hr1 repeat BLOC1_2 PF10046.9 KFO95250.1 - 3.7 7.9 9.1 5.4 7.4 0.5 3.2 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4349 PF14257.6 KFO95250.1 - 7.5 5.9 9.4 1.6 8.2 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) YgaB PF14182.6 KFO95250.1 - 9 6.8 11.0 0.17 12.3 0.9 3.1 2 2 1 3 3 3 0 YgaB-like protein PAT1 PF09770.9 KFO95251.1 - 3.1e-15 55.6 1.6 3e-12 45.7 0.1 2.3 2 0 0 2 2 2 2 Topoisomerase II-associated protein PAT1 TERB2 PF15101.6 KFO95252.1 - 1.1e-15 58.3 0.0 1.3e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 Telomere-associated protein TERB2 Uroplakin_II PF07353.12 KFO95252.1 - 0.036 13.6 0.1 0.036 13.6 0.1 1.1 1 0 0 1 1 1 0 Uroplakin II Ribosomal_S17e PF00833.18 KFO95253.1 - 3.5e-60 201.3 0.1 4e-60 201.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 CEBP1_N PF16368.5 KFO95254.1 - 2.6e-154 513.2 20.5 3.7e-154 512.8 20.5 1.1 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein 1 N-terminus RRM_7 PF16367.5 KFO95254.1 - 2.7e-36 123.5 0.0 7.7e-36 122.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif CEBP_ZZ PF16366.5 KFO95254.1 - 1.2e-24 86.3 8.4 1.2e-24 86.3 8.4 1.8 2 0 0 2 2 2 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 KFO95254.1 - 2.7e-08 33.5 0.0 0.01 15.7 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-B_box PF00643.24 KFO95254.1 - 2.7 8.2 6.3 5.5 7.2 6.3 1.4 1 0 0 1 1 1 0 B-box zinc finger Adaptin_N PF01602.20 KFO95255.1 - 1.3e-177 591.6 21.4 1.5e-177 591.3 21.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region AP3B1_C PF14796.6 KFO95255.1 - 4.6e-55 185.9 0.0 1e-54 184.8 0.0 1.6 1 0 0 1 1 1 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Cnd1 PF12717.7 KFO95255.1 - 4.5e-23 82.1 9.8 4.4e-19 69.1 0.9 3.7 2 1 0 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFO95255.1 - 7.1e-08 32.7 8.1 0.00022 21.6 0.2 5.2 3 3 2 5 5 5 2 HEAT repeats HEAT PF02985.22 KFO95255.1 - 1.6e-06 27.8 3.1 1.7 9.1 0.0 6.5 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 KFO95255.1 - 0.0036 17.8 3.5 4.3 8.0 0.0 5.4 4 2 3 7 7 7 1 HEAT-like repeat Apt1 PF10351.9 KFO95255.1 - 1.2 7.9 13.4 2.2 7.0 13.4 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Dsh_C PF12316.8 KFO95255.1 - 3.3 8.1 25.2 6 7.2 25.2 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal TFIIF_alpha PF05793.12 KFO95255.1 - 7.9 4.9 29.7 14 4.1 29.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) LRAT PF04970.13 KFO95256.1 - 0.0021 18.4 0.0 0.0022 18.3 0.0 1.2 1 0 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 KFO95256.1 - 0.0039 17.2 0.0 0.0046 17.0 0.0 1.2 1 0 0 1 1 1 1 NlpC/P60 family Hormone_recep PF00104.30 KFO95257.1 - 5.1e-31 107.9 0.0 1.3e-30 106.5 0.0 1.6 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFO95257.1 - 3.9e-28 97.7 14.2 4.5e-28 97.5 12.5 1.9 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Myosin_head PF00063.21 KFO95258.1 - 1.6e-214 714.1 10.5 1.7e-185 618.2 5.6 2.4 2 0 0 2 2 2 2 Myosin head (motor domain) RhoGAP PF00620.27 KFO95258.1 - 7.8e-48 162.2 0.1 1.1e-46 158.4 0.0 2.9 2 0 0 2 2 2 1 RhoGAP domain RA PF00788.23 KFO95258.1 - 1.6e-21 76.7 1.9 2.8e-21 76.0 0.0 2.6 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain IQ PF00612.27 KFO95258.1 - 1.2e-16 58.8 40.0 0.00083 18.9 1.3 6.9 5 1 1 6 6 6 5 IQ calmodulin-binding motif C1_1 PF00130.22 KFO95258.1 - 5e-06 26.3 12.3 9.4e-06 25.4 12.3 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_22 PF13401.6 KFO95258.1 - 0.0017 18.6 0.9 0.071 13.4 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 KFO95258.1 - 0.05 14.0 0.0 0.24 11.8 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 KFO95258.1 - 0.054 12.6 0.0 0.18 10.8 0.0 1.9 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF5320 PF17253.2 KFO95258.1 - 0.49 11.5 3.8 7 7.8 0.1 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5320) APG6_N PF17675.1 KFO95258.1 - 1.2 9.6 23.5 0.014 15.9 1.5 3.8 3 0 0 3 3 3 0 Apg6 coiled-coil region Peptidase_C48 PF02902.19 KFO95259.1 - 2e-13 50.7 0.6 5.3e-13 49.3 0.6 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GRAM PF02893.20 KFO95260.1 - 5e-21 74.7 0.1 1.1e-20 73.7 0.1 1.5 1 0 0 1 1 1 1 GRAM domain PK PF00224.21 KFO95261.1 - 6.2e-170 564.7 4.5 7.4e-170 564.4 4.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KFO95261.1 - 1.1e-34 119.1 0.0 5.8e-34 116.8 0.0 2.3 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KFO95261.1 - 0.00039 19.6 0.2 0.00087 18.5 0.2 1.6 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PARP PF00644.20 KFO95262.1 - 3.6e-13 49.5 0.1 6.7e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ARTD15_N PF18084.1 KFO95262.1 - 3.9e-05 23.8 0.0 0.00011 22.4 0.0 1.7 1 0 0 1 1 1 1 ARTD15 N-terminal domain zf-C4pol PF14260.6 KFO95262.1 - 0.11 13.0 0.1 0.46 11.0 0.0 2.0 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta RRM_1 PF00076.22 KFO95263.1 - 2.8e-37 126.4 0.0 4.2e-18 64.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 KFO95263.1 - 0.016 15.2 0.0 2.2 8.4 0.0 2.8 2 1 0 2 2 2 0 RNA binding domain RRM_7 PF16367.5 KFO95263.1 - 0.041 14.0 0.1 15 5.8 0.0 2.7 2 1 0 2 2 2 0 RNA recognition motif Nup35_RRM_2 PF14605.6 KFO95263.1 - 0.16 12.0 0.0 6.5 6.8 0.0 2.9 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KFO95263.1 - 0.19 11.8 0.0 17 5.5 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif RRM_1 PF00076.22 KFO95264.1 - 9.9e-16 57.3 0.0 1.6e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFO95264.1 - 0.024 14.8 0.0 0.033 14.3 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif Glyco_hydro_20 PF00728.22 KFO95265.1 - 1.3e-84 284.7 0.0 2.4e-84 283.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain IBR PF01485.21 KFO95266.1 - 3.5e-14 52.8 10.1 3.5e-14 52.8 10.1 4.5 4 1 1 5 5 5 1 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 KFO95266.1 - 4.8e-06 26.3 2.6 4.8e-06 26.3 2.6 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFO95266.1 - 0.00015 21.8 20.8 0.0021 18.2 5.1 3.8 4 0 0 4 4 4 2 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KFO95266.1 - 0.00039 20.2 3.8 0.00039 20.2 3.8 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFO95266.1 - 0.00039 20.3 6.1 0.00039 20.3 6.1 3.5 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFO95266.1 - 0.0011 18.9 4.2 0.0011 18.9 4.2 3.3 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_14 PF17978.1 KFO95266.1 - 0.0014 19.0 1.9 0.0014 19.0 1.9 2.2 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 KFO95266.1 - 0.0015 18.9 6.1 0.0015 18.9 6.1 4.0 3 1 0 3 3 3 1 Ring finger domain Med14 PF08638.11 KFO95266.1 - 0.078 12.4 1.1 0.16 11.3 0.3 1.9 2 0 0 2 2 2 0 Mediator complex subunit MED14 OmpH PF03938.14 KFO95266.1 - 0.12 12.7 2.7 0.15 12.4 0.3 2.0 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) ISK_Channel PF02060.15 KFO95267.1 - 1.2e-10 41.1 0.3 1.7e-10 40.6 0.3 1.3 1 1 0 1 1 1 1 Slow voltage-gated potassium channel AMP-binding PF00501.28 KFO95268.1 - 3.3e-102 342.2 0.1 4.4e-102 341.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFO95268.1 - 3.4e-05 24.8 0.1 0.00014 22.8 0.1 2.1 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain DAGAT PF03982.13 KFO95269.1 - 2e-119 397.9 0.1 2.5e-119 397.6 0.1 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase tRNA_synthFbeta PF17759.1 KFO95270.1 - 5.5e-52 176.3 0.0 8.1e-52 175.8 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B3_4 PF03483.17 KFO95270.1 - 2.5e-28 98.9 0.1 4.3e-28 98.1 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain PhetRS_B1 PF18262.1 KFO95270.1 - 4.7e-25 87.6 0.5 5.2e-24 84.3 0.4 2.6 2 1 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B5 PF03484.15 KFO95270.1 - 1.7e-16 60.3 0.0 4.8e-14 52.4 0.0 3.6 3 0 0 3 3 3 1 tRNA synthetase B5 domain Glyco_hydro_77 PF02446.17 KFO95270.1 - 0.039 12.8 0.0 0.055 12.3 0.0 1.1 1 0 0 1 1 1 0 4-alpha-glucanotransferase PAP2 PF01569.21 KFO95271.1 - 4e-16 59.0 3.4 4e-16 59.0 3.4 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KFO95271.1 - 2.7e-06 27.2 2.7 7e-06 25.9 2.7 1.8 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 KFO95271.1 - 0.16 12.1 1.8 0.51 10.5 0.3 2.2 1 1 1 2 2 2 0 Divergent PAP2 family RseC_MucC PF04246.12 KFO95271.1 - 2.5 8.1 0.0 2.5 8.1 0.0 2.7 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC PAX PF00292.18 KFO95272.1 - 1.5e-32 112.2 1.2 7e-23 80.9 0.0 2.3 2 0 0 2 2 2 2 'Paired box' domain Pax7 PF12360.8 KFO95272.1 - 1.7e-25 88.9 6.8 3.4e-25 88.0 6.8 1.5 1 0 0 1 1 1 1 Paired box protein 7 Homeodomain PF00046.29 KFO95272.1 - 7.3e-23 80.2 6.9 1.2e-22 79.5 6.9 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO95272.1 - 0.00028 20.7 1.4 0.00052 19.9 0.7 1.9 2 0 0 2 2 2 1 Homeobox KN domain QLQ PF08880.11 KFO95272.1 - 3.4 7.5 4.5 5.8 6.8 0.1 3.2 3 0 0 3 3 3 0 QLQ Ephrin_lbd PF01404.19 KFO95273.1 - 2.1e-73 246.1 0.0 4.2e-73 245.2 0.0 1.5 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase_Tyr PF07714.17 KFO95273.1 - 4.6e-56 190.0 0.8 1.3e-36 126.3 0.2 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase fn3 PF00041.21 KFO95273.1 - 3.2e-34 117.1 0.4 1e-16 61.1 0.1 3.0 2 0 0 2 2 2 2 Fibronectin type III domain EphA2_TM PF14575.6 KFO95273.1 - 6.2e-25 87.9 0.1 1.3e-24 86.9 0.1 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SAM_2 PF07647.17 KFO95273.1 - 8.5e-21 73.8 0.0 1.6e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pkinase PF00069.25 KFO95273.1 - 2.2e-20 73.1 0.2 5.5e-10 39.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain SAM_1 PF00536.30 KFO95273.1 - 2.7e-18 66.1 0.0 5e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pur_ac_phosph_N PF16656.5 KFO95273.1 - 5.4e-06 26.9 0.4 0.0088 16.6 0.1 2.9 1 1 1 2 2 2 2 Purple acid Phosphatase, N-terminal domain Ephrin_rec_like PF07699.13 KFO95273.1 - 2e-05 24.3 5.4 2e-05 24.3 5.4 3.1 2 2 1 3 3 3 1 Putative ephrin-receptor like fn3_2 PF16893.5 KFO95273.1 - 0.00047 20.3 0.2 1.3 9.2 0.0 3.1 3 0 0 3 3 3 2 Fibronectin type III domain DUF2369 PF10179.9 KFO95273.1 - 0.0039 17.5 0.1 0.015 15.6 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2369) Interfer-bind PF09294.10 KFO95273.1 - 0.018 15.4 0.6 1.7 9.0 0.0 3.2 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.17 KFO95273.1 - 0.019 14.8 0.2 0.14 12.0 0.1 2.3 2 0 0 2 2 2 0 Tissue factor SusE PF14292.6 KFO95273.1 - 0.072 13.3 0.0 1.8 8.8 0.0 2.5 1 1 1 2 2 2 0 SusE outer membrane protein AMP-binding PF00501.28 KFO95274.1 - 1.3e-67 228.3 0.0 1.8e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFO95274.1 - 0.0014 19.5 0.0 0.0027 18.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RIO1 PF01163.22 KFO95275.1 - 1.7e-53 181.0 2.1 1.7e-53 181.0 2.1 1.9 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.11 KFO95275.1 - 1.1e-24 86.4 1.7 1.6e-24 85.9 0.1 2.1 3 0 0 3 3 3 1 Rio2, N-terminal APH PF01636.23 KFO95275.1 - 4.2e-09 36.7 2.5 3.4e-05 23.9 0.4 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KFO95275.1 - 9.7e-08 31.6 2.6 2.7e-06 26.9 2.6 2.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.11 KFO95275.1 - 0.00056 19.6 0.0 0.00098 18.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) PIP49_C PF12260.8 KFO95275.1 - 0.032 13.9 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Glyoxalase_2 PF12681.7 KFO95275.1 - 1.7 8.6 6.7 0.46 10.4 0.1 3.0 4 0 0 4 4 4 0 Glyoxalase-like domain SNF2_N PF00176.23 KFO95276.1 - 1.4e-68 231.2 0.3 3e-68 230.1 0.3 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain CDH1_2_SANT_HL1 PF18375.1 KFO95276.1 - 3.7e-33 114.1 0.0 3.7e-33 114.1 0.0 5.0 4 1 1 5 5 5 1 CDH1/2 SANT-Helical linker 1 Chromo PF00385.24 KFO95276.1 - 1.9e-28 98.1 10.7 4.6e-18 64.9 0.1 4.1 4 0 0 4 4 4 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 KFO95276.1 - 1.7e-26 92.5 2.1 1.7e-26 92.5 2.1 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 KFO95276.1 - 6.8e-20 71.5 0.0 1.8e-19 70.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CHDCT2 PF08074.11 KFO95276.1 - 0.0049 17.1 0.0 0.0049 17.1 0.0 2.8 3 0 0 3 3 3 1 CHDCT2 (NUC038) domain Glyco_transf_29 PF00777.18 KFO95277.1 - 2.7e-77 259.8 0.0 3.2e-77 259.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) OATP PF03137.20 KFO95278.1 - 8.3e-35 120.1 1.2 1.2e-34 119.6 1.2 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF3671 PF12420.8 KFO95278.1 - 0.065 13.3 0.2 0.11 12.6 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function HSM3_C PF18794.1 KFO95278.1 - 0.13 11.8 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 DNA mismatch repair protein HSM3, C terminal domain MFS_1 PF07690.16 KFO95278.1 - 0.18 10.7 5.9 0.26 10.2 5.9 1.5 1 1 0 1 1 1 0 Major Facilitator Superfamily Cu2_monoox_C PF03712.15 KFO95279.1 - 2.9e-43 147.1 0.1 5.3e-43 146.3 0.1 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 KFO95279.1 - 2.1e-25 89.5 0.0 4.9e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain NHL PF01436.21 KFO95279.1 - 3e-21 74.3 6.4 2e-05 24.4 0.1 5.8 5 0 0 5 5 5 4 NHL repeat DUF5128 PF17170.4 KFO95279.1 - 0.012 14.8 0.0 0.029 13.5 0.0 1.6 2 0 0 2 2 2 0 6-bladed beta-propeller BatD PF13584.6 KFO95279.1 - 0.024 13.5 0.1 0.036 12.9 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance P16-Arc PF04699.14 KFO95279.1 - 0.15 12.5 1.1 0.36 11.3 1.1 1.5 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Orf78 PF06024.12 KFO95279.1 - 0.16 12.3 0.0 0.42 10.9 0.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) Shisa PF13908.6 KFO95279.1 - 0.23 11.7 0.7 0.44 10.8 0.0 1.7 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Integrase_H2C2 PF17921.1 KFO95280.1 - 1.1e-16 60.6 0.8 2.6e-16 59.5 0.8 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KFO95280.1 - 1.8e-06 28.1 0.1 9.8e-06 25.8 0.0 2.2 2 1 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 KFO95280.1 - 4.1e-05 23.7 0.5 0.00011 22.4 0.5 1.8 1 0 0 1 1 1 1 H2C2 zinc finger AbiJ_NTD4 PF18863.1 KFO95280.1 - 0.00055 20.4 1.6 0.006 17.1 0.2 2.3 2 0 0 2 2 2 1 AbiJ N-terminal domain 4 bMG6 PF17962.1 KFO95280.1 - 1.5 9.0 4.4 1.4 9.1 0.3 2.3 2 0 0 2 2 2 0 Bacterial macroglobulin domain 6 His_Phos_2 PF00328.22 KFO95281.1 - 9.8e-138 459.7 1.6 1.3e-137 459.2 1.6 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KFO95281.1 - 9.2e-43 144.3 0.4 2.3e-42 143.0 0.4 1.7 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KFO95281.1 - 0.0019 17.8 0.0 0.0038 16.9 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain SPT16 PF08644.11 KFO95281.1 - 0.08 13.1 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) UNC119_bdg PF15435.6 KFO95282.1 - 1.2e-102 341.6 0.3 1.3e-102 341.4 0.3 1.0 1 0 0 1 1 1 1 UNC119-binding protein C5orf30 homologue PH PF00169.29 KFO95283.1 - 5e-31 107.3 0.6 6.9e-18 65.1 0.1 2.8 3 0 0 3 3 3 2 PH domain PDZ PF00595.24 KFO95283.1 - 1.1e-13 51.4 0.0 1.9e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFO95283.1 - 1.8e-10 40.5 0.1 3e-10 39.8 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PH_11 PF15413.6 KFO95283.1 - 1.1e-09 38.6 16.1 4.1e-05 23.9 6.5 4.5 3 2 1 4 4 4 3 Pleckstrin homology domain PH_8 PF15409.6 KFO95283.1 - 1e-07 32.1 2.2 3.3e-06 27.3 0.7 3.0 2 2 0 2 2 2 1 Pleckstrin homology domain PDZ_2 PF13180.6 KFO95283.1 - 1.1e-06 28.9 0.0 2.2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PH_9 PF15410.6 KFO95283.1 - 0.0026 18.1 0.4 4 7.8 0.1 3.5 2 2 1 3 3 3 1 Pleckstrin homology domain PH_3 PF14593.6 KFO95283.1 - 0.013 15.6 0.2 0.22 11.6 0.0 2.5 2 0 0 2 2 2 0 PH domain PH_15 PF17339.2 KFO95283.1 - 0.027 14.3 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 0 PH domain PVL_ORF50 PF07768.11 KFO95283.1 - 0.098 13.0 0.1 0.098 13.0 0.1 1.8 2 0 0 2 2 2 0 PVL ORF-50-like family GATase_4 PF13230.6 KFO95283.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferases class-II TcdB_N PF12918.7 KFO95283.1 - 0.18 12.1 0.5 2.8 8.3 0.1 2.5 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain NUDIX PF00293.28 KFO95284.1 - 4.2e-18 65.7 0.3 2.6e-17 63.1 0.0 2.3 2 1 0 2 2 2 1 NUDIX domain Ank_2 PF12796.7 KFO95284.1 - 1.3e-11 44.9 0.2 3.4e-11 43.6 0.2 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFO95284.1 - 9.3e-10 38.9 1.2 2.8e-07 31.0 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFO95284.1 - 2.5e-09 37.2 0.0 5.1e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) NUDIX-like PF09296.11 KFO95284.1 - 1.1e-06 29.2 0.0 2.3e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KFO95284.1 - 1.3e-06 28.0 3.8 2.4e-06 27.1 3.8 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Ank_3 PF13606.6 KFO95284.1 - 1.1e-05 25.5 0.2 0.00024 21.3 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 KFO95284.1 - 1.2e-05 25.5 0.9 0.00011 22.5 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Yae1_N PF09811.9 KFO95285.1 - 5.9e-18 64.3 63.0 1.8e+04 -27.7 63.0 6.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Tubulin PF00091.25 KFO95286.1 - 1.4e-06 28.7 0.0 1.5e-06 28.6 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin PF00091.25 KFO95288.1 - 5.3e-53 180.2 0.5 1.8e-49 168.7 0.1 2.2 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFO95288.1 - 2.5e-52 176.3 0.0 5.8e-52 175.1 0.0 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFO95288.1 - 0.0017 18.1 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain DnaJ PF00226.31 KFO95290.1 - 1.8e-27 95.2 4.9 2.7e-27 94.7 4.9 1.3 1 0 0 1 1 1 1 DnaJ domain UIM PF02809.20 KFO95290.1 - 0.00046 19.9 4.5 0.00046 19.9 4.5 2.5 2 0 0 2 2 2 1 Ubiquitin interaction motif RPT PF13446.6 KFO95290.1 - 0.019 14.8 0.1 0.041 13.8 0.1 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein DUF3292 PF11696.8 KFO95290.1 - 0.034 12.6 0.0 0.046 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Y_phosphatase PF00102.27 KFO95291.1 - 1.1e-73 247.7 0.0 1.4e-73 247.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFO95291.1 - 0.0095 15.7 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFO95291.1 - 0.033 14.3 0.2 0.77 9.9 0.0 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KFO95291.1 - 0.081 12.9 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Peptidase_M18 PF02127.15 KFO95292.1 - 8.9e-168 558.6 0.0 9.9e-168 558.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KFO95292.1 - 1.5e-07 30.8 0.0 7.4e-06 25.2 0.1 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Filament PF00038.21 KFO95293.1 - 1.7e-115 385.9 45.8 2e-115 385.7 45.8 1.1 1 0 0 1 1 1 1 Intermediate filament protein Filament_head PF04732.14 KFO95293.1 - 1.3e-25 90.1 13.4 1.3e-25 90.1 13.4 1.8 2 0 0 2 2 1 1 Intermediate filament head (DNA binding) region Golgin_A5 PF09787.9 KFO95293.1 - 0.0028 17.2 35.5 0.057 12.9 19.6 2.4 1 1 1 2 2 2 2 Golgin subfamily A member 5 TolA_bind_tri PF16331.5 KFO95293.1 - 0.013 15.5 1.8 0.013 15.5 1.8 6.3 3 1 2 6 6 6 0 TolA binding protein trimerisation Jnk-SapK_ap_N PF09744.9 KFO95293.1 - 0.036 14.3 39.0 0.2 11.8 14.7 4.0 1 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Trimer_CC PF08954.11 KFO95293.1 - 0.055 13.0 0.1 0.055 13.0 0.1 4.3 4 0 0 4 4 4 0 Trimerisation motif Baculo_PEP_C PF04513.12 KFO95293.1 - 0.058 13.4 13.7 1.8 8.6 0.4 3.9 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.8 KFO95293.1 - 0.064 10.8 36.1 0.48 7.9 36.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 KFO95293.1 - 0.067 12.1 39.9 0.026 13.4 6.4 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF1664 PF07889.12 KFO95293.1 - 0.19 11.8 19.9 0.63 10.1 3.2 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) GAS PF13851.6 KFO95293.1 - 0.33 10.3 42.2 1.1 8.6 10.4 4.3 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding KLRAQ PF10205.9 KFO95293.1 - 0.36 11.1 26.4 0.13 12.5 10.8 4.1 2 2 0 2 2 2 0 Predicted coiled-coil domain-containing protein Patched PF02460.18 KFO95293.1 - 0.52 8.3 4.3 0.71 7.9 4.3 1.1 1 0 0 1 1 1 0 Patched family DUF948 PF06103.11 KFO95293.1 - 1 9.7 8.7 25 5.2 0.8 4.2 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF5082 PF16888.5 KFO95293.1 - 1 9.6 26.2 4.2 7.7 0.2 4.8 1 1 2 4 4 4 0 Domain of unknown function (DUF5082) WD40_alt PF14077.6 KFO95293.1 - 1.8 8.5 9.7 31 4.5 1.3 4.5 4 0 0 4 4 3 0 Alternative WD40 repeat motif TPR_MLP1_2 PF07926.12 KFO95293.1 - 2.1 8.4 42.0 3.4 7.8 17.3 4.3 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein KASH_CCD PF14662.6 KFO95293.1 - 2.1 8.1 38.8 18 5.1 15.2 3.6 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF4515 PF14988.6 KFO95293.1 - 2.3 8.0 39.5 0.041 13.7 7.3 3.1 1 1 2 3 3 2 0 Domain of unknown function (DUF4515) CENP-H PF05837.12 KFO95293.1 - 2.6 8.5 31.4 0.25 11.7 1.9 4.4 1 1 4 5 5 5 0 Centromere protein H (CENP-H) TACC_C PF05010.14 KFO95293.1 - 2.8 7.7 36.0 0.26 11.0 6.9 2.3 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal T6PP_N PF18572.1 KFO95293.1 - 4.4 7.2 14.4 0.56 10.1 8.2 2.9 2 2 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain WXG100 PF06013.12 KFO95293.1 - 4.4 7.6 15.8 13 6.1 5.1 4.0 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF573 PF04504.14 KFO95293.1 - 7.4 7.3 8.8 4.9 7.9 0.4 3.8 2 2 2 4 4 4 0 Protein of unknown function, DUF573 I-set PF07679.16 KFO95294.1 - 5.4e-20 71.3 0.0 6.2e-20 71.1 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO95294.1 - 3.4e-13 50.0 0.0 4.7e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFO95294.1 - 2.4e-09 37.3 0.0 2.6e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFO95294.1 - 1.1e-07 32.0 0.0 2.4e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KFO95294.1 - 4.6e-07 30.1 0.0 5.4e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFO95294.1 - 0.00018 21.5 0.0 0.0002 21.4 0.0 1.1 1 0 0 1 1 1 1 C17orf99 Ig domain Ig_6 PF18452.1 KFO95294.1 - 0.00049 19.6 0.0 0.00072 19.1 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain NTP_transferase PF00483.23 KFO95295.1 - 8e-14 51.8 0.0 1.2e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KFO95295.1 - 3.3e-09 36.1 10.5 9.1e-07 28.4 1.6 3.8 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 KFO95295.1 - 0.0025 16.0 0.1 0.0037 15.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 KFO95295.1 - 0.04 13.7 0.3 0.35 10.7 0.4 2.5 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase RhoGAP PF00620.27 KFO95296.1 - 7.6e-37 126.5 0.0 9.4e-37 126.2 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 KFO95296.1 - 1.1e-06 28.5 4.8 2.2e-06 27.4 4.8 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KFO95296.1 - 0.018 15.4 0.5 0.056 13.8 0.5 1.8 1 0 0 1 1 1 0 C1 domain PHD PF00628.29 KFO95296.1 - 0.041 13.8 4.9 0.085 12.8 4.9 1.6 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 KFO95296.1 - 0.42 10.6 5.8 1 9.4 5.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 SNX17_FERM_C PF18116.1 KFO95297.1 - 0.031 14.4 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 Sorting Nexin 17 FERM C-terminal domain ASC PF00858.24 KFO95298.1 - 6.6e-106 354.9 0.0 8.9e-106 354.5 0.0 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DUF4203 PF13886.6 KFO95299.1 - 1.6e-49 168.3 38.3 2e-49 168.0 38.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Wzz PF02706.15 KFO95299.1 - 1.3 9.3 4.2 23 5.4 0.6 3.1 2 1 1 3 3 3 0 Chain length determinant protein I-set PF07679.16 KFO95300.1 - 1.3e-179 582.8 0.0 2e-19 69.5 0.0 18.0 18 0 0 18 18 18 17 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO95300.1 - 3.1e-124 405.8 0.0 5e-11 43.1 0.0 18.0 18 0 0 18 18 18 14 Immunoglobulin domain Ig_2 PF13895.6 KFO95300.1 - 6.6e-86 282.7 0.0 3.2e-08 33.8 0.0 15.2 13 2 3 16 16 15 13 Immunoglobulin domain ig PF00047.25 KFO95300.1 - 1.9e-76 252.3 5.6 3.4e-07 30.4 0.0 17.8 17 2 0 17 17 17 12 Immunoglobulin domain V-set PF07686.17 KFO95300.1 - 1.4e-36 124.9 31.6 0.0016 18.6 0.0 24.0 21 7 1 22 22 21 6 Immunoglobulin V-set domain Izumo-Ig PF16706.5 KFO95300.1 - 1.5e-22 79.5 7.3 0.026 14.6 0.1 14.7 15 0 0 15 15 15 4 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFO95300.1 - 1.5e-19 70.2 3.8 1 9.8 0.0 13.4 14 2 0 14 14 14 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFO95300.1 - 2.4e-16 59.7 3.7 2.5 8.4 0.0 13.1 13 2 0 13 13 13 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFO95300.1 - 3.5e-15 55.9 10.9 0.0031 17.5 0.0 11.0 12 1 0 12 12 11 3 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFO95300.1 - 1.3e-14 54.3 1.1 1.7 9.1 0.0 11.4 12 0 0 12 12 12 2 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFO95300.1 - 1.7e-14 53.1 0.0 0.56 9.8 0.0 9.3 11 0 0 11 11 11 3 Immunoglobulin domain BiPBP_C PF06832.12 KFO95300.1 - 2.1e-09 37.3 3.7 22 5.2 0.0 9.4 10 0 0 10 10 10 0 Penicillin-Binding Protein C-terminus Family Ig_C17orf99 PF17736.1 KFO95300.1 - 1e-06 28.7 0.0 0.014 15.4 0.0 5.5 6 1 0 6 6 6 1 C17orf99 Ig domain Receptor_2B4 PF11465.8 KFO95300.1 - 0.0017 18.5 0.0 30 4.9 0.0 5.9 5 0 0 5 5 5 0 Natural killer cell receptor 2B4 TGF_beta PF00019.20 KFO95301.1 - 1.7e-15 57.8 0.8 1.9e-14 54.5 0.8 2.4 1 1 0 1 1 1 1 Transforming growth factor beta like domain Connexin PF00029.19 KFO95302.1 - 5.4e-96 320.9 0.0 6.1e-96 320.7 0.0 1.0 1 0 0 1 1 1 1 Connexin COX1 PF00115.20 KFO95302.1 - 0.021 13.7 0.1 0.026 13.4 0.1 1.1 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I LIP1 PF15904.5 KFO95303.1 - 3.4e-36 123.5 2.6 8e-36 122.3 2.6 1.7 1 0 0 1 1 1 1 LKB1 serine/threonine kinase interacting protein 1 LRR_8 PF13855.6 KFO95303.1 - 5.3e-11 42.1 21.1 2.8e-05 23.8 5.6 4.3 2 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KFO95303.1 - 2e-10 40.7 21.0 5.3e-06 26.7 0.9 5.6 3 3 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFO95303.1 - 8.2e-07 28.7 2.2 2.5e-06 27.1 2.1 1.8 1 1 0 1 1 1 1 Leucine-rich repeat DUF3801 PF12687.7 KFO95303.1 - 0.019 15.0 0.4 0.043 13.9 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) BESS PF02944.20 KFO95303.1 - 0.29 11.0 1.2 0.48 10.3 0.0 2.1 2 0 0 2 2 2 0 BESS motif LRR_1 PF00560.33 KFO95303.1 - 0.33 11.7 20.0 37 5.4 0.1 7.7 7 1 0 7 7 7 0 Leucine Rich Repeat HCO3_cotransp PF00955.21 KFO95304.1 - 5.5e-204 678.7 23.3 1.4e-200 667.4 23.3 2.3 1 1 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 KFO95304.1 - 2.3e-106 355.5 0.5 2.3e-106 355.5 0.5 2.6 3 0 0 3 3 3 1 Band 3 cytoplasmic domain BUD22 PF09073.10 KFO95304.1 - 1.2e-06 28.2 1.4 1.2e-06 28.2 1.4 1.7 1 1 0 1 1 1 1 BUD22 PTS_EIIA_2 PF00359.22 KFO95304.1 - 0.00017 21.5 0.0 0.00034 20.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 NPR3 PF03666.13 KFO95304.1 - 0.014 14.2 11.3 0.048 12.4 9.7 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 NOA36 PF06524.12 KFO95304.1 - 1.6 7.9 4.4 3.3 7.0 4.4 1.4 1 0 0 1 1 1 0 NOA36 protein Ribosomal_60s PF00428.19 KFO95304.1 - 2.3 8.9 16.8 2.5 8.7 0.0 3.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein TFB6 PF17110.5 KFO95304.1 - 4.3 7.0 6.7 36 4.0 0.0 2.9 3 0 0 3 3 3 0 Subunit 11 of the general transcription factor TFIIH DUF1754 PF08555.10 KFO95304.1 - 8.4 7.3 22.4 4.4 8.2 11.8 2.7 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Lectin_C PF00059.21 KFO95305.1 - 9e-134 438.2 75.6 8.9e-20 71.4 0.3 11.9 12 1 0 12 12 12 10 Lectin C-type domain fn2 PF00040.19 KFO95305.1 - 6e-15 55.2 8.4 6.4e-15 55.2 5.9 2.6 2 0 0 2 2 2 1 Fibronectin type II domain UL45 PF05473.12 KFO95305.1 - 7.9e-10 38.7 27.9 0.017 14.8 0.0 10.0 9 2 2 11 11 11 5 UL45 protein, carbohydrate-binding C-type lectin-like Ricin_B_lectin PF00652.22 KFO95305.1 - 0.0045 17.2 1.4 0.0045 17.2 1.4 3.9 4 0 0 4 4 4 1 Ricin-type beta-trefoil lectin domain MARVEL PF01284.23 KFO95305.1 - 0.044 13.8 0.4 0.1 12.6 0.4 1.6 1 0 0 1 1 1 0 Membrane-associating domain Xlink PF00193.17 KFO95305.1 - 0.5 10.8 18.4 39 4.7 0.0 9.0 10 1 0 10 10 10 0 Extracellular link domain Integrin_beta PF00362.18 KFO95306.1 - 5.9e-110 366.8 0.0 9.1e-110 366.2 0.0 1.3 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_b_cyt PF08725.11 KFO95306.1 - 3.4e-19 68.2 0.2 5.5e-19 67.6 0.2 1.4 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.12 KFO95306.1 - 5.3e-13 49.3 6.3 5.3e-13 49.3 6.3 3.8 3 2 1 4 4 4 1 Integrin beta tail domain I-EGF_1 PF18372.1 KFO95306.1 - 2.7e-11 43.3 7.7 2.7e-11 43.3 7.7 6.5 7 0 0 7 7 7 4 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 KFO95306.1 - 6.5e-10 39.2 93.5 0.00013 22.3 18.2 7.1 5 2 2 7 7 7 4 EGF-like domain RRM_1 PF00076.22 KFO95307.1 - 4.4e-33 112.9 0.0 2.9e-16 59.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KFO95307.1 - 0.00076 19.7 0.0 0.95 9.7 0.0 2.3 2 0 0 2 2 2 2 BRCA1-associated protein 2 RRM_7 PF16367.5 KFO95307.1 - 0.14 12.3 0.0 15 5.8 0.0 2.5 2 1 0 2 2 2 0 RNA recognition motif JAB PF01398.21 KFO95308.1 - 1.1e-32 112.4 0.1 3e-32 111.1 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KFO95308.1 - 5e-16 59.1 1.3 8.8e-16 58.3 1.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KFO95308.1 - 2.3e-06 27.4 0.0 4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain T-box_assoc PF16176.5 KFO95309.1 - 4.1e-89 298.5 1.1 7.7e-89 297.6 1.1 1.5 1 0 0 1 1 1 1 T-box transcription factor-associated T-box PF00907.22 KFO95309.1 - 3.9e-15 56.6 0.1 1.2e-06 28.9 0.0 2.2 2 0 0 2 2 2 2 T-box HCO3_cotransp PF00955.21 KFO95310.1 - 4.7e-247 820.8 5.3 5.9e-247 820.5 5.3 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 KFO95310.1 - 5.4e-106 354.3 0.0 7.3e-106 353.9 0.0 1.2 1 0 0 1 1 1 1 Band 3 cytoplasmic domain Hormone_2 PF00123.20 KFO95311.1 - 2.1e-45 152.2 3.5 1.6e-14 53.5 0.1 3.2 3 0 0 3 3 3 3 Peptide hormone Lipoprotein_10 PF03202.13 KFO95311.1 - 0.0002 21.8 3.4 2 8.9 0.2 3.8 3 1 1 4 4 4 2 Putative mycoplasma lipoprotein, C-terminal region SBP_bac_8 PF13416.6 KFO95311.1 - 0.017 14.9 0.1 9.6 5.9 0.0 3.0 3 0 0 3 3 3 0 Bacterial extracellular solute-binding protein Sa_NUDIX PF18167.1 KFO95311.1 - 0.22 11.3 1.7 10 5.9 0.3 2.6 1 1 2 3 3 3 0 SMODS-associated NUDIX domain DPPIV_N PF00930.21 KFO95312.1 - 1.8e-98 329.6 8.2 2.5e-98 329.1 8.2 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KFO95312.1 - 2.5e-57 193.8 1.2 4.2e-57 193.0 1.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_rep PF18811.1 KFO95312.1 - 1.2e-07 31.4 0.0 2.5e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) low complexity region Peptidase_S15 PF02129.18 KFO95312.1 - 0.00017 21.3 3.3 0.00062 19.5 0.3 2.3 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 KFO95312.1 - 0.00026 20.6 0.0 0.0008 19.0 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family LIP PF03583.14 KFO95312.1 - 0.00032 20.1 0.3 0.0007 19.0 0.3 1.5 1 0 0 1 1 1 1 Secretory lipase Esterase_phd PF10503.9 KFO95312.1 - 0.00045 19.8 0.0 0.00067 19.2 0.0 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 KFO95312.1 - 0.0017 19.0 0.0 0.0036 18.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.13 KFO95312.1 - 0.0028 16.2 0.2 0.34 9.4 0.1 2.9 2 1 1 3 3 3 1 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 KFO95312.1 - 0.0046 16.3 0.5 1.2 8.3 0.1 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KFO95312.1 - 0.0057 16.5 1.4 0.57 9.9 0.4 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 KFO95312.1 - 0.02 14.6 0.0 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase (FSH1) AXE1 PF05448.12 KFO95312.1 - 0.023 13.4 0.0 0.089 11.4 0.0 1.9 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Prot_inhib_II PF02428.15 KFO95312.1 - 0.058 13.8 2.1 0.12 12.9 2.1 1.5 1 0 0 1 1 1 0 Potato type II proteinase inhibitor family ANAPC4_WD40 PF12894.7 KFO95312.1 - 0.067 13.5 0.0 9.1 6.7 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RIG-I_C PF18119.1 KFO95313.1 - 1.4e-36 125.6 6.7 1.4e-36 125.6 6.7 2.8 3 0 0 3 3 3 1 RIG-I receptor C-terminal domain RIG-I_C-RD PF11648.8 KFO95313.1 - 1.7e-36 125.0 2.7 1.7e-36 125.0 2.7 2.7 2 0 0 2 2 2 1 C-terminal domain of RIG-I CARD_2 PF16739.5 KFO95313.1 - 1.2e-30 105.4 0.1 3.5e-20 71.8 0.0 2.7 2 0 0 2 2 2 2 Caspase recruitment domain ResIII PF04851.15 KFO95313.1 - 2e-19 70.3 0.0 2e-19 70.3 0.0 3.0 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFO95313.1 - 1.3e-18 67.4 1.9 3.3e-17 62.8 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFO95313.1 - 2.5e-16 59.9 0.2 1.1e-15 57.8 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase CARD PF00619.21 KFO95313.1 - 1.5e-09 37.7 0.3 4.6e-07 29.8 0.1 2.8 2 0 0 2 2 2 1 Caspase recruitment domain SWI2_SNF2 PF18766.1 KFO95313.1 - 5.2e-07 29.6 0.8 1.9e-06 27.7 0.0 2.3 2 1 0 2 2 2 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 KFO95313.1 - 0.0035 17.6 0.2 0.044 14.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KFO95313.1 - 0.011 16.1 0.1 0.24 11.7 0.1 2.9 2 1 0 2 2 2 0 AAA domain DUF3638 PF12340.8 KFO95313.1 - 0.021 14.2 0.2 0.054 12.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3638) zf-B_box PF00643.24 KFO95313.1 - 2.1 8.6 6.1 1.1 9.4 0.7 3.0 3 0 0 3 3 3 0 B-box zinc finger Ion_trans PF00520.31 KFO95314.1 - 3.9e-36 124.5 3.6 5.4e-36 124.1 3.6 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KFO95314.1 - 1.5e-12 47.4 0.0 2.9e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KFO95314.1 - 1.1e-11 44.5 0.0 1.1e-11 44.5 0.0 1.9 2 0 0 2 2 2 1 Ion channel BACK PF07707.15 KFO95314.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 BTB And C-terminal Kelch baeRF_family6 PF18848.1 KFO95314.1 - 0.12 12.7 0.1 0.26 11.7 0.1 1.5 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 6 AAA PF00004.29 KFO95315.1 - 1.6e-24 86.8 0.0 2.7e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KFO95315.1 - 4.7e-07 29.7 0.0 1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 KFO95315.1 - 8.5e-05 22.6 0.0 0.00022 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 KFO95315.1 - 8.8e-05 22.2 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KFO95315.1 - 0.0033 17.8 0.0 0.0097 16.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KFO95315.1 - 0.024 14.4 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFO95315.1 - 0.038 14.3 0.1 0.075 13.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 KFO95315.1 - 0.16 11.2 0.2 0.29 10.3 0.0 1.4 2 0 0 2 2 2 0 TIP49 P-loop domain BPS PF08947.10 KFO95316.1 - 5.6e-29 99.7 0.5 1.5e-28 98.4 0.5 1.7 1 0 0 1 1 1 1 BPS (Between PH and SH2) SH2 PF00017.24 KFO95316.1 - 9.6e-17 60.9 0.1 2e-16 59.8 0.1 1.6 1 0 0 1 1 1 1 SH2 domain RA PF00788.23 KFO95316.1 - 1.4e-13 51.2 0.1 4.1e-13 49.8 0.1 1.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain PH PF00169.29 KFO95316.1 - 9.6e-11 42.1 0.2 3.4e-10 40.4 0.1 2.1 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 KFO95316.1 - 0.12 12.7 0.1 0.41 11.0 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain Cobl PF09469.10 KFO95317.1 - 8.3e-43 144.6 0.5 2.4e-42 143.1 0.5 1.8 1 0 0 1 1 1 1 Cordon-bleu ubiquitin-like domain RBD PF02196.15 KFO95317.1 - 2.9e-07 30.5 0.2 0.022 14.8 0.1 2.6 2 0 0 2 2 2 2 Raf-like Ras-binding domain TUG-UBL1 PF11470.8 KFO95317.1 - 0.019 15.1 0.4 0.12 12.7 0.1 2.4 2 0 0 2 2 2 0 TUG ubiquitin-like domain Aa_trans PF01490.18 KFO95318.1 - 1.8e-64 218.0 29.8 2e-64 217.8 29.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KFO95318.1 - 2.7e-06 26.7 13.2 2.7e-06 26.7 13.2 2.3 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family EI24 PF07264.11 KFO95318.1 - 0.071 13.4 14.2 2 8.6 0.8 3.0 1 1 1 2 2 2 0 Etoposide-induced protein 2.4 (EI24) DUF485 PF04341.12 KFO95318.1 - 0.3 11.1 0.1 0.3 11.1 0.1 4.9 6 0 0 6 6 6 0 Protein of unknown function, DUF485 Neurensin PF14927.6 KFO95318.1 - 1.6 8.5 0.0 1.6 8.5 0.0 3.4 4 0 0 4 4 4 0 Neurensin DUF2371 PF10177.9 KFO95318.1 - 4.1 7.6 11.5 0.61 10.3 0.2 3.6 3 1 0 3 3 3 0 Uncharacterised conserved protein (DUF2371) Ion_trans PF00520.31 KFO95319.1 - 1.1e-239 791.1 103.6 2.1e-79 266.2 17.3 5.1 4 1 1 5 5 5 5 Ion transport protein Na_trans_cytopl PF11933.8 KFO95319.1 - 1.2e-81 273.6 9.7 1.2e-81 273.6 9.7 1.7 2 0 0 2 2 1 1 Cytoplasmic domain of voltage-gated Na+ ion channel Na_trans_assoc PF06512.13 KFO95319.1 - 1.4e-65 221.4 1.6 1.4e-65 221.4 1.6 3.7 4 0 0 4 4 3 1 Sodium ion transport-associated PKD_channel PF08016.12 KFO95319.1 - 7.3e-05 21.6 0.6 7.3e-05 21.6 0.6 9.9 6 4 4 10 10 9 6 Polycystin cation channel GPHH PF16905.5 KFO95319.1 - 0.00011 21.9 0.0 0.00021 21.0 0.0 1.6 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated IQ PF00612.27 KFO95319.1 - 0.0012 18.5 0.9 0.0032 17.1 0.9 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif ATP-synt_B PF00430.18 KFO95319.1 - 0.0012 18.9 4.1 0.0012 18.9 4.1 3.4 4 0 0 4 4 2 1 ATP synthase B/B' CF(0) Neur_chan_memb PF02932.16 KFO95319.1 - 0.027 14.5 0.1 0.027 14.5 0.1 5.3 7 0 0 7 7 7 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 KFO95319.1 - 0.051 12.8 0.1 0.051 12.8 0.1 3.1 3 0 0 3 3 2 0 ZIP Zinc transporter CHAD PF05235.14 KFO95319.1 - 3.3 7.6 6.0 8.6 6.3 6.0 1.7 1 0 0 1 1 1 0 CHAD domain TMEM51 PF15345.6 KFO95319.1 - 9.5 6.0 7.6 27 4.5 1.2 2.8 2 0 0 2 2 2 0 Transmembrane protein 51 CSRNP_N PF16019.5 KFO95320.1 - 3.4e-104 347.5 7.4 3.4e-104 347.5 7.4 2.4 2 0 0 2 2 2 1 Cysteine/serine-rich nuclear protein N-terminus Nop25 PF09805.9 KFO95320.1 - 0.01 16.3 7.0 0.74 10.3 0.1 2.7 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Spt5_N PF11942.8 KFO95320.1 - 0.017 16.1 6.0 0.017 16.1 6.0 3.3 3 1 1 4 4 4 0 Spt5 transcription elongation factor, acidic N-terminal Nop14 PF04147.12 KFO95320.1 - 1.6 6.9 19.6 0.033 12.4 9.2 2.1 2 0 0 2 2 2 0 Nop14-like family GOLD_2 PF13897.6 KFO95320.1 - 3.5 8.1 7.4 0.73 10.3 3.2 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking BUD22 PF09073.10 KFO95320.1 - 8.9 5.5 17.5 2.6 7.3 8.5 2.2 2 0 0 2 2 2 0 BUD22 Glycos_transf_2 PF00535.26 KFO95321.1 - 1.1e-34 119.7 0.0 2e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFO95321.1 - 3.8e-25 88.6 0.6 6.2e-25 87.9 0.6 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 KFO95321.1 - 5.7e-09 35.5 0.0 3.2e-08 33.1 0.1 2.0 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 KFO95321.1 - 4.3e-05 23.5 0.0 8.4e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KFO95321.1 - 0.00012 21.6 0.0 0.036 13.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 TPR_19 PF14559.6 KFO95322.1 - 6.3e-58 193.2 53.1 3.9e-06 27.3 0.3 17.3 13 4 6 19 19 19 13 Tetratricopeptide repeat TPR_2 PF07719.17 KFO95322.1 - 3e-41 136.2 68.4 1.5e-05 24.7 0.0 22.9 23 1 1 24 24 23 9 Tetratricopeptide repeat TPR_14 PF13428.6 KFO95322.1 - 2.1e-37 124.6 38.7 2.3e-05 24.8 0.0 21.3 14 7 8 23 23 23 7 Tetratricopeptide repeat TPR_16 PF13432.6 KFO95322.1 - 1.5e-33 115.1 21.6 4.6e-06 27.2 0.0 16.0 15 3 1 16 16 16 5 Tetratricopeptide repeat TPR_1 PF00515.28 KFO95322.1 - 2.1e-27 93.7 70.5 4.2e-05 23.2 0.2 19.2 20 0 0 20 20 18 7 Tetratricopeptide repeat TPR_8 PF13181.6 KFO95322.1 - 1.3e-25 87.4 49.1 0.00087 19.3 0.1 14.9 16 0 0 16 16 14 9 Tetratricopeptide repeat TPR_7 PF13176.6 KFO95322.1 - 5.7e-19 66.7 36.8 0.00063 19.6 0.0 14.7 17 0 0 17 17 16 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO95322.1 - 2e-18 66.4 61.5 0.00074 19.7 1.8 12.8 8 5 7 15 15 14 8 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KFO95322.1 - 4.1e-17 61.6 37.0 9.5e-06 25.2 0.0 14.0 12 3 3 15 15 15 5 TPR repeat TPR_12 PF13424.6 KFO95322.1 - 2.1e-14 53.6 57.9 0.0028 17.9 0.1 15.8 13 3 2 15 15 15 6 Tetratricopeptide repeat TPR_17 PF13431.6 KFO95322.1 - 5.9e-14 51.3 25.9 0.0051 17.1 0.4 13.8 16 0 0 16 16 13 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFO95322.1 - 3.2e-12 46.2 63.7 0.07 13.8 0.0 19.6 23 0 0 23 23 18 2 Tetratricopeptide repeat TPR_21 PF09976.9 KFO95322.1 - 8.9e-09 35.3 30.9 0.14 11.9 0.2 8.2 6 2 1 8 8 8 6 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 KFO95322.1 - 2.9e-07 30.5 16.3 0.13 12.5 0.0 8.0 10 0 0 10 10 7 3 Tetratricopeptide repeat PPR PF01535.20 KFO95322.1 - 1.5e-05 24.9 13.1 1.2e+02 3.2 0.0 11.8 13 0 0 13 13 11 0 PPR repeat TPR_15 PF13429.6 KFO95322.1 - 2e-05 24.0 36.5 0.03 13.5 0.2 8.4 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFO95322.1 - 4.8e-05 23.1 30.3 0.29 11.1 0.1 11.9 14 0 0 14 14 12 1 Tetratricopeptide repeat TPR_4 PF07721.14 KFO95322.1 - 0.00013 22.3 24.4 0.032 14.9 2.0 9.0 9 0 0 9 9 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFO95322.1 - 0.00069 19.6 31.6 0.16 12.1 0.2 10.9 11 1 1 12 12 10 1 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.7 KFO95322.1 - 0.00098 19.2 3.1 5.9 6.9 0.0 5.2 4 1 0 4 4 4 0 Domain of Unknown Function (DUF3856) PPR_1 PF12854.7 KFO95322.1 - 0.001 18.7 0.3 40 4.0 0.0 6.2 8 0 0 8 8 7 0 PPR repeat TPR_20 PF14561.6 KFO95322.1 - 0.0011 19.3 33.8 11 6.5 0.0 11.1 9 1 4 13 13 11 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KFO95322.1 - 0.0015 19.0 21.7 0.14 12.7 0.4 7.8 6 1 3 9 9 7 1 Alkyl sulfatase dimerisation HrpB1_HrpK PF09613.10 KFO95322.1 - 0.0039 16.8 18.3 0.074 12.7 0.1 8.4 7 1 2 9 9 9 1 Bacterial type III secretion protein (HrpB1_HrpK) SPOB_a PF14689.6 KFO95322.1 - 0.0078 15.9 4.3 1.7 8.4 0.0 5.6 6 0 0 6 6 6 1 Sensor_kinase_SpoOB-type, alpha-helical domain DUF2225 PF09986.9 KFO95322.1 - 0.053 13.2 20.3 0.6 9.8 0.6 6.5 7 1 0 7 7 6 0 Uncharacterized protein conserved in bacteria (DUF2225) BTAD PF03704.17 KFO95322.1 - 0.091 13.2 20.2 2.4 8.6 0.2 6.8 4 2 4 8 8 7 0 Bacterial transcriptional activator domain TPR_MalT PF17874.1 KFO95322.1 - 0.21 10.9 47.1 0.0085 15.5 13.3 7.6 5 2 2 9 9 9 0 MalT-like TPR region Tcf25 PF04910.14 KFO95322.1 - 0.33 10.0 12.8 0.62 9.1 0.4 5.1 6 0 0 6 6 6 0 Transcriptional repressor TCF25 PPR_2 PF13041.6 KFO95322.1 - 0.53 10.5 7.5 1.1e+02 3.1 0.0 6.9 8 0 0 8 8 5 0 PPR repeat family Wzy_C_2 PF11846.8 KFO95322.1 - 0.54 10.1 10.0 4.4 7.2 0.1 5.3 5 1 2 7 7 7 0 Virulence factor membrane-bound polymerase, C-terminal SNAP PF14938.6 KFO95322.1 - 3.2 7.1 32.5 0.22 10.9 2.7 6.5 3 2 3 6 6 6 0 Soluble NSF attachment protein, SNAP Ion_trans PF00520.31 KFO95323.1 - 3.6e-252 832.0 103.6 1.2e-81 273.5 15.8 4.1 4 0 0 4 4 4 4 Ion transport protein Na_trans_cytopl PF11933.8 KFO95323.1 - 1.4e-85 286.5 7.8 1.4e-85 286.5 7.8 1.8 2 0 0 2 2 2 1 Cytoplasmic domain of voltage-gated Na+ ion channel Na_trans_assoc PF06512.13 KFO95323.1 - 5.9e-63 212.8 5.9 5.9e-63 212.8 5.9 2.7 2 0 0 2 2 2 1 Sodium ion transport-associated PKD_channel PF08016.12 KFO95323.1 - 6.9e-10 38.2 84.0 9.8e-05 21.2 0.3 9.3 6 4 4 10 10 10 7 Polycystin cation channel GPHH PF16905.5 KFO95323.1 - 0.00019 21.1 0.1 0.00036 20.2 0.1 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated IQ PF00612.27 KFO95323.1 - 0.014 15.1 0.4 0.036 13.9 0.4 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif SieB PF14163.6 KFO95323.1 - 0.049 13.1 5.7 0.28 10.7 0.7 3.4 2 0 0 2 2 2 0 Super-infection exclusion protein B CytochromB561_N PF09786.9 KFO95323.1 - 0.049 12.6 3.2 0.06 12.3 0.8 2.3 2 0 0 2 2 2 0 Cytochrome B561, N terminal Abhydrolase_9_N PF15420.6 KFO95323.1 - 0.2 11.7 1.3 21 5.0 0.2 3.1 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Lustrin_cystein PF14625.6 KFO95323.1 - 2.1 8.8 5.7 0.23 11.9 0.4 2.2 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain Ion_trans PF00520.31 KFO95324.1 - 9.8e-63 211.6 33.8 2.4e-54 184.2 22.4 2.3 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 KFO95324.1 - 5.9e-07 28.5 23.7 2.1e-05 23.4 1.1 3.3 2 1 1 3 3 3 3 Polycystin cation channel GPHH PF16905.5 KFO95324.1 - 2.1e-06 27.4 0.0 3.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated IQ PF00612.27 KFO95324.1 - 0.0005 19.6 0.5 0.0013 18.3 0.5 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Hydrolase_4 PF12146.8 KFO95325.1 - 6.9e-57 192.5 0.0 7.8e-57 192.3 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFO95325.1 - 1.6e-09 37.8 0.0 1.6e-05 24.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFO95325.1 - 8.1e-06 25.5 0.0 0.014 14.8 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KFO95325.1 - 2.6e-05 24.9 0.0 3.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KFO95325.1 - 3e-05 23.8 0.0 3.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KFO95325.1 - 0.00018 21.4 0.0 0.15 11.8 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 KFO95325.1 - 0.0002 21.2 0.0 0.00042 20.2 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) DLH PF01738.18 KFO95325.1 - 0.00034 20.2 0.0 0.018 14.6 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family PGAP1 PF07819.13 KFO95325.1 - 0.0005 19.8 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 KFO95325.1 - 0.0099 16.0 0.0 0.037 14.1 0.0 1.8 2 1 0 2 2 2 1 Thioesterase domain LIP PF03583.14 KFO95325.1 - 0.015 14.6 0.0 0.052 12.9 0.0 1.8 1 1 1 2 2 2 0 Secretory lipase DUF1350 PF07082.11 KFO95325.1 - 0.025 13.8 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) Abhydrolase_5 PF12695.7 KFO95325.1 - 0.026 14.3 0.0 0.078 12.7 0.0 1.9 2 1 0 2 2 2 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 KFO95325.1 - 0.053 13.1 0.1 0.073 12.6 0.1 1.5 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase FSH1 PF03959.13 KFO95325.1 - 0.058 13.0 0.0 0.18 11.4 0.0 1.9 1 1 0 1 1 1 0 Serine hydrolase (FSH1) BTB PF00651.31 KFO95326.1 - 4.8e-44 149.1 2.2 8.7e-21 74.2 0.0 3.4 2 1 1 3 3 3 3 BTB/POZ domain Ank_2 PF12796.7 KFO95326.1 - 2.9e-10 40.6 0.0 3.2e-09 37.3 0.0 2.5 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFO95326.1 - 3.5e-10 39.9 0.1 6.7e-07 29.5 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFO95326.1 - 1.3e-08 35.2 0.1 7.6e-08 32.8 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFO95326.1 - 7.7e-08 32.0 0.1 0.00089 19.5 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat DUF3342 PF11822.8 KFO95326.1 - 6.2e-05 23.1 1.5 0.023 14.9 0.1 3.7 3 1 1 4 4 4 1 Domain of unknown function (DUF3342) Ank PF00023.30 KFO95326.1 - 0.00017 21.9 0.0 0.0043 17.4 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat BACK PF07707.15 KFO95326.1 - 0.00087 19.3 0.2 0.0026 17.8 0.2 1.9 1 0 0 1 1 1 1 BTB And C-terminal Kelch P4Ha_N PF08336.11 KFO95326.1 - 0.041 13.9 1.1 0.13 12.2 0.4 2.1 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region IFT20 PF14931.6 KFO95326.1 - 0.073 13.2 2.9 0.24 11.6 2.9 1.9 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 CD34_antigen PF06365.12 KFO95327.1 - 4.5e-80 268.2 0.0 6.1e-80 267.7 0.0 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family Shisa PF13908.6 KFO95327.1 - 0.04 14.2 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PMP1_2 PF08114.11 KFO95327.1 - 0.21 11.3 2.8 0.44 10.3 2.8 1.4 1 0 0 1 1 1 0 ATPase proteolipid family MCM PF00493.23 KFO95328.1 - 1.3e-98 328.6 0.0 2e-98 328.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFO95328.1 - 8.2e-37 125.9 0.1 1.7e-36 124.9 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFO95328.1 - 3.9e-29 100.9 1.7 9.6e-29 99.7 1.7 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFO95328.1 - 2.6e-17 63.3 0.7 1.1e-16 61.3 0.7 2.1 1 0 0 1 1 1 1 MCM N-terminal domain MCM2_N PF12619.8 KFO95328.1 - 2.5e-15 57.1 18.6 2.5e-15 57.1 18.6 2.2 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.21 KFO95328.1 - 1.3e-08 34.5 0.0 5.3e-07 29.2 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KFO95328.1 - 4.4e-07 29.8 0.0 3.1e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFO95328.1 - 7.5e-07 29.2 0.0 2.6e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 KFO95328.1 - 0.0011 18.7 0.4 0.004 17.0 0.1 2.1 2 0 0 2 2 1 1 AAA lid domain Sigma54_activat PF00158.26 KFO95328.1 - 0.003 17.3 0.1 1.2 8.8 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA PF00004.29 KFO95328.1 - 0.0033 17.9 0.0 0.0091 16.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 KFO95328.1 - 0.011 15.8 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.6 KFO95328.1 - 0.048 13.8 0.0 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Sema PF01403.19 KFO95329.1 - 6.2e-68 229.5 0.0 7.2e-68 229.3 0.0 1.0 1 0 0 1 1 1 1 Sema domain Plexin_cytopl PF08337.12 KFO95330.1 - 3.4e-262 871.1 5.7 4.1e-262 870.8 5.7 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.24 KFO95330.1 - 2.2e-46 155.8 12.7 5e-13 48.9 0.1 5.8 5 0 0 5 5 5 4 IPT/TIG domain TIG_2 PF18020.1 KFO95330.1 - 5.5e-32 110.3 0.1 2.3e-31 108.3 0.1 2.2 1 0 0 1 1 1 1 TIG domain found in plexin TIG_plexin PF17960.1 KFO95330.1 - 2.7e-27 94.6 5.7 2.8e-22 78.5 0.0 5.4 6 0 0 6 6 6 2 TIG domain PSI PF01437.25 KFO95330.1 - 2.2e-21 76.1 53.1 2.3e-09 37.7 12.4 3.7 3 0 0 3 3 3 3 Plexin repeat RasGAP PF00616.19 KFO95330.1 - 0.0012 18.6 1.2 0.0084 15.8 1.2 2.1 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase PSI_integrin PF17205.3 KFO95330.1 - 0.77 9.5 47.6 0.019 14.7 11.4 3.9 3 0 0 3 3 3 0 Integrin plexin domain Pyr_redox_2 PF07992.14 KFO95331.1 - 5.8e-53 180.0 0.1 7e-53 179.8 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFO95331.1 - 3.7e-28 98.0 0.0 9.4e-28 96.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFO95331.1 - 1.1e-16 61.1 2.7 1.5e-13 51.0 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFO95331.1 - 2.8e-13 49.8 0.9 4.1e-09 36.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFO95331.1 - 3.5e-07 29.7 0.1 1.8e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KFO95331.1 - 0.00027 20.3 0.2 0.15 11.3 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KFO95331.1 - 0.00074 18.3 0.4 0.0017 17.1 0.3 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KFO95331.1 - 0.0022 17.4 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFO95331.1 - 0.0041 16.4 1.1 0.012 14.9 0.1 2.0 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KFO95331.1 - 0.018 14.6 0.6 0.039 13.5 0.5 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 KFO95331.1 - 0.037 13.1 2.4 0.16 11.0 2.4 2.0 1 1 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KFO95331.1 - 0.15 12.3 7.3 0.094 13.0 0.9 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain XdhC_C PF13478.6 KFO95331.1 - 0.24 11.9 0.6 17 5.9 0.1 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain FAD_binding_3 PF01494.19 KFO95331.1 - 6.5 5.9 5.2 2.1 7.5 0.3 2.1 2 0 0 2 2 2 0 FAD binding domain Sulfotransfer_2 PF03567.14 KFO95332.1 - 1.9e-69 234.4 3.9 2.2e-69 234.2 3.9 1.0 1 0 0 1 1 1 1 Sulfotransferase family MgtE PF01769.16 KFO95333.1 - 1.5e-49 167.5 28.7 1.8e-28 99.4 4.0 3.2 4 0 0 4 4 4 2 Divalent cation transporter zf-C2H2 PF00096.26 KFO95334.1 - 6.4e-15 54.7 20.5 3.2e-05 24.1 1.6 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO95334.1 - 5.2e-13 48.8 20.0 4e-09 36.5 1.0 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFO95334.1 - 2.9e-08 33.9 26.3 0.00037 21.1 2.1 4.1 4 0 0 4 4 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFO95334.1 - 1.9e-05 25.2 8.2 0.19 12.4 0.2 3.7 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2_9 PF16293.5 KFO95334.1 - 0.011 15.6 0.9 0.068 13.0 0.1 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-met PF12874.7 KFO95334.1 - 0.013 15.9 4.4 0.18 12.3 0.8 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF2225 PF09986.9 KFO95334.1 - 0.039 13.7 0.4 0.12 12.1 0.4 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-Di19 PF05605.12 KFO95334.1 - 0.88 9.9 7.0 0.37 11.1 2.3 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 KFO95334.1 - 1.2 9.5 9.6 0.19 12.1 4.8 2.2 2 1 0 2 2 2 0 C2H2-type zinc ribbon IBR PF01485.21 KFO95334.1 - 1.4 9.2 6.7 4.4 7.6 5.1 2.5 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-C2HC_2 PF13913.6 KFO95334.1 - 1.5 8.8 4.4 0.51 10.3 0.5 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KFO95334.1 - 3.2 8.1 6.3 2.1 8.8 0.3 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KFO95335.1 - 1.2e-13 50.7 46.8 0.00065 20.0 0.4 7.4 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO95335.1 - 5.2e-11 42.4 45.1 0.011 16.5 0.6 7.2 7 0 0 7 7 7 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFO95335.1 - 2.9e-08 33.8 38.3 0.012 16.0 0.1 6.6 6 1 1 7 7 7 4 Zinc-finger double domain zf-C2H2_8 PF15909.5 KFO95335.1 - 6.1e-06 26.4 18.4 0.027 14.8 2.1 4.1 1 1 3 4 4 4 4 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KFO95335.1 - 7.4e-05 23.0 19.8 0.97 9.6 0.5 5.5 1 1 5 6 6 6 3 Aberrant zinc-finger FOXP-CC PF16159.5 KFO95335.1 - 0.0086 16.7 15.9 2.4 8.9 0.0 4.9 3 3 2 5 5 5 2 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KFO95335.1 - 2.4 8.3 26.5 2.2 8.4 1.9 5.9 6 0 0 6 6 6 0 C2H2-type zinc finger CHCH PF06747.13 KFO95336.1 - 1.3e-07 31.5 3.2 2.4e-07 30.7 3.2 1.4 1 0 0 1 1 1 1 CHCH domain TMEM43 PF07787.12 KFO95337.1 - 3e-87 292.2 0.0 4.5e-87 291.6 0.0 1.3 1 0 0 1 1 1 1 Transmembrane protein 43 DUF3325 PF11804.8 KFO95337.1 - 0.45 10.7 4.5 1.1 9.4 3.5 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3325) BHD_3 PF10405.9 KFO95338.1 - 2.1e-26 92.1 0.0 4.5e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 KFO95338.1 - 7.6e-21 74.3 5.1 7.6e-21 74.3 5.1 4.3 4 1 0 4 4 4 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 KFO95338.1 - 2.3e-17 62.5 0.0 6.2e-17 61.2 0.0 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KFO95338.1 - 4.7e-14 53.1 0.2 4.7e-14 53.1 0.2 4.4 4 1 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KFO95338.1 - 0.037 14.5 0.0 0.8 10.2 0.0 2.6 2 0 0 2 2 2 0 Transglutaminase-like superfamily PA26 PF04636.13 KFO95338.1 - 0.65 8.9 2.6 1.5 7.7 2.6 1.6 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) LSM PF01423.22 KFO95339.1 - 2.4e-20 72.0 0.2 3.1e-20 71.6 0.2 1.2 1 0 0 1 1 1 1 LSM domain vATP-synt_E PF01991.18 KFO95339.1 - 0.045 13.1 0.1 0.063 12.7 0.1 1.4 1 1 1 2 2 2 0 ATP synthase (E/31 kDa) subunit DUF150_C PF17384.2 KFO95339.1 - 0.064 13.4 0.2 0.11 12.7 0.2 1.5 1 1 0 1 1 1 0 RimP C-terminal SH3 domain Glutaredoxin PF00462.24 KFO95339.1 - 0.17 12.2 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin SNF PF00209.18 KFO95340.1 - 5.4e-236 784.3 37.5 6.3e-236 784.1 37.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family PDZ PF00595.24 KFO95341.1 - 4.1e-93 305.9 2.1 4.3e-13 49.4 0.1 7.2 7 0 0 7 7 7 7 PDZ domain PDZ_6 PF17820.1 KFO95341.1 - 2.2e-70 232.4 9.2 2e-12 46.8 0.1 7.3 7 0 0 7 7 7 7 PDZ domain PDZ_2 PF13180.6 KFO95341.1 - 3.1e-37 126.7 0.4 2.5e-05 24.5 0.0 7.4 7 0 0 7 7 7 7 PDZ domain Tricorn_PDZ PF14685.6 KFO95341.1 - 8.6e-11 41.7 1.1 0.13 12.3 0.0 6.7 7 0 0 7 7 7 2 Tricorn protease PDZ domain GRASP55_65 PF04495.14 KFO95341.1 - 0.00016 22.0 0.0 4.8 7.5 0.0 4.8 4 2 2 6 6 6 1 GRASP55/65 PDZ-like domain EutA PF06277.11 KFO95341.1 - 0.0069 15.3 0.3 0.053 12.4 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation protein EutA PDZ_4 PF17816.1 KFO95341.1 - 0.01 16.2 0.8 12 6.3 0.0 4.6 6 0 0 6 6 6 0 PDZ domain MoaE PF02391.17 KFO95341.1 - 0.18 12.1 0.2 21 5.4 0.0 3.1 3 0 0 3 3 3 0 MoaE protein DUF4078 PF13300.6 KFO95342.1 - 5.8e-27 93.8 10.5 5.8e-27 93.8 10.5 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4078) T2SSF PF00482.23 KFO95343.1 - 0.0043 17.0 1.2 0.19 11.7 0.0 2.7 2 1 0 3 3 3 1 Type II secretion system (T2SS), protein F CLZ PF16526.5 KFO95343.1 - 0.014 15.7 0.2 0.014 15.7 0.2 2.9 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Baculo_PEP_C PF04513.12 KFO95343.1 - 0.021 14.9 1.1 0.021 14.9 1.1 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus H-kinase_dim PF02895.14 KFO95343.1 - 0.045 14.1 2.9 4.5 7.7 0.7 3.0 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain FAP206 PF12018.8 KFO95343.1 - 0.074 12.5 6.3 1.4 8.4 1.3 2.4 1 1 1 2 2 2 0 Domain of unknown function Transcrip_act PF04949.13 KFO95343.1 - 0.45 10.4 8.7 0.27 11.1 4.9 2.2 2 1 0 2 2 2 0 Transcriptional activator FAM76 PF16046.5 KFO95343.1 - 0.92 8.8 7.4 1.4 8.2 7.4 1.3 1 0 0 1 1 1 0 FAM76 protein DUF2730 PF10805.8 KFO95343.1 - 1.3 9.1 4.5 1.5 8.9 0.2 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF2730) CorA PF01544.18 KFO95343.1 - 1.4 8.1 9.1 1.1 8.5 1.4 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Plexin_cytopl PF08337.12 KFO95344.1 - 1e-232 773.8 0.0 1.4e-232 773.3 0.0 1.2 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain Sema PF01403.19 KFO95344.1 - 2.6e-58 197.8 0.0 3.9e-58 197.3 0.0 1.2 1 0 0 1 1 1 1 Sema domain TIG PF01833.24 KFO95344.1 - 1.4e-32 111.6 1.8 1.6e-10 40.9 1.5 6.3 5 1 0 5 5 5 4 IPT/TIG domain TIG_2 PF18020.1 KFO95344.1 - 8.5e-25 87.2 0.9 7.7e-23 80.9 0.5 3.2 3 0 0 3 3 3 1 TIG domain found in plexin TIG_plexin PF17960.1 KFO95344.1 - 5.2e-20 71.2 2.7 4.9e-19 68.1 0.0 3.5 4 0 0 4 4 4 1 TIG domain PSI PF01437.25 KFO95344.1 - 3.4e-15 56.3 49.9 3.8e-08 33.7 15.0 3.6 3 0 0 3 3 3 3 Plexin repeat Pkinase PF00069.25 KFO95345.1 - 6.3e-39 133.9 0.0 1.9e-38 132.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO95345.1 - 7.5e-15 54.9 0.0 4.8e-14 52.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFO95345.1 - 0.0031 16.4 0.0 0.0043 15.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 KFO95345.1 - 0.019 14.0 0.1 0.029 13.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 KFO95345.1 - 0.16 11.6 0.0 0.35 10.4 0.0 1.5 2 0 0 2 2 2 0 RIO1 family SET PF00856.28 KFO95346.1 - 2.4e-07 31.3 6.2 2.4e-07 31.3 0.1 3.5 3 1 0 3 3 3 1 SET domain Myotub-related PF06602.14 KFO95347.1 - 0.00042 19.4 0.6 0.0012 17.8 0.6 1.5 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 KFO95347.1 - 0.0005 20.1 0.0 0.00086 19.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KFO95347.1 - 0.012 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Copine PF07002.16 KFO95348.1 - 5.1e-87 290.9 0.0 6.8e-87 290.5 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 KFO95348.1 - 2.5e-28 98.4 0.2 2.6e-13 50.2 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 KFO95348.1 - 7.7e-07 29.4 0.0 2e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 vWA found in TerF C terminus VCBS PF13517.6 KFO95348.1 - 0.012 16.2 0.4 0.049 14.2 0.4 2.1 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella zf-HC5HC2H_2 PF13832.6 KFO95349.1 - 2e-37 127.7 7.5 2e-37 127.7 7.5 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 KFO95349.1 - 1.6e-34 119.5 8.9 1.6e-34 119.5 8.9 3.3 3 1 0 3 3 3 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 KFO95349.1 - 8.4e-26 90.1 6.2 8.4e-26 90.1 6.2 3.2 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.25 KFO95349.1 - 1.6e-22 79.3 1.0 3.6e-22 78.2 1.0 1.6 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.17 KFO95349.1 - 1.9e-15 57.1 1.6 4.1e-15 56.0 0.0 2.5 2 0 0 2 2 2 1 PWWP domain PHD_2 PF13831.6 KFO95349.1 - 1e-14 53.8 3.2 1e-14 53.8 3.2 2.7 2 1 1 3 3 3 1 PHD-finger PHD PF00628.29 KFO95349.1 - 1.4e-08 34.5 27.0 3.4e-07 30.0 12.5 2.8 2 0 0 2 2 2 2 PHD-finger C1_2 PF03107.16 KFO95349.1 - 10 6.6 23.6 3.1 8.2 5.0 3.0 3 0 0 3 3 3 0 C1 domain Pkinase PF00069.25 KFO95350.1 - 9.7e-78 261.2 0.0 1.2e-77 260.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO95350.1 - 1.6e-36 126.0 0.0 2.1e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFO95350.1 - 3.8e-08 33.0 0.0 4.9e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFO95350.1 - 0.00051 18.9 0.0 0.0011 17.9 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFO95350.1 - 0.00063 19.2 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFO95350.1 - 0.0032 17.1 0.1 0.006 16.2 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KFO95350.1 - 0.026 14.4 0.0 0.099 12.6 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Tyrosinase PF00264.20 KFO95350.1 - 0.078 13.3 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Common central domain of tyrosinase YrbL-PhoP_reg PF10707.9 KFO95350.1 - 0.084 12.4 0.0 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Ada3 PF10198.9 KFO95351.1 - 1.1e-26 93.5 11.4 2.8e-26 92.2 11.4 1.7 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 ARPC4 PF05856.12 KFO95352.1 - 3.8e-53 179.5 5.6 4.1e-53 179.4 5.6 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Sm_like PF16243.5 KFO95352.1 - 0.0028 17.8 0.1 0.0048 17.0 0.1 1.5 1 0 0 1 1 1 1 Sm_like domain TTL PF03133.15 KFO95353.1 - 4.6e-72 242.6 0.0 2.2e-70 237.1 0.0 2.1 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KFO95353.1 - 0.077 12.2 0.0 1.5 8.0 0.0 2.3 2 1 0 2 2 2 0 YheC/D like ATP-grasp PseudoU_synth_2 PF00849.22 KFO95354.1 - 1.6e-06 28.3 0.0 2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase Homeobox_KN PF05920.11 KFO95354.1 - 0.23 11.4 0.7 0.79 9.7 0.1 2.1 2 0 0 2 2 2 0 Homeobox KN domain Jagunal PF07086.12 KFO95355.1 - 4e-66 222.7 4.6 4.5e-66 222.5 4.6 1.0 1 0 0 1 1 1 1 Jagunal, ER re-organisation during oogenesis DUF3810 PF12725.7 KFO95355.1 - 0.13 11.6 2.1 0.17 11.2 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) IHO1 PF15771.5 KFO95357.1 - 7.8e-22 77.8 4.2 9e-22 77.6 4.2 1.1 1 0 0 1 1 1 1 Interactor of HORMAD1 protein 1 Kelch_1 PF01344.25 KFO95358.1 - 5.8e-48 160.2 0.0 9.7e-09 34.7 0.0 7.8 8 0 0 8 8 8 6 Kelch motif Kelch_6 PF13964.6 KFO95358.1 - 1.4e-33 114.0 3.1 2.6e-05 24.3 0.0 7.4 3 3 4 7 7 7 7 Kelch motif Kelch_3 PF13415.6 KFO95358.1 - 1.9e-30 104.5 0.7 1e-06 28.9 0.1 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KFO95358.1 - 3.5e-27 94.1 0.4 4.4e-06 26.6 0.1 7.2 6 1 1 7 7 7 6 Galactose oxidase, central domain Kelch_2 PF07646.15 KFO95358.1 - 3.8e-19 67.8 0.4 0.0034 17.3 0.0 7.8 7 1 0 7 7 7 5 Kelch motif Kelch_5 PF13854.6 KFO95358.1 - 3.4e-09 36.5 0.2 0.0098 15.9 0.0 5.6 6 0 0 6 6 6 2 Kelch motif DUF1668 PF07893.13 KFO95358.1 - 0.12 11.7 3.2 0.087 12.2 0.4 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1668) CCDC71L PF15374.6 KFO95360.1 - 5.6e-160 532.9 14.8 6.3e-160 532.7 14.8 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 71L SNF PF00209.18 KFO95361.1 - 1.6e-186 621.0 27.4 1.9e-186 620.8 27.4 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family tRNA-synt_1c PF00749.21 KFO95362.1 - 9.8e-114 379.5 0.0 1.3e-113 379.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KFO95362.1 - 5.7e-49 166.3 0.0 1.2e-48 165.3 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.15 KFO95362.1 - 5.4e-36 124.1 0.0 1.2e-35 122.9 0.0 1.6 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.15 KFO95362.1 - 7e-27 94.2 1.9 1.2e-26 93.4 1.9 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DUF3504 PF12012.8 KFO95363.1 - 1e-62 210.8 1.4 1e-62 210.8 1.4 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF3504) CARD PF00619.21 KFO95363.1 - 0.0019 18.2 0.0 0.0052 16.8 0.0 1.7 1 0 0 1 1 1 1 Caspase recruitment domain PCNA_C PF02747.15 KFO95363.1 - 0.068 13.3 0.8 0.17 12.0 0.8 1.6 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, C-terminal domain IMPDH PF00478.25 KFO95364.1 - 4.3e-129 430.4 3.6 4.9e-129 430.3 3.6 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KFO95364.1 - 6e-14 52.2 1.0 1.8e-08 34.2 0.4 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase CBS PF00571.28 KFO95364.1 - 2.3e-13 50.3 0.9 3.7e-05 24.1 0.0 2.8 3 0 0 3 3 3 2 CBS domain FMN_dh PF01070.18 KFO95364.1 - 1.8e-10 40.4 0.5 2.7e-10 39.8 0.5 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 KFO95364.1 - 8.6e-07 28.6 1.1 0.00034 20.2 0.1 2.3 1 1 1 2 2 2 2 Histidine biosynthesis protein NanE PF04131.14 KFO95364.1 - 3.4e-06 26.4 0.2 7.5e-06 25.3 0.2 1.6 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.14 KFO95364.1 - 0.00053 19.4 2.4 0.0012 18.2 1.6 1.9 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 KFO95364.1 - 0.0016 17.7 0.9 0.0028 16.8 0.9 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Dus PF01207.17 KFO95364.1 - 0.0025 17.0 0.8 0.37 9.8 0.0 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) Aldolase PF01081.19 KFO95364.1 - 0.011 15.2 0.6 0.91 8.9 0.1 2.8 3 0 0 3 3 3 0 KDPG and KHG aldolase G3P_antiterm PF04309.12 KFO95364.1 - 0.016 14.6 0.5 0.69 9.3 0.1 2.5 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator DUF561 PF04481.12 KFO95364.1 - 0.049 12.8 0.3 0.098 11.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF561) B12-binding PF02310.19 KFO95364.1 - 0.099 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain DHO_dh PF01180.21 KFO95364.1 - 0.26 10.5 3.7 0.14 11.4 0.3 2.0 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase DUF498 PF04430.14 KFO95365.1 - 9.4e-27 93.2 0.0 1e-26 93.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) GCSF PF16647.5 KFO95365.1 - 0.15 11.9 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Granulocyte colony-stimulating factor DALR_1 PF05746.15 KFO95366.1 - 2.9e-20 72.6 0.0 5.1e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 DALR anticodon binding domain WD40 PF00400.32 KFO95367.1 - 1.1e-09 38.7 11.7 0.34 11.8 0.2 8.9 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO95367.1 - 0.0001 22.5 0.0 0.14 12.4 0.0 3.8 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nsp3_PL2pro PF12124.8 KFO95367.1 - 0.0036 17.1 0.0 0.015 15.0 0.0 2.0 2 0 0 2 2 2 1 Coronavirus polyprotein cleavage domain 2OG-FeII_Oxy_3 PF13640.6 KFO95368.1 - 1.2e-14 54.9 0.1 3.1e-14 53.6 0.1 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily EF-hand_7 PF13499.6 KFO95368.1 - 7.2e-09 36.0 0.0 2.7e-08 34.1 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFO95368.1 - 7.7e-08 31.4 0.0 0.0048 16.4 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFO95368.1 - 1.9e-06 27.4 1.2 0.018 14.9 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KFO95368.1 - 2.2e-05 23.7 0.1 0.17 11.5 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFO95368.1 - 0.0002 21.1 0.0 0.11 12.3 0.0 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KFO95368.1 - 0.083 13.2 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain TruB_C PF09142.11 KFO95368.1 - 0.2 11.5 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal Fz PF01392.22 KFO95369.1 - 7.4e-28 97.4 5.1 7.4e-28 97.4 5.1 1.7 2 0 0 2 2 2 1 Fz domain IBR PF01485.21 KFO95370.1 - 8.5e-21 74.0 45.5 4.1e-13 49.3 6.6 3.8 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KFO95370.1 - 0.0012 18.6 6.2 0.0012 18.6 6.2 4.1 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFO95370.1 - 0.0018 18.1 9.8 0.0018 18.1 9.8 4.4 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFO95370.1 - 0.011 16.1 47.0 0.037 14.4 9.9 4.1 2 1 1 3 3 3 0 Ring finger domain zf-RING_UBOX PF13445.6 KFO95370.1 - 0.022 14.8 3.2 0.022 14.8 3.2 3.6 3 0 0 3 3 3 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFO95370.1 - 0.026 14.7 4.9 0.026 14.7 4.9 4.5 4 1 0 4 4 4 0 zinc finger of C3HC4-type, RING Mito_carr PF00153.27 KFO95371.1 - 3.5e-57 190.3 0.9 1.5e-21 76.1 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein cNMP_binding PF00027.29 KFO95372.1 - 5.2e-41 138.6 0.1 1.1e-21 76.7 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain ComC PF03047.14 KFO95373.1 - 0.02 14.7 0.3 0.032 14.0 0.3 1.3 1 0 0 1 1 1 0 COMC family RNase_P_Rpp14 PF01900.19 KFO95374.1 - 9.3e-07 29.0 0.0 1.1e-06 28.9 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family MaoC_dehydratas PF01575.19 KFO95375.1 - 7.8e-20 70.7 0.0 1e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KFO95375.1 - 2.5e-06 27.6 0.0 5.2e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.22 KFO95375.1 - 0.004 17.5 0.0 0.0092 16.3 0.0 1.7 1 1 0 1 1 1 1 Thioesterase superfamily PX PF00787.24 KFO95376.1 - 3.1e-17 62.6 0.1 4.4e-16 58.9 0.0 2.9 2 0 0 2 2 2 1 PX domain Pkinase PF00069.25 KFO95376.1 - 4.6e-10 39.3 0.2 9.3e-09 35.0 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO95376.1 - 1.1e-08 34.7 0.0 8.3e-07 28.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase WH2 PF02205.20 KFO95376.1 - 9.4e-08 31.7 0.0 1.8e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 WH2 motif Rrn6 PF10214.9 KFO95376.1 - 0.75 8.2 9.5 1 7.7 9.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Transket_pyr PF02779.24 KFO95377.1 - 7.7e-44 149.5 0.0 1.6e-43 148.5 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFO95377.1 - 2.8e-34 117.7 0.2 2.9e-33 114.4 0.2 2.2 1 1 0 1 1 1 1 Transketolase, C-terminal domain BTB_2 PF02214.22 KFO95378.1 - 7.8e-22 77.4 0.1 2e-21 76.1 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 KFO95378.1 - 0.00038 20.5 0.0 0.00067 19.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain ACOX PF01756.19 KFO95379.1 - 1.4e-64 217.0 1.6 2.2e-63 213.1 0.4 2.3 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KFO95379.1 - 1.1e-27 97.0 0.1 2.2e-27 96.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KFO95379.1 - 1.8e-07 31.2 0.0 1e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KFO95379.1 - 1.3e-05 25.4 0.0 3.2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MamL-1 PF09596.10 KFO95379.1 - 0.18 12.1 0.4 0.75 10.1 0.4 2.1 1 0 0 1 1 1 0 MamL-1 domain DUF1151 PF06625.11 KFO95380.1 - 1.9e-36 124.5 14.3 2e-36 124.4 14.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1151) ILEI PF15711.5 KFO95381.1 - 2.3e-27 95.3 0.1 3.6e-27 94.7 0.1 1.3 1 0 0 1 1 1 1 Interleukin-like EMT inducer HIT PF01230.23 KFO95382.1 - 7e-18 65.2 0.0 7.7e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KFO95382.1 - 0.00034 21.1 0.0 0.00041 20.8 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding RVT_1 PF00078.27 KFO95383.1 - 0.094 12.2 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4570 PF15134.6 KFO95384.1 - 1.4e-46 157.0 4.3 1.6e-46 156.8 4.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4570) Angiomotin_C PF12240.8 KFO95384.1 - 0.013 15.0 1.9 0.018 14.6 1.9 1.2 1 0 0 1 1 1 0 Angiomotin C terminal Mis12 PF05859.12 KFO95384.1 - 0.04 14.0 1.0 0.58 10.2 1.0 2.2 1 1 0 1 1 1 0 Mis12 protein AMPKBI PF04739.15 KFO95384.1 - 0.14 12.4 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interaction domain zf-H2C2_2 PF13465.6 KFO95385.1 - 5.1e-21 74.1 28.0 2.2e-06 27.9 4.1 4.1 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFO95385.1 - 5.8e-20 70.6 28.4 5.7e-07 29.6 2.1 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO95385.1 - 3e-15 55.6 25.9 0.00036 21.1 0.8 4.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFO95385.1 - 2.4e-07 30.6 24.7 0.0023 17.9 1.1 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO95385.1 - 7.2e-07 29.3 24.8 0.084 13.2 1.4 4.6 3 1 1 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFO95385.1 - 0.00012 22.3 13.8 0.0083 16.4 3.3 2.2 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding C1_1 PF00130.22 KFO95385.1 - 0.00084 19.2 19.5 0.0019 18.0 5.6 3.2 2 1 1 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.10 KFO95385.1 - 0.00089 19.3 14.3 0.18 11.9 3.5 3.5 3 1 0 3 3 3 1 Zinc ribbon domain XPA_N PF01286.18 KFO95385.1 - 0.0053 16.8 11.0 1.2 9.2 0.1 4.2 4 0 0 4 4 4 1 XPA protein N-terminal zf-Sec23_Sec24 PF04810.15 KFO95385.1 - 0.0064 16.5 14.4 0.081 13.0 3.4 4.0 3 1 1 4 4 4 1 Sec23/Sec24 zinc finger ADK_lid PF05191.14 KFO95385.1 - 0.016 15.2 12.1 0.14 12.2 0.4 3.1 2 2 1 3 3 3 0 Adenylate kinase, active site lid Prok-RING_1 PF14446.6 KFO95385.1 - 0.019 14.9 12.6 4.2 7.4 0.2 4.2 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 BolA PF01722.18 KFO95385.1 - 0.022 15.0 1.0 4 7.8 0.4 2.6 1 1 1 2 2 2 0 BolA-like protein Zf_RING PF16744.5 KFO95385.1 - 0.033 14.3 14.0 0.077 13.1 0.4 3.8 1 1 3 4 4 4 0 KIAA1045 RING finger zf-met PF12874.7 KFO95385.1 - 0.04 14.3 21.9 7.2 7.1 0.6 4.5 3 1 0 4 4 4 0 Zinc-finger of C2H2 type FYDLN_acid PF09538.10 KFO95385.1 - 0.05 14.3 2.6 36 5.1 0.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) Rep_fac-A_C PF08646.10 KFO95385.1 - 0.066 13.0 10.4 0.71 9.6 1.5 2.4 1 1 2 3 3 3 0 Replication factor-A C terminal domain zf-C2H2_3rep PF18868.1 KFO95385.1 - 0.077 13.7 12.2 11 6.7 8.6 3.4 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-MYST PF17772.1 KFO95385.1 - 0.097 12.3 9.2 0.48 10.1 0.1 3.3 4 0 0 4 4 4 0 MYST family zinc finger domain zf-C2H2_11 PF16622.5 KFO95385.1 - 0.1 12.4 0.3 0.1 12.4 0.3 3.3 4 0 0 4 4 3 0 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 KFO95385.1 - 0.19 12.5 13.5 70 4.3 13.5 2.3 1 1 0 1 1 1 0 zinc-ribbon family zf-trcl PF13451.6 KFO95385.1 - 0.22 11.4 14.0 5.9 6.9 0.2 4.2 4 1 0 4 4 4 0 Probable zinc-ribbon domain zf_UBZ PF18439.1 KFO95385.1 - 0.27 10.9 14.3 9.3 5.9 0.4 4.4 3 1 2 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-C2H2_9 PF16293.5 KFO95385.1 - 0.3 11.0 3.4 27 4.7 0.1 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) Cript PF10235.9 KFO95385.1 - 0.35 11.5 17.9 23 5.6 1.0 3.5 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT zinc-ribbons_6 PF07191.12 KFO95385.1 - 0.44 10.6 15.1 6.2 6.9 3.3 3.5 1 1 1 2 2 2 0 zinc-ribbons zf_C2H2_13 PF18508.1 KFO95385.1 - 0.62 9.7 11.1 3.3 7.4 0.2 3.7 4 0 0 4 4 4 0 Zinc finger domain HypA PF01155.19 KFO95385.1 - 0.69 10.0 11.2 3.5 7.7 4.7 2.6 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-HIT PF04438.16 KFO95385.1 - 0.71 9.8 15.6 7.5 6.5 0.3 4.2 4 0 0 4 4 4 0 HIT zinc finger zf-CHCC PF10276.9 KFO95385.1 - 0.82 9.8 9.3 8.6 6.5 0.0 3.8 4 0 0 4 4 4 0 Zinc-finger domain zf-AN1 PF01428.16 KFO95385.1 - 1.3 9.3 21.2 3.1 8.0 0.8 4.2 3 1 1 4 4 4 0 AN1-like Zinc finger zf-LYAR PF08790.11 KFO95385.1 - 1.5 8.8 17.2 2.5 8.1 0.9 4.1 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-BED PF02892.15 KFO95385.1 - 2 8.5 25.6 0.15 12.1 2.4 4.1 1 1 3 4 4 4 0 BED zinc finger zinc_ribbon_9 PF14369.6 KFO95385.1 - 2.1 8.7 12.7 11 6.4 0.5 4.0 4 0 0 4 4 4 0 zinc-ribbon zf-nanos PF05741.13 KFO95385.1 - 2.6 8.4 17.0 3.8 7.8 5.4 3.7 3 1 0 3 3 3 0 Nanos RNA binding domain FYVE PF01363.21 KFO95385.1 - 2.7 8.2 20.2 7.9e+02 0.3 20.0 3.2 1 1 0 1 1 1 0 FYVE zinc finger C5HCH PF17982.1 KFO95385.1 - 3.6 7.8 15.1 4.2 7.6 0.5 3.9 3 1 1 4 4 4 0 NSD Cys-His rich domain zf-CCHC_2 PF13696.6 KFO95385.1 - 3.8 7.4 18.9 0.77 9.6 1.1 4.2 4 0 0 4 4 4 0 Zinc knuckle DUF3268 PF11672.8 KFO95385.1 - 4.2 7.7 11.5 0.91 9.9 2.3 2.2 1 1 1 2 2 2 0 zinc-finger-containing domain zf-C2H2_2 PF12756.7 KFO95385.1 - 4.2 7.8 18.4 17 5.8 2.9 3.9 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) TF_Zn_Ribbon PF08271.12 KFO95385.1 - 6.3 6.4 12.7 19 4.9 0.3 3.8 4 0 0 4 4 4 0 TFIIB zinc-binding zf-C2HE PF16278.5 KFO95385.1 - 6.4 7.3 20.1 0.5 10.9 2.3 3.9 2 2 2 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 KFO95385.1 - 7.5 6.6 19.7 12 6.0 0.2 4.4 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Ribosomal_L37ae PF01780.19 KFO95385.1 - 7.6 6.7 16.2 12 6.1 4.2 3.6 1 1 2 3 3 3 0 Ribosomal L37ae protein family PHD PF00628.29 KFO95385.1 - 9 6.3 18.2 0.23 11.4 3.2 3.4 2 2 0 2 2 2 0 PHD-finger Desulfoferrod_N PF06397.12 KFO95385.1 - 9 6.0 15.9 8.8 6.1 0.3 4.2 4 0 0 4 4 4 0 Desulfoferrodoxin, N-terminal domain MARVEL PF01284.23 KFO95386.1 - 1.1e-36 126.1 6.0 1.4e-36 125.7 6.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.12 KFO95386.1 - 0.0062 16.3 1.5 0.0089 15.8 1.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF588) DUF1129 PF06570.11 KFO95386.1 - 0.12 11.9 0.2 0.18 11.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF3278 PF11683.8 KFO95386.1 - 0.19 11.8 1.6 0.38 10.8 1.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3278) Frizzled PF01534.17 KFO95386.1 - 0.88 8.6 7.7 0.35 9.8 1.9 2.2 1 1 0 2 2 2 0 Frizzled/Smoothened family membrane region S_100 PF01023.19 KFO95387.1 - 3.5e-05 23.4 0.0 5.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_8 PF13833.6 KFO95387.1 - 0.002 17.9 0.0 0.05 13.5 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 KFO95387.1 - 0.013 15.9 0.1 0.024 15.1 0.1 1.3 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 KFO95387.1 - 0.074 13.0 0.1 1.7 8.8 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain THOC7 PF05615.13 KFO95388.1 - 6.5e-40 136.5 9.6 8.7e-40 136.1 0.8 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 UPF0193 PF05250.11 KFO95388.1 - 0.0011 18.9 5.2 0.0011 18.9 5.2 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0193) COG2 PF06148.11 KFO95388.1 - 0.22 11.6 10.9 0.062 13.4 1.3 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 KFO95388.1 - 0.32 9.8 18.8 0.07 12.0 3.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein NPV_P10 PF05531.12 KFO95388.1 - 0.56 10.7 3.0 6.9 7.2 2.4 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 KFO95388.1 - 2.3 7.5 9.4 0.075 12.4 1.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF16 PF01519.16 KFO95388.1 - 2.5 8.6 13.7 0.17 12.4 2.6 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 V_ATPase_I PF01496.19 KFO95388.1 - 2.6 5.9 12.2 3.2 5.6 12.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AATF-Che1 PF13339.6 KFO95388.1 - 3.5 8.3 13.7 2.2 9.0 6.3 2.2 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor EP400_N PF15790.5 KFO95388.1 - 3.7 6.3 7.3 4.7 5.9 7.3 1.2 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal DUF1664 PF07889.12 KFO95388.1 - 4.2 7.4 9.0 17 5.5 3.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Med9 PF07544.13 KFO95388.1 - 4.3 7.5 18.8 0.94 9.6 3.0 3.2 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 SCA7 PF08313.12 KFO95389.1 - 5.4e-26 90.3 1.9 5.4e-26 90.3 1.9 2.4 2 1 0 2 2 2 1 SCA7, zinc-binding domain OrsD PF12013.8 KFO95389.1 - 0.15 12.6 0.1 0.15 12.6 0.1 2.8 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D RPN7 PF10602.9 KFO95390.1 - 4.4e-63 212.1 2.7 6.5e-63 211.6 2.7 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KFO95390.1 - 2e-18 66.8 0.3 5.4e-18 65.4 0.1 1.9 2 0 0 2 2 2 1 PCI domain RPW8 PF05659.11 KFO95390.1 - 0.024 14.3 2.5 1.9 8.2 0.3 3.2 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF1732 PF08340.11 KFO95390.1 - 0.042 13.8 1.9 5.2 7.1 0.6 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF1732) LigB PF02900.18 KFO95390.1 - 0.33 10.0 0.7 0.71 8.9 0.5 1.6 1 1 1 2 2 2 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase TSP_1 PF00090.19 KFO95391.1 - 2.1e-07 31.1 19.5 0.00024 21.3 1.9 2.1 2 0 0 2 2 2 2 Thrombospondin type 1 domain rve PF00665.26 KFO95392.1 - 4e-24 85.1 0.2 6.3e-24 84.5 0.2 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_Zn PF02022.19 KFO95392.1 - 4.8e-12 45.6 0.5 1e-11 44.6 0.5 1.6 1 0 0 1 1 1 1 Integrase Zinc binding domain RNase_H PF00075.24 KFO95392.1 - 3.2e-05 24.2 0.0 8.4e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 RNase H UCR_UQCRX_QCR9 PF05365.12 KFO95392.1 - 0.0034 17.3 0.1 0.007 16.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like rve_3 PF13683.6 KFO95392.1 - 0.048 13.5 0.1 0.26 11.1 0.0 2.3 3 0 0 3 3 3 0 Integrase core domain 7tm_2 PF00002.24 KFO95397.1 - 6.3e-62 209.0 17.5 9e-62 208.5 17.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) TSP_1 PF00090.19 KFO95397.1 - 1.4e-48 162.9 94.9 1.4e-13 50.9 7.2 6.9 7 0 0 7 7 7 5 Thrombospondin type 1 domain GAIN PF16489.5 KFO95397.1 - 9.5e-40 136.3 0.3 2.1e-39 135.1 0.3 1.6 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Fox-1_C PF12414.8 KFO95400.1 - 5.7e-26 90.7 6.6 5.7e-26 90.7 6.6 2.6 3 0 0 3 3 3 1 Calcitonin gene-related peptide regulator C terminal RRM_1 PF00076.22 KFO95400.1 - 1.4e-18 66.5 0.1 2.2e-18 65.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFO95400.1 - 0.037 13.6 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Globin PF00042.22 KFO95401.1 - 2.6e-23 82.7 0.2 4.6e-23 81.9 0.2 1.4 1 0 0 1 1 1 1 Globin TPR_8 PF13181.6 KFO95401.1 - 0.021 15.0 0.3 2.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat AbiJ_NTD5 PF18865.1 KFO95401.1 - 0.056 13.3 0.0 0.21 11.4 0.0 1.9 1 1 1 2 2 2 0 AbiJ N-terminal domain 5 Ras PF00071.22 KFO95402.1 - 4.3e-40 136.9 0.0 6.6e-40 136.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO95402.1 - 4.3e-14 52.8 0.0 7.2e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO95402.1 - 5.2e-08 32.5 0.0 7.2e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFO95402.1 - 0.0016 18.5 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFO95402.1 - 0.0038 16.8 0.0 0.013 15.1 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFO95402.1 - 0.026 13.9 0.0 0.14 11.6 0.0 1.9 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KFO95402.1 - 0.052 13.0 0.1 0.37 10.2 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein AAA_16 PF13191.6 KFO95402.1 - 0.12 12.8 0.0 0.19 12.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KFO95402.1 - 0.13 12.1 0.1 2.4 8.1 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase MCM PF00493.23 KFO95403.1 - 3.9e-100 333.6 0.0 7.4e-100 332.6 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFO95403.1 - 2.3e-40 137.3 0.7 4.6e-40 136.4 0.7 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFO95403.1 - 1.9e-26 92.3 1.3 5.3e-26 90.9 0.8 2.2 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 KFO95403.1 - 5.5e-18 65.5 1.3 1.4e-17 64.2 1.3 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFO95403.1 - 1.2e-06 28.1 0.0 0.00048 19.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFO95403.1 - 0.0004 20.4 0.0 0.0014 18.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFO95403.1 - 0.009 15.9 0.0 0.034 14.0 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TrmB PF01978.19 KFO95403.1 - 0.027 14.4 1.3 0.56 10.1 0.4 2.5 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Sigma54_activat PF00158.26 KFO95403.1 - 0.034 13.9 0.0 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Heme_oxygenase PF01126.20 KFO95404.1 - 1e-78 263.9 2.1 1.4e-78 263.4 2.1 1.1 1 0 0 1 1 1 1 Heme oxygenase PYC_OADA PF02436.18 KFO95404.1 - 0.11 12.2 0.5 0.23 11.2 0.1 1.8 2 0 0 2 2 2 0 Conserved carboxylase domain VHS PF00790.19 KFO95405.1 - 3.8e-45 153.2 0.0 6.7e-45 152.4 0.0 1.4 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KFO95405.1 - 4.4e-24 84.6 3.7 9.5e-24 83.5 3.7 1.5 1 0 0 1 1 1 1 GAT domain Homeodomain PF00046.29 KFO95406.1 - 4.5e-24 84.1 4.3 6.2e-24 83.6 4.3 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO95406.1 - 0.00094 19.0 0.9 0.0016 18.3 0.1 1.8 2 0 0 2 2 2 1 Homeobox KN domain Glyco_transf_49 PF13896.6 KFO95407.1 - 6.9e-58 196.6 4.0 4.9e-45 154.3 1.5 2.3 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_transf_8 PF01501.20 KFO95407.1 - 8.9e-19 68.0 0.6 1.5e-18 67.2 0.6 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KFO95407.1 - 6.7e-07 29.0 3.6 1.1e-06 28.3 3.6 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Mto2_bdg PF12808.7 KFO95407.1 - 1.5 9.2 6.4 0.31 11.4 2.4 1.9 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Synapsin_C PF02750.14 KFO95408.1 - 1.5e-131 436.1 0.4 1.9e-131 435.7 0.4 1.1 1 0 0 1 1 1 1 Synapsin, ATP binding domain Synapsin PF02078.16 KFO95408.1 - 1e-35 122.0 0.2 1.2e-34 118.6 0.0 2.5 3 0 0 3 3 3 1 Synapsin, N-terminal domain RimK PF08443.11 KFO95408.1 - 9.8e-05 22.0 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain TIMP PF00965.17 KFO95409.1 - 2.1e-64 216.7 8.3 2.5e-64 216.4 8.3 1.1 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase F-box-like PF12937.7 KFO95410.1 - 9.8e-11 41.4 2.8 1.9e-10 40.5 2.8 1.5 1 0 0 1 1 1 1 F-box-like PI31_Prot_N PF11566.8 KFO95410.1 - 1.6e-05 24.8 0.0 4.9e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 PI31 proteasome regulator N-terminal F-box PF00646.33 KFO95410.1 - 2.6e-05 24.0 1.4 4.8e-05 23.1 1.4 1.5 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 KFO95410.1 - 0.012 16.2 0.4 0.012 16.2 0.4 1.5 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box_4 PF15966.5 KFO95410.1 - 0.045 13.6 0.1 0.076 12.9 0.1 1.3 1 0 0 1 1 1 0 F-box DUF1180 PF06679.12 KFO95410.1 - 0.23 11.9 0.4 0.4 11.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) HLH PF00010.26 KFO95411.1 - 8.6e-18 64.0 2.2 1.4e-17 63.4 2.2 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain zf_PR_Knuckle PF18445.1 KFO95412.1 - 8.9e-29 99.0 13.5 6.7e-28 96.2 3.8 4.0 3 0 0 3 3 3 2 PR zinc knuckle motif zf-H2C2_2 PF13465.6 KFO95412.1 - 4.3e-26 90.1 54.9 1.3e-07 31.7 0.7 8.4 8 1 0 8 8 8 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFO95412.1 - 3.8e-20 71.1 63.1 1.3e-05 25.4 1.8 8.5 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO95412.1 - 2.8e-17 61.9 62.9 0.00094 19.8 1.6 8.6 8 0 0 8 8 8 7 C2H2-type zinc finger zf-met PF12874.7 KFO95412.1 - 5.4e-05 23.4 42.7 0.00085 19.6 1.1 7.6 7 0 0 7 7 7 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFO95412.1 - 9.6e-05 22.6 49.9 0.027 14.7 0.2 8.1 7 1 1 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFO95412.1 - 0.0033 17.2 1.2 0.0033 17.2 1.2 6.3 6 1 0 6 6 6 3 C2H2-type zinc-finger domain Mu-like_Com PF10122.9 KFO95412.1 - 0.097 12.1 5.5 0.075 12.5 2.9 2.2 2 1 0 2 2 2 0 Mu-like prophage protein Com zf-C2H2_2 PF12756.7 KFO95412.1 - 1.3 9.4 36.5 5.8 7.3 9.7 5.9 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) WD40 PF00400.32 KFO95413.1 - 1e-12 48.3 1.7 0.0021 18.9 0.1 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO95413.1 - 0.00044 20.5 0.1 0.067 13.5 0.1 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain BTB PF00651.31 KFO95414.1 - 9e-24 83.8 0.5 5.3e-22 78.1 0.2 3.3 2 1 1 3 3 3 1 BTB/POZ domain Ank_2 PF12796.7 KFO95414.1 - 4.9e-20 71.9 0.0 1.3e-09 38.5 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFO95414.1 - 7.8e-19 65.8 0.1 1.7e-05 24.8 0.0 5.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KFO95414.1 - 5.2e-17 62.0 0.0 0.00038 20.9 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFO95414.1 - 1.2e-15 57.1 0.3 1.2e-06 28.7 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KFO95414.1 - 1.2e-14 54.1 0.1 0.0072 16.6 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeats (many copies) BACK PF07707.15 KFO95414.1 - 0.0016 18.5 0.8 0.0064 16.6 0.0 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch DUF3342 PF11822.8 KFO95414.1 - 0.14 12.4 0.0 6.6 7.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) FAD_binding_7 PF03441.14 KFO95415.1 - 3.8e-80 268.1 0.4 6.4e-80 267.4 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KFO95415.1 - 3e-25 89.1 0.0 6.1e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase mTERF PF02536.14 KFO95416.1 - 5.6e-27 94.5 7.1 7.6e-27 94.1 7.0 1.3 1 1 0 1 1 1 1 mTERF RRF_GI PF12614.8 KFO95416.1 - 0.0049 17.0 0.3 0.022 14.9 0.3 2.1 1 0 0 1 1 1 1 Ribosome recycling factor K-box PF01486.17 KFO95416.1 - 0.021 15.0 0.1 4.6 7.5 0.0 3.2 3 0 0 3 3 3 0 K-box region DUF4332 PF14229.6 KFO95416.1 - 0.095 12.9 0.5 0.23 11.7 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) UPF0444 PF15475.6 KFO95417.1 - 9.7e-46 154.0 14.1 1.1e-45 153.8 14.1 1.0 1 0 0 1 1 1 1 Transmembrane protein C12orf23, UPF0444 Ric8 PF10165.9 KFO95418.1 - 6.6e-131 437.5 3.3 7.6e-131 437.3 3.3 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Rif1_N PF12231.8 KFO95418.1 - 0.0025 16.8 0.3 0.0053 15.8 0.3 1.5 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal RFX_DNA_binding PF02257.15 KFO95419.1 - 1.4e-34 118.5 0.0 4.3e-34 117.0 0.0 1.9 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 KFO95419.1 - 5.8e-05 23.5 0.0 0.00016 22.1 0.0 1.7 1 0 0 1 1 1 1 Poxvirus D5 protein-like RNA_pol_Rpb2_6 PF00562.28 KFO95420.1 - 2e-128 428.8 0.0 6.3e-128 427.2 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KFO95420.1 - 1.2e-54 184.9 0.6 2e-54 184.2 0.6 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KFO95420.1 - 5.8e-35 119.6 0.7 1.7e-34 118.1 0.2 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KFO95420.1 - 6.5e-28 97.7 1.5 7.8e-28 97.4 0.5 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KFO95420.1 - 5.3e-27 93.9 1.1 1.4e-26 92.5 1.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KFO95420.1 - 3.6e-21 75.1 0.0 9e-21 73.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KFO95420.1 - 5.3e-10 39.7 5.5 6.4e-10 39.4 3.1 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 5 Tcp11 PF05794.13 KFO95421.1 - 4e-113 378.8 0.2 4e-113 378.8 0.2 1.3 2 0 0 2 2 2 1 T-complex protein 11 RAP1 PF07218.11 KFO95421.1 - 1 7.6 5.9 0.63 8.3 3.0 1.8 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Fib_alpha PF08702.10 KFO95422.1 - 3.3e-06 27.3 46.6 0.0052 17.0 4.6 5.2 1 1 5 6 6 6 3 Fibrinogen alpha/beta chain family Spc7 PF08317.11 KFO95422.1 - 2e-05 23.6 52.2 0.0071 15.3 7.1 4.5 1 1 3 5 5 5 5 Spc7 kinetochore protein Tropomyosin PF00261.20 KFO95422.1 - 4.1e-05 23.1 45.0 0.0048 16.3 10.8 4.6 1 1 2 4 4 4 3 Tropomyosin Baculo_PEP_C PF04513.12 KFO95422.1 - 6.3e-05 23.0 33.4 0.024 14.7 7.0 5.1 1 1 3 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.12 KFO95422.1 - 0.00046 20.2 43.7 0.0031 17.6 4.2 4.9 2 2 1 4 4 4 1 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.7 KFO95422.1 - 0.00093 19.4 13.5 0.00093 19.4 13.5 5.0 1 1 3 5 5 5 1 Tropomyosin like GAS PF13851.6 KFO95422.1 - 0.0013 18.1 48.1 0.014 14.7 13.5 4.6 1 1 3 4 4 4 3 Growth-arrest specific micro-tubule binding Syntaxin-6_N PF09177.11 KFO95422.1 - 0.0019 18.7 37.6 0.66 10.6 3.3 5.4 2 2 1 4 4 4 3 Syntaxin 6, N-terminal DUF1664 PF07889.12 KFO95422.1 - 0.0022 18.0 43.1 0.59 10.2 0.2 7.0 1 1 6 7 7 7 3 Protein of unknown function (DUF1664) Filament PF00038.21 KFO95422.1 - 0.0031 17.2 45.8 0.25 10.9 2.1 4.2 1 1 3 4 4 4 3 Intermediate filament protein NPV_P10 PF05531.12 KFO95422.1 - 0.012 16.0 37.1 0.082 13.4 2.4 7.1 2 2 5 7 7 7 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.9 KFO95422.1 - 0.016 15.3 56.1 0.018 15.0 1.2 5.2 1 1 4 5 5 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EzrA PF06160.12 KFO95422.1 - 0.018 13.2 45.8 3 5.9 25.7 4.3 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA DUF745 PF05335.13 KFO95422.1 - 0.027 14.2 33.1 0.82 9.4 4.8 4.5 2 2 2 4 4 4 0 Protein of unknown function (DUF745) bZIP_1 PF00170.21 KFO95422.1 - 0.047 13.8 0.2 0.047 13.8 0.2 6.6 6 3 2 8 8 6 0 bZIP transcription factor TMPIT PF07851.13 KFO95422.1 - 0.07 12.4 38.9 0.25 10.5 7.2 4.5 1 1 4 5 5 5 0 TMPIT-like protein Fez1 PF06818.15 KFO95422.1 - 0.1 13.1 43.4 3.3 8.1 13.8 4.3 1 1 2 3 3 3 0 Fez1 Cob_adeno_trans PF01923.18 KFO95422.1 - 0.2 11.8 18.1 0.8 9.8 1.0 4.8 1 1 1 3 3 3 0 Cobalamin adenosyltransferase CLZ PF16526.5 KFO95422.1 - 0.38 11.1 38.7 0.88 10.0 0.2 8.3 3 3 6 9 9 9 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels COG2 PF06148.11 KFO95422.1 - 0.49 10.5 42.1 0.39 10.8 3.7 6.2 1 1 2 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 FlaC_arch PF05377.11 KFO95422.1 - 0.59 10.6 49.8 0.29 11.6 3.0 8.5 5 2 3 9 9 8 0 Flagella accessory protein C (FlaC) DUF5082 PF16888.5 KFO95422.1 - 0.7 10.2 43.8 2.8 8.3 3.2 6.6 2 2 4 6 6 6 0 Domain of unknown function (DUF5082) HMMR_N PF15905.5 KFO95422.1 - 1.3 8.4 54.2 0.49 9.8 3.7 4.2 1 1 3 4 4 4 0 Hyaluronan mediated motility receptor N-terminal DUF3584 PF12128.8 KFO95422.1 - 1.4 6.3 40.5 2.3 5.6 8.8 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF3584) ADIP PF11559.8 KFO95422.1 - 2 8.5 44.2 0.52 10.4 4.2 5.7 1 1 3 5 5 5 0 Afadin- and alpha -actinin-Binding Snapin_Pallidin PF14712.6 KFO95422.1 - 2.1 8.8 47.3 1.5 9.3 0.5 7.9 2 1 6 8 8 8 0 Snapin/Pallidin DUF4200 PF13863.6 KFO95422.1 - 3.1 8.2 43.4 3.4 8.1 3.4 5.6 3 1 2 5 5 5 0 Domain of unknown function (DUF4200) YvrJ PF12841.7 KFO95422.1 - 3.1 7.4 15.2 4.6 6.9 0.3 5.3 5 0 0 5 5 5 0 YvrJ protein family Cytochrom_C_2 PF01322.20 KFO95422.1 - 3.2 8.7 17.3 30 5.5 1.8 5.0 1 1 3 5 5 5 0 Cytochrome C' Laminin_II PF06009.12 KFO95422.1 - 4.5 7.3 42.7 2.1 8.4 2.6 5.5 1 1 4 5 5 5 0 Laminin Domain II THOC7 PF05615.13 KFO95422.1 - 4.8 7.5 39.9 0.29 11.4 13.6 5.1 2 1 2 4 4 3 0 Tho complex subunit 7 DUF3698 PF12479.8 KFO95422.1 - 4.8 7.8 6.2 7.6 7.1 1.4 3.2 3 1 0 3 3 2 0 Protein of unknown function (DUF3698) DUF4164 PF13747.6 KFO95422.1 - 6 7.2 31.2 5.3 7.4 0.5 6.9 3 2 4 7 7 7 0 Domain of unknown function (DUF4164) APG6_N PF17675.1 KFO95422.1 - 6.3 7.3 49.2 2.2 8.8 0.1 5.2 2 1 3 5 5 5 0 Apg6 coiled-coil region FOXP-CC PF16159.5 KFO95422.1 - 7.4 7.3 8.9 0.64 10.7 1.3 3.2 3 1 0 3 3 2 0 FOXP coiled-coil domain HALZ PF02183.18 KFO95422.1 - 7.8 6.8 12.9 11 6.3 0.5 4.7 4 1 1 5 5 3 0 Homeobox associated leucine zipper Pkinase PF00069.25 KFO95423.1 - 1.2e-68 231.4 0.1 1.7e-68 230.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO95423.1 - 1.1e-38 133.0 0.0 1.7e-38 132.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFO95423.1 - 3.4e-06 26.6 0.0 5.1e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFO95423.1 - 2.1e-05 24.0 1.4 3.8e-05 23.1 0.8 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFO95423.1 - 2.3e-05 23.5 1.6 3.7e-05 22.8 1.6 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KFO95423.1 - 4.7e-05 23.1 1.0 8.1e-05 22.3 1.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KFO95423.1 - 0.17 11.8 0.1 0.38 10.6 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family BAR_3 PF16746.5 KFO95424.1 - 7.2e-60 202.6 10.2 1.4e-59 201.7 10.2 1.4 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KFO95424.1 - 5.5e-09 36.5 0.0 8.3e-08 32.7 0.0 2.6 2 0 0 2 2 2 1 PH domain PID PF00640.23 KFO95424.1 - 3.5e-06 27.1 0.1 9.6e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFO95424.1 - 1.7e-05 24.9 0.1 3.9e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PH_9 PF15410.6 KFO95424.1 - 0.0043 17.4 0.0 0.016 15.5 0.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.10 KFO95424.1 - 0.0066 16.8 0.0 0.021 15.2 0.0 1.8 1 0 0 1 1 1 1 Plant pleckstrin homology-like region DUF3263 PF11662.8 KFO95424.1 - 0.045 13.6 0.1 0.14 12.0 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3263) PH_17 PF18012.1 KFO95424.1 - 0.079 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 PH domain PH_8 PF15409.6 KFO95424.1 - 0.15 12.3 0.1 3.5 8.0 0.0 3.0 4 0 0 4 4 4 0 Pleckstrin homology domain BAR PF03114.18 KFO95424.1 - 0.18 11.4 6.6 0.3 10.7 5.9 1.7 1 1 0 1 1 1 0 BAR domain WASH-7_N PF14745.6 KFO95425.1 - 7.1e-240 797.4 23.5 7.1e-240 797.4 23.5 2.1 3 0 0 3 3 3 1 WASH complex subunit 7, N-terminal WASH-7_mid PF14744.6 KFO95425.1 - 5.7e-174 578.1 9.0 5.7e-174 578.1 9.0 2.3 2 0 0 2 2 2 1 WASH complex subunit 7 WASH-7_C PF14746.6 KFO95425.1 - 3.8e-76 254.7 3.8 3.8e-76 254.7 3.8 2.5 3 0 0 3 3 3 1 WASH complex subunit 7, C-terminal DUF4598 PF15370.6 KFO95426.1 - 6.6e-15 55.5 2.4 9.2e-15 55.1 2.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) Sigma70_r1_1 PF03979.14 KFO95426.1 - 0.002 18.2 5.7 0.0035 17.3 5.7 1.5 1 0 0 1 1 1 1 Sigma-70 factor, region 1.1 MgtE PF01769.16 KFO95427.1 - 1.9e-51 173.6 11.8 5.3e-30 104.3 0.8 3.0 4 0 0 4 4 4 2 Divalent cation transporter DUF3262 PF11660.8 KFO95427.1 - 0.26 11.7 6.7 17 5.9 0.6 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3262) Sulfotransfer_2 PF03567.14 KFO95428.1 - 3.7e-69 233.4 8.3 4.7e-69 233.1 8.3 1.1 1 0 0 1 1 1 1 Sulfotransferase family Pyr_redox_2 PF07992.14 KFO95429.1 - 1.2e-46 159.3 0.0 1.5e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFO95429.1 - 1.2e-26 93.1 0.0 5e-26 91.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFO95429.1 - 3.3e-16 59.6 1.0 5.9e-16 58.8 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFO95429.1 - 4.6e-12 45.8 0.0 6.3e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase CBFD_NFYB_HMF PF00808.23 KFO95430.1 - 5.3e-29 100.3 0.4 7.9e-29 99.7 0.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFO95430.1 - 7e-06 26.4 0.0 1e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KFO95430.1 - 0.0014 18.6 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.6 KFO95430.1 - 0.0015 18.6 0.0 0.0022 18.1 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 KFO95430.1 - 0.12 12.9 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Bromo_TP PF07524.13 KFO95430.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated Kelch_5 PF13854.6 KFO95431.1 - 1.4e-32 111.1 4.9 1.1e-06 28.4 0.0 5.7 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 KFO95431.1 - 6.8e-28 96.4 2.1 1.6e-07 31.4 0.0 5.5 4 1 0 4 4 4 4 Galactose oxidase, central domain Kelch_1 PF01344.25 KFO95431.1 - 9.4e-25 85.9 7.2 2.9e-05 23.6 0.2 5.7 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 KFO95431.1 - 1.4e-19 69.8 0.2 0.00063 19.7 0.0 5.5 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KFO95431.1 - 3.7e-19 68.3 4.5 0.01 16.1 0.0 5.7 5 0 0 5 5 5 5 Kelch motif Kelch_2 PF07646.15 KFO95431.1 - 2.2e-17 62.3 6.1 0.0012 18.8 0.0 5.8 5 0 0 5 5 5 5 Kelch motif fn3 PF00041.21 KFO95431.1 - 4.3e-11 43.0 0.8 0.016 15.6 0.0 4.4 4 0 0 4 4 4 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFO95431.1 - 0.064 13.8 0.2 0.86 10.2 0.0 2.8 3 0 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain Glyco_transf_8 PF01501.20 KFO95432.1 - 5.1e-52 177.0 0.0 6.2e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KFO95432.1 - 0.0001 21.8 0.1 0.00019 20.9 0.1 1.5 1 1 0 1 1 1 1 Glucosyltransferase 24 UDG PF03167.19 KFO95433.1 - 2e-18 66.9 0.0 3e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily GAGA_bind PF06217.12 KFO95433.1 - 0.36 11.1 5.1 0.66 10.2 5.1 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4516 PF14990.6 KFO95434.1 - 8.6e-25 86.2 1.4 1e-24 86.0 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4516) HSP90 PF00183.18 KFO95435.1 - 3.5e-229 762.0 28.8 6.1e-229 761.2 28.8 1.4 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KFO95435.1 - 4.5e-15 56.1 0.5 8.7e-15 55.2 0.5 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFO95435.1 - 4e-12 46.1 0.4 1.4e-11 44.4 0.4 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AbiJ_NTD5 PF18865.1 KFO95435.1 - 0.097 12.5 1.3 0.21 11.4 0.2 2.2 2 0 0 2 2 2 0 AbiJ N-terminal domain 5 DUF4518 PF15008.6 KFO95435.1 - 0.12 11.5 4.3 1.1 8.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) MH1 PF03165.16 KFO95435.1 - 0.25 11.6 1.9 0.86 9.8 0.0 2.8 3 0 0 3 3 3 0 MH1 domain 5_nucleotid PF05761.14 KFO95436.1 - 7.4e-155 516.3 8.5 8.4e-155 516.1 8.5 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.6 KFO95436.1 - 1.1e-05 25.6 0.4 0.00044 20.4 0.0 3.2 3 1 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Mu-transpos_C PF09299.11 KFO95436.1 - 0.11 12.5 0.2 0.79 9.7 0.1 2.6 2 0 0 2 2 2 0 Mu transposase, C-terminal Hydrolase PF00702.26 KFO95436.1 - 0.17 12.2 0.0 0.41 10.9 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase RVT_1 PF00078.27 KFO95437.1 - 0.085 12.4 0.0 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Biopterin_H PF00351.21 KFO95438.1 - 1.2e-175 583.4 0.0 1.5e-175 583.0 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 KFO95438.1 - 3.5e-08 33.1 0.0 7.7e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 KFO95438.1 - 0.0054 17.3 0.2 0.033 14.8 0.0 2.1 2 0 0 2 2 2 1 ACT domain Biopterin_H PF00351.21 KFO95439.1 - 1.1e-171 570.4 1.7 1.3e-171 570.1 1.7 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase Insulin PF00049.18 KFO95440.1 - 3.8e-14 53.4 8.5 3.9e-12 47.0 5.9 2.5 2 1 0 2 2 2 1 Insulin/IGF/Relaxin family Pro-MCH PF05824.12 KFO95441.1 - 3e-42 142.5 0.0 4.2e-42 142.0 0.0 1.2 1 0 0 1 1 1 1 Pro-melanin-concentrating hormone (Pro-MCH) UvrD_C PF13361.6 KFO95442.1 - 0.018 14.4 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF1285 PF06938.11 KFO95442.1 - 0.034 14.2 0.0 0.095 12.7 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1285) DUF1719 PF08224.11 KFO95442.1 - 0.039 13.1 1.3 0.93 8.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1719) WD40 PF00400.32 KFO95443.1 - 2.4e-14 53.5 1.4 5.3e-05 23.9 0.1 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO95443.1 - 0.00078 19.7 0.0 0.0078 16.5 0.0 2.6 1 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain CCDC53 PF10152.9 KFO95444.1 - 1.8e-50 171.3 1.1 2.2e-50 171.0 1.1 1.1 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex Frag1 PF10277.9 KFO95445.1 - 9.3e-50 169.2 17.0 1e-49 169.0 17.0 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Virul_fac_BrkB PF03631.15 KFO95445.1 - 0.019 14.6 4.8 0.76 9.3 0.2 2.1 1 1 0 2 2 2 0 Virulence factor BrkB Stealth_CR2 PF11380.8 KFO95446.1 - 7.3e-46 154.8 2.4 2.2e-45 153.3 0.4 2.7 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 GlcNAc-1_reg PF18440.1 KFO95446.1 - 5.1e-45 151.7 0.1 2e-44 149.7 0.1 2.2 1 0 0 1 1 1 1 Putative GlcNAc-1 phosphotransferase regulatory domain Stealth_CR4 PF17103.5 KFO95446.1 - 3.5e-24 84.4 3.0 9e-24 83.1 1.7 2.3 2 0 0 2 2 2 1 Stealth protein CR4, conserved region 4 Stealth_CR3 PF17102.5 KFO95446.1 - 7.3e-19 67.4 7.0 1.9e-18 66.1 7.0 1.8 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Notch PF00066.17 KFO95446.1 - 1.6e-15 57.2 31.9 5.1e-09 36.4 12.6 2.4 2 0 0 2 2 2 2 LNR domain Stealth_CR1 PF17101.5 KFO95446.1 - 8.4e-12 44.6 0.0 1.9e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 DMAP_binding PF06464.11 KFO95446.1 - 1.1e-10 42.3 0.6 3.7e-10 40.6 0.6 2.0 1 0 0 1 1 1 1 DMAP1-binding Domain EF-hand_1 PF00036.32 KFO95446.1 - 0.025 14.1 0.0 0.072 12.7 0.0 1.9 1 0 0 1 1 1 0 EF hand Takusan PF04822.13 KFO95446.1 - 0.1 12.5 1.6 0.56 10.1 1.6 2.3 1 0 0 1 1 1 0 Takusan EF-hand_7 PF13499.6 KFO95446.1 - 0.11 12.9 0.1 0.81 10.2 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 KFO95446.1 - 0.16 11.6 0.1 0.42 10.2 0.1 1.8 1 0 0 1 1 1 0 EF hand Cor1 PF04803.12 KFO95447.1 - 3.7e-60 201.9 30.2 6.6e-60 201.1 30.2 1.4 1 0 0 1 1 1 1 Cor1/Xlr/Xmr conserved region Peptidase_C65 PF10275.9 KFO95447.1 - 0.0011 18.5 7.5 0.0014 18.1 7.5 1.3 1 0 0 1 1 1 1 Peptidase C65 Otubain T3SSipB PF16535.5 KFO95447.1 - 0.21 12.1 16.8 0.52 10.8 16.6 1.8 1 1 0 1 1 1 0 Type III cell invasion protein SipB Focal_AT PF03623.13 KFO95447.1 - 1.1 9.3 10.8 6.7 6.7 0.2 2.2 2 0 0 2 2 2 0 Focal adhesion targeting region Nucleoporin_FG2 PF15967.5 KFO95447.1 - 9.5 4.6 8.2 10 4.5 8.2 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region CDP-OH_P_transf PF01066.21 KFO95448.1 - 2.1e-12 47.6 4.9 6.2e-12 46.1 0.0 3.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF4131 PF13567.6 KFO95448.1 - 6.2 6.4 7.8 0.84 9.3 1.9 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Pkinase PF00069.25 KFO95449.1 - 2.1e-70 237.1 0.0 3e-70 236.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 KFO95449.1 - 1.4e-51 173.0 5.2 3.5e-17 62.8 0.1 4.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFO95449.1 - 4.7e-44 147.9 12.3 3.9e-08 33.4 0.1 7.5 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFO95449.1 - 5.9e-44 147.9 4.1 3.3e-09 37.1 0.0 6.6 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 KFO95449.1 - 7.6e-38 127.3 7.6 8.4e-06 26.0 0.0 9.0 9 0 0 9 9 9 7 Ankyrin repeat Pkinase_Tyr PF07714.17 KFO95449.1 - 7e-34 117.3 0.0 1.2e-33 116.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.6 KFO95449.1 - 7.7e-34 111.9 8.3 9.2e-05 22.6 0.0 8.8 8 0 0 8 8 8 7 Ankyrin repeat Kdo PF06293.14 KFO95449.1 - 4.3e-06 26.2 0.1 1.5e-05 24.4 0.1 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFO95449.1 - 0.00012 21.8 0.0 0.00024 20.7 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Roc PF08477.13 KFO95449.1 - 0.0049 17.1 0.1 2.2 8.5 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 KFO95449.1 - 0.015 15.8 0.4 0.048 14.1 0.0 2.0 3 0 0 3 3 2 0 AAA domain Kinase-like PF14531.6 KFO95449.1 - 0.026 13.8 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 KFO95449.1 - 0.033 13.8 0.0 0.071 12.7 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 KFO95449.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3847 PF12958.7 KFO95449.1 - 0.065 13.4 0.3 0.28 11.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) G-alpha PF00503.20 KFO95449.1 - 0.088 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit ABC_tran PF00005.27 KFO95449.1 - 0.099 13.2 0.1 0.35 11.4 0.1 1.9 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KFO95449.1 - 0.1 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KFO95449.1 - 0.13 12.6 0.2 0.46 10.8 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain Death PF00531.22 KFO95450.1 - 4.2e-21 74.9 0.6 7e-20 71.0 0.0 3.1 3 1 0 3 3 3 1 Death domain COR PF16095.5 KFO95450.1 - 2.8e-08 33.8 0.1 4.7e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Peptidase_C1 PF00112.23 KFO95451.1 - 7.2e-89 297.6 3.1 1.1e-88 297.0 3.1 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KFO95451.1 - 4.2e-13 49.5 1.5 8.1e-13 48.6 1.5 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KFO95451.1 - 2.3e-06 26.6 2.9 0.00027 19.8 1.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Styelin PF17562.2 KFO95451.1 - 0.057 13.8 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 Styelin FBPase PF00316.20 KFO95452.1 - 5e-78 260.9 0.4 6.7e-78 260.5 0.4 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 KFO95452.1 - 1.2e-05 25.0 0.0 2.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Inositol monophosphatase family Peptidase_M1 PF01433.20 KFO95453.1 - 6.7e-21 74.9 0.0 1.5e-20 73.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KFO95453.1 - 6.1e-17 61.7 0.5 1.5e-16 60.4 0.2 1.9 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KFO95453.1 - 1e-06 29.1 0.0 7e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF5048 PF16467.5 KFO95453.1 - 0.084 13.2 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5048) Fanconi_C PF02106.15 KFO95454.1 - 1.2e-248 826.4 26.1 1.4e-248 826.2 26.1 1.0 1 0 0 1 1 1 1 Fanconi anaemia group C protein EF-hand_2 PF09068.11 KFO95454.1 - 0.0021 18.2 5.5 0.56 10.4 0.0 3.5 2 1 0 2 2 2 2 EF hand Patched PF02460.18 KFO95455.1 - 8.9e-74 249.0 20.4 2.4e-42 145.0 1.3 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 KFO95455.1 - 2.6e-43 147.5 4.0 2.6e-43 147.5 4.0 2.6 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation SNF2_N PF00176.23 KFO95456.1 - 2.2e-53 181.2 0.5 3.3e-53 180.7 0.5 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFO95456.1 - 1.3e-20 73.8 0.0 1e-19 70.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFO95456.1 - 7.7e-11 42.3 0.1 4.1e-10 39.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFO95456.1 - 1.8e-07 31.1 0.0 4.3e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KFO95456.1 - 8.1e-07 28.5 0.3 2.6e-06 26.8 0.2 1.8 1 1 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HDA2-3 PF11496.8 KFO95456.1 - 1e-06 28.2 0.4 0.00014 21.1 0.1 3.0 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KFO95456.1 - 0.0014 18.3 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase SMN PF06003.12 KFO95456.1 - 0.024 13.9 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) AAA_34 PF13872.6 KFO95456.1 - 0.047 12.6 0.1 3.8 6.3 0.0 3.0 4 0 0 4 4 4 0 P-loop containing NTP hydrolase pore-1 VIGSSK PF14773.6 KFO95457.1 - 1e-07 32.0 0.1 1e-07 32.0 0.1 2.3 3 0 0 3 3 3 1 Helicase-associated putative binding domain, C-terminal adh_short PF00106.25 KFO95458.1 - 2.5e-39 134.8 0.0 3.2e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFO95458.1 - 2.6e-17 63.2 0.0 3.3e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFO95458.1 - 7.2e-05 22.8 0.1 0.0006 19.8 0.1 1.9 2 0 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 KFO95458.1 - 0.0097 16.2 0.2 0.066 13.5 0.1 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KFO95458.1 - 0.034 14.0 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding Shikimate_DH PF01488.20 KFO95458.1 - 0.09 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 KFO95458.1 - 0.096 12.1 0.3 11 5.3 0.1 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KFO95458.1 - 0.11 12.4 0.2 0.2 11.5 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TPT PF03151.16 KFO95459.1 - 2.2e-19 69.9 11.2 2.5e-19 69.7 11.2 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KFO95459.1 - 3.8e-05 23.0 13.8 5.1e-05 22.6 13.8 1.2 1 0 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 KFO95459.1 - 0.0013 17.8 4.4 0.0013 17.8 4.4 2.6 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Phage_holin_3_3 PF16083.5 KFO95459.1 - 0.11 12.6 3.0 2.1 8.5 0.2 2.5 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III zf-H2C2_2 PF13465.6 KFO95460.1 - 2e-14 53.2 7.1 7.7e-07 29.3 0.2 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFO95460.1 - 6.8e-10 38.9 4.4 2.5e-05 24.5 0.7 3.1 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFO95460.1 - 9.7e-07 28.6 1.4 2.5e-06 27.4 0.2 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KFO95460.1 - 6e-06 26.7 3.7 0.00042 20.9 0.4 3.0 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO95460.1 - 0.00011 22.4 0.2 0.0016 18.7 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFO95460.1 - 0.00013 22.2 0.6 0.00054 20.3 0.1 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFO95460.1 - 0.021 15.1 2.4 0.094 13.0 2.3 1.9 1 1 1 2 2 2 0 C2H2-type zinc ribbon MRC1 PF09444.10 KFO95460.1 - 0.044 14.3 6.5 0.078 13.5 6.5 1.3 1 0 0 1 1 1 0 MRC1-like domain Nucleo_P87 PF07267.11 KFO95460.1 - 0.048 12.5 1.9 0.053 12.4 1.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HABP4_PAI-RBP1 PF04774.15 KFO95461.1 - 1.4e-13 51.7 11.9 2e-13 51.2 2.7 2.7 2 1 1 3 3 3 2 Hyaluronan / mRNA binding family IHABP4_N PF16174.5 KFO95461.1 - 8.3e-07 29.8 4.2 8.3e-07 29.8 4.2 2.3 2 0 0 2 2 2 1 Intracellular hyaluronan-binding protein 4 N-terminal RPA_interact_M PF14767.6 KFO95461.1 - 0.01 16.4 0.1 0.024 15.2 0.1 1.7 1 0 0 1 1 1 0 Replication protein A interacting middle DSPn PF14671.6 KFO95462.1 - 4.9e-56 189.1 3.4 6.7e-55 185.4 1.9 2.4 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KFO95462.1 - 2.1e-15 56.7 0.0 3.8e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFO95462.1 - 4.2e-06 27.0 0.0 6.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KFO95462.1 - 1.8e-05 24.4 0.0 3.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFO95462.1 - 0.0084 16.1 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KFO95462.1 - 0.065 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family AhpC-TSA_2 PF13911.6 KFO95463.1 - 5.8e-19 68.3 0.0 6.9e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 KFO95463.1 - 0.027 14.2 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 Redoxin AhpC-TSA PF00578.21 KFO95463.1 - 0.029 14.3 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family LRR_10 PF18805.1 KFO95463.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat DUF3350 PF11830.8 KFO95464.1 - 0.0075 16.6 1.8 0.0075 16.6 1.8 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3350) SBD_N PF07005.11 KFO95464.1 - 0.19 11.4 0.1 0.2 11.4 0.1 1.0 1 0 0 1 1 1 0 Sugar-binding N-terminal domain CFC PF09443.10 KFO95465.1 - 2.6e-15 56.0 11.6 2.6e-15 56.0 11.6 2.5 3 0 0 3 3 3 1 Cripto_Frl-1_Cryptic (CFC) EGF_2 PF07974.13 KFO95465.1 - 0.014 15.8 9.1 0.014 15.8 9.1 2.7 2 1 0 2 2 2 0 EGF-like domain EGF PF00008.27 KFO95465.1 - 0.017 15.4 6.6 0.017 15.4 6.6 2.0 2 0 0 2 2 2 0 EGF-like domain LRR_8 PF13855.6 KFO95466.1 - 2.1e-21 75.4 16.4 1.4e-08 34.3 1.4 4.3 2 2 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFO95466.1 - 3e-16 59.3 21.6 3.5e-07 30.5 4.5 5.1 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFO95466.1 - 0.00012 22.2 14.1 2.5 9.0 0.1 5.6 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.6 KFO95466.1 - 0.0027 17.6 12.5 2.9 8.2 0.4 5.2 5 0 0 5 5 5 2 Leucine Rich repeat RsmF_methylt_CI PF17126.5 KFO95466.1 - 0.076 13.1 0.1 26 5.0 0.0 3.6 2 1 0 2 2 2 0 RsmF rRNA methyltransferase first C-terminal domain F5_F8_type_C PF00754.25 KFO95467.1 - 1.1e-29 103.1 1.9 1.6e-29 102.6 0.8 1.7 2 0 0 2 2 2 1 F5/8 type C domain Laminin_G_2 PF02210.24 KFO95467.1 - 3.4e-24 85.8 0.6 5.6e-24 85.1 0.6 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFO95467.1 - 3.3e-13 50.0 0.1 5.7e-13 49.2 0.1 1.3 1 0 0 1 1 1 1 Laminin G domain Lipase_GDSL_2 PF13472.6 KFO95468.1 - 0.0048 17.3 0.0 0.0088 16.5 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 KFO95468.1 - 0.0083 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 OSK domain Lipase_GDSL PF00657.22 KFO95468.1 - 0.18 11.8 0.0 0.68 9.9 0.0 1.9 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.16 KFO95469.1 - 1.6e-35 122.7 38.5 2.1e-34 119.0 38.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFO95469.1 - 3.9e-13 49.0 22.2 2.3e-10 39.9 21.8 3.6 2 1 0 2 2 2 2 MFS_1 like family Spin-Ssty PF02513.17 KFO95470.1 - 1.2e-76 252.3 7.8 6.5e-28 96.2 0.2 3.2 3 0 0 3 3 3 3 Spin/Ssty Family Thioredoxin_8 PF13905.6 KFO95471.1 - 1e-16 61.0 0.0 1.5e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 KFO95471.1 - 4.2e-08 33.1 1.7 0.00092 19.2 0.1 2.1 1 1 1 2 2 2 2 Thioredoxin Redoxin PF08534.10 KFO95471.1 - 0.0012 18.6 0.1 0.0018 18.0 0.1 1.3 1 1 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 KFO95471.1 - 0.0048 17.3 0.1 0.0078 16.7 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KFO95471.1 - 0.01 15.8 0.1 0.022 14.7 0.1 1.6 1 1 0 1 1 1 0 AhpC/TSA family KaiB PF07689.12 KFO95471.1 - 0.066 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 KaiB domain Eco57I PF07669.11 KFO95471.1 - 0.071 13.6 0.1 0.1 13.1 0.1 1.2 1 0 0 1 1 1 0 Eco57I restriction-modification methylase Thioredoxin_3 PF13192.6 KFO95471.1 - 0.12 12.4 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin domain CKS PF01111.19 KFO95472.1 - 5.6e-38 129.0 3.4 6.4e-38 128.9 3.4 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Peptidase_M29 PF02073.15 KFO95472.1 - 0.031 13.1 0.0 0.032 13.0 0.0 1.0 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) Ribosomal_L7Ae PF01248.26 KFO95473.1 - 1e-21 76.4 0.3 2.5e-21 75.2 0.3 1.7 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Sema PF01403.19 KFO95475.1 - 2.9e-157 523.8 0.1 4.7e-157 523.1 0.1 1.3 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 KFO95475.1 - 3.8e-08 33.7 3.4 1.4e-07 32.0 3.4 2.0 1 0 0 1 1 1 1 Plexin repeat ig PF00047.25 KFO95475.1 - 1.5e-06 28.3 1.1 3.5e-06 27.1 0.1 2.1 3 0 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 KFO95475.1 - 0.00024 21.4 0.0 0.00078 19.7 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain Ig_5 PF16681.5 KFO95475.1 - 0.00028 21.2 1.3 0.00062 20.1 0.1 2.2 2 0 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_3 PF13927.6 KFO95475.1 - 0.0005 20.6 0.0 0.0013 19.3 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFO95475.1 - 0.00088 19.3 0.5 0.0023 18.0 0.1 1.9 2 0 0 2 2 2 1 Immunoglobulin I-set domain DUF5472 PF17566.2 KFO95475.1 - 0.29 11.1 3.7 12 5.9 0.6 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5472) PSI_integrin PF17205.3 KFO95475.1 - 0.35 10.6 3.3 0.56 10.0 1.5 2.3 2 0 0 2 2 2 0 Integrin plexin domain Ras PF00071.22 KFO95476.1 - 2.4e-50 170.3 0.1 2.8e-50 170.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO95476.1 - 4.9e-17 62.3 0.0 9.8e-17 61.3 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO95476.1 - 6.2e-07 29.0 0.0 8.9e-07 28.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFO95476.1 - 0.00048 20.1 2.1 0.33 10.9 0.2 2.3 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFO95476.1 - 0.00066 19.7 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 KFO95476.1 - 0.0056 15.7 0.7 0.37 9.7 0.3 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KFO95476.1 - 0.032 13.9 0.4 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KFO95476.1 - 0.04 14.3 0.1 0.062 13.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1_Xtn PF16897.5 KFO95476.1 - 0.092 12.8 0.2 0.34 10.9 0.1 1.8 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain DUF2408 PF10303.9 KFO95476.1 - 0.11 13.0 5.2 1.9 9.1 4.7 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2408) AAA_22 PF13401.6 KFO95476.1 - 0.14 12.4 0.4 0.71 10.1 0.4 2.3 1 1 0 1 1 1 0 AAA domain Pkinase_Tyr PF07714.17 KFO95477.1 - 6.3e-85 284.6 0.4 8.9e-85 284.1 0.4 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO95477.1 - 1.6e-46 158.8 0.1 2.3e-46 158.3 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFO95477.1 - 8.8e-40 134.7 0.3 7.4e-21 74.0 0.1 2.5 2 0 0 2 2 2 2 SH2 domain Kdo PF06293.14 KFO95477.1 - 0.00028 20.3 0.1 0.00047 19.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFO95477.1 - 0.0081 15.1 0.1 0.013 14.5 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain p25-alpha PF05517.12 KFO95478.1 - 2.3e-67 226.0 6.0 2.5e-67 225.9 6.0 1.0 1 0 0 1 1 1 1 p25-alpha EF-hand_7 PF13499.6 KFO95478.1 - 0.02 15.3 0.0 0.045 14.2 0.0 1.7 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 KFO95478.1 - 1.4 8.6 4.4 1.6 8.4 0.0 3.1 4 0 0 4 4 4 0 EF hand ECH_1 PF00378.20 KFO95479.1 - 1.4e-58 198.1 0.1 1.6e-58 198.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFO95479.1 - 5.9e-30 104.9 0.2 6.2e-29 101.5 0.1 1.9 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Vert_IL3-reg_TF PF06529.11 KFO95480.1 - 1.7e-181 602.7 21.7 2.4e-181 602.2 21.7 1.2 1 0 0 1 1 1 1 Vertebrate interleukin-3 regulated transcription factor bZIP_2 PF07716.15 KFO95480.1 - 1.2e-14 54.1 9.6 1.2e-14 54.1 9.6 2.8 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 KFO95480.1 - 0.00026 21.0 7.1 0.00026 21.0 7.1 3.1 3 0 0 3 3 3 1 bZIP transcription factor Pkinase_Tyr PF07714.17 KFO95481.1 - 7.6e-87 290.9 0.0 1e-86 290.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO95481.1 - 5.2e-38 130.9 0.0 7.6e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kringle PF00051.18 KFO95481.1 - 4.3e-25 87.8 1.7 2.2e-24 85.6 1.7 2.2 2 0 0 2 2 2 1 Kringle domain I-set PF07679.16 KFO95481.1 - 5.8e-18 64.7 0.0 1.1e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO95481.1 - 1.6e-15 57.5 1.9 2.1e-15 57.1 0.1 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Fz PF01392.22 KFO95481.1 - 1.5e-11 44.9 2.7 1.5e-11 44.9 2.7 2.1 2 0 0 2 2 2 1 Fz domain Ig_2 PF13895.6 KFO95481.1 - 6.8e-09 36.0 0.0 1.9e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFO95481.1 - 2.6e-07 30.8 0.3 3.7e-05 23.9 0.3 2.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFO95481.1 - 5.7e-07 29.6 0.0 1.4e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain TMEM154 PF15102.6 KFO95481.1 - 0.18 11.7 0.1 0.18 11.7 0.1 2.2 3 0 0 3 3 3 0 TMEM154 protein family Aminotran_1_2 PF00155.21 KFO95482.1 - 1.8e-41 142.6 0.0 2.1e-41 142.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II PAD PF03068.15 KFO95482.1 - 0.0078 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) Cys_Met_Meta_PP PF01053.20 KFO95482.1 - 0.074 11.6 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PBD PF00786.28 KFO95483.1 - 1.1e-05 25.7 0.1 1.5e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 P21-Rho-binding domain Complex1_LYR PF05347.15 KFO95484.1 - 8.1e-08 32.2 0.3 1.3e-07 31.6 0.3 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF2748 PF10871.8 KFO95484.1 - 0.0076 14.9 1.3 0.0085 14.8 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2748) KH_9 PF17904.1 KFO95484.1 - 0.023 15.0 0.3 0.028 14.8 0.3 1.2 1 0 0 1 1 1 0 FMRP KH0 domain DUF2570 PF10828.8 KFO95484.1 - 0.03 14.1 0.8 0.041 13.7 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Bt_P21 PF05560.11 KFO95484.1 - 0.056 13.1 0.0 0.063 12.9 0.0 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein DUF924 PF06041.11 KFO95484.1 - 0.058 13.5 0.0 0.062 13.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) HIT PF01230.23 KFO95485.1 - 9.1e-25 87.3 0.0 9.9e-25 87.1 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KFO95485.1 - 6.4e-15 55.6 0.0 7.5e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Yae1_N PF09811.9 KFO95486.1 - 4.7e-10 39.0 37.5 4.6e+03 -2.6 37.5 4.2 1 1 0 1 1 1 0 Essential protein Yae1, N terminal wnt PF00110.19 KFO95487.1 - 1.8e-124 415.3 23.2 2.1e-124 415.1 23.2 1.0 1 0 0 1 1 1 1 wnt family COG6 PF06419.11 KFO95487.1 - 0.29 9.3 0.2 0.41 8.8 0.2 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 DSPc PF00782.20 KFO95488.1 - 5.7e-12 45.6 0.0 1.6e-11 44.1 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFO95488.1 - 3e-08 33.5 0.0 6.1e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KFO95488.1 - 0.00053 19.7 0.0 0.0016 18.1 0.0 1.7 1 1 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 KFO95488.1 - 0.0051 16.8 0.0 0.016 15.2 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family Homeodomain PF00046.29 KFO95489.1 - 2e-21 75.6 2.2 2e-21 75.6 2.2 1.5 2 0 0 2 2 2 1 Homeodomain JHD PF17811.1 KFO95490.1 - 5.8e-40 136.0 1.0 6.2e-39 132.7 0.1 2.9 2 0 0 2 2 2 1 Jumonji helical domain JmjC PF02373.22 KFO95490.1 - 1.3e-12 48.1 0.3 1.3e-12 48.1 0.3 2.4 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KFO95490.1 - 1.6e-07 31.4 0.1 1.6e-07 31.4 0.1 2.8 2 1 0 2 2 2 1 Cupin-like domain Ninjurin PF04923.12 KFO95493.1 - 2.7e-37 126.8 5.8 3e-37 126.7 5.8 1.0 1 0 0 1 1 1 1 Ninjurin SseC PF04888.12 KFO95493.1 - 0.095 12.3 0.7 0.54 9.8 0.1 1.9 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family DUF4231 PF14015.6 KFO95493.1 - 0.2 12.1 0.8 0.5 10.9 0.3 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF4231) Neur_chan_memb PF02932.16 KFO95493.1 - 0.27 11.3 2.8 0.26 11.3 1.7 1.5 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CARD PF00619.21 KFO95494.1 - 8.1e-08 32.2 0.4 1.4e-07 31.5 0.4 1.5 1 0 0 1 1 1 1 Caspase recruitment domain Cytokin_check_N PF10407.9 KFO95494.1 - 0.018 15.0 2.9 2.2 8.3 0.6 2.5 2 1 1 3 3 3 0 Cdc14 phosphatase binding protein N-terminus DUF1640 PF07798.11 KFO95494.1 - 0.16 12.0 1.2 0.21 11.7 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) NADH5_C PF06455.11 KFO95494.1 - 0.22 11.1 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus Sushi PF00084.20 KFO95495.1 - 0.0012 19.4 0.1 0.0019 18.7 0.1 1.4 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) DUF728 PF05304.12 KFO95495.1 - 0.01 15.7 0.5 0.013 15.3 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF728) Shisa PF13908.6 KFO95495.1 - 0.017 15.4 0.2 0.022 15.0 0.2 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RhoGEF PF00621.20 KFO95496.1 - 2.3e-47 161.6 4.6 2.7e-47 161.4 0.8 2.3 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 KFO95496.1 - 6.7e-22 78.0 0.4 3.1e-13 50.1 0.0 2.6 2 0 0 2 2 2 2 PH domain FYVE PF01363.21 KFO95496.1 - 3.1e-14 52.9 14.3 2.6e-13 49.9 14.5 2.4 2 0 0 2 2 2 1 FYVE zinc finger PH_13 PF16652.5 KFO95496.1 - 0.00011 22.1 1.3 0.073 12.9 2.1 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 KFO95496.1 - 0.00034 20.6 1.5 0.00048 20.1 0.5 1.7 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 KFO95496.1 - 0.06 13.7 2.5 8.3 6.8 0.1 3.2 3 0 0 3 3 3 0 Pleckstrin homology domain PH_16 PF17838.1 KFO95496.1 - 0.16 11.8 0.1 0.16 11.8 0.1 2.6 3 0 0 3 3 3 0 PH domain PH_11 PF15413.6 KFO95496.1 - 0.2 12.1 2.8 1.9 8.9 0.1 3.1 2 1 1 3 3 3 0 Pleckstrin homology domain FYVE_2 PF02318.16 KFO95496.1 - 1.6 9.0 23.4 0.11 12.8 13.8 3.1 3 0 0 3 3 3 0 FYVE-type zinc finger PH_2 PF08458.10 KFO95496.1 - 4.9 7.6 5.7 2.8 8.4 0.3 2.9 3 0 0 3 3 3 0 Plant pleckstrin homology-like region zf-HC5HC2H PF13771.6 KFO95497.1 - 6.9e-14 51.9 2.2 6.9e-14 51.9 2.2 3.6 3 0 0 3 3 3 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFO95497.1 - 4.5e-06 26.8 7.0 4.5e-06 26.8 7.0 3.4 2 1 1 3 3 3 2 PHD-zinc-finger like domain zf-RING_2 PF13639.6 KFO95497.1 - 0.001 19.4 10.1 0.001 19.4 10.1 4.4 4 1 0 4 4 4 1 Ring finger domain tRNA-synt_1 PF00133.22 KFO95498.1 - 8.2e-235 780.7 0.0 4.4e-234 778.3 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KFO95498.1 - 7.8e-26 90.9 0.3 2.4e-25 89.3 0.1 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KFO95498.1 - 7.7e-14 51.2 0.3 0.001 17.9 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KFO95498.1 - 0.0091 15.4 0.0 0.033 13.5 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Cation_ATPase_C PF00689.21 KFO95499.1 - 9.1e-45 152.6 5.4 1.9e-44 151.5 2.6 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KFO95499.1 - 9.2e-34 116.5 14.3 2.9e-25 88.8 1.5 2.9 3 0 0 3 3 3 2 E1-E2 ATPase ATP_Ca_trans_C PF12424.8 KFO95499.1 - 6.9e-27 93.7 0.1 1.9e-26 92.3 0.1 1.9 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal Cation_ATPase PF13246.6 KFO95499.1 - 1.2e-17 63.8 0.0 2.5e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFO95499.1 - 3.3e-15 56.9 0.2 8e-14 52.4 0.2 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFO95499.1 - 3.8e-15 55.3 0.0 2e-14 53.0 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFO95499.1 - 5.1e-08 33.0 0.7 6.9e-06 26.0 0.2 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase SNF PF00209.18 KFO95500.1 - 7.4e-247 820.2 39.0 8.4e-247 820.0 39.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 KFO95501.1 - 4.5e-233 774.7 41.1 5.2e-233 774.5 41.1 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family 7tm_1 PF00001.21 KFO95502.1 - 5.5e-70 235.7 0.5 7.9e-70 235.2 0.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFO95502.1 - 1e-08 34.9 13.5 3.7e-05 23.2 5.5 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFO95502.1 - 2.4e-06 27.5 11.1 5e-05 23.2 6.3 2.8 2 1 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFO95502.1 - 1.1e-05 25.2 10.5 1.1e-05 25.2 10.5 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx ATG7_N PF16420.5 KFO95503.1 - 4.4e-92 308.9 0.0 6.2e-92 308.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KFO95503.1 - 1.9e-56 191.1 0.0 2.9e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 KFO95503.1 - 0.034 14.2 0.1 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase VGLL4 PF15245.6 KFO95504.1 - 2.6e-104 348.0 3.7 3.4e-103 344.4 6.1 1.6 2 0 0 2 2 2 1 Transcription cofactor vestigial-like protein 4 Vg_Tdu PF07545.14 KFO95504.1 - 5.3e-05 22.9 0.0 0.25 11.2 0.0 2.5 2 0 0 2 2 2 2 Vestigial/Tondu family DUF3868 PF12984.7 KFO95504.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3868) Tam41_Mmp37 PF09139.11 KFO95505.1 - 1.8e-87 293.8 0.0 1.9e-87 293.7 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Synapsin_C PF02750.14 KFO95506.1 - 1e-135 449.7 0.8 1.2e-135 449.5 0.8 1.1 1 0 0 1 1 1 1 Synapsin, ATP binding domain Synapsin PF02078.16 KFO95506.1 - 1.6e-11 44.4 0.1 9e-11 42.0 0.0 2.1 2 0 0 2 2 2 1 Synapsin, N-terminal domain TIMP PF00965.17 KFO95507.1 - 1.5e-58 197.6 3.5 1.6e-58 197.5 3.5 1.0 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.21 KFO95507.1 - 0.029 14.2 0.1 0.043 13.6 0.1 1.3 1 0 0 1 1 1 0 UNC-6/NTR/C345C module PPARgamma_N PF12577.8 KFO95508.1 - 7.8e-35 119.4 1.2 1.9e-34 118.1 1.2 1.7 1 0 0 1 1 1 1 PPAR gamma N-terminal region zf-C4 PF00105.18 KFO95508.1 - 1.5e-27 95.8 15.0 2.9e-27 94.9 15.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFO95508.1 - 1e-16 61.2 1.0 2.2e-16 60.1 0.4 1.9 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor Tmemb_55A PF09788.9 KFO95508.1 - 0.019 14.0 3.7 0.031 13.3 3.7 1.3 1 0 0 1 1 1 0 Transmembrane protein 55A zinc_ribbon_6 PF14599.6 KFO95508.1 - 4.5 7.4 7.0 0.23 11.5 0.4 2.3 2 0 0 2 2 2 0 Zinc-ribbon tRNA_int_endo_N PF02778.14 KFO95509.1 - 9.6e-19 66.8 0.5 6e-13 48.3 0.3 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain tRNA_int_endo PF01974.17 KFO95509.1 - 1.4e-17 63.5 0.0 2.8e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain zf-CCCH_4 PF18044.1 KFO95510.1 - 1.7e-22 78.7 37.4 1.5e-07 31.0 3.3 5.2 6 0 0 6 6 6 4 CCCH-type zinc finger zf-CCCH PF00642.24 KFO95510.1 - 3.5e-21 74.6 30.4 1.6e-06 27.8 3.3 4.6 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFO95510.1 - 5.9e-21 73.8 34.0 9e-06 25.6 8.3 5.4 4 1 0 4 4 4 4 Zinc finger domain Torus PF16131.5 KFO95510.1 - 4.7e-13 49.8 19.5 0.00047 20.8 1.2 4.5 3 1 1 4 4 4 4 Torus domain zf-CCCH_2 PF14608.6 KFO95510.1 - 3.2e-07 30.6 23.7 0.048 14.1 1.6 4.9 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KFO95510.1 - 4.7e-05 23.6 3.2 4.7e-05 23.6 3.2 3.0 3 0 0 3 3 3 1 Zinc-finger containing family zf-C3HC4 PF00097.25 KFO95510.1 - 5.3e-05 23.0 10.1 5.3e-05 23.0 10.1 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFO95510.1 - 0.00016 21.6 5.6 0.00016 21.6 5.6 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFO95510.1 - 0.00034 20.9 9.6 0.00034 20.9 9.6 3.7 5 0 0 5 5 4 1 Ring finger domain zf-RING_5 PF14634.6 KFO95510.1 - 0.0016 18.4 8.8 0.0016 18.4 8.8 2.7 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFO95510.1 - 0.0038 17.4 9.7 0.0041 17.2 6.1 2.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING MKRN1_C PF15815.5 KFO95510.1 - 0.096 13.1 0.2 0.3 11.5 0.1 1.9 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase makorin-1, C-terminal zf-RING_11 PF17123.5 KFO95510.1 - 0.11 12.3 5.9 0.1 12.3 1.9 3.2 3 1 0 3 3 3 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFO95510.1 - 0.25 11.2 15.8 0.1 12.4 8.9 3.9 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Pkinase_Tyr PF07714.17 KFO95511.1 - 6.1e-63 212.5 0.0 8.2e-63 212.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO95511.1 - 4e-61 206.7 0.0 5.4e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RBD PF02196.15 KFO95511.1 - 1.1e-27 95.8 0.1 2.5e-27 94.7 0.1 1.6 1 0 0 1 1 1 1 Raf-like Ras-binding domain C1_1 PF00130.22 KFO95511.1 - 2.9e-12 46.3 8.5 5.6e-12 45.4 8.5 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 KFO95511.1 - 5.2e-07 29.3 0.0 7.8e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFO95511.1 - 9.9e-05 21.3 0.2 0.00017 20.5 0.2 1.5 1 1 0 1 1 1 1 Fungal protein kinase zf-RING-like PF08746.11 KFO95511.1 - 0.00024 21.4 4.4 0.00077 19.7 4.4 1.9 1 0 0 1 1 1 1 RING-like domain C1_2 PF03107.16 KFO95511.1 - 0.036 14.4 4.0 0.073 13.4 4.0 1.5 1 0 0 1 1 1 0 C1 domain Zf_RING PF16744.5 KFO95511.1 - 0.41 10.8 3.6 2.1 8.5 3.6 2.2 1 0 0 1 1 1 0 KIAA1045 RING finger zf-C3HC4_2 PF13923.6 KFO95511.1 - 0.91 9.4 10.1 0.19 11.6 5.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFO95511.1 - 6.4 7.2 12.5 0.46 10.9 7.2 1.9 2 0 0 2 2 2 0 Ring finger domain zf-CCHC PF00098.23 KFO95513.1 - 4.7e-53 175.0 63.9 3.3e-08 33.3 2.1 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_5 PF14787.6 KFO95513.1 - 3.8e-16 58.5 47.7 0.0004 20.0 1.7 7.1 5 1 2 7 7 7 6 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 KFO95513.1 - 7e-13 48.1 46.8 0.02 14.6 0.6 7.1 6 1 1 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 KFO95513.1 - 1.7e-08 34.2 48.6 0.0024 17.8 0.3 7.0 2 1 5 7 7 7 6 Zinc knuckle zf-CCHC_2 PF13696.6 KFO95513.1 - 0.0003 20.5 58.1 0.0037 17.0 1.4 7.2 7 0 0 7 7 7 5 Zinc knuckle Isy1 PF06246.12 KFO95514.1 - 2.2e-68 230.6 8.2 2.5e-68 230.4 8.2 1.0 1 0 0 1 1 1 1 Isy1-like splicing family Ebp2 PF05890.12 KFO95514.1 - 0.042 13.4 5.6 0.058 12.9 5.6 1.2 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 DUF4637 PF15470.6 KFO95514.1 - 3.2 7.4 8.7 4.6 7.0 8.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CDC45 PF02724.14 KFO95514.1 - 7.8 4.7 9.5 9.8 4.3 9.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Hydrolase_6 PF13344.6 KFO95515.1 - 1.6e-22 79.5 0.0 3.6e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFO95515.1 - 6.1e-07 29.4 0.0 1.5e-05 24.9 0.0 2.8 1 1 0 1 1 1 1 HAD-hyrolase-like Ras PF00071.22 KFO95516.1 - 4.9e-36 123.8 0.1 6e-36 123.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO95516.1 - 1.1e-17 64.4 0.0 2.2e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO95516.1 - 2.7e-06 26.9 0.1 3.3e-06 26.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF2786 PF10979.8 KFO95516.1 - 0.12 12.3 0.4 0.87 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) LMF1 PF06762.14 KFO95518.1 - 7e-143 476.9 13.7 7.7e-74 249.4 9.8 2.1 1 1 1 2 2 2 2 Lipase maturation factor AAA PF00004.29 KFO95522.1 - 7.4e-14 52.3 0.0 1.2e-13 51.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFO95522.1 - 5e-10 39.5 0.0 9.4e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFO95522.1 - 5.1e-08 32.8 0.0 7.9e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KFO95522.1 - 9.1e-08 32.2 0.1 2.1e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 KFO95522.1 - 1e-05 26.0 0.0 0.0048 17.3 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KFO95522.1 - 1.3e-05 25.2 0.0 2.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFO95522.1 - 1.6e-05 25.2 0.0 0.00042 20.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFO95522.1 - 0.00013 22.1 0.0 0.00029 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFO95522.1 - 0.00044 20.8 0.0 0.001 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFO95522.1 - 0.00083 19.1 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 KFO95522.1 - 0.00088 19.0 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KFO95522.1 - 0.0019 17.7 0.0 0.0093 15.5 0.0 2.0 2 1 1 3 3 3 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KFO95522.1 - 0.0046 16.9 0.0 0.0065 16.4 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 KFO95522.1 - 0.0052 16.7 0.0 0.16 11.9 0.0 2.3 1 1 1 2 2 2 1 NACHT domain AAA_25 PF13481.6 KFO95522.1 - 0.0056 16.3 0.1 0.018 14.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KFO95522.1 - 0.0067 15.7 0.0 0.0097 15.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.11 KFO95522.1 - 0.0092 15.8 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KFO95522.1 - 0.011 15.6 0.3 0.21 11.5 0.0 2.2 1 1 0 2 2 2 0 NTPase NB-ARC PF00931.22 KFO95522.1 - 0.011 14.9 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 KFO95522.1 - 0.012 16.1 0.0 0.036 14.6 0.0 1.6 1 1 1 2 2 1 0 ABC transporter TniB PF05621.11 KFO95522.1 - 0.014 14.8 0.0 0.26 10.7 0.0 2.1 1 1 1 2 2 2 0 Bacterial TniB protein AAA_28 PF13521.6 KFO95522.1 - 0.016 15.5 0.8 0.07 13.4 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 KFO95522.1 - 0.021 14.6 0.0 0.045 13.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 KFO95522.1 - 0.024 13.8 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_17 PF13207.6 KFO95522.1 - 0.026 14.9 0.0 0.048 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KFO95522.1 - 0.033 14.2 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 KFO95522.1 - 0.034 14.5 0.2 0.15 12.4 0.2 2.0 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KFO95522.1 - 0.035 13.8 0.0 0.25 11.0 0.0 1.9 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.6 KFO95522.1 - 0.049 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NAD_binding_1 PF00175.21 KFO95522.1 - 0.079 13.6 0.0 0.87 10.3 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain RNA_helicase PF00910.22 KFO95522.1 - 0.082 13.3 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase SKI PF01202.22 KFO95522.1 - 0.16 12.1 0.3 2.3 8.3 0.0 2.4 2 1 0 2 2 2 0 Shikimate kinase PMC2NT PF08066.12 KFO95522.1 - 0.18 12.5 0.0 2.2 9.0 0.0 2.3 2 0 0 2 2 2 0 PMC2NT (NUC016) domain PseudoU_synth_2 PF00849.22 KFO95523.1 - 8.7e-25 87.7 0.0 1.1e-24 87.3 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase Mesothelin PF06060.12 KFO95525.1 - 6.6e-15 54.3 0.8 6.8e-15 54.3 0.8 1.0 1 0 0 1 1 1 1 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) Mesothelin PF06060.12 KFO95526.1 - 5.4e-137 457.6 0.0 6.6e-137 457.4 0.0 1.0 1 0 0 1 1 1 1 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) Fe_hyd_lg_C PF02906.14 KFO95528.1 - 6.4e-76 255.2 0.0 9.1e-76 254.7 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 KFO95528.1 - 2e-10 40.6 0.3 4.8e-10 39.4 0.0 1.8 2 0 0 2 2 2 1 Iron hydrogenase small subunit HAGH_C PF16123.5 KFO95529.1 - 2.9e-25 88.6 0.5 4.8e-25 87.9 0.5 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KFO95529.1 - 2.2e-08 34.3 1.6 1.5e-07 31.7 1.6 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFO95529.1 - 0.0002 21.0 0.2 0.00043 19.9 0.2 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain HAGH_C PF16123.5 KFO95530.1 - 1.6e-28 99.1 0.1 3.3e-28 98.0 0.1 1.6 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KFO95530.1 - 2.5e-11 44.0 0.6 7.7e-07 29.3 0.3 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFO95530.1 - 0.00057 19.5 0.1 0.0012 18.4 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain REPA_OB_2 PF16900.5 KFO95531.1 - 1.5e-07 31.2 0.3 6.6e-05 22.8 0.1 2.7 3 0 0 3 3 3 2 Replication protein A OB domain CDC24_OB3 PF17244.2 KFO95531.1 - 5.8e-06 26.2 0.3 7.5e-05 22.5 0.8 2.1 2 0 0 2 2 2 1 Cell division control protein 24, OB domain 3 Sulfotransfer_1 PF00685.27 KFO95532.1 - 9.1e-32 110.6 0.0 1.1e-31 110.3 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFO95532.1 - 9.4e-12 45.8 0.0 1.5e-11 45.1 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFO95532.1 - 0.011 15.7 0.0 0.043 13.7 0.0 1.8 2 0 0 2 2 2 0 Sulfotransferase family CAS_CSE1 PF03378.15 KFO95532.1 - 0.17 10.3 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus SelR PF01641.18 KFO95533.1 - 2e-16 60.2 0.0 2.2e-16 60.1 0.0 1.0 1 0 0 1 1 1 1 SelR domain Zn_ribbon_recom PF13408.6 KFO95533.1 - 0.0015 19.0 0.3 0.9 10.1 0.0 2.2 2 0 0 2 2 2 2 Recombinase zinc beta ribbon domain TF_Zn_Ribbon PF08271.12 KFO95533.1 - 0.029 13.9 0.2 6 6.5 0.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_2 PF13240.6 KFO95533.1 - 0.031 14.0 2.9 1.4 8.7 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf_UBZ PF18439.1 KFO95533.1 - 0.045 13.3 1.4 0.25 10.9 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn_ribbon_SprT PF17283.2 KFO95533.1 - 0.051 13.5 0.7 3.8 7.5 0.2 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain DUF983 PF06170.12 KFO95533.1 - 0.052 14.0 0.7 3.8 8.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) TFIIS_C PF01096.18 KFO95533.1 - 0.11 12.3 1.2 4 7.4 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.10 KFO95533.1 - 0.13 12.4 1.5 1.8 8.8 0.2 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 KFO95533.1 - 0.29 11.1 2.9 0.88 9.6 0.3 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.6 KFO95533.1 - 0.29 10.9 2.9 2.1 8.2 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.13 KFO95533.1 - 0.3 10.8 3.2 1.5 8.6 0.1 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-NADH-PPase PF09297.11 KFO95533.1 - 0.39 10.4 5.4 0.97 9.2 0.3 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Rubredoxin_2 PF18073.1 KFO95533.1 - 1.6 8.5 6.8 0.4 10.5 0.5 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain MMM1 PF10296.9 KFO95535.1 - 3.4e-08 32.9 0.0 6.6e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 Ribosomal_L3 PF00297.22 KFO95536.1 - 1.5e-180 600.0 13.0 1.7e-180 599.8 13.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 RTX PF02382.15 KFO95536.1 - 0.041 13.6 0.0 0.057 13.1 0.0 1.1 1 0 0 1 1 1 0 N-terminal domain in RTX protein NDUFB10 PF10249.9 KFO95537.1 - 7e-51 172.0 5.4 8.7e-51 171.7 5.4 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Rtt106_N PF18215.1 KFO95537.1 - 0.13 12.0 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 Histone chaperone Rtt106 N-terminal domain WW PF00397.26 KFO95537.1 - 0.19 11.9 2.9 0.2 11.8 0.7 2.1 2 0 0 2 2 2 0 WW domain Ribosomal_S5 PF00333.20 KFO95538.1 - 2.5e-31 107.4 0.4 4.9e-31 106.5 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KFO95538.1 - 6.9e-27 92.7 0.0 1.2e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain WD40 PF00400.32 KFO95539.1 - 8.6e-52 172.0 37.9 5.8e-06 26.9 0.0 10.5 10 0 0 10 10 10 9 WD domain, G-beta repeat Utp13 PF08625.11 KFO95539.1 - 1.8e-41 141.3 2.8 3e-41 140.6 2.8 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 KFO95539.1 - 2.1e-07 31.1 3.4 0.61 10.4 0.1 6.1 4 1 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFO95539.1 - 0.00099 17.9 11.4 2 7.0 0.6 5.8 4 2 2 6 6 6 2 Nucleoporin Nup120/160 UTP15_C PF09384.10 KFO95539.1 - 0.006 16.3 3.1 0.01 15.5 3.1 1.4 1 0 0 1 1 1 1 UTP15 C terminal Nucleoporin_N PF08801.11 KFO95539.1 - 0.0075 15.1 2.5 5.5 5.6 0.0 4.5 2 2 3 5 5 5 3 Nup133 N terminal like Mcl1_mid PF12341.8 KFO95539.1 - 0.033 13.5 0.0 0.71 9.2 0.0 2.7 2 0 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region LRRC37AB_C PF14914.6 KFO95539.1 - 0.035 14.0 0.7 0.069 13.1 0.7 1.5 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain MutL_C PF08676.11 KFO95539.1 - 0.07 12.9 0.2 0.17 11.6 0.2 1.6 1 0 0 1 1 1 0 MutL C terminal dimerisation domain SH3_9 PF14604.6 KFO95540.1 - 2.3e-15 56.2 0.1 6.8e-11 41.9 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KFO95540.1 - 2.8e-14 52.4 0.7 1.5e-09 37.3 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KFO95540.1 - 1.7e-11 43.6 0.0 1.3e-07 31.2 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 KFO95540.1 - 5.2e-10 39.3 0.7 3.8e-09 36.5 0.7 2.2 2 1 0 2 2 2 1 PX domain SH3_3 PF08239.11 KFO95540.1 - 1.4e-07 31.7 0.9 0.00065 19.9 0.1 2.6 2 0 0 2 2 2 2 Bacterial SH3 domain p47_phox_C PF08944.11 KFO95540.1 - 6.7e-07 28.6 1.4 1.3e-06 27.6 1.4 1.5 1 0 0 1 1 1 1 NADPH oxidase subunit p47Phox, C terminal domain SH3_4 PF06347.13 KFO95540.1 - 2.2e-06 27.4 0.1 8.6e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 Bacterial SH3 domain hSH3 PF14603.6 KFO95540.1 - 0.092 13.2 0.0 9.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Helically-extended SH3 domain HepII_C PF18675.1 KFO95540.1 - 0.14 12.2 0.2 2.2 8.4 0.2 2.3 1 1 0 1 1 1 0 Heparinase II C-terminal domain Evr1_Alr PF04777.13 KFO95541.1 - 3.1e-31 107.8 3.7 3.7e-31 107.6 3.7 1.1 1 0 0 1 1 1 1 Erv1 / Alr family DUF3970 PF13113.6 KFO95541.1 - 0.012 15.8 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3970) FAD_SOX PF18371.1 KFO95541.1 - 0.028 14.8 0.0 0.26 11.7 0.0 1.9 1 1 1 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase MARVEL PF01284.23 KFO95542.1 - 2.9e-24 85.7 12.1 3.8e-24 85.4 12.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain PEN-2 PF10251.9 KFO95542.1 - 0.44 11.0 4.6 0.31 11.5 2.4 1.8 1 1 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase DUF2897 PF11446.8 KFO95542.1 - 0.54 10.2 0.0 0.54 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) HRG PF16954.5 KFO95542.1 - 1.5 9.2 13.9 4.3 7.8 0.4 2.8 2 1 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene zf-C2H2_4 PF13894.6 KFO95543.1 - 0.0042 17.8 30.6 0.043 14.6 0.2 6.6 5 1 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KFO95543.1 - 0.0076 16.6 0.6 0.0076 16.6 0.6 5.9 6 0 0 6 6 6 4 Zinc finger, C2H2 type EBP50_C PF09007.11 KFO95544.1 - 5.9e-30 104.9 6.2 3.5e-27 96.0 4.9 2.8 2 1 0 2 2 2 1 EBP50, C-terminal PDZ_6 PF17820.1 KFO95544.1 - 6.4e-16 57.9 1.6 6.5e-16 57.9 0.1 1.8 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 KFO95544.1 - 2.9e-14 53.2 0.0 1.3e-13 51.0 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KFO95544.1 - 2e-06 28.0 0.0 8.6e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 PDZ domain GRASP55_65 PF04495.14 KFO95544.1 - 0.14 12.5 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain HhH-GPD PF00730.25 KFO95545.1 - 3.3e-20 72.5 0.0 4.5e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KFO95545.1 - 1.3e-09 37.4 0.0 2.5e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KFO95545.1 - 0.039 14.6 0.0 0.51 11.0 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain Cdd1 PF11731.8 KFO95545.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Pathogenicity locus Tuberin PF03542.16 KFO95546.1 - 4.7e-145 483.1 4.4 4.7e-145 483.1 4.4 3.2 3 0 0 3 3 3 2 Tuberin DUF3384 PF11864.8 KFO95546.1 - 1e-95 321.5 9.5 1e-95 321.5 9.5 3.3 4 1 0 4 4 4 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 KFO95546.1 - 4.7e-42 143.6 0.0 9.3e-42 142.7 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Cnd1 PF12717.7 KFO95546.1 - 0.037 14.1 3.8 0.041 13.9 0.2 3.0 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFO95546.1 - 0.095 13.0 0.6 2.7 8.5 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat PKD PF00801.20 KFO95547.1 - 1.1e-167 544.2 93.4 2.1e-17 62.7 1.3 16.9 18 0 0 18 18 18 15 PKD domain REJ PF02010.15 KFO95547.1 - 1.1e-105 354.1 0.8 1e-104 350.9 0.0 2.8 3 0 0 3 3 3 1 REJ domain PKD_channel PF08016.12 KFO95547.1 - 8.3e-90 301.5 14.1 1.3e-89 300.9 14.1 1.3 1 0 0 1 1 1 1 Polycystin cation channel PLAT PF01477.23 KFO95547.1 - 1.5e-21 77.1 0.1 6.4e-21 75.1 0.1 2.2 1 0 0 1 1 1 1 PLAT/LH2 domain Lectin_C PF00059.21 KFO95547.1 - 1.4e-11 45.1 2.2 3.2e-11 43.9 0.3 2.5 2 0 0 2 2 2 1 Lectin C-type domain Y_Y_Y PF07495.13 KFO95547.1 - 1.1e-08 34.9 11.0 0.2 11.6 0.0 7.0 7 0 0 7 7 7 3 Y_Y_Y domain LRR_8 PF13855.6 KFO95547.1 - 2.8e-08 33.4 4.6 7.8e-08 32.0 4.6 1.8 1 0 0 1 1 1 1 Leucine rich repeat WSC PF01822.19 KFO95547.1 - 4.9e-06 26.7 6.9 1.2e-05 25.4 6.9 1.7 1 0 0 1 1 1 1 WSC domain GPS PF01825.21 KFO95547.1 - 0.015 15.8 1.8 0.025 15.1 0.0 2.5 2 0 0 2 2 1 0 GPCR proteolysis site, GPS, motif LRR_4 PF12799.7 KFO95547.1 - 0.021 15.3 2.1 0.1 13.0 2.1 2.3 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) LRRCT PF01463.24 KFO95547.1 - 0.11 13.1 0.0 0.36 11.5 0.0 2.0 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain DUF1727 PF08353.10 KFO95547.1 - 0.18 11.7 0.0 41 4.2 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1727) Ras PF00071.22 KFO95548.1 - 1.6e-59 200.2 0.2 1.8e-59 200.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO95548.1 - 2e-33 115.2 0.1 2.9e-33 114.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO95548.1 - 4.1e-14 52.4 0.1 4.6e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFO95548.1 - 5.9e-06 25.8 0.1 7.8e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFO95548.1 - 0.0002 21.4 0.0 0.00034 20.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFO95548.1 - 0.00031 20.7 0.7 0.49 10.3 0.1 2.3 2 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFO95548.1 - 0.00072 19.1 0.3 0.0017 17.9 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KFO95548.1 - 0.00082 18.9 0.1 0.0037 16.8 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 KFO95548.1 - 0.0052 16.2 0.0 0.0058 16.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KFO95548.1 - 0.014 15.8 0.1 0.029 14.8 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AsnC_trans_reg2 PF17805.1 KFO95548.1 - 0.019 15.1 0.2 0.066 13.4 0.1 1.8 2 0 0 2 2 2 0 AsnC-like ligand binding domain Septin PF00735.18 KFO95548.1 - 0.023 14.0 0.2 0.06 12.6 0.2 1.7 1 1 0 1 1 1 0 Septin AAA_22 PF13401.6 KFO95548.1 - 0.049 13.9 0.1 0.18 12.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KFO95548.1 - 0.07 13.6 0.1 0.94 9.9 0.0 2.5 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 KFO95548.1 - 0.13 12.1 0.0 0.21 11.3 0.0 1.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 KFO95548.1 - 0.14 12.1 0.1 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 NACHT domain WD40 PF00400.32 KFO95549.1 - 1.1e-31 108.3 21.8 4.6e-08 33.6 1.2 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat WD40_like PF17005.5 KFO95549.1 - 3.1e-08 33.3 1.3 5.9e-08 32.4 1.3 1.4 1 0 0 1 1 1 1 WD40-like domain Sina PF03145.16 KFO95549.1 - 7.9e-06 26.0 5.7 0.0024 17.8 0.9 2.4 2 0 0 2 2 2 2 Seven in absentia protein family zf-RING_UBOX PF13445.6 KFO95549.1 - 9.2e-06 25.6 8.4 9.2e-06 25.6 8.4 2.5 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFO95549.1 - 4.2e-05 23.3 14.3 4.2e-05 23.3 14.3 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFO95549.1 - 4.6e-05 23.2 10.3 4.6e-05 23.2 10.3 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFO95549.1 - 5.9e-05 23.1 7.3 0.00023 21.3 7.3 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KFO95549.1 - 0.00013 21.8 11.4 0.00057 19.7 11.4 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PKcGMP_CC PF16808.5 KFO95549.1 - 0.00038 20.2 0.6 0.0026 17.5 0.0 2.4 2 0 0 2 2 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Nup160 PF11715.8 KFO95549.1 - 0.00059 18.6 6.7 0.0032 16.2 0.5 3.7 3 1 1 4 4 4 1 Nucleoporin Nup120/160 zf-RING_5 PF14634.6 KFO95549.1 - 0.0086 16.0 13.3 0.0086 16.0 13.3 2.4 2 0 0 2 2 1 1 zinc-RING finger domain Nucleoporin_N PF08801.11 KFO95549.1 - 0.014 14.2 0.9 1.2 7.8 0.0 3.4 1 1 1 3 3 3 0 Nup133 N terminal like DUF16 PF01519.16 KFO95549.1 - 0.037 14.5 0.1 0.074 13.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 PQQ_3 PF13570.6 KFO95549.1 - 0.075 13.5 2.3 21 5.8 0.1 4.8 5 1 0 5 5 4 0 PQQ-like domain KxDL PF10241.9 KFO95549.1 - 0.082 13.2 1.3 0.17 12.2 1.3 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF641 PF04859.12 KFO95549.1 - 0.096 13.0 0.1 0.17 12.3 0.1 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) zf-RING_10 PF16685.5 KFO95549.1 - 0.48 10.6 10.4 1.8 8.8 10.4 2.0 1 0 0 1 1 1 0 zinc RING finger of MSL2 HSBP1 PF06825.12 KFO95549.1 - 0.49 10.3 4.1 3.5 7.6 4.1 2.1 1 1 0 1 1 1 0 Heat shock factor binding protein 1 Prok-RING_4 PF14447.6 KFO95549.1 - 0.92 9.4 15.0 0.053 13.4 8.5 2.4 2 0 0 2 2 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KFO95549.1 - 7 6.6 11.7 2.3 8.1 7.3 2.5 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Glyco_hydro_20 PF00728.22 KFO95550.1 - 1.3e-10 41.2 0.0 2.3e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain WD40 PF00400.32 KFO95552.1 - 2.7e-23 81.8 4.7 2.3e-05 25.0 0.0 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO95552.1 - 2.2e-09 37.5 0.2 0.00033 20.9 0.1 3.4 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 KFO95552.1 - 0.00098 18.9 0.4 0.084 12.6 0.0 2.6 1 1 2 3 3 3 2 TUP1-like enhancer of split Ge1_WD40 PF16529.5 KFO95552.1 - 0.002 17.2 0.1 0.78 8.6 0.0 3.1 1 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFO95552.1 - 0.028 13.1 1.3 6.3 5.3 0.0 3.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DUF2415 PF10313.9 KFO95552.1 - 0.055 13.4 0.1 4.3 7.3 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Frtz PF11768.8 KFO95552.1 - 0.16 10.2 0.1 0.2 9.9 0.1 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz BRICHOS PF04089.14 KFO95553.1 - 6.1e-20 71.3 0.1 9.8e-20 70.6 0.1 1.3 1 0 0 1 1 1 1 BRICHOS domain ISN1 PF06437.11 KFO95553.1 - 0.12 11.2 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase RhoGAP PF00620.27 KFO95554.1 - 9.9e-46 155.3 0.0 1.1e-44 151.9 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain BAR PF03114.18 KFO95554.1 - 7.6e-25 87.9 1.0 7.6e-25 87.9 1.0 1.6 2 0 0 2 2 2 1 BAR domain Hydrolase_like PF13242.6 KFO95554.1 - 1e-17 64.0 0.0 2e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 KFO95554.1 - 0.00025 21.2 0.0 0.0052 16.9 0.0 2.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFO95554.1 - 0.00049 20.5 0.1 0.0029 17.9 0.0 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KFO95554.1 - 0.0021 17.7 0.1 0.0059 16.2 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase APP_E2 PF12925.7 KFO95554.1 - 0.11 12.2 4.4 6.1 6.5 0.9 3.2 2 1 1 3 3 3 0 E2 domain of amyloid precursor protein zf-C2H2 PF00096.26 KFO95555.1 - 3.8e-41 137.3 63.1 6e-05 23.3 3.2 10.5 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO95555.1 - 3.4e-35 118.9 73.7 4.5e-08 33.2 1.7 10.4 11 0 0 11 11 10 9 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFO95555.1 - 1.1e-34 116.0 62.9 0.00081 20.0 2.0 10.5 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO95555.1 - 3.8e-22 78.0 29.7 0.00025 21.3 0.3 10.3 10 0 0 10 10 10 7 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFO95555.1 - 1e-08 34.8 37.0 0.001 18.8 0.1 9.1 10 0 0 10 10 10 4 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFO95555.1 - 1.9e-07 30.9 64.3 0.076 13.0 1.1 10.1 10 0 0 10 10 10 5 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFO95555.1 - 3.7e-05 23.7 51.6 0.044 13.9 1.9 8.8 7 3 3 10 10 10 4 Zinc ribbon domain zf_UBZ PF18439.1 KFO95555.1 - 0.00026 20.5 36.0 0.46 10.1 0.1 9.4 10 0 0 10 10 10 4 Ubiquitin-Binding Zinc Finger Zn-C2H2_12 PF18112.1 KFO95555.1 - 0.00076 19.9 7.2 2.3 8.7 0.1 5.1 4 0 0 4 4 4 2 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_8 PF15909.5 KFO95555.1 - 0.0011 19.2 34.5 0.042 14.1 0.9 5.9 3 2 3 6 6 6 4 C2H2-type zinc ribbon zf-met PF12874.7 KFO95555.1 - 0.0012 19.2 0.6 0.0012 19.2 0.6 8.9 10 0 0 10 10 10 2 Zinc-finger of C2H2 type XPA_N PF01286.18 KFO95555.1 - 0.023 14.7 0.3 0.023 14.7 0.3 7.4 10 0 0 10 10 9 0 XPA protein N-terminal zf-C2H2_2 PF12756.7 KFO95555.1 - 0.023 15.0 43.7 0.22 11.9 0.4 8.5 3 2 6 9 9 9 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KFO95555.1 - 0.034 14.0 40.5 0.22 11.5 2.2 7.9 8 0 0 8 8 8 0 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 KFO95555.1 - 0.086 13.6 36.1 1.3 9.8 0.2 5.9 4 2 2 7 7 7 0 zinc-ribbon family ADK_lid PF05191.14 KFO95555.1 - 0.13 12.3 31.7 1.1 9.4 0.4 6.7 5 2 1 6 6 6 0 Adenylate kinase, active site lid DUF3268 PF11672.8 KFO95555.1 - 0.35 11.2 19.2 1.2 9.4 1.3 4.4 3 2 0 4 4 4 0 zinc-finger-containing domain DZR PF12773.7 KFO95555.1 - 1.7 8.7 41.2 2.6 8.1 4.8 6.1 3 2 0 3 3 3 0 Double zinc ribbon zf-Di19 PF05605.12 KFO95555.1 - 3.3 8.1 37.2 0.12 12.7 2.0 6.7 4 2 3 8 8 8 0 Drought induced 19 protein (Di19), zinc-binding zf-MYST PF17772.1 KFO95555.1 - 4.2 7.0 18.9 3.3 7.4 0.1 5.3 6 0 0 6 6 6 0 MYST family zinc finger domain Zn_Tnp_IS1595 PF12760.7 KFO95555.1 - 4.6 7.3 46.3 1.9 8.5 0.2 7.0 5 2 0 5 5 4 0 Transposase zinc-ribbon domain zinc_ribbon_9 PF14369.6 KFO95555.1 - 8.6 6.7 23.7 9.2 6.6 0.0 7.1 7 0 0 7 7 7 0 zinc-ribbon FH2 PF02181.23 KFO95556.1 - 2.4e-92 309.9 9.5 3.2e-92 309.5 9.5 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain PDZ PF00595.24 KFO95556.1 - 3e-13 49.9 0.0 5.5e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFO95556.1 - 5.5e-08 32.5 0.0 1.4e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFO95556.1 - 0.00088 19.6 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain SSF PF00474.17 KFO95557.1 - 3.1e-144 480.8 20.2 4.1e-144 480.4 20.2 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family TMCCDC2 PF15844.5 KFO95557.1 - 0.048 13.6 0.2 0.41 10.6 0.0 2.6 3 0 0 3 3 3 0 Transmembrane and coiled-coil domain-containing protein 2 BLUF PF04940.12 KFO95558.1 - 0.017 15.2 0.0 0.039 14.1 0.0 1.6 1 1 0 1 1 1 0 Sensors of blue-light using FAD Secapin PF17521.2 KFO95558.1 - 0.075 12.8 0.7 0.16 11.8 0.7 1.5 1 0 0 1 1 1 0 Honey bee peptides LCM PF04072.14 KFO95559.1 - 1.7e-38 132.5 0.0 2.2e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase MIP PF00230.20 KFO95560.1 - 0.0002 21.1 0.0 0.00022 21.0 0.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Pkinase PF00069.25 KFO95561.1 - 1.1e-61 208.5 0.0 1.5e-61 208.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO95561.1 - 5e-38 130.9 0.0 7.2e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 KFO95561.1 - 3.5e-27 94.7 0.1 5.6e-27 94.0 0.1 1.3 1 0 0 1 1 1 1 C2 domain C1_1 PF00130.22 KFO95561.1 - 2.8e-19 68.8 17.0 1.4e-17 63.3 5.8 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KFO95561.1 - 0.00015 22.4 1.5 0.00035 21.2 1.5 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFO95561.1 - 0.007 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFO95561.1 - 0.025 13.5 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain CEP76-C2 PF15627.6 KFO95561.1 - 0.036 13.6 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 CEP76 C2 domain APH PF01636.23 KFO95561.1 - 0.052 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_C PF00433.24 KFO95562.1 - 5.8e-11 42.9 1.5 7.3e-11 42.6 1.5 1.2 1 0 0 1 1 1 1 Protein kinase C terminal domain PMP22_Claudin PF00822.20 KFO95563.1 - 3.3e-33 114.9 0.6 4.6e-33 114.4 0.6 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFO95563.1 - 4.6e-09 36.3 0.5 8.4e-09 35.5 0.6 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DWNN PF08783.11 KFO95564.1 - 1.5e-30 105.3 1.9 3.2e-30 104.2 0.1 2.5 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.6 KFO95564.1 - 2.7e-09 36.7 6.8 2.7e-09 36.7 6.8 1.8 2 0 0 2 2 1 1 Zinc knuckle U-box PF04564.15 KFO95564.1 - 4e-07 30.1 0.0 1.2e-06 28.5 0.0 1.9 1 0 0 1 1 1 1 U-box domain zf-C3HC4_2 PF13923.6 KFO95564.1 - 1.5e-05 24.7 11.3 1.5e-05 24.7 11.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC PF00098.23 KFO95564.1 - 2.1e-05 24.4 2.7 4.9e-05 23.2 2.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_3 PF13920.6 KFO95564.1 - 4.6e-05 23.2 9.7 4.6e-05 23.2 9.7 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFO95564.1 - 0.0014 18.6 11.0 0.0034 17.3 11.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFO95564.1 - 0.0029 17.9 11.7 0.0057 17.0 11.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KFO95564.1 - 0.015 15.4 11.9 0.041 14.0 11.9 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KFO95564.1 - 0.017 15.0 12.2 0.036 13.9 12.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFO95564.1 - 0.19 11.8 10.2 0.45 10.6 10.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.6 KFO95564.1 - 0.39 10.6 4.5 0.79 9.6 4.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 KFO95564.1 - 0.43 10.5 10.2 0.92 9.4 10.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DZR PF12773.7 KFO95564.1 - 2.6 8.2 9.2 2.6 8.2 4.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon TNRC6-PABC_bdg PF16608.5 KFO95565.1 - 1.8e-121 405.4 33.3 1.8e-121 405.4 33.3 6.7 6 1 0 6 6 6 1 TNRC6-PABC binding domain Ago_hook PF10427.9 KFO95565.1 - 1.1e-14 55.3 20.6 1.1e-14 55.3 20.6 10.9 3 2 7 10 10 10 1 Argonaute hook RRM_1 PF00076.22 KFO95565.1 - 0.0012 18.6 0.0 0.0032 17.2 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PP-binding PF00550.25 KFO95566.1 - 9.6e-13 48.3 0.1 1.2e-12 48.0 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KFO95566.1 - 0.0008 19.6 0.2 0.00092 19.4 0.2 1.1 1 0 0 1 1 1 1 Acyl-carrier PALB2_WD40 PF16756.5 KFO95567.1 - 6.5e-147 489.0 0.0 9.3e-147 488.5 0.0 1.2 1 0 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain Hexapep PF00132.24 KFO95568.1 - 6.7e-16 57.3 22.7 4.7e-06 26.1 2.9 4.3 3 1 2 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFO95568.1 - 0.00013 21.6 9.5 0.0042 16.8 0.5 3.9 3 2 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KFO95568.1 - 0.0077 14.4 0.3 0.0092 14.2 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 KFO95568.1 - 0.038 12.9 1.7 0.083 11.8 1.3 1.7 1 1 1 2 2 2 0 L-fucokinase Ribonuc_2-5A PF06479.12 KFO95569.1 - 4.9e-41 139.9 0.0 8.6e-41 139.1 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 KFO95569.1 - 2.3e-39 135.4 0.0 3.1e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO95569.1 - 2.8e-23 82.5 0.0 4.2e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 KFO95569.1 - 2.4e-08 33.5 0.2 0.0047 16.8 0.0 3.2 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_2 PF13360.6 KFO95569.1 - 1.8e-07 31.0 0.0 0.0013 18.4 0.0 2.6 2 1 0 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 KFO95569.1 - 0.0018 18.7 1.0 31 5.2 0.0 5.6 5 0 0 5 5 5 0 PQQ-like domain Pkinase_fungal PF17667.1 KFO95569.1 - 0.0044 15.8 0.0 0.0064 15.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFO95569.1 - 0.0055 16.1 0.0 0.0093 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFO95569.1 - 0.0081 16.1 1.3 0.7 9.8 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family ubiquitin PF00240.23 KFO95570.1 - 3.8e-12 45.8 0.0 7.7e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KFO95570.1 - 0.0026 18.2 0.0 0.02 15.3 0.0 2.3 1 1 1 2 2 2 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KFO95570.1 - 0.007 16.7 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain tRNA-synt_1c PF00749.21 KFO95571.1 - 1.5e-81 273.8 0.0 2.5e-81 273.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain VHS PF00790.19 KFO95572.1 - 6.3e-45 152.5 0.8 1.4e-43 148.1 0.0 2.6 3 0 0 3 3 3 1 VHS domain GGA_N-GAT PF18308.1 KFO95572.1 - 1.5e-17 62.9 4.4 1.5e-17 62.9 4.4 2.8 3 0 0 3 3 3 1 GGA N-GAT domain GAT PF03127.14 KFO95572.1 - 7.8e-17 61.4 3.5 7.8e-17 61.4 3.5 2.4 2 0 0 2 2 2 1 GAT domain DUF2959 PF11172.8 KFO95572.1 - 0.018 15.2 3.1 0.033 14.3 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) Flagellin_N PF00669.20 KFO95572.1 - 0.043 13.9 1.5 0.084 13.0 1.5 1.4 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region DUF4874 PF16173.5 KFO95572.1 - 0.05 13.3 1.0 0.11 12.2 0.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4874) DUF3837 PF12939.7 KFO95572.1 - 0.13 12.6 1.4 0.42 11.0 1.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3837) PCRF PF03462.18 KFO95572.1 - 0.23 11.3 4.6 0.45 10.3 4.6 1.5 1 0 0 1 1 1 0 PCRF domain COG7 PF10191.9 KFO95573.1 - 0 1081.9 17.7 0 1081.7 17.7 1.0 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) COG5 PF10392.9 KFO95573.1 - 0.0009 19.4 9.4 0.0025 18.0 1.2 3.3 2 1 1 3 3 3 2 Golgi transport complex subunit 5 FlgN PF05130.12 KFO95573.1 - 0.42 11.1 9.7 11 6.5 4.9 3.3 2 1 0 2 2 2 0 FlgN protein zf-C4H2 PF10146.9 KFO95573.1 - 3.8 7.8 5.6 10 6.4 5.6 1.7 1 0 0 1 1 1 0 Zinc finger-containing protein ASC PF00858.24 KFO95574.1 - 6.6e-112 374.7 7.6 1.9e-111 373.2 7.6 1.6 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel Toxin_TOLIP PF00087.21 KFO95574.1 - 0.0024 18.1 2.3 0.0083 16.4 2.3 1.9 1 0 0 1 1 1 1 Snake toxin and toxin-like protein ASC PF00858.24 KFO95575.1 - 5.8e-101 338.6 10.9 6.8e-101 338.4 10.9 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel UCH PF00443.29 KFO95576.1 - 6.6e-39 134.0 0.0 2.7e-38 131.9 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFO95576.1 - 7.5e-11 42.2 0.1 9.6e-06 25.4 0.2 2.7 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zinc_ribbon_10 PF10058.9 KFO95576.1 - 0.026 14.2 0.4 13 5.6 0.0 2.8 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn_Tnp_IS1595 PF12760.7 KFO95576.1 - 0.23 11.5 3.2 9.8 6.2 0.0 3.2 3 0 0 3 3 3 0 Transposase zinc-ribbon domain zf-MIZ PF02891.20 KFO95576.1 - 3.4 7.5 9.3 1.5 8.6 5.2 2.5 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Sulfotransfer_1 PF00685.27 KFO95577.1 - 3.2e-35 121.9 0.0 3.6e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFO95577.1 - 1.4e-11 45.2 0.0 2.1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFO95577.1 - 0.011 15.7 0.1 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 Sulfotransferase family CNOT1_HEAT PF16418.5 KFO95578.1 - 0.03 14.4 0.0 0.03 14.4 0.0 1.0 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Sulfotransfer_1 PF00685.27 KFO95579.1 - 1.9e-45 155.4 0.0 2.3e-45 155.2 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFO95579.1 - 6.8e-16 59.3 0.0 1.8e-10 41.6 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFO95579.1 - 0.0047 16.9 0.0 0.056 13.3 0.0 2.1 2 0 0 2 2 2 1 Sulfotransferase family Cupin_8 PF13621.6 KFO95580.1 - 7e-46 157.0 0.2 8.7e-46 156.7 0.2 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KFO95580.1 - 2.1e-07 30.7 0.1 7.1e-07 29.0 0.1 1.7 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 KFO95580.1 - 0.018 15.5 0.1 0.074 13.5 0.1 2.0 1 1 0 1 1 1 0 JmjC domain, hydroxylase SMC_Nse1 PF07574.13 KFO95581.1 - 4.1e-27 95.3 0.6 5.9e-25 88.3 0.6 2.1 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KFO95581.1 - 1.2e-09 38.3 9.6 1.2e-09 38.3 9.6 2.5 3 0 0 3 3 3 1 RING-like domain zf-RING_2 PF13639.6 KFO95581.1 - 0.0061 16.9 9.5 0.0061 16.9 9.5 2.2 3 0 0 3 3 3 1 Ring finger domain Zn_ribbon_17 PF17120.5 KFO95581.1 - 0.01 15.4 6.5 0.025 14.2 6.5 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 KFO95581.1 - 0.023 14.6 9.8 0.023 14.6 9.8 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.6 KFO95581.1 - 0.16 11.4 6.9 0.23 10.9 1.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_2 PF13923.6 KFO95581.1 - 0.32 10.9 9.9 0.81 9.6 9.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IL4Ra_N PF09238.10 KFO95582.1 - 1.1e-29 102.6 2.4 1.1e-29 102.6 2.4 2.3 3 1 0 3 3 3 1 Interleukin-4 receptor alpha chain, N-terminal IL6Ra-bind PF09240.10 KFO95582.1 - 3.3e-06 27.4 1.0 6.7e-06 26.4 1.0 1.5 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.10 KFO95582.1 - 8.8e-05 22.7 1.7 0.00026 21.2 1.7 1.9 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding fn3 PF00041.21 KFO95582.1 - 0.0031 17.8 0.5 0.021 15.2 0.3 2.2 2 0 0 2 2 2 1 Fibronectin type III domain ObR_Ig PF18589.1 KFO95582.1 - 0.069 13.6 1.6 0.24 11.8 1.6 1.9 1 1 0 1 1 1 0 Obesity receptor immunoglobulin like domain IL2RB_N1 PF18707.1 KFO95582.1 - 0.92 10.1 5.8 0.63 10.6 1.0 2.4 2 1 0 2 2 2 0 Interleukin-2 receptor subunit beta N-terminal domain 1 EpoR_lig-bind PF09067.10 KFO95583.1 - 0.0015 18.7 3.4 0.0015 18.7 1.5 2.0 2 0 0 2 2 2 1 Erythropoietin receptor, ligand binding fn3 PF00041.21 KFO95583.1 - 0.023 15.1 0.2 0.071 13.5 0.2 1.8 1 0 0 1 1 1 0 Fibronectin type III domain LRR19-TM PF15176.6 KFO95583.1 - 0.22 11.5 0.8 0.57 10.2 0.8 1.7 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Pur_ac_phosph_N PF16656.5 KFO95583.1 - 0.23 12.1 2.5 0.35 11.5 1.1 2.0 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain IL4Ra_N PF09238.10 KFO95583.1 - 6.8 7.1 10.3 3.6 8.0 2.2 3.4 3 0 0 3 3 3 0 Interleukin-4 receptor alpha chain, N-terminal Pkinase PF00069.25 KFO95585.1 - 1.3e-66 224.7 0.0 1.5e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO95585.1 - 1.9e-34 119.1 0.0 2.7e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.6 KFO95585.1 - 5.9e-29 100.2 0.0 1.1e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 KFO95585.1 - 1e-06 28.3 0.0 1.8e-06 27.5 0.0 1.4 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFO95585.1 - 1.3e-05 24.2 0.1 1.6e-05 23.9 0.1 1.3 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFO95585.1 - 2.8e-05 23.3 0.1 4.3e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KFO95585.1 - 0.0015 18.2 0.0 1.8 8.1 0.0 2.3 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KFO95585.1 - 0.0065 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFO95585.1 - 0.013 15.5 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family BTB_2 PF02214.22 KFO95586.1 - 3.7e-11 43.2 0.0 6.1e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KFO95586.1 - 0.025 14.8 0.0 0.041 14.1 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain zf-RING_9 PF13901.6 KFO95586.1 - 0.062 13.3 0.0 0.079 12.9 0.0 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon SAM_LFY PF01698.16 KFO95586.1 - 0.094 12.7 0.1 0.17 11.8 0.0 1.4 1 1 0 1 1 1 0 Floricaula / Leafy protein SAM domain UQ_con PF00179.26 KFO95587.1 - 2e-49 166.8 0.0 2.3e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFO95587.1 - 4.1e-05 23.3 0.0 4.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Ribo_biogen_C PF04034.13 KFO95588.1 - 4.3e-54 181.6 0.0 5.5e-54 181.3 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KFO95588.1 - 2e-12 46.7 1.1 3.6e-12 45.9 1.1 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI PRKCSH_1 PF13015.6 KFO95589.1 - 7e-10 38.8 0.1 4.2e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KFO95589.1 - 1.8e-07 32.0 3.0 1.8e-07 32.0 3.0 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Ribosomal_L30_N PF08079.12 KFO95589.1 - 0.12 12.7 2.1 0.19 12.0 2.1 1.3 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain VP_N-CPKC PF11475.8 KFO95589.1 - 0.19 11.6 1.6 0.88 9.5 0.1 2.6 2 0 0 2 2 2 0 Virion protein N terminal domain zf_CCCH_5 PF18384.1 KFO95590.1 - 1.5e-20 73.0 16.6 1.5e-20 73.0 16.6 2.9 2 1 0 2 2 2 1 Unkempt Zinc finger domain 1 (Znf1) zf-C3HC4_3 PF13920.6 KFO95590.1 - 3.9e-09 36.2 11.9 3.9e-09 36.2 11.9 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.24 KFO95590.1 - 7.7e-06 25.7 2.2 7.7e-06 25.7 2.2 6.8 6 0 0 6 6 6 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Prok-RING_4 PF14447.6 KFO95590.1 - 0.00073 19.3 12.1 0.00073 19.3 12.1 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Filament PF00038.21 KFO95590.1 - 0.0036 16.9 5.7 0.0036 16.9 5.7 1.5 2 0 0 2 2 2 1 Intermediate filament protein Golgin_A5 PF09787.9 KFO95590.1 - 0.047 13.2 3.3 0.093 12.2 3.3 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 MAD PF05557.13 KFO95590.1 - 0.13 10.6 8.0 0.2 9.9 8.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF3584 PF12128.8 KFO95590.1 - 0.45 8.0 7.7 0.72 7.3 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SPT16 PF08644.11 KFO95590.1 - 0.69 10.1 2.9 1.4 9.1 2.9 1.4 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) PCRF PF03462.18 KFO95590.1 - 0.95 9.3 4.5 2 8.2 4.5 1.5 1 0 0 1 1 1 0 PCRF domain DUF3560 PF12083.8 KFO95590.1 - 1 9.5 6.2 2.4 8.3 6.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) zf_CCCH_4 PF18345.1 KFO95590.1 - 3.6 7.8 30.5 0.061 13.4 0.9 6.4 5 1 0 5 5 5 0 Zinc finger domain Sulfotransfer_1 PF00685.27 KFO95593.1 - 5.8e-26 91.5 0.4 7.9e-26 91.1 0.4 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFO95593.1 - 3.5e-17 63.5 1.0 8.8e-10 39.3 0.0 3.1 2 1 1 3 3 3 2 Sulfotransferase family TM231 PF10149.9 KFO95594.1 - 1.3e-117 392.5 0.6 1.4e-117 392.3 0.6 1.0 1 0 0 1 1 1 1 Transmembrane protein 231 A_deamin PF02137.18 KFO95595.1 - 4.1e-119 397.9 0.3 8.4e-119 396.9 0.3 1.5 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain Dak1 PF02733.17 KFO95595.1 - 0.052 12.4 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Dak1 domain tRNA-synt_2 PF00152.20 KFO95596.1 - 6.5e-79 265.3 0.3 8.6e-79 264.9 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFO95596.1 - 1.4e-16 60.2 0.0 6.8e-16 58.0 0.0 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KFO95596.1 - 1.5e-07 31.1 0.1 0.0053 16.3 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) Sulfotransfer_1 PF00685.27 KFO95597.1 - 8.7e-28 97.5 0.1 1.2e-27 97.0 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFO95597.1 - 4.3e-17 63.2 0.7 6.7e-10 39.7 0.0 2.8 2 1 0 2 2 2 2 Sulfotransferase family Aminotran_1_2 PF00155.21 KFO95598.1 - 6.7e-73 245.9 0.0 7.8e-73 245.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II TAT_ubiq PF07706.12 KFO95598.1 - 2.8e-17 62.6 1.1 4.4e-17 62.0 1.1 1.3 1 0 0 1 1 1 1 Aminotransferase ubiquitination site Aminotran_5 PF00266.19 KFO95598.1 - 4.4e-06 25.9 0.0 6.5e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KFO95598.1 - 0.00058 19.3 0.0 0.00087 18.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KFO95598.1 - 0.0022 17.3 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KFO95598.1 - 0.0058 15.2 0.0 0.0087 14.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme MARVEL PF01284.23 KFO95599.1 - 2.6e-06 27.5 4.8 3.6e-06 27.1 4.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain Trp_oprn_chp PF09534.10 KFO95599.1 - 0.091 12.6 0.3 2.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF997 PF06196.12 KFO95599.1 - 1.3 9.1 12.1 0.7 9.9 8.0 2.7 2 1 2 4 4 4 0 Protein of unknown function (DUF997) Consortin_C PF15281.6 KFO95599.1 - 1.6 8.8 9.0 1.1 9.3 0.1 3.1 3 0 0 3 3 3 0 Consortin C-terminus Adaptin_N PF01602.20 KFO95601.1 - 3.2e-154 514.4 8.9 3.9e-154 514.1 8.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KFO95601.1 - 5.3e-35 120.1 5.1 1e-34 119.2 5.1 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KFO95601.1 - 7e-13 48.9 3.8 1.9e-09 37.7 0.1 3.5 2 2 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 AXH PF08517.12 KFO95602.1 - 3.6e-41 140.4 0.0 6.5e-41 139.5 0.0 1.4 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) zf-C2H2_4 PF13894.6 KFO95603.1 - 1.1e-06 29.0 7.0 0.0026 18.5 0.0 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KFO95603.1 - 3.9e-06 27.1 2.9 1.6 9.2 0.0 3.5 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 KFO95603.1 - 0.0019 18.0 1.8 2.2 8.2 0.1 3.4 2 1 0 2 2 2 2 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 KFO95603.1 - 0.0022 18.2 1.7 0.0022 18.2 1.7 2.3 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 KFO95603.1 - 0.0031 17.2 0.3 0.0031 17.2 0.3 3.0 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2 PF00096.26 KFO95603.1 - 0.0052 17.2 0.0 0.0052 17.2 0.0 3.6 4 0 0 4 4 3 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFO95603.1 - 0.009 16.0 1.0 4.6 7.3 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger DZR PF12773.7 KFO95603.1 - 0.012 15.6 3.4 0.077 13.0 2.4 2.6 2 1 1 3 3 3 0 Double zinc ribbon Rad50_zn_hook PF04423.14 KFO95603.1 - 0.025 14.4 1.7 1 9.2 0.0 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-H2C2_2 PF13465.6 KFO95603.1 - 0.056 13.9 2.1 5.3 7.6 0.0 3.5 4 0 0 4 4 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFO95603.1 - 0.09 13.1 0.0 61 4.1 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Prok-RING_4 PF14447.6 KFO95603.1 - 0.38 10.6 7.2 24 4.9 0.5 3.9 4 0 0 4 4 4 0 Prokaryotic RING finger family 4 zf-FPG_IleRS PF06827.14 KFO95603.1 - 2.4 8.1 0.0 2.4 8.1 0.0 3.2 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS PhnA_Zn_Ribbon PF08274.12 KFO95603.1 - 4.6 7.3 11.6 9.4 6.3 0.1 3.8 4 0 0 4 4 4 0 PhnA Zinc-Ribbon Ist1 PF03398.14 KFO95604.1 - 7.9e-63 211.3 4.0 9.6e-63 211.0 4.0 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DHO_dh PF01180.21 KFO95605.1 - 4.4e-107 357.7 0.0 5.2e-107 357.4 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 KFO95605.1 - 0.055 12.8 0.1 0.094 12.1 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase ACPS PF01648.20 KFO95605.1 - 0.19 11.8 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily OB_NTP_bind PF07717.16 KFO95606.1 - 3.1e-16 59.5 0.0 6.8e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KFO95606.1 - 6.6e-15 55.3 0.0 6.6e-15 55.3 0.0 4.7 4 1 0 4 4 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFO95606.1 - 9.7e-14 51.7 0.0 2.3e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFO95606.1 - 4.2e-07 29.9 0.0 1.1e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFO95606.1 - 2.4e-05 24.6 0.0 7.1e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFO95606.1 - 0.00065 19.5 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFO95606.1 - 0.0014 19.0 0.0 0.0034 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KFO95606.1 - 0.0026 17.1 1.0 0.011 15.0 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 KFO95606.1 - 0.0027 16.8 0.0 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 KFO95606.1 - 0.003 17.5 0.0 0.0069 16.4 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain PhoH PF02562.16 KFO95606.1 - 0.015 14.7 0.0 0.038 13.4 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.22 KFO95606.1 - 0.033 13.8 0.1 0.082 12.5 0.1 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KFO95606.1 - 0.07 13.5 0.0 0.23 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KFO95606.1 - 0.079 12.5 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KFO95606.1 - 0.19 11.9 0.0 0.19 11.9 0.0 3.1 3 0 0 3 3 1 0 AAA domain Homeodomain PF00046.29 KFO95607.1 - 1.4e-66 220.2 19.5 1.8e-17 62.9 0.7 5.0 4 0 0 4 4 4 4 Homeodomain zf-C2H2_4 PF13894.6 KFO95607.1 - 4.1e-14 52.1 134.3 0.1 13.5 3.7 22.5 23 0 0 23 23 23 12 C2H2-type zinc finger zf-C2H2 PF00096.26 KFO95607.1 - 2.6e-13 49.6 155.3 0.0048 17.3 0.4 22.3 24 0 0 24 24 24 12 Zinc finger, C2H2 type Homeobox_KN PF05920.11 KFO95607.1 - 8.1e-11 41.7 2.2 0.035 14.0 0.1 4.8 4 0 0 4 4 4 3 Homeobox KN domain zf-met PF12874.7 KFO95607.1 - 2.3e-07 31.0 96.7 0.00038 20.7 0.9 16.0 16 0 0 16 16 16 8 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFO95607.1 - 1.1e-05 25.6 5.8 1.1e-05 25.6 5.8 10.9 12 1 1 13 13 13 4 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 KFO95607.1 - 0.00051 19.7 0.8 0.00051 19.7 0.8 11.3 11 0 0 11 11 11 4 C2H2-type zinc-finger domain MerR_1 PF13411.6 KFO95607.1 - 0.019 15.1 0.2 0.27 11.4 0.0 3.1 4 0 0 4 4 4 0 MerR HTH family regulatory protein GLTT PF01744.20 KFO95607.1 - 0.07 12.9 1.0 0.15 11.8 1.0 1.6 1 0 0 1 1 1 0 GLTT repeat (6 copies) zf_Hakai PF18408.1 KFO95607.1 - 4.6 7.0 5.5 39 4.0 0.5 3.9 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain Lamprin PF06403.11 KFO95608.1 - 1.6e-05 24.9 16.5 0.0015 18.5 3.6 2.0 1 1 1 2 2 2 2 Lamprin Chorion_1 PF01723.16 KFO95608.1 - 0.027 14.5 24.3 71 3.3 24.3 2.2 1 1 0 1 1 1 0 Chorion protein MitMem_reg PF13012.6 KFO95609.1 - 3.2e-36 124.2 0.5 5.3e-36 123.4 0.5 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KFO95609.1 - 1.2e-25 89.8 1.8 1.7e-25 89.3 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Coilin_N PF15862.5 KFO95609.1 - 0.003 17.4 8.6 0.0051 16.6 8.6 1.3 1 0 0 1 1 1 1 Coilin N-terminus Connexin PF00029.19 KFO95609.1 - 0.027 14.2 5.6 0.048 13.4 5.6 1.3 1 0 0 1 1 1 0 Connexin HECT PF00632.25 KFO95610.1 - 6.5e-100 334.6 0.5 1e-99 333.9 0.5 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KFO95610.1 - 1.6e-48 162.4 33.8 1e-13 51.1 4.8 4.6 4 0 0 4 4 4 4 WW domain RHD_dimer PF16179.5 KFO95611.1 - 1.4e-27 95.7 0.1 1.4e-27 95.7 0.1 2.2 2 0 0 2 2 2 1 Rel homology dimerisation domain RHD_DNA_bind PF00554.22 KFO95611.1 - 5.1e-21 75.3 0.1 3.6e-20 72.6 0.1 2.5 1 1 0 1 1 1 1 Rel homology DNA-binding domain DUF4648 PF15505.6 KFO95611.1 - 3.4 8.6 7.3 6.1 7.8 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4648) TERF2_RBM PF16772.5 KFO95612.1 - 5.1e-18 64.2 0.1 1.1e-17 63.1 0.1 1.6 1 0 0 1 1 1 1 Telomeric repeat-binding factor 2 Rap1-binding motif TRF PF08558.10 KFO95612.1 - 2e-16 60.3 0.6 3.3e-16 59.6 0.6 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 KFO95612.1 - 1.7e-11 44.1 1.3 1.7e-11 44.1 1.3 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFO95612.1 - 0.00064 19.9 1.2 0.0025 18.0 1.2 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ribosomal_L36e PF01158.18 KFO95612.1 - 0.099 12.9 2.7 0.21 11.8 2.7 1.6 1 0 0 1 1 1 0 Ribosomal protein L36e EMP24_GP25L PF01105.24 KFO95613.1 - 5.1e-29 101.5 0.1 5.8e-29 101.3 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD UPF0113_N PF17833.1 KFO95614.1 - 8.4e-31 106.4 0.0 1.4e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KFO95614.1 - 3e-22 78.7 0.0 4.3e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain PUA PF01472.20 KFO95614.1 - 0.072 13.1 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 PUA domain PEPCK_GTP PF00821.18 KFO95614.1 - 0.14 11.0 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain Dor1 PF04124.12 KFO95615.1 - 8.9e-121 402.7 0.0 1.1e-120 402.4 0.0 1.1 1 0 0 1 1 1 1 Dor1-like family Vps51 PF08700.11 KFO95615.1 - 0.0023 18.0 0.0 0.0096 16.0 0.0 2.0 2 0 0 2 2 2 1 Vps51/Vps67 Vps4_C PF09336.10 KFO95617.1 - 1.6e-26 92.0 0.2 2.7e-26 91.3 0.2 1.4 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 KFO95617.1 - 1.6e-10 40.6 0.0 4.5e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 KFO95617.1 - 0.00017 22.0 0.0 0.00044 20.7 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 KFO95618.1 - 1.7e-30 106.1 0.0 2.9e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KFO95618.1 - 1.4e-06 27.7 0.0 2e-06 27.2 0.0 1.3 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KFO95618.1 - 1.8e-06 28.2 0.1 0.00043 20.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFO95618.1 - 2.2e-06 28.2 0.1 0.00093 19.6 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 KFO95618.1 - 2.6e-06 27.3 0.0 3.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 KFO95618.1 - 1.7e-05 24.9 0.0 2.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFO95618.1 - 2.5e-05 24.3 0.0 7.6e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFO95618.1 - 2.6e-05 24.0 0.0 3.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 KFO95618.1 - 3.5e-05 23.5 0.1 0.23 11.0 0.0 2.2 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.13 KFO95618.1 - 9.7e-05 21.6 0.0 0.00013 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KFO95618.1 - 0.00016 22.2 0.0 0.00032 21.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KFO95618.1 - 0.00031 20.9 0.0 0.00053 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KFO95618.1 - 0.00042 20.5 0.0 0.001 19.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 KFO95618.1 - 0.002 17.6 0.0 0.88 9.0 0.0 2.3 1 1 1 2 2 2 1 Bacterial TniB protein ATPase PF06745.13 KFO95618.1 - 0.0032 16.8 0.1 1.5 8.1 0.0 2.1 1 1 1 2 2 2 2 KaiC RNA_helicase PF00910.22 KFO95618.1 - 0.0035 17.7 0.0 0.0056 17.0 0.0 1.6 1 1 0 1 1 1 1 RNA helicase NACHT PF05729.12 KFO95618.1 - 0.0039 17.1 0.0 0.082 12.8 0.0 2.1 1 1 1 2 2 2 1 NACHT domain AAA_24 PF13479.6 KFO95618.1 - 0.0044 16.8 0.0 0.0072 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KFO95618.1 - 0.0063 16.0 0.0 0.014 14.9 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 KFO95618.1 - 0.0083 15.5 0.2 0.02 14.3 0.0 1.7 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KFO95618.1 - 0.0085 15.6 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_17 PF13207.6 KFO95618.1 - 0.0087 16.5 0.0 0.03 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KFO95618.1 - 0.012 15.3 0.0 0.05 13.3 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 KFO95618.1 - 0.013 15.4 0.0 1.6 8.6 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 KFO95618.1 - 0.018 15.2 0.0 0.046 13.9 0.0 1.7 2 1 0 2 2 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 KFO95618.1 - 0.034 13.9 0.0 0.062 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 KFO95618.1 - 0.036 13.2 0.0 0.063 12.4 0.0 1.4 2 0 0 2 2 1 0 MCM P-loop domain AFG1_ATPase PF03969.16 KFO95618.1 - 0.051 12.5 0.0 0.054 12.4 0.0 1.1 1 0 0 1 1 1 0 AFG1-like ATPase Zeta_toxin PF06414.12 KFO95618.1 - 0.07 12.4 0.1 0.58 9.4 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin Parvo_NS1 PF01057.17 KFO95618.1 - 0.072 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KFO95618.1 - 0.073 13.3 0.0 0.13 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain Guanylate_kin PF00625.21 KFO95618.1 - 0.077 12.7 0.0 0.32 10.6 0.0 1.9 1 1 0 2 2 2 0 Guanylate kinase KAP_NTPase PF07693.14 KFO95618.1 - 0.085 12.1 0.0 0.2 10.8 0.0 1.7 1 1 0 1 1 1 0 KAP family P-loop domain ResIII PF04851.15 KFO95618.1 - 0.086 12.8 0.0 0.13 12.2 0.0 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 KFO95618.1 - 0.13 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KFO95618.1 - 0.13 12.7 0.0 0.22 12.0 0.0 1.4 1 1 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 KFO95618.1 - 0.15 12.2 0.0 2.5 8.2 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 KFO95618.1 - 0.15 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.11 KFO95618.1 - 0.16 12.0 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Torsin PH_17 PF18012.1 KFO95619.1 - 1.7e-28 98.1 0.3 4.2e-28 96.9 0.3 1.6 1 0 0 1 1 1 1 PH domain PH PF00169.29 KFO95619.1 - 7.9e-10 39.2 0.0 6.1e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 PH domain PDZ PF00595.24 KFO95619.1 - 2.8e-06 27.6 0.1 5.1e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFO95619.1 - 0.0039 17.0 0.2 0.0086 15.9 0.2 1.6 1 0 0 1 1 1 1 PDZ domain ANAPC4_WD40 PF12894.7 KFO95620.1 - 1.3e-10 41.4 0.0 0.054 13.8 0.0 4.7 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFO95620.1 - 5.3e-06 27.1 12.4 0.33 11.9 0.1 6.7 7 0 0 7 7 7 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KFO95620.1 - 0.00049 19.1 0.0 0.0084 15.1 0.0 2.7 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 KFO95620.1 - 0.038 13.0 0.0 0.054 12.5 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Frtz PF11768.8 KFO95620.1 - 0.11 10.8 0.0 0.33 9.2 0.0 1.7 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Ctf8 PF09696.10 KFO95621.1 - 3.1e-07 30.8 0.5 3.8e-06 27.3 0.5 1.9 1 1 0 1 1 1 1 Ctf8 Chitin_synth_2 PF03142.15 KFO95622.1 - 7.1e-14 51.3 1.0 7.1e-10 38.1 0.5 3.3 2 1 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.6 KFO95622.1 - 1.2e-12 48.2 0.1 5.8e-08 32.9 0.1 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KFO95622.1 - 1.4e-06 28.4 11.1 3.6e-06 27.0 11.1 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KFO95622.1 - 0.00028 20.7 0.0 0.00061 19.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 NeA_P2 PF12312.8 KFO95622.1 - 0.0084 15.6 0.1 0.016 14.6 0.1 1.4 1 0 0 1 1 1 1 Nepovirus subgroup A polyprotein Glyco_transf_21 PF13506.6 KFO95622.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 DUF1294 PF06961.13 KFO95622.1 - 0.13 12.5 1.1 0.39 11.0 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1294) NIBRIN_BRCT_II PF16508.5 KFO95622.1 - 0.2 12.0 0.0 0.34 11.2 0.0 1.3 1 0 0 1 1 1 0 Second BRCT domain on Nijmegen syndrome breakage protein RTP1_C1 PF10363.9 KFO95623.1 - 5.8e-29 100.5 2.8 1.4e-28 99.3 0.2 3.1 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 KFO95623.1 - 5.2e-10 38.8 1.2 1.5e-09 37.3 1.2 1.9 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 HEAT_2 PF13646.6 KFO95623.1 - 1.9e-06 28.1 4.3 0.0059 17.0 0.6 3.3 2 0 0 2 2 2 2 HEAT repeats HEAT PF02985.22 KFO95623.1 - 4.8e-05 23.3 5.7 2.6 8.5 0.1 6.2 4 1 1 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 KFO95623.1 - 0.065 13.8 15.0 0.072 13.6 0.1 5.1 5 1 0 5 5 5 0 HEAT-like repeat Telomere_reg-2 PF10193.9 KFO95623.1 - 0.11 12.9 9.9 0.71 10.3 0.1 4.6 5 0 0 5 5 5 0 Telomere length regulation protein TPR_12 PF13424.6 KFO95623.1 - 0.19 12.0 1.1 24 5.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Transthyretin PF00576.21 KFO95624.1 - 2e-24 86.4 0.0 2.2e-24 86.3 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family GAS PF13851.6 KFO95625.1 - 1.7e-72 243.0 33.6 1.7e-72 243.0 33.6 3.1 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding Endonuc-dimeris PF09124.10 KFO95625.1 - 2.1 8.6 7.5 3.6 7.8 1.6 3.2 2 0 0 2 2 2 0 T4 recombination endonuclease VII, dimerisation Dysbindin PF04440.16 KFO95626.1 - 9.8e-34 116.6 0.0 1.2e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Dysbindin (Dystrobrevin binding protein 1) zf-RING_9 PF13901.6 KFO95627.1 - 2.4e-65 220.4 24.8 5.2e-65 219.3 11.1 2.2 2 0 0 2 2 2 2 Putative zinc-RING and/or ribbon C1_1 PF00130.22 KFO95627.1 - 2.5e-07 30.4 7.7 2.5e-07 30.4 7.7 4.6 3 2 2 5 5 5 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Tubulin PF00091.25 KFO95628.1 - 9.9e-60 202.1 0.0 1.5e-59 201.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFO95628.1 - 8.1e-43 145.6 0.1 1.3e-42 144.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFO95628.1 - 0.014 15.1 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 KFO95628.1 - 0.042 13.0 0.0 0.078 12.1 0.0 1.4 1 0 0 1 1 1 0 Tubulin like Tcf25 PF04910.14 KFO95631.1 - 4.4e-123 410.8 5.1 6.1e-123 410.3 5.1 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_12 PF13424.6 KFO95631.1 - 0.061 13.6 2.7 0.18 12.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat KIND PF16474.5 KFO95632.1 - 7.1e-45 153.3 0.0 1.3e-44 152.4 0.0 1.4 1 0 0 1 1 1 1 Kinase non-catalytic C-lobe domain PrmA PF06325.13 KFO95632.1 - 0.012 15.0 0.1 0.018 14.5 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FYVE_2 PF02318.16 KFO95632.1 - 0.13 12.4 6.0 0.37 11.0 6.0 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger Fanconi_A_N PF15865.5 KFO95633.1 - 4.4e-120 401.2 4.7 4.4e-120 401.2 4.7 2.0 2 0 0 2 2 2 1 Fanconi anaemia group A protein N terminus Fanconi_A PF03511.14 KFO95633.1 - 2.6e-25 88.1 3.4 1e-24 86.2 0.6 3.1 2 0 0 2 2 2 1 Fanconi anaemia group A protein zf-C2H2 PF00096.26 KFO95634.1 - 3.6e-14 52.3 41.3 0.00012 22.3 2.2 6.5 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO95634.1 - 2.1e-13 49.9 40.3 0.0032 18.2 0.8 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFO95634.1 - 3.4e-07 30.4 48.1 0.0003 21.1 1.1 7.2 7 1 0 7 7 7 4 Zinc-finger double domain CpXC PF14353.6 KFO95634.1 - 0.0077 16.3 15.6 0.23 11.5 0.2 4.1 2 1 2 4 4 4 2 CpXC protein Zn-ribbon_8 PF09723.10 KFO95634.1 - 0.0089 16.1 20.4 0.15 12.2 0.0 4.3 4 0 0 4 4 4 2 Zinc ribbon domain zf-C2H2_6 PF13912.6 KFO95634.1 - 0.0095 15.9 0.3 0.0095 15.9 0.3 5.5 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KFO95634.1 - 0.011 15.9 3.0 0.011 15.9 3.0 2.3 1 1 1 2 2 2 0 Aberrant zinc-finger zf_UBZ PF18439.1 KFO95634.1 - 0.25 11.0 16.2 0.86 9.3 0.1 4.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger RbpA PF13397.6 KFO95634.1 - 1.3 9.7 4.5 15 6.3 0.2 3.1 3 1 0 3 3 3 0 RNA polymerase-binding protein ADK_lid PF05191.14 KFO95634.1 - 3 7.9 15.5 0.063 13.3 1.4 3.8 4 0 0 4 4 4 0 Adenylate kinase, active site lid RBR PF17208.3 KFO95634.1 - 3.4 8.5 17.5 0.47 11.2 12.5 2.2 2 0 0 2 2 1 0 RNA binding Region zf-AD PF07776.15 KFO95634.1 - 4.9 7.5 12.6 1.4 9.2 1.1 3.6 3 0 0 3 3 3 0 Zinc-finger associated domain (zf-AD) Pkinase PF00069.25 KFO95635.1 - 2.8e-66 223.6 0.0 3.2e-66 223.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO95635.1 - 4.8e-35 121.1 0.0 6.8e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFO95635.1 - 3.2e-10 39.8 0.1 3.6e-06 26.5 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 KFO95635.1 - 1.2e-06 27.7 0.1 3.3e-06 26.3 0.1 1.6 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KFO95635.1 - 0.0022 17.6 0.1 0.0034 17.0 0.1 1.3 1 1 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KFO95635.1 - 0.0071 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFO95635.1 - 0.019 14.9 0.0 0.042 13.8 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KFO95635.1 - 0.034 13.5 0.1 0.071 12.5 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Herpes_IE1 PF07340.11 KFO95635.1 - 0.15 11.0 0.1 0.21 10.5 0.1 1.1 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein Snf7 PF03357.21 KFO95636.1 - 1.3e-10 41.1 16.0 1.7e-10 40.8 16.0 1.1 1 0 0 1 1 1 1 Snf7 DMSP_lyase PF16867.5 KFO95636.1 - 0.08 12.6 0.5 0.13 11.9 0.5 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Fes1 PF08609.10 KFO95636.1 - 6.2 7.8 8.6 3.6 8.5 4.2 2.6 1 1 1 2 2 2 0 Nucleotide exchange factor Fes1 Peptidase_M19 PF01244.21 KFO95637.1 - 5.2e-47 160.6 1.0 5.6e-47 160.5 1.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) RTX_C PF08339.10 KFO95637.1 - 0.056 13.5 0.0 0.066 13.3 0.0 1.2 1 0 0 1 1 1 0 RTX C-terminal domain Copine PF07002.16 KFO95638.1 - 5.7e-93 310.3 0.0 8e-93 309.9 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 KFO95638.1 - 2.3e-30 104.9 0.1 1.3e-14 54.4 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 KFO95638.1 - 0.0002 21.6 0.0 0.00042 20.5 0.0 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 KFO95638.1 - 0.00051 20.3 0.0 0.00086 19.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Ribosomal_L13e PF01294.18 KFO95639.1 - 2.4e-80 268.6 6.2 3.1e-80 268.2 6.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Peptidase_M41 PF01434.18 KFO95640.1 - 3.6e-63 212.9 0.0 6.8e-63 212.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KFO95640.1 - 5.8e-39 133.5 0.0 1.6e-38 132.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFO95640.1 - 1e-14 54.0 0.0 3.7e-14 52.2 0.0 2.0 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 KFO95640.1 - 1.5e-06 28.2 0.3 2.5e-05 24.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 KFO95640.1 - 3e-06 27.7 0.0 7.3e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain FtsH_ext PF06480.15 KFO95640.1 - 3.1e-06 27.5 0.0 8.9e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.6 KFO95640.1 - 0.0002 21.6 0.1 0.032 14.5 0.0 3.4 1 1 2 3 3 3 1 AAA domain AAA_2 PF07724.14 KFO95640.1 - 0.00083 19.5 1.3 0.0018 18.4 0.0 2.2 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KFO95640.1 - 0.00094 19.0 0.2 0.005 16.6 0.0 2.1 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFO95640.1 - 0.0016 18.9 0.2 0.0052 17.2 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KFO95640.1 - 0.0043 16.3 0.1 0.0079 15.4 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 KFO95640.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KFO95640.1 - 0.03 14.0 0.1 0.083 12.6 0.1 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein PglZ PF08665.12 KFO95640.1 - 0.081 13.0 0.0 1 9.4 0.0 2.6 2 0 0 2 2 2 0 PglZ domain NACHT PF05729.12 KFO95640.1 - 0.1 12.5 0.0 0.31 11.0 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 KFO95640.1 - 0.12 12.6 0.5 0.26 11.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain Peptidase_M50B PF13398.6 KFO95640.1 - 0.12 12.0 0.8 0.34 10.5 0.1 2.0 2 0 0 2 2 2 0 Peptidase M50B-like TMEM208_SND2 PF05620.11 KFO95640.1 - 0.27 11.0 1.2 0.58 9.9 0.3 2.0 1 1 1 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Ank_2 PF12796.7 KFO95641.1 - 2.1e-18 66.7 0.2 2.9e-09 37.4 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFO95641.1 - 8.4e-18 64.0 0.4 0.00017 21.8 0.1 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KFO95641.1 - 1.8e-17 63.2 0.3 3.6e-08 33.5 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFO95641.1 - 3.2e-14 53.1 0.2 3.7e-06 27.4 0.0 3.2 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFO95641.1 - 8.4e-14 50.3 0.1 0.0007 19.9 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat YcbB PF08664.10 KFO95642.1 - 0.021 14.9 1.8 0.021 14.9 1.8 2.4 2 0 0 2 2 2 0 YcbB domain DUF3348 PF11828.8 KFO95642.1 - 0.079 12.6 6.8 0.18 11.5 6.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) AMP-binding PF00501.28 KFO95643.1 - 7.5e-81 271.9 0.0 9.8e-81 271.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFO95643.1 - 5.9e-15 56.0 0.1 1.3e-14 54.9 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ATR13 PF16829.5 KFO95643.1 - 0.089 13.2 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Avirulence protein ATR13, RxLR effector TAFH PF07531.14 KFO95645.1 - 4.5e-35 119.6 1.1 8.6e-35 118.7 1.1 1.5 1 0 0 1 1 1 1 NHR1 homology to TAF NHR2 PF08788.11 KFO95645.1 - 1.1e-27 95.6 1.6 3.3e-27 94.0 1.6 1.9 1 0 0 1 1 1 1 NHR2 domain like zf-MYND PF01753.18 KFO95645.1 - 1.3e-07 31.6 16.9 1.3e-07 31.6 16.9 2.1 2 0 0 2 2 2 1 MYND finger Efg1 PF10153.9 KFO95645.1 - 0.0076 16.6 1.2 0.022 15.1 1.2 1.7 1 0 0 1 1 1 1 rRNA-processing protein Efg1 vATP-synt_E PF01991.18 KFO95645.1 - 2.9 7.2 9.9 4.5 6.6 9.9 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit RRM_1 PF00076.22 KFO95646.1 - 3.2e-17 62.1 0.0 4.9e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 KFO95646.1 - 0.091 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 RL domain Sedlin_N PF04628.13 KFO95647.1 - 2.4e-33 115.1 0.7 2.7e-33 114.9 0.7 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KFO95647.1 - 5.7e-10 39.3 0.2 6.9e-10 39.0 0.2 1.1 1 0 0 1 1 1 1 Sybindin-like family Sulfatase PF00884.23 KFO95648.1 - 2.3e-79 267.0 0.0 3e-79 266.6 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KFO95648.1 - 4.2e-32 111.5 0.0 8e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 KFO95648.1 - 8.9e-09 35.4 0.1 3.9e-08 33.3 0.1 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase TFIIIC_delta PF12657.7 KFO95648.1 - 0.081 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term DUF229 PF02995.17 KFO95648.1 - 0.16 10.5 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Pribosyltran PF00156.27 KFO95649.1 - 4.5e-24 84.8 0.0 5.5e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KFO95649.1 - 0.00029 20.3 0.0 0.00041 19.8 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KFO95649.1 - 0.03 13.8 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase CDT1 PF08839.11 KFO95650.1 - 4.4e-60 203.0 0.5 2.7e-59 200.4 0.2 2.2 2 1 0 2 2 2 1 DNA replication factor CDT1 like CDT1_C PF16679.5 KFO95650.1 - 7.8e-36 122.4 0.9 2.3e-35 120.9 0.3 2.1 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain Mac PF12464.8 KFO95650.1 - 0.12 12.6 0.0 1.3 9.3 0.0 2.7 3 0 0 3 3 3 0 Maltose acetyltransferase zf-Di19 PF05605.12 KFO95651.1 - 3.4e-17 62.5 3.7 3.4e-17 62.5 3.7 3.0 2 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf_C2HC_14 PF18574.1 KFO95651.1 - 1.1e-13 50.7 3.4 3.7e-13 49.0 3.4 2.0 1 0 0 1 1 1 1 C2HC Zing finger domain UIM PF02809.20 KFO95651.1 - 0.00085 19.1 3.7 0.0014 18.4 3.7 1.4 1 0 0 1 1 1 1 Ubiquitin interaction motif Rubredoxin PF00301.20 KFO95651.1 - 0.0052 16.8 2.9 4.9 7.3 0.0 3.5 3 0 0 3 3 3 1 Rubredoxin zinc_ribbon_2 PF13240.6 KFO95651.1 - 0.024 14.3 0.2 0.024 14.3 0.2 4.4 4 0 0 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KFO95651.1 - 0.069 12.6 0.0 0.069 12.6 0.0 4.5 6 0 0 6 6 6 0 zinc-ribbon domain zf-C2H2_9 PF16293.5 KFO95651.1 - 0.11 12.3 9.5 1.3 9.0 0.3 3.3 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2_4 PF13894.6 KFO95651.1 - 0.29 12.1 0.6 0.29 12.1 0.6 5.3 5 1 0 5 5 4 0 C2H2-type zinc finger zinc_ribbon_10 PF10058.9 KFO95651.1 - 1.1 9.0 0.1 1.1 9.0 0.1 3.0 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-RING_2 PF13639.6 KFO95651.1 - 6.6 7.2 24.8 3.7 7.9 5.9 4.2 4 0 0 4 4 4 0 Ring finger domain Actin_micro PF17003.5 KFO95651.1 - 7.7 5.6 6.0 4.2 6.5 0.9 2.5 2 1 0 2 2 2 0 Putative actin-like family MDD_C PF18376.1 KFO95652.1 - 7.6e-63 211.6 0.0 1e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KFO95652.1 - 1.1e-06 28.7 2.4 1.1e-06 28.7 2.4 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain zf-CCCH_4 PF18044.1 KFO95653.1 - 1.3e-08 34.4 5.2 2.1e-08 33.8 5.2 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFO95653.1 - 1.9e-05 24.6 7.0 3.1e-05 23.9 7.0 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KFO95653.1 - 0.00036 20.4 3.2 0.00063 19.6 3.2 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KFO95653.1 - 0.0049 17.5 0.0 0.0049 17.5 0.0 2.7 2 0 0 2 2 2 1 Torus domain zf-CCCH_2 PF14608.6 KFO95653.1 - 0.38 11.3 6.4 0.87 10.1 6.4 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger CIDE-N PF02017.15 KFO95654.1 - 1.4e-13 50.6 0.1 2.2e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 CIDE-N domain BEN PF10523.9 KFO95655.1 - 3.9e-08 33.4 0.0 8.2e-07 29.2 0.0 2.5 2 0 0 2 2 2 1 BEN domain Secretin_N_2 PF07655.13 KFO95655.1 - 8.2 7.1 13.0 11 6.6 2.8 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain Carb_anhydrase PF00194.21 KFO95656.1 - 9.3e-87 290.8 0.0 1.1e-86 290.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Tudor_3 PF18115.1 KFO95656.1 - 0.043 13.7 0.0 1 9.3 0.0 2.7 3 0 0 3 3 3 0 DNA repair protein Crb2 Tudor domain AA_permease_2 PF13520.6 KFO95657.1 - 4.7e-63 213.5 42.5 5.5e-63 213.3 42.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFO95657.1 - 8.1e-25 87.3 38.6 1.2e-24 86.8 38.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4448 PF14610.6 KFO95657.1 - 0.15 11.8 2.2 3.1 7.5 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) SirB PF04247.12 KFO95657.1 - 0.23 11.6 9.1 0.13 12.4 0.5 2.8 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB MORN PF02493.20 KFO95658.1 - 1.3e-41 138.0 67.9 9.3e-10 37.8 0.9 8.5 8 0 0 8 8 8 8 MORN repeat zf-CCHC PF00098.23 KFO95659.1 - 7.4e-06 25.8 2.2 7.4e-06 25.8 2.2 2.4 3 0 0 3 3 3 1 Zinc knuckle SAM_1 PF00536.30 KFO95659.1 - 0.00029 21.2 0.6 0.00059 20.2 0.6 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFO95659.1 - 0.025 14.7 0.3 0.049 13.8 0.3 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Atg8 PF02991.16 KFO95660.1 - 1.6e-43 147.1 0.2 1.8e-43 147.0 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KFO95660.1 - 1.5e-06 28.5 0.0 1.8e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Rad60-SLD PF11976.8 KFO95660.1 - 0.066 13.0 0.1 0.54 10.1 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Cytochrom_B559a PF00284.20 KFO95660.1 - 0.14 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit DUF3506 PF12014.8 KFO95661.1 - 0.00073 19.6 2.2 0.12 12.4 0.1 3.3 2 1 2 4 4 4 2 Domain of unknown function (DUF3506) SBF2 PF12335.8 KFO95662.1 - 9.9e-05 22.1 2.2 0.00015 21.5 0.2 2.1 2 0 0 2 2 2 1 Myotubularin protein Sld5 PF05916.11 KFO95663.1 - 1.7e-13 51.0 0.7 1.9e-13 50.9 0.7 1.0 1 0 0 1 1 1 1 GINS complex protein CREPT PF16566.5 KFO95663.1 - 0.043 14.0 0.0 0.051 13.8 0.0 1.1 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour UPF0172 PF03665.13 KFO95664.1 - 6.9e-65 218.7 0.0 7.8e-65 218.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) BBS2_Mid PF14783.6 KFO95664.1 - 0.067 13.2 0.0 0.092 12.8 0.0 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region COX4 PF02936.14 KFO95665.1 - 6.3e-58 194.7 0.4 7.2e-58 194.5 0.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV IRF-3 PF10401.9 KFO95666.1 - 1.7e-66 223.4 0.2 2.5e-66 222.9 0.2 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.17 KFO95666.1 - 3.5e-42 143.0 0.6 6.3e-42 142.1 0.6 1.4 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor MH2 PF03166.14 KFO95666.1 - 0.00079 19.7 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 MH2 domain tRNA-synt_1 PF00133.22 KFO95667.1 - 4.4e-165 550.4 0.3 6.4e-165 549.8 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KFO95667.1 - 5.2e-27 94.7 0.2 1.7e-26 93.0 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KFO95667.1 - 1.9e-25 89.4 0.8 2e-16 59.8 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KFO95667.1 - 5.9e-05 22.6 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KFO95667.1 - 0.00041 19.8 0.0 0.17 11.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.14 KFO95667.1 - 8.8 6.3 10.3 1.2e+02 2.7 10.3 2.6 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS RAB3GAP2_C PF14656.6 KFO95668.1 - 1.1e-229 763.8 19.2 1.7e-229 763.1 19.2 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit C-terminus RAB3GAP2_N PF14655.6 KFO95668.1 - 1.9e-165 551.2 0.0 3e-165 550.5 0.0 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus SRP54_N PF02881.19 KFO95668.1 - 2.6 8.3 0.0 2.6 8.3 0.0 4.0 4 1 0 5 5 5 0 SRP54-type protein, helical bundle domain Pkinase PF00069.25 KFO95669.1 - 7e-76 255.1 0.0 1e-75 254.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO95669.1 - 5.6e-44 150.4 0.0 8.3e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KFO95669.1 - 9.5e-21 73.3 0.0 1.7e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 KFO95669.1 - 4.3e-07 29.6 0.0 9.8e-07 28.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like UBA PF00627.31 KFO95669.1 - 8.6e-07 28.7 0.0 1.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RIO1 PF01163.22 KFO95669.1 - 0.00055 19.6 0.2 0.0011 18.6 0.2 1.4 1 0 0 1 1 1 1 RIO1 family UBA_2 PF08587.11 KFO95669.1 - 0.0035 17.4 0.1 0.0089 16.1 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kdo PF06293.14 KFO95669.1 - 0.0074 15.7 0.1 0.015 14.7 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFO95669.1 - 0.071 12.0 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KFO95669.1 - 0.074 13.0 0.1 0.26 11.2 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family JmjC PF02373.22 KFO95670.1 - 2.3e-16 60.2 0.1 1e-15 58.2 0.1 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase 7tm_4 PF13853.6 KFO95671.1 - 2.6e-34 119.2 5.0 2.8e-34 119.1 5.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO95671.1 - 3.6e-14 52.7 10.7 7.1e-14 51.8 10.7 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Rax2 PF12768.7 KFO95671.1 - 0.06 12.8 0.1 0.085 12.3 0.1 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Granin PF01271.17 KFO95672.1 - 6.6e-117 391.8 32.5 7.5e-117 391.7 32.5 1.0 1 0 0 1 1 1 1 Granin (chromogranin or secretogranin) IF2_N PF04760.15 KFO95672.1 - 0.018 14.8 0.7 1.9 8.4 0.1 3.1 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region DivIVA PF05103.13 KFO95672.1 - 6.2 6.9 10.7 0.58 10.3 1.0 3.3 4 0 0 4 4 4 0 DivIVA protein Clat_adaptor_s PF01217.20 KFO95673.1 - 9.7e-59 197.4 3.3 1.1e-58 197.2 3.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CNOT1_HEAT PF16418.5 KFO95673.1 - 0.069 13.2 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 HEAT repeat zf-H2C2_2 PF13465.6 KFO95674.1 - 5.3e-49 162.6 51.9 7.7e-12 45.1 0.7 6.4 7 0 0 7 7 6 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFO95674.1 - 1.5e-35 119.7 48.6 7.4e-07 29.3 0.3 6.1 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO95674.1 - 9.2e-26 88.3 45.6 9.7e-06 26.0 1.5 6.1 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO95674.1 - 1.3e-16 60.3 15.5 0.00088 19.5 0.0 6.1 6 0 0 6 6 6 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFO95674.1 - 1.4e-08 34.5 43.1 0.0047 16.9 0.2 6.8 7 0 0 7 7 7 4 C2H2-type zinc finger CpXC PF14353.6 KFO95674.1 - 1.2e-07 31.7 19.0 0.31 11.1 2.4 5.8 4 2 0 4 4 4 3 CpXC protein zf_UBZ PF18439.1 KFO95674.1 - 4.4e-07 29.4 19.3 0.94 9.1 0.1 6.2 6 0 0 6 6 6 2 Ubiquitin-Binding Zinc Finger Zn_ribbon_SprT PF17283.2 KFO95674.1 - 1.7e-06 27.8 27.9 0.024 14.6 4.4 5.0 4 1 1 5 5 5 3 SprT-like zinc ribbon domain zf-LYAR PF08790.11 KFO95674.1 - 1.7e-06 27.8 13.7 0.72 9.8 0.1 6.2 6 0 0 6 6 6 1 LYAR-type C2HC zinc finger Zn-ribbon_8 PF09723.10 KFO95674.1 - 3e-06 27.2 26.4 0.005 16.9 2.3 4.3 2 1 2 4 4 4 2 Zinc ribbon domain zf-Di19 PF05605.12 KFO95674.1 - 4.1e-06 27.0 28.9 0.013 15.8 3.8 4.8 2 2 1 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.7 KFO95674.1 - 9.1e-06 25.6 20.9 0.046 13.7 1.1 3.4 2 1 0 2 2 2 2 Double zinc ribbon zinc_ribbon_5 PF13719.6 KFO95674.1 - 1.7e-05 24.4 19.9 0.11 12.3 0.0 6.0 6 0 0 6 6 6 1 zinc-ribbon domain TRAF6_Z2 PF18048.1 KFO95674.1 - 3e-05 24.0 29.7 0.75 9.9 0.4 6.4 6 0 0 6 6 6 2 TNF receptor-associated factor 6 zinc finger 2 DUF3268 PF11672.8 KFO95674.1 - 8.1e-05 22.9 9.5 0.12 12.7 0.4 3.2 2 1 0 3 3 3 2 zinc-finger-containing domain FYDLN_acid PF09538.10 KFO95674.1 - 9e-05 23.1 16.9 7.4 7.3 0.0 5.8 1 1 3 5 5 5 0 Protein of unknown function (FYDLN_acid) YacG PF03884.14 KFO95674.1 - 0.0001 21.9 14.3 1 9.2 0.0 5.8 6 0 0 6 6 6 1 DNA gyrase inhibitor YacG zinc_ribbon_15 PF17032.5 KFO95674.1 - 0.0002 22.1 10.7 1.5 9.6 0.5 3.3 1 1 2 3 3 3 3 zinc-ribbon family zinc_ribbon_9 PF14369.6 KFO95674.1 - 0.0008 19.6 22.7 2.6 8.4 0.2 6.0 6 0 0 6 6 6 2 zinc-ribbon zf-C2H2_2 PF12756.7 KFO95674.1 - 0.00088 19.6 21.2 0.56 10.6 0.1 5.5 1 1 5 6 6 6 2 C2H2 type zinc-finger (2 copies) HypA PF01155.19 KFO95674.1 - 0.0011 18.9 12.8 1.7 8.7 2.6 3.4 1 1 1 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA GAGA PF09237.11 KFO95674.1 - 0.0093 15.8 25.4 0.8 9.6 2.4 5.0 2 2 3 5 5 5 2 GAGA factor XPA_N PF01286.18 KFO95674.1 - 0.013 15.6 17.9 6.7 6.9 0.3 5.9 6 0 0 6 6 6 0 XPA protein N-terminal OSTMP1 PF09777.9 KFO95674.1 - 0.018 14.5 0.3 0.034 13.6 0.1 1.5 1 1 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor C1_4 PF07975.12 KFO95674.1 - 0.027 14.7 16.4 0.62 10.3 0.8 4.2 2 1 2 4 4 4 0 TFIIH C1-like domain zf-AN1 PF01428.16 KFO95674.1 - 0.036 14.2 23.9 5.6 7.2 0.1 6.1 6 0 0 6 6 6 0 AN1-like Zinc finger zinc-ribbons_6 PF07191.12 KFO95674.1 - 0.05 13.6 19.3 7.2 6.7 1.9 4.1 1 1 2 3 3 3 0 zinc-ribbons zinc_ribbon_4 PF13717.6 KFO95674.1 - 0.087 12.8 28.3 4.4 7.3 0.1 6.1 6 0 0 6 6 6 0 zinc-ribbon domain zf-ZPR1 PF03367.13 KFO95674.1 - 0.12 12.3 0.2 0.12 12.3 0.2 2.9 3 1 1 4 4 3 0 ZPR1 zinc-finger domain DUF2256 PF10013.9 KFO95674.1 - 0.17 12.0 19.6 3.5 7.8 0.0 5.9 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn-C2H2_12 PF18112.1 KFO95674.1 - 0.18 12.3 19.6 12 6.4 0.4 6.2 6 0 0 6 6 6 0 Autophagy receptor zinc finger-C2H2 domain zf-DNA_Pol PF08996.10 KFO95674.1 - 0.21 11.3 12.8 3.5 7.3 3.0 3.3 1 1 2 3 3 3 0 DNA Polymerase alpha zinc finger zf-nanos PF05741.13 KFO95674.1 - 0.22 11.8 0.3 0.22 11.8 0.3 5.6 4 2 1 5 5 5 0 Nanos RNA binding domain TerY_C PF15616.6 KFO95674.1 - 0.29 11.2 0.1 0.29 11.2 0.1 3.1 1 1 2 3 3 3 0 TerY-C metal binding domain BolA PF01722.18 KFO95674.1 - 0.7 10.2 5.7 9.9 6.5 0.1 3.1 3 1 0 3 3 3 0 BolA-like protein zf-trcl PF13451.6 KFO95674.1 - 2.1 8.3 24.1 3.7 7.5 2.7 5.0 4 1 0 4 4 4 0 Probable zinc-ribbon domain CxC7 PF18866.1 KFO95674.1 - 2.8 8.2 19.0 5.9 7.1 0.5 5.3 2 2 4 6 6 6 0 CxC7 like cysteine cluster associated with KDZ transposases zf-C2H2_9 PF16293.5 KFO95674.1 - 3 7.8 11.1 27 4.7 0.1 5.2 6 0 0 6 6 6 0 C2H2 type zinc-finger (1 copy) zf-met PF12874.7 KFO95674.1 - 4.1 7.9 27.1 7.3 7.1 0.1 6.0 6 0 0 6 6 6 0 Zinc-finger of C2H2 type FdhE PF04216.12 KFO95674.1 - 4.2 7.2 13.4 2.4 8.0 0.5 3.2 1 1 0 2 2 2 0 Protein involved in formate dehydrogenase formation ATPase-cat_bd PF12156.8 KFO95674.1 - 8.1 7.3 15.7 0.41 11.4 1.1 3.1 2 1 0 3 3 3 0 Putative metal-binding domain of cation transport ATPase DUF4379 PF14311.6 KFO95674.1 - 8.3 6.9 25.5 3.5 8.1 1.4 4.2 2 1 3 5 5 5 0 Probable Zinc-ribbon domain LRR_8 PF13855.6 KFO95676.1 - 4.6e-33 112.8 33.2 2.7e-13 49.4 7.5 5.5 3 2 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 KFO95676.1 - 3.2e-18 65.5 31.9 0.00012 22.3 3.1 7.4 4 2 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFO95676.1 - 4.7e-10 39.5 0.1 0.084 12.8 0.0 3.5 2 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFO95676.1 - 5.8e-07 29.2 9.8 0.0034 16.9 0.2 3.3 2 1 1 3 3 3 3 Leucine-rich repeat LRRNT PF01462.18 KFO95676.1 - 7.8e-05 22.2 2.6 7.8e-05 22.2 2.6 3.8 5 0 0 5 5 5 1 Leucine rich repeat N-terminal domain LRRCT PF01463.24 KFO95676.1 - 0.00023 21.5 0.1 0.00069 20.0 0.1 1.9 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain fn3 PF00041.21 KFO95676.1 - 0.00029 21.1 0.0 0.00073 19.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain LRR_1 PF00560.33 KFO95676.1 - 0.0036 17.6 21.9 2.2 9.1 0.3 9.3 10 1 0 10 10 10 1 Leucine Rich Repeat Syndecan PF01034.20 KFO95676.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain LRR_6 PF13516.6 KFO95676.1 - 0.16 12.1 28.5 1.4 9.2 0.2 7.3 8 0 0 8 8 8 0 Leucine Rich repeat Glyco_hydro_59 PF02057.15 KFO95677.1 - 2.5e-110 368.3 1.3 3.2e-110 368.0 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_59M PF17387.2 KFO95677.1 - 5.8e-52 174.7 0.0 1.1e-51 173.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 central domain Laminin_G_3 PF13385.6 KFO95677.1 - 0.045 13.9 0.9 0.14 12.3 0.9 1.8 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Glyco_hydro_30 PF02055.16 KFO95677.1 - 0.05 12.6 0.1 0.097 11.6 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 TIM-barrel domain CRCB PF02537.15 KFO95677.1 - 0.1 12.9 0.2 3.2 8.1 0.0 2.4 2 0 0 2 2 2 0 CrcB-like protein, Camphor Resistance (CrcB) 7tm_1 PF00001.21 KFO95678.1 - 3.6e-42 144.5 22.2 5.3e-42 144.0 22.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFO95678.1 - 0.028 14.2 14.6 0.041 13.6 14.6 1.2 1 0 0 1 1 1 0 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFO95678.1 - 0.13 11.9 22.7 0.0091 15.6 13.6 2.2 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Ion_trans_2 PF07885.16 KFO95679.1 - 2.5e-35 120.3 27.3 8.4e-19 67.3 11.4 3.3 3 1 1 4 4 4 2 Ion channel DUF2390 PF09523.10 KFO95679.1 - 0.014 15.7 0.5 0.029 14.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) DmsC PF04976.12 KFO95679.1 - 0.071 12.6 0.2 0.071 12.6 0.2 2.9 1 1 0 2 2 2 0 DMSO reductase anchor subunit (DmsC) PDZ_3 PF17815.1 KFO95679.1 - 0.091 12.6 0.2 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 PDZ domain PLC-beta_C PF08703.10 KFO95679.1 - 0.094 12.7 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 PLC-beta C terminal TssN PF17555.2 KFO95679.1 - 0.1 12.0 4.2 0.29 10.5 2.0 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssN Docking PF08990.11 KFO95679.1 - 0.18 11.5 0.3 0.33 10.6 0.3 1.4 1 0 0 1 1 1 0 Erythronolide synthase docking E1-E2_ATPase PF00122.20 KFO95679.1 - 1.8 8.1 8.3 0.22 11.0 1.0 2.5 3 0 0 3 3 3 0 E1-E2 ATPase HSD3 PF15244.6 KFO95680.1 - 8.8e-34 117.7 1.7 1.3e-33 117.1 1.7 1.3 1 0 0 1 1 1 1 Spermatogenesis-associated protein 7, or HSD3 Y_phosphatase PF00102.27 KFO95681.1 - 1.3e-73 247.5 0.0 2.1e-73 246.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FERM_M PF00373.18 KFO95681.1 - 1.7e-21 76.8 2.7 5e-21 75.3 2.7 1.9 1 0 0 1 1 1 1 FERM central domain FERM_C PF09380.10 KFO95681.1 - 2.4e-18 66.3 0.3 5.9e-18 65.1 0.3 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KFO95681.1 - 4.7e-16 58.5 2.5 1e-15 57.4 0.2 2.7 3 0 0 3 3 3 1 FERM N-terminal domain DSPc PF00782.20 KFO95681.1 - 5.3e-06 26.3 0.0 1.3e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFO95681.1 - 0.00082 19.4 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFO95681.1 - 0.055 13.6 0.1 0.54 10.4 0.0 2.6 2 0 0 2 2 2 0 Inositol hexakisphosphate zf-CCCH_2 PF14608.6 KFO95682.1 - 6.9e-18 64.4 57.5 0.00013 22.3 7.4 5.4 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger PWI PF01480.17 KFO95682.1 - 0.053 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 PWI domain WD40 PF00400.32 KFO95683.1 - 9.8e-62 203.4 85.0 1.2e-05 25.9 0.1 26.8 30 0 0 30 30 30 15 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO95683.1 - 7.4e-39 132.0 5.2 1.3e-07 31.8 0.0 13.4 9 3 5 14 14 14 8 Anaphase-promoting complex subunit 4 WD40 domain HELP PF03451.14 KFO95683.1 - 3.9e-38 129.2 0.2 7.1e-20 70.6 0.0 2.4 2 0 0 2 2 2 2 HELP motif Ge1_WD40 PF16529.5 KFO95683.1 - 1.3e-06 27.7 3.6 0.34 9.8 0.0 6.7 4 3 3 7 7 7 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KFO95683.1 - 4e-05 22.6 0.0 0.11 11.2 0.0 3.9 4 0 0 4 4 4 2 Nup133 N terminal like Cytochrom_D1 PF02239.16 KFO95683.1 - 4.5e-05 22.2 11.3 0.16 10.5 0.0 6.7 7 1 1 8 8 8 3 Cytochrome D1 heme domain Nup160 PF11715.8 KFO95683.1 - 0.031 12.9 0.0 6.8 5.2 0.0 3.3 3 0 0 3 3 3 0 Nucleoporin Nup120/160 PD40 PF07676.12 KFO95683.1 - 0.14 12.2 1.3 2.1e+02 2.0 0.0 4.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat TPR_2 PF07719.17 KFO95684.1 - 4.9e-27 91.8 9.7 0.0041 17.1 0.0 8.6 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_1 PF00515.28 KFO95684.1 - 4.6e-23 80.0 14.9 0.00089 19.0 0.3 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 KFO95684.1 - 1.7e-17 62.1 6.9 0.012 15.7 0.0 7.5 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFO95684.1 - 5.1e-17 61.9 10.9 0.00051 20.3 0.2 5.9 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 KFO95684.1 - 7.9e-16 57.4 2.2 0.00075 20.1 0.0 7.4 3 2 5 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFO95684.1 - 1.1e-10 41.8 12.7 0.0023 18.4 0.1 5.6 4 2 3 7 7 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFO95684.1 - 1.6e-09 37.1 12.6 0.032 14.3 0.0 6.7 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFO95684.1 - 9e-09 35.8 8.8 0.31 11.7 0.0 6.3 6 3 1 7 7 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFO95684.1 - 6.1e-08 32.5 8.2 0.029 14.7 0.1 7.9 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFO95684.1 - 8.9e-07 29.2 13.9 2 9.2 0.4 7.5 8 1 0 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFO95684.1 - 8.2e-06 25.9 1.0 0.77 9.9 0.0 4.7 2 2 3 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFO95684.1 - 1.2e-05 24.6 4.4 1.6e-05 24.3 1.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFO95684.1 - 0.00025 20.8 5.7 0.22 11.4 0.6 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFO95684.1 - 0.00057 19.5 10.0 2.4 7.9 1.2 5.6 3 1 2 5 5 5 1 TPR repeat Coatomer_E PF04733.14 KFO95684.1 - 0.00065 19.2 6.3 0.014 14.8 0.6 2.9 1 1 2 3 3 3 2 Coatomer epsilon subunit ANAPC3 PF12895.7 KFO95684.1 - 0.0066 16.6 1.4 0.0066 16.6 1.4 4.1 2 2 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 PknG_TPR PF16918.5 KFO95684.1 - 0.012 14.4 0.0 0.025 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat NARP1 PF12569.8 KFO95684.1 - 0.02 13.8 4.9 0.17 10.7 0.0 2.9 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 PPR PF01535.20 KFO95684.1 - 0.13 12.5 0.1 45 4.6 0.1 3.9 4 0 0 4 4 4 0 PPR repeat DUF5112 PF17139.4 KFO95684.1 - 0.96 8.9 8.4 0.39 10.2 0.1 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF5112) Tyr-DNA_phospho PF06087.12 KFO95685.1 - 2.2e-137 458.5 0.0 2.7e-137 458.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Ion_trans_2 PF07885.16 KFO95686.1 - 5.1e-19 68.0 22.6 7.1e-15 54.7 8.3 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 KFO95686.1 - 0.025 13.8 13.3 0.028 13.6 4.6 2.2 2 0 0 2 2 2 0 Ion transport protein LPG_synthase_TM PF03706.13 KFO95686.1 - 0.073 12.6 1.4 0.13 11.8 1.4 1.4 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region AAA PF00004.29 KFO95687.1 - 5.7e-43 146.5 0.0 1.5e-42 145.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFO95687.1 - 5.6e-11 42.1 0.6 1e-10 41.2 0.6 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KFO95687.1 - 5.2e-10 39.1 0.2 1e-09 38.2 0.2 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KFO95687.1 - 5.1e-07 30.0 0.1 1.6e-06 28.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFO95687.1 - 1.2e-06 28.9 0.1 0.0011 19.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KFO95687.1 - 2.3e-05 23.7 0.0 4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KFO95687.1 - 5.3e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KFO95687.1 - 5.8e-05 23.1 0.4 0.00046 20.2 0.2 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFO95687.1 - 8.3e-05 23.0 0.2 0.0029 18.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 KFO95687.1 - 0.0021 17.8 0.0 0.0052 16.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 KFO95687.1 - 0.0039 17.4 0.0 0.008 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFO95687.1 - 0.005 17.4 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KFO95687.1 - 0.0056 16.5 0.1 0.1 12.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KFO95687.1 - 0.0062 15.9 0.1 0.26 10.6 0.0 2.5 2 1 1 3 3 2 1 KaiC AAA_28 PF13521.6 KFO95687.1 - 0.0063 16.8 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KFO95687.1 - 0.007 16.7 0.0 0.017 15.5 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 KFO95687.1 - 0.0078 15.8 0.3 0.34 10.4 0.1 2.4 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 KFO95687.1 - 0.015 14.6 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 KFO95687.1 - 0.015 15.4 0.0 0.038 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KFO95687.1 - 0.015 14.7 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Prot_ATP_OB_N PF17758.1 KFO95687.1 - 0.018 14.6 0.1 0.059 13.0 0.0 1.9 2 0 0 2 2 1 0 Proteasomal ATPase OB N-terminal domain PhoH PF02562.16 KFO95687.1 - 0.021 14.3 0.1 0.079 12.4 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 KFO95687.1 - 0.034 13.7 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_11 PF13086.6 KFO95687.1 - 0.037 13.8 0.3 0.99 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KFO95687.1 - 0.043 13.7 0.1 0.57 10.1 0.0 2.5 2 1 1 3 3 2 0 NACHT domain SKI PF01202.22 KFO95687.1 - 0.05 13.7 0.0 10 6.2 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase AAA_24 PF13479.6 KFO95687.1 - 0.058 13.1 1.3 0.089 12.5 0.2 1.9 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFO95687.1 - 0.064 13.0 0.2 0.16 11.7 0.2 1.6 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KFO95687.1 - 0.075 12.2 0.1 0.51 9.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain DivIC PF04977.15 KFO95687.1 - 0.079 12.7 0.1 2.2 8.1 0.3 2.3 2 0 0 2 2 2 0 Septum formation initiator ATPase_2 PF01637.18 KFO95687.1 - 0.09 12.7 0.6 1.7 8.5 0.0 2.8 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 KFO95687.1 - 0.099 13.2 0.0 0.41 11.2 0.0 2.1 2 0 0 2 2 2 0 ABC transporter TsaE PF02367.17 KFO95687.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 KFO95687.1 - 0.11 11.5 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 KFO95687.1 - 0.16 11.7 0.0 0.58 9.8 0.0 1.9 3 0 0 3 3 2 0 Sigma-54 interaction domain NRDE-2 PF08424.10 KFO95688.1 - 4e-107 358.1 2.2 4e-107 358.1 2.2 3.8 4 1 1 5 5 5 3 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KFO95688.1 - 4.2e-09 36.5 0.2 0.65 11.0 0.0 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFO95688.1 - 0.00033 21.1 0.2 2.1 8.9 0.1 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat Dsh_C PF12316.8 KFO95688.1 - 0.23 11.8 4.9 0.41 11.0 4.9 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal TPR_6 PF13174.6 KFO95688.1 - 1 10.2 2.5 57 4.7 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFO95688.1 - 1.3 9.3 6.5 4.2 7.7 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat AP3D1 PF06375.11 KFO95688.1 - 6.7 6.9 18.9 1.1 9.4 13.0 2.4 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 EF-hand_1 PF00036.32 KFO95689.1 - 9e-44 143.8 9.7 4.2e-10 38.4 0.4 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFO95689.1 - 3.8e-37 126.6 2.5 2.5e-19 69.5 0.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFO95689.1 - 4.5e-35 119.3 9.8 4.8e-15 55.1 0.3 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KFO95689.1 - 8.5e-32 106.4 4.9 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFO95689.1 - 1.1e-27 94.3 6.8 1.2e-06 27.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KFO95689.1 - 7.5e-16 58.2 0.2 2.3e-09 37.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KFO95689.1 - 2.5e-10 40.2 0.4 5.1e-05 23.2 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFO95689.1 - 3.7e-08 33.7 0.0 0.0036 17.6 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 KFO95689.1 - 2e-06 28.6 0.0 0.00083 20.2 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 KFO95689.1 - 1.1e-05 25.3 0.0 0.042 13.9 0.0 3.1 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KFO95689.1 - 1.5e-05 25.0 1.0 8.1e-05 22.6 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 KFO95689.1 - 0.00024 21.2 4.5 0.036 14.2 0.3 3.0 1 1 2 3 3 3 2 Dockerin type I domain DUF1103 PF06513.11 KFO95689.1 - 0.00071 19.3 1.4 0.00082 19.0 1.4 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.13 KFO95689.1 - 0.00084 19.3 0.8 0.83 9.6 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein DUF3349 PF11829.8 KFO95689.1 - 0.0013 19.5 0.5 2.3 9.1 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) DUF4497 PF14924.6 KFO95689.1 - 0.002 18.6 0.0 0.88 10.1 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) TerB PF05099.13 KFO95689.1 - 0.0024 17.9 0.8 0.57 10.1 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.16 KFO95689.1 - 0.0031 17.8 0.7 1.7 9.0 0.1 2.6 3 0 0 3 3 2 1 RNA polymerase Rpb4 DUF5580 PF17743.1 KFO95689.1 - 0.0056 15.3 0.0 0.0056 15.3 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 KFO95689.1 - 0.0074 16.2 0.8 0.39 10.6 0.2 2.2 1 1 1 2 2 2 1 SurA N-terminal domain Poly_export PF02563.16 KFO95689.1 - 0.011 15.9 0.1 0.56 10.5 0.0 3.0 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein EF-hand_14 PF17959.1 KFO95689.1 - 0.024 15.0 0.1 9.1 6.7 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain SurA_N_3 PF13624.6 KFO95689.1 - 0.043 13.6 0.4 0.56 10.0 0.2 2.0 1 1 1 2 2 2 0 SurA N-terminal domain Fe_hyd_lg_C PF02906.14 KFO95689.1 - 0.044 13.4 0.8 0.19 11.3 0.8 1.9 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain MotA_activ PF09114.10 KFO95689.1 - 0.052 13.7 0.3 0.95 9.6 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 KFO95689.1 - 0.077 12.2 0.2 6.8 5.8 0.1 2.4 1 1 1 2 2 2 0 Cache domain TetR_C_7 PF14246.6 KFO95689.1 - 0.083 12.9 0.1 7.2 6.7 0.0 2.8 2 1 1 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain RuvA_C PF07499.13 KFO95689.1 - 0.13 12.8 0.1 13 6.4 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain CMD PF02627.20 KFO95689.1 - 0.29 11.2 1.0 7 6.8 0.0 2.8 2 2 1 4 4 3 0 Carboxymuconolactone decarboxylase family SapB_1 PF05184.15 KFO95689.1 - 0.37 10.9 1.6 27 4.9 0.0 3.4 4 0 0 4 4 4 0 Saposin-like type B, region 1 Pkinase PF00069.25 KFO95690.1 - 5.6e-142 471.7 0.6 1.4e-72 244.3 0.2 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFO95690.1 - 1.2e-67 228.0 0.1 1.5e-33 116.2 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFO95690.1 - 2.1e-13 50.3 0.0 3.9e-06 26.4 0.0 3.0 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.14 KFO95690.1 - 3.8e-13 49.3 1.2 1.7e-09 37.3 0.1 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFO95690.1 - 1.1e-12 48.4 2.9 0.00011 22.3 0.0 4.1 2 2 2 4 4 4 3 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFO95690.1 - 3.5e-09 35.9 8.2 3.9e-06 25.9 0.1 3.1 3 0 0 3 3 3 2 Fungal protein kinase Haspin_kinase PF12330.8 KFO95690.1 - 5.3e-08 32.2 2.6 0.0041 16.1 0.4 2.5 2 0 0 2 2 2 2 Haspin like kinase domain Pkinase_C PF00433.24 KFO95690.1 - 8.9e-08 32.7 1.1 8.9e-08 32.7 1.1 2.1 2 0 0 2 2 1 1 Protein kinase C terminal domain RIO1 PF01163.22 KFO95690.1 - 6.1e-07 29.2 1.4 8.7e-05 22.2 0.2 2.5 2 0 0 2 2 2 2 RIO1 family FTA2 PF13095.6 KFO95690.1 - 2.1e-06 27.5 1.4 1.2 8.7 0.0 3.6 3 1 0 3 3 3 3 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 KFO95690.1 - 0.0012 18.4 1.6 0.014 15.0 0.0 2.9 3 0 0 3 3 3 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 KFO95690.1 - 0.016 14.7 1.2 0.39 10.2 0.1 2.8 2 1 1 3 3 3 0 PhoP regulatory network protein YrbL SR-25 PF10500.9 KFO95690.1 - 0.092 12.3 7.0 0.2 11.3 7.0 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CaMBD PF02888.16 KFO95690.1 - 0.33 11.2 2.1 5.8 7.2 0.4 2.4 2 0 0 2 2 2 0 Calmodulin binding domain DUF4392 PF14336.6 KFO95691.1 - 2.2e-117 391.7 0.0 3e-117 391.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) DUF1445 PF07286.12 KFO95691.1 - 1.7e-63 212.9 0.0 2.8e-63 212.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) SMK-1 PF04802.15 KFO95692.1 - 3e-80 268.6 7.1 3e-80 268.6 7.1 2.2 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 WH1 PF00568.23 KFO95692.1 - 0.0004 20.3 0.0 0.00092 19.1 0.0 1.6 1 0 0 1 1 1 1 WH1 domain Ran_BP1 PF00638.18 KFO95692.1 - 0.0054 17.0 0.0 0.025 14.9 0.0 2.2 1 0 0 1 1 1 1 RanBP1 domain Collagen PF01391.18 KFO95692.1 - 0.028 14.2 1.8 0.05 13.4 1.8 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) MAGE_N PF12440.8 KFO95692.1 - 0.67 10.7 4.4 1.3 9.7 1.6 2.3 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal C2 PF00168.30 KFO95693.1 - 2.6e-14 53.3 0.1 1.3e-08 35.0 0.0 2.3 2 0 0 2 2 2 2 C2 domain EGF_CA PF07645.15 KFO95694.1 - 2.7e-46 155.5 91.6 2.5e-11 43.6 8.3 7.4 8 0 0 8 8 8 6 Calcium-binding EGF domain cEGF PF12662.7 KFO95694.1 - 6.4e-37 125.1 53.8 5.2e-12 45.5 3.8 7.6 8 0 0 8 8 8 6 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFO95694.1 - 2.3e-23 82.2 96.8 6.6e-08 32.7 9.7 8.8 8 1 0 8 8 8 4 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 KFO95694.1 - 5.4e-13 48.9 69.9 1.1e-06 28.7 4.2 7.7 7 1 1 8 8 8 5 EGF domain hEGF PF12661.7 KFO95694.1 - 1.2e-05 25.7 72.2 0.013 16.1 5.1 8.9 7 2 0 7 7 7 4 Human growth factor-like EGF EGF PF00008.27 KFO95694.1 - 4.4e-05 23.7 87.6 0.0005 20.3 8.2 8.1 8 1 0 8 8 8 4 EGF-like domain TolA_bind_tri PF16331.5 KFO95695.1 - 0.00096 19.2 4.7 0.00096 19.2 4.7 21.8 12 6 10 23 23 23 2 TolA binding protein trimerisation DUF4407 PF14362.6 KFO95695.1 - 0.0018 17.7 11.7 0.0018 17.7 11.7 11.5 1 1 8 11 11 11 3 Domain of unknown function (DUF4407) Lipase_GDSL PF00657.22 KFO95695.1 - 0.024 14.6 11.1 0.95 9.4 1.1 6.2 3 2 2 5 5 5 0 GDSL-like Lipase/Acylhydrolase AP_endonuc_2 PF01261.24 KFO95695.1 - 2.3 7.6 4.4 53 3.2 1.4 3.4 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel NADH_oxidored PF08040.11 KFO95696.1 - 2.9e-35 119.8 0.1 3.1e-35 119.6 0.1 1.0 1 0 0 1 1 1 1 MNLL subunit Lactamase_B_6 PF16661.5 KFO95697.1 - 1.7e-63 213.6 0.0 4.5e-63 212.2 0.0 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KFO95697.1 - 2.5e-43 148.2 2.1 1.2e-42 146.0 0.0 2.2 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KFO95697.1 - 1.5e-20 73.5 0.0 3.3e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 KFO95697.1 - 2.8e-15 56.0 0.0 5.8e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 KFO95697.1 - 2.2e-06 27.8 0.0 4.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFO95697.1 - 8.8e-05 22.1 0.0 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 KFO95697.1 - 0.0018 17.5 0.0 0.018 14.3 0.0 2.4 2 1 0 2 2 2 1 Putative beta-lactamase-like family Na_Ca_ex PF01699.24 KFO95698.1 - 4.5e-53 179.3 39.4 9.4e-29 100.3 19.1 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Ac76 PF05814.11 KFO95698.1 - 5.2 7.2 19.2 0.47 10.5 2.0 3.3 3 0 0 3 3 3 0 Orf76 (Ac76) VPS9 PF02204.18 KFO95699.1 - 9.7e-27 93.2 1.2 1.4e-26 92.7 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain RA PF00788.23 KFO95699.1 - 2.2e-05 25.0 0.3 6.8e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain SH2 PF00017.24 KFO95699.1 - 0.013 15.6 0.0 0.12 12.5 0.0 2.6 2 0 0 2 2 2 0 SH2 domain SKICH PF17751.1 KFO95699.1 - 0.13 12.8 0.1 0.39 11.3 0.1 1.8 1 0 0 1 1 1 0 SKICH domain Peptidase_C13 PF01650.18 KFO95700.1 - 1.4e-117 391.7 1.4 2e-117 391.3 1.4 1.1 1 0 0 1 1 1 1 Peptidase C13 family DUF2675 PF11247.8 KFO95700.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2675) Golgin_A5 PF09787.9 KFO95701.1 - 8.3e-140 465.5 28.8 8.3e-140 465.5 28.8 3.5 2 1 2 4 4 4 1 Golgin subfamily A member 5 Spc7 PF08317.11 KFO95701.1 - 3.5e-05 22.8 93.1 0.0015 17.5 11.8 4.9 2 1 3 5 5 5 3 Spc7 kinetochore protein ATG16 PF08614.11 KFO95701.1 - 0.0025 18.1 17.4 0.0025 18.1 17.4 5.6 2 1 3 5 5 5 2 Autophagy protein 16 (ATG16) HIP1_clath_bdg PF16515.5 KFO95701.1 - 0.013 16.1 13.7 0.013 16.1 13.7 6.9 1 1 6 7 7 7 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PKcGMP_CC PF16808.5 KFO95701.1 - 0.013 15.3 1.0 0.013 15.3 1.0 5.0 6 0 0 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HOOK PF05622.12 KFO95701.1 - 0.15 10.2 91.9 0.062 11.4 31.5 2.5 2 1 1 3 3 3 0 HOOK protein TPR_MLP1_2 PF07926.12 KFO95701.1 - 1.9 8.5 105.8 0.13 12.3 32.2 6.1 3 2 3 6 6 6 0 TPR/MLP1/MLP2-like protein DUF2353 PF09789.9 KFO95701.1 - 3.7 6.8 69.1 0.25 10.6 28.0 2.8 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Ins134_P3_kin PF05770.11 KFO95703.1 - 1.8e-83 279.0 0.1 2.7e-83 278.4 0.1 1.2 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 KFO95703.1 - 6.9e-19 68.0 1.4 3.6e-18 65.7 0.6 2.4 2 0 0 2 2 2 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain RimK PF08443.11 KFO95703.1 - 0.00056 19.5 0.2 0.63 9.6 0.0 2.6 3 0 0 3 3 3 2 RimK-like ATP-grasp domain TMEM251 PF15190.6 KFO95704.1 - 5e-70 233.4 2.2 5.7e-70 233.3 2.2 1.0 1 0 0 1 1 1 1 Transmembrane protein 251 DUF4064 PF13273.6 KFO95704.1 - 0.0023 18.2 0.0 0.0034 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) AA_permease PF00324.21 KFO95704.1 - 0.013 14.1 0.2 0.017 13.7 0.2 1.2 1 0 0 1 1 1 0 Amino acid permease TctB PF07331.11 KFO95704.1 - 0.086 13.1 2.3 0.57 10.4 2.6 1.8 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF4131 PF13567.6 KFO95704.1 - 0.11 12.2 3.2 1.2 8.7 2.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PHD PF00628.29 KFO95705.1 - 0.00047 20.0 3.5 0.00047 20.0 3.5 3.2 4 0 0 4 4 4 1 PHD-finger BTB PF00651.31 KFO95706.1 - 3.2e-25 88.5 0.2 5.5e-14 52.3 0.0 3.5 1 1 0 2 2 2 2 BTB/POZ domain BACK PF07707.15 KFO95706.1 - 1.5e-10 41.1 0.2 4e-10 39.7 0.2 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch UNC-79 PF14776.6 KFO95707.1 - 3.2e-06 26.2 0.1 6.6e-06 25.2 0.1 1.5 1 1 1 2 2 2 1 Cation-channel complex subunit UNC-79 FAM181 PF15238.6 KFO95708.1 - 9.2e-85 284.9 6.9 1.1e-84 284.7 6.9 1.0 1 0 0 1 1 1 1 FAM181 Ank_2 PF12796.7 KFO95709.1 - 2.8e-66 220.1 23.0 8.7e-16 58.3 0.0 6.2 1 1 7 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFO95709.1 - 2.3e-48 161.9 8.5 1.6e-09 38.1 0.0 8.7 6 2 3 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFO95709.1 - 3.1e-45 146.9 10.5 0.00011 22.3 0.0 11.5 11 0 0 11 11 11 9 Ankyrin repeat Ank PF00023.30 KFO95709.1 - 1.1e-31 107.8 15.9 0.0031 17.9 0.0 11.0 9 2 2 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 KFO95709.1 - 2.2e-29 101.1 14.6 4e-09 36.6 0.3 9.3 2 1 9 11 11 11 9 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFO95709.1 - 1.8e-09 37.8 5.4 4e-09 36.7 5.4 1.6 1 0 0 1 1 1 1 SOCS box UIM PF02809.20 KFO95709.1 - 0.071 13.1 3.3 0.15 12.0 3.3 1.6 1 0 0 1 1 1 0 Ubiquitin interaction motif Serpin PF00079.20 KFO95710.1 - 2.2e-120 402.4 5.1 2.5e-120 402.2 5.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) FSH1 PF03959.13 KFO95710.1 - 0.0091 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF2179 PF10035.9 KFO95710.1 - 0.036 13.8 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2179) DUF5502 PF17606.2 KFO95710.1 - 0.069 13.9 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5502) Serpin PF00079.20 KFO95711.1 - 6.4e-105 351.5 3.8 1.2e-104 350.6 3.8 1.4 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFO95712.1 - 1.4e-112 376.7 1.8 1.5e-112 376.6 1.8 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFO95713.1 - 8.9e-113 377.4 0.2 9.9e-113 377.2 0.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF4198 PF10670.9 KFO95713.1 - 0.0014 19.1 0.0 0.0022 18.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4198) Homeodomain PF00046.29 KFO95714.1 - 2.3e-23 81.8 5.6 4.9e-23 80.7 5.6 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO95714.1 - 0.00085 19.2 0.1 0.0018 18.1 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain DUF3437 PF11919.8 KFO95714.1 - 0.14 12.1 2.3 0.99 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Ribonuclease_3 PF00636.26 KFO95715.1 - 6.4e-70 232.5 0.5 8.8e-44 148.4 0.0 3.4 3 1 0 3 3 3 2 Ribonuclease III domain PAZ PF02170.22 KFO95715.1 - 8e-40 135.8 0.7 5.2e-39 133.2 0.2 2.5 2 0 0 2 2 2 1 PAZ domain Ribonucleas_3_3 PF14622.6 KFO95715.1 - 6.8e-25 87.7 0.0 1.5e-16 60.7 0.0 3.8 3 1 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.14 KFO95715.1 - 1.7e-24 85.8 0.0 7.1e-24 83.8 0.0 2.2 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 KFO95715.1 - 3.9e-18 65.8 0.1 1.8e-17 63.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFO95715.1 - 4.3e-14 52.9 0.0 1.3e-13 51.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFO95715.1 - 8.6e-14 51.7 0.2 2e-13 50.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.9 KFO95715.1 - 0.01 15.1 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) dsrm PF00035.26 KFO95715.1 - 0.079 13.7 0.0 0.36 11.6 0.0 2.2 1 0 0 1 1 1 0 Double-stranded RNA binding motif CH PF00307.31 KFO95717.1 - 4.9e-37 126.4 0.2 5.5e-20 71.6 0.0 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFO95717.1 - 8.9e-07 28.7 0.0 0.014 15.2 0.0 2.5 2 0 0 2 2 2 2 CAMSAP CH domain RcsD_ABL PF16359.5 KFO95717.1 - 0.047 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 RcsD-ABL domain CH_2 PF06294.11 KFO95717.1 - 0.094 12.8 0.2 0.73 10.0 0.0 2.1 2 0 0 2 2 2 0 CH-like domain in sperm protein KASH PF10541.9 KFO95718.1 - 2.5e-25 88.5 6.9 5e-25 87.5 6.9 1.5 1 0 0 1 1 1 1 Nuclear envelope localisation domain Spectrin PF00435.21 KFO95718.1 - 2.6e-13 50.4 84.5 6e-07 29.9 5.2 9.0 6 1 3 9 9 9 5 Spectrin repeat FPP PF05911.11 KFO95718.1 - 0.00074 17.9 12.5 0.00074 17.9 12.5 3.1 2 1 1 3 3 3 1 Filament-like plant protein, long coiled-coil YCII PF03795.14 KFO95718.1 - 0.019 15.3 0.0 0.061 13.7 0.0 1.8 1 0 0 1 1 1 0 YCII-related domain CTD_bind PF04818.13 KFO95718.1 - 0.024 15.5 0.3 11 6.9 0.0 4.1 2 0 0 2 2 2 0 RNA polymerase II-binding domain. MCC-bdg_PDZ PF10506.9 KFO95718.1 - 0.26 11.3 10.6 8.7 6.4 0.1 5.4 4 0 0 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DP PF08781.10 KFO95718.1 - 0.94 9.4 12.4 1.5 8.7 3.2 3.7 3 0 0 3 3 3 0 Transcription factor DP FlaC_arch PF05377.11 KFO95718.1 - 1.7 9.1 17.0 83 3.7 0.0 7.3 6 1 0 6 6 6 0 Flagella accessory protein C (FlaC) DUF1515 PF07439.11 KFO95718.1 - 7.3 6.7 7.3 3.8 7.6 0.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1515) Glutaredoxin PF00462.24 KFO95719.1 - 7.5e-06 26.1 0.2 8e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin DUF2639 PF11121.8 KFO95719.1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2639) 7tm_1 PF00001.21 KFO95720.1 - 4.7e-51 173.6 31.8 6.4e-51 173.2 31.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ATG_C PF09333.11 KFO95721.1 - 4.9e-30 103.7 0.1 1.5e-29 102.2 0.1 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 KFO95721.1 - 3.3e-17 62.7 0.0 2.2e-16 60.0 0.0 2.3 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 KFO95721.1 - 2.4e-05 24.2 0.0 6.6e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal ATG2_CAD PF13329.6 KFO95721.1 - 0.00024 20.9 0.8 0.0025 17.6 0.8 2.4 1 1 0 1 1 1 1 Autophagy-related protein 2 CAD motif VPS13 PF16908.5 KFO95721.1 - 0.0013 18.6 0.0 0.013 15.3 0.0 2.5 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal FSA_C PF10479.9 KFO95721.1 - 0.11 10.6 0.0 0.23 9.6 0.0 1.4 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF727 PF05303.12 KFO95722.1 - 3.7e-32 110.5 0.0 4.8e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF727) ADK PF00406.22 KFO95723.1 - 1.6e-12 47.8 0.1 5.6e-09 36.3 0.1 3.0 1 1 0 1 1 1 1 Adenylate kinase Dpy-30 PF05186.13 KFO95723.1 - 3.6e-12 45.8 0.4 1.4e-11 43.8 0.1 2.3 2 0 0 2 2 2 1 Dpy-30 motif AAA_17 PF13207.6 KFO95723.1 - 2.8e-10 40.7 7.2 3.9e-09 37.0 0.3 3.4 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFO95723.1 - 2.1e-09 38.0 1.8 1.7e-08 35.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KFO95723.1 - 5.1e-06 26.9 0.0 2.3e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Hydin_ADK PF17213.3 KFO95723.1 - 1.1e-05 25.8 0.8 0.00015 22.1 0.0 2.4 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain AAA_16 PF13191.6 KFO95723.1 - 7.3e-05 23.2 0.2 0.00039 20.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KFO95723.1 - 0.00076 19.7 0.5 0.0017 18.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 KFO95723.1 - 0.0055 17.0 0.0 0.031 14.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFO95723.1 - 0.0056 17.1 0.0 0.015 15.7 0.0 1.7 1 0 0 1 1 1 1 RNA helicase RuvB_N PF05496.12 KFO95723.1 - 0.0057 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KFO95723.1 - 0.0057 16.6 0.1 0.021 14.8 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain NB-ARC PF00931.22 KFO95723.1 - 0.014 14.5 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.6 KFO95723.1 - 0.015 15.5 2.6 0.016 15.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 KFO95723.1 - 0.02 14.4 0.0 0.046 13.2 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_5 PF07728.14 KFO95723.1 - 0.039 14.0 0.0 0.09 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KFO95723.1 - 0.044 13.5 0.2 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 KFO95723.1 - 0.065 13.3 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 KFO95723.1 - 0.12 12.1 0.0 0.42 10.3 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 KFO95723.1 - 0.25 11.1 0.1 0.25 11.1 0.1 2.4 2 1 0 2 2 2 0 AAA domain DUF3987 PF13148.6 KFO95723.1 - 7.7 5.4 10.5 42 3.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) PAP_central PF04928.17 KFO95724.1 - 3.4e-116 386.5 0.0 3.4e-116 386.5 0.0 1.8 2 1 1 3 3 3 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KFO95724.1 - 3.5e-24 85.4 2.3 5.8e-19 68.4 0.0 3.1 2 1 1 3 3 3 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KFO95724.1 - 8.6e-14 51.6 0.1 2e-13 50.4 0.1 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Pox_Ag35 PF03286.14 KFO95724.1 - 2.1 8.1 9.1 1.3 8.8 5.9 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Pkinase PF00069.25 KFO95725.1 - 5.8e-15 55.4 0.0 8.1e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO95725.1 - 1.2e-08 34.5 0.0 4.8e-08 32.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFO95725.1 - 0.00016 20.6 1.9 0.0063 15.3 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase EcKinase PF02958.20 KFO95725.1 - 0.03 13.6 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase APH PF01636.23 KFO95725.1 - 0.041 13.8 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KFO95725.1 - 0.097 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Yae1_N PF09811.9 KFO95727.1 - 8.2e-15 54.2 50.4 1.8e+04 -15.2 50.4 5.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal zf-C2H2 PF00096.26 KFO95728.1 - 4.9e-26 89.7 53.8 5.3e-06 26.6 2.8 7.4 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO95728.1 - 3.2e-16 58.6 50.4 0.002 18.8 0.9 7.5 7 0 0 7 7 7 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFO95728.1 - 8.6e-16 57.6 44.1 2.9e-07 30.6 1.3 7.7 7 0 0 7 7 7 4 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFO95728.1 - 5.6e-05 22.8 34.4 9.2e-05 22.1 3.9 4.6 5 0 0 5 5 5 2 C2H2-type zinc-finger domain DUF3268 PF11672.8 KFO95728.1 - 0.00067 20.0 15.6 0.013 15.8 1.2 2.7 2 1 0 2 2 2 2 zinc-finger-containing domain zf-C2H2_7 PF15269.6 KFO95728.1 - 0.0097 16.0 13.0 0.36 10.9 0.5 3.7 3 0 0 3 3 3 2 Zinc-finger FYVE PF01363.21 KFO95728.1 - 0.014 15.6 25.1 0.21 11.8 0.5 5.3 5 0 0 5 5 5 0 FYVE zinc finger GAGA PF09237.11 KFO95728.1 - 0.073 12.9 7.9 1.7 8.5 0.6 3.0 2 1 0 2 2 2 0 GAGA factor Actin_micro PF17003.5 KFO95728.1 - 0.16 11.1 8.2 2.4 7.3 0.4 3.7 3 1 1 4 4 4 0 Putative actin-like family zf-FCS PF06467.14 KFO95728.1 - 1.4 8.9 13.1 3.1 7.8 0.1 4.1 4 0 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_jaz PF12171.8 KFO95728.1 - 2.8 8.3 44.6 0.95 9.8 1.9 6.2 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding DUF2256 PF10013.9 KFO95728.1 - 9 6.5 14.6 14 5.9 0.5 4.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) Rubis-subs-bind PF09273.11 KFO95729.1 - 5.8e-29 101.4 0.1 1.4e-28 100.2 0.1 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 KFO95729.1 - 4.2e-13 50.0 0.0 4.2e-13 50.0 0.0 2.0 2 1 0 2 2 2 1 SET domain Cyclin_N PF00134.23 KFO95730.1 - 6.8e-14 51.7 0.0 6.8e-14 51.7 0.0 2.3 3 0 0 3 3 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFO95730.1 - 0.003 17.6 7.8 0.027 14.5 7.8 2.2 1 1 0 1 1 1 1 Cyclin, C-terminal domain DAG_kinase_N PF14513.6 KFO95730.1 - 0.012 15.8 5.8 0.022 15.0 5.8 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus TFIIA PF03153.13 KFO95730.1 - 0.039 14.0 25.3 0.06 13.3 25.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 KFO95730.1 - 0.11 12.3 10.4 0.16 11.7 10.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PDZ_3 PF17815.1 KFO95730.1 - 0.17 11.7 0.0 0.17 11.7 0.0 1.6 2 0 0 2 2 1 0 PDZ domain AAR2 PF05282.11 KFO95730.1 - 0.51 9.7 6.4 0.72 9.2 6.4 1.1 1 0 0 1 1 1 0 AAR2 protein DUF966 PF06136.13 KFO95730.1 - 0.58 9.8 8.9 0.82 9.3 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Presenilin PF01080.17 KFO95730.1 - 0.78 8.4 11.7 1.1 7.9 11.7 1.1 1 0 0 1 1 1 0 Presenilin Lin-8 PF03353.15 KFO95730.1 - 3.1 7.3 16.1 4.5 6.7 16.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PAT1 PF09770.9 KFO95730.1 - 7.7 4.6 27.1 10 4.2 27.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 KFO95730.1 - 9.6 3.2 15.9 12 2.8 15.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CCDC85 PF10226.9 KFO95731.1 - 8.6e-95 315.9 13.9 2.2e-94 314.6 13.9 1.7 1 0 0 1 1 1 1 CCDC85 family AMH_N PF04709.12 KFO95731.1 - 0.0032 16.4 1.1 0.0057 15.6 1.1 1.3 1 0 0 1 1 1 1 Anti-Mullerian hormone, N terminal region DUF4577 PF15145.6 KFO95731.1 - 0.068 13.2 0.4 0.2 11.7 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) TSC22 PF01166.18 KFO95731.1 - 0.068 13.5 17.7 3.1 8.2 0.1 4.5 3 1 1 4 4 4 0 TSC-22/dip/bun family bZIP_1 PF00170.21 KFO95731.1 - 0.25 11.5 0.2 0.25 11.5 0.2 4.7 4 1 1 5 5 5 0 bZIP transcription factor Shugoshin_N PF07558.11 KFO95731.1 - 7.1 6.6 13.0 0.14 12.1 1.6 3.4 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Ets PF00178.22 KFO95732.1 - 1.6e-33 115.0 2.5 2.3e-33 114.5 2.5 1.2 1 0 0 1 1 1 1 Ets-domain Pkinase_Tyr PF07714.17 KFO95733.1 - 9.8e-81 270.8 0.0 1.3e-80 270.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.24 KFO95733.1 - 7e-54 180.7 0.1 8.4e-28 96.7 0.1 2.7 2 0 0 2 2 2 2 Receptor L domain Pkinase PF00069.25 KFO95733.1 - 1.2e-34 119.9 0.0 1.9e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 KFO95733.1 - 1.1e-19 70.6 3.9 1.3e-05 25.4 0.1 4.6 4 0 0 4 4 4 4 Fibronectin type III domain Furin-like PF00757.20 KFO95733.1 - 2.4e-18 66.4 16.7 2.9e-17 62.9 16.7 2.3 1 1 0 1 1 1 1 Furin-like cysteine rich region Kinase-like PF14531.6 KFO95733.1 - 0.025 13.9 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Furin-like_2 PF15913.5 KFO95733.1 - 0.072 13.3 7.7 0.075 13.2 5.5 2.2 1 1 1 2 2 2 0 Furin-like repeat, cysteine-rich Insulin_TMD PF17870.1 KFO95733.1 - 0.19 11.8 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment PRCC PF10253.9 KFO95734.1 - 8.1e-55 186.9 1.3 8.1e-55 186.9 1.3 2.1 2 0 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting Trypsin PF00089.26 KFO95735.1 - 1e-61 208.5 0.1 1.2e-61 208.4 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFO95735.1 - 2.5e-07 31.7 0.0 3.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFO95735.1 - 0.0002 21.7 0.0 0.00044 20.6 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin PF00089.26 KFO95736.1 - 6.6e-69 232.1 0.8 7.4e-69 231.9 0.8 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFO95736.1 - 0.00012 23.0 0.0 0.00019 22.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFO95736.1 - 0.00061 20.2 0.0 0.0014 19.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin PF00089.26 KFO95738.1 - 1e-11 45.1 1.0 1.1e-11 45.0 1.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 KFO95739.1 - 5.1e-74 248.8 2.1 5.7e-74 248.7 2.1 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFO95739.1 - 1.6e-05 25.3 0.2 4.5e-05 23.8 0.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 KFO95739.1 - 4.3e-05 24.4 0.0 7.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KFO95740.1 - 2e-15 57.2 0.7 2.2e-15 57.1 0.7 1.0 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 KFO95741.1 - 6.5e-16 58.8 0.8 7.1e-16 58.7 0.8 1.0 1 0 0 1 1 1 1 Trypsin AMP-binding PF00501.28 KFO95743.1 - 4.5e-44 150.7 0.0 6.4e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KFO95743.1 - 6e-10 38.9 2.4 1.4e-09 37.7 2.4 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Profilin PF00235.19 KFO95743.1 - 0.14 12.4 0.0 1.7 8.9 0.0 2.6 3 0 0 3 3 3 0 Profilin BRI3BP PF14965.6 KFO95744.1 - 2.5e-74 248.7 0.4 2.9e-74 248.5 0.4 1.0 1 0 0 1 1 1 1 Negative regulator of p53/TP53 CLZ PF16526.5 KFO95744.1 - 0.0084 16.5 0.1 0.054 13.9 0.1 2.0 2 0 0 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MgtE PF01769.16 KFO95744.1 - 0.11 12.9 3.6 0.15 12.4 3.6 1.3 1 0 0 1 1 1 0 Divalent cation transporter ubiquitin PF00240.23 KFO95745.1 - 2.7e-105 344.2 10.1 2.7e-34 116.8 0.3 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 KFO95745.1 - 4.2e-51 170.7 10.7 2.8e-16 59.1 0.4 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFO95745.1 - 2.3e-20 72.9 3.3 6.9e-05 23.2 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 KFO95745.1 - 1.1e-12 47.6 1.7 0.014 15.3 0.1 3.2 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KFO95745.1 - 7.2e-12 45.4 1.0 0.043 13.9 0.0 4.0 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KFO95745.1 - 1.5e-11 44.5 2.9 0.029 14.7 0.1 3.1 3 0 0 3 3 3 3 Ubiquitin-like domain DUF2407 PF10302.9 KFO95745.1 - 2.9e-09 37.4 0.1 0.37 11.4 0.0 3.2 1 1 1 3 3 3 3 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 KFO95745.1 - 1.7e-06 28.0 0.0 1.6 8.5 0.0 3.1 1 1 2 3 3 3 3 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 KFO95745.1 - 4e-06 26.8 14.1 17 5.6 0.0 6.0 6 0 0 6 6 6 0 Ubiquitin-like domain DUF2870 PF11069.8 KFO95745.1 - 0.00024 21.4 0.1 20 5.7 0.0 3.8 3 3 0 3 3 3 0 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.14 KFO95745.1 - 0.0007 19.0 0.1 1.2 8.5 0.0 2.3 2 0 0 2 2 2 2 RNA methyltransferase RBD PF02196.15 KFO95745.1 - 0.00075 19.5 0.0 22 5.2 0.0 3.3 3 0 0 3 3 3 0 Raf-like Ras-binding domain DUF3861 PF12977.7 KFO95745.1 - 0.0017 18.5 0.2 26 5.1 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) UDP-g_GGTase PF06427.11 KFO95745.1 - 0.0018 18.4 2.0 3.4 7.8 0.0 3.2 4 0 0 4 4 3 2 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 KFO95745.1 - 0.0077 15.7 0.0 14 5.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF969) FlgD_ig PF13860.6 KFO95745.1 - 0.019 14.8 2.4 39 4.2 0.1 3.4 3 0 0 3 3 3 0 FlgD Ig-like domain Big_7 PF17957.1 KFO95745.1 - 0.02 15.6 0.0 89 4.0 0.0 3.1 3 0 0 3 3 3 0 Bacterial Ig domain GDYXXLXY PF14345.6 KFO95745.1 - 0.052 13.3 0.1 75 3.1 0.0 3.3 3 0 0 3 3 3 0 GDYXXLXY protein CorA PF01544.18 KFO95745.1 - 0.058 12.7 0.1 51 3.0 0.0 3.0 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein ORF11CD3 PF10549.9 KFO95745.1 - 0.062 13.4 0.0 61 3.8 0.0 3.7 3 0 0 3 3 3 0 ORF11CD3 domain TraK PF06586.11 KFO95745.1 - 0.068 12.9 0.1 59 3.2 0.0 3.1 3 0 0 3 3 3 0 TraK protein Phage_sheath_1N PF17481.2 KFO95745.1 - 0.069 13.6 1.7 22 5.6 0.3 3.0 1 1 0 2 2 2 0 Phage tail sheath protein beta-sandwich domain ProRS-C_2 PF09181.10 KFO95745.1 - 0.084 13.0 1.1 88 3.3 0.0 3.1 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal DMA PF03474.14 KFO95745.1 - 0.42 10.3 1.7 1.1e+02 2.5 0.0 3.3 3 0 0 3 3 3 0 DMRTA motif PI3K_p85B PF02192.16 KFO95745.1 - 1.3 8.8 3.4 1.1e+02 2.6 0.1 3.2 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain DUF4616 PF15394.6 KFO95746.1 - 0.32 9.9 0.5 10 4.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4616) CD36 PF01130.21 KFO95747.1 - 3.7e-142 474.2 2.7 4.2e-142 474.0 2.7 1.0 1 0 0 1 1 1 1 CD36 family DUF3915 PF13054.6 KFO95748.1 - 0.27 11.2 2.9 0.66 10.0 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) FAM101 PF15068.6 KFO95749.1 - 3e-89 298.4 0.0 3.4e-89 298.3 0.0 1.0 1 0 0 1 1 1 1 FAM101 family CCDC92 PF14916.6 KFO95750.1 - 2.8e-23 81.4 8.4 3.4e-22 78.0 1.7 2.7 2 0 0 2 2 2 2 Coiled-coil domain of unknown function Angiomotin_C PF12240.8 KFO95750.1 - 0.0016 18.1 8.9 0.0024 17.5 7.9 1.7 1 1 1 2 2 2 1 Angiomotin C terminal Sigma54_DBD PF04552.13 KFO95750.1 - 0.0019 17.9 1.9 0.0033 17.1 1.9 1.4 1 0 0 1 1 1 1 Sigma-54, DNA binding domain CENP-F_leu_zip PF10473.9 KFO95750.1 - 0.0092 16.0 22.6 0.35 10.9 0.6 2.4 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Exonuc_VII_L PF02601.15 KFO95750.1 - 0.059 12.9 7.9 0.088 12.4 7.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4618 PF15397.6 KFO95750.1 - 0.17 11.3 18.7 0.33 10.3 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF3584 PF12128.8 KFO95750.1 - 0.19 9.2 13.4 0.25 8.8 13.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Phage_GP20 PF06810.11 KFO95750.1 - 0.57 10.0 16.6 2.8 7.7 0.2 2.8 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF4407 PF14362.6 KFO95750.1 - 0.63 9.3 8.4 1.4 8.2 8.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 KFO95750.1 - 0.8 9.8 23.0 0.32 11.1 0.4 3.1 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 KFO95750.1 - 0.98 8.4 18.6 0.55 9.3 13.2 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Nup54 PF13874.6 KFO95750.1 - 1.4 9.0 16.5 0.067 13.3 6.1 2.3 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 MscS_porin PF12795.7 KFO95750.1 - 2.1 7.8 18.4 11 5.4 18.5 1.9 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Fez1 PF06818.15 KFO95750.1 - 2.2 8.7 18.3 1.5 9.2 14.5 2.2 1 1 1 2 2 2 0 Fez1 FlxA PF14282.6 KFO95750.1 - 2.4 8.2 15.8 1 9.4 3.6 3.4 1 1 1 3 3 3 0 FlxA-like protein V_ATPase_I PF01496.19 KFO95750.1 - 3.3 5.5 8.4 4.3 5.1 8.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Syntaxin-6_N PF09177.11 KFO95750.1 - 4.1 8.0 10.5 1.6e+02 2.9 10.5 2.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Golgin_A5 PF09787.9 KFO95750.1 - 5.6 6.3 18.9 6.2 6.2 0.6 2.1 1 1 0 1 1 1 0 Golgin subfamily A member 5 Baculo_PEP_C PF04513.12 KFO95750.1 - 5.7 7.0 8.3 2.3 8.3 2.1 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus KxDL PF10241.9 KFO95750.1 - 6.6 7.1 16.9 1.7 8.9 8.1 2.7 2 1 1 3 3 3 0 Uncharacterized conserved protein UPF0242 PF06785.11 KFO95750.1 - 6.8 6.7 20.4 5.3 7.1 0.6 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 KFO95750.1 - 9.2 6.1 11.0 3.9 7.3 4.7 2.9 2 2 0 2 2 2 0 Septum formation initiator FlaC_arch PF05377.11 KFO95750.1 - 9.5 6.7 9.8 13 6.3 2.6 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.19 KFO95751.1 - 9.4e-287 953.3 1.3 1.1e-286 953.1 1.3 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.9 KFO95751.1 - 0.032 14.2 5.5 0.043 13.8 2.8 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DHR10 PF18595.1 KFO95751.1 - 0.93 9.6 7.3 0.23 11.5 2.2 2.4 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain DUF4404 PF14357.6 KFO95751.1 - 0.96 10.1 4.1 7.2 7.3 2.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) IFP_35_N PF07334.13 KFO95751.1 - 1.4 9.0 4.8 3.1 8.0 4.8 1.5 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF1619 PF07773.11 KFO95752.1 - 1.1e-57 196.4 2.5 1.1e-55 189.9 2.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1619) Tfb4 PF03850.14 KFO95753.1 - 4.4e-101 338.0 0.5 5.1e-101 337.8 0.5 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Baculo_IE-1 PF05290.11 KFO95753.1 - 1.9 8.4 8.4 0.64 10.0 4.7 2.0 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) IF-2B PF01008.17 KFO95754.1 - 5.2e-77 258.8 0.0 5.9e-77 258.6 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family SPC12 PF06645.13 KFO95754.1 - 0.083 13.0 0.1 0.41 10.8 0.0 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DEAD PF00270.29 KFO95755.1 - 1.2e-40 139.2 0.0 2.4e-40 138.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFO95755.1 - 4.6e-23 81.7 0.0 2.4e-21 76.1 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFO95755.1 - 2.9e-22 78.7 0.7 8.4e-22 77.2 0.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KFO95755.1 - 1.6e-06 28.2 3.6 5e-06 26.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KFO95755.1 - 0.0072 16.6 0.2 0.023 15.0 0.2 2.0 1 1 0 1 1 1 1 AAA domain SBF_like PF13593.6 KFO95755.1 - 0.022 14.1 0.0 0.032 13.5 0.0 1.1 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) SHOCT PF09851.9 KFO95755.1 - 0.033 13.9 0.3 0.033 13.9 0.3 2.9 3 0 0 3 3 3 0 Short C-terminal domain Helicase_C_2 PF13307.6 KFO95755.1 - 0.049 13.8 1.7 0.34 11.1 0.0 2.5 2 0 0 2 2 2 0 Helicase C-terminal domain EMP24_GP25L PF01105.24 KFO95756.1 - 1.3e-39 136.1 0.1 1.5e-39 135.8 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TerD PF02342.18 KFO95756.1 - 0.00057 19.4 0.2 0.00069 19.1 0.2 1.1 1 0 0 1 1 1 1 TerD domain Innexin PF00876.18 KFO95756.1 - 0.037 13.3 0.3 0.042 13.1 0.3 1.1 1 0 0 1 1 1 0 Innexin SdrD_B PF17210.3 KFO95756.1 - 0.041 14.1 0.3 0.1 12.8 0.3 1.7 1 1 0 1 1 1 0 SdrD B-like domain DUF1104 PF06518.11 KFO95756.1 - 0.13 12.7 1.6 0.24 11.8 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) RILP PF11461.8 KFO95757.1 - 2e-21 76.0 2.1 2e-21 76.0 2.1 2.9 2 1 0 2 2 2 1 Rab interacting lysosomal protein Jnk-SapK_ap_N PF09744.9 KFO95757.1 - 1.8e-13 51.0 6.5 1.8e-13 51.0 6.5 3.4 2 1 1 3 3 2 1 JNK_SAPK-associated protein-1 YflT PF11181.8 KFO95757.1 - 0.014 15.9 1.7 0.079 13.5 1.7 2.3 1 1 0 1 1 1 0 Heat induced stress protein YflT sCache_like PF16736.5 KFO95757.1 - 0.017 15.2 3.1 0.017 15.2 3.1 2.7 1 1 2 3 3 3 0 Single Cache-like Leu_zip PF15294.6 KFO95757.1 - 0.022 14.3 24.3 0.017 14.7 13.3 2.5 1 1 1 2 2 2 0 Leucine zipper Spc42p PF11544.8 KFO95757.1 - 0.038 14.0 0.8 0.038 14.0 0.8 4.5 4 1 0 5 5 5 0 Spindle pole body component Spc42p TSC22 PF01166.18 KFO95757.1 - 0.067 13.5 0.8 0.067 13.5 0.8 4.3 4 1 1 5 5 4 0 TSC-22/dip/bun family FGAR-AT_linker PF18072.1 KFO95757.1 - 0.09 13.3 0.8 25 5.5 0.0 3.4 2 1 1 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase linker domain Wtap PF17098.5 KFO95757.1 - 0.098 12.6 18.1 0.18 11.7 1.6 3.3 1 1 1 3 3 3 0 WTAP/Mum2p family DUF3450 PF11932.8 KFO95757.1 - 0.12 11.6 17.0 0.59 9.4 4.2 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4407 PF14362.6 KFO95757.1 - 0.64 9.3 15.4 4.7 6.5 15.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SOGA PF11365.8 KFO95757.1 - 1.1 10.5 26.3 0.28 12.3 7.4 3.5 1 1 1 3 3 3 0 Protein SOGA HrpB7 PF09486.10 KFO95757.1 - 1.1 9.7 13.5 2.6 8.4 1.0 2.8 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Spectrin PF00435.21 KFO95757.1 - 1.9 9.0 19.7 0.24 11.9 8.2 3.0 2 1 1 3 3 3 0 Spectrin repeat Metal_resist PF13801.6 KFO95757.1 - 6.8 6.9 8.6 15 5.8 0.8 3.2 3 0 0 3 3 3 0 Heavy-metal resistance RRM_1 PF00076.22 KFO95758.1 - 1.7e-17 63.0 0.1 2.9e-17 62.3 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_ligase_IV PF11411.8 KFO95758.1 - 0.064 13.4 0.0 0.71 10.0 0.0 2.2 2 0 0 2 2 2 0 DNA ligase IV SET PF00856.28 KFO95759.1 - 6.8e-20 72.1 1.4 6e-19 69.0 0.1 2.4 2 1 0 2 2 2 1 SET domain SRP-alpha_N PF04086.13 KFO95759.1 - 0.16 11.8 8.7 0.21 11.5 8.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CDK2AP PF09806.9 KFO95760.1 - 1.3e-09 38.5 0.0 1.7e-09 38.1 0.0 1.4 1 1 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein RF-1 PF00472.20 KFO95761.1 - 3.5e-23 81.7 3.1 4.3e-23 81.5 3.1 1.1 1 0 0 1 1 1 1 RF-1 domain DUF2098 PF09871.9 KFO95761.1 - 0.017 15.4 1.1 0.022 15.1 1.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) Tropomyosin_1 PF12718.7 KFO95762.1 - 0.00022 21.4 34.9 0.039 14.1 19.8 3.5 1 1 1 2 2 2 2 Tropomyosin like GAS PF13851.6 KFO95762.1 - 0.0011 18.4 33.1 0.098 12.0 13.7 3.0 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding EzrA PF06160.12 KFO95762.1 - 0.0015 16.8 19.3 0.0029 15.9 19.3 1.4 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Tup_N PF08581.10 KFO95762.1 - 0.0066 16.7 21.8 0.17 12.2 0.5 4.2 2 1 1 3 3 3 1 Tup N-terminal KASH_CCD PF14662.6 KFO95762.1 - 0.014 15.3 34.2 0.17 11.7 19.3 3.5 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH Lebercilin PF15619.6 KFO95762.1 - 0.053 13.2 38.6 0.12 12.0 16.1 3.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Laminin_II PF06009.12 KFO95762.1 - 0.06 13.4 20.7 0.17 11.9 4.4 3.3 1 1 1 2 2 2 0 Laminin Domain II Spc7 PF08317.11 KFO95762.1 - 0.067 12.1 30.6 0.096 11.6 18.6 2.7 1 1 1 2 2 2 0 Spc7 kinetochore protein Filament PF00038.21 KFO95762.1 - 0.073 12.7 31.4 0.28 10.7 11.6 3.6 1 1 2 3 3 3 0 Intermediate filament protein DUF1664 PF07889.12 KFO95762.1 - 0.099 12.7 16.9 0.053 13.6 4.8 3.4 2 1 1 4 4 3 0 Protein of unknown function (DUF1664) ADIP PF11559.8 KFO95762.1 - 0.15 12.2 43.2 0.12 12.5 14.2 4.7 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Laminin_I PF06008.14 KFO95762.1 - 0.4 10.3 27.7 0.083 12.6 22.7 2.4 2 1 0 2 2 1 0 Laminin Domain I RPW8 PF05659.11 KFO95762.1 - 0.49 10.1 10.3 1.3 8.7 3.1 3.3 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 SHE3 PF17078.5 KFO95762.1 - 0.5 10.0 27.7 2.4 7.8 9.2 3.5 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 DASH_Dad2 PF08654.10 KFO95762.1 - 0.64 10.5 10.5 0.69 10.4 4.9 3.7 2 1 0 3 3 3 0 DASH complex subunit Dad2 Tropomyosin PF00261.20 KFO95762.1 - 0.68 9.3 35.6 0.34 10.2 3.9 3.4 2 1 1 3 3 2 0 Tropomyosin BLOC1_2 PF10046.9 KFO95762.1 - 0.99 9.7 22.2 1.8 8.9 2.5 4.0 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.9 KFO95762.1 - 1.4 7.9 28.5 2 7.4 13.8 2.8 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 KFO95762.1 - 1.6 8.0 24.6 99 2.1 1.1 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF745 PF05335.13 KFO95762.1 - 2.2 8.0 16.8 7.1 6.3 15.3 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF745) AAA_27 PF13514.6 KFO95762.1 - 2.3 7.8 9.7 0.62 9.6 0.6 2.5 1 1 1 2 2 2 0 AAA domain Fib_alpha PF08702.10 KFO95762.1 - 2.3 8.4 25.5 0.52 10.5 10.1 4.1 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Rab5-bind PF09311.11 KFO95762.1 - 3.9 6.8 31.7 2.7 7.3 14.6 3.2 2 1 1 3 3 3 0 Rabaptin-like protein DUF3450 PF11932.8 KFO95762.1 - 5.3 6.3 22.8 2.7 7.2 8.4 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Seryl_tRNA_N PF02403.22 KFO95762.1 - 5.8 7.2 29.3 10 6.4 12.0 4.2 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain BST2 PF16716.5 KFO95762.1 - 6.2 7.5 27.3 5.4 7.7 6.6 4.7 1 1 2 4 4 4 0 Bone marrow stromal antigen 2 Gp-FAR-1 PF05823.12 KFO95762.1 - 6.7 7.1 17.0 0.69 10.3 10.1 3.0 2 1 0 3 3 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Syntaxin-6_N PF09177.11 KFO95762.1 - 7.1 7.3 22.5 12 6.5 2.5 4.5 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Sec34 PF04136.15 KFO95762.1 - 7.9 6.3 20.8 0.03 14.2 5.8 3.4 2 1 1 3 3 3 0 Sec34-like family TRPM_tetra PF16519.5 KFO95762.1 - 8.6 6.6 8.4 5.7 7.1 1.3 2.8 2 0 0 2 2 2 0 Tetramerisation domain of TRPM SR-25 PF10500.9 KFO95763.1 - 6.4e-85 284.4 75.9 1.2e-84 283.4 75.9 1.4 1 1 0 1 1 1 1 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 KFO95763.1 - 0.46 9.0 32.7 0.65 8.5 32.7 1.3 1 0 0 1 1 1 0 Macoilin family Integrase_H2C2 PF17921.1 KFO95765.1 - 3.5e-17 62.2 0.6 4.9e-17 61.8 0.6 1.2 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFO95765.1 - 2.2e-06 27.8 0.5 4.2e-06 26.9 0.5 1.4 1 0 0 1 1 1 1 H2C2 zinc finger ABC_membrane PF00664.23 KFO95766.1 - 1.3e-57 195.6 16.3 2.5e-57 194.6 16.3 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFO95766.1 - 2.9e-34 118.5 0.0 6e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFO95766.1 - 7.4e-11 41.9 0.2 2.9e-07 30.2 0.1 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFO95766.1 - 2.7e-05 24.6 0.0 7.4e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFO95766.1 - 0.00023 21.4 0.0 0.00098 19.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KFO95766.1 - 0.00025 21.0 0.0 0.0006 19.8 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase ABC_membrane_3 PF13748.6 KFO95766.1 - 0.00099 18.4 4.1 0.002 17.4 4.1 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_29 PF13555.6 KFO95766.1 - 0.0058 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MCU PF04678.13 KFO95766.1 - 0.013 15.7 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF4191 PF13829.6 KFO95766.1 - 0.058 12.7 0.2 0.058 12.7 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) AAA_30 PF13604.6 KFO95766.1 - 0.067 12.9 0.0 0.24 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KFO95766.1 - 0.13 12.5 0.7 2 8.7 0.7 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 KFO95766.1 - 0.23 12.0 0.8 9.9 6.7 0.0 2.7 2 1 1 3 3 2 0 AAA domain MFS_MOT1 PF16983.5 KFO95766.1 - 2.9 8.3 8.8 1.1 9.7 0.7 3.0 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily Mod_r PF07200.13 KFO95767.1 - 8.9e-33 113.4 8.1 1.1e-32 113.2 8.1 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein TBK1_CCD1 PF18394.1 KFO95767.1 - 0.019 14.6 0.7 0.024 14.2 0.7 1.1 1 0 0 1 1 1 0 TANK-binding kinase 1 coiled-coil domain 1 7TMR-HDED PF07697.11 KFO95767.1 - 0.12 12.5 2.6 0.14 12.2 2.6 1.1 1 0 0 1 1 1 0 7TM-HD extracellular Cortex-I_coil PF09304.10 KFO95767.1 - 0.62 10.3 7.8 2.2 8.5 7.8 1.8 1 1 0 1 1 1 0 Cortexillin I, coiled coil ANTH PF07651.16 KFO95768.1 - 1.9e-76 256.7 0.1 1.9e-76 256.7 0.1 2.9 3 1 0 3 3 3 1 ANTH domain HIP1_clath_bdg PF16515.5 KFO95768.1 - 1e-29 103.0 22.8 1e-29 103.0 22.8 6.0 5 2 1 6 6 6 1 Clathrin-binding domain of Huntingtin-interacting protein 1 I_LWEQ PF01608.17 KFO95768.1 - 1.1e-21 77.7 1.6 1.1e-21 77.7 1.6 5.0 3 1 2 5 5 5 1 I/LWEQ domain Golgin_A5 PF09787.9 KFO95768.1 - 0.46 9.9 73.1 0.17 11.4 13.9 4.2 2 1 2 4 4 4 0 Golgin subfamily A member 5 DUF3584 PF12128.8 KFO95768.1 - 0.66 7.4 61.2 0.016 12.7 52.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) HAP1_N PF04849.13 KFO95769.1 - 0.00067 19.0 47.9 0.00071 18.9 11.6 2.9 1 1 2 3 3 3 2 HAP1 N-terminal conserved region UFD1 PF03152.14 KFO95769.1 - 0.02 14.4 5.1 0.18 11.3 0.7 2.5 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 DUF1664 PF07889.12 KFO95769.1 - 0.43 10.6 25.3 0.056 13.5 5.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4201 PF13870.6 KFO95769.1 - 0.94 9.2 47.3 4.4 7.0 20.8 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Ax_dynein_light PF10211.9 KFO95769.1 - 4.7 7.1 39.7 0.21 11.5 13.8 3.7 1 1 2 3 3 3 0 Axonemal dynein light chain SUI1 PF01253.22 KFO95770.1 - 4e-17 62.5 0.1 7e-17 61.7 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 ATP_bind_1 PF03029.17 KFO95771.1 - 4.9e-91 304.8 0.4 5.6e-91 304.6 0.4 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 KFO95771.1 - 0.0067 16.2 0.0 0.039 13.8 0.0 2.1 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 KFO95771.1 - 0.051 12.6 0.0 0.091 11.7 0.0 1.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_31 PF13614.6 KFO95771.1 - 0.063 13.2 0.0 2.9 7.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain P21-Arc PF04062.14 KFO95772.1 - 8.2e-82 273.4 0.2 9.1e-82 273.3 0.2 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit TPR_2 PF07719.17 KFO95773.1 - 5e-13 48.1 14.6 0.059 13.5 0.0 8.6 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFO95773.1 - 7.2e-12 45.1 2.7 0.33 11.9 0.0 7.8 7 1 2 9 9 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFO95773.1 - 1.8e-09 38.0 14.8 0.0015 19.0 0.1 7.0 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFO95773.1 - 8.1e-09 36.0 0.5 0.0012 19.5 0.1 5.6 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFO95773.1 - 8.5e-08 31.8 6.3 0.5 10.7 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFO95773.1 - 1.9e-06 27.4 14.4 0.091 12.6 0.0 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO95773.1 - 2e-05 24.7 15.0 0.083 13.1 0.5 6.3 6 1 1 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KFO95773.1 - 2.7e-05 23.9 6.9 0.14 12.3 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFO95773.1 - 0.00018 21.9 9.1 3.9 8.3 0.0 6.8 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFO95773.1 - 0.00036 20.2 12.8 0.039 13.7 0.0 6.4 6 1 1 7 7 7 1 TPR repeat TPR_21 PF09976.9 KFO95773.1 - 0.0005 19.8 1.7 0.0005 19.8 1.7 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat-like domain ChAPs PF09295.10 KFO95773.1 - 0.0038 16.3 3.0 0.4 9.6 0.1 2.5 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) FeoC PF09012.10 KFO95773.1 - 0.004 17.2 0.1 0.012 15.7 0.1 1.8 1 0 0 1 1 1 1 FeoC like transcriptional regulator TPR_17 PF13431.6 KFO95773.1 - 0.02 15.2 6.9 72 4.1 0.0 6.6 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_20 PF14561.6 KFO95773.1 - 0.055 13.8 5.7 3 8.2 0.3 4.8 4 2 1 5 5 5 0 Tetratricopeptide repeat E1-E2_ATPase PF00122.20 KFO95774.1 - 2.2e-55 187.0 6.7 2.5e-54 183.5 0.3 2.9 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFO95774.1 - 1.3e-45 155.3 2.4 1.3e-45 155.3 2.4 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KFO95774.1 - 9.2e-21 73.7 0.3 1.7e-20 72.8 0.3 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFO95774.1 - 8.1e-18 65.5 0.1 2.4e-14 54.1 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFO95774.1 - 3.6e-17 61.8 1.4 2.2e-16 59.3 0.2 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFO95774.1 - 7.3e-06 25.9 0.6 1.7e-05 24.7 0.6 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFO95774.1 - 0.001 19.5 0.1 0.0058 17.1 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase IFT81_CH PF18383.1 KFO95775.1 - 8.8e-50 168.1 0.1 8.8e-50 168.1 0.1 2.9 3 0 0 3 3 3 1 Intraflagellar transport 81 calponin homology domain Spc7 PF08317.11 KFO95775.1 - 0.0027 16.6 17.0 0.0027 16.6 17.0 5.1 1 1 5 6 6 6 3 Spc7 kinetochore protein DUF948 PF06103.11 KFO95775.1 - 2.6 8.4 16.7 0.33 11.2 0.3 4.5 5 2 0 5 5 5 0 Bacterial protein of unknown function (DUF948) Osmo_CC PF08946.10 KFO95775.1 - 3.8 7.8 20.3 1.4 9.2 0.6 6.3 5 0 0 5 5 5 0 Osmosensory transporter coiled coil P2X_receptor PF00864.19 KFO95777.1 - 9.6e-173 574.4 3.0 1.1e-172 574.2 3.0 1.0 1 0 0 1 1 1 1 ATP P2X receptor Pkinase PF00069.25 KFO95778.1 - 3.8e-65 219.9 0.0 2.6e-64 217.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO95778.1 - 5.4e-34 117.7 0.0 4.8e-32 111.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFO95778.1 - 2.3e-08 33.7 0.0 3.4e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFO95778.1 - 5.1e-05 22.2 0.0 7.7e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KFO95778.1 - 0.0078 15.8 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KFO95778.1 - 0.029 14.3 0.2 0.95 9.3 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFO95778.1 - 0.054 12.5 0.1 2.2 7.2 0.0 2.3 2 0 0 2 2 2 0 Seadornavirus VP7 ANAPC5 PF12862.7 KFO95779.1 - 4.7e-31 106.7 2.4 4.7e-31 106.7 2.4 4.1 5 1 0 5 5 4 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 KFO95779.1 - 2e-09 37.6 10.9 0.00013 22.1 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFO95779.1 - 2.3e-05 24.8 9.0 0.15 12.6 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFO95779.1 - 0.00029 20.6 6.7 0.019 14.8 2.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFO95779.1 - 0.0003 20.6 6.8 0.09 12.8 0.8 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFO95779.1 - 0.0052 16.8 14.1 0.7 10.2 2.2 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFO95779.1 - 0.018 15.8 8.6 58 4.9 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat PriA_C PF18074.1 KFO95779.1 - 0.3 11.9 2.1 0.72 10.7 0.4 2.7 2 1 0 2 2 1 0 Primosomal protein N C-terminal domain TPR_8 PF13181.6 KFO95779.1 - 0.66 10.3 7.5 23 5.5 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFO95779.1 - 0.84 9.6 7.4 2.2 8.2 1.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFO95779.1 - 1.9 9.4 7.8 1.2 10.0 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFO95779.1 - 7.4 7.2 7.0 96 3.7 0.4 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat PHD_4 PF16866.5 KFO95780.1 - 1e-26 92.8 9.6 1e-26 92.8 9.6 2.6 2 0 0 2 2 1 1 PHD-finger zf-CXXC PF02008.20 KFO95780.1 - 1.4e-14 53.8 21.5 1.4e-14 53.8 21.5 3.0 2 0 0 2 2 2 1 CXXC zinc finger domain F-box PF00646.33 KFO95780.1 - 2.1e-13 49.7 6.9 1.1e-12 47.4 1.7 2.8 2 0 0 2 2 2 1 F-box domain JHD PF17811.1 KFO95780.1 - 9.4e-11 42.2 7.9 2.4e-10 40.9 0.1 3.3 3 0 0 3 3 3 1 Jumonji helical domain F-box-like PF12937.7 KFO95780.1 - 7.3e-09 35.4 5.8 2e-08 34.0 5.8 1.8 1 0 0 1 1 1 1 F-box-like Cupin_8 PF13621.6 KFO95780.1 - 7.4e-07 29.1 2.5 2.6e-06 27.3 0.0 2.7 2 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 KFO95780.1 - 6.5e-05 23.3 0.3 6.5e-05 23.3 0.3 3.6 4 1 0 4 4 3 1 JmjC domain, hydroxylase LRR_6 PF13516.6 KFO95780.1 - 0.00066 19.5 8.4 31 5.0 0.3 7.1 8 0 0 8 8 8 0 Leucine Rich repeat PHD PF00628.29 KFO95780.1 - 0.0062 16.4 8.1 0.0062 16.4 8.1 3.0 2 0 0 2 2 1 1 PHD-finger LRR_4 PF12799.7 KFO95780.1 - 0.11 13.0 7.9 6.2 7.4 0.4 4.2 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFO95780.1 - 0.81 9.5 4.8 55 3.6 0.1 4.0 4 0 0 4 4 4 0 Leucine rich repeat Orai-1 PF07856.12 KFO95781.1 - 3e-54 183.3 5.2 3.4e-54 183.2 5.2 1.0 1 0 0 1 1 1 1 Mediator of CRAC channel activity 7TM_GPCR_Str PF10326.9 KFO95781.1 - 0.033 13.5 5.0 0.9 8.8 0.5 2.0 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Str m04gp34like PF12216.8 KFO95781.1 - 0.041 13.5 0.4 0.51 9.9 0.1 2.0 1 1 1 2 2 2 0 Immune evasion protein Neurensin PF14927.6 KFO95781.1 - 1.5 8.5 4.5 4.3 7.1 0.3 2.4 1 1 2 3 3 3 0 Neurensin MORN PF02493.20 KFO95782.1 - 9.6e-29 97.6 41.4 6e-05 22.7 0.2 6.6 6 0 0 6 6 6 6 MORN repeat DUF3048_C PF17479.2 KFO95782.1 - 6.1 7.3 12.9 8 6.9 0.2 3.9 1 1 1 3 3 3 0 Protein of unknown function (DUF3048) C-terminal domain TMPIT PF07851.13 KFO95783.1 - 4.6e-150 499.3 17.6 5.2e-150 499.1 17.6 1.0 1 0 0 1 1 1 1 TMPIT-like protein N-SET PF11764.8 KFO95784.1 - 6.8e-29 101.2 0.0 6.8e-29 101.2 0.0 3.4 2 2 1 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.28 KFO95784.1 - 9.5e-17 61.9 2.0 9.5e-17 61.9 2.0 3.5 2 2 0 2 2 2 1 SET domain RRM_1 PF00076.22 KFO95784.1 - 7.1e-09 35.4 0.1 1.3e-08 34.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFO95784.1 - 0.016 14.8 0.7 0.13 11.9 0.2 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyoxalase PF00903.25 KFO95785.1 - 1.4e-21 77.0 0.5 1.2e-12 48.1 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KFO95785.1 - 1.1e-11 44.9 0.0 2e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KFO95785.1 - 0.002 18.3 0.0 0.86 9.7 0.0 2.9 3 1 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 KFO95785.1 - 0.0027 17.9 0.0 0.0068 16.6 0.0 1.6 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Nas2_N PF18265.1 KFO95786.1 - 1.5e-35 121.0 0.3 2.6e-35 120.2 0.3 1.4 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_2 PF13180.6 KFO95786.1 - 8.5e-10 38.8 0.0 1.5e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFO95786.1 - 5.4e-08 32.6 0.3 1.6e-07 31.0 0.1 1.9 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 KFO95786.1 - 1.5e-07 31.7 0.2 3.5e-07 30.5 0.1 1.7 2 0 0 2 2 2 1 PDZ domain GRASP55_65 PF04495.14 KFO95786.1 - 0.0035 17.7 0.0 0.0051 17.1 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain RdgC PF04381.12 KFO95786.1 - 0.059 12.6 0.1 0.083 12.1 0.1 1.1 1 0 0 1 1 1 0 Putative exonuclease, RdgC WD40 PF00400.32 KFO95787.1 - 3.3e-19 68.8 14.4 0.0033 18.2 0.0 9.0 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO95787.1 - 4.6e-05 23.6 0.1 0.013 15.8 0.0 4.6 4 1 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFO95787.1 - 0.00035 20.5 0.9 0.045 13.6 0.0 3.8 4 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A UPF0154 PF03672.13 KFO95787.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) RAB3GAP2_N PF14655.6 KFO95787.1 - 0.12 11.6 0.0 1.3 8.2 0.0 2.3 2 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus BCL_N PF04714.13 KFO95788.1 - 1.8e-10 40.7 1.7 4.4e-10 39.5 1.7 1.7 1 0 0 1 1 1 1 BCL7, N-terminal conserver region HLH PF00010.26 KFO95789.1 - 7.6e-07 29.0 1.0 7.6e-07 29.0 1.0 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain ZapB PF06005.12 KFO95789.1 - 0.00051 20.4 1.4 0.0014 19.0 1.4 1.7 1 0 0 1 1 1 1 Cell division protein ZapB HMMR_C PF15908.5 KFO95789.1 - 0.0066 16.7 0.2 0.015 15.6 0.2 1.5 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor C-terminal MSA-2c PF12238.8 KFO95789.1 - 0.0093 16.0 8.6 0.0093 16.0 8.6 3.1 3 0 0 3 3 3 1 Merozoite surface antigen 2c DivIC PF04977.15 KFO95789.1 - 0.033 13.9 2.1 0.064 13.0 2.1 1.4 1 0 0 1 1 1 0 Septum formation initiator Troponin PF00992.20 KFO95789.1 - 0.044 14.1 0.9 0.084 13.2 0.9 1.4 1 0 0 1 1 1 0 Troponin Cor1 PF04803.12 KFO95789.1 - 0.046 13.9 1.7 0.088 13.0 1.7 1.4 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region PHM7_cyt PF14703.6 KFO95789.1 - 0.061 13.5 0.3 0.14 12.4 0.3 1.6 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter TolA_bind_tri PF16331.5 KFO95789.1 - 0.066 13.3 2.6 0.14 12.2 2.6 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation Prominin PF05478.11 KFO95789.1 - 0.094 10.7 2.2 0.13 10.2 2.2 1.1 1 0 0 1 1 1 0 Prominin LRR_9 PF14580.6 KFO95790.1 - 9.5e-11 41.5 1.7 1.6e-07 31.0 0.1 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KFO95790.1 - 2.3e-10 40.1 9.2 0.0018 18.0 0.0 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFO95790.1 - 1.4e-07 31.7 15.8 0.057 13.9 0.0 4.1 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFO95790.1 - 0.071 13.2 6.0 0.97 9.7 0.3 4.6 5 0 0 5 5 5 0 Leucine Rich repeat FNIP PF05725.12 KFO95790.1 - 0.097 12.9 0.3 0.28 11.4 0.1 2.1 2 0 0 2 2 2 0 FNIP Repeat LRR_1 PF00560.33 KFO95790.1 - 1.1 10.0 14.6 5.2 8.0 0.9 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat Smac_DIABLO PF09057.10 KFO95791.1 - 3e-92 308.1 1.7 3.6e-92 307.8 1.7 1.0 1 0 0 1 1 1 1 Second Mitochondria-derived Activator of Caspases Sec1 PF00995.23 KFO95792.1 - 1.4e-123 414.1 0.0 1.6e-123 414.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF1629 PF07791.11 KFO95792.1 - 0.048 13.8 0.0 0.099 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1629) Phage_HK97_TLTM PF06120.11 KFO95792.1 - 0.14 11.3 0.2 0.22 10.6 0.2 1.2 1 0 0 1 1 1 0 Tail length tape measure protein CAP_GLY PF01302.25 KFO95793.1 - 8.6e-48 160.2 3.4 2.7e-24 85.0 0.5 2.3 2 0 0 2 2 2 2 CAP-Gly domain CLIP1_ZNF PF16641.5 KFO95793.1 - 8.5e-15 54.2 21.0 8.3e-09 35.1 4.6 2.4 2 0 0 2 2 2 2 CLIP1 zinc knuckle Fungal_TACC PF12709.7 KFO95793.1 - 0.00046 20.6 7.2 0.00046 20.6 7.2 15.7 6 5 7 16 16 16 1 Fungal Transforming acidic coiled-coil (TACC) proteins HTH_11 PF08279.12 KFO95793.1 - 0.063 13.2 0.1 2.3 8.3 0.0 3.5 2 0 0 2 2 2 0 HTH domain zf-CCHC_4 PF14392.6 KFO95793.1 - 1.4 8.7 6.6 2.6 7.8 0.3 2.5 2 0 0 2 2 2 0 Zinc knuckle HycI PF01750.18 KFO95793.1 - 2.2 8.1 11.5 0.97 9.3 1.0 4.1 3 0 0 3 3 3 0 Hydrogenase maturation protease PSP PF04046.16 KFO95794.1 - 5.6e-17 61.3 0.2 1.3e-16 60.1 0.2 1.7 1 0 0 1 1 1 1 PSP zf-CCHC PF00098.23 KFO95794.1 - 2.8e-05 24.0 4.0 5e-05 23.2 4.0 1.5 1 0 0 1 1 1 1 Zinc knuckle SMAP PF15477.6 KFO95795.1 - 2e-17 63.9 1.6 2e-17 63.9 1.6 4.1 3 2 0 3 3 3 1 Small acidic protein family Pap_E4 PF02711.14 KFO95795.1 - 0.33 11.9 0.2 0.33 11.9 0.2 5.5 2 1 1 3 3 3 0 E4 protein Rod_C PF10493.9 KFO95796.1 - 1.4e-257 855.5 9.5 1.4e-257 855.5 9.5 2.8 3 0 0 3 3 3 1 Rough deal protein C-terminal region MRP-S22 PF10245.9 KFO95796.1 - 0.015 15.1 0.1 0.037 13.8 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S22 APG12 PF04110.13 KFO95796.1 - 0.23 11.9 3.7 34 4.9 0.0 4.8 6 0 0 6 6 6 0 Ubiquitin-like autophagy protein Apg12 Metallophos_2 PF12850.7 KFO95797.1 - 4.9e-22 78.9 0.1 5.7e-22 78.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KFO95797.1 - 3.2e-05 24.5 1.3 0.12 12.8 0.1 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase SpoIIE PF07228.12 KFO95798.1 - 5.3e-15 55.9 0.0 7.8e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KFO95798.1 - 3.8e-06 26.7 0.7 3.5e-05 23.6 0.7 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KFO95798.1 - 6.3e-05 22.7 0.2 0.0084 15.8 0.1 2.3 2 1 0 2 2 2 2 Protein phosphatase 2C DUF1619 PF07773.11 KFO95799.1 - 9.7e-81 272.1 3.4 2e-77 261.3 2.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1619) VGPC1_C PF16799.5 KFO95800.1 - 1.4e-25 89.0 10.1 2.3e-25 88.3 10.1 1.4 1 0 0 1 1 1 1 C-terminal membrane-localisation domain of ion-channel, VCN1 Ion_trans PF00520.31 KFO95800.1 - 7.5e-07 28.6 6.6 1.1e-06 28.1 6.6 1.2 1 0 0 1 1 1 1 Ion transport protein TMF_DNA_bd PF12329.8 KFO95800.1 - 0.041 13.9 4.9 0.065 13.2 4.9 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding PLDc_2 PF13091.6 KFO95800.1 - 0.073 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 PLD-like domain CcdA PF07362.12 KFO95800.1 - 4.1 7.9 5.6 0.22 12.0 0.5 1.5 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA Metallophos PF00149.28 KFO95801.1 - 4.7e-41 141.5 0.1 5.9e-41 141.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFO95801.1 - 3.9e-18 65.6 1.7 7.7e-18 64.7 1.1 1.8 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain EF-hand_1 PF00036.32 KFO95802.1 - 1.2e-13 49.5 1.6 5.1e-06 25.7 0.9 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFO95802.1 - 1.4e-09 37.1 1.3 2e-06 27.2 0.8 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 KFO95802.1 - 2.4e-08 34.3 0.4 4.2e-05 23.9 0.1 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFO95802.1 - 4.8e-08 32.7 3.4 0.0024 17.7 0.1 4.0 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KFO95802.1 - 0.0017 17.7 1.0 0.0017 17.7 1.0 2.5 2 0 0 2 2 2 1 EF hand Caleosin PF05042.13 KFO95802.1 - 0.048 13.6 0.4 8.6 6.3 0.1 2.3 2 0 0 2 2 2 0 Caleosin related protein UPF0154 PF03672.13 KFO95802.1 - 0.1 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) PH PF00169.29 KFO95803.1 - 2.3e-20 73.1 0.0 3.4e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFO95803.1 - 4.2e-06 26.9 0.0 9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFO95803.1 - 0.00079 19.8 0.8 0.059 13.8 0.8 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 KFO95803.1 - 0.009 16.3 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 KFO95803.1 - 0.048 13.5 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain PH_4 PF15404.6 KFO95803.1 - 0.096 12.5 0.1 1.6 8.4 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain SM-ATX PF14438.6 KFO95804.1 - 3.8e-21 75.0 0.1 8.1e-21 74.0 0.1 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain LsmAD PF06741.13 KFO95804.1 - 1.2e-15 57.8 4.9 3e-15 56.5 4.9 1.8 1 0 0 1 1 1 1 LsmAD domain PAM2 PF07145.15 KFO95804.1 - 9.7e-07 28.1 1.0 3.5e-06 26.3 1.0 2.1 1 0 0 1 1 1 1 Ataxin-2 C-terminal region LSM PF01423.22 KFO95804.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 LSM domain BRAP2 PF07576.12 KFO95805.1 - 3e-36 123.6 1.1 6.4e-36 122.6 1.1 1.6 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KFO95805.1 - 1e-20 73.8 7.1 1e-20 73.8 7.1 2.3 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KFO95805.1 - 1.5e-08 34.8 7.0 1.5e-08 34.8 7.0 2.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFO95805.1 - 9.1e-08 31.8 6.1 9.1e-08 31.8 6.1 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFO95805.1 - 8.1e-06 26.0 4.7 8.1e-06 26.0 4.7 2.6 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KFO95805.1 - 1.1e-05 25.1 1.8 1.1e-05 25.1 1.8 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KFO95805.1 - 2.5e-05 24.1 5.7 2.5e-05 24.1 5.7 2.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFO95805.1 - 3.1e-05 23.9 0.3 3.1e-05 23.9 0.3 2.9 1 1 1 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFO95805.1 - 7.2e-05 22.6 6.2 7.2e-05 22.6 6.2 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KFO95805.1 - 0.0017 18.1 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-ANAPC11 PF12861.7 KFO95805.1 - 0.0042 17.1 3.1 0.02 15.0 3.1 2.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KFO95805.1 - 0.0056 16.5 18.3 0.03 14.2 7.7 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) KASH_CCD PF14662.6 KFO95805.1 - 0.0059 16.5 26.2 0.011 15.6 26.2 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-C3H2C3 PF17122.5 KFO95805.1 - 0.034 14.2 4.2 0.17 11.9 4.2 2.4 1 0 0 1 1 1 0 Zinc-finger FXMRP1_C_core PF12235.8 KFO95805.1 - 0.069 13.8 5.3 0.087 13.5 0.6 2.5 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal GBP_C PF02841.14 KFO95805.1 - 0.12 11.7 24.0 0.13 11.7 18.6 2.2 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain Zn_ribbon_17 PF17120.5 KFO95805.1 - 0.13 11.9 15.0 0.21 11.3 5.6 2.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Baculo_PEP_C PF04513.12 KFO95805.1 - 0.22 11.6 9.5 0.11 12.5 5.8 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vac_Fusion PF02346.16 KFO95805.1 - 0.23 11.1 3.5 0.91 9.2 0.8 2.8 1 1 1 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 DUF2935 PF11155.8 KFO95805.1 - 0.24 11.8 4.3 0.35 11.2 3.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) FapA PF03961.13 KFO95805.1 - 0.24 10.0 14.9 0.36 9.4 14.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Peptidase_S46 PF10459.9 KFO95805.1 - 0.37 9.4 8.9 0.57 8.8 8.9 1.2 1 0 0 1 1 1 0 Peptidase S46 FUSC PF04632.12 KFO95805.1 - 0.49 8.9 1.0 0.73 8.3 1.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Prok-RING_4 PF14447.6 KFO95805.1 - 0.74 9.7 18.1 0.24 11.3 7.4 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 UPF0242 PF06785.11 KFO95805.1 - 0.93 9.6 24.2 2 8.5 24.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NPV_P10 PF05531.12 KFO95805.1 - 1.2 9.7 8.4 9.1 6.8 6.0 3.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.19 KFO95805.1 - 1.7 6.4 18.7 0.99 7.2 13.8 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 KFO95805.1 - 2.2 7.3 21.0 0.52 9.3 17.7 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 KFO95805.1 - 2.8 7.4 11.5 5.3 6.5 11.5 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 KFO95805.1 - 2.9 7.1 12.7 5.8 6.1 12.7 1.5 1 0 0 1 1 1 0 TMPIT-like protein KELK PF15796.5 KFO95805.1 - 3.1 8.3 21.2 1.9 9.0 6.3 3.1 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase CREPT PF16566.5 KFO95805.1 - 3.7 7.7 20.2 1.5 9.0 12.1 3.1 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour zf-UBP_var PF17807.1 KFO95805.1 - 9.1 6.1 8.6 0.57 10.0 1.7 2.5 3 0 0 3 3 2 0 Variant UBP zinc finger DUF4407 PF14362.6 KFO95805.1 - 9.5 5.5 18.4 0.81 9.0 13.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) APH PF01636.23 KFO95806.1 - 4.1e-40 138.2 0.1 6.3e-40 137.6 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family HAD_2 PF13419.6 KFO95806.1 - 0.00013 22.1 0.0 0.00035 20.7 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Kdo PF06293.14 KFO95806.1 - 0.00032 20.1 0.0 0.00062 19.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Hydrolase PF00702.26 KFO95806.1 - 0.0022 18.3 0.0 0.0037 17.6 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase RIO1 PF01163.22 KFO95806.1 - 0.0034 17.0 0.0 0.19 11.3 0.0 2.3 2 0 0 2 2 2 1 RIO1 family EcKinase PF02958.20 KFO95806.1 - 0.0098 15.2 0.1 0.015 14.6 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF885 PF05960.11 KFO95806.1 - 0.048 13.3 0.0 0.074 12.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Pkinase PF00069.25 KFO95807.1 - 1.5e-61 208.1 0.0 3.1e-61 207.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO95807.1 - 1.2e-21 77.2 0.1 6.8e-21 74.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KFO95807.1 - 6.1e-05 22.5 0.2 0.00011 21.6 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFO95807.1 - 6.8e-05 22.3 0.0 0.00014 21.3 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 KFO95807.1 - 0.068 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase GPR_Gpa2_C PF11970.8 KFO95808.1 - 0.0038 17.3 1.2 0.011 15.8 1.2 1.8 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term ERp29_N PF07912.13 KFO95809.1 - 6.2e-44 149.2 0.3 9.5e-44 148.6 0.3 1.3 1 0 0 1 1 1 1 ERp29, N-terminal domain ERp29 PF07749.12 KFO95809.1 - 1.9e-17 63.9 4.1 3.2e-17 63.2 4.1 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain PRTase_1 PF11202.8 KFO95809.1 - 0.0077 15.5 0.8 0.013 14.8 0.8 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase (PRTase) NatB_MDM20 PF09797.9 KFO95810.1 - 4.2e-124 414.4 0.1 4.2e-124 414.4 0.1 2.1 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.6 KFO95810.1 - 0.0002 21.9 5.9 9.2 7.4 0.0 5.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFO95810.1 - 0.0029 18.1 7.3 0.77 10.3 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.17 KFO95810.1 - 0.063 13.7 2.1 0.78 10.2 0.2 3.2 3 1 1 4 4 4 0 Bacterial transcriptional activator domain TPR_17 PF13431.6 KFO95810.1 - 0.27 11.7 1.4 1.5e+02 3.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO95810.1 - 0.35 11.1 13.9 4.1 7.7 0.8 4.1 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KFO95810.1 - 0.41 10.9 8.2 12 6.3 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3510 PF12022.8 KFO95810.1 - 1.9 8.9 6.2 14 6.1 0.2 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3510) HECT PF00632.25 KFO95811.1 - 2e-40 139.2 0.0 4.1e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ribosomal_L6e PF01159.19 KFO95812.1 - 1.1e-42 145.0 1.2 1.1e-42 145.0 1.2 2.6 3 0 0 3 3 3 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 KFO95812.1 - 9.6e-28 96.2 11.5 9.6e-28 96.2 11.5 2.7 3 0 0 3 3 3 1 Ribosomal protein L6, N-terminal domain SH2 PF00017.24 KFO95813.1 - 2.9e-25 88.2 0.0 3.6e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 SH2 domain Y_phosphatase PF00102.27 KFO95814.1 - 6.6e-79 264.8 0.5 8.3e-79 264.5 0.5 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFO95814.1 - 7.7e-06 25.8 0.1 3.4e-05 23.6 0.1 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFO95814.1 - 0.00046 20.3 0.5 0.002 18.2 0.0 2.1 2 1 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KFO95814.1 - 0.0005 20.1 0.1 0.0017 18.4 0.0 2.0 1 1 1 2 2 2 1 Tyrosine phosphatase family Tab2_like PF06485.11 KFO95814.1 - 0.074 12.5 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 RNA-binding protein Tab2/Atab2 WSC PF01822.19 KFO95815.1 - 2.5e-33 114.1 15.8 3e-19 69.0 6.4 2.3 2 0 0 2 2 2 2 WSC domain Sulfotransfer_1 PF00685.27 KFO95815.1 - 7.7e-05 22.3 0.0 0.00021 20.8 0.0 1.6 1 1 1 2 2 2 1 Sulfotransferase domain 7tm_1 PF00001.21 KFO95816.1 - 1.2e-45 155.9 22.4 1.6e-45 155.5 22.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFO95816.1 - 0.31 10.6 26.7 0.043 13.4 21.4 2.1 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Fic PF02661.18 KFO95817.1 - 2.3e-27 95.7 0.0 4.8e-27 94.7 0.0 1.6 1 0 0 1 1 1 1 Fic/DOC family TPR_2 PF07719.17 KFO95817.1 - 0.0011 18.9 0.9 0.016 15.3 0.4 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFO95817.1 - 0.044 14.4 0.1 0.1 13.3 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat VMA21 PF09446.10 KFO95817.1 - 0.12 12.6 0.1 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 VMA21-like domain TPR_11 PF13414.6 KFO95817.1 - 0.5 10.1 4.9 1 9.1 0.0 2.9 3 1 1 4 4 4 0 TPR repeat RRM_1 PF00076.22 KFO95818.1 - 3.2e-33 113.4 0.1 1.2e-16 60.2 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LSM_int_assoc PF16605.5 KFO95818.1 - 3.7e-28 97.4 6.8 1.2e-27 95.7 6.8 2.0 1 0 0 1 1 1 1 LSM-interacting associated unstructured Lsm_interact PF05391.11 KFO95818.1 - 4.7e-07 29.1 2.4 1.1e-06 27.9 2.4 1.7 1 0 0 1 1 1 1 Lsm interaction motif RRM_occluded PF16842.5 KFO95818.1 - 1.5e-05 24.8 0.0 0.00018 21.3 0.0 2.3 2 0 0 2 2 2 1 Occluded RNA-recognition motif FAT PF02259.23 KFO95818.1 - 0.0029 16.9 5.2 0.0074 15.5 5.2 1.7 1 0 0 1 1 1 1 FAT domain PPP4R2 PF09184.11 KFO95818.1 - 0.0042 16.7 7.0 0.0093 15.6 7.0 1.5 1 0 0 1 1 1 1 PPP4R2 TPR_14 PF13428.6 KFO95818.1 - 0.011 16.4 16.2 16 6.6 0.4 7.3 6 2 3 9 9 8 0 Tetratricopeptide repeat Nup35_RRM_2 PF14605.6 KFO95818.1 - 0.019 15.0 0.1 6.5 6.8 0.0 2.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KFO95818.1 - 0.022 14.9 0.0 2.4 8.3 0.0 2.9 2 0 0 2 2 2 0 RNA recognition motif Spem1 PF15670.5 KFO95818.1 - 0.29 10.7 5.9 0.14 11.8 3.0 2.0 2 0 0 2 2 2 0 Spermatid maturation protein 1 V_ATPase_I PF01496.19 KFO95818.1 - 1 7.2 4.0 1.4 6.8 4.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CCDC71L PF15374.6 KFO95818.1 - 1.3 8.2 10.1 2.8 7.1 10.1 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L eIF3_subunit PF08597.10 KFO95818.1 - 1.6 8.6 23.5 5.6 6.8 23.5 1.8 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit RR_TM4-6 PF06459.12 KFO95818.1 - 2.5 7.9 10.4 6.5 6.5 10.4 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CENP-H PF05837.12 KFO95818.1 - 2.7 8.4 15.8 7.7 7.0 11.4 2.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Presenilin PF01080.17 KFO95818.1 - 3.9 6.1 6.4 6.4 5.4 6.4 1.2 1 0 0 1 1 1 0 Presenilin NifU_N PF01592.16 KFO95819.1 - 2.3e-55 186.2 0.1 2.6e-55 186.1 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Jag_N PF14804.6 KFO95819.1 - 0.22 11.9 2.8 7.7 6.9 0.1 2.7 3 0 0 3 3 3 0 Jag N-terminus DUF1899 PF08953.11 KFO95820.1 - 8.8e-32 108.8 0.0 1.7e-31 107.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KFO95820.1 - 5.1e-22 77.5 0.1 9.6e-22 76.6 0.1 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KFO95820.1 - 8.5e-12 45.4 4.5 0.0027 18.5 0.3 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO95820.1 - 5e-07 29.9 0.3 0.022 15.0 0.0 2.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain FIN1 PF17300.2 KFO95820.1 - 0.028 13.9 1.4 0.041 13.4 1.4 1.2 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 eIF2A PF08662.11 KFO95820.1 - 0.053 13.4 0.0 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 KFO95820.1 - 0.12 11.3 0.1 0.19 10.6 0.1 1.3 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain DSPc PF00782.20 KFO95821.1 - 4.3e-36 123.6 0.0 9.6e-36 122.5 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DEK_C PF08766.11 KFO95821.1 - 2.1e-14 53.2 2.6 2.1e-14 53.2 2.6 2.2 2 0 0 2 2 2 1 DEK C terminal domain Y_phosphatase PF00102.27 KFO95821.1 - 0.0086 15.7 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DAO PF01266.24 KFO95822.1 - 4.2e-38 131.8 0.1 4.8e-38 131.7 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Glu_dehyd_C PF16912.5 KFO95822.1 - 0.17 11.4 0.0 2.2 7.7 0.0 2.0 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Sugar_tr PF00083.24 KFO95823.1 - 5.5e-37 127.7 26.1 8e-25 87.6 9.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFO95823.1 - 2.2e-36 125.5 36.4 4.7e-21 75.1 21.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFO95823.1 - 0.0057 15.3 0.9 0.0057 15.3 0.9 3.5 3 1 1 4 4 4 2 MFS/sugar transport protein UCH PF00443.29 KFO95824.1 - 3.9e-31 108.5 0.0 3.5e-30 105.4 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFO95824.1 - 3.6e-13 49.8 0.7 1.2e-12 48.1 0.7 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase 2OG-FeII_Oxy_2 PF13532.6 KFO95825.1 - 1.4e-29 103.6 0.0 1.8e-29 103.3 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UDG PF03167.19 KFO95826.1 - 3.1e-24 85.7 0.0 4.3e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Forkhead PF00250.18 KFO95827.1 - 4.6e-35 119.7 0.1 7.9e-35 119.0 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain Ribosomal_L30_N PF08079.12 KFO95827.1 - 0.094 13.0 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain Myosin_head PF00063.21 KFO95828.1 - 1.4e-224 747.3 0.2 1e-186 622.1 0.4 2.0 2 0 0 2 2 2 2 Myosin head (motor domain) Zeta_toxin PF06414.12 KFO95828.1 - 0.027 13.7 0.0 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 KFO95828.1 - 0.07 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Myosin_TH1 PF06017.13 KFO95829.1 - 3e-32 111.8 0.8 3.8e-32 111.5 0.8 1.1 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding BTB_2 PF02214.22 KFO95830.1 - 1.4e-19 70.2 0.0 2.3e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KFO95830.1 - 4.4e-05 23.7 0.0 9.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KFO95830.1 - 0.0013 18.8 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Cob_adeno_trans PF01923.18 KFO95831.1 - 1.8e-56 190.8 0.0 2.1e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase T2SSF PF00482.23 KFO95831.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Hormone_3 PF00159.18 KFO95831.1 - 0.21 11.7 0.7 0.44 10.7 0.7 1.5 1 0 0 1 1 1 0 Pancreatic hormone peptide GHMP_kinases_N PF00288.26 KFO95832.1 - 1.7e-19 69.8 0.8 4.7e-19 68.4 0.8 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KFO95832.1 - 4.1e-06 27.1 1.4 7.1e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 KFO95832.1 - 0.0059 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Ion_trans PF00520.31 KFO95833.1 - 1.9e-15 56.8 17.0 2.6e-15 56.3 17.0 1.2 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 KFO95833.1 - 2.8e-15 56.7 0.1 5.2e-06 27.0 0.0 3.5 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFO95833.1 - 2.2e-10 40.5 0.1 0.00059 20.2 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KFO95833.1 - 2.8e-10 39.5 0.1 0.0017 18.7 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KFO95833.1 - 2.6e-08 34.3 0.2 0.0054 17.3 0.0 4.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFO95833.1 - 1.3e-07 31.7 0.1 0.38 11.1 0.0 3.9 3 1 0 3 3 3 3 Ankyrin repeats (many copies) GLTP PF08718.11 KFO95834.1 - 2.1e-33 115.7 0.0 3.3e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) FliS PF02561.14 KFO95834.1 - 0.027 14.7 0.1 3 8.2 0.0 2.5 2 0 0 2 2 2 0 Flagellar protein FliS GN3L_Grn1 PF08701.11 KFO95834.1 - 0.03 14.4 0.2 0.069 13.3 0.2 1.6 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase TPH PF13868.6 KFO95835.1 - 3.2e-24 85.1 141.4 3.6e-24 84.9 141.4 1.0 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain GIT1_C PF12205.8 KFO95836.1 - 3.3e-46 156.2 4.4 3.3e-46 156.2 4.4 2.5 2 0 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term GIT_SHD PF08518.11 KFO95836.1 - 2.7e-27 94.1 1.6 7.8e-14 51.0 0.1 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT_CC PF16559.5 KFO95836.1 - 4.3e-27 93.8 7.8 6.5e-27 93.2 6.6 2.1 2 0 0 2 2 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor ArfGap PF01412.18 KFO95836.1 - 2.2e-24 85.8 0.3 7.3e-24 84.1 0.0 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Ank_2 PF12796.7 KFO95836.1 - 1.9e-09 38.0 0.0 6.7e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFO95836.1 - 1.8e-08 34.5 0.0 7.4e-08 32.5 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFO95836.1 - 2e-08 34.6 0.0 2.8e-05 24.6 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KFO95836.1 - 0.00051 20.4 0.3 0.009 16.4 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 KFO95836.1 - 0.009 16.5 0.0 0.35 11.6 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Sen15 PF09631.10 KFO95836.1 - 0.012 15.9 0.2 0.058 13.7 0.0 2.3 2 0 0 2 2 2 0 Sen15 protein TTRAP PF14203.6 KFO95836.1 - 0.12 12.4 0.0 0.94 9.5 0.0 2.5 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein DMPK_coil PF08826.10 KFO95836.1 - 0.13 12.3 1.9 0.43 10.7 1.0 2.4 2 0 0 2 2 2 0 DMPK coiled coil domain like T7SS_ESX_EspC PF10824.8 KFO95836.1 - 0.39 11.2 4.2 2 8.9 0.1 3.6 4 0 0 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm Shugoshin_N PF07558.11 KFO95836.1 - 0.45 10.4 6.3 1.2 9.0 6.3 1.8 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region CRIC_ras_sig PF10534.9 KFO95836.1 - 0.66 10.2 8.0 0.35 11.1 0.2 4.2 5 0 0 5 5 5 0 Connector enhancer of kinase suppressor of ras GPCR_chapero_1 PF11904.8 KFO95837.1 - 6.9e-98 327.9 0.2 1e-97 327.3 0.2 1.3 1 0 0 1 1 1 1 GPCR-chaperone Ank_4 PF13637.6 KFO95837.1 - 9.4e-12 45.2 0.0 2.7e-11 43.8 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFO95837.1 - 5.5e-11 42.9 0.0 1.3e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFO95837.1 - 8.8e-10 38.0 0.0 0.002 18.4 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KFO95837.1 - 2.8e-09 37.0 0.0 1.7e-06 28.2 0.0 3.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KFO95837.1 - 8.9e-08 32.3 0.0 0.0058 17.0 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat UIM PF02809.20 KFO95837.1 - 0.04 13.8 18.6 0.28 11.2 1.6 4.4 4 0 0 4 4 4 0 Ubiquitin interaction motif YscJ_FliF PF01514.17 KFO95837.1 - 0.058 13.0 0.7 0.12 12.1 0.1 1.7 2 0 0 2 2 2 0 Secretory protein of YscJ/FliF family DUF1968 PF09291.10 KFO95837.1 - 0.1 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1968) RNA_pol_Rbc25 PF08292.12 KFO95837.1 - 0.11 12.8 0.1 0.11 12.8 0.1 1.9 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 SNF PF00209.18 KFO95838.1 - 2.5e-142 475.2 19.1 2.8e-142 475.1 19.1 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family RUN PF02759.19 KFO95839.1 - 1.7e-37 128.4 0.2 5.1e-37 126.9 0.1 1.9 2 0 0 2 2 2 1 RUN domain RabGAP-TBC PF00566.18 KFO95839.1 - 1.4e-34 119.7 6.6 8.4e-33 113.8 3.5 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PH_RBD PF12068.8 KFO95839.1 - 1.3e-33 115.9 0.0 3e-32 111.4 0.0 2.7 1 1 0 1 1 1 1 Rab-binding domain (RBD) Crystall PF00030.19 KFO95840.1 - 3.6e-57 190.5 0.2 2.3e-28 98.2 0.0 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.13 KFO95840.1 - 4.3e-05 23.4 0.0 0.0024 17.8 0.0 2.5 2 1 0 2 2 2 1 Peptidase inhibitor family I36 IL4_i_Ig PF18258.1 KFO95840.1 - 0.0014 18.8 0.8 29 5.0 0.0 4.1 1 1 3 4 4 4 2 Interleukin-4 inducing immunoglobulin-binding domain Crystall PF00030.19 KFO95841.1 - 2.2e-40 136.7 0.3 1.7e-28 98.7 0.1 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin IL4_i_Ig PF18258.1 KFO95841.1 - 0.00032 20.8 0.1 1.7 8.9 0.0 2.9 2 1 1 3 3 3 2 Interleukin-4 inducing immunoglobulin-binding domain Inhibitor_I36 PF03995.13 KFO95841.1 - 0.03 14.2 0.0 5.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Peptidase inhibitor family I36 Syncollin PF15138.6 KFO95841.1 - 0.13 12.5 0.0 4.1 7.6 0.0 2.2 1 1 1 2 2 2 0 Syncollin Pkinase PF00069.25 KFO95842.1 - 7e-74 248.5 0.0 1.1e-72 244.6 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO95842.1 - 6.8e-29 100.9 0.0 1.1e-28 100.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 KFO95842.1 - 6.2e-20 71.6 4.9 1.2e-19 70.7 4.9 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain PH PF00169.29 KFO95842.1 - 8.2e-11 42.4 0.3 1.6e-10 41.4 0.3 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 KFO95842.1 - 0.0018 17.6 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFO95842.1 - 0.0074 15.1 0.0 0.016 14.0 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Myosin_head PF00063.21 KFO95843.1 - 1.6e-83 281.1 0.0 2.9e-83 280.3 0.0 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) Taxilin PF09728.9 KFO95843.1 - 8.9e-05 21.8 30.8 8.9e-05 21.8 30.8 5.2 2 2 3 5 5 5 1 Myosin-like coiled-coil protein HTH_Bact PF18768.1 KFO95843.1 - 0.0032 17.0 0.5 0.011 15.4 0.5 1.8 1 0 0 1 1 1 1 Helix-turn-helix bacterial domain ADIP PF11559.8 KFO95843.1 - 0.0056 16.8 15.0 0.0056 16.8 15.0 7.9 4 3 2 8 8 8 3 Afadin- and alpha -actinin-Binding IQ PF00612.27 KFO95843.1 - 0.0071 16.0 0.2 0.0071 16.0 0.2 2.7 2 0 0 2 2 2 1 IQ calmodulin-binding motif Myosin_tail_1 PF01576.19 KFO95843.1 - 9 3.9 116.4 0.002 16.1 42.5 4.2 3 2 1 4 4 4 0 Myosin tail Sushi PF00084.20 KFO95844.1 - 1e-38 131.7 18.6 8.6e-12 45.5 0.9 4.3 4 0 0 4 4 4 4 Sushi repeat (SCR repeat) CUB PF00431.20 KFO95844.1 - 3.5e-21 75.6 0.0 1.9e-19 70.0 0.0 2.6 2 1 0 2 2 2 1 CUB domain Amnionless PF14828.6 KFO95844.1 - 0.14 11.0 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Amnionless Asp_Arg_Hydrox PF05118.15 KFO95845.1 - 6.2e-45 152.8 0.0 8.3e-45 152.4 0.0 1.2 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase UQ_con PF00179.26 KFO95845.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme DUF1096 PF06493.11 KFO95846.1 - 5.3 7.6 13.1 0.25 11.8 2.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1096) SRR1 PF07985.12 KFO95847.1 - 0.074 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 SRR1 GCFC PF07842.12 KFO95848.1 - 1.5e-98 329.9 18.4 7.1e-98 327.6 15.9 2.2 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 KFO95848.1 - 1.2e-16 60.3 4.3 2.4e-16 59.4 4.3 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFO95848.1 - 0.00015 21.8 1.1 0.00048 20.2 1.1 1.9 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.8 KFO95848.1 - 0.00022 21.6 0.4 0.00022 21.6 0.4 2.2 3 0 0 3 3 3 1 Tuftelin interacting protein N terminal Sulfotransfer_3 PF13469.6 KFO95849.1 - 2.1e-55 188.4 0.0 4.5e-55 187.4 0.0 1.6 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KFO95849.1 - 6.6e-07 29.1 0.0 8.2e-06 25.5 0.0 2.4 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 KFO95849.1 - 0.12 12.2 0.0 0.31 10.8 0.0 1.7 1 1 0 1 1 1 0 Sulfotransferase domain Crystall PF00030.19 KFO95850.1 - 1.3e-58 195.2 4.3 3.2e-29 101.0 0.4 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.13 KFO95850.1 - 2.6e-07 30.5 0.0 0.023 14.6 0.1 2.4 2 0 0 2 2 2 2 Peptidase inhibitor family I36 Crystall_3 PF08964.10 KFO95850.1 - 1.4e-05 25.2 0.2 0.12 12.6 0.0 2.6 2 1 0 2 2 2 2 Beta/Gamma crystallin IL4_i_Ig PF18258.1 KFO95850.1 - 0.0012 19.0 1.5 16 5.8 0.0 4.2 2 2 2 4 4 4 2 Interleukin-4 inducing immunoglobulin-binding domain Crystall PF00030.19 KFO95851.1 - 3.7e-54 180.9 5.8 2e-27 95.2 1.1 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin IP_trans PF02121.18 KFO95852.1 - 1.5e-109 365.3 2.3 1.7e-109 365.2 2.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Pkinase PF00069.25 KFO95853.1 - 3.8e-75 252.7 0.0 5.1e-75 252.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO95853.1 - 2.2e-31 109.1 0.0 3e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KFO95853.1 - 8.9e-13 48.4 0.0 1.9e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KFO95853.1 - 4.5e-08 32.8 0.0 7.1e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFO95853.1 - 0.0093 14.8 0.7 0.015 14.1 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KFO95853.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KFO95853.1 - 0.071 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 KFO95853.1 - 0.22 11.4 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sugar_tr PF00083.24 KFO95854.1 - 2.2e-93 313.6 24.9 2.6e-93 313.3 24.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFO95854.1 - 1.6e-16 60.2 31.5 1.6e-16 60.2 31.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily C_GCAxxG_C_C PF09719.10 KFO95854.1 - 0.033 14.5 0.0 0.077 13.3 0.0 1.6 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) Romo1 PF10247.9 KFO95854.1 - 2.3 8.7 16.2 1.5 9.3 0.2 4.0 4 0 0 4 4 4 0 Reactive mitochondrial oxygen species modulator 1 CCDC117 PF15810.5 KFO95855.1 - 1.6e-59 200.3 1.1 2.2e-59 199.9 1.1 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 117 bZIP_2 PF07716.15 KFO95856.1 - 6.2e-11 42.2 16.3 6.2e-11 42.2 16.3 2.5 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KFO95856.1 - 3.4e-10 39.9 16.0 7.5e-10 38.8 16.0 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KFO95856.1 - 3.1e-06 27.6 13.2 3.1e-06 27.6 13.2 1.7 2 0 0 2 2 2 1 bZIP Maf transcription factor HOOK PF05622.12 KFO95856.1 - 0.0086 14.3 13.2 0.011 14.0 13.2 1.1 1 0 0 1 1 1 1 HOOK protein YabA PF06156.13 KFO95856.1 - 0.031 14.9 13.6 0.81 10.4 12.5 2.8 1 1 1 2 2 2 0 Initiation control protein YabA KASH_CCD PF14662.6 KFO95856.1 - 0.038 13.8 17.4 0.069 13.0 17.4 1.3 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Cadherin_2 PF08266.12 KFO95856.1 - 0.1 12.5 3.8 0.16 11.8 3.6 1.5 1 1 0 1 1 1 0 Cadherin-like Phage_HK97_TLTM PF06120.11 KFO95856.1 - 0.32 10.2 5.4 0.4 9.8 5.4 1.2 1 0 0 1 1 1 0 Tail length tape measure protein CASP_C PF08172.12 KFO95856.1 - 1.1 8.6 9.2 0.53 9.6 6.7 1.6 1 1 1 2 2 2 0 CASP C terminal ZNRF_3_ecto PF18212.1 KFO95857.1 - 5.1e-47 158.2 0.0 8.7e-47 157.4 0.0 1.4 1 0 0 1 1 1 1 ZNRF-3 Ectodomain zf-RING_2 PF13639.6 KFO95857.1 - 7.2e-12 45.5 8.7 7.2e-12 45.5 8.7 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KFO95857.1 - 1.7e-11 43.7 1.8 6.5e-11 41.8 1.8 2.2 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFO95857.1 - 6.2e-08 32.4 8.7 6.2e-08 32.4 8.7 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFO95857.1 - 9.8e-06 25.4 7.8 9.8e-06 25.4 7.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFO95857.1 - 8.6e-05 22.4 7.0 0.00038 20.3 7.0 2.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFO95857.1 - 9.2e-05 22.2 8.2 0.00039 20.2 8.2 2.1 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFO95857.1 - 0.00022 21.2 4.9 0.00079 19.4 4.9 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFO95857.1 - 0.00055 19.7 6.3 0.00055 19.7 6.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFO95857.1 - 0.00088 19.5 12.1 0.00088 19.5 12.1 2.9 3 1 0 3 3 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFO95857.1 - 0.02 14.9 2.6 0.088 12.9 2.6 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PA PF02225.22 KFO95857.1 - 0.053 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 PA domain FANCL_C PF11793.8 KFO95857.1 - 0.08 13.1 4.7 0.55 10.5 4.7 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain CUB PF00431.20 KFO95858.1 - 1e-19 70.9 0.0 2.2e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 CUB domain Kringle PF00051.18 KFO95858.1 - 2.6e-19 69.3 7.2 6.4e-19 68.0 7.2 1.7 1 0 0 1 1 1 1 Kringle domain WSC PF01822.19 KFO95858.1 - 2.4e-17 62.9 9.4 2.4e-17 62.9 9.4 1.8 2 0 0 2 2 2 1 WSC domain AMOP PF03782.17 KFO95859.1 - 9e-51 171.8 7.3 2e-50 170.6 7.3 1.6 1 0 0 1 1 1 1 AMOP domain VWD PF00094.25 KFO95859.1 - 7.1e-16 58.9 0.2 2.1e-15 57.4 0.1 1.9 2 0 0 2 2 2 1 von Willebrand factor type D domain Sushi PF00084.20 KFO95859.1 - 5e-07 30.2 0.6 1.7e-06 28.5 0.6 2.0 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) Somatomedin_B PF01033.17 KFO95859.1 - 1.5e-06 28.5 13.8 1.5e-06 28.5 13.8 2.4 2 0 0 2 2 2 1 Somatomedin B domain PUF PF00806.19 KFO95860.1 - 2.5e-73 237.8 8.7 1.1e-09 37.5 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 KFO95860.1 - 0.022 15.1 1.1 5.7 7.3 0.1 3.9 1 1 3 4 4 4 0 CPL (NUC119) domain sCache_2 PF17200.4 KFO95860.1 - 0.032 14.1 0.1 52 3.6 0.0 4.1 4 0 0 4 4 4 0 Single Cache domain 2 Mt_ATP-synt_B PF05405.14 KFO95860.1 - 1.4 8.5 4.4 9.9 5.8 0.3 3.2 2 1 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Syndecan PF01034.20 KFO95861.1 - 2.5e-27 94.6 0.0 3.8e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.18 KFO95861.1 - 0.08 13.2 1.7 0.17 12.1 0.0 2.3 3 1 0 3 3 3 0 Glycophorin A TssR PF17643.1 KFO95861.1 - 0.27 9.1 0.1 0.34 8.8 0.1 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssR Mtp PF03821.16 KFO95862.1 - 2.8e-23 82.7 14.2 6.4e-16 58.7 4.9 2.1 1 1 1 2 2 2 2 Golgi 4-transmembrane spanning transporter DUF4728 PF15860.5 KFO95862.1 - 0.00021 21.9 4.1 0.00021 21.9 4.1 2.6 2 1 1 3 3 3 2 Domain of unknown function (DUF4728) MG3 PF17791.1 KFO95862.1 - 0.041 14.2 1.6 1.7 9.0 0.2 2.4 2 0 0 2 2 2 0 Macroglobulin domain MG3 VWA PF00092.28 KFO95863.1 - 3.8e-47 160.8 0.3 4.8e-47 160.4 0.3 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain FXa_inhibition PF14670.6 KFO95863.1 - 2.5e-21 75.6 49.9 1.6e-07 31.4 9.7 3.7 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site VWA_2 PF13519.6 KFO95863.1 - 1e-19 71.2 0.1 1.6e-19 70.5 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain EGF_CA PF07645.15 KFO95863.1 - 2.3e-16 59.7 39.5 5.4e-06 26.5 5.9 3.8 4 0 0 4 4 4 3 Calcium-binding EGF domain cEGF PF12662.7 KFO95863.1 - 1.2e-14 53.9 25.9 2.6e-05 24.0 2.8 3.9 3 0 0 3 3 3 3 Complement Clr-like EGF-like Matrilin_ccoil PF10393.9 KFO95863.1 - 1.5e-07 31.1 0.1 4.7e-07 29.6 0.1 1.9 1 0 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin EGF PF00008.27 KFO95863.1 - 0.038 14.3 5.1 0.038 14.3 5.1 4.3 4 1 1 5 5 4 0 EGF-like domain Sec23_trunk PF04811.15 KFO95863.1 - 0.05 13.2 0.3 0.35 10.4 0.1 2.2 2 0 0 2 2 2 0 Sec23/Sec24 trunk domain Plasmod_Pvs28 PF06247.11 KFO95863.1 - 0.98 9.8 35.5 1.3 9.4 3.6 4.1 4 0 0 4 4 4 0 Pvs28 EGF domain zf-NF-X1 PF01422.17 KFO95863.1 - 5.9 7.1 20.4 7.7 6.7 0.9 4.2 4 0 0 4 4 4 0 NF-X1 type zinc finger EGF_3 PF12947.7 KFO95863.1 - 9.2 6.6 39.8 1.3 9.3 3.7 4.5 5 0 0 5 5 5 0 EGF domain ANAPC4_WD40 PF12894.7 KFO95864.1 - 4.8e-15 55.6 11.9 5.7e-07 29.8 0.1 7.3 4 2 3 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFO95864.1 - 1.6e-06 28.7 8.0 0.68 10.9 0.0 6.3 7 0 0 7 7 7 2 WD domain, G-beta repeat RPN1_RPN2_N PF17781.1 KFO95864.1 - 6.1e-05 22.6 0.6 0.00015 21.3 0.6 1.6 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain Clathrin PF00637.20 KFO95864.1 - 6.1e-05 22.9 3.8 9.4e-05 22.3 1.7 2.4 1 1 1 2 2 2 1 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 KFO95864.1 - 7.4e-05 22.0 3.1 0.0043 16.1 0.0 3.8 4 0 0 4 4 4 1 Coatomer WD associated region A2L_zn_ribbon PF08792.10 KFO95864.1 - 0.0055 16.4 1.2 0.023 14.4 1.2 2.1 1 0 0 1 1 1 1 A2L zinc ribbon domain eIF2A PF08662.11 KFO95864.1 - 0.02 14.8 3.1 0.039 13.8 0.6 2.7 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Zona_pellucida PF00100.23 KFO95865.1 - 1.5e-30 106.9 0.8 2.9e-28 99.4 0.1 2.8 3 1 0 3 3 3 2 Zona pellucida-like domain zf-C2H2 PF00096.26 KFO95866.1 - 1.9e-13 50.1 25.4 0.00011 22.4 4.5 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO95866.1 - 9.3e-13 48.0 21.4 3e-06 27.4 0.8 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFO95866.1 - 8.9e-09 35.5 22.6 0.0066 17.2 2.6 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFO95866.1 - 1.2e-05 25.1 21.6 0.00011 22.0 1.8 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO95866.1 - 0.0011 19.2 14.2 0.15 12.4 1.3 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding C1_4 PF07975.12 KFO95866.1 - 0.0014 18.8 10.8 0.25 11.6 5.8 2.8 1 1 2 3 3 3 2 TFIIH C1-like domain Zn-ribbon_8 PF09723.10 KFO95866.1 - 0.002 18.2 8.3 0.015 15.4 1.7 2.4 2 0 0 2 2 2 2 Zinc ribbon domain XPA_N PF01286.18 KFO95866.1 - 0.0067 16.4 7.9 0.27 11.3 0.8 3.2 3 0 0 3 3 3 1 XPA protein N-terminal zf-AN1 PF01428.16 KFO95866.1 - 0.015 15.5 16.8 0.14 12.4 3.2 3.4 2 1 1 3 3 3 0 AN1-like Zinc finger GAGA PF09237.11 KFO95866.1 - 0.032 14.0 2.6 0.13 12.1 0.6 2.4 1 1 1 2 2 2 0 GAGA factor zf-met PF12874.7 KFO95866.1 - 0.11 12.9 0.4 0.11 12.9 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type CpXC PF14353.6 KFO95866.1 - 0.29 11.2 0.1 0.29 11.2 0.1 2.7 1 1 2 3 3 3 0 CpXC protein zf_UBZ PF18439.1 KFO95866.1 - 0.5 10.0 8.0 13 5.5 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF4379 PF14311.6 KFO95866.1 - 0.94 9.9 3.3 1.2 9.5 0.3 2.2 2 0 0 2 2 2 0 Probable Zinc-ribbon domain FYVE PF01363.21 KFO95866.1 - 1.9 8.7 13.9 1.1 9.5 6.7 2.3 1 1 1 2 2 2 0 FYVE zinc finger LIM PF00412.22 KFO95866.1 - 2.1 8.7 12.5 11 6.4 0.2 2.7 1 1 0 2 2 2 0 LIM domain zf-trcl PF13451.6 KFO95866.1 - 7.5 6.5 13.0 5.6 6.9 0.4 3.1 3 0 0 3 3 3 0 Probable zinc-ribbon domain 5-nucleotidase PF06189.12 KFO95867.1 - 3.3e-99 331.1 0.0 3.9e-99 330.9 0.0 1.0 1 0 0 1 1 1 1 5'-nucleotidase Acid_PPase PF12689.7 KFO95867.1 - 0.1 12.4 0.0 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 Acid Phosphatase adh_short PF00106.25 KFO95868.1 - 8.4e-18 64.5 0.0 7.8e-17 61.4 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFO95868.1 - 1.3e-12 47.8 0.0 5.5e-12 45.8 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ion_trans PF00520.31 KFO95869.1 - 1.3e-48 165.4 0.8 1.7e-48 165.0 0.8 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFO95869.1 - 1.4e-32 111.9 0.2 5.2e-32 110.1 0.2 2.0 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFO95869.1 - 9.5e-12 44.7 3.9 9.5e-12 44.7 3.9 1.9 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.5 KFO95869.1 - 0.013 15.6 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain DUF4064 PF13273.6 KFO95869.1 - 0.056 13.7 0.0 1.4 9.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Zona_pellucida PF00100.23 KFO95870.1 - 1.3e-38 133.3 2.9 5.4e-37 128.0 0.3 2.8 2 1 0 2 2 2 2 Zona pellucida-like domain HLH PF00010.26 KFO95871.1 - 1.3e-11 44.3 2.1 1.7e-11 43.9 1.4 1.5 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain XPG_I PF00867.18 KFO95872.1 - 2.6e-26 91.8 0.1 2.6e-26 91.8 0.1 2.1 3 0 0 3 3 3 1 XPG I-region Chromo_2 PF18704.1 KFO95872.1 - 4.6e-22 78.1 0.5 1.2e-21 76.7 0.5 1.8 1 0 0 1 1 1 1 Chromatin organization modifier domain 2 RecR PF02132.15 KFO95872.1 - 0.036 13.6 3.1 0.097 12.3 1.7 2.6 2 0 0 2 2 2 0 RecR protein SMC_N PF02463.19 KFO95873.1 - 3.1e-16 59.5 27.4 2.5e-15 56.5 27.4 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFO95873.1 - 3e-14 54.0 10.5 3e-14 54.0 10.5 5.4 2 2 1 4 4 4 1 AAA domain AAA_15 PF13175.6 KFO95873.1 - 8.9e-09 35.5 7.6 8.9e-09 35.5 7.6 3.3 2 1 1 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 KFO95873.1 - 1.6e-06 28.2 4.2 0.0054 16.6 0.3 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system WEMBL PF05701.11 KFO95873.1 - 0.00036 19.4 23.3 0.00036 19.4 23.3 4.1 2 2 1 3 3 3 2 Weak chloroplast movement under blue light AAA_29 PF13555.6 KFO95873.1 - 0.0063 16.2 0.2 0.012 15.3 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF1474 PF07342.11 KFO95873.1 - 0.026 15.1 0.6 0.026 15.1 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1474) Spc7 PF08317.11 KFO95873.1 - 2 7.2 89.0 0.49 9.2 12.5 5.1 2 2 2 4 4 4 0 Spc7 kinetochore protein EF-hand_7 PF13499.6 KFO95874.1 - 2.3e-25 88.8 4.5 2.7e-16 59.7 0.7 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KFO95874.1 - 5.6e-25 85.0 12.9 9.6e-08 31.1 0.1 4.6 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 KFO95874.1 - 9.9e-23 78.1 5.5 2.9e-07 29.9 0.1 4.7 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 KFO95874.1 - 2.3e-17 61.6 9.4 6.1e-06 25.5 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KFO95874.1 - 2.8e-13 49.5 11.5 3e-05 23.8 0.4 4.3 4 1 0 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFO95874.1 - 1.5e-05 25.3 2.0 0.061 13.6 0.5 3.3 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KFO95874.1 - 0.00025 21.2 0.1 0.069 13.4 0.0 2.8 3 0 0 3 3 3 1 Dockerin type I domain p25-alpha PF05517.12 KFO95874.1 - 0.0014 18.8 1.2 0.051 13.7 0.4 2.4 2 0 0 2 2 2 1 p25-alpha Caleosin PF05042.13 KFO95874.1 - 0.0023 17.9 6.2 0.1 12.5 3.3 3.3 2 1 0 2 2 2 1 Caleosin related protein EF-hand_9 PF14658.6 KFO95874.1 - 0.0034 17.7 0.1 5.6 7.4 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain IL3 PF02059.15 KFO95874.1 - 0.0041 17.2 0.1 0.016 15.2 0.0 1.9 2 0 0 2 2 2 1 Interleukin-3 EF-hand_4 PF12763.7 KFO95874.1 - 0.034 14.1 7.1 9.8 6.2 0.0 3.9 2 1 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand DUF1394 PF07159.12 KFO95876.1 - 9.1e-135 448.7 0.6 1e-134 448.6 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) DEAD PF00270.29 KFO95877.1 - 2.2e-77 258.8 0.0 3.6e-77 258.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFO95877.1 - 1.2e-27 96.5 0.1 5.5e-27 94.3 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SPRY PF00622.28 KFO95877.1 - 2.3e-23 82.6 1.0 3.6e-23 82.0 0.2 1.8 2 0 0 2 2 2 1 SPRY domain CMS1 PF14617.6 KFO95877.1 - 0.003 16.9 0.1 0.013 14.8 0.0 1.9 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 KFO95877.1 - 0.0056 16.7 0.0 0.18 11.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Nbas_N PF15492.6 KFO95878.1 - 1e-173 576.3 0.2 2.1e-173 575.2 0.2 1.6 1 0 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal Sec39 PF08314.11 KFO95878.1 - 8.8e-30 103.8 7.9 2e-17 63.0 1.1 2.5 1 1 1 2 2 2 2 Secretory pathway protein Sec39 ANAPC4_WD40 PF12894.7 KFO95878.1 - 0.011 16.0 0.0 4.6 7.6 0.0 3.4 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain GP67 PF17634.2 KFO95878.1 - 0.13 12.7 2.6 0.33 11.4 2.6 1.6 1 0 0 1 1 1 0 Gene product 67 LRAT PF04970.13 KFO95879.1 - 8e-10 39.1 0.1 8.3e-05 22.9 0.0 2.5 1 1 1 2 2 2 2 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 KFO95879.1 - 0.0059 16.6 0.0 0.021 14.9 0.0 1.9 1 1 0 1 1 1 1 NlpC/P60 family Pkinase PF00069.25 KFO95881.1 - 1.6e-35 122.8 0.0 2.2e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO95881.1 - 1.1e-18 67.5 0.0 1.5e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFO95881.1 - 1.4e-05 24.6 0.0 2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Lipase_GDSL_2 PF13472.6 KFO95882.1 - 0.00085 19.8 0.0 0.0031 18.0 0.0 1.9 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 KFO95882.1 - 0.0048 16.2 0.0 0.0089 15.3 0.0 1.3 1 0 0 1 1 1 1 OSK domain Tmemb_cc2 PF10267.9 KFO95882.1 - 0.065 12.4 0.5 0.094 11.8 0.5 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Lipase_GDSL PF00657.22 KFO95882.1 - 0.22 11.5 0.0 0.85 9.6 0.0 1.9 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase GREB1 PF15782.5 KFO95883.1 - 0 3446.7 20.0 0 3446.3 20.0 1.1 1 0 0 1 1 1 1 Gene regulated by oestrogen in breast cancer PSCyt3 PF07627.11 KFO95883.1 - 0.36 11.1 3.0 0.68 10.2 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1588) E7 PF00527.18 KFO95883.1 - 4.1 7.7 10.3 4.4 7.6 0.5 3.5 3 0 0 3 3 3 0 E7 protein, Early protein E2F_CC-MB PF16421.5 KFO95884.1 - 1.9e-30 105.1 0.6 3.3e-30 104.3 0.6 1.4 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 KFO95884.1 - 8.9e-25 86.6 0.4 2.2e-24 85.3 0.1 1.8 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 KFO95884.1 - 0.0028 17.5 0.0 0.0057 16.5 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF603 PF04645.12 KFO95884.1 - 0.043 13.5 0.5 9.4 5.9 0.2 2.3 1 1 0 2 2 2 0 Protein of unknown function, DUF603 HTH_17 PF12728.7 KFO95884.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_47 PF16221.5 KFO95884.1 - 0.16 11.6 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 winged helix-turn-helix E2F_CC-MB PF16421.5 KFO95885.1 - 2.8e-29 101.3 0.2 5.3e-29 100.4 0.2 1.5 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 KFO95885.1 - 4.9e-22 77.8 0.0 1.1e-21 76.7 0.0 1.6 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 KFO95885.1 - 0.024 14.5 0.0 0.056 13.3 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_47 PF16221.5 KFO95885.1 - 0.083 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 winged helix-turn-helix HTH_17 PF12728.7 KFO95885.1 - 0.12 12.5 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Pkinase PF00069.25 KFO95886.1 - 2.6e-61 207.3 0.0 2.6e-61 207.3 0.0 3.1 4 0 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO95886.1 - 1.4e-29 103.2 0.6 6.4e-29 101.0 0.0 2.6 2 0 0 2 2 2 1 Protein tyrosine kinase Rho_Binding PF08912.11 KFO95886.1 - 3.1e-25 88.8 12.9 3.1e-25 88.8 12.9 13.0 8 3 3 12 12 12 1 Rho Binding PH PF00169.29 KFO95886.1 - 3.2e-07 30.8 1.3 0.00013 22.5 0.1 3.0 2 0 0 2 2 2 2 PH domain C1_1 PF00130.22 KFO95886.1 - 0.0001 22.1 6.4 0.00021 21.1 6.4 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.16 KFO95886.1 - 0.00061 19.9 15.4 0.00061 19.9 15.4 11.0 8 3 4 12 12 12 1 Hr1 repeat APH PF01636.23 KFO95886.1 - 0.003 17.5 0.2 0.037 14.0 0.1 2.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_C PF00433.24 KFO95886.1 - 1.1 10.1 3.1 4.3 8.1 3.1 2.2 1 1 0 1 1 1 0 Protein kinase C terminal domain LLC1 PF14945.6 KFO95888.1 - 3.7e-06 27.5 4.8 8.1e-06 26.4 2.2 1.9 1 1 1 2 2 2 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Exonuc_V_gamma PF04257.14 KFO95888.1 - 0.021 13.1 1.6 0.023 12.9 1.6 1.0 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit Thioredoxin PF00085.20 KFO95889.1 - 3.1e-66 219.8 0.0 1e-31 109.0 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 KFO95889.1 - 1.2e-11 45.0 0.6 0.00045 20.7 0.0 3.6 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_6 PF13848.6 KFO95889.1 - 1.1e-07 31.9 0.0 0.15 12.0 0.0 3.3 3 0 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFO95889.1 - 1.8e-07 31.3 0.0 0.0038 17.4 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KFO95889.1 - 1.1e-06 28.9 0.0 0.11 12.8 0.0 3.7 2 2 2 4 4 4 2 Thioredoxin-like OST3_OST6 PF04756.13 KFO95889.1 - 3e-06 26.8 0.0 0.003 17.0 0.0 2.3 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 KFO95889.1 - 0.00013 21.9 0.0 0.26 11.4 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin domain AhpC-TSA PF00578.21 KFO95889.1 - 0.0012 18.7 0.0 1.8 8.5 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.6 KFO95889.1 - 0.02 14.7 0.0 0.45 10.3 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin HyaE PF07449.11 KFO95889.1 - 0.04 13.9 0.0 3.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.6 KFO95889.1 - 0.045 13.9 0.7 1.8 8.7 0.1 3.0 2 2 2 4 4 4 0 Thioredoxin DUF3228 PF11539.8 KFO95889.1 - 0.059 12.9 0.0 12 5.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3228) TraF PF13728.6 KFO95889.1 - 0.068 13.0 0.0 2 8.2 0.0 2.2 2 0 0 2 2 2 0 F plasmid transfer operon protein Calsequestrin PF01216.17 KFO95889.1 - 0.075 12.1 0.0 0.84 8.6 0.0 2.2 2 0 0 2 2 2 0 Calsequestrin V-ATPase_C PF03223.15 KFO95890.1 - 1.6e-160 534.5 1.3 1.8e-160 534.4 1.3 1.0 1 0 0 1 1 1 1 V-ATPase subunit C KxDL PF10241.9 KFO95890.1 - 0.038 14.3 1.3 0.71 10.2 0.1 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein NUC153 PF08159.12 KFO95891.1 - 1.5e-12 47.0 0.9 3.2e-12 46.0 0.9 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 KFO95891.1 - 0.03 15.2 0.0 8.2 7.5 0.0 3.2 4 0 0 4 4 4 0 WD domain, G-beta repeat Orn_Arg_deC_N PF02784.16 KFO95892.1 - 9e-93 310.2 0.0 1.2e-92 309.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KFO95892.1 - 2.8e-20 72.3 0.0 4e-20 71.9 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain EF-hand_7 PF13499.6 KFO95893.1 - 3.4e-28 97.9 3.5 2.7e-17 63.0 0.1 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KFO95893.1 - 5.7e-27 91.2 5.4 3.2e-07 29.4 0.3 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFO95893.1 - 2.2e-23 80.1 3.7 5.5e-07 29.0 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFO95893.1 - 1.2e-21 75.2 6.3 3.3e-07 29.5 0.3 4.5 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 KFO95893.1 - 8.5e-20 70.4 6.3 3.1e-08 33.4 0.1 3.7 3 2 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFO95893.1 - 4.4e-07 30.2 0.1 0.0071 16.6 0.0 3.3 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFO95893.1 - 4.8e-06 26.5 0.7 0.18 11.8 0.0 3.4 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 KFO95893.1 - 0.0025 17.6 0.4 4.1 7.3 0.1 3.0 3 0 0 3 3 3 2 EF hand Dockerin_1 PF00404.18 KFO95893.1 - 0.0032 17.6 0.0 1.4 9.1 0.0 2.5 2 1 0 2 2 2 2 Dockerin type I domain Ribonuc_red_sm PF00268.21 KFO95894.1 - 2.9e-121 404.2 3.7 3.4e-121 404.0 3.7 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain zf-C2H2 PF00096.26 KFO95895.1 - 2.3e-14 53.0 22.2 7.7e-05 22.9 0.7 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO95895.1 - 1.1e-11 44.6 9.6 4.4e-07 30.0 1.6 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFO95895.1 - 2.1e-07 31.2 20.6 0.0066 17.2 2.2 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFO95895.1 - 0.00032 21.3 8.4 0.61 10.8 0.2 3.9 2 1 2 4 4 4 2 FOXP coiled-coil domain zf_Hakai PF18408.1 KFO95895.1 - 0.015 14.9 0.3 0.015 14.9 0.3 2.5 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain zf-C2H2_6 PF13912.6 KFO95895.1 - 0.035 14.1 0.8 0.035 14.1 0.8 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 KFO95895.1 - 0.047 14.0 1.3 0.047 14.0 1.3 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KFO95895.1 - 0.36 11.3 7.2 12 6.4 0.2 3.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFO95895.1 - 5.6 7.4 13.5 27 5.2 1.7 3.7 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding CP2 PF04516.15 KFO95896.1 - 1.6e-80 269.7 3.3 2.6e-80 269.0 3.3 1.3 1 0 0 1 1 1 1 CP2 transcription factor zf-RRN7 PF11781.8 KFO95897.1 - 9.5e-11 41.2 4.3 3.5e-10 39.4 4.3 2.1 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF411 PF04214.13 KFO95897.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF 14-3-3 PF00244.20 KFO95898.1 - 4.1e-107 356.7 5.2 4.7e-107 356.6 5.2 1.0 1 0 0 1 1 1 1 14-3-3 protein FliM PF02154.15 KFO95898.1 - 0.095 12.6 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Flagellar motor switch protein FliM Peptidase_C98 PF15499.6 KFO95898.1 - 0.11 11.9 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase XhlA PF10779.9 KFO95898.1 - 3.1 8.1 4.8 0.8 10.0 1.0 1.9 2 0 0 2 2 2 0 Haemolysin XhlA Reprolysin_5 PF13688.6 KFO95899.1 - 2.8e-36 125.5 0.0 5.7e-36 124.5 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KFO95899.1 - 3.2e-32 112.0 0.1 7.1e-32 110.9 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM17_MPD PF16698.5 KFO95899.1 - 1.4e-22 79.8 17.1 1.4e-22 79.8 17.1 4.0 2 1 0 2 2 2 1 Membrane-proximal domain, switch, for ADAM17 Disintegrin PF00200.23 KFO95899.1 - 4.9e-14 52.9 25.2 4.9e-14 52.9 25.2 3.3 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 KFO95899.1 - 3.9e-13 50.0 0.2 8.1e-13 49.0 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 KFO95899.1 - 1.3e-10 41.5 0.4 1e-05 25.6 0.1 3.2 2 1 0 2 2 2 2 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 KFO95899.1 - 1.3e-07 32.0 0.1 3.4e-07 30.6 0.1 1.7 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_4 PF13583.6 KFO95899.1 - 1.8e-05 24.5 0.1 3.1e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Lipase_GDSL_2 PF13472.6 KFO95900.1 - 6.5e-23 82.0 0.0 1e-22 81.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFO95900.1 - 1.3e-18 67.7 0.0 1.5e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CP_ATPgrasp_2 PF14403.6 KFO95900.1 - 0.15 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 CPSF73-100_C PF11718.8 KFO95901.1 - 7.9e-55 185.7 0.4 1.4e-54 184.9 0.4 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KFO95901.1 - 2.7e-34 117.8 0.0 6.3e-34 116.6 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 KFO95901.1 - 8.8e-22 76.8 0.2 2e-21 75.7 0.2 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 KFO95901.1 - 6.7e-19 68.7 0.2 1.1e-18 68.0 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KFO95901.1 - 1.4e-18 67.1 0.0 3.3e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KFO95901.1 - 5e-08 32.7 0.3 4e-07 29.8 0.1 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KFO95901.1 - 3.3e-06 27.1 0.2 6.3e-05 22.9 0.1 3.0 2 1 1 3 3 3 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 KFO95901.1 - 0.0016 17.7 1.5 0.0017 17.6 0.1 1.8 2 0 0 2 2 2 1 Putative beta-lactamase-like family DUF1611 PF07755.11 KFO95901.1 - 0.022 14.0 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain ICAP-1_inte_bdg PF10480.9 KFO95902.1 - 5.2e-128 424.9 7.2 5.8e-128 424.8 7.2 1.0 1 0 0 1 1 1 1 Beta-1 integrin binding protein PID PF00640.23 KFO95902.1 - 1.1e-05 25.4 0.0 2.1e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) YCII PF03795.14 KFO95902.1 - 0.073 13.5 0.0 0.12 12.7 0.0 1.6 1 1 0 1 1 1 0 YCII-related domain DUF4015 PF13200.6 KFO95902.1 - 0.14 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain Herpes_UL6 PF01763.16 KFO95902.1 - 0.3 9.5 2.9 2.9 6.3 1.0 2.0 2 0 0 2 2 2 0 Herpesvirus UL6 like Glyco_hydro_31 PF01055.26 KFO95903.1 - 1.1e-87 295.1 1.1 1.2e-86 291.7 1.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Ras PF00071.22 KFO95904.1 - 4.2e-33 114.2 0.0 5.8e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO95904.1 - 3.5e-21 75.6 0.0 5.8e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO95904.1 - 1.6e-07 30.9 0.0 1.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFO95904.1 - 0.0051 16.2 0.0 0.007 15.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FtsZ_C PF12327.8 KFO95904.1 - 0.15 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 FtsZ family, C-terminal domain Prothymosin PF03247.14 KFO95905.1 - 0.35 11.3 16.1 0.052 14.0 11.1 2.0 2 0 0 2 2 2 0 Prothymosin/parathymosin family LAP1C PF05609.12 KFO95905.1 - 2.7 7.0 16.5 3 6.9 16.5 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC45 PF02724.14 KFO95905.1 - 4.4 5.5 16.0 5.1 5.3 16.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Mitoc_L55 PF09776.9 KFO95905.1 - 4.6 7.0 8.3 0.39 10.5 2.5 2.0 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L55 RVT_1 PF00078.27 KFO95906.1 - 0.00014 21.5 0.0 0.00026 20.6 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.11 KFO95906.1 - 0.26 11.0 0.6 0.43 10.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) RRM_7 PF16367.5 KFO95907.1 - 2.5e-38 130.1 0.0 2.2e-36 123.9 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif CEBP_ZZ PF16366.5 KFO95907.1 - 4.9e-21 74.7 5.2 1.2e-20 73.5 5.2 1.7 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 KFO95907.1 - 4e-12 45.8 0.0 7.8e-07 28.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-U1 PF06220.12 KFO95907.1 - 0.074 12.8 0.3 0.21 11.4 0.3 1.7 1 0 0 1 1 1 0 U1 zinc finger HSP20 PF00011.21 KFO95907.1 - 0.14 12.3 0.0 0.49 10.6 0.0 1.8 2 0 0 2 2 2 0 Hsp20/alpha crystallin family zf-B_box PF00643.24 KFO95907.1 - 0.39 10.9 5.9 0.91 9.7 5.9 1.5 1 0 0 1 1 1 0 B-box zinc finger C1q PF00386.21 KFO95908.1 - 9.6e-39 132.5 0.0 1.3e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFO95908.1 - 2.9e-16 59.0 57.6 1.9e-09 37.1 25.3 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) BclA_C PF18573.1 KFO95908.1 - 0.021 14.7 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 BclA C-terminal domain DUF5523 PF17661.1 KFO95909.1 - 1.5e-94 316.5 11.9 1.5e-94 316.5 11.9 2.4 2 0 0 2 2 2 1 Family of unknown function (DUF5523) CC2D2AN-C2 PF15625.6 KFO95909.1 - 6.8e-60 201.7 0.1 1.2e-59 200.9 0.1 1.4 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain C2 PF00168.30 KFO95909.1 - 3.3e-09 37.0 0.1 9.2e-05 22.7 0.0 2.9 2 1 0 2 2 2 2 C2 domain DUF3987 PF13148.6 KFO95909.1 - 0.17 10.9 15.4 0.025 13.6 8.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Endonuc_Holl PF10107.9 KFO95909.1 - 0.43 10.4 8.3 2.5 8.0 8.3 2.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Histone_HNS PF00816.21 KFO95909.1 - 1.8 9.4 8.0 10 7.0 6.0 3.2 2 0 0 2 2 2 0 H-NS histone family F-box-like PF12937.7 KFO95910.1 - 4.7e-15 55.2 0.1 1.4e-14 53.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KFO95910.1 - 4.9e-11 42.7 1.2 0.00013 22.3 0.0 3.5 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFO95910.1 - 5.3e-11 41.7 2.7 0.013 15.4 0.0 4.5 4 0 0 4 4 4 3 Leucine Rich repeat F-box PF00646.33 KFO95910.1 - 1.2e-10 40.9 0.1 9.5e-10 38.1 0.0 2.4 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 KFO95910.1 - 4.2e-06 26.6 2.0 1.5 9.7 0.0 5.5 4 1 0 4 4 4 2 Leucine Rich Repeat Hemerythrin PF01814.23 KFO95910.1 - 6.8e-06 26.7 5.2 0.00027 21.5 0.5 2.1 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain LRR_8 PF13855.6 KFO95910.1 - 0.00049 19.8 0.7 0.49 10.2 0.0 3.4 2 1 0 2 2 2 2 Leucine rich repeat F-box_4 PF15966.5 KFO95910.1 - 0.014 15.3 0.1 0.072 13.0 0.0 2.2 2 0 0 2 2 2 0 F-box PRANC PF09372.10 KFO95910.1 - 0.062 13.6 0.1 0.25 11.7 0.0 2.1 2 0 0 2 2 2 0 PRANC domain FTCD_C PF04961.12 KFO95910.1 - 0.4 10.4 2.6 1.9 8.2 1.5 2.3 1 1 0 2 2 2 0 Formiminotransferase-cyclodeaminase Rib_hydrolayse PF02267.17 KFO95911.1 - 7.3e-18 64.9 0.0 7.8e-18 64.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosyl cyclase Rib_hydrolayse PF02267.17 KFO95912.1 - 4.4e-98 327.5 0.3 5.1e-98 327.3 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosyl cyclase FGF-BP1 PF06473.12 KFO95913.1 - 1.1e-61 208.6 13.4 2e-61 207.7 13.4 1.4 1 1 0 1 1 1 1 FGF binding protein 1 (FGF-BP1) Terminase_4 PF05119.12 KFO95913.1 - 0.015 15.7 0.1 0.57 10.7 0.1 2.4 2 0 0 2 2 2 0 Phage terminase, small subunit FGF-BP1 PF06473.12 KFO95914.1 - 1.6e-49 168.8 0.3 1.9e-49 168.6 0.3 1.1 1 0 0 1 1 1 1 FGF binding protein 1 (FGF-BP1) Prominin PF05478.11 KFO95915.1 - 1.1e-256 853.9 13.0 1.2e-256 853.6 13.0 1.0 1 0 0 1 1 1 1 Prominin Tweety PF04906.13 KFO95915.1 - 0.0011 17.7 17.3 0.0031 16.2 0.4 3.2 2 1 0 3 3 3 2 Tweety ALIX_LYPXL_bnd PF13949.6 KFO95915.1 - 0.1 11.9 2.5 0.12 11.6 0.3 2.1 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV DUF1218 PF06749.12 KFO95915.1 - 0.13 12.8 13.5 1.6 9.3 2.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) Cyt_bd_oxida_II PF02322.15 KFO95915.1 - 0.28 10.5 5.7 4.6 6.5 0.1 2.2 2 0 0 2 2 2 0 Cytochrome bd terminal oxidase subunit II Noelin-1 PF12308.8 KFO95915.1 - 0.72 9.9 2.9 11 6.1 0.1 2.9 3 0 0 3 3 3 0 Neurogenesis glycoprotein DUF1664 PF07889.12 KFO95915.1 - 1.1 9.3 9.7 4.9 7.2 1.0 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Claudin_2 PF13903.6 KFO95915.1 - 1.6 8.5 10.0 4 7.1 3.2 2.7 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF747 PF05346.11 KFO95916.1 - 2.4e-102 342.7 21.3 5.1e-102 341.6 21.3 1.5 1 1 0 1 1 1 1 Eukaryotic membrane protein family DASH_Dad4 PF08650.10 KFO95916.1 - 0.069 13.1 3.6 0.26 11.3 2.2 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad4 LIM_bind PF01803.16 KFO95917.1 - 1.7e-55 188.2 10.6 4.5e-44 150.8 0.5 2.8 2 1 1 3 3 3 2 LIM-domain binding protein LID PF17916.1 KFO95917.1 - 1.7e-18 65.9 2.5 3.2e-18 65.1 2.5 1.5 1 0 0 1 1 1 1 LIM interaction domain (LID) DTHCT PF08070.11 KFO95917.1 - 0.016 16.0 2.5 0.051 14.3 2.5 1.8 1 0 0 1 1 1 0 DTHCT (NUC029) region zf-DNL PF05180.12 KFO95917.1 - 0.085 12.8 0.2 0.17 11.9 0.2 1.4 1 0 0 1 1 1 0 DNL zinc finger Coilin_N PF15862.5 KFO95917.1 - 0.12 12.2 2.6 0.23 11.2 2.6 1.5 1 0 0 1 1 1 0 Coilin N-terminus Vpu PF00558.19 KFO95917.1 - 0.52 10.1 1.6 6.8 6.5 0.0 2.8 3 0 0 3 3 3 0 Vpu protein adh_short_C2 PF13561.6 KFO95918.1 - 0.14 11.7 0.0 0.14 11.7 0.0 1.0 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase HTH_IclR PF09339.10 KFO95918.1 - 0.18 11.6 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain Peptidase_M17 PF00883.21 KFO95919.1 - 6.6e-112 373.8 0.1 3.5e-111 371.4 0.1 1.9 1 1 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 KFO95919.1 - 1.2e-18 67.2 0.0 2.3e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Med28 PF11594.8 KFO95920.1 - 1e-24 87.1 2.1 2.3e-18 66.5 1.0 2.1 1 1 1 2 2 2 2 Mediator complex subunit 28 Filament PF00038.21 KFO95920.1 - 0.00068 19.3 1.2 0.00069 19.3 1.2 1.1 1 0 0 1 1 1 1 Intermediate filament protein HTH_34 PF13601.6 KFO95920.1 - 0.0048 17.0 0.1 0.012 15.8 0.1 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain HSCB_C PF07743.13 KFO95920.1 - 0.074 13.5 3.3 0.37 11.3 1.3 2.2 1 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain Sec2p PF06428.11 KFO95920.1 - 0.097 12.6 3.9 0.15 12.0 3.9 1.3 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p cwf21 PF08312.12 KFO95920.1 - 0.24 11.6 4.1 0.97 9.6 1.6 2.5 2 1 1 3 3 3 0 cwf21 domain Cnd3 PF12719.7 KFO95921.1 - 3.8e-86 288.9 2.2 3.8e-86 288.9 2.2 2.6 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KFO95921.1 - 1.1e-08 35.4 7.9 0.018 15.5 0.4 5.3 5 0 0 5 5 5 3 HEAT repeats HEAT PF02985.22 KFO95921.1 - 4.7e-08 32.6 4.0 1.1 9.7 0.0 6.6 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 KFO95921.1 - 0.00047 20.6 7.5 2.6 8.7 0.6 4.3 3 1 1 4 4 4 3 HEAT-like repeat UVR PF02151.19 KFO95921.1 - 0.065 13.0 0.2 0.065 13.0 0.2 2.2 2 0 0 2 2 2 0 UvrB/uvrC motif Cnd1 PF12717.7 KFO95921.1 - 0.25 11.4 17.1 0.34 10.9 0.4 5.4 4 2 2 6 6 6 0 non-SMC mitotic condensation complex subunit 1 DUF4553 PF15090.6 KFO95922.1 - 1.7e-144 482.4 29.9 1.7e-144 482.4 29.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4553) Staphostatin_A PF09022.10 KFO95922.1 - 0.089 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Staphostatin A HTH_psq PF05225.16 KFO95923.1 - 5.8e-25 86.8 0.0 3e-16 58.9 0.0 2.4 2 0 0 2 2 2 2 helix-turn-helix, Psq domain Thioredoxin PF00085.20 KFO95924.1 - 2e-28 98.4 0.1 2.4e-28 98.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KFO95924.1 - 4.9e-08 33.4 0.1 5.5e-07 30.0 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFO95924.1 - 1.6e-05 25.0 0.0 2.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 KFO95924.1 - 0.00024 21.4 0.0 0.0083 16.4 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.6 KFO95924.1 - 0.00071 19.6 0.1 0.00099 19.1 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.21 KFO95924.1 - 0.0029 17.5 0.0 0.0037 17.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DSBA PF01323.20 KFO95924.1 - 0.013 15.3 0.0 0.31 10.8 0.0 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_9 PF14595.6 KFO95924.1 - 0.021 14.6 0.0 0.026 14.3 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin DUF836 PF05768.14 KFO95924.1 - 0.19 12.1 0.0 0.29 11.6 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Pyr_redox_3 PF13738.6 KFO95925.1 - 1.4e-34 119.7 0.0 1.1e-32 113.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFO95925.1 - 2.2e-10 40.3 0.0 3.8e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFO95925.1 - 2e-08 33.8 0.0 2.2e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KFO95925.1 - 1.5e-06 28.3 0.0 4.2e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KFO95925.1 - 7.2e-06 25.0 0.0 0.0024 16.7 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FMO-like PF00743.19 KFO95925.1 - 2.5e-05 22.9 0.0 8.7e-05 21.1 0.0 1.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like DAO PF01266.24 KFO95925.1 - 3.1e-05 23.7 0.0 0.0028 17.3 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFO95925.1 - 0.00026 20.3 0.0 0.00049 19.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KFO95925.1 - 0.0014 17.8 0.0 0.0038 16.4 0.0 1.6 1 1 1 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KFO95925.1 - 0.0038 17.8 0.0 1.2 9.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFO95925.1 - 0.0095 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KFO95925.1 - 0.044 13.1 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KFO95925.1 - 0.076 13.0 0.2 0.4 10.7 0.2 2.2 1 1 0 1 1 1 0 FAD-NAD(P)-binding Peptidase_C71 PF12386.8 KFO95925.1 - 0.085 12.5 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei YaiA PF16362.5 KFO95925.1 - 0.11 12.6 0.0 0.35 11.0 0.0 1.8 1 0 0 1 1 1 0 YaiA protein GIDA PF01134.22 KFO95925.1 - 0.11 11.5 0.0 1.1 8.3 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A eIF-3_zeta PF05091.12 KFO95926.1 - 1.1e-216 720.9 4.6 1.2e-216 720.7 4.6 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 KFO95926.1 - 0.00027 20.5 0.0 0.0053 16.3 0.0 2.4 1 1 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus UPF0697 PF15117.6 KFO95926.1 - 0.35 11.0 2.8 14 5.8 0.0 3.0 4 0 0 4 4 4 0 Uncharacterised protein family UPF0697 PMP22_Claudin PF00822.20 KFO95927.1 - 9.9e-58 194.7 1.8 1.3e-57 194.3 1.8 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFO95927.1 - 3.3e-21 75.9 0.9 5.2e-21 75.3 0.9 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Ras PF00071.22 KFO95928.1 - 2.5e-36 124.7 0.1 2.9e-36 124.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO95928.1 - 2.7e-17 63.1 0.0 5.3e-17 62.2 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KFO95928.1 - 0.00032 20.3 0.0 0.00038 20.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KFO95928.1 - 0.00045 19.7 0.0 0.00051 19.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFO95928.1 - 0.0088 16.1 0.0 0.015 15.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFO95928.1 - 0.021 14.7 0.0 0.17 11.8 0.0 2.1 2 1 0 2 2 2 0 RsgA GTPase TniB PF05621.11 KFO95928.1 - 0.16 11.4 0.0 1.7 8.0 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein EF-hand_1 PF00036.32 KFO95929.1 - 2.3e-13 48.6 2.2 2.1e-06 26.9 0.8 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFO95929.1 - 7.8e-13 48.7 0.4 1.6e-12 47.7 0.2 1.6 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KFO95929.1 - 3.6e-12 45.2 1.1 7.4e-05 22.1 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFO95929.1 - 1.6e-10 40.0 0.8 2e-05 24.2 0.1 2.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KFO95929.1 - 3.1e-09 36.5 0.6 1.3e-05 24.9 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFO95929.1 - 0.074 13.4 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Skp1 PF01466.19 KFO95929.1 - 0.093 12.9 0.1 0.22 11.6 0.1 1.7 1 0 0 1 1 1 0 Skp1 family, dimerisation domain EFhand_Ca_insen PF08726.10 KFO95929.1 - 0.1 12.7 0.1 0.34 11.0 0.0 1.8 2 0 0 2 2 2 0 Ca2+ insensitive EF hand PX PF00787.24 KFO95930.1 - 1.5e-17 63.6 0.0 2.5e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 KFO95930.1 - 1.6e-14 53.6 1.9 4.9e-14 52.0 0.8 2.1 2 0 0 2 2 2 1 PB1 domain SH3_1 PF00018.28 KFO95930.1 - 2.3e-11 43.1 0.0 4.6e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFO95930.1 - 3.3e-10 39.7 0.2 8.4e-10 38.4 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KFO95930.1 - 5.7e-09 35.5 0.0 1.8e-08 33.9 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain fn3 PF00041.21 KFO95931.1 - 6.8e-15 55.2 4.8 1.2e-07 32.0 0.0 5.0 5 1 0 5 5 5 3 Fibronectin type III domain IL6Ra-bind PF09240.10 KFO95931.1 - 4.5e-10 39.8 8.2 2.5e-06 27.8 0.2 2.8 3 0 0 3 3 3 2 Interleukin-6 receptor alpha chain, binding IL4Ra_N PF09238.10 KFO95931.1 - 3.4e-09 36.9 6.5 0.00021 21.5 1.2 3.6 3 1 1 4 4 4 2 Interleukin-4 receptor alpha chain, N-terminal EpoR_lig-bind PF09067.10 KFO95931.1 - 5.7e-07 29.7 8.2 8.8e-05 22.7 0.0 3.4 4 0 0 4 4 4 2 Erythropoietin receptor, ligand binding Tissue_fac PF01108.17 KFO95931.1 - 4.6e-05 23.2 5.5 0.00067 19.5 0.0 3.2 2 1 1 3 3 3 1 Tissue factor IL2RB_N1 PF18707.1 KFO95931.1 - 0.00051 20.5 9.0 0.0096 16.4 1.9 3.1 2 1 0 2 2 2 2 Interleukin-2 receptor subunit beta N-terminal domain 1 IL12p40_C PF10420.9 KFO95931.1 - 0.022 15.3 7.7 0.028 14.9 1.0 2.8 3 0 0 3 3 3 0 Cytokine interleukin-12p40 C-terminus TEX33 PF15400.6 KFO95932.1 - 1.8e-35 122.4 0.1 1.9e-35 122.3 0.1 1.0 1 0 0 1 1 1 1 Testis-expressed sequence 33 protein family Rhodanese PF00581.20 KFO95933.1 - 1.8e-24 86.3 0.0 2.2e-12 47.5 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Rhodanese PF00581.20 KFO95935.1 - 3.1e-30 104.8 0.0 1.6e-17 64.0 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain B12D PF06522.11 KFO95935.1 - 0.18 11.6 0.1 0.31 10.9 0.1 1.3 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit BTB_2 PF02214.22 KFO95936.1 - 7.7e-23 80.7 0.0 1.2e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KFO95936.1 - 0.015 15.6 0.0 0.023 14.9 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain SAM_LFY PF01698.16 KFO95936.1 - 0.085 12.8 0.1 0.22 11.5 0.0 1.6 2 0 0 2 2 2 0 Floricaula / Leafy protein SAM domain zf-RING_9 PF13901.6 KFO95936.1 - 0.087 12.8 0.8 1.5 8.8 0.0 2.1 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Peptidase_M90 PF06167.12 KFO95936.1 - 0.16 11.5 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 fn3 PF00041.21 KFO95937.1 - 3e-06 27.5 0.6 5.9e-06 26.5 0.6 1.5 1 1 0 1 1 1 1 Fibronectin type III domain C1q PF00386.21 KFO95938.1 - 1.3e-35 122.3 1.6 1.6e-35 122.0 1.6 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFO95938.1 - 6.9e-09 35.3 15.4 1e-08 34.8 15.4 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) 7tm_1 PF00001.21 KFO95939.1 - 1.2e-62 211.6 19.4 1.5e-62 211.3 19.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFO95939.1 - 4.5e-12 45.9 12.5 5.6e-12 45.6 12.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFO95939.1 - 3.2e-08 33.5 10.7 4.3e-08 33.1 10.7 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFO95939.1 - 1.2e-05 24.8 5.4 1.2e-05 24.8 5.4 2.1 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.9 KFO95939.1 - 0.00018 20.9 12.9 0.00061 19.2 0.2 2.5 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw Serpentine_r_xa PF03383.15 KFO95939.1 - 0.00025 21.1 0.7 0.00025 21.1 0.7 2.9 2 1 1 3 3 3 1 Caenorhabditis serpentine receptor-like protein, class xa TAS2R PF05296.13 KFO95939.1 - 0.022 13.9 12.8 0.096 11.8 12.8 1.9 1 1 0 1 1 1 0 Taste receptor protein (TAS2R) Rab5ip PF07019.12 KFO95939.1 - 0.45 11.1 5.3 0.18 12.4 0.9 2.5 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) Ras PF00071.22 KFO95940.1 - 2e-54 183.6 0.0 2.3e-54 183.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO95940.1 - 1.3e-22 80.2 0.0 1.8e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO95940.1 - 1.5e-07 31.1 0.0 2.4e-07 30.4 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family CagD PF16567.5 KFO95940.1 - 0.07 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Pathogenicity island component CagD Sec7 PF01369.20 KFO95941.1 - 5.1e-69 231.6 0.0 7.6e-69 231.1 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 KFO95941.1 - 1.6e-27 96.1 0.1 2.5e-27 95.4 0.1 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFO95941.1 - 4e-05 24.0 0.3 0.00013 22.3 0.3 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 KFO95941.1 - 0.0082 16.4 0.0 0.78 10.0 0.1 2.4 1 1 1 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 KFO95941.1 - 0.019 15.1 0.0 0.059 13.5 0.0 1.9 1 1 0 1 1 1 0 PH domain Syntaxin-6_N PF09177.11 KFO95941.1 - 0.077 13.6 0.8 2.5 8.7 0.0 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Pilosulin PF17499.2 KFO95941.1 - 0.15 12.2 0.1 0.5 10.6 0.0 1.8 2 0 0 2 2 2 0 Ant venom peptides LRR_8 PF13855.6 KFO95942.1 - 2.4e-24 84.9 15.7 6.4e-15 54.7 2.1 3.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_5 PF13306.6 KFO95942.1 - 2.8e-07 30.6 1.1 8.6e-07 29.0 0.5 2.1 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFO95942.1 - 1.1e-06 28.8 12.9 0.007 16.8 0.1 3.8 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) fn3 PF00041.21 KFO95942.1 - 0.01 16.1 0.1 0.027 14.8 0.1 1.7 1 0 0 1 1 1 0 Fibronectin type III domain LRR_9 PF14580.6 KFO95942.1 - 0.029 13.9 1.2 0.13 11.7 0.6 2.0 1 1 1 2 2 2 0 Leucine-rich repeat CD34_antigen PF06365.12 KFO95942.1 - 0.079 12.5 0.2 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family LRR_1 PF00560.33 KFO95942.1 - 1 10.2 6.8 12 6.9 0.4 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat Fringe PF02434.16 KFO95943.1 - 6.2e-107 356.7 0.0 7.3e-107 356.5 0.0 1.0 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 KFO95943.1 - 0.011 15.6 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 0 Galactosyltransferase Glyco_tranf_2_4 PF13704.6 KFO95943.1 - 0.12 12.9 0.2 0.25 11.9 0.2 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 BORG_CEP PF14957.6 KFO95944.1 - 6.4e-13 49.9 5.6 2.7e-11 44.7 5.6 2.2 1 1 0 1 1 1 1 Cdc42 effector PBD PF00786.28 KFO95944.1 - 3.3e-07 30.5 0.6 8.8e-07 29.2 0.6 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Gal-bind_lectin PF00337.22 KFO95945.1 - 1.3e-28 99.1 0.0 1.4e-28 99.0 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin SH3_1 PF00018.28 KFO95945.1 - 0.19 11.4 0.1 0.57 9.8 0.0 1.9 2 0 0 2 2 2 0 SH3 domain VHS PF00790.19 KFO95946.1 - 4.5e-37 127.1 1.8 2.2e-36 124.8 0.0 2.3 2 1 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 KFO95946.1 - 2.1e-30 105.3 0.1 4.8e-30 104.1 0.1 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.14 KFO95946.1 - 1.5e-22 79.6 5.7 1.5e-22 79.6 5.7 2.7 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 KFO95946.1 - 5.6e-21 73.9 3.7 1.8e-20 72.2 3.7 2.0 1 0 0 1 1 1 1 GGA N-GAT domain Ferritin PF00210.24 KFO95946.1 - 0.005 16.8 1.2 0.086 12.8 1.3 2.2 2 0 0 2 2 2 1 Ferritin-like domain Elf4 PF07011.11 KFO95946.1 - 0.0073 16.2 4.2 0.27 11.2 1.6 2.4 2 0 0 2 2 2 1 Early Flowering 4 domain DNA_ligase_A_N PF04675.14 KFO95946.1 - 0.032 14.5 2.7 8.1 6.7 0.4 3.1 2 1 1 3 3 3 0 DNA ligase N terminus RsbU_N PF08673.10 KFO95946.1 - 0.087 12.9 0.4 0.67 10.1 0.4 2.4 2 0 0 2 2 2 0 Phosphoserine phosphatase RsbU, N-terminal domain DUF1910 PF08928.10 KFO95946.1 - 0.14 12.2 0.4 0.3 11.1 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) PCRF PF03462.18 KFO95946.1 - 0.15 11.9 4.7 0.27 11.1 4.7 1.4 1 0 0 1 1 1 0 PCRF domain MCPsignal PF00015.21 KFO95946.1 - 0.23 11.2 1.9 0.36 10.6 1.9 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DASH_Dad4 PF08650.10 KFO95946.1 - 0.66 10.0 7.7 0.26 11.3 2.8 2.6 3 0 0 3 3 3 0 DASH complex subunit Dad4 DUF3450 PF11932.8 KFO95946.1 - 1.2 8.3 8.1 2.2 7.5 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) RhoGAP PF00620.27 KFO95947.1 - 1.2e-44 151.8 0.1 3e-44 150.5 0.1 1.7 1 0 0 1 1 1 1 RhoGAP domain BAR PF03114.18 KFO95947.1 - 2.5e-22 79.7 3.0 4.2e-22 79.0 3.0 1.3 1 0 0 1 1 1 1 BAR domain Hydrolase_like PF13242.6 KFO95947.1 - 2.8e-20 72.2 0.0 5.3e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 KFO95947.1 - 3.8e-07 30.3 2.1 0.00016 21.9 0.0 3.7 4 0 0 4 4 4 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFO95947.1 - 8.3e-05 23.0 0.0 0.00028 21.2 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Sec5 PF15469.6 KFO95947.1 - 0.0054 16.6 0.6 0.012 15.4 0.6 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 PGP_phosphatase PF09419.10 KFO95947.1 - 0.016 14.8 0.0 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Ribosomal_60s PF00428.19 KFO95947.1 - 0.66 10.6 7.2 1.3 9.7 0.8 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2076 PF09849.9 KFO95947.1 - 1.8 8.6 4.9 1.6 8.7 3.4 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Gal-bind_lectin PF00337.22 KFO95948.1 - 1.4e-28 99.1 0.0 1.6e-28 98.9 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin ChitinaseA_N PF08329.10 KFO95948.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Chitinase A, N-terminal domain ArfGap PF01412.18 KFO95949.1 - 1e-37 128.7 0.2 2.2e-37 127.7 0.2 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 KFO95949.1 - 2.6e-22 79.3 0.1 3.8e-12 46.6 0.0 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KFO95949.1 - 1.6e-06 28.5 1.5 0.00038 20.8 0.8 3.4 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 KFO95949.1 - 1.6e-06 28.3 0.8 0.029 14.7 0.0 3.1 3 1 0 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.6 KFO95949.1 - 1.6e-05 24.9 0.5 0.0029 17.7 0.1 3.2 2 1 0 2 2 2 1 PH domain Gag_p30 PF02093.16 KFO95949.1 - 0.1 12.1 0.0 0.31 10.5 0.0 1.7 1 1 1 2 2 2 0 Gag P30 core shell protein Nop25 PF09805.9 KFO95950.1 - 3.2e-11 43.9 11.2 3.2e-11 43.9 11.2 2.0 1 1 1 2 2 2 1 Nucleolar protein 12 (25kDa) Neur_chan_memb PF02932.16 KFO95950.1 - 1.5 8.8 3.1 2.3 8.2 3.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PH PF00169.29 KFO95951.1 - 3.2e-16 59.8 0.7 1e-15 58.2 0.3 2.1 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KFO95951.1 - 0.00045 20.6 7.0 0.0077 16.6 1.5 3.9 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 KFO95951.1 - 0.021 14.9 0.0 0.072 13.2 0.0 1.9 1 0 0 1 1 1 0 PH domain DUF2576 PF10845.8 KFO95951.1 - 0.06 12.9 0.7 1.8 8.2 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2576) Cellulose_synt PF03552.14 KFO95951.1 - 0.41 9.1 0.9 0.64 8.4 0.9 1.2 1 0 0 1 1 1 0 Cellulose synthase DUF1640 PF07798.11 KFO95951.1 - 3.7 7.6 36.1 9.6 6.2 0.1 4.3 1 1 1 3 3 3 0 Protein of unknown function (DUF1640) Aminotran_1_2 PF00155.21 KFO95952.1 - 1.8e-72 244.6 0.0 2.1e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFO95952.1 - 4.7e-07 29.1 0.0 1.1e-06 27.9 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KFO95952.1 - 7.9e-05 21.4 0.0 0.00012 20.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KFO95952.1 - 0.0022 17.3 0.1 0.0042 16.4 0.1 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KFO95952.1 - 0.061 12.6 0.2 0.4 9.9 0.2 2.0 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.20 KFO95952.1 - 0.11 11.1 0.0 1.4 7.5 0.0 2.1 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain 7tm_1 PF00001.21 KFO95953.1 - 1.4e-50 172.1 18.6 1.6e-50 171.9 18.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFO95953.1 - 1.7e-08 34.1 14.0 3.1e-06 26.7 14.0 2.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 KFO95953.1 - 2.3e-08 34.1 10.5 4.9e-07 29.8 10.5 2.1 1 1 0 1 1 1 1 Olfactory receptor Ank PF00023.30 KFO95954.1 - 1.3e-21 76.0 8.8 2.5e-09 37.2 0.2 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 KFO95954.1 - 5.2e-19 68.6 0.2 6.7e-10 39.4 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFO95954.1 - 1.8e-18 66.6 0.3 5.2e-08 33.3 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFO95954.1 - 6.7e-15 53.7 3.6 3.5e-06 26.9 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KFO95954.1 - 1.4e-14 54.0 1.9 1.1e-10 41.5 0.4 2.5 1 1 0 2 2 2 2 Ankyrin repeats (many copies) DUF2520 PF10728.9 KFO95954.1 - 0.11 12.3 0.1 0.35 10.7 0.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF2520) Paf67 PF10255.9 KFO95955.1 - 8.7e-169 561.8 7.6 1.4e-168 561.1 7.6 1.3 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KFO95955.1 - 0.0026 17.7 0.4 0.056 13.6 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFO95955.1 - 0.015 15.1 0.3 0.54 10.2 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO95955.1 - 0.029 14.6 0.1 0.08 13.2 0.1 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3585 PF12130.8 KFO95956.1 - 1.7e-42 144.8 13.8 2.7e-42 144.1 13.8 1.4 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain CH PF00307.31 KFO95956.1 - 1.5e-19 70.1 0.0 2.5e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain LIM PF00412.22 KFO95956.1 - 2.8e-08 33.9 4.4 5.4e-08 33.0 4.4 1.5 1 0 0 1 1 1 1 LIM domain CAMSAP_CH PF11971.8 KFO95956.1 - 3.2e-08 33.3 0.0 5.7e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain Roughex PF06020.11 KFO95956.1 - 0.036 13.2 6.0 0.08 12.0 6.0 1.5 1 0 0 1 1 1 0 Drosophila roughex protein zf-CSL PF05207.13 KFO95956.1 - 1.2 8.9 3.5 3.4 7.5 3.5 1.7 1 0 0 1 1 1 0 CSL zinc finger UPF0193 PF05250.11 KFO95957.1 - 1.2e-73 247.5 7.4 1.4e-73 247.3 7.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) DUF3404 PF11884.8 KFO95957.1 - 0.017 14.4 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) IGR PF09597.10 KFO95957.1 - 0.052 13.7 0.8 0.18 12.0 0.1 2.2 2 0 0 2 2 2 0 IGR protein motif RNA_pol_Rpb6 PF01192.22 KFO95958.1 - 9e-16 57.5 0.2 9e-16 57.5 0.2 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb6 BDHCT_assoc PF16204.5 KFO95958.1 - 0.2 11.3 1.0 0.24 11.0 1.0 1.2 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein Sox_N PF12444.8 KFO95959.1 - 7.8e-31 107.0 0.3 7.8e-31 107.0 0.3 2.7 3 0 0 3 3 3 1 Sox developmental protein N terminal HMG_box PF00505.19 KFO95959.1 - 5e-25 87.7 1.5 8.5e-25 87.0 1.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFO95959.1 - 7.7e-10 39.2 0.9 7.7e-10 39.2 0.9 1.8 2 0 0 2 2 2 1 HMG-box domain Arfaptin PF06456.13 KFO95960.1 - 6.8e-85 284.3 1.6 1.1e-84 283.6 1.6 1.3 1 0 0 1 1 1 1 Arfaptin-like domain PDZ PF00595.24 KFO95960.1 - 3.7e-11 43.2 0.2 6.5e-11 42.4 0.2 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFO95960.1 - 4.6e-08 32.8 0.1 8.7e-08 31.9 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFO95960.1 - 7.1e-06 26.3 1.0 1.4e-05 25.3 0.1 2.0 3 0 0 3 3 3 1 PDZ domain BAR PF03114.18 KFO95960.1 - 1.4e-05 24.9 1.2 0.00019 21.1 1.1 2.3 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 KFO95960.1 - 4.8e-05 23.2 1.4 0.058 13.1 0.2 2.3 2 0 0 2 2 2 2 BAR domain of APPL family GRASP55_65 PF04495.14 KFO95960.1 - 0.028 14.7 0.0 0.69 10.2 0.0 2.3 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain MFS_1 PF07690.16 KFO95961.1 - 3e-32 111.9 23.5 3.8e-32 111.6 23.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Ank_2 PF12796.7 KFO95962.1 - 1.7e-33 115.0 1.7 6.2e-10 39.5 0.0 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KFO95962.1 - 9.4e-30 101.7 5.9 0.00015 22.1 0.1 6.8 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.6 KFO95962.1 - 1.1e-29 102.4 4.2 2.5e-08 34.3 0.0 6.8 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFO95962.1 - 2.6e-28 97.7 3.4 1.3e-07 31.8 0.0 6.8 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFO95962.1 - 1.1e-23 80.8 7.7 0.0004 20.6 0.0 8.3 9 1 0 9 9 9 4 Ankyrin repeat Patatin PF01734.22 KFO95962.1 - 2.2e-18 67.2 1.5 1.5e-17 64.4 1.5 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase bZIP_Maf PF03131.17 KFO95963.1 - 1.1e-32 112.4 8.4 1.4e-32 112.0 8.4 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 KFO95963.1 - 0.00027 21.0 12.3 0.0018 18.3 12.3 2.2 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFO95963.1 - 0.0099 15.9 8.5 0.0099 15.9 8.5 2.5 2 1 2 4 4 4 1 Basic region leucine zipper DivIC PF04977.15 KFO95963.1 - 0.015 15.1 6.2 0.017 14.9 1.1 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF1192 PF06698.11 KFO95963.1 - 0.02 14.9 0.1 0.02 14.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Q_salvage PF10343.9 KFO95963.1 - 0.053 13.1 0.1 0.083 12.5 0.1 1.3 1 1 0 1 1 1 0 Potential Queuosine, Q, salvage protein family Cnn_1N PF07989.11 KFO95963.1 - 0.077 13.2 3.6 0.23 11.6 3.6 1.9 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 Nup54 PF13874.6 KFO95963.1 - 0.095 12.8 4.0 0.14 12.3 4.0 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 YabA PF06156.13 KFO95963.1 - 0.33 11.6 3.6 0.35 11.5 0.5 2.0 1 1 1 2 2 2 0 Initiation control protein YabA Solute_trans_a PF03619.16 KFO95964.1 - 5.2e-93 311.4 21.8 6.2e-93 311.1 21.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Pkinase PF00069.25 KFO95965.1 - 7.9e-21 74.6 0.0 1e-20 74.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO95965.1 - 1.7e-12 47.2 0.0 2.4e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFO95965.1 - 6.2e-10 38.4 0.1 9.8e-10 37.8 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFO95965.1 - 0.00035 20.6 0.4 0.0014 18.6 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KFO95965.1 - 0.042 12.8 0.1 0.071 12.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KFO95965.1 - 0.097 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IRK_C PF17655.1 KFO95966.1 - 1.3e-76 256.1 0.0 2e-76 255.5 0.0 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFO95966.1 - 1.1e-62 210.0 2.7 1.5e-62 209.6 2.7 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain IRK_N PF08466.10 KFO95966.1 - 0.037 14.2 4.4 0.037 14.2 4.4 2.0 2 0 0 2 2 2 0 Inward rectifier potassium channel N-terminal DUF92 PF01940.16 KFO95966.1 - 0.12 11.8 0.2 0.22 10.9 0.2 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF92 Ion_trans_2 PF07885.16 KFO95966.1 - 0.3 11.1 14.2 1.9 8.5 14.2 2.2 1 1 0 1 1 1 0 Ion channel ER_lumen_recept PF00810.18 KFO95967.1 - 8.9e-54 182.3 11.3 1.6e-53 181.5 11.3 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KFO95967.1 - 0.00023 20.9 6.2 0.03 14.1 0.8 3.1 2 1 0 2 2 2 2 PQ loop repeat DEAD PF00270.29 KFO95968.1 - 3.4e-50 170.3 0.0 2e-49 167.8 0.0 2.0 1 1 1 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFO95968.1 - 3.4e-31 107.9 0.0 1e-30 106.3 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFO95968.1 - 5.5e-05 23.2 0.0 0.0002 21.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF5335 PF17269.2 KFO95968.1 - 0.061 13.2 0.2 0.12 12.2 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5335) AAA_19 PF13245.6 KFO95968.1 - 0.071 13.4 0.0 8 6.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain Ferritin PF00210.24 KFO95968.1 - 0.1 12.5 1.0 0.24 11.3 1.0 1.7 1 1 0 1 1 1 0 Ferritin-like domain Microtub_bind PF13931.6 KFO95968.1 - 0.18 12.2 0.1 0.33 11.3 0.1 1.4 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding Rad51 PF08423.11 KFO95969.1 - 1.9e-110 368.1 0.0 2.5e-110 367.8 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KFO95969.1 - 2.3e-11 43.6 0.0 3.2e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KFO95969.1 - 1.6e-06 27.6 0.1 3.3e-06 26.6 0.1 1.6 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 KFO95969.1 - 1e-05 25.2 0.0 1.5e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 KFO95969.1 - 2.4e-05 24.8 1.3 4.2e-05 24.1 0.4 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain NRD1_2 PF01995.16 KFO95969.1 - 0.002 17.5 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 NrpR regulatory domains NRD1 and 2 DnaB_C PF03796.15 KFO95969.1 - 0.03 13.7 0.2 0.12 11.7 0.1 1.8 1 1 1 2 2 2 0 DnaB-like helicase C terminal domain Chibby PF14645.6 KFO95970.1 - 2.4e-49 166.6 1.2 2.7e-49 166.4 1.2 1.0 1 0 0 1 1 1 1 Chibby family Taxilin PF09728.9 KFO95970.1 - 0.00015 21.1 4.1 0.00019 20.7 4.1 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein JIP_LZII PF16471.5 KFO95970.1 - 0.18 12.0 9.0 0.25 11.6 9.0 1.2 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II TSC22 PF01166.18 KFO95970.1 - 1.6 9.1 9.1 0.52 10.7 4.4 2.1 1 1 1 2 2 2 0 TSC-22/dip/bun family Josephin PF02099.17 KFO95971.1 - 2.8e-29 102.3 0.5 6.8e-28 97.8 0.5 2.0 1 1 0 1 1 1 1 Josephin AhpC-TSA PF00578.21 KFO95971.1 - 0.11 12.4 0.1 0.66 9.9 0.0 2.1 2 0 0 2 2 2 0 AhpC/TSA family GTP_EFTU PF00009.27 KFO95972.1 - 1e-23 83.9 0.0 1.7e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KFO95972.1 - 5.7e-07 29.8 0.7 2.2e-06 27.9 0.1 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KFO95972.1 - 0.00039 20.7 0.3 0.0021 18.3 0.1 2.3 2 1 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KFO95972.1 - 0.0013 18.7 0.1 0.0041 17.2 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KFO95972.1 - 0.0019 18.0 0.0 3.2 7.5 0.0 3.6 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KFO95972.1 - 0.029 14.3 0.1 4.4 7.2 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 KFO95972.1 - 0.11 12.6 0.2 0.69 10.0 0.1 2.2 1 1 1 2 2 2 0 Dynamin family Arf PF00025.21 KFO95972.1 - 0.16 11.4 0.1 15 5.0 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family Sad1_UNC PF07738.13 KFO95973.1 - 1.9e-44 150.9 0.0 2.9e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Sun2_CC2 PF18580.1 KFO95973.1 - 3.2e-23 81.7 5.3 3.2e-23 81.7 5.3 2.7 3 0 0 3 3 2 1 SUN2 coiled coil domain 2 DUF1640 PF07798.11 KFO95973.1 - 0.011 15.8 0.3 0.011 15.8 0.3 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1640) DUF4618 PF15397.6 KFO95973.1 - 0.016 14.6 2.8 0.042 13.3 2.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) ZapB PF06005.12 KFO95973.1 - 0.032 14.7 1.5 0.032 14.7 1.5 3.6 2 1 1 3 3 3 0 Cell division protein ZapB Mer2 PF09074.10 KFO95973.1 - 0.043 13.6 0.7 0.16 11.7 0.1 1.9 1 1 1 2 2 2 0 Mer2 FlaC_arch PF05377.11 KFO95973.1 - 0.046 14.1 0.4 0.27 11.6 0.1 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Dynamin_M PF01031.20 KFO95973.1 - 0.12 11.6 0.2 0.2 10.8 0.2 1.3 1 0 0 1 1 1 0 Dynamin central region DUF4407 PF14362.6 KFO95973.1 - 0.17 11.2 7.0 0.11 11.8 0.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 KFO95973.1 - 0.18 11.8 0.2 0.58 10.2 0.1 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fez1 PF06818.15 KFO95973.1 - 0.25 11.7 8.6 0.47 10.9 8.6 1.4 1 0 0 1 1 1 0 Fez1 DivIC PF04977.15 KFO95973.1 - 0.49 10.2 8.7 1.3 8.9 0.1 3.6 3 0 0 3 3 3 0 Septum formation initiator COG2 PF06148.11 KFO95973.1 - 0.67 10.0 5.4 5 7.2 2.1 2.6 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 KFO95973.1 - 1.7 8.7 5.9 1 9.4 2.3 2.2 2 1 0 2 2 1 0 Protein of unknown function (DUF1664) FAM184 PF15665.5 KFO95973.1 - 2.5 7.8 8.0 2.1 8.1 6.3 1.7 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B Spc7 PF08317.11 KFO95973.1 - 2.5 6.9 6.7 5.9 5.7 6.7 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein HALZ PF02183.18 KFO95973.1 - 3.1 8.1 8.6 16 5.8 0.2 3.8 4 0 0 4 4 4 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 KFO95973.1 - 3.5 7.8 9.3 0.37 10.9 1.2 2.8 3 0 0 3 3 2 0 bZIP transcription factor Apolipoprotein PF01442.18 KFO95973.1 - 5 7.0 18.4 13 5.6 17.1 2.1 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain OmpH PF03938.14 KFO95973.1 - 8.9 6.6 13.1 3 8.2 4.4 2.5 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) Fam20C PF06702.12 KFO95974.1 - 2.4e-102 341.4 0.0 3.3e-102 340.9 0.0 1.2 1 0 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 FAM198 PF15051.6 KFO95974.1 - 0.038 12.9 0.0 0.063 12.1 0.0 1.4 1 0 0 1 1 1 0 FAM198 protein Dynein_light PF01221.18 KFO95975.1 - 7.4e-28 96.7 0.2 9.3e-28 96.4 0.2 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 DUF3109 PF11307.8 KFO95975.1 - 0.018 14.8 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3109) GARS_A PF01071.19 KFO95975.1 - 0.047 13.4 0.0 0.054 13.3 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Pentaxin PF00354.17 KFO95976.1 - 7.8e-34 117.1 0.0 1.1e-33 116.5 0.0 1.2 1 0 0 1 1 1 1 Pentaxin family CBX7_C PF17218.3 KFO95976.1 - 2.4e-14 52.7 1.2 4.9e-14 51.8 1.2 1.6 1 0 0 1 1 1 1 CBX family C-terminal motif Laminin_G_3 PF13385.6 KFO95976.1 - 7.6e-13 48.9 0.0 1.2e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Chromo PF00385.24 KFO95977.1 - 1.3e-11 44.2 0.7 2.7e-11 43.2 0.7 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CBX7_C PF17218.3 KFO95977.1 - 5.3e-11 42.0 2.1 1e-10 41.1 2.1 1.5 1 0 0 1 1 1 1 CBX family C-terminal motif PDGF PF00341.17 KFO95978.1 - 1.4e-24 86.2 13.1 2.8e-24 85.2 13.1 1.5 1 0 0 1 1 1 1 PDGF/VEGF domain PDGF_N PF04692.13 KFO95978.1 - 2.2e-12 47.6 2.7 2.3e-12 47.5 0.1 2.2 2 0 0 2 2 2 1 Platelet-derived growth factor, N terminal region Ribosomal_L3 PF00297.22 KFO95979.1 - 1.4e-191 636.3 11.4 1.7e-191 636.1 11.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 RTX PF02382.15 KFO95979.1 - 0.0072 16.0 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 N-terminal domain in RTX protein Glyco_transf_17 PF04724.13 KFO95981.1 - 8.4e-30 104.0 1.0 9e-25 87.4 0.0 3.3 4 0 0 4 4 4 3 Glycosyltransferase family 17 Mab-21 PF03281.14 KFO95982.1 - 2.1e-16 60.1 0.0 7.1e-15 55.1 0.0 2.1 1 1 1 2 2 2 2 Mab-21 protein bZIP_1 PF00170.21 KFO95983.1 - 6.2e-16 58.3 14.8 6.2e-16 58.3 14.8 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KFO95983.1 - 3.4e-07 30.2 12.4 6.5e-07 29.3 12.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Nop53 PF07767.11 KFO95983.1 - 0.0038 16.7 8.8 0.0048 16.3 8.8 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) ZapB PF06005.12 KFO95983.1 - 0.029 14.8 4.8 0.029 14.8 4.8 2.1 1 1 1 2 2 2 0 Cell division protein ZapB DUF3450 PF11932.8 KFO95983.1 - 0.14 11.4 8.8 0.25 10.6 8.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Syntaxin_2 PF14523.6 KFO95983.1 - 0.17 12.2 4.6 0.34 11.3 4.6 1.5 1 0 0 1 1 1 0 Syntaxin-like protein Laminin_II PF06009.12 KFO95983.1 - 0.35 10.9 7.0 0.62 10.1 7.0 1.3 1 0 0 1 1 1 0 Laminin Domain II bZIP_Maf PF03131.17 KFO95983.1 - 0.48 11.0 9.4 0.83 10.2 9.4 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Baculo_F PF12259.8 KFO95983.1 - 0.48 8.9 4.6 0.72 8.3 4.6 1.2 1 0 0 1 1 1 0 Baculovirus F protein UPF0242 PF06785.11 KFO95983.1 - 0.74 9.9 8.5 1.1 9.3 8.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 KFO95983.1 - 1.3 8.3 8.1 1.9 7.7 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 KFO95983.1 - 1.5 7.9 13.2 2.5 7.1 13.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0449 PF15136.6 KFO95983.1 - 1.9 9.0 7.0 1.8 9.1 5.4 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 AAA_13 PF13166.6 KFO95983.1 - 1.9 7.0 11.7 2.5 6.7 11.7 1.1 1 0 0 1 1 1 0 AAA domain DUF3682 PF12446.8 KFO95983.1 - 2.2 8.8 6.8 9.6 6.7 7.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3682) DUF724 PF05266.14 KFO95983.1 - 8.4 6.2 14.2 11 5.7 13.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) AROS PF15684.5 KFO95984.1 - 2.9e-32 112.0 4.8 3.1e-32 111.8 4.8 1.0 1 0 0 1 1 1 1 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 Ion_trans PF00520.31 KFO95985.1 - 5.2e-251 828.2 84.3 1.1e-77 260.6 16.3 4.1 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 KFO95985.1 - 2.2e-15 56.3 88.0 4.5e-08 32.2 3.7 9.8 6 3 3 9 9 9 6 Polycystin cation channel GRP PF07172.11 KFO95985.1 - 0.017 15.8 1.6 0.062 14.0 0.4 2.6 2 0 0 2 2 2 0 Glycine rich protein family TMEM208_SND2 PF05620.11 KFO95985.1 - 0.048 13.4 1.4 2.4 7.9 0.0 3.3 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 SieB PF14163.6 KFO95985.1 - 0.28 10.7 12.0 2.3 7.7 2.2 3.8 3 0 0 3 3 3 0 Super-infection exclusion protein B DUF3043 PF11241.8 KFO95985.1 - 7.9 6.5 10.0 22 5.1 0.0 4.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3043) FAM83 PF07894.12 KFO95986.1 - 6.6e-88 294.8 0.0 1e-87 294.2 0.0 1.3 1 0 0 1 1 1 1 FAM83 A-H PLDc_2 PF13091.6 KFO95986.1 - 9.8e-08 32.0 0.0 1.6e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 PLD-like domain DUF1465 PF07323.12 KFO95986.1 - 0.0093 15.8 1.7 0.045 13.6 0.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1465) Lyase_1 PF00206.20 KFO95987.1 - 1.2e-25 90.6 0.0 1.7e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KFO95987.1 - 1e-17 64.4 0.0 3e-17 62.9 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF4089 PF13318.6 KFO95987.1 - 0.00064 20.1 0.0 0.0017 18.8 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF4089) DUF1331 PF07048.11 KFO95987.1 - 0.056 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) RabGAP-TBC PF00566.18 KFO95988.1 - 2.5e-37 128.6 1.4 5.4e-37 127.5 1.4 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RUN PF02759.19 KFO95988.1 - 2.9e-31 108.2 0.2 6e-31 107.2 0.2 1.6 1 0 0 1 1 1 1 RUN domain SH3_1 PF00018.28 KFO95988.1 - 5.5e-12 45.1 0.1 1.3e-11 43.9 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFO95988.1 - 5.8e-10 38.9 0.0 1.6e-09 37.4 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFO95988.1 - 1.1e-09 37.8 0.0 2.8e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain RPEL PF02755.15 KFO95989.1 - 3.5e-23 80.6 12.5 2.8e-08 33.2 0.1 4.1 4 0 0 4 4 4 3 RPEL repeat SAP PF02037.27 KFO95989.1 - 8.3e-10 38.2 0.5 2.2e-09 36.8 0.5 1.8 1 0 0 1 1 1 1 SAP domain DUF722 PF05263.11 KFO95989.1 - 0.015 15.5 0.3 0.033 14.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF722) MPS2 PF17060.5 KFO95989.1 - 0.044 13.0 0.3 0.13 11.5 0.3 1.7 1 0 0 1 1 1 0 Monopolar spindle protein 2 Mito_carr PF00153.27 KFO95990.1 - 3.5e-53 177.5 1.4 2e-22 78.9 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Peptidase_M24 PF00557.24 KFO95991.1 - 1.4e-56 191.5 0.0 1.9e-56 191.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KFO95991.1 - 5.8e-37 126.2 0.0 1e-36 125.4 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain zf-rbx1 PF12678.7 KFO95992.1 - 6.6e-26 90.4 12.9 7.8e-26 90.1 12.9 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFO95992.1 - 1.1e-15 57.5 10.7 1.3e-15 57.2 10.7 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KFO95992.1 - 5.4e-07 29.8 14.9 2.9e-05 24.3 14.9 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFO95992.1 - 2.3e-05 24.1 3.2 2.3e-05 24.1 3.2 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFO95992.1 - 0.00038 20.3 12.2 0.0083 16.0 12.2 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFO95992.1 - 0.031 14.1 11.4 0.17 11.8 5.2 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KFO95992.1 - 0.039 13.6 5.3 0.039 13.6 5.3 2.2 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KFO95992.1 - 0.14 12.4 9.4 0.87 9.8 9.6 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_11 PF17123.5 KFO95992.1 - 0.14 11.9 16.6 17 5.2 16.6 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 KFO95992.1 - 0.17 11.9 8.3 0.71 9.9 8.3 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFO95992.1 - 3.1 8.0 9.4 0.39 10.9 0.7 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KFO95992.1 - 3.9 7.5 13.6 40 4.3 13.6 2.5 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING-like PF08746.11 KFO95992.1 - 4.2 7.7 13.0 52 4.3 13.0 2.3 1 1 0 1 1 1 0 RING-like domain LRR_8 PF13855.6 KFO95994.1 - 1.3e-38 130.6 7.9 3.9e-16 58.6 0.5 2.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFO95994.1 - 1.9e-10 40.8 0.0 7e-05 23.1 0.0 2.5 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFO95994.1 - 2.2e-05 24.4 2.5 14 6.7 0.0 4.8 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_5 PF13306.6 KFO95994.1 - 0.0033 17.4 0.0 0.0039 17.1 0.0 1.1 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFO95994.1 - 0.0057 16.2 0.0 0.023 14.2 0.0 1.8 1 1 0 1 1 1 1 Leucine-rich repeat Xan_ur_permease PF00860.20 KFO95995.1 - 1.1e-89 300.8 23.3 1.6e-89 300.3 23.3 1.1 1 0 0 1 1 1 1 Permease family WD40 PF00400.32 KFO95996.1 - 1.2e-12 48.1 5.7 0.0033 18.2 0.0 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO95996.1 - 9.2e-09 35.5 0.0 0.00021 21.5 0.0 3.0 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFO95996.1 - 7.4e-05 21.9 0.2 0.00039 19.5 0.0 2.2 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4313 PF14190.6 KFO95996.1 - 0.092 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4313) TM140 PF14985.6 KFO95997.1 - 4.1e-23 81.9 1.2 4.6e-23 81.7 1.2 1.0 1 0 0 1 1 1 1 TM140 protein family Pepdidase_M14_N PF18027.1 KFO95998.1 - 6.7e-21 74.7 2.6 1.4e-20 73.6 2.6 1.6 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 KFO95998.1 - 9.8e-19 68.2 0.0 3.3e-18 66.5 0.0 1.8 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 KFO95998.1 - 0.00055 19.1 0.0 0.00078 18.6 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family PDE6_gamma PF04868.12 KFO95999.1 - 1.3e-46 156.8 0.6 1.4e-46 156.7 0.6 1.0 1 0 0 1 1 1 1 Retinal cGMP phosphodiesterase, gamma subunit Rho_GDI PF02115.17 KFO96000.1 - 6.1e-76 254.5 0.2 6.9e-76 254.3 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Thioredoxin_6 PF13848.6 KFO96001.1 - 4.9e-21 75.5 0.2 6.2e-21 75.1 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain ART PF01129.18 KFO96004.1 - 2.9e-50 170.6 2.5 3.3e-50 170.4 2.5 1.0 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase ADPrib_exo_Tox PF03496.14 KFO96004.1 - 0.00025 20.4 0.0 0.00035 20.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosyltransferase exoenzyme SGT1 PF07093.11 KFO96004.1 - 0.045 12.2 0.1 0.062 11.7 0.1 1.1 1 0 0 1 1 1 0 SGT1 protein YchF-GTPase_C PF06071.13 KFO96004.1 - 0.065 13.4 0.1 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF933) DUF4533 PF15047.6 KFO96005.1 - 7.9e-20 71.4 0.9 8.5e-20 71.3 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4533) DUF4533 PF15047.6 KFO96006.1 - 1.2e-63 214.7 8.4 8.6e-62 208.7 8.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4533) DNA_repr_REX1B PF14966.6 KFO96006.1 - 0.0057 17.3 3.5 0.021 15.5 0.6 2.3 2 0 0 2 2 2 1 DNA repair REX1-B SLATT_1 PF18181.1 KFO96006.1 - 0.038 13.9 0.9 0.86 9.6 0.0 2.4 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DUF2408 PF10303.9 KFO96006.1 - 0.27 11.8 5.8 0.48 11.0 2.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Wbp11 PF09429.10 KFO96007.1 - 8.6e-22 77.3 13.8 8.6e-22 77.3 13.8 3.1 3 1 0 3 3 3 1 WW domain binding protein 11 Histone_H2A_C PF16211.5 KFO96008.1 - 3.6e-20 71.4 1.1 5.6e-20 70.8 1.1 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFO96008.1 - 9e-16 58.4 0.0 1.1e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFO96008.1 - 2.5e-05 24.5 0.0 3.2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Linker_histone PF00538.19 KFO96009.1 - 4.9e-21 74.9 1.2 4.9e-21 74.9 1.2 1.9 2 0 0 2 2 2 1 linker histone H1 and H5 family Histone PF00125.24 KFO96010.1 - 6.8e-26 91.2 0.2 8.4e-26 90.9 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFO96010.1 - 8.9e-07 29.1 0.7 1.8e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KFO96010.1 - 0.0031 18.0 0.0 0.006 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KFO96010.1 - 0.0034 17.4 0.3 0.0039 17.2 0.3 1.2 1 0 0 1 1 1 1 YscO-like protein CENP-T_C PF15511.6 KFO96011.1 - 1.8e-08 34.5 0.1 2.2e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KFO96011.1 - 2.5e-05 24.4 0.2 3.5e-05 23.9 0.2 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KFO96011.1 - 4.6e-05 23.7 0.1 6.1e-05 23.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 KFO96011.1 - 0.00017 21.9 0.3 0.00019 21.8 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFO96011.1 - 0.00028 21.1 0.1 0.00046 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFO96011.1 - 0.0059 16.7 0.0 0.0067 16.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KFO96011.1 - 0.024 14.6 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KFO96011.1 - 0.21 11.4 0.1 0.25 11.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone_H2A_C PF16211.5 KFO96013.1 - 3e-20 71.7 1.1 4.6e-20 71.0 1.1 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFO96013.1 - 1.4e-11 44.8 0.0 1.7e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFO96013.1 - 0.025 14.9 0.0 0.032 14.5 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFO96014.1 - 4.6e-26 91.7 0.3 5.6e-26 91.4 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFO96014.1 - 9.5e-07 29.0 1.0 1.8e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KFO96014.1 - 0.0034 17.8 0.0 0.006 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KFO96014.1 - 0.0038 17.3 0.3 0.0045 17.0 0.3 1.1 1 0 0 1 1 1 1 YscO-like protein Histone PF00125.24 KFO96015.1 - 4.5e-35 120.9 0.9 4.8e-35 120.8 0.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KFO96015.1 - 2.2e-05 24.5 0.1 2.6e-05 24.3 0.1 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KFO96015.1 - 0.00013 22.2 0.0 0.00017 21.9 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KFO96015.1 - 0.0043 17.3 0.0 0.0056 16.9 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFO96015.1 - 0.042 13.9 0.0 0.044 13.9 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone_H2A_C PF16211.5 KFO96016.1 - 2.9e-20 71.7 1.8 5e-20 70.9 1.8 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFO96016.1 - 5e-17 62.5 0.0 6.5e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFO96016.1 - 1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFO96017.1 - 4e-26 91.9 0.4 4.9e-26 91.6 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFO96017.1 - 9.4e-07 29.0 0.7 1.8e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KFO96017.1 - 0.0029 18.1 0.0 0.0056 17.2 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KFO96017.1 - 0.0067 16.5 0.2 0.008 16.2 0.2 1.1 1 0 0 1 1 1 1 YscO-like protein Linker_histone PF00538.19 KFO96018.1 - 2e-20 72.9 1.5 2e-20 72.9 1.5 1.9 2 1 0 2 2 2 1 linker histone H1 and H5 family Mitofilin PF09731.9 KFO96018.1 - 1.4 7.7 27.7 1.5 7.6 27.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CENP-T_C PF15511.6 KFO96019.1 - 5e-08 33.0 0.1 5.8e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KFO96019.1 - 2e-05 24.7 0.1 2.8e-05 24.2 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KFO96019.1 - 5e-05 23.6 0.1 5.9e-05 23.4 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 KFO96019.1 - 0.00014 22.2 0.3 0.00016 22.0 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFO96019.1 - 0.00023 21.4 0.1 0.00037 20.7 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFO96019.1 - 0.0088 16.1 0.0 0.0095 16.0 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KFO96019.1 - 0.024 14.6 0.0 0.036 14.1 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 KFO96021.1 - 1.2e-33 116.2 0.7 1.3e-33 116.1 0.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KFO96021.1 - 2.5e-05 24.4 0.1 2.7e-05 24.2 0.1 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KFO96021.1 - 0.0001 22.6 0.0 0.00012 22.4 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KFO96021.1 - 0.0058 16.9 0.0 0.0069 16.6 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFO96021.1 - 0.034 14.2 0.0 0.035 14.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 KFO96022.1 - 6.8e-54 181.7 2.3 7.6e-54 181.6 2.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KFO96022.1 - 8.4e-05 22.6 0.3 0.00015 21.8 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KFO96022.1 - 0.00019 22.0 1.2 0.00023 21.8 1.2 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 KFO96022.1 - 0.00042 20.6 0.0 0.00064 20.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KFO96022.1 - 0.011 16.0 0.1 0.022 15.0 0.1 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFO96022.1 - 0.11 12.6 0.1 0.21 11.7 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KFO96023.1 - 1.8e-08 34.5 0.1 2.2e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KFO96023.1 - 2.5e-05 24.4 0.2 3.5e-05 23.9 0.2 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KFO96023.1 - 4.6e-05 23.7 0.1 6.1e-05 23.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 KFO96023.1 - 0.00017 21.9 0.3 0.00019 21.8 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFO96023.1 - 0.00028 21.1 0.1 0.00046 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFO96023.1 - 0.0059 16.7 0.0 0.0067 16.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KFO96023.1 - 0.024 14.6 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KFO96023.1 - 0.21 11.4 0.1 0.25 11.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone_H2A_C PF16211.5 KFO96025.1 - 4.1e-20 71.2 1.1 7.1e-20 70.4 1.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFO96025.1 - 2.7e-17 63.4 0.0 3.4e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFO96025.1 - 3.3e-05 24.1 0.0 4.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribosomal_L27A PF00828.19 KFO96025.1 - 0.047 14.4 0.1 0.056 14.1 0.1 1.2 1 0 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Histone PF00125.24 KFO96026.1 - 5.3e-26 91.5 0.2 6.1e-26 91.3 0.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFO96026.1 - 8.3e-07 29.2 0.7 1.5e-06 28.4 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KFO96026.1 - 0.0027 18.2 0.0 0.0048 17.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KFO96026.1 - 0.0027 17.8 0.1 0.0032 17.5 0.1 1.1 1 0 0 1 1 1 1 YscO-like protein Histone_H2A_C PF16211.5 KFO96027.1 - 2.1e-20 72.1 1.1 3.2e-20 71.6 1.1 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFO96027.1 - 6.5e-08 33.0 0.2 8e-08 32.7 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Linker_histone PF00538.19 KFO96028.1 - 1.2e-21 76.8 0.4 1.2e-21 76.8 0.4 2.5 2 1 0 2 2 2 1 linker histone H1 and H5 family Histone_H2A_C PF16211.5 KFO96029.1 - 2.2e-20 72.1 1.1 3.5e-20 71.4 1.1 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFO96029.1 - 2.5e-10 40.8 0.0 3.4e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KFO96030.1 - 2.2e-20 72.1 1.1 3.5e-20 71.4 1.1 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFO96030.1 - 2.5e-10 40.8 0.0 3.4e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Linker_histone PF00538.19 KFO96031.1 - 4.7e-13 49.3 1.0 4.7e-13 49.3 1.0 2.2 2 0 0 2 2 2 1 linker histone H1 and H5 family DUF2457 PF10446.9 KFO96031.1 - 4.9 6.2 18.2 6.4 5.8 18.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) ApoL PF05461.11 KFO96032.1 - 2e-13 50.4 2.5 2e-13 50.4 2.5 1.6 2 0 0 2 2 2 1 Apolipoprotein L SseC PF04888.12 KFO96032.1 - 0.00078 19.1 1.5 0.84 9.2 1.4 2.1 1 1 1 2 2 2 2 Secretion system effector C (SseC) like family Prefoldin PF02996.17 KFO96032.1 - 0.23 11.4 2.1 8.5 6.3 0.0 2.7 3 0 0 3 3 3 0 Prefoldin subunit Takusan PF04822.13 KFO96032.1 - 0.44 10.5 2.5 0.51 10.3 0.3 2.1 2 0 0 2 2 2 0 Takusan DEAD PF00270.29 KFO96033.1 - 6.2e-48 162.9 0.2 9.7e-48 162.2 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFO96033.1 - 2.2e-32 111.7 0.2 2e-31 108.6 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFO96033.1 - 3.8e-06 27.0 0.0 7.9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KFO96033.1 - 0.0079 15.9 0.0 0.034 13.8 0.0 2.0 3 1 0 3 3 3 1 SWI2/SNF2 ATPase ICAM_N PF03921.14 KFO96033.1 - 0.16 11.7 0.2 2.9 7.6 0.1 2.4 2 0 0 2 2 2 0 Intercellular adhesion molecule (ICAM), N-terminal domain 7tm_3 PF00003.22 KFO96034.1 - 1.3e-26 93.8 33.2 1.6e-26 93.5 33.2 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF1772 PF08592.11 KFO96034.1 - 0.34 11.2 12.1 2.3 8.5 2.2 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) ABC2_membrane_5 PF13346.6 KFO96034.1 - 0.59 9.6 34.4 0.2 11.2 16.9 2.3 1 1 1 2 2 2 0 ABC-2 family transporter protein DUF1345 PF07077.11 KFO96034.1 - 2.4 7.8 13.2 8.1 6.1 8.5 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1345) DUF1129 PF06570.11 KFO96034.1 - 5.3 6.5 20.5 0.95 8.9 4.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) SOUL PF04832.12 KFO96035.1 - 2.3e-38 132.0 0.0 2.5e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein DUF1409 PF07197.12 KFO96036.1 - 0.015 15.2 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) PQQ_2 PF13360.6 KFO96037.1 - 6.3e-07 29.2 0.0 0.0048 16.5 0.0 2.3 2 0 0 2 2 2 2 PQQ-like domain VCBS PF13517.6 KFO96037.1 - 8.5e-06 26.3 0.1 0.23 12.1 0.0 3.4 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KFO96037.1 - 0.00013 22.0 6.1 0.047 13.8 0.3 3.1 2 1 0 2 2 2 2 FG-GAP repeat GSG-1 PF07803.11 KFO96038.1 - 3.1e-50 169.0 0.1 8.2e-50 167.6 0.0 1.8 2 0 0 2 2 2 1 GSG1-like protein PMP22_Claudin PF00822.20 KFO96038.1 - 2.2e-07 30.9 7.0 2.7e-07 30.6 2.7 2.4 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFO96038.1 - 0.00014 21.6 9.9 0.00047 20.0 9.9 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.12 KFO96038.1 - 1 8.8 12.3 1.2 8.5 0.0 2.7 3 1 0 3 3 3 0 Clc-like PMP22_Claudin PF00822.20 KFO96039.1 - 2e-44 151.4 20.3 2.3e-44 151.2 20.3 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFO96039.1 - 0.002 17.9 16.3 0.002 17.9 16.3 3.0 1 1 2 3 3 3 1 PMP-22/EMP/MP20/Claudin tight junction DUF4064 PF13273.6 KFO96039.1 - 0.0071 16.6 21.8 0.034 14.4 11.3 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF4064) DUF998 PF06197.13 KFO96039.1 - 0.16 11.6 10.2 0.028 14.0 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF998) Amastin PF07344.11 KFO96039.1 - 0.17 11.8 22.3 0.63 9.9 21.5 2.0 1 1 0 1 1 1 0 Amastin surface glycoprotein Claudin_3 PF06653.11 KFO96039.1 - 0.2 11.6 23.4 0.37 10.7 23.4 1.5 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DUF1180 PF06679.12 KFO96039.1 - 0.21 12.0 0.1 0.32 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) 7TMR-DISM_7TM PF07695.11 KFO96039.1 - 0.44 10.4 28.8 6.5 6.6 26.6 3.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling PalH PF08733.10 KFO96039.1 - 1.4 7.8 17.0 0.099 11.6 8.4 2.0 2 0 0 2 2 2 0 PalH/RIM21 NMDAR2_C PF10565.9 KFO96040.1 - 1.5e-228 761.0 14.8 1.7e-228 760.8 14.8 1.1 1 0 0 1 1 1 1 N-methyl D-aspartate receptor 2B3 C-terminus Lig_chan PF00060.26 KFO96040.1 - 1.3e-33 116.0 0.1 2.1e-33 115.3 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFO96040.1 - 7.9e-31 106.6 0.1 5.5e-30 103.9 0.1 2.1 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFO96040.1 - 1.1e-24 87.1 0.0 1.8e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 KFO96040.1 - 9.2e-11 41.4 0.0 8.3e-09 35.0 0.0 2.3 1 1 0 1 1 1 1 Receptor family ligand binding region DUF4013 PF13197.6 KFO96040.1 - 3.2 7.5 6.9 3.5 7.4 4.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4013) ATF7IP_BD PF16788.5 KFO96041.1 - 8.7e-66 222.2 5.6 8.7e-66 222.2 5.6 3.8 4 1 0 5 5 5 1 ATF-interacting protein binding domain fn3_4 PF16794.5 KFO96041.1 - 1.5e-40 137.3 0.0 2.8e-40 136.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin-III type domain Phospholip_B PF04916.13 KFO96042.1 - 4.2e-181 603.1 4.0 5.1e-181 602.9 4.0 1.1 1 0 0 1 1 1 1 Phospholipase B Nucleo_LEF-12 PF06256.11 KFO96042.1 - 0.0052 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Nucleopolyhedrovirus LEF-12 protein Guanylate_cyc PF00211.20 KFO96043.1 - 1.3e-66 223.7 0.0 2.6e-66 222.8 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 KFO96043.1 - 1e-34 120.0 0.0 2.9e-34 118.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO96043.1 - 2.3e-28 99.3 0.1 4.8e-28 98.3 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain ANF_receptor PF01094.28 KFO96043.1 - 8.4e-08 31.7 0.0 9.4e-07 28.2 0.0 2.2 1 1 0 1 1 1 1 Receptor family ligand binding region TPR_19 PF14559.6 KFO96044.1 - 9.6e-20 70.9 7.3 2.4e-05 24.8 0.5 5.7 4 1 1 5 5 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO96044.1 - 5.3e-12 45.8 20.2 0.0014 18.8 0.1 5.4 4 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KFO96044.1 - 1.1e-10 40.7 27.3 0.032 14.3 0.1 8.8 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFO96044.1 - 1.5e-08 34.7 7.1 0.63 11.0 0.0 6.3 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFO96044.1 - 3.2e-08 33.2 10.2 0.0021 18.1 0.0 6.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFO96044.1 - 1.8e-06 27.9 3.9 0.0041 17.4 0.0 5.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFO96044.1 - 2.1e-06 27.3 18.1 0.0063 16.3 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFO96044.1 - 2.2e-06 27.7 1.9 0.013 15.6 0.3 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFO96044.1 - 6.5e-06 26.7 5.4 0.036 14.7 0.0 5.3 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFO96044.1 - 5e-05 23.7 14.0 0.18 12.5 0.0 8.1 9 0 0 9 9 9 1 Tetratricopeptide repeat PPR PF01535.20 KFO96044.1 - 6.8e-05 22.8 0.5 0.46 10.8 0.0 4.7 5 0 0 5 5 4 1 PPR repeat TPR_7 PF13176.6 KFO96044.1 - 0.0002 21.2 9.3 1.2 9.3 0.3 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat Coatomer_E PF04733.14 KFO96044.1 - 0.00059 19.4 2.5 0.0011 18.5 0.6 2.3 2 2 0 2 2 2 1 Coatomer epsilon subunit TPR_12 PF13424.6 KFO96044.1 - 0.0007 19.8 14.9 1 9.7 0.0 6.5 8 1 0 8 8 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 KFO96044.1 - 0.0011 19.3 0.0 24 5.9 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR_2 PF13041.6 KFO96044.1 - 0.0057 16.8 1.0 1.2 9.4 0.1 3.6 4 1 1 5 5 5 1 PPR repeat family MA3 PF02847.17 KFO96044.1 - 0.086 12.8 1.2 13 5.8 0.0 3.9 4 0 0 4 4 4 0 MA3 domain Fis1_TPR_C PF14853.6 KFO96044.1 - 0.11 12.6 5.0 6 7.0 0.2 4.4 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KFO96044.1 - 0.19 11.6 14.2 13 5.8 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat UBN_AB PF14075.6 KFO96045.1 - 2.1e-81 272.7 3.3 2.1e-81 272.7 3.3 2.4 2 1 0 2 2 2 1 Ubinuclein conserved middle domain HUN PF08729.10 KFO96045.1 - 1.7e-19 69.6 0.4 3.9e-19 68.4 0.4 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Complex1_LYR_2 PF13233.6 KFO96046.1 - 0.00049 20.8 0.6 0.0006 20.5 0.6 1.1 1 0 0 1 1 1 1 Complex1_LYR-like LUC7 PF03194.15 KFO96047.1 - 5.4e-70 235.9 14.0 5.4e-70 235.9 14.0 2.4 1 1 1 2 2 2 1 LUC7 N_terminus Globin PF00042.22 KFO96048.1 - 3e-31 108.2 0.3 4.7e-31 107.6 0.2 1.4 2 0 0 2 2 2 1 Globin BEN PF10523.9 KFO96048.1 - 0.013 15.7 0.1 0.031 14.5 0.0 1.7 2 0 0 2 2 2 0 BEN domain IL12 PF03039.14 KFO96048.1 - 0.052 12.9 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Interleukin-12 alpha subunit Sulfotransfer_3 PF13469.6 KFO96048.1 - 0.13 12.6 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase family MIEAP PF16026.5 KFO96049.1 - 1.9e-06 28.2 0.7 2.3e-06 28.0 0.7 1.1 1 0 0 1 1 1 1 Mitochondria-eating protein FliT PF05400.13 KFO96049.1 - 0.011 16.5 0.4 0.021 15.6 0.4 1.3 1 0 0 1 1 1 0 Flagellar protein FliT Anthrax-tox_M PF09156.10 KFO96049.1 - 0.021 14.2 0.1 0.026 13.9 0.1 1.1 1 0 0 1 1 1 0 Anthrax toxin lethal factor, middle domain RRM_1 PF00076.22 KFO96050.1 - 1.1e-10 41.2 0.0 2.8e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRP7 PF12923.7 KFO96051.1 - 2.1e-35 121.4 10.8 3.1e-35 120.9 10.8 1.3 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF5093 PF17011.5 KFO96051.1 - 0.0042 17.4 0.9 0.0098 16.2 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5093) RRM_1 PF00076.22 KFO96051.1 - 0.02 14.7 0.1 0.86 9.5 0.0 2.7 1 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trans_reg_C PF00486.28 KFO96051.1 - 0.048 13.7 1.8 0.28 11.3 0.7 2.3 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal Vir_act_alpha_C PF10400.9 KFO96051.1 - 0.51 11.1 0.0 0.51 11.1 0.0 2.5 2 1 0 2 2 2 0 Virulence activator alpha C-term Abhydrolase_1 PF00561.20 KFO96052.1 - 6.3e-21 75.2 0.1 2.7e-20 73.1 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFO96052.1 - 1.7e-17 64.7 0.2 2.4e-17 64.3 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFO96052.1 - 8.4e-12 44.9 0.0 4e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KFO96052.1 - 0.0016 18.6 0.6 0.033 14.3 0.1 2.3 2 1 0 2 2 2 1 Thioesterase domain Lipase_3 PF01764.25 KFO96052.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 KFO96052.1 - 0.067 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.7 KFO96052.1 - 0.14 11.9 0.0 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family SH2 PF00017.24 KFO96053.1 - 4.2e-06 26.8 0.0 5.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 SH2 domain Agarase_CBM PF17992.1 KFO96054.1 - 0.072 12.7 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 Agarase CBM like domain zf-HC5HC2H PF13771.6 KFO96055.1 - 7.2e-09 35.8 5.9 2.1e-08 34.3 5.9 1.9 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFO96055.1 - 3.7e-08 33.5 1.4 1.1e-07 32.0 1.4 1.7 1 0 0 1 1 1 1 PHD-zinc-finger like domain p450 PF00067.22 KFO96056.1 - 7.3e-124 414.0 0.1 2.7e-123 412.2 0.1 1.7 1 1 0 1 1 1 1 Cytochrome P450 Complex1_LYR PF05347.15 KFO96057.1 - 6.6e-07 29.3 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF4252 PF14060.6 KFO96057.1 - 0.14 12.0 0.1 0.19 11.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) PH PF00169.29 KFO96058.1 - 1.7e-16 60.7 0.0 2.3e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFO96058.1 - 1.6e-05 25.1 0.0 2.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFO96058.1 - 0.036 14.5 1.0 1.2 9.6 1.0 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain ASCH PF04266.14 KFO96058.1 - 0.16 12.6 0.1 0.27 11.8 0.1 1.4 1 0 0 1 1 1 0 ASCH domain Melibiase_2 PF16499.5 KFO96059.1 - 1.4e-155 516.6 0.5 1.6e-155 516.5 0.5 1.0 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase PF02065.18 KFO96059.1 - 8.6e-06 24.9 0.0 1.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Melibiase Glyco_hydro_97 PF10566.9 KFO96059.1 - 0.01 15.1 0.0 0.068 12.4 0.0 1.9 2 0 0 2 2 2 0 Glycoside hydrolase 97 GRAM PF02893.20 KFO96060.1 - 8.3e-13 48.2 0.0 1.1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 GRAM domain Septin PF00735.18 KFO96061.1 - 5.4e-116 386.8 1.6 6.3e-116 386.6 1.6 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFO96061.1 - 3.8e-08 33.4 0.0 6.9e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFO96061.1 - 2.9e-06 27.3 3.7 2.3e-05 24.3 1.4 2.5 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KFO96061.1 - 2e-05 24.2 0.5 0.013 15.0 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KFO96061.1 - 3.7e-05 23.2 0.1 6.8e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KFO96061.1 - 0.00034 20.7 7.0 0.081 13.0 0.8 3.4 2 2 2 4 4 4 2 Dynamin family AAA_16 PF13191.6 KFO96061.1 - 0.00086 19.7 0.0 0.0015 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KFO96061.1 - 0.0012 19.4 0.2 0.0042 17.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter Roc PF08477.13 KFO96061.1 - 0.0013 19.0 0.2 0.0029 17.8 0.2 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KFO96061.1 - 0.0016 18.7 0.0 0.0044 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Ras PF00071.22 KFO96061.1 - 0.0044 16.6 0.2 0.014 15.0 0.1 1.9 1 1 0 2 2 2 1 Ras family AAA_24 PF13479.6 KFO96061.1 - 0.0046 16.7 0.2 0.19 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KFO96061.1 - 0.0065 15.7 0.9 0.0083 15.3 0.2 1.6 2 0 0 2 2 2 1 NB-ARC domain FtsK_SpoIIIE PF01580.18 KFO96061.1 - 0.0067 15.8 0.8 0.0088 15.4 0.1 1.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_29 PF13555.6 KFO96061.1 - 0.018 14.7 0.1 0.032 13.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 KFO96061.1 - 0.024 13.8 3.6 0.074 12.2 3.6 1.9 1 1 0 1 1 1 0 G-protein alpha subunit Sigma54_activat PF00158.26 KFO96061.1 - 0.031 14.0 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.9 KFO96061.1 - 0.032 14.0 0.1 1.2 8.9 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation IIGP PF05049.13 KFO96061.1 - 0.046 12.8 0.8 0.091 11.8 0.1 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.18 KFO96061.1 - 0.05 13.1 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 KFO96061.1 - 0.058 12.9 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 KFO96061.1 - 0.097 11.8 0.1 0.19 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KFO96061.1 - 0.12 12.8 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KFO96061.1 - 0.16 12.1 0.1 0.51 10.5 0.1 1.8 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KFO96061.1 - 0.18 11.9 1.0 0.37 10.9 0.2 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain CENP-M PF11111.8 KFO96062.1 - 4.4e-52 175.8 0.3 5e-52 175.6 0.3 1.0 1 0 0 1 1 1 1 Centromere protein M (CENP-M) Pox_I5 PF04713.12 KFO96062.1 - 0.081 13.0 0.2 0.13 12.4 0.2 1.4 1 0 0 1 1 1 0 Poxvirus protein I5 BaffR-Tall_bind PF09256.10 KFO96063.1 - 4.8e-08 32.6 4.1 1e-07 31.6 4.1 1.6 1 0 0 1 1 1 1 BAFF-R, TALL-1 binding COX16 PF14138.6 KFO96063.1 - 0.12 12.9 0.0 0.2 12.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 LapA_dom PF06305.11 KFO96063.1 - 0.14 12.0 0.1 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Shisa PF13908.6 KFO96064.1 - 2.2e-40 138.9 3.3 2.4e-40 138.8 3.3 1.0 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator HLH PF00010.26 KFO96065.1 - 3.3e-17 62.2 0.6 8.5e-17 60.9 0.6 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain AF-4 PF05110.13 KFO96065.1 - 0.043 11.9 6.8 0.065 11.3 6.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein ERK-JNK_inhib PF15002.6 KFO96066.1 - 1.9e-67 226.8 0.1 2.1e-67 226.6 0.1 1.0 1 0 0 1 1 1 1 ERK and JNK pathways, inhibitor TisB_toxin PF13939.6 KFO96067.1 - 3.5 7.5 8.4 14 5.6 0.5 3.7 3 0 0 3 3 3 0 Toxin TisB, type I toxin-antitoxin system Ribosomal_L7Ae PF01248.26 KFO96068.1 - 5.3e-26 90.2 0.1 6.6e-26 89.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KFO96068.1 - 0.00031 20.8 0.1 0.00035 20.6 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KFO96068.1 - 0.0069 16.2 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 PELOTA RNA binding domain Ku_N PF03731.15 KFO96069.1 - 1.6e-71 240.5 0.1 3e-71 239.7 0.1 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.16 KFO96069.1 - 3.7e-57 193.3 0.5 6e-57 192.7 0.5 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.14 KFO96069.1 - 1.3e-19 70.7 0.2 4.2e-19 69.0 0.2 2.0 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 KFO96069.1 - 3.2e-11 42.7 0.1 6.5e-11 41.7 0.1 1.6 1 0 0 1 1 1 1 SAP domain Peptidase_C97 PF05903.14 KFO96070.1 - 1.8e-36 125.3 0.0 2e-36 125.1 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain PMM PF03332.13 KFO96071.1 - 2.8e-110 367.3 0.1 3.2e-110 367.1 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase CSD PF00313.22 KFO96072.1 - 1e-13 50.9 0.1 1.3e-13 50.5 0.1 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KFO96072.1 - 0.0013 18.4 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease B OB domain RNA_pol_Rbc25 PF08292.12 KFO96073.1 - 6.4e-44 149.3 0.1 9.8e-44 148.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KFO96073.1 - 4.3e-20 71.9 0.1 9.1e-20 70.8 0.0 1.6 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Aconitase PF00330.20 KFO96074.1 - 6.7e-148 493.5 0.0 8.3e-148 493.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KFO96074.1 - 4.7e-46 156.3 0.0 9.1e-46 155.4 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain PHF5 PF03660.14 KFO96075.1 - 2.1e-39 133.9 14.1 2.3e-39 133.8 14.1 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 KFO96075.1 - 0.087 10.7 7.8 0.088 10.7 7.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 BTG PF07742.12 KFO96076.1 - 1.1e-37 128.4 0.0 1.6e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 BTG family PAM2 PF07145.15 KFO96076.1 - 6.8e-13 47.3 3.1 6.4e-06 25.5 0.0 3.7 4 0 0 4 4 4 2 Ataxin-2 C-terminal region MBD_C PF14048.6 KFO96076.1 - 0.084 13.6 0.4 0.21 12.3 0.1 1.8 2 0 0 2 2 2 0 C-terminal domain of methyl-CpG binding protein 2 and 3 bZIP_2 PF07716.15 KFO96077.1 - 9.6e-16 57.6 11.9 9.6e-16 57.6 11.9 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KFO96077.1 - 3.2e-06 27.1 7.9 6.1e-06 26.2 7.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor Cnn_1N PF07989.11 KFO96077.1 - 0.011 15.9 0.5 0.026 14.7 0.5 1.7 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 bZIP_Maf PF03131.17 KFO96077.1 - 0.037 14.5 5.4 0.087 13.3 5.4 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor COesterase PF00135.28 KFO96078.1 - 1.8e-125 419.8 0.0 2.2e-125 419.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Sarcoglycan_2 PF05510.13 KFO96078.1 - 0.015 14.1 0.0 0.032 13.0 0.0 1.5 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon Abhydrolase_3 PF07859.13 KFO96078.1 - 0.02 14.8 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold RVT_1 PF00078.27 KFO96079.1 - 0.074 12.6 0.0 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_M28 PF04389.17 KFO96081.1 - 2.4e-08 33.9 0.0 1e-07 31.9 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 TFR_dimer PF04253.15 KFO96081.1 - 2.5e-05 24.4 0.0 4.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain WD40 PF00400.32 KFO96082.1 - 8.6e-53 175.1 25.4 3.4e-10 40.3 0.2 8.5 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO96082.1 - 4.2e-29 100.7 2.1 6.9e-08 32.7 0.1 6.3 3 2 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFO96082.1 - 1.5e-11 44.5 0.5 0.001 19.0 0.1 3.4 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 KFO96082.1 - 6e-10 38.7 0.1 3.7e-09 36.2 0.0 2.2 2 0 0 2 2 2 1 LisH WD40_like PF17005.5 KFO96082.1 - 4.1e-05 23.1 0.0 0.08 12.3 0.0 3.1 4 1 0 4 4 4 2 WD40-like domain Coatomer_WDAD PF04053.14 KFO96082.1 - 0.00013 21.2 0.0 0.0047 16.0 0.0 2.4 2 0 0 2 2 2 1 Coatomer WD associated region Ge1_WD40 PF16529.5 KFO96082.1 - 0.00014 20.9 1.3 0.77 8.6 0.0 3.4 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFO96082.1 - 0.0067 15.1 4.7 0.68 8.5 0.0 3.8 2 2 2 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.12 KFO96082.1 - 0.032 14.2 0.0 0.49 10.4 0.0 3.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Glyco_hydro_11 PF00457.17 KFO96082.1 - 0.051 13.2 1.2 1.7 8.2 0.1 2.7 2 0 0 2 2 2 0 Glycosyl hydrolases family 11 PCuAC PF04314.13 KFO96082.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Copper chaperone PCu(A)C IKI3 PF04762.12 KFO96082.1 - 0.2 9.6 0.2 4.9 5.0 0.0 2.5 2 1 1 3 3 3 0 IKI3 family CaKB PF03185.15 KFO96083.1 - 4.1e-84 281.1 9.0 4.7e-84 280.9 9.0 1.0 1 0 0 1 1 1 1 Calcium-activated potassium channel, beta subunit KcnmB2_inactiv PF09303.10 KFO96083.1 - 3e-06 26.9 2.0 3e-06 26.9 2.0 1.6 2 0 0 2 2 2 1 KCNMB2, ball and chain domain AAA_8 PF12780.7 KFO96083.1 - 0.0029 17.0 0.0 0.0037 16.6 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 tRNA-synt_1g PF09334.11 KFO96083.1 - 0.0092 14.8 0.0 0.013 14.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) zf-met PF12874.7 KFO96084.1 - 1.9e-22 78.9 16.9 1.4e-08 34.8 0.4 3.4 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFO96084.1 - 9.2e-20 70.4 16.7 9.2e-07 29.0 0.2 3.3 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFO96084.1 - 3.5e-09 36.9 11.7 0.016 15.5 0.5 3.2 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFO96084.1 - 0.00034 21.2 5.8 2.5 9.2 0.1 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-U1 PF06220.12 KFO96084.1 - 0.00088 19.0 18.3 0.1 12.4 3.0 3.6 3 1 0 3 3 3 2 U1 zinc finger AKAP95 PF04988.12 KFO96084.1 - 0.01 16.1 0.7 0.01 16.1 0.7 3.0 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.26 KFO96084.1 - 4.3 8.0 8.7 6.2 7.5 0.1 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2 PF00096.26 KFO96085.1 - 4.4e-17 61.5 60.0 0.0025 18.2 1.0 9.7 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO96085.1 - 2.8e-14 52.6 60.7 0.0051 17.6 1.3 9.8 9 0 0 9 9 9 5 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFO96085.1 - 1.6e-11 43.7 43.8 3.6e-05 23.4 3.0 7.7 8 0 0 8 8 8 3 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KFO96085.1 - 3.7e-11 42.9 53.4 0.00017 21.8 0.2 9.7 9 0 0 9 9 9 6 Zinc-finger double domain zf-C2H2_6 PF13912.6 KFO96085.1 - 0.0017 18.3 1.3 0.0017 18.3 1.3 8.5 8 1 0 8 8 8 1 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KFO96085.1 - 0.0031 17.1 45.3 0.021 14.5 0.2 6.9 5 3 1 6 6 6 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 KFO96085.1 - 0.061 13.7 1.0 0.061 13.7 1.0 7.6 8 0 0 8 8 8 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFO96085.1 - 0.1 12.9 30.6 0.14 12.4 2.2 5.1 1 1 3 5 5 5 0 C2H2-type zinc ribbon zinc_ribbon_15 PF17032.5 KFO96085.1 - 0.17 12.6 33.9 0.19 12.5 3.4 5.1 3 1 1 5 5 5 0 zinc-ribbon family CarbpepA_inh PF02977.15 KFO96085.1 - 1.8 8.5 15.2 1.9 8.4 0.0 5.1 5 0 0 5 5 5 0 Carboxypeptidase A inhibitor zf-C2H2_2 PF12756.7 KFO96085.1 - 2.5 8.5 50.3 7.7 6.9 13.9 5.9 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) Fzo_mitofusin PF04799.13 KFO96086.1 - 8.8e-73 243.2 6.5 8.8e-73 243.2 6.5 3.4 2 1 2 4 4 4 1 fzo-like conserved region Dynamin_N PF00350.23 KFO96086.1 - 1.9e-23 83.3 0.0 1.9e-23 83.3 0.0 3.7 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 KFO96086.1 - 4.9e-08 33.0 0.1 3.6e-07 30.3 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Apolipoprotein PF01442.18 KFO96086.1 - 0.023 14.6 9.2 0.068 13.0 0.4 2.7 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Roc PF08477.13 KFO96086.1 - 0.071 13.3 0.2 14 6.0 0.0 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Phospholip_A2_3 PF09056.11 KFO96086.1 - 0.39 11.4 2.3 1.7 9.3 0.1 3.0 3 0 0 3 3 3 0 Prokaryotic phospholipase A2 CorA PF01544.18 KFO96086.1 - 0.43 9.9 9.6 0.2 11.0 1.4 2.9 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein CLZ PF16526.5 KFO96086.1 - 0.75 10.2 9.9 2.6 8.5 0.2 3.8 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Tup_N PF08581.10 KFO96086.1 - 2.6 8.4 12.6 4.5 7.6 0.3 3.9 3 1 0 3 3 3 0 Tup N-terminal FadA PF09403.10 KFO96086.1 - 5.4 7.6 13.0 0.65 10.5 1.3 3.6 3 2 0 3 3 3 0 Adhesion protein FadA AAA_23 PF13476.6 KFO96086.1 - 7.1 7.1 0.0 7.1 7.1 0.0 3.6 3 1 0 3 3 3 0 AAA domain GrpE PF01025.19 KFO96086.1 - 8.8 6.0 15.1 7.7 6.1 3.6 2.9 2 1 0 2 2 2 0 GrpE WD40 PF00400.32 KFO96087.1 - 1.9e-44 148.8 21.3 4.1e-08 33.8 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO96087.1 - 1.7e-16 60.2 0.0 0.00086 19.6 0.0 5.7 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFO96087.1 - 6.8e-05 22.8 0.0 0.42 10.5 0.0 2.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KFO96087.1 - 9.4e-05 21.9 0.0 0.02 14.2 0.0 2.9 1 1 1 2 2 2 2 WD40-like domain Actin PF00022.19 KFO96088.1 - 7.6e-116 387.1 0.0 1.5e-98 330.1 0.0 2.0 2 0 0 2 2 2 2 Actin MobA_MobL PF03389.15 KFO96088.1 - 0.19 11.5 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 MobA/MobL family MRP-L47 PF06984.13 KFO96089.1 - 4.2e-35 119.7 1.1 4.2e-35 119.7 1.1 1.9 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) NDUF_B5 PF09781.9 KFO96090.1 - 2.8e-81 271.6 0.5 3.1e-81 271.5 0.5 1.0 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit TPR_1 PF00515.28 KFO96091.1 - 1.5e-25 87.9 1.7 2e-05 24.2 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFO96091.1 - 1.5e-21 74.7 6.3 0.00021 21.2 0.0 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KFO96091.1 - 3.9e-19 67.2 0.3 0.0024 18.0 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFO96091.1 - 4.3e-15 55.1 1.5 0.0021 17.7 0.0 5.5 3 2 2 5 5 5 3 TPR repeat TPR_14 PF13428.6 KFO96091.1 - 2.2e-14 52.9 6.3 0.0037 18.0 0.7 6.2 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_19 PF14559.6 KFO96091.1 - 2.9e-14 53.3 5.9 0.00093 19.7 2.3 4.6 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFO96091.1 - 1.3e-13 50.3 9.3 0.0052 17.1 0.5 5.6 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFO96091.1 - 5.9e-11 42.8 6.8 6.7e-06 26.7 0.4 4.3 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_9 PF13371.6 KFO96091.1 - 1.1e-10 41.4 4.5 0.00026 21.1 0.4 4.2 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_20 PF14561.6 KFO96091.1 - 1.2e-08 35.1 4.1 0.00022 21.5 0.7 4.3 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFO96091.1 - 2.4e-08 34.2 6.5 0.55 10.6 0.0 4.6 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFO96091.1 - 2.5e-08 33.4 1.6 2.2 8.5 0.1 5.7 4 1 1 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO96091.1 - 6.8e-08 32.6 2.1 0.0014 18.8 1.7 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KFO96091.1 - 5.6e-07 29.8 5.1 6.3 7.7 0.2 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 KFO96091.1 - 0.0015 17.9 5.1 2.1 7.8 0.1 3.6 3 0 0 3 3 3 1 SHNi-TPR TPR_3 PF07720.12 KFO96091.1 - 0.0052 16.8 0.0 5 7.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFO96091.1 - 0.008 15.4 4.2 0.065 12.4 0.8 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4248 PF14053.6 KFO96091.1 - 0.012 15.7 0.2 0.034 14.2 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) DUF4919 PF16266.5 KFO96091.1 - 0.072 13.0 0.2 0.2 11.6 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) Wzy_C_2 PF11846.8 KFO96091.1 - 0.093 12.6 0.6 0.24 11.3 0.6 1.7 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal BTAD PF03704.17 KFO96091.1 - 0.095 13.1 4.1 8 6.9 0.1 3.1 3 0 0 3 3 2 0 Bacterial transcriptional activator domain DUF4192 PF13830.6 KFO96091.1 - 0.77 9.8 4.3 0.95 9.5 0.1 3.0 3 1 1 4 4 3 0 Domain of unknown function (DUF4192) TPR_1 PF00515.28 KFO96092.1 - 1.5e-13 49.9 0.3 0.00071 19.3 0.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFO96092.1 - 3.2e-12 45.6 5.0 0.0005 20.0 0.0 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFO96092.1 - 1.8e-10 40.3 1.1 6.1e-09 35.4 0.1 3.0 2 1 0 2 2 2 1 TPR repeat TPR_14 PF13428.6 KFO96092.1 - 7.3e-08 32.6 0.1 0.038 14.8 0.0 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFO96092.1 - 9.2e-08 31.7 0.3 0.065 13.5 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFO96092.1 - 3.5e-06 27.6 0.2 1.6e-05 25.4 0.0 2.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFO96092.1 - 9.1e-06 25.7 0.0 2.8e-05 24.2 0.0 1.8 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFO96092.1 - 1.4e-05 25.2 0.9 0.00035 20.7 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFO96092.1 - 0.00063 20.0 1.8 0.82 10.0 0.5 3.3 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFO96092.1 - 0.0011 19.4 4.7 0.022 15.3 0.1 3.9 2 1 3 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFO96092.1 - 0.0022 17.3 2.3 0.0047 16.2 2.3 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat S1 PF00575.23 KFO96092.1 - 0.0052 17.1 0.0 0.054 13.8 0.0 2.4 1 1 0 1 1 1 1 S1 RNA binding domain HCNGP PF07818.13 KFO96092.1 - 0.0072 17.0 2.5 0.019 15.6 0.0 2.6 2 0 0 2 2 2 1 HCNGP-like protein TPR_10 PF13374.6 KFO96092.1 - 0.17 11.8 0.4 6.3 6.8 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Mem_trans PF03547.18 KFO96092.1 - 8.9 4.6 8.4 17 3.6 8.4 1.5 1 0 0 1 1 1 0 Membrane transport protein KELK PF15796.5 KFO96093.1 - 0.0082 16.6 7.5 0.0082 16.6 7.5 12.7 3 3 5 12 12 12 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase CENP-F_leu_zip PF10473.9 KFO96093.1 - 0.0084 16.1 22.7 0.0084 16.1 22.7 9.3 1 1 7 9 9 9 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ABC_tran_CTD PF16326.5 KFO96093.1 - 0.015 15.6 0.4 0.015 15.6 0.4 11.9 5 3 5 11 11 11 0 ABC transporter C-terminal domain Chal_sti_synt_N PF00195.19 KFO96093.1 - 2.2 7.7 5.2 9.1 5.6 1.3 3.4 2 1 1 3 3 3 0 Chalcone and stilbene synthases, N-terminal domain FXMRP1_C_core PF12235.8 KFO96094.1 - 1.2e-46 158.8 11.7 1.2e-46 158.8 11.7 3.6 1 1 2 3 3 3 1 Fragile X-related 1 protein core C terminal FXR_C1 PF16096.5 KFO96094.1 - 1.2e-38 131.2 12.0 1.2e-38 131.2 12.0 3.5 2 1 1 3 3 3 1 Fragile X-related 1 protein C-terminal region 2 KH_9 PF17904.1 KFO96094.1 - 8.8e-36 122.2 0.7 2.5e-35 120.7 0.7 1.8 1 0 0 1 1 1 1 FMRP KH0 domain FXR_C3 PF16097.5 KFO96094.1 - 6e-27 94.1 7.1 6e-27 94.1 7.1 3.0 3 1 1 4 4 4 1 Fragile X-related 1 protein C-terminal region 3 Tudor_FRX1 PF18336.1 KFO96094.1 - 4.4e-19 68.1 1.6 4.4e-19 68.1 1.6 2.0 2 0 0 2 2 2 1 Fragile X mental retardation Tudor domain KH_1 PF00013.29 KFO96094.1 - 4.8e-17 61.5 1.0 1.6e-09 37.4 0.5 2.7 2 0 0 2 2 2 2 KH domain Agenet PF05641.12 KFO96094.1 - 2.1e-10 40.9 3.3 1.4e-08 35.1 0.2 3.0 3 0 0 3 3 3 1 Agenet domain KH_2 PF07650.17 KFO96094.1 - 0.00026 20.7 0.8 0.16 11.8 0.0 2.6 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 KFO96094.1 - 0.3 11.0 4.5 2.2 8.2 0.4 3.5 3 1 0 3 3 3 0 KH domain Peptidase_C101 PF16218.5 KFO96095.1 - 7.6e-109 363.1 0.9 9.8e-109 362.7 0.9 1.1 1 0 0 1 1 1 1 Peptidase family C101 Peptidase_C65 PF10275.9 KFO96095.1 - 0.021 14.2 1.4 2.1 7.7 0.0 2.8 3 1 1 4 4 4 0 Peptidase C65 Otubain ANKH PF07260.11 KFO96096.1 - 1.5e-200 665.5 4.3 1.5e-200 665.5 4.3 1.4 2 0 0 2 2 2 1 Progressive ankylosis protein (ANKH) UCR_Fe-S_N PF10399.9 KFO96096.1 - 0.83 9.0 0.0 0.83 9.0 0.0 2.7 3 0 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal SUI1 PF01253.22 KFO96097.1 - 7.4e-15 55.3 0.5 8.5e-15 55.1 0.5 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 LRR_6 PF13516.6 KFO96098.1 - 1.6e-30 102.6 2.3 0.015 15.3 0.0 10.8 11 0 0 11 11 11 9 Leucine Rich repeat F-box-like PF12937.7 KFO96098.1 - 5.3e-17 61.4 4.9 1.5e-16 60.0 4.9 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KFO96098.1 - 1.4e-16 60.3 0.0 0.013 15.9 0.0 6.6 3 2 4 7 7 7 6 Leucine Rich repeats (2 copies) F-box PF00646.33 KFO96098.1 - 2.8e-12 46.2 2.2 2.8e-12 46.2 2.2 2.7 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.33 KFO96098.1 - 4.7e-12 44.7 6.2 2.9 8.8 0.0 10.1 10 1 0 10 10 10 2 Leucine Rich Repeat RINGv PF12906.7 KFO96099.1 - 9.9e-13 48.0 8.0 2.4e-12 46.8 8.0 1.7 1 0 0 1 1 1 1 RING-variant domain DUF3262 PF11660.8 KFO96099.1 - 0.028 14.8 3.1 0.17 12.3 2.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3262) ABC_cobalt PF09819.9 KFO96099.1 - 0.036 14.2 2.3 0.056 13.6 2.3 1.2 1 0 0 1 1 1 0 ABC-type cobalt transport system, permease component zf-C3HC4 PF00097.25 KFO96099.1 - 0.054 13.4 2.3 0.48 10.3 2.3 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2_jaz PF12171.8 KFO96100.1 - 3.3e-12 46.4 8.2 3.9e-07 30.2 3.8 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFO96100.1 - 6e-06 26.5 8.4 0.00012 22.4 0.9 3.2 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFO96100.1 - 4.2e-05 23.8 3.4 4.2e-05 23.8 3.4 3.3 4 0 0 4 4 4 1 Zinc-finger of C2H2 type DUF629 PF04780.12 KFO96100.1 - 0.0025 16.4 4.2 0.037 12.6 0.8 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.6 KFO96100.1 - 0.0044 17.7 7.4 0.0073 17.1 0.8 3.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFO96100.1 - 0.0078 16.2 1.7 0.0078 16.2 1.7 2.8 3 0 0 3 3 3 1 C2H2-type zinc finger TENA_THI-4 PF03070.16 KFO96100.1 - 0.032 14.1 0.3 0.057 13.2 0.2 1.4 1 1 0 1 1 1 0 TENA/THI-4/PQQC family zf-DBF PF07535.12 KFO96100.1 - 0.05 13.7 0.9 0.05 13.7 0.9 2.9 3 0 0 3 3 3 0 DBF zinc finger zf-C2H2 PF00096.26 KFO96100.1 - 0.37 11.3 6.9 0.19 12.2 2.0 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-LYAR PF08790.11 KFO96100.1 - 0.43 10.5 8.4 2.1 8.3 0.1 2.7 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger DUF4401 PF14351.6 KFO96101.1 - 0.07 12.4 1.0 0.1 11.9 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) Reticulon PF02453.17 KFO96101.1 - 0.28 11.2 6.8 1 9.3 5.5 2.4 2 1 0 2 2 2 0 Reticulon LamB_YcsF PF03746.16 KFO96102.1 - 0.2 11.3 0.0 0.21 11.2 0.0 1.0 1 0 0 1 1 1 0 LamB/YcsF family BASP1 PF05466.12 KFO96103.1 - 9.5e-96 320.4 95.0 1.1e-95 320.2 95.0 1.0 1 0 0 1 1 1 1 Brain acid soluble protein 1 (BASP1 protein) PNPase_C PF12111.8 KFO96104.1 - 0.21 11.1 0.4 0.47 9.9 0.4 1.5 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal Yae1_N PF09811.9 KFO96105.1 - 2e-11 43.4 32.9 0.00019 21.1 5.9 3.2 2 1 0 2 2 2 2 Essential protein Yae1, N terminal Cadherin PF00028.17 KFO96106.1 - 1.1e-83 275.8 7.4 8.7e-19 67.8 0.2 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFO96106.1 - 9.1e-55 185.0 1.9 1.7e-54 184.1 0.9 2.0 2 0 0 2 2 2 1 Cadherin cytoplasmic region Cadherin_3 PF16184.5 KFO96106.1 - 1.5e-11 44.3 3.5 0.0051 16.8 0.0 5.1 5 0 0 5 5 5 3 Cadherin-like Cadherin_2 PF08266.12 KFO96106.1 - 0.00018 21.3 0.0 3.8 7.4 0.0 4.4 4 0 0 4 4 4 1 Cadherin-like Cadherin_4 PF17803.1 KFO96106.1 - 0.039 14.6 0.8 0.039 14.6 0.8 4.4 4 0 0 4 4 4 0 Bacterial cadherin-like domain ASFV_J13L PF05568.11 KFO96106.1 - 0.076 12.8 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Invasin_D3 PF09134.10 KFO96106.1 - 0.18 12.1 9.3 14 6.0 0.0 4.7 4 1 1 5 5 5 0 Invasin, domain 3 CTD PF12815.7 KFO96108.1 - 9.7e-05 22.9 31.7 2 9.1 6.5 4.6 1 1 1 2 2 2 1 Spt5 C-terminal nonapeptide repeat binding Spt4 fn3 PF00041.21 KFO96109.1 - 0.029 14.7 0.2 0.1 13.0 0.2 1.7 1 1 0 1 1 1 0 Fibronectin type III domain fn3 PF00041.21 KFO96110.1 - 1.1e-184 599.3 56.6 9.7e-13 48.3 0.2 20.5 20 0 0 20 20 20 19 Fibronectin type III domain Y_phosphatase PF00102.27 KFO96110.1 - 4e-75 252.4 0.0 8.1e-75 251.4 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Pur_ac_phosph_N PF16656.5 KFO96110.1 - 4.5e-23 81.6 54.0 0.0093 16.5 0.0 17.4 16 5 0 16 16 16 7 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFO96110.1 - 7.2e-09 35.9 3.2 15 5.9 0.0 11.2 14 0 0 14 14 14 1 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 KFO96110.1 - 0.00062 20.1 1.0 14 6.2 0.0 6.4 8 0 0 8 8 8 1 Uncharacterised conserved protein (DUF2369) Y_phosphatase3 PF13350.6 KFO96110.1 - 0.00068 19.7 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF4959 PF16323.5 KFO96110.1 - 0.0012 19.1 6.5 0.32 11.3 0.2 6.4 6 1 0 6 6 6 1 Domain of unknown function (DUF4959) DSPc PF00782.20 KFO96110.1 - 0.038 13.8 0.0 0.13 12.0 0.0 1.9 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFO96110.1 - 0.055 13.6 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 Inositol hexakisphosphate CBM_4_9 PF02018.17 KFO96110.1 - 6.3 7.1 13.2 17 5.6 0.0 6.6 9 0 0 9 9 9 0 Carbohydrate binding domain PDZ PF00595.24 KFO96111.1 - 7.4e-21 74.3 0.4 1.2e-20 73.6 0.4 1.3 1 0 0 1 1 1 1 PDZ domain L27 PF02828.16 KFO96111.1 - 1.1e-14 53.9 0.1 2.6e-14 52.7 0.0 1.7 2 0 0 2 2 2 1 L27 domain PDZ_6 PF17820.1 KFO96111.1 - 1.1e-13 50.8 0.3 3.4e-13 49.2 0.1 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KFO96111.1 - 0.00068 19.9 0.1 0.0015 18.8 0.0 1.6 2 0 0 2 2 2 1 PDZ domain EAP30 PF04157.16 KFO96111.1 - 0.021 14.1 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family AMP-binding PF00501.28 KFO96112.1 - 3e-71 240.3 0.0 3.8e-71 239.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFO96112.1 - 1.1e-18 68.0 0.5 3.4e-18 66.4 0.5 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KFO96112.1 - 4.5e-17 61.7 0.1 1.5e-16 60.1 0.1 2.0 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus rRNA_processing PF08524.11 KFO96115.1 - 3.5e-11 43.3 39.9 2.3e-10 40.7 39.9 1.9 1 1 0 1 1 1 1 rRNA processing DUF4554 PF15091.6 KFO96115.1 - 0.45 9.4 8.2 0.48 9.2 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) CDC45 PF02724.14 KFO96115.1 - 0.86 7.8 13.0 0.86 7.8 13.0 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4407 PF14362.6 KFO96115.1 - 2.8 7.2 14.4 3.6 6.9 14.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OrfB_IS605 PF01385.19 KFO96115.1 - 5.1 7.4 16.2 3.2 8.0 9.1 2.3 2 0 0 2 2 2 0 Probable transposase Methyltransf_32 PF13679.6 KFO96116.1 - 4.3e-31 108.1 7.8 1.4e-29 103.1 7.8 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFO96116.1 - 0.0016 18.3 0.0 0.0065 16.3 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFO96116.1 - 0.0034 18.1 0.0 0.013 16.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFO96116.1 - 0.0052 16.6 0.0 0.032 14.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 KFO96116.1 - 0.068 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 KFO96116.1 - 0.092 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain MetW PF07021.12 KFO96116.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DUF1736 PF08409.11 KFO96117.1 - 3.8e-30 103.7 1.5 3.8e-30 103.7 1.5 2.0 2 0 0 2 2 1 1 Domain of unknown function (DUF1736) TPR_1 PF00515.28 KFO96117.1 - 4e-25 86.6 6.0 4.2e-05 23.2 0.2 5.5 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 KFO96117.1 - 3.1e-20 70.6 6.1 0.00021 21.1 0.2 5.5 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.6 KFO96117.1 - 3.5e-16 59.3 6.4 3.1e-07 30.6 0.1 4.0 3 2 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFO96117.1 - 4e-16 57.8 10.3 0.016 15.4 0.4 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 KFO96117.1 - 7.5e-13 47.9 12.3 0.0027 17.5 0.0 5.7 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFO96117.1 - 7.6e-13 47.5 4.1 0.0032 17.4 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFO96117.1 - 2e-12 46.5 4.8 0.00041 20.0 0.3 4.3 3 2 2 5 5 5 3 TPR repeat TPR_16 PF13432.6 KFO96117.1 - 6.9e-12 45.8 0.1 0.0006 20.4 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFO96117.1 - 2.8e-06 27.6 3.1 0.024 15.2 0.1 4.2 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFO96117.1 - 1.5e-05 25.4 1.4 0.018 15.6 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFO96117.1 - 4e-05 23.1 0.2 0.0015 18.0 0.0 2.1 1 1 1 2 2 2 1 MalT-like TPR region TPR_17 PF13431.6 KFO96117.1 - 6.3e-05 23.1 11.2 2.5 8.7 0.1 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO96117.1 - 0.00014 22.0 7.4 0.079 13.2 1.5 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KFO96117.1 - 0.00016 22.2 0.4 1 10.3 0.0 4.9 3 2 2 5 5 5 1 Tetratricopeptide repeat PMT_2 PF13231.6 KFO96117.1 - 0.002 18.3 4.8 0.002 18.3 4.8 2.4 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase TPR_3 PF07720.12 KFO96117.1 - 0.0063 16.5 8.1 0.4 10.7 0.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.9 KFO96117.1 - 0.0084 15.8 0.1 4.7 6.9 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat-like domain DUF389 PF04087.14 KFO96117.1 - 0.016 15.2 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF389) TPR_9 PF13371.6 KFO96117.1 - 0.018 15.1 0.3 2.4 8.4 0.0 3.0 2 1 2 4 4 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 KFO96117.1 - 0.032 13.5 2.1 12 5.0 0.1 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat RPN7 PF10602.9 KFO96117.1 - 0.06 13.0 0.8 1.5 8.5 0.2 2.9 1 1 1 2 2 2 0 26S proteasome subunit RPN7 DUF2225 PF09986.9 KFO96117.1 - 0.096 12.4 1.5 0.32 10.7 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) PMT PF02366.18 KFO96117.1 - 0.17 11.4 14.8 0.0098 15.5 9.0 1.9 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase TPR_4 PF07721.14 KFO96117.1 - 0.22 12.3 0.2 1.3 9.8 0.0 2.5 3 0 0 3 3 1 0 Tetratricopeptide repeat MIT PF04212.18 KFO96117.1 - 1.8 8.7 5.4 10 6.3 0.1 3.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain zf_CCCH_4 PF18345.1 KFO96118.1 - 1.2e-16 60.1 24.1 4.8e-06 26.5 5.7 3.4 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH PF00642.24 KFO96118.1 - 2.2e-13 49.8 16.8 0.00012 21.8 0.9 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KFO96118.1 - 3.4e-12 45.9 19.1 1.2e-09 37.7 2.6 3.4 3 0 0 3 3 3 3 CCCH-type zinc finger Torus PF16131.5 KFO96118.1 - 0.00025 21.7 0.7 0.00025 21.7 0.7 4.6 3 1 2 5 5 5 3 Torus domain zf-CCCH_2 PF14608.6 KFO96118.1 - 0.02 15.4 22.3 1.7 9.2 1.6 3.5 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KFO96118.1 - 0.025 14.8 9.3 0.13 12.4 1.3 2.4 1 1 1 2 2 2 0 Zinc-finger containing family DUF3678 PF12435.8 KFO96118.1 - 1.3 8.5 3.6 3.4 7.1 3.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) Baculo_PP31 PF05311.11 KFO96118.1 - 2.1 7.7 11.7 4.7 6.6 11.7 1.5 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) ThiF PF00899.21 KFO96119.1 - 0.033 13.5 0.0 0.033 13.5 0.0 1.1 1 0 0 1 1 1 0 ThiF family OB_NTP_bind PF07717.16 KFO96120.1 - 7.8e-14 51.8 0.0 2.4e-13 50.3 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFO96120.1 - 1.1e-11 45.1 0.0 6.2e-11 42.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.23 KFO96120.1 - 0.00052 20.3 0.0 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 KFO96120.1 - 0.0007 19.4 0.0 0.043 13.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFO96120.1 - 0.022 15.0 0.1 0.19 12.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KFO96120.1 - 0.09 12.7 0.0 0.43 10.5 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain V-set PF07686.17 KFO96121.1 - 2e-16 60.1 1.0 2.5e-13 50.1 0.0 3.2 3 0 0 3 3 3 1 Immunoglobulin V-set domain I-set PF07679.16 KFO96121.1 - 2.3e-13 50.0 0.5 1.3e-06 28.4 0.0 3.1 2 2 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO96121.1 - 6.4e-13 49.1 1.4 2.3e-05 24.9 0.1 3.1 3 1 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KFO96121.1 - 1.5e-11 44.4 0.7 6.4e-08 32.8 0.2 2.8 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFO96121.1 - 2.4e-11 43.7 0.2 6.2e-06 26.3 0.0 3.1 2 2 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 KFO96121.1 - 0.00018 21.0 0.2 0.056 13.0 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFO96121.1 - 0.00041 20.3 0.1 0.012 15.6 0.1 2.5 2 0 0 2 2 2 1 C17orf99 Ig domain FAM176 PF14851.6 KFO96121.1 - 0.0051 16.5 0.1 0.068 12.8 0.1 2.1 2 0 0 2 2 2 1 FAM176 family SMN PF06003.12 KFO96121.1 - 0.0069 15.7 1.4 0.012 14.9 1.4 1.3 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) OSTbeta PF15048.6 KFO96121.1 - 0.011 15.8 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein TMEM51 PF15345.6 KFO96121.1 - 0.017 14.9 1.3 0.046 13.6 1.3 1.6 1 1 0 1 1 1 0 Transmembrane protein 51 Miga PF10265.9 KFO96121.1 - 0.025 13.6 0.9 0.032 13.2 0.9 1.2 1 0 0 1 1 1 0 Mitoguardin Syndecan PF01034.20 KFO96121.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 KFO96121.1 - 0.15 13.0 0.0 0.31 11.9 0.0 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Izumo-Ig PF16706.5 KFO96121.1 - 0.15 12.2 0.3 2.3 8.3 0.0 2.5 2 1 0 2 2 2 0 Izumo-like Immunoglobulin domain DUF5305 PF17231.2 KFO96121.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Herpes_pp85 PF04637.12 KFO96121.1 - 1.1 7.6 3.1 1.5 7.2 3.1 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF3446 PF11928.8 KFO96121.1 - 5 7.5 12.5 15 6.0 12.5 1.7 1 0 0 1 1 1 0 Early growth response N-terminal domain HSP70 PF00012.20 KFO96122.1 - 6.4e-265 880.0 12.3 7.2e-265 879.8 12.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFO96122.1 - 1.4e-18 66.8 0.5 3.9e-17 62.1 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KFO96122.1 - 0.0014 19.0 4.3 1.5 9.3 0.1 3.6 3 2 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 KFO96122.1 - 0.0018 18.1 0.0 0.0049 16.6 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 KFO96122.1 - 0.012 15.2 0.1 4.8 6.6 0.0 2.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DDR PF08841.10 KFO96122.1 - 0.033 13.2 0.3 0.18 10.8 0.3 2.0 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain HORMA PF02301.18 KFO96122.1 - 0.079 12.5 1.2 0.2 11.2 1.2 1.6 1 0 0 1 1 1 0 HORMA domain MetOD2 PF18548.1 KFO96122.1 - 0.31 11.2 0.1 0.31 11.2 0.1 3.0 2 1 1 3 3 3 0 Metanogen output domain 2 Homeodomain PF00046.29 KFO96123.1 - 2.8e-22 78.3 1.9 4.2e-22 77.7 1.9 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO96123.1 - 0.043 13.7 0.0 0.043 13.7 0.0 2.6 2 0 0 2 2 2 0 Homeobox KN domain C2-set_2 PF08205.12 KFO96124.1 - 5.9e-09 35.9 0.2 1.1e-08 35.0 0.2 1.4 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain I-set PF07679.16 KFO96124.1 - 5.9e-08 32.7 0.0 0.0014 18.7 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO96124.1 - 1e-06 29.2 2.4 0.0044 17.6 0.3 2.7 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 KFO96124.1 - 5.1e-05 23.4 0.2 0.0025 18.0 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin V-set domain C1-set PF07654.15 KFO96124.1 - 7.2e-05 23.1 1.0 0.00025 21.4 0.1 2.1 2 0 0 2 2 2 1 Immunoglobulin C1-set domain ig PF00047.25 KFO96124.1 - 0.00056 20.0 3.0 1 9.6 0.2 3.2 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KFO96124.1 - 0.0052 17.1 0.4 1.5 9.3 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin domain DUF3169 PF11368.8 KFO96124.1 - 0.017 14.7 0.0 0.024 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF4630 PF15443.6 KFO96124.1 - 0.028 14.6 0.1 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4630) SH3_9 PF14604.6 KFO96125.1 - 1e-17 63.7 0.0 2.1e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain His_Phos_1 PF00300.22 KFO96125.1 - 4e-17 62.6 0.0 1.5e-16 60.7 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 2_5_RNA_ligase2 PF13563.6 KFO96125.1 - 3.4e-06 27.0 0.9 9e-06 25.7 0.4 1.9 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily SH3_1 PF00018.28 KFO96125.1 - 4.6e-05 22.9 0.0 9.4e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain LigT_PEase PF02834.16 KFO96125.1 - 5.7e-05 23.2 0.1 0.36 11.0 0.1 2.7 2 0 0 2 2 2 2 LigT like Phosphoesterase Sortilin-Vps10 PF15902.5 KFO96126.1 - 8.3e-114 380.8 0.0 1.7e-113 379.8 0.0 1.5 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Ldl_recept_a PF00057.18 KFO96126.1 - 1.2e-113 371.0 207.9 5.2e-14 52.2 7.7 12.2 12 0 0 12 12 12 11 Low-density lipoprotein receptor domain class A Sortilin_C PF15901.5 KFO96126.1 - 2.4e-40 138.7 0.1 2.4e-40 138.7 0.1 5.4 3 2 3 6 6 1 1 Sortilin, neurotensin receptor 3, C-terminal fn3 PF00041.21 KFO96126.1 - 9.5e-33 112.4 11.9 1e-08 35.4 0.0 6.4 6 0 0 6 6 6 5 Fibronectin type III domain Ldl_recept_b PF00058.17 KFO96126.1 - 1.2e-23 83.2 6.0 5.1e-08 33.3 0.1 5.7 5 0 0 5 5 5 5 Low-density lipoprotein receptor repeat class B Interfer-bind PF09294.10 KFO96126.1 - 1.4e-05 25.4 11.6 2.5 8.4 1.8 5.7 5 0 0 5 5 5 2 Interferon-alpha/beta receptor, fibronectin type III Pur_ac_phosph_N PF16656.5 KFO96126.1 - 4e-05 24.1 11.9 0.38 11.3 0.0 5.0 5 0 0 5 5 4 2 Purple acid Phosphatase, N-terminal domain BNR_6 PF15899.5 KFO96126.1 - 0.0001 22.0 3.3 0.51 10.5 0.8 3.5 2 0 0 2 2 2 2 BNR-Asp box repeat BNR PF02012.20 KFO96126.1 - 0.00065 19.3 15.1 2.1 8.7 0.2 5.8 5 0 0 5 5 5 1 BNR/Asp-box repeat fn3_2 PF16893.5 KFO96126.1 - 0.0079 16.3 4.0 1.5 9.0 0.0 4.3 5 1 1 6 6 6 1 Fibronectin type III domain CHB_HEX_C PF03174.13 KFO96126.1 - 0.11 12.5 0.4 8.8 6.4 0.0 2.7 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain DUF3377 PF11857.8 KFO96126.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) FA_hydroxylase PF04116.13 KFO96127.1 - 4.9e-25 88.4 22.3 4.2e-24 85.4 20.6 2.1 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily LRR_9 PF14580.6 KFO96128.1 - 9.1e-12 44.8 3.3 8.2e-09 35.2 0.1 3.2 2 1 1 3 3 3 2 Leucine-rich repeat LRR_4 PF12799.7 KFO96128.1 - 3.2e-08 33.7 27.6 0.0015 18.9 1.1 5.8 3 1 4 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFO96128.1 - 5.7e-07 29.2 17.6 0.005 16.6 2.6 4.3 1 1 4 5 5 5 5 Leucine rich repeat Ubiquitin_2 PF14560.6 KFO96128.1 - 1.7e-06 28.4 0.1 6.4e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-like domain ubiquitin PF00240.23 KFO96128.1 - 0.049 13.4 0.2 0.15 11.8 0.2 1.9 1 1 0 1 1 1 0 Ubiquitin family LRR_6 PF13516.6 KFO96128.1 - 0.069 13.2 17.1 1.5 9.0 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich repeat APG12 PF04110.13 KFO96128.1 - 0.077 13.4 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 ANF_receptor PF01094.28 KFO96129.1 - 9.7e-61 205.8 0.0 1.6e-60 205.1 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 KFO96129.1 - 3.6e-48 163.2 0.1 5.8e-48 162.5 0.1 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFO96129.1 - 1.1e-44 151.3 0.0 4.4e-44 149.3 0.0 2.0 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFO96129.1 - 2.8e-20 72.7 0.0 5.4e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.6 KFO96129.1 - 0.11 12.1 0.0 0.29 10.8 0.0 1.5 2 0 0 2 2 2 0 Periplasmic binding protein TRAM_LAG1_CLN8 PF03798.16 KFO96130.1 - 0.0041 16.9 0.2 0.0041 16.9 0.2 1.4 2 0 0 2 2 2 1 TLC domain Pou PF00157.17 KFO96132.1 - 2.9e-38 129.7 0.6 6.5e-38 128.6 0.2 1.8 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KFO96132.1 - 1.4e-18 66.4 3.3 3.9e-18 65.0 3.3 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO96132.1 - 0.07 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain HTH_3 PF01381.22 KFO96132.1 - 0.14 12.2 0.2 1.3 9.1 0.0 2.3 2 1 0 2 2 2 0 Helix-turn-helix OAF PF14941.6 KFO96133.1 - 8.4e-93 310.3 3.2 9.4e-93 310.1 3.2 1.0 1 0 0 1 1 1 1 Transcriptional regulator, Out at first C2-set_2 PF08205.12 KFO96134.1 - 2.8e-20 72.2 0.2 1.7e-18 66.5 0.1 2.5 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFO96134.1 - 3e-19 69.2 0.5 9e-16 58.0 0.0 3.4 3 1 0 3 3 3 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFO96134.1 - 3.2e-18 66.1 1.2 8.2e-08 32.7 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFO96134.1 - 2.3e-17 62.9 0.4 4.8e-07 29.9 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFO96134.1 - 9.1e-15 54.8 2.6 3.9e-07 30.3 0.1 3.8 3 1 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFO96134.1 - 4.9e-08 32.9 0.3 0.00082 19.4 0.0 3.5 3 1 0 3 3 3 2 Immunoglobulin I-set domain Ig_6 PF18452.1 KFO96134.1 - 0.0035 16.9 0.0 2.4 7.8 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.15 KFO96134.1 - 0.021 15.2 0.5 1.3 9.5 0.0 2.7 2 0 0 2 2 2 0 Immunoglobulin C1-set domain Malt_amylase_C PF16657.5 KFO96134.1 - 0.13 12.4 0.0 0.4 10.8 0.0 1.9 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain EphA2_TM PF14575.6 KFO96135.1 - 0.0042 17.9 0.0 0.005 17.7 0.0 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 KFO96135.1 - 0.021 14.8 0.6 0.04 13.9 0.7 1.5 1 1 0 1 1 1 0 Protocadherin DUF4381 PF14316.6 KFO96135.1 - 0.025 14.8 0.0 0.035 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) stn_TNFRSF12A PF12191.8 KFO96135.1 - 0.028 14.7 0.0 0.066 13.4 0.0 1.5 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Syndecan PF01034.20 KFO96135.1 - 0.14 12.1 0.4 0.23 11.4 0.4 1.3 1 0 0 1 1 1 0 Syndecan domain COX14 PF14880.6 KFO96135.1 - 0.14 12.0 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c assembly PhoR PF11808.8 KFO96135.1 - 0.18 12.2 0.0 0.28 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR V-set PF07686.17 KFO96136.1 - 2.1e-06 27.9 0.5 3.5e-06 27.1 0.5 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFO96136.1 - 2.1e-05 24.6 0.3 3.2e-05 24.0 0.3 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFO96136.1 - 0.0003 21.3 0.2 0.00048 20.7 0.2 1.3 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFO96136.1 - 0.019 15.0 0.3 0.035 14.2 0.3 1.6 1 1 0 1 1 1 0 Immunoglobulin I-set domain Herpes_gE PF02480.16 KFO96136.1 - 0.019 13.7 0.5 0.022 13.5 0.5 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PAN_4 PF14295.6 KFO96136.1 - 0.095 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 PAN domain CUB PF00431.20 KFO96137.1 - 2.5e-24 85.8 0.0 3.9e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 CUB domain Fz PF01392.22 KFO96137.1 - 4.8e-24 85.1 1.1 4.8e-24 85.1 1.1 1.7 2 0 0 2 2 2 1 Fz domain Ldl_recept_a PF00057.18 KFO96137.1 - 2.9e-10 40.2 9.4 2.9e-10 40.2 9.4 2.4 2 1 0 2 2 2 1 Low-density lipoprotein receptor domain class A C1q PF00386.21 KFO96138.1 - 3.1e-37 127.6 0.0 3.7e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFO96138.1 - 2.9e-10 39.7 34.1 5.1e-08 32.6 34.1 2.2 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) zf-C3HC4_3 PF13920.6 KFO96139.1 - 1.6e-13 50.3 12.4 2.4e-13 49.7 12.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFO96139.1 - 1.5e-07 31.2 10.2 2.5e-07 30.5 10.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KFO96139.1 - 2.7e-05 24.4 12.1 4.3e-05 23.8 12.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFO96139.1 - 0.022 14.7 12.2 0.043 13.8 12.1 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFO96139.1 - 0.027 14.3 13.7 0.049 13.5 13.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFO96139.1 - 2 8.5 8.5 0.64 10.1 5.4 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pox_P35 PF03213.14 KFO96139.1 - 4.2 6.5 4.4 6.4 5.9 4.4 1.2 1 0 0 1 1 1 0 Poxvirus P35 protein zf-RING_UBOX PF13445.6 KFO96139.1 - 4.3 7.4 9.3 12 6.0 9.5 1.7 1 1 0 1 1 1 0 RING-type zinc-finger Ig_3 PF13927.6 KFO96140.1 - 3.8e-28 97.9 2.7 5.8e-10 39.6 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.12 KFO96140.1 - 3.6e-24 84.7 2.9 2e-19 69.4 0.8 3.4 3 1 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 KFO96140.1 - 6e-22 77.8 0.9 4.3e-08 33.4 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFO96140.1 - 3.3e-20 72.0 0.7 3.2e-06 27.2 0.4 3.3 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFO96140.1 - 6.2e-18 64.6 0.1 1.9e-05 24.6 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain C1-set PF07654.15 KFO96140.1 - 3.1e-06 27.5 2.6 0.0012 19.2 0.3 3.3 3 0 0 3 3 3 1 Immunoglobulin C1-set domain Ig_4 PF16680.5 KFO96140.1 - 3.1e-05 24.1 0.8 0.36 11.1 0.2 3.6 3 1 1 4 4 4 2 T-cell surface glycoprotein CD3 delta chain V-set PF07686.17 KFO96140.1 - 4.5e-05 23.6 1.9 0.15 12.3 0.0 3.7 3 2 0 3 3 3 2 Immunoglobulin V-set domain Ig_5 PF16681.5 KFO96140.1 - 0.00034 21.0 0.3 0.28 11.6 0.0 3.4 3 0 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Insulin_TMD PF17870.1 KFO96140.1 - 0.0088 16.1 2.6 0.043 13.9 2.2 2.1 2 0 0 2 2 2 1 Insulin receptor trans-membrane segment FeoB_associated PF12669.7 KFO96140.1 - 0.25 11.7 5.6 0.52 10.7 5.6 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF3592 PF12158.8 KFO96140.1 - 0.27 11.3 0.1 0.27 11.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) Homeodomain PF00046.29 KFO96141.1 - 2.9e-25 87.8 6.1 6.4e-25 86.8 6.1 1.6 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 KFO96141.1 - 8.2e-10 38.2 3.3 1.4e-09 37.5 3.3 1.4 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 KFO96141.1 - 0.0006 19.7 0.2 0.0014 18.5 0.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain Aminotran_1_2 PF00155.21 KFO96142.1 - 2.9e-59 201.1 0.0 4.1e-59 200.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KFO96142.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase SbcD_C PF12320.8 KFO96142.1 - 0.064 13.6 0.1 0.21 11.9 0.0 1.8 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain 2OG-FeII_Oxy_2 PF13532.6 KFO96144.1 - 3.3e-19 69.9 0.0 5.7e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.25 KFO96145.1 - 1.6e-18 66.9 0.1 2e-18 66.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFO96145.1 - 1.9e-08 34.2 0.0 2.2e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RFXA_RFXANK_bdg PF15289.6 KFO96145.1 - 0.061 13.7 0.0 0.075 13.4 0.0 1.2 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain API5 PF05918.11 KFO96146.1 - 9.8e-193 641.7 0.0 1.1e-192 641.4 0.0 1.0 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.6 KFO96146.1 - 8.5e-05 22.9 0.1 0.00035 20.9 0.1 2.0 2 0 0 2 2 2 1 HEAT repeats MMS19_N PF14500.6 KFO96146.1 - 0.019 14.6 2.3 0.13 11.8 2.3 2.2 1 1 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II Dak2 PF02734.17 KFO96146.1 - 0.023 14.6 0.0 0.069 13.0 0.0 1.7 1 1 0 1 1 1 0 DAK2 domain LRR_8 PF13855.6 KFO96147.1 - 8.8e-38 127.9 26.2 5.4e-12 45.3 0.5 5.4 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KFO96147.1 - 9.7e-21 73.5 23.7 2.5e-07 30.9 0.7 5.8 3 2 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFO96147.1 - 1.4e-20 73.5 0.0 1.7e-12 47.4 0.0 2.8 2 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) I-set PF07679.16 KFO96147.1 - 1e-13 51.1 0.0 1.9e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFO96147.1 - 4.7e-12 45.9 1.2 1e-11 44.8 0.1 2.2 3 0 0 3 3 3 1 Immunoglobulin domain Ig_3 PF13927.6 KFO96147.1 - 8e-11 42.4 0.6 3.5e-10 40.3 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFO96147.1 - 2e-07 31.2 0.7 1.7e-05 24.9 0.7 2.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KFO96147.1 - 1.2e-06 28.8 1.0 2.2e-06 27.9 0.1 1.9 2 0 0 2 2 1 1 Immunoglobulin domain LRR_9 PF14580.6 KFO96147.1 - 0.00017 21.2 7.4 0.0068 15.9 0.4 3.2 1 1 3 4 4 4 3 Leucine-rich repeat Ig_6 PF18452.1 KFO96147.1 - 0.00031 20.2 0.4 0.00099 18.6 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain LRR_1 PF00560.33 KFO96147.1 - 0.0015 18.8 29.5 0.54 11.0 0.0 8.3 8 1 0 8 8 8 2 Leucine Rich Repeat Meckelin PF09773.9 KFO96147.1 - 0.016 13.3 0.1 0.15 10.2 0.0 2.1 2 0 0 2 2 2 0 Meckelin (Transmembrane protein 67) LRRNT PF01462.18 KFO96147.1 - 0.018 14.7 2.8 0.018 14.7 2.8 2.5 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain Podoplanin PF05808.11 KFO96147.1 - 0.068 13.3 5.9 0.15 12.2 5.9 1.6 1 0 0 1 1 1 0 Podoplanin Insulin_TMD PF17870.1 KFO96147.1 - 0.12 12.5 0.7 0.31 11.2 0.7 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment LRR_6 PF13516.6 KFO96147.1 - 7.2 6.9 23.2 25 5.3 0.2 7.1 7 0 0 7 7 7 0 Leucine Rich repeat RVT_1 PF00078.27 KFO96148.1 - 0.00019 21.0 0.0 0.00026 20.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.11 KFO96148.1 - 0.26 11.0 0.6 0.43 10.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) RAG2 PF03089.14 KFO96149.1 - 1.8e-178 592.7 0.1 2.3e-178 592.4 0.1 1.1 1 0 0 1 1 1 1 Recombination activating protein 2 RAG2_PHD PF13341.6 KFO96149.1 - 1.5e-44 149.9 1.2 3.2e-44 148.8 1.2 1.6 1 0 0 1 1 1 1 RAG2 PHD domain Kelch_3 PF13415.6 KFO96149.1 - 7.1e-10 38.9 0.0 3.5e-05 24.0 0.0 4.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KFO96149.1 - 9.6e-06 25.5 0.7 0.46 10.5 0.1 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 KFO96149.1 - 0.0003 20.7 1.4 28 4.8 0.1 4.7 5 0 0 5 5 5 0 Galactose oxidase, central domain PHD PF00628.29 KFO96149.1 - 0.012 15.5 2.2 0.015 15.1 0.1 2.3 3 0 0 3 3 3 0 PHD-finger Kelch_6 PF13964.6 KFO96149.1 - 0.04 14.2 0.3 2.3 8.6 0.0 3.5 4 0 0 4 4 4 0 Kelch motif CAF1C_H4-bd PF12265.8 KFO96149.1 - 0.077 13.3 0.0 0.49 10.7 0.0 2.3 2 0 0 2 2 2 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex WRNPLPNID PF15017.6 KFO96149.1 - 3.5 8.6 8.3 11 7.0 8.3 1.9 1 1 0 1 1 1 0 Putative WW-binding domain and destruction box RAG1 PF12940.7 KFO96150.1 - 0 1236.4 1.1 0 1235.7 1.1 1.2 1 0 0 1 1 1 1 Recombination-activation protein 1 (RAG1), recombinase RAG1_imp_bd PF12560.8 KFO96150.1 - 3.1e-111 371.5 4.2 7e-111 370.3 4.2 1.6 1 0 0 1 1 1 1 RAG1 importin binding zf-RAG1 PF10426.9 KFO96150.1 - 5e-17 61.7 10.5 8.1e-16 57.9 2.4 2.7 2 0 0 2 2 2 2 Recombination-activating protein 1 zinc-finger domain zf-C3HC4 PF00097.25 KFO96150.1 - 6.2e-07 29.2 14.6 6.2e-07 29.2 14.6 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFO96150.1 - 0.00012 21.9 13.7 0.00012 21.9 13.7 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KFO96150.1 - 0.00013 21.8 12.8 0.00023 21.0 8.7 2.6 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KFO96150.1 - 0.013 15.7 13.4 0.013 15.7 13.4 2.9 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KFO96150.1 - 0.29 11.3 18.2 0.03 14.4 10.5 3.3 3 0 0 3 3 3 0 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 KFO96150.1 - 0.65 10.1 18.6 0.083 12.9 13.2 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-TRAF PF02176.18 KFO96151.1 - 1.2e-23 83.5 27.7 3.6e-18 66.0 3.3 3.9 2 1 1 3 3 3 2 TRAF-type zinc finger TRAF6_Z2 PF18048.1 KFO96151.1 - 5.2e-17 61.6 7.2 5.2e-17 61.6 7.2 4.7 6 0 0 6 6 4 1 TNF receptor-associated factor 6 zinc finger 2 zf-C3HC4_2 PF13923.6 KFO96151.1 - 1.2e-09 37.8 5.7 1.2e-09 37.8 5.7 3.9 2 1 2 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFO96151.1 - 1e-08 34.9 5.2 1e-08 34.9 5.2 4.1 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFO96151.1 - 3.1e-07 30.1 4.7 3.1e-07 30.1 4.7 3.6 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFO96151.1 - 4.6e-07 30.1 4.5 4.6e-07 30.1 4.5 3.8 2 1 2 4 4 3 1 Ring finger domain zf-RING_UBOX PF13445.6 KFO96151.1 - 1e-06 28.6 5.9 1e-06 28.6 5.9 2.8 3 1 0 3 3 1 1 RING-type zinc-finger zf-TRAF_2 PF15965.5 KFO96151.1 - 3.4e-06 27.4 28.7 4.8e-06 26.9 5.2 3.7 2 1 2 4 4 4 2 TRAF-like zinc-finger zf-C3HC4_4 PF15227.6 KFO96151.1 - 4.1e-06 26.9 4.0 4.1e-06 26.9 4.0 3.7 2 1 2 4 4 3 1 zinc finger of C3HC4-type, RING SlyX PF04102.12 KFO96151.1 - 9.4e-05 22.9 3.4 9.4e-05 22.9 3.4 2.2 2 0 0 2 2 1 1 SlyX zf-RING_5 PF14634.6 KFO96151.1 - 0.00044 20.2 5.6 0.00044 20.2 5.6 4.2 2 2 1 3 3 2 1 zinc-RING finger domain Med21 PF11221.8 KFO96151.1 - 0.0018 18.6 2.9 0.0036 17.5 2.9 1.6 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Tropomyosin_1 PF12718.7 KFO96151.1 - 0.0033 17.6 1.3 0.0062 16.7 1.3 1.3 1 0 0 1 1 1 1 Tropomyosin like PspA_IM30 PF04012.12 KFO96151.1 - 0.0057 16.3 1.4 0.015 14.9 1.4 1.7 1 0 0 1 1 1 1 PspA/IM30 family Sina PF03145.16 KFO96151.1 - 0.008 16.1 25.0 0.049 13.6 6.5 3.9 2 1 2 4 4 4 2 Seven in absentia protein family UPF0242 PF06785.11 KFO96151.1 - 0.01 16.0 1.5 0.022 14.9 1.5 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF16 PF01519.16 KFO96151.1 - 0.012 16.1 2.0 0.03 14.8 1.5 1.9 2 0 0 2 2 1 0 Protein of unknown function DUF16 U-box PF04564.15 KFO96151.1 - 0.012 15.8 0.1 0.068 13.4 0.0 2.3 3 0 0 3 3 1 0 U-box domain CENP-F_leu_zip PF10473.9 KFO96151.1 - 0.014 15.4 0.9 0.039 14.0 0.9 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-RING_11 PF17123.5 KFO96151.1 - 0.015 15.0 3.4 0.056 13.2 3.4 2.1 1 0 0 1 1 1 0 RING-like zinc finger Prok-RING_4 PF14447.6 KFO96151.1 - 0.019 14.8 4.9 0.019 14.8 4.9 3.8 2 2 2 4 4 2 0 Prokaryotic RING finger family 4 DUF4455 PF14643.6 KFO96151.1 - 0.022 13.4 0.5 0.036 12.7 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) HMMR_N PF15905.5 KFO96151.1 - 0.023 14.2 0.7 0.038 13.5 0.7 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 KFO96151.1 - 0.028 13.3 0.6 0.05 12.5 0.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein TSC22 PF01166.18 KFO96151.1 - 0.032 14.5 1.4 2.1 8.7 0.5 3.1 1 1 1 2 2 2 0 TSC-22/dip/bun family Spc29 PF17082.5 KFO96151.1 - 0.05 13.4 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Spindle Pole Component 29 DUF1664 PF07889.12 KFO96151.1 - 0.051 13.6 1.0 0.12 12.4 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF465 PF04325.13 KFO96151.1 - 0.054 13.5 0.3 7.5 6.7 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF465) zf-RAG1 PF10426.9 KFO96151.1 - 0.063 13.4 1.3 0.4 10.8 0.2 3.0 2 0 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain DUF2730 PF10805.8 KFO96151.1 - 0.085 13.0 0.2 0.2 11.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF3552 PF12072.8 KFO96151.1 - 0.088 12.2 1.3 0.17 11.3 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Tropomyosin PF00261.20 KFO96151.1 - 0.14 11.5 2.3 0.24 10.8 2.3 1.2 1 0 0 1 1 1 0 Tropomyosin AAA_13 PF13166.6 KFO96151.1 - 0.17 10.5 1.1 0.27 9.8 1.1 1.2 1 0 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.8 KFO96151.1 - 0.18 11.9 2.4 0.33 11.0 2.4 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 KFO96151.1 - 0.19 11.8 3.4 0.39 10.8 3.4 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding zf-C2H2_4 PF13894.6 KFO96151.1 - 0.42 11.6 0.2 0.42 11.6 0.2 5.8 6 0 0 6 6 4 0 C2H2-type zinc finger TACC_C PF05010.14 KFO96151.1 - 1.4 8.6 7.3 0.095 12.5 1.8 1.7 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Cortex-I_coil PF09304.10 KFO96151.1 - 2.3 8.5 4.6 1.2 9.3 1.0 2.3 3 0 0 3 3 2 0 Cortexillin I, coiled coil SAND PF01342.21 KFO96151.1 - 3.6 7.4 5.7 2.9 7.7 2.6 2.3 1 1 1 2 2 2 0 SAND domain DM PF00751.18 KFO96151.1 - 5.9 6.9 17.8 8.5 6.4 3.8 3.4 1 1 2 3 3 3 0 DM DNA binding domain HbrB PF08539.11 KFO96152.1 - 5.1e-11 42.9 0.9 1.8e-08 34.6 0.1 2.5 1 1 1 2 2 2 2 HbrB-like COMM_domain PF07258.14 KFO96153.1 - 7.7e-24 83.6 0.0 1.5e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 COMM domain Ldl_recept_a PF00057.18 KFO96154.1 - 7.3e-33 112.5 46.2 6.4e-12 45.5 9.5 3.5 4 0 0 4 4 4 3 Low-density lipoprotein receptor domain class A RCR PF12273.8 KFO96154.1 - 0.013 16.1 0.0 0.058 14.0 0.0 1.9 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red PspB PF06667.12 KFO96154.1 - 0.25 11.4 0.4 0.54 10.4 0.4 1.4 1 0 0 1 1 1 0 Phage shock protein B EGF_Tenascin PF18720.1 KFO96154.1 - 1.8 8.7 10.7 4.5 7.4 1.2 3.9 3 0 0 3 3 3 0 Tenascin EGF domain Trypsin PF00089.26 KFO96155.1 - 4.7e-37 127.9 0.1 7.2e-37 127.3 0.1 1.2 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 KFO96155.1 - 1.1e-24 86.9 0.2 2.4e-24 85.8 0.0 1.7 2 0 0 2 2 2 1 CUB domain Sushi PF00084.20 KFO96155.1 - 1.1e-14 54.8 8.4 1.3e-07 32.1 0.3 3.3 3 0 0 3 3 3 2 Sushi repeat (SCR repeat) EGF PF00008.27 KFO96155.1 - 1.2e-08 35.1 6.6 1.2e-08 35.1 6.6 4.0 4 0 0 4 4 4 1 EGF-like domain hEGF PF12661.7 KFO96155.1 - 0.00019 22.0 2.0 0.00019 22.0 2.0 4.2 2 0 0 2 2 2 1 Human growth factor-like EGF EGF_2 PF07974.13 KFO96155.1 - 0.0049 17.2 8.4 0.0049 17.2 8.4 4.7 5 1 0 5 5 5 1 EGF-like domain CUB_2 PF02408.20 KFO96155.1 - 0.014 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 CUB-like domain SDF PF00375.18 KFO96156.1 - 4.8e-123 411.0 28.6 5.5e-123 410.8 28.6 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Xlink PF00193.17 KFO96157.1 - 1.2e-20 73.7 0.5 2.9e-20 72.5 0.0 1.8 2 0 0 2 2 2 1 Extracellular link domain DUF5082 PF16888.5 KFO96157.1 - 0.12 12.7 0.1 0.24 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) LYRIC PF15686.5 KFO96157.1 - 0.14 11.7 2.0 0.12 11.9 0.6 1.6 1 1 1 2 2 2 0 Lysine-rich CEACAM1 co-isolated protein family TMEM51 PF15345.6 KFO96157.1 - 0.2 11.5 0.1 0.2 11.5 0.1 1.9 2 1 0 2 2 2 0 Transmembrane protein 51 2-oxoacid_dh PF00198.23 KFO96158.1 - 1.3e-76 257.1 0.2 1.6e-76 256.8 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFO96158.1 - 7.6e-21 73.7 0.5 1.7e-20 72.6 0.5 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KFO96158.1 - 8.7e-11 42.0 0.0 2.6e-10 40.5 0.0 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KFO96158.1 - 9e-05 22.2 0.0 0.012 15.4 0.0 2.9 2 1 1 3 3 3 1 Biotin-lipoyl like Aldolase_II PF00596.21 KFO96159.1 - 1.8e-45 155.1 0.0 2.1e-45 154.9 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF4635 PF15466.6 KFO96159.1 - 0.12 11.9 0.0 3.7 7.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) Ets PF00178.22 KFO96160.1 - 1.6e-33 115.0 3.6 5.6e-33 113.3 0.6 2.4 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.16 KFO96160.1 - 8.1e-25 86.6 3.8 8.8e-25 86.5 2.6 1.7 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain PH PF00169.29 KFO96161.1 - 9.5e-08 32.5 0.0 2.7e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 PH domain ERM PF00769.19 KFO96161.1 - 0.0088 15.9 28.7 0.0088 15.9 28.7 2.5 2 1 0 2 2 2 1 Ezrin/radixin/moesin family KNOX2 PF03791.13 KFO96161.1 - 0.029 13.9 0.1 0.029 13.9 0.1 3.3 5 0 0 5 5 5 0 KNOX2 domain Glyco_trans_1_2 PF13524.6 KFO96161.1 - 0.22 11.9 2.9 3.8 8.0 0.2 2.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 Lebercilin PF15619.6 KFO96161.1 - 3.4 7.3 58.9 3.5 7.2 23.4 2.4 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Zip PF02535.22 KFO96162.1 - 4.1e-36 124.9 20.2 7.8e-29 100.9 12.3 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter DUF996 PF06195.13 KFO96162.1 - 0.64 10.3 5.2 0.56 10.5 2.8 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF996) ER PF01133.17 KFO96163.1 - 5.9e-46 154.5 0.2 6.7e-46 154.3 0.2 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary BA14K PF07886.11 KFO96163.1 - 0.11 12.4 1.2 0.25 11.3 1.2 1.6 1 0 0 1 1 1 0 BA14K-like protein Glycos_transf_2 PF00535.26 KFO96164.1 - 3.4e-26 92.0 0.0 5.4e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFO96164.1 - 1.7e-17 63.9 2.4 2.9e-17 63.1 2.4 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_2 PF10111.9 KFO96164.1 - 7.5e-08 32.2 0.0 2.3e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 KFO96164.1 - 8.2e-08 32.4 0.0 1.4e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KFO96164.1 - 1.1e-05 25.0 0.1 2.1e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase DUF4227 PF14004.6 KFO96164.1 - 0.086 12.8 0.4 0.16 11.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) DUF4897 PF16238.5 KFO96164.1 - 0.17 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) DNA_pol_A_exo1 PF01612.20 KFO96165.1 - 4.4e-15 55.8 0.0 7.4e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease RRXRR PF14239.6 KFO96165.1 - 0.034 14.0 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 RRXRR protein WD40 PF00400.32 KFO96166.1 - 1.3e-12 48.0 10.4 0.0047 17.7 0.1 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat Frtz PF11768.8 KFO96166.1 - 0.059 11.7 0.0 0.09 11.1 0.0 1.1 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Spectrin PF00435.21 KFO96167.1 - 5.4e-75 248.6 25.9 1.1e-25 90.2 6.9 4.3 4 0 0 4 4 4 4 Spectrin repeat CH PF00307.31 KFO96167.1 - 2e-50 169.5 0.1 4.4e-25 88.0 0.0 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KFO96167.1 - 8e-27 93.1 0.0 3.4e-26 91.1 0.0 2.2 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_1 PF00036.32 KFO96167.1 - 2.3e-07 29.9 1.0 0.0097 15.4 0.2 3.3 3 0 0 3 3 3 2 EF hand CAMSAP_CH PF11971.8 KFO96167.1 - 9.2e-07 28.6 0.0 5e-05 23.0 0.0 2.6 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_7 PF13499.6 KFO96167.1 - 2e-06 28.1 0.1 1.6e-05 25.3 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KFO96167.1 - 6.6e-05 22.7 1.1 0.002 18.0 0.4 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KFO96167.1 - 0.00031 20.5 1.8 0.03 14.2 0.1 3.8 4 0 0 4 4 3 1 EF-hand domain XisI PF08869.11 KFO96167.1 - 0.0091 16.3 0.9 0.033 14.5 0.9 2.0 1 0 0 1 1 1 1 XisI protein EF-hand_11 PF08976.11 KFO96167.1 - 0.075 13.9 0.2 0.34 11.8 0.1 2.2 2 0 0 2 2 1 0 EF-hand domain Uds1 PF15456.6 KFO96167.1 - 0.29 11.3 11.0 0.16 12.1 2.4 3.5 3 0 0 3 3 3 0 Up-regulated During Septation U3_assoc_6 PF08640.11 KFO96167.1 - 0.81 9.8 4.0 1.5 8.9 0.1 3.3 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 6 RRM_1 PF00076.22 KFO96168.1 - 4.3e-34 116.1 0.1 1.6e-16 59.9 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFO96168.1 - 2.1e-08 34.1 0.3 9e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif RRM_5 PF13893.6 KFO96168.1 - 1.3e-05 24.8 0.0 0.054 13.1 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFO96168.1 - 8.7e-05 22.3 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KFO96168.1 - 0.0073 16.3 0.2 0.067 13.2 0.1 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DbpA PF03880.15 KFO96168.1 - 0.038 14.0 0.1 4.2 7.4 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain SET_assoc PF11767.8 KFO96168.1 - 0.096 12.3 0.2 1 9.1 0.1 2.3 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated Presenilin PF01080.17 KFO96168.1 - 1.7 7.3 8.8 2.1 7.0 8.8 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 KFO96168.1 - 2.9 6.1 14.8 3.3 5.9 14.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Rad51 PF08423.11 KFO96171.1 - 8.7e-38 130.0 0.0 1e-37 129.8 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KFO96171.1 - 6.2e-11 42.2 0.0 8.4e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KFO96171.1 - 2.1e-07 30.6 0.7 1.1e-06 28.2 0.7 2.2 1 1 0 1 1 1 1 KaiC RecA PF00154.21 KFO96171.1 - 1.7e-05 24.4 0.1 0.027 14.0 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein DnaB_C PF03796.15 KFO96171.1 - 5e-05 22.8 0.1 0.0015 18.0 0.1 2.2 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain PAXNEB PF05625.11 KFO96171.1 - 0.01 15.0 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 PAXNEB protein DUF5522 PF17653.1 KFO96171.1 - 0.048 13.6 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5522) AAA PF00004.29 KFO96171.1 - 0.1 13.0 0.0 0.43 11.0 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KFO96171.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_trans_CmpB PF06541.11 KFO96172.1 - 8.6e-10 39.0 10.8 1.1e-09 38.7 10.8 1.1 1 0 0 1 1 1 1 Putative ABC-transporter type IV PIG-H PF10181.9 KFO96173.1 - 4.6e-16 58.4 0.2 8.2e-16 57.6 0.2 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Arginase PF00491.21 KFO96174.1 - 3.1e-68 230.3 0.0 3.6e-68 230.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family V-SNARE_C PF12352.8 KFO96175.1 - 8.3e-21 74.0 8.1 8.3e-21 74.0 8.1 2.3 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 KFO96175.1 - 6.6e-13 48.9 4.9 6.6e-13 48.9 4.9 2.2 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 KFO96175.1 - 1.7e-05 24.6 1.9 1.7e-05 24.6 1.9 1.8 2 0 0 2 2 2 1 Sec20 YqjK PF13997.6 KFO96175.1 - 0.011 15.9 2.5 0.69 10.2 0.0 2.5 3 0 0 3 3 3 0 YqjK-like protein FAM184 PF15665.5 KFO96175.1 - 0.026 14.3 5.9 0.031 14.0 5.9 1.1 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Fusion_gly PF00523.18 KFO96175.1 - 0.031 12.5 3.0 0.047 11.9 3.0 1.3 1 1 0 1 1 1 0 Fusion glycoprotein F0 Laminin_II PF06009.12 KFO96175.1 - 0.034 14.2 4.3 0.059 13.4 0.8 2.2 2 1 0 2 2 2 0 Laminin Domain II DUF745 PF05335.13 KFO96175.1 - 0.098 12.4 5.2 1.3 8.8 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Snapin_Pallidin PF14712.6 KFO96175.1 - 0.15 12.5 13.2 0.1 13.1 1.2 2.6 2 1 0 2 2 2 0 Snapin/Pallidin SNARE PF05739.19 KFO96175.1 - 0.15 12.1 1.3 0.83 9.7 0.4 2.3 2 0 0 2 2 2 0 SNARE domain DUF3958 PF13125.6 KFO96175.1 - 0.58 10.4 10.6 0.13 12.5 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) HalX PF08663.10 KFO96175.1 - 0.59 10.5 8.3 5.3 7.4 1.7 2.4 2 0 0 2 2 2 0 HalX domain KxDL PF10241.9 KFO96175.1 - 1.6 9.1 9.3 4.4 7.6 1.1 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein HAUS-augmin3 PF14932.6 KFO96175.1 - 2.6 7.6 7.9 1.2 8.7 3.1 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Exonuc_VII_L PF02601.15 KFO96175.1 - 5 6.6 9.3 13 5.3 9.3 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit Tho2 PF11262.8 KFO96175.1 - 7.6 5.6 9.9 1.5 8.0 2.8 2.6 2 1 1 3 3 3 0 Transcription factor/nuclear export subunit protein 2 TPR_2 PF07719.17 KFO96176.1 - 0.004 17.2 0.2 0.022 14.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat FYVE PF01363.21 KFO96177.1 - 1e-16 60.8 16.0 1.9e-16 59.9 16.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KFO96177.1 - 0.11 12.7 11.3 0.31 11.2 11.3 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger Glyoxalase_2 PF12681.7 KFO96177.1 - 0.13 12.2 0.1 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Glyoxalase-like domain DUF771 PF05595.11 KFO96177.1 - 0.16 12.0 0.8 0.59 10.1 0.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF771) zf-B_box PF00643.24 KFO96177.1 - 8.2 6.7 14.5 0.63 10.2 6.5 2.7 1 1 1 2 2 2 0 B-box zinc finger Stonin2_N PF12016.8 KFO96178.1 - 0.093 12.1 4.7 0.17 11.2 4.7 1.3 1 0 0 1 1 1 0 Stonin 2 Gal-bind_lectin PF00337.22 KFO96179.1 - 1.6e-32 111.8 0.0 1.8e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin PH PF00169.29 KFO96180.1 - 2.2e-32 111.7 0.0 1.4e-15 57.6 0.0 2.4 2 0 0 2 2 2 2 PH domain DEP PF00610.21 KFO96180.1 - 1.3e-15 57.2 0.0 3e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_11 PF15413.6 KFO96180.1 - 1.2e-08 35.3 2.9 0.0065 16.9 0.4 4.0 3 1 0 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.6 KFO96180.1 - 6.3e-08 33.0 0.0 0.013 15.9 0.1 3.1 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 KFO96180.1 - 0.003 17.8 0.2 0.27 11.5 0.2 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 KFO96180.1 - 0.0034 17.5 0.1 2 8.6 0.0 2.7 3 0 0 3 3 3 2 PH domain PH_6 PF15406.6 KFO96180.1 - 0.0089 16.3 0.0 0.68 10.2 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain PH_2 PF08458.10 KFO96180.1 - 0.016 15.6 0.0 7.1 7.0 0.0 2.6 3 0 0 3 3 3 0 Plant pleckstrin homology-like region PH_16 PF17838.1 KFO96180.1 - 0.11 12.3 0.0 4.7 7.1 0.0 2.5 2 0 0 2 2 2 0 PH domain ATG11 PF10377.9 KFO96180.1 - 0.11 12.5 0.0 1.1 9.3 0.0 2.2 2 1 0 2 2 2 0 Autophagy-related protein 11 EIF_2_alpha PF07541.12 KFO96181.1 - 1.1e-36 125.4 0.0 2.2e-36 124.4 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KFO96181.1 - 1.1e-15 57.7 0.7 2.7e-15 56.5 0.7 1.6 1 0 0 1 1 1 1 S1 RNA binding domain SoDot-IcmSS PF16848.5 KFO96181.1 - 0.069 13.1 0.5 0.26 11.3 0.1 2.1 2 0 0 2 2 2 0 Substrate of the Dot/Icm secretion system, putative DUF4453 PF14627.6 KFO96181.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) ATP-synt_D PF01813.17 KFO96182.1 - 3.6e-76 255.4 8.6 4.9e-76 254.9 8.6 1.2 1 0 0 1 1 1 1 ATP synthase subunit D DUF4249 PF14054.6 KFO96182.1 - 0.049 13.3 0.1 0.064 12.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4249) Guanylate_kin PF00625.21 KFO96183.1 - 9.8e-52 175.3 0.0 2.4e-51 174.0 0.0 1.7 1 0 0 1 1 1 1 Guanylate kinase L27_N PF09060.10 KFO96183.1 - 3e-24 84.8 3.7 9.1e-24 83.3 3.7 1.9 1 0 0 1 1 1 1 L27_N SH3_2 PF07653.17 KFO96183.1 - 2e-12 46.6 0.0 4.7e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PDZ PF00595.24 KFO96183.1 - 1.2e-11 44.8 0.6 2.4e-11 43.8 0.6 1.6 1 0 0 1 1 1 1 PDZ domain L27 PF02828.16 KFO96183.1 - 1.8e-09 37.2 3.3 2e-09 37.0 1.2 2.2 2 0 0 2 2 2 1 L27 domain PDZ_6 PF17820.1 KFO96183.1 - 2.4e-09 36.9 0.0 6.6e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 PDZ domain SH3_1 PF00018.28 KFO96183.1 - 2e-06 27.3 0.3 7.1e-06 25.5 0.3 2.0 1 1 0 1 1 1 1 SH3 domain PDZ_2 PF13180.6 KFO96183.1 - 6.1e-06 26.5 0.1 1.7e-05 25.0 0.1 1.8 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.6 KFO96183.1 - 0.0003 20.6 0.1 0.00067 19.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain MMR_HSR1 PF01926.23 KFO96183.1 - 0.023 14.8 0.0 0.2 11.8 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SpoU_sub_bind PF08032.12 KFO96183.1 - 0.54 10.6 3.0 16 5.8 0.0 4.0 3 1 1 4 4 4 0 RNA 2'-O ribose methyltransferase substrate binding MoCF_biosynth PF00994.24 KFO96184.1 - 6.3e-67 223.7 0.0 6.3e-39 132.9 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KFO96184.1 - 6.1e-42 143.1 1.4 1.2e-41 142.1 0.5 1.9 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KFO96184.1 - 2.2e-23 82.2 0.0 5.8e-23 80.9 0.0 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Tubulin-binding PF00418.19 KFO96184.1 - 0.18 11.9 0.1 0.38 10.8 0.1 1.5 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat BMF PF15185.6 KFO96185.1 - 5.5e-113 375.3 1.3 6.2e-113 375.1 1.3 1.0 1 0 0 1 1 1 1 Bcl-2-modifying factor, apoptosis SRP14 PF02290.15 KFO96186.1 - 1.4e-24 86.3 0.1 1.4e-24 86.3 0.1 1.5 2 0 0 2 2 2 1 Signal recognition particle 14kD protein DUF3509 PF12021.8 KFO96186.1 - 0.15 11.8 0.0 2.3 8.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3509) 7tm_1 PF00001.21 KFO96187.1 - 1.8e-30 106.2 28.8 2.3e-30 105.8 28.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FSIP1 PF15554.6 KFO96188.1 - 1.8e-26 93.2 1.1 2e-26 93.0 1.1 1.0 1 0 0 1 1 1 1 FSIP1 family DUF4699 PF15770.5 KFO96188.1 - 0.003 17.4 0.6 0.0035 17.2 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4699) DUF1815 PF08844.10 KFO96189.1 - 0.077 13.0 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) TSP_C PF05735.12 KFO96190.1 - 3.7e-69 232.6 0.7 5.3e-69 232.1 0.7 1.2 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.18 KFO96190.1 - 8.5e-59 194.9 151.3 2.5e-12 46.2 13.6 10.3 9 2 2 11 11 11 9 Thrombospondin type 3 repeat TSP_1 PF00090.19 KFO96190.1 - 1.2e-39 134.2 47.0 5e-16 58.7 8.5 5.2 6 0 0 6 6 6 3 Thrombospondin type 1 domain VWC PF00093.18 KFO96190.1 - 1.3e-12 47.9 17.8 1.3e-12 47.9 17.8 6.7 4 3 1 5 5 5 1 von Willebrand factor type C domain EGF_3 PF12947.7 KFO96190.1 - 1.4e-06 28.4 10.5 1.4e-06 28.4 10.5 6.2 5 0 0 5 5 5 2 EGF domain EGF_CA PF07645.15 KFO96190.1 - 9.4e-06 25.7 2.2 9.4e-06 25.7 2.2 5.9 5 0 0 5 5 5 3 Calcium-binding EGF domain cEGF PF12662.7 KFO96190.1 - 1.4e-05 24.9 2.0 1.4e-05 24.9 2.0 5.2 4 0 0 4 4 4 2 Complement Clr-like EGF-like Laminin_G_3 PF13385.6 KFO96190.1 - 7.8e-05 22.9 0.7 0.0008 19.6 0.0 2.2 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 KFO96190.1 - 0.0012 19.0 11.8 0.0012 19.0 11.8 7.0 6 1 1 7 7 7 2 EGF-like domain Laminin_G_2 PF02210.24 KFO96190.1 - 0.0038 17.8 0.2 0.0086 16.7 0.2 1.5 1 0 0 1 1 1 1 Laminin G domain Katanin_con80 PF13925.6 KFO96191.1 - 4.4e-42 143.8 0.1 6.6e-42 143.3 0.1 1.3 1 0 0 1 1 1 1 con80 domain of Katanin DUF2012 PF09430.10 KFO96192.1 - 2.2e-30 105.3 0.1 3e-30 104.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) 7tm_1 PF00001.21 KFO96193.1 - 4e-76 255.8 5.4 5.1e-76 255.5 5.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFO96193.1 - 2e-09 37.5 8.0 2e-09 37.5 8.0 1.8 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFO96193.1 - 3.1e-05 23.9 3.3 3.1e-05 23.9 3.3 2.4 2 1 0 2 2 2 2 Olfactory receptor DUF2417 PF10329.9 KFO96193.1 - 3.5 7.0 12.6 9.6 5.6 8.5 2.7 2 1 0 2 2 2 0 Region of unknown function (DUF2417) MBT PF02820.18 KFO96194.1 - 5.7e-95 311.7 5.9 1.6e-31 108.5 0.1 3.1 3 0 0 3 3 3 3 mbt repeat zf-C2HC PF01530.18 KFO96194.1 - 6.8e-05 23.0 4.9 0.00018 21.6 4.9 1.7 1 0 0 1 1 1 1 Zinc finger, C2HC type Calci_bind_CcbP PF11535.8 KFO96194.1 - 0.077 13.5 0.1 0.25 11.8 0.0 1.9 2 0 0 2 2 2 0 Calcium binding SWIRM-assoc_2 PF16496.5 KFO96194.1 - 0.84 8.4 4.6 3.8 6.3 0.2 2.4 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal Tudor-knot PF11717.8 KFO96194.1 - 1.3 9.0 5.6 3.8 7.5 0.1 2.9 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain DUF2371 PF10177.9 KFO96195.1 - 3.1e-61 205.6 0.0 5.3e-61 204.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2371) Neurensin PF14927.6 KFO96195.1 - 0.025 14.3 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Neurensin DUF202 PF02656.15 KFO96195.1 - 0.056 13.9 0.1 11 6.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) RbcS PF12338.8 KFO96195.1 - 0.081 13.1 0.3 0.33 11.2 0.3 2.1 1 0 0 1 1 1 0 Ribulose-1,5-bisphosphate carboxylase small subunit DUF63 PF01889.17 KFO96195.1 - 0.15 12.2 0.1 0.25 11.5 0.1 1.2 1 0 0 1 1 1 0 Membrane protein of unknown function DUF63 4_1_CTD PF05902.13 KFO96196.1 - 1.4e-32 112.0 6.8 1.4e-32 112.0 6.8 3.9 5 1 0 5 5 5 1 4.1 protein C-terminal domain (CTD) FERM_C PF09380.10 KFO96196.1 - 1e-24 86.7 0.0 2.5e-24 85.5 0.0 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain SAB PF04382.13 KFO96196.1 - 1.1e-23 83.0 1.9 5.5e-23 80.8 1.9 2.4 1 0 0 1 1 1 1 SAB domain FERM_M PF00373.18 KFO96196.1 - 1.1e-20 74.2 2.3 9.3e-20 71.2 0.0 3.1 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.10 KFO96196.1 - 1.3e-18 66.7 0.3 4e-18 65.1 0.2 2.0 2 0 0 2 2 2 1 FERM N-terminal domain FA PF08736.11 KFO96196.1 - 6e-18 64.7 3.8 3.6e-17 62.2 3.8 2.5 1 0 0 1 1 1 1 FERM adjacent (FA) AKAP7_NLS PF10469.9 KFO96198.1 - 6.5e-38 130.7 0.9 9.3e-38 130.2 0.9 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain AKAP7_RIRII_bdg PF10470.9 KFO96198.1 - 3.1e-34 116.8 4.1 3.1e-34 116.8 4.1 1.8 2 0 0 2 2 2 1 PKA-RI-RII subunit binding domain of A-kinase anchor protein 2_5_RNA_ligase2 PF13563.6 KFO96198.1 - 5.4e-07 29.6 0.0 1.1e-06 28.6 0.0 1.5 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily Corona_NS2A PF05213.12 KFO96198.1 - 0.0044 16.4 0.0 0.0063 15.9 0.0 1.2 1 0 0 1 1 1 1 Coronavirus NS2A protein HU-CCDC81_euk_2 PF18289.1 KFO96198.1 - 0.065 13.4 0.4 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 CCDC81 eukaryotic HU domain 2 LigT_PEase PF02834.16 KFO96198.1 - 0.12 12.5 0.2 3.9 7.7 0.0 2.7 3 1 0 3 3 3 0 LigT like Phosphoesterase MutS_V PF00488.21 KFO96199.1 - 1.3e-51 175.3 0.1 2.4e-51 174.5 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFO96199.1 - 3.4e-26 92.6 0.5 6.4e-26 91.8 0.5 1.5 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 KFO96199.1 - 4.4e-13 49.4 0.0 9.3e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_14 PF13173.6 KFO96199.1 - 0.086 12.9 0.0 0.24 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF4828 PF16110.5 KFO96199.1 - 0.14 12.6 0.0 1.3 9.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4828) Med23 PF11573.8 KFO96200.1 - 0 2040.2 11.0 0 2040.0 11.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 23 Phosphodiest PF01663.22 KFO96201.1 - 1.3e-86 291.4 0.2 1.8e-86 291.0 0.2 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.17 KFO96201.1 - 3.3e-14 53.0 41.1 1.8e-07 31.4 14.8 3.0 3 0 0 3 3 3 2 Somatomedin B domain Endonuclease_NS PF01223.23 KFO96201.1 - 8.9e-13 48.6 0.1 1.4e-12 47.9 0.1 1.3 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Metalloenzyme PF01676.18 KFO96201.1 - 2.4e-05 23.8 0.0 4.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KFO96201.1 - 0.0029 17.1 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 2 Sulfatase WD40 PF00400.32 KFO96202.1 - 4.5e-05 24.1 0.9 1.4 9.9 0.1 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat RVT_1 PF00078.27 KFO96202.1 - 0.00037 20.1 0.0 0.00057 19.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ANAPC4_WD40 PF12894.7 KFO96202.1 - 0.14 12.5 0.0 19 5.6 0.0 3.7 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 KFO96204.1 - 1.6e-66 220.0 0.0 2e-23 82.0 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFO96204.1 - 3.3e-11 42.9 0.0 1.1e-05 25.2 0.0 3.0 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 KFO96204.1 - 1.6e-07 31.3 0.2 0.33 11.1 0.0 4.3 3 1 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KFO96204.1 - 0.00013 21.9 0.4 0.11 12.6 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KFO96204.1 - 0.00014 22.2 0.1 4.9 7.4 0.0 3.3 2 1 0 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter Calcipressin PF04847.12 KFO96204.1 - 0.00028 20.7 0.0 0.1 12.4 0.0 2.6 3 0 0 3 3 3 1 Calcipressin RRM_3 PF08777.11 KFO96204.1 - 0.00046 20.2 0.0 0.97 9.5 0.0 3.1 2 1 1 3 3 3 1 RNA binding motif RRM_5 PF13893.6 KFO96204.1 - 0.0013 18.4 0.0 5.2 6.7 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 KFO96204.1 - 0.0028 17.6 0.2 0.16 12.0 0.2 3.1 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DbpA PF03880.15 KFO96204.1 - 0.0037 17.2 0.0 0.94 9.5 0.0 3.2 3 0 0 3 3 3 1 DbpA RNA binding domain XOO_2897-deam PF14440.6 KFO96204.1 - 0.08 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase Cas_Cas2CT1978 PF09707.10 KFO96204.1 - 0.13 12.4 0.0 12 6.1 0.0 2.8 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_Cas2CT1978) Prenylcys_lyase PF07156.14 KFO96205.1 - 1.6e-156 521.0 0.0 2e-156 520.7 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 KFO96205.1 - 1.1e-05 25.0 0.0 2.6e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFO96205.1 - 0.048 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain LSM PF01423.22 KFO96206.1 - 5.7e-21 74.0 0.1 6.6e-21 73.8 0.1 1.0 1 0 0 1 1 1 1 LSM domain LRR_8 PF13855.6 KFO96208.1 - 1.2e-79 262.0 65.8 1.5e-15 56.7 1.0 5.5 1 1 5 7 7 7 7 Leucine rich repeat LRR_5 PF13306.6 KFO96208.1 - 3.5e-24 85.2 1.7 9.4e-10 38.5 0.0 2.6 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFO96208.1 - 9.1e-20 70.4 38.6 2.1e-06 27.9 4.3 6.7 2 2 6 9 9 9 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFO96208.1 - 2.5e-12 46.7 8.2 9.4e-05 22.0 0.4 3.9 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 KFO96208.1 - 1.6e-10 40.0 32.1 0.62 10.8 0.4 10.5 10 1 0 10 10 10 3 Leucine Rich Repeat LRR_6 PF13516.6 KFO96208.1 - 3e-05 23.7 31.5 0.56 10.4 0.4 8.6 9 0 0 9 9 9 4 Leucine Rich repeat LRRNT PF01462.18 KFO96208.1 - 0.025 14.2 3.7 0.04 13.6 1.9 2.2 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain LSR PF05624.14 KFO96208.1 - 5 7.2 7.2 0.33 11.0 1.6 1.9 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) Amidohydro_1 PF01979.20 KFO96209.1 - 5.2e-51 174.0 0.0 6.6e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFO96209.1 - 1.8e-12 47.5 0.5 1.6e-07 31.2 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family BNIP3 PF06553.12 KFO96210.1 - 2.1e-85 285.3 2.5 2.4e-85 285.2 2.5 1.0 1 0 0 1 1 1 1 BNIP3 DUF3319 PF11782.8 KFO96210.1 - 0.027 14.4 0.1 0.047 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3319) WD40 PF00400.32 KFO96211.1 - 2e-10 41.0 2.2 2.8 9.0 0.1 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO96211.1 - 1.9e-05 24.9 0.1 1.4 9.2 0.0 4.5 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Y_phosphatase2 PF03162.13 KFO96211.1 - 0.038 13.6 0.5 1.2 8.7 0.1 2.6 2 0 0 2 2 2 0 Tyrosine phosphatase family COE1_DBD PF16422.5 KFO96212.1 - 5.2e-133 441.6 4.2 6.7e-133 441.3 4.2 1.1 1 0 0 1 1 1 1 Transcription factor COE1 DNA-binding domain COE1_HLH PF16423.5 KFO96212.1 - 1.4e-34 117.5 2.0 7.9e-28 95.9 0.3 2.5 2 0 0 2 2 2 2 Transcription factor COE1 helix-loop-helix domain TIG PF01833.24 KFO96212.1 - 7.9e-12 45.1 0.1 7.9e-12 45.1 0.1 2.2 2 0 0 2 2 2 1 IPT/TIG domain PP1_bind PF15276.6 KFO96213.1 - 1.8e-17 63.4 0.1 2.2e-17 63.1 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 1 binding Pentapeptide PF00805.22 KFO96214.1 - 1.2e-37 127.1 23.6 1.3e-12 47.1 1.9 4.6 2 2 1 4 4 4 4 Pentapeptide repeats (8 copies) BTB_2 PF02214.22 KFO96214.1 - 1.1e-20 73.7 0.0 1.9e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Pentapeptide_4 PF13599.6 KFO96214.1 - 3.6e-20 71.9 0.3 4.8e-07 29.9 0.0 3.2 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 KFO96214.1 - 3e-14 52.9 0.0 8.8e-06 25.8 0.0 4.4 1 1 0 3 3 3 3 Pentapeptide repeats (9 copies) KHA PF11834.8 KFO96214.1 - 1.6e-13 50.5 0.1 2.9e-13 49.7 0.1 1.4 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel BTB_3 PF16017.5 KFO96214.1 - 2.8e-05 24.2 0.0 5.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KFO96214.1 - 5.7e-05 23.3 0.0 0.00013 22.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain GnRH PF00446.17 KFO96215.1 - 0.00083 19.5 5.2 0.0016 18.6 5.2 1.5 1 0 0 1 1 1 1 Gonadotropin-releasing hormone DHR-2 PF06920.13 KFO96216.1 - 5.9e-78 262.8 3.9 6.9e-78 262.6 3.9 1.0 1 0 0 1 1 1 1 Dock homology region 2 DUF1160 PF06648.11 KFO96216.1 - 0.015 15.3 0.0 0.038 14.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) CotJB PF12652.7 KFO96216.1 - 0.15 12.3 0.8 9.1 6.6 0.0 2.9 3 0 0 3 3 3 0 CotJB protein DOCK-C2 PF14429.6 KFO96218.1 - 3.3e-36 124.9 0.1 5.8e-36 124.1 0.0 1.4 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DOCK_N PF16172.5 KFO96218.1 - 1.5e-11 43.8 0.0 2e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 DOCK N-terminus IRK_C PF17655.1 KFO96218.1 - 0.054 13.1 0.1 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 Inward rectifier potassium channel C-terminal domain Filament PF00038.21 KFO96219.1 - 1.1e-109 366.9 49.4 1.1e-109 366.9 49.4 2.8 3 0 0 3 3 3 1 Intermediate filament protein Filament_head PF04732.14 KFO96219.1 - 2.8e-14 53.8 15.0 2.8e-14 53.8 15.0 1.9 2 0 0 2 2 2 1 Intermediate filament head (DNA binding) region DUF1664 PF07889.12 KFO96219.1 - 0.0017 18.4 2.9 0.0017 18.4 2.9 4.6 4 1 1 5 5 5 3 Protein of unknown function (DUF1664) TolA_bind_tri PF16331.5 KFO96219.1 - 0.063 13.4 39.4 1.6 8.8 5.3 5.4 3 2 2 5 5 5 0 TolA binding protein trimerisation NPV_P10 PF05531.12 KFO96219.1 - 0.078 13.4 0.5 0.078 13.4 0.5 4.1 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Lectin_N PF03954.14 KFO96219.1 - 0.66 9.7 10.4 4.1 7.2 1.2 3.9 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Spc29 PF17082.5 KFO96219.1 - 1.1 9.1 17.4 0.065 13.1 5.7 2.8 1 1 1 2 2 2 0 Spindle Pole Component 29 Baculo_PEP_C PF04513.12 KFO96219.1 - 3.3 7.7 13.7 10 6.2 1.2 3.9 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reprolysin PF01421.19 KFO96220.1 - 7.1e-67 225.2 0.1 7.1e-67 225.2 0.1 1.7 2 1 0 2 2 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 KFO96220.1 - 3.9e-24 85.5 0.1 6e-24 84.9 0.1 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_5 PF13688.6 KFO96220.1 - 3.2e-20 73.1 2.9 9.1e-20 71.6 0.0 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12 Disintegrin PF00200.23 KFO96220.1 - 1.2e-19 70.9 31.6 1.2e-19 70.9 31.6 3.0 3 0 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 KFO96220.1 - 1.2e-15 58.1 0.0 2.1e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFO96220.1 - 6.9e-15 55.2 0.0 1.3e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFO96220.1 - 1e-12 48.3 0.0 2.5e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFO96220.1 - 0.0039 17.1 0.0 0.005 16.7 0.0 1.2 1 0 0 1 1 1 1 Matrixin Astacin PF01400.24 KFO96220.1 - 0.023 14.3 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) DUF3810 PF12725.7 KFO96220.1 - 0.038 13.4 0.4 0.038 13.4 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Peptidase_M43 PF05572.13 KFO96220.1 - 0.082 12.8 0.0 0.27 11.1 0.0 1.9 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Peptidase_M66 PF10462.9 KFO96220.1 - 0.12 11.3 0.1 0.2 10.6 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 DUF4953 PF16313.5 KFO96220.1 - 0.19 10.9 0.1 0.36 10.0 0.1 1.3 1 0 0 1 1 1 0 Met-zincin Peptidase_M54 PF07998.11 KFO96220.1 - 0.74 9.8 2.8 0.42 10.6 0.3 1.8 2 0 0 2 2 2 0 Peptidase family M54 Stanniocalcin PF03298.13 KFO96221.1 - 1.4e-100 334.7 5.8 1.6e-100 334.5 5.8 1.0 1 0 0 1 1 1 1 Stanniocalcin family Homeodomain PF00046.29 KFO96222.1 - 2.2e-21 75.4 4.1 2.5e-21 75.3 4.1 1.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO96222.1 - 0.0038 17.1 0.1 0.0056 16.5 0.1 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 KFO96222.1 - 0.028 13.9 0.2 0.034 13.6 0.2 1.2 1 1 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez YdaS_antitoxin PF15943.5 KFO96222.1 - 0.063 13.2 0.0 0.077 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Mito_carr PF00153.27 KFO96223.1 - 2.8e-53 177.8 3.5 4.1e-21 74.7 0.4 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFO96223.1 - 0.15 11.2 2.0 0.28 10.3 0.5 2.1 1 1 1 2 2 2 0 Gammaproteobacterial serine protease GDA1_CD39 PF01150.17 KFO96224.1 - 1.6e-95 320.3 0.0 2.1e-95 319.9 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Adhesin_E PF16747.5 KFO96224.1 - 0.11 12.5 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Surface-adhesin protein E Lysyl_oxidase PF01186.17 KFO96225.1 - 1e-84 283.3 2.1 1.9e-84 282.4 2.1 1.5 1 0 0 1 1 1 1 Lysyl oxidase SRCR PF00530.18 KFO96225.1 - 1.3e-84 279.2 40.8 6.4e-29 100.4 2.8 5.3 5 0 0 5 5 5 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFO96225.1 - 1.2e-22 80.2 13.9 3.4e-05 24.3 0.3 4.6 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFO96225.1 - 3e-15 56.7 2.9 0.0044 17.5 0.0 4.8 4 0 0 4 4 4 4 Hepsin, SRCR domain R3H PF01424.22 KFO96226.1 - 3.2e-14 52.7 0.1 6.5e-14 51.7 0.1 1.6 1 0 0 1 1 1 1 R3H domain NCBP3 PF10309.9 KFO96226.1 - 1.4e-05 24.8 0.0 2.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RgpF PF05045.12 KFO96226.1 - 0.13 11.0 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Rhamnan synthesis protein F Snf7 PF03357.21 KFO96227.1 - 1.3e-21 77.0 8.3 1.3e-21 77.0 8.3 2.1 2 0 0 2 2 2 1 Snf7 PspA_IM30 PF04012.12 KFO96227.1 - 1.2e-05 25.0 0.6 1.2e-05 25.0 0.6 2.2 2 0 0 2 2 2 1 PspA/IM30 family Fez1 PF06818.15 KFO96227.1 - 0.019 15.5 4.6 0.019 15.5 4.6 2.2 1 1 0 2 2 2 0 Fez1 DUF763 PF05559.11 KFO96227.1 - 0.039 13.1 1.6 0.067 12.4 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Allexi_40kDa PF05549.11 KFO96227.1 - 0.05 13.1 2.9 1.3 8.5 0.1 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein AAA_27 PF13514.6 KFO96227.1 - 0.12 12.0 0.6 0.45 10.1 0.1 2.0 1 1 1 2 2 2 0 AAA domain Citrate_synt PF00285.21 KFO96227.1 - 0.18 10.8 0.4 2.3 7.2 0.2 2.0 1 1 1 2 2 2 0 Citrate synthase, C-terminal domain Fmp27_WPPW PF10359.9 KFO96227.1 - 0.64 8.8 4.8 0.71 8.7 3.8 1.4 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TMPIT PF07851.13 KFO96227.1 - 3.6 6.7 4.7 5 6.3 3.7 1.7 1 1 0 1 1 1 0 TMPIT-like protein LPP PF04728.13 KFO96227.1 - 5.9 7.4 8.5 4 7.9 0.3 3.2 3 1 0 3 3 3 0 Lipoprotein leucine-zipper Snapin_Pallidin PF14712.6 KFO96227.1 - 6.8 7.2 12.3 0.78 10.2 2.5 3.3 2 1 2 4 4 4 0 Snapin/Pallidin Death PF00531.22 KFO96228.1 - 4.8e-15 55.5 0.0 7.3e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Death domain TNFR_c6 PF00020.18 KFO96228.1 - 7.2e-12 45.5 34.0 1.7e-07 31.5 10.5 4.0 3 1 1 4 4 4 2 TNFR/NGFR cysteine-rich region Ras PF00071.22 KFO96229.1 - 3.2e-25 88.6 0.0 6.5e-25 87.6 0.0 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFO96229.1 - 1.8e-10 41.1 0.0 3.5e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase PI-PLC-X PF00388.19 KFO96232.1 - 2.2e-64 215.4 0.1 2.2e-64 215.4 0.1 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain SH2 PF00017.24 KFO96232.1 - 1.6e-46 156.3 0.8 1.8e-23 82.4 0.1 2.6 2 0 0 2 2 2 2 SH2 domain SH3_1 PF00018.28 KFO96232.1 - 6e-16 57.8 0.6 1.9e-15 56.2 0.6 1.9 1 0 0 1 1 1 1 SH3 domain C2 PF00168.30 KFO96232.1 - 1.5e-14 54.1 0.0 3.1e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain SH3_9 PF14604.6 KFO96232.1 - 2.7e-10 39.9 0.2 2.7e-10 39.9 0.2 2.1 2 0 0 2 2 2 1 Variant SH3 domain PH PF00169.29 KFO96232.1 - 5.5e-10 39.7 0.1 7.1e-05 23.3 0.0 2.9 2 0 0 2 2 2 2 PH domain SH3_2 PF07653.17 KFO96232.1 - 2.2e-07 30.5 0.1 6.3e-07 29.0 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain PI-PLC-Y PF00387.19 KFO96232.1 - 6.5e-05 23.2 0.0 0.00072 19.9 0.0 2.4 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain GDPD PF03009.17 KFO96232.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family UCH PF00443.29 KFO96233.1 - 2.1e-06 27.4 0.2 1.3e-05 24.9 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase NAPRTase_C PF17956.1 KFO96234.1 - 4.8e-30 104.2 0.0 8.3e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase_N PF17767.1 KFO96234.1 - 2.6e-10 40.7 0.0 1e-09 38.9 0.0 1.9 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase PF04095.16 KFO96234.1 - 0.00015 21.5 0.0 0.055 13.1 0.0 2.3 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family EF1_GNE PF00736.19 KFO96235.1 - 2.2e-37 127.1 1.1 4.6e-37 126.1 1.1 1.6 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KFO96235.1 - 1.1e-12 48.1 8.4 1.1e-12 48.1 8.4 2.2 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region Lzipper-MIP1 PF14389.6 KFO96235.1 - 0.0048 17.2 0.1 1.7 9.0 0.0 3.1 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 TSC22 PF01166.18 KFO96235.1 - 0.014 15.7 0.7 0.044 14.1 0.7 1.9 1 0 0 1 1 1 0 TSC-22/dip/bun family JIP_LZII PF16471.5 KFO96235.1 - 0.02 15.0 1.0 0.05 13.8 1.0 1.6 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II Striatin PF08232.12 KFO96235.1 - 0.029 15.0 1.4 0.029 15.0 1.4 2.2 2 1 0 2 2 2 0 Striatin family CCD48 PF15799.5 KFO96235.1 - 0.031 12.6 1.6 0.06 11.7 1.6 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 48 Sigma70_ner PF04546.13 KFO96235.1 - 0.13 12.1 3.1 0.24 11.2 3.1 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region WD40_alt PF14077.6 KFO96235.1 - 0.17 11.8 0.5 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 Alternative WD40 repeat motif DDE_1 PF03184.19 KFO96236.1 - 2.1e-19 69.8 0.0 3.7e-18 65.8 0.0 2.4 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFO96236.1 - 1.3e-17 63.6 0.4 2.5e-17 62.7 0.4 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFO96236.1 - 2.1e-08 33.7 0.0 3.8e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 KFO96236.1 - 2.1e-05 24.5 0.4 0.00023 21.2 0.1 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 KFO96236.1 - 0.00019 21.7 0.2 0.00055 20.2 0.2 1.8 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 KFO96236.1 - 0.0013 18.4 0.7 0.0091 15.8 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain P5CR_dimer PF14748.6 KFO96237.1 - 7.2e-36 122.6 2.1 1.2e-35 121.8 2.1 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KFO96237.1 - 4.8e-07 30.3 0.1 2.9e-06 27.7 0.0 2.3 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 KFO96237.1 - 0.011 15.7 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Epimerase PF01370.21 KFO96238.1 - 1.8e-46 158.6 0.0 2.3e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFO96238.1 - 1.6e-07 31.1 0.0 1.9e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KFO96238.1 - 0.077 12.1 0.0 0.24 10.5 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Arrestin_N PF00339.29 KFO96239.1 - 2.7e-35 121.6 0.1 1.1e-33 116.4 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KFO96239.1 - 4.7e-24 85.4 0.0 4.5e-20 72.5 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.15 KFO96239.1 - 0.0048 15.9 0.0 0.027 13.5 0.0 2.1 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 BTB PF00651.31 KFO96240.1 - 7.7e-25 87.3 0.0 9e-25 87.1 0.0 1.0 1 0 0 1 1 1 1 BTB/POZ domain DUF3342 PF11822.8 KFO96240.1 - 0.065 13.4 0.0 0.13 12.5 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3342) zf-H2C2_2 PF13465.6 KFO96241.1 - 3.3e-13 49.4 17.4 1.5e-07 31.5 5.3 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFO96241.1 - 5e-09 36.1 24.5 1.2e-05 25.5 6.0 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO96241.1 - 1.5e-05 25.4 21.0 0.00049 20.7 4.4 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO96241.1 - 0.00026 21.2 2.1 0.00026 21.2 2.1 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFO96241.1 - 0.0012 18.7 3.4 0.0012 18.7 3.4 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KFO96241.1 - 0.0082 16.5 15.4 0.01 16.2 2.0 3.4 3 1 0 3 3 3 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFO96241.1 - 0.012 15.9 7.8 0.012 15.9 7.8 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Elf1 PF05129.13 KFO96241.1 - 0.014 15.4 4.2 0.021 14.9 4.2 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-AN1 PF01428.16 KFO96241.1 - 0.028 14.6 10.9 0.066 13.4 2.8 2.4 1 1 1 2 2 2 0 AN1-like Zinc finger Rtf2 PF04641.12 KFO96241.1 - 0.03 13.7 3.1 0.046 13.1 0.1 1.9 1 1 1 2 2 2 0 Rtf2 RING-finger DUF2225 PF09986.9 KFO96241.1 - 0.032 13.9 0.5 0.032 13.9 0.5 2.4 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_9 PF16293.5 KFO96241.1 - 0.046 13.6 2.9 0.046 13.6 2.9 1.7 2 1 0 2 2 2 0 C2H2 type zinc-finger (1 copy) CpXC PF14353.6 KFO96241.1 - 0.072 13.1 0.4 0.072 13.1 0.4 1.8 1 1 1 2 2 2 0 CpXC protein Zn-C2H2_12 PF18112.1 KFO96241.1 - 0.081 13.4 4.5 0.081 13.4 4.5 3.6 3 1 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain NADH-G_4Fe-4S_3 PF10588.9 KFO96241.1 - 0.11 12.0 3.9 0.26 10.9 0.4 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Rad50_zn_hook PF04423.14 KFO96241.1 - 0.16 11.8 0.1 0.16 11.8 0.1 2.4 3 0 0 3 3 3 0 Rad50 zinc hook motif DUF2256 PF10013.9 KFO96241.1 - 0.19 11.9 4.7 1.1 9.4 0.1 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF4428 PF14471.6 KFO96241.1 - 0.23 11.4 5.3 1.4 8.9 4.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4428) zf-C2H2_2 PF12756.7 KFO96241.1 - 0.31 11.4 10.1 1.2 9.5 9.4 2.1 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) FYDLN_acid PF09538.10 KFO96241.1 - 0.45 11.2 2.5 0.86 10.3 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-C2HE PF16278.5 KFO96241.1 - 1.1 9.8 12.1 2.8 8.5 5.5 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger XPA_N PF01286.18 KFO96241.1 - 1.5 8.9 6.8 1.6 8.9 0.3 2.8 3 0 0 3 3 3 0 XPA protein N-terminal zf_UBZ PF18439.1 KFO96241.1 - 2.3 7.9 9.1 0.3 10.7 0.8 2.8 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-CCHC_2 PF13696.6 KFO96241.1 - 7.5 6.5 10.2 0.42 10.5 1.6 2.5 2 1 0 2 2 2 0 Zinc knuckle Ribosomal_S13 PF00416.22 KFO96242.1 - 0.018 15.4 0.1 0.02 15.3 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein S13/S18 Band_7 PF01145.25 KFO96243.1 - 8.4e-26 91.1 1.3 1.1e-25 90.6 1.3 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.8 KFO96243.1 - 0.0048 17.0 0.4 0.008 16.3 0.4 1.4 1 0 0 1 1 1 1 Mediator complex subunit 2 zf-C2H2 PF00096.26 KFO96244.1 - 2.3e-35 119.1 62.5 1.3e-05 25.4 1.5 9.5 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO96244.1 - 1.2e-27 95.0 69.3 1.4e-07 31.6 1.3 9.7 9 1 0 9 9 9 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFO96244.1 - 8.5e-26 88.4 62.0 9.7e-05 22.9 0.8 9.5 9 0 0 9 9 9 8 C2H2-type zinc finger zf-met PF12874.7 KFO96244.1 - 8.3e-12 45.1 44.0 0.0019 18.5 0.1 8.6 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFO96244.1 - 1.6e-09 37.8 45.0 0.046 14.0 0.0 8.4 9 0 0 9 9 9 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFO96244.1 - 6.2e-07 29.3 56.8 0.0095 15.9 0.2 9.3 9 0 0 9 9 9 6 C2H2-type zinc finger zf_UBZ PF18439.1 KFO96244.1 - 0.004 16.7 34.3 3.3 7.4 0.1 9.1 9 0 0 9 9 9 2 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 KFO96244.1 - 0.0066 16.2 33.9 0.12 12.2 0.7 7.6 8 0 0 8 8 8 3 zinc-finger C2H2-type zf-Di19 PF05605.12 KFO96244.1 - 0.0087 16.3 1.3 0.0087 16.3 1.3 5.2 4 2 1 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding BolA PF01722.18 KFO96244.1 - 0.01 16.1 9.2 0.7 10.2 0.1 4.0 3 1 1 4 4 4 0 BolA-like protein ADK_lid PF05191.14 KFO96244.1 - 0.017 15.1 0.5 0.017 15.1 0.5 5.9 5 1 1 6 6 6 0 Adenylate kinase, active site lid DUF3268 PF11672.8 KFO96244.1 - 0.04 14.3 17.8 1.3 9.4 0.4 4.2 2 1 2 4 4 4 0 zinc-finger-containing domain zf-C2H2_2 PF12756.7 KFO96244.1 - 0.042 14.2 49.9 0.6 10.5 1.9 7.2 1 1 6 7 7 7 0 C2H2 type zinc-finger (2 copies) zf_C2H2_13 PF18508.1 KFO96244.1 - 0.21 11.2 5.9 6.4 6.5 0.1 4.6 4 0 0 4 4 4 0 Zinc finger domain SDA1 PF05285.12 KFO96244.1 - 0.27 10.6 21.4 0.4 10.1 21.4 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KFO96244.1 - 0.3 10.4 23.3 0.44 9.8 23.3 1.1 1 0 0 1 1 1 0 BUD22 Zn-ribbon_8 PF09723.10 KFO96244.1 - 0.37 11.0 44.7 0.71 10.0 1.0 7.4 4 3 4 8 8 8 0 Zinc ribbon domain zf-C2H2_3rep PF18868.1 KFO96244.1 - 0.41 11.3 0.1 0.41 11.3 0.1 7.3 2 1 5 7 7 6 0 Zinc finger C2H2-type, 3 repeats zf-C2HC_2 PF13913.6 KFO96244.1 - 0.5 10.3 45.1 0.93 9.5 0.0 8.7 9 0 0 9 9 9 0 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 KFO96244.1 - 1.1 10.1 35.6 1.1 10.0 2.1 5.2 1 1 2 4 4 4 0 zinc-ribbon family DUF2502 PF10697.9 KFO96244.1 - 1.3 9.4 0.0 1.3 9.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2502) Put_Phosphatase PF06888.12 KFO96245.1 - 8.3e-98 326.5 0.0 9.2e-98 326.3 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 KFO96245.1 - 1.8e-08 35.0 0.0 3.2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFO96245.1 - 0.0016 18.8 0.0 0.2 11.9 0.0 2.5 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase PNK3P PF08645.11 KFO96245.1 - 0.0058 16.4 0.3 0.25 11.0 0.3 2.4 1 1 0 1 1 1 1 Polynucleotide kinase 3 phosphatase HAD_2 PF13419.6 KFO96245.1 - 0.029 14.4 0.2 2.4 8.2 0.2 2.8 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase G-gamma PF00631.22 KFO96246.1 - 6.7e-19 67.7 0.1 7.2e-19 67.6 0.1 1.0 1 0 0 1 1 1 1 GGL domain Bacillus_HBL PF05791.11 KFO96246.1 - 0.016 15.0 0.7 0.018 14.8 0.7 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Cwf_Cwc_15 PF04889.12 KFO96246.1 - 0.14 11.9 2.2 0.14 11.9 2.2 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein KH_1 PF00013.29 KFO96247.1 - 2.3e-58 193.9 12.1 2.3e-14 52.9 0.1 4.5 4 0 0 4 4 4 4 KH domain KH_2 PF07650.17 KFO96247.1 - 6.2e-19 67.6 3.3 0.0012 18.7 0.1 4.6 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 KFO96247.1 - 3.2e-16 58.9 1.0 0.0044 16.9 0.0 5.1 5 0 0 5 5 5 4 KH domain KH_5 PF13184.6 KFO96247.1 - 1.2e-08 34.9 3.9 0.37 10.9 0.1 4.4 4 0 0 4 4 4 3 NusA-like KH domain RRM_1 PF00076.22 KFO96247.1 - 2.7e-08 33.5 0.0 5.7e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MOEP19 PF16005.5 KFO96247.1 - 9.7e-08 31.9 0.2 0.054 13.5 0.0 4.3 4 0 0 4 4 4 2 KH-like RNA-binding domain RRM_occluded PF16842.5 KFO96247.1 - 0.01 15.7 0.0 0.049 13.5 0.0 2.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_5 PF13893.6 KFO96247.1 - 0.027 14.1 0.2 0.092 12.3 0.1 1.9 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hormone_2 PF00123.20 KFO96248.1 - 1.6e-09 37.5 2.7 1.8e-07 30.9 0.1 3.0 3 0 0 3 3 3 2 Peptide hormone EAP30 PF04157.16 KFO96249.1 - 1.2e-73 247.3 0.1 1.4e-73 247.1 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family ZapD PF07072.11 KFO96249.1 - 0.025 14.4 1.7 9.8 5.9 0.0 3.0 3 0 0 3 3 3 0 Cell division protein Plasmid_RAQPRD PF09686.10 KFO96249.1 - 0.056 13.7 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) EutK_C PF16365.5 KFO96249.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilization protein EutK C-terminus TrmB PF01978.19 KFO96249.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Phage_Mu_Gam PF07352.12 KFO96249.1 - 0.91 9.4 5.3 0.28 11.1 0.7 2.2 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein ATP-synt_C PF00137.21 KFO96250.1 - 4.5e-12 46.1 12.4 5.6e-12 45.8 12.4 1.1 1 0 0 1 1 1 1 ATP synthase subunit C SKICH PF17751.1 KFO96251.1 - 9.9e-34 116.0 0.6 2.8e-33 114.5 0.6 1.8 1 0 0 1 1 1 1 SKICH domain Zn-C2H2_12 PF18112.1 KFO96251.1 - 2.2e-11 44.0 14.5 7.4e-08 32.7 0.8 2.8 2 0 0 2 2 2 2 Autophagy receptor zinc finger-C2H2 domain GOLGA2L5 PF15070.6 KFO96251.1 - 1.2e-06 27.5 36.4 1.2e-06 27.5 36.4 1.5 2 0 0 2 2 2 1 Putative golgin subfamily A member 2-like protein 5 KASH_CCD PF14662.6 KFO96251.1 - 3.2e-06 27.1 36.4 3.2e-06 27.1 36.4 2.4 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH zf-C2H2_4 PF13894.6 KFO96251.1 - 0.00068 20.3 1.5 1.2 10.1 0.2 3.3 2 0 0 2 2 2 1 C2H2-type zinc finger Noelin-1 PF12308.8 KFO96251.1 - 0.00072 19.5 4.7 0.00072 19.5 4.7 3.2 1 1 2 3 3 3 1 Neurogenesis glycoprotein ZapB PF06005.12 KFO96251.1 - 0.002 18.5 56.3 0.091 13.2 6.2 4.5 2 1 2 4 4 4 3 Cell division protein ZapB bZIP_1 PF00170.21 KFO96251.1 - 0.01 15.9 3.9 0.01 15.9 3.9 6.2 3 1 3 6 6 6 0 bZIP transcription factor DUF3450 PF11932.8 KFO96251.1 - 0.012 14.9 14.2 0.012 14.9 14.2 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF3450) WD40_alt PF14077.6 KFO96251.1 - 0.11 12.3 15.9 0.5 10.3 3.7 3.7 2 1 1 3 3 3 0 Alternative WD40 repeat motif UBZ_FAAP20 PF15750.5 KFO96251.1 - 0.12 12.3 4.7 0.58 10.1 0.6 3.0 2 1 1 3 3 3 0 Ubiquitin-binding zinc-finger TraF_2 PF13729.6 KFO96251.1 - 0.24 10.7 6.2 3.4 6.9 1.7 2.8 2 1 1 3 3 3 0 F plasmid transfer operon, TraF, protein NPV_P10 PF05531.12 KFO96251.1 - 0.38 11.3 17.5 5.4 7.6 7.2 3.7 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Jnk-SapK_ap_N PF09744.9 KFO96251.1 - 0.4 10.9 52.6 0.6 10.3 29.8 3.1 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 EMP24_GP25L PF01105.24 KFO96251.1 - 0.5 10.3 23.8 2.6e+02 1.4 19.0 4.1 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD GAS PF13851.6 KFO96251.1 - 0.5 9.7 53.4 0.056 12.8 24.8 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding zf-C2H2_6 PF13912.6 KFO96251.1 - 0.6 10.2 3.0 15 5.7 0.8 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger HOOK PF05622.12 KFO96251.1 - 0.9 7.6 47.2 2.3 6.3 47.1 1.5 1 1 0 1 1 1 0 HOOK protein DUF1664 PF07889.12 KFO96251.1 - 1.2 9.1 20.1 3.7 7.6 5.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.15 KFO96251.1 - 1.5 8.7 44.2 0.6 9.9 6.2 6.3 3 2 4 7 7 7 0 Septum formation initiator Prok-RING_1 PF14446.6 KFO96251.1 - 1.6 8.7 4.5 6.2 6.8 0.4 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C2H2 PF00096.26 KFO96251.1 - 1.7 9.2 5.9 38 5.0 0.3 3.5 2 1 0 2 2 2 0 Zinc finger, C2H2 type CALCOCO1 PF07888.11 KFO96251.1 - 4.8 5.9 43.9 2 7.2 21.7 2.1 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like JIP_LZII PF16471.5 KFO96251.1 - 5.2 7.3 40.2 1.3 9.2 5.0 5.0 4 1 1 5 5 5 0 JNK-interacting protein leucine zipper II zf-Di19 PF05605.12 KFO96251.1 - 8.7 6.7 8.2 7.6 6.9 5.0 2.7 2 1 0 2 2 1 0 Drought induced 19 protein (Di19), zinc-binding DUF5082 PF16888.5 KFO96251.1 - 9.2 6.6 31.3 0.034 14.4 18.4 2.7 2 1 1 3 3 2 0 Domain of unknown function (DUF5082) EzrA PF06160.12 KFO96251.1 - 9.2 4.3 39.9 4.7e+02 -1.3 39.9 2.1 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA TPR_MLP1_2 PF07926.12 KFO96251.1 - 9.5 6.3 49.4 1.1 9.3 6.2 4.2 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein Homeodomain PF00046.29 KFO96252.1 - 2.7e-19 68.7 5.3 3.2e-19 68.5 5.3 1.1 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO96252.1 - 0.00033 20.5 4.0 0.00044 20.1 4.0 1.4 1 1 0 1 1 1 1 Homeobox KN domain DUF1510 PF07423.11 KFO96252.1 - 0.002 18.2 0.1 0.0023 18.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1510) CI-B14_5a PF07347.12 KFO96252.1 - 0.0088 15.9 0.3 0.0096 15.8 0.3 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Hox9_act PF04617.13 KFO96253.1 - 4.9e-59 200.2 4.6 7.3e-59 199.6 4.6 1.3 1 0 0 1 1 1 1 Hox9 activation region Homeodomain PF00046.29 KFO96253.1 - 6.6e-21 73.9 6.3 1.1e-20 73.2 6.3 1.4 1 0 0 1 1 1 1 Homeodomain HTH_23 PF13384.6 KFO96253.1 - 0.0037 17.0 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain Homeobox_KN PF05920.11 KFO96253.1 - 0.065 13.1 0.3 0.15 12.0 0.3 1.6 1 0 0 1 1 1 0 Homeobox KN domain Homeodomain PF00046.29 KFO96254.1 - 6.2e-22 77.2 8.1 9.1e-22 76.7 8.1 1.3 1 0 0 1 1 1 1 Homeodomain DUF2209 PF09974.9 KFO96254.1 - 0.05 13.9 0.1 0.068 13.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Homeodomain PF00046.29 KFO96255.1 - 5.5e-22 77.4 8.7 8.5e-22 76.8 8.7 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO96255.1 - 0.14 12.1 0.9 0.33 10.9 0.9 1.7 1 0 0 1 1 1 0 Homeobox KN domain DUF2209 PF09974.9 KFO96255.1 - 0.18 12.1 0.1 0.26 11.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) DUF4074 PF13293.6 KFO96257.1 - 8e-35 119.0 9.8 8e-35 119.0 9.8 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF4074) Homeodomain PF00046.29 KFO96257.1 - 2.2e-14 53.0 5.1 2.2e-14 53.0 5.1 1.9 2 0 0 2 2 2 1 Homeodomain Homeodomain PF00046.29 KFO96258.1 - 2.7e-22 78.4 7.2 3.6e-22 78.0 7.2 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO96258.1 - 0.053 13.4 4.0 0.061 13.2 0.6 2.2 2 0 0 2 2 2 0 Homeobox KN domain Mlo PF03094.15 KFO96258.1 - 1.9 6.8 4.2 1.4 7.2 0.3 1.9 1 1 1 2 2 2 0 Mlo family PX PF00787.24 KFO96259.1 - 3.6e-26 91.4 0.4 4.2e-26 91.1 0.4 1.1 1 0 0 1 1 1 1 PX domain PaO PF08417.12 KFO96259.1 - 0.089 12.9 0.0 0.14 12.3 0.0 1.4 1 1 0 1 1 1 0 Pheophorbide a oxygenase Chromo_shadow PF01393.19 KFO96260.1 - 7.9e-34 115.5 0.1 6.8e-31 106.1 0.0 2.5 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 KFO96260.1 - 7.1e-23 80.3 0.4 1.6e-18 66.3 0.4 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 KFO96260.1 - 0.0013 18.9 0.2 0.0094 16.1 0.2 2.0 2 0 0 2 2 2 1 Polycomb-like MTF2 factor 2 CDC45 PF02724.14 KFO96260.1 - 0.82 7.9 5.8 0.88 7.8 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein ELM2 PF01448.24 KFO96260.1 - 7.4 7.4 7.0 1.6 9.6 0.8 2.4 2 1 0 2 2 2 0 ELM2 domain Ribosomal_L22 PF00237.19 KFO96261.1 - 2.3e-44 149.8 0.0 3.6e-44 149.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF4512 PF14975.6 KFO96262.1 - 2.4e-17 63.5 2.6 2.5e-17 63.4 2.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4512) DUF5381 PF17353.2 KFO96262.1 - 0.17 11.6 0.0 0.2 11.4 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5381) Dymeclin PF09742.9 KFO96263.1 - 1.4e-09 37.0 0.1 1.4e-09 37.0 0.1 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Cadherin PF00028.17 KFO96264.1 - 1.6e-50 169.5 0.0 5.6e-20 71.6 0.0 4.1 4 0 0 4 4 4 4 Cadherin domain Cadherin_3 PF16184.5 KFO96264.1 - 7.3e-06 26.0 0.3 0.053 13.5 0.0 3.6 4 0 0 4 4 4 2 Cadherin-like Cadherin_2 PF08266.12 KFO96264.1 - 0.0081 16.0 0.0 0.26 11.1 0.0 2.7 2 0 0 2 2 2 1 Cadherin-like Cadherin_4 PF17803.1 KFO96264.1 - 0.027 15.1 5.8 3.4 8.4 0.2 3.4 3 0 0 3 3 3 0 Bacterial cadherin-like domain Cadherin-like PF12733.7 KFO96264.1 - 0.32 11.6 3.1 2.1 8.9 0.1 3.0 2 1 0 3 3 3 0 Cadherin-like beta sandwich domain E1-E2_ATPase PF00122.20 KFO96266.1 - 9.7e-13 48.0 2.1 5e-12 45.7 0.4 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 KFO96266.1 - 6.3e-11 41.8 0.0 1.1e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus MARVEL PF01284.23 KFO96266.1 - 0.063 13.3 0.6 0.076 13.0 0.6 1.1 1 0 0 1 1 1 0 Membrane-associating domain BCCT PF02028.17 KFO96266.1 - 0.092 11.2 0.1 0.11 10.9 0.1 1.0 1 0 0 1 1 1 0 BCCT, betaine/carnitine/choline family transporter E1-E2_ATPase PF00122.20 KFO96267.1 - 3.6e-24 85.3 0.5 4.2e-24 85.1 0.5 1.0 1 0 0 1 1 1 1 E1-E2 ATPase Tektin PF03148.14 KFO96268.1 - 1.3e-142 475.1 29.7 1.5e-142 474.9 29.7 1.0 1 0 0 1 1 1 1 Tektin family PKHD_C PF18331.1 KFO96268.1 - 0.0031 17.5 0.3 0.052 13.6 0.2 2.7 2 0 0 2 2 2 1 PKHD-type hydroxylase C-terminal domain Sin3_corepress PF08295.12 KFO96268.1 - 0.091 12.8 1.9 1.2 9.3 0.3 3.0 2 0 0 2 2 2 0 Sin3 family co-repressor Dna2 PF08696.11 KFO96268.1 - 1.3 8.8 5.2 3 7.6 1.3 2.9 2 1 1 3 3 3 0 DNA replication factor Dna2 Caskin-tail PF16632.5 KFO96268.1 - 3 8.3 7.6 3.3 8.2 0.0 3.5 4 0 0 4 4 4 0 C-terminal region of Caskin CENP-F_leu_zip PF10473.9 KFO96268.1 - 8.9 6.3 33.1 1.7 8.7 0.8 4.4 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 dUTPase PF00692.19 KFO96269.1 - 1.8e-16 60.0 0.0 2.3e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 dUTPase RVP PF00077.20 KFO96269.1 - 0.026 14.8 0.0 0.051 13.9 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Frtz PF11768.8 KFO96271.1 - 0.029 12.7 0.0 0.052 11.9 0.0 1.6 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Ala_racemase_N PF01168.20 KFO96272.1 - 1.5e-05 24.8 0.0 1.5e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain SET PF00856.28 KFO96273.1 - 1.9e-18 67.4 0.1 1.9e-18 67.4 0.1 4.3 4 2 0 5 5 5 1 SET domain AWS PF17907.1 KFO96273.1 - 1.6e-12 47.2 5.1 4.2e-12 45.9 5.1 1.8 1 0 0 1 1 1 1 AWS domain SRI PF08236.11 KFO96273.1 - 5.4e-12 45.7 1.4 2.7e-11 43.5 1.4 2.3 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain WW PF00397.26 KFO96273.1 - 1.7e-11 44.0 3.6 6.5e-11 42.1 3.6 2.1 1 0 0 1 1 1 1 WW domain Kinesin PF00225.23 KFO96274.1 - 8.8e-76 255.0 0.2 2.3e-75 253.6 0.2 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFO96274.1 - 3.7e-18 65.9 0.0 1e-17 64.4 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding HTH_48 PF17906.1 KFO96274.1 - 0.0026 17.9 0.0 2.2 8.5 0.0 2.7 2 0 0 2 2 2 2 HTH domain in Mos1 transposase zf-C4H2 PF10146.9 KFO96274.1 - 0.0029 17.9 7.7 0.0092 16.3 7.7 1.9 1 0 0 1 1 1 1 Zinc finger-containing protein AAA_22 PF13401.6 KFO96274.1 - 0.0068 16.7 4.8 0.014 15.7 0.0 3.6 4 1 1 5 5 5 1 AAA domain AAA_16 PF13191.6 KFO96274.1 - 0.021 15.2 1.2 0.047 14.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 KFO96274.1 - 0.038 13.5 0.0 0.16 11.4 0.1 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 KFO96274.1 - 0.041 13.6 0.2 0.15 11.7 0.0 2.1 3 0 0 3 3 3 0 AAA domain DUF2408 PF10303.9 KFO96274.1 - 0.48 11.0 8.0 1.4 9.4 8.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) SKA2 PF16740.5 KFO96274.1 - 1.9 8.3 13.1 0.11 12.3 3.0 2.8 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Seryl_tRNA_N PF02403.22 KFO96274.1 - 2.7 8.3 10.7 6.9 6.9 3.0 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 KFO96274.1 - 3 6.6 18.8 0.24 10.2 13.9 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein PAP2 PF01569.21 KFO96275.1 - 7.4e-26 90.5 2.6 1.4e-25 89.7 1.6 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KFO96275.1 - 2.2e-05 24.9 1.5 2.2e-05 24.9 1.5 1.9 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2_3 PF14378.6 KFO96275.1 - 0.005 16.5 1.4 0.015 15.0 1.4 1.7 1 1 0 1 1 1 1 PAP2 superfamily Antimicrobial13 PF08108.11 KFO96275.1 - 0.24 11.5 1.1 0.96 9.6 0.1 2.3 2 0 0 2 2 2 0 Halocidin family Herpes_LMP1 PF05297.11 KFO96275.1 - 0.4 9.8 1.1 1.6 7.9 0.1 2.0 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Pkinase PF00069.25 KFO96276.1 - 2.9e-67 226.8 0.0 4.3e-67 226.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO96276.1 - 9.8e-37 126.6 0.0 1.7e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KFO96276.1 - 9.5e-16 58.3 0.4 5.5e-15 55.9 0.0 2.4 3 0 0 3 3 3 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 KFO96276.1 - 1.6e-06 27.6 0.0 2.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFO96276.1 - 0.00053 19.6 0.3 0.0021 17.7 0.2 1.9 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KFO96276.1 - 0.0017 17.8 0.4 0.0031 16.9 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFO96276.1 - 0.016 15.1 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFO96276.1 - 0.021 13.8 0.1 0.039 12.9 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain hSH3 PF14603.6 KFO96277.1 - 1.4e-14 54.3 0.0 2.7e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Helically-extended SH3 domain MACPF PF01823.19 KFO96278.1 - 3.8e-43 148.0 0.1 3e-42 145.1 0.0 2.0 2 0 0 2 2 2 1 MAC/Perforin domain Ldl_recept_a PF00057.18 KFO96278.1 - 1.9e-10 40.7 12.0 1.9e-10 40.7 12.0 2.6 1 1 0 1 1 1 1 Low-density lipoprotein receptor domain class A TSP_1 PF00090.19 KFO96278.1 - 0.00043 20.5 10.7 0.00043 20.5 10.7 3.9 4 1 0 4 4 4 2 Thrombospondin type 1 domain MACPF PF01823.19 KFO96279.1 - 2.8e-33 115.8 0.0 5e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 MAC/Perforin domain Ldl_recept_a PF00057.18 KFO96279.1 - 7.8e-09 35.6 10.6 3.6e-08 33.5 10.6 2.3 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A TSP_1 PF00090.19 KFO96279.1 - 3.6e-06 27.1 23.7 0.00027 21.1 6.3 3.6 3 0 0 3 3 3 2 Thrombospondin type 1 domain PID PF00640.23 KFO96280.1 - 2.5e-08 34.0 0.1 4.2e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Peptidase_M48 PF01435.18 KFO96281.1 - 3.7e-31 108.4 0.0 5.3e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Sulf_transp PF04143.14 KFO96281.1 - 0.01 15.4 0.2 0.019 14.5 0.2 1.4 1 0 0 1 1 1 0 Sulphur transport Peptidase_U49 PF10463.9 KFO96281.1 - 0.096 12.4 0.4 0.29 10.9 0.3 1.8 2 0 0 2 2 2 0 Peptidase U49 SWIRM PF04433.17 KFO96282.1 - 2.3e-21 75.9 0.2 8.1e-21 74.2 0.0 2.1 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.31 KFO96282.1 - 1.8e-12 47.2 0.2 4.9e-12 45.8 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain JAB PF01398.21 KFO96282.1 - 4.7e-12 45.9 0.0 1.2e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KFO96282.1 - 6.1e-09 35.7 0.0 1.7e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Myb_DNA-bind_6 PF13921.6 KFO96282.1 - 1.5e-05 25.1 0.3 4.6e-05 23.6 0.3 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain UPF0172 PF03665.13 KFO96282.1 - 0.0027 17.8 0.0 0.0077 16.3 0.0 1.8 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) Myb_DNA-bind_7 PF15963.5 KFO96282.1 - 0.075 12.9 0.2 0.38 10.7 0.1 2.3 2 0 0 2 2 2 0 Myb DNA-binding like Ank_2 PF12796.7 KFO96283.1 - 1.4e-82 272.4 39.8 9e-20 71.1 0.2 7.3 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFO96283.1 - 2.4e-74 244.8 15.5 5.9e-13 49.1 0.0 11.6 6 4 7 13 13 13 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFO96283.1 - 2.6e-63 209.3 21.5 1.7e-09 37.7 0.1 13.0 3 3 10 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFO96283.1 - 9.7e-63 200.7 21.3 0.00019 21.6 0.0 15.1 15 1 0 15 15 15 14 Ankyrin repeat Ank PF00023.30 KFO96283.1 - 3.1e-62 204.5 42.6 9.1e-06 25.9 0.6 15.1 16 0 0 16 16 16 13 Ankyrin repeat Jun PF03957.13 KFO96284.1 - 5.6e-94 314.4 9.6 7.7e-94 313.9 9.6 1.2 1 0 0 1 1 1 1 Jun-like transcription factor bZIP_1 PF00170.21 KFO96284.1 - 8.6e-18 64.2 17.8 1.8e-17 63.2 17.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFO96284.1 - 2.6e-09 37.0 14.4 6.3e-09 35.8 14.4 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFO96284.1 - 7.8e-09 35.9 9.3 1.5e-08 35.0 9.3 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor ZapB PF06005.12 KFO96284.1 - 0.00045 20.6 6.2 0.0018 18.6 3.6 2.4 2 0 0 2 2 2 1 Cell division protein ZapB PspA_IM30 PF04012.12 KFO96284.1 - 0.007 16.0 5.7 0.007 16.0 5.7 1.4 1 1 0 1 1 1 1 PspA/IM30 family Fib_alpha PF08702.10 KFO96284.1 - 0.011 15.9 1.0 0.018 15.3 1.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Jnk-SapK_ap_N PF09744.9 KFO96284.1 - 0.021 15.0 7.1 0.036 14.3 7.1 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FlaC_arch PF05377.11 KFO96284.1 - 0.023 15.1 1.6 0.054 13.9 1.6 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Spc29 PF17082.5 KFO96284.1 - 0.038 13.8 3.3 0.11 12.3 1.5 2.1 2 0 0 2 2 2 0 Spindle Pole Component 29 TSC22 PF01166.18 KFO96284.1 - 0.049 14.0 0.9 0.17 12.2 0.9 2.0 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF3450 PF11932.8 KFO96284.1 - 0.1 11.9 4.5 0.15 11.3 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Antimicrobial_7 PF08102.11 KFO96284.1 - 0.39 11.0 3.1 11 6.4 0.6 3.0 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Seryl_tRNA_N PF02403.22 KFO96284.1 - 0.88 9.8 7.9 1.7 8.9 7.9 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 KFO96284.1 - 1.1 9.3 4.8 2 8.5 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DivIC PF04977.15 KFO96284.1 - 3.4 7.5 8.3 2 8.3 4.9 2.1 1 1 1 2 2 2 0 Septum formation initiator DUF724 PF05266.14 KFO96284.1 - 3.9 7.3 8.8 7.2 6.4 8.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FGGY_C PF02782.16 KFO96285.1 - 1.3e-47 162.2 0.1 1.9e-47 161.6 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KFO96285.1 - 1.1e-27 97.2 0.0 1.6e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KFO96285.1 - 0.01 15.4 0.2 0.14 11.6 0.0 2.5 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family HSP70 PF00012.20 KFO96285.1 - 0.031 12.5 0.0 0.044 12.0 0.0 1.1 1 0 0 1 1 1 0 Hsp70 protein zf-C3HC4 PF00097.25 KFO96286.1 - 5.2e-10 39.0 7.0 8.9e-10 38.3 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFO96286.1 - 2.4e-09 36.9 3.7 3.9e-09 36.2 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFO96286.1 - 2.9e-09 36.9 6.8 2.9e-09 36.9 6.8 1.9 2 1 1 3 3 2 2 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KFO96286.1 - 5.8e-09 35.8 5.2 5.8e-09 35.8 5.2 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFO96286.1 - 6.8e-08 32.7 8.7 1.1e-07 32.0 8.7 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KFO96286.1 - 4.1e-07 29.8 10.7 1.8e-06 27.7 2.3 2.5 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KFO96286.1 - 7.1e-07 29.0 8.4 1.8e-06 27.7 8.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFO96286.1 - 3.1e-05 23.8 8.2 0.00039 20.3 8.8 2.3 1 1 1 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.8 KFO96286.1 - 0.0079 16.0 2.5 0.015 15.1 2.5 1.5 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 KFO96286.1 - 0.026 14.5 4.8 0.14 12.2 4.7 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KFO96286.1 - 0.033 14.0 3.6 0.37 10.6 2.1 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Cys_rich_CPXG PF14255.6 KFO96286.1 - 0.19 11.6 3.9 2.3 8.2 0.3 2.3 2 0 0 2 2 2 0 Cysteine-rich CPXCG Baculo_IE-1 PF05290.11 KFO96286.1 - 0.2 11.6 6.4 0.22 11.5 5.9 1.4 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-rbx1 PF12678.7 KFO96286.1 - 0.24 11.7 10.4 1.2 9.5 10.4 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain HypA PF01155.19 KFO96286.1 - 0.3 11.1 1.9 0.77 9.8 1.9 1.6 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Elf1 PF05129.13 KFO96286.1 - 0.34 11.0 7.0 1.4 9.0 3.8 2.6 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like DZR PF12773.7 KFO96286.1 - 0.47 10.5 6.3 4.8 7.3 5.7 2.5 1 1 1 2 2 2 0 Double zinc ribbon Lar_restr_allev PF14354.6 KFO96286.1 - 1.2 9.6 5.2 9.3 6.7 1.3 2.4 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf-Di19 PF05605.12 KFO96286.1 - 1.5 9.2 6.7 35 4.8 6.5 2.3 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_9 PF14369.6 KFO96286.1 - 1.9 8.8 7.6 3.3 8.1 0.1 2.7 2 1 0 2 2 2 0 zinc-ribbon TerY_C PF15616.6 KFO96286.1 - 2.5 8.2 6.5 10 6.3 6.5 1.8 1 1 0 1 1 1 0 TerY-C metal binding domain p450 PF00067.22 KFO96287.1 - 9.6e-131 436.7 0.2 1.1e-130 436.5 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFO96288.1 - 3.4e-41 141.5 0.1 3.7e-41 141.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFO96289.1 - 8.2e-10 38.0 0.5 8.4e-10 38.0 0.5 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cadherin_3 PF16184.5 KFO96290.1 - 1.8e-10 40.8 0.0 1.9e-10 40.7 0.0 1.0 1 0 0 1 1 1 1 Cadherin-like CTF_NFI PF00859.18 KFO96291.1 - 3.5e-104 348.8 21.1 2e-103 346.4 22.6 1.5 2 0 0 2 2 2 1 CTF/NF-I family transcription modulation region NfI_DNAbd_pre-N PF10524.9 KFO96291.1 - 2.5e-25 88.0 5.4 4.4e-25 87.3 5.4 1.4 1 0 0 1 1 1 1 Nuclear factor I protein pre-N-terminus MH1 PF03165.16 KFO96291.1 - 6.1e-12 45.7 0.1 1.1e-11 44.8 0.1 1.5 1 0 0 1 1 1 1 MH1 domain TM2 PF05154.16 KFO96292.1 - 4.4e-17 62.1 5.5 6.6e-17 61.6 5.5 1.3 1 0 0 1 1 1 1 TM2 domain Ank_2 PF12796.7 KFO96293.1 - 2e-34 118.0 5.9 1.6e-14 54.3 0.0 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFO96293.1 - 8e-25 86.6 4.0 1.6e-14 53.8 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFO96293.1 - 1.5e-17 63.2 3.3 5.8e-05 23.4 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KFO96293.1 - 3.3e-17 62.6 1.8 4.2e-08 33.6 0.0 3.7 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFO96293.1 - 4.4e-16 57.4 0.1 0.00092 19.5 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat CTU2 PF10288.9 KFO96293.1 - 1.8 8.8 6.1 5.6 7.2 6.1 1.9 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 UCH PF00443.29 KFO96295.1 - 1.3e-42 146.1 2.6 1.3e-37 129.7 1.4 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFO96295.1 - 1.8e-15 57.4 14.4 2.3e-13 50.5 14.7 3.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase CDC45 PF02724.14 KFO96295.1 - 1.8 6.8 9.5 2.8 6.1 9.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DHR-2 PF06920.13 KFO96296.1 - 2e-212 706.6 4.1 2e-212 706.6 4.1 1.6 2 0 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 KFO96296.1 - 4e-53 180.1 0.2 7.7e-53 179.2 0.2 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 KFO96296.1 - 3.8e-37 127.2 0.5 1.9e-35 121.7 0.2 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3398) DOCK_N PF16172.5 KFO96296.1 - 0.038 12.9 1.8 0.063 12.2 0.0 2.2 3 0 0 3 3 3 0 DOCK N-terminus Fibrinogen_C PF00147.18 KFO96297.1 - 6.5e-54 183.1 1.3 1e-53 182.4 1.3 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain UPF0242 PF06785.11 KFO96297.1 - 7.1e-05 23.0 18.5 0.00011 22.4 18.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Spc29 PF17082.5 KFO96297.1 - 0.008 16.1 12.9 0.029 14.2 2.2 2.3 1 1 1 2 2 2 2 Spindle Pole Component 29 DUF1664 PF07889.12 KFO96297.1 - 0.023 14.7 1.6 0.023 14.7 1.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-C4H2 PF10146.9 KFO96297.1 - 0.061 13.6 5.9 0.092 13.0 5.9 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein YscJ_FliF_C PF08345.11 KFO96297.1 - 0.078 13.3 0.4 0.18 12.1 0.4 1.6 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal Atg14 PF10186.9 KFO96297.1 - 0.33 10.0 10.5 0.48 9.5 10.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Med15_fungi PF05397.12 KFO96297.1 - 0.34 11.2 9.7 0.89 9.9 9.7 1.7 1 0 0 1 1 1 0 Mediator complex subunit 15 DUF1465 PF07323.12 KFO96297.1 - 0.41 10.5 3.7 0.57 10.0 3.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1465) Spc7 PF08317.11 KFO96297.1 - 0.44 9.4 18.8 0.9 8.4 18.8 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein USP8_interact PF08941.10 KFO96297.1 - 0.47 10.3 10.8 1.1 9.1 2.5 2.2 2 0 0 2 2 2 0 USP8 interacting DUF4407 PF14362.6 KFO96297.1 - 1.3 8.3 4.9 2 7.7 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) WXG100 PF06013.12 KFO96297.1 - 1.9 8.8 8.6 0.2 11.9 1.0 2.8 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Jnk-SapK_ap_N PF09744.9 KFO96297.1 - 5.8 7.1 21.0 7.8 6.7 3.4 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 CALCOCO1 PF07888.11 KFO96297.1 - 5.9 5.6 17.9 0.88 8.4 7.3 1.9 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like HrpB2 PF09487.10 KFO96297.1 - 6.2 7.3 8.1 3.9 7.9 0.9 2.5 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB2) Golgin_A5 PF09787.9 KFO96297.1 - 8.5 5.7 21.3 0.24 10.8 10.7 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 5 DivIC PF04977.15 KFO96297.1 - 9.7 6.0 21.5 1 9.2 4.1 4.0 3 1 1 4 4 4 0 Septum formation initiator Peptidase_C54 PF03416.19 KFO96298.1 - 1.3e-106 356.0 0.0 1.8e-106 355.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 CENP-R PF06729.12 KFO96299.1 - 3.1e-55 185.9 0.9 3.5e-55 185.7 0.9 1.0 1 0 0 1 1 1 1 Kinetochore component, CENP-R EF-hand_7 PF13499.6 KFO96300.1 - 2.1e-14 53.7 2.0 4.5e-09 36.6 0.7 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KFO96300.1 - 3.5e-12 44.9 3.8 0.0022 17.4 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KFO96300.1 - 7.3e-11 41.8 5.8 4.2e-06 26.5 0.1 3.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KFO96300.1 - 1.5e-08 33.9 3.6 0.00056 19.6 0.1 4.1 3 1 1 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 KFO96300.1 - 5.2e-05 22.6 0.7 0.032 13.7 0.3 2.6 2 0 0 2 2 2 2 EF hand UPF0154 PF03672.13 KFO96300.1 - 0.08 13.0 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) EF_assoc_2 PF08356.12 KFO96300.1 - 0.085 12.9 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 EF hand associated EF-hand_4 PF12763.7 KFO96300.1 - 0.087 12.8 1.3 3.6 7.6 0.0 3.2 2 1 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 KFO96300.1 - 0.1 13.5 0.3 0.39 11.6 0.1 2.2 2 1 0 2 2 2 0 EF-hand domain PGM_PMM_I PF02878.16 KFO96301.1 - 3.4e-38 130.5 0.2 5.7e-38 129.7 0.2 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KFO96301.1 - 1.8e-31 108.7 0.0 3.5e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KFO96301.1 - 5.3e-19 68.7 0.0 1.2e-18 67.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KFO96301.1 - 1.1e-05 25.5 0.0 2.8e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Pkinase_Tyr PF07714.17 KFO96302.1 - 1.8e-88 296.2 0.0 2.3e-88 295.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO96302.1 - 5.6e-40 137.4 0.0 8.4e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kringle PF00051.18 KFO96302.1 - 5.1e-23 81.2 4.9 1.3e-22 79.9 4.9 1.8 1 0 0 1 1 1 1 Kringle domain I-set PF07679.16 KFO96302.1 - 1.8e-17 63.2 0.0 3e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO96302.1 - 2.7e-16 59.9 0.1 6.7e-16 58.7 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin domain Fz PF01392.22 KFO96302.1 - 2.8e-11 44.0 3.7 2.8e-11 44.0 3.7 2.2 2 0 0 2 2 2 1 Fz domain Ig_2 PF13895.6 KFO96302.1 - 1.5e-08 34.8 1.3 2.3e-08 34.3 0.1 1.9 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 KFO96302.1 - 1.3e-07 31.6 0.1 3.2e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFO96302.1 - 1.2e-05 25.4 0.4 0.00043 20.4 0.4 2.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain Haspin_kinase PF12330.8 KFO96302.1 - 0.027 13.4 0.1 0.044 12.7 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain TMEM154 PF15102.6 KFO96302.1 - 0.11 12.4 1.3 0.11 12.3 0.0 1.6 2 0 0 2 2 1 0 TMEM154 protein family C2-set_2 PF08205.12 KFO96302.1 - 1 9.5 3.6 0.39 10.8 0.2 2.2 2 1 0 2 2 1 0 CD80-like C2-set immunoglobulin domain VWA_N PF08399.11 KFO96303.1 - 4.2e-21 75.7 0.1 3.5e-18 66.3 0.1 3.3 2 1 0 2 2 2 1 VWA N-terminal dCache_1 PF02743.18 KFO96303.1 - 4e-15 56.3 0.5 5.4e-09 36.2 0.0 2.6 2 0 0 2 2 2 2 Cache domain VWA PF00092.28 KFO96303.1 - 9.4e-07 29.2 1.5 1.6e-06 28.5 1.5 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFO96303.1 - 1.2e-05 25.9 0.4 3.1e-05 24.6 0.4 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFO96303.1 - 0.092 12.7 0.2 0.19 11.7 0.2 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain RRM_1 PF00076.22 KFO96304.1 - 5e-26 90.3 1.4 3.4e-13 49.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFO96304.1 - 0.041 13.5 0.6 13 5.4 0.0 3.7 3 1 1 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFO96304.1 - 0.054 13.4 0.0 1.8 8.5 0.0 3.0 3 0 0 3 3 3 0 Occluded RNA-recognition motif Pkinase_Tyr PF07714.17 KFO96305.1 - 2.7e-128 426.7 0.0 1.3e-83 280.2 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFO96305.1 - 1.8e-63 214.4 0.0 4.5e-46 157.4 0.0 3.1 3 0 0 3 3 3 2 Protein kinase domain FERM_F2 PF18377.1 KFO96305.1 - 1.8e-56 189.7 0.1 4.8e-56 188.3 0.1 1.8 1 0 0 1 1 1 1 FERM F2 acyl-CoA binding protein-like domain Jak1_Phl PF17887.1 KFO96305.1 - 6e-50 169.0 0.2 1.1e-49 168.1 0.2 1.5 1 0 0 1 1 1 1 Jak1 pleckstrin homology-like domain FERM_F1 PF18379.1 KFO96305.1 - 1.2e-36 124.6 2.7 2e-36 123.9 0.7 2.4 2 0 0 2 2 2 1 FERM F1 ubiquitin-like domain SH2 PF00017.24 KFO96305.1 - 0.0006 19.9 0.1 0.0022 18.1 0.0 2.1 2 0 0 2 2 2 1 SH2 domain Kinase-like PF14531.6 KFO96305.1 - 0.0029 16.9 0.0 0.16 11.2 0.0 2.8 2 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KFO96305.1 - 0.018 14.7 1.1 0.052 13.1 0.0 2.3 3 0 0 3 3 3 0 RIO1 family ADK PF00406.22 KFO96306.1 - 9.6e-27 93.9 0.1 2.5e-14 53.6 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 KFO96306.1 - 6.5e-14 51.6 0.0 1.5e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 KFO96306.1 - 1.1e-12 48.6 0.2 8.7e-12 45.6 0.1 2.2 2 1 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 KFO96306.1 - 1.9e-05 24.5 0.0 3.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase AAA_18 PF13238.6 KFO96306.1 - 2.9e-05 24.6 0.1 0.0051 17.4 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFO96306.1 - 0.0042 17.3 0.1 0.021 15.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KFO96306.1 - 0.055 13.9 0.1 0.088 13.2 0.1 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PTEN_C2 PF10409.9 KFO96307.1 - 3.6e-28 98.0 0.0 6.8e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DnaJ PF00226.31 KFO96307.1 - 1.9e-06 27.9 0.0 4.4e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Y_phosphatase PF00102.27 KFO96307.1 - 0.0036 16.9 0.1 0.0065 16.1 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Vps55 PF04133.14 KFO96308.1 - 3.9e-39 133.2 6.6 4.3e-39 133.1 6.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 ObR_Ig PF18589.1 KFO96309.1 - 1.7e-70 234.1 2.8 2.7e-34 117.7 0.1 2.7 2 0 0 2 2 2 2 Obesity receptor immunoglobulin like domain Lep_receptor_Ig PF06328.11 KFO96309.1 - 6e-24 83.8 0.2 1.9e-23 82.2 0.2 1.9 1 0 0 1 1 1 1 Ig-like C2-type domain fn3 PF00041.21 KFO96309.1 - 4.2e-06 27.0 4.8 0.0011 19.3 0.0 4.5 4 0 0 4 4 4 1 Fibronectin type III domain PDEase_I PF00233.19 KFO96311.1 - 1.8e-93 312.6 4.8 1.8e-93 312.6 4.8 2.0 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase PDE4_UCR PF18100.1 KFO96311.1 - 4.6e-56 188.6 1.4 4.6e-56 188.6 1.4 2.2 2 0 0 2 2 2 1 Phosphodiesterase 4 upstream conserved regions (UCR) DFP PF04127.15 KFO96311.1 - 0.47 10.2 2.2 0.4 10.5 0.2 1.8 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Tctex-1 PF03645.13 KFO96312.1 - 7.2e-26 90.4 0.0 8e-26 90.3 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family Leu_zip PF15294.6 KFO96312.1 - 0.008 15.7 0.0 0.0093 15.5 0.0 1.1 1 0 0 1 1 1 1 Leucine zipper Insulin PF00049.18 KFO96313.1 - 0.021 15.8 0.1 0.023 15.7 0.1 1.1 1 0 0 1 1 1 0 Insulin/IGF/Relaxin family Ins_beta PF03488.14 KFO96313.1 - 0.04 13.9 0.3 0.045 13.8 0.3 1.1 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type WD40 PF00400.32 KFO96314.1 - 4.4e-10 40.0 2.4 0.0046 17.8 0.1 5.8 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO96314.1 - 2.2e-05 24.7 0.0 1.5 9.1 0.0 4.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain ELM2 PF01448.24 KFO96315.1 - 3.9e-12 46.7 3.8 9.4e-11 42.3 0.0 3.0 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-binding PF00249.31 KFO96315.1 - 3.6e-07 30.3 0.1 9.4e-07 28.9 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFO96315.1 - 0.0051 16.7 1.0 0.02 14.8 0.0 2.5 2 0 0 2 2 2 1 Myb DNA-binding like TPT PF03151.16 KFO96316.1 - 2.9e-11 43.2 6.9 3.3e-11 43.1 6.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFO96316.1 - 3.1e-05 24.2 18.7 0.0022 18.2 8.4 2.1 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 KFO96316.1 - 0.0038 16.2 0.8 0.0038 16.2 0.8 2.1 1 1 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 KFO96316.1 - 0.055 12.7 14.9 0.078 12.2 14.9 1.2 1 0 0 1 1 1 0 UAA transporter family DUF2070 PF09843.9 KFO96316.1 - 0.064 11.5 8.2 0.081 11.2 8.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HABP4_PAI-RBP1 PF04774.15 KFO96319.1 - 7e-33 113.9 11.5 2.3e-32 112.2 11.5 1.9 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family IHABP4_N PF16174.5 KFO96319.1 - 2e-06 28.5 9.7 2e-06 28.5 9.7 2.5 2 1 0 2 2 2 1 Intracellular hyaluronan-binding protein 4 N-terminal G-gamma PF00631.22 KFO96320.1 - 5.5e-17 61.5 0.0 6.2e-17 61.4 0.0 1.0 1 0 0 1 1 1 1 GGL domain CP12 PF02672.15 KFO96320.1 - 0.034 14.9 0.0 0.046 14.5 0.0 1.1 1 0 0 1 1 1 0 CP12 domain Ras PF00071.22 KFO96321.1 - 9.8e-47 158.6 0.1 1.2e-46 158.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO96321.1 - 2.5e-17 63.2 0.1 5.5e-17 62.1 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO96321.1 - 3.6e-07 29.8 0.0 5.7e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFO96321.1 - 3.4e-05 23.8 0.5 0.23 11.3 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFO96321.1 - 0.00032 20.8 0.0 0.00056 20.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFO96321.1 - 0.00064 19.2 1.1 0.0034 16.9 1.1 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KFO96321.1 - 0.0049 16.4 0.1 0.018 14.6 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KFO96321.1 - 0.015 14.3 0.1 1.5 7.8 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KFO96321.1 - 0.018 15.4 0.1 0.024 15.0 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KFO96321.1 - 0.022 15.0 0.1 0.085 13.1 0.0 2.1 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.18 KFO96321.1 - 0.03 13.9 0.1 0.18 11.3 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 KFO96321.1 - 0.043 13.5 0.6 0.11 12.1 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KFO96321.1 - 0.061 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1_Xtn PF16897.5 KFO96321.1 - 0.088 12.8 0.0 0.18 11.8 0.0 1.6 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain MIG-14_Wnt-bd PF06664.12 KFO96322.1 - 3.1e-94 315.5 21.2 3.9e-94 315.1 21.2 1.1 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion DUF5345 PF17280.2 KFO96322.1 - 6.4 6.8 8.8 0.63 10.1 1.2 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Carboxyl_trans PF01039.22 KFO96323.1 - 1.7e-93 314.0 0.0 2.3e-93 313.5 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain RPE65 PF03055.15 KFO96324.1 - 4.3e-119 398.7 0.0 4.9e-119 398.6 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DEP PF00610.21 KFO96325.1 - 1.2e-17 63.7 0.0 5.6e-17 61.6 0.0 2.2 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.27 KFO96325.1 - 0.0014 18.5 4.8 0.26 11.1 0.0 3.3 3 0 0 3 3 3 2 RhoGAP domain Cnd3 PF12719.7 KFO96325.1 - 0.0082 15.4 1.9 0.0082 15.4 0.2 1.8 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain DUF148 PF02520.17 KFO96325.1 - 0.02 15.0 1.1 0.02 15.0 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF148 TPR_20 PF14561.6 KFO96325.1 - 0.49 10.8 1.9 31 5.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_8 PF13855.6 KFO96326.1 - 4.4e-52 173.7 63.4 7.7e-12 44.8 8.1 9.1 5 1 6 11 11 11 10 Leucine rich repeat LRR_4 PF12799.7 KFO96326.1 - 7e-45 150.3 80.3 1.7e-07 31.4 2.0 12.3 5 3 9 15 15 15 13 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFO96326.1 - 3.9e-10 38.8 60.0 0.86 10.4 0.0 16.7 17 1 1 18 18 18 5 Leucine Rich Repeat LRR_9 PF14580.6 KFO96326.1 - 3.3e-09 36.5 30.8 0.0057 16.2 0.8 6.1 2 2 5 7 7 7 6 Leucine-rich repeat LRR_6 PF13516.6 KFO96326.1 - 0.17 12.0 0.2 0.17 12.0 0.2 14.3 16 0 0 16 16 16 0 Leucine Rich repeat GPCR_chapero_1 PF11904.8 KFO96328.1 - 3.8e-69 233.5 0.6 1e-68 232.1 0.6 1.6 1 1 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.7 KFO96328.1 - 1.3e-08 35.3 0.1 2.8e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFO96328.1 - 1.7e-08 34.5 0.3 3.3e-06 27.3 0.8 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KFO96328.1 - 1.7e-08 34.8 0.1 3.2e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFO96328.1 - 6.1e-08 32.3 0.1 0.0013 19.1 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KFO96328.1 - 5.7e-05 23.3 0.1 0.00011 22.4 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) 7tm_1 PF00001.21 KFO96329.1 - 9.9e-24 84.1 11.9 1.3e-23 83.7 11.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFO96329.1 - 1.1e-07 31.8 6.5 1.9e-07 31.0 4.8 1.8 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srbc PF10316.9 KFO96329.1 - 0.00055 19.5 0.1 0.00055 19.5 0.1 2.2 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc DUF2207 PF09972.9 KFO96329.1 - 9.4 4.9 9.4 1.2 7.8 5.2 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) zf-RanBP PF00641.18 KFO96330.1 - 1.7e-09 36.8 19.6 1.5e-06 27.4 9.5 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DUF35_N PF12172.8 KFO96330.1 - 0.021 14.7 8.3 0.58 10.1 1.0 2.4 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) RecR PF02132.15 KFO96330.1 - 2.6 7.7 7.2 0.8 9.3 1.1 2.3 2 0 0 2 2 2 0 RecR protein DZR PF12773.7 KFO96330.1 - 3.4 7.8 8.9 8.5 6.5 2.0 2.1 1 1 1 2 2 2 0 Double zinc ribbon I-set PF07679.16 KFO96331.1 - 4.4e-35 119.6 0.1 3.9e-12 46.1 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO96331.1 - 1.4e-34 118.5 0.5 2e-13 50.8 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFO96331.1 - 5.2e-27 94.0 1.0 2.7e-10 40.4 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFO96331.1 - 2.5e-24 85.3 1.0 2.4e-10 40.5 0.0 4.1 4 0 0 4 4 4 4 Immunoglobulin domain V-set PF07686.17 KFO96331.1 - 5.1e-13 49.2 4.4 1.7e-05 25.0 0.0 4.9 3 2 1 4 4 4 4 Immunoglobulin V-set domain Izumo-Ig PF16706.5 KFO96331.1 - 2.3e-07 30.8 0.8 0.0013 18.8 0.1 3.5 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFO96331.1 - 1.2e-06 28.8 0.0 0.2 12.1 0.0 3.3 3 0 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFO96331.1 - 4e-05 23.8 0.1 0.78 10.0 0.0 3.3 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFO96331.1 - 0.00058 19.4 0.0 0.45 10.1 0.0 3.0 3 0 0 3 3 3 1 Immunoglobulin domain C2-set_2 PF08205.12 KFO96331.1 - 0.00091 19.3 0.0 0.78 9.8 0.0 2.7 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Adeno_E3_CR1 PF02440.15 KFO96331.1 - 0.0031 17.3 2.7 0.92 9.3 0.1 3.7 3 1 0 3 3 3 1 Adenovirus E3 region protein CR1 Ig_C17orf99 PF17736.1 KFO96331.1 - 0.0077 16.3 0.1 0.12 12.4 0.0 2.8 3 1 0 3 3 3 1 C17orf99 Ig domain V-set_CD47 PF08204.11 KFO96331.1 - 0.013 15.5 0.0 7.7 6.5 0.1 2.8 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain Ank_2 PF12796.7 KFO96332.1 - 2.8e-61 204.1 26.2 8.7e-17 61.5 0.4 6.2 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.17 KFO96332.1 - 4.6e-57 193.2 0.0 6.9e-57 192.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO96332.1 - 4.9e-46 157.2 0.0 1.2e-45 155.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.6 KFO96332.1 - 5.1e-46 154.5 26.3 3.2e-10 40.3 0.0 7.6 4 4 5 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 KFO96332.1 - 1.3e-44 148.7 29.1 3.1e-07 30.5 0.0 11.4 12 1 0 12 12 11 8 Ankyrin repeat Ank_3 PF13606.6 KFO96332.1 - 2.1e-40 132.1 17.2 0.00058 20.1 0.0 11.3 12 0 0 12 12 11 7 Ankyrin repeat Ank_5 PF13857.6 KFO96332.1 - 6.7e-32 109.1 12.6 2.7e-05 24.3 0.3 9.8 3 2 7 10 10 10 8 Ankyrin repeats (many copies) Kdo PF06293.14 KFO96332.1 - 0.032 13.6 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFO96332.1 - 0.036 13.7 1.0 0.12 12.0 0.1 2.0 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 KFO96332.1 - 0.043 13.7 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KFO96332.1 - 0.061 12.6 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF4590 PF15257.6 KFO96333.1 - 4.2e-58 194.2 0.4 6.6e-58 193.6 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4590) ADH_zinc_N PF00107.26 KFO96334.1 - 4.2e-22 78.5 1.2 6.3e-22 78.0 0.4 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFO96334.1 - 4.9e-18 66.5 0.0 7.9e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFO96334.1 - 5.6e-12 45.5 0.1 6.1e-11 42.2 0.1 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain TYW3 PF02676.14 KFO96335.1 - 2.2e-31 108.9 0.2 2.3e-31 108.8 0.2 1.0 1 0 0 1 1 1 1 Methyltransferase TYW3 Choline_transpo PF04515.12 KFO96336.1 - 3.4e-113 378.1 33.9 3.4e-113 378.1 33.9 2.6 3 0 0 3 3 3 2 Plasma-membrane choline transporter UPF0242 PF06785.11 KFO96336.1 - 9 6.3 6.5 31 4.6 3.9 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Prenyltrans PF00432.21 KFO96337.1 - 2e-73 241.8 9.8 4.6e-16 58.3 0.1 5.9 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KFO96337.1 - 0.00028 20.1 0.0 0.00075 18.7 0.0 1.7 2 1 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KFO96337.1 - 0.0073 15.4 0.0 1.1 8.3 0.0 3.3 2 2 2 4 4 4 1 Squalene-hopene cyclase N-terminal domain MutS_V PF00488.21 KFO96338.1 - 2.5e-73 246.1 0.3 5.3e-73 245.1 0.3 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFO96338.1 - 4.3e-33 115.2 5.4 1.2e-32 113.7 0.8 2.8 3 0 0 3 3 3 1 MutS domain III MutS_II PF05188.17 KFO96338.1 - 2.1e-19 70.2 0.2 4.9e-19 69.0 0.2 1.6 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KFO96338.1 - 5.1e-16 58.8 0.0 1.2e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_14 PF13173.6 KFO96338.1 - 1.1e-05 25.5 1.4 0.00027 21.0 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFO96338.1 - 0.0096 15.7 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KFO96338.1 - 0.016 15.7 0.1 0.092 13.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KFO96338.1 - 0.054 13.4 0.8 0.4 10.6 0.8 2.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 KFO96338.1 - 0.12 12.1 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 KFO96338.1 - 0.13 12.8 0.0 0.42 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain NYD-SP12_N PF15015.6 KFO96339.1 - 6.1e-193 642.2 0.8 6.8e-193 642.1 0.8 1.0 1 0 0 1 1 1 1 Spermatogenesis-associated, N-terminal TPR_1 PF00515.28 KFO96339.1 - 0.00037 20.2 1.9 0.39 10.6 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFO96339.1 - 0.0014 18.9 1.5 1.7 9.0 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFO96339.1 - 0.0092 16.0 5.3 3.9 7.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat Carbam_trans_C PF16861.5 KFO96339.1 - 0.025 14.2 0.0 0.94 9.0 0.0 2.4 2 1 0 2 2 2 0 Carbamoyltransferase C-terminus TPR_14 PF13428.6 KFO96339.1 - 0.03 15.1 1.4 2.6 9.1 0.2 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO96339.1 - 0.099 12.9 0.8 16 5.8 0.2 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KFO96339.1 - 0.21 12.3 2.6 14 6.4 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFO96339.1 - 3.6 7.8 5.8 19 5.5 0.3 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat RhoGEF PF00621.20 KFO96341.1 - 1.1e-43 149.6 0.8 2e-43 148.7 0.8 1.5 1 0 0 1 1 1 1 RhoGEF domain PTCB-BRCT PF12738.7 KFO96341.1 - 7e-26 90.0 4.5 3.1e-19 68.7 0.1 3.5 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.26 KFO96341.1 - 1.5e-16 60.5 1.1 2.2e-07 31.2 0.1 3.0 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KFO96341.1 - 0.00058 20.2 0.0 0.03 14.7 0.0 2.9 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KFO96341.1 - 0.00084 19.6 0.1 2.6 8.4 0.1 2.6 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain DUF3810 PF12725.7 KFO96341.1 - 0.16 11.3 0.1 0.37 10.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Abhydrolase_3 PF07859.13 KFO96342.1 - 9.9e-54 182.4 0.1 2.2e-39 135.5 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 KFO96342.1 - 9.9e-08 31.3 0.0 3.7e-05 22.8 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Say1_Mug180 PF10340.9 KFO96342.1 - 6.1e-07 28.6 0.0 9e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KFO96342.1 - 0.00033 20.2 0.0 0.0013 18.3 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family PuR_N PF09182.10 KFO96342.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal AXE1 PF05448.12 KFO96342.1 - 0.012 14.3 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.7 KFO96342.1 - 0.016 14.2 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme TNF PF00229.18 KFO96343.1 - 1.3e-31 109.2 0.8 2e-31 108.6 0.8 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family fn3 PF00041.21 KFO96344.1 - 6.3e-99 324.5 3.7 4.7e-11 42.9 0.0 9.9 9 1 0 9 9 9 9 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFO96344.1 - 8.7e-25 87.1 0.5 0.14 12.7 0.1 9.6 9 0 0 9 9 9 6 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 KFO96344.1 - 2.7e-12 46.9 0.0 0.049 14.0 0.0 7.1 7 0 0 7 7 7 3 Uncharacterised conserved protein (DUF2369) Interfer-bind PF09294.10 KFO96344.1 - 2.7e-10 40.5 4.0 6.3 7.2 0.0 7.8 8 0 0 8 8 8 3 Interferon-alpha/beta receptor, fibronectin type III fn3_4 PF16794.5 KFO96344.1 - 4e-05 23.5 0.4 8.2 6.4 0.1 6.5 6 2 0 6 6 6 2 Fibronectin-III type domain fn3_2 PF16893.5 KFO96344.1 - 9.5e-05 22.5 0.0 1.7 8.8 0.0 5.2 5 0 0 5 5 5 1 Fibronectin type III domain Y_Y_Y PF07495.13 KFO96344.1 - 0.071 13.1 0.5 6.9 6.7 0.0 4.5 7 0 0 7 7 7 0 Y_Y_Y domain PX PF00787.24 KFO96345.1 - 3.3e-20 72.2 3.6 1.1e-19 70.5 3.6 1.9 1 0 0 1 1 1 1 PX domain PLDc PF00614.22 KFO96345.1 - 4.7e-16 58.2 2.1 6.1e-08 32.5 0.1 3.5 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KFO96345.1 - 1.7e-14 53.9 0.4 7e-09 35.7 0.1 3.1 2 1 0 2 2 2 2 PLD-like domain PH PF00169.29 KFO96345.1 - 4.5e-08 33.6 0.1 1.4e-07 31.9 0.1 2.0 1 0 0 1 1 1 1 PH domain DUF3785 PF12653.7 KFO96345.1 - 0.052 13.7 0.2 0.12 12.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3785) Pkinase PF00069.25 KFO96346.1 - 1.2e-65 221.6 0.0 3.2e-65 220.1 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain CNH PF00780.22 KFO96346.1 - 1.9e-60 204.8 0.0 2.9e-60 204.2 0.0 1.3 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.17 KFO96346.1 - 1.4e-48 165.4 0.0 2.8e-48 164.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Sugar_tr PF00083.24 KFO96347.1 - 6.1e-152 506.6 22.6 6.9e-152 506.4 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFO96347.1 - 8.2e-22 77.6 35.4 1e-17 64.1 5.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3054 PF11255.8 KFO96347.1 - 8.9 6.9 18.9 0.36 11.4 7.8 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3054) eIF-5a PF01287.20 KFO96348.1 - 9.8e-28 96.1 0.1 1.3e-27 95.6 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KFO96348.1 - 0.0037 17.3 0.4 0.0059 16.6 0.0 1.6 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain Ribosomal_L22e PF01776.17 KFO96349.1 - 1.1e-44 151.2 5.9 3.4e-44 149.7 5.9 1.6 1 1 0 1 1 1 1 Ribosomal L22e protein family AA_permease_2 PF13520.6 KFO96350.1 - 9.3e-47 159.8 56.6 2e-45 155.4 38.3 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 KFO96350.1 - 2.7e-37 128.5 37.4 2.7e-37 128.5 37.4 2.4 2 1 0 2 2 2 2 Amino acid permease AA_permease_C PF13906.6 KFO96350.1 - 1.7e-20 72.8 9.9 1.7e-20 72.8 9.9 4.6 4 0 0 4 4 4 1 C-terminus of AA_permease PMP22_Claudin PF00822.20 KFO96351.1 - 1.3e-19 70.6 11.1 1.9e-19 70.2 11.1 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFO96351.1 - 5.9e-05 22.9 13.9 0.0064 16.3 13.9 2.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Ski_Sno PF02437.17 KFO96352.1 - 7.8e-44 147.8 1.6 2.2e-43 146.4 1.6 1.8 1 0 0 1 1 1 1 SKI/SNO/DAC family c-SKI_SMAD_bind PF08782.10 KFO96352.1 - 1e-36 125.0 4.1 2.8e-36 123.6 4.1 1.8 1 0 0 1 1 1 1 c-SKI Smad4 binding domain Octopine_DH PF02317.17 KFO96352.1 - 0.15 12.1 2.2 0.51 10.4 1.4 2.2 1 1 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain DUF489 PF04356.12 KFO96352.1 - 0.38 10.7 9.7 0.2 11.7 6.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF489) L1R_F9L PF02442.17 KFO96352.1 - 1.1 9.0 4.0 2.1 8.1 4.0 1.4 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses Pkinase PF00069.25 KFO96353.1 - 2.3e-67 227.2 0.0 3.5e-67 226.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO96353.1 - 2.5e-34 118.8 0.0 3.6e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KFO96353.1 - 3.1e-15 55.8 7.6 6.3e-15 54.8 7.6 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PB1 PF00564.24 KFO96353.1 - 6.2e-11 42.1 0.0 1.7e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 PB1 domain Pkinase_C PF00433.24 KFO96353.1 - 1.8e-05 25.4 2.3 5.3e-05 23.8 2.3 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFO96353.1 - 4.3e-05 23.0 0.0 6.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFO96353.1 - 0.0092 15.0 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain C1_2 PF03107.16 KFO96353.1 - 0.019 15.3 2.9 0.041 14.2 2.9 1.5 1 0 0 1 1 1 0 C1 domain APH PF01636.23 KFO96353.1 - 0.03 14.2 0.0 0.094 12.6 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 KFO96353.1 - 0.031 13.9 0.1 0.79 9.3 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KFO96353.1 - 0.033 13.6 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PHD PF00628.29 KFO96353.1 - 0.9 9.5 4.9 1.9 8.5 4.9 1.5 1 0 0 1 1 1 0 PHD-finger 7tm_1 PF00001.21 KFO96354.1 - 0.0011 18.3 23.2 0.0024 17.2 23.2 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Sec62 PF03839.16 KFO96355.1 - 2.6e-77 259.2 3.4 2.6e-77 259.2 3.4 2.3 1 1 1 2 2 2 1 Translocation protein Sec62 DEP PF00610.21 KFO96355.1 - 0.01 15.8 0.1 0.029 14.4 0.0 1.7 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Ctr PF04145.15 KFO96355.1 - 0.33 11.6 0.1 0.33 11.6 0.1 2.7 2 1 0 2 2 2 0 Ctr copper transporter family Dsh_C PF12316.8 KFO96355.1 - 2.9 8.2 17.6 8.3 6.8 1.2 2.2 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal SAM_1 PF00536.30 KFO96356.1 - 9.9e-14 51.5 0.0 1.8e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFO96356.1 - 1.6e-09 37.7 0.0 3.7e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 KFO96356.1 - 0.17 12.1 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif LRR_4 PF12799.7 KFO96357.1 - 2.4e-18 65.9 41.6 0.0031 17.9 2.5 9.3 2 1 11 13 13 13 13 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFO96357.1 - 7.4e-17 59.9 36.1 0.013 15.5 0.0 13.5 14 0 0 14 14 14 7 Leucine Rich repeat LRR_1 PF00560.33 KFO96357.1 - 9e-09 34.7 38.0 1.1 10.1 0.2 13.7 14 1 0 14 14 14 2 Leucine Rich Repeat LRR_8 PF13855.6 KFO96357.1 - 4.1e-06 26.5 43.4 0.71 9.7 2.5 10.2 5 4 4 9 9 9 7 Leucine rich repeat Suppressor_P21 PF11479.8 KFO96357.1 - 0.11 12.7 0.1 0.43 10.8 0.0 2.0 2 0 0 2 2 2 0 RNA silencing suppressor P21 C-terminal domain LRR_8 PF13855.6 KFO96358.1 - 3.1e-47 158.2 51.7 2.7e-08 33.4 0.1 9.2 1 1 10 11 11 11 11 Leucine rich repeat LRR_4 PF12799.7 KFO96358.1 - 1.3e-36 123.9 68.2 2.2e-05 24.7 7.1 10.5 5 2 5 12 12 12 12 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFO96358.1 - 6.7e-07 29.0 34.8 0.00026 20.6 2.8 5.2 1 1 4 6 6 6 5 Leucine-rich repeat LRR_1 PF00560.33 KFO96358.1 - 5.9e-06 26.1 63.8 12 6.9 0.2 15.5 14 2 1 15 15 15 3 Leucine Rich Repeat RsmF_methylt_CI PF17126.5 KFO96358.1 - 0.0006 19.8 6.1 4.4 7.4 0.0 6.2 6 0 0 6 6 6 2 RsmF rRNA methyltransferase first C-terminal domain LRR_6 PF13516.6 KFO96359.1 - 3.1e-34 114.1 17.0 7.4e-05 22.5 0.2 8.0 8 0 0 8 8 8 7 Leucine Rich repeat LRR_1 PF00560.33 KFO96359.1 - 0.00037 20.6 0.1 24 6.0 0.1 5.9 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_8 PF13855.6 KFO96359.1 - 0.0006 19.5 12.4 0.25 11.1 0.2 5.9 5 2 1 6 6 6 3 Leucine rich repeat LRR_4 PF12799.7 KFO96359.1 - 0.0042 17.5 10.8 1.2 9.6 0.1 5.5 3 2 4 7 7 7 3 Leucine Rich repeats (2 copies) zf-H2C2_2 PF13465.6 KFO96360.1 - 2.4e-53 176.3 46.7 2.3e-09 37.2 0.2 9.4 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFO96360.1 - 5.5e-37 124.2 53.2 5.1e-06 26.7 0.5 8.6 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO96360.1 - 2.1e-31 105.9 51.8 0.00075 20.1 2.1 8.8 8 0 0 8 8 8 8 C2H2-type zinc finger BTB PF00651.31 KFO96360.1 - 6.6e-24 84.3 0.2 1.5e-23 83.1 0.2 1.6 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_6 PF13912.6 KFO96360.1 - 2.2e-12 46.6 45.2 0.022 14.8 0.2 8.6 8 1 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO96360.1 - 4.4e-12 45.9 28.6 0.0031 17.8 0.2 8.1 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFO96360.1 - 4.1e-07 29.6 36.4 0.08 12.7 0.5 8.6 8 0 0 8 8 8 2 C2H2-type zinc-finger domain zf-met PF12874.7 KFO96360.1 - 9.8e-07 29.0 52.6 0.0026 18.1 0.5 8.9 9 0 0 9 9 9 4 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFO96360.1 - 3.7e-05 23.9 30.3 0.051 13.9 0.5 5.5 3 1 2 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf-MYST PF17772.1 KFO96360.1 - 0.0009 18.8 21.2 6.1 6.5 0.1 8.1 8 1 1 9 9 9 1 MYST family zinc finger domain zf-C2H2_11 PF16622.5 KFO96360.1 - 0.0015 18.2 36.8 0.0016 18.2 0.4 8.1 8 0 0 8 8 8 1 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 KFO96360.1 - 0.0064 16.8 21.6 0.074 13.4 6.4 4.7 1 1 4 5 5 5 1 C2H2-type zinc ribbon zf_UBZ PF18439.1 KFO96360.1 - 0.0073 15.9 26.3 0.38 10.4 0.1 7.8 8 0 0 8 8 8 2 Ubiquitin-Binding Zinc Finger DUF3268 PF11672.8 KFO96360.1 - 0.017 15.5 19.9 0.4 11.0 0.6 4.4 3 1 1 4 4 4 0 zinc-finger-containing domain Zn-ribbon_8 PF09723.10 KFO96360.1 - 0.018 15.1 30.9 0.79 9.9 2.3 6.8 2 1 5 7 7 7 0 Zinc ribbon domain zf_C2H2_13 PF18508.1 KFO96360.1 - 0.036 13.7 8.9 4.2 7.0 0.0 5.1 5 0 0 5 5 5 0 Zinc finger domain ADK_lid PF05191.14 KFO96360.1 - 0.046 13.7 29.7 2.2 8.3 0.8 6.5 4 2 3 7 7 6 0 Adenylate kinase, active site lid DUF3342 PF11822.8 KFO96360.1 - 0.07 13.3 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) zinc_ribbon_15 PF17032.5 KFO96360.1 - 0.072 13.9 29.4 0.62 10.8 2.0 5.3 1 1 5 6 6 6 0 zinc-ribbon family Zn_ribbon_SprT PF17283.2 KFO96360.1 - 0.1 12.5 22.5 0.22 11.5 0.3 5.1 4 1 1 5 5 5 0 SprT-like zinc ribbon domain zf-BED PF02892.15 KFO96360.1 - 0.11 12.6 0.3 0.11 12.6 0.3 7.1 3 2 4 7 7 7 0 BED zinc finger zf-C2H2_3rep PF18868.1 KFO96360.1 - 0.2 12.3 24.1 4.6 7.9 0.4 5.9 1 1 5 6 6 6 0 Zinc finger C2H2-type, 3 repeats zf_C2H2_ZHX PF18387.1 KFO96360.1 - 0.2 11.3 0.1 0.2 11.3 0.1 6.6 3 1 4 7 7 7 0 Zinc-fingers and homeoboxes C2H2 finger domain Vps36-NZF-N PF16988.5 KFO96360.1 - 0.6 9.5 15.1 6 6.3 0.3 4.9 3 1 2 5 5 5 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain GAGA PF09237.11 KFO96360.1 - 0.78 9.6 10.9 26 4.7 0.1 5.1 2 2 3 6 6 6 0 GAGA factor zf-C2H2_9 PF16293.5 KFO96360.1 - 1.6 8.7 9.2 25 4.8 0.0 5.6 6 0 0 6 6 6 0 C2H2 type zinc-finger (1 copy) FYVE PF01363.21 KFO96360.1 - 2.1 8.5 34.0 9.1 6.5 6.2 5.4 1 1 3 4 4 3 0 FYVE zinc finger XPA_N PF01286.18 KFO96360.1 - 5.3 7.2 26.6 6.6 6.9 0.0 7.2 8 0 0 8 8 7 0 XPA protein N-terminal C1_4 PF07975.12 KFO96360.1 - 7.3 6.9 29.3 2.3 8.5 6.5 5.5 1 1 3 6 6 6 0 TFIIH C1-like domain Sarcoglycan_1 PF04790.13 KFO96362.1 - 2.4e-81 272.9 0.0 2.7e-81 272.7 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2345 PF10106.9 KFO96362.1 - 0.00023 21.1 0.0 0.0021 17.9 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2345) DUF1523 PF07509.11 KFO96362.1 - 0.17 11.2 0.2 0.36 10.2 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1523) Ribosomal_L22 PF00237.19 KFO96363.1 - 2e-22 79.4 0.6 3.4e-22 78.6 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e ANAPC4_WD40 PF12894.7 KFO96364.1 - 3.5e-27 94.5 2.0 8.1e-07 29.3 0.0 7.0 5 2 2 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFO96364.1 - 3.9e-23 81.3 38.0 0.00023 21.9 0.6 12.8 13 1 0 13 13 13 6 WD domain, G-beta repeat Nup160 PF11715.8 KFO96364.1 - 0.0021 16.8 0.3 0.43 9.2 0.1 3.6 3 1 1 4 4 4 1 Nucleoporin Nup120/160 CAF1 PF04857.20 KFO96365.1 - 1.5e-23 83.5 1.6 1.1e-11 44.5 0.1 2.4 1 1 0 2 2 2 2 CAF1 family ribonuclease FA_hydroxylase PF04116.13 KFO96366.1 - 6.2e-21 75.1 15.2 6.2e-21 75.1 15.2 3.0 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily La PF05383.17 KFO96367.1 - 1.4e-21 76.3 0.8 3.5e-21 75.0 0.2 2.1 2 0 0 2 2 2 1 La domain HLH PF00010.26 KFO96368.1 - 8.3e-17 60.9 0.1 1.5e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_51 PF18558.1 KFO96368.1 - 0.028 14.3 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain SAP30_Sin3_bdg PF13867.6 KFO96369.1 - 3.5e-26 91.3 0.7 6.5e-26 90.4 0.7 1.5 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 zf-SAP30 PF13866.6 KFO96369.1 - 6.8e-13 48.5 2.0 6.8e-13 48.5 2.0 1.7 2 0 0 2 2 2 1 SAP30 zinc-finger Glycos_transf_2 PF00535.26 KFO96370.1 - 2.6e-33 115.3 0.0 4.2e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFO96370.1 - 1.9e-28 99.3 1.2 2.7e-28 98.7 1.2 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 KFO96370.1 - 3.7e-06 26.5 0.2 9.9e-06 25.1 0.2 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KFO96370.1 - 5.8e-05 22.7 0.0 0.00018 21.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.6 KFO96370.1 - 0.0092 16.7 0.0 2.5 8.9 0.0 2.7 2 1 1 3 3 3 1 Ricin-type beta-trefoil lectin domain-like ig PF00047.25 KFO96371.1 - 1.3e-08 34.9 0.0 2.2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFO96371.1 - 7.9e-08 32.3 0.0 1.6e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO96371.1 - 2.7e-07 31.1 0.0 6.6e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFO96371.1 - 6.4e-06 26.3 0.3 0.0014 18.7 0.3 2.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KFO96371.1 - 0.00058 20.1 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFO96371.1 - 0.039 14.0 0.1 0.081 13.0 0.1 1.6 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 KFO96371.1 - 0.088 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFO96371.1 - 0.097 13.1 0.1 0.24 11.8 0.1 1.6 1 1 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain DUF719 PF05334.13 KFO96372.1 - 6.2e-71 238.5 2.4 6.2e-71 238.5 2.4 3.0 3 1 0 3 3 3 1 Protein of unknown function (DUF719) RLL PF10036.9 KFO96372.1 - 1.9 8.3 7.1 0.11 12.3 1.3 2.0 2 1 0 2 2 2 0 RNA transcription, translation and transport factor protein LON_substr_bdg PF02190.16 KFO96373.1 - 9.9e-23 81.1 0.0 1.3e-22 80.7 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KFO96373.1 - 5.8e-10 38.9 14.2 5.8e-10 38.9 14.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFO96373.1 - 6.1e-09 35.6 9.9 1.5e-08 34.3 9.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFO96373.1 - 2.7e-07 30.8 14.4 2.7e-07 30.8 14.4 2.5 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 KFO96373.1 - 3.5e-07 30.2 11.0 8.3e-07 28.9 9.1 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFO96373.1 - 3.8e-07 29.9 13.2 3.8e-07 29.9 13.2 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFO96373.1 - 2.4e-06 27.3 11.0 6e-06 26.0 11.0 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFO96373.1 - 1.3e-05 25.1 14.9 4.3e-05 23.4 14.9 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFO96373.1 - 0.00011 22.3 13.1 0.00046 20.3 13.1 2.2 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KFO96373.1 - 0.00023 21.2 7.1 0.00057 20.0 7.1 1.7 1 0 0 1 1 1 1 zinc RING finger of MSL2 U-box PF04564.15 KFO96373.1 - 0.00094 19.3 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-rbx1 PF12678.7 KFO96373.1 - 0.0042 17.3 11.5 0.013 15.8 11.5 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KFO96373.1 - 0.034 14.0 8.6 0.076 12.9 8.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KFO96373.1 - 0.38 10.6 12.5 2.1 8.2 12.5 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KFO96373.1 - 1.6 8.5 7.2 4.6 7.1 5.5 2.8 2 0 0 2 2 2 0 RING-like zinc finger zf-P11 PF03854.14 KFO96373.1 - 2.2 8.0 16.5 2.5 7.8 6.6 2.5 1 1 1 2 2 2 0 P-11 zinc finger ANF_receptor PF01094.28 KFO96374.1 - 1.6e-69 234.7 0.1 2.4e-69 234.1 0.1 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 KFO96374.1 - 1.5e-59 200.1 0.0 2.5e-59 199.4 0.0 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFO96374.1 - 1.2e-44 151.2 0.0 3e-44 149.9 0.0 1.7 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFO96374.1 - 3.7e-24 85.4 0.0 7.6e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF659 PF04937.15 KFO96374.1 - 0.005 16.7 0.1 0.014 15.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF2061 PF09834.9 KFO96374.1 - 0.093 13.3 0.1 0.32 11.5 0.1 2.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2061) 7tm_1 PF00001.21 KFO96375.1 - 5.4e-50 170.2 19.7 8.2e-50 169.6 19.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFO96375.1 - 3.4e-10 39.7 19.5 6.6e-10 38.8 19.5 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFO96375.1 - 0.0002 21.1 21.2 0.0002 21.1 21.2 2.5 1 1 2 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 KFO96375.1 - 0.00024 20.5 18.4 0.0066 15.8 18.4 2.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 KFO96375.1 - 0.00048 20.0 17.1 0.0017 18.2 17.1 1.9 1 1 0 1 1 1 1 Olfactory receptor HRG PF16954.5 KFO96375.1 - 0.083 13.3 0.4 0.083 13.3 0.4 2.7 3 0 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene HTH_11 PF08279.12 KFO96375.1 - 0.16 11.9 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 HTH domain Neur_chan_LBD PF02931.23 KFO96376.1 - 1.1e-53 181.9 0.0 1.4e-53 181.6 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFO96376.1 - 1.9e-40 139.4 0.9 7.5e-34 117.8 0.1 2.1 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region HMA PF00403.26 KFO96377.1 - 1.7e-10 41.2 0.1 2.2e-10 40.8 0.1 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain RXLR_WY PF18634.1 KFO96377.1 - 0.082 12.9 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 RXLR phytopathogen effector protein WY-domain SPARC_Ca_bdg PF10591.9 KFO96378.1 - 3.6e-41 140.0 0.6 8.4e-41 138.8 0.6 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_1 PF00050.21 KFO96378.1 - 1.5e-15 56.9 7.3 1.3e-14 53.9 4.9 2.7 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KFO96378.1 - 3.8e-12 46.1 2.6 3.8e-12 46.1 2.6 3.0 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain FOLN PF09289.10 KFO96378.1 - 5.2e-09 36.1 9.5 5.2e-09 36.1 9.5 2.2 3 0 0 3 3 3 1 Follistatin/Osteonectin-like EGF domain EF-hand_1 PF00036.32 KFO96378.1 - 0.024 14.2 0.2 0.2 11.3 0.1 2.5 2 1 0 2 2 2 0 EF hand hEGF PF12661.7 KFO96378.1 - 0.035 14.7 3.2 0.12 13.0 3.2 2.0 1 1 0 1 1 1 0 Human growth factor-like EGF DUF4801 PF16059.5 KFO96378.1 - 0.049 13.6 8.0 0.13 12.2 8.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4801) Cadherin PF00028.17 KFO96379.1 - 0 1597.6 45.9 3e-22 78.9 0.0 33.7 34 0 0 34 34 34 33 Cadherin domain Cadherin_2 PF08266.12 KFO96379.1 - 1.3e-20 73.0 0.2 0.3 11.0 0.1 18.1 23 0 0 23 23 23 2 Cadherin-like RET_CLD1 PF17756.1 KFO96379.1 - 6.1e-19 68.5 0.0 0.24 11.7 0.0 15.0 18 1 0 18 18 17 2 RET Cadherin like domain 1 Cadherin_3 PF16184.5 KFO96379.1 - 1.6e-17 63.5 44.2 0.21 11.6 0.1 19.8 22 0 0 22 22 22 4 Cadherin-like Laminin_G_2 PF02210.24 KFO96379.1 - 2e-17 64.0 0.2 8.3e-17 61.9 0.2 2.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFO96379.1 - 1.7e-10 41.2 0.0 7.8e-10 39.1 0.0 2.3 2 0 0 2 2 1 1 Laminin G domain EGF PF00008.27 KFO96379.1 - 1.3e-09 38.1 51.4 3.5e-06 27.2 8.3 3.8 4 0 0 4 4 3 3 EGF-like domain Cadherin_4 PF17803.1 KFO96379.1 - 0.00026 21.5 93.2 0.054 14.1 0.5 19.4 19 0 0 19 19 19 2 Bacterial cadherin-like domain Laminin_G_3 PF13385.6 KFO96379.1 - 0.0021 18.2 0.1 0.036 14.2 0.0 3.0 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily EGF_2 PF07974.13 KFO96379.1 - 0.0027 18.0 11.2 0.0027 18.0 11.2 3.8 3 0 0 3 3 3 2 EGF-like domain hEGF PF12661.7 KFO96379.1 - 0.0048 17.5 34.5 0.095 13.4 3.5 4.0 3 0 0 3 3 3 3 Human growth factor-like EGF FlgD_ig PF13860.6 KFO96379.1 - 0.089 12.7 0.0 0.88 9.5 0.0 3.0 1 0 0 1 1 1 0 FlgD Ig-like domain DUF5077 PF16871.5 KFO96379.1 - 0.19 11.6 0.6 2.5 7.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5077) DUF4394 PF14339.6 KFO96379.1 - 2.3 7.5 7.8 1.5 8.1 0.1 4.8 6 0 0 6 6 6 0 Domain of unknown function (DUF4394) Big_9 PF17963.1 KFO96379.1 - 5 7.9 88.6 0.38 11.5 0.3 19.9 22 0 0 22 22 21 0 Bacterial Ig domain Aa_trans PF01490.18 KFO96380.1 - 1e-73 248.4 27.9 1.2e-73 248.2 27.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ACD PF16671.5 KFO96380.1 - 0.14 10.4 0.0 0.22 9.8 0.0 1.1 1 0 0 1 1 1 0 Actin cross-linking domain E1_DerP2_DerF2 PF02221.15 KFO96381.1 - 2.7e-27 95.8 0.0 3.2e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 ML domain DUF2443 PF10398.9 KFO96382.1 - 0.059 13.4 1.7 0.15 12.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) Sigma70_ner PF04546.13 KFO96382.1 - 0.16 11.8 12.1 0.19 11.6 12.1 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4140 PF13600.6 KFO96382.1 - 0.32 11.4 11.0 0.61 10.6 4.2 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF1664 PF07889.12 KFO96382.1 - 0.64 10.1 10.1 0.97 9.5 10.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF775 PF05603.12 KFO96382.1 - 0.9 9.0 4.9 1.1 8.7 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) FapA PF03961.13 KFO96382.1 - 1 7.9 12.1 1 7.9 12.1 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A NPV_P10 PF05531.12 KFO96382.1 - 1.3 9.6 6.2 1.5 9.3 0.8 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein LMBR1 PF04791.16 KFO96382.1 - 1.4 7.7 8.5 1.5 7.6 8.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein ALMT PF11744.8 KFO96382.1 - 3.9 6.2 9.7 4.4 6.0 9.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter XhlA PF10779.9 KFO96382.1 - 4.7 7.5 8.5 11 6.4 1.5 2.5 1 1 2 3 3 3 0 Haemolysin XhlA ZYG-11_interact PF05884.12 KFO96382.1 - 5.6 6.3 6.2 6.7 6.0 6.2 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ARD PF03079.14 KFO96382.1 - 6.8 6.9 9.5 1.6 8.9 2.5 1.8 1 1 0 1 1 1 0 ARD/ARD' family Annexin PF00191.20 KFO96383.1 - 3.4e-182 590.8 32.6 2.2e-25 88.5 0.6 8.1 8 0 0 8 8 8 8 Annexin Myb_DNA-bind_7 PF15963.5 KFO96383.1 - 0.00051 19.9 0.2 11 6.0 0.0 5.6 7 0 0 7 7 7 1 Myb DNA-binding like DUF5069 PF16798.5 KFO96383.1 - 0.002 18.4 0.1 0.65 10.2 0.0 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF5069) Sigma70_ner PF04546.13 KFO96383.1 - 0.0021 18.0 0.9 1.9 8.3 0.2 3.2 1 1 1 3 3 3 2 Sigma-70, non-essential region GGDEF_2 PF17853.1 KFO96383.1 - 0.015 15.5 0.1 0.33 11.2 0.0 3.0 2 1 1 3 3 3 0 GGDEF-like domain Acetyltransf_11 PF13720.6 KFO96383.1 - 0.11 13.0 3.5 49 4.5 0.0 4.8 5 0 0 5 5 5 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF5101 PF17031.5 KFO96383.1 - 0.13 12.3 1.0 9.7 6.4 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5101) DUF3574 PF12098.8 KFO96383.1 - 0.19 11.5 1.0 12 5.8 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3574) DUF2255 PF10012.9 KFO96383.1 - 0.5 10.5 1.9 1.2e+02 2.8 0.0 3.7 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2255) GSHPx PF00255.19 KFO96384.1 - 7.5e-24 83.4 0.1 9.8e-24 83.0 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Dynactin_p62 PF05502.13 KFO96385.1 - 7.3e-28 97.6 18.6 2.7e-15 56.1 3.8 2.5 1 1 1 2 2 2 2 Dynactin p62 family Elf1 PF05129.13 KFO96385.1 - 8.1 6.6 9.9 32 4.7 6.9 2.8 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like RRM_1 PF00076.22 KFO96386.1 - 2.9e-11 43.0 0.1 4.6e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KFO96386.1 - 2.8e-06 27.2 1.8 2.8e-06 27.2 1.8 2.1 2 0 0 2 2 2 1 Zinc finger domain Torus PF16131.5 KFO96386.1 - 4.3e-06 27.4 0.2 1.5e-05 25.7 0.0 1.9 2 0 0 2 2 2 1 Torus domain Nup35_RRM_2 PF14605.6 KFO96386.1 - 2.2e-05 24.4 0.0 4.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KFO96386.1 - 0.00018 21.3 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif zf-CCCH PF00642.24 KFO96386.1 - 0.0019 18.0 1.8 0.0019 18.0 1.8 2.6 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.11 KFO96386.1 - 0.0021 18.1 0.0 0.0049 16.9 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif zf-CCCH_4 PF18044.1 KFO96386.1 - 0.0056 16.4 1.8 0.013 15.3 1.8 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KFO96386.1 - 0.0093 16.2 0.6 0.02 15.1 0.2 1.7 2 0 0 2 2 2 1 Zinc-finger containing family FYVE PF01363.21 KFO96386.1 - 0.0098 16.0 0.6 0.0098 16.0 0.6 1.7 2 0 0 2 2 2 1 FYVE zinc finger zf-CCCH_2 PF14608.6 KFO96386.1 - 0.012 16.1 0.5 0.012 16.1 0.5 2.1 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zinc-ribbons_6 PF07191.12 KFO96386.1 - 1.9 8.5 9.2 4.5 7.3 9.2 1.6 1 0 0 1 1 1 0 zinc-ribbons Calsarcin PF05556.11 KFO96387.1 - 9.2e-32 110.6 0.0 5.1e-31 108.1 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) HSNSD PF12062.8 KFO96388.1 - 4.6e-257 853.5 0.0 6.1e-257 853.1 0.0 1.1 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.27 KFO96388.1 - 1e-46 159.6 0.0 1.6e-46 158.9 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFO96388.1 - 6.3e-06 26.7 0.2 0.0045 17.4 0.0 2.5 1 1 1 2 2 2 2 Sulfotransferase family Ribosomal_S11 PF00411.19 KFO96389.1 - 3.2e-47 159.5 0.4 4.1e-47 159.1 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 KFO96389.1 - 0.074 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) MHC2-interact PF09307.10 KFO96390.1 - 3e-33 114.0 3.5 4.8e-33 113.4 3.5 1.3 1 0 0 1 1 1 1 CLIP, MHC2 interacting MHCassoc_trimer PF08831.10 KFO96390.1 - 1.2e-31 108.6 5.8 2.1e-31 107.7 5.8 1.4 1 0 0 1 1 1 1 Class II MHC-associated invariant chain trimerisation domain Sema PF01403.19 KFO96390.1 - 0.14 11.0 0.2 0.17 10.6 0.2 1.1 1 0 0 1 1 1 0 Sema domain Treacle PF03546.14 KFO96391.1 - 8.5e-11 41.4 81.8 1.1e-09 37.7 31.6 6.6 1 1 5 6 6 6 4 Treacher Collins syndrome protein Treacle Sulfatase PF00884.23 KFO96392.1 - 4.1e-71 239.9 0.0 5.5e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KFO96392.1 - 0.0043 17.8 0.0 0.13 13.0 0.0 2.5 2 0 0 2 2 2 1 C-terminal region of aryl-sulfatase SNF PF00209.18 KFO96393.1 - 6.9e-227 754.3 38.5 7.9e-227 754.1 38.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Caveolin PF01146.17 KFO96393.1 - 2.4 8.1 8.6 0.75 9.8 2.4 2.8 3 0 0 3 3 3 0 Caveolin Phage_holin_2_3 PF16080.5 KFO96393.1 - 4.5 7.1 6.3 0.44 10.3 0.1 2.5 2 0 0 2 2 2 0 Bacteriophage holin family HP1 Caudal_act PF04731.12 KFO96394.1 - 3.4e-43 147.2 16.0 6.1e-43 146.4 16.0 1.4 1 0 0 1 1 1 1 Caudal like protein activation region Homeodomain PF00046.29 KFO96394.1 - 8.3e-21 73.6 1.5 1.4e-20 72.9 1.5 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO96394.1 - 0.0097 15.8 0.2 0.025 14.5 0.2 1.7 1 0 0 1 1 1 1 Homeobox KN domain Pkinase_Tyr PF07714.17 KFO96395.1 - 3e-108 361.0 0.0 4.6e-108 360.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO96395.1 - 3.5e-44 151.2 0.0 5.5e-27 94.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.6 KFO96395.1 - 5.5e-28 97.4 12.8 4.5e-10 40.0 0.2 5.5 5 1 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 KFO96395.1 - 5.9e-28 96.8 4.5 3.1e-10 40.0 0.1 4.7 4 1 0 4 4 4 4 Immunoglobulin I-set domain ig PF00047.25 KFO96395.1 - 4.6e-20 71.6 6.4 3.9e-07 30.1 0.1 5.7 5 1 0 5 5 5 3 Immunoglobulin domain Ig_2 PF13895.6 KFO96395.1 - 1.1e-19 70.5 10.4 7.2e-10 39.1 0.1 6.2 5 2 0 5 5 5 3 Immunoglobulin domain C2-set_2 PF08205.12 KFO96395.1 - 5.4e-06 26.4 10.1 0.21 11.7 0.1 4.9 4 1 0 4 4 4 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFO96395.1 - 9.6e-06 25.7 11.3 0.002 18.3 0.5 5.4 5 1 0 5 5 5 1 Immunoglobulin V-set domain Herpes_gE PF02480.16 KFO96395.1 - 5.3e-05 22.1 1.2 0.19 10.4 0.1 3.0 2 1 1 3 3 3 2 Alphaherpesvirus glycoprotein E Adeno_E3_CR1 PF02440.15 KFO96395.1 - 0.00071 19.3 0.6 3.3 7.6 0.0 3.8 3 0 0 3 3 3 1 Adenovirus E3 region protein CR1 Ig_5 PF16681.5 KFO96395.1 - 0.0011 19.3 4.5 0.34 11.3 0.1 4.8 4 2 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 KFO96395.1 - 0.0028 18.0 4.6 1.4 9.3 0.1 5.0 4 1 1 5 5 5 1 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFO96395.1 - 0.028 14.0 0.0 0.58 9.8 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain DUF4452 PF14618.6 KFO96395.1 - 0.058 13.3 0.1 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4452) Izumo-Ig PF16706.5 KFO96395.1 - 0.13 12.4 0.4 3.6 7.7 0.0 3.1 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain Pkinase_Tyr PF07714.17 KFO96396.1 - 1.1e-107 359.2 0.0 1.6e-107 358.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO96396.1 - 1.2e-43 149.4 0.0 1.7e-27 96.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain I-set PF07679.16 KFO96396.1 - 2.1e-32 111.0 0.0 1.1e-09 38.2 0.0 5.9 6 0 0 6 6 5 5 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO96396.1 - 1.6e-31 108.8 10.1 5e-09 36.6 0.1 5.7 5 1 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 KFO96396.1 - 8.1e-25 86.8 8.9 1.4e-11 44.4 0.0 5.3 5 1 0 5 5 5 3 Immunoglobulin domain Ig_2 PF13895.6 KFO96396.1 - 2e-21 76.1 8.4 6.1e-07 29.7 0.0 5.2 4 1 1 5 5 5 3 Immunoglobulin domain V-set PF07686.17 KFO96396.1 - 7.4e-10 39.0 9.4 0.0086 16.2 0.5 6.3 4 3 1 6 6 6 3 Immunoglobulin V-set domain Ig_4 PF16680.5 KFO96396.1 - 1.4e-08 34.9 2.9 0.00013 22.2 0.0 4.7 5 0 0 5 5 5 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFO96396.1 - 9.9e-07 29.1 5.5 0.0011 19.3 0.0 4.1 5 0 0 5 5 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFO96396.1 - 1.1e-06 28.6 0.1 0.57 10.3 0.0 4.0 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain C2-set PF05790.15 KFO96396.1 - 0.0017 18.5 1.3 2.7 8.2 0.1 3.6 4 0 0 4 4 3 1 Immunoglobulin C2-set domain C1-set PF07654.15 KFO96396.1 - 0.0036 17.6 2.6 0.14 12.6 0.1 3.5 3 0 0 3 3 3 1 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFO96396.1 - 0.0044 16.5 0.1 0.58 9.8 0.0 3.0 3 0 0 3 3 3 1 Immunoglobulin domain Lep_receptor_Ig PF06328.11 KFO96396.1 - 0.018 15.0 1.1 11 6.1 0.0 3.7 4 1 0 4 4 3 0 Ig-like C2-type domain APH PF01636.23 KFO96396.1 - 0.019 14.9 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family C2-set_2 PF08205.12 KFO96396.1 - 0.026 14.6 0.2 9 6.5 0.2 3.4 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain HMG_box_2 PF09011.10 KFO96397.1 - 1.2e-11 45.1 0.9 2.9e-11 43.8 0.9 1.7 1 0 0 1 1 1 1 HMG-box domain CxC4 PF18717.1 KFO96397.1 - 1.7e-10 40.8 0.1 5.3e-10 39.3 0.1 1.8 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases HMG_box PF00505.19 KFO96397.1 - 3.5e-10 40.1 0.8 8.7e-10 38.9 0.8 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box zf-IS66 PF13005.7 KFO96397.1 - 0.061 13.7 0.6 3.7 8.0 0.0 3.5 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 Zn_Tnp_IS91 PF14319.6 KFO96397.1 - 0.59 10.2 5.6 1.8 8.6 0.5 2.9 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-ribbon_3 PF13248.6 KFO96397.1 - 0.87 9.1 7.8 5.3 6.6 0.1 3.7 3 0 0 3 3 3 0 zinc-ribbon domain 7tm_1 PF00001.21 KFO96398.1 - 1.6e-53 181.8 22.3 1.9e-53 181.5 22.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFO96398.1 - 1.2e-11 44.5 20.1 1.7e-11 44.0 20.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFO96398.1 - 4.5e-07 29.9 16.5 7.3e-07 29.2 16.5 1.3 1 1 0 1 1 1 1 Olfactory receptor Cyclin_N PF00134.23 KFO96398.1 - 0.065 13.0 1.4 0.14 11.9 0.2 2.0 2 0 0 2 2 2 0 Cyclin, N-terminal domain Pkinase_Tyr PF07714.17 KFO96399.1 - 1.1e-109 365.7 0.0 1.6e-109 365.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ig_3 PF13927.6 KFO96399.1 - 2e-54 182.1 15.8 1.9e-11 44.4 0.0 7.1 6 1 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 KFO96399.1 - 1e-44 150.5 8.7 4.1e-14 52.4 0.1 7.5 7 0 0 7 7 7 4 Immunoglobulin I-set domain Pkinase PF00069.25 KFO96399.1 - 5.6e-43 147.2 0.0 5.1e-30 104.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Ig_2 PF13895.6 KFO96399.1 - 2e-37 127.4 16.3 1.1e-09 38.5 0.1 8.8 8 1 0 8 8 8 6 Immunoglobulin domain ig PF00047.25 KFO96399.1 - 7.3e-29 99.8 9.0 3.6e-07 30.3 0.1 6.7 6 0 0 6 6 6 4 Immunoglobulin domain V-set PF07686.17 KFO96399.1 - 7.1e-21 74.4 16.0 8.3e-06 25.9 0.2 7.8 6 3 0 6 6 6 4 Immunoglobulin V-set domain VEGFR-2_TMD PF17988.1 KFO96399.1 - 7.9e-20 70.0 3.7 1.5e-19 69.1 3.7 1.5 1 0 0 1 1 1 1 VEGFR-2 Transmembrane domain Izumo-Ig PF16706.5 KFO96399.1 - 1.7e-07 31.2 7.2 1.6 8.8 0.0 6.6 6 2 0 6 6 6 2 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFO96399.1 - 7.9e-07 29.4 7.6 0.64 10.5 0.0 6.7 6 1 1 7 7 7 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 KFO96399.1 - 1.7e-06 28.3 1.6 0.0026 18.1 0.1 4.7 4 0 0 4 4 4 1 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFO96399.1 - 1.3e-05 24.7 2.0 13 5.5 0.0 6.1 7 0 0 7 7 7 0 Immunoglobulin domain Ig_4 PF16680.5 KFO96399.1 - 1.6e-05 25.1 9.8 4.7 7.6 0.1 6.1 6 0 0 6 6 6 2 T-cell surface glycoprotein CD3 delta chain Receptor_2B4 PF11465.8 KFO96399.1 - 3e-05 24.2 0.7 0.024 14.8 0.1 3.7 3 0 0 3 3 3 1 Natural killer cell receptor 2B4 C2-set_2 PF08205.12 KFO96399.1 - 0.00056 19.9 4.4 1.3 9.2 0.0 4.7 5 0 0 5 5 4 1 CD80-like C2-set immunoglobulin domain Haspin_kinase PF12330.8 KFO96399.1 - 0.031 13.2 0.1 0.056 12.4 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Herpes_gE PF02480.16 KFO96399.1 - 0.034 12.9 0.0 2 7.1 0.0 2.9 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein E V-set_CD47 PF08204.11 KFO96399.1 - 0.34 10.9 4.0 2.8 7.9 0.0 3.7 4 0 0 4 4 4 0 CD47 immunoglobulin-like domain C2-set PF05790.15 KFO96399.1 - 0.48 10.6 1.9 2.7 8.2 0.0 3.3 4 0 0 4 4 3 0 Immunoglobulin C2-set domain Adeno_E3_CR1 PF02440.15 KFO96399.1 - 0.65 9.8 5.2 2.5 7.9 0.1 3.7 3 1 0 3 3 3 0 Adenovirus E3 region protein CR1 zf-RING_2 PF13639.6 KFO96400.1 - 8.6e-12 45.2 12.1 1.5e-11 44.4 12.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFO96400.1 - 1.8e-09 37.2 4.9 3.6e-09 36.2 4.9 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFO96400.1 - 2.4e-08 33.7 12.3 4.3e-08 32.9 12.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFO96400.1 - 2.1e-07 30.7 10.9 3.7e-07 29.9 10.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 KFO96400.1 - 2.8e-07 30.5 0.0 4.7e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.7 KFO96400.1 - 5.8e-07 29.7 10.0 1.2e-06 28.7 10.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFO96400.1 - 1.3e-06 28.3 9.9 2.1e-06 27.6 9.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFO96400.1 - 3.4e-05 23.6 9.1 6e-05 22.8 9.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFO96400.1 - 3.7e-05 23.6 7.4 6.7e-05 22.8 7.4 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFO96400.1 - 0.00014 21.7 8.3 0.00022 21.0 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFO96400.1 - 0.015 15.4 5.4 0.029 14.4 5.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PspB PF06667.12 KFO96400.1 - 0.054 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Phage shock protein B AbrB PF05145.12 KFO96400.1 - 0.065 12.2 0.2 0.097 11.6 0.2 1.2 1 0 0 1 1 1 0 Transition state regulatory protein AbrB Zn_ribbon_17 PF17120.5 KFO96400.1 - 0.076 12.6 9.9 0.23 11.1 10.0 1.7 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type Vps39_2 PF10367.9 KFO96400.1 - 0.21 12.1 0.1 0.21 12.1 0.1 2.6 3 1 1 4 4 4 0 Vacuolar sorting protein 39 domain 2 zinc_ribbon_16 PF17034.5 KFO96400.1 - 0.93 9.7 7.1 0.81 9.9 4.6 2.0 1 1 1 2 2 2 0 Zinc-ribbon like family zf-C3H2C3 PF17122.5 KFO96400.1 - 1.3 9.2 7.3 2.7 8.1 7.3 1.5 1 0 0 1 1 1 0 Zinc-finger PHD PF00628.29 KFO96400.1 - 1.9 8.5 10.6 3.1 7.7 10.6 1.4 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 KFO96400.1 - 2 8.6 5.7 5 7.3 5.7 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger UBA_5 PF16577.5 KFO96401.1 - 4.8e-41 138.7 0.1 8.3e-41 138.0 0.1 1.4 1 0 0 1 1 1 1 UBA domain ZZ PF00569.17 KFO96401.1 - 3.4e-13 49.2 2.8 6.3e-13 48.3 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type PB1 PF00564.24 KFO96401.1 - 0.0074 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 PB1 domain C1_2 PF03107.16 KFO96401.1 - 0.13 12.6 5.8 0.27 11.6 5.8 1.6 1 0 0 1 1 1 0 C1 domain Glyco_transf_54 PF04666.13 KFO96403.1 - 1.7e-136 453.8 0.5 2.3e-136 453.4 0.5 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region STAR_dimer PF16544.5 KFO96403.1 - 0.32 10.6 2.9 0.18 11.4 0.3 2.0 2 0 0 2 2 2 0 Homodimerisation region of STAR domain protein Calreticulin PF00262.18 KFO96405.1 - 2.4e-166 553.1 15.5 3.8e-166 552.5 15.5 1.3 1 0 0 1 1 1 1 Calreticulin family Connexin PF00029.19 KFO96405.1 - 0.0042 16.9 3.8 0.017 14.9 3.8 1.9 1 1 0 1 1 1 1 Connexin MAP17 PF15807.5 KFO96405.1 - 0.011 15.9 2.9 0.027 14.7 2.9 1.6 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Zip PF02535.22 KFO96405.1 - 0.13 11.4 0.7 0.22 10.7 0.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Astro_capsid_p PF12226.8 KFO96405.1 - 0.17 11.0 6.5 0.45 9.6 6.5 1.7 1 0 0 1 1 1 0 Turkey astrovirus capsid protein V_ATPase_I PF01496.19 KFO96405.1 - 0.21 9.4 1.5 0.29 9.0 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TRAP_alpha PF03896.16 KFO96405.1 - 2.8 7.1 16.6 1.5e+02 1.4 0.0 3.4 2 1 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit MAPEG PF01124.18 KFO96406.1 - 3.2e-15 56.2 2.0 4.1e-15 55.8 1.6 1.3 1 1 0 1 1 1 1 MAPEG family dNK PF01712.19 KFO96407.1 - 2.8e-70 236.4 1.0 3.1e-70 236.2 1.0 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 KFO96407.1 - 3e-06 27.8 0.1 3.6e-05 24.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFO96407.1 - 0.00029 21.0 0.0 0.0012 19.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KFO96407.1 - 0.0049 16.6 0.0 0.065 12.9 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.6 KFO96407.1 - 0.029 14.6 0.1 0.08 13.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFO96407.1 - 0.12 12.7 0.1 0.63 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain RRM_1 PF00076.22 KFO96408.1 - 4.1e-25 87.4 0.0 4.4e-13 48.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF PF08080.12 KFO96408.1 - 8.2e-14 51.3 14.6 4e-13 49.1 14.6 2.2 1 1 0 1 1 1 1 RNPHF zinc finger RRM_3 PF08777.11 KFO96408.1 - 0.00062 19.8 0.0 1 9.4 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif TNT PF14021.6 KFO96408.1 - 0.082 13.5 0.0 0.75 10.4 0.0 2.2 2 0 0 2 2 2 0 Tuberculosis necrotizing toxin Limkain-b1 PF11608.8 KFO96408.1 - 0.21 11.7 0.1 0.55 10.3 0.1 1.7 1 0 0 1 1 1 0 Limkain b1 RUN PF02759.19 KFO96409.1 - 1.5e-30 105.9 0.0 1.5e-30 105.9 0.0 1.8 2 1 0 2 2 2 1 RUN domain Macoilin PF09726.9 KFO96409.1 - 1.1e-05 24.3 15.0 1.1e-05 24.3 15.0 1.1 1 0 0 1 1 1 1 Macoilin family ADIP PF11559.8 KFO96409.1 - 0.012 15.8 6.3 0.012 15.8 6.3 2.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding GIT_CC PF16559.5 KFO96409.1 - 2.8 7.8 14.4 0.37 10.7 0.5 3.7 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.12 KFO96409.1 - 4.1 7.9 27.4 0.78 10.2 8.2 3.6 2 1 1 3 3 3 0 Cell division protein ZapB Pep_M12B_propep PF01562.19 KFO96410.1 - 6.1e-34 117.2 0.0 1.4e-33 116.1 0.0 1.7 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_spacer1 PF05986.14 KFO96410.1 - 3.1e-25 88.4 0.0 6.8e-25 87.3 0.0 1.6 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.19 KFO96410.1 - 3.6e-20 71.9 63.1 1.4e-10 41.2 7.7 6.0 7 0 0 7 7 7 4 Thrombospondin type 1 domain Reprolysin PF01421.19 KFO96410.1 - 2.9e-18 66.5 0.0 5.2e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 KFO96410.1 - 7.6e-18 64.8 16.6 2e-17 63.4 5.9 5.2 7 0 0 7 7 3 2 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 KFO96410.1 - 7.6e-14 52.3 0.1 7.6e-14 52.3 0.1 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFO96410.1 - 1.2e-10 42.0 0.1 2.6e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFO96410.1 - 1.9e-09 37.7 0.2 3.8e-09 36.7 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFO96410.1 - 2.9e-06 27.1 0.1 5.6e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFO96410.1 - 0.0013 18.6 0.1 0.003 17.4 0.1 1.6 1 0 0 1 1 1 1 Matrixin PLAC PF08686.11 KFO96410.1 - 0.013 16.2 7.8 0.013 16.2 7.8 3.4 3 0 0 3 3 3 0 PLAC (protease and lacunin) domain DUF4953 PF16313.5 KFO96410.1 - 0.099 11.8 0.3 0.17 11.1 0.3 1.2 1 0 0 1 1 1 0 Met-zincin DEPP PF15343.6 KFO96411.1 - 0.0051 16.9 0.0 0.0051 16.9 0.0 2.7 3 0 0 3 3 3 1 Decidual protein induced by progesterone family Exo_endo_phos PF03372.23 KFO96412.1 - 7.8e-21 74.7 0.0 3.3e-20 72.6 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 KFO96412.1 - 4.1e-11 42.5 12.2 9.2e-11 41.3 8.7 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFO96412.1 - 2.9e-10 40.2 17.5 2.5e-07 30.9 1.5 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFO96412.1 - 0.0058 17.0 16.1 12 6.9 0.1 5.7 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 KFO96412.1 - 0.21 11.8 17.4 1.2 9.4 0.2 4.6 4 0 0 4 4 4 0 Leucine Rich repeat Pkinase PF00069.25 KFO96413.1 - 4.5e-64 216.4 0.0 5.6e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO96413.1 - 1.2e-29 103.3 0.1 1.7e-29 102.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFO96413.1 - 1.8e-06 27.5 0.3 2.9e-06 26.8 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFO96413.1 - 4.6e-05 22.9 0.1 0.001 18.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFO96413.1 - 0.00043 20.3 0.2 0.00089 19.2 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFO96413.1 - 0.0005 19.7 0.2 0.00091 18.9 0.2 1.4 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 KFO96413.1 - 0.068 12.8 0.3 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RasGEF PF00617.19 KFO96414.1 - 1.9e-52 178.0 0.3 4e-52 177.0 0.3 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KFO96414.1 - 4e-13 49.5 0.0 1.1e-12 48.0 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif Pkinase PF00069.25 KFO96415.1 - 3.5e-53 180.6 0.5 4.9e-53 180.2 0.5 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO96415.1 - 1.6e-25 89.9 1.3 3.9e-25 88.6 0.1 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase HMG_box PF00505.19 KFO96416.1 - 1.2e-22 80.1 1.7 2.2e-22 79.2 1.7 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFO96416.1 - 4e-10 40.2 2.9 4.1e-10 40.1 0.8 1.9 2 0 0 2 2 2 1 HMG-box domain Thg1 PF04446.12 KFO96417.1 - 1.4e-51 173.7 0.6 2.1e-51 173.2 0.6 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KFO96417.1 - 1.9e-49 166.8 0.5 3.6e-49 166.0 0.5 1.4 1 0 0 1 1 1 1 Thg1 C terminal domain LSM PF01423.22 KFO96418.1 - 6.4e-10 38.6 0.1 5.6e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 LSM domain Vitellogenin_N PF01347.22 KFO96420.1 - 4.2e-64 217.0 8.6 5.3e-64 216.7 8.6 1.1 1 0 0 1 1 1 1 Lipoprotein amino terminal region HEAT_2 PF13646.6 KFO96420.1 - 0.0039 17.5 0.4 1.3 9.5 0.1 2.7 2 0 0 2 2 2 2 HEAT repeats Ribosomal_S5_C PF03719.15 KFO96420.1 - 0.12 11.9 0.0 14 5.3 0.1 2.7 2 0 0 2 2 2 0 Ribosomal protein S5, C-terminal domain SH2 PF00017.24 KFO96421.1 - 3.5e-20 71.9 0.2 6.1e-20 71.1 0.2 1.4 1 0 0 1 1 1 1 SH2 domain PH PF00169.29 KFO96421.1 - 4.6e-19 68.9 0.7 8.7e-19 68.0 0.7 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFO96421.1 - 0.00053 20.4 1.5 0.0017 18.8 1.5 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain MAPKK1_Int PF08923.10 KFO96422.1 - 5.9e-50 168.1 0.0 6.5e-50 167.9 0.0 1.0 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting DnaJ PF00226.31 KFO96423.1 - 6.5e-27 93.4 0.6 6.5e-27 93.4 0.6 1.8 2 0 0 2 2 2 1 DnaJ domain DUF1977 PF09320.11 KFO96423.1 - 1.5e-16 60.5 0.9 3.4e-16 59.4 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) Histone PF00125.24 KFO96424.1 - 1.7e-19 70.5 0.0 2.2e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KFO96424.1 - 2.5e-13 49.5 0.5 5.7e-13 48.4 0.5 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KFO96424.1 - 0.0046 17.2 0.0 0.0074 16.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Sel1 PF08238.12 KFO96425.1 - 2.8e-09 37.4 3.1 3.6e-09 37.0 0.7 2.5 2 1 1 3 3 3 1 Sel1 repeat Epiglycanin_C PF14654.6 KFO96425.1 - 0.11 12.5 0.2 0.16 12.0 0.2 1.3 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Endomucin PF07010.12 KFO96426.1 - 5.1e-26 92.2 0.8 6.1e-26 92.0 0.8 1.1 1 0 0 1 1 1 1 Endomucin Pilin_N PF07790.11 KFO96426.1 - 0.017 16.0 0.0 0.019 15.9 0.0 1.1 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal Metallophos PF00149.28 KFO96427.1 - 3.2e-38 132.3 0.0 5.1e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Zip PF02535.22 KFO96428.1 - 3.4e-69 233.6 4.4 3.9e-69 233.4 4.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4271 PF14093.6 KFO96428.1 - 0.0011 18.9 2.5 0.0011 18.9 2.5 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4271) DUF3480 PF11979.8 KFO96429.1 - 7.8e-35 120.5 0.1 8.4e-35 120.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3480) Cdc6_C PF09079.11 KFO96430.1 - 3.9e-17 62.0 0.3 3.9e-17 62.0 0.3 2.2 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain AAA PF00004.29 KFO96430.1 - 1.8e-16 60.8 0.0 4.5e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BAH PF01426.18 KFO96430.1 - 1.5e-11 44.2 0.1 4.2e-11 42.8 0.1 1.8 1 0 0 1 1 1 1 BAH domain AAA_16 PF13191.6 KFO96430.1 - 2.9e-11 44.0 0.1 4.2e-10 40.3 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFO96430.1 - 4.9e-11 43.1 0.0 1.5e-10 41.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_lid_10 PF17872.1 KFO96430.1 - 1.3e-09 38.1 0.1 3.8e-09 36.6 0.1 1.8 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 KFO96430.1 - 0.00011 22.5 0.0 0.00032 21.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFO96430.1 - 0.00051 19.8 0.0 0.00096 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KFO96430.1 - 0.0018 17.6 0.0 0.0037 16.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) TniB PF05621.11 KFO96430.1 - 0.025 14.0 0.0 0.21 11.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein NACHT PF05729.12 KFO96430.1 - 0.04 13.8 0.2 0.2 11.5 0.2 2.2 1 1 0 1 1 1 0 NACHT domain PIF1 PF05970.14 KFO96430.1 - 0.1 11.7 0.2 0.38 9.9 0.0 1.9 2 0 0 2 2 2 0 PIF1-like helicase PRP38 PF03371.15 KFO96431.1 - 1.1e-63 214.2 0.9 1.4e-63 213.9 0.9 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 KFO96431.1 - 6.9e-06 26.6 50.9 6.9e-06 26.6 50.9 2.2 1 1 1 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF2457 PF10446.9 KFO96431.1 - 6.6 5.8 40.2 13 4.7 40.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2457) PAP_assoc PF03828.19 KFO96432.1 - 1.8e-30 104.9 0.7 9.7e-16 57.7 0.2 3.0 2 0 0 2 2 2 2 Cid1 family poly A polymerase zf-CCHC PF00098.23 KFO96432.1 - 1.1e-11 44.2 21.7 4.6e-05 23.3 1.0 3.9 3 0 0 3 3 3 3 Zinc knuckle NTP_transf_2 PF01909.23 KFO96432.1 - 4.4e-10 39.7 0.0 1.1e-07 32.1 0.0 2.7 2 0 0 2 2 2 1 Nucleotidyltransferase domain zf-CCHC_4 PF14392.6 KFO96432.1 - 2.6e-05 23.8 14.9 0.25 11.1 0.6 3.7 3 0 0 3 3 3 3 Zinc knuckle Polbeta PF18765.1 KFO96432.1 - 4.8e-05 23.4 0.0 0.055 13.6 0.0 2.6 2 0 0 2 2 2 2 Polymerase beta, Nucleotidyltransferase zf-CCHC_2 PF13696.6 KFO96432.1 - 0.0031 17.3 38.8 0.055 13.3 6.7 5.4 5 0 0 5 5 5 3 Zinc knuckle Ubiq_cyt_C_chap PF03981.12 KFO96432.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone zf-CCHC_6 PF15288.6 KFO96432.1 - 9.1 6.2 10.9 34 4.4 0.2 3.1 2 0 0 2 2 2 0 Zinc knuckle GSHPx PF00255.19 KFO96433.1 - 2.1e-36 123.8 0.1 2.9e-36 123.3 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KFO96433.1 - 6.6e-06 26.0 0.0 4e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFO96433.1 - 0.1 12.3 0.0 0.95 9.2 0.0 2.0 2 0 0 2 2 2 0 Redoxin Shisa PF13908.6 KFO96434.1 - 0.00011 22.5 7.0 0.00011 22.5 7.0 2.0 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator PRIMA1 PF16101.5 KFO96434.1 - 0.016 15.2 0.1 0.019 15.0 0.1 1.1 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 PDR_assoc PF08370.11 KFO96434.1 - 0.05 13.3 5.5 0.09 12.5 5.5 1.4 1 1 0 1 1 1 0 Plant PDR ABC transporter associated Metallothio_Cad PF07846.11 KFO96434.1 - 5.4 7.2 9.7 0.92 9.7 5.7 1.8 2 1 0 2 2 2 0 Metallothionein family Sel1 PF08238.12 KFO96435.1 - 1.5e-17 63.6 0.5 1.6e-05 25.4 0.0 4.4 4 0 0 4 4 4 4 Sel1 repeat DUF4315 PF14193.6 KFO96435.1 - 0.17 11.9 3.1 0.34 11.0 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) LRR_4 PF12799.7 KFO96436.1 - 6.6e-05 23.2 9.5 0.015 15.7 0.3 4.0 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) BAF250_C PF12031.8 KFO96436.1 - 0.0028 17.0 2.3 0.0035 16.7 1.0 1.8 2 0 0 2 2 2 1 SWI/SNF-like complex subunit BAF250/Osa DNA_alkylation PF08713.11 KFO96436.1 - 0.016 14.9 1.7 4.6 6.9 0.1 2.7 3 0 0 3 3 3 0 DNA alkylation repair enzyme DUF3361 PF11841.8 KFO96436.1 - 0.063 13.2 11.9 0.1 12.5 0.7 4.4 3 1 2 5 5 5 0 Domain of unknown function (DUF3361) His_kinase PF06580.13 KFO96436.1 - 0.15 12.4 1.4 0.36 11.2 0.4 2.1 2 0 0 2 2 2 0 Histidine kinase LRR_8 PF13855.6 KFO96436.1 - 0.32 10.8 4.8 4.3 7.2 0.1 3.9 4 0 0 4 4 4 0 Leucine rich repeat Arm PF00514.23 KFO96436.1 - 1.5 9.0 7.9 97 3.2 0.1 5.5 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat ECH_1 PF00378.20 KFO96437.1 - 8.4e-52 176.0 0.1 9.3e-52 175.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFO96437.1 - 2.2e-27 96.4 0.3 1.5e-26 93.7 0.2 1.8 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase SCP2 PF02036.17 KFO96438.1 - 4.8e-30 104.0 0.9 1e-29 103.0 0.9 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family Thiolase_N PF00108.23 KFO96438.1 - 1.3e-20 73.8 0.0 1e-18 67.7 0.0 2.9 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFO96438.1 - 7.6e-11 41.7 1.5 1.1e-09 38.0 0.1 2.8 2 1 1 3 3 3 1 Thiolase, C-terminal domain Alkyl_sulf_C PF14864.6 KFO96438.1 - 2.8e-06 27.6 0.0 5.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 KFO96438.1 - 0.00016 22.0 0.0 0.0003 21.1 0.0 1.4 1 0 0 1 1 1 1 Sterol carrier protein domain ketoacyl-synt PF00109.26 KFO96438.1 - 0.00023 20.8 1.3 0.0027 17.3 0.9 2.7 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KFO96438.1 - 0.0013 18.5 1.0 0.016 15.1 0.1 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 KFO96438.1 - 0.0082 14.9 0.2 0.21 10.2 0.0 2.3 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.22 KFO96438.1 - 0.018 15.1 0.1 0.12 12.4 0.0 2.3 2 1 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain LRRNT PF01462.18 KFO96439.1 - 7.2e-06 25.5 1.8 1.3e-05 24.7 1.8 1.5 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain SDF PF00375.18 KFO96440.1 - 3.3e-125 418.1 28.2 3.8e-125 417.9 28.2 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF2417 PF10329.9 KFO96440.1 - 0.088 12.2 0.8 0.14 11.5 0.1 1.7 2 0 0 2 2 2 0 Region of unknown function (DUF2417) DUF866 PF05907.13 KFO96441.1 - 7.6e-48 162.3 0.0 9.3e-48 162.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Mago_nashi PF02792.14 KFO96442.1 - 2.1e-78 261.3 0.2 2.4e-78 261.1 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein Ldl_recept_a PF00057.18 KFO96443.1 - 3.4e-81 267.1 146.6 9.9e-14 51.3 16.7 8.3 8 0 0 8 8 8 7 Low-density lipoprotein receptor domain class A FXa_inhibition PF14670.6 KFO96443.1 - 4.8e-13 49.1 24.6 9.4e-11 41.8 7.7 6.3 7 1 0 7 7 7 2 Coagulation Factor Xa inhibitory site Ldl_recept_b PF00058.17 KFO96443.1 - 3.9e-11 43.2 0.0 7.6e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Low-density lipoprotein receptor repeat class B cEGF PF12662.7 KFO96443.1 - 3.6e-07 30.0 2.4 3.6e-07 30.0 2.4 5.3 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF_CA PF07645.15 KFO96443.1 - 3.4e-06 27.2 11.3 3.4e-06 27.2 11.3 10.1 5 2 3 8 8 8 2 Calcium-binding EGF domain EGF PF00008.27 KFO96443.1 - 4.8e-05 23.6 20.9 0.00014 22.1 6.0 9.1 9 0 0 9 9 9 2 EGF-like domain SKG6 PF08693.10 KFO96443.1 - 0.0007 19.0 1.8 0.0016 17.8 1.8 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 KFO96443.1 - 0.00088 19.2 0.9 0.0015 18.4 0.2 1.6 1 1 1 2 2 2 1 TMEM154 protein family EGF_3 PF12947.7 KFO96443.1 - 0.016 15.4 3.2 0.016 15.4 3.2 8.9 6 3 4 10 10 10 0 EGF domain PAP_PilO PF06864.12 KFO96443.1 - 0.18 10.6 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Pilin accessory protein (PilO) DM PF00751.18 KFO96444.1 - 1.2e-20 73.2 8.0 1.8e-20 72.6 8.0 1.3 1 0 0 1 1 1 1 DM DNA binding domain zf-C2H2 PF00096.26 KFO96445.1 - 4.1e-16 58.4 29.2 0.00097 19.5 0.6 6.8 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO96445.1 - 5.3e-11 42.4 20.2 4.8e-05 23.6 0.8 5.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFO96445.1 - 2e-07 31.2 25.9 0.005 17.6 0.2 6.6 6 0 0 6 6 6 4 C2H2-type zinc finger FOXP-CC PF16159.5 KFO96445.1 - 1.1e-06 29.2 18.0 0.0063 17.1 0.1 5.5 1 1 4 5 5 5 3 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KFO96445.1 - 0.0017 18.6 11.9 0.075 13.3 1.0 4.6 1 1 2 5 5 5 4 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KFO96445.1 - 0.058 13.5 9.9 14 5.8 0.1 4.6 1 1 3 4 4 4 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 KFO96445.1 - 0.1 12.9 6.6 14 6.1 0.2 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFO96445.1 - 0.1 12.6 3.0 1.6 8.8 0.1 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 KFO96445.1 - 0.5 10.8 7.0 3.2 8.3 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFO96445.1 - 2.1 8.2 11.3 28 4.6 0.1 5.0 4 0 0 4 4 4 0 C2H2-type zinc-finger domain Yip1 PF04893.17 KFO96446.1 - 1.3e-20 73.8 12.5 1.9e-20 73.3 12.5 1.3 1 0 0 1 1 1 1 Yip1 domain T4_deiodinase PF00837.17 KFO96447.1 - 1.8e-24 86.4 0.0 2e-24 86.2 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase F5_F8_type_C PF00754.25 KFO96448.1 - 0.0024 18.0 0.0 0.0031 17.6 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain ANAPC10 PF03256.16 KFO96448.1 - 0.17 11.5 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) LRR_6 PF13516.6 KFO96449.1 - 4.3e-06 26.3 9.8 0.053 13.6 0.2 4.3 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 KFO96449.1 - 0.00036 20.9 4.7 0.029 14.8 0.1 3.5 2 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFO96449.1 - 0.018 14.8 3.6 0.033 14.0 0.3 2.8 2 1 0 2 2 2 0 Leucine rich repeat Ldl_recept_a PF00057.18 KFO96450.1 - 3e-11 43.4 29.7 3.6e-05 23.9 6.4 3.4 3 1 0 3 3 3 3 Low-density lipoprotein receptor domain class A BSMAP PF12280.8 KFO96451.1 - 5.1e-71 238.8 0.4 6.7e-71 238.4 0.4 1.1 1 0 0 1 1 1 1 Brain specific membrane anchored protein Med26 PF08711.11 KFO96452.1 - 1.9e-10 40.6 0.1 1.9e-10 40.6 0.1 2.9 4 0 0 4 4 4 1 TFIIS helical bundle-like domain TFIIS_M PF07500.14 KFO96452.1 - 2.3e-08 34.5 0.1 8.9e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain CUB PF00431.20 KFO96453.1 - 2.7e-92 304.5 0.0 1e-31 109.5 0.0 3.0 3 0 0 3 3 3 3 CUB domain CUB_2 PF02408.20 KFO96453.1 - 0.0009 19.0 0.2 0.051 13.3 0.0 2.8 3 0 0 3 3 3 1 CUB-like domain FAD_binding_6 PF00970.24 KFO96454.1 - 5.6e-13 49.1 0.0 9.3e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KFO96454.1 - 1.4e-12 48.3 0.0 4.9e-12 46.5 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Oxidored-like PF09791.9 KFO96454.1 - 7.1e-12 44.8 1.3 1.1e-10 41.0 2.3 2.1 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal NAD_binding_6 PF08030.12 KFO96454.1 - 0.00045 20.4 0.1 0.073 13.2 0.0 2.7 2 1 0 3 3 3 1 Ferric reductase NAD binding domain TrbC_Ftype PF09673.10 KFO96454.1 - 0.00089 19.3 0.0 0.12 12.4 0.0 2.3 2 0 0 2 2 2 1 Type-F conjugative transfer system pilin assembly protein DUF5522 PF17653.1 KFO96454.1 - 0.11 12.4 5.5 0.074 13.0 3.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5522) PDCD9 PF07147.12 KFO96455.1 - 1.1e-13 51.3 0.2 2.5e-09 36.9 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial 28S ribosomal protein S30 (PDCD9) SSDP PF04503.13 KFO96456.1 - 4.8e-81 273.2 82.3 5.8e-56 190.9 57.8 2.0 1 1 1 2 2 2 2 Single-stranded DNA binding protein, SSDP 4HBT PF03061.22 KFO96457.1 - 2.9e-17 62.8 0.1 2.4e-10 40.6 0.0 2.5 3 0 0 3 3 3 2 Thioesterase superfamily DUF4149 PF13664.6 KFO96458.1 - 5.2e-23 81.3 9.1 1.9e-22 79.5 6.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Ost5 PF05251.12 KFO96458.1 - 0.094 13.0 1.4 0.35 11.1 1.4 2.0 1 1 0 1 1 1 0 Oligosaccharyltransferase subunit 5 TPR_1 PF00515.28 KFO96459.1 - 3.7e-15 55.0 5.2 0.00033 20.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFO96459.1 - 1.1e-11 43.9 4.9 0.011 15.8 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFO96459.1 - 8.5e-07 28.7 1.8 0.33 11.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFO96459.1 - 1.9e-05 25.2 0.0 0.017 15.8 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO96459.1 - 7.8e-05 22.8 0.8 0.00021 21.5 0.8 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KFO96459.1 - 0.00022 21.5 3.1 0.088 13.1 0.6 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFO96459.1 - 0.015 15.3 2.0 10 6.4 0.1 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFO96459.1 - 0.026 15.0 0.1 0.076 13.5 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFO96459.1 - 0.11 12.4 3.5 9.9 6.2 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat HHH_8 PF14716.6 KFO96459.1 - 0.17 12.3 1.7 0.33 11.4 0.6 2.1 1 1 1 2 2 2 0 Helix-hairpin-helix domain tRNA-synt_2b PF00587.25 KFO96460.1 - 3.5e-37 128.1 0.0 4.6e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KFO96460.1 - 7.7e-06 26.0 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain GAGA PF09237.11 KFO96460.1 - 0.15 11.9 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 GAGA factor Zn-ribbon_8 PF09723.10 KFO96460.1 - 1.3 9.2 3.3 11 6.2 2.5 2.7 2 1 1 3 3 3 0 Zinc ribbon domain SHIPPO-rpt PF07004.12 KFO96461.1 - 1.8e-06 28.6 18.0 0.013 16.4 0.1 5.7 6 0 0 6 6 6 3 Sperm-tail PG-rich repeat ECR1_N PF14382.6 KFO96461.1 - 0.091 12.6 1.0 35 4.3 0.1 3.4 4 0 0 4 4 4 0 Exosome complex exonuclease RRP4 N-terminal region FAD_binding_4 PF01565.23 KFO96462.1 - 5.4e-17 61.8 0.1 8.5e-17 61.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain TMEM61 PF15105.6 KFO96463.1 - 1.7e-47 161.7 1.0 1.8e-47 161.6 1.0 1.0 1 0 0 1 1 1 1 TMEM61 protein family TMEM51 PF15345.6 KFO96463.1 - 0.14 12.0 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Peptidase_S8 PF00082.22 KFO96464.1 - 1.8e-21 76.7 1.1 2.3e-21 76.4 1.1 1.1 1 0 0 1 1 1 1 Subtilase family NRIP1_repr_4 PF15690.5 KFO96466.1 - 1e-163 544.0 8.7 1e-163 544.0 8.7 2.5 3 0 0 3 3 3 1 Nuclear receptor-interacting protein 1 repression 4 NRIP1_repr_1 PF15687.5 KFO96466.1 - 7.4e-139 462.7 22.1 7.4e-139 462.7 22.1 2.5 2 0 0 2 2 2 1 Nuclear receptor-interacting protein 1 repression 1 NRIP1_repr_2 PF15688.5 KFO96466.1 - 6.1e-128 427.2 20.5 6.1e-128 427.2 20.5 3.2 3 2 0 3 3 3 1 Nuclear receptor-interacting protein 1 repression 2 NRIP1_repr_3 PF15689.5 KFO96466.1 - 1.8e-39 133.9 1.1 1.8e-39 133.9 1.1 3.6 3 0 0 3 3 3 1 Nuclear receptor-interacting protein 1 repression 3 SLY PF12485.8 KFO96467.1 - 7e-53 179.5 6.0 7e-53 179.5 6.0 2.2 2 0 0 2 2 2 1 Lymphocyte signaling adaptor protein SAM_2 PF07647.17 KFO96467.1 - 1.2e-08 34.9 0.2 2.9e-08 33.7 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFO96467.1 - 2.9e-08 34.0 0.1 7.4e-08 32.7 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 KFO96467.1 - 7.4e-05 22.4 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFO96467.1 - 0.024 14.2 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 SH3 domain SAM_KSR1 PF13543.6 KFO96467.1 - 0.34 11.1 2.4 0.49 10.5 0.1 2.1 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 HSP70 PF00012.20 KFO96468.1 - 5.2e-114 381.6 0.2 2.7e-81 273.6 0.0 2.0 1 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KFO96468.1 - 2.6e-15 56.1 0.2 5.9e-11 41.8 0.0 3.0 3 0 0 3 3 3 2 MreB/Mbl protein BcrAD_BadFG PF01869.20 KFO96468.1 - 0.021 14.3 0.2 8.3 5.8 0.0 3.0 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.11 KFO96468.1 - 0.028 13.6 0.0 0.059 12.6 0.0 1.6 1 0 0 1 1 1 0 StbA protein FtsA PF14450.6 KFO96468.1 - 0.03 14.7 0.3 2.9 8.4 0.0 3.4 2 2 0 2 2 2 0 Cell division protein FtsA DDR PF08841.10 KFO96468.1 - 0.033 13.2 0.3 0.39 9.7 0.1 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Raco_middle PF17651.1 KFO96468.1 - 0.1 12.3 1.2 11 5.7 0.0 3.1 3 1 0 3 3 3 0 RACo middle region Lipase PF00151.19 KFO96470.1 - 2.5e-81 273.6 0.0 3e-81 273.3 0.0 1.1 1 0 0 1 1 1 1 Lipase DUF2000 PF09391.10 KFO96470.1 - 0.088 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2000) Ig_3 PF13927.6 KFO96471.1 - 2.5e-18 66.4 0.0 3.5e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFO96471.1 - 3.9e-16 58.9 0.0 5.6e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFO96471.1 - 1.1e-12 48.1 0.0 1.5e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFO96471.1 - 2.4e-08 34.0 0.0 5.5e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFO96471.1 - 6.6e-05 23.0 0.0 0.0023 18.1 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFO96471.1 - 0.00024 21.1 0.0 0.00027 20.9 0.0 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.12 KFO96471.1 - 0.05 13.7 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family Ig_6 PF18452.1 KFO96471.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFO96472.1 - 2.9e-74 245.2 0.0 6e-23 80.7 0.0 5.1 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO96472.1 - 3.6e-64 213.3 0.6 6.6e-16 58.7 0.1 5.6 5 0 0 5 5 5 4 Immunoglobulin domain ig PF00047.25 KFO96472.1 - 4.5e-43 145.3 0.0 1.2e-09 38.2 0.0 4.8 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFO96472.1 - 2.7e-42 143.0 0.0 2.8e-11 43.6 0.0 4.6 4 0 0 4 4 4 4 Immunoglobulin domain fn3 PF00041.21 KFO96472.1 - 3.7e-37 126.5 11.5 7.9e-15 55.0 0.9 4.2 3 0 0 3 3 3 3 Fibronectin type III domain V-set PF07686.17 KFO96472.1 - 5.8e-29 100.5 8.7 2.1e-08 34.3 0.0 7.2 6 3 0 6 6 4 4 Immunoglobulin V-set domain Ig_6 PF18452.1 KFO96472.1 - 1.6e-13 50.0 0.0 0.00069 19.1 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin domain Ig_5 PF16681.5 KFO96472.1 - 9e-08 32.4 0.0 0.18 12.3 0.0 4.5 4 0 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFO96472.1 - 2.5e-07 30.8 0.0 1 9.6 0.0 4.6 4 1 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 KFO96472.1 - 1.8e-05 24.7 0.0 0.89 9.6 0.0 4.2 4 0 0 4 4 4 1 C17orf99 Ig domain Receptor_2B4 PF11465.8 KFO96472.1 - 0.0011 19.1 0.2 9.7 6.4 0.0 4.5 3 2 1 4 4 4 1 Natural killer cell receptor 2B4 Izumo-Ig PF16706.5 KFO96472.1 - 0.022 14.8 0.5 64 3.7 0.0 4.5 5 0 0 5 5 4 0 Izumo-like Immunoglobulin domain Adeno_E3_CR1 PF02440.15 KFO96472.1 - 0.041 13.7 0.1 0.48 10.2 0.0 2.8 4 0 0 4 4 3 0 Adenovirus E3 region protein CR1 fn3_4 PF16794.5 KFO96472.1 - 0.081 12.9 0.1 9.4 6.2 0.0 3.2 3 0 0 3 3 3 0 Fibronectin-III type domain Gpi16 PF04113.14 KFO96472.1 - 0.11 10.9 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component C2-set PF05790.15 KFO96472.1 - 0.14 12.3 0.0 29 4.9 0.0 3.7 3 0 0 3 3 3 0 Immunoglobulin C2-set domain I-set PF07679.16 KFO96473.1 - 1.5e-71 236.5 0.0 6.3e-23 80.7 0.0 4.7 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO96473.1 - 2.2e-62 207.6 3.4 5.8e-17 62.1 0.1 5.8 6 0 0 6 6 5 4 Immunoglobulin domain ig PF00047.25 KFO96473.1 - 1.5e-38 130.8 0.0 6.4e-09 35.9 0.0 4.7 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFO96473.1 - 9.7e-35 118.8 0.0 1.1e-08 35.3 0.0 5.1 5 0 0 5 5 5 4 Immunoglobulin domain fn3 PF00041.21 KFO96473.1 - 3e-33 114.0 9.6 2.3e-12 47.1 0.3 4.2 3 0 0 3 3 3 3 Fibronectin type III domain V-set PF07686.17 KFO96473.1 - 6.8e-22 77.7 8.3 3.4e-09 36.8 0.0 7.6 6 2 1 7 7 7 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFO96473.1 - 5.7e-10 39.1 3.7 0.15 12.2 0.0 5.9 6 0 0 6 6 6 3 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFO96473.1 - 3.2e-09 36.2 0.0 1 9.0 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin domain Ig_5 PF16681.5 KFO96473.1 - 4.7e-09 36.5 0.0 0.63 10.5 0.0 4.7 4 0 0 4 4 4 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 KFO96473.1 - 0.00019 21.4 0.0 4.2 7.5 0.0 4.7 4 1 1 5 5 5 1 C17orf99 Ig domain Pur_ac_phosph_N PF16656.5 KFO96473.1 - 0.0002 21.9 3.4 0.14 12.8 0.2 3.9 3 1 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Big_4 PF07532.11 KFO96473.1 - 0.036 13.8 2.3 0.24 11.1 0.5 2.9 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 4) Izumo-Ig PF16706.5 KFO96473.1 - 0.044 13.9 0.3 36 4.5 0.0 4.0 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain fn3_4 PF16794.5 KFO96473.1 - 0.061 13.2 0.0 8.7 6.3 0.0 2.8 2 0 0 2 2 2 0 Fibronectin-III type domain YfhE PF14152.6 KFO96473.1 - 0.23 11.5 0.3 0.46 10.6 0.3 1.5 1 0 0 1 1 1 0 YfhE-like protein Ig_3 PF13927.6 KFO96474.1 - 1.2e-17 64.3 0.0 1.6e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFO96474.1 - 3.1e-15 56.0 0.0 4.5e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFO96474.1 - 1.1e-11 44.9 0.0 1.4e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFO96474.1 - 6e-08 32.7 0.0 1.3e-07 31.6 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFO96474.1 - 1.2e-05 25.5 0.0 0.00061 19.9 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFO96474.1 - 0.00042 20.3 0.0 0.00048 20.1 0.0 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 KFO96474.1 - 0.0066 16.5 0.0 0.68 10.0 0.0 2.1 2 0 0 2 2 2 1 C17orf99 Ig domain Ig_6 PF18452.1 KFO96474.1 - 0.09 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.6 KFO96475.1 - 4.9e-29 100.7 0.3 3.7e-13 49.9 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFO96475.1 - 1.5e-23 82.7 0.0 1.2e-10 41.4 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KFO96475.1 - 1.7e-21 76.3 0.1 3.9e-09 36.7 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFO96475.1 - 4.4e-21 74.9 0.1 9.8e-08 32.1 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.12 KFO96475.1 - 1.8e-17 63.2 0.1 4.6e-15 55.4 0.0 2.5 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFO96475.1 - 9.1e-14 51.6 0.3 0.0034 17.5 0.0 4.2 3 1 1 4 4 4 3 Immunoglobulin V-set domain C1-set PF07654.15 KFO96475.1 - 4.2e-10 39.9 0.1 4.3e-09 36.6 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Ig_5 PF16681.5 KFO96475.1 - 6.1e-07 29.8 0.0 0.027 14.8 0.0 3.2 3 0 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFO96475.1 - 8.2e-06 26.0 0.0 0.051 13.8 0.0 3.5 3 1 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFO96475.1 - 0.00029 20.8 0.0 1.9 8.6 0.0 3.2 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain Vg_Tdu PF07545.14 KFO96476.1 - 3.5e-20 71.5 0.4 5.2e-20 70.9 0.4 1.3 1 0 0 1 1 1 1 Vestigial/Tondu family HNOB PF07700.15 KFO96476.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Haem-NO-binding Snf7 PF03357.21 KFO96477.1 - 2e-44 151.2 28.4 2e-44 151.2 28.4 1.4 2 0 0 2 2 2 1 Snf7 DnaJ-X PF14308.6 KFO96477.1 - 0.00027 20.4 13.2 0.00027 20.4 13.2 1.6 1 1 1 2 2 2 1 X-domain of DnaJ-containing UCH PF00443.29 KFO96477.1 - 0.061 12.8 3.9 0.075 12.5 3.9 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF4400 PF14348.6 KFO96477.1 - 1.2 8.6 4.7 1.9 8.0 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Imm42 PF15593.6 KFO96477.1 - 1.6 9.1 8.3 21 5.5 8.3 2.1 1 1 0 1 1 1 0 Immunity protein 42 SICA_beta PF12878.7 KFO96477.1 - 5.2 7.2 14.0 14 5.8 14.0 1.8 1 1 0 1 1 1 0 SICA extracellular beta domain 7tm_1 PF00001.21 KFO96478.1 - 7.1e-76 255.0 10.7 9.9e-76 254.5 10.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFO96478.1 - 4.1e-08 32.9 11.4 2.4e-07 30.4 10.2 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.9 KFO96478.1 - 4.3e-07 29.6 17.1 2.3e-06 27.2 17.1 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFO96478.1 - 9.2e-05 22.2 14.6 9.2e-05 22.2 14.6 2.3 2 2 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2207 PF09972.9 KFO96478.1 - 0.65 8.7 0.0 0.65 8.7 0.0 2.7 2 1 0 3 3 3 0 Predicted membrane protein (DUF2207) PDZ PF00595.24 KFO96479.1 - 3.8e-56 187.4 11.7 1.6e-13 50.8 0.5 4.6 5 0 0 5 5 5 4 PDZ domain PDZ_6 PF17820.1 KFO96479.1 - 1.5e-50 168.9 10.4 2.1e-12 46.7 0.3 4.2 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 KFO96479.1 - 7.2e-33 112.8 5.4 1.6e-07 31.5 0.1 4.2 4 0 0 4 4 4 4 PDZ domain GRASP55_65 PF04495.14 KFO96479.1 - 5.4e-09 36.5 1.7 0.055 13.8 0.0 4.0 3 1 1 4 4 4 3 GRASP55/65 PDZ-like domain Tricorn_PDZ PF14685.6 KFO96479.1 - 3.7e-07 30.0 3.9 0.014 15.3 0.1 4.3 4 0 0 4 4 4 2 Tricorn protease PDZ domain DUF4265 PF14085.6 KFO96479.1 - 0.0069 16.4 0.5 0.026 14.5 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4265) DUF5354 PF17305.2 KFO96479.1 - 0.033 14.4 0.1 0.033 14.4 0.1 3.1 4 0 0 4 4 4 0 Family of unknown function (DUF5354) DUF3394 PF11874.8 KFO96479.1 - 0.05 13.3 0.3 5.8 6.5 0.0 3.3 3 1 0 4 4 4 0 Domain of unknown function (DUF3394) DUF1450 PF07293.11 KFO96479.1 - 1.3 8.8 6.8 12 5.7 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1450) ABA_GPCR PF12430.8 KFO96480.1 - 5.3e-43 146.9 11.0 5.3e-43 146.9 11.0 2.2 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KFO96480.1 - 7.9e-29 99.5 0.4 2.1e-28 98.2 0.1 1.9 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal DUF1772 PF08592.11 KFO96480.1 - 2 8.8 5.3 5.9 7.2 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) Connexin PF00029.19 KFO96481.1 - 9.3e-102 339.7 0.2 9.3e-102 339.7 0.2 1.9 2 0 0 2 2 2 1 Connexin Connexin50 PF03509.14 KFO96481.1 - 6.8e-32 110.1 2.6 1e-31 109.5 0.3 2.4 2 0 0 2 2 2 1 Gap junction alpha-8 protein (Cx50) Connexin40_C PF16791.5 KFO96481.1 - 1.7e-06 29.3 0.0 3.3e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Connexin 40 C-terminal domain Connexin PF00029.19 KFO96482.1 - 5.4e-100 334.0 2.7 7e-100 333.6 2.7 1.1 1 0 0 1 1 1 1 Connexin Connexin40_C PF16791.5 KFO96482.1 - 7.6e-38 130.0 3.5 7.6e-38 130.0 3.5 1.9 3 0 0 3 3 3 1 Connexin 40 C-terminal domain His_Phos_2 PF00328.22 KFO96483.1 - 2.4e-18 66.7 0.0 9.7e-17 61.4 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.22 KFO96483.1 - 0.15 11.8 0.0 2.7 7.7 0.0 2.5 3 0 0 3 3 3 0 Histidine phosphatase superfamily (branch 1) BCL9 PF11502.8 KFO96485.1 - 1.6e-20 72.6 2.0 6.2e-20 70.7 2.0 2.1 1 0 0 1 1 1 1 B-cell lymphoma 9 protein Glyco_transf_90 PF05686.12 KFO96486.1 - 7.1e-114 380.8 1.9 8.8e-114 380.5 1.9 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KFO96486.1 - 0.012 15.9 0.0 0.022 15.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Potyvirid-P3 PF13608.6 KFO96486.1 - 0.036 13.1 0.0 0.061 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein Tim17 PF02466.19 KFO96487.1 - 2.4e-20 72.9 5.6 3.5e-20 72.5 5.6 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family COX14 PF14880.6 KFO96487.1 - 0.22 11.4 2.7 6.5 6.7 0.3 2.7 2 1 0 2 2 2 0 Cytochrome oxidase c assembly V-set PF07686.17 KFO96488.1 - 4.6e-12 46.1 0.5 1e-11 45.0 0.5 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFO96488.1 - 1.8e-09 37.6 0.5 4.2e-09 36.3 0.1 1.8 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 KFO96488.1 - 3.6e-06 27.5 3.0 0.00011 22.8 0.2 2.6 2 1 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 KFO96488.1 - 7.1e-06 26.1 3.4 7.2e-05 22.9 0.9 2.8 2 1 0 2 2 2 1 Immunoglobulin domain Ig_6 PF18452.1 KFO96488.1 - 8.2e-05 22.1 0.0 0.00019 20.9 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFO96488.1 - 0.0011 19.0 3.3 0.0013 18.8 0.2 2.5 2 2 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFO96488.1 - 0.038 14.3 6.3 0.63 10.4 0.6 2.9 2 2 0 2 2 2 0 Immunoglobulin domain ADP_ribosyl_GH PF03747.14 KFO96489.1 - 5.3e-55 187.2 2.8 6.1e-55 187.0 2.8 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase V-set PF07686.17 KFO96490.1 - 3.8e-64 213.7 4.2 6.3e-13 48.8 0.0 7.2 7 0 0 7 7 7 7 Immunoglobulin V-set domain Ig_3 PF13927.6 KFO96490.1 - 1.6e-51 172.8 1.7 7e-07 29.8 0.0 8.2 7 0 0 7 7 7 7 Immunoglobulin domain I-set PF07679.16 KFO96490.1 - 4.6e-38 129.2 0.0 0.00037 20.5 0.0 9.7 7 4 0 7 7 7 7 Immunoglobulin I-set domain ig PF00047.25 KFO96490.1 - 3.3e-27 94.5 8.9 0.0004 20.5 0.1 8.9 7 4 0 7 7 7 6 Immunoglobulin domain Ig_2 PF13895.6 KFO96490.1 - 3e-25 88.3 7.9 0.0017 18.6 0.0 11.5 7 7 0 7 7 7 5 Immunoglobulin domain Izumo-Ig PF16706.5 KFO96490.1 - 2e-07 31.0 0.9 2.3 8.4 0.0 6.9 8 0 0 8 8 8 2 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFO96490.1 - 6.9e-07 28.7 0.0 1.4 8.6 0.0 5.3 5 0 0 5 5 5 2 Immunoglobulin domain Big_2 PF02368.18 KFO96490.1 - 0.0023 17.8 0.4 0.084 12.8 0.0 3.2 3 0 0 3 3 3 1 Bacterial Ig-like domain (group 2) C2-set PF05790.15 KFO96490.1 - 0.01 16.0 1.0 1.1 9.5 0.0 4.1 4 0 0 4 4 4 0 Immunoglobulin C2-set domain V-set PF07686.17 KFO96491.1 - 3.2e-33 114.2 11.3 1.8e-08 34.5 0.1 6.2 6 0 0 6 6 6 5 Immunoglobulin V-set domain Ig_3 PF13927.6 KFO96491.1 - 5.7e-30 103.8 11.2 7.9e-07 29.6 0.1 6.9 6 3 0 6 6 6 5 Immunoglobulin domain I-set PF07679.16 KFO96491.1 - 1.2e-21 76.5 7.0 5.4e-05 23.2 0.0 8.0 7 1 1 8 8 8 5 Immunoglobulin I-set domain ig PF00047.25 KFO96491.1 - 3.7e-18 65.5 13.7 3.5e-05 23.9 0.1 7.4 6 4 0 6 6 6 4 Immunoglobulin domain Ig_2 PF13895.6 KFO96491.1 - 1.9e-14 53.7 15.8 0.0043 17.3 0.1 8.7 5 5 0 5 5 5 4 Immunoglobulin domain Izumo-Ig PF16706.5 KFO96491.1 - 2.3e-05 24.4 0.4 1.1 9.3 0.0 5.1 6 0 0 6 6 6 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFO96491.1 - 0.0004 19.9 0.6 5.5 6.6 0.0 4.8 5 0 0 5 5 5 1 Immunoglobulin domain Ig_5 PF16681.5 KFO96491.1 - 0.016 15.6 0.4 11 6.6 0.0 4.8 5 1 0 5 5 5 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set PF07686.17 KFO96492.1 - 0.0012 19.0 0.1 0.0021 18.2 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFO96492.1 - 0.0081 16.2 0.2 0.015 15.4 0.2 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFO96492.1 - 0.032 14.4 0.0 0.063 13.5 0.0 1.5 1 1 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.6 KFO96492.1 - 0.05 14.2 0.8 0.084 13.5 0.1 1.9 2 0 0 2 2 2 0 Immunoglobulin domain Ig_3 PF13927.6 KFO96493.1 - 2.1e-05 25.1 0.3 0.13 12.9 0.1 2.7 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFO96493.1 - 0.00042 20.4 0.2 0.026 14.7 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.16 KFO96493.1 - 0.0007 19.6 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFO96493.1 - 0.0014 18.9 0.3 0.0061 16.9 0.1 2.0 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 KFO96493.1 - 0.016 15.4 1.7 2.3 8.5 0.5 2.9 2 1 0 2 2 2 0 Immunoglobulin domain Orthoreo_P10 PF07204.11 KFO96493.1 - 0.12 12.4 1.2 0.22 11.5 1.2 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 HAMP PF00672.25 KFO96494.1 - 0.77 10.2 2.5 81 3.7 0.0 3.4 4 0 0 4 4 4 0 HAMP domain zf-H2C2_2 PF13465.6 KFO96495.1 - 3.4e-53 175.8 47.3 1.6e-08 34.6 0.5 9.0 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFO96495.1 - 1.2e-46 154.6 62.4 9.9e-08 32.0 0.6 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO96495.1 - 2.2e-29 99.6 58.4 0.0018 18.9 0.3 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO96495.1 - 1.6e-12 47.4 19.4 0.18 12.1 0.5 7.4 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFO96495.1 - 4.2e-11 42.2 32.5 0.041 13.5 0.1 8.1 8 0 0 8 8 8 4 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFO96495.1 - 4.5e-10 39.5 30.8 0.027 14.6 3.1 6.6 2 2 6 8 8 8 7 Zinc ribbon domain XPA_N PF01286.18 KFO96495.1 - 1.4e-08 34.7 29.8 0.23 11.5 0.3 8.1 8 0 0 8 8 8 2 XPA protein N-terminal zf-C2H2_6 PF13912.6 KFO96495.1 - 3.5e-07 30.1 54.1 0.13 12.3 0.4 9.2 8 2 0 8 8 8 4 C2H2-type zinc finger zinc_ribbon_15 PF17032.5 KFO96495.1 - 6e-07 30.1 20.3 0.092 13.5 1.1 4.4 1 1 4 6 6 6 4 zinc-ribbon family DZR PF12773.7 KFO96495.1 - 1.1e-06 28.5 28.7 0.063 13.3 6.9 4.9 1 1 2 3 3 3 2 Double zinc ribbon C1_1 PF00130.22 KFO96495.1 - 1.5e-05 24.8 28.5 0.11 12.4 1.2 6.4 1 1 7 8 8 8 4 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-LYAR PF08790.11 KFO96495.1 - 5e-05 23.1 34.4 0.85 9.6 0.1 8.1 8 0 0 8 8 8 3 LYAR-type C2HC zinc finger DNA_RNApol_7kD PF03604.13 KFO96495.1 - 8e-05 22.2 30.4 1.1 9.0 0.2 8.0 8 0 0 8 8 8 2 DNA directed RNA polymerase, 7 kDa subunit FYDLN_acid PF09538.10 KFO96495.1 - 0.00026 21.6 11.7 21 5.9 0.0 6.5 1 1 5 6 6 6 0 Protein of unknown function (FYDLN_acid) ADK_lid PF05191.14 KFO96495.1 - 0.0016 18.4 20.7 0.8 9.7 1.2 6.3 1 1 5 6 6 6 2 Adenylate kinase, active site lid YhfH PF14149.6 KFO96495.1 - 0.004 17.1 29.8 3.8 7.6 0.1 7.9 8 0 0 8 8 8 1 YhfH-like protein CpXC PF14353.6 KFO96495.1 - 0.0053 16.8 23.9 2 8.5 0.2 7.3 2 2 5 7 7 7 1 CpXC protein Zn_ribbon_SprT PF17283.2 KFO96495.1 - 0.0053 16.6 31.3 0.054 13.4 2.6 6.5 5 3 1 6 6 6 3 SprT-like zinc ribbon domain TFIIS_C PF01096.18 KFO96495.1 - 0.0072 16.2 27.8 8.2 6.4 0.2 7.8 8 0 0 8 8 8 0 Transcription factor S-II (TFIIS) zf-trcl PF13451.6 KFO96495.1 - 0.014 15.3 26.6 5.3 7.0 0.1 7.6 8 0 0 8 8 8 0 Probable zinc-ribbon domain C1_4 PF07975.12 KFO96495.1 - 0.026 14.7 26.4 0.19 12.0 0.9 5.1 2 2 4 6 6 6 0 TFIIH C1-like domain OSTMP1 PF09777.9 KFO96495.1 - 0.034 13.5 6.8 0.024 14.0 4.5 1.8 1 1 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor zf-C2H2_11 PF16622.5 KFO96495.1 - 0.041 13.6 0.2 0.041 13.6 0.2 8.1 8 0 0 8 8 8 0 zinc-finger C2H2-type zf-C2HE PF16278.5 KFO96495.1 - 0.17 12.3 38.4 0.6 10.6 1.0 7.7 1 1 7 8 8 8 0 C2HE / C2H2 / C2HC zinc-binding finger LIM PF00412.22 KFO96495.1 - 0.17 12.1 31.0 2.2 8.5 0.4 6.0 1 1 4 6 6 6 0 LIM domain HTH_18 PF12833.7 KFO96495.1 - 0.19 12.0 2.1 90 3.4 0.0 4.6 4 1 1 5 5 5 0 Helix-turn-helix domain DUF3268 PF11672.8 KFO96495.1 - 0.39 11.1 20.3 1.9 8.8 1.0 4.5 1 1 6 7 7 7 0 zinc-finger-containing domain zf-AN1 PF01428.16 KFO96495.1 - 0.78 10.0 46.2 11 6.3 0.2 8.0 5 2 3 8 8 8 0 AN1-like Zinc finger Zn_ribbon_recom PF13408.6 KFO96495.1 - 0.79 10.3 35.9 12 6.6 0.3 6.4 2 2 3 5 5 5 0 Recombinase zinc beta ribbon domain Rpr2 PF04032.16 KFO96495.1 - 0.85 9.9 23.4 0.13 12.5 6.9 4.0 2 2 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zinc-ribbons_6 PF07191.12 KFO96495.1 - 1.3 9.1 29.0 4.1e+02 1.0 9.7 6.0 1 1 1 2 2 1 0 zinc-ribbons Yippee-Mis18 PF03226.14 KFO96495.1 - 2.3 8.5 26.1 1.9 8.7 1.5 5.8 3 2 2 5 5 5 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PknG_rubred PF16919.5 KFO96495.1 - 2.8 8.1 29.9 0.16 12.2 3.7 4.9 1 1 4 6 6 6 0 Protein kinase G rubredoxin domain BolA PF01722.18 KFO96495.1 - 3.1 8.1 9.4 17 5.8 0.5 3.6 2 2 1 3 3 3 0 BolA-like protein Chordopox_RPO7 PF05864.12 KFO96495.1 - 4 7.8 16.2 53 4.2 0.1 6.5 7 1 1 8 8 7 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) DUF2256 PF10013.9 KFO96495.1 - 6.2 7.0 22.3 44 4.3 0.0 7.1 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_9 PF14369.6 KFO96495.1 - 9.9 6.5 28.6 32 4.9 0.1 7.6 7 1 1 8 8 8 0 zinc-ribbon LSR PF05624.14 KFO96496.1 - 1.5e-24 85.7 33.5 2.3e-24 85.1 33.5 1.3 1 0 0 1 1 1 1 Lipolysis stimulated receptor (LSR) V-set PF07686.17 KFO96496.1 - 7.5e-06 26.1 0.4 0.0048 17.1 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin V-set domain ig PF00047.25 KFO96497.1 - 1.2e-14 54.2 1.5 7.2e-07 29.3 0.6 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 KFO96497.1 - 4.1e-14 52.9 3.2 1.8e-09 38.1 1.3 2.2 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFO96497.1 - 7.5e-13 48.6 2.1 4.8e-08 33.1 0.0 3.1 2 1 1 3 3 3 3 Immunoglobulin V-set domain Ig_2 PF13895.6 KFO96497.1 - 2.4e-12 47.0 1.6 3.4e-07 30.5 0.6 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFO96497.1 - 2.4e-12 46.7 0.2 1e-06 28.7 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_5 PF16681.5 KFO96497.1 - 8.7e-05 22.9 0.0 0.044 14.2 0.0 2.3 2 0 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFO96497.1 - 0.0003 20.8 0.0 0.1 12.7 0.0 2.2 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 KFO96497.1 - 0.00044 20.5 0.1 0.13 12.5 0.1 2.3 2 0 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFO96497.1 - 0.00086 18.8 5.4 0.24 11.0 0.0 2.8 3 0 0 3 3 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFO96497.1 - 0.0083 16.2 0.1 0.015 15.3 0.1 1.5 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Adeno_E3_CR1 PF02440.15 KFO96497.1 - 0.026 14.3 0.8 0.34 10.7 0.2 2.3 2 1 0 2 2 2 0 Adenovirus E3 region protein CR1 Herpes_gE PF02480.16 KFO96497.1 - 0.026 13.3 3.0 1.7 7.3 0.0 2.5 1 1 2 3 3 3 0 Alphaherpesvirus glycoprotein E BppU_N PF10651.9 KFO96497.1 - 0.043 13.5 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 BppU N-terminal domain stn_TNFRSF12A PF12191.8 KFO96497.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DSPc PF00782.20 KFO96498.1 - 2.1e-26 92.3 0.0 5.9e-26 90.8 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Pou PF00157.17 KFO96499.1 - 2.9e-38 129.7 0.2 7e-38 128.5 0.2 1.7 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KFO96499.1 - 1.4e-17 63.2 2.7 3.7e-17 61.9 2.7 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO96499.1 - 0.064 13.2 0.1 0.18 11.8 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain HTH_31 PF13560.6 KFO96499.1 - 0.089 13.1 1.2 1.4 9.3 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain TCR_zetazeta PF11628.8 KFO96500.1 - 6.9e-18 64.0 0.7 1e-17 63.5 0.7 1.3 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 zeta chain ITAM PF02189.15 KFO96500.1 - 3.7e-06 27.1 3.6 0.019 15.4 0.2 3.0 3 0 0 3 3 3 2 Immunoreceptor tyrosine-based activation motif Pyrid_oxidase_2 PF13883.6 KFO96501.1 - 5.7e-41 140.3 0.0 6.3e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CAP-ZIP_m PF15255.6 KFO96502.1 - 1.5e-20 73.9 1.6 1.5e-20 73.9 1.6 2.4 3 0 0 3 3 3 1 WASH complex subunit CAP-Z interacting, central region DUF5565 PF17720.1 KFO96503.1 - 3.6e-160 532.1 0.2 4.1e-160 532.0 0.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5565) TPR_2 PF07719.17 KFO96504.1 - 7.2e-41 135.0 15.9 9.3e-09 34.7 0.1 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_1 PF00515.28 KFO96504.1 - 4.4e-39 130.7 19.6 4.9e-10 38.8 0.1 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.6 KFO96504.1 - 1.4e-38 127.9 14.9 4.1e-06 26.6 0.0 9.2 9 0 0 9 9 9 8 Tetratricopeptide repeat DUF1736 PF08409.11 KFO96504.1 - 7.4e-32 109.2 1.2 1.7e-31 108.0 1.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_17 PF13431.6 KFO96504.1 - 2.4e-28 96.4 24.7 3.3e-06 27.1 0.3 10.4 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.6 KFO96504.1 - 3.6e-26 90.6 11.8 2.2e-05 24.1 0.7 8.4 5 3 3 8 8 8 6 TPR repeat TPR_16 PF13432.6 KFO96504.1 - 1.7e-21 76.5 0.1 7.7e-06 26.5 0.0 5.9 4 1 2 6 6 6 6 Tetratricopeptide repeat TPR_19 PF14559.6 KFO96504.1 - 4.6e-19 68.7 14.8 7.1e-07 29.6 0.6 6.7 2 1 3 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFO96504.1 - 1e-17 64.2 14.0 0.0011 19.3 0.0 7.5 5 3 2 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFO96504.1 - 7.7e-16 57.4 7.4 0.00017 22.1 0.0 8.4 4 3 4 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFO96504.1 - 3.3e-10 40.0 0.2 0.00026 21.1 0.2 4.5 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFO96504.1 - 1.1e-08 34.5 8.5 3.5 7.9 0.1 7.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFO96504.1 - 1.3e-08 34.9 12.2 0.087 13.5 0.2 7.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFO96504.1 - 7.3e-07 28.9 16.8 0.44 10.5 0.0 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO96504.1 - 3.2e-06 27.3 7.0 0.066 13.4 0.3 4.5 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 KFO96504.1 - 0.00024 20.2 7.9 0.045 12.7 0.5 3.0 1 1 1 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) DUF2929 PF11151.8 KFO96504.1 - 0.079 13.3 0.1 0.079 13.3 0.1 2.4 2 0 0 2 2 1 0 Protein of unknown function (DUF2929) TPR_15 PF13429.6 KFO96504.1 - 0.1 11.8 10.2 0.039 13.2 4.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat Coatomer_E PF04733.14 KFO96504.1 - 0.14 11.6 3.0 1.3 8.4 0.1 3.1 3 0 0 3 3 3 0 Coatomer epsilon subunit Fis1_TPR_C PF14853.6 KFO96504.1 - 0.14 12.2 2.7 21 5.3 0.0 4.2 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Wzy_C_2 PF11846.8 KFO96504.1 - 1.7 8.5 6.5 0.33 10.9 0.1 2.9 4 0 0 4 4 3 0 Virulence factor membrane-bound polymerase, C-terminal PMT_2 PF13231.6 KFO96504.1 - 2.3 8.4 15.9 0.022 15.0 6.6 2.3 2 1 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase B_solenoid_dext PF18841.1 KFO96505.1 - 2.1 8.7 8.8 1.6e+03 -0.5 8.8 3.2 1 1 0 1 1 1 0 Beta solenoid repeat from Dextranase SCF PF02404.15 KFO96506.1 - 1.7e-141 470.4 2.1 1.9e-141 470.2 2.1 1.0 1 0 0 1 1 1 1 Stem cell factor Elf1 PF05129.13 KFO96506.1 - 0.56 10.3 2.8 3.4 7.8 0.7 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Yae1_N PF09811.9 KFO96508.1 - 5.4e-18 64.4 63.4 1.8e+04 -28.2 63.4 6.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal DSPc PF00782.20 KFO96509.1 - 2.5e-43 147.1 0.0 3.5e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFO96509.1 - 0.00032 20.4 0.0 0.00047 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 KFO96509.1 - 0.00035 21.1 0.0 0.00069 20.1 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Init_tRNA_PT PF04179.12 KFO96509.1 - 0.013 15.8 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 KFO96509.1 - 0.082 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate WD40 PF00400.32 KFO96510.1 - 1.2e-50 168.4 20.4 3.2e-09 37.3 0.0 6.4 7 0 0 7 7 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO96510.1 - 7.6e-22 77.4 0.1 0.0017 18.6 0.0 5.5 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFO96510.1 - 8e-11 41.5 0.2 0.11 11.4 0.0 5.0 1 1 4 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFO96510.1 - 1.1e-08 35.2 0.4 2.8e-05 24.1 0.0 3.9 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KFO96510.1 - 8.1e-06 24.8 3.0 1.3 7.6 0.0 4.8 3 2 2 5 5 5 2 Nucleoporin Nup120/160 PD40 PF07676.12 KFO96510.1 - 0.00054 19.8 0.3 2.8 8.0 0.0 4.2 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 KFO96510.1 - 0.00056 19.5 0.3 1.6 8.5 0.0 3.8 4 0 0 4 4 4 2 Proteasome subunit A N-terminal signature WD40_like PF17005.5 KFO96510.1 - 0.0014 18.0 0.0 3 7.1 0.0 3.4 2 1 2 4 4 4 2 WD40-like domain Cytochrom_D1 PF02239.16 KFO96510.1 - 0.0035 15.9 0.1 2.9 6.3 0.0 2.9 1 1 1 3 3 3 2 Cytochrome D1 heme domain Frtz PF11768.8 KFO96510.1 - 0.023 13.1 0.0 13 4.0 0.0 3.0 1 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF4908 PF16252.5 KFO96510.1 - 0.023 14.2 0.0 0.08 12.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4908) CHAP PF05257.16 KFO96510.1 - 0.046 14.3 0.8 9.8 6.8 0.1 3.3 3 1 1 4 4 4 0 CHAP domain nos_propeller PF18764.1 KFO96510.1 - 0.059 13.3 0.3 58 3.7 0.0 4.0 4 1 0 4 4 4 0 Nitrous oxide reductase propeller repeat Glycos_transf_2 PF00535.26 KFO96511.1 - 1.4e-34 119.4 0.0 2.3e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFO96511.1 - 4.5e-09 36.6 0.0 6.9e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 KFO96511.1 - 3.1e-05 24.0 0.0 6.5e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KFO96511.1 - 4e-05 23.2 0.0 9.3e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KFO96511.1 - 0.0046 16.5 0.0 0.011 15.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Cation_ATPase_C PF00689.21 KFO96512.1 - 4.5e-45 153.6 3.8 4.5e-45 153.6 3.8 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KFO96512.1 - 8.7e-34 116.6 14.6 1.6e-25 89.7 1.7 2.9 3 0 0 3 3 3 2 E1-E2 ATPase ATP_Ca_trans_C PF12424.8 KFO96512.1 - 1.1e-28 99.4 3.7 2.9e-14 53.3 1.5 2.8 1 1 1 2 2 2 2 Plasma membrane calcium transporter ATPase C terminal Cation_ATPase PF13246.6 KFO96512.1 - 1.7e-17 63.3 0.0 4.4e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFO96512.1 - 1.1e-15 57.0 0.0 6.7e-15 54.5 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KFO96512.1 - 7.9e-14 52.4 0.0 2.9e-10 40.8 0.1 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFO96512.1 - 4.2e-07 30.0 1.3 6.7e-05 22.7 0.5 2.8 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase LRR_8 PF13855.6 KFO96514.1 - 7.5e-22 76.9 9.5 1.2e-11 44.2 0.8 3.8 3 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFO96514.1 - 6e-09 36.0 16.9 0.0099 16.3 0.1 4.7 1 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFO96514.1 - 6.3e-07 29.1 6.9 4.2e-05 23.1 1.9 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_5 PF13306.6 KFO96514.1 - 1.3e-06 28.3 0.3 6.7e-05 22.9 0.0 2.6 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRRNT PF01462.18 KFO96514.1 - 1.6e-05 24.5 2.8 1.6e-05 24.5 2.8 2.6 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KFO96514.1 - 3.4e-05 23.8 9.1 2.3 9.1 1.5 6.1 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.6 KFO96514.1 - 0.018 15.1 7.5 22 5.4 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich repeat LRR_8 PF13855.6 KFO96515.1 - 1.7e-32 111.0 32.2 7.8e-11 41.6 6.4 6.9 3 2 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 KFO96515.1 - 2.3e-20 72.3 28.7 5.4e-05 23.5 1.1 7.3 5 2 1 7 7 7 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFO96515.1 - 1.6e-08 33.9 13.1 1.1 9.5 0.3 7.4 7 0 0 7 7 7 3 Leucine Rich repeat LRR_9 PF14580.6 KFO96515.1 - 1.1e-06 28.3 12.3 0.0012 18.4 5.8 4.3 1 1 3 4 4 4 3 Leucine-rich repeat LRRNT PF01462.18 KFO96515.1 - 3.5e-06 26.5 6.5 9.4e-06 25.2 4.3 2.7 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.6 KFO96515.1 - 1.9e-05 24.6 2.0 0.018 15.0 0.0 3.0 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) CRT10 PF08728.10 KFO96515.1 - 0.0016 16.7 0.0 0.0024 16.1 0.0 1.2 1 0 0 1 1 1 1 CRT10 LRR_1 PF00560.33 KFO96515.1 - 0.025 15.1 30.6 18 6.4 0.2 10.5 10 2 0 10 10 10 0 Leucine Rich Repeat LRR_8 PF13855.6 KFO96516.1 - 1.1e-36 124.4 33.7 6.2e-10 38.7 1.8 7.0 3 1 4 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 KFO96516.1 - 4.4e-25 87.3 38.0 5.6e-06 26.6 3.5 7.4 2 1 7 9 9 9 9 Leucine Rich repeats (2 copies) LRRNT PF01462.18 KFO96516.1 - 4.3e-08 32.6 2.5 4.3e-08 32.6 2.5 2.5 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 KFO96516.1 - 5.1e-08 32.6 9.9 0.0065 16.0 0.6 3.3 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 KFO96516.1 - 1.9e-07 30.6 33.2 0.017 15.1 0.0 8.4 10 0 0 10 10 10 5 Leucine Rich repeat LRR_1 PF00560.33 KFO96516.1 - 3.2e-07 30.0 26.8 7.3 7.6 0.0 10.4 8 3 0 8 8 8 2 Leucine Rich Repeat LRR_5 PF13306.6 KFO96516.1 - 1.3e-06 28.4 4.4 0.00096 19.1 0.2 3.4 2 2 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) DUF4292 PF14125.6 KFO96516.1 - 0.061 13.0 3.0 6.5 6.4 0.1 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF4292) LRR_8 PF13855.6 KFO96517.1 - 1.6e-37 127.1 22.3 4.6e-15 55.1 3.1 4.3 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFO96517.1 - 1.3e-21 76.3 26.0 3.1e-05 24.3 2.8 6.2 1 1 7 8 8 8 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFO96517.1 - 7.7e-13 48.3 6.0 5.1e-05 22.9 2.9 3.1 1 1 2 3 3 3 3 Leucine-rich repeat LRR_5 PF13306.6 KFO96517.1 - 1.6e-11 44.3 3.7 1.9e-05 24.6 0.4 3.1 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRRNT PF01462.18 KFO96517.1 - 3.4e-07 29.8 4.8 3.4e-07 29.8 4.8 2.7 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KFO96517.1 - 1.9e-05 24.6 16.4 11 7.0 0.1 8.0 8 0 0 8 8 8 3 Leucine Rich Repeat GPS2_interact PF15784.5 KFO96517.1 - 0.025 15.0 0.2 0.043 14.3 0.2 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain LRR_6 PF13516.6 KFO96517.1 - 0.2 11.8 21.1 3.1 8.1 0.0 7.0 7 0 0 7 7 7 0 Leucine Rich repeat FNIP PF05725.12 KFO96517.1 - 0.5 10.6 6.2 5.8 7.2 0.3 3.4 2 1 0 2 2 2 0 FNIP Repeat BTG PF07742.12 KFO96518.1 - 7.1e-31 106.5 0.0 9e-31 106.1 0.0 1.1 1 0 0 1 1 1 1 BTG family RhoGEF PF00621.20 KFO96519.1 - 1.1e-18 68.1 4.8 2.4e-18 67.0 4.8 1.6 1 0 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 KFO96519.1 - 1.5e-09 37.8 0.6 0.00051 19.9 0.2 3.0 3 0 0 3 3 3 2 Pleckstrin homology domain PH_16 PF17838.1 KFO96519.1 - 4.8e-05 23.2 4.3 0.021 14.6 0.1 2.9 3 1 0 3 3 3 2 PH domain PH_5 PF15405.6 KFO96519.1 - 0.00073 19.7 5.1 0.002 18.2 0.4 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KFO96519.1 - 0.052 14.0 2.0 0.15 12.5 0.7 2.5 2 1 0 2 2 2 0 PH domain FYVE PF01363.21 KFO96520.1 - 2.9e-20 72.2 10.7 2.9e-20 72.2 10.7 2.6 2 0 0 2 2 2 1 FYVE zinc finger CENP-F_leu_zip PF10473.9 KFO96520.1 - 0.0016 18.5 20.2 0.0016 18.5 20.2 14.6 3 3 11 15 15 15 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IBR PF01485.21 KFO96520.1 - 0.013 15.7 5.3 0.073 13.3 5.3 2.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain B2 PF11473.8 KFO96520.1 - 3 7.7 6.9 30 4.5 0.0 4.8 4 0 0 4 4 4 0 RNA binding protein B2 zf-RING_2 PF13639.6 KFO96520.1 - 5 7.5 12.6 4.1 7.8 9.6 2.4 2 0 0 2 2 2 0 Ring finger domain Filament PF00038.21 KFO96520.1 - 6.2 6.3 284.8 0.048 13.2 62.2 11.1 1 1 8 9 9 9 0 Intermediate filament protein Lipase_GDSL_2 PF13472.6 KFO96521.1 - 0.00085 19.8 0.0 0.0031 18.0 0.0 1.9 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 KFO96521.1 - 0.0048 16.2 0.0 0.0089 15.3 0.0 1.3 1 0 0 1 1 1 1 OSK domain Tmemb_cc2 PF10267.9 KFO96521.1 - 0.065 12.4 0.5 0.094 11.8 0.5 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Lipase_GDSL PF00657.22 KFO96521.1 - 0.22 11.5 0.0 0.85 9.6 0.0 1.9 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase NUDIX PF00293.28 KFO96522.1 - 2.8e-16 59.7 0.4 3.3e-16 59.5 0.4 1.1 1 0 0 1 1 1 1 NUDIX domain Biopterin_H PF00351.21 KFO96523.1 - 3.6e-175 581.8 0.1 4.3e-175 581.5 0.1 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase Peptidase_M1 PF01433.20 KFO96524.1 - 1.2e-81 273.5 0.9 2.1e-81 272.6 0.9 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KFO96524.1 - 2.6e-77 260.5 3.6 4.5e-77 259.7 3.6 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KFO96524.1 - 6.9e-29 101.4 0.4 1.2e-28 100.5 0.4 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain dUTPase PF00692.19 KFO96525.1 - 1.7e-18 66.5 0.1 2.5e-18 66.0 0.1 1.2 1 0 0 1 1 1 1 dUTPase RVP PF00077.20 KFO96525.1 - 0.017 15.4 0.1 0.042 14.2 0.1 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease THP2 PF09432.10 KFO96527.1 - 0.047 13.7 0.1 0.062 13.3 0.1 1.2 1 0 0 1 1 1 0 Tho complex subunit THP2 Cohesin_HEAT PF12765.7 KFO96528.1 - 1.5e-13 50.8 0.2 2.3e-13 50.2 0.2 1.3 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 KFO96528.1 - 7.6e-06 25.8 0.5 0.0025 17.9 0.0 2.3 2 0 0 2 2 2 2 HEAT repeat HEAT_EZ PF13513.6 KFO96528.1 - 0.00053 20.4 0.2 0.0091 16.5 0.1 2.2 1 1 1 2 2 2 1 HEAT-like repeat Cnd3 PF12719.7 KFO96528.1 - 0.0013 18.0 0.1 0.055 12.7 0.0 2.0 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain DUF3385 PF11865.8 KFO96528.1 - 0.079 12.9 0.0 0.081 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) CcmH PF03918.14 KFO96528.1 - 0.097 12.0 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein CLASP_N PF12348.8 KFO96528.1 - 0.15 11.6 0.0 0.29 10.6 0.0 1.5 1 1 0 1 1 1 0 CLASP N terminal Nipped-B_C PF12830.7 KFO96529.1 - 9.5e-69 231.2 1.3 3.4e-68 229.3 1.3 2.0 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus DNA_repr_REX1B PF14966.6 KFO96529.1 - 0.019 15.6 0.0 0.061 14.0 0.0 1.9 1 0 0 1 1 1 0 DNA repair REX1-B AP3D1 PF06375.11 KFO96529.1 - 0.035 14.4 10.8 0.58 10.4 0.4 2.6 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Cnd1 PF12717.7 KFO96529.1 - 0.099 12.7 3.9 2.3 8.3 0.0 3.4 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 T3SS_basalb_I PF17001.5 KFO96529.1 - 0.3 11.7 8.6 0.7 10.5 2.0 3.6 3 0 0 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI DTHCT PF08070.11 KFO96529.1 - 0.48 11.2 13.7 0.084 13.6 8.4 2.6 2 0 0 2 2 2 0 DTHCT (NUC029) region DUF3453 PF11935.8 KFO96530.1 - 4.9e-49 167.0 0.0 7.5e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) Symplekin_C PF12295.8 KFO96530.1 - 6.3e-12 46.0 0.1 1.5e-11 44.7 0.1 1.7 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal Claudin_2 PF13903.6 KFO96531.1 - 4.9e-10 39.5 6.0 5.9e-10 39.2 6.0 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFO96531.1 - 0.00037 20.4 5.1 0.00052 19.9 5.1 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF2347 PF09804.9 KFO96532.1 - 9e-73 245.3 0.0 1.2e-72 244.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 KFO96532.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KFO96532.1 - 3.2e-09 36.0 2.2 0.00035 19.4 0.2 3.2 2 1 0 2 2 2 2 Transport protein Avl9 Baculo_LEF-11 PF06385.12 KFO96532.1 - 0.067 13.7 0.8 0.13 12.8 0.8 1.4 1 0 0 1 1 1 0 Baculovirus LEF-11 protein Pkinase PF00069.25 KFO96533.1 - 1.6e-51 175.2 0.0 2.1e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO96533.1 - 1.6e-22 80.1 0.0 2.7e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FYDLN_acid PF09538.10 KFO96533.1 - 0.032 14.9 0.2 0.032 14.9 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF2116 PF09889.9 KFO96533.1 - 0.069 13.1 0.3 0.14 12.1 0.3 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) SSB PF00436.25 KFO96534.1 - 9.5e-32 109.1 0.2 1.1e-31 108.9 0.2 1.1 1 0 0 1 1 1 1 Single-strand binding protein family bZIP_1 PF00170.21 KFO96535.1 - 5.6e-15 55.2 16.0 1.3e-14 54.0 16.0 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFO96535.1 - 4.9e-09 36.1 10.8 4.9e-09 36.1 10.8 2.4 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFO96535.1 - 1.4e-06 28.7 10.7 3e-06 27.6 10.7 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor ZapB PF06005.12 KFO96535.1 - 0.005 17.3 3.1 0.019 15.4 3.1 2.1 1 0 0 1 1 1 1 Cell division protein ZapB Fmp27_WPPW PF10359.9 KFO96535.1 - 0.0076 15.2 0.3 0.01 14.7 0.3 1.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain HAUS6_N PF14661.6 KFO96535.1 - 0.012 15.2 1.3 0.069 12.7 2.3 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Goodbye PF17109.5 KFO96535.1 - 0.016 15.7 0.5 0.038 14.4 0.5 1.7 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain TPR_MLP1_2 PF07926.12 KFO96535.1 - 0.043 13.9 10.5 0.08 13.0 10.5 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.11 KFO96535.1 - 0.048 14.1 2.0 0.14 12.6 2.0 1.8 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Jnk-SapK_ap_N PF09744.9 KFO96535.1 - 0.049 13.9 7.5 0.096 12.9 7.5 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 HAUS-augmin3 PF14932.6 KFO96535.1 - 0.06 12.9 5.5 0.12 11.9 5.5 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 APG6_N PF17675.1 KFO96535.1 - 0.076 13.6 6.5 0.18 12.3 6.5 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region JMY PF15871.5 KFO96535.1 - 0.076 12.3 5.7 0.12 11.7 5.7 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF724 PF05266.14 KFO96535.1 - 0.22 11.3 7.0 0.38 10.6 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ADIP PF11559.8 KFO96535.1 - 0.23 11.5 11.0 0.38 10.8 11.0 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding FOXP-CC PF16159.5 KFO96535.1 - 0.24 12.1 1.7 0.59 10.8 1.7 1.7 1 0 0 1 1 1 0 FOXP coiled-coil domain TBCA PF02970.16 KFO96535.1 - 0.27 11.6 7.4 0.57 10.6 7.4 1.5 1 0 0 1 1 1 0 Tubulin binding cofactor A DUF4404 PF14357.6 KFO96535.1 - 0.63 10.7 5.0 1.2 9.8 2.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF1664 PF07889.12 KFO96535.1 - 1 9.4 4.5 1.6 8.8 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DAGK_acc PF00609.19 KFO96536.1 - 1.1e-47 162.4 0.0 2.2e-47 161.4 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KFO96536.1 - 3.2e-28 97.9 0.0 7.5e-28 96.7 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 KFO96536.1 - 2.5e-15 56.1 27.6 1.9e-11 43.7 15.3 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Ank_2 PF12796.7 KFO96536.1 - 1.6e-12 47.8 0.2 3.5e-12 46.7 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFO96536.1 - 2.2e-09 37.6 0.0 8.5e-07 29.4 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFO96536.1 - 1.9e-08 34.4 0.1 0.0013 19.0 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFO96536.1 - 1.1e-07 31.5 1.0 0.02 15.4 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KFO96536.1 - 1.7e-05 25.1 0.3 0.026 15.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat RVT_1 PF00078.27 KFO96536.1 - 0.02 14.4 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PHD_2 PF13831.6 KFO96536.1 - 4.7 6.9 10.0 3.1 7.4 1.1 2.8 2 0 0 2 2 2 0 PHD-finger PTN_MK_C PF01091.18 KFO96537.1 - 9.5e-28 96.4 9.4 9.5e-28 96.4 9.4 2.9 2 1 1 3 3 3 1 PTN/MK heparin-binding protein family, C-terminal domain PTN_MK_N PF05196.13 KFO96537.1 - 2.7e-26 91.6 17.0 2.7e-26 91.6 17.0 2.7 3 1 0 3 3 3 1 PTN/MK heparin-binding protein family, N-terminal domain OAD_gamma PF04277.13 KFO96537.1 - 1.5 9.5 4.7 2.1 9.0 0.1 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain UPF0239 PF06783.11 KFO96537.1 - 2.2 8.5 8.0 4.6 7.5 0.0 2.6 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0239) 7tm_1 PF00001.21 KFO96538.1 - 7.7e-74 248.3 5.0 1.1e-73 247.8 5.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFO96538.1 - 1.3e-06 28.4 3.6 1.3e-06 28.4 3.6 2.3 3 0 0 3 3 3 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFO96538.1 - 1.6e-06 27.9 10.9 1.6e-06 27.9 10.9 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF3697 PF12478.8 KFO96539.1 - 1.3e-16 60.3 0.5 1.3e-16 60.3 0.5 2.0 2 0 0 2 2 2 1 Ubiquitin-associated protein 2 UBA_4 PF14555.6 KFO96539.1 - 7.5e-05 22.5 0.0 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain DUF1296 PF06972.11 KFO96539.1 - 0.0085 16.2 0.1 0.016 15.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1296) UBA PF00627.31 KFO96539.1 - 0.018 14.9 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain DUF1510 PF07423.11 KFO96539.1 - 0.051 13.7 0.1 0.051 13.7 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1510) CUE PF02845.16 KFO96539.1 - 0.053 13.2 0.1 0.16 11.7 0.1 1.8 1 0 0 1 1 1 0 CUE domain API5 PF05918.11 KFO96539.1 - 6.7 5.4 5.6 12 4.6 5.6 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) UQ_con PF00179.26 KFO96540.1 - 6.9e-30 103.5 0.3 8.7e-30 103.2 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme 7tm_4 PF13853.6 KFO96541.1 - 5e-07 29.7 1.4 6.5e-07 29.4 1.4 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO96541.1 - 1.3e-05 24.7 0.6 1.8e-05 24.2 0.2 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) GRIP PF01465.20 KFO96543.1 - 9.8e-17 60.6 0.0 3.3e-16 58.9 0.0 2.0 1 0 0 1 1 1 1 GRIP domain BING4CT PF08149.11 KFO96543.1 - 0.28 11.0 1.8 2.3 8.1 0.3 2.9 2 1 0 2 2 2 0 BING4CT (NUC141) domain EDR1 PF14381.6 KFO96543.1 - 1.6 8.4 13.1 0.34 10.6 0.1 3.2 3 0 0 3 3 3 0 Ethylene-responsive protein kinase Le-CTR1 DUF3584 PF12128.8 KFO96543.1 - 2.5 5.5 81.2 0.2 9.2 16.3 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3584) Fez1 PF06818.15 KFO96543.1 - 8.6 6.8 86.1 1.6 9.1 0.8 5.0 2 1 3 5 5 5 0 Fez1 SPA PF08616.10 KFO96544.1 - 2.8e-14 53.0 0.0 7e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis DENN PF02141.21 KFO96544.1 - 7e-06 26.1 4.5 7e-06 26.1 4.5 2.5 2 1 0 2 2 2 1 DENN (AEX-3) domain Avl9 PF09794.9 KFO96544.1 - 0.00037 19.3 0.0 0.00059 18.7 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 SBF2 PF12335.8 KFO96545.1 - 2.5e-109 364.3 4.9 4.1e-109 363.6 4.9 1.4 1 0 0 1 1 1 1 Myotubularin protein Myotub-related PF06602.14 KFO96545.1 - 4.4e-83 279.1 0.0 7.5e-83 278.4 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DENN PF02141.21 KFO96545.1 - 7.7e-53 179.2 0.3 1.7e-52 178.1 0.3 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain GRAM PF02893.20 KFO96545.1 - 9.8e-21 73.8 0.0 6.8e-20 71.0 0.0 2.3 2 0 0 2 2 2 1 GRAM domain uDENN PF03456.18 KFO96545.1 - 1.2e-18 67.6 1.7 3.9e-18 66.0 1.7 2.0 1 0 0 1 1 1 1 uDENN domain PH PF00169.29 KFO96545.1 - 8.8e-14 51.9 0.1 2.3e-13 50.5 0.1 1.8 1 0 0 1 1 1 1 PH domain dDENN PF03455.19 KFO96545.1 - 1.4e-07 31.4 0.0 5.8e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 dDENN domain SPA PF08616.10 KFO96545.1 - 7e-05 22.8 0.0 0.00019 21.3 0.0 1.8 1 0 0 1 1 1 1 Stabilization of polarity axis PH_11 PF15413.6 KFO96545.1 - 0.0069 16.8 0.5 0.039 14.4 0.5 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.10 KFO96545.1 - 0.046 14.1 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Plant pleckstrin homology-like region IpaB_EvcA PF03278.13 KFO96545.1 - 0.096 12.4 0.2 0.27 10.9 0.2 1.7 1 0 0 1 1 1 0 IpaB/EvcA family PH_9 PF15410.6 KFO96545.1 - 0.16 12.3 0.6 5.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain SWIRM-assoc_2 PF16496.5 KFO96546.1 - 6.5e-156 519.4 8.8 6.5e-156 519.4 8.8 2.3 2 1 0 2 2 2 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 KFO96546.1 - 4.1e-31 107.2 2.0 6.7e-31 106.5 0.1 2.4 3 0 0 3 3 3 1 SWIRM domain SWIRM-assoc_3 PF16498.5 KFO96546.1 - 8.3e-31 106.1 1.3 8.3e-31 106.1 1.3 2.8 2 1 0 2 2 2 1 SWIRM-associated domain at the C-terminal SWIRM-assoc_1 PF16495.5 KFO96546.1 - 6.1e-29 99.8 19.8 6.1e-29 99.8 19.8 2.6 3 0 0 3 3 3 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KFO96546.1 - 1.3e-12 47.7 0.2 2.8e-12 46.6 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFO96546.1 - 1.3e-07 31.8 0.0 4.5e-07 30.0 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Chromo PF00385.24 KFO96546.1 - 0.058 13.3 0.3 0.16 11.9 0.3 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF2618 PF10940.8 KFO96546.1 - 0.15 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) DUF919 PF06034.11 KFO96546.1 - 0.26 11.1 8.2 0.11 12.4 5.2 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Helicase_C PF00271.31 KFO96547.1 - 2.1e-13 50.6 0.0 4.9e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 KFO96547.1 - 2.7e-13 50.1 0.0 7.7e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) dsrm PF00035.26 KFO96547.1 - 4.2e-11 43.4 2.3 7.9e-06 26.5 0.6 2.5 2 0 0 2 2 2 2 Double-stranded RNA binding motif OB_NTP_bind PF07717.16 KFO96547.1 - 6.2e-08 32.9 0.0 1.5e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KFO96547.1 - 3.3e-06 27.0 0.0 6.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Dicer_dimer PF03368.14 KFO96547.1 - 9.4e-05 22.5 0.3 0.025 14.7 0.1 3.3 3 0 0 3 3 3 1 Dicer dimerisation domain AAA_19 PF13245.6 KFO96547.1 - 0.00077 19.8 0.0 0.0028 18.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFO96547.1 - 0.011 16.0 0.0 0.035 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KFO96547.1 - 0.059 12.8 0.0 0.69 9.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.27 KFO96547.1 - 0.16 12.5 0.0 0.6 10.6 0.0 2.0 1 0 0 1 1 1 0 ABC transporter Tubulin-binding PF00418.19 KFO96548.1 - 6.7e-50 166.8 22.7 2.2e-17 62.8 4.8 3.1 3 0 0 3 3 3 3 Tau and MAP protein, tubulin-binding repeat SBP_bac_3 PF00497.20 KFO96552.1 - 0.00049 19.6 0.0 0.00063 19.2 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 KFO96552.1 - 0.0011 18.8 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel CSD PF00313.22 KFO96554.1 - 1e-17 63.7 0.1 2.2e-17 62.7 0.1 1.6 1 1 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-CCHC PF00098.23 KFO96554.1 - 8.8e-07 28.7 13.7 6.8e-05 22.8 2.7 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 KFO96554.1 - 0.021 14.5 10.5 0.15 11.8 1.6 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 KFO96554.1 - 0.17 11.8 6.8 2.3 8.1 1.2 2.6 2 0 0 2 2 2 0 Zinc knuckle Popeye PF04831.13 KFO96555.1 - 5.4e-98 324.7 10.7 4e-51 172.9 2.1 2.1 2 0 0 2 2 2 2 Popeye protein conserved region cNMP_binding PF00027.29 KFO96555.1 - 7.6e-06 25.9 0.0 0.048 13.7 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Rdx PF10262.9 KFO96555.1 - 0.03 14.5 0.0 2.7 8.2 0.0 2.6 2 1 0 2 2 2 0 Rdx family Peptidase_S9_N PF02897.15 KFO96556.1 - 3.2e-144 480.8 0.0 3.8e-144 480.5 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 KFO96556.1 - 2.1e-68 230.0 0.0 3.2e-68 229.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KFO96556.1 - 0.077 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative esterase APG5 PF04106.12 KFO96557.1 - 1.3e-61 208.1 0.5 1.6e-61 207.8 0.5 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Crystall PF00030.19 KFO96559.1 - 3.1e-126 411.8 1.3 2e-28 98.4 0.0 6.4 6 0 0 6 6 6 6 Beta/Gamma crystallin IL4_i_Ig PF18258.1 KFO96559.1 - 8.1e-19 67.6 6.4 0.013 15.6 0.1 9.0 5 4 5 10 10 10 5 Interleukin-4 inducing immunoglobulin-binding domain Ricin_B_lectin PF00652.22 KFO96559.1 - 1.7e-10 41.2 0.0 3.2e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Inhibitor_I36 PF03995.13 KFO96559.1 - 0.0014 18.5 0.1 1.2 9.1 0.0 4.9 5 1 0 5 5 5 1 Peptidase inhibitor family I36 ADH_zinc_N_2 PF13602.6 KFO96560.1 - 1.6e-23 84.2 0.0 2.5e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFO96560.1 - 4e-15 56.0 0.1 8.7e-15 54.8 0.1 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFO96560.1 - 1.4e-09 37.8 0.0 6.6e-09 35.6 0.0 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 KFO96560.1 - 0.0057 16.4 0.2 0.0096 15.7 0.2 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase adh_short PF00106.25 KFO96560.1 - 0.018 14.5 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase THF_DHG_CYH_C PF02882.19 KFO96560.1 - 0.046 13.0 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 KFO96560.1 - 0.05 13.4 0.1 0.096 12.5 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Amidase PF01425.21 KFO96561.1 - 3.4e-129 431.7 0.0 1.6e-128 429.5 0.0 1.8 1 1 0 1 1 1 1 Amidase FAM176 PF14851.6 KFO96562.1 - 0.058 13.1 2.1 0.09 12.4 2.1 1.3 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 KFO96562.1 - 1.3 9.4 6.8 2.8 8.4 6.8 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BEN PF10523.9 KFO96563.1 - 4.8e-73 241.4 4.1 1.7e-20 73.0 0.0 4.5 4 0 0 4 4 4 4 BEN domain FAA_hydrolase PF01557.18 KFO96565.1 - 6.3e-22 78.3 0.0 6.9e-22 78.2 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family polyprenyl_synt PF00348.17 KFO96566.1 - 1.3e-19 70.2 0.1 2.1e-19 69.6 0.1 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase VirK PF06903.12 KFO96566.1 - 0.017 15.2 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 VirK protein Yae1_N PF09811.9 KFO96567.1 - 2.8e-10 39.7 30.7 1.4e+02 2.3 30.7 3.6 1 1 0 1 1 1 1 Essential protein Yae1, N terminal SOBP PF15279.6 KFO96568.1 - 3.4e-91 307.2 39.9 3.4e-91 307.2 39.9 3.3 3 1 0 3 3 3 1 Sine oculis-binding protein zf-FCS PF06467.14 KFO96568.1 - 0.19 11.7 18.3 0.17 11.8 1.5 3.0 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-C6H2 PF15801.5 KFO96568.1 - 0.58 10.5 9.8 2 8.8 6.1 3.0 2 1 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding SLED PF12140.8 KFO96569.1 - 1.4e-34 119.0 0.5 2e-34 118.4 0.5 1.2 1 0 0 1 1 1 1 SLED domain SAM_1 PF00536.30 KFO96569.1 - 7e-15 55.2 0.1 1.2e-14 54.5 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RBR PF17208.3 KFO96569.1 - 6e-13 49.3 7.0 1.5e-12 48.0 7.0 1.8 1 0 0 1 1 1 1 RNA binding Region SAM_2 PF07647.17 KFO96569.1 - 0.0005 20.1 0.0 0.00084 19.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFO96569.1 - 0.0062 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Sec63 PF02889.16 KFO96570.1 - 4.2e-20 72.0 2.7 3.7e-09 36.1 0.6 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DnaJ PF00226.31 KFO96570.1 - 3.3e-17 62.4 0.0 9e-17 61.0 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain PglZ PF08665.12 KFO96570.1 - 0.23 11.6 2.1 0.28 11.3 0.6 1.9 1 1 0 1 1 1 0 PglZ domain OSTMP1 PF09777.9 KFO96571.1 - 1.1e-77 260.6 5.9 1.2e-77 260.5 5.9 1.0 1 0 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor CECR6_TMEM121 PF14997.6 KFO96571.1 - 0.00072 19.4 0.0 0.00091 19.1 0.0 1.2 1 0 0 1 1 1 1 CECR6/TMEM121 family Hormone_recep PF00104.30 KFO96572.1 - 1.9e-34 119.0 0.0 2.6e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFO96572.1 - 5.2e-29 100.5 14.0 1.8e-28 98.8 13.8 2.0 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) PX PF00787.24 KFO96573.1 - 2e-22 79.3 0.2 2.2e-22 79.2 0.2 1.1 1 0 0 1 1 1 1 PX domain RdRP_1 PF00680.20 KFO96573.1 - 0.033 12.7 0.0 0.036 12.6 0.0 1.0 1 0 0 1 1 1 0 RNA dependent RNA polymerase AFG1_ATPase PF03969.16 KFO96574.1 - 4.5e-114 381.1 3.0 5.9e-110 367.6 0.5 2.0 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 KFO96574.1 - 3.9e-05 24.1 0.1 0.011 16.2 0.1 2.8 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KFO96574.1 - 5.8e-05 23.5 0.1 0.00043 20.7 0.0 2.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFO96574.1 - 0.0007 19.9 0.0 0.0026 18.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KFO96574.1 - 0.0035 17.4 0.0 0.01 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KFO96574.1 - 0.0036 16.9 0.1 0.032 13.7 0.1 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain NACHT PF05729.12 KFO96574.1 - 0.0071 16.3 0.0 0.036 14.0 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.6 KFO96574.1 - 0.016 15.5 0.1 1.1 9.5 0.1 2.5 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KFO96574.1 - 0.028 13.7 0.0 0.06 12.6 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KFO96574.1 - 0.051 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 KFO96574.1 - 0.067 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mrx7 PF10906.8 KFO96574.1 - 0.085 13.1 0.5 0.25 11.6 0.1 2.0 2 0 0 2 2 2 0 MIOREX complex component 7 PA26 PF04636.13 KFO96575.1 - 4.9e-209 694.7 1.7 5.6e-209 694.5 1.7 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) CMD PF02627.20 KFO96575.1 - 0.00045 20.2 0.0 0.0013 18.7 0.0 1.8 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family 60KD_IMP PF02096.20 KFO96575.1 - 0.077 12.9 0.2 0.16 11.9 0.2 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein Cep57_CLD PF14073.6 KFO96576.1 - 3.6e-63 212.8 35.9 3.6e-63 212.8 35.9 2.8 3 1 0 3 3 3 1 Centrosome localisation domain of Cep57 Cep57_MT_bd PF06657.13 KFO96576.1 - 3e-20 72.4 1.7 3e-20 72.4 1.7 4.5 2 1 2 5 5 5 1 Centrosome microtubule-binding domain of Cep57 CENP-F_leu_zip PF10473.9 KFO96576.1 - 3 7.9 52.3 2.9 7.9 24.7 3.5 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MGC-24 PF05283.11 KFO96577.1 - 3.7e-31 108.4 8.6 3.7e-31 108.4 8.6 2.0 1 1 1 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Phostensin PF13914.6 KFO96577.1 - 0.051 14.2 2.6 0.062 13.9 2.6 1.1 1 0 0 1 1 1 0 Phostensin PP1-binding and SH3-binding region DUF4366 PF14283.6 KFO96577.1 - 0.072 13.1 0.0 0.11 12.6 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Pro_isomerase PF00160.21 KFO96578.1 - 1.6e-41 142.2 0.0 1.7e-41 142.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ADK PF00406.22 KFO96579.1 - 2.8e-19 69.7 0.0 4.9e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KFO96579.1 - 1.1e-14 55.0 0.0 2.4e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain FAP206 PF12018.8 KFO96579.1 - 2.3e-09 37.2 1.3 9.5e-07 28.6 0.0 3.2 2 1 1 3 3 3 1 Domain of unknown function YHS PF04945.13 KFO96579.1 - 7.8e-08 32.3 0.6 0.025 14.7 0.0 3.3 3 0 0 3 3 3 2 YHS domain AAA_18 PF13238.6 KFO96579.1 - 0.00041 20.9 0.1 0.0092 16.5 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KFO96579.1 - 0.0014 18.8 0.1 0.0046 17.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 KFO96579.1 - 0.0021 17.8 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 Cytidylate kinase AAA_28 PF13521.6 KFO96579.1 - 0.018 15.3 0.0 0.099 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KFO96579.1 - 0.02 14.6 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KFO96579.1 - 0.049 13.0 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 KFO96579.1 - 0.074 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFO96579.1 - 0.28 11.6 0.8 0.93 9.9 0.0 2.3 2 1 0 2 2 2 0 RNA helicase ADK PF00406.22 KFO96580.1 - 6.6e-14 52.3 0.1 5.5e-09 36.3 0.0 2.2 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 KFO96580.1 - 3.3e-13 50.2 0.0 8.4e-06 26.3 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_18 PF13238.6 KFO96580.1 - 2.6e-07 31.2 0.0 9.9e-07 29.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain FAP206 PF12018.8 KFO96580.1 - 0.00015 21.4 1.5 0.00033 20.3 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function YHS PF04945.13 KFO96580.1 - 0.00026 21.0 5.4 0.00029 20.9 3.0 2.2 1 1 1 2 2 2 1 YHS domain AAA_28 PF13521.6 KFO96580.1 - 0.00029 21.1 0.0 0.00068 19.9 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFO96580.1 - 0.0018 18.4 0.0 0.0055 16.9 0.0 1.8 2 1 0 2 2 2 1 AAA domain SKI PF01202.22 KFO96580.1 - 0.0021 18.2 0.0 0.0091 16.1 0.0 2.0 2 0 0 2 2 2 1 Shikimate kinase Thymidylate_kin PF02223.17 KFO96580.1 - 0.0023 17.6 0.4 2 8.0 0.1 2.5 2 0 0 2 2 2 2 Thymidylate kinase NACHT PF05729.12 KFO96580.1 - 0.0033 17.4 0.1 0.032 14.2 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 KFO96580.1 - 0.0043 17.5 0.0 0.0067 16.9 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KFO96580.1 - 0.01 15.9 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE G-alpha PF00503.20 KFO96580.1 - 0.013 14.6 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_24 PF13479.6 KFO96580.1 - 0.021 14.5 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFO96580.1 - 0.024 15.1 0.0 0.039 14.5 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 KFO96580.1 - 0.039 14.0 1.7 0.11 12.5 0.0 2.5 2 1 2 4 4 4 0 AAA domain Zeta_toxin PF06414.12 KFO96580.1 - 0.047 13.0 0.0 0.1 11.8 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 KFO96580.1 - 0.05 12.8 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.14 KFO96580.1 - 0.059 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) dNK PF01712.19 KFO96580.1 - 0.069 13.0 0.0 0.55 10.1 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase RNA_helicase PF00910.22 KFO96580.1 - 0.12 12.7 0.0 0.32 11.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ADK PF00406.22 KFO96581.1 - 2.3e-23 82.9 0.2 1.8e-20 73.6 0.0 2.5 2 0 0 2 2 2 1 Adenylate kinase AAA_17 PF13207.6 KFO96581.1 - 2.2e-15 57.3 2.0 2.2e-11 44.3 0.0 2.9 2 1 1 3 3 3 2 AAA domain AAA_18 PF13238.6 KFO96581.1 - 7e-10 39.6 3.6 2.4e-05 24.9 2.2 3.0 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 KFO96581.1 - 6.8e-07 29.8 0.1 0.031 14.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFO96581.1 - 2.7e-05 24.6 0.1 0.8 10.1 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 KFO96581.1 - 4.3e-05 23.7 0.0 0.0042 17.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 KFO96581.1 - 4.6e-05 23.8 5.0 0.49 10.6 0.0 3.0 2 1 0 2 2 2 2 Hydin Adenylate kinase-like domain ABC_tran PF00005.27 KFO96581.1 - 0.00013 22.5 1.8 0.37 11.3 0.0 3.2 3 0 0 3 3 3 1 ABC transporter NACHT PF05729.12 KFO96581.1 - 0.00048 20.1 0.1 0.0022 17.9 0.1 2.0 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 KFO96581.1 - 0.00054 20.2 5.1 0.55 10.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KFO96581.1 - 0.00063 20.0 0.1 0.78 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KFO96581.1 - 0.00085 19.1 0.0 0.25 11.1 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain SKI PF01202.22 KFO96581.1 - 0.00093 19.4 0.9 0.072 13.2 0.0 3.1 3 0 0 3 3 3 1 Shikimate kinase AAA_24 PF13479.6 KFO96581.1 - 0.00095 18.9 0.1 0.98 9.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFO96581.1 - 0.0012 19.2 0.0 1 9.8 0.0 2.9 2 0 0 2 2 2 1 RNA helicase FAP206 PF12018.8 KFO96581.1 - 0.0012 18.4 0.5 0.03 13.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function AAA_5 PF07728.14 KFO96581.1 - 0.0013 18.8 0.0 0.062 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Herpes_Helicase PF02689.14 KFO96581.1 - 0.0021 16.1 0.5 0.0038 15.2 0.0 1.6 2 0 0 2 2 2 1 Helicase Zeta_toxin PF06414.12 KFO96581.1 - 0.0036 16.6 0.0 0.23 10.7 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin NTPase_1 PF03266.15 KFO96581.1 - 0.0039 17.1 0.0 3.7 7.4 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 KFO96581.1 - 0.013 15.2 0.0 0.24 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain GEN1_C PF18380.1 KFO96581.1 - 0.014 16.3 6.5 0.025 15.5 6.5 1.5 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain RNase_H2_suC PF08615.11 KFO96581.1 - 0.014 15.5 0.9 0.021 15.0 0.9 1.3 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) MMR_HSR1 PF01926.23 KFO96581.1 - 0.018 15.1 0.0 10 6.3 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase KTI12 PF08433.10 KFO96581.1 - 0.02 14.4 6.5 2.8 7.3 3.7 2.7 2 1 0 2 2 2 0 Chromatin associated protein KTI12 Cytidylate_kin PF02224.18 KFO96581.1 - 0.036 13.8 0.0 8.9 6.0 0.0 2.6 2 1 0 2 2 2 0 Cytidylate kinase Thymidylate_kin PF02223.17 KFO96581.1 - 0.049 13.3 8.3 0.49 10.1 0.1 3.5 3 1 1 4 4 3 0 Thymidylate kinase AAA_11 PF13086.6 KFO96581.1 - 0.049 13.4 5.4 9 6.0 3.0 2.9 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 KFO96581.1 - 0.052 12.9 0.0 1.8 7.9 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KFO96581.1 - 0.056 13.5 0.2 17 5.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 KFO96581.1 - 0.07 12.9 0.0 16 5.2 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF4746 PF15928.5 KFO96581.1 - 0.074 12.5 9.8 0.13 11.7 9.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) cobW PF02492.19 KFO96581.1 - 0.098 12.2 0.0 3.2 7.3 0.0 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ZZ PF00569.17 KFO96581.1 - 0.15 11.9 0.1 0.34 10.8 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, ZZ type RXT2_N PF08595.11 KFO96581.1 - 0.15 12.1 6.7 0.29 11.1 6.7 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal AAA_19 PF13245.6 KFO96581.1 - 0.15 12.4 0.0 14 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KFO96581.1 - 0.16 11.9 0.0 0.35 10.7 0.0 1.5 2 0 0 2 2 1 0 P-loop Nucleotide Kinase3 AAA_29 PF13555.6 KFO96581.1 - 0.19 11.5 0.0 9.6 6.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRP54 PF00448.22 KFO96581.1 - 0.2 11.3 0.0 9 5.9 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain FAM176 PF14851.6 KFO96581.1 - 0.25 11.0 11.7 0.45 10.2 11.7 1.4 1 0 0 1 1 1 0 FAM176 family Connexin PF00029.19 KFO96581.1 - 0.26 11.0 1.6 0.39 10.5 1.6 1.2 1 0 0 1 1 1 0 Connexin NOA36 PF06524.12 KFO96581.1 - 0.34 10.2 9.4 0.54 9.5 9.4 1.2 1 0 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.14 KFO96581.1 - 0.54 10.0 9.1 0.91 9.3 9.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CPSF100_C PF13299.6 KFO96581.1 - 0.58 10.3 3.7 0.93 9.7 3.7 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4820 PF16091.5 KFO96581.1 - 0.61 9.4 4.0 1 8.7 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CENP-B_dimeris PF09026.10 KFO96581.1 - 0.72 10.3 9.9 1.5 9.2 9.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 KFO96581.1 - 1.6 6.7 13.0 2.2 6.2 13.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 KFO96581.1 - 1.8 7.7 6.7 2.8 7.1 6.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 KFO96581.1 - 2.1 6.6 9.7 2.7 6.2 9.7 1.1 1 0 0 1 1 1 0 CDC45-like protein ATP_bind_1 PF03029.17 KFO96581.1 - 2.3 7.9 4.2 14 5.4 0.0 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein DUF3464 PF11947.8 KFO96581.1 - 3.7 7.3 4.7 6.1 6.6 4.7 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4637 PF15470.6 KFO96581.1 - 5.2 6.8 14.4 11 5.8 14.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) MDM10 PF12519.8 KFO96581.1 - 9.9 4.9 6.0 14 4.4 6.0 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Syja_N PF02383.18 KFO96582.1 - 2.1e-73 247.5 0.0 4e-73 246.5 0.0 1.5 1 0 0 1 1 1 1 SacI homology domain 7tm_1 PF00001.21 KFO96583.1 - 4.2e-34 118.1 17.9 5.2e-34 117.8 17.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFO96583.1 - 3.9e-05 23.5 15.5 0.00058 19.7 15.5 2.5 1 1 0 1 1 1 1 Olfactory receptor WH2 PF02205.20 KFO96584.1 - 1.8e-07 30.7 0.1 3e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 WH2 motif WD40 PF00400.32 KFO96585.1 - 6.4e-37 124.9 11.9 2.3e-06 28.2 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO96585.1 - 5.7e-11 42.6 0.2 0.0093 16.2 0.1 4.9 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFO96585.1 - 0.0063 16.4 0.5 2.4 8.0 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 KFO96585.1 - 0.065 12.8 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 PQQ-like domain Methyltransf_22 PF13383.6 KFO96586.1 - 2.3e-12 47.0 0.5 2.6e-12 46.9 0.5 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 KFO96586.1 - 1.9e-07 31.2 0.0 2.8e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain DAO PF01266.24 KFO96587.1 - 2.1e-33 116.4 0.0 2.4e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFO96587.1 - 0.043 13.1 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KFO96587.1 - 0.046 14.3 0.1 1.4 9.5 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFO96587.1 - 0.067 12.3 0.0 0.6 9.1 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain MFS_1 PF07690.16 KFO96588.1 - 1.1e-24 87.0 60.5 6.5e-22 77.9 31.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFO96588.1 - 2.7e-24 85.8 26.2 3.8e-24 85.4 26.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Pkinase PF00069.25 KFO96589.1 - 2.3e-52 178.0 0.0 2.6e-52 177.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO96589.1 - 2.2e-19 69.8 0.0 3.4e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFO96589.1 - 0.0081 16.1 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFO96589.1 - 0.041 13.2 0.1 0.065 12.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KFO96589.1 - 0.12 11.3 0.0 0.36 9.8 0.0 1.7 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase SAM_decarbox PF01536.16 KFO96590.1 - 7.8e-112 373.8 2.7 8.8e-112 373.6 2.7 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase TFIIIC_sub6 PF10419.9 KFO96591.1 - 3.5e-17 62.0 0.1 6.2e-17 61.3 0.1 1.4 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Brix PF04427.18 KFO96592.1 - 3.2e-45 154.6 0.1 5.5e-45 153.9 0.1 1.4 1 0 0 1 1 1 1 Brix domain Ion_trans PF00520.31 KFO96593.1 - 5.9e-44 150.1 15.6 6.9e-44 149.9 15.6 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFO96593.1 - 1.4e-11 44.2 2.7 1.4e-11 44.2 2.7 2.8 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.12 KFO96593.1 - 1.9 7.1 8.8 1.1 7.8 2.7 2.1 1 1 1 2 2 2 0 Polycystin cation channel RIC3 PF15361.6 KFO96594.1 - 6.1e-16 59.1 0.3 6.8e-16 59.0 0.3 1.1 1 0 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 CAP PF00188.26 KFO96595.1 - 2.1e-25 90.0 6.2 2.5e-25 89.8 6.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Chorein_N PF12624.7 KFO96596.1 - 3e-17 62.8 0.1 1.9e-15 57.0 0.0 3.5 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 KFO96596.1 - 0.0091 15.8 5.3 0.0091 15.8 2.1 2.6 2 1 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal Csm1_N PF18504.1 KFO96596.1 - 4.1 7.8 6.8 1.4 9.3 1.4 2.7 2 0 0 2 2 2 0 Csm1 N-terminal domain UCH PF00443.29 KFO96597.1 - 1.4e-41 142.7 3.8 1.6e-41 142.5 3.8 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFO96597.1 - 1.5e-24 87.2 11.6 3.8e-24 85.9 11.6 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Tubulin PF00091.25 KFO96598.1 - 5.7e-67 225.7 0.0 8.3e-67 225.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFO96598.1 - 2.1e-51 173.3 0.0 3.5e-51 172.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFO96598.1 - 0.004 16.8 0.0 0.008 15.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 KFO96599.1 - 9e-67 225.1 0.0 1.3e-66 224.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFO96599.1 - 6.7e-51 171.7 0.0 1.1e-50 171.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFO96599.1 - 0.01 15.6 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain Pex26 PF07163.12 KFO96600.1 - 2.5e-101 339.0 0.2 2.9e-101 338.7 0.2 1.0 1 0 0 1 1 1 1 Pex26 protein CH PF00307.31 KFO96601.1 - 4.7e-20 71.8 0.0 1.4e-19 70.2 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFO96601.1 - 9.3e-13 47.8 0.0 2.9e-12 46.3 0.0 1.9 1 0 0 1 1 1 1 CAMSAP CH domain LIM PF00412.22 KFO96601.1 - 8.8e-09 35.5 10.1 1.7e-08 34.6 10.1 1.5 1 0 0 1 1 1 1 LIM domain FAD_binding_3 PF01494.19 KFO96601.1 - 1.2e-05 24.8 0.0 2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KFO96601.1 - 4.5e-05 22.9 0.0 0.0001 21.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFO96601.1 - 0.00019 20.8 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFO96601.1 - 0.00068 18.5 0.0 0.0012 17.6 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KFO96601.1 - 0.0013 17.9 0.0 0.0023 17.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 KFO96601.1 - 0.003 18.0 0.0 0.011 16.2 0.0 1.9 2 0 0 2 2 1 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KFO96601.1 - 0.0041 17.3 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFO96601.1 - 0.0053 17.3 0.0 0.02 15.4 0.0 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFO96601.1 - 0.0066 16.1 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFO96601.1 - 0.027 13.7 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 KFO96601.1 - 0.057 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KFO96601.1 - 0.09 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein BID PF06393.11 KFO96603.1 - 6.5e-49 166.1 3.9 7.2e-49 165.9 3.9 1.0 1 0 0 1 1 1 1 BH3 interacting domain (BID) Bcl-2 PF00452.19 KFO96603.1 - 0.0014 19.3 0.2 0.0019 18.8 0.2 1.2 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family TAFH PF07531.14 KFO96603.1 - 0.0042 17.2 0.3 0.01 15.9 0.1 1.7 1 1 0 1 1 1 1 NHR1 homology to TAF DUF2573 PF10835.8 KFO96603.1 - 0.011 16.0 0.3 0.12 12.7 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2573) HBD PF18534.1 KFO96603.1 - 0.021 14.9 0.4 0.04 14.0 0.2 1.7 1 1 0 1 1 1 0 Helical bundle domain Pox_VLTF3 PF04947.14 KFO96603.1 - 0.026 14.2 1.3 0.034 13.9 0.9 1.4 1 1 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like DUF4413 PF14372.6 KFO96603.1 - 0.049 14.0 0.5 0.056 13.8 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Phage_int_SAM_2 PF12834.7 KFO96603.1 - 0.072 13.8 0.1 0.12 13.0 0.1 1.4 1 0 0 1 1 1 0 Phage integrase, N-terminal DUF3349 PF11829.8 KFO96603.1 - 0.17 12.7 1.8 0.31 11.8 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) ARGLU PF15346.6 KFO96603.1 - 0.42 10.5 6.7 2.5 8.0 2.6 2.0 1 1 1 2 2 2 0 Arginine and glutamate-rich 1 Bcl-2 PF00452.19 KFO96604.1 - 4.9e-12 46.4 0.0 9.2e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family T3SS_needle_E PF08988.10 KFO96604.1 - 0.0056 16.8 0.6 0.0056 16.8 0.6 2.4 2 1 2 4 4 4 1 Type III secretion system, cytoplasmic E component of needle DUF4549 PF15082.6 KFO96604.1 - 0.02 14.7 2.0 0.059 13.1 2.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4549) DUF842 PF05811.13 KFO96604.1 - 0.044 13.5 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Med11 PF10280.9 KFO96604.1 - 0.94 9.9 4.1 0.96 9.9 1.0 2.0 1 1 0 2 2 2 0 Mediator complex protein HSCB_C PF07743.13 KFO96604.1 - 6.9 7.2 10.9 0.2 12.2 1.5 2.5 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain vATP-synt_E PF01991.18 KFO96605.1 - 1.8e-76 256.0 13.4 2.1e-76 255.8 13.4 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Par3_HAL_N_term PF12053.8 KFO96605.1 - 0.0089 16.2 1.5 1.4 9.2 0.1 3.0 2 1 1 3 3 3 1 N-terminal of Par3 and HAL proteins DUF4288 PF14119.6 KFO96605.1 - 0.021 15.2 3.2 0.029 14.8 1.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) DUF3724 PF12521.8 KFO96605.1 - 0.084 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3724) NifW PF03206.14 KFO96605.1 - 0.25 11.9 3.5 0.26 11.8 2.1 1.7 1 1 1 2 2 2 0 Nitrogen fixation protein NifW ATP-synt_B PF00430.18 KFO96605.1 - 0.33 11.0 15.6 0.49 10.5 0.2 2.6 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Bromodomain PF00439.25 KFO96606.1 - 5.3e-21 74.5 0.2 9.7e-21 73.6 0.2 1.4 1 0 0 1 1 1 1 Bromodomain WSD PF15613.6 KFO96606.1 - 0.0044 17.5 0.2 0.0044 17.5 0.2 2.1 2 0 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Ion_trans_2 PF07885.16 KFO96607.1 - 1.1e-20 73.4 19.0 1.1e-15 57.3 8.3 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 KFO96607.1 - 0.74 9.0 17.5 0.2 10.9 7.0 2.2 2 0 0 2 2 2 0 Ion transport protein MutS_V PF00488.21 KFO96608.1 - 4.1e-85 284.6 0.6 7.9e-85 283.6 0.6 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFO96608.1 - 4.6e-36 124.8 1.2 4.6e-36 124.8 1.2 2.0 3 0 0 3 3 3 1 MutS domain III MutS_IV PF05190.18 KFO96608.1 - 8.1e-22 77.4 2.9 2.3e-21 75.9 2.9 1.9 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KFO96608.1 - 1.1e-21 77.6 0.1 4e-21 75.7 0.0 2.0 2 0 0 2 2 2 1 MutS domain II MutS_I PF01624.20 KFO96608.1 - 4.7e-05 23.6 0.0 0.00017 21.8 0.0 2.0 2 0 0 2 2 2 1 MutS domain I AAA_27 PF13514.6 KFO96608.1 - 0.0012 18.4 0.0 0.0053 16.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF2935 PF11155.8 KFO96608.1 - 0.047 14.0 0.3 5.3 7.4 1.0 3.4 2 2 0 2 2 2 0 Domain of unknown function (DUF2935) DUF3800 PF12686.7 KFO96608.1 - 0.12 13.0 1.7 0.69 10.5 1.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3800) Thyroglobulin_1 PF00086.18 KFO96609.1 - 1.3e-11 44.0 2.0 1.3e-11 44.0 2.0 2.4 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat Stevor PF17410.2 KFO96609.1 - 0.00023 20.8 0.0 0.0004 20.0 0.0 1.4 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame RIFIN PF02009.16 KFO96609.1 - 0.022 14.7 0.5 0.023 14.6 0.5 1.3 1 0 0 1 1 1 0 Rifin DAG1 PF05454.11 KFO96609.1 - 0.11 11.9 1.2 0.19 11.1 1.2 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) GCD14 PF08704.10 KFO96610.1 - 3.8e-21 75.9 0.0 1.1e-20 74.4 0.0 1.6 1 1 1 2 2 2 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KFO96610.1 - 2.5e-07 30.7 0.0 3.6e-07 30.2 0.0 1.3 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KFO96610.1 - 1.1e-06 28.5 0.0 2.1e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFO96610.1 - 1.5e-05 25.6 0.0 3.6e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFO96610.1 - 0.00071 20.2 0.0 0.0015 19.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KFO96610.1 - 0.0024 18.8 0.0 0.0036 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFO96610.1 - 0.015 14.6 0.0 0.024 14.0 0.0 1.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CmcI PF04989.12 KFO96610.1 - 0.045 13.4 0.0 0.099 12.3 0.0 1.6 1 1 1 2 2 2 0 Cephalosporin hydroxylase FtsJ PF01728.19 KFO96610.1 - 0.14 12.3 0.0 0.23 11.5 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase DOT1 PF08123.13 KFO96610.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Utp12 PF04003.12 KFO96611.1 - 3.7e-24 85.1 1.6 6.4e-24 84.3 1.6 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 KFO96611.1 - 2.1e-11 44.2 13.0 0.00011 22.9 0.7 4.4 3 1 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO96611.1 - 3.4e-09 36.9 0.2 0.0086 16.4 0.0 3.9 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFO96611.1 - 0.0059 16.0 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 WD40-like domain UTP15_C PF09384.10 KFO96611.1 - 0.012 15.3 0.2 0.026 14.2 0.2 1.6 1 0 0 1 1 1 0 UTP15 C terminal RBD PF02196.15 KFO96611.1 - 0.18 11.9 1.7 19 5.4 0.0 2.7 2 0 0 2 2 2 0 Raf-like Ras-binding domain Saw1 PF11561.8 KFO96611.1 - 0.32 10.5 3.1 0.76 9.3 3.1 1.5 1 0 0 1 1 1 0 Single strand annealing-weakened 1 Retinal PF15449.6 KFO96612.1 - 0 1452.1 84.2 0 1451.9 84.2 1.0 1 0 0 1 1 1 1 Retinal protein Pkinase_Tyr PF07714.17 KFO96613.1 - 9.9e-89 297.0 0.0 1.3e-88 296.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO96613.1 - 2.8e-33 115.4 0.0 4.1e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Gly_rich PF12810.7 KFO96613.1 - 5.6e-17 62.5 25.3 8.4e-17 61.9 24.4 1.6 2 0 0 2 2 2 1 Glycine rich protein MAM PF00629.23 KFO96613.1 - 8.7e-14 51.8 0.0 1.5e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Kinase-like PF14531.6 KFO96613.1 - 0.15 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Ank_5 PF13857.6 KFO96616.1 - 6.5e-07 29.5 0.3 5.6e-06 26.5 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFO96616.1 - 8.3e-07 29.5 0.2 0.00074 20.1 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFO96616.1 - 6.4e-06 26.6 0.3 0.032 14.8 0.4 3.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFO96616.1 - 9.9e-06 25.5 1.7 0.046 14.3 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KFO96616.1 - 0.0026 18.1 0.0 0.0026 18.1 0.0 3.1 4 0 0 4 4 4 1 Ankyrin repeat ALMS_repeat PF18727.1 KFO96616.1 - 0.022 14.6 0.5 0.63 10.0 0.0 2.4 2 0 0 2 2 2 0 Alstrom syndrome repeat Yippee-Mis18 PF03226.14 KFO96617.1 - 3.6e-14 52.8 0.1 4.3e-14 52.6 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SelR PF01641.18 KFO96617.1 - 0.0011 19.1 0.0 0.0014 18.7 0.0 1.2 1 0 0 1 1 1 1 SelR domain RIG-I_C-RD PF11648.8 KFO96617.1 - 0.0015 18.8 0.1 0.0021 18.3 0.1 1.2 1 0 0 1 1 1 1 C-terminal domain of RIG-I HNH_5 PF14279.6 KFO96617.1 - 0.0031 17.3 0.2 0.041 13.7 0.0 2.2 2 0 0 2 2 2 1 HNH endonuclease Endonuclease_7 PF02945.15 KFO96617.1 - 0.0082 16.0 0.7 0.042 13.8 0.4 2.0 1 1 1 2 2 2 1 Recombination endonuclease VII HECT_2 PF09814.9 KFO96617.1 - 0.072 11.9 0.9 0.23 10.3 0.0 1.8 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Sgf11 PF08209.11 KFO96617.1 - 0.19 11.3 2.4 5.9 6.5 0.1 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Lbh PF15317.6 KFO96619.1 - 7.3e-29 100.6 1.4 8.3e-29 100.4 1.4 1.0 1 0 0 1 1 1 1 Cardiac transcription factor regulator, Developmental protein Acyltransferase PF01553.21 KFO96620.1 - 1.8e-23 82.7 0.0 3.8e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KFO96620.1 - 1.6e-19 69.8 0.4 4.5e-19 68.3 0.4 1.8 1 0 0 1 1 1 1 Acyltransferase C-terminus Glycos_transf_2 PF00535.26 KFO96621.1 - 1.9e-22 79.8 0.0 3.1e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFO96621.1 - 1.4e-20 73.8 4.1 2.8e-20 72.9 4.1 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_2 PF10111.9 KFO96621.1 - 0.0001 21.9 0.0 0.00061 19.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KFO96621.1 - 0.00044 19.8 0.0 0.00098 18.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 KFO96621.1 - 0.0033 17.4 0.0 0.0058 16.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF5600 PF18150.1 KFO96622.1 - 5.7e-44 149.1 2.5 5.7e-44 149.1 2.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 KFO96622.1 - 3.2e-19 68.8 0.2 1.8e-18 66.4 0.0 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EHD_N PF16880.5 KFO96622.1 - 2.5e-18 65.7 4.5 5.5e-18 64.6 4.5 1.6 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 KFO96622.1 - 7.6e-13 48.9 0.0 5.6e-12 46.0 0.0 2.2 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KFO96622.1 - 3.3e-09 36.8 0.0 8.6e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 KFO96622.1 - 0.00065 19.1 0.8 0.0025 17.2 0.2 2.4 2 0 0 2 2 1 1 EF hand GTP_EFTU PF00009.27 KFO96622.1 - 0.0062 16.1 0.1 0.089 12.3 0.2 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 KFO96622.1 - 0.0078 16.4 0.0 1.5 9.0 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KFO96622.1 - 0.013 14.9 0.0 0.081 12.2 0.0 2.2 3 0 0 3 3 3 0 AIG1 family Gtr1_RagA PF04670.12 KFO96622.1 - 0.013 14.8 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_28 PF13521.6 KFO96622.1 - 0.034 14.4 0.0 0.16 12.2 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.6 KFO96622.1 - 0.047 14.1 0.1 0.3 11.5 0.0 2.4 2 2 0 2 2 2 0 AAA ATPase domain EF-hand_7 PF13499.6 KFO96622.1 - 0.11 13.0 0.1 0.44 11.0 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair cobW PF02492.19 KFO96622.1 - 0.14 11.8 0.0 20 4.7 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 KFO96622.1 - 0.16 12.0 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE EF-hand_8 PF13833.6 KFO96622.1 - 0.4 10.6 2.0 0.84 9.5 0.3 2.3 2 0 0 2 2 2 0 EF-hand domain pair AAA_23 PF13476.6 KFO96622.1 - 2.8 8.4 5.1 3.9 7.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain Ald_Xan_dh_C2 PF02738.18 KFO96623.1 - 2e-206 686.7 0.0 2.8e-206 686.3 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KFO96623.1 - 6.9e-53 178.9 0.0 1.3e-52 178.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 KFO96623.1 - 7.7e-38 129.2 0.5 1.4e-37 128.4 0.5 1.4 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 KFO96623.1 - 1.4e-31 108.7 0.0 3.2e-31 107.5 0.0 1.7 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 KFO96623.1 - 6.6e-30 102.9 0.1 1.5e-29 101.8 0.1 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 KFO96623.1 - 4.6e-07 29.7 4.7 5.1e-07 29.6 1.1 2.7 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.17 KFO96623.1 - 0.16 12.0 0.0 0.46 10.5 0.0 1.7 1 0 0 1 1 1 0 DUF218 domain rve PF00665.26 KFO96624.1 - 2.7e-26 92.1 0.1 4.6e-26 91.3 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_Zn PF02022.19 KFO96624.1 - 4.1e-14 52.2 0.1 9.5e-14 51.1 0.1 1.7 1 0 0 1 1 1 1 Integrase Zinc binding domain RNase_H PF00075.24 KFO96624.1 - 2.3e-08 34.4 0.0 5.2e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 RNase H UCR_UQCRX_QCR9 PF05365.12 KFO96624.1 - 0.13 12.2 0.3 0.26 11.3 0.3 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like FbpA PF05833.11 KFO96625.1 - 4.1e-35 121.4 17.6 4.1e-35 121.4 17.6 2.4 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 KFO96625.1 - 1.7e-33 115.5 0.4 1.3e-32 112.6 0.0 2.5 2 0 0 2 2 2 1 NFACT protein RNA binding domain NFACT-C PF11923.8 KFO96625.1 - 2.3e-28 98.2 0.1 2.3e-28 98.2 0.1 4.3 5 2 1 6 6 6 1 NFACT protein C-terminal domain DUF5590 PF17881.1 KFO96625.1 - 0.045 13.8 0.2 0.31 11.2 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5590) DUF948 PF06103.11 KFO96625.1 - 6.5 7.1 5.6 2.7 8.3 0.9 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Kelch_4 PF13418.6 KFO96626.1 - 7.8e-25 86.6 22.2 2.4e-09 37.0 0.1 7.7 5 2 2 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KFO96626.1 - 9.3e-25 86.1 15.9 1.5e-05 24.9 0.1 7.6 7 2 0 7 7 7 6 Kelch motif Kelch_1 PF01344.25 KFO96626.1 - 2.3e-22 78.3 16.4 9.9e-06 25.1 0.1 6.6 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 KFO96626.1 - 1.1e-21 76.5 12.7 2.3e-07 30.9 0.2 7.4 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KFO96626.1 - 5e-18 64.7 12.9 5.4e-05 23.3 0.0 6.7 7 0 0 7 7 7 3 Kelch motif Kelch_2 PF07646.15 KFO96626.1 - 5.3e-14 51.6 19.3 0.00037 20.3 0.0 6.9 6 1 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KFO96627.1 - 8.4e-27 92.9 19.8 1.1e-07 31.8 0.4 6.7 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KFO96627.1 - 1.9e-24 85.4 16.6 4.2e-08 33.3 0.1 5.8 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KFO96627.1 - 6.6e-24 83.4 20.3 5.5e-06 26.5 0.3 6.8 3 2 3 6 6 6 4 Kelch motif Kelch_1 PF01344.25 KFO96627.1 - 1.6e-18 66.0 11.5 9.6e-06 25.1 0.1 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KFO96627.1 - 2.7e-17 62.0 18.5 2.8e-06 27.1 0.0 6.1 5 2 1 6 6 6 5 Kelch motif Kelch_5 PF13854.6 KFO96627.1 - 4.4e-17 61.7 6.6 0.00082 19.3 0.1 6.3 6 1 0 6 6 6 4 Kelch motif DNA_pol_E_B PF04042.16 KFO96628.1 - 7.5e-52 175.7 1.2 1.1e-51 175.2 1.2 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.8 KFO96628.1 - 1e-18 67.4 2.2 2e-18 66.4 2.2 1.5 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal MGAT2 PF05060.14 KFO96630.1 - 1.1e-126 422.6 0.5 1.2e-126 422.5 0.5 1.0 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) Gp45_2 PF17470.2 KFO96630.1 - 0.11 12.5 0.2 0.24 11.4 0.2 1.6 1 0 0 1 1 1 0 Phage gene product 45.2 LRR_8 PF13855.6 KFO96631.1 - 2.4e-17 62.4 12.4 1.1e-07 31.5 1.9 3.3 3 0 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFO96631.1 - 7.6e-15 54.8 9.9 4.2e-07 30.2 1.2 3.8 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFO96631.1 - 3.6e-05 23.5 8.3 0.46 10.7 0.2 5.1 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 KFO96631.1 - 0.00029 21.0 18.8 0.51 11.1 0.0 6.5 6 1 0 6 6 6 3 Leucine Rich Repeat Ribosomal_S14 PF00253.21 KFO96632.1 - 2.2e-15 56.2 2.9 2.3e-15 56.0 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.6 KFO96632.1 - 0.056 13.4 0.3 0.07 13.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) 7tm_4 PF13853.6 KFO96633.1 - 1.3e-12 48.1 0.2 1.5e-12 47.9 0.2 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO96633.1 - 7.8e-08 31.9 0.3 1.2e-07 31.3 0.1 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Trypan_PARP PF05887.11 KFO96634.1 - 0.0026 17.7 105.9 0.48 10.4 31.8 4.1 1 1 2 3 3 3 1 Procyclic acidic repetitive protein (PARP) RasGAP PF00616.19 KFO96636.1 - 1.6e-59 201.2 2.9 5.3e-59 199.4 0.0 2.7 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KFO96636.1 - 2.2e-37 128.2 11.7 2.2e-37 128.2 11.7 3.4 3 0 0 3 3 3 1 RasGAP C-terminus CH PF00307.31 KFO96636.1 - 3.8e-19 68.9 0.0 1.7e-18 66.8 0.0 2.3 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.27 KFO96636.1 - 7.7e-19 65.7 20.3 7e-06 25.4 0.6 5.4 5 0 0 5 5 5 4 IQ calmodulin-binding motif WW PF00397.26 KFO96636.1 - 0.0014 18.6 4.6 0.0032 17.5 4.6 1.6 1 0 0 1 1 1 1 WW domain bZIP_1 PF00170.21 KFO96636.1 - 0.022 14.8 0.6 0.022 14.8 0.6 4.1 3 0 0 3 3 3 0 bZIP transcription factor GCP_C_terminal PF04130.13 KFO96637.1 - 2.7e-61 207.7 9.7 4.5e-61 207.0 9.7 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KFO96637.1 - 2.8e-46 158.6 1.5 2.8e-46 158.6 0.2 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal 53-BP1_Tudor PF09038.10 KFO96638.1 - 7.8e-72 238.9 0.3 1.7e-71 237.9 0.3 1.6 1 0 0 1 1 1 1 Tumour suppressor p53-binding protein-1 Tudor BRCT_3 PF18428.1 KFO96638.1 - 8.2e-40 135.0 0.0 1.4e-37 127.8 0.0 3.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain TUDOR_5 PF18359.1 KFO96638.1 - 5.3e-05 22.8 0.3 0.00012 21.7 0.3 1.6 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 BRCT PF00533.26 KFO96638.1 - 0.0009 19.6 0.0 1.7 9.1 0.0 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DUF4537 PF15057.6 KFO96638.1 - 0.0011 19.0 0.0 0.005 16.9 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) BRCT_2 PF16589.5 KFO96638.1 - 0.0017 18.7 0.2 0.012 16.0 0.0 2.6 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KFO96638.1 - 0.0034 17.2 0.0 0.0079 16.1 0.0 1.6 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain Tudor_2 PF18104.1 KFO96638.1 - 2.9 7.6 4.1 0.46 10.2 0.1 1.8 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain Lactamase_B_6 PF16661.5 KFO96639.1 - 0.014 14.9 0.0 0.027 13.9 0.0 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain His_Phos_2 PF00328.22 KFO96640.1 - 1.8e-135 452.2 0.2 2.4e-135 451.8 0.2 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KFO96640.1 - 5.7e-41 138.6 0.3 1.4e-40 137.3 0.3 1.7 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KFO96640.1 - 0.029 14.0 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ATP-gua_Ptrans PF00217.19 KFO96641.1 - 4.6e-82 274.6 0.0 5.7e-82 274.3 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 KFO96641.1 - 9.1e-28 96.5 0.0 1.4e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Thioredoxin PF00085.20 KFO96642.1 - 3.1e-57 190.9 0.1 2.3e-31 107.9 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KFO96642.1 - 2.2e-37 128.8 0.1 4.6e-32 111.4 0.2 2.7 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KFO96642.1 - 8e-07 29.5 0.1 0.0028 18.1 0.1 3.4 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFO96642.1 - 2.8e-05 24.4 0.0 0.0036 17.6 0.0 3.2 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_4 PF13462.6 KFO96642.1 - 0.0006 20.0 0.1 0.07 13.3 0.0 3.0 3 0 0 3 3 3 1 Thioredoxin OST3_OST6 PF04756.13 KFO96642.1 - 0.0016 17.9 0.0 0.26 10.6 0.0 2.7 3 0 0 3 3 3 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KFO96642.1 - 0.0024 18.0 0.0 0.022 14.9 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 KFO96642.1 - 0.048 13.6 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_3 PF13192.6 KFO96642.1 - 0.063 13.3 0.1 3.7 7.7 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin domain Serinc PF03348.15 KFO96643.1 - 2.7e-140 468.1 23.2 3e-140 468.0 23.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) TMEM89 PF15098.6 KFO96643.1 - 0.047 13.9 0.5 0.093 12.9 0.5 1.5 1 0 0 1 1 1 0 TMEM89 protein family RPN6_C_helix PF18503.1 KFO96644.1 - 0.092 12.5 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN6 C-terminal helix domain MFAP1 PF06991.11 KFO96645.1 - 1.1e-78 264.0 30.9 1.1e-78 264.0 30.9 2.1 2 0 0 2 2 2 2 Microfibril-associated/Pre-mRNA processing Glyco_hydro_38N PF01074.22 KFO96646.1 - 8.8e-107 356.8 1.2 1.2e-106 356.3 1.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KFO96646.1 - 3.2e-43 148.3 0.0 4.9e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KFO96646.1 - 3.8e-24 84.6 0.1 8.7e-24 83.5 0.1 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KFO96646.1 - 0.031 14.4 0.0 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain UNC45-central PF11701.8 KFO96647.1 - 7.3e-35 120.2 0.1 7.3e-35 120.2 0.1 4.4 4 1 1 5 5 5 1 Myosin-binding striated muscle assembly central TPR_2 PF07719.17 KFO96647.1 - 1e-05 25.3 0.2 0.00059 19.8 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat HEAT_2 PF13646.6 KFO96647.1 - 2.8e-05 24.4 12.3 0.12 12.7 0.0 6.5 7 1 1 8 8 6 2 HEAT repeats TPR_9 PF13371.6 KFO96647.1 - 0.00024 21.2 0.5 0.00075 19.6 0.5 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFO96647.1 - 0.00061 19.5 0.1 0.11 12.3 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFO96647.1 - 0.0031 17.6 0.1 0.03 14.5 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFO96647.1 - 0.0083 16.7 0.4 0.21 12.3 0.0 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFO96647.1 - 0.027 15.3 1.2 0.11 13.4 0.1 2.7 2 0 0 2 2 1 0 Tetratricopeptide repeat Arm PF00514.23 KFO96647.1 - 0.036 14.1 14.2 4.2 7.6 0.1 7.9 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat TPR_17 PF13431.6 KFO96647.1 - 0.058 13.8 0.0 0.49 10.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_N PF14852.6 KFO96647.1 - 0.064 12.9 0.0 39 4.0 0.0 3.8 4 0 0 4 4 4 0 Fis1 N-terminal tetratricopeptide repeat V-ATPase_H_N PF03224.14 KFO96647.1 - 0.11 11.8 4.5 0.93 8.7 0.2 3.9 4 1 0 5 5 5 0 V-ATPase subunit H RCC1 PF00415.18 KFO96648.1 - 3e-25 88.6 0.4 8.9e-13 48.6 0.3 2.8 2 1 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFO96648.1 - 1.2e-13 50.5 5.9 1.3e-09 37.6 1.1 2.3 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat MAP65_ASE1 PF03999.12 KFO96649.1 - 1.9e-151 505.8 24.1 2.2e-151 505.5 24.1 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) CHASE8 PF17152.4 KFO96649.1 - 0.097 12.9 0.2 0.36 11.1 0.2 2.0 1 0 0 1 1 1 0 Periplasmic sensor domain Mvb12 PF09452.10 KFO96649.1 - 0.11 12.9 0.4 0.11 12.9 0.4 2.8 3 1 0 3 3 3 0 ESCRT-I subunit Mvb12 Sec1 PF00995.23 KFO96650.1 - 3.1e-82 277.7 0.0 3.8e-82 277.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Calreticulin PF00262.18 KFO96650.1 - 0.059 12.2 0.2 2.2 7.1 0.0 2.1 2 0 0 2 2 2 0 Calreticulin family TTL PF03133.15 KFO96651.1 - 6.2e-90 301.3 0.1 1.2e-89 300.4 0.1 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KFO96651.1 - 2.5e-09 36.8 0.1 4.3e-05 22.9 0.0 3.4 2 2 1 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KFO96651.1 - 3.9e-05 23.0 0.0 0.016 14.5 0.0 2.6 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 KFO96651.1 - 0.0048 17.0 0.0 0.019 15.0 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 KFO96651.1 - 0.012 15.2 0.0 3.4 7.2 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 KFO96651.1 - 0.04 13.4 0.0 0.097 12.2 0.0 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus FAM195 PF14799.6 KFO96651.1 - 0.077 13.3 1.0 0.21 12.0 1.0 1.7 1 0 0 1 1 1 0 FAM195 family EF-hand_7 PF13499.6 KFO96652.1 - 4.7e-15 55.8 5.1 5.2e-13 49.2 3.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFO96652.1 - 2.3e-11 42.7 5.8 2.7e-05 23.7 0.6 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 KFO96652.1 - 3.1e-11 42.0 6.1 3.2e-05 23.2 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KFO96652.1 - 1.3e-07 31.3 7.6 0.0021 17.9 3.3 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFO96652.1 - 9.9e-07 28.0 5.6 0.009 15.5 0.6 2.9 2 1 1 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 KFO96652.1 - 7.3e-05 23.1 0.9 0.00074 19.8 0.9 2.2 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KFO96652.1 - 0.00093 19.3 0.1 0.0016 18.6 0.1 1.4 1 0 0 1 1 1 1 Dockerin type I domain EF-hand_4 PF12763.7 KFO96652.1 - 0.03 14.3 6.2 0.31 11.0 0.2 2.8 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFO96652.1 - 0.047 14.0 1.5 0.15 12.4 0.1 2.3 2 1 0 2 2 2 0 EF-hand domain NuiA PF07924.11 KFO96652.1 - 0.13 12.6 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein S_100 PF01023.19 KFO96652.1 - 0.33 10.7 4.7 5.7 6.7 0.0 3.6 4 0 0 4 4 4 0 S-100/ICaBP type calcium binding domain Gal4_dimer PF03902.13 KFO96652.1 - 0.91 9.7 7.5 0.86 9.8 0.6 3.1 1 1 1 2 2 2 0 Gal4-like dimerisation domain PX PF00787.24 KFO96653.1 - 1.6e-19 70.0 0.1 3.5e-19 68.9 0.1 1.6 1 0 0 1 1 1 1 PX domain RA PF00788.23 KFO96653.1 - 6.4e-12 46.0 0.1 2.4e-11 44.1 0.0 2.1 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain SNX17_FERM_C PF18116.1 KFO96653.1 - 0.00018 21.6 0.3 0.00065 19.7 0.3 2.1 1 0 0 1 1 1 1 Sorting Nexin 17 FERM C-terminal domain USP7_C2 PF14533.6 KFO96653.1 - 0.00062 19.5 0.1 0.0014 18.4 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-specific protease C-terminal PDZ_6 PF17820.1 KFO96653.1 - 0.023 14.6 0.1 0.05 13.5 0.1 1.6 1 0 0 1 1 1 0 PDZ domain KASH_CCD PF14662.6 KFO96654.1 - 5.7e-05 23.0 16.3 7.5e-05 22.6 16.3 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Cast PF10174.9 KFO96654.1 - 8.4e-05 21.0 13.3 0.0001 20.8 13.3 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Prominin PF05478.11 KFO96654.1 - 0.0021 16.1 1.7 0.0021 16.1 1.7 1.0 1 0 0 1 1 1 1 Prominin bZIP_1 PF00170.21 KFO96654.1 - 0.0022 18.1 17.2 0.023 14.8 0.4 3.4 3 1 0 3 3 3 2 bZIP transcription factor Fmp27_WPPW PF10359.9 KFO96654.1 - 0.004 16.1 6.8 0.0055 15.6 6.8 1.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF4200 PF13863.6 KFO96654.1 - 0.01 16.2 18.0 0.061 13.7 18.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.9 KFO96654.1 - 0.028 14.4 20.5 0.8 9.7 20.4 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.7 KFO96654.1 - 0.032 14.4 18.1 0.085 13.0 18.1 1.7 1 1 0 1 1 1 0 Tropomyosin like Jnk-SapK_ap_N PF09744.9 KFO96654.1 - 0.037 14.3 17.2 0.87 9.8 2.3 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF4988 PF16378.5 KFO96654.1 - 0.042 13.5 3.4 0.35 10.5 0.8 2.3 1 1 1 2 2 2 0 Domain of unknown function SlyX PF04102.12 KFO96654.1 - 0.044 14.4 6.6 0.044 14.4 6.6 3.2 1 1 2 3 3 3 0 SlyX Exonuc_VII_L PF02601.15 KFO96654.1 - 0.046 13.3 6.6 0.052 13.1 6.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Aminopep PF10023.9 KFO96654.1 - 0.057 12.8 2.2 0.076 12.4 2.2 1.1 1 0 0 1 1 1 0 Putative aminopeptidase Spc7 PF08317.11 KFO96654.1 - 0.073 11.9 14.2 0.1 11.4 14.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein COG5 PF10392.9 KFO96654.1 - 0.091 12.9 5.0 0.12 12.6 5.0 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Bacillus_HBL PF05791.11 KFO96654.1 - 0.11 12.4 5.2 0.26 11.1 4.3 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) SpoIISA_toxin PF14171.6 KFO96654.1 - 0.11 12.2 1.4 0.15 11.8 1.4 1.2 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system DUF4407 PF14362.6 KFO96654.1 - 0.12 11.7 4.4 0.14 11.5 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CALCOCO1 PF07888.11 KFO96654.1 - 0.14 10.9 16.9 0.21 10.4 16.9 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like HOOK PF05622.12 KFO96654.1 - 0.16 10.1 16.0 0.18 9.9 16.0 1.0 1 0 0 1 1 1 0 HOOK protein E2F_CC-MB PF16421.5 KFO96654.1 - 0.16 12.3 7.0 1.1 9.7 7.0 2.3 1 1 0 1 1 1 0 E2F transcription factor CC-MB domain DHR10 PF18595.1 KFO96654.1 - 0.19 11.8 20.5 0.041 13.9 13.4 2.2 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain ADIP PF11559.8 KFO96654.1 - 0.2 11.7 15.9 0.55 10.3 11.2 2.6 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding CLZ PF16526.5 KFO96654.1 - 0.23 11.8 18.1 0.25 11.7 6.9 3.2 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 KFO96654.1 - 0.26 11.3 10.1 0.34 10.9 8.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) MPS2 PF17060.5 KFO96654.1 - 0.36 10.0 6.9 0.39 9.9 6.9 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 CREPT PF16566.5 KFO96654.1 - 0.37 11.0 11.9 0.57 10.3 11.9 1.4 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF2937 PF11157.8 KFO96654.1 - 0.42 10.3 4.7 0.67 9.6 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) UPF0242 PF06785.11 KFO96654.1 - 0.54 10.3 15.2 0.8 9.8 15.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Tfb5 PF06331.12 KFO96654.1 - 0.55 10.3 5.0 0.85 9.7 4.3 1.7 1 1 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 FAM76 PF16046.5 KFO96654.1 - 0.55 9.5 11.3 1.3 8.3 11.3 1.7 1 1 0 1 1 1 0 FAM76 protein DUF724 PF05266.14 KFO96654.1 - 0.57 10.0 12.5 0.76 9.6 12.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Atg14 PF10186.9 KFO96654.1 - 0.61 9.1 14.6 1 8.4 14.6 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4795 PF16043.5 KFO96654.1 - 0.72 9.4 15.9 3.1 7.3 15.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF1465 PF07323.12 KFO96654.1 - 0.76 9.6 8.0 6.4 6.6 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) DUF16 PF01519.16 KFO96654.1 - 0.79 10.2 12.1 0.38 11.2 6.6 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 AKNA PF12443.8 KFO96654.1 - 1.1 10.0 9.0 0.82 10.4 5.6 2.3 1 1 1 2 2 2 0 AT-hook-containing transcription factor DUF3740 PF12548.8 KFO96654.1 - 1.1 9.6 8.1 0.51 10.8 2.4 2.3 1 1 0 2 2 2 0 Sulfatase protein GrpE PF01025.19 KFO96654.1 - 1.2 8.7 13.7 14 5.3 10.2 2.7 1 1 1 2 2 2 0 GrpE bZIP_2 PF07716.15 KFO96654.1 - 1.3 9.2 18.5 0.25 11.4 0.7 3.6 3 2 0 3 3 3 0 Basic region leucine zipper Fib_alpha PF08702.10 KFO96654.1 - 1.3 9.2 11.1 1.3 9.2 8.6 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF848 PF05852.11 KFO96654.1 - 1.3 9.1 10.7 0.51 10.4 2.4 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) BLOC1_2 PF10046.9 KFO96654.1 - 1.4 9.2 11.4 0.46 10.8 3.0 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.11 KFO96654.1 - 1.4 9.1 17.6 0.79 9.9 12.0 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.19 KFO96654.1 - 1.5 6.7 7.9 1.6 6.6 7.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 KFO96654.1 - 1.5 8.6 17.3 2.6 7.9 4.9 3.1 1 1 2 3 3 3 0 Septum formation initiator FapA PF03961.13 KFO96654.1 - 1.7 7.2 12.2 1.1 7.8 10.1 1.5 1 1 1 2 2 2 0 Flagellar Assembly Protein A ZapB PF06005.12 KFO96654.1 - 2 8.9 22.0 58 4.2 13.9 3.1 1 1 1 2 2 2 0 Cell division protein ZapB Sec2p PF06428.11 KFO96654.1 - 2 8.4 15.1 0.29 11.1 3.4 3.0 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p TSC22 PF01166.18 KFO96654.1 - 2.2 8.7 9.6 6.1 7.2 0.7 3.3 1 1 2 3 3 3 0 TSC-22/dip/bun family TMPIT PF07851.13 KFO96654.1 - 2.2 7.5 6.6 2.5 7.3 6.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein CCDC-167 PF15188.6 KFO96654.1 - 2.3 8.6 15.5 0.58 10.5 2.6 3.0 1 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 COG2 PF06148.11 KFO96654.1 - 3.8 7.6 9.9 5.9 7.0 7.6 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Prefoldin_2 PF01920.20 KFO96654.1 - 3.9 7.5 18.1 1.5 8.8 5.0 3.0 1 1 2 3 3 3 0 Prefoldin subunit Lzipper-MIP1 PF14389.6 KFO96654.1 - 4.7 7.6 18.4 0.54 10.6 10.6 2.6 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Cnn_1N PF07989.11 KFO96654.1 - 4.9 7.4 15.0 2.7 8.2 9.4 2.6 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF737 PF05300.11 KFO96654.1 - 5.7 7.2 13.8 7.9 6.8 13.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Csm1_N PF18504.1 KFO96654.1 - 5.7 7.3 13.9 8.6 6.8 4.1 3.2 1 1 1 3 3 3 0 Csm1 N-terminal domain Seryl_tRNA_N PF02403.22 KFO96654.1 - 5.8 7.2 14.4 3.4 8.0 4.2 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF641 PF04859.12 KFO96654.1 - 6.2 7.2 12.8 19 5.6 8.9 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) YabA PF06156.13 KFO96654.1 - 6.8 7.4 14.1 2.9 8.6 3.9 2.9 1 1 2 3 3 3 0 Initiation control protein YabA TTRAP PF14203.6 KFO96654.1 - 7.1 6.7 7.7 1.7 8.7 0.3 2.9 2 1 0 3 3 3 0 Putative tranposon-transfer assisting protein Proteasome PF00227.26 KFO96655.1 - 5.9e-28 97.6 0.0 6.9e-28 97.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Glycos_trans_3N PF02885.17 KFO96655.1 - 0.15 11.9 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain zf-C2H2_4 PF13894.6 KFO96656.1 - 3.9e-12 45.9 52.0 0.023 15.5 0.6 7.6 7 0 0 7 7 7 5 C2H2-type zinc finger zf-Di19 PF05605.12 KFO96656.1 - 2.2e-05 24.7 40.6 0.022 15.0 0.4 5.3 4 1 1 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KFO96656.1 - 0.001 19.4 56.1 0.2 12.2 0.2 7.6 7 1 0 7 7 6 5 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFO96656.1 - 0.004 17.4 31.2 0.089 13.1 0.9 6.1 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KFO96656.1 - 0.0075 16.7 5.3 0.055 13.9 0.3 6.7 9 0 0 9 9 7 4 Zinc-finger double domain PyrI_C PF02748.15 KFO96656.1 - 0.14 12.1 0.1 0.14 12.1 0.1 4.6 4 1 1 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain FYVE PF01363.21 KFO96656.1 - 0.21 11.8 0.1 0.21 11.8 0.1 4.8 3 1 1 4 4 3 0 FYVE zinc finger FOXP-CC PF16159.5 KFO96656.1 - 0.46 11.1 19.1 2.6 8.7 0.1 4.6 2 1 2 4 4 4 0 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 KFO96656.1 - 0.54 10.1 0.0 0.54 10.1 0.0 4.4 5 0 0 5 5 5 0 zinc-finger C2H2-type Rubredoxin PF00301.20 KFO96656.1 - 0.6 10.2 0.0 0.6 10.2 0.0 6.0 7 0 0 7 7 6 0 Rubredoxin zinc_ribbon_15 PF17032.5 KFO96656.1 - 1.9 9.3 22.7 0.35 11.7 0.4 4.5 3 2 2 5 5 5 0 zinc-ribbon family Zn-C2H2_12 PF18112.1 KFO96656.1 - 2.7 8.5 16.6 2.4 8.7 0.7 4.5 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain zinc_ribbon_4 PF13717.6 KFO96656.1 - 5 7.1 20.3 1.1 9.2 0.1 5.4 6 0 0 6 6 5 0 zinc-ribbon domain zf-C2H2_2 PF12756.7 KFO96656.1 - 5.7 7.3 38.3 4 7.8 1.2 5.9 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_5 PF13719.6 KFO96656.1 - 8.1 6.3 10.4 4.5 7.1 0.2 4.1 4 0 0 4 4 4 0 zinc-ribbon domain SBP56 PF05694.11 KFO96657.1 - 1.9e-212 706.1 0.0 2.1e-212 705.9 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 KFO96657.1 - 0.00038 19.8 0.0 0.0028 17.0 0.0 2.2 3 0 0 3 3 3 1 Lactonase, 7-bladed beta-propeller SBP56 PF05694.11 KFO96658.1 - 7.1e-111 371.2 0.0 3.6e-72 243.6 0.0 2.0 2 0 0 2 2 2 2 56kDa selenium binding protein (SBP56) RFX_DNA_binding PF02257.15 KFO96659.1 - 1.8e-28 98.9 0.1 5.3e-27 94.3 0.0 2.1 2 0 0 2 2 2 1 RFX DNA-binding domain RFX5_N PF18326.1 KFO96659.1 - 1.4e-14 53.6 1.7 2e-14 53.1 1.7 1.3 1 0 0 1 1 1 1 RFX5 N-terminal domain Pox_D5 PF03288.16 KFO96659.1 - 0.0022 18.4 0.0 0.0034 17.8 0.0 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like PI3_PI4_kinase PF00454.27 KFO96660.1 - 7.2e-34 117.7 0.5 3.1e-22 79.6 0.2 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 KFO96660.1 - 0.023 14.0 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) VWA_2 PF13519.6 KFO96661.1 - 2.5e-06 28.1 0.1 3.5e-05 24.4 0.0 2.7 3 0 0 3 3 3 1 von Willebrand factor type A domain UIM PF02809.20 KFO96661.1 - 0.0001 22.0 0.4 0.0001 22.0 0.4 2.4 3 0 0 3 3 3 1 Ubiquitin interaction motif RAP80_UIM PF18282.1 KFO96661.1 - 0.0086 15.8 3.0 0.022 14.5 3.0 1.7 1 0 0 1 1 1 1 RAP80 N-terminal ubiquitin interaction motif PIP5K PF01504.18 KFO96662.1 - 1.8e-89 299.6 0.0 2.2e-89 299.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase YL1 PF05764.13 KFO96663.1 - 1.9e-28 100.3 23.4 1.6e-27 97.2 23.4 2.0 1 1 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.11 KFO96663.1 - 1.1e-12 47.4 0.5 2.5e-12 46.3 0.5 1.6 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Tropomodulin PF03250.14 KFO96664.1 - 2.3e-36 124.9 1.0 3.3e-36 124.5 0.2 1.6 2 0 0 2 2 2 1 Tropomodulin LRR_6 PF13516.6 KFO96664.1 - 0.5 10.5 0.1 0.5 10.5 0.1 3.6 4 0 0 4 4 4 0 Leucine Rich repeat Lipase3_N PF03893.16 KFO96665.1 - 0.44 10.6 5.2 53 3.9 0.2 3.5 3 0 0 3 3 3 0 Lipase 3 N-terminal region Ank_2 PF12796.7 KFO96666.1 - 1.8e-29 102.1 0.7 3.7e-15 56.3 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFO96666.1 - 2e-21 75.4 3.9 5.3e-08 33.0 0.2 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KFO96666.1 - 7.1e-21 72.1 0.2 1.2e-05 25.3 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KFO96666.1 - 4e-19 68.7 1.2 4.5e-10 39.8 0.2 2.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFO96666.1 - 9.6e-18 64.0 2.2 8e-06 26.0 0.1 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) PBD PF00786.28 KFO96667.1 - 0.00017 21.9 0.1 0.00031 21.0 0.1 1.4 1 0 0 1 1 1 1 P21-Rho-binding domain DUF5604 PF18300.1 KFO96668.1 - 2.5e-18 65.8 1.3 3.7e-18 65.2 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5604) DUF2203 PF09969.9 KFO96668.1 - 0.54 11.0 4.9 3.7 8.3 2.5 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) PAS_3 PF08447.12 KFO96669.1 - 1.6e-23 82.8 0.0 1.3e-17 63.8 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KFO96669.1 - 4.9e-22 78.2 0.3 1.1e-19 70.6 0.3 2.6 2 1 0 2 2 2 1 PAS domain PAS PF00989.25 KFO96669.1 - 1e-20 73.8 0.1 6.6e-13 48.7 0.0 2.8 3 0 0 3 3 3 2 PAS fold HLH PF00010.26 KFO96669.1 - 4.5e-12 45.7 1.3 1.2e-11 44.3 1.1 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 KFO96669.1 - 2.8e-09 37.2 0.0 2.9e-06 27.5 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KFO96669.1 - 0.0043 17.3 0.0 1 9.7 0.0 2.6 2 0 0 2 2 2 1 PAS fold Peptidase_C1 PF00112.23 KFO96670.1 - 6.3e-24 85.3 2.3 6.7e-24 85.2 2.3 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KFO96670.1 - 2.8e-05 23.1 0.5 3.1e-05 22.9 0.5 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KFO96671.1 - 2.9e-83 279.3 1.4 3.3e-83 279.1 1.4 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KFO96671.1 - 2.5e-05 23.2 1.9 0.03 13.1 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Inhibitor_I29 PF08246.12 KFO96671.1 - 0.00066 20.1 0.0 0.0012 19.3 0.0 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C2 PF00648.21 KFO96671.1 - 0.1 11.6 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Calpain family cysteine protease PINIT PF14324.6 KFO96672.1 - 2e-37 128.8 0.1 3.4e-37 128.0 0.1 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KFO96672.1 - 3.5e-21 74.7 5.1 8e-21 73.5 5.1 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KFO96672.1 - 2e-05 24.3 1.1 4.7e-05 23.1 1.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 KFO96672.1 - 0.027 14.2 0.1 0.064 13.0 0.1 1.6 1 0 0 1 1 1 0 SAP domain MRNIP PF15749.5 KFO96672.1 - 0.1 13.4 0.1 0.22 12.2 0.1 1.5 1 0 0 1 1 1 0 MRN-interacting protein Prok-RING_4 PF14447.6 KFO96672.1 - 2.7 7.9 8.3 0.11 12.3 1.9 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 PHD PF00628.29 KFO96672.1 - 6 6.8 7.8 0.43 10.5 2.2 2.0 2 0 0 2 2 2 0 PHD-finger RNA_pol_Rpc82 PF05645.13 KFO96673.1 - 1e-37 130.3 0.0 7.3e-37 127.5 0.0 2.4 2 1 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 KFO96673.1 - 1.6e-08 34.6 4.6 0.0018 18.3 0.5 4.2 4 0 0 4 4 4 3 RNA polymerase III subunit RPC82 helix-turn-helix domain PilJ PF13675.6 KFO96673.1 - 0.19 11.8 1.9 0.41 10.7 1.9 1.5 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term zf-RING_2 PF13639.6 KFO96674.1 - 1.2e-12 48.0 7.5 1.2e-12 48.0 7.5 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFO96674.1 - 8.3e-09 35.2 7.7 8.3e-09 35.2 7.7 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFO96674.1 - 1.1e-08 34.6 3.6 6.7e-08 32.1 2.2 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KFO96674.1 - 1.7e-07 31.1 2.2 1.7e-07 31.1 2.2 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFO96674.1 - 1.1e-06 28.4 6.8 1.1e-06 28.4 6.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFO96674.1 - 1.5e-06 28.4 8.8 1.5e-06 28.4 8.8 2.0 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFO96674.1 - 4.7e-06 26.4 5.0 4.7e-06 26.4 5.0 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KFO96674.1 - 1.5e-05 25.0 3.9 0.00029 20.8 3.3 2.7 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KFO96674.1 - 1.5e-05 24.8 3.2 1.5e-05 24.8 3.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFO96674.1 - 0.001 18.9 10.8 0.0029 17.4 8.1 2.7 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zinc_ribbon_9 PF14369.6 KFO96674.1 - 0.0097 16.2 0.8 0.0097 16.2 0.8 3.1 3 0 0 3 3 3 1 zinc-ribbon zf-RING_6 PF14835.6 KFO96674.1 - 0.022 14.6 1.9 0.056 13.3 1.9 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 KFO96674.1 - 0.026 14.3 3.3 0.052 13.4 3.3 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 KFO96674.1 - 0.026 14.1 3.8 0.065 12.9 3.8 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Vps39_2 PF10367.9 KFO96674.1 - 0.035 14.5 1.5 2.9 8.4 0.6 2.5 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-HC5HC2H_2 PF13832.6 KFO96674.1 - 0.16 12.2 0.3 0.16 12.2 0.3 1.6 1 1 1 2 2 2 0 PHD-zinc-finger like domain DUF983 PF06170.12 KFO96674.1 - 0.16 12.4 3.2 4.9 7.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF983) zf-HC5HC2H PF13771.6 KFO96674.1 - 0.17 12.2 0.3 0.17 12.2 0.3 1.7 1 1 1 2 2 2 0 PHD-like zinc-binding domain Zn-C2H2_12 PF18112.1 KFO96674.1 - 0.18 12.3 5.2 4.8 7.7 0.1 3.5 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-H2C2_2 PF13465.6 KFO96674.1 - 0.22 12.0 5.0 38 4.9 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-RING_4 PF14570.6 KFO96674.1 - 0.52 10.1 8.2 4.8 7.1 0.0 3.0 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain HypA PF01155.19 KFO96674.1 - 0.77 9.8 2.8 1.4 9.0 1.0 2.0 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rad50_zn_hook PF04423.14 KFO96674.1 - 1 9.3 10.2 0.65 9.9 0.3 3.4 4 0 0 4 4 3 0 Rad50 zinc hook motif zf-Di19 PF05605.12 KFO96674.1 - 1.8 8.9 11.5 39 4.7 7.2 3.3 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Prok-RING_1 PF14446.6 KFO96674.1 - 2.6 8.0 7.4 6.9 6.7 0.1 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Opy2 PF09463.10 KFO96674.1 - 2.8 8.4 8.3 24 5.3 0.3 3.3 3 0 0 3 3 3 0 Opy2 protein TF_Zn_Ribbon PF08271.12 KFO96674.1 - 2.9 7.5 6.7 14 5.3 0.1 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.7 KFO96674.1 - 3.2 7.8 5.9 31 4.7 0.6 3.1 3 0 0 3 3 3 0 Transposase zinc-ribbon domain zf-C3HC4_4 PF15227.6 KFO96674.1 - 5.6 7.2 10.5 6.9 6.9 7.2 2.7 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING PHD PF00628.29 KFO96674.1 - 8.9 6.3 10.5 8.3 6.4 5.2 2.7 2 1 1 3 3 3 0 PHD-finger LIX1 PF14954.6 KFO96675.1 - 2.9e-131 436.2 0.8 3.3e-131 436.1 0.8 1.0 1 0 0 1 1 1 1 Limb expression 1 Dicer_dimer PF03368.14 KFO96675.1 - 0.061 13.5 0.0 0.15 12.2 0.0 1.7 2 0 0 2 2 2 0 Dicer dimerisation domain RRM_1 PF00076.22 KFO96676.1 - 9.1e-19 67.1 0.0 1.6e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFO96676.1 - 9.6e-07 28.8 0.0 4.3e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 RNA binding motif RRM_5 PF13893.6 KFO96676.1 - 7.1e-05 22.4 0.0 0.0001 21.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arrestin_N PF00339.29 KFO96677.1 - 1.4e-20 73.8 0.0 2.7e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KFO96677.1 - 5.8e-16 59.2 0.0 1.8e-14 54.4 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain RGM_N PF06535.12 KFO96678.1 - 2.7e-68 229.3 0.6 4e-68 228.8 0.6 1.3 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) N-terminus RGM_C PF06534.13 KFO96678.1 - 2.8e-64 215.8 0.2 8.6e-64 214.2 0.2 1.8 1 1 0 1 1 1 1 Repulsive guidance molecule (RGM) C-terminus VWD PF00094.25 KFO96678.1 - 0.041 14.2 0.0 0.065 13.5 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type D domain MFS_1 PF07690.16 KFO96679.1 - 5.5e-28 97.9 46.4 8.1e-18 64.5 30.8 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFO96679.1 - 7.1e-21 74.6 30.0 1.1e-16 60.8 9.2 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter Pentapeptide_4 PF13599.6 KFO96679.1 - 1.7e-05 24.9 8.5 2.6e-05 24.3 7.6 1.7 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) MFS_4 PF06779.14 KFO96679.1 - 0.00057 19.3 10.1 0.00057 19.3 10.1 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 KFO96679.1 - 0.004 15.6 8.5 0.018 13.5 3.9 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector Pentapeptide_3 PF13576.6 KFO96679.1 - 0.047 13.8 6.3 0.12 12.5 6.3 1.8 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 KFO96679.1 - 0.048 13.3 0.3 0.11 12.2 0.3 1.6 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) RRM_1 PF00076.22 KFO96680.1 - 2.9e-40 135.9 0.0 3.4e-20 71.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFO96680.1 - 9.8e-07 28.8 0.0 0.00068 19.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 KFO96680.1 - 0.00022 20.8 0.0 0.28 10.8 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 KFO96680.1 - 0.0035 17.0 0.1 0.16 11.7 0.0 2.3 2 0 0 2 2 2 1 Ribonuclease B OB domain Limkain-b1 PF11608.8 KFO96680.1 - 0.016 15.3 0.0 1.6 8.9 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 OTU PF02338.19 KFO96681.1 - 3.1e-24 85.9 0.0 6.4e-24 84.9 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease UBA_4 PF14555.6 KFO96681.1 - 0.00013 21.7 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 KFO96681.1 - 0.00053 19.6 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 TAP C-terminal domain CCDC106 PF15794.5 KFO96681.1 - 0.12 12.1 3.3 0.3 10.7 3.3 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 RPA43_OB PF17875.1 KFO96681.1 - 0.72 10.5 4.6 2.7 8.6 0.2 2.5 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Sec1 PF00995.23 KFO96682.1 - 1.3e-111 374.7 0.1 1.7e-111 374.3 0.1 1.1 1 0 0 1 1 1 1 Sec1 family PH PF00169.29 KFO96683.1 - 9.9e-13 48.5 0.7 2.2e-12 47.4 0.7 1.6 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KFO96683.1 - 0.0011 19.4 0.6 0.02 15.3 0.6 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFO96683.1 - 0.004 17.5 0.6 0.015 15.7 0.6 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3055 PF11256.8 KFO96683.1 - 0.26 11.6 2.2 1.6 9.1 0.2 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3055) DUF3439 PF11921.8 KFO96683.1 - 0.34 10.9 2.6 0.85 9.6 2.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) LRR_4 PF12799.7 KFO96684.1 - 7.8e-16 57.9 13.4 4e-09 36.6 4.4 3.4 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFO96684.1 - 2.1e-15 56.6 0.7 2.6e-15 56.3 0.7 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KFO96684.1 - 1.6e-08 34.2 3.8 1.6e-08 34.2 3.8 2.9 2 1 1 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 KFO96684.1 - 9e-08 31.6 7.0 0.0012 18.8 0.2 4.0 3 0 0 3 3 3 3 Leucine Rich repeat LRR_1 PF00560.33 KFO96684.1 - 2.2e-05 24.4 9.3 1.9 9.4 0.1 4.5 4 0 0 4 4 4 3 Leucine Rich Repeat CobT PF06213.12 KFO96684.1 - 0.61 9.4 13.8 0.75 9.1 13.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ribosomal_S21 PF01165.20 KFO96685.1 - 4e-11 42.5 3.7 5.2e-11 42.1 3.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S21 APG17 PF04108.12 KFO96685.1 - 0.45 9.6 0.9 0.53 9.3 0.9 1.0 1 0 0 1 1 1 0 Autophagy protein Apg17 PRP3 PF08572.10 KFO96686.1 - 2e-80 269.7 7.1 2e-80 269.7 7.1 3.2 3 1 1 4 4 4 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KFO96686.1 - 1.6e-48 164.5 2.1 1.6e-48 164.5 2.1 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1115) PWI PF01480.17 KFO96686.1 - 1.9e-13 50.5 0.0 5.4e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 PWI domain TPX2 PF06886.11 KFO96686.1 - 0.058 13.6 0.4 0.058 13.6 0.4 5.9 7 0 0 7 7 7 0 Targeting protein for Xklp2 (TPX2) UPF0767 PF15990.5 KFO96686.1 - 9.4 6.5 6.3 7.7 6.7 0.8 3.0 2 0 0 2 2 2 0 UPF0767 family CTD_bind PF04818.13 KFO96687.1 - 1.6e-17 64.1 2.2 1.7e-17 64.0 0.3 2.2 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CREPT PF16566.5 KFO96687.1 - 1.1e-07 32.1 0.6 1.1e-07 32.1 0.6 2.0 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour Acetyltransf_11 PF13720.6 KFO96687.1 - 0.08 13.4 0.1 11 6.5 0.0 2.6 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Lzipper-MIP1 PF14389.6 KFO96687.1 - 0.46 10.8 2.0 60 4.0 0.0 3.6 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 FadA PF09403.10 KFO96687.1 - 1.1 9.8 5.5 10 6.7 0.3 3.3 2 1 1 3 3 3 0 Adhesion protein FadA tRNA-synt_2b PF00587.25 KFO96688.1 - 3.7e-32 111.7 0.0 5.7e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_SAD PF07973.14 KFO96688.1 - 0.085 13.0 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 Threonyl and Alanyl tRNA synthetase second additional domain Lambda_Kil PF06301.11 KFO96688.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage lambda Kil protein Ribosomal_S27e PF01667.17 KFO96689.1 - 9.7e-28 95.7 3.7 1.2e-27 95.4 3.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 DUF3795 PF12675.7 KFO96689.1 - 0.022 15.1 2.0 0.094 13.1 2.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) E7 PF00527.18 KFO96689.1 - 0.073 13.3 0.2 0.073 13.3 0.2 1.3 1 1 0 1 1 1 0 E7 protein, Early protein ubiquitin PF00240.23 KFO96690.1 - 8.5e-13 47.9 0.2 1.4e-12 47.1 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin family STI1 PF17830.1 KFO96690.1 - 2.4e-08 33.8 59.7 0.00026 20.9 11.7 7.1 5 2 1 6 6 6 4 STI1 domain UBA PF00627.31 KFO96690.1 - 1.1e-06 28.4 0.9 1.1e-06 28.4 0.9 2.4 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.8 KFO96690.1 - 0.0021 17.8 0.1 0.004 17.0 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Arm_2 PF04826.13 KFO96690.1 - 0.0072 15.8 0.3 0.0072 15.8 0.3 2.9 3 0 0 3 3 3 1 Armadillo-like Ubiquitin_5 PF18037.1 KFO96690.1 - 0.0081 16.5 0.2 0.022 15.1 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain HOIP-UBA PF16678.5 KFO96690.1 - 0.046 13.7 0.0 0.09 12.8 0.0 1.5 1 0 0 1 1 1 0 HOIP UBA domain pair CUE PF02845.16 KFO96690.1 - 0.054 13.2 0.0 0.25 11.1 0.0 2.3 1 0 0 1 1 1 0 CUE domain Rad60-SLD_2 PF13881.6 KFO96690.1 - 0.13 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ComX PF05952.12 KFO96690.1 - 0.61 10.1 8.4 35 4.4 0.2 5.1 4 1 1 5 5 5 0 Bacillus competence pheromone ComX RAP1 PF07218.11 KFO96690.1 - 4.3 5.5 6.8 6.1 5.0 6.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Robl_LC7 PF03259.17 KFO96691.1 - 1.6e-13 50.2 0.1 1.8e-13 50.0 0.1 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain Ras PF00071.22 KFO96692.1 - 3.4e-57 192.6 0.0 3.7e-57 192.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO96692.1 - 1.4e-30 106.0 0.0 1.8e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO96692.1 - 9.5e-12 44.7 0.0 1.1e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFO96692.1 - 7.3e-07 29.3 0.0 8.8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFO96692.1 - 2e-05 24.6 0.7 0.031 14.2 0.1 2.2 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KFO96692.1 - 4.7e-05 22.9 0.0 0.00024 20.6 0.0 1.8 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFO96692.1 - 0.00038 19.9 0.0 0.00044 19.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.6 KFO96692.1 - 0.00077 19.5 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFO96692.1 - 0.0011 19.3 0.0 0.0043 17.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KFO96692.1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 KFO96692.1 - 0.0053 17.1 0.0 0.0082 16.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 KFO96692.1 - 0.0087 15.6 0.4 0.16 11.5 0.4 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B TniB PF05621.11 KFO96692.1 - 0.03 13.7 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_5 PF07728.14 KFO96692.1 - 0.032 14.2 0.0 0.053 13.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF3265 PF11665.8 KFO96692.1 - 0.039 14.2 0.3 0.065 13.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3265) cobW PF02492.19 KFO96692.1 - 0.052 13.1 0.1 0.52 9.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 KFO96692.1 - 0.055 13.2 0.0 0.1 12.3 0.0 1.6 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 KFO96692.1 - 0.056 14.0 0.0 0.063 13.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 KFO96692.1 - 0.07 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 KFO96692.1 - 0.072 13.3 0.1 1.5 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 KFO96692.1 - 0.094 12.0 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Septin PduV-EutP PF10662.9 KFO96692.1 - 0.1 12.4 0.0 0.33 10.7 0.0 1.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.14 KFO96692.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain Ras PF00071.22 KFO96693.1 - 4.4e-62 208.5 0.1 5.1e-62 208.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO96693.1 - 6.7e-35 119.9 0.1 9.4e-35 119.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO96693.1 - 1.5e-12 47.4 0.0 1.9e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFO96693.1 - 1.7e-07 31.3 0.2 3.1e-07 30.5 0.0 1.5 2 0 0 2 2 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KFO96693.1 - 5.6e-05 23.4 0.0 0.0004 20.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KFO96693.1 - 8.6e-05 22.5 0.1 0.013 15.4 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KFO96693.1 - 0.0016 18.0 0.0 0.0049 16.4 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFO96693.1 - 0.0054 17.1 0.0 0.0082 16.5 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 KFO96693.1 - 0.0062 15.9 0.0 0.009 15.4 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFO96693.1 - 0.015 14.8 0.0 0.027 13.9 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FAD-SLDH PF12318.8 KFO96693.1 - 0.017 15.2 0.1 0.027 14.5 0.1 1.3 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase ABC_tran PF00005.27 KFO96693.1 - 0.017 15.6 0.1 0.033 14.7 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 KFO96693.1 - 0.027 14.5 0.1 0.06 13.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KFO96693.1 - 0.034 13.7 0.1 0.067 12.7 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 KFO96693.1 - 0.034 13.9 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KFO96693.1 - 0.034 13.5 0.0 0.18 11.2 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein MCM PF00493.23 KFO96693.1 - 0.096 11.8 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_7 PF12775.7 KFO96693.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KFO96693.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 KFO96693.1 - 0.19 11.5 0.6 0.31 10.8 0.5 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system KH_1 PF00013.29 KFO96694.1 - 6e-22 77.3 2.1 1.7e-14 53.3 0.3 2.4 2 0 0 2 2 2 2 KH domain zf-C3HC4_3 PF13920.6 KFO96694.1 - 2e-11 43.6 9.9 3.1e-11 43.0 9.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFO96694.1 - 2.6e-05 24.4 12.4 4.4e-05 23.7 12.4 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KFO96694.1 - 3.8e-05 23.5 10.2 6.9e-05 22.6 10.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFO96694.1 - 5.4e-05 23.0 11.1 9.2e-05 22.2 11.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFO96694.1 - 0.00042 20.1 11.5 0.00074 19.3 11.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFO96694.1 - 0.024 14.7 4.2 0.024 14.7 4.2 1.9 1 1 0 1 1 1 0 RING-type zinc-finger KH_2 PF07650.17 KFO96694.1 - 0.051 13.4 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 KH domain zf-RING_5 PF14634.6 KFO96694.1 - 0.39 10.7 10.8 0.77 9.8 10.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFO96694.1 - 1.1 9.4 11.5 2.9 8.1 11.5 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KFO96694.1 - 6.1 6.7 9.6 15 5.4 9.6 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Filament PF00038.21 KFO96695.1 - 1.5e-92 310.6 68.9 2.6e-92 309.7 68.9 1.4 1 1 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 KFO96695.1 - 3.1e-16 59.7 0.0 6.1e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Lamin Tail Domain CENP-F_leu_zip PF10473.9 KFO96695.1 - 0.0009 19.3 62.6 0.0089 16.1 22.5 3.7 1 1 1 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KFO96695.1 - 0.0036 17.5 28.1 0.0036 17.5 28.1 3.9 1 1 1 3 3 3 1 Autophagy protein 16 (ATG16) TolA_bind_tri PF16331.5 KFO96695.1 - 0.01 15.9 7.2 0.01 15.9 7.2 5.1 3 2 2 5 5 5 0 TolA binding protein trimerisation TPR_MLP1_2 PF07926.12 KFO96695.1 - 0.062 13.4 63.9 2.4 8.2 9.6 4.6 2 2 2 4 4 4 0 TPR/MLP1/MLP2-like protein LPP PF04728.13 KFO96695.1 - 0.62 10.5 10.3 1.1 9.7 0.3 4.2 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Spc7 PF08317.11 KFO96695.1 - 0.77 8.6 56.9 1.4 7.7 22.7 3.4 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF1664 PF07889.12 KFO96695.1 - 1.9 8.6 28.4 1.9 8.5 4.2 4.8 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) Cnn_1N PF07989.11 KFO96695.1 - 10 6.4 41.7 0.15 12.2 1.2 5.6 1 1 3 4 4 4 0 Centrosomin N-terminal motif 1 Sema PF01403.19 KFO96696.1 - 1.2e-83 281.4 0.0 1.3e-83 281.2 0.0 1.0 1 0 0 1 1 1 1 Sema domain zf-U11-48K PF05253.12 KFO96696.1 - 0.072 13.0 0.1 0.19 11.7 0.1 1.7 1 0 0 1 1 1 0 U11-48K-like CHHC zinc finger Mito_carr PF00153.27 KFO96697.1 - 5.8e-48 160.8 5.7 3.2e-16 59.0 0.8 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein Nnf1 PF03980.14 KFO96698.1 - 1.1e-20 74.0 0.9 1.5e-20 73.6 0.9 1.2 1 0 0 1 1 1 1 Nnf1 F-box-like PF12937.7 KFO96699.1 - 0.0067 16.3 0.2 0.013 15.3 0.2 1.5 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 KFO96699.1 - 0.0085 16.1 2.8 7.2 6.9 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.7 KFO96699.1 - 0.014 15.8 3.5 0.14 12.6 1.9 2.9 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) UCH PF00443.29 KFO96700.1 - 2e-62 211.0 0.4 3.2e-62 210.3 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFO96700.1 - 4.5e-22 79.0 5.9 6.5e-21 75.2 0.0 2.8 2 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFO96700.1 - 3.1e-19 69.1 11.4 3.1e-19 69.1 11.4 3.0 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein zf-AD PF07776.15 KFO96700.1 - 5.8 7.2 14.3 1.9 8.8 3.4 3.0 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Carb_anhydrase PF00194.21 KFO96701.1 - 1.1e-85 287.2 0.0 1.3e-85 287.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Ras PF00071.22 KFO96702.1 - 3.7e-51 172.9 0.4 4.6e-51 172.6 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO96702.1 - 4.5e-22 78.5 0.1 8.3e-22 77.7 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO96702.1 - 1.2e-11 44.4 0.4 1.4e-11 44.2 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFO96702.1 - 0.00022 20.8 0.0 0.00028 20.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF3963 PF13124.6 KFO96702.1 - 0.018 15.0 0.8 0.034 14.1 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) Gtr1_RagA PF04670.12 KFO96702.1 - 0.031 13.6 0.1 0.039 13.3 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ribosomal_S27e PF01667.17 KFO96703.1 - 5.2e-30 102.9 5.3 6.3e-30 102.7 5.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 DUF3795 PF12675.7 KFO96703.1 - 0.038 14.4 2.6 0.15 12.5 2.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) Beta-lactamase PF00144.24 KFO96704.1 - 7.7e-51 173.3 0.0 2e-27 96.3 0.0 2.0 2 0 0 2 2 2 2 Beta-lactamase Peptidase_S11 PF00768.20 KFO96704.1 - 0.022 14.2 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 KFO96704.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase enzyme family Tropomyosin PF00261.20 KFO96705.1 - 9.7e-103 342.6 87.3 1.6e-98 328.9 62.3 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 KFO96705.1 - 8.1e-40 136.3 75.1 1.1e-35 122.9 42.3 3.0 1 1 0 2 2 2 2 Tropomyosin like CLZ PF16526.5 KFO96705.1 - 9.8e-07 29.0 50.5 2.2e-05 24.7 11.7 5.0 1 1 3 5 5 5 4 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Laminin_II PF06009.12 KFO96705.1 - 2.3e-06 27.6 40.1 2.4e-05 24.4 7.2 4.0 1 1 3 4 4 4 3 Laminin Domain II TMF_DNA_bd PF12329.8 KFO96705.1 - 0.00067 19.6 9.3 0.00067 19.6 9.3 6.4 2 2 4 6 6 6 2 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 KFO96705.1 - 0.0047 17.0 30.8 0.0047 17.0 30.8 2.3 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF745 PF05335.13 KFO96705.1 - 0.0052 16.5 48.0 0.22 11.2 9.7 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF745) XhlA PF10779.9 KFO96705.1 - 0.01 16.0 58.4 0.019 15.1 3.7 6.9 2 2 4 7 7 7 0 Haemolysin XhlA Laminin_I PF06008.14 KFO96705.1 - 0.011 15.4 54.7 0.15 11.8 16.7 3.1 1 1 2 3 3 3 0 Laminin Domain I MscS_porin PF12795.7 KFO96705.1 - 0.02 14.4 52.2 0.59 9.6 30.9 2.9 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain ERM PF00769.19 KFO96705.1 - 0.026 14.3 73.8 0.21 11.4 25.9 2.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family AAA_13 PF13166.6 KFO96705.1 - 0.036 12.7 50.3 0.31 9.6 12.7 2.1 1 1 1 2 2 2 0 AAA domain DUF1664 PF07889.12 KFO96705.1 - 0.06 13.4 32.2 0.17 11.9 5.1 4.0 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 KFO96705.1 - 0.13 11.7 56.5 0.39 10.1 21.0 2.8 1 1 2 3 3 3 0 Golgin subfamily A member 5 ATG16 PF08614.11 KFO96705.1 - 0.13 12.5 61.8 0.98 9.6 22.0 3.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GAS PF13851.6 KFO96705.1 - 0.22 10.9 63.5 0.2 11.0 15.6 2.9 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF16 PF01519.16 KFO96705.1 - 0.33 11.5 40.6 0.54 10.8 0.4 4.5 1 1 3 4 4 4 0 Protein of unknown function DUF16 MAD PF05557.13 KFO96705.1 - 0.55 8.5 60.0 2 6.7 23.6 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein Lebercilin PF15619.6 KFO96705.1 - 0.56 9.8 62.9 0.94 9.1 24.5 3.4 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease ADIP PF11559.8 KFO96705.1 - 0.67 10.0 52.3 2.8 8.0 8.4 4.1 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding SNARE PF05739.19 KFO96705.1 - 0.71 9.9 10.2 2.3 8.3 0.1 4.5 5 0 0 5 5 4 0 SNARE domain DUF1794 PF08768.11 KFO96705.1 - 0.73 9.8 5.6 11 6.0 0.3 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF1794) SlyX PF04102.12 KFO96705.1 - 0.96 10.1 47.6 0.38 11.4 3.6 5.5 1 1 5 6 6 5 0 SlyX Fib_alpha PF08702.10 KFO96705.1 - 1.5 9.0 35.0 0.16 12.2 6.9 3.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family HOOK PF05622.12 KFO96705.1 - 1.6 6.8 59.2 0.016 13.4 15.7 2.1 1 1 1 2 2 2 0 HOOK protein DUF3584 PF12128.8 KFO96705.1 - 1.9 5.9 58.8 1.7 6.1 24.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.15 KFO96705.1 - 2.1 7.9 37.6 1.8e+04 -10.1 37.6 2.3 1 1 0 1 1 0 0 Exonuclease VII, large subunit EzrA PF06160.12 KFO96705.1 - 3.4 5.7 56.9 0.14 10.3 9.0 3.1 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA Flagellin_C PF00700.21 KFO96705.1 - 3.8 7.9 14.2 1 9.8 1.8 4.0 1 1 3 4 4 4 0 Bacterial flagellin C-terminal helical region FH2 PF02181.23 KFO96705.1 - 3.9 6.5 38.9 0.63 9.1 9.7 3.1 1 1 2 3 3 3 0 Formin Homology 2 Domain Fmp27_WPPW PF10359.9 KFO96705.1 - 4 6.2 40.9 0.48 9.2 10.7 2.8 1 1 2 3 3 3 0 RNA pol II promoter Fmp27 protein domain NPV_P10 PF05531.12 KFO96705.1 - 4.1 7.9 20.8 12 6.4 0.8 4.5 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF4472 PF14739.6 KFO96705.1 - 4.9 7.9 53.4 1.6 9.5 10.3 4.5 1 1 5 6 6 5 0 Domain of unknown function (DUF4472) FPP PF05911.11 KFO96705.1 - 5.9 4.9 62.3 1.5 6.9 18.0 2.9 1 1 2 3 3 3 0 Filament-like plant protein, long coiled-coil DUF4200 PF13863.6 KFO96705.1 - 7.3 7.0 71.9 0.34 11.3 12.2 4.5 1 1 1 3 3 3 0 Domain of unknown function (DUF4200) TTKRSYEDQ PF10212.9 KFO96705.1 - 9.9 5.0 38.5 0.49 9.3 12.9 2.2 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein VBS PF08913.10 KFO96706.1 - 3.9e-64 214.7 0.5 3.9e-64 214.7 0.5 12.7 12 2 2 14 14 14 6 Vinculin Binding Site I_LWEQ PF01608.17 KFO96706.1 - 4.6e-64 215.3 200.2 9.9e-48 162.2 15.4 18.9 8 3 8 20 20 20 10 I/LWEQ domain Talin_middle PF09141.10 KFO96706.1 - 3.3e-51 173.5 3.3 3.3e-51 173.5 3.3 15.4 9 6 5 14 14 14 3 Talin, middle domain FERM_f0 PF16511.5 KFO96706.1 - 1.2e-37 128.0 0.0 1.4e-34 118.3 0.0 3.1 2 0 0 2 2 2 2 N-terminal or F0 domain of Talin-head FERM FERM_M PF00373.18 KFO96706.1 - 4.5e-27 94.8 0.0 3.1e-26 92.1 0.0 2.6 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.10 KFO96706.1 - 1.6e-23 82.4 2.8 1.2e-21 76.4 0.8 3.3 3 0 0 3 3 3 1 FERM N-terminal domain IRS PF02174.17 KFO96706.1 - 0.00077 19.3 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 PTB domain (IRS-1 type) ACBP PF00887.19 KFO96706.1 - 0.0012 19.0 0.1 0.019 15.2 0.0 2.9 2 0 0 2 2 2 1 Acyl CoA binding protein DUF2605 PF10792.9 KFO96706.1 - 0.087 12.8 2.0 0.55 10.2 0.5 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) ubiquitin PF00240.23 KFO96706.1 - 0.14 11.9 0.3 26 4.6 0.0 3.6 3 0 0 3 3 3 0 Ubiquitin family C2 PF00168.30 KFO96708.1 - 2.9e-08 33.9 0.0 5.6e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain VPS13_mid_rpt PF16910.5 KFO96709.1 - 2.7e-92 308.5 22.8 1.3e-68 230.9 1.3 7.4 4 2 0 4 4 4 3 Repeating coiled region of VPS13 VPS13 PF16908.5 KFO96709.1 - 4.7e-71 239.3 12.6 1.4e-68 231.2 4.8 4.8 4 0 0 4 4 4 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KFO96709.1 - 3.4e-63 212.6 10.7 6.6e-62 208.4 0.2 3.6 3 1 1 4 4 4 3 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 KFO96709.1 - 9.2e-32 110.5 0.5 3.8e-31 108.5 0.1 2.2 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 KFO96709.1 - 7.3e-21 74.4 0.1 7.3e-21 74.4 0.1 3.5 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KFO96709.1 - 7.5e-10 39.0 2.2 2.7e-09 37.2 0.0 3.2 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain WWE PF02825.20 KFO96709.1 - 0.0052 17.3 0.1 0.024 15.2 0.1 2.2 1 0 0 1 1 1 1 WWE domain Binary_toxB PF03495.14 KFO96709.1 - 0.16 12.2 0.3 17 5.7 0.0 3.4 4 0 0 4 4 4 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain zf-C4 PF00105.18 KFO96710.1 - 4.2e-33 113.6 12.9 4.2e-33 113.6 12.9 2.3 3 0 0 3 3 3 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFO96710.1 - 3.1e-24 85.7 4.5 3.1e-24 85.7 4.5 1.9 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor NARG2_C PF10505.9 KFO96711.1 - 7e-77 257.7 0.4 1.5e-76 256.7 0.4 1.6 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus Annexin PF00191.20 KFO96712.1 - 8.4e-94 307.7 10.1 3.3e-26 91.2 0.4 4.1 4 0 0 4 4 4 4 Annexin DUF2661 PF10860.8 KFO96712.1 - 0.17 12.0 0.6 5.3 7.2 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2661) Forkhead PF00250.18 KFO96713.1 - 4.5e-38 129.4 0.0 5.1e-38 129.2 0.0 1.0 1 0 0 1 1 1 1 Forkhead domain BNIP2 PF12496.8 KFO96714.1 - 4e-35 121.2 2.4 4e-35 121.2 2.4 1.5 2 0 0 2 2 2 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CRAL_TRIO_2 PF13716.6 KFO96714.1 - 7.7e-30 103.8 0.3 1.1e-29 103.4 0.3 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KFO96714.1 - 9.6e-09 35.2 0.0 1.4e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain TFIIA_gamma_N PF02268.16 KFO96715.1 - 3.7e-23 81.3 0.6 5.2e-23 80.8 0.6 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 KFO96715.1 - 1.7e-22 79.3 2.7 2.5e-22 78.7 2.7 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit OTU PF02338.19 KFO96717.1 - 8.5e-24 84.5 0.0 1.8e-23 83.4 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Presenilin PF01080.17 KFO96717.1 - 6.7 5.4 5.7 11 4.6 5.7 1.4 1 0 0 1 1 1 0 Presenilin zf-C2H2 PF00096.26 KFO96718.1 - 6.2e-15 54.7 23.2 2.5e-05 24.5 0.5 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO96718.1 - 7.7e-13 48.2 10.5 2.6e-07 30.7 2.4 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFO96718.1 - 1.5e-08 34.8 20.4 0.0016 19.1 2.1 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFO96718.1 - 0.00042 20.9 7.8 0.24 12.1 0.4 3.3 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-met PF12874.7 KFO96718.1 - 0.021 15.2 9.9 1.4 9.4 0.3 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFO96718.1 - 0.026 14.8 8.0 0.15 12.3 6.3 2.4 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-Di19 PF05605.12 KFO96718.1 - 0.22 11.9 4.5 0.088 13.1 1.5 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KFO96718.1 - 0.34 11.2 15.5 5.8 7.3 0.3 4.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding BIR PF00653.21 KFO96718.1 - 4.2 8.1 7.9 0.89 10.2 1.8 2.2 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain zf-C2H2_aberr PF17017.5 KFO96718.1 - 7.7 6.6 9.4 7.2 6.7 0.9 2.3 1 1 1 2 2 2 0 Aberrant zinc-finger LSDAT_euk PF18139.1 KFO96719.1 - 4e-122 406.8 0.0 5.7e-122 406.2 0.0 1.2 1 0 0 1 1 1 1 SLOG in TRPM TRPM_tetra PF16519.5 KFO96719.1 - 2.3e-24 85.2 5.8 2.3e-24 85.2 5.8 1.9 2 0 0 2 2 2 1 Tetramerisation domain of TRPM Ion_trans PF00520.31 KFO96719.1 - 5.5e-20 71.6 16.0 8.9e-20 70.9 16.0 1.3 1 0 0 1 1 1 1 Ion transport protein LSDAT_prok PF18171.1 KFO96719.1 - 3e-17 62.5 0.0 5.5e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote TLV_coat PF00429.19 KFO96720.1 - 0.0053 15.5 0.1 0.0057 15.4 0.1 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) DASH_Duo1 PF08651.10 KFO96720.1 - 0.019 14.8 0.1 0.024 14.4 0.1 1.1 1 0 0 1 1 1 0 DASH complex subunit Duo1 ANAPC4 PF12896.7 KFO96720.1 - 0.024 14.1 0.1 0.027 14.0 0.1 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 7tm_4 PF13853.6 KFO96721.1 - 5.2e-45 154.3 10.2 6.1e-45 154.1 10.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO96721.1 - 2.6e-25 89.3 10.2 4.3e-25 88.5 10.1 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Gsf2 PF11055.8 KFO96721.1 - 1.1 7.9 2.4 0.65 8.7 0.1 1.7 2 0 0 2 2 2 0 Glucose signalling factor 2 VWD PF00094.25 KFO96722.1 - 4.6e-31 108.2 2.4 4.6e-31 108.2 2.4 1.9 2 0 0 2 2 2 1 von Willebrand factor type D domain C8 PF08742.11 KFO96722.1 - 2.8e-19 69.3 16.8 2.8e-19 69.3 16.8 2.5 3 0 0 3 3 3 1 C8 domain TIL PF01826.17 KFO96722.1 - 3.5e-05 24.0 4.9 3.5e-05 24.0 4.9 5.0 4 1 0 4 4 4 1 Trypsin Inhibitor like cysteine rich domain VWC PF00093.18 KFO96722.1 - 0.00052 20.3 11.7 0.00052 20.3 11.7 4.4 3 2 0 3 3 3 1 von Willebrand factor type C domain Cys_knot PF00007.22 KFO96723.1 - 2.1e-10 40.8 18.3 2.1e-10 40.8 18.3 3.6 1 1 3 4 4 4 1 Cystine-knot domain VWC PF00093.18 KFO96723.1 - 3.9e-07 30.3 35.4 1.5e-05 25.2 15.4 3.7 3 1 1 4 4 4 2 von Willebrand factor type C domain TILa PF12714.7 KFO96723.1 - 0.01 15.8 8.8 0.01 15.8 8.8 4.8 4 1 1 5 5 5 0 TILa domain CUE PF02845.16 KFO96724.1 - 9e-15 54.1 0.3 2.1e-14 52.9 0.2 1.7 2 0 0 2 2 2 1 CUE domain C2 PF00168.30 KFO96724.1 - 4.8e-14 52.5 0.0 6.9e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 C2 domain UBA PF00627.31 KFO96724.1 - 0.00037 20.3 0.1 0.0008 19.3 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain HTH_8 PF02954.19 KFO96724.1 - 0.068 13.0 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Pkinase PF00069.25 KFO96725.1 - 1.2e-61 208.4 0.0 1.7e-61 207.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO96725.1 - 2.7e-33 115.3 0.0 3.6e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFO96725.1 - 8.8e-05 22.5 0.1 0.001 19.1 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFO96725.1 - 0.0011 18.0 0.2 0.0021 17.1 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFO96725.1 - 0.0042 16.5 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 KFO96725.1 - 0.014 15.0 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KFO96725.1 - 0.027 13.8 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFO96725.1 - 0.12 11.9 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Mob1_phocein PF03637.17 KFO96726.1 - 3.6e-59 199.6 5.6 4.3e-59 199.3 5.6 1.0 1 0 0 1 1 1 1 Mob1/phocein family DSPc PF00782.20 KFO96727.1 - 9.8e-45 151.6 0.0 1.5e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 KFO96727.1 - 4.1e-12 46.6 0.0 1.2e-11 45.0 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.27 KFO96727.1 - 0.00075 19.1 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KFO96727.1 - 0.066 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate CD225 PF04505.12 KFO96728.1 - 3.4e-21 75.1 0.7 5.3e-21 74.5 0.7 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein TMEM237 PF15383.6 KFO96728.1 - 0.037 13.1 0.0 0.06 12.4 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 237 Internalin_N PF12354.8 KFO96728.1 - 0.12 12.5 0.1 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal ScdA_N PF04405.14 KFO96728.1 - 0.19 11.4 0.6 0.75 9.5 0.2 2.0 1 1 1 2 2 2 0 Domain of Unknown function (DUF542) Asp PF00026.23 KFO96729.1 - 4e-128 427.3 0.0 4.6e-128 427.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFO96729.1 - 4.3e-15 56.4 0.1 2e-12 47.7 0.1 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.12 KFO96729.1 - 8.6e-07 28.7 0.2 1.6e-05 24.7 0.2 2.3 2 0 0 2 2 2 1 A1 Propeptide TAXi_C PF14541.6 KFO96729.1 - 6.8e-05 22.7 0.0 0.00019 21.2 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KFO96729.1 - 0.00019 22.0 0.3 1.8 9.3 0.1 3.2 2 1 0 2 2 2 2 Aspartyl protease 5-nucleotidase PF06189.12 KFO96730.1 - 2.4e-91 305.3 0.0 4e-91 304.6 0.0 1.3 1 1 0 1 1 1 1 5'-nucleotidase Troponin PF00992.20 KFO96731.1 - 1e-47 161.8 10.2 1.6e-47 161.1 10.2 1.3 1 0 0 1 1 1 1 Troponin DUF919 PF06034.11 KFO96731.1 - 0.013 15.3 2.3 0.013 15.3 2.3 2.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Tup_N PF08581.10 KFO96731.1 - 0.032 14.5 0.6 0.032 14.5 0.6 2.2 2 0 0 2 2 2 0 Tup N-terminal DUF2408 PF10303.9 KFO96731.1 - 0.064 13.8 6.4 0.18 12.4 6.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) TFR_dimer PF04253.15 KFO96731.1 - 0.15 12.2 0.1 0.15 12.2 0.1 1.9 2 1 0 3 3 3 0 Transferrin receptor-like dimerisation domain CENP-F_leu_zip PF10473.9 KFO96731.1 - 0.38 10.8 14.7 0.026 14.5 7.2 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 KFO96731.1 - 0.67 9.3 4.4 1 8.6 4.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 KFO96731.1 - 0.97 9.5 4.4 0.45 10.5 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 KFO96731.1 - 2.9 6.7 4.4 3.7 6.3 4.4 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein ABC_tran_CTD PF16326.5 KFO96731.1 - 6.1 7.2 11.6 4.6 7.6 7.6 2.5 2 1 0 2 2 2 0 ABC transporter C-terminal domain Cnn_1N PF07989.11 KFO96731.1 - 6.4 7.0 15.7 3.7 7.8 0.5 3.2 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 DUF4643 PF15485.6 KFO96732.1 - 2.7e-39 135.8 16.9 3.2e-39 135.6 16.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4643) Troponin PF00992.20 KFO96734.1 - 2.7e-34 118.3 41.4 1.1e-31 109.9 35.0 2.0 1 1 1 2 2 2 2 Troponin DNApol_Exo PF18136.1 KFO96734.1 - 0.72 8.9 6.6 1 8.5 6.6 1.3 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain Ndc1_Nup PF09531.10 KFO96734.1 - 5.5 5.6 8.0 6.9 5.2 8.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ribosomal_L23 PF00276.20 KFO96735.1 - 4.3e-12 46.2 1.5 6.5e-12 45.7 1.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 RNA_pol_Rpc4 PF05132.14 KFO96735.1 - 0.15 12.5 0.6 0.15 12.5 0.6 1.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 Insulin PF00049.18 KFO96736.1 - 3.4e-14 53.6 5.5 1.5e-06 29.1 2.3 2.4 1 1 1 2 2 2 2 Insulin/IGF/Relaxin family IGF2_C PF08365.11 KFO96736.1 - 6.1e-07 29.3 1.0 1.3e-06 28.3 1.0 1.6 1 0 0 1 1 1 1 Insulin-like growth factor II E-peptide Ins_beta PF03488.14 KFO96736.1 - 0.54 10.3 5.0 6 7.0 0.1 2.4 2 1 0 2 2 2 0 Nematode insulin-related peptide beta type Insulin PF00049.18 KFO96737.1 - 4.5e-24 85.2 1.0 5.8e-24 84.9 1.0 1.1 1 0 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.14 KFO96737.1 - 0.02 14.9 5.2 0.45 10.6 0.2 2.2 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type TRM13 PF05206.14 KFO96737.1 - 0.027 14.0 0.9 0.084 12.4 0.9 1.7 1 1 0 1 1 1 0 Methyltransferase TRM13 Biopterin_H PF00351.21 KFO96738.1 - 5.5e-177 587.7 0.5 7.1e-177 587.4 0.5 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase TOH_N PF12549.8 KFO96738.1 - 5.8e-22 76.9 1.3 4.5e-12 45.4 0.3 2.7 2 0 0 2 2 2 2 Tyrosine hydroxylase N terminal Tetraspanin PF00335.20 KFO96739.1 - 2.6e-13 50.2 3.7 3.2e-13 49.9 3.7 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF4131 PF13567.6 KFO96739.1 - 0.02 14.5 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF998 PF06197.13 KFO96739.1 - 0.12 12.0 4.1 0.039 13.5 1.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF998) GWT1 PF06423.12 KFO96739.1 - 0.31 11.2 3.3 0.2 11.8 1.1 1.8 1 1 0 2 2 2 0 GWT1 Tetraspanin PF00335.20 KFO96740.1 - 1.8e-39 135.8 10.2 2.7e-39 135.2 10.2 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF4064 PF13273.6 KFO96740.1 - 0.3 11.4 7.8 0.8 10.0 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) DUF4282 PF14110.6 KFO96740.1 - 4.8 8.0 11.7 14 6.5 4.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) TSSC4 PF15264.6 KFO96741.1 - 1.3e-26 93.3 0.0 3.8e-26 91.8 0.0 1.8 1 0 0 1 1 1 1 Tumour suppressing sub-chromosomal transferable candidate 4 LSDAT_euk PF18139.1 KFO96742.1 - 9.2e-50 169.5 0.0 2e-49 168.4 0.0 1.5 2 0 0 2 2 2 1 SLOG in TRPM LSDAT_prok PF18171.1 KFO96742.1 - 4.3e-14 52.2 0.0 9.1e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 KFO96742.1 - 1.4e-11 44.1 23.6 1e-10 41.3 23.6 2.2 1 1 0 1 1 1 1 Ion transport protein Mso1_Sec1_bdg PF14475.6 KFO96742.1 - 0.027 14.1 0.1 0.16 11.6 0.0 2.3 2 0 0 2 2 2 0 Sec1-binding region of Mso1 Ion_trans PF00520.31 KFO96743.1 - 1.5e-26 93.2 12.9 2e-26 92.7 12.9 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFO96743.1 - 1.1e-11 44.5 5.8 1.1e-11 44.5 5.8 2.8 2 2 1 3 3 3 1 Ion channel CD225 PF04505.12 KFO96743.1 - 0.61 10.3 0.0 0.61 10.3 0.0 3.3 3 0 0 3 3 3 0 Interferon-induced transmembrane protein RVT_1 PF00078.27 KFO96744.1 - 0.18 11.3 0.0 6.4 6.2 0.0 2.5 3 0 0 3 3 3 0 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_1 PF07690.16 KFO96745.1 - 5.4e-40 137.4 55.6 4.6e-34 117.9 38.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KFO96745.1 - 5.1e-08 31.8 18.2 1.3e-05 23.9 7.9 3.0 1 1 1 3 3 3 3 Transmembrane secretion effector MFS_1_like PF12832.7 KFO96745.1 - 1.8e-06 27.1 26.7 0.00032 19.7 26.7 2.7 1 1 0 1 1 1 1 MFS_1 like family PH_15 PF17339.2 KFO96746.1 - 7.3e-12 45.1 0.0 9.4e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 PH domain PH PF00169.29 KFO96746.1 - 1.9e-05 25.1 0.1 2.2e-05 24.9 0.1 1.1 1 0 0 1 1 1 1 PH domain NAP PF00956.18 KFO96747.1 - 6.6e-101 337.0 6.1 9.5e-101 336.5 6.1 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) tRNA-synt_1e PF01406.19 KFO96748.1 - 3.2e-100 335.4 0.0 3.2e-100 335.4 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Med7 PF05983.11 KFO96748.1 - 0.072 13.2 6.2 0.19 11.8 6.2 1.7 1 0 0 1 1 1 0 MED7 protein tRNA-synt_1c PF00749.21 KFO96748.1 - 0.17 10.8 4.6 1 8.2 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain WGG PF10273.9 KFO96748.1 - 0.19 12.4 1.3 0.56 10.9 0.2 2.4 3 0 0 3 3 3 0 Pre-rRNA-processing protein TSR2 Senescence_reg PF04520.13 KFO96748.1 - 0.71 10.7 4.4 0.21 12.4 1.0 1.8 2 0 0 2 2 2 0 Senescence regulator TNFR_c6 PF00020.18 KFO96749.1 - 3.8e-11 43.2 8.6 3.8e-11 43.2 8.6 3.4 2 1 1 3 3 3 3 TNFR/NGFR cysteine-rich region Y_phosphatase PF00102.27 KFO96750.1 - 1.5e-85 286.6 1.8 2.9e-85 285.6 1.8 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTP_tm PF18861.1 KFO96750.1 - 1.1e-82 276.6 0.1 3e-82 275.1 0.1 1.9 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J fn3 PF00041.21 KFO96750.1 - 3.5e-49 165.1 24.8 7.2e-10 39.1 0.6 7.4 7 0 0 7 7 7 6 Fibronectin type III domain Y_Y_Y PF07495.13 KFO96750.1 - 5e-13 48.8 5.5 0.073 13.0 0.1 5.6 6 0 0 6 6 6 4 Y_Y_Y domain Pur_ac_phosph_N PF16656.5 KFO96750.1 - 1.8e-10 41.2 31.0 0.15 12.7 3.0 7.3 4 2 1 6 6 6 5 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 KFO96750.1 - 2.9e-06 27.6 7.4 2 8.9 0.2 5.4 4 2 2 6 6 5 2 Uncharacterised conserved protein (DUF2369) PTPlike_phytase PF14566.6 KFO96750.1 - 0.00033 20.8 0.0 0.0054 16.9 0.0 2.9 2 1 1 3 3 3 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KFO96750.1 - 0.00035 20.6 0.0 0.00074 19.6 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KFO96750.1 - 0.00062 19.6 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CpcD PF01383.21 KFO96750.1 - 0.0011 19.2 7.2 32 4.9 0.1 5.2 5 0 0 5 5 5 0 CpcD/allophycocyanin linker domain Y_phosphatase2 PF03162.13 KFO96750.1 - 0.0026 17.3 0.1 0.0057 16.2 0.1 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF4945 PF16303.5 KFO96750.1 - 0.021 14.8 0.1 1.5e+02 2.3 0.0 4.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4945) DUF2627 PF11118.8 KFO96750.1 - 0.033 14.7 0.0 0.068 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) SARS_X4 PF08779.10 KFO96750.1 - 0.12 12.6 0.1 52 4.1 0.0 3.6 3 0 0 3 3 3 0 SARS coronavirus X4 like Y_phosphatase PF00102.27 KFO96751.1 - 1.9e-72 243.6 1.1 3.2e-72 242.9 1.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFO96751.1 - 1.2e-06 28.4 0.0 3.6e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFO96751.1 - 0.0017 18.3 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family YccF PF03733.13 KFO96751.1 - 0.0027 18.4 0.9 0.011 16.4 0.9 2.1 1 0 0 1 1 1 1 Inner membrane component domain Proton_antipo_C PF01010.19 KFO96751.1 - 0.028 14.1 0.2 0.053 13.2 0.2 1.4 1 0 0 1 1 1 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus PTPlike_phytase PF14566.6 KFO96751.1 - 0.092 12.9 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate YhhN PF07947.14 KFO96752.1 - 1.2e-45 155.5 23.7 1.2e-45 155.5 23.7 1.3 1 1 0 1 1 1 1 YhhN family YtpI PF14007.6 KFO96752.1 - 3.5 7.8 8.8 0.26 11.4 0.3 3.0 2 1 1 3 3 3 0 YtpI-like protein SPT2 PF08243.11 KFO96753.1 - 1.1e-21 77.4 24.6 1.1e-21 77.4 24.6 4.0 4 0 0 4 4 4 1 SPT2 chromatin protein UEV PF05743.13 KFO96754.1 - 6.5e-42 142.2 0.3 1e-41 141.5 0.3 1.3 1 0 0 1 1 1 1 UEV domain Ldh_1_N PF00056.23 KFO96754.1 - 4.2e-22 78.8 0.6 7.3e-22 78.0 0.6 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KFO96754.1 - 2e-13 50.6 0.0 3.9e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3HCDH_N PF02737.18 KFO96754.1 - 0.25 11.2 1.3 0.29 11.0 0.3 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UEV PF05743.13 KFO96755.1 - 5.6e-46 155.3 2.3 9.2e-46 154.6 0.2 2.1 2 0 0 2 2 2 1 UEV domain Vps23_core PF09454.10 KFO96755.1 - 3.8e-28 97.2 0.1 6.7e-28 96.4 0.1 1.4 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.26 KFO96755.1 - 0.00033 20.3 0.4 0.00094 18.8 0.4 1.8 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF3450 PF11932.8 KFO96755.1 - 0.0007 19.0 8.4 0.0012 18.2 8.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Macoilin PF09726.9 KFO96755.1 - 0.017 13.8 3.6 0.022 13.3 3.6 1.1 1 0 0 1 1 1 0 Macoilin family APG6_N PF17675.1 KFO96755.1 - 0.019 15.5 11.8 0.019 15.5 11.8 1.6 2 0 0 2 2 1 0 Apg6 coiled-coil region GPS2_interact PF15784.5 KFO96755.1 - 0.026 14.9 9.0 0.096 13.1 9.0 1.9 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF1640 PF07798.11 KFO96755.1 - 0.027 14.5 7.1 0.027 14.5 7.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) ERM PF00769.19 KFO96755.1 - 0.053 13.3 13.9 0.092 12.5 13.9 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Fzo_mitofusin PF04799.13 KFO96755.1 - 0.062 12.9 4.5 0.12 11.9 4.5 1.4 1 0 0 1 1 1 0 fzo-like conserved region Exonuc_VII_L PF02601.15 KFO96755.1 - 0.077 12.6 1.6 0.097 12.2 1.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 KFO96755.1 - 0.083 11.5 5.0 0.11 11.0 5.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Prominin PF05478.11 KFO96755.1 - 0.11 10.5 2.1 0.15 10.0 2.1 1.1 1 0 0 1 1 1 0 Prominin SlyX PF04102.12 KFO96755.1 - 0.16 12.6 12.7 0.14 12.8 3.4 3.2 2 1 1 3 3 3 0 SlyX DUF3552 PF12072.8 KFO96755.1 - 0.17 11.3 10.2 0.26 10.7 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Spc7 PF08317.11 KFO96755.1 - 0.18 10.7 10.4 0.26 10.1 10.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3492 PF11997.8 KFO96755.1 - 0.32 10.7 0.7 0.48 10.1 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) DUF3782 PF12644.7 KFO96755.1 - 0.36 11.0 5.9 5 7.4 0.0 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3782) TMPIT PF07851.13 KFO96755.1 - 0.46 9.7 3.6 0.65 9.2 3.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein Spc24 PF08286.11 KFO96755.1 - 0.52 10.6 12.7 0.81 10.0 5.2 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Fib_alpha PF08702.10 KFO96755.1 - 0.57 10.4 5.0 1 9.5 5.0 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KFO96755.1 - 0.61 10.1 4.8 1.1 9.3 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KFO96755.1 - 0.63 10.5 11.8 1 9.8 0.8 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Nsp1_C PF05064.13 KFO96755.1 - 0.97 9.3 8.1 0.79 9.5 5.5 2.1 1 1 1 2 2 2 0 Nsp1-like C-terminal region V_ATPase_I PF01496.19 KFO96755.1 - 1 7.2 3.0 1.3 6.8 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF724 PF05266.14 KFO96755.1 - 1 9.1 9.5 1.7 8.4 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Spore_III_AB PF09548.10 KFO96755.1 - 1.4 9.0 4.9 2.1 8.4 4.9 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) NPV_P10 PF05531.12 KFO96755.1 - 1.7 9.2 5.7 4.1 7.9 3.7 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.9 KFO96755.1 - 2.3 7.2 5.6 4 6.4 5.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PCRF PF03462.18 KFO96755.1 - 2.4 8.0 6.4 4.1 7.2 6.4 1.3 1 0 0 1 1 1 0 PCRF domain DivIC PF04977.15 KFO96755.1 - 2.8 7.8 14.2 1.9 8.3 2.2 2.6 1 1 1 2 2 2 0 Septum formation initiator DUF4140 PF13600.6 KFO96755.1 - 3.2 8.2 7.9 27 5.3 7.1 2.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Laminin_II PF06009.12 KFO96755.1 - 3.8 7.5 8.3 9.9 6.2 5.6 2.1 2 0 0 2 2 2 0 Laminin Domain II Prefoldin PF02996.17 KFO96755.1 - 5.2 7.0 10.3 5 7.1 2.3 2.3 1 1 1 2 2 2 0 Prefoldin subunit BRE1 PF08647.11 KFO96755.1 - 5.8 7.0 17.7 3.1 7.9 13.9 2.0 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Prefoldin_2 PF01920.20 KFO96755.1 - 7 6.7 15.0 5.5 7.0 2.8 2.4 1 1 1 2 2 2 0 Prefoldin subunit TMF_DNA_bd PF12329.8 KFO96755.1 - 8 6.5 18.1 9.9 6.2 15.8 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Ldh_1_N PF00056.23 KFO96756.1 - 6.7e-46 155.9 0.2 9.8e-46 155.3 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KFO96756.1 - 1.3e-21 77.3 0.0 3.6e-21 75.8 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 KFO96756.1 - 0.0068 16.0 0.5 0.049 13.2 0.0 2.4 3 0 0 3 3 3 1 Family 4 glycosyl hydrolase PH_TFIIH PF08567.11 KFO96757.1 - 4.6e-25 87.8 0.0 9.2e-25 86.8 0.0 1.5 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.17 KFO96757.1 - 1.7e-23 82.4 3.4 4.7e-17 61.7 0.1 3.3 3 0 0 3 3 3 2 BSD domain ANAPC4_WD40 PF12894.7 KFO96758.1 - 0.015 15.6 0.2 0.068 13.5 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain SAA PF00277.18 KFO96759.1 - 2.4e-44 150.0 8.4 2.6e-44 149.8 8.4 1.0 1 0 0 1 1 1 1 Serum amyloid A protein IKKbetaNEMObind PF12179.8 KFO96760.1 - 0.51 10.4 3.0 0.38 10.8 0.6 2.0 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain Biopterin_H PF00351.21 KFO96761.1 - 4.7e-167 555.1 0.0 5.9e-167 554.8 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 KFO96761.1 - 2.7e-07 30.2 0.0 6e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 ACT domain DUF5370 PF17340.2 KFO96761.1 - 0.035 14.0 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5370) RCC1 PF00415.18 KFO96762.1 - 3.5e-60 200.4 26.2 4.7e-11 43.1 0.1 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFO96762.1 - 2e-33 113.5 53.0 1.8e-10 40.3 0.6 8.3 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Ion_trans PF00520.31 KFO96763.1 - 6.8e-45 153.2 13.0 8.3e-45 152.9 13.0 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFO96763.1 - 3.3e-21 75.4 0.0 3.8e-16 59.2 0.0 2.7 1 1 1 2 2 2 2 BTB/POZ domain Ion_trans_2 PF07885.16 KFO96763.1 - 2.6e-11 43.3 2.6 2.6e-11 43.3 2.6 2.5 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.5 KFO96763.1 - 0.015 15.4 0.0 0.039 14.1 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain Basic PF01586.16 KFO96764.1 - 2.3e-29 102.4 3.1 2.5e-29 102.3 1.3 2.0 2 0 0 2 2 2 1 Myogenic Basic domain Myf5 PF12232.8 KFO96764.1 - 1.2e-24 86.8 11.7 1.2e-24 86.8 11.7 2.3 2 0 0 2 2 2 1 Myogenic determination factor 5 HLH PF00010.26 KFO96764.1 - 5.3e-14 51.9 3.6 1e-13 51.0 3.6 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ferritin PF00210.24 KFO96766.1 - 3.7e-16 59.3 0.7 5.3e-16 58.8 0.4 1.4 2 0 0 2 2 2 1 Ferritin-like domain ABC_membrane PF00664.23 KFO96767.1 - 1.9e-75 254.1 36.6 3.8e-41 141.6 4.9 3.0 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFO96767.1 - 6e-52 175.8 0.2 2.3e-24 86.5 0.0 3.1 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 KFO96767.1 - 3.7e-11 42.9 3.0 8.2e-05 22.1 0.0 3.2 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFO96767.1 - 1e-05 25.5 2.1 0.51 10.1 0.0 3.8 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFO96767.1 - 0.00011 22.1 0.0 0.0078 16.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KFO96767.1 - 0.00021 21.4 0.0 0.076 13.1 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KFO96767.1 - 0.00032 20.4 0.6 0.21 11.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KFO96767.1 - 0.00096 18.1 1.1 0.16 10.8 0.0 3.0 3 1 0 3 3 3 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 KFO96767.1 - 0.0017 18.0 0.0 0.09 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KFO96767.1 - 0.0026 18.3 2.4 0.4 11.1 0.5 2.8 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KFO96767.1 - 0.0038 17.3 2.2 0.04 14.0 0.0 2.8 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.6 KFO96767.1 - 0.0086 16.3 0.1 2.8 8.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KFO96767.1 - 0.024 14.3 0.2 0.58 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 KFO96767.1 - 0.028 13.9 0.0 2.1 7.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KFO96767.1 - 0.037 13.3 0.0 0.24 10.7 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin ATPase PF06745.13 KFO96767.1 - 0.043 13.1 0.1 7.1 5.9 0.0 2.5 2 0 0 2 2 2 0 KaiC ATP-synt_ab PF00006.25 KFO96767.1 - 0.073 12.7 0.1 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_16 PF13191.6 KFO96767.1 - 0.078 13.4 0.0 0.63 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 KFO96767.1 - 0.089 12.5 0.1 0.49 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Stevor PF17410.2 KFO96767.1 - 2.6 7.5 8.3 1.4 8.4 1.0 2.6 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame IRK_C PF17655.1 KFO96768.1 - 4.1e-69 231.6 0.0 5.4e-69 231.3 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFO96768.1 - 1.1e-56 190.6 0.6 1.8e-56 189.9 0.6 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain EI24 PF07264.11 KFO96768.1 - 0.04 14.1 2.0 0.075 13.3 2.0 1.4 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Cupin_2 PF07883.11 KFO96768.1 - 0.15 11.8 0.1 0.32 10.8 0.1 1.4 1 0 0 1 1 1 0 Cupin domain Ion_trans_2 PF07885.16 KFO96768.1 - 1.2 9.2 7.5 4.5 7.3 7.5 2.0 1 1 0 1 1 1 0 Ion channel EF-hand_7 PF13499.6 KFO96769.1 - 2e-11 44.2 3.4 2e-11 44.2 3.4 4.3 3 2 1 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.32 KFO96769.1 - 8.6e-09 34.3 5.2 0.00021 20.6 0.4 3.8 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 KFO96769.1 - 2.3e-07 30.2 3.1 1.3e-05 24.7 0.2 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 KFO96769.1 - 0.00043 19.7 4.1 0.0096 15.4 0.4 4.3 4 0 0 4 4 4 1 EF hand Histone_HNS PF00816.21 KFO96769.1 - 0.088 13.6 0.9 0.088 13.6 0.9 3.7 3 1 0 3 3 3 0 H-NS histone family EF-hand_8 PF13833.6 KFO96769.1 - 0.67 9.8 4.9 2.9 7.8 0.0 3.6 4 0 0 4 4 4 0 EF-hand domain pair MctB PF11382.8 KFO96769.1 - 3.1 7.4 8.7 6.5 6.4 8.7 1.4 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB SlyX PF04102.12 KFO96769.1 - 7.4 7.3 19.0 1.5 9.5 12.9 3.0 2 1 0 2 2 2 0 SlyX PI3_PI4_kinase PF00454.27 KFO96770.1 - 1.2e-58 198.9 0.3 8.8e-58 196.0 0.3 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KFO96770.1 - 1.2e-43 148.6 0.6 2.5e-43 147.6 0.6 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 KFO96770.1 - 3.2e-29 101.6 0.3 1.2e-28 99.8 0.1 2.1 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 KFO96770.1 - 5.7e-25 87.6 0.2 1.6e-24 86.1 0.2 1.8 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PX PF00787.24 KFO96770.1 - 1.8e-18 66.5 1.1 5.5e-18 65.0 0.4 2.2 2 0 0 2 2 2 1 PX domain C2 PF00168.30 KFO96770.1 - 7.5e-13 48.7 0.0 3.4e-12 46.6 0.0 2.1 2 0 0 2 2 2 1 C2 domain DUF4135 PF13575.6 KFO96770.1 - 0.011 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Ribosomal_S13_N PF08069.12 KFO96771.1 - 1.4e-16 60.2 0.1 2.8e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KFO96771.1 - 3.2e-15 56.1 1.2 5.3e-15 55.4 1.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 KFO96771.1 - 0.038 13.9 0.0 0.093 12.7 0.0 1.7 2 0 0 2 2 2 0 'Paired box' domain PH PF00169.29 KFO96772.1 - 2.3e-19 69.8 0.0 7.2e-19 68.3 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFO96772.1 - 1.4e-08 35.1 0.9 4.5e-08 33.5 0.1 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 KFO96772.1 - 2.6e-05 24.4 0.0 0.028 14.7 0.0 2.9 1 1 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 KFO96772.1 - 0.0012 19.2 0.2 0.017 15.4 0.0 2.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 KFO96772.1 - 0.0022 18.1 0.0 0.3 11.2 0.0 3.5 1 1 1 2 2 2 1 PH domain DUF3947 PF13135.6 KFO96772.1 - 0.3 11.3 1.3 1.1 9.4 1.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) HMG_box_5 PF14887.6 KFO96772.1 - 0.44 10.6 3.6 0.23 11.5 0.6 2.1 2 0 0 2 2 2 0 HMG (high mobility group) box 5 SMAP PF15477.6 KFO96773.1 - 5e-14 53.0 3.4 5e-14 53.0 3.4 2.3 2 1 0 2 2 2 1 Small acidic protein family PNISR PF15996.5 KFO96773.1 - 0.2 11.9 16.6 0.23 11.7 16.6 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Spore_coat_CotO PF14153.6 KFO96773.1 - 0.55 10.1 10.7 0.75 9.7 10.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Nop14 PF04147.12 KFO96773.1 - 1 7.5 17.5 1.2 7.3 17.5 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KFO96773.1 - 1.1 7.4 14.5 1.3 7.3 14.5 1.0 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.11 KFO96773.1 - 1.2 9.1 14.5 1.8 8.6 14.5 1.4 1 1 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DDHD PF02862.17 KFO96773.1 - 1.3 9.1 7.4 1.5 8.9 7.4 1.1 1 0 0 1 1 1 0 DDHD domain Paf1 PF03985.13 KFO96773.1 - 1.9 7.4 20.1 2.4 7.0 20.1 1.1 1 0 0 1 1 1 0 Paf1 Herpes_DNAp_acc PF04929.12 KFO96773.1 - 4.2 6.3 6.4 5.3 5.9 6.4 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Hid1 PF12722.7 KFO96773.1 - 6 4.9 13.0 6.3 4.8 13.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Smg8_Smg9 PF10220.9 KFO96773.1 - 7 4.8 10.7 7.1 4.8 10.7 1.0 1 0 0 1 1 1 0 Smg8_Smg9 HMG_box PF00505.19 KFO96774.1 - 1.5e-22 79.8 4.5 5.5e-22 78.0 4.5 2.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFO96774.1 - 2e-09 37.9 1.1 2e-09 37.9 1.1 3.4 3 0 0 3 3 3 1 HMG-box domain MPS2 PF17060.5 KFO96774.1 - 2.4 7.3 17.6 0.11 11.7 11.9 1.6 2 0 0 2 2 2 0 Monopolar spindle protein 2 DivIVA PF05103.13 KFO96774.1 - 7.5 6.6 18.3 11 6.1 13.6 2.5 2 0 0 2 2 2 0 DivIVA protein INSC_LBD PF16748.5 KFO96775.1 - 1.2e-24 85.5 4.7 2.5e-24 84.4 4.7 1.5 1 0 0 1 1 1 1 Inscuteable LGN-binding domain Arm PF00514.23 KFO96775.1 - 0.0086 16.1 0.2 0.0086 16.1 0.2 5.1 5 1 0 5 5 5 1 Armadillo/beta-catenin-like repeat Rep_2 PF01719.17 KFO96775.1 - 0.058 13.2 1.2 0.1 12.4 1.2 1.3 1 0 0 1 1 1 0 Plasmid replication protein NUC PF18510.1 KFO96775.1 - 0.23 11.9 2.0 0.51 10.8 0.5 2.1 1 1 1 2 2 2 0 Nuclease domain SPOB_ab PF14682.6 KFO96775.1 - 0.32 11.1 9.4 0.34 11.0 1.7 3.3 2 1 1 3 3 3 0 Sporulation initiation phospho-transferase B, C-terminal Calc_CGRP_IAPP PF00214.19 KFO96776.1 - 9.2e-44 148.7 0.3 1e-43 148.5 0.3 1.0 1 0 0 1 1 1 1 Calcitonin / CGRP / IAPP family p450 PF00067.22 KFO96777.1 - 1.8e-114 383.1 0.0 2e-114 382.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mlp PF03304.13 KFO96777.1 - 0.082 13.1 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Mlp lipoprotein family PDEase_I PF00233.19 KFO96778.1 - 1.7e-66 224.4 0.1 1.1e-61 208.6 0.0 2.5 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Sigma70_ner PF04546.13 KFO96778.1 - 3.4e-05 23.8 0.6 8.7e-05 22.5 0.6 1.6 1 0 0 1 1 1 1 Sigma-70, non-essential region Adaptin_N PF01602.20 KFO96779.1 - 1.6e-122 409.8 8.7 2.4e-122 409.2 8.7 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 KFO96779.1 - 7.4e-61 204.2 0.3 1.6e-60 203.1 0.3 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 KFO96779.1 - 4.6e-60 201.2 0.0 2.5e-59 198.8 0.0 2.2 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 KFO96779.1 - 4.1e-08 33.4 12.3 3.2e-05 24.0 0.1 4.2 2 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFO96779.1 - 8.6e-08 31.8 0.2 0.035 14.4 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 KFO96779.1 - 1.2e-07 32.0 4.0 0.033 14.6 0.0 6.0 5 2 3 8 8 8 3 HEAT repeats HEAT_EZ PF13513.6 KFO96779.1 - 5.2e-06 26.8 0.4 1.1 9.8 0.0 5.1 5 0 0 5 5 5 2 HEAT-like repeat Arm PF00514.23 KFO96779.1 - 0.00023 21.1 0.1 1.7 8.8 0.0 4.1 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat MMS19_N PF14500.6 KFO96779.1 - 0.00029 20.5 2.0 0.0053 16.4 0.0 3.4 2 1 2 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II DUF5578 PF17741.1 KFO96779.1 - 0.0068 15.9 4.9 0.95 8.8 0.2 3.3 1 1 2 3 3 3 2 Family of unknown function (DUF5578) Ras PF00071.22 KFO96780.1 - 1.6e-49 167.6 0.4 1.8e-49 167.4 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO96780.1 - 1.6e-12 47.7 0.0 5.5e-12 45.9 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KFO96780.1 - 2.4e-06 27.2 0.0 2.9e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KFO96780.1 - 4.1e-06 26.3 0.1 4.8e-06 26.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 KFO96780.1 - 0.0092 15.8 0.1 0.011 15.5 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Tub PF01167.18 KFO96781.1 - 8.4e-55 186.1 0.5 8.4e-55 186.1 0.5 2.2 2 1 0 2 2 2 1 Tub family Tub_N PF16322.5 KFO96781.1 - 1.2e-41 143.5 19.9 1.8e-41 142.8 19.9 1.2 1 0 0 1 1 1 1 Tubby N-terminal RIC3 PF15361.6 KFO96782.1 - 1.2e-31 110.1 0.0 2.5e-31 109.0 0.0 1.6 1 0 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 DUF1664 PF07889.12 KFO96782.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) LIM PF00412.22 KFO96783.1 - 2.4e-30 104.5 21.9 3.8e-15 55.9 8.1 2.0 2 0 0 2 2 2 2 LIM domain Bromodomain PF00439.25 KFO96784.1 - 2.2e-15 56.5 0.4 1.7e-14 53.6 0.0 2.4 2 0 0 2 2 2 1 Bromodomain zf-B_box PF00643.24 KFO96784.1 - 1e-09 38.4 29.6 7.8e-09 35.5 10.2 4.9 6 0 0 6 6 6 2 B-box zinc finger PHD PF00628.29 KFO96784.1 - 1.3e-07 31.4 7.8 1.3e-07 31.4 7.8 4.4 4 0 0 4 4 4 1 PHD-finger Ribosomal_L27A PF00828.19 KFO96785.1 - 2.1e-25 89.8 0.1 2.4e-25 89.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A HLH PF00010.26 KFO96786.1 - 3e-16 59.1 2.9 3.9e-16 58.8 2.9 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tmemb_9 PF05434.11 KFO96787.1 - 8.4e-43 145.7 5.5 1.7e-42 144.7 5.5 1.5 1 1 0 1 1 1 1 TMEM9 Asp_protease PF09668.10 KFO96788.1 - 1.3e-10 41.1 0.0 2.4e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFO96788.1 - 2.4e-07 31.2 0.0 6.2e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFO96788.1 - 3.6e-05 24.3 0.0 0.00026 21.6 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 KFO96788.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease FXa_inhibition PF14670.6 KFO96789.1 - 1e-65 217.7 159.4 2.2e-11 43.8 9.9 11.0 10 1 0 10 10 10 9 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFO96789.1 - 1.6e-40 136.6 69.3 2.7e-08 33.6 1.0 11.0 10 0 0 10 10 10 7 Complement Clr-like EGF-like EGF_CA PF07645.15 KFO96789.1 - 3.9e-27 94.2 156.4 3.3e-07 30.4 10.5 10.7 10 0 0 10 10 10 6 Calcium-binding EGF domain Ephrin_rec_like PF07699.13 KFO96789.1 - 1e-26 92.4 30.0 4.2e-15 55.2 7.1 4.5 4 0 0 4 4 4 2 Putative ephrin-receptor like EGF_3 PF12947.7 KFO96789.1 - 2.3e-22 78.9 136.6 7.6e-09 35.6 7.6 10.5 9 1 0 9 9 9 8 EGF domain CUB PF00431.20 KFO96789.1 - 5.3e-20 71.8 0.3 3.9e-19 69.0 0.0 2.4 2 0 0 2 2 2 1 CUB domain EGF PF00008.27 KFO96789.1 - 1.1e-15 57.6 131.9 0.00026 21.2 4.0 11.5 10 1 1 11 11 11 8 EGF-like domain DUF4375 PF14300.6 KFO96789.1 - 0.0013 18.9 0.6 3.8 7.8 0.1 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4375) Plasmod_Pvs28 PF06247.11 KFO96789.1 - 0.0031 17.8 19.7 0.0069 16.7 4.0 10.4 10 0 0 10 10 10 3 Pvs28 EGF domain hEGF PF12661.7 KFO96789.1 - 0.01 16.5 13.8 0.017 15.7 5.3 12.2 10 1 0 10 10 10 4 Human growth factor-like EGF DENN PF02141.21 KFO96790.1 - 5.1e-61 205.9 5.7 6.2e-61 205.6 4.4 1.8 2 0 0 2 2 2 1 DENN (AEX-3) domain RUN PF02759.19 KFO96790.1 - 5.7e-40 136.4 5.0 1.2e-19 70.6 1.8 2.7 2 0 0 2 2 2 2 RUN domain dDENN PF03455.19 KFO96790.1 - 1.8e-19 69.4 1.9 1.8e-19 69.4 1.9 3.0 3 0 0 3 3 3 1 dDENN domain uDENN PF03456.18 KFO96790.1 - 3.1e-15 56.7 0.4 9.1e-15 55.2 0.0 2.1 2 0 0 2 2 2 1 uDENN domain PLAT PF01477.23 KFO96790.1 - 1.4e-14 54.7 0.0 2.8e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 PLAT/LH2 domain SNARE_assoc PF09335.11 KFO96791.1 - 7.1e-22 78.1 6.2 7.1e-22 78.1 6.2 2.6 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF5305 PF17231.2 KFO96791.1 - 0.087 12.2 0.3 0.42 10.0 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5305) TMEM208_SND2 PF05620.11 KFO96791.1 - 0.43 10.3 6.3 0.49 10.1 0.9 2.7 2 1 1 3 3 3 0 SRP-independent targeting protein 2/TMEM208 zf-H2C2_2 PF13465.6 KFO96792.1 - 4e-35 118.7 49.2 9.4e-08 32.2 0.5 7.7 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFO96792.1 - 3.1e-30 102.9 47.6 2.3e-06 27.7 1.2 7.4 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO96792.1 - 2.4e-19 68.4 43.9 0.0029 18.3 0.6 7.5 7 0 0 7 7 7 7 C2H2-type zinc finger CopK PF11525.8 KFO96792.1 - 6.9e-07 28.8 3.8 1.7 8.4 0.0 6.0 4 2 2 6 6 6 2 Copper resistance protein K zf-C2H2_8 PF15909.5 KFO96792.1 - 1.7e-06 28.2 15.9 0.012 15.9 4.6 3.5 1 1 3 4 4 4 4 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KFO96792.1 - 3.6e-05 23.9 16.7 1.2 9.5 0.5 6.6 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KFO96792.1 - 0.00014 22.5 14.4 0.25 12.0 0.4 7.0 3 2 4 7 7 7 1 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 KFO96792.1 - 0.00022 21.4 26.2 0.1 12.7 0.4 6.2 2 1 3 6 6 6 3 Aberrant zinc-finger FecR PF04773.13 KFO96792.1 - 0.0052 17.4 3.0 0.41 11.3 0.2 3.9 2 1 0 2 2 2 1 FecR protein zf-TRAF PF02176.18 KFO96792.1 - 0.019 15.6 1.4 0.019 15.6 1.4 3.8 2 2 2 4 4 4 0 TRAF-type zinc finger Pkinase PF00069.25 KFO96793.1 - 5.4e-53 180.1 0.0 6.9e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO96793.1 - 5.3e-21 75.1 0.0 6.7e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KFO96794.1 - 9.1e-18 64.7 1.2 2.2e-17 63.5 1.2 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFO96794.1 - 0.0011 19.3 10.0 0.002 18.5 5.2 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain Herpes_US12 PF05363.12 KFO96796.1 - 4.2e-05 24.2 20.0 25 5.7 0.2 6.9 7 0 0 7 7 7 7 Herpesvirus US12 family NHL PF01436.21 KFO96796.1 - 0.58 10.3 35.9 32 4.8 0.2 7.9 8 0 0 8 8 8 0 NHL repeat Calc_CGRP_IAPP PF00214.19 KFO96797.1 - 4.3e-30 104.6 0.0 5.3e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Calcitonin / CGRP / IAPP family A_deaminase PF00962.22 KFO96798.1 - 6.7e-136 452.9 0.1 1.8e-135 451.5 0.1 1.7 1 1 0 1 1 1 1 Adenosine/AMP deaminase zf-C3HC4_3 PF13920.6 KFO96799.1 - 1.4e-10 40.8 10.7 2.4e-10 40.1 10.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFO96799.1 - 2.6e-09 37.3 14.2 4.9e-09 36.4 14.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFO96799.1 - 4.6e-09 36.0 13.4 8.2e-09 35.2 13.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFO96799.1 - 4.3e-07 29.7 10.9 9.6e-07 28.6 10.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFO96799.1 - 1.3e-06 28.1 12.5 2.6e-06 27.2 12.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFO96799.1 - 1.2e-05 25.3 11.5 2.6e-05 24.1 11.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFO96799.1 - 0.00022 21.1 14.5 0.0021 18.0 14.2 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFO96799.1 - 0.0005 20.3 13.1 0.0014 18.9 13.1 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KFO96799.1 - 0.029 14.5 12.3 0.058 13.6 11.5 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Sulfotransfer_2 PF03567.14 KFO96799.1 - 0.059 13.3 0.2 0.1 12.5 0.0 1.5 2 0 0 2 2 2 0 Sulfotransferase family Gp138_N PF18352.1 KFO96799.1 - 0.14 12.2 0.1 2 8.6 0.1 2.3 2 0 0 2 2 2 0 Phage protein Gp138 N-terminal domain zf-RING_4 PF14570.6 KFO96799.1 - 0.24 11.2 11.9 0.52 10.2 11.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KFO96799.1 - 0.48 10.5 9.3 0.99 9.5 8.5 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KFO96799.1 - 4.1 7.2 16.1 2.5 7.9 12.9 2.3 2 1 0 2 2 2 0 RING-like zinc finger Xlink PF00193.17 KFO96800.1 - 2.3e-21 76.0 0.4 4.7e-21 75.0 0.4 1.5 1 0 0 1 1 1 1 Extracellular link domain DUF4446 PF14584.6 KFO96800.1 - 0.0014 18.6 0.3 0.0026 17.7 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) Comm PF15957.5 KFO96800.1 - 0.0032 17.8 1.1 0.014 15.7 0.1 2.2 1 1 1 2 2 2 1 Commissureless OSTbeta PF15048.6 KFO96800.1 - 0.005 17.0 0.2 0.011 15.9 0.2 1.5 1 0 0 1 1 1 1 Organic solute transporter subunit beta protein DUF4834 PF16118.5 KFO96800.1 - 0.033 15.2 0.0 0.065 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Phage_holin_3_6 PF07332.11 KFO96800.1 - 0.051 13.6 1.0 0.07 13.2 0.2 1.6 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF485 PF04341.12 KFO96800.1 - 0.12 12.4 0.4 0.18 11.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 DUF4690 PF15756.5 KFO96800.1 - 3.9 8.1 6.2 0.64 10.7 0.1 2.5 2 1 1 3 3 3 0 Small Novel Rich in Cartilage MRVI1 PF05781.12 KFO96801.1 - 7.3e-212 704.8 12.8 9.9e-212 704.4 12.8 1.2 1 0 0 1 1 1 1 MRVI1 protein TPR_1 PF00515.28 KFO96802.1 - 1.7e-42 141.6 39.9 8.5e-05 22.2 0.1 13.4 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_2 PF07719.17 KFO96802.1 - 5.3e-40 132.3 47.9 9.5e-05 22.2 0.0 15.6 15 0 0 15 15 15 9 Tetratricopeptide repeat TPR_19 PF14559.6 KFO96802.1 - 5.3e-38 129.4 13.8 1.3e-05 25.6 0.0 10.4 7 2 5 12 12 12 7 Tetratricopeptide repeat TPR_8 PF13181.6 KFO96802.1 - 1.1e-33 112.6 32.6 0.00041 20.3 0.0 13.5 14 0 0 14 14 12 7 Tetratricopeptide repeat TPR_16 PF13432.6 KFO96802.1 - 1e-31 109.3 16.9 8.3e-06 26.4 0.1 11.4 9 2 2 11 11 11 6 Tetratricopeptide repeat TPR_14 PF13428.6 KFO96802.1 - 6e-31 104.5 17.9 0.004 17.9 0.0 14.6 7 4 7 14 14 14 6 Tetratricopeptide repeat TPR_12 PF13424.6 KFO96802.1 - 2.3e-26 91.9 35.9 1.6e-06 28.3 0.3 10.6 7 4 1 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.6 KFO96802.1 - 6.7e-23 79.4 30.3 0.078 13.4 0.4 15.1 17 1 1 18 18 16 7 Tetratricopeptide repeat TPR_10 PF13374.6 KFO96802.1 - 3.2e-16 58.6 28.2 0.089 12.7 0.2 12.2 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFO96802.1 - 4e-16 58.4 27.0 2.5e-05 23.9 0.0 12.0 11 3 2 13 13 13 4 TPR repeat TPR_6 PF13174.6 KFO96802.1 - 8.8e-16 57.4 33.3 0.0059 17.2 0.0 13.1 14 0 0 14 14 13 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFO96802.1 - 3.9e-13 48.4 31.8 0.024 14.6 0.1 12.2 13 0 0 13 13 12 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO96802.1 - 1.9e-07 31.2 30.7 0.11 12.7 0.2 7.1 5 2 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KFO96802.1 - 7.5e-07 29.2 2.4 2.1 8.6 0.0 6.4 5 2 2 7 7 7 2 Tetratricopeptide repeat PknG_TPR PF16918.5 KFO96802.1 - 0.00046 19.0 1.9 0.76 8.5 0.2 4.2 3 1 1 4 4 4 1 Protein kinase G tetratricopeptide repeat TPPII_N PF12583.8 KFO96802.1 - 0.057 14.0 13.3 0.2 12.2 0.2 4.9 5 0 0 5 5 4 0 Tripeptidyl peptidase II N terminal Rapsyn_N PF10579.9 KFO96802.1 - 0.66 10.1 11.4 2.7 8.2 0.0 5.0 5 1 0 5 5 4 0 Rapsyn N-terminal myristoylation and linker region DUF4810 PF16068.5 KFO96802.1 - 2.8 8.6 9.9 12 6.6 0.0 4.5 4 0 0 4 4 2 0 Domain of unknown function (DUF4810) Tcf25 PF04910.14 KFO96802.1 - 3.8 6.5 9.6 0.38 9.8 0.1 3.4 3 1 0 4 4 4 0 Transcriptional repressor TCF25 TPR_3 PF07720.12 KFO96802.1 - 8 6.6 22.3 6 7.0 5.3 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Complex1_LYR_2 PF13233.6 KFO96802.1 - 8.5 7.2 15.2 18 6.1 0.0 4.8 5 0 0 5 5 4 0 Complex1_LYR-like MIF4G PF02854.19 KFO96803.1 - 1.3e-57 194.9 2.5 1.3e-57 194.9 2.5 2.3 2 0 0 2 2 2 1 MIF4G domain W2 PF02020.18 KFO96803.1 - 1.1e-20 73.6 1.6 3.5e-20 71.9 1.0 2.3 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon MA3 PF02847.17 KFO96803.1 - 7.6e-16 58.1 0.2 7.6e-16 58.1 0.2 3.1 3 0 0 3 3 3 1 MA3 domain Glycos_transf_2 PF00535.26 KFO96806.1 - 6.3e-25 87.9 0.0 8.6e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 KFO96806.1 - 0.00028 20.5 0.0 0.00071 19.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Ricin_B_lectin PF00652.22 KFO96806.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain UCH PF00443.29 KFO96807.1 - 2.2e-49 168.3 0.6 5e-49 167.1 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFO96807.1 - 1.6e-38 133.1 1.0 4.2e-38 131.7 1.0 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_2 PF14560.6 KFO96807.1 - 8.7e-08 32.5 0.1 0.14 12.6 0.0 4.1 3 0 0 3 3 3 3 Ubiquitin-like domain ubiquitin PF00240.23 KFO96807.1 - 3e-07 30.1 0.2 0.15 11.8 0.0 3.9 3 0 0 3 3 3 2 Ubiquitin family DUF4487 PF14868.6 KFO96807.1 - 0.022 13.6 0.2 0.043 12.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4487) Sad1_UNC PF07738.13 KFO96807.1 - 0.036 14.1 0.0 0.099 12.7 0.0 1.7 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Dickkopf_N PF04706.12 KFO96808.1 - 8.5e-16 58.2 20.0 8.5e-16 58.2 20.0 3.3 3 0 0 3 3 3 2 Dickkopf N-terminal cysteine-rich region Prokineticin PF06607.11 KFO96808.1 - 1.3e-05 25.4 3.2 1.3e-05 25.4 3.2 2.8 1 1 2 3 3 3 1 Prokineticin CH PF00307.31 KFO96809.1 - 5.1e-35 120.0 3.2 2.5e-18 66.2 1.0 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFO96809.1 - 1.3e-05 24.9 0.0 0.066 13.0 0.0 2.6 2 0 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.11 KFO96809.1 - 2.5e-05 24.3 0.2 0.041 14.0 0.0 2.5 2 0 0 2 2 2 2 CH-like domain in sperm protein FlaG PF03646.15 KFO96809.1 - 0.21 11.8 3.0 0.12 12.5 0.7 1.8 2 0 0 2 2 2 0 FlaG protein Sfi1 PF08457.10 KFO96809.1 - 0.31 9.5 1.7 0.22 10.0 0.3 1.3 2 0 0 2 2 2 0 Sfi1 spindle body protein YBD PF17725.1 KFO96810.1 - 7.7e-100 332.9 1.2 1e-99 332.6 1.2 1.1 1 0 0 1 1 1 1 YAP binding domain TEA PF01285.18 KFO96810.1 - 2.2e-27 94.9 0.0 4.4e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 TEA/ATTS domain PAS_11 PF14598.6 KFO96811.1 - 1.2e-26 93.1 0.4 9.3e-23 80.5 0.2 2.3 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 KFO96811.1 - 4.3e-20 71.8 0.0 1e-08 35.2 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 KFO96811.1 - 6.4e-20 71.2 0.0 8.5e-12 45.2 0.0 2.4 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 KFO96811.1 - 2.6e-16 59.3 0.8 4.4e-16 58.6 0.8 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 KFO96811.1 - 1.9e-08 34.5 0.0 7.9e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KFO96811.1 - 3.2e-05 24.2 0.0 0.01 16.1 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.11 KFO96811.1 - 0.025 15.2 0.0 0.098 13.3 0.0 1.9 2 0 0 2 2 2 0 PAS fold BTB_3 PF16017.5 KFO96812.1 - 1.5e-50 169.7 0.0 2.8e-50 168.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 KFO96812.1 - 0.00069 19.9 0.0 0.0018 18.6 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Parathyroid PF01279.17 KFO96813.1 - 1.5e-07 32.0 1.1 1.9e-07 31.7 1.1 1.2 1 0 0 1 1 1 1 Parathyroid hormone family NAD_binding_4 PF07993.12 KFO96814.1 - 8.3e-78 261.1 0.0 1.1e-77 260.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 KFO96814.1 - 2.3e-30 104.6 1.8 5.4e-30 103.5 1.8 1.7 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KFO96814.1 - 8.8e-08 31.9 0.0 3.4e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFO96814.1 - 6.7e-05 22.4 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KFO96814.1 - 0.0013 17.9 0.0 0.0033 16.6 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KFO96814.1 - 0.0018 17.4 0.0 0.13 11.2 0.0 2.7 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KFO96814.1 - 0.027 14.9 0.0 0.052 14.0 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_1 PF00175.21 KFO96815.1 - 1.5e-36 125.4 0.0 3.1e-36 124.3 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KFO96815.1 - 2.9e-36 123.8 0.0 4.9e-36 123.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KFO96815.1 - 1.1e-05 25.6 0.0 0.00016 21.9 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KFO96815.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain SAM_1 PF00536.30 KFO96816.1 - 2.2e-41 140.1 6.1 7.1e-19 68.0 0.1 4.2 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFO96816.1 - 3.2e-39 132.9 4.0 5.3e-15 55.3 0.0 4.0 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) Myosin_tail_1 PF01576.19 KFO96816.1 - 6.6e-05 21.0 27.7 9.2e-05 20.5 27.7 1.1 1 0 0 1 1 1 1 Myosin tail DUF4007 PF13182.6 KFO96816.1 - 0.0046 16.1 0.9 0.0099 15.0 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4007) HMMR_N PF15905.5 KFO96816.1 - 0.01 15.3 8.6 0.01 15.3 8.6 2.4 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal PKcGMP_CC PF16808.5 KFO96816.1 - 0.014 15.2 1.7 0.014 15.2 1.7 4.8 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SAM_PNT PF02198.16 KFO96816.1 - 0.12 12.3 3.8 5.1 7.1 0.1 3.4 3 0 0 3 3 3 0 Sterile alpha motif (SAM)/Pointed domain ADIP PF11559.8 KFO96816.1 - 0.13 12.4 28.5 0.72 9.9 17.5 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding zf-C4H2 PF10146.9 KFO96816.1 - 0.15 12.3 7.8 0.39 11.0 7.8 1.8 1 0 0 1 1 1 0 Zinc finger-containing protein DUF1192 PF06698.11 KFO96816.1 - 0.18 11.9 3.4 0.9 9.6 3.4 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF16 PF01519.16 KFO96816.1 - 3.2 8.3 19.8 0.053 14.0 2.5 3.3 2 1 0 3 3 2 0 Protein of unknown function DUF16 Atg14 PF10186.9 KFO96816.1 - 6.1 5.8 27.3 0.17 10.9 18.0 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Mab-21 PF03281.14 KFO96817.1 - 4.9e-13 49.0 1.0 1.7e-11 44.0 1.0 2.1 1 1 0 1 1 1 1 Mab-21 protein C2 PF00168.30 KFO96818.1 - 5.1e-53 177.7 0.1 1.8e-26 92.4 0.1 2.3 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 KFO96818.1 - 0.001 19.0 0.0 0.64 9.9 0.0 3.1 3 0 0 3 3 3 2 Phosphoinositide 3-kinase C2 CEP76-C2 PF15627.6 KFO96818.1 - 0.023 14.3 0.0 3.8 7.0 0.0 2.5 2 0 0 2 2 2 0 CEP76 C2 domain NT-C2 PF10358.9 KFO96818.1 - 0.058 13.1 0.1 0.31 10.8 0.0 2.2 2 0 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins TSP_1 PF00090.19 KFO96819.1 - 1.5e-84 278.0 94.2 3.2e-17 62.5 6.9 6.9 7 0 0 7 7 7 6 Thrombospondin type 1 domain Spond_N PF06468.13 KFO96819.1 - 8e-72 241.4 0.2 1.7e-71 240.3 0.2 1.6 1 0 0 1 1 1 1 Spondin_N Reeler PF02014.16 KFO96819.1 - 2.6e-22 79.9 0.0 5.3e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Reeler domain RRN9 PF10680.9 KFO96819.1 - 3.8 7.9 7.1 10 6.5 2.4 2.9 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor DUF3827 PF12877.7 KFO96820.1 - 2.3e-292 971.5 6.2 2.3e-292 971.5 6.2 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF3827) Pkinase PF00069.25 KFO96821.1 - 1.7e-48 165.3 0.0 3.8e-48 164.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO96821.1 - 1e-23 84.0 0.0 1.8e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFO96821.1 - 5.9e-06 25.8 0.0 1.1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFO96821.1 - 0.0019 17.0 0.3 0.0045 15.8 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFO96821.1 - 0.0049 16.8 0.1 0.012 15.6 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFO96821.1 - 0.092 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KFO96821.1 - 0.15 11.6 0.2 3.8 7.1 0.1 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Suf PF05843.14 KFO96822.1 - 1.8e-84 284.3 13.6 5.8e-83 279.3 0.2 5.1 4 2 1 5 5 5 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KFO96822.1 - 4.5e-06 27.0 1.1 0.095 13.6 0.0 5.5 4 2 1 5 5 5 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KFO96822.1 - 8.3e-06 25.2 13.2 0.24 10.5 0.1 5.7 3 2 4 7 7 7 5 NRDE-2, necessary for RNA interference TPR_6 PF13174.6 KFO96822.1 - 0.0016 18.9 3.3 0.085 13.5 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFO96822.1 - 0.0063 17.0 1.7 0.11 13.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFO96822.1 - 0.099 13.3 0.6 0.58 10.9 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat HAT PF02184.16 KFO96822.1 - 7.3 6.6 7.5 13 5.9 0.0 4.5 5 0 0 5 5 5 0 HAT (Half-A-TPR) repeat Tcp11 PF05794.13 KFO96823.1 - 1.3e-111 373.8 0.0 1.5e-111 373.6 0.0 1.0 1 0 0 1 1 1 1 T-complex protein 11 DUF1819 PF08849.11 KFO96823.1 - 0.047 13.5 0.1 0.094 12.5 0.1 1.4 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) DEP PF00610.21 KFO96824.1 - 4.4e-16 58.7 1.5 3.2e-15 55.9 0.2 2.6 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Gla PF00594.20 KFO96825.1 - 6.2e-19 67.9 7.7 6.2e-19 67.9 7.7 1.6 2 0 0 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain WBP-1 PF11669.8 KFO96825.1 - 0.0092 16.6 0.0 0.02 15.5 0.0 1.5 1 0 0 1 1 1 1 WW domain-binding protein 1 DUF1810 PF08837.11 KFO96825.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1810) TMEM154 PF15102.6 KFO96825.1 - 0.044 13.7 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family TMEM190 PF15431.6 KFO96825.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 190 EBP PF05241.12 KFO96825.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.3 1 1 0 1 1 1 0 Emopamil binding protein WT1 PF02165.15 KFO96827.1 - 7.3e-160 531.0 10.0 1.1e-159 530.4 10.0 1.3 1 0 0 1 1 1 1 Wilm's tumour protein zf-H2C2_2 PF13465.6 KFO96827.1 - 2.9e-16 59.1 31.0 6.4e-07 29.5 2.9 4.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFO96827.1 - 6.7e-15 54.6 38.4 1.7e-05 25.0 3.1 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO96827.1 - 2.9e-07 30.7 33.2 0.0056 17.4 1.8 5.0 4 0 0 4 4 4 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFO96827.1 - 0.00029 21.4 12.0 0.0052 17.4 0.5 4.0 2 1 2 4 4 4 2 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 KFO96827.1 - 0.0027 17.9 6.5 0.58 10.3 0.0 3.3 2 1 0 3 3 3 2 Aberrant zinc-finger zf-C2H2_8 PF15909.5 KFO96827.1 - 0.0058 16.9 12.6 0.049 13.9 2.8 2.9 1 1 2 3 3 3 1 C2H2-type zinc ribbon zf-met PF12874.7 KFO96827.1 - 0.044 14.2 2.0 0.044 14.2 2.0 4.7 5 0 0 5 5 5 0 Zinc-finger of C2H2 type C1-set PF07654.15 KFO96827.1 - 0.072 13.5 1.0 6.8 7.1 0.1 2.8 2 0 0 2 2 2 0 Immunoglobulin C1-set domain zf-C2H2_jaz PF12171.8 KFO96827.1 - 0.28 11.5 16.0 0.13 12.6 1.5 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding CCAP PF11105.8 KFO96827.1 - 4.3 7.3 5.6 0.38 10.7 0.4 1.8 2 0 0 2 2 2 0 Arthropod cardioacceleratory peptide 2a zinc_ribbon_4 PF13717.6 KFO96827.1 - 4.3 7.3 8.1 39 4.3 0.0 3.6 4 0 0 4 4 4 0 zinc-ribbon domain MCM_OB PF17207.3 KFO96827.1 - 7.5 6.4 10.9 10 6.0 3.3 2.9 1 1 1 2 2 2 0 MCM OB domain EF-hand_1 PF00036.32 KFO96828.1 - 7.7e-18 62.7 18.1 0.0039 16.6 0.1 6.8 6 1 0 6 6 6 6 EF hand EF-hand_6 PF13405.6 KFO96828.1 - 3.7e-17 60.7 13.7 0.0023 17.7 0.0 6.4 6 0 0 6 6 6 5 EF-hand domain EF-hand_7 PF13499.6 KFO96828.1 - 1.7e-15 57.2 16.2 3.9e-07 30.4 0.3 4.3 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KFO96828.1 - 3.6e-10 38.9 23.9 0.0021 17.4 0.7 6.7 6 1 0 6 6 6 4 EF hand EF-hand_8 PF13833.6 KFO96828.1 - 2e-05 24.4 17.5 0.21 11.5 0.3 6.1 6 2 2 8 8 8 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFO96828.1 - 0.0035 17.7 9.6 0.89 9.9 0.1 3.5 3 1 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region PAX PF00292.18 KFO96829.1 - 4.2e-45 152.7 0.2 8e-45 151.8 0.2 1.4 1 0 0 1 1 1 1 'Paired box' domain Homeodomain PF00046.29 KFO96829.1 - 6.8e-23 80.3 4.5 1.2e-22 79.5 4.5 1.4 1 0 0 1 1 1 1 Homeodomain HTH_32 PF13565.6 KFO96829.1 - 0.00081 20.0 1.9 0.0033 18.0 0.0 2.4 2 1 0 2 2 2 1 Homeodomain-like domain Homeobox_KN PF05920.11 KFO96829.1 - 0.13 12.2 1.1 0.21 11.5 0.1 1.9 2 0 0 2 2 2 0 Homeobox KN domain PAXNEB PF05625.11 KFO96830.1 - 3.4e-94 316.0 0.1 3.7e-94 315.9 0.1 1.0 1 0 0 1 1 1 1 PAXNEB protein Peptidase_S24 PF00717.23 KFO96831.1 - 1.8e-12 47.0 0.0 3e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KFO96831.1 - 1.9e-07 30.9 0.0 0.00061 19.6 0.0 2.8 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 DnaJ PF00226.31 KFO96832.1 - 2.7e-17 62.6 0.4 3.8e-17 62.2 0.4 1.2 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 KFO96832.1 - 2.2e-12 46.5 6.4 3.9e-12 45.7 6.4 1.5 1 0 0 1 1 1 1 CSL zinc finger Metallophos PF00149.28 KFO96834.1 - 1.9e-11 44.9 0.8 2.8e-11 44.3 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFO96834.1 - 0.0004 20.6 0.0 0.011 16.0 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ARF7EP_C PF14949.6 KFO96835.1 - 1.4e-36 125.3 5.8 3.2e-36 124.1 5.8 1.6 1 0 0 1 1 1 1 ARF7 effector protein C-terminus Cys_knot PF00007.22 KFO96836.1 - 5e-31 107.1 18.5 6.3e-31 106.8 18.5 1.1 1 0 0 1 1 1 1 Cystine-knot domain Ion_trans PF00520.31 KFO96837.1 - 2.1e-49 167.9 9.7 2.9e-49 167.5 9.7 1.1 1 0 0 1 1 1 1 Ion transport protein K_channel_TID PF07941.11 KFO96837.1 - 1.6e-33 115.0 16.9 3.4e-33 114.0 16.9 1.6 1 0 0 1 1 1 1 Potassium channel Kv1.4 tandem inactivation domain BTB_2 PF02214.22 KFO96837.1 - 1.6e-27 95.7 0.0 4e-27 94.4 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFO96837.1 - 2.3e-13 49.9 4.9 2.3e-13 49.9 4.9 2.3 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.12 KFO96837.1 - 0.0083 14.9 0.3 0.0083 14.9 0.3 1.9 1 1 1 2 2 2 1 Polycystin cation channel Sigma_reg_N PF13800.6 KFO96837.1 - 0.15 12.4 3.9 8.3 6.8 0.0 3.5 3 0 0 3 3 3 0 Sigma factor regulator N-terminal RPN2_C PF18004.1 KFO96837.1 - 4.6 7.1 8.8 7.1 6.5 2.3 2.3 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Methyltransf_5 PF01795.19 KFO96838.1 - 3.5e-81 273.1 0.0 1.7e-80 270.9 0.0 1.8 1 1 0 1 1 1 1 MraW methylase family Methyltransf_25 PF13649.6 KFO96838.1 - 0.001 19.7 0.0 0.012 16.2 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFO96838.1 - 0.0014 18.5 0.0 0.75 9.6 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KFO96838.1 - 0.0044 17.6 0.0 0.33 11.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFO96838.1 - 0.014 16.2 0.0 1.2 9.9 0.0 3.0 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_15 PF09445.10 KFO96838.1 - 0.046 13.3 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltr_RsmB-F PF01189.17 KFO96838.1 - 0.075 12.7 0.0 0.17 11.5 0.0 1.6 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F Met_10 PF02475.16 KFO96838.1 - 0.19 11.4 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Kinesin PF00225.23 KFO96839.1 - 4.3e-115 384.2 0.7 4.3e-115 384.2 0.7 3.2 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KFO96839.1 - 2.1e-24 86.1 0.2 7.8e-24 84.3 0.2 2.0 1 0 0 1 1 1 1 Microtubule binding DUF2443 PF10398.9 KFO96839.1 - 1.3 9.2 5.0 2.3 8.3 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2443) NGF PF00243.18 KFO96840.1 - 1.7e-46 157.1 2.4 2.2e-46 156.7 2.4 1.2 1 0 0 1 1 1 1 Nerve growth factor family Spaetzle PF16077.5 KFO96840.1 - 7.6e-05 23.2 0.9 0.00011 22.7 0.9 1.2 1 0 0 1 1 1 1 Spaetzle L27 PF02828.16 KFO96841.1 - 5.5e-23 80.5 0.3 1.3e-22 79.3 0.2 1.7 2 0 0 2 2 2 1 L27 domain PDZ PF00595.24 KFO96841.1 - 4.7e-21 74.9 0.6 6.9e-21 74.4 0.6 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFO96841.1 - 1.3e-13 50.6 0.6 2.6e-13 49.6 0.2 1.7 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KFO96841.1 - 0.0044 17.3 0.0 0.0073 16.6 0.0 1.3 1 0 0 1 1 1 1 PDZ domain His_Phos_2 PF00328.22 KFO96841.1 - 0.084 12.2 0.0 0.091 12.1 0.0 1.3 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) LRR_8 PF13855.6 KFO96842.1 - 2.7e-69 228.8 46.4 3.9e-17 61.7 3.7 7.7 3 2 5 8 8 8 8 Leucine rich repeat LRR_5 PF13306.6 KFO96842.1 - 2.5e-42 143.9 0.0 7.4e-13 48.6 0.0 4.2 1 1 4 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFO96842.1 - 8.2e-35 118.3 41.2 4.2e-07 30.2 0.3 9.4 4 2 5 10 10 10 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFO96842.1 - 2e-16 60.0 9.1 4.1e-06 26.4 0.9 3.7 1 1 1 3 3 3 3 Leucine-rich repeat 7tm_1 PF00001.21 KFO96842.1 - 9.5e-13 48.1 10.7 1.5e-12 47.4 10.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_1 PF00560.33 KFO96842.1 - 4.5e-10 38.6 31.4 2.2 9.2 0.0 12.5 13 1 0 13 13 13 4 Leucine Rich Repeat Sigma70_r4 PF04545.16 KFO96842.1 - 0.059 12.9 0.1 0.15 11.6 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 LRR_6 PF13516.6 KFO96842.1 - 1.3 9.2 40.6 0.26 11.4 0.2 9.7 11 0 0 11 11 11 0 Leucine Rich repeat DUF4207 PF13904.6 KFO96843.1 - 3.7e-32 112.0 43.2 4.5e-32 111.7 43.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) Borrelia_P83 PF05262.11 KFO96843.1 - 0.0017 16.9 23.4 0.0018 16.9 23.4 1.0 1 0 0 1 1 1 1 Borrelia P83/100 protein N6_N4_Mtase PF01555.18 KFO96843.1 - 0.28 10.8 10.9 0.31 10.7 10.9 1.1 1 0 0 1 1 1 0 DNA methylase Presenilin PF01080.17 KFO96843.1 - 0.3 9.8 10.6 0.33 9.7 10.6 1.2 1 0 0 1 1 1 0 Presenilin DUF572 PF04502.13 KFO96843.1 - 1.5 8.3 27.2 2.1 7.9 27.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ndc1_Nup PF09531.10 KFO96843.1 - 1.5 7.4 9.9 1.6 7.3 9.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mit_ribos_Mrp51 PF11709.8 KFO96843.1 - 5.5 6.5 21.5 7.3 6.1 21.5 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit TauD PF02668.16 KFO96844.1 - 7.5e-42 144.0 0.0 9.6e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KFO96844.1 - 1.9e-18 66.9 0.5 2.9e-16 59.9 0.1 2.3 2 1 1 3 3 3 2 Protein of unknown function (DUF971) CsiD PF08943.10 KFO96844.1 - 6.6e-05 22.2 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 CsiD Raf1_N PF18578.1 KFO96844.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Rubisco accumulation factor 1 alpha helical domain Fibin PF15819.5 KFO96845.1 - 3.9e-74 248.6 0.1 4.3e-74 248.4 0.1 1.0 1 0 0 1 1 1 1 Fin bud initiation factor homologue SSF PF00474.17 KFO96846.1 - 3.2e-38 131.7 23.2 4.1e-38 131.3 23.2 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family NdhL PF10716.9 KFO96846.1 - 0.27 11.2 4.8 0.11 12.4 0.4 2.7 3 1 0 3 3 3 0 NADH dehydrogenase transmembrane subunit Yae1_N PF09811.9 KFO96847.1 - 7.7e-18 63.9 63.5 1.8e+04 -28.3 63.5 6.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal CALCOCO1 PF07888.11 KFO96848.1 - 0.14 11.0 31.9 0.2 10.5 31.9 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like CmlA_N PF18456.1 KFO96848.1 - 0.3 10.4 8.9 0.11 11.8 1.4 2.2 1 1 1 2 2 2 0 Diiron non-heme beta-hydroxylase N-terminal domain Leu_zip PF15294.6 KFO96848.1 - 0.37 10.3 32.7 0.028 13.9 9.1 2.0 1 1 1 2 2 2 0 Leucine zipper YkyA PF10368.9 KFO96848.1 - 0.55 9.9 34.1 0.05 13.3 20.5 2.3 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Filament PF00038.21 KFO96848.1 - 1 8.9 29.8 7.2 6.1 4.3 2.9 1 1 2 3 3 3 0 Intermediate filament protein MAD PF05557.13 KFO96848.1 - 1.8 6.8 32.0 2.1 6.6 32.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein V_ATPase_I PF01496.19 KFO96848.1 - 2.6 5.9 18.5 0.51 8.2 14.9 1.5 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF1612 PF07756.12 KFO96848.1 - 3.5 7.9 7.6 54 4.0 0.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1612) DUF3584 PF12128.8 KFO96848.1 - 4.7 4.6 28.8 8 3.8 28.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) TMEM192 PF14802.6 KFO96848.1 - 5.3 6.1 8.6 32 3.5 8.6 2.0 1 1 0 1 1 1 0 TMEM192 family DHR10 PF18595.1 KFO96848.1 - 5.4 7.1 37.0 1.3 9.1 20.2 3.0 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain YfcL PF08891.11 KFO96848.1 - 5.5 7.4 8.7 15 6.0 1.9 2.9 2 1 1 3 3 3 0 YfcL protein TPR_MLP1_2 PF07926.12 KFO96848.1 - 6.2 6.9 36.3 0.27 11.3 20.3 2.9 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.10 KFO96848.1 - 7.4 6.8 22.6 1.4 9.1 14.0 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4047 PF13256.6 KFO96848.1 - 8.4 6.6 14.2 3.7 7.7 0.9 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4047) GAS2 PF02187.17 KFO96849.1 - 1.1e-27 96.0 0.1 1.8e-27 95.2 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.31 KFO96849.1 - 3.4e-14 52.9 0.0 5e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain FANCF PF11107.8 KFO96850.1 - 1.4e-104 350.1 0.0 1.5e-104 349.9 0.0 1.0 1 0 0 1 1 1 1 Fanconi anemia group F protein (FANCF) HTH_41 PF14502.6 KFO96850.1 - 0.16 11.7 0.6 0.31 10.7 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain MFS_1 PF07690.16 KFO96851.1 - 2.3e-50 171.5 24.0 7.8e-49 166.5 22.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 KFO96851.1 - 0.094 10.9 4.9 0.42 8.8 0.0 2.9 3 0 0 3 3 3 0 BT1 family Anoctamin PF04547.12 KFO96852.1 - 1.2e-166 555.0 20.9 1.5e-166 554.7 20.9 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KFO96852.1 - 3e-65 220.1 0.0 4.7e-65 219.5 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Ctr PF04145.15 KFO96852.1 - 0.11 13.2 3.3 0.35 11.5 0.4 3.0 3 0 0 3 3 3 0 Ctr copper transporter family EGF_CA PF07645.15 KFO96853.1 - 1.4e-26 92.4 54.0 2.4e-11 43.6 5.1 10.8 9 2 2 11 11 6 4 Calcium-binding EGF domain VWC PF00093.18 KFO96853.1 - 9.5e-16 57.9 76.4 3.6e-09 36.8 14.8 9.9 6 1 3 9 9 7 5 von Willebrand factor type C domain EGF_3 PF12947.7 KFO96853.1 - 2.4e-12 46.8 35.7 3.2e-09 36.8 13.5 10.9 10 1 0 10 10 8 4 EGF domain cEGF PF12662.7 KFO96853.1 - 1e-08 35.0 11.9 1.7e-06 27.8 1.9 10.9 11 0 0 11 11 11 5 Complement Clr-like EGF-like Laminin_G_2 PF02210.24 KFO96853.1 - 2e-08 34.9 0.0 3.5e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.6 KFO96853.1 - 9.4e-07 29.1 0.0 1.5e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 KFO96853.1 - 5.7e-06 26.5 35.9 0.001 19.3 3.8 11.1 12 0 0 12 12 7 4 EGF-like domain Laminin_G_1 PF00054.23 KFO96853.1 - 5.3e-05 23.5 0.0 0.00014 22.0 0.0 1.7 1 1 0 1 1 1 1 Laminin G domain hEGF PF12661.7 KFO96853.1 - 9.9e-05 22.8 29.9 0.0013 19.3 4.9 12.3 12 1 0 12 12 9 5 Human growth factor-like EGF EGF_2 PF07974.13 KFO96853.1 - 0.0016 18.7 13.6 0.0016 18.7 13.6 12.1 11 1 1 12 12 8 3 EGF-like domain Plasmod_Pvs28 PF06247.11 KFO96853.1 - 0.012 15.8 2.6 0.012 15.8 2.6 9.1 7 2 1 8 8 5 0 Pvs28 EGF domain DUF3734 PF12536.8 KFO96853.1 - 0.18 12.1 0.0 0.43 10.9 0.0 1.5 1 0 0 1 1 1 0 Patatin phospholipase SNF PF00209.18 KFO96854.1 - 1e-122 410.5 17.3 1.2e-122 410.3 17.3 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family PrmA PF06325.13 KFO96855.1 - 4.8e-11 42.6 0.0 8.5e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KFO96855.1 - 3.7e-10 40.4 0.2 1.3e-09 38.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFO96855.1 - 7e-09 35.7 0.0 2.1e-08 34.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFO96855.1 - 2.2e-08 34.6 0.0 1.2e-07 32.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 KFO96855.1 - 2.3e-08 33.3 0.0 3.1e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 KFO96855.1 - 2.5e-07 30.7 0.0 3.7e-06 26.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KFO96855.1 - 5e-06 26.2 0.1 1e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KFO96855.1 - 0.00059 20.5 0.0 0.0017 19.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KFO96855.1 - 0.00074 19.0 0.1 0.0014 18.1 0.1 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB zf-C2H2_2 PF12756.7 KFO96855.1 - 0.0013 19.0 0.5 0.0041 17.4 0.5 1.9 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) FtsJ PF01728.19 KFO96855.1 - 0.002 18.3 0.6 0.021 15.0 0.1 2.3 1 1 1 3 3 3 1 FtsJ-like methyltransferase Met_10 PF02475.16 KFO96855.1 - 0.002 17.9 0.4 0.0045 16.7 0.1 1.7 2 0 0 2 2 1 1 Met-10+ like-protein Methyltransf_18 PF12847.7 KFO96855.1 - 0.0025 17.8 0.1 0.0066 16.4 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KFO96855.1 - 0.0082 15.6 0.1 0.016 14.6 0.1 1.5 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 KFO96855.1 - 0.0086 15.8 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ATP-synt_B PF00430.18 KFO96855.1 - 0.015 15.4 4.1 0.024 14.7 4.1 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) PRMT5_C PF17286.2 KFO96855.1 - 0.021 14.7 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 PRMT5 oligomerisation domain CMAS PF02353.20 KFO96855.1 - 0.058 12.7 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 KFO96855.1 - 0.062 13.0 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Lysine methyltransferase PRMT5 PF05185.16 KFO96855.1 - 0.095 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Cons_hypoth95 PF03602.15 KFO96855.1 - 0.1 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 zf-C2H2_4 PF13894.6 KFO96855.1 - 1.4 9.9 6.5 1.2 10.2 2.5 3.0 4 0 0 4 4 2 0 C2H2-type zinc finger Homeodomain PF00046.29 KFO96856.1 - 2.6e-21 75.2 3.7 4.4e-21 74.5 3.7 1.3 1 0 0 1 1 1 1 Homeodomain DUF2986 PF11661.8 KFO96856.1 - 0.0087 16.6 1.4 0.0087 16.6 1.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2986) Homeobox_KN PF05920.11 KFO96856.1 - 0.0096 15.8 0.1 0.019 14.9 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 KFO96856.1 - 0.086 12.3 0.2 0.18 11.3 0.2 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez YdaS_antitoxin PF15943.5 KFO96856.1 - 0.089 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT E2F_TDP PF02319.20 KFO96857.1 - 1.8e-42 143.3 0.5 1.3e-20 73.2 0.0 2.7 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 KFO96857.1 - 0.0002 21.2 0.2 0.00066 19.5 0.1 1.9 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.12 KFO96857.1 - 0.021 15.0 0.3 16 5.7 0.0 3.2 3 0 0 3 3 3 0 B-block binding subunit of TFIIIC UPF0122 PF04297.14 KFO96857.1 - 0.083 13.1 0.4 0.24 11.6 0.4 1.8 1 1 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like LIM PF00412.22 KFO96858.1 - 1.9e-23 82.4 21.5 2.5e-16 59.6 4.2 2.5 2 1 0 2 2 2 2 LIM domain zf-ACC PF17848.1 KFO96858.1 - 0.014 15.4 8.8 0.14 12.2 0.4 3.4 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain DUF3718 PF12514.8 KFO96858.1 - 0.051 13.7 0.7 0.1 12.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3718) zf_UBZ PF18439.1 KFO96858.1 - 0.077 12.6 8.8 0.64 9.7 0.1 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_7 PF15269.6 KFO96858.1 - 0.32 11.1 4.9 7.4 6.8 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger Zn_ribbon_2 PF12674.7 KFO96858.1 - 0.45 11.2 12.2 0.4 11.4 1.4 2.7 2 1 0 2 2 2 0 Putative zinc ribbon domain zf-TFIIB PF13453.6 KFO96858.1 - 1 8.8 0.0 1 8.8 0.0 3.4 4 0 0 4 4 4 0 Transcription factor zinc-finger DUF2688 PF10892.8 KFO96858.1 - 2.1 7.9 6.7 3.1 7.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2688) ERG4_ERG24 PF01222.17 KFO96859.1 - 9.4e-93 311.3 28.9 1.2e-92 311.0 28.9 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 KFO96859.1 - 0.031 14.7 2.5 0.037 14.5 0.1 2.4 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Orf78 PF06024.12 KFO96859.1 - 0.087 13.1 0.0 0.3 11.4 0.0 1.9 1 0 0 1 1 1 0 Orf78 (ac78) DUF1295 PF06966.12 KFO96859.1 - 0.55 9.7 9.4 0.024 14.2 3.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1295) CN_hydrolase PF00795.22 KFO96860.1 - 1.3e-44 152.5 0.0 2e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KFO96860.1 - 6.3e-28 97.5 0.0 1.4e-27 96.4 0.0 1.6 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 KFO96860.1 - 0.048 13.3 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase TSC22 PF01166.18 KFO96862.1 - 1.5e-29 102.0 4.4 1.8e-29 101.8 4.4 1.1 1 0 0 1 1 1 1 TSC-22/dip/bun family YabA PF06156.13 KFO96862.1 - 0.00019 22.0 3.2 0.00023 21.7 3.2 1.1 1 0 0 1 1 1 1 Initiation control protein YabA K-box PF01486.17 KFO96862.1 - 0.0005 20.2 1.6 0.00064 19.8 1.6 1.1 1 0 0 1 1 1 1 K-box region DivIC PF04977.15 KFO96862.1 - 0.0033 17.2 4.5 0.0034 17.1 4.1 1.3 1 1 0 1 1 1 1 Septum formation initiator ZapB PF06005.12 KFO96862.1 - 0.02 15.3 8.0 0.029 14.8 8.0 1.5 1 1 0 1 1 1 0 Cell division protein ZapB Fzo_mitofusin PF04799.13 KFO96862.1 - 0.025 14.2 1.8 0.026 14.1 1.8 1.0 1 0 0 1 1 1 0 fzo-like conserved region bZIP_2 PF07716.15 KFO96862.1 - 0.043 13.9 5.2 0.074 13.1 5.2 1.3 1 0 0 1 1 1 0 Basic region leucine zipper NYD-SP28_assoc PF14775.6 KFO96862.1 - 0.055 13.6 1.4 0.087 12.9 1.4 1.3 1 0 0 1 1 1 0 Sperm tail C-terminal domain bZIP_1 PF00170.21 KFO96862.1 - 0.27 11.3 4.9 0.35 11.0 4.6 1.4 1 1 0 1 1 1 0 bZIP transcription factor Cu-oxidase_4 PF02578.15 KFO96863.1 - 4e-57 193.5 0.0 5.9e-57 192.9 0.0 1.2 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase UPF0058 PF01893.16 KFO96863.1 - 0.088 13.1 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0058 TMF_TATA_bd PF12325.8 KFO96864.1 - 0.084 13.1 35.9 1.1 9.5 9.9 4.1 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding TolA_bind_tri PF16331.5 KFO96864.1 - 0.11 12.6 26.4 0.37 10.9 0.9 5.9 2 2 2 4 4 4 0 TolA binding protein trimerisation zf-C4H2 PF10146.9 KFO96864.1 - 0.27 11.5 30.7 0.11 12.8 9.8 2.9 1 1 1 2 2 2 0 Zinc finger-containing protein Spc7 PF08317.11 KFO96864.1 - 0.43 9.4 37.8 0.34 9.8 10.6 2.8 1 1 1 2 2 2 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KFO96864.1 - 1.1 9.3 41.4 4.3 7.4 5.7 3.9 1 1 4 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LPP PF04728.13 KFO96864.1 - 1.3 9.4 8.6 15 6.0 0.2 4.8 4 2 2 6 6 6 0 Lipoprotein leucine-zipper Cep57_MT_bd PF06657.13 KFO96864.1 - 1.9 9.0 28.8 0.24 11.9 4.3 4.9 1 1 4 5 5 5 0 Centrosome microtubule-binding domain of Cep57 Shugoshin_N PF07558.11 KFO96864.1 - 2.1 8.3 12.1 4.4 7.3 0.3 4.4 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region Cdh1_DBD_1 PF18196.1 KFO96864.1 - 2.3 8.6 21.6 0.47 10.8 3.9 3.7 2 1 1 3 3 3 0 Chromodomain helicase DNA-binding domain 1 Fib_alpha PF08702.10 KFO96864.1 - 2.3 8.4 24.4 2.7 8.2 2.8 3.1 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family GIT_CC PF16559.5 KFO96864.1 - 2.5 8.0 19.2 0.52 10.2 0.4 4.5 4 1 1 5 5 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4407 PF14362.6 KFO96864.1 - 2.6 7.3 20.3 6.5e+02 -0.6 20.3 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SHE3 PF17078.5 KFO96864.1 - 2.7 7.7 25.2 0.14 11.9 2.7 3.2 2 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 HrpB7 PF09486.10 KFO96864.1 - 2.8 8.3 16.0 2.3 8.6 1.7 3.0 2 2 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF1192 PF06698.11 KFO96864.1 - 2.9 8.0 18.3 0.27 11.3 0.9 4.3 4 2 0 4 4 3 0 Protein of unknown function (DUF1192) APG6_N PF17675.1 KFO96864.1 - 3.3 8.2 42.9 0.29 11.7 11.2 3.8 1 1 2 3 3 3 0 Apg6 coiled-coil region DUF1664 PF07889.12 KFO96864.1 - 3.4 7.7 22.2 1.6 8.7 6.1 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) MAD PF05557.13 KFO96864.1 - 4.5 5.5 36.6 0.69 8.2 23.6 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein FlaC_arch PF05377.11 KFO96864.1 - 4.6 7.7 13.2 7.7 7.0 0.3 5.1 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) ADIP PF11559.8 KFO96864.1 - 5.2 7.1 35.9 1.6 8.8 6.4 3.8 1 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 KFO96864.1 - 5.3 7.2 33.6 4.6 7.4 11.2 3.5 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 KFO96864.1 - 5.7 7.0 37.3 1.6 8.8 0.9 4.4 2 2 2 4 4 4 0 TATA element modulatory factor 1 DNA binding FAM76 PF16046.5 KFO96864.1 - 6.3 6.1 27.1 2.6 7.3 16.2 2.3 1 1 0 2 2 2 0 FAM76 protein DUF724 PF05266.14 KFO96864.1 - 8 6.2 33.0 0.38 10.6 5.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF724) DUF4094 PF13334.6 KFO96864.1 - 9.3 6.7 17.5 0.45 11.0 1.3 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) Tiam_CC_Ex PF18385.1 KFO96864.1 - 9.5 6.7 7.5 0.69 10.3 0.3 2.6 2 1 1 3 3 3 0 T-lymphoma invasion and metastasis CC-Ex domain RRM_1 PF00076.22 KFO96865.1 - 4.1e-09 36.1 0.0 1e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFO96865.1 - 0.0026 17.8 0.1 0.059 13.5 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif bZIP_1 PF00170.21 KFO96865.1 - 0.08 13.0 0.5 0.08 13.0 0.5 4.1 4 0 0 4 4 4 0 bZIP transcription factor Phage_holin_7_1 PF16081.5 KFO96865.1 - 0.42 10.8 1.2 0.83 9.8 0.0 1.9 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family SesA PF17107.5 KFO96865.1 - 1.6 8.9 10.9 6 7.1 2.7 2.8 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Cob_adeno_trans PF01923.18 KFO96865.1 - 4.1 7.5 8.1 13 5.9 2.6 2.4 2 0 0 2 2 2 0 Cobalamin adenosyltransferase DnaJ PF00226.31 KFO96866.1 - 9.7e-06 25.6 0.0 1.6e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain PVL_ORF50 PF07768.11 KFO96867.1 - 0.3 11.4 23.7 0.76 10.1 9.6 2.4 2 0 0 2 2 2 0 PVL ORF-50-like family TFIIA PF03153.13 KFO96867.1 - 7 6.5 21.6 9.6 6.1 21.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit VWC PF00093.18 KFO96868.1 - 2.7e-09 37.2 53.2 7.9e-06 26.1 17.1 3.2 3 0 0 3 3 3 3 von Willebrand factor type C domain Pacifastin_I PF05375.13 KFO96868.1 - 0.00081 19.1 4.0 0.00081 19.1 4.0 3.9 3 0 0 3 3 3 2 Pacifastin inhibitor (LCMII) zf-CCCH_2 PF14608.6 KFO96868.1 - 0.66 10.5 0.1 0.66 10.5 0.1 4.9 5 0 0 5 5 5 0 RNA-binding, Nab2-type zinc finger Ank_2 PF12796.7 KFO96869.1 - 4.9e-23 81.5 0.7 8.4e-19 68.0 0.3 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFO96869.1 - 1.1e-19 69.9 2.1 1.8e-05 25.0 0.0 3.8 4 0 0 4 4 3 3 Ankyrin repeat Ank_5 PF13857.6 KFO96869.1 - 1.7e-19 69.6 1.1 7.1e-10 39.0 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFO96869.1 - 3.8e-18 65.6 0.2 1.3e-11 44.7 0.0 2.7 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFO96869.1 - 6.3e-17 60.0 0.1 1.3e-05 25.2 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat zf-RING_6 PF14835.6 KFO96869.1 - 2.2e-13 49.8 1.1 2.2e-13 49.8 1.1 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein BRCT_2 PF16589.5 KFO96869.1 - 2.2e-09 37.6 0.1 5.2e-06 26.8 0.0 2.8 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KFO96869.1 - 4e-09 36.7 0.1 0.00019 21.7 0.0 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KFO96869.1 - 0.0047 16.8 0.1 0.013 15.3 0.1 1.8 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain NIBRIN_BRCT_II PF16508.5 KFO96869.1 - 0.011 16.0 0.0 0.033 14.5 0.0 1.8 1 0 0 1 1 1 0 Second BRCT domain on Nijmegen syndrome breakage protein PTCB-BRCT PF12738.7 KFO96869.1 - 0.056 13.4 0.1 0.31 11.0 0.1 2.2 2 0 0 2 2 2 0 twin BRCT domain ABC_tran PF00005.27 KFO96870.1 - 3.4e-53 179.8 2.4 8.6e-29 100.8 0.0 3.9 3 1 1 4 4 4 2 ABC transporter ABC2_membrane_3 PF12698.7 KFO96870.1 - 9.2e-48 163.1 53.2 5e-29 101.5 15.9 3.3 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KFO96870.1 - 3e-26 92.9 0.1 7.1e-09 35.9 0.0 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 KFO96870.1 - 0.0031 18.2 0.0 0.013 16.2 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) IstB_IS21 PF01695.17 KFO96870.1 - 0.0037 17.0 0.5 0.68 9.6 0.0 3.3 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_23 PF13476.6 KFO96870.1 - 0.0046 17.5 16.5 0.017 15.6 0.2 4.0 4 0 0 4 4 4 2 AAA domain RsgA_GTPase PF03193.16 KFO96870.1 - 0.007 16.3 0.4 3.1 7.7 0.1 2.9 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KFO96870.1 - 0.072 13.5 0.1 7.9 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 KFO96870.1 - 0.081 13.0 0.5 3.9 7.6 0.0 3.2 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_30 PF13604.6 KFO96870.1 - 0.087 12.5 0.0 3.6 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KFO96870.1 - 0.097 12.4 3.6 1.3 8.9 0.4 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRP54 PF00448.22 KFO96870.1 - 1.5 8.4 6.8 1.8 8.1 0.2 2.7 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AICARFT_IMPCHas PF01808.18 KFO96871.1 - 2.2e-94 316.2 0.0 2.9e-94 315.8 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KFO96871.1 - 3.1e-24 85.0 0.0 6.4e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain Ribosomal_L12_N PF16320.5 KFO96871.1 - 0.012 15.3 0.4 0.036 13.8 0.4 1.8 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain DUF730 PF05325.11 KFO96872.1 - 0.2 11.7 0.1 0.24 11.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF730) fn3 PF00041.21 KFO96873.1 - 2.3e-262 848.3 76.5 1.7e-20 73.1 0.8 17.4 17 0 0 17 17 17 17 Fibronectin type III domain fn1 PF00039.18 KFO96873.1 - 7.2e-149 483.7 168.5 4.9e-15 55.4 5.2 12.8 12 0 0 12 12 12 12 Fibronectin type I domain fn2 PF00040.19 KFO96873.1 - 5.3e-31 106.6 29.5 1.4e-16 60.4 7.2 3.9 3 0 0 3 3 2 2 Fibronectin type II domain Pur_ac_phosph_N PF16656.5 KFO96873.1 - 5.6e-31 107.0 59.2 0.00042 20.8 0.0 19.6 16 7 0 16 16 16 9 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 KFO96873.1 - 2.1e-24 85.7 16.3 0.19 12.1 0.0 13.8 13 1 1 14 14 14 6 Uncharacterised conserved protein (DUF2369) Interfer-bind PF09294.10 KFO96873.1 - 3.1e-18 66.0 0.1 0.41 11.0 0.0 12.6 13 0 0 13 13 12 1 Interferon-alpha/beta receptor, fibronectin type III DUF4959 PF16323.5 KFO96873.1 - 1.1e-10 41.7 3.7 2.2 8.6 0.0 8.0 9 0 0 9 9 9 2 Domain of unknown function (DUF4959) DUF4912 PF16258.5 KFO96873.1 - 8e-07 29.3 0.0 1.5 9.0 0.0 6.7 8 0 0 8 8 7 1 Domain of unknown function (DUF4912) fn3_2 PF16893.5 KFO96873.1 - 4.3e-05 23.6 3.4 0.74 10.0 0.0 7.1 8 0 0 8 8 8 1 Fibronectin type III domain TILa PF12714.7 KFO96873.1 - 0.0013 18.7 1.6 0.0013 18.7 1.6 11.4 5 3 7 12 12 12 1 TILa domain DUF1410 PF07198.11 KFO96873.1 - 0.0023 18.4 4.1 38 4.9 0.0 7.1 8 0 0 8 8 7 0 Protein of unknown function (DUF1410) MG4 PF17789.1 KFO96873.1 - 0.013 15.6 0.2 0.095 12.9 0.2 2.5 1 0 0 1 1 1 0 Macroglobulin domain MG4 Glyco_hydro_66 PF13199.6 KFO96873.1 - 0.037 12.7 3.9 32 3.0 0.1 5.3 4 2 2 6 6 6 0 Glycosyl hydrolase family 66 DUF2012 PF09430.10 KFO96873.1 - 0.074 13.2 0.1 27 4.9 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2012) Big_10 PF17964.1 KFO96873.1 - 1.1 9.2 6.7 5.7 6.9 0.0 4.7 5 0 0 5 5 4 0 Bacterial Ig domain Arylsulfotran_N PF17425.2 KFO96873.1 - 4.9 7.2 22.8 0.8 9.8 0.4 7.1 8 0 0 8 8 8 0 Arylsulfotransferase Ig-like domain MREG PF15812.5 KFO96874.1 - 7e-70 234.1 5.3 8e-70 233.9 5.3 1.0 1 0 0 1 1 1 1 Melanoregulin AIP3 PF03915.13 KFO96874.1 - 0.0085 15.2 0.5 0.01 14.9 0.5 1.0 1 0 0 1 1 1 1 Actin interacting protein 3 Lipoprotein_6 PF01441.19 KFO96874.1 - 0.099 12.6 0.1 0.19 11.7 0.0 1.4 1 1 0 1 1 1 0 Lipoprotein S_100 PF01023.19 KFO96875.1 - 8e-21 73.5 0.7 1.2e-20 72.9 0.7 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_7 PF13499.6 KFO96875.1 - 5.1e-05 23.6 1.6 8.5e-05 22.9 1.6 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFO96875.1 - 7.4e-05 22.0 2.1 0.00012 21.4 0.3 2.3 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 KFO96875.1 - 0.0024 17.7 0.2 0.27 11.3 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 KFO96875.1 - 0.026 14.5 0.6 0.03 14.3 0.6 1.3 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand AMP-binding PF00501.28 KFO96876.1 - 2.5e-93 313.0 0.3 9.1e-66 222.2 0.1 2.3 2 0 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.11 KFO96876.1 - 4.5e-11 43.5 2.2 9.1e-11 42.6 2.2 1.5 1 0 0 1 1 1 1 DMAP1-binding Domain AMP-binding_C PF13193.6 KFO96876.1 - 0.24 12.4 1.2 1 10.4 1.2 2.1 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain MAGE_N PF12440.8 KFO96876.1 - 8.3 7.2 12.6 8.2 7.2 1.7 2.7 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal PACT_coil_coil PF10495.9 KFO96878.1 - 3e-28 98.2 0.1 4.8e-28 97.6 0.1 1.3 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein ENT PF03735.14 KFO96879.1 - 0.24 11.5 11.3 2.4 8.3 1.8 2.8 2 1 0 2 2 2 0 ENT domain PKK PF12474.8 KFO96879.1 - 3.1 7.9 30.6 0.12 12.5 22.2 2.0 1 1 1 2 2 2 0 Polo kinase kinase Leucyl-specific PF14795.6 KFO96879.1 - 3.1 7.9 7.0 11 6.2 0.3 3.1 1 1 1 3 3 3 0 Leucine-tRNA synthetase-specific domain DUF4587 PF15248.6 KFO96880.1 - 1.5e-32 112.2 10.6 1.5e-32 112.2 10.6 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF4587) APH PF01636.23 KFO96880.1 - 1.1 9.1 5.6 0.38 10.6 0.5 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family FAD_binding_3 PF01494.19 KFO96881.1 - 1.9e-21 76.7 0.0 2.9e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFO96881.1 - 5.1e-07 29.6 0.0 0.00048 19.8 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFO96881.1 - 5.7e-06 26.5 0.2 1.6e-05 25.0 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 KFO96881.1 - 0.00015 20.9 0.1 0.12 11.4 0.0 2.5 2 1 1 3 3 3 2 Squalene epoxidase 3HCDH_N PF02737.18 KFO96881.1 - 0.0024 17.8 0.1 0.004 17.1 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KFO96881.1 - 0.0046 17.5 0.1 0.009 16.5 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFO96881.1 - 0.0063 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KFO96881.1 - 0.045 14.2 0.0 0.084 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KFO96881.1 - 0.19 11.3 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Integrin_beta PF00362.18 KFO96882.1 - 3.9e-116 387.0 0.0 5.7e-116 386.5 0.0 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_b_cyt PF08725.11 KFO96882.1 - 5.9e-20 70.7 0.9 1.3e-19 69.6 0.9 1.6 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.12 KFO96882.1 - 4.2e-18 65.6 11.5 4.2e-18 65.6 11.5 4.8 3 1 1 5 5 5 1 Integrin beta tail domain PSI_integrin PF17205.3 KFO96882.1 - 2e-15 56.2 6.4 2e-15 56.2 6.4 4.2 4 0 0 4 4 4 1 Integrin plexin domain I-EGF_1 PF18372.1 KFO96882.1 - 1.6e-08 34.5 14.4 1.6e-08 34.5 14.4 6.8 8 0 0 8 8 8 2 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 KFO96882.1 - 1e-05 25.8 100.6 0.0056 17.0 11.1 7.4 6 1 1 7 7 7 4 EGF-like domain SLX9 PF15341.6 KFO96883.1 - 2.7e-15 56.9 6.9 3.3e-15 56.7 6.9 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 IFT46_B_C PF12317.8 KFO96883.1 - 0.016 14.9 0.2 0.019 14.7 0.2 1.1 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal A_deamin PF02137.18 KFO96884.1 - 2.9e-116 388.5 0.0 3.8e-116 388.1 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.26 KFO96884.1 - 1.7e-26 92.7 0.2 1.3e-12 48.2 0.1 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KFO96884.1 - 0.029 14.6 2.1 1.4 9.2 0.2 3.2 2 2 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 Endostatin PF06482.11 KFO96885.1 - 6.1e-111 370.9 0.0 8.3e-111 370.4 0.0 1.1 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin Collagen PF01391.18 KFO96885.1 - 1.4e-62 207.3 358.8 3.7e-09 36.2 16.2 16.3 8 4 6 14 14 14 13 Collagen triple helix repeat (20 copies) Laminin_G_3 PF13385.6 KFO96885.1 - 0.00068 19.8 0.0 0.0012 19.1 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Folate_carrier PF01770.18 KFO96886.1 - 3.5e-168 559.6 15.3 4e-168 559.4 15.3 1.0 1 0 0 1 1 1 1 Reduced folate carrier MFS_1 PF07690.16 KFO96886.1 - 1.6e-11 43.7 28.8 1.9e-11 43.5 28.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily KH_1 PF00013.29 KFO96887.1 - 6.3e-45 150.8 9.0 3.5e-19 68.4 0.4 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KFO96887.1 - 2.1e-11 43.5 0.1 3.9e-06 26.6 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 KFO96887.1 - 5.3e-05 23.2 1.1 0.27 11.3 0.2 2.4 2 0 0 2 2 2 2 NusA-like KH domain MOEP19 PF16005.5 KFO96887.1 - 0.00036 20.5 0.0 0.019 14.9 0.0 2.4 2 0 0 2 2 2 1 KH-like RNA-binding domain KH_4 PF13083.6 KFO96887.1 - 0.00057 19.7 0.1 0.88 9.5 0.0 2.5 2 0 0 2 2 2 2 KH domain DUF370 PF04025.12 KFO96887.1 - 0.11 12.7 0.3 0.67 10.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF370) VWA PF00092.28 KFO96888.1 - 1.8e-85 285.6 2.1 1.1e-28 100.7 0.0 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain Collagen PF01391.18 KFO96888.1 - 3e-52 174.2 204.7 5.7e-10 38.8 21.3 7.2 1 1 5 7 7 7 7 Collagen triple helix repeat (20 copies) VWA_2 PF13519.6 KFO96888.1 - 8.5e-41 138.9 4.9 1.8e-18 67.2 0.1 3.7 4 0 0 4 4 4 3 von Willebrand factor type A domain VWA_3 PF13768.6 KFO96888.1 - 4.4e-08 33.2 0.1 1.1e-05 25.4 0.1 3.3 3 1 0 3 3 3 1 von Willebrand factor type A domain DUF1194 PF06707.11 KFO96888.1 - 7.2e-06 25.4 1.1 0.025 13.8 0.8 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF1194) VWA_CoxE PF05762.14 KFO96888.1 - 0.0035 16.7 0.3 4 6.8 0.0 3.3 4 0 0 4 4 4 2 VWA domain containing CoxE-like protein DUF5507 PF17612.2 KFO96888.1 - 0.15 11.8 0.1 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5507) VWA PF00092.28 KFO96889.1 - 1.3e-87 292.5 3.3 3.7e-30 105.4 0.5 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain Collagen PF01391.18 KFO96889.1 - 1e-51 172.5 203.9 1.2e-09 37.7 33.7 7.2 1 1 5 6 6 6 5 Collagen triple helix repeat (20 copies) VWA_2 PF13519.6 KFO96889.1 - 9.9e-37 125.9 0.7 4.7e-13 49.7 0.0 3.4 3 0 0 3 3 3 3 von Willebrand factor type A domain FTCD_N PF07837.12 KFO96890.1 - 4.6e-72 241.5 0.0 7.7e-72 240.8 0.0 1.4 1 0 0 1 1 1 1 Formiminotransferase domain, N-terminal subdomain FTCD PF02971.14 KFO96890.1 - 4.7e-69 231.0 0.0 1.1e-68 229.8 0.0 1.6 2 0 0 2 2 2 1 Formiminotransferase domain FTCD_C PF04961.12 KFO96890.1 - 1.7e-66 223.4 0.3 2.8e-66 222.8 0.3 1.3 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase Keratin PF02422.16 KFO96891.1 - 8.7e-32 108.7 14.1 9.2e-32 108.6 14.1 1.0 1 0 0 1 1 1 1 Keratin MCM3AP_GANP PF16769.5 KFO96892.1 - 0 1110.1 8.2 0 1110.1 8.2 1.5 2 0 0 2 2 2 1 MCM3AP domain of GANP SAC3_GANP PF03399.16 KFO96892.1 - 2.8e-117 391.3 4.1 2.8e-117 391.3 4.1 1.9 2 0 0 2 2 2 1 SAC3/GANP family CID_GANP PF16766.5 KFO96892.1 - 1.7e-28 98.6 11.1 1.9e-28 98.4 4.9 3.1 2 0 0 2 2 2 1 Binding region of GANP to ENY2 CSN8_PSD8_EIF3K PF10075.9 KFO96892.1 - 4.5e-06 26.7 0.0 1.2e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family UPF0158 PF03682.13 KFO96892.1 - 0.025 14.6 1.7 0.073 13.0 1.0 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0158) DUF3067 PF11267.8 KFO96892.1 - 0.095 13.3 0.0 0.6 10.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3067) CNOT11 PF10155.9 KFO96892.1 - 0.17 12.1 2.1 0.51 10.5 2.1 1.8 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 11 RRM_1 PF00076.22 KFO96892.1 - 0.17 11.7 0.0 0.44 10.4 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UPF0054 PF02130.17 KFO96893.1 - 5.1e-24 84.5 0.0 5.6e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 O-FucT PF10250.9 KFO96894.1 - 7.2e-70 236.3 0.0 8.4e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase PAS_3 PF08447.12 KFO96895.1 - 1.4e-17 63.7 0.3 7.4e-12 45.4 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KFO96895.1 - 2.8e-12 46.8 0.1 3.4e-10 40.1 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KFO96895.1 - 6.8e-11 42.2 0.0 2.2e-08 34.1 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KFO96895.1 - 0.00043 20.5 0.0 0.076 13.3 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KFO96895.1 - 0.084 13.1 0.1 4.4 7.6 0.0 2.5 2 0 0 2 2 2 0 PAS fold DUF4413 PF14372.6 KFO96898.1 - 0.06 13.7 0.1 0.19 12.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) SWIM PF04434.17 KFO96898.1 - 0.12 12.1 3.4 0.3 10.8 3.4 1.7 1 0 0 1 1 1 0 SWIM zinc finger RVT_1 PF00078.27 KFO96899.1 - 4.3e-12 46.0 0.1 9.6e-12 44.9 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFO96900.1 - 7e-24 84.3 0.4 1.3e-23 83.4 0.4 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_Zn PF02022.19 KFO96900.1 - 1.3e-10 41.1 0.8 3.6e-10 39.6 0.8 1.8 1 0 0 1 1 1 1 Integrase Zinc binding domain RNase_H PF00075.24 KFO96900.1 - 2.1e-07 31.2 0.0 4.6e-07 30.1 0.0 1.6 2 0 0 2 2 2 1 RNase H DDE_Tnp_IS240 PF13610.6 KFO96900.1 - 0.00073 19.8 0.0 0.0011 19.2 0.0 1.2 1 0 0 1 1 1 1 DDE domain RVT_1 PF00078.27 KFO96902.1 - 1.3e-13 51.0 0.0 2e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFO96902.1 - 1.5e-06 28.2 0.0 2.9e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Motilin_assoc PF04643.12 KFO96902.1 - 0.063 13.1 0.1 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 Motilin/ghrelin-associated peptide 7tm_4 PF13853.6 KFO96903.1 - 3.5e-36 125.4 9.6 4.2e-36 125.1 9.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO96903.1 - 7.6e-28 97.6 9.1 1.1e-27 97.1 9.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) YccF PF03733.13 KFO96903.1 - 0.079 13.7 0.9 0.079 13.7 0.9 4.0 3 2 0 3 3 3 0 Inner membrane component domain 7TM_GPCR_Srsx PF10320.9 KFO96903.1 - 0.24 10.8 14.9 0.38 10.1 14.9 1.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx HALZ PF02183.18 KFO96904.1 - 0.014 15.6 2.2 2.4 8.4 0.6 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF5401 PF17380.2 KFO96904.1 - 0.027 12.6 4.8 0.033 12.3 4.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Rootletin PF15035.6 KFO96904.1 - 0.033 14.2 5.7 0.73 9.8 3.3 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion CorA PF01544.18 KFO96904.1 - 0.043 13.1 1.0 0.056 12.7 1.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Cep57_CLD_2 PF14197.6 KFO96904.1 - 0.044 13.9 8.9 2.4 8.3 3.2 3.0 2 2 0 2 2 2 0 Centrosome localisation domain of PPC89 betaPIX_CC PF16523.5 KFO96904.1 - 0.047 13.5 1.4 0.067 13.0 0.3 1.8 1 1 1 2 2 2 0 betaPIX coiled coil PI_PP_I PF18363.1 KFO96904.1 - 0.048 13.8 1.6 0.38 11.0 0.6 2.2 1 1 0 2 2 2 0 Phosphoinositide phosphatase insertion domain OmpH PF03938.14 KFO96904.1 - 0.062 13.6 3.8 0.093 13.1 3.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PRD PF00874.20 KFO96904.1 - 0.063 13.6 2.9 5.6 7.3 0.2 2.2 2 0 0 2 2 2 0 PRD domain DUF5595 PF18077.1 KFO96904.1 - 0.11 12.6 4.6 2.3 8.4 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5595) YabA PF06156.13 KFO96904.1 - 0.12 13.0 6.1 0.34 11.6 2.0 2.3 1 1 0 2 2 2 0 Initiation control protein YabA DUF724 PF05266.14 KFO96904.1 - 0.22 11.3 5.4 0.31 10.8 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FapA PF03961.13 KFO96904.1 - 0.57 8.7 4.3 0.72 8.4 4.3 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Uso1_p115_C PF04871.13 KFO96904.1 - 0.8 10.1 7.4 1.9 8.8 7.3 1.7 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DivIVA PF05103.13 KFO96904.1 - 0.87 9.7 8.6 5.8 7.0 8.5 2.0 1 1 0 1 1 1 0 DivIVA protein DUF5517 PF17639.2 KFO96904.1 - 0.93 9.8 5.0 7.2 7.0 0.5 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5517) SseC PF04888.12 KFO96904.1 - 1.2 8.7 5.1 13 5.2 0.1 2.1 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family zf-H2C2_2 PF13465.6 KFO96905.1 - 6.7e-16 57.9 34.3 8.9e-08 32.2 2.7 7.4 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFO96905.1 - 9.1e-15 54.2 46.1 7.8e-05 22.9 1.3 7.0 7 0 0 7 7 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO96905.1 - 2.2e-11 43.6 41.4 0.00087 19.9 1.1 6.9 6 0 0 6 6 6 4 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFO96905.1 - 5.3e-05 22.9 6.3 0.00048 19.8 1.3 5.3 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KFO96905.1 - 0.0024 18.2 2.5 0.0024 18.2 2.5 5.3 4 2 3 7 7 6 2 C2H2 type zinc-finger (2 copies) zf-MYND PF01753.18 KFO96905.1 - 0.011 15.8 7.1 0.23 11.6 0.0 3.6 3 1 0 3 3 3 0 MYND finger GAGA PF09237.11 KFO96905.1 - 0.02 14.7 3.1 0.17 11.7 0.1 3.0 2 1 1 3 3 3 0 GAGA factor zf-C2H2_11 PF16622.5 KFO96905.1 - 0.11 12.2 0.3 0.11 12.2 0.3 4.3 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-met PF12874.7 KFO96905.1 - 0.29 11.6 0.2 0.29 11.6 0.2 6.1 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFO96905.1 - 0.89 9.9 0.0 0.89 9.9 0.0 5.8 7 0 0 7 7 6 0 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KFO96905.1 - 1.1 9.8 23.4 0.89 10.1 1.2 5.8 5 1 1 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_8 PF15909.5 KFO96905.1 - 1.1 9.6 13.5 0.24 11.7 2.6 3.5 3 1 0 3 3 3 0 C2H2-type zinc ribbon DUF3268 PF11672.8 KFO96905.1 - 1.4 9.3 8.2 2 8.8 0.3 3.1 3 0 0 3 3 3 0 zinc-finger-containing domain GATA PF00320.27 KFO96905.1 - 3.3 7.4 10.7 10 5.9 0.2 4.1 3 1 0 3 3 3 0 GATA zinc finger zinc_ribbon_15 PF17032.5 KFO96905.1 - 4.4 8.1 14.0 5.7 7.8 0.5 3.9 4 0 0 4 4 4 0 zinc-ribbon family zf-TRAF PF02176.18 KFO96905.1 - 6.8 7.5 16.2 0.7 10.6 4.2 3.4 3 0 0 3 3 3 0 TRAF-type zinc finger Pkinase_Tyr PF07714.17 KFO96906.1 - 1.3e-91 306.5 0.0 2.4e-91 305.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.24 KFO96906.1 - 1.6e-58 195.7 4.0 1.1e-29 102.8 0.2 2.4 2 0 0 2 2 2 2 Receptor L domain GF_recep_IV PF14843.6 KFO96906.1 - 1.3e-52 177.1 80.8 1.1e-46 157.9 28.0 4.0 2 1 1 3 3 3 3 Growth factor receptor domain IV Pkinase PF00069.25 KFO96906.1 - 1.4e-39 136.0 0.0 2.2e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.20 KFO96906.1 - 2e-35 121.9 86.7 2.7e-28 98.7 41.8 4.4 2 1 2 4 4 4 3 Furin-like cysteine rich region Haspin_kinase PF12330.8 KFO96906.1 - 0.0028 16.7 0.0 0.0047 15.9 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFO96906.1 - 0.013 15.4 0.1 0.022 14.7 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KFO96906.1 - 0.022 14.1 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF3951 PF13131.6 KFO96906.1 - 0.16 12.2 1.7 0.36 11.1 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) CPSase_L_D2 PF02786.17 KFO96907.1 - 7.8e-113 375.2 0.6 5e-81 271.2 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 KFO96907.1 - 1.3e-44 151.1 0.0 3.4e-44 149.8 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.19 KFO96907.1 - 7.4e-37 126.4 0.1 1.6e-36 125.4 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain GATase PF00117.28 KFO96907.1 - 4.2e-35 121.2 0.0 8e-35 120.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I ATP-grasp PF02222.22 KFO96907.1 - 4.8e-18 65.3 0.3 3.3e-09 36.6 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.22 KFO96907.1 - 6.4e-18 64.7 0.0 1e-16 60.9 0.0 2.6 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 KFO96907.1 - 1.6e-13 50.7 0.5 6.7e-06 25.8 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KFO96907.1 - 1.8e-11 43.9 0.0 4.8e-05 23.1 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 KFO96907.1 - 0.00015 21.9 0.2 0.12 12.4 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain CPSase_C PF18302.1 KFO96907.1 - 0.038 14.3 0.4 0.1 13.0 0.4 1.8 1 0 0 1 1 1 0 Carbamoyl phosphate synthetase C-terminal domain ATP-grasp_5 PF13549.6 KFO96907.1 - 0.066 12.7 0.0 6.7 6.1 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain LANC_like PF05147.13 KFO96908.1 - 4.6e-105 351.1 1.4 5.7e-105 350.8 1.4 1.1 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Glyco_hydro_127 PF07944.12 KFO96908.1 - 0.022 13.3 1.2 1.1 7.6 0.4 2.3 2 1 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 C5-epim_C PF06662.13 KFO96908.1 - 0.064 12.8 5.0 1.7 8.1 0.1 3.6 3 1 1 4 4 4 0 D-glucuronyl C5-epimerase C-terminus EF-hand_1 PF00036.32 KFO96909.1 - 2.1e-11 42.5 5.0 0.009 15.5 0.1 5.0 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KFO96909.1 - 3.3e-11 42.2 0.8 0.00059 19.6 0.2 4.4 4 1 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 KFO96909.1 - 4.6e-11 43.0 0.2 6.2e-05 23.4 0.1 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFO96909.1 - 4.3e-06 26.5 1.9 0.11 12.4 0.0 3.3 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 KFO96909.1 - 0.00049 20.4 0.0 0.77 10.1 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain SapB_1 PF05184.15 KFO96909.1 - 0.036 14.1 0.0 6.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Saposin-like type B, region 1 Cas9_REC PF16592.5 KFO96909.1 - 0.054 12.2 0.1 0.06 12.1 0.1 1.2 1 0 0 1 1 1 0 REC lobe of CRISPR-associated endonuclease Cas9 Acyl-CoA_dh_1 PF00441.24 KFO96910.1 - 1.7e-42 145.2 0.2 2.4e-42 144.7 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFO96910.1 - 1.4e-30 106.3 0.0 3e-30 105.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFO96910.1 - 9.9e-26 89.8 0.0 2.4e-25 88.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFO96910.1 - 1.7e-08 34.8 0.0 2.8e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 KFO96910.1 - 0.1 13.1 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal PEHE PF15275.6 KFO96911.1 - 2.1e-22 80.1 8.2 2.1e-22 80.1 8.2 4.0 4 0 0 4 4 4 1 PEHE domain Ribul_P_3_epim PF00834.19 KFO96912.1 - 6.7e-45 152.9 0.1 7.7e-45 152.7 0.1 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family TMP-TENI PF02581.17 KFO96912.1 - 0.0017 17.7 0.0 0.0029 17.0 0.0 1.3 1 1 0 1 1 1 1 Thiamine monophosphate synthase QRPTase_C PF01729.19 KFO96912.1 - 0.0032 17.2 0.0 0.0044 16.8 0.0 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.24 KFO96912.1 - 0.0054 16.3 0.0 0.009 15.6 0.0 1.3 1 1 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family His_biosynth PF00977.21 KFO96912.1 - 0.037 13.5 0.0 0.28 10.6 0.0 1.9 1 1 1 2 2 2 0 Histidine biosynthesis protein RIX1 PF08167.12 KFO96913.1 - 0.11 12.2 1.3 1.5 8.5 0.1 2.7 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis UNC80 PF15778.5 KFO96914.1 - 1.3e-90 302.1 0.0 1.6e-90 301.7 0.0 1.1 1 0 0 1 1 1 1 Cation channel complex component UNC80 Tubulin-binding PF00418.19 KFO96915.1 - 6.8e-63 208.3 21.1 9.9e-16 57.5 2.6 5.5 5 0 0 5 5 5 5 Tau and MAP protein, tubulin-binding repeat RII_binding_1 PF10522.9 KFO96915.1 - 0.00042 20.2 2.9 0.0011 18.9 2.9 1.8 1 0 0 1 1 1 1 RII binding domain NTR PF01759.21 KFO96916.1 - 3.5e-21 75.0 3.4 5.8e-21 74.3 0.8 2.0 1 1 1 2 2 2 2 UNC-6/NTR/C345C module Nckap1 PF09735.9 KFO96917.1 - 0 1677.8 27.5 0 1677.6 27.5 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein DSPc PF00782.20 KFO96918.1 - 1.3e-31 109.1 0.0 1.5e-31 109.0 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFO96918.1 - 0.0022 17.6 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF739 PF05339.11 KFO96918.1 - 0.13 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF739) Nup35_RRM PF05172.13 KFO96919.1 - 1.4e-26 92.4 0.1 2.3e-26 91.7 0.1 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 KFO96919.1 - 1.5e-10 40.9 0.0 2.2e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif HAP1_N PF04849.13 KFO96920.1 - 4.6e-124 413.6 38.1 6.3e-124 413.2 38.1 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Milton PF12448.8 KFO96920.1 - 1.9e-30 106.3 2.3 3e-30 105.6 0.8 2.2 2 0 0 2 2 2 1 Kinesin associated protein DUF2937 PF11157.8 KFO96920.1 - 0.14 11.8 1.2 0.51 10.0 1.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Mce4_CUP1 PF11887.8 KFO96920.1 - 0.23 10.9 1.1 4.3 6.7 0.1 2.2 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative BLOC1_2 PF10046.9 KFO96920.1 - 0.72 10.2 12.4 0.23 11.8 4.7 3.0 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_Mu_Gam PF07352.12 KFO96920.1 - 2 8.3 9.1 0.4 10.6 3.4 2.6 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein Flu_NS2 PF00601.19 KFO96920.1 - 2.9 8.2 9.2 9.2 6.6 0.2 3.4 2 1 1 3 3 3 0 Influenza non-structural protein (NS2) CCDC144C PF14915.6 KFO96920.1 - 4.6 6.3 36.8 7.6 5.5 11.0 2.3 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region DUF4326 PF14216.6 KFO96920.1 - 5.2 7.9 11.4 1.1e+02 3.6 8.1 3.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4326) Pkinase PF00069.25 KFO96921.1 - 6.6e-38 130.6 0.0 4.7e-37 127.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO96921.1 - 4.3e-29 101.6 0.0 4.5e-26 91.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFO96921.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like ASXH PF13919.6 KFO96921.1 - 0.15 12.1 0.1 0.27 11.3 0.1 1.3 1 0 0 1 1 1 0 Asx homology domain TMEM237 PF15383.6 KFO96922.1 - 6e-100 333.5 0.3 8.5e-100 333.0 0.3 1.2 1 0 0 1 1 1 1 Transmembrane protein 237 Pap_E4 PF02711.14 KFO96922.1 - 7.4 7.6 9.1 5.3 8.1 1.3 2.4 2 0 0 2 2 2 0 E4 protein RCC1 PF00415.18 KFO96923.1 - 2.1e-39 133.9 17.5 3.3e-11 43.6 0.2 7.7 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat MORN PF02493.20 KFO96923.1 - 2.2e-26 90.2 31.6 2.6e-05 23.8 2.7 9.7 9 1 0 9 9 9 7 MORN repeat RCC1_2 PF13540.6 KFO96923.1 - 1.3e-25 88.6 29.1 1.6e-07 31.0 1.8 7.5 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat VPS9 PF02204.18 KFO96923.1 - 2e-24 85.8 0.1 2.6e-23 82.2 0.2 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain RhoGEF PF00621.20 KFO96923.1 - 3.2e-06 27.5 0.7 6.8e-06 26.4 0.7 1.6 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 KFO96923.1 - 0.0083 16.6 0.0 0.021 15.3 0.0 1.7 1 0 0 1 1 1 1 PH domain Vmethyltransf_C PF08456.10 KFO96923.1 - 0.15 11.6 0.0 0.34 10.4 0.0 1.6 1 0 0 1 1 1 0 Viral methyltransferase C-terminal SERTA PF06031.13 KFO96924.1 - 3.3e-17 61.9 0.8 5.4e-17 61.2 0.8 1.4 1 0 0 1 1 1 1 SERTA motif Clathrin_bdg PF15045.6 KFO96925.1 - 2.2e-20 72.5 0.0 1e-19 70.3 0.0 2.3 1 0 0 1 1 1 1 Clathrin-binding box of Aftiphilin, vesicle trafficking HrpB2 PF09487.10 KFO96925.1 - 0.17 12.3 0.7 6.3 7.3 0.0 2.5 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) Gal-bind_lectin PF00337.22 KFO96926.1 - 1.1e-32 112.4 0.0 1.2e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin DUF2189 PF09955.9 KFO96927.1 - 0.096 12.9 3.2 0.13 12.6 3.2 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2189) Pellino PF04710.14 KFO96928.1 - 6e-220 730.1 0.1 6.7e-220 729.9 0.1 1.0 1 0 0 1 1 1 1 Pellino Prok-RING_4 PF14447.6 KFO96928.1 - 0.013 15.3 7.6 1.4 8.9 3.7 3.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFO96928.1 - 0.055 13.3 10.1 1.3 8.9 0.7 3.6 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFO96928.1 - 0.36 10.8 0.1 0.36 10.8 0.1 3.6 2 1 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 KFO96928.1 - 0.47 10.8 10.8 0.58 10.5 0.2 3.2 3 0 0 3 3 3 0 Ring finger domain Vps54 PF07928.12 KFO96929.1 - 9.7e-50 168.5 0.9 4.8e-49 166.2 0.9 2.3 1 0 0 1 1 1 1 Vps54-like protein Vps54_N PF10475.9 KFO96929.1 - 8.7e-08 31.8 7.4 8.7e-08 31.8 7.4 2.7 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex CCDC24 PF15669.5 KFO96929.1 - 0.046 13.6 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family COG2 PF06148.11 KFO96929.1 - 0.14 12.2 4.4 11 6.1 0.0 3.4 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ASL_C PF08328.11 KFO96929.1 - 0.15 12.1 1.5 0.68 10.0 0.3 2.6 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminal UDPGP PF01704.18 KFO96930.1 - 4.9e-199 661.2 0.2 5.8e-199 660.9 0.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.6 KFO96930.1 - 0.055 12.3 0.2 5 5.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4301) Ldh_1_C PF02866.18 KFO96932.1 - 2.4e-44 151.2 0.1 4.9e-44 150.2 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KFO96932.1 - 1.4e-39 135.4 0.1 2.7e-39 134.5 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_3_C PF01915.22 KFO96932.1 - 0.012 15.5 0.4 0.033 14.1 0.0 1.8 1 1 1 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain DUF4809 PF16067.5 KFO96932.1 - 0.081 13.1 0.1 0.31 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4809) DUF840 PF05801.11 KFO96932.1 - 0.12 12.4 0.4 5.4 7.1 0.1 2.3 2 0 0 2 2 2 0 Lagovirus protein of unknown function (DUF840) Frtz PF11768.8 KFO96933.1 - 5.4e-253 840.3 0.2 6.2e-253 840.1 0.2 1.0 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz ANAPC4_WD40 PF12894.7 KFO96933.1 - 0.11 12.9 0.0 3.1 8.1 0.0 2.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Homeodomain PF00046.29 KFO96935.1 - 3e-23 81.4 1.4 3.4e-23 81.3 1.4 1.0 1 0 0 1 1 1 1 Homeodomain SatD PF16264.5 KFO96935.1 - 0.0053 16.4 0.1 0.0057 16.3 0.1 1.0 1 0 0 1 1 1 1 SatD family (SatD) Homeobox_KN PF05920.11 KFO96935.1 - 0.048 13.6 0.5 0.21 11.5 0.1 1.9 1 1 1 2 2 2 0 Homeobox KN domain Transmemb_17 PF09799.9 KFO96936.1 - 5.5e-29 100.9 13.8 7.4e-29 100.5 13.8 1.2 1 0 0 1 1 1 1 Predicted membrane protein DUF3043 PF11241.8 KFO96936.1 - 0.86 9.6 7.9 0.79 9.7 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3043) EGF_CA PF07645.15 KFO96937.1 - 2.7e-08 33.9 7.0 2.7e-08 33.9 7.0 2.1 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF_3 PF12947.7 KFO96937.1 - 0.00039 20.5 3.9 0.00076 19.6 3.9 1.4 1 0 0 1 1 1 1 EGF domain Plasmod_Pvs28 PF06247.11 KFO96937.1 - 0.0023 18.2 3.8 0.0042 17.4 3.8 1.5 1 0 0 1 1 1 1 Pvs28 EGF domain EGF_MSP1_1 PF12946.7 KFO96937.1 - 0.011 15.8 3.0 0.011 15.8 3.0 1.7 2 0 0 2 2 2 0 MSP1 EGF domain 1 hEGF PF12661.7 KFO96937.1 - 0.027 15.1 2.9 0.027 15.1 2.9 1.9 2 0 0 2 2 2 0 Human growth factor-like EGF EGF PF00008.27 KFO96937.1 - 0.13 12.6 6.1 0.12 12.7 4.0 2.0 2 0 0 2 2 2 0 EGF-like domain TMEM100 PF16311.5 KFO96937.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 100 Galactosyl_T PF01762.21 KFO96938.1 - 5.8e-42 143.7 0.0 9.6e-42 143.0 0.0 1.4 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 KFO96938.1 - 0.0028 17.1 0.0 0.0046 16.4 0.0 1.2 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.12 KFO96938.1 - 0.0061 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 COMMD1_N PF17221.3 KFO96939.1 - 1e-43 147.8 0.1 1.9e-43 147.0 0.0 1.5 2 0 0 2 2 2 1 COMMD1 N-terminal domain COMM_domain PF07258.14 KFO96939.1 - 2.7e-17 62.6 1.6 1.5e-16 60.2 1.2 2.1 2 1 0 2 2 2 1 COMM domain Herpes_BLRF2 PF05812.12 KFO96939.1 - 0.086 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein CDP-OH_P_transf PF01066.21 KFO96940.1 - 2e-12 47.7 0.3 2e-12 47.7 0.3 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase MCM PF00493.23 KFO96941.1 - 3.3e-83 278.2 0.0 4.7e-83 277.7 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 KFO96941.1 - 2.1e-27 95.3 0.5 4e-27 94.5 0.5 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 KFO96941.1 - 2.3e-24 85.6 1.3 4.5e-24 84.7 1.3 1.5 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 KFO96941.1 - 3.2e-08 33.2 0.0 5.9e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFO96941.1 - 1.4e-07 31.6 0.0 3.5e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFO96941.1 - 0.00018 21.4 0.0 0.00047 20.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFO96941.1 - 0.0038 17.6 0.6 0.051 13.9 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 KFO96941.1 - 0.008 16.6 0.0 0.023 15.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KFO96941.1 - 0.027 14.4 0.1 1.4 8.8 0.1 2.6 2 0 0 2 2 2 0 NTPase FtsK_SpoIIIE PF01580.18 KFO96941.1 - 0.033 13.5 0.0 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.6 KFO96941.1 - 0.071 13.4 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFO96941.1 - 0.092 12.2 0.0 0.32 10.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region Gcd10p PF04189.13 KFO96942.1 - 6.9e-66 222.4 3.3 6.9e-66 222.4 3.3 1.9 1 1 1 2 2 2 1 Gcd10p family CDC45 PF02724.14 KFO96942.1 - 9 4.4 13.8 0.3 9.4 5.5 1.9 2 0 0 2 2 2 0 CDC45-like protein Granin PF01271.17 KFO96943.1 - 3.2e-23 82.5 118.9 6.9e-23 81.4 118.9 1.5 1 1 0 1 1 1 1 Granin (chromogranin or secretogranin) UPF0020 PF01170.18 KFO96944.1 - 2.6e-28 99.1 0.0 2.8e-27 95.7 0.0 2.5 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 KFO96944.1 - 4.8e-13 49.6 0.0 1e-12 48.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFO96944.1 - 7.8e-13 48.5 0.0 1.3e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFO96944.1 - 1.6e-11 44.7 0.0 6.3e-11 42.8 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain THUMP PF02926.17 KFO96944.1 - 3.7e-08 33.6 0.0 7.8e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 THUMP domain Ubie_methyltran PF01209.18 KFO96944.1 - 2.8e-07 30.1 0.0 4.4e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KFO96944.1 - 3.1e-07 30.1 0.0 5.1e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain N6_Mtase PF02384.16 KFO96944.1 - 0.0092 15.3 0.0 0.024 13.9 0.0 1.6 1 1 0 1 1 1 1 N-6 DNA Methylase CMAS PF02353.20 KFO96944.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase AviRa PF11599.8 KFO96944.1 - 0.031 13.8 0.0 0.16 11.4 0.0 1.9 1 1 1 2 2 2 0 RRNA methyltransferase AviRa Methyltransf_12 PF08242.12 KFO96944.1 - 0.033 14.9 0.0 0.084 13.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 KFO96944.1 - 0.077 12.4 0.0 0.65 9.4 0.0 2.2 1 1 0 1 1 1 0 Putative methyltransferase AAA_lid_5 PF17865.1 KFO96944.1 - 0.081 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Midasin AAA lid domain MARVEL PF01284.23 KFO96945.1 - 8.8e-12 45.3 14.8 1.4e-11 44.6 14.8 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF2070 PF09843.9 KFO96945.1 - 0.27 9.5 8.7 0.32 9.3 8.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ribosomal_S5_C PF03719.15 KFO96946.1 - 1.5e-23 82.0 0.2 2.6e-23 81.3 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KFO96946.1 - 2e-16 59.7 2.3 2e-16 59.7 2.3 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Yae1_N PF09811.9 KFO96947.1 - 7.7e-18 63.9 63.5 1.8e+04 -28.3 63.5 6.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Calx-beta PF03160.14 KFO96948.1 - 3.7e-62 206.7 6.0 1.8e-35 121.1 0.8 2.6 2 0 0 2 2 2 2 Calx-beta domain Na_Ca_ex PF01699.24 KFO96948.1 - 7.1e-60 201.3 31.5 1e-33 116.4 11.4 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Na_Ca_ex_C PF16494.5 KFO96948.1 - 3.2e-51 173.1 5.8 5.1e-51 172.4 5.8 1.3 1 0 0 1 1 1 1 C-terminal extension of sodium/calcium exchanger domain DnaG_DnaB_bind PF08278.11 KFO96948.1 - 0.078 13.6 2.0 0.15 12.6 2.0 1.4 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding DUF2922 PF11148.8 KFO96950.1 - 0.046 13.5 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) Elf4 PF07011.11 KFO96950.1 - 0.069 13.1 5.1 4.1 7.4 0.1 2.6 2 0 0 2 2 2 0 Early Flowering 4 domain CarD_CdnL_TRCF PF02559.16 KFO96950.1 - 0.085 13.6 1.7 0.21 12.3 1.7 1.9 1 1 0 1 1 1 0 CarD-like/TRCF domain MAD PF05557.13 KFO96950.1 - 0.092 11.1 29.1 0.12 10.8 29.1 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Ldh_1_N PF00056.23 KFO96950.1 - 0.12 12.4 0.2 0.23 11.6 0.2 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain BSD PF03909.17 KFO96950.1 - 2 8.5 5.9 5 7.2 0.1 3.2 4 0 0 4 4 4 0 BSD domain DUF4407 PF14362.6 KFO96950.1 - 4 6.7 22.0 5 6.4 22.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1241 PF06840.11 KFO96950.1 - 4 7.1 14.5 1.4 8.6 1.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1241) Asp-B-Hydro_N PF05279.11 KFO96950.1 - 9.1 6.3 15.1 12 5.9 15.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DEAD PF00270.29 KFO96951.1 - 1.2e-42 145.7 0.2 1.8e-42 145.1 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFO96951.1 - 2.6e-32 111.4 0.0 1.5e-31 109.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFO96951.1 - 0.00013 22.1 0.0 0.00027 21.0 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KFO96951.1 - 0.0002 21.7 0.0 0.0022 18.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFO96951.1 - 0.00021 21.0 0.0 0.00033 20.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain UTP25 PF06862.12 KFO96951.1 - 0.0064 15.3 0.0 1.1 7.9 0.0 2.1 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 KFO96951.1 - 0.048 13.9 0.0 0.3 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.14 KFO96951.1 - 0.11 12.4 0.2 0.42 10.6 0.1 2.2 1 1 1 2 2 2 0 Flavivirus DEAD domain ERCC3_RAD25_C PF16203.5 KFO96951.1 - 0.11 11.6 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Fanconi_A PF03511.14 KFO96951.1 - 0.19 11.7 0.3 1.5 8.8 0.0 2.3 3 0 0 3 3 3 0 Fanconi anaemia group A protein GBP PF02263.19 KFO96952.1 - 1.4e-102 342.4 0.1 1.8e-102 342.0 0.1 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 KFO96952.1 - 1.9e-06 27.5 0.1 3.8e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain Tiam_CC_Ex PF18385.1 KFO96952.1 - 0.0057 17.0 0.0 0.021 15.2 0.0 1.9 1 0 0 1 1 1 1 T-lymphoma invasion and metastasis CC-Ex domain DUF2939 PF11159.8 KFO96952.1 - 0.15 12.5 0.0 12 6.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) RRM_5 PF13893.6 KFO96953.1 - 1.4e-58 195.9 3.5 4e-55 184.7 0.1 3.2 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KFO96953.1 - 8.6e-18 63.9 1.3 4.9e-07 29.5 0.1 4.4 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KFO96953.1 - 6.6e-10 39.1 0.1 2.8e-09 37.0 0.0 2.1 3 0 0 3 3 3 1 RRM-like domain RRM_occluded PF16842.5 KFO96953.1 - 0.00011 22.0 0.0 0.69 9.8 0.0 2.6 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_3 PF08777.11 KFO96953.1 - 0.0016 18.4 0.0 0.0058 16.6 0.0 1.9 2 0 0 2 2 2 1 RNA binding motif Limkain-b1 PF11608.8 KFO96953.1 - 0.0056 16.7 0.1 1.2 9.2 0.0 3.1 3 0 0 3 3 3 1 Limkain b1 DUF4523 PF15023.6 KFO96953.1 - 0.11 12.3 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) RL PF17797.1 KFO96953.1 - 0.13 12.2 0.1 28 4.7 0.0 3.2 3 0 0 3 3 3 0 RL domain Aldose_epim PF01263.20 KFO96955.1 - 3.8e-99 331.8 0.0 4.3e-99 331.6 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase RRM_1 PF00076.22 KFO96956.1 - 8.3e-17 60.8 0.0 1.2e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFO96956.1 - 0.00058 19.5 0.0 0.0009 18.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KFO96956.1 - 0.0006 19.8 7.7 0.0012 18.8 7.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KFO96956.1 - 0.00083 19.3 2.2 0.0019 18.1 2.2 1.7 1 0 0 1 1 1 1 Zinc knuckle Gemin6 PF06372.12 KFO96957.1 - 4.7e-65 218.2 0.7 5.2e-65 218.0 0.7 1.0 1 0 0 1 1 1 1 Gemin6 protein RRM_1 PF00076.22 KFO96958.1 - 5e-16 58.3 0.0 7e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KFO96958.1 - 0.00057 19.8 7.7 0.0011 18.9 7.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KFO96958.1 - 0.0008 19.3 2.4 0.0019 18.1 2.4 1.7 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.6 KFO96958.1 - 0.0021 17.6 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFO96958.1 - 0.058 13.3 0.0 0.078 12.8 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif OB_NTP_bind PF07717.16 KFO96959.1 - 7.1e-17 61.5 0.0 1.1e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RhoGEF PF00621.20 KFO96960.1 - 3.5e-16 60.0 5.7 4.3e-16 59.7 5.7 1.1 1 0 0 1 1 1 1 RhoGEF domain RasGEF PF00617.19 KFO96962.1 - 2.5e-49 167.9 0.4 5.3e-49 166.8 0.4 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KFO96962.1 - 9.8e-32 109.3 0.0 3.4e-31 107.6 0.0 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif RhoGEF PF00621.20 KFO96962.1 - 2.2e-16 60.7 1.5 5.6e-16 59.3 0.1 2.4 2 0 0 2 2 2 1 RhoGEF domain Histone PF00125.24 KFO96962.1 - 1.6e-12 48.0 0.0 4.4e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PH PF00169.29 KFO96962.1 - 5.1e-11 43.0 2.4 5.6e-11 42.9 0.0 2.4 3 0 0 3 3 3 1 PH domain PH_10 PF15411.6 KFO96962.1 - 0.0013 19.0 0.1 0.0048 17.2 0.1 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 KFO96962.1 - 0.0017 18.3 0.0 0.0069 16.4 0.0 2.0 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 KFO96962.1 - 0.0037 17.1 0.8 0.0088 15.9 0.1 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain DUF445 PF04286.12 KFO96962.1 - 0.13 12.0 3.9 7.9 6.2 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF445) Pkinase PF00069.25 KFO96963.1 - 3.8e-63 213.3 0.0 5.3e-63 212.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CNH PF00780.22 KFO96963.1 - 3.4e-56 190.9 0.3 5.4e-56 190.2 0.3 1.3 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.17 KFO96963.1 - 8.4e-40 136.7 0.0 1.3e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFO96963.1 - 0.0012 17.8 0.0 0.0024 16.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KFO96963.1 - 0.024 14.0 0.1 0.13 11.5 0.0 2.0 2 0 0 2 2 2 0 Kinase-like IBR PF01485.21 KFO96964.1 - 2.9e-11 43.4 34.9 2.6e-08 34.0 8.6 3.3 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain Cullin_Nedd8 PF10557.9 KFO96965.1 - 4.3e-10 39.5 0.0 5.4e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Cullin protein neddylation domain Cul7 PF11515.8 KFO96966.1 - 5.1e-27 94.0 0.3 9.4e-27 93.1 0.3 1.5 1 0 0 1 1 1 1 Mouse development and cellular proliferation protein Cullin-7 SRF-TF PF00319.18 KFO96967.1 - 8.9e-07 28.3 0.0 1.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) I-set PF07679.16 KFO96968.1 - 1.2e-85 281.7 0.0 9.8e-15 54.4 0.0 7.4 7 0 0 7 7 7 7 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO96968.1 - 1.2e-85 282.1 8.6 1.9e-13 50.8 0.2 7.4 7 0 0 7 7 7 7 Immunoglobulin domain Pkinase_Tyr PF07714.17 KFO96968.1 - 1.5e-82 276.8 0.0 2.1e-82 276.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ig_2 PF13895.6 KFO96968.1 - 3e-65 216.5 7.4 2.9e-11 43.5 0.1 7.7 7 1 0 7 7 7 6 Immunoglobulin domain ig PF00047.25 KFO96968.1 - 8.8e-48 160.4 3.4 1.4e-07 31.6 0.0 7.5 7 0 0 7 7 7 7 Immunoglobulin domain Pkinase PF00069.25 KFO96968.1 - 9.2e-40 136.7 0.0 1.4e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain V-set PF07686.17 KFO96968.1 - 1.8e-25 89.2 10.9 0.021 15.0 0.6 10.0 7 3 2 9 9 9 6 Immunoglobulin V-set domain Ig_6 PF18452.1 KFO96968.1 - 6.5e-20 70.4 0.6 0.011 15.2 0.0 7.1 7 0 0 7 7 7 5 Immunoglobulin domain Ig_5 PF16681.5 KFO96968.1 - 3.6e-17 62.5 0.1 0.021 15.2 0.0 7.0 7 1 0 7 7 6 4 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KFO96968.1 - 1.2e-15 57.3 8.7 0.0049 16.9 0.1 6.7 6 0 0 6 6 6 5 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFO96968.1 - 9.3e-11 41.8 1.1 0.5 10.7 0.0 6.8 7 1 0 7 7 7 3 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 KFO96968.1 - 1.2e-08 35.2 1.0 0.22 11.9 0.0 5.7 5 0 0 5 5 5 2 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 KFO96968.1 - 1.2e-07 31.7 0.2 2.9 8.0 0.0 6.4 6 0 0 6 6 6 2 Izumo-like Immunoglobulin domain V-set_CD47 PF08204.11 KFO96968.1 - 2.3e-05 24.4 0.4 0.54 10.3 0.0 4.0 4 0 0 4 4 4 2 CD47 immunoglobulin-like domain C2-set PF05790.15 KFO96968.1 - 3.8e-05 23.8 1.4 10 6.4 0.0 6.1 7 0 0 7 7 6 0 Immunoglobulin C2-set domain UL141 PF16758.5 KFO96968.1 - 0.0092 15.7 0.2 27 4.4 0.0 4.1 3 1 1 4 4 4 0 Herpes-like virus membrane glycoprotein UL141 Adeno_E3_CR1 PF02440.15 KFO96968.1 - 0.024 14.4 2.5 5.6 6.8 0.0 4.8 5 1 1 6 6 6 0 Adenovirus E3 region protein CR1 CD34_antigen PF06365.12 KFO96968.1 - 0.052 13.1 0.1 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 CD34/Podocalyxin family Ig_C17orf99 PF17736.1 KFO96968.1 - 0.066 13.3 6.0 27 4.9 0.0 5.4 5 2 0 5 5 5 0 C17orf99 Ig domain LVIVD PF08309.11 KFO96968.1 - 0.098 12.0 0.1 14 5.1 0.0 3.1 2 1 1 3 3 3 0 LVIVD repeat TPR_12 PF13424.6 KFO96969.1 - 3.3e-71 235.6 23.5 1.5e-20 73.3 1.2 5.5 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 KFO96969.1 - 1.6e-57 189.9 15.4 1.2e-15 56.8 0.0 7.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 KFO96969.1 - 9.3e-27 91.7 29.2 1.3e-07 31.1 0.5 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 KFO96969.1 - 1.7e-26 90.3 14.2 4e-06 26.5 0.0 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 KFO96969.1 - 1e-18 65.9 25.6 0.00065 19.6 0.4 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KFO96969.1 - 6e-15 54.1 22.5 0.0014 18.7 0.1 6.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KFO96969.1 - 2.4e-14 53.5 6.1 6.8e-13 48.7 0.4 3.0 3 0 0 3 3 3 1 MalT-like TPR region TPR_16 PF13432.6 KFO96969.1 - 1.1e-13 51.6 3.2 0.0015 19.1 1.2 5.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFO96969.1 - 7.2e-13 48.8 5.9 0.00017 22.1 0.0 4.8 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFO96969.1 - 1.5e-09 37.6 11.5 0.068 13.6 0.1 6.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFO96969.1 - 3.3e-09 36.8 5.4 5.3 8.1 0.2 6.7 3 1 3 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO96969.1 - 2.9e-07 30.6 11.0 0.0038 17.4 0.1 4.0 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 KFO96969.1 - 5.7e-07 29.5 1.7 1.8 9.4 0.2 6.7 8 0 0 8 8 6 1 Tetratricopeptide repeat PPR PF01535.20 KFO96969.1 - 0.00024 21.2 3.4 0.088 13.1 0.0 4.6 6 0 0 6 6 3 1 PPR repeat JIP_LZII PF16471.5 KFO96969.1 - 0.0027 17.8 5.3 0.0027 17.8 5.3 2.6 2 1 0 2 2 2 1 JNK-interacting protein leucine zipper II Uso1_p115_C PF04871.13 KFO96969.1 - 0.0027 18.1 10.8 0.0027 18.1 10.8 2.4 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region DUF627 PF04781.12 KFO96969.1 - 0.0075 16.3 3.9 0.33 11.0 0.1 3.7 2 2 1 3 3 3 1 Protein of unknown function (DUF627) PPR_2 PF13041.6 KFO96969.1 - 0.02 15.1 0.8 3.3 8.0 0.0 3.4 3 0 0 3 3 3 0 PPR repeat family TMF_TATA_bd PF12325.8 KFO96969.1 - 0.02 15.1 10.4 0.02 15.1 10.4 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding SHNi-TPR PF10516.9 KFO96969.1 - 0.029 13.8 2.4 5.2 6.6 0.1 4.1 4 0 0 4 4 4 0 SHNi-TPR GHL5 PF14872.6 KFO96969.1 - 0.055 11.5 2.1 0.081 11.0 2.1 1.2 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 Csm1_N PF18504.1 KFO96969.1 - 0.12 12.7 8.8 0.62 10.4 8.2 2.7 1 1 0 1 1 1 0 Csm1 N-terminal domain WbqC PF08889.11 KFO96969.1 - 0.27 11.1 2.6 10 5.9 0.0 3.4 3 1 1 4 4 3 0 WbqC-like protein family COG2 PF06148.11 KFO96969.1 - 0.38 10.8 8.5 0.22 11.6 5.8 1.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Macoilin PF09726.9 KFO96969.1 - 0.49 8.9 9.5 0.75 8.3 9.5 1.3 1 0 0 1 1 1 0 Macoilin family DUF3450 PF11932.8 KFO96969.1 - 0.54 9.5 9.8 1.2 8.4 9.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) RasGAP_C PF03836.15 KFO96969.1 - 0.76 9.9 10.7 1.2 9.3 9.3 2.1 1 1 0 1 1 1 0 RasGAP C-terminus Spc7 PF08317.11 KFO96969.1 - 0.8 8.5 18.4 1.5 7.6 18.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein SOGA PF11365.8 KFO96969.1 - 2.4 9.4 16.7 3.7 8.7 5.6 3.8 1 1 1 3 3 3 0 Protein SOGA DUF3972 PF13118.6 KFO96969.1 - 2.4 8.6 11.5 1.4e+02 2.9 11.4 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3972) FapA PF03961.13 KFO96969.1 - 2.7 6.5 8.1 4.3 5.8 8.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A YabA PF06156.13 KFO96969.1 - 2.8 8.6 16.4 0.088 13.5 4.7 3.5 3 0 0 3 3 3 0 Initiation control protein YabA TPR_11 PF13414.6 KFO96969.1 - 3.9 7.3 17.8 0.87 9.3 0.2 5.8 6 0 0 6 6 6 0 TPR repeat MIT PF04212.18 KFO96969.1 - 7.3 6.7 19.6 9.2 6.4 0.8 6.2 5 1 2 7 7 6 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 KFO96969.1 - 8.6 7.2 16.2 4.2 8.2 0.1 6.0 7 0 0 7 7 5 0 Tetratricopeptide repeat Ribosomal_L2_C PF03947.18 KFO96970.1 - 8.2e-31 106.8 0.2 1.5e-30 106.0 0.2 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KFO96970.1 - 1.5e-14 53.7 0.8 2.5e-14 53.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Cul7 PF11515.8 KFO96971.1 - 1.3e-34 118.3 0.1 2.1e-34 117.6 0.1 1.3 1 0 0 1 1 1 1 Mouse development and cellular proliferation protein Cullin-7 Cullin PF00888.22 KFO96972.1 - 5.9e-07 28.5 0.0 8.2e-07 28.0 0.0 1.4 1 1 0 1 1 1 1 Cullin family ANAPC10 PF03256.16 KFO96972.1 - 0.0054 16.4 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Cullin_Nedd8 PF10557.9 KFO96973.1 - 7.3e-11 41.9 0.1 9.5e-11 41.6 0.1 1.1 1 0 0 1 1 1 1 Cullin protein neddylation domain Pacs-1 PF10254.9 KFO96974.1 - 1.1e-194 647.2 0.0 2.1e-194 646.2 0.0 1.5 1 0 0 1 1 1 1 PACS-1 cytosolic sorting protein hNIFK_binding PF12196.8 KFO96974.1 - 0.19 11.3 1.2 0.59 9.7 1.2 1.9 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK CECR6_TMEM121 PF14997.6 KFO96975.1 - 4.7e-61 206.0 13.8 4.7e-61 206.0 13.8 1.4 2 0 0 2 2 2 1 CECR6/TMEM121 family DUF5083 PF16890.5 KFO96975.1 - 0.0035 17.1 1.6 0.0035 17.1 1.6 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5083) DUF565 PF04483.12 KFO96975.1 - 3.6 8.2 7.6 19 5.9 0.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF565) RRP36 PF06102.12 KFO96976.1 - 6.4e-46 156.4 32.1 7.5e-46 156.1 32.1 1.0 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 SprA-related PF12118.8 KFO96976.1 - 5.1 6.1 9.9 6.1 5.9 9.9 1.1 1 0 0 1 1 1 0 SprA-related family Ureide_permease PF07168.11 KFO96976.1 - 7.2 5.3 6.5 9.2 4.9 6.5 1.1 1 0 0 1 1 1 0 Ureide permease B56 PF01603.20 KFO96977.1 - 3.3e-200 665.4 5.9 4.2e-200 665.0 5.9 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Stm1_N PF09598.10 KFO96977.1 - 0.33 11.8 6.2 0.91 10.4 6.2 1.8 1 0 0 1 1 1 0 Stm1 Hydrolase_4 PF12146.8 KFO96978.1 - 2e-17 63.3 0.0 7.6e-14 51.6 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFO96978.1 - 1.5e-15 57.6 0.4 1.9e-13 50.7 0.3 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFO96978.1 - 2e-09 38.4 0.8 6.3e-09 36.7 0.8 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KFO96978.1 - 0.00052 19.9 0.0 0.001 18.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KFO96978.1 - 0.0069 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.21 KFO96978.1 - 0.0094 15.4 0.0 0.046 13.2 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KFO96978.1 - 0.034 13.7 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 KFO96978.1 - 0.04 13.7 0.0 0.22 11.3 0.0 2.1 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Say1_Mug180 PF10340.9 KFO96978.1 - 0.1 11.4 0.0 0.22 10.3 0.0 1.6 1 1 0 1 1 1 0 Steryl acetyl hydrolase Chlorophyllase2 PF12740.7 KFO96978.1 - 0.15 11.0 0.0 0.87 8.4 0.0 1.9 1 1 0 1 1 1 0 Chlorophyllase enzyme LIP PF03583.14 KFO96978.1 - 0.22 10.8 0.0 0.48 9.7 0.0 1.5 2 0 0 2 2 2 0 Secretory lipase Phosphorylase PF00343.20 KFO96979.1 - 0 1152.3 0.0 0 1152.1 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase TPR_22 PF18833.1 KFO96979.1 - 0.0003 20.9 0.1 0.00073 19.6 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat GDA1_CD39 PF01150.17 KFO96980.1 - 9e-75 251.9 0.0 4.6e-74 249.6 0.0 2.0 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF1507 PF07408.11 KFO96980.1 - 0.063 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1507) Ppx-GppA PF02541.16 KFO96980.1 - 0.092 12.2 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Homeodomain PF00046.29 KFO96981.1 - 9.1e-24 83.1 2.6 1.8e-23 82.1 2.6 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO96981.1 - 0.0049 16.8 0.1 0.012 15.5 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Methyltransf_31 PF13847.6 KFO96982.1 - 4.3e-08 33.1 0.0 1e-07 31.9 0.0 1.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFO96982.1 - 2.5e-06 28.1 0.0 4.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFO96982.1 - 3.8e-06 27.6 0.0 6.3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFO96982.1 - 2.1e-05 25.1 0.0 3.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFO96982.1 - 0.0094 15.8 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF3456 PF11938.8 KFO96983.1 - 7.7e-29 101.2 0.2 8.5e-29 101.1 0.2 1.0 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP RNA_pol_Rpb2_6 PF00562.28 KFO96984.1 - 1.3e-115 386.6 0.0 3.7e-115 385.1 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 KFO96984.1 - 6.7e-27 93.5 0.0 1.3e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_1 PF04563.15 KFO96984.1 - 5e-25 88.2 0.1 1e-24 87.2 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KFO96984.1 - 5.6e-21 74.7 0.0 1.5e-20 73.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.12 KFO96984.1 - 6.3e-19 67.7 0.0 1.2e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 KFO96984.1 - 1.9e-13 50.5 0.0 3.3e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 TTL PF03133.15 KFO96985.1 - 3e-68 230.1 0.1 8e-68 228.7 0.1 1.6 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KFO96985.1 - 3.8e-07 29.6 0.2 6.9e-06 25.5 0.0 2.4 2 1 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KFO96985.1 - 0.016 14.5 0.0 0.48 9.6 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 KFO96985.1 - 0.16 12.0 0.0 1.8 8.6 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain Sugar_tr PF00083.24 KFO96986.1 - 5.5e-33 114.5 20.5 7.1e-33 114.1 20.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFO96986.1 - 6.8e-31 107.5 26.1 9.2e-31 107.0 26.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KFO96986.1 - 0.086 11.2 11.0 0.0083 14.6 6.0 1.6 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KFO96986.1 - 5.9 5.3 28.6 0.012 14.2 9.6 3.0 2 1 1 3 3 3 0 MFS/sugar transport protein UPF0182 PF03699.13 KFO96986.1 - 6.5 4.7 8.5 0.17 10.0 2.1 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0182) Pkinase PF00069.25 KFO96987.1 - 4.2e-32 111.5 0.0 6.6e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO96987.1 - 1e-19 70.8 0.0 1.6e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFO96987.1 - 0.038 12.8 0.0 0.11 11.2 0.0 1.8 1 0 0 1 1 1 0 Fungal protein kinase Sigma70_ner PF04546.13 KFO96987.1 - 0.2 11.5 7.6 0.49 10.3 7.6 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.12 KFO96987.1 - 8.7 5.6 11.1 18 4.5 11.1 1.4 1 0 0 1 1 1 0 NOA36 protein AMP-binding PF00501.28 KFO96988.1 - 2.7e-91 306.3 0.1 3.2e-91 306.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFO96988.1 - 2.7e-23 82.7 2.1 9.4e-23 81.0 0.8 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF1967 PF09269.11 KFO96988.1 - 0.17 11.9 0.0 0.86 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) Str_synth PF03088.16 KFO96989.1 - 1.7e-29 101.8 0.1 5.3e-29 100.2 0.0 2.0 2 0 0 2 2 2 1 Strictosidine synthase SGL PF08450.12 KFO96989.1 - 3.6e-15 56.2 0.0 5e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KFO96989.1 - 0.00048 20.3 0.0 0.061 13.5 0.0 2.8 2 1 0 2 2 2 1 Arylesterase NHL PF01436.21 KFO96989.1 - 0.00078 19.4 0.0 0.18 11.9 0.0 3.9 4 0 0 4 4 4 1 NHL repeat PQQ_3 PF13570.6 KFO96989.1 - 0.048 14.2 0.0 3.5 8.2 0.0 3.3 3 1 0 3 3 3 0 PQQ-like domain PQQ_2 PF13360.6 KFO96989.1 - 0.14 11.7 0.0 1.7 8.2 0.0 2.3 1 1 0 1 1 1 0 PQQ-like domain Cystatin PF00031.21 KFO96990.1 - 1.3e-15 57.4 0.0 1.5e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 KFO96990.1 - 0.00038 20.8 0.0 0.00053 20.3 0.0 1.2 1 0 0 1 1 1 1 Aspartic acid proteinase inhibitor N-glycanase_N PF09112.10 KFO96990.1 - 0.085 12.6 0.3 0.28 11.0 0.3 1.8 1 1 0 1 1 1 0 Peptide-N-glycosidase F, N terminal CD225 PF04505.12 KFO96991.1 - 1.4e-18 66.8 0.1 2.2e-18 66.1 0.1 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein T-box PF00907.22 KFO96992.1 - 2e-40 139.0 0.0 3e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 T-box PDEase_I PF00233.19 KFO96993.1 - 5.4e-72 242.4 0.3 1.4e-70 237.7 0.1 2.2 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 KFO96993.1 - 1.7e-28 99.9 0.0 1.6e-18 67.6 0.0 2.4 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 KFO96993.1 - 1.8e-18 67.2 0.0 8.2e-09 35.9 0.0 2.3 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 KFO96993.1 - 7.8e-09 36.0 0.0 1.2e-05 25.6 0.0 2.6 2 0 0 2 2 2 2 GAF domain SpoVT_C PF15714.5 KFO96993.1 - 1.2e-05 25.4 0.0 0.003 17.6 0.0 2.5 2 0 0 2 2 2 2 Stage V sporulation protein T C-terminal, transcription factor HD PF01966.22 KFO96993.1 - 0.051 13.8 0.2 0.12 12.6 0.2 1.6 1 0 0 1 1 1 0 HD domain H_kinase_N PF12282.8 KFO96993.1 - 0.068 13.1 0.0 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 Signal transduction histidine kinase DUF4748 PF15932.5 KFO96993.1 - 0.18 11.6 0.0 0.44 10.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Quaking_NLS PF16551.5 KFO96994.1 - 1.3e-16 60.0 5.7 2.2e-16 59.2 5.7 1.4 1 0 0 1 1 1 1 Putative nuclear localisation signal of quaking KH_1 PF00013.29 KFO96994.1 - 1.7e-06 27.7 0.0 4.3e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 KH domain STAR_dimer PF16544.5 KFO96994.1 - 0.00031 20.3 0.1 0.00059 19.3 0.1 1.5 1 0 0 1 1 1 1 Homodimerisation region of STAR domain protein RVT_1 PF00078.27 KFO96995.1 - 0.00017 21.2 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.11 KFO96995.1 - 0.22 11.2 0.6 0.38 10.5 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) zf-RING_12 PF17976.1 KFO96996.1 - 2.6e-39 133.3 5.8 6.6e-39 132.0 5.8 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_14 PF17978.1 KFO96996.1 - 9e-27 93.3 7.0 1.9e-26 92.3 7.0 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain CTNNB1_binding PF08347.11 KFO96997.1 - 3.7e-52 177.4 8.1 3.7e-52 177.4 8.1 2.1 2 0 0 2 2 2 1 N-terminal CTNNB1 binding HMG_box PF00505.19 KFO96997.1 - 5.3e-22 78.0 0.7 5.3e-22 78.0 0.7 2.5 3 1 1 4 4 4 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFO96997.1 - 5.7e-09 36.4 0.8 1.8e-08 34.9 0.8 1.8 1 0 0 1 1 1 1 HMG-box domain 3HCDH_N PF02737.18 KFO96998.1 - 2.6e-53 180.6 1.6 3.3e-53 180.2 1.6 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KFO96998.1 - 4.9e-35 120.0 0.0 1.1e-34 118.9 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain p450 PF00067.22 KFO96999.1 - 9e-106 354.4 0.4 1.1e-105 354.1 0.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cep3 PF16846.5 KFO96999.1 - 0.2 10.1 1.6 1.9 6.9 0.1 2.2 2 1 0 2 2 2 0 Centromere DNA-binding protein complex CBF3 subunit B PAP2_C PF14360.6 KFO97000.1 - 8.5e-28 96.7 14.3 8.5e-28 96.7 14.3 2.3 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 KFO97000.1 - 1.7e-05 24.6 11.9 1.7e-05 24.6 11.9 2.1 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KFO97000.1 - 0.15 11.8 16.3 0.1 12.3 11.8 2.2 2 1 0 2 2 2 0 PAP2 superfamily APS_kinase PF01583.20 KFO97001.1 - 1.1e-74 249.6 0.0 1.7e-74 249.0 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.17 KFO97001.1 - 5.8e-70 235.1 0.0 8.3e-70 234.6 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 KFO97001.1 - 5.2e-50 169.2 0.0 9.6e-50 168.4 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.6 KFO97001.1 - 1.4e-07 31.7 0.0 3.1e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFO97001.1 - 0.00042 20.9 0.0 0.0015 19.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 KFO97001.1 - 0.041 13.6 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase KTI12 PF08433.10 KFO97001.1 - 0.045 13.2 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PRK PF00485.18 KFO97001.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family 6PF2K PF01591.18 KFO97001.1 - 0.086 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase PEPCK_ATP PF01293.20 KFO97001.1 - 0.089 11.4 0.1 1.2 7.7 0.1 2.0 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase AAA_28 PF13521.6 KFO97001.1 - 0.099 12.9 0.1 0.73 10.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KFO97001.1 - 0.18 11.1 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 KFO97001.1 - 0.19 12.1 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Prokineticin PF06607.11 KFO97002.1 - 0.021 15.1 7.2 0.026 14.8 7.2 1.1 1 0 0 1 1 1 0 Prokineticin Toxin_21 PF08091.11 KFO97002.1 - 0.021 14.7 2.5 0.021 14.7 2.5 2.1 2 0 0 2 2 2 0 Spider insecticidal peptide Dickkopf_N PF04706.12 KFO97002.1 - 0.2 12.2 12.7 0.52 10.8 10.3 2.1 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Mucin-like PF16058.5 KFO97003.1 - 0.00067 19.7 43.9 0.0042 17.1 14.9 2.9 1 1 2 3 3 3 2 Mucin-like Ste5 PF11610.8 KFO97003.1 - 3.4 7.6 28.9 74 3.3 0.1 8.0 8 1 0 9 9 9 0 Scaffold protein Ste5, Fus3-binding region AIG1 PF04548.16 KFO97004.1 - 4.8e-26 91.4 0.0 6.1e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 KFO97004.1 - 8.2e-05 22.7 0.0 0.00015 21.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KFO97004.1 - 0.035 13.5 0.2 0.077 12.3 0.1 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Septin PF00735.18 KFO97004.1 - 0.058 12.7 0.0 0.085 12.1 0.0 1.3 1 0 0 1 1 1 0 Septin tRNA_bind PF01588.20 KFO97005.1 - 1.1e-30 105.6 0.5 4e-30 103.8 0.1 2.1 2 0 0 2 2 2 1 Putative tRNA binding domain Ribosomal_60s PF00428.19 KFO97005.1 - 0.053 14.1 6.7 0.13 12.9 6.7 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein SpoOE-like PF09388.10 KFO97005.1 - 0.13 12.2 3.2 0.28 11.1 2.0 2.0 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein NUDE_C PF04880.13 KFO97005.1 - 4 7.9 9.0 14 6.1 9.1 1.8 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region SlyX PF04102.12 KFO97005.1 - 4.1 8.1 7.7 1e+02 3.6 7.7 2.7 1 1 0 1 1 1 0 SlyX PRP1_N PF06424.12 KFO97005.1 - 4.5 7.7 10.8 3.2 8.1 4.1 2.3 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal RabGAP-TBC PF00566.18 KFO97006.1 - 4.4e-43 147.4 0.1 7e-43 146.8 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 KFO97006.1 - 1.1e-37 129.8 0.0 1.6e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO97006.1 - 4.7e-26 91.6 0.0 8.1e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Rhodanese PF00581.20 KFO97006.1 - 1.4e-13 51.3 0.0 2.8e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Kinase-like PF14531.6 KFO97006.1 - 5.5e-06 25.9 0.0 9.4e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like EGF_CA PF07645.15 KFO97007.1 - 1e-23 83.2 63.7 2e-10 40.7 3.7 5.7 4 2 1 5 5 5 3 Calcium-binding EGF domain MAM PF00629.23 KFO97007.1 - 3.1e-20 72.7 0.0 6.9e-20 71.6 0.0 1.6 1 1 0 1 1 1 1 MAM domain, meprin/A5/mu cEGF PF12662.7 KFO97007.1 - 2.6e-18 65.6 47.7 1.7e-07 31.0 0.9 5.9 6 0 0 6 6 6 5 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFO97007.1 - 2.4e-09 37.3 78.5 4.4e-05 23.7 9.3 5.6 5 0 0 5 5 5 4 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 KFO97007.1 - 1.9e-05 24.8 66.9 4.4e-05 23.6 13.2 6.0 4 1 1 5 5 5 3 EGF domain EGF PF00008.27 KFO97007.1 - 3.5e-05 24.0 75.9 0.1 13.0 9.1 6.4 5 1 1 6 6 6 4 EGF-like domain Plasmod_Pvs28 PF06247.11 KFO97007.1 - 0.00033 20.9 7.3 0.00033 20.9 7.3 4.6 4 1 0 4 4 4 3 Pvs28 EGF domain EGF_2 PF07974.13 KFO97007.1 - 0.011 16.1 14.9 0.011 16.1 14.9 6.2 5 1 0 5 5 5 0 EGF-like domain EGF_MSP1_1 PF12946.7 KFO97007.1 - 0.012 15.6 39.8 0.031 14.3 7.5 4.7 4 0 0 4 4 4 0 MSP1 EGF domain 1 hEGF PF12661.7 KFO97007.1 - 3.1 8.5 62.0 0.19 12.4 5.0 7.9 8 1 1 9 9 9 0 Human growth factor-like EGF Methyltransf_32 PF13679.6 KFO97008.1 - 8e-11 42.2 4.0 1.4e-09 38.1 4.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.14 KFO97008.1 - 1.2e-07 31.5 1.3 0.0095 15.5 0.0 2.8 1 1 1 2 2 2 2 Methyltransferase TRM13 Methyltransf_31 PF13847.6 KFO97008.1 - 4.6e-07 29.8 0.1 9.1e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 KFO97008.1 - 0.00015 21.2 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G GST_C_2 PF13410.6 KFO97008.1 - 0.0003 20.8 0.0 0.02 14.9 0.0 2.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Methyltransf_4 PF02390.17 KFO97008.1 - 0.0012 18.3 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KFO97008.1 - 0.0027 17.3 0.0 0.0051 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KFO97008.1 - 0.0078 16.9 0.1 0.018 15.8 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain GST_C_3 PF14497.6 KFO97008.1 - 0.016 15.4 0.0 0.048 13.9 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ubie_methyltran PF01209.18 KFO97008.1 - 0.023 14.0 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KFO97008.1 - 0.074 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_18 PF12847.7 KFO97008.1 - 0.19 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RhoGEF PF00621.20 KFO97010.1 - 1.2e-14 54.9 0.2 1.2e-14 54.9 0.2 2.7 2 1 0 2 2 2 1 RhoGEF domain BAR PF03114.18 KFO97010.1 - 2.4e-14 53.6 3.2 6e-14 52.3 3.2 1.7 1 0 0 1 1 1 1 BAR domain SH3_2 PF07653.17 KFO97010.1 - 1.3e-12 47.2 0.0 2.2e-05 24.0 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KFO97010.1 - 1.6e-09 37.2 0.5 6e-08 32.2 0.1 2.5 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFO97010.1 - 3.8e-09 36.3 0.2 1.2e-08 34.6 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.11 KFO97010.1 - 0.077 13.3 0.5 1.4 9.2 0.1 2.3 2 0 0 2 2 2 0 Bacterial SH3 domain RhoGEF PF00621.20 KFO97011.1 - 1.8e-19 70.7 0.2 2.4e-19 70.3 0.2 1.2 1 0 0 1 1 1 1 RhoGEF domain Tuberin PF03542.16 KFO97011.1 - 0.053 12.6 0.1 0.073 12.2 0.1 1.1 1 0 0 1 1 1 0 Tuberin Pyrophosphatase PF00719.19 KFO97012.1 - 3.7e-59 199.1 0.8 4.6e-59 198.8 0.8 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Tet_JBP PF12851.7 KFO97013.1 - 7.2e-137 456.2 4.6 7.2e-137 456.2 4.6 2.3 2 1 0 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily 7tm_1 PF00001.21 KFO97014.1 - 8.9e-58 195.7 20.3 1.2e-57 195.3 20.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFO97014.1 - 4.7e-11 42.6 20.3 6.2e-11 42.2 20.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFO97014.1 - 3.4e-05 23.7 19.3 0.00017 21.4 19.3 2.0 1 1 0 1 1 1 1 Olfactory receptor zf_C2H2_ZHX PF18387.1 KFO97014.1 - 0.076 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain adh_short_C2 PF13561.6 KFO97015.1 - 2.1e-62 210.7 0.3 2.5e-62 210.5 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFO97015.1 - 1.8e-47 161.4 0.6 2.2e-47 161.0 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFO97015.1 - 3.8e-06 26.9 0.3 6.7e-06 26.1 0.3 1.4 1 0 0 1 1 1 1 KR domain AlaDh_PNT_C PF01262.21 KFO97015.1 - 0.0001 21.6 0.4 0.00019 20.8 0.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 KFO97015.1 - 0.0018 18.6 0.1 0.0041 17.4 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KFO97015.1 - 0.0018 18.2 0.1 0.002 18.0 0.1 1.3 1 1 0 1 1 1 1 NAD(P)H-binding ADH_zinc_N PF00107.26 KFO97015.1 - 0.0066 16.4 0.2 0.012 15.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 KFO97015.1 - 0.011 15.3 0.1 0.026 14.1 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 KFO97015.1 - 0.019 14.9 0.2 0.042 13.7 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2325 PF10087.9 KFO97015.1 - 0.03 14.4 0.1 0.061 13.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) MA3 PF02847.17 KFO97016.1 - 1.4e-24 86.2 1.7 3.2e-24 85.1 1.7 1.6 1 0 0 1 1 1 1 MA3 domain CENP-B_dimeris PF09026.10 KFO97016.1 - 0.018 15.4 6.7 0.018 15.4 6.7 4.2 4 0 0 4 4 4 0 Centromere protein B dimerisation domain zf-met PF12874.7 KFO97017.1 - 8.7e-29 99.0 25.2 1.2e-07 31.8 1.9 4.4 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFO97017.1 - 2.2e-22 78.8 20.7 3e-06 27.4 3.0 4.3 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFO97017.1 - 8.8e-10 38.8 9.8 0.15 12.4 0.4 4.2 4 0 0 4 4 4 4 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.12 KFO97017.1 - 2e-09 37.0 12.2 0.015 15.0 0.0 4.3 4 0 0 4 4 4 4 U1 zinc finger AKAP95 PF04988.12 KFO97017.1 - 1.3e-06 28.7 6.7 0.19 12.0 0.1 4.2 4 0 0 4 4 4 2 A-kinase anchoring protein 95 (AKAP95) zf-DBF PF07535.12 KFO97017.1 - 0.0076 16.3 13.3 0.19 11.9 0.8 4.3 4 0 0 4 4 4 1 DBF zinc finger DUF3449 PF11931.8 KFO97017.1 - 0.0095 15.7 1.2 8.5 6.1 0.1 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) zf-C2H2 PF00096.26 KFO97017.1 - 0.017 15.6 12.4 5.1 7.8 1.4 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type UPF0728 PF15092.6 KFO97017.1 - 0.09 12.6 0.1 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0728 zf-C2H2_9 PF16293.5 KFO97017.1 - 0.23 11.3 8.4 29 4.6 0.3 4.2 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_4 PF13894.6 KFO97017.1 - 0.25 12.3 9.9 11 7.2 0.4 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zinc_ribbon_15 PF17032.5 KFO97017.1 - 0.31 11.8 8.1 5.7 7.8 0.2 3.6 3 1 0 3 3 3 0 zinc-ribbon family zf-piccolo PF05715.13 KFO97017.1 - 0.39 10.9 6.7 21 5.4 0.1 4.1 4 0 0 4 4 4 0 Piccolo Zn-finger Actin_micro PF17003.5 KFO97017.1 - 0.45 9.6 12.2 2 7.5 0.2 3.6 3 1 0 3 3 3 0 Putative actin-like family zf-RING_7 PF02591.15 KFO97017.1 - 0.58 10.4 3.3 8.2 6.7 0.1 3.8 4 0 0 4 4 4 0 C4-type zinc ribbon domain C1_1 PF00130.22 KFO97017.1 - 0.8 9.6 4.2 20 5.1 0.0 3.8 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) IBR PF01485.21 KFO97017.1 - 1.7 8.9 6.1 8.2 6.7 0.0 3.4 3 1 0 3 3 3 0 IBR domain, a half RING-finger domain zf_C2H2_ZHX PF18387.1 KFO97017.1 - 2.1 8.1 10.0 1.3 8.7 0.4 2.9 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain CRAL_TRIO_2 PF13716.6 KFO97019.1 - 1.1e-07 32.1 0.1 2.2e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Spectrin PF00435.21 KFO97019.1 - 0.0002 21.8 26.2 0.00034 21.0 0.4 4.7 4 1 1 5 5 5 2 Spectrin repeat MatP PF06303.12 KFO97019.1 - 0.061 13.9 3.1 1 10.0 0.9 2.9 2 0 0 2 2 2 0 MatP N-terminal domain Spectrin PF00435.21 KFO97020.1 - 0.18 12.3 14.4 2.2 8.8 3.5 3.2 3 0 0 3 3 3 0 Spectrin repeat Sec34 PF04136.15 KFO97021.1 - 0.012 15.4 0.6 3.3 7.6 0.1 2.2 1 1 1 2 2 2 0 Sec34-like family SesA PF17107.5 KFO97021.1 - 0.027 14.7 0.0 0.047 13.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Spectrin PF00435.21 KFO97021.1 - 0.043 14.3 4.1 0.52 10.8 0.9 2.7 2 1 0 2 2 2 0 Spectrin repeat Phage_Gp23 PF10669.9 KFO97021.1 - 0.084 13.2 0.9 0.16 12.3 0.1 1.8 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) I-set PF07679.16 KFO97022.1 - 4.7e-12 45.8 0.0 6.3e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO97022.1 - 6.1e-07 29.9 0.0 9.5e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFO97022.1 - 3.5e-05 23.9 0.0 4.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 KFO97022.1 - 0.00027 20.5 0.0 0.00045 19.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFO97022.1 - 0.00035 20.8 0.0 0.00058 20.1 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFO97022.1 - 0.0018 18.3 0.0 0.0036 17.3 0.0 1.4 1 0 0 1 1 1 1 Izumo-like Immunoglobulin domain V-set PF07686.17 KFO97022.1 - 0.0025 18.0 0.0 0.0034 17.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain fn3 PF00041.21 KFO97023.1 - 1.4e-99 326.6 0.3 2.1e-17 63.2 0.0 7.5 8 0 0 8 8 8 7 Fibronectin type III domain I-set PF07679.16 KFO97023.1 - 1.3e-24 86.1 1.5 2.2e-12 46.9 0.1 3.4 4 0 0 4 4 4 2 Immunoglobulin I-set domain Pur_ac_phosph_N PF16656.5 KFO97023.1 - 9.6e-21 74.2 0.0 0.002 18.7 0.0 7.6 7 1 0 7 7 7 5 Purple acid Phosphatase, N-terminal domain Ig_3 PF13927.6 KFO97023.1 - 1.1e-15 57.9 0.0 1.1e-06 29.1 0.0 3.0 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFO97023.1 - 3.2e-09 36.8 0.2 0.00062 19.9 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain fn3_4 PF16794.5 KFO97023.1 - 2.7e-06 27.3 0.0 0.93 9.4 0.0 6.8 8 2 0 8 8 8 1 Fibronectin-III type domain PhoD_N PF16655.5 KFO97023.1 - 5.3e-06 26.9 0.0 31 5.2 0.0 5.9 7 0 0 7 7 7 0 PhoD-like phosphatase, N-terminal domain Tissue_fac PF01108.17 KFO97023.1 - 1.2e-05 25.1 0.0 0.99 9.3 0.0 6.2 7 0 0 7 7 7 1 Tissue factor DUF2369 PF10179.9 KFO97023.1 - 0.00084 19.7 0.0 16 6.0 0.0 4.9 5 0 0 5 5 5 0 Uncharacterised conserved protein (DUF2369) V-set PF07686.17 KFO97023.1 - 0.003 17.7 0.0 0.8 9.9 0.0 3.2 2 1 0 2 2 2 1 Immunoglobulin V-set domain Reeler PF02014.16 KFO97023.1 - 0.0056 17.4 0.2 73 4.1 0.0 4.7 4 0 0 4 4 4 0 Reeler domain Y_Y_Y PF07495.13 KFO97023.1 - 0.016 15.2 0.0 9 6.3 0.0 4.6 5 0 0 5 5 5 0 Y_Y_Y domain MIB_HERC2 PF06701.13 KFO97023.1 - 0.075 13.3 3.7 15 5.9 0.1 4.0 4 0 0 4 4 4 0 Mib_herc2 DUF4945 PF16303.5 KFO97023.1 - 0.098 12.6 1.5 83 3.1 0.0 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF4945) fn3 PF00041.21 KFO97024.1 - 2.5e-104 341.8 4.5 2.7e-21 75.7 0.1 7.3 7 0 0 7 7 7 7 Fibronectin type III domain I-set PF07679.16 KFO97024.1 - 9.5e-35 118.6 1.1 6.6e-15 54.9 0.0 4.5 5 0 0 5 5 5 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO97024.1 - 1.4e-19 70.5 0.0 3.5e-08 33.9 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFO97024.1 - 4.2e-18 65.7 6.9 0.0039 17.7 0.1 8.0 8 0 0 8 8 8 5 Purple acid Phosphatase, N-terminal domain ig PF00047.25 KFO97024.1 - 1.8e-15 56.9 0.0 3e-06 27.3 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFO97024.1 - 2e-10 40.8 0.0 0.00069 19.9 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain Tissue_fac PF01108.17 KFO97024.1 - 1.2e-08 34.8 0.0 0.001 18.9 0.0 5.1 5 0 0 5 5 5 1 Tissue factor SusE PF14292.6 KFO97024.1 - 4.8e-06 26.8 0.1 1.9 8.8 0.0 4.4 4 0 0 4 4 4 2 SusE outer membrane protein fn3_2 PF16893.5 KFO97024.1 - 2e-05 24.6 0.0 4.2 7.6 0.0 5.1 5 0 0 5 5 5 1 Fibronectin type III domain PhoD_N PF16655.5 KFO97024.1 - 0.0011 19.5 0.2 26 5.4 0.0 4.5 4 1 0 4 4 4 0 PhoD-like phosphatase, N-terminal domain Receptor_2B4 PF11465.8 KFO97024.1 - 0.011 15.9 0.7 9.3 6.5 0.0 4.2 4 1 1 5 5 5 0 Natural killer cell receptor 2B4 V-set PF07686.17 KFO97024.1 - 0.026 14.7 0.1 16 5.7 0.1 3.6 2 2 0 2 2 2 0 Immunoglobulin V-set domain Lipocalin_7 PF14651.6 KFO97024.1 - 0.032 14.1 0.0 4.6 7.2 0.0 3.1 3 0 0 3 3 3 0 Lipocalin / cytosolic fatty-acid binding protein family Reeler PF02014.16 KFO97024.1 - 0.054 14.2 0.0 54 4.6 0.0 4.5 5 0 0 5 5 5 0 Reeler domain SLAM PF06214.11 KFO97024.1 - 0.069 13.2 0.0 0.64 10.0 0.0 2.2 2 0 0 2 2 2 0 Signaling lymphocytic activation molecule (SLAM) protein C2-set_2 PF08205.12 KFO97024.1 - 0.096 12.8 0.0 0.91 9.6 0.0 2.3 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain I-set PF07679.16 KFO97025.1 - 9.2e-09 35.3 0.0 9.4e-09 35.2 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO97025.1 - 2.6e-05 24.7 0.0 2.7e-05 24.7 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFO97025.1 - 0.027 14.8 0.0 0.03 14.7 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain C2-set_2 PF08205.12 KFO97025.1 - 0.17 11.9 0.1 0.18 11.9 0.1 1.2 1 1 0 1 1 1 0 CD80-like C2-set immunoglobulin domain I-set PF07679.16 KFO97026.1 - 8.4e-08 32.2 0.0 8.8e-08 32.1 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO97026.1 - 7.2e-06 26.5 0.0 7.3e-06 26.5 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFO97026.1 - 0.019 15.3 0.0 0.022 15.1 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain C2-set_2 PF08205.12 KFO97026.1 - 0.15 12.2 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain I-set PF07679.16 KFO97027.1 - 6e-07 29.4 0.0 6.5e-07 29.3 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO97027.1 - 2.4e-06 28.1 0.0 2.4e-06 28.0 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFO97027.1 - 0.14 12.5 0.0 0.16 12.3 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFO97028.1 - 3e-07 30.4 0.0 3.2e-07 30.3 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO97028.1 - 3.2e-05 24.4 0.0 3.4e-05 24.4 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFO97029.1 - 5.2e-07 29.7 0.0 5.3e-07 29.6 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO97029.1 - 1.7e-05 25.4 0.0 1.7e-05 25.3 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFO97029.1 - 0.0014 18.8 0.0 0.0017 18.4 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFO97030.1 - 7.1e-09 35.6 0.0 7.4e-09 35.6 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO97030.1 - 1.6e-06 28.6 0.0 1.6e-06 28.6 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFO97030.1 - 0.0072 16.6 0.0 0.0076 16.6 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFO97030.1 - 0.01 16.0 0.0 0.012 15.8 0.0 1.0 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFO97031.1 - 1.3e-09 38.0 0.0 1.3e-09 37.9 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO97031.1 - 5.7e-08 33.3 0.1 5.8e-08 33.2 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFO97031.1 - 0.00024 21.2 0.1 0.00027 21.0 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFO97031.1 - 0.0018 18.6 0.0 0.0019 18.5 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFO97031.1 - 0.0039 17.3 0.0 0.004 17.3 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFO97032.1 - 4.1e-06 26.8 0.0 4.3e-06 26.7 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO97032.1 - 0.00058 20.4 0.0 0.00061 20.3 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFO97033.1 - 3.2e-07 30.3 0.0 3.4e-07 30.2 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO97033.1 - 3.4e-07 30.8 0.0 3.6e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFO97033.1 - 0.011 16.1 0.0 0.011 16.0 0.0 1.0 1 0 0 1 1 1 0 Immunoglobulin domain C2-set_2 PF08205.12 KFO97033.1 - 0.068 13.2 0.0 0.073 13.1 0.0 1.1 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain CRF1 PF10380.9 KFO97033.1 - 0.092 13.1 0.0 0.095 13.1 0.0 1.0 1 0 0 1 1 1 0 Transcription factor CRF1 ig PF00047.25 KFO97033.1 - 0.11 12.7 0.0 0.14 12.3 0.0 1.2 1 1 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFO97034.1 - 2.1e-77 255.3 8.9 3e-26 91.3 0.1 5.3 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO97034.1 - 1.9e-52 175.8 9.0 3.4e-15 56.4 0.1 5.8 5 0 0 5 5 5 5 Immunoglobulin domain Ig_2 PF13895.6 KFO97034.1 - 2.3e-30 104.7 7.0 7.2e-09 35.9 0.1 5.5 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 KFO97034.1 - 3.8e-30 103.9 8.0 2.9e-13 49.8 0.1 5.4 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.17 KFO97034.1 - 3.9e-21 75.3 14.5 5.5e-05 23.3 0.3 8.3 5 3 0 5 5 5 5 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFO97034.1 - 4.1e-10 39.6 1.4 0.00099 19.1 0.1 5.5 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.8 KFO97034.1 - 1.9e-09 37.7 2.3 0.29 11.4 0.1 4.6 4 1 0 4 4 4 3 Natural killer cell receptor 2B4 C1-set PF07654.15 KFO97034.1 - 1.3e-06 28.6 2.7 0.0083 16.5 0.0 5.2 5 0 0 5 5 5 1 Immunoglobulin C1-set domain Ig_4 PF16680.5 KFO97034.1 - 5.1e-06 26.7 1.9 0.22 11.8 0.1 4.3 4 0 0 4 4 3 2 T-cell surface glycoprotein CD3 delta chain PKD_3 PF16820.5 KFO97034.1 - 0.0018 18.0 0.1 4.3 7.2 0.0 4.3 4 0 0 4 4 4 1 PKD-like domain MetRS-N PF09635.10 KFO97034.1 - 0.1 13.2 0.3 1.2 9.7 0.0 2.8 3 0 0 3 3 3 0 MetRS-N binding domain FAD_binding_6 PF00970.24 KFO97034.1 - 0.12 12.7 0.1 0.59 10.5 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Thioredoxin_14 PF18402.1 KFO97034.1 - 0.48 10.3 4.8 0.79 9.6 1.1 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain PH PF00169.29 KFO97035.1 - 7.3e-10 39.3 0.0 1.6e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFO97035.1 - 3.1e-05 24.2 0.0 8.7e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 KFO97035.1 - 4.6e-05 23.8 0.3 0.00034 21.0 0.2 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain Muted PF14942.6 KFO97035.1 - 0.0063 16.9 0.4 0.012 15.9 0.4 1.4 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein DUF5327 PF17261.2 KFO97035.1 - 0.069 13.9 0.8 0.15 12.8 0.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5327) Cmc1 PF08583.10 KFO97035.1 - 0.086 12.9 1.4 4.5 7.4 0.1 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like PH_6 PF15406.6 KFO97035.1 - 0.13 12.6 0.0 0.47 10.8 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain FKBP_C PF00254.28 KFO97036.1 - 9.6e-31 106.0 0.0 1.5e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_6 PF13405.6 KFO97036.1 - 2.5e-07 30.1 1.9 0.022 14.7 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KFO97036.1 - 8.1e-07 29.4 0.8 1.5e-06 28.6 0.8 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFO97036.1 - 9.4e-07 28.0 1.4 0.006 16.0 0.2 2.4 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KFO97036.1 - 3.9e-06 26.1 1.3 0.0049 16.3 0.2 2.6 2 0 0 2 2 2 2 EF hand Gasdermin PF04598.12 KFO97037.1 - 1.2e-16 60.9 0.0 1.4e-16 60.7 0.0 1.0 1 0 0 1 1 1 1 Gasdermin pore forming domain DUF4663 PF15668.5 KFO97037.1 - 0.0045 16.1 0.0 0.0049 16.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4663) Oxysterol_BP PF01237.18 KFO97038.1 - 9e-129 429.5 0.9 9e-129 429.5 0.9 2.2 2 1 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.6 KFO97038.1 - 8.1e-13 48.5 0.2 1.8e-12 47.4 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFO97038.1 - 1.4e-07 31.9 0.6 4.4e-07 30.4 0.6 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFO97038.1 - 0.046 14.1 2.6 3.1 8.2 2.6 2.9 1 1 0 1 1 1 0 Pleckstrin homology domain RRM_1 PF00076.22 KFO97039.1 - 8.4e-45 150.5 0.0 1.1e-13 50.7 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFO97039.1 - 1.9e-05 24.6 0.0 0.18 11.8 0.0 3.4 2 1 1 3 3 3 1 RNA binding motif RRM_occluded PF16842.5 KFO97039.1 - 0.00026 20.8 0.0 0.13 12.2 0.0 3.4 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KFO97039.1 - 0.00047 19.7 0.0 1.8 8.2 0.0 3.6 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 KFO97039.1 - 0.00061 19.8 0.0 0.43 10.6 0.0 2.9 2 0 0 2 2 2 2 RNA binding domain Nup35_RRM_2 PF14605.6 KFO97039.1 - 0.001 19.0 0.1 3.5 7.7 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif TPR_1 PF00515.28 KFO97040.1 - 3.9e-12 45.4 8.3 0.049 13.5 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFO97040.1 - 3.7e-11 42.3 10.3 0.06 13.5 0.0 7.3 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFO97040.1 - 1.9e-10 41.1 0.0 0.0057 17.1 0.0 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFO97040.1 - 1.3e-09 38.2 0.8 0.23 11.8 0.0 6.5 4 2 1 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO97040.1 - 4.1e-06 26.9 2.8 0.0025 18.0 0.1 4.1 6 1 1 7 7 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KFO97040.1 - 4.9e-06 26.2 0.3 0.054 13.4 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFO97040.1 - 1.7e-05 24.7 7.6 0.28 11.5 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat DUF285 PF03382.14 KFO97040.1 - 0.0011 18.7 3.6 0.0024 17.6 1.3 2.1 1 1 1 2 2 2 1 Mycoplasma protein of unknown function, DUF285 TPR_7 PF13176.6 KFO97040.1 - 0.0033 17.3 1.0 12 6.2 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3808 PF10300.9 KFO97040.1 - 0.0063 15.3 9.2 0.53 8.9 0.6 3.4 1 1 2 3 3 3 2 Protein of unknown function (DUF3808) TPR_16 PF13432.6 KFO97040.1 - 0.0084 16.7 0.8 6.8 7.4 0.0 4.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFO97040.1 - 0.01 16.6 0.2 1.3e+02 3.8 0.0 5.3 5 2 1 6 6 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFO97040.1 - 0.042 13.5 0.1 3.2 7.5 0.0 2.8 2 0 0 2 2 2 0 TPR repeat TPR_21 PF09976.9 KFO97040.1 - 0.054 13.2 2.2 0.14 11.8 0.2 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain DASH_Dad2 PF08654.10 KFO97040.1 - 0.1 13.0 0.6 0.43 11.0 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad2 SNAP PF14938.6 KFO97040.1 - 0.11 11.9 6.1 1.3 8.4 0.5 2.5 1 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP Sec23_helical PF04815.15 KFO97040.1 - 0.14 12.0 0.1 1.7 8.5 0.0 2.7 2 0 0 2 2 2 0 Sec23/Sec24 helical domain RPN6_N PF18055.1 KFO97040.1 - 1.1 9.6 4.5 13 6.2 0.3 2.9 2 1 1 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_6 PF13174.6 KFO97040.1 - 1.6 9.6 3.8 1.5e+02 3.3 0.0 4.6 6 0 0 6 6 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 KFO97040.1 - 2.4 8.3 7.3 8.9 6.4 0.0 3.9 5 0 0 5 5 3 0 Tetratricopeptide repeat FAD-oxidase_C PF02913.19 KFO97041.1 - 5.2e-58 196.6 0.0 6.9e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KFO97041.1 - 1.6e-37 128.3 0.0 9.4e-37 125.8 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KFO97041.1 - 0.085 13.0 0.0 0.27 11.4 0.0 1.8 1 0 0 1 1 1 0 Berberine and berberine like Tom37 PF10568.9 KFO97044.1 - 1.6e-30 106.0 0.1 5.5e-30 104.3 0.0 1.8 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KFO97044.1 - 5.1e-25 88.1 0.0 1.2e-24 86.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KFO97044.1 - 3.7e-24 84.3 0.1 1.1e-23 82.8 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFO97044.1 - 1.4e-06 28.2 0.0 3.7e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFO97044.1 - 0.05 13.8 0.1 0.17 12.1 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Homeodomain PF00046.29 KFO97045.1 - 5e-22 77.5 9.1 5e-22 77.5 9.1 1.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KFO97045.1 - 0.067 13.1 0.9 0.14 12.1 0.9 1.5 1 0 0 1 1 1 0 Homeobox KN domain DUF2209 PF09974.9 KFO97045.1 - 0.076 13.4 0.1 0.11 12.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Homeodomain PF00046.29 KFO97046.1 - 1.5e-20 72.8 9.6 1.7e-20 72.6 6.1 2.3 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KFO97046.1 - 0.013 15.4 1.8 0.031 14.2 0.3 2.4 2 0 0 2 2 2 0 Homeobox KN domain IL8 PF00048.20 KFO97046.1 - 0.028 14.6 0.5 0.08 13.1 0.5 1.8 1 0 0 1 1 1 0 Small cytokines (intecrine/chemokine), interleukin-8 like Histone PF00125.24 KFO97046.1 - 0.46 10.8 4.8 1.4 9.3 0.0 2.9 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 DUF3528 PF12045.8 KFO97047.1 - 2e-60 203.5 0.5 3.5e-60 202.7 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3528) Homeodomain PF00046.29 KFO97047.1 - 2.2e-20 72.3 8.3 4e-20 71.4 8.3 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO97047.1 - 0.023 14.6 0.6 0.069 13.1 0.6 1.8 1 0 0 1 1 1 0 Homeobox KN domain DUF3544 PF12064.8 KFO97047.1 - 0.097 12.9 3.7 0.15 12.3 3.7 1.2 1 0 0 1 1 1 0 Protein kinase C-binding protein 1 Homeodomain PF00046.29 KFO97048.1 - 1.9e-20 72.4 10.8 2.1e-20 72.3 10.8 1.0 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 KFO97048.1 - 0.0029 17.1 0.3 0.004 16.6 0.3 1.2 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 KFO97048.1 - 0.01 15.7 5.3 0.026 14.4 5.3 1.9 1 1 0 1 1 1 0 Homeobox KN domain Homeodomain PF00046.29 KFO97049.1 - 3.5e-19 68.4 6.1 4.2e-19 68.2 6.1 1.1 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO97049.1 - 0.00024 20.9 3.4 0.00026 20.8 2.3 1.6 1 1 0 1 1 1 1 Homeobox KN domain DUF1510 PF07423.11 KFO97049.1 - 0.031 14.4 0.1 0.034 14.3 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1510) HTH_23 PF13384.6 KFO97049.1 - 0.049 13.5 0.1 0.071 12.9 0.1 1.3 1 0 0 1 1 1 0 Homeodomain-like domain Homeodomain PF00046.29 KFO97050.1 - 0.0019 18.0 2.6 0.0039 17.0 2.6 1.5 1 0 0 1 1 1 1 Homeodomain zinc_ribbon_10 PF10058.9 KFO97051.1 - 1.7e-21 75.7 0.3 2.5e-21 75.1 0.3 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein 7tm_7 PF08395.12 KFO97051.1 - 0.0015 17.8 0.3 0.0018 17.5 0.3 1.1 1 0 0 1 1 1 1 7tm Chemosensory receptor DUF4153 PF13687.6 KFO97051.1 - 0.0039 16.8 0.2 0.0065 16.1 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4153) DUF2207 PF09972.9 KFO97051.1 - 0.011 14.5 0.2 0.014 14.2 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Granin PF01271.17 KFO97051.1 - 0.016 14.2 0.6 0.016 14.2 0.6 1.6 2 0 0 2 2 2 0 Granin (chromogranin or secretogranin) ATP-synt_C PF00137.21 KFO97052.1 - 1.3e-11 44.7 12.4 1.8e-11 44.2 12.4 1.2 1 0 0 1 1 1 1 ATP synthase subunit C Phage_holin_3_6 PF07332.11 KFO97052.1 - 8 6.5 8.9 15 5.6 8.9 1.5 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III bZIP_1 PF00170.21 KFO97053.1 - 3.2e-12 46.4 7.0 5e-12 45.7 7.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFO97053.1 - 3.7e-09 36.5 7.7 9.3e-09 35.2 7.7 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFO97053.1 - 0.0046 17.5 7.7 0.011 16.2 7.7 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor zf-C2H2 PF00096.26 KFO97053.1 - 0.027 14.9 1.5 0.054 14.0 1.5 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type RhoGAP PF00620.27 KFO97054.1 - 5e-50 169.3 0.0 8.7e-50 168.5 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 KFO97054.1 - 4e-16 58.6 7.5 7e-16 57.9 7.5 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH2 PF00017.24 KFO97054.1 - 4.4e-14 52.3 0.1 1e-13 51.2 0.1 1.6 1 0 0 1 1 1 1 SH2 domain FYVE_2 PF02318.16 KFO97054.1 - 0.042 14.1 2.0 0.08 13.2 2.0 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger PHD_2 PF13831.6 KFO97054.1 - 0.068 12.7 1.6 0.15 11.6 1.6 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 KFO97054.1 - 0.28 11.5 5.1 0.59 10.5 5.1 1.5 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 KFO97054.1 - 3 7.8 7.6 6 6.8 7.6 1.5 1 0 0 1 1 1 0 PHD-finger Neur_chan_LBD PF02931.23 KFO97055.1 - 4.6e-71 238.7 1.7 6.1e-71 238.3 1.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFO97055.1 - 1.8e-67 227.9 10.8 7.3e-52 176.8 8.6 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Mem_trans PF03547.18 KFO97056.1 - 9.7e-19 67.0 21.7 1.8e-13 49.7 6.4 3.0 2 2 1 3 3 3 2 Membrane transport protein DEP PF00610.21 KFO97056.1 - 1.9e-12 47.1 0.0 4.1e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF3328 PF11807.8 KFO97056.1 - 0.35 10.6 1.9 44 3.8 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3328) Peptidase_C69 PF03577.15 KFO97057.1 - 1.9e-08 33.7 0.1 2.7e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase family C69 AAT PF03417.16 KFO97057.1 - 0.0011 18.6 0.0 0.01 15.6 0.0 2.3 2 1 0 2 2 2 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Ca_bind_SSO6904 PF18249.1 KFO97057.1 - 0.055 13.8 0.0 11 6.4 0.0 2.6 2 0 0 2 2 2 0 Calcium binding protein SSO6904 RTP PF02334.16 KFO97057.1 - 0.059 14.0 0.9 0.15 12.7 0.9 1.6 1 1 0 1 1 1 0 Replication terminator protein YchF-GTPase_C PF06071.13 KFO97058.1 - 6.2e-42 141.7 0.4 2.2e-41 139.9 0.4 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KFO97058.1 - 1.7e-23 82.9 0.0 5.2e-23 81.3 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFO97058.1 - 1.9e-07 30.7 0.0 4.3e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 KFO97058.1 - 0.0036 17.3 0.0 0.0082 16.2 0.0 1.5 1 0 0 1 1 1 1 TGS domain MeaB PF03308.16 KFO97058.1 - 0.006 15.6 0.0 0.015 14.3 0.0 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 KFO97058.1 - 0.012 15.8 0.0 1.4 9.2 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KFO97058.1 - 0.037 14.6 0.0 0.77 10.3 0.0 2.7 2 1 1 3 3 3 0 AAA domain Dynamin_N PF00350.23 KFO97058.1 - 0.07 13.2 0.0 9.2 6.3 0.0 2.6 2 0 0 2 2 2 0 Dynamin family zf-C2H2 PF00096.26 KFO97059.1 - 2e-05 24.8 2.2 2e-05 24.8 2.2 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO97059.1 - 0.00083 20.0 1.8 0.00083 20.0 1.8 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFO97059.1 - 0.0048 17.3 1.1 0.0048 17.3 1.1 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KFO97059.1 - 0.07 13.1 1.4 0.15 12.1 1.4 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zinc_ribbon_9 PF14369.6 KFO97059.1 - 0.23 11.7 1.0 11 6.4 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon zf-C2H2_9 PF16293.5 KFO97059.1 - 0.31 10.9 0.7 0.75 9.7 0.3 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 KFO97059.1 - 0.8 10.0 4.1 1.1 9.6 0.5 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Pkinase_Tyr PF07714.17 KFO97060.1 - 2.3e-63 213.9 0.0 4.4e-63 213.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO97060.1 - 5.2e-56 189.9 0.0 1e-55 188.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain SAM_2 PF07647.17 KFO97060.1 - 1.5e-09 37.8 0.1 8.6e-09 35.4 0.1 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFO97060.1 - 2.5e-09 37.4 4.0 5e-09 36.5 0.3 3.2 4 0 0 4 4 4 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFO97060.1 - 0.0061 16.5 0.7 0.019 14.9 0.1 2.1 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain SAM_4 PF18017.1 KFO97060.1 - 0.051 13.6 0.0 0.22 11.5 0.0 2.1 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF3552 PF12072.8 KFO97060.1 - 1 8.8 4.0 1.7 8.0 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) APG6_N PF17675.1 KFO97060.1 - 1.7 9.2 8.1 0.15 12.6 3.2 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region RasGEF PF00617.19 KFO97061.1 - 3.1e-52 177.3 1.8 3.1e-52 177.3 1.8 1.8 2 0 0 2 2 2 1 RasGEF domain cNMP_binding PF00027.29 KFO97061.1 - 2.9e-36 123.4 0.0 4.6e-16 58.7 0.0 3.6 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain DEP PF00610.21 KFO97061.1 - 2.2e-22 78.9 2.5 1e-21 76.7 1.3 2.5 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RasGEF_N PF00618.20 KFO97061.1 - 5.6e-12 45.8 0.0 1.7e-11 44.3 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif RA PF00788.23 KFO97061.1 - 0.039 14.6 0.0 0.14 12.9 0.0 1.9 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain BLOC1_2 PF10046.9 KFO97061.1 - 0.42 10.9 2.7 5.4 7.4 0.7 2.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PDZ_5 PF17817.1 KFO97062.1 - 1.2e-27 96.0 3.7 1.2e-27 96.0 3.7 2.6 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 KFO97062.1 - 1.6e-13 50.8 2.9 3.1e-13 49.9 1.9 2.1 2 0 0 2 2 2 1 PDZ domain SAM_2 PF07647.17 KFO97062.1 - 8.8e-09 35.3 0.5 2.1e-08 34.2 0.5 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFO97062.1 - 3e-07 30.8 1.1 3e-07 30.8 1.1 2.4 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) PDZ_6 PF17820.1 KFO97062.1 - 3.9e-05 23.4 0.5 0.0003 20.5 0.1 2.7 3 0 0 3 3 3 1 PDZ domain SAM_PNT PF02198.16 KFO97062.1 - 0.00031 20.6 1.7 0.00069 19.5 1.7 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PsbU PF06514.11 KFO97062.1 - 0.012 15.6 0.1 0.068 13.2 0.1 2.3 1 0 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) PDZ_2 PF13180.6 KFO97062.1 - 0.016 15.5 0.3 0.05 13.9 0.3 1.8 1 0 0 1 1 1 0 PDZ domain DUF2407_C PF13373.6 KFO97062.1 - 0.17 12.1 4.2 0.66 10.1 4.2 2.1 1 0 0 1 1 1 0 DUF2407 C-terminal domain Pox_A_type_inc PF04508.12 KFO97062.1 - 0.25 11.3 1.8 0.66 9.9 0.4 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF745 PF05335.13 KFO97062.1 - 0.42 10.3 13.4 0.81 9.4 12.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF745) DUF3450 PF11932.8 KFO97062.1 - 0.46 9.7 16.5 1.6 8.0 16.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Atg14 PF10186.9 KFO97062.1 - 1.1 8.3 20.9 0.18 10.9 15.7 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 BCDHK_Adom3 PF10436.9 KFO97063.1 - 1.4e-48 164.8 0.0 2.3e-48 164.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KFO97063.1 - 1.1e-14 54.9 0.0 2.1e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFO97063.1 - 0.00052 19.8 0.0 0.00091 19.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KFO97063.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Integrin_alpha2 PF08441.12 KFO97064.1 - 2.4e-128 429.0 2.4 3e-128 428.6 2.4 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 KFO97064.1 - 9.2e-19 67.2 25.2 1.4e-09 37.9 7.1 4.4 4 0 0 4 4 4 3 FG-GAP repeat VCBS PF13517.6 KFO97064.1 - 3.6e-15 56.3 10.6 3.8e-11 43.4 2.6 3.1 1 1 2 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 KFO97064.1 - 0.31 11.3 13.3 3.3 8.0 3.2 3.9 3 0 0 3 3 3 0 FG-GAP repeat Homeodomain PF00046.29 KFO97065.1 - 1.3e-20 73.0 3.2 2.2e-20 72.2 3.2 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO97065.1 - 0.0045 16.8 0.7 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.8 KFO97065.1 - 0.074 12.5 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez YdaS_antitoxin PF15943.5 KFO97065.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Peptidase_M24 PF00557.24 KFO97066.1 - 1.1e-54 185.3 0.0 1.3e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Hat1_N PF10394.9 KFO97067.1 - 1.5e-36 126.0 1.1 3e-36 125.1 0.9 1.6 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 KFO97067.1 - 0.021 15.1 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFO97067.1 - 0.029 14.3 0.0 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFO97067.1 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Mito_carr PF00153.27 KFO97068.1 - 3.9e-73 241.5 2.1 8.4e-26 89.7 0.0 3.6 4 0 0 4 4 4 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KFO97068.1 - 2.6e-12 45.3 1.4 0.016 14.7 0.1 5.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFO97068.1 - 1.5e-11 43.3 2.4 0.0095 15.8 0.1 5.6 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 KFO97068.1 - 5.2e-10 39.6 0.7 0.0028 18.0 0.0 4.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 KFO97068.1 - 1.9e-05 24.4 0.1 0.012 15.4 0.0 3.8 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 KFO97068.1 - 7.7e-05 22.0 0.6 2.3 7.9 0.0 4.0 4 0 0 4 4 4 2 EF hand Dynein_IC2 PF11540.8 KFO97069.1 - 3.4e-15 55.7 0.6 7.2e-15 54.6 0.6 1.6 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 WD40 PF00400.32 KFO97069.1 - 1.6e-07 31.9 10.3 0.096 13.6 0.3 7.1 7 0 0 7 7 7 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO97069.1 - 0.0011 19.2 0.0 0.028 14.7 0.0 3.2 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain MAT1 PF06391.13 KFO97069.1 - 0.15 11.9 15.8 1.7 8.4 7.5 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Cytochrom_B561 PF03188.16 KFO97070.1 - 3e-39 134.3 8.2 3e-39 134.3 8.2 1.4 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Ferric_reduct PF01794.19 KFO97070.1 - 0.34 11.0 8.5 0.082 13.0 2.8 2.1 1 1 1 2 2 2 0 Ferric reductase like transmembrane component DUF373 PF04123.13 KFO97070.1 - 1.8 7.9 6.6 3.4 7.0 5.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF4231 PF14015.6 KFO97070.1 - 7.3 7.1 10.0 31 5.1 4.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) DCAF17 PF15802.5 KFO97071.1 - 1e-220 733.5 0.3 1.1e-220 733.3 0.3 1.0 1 0 0 1 1 1 1 DDB1- and CUL4-associated factor 17 Methyltransf_25 PF13649.6 KFO97072.1 - 7.8e-13 49.0 0.1 2e-12 47.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFO97072.1 - 1.3e-11 44.6 0.0 2.3e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFO97072.1 - 2.2e-11 44.4 0.0 5.6e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFO97072.1 - 2.8e-11 43.9 0.0 5.7e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFO97072.1 - 2.1e-05 24.3 0.0 5.2e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 KFO97072.1 - 0.022 15.8 0.0 0.062 14.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Gal-bind_lectin PF00337.22 KFO97072.1 - 0.026 14.1 0.1 0.053 13.1 0.1 1.5 1 0 0 1 1 1 0 Galactoside-binding lectin CheR PF01739.18 KFO97072.1 - 0.036 13.5 0.0 0.61 9.5 0.0 2.2 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain NodS PF05401.11 KFO97072.1 - 0.047 13.3 0.0 0.098 12.3 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) MMR1 PF08505.10 KFO97072.1 - 0.21 11.8 4.7 0.3 11.3 4.7 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Pkinase PF00069.25 KFO97073.1 - 1.5e-61 208.1 0.0 1.5e-61 208.1 0.0 1.9 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO97073.1 - 2.3e-34 118.8 0.0 5.4e-34 117.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Vir_act_alpha_C PF10400.9 KFO97073.1 - 3.5 8.4 16.9 2.4 8.9 3.5 3.7 3 1 0 3 3 3 0 Virulence activator alpha C-term GRASP55_65 PF04495.14 KFO97074.1 - 2e-69 232.3 0.0 7.8e-54 181.7 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KFO97074.1 - 2e-08 34.0 0.0 0.0032 17.3 0.0 2.8 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFO97074.1 - 1.3e-06 28.7 0.0 0.044 14.1 0.0 2.7 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 KFO97074.1 - 0.17 12.3 0.0 32 5.0 0.0 2.4 2 0 0 2 2 2 0 PDZ domain Pyridoxal_deC PF00282.19 KFO97075.1 - 4.8e-152 506.0 0.0 5.6e-152 505.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KFO97075.1 - 9.1e-06 25.2 0.0 1.7e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KFO97075.1 - 9.4e-06 24.8 0.0 0.00012 21.2 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KFO97075.1 - 0.004 16.5 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SepSecS PF05889.13 KFO97075.1 - 0.0055 15.4 0.0 0.009 14.7 0.0 1.3 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS OKR_DC_1 PF01276.20 KFO97075.1 - 0.034 12.9 0.0 0.054 12.2 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_1_2 PF00155.21 KFO97075.1 - 0.074 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II zf-C2H2 PF00096.26 KFO97076.1 - 4e-19 67.9 15.4 1e-07 32.0 0.8 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO97076.1 - 7.9e-18 64.0 20.4 5.2e-10 39.3 1.1 3.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFO97076.1 - 1.4e-13 50.4 15.3 8.6e-06 26.2 2.0 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO97076.1 - 2.5e-06 27.6 4.0 0.031 14.6 0.6 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFO97076.1 - 8.4e-06 26.0 6.2 0.0077 16.6 0.7 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFO97076.1 - 1.2e-05 25.1 12.2 0.011 15.8 0.7 3.7 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFO97076.1 - 4.5e-05 23.2 3.3 0.12 12.3 1.0 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-Di19 PF05605.12 KFO97076.1 - 4.8e-05 23.6 4.5 5.3e-05 23.4 2.2 2.1 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 KFO97076.1 - 0.00028 20.8 9.4 1.4 9.0 0.2 3.2 1 1 2 3 3 3 3 BED zinc finger zf-C2H2_8 PF15909.5 KFO97076.1 - 0.0011 19.3 3.2 0.0012 19.1 3.2 1.1 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 KFO97076.1 - 0.0019 17.9 12.1 0.018 14.8 0.1 3.4 3 0 0 3 3 3 1 C2H2-type zinc-finger domain FOXP-CC PF16159.5 KFO97076.1 - 0.0039 17.8 4.5 0.23 12.1 0.3 2.9 1 1 2 3 3 3 1 FOXP coiled-coil domain Zn-C2H2_12 PF18112.1 KFO97076.1 - 0.011 16.2 6.4 0.59 10.7 1.9 3.3 3 2 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_2 PF12756.7 KFO97076.1 - 0.011 16.0 4.0 0.9 9.9 0.6 2.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Prok-RING_4 PF14447.6 KFO97076.1 - 0.034 14.0 0.9 0.13 12.1 0.9 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C2H2_9 PF16293.5 KFO97076.1 - 0.043 13.7 0.3 0.043 13.7 0.3 2.2 3 0 0 3 3 2 0 C2H2 type zinc-finger (1 copy) zf_C2H2_ZHX PF18387.1 KFO97076.1 - 0.053 13.2 6.3 0.29 10.8 0.5 2.7 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-LYAR PF08790.11 KFO97076.1 - 0.083 12.8 2.9 7.8 6.5 0.0 3.0 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger DUF2225 PF09986.9 KFO97076.1 - 0.097 12.4 0.2 0.097 12.4 0.2 1.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-Sec23_Sec24 PF04810.15 KFO97076.1 - 0.11 12.6 2.2 0.46 10.6 0.1 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf_UBZ PF18439.1 KFO97076.1 - 0.2 11.3 1.6 5 6.8 0.1 2.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Myosin_head PF00063.21 KFO97077.1 - 1.8e-203 677.6 2.3 2.2e-203 677.3 2.3 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Pkinase PF00069.25 KFO97077.1 - 1.3e-57 195.2 0.0 2.3e-57 194.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO97077.1 - 6.6e-41 140.3 0.0 1.1e-40 139.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFO97077.1 - 8.2e-07 29.2 0.0 0.012 15.6 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFO97077.1 - 4e-06 25.9 0.0 7.2e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFO97077.1 - 0.00023 20.6 0.0 0.00047 19.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like IQ PF00612.27 KFO97077.1 - 0.0015 18.1 8.0 0.019 14.7 0.1 3.0 3 0 0 3 3 3 2 IQ calmodulin-binding motif AAA_22 PF13401.6 KFO97077.1 - 0.024 14.9 0.0 0.071 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFO97077.1 - 0.11 12.8 0.0 0.38 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 KFO97077.1 - 0.14 11.5 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin APH_6_hur PF04655.14 KFO97077.1 - 0.18 11.2 0.1 0.63 9.4 0.0 1.9 2 0 0 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase MTS PF05175.14 KFO97078.1 - 1.1e-14 54.3 0.1 1.6e-14 53.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KFO97078.1 - 3.9e-11 42.9 0.1 6.4e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KFO97078.1 - 1e-09 39.0 0.2 3.4e-09 37.3 0.1 1.9 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFO97078.1 - 1.4e-09 38.0 0.1 2.1e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KFO97078.1 - 9.3e-09 35.2 0.0 1.3e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 KFO97078.1 - 3.8e-07 30.0 0.5 3.8e-06 26.7 0.5 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.10 KFO97078.1 - 1.4e-05 24.7 0.1 2.1e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_12 PF08242.12 KFO97078.1 - 0.00021 22.0 0.0 0.00059 20.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain DNA_methylase PF00145.17 KFO97078.1 - 0.0055 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase FmrO PF07091.11 KFO97078.1 - 0.0066 16.0 0.1 0.017 14.7 0.1 1.6 1 1 1 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) N6_Mtase PF02384.16 KFO97078.1 - 0.01 15.2 0.2 0.018 14.3 0.2 1.6 1 1 0 1 1 1 0 N-6 DNA Methylase Methyltransf_4 PF02390.17 KFO97078.1 - 0.01 15.3 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.9 KFO97078.1 - 0.023 14.5 0.6 0.047 13.4 0.1 1.7 2 1 0 2 2 2 0 Lysine methyltransferase N6-adenineMlase PF10237.9 KFO97078.1 - 0.027 14.3 0.1 0.038 13.8 0.1 1.3 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase DUF43 PF01861.16 KFO97078.1 - 0.035 13.3 0.0 0.065 12.4 0.0 1.4 1 1 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Pfg27 PF09216.10 KFO97078.1 - 0.058 13.2 0.9 0.087 12.6 0.9 1.2 1 0 0 1 1 1 0 Pfg27 Methyltransf_9 PF08003.11 KFO97078.1 - 0.06 12.3 0.4 0.087 11.7 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltr_RsmB-F PF01189.17 KFO97078.1 - 0.083 12.5 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F RRM_3 PF08777.11 KFO97079.1 - 6.5e-27 93.6 2.1 6.5e-27 93.6 2.1 3.1 3 1 0 3 3 3 1 RNA binding motif La PF05383.17 KFO97079.1 - 9.2e-23 80.1 0.1 1.7e-22 79.2 0.1 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KFO97079.1 - 1.8e-14 53.3 0.3 2.2e-09 37.0 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kelch_1 PF01344.25 KFO97080.1 - 1.1e-46 156.1 32.0 6.2e-12 44.9 0.3 7.2 7 1 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 KFO97080.1 - 3.3e-34 116.0 11.9 1.9e-08 34.3 0.1 6.4 3 2 3 6 6 6 6 Kelch motif BTB PF00651.31 KFO97080.1 - 2.2e-30 105.1 1.3 3.4e-30 104.5 1.3 1.3 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KFO97080.1 - 6.4e-25 87.2 3.4 6.4e-25 87.2 3.4 2.4 3 0 0 3 3 3 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 KFO97080.1 - 1.5e-24 85.8 5.5 8.1e-05 22.6 0.0 6.6 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KFO97080.1 - 1.7e-21 75.3 16.5 0.00031 20.6 0.0 7.1 6 2 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KFO97080.1 - 2.7e-15 56.2 11.5 3.4e-06 27.2 0.1 5.6 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KFO97080.1 - 6.1e-06 26.1 22.5 0.39 10.8 0.1 6.3 7 0 0 7 7 7 4 Kelch motif DUF3342 PF11822.8 KFO97080.1 - 0.00066 19.8 0.1 0.002 18.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Skp1_POZ PF03931.15 KFO97080.1 - 0.076 13.2 0.0 0.32 11.2 0.0 2.1 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain Put_Phosphatase PF06888.12 KFO97081.1 - 1.8e-90 302.4 0.1 2.1e-90 302.2 0.1 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 KFO97081.1 - 2.4e-09 37.9 0.1 5.2e-08 33.5 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFO97081.1 - 0.037 14.3 0.0 3 8.1 0.0 2.3 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFO97081.1 - 0.068 13.3 1.3 10 6.2 1.4 3.0 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase TPH PF13868.6 KFO97082.1 - 2.2e-18 65.9 123.6 2.2e-18 65.9 123.6 2.1 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain Pro_isomerase PF00160.21 KFO97083.1 - 5.3e-48 163.3 0.2 5.3e-48 163.3 0.2 2.5 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SR-25 PF10500.9 KFO97083.1 - 2.2e-07 30.7 39.3 2.2e-07 30.7 39.3 5.6 2 1 3 5 5 5 1 Nuclear RNA-splicing-associated protein FAST_2 PF08368.12 KFO97084.1 - 3.7e-30 104.5 2.0 1.4e-28 99.5 0.0 3.6 4 0 0 4 4 4 1 FAST kinase-like protein, subdomain 2 FAST_1 PF06743.15 KFO97084.1 - 2.2e-18 66.0 21.6 1.6e-17 63.2 1.1 5.4 6 0 0 6 6 6 2 FAST kinase-like protein, subdomain 1 RAP PF08373.10 KFO97084.1 - 2.6e-14 53.1 1.3 8.2e-14 51.4 0.1 2.5 2 0 0 2 2 2 1 RAP domain Kelch_1 PF01344.25 KFO97085.1 - 2e-44 148.9 0.0 1.3e-09 37.5 0.0 5.5 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KFO97085.1 - 4.9e-31 106.0 0.0 8.7e-09 35.4 0.0 5.5 2 1 3 5 5 5 5 Kelch motif BACK PF07707.15 KFO97085.1 - 1.4e-30 105.4 0.3 4.2e-30 103.9 0.1 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 KFO97085.1 - 3.6e-28 98.0 0.4 7.7e-28 96.9 0.4 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 KFO97085.1 - 5.4e-21 74.3 0.0 3.1e-07 30.3 0.0 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KFO97085.1 - 2.1e-19 69.3 0.0 0.004 17.4 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KFO97085.1 - 3.4e-17 61.7 0.1 0.11 12.5 0.0 5.5 4 1 1 5 5 5 5 Kelch motif Kelch_5 PF13854.6 KFO97085.1 - 1.9e-13 50.0 0.0 0.1 12.6 0.0 5.4 5 0 0 5 5 5 4 Kelch motif DUF3342 PF11822.8 KFO97085.1 - 0.00069 19.8 0.2 0.018 15.2 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) BBL5 PF07289.11 KFO97086.1 - 1.7e-156 520.4 0.2 1.9e-156 520.2 0.2 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein bPH_3 PF14470.6 KFO97086.1 - 4.8e-05 23.6 0.1 0.0016 18.7 0.0 2.3 2 0 0 2 2 2 1 Bacterial PH domain GRAM PF02893.20 KFO97086.1 - 7e-05 22.7 0.1 0.04 13.8 0.0 2.6 2 1 1 3 3 3 2 GRAM domain Vps36_ESCRT-II PF11605.8 KFO97086.1 - 9.7e-05 22.5 0.1 0.17 12.1 0.0 2.4 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 PH_TFIIH PF08567.11 KFO97086.1 - 0.00083 19.6 0.0 0.15 12.4 0.0 2.5 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain Voldacs PF03517.13 KFO97086.1 - 0.0025 17.9 0.8 0.36 10.9 0.2 2.6 2 1 0 2 2 2 2 Regulator of volume decrease after cellular swelling Collagen PF01391.18 KFO97087.1 - 9e-70 230.3 298.7 4.8e-10 39.0 22.8 12.1 2 2 6 9 9 9 8 Collagen triple helix repeat (20 copies) VWA PF00092.28 KFO97087.1 - 2.6e-68 229.7 1.5 5.3e-40 137.5 0.5 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 KFO97087.1 - 2.8e-31 108.3 0.1 4.5e-20 72.3 0.1 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.6 KFO97087.1 - 1.2e-07 31.8 0.1 8e-05 22.6 0.0 3.0 3 0 0 3 3 3 2 von Willebrand factor type A domain Ldl_recept_a PF00057.18 KFO97088.1 - 0 1096.9 677.2 5.6e-12 45.7 9.2 38.4 38 1 0 38 38 38 36 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 KFO97088.1 - 8e-209 676.0 92.7 1.7e-11 44.4 0.0 37.9 38 1 0 38 38 38 29 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 KFO97088.1 - 2e-61 203.9 329.3 2.1e-10 40.7 5.1 24.3 22 1 0 22 22 22 15 Coagulation Factor Xa inhibitory site DUF5050 PF16472.5 KFO97088.1 - 1.2e-33 116.6 0.5 1.9e-07 30.6 0.0 10.4 8 2 0 9 9 9 9 Domain of unknown function (DUF5050) cEGF PF12662.7 KFO97088.1 - 1.8e-31 107.7 144.3 3.6e-10 39.6 1.7 19.1 18 0 0 18 18 18 10 Complement Clr-like EGF-like SGL PF08450.12 KFO97088.1 - 2.7e-13 50.1 38.6 0.026 14.1 1.0 15.2 9 7 2 14 14 14 4 SMP-30/Gluconolactonase/LRE-like region EGF_CA PF07645.15 KFO97088.1 - 5.3e-12 45.7 44.1 3.7e-08 33.4 6.9 35.6 28 8 10 40 40 40 6 Calcium-binding EGF domain Arylesterase PF01731.20 KFO97088.1 - 5.1e-05 23.4 0.0 31 4.8 0.1 8.6 11 1 0 11 11 11 0 Arylesterase adh_short PF00106.25 KFO97089.1 - 1.4e-22 80.2 0.0 1.8e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFO97089.1 - 8.6e-13 48.4 0.0 1.3e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KFO97089.1 - 7.7e-06 25.5 0.0 4.5e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KFO97089.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 KR domain PAP2 PF01569.21 KFO97090.1 - 2.3e-15 56.6 6.2 2.3e-15 56.6 6.2 1.8 2 0 0 2 2 2 1 PAP2 superfamily SpoVAB PF13782.6 KFO97090.1 - 0.13 12.5 2.4 0.46 10.8 2.4 1.8 1 0 0 1 1 1 0 Stage V sporulation protein AB Spindle_Spc25 PF08234.12 KFO97091.1 - 1.4e-24 86.1 0.3 4.4e-24 84.5 0.3 1.9 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Atg14 PF10186.9 KFO97091.1 - 0.018 14.1 12.5 0.024 13.7 12.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-H PF05837.12 KFO97091.1 - 0.044 14.2 11.1 0.1 13.0 11.1 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Spc7 PF08317.11 KFO97091.1 - 0.058 12.3 14.4 0.084 11.7 14.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DHR10 PF18595.1 KFO97091.1 - 0.11 12.6 16.0 0.18 11.8 15.1 1.8 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain CorA PF01544.18 KFO97091.1 - 0.36 10.1 8.5 0.61 9.3 8.6 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein ATP-synt_F6 PF05511.11 KFO97091.1 - 0.61 10.5 5.3 27 5.3 0.2 3.2 2 1 1 3 3 3 0 Mitochondrial ATP synthase coupling factor 6 UPF0242 PF06785.11 KFO97091.1 - 0.68 10.0 15.4 1.2 9.2 15.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMPIT PF07851.13 KFO97091.1 - 1.7 7.8 10.8 2.6 7.2 10.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein Dynamin_N PF00350.23 KFO97091.1 - 3.3 7.7 11.3 1.6e+02 2.3 11.3 2.3 1 1 0 1 1 1 0 Dynamin family TRAM_LAG1_CLN8 PF03798.16 KFO97092.1 - 4.5e-40 137.5 24.3 5.7e-40 137.2 24.3 1.1 1 0 0 1 1 1 1 TLC domain Homeodomain PF00046.29 KFO97092.1 - 4.9e-07 29.5 1.0 8.5e-07 28.7 1.0 1.4 1 0 0 1 1 1 1 Homeodomain Pkinase PF00069.25 KFO97093.1 - 1.1e-60 205.3 0.0 1.3e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO97093.1 - 1.8e-44 152.0 0.0 2.6e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 KFO97093.1 - 4e-22 78.2 0.1 8.9e-22 77.1 0.1 1.6 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Kinase-like PF14531.6 KFO97093.1 - 0.00045 19.6 0.0 0.00077 18.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFO97093.1 - 0.0008 18.3 0.0 0.0022 16.8 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFO97093.1 - 0.073 13.0 0.0 0.62 9.9 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 KFO97093.1 - 0.087 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFO97093.1 - 0.098 11.6 0.0 0.19 10.6 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Galactosyl_T PF01762.21 KFO97094.1 - 1e-60 204.9 0.0 1.3e-60 204.6 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Sel1 PF08238.12 KFO97095.1 - 1.3e-64 213.2 34.2 2.4e-09 37.5 0.2 12.7 13 0 0 13 13 13 11 Sel1 repeat fn2 PF00040.19 KFO97095.1 - 7.3e-18 64.6 6.4 1.3e-17 63.7 6.4 1.5 1 0 0 1 1 1 1 Fibronectin type II domain SF3A2 PF16835.5 KFO97095.1 - 0.054 13.9 0.2 2.2 8.7 0.0 2.5 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) Stonin2_N PF12016.8 KFO97096.1 - 7.5e-162 538.5 38.0 1.3e-161 537.7 38.0 1.4 1 0 0 1 1 1 1 Stonin 2 Adap_comp_sub PF00928.21 KFO97096.1 - 4.4e-60 203.3 0.1 8.6e-60 202.3 0.1 1.5 1 0 0 1 1 1 1 Adaptor complexes medium subunit family TFIIA PF03153.13 KFO97097.1 - 2e-91 308.0 81.8 5.5e-54 184.8 21.9 2.5 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit SelP_N PF04592.14 KFO97097.1 - 0.013 14.9 7.7 0.013 14.9 7.7 1.8 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF2052 PF09747.9 KFO97097.1 - 0.31 11.1 17.2 0.43 10.7 7.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) RPN2_C PF18004.1 KFO97097.1 - 1.4 8.8 12.4 0.18 11.7 3.1 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain 7tm_1 PF00001.21 KFO97098.1 - 2.5e-37 128.7 19.3 3.4e-37 128.2 19.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.6 KFO97098.1 - 2.7e-07 30.3 0.8 8e-05 22.3 0.1 2.9 1 1 2 3 3 3 3 Leucine rich repeat LRR_5 PF13306.6 KFO97098.1 - 0.0021 18.0 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) DUF5036 PF16439.5 KFO97099.1 - 0.021 14.6 0.0 0.06 13.1 0.0 1.7 1 1 0 2 2 2 0 Domain of unknown function (DUF5036) APG6_N PF17675.1 KFO97099.1 - 0.033 14.7 63.2 0.058 13.9 15.5 4.5 2 1 2 4 4 4 0 Apg6 coiled-coil region Senescence PF06911.12 KFO97099.1 - 0.063 13.6 0.2 0.3 11.4 0.1 1.9 2 0 0 2 2 2 0 Senescence-associated protein Fib_alpha PF08702.10 KFO97099.1 - 5.4 7.2 43.2 0.83 9.8 10.0 4.0 2 1 1 4 4 4 0 Fibrinogen alpha/beta chain family ALIX_LYPXL_bnd PF13949.6 KFO97099.1 - 7 5.8 46.9 1.5 8.0 0.8 3.5 2 1 1 3 3 3 0 ALIX V-shaped domain binding to HIV Filament PF00038.21 KFO97100.1 - 0.019 14.6 27.3 0.023 14.3 27.3 1.1 1 0 0 1 1 1 0 Intermediate filament protein APG6_N PF17675.1 KFO97100.1 - 0.059 13.9 37.2 2.5 8.6 17.3 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region GAS PF13851.6 KFO97100.1 - 0.069 12.5 34.9 0.28 10.5 19.8 2.5 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-H PF05837.12 KFO97100.1 - 0.14 12.6 26.2 0.071 13.5 9.5 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF5129 PF17173.4 KFO97100.1 - 0.3 10.2 4.9 0.45 9.6 0.7 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF5129) ADIP PF11559.8 KFO97100.1 - 0.42 10.7 28.7 0.32 11.1 7.3 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YlqD PF11068.8 KFO97100.1 - 0.89 9.9 28.7 0.29 11.5 12.9 2.3 1 1 1 2 2 2 0 YlqD protein TPR_MLP1_2 PF07926.12 KFO97100.1 - 0.99 9.5 27.9 2.9 7.9 17.5 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TIP49 PF06068.13 KFO97100.1 - 1.5 7.9 11.4 1.8 7.7 11.4 1.0 1 0 0 1 1 1 0 TIP49 P-loop domain DUF4407 PF14362.6 KFO97100.1 - 1.5 8.1 11.8 1.9 7.7 11.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5387 PF17361.2 KFO97100.1 - 1.7 8.3 10.1 2.6 7.7 10.1 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5387) Exonuc_VII_L PF02601.15 KFO97100.1 - 3.9 7.0 17.4 4.9 6.6 17.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit EPOP PF15223.6 KFO97100.1 - 5.7 6.2 14.2 21 4.3 14.2 1.8 1 1 0 1 1 1 0 Elongin BC and Polycomb repressive complex 2-associated protein YabA PF06156.13 KFO97100.1 - 6.5 7.5 24.5 0.22 12.2 8.0 2.8 1 1 2 3 3 3 0 Initiation control protein YabA Peptidase_C3 PF00548.20 KFO97100.1 - 8.6 6.2 8.4 3.4 7.6 3.6 2.0 1 1 1 2 2 2 0 3C cysteine protease (picornain 3C) CCDC-167 PF15188.6 KFO97101.1 - 0.23 11.8 11.0 1.1 9.6 4.1 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 T4_deiodinase PF00837.17 KFO97103.1 - 3.4e-11 42.9 0.2 3.5e-11 42.9 0.2 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase Syndecan PF01034.20 KFO97104.1 - 2.7e-08 33.6 0.0 6.5e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Syndecan domain CD34_antigen PF06365.12 KFO97104.1 - 0.014 14.9 0.1 0.021 14.4 0.1 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF202 PF02656.15 KFO97104.1 - 0.015 15.7 0.0 0.023 15.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF202) COX14 PF14880.6 KFO97104.1 - 0.14 12.0 0.2 0.29 11.0 0.2 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Orf78 PF06024.12 KFO97104.1 - 5.5 7.3 5.8 0.55 10.6 0.3 2.0 1 1 1 2 2 2 0 Orf78 (ac78) Laminin_G_2 PF02210.24 KFO97105.1 - 2.5e-16 60.4 0.1 3.6e-16 59.9 0.1 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFO97105.1 - 1.3e-05 25.4 0.2 2.1e-05 24.7 0.2 1.7 1 1 0 1 1 1 1 Laminin G domain Na_trans_cytopl PF11933.8 KFO97105.1 - 0.089 12.6 0.1 0.13 12.1 0.1 1.1 1 0 0 1 1 1 0 Cytoplasmic domain of voltage-gated Na+ ion channel DUF3439 PF11921.8 KFO97105.1 - 0.29 11.1 5.3 0.47 10.4 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Axin_b-cat_bind PF08833.10 KFO97106.1 - 0.046 13.8 1.1 0.046 13.8 1.1 1.5 2 0 0 2 2 2 0 Axin beta-catenin binding domain ABC1 PF03109.16 KFO97107.1 - 2.2e-39 134.3 0.1 3.7e-39 133.6 0.1 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 KFO97107.1 - 1.4e-06 27.8 0.0 0.00018 21.0 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KFO97107.1 - 0.00081 19.4 0.2 0.17 11.8 0.2 2.7 2 0 0 2 2 2 2 Phosphotransferase enzyme family RRM_1 PF00076.22 KFO97108.1 - 2.1e-10 40.3 0.0 2.4e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFO97108.1 - 0.1 12.6 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif 2OG-FeII_Oxy_2 PF13532.6 KFO97109.1 - 7.2e-38 130.7 0.0 1.4e-37 129.8 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMOP PF03782.17 KFO97110.1 - 2.2e-26 92.7 0.8 2.2e-26 92.7 0.8 1.9 2 0 0 2 2 2 1 AMOP domain TSP_1 PF00090.19 KFO97110.1 - 2.5e-07 30.8 11.8 2.5e-07 30.8 11.8 2.3 2 0 0 2 2 2 1 Thrombospondin type 1 domain Aha1_N PF09229.11 KFO97111.1 - 7.6e-43 146.0 0.6 1.2e-42 145.4 0.6 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KFO97111.1 - 7.3e-23 81.2 1.2 1.1e-22 80.6 0.4 1.7 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Vps16_C PF04840.12 KFO97112.1 - 1.8e-10 40.4 2.4 0.00024 20.3 0.1 2.2 2 0 0 2 2 2 2 Vps16, C-terminal region CREPT PF16566.5 KFO97112.1 - 2.4 8.3 5.7 1.4 9.1 1.2 2.5 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour GOLD_2 PF13897.6 KFO97114.1 - 1.4e-70 236.2 1.4 1.4e-70 236.2 1.4 1.6 2 0 0 2 2 2 1 Golgi-dynamics membrane-trafficking Kelch_4 PF13418.6 KFO97115.1 - 2.8e-24 84.9 0.0 9.2e-06 25.6 0.0 4.4 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KFO97115.1 - 2.1e-18 66.1 0.6 2.4e-06 27.7 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFO97115.1 - 8.2e-15 54.4 0.0 0.0024 17.8 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.25 KFO97115.1 - 3.1e-12 45.9 0.0 0.0083 15.7 0.0 3.5 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 KFO97115.1 - 1.9e-11 43.8 0.2 0.042 14.1 0.0 4.8 4 1 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 KFO97115.1 - 9.8e-11 41.2 0.1 0.00033 20.5 0.0 4.1 3 0 0 3 3 3 3 Kelch motif GST_N_3 PF13417.6 KFO97116.1 - 6.3e-16 58.6 0.0 1e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFO97116.1 - 9.6e-15 54.7 0.0 2.1e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFO97116.1 - 6.8e-13 48.7 0.0 1.3e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFO97116.1 - 3e-08 33.7 0.0 5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFO97116.1 - 7e-05 23.0 0.0 0.0001 22.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFO97116.1 - 0.0016 18.5 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KFO97116.1 - 0.041 14.5 0.0 0.06 13.9 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PMT PF02366.18 KFO97117.1 - 9.8e-81 270.9 14.5 9.8e-81 270.9 14.5 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KFO97117.1 - 4.4e-56 189.6 6.5 4.4e-56 189.6 6.5 1.9 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KFO97117.1 - 4.9e-23 82.0 0.1 7.3e-23 81.4 0.1 1.2 1 0 0 1 1 1 1 MIR domain Globin PF00042.22 KFO97118.1 - 4.3e-09 36.9 0.0 5.8e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Globin RSN1_7TM PF02714.15 KFO97119.1 - 1.3e-58 198.4 29.0 1.3e-58 198.4 29.0 1.9 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KFO97119.1 - 1.7e-49 168.5 0.5 2.4e-49 168.0 0.5 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KFO97119.1 - 7.6e-24 84.2 2.3 7.6e-24 84.2 2.3 5.2 6 1 0 6 6 6 1 Late exocytosis, associated with Golgi transport DHHC PF01529.20 KFO97120.1 - 6.9e-22 78.0 8.8 6.9e-22 78.0 8.8 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase InaF-motif PF15018.6 KFO97120.1 - 0.12 12.2 2.4 0.3 11.0 2.4 1.6 1 0 0 1 1 1 0 TRP-interacting helix CiPC PF15800.5 KFO97121.1 - 4.1e-105 352.2 10.2 5e-105 352.0 10.2 1.1 1 0 0 1 1 1 1 Clock interacting protein circadian Pyocin_S PF06958.12 KFO97121.1 - 0.16 12.5 0.8 0.43 11.1 0.4 1.9 1 1 0 1 1 1 0 S-type Pyocin IRF-2BP1_2 PF11261.8 KFO97122.1 - 3.8e-34 116.0 3.3 8.5e-34 114.9 3.3 1.6 1 0 0 1 1 1 1 Interferon regulatory factor 2-binding protein zinc finger zf-C3HC4 PF00097.25 KFO97122.1 - 0.0014 18.4 7.8 0.0046 16.8 7.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFO97122.1 - 0.065 13.1 7.3 0.19 11.6 7.3 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 KFO97122.1 - 1.1 9.5 7.9 3.5 7.8 0.1 2.7 2 0 0 2 2 2 0 Zinc-binding RING-finger TMEM219 PF14940.6 KFO97123.1 - 0.11 12.0 0.1 0.11 12.0 0.1 1.0 1 0 0 1 1 1 0 Transmembrane 219 Exo_endo_phos PF03372.23 KFO97124.1 - 2.4e-39 135.3 0.0 3.5e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family eIF_4G1 PF12152.8 KFO97124.1 - 0.14 12.4 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4G1 Vasohibin PF14822.6 KFO97125.1 - 4e-99 330.8 0.0 4.6e-99 330.6 0.0 1.0 1 0 0 1 1 1 1 Vasohibin RVT_1 PF00078.27 KFO97126.1 - 0.11 12.0 0.0 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Hormone_recep PF00104.30 KFO97127.1 - 4.1e-31 108.2 0.7 6.5e-31 107.5 0.7 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFO97127.1 - 7e-31 106.5 12.3 1.3e-30 105.7 12.3 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) CCD48 PF15799.5 KFO97127.1 - 0.16 10.3 1.6 0.23 9.8 1.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 IFT43 PF15305.6 KFO97129.1 - 4.7e-44 149.9 3.8 5.5e-44 149.6 3.8 1.1 1 0 0 1 1 1 1 Intraflagellar transport protein 43 TGF_beta PF00019.20 KFO97130.1 - 2.4e-24 86.3 1.0 4.1e-24 85.6 1.0 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFO97130.1 - 2.1e-20 73.5 0.0 2.9e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TTL PF03133.15 KFO97131.1 - 1.1e-90 303.8 0.0 3e-90 302.3 0.0 1.7 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KFO97131.1 - 1.1e-07 31.3 0.0 0.00085 18.6 0.0 2.7 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KFO97131.1 - 0.00048 19.5 0.0 0.17 11.1 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp XkdW PF09636.10 KFO97131.1 - 0.12 12.5 0.4 2.4 8.3 0.3 2.6 2 0 0 2 2 2 0 XkdW protein Erg28 PF03694.13 KFO97132.1 - 3.9e-09 36.9 4.7 5.1e-09 36.5 4.7 1.2 1 0 0 1 1 1 1 Erg28 like protein DUF1427 PF07235.11 KFO97132.1 - 0.054 13.4 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1427) MFS_1 PF07690.16 KFO97133.1 - 7.4e-28 97.5 49.5 7.4e-25 87.6 33.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0239 PF06783.11 KFO97133.1 - 0.62 10.3 1.9 0.55 10.5 0.2 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) bZIP_1 PF00170.21 KFO97134.1 - 3e-11 43.3 8.4 4.1e-11 42.8 8.4 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFO97134.1 - 8.6e-10 38.6 12.4 1.1e-09 38.3 12.4 1.1 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFO97134.1 - 4.7e-07 30.2 9.8 6.2e-07 29.9 9.8 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor Phlebovirus_NSM PF07246.11 KFO97134.1 - 0.00034 20.1 0.2 0.00039 19.9 0.2 1.2 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M TMCO5 PF14992.6 KFO97134.1 - 0.021 14.4 3.8 0.024 14.2 3.8 1.1 1 0 0 1 1 1 0 TMCO5 family SR-25 PF10500.9 KFO97134.1 - 0.026 14.1 7.2 0.029 14.0 7.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein APG6_N PF17675.1 KFO97134.1 - 0.03 14.9 4.7 0.037 14.6 4.7 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region HALZ PF02183.18 KFO97134.1 - 0.036 14.3 2.6 0.036 14.3 2.6 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF3450 PF11932.8 KFO97134.1 - 0.07 12.4 3.5 0.086 12.1 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) AAA_11 PF13086.6 KFO97134.1 - 0.32 10.8 4.9 0.38 10.5 4.9 1.1 1 0 0 1 1 1 0 AAA domain DivIC PF04977.15 KFO97134.1 - 3 7.7 7.3 9.8 6.0 7.3 1.8 1 1 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.21 KFO97135.1 - 7.6e-11 42.0 21.2 1.3e-10 41.2 21.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KFO97135.1 - 4.2e-08 33.6 12.0 6.6e-08 33.0 12.0 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 KFO97135.1 - 5.1e-08 32.9 22.4 8.7e-08 32.1 22.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper CBP_BcsG PF11658.8 KFO97135.1 - 0.022 13.2 0.1 0.026 12.9 0.1 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Macoilin PF09726.9 KFO97135.1 - 0.091 11.3 9.5 0.11 11.0 9.5 1.0 1 0 0 1 1 1 0 Macoilin family VGCC_beta4Aa_N PF12052.8 KFO97135.1 - 9.5 6.4 11.9 1 9.5 5.2 2.5 1 1 1 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal EMP24_GP25L PF01105.24 KFO97136.1 - 1.1e-36 126.5 0.1 1.2e-36 126.4 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pkinase PF00069.25 KFO97137.1 - 5.3e-51 173.5 0.1 8.1e-51 172.9 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain RCC1 PF00415.18 KFO97137.1 - 4.9e-49 164.7 22.5 2.2e-13 50.6 0.1 8.0 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFO97137.1 - 4.9e-35 118.6 21.8 2e-08 33.8 0.3 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.17 KFO97137.1 - 9.4e-34 116.9 0.1 9.4e-34 116.9 0.1 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFO97137.1 - 1.8e-05 23.7 0.0 2.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFO97137.1 - 0.0012 18.2 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFO97137.1 - 0.15 11.4 0.1 0.28 10.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C2HC_2 PF13913.6 KFO97138.1 - 2.9e-16 58.9 9.2 2.9e-08 33.4 1.5 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-CpG_bind_C PF12269.8 KFO97138.1 - 0.00016 21.5 0.3 0.44 10.3 0.0 2.1 1 1 1 2 2 2 2 CpG binding protein zinc finger C terminal domain zf-CHCC PF10276.9 KFO97138.1 - 0.0025 17.8 2.8 0.17 11.9 0.4 2.3 2 0 0 2 2 2 1 Zinc-finger domain FYVE PF01363.21 KFO97138.1 - 0.0069 16.5 2.1 0.24 11.6 0.2 2.2 2 0 0 2 2 2 1 FYVE zinc finger Clathrin_lg_ch PF01086.17 KFO97138.1 - 0.023 14.8 0.7 0.029 14.4 0.7 1.1 1 0 0 1 1 1 0 Clathrin light chain zf-C2H2_4 PF13894.6 KFO97138.1 - 0.047 14.5 9.8 1.6 9.8 3.4 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFO97138.1 - 0.064 13.7 5.1 4.2 8.0 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2HC5 PF06221.13 KFO97138.1 - 0.072 13.1 1.5 0.85 9.7 0.6 2.4 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Nairovirus_M PF07948.11 KFO97138.1 - 0.1 10.8 0.3 0.16 10.2 0.3 1.2 1 0 0 1 1 1 0 Nairovirus M polyprotein-like zinc_ribbon_9 PF14369.6 KFO97138.1 - 0.13 12.5 2.6 0.64 10.3 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon zf-Di19 PF05605.12 KFO97138.1 - 0.58 10.5 5.3 5.6 7.3 0.6 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.16 KFO97138.1 - 0.86 9.8 4.8 13 6.1 0.3 2.8 3 0 0 3 3 3 0 AN1-like Zinc finger zf-C4_ClpX PF06689.13 KFO97138.1 - 0.93 9.4 6.4 11 6.0 3.0 2.7 2 0 0 2 2 2 0 ClpX C4-type zinc finger zf-C2H2 PF00096.26 KFO97138.1 - 1.4 9.5 9.1 12 6.6 0.1 2.9 2 1 0 2 2 2 0 Zinc finger, C2H2 type DUF3039 PF11238.8 KFO97138.1 - 2.4 8.0 7.5 3.3 7.5 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3039) Sgf11 PF08209.11 KFO97138.1 - 6.8 6.3 10.5 3.5 7.3 2.6 3.0 2 1 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Acylphosphatase PF00708.18 KFO97139.1 - 5e-25 87.7 0.8 5.8e-25 87.5 0.8 1.1 1 0 0 1 1 1 1 Acylphosphatase MutL_C PF08676.11 KFO97140.1 - 8.3e-13 48.3 0.5 9e-12 45.0 0.3 2.7 2 1 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KFO97140.1 - 1.6e-11 43.9 0.0 1.7e-05 24.4 0.0 2.9 3 0 0 3 3 3 2 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 KFO97140.1 - 1.8e-08 34.9 0.1 7.6e-08 32.8 0.1 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFO97140.1 - 1.9e-08 34.2 0.1 5.9e-08 32.6 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IF-2B PF01008.17 KFO97141.1 - 2.7e-81 272.9 0.1 3.1e-81 272.7 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family MSC PF09402.10 KFO97141.1 - 0.14 11.6 0.0 0.29 10.5 0.0 1.4 1 1 1 2 2 2 0 Man1-Src1p-C-terminal domain PDGF PF00341.17 KFO97142.1 - 2.2e-26 92.0 5.7 2.5e-26 91.8 5.7 1.0 1 0 0 1 1 1 1 PDGF/VEGF domain Pkinase PF00069.25 KFO97143.1 - 1.4e-25 90.1 0.0 7.4e-24 84.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFO97143.1 - 4.9e-12 45.7 0.0 5.6e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MIT PF04212.18 KFO97143.1 - 0.0083 16.2 1.4 0.015 15.3 1.4 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Kinase-like PF14531.6 KFO97143.1 - 0.041 13.2 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like 2-oxoacid_dh PF00198.23 KFO97144.1 - 8.2e-81 270.9 0.2 1e-80 270.6 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFO97144.1 - 2.3e-22 78.6 0.5 4.1e-22 77.8 0.5 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KFO97144.1 - 0.0049 16.7 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like HlyD_D23 PF16576.5 KFO97144.1 - 0.099 11.8 0.0 0.56 9.4 0.0 2.0 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion GCV_H PF01597.19 KFO97144.1 - 0.14 12.1 0.8 0.31 10.9 0.8 1.6 1 1 0 1 1 1 0 Glycine cleavage H-protein Fcf1 PF04900.12 KFO97145.1 - 2.4e-39 133.7 2.3 3.2e-39 133.3 2.3 1.2 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KFO97145.1 - 4e-11 43.2 0.0 5e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 PIN like domain Imm-NTF2 PF15655.6 KFO97145.1 - 0.05 13.9 0.0 0.082 13.2 0.0 1.3 1 0 0 1 1 1 0 NTF2 fold immunity protein HECT PF00632.25 KFO97146.1 - 2.3e-78 263.8 0.2 3.7e-78 263.1 0.2 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Filamin PF00630.19 KFO97146.1 - 5.9e-10 39.9 0.7 3.4e-06 27.8 0.0 3.3 4 0 0 4 4 4 2 Filamin/ABP280 repeat EGF_CA PF07645.15 KFO97147.1 - 3.8e-106 347.1 267.0 3.1e-09 36.9 5.7 20.1 20 0 0 20 20 20 16 Calcium-binding EGF domain cEGF PF12662.7 KFO97147.1 - 1e-74 245.9 169.4 1.2e-09 37.9 3.3 20.3 20 0 0 20 20 20 17 Complement Clr-like EGF-like TB PF00683.17 KFO97147.1 - 1.7e-49 165.3 62.9 1.6e-16 59.7 6.9 6.4 5 0 0 5 5 5 4 TB domain EGF PF00008.27 KFO97147.1 - 2.6e-36 123.5 265.4 0.0001 22.5 5.4 22.3 21 1 0 22 22 22 16 EGF-like domain FXa_inhibition PF14670.6 KFO97147.1 - 2e-16 59.9 274.2 0.00017 21.8 5.0 21.4 17 3 4 21 21 21 13 Coagulation Factor Xa inhibitory site hEGF PF12661.7 KFO97147.1 - 1.8e-15 56.9 252.0 0.00025 21.6 5.3 23.5 24 0 0 24 24 24 14 Human growth factor-like EGF EGF_3 PF12947.7 KFO97147.1 - 4.3e-13 49.2 208.7 0.0027 17.8 1.7 20.3 19 0 0 19 19 19 13 EGF domain Plasmod_Pvs28 PF06247.11 KFO97147.1 - 1.1e-06 28.8 179.3 0.0081 16.5 5.0 17.9 16 1 1 17 17 17 11 Pvs28 EGF domain E1_DerP2_DerF2 PF02221.15 KFO97148.1 - 3.4e-31 108.5 0.4 3.7e-31 108.3 0.4 1.0 1 0 0 1 1 1 1 ML domain Fe-S_biosyn PF01521.20 KFO97149.1 - 3.3e-12 46.6 0.0 4.3e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis CD225 PF04505.12 KFO97150.1 - 8.2e-18 64.3 0.2 1.4e-17 63.6 0.2 1.4 1 0 0 1 1 1 1 Interferon-induced transmembrane protein HTH_Tnp_1 PF01527.20 KFO97151.1 - 4.4e-07 30.1 9.6 0.019 15.3 0.1 4.7 5 0 0 5 5 5 3 Transposase HTH_Tnp_1_2 PF13022.6 KFO97151.1 - 1.8e-06 28.1 1.7 2 8.6 0.1 4.4 4 0 0 4 4 4 2 Helix-turn-helix of insertion element transposase HTH_23 PF13384.6 KFO97151.1 - 7e-05 22.5 6.0 0.55 10.1 0.0 4.3 5 0 0 5 5 5 2 Homeodomain-like domain DUF1492 PF07374.11 KFO97151.1 - 0.00015 21.9 2.8 1.7 8.9 0.0 4.2 4 0 0 4 4 4 1 Protein of unknown function (DUF1492) HTH_28 PF13518.6 KFO97151.1 - 0.0054 16.8 2.9 7.8 6.7 0.0 4.4 4 0 0 4 4 4 1 Helix-turn-helix domain Cnl2_NKP2 PF09447.10 KFO97151.1 - 0.034 14.3 1.7 5.4 7.2 0.0 3.6 3 0 0 3 3 3 0 Cnl2/NKP2 family protein OTU PF02338.19 KFO97151.1 - 0.037 14.5 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 OTU-like cysteine protease HTH_29 PF13551.6 KFO97151.1 - 0.11 12.5 0.5 5.2 7.2 0.0 3.0 3 0 0 3 3 3 0 Winged helix-turn helix Cbl_N2 PF02761.14 KFO97151.1 - 0.12 13.1 1.2 13 6.6 0.1 3.4 4 0 0 4 4 4 0 CBL proto-oncogene N-terminus, EF hand-like domain ABC_membrane_2 PF06472.15 KFO97152.1 - 7.4e-79 264.9 2.6 1e-78 264.5 2.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KFO97152.1 - 4.1e-17 63.0 0.0 7.1e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_30 PF13604.6 KFO97152.1 - 0.00082 19.1 0.2 0.0042 16.8 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFO97152.1 - 0.0015 19.0 0.0 0.0033 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain SbmA_BacA PF05992.12 KFO97152.1 - 0.004 16.7 2.8 0.007 15.8 2.8 1.4 1 1 0 1 1 1 1 SbmA/BacA-like family AAA_21 PF13304.6 KFO97152.1 - 0.006 16.4 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KFO97152.1 - 0.013 15.0 0.1 0.024 14.1 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DEAD PF00270.29 KFO97152.1 - 0.021 14.6 0.1 0.19 11.5 0.1 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_23 PF13476.6 KFO97152.1 - 0.052 14.1 0.3 0.092 13.2 0.3 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFO97152.1 - 0.083 13.2 0.5 0.26 11.5 0.3 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KFO97152.1 - 0.096 12.4 0.2 0.2 11.5 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DLIC PF05783.11 KFO97152.1 - 0.13 11.0 0.1 0.22 10.3 0.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) NACHT PF05729.12 KFO97152.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 KFO97152.1 - 0.18 11.7 0.6 0.33 10.9 0.6 1.3 1 0 0 1 1 1 0 RsgA GTPase AMP-binding_C PF13193.6 KFO97153.1 - 4.8e-22 78.7 0.5 7.1e-22 78.2 0.5 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KFO97153.1 - 3e-10 39.3 0.0 3.7e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 KFO97154.1 - 7e-20 71.0 0.0 7.5e-20 70.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DUF1967 PF09269.11 KFO97154.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Homeodomain PF00046.29 KFO97155.1 - 2.6e-23 81.6 1.5 3.4e-23 81.2 1.5 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO97155.1 - 0.002 18.0 0.1 0.0033 17.3 0.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain LIN52 PF10044.9 KFO97156.1 - 1.6e-17 64.0 0.0 1.7e-17 63.9 0.0 1.0 1 0 0 1 1 1 1 Retinal tissue protein Aldedh PF00171.22 KFO97157.1 - 1.8e-122 409.2 0.0 2e-122 409.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KFO97157.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF4515 PF14988.6 KFO97158.1 - 3.8e-08 33.4 20.0 3.8e-08 33.4 20.0 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF4515) GDA1_CD39 PF01150.17 KFO97159.1 - 9.1e-77 258.5 0.0 3.5e-76 256.6 0.0 1.8 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family FAD_binding_3 PF01494.19 KFO97160.1 - 2.6e-17 63.1 0.2 1.9e-10 40.5 0.2 2.1 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 KFO97160.1 - 0.00047 19.3 0.0 0.00087 18.4 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.14 KFO97160.1 - 0.015 14.2 0.0 1 8.2 0.0 2.2 2 1 0 2 2 2 0 Tryptophan halogenase UPF0564 PF10595.9 KFO97161.1 - 2.7e-78 263.6 40.6 3.8e-78 263.1 40.6 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0564 DUF5412 PF17428.2 KFO97161.1 - 0.074 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5412) zf-H2C2_2 PF13465.6 KFO97162.1 - 6.5e-24 83.2 29.7 1.8e-06 28.1 0.3 6.2 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFO97162.1 - 3.6e-23 80.7 26.7 2.8e-05 24.3 0.1 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO97162.1 - 2.5e-14 52.7 28.1 0.0012 19.5 4.0 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFO97162.1 - 3.5e-05 23.4 13.4 0.4 10.5 0.1 3.7 3 0 0 3 3 3 3 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 KFO97162.1 - 7.3e-05 23.0 7.4 0.011 16.0 1.5 3.5 2 1 3 5 5 5 2 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 KFO97162.1 - 7.6e-05 22.5 8.5 0.21 11.5 0.0 4.8 5 0 0 5 5 5 2 zinc-finger of a C2HC-type zf-C2H2_aberr PF17017.5 KFO97162.1 - 0.00013 22.2 7.9 2.1 8.5 0.1 4.3 1 1 3 4 4 4 2 Aberrant zinc-finger zf-met PF12874.7 KFO97162.1 - 0.0018 18.6 7.5 0.94 10.0 0.1 4.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFO97162.1 - 0.015 15.6 8.5 2.4 8.5 0.0 4.5 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding CpXC PF14353.6 KFO97162.1 - 0.067 13.2 0.8 5.4 7.1 0.0 2.9 2 1 1 3 3 3 0 CpXC protein CHORD PF04968.12 KFO97162.1 - 0.24 12.1 13.4 4.4 8.1 0.1 4.8 2 1 3 5 5 5 0 CHORD zf-C2H2_6 PF13912.6 KFO97162.1 - 0.44 10.6 30.4 6.2 6.9 0.2 6.0 5 1 0 5 5 5 0 C2H2-type zinc finger zf-DNA_Pol PF08996.10 KFO97162.1 - 0.51 10.1 3.5 6.7 6.4 0.1 2.4 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf-C2H2_2 PF12756.7 KFO97162.1 - 0.74 10.2 9.6 0.47 10.8 0.9 3.6 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 KFO97162.1 - 5.7 6.8 23.7 0.23 11.2 0.3 5.2 5 0 0 5 5 5 0 C2H2-type zinc-finger domain Pinin_SDK_N PF04697.13 KFO97164.1 - 8.4e-51 172.2 6.2 8.4e-51 172.2 6.2 5.3 4 2 1 5 5 5 1 pinin/SDK conserved region Pinin_SDK_memA PF04696.13 KFO97164.1 - 1.2e-33 115.9 18.5 1.2e-33 115.9 18.5 6.4 4 2 2 6 6 6 1 pinin/SDK/memA/ protein conserved region TRAPP PF04051.16 KFO97165.1 - 3.2e-33 114.5 0.1 3.6e-33 114.4 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component SIP1 PF04938.12 KFO97166.1 - 1.5e-79 266.7 0.3 1.8e-79 266.5 0.3 1.0 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Sec23_trunk PF04811.15 KFO97167.1 - 9e-80 267.7 0.0 1.3e-79 267.2 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KFO97167.1 - 3.7e-33 114.1 0.0 8.1e-33 113.0 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KFO97167.1 - 1.5e-27 95.4 0.0 3.5e-27 94.2 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KFO97167.1 - 2.7e-15 56.1 6.7 5.1e-15 55.2 6.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KFO97167.1 - 7.7e-15 54.6 0.0 2.4e-14 53.0 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat APP_E2 PF12925.7 KFO97167.1 - 0.014 15.1 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein 7tm_1 PF00001.21 KFO97168.1 - 1.3e-63 214.8 27.2 1.7e-63 214.5 27.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFO97168.1 - 3.7e-14 52.7 24.1 4.7e-14 52.4 24.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFO97168.1 - 5.4e-10 39.3 22.8 1.9e-09 37.6 22.8 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFO97168.1 - 8.9e-09 35.1 14.9 8.9e-09 35.1 14.9 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFO97168.1 - 0.00026 20.9 22.8 0.00052 19.8 22.8 1.5 1 1 0 1 1 1 1 Olfactory receptor Piezo_RRas_bdg PF12166.8 KFO97168.1 - 0.0031 16.9 1.2 0.14 11.4 0.1 2.3 2 0 0 2 2 2 1 Piezo non-specific cation channel, R-Ras-binding domain T2SSM PF04612.12 KFO97168.1 - 0.078 13.0 0.2 0.078 13.0 0.2 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M COX7C PF02935.16 KFO97168.1 - 0.37 11.1 8.1 0.53 10.6 0.3 2.8 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIIc DUF3995 PF13160.6 KFO97168.1 - 8 6.8 11.8 9 6.7 3.3 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF3995) TPR_1 PF00515.28 KFO97169.1 - 2.1e-58 191.9 56.9 2.6e-06 27.0 0.3 17.5 17 2 1 18 18 18 13 Tetratricopeptide repeat TPR_2 PF07719.17 KFO97169.1 - 1e-51 168.9 41.5 3.2e-05 23.7 0.0 17.9 17 3 1 18 18 18 13 Tetratricopeptide repeat TPR_11 PF13414.6 KFO97169.1 - 7.5e-42 140.8 30.8 1.4e-05 24.7 0.0 13.7 8 3 5 13 13 13 9 TPR repeat TPR_9 PF13371.6 KFO97169.1 - 9.8e-34 115.3 0.1 0.00014 21.9 0.0 8.5 4 3 4 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 KFO97169.1 - 9.8e-34 112.7 45.6 0.00019 21.4 0.1 16.1 16 1 1 17 17 17 9 Tetratricopeptide repeat TPR_17 PF13431.6 KFO97169.1 - 4.5e-27 92.4 29.9 0.0025 18.1 0.1 12.1 13 0 0 13 13 12 6 Tetratricopeptide repeat TPR_16 PF13432.6 KFO97169.1 - 5.5e-23 81.3 2.2 0.017 15.7 0.0 10.3 9 2 2 11 11 11 5 Tetratricopeptide repeat TPR_12 PF13424.6 KFO97169.1 - 1.7e-22 79.5 19.1 1.1e-05 25.6 0.0 11.2 7 3 4 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFO97169.1 - 3.4e-17 61.7 5.5 0.36 11.8 0.0 12.2 7 5 7 14 14 14 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFO97169.1 - 4.8e-15 55.8 18.3 2.5e-06 27.9 0.0 8.8 4 2 6 10 10 10 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO97169.1 - 2.6e-11 43.6 31.6 0.00015 21.9 2.6 6.7 5 2 2 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KFO97169.1 - 2.3e-10 39.8 13.3 1.1 9.4 0.0 10.5 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_15 PF13429.6 KFO97169.1 - 2.5e-08 33.5 2.1 3.1 6.9 0.0 6.4 3 2 2 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFO97169.1 - 1.5e-07 31.5 29.6 1 10.2 0.2 11.6 15 1 0 15 15 11 4 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFO97169.1 - 4.7e-05 23.4 11.8 0.079 13.0 0.0 6.0 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.9 KFO97169.1 - 0.0045 16.4 13.1 0.22 11.0 0.0 8.3 11 0 0 11 11 11 1 SHNi-TPR TPR_10 PF13374.6 KFO97169.1 - 0.06 13.2 16.5 8.7 6.4 0.0 7.7 9 0 0 9 9 9 0 Tetratricopeptide repeat DUF627 PF04781.12 KFO97169.1 - 0.11 12.6 10.0 18 5.4 0.7 5.6 4 1 1 5 5 5 0 Protein of unknown function (DUF627) Forkhead PF00250.18 KFO97170.1 - 4.8e-38 129.3 0.2 8.5e-38 128.5 0.2 1.4 1 0 0 1 1 1 1 Forkhead domain HNF_C PF09354.10 KFO97170.1 - 2.1e-28 99.1 3.9 2.1e-28 99.1 3.9 4.0 3 1 0 3 3 3 1 HNF3 C-terminal domain Forkhead_N PF08430.12 KFO97170.1 - 2.9e-25 89.5 30.7 2.9e-25 89.5 30.7 3.1 2 1 1 3 3 3 1 Forkhead N-terminal region CYYR1 PF10873.8 KFO97170.1 - 1.2 9.6 6.0 1.6 9.1 0.2 2.6 3 0 0 3 3 3 0 Cysteine and tyrosine-rich protein 1 NPBW PF15180.6 KFO97171.1 - 0.82 9.5 3.2 3.4 7.5 0.6 2.7 1 1 1 2 2 2 0 Neuropeptides B and W RNA_polI_A14 PF08203.11 KFO97171.1 - 2.7 8.8 7.0 0.89 10.3 0.7 2.8 1 1 1 2 2 2 0 Yeast RNA polymerase I subunit RPA14 Mito_carr PF00153.27 KFO97172.1 - 8.7e-50 166.6 1.7 2.1e-19 69.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PAX PF00292.18 KFO97173.1 - 2.9e-66 221.1 0.2 4.5e-66 220.5 0.2 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 KFO97173.1 - 7.4e-07 28.8 0.2 2e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 KFO97173.1 - 1.3e-05 25.7 0.3 0.00028 21.4 0.0 2.3 1 1 1 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFO97173.1 - 0.0087 16.1 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 KFO97173.1 - 0.042 14.0 0.0 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Homeodomain PF00046.29 KFO97174.1 - 1.9e-20 72.4 4.8 3.4e-20 71.6 4.8 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO97174.1 - 0.078 12.9 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain Sds3 PF08598.11 KFO97176.1 - 7.1e-25 88.3 8.7 2.5e-24 86.5 8.9 1.5 1 1 1 2 2 2 1 Sds3-like Borrelia_P83 PF05262.11 KFO97176.1 - 0.21 10.0 5.7 0.29 9.6 5.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Ank PF00023.30 KFO97177.1 - 1.1e-26 92.0 6.7 1.6e-06 28.3 0.1 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.7 KFO97177.1 - 1.1e-26 93.2 3.8 1.3e-13 51.3 0.3 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFO97177.1 - 1.9e-24 85.4 1.1 1.3e-09 38.1 0.0 3.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFO97177.1 - 4e-23 79.0 2.9 1.9e-05 24.6 0.0 4.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KFO97177.1 - 7.2e-21 74.3 1.0 6.3e-09 36.2 0.1 4.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) CRR7 PF12095.8 KFO97177.1 - 0.032 14.7 0.2 0.18 12.3 0.0 2.2 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 Proteasome PF00227.26 KFO97178.1 - 2.5e-53 180.4 0.2 2.9e-53 180.2 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit PRORP PF16953.5 KFO97179.1 - 1.8e-93 312.5 1.1 3e-93 311.8 1.1 1.4 1 0 0 1 1 1 1 Protein-only RNase P PPR_2 PF13041.6 KFO97179.1 - 4.5e-08 33.2 0.9 0.041 14.1 0.0 3.8 2 1 1 3 3 3 3 PPR repeat family RNase_Zc3h12a PF11977.8 KFO97179.1 - 5.5e-05 23.0 0.1 0.00018 21.3 0.1 1.9 1 1 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PPR PF01535.20 KFO97179.1 - 0.00038 20.5 12.9 0.014 15.6 0.1 4.6 5 0 0 5 5 5 2 PPR repeat PPR_long PF17177.4 KFO97179.1 - 0.004 16.5 0.0 0.0075 15.6 0.0 1.5 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP Rad50_zn_hook PF04423.14 KFO97179.1 - 0.0098 15.7 0.7 0.32 10.9 0.4 2.9 2 1 0 2 2 2 1 Rad50 zinc hook motif Y_Y_Y PF07495.13 KFO97179.1 - 0.14 12.1 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Y_Y_Y domain EF-hand_7 PF13499.6 KFO97180.1 - 9.6e-09 35.6 7.6 2.7e-05 24.5 0.2 5.0 4 1 1 5 5 5 2 EF-hand domain pair EF-hand_6 PF13405.6 KFO97180.1 - 2.4e-06 27.0 3.9 0.49 10.5 0.1 5.3 5 0 0 5 5 5 2 EF-hand domain EF-hand_13 PF17958.1 KFO97180.1 - 7.6e-06 25.6 0.1 4.8e-05 23.1 0.0 2.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 KFO97180.1 - 4.2e-05 22.8 0.6 0.26 10.9 0.0 3.9 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KFO97180.1 - 0.011 15.6 0.0 1.8 8.5 0.0 3.0 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 KFO97180.1 - 0.029 13.9 0.9 0.13 11.8 0.0 2.6 3 0 0 3 3 3 0 EF hand FAM177 PF14774.6 KFO97181.1 - 4.4e-28 98.0 0.1 4.4e-28 98.0 0.1 2.0 1 1 1 2 2 2 1 FAM177 family DUF719 PF05334.13 KFO97181.1 - 0.00032 21.0 0.1 0.00038 20.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF719) PAF PF15715.5 KFO97181.1 - 0.0016 19.0 2.6 0.0019 18.8 2.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain Connexin PF00029.19 KFO97181.1 - 0.0034 17.2 0.3 0.0037 17.0 0.3 1.2 1 0 0 1 1 1 1 Connexin ZapB PF06005.12 KFO97181.1 - 0.015 15.7 7.2 0.022 15.2 7.2 1.2 1 0 0 1 1 1 0 Cell division protein ZapB CPSF100_C PF13299.6 KFO97181.1 - 0.05 13.8 0.8 0.058 13.6 0.8 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 KFO97181.1 - 2.9 6.6 3.8 3.1 6.5 3.8 1.1 1 0 0 1 1 1 0 Presenilin SRP54 PF00448.22 KFO97182.1 - 2.5e-77 258.9 0.3 1.2e-76 256.8 0.1 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KFO97182.1 - 2.4e-30 105.1 2.7 2.4e-30 105.1 2.7 3.2 2 1 2 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 KFO97182.1 - 1e-20 73.7 3.1 3.4e-20 72.1 3.1 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KFO97182.1 - 8.7e-07 28.7 0.7 8.5e-06 25.5 0.5 2.4 2 1 0 2 2 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KFO97182.1 - 5.5e-06 26.6 0.0 1.1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 KFO97182.1 - 3.4e-05 23.4 0.6 0.081 12.3 0.0 2.7 1 1 0 2 2 2 2 Signal recognition particle receptor beta subunit CbiA PF01656.23 KFO97182.1 - 5.4e-05 23.3 0.0 0.00021 21.3 0.0 2.0 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2209 PF09974.9 KFO97182.1 - 0.0003 21.1 0.3 0.0008 19.7 0.3 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2209) AAA_22 PF13401.6 KFO97182.1 - 0.00069 19.9 0.5 0.0066 16.7 0.1 2.7 3 1 0 3 3 2 1 AAA domain MeaB PF03308.16 KFO97182.1 - 0.0018 17.3 0.0 0.041 12.9 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KFO97182.1 - 0.0042 16.8 0.0 0.014 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_31 PF13614.6 KFO97182.1 - 0.0064 16.4 0.7 0.028 14.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFO97182.1 - 0.0091 16.1 2.0 0.023 14.8 0.2 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase ResIII PF04851.15 KFO97182.1 - 0.0095 15.9 0.4 0.029 14.4 0.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_17 PF13207.6 KFO97182.1 - 0.01 16.2 1.1 0.01 16.2 1.1 3.0 3 1 0 3 3 2 0 AAA domain CLP1_P PF16575.5 KFO97182.1 - 0.014 15.2 0.6 0.53 10.0 0.1 2.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 KFO97182.1 - 0.016 15.6 0.0 0.041 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 KFO97182.1 - 0.024 14.4 1.3 0.18 11.5 0.1 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.14 KFO97182.1 - 0.027 14.4 0.4 0.1 12.5 0.0 2.2 2 1 1 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 KFO97182.1 - 0.03 14.9 0.1 0.095 13.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KFO97182.1 - 0.03 14.2 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase GTP_EFTU PF00009.27 KFO97182.1 - 0.039 13.5 0.4 0.33 10.5 0.4 2.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain 6PF2K PF01591.18 KFO97182.1 - 0.041 13.2 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_28 PF13521.6 KFO97182.1 - 0.044 14.0 0.0 0.086 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KFO97182.1 - 0.05 12.7 0.5 0.36 10.0 0.3 2.5 1 1 0 1 1 1 0 G-protein alpha subunit AAA PF00004.29 KFO97182.1 - 0.06 13.8 2.0 0.51 10.8 0.2 3.2 2 2 1 3 3 1 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KFO97182.1 - 0.063 13.0 0.3 0.48 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain YlbD_coat PF14071.6 KFO97182.1 - 6.8 7.0 11.6 14 6.0 3.2 4.5 2 1 2 4 4 4 0 Putative coat protein Methyltransf_11 PF08241.12 KFO97183.1 - 4e-05 24.2 0.6 0.00012 22.7 0.1 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFO97183.1 - 4.8e-05 24.0 0.0 9.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFO97183.1 - 0.00019 22.1 0.2 0.00048 20.8 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain CheR PF01739.18 KFO97183.1 - 0.00061 19.3 0.1 0.00094 18.7 0.1 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Met_10 PF02475.16 KFO97183.1 - 0.0071 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein FmrO PF07091.11 KFO97183.1 - 0.014 15.0 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) DOT1 PF08123.13 KFO97183.1 - 0.02 14.4 1.2 0.24 10.9 1.1 2.4 1 1 0 1 1 1 0 Histone methylation protein DOT1 NTP_transf_3 PF12804.7 KFO97183.1 - 0.042 14.2 0.0 0.47 10.8 0.0 2.0 2 0 0 2 2 2 0 MobA-like NTP transferase domain WSD PF15613.6 KFO97184.1 - 7.3e-30 103.4 0.0 7.3e-30 103.4 0.0 4.7 4 3 0 4 4 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WAC_Acf1_DNA_bd PF10537.9 KFO97184.1 - 5.2e-25 87.9 0.0 5.2e-25 87.9 0.0 4.4 4 1 0 4 4 3 1 ATP-utilising chromatin assembly and remodelling N-terminal Bromodomain PF00439.25 KFO97184.1 - 2.1e-20 72.5 0.4 4.3e-20 71.6 0.4 1.5 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 KFO97184.1 - 4e-14 52.2 5.8 9.1e-14 51.1 5.8 1.7 1 0 0 1 1 1 1 PHD-finger DDT PF02791.17 KFO97184.1 - 1.1e-09 38.5 2.4 1.1e-09 38.5 2.4 2.9 3 0 0 3 3 2 1 DDT domain WHIM1 PF15612.6 KFO97184.1 - 3.2e-09 36.1 0.0 9.9e-09 34.5 0.0 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Prok-RING_1 PF14446.6 KFO97184.1 - 0.057 13.3 2.4 0.17 11.8 2.4 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.6 KFO97184.1 - 0.067 13.4 1.7 0.31 11.3 1.7 2.2 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-rbx1 PF12678.7 KFO97184.1 - 0.092 13.1 3.0 0.27 11.5 3.0 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain Zf_RING PF16744.5 KFO97184.1 - 0.11 12.6 2.0 0.41 10.8 2.0 2.0 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_2 PF13639.6 KFO97184.1 - 0.45 10.9 5.4 0.95 9.8 5.4 1.6 1 0 0 1 1 1 0 Ring finger domain Cofilin_ADF PF00241.20 KFO97185.1 - 3.1e-33 114.1 0.8 4.2e-33 113.7 0.8 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PX PF00787.24 KFO97186.1 - 4.2e-19 68.6 0.8 1.2e-14 54.3 0.1 3.3 2 1 1 3 3 3 2 PX domain Vps5 PF09325.10 KFO97186.1 - 1.1e-15 57.8 15.0 1.2e-13 51.2 11.9 2.8 2 1 0 2 2 2 1 Vps5 C terminal like BAR PF03114.18 KFO97186.1 - 9.4e-06 25.4 14.8 0.00098 18.8 10.0 2.7 3 1 0 3 3 3 2 BAR domain Eapp_C PF10238.9 KFO97187.1 - 4.6e-53 179.3 10.3 9.3e-53 178.3 10.3 1.5 1 0 0 1 1 1 1 E2F-associated phosphoprotein IBR PF01485.21 KFO97187.1 - 0.022 15.0 1.5 0.34 11.2 0.1 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain C1_4 PF07975.12 KFO97187.1 - 0.05 13.8 0.3 0.05 13.8 0.3 2.4 2 1 0 2 2 2 0 TFIIH C1-like domain Yippee-Mis18 PF03226.14 KFO97187.1 - 1.1 9.5 8.1 2.8 8.2 8.1 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly MAS20 PF02064.15 KFO97187.1 - 2.7 8.1 7.9 0.25 11.4 1.5 2.1 2 0 0 2 2 2 0 MAS20 protein import receptor MAP17 PF15807.5 KFO97187.1 - 3.6 7.8 6.9 0.57 10.4 2.6 1.8 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 UPF0547 PF10571.9 KFO97187.1 - 7.6 6.7 6.8 21 5.3 1.9 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 SPT_ssu-like PF11779.8 KFO97188.1 - 1.7e-05 24.3 0.2 2.1e-05 24.1 0.2 1.1 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like COX14 PF14880.6 KFO97188.1 - 0.081 12.8 1.1 0.087 12.7 1.1 1.0 1 0 0 1 1 1 0 Cytochrome oxidase c assembly 2OG-FeII_Oxy_3 PF13640.6 KFO97189.1 - 1.9e-15 57.5 0.0 2.1e-15 57.4 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KFO97189.1 - 7.5e-09 36.1 0.0 7.7e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PAS_3 PF08447.12 KFO97190.1 - 2.6e-20 72.5 0.2 9.8e-19 67.4 0.2 2.4 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 KFO97190.1 - 8.9e-10 38.7 0.1 3.7e-09 36.7 0.1 1.9 2 0 0 2 2 2 1 PAS domain PAS_9 PF13426.7 KFO97190.1 - 6.1e-05 23.2 0.1 0.00012 22.2 0.1 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 KFO97190.1 - 0.0033 17.4 0.0 1.6 8.7 0.0 2.5 2 0 0 2 2 2 2 PAS fold CsiV PF10972.8 KFO97190.1 - 0.0043 16.8 1.8 0.01 15.6 1.7 1.5 1 1 0 1 1 1 1 Peptidoglycan-binding protein, CsiV Kazal_2 PF07648.15 KFO97192.1 - 7e-19 67.7 33.6 1.2e-10 41.3 7.8 4.6 4 0 0 4 4 4 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFO97192.1 - 2.3e-13 49.9 19.7 4.5e-09 36.2 5.8 4.6 3 2 2 5 5 5 2 Kazal-type serine protease inhibitor domain EGF_2 PF07974.13 KFO97192.1 - 0.0012 19.2 9.0 0.0012 19.2 9.0 5.2 3 2 2 5 5 5 2 EGF-like domain EphA2_TM PF14575.6 KFO97192.1 - 0.58 11.1 2.1 0.61 11.0 0.3 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.25 KFO97194.1 - 8.5e-54 182.7 0.0 9.6e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO97194.1 - 7.1e-35 120.5 0.0 8.5e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFO97194.1 - 3.5e-09 36.4 0.0 4.9e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFO97194.1 - 0.00011 21.2 0.0 0.00014 20.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFO97194.1 - 0.00034 20.0 0.1 0.00046 19.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFO97194.1 - 0.038 13.6 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 KFO97194.1 - 0.041 13.5 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KFO97194.1 - 0.13 12.1 0.2 0.28 11.1 0.2 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFO97194.1 - 0.18 10.7 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Myosin_head PF00063.21 KFO97195.1 - 1e-267 889.9 5.0 1.3e-267 889.5 5.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KFO97195.1 - 2.8e-43 147.8 9.3 9.1e-43 146.1 1.8 3.1 3 0 0 3 3 3 2 Unconventional myosin tail, actin- and lipid-binding IQ PF00612.27 KFO97195.1 - 3.1e-06 26.5 22.8 0.0014 18.2 0.5 6.1 5 0 0 5 5 5 3 IQ calmodulin-binding motif AAA_16 PF13191.6 KFO97195.1 - 0.0086 16.5 0.0 0.028 14.8 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFO97195.1 - 0.034 14.4 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 KFO97195.1 - 0.041 13.4 0.9 2 7.9 0.0 2.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Sigma54_activat PF00158.26 KFO97195.1 - 0.06 13.1 0.0 1 9.1 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Frizzled PF01534.17 KFO97196.1 - 1.8e-93 313.1 15.9 2.1e-93 312.9 15.9 1.0 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region rve PF00665.26 KFO97197.1 - 4.7e-23 81.6 0.0 6.8e-21 74.7 0.0 2.4 2 1 0 2 2 2 2 Integrase core domain Integrase_Zn PF02022.19 KFO97197.1 - 9.2e-14 51.1 2.2 1.7e-13 50.2 0.7 2.2 2 0 0 2 2 2 1 Integrase Zinc binding domain RNase_H PF00075.24 KFO97197.1 - 1.6e-08 34.9 0.0 2.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 RNase H zf-C2H2 PF00096.26 KFO97198.1 - 5.8e-06 26.5 13.9 6.3e-05 23.2 2.3 2.3 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO97198.1 - 0.00011 22.7 11.6 0.00053 20.6 1.8 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO97198.1 - 0.00036 20.7 1.6 0.00094 19.4 0.7 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFO97198.1 - 0.00049 19.9 0.7 0.0011 18.8 0.3 1.8 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 KFO97198.1 - 0.00054 20.3 12.6 0.00072 19.9 2.6 2.6 3 0 0 3 3 3 2 Zinc-finger double domain Zn-ribbon_8 PF09723.10 KFO97198.1 - 0.0012 18.9 2.1 0.07 13.3 2.8 2.1 1 1 1 2 2 2 2 Zinc ribbon domain zf-C2H2_11 PF16622.5 KFO97198.1 - 0.029 14.1 5.3 1.1 9.1 2.0 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type XPA_N PF01286.18 KFO97198.1 - 0.064 13.3 1.4 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 XPA protein N-terminal zf-LYAR PF08790.11 KFO97198.1 - 0.19 11.6 0.7 0.19 11.6 0.7 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Snurportin1 PF11538.8 KFO97199.1 - 0.15 12.3 0.2 0.41 10.9 0.2 1.8 1 0 0 1 1 1 0 Snurportin1 Creatininase PF02633.14 KFO97201.1 - 0.32 10.4 7.2 36 3.7 0.1 4.5 2 2 2 4 4 4 0 Creatinine amidohydrolase Ion_trans_2 PF07885.16 KFO97204.1 - 9.2e-38 128.1 16.8 1.8e-18 66.3 8.7 2.9 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KFO97204.1 - 1.5e-07 30.9 3.9 0.019 14.2 0.0 2.2 1 1 0 2 2 2 2 Ion transport protein CLTH PF10607.9 KFO97204.1 - 0.081 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain IRK PF01007.20 KFO97204.1 - 0.19 11.5 4.2 0.31 10.9 0.0 2.6 2 1 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain DUF676 PF05057.14 KFO97206.1 - 1.3e-57 194.8 0.0 2.2e-57 194.1 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3657 PF12394.8 KFO97206.1 - 2e-18 66.7 3.5 5.5e-18 65.3 1.2 2.8 2 0 0 2 2 2 1 Protein FAM135 Palm_thioest PF02089.15 KFO97206.1 - 1.2e-07 31.8 0.0 2.9e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 KFO97206.1 - 1.2e-05 25.2 0.0 2.3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 KFO97206.1 - 0.0067 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Sam68-YY PF16568.5 KFO97208.1 - 5.8e-19 68.6 34.4 1.2e-18 67.6 34.4 1.5 1 0 0 1 1 1 1 Tyrosine-rich domain of Sam68 Qua1 PF16274.5 KFO97208.1 - 4.2e-07 29.7 4.1 4.2e-07 29.7 4.1 2.1 2 0 0 2 2 2 1 Qua1 domain KH_1 PF00013.29 KFO97208.1 - 4.8e-07 29.5 0.0 8.5e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 KH domain zf-H2C2_2 PF13465.6 KFO97210.1 - 4.4e-43 143.8 131.8 1.6e-07 31.4 0.3 20.9 21 1 0 21 21 21 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFO97210.1 - 9.5e-42 139.2 156.7 6.9e-05 23.1 3.3 19.4 19 0 0 19 19 19 17 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO97210.1 - 9.7e-35 116.3 149.7 0.0053 17.5 2.9 19.4 19 0 0 19 19 19 18 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFO97210.1 - 3e-27 94.0 133.3 2.5e-09 36.7 1.1 15.5 18 1 0 18 18 18 9 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KFO97210.1 - 4.9e-15 55.6 95.2 0.0014 18.9 0.7 12.3 11 1 1 12 12 12 8 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KFO97210.1 - 0.0001 22.5 5.4 0.0001 22.5 5.4 15.0 4 2 12 16 16 16 3 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFO97210.1 - 0.029 14.8 0.4 0.029 14.8 0.4 14.4 16 0 0 16 16 16 0 Zinc-finger of C2H2 type Rad50_zn_hook PF04423.14 KFO97210.1 - 0.089 12.6 0.1 0.089 12.6 0.1 4.5 4 0 0 4 4 4 0 Rad50 zinc hook motif ARS2 PF04959.13 KFO97210.1 - 0.13 12.7 0.1 0.13 12.7 0.1 5.2 5 0 0 5 5 5 0 Arsenite-resistance protein 2 Zn-C2H2_12 PF18112.1 KFO97210.1 - 0.33 11.4 24.8 2 8.9 0.3 8.4 9 0 0 9 9 9 0 Autophagy receptor zinc finger-C2H2 domain RVT_1 PF00078.27 KFO97211.1 - 0.00015 21.4 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.11 KFO97211.1 - 0.25 11.1 0.6 0.43 10.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) RVT_1 PF00078.27 KFO97213.1 - 0.069 12.7 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RAP1 PF07218.11 KFO97213.1 - 0.25 9.6 0.0 0.42 8.9 0.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Glyco_transf_29 PF00777.18 KFO97214.1 - 1.2e-77 261.0 0.1 1.3e-77 260.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) G_glu_transpept PF01019.21 KFO97214.1 - 0.0081 15.0 0.0 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Cytochrome-c551 PF10643.9 KFO97214.1 - 0.13 11.9 0.0 6.9 6.2 0.0 2.2 1 1 1 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 Ndr PF03096.14 KFO97215.1 - 7.1e-125 415.4 0.0 8.4e-125 415.1 0.0 1.0 1 0 0 1 1 1 1 Ndr family Abhydrolase_1 PF00561.20 KFO97215.1 - 0.00043 20.0 0.0 0.058 13.0 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFO97215.1 - 0.015 14.6 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 IGFBP PF00219.18 KFO97216.1 - 4.1e-11 43.4 21.0 4.1e-11 43.4 21.0 5.4 5 2 1 6 6 6 1 Insulin-like growth factor binding protein VWC PF00093.18 KFO97216.1 - 1.8e-08 34.6 12.0 1.8e-08 34.6 12.0 5.3 4 3 0 4 4 4 1 von Willebrand factor type C domain Cys_knot PF00007.22 KFO97216.1 - 2.3e-08 34.3 7.6 2.3e-08 34.3 7.6 4.3 4 2 1 5 5 5 1 Cystine-knot domain TSP_1 PF00090.19 KFO97216.1 - 2.7e-06 27.5 4.3 2.7e-06 27.5 4.3 3.9 4 0 0 4 4 4 1 Thrombospondin type 1 domain SH2 PF00017.24 KFO97217.1 - 8.8e-21 73.8 0.4 2e-20 72.6 0.1 1.7 2 0 0 2 2 2 1 SH2 domain SH3_1 PF00018.28 KFO97217.1 - 5.6e-07 29.1 0.0 1.1e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain HSBP1 PF06825.12 KFO97218.1 - 0.057 13.3 0.3 0.057 13.3 0.3 1.9 3 0 0 3 3 3 0 Heat shock factor binding protein 1 KCNQ_channel PF03520.14 KFO97219.1 - 5.4e-82 274.2 0.2 9.3e-82 273.5 0.2 1.4 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel KCNQC3-Ank-G_bd PF11956.8 KFO97219.1 - 1.1e-39 134.9 2.8 1.1e-39 134.9 2.8 1.8 2 0 0 2 2 2 1 Ankyrin-G binding motif of KCNQ2-3 Ion_trans PF00520.31 KFO97219.1 - 1.4e-28 99.8 2.3 1.6e-28 99.6 1.2 1.6 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.16 KFO97219.1 - 7.2e-13 48.3 0.3 1.8e-12 47.0 0.3 1.6 1 0 0 1 1 1 1 Ion channel Lig_chan PF00060.26 KFO97219.1 - 0.00037 20.3 0.0 0.00083 19.2 0.0 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel Phospholip_A2_1 PF00068.19 KFO97221.1 - 3.7e-52 175.5 38.5 3.5e-27 95.1 14.9 2.2 2 0 0 2 2 2 2 Phospholipase A2 DUF717 PF05338.12 KFO97221.1 - 0.0048 17.0 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF717) Guanylate_cyc PF00211.20 KFO97223.1 - 4.1e-88 293.8 0.0 3.7e-58 196.2 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 KFO97223.1 - 1.1e-34 120.4 5.4 1.1e-34 120.4 5.4 2.4 2 0 0 2 2 2 1 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF1053 PF06327.14 KFO97223.1 - 2.6e-28 98.6 0.1 6.8e-28 97.3 0.1 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) TBK1_ULD PF18396.1 KFO97223.1 - 0.0062 16.5 0.2 0.016 15.1 0.2 1.6 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain RVT_1 PF00078.27 KFO97224.1 - 0.0055 16.3 0.0 0.0087 15.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ArfGap PF01412.18 KFO97225.1 - 9.7e-36 122.4 0.0 2.9e-35 120.8 0.0 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 KFO97225.1 - 9e-27 94.3 13.0 1.7e-26 93.4 13.0 1.4 1 0 0 1 1 1 1 BAR domain of APPL family Ank_2 PF12796.7 KFO97225.1 - 1.7e-15 57.3 1.3 7.9e-09 36.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) PH PF00169.29 KFO97225.1 - 1.5e-10 41.6 0.4 6.4e-10 39.5 0.4 2.2 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.28 KFO97225.1 - 1.1e-09 37.8 0.3 2.3e-09 36.7 0.3 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFO97225.1 - 1.4e-09 37.6 0.2 3e-09 36.6 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.18 KFO97225.1 - 4.3e-09 36.4 7.7 8.4e-09 35.4 7.7 1.4 1 0 0 1 1 1 1 BAR domain Ank PF00023.30 KFO97225.1 - 6.5e-09 35.9 0.3 0.00027 21.2 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat SH3_2 PF07653.17 KFO97225.1 - 5.8e-07 29.1 0.2 1.4e-06 27.8 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain Ank_4 PF13637.6 KFO97225.1 - 2e-06 28.2 0.7 0.00044 20.8 0.2 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFO97225.1 - 5.2e-06 26.4 0.3 0.056 14.0 0.0 3.7 4 0 0 4 4 3 2 Ankyrin repeat Ank_5 PF13857.6 KFO97225.1 - 0.002 18.4 0.1 0.028 14.7 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) SKA1 PF07160.12 KFO97225.1 - 0.0059 16.5 4.3 0.5 10.2 1.0 2.7 2 0 0 2 2 2 2 Spindle and kinetochore-associated protein 1 STELLO PF03385.17 KFO97225.1 - 0.007 15.2 0.2 2.9 6.6 0.0 3.2 3 0 0 3 3 3 1 STELLO glycosyltransferases PH_3 PF14593.6 KFO97225.1 - 0.043 13.9 0.1 0.15 12.2 0.1 2.0 2 0 0 2 2 1 0 PH domain PH_9 PF15410.6 KFO97225.1 - 0.2 12.1 2.4 6.1 7.2 0.2 3.1 3 1 0 3 3 2 0 Pleckstrin homology domain DUF1394 PF07159.12 KFO97226.1 - 1.6e-142 474.2 0.0 1.8e-142 474.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) V-ATPase_H_N PF03224.14 KFO97226.1 - 0.02 14.2 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H IFRD_C PF04836.12 KFO97227.1 - 0.039 14.5 55.5 1.8e+04 -41.5 55.5 8.4 1 1 0 1 1 1 0 Interferon-related protein conserved region LRAT PF04970.13 KFO97229.1 - 6.2e-14 52.4 0.4 9.1e-06 26.0 0.2 2.4 1 1 1 2 2 2 2 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 KFO97229.1 - 0.077 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 NlpC/P60 family Pkinase PF00069.25 KFO97230.1 - 1.5e-05 24.6 0.0 1.6e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain zf-Nse PF11789.8 KFO97231.1 - 1.6e-19 69.4 2.6 2.7e-19 68.7 2.6 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KFO97231.1 - 3.9e-08 33.2 0.2 7.8e-08 32.2 0.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger U-box PF04564.15 KFO97231.1 - 0.0002 21.5 0.2 0.00056 20.0 0.2 1.8 1 1 0 1 1 1 1 U-box domain Rtf2 PF04641.12 KFO97231.1 - 0.00062 19.2 10.0 0.0028 17.1 9.2 2.0 1 1 1 2 2 2 1 Rtf2 RING-finger zf-MIZ PF02891.20 KFO97231.1 - 0.0011 18.7 1.7 0.0025 17.5 1.7 1.7 1 1 0 1 1 1 1 MIZ/SP-RING zinc finger Transferase PF02458.15 KFO97231.1 - 0.013 14.1 1.2 0.016 13.9 1.2 1.2 1 0 0 1 1 1 0 Transferase family zf-C3HC4_2 PF13923.6 KFO97231.1 - 0.017 14.9 0.2 0.051 13.4 0.2 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFO97231.1 - 0.043 14.1 0.7 0.084 13.2 0.7 1.5 1 0 0 1 1 1 0 Ring finger domain HalX PF08663.10 KFO97231.1 - 0.094 13.0 3.3 0.15 12.4 0.6 2.3 2 1 0 2 2 2 0 HalX domain Transpos_assoc PF13963.6 KFO97231.1 - 0.36 11.2 2.9 0.42 11.0 0.3 2.4 2 1 1 3 3 3 0 Transposase-associated domain ParB PF08775.10 KFO97231.1 - 3.4 8.1 12.7 2.8 8.4 0.9 2.2 1 1 1 2 2 2 0 ParB family Strumpellin PF10266.9 KFO97232.1 - 0 1658.3 18.2 0 1658.1 18.2 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin HTH_43 PF09904.9 KFO97232.1 - 0.066 13.2 0.1 0.29 11.1 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix EF-hand_9 PF14658.6 KFO97232.1 - 0.13 12.6 0.0 0.73 10.2 0.0 2.4 1 0 0 1 1 1 0 EF-hand domain SE PF08491.10 KFO97233.1 - 3.6e-115 383.8 0.1 4.7e-115 383.4 0.1 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KFO97233.1 - 2.6e-19 69.7 0.0 4.1e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFO97233.1 - 1.3e-10 41.4 0.1 0.00018 21.3 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFO97233.1 - 7.2e-05 22.9 0.1 0.00018 21.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFO97233.1 - 0.00034 21.1 0.1 0.0009 19.8 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFO97233.1 - 0.00043 19.5 0.1 0.77 8.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain TrkA_N PF02254.18 KFO97233.1 - 0.0022 18.2 0.1 0.0043 17.3 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain Thi4 PF01946.17 KFO97233.1 - 0.011 15.0 0.0 0.19 10.9 0.0 2.1 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.18 KFO97233.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KFO97233.1 - 0.011 15.3 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 KFO97233.1 - 0.015 14.6 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KFO97233.1 - 0.018 14.4 0.0 5.6 6.3 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Trp_halogenase PF04820.14 KFO97233.1 - 0.031 13.1 0.1 1.7 7.4 0.1 2.5 2 1 0 3 3 3 0 Tryptophan halogenase Sacchrp_dh_NADP PF03435.18 KFO97233.1 - 0.035 14.4 0.0 0.073 13.3 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 KFO97233.1 - 0.038 14.0 0.0 0.088 12.8 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 KFO97233.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 KFO97233.1 - 0.16 11.0 0.0 0.31 10.1 0.0 1.4 1 1 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_2 PF03446.15 KFO97233.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IMD PF08397.11 KFO97234.1 - 3.2e-79 265.3 5.0 4.3e-79 264.9 5.0 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain Gp58 PF07902.11 KFO97234.1 - 0.071 11.4 0.7 0.092 11.0 0.7 1.1 1 0 0 1 1 1 0 gp58-like protein CK2S PF15011.6 KFO97234.1 - 0.098 12.5 2.7 0.19 11.6 1.7 2.1 2 0 0 2 2 2 0 Casein Kinase 2 substrate OmpH PF03938.14 KFO97234.1 - 0.43 10.9 8.6 0.86 9.9 8.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Complex1_LYR PF05347.15 KFO97235.1 - 2.1e-13 50.1 1.5 2.1e-13 50.1 1.5 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFO97235.1 - 0.00019 22.1 0.3 0.00039 21.1 0.3 1.5 1 0 0 1 1 1 1 Complex1_LYR-like TatD_DNase PF01026.21 KFO97236.1 - 4.1e-54 183.6 0.0 5e-54 183.4 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase TRC8_N PF13705.6 KFO97237.1 - 3.4e-172 573.8 42.1 4e-172 573.6 42.1 1.0 1 0 0 1 1 1 1 TRC8 N-terminal domain zf-RING_2 PF13639.6 KFO97237.1 - 4.8e-09 36.4 8.6 4.8e-09 36.4 8.6 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFO97237.1 - 7.6e-09 35.3 7.6 7.6e-09 35.3 7.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFO97237.1 - 1.2e-07 31.9 8.3 4.8e-07 30.0 8.3 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFO97237.1 - 1.7e-06 27.8 8.0 1.7e-06 27.8 8.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFO97237.1 - 7.3e-05 22.6 8.0 7.3e-05 22.6 8.0 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KFO97237.1 - 7.6e-05 22.7 5.6 0.001 19.1 5.6 2.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KFO97237.1 - 8.5e-05 22.3 5.4 8.5e-05 22.3 5.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFO97237.1 - 9e-05 22.3 4.9 0.00022 21.0 4.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KFO97237.1 - 0.0005 19.7 6.1 0.0005 19.7 6.1 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KFO97237.1 - 0.0021 18.0 7.9 0.006 16.6 7.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_10 PF16685.5 KFO97237.1 - 0.24 11.5 3.4 0.57 10.3 3.4 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 FANCL_C PF11793.8 KFO97237.1 - 0.42 10.8 11.1 2.2 8.5 8.5 3.1 2 1 0 2 2 2 0 FANCL C-terminal domain zf-P11 PF03854.14 KFO97237.1 - 0.58 9.9 5.4 2.3 7.9 5.4 2.1 1 0 0 1 1 1 0 P-11 zinc finger FYDLN_acid PF09538.10 KFO97237.1 - 0.72 10.6 6.4 1.4 9.7 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Zf_RING PF16744.5 KFO97237.1 - 0.86 9.8 6.9 0.32 11.1 4.0 1.8 2 0 0 2 2 1 0 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 KFO97237.1 - 2.2 8.0 11.7 0.25 11.0 6.7 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type TMEM65 PF10507.9 KFO97238.1 - 2e-46 156.4 3.0 2.4e-46 156.2 3.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 65 Romo1 PF10247.9 KFO97238.1 - 0.042 14.2 1.9 0.16 12.3 0.0 2.2 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 DUF2273 PF10031.9 KFO97238.1 - 0.074 13.1 1.3 0.074 13.1 1.3 2.5 3 0 0 3 3 3 0 Small integral membrane protein (DUF2273) C2 PF00168.30 KFO97239.1 - 1.5e-71 237.2 0.2 1.3e-15 57.5 0.0 7.4 6 1 0 6 6 6 6 C2 domain Ferlin_C PF16165.5 KFO97239.1 - 6.3e-40 136.6 4.9 7.1e-38 130.0 0.2 4.4 4 2 2 6 6 6 2 Ferlin C-terminus FerB PF08150.12 KFO97239.1 - 1.2e-31 109.1 0.1 5e-31 107.1 0.1 2.2 1 0 0 1 1 1 1 FerB (NUC096) domain FerI PF08151.12 KFO97239.1 - 2.3e-19 69.2 0.0 6.6e-19 67.7 0.0 1.9 1 0 0 1 1 1 1 FerI (NUC094) domain PTPlike_phytase PF14566.6 KFO97239.1 - 0.17 12.0 0.1 0.61 10.2 0.1 1.9 1 0 0 1 1 1 0 Inositol hexakisphosphate Synaptobrevin PF00957.21 KFO97239.1 - 1.8 8.4 7.8 4.3 7.2 7.8 1.6 1 0 0 1 1 1 0 Synaptobrevin TSGP1 PF07771.11 KFO97239.1 - 7.6 6.7 6.1 4.6 7.4 0.1 2.6 2 0 0 2 2 2 0 Tick salivary peptide group 1 Annexin PF00191.20 KFO97240.1 - 1.9e-97 319.4 12.5 1.2e-25 89.3 0.1 4.0 4 0 0 4 4 4 4 Annexin Myb_DNA-bind_7 PF15963.5 KFO97240.1 - 8.8e-06 25.5 1.1 0.57 10.1 0.0 4.0 3 1 1 4 4 4 2 Myb DNA-binding like Acetyltransf_11 PF13720.6 KFO97240.1 - 0.00031 21.1 1.5 3.2 8.3 0.0 3.7 3 1 1 4 4 4 2 Udp N-acetylglucosamine O-acyltransferase; Domain 2 TSLP PF15216.6 KFO97240.1 - 0.12 12.7 2.6 16 5.8 0.0 3.7 3 1 1 4 4 4 0 Thymic stromal lymphopoietin CTK3 PF12243.8 KFO97240.1 - 0.12 12.3 1.5 14 5.7 0.0 3.1 3 1 0 3 3 3 0 CTD kinase subunit gamma CTK3 HJURP_C PF12347.8 KFO97240.1 - 0.13 12.4 0.4 0.49 10.5 0.0 2.0 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat Kelch_1 PF01344.25 KFO97241.1 - 2e-40 136.1 0.1 5e-09 35.6 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFO97241.1 - 2.3e-32 110.2 0.6 0.00015 22.0 0.0 6.8 4 2 3 7 7 7 6 Kelch motif BTB PF00651.31 KFO97241.1 - 1.5e-26 92.8 1.6 2e-26 92.4 0.2 1.9 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.6 KFO97241.1 - 2.1e-26 91.7 0.3 3.7e-05 23.7 0.0 6.6 5 1 1 6 6 6 5 Galactose oxidase, central domain BACK PF07707.15 KFO97241.1 - 2.3e-25 88.7 1.7 7.3e-25 87.1 0.3 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 KFO97241.1 - 1.5e-24 85.7 0.0 0.0048 17.2 0.0 6.8 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 KFO97241.1 - 4.9e-21 73.8 0.3 0.0033 17.3 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 KFO97241.1 - 1e-14 54.1 1.3 0.07 13.1 0.1 6.3 6 0 0 6 6 6 5 Kelch motif DUF3342 PF11822.8 KFO97241.1 - 0.0019 18.4 0.7 0.055 13.7 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3342) DUF1668 PF07893.13 KFO97241.1 - 0.071 12.4 0.1 2.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1668) Elongin_A PF06881.11 KFO97242.1 - 0.00026 21.4 0.1 0.00089 19.8 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box-like PF12937.7 KFO97242.1 - 0.0024 17.7 0.2 0.0086 16.0 0.2 2.0 1 0 0 1 1 1 1 F-box-like Pox_A8 PF04745.12 KFO97242.1 - 0.012 14.7 0.6 0.017 14.2 0.6 1.3 1 0 0 1 1 1 0 VITF-3 subunit protein F-box PF00646.33 KFO97242.1 - 0.034 14.1 0.5 0.17 11.8 0.1 2.5 2 0 0 2 2 2 0 F-box domain Nt_Gln_amidase PF09764.9 KFO97243.1 - 2.1e-64 216.5 0.0 2.4e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase AAA PF00004.29 KFO97244.1 - 5.5e-49 166.0 0.0 1.2e-41 142.2 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 KFO97244.1 - 5.5e-19 68.0 0.0 1.5e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 Bromodomain AAA_lid_3 PF17862.1 KFO97244.1 - 9.2e-13 47.8 0.2 2.4e-12 46.4 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KFO97244.1 - 1.8e-07 31.7 2.4 9.2e-05 22.9 0.1 3.8 4 1 0 4 4 3 1 AAA ATPase domain AAA_2 PF07724.14 KFO97244.1 - 1.4e-05 25.3 0.0 6.4e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KFO97244.1 - 1.8e-05 24.5 0.0 0.00043 20.1 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.14 KFO97244.1 - 0.00026 21.0 0.2 0.13 12.2 0.0 3.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFO97244.1 - 0.00029 21.1 1.9 0.036 14.3 0.1 4.5 4 1 0 4 4 4 1 AAA domain SR-25 PF10500.9 KFO97244.1 - 0.0013 18.4 2.9 0.0025 17.5 2.9 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein AAA_7 PF12775.7 KFO97244.1 - 0.0018 17.9 0.0 0.28 10.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 KFO97244.1 - 0.0027 18.2 0.0 0.036 14.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFO97244.1 - 0.0068 16.8 0.0 0.059 13.8 0.0 2.4 2 0 0 2 2 2 1 RNA helicase RuvB_N PF05496.12 KFO97244.1 - 0.012 15.3 0.0 0.11 12.3 0.0 2.6 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 KFO97244.1 - 0.016 15.0 1.2 0.43 10.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 KFO97244.1 - 0.027 13.7 0.0 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 KFO97244.1 - 0.034 13.5 0.1 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ResIII PF04851.15 KFO97244.1 - 0.049 13.6 0.0 0.3 11.1 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit IMUP PF15761.5 KFO97244.1 - 0.066 13.9 4.2 0.13 13.0 4.2 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein AAA_33 PF13671.6 KFO97244.1 - 0.067 13.4 0.0 0.35 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KFO97244.1 - 0.079 12.5 0.0 0.28 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KFO97244.1 - 0.12 12.7 0.2 0.6 10.3 0.0 2.3 2 0 0 2 2 1 0 AAA domain TIP49 PF06068.13 KFO97244.1 - 0.15 11.3 0.0 0.4 9.8 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_19 PF13245.6 KFO97244.1 - 0.19 12.1 0.0 7.3 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFO97244.1 - 0.21 11.3 0.0 1 9.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AF-4 PF05110.13 KFO97244.1 - 0.59 8.2 7.2 0.89 7.6 7.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Homeodomain PF00046.29 KFO97245.1 - 4.5e-29 100.1 9.1 6.1e-08 32.4 0.1 4.4 4 0 0 4 4 4 4 Homeodomain zf_C2H2_ZHX PF18387.1 KFO97245.1 - 3.9e-24 84.0 0.6 3.9e-24 84.0 0.6 2.3 2 0 0 2 2 2 1 Zinc-fingers and homeoboxes C2H2 finger domain Homez PF11569.8 KFO97245.1 - 6.2e-19 67.2 0.7 8.7e-12 44.3 0.3 4.3 4 0 0 4 4 4 3 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 KFO97245.1 - 1e-14 54.1 9.0 0.00085 19.2 0.2 4.9 5 0 0 5 5 5 4 Homeobox KN domain zf-C2H2_4 PF13894.6 KFO97245.1 - 6.3 7.9 5.9 4.7 8.3 0.8 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFO97245.1 - 8.1 7.1 6.7 15 6.3 0.6 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF5588 PF17826.1 KFO97246.1 - 7.1e-95 318.0 7.7 2.1e-94 316.4 7.7 1.6 1 1 0 1 1 1 1 Family of unknown function (DUF5588) ANAPC3 PF12895.7 KFO97246.1 - 0.012 15.8 0.2 4.1 7.7 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KFO97246.1 - 0.041 14.2 0.7 0.076 13.3 0.1 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFO97246.1 - 0.27 11.8 2.9 11 6.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFO97246.1 - 0.87 10.4 2.5 0.65 10.8 0.3 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFO97246.1 - 1.2 9.4 2.9 8.4 6.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat FAM83 PF07894.12 KFO97247.1 - 1.1e-101 340.0 0.1 1.3e-101 339.8 0.1 1.1 1 0 0 1 1 1 1 FAM83 A-H PLDc_2 PF13091.6 KFO97247.1 - 0.00036 20.4 0.0 0.00068 19.5 0.0 1.5 1 0 0 1 1 1 1 PLD-like domain RabGAP-TBC PF00566.18 KFO97248.1 - 6.3e-09 35.8 3.8 6.3e-09 35.8 3.8 2.8 3 0 0 3 3 3 1 Rab-GTPase-TBC domain WD40 PF00400.32 KFO97248.1 - 2.1e-06 28.4 5.3 2.8 9.0 0.6 5.6 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO97248.1 - 2e-05 24.8 0.0 2.2 8.7 0.0 4.6 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 KFO97248.1 - 0.027 13.8 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal Psu PF07455.11 KFO97248.1 - 0.42 10.2 8.9 0.19 11.3 5.8 2.1 2 0 0 2 2 2 0 Phage polarity suppression protein (Psu) DER1 PF04511.15 KFO97249.1 - 2.5e-57 193.9 9.7 2.8e-57 193.7 9.7 1.0 1 0 0 1 1 1 1 Der1-like family DUF3341 PF11821.8 KFO97249.1 - 0.042 13.5 0.3 0.086 12.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) Chitin_synth_2 PF03142.15 KFO97250.1 - 7.7e-19 67.7 2.4 1e-14 54.1 0.7 3.4 2 1 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.6 KFO97250.1 - 3.8e-18 66.2 0.0 2e-16 60.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KFO97250.1 - 5.7e-09 36.0 0.0 0.00018 21.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 KFO97250.1 - 1e-06 28.8 16.6 7.7e-06 26.0 16.6 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KFO97250.1 - 0.0015 18.0 0.0 0.0035 16.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 Tweety PF04906.13 KFO97250.1 - 0.046 12.4 0.1 0.046 12.4 0.1 1.8 2 0 0 2 2 2 0 Tweety PH_17 PF18012.1 KFO97251.1 - 2.7e-27 94.3 0.2 8.7e-27 92.6 0.1 2.0 2 0 0 2 2 2 1 PH domain PDZ PF00595.24 KFO97251.1 - 1.1e-18 67.4 0.6 2.2e-18 66.4 0.6 1.5 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 KFO97251.1 - 3.5e-15 56.4 0.0 1.2e-10 41.8 0.0 2.3 2 0 0 2 2 2 2 PH domain PDZ_6 PF17820.1 KFO97251.1 - 3.6e-05 23.5 0.1 9.5e-05 22.2 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFO97251.1 - 0.00012 22.3 0.1 0.00033 20.9 0.1 1.7 1 0 0 1 1 1 1 PDZ domain MTBP_mid PF14919.6 KFO97252.1 - 1.3e-148 494.8 0.6 2.1e-148 494.1 0.6 1.4 1 0 0 1 1 1 1 MDM2-binding MTBP_C PF14920.6 KFO97252.1 - 8.2e-123 409.1 7.9 8.2e-123 409.1 7.9 1.7 2 0 0 2 2 2 1 MDM2-binding MTBP_N PF14918.6 KFO97252.1 - 2.5e-94 315.5 0.3 4.4e-94 314.7 0.3 1.4 1 0 0 1 1 1 1 MDM2-binding AKAP2_C PF15304.6 KFO97252.1 - 0.041 13.2 4.4 0.069 12.4 4.4 1.3 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus Insulin PF00049.18 KFO97252.1 - 0.71 10.9 3.9 13 6.8 0.8 3.0 2 1 0 2 2 2 0 Insulin/IGF/Relaxin family Ribosomal_L13 PF00572.18 KFO97253.1 - 3e-07 30.7 0.1 4e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 VWA PF00092.28 KFO97254.1 - 2.1e-111 370.0 0.1 9.8e-55 185.5 0.2 2.7 2 0 0 2 2 2 2 von Willebrand factor type A domain fn3 PF00041.21 KFO97254.1 - 1.6e-94 310.4 10.7 4.1e-13 49.5 0.0 8.3 8 0 0 8 8 8 8 Fibronectin type III domain Collagen PF01391.18 KFO97254.1 - 2.5e-37 126.5 168.0 2e-08 33.8 29.9 5.5 2 2 3 5 5 5 5 Collagen triple helix repeat (20 copies) VWA_2 PF13519.6 KFO97254.1 - 1.6e-31 109.2 0.0 5.9e-17 62.3 0.0 2.9 3 0 0 3 3 3 2 von Willebrand factor type A domain DUF2369 PF10179.9 KFO97254.1 - 2.5e-07 31.0 2.3 15 6.1 0.0 6.6 7 0 0 7 7 7 1 Uncharacterised conserved protein (DUF2369) Pur_ac_phosph_N PF16656.5 KFO97254.1 - 3.9e-07 30.5 11.2 0.45 11.1 0.0 8.1 7 2 0 7 7 7 1 Purple acid Phosphatase, N-terminal domain DUF4959 PF16323.5 KFO97254.1 - 0.0024 18.2 0.2 1.5 9.1 0.0 3.9 3 1 1 4 4 4 1 Domain of unknown function (DUF4959) DEP PF00610.21 KFO97255.1 - 1.3e-46 156.5 2.0 1.6e-25 88.9 0.4 2.3 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ_6 PF17820.1 KFO97255.1 - 2e-06 27.6 0.0 3.5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFO97255.1 - 0.0097 16.2 0.0 0.025 14.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Complex1_LYR_2 PF13233.6 KFO97255.1 - 0.012 16.3 1.7 0.041 14.6 1.7 2.0 1 1 0 1 1 1 0 Complex1_LYR-like PDZ PF00595.24 KFO97255.1 - 0.084 13.2 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 PDZ domain MCM6_C PF18263.1 KFO97255.1 - 0.41 10.9 2.1 2.4 8.4 0.1 2.6 2 1 0 2 2 2 0 MCM6 C-terminal winged-helix domain Dcc1 PF09724.9 KFO97256.1 - 7.4e-94 314.8 3.5 8.6e-94 314.6 3.5 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Peptidase_M1_N PF17900.1 KFO97257.1 - 5.5e-06 26.7 0.1 7.9e-05 22.9 0.1 2.4 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 KFO97257.1 - 0.0035 16.9 1.7 0.0086 15.7 1.7 1.7 1 1 0 1 1 1 1 Peptidase family M1 domain HEAT_2 PF13646.6 KFO97257.1 - 0.0079 16.6 0.1 0.35 11.3 0.0 3.3 4 0 0 4 4 4 1 HEAT repeats PhoD_N PF16655.5 KFO97257.1 - 0.17 12.4 0.0 0.6 10.7 0.0 1.9 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain HEAT PF02985.22 KFO97257.1 - 0.41 11.0 4.2 3.7 8.1 0.0 4.1 5 0 0 5 5 5 0 HEAT repeat Phosphodiest PF01663.22 KFO97258.1 - 3.8e-77 260.3 0.0 1.5e-41 143.2 0.4 2.1 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.17 KFO97258.1 - 1.2e-15 57.7 45.0 1.1e-08 35.3 13.8 3.2 3 0 0 3 3 3 2 Somatomedin B domain Endonuclease_NS PF01223.23 KFO97258.1 - 1.3e-10 41.5 0.0 2.2e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Sulfatase PF00884.23 KFO97258.1 - 5.5e-05 22.7 0.0 0.017 14.5 0.0 2.2 2 0 0 2 2 2 2 Sulfatase MARVEL PF01284.23 KFO97259.1 - 7.9e-10 38.9 10.7 8.5e-10 38.8 10.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF3687 PF12459.8 KFO97259.1 - 0.97 9.0 7.5 0.1 12.2 1.8 2.1 1 1 1 2 2 2 0 D-Ala-teichoic acid biosynthesis protein SieB PF14163.6 KFO97259.1 - 1.6 8.2 4.0 5.3 6.5 2.8 2.0 1 1 0 1 1 1 0 Super-infection exclusion protein B DUF4227 PF14004.6 KFO97259.1 - 8.6 6.4 7.5 0.55 10.3 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4227) Lectin_C PF00059.21 KFO97260.1 - 6.7e-18 65.4 0.0 9.9e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain Collagen PF01391.18 KFO97260.1 - 5.1e-13 48.6 46.1 8.8e-08 31.8 19.5 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) TNFR_c6 PF00020.18 KFO97261.1 - 1.7e-28 98.7 36.8 2.2e-10 40.7 12.1 4.7 4 0 0 4 4 4 4 TNFR/NGFR cysteine-rich region Death PF00531.22 KFO97261.1 - 9.4e-18 64.2 3.2 1e-09 38.4 0.1 2.5 1 1 1 2 2 2 2 Death domain BCDHK_Adom3 PF10436.9 KFO97261.1 - 0.0045 16.9 3.5 0.016 15.0 3.5 1.9 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase tRNA_NucTran2_2 PF13735.6 KFO97261.1 - 0.93 9.5 4.5 3.7 7.5 0.6 2.6 1 1 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative Ephrin_rec_like PF07699.13 KFO97261.1 - 5 7.0 34.1 1 9.2 1.7 4.2 1 1 3 4 4 4 0 Putative ephrin-receptor like SAM_2 PF07647.17 KFO97262.1 - 1.2e-17 63.8 0.9 1.6e-17 63.3 0.9 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFO97262.1 - 1.5e-11 44.6 0.9 2.2e-11 44.0 0.9 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFO97262.1 - 8.8e-09 35.2 0.1 1.3e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PAPS_reduct PF01507.19 KFO97262.1 - 0.1 12.7 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Tcf25 PF04910.14 KFO97262.1 - 0.13 11.3 0.1 0.14 11.2 0.1 1.0 1 0 0 1 1 1 0 Transcriptional repressor TCF25 RVT_1 PF00078.27 KFO97263.1 - 0.1 12.1 0.0 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_transf_64 PF09258.10 KFO97264.1 - 1.5e-106 355.2 0.8 1.9e-106 354.8 0.8 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 KFO97264.1 - 4.7e-25 88.4 0.1 1.1e-24 87.3 0.0 1.6 2 0 0 2 2 2 1 Exostosin family Med30 PF11315.8 KFO97265.1 - 6.7e-66 221.0 1.6 7.7e-66 220.8 1.6 1.0 1 0 0 1 1 1 1 Mediator complex subunit 30 UPF0449 PF15136.6 KFO97265.1 - 0.12 12.8 4.4 0.31 11.5 4.4 1.9 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF948 PF06103.11 KFO97265.1 - 0.17 12.2 0.2 0.73 10.1 0.2 2.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) MetOD2 PF18548.1 KFO97265.1 - 0.26 11.4 3.7 0.14 12.2 1.5 1.7 2 0 0 2 2 2 0 Metanogen output domain 2 NYD-SP28_assoc PF14775.6 KFO97265.1 - 0.26 11.4 4.7 0.56 10.3 4.7 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain Cation_efflux PF01545.21 KFO97266.1 - 6.9e-41 140.2 16.3 9.7e-41 139.7 16.3 1.2 1 0 0 1 1 1 1 Cation efflux family PsbN PF02468.15 KFO97266.1 - 0.84 9.5 0.0 0.84 9.5 0.0 3.8 4 0 0 4 4 4 0 Photosystem II reaction centre N protein (psbN) Rad21_Rec8_N PF04825.13 KFO97267.1 - 1.7e-40 137.6 0.0 3.4e-40 136.6 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KFO97267.1 - 7.4e-23 79.6 0.2 3.5e-22 77.4 0.1 2.2 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 KFO97267.1 - 0.0013 18.7 0.1 0.0013 18.7 0.1 1.8 2 0 0 2 2 2 1 Segregation and condensation protein ScpA Fcf1 PF04900.12 KFO97268.1 - 1.5e-28 99.1 0.0 3.5e-28 97.9 0.0 1.6 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KFO97268.1 - 0.039 14.3 0.0 0.13 12.5 0.0 1.9 1 1 0 1 1 1 0 PIN like domain JAB PF01398.21 KFO97269.1 - 3.2e-20 72.3 0.3 3.2e-20 72.3 0.3 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TnpV PF14198.6 KFO97269.1 - 0.18 11.8 2.0 2.2 8.3 0.2 2.7 3 0 0 3 3 3 0 Transposon-encoded protein TnpV RVT_1 PF00078.27 KFO97270.1 - 0.0051 16.4 0.0 0.0082 15.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFO97271.1 - 0.043 13.3 0.0 0.075 12.5 0.0 1.4 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) GATA PF00320.27 KFO97272.1 - 2.5e-12 46.2 5.7 2.5e-12 46.2 5.7 2.7 2 0 0 2 2 2 1 GATA zinc finger zf_C2H2_ZHX PF18387.1 KFO97272.1 - 0.00028 20.5 32.2 0.24 11.1 0.8 7.4 6 1 1 7 7 7 4 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_5 PF13909.6 KFO97272.1 - 0.0074 16.0 2.3 0.0074 16.0 2.3 8.2 8 0 0 8 8 8 4 C2H2-type zinc-finger domain Zap1_zf2 PF18217.1 KFO97272.1 - 0.18 11.9 3.7 0.59 10.2 0.2 3.6 3 0 0 3 3 3 0 Zap1 zinc finger 2 Actin_micro PF17003.5 KFO97272.1 - 0.39 9.9 22.0 5.2 6.2 0.2 5.4 4 1 0 4 4 4 0 Putative actin-like family DUF5472 PF17566.2 KFO97272.1 - 1.1 9.3 4.0 41 4.2 0.1 4.5 5 1 1 6 6 6 0 Family of unknown function (DUF5472) DUF2024 PF09630.10 KFO97272.1 - 5.7 6.9 8.1 1.1 9.2 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF2024) RVT_1 PF00078.27 KFO97273.1 - 0.1 12.1 0.0 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pentapeptide_4 PF13599.6 KFO97274.1 - 0.098 12.8 0.0 0.18 12.0 0.0 1.6 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) zf-H2C2_2 PF13465.6 KFO97275.1 - 2.5e-08 34.0 9.4 0.00041 20.7 2.3 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFO97275.1 - 1.4e-06 28.4 2.1 1.4e-06 28.4 2.1 1.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf_UBZ PF18439.1 KFO97275.1 - 0.00056 19.5 0.6 0.00078 19.0 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 KFO97275.1 - 0.00096 18.9 2.7 0.0015 18.2 2.6 1.4 1 1 0 1 1 1 1 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KFO97275.1 - 0.0043 17.8 2.6 0.0043 17.8 2.6 1.5 2 0 0 2 2 2 1 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFO97275.1 - 0.01 16.0 3.8 0.012 15.7 3.8 1.3 1 0 0 1 1 1 0 Zinc ribbon domain zf-C2H2_6 PF13912.6 KFO97275.1 - 0.023 14.7 3.6 0.037 14.0 3.6 1.5 1 1 0 1 1 1 0 C2H2-type zinc finger XPA_N PF01286.18 KFO97275.1 - 0.054 13.5 2.6 0.074 13.1 2.6 1.4 1 0 0 1 1 1 0 XPA protein N-terminal 7tm_4 PF13853.6 KFO97276.1 - 3.6e-22 79.4 5.0 4.1e-22 79.2 5.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO97276.1 - 0.0022 17.3 4.7 0.0028 17.0 4.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FtsJ PF01728.19 KFO97277.1 - 1.5e-28 100.1 0.0 1.3e-26 93.8 0.0 2.3 2 0 0 2 2 2 2 FtsJ-like methyltransferase PNP_UDP_1 PF01048.20 KFO97278.1 - 1e-47 162.4 0.0 1.1e-47 162.2 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily EF-hand_1 PF00036.32 KFO97279.1 - 7.1e-21 72.1 2.9 1.6e-06 27.2 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFO97279.1 - 2.6e-19 69.4 1.9 2.6e-10 40.6 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFO97279.1 - 8.5e-19 65.8 1.7 4.7e-06 26.1 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFO97279.1 - 1.2e-15 56.2 1.4 0.0011 18.3 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KFO97279.1 - 8e-06 25.6 1.2 0.011 15.6 0.2 3.2 1 1 1 2 2 2 2 EF-hand domain pair Dockerin_1 PF00404.18 KFO97279.1 - 0.00073 19.7 0.0 2.5 8.4 0.0 2.8 3 0 0 3 3 3 2 Dockerin type I domain EF-hand_10 PF14788.6 KFO97279.1 - 0.004 17.0 1.9 6.2 6.8 0.3 3.8 3 1 1 4 4 4 2 EF hand GPHH PF16905.5 KFO97279.1 - 0.18 11.6 0.0 4.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated Aminotran_1_2 PF00155.21 KFO97280.1 - 1.5e-93 313.9 0.0 1.7e-93 313.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aa_trans PF01490.18 KFO97281.1 - 1.3e-55 188.8 24.1 1.6e-55 188.5 24.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KFO97281.1 - 2.8e-07 29.9 22.1 6.2e-07 28.8 15.9 2.3 2 0 0 2 2 2 2 Tryptophan/tyrosine permease family Spore_permease PF03845.13 KFO97281.1 - 0.11 11.4 23.7 0.013 14.4 6.1 2.5 3 0 0 3 3 3 0 Spore germination protein Rubis-subs-bind PF09273.11 KFO97282.1 - 1.4e-17 64.5 3.6 3e-17 63.5 3.6 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 KFO97282.1 - 6.1e-14 52.7 0.1 2.3e-13 50.9 0.0 1.8 2 0 0 2 2 2 1 SET domain RNA_pol_Rpo13 PF12136.8 KFO97282.1 - 0.11 12.4 0.2 0.11 12.4 0.2 2.6 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain Agouti PF05039.12 KFO97283.1 - 4.6e-20 72.1 17.3 7.4e-20 71.5 17.3 1.6 1 1 0 1 1 1 1 Agouti protein vATP-synt_AC39 PF01992.16 KFO97284.1 - 9.8e-104 347.5 0.5 1.1e-103 347.3 0.5 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Nab2p_Zf1 PF18260.1 KFO97284.1 - 0.05 13.5 0.6 0.26 11.2 0.0 2.3 2 0 0 2 2 2 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 adh_short PF00106.25 KFO97285.1 - 1.2e-41 142.3 0.0 1.7e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFO97285.1 - 3.3e-26 92.3 0.0 4.6e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFO97285.1 - 0.0051 16.7 0.0 0.0071 16.3 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFO97285.1 - 0.076 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) FH2 PF02181.23 KFO97286.1 - 2e-84 283.9 5.1 2.8e-84 283.4 5.1 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain Formin_GBD_N PF18382.1 KFO97286.1 - 1e-11 45.1 0.0 2.3e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Formin N-terminal GTPase-binding domain Na_H_Exchanger PF00999.21 KFO97287.1 - 1.8e-84 283.7 38.7 2.2e-84 283.5 38.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NEXCaM_BD PF16644.5 KFO97287.1 - 2.1e-06 27.9 2.6 4.7e-06 26.8 2.6 1.5 1 0 0 1 1 1 1 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin PIG-H PF10181.9 KFO97287.1 - 0.97 9.3 5.8 0.097 12.5 0.6 2.0 2 0 0 2 2 2 0 GPI-GlcNAc transferase complex, PIG-H component p25-alpha PF05517.12 KFO97289.1 - 4.4e-66 221.8 9.1 5e-66 221.6 9.1 1.0 1 0 0 1 1 1 1 p25-alpha DnaB PF00772.21 KFO97289.1 - 0.0097 16.0 0.0 0.015 15.3 0.0 1.6 1 1 0 1 1 1 1 DnaB-like helicase N terminal domain DHHC PF01529.20 KFO97290.1 - 2e-31 108.9 8.7 2e-31 108.9 8.7 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase EGF_CA PF07645.15 KFO97291.1 - 4.3e-19 68.5 31.9 9.2e-08 32.2 8.4 4.0 3 2 1 4 4 4 3 Calcium-binding EGF domain EGF PF00008.27 KFO97291.1 - 8.2e-12 45.2 18.5 6e-08 32.8 7.7 4.3 4 0 0 4 4 4 2 EGF-like domain hEGF PF12661.7 KFO97291.1 - 2.4e-08 34.3 15.6 5.3e-06 26.9 6.1 4.6 4 0 0 4 4 4 2 Human growth factor-like EGF cEGF PF12662.7 KFO97291.1 - 9.3e-08 31.9 0.6 9.3e-08 31.9 0.6 3.9 4 0 0 4 4 4 2 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFO97291.1 - 2e-06 27.9 5.8 2e-06 27.9 5.8 3.7 3 0 0 3 3 3 2 Coagulation Factor Xa inhibitory site EGF_2 PF07974.13 KFO97291.1 - 0.00025 21.4 11.2 0.00025 21.4 11.2 3.7 3 0 0 3 3 3 2 EGF-like domain EGF_3 PF12947.7 KFO97291.1 - 0.0056 16.8 20.9 0.3 11.3 0.0 3.7 3 0 0 3 3 3 2 EGF domain Lectin_C PF00059.21 KFO97292.1 - 1.5e-18 67.5 0.4 3.1e-18 66.5 0.4 1.5 1 0 0 1 1 1 1 Lectin C-type domain CAP PF00188.26 KFO97292.1 - 1.5e-16 61.4 0.1 3.1e-16 60.4 0.1 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family tRNA-synt_2c PF01411.19 KFO97293.1 - 1.6e-208 693.8 0.0 2.7e-208 693.0 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KFO97293.1 - 5.6e-17 61.6 0.0 1.3e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KFO97293.1 - 8.2e-17 61.9 1.6 1.5e-16 61.1 0.3 2.1 1 1 1 2 2 2 1 DHHA1 domain Med11 PF10280.9 KFO97293.1 - 0.021 15.3 0.1 0.073 13.5 0.0 1.9 2 0 0 2 2 2 0 Mediator complex protein Lipase_GDSL_3 PF14606.6 KFO97293.1 - 0.041 14.0 0.1 0.09 12.9 0.1 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Syntaxin-6_N PF09177.11 KFO97293.1 - 0.066 13.8 1.8 0.18 12.3 1.8 1.7 1 0 0 1 1 1 0 Syntaxin 6, N-terminal LINES_N PF14694.6 KFO97293.1 - 0.16 11.4 0.2 0.26 10.7 0.2 1.2 1 0 0 1 1 1 0 Lines N-terminus Spc7 PF08317.11 KFO97293.1 - 0.22 10.4 3.0 0.4 9.5 3.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein adh_short PF00106.25 KFO97294.1 - 6.9e-14 51.8 0.0 7.8e-10 38.5 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFO97294.1 - 1.6e-07 31.2 0.0 2.2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NADH_B2 PF14813.6 KFO97296.1 - 0.029 14.2 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 FAM176 PF14851.6 KFO97296.1 - 0.14 11.8 1.4 0.15 11.7 1.4 1.1 1 0 0 1 1 1 0 FAM176 family zf-H2C2_2 PF13465.6 KFO97297.1 - 1.2e-50 167.7 95.0 1e-08 35.2 0.6 11.3 11 0 0 11 11 11 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFO97297.1 - 8e-34 114.2 102.2 8.8e-05 22.7 1.1 11.3 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO97297.1 - 5.3e-26 89.1 96.8 0.0048 17.6 2.7 11.3 11 0 0 11 11 11 10 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFO97297.1 - 1.6e-16 59.7 87.6 1.1e-06 28.3 0.6 10.6 11 0 0 11 11 11 5 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFO97297.1 - 8.6e-10 38.6 58.3 0.042 14.1 0.1 11.1 11 0 0 11 11 11 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFO97297.1 - 0.0061 16.9 1.3 0.0061 16.9 1.3 9.7 11 0 0 11 11 10 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFO97297.1 - 0.021 14.8 1.6 0.021 14.8 1.6 11.0 11 2 0 11 11 10 0 C2H2-type zinc finger C1_1 PF00130.22 KFO97297.1 - 0.49 10.3 43.8 0.34 10.8 0.9 7.7 3 2 6 9 9 9 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf_UBZ PF18439.1 KFO97297.1 - 1.3 8.6 0.0 1.3 8.6 0.0 6.9 8 1 0 8 8 8 0 Ubiquitin-Binding Zinc Finger GAGA PF09237.11 KFO97297.1 - 1.6 8.6 31.0 3.6 7.5 0.1 7.9 1 1 9 10 10 10 0 GAGA factor zf-C2H2_2 PF12756.7 KFO97297.1 - 2.9 8.3 61.6 2.4 8.6 7.0 7.5 1 1 4 6 6 6 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 KFO97297.1 - 6.7 7.5 43.9 5.4 7.8 0.9 6.0 2 1 4 6 6 6 0 zinc-ribbon family adh_short PF00106.25 KFO97298.1 - 1.2e-22 80.3 0.0 7.1e-22 77.8 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFO97298.1 - 2.2e-18 66.7 0.0 4.3e-17 62.5 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFO97298.1 - 6.6e-05 22.9 0.0 9.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KFO97299.1 - 1.6e-12 47.3 0.1 9.3e-08 31.8 0.2 2.5 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFO97299.1 - 0.00057 19.5 0.1 0.0017 18.0 0.0 1.7 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase WD40 PF00400.32 KFO97300.1 - 7.2e-08 33.0 0.1 0.37 11.7 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.8 KFO97300.1 - 0.05 12.3 0.1 0.17 10.5 0.1 1.9 1 1 0 1 1 1 0 Nucleoporin Nup120/160 HPS3_N PF14761.6 KFO97300.1 - 0.079 12.5 0.0 5.3 6.5 0.0 2.6 2 1 1 3 3 3 0 Hermansky-Pudlak syndrome 3 NDUFV3 PF15880.5 KFO97301.1 - 5.8e-14 51.8 0.9 1.1e-13 51.0 0.9 1.5 1 0 0 1 1 1 1 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial Meis_PKNOX_N PF16493.5 KFO97302.1 - 2.2e-36 124.0 0.1 4.1e-36 123.2 0.1 1.5 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 Homeobox_KN PF05920.11 KFO97302.1 - 9.7e-11 41.4 1.0 2e-10 40.4 0.2 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 KFO97302.1 - 0.0071 16.2 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Homeodomain GHBP PF12772.7 KFO97302.1 - 0.2 11.1 3.0 0.19 11.2 1.8 1.6 1 1 0 1 1 1 0 Growth hormone receptor binding CBS PF00571.28 KFO97303.1 - 1e-08 35.5 0.0 1.5e-05 25.3 0.0 2.2 2 0 0 2 2 2 2 CBS domain Poxvirus_B22R_C PF13168.6 KFO97303.1 - 0.009 15.5 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 1 Poxvirus B22R protein C-terminal PALP PF00291.25 KFO97304.1 - 3.9e-16 59.3 0.0 4.1e-16 59.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Glyco_tran_WecB PF03808.13 KFO97304.1 - 0.019 14.9 0.0 0.034 14.1 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family PA-IIL PF07472.11 KFO97304.1 - 0.097 13.0 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Fucose-binding lectin II (PA-IIL) Methyltransf_16 PF10294.9 KFO97304.1 - 0.14 11.9 0.2 0.16 11.7 0.2 1.1 1 0 0 1 1 1 0 Lysine methyltransferase PALP PF00291.25 KFO97305.1 - 0.02 14.3 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme zf-CCCH PF00642.24 KFO97306.1 - 5.2e-14 51.7 17.1 8.2e-07 28.8 3.3 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KFO97306.1 - 6e-07 29.2 0.0 1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 KFO97306.1 - 2.1e-06 28.4 2.1 0.05 14.3 0.1 2.4 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KFO97306.1 - 1.5e-05 24.9 14.4 0.0099 15.9 2.9 2.5 2 0 0 2 2 2 2 Zinc finger domain KMP11 PF03037.16 KFO97306.1 - 0.0083 16.9 0.5 0.48 11.2 0.3 2.2 2 0 0 2 2 2 1 Kinetoplastid membrane protein 11 Nup35_RRM_2 PF14605.6 KFO97306.1 - 0.04 13.9 0.1 0.071 13.1 0.1 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCCH_3 PF15663.5 KFO97306.1 - 0.053 13.7 5.5 1.1 9.5 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger containing family CART PF06373.11 KFO97306.1 - 0.63 10.3 3.7 2.4 8.4 0.6 3.0 3 1 1 4 4 4 0 Cocaine and amphetamine regulated transcript protein (CART) Crystallin PF00525.18 KFO97307.1 - 2.4e-27 94.9 1.4 4.1e-27 94.1 1.4 1.4 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal HSP20 PF00011.21 KFO97307.1 - 9.3e-24 83.5 0.0 1.1e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Pkinase PF00069.25 KFO97308.1 - 4.8e-76 255.6 0.1 1.3e-75 254.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO97308.1 - 1.4e-40 139.2 0.0 2.5e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFO97308.1 - 8.8e-08 31.8 0.0 1.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFO97308.1 - 1.7e-06 27.3 0.1 3.2e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFO97308.1 - 0.091 12.1 0.6 0.18 11.1 0.6 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CCCAP PF15964.5 KFO97309.1 - 0.0015 16.9 5.5 0.005 15.2 4.3 1.9 2 0 0 2 2 2 1 Centrosomal colon cancer autoantigen protein family VHS PF00790.19 KFO97309.1 - 0.0069 16.2 0.1 0.51 10.2 0.0 2.6 2 0 0 2 2 2 1 VHS domain DUF383 PF04063.14 KFO97309.1 - 0.0076 15.9 0.2 0.016 14.9 0.2 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF383) RasGEF_N_2 PF14663.6 KFO97309.1 - 0.0098 16.3 0.7 0.073 13.5 0.1 2.5 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Exonuc_VII_L PF02601.15 KFO97309.1 - 0.019 14.6 1.0 0.025 14.1 1.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit YabA PF06156.13 KFO97309.1 - 0.022 15.4 5.3 0.08 13.6 5.1 2.1 1 1 0 1 1 1 0 Initiation control protein YabA ATP-synt_I PF03899.15 KFO97309.1 - 0.13 12.7 0.1 0.33 11.4 0.0 1.6 1 1 0 1 1 1 0 ATP synthase I chain DUF1664 PF07889.12 KFO97309.1 - 0.36 10.9 6.4 5.7 7.0 0.2 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Mis14 PF08641.12 KFO97309.1 - 0.37 11.1 8.4 0.065 13.6 4.3 1.8 2 0 0 2 2 2 0 Kinetochore protein Mis14 like Atg14 PF10186.9 KFO97309.1 - 0.6 9.1 7.5 1.1 8.3 5.1 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.14 KFO97309.1 - 0.77 9.5 7.6 0.14 12.0 3.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 KFO97309.1 - 1 9.4 13.9 0.064 13.4 8.8 1.6 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus PEP-utilisers_N PF05524.13 KFO97309.1 - 1.6 8.9 5.9 2.7 8.2 3.4 2.2 1 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal YlqD PF11068.8 KFO97309.1 - 2 8.8 9.5 0.43 10.9 5.7 1.9 2 0 0 2 2 2 0 YlqD protein Lectin_N PF03954.14 KFO97309.1 - 2 8.1 7.4 4.5 7.0 3.8 2.8 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain STAT_alpha PF01017.20 KFO97309.1 - 2.5 8.0 12.1 3.9 7.3 9.6 2.2 1 1 0 2 2 2 0 STAT protein, all-alpha domain FlaC_arch PF05377.11 KFO97309.1 - 4.2 7.8 5.9 3.4 8.1 0.8 3.1 3 1 0 3 3 2 0 Flagella accessory protein C (FlaC) LPP PF04728.13 KFO97309.1 - 8.2 6.9 7.3 1.4 9.4 0.3 3.0 4 0 0 4 4 3 0 Lipoprotein leucine-zipper DUF4201 PF13870.6 KFO97309.1 - 8.7 6.0 16.7 0.21 11.3 9.3 2.0 3 0 0 3 3 2 0 Domain of unknown function (DUF4201) Nop52 PF05997.12 KFO97310.1 - 1.1e-63 215.0 2.7 1.1e-63 215.0 2.7 1.8 2 0 0 2 2 2 1 Nucleolar protein,Nop52 Phos_pyr_kin PF08543.12 KFO97311.1 - 5.7e-06 25.9 0.3 2.2e-05 24.0 0.3 1.9 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KFO97311.1 - 0.00081 18.8 0.0 0.0036 16.6 0.0 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HpcH_HpaI PF03328.14 KFO97311.1 - 0.0057 15.8 0.0 0.013 14.6 0.0 1.6 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family SRR1 PF07985.12 KFO97311.1 - 0.0085 16.1 0.1 0.04 14.0 0.0 2.1 2 0 0 2 2 2 1 SRR1 Latrophilin PF02354.16 KFO97313.1 - 1.7e-106 356.5 10.5 2.8e-106 355.8 10.5 1.3 1 0 0 1 1 1 1 Latrophilin Cytoplasmic C-terminal region OLF PF02191.16 KFO97313.1 - 3.6e-85 285.5 5.2 6.9e-85 284.6 5.2 1.5 1 0 0 1 1 1 1 Olfactomedin-like domain 7tm_2 PF00002.24 KFO97313.1 - 1.6e-70 237.2 19.4 2.3e-70 236.7 19.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GAIN PF16489.5 KFO97313.1 - 9.8e-54 182.0 4.6 1.5e-53 181.4 4.6 1.3 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Gal_Lectin PF02140.18 KFO97313.1 - 4.1e-23 81.6 0.7 4.1e-23 81.6 0.7 2.2 2 0 0 2 2 2 1 Galactose binding lectin domain GPS PF01825.21 KFO97313.1 - 7e-16 58.5 7.3 1.7e-15 57.2 7.3 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif HRM PF02793.22 KFO97313.1 - 6.2e-07 29.6 0.7 2e-06 28.0 0.7 1.9 1 0 0 1 1 1 1 Hormone receptor domain Dicty_CAR PF05462.11 KFO97313.1 - 0.0035 16.5 14.6 0.0065 15.6 14.6 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Pox_A14 PF05767.12 KFO97313.1 - 1.3 9.2 5.5 3.7 7.8 2.1 2.8 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 HLH PF00010.26 KFO97314.1 - 1e-06 28.6 0.2 2.8e-06 27.2 0.2 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Acetyltransf_1 PF00583.25 KFO97315.1 - 3.5e-14 53.0 0.0 4.4e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFO97315.1 - 1.4e-09 38.3 0.1 1.9e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFO97315.1 - 6.3e-09 35.9 0.0 7.9e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFO97315.1 - 1.9e-05 24.8 0.1 2.9e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFO97315.1 - 0.0002 21.3 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KFO97315.1 - 0.0011 19.1 0.0 0.0019 18.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KFO97315.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KFO97315.1 - 0.025 15.2 0.0 0.032 14.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Nudix_hydro PF18290.1 KFO97315.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.6 1 1 0 1 1 1 0 Nudix hydrolase domain ATP-synt_ab PF00006.25 KFO97316.1 - 6.3e-103 343.0 0.0 7.8e-103 342.7 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.6 KFO97316.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zn_ribbon_SprT PF17283.2 KFO97317.1 - 0.00032 20.5 3.2 0.18 11.8 1.1 3.3 3 1 0 3 3 3 2 SprT-like zinc ribbon domain Yippee-Mis18 PF03226.14 KFO97317.1 - 0.0028 17.8 0.6 0.012 15.8 0.4 2.0 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SelR PF01641.18 KFO97317.1 - 0.011 15.8 0.1 0.036 14.2 0.1 1.8 1 1 0 1 1 1 0 SelR domain TackOD1 PF18551.1 KFO97317.1 - 0.23 11.1 2.7 6.6 6.4 0.1 2.3 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 DUF4379 PF14311.6 KFO97317.1 - 0.31 11.4 0.0 0.31 11.4 0.0 2.6 2 1 1 3 3 3 0 Probable Zinc-ribbon domain NTP_transf_7 PF07984.12 KFO97318.1 - 1.7e-155 517.1 0.6 1.9e-155 516.9 0.6 1.0 1 0 0 1 1 1 1 Nucleotidyltransferase Hemerythrin PF01814.23 KFO97318.1 - 0.04 14.5 0.0 0.074 13.7 0.0 1.4 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain CRAL_TRIO_2 PF13716.6 KFO97319.1 - 2.5e-32 111.9 1.5 4.3e-32 111.1 1.5 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Macro PF01661.21 KFO97319.1 - 3e-26 91.8 0.0 5.3e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Macro domain CRAL_TRIO PF00650.20 KFO97319.1 - 1.5e-07 31.2 0.8 3.7e-07 30.0 0.8 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain Epimerase_2 PF02350.19 KFO97319.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase WD40 PF00400.32 KFO97320.1 - 1e-55 184.4 20.9 5.9e-09 36.4 0.1 10.9 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.12 KFO97320.1 - 1.6e-21 76.6 0.3 3.4e-21 75.6 0.3 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KFO97320.1 - 2.2e-19 69.6 5.2 0.00016 21.9 0.0 8.5 4 3 6 10 10 10 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFO97320.1 - 4.8e-08 32.7 0.0 0.01 15.2 0.0 4.0 3 1 2 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 KFO97320.1 - 5.6e-06 25.5 2.1 4.8 6.0 0.0 6.6 3 1 5 8 8 8 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFO97320.1 - 0.024 13.3 1.5 4.3 5.9 0.0 4.2 5 0 0 5 5 5 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KFO97320.1 - 0.067 11.9 2.9 4.8 5.8 0.0 3.6 4 1 0 4 4 4 0 Nup133 N terminal like PapD-like PF14874.6 KFO97321.1 - 1.4e-10 41.3 0.0 1.8e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Flagellar-associated PapD-like T-box PF00907.22 KFO97322.1 - 5.4e-79 264.7 0.0 7.7e-79 264.2 0.0 1.2 1 0 0 1 1 1 1 T-box tRNA-synt_1b PF00579.25 KFO97323.1 - 9.7e-69 231.9 0.0 1.2e-68 231.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Occludin_ELL PF07303.13 KFO97323.1 - 0.14 12.9 0.1 3 8.6 0.0 2.3 2 0 0 2 2 2 0 Occludin homology domain FMN_dh PF01070.18 KFO97324.1 - 2e-131 438.2 0.0 2.9e-131 437.6 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KFO97324.1 - 1.4e-07 30.9 1.2 5.9e-07 28.8 0.8 1.9 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFO97324.1 - 5.3e-05 22.5 0.2 7.7e-05 22.0 0.2 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KFO97324.1 - 0.0034 16.9 0.2 0.014 14.9 0.1 1.9 1 1 1 2 2 2 1 Histidine biosynthesis protein Dus PF01207.17 KFO97324.1 - 0.0092 15.1 0.5 1.4 7.9 0.1 2.5 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) ThiG PF05690.14 KFO97324.1 - 0.053 12.8 0.3 1.5 8.1 0.1 2.3 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG Glyco_hydro_47 PF01532.20 KFO97325.1 - 2.1e-157 524.7 0.0 2.6e-157 524.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Apolipoprotein PF01442.18 KFO97325.1 - 2.9 7.7 6.3 0.98 9.3 2.9 1.8 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain C2-set_2 PF08205.12 KFO97326.1 - 1.3e-06 28.3 0.1 2.7e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 KFO97326.1 - 1.6e-05 25.4 0.3 0.0019 18.8 0.1 2.3 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFO97326.1 - 0.0031 17.7 0.4 0.031 14.4 0.1 2.1 2 0 0 2 2 2 1 Immunoglobulin V-set domain C1-set PF07654.15 KFO97326.1 - 0.0059 17.0 1.6 0.071 13.5 0.0 2.6 2 1 0 2 2 2 1 Immunoglobulin C1-set domain I-set PF07679.16 KFO97326.1 - 0.006 16.6 0.1 0.35 11.0 0.1 2.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 KFO97326.1 - 0.063 13.5 0.2 14 5.9 0.0 2.5 2 1 0 2 2 2 0 Immunoglobulin domain ANF_receptor PF01094.28 KFO97327.1 - 1.3e-108 363.3 0.0 1.6e-108 362.9 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 KFO97327.1 - 4.4e-65 219.7 30.9 8e-65 218.9 30.9 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 KFO97327.1 - 1.5e-17 63.3 11.9 4.2e-17 61.9 11.9 1.9 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.6 KFO97327.1 - 3.3e-12 46.8 0.0 1.5e-10 41.3 0.0 2.7 2 1 0 2 2 2 1 Periplasmic binding protein Ephrin_rec_like PF07699.13 KFO97327.1 - 0.019 14.7 8.8 0.058 13.2 8.8 1.8 1 0 0 1 1 1 0 Putative ephrin-receptor like DUF2614 PF11023.8 KFO97327.1 - 1.5 8.9 6.4 0.3 11.2 0.8 2.6 2 0 0 2 2 2 0 Zinc-ribbon containing domain Cystatin PF00031.21 KFO97328.1 - 1.1e-14 54.5 0.2 1.2e-14 54.3 0.2 1.0 1 0 0 1 1 1 1 Cystatin domain Dynein_light PF01221.18 KFO97328.1 - 0.086 13.2 0.2 0.11 12.9 0.2 1.2 1 0 0 1 1 1 0 Dynein light chain type 1 Cystatin PF00031.21 KFO97329.1 - 1.8e-11 44.1 0.1 1.9e-11 44.1 0.1 1.0 1 0 0 1 1 1 1 Cystatin domain Cid2 PF09774.9 KFO97330.1 - 6.7e-14 52.6 4.3 1.6e-12 48.1 4.3 2.0 1 1 0 1 1 1 1 Caffeine-induced death protein 2 FOXP-CC PF16159.5 KFO97330.1 - 0.93 10.2 5.6 21 5.8 2.9 2.2 1 1 1 2 2 2 0 FOXP coiled-coil domain DUF1075 PF06388.11 KFO97331.1 - 1e-43 148.3 0.1 1.3e-43 147.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1075) MLTD_N PF06474.12 KFO97331.1 - 0.095 12.9 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 MltD lipid attachment motif Arm PF00514.23 KFO97332.1 - 6.7e-88 286.4 17.5 1.8e-13 50.0 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KFO97332.1 - 4.7e-27 94.3 6.0 9.2e-27 93.3 6.0 1.5 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 KFO97332.1 - 4.4e-23 80.6 3.3 5.6e-23 80.3 1.5 2.1 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.6 KFO97332.1 - 2.9e-17 62.9 0.0 8.1e-07 29.3 0.0 4.8 2 1 4 6 6 6 4 HEAT repeats HEAT_EZ PF13513.6 KFO97332.1 - 1.7e-13 50.7 7.9 2.3e-05 24.8 0.0 5.9 3 2 3 6 6 6 4 HEAT-like repeat HEAT PF02985.22 KFO97332.1 - 2.1e-11 43.0 6.9 0.0024 18.0 0.0 7.6 9 1 0 9 9 8 3 HEAT repeat V-ATPase_H_C PF11698.8 KFO97332.1 - 2.6e-05 24.3 0.3 0.092 12.9 0.1 3.9 3 3 1 4 4 4 2 V-ATPase subunit H RICTOR_V PF14668.6 KFO97332.1 - 3.5e-05 23.9 0.8 0.29 11.4 0.0 4.8 4 1 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.13 KFO97332.1 - 0.00027 20.5 0.3 0.66 9.4 0.1 3.2 3 1 1 4 4 4 2 Armadillo-like DUF3361 PF11841.8 KFO97332.1 - 0.002 18.1 0.7 10 6.1 0.1 3.7 3 1 0 3 3 3 1 Domain of unknown function (DUF3361) V-ATPase_H_N PF03224.14 KFO97332.1 - 0.0028 17.0 0.3 0.96 8.7 0.0 3.3 2 1 0 3 3 3 1 V-ATPase subunit H Atx10homo_assoc PF09759.9 KFO97332.1 - 0.025 14.6 0.1 0.46 10.5 0.0 2.6 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.16 KFO97332.1 - 2.6 9.0 8.0 11 7.1 0.3 5.0 6 1 0 6 6 5 0 PBS lyase HEAT-like repeat F-box_4 PF15966.5 KFO97333.1 - 3e-42 143.2 0.3 3e-42 143.2 0.3 2.1 2 0 0 2 2 2 1 F-box zf-TRAF_2 PF15965.5 KFO97333.1 - 4.6e-40 136.0 21.6 4.6e-40 136.0 21.6 3.0 3 0 0 3 3 3 1 TRAF-like zinc-finger F-box-like PF12937.7 KFO97333.1 - 0.0023 17.8 0.1 0.0065 16.3 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFO97333.1 - 0.0029 17.4 0.3 0.0098 15.8 0.3 1.9 1 0 0 1 1 1 1 F-box domain ASC PF00858.24 KFO97334.1 - 2.6e-108 362.8 14.0 3.3e-108 362.5 14.0 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Spin-Ssty PF02513.17 KFO97335.1 - 1.2e-76 252.3 7.8 6.5e-28 96.2 0.2 3.1 3 0 0 3 3 3 3 Spin/Ssty Family GETHR PF05671.11 KFO97336.1 - 0.0013 18.0 36.5 0.8 9.1 9.6 3.7 1 1 2 3 3 3 3 GETHR pentapeptide repeat (5 copies) zf-MIZ PF02891.20 KFO97337.1 - 3.4e-23 81.1 4.5 3.4e-23 81.1 4.5 2.3 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KFO97337.1 - 6e-06 26.0 1.2 6e-06 26.0 1.2 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Pro_isomerase PF00160.21 KFO97338.1 - 1.4e-46 158.7 0.2 1.5e-46 158.5 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PLAC9 PF15205.6 KFO97339.1 - 1.3e-07 31.9 0.0 1.3e-07 31.9 0.0 1.0 1 0 0 1 1 1 1 Placenta-specific protein 9 PALP PF00291.25 KFO97340.1 - 6e-60 203.1 0.2 7.5e-60 202.8 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.25 KFO97340.1 - 0.0071 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 KFO97340.1 - 0.0073 16.3 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 ACT domain DUF4499 PF14934.6 KFO97341.1 - 5.5e-30 103.5 8.2 6e-30 103.4 8.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) RIBIOP_C PF04950.12 KFO97342.1 - 1.3e-95 320.2 0.0 1.3e-95 320.2 0.0 2.4 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KFO97342.1 - 1.8e-31 108.0 0.0 1e-30 105.6 0.0 2.4 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 KFO97342.1 - 5e-06 26.2 0.0 0.00054 19.5 0.0 3.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFO97342.1 - 0.00091 19.3 0.1 0.0068 16.5 0.1 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFO97342.1 - 0.0048 17.3 0.0 0.022 15.1 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KFO97342.1 - 0.026 14.9 0.1 0.026 14.9 0.1 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KFO97342.1 - 0.047 14.1 0.1 0.31 11.4 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 KFO97342.1 - 0.051 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Gly_acyl_tr_C PF08444.10 KFO97342.1 - 0.056 13.7 0.0 0.28 11.5 0.0 2.2 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region ABC_tran PF00005.27 KFO97342.1 - 1.1 9.7 0.0 1.1 9.7 0.0 3.1 3 0 0 3 3 3 0 ABC transporter CAP PF00188.26 KFO97343.1 - 4.8e-22 79.1 0.6 6.2e-22 78.8 0.6 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family BLOC1_2 PF10046.9 KFO97344.1 - 0.0048 17.2 0.2 0.039 14.3 0.0 2.0 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 AIP3 PF03915.13 KFO97344.1 - 0.039 13.0 0.4 0.056 12.5 0.4 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 DUF1993 PF09351.10 KFO97344.1 - 0.11 12.6 0.0 0.72 10.0 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) DUF1664 PF07889.12 KFO97344.1 - 0.16 12.0 0.2 0.85 9.7 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PDZ PF00595.24 KFO97345.1 - 1.4e-10 41.4 0.0 2.1e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PB1 PF00564.24 KFO97345.1 - 2.5e-10 40.1 0.0 5.6e-10 39.0 0.0 1.6 2 0 0 2 2 2 1 PB1 domain PDZ_6 PF17820.1 KFO97345.1 - 3.3e-09 36.4 0.0 6.4e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFO97345.1 - 0.12 12.7 0.1 0.26 11.6 0.1 1.5 1 0 0 1 1 1 0 PDZ domain PL48 PF15903.5 KFO97346.1 - 7.9e-172 571.0 2.8 5e-170 565.1 2.8 2.3 1 1 0 1 1 1 1 Filopodia upregulated, FAM65 HEAT_2 PF13646.6 KFO97346.1 - 1.4e-05 25.4 3.5 0.00012 22.5 0.1 2.9 2 1 1 3 3 3 1 HEAT repeats Arm PF00514.23 KFO97346.1 - 0.019 15.0 3.9 4.2 7.6 0.0 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HR1 PF02185.16 KFO97346.1 - 0.2 11.8 0.1 0.2 11.8 0.1 2.6 3 0 0 3 3 3 0 Hr1 repeat Geminin PF07412.12 KFO97347.1 - 3.2e-76 255.5 8.3 3.5e-76 255.4 8.3 1.0 1 0 0 1 1 1 1 Geminin UPF0242 PF06785.11 KFO97347.1 - 0.0022 18.1 7.1 0.0029 17.7 7.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Phage_GPO PF05929.11 KFO97347.1 - 0.0073 16.0 2.2 0.009 15.7 2.2 1.1 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase FapA PF03961.13 KFO97347.1 - 0.0098 14.5 3.8 0.011 14.4 3.8 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A Csm1_N PF18504.1 KFO97347.1 - 0.023 15.0 1.9 0.023 15.0 1.9 2.3 2 1 0 2 2 2 0 Csm1 N-terminal domain UvsY PF11056.8 KFO97347.1 - 0.043 14.2 3.5 0.1 12.9 1.4 2.0 1 1 1 2 2 2 0 Recombination, repair and ssDNA binding protein UvsY DivIC PF04977.15 KFO97347.1 - 0.048 13.4 1.5 0.048 13.4 1.5 2.0 1 1 1 2 2 2 0 Septum formation initiator Fzo_mitofusin PF04799.13 KFO97347.1 - 0.14 11.7 1.7 0.2 11.2 1.7 1.3 1 0 0 1 1 1 0 fzo-like conserved region ZapD PF07072.11 KFO97347.1 - 0.19 11.5 3.4 0.67 9.7 0.2 2.0 1 1 1 2 2 2 0 Cell division protein CCDC-167 PF15188.6 KFO97347.1 - 0.22 11.9 9.8 0.5 10.7 9.8 1.8 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF5101 PF17031.5 KFO97347.1 - 0.31 11.2 8.3 0.084 13.0 2.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5101) XLF PF09302.11 KFO97347.1 - 0.31 11.2 3.5 0.25 11.5 1.1 1.8 1 1 1 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Laminin_II PF06009.12 KFO97347.1 - 0.6 10.1 5.4 0.088 12.8 1.0 1.8 2 0 0 2 2 2 0 Laminin Domain II Val_tRNA-synt_C PF10458.9 KFO97347.1 - 0.61 10.4 11.1 2 8.7 0.7 2.7 2 1 1 3 3 3 0 Valyl tRNA synthetase tRNA binding arm DUF641 PF04859.12 KFO97347.1 - 2.5 8.5 8.2 14 6.0 8.5 1.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) CRA PF06589.11 KFO97347.1 - 2.5 8.2 11.5 5.5 7.1 11.5 1.5 1 1 0 1 1 1 0 Circumsporozoite-related antigen (CRA) DUF4566 PF15130.6 KFO97348.1 - 8.7e-139 460.3 2.3 9.7e-139 460.2 2.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4566) 4HBT PF03061.22 KFO97349.1 - 4.9e-14 52.4 0.3 8.5e-14 51.7 0.1 1.5 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_3 PF13622.6 KFO97349.1 - 7.4e-05 23.1 0.1 9e-05 22.8 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.6 KFO97349.1 - 0.007 16.5 0.2 0.038 14.1 0.1 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4442) UBA_4 PF14555.6 KFO97350.1 - 1.9e-09 37.2 0.0 3.4e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain Exo_endo_phos PF03372.23 KFO97350.1 - 1.3e-08 34.7 0.0 2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family 7tm_1 PF00001.21 KFO97351.1 - 6.9e-58 196.0 16.1 8.3e-58 195.8 16.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFO97351.1 - 1.6e-08 34.2 14.0 2e-08 33.9 14.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 KFO97351.1 - 3.3e-08 33.2 14.2 7.9e-06 25.4 14.2 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 KFO97351.1 - 2.3e-05 23.9 12.2 3e-05 23.5 12.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srd PF10317.9 KFO97351.1 - 6.2e-05 22.3 19.2 0.0033 16.7 19.2 2.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7tm_4 PF13853.6 KFO97351.1 - 0.00012 21.9 14.5 0.00028 20.7 14.5 1.5 1 1 0 1 1 1 1 Olfactory receptor Chitin_synth_1 PF01644.17 KFO97351.1 - 0.018 15.0 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Chitin synthase Bac_rhodopsin PF01036.18 KFO97351.1 - 0.44 10.1 12.4 0.32 10.5 6.0 2.4 2 1 0 2 2 2 0 Bacteriorhodopsin-like protein Myelin_MBP PF01669.17 KFO97352.1 - 7e-70 234.5 9.3 1.1e-69 233.9 9.3 1.3 1 0 0 1 1 1 1 Myelin basic protein zf-H2C2_2 PF13465.6 KFO97353.1 - 1.8e-72 236.8 95.2 3e-10 40.0 0.4 13.5 13 1 0 13 13 13 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFO97353.1 - 1.3e-61 201.8 91.1 5.3e-07 29.7 1.2 12.1 11 1 1 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO97353.1 - 2.3e-53 174.2 90.2 0.00012 22.6 0.3 12.2 11 1 1 12 12 12 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO97353.1 - 1e-31 108.6 54.6 0.00015 21.9 3.8 12.1 11 1 1 12 12 12 8 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFO97353.1 - 5e-12 45.4 61.2 0.00095 18.9 0.4 10.5 11 1 1 12 12 12 6 zinc-finger C2H2-type zf-Di19 PF05605.12 KFO97353.1 - 8.4e-10 38.8 64.3 0.00013 22.2 3.8 8.6 4 2 3 8 8 8 7 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KFO97353.1 - 1.1e-09 38.0 90.4 0.0029 17.5 0.9 12.1 11 1 1 12 12 11 7 C2H2-type zinc finger zf-met PF12874.7 KFO97353.1 - 1e-07 32.1 68.7 0.066 13.6 0.3 11.3 10 1 1 11 11 11 4 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFO97353.1 - 6.2e-07 29.7 59.6 0.17 12.3 2.3 10.8 1 1 11 12 12 12 5 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 KFO97353.1 - 1.6e-05 24.5 7.9 0.0021 17.8 1.0 16.6 13 5 1 14 14 13 4 C2H2-type zinc-finger domain TRAF6_Z2 PF18048.1 KFO97353.1 - 0.0004 20.4 40.9 0.086 13.0 0.3 9.9 8 2 1 9 9 9 2 TNF receptor-associated factor 6 zinc finger 2 zinc_ribbon_15 PF17032.5 KFO97353.1 - 0.0021 18.8 48.0 11 6.9 4.4 6.4 2 1 3 5 5 5 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 KFO97353.1 - 0.012 15.7 47.5 0.62 10.2 0.6 8.7 5 2 3 9 9 9 0 Zinc ribbon domain zinc_ribbon_9 PF14369.6 KFO97353.1 - 0.038 14.2 50.2 0.57 10.5 0.3 10.1 12 0 0 12 12 11 0 zinc-ribbon zf-C2HE PF16278.5 KFO97353.1 - 0.052 14.0 0.0 0.052 14.0 0.0 10.6 7 3 5 12 12 11 0 C2HE / C2H2 / C2HC zinc-binding finger GAGA PF09237.11 KFO97353.1 - 0.33 10.8 23.7 0.38 10.6 0.2 6.4 2 2 5 7 7 7 0 GAGA factor FYDLN_acid PF09538.10 KFO97353.1 - 0.49 11.1 21.0 4.5 8.0 0.7 6.9 5 3 1 6 6 6 0 Protein of unknown function (FYDLN_acid) zf_UBZ PF18439.1 KFO97353.1 - 0.76 9.4 0.1 0.76 9.4 0.1 9.9 12 0 0 12 12 12 0 Ubiquitin-Binding Zinc Finger zf-CHCC PF10276.9 KFO97353.1 - 0.98 9.5 0.1 0.98 9.5 0.1 8.7 11 0 0 11 11 10 0 Zinc-finger domain zf-C2H2 PF00096.26 KFO97354.1 - 5.3e-26 89.6 86.1 0.00011 22.5 4.3 10.7 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO97354.1 - 5.7e-20 70.3 81.9 0.0048 17.6 0.7 11.0 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFO97354.1 - 7.7e-09 35.6 2.2 7.7e-09 35.6 2.2 12.7 14 1 0 14 14 14 4 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFO97354.1 - 2.6e-06 27.1 2.0 2.6e-06 27.1 2.0 8.2 8 0 0 8 8 8 4 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KFO97354.1 - 4.6e-05 23.6 37.3 0.61 10.4 0.3 6.5 5 2 1 6 6 6 5 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_ZHX PF18387.1 KFO97354.1 - 0.057 13.1 0.2 0.057 13.1 0.2 6.1 6 2 1 7 7 7 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 KFO97354.1 - 0.19 12.1 50.4 0.066 13.5 0.4 7.7 5 2 3 8 8 8 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 KFO97354.1 - 0.38 11.5 21.3 0.22 12.2 4.5 6.1 6 1 1 7 7 7 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_8 PF15909.5 KFO97354.1 - 0.67 10.3 0.0 0.67 10.3 0.0 5.7 5 1 1 6 6 6 0 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 KFO97354.1 - 1.7 8.7 39.5 0.14 12.1 2.0 7.1 7 0 0 7 7 7 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 KFO97355.1 - 5.7e-13 49.1 19.0 0.0053 17.1 1.0 5.5 4 2 1 5 5 5 4 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KFO97355.1 - 1.3e-10 41.2 28.9 0.038 14.5 1.3 5.6 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO97355.1 - 1.1e-09 38.3 23.7 0.069 14.0 2.8 5.7 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFO97355.1 - 4.7e-05 23.3 21.8 0.024 14.6 2.4 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2HE PF16278.5 KFO97355.1 - 0.00027 21.3 11.6 2.2 8.8 0.0 6.0 5 0 0 5 5 5 2 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 KFO97355.1 - 0.0031 17.8 9.3 0.023 15.1 1.9 2.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF760 PF05542.11 KFO97355.1 - 0.031 14.6 0.4 0.47 10.8 0.0 3.2 4 0 0 4 4 3 0 Protein of unknown function (DUF760) Lar_restr_allev PF14354.6 KFO97355.1 - 0.043 14.2 1.7 16 6.0 0.0 4.5 6 0 0 6 6 6 0 Restriction alleviation protein Lar zf-C2H2_jaz PF12171.8 KFO97355.1 - 0.043 14.1 0.8 0.043 14.1 0.8 4.9 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KFO97355.1 - 0.049 13.7 11.1 6.4 7.0 0.1 5.6 5 0 0 5 5 5 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 KFO97355.1 - 0.07 13.1 1.8 0.075 13.0 0.2 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PyrI_C PF02748.15 KFO97355.1 - 0.37 10.7 2.1 4.1 7.4 0.1 3.3 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_11 PF16622.5 KFO97355.1 - 1.1 9.1 15.8 0.13 12.0 2.4 3.8 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 KFO97355.1 - 3.7 7.5 8.6 4.5 7.2 0.2 4.2 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) ADH_zinc_N PF00107.26 KFO97356.1 - 1.3e-26 93.1 0.0 2.3e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFO97356.1 - 1e-14 55.7 0.0 4.2e-14 53.7 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFO97356.1 - 2.9e-09 36.8 0.1 8.8e-06 25.6 0.0 3.3 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KFO97356.1 - 0.00079 19.3 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase DUF3318 PF11780.8 KFO97356.1 - 0.2 11.6 0.2 2.6 8.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3318) zf-H2C2_2 PF13465.6 KFO97357.1 - 9.5e-35 117.5 46.5 2e-07 31.1 0.9 7.1 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFO97357.1 - 1.9e-12 46.9 51.5 0.00011 22.4 2.0 7.3 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFO97357.1 - 2.2e-12 46.5 43.7 1.4e-06 28.0 2.3 7.1 7 0 0 7 7 7 4 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KFO97357.1 - 8.8e-07 29.3 47.5 0.0013 19.3 1.8 7.3 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFO97357.1 - 0.22 11.5 0.1 0.22 11.5 0.1 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF3268 PF11672.8 KFO97357.1 - 0.84 10.0 6.4 9.4 6.6 2.0 2.7 2 0 0 2 2 2 0 zinc-finger-containing domain zf_C2H2_ZHX PF18387.1 KFO97357.1 - 3.7 7.3 17.4 2.3 7.9 1.3 4.6 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 KFO97357.1 - 4.6 7.6 19.5 0.84 10.0 1.2 5.0 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFO97357.1 - 5.9 6.7 9.6 1.9 8.3 0.3 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type VPDSG-CTERM PF18205.1 KFO97357.1 - 8.6 6.3 8.9 0.36 10.7 0.8 2.7 3 0 0 3 3 3 0 VPDSG-CTERM motif Actin_micro PF17003.5 KFO97357.1 - 9.8 5.2 11.7 4.5 6.4 0.2 4.1 1 1 2 3 3 3 0 Putative actin-like family CysA_C_terminal PF17850.1 KFO97358.1 - 0.12 12.9 5.2 1.2e+02 3.4 5.2 3.5 1 1 0 1 1 1 0 CysA C-terminal regulatory domain zf-H2C2_2 PF13465.6 KFO97359.1 - 1.7e-07 31.3 7.8 3.5e-05 24.0 1.1 15.0 17 0 0 17 17 17 8 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFO97359.1 - 2.5e-05 23.9 2.7 2.5e-05 23.9 2.7 12.7 13 0 0 13 13 13 6 C2H2-type zinc-finger domain zf-met PF12874.7 KFO97359.1 - 0.0052 17.1 2.4 0.0052 17.1 2.4 7.9 9 0 0 9 9 9 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFO97359.1 - 0.011 16.1 0.6 0.011 16.1 0.6 13.4 7 6 6 14 14 14 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KFO97359.1 - 0.021 15.3 1.6 0.021 15.3 1.6 17.4 19 0 0 19 19 19 0 Zinc finger, C2H2 type Peptidase_M20 PF01546.28 KFO97360.1 - 3.4e-37 128.2 0.0 4.3e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFO97360.1 - 1.3e-16 60.4 0.0 4.1e-16 58.8 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KFO97360.1 - 0.033 13.9 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 DUF4708 PF15813.5 KFO97361.1 - 9.3e-28 97.1 0.3 1e-27 97.0 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4708) Cyt-b5 PF00173.28 KFO97362.1 - 4.9e-08 33.0 0.0 6.6e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TIM21 PF08294.11 KFO97363.1 - 1.3e-47 161.3 0.3 1.5e-47 161.1 0.3 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 KFO97363.1 - 1.4e-05 24.8 0.1 4.2e-05 23.3 0.1 1.7 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 F-box-like PF12937.7 KFO97364.1 - 8.1e-11 41.7 0.0 1.6e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFO97364.1 - 5.3e-08 32.6 0.0 1.1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KFO97364.1 - 0.069 13.0 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 F-box CUB PF00431.20 KFO97365.1 - 3.5e-39 133.5 0.6 1.3e-25 89.9 0.0 2.7 3 0 0 3 3 3 2 CUB domain Ldl_recept_a PF00057.18 KFO97365.1 - 1.4e-07 31.6 2.4 1.4e-07 31.6 2.4 2.8 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A C1q PF00386.21 KFO97366.1 - 2e-28 99.1 0.3 2.3e-28 98.9 0.3 1.0 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 KFO97366.1 - 0.014 15.3 0.1 0.025 14.5 0.1 1.4 1 1 0 1 1 1 0 BclA C-terminal domain RVT_1 PF00078.27 KFO97367.1 - 0.0055 16.3 0.0 0.0087 15.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SH2 PF00017.24 KFO97369.1 - 1.9e-12 47.1 0.0 4.9e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.16 KFO97369.1 - 3.8e-11 43.2 2.6 4.1e-11 43.1 1.2 1.8 2 0 0 2 2 2 1 SOCS box Yae1_N PF09811.9 KFO97370.1 - 1.8e-12 46.7 39.2 1.2e+04 -3.9 39.2 4.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal RTTN_N PF14726.6 KFO97371.1 - 1.2e-30 106.1 11.8 1.7e-30 105.7 0.0 6.0 7 0 0 7 7 7 1 Rotatin, an armadillo repeat protein, centriole functioning Trehalase_Ca-bi PF07492.11 KFO97371.1 - 0.2 11.4 0.3 0.46 10.3 0.3 1.6 1 0 0 1 1 1 0 Neutral trehalase Ca2+ binding domain IRS PF02174.17 KFO97372.1 - 3.5e-30 103.9 0.0 5.9e-30 103.1 0.0 1.3 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.29 KFO97372.1 - 0.0016 18.9 0.5 0.0031 18.0 0.5 1.5 1 0 0 1 1 1 1 PH domain CREPT PF16566.5 KFO97372.1 - 0.055 13.6 0.4 0.17 12.0 0.2 1.8 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Thioredoxin_6 PF13848.6 KFO97374.1 - 7.5e-28 97.7 0.2 1.6e-25 90.1 0.7 2.2 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 KFO97374.1 - 1.8e-25 88.9 0.0 2.1e-24 85.5 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_2 PF13098.6 KFO97374.1 - 0.00027 21.3 0.2 0.0038 17.7 0.1 2.8 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFO97374.1 - 0.0079 16.5 0.1 2.4 8.5 0.0 3.7 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin_7 PF13899.6 KFO97374.1 - 0.051 13.8 0.2 0.31 11.2 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like Transglut_C PF00927.22 KFO97375.1 - 5.1e-31 106.9 0.0 1.3e-17 63.9 0.0 2.6 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 KFO97375.1 - 2.8e-12 47.1 0.1 5.8e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Sulfotransfer_1 PF00685.27 KFO97376.1 - 4.5e-13 49.3 0.0 4.5e-12 46.0 0.0 2.8 2 1 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFO97376.1 - 5.1e-07 30.3 0.0 4.8e-05 23.8 0.0 3.3 3 1 0 3 3 3 1 Sulfotransferase family DUF4962 PF16332.5 KFO97376.1 - 5.3e-05 21.9 5.1 5.3e-05 21.9 5.1 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4962) RVT_1 PF00078.27 KFO97377.1 - 0.067 12.7 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Cadherin PF00028.17 KFO97380.1 - 3.6e-86 283.7 7.9 7.6e-20 71.2 0.1 5.2 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFO97380.1 - 1.2e-55 187.8 0.1 2.3e-55 186.9 0.1 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.12 KFO97380.1 - 2.5e-06 27.2 0.0 0.96 9.3 0.0 4.6 4 1 0 4 4 4 2 Cadherin-like Cadherin_3 PF16184.5 KFO97380.1 - 1.8e-05 24.7 5.1 0.96 9.5 0.0 5.0 5 0 0 5 5 5 3 Cadherin-like RET_CLD1 PF17756.1 KFO97380.1 - 0.1 12.9 0.0 6.5 7.1 0.0 2.8 2 0 0 2 2 2 0 RET Cadherin like domain 1 Cadherin_4 PF17803.1 KFO97380.1 - 0.68 10.6 18.4 1.7 9.3 0.3 4.6 4 0 0 4 4 4 0 Bacterial cadherin-like domain Invasin_D3 PF09134.10 KFO97380.1 - 9.2 6.7 9.7 26 5.2 0.6 4.4 3 1 0 4 4 4 0 Invasin, domain 3 7tm_1 PF00001.21 KFO97381.1 - 3.4e-34 118.4 23.5 1.2e-32 113.3 23.5 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFO97381.1 - 1.7e-11 44.0 15.7 4.6e-09 36.0 15.7 2.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFO97381.1 - 2.7e-08 33.9 18.3 7.3e-06 25.9 18.3 2.1 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFO97381.1 - 0.00011 21.9 23.2 0.0061 16.2 22.0 3.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx GPR_Gpa2_C PF11970.8 KFO97381.1 - 0.11 12.6 0.3 0.11 12.6 0.3 2.1 2 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 KFO97382.1 - 3.3e-36 125.0 37.4 9.8e-35 120.1 37.4 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFO97382.1 - 1.8e-13 50.9 27.8 2.7e-11 43.7 23.1 2.9 1 1 1 2 2 2 2 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KFO97382.1 - 1.8e-09 37.4 38.2 3.9e-09 36.3 38.2 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFO97382.1 - 0.23 11.1 43.2 1 8.9 39.5 2.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Pox_MCEL PF03291.16 KFO97383.1 - 2e-108 362.5 2.6 2.6e-108 362.1 2.6 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 KFO97383.1 - 9.9e-12 45.4 0.0 2.1e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFO97383.1 - 1.1e-10 41.5 0.1 2.1e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFO97383.1 - 1.9e-08 34.8 0.0 4.1e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFO97383.1 - 1.9e-06 28.5 0.0 4.3e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFO97383.1 - 2.5e-06 27.4 0.0 5.2e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KFO97383.1 - 0.0047 16.8 0.1 0.0089 15.9 0.1 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_32 PF13679.6 KFO97383.1 - 0.0082 16.1 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KFO97383.1 - 0.026 13.7 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family MTS PF05175.14 KFO97383.1 - 0.026 14.1 0.0 0.066 12.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain DUF1279 PF06916.13 KFO97384.1 - 3.5e-24 85.1 0.3 3.5e-24 85.1 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1279) Apolipoprotein PF01442.18 KFO97384.1 - 2.9e-05 24.0 0.4 4.4e-05 23.4 0.4 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain LEA_4 PF02987.16 KFO97384.1 - 4.8e-05 23.4 11.6 4.8e-05 23.4 11.6 1.7 1 1 0 1 1 1 1 Late embryogenesis abundant protein YtxH PF12732.7 KFO97384.1 - 0.00012 22.6 10.3 0.0002 21.8 9.4 1.8 2 0 0 2 2 2 1 YtxH-like protein DctP PF03480.13 KFO97384.1 - 0.026 13.9 0.3 0.04 13.3 0.3 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 FUN14 PF04930.15 KFO97384.1 - 0.029 14.8 0.0 0.052 14.0 0.0 1.4 1 0 0 1 1 1 0 FUN14 family Mit_KHE1 PF10173.9 KFO97384.1 - 0.03 14.4 1.1 0.049 13.7 1.1 1.3 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF3810 PF12725.7 KFO97384.1 - 0.037 13.4 0.1 0.043 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF883 PF05957.13 KFO97384.1 - 0.077 13.6 0.9 0.15 12.7 0.9 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Phasin PF05597.11 KFO97384.1 - 0.46 10.5 3.7 0.83 9.7 3.7 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Mt_ATP-synt_D PF05873.12 KFO97384.1 - 0.83 9.5 9.8 14 5.5 7.7 2.3 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF1664 PF07889.12 KFO97384.1 - 1.2 9.2 5.2 2.4 8.2 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Oleosin PF01277.17 KFO97384.1 - 2 8.2 3.6 2.5 7.9 1.2 2.4 2 1 0 2 2 2 0 Oleosin m04gp34like PF12216.8 KFO97385.1 - 0.098 12.2 0.9 0.23 11.0 0.6 1.7 2 0 0 2 2 2 0 Immune evasion protein Shisa PF13908.6 KFO97385.1 - 0.11 12.8 0.2 0.11 12.8 0.2 1.9 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF4834 PF16118.5 KFO97385.1 - 0.18 12.8 2.2 0.28 12.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) PspB PF06667.12 KFO97385.1 - 0.2 11.7 0.3 0.33 11.0 0.3 1.3 1 0 0 1 1 1 0 Phage shock protein B TMEM154 PF15102.6 KFO97385.1 - 0.31 11.0 0.8 0.65 9.9 0.8 1.5 1 0 0 1 1 1 0 TMEM154 protein family ASH PF15780.5 KFO97386.1 - 3.2e-17 62.5 4.1 0.00021 21.4 0.0 7.9 8 2 1 9 9 9 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 KFO97386.1 - 1.7e-11 44.2 0.9 2.5 8.4 0.0 7.0 6 1 0 6 6 6 4 Transmembrane protein 131-like MYCBPAP PF14646.6 KFO97386.1 - 4.4e-10 39.1 0.0 0.0011 18.0 0.0 4.0 4 0 0 4 4 4 3 MYCBP-associated protein family Motile_Sperm PF00635.26 KFO97386.1 - 8.4e-06 25.6 0.5 0.081 12.8 0.0 5.3 5 0 0 5 5 5 1 MSP (Major sperm protein) domain DUF1573 PF07610.11 KFO97386.1 - 0.001 19.0 2.0 1.1 9.3 0.0 4.6 5 1 0 5 5 5 2 Protein of unknown function (DUF1573) Transglut_C PF00927.22 KFO97386.1 - 0.0074 16.4 0.2 1.4 9.1 0.0 4.2 5 1 0 5 5 5 1 Transglutaminase family, C-terminal ig like domain WD40 PF00400.32 KFO97389.1 - 4.9e-10 39.9 23.7 0.00017 22.3 1.9 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO97389.1 - 1.8e-05 24.9 6.3 0.021 15.1 0.3 3.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFO97389.1 - 0.0013 17.8 2.8 0.24 10.3 0.0 2.9 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Y_phosphatase PF00102.27 KFO97390.1 - 1.9e-77 260.0 0.1 2.2e-77 259.8 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFO97390.1 - 0.007 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFO97390.1 - 0.018 15.0 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PAC2 PF09754.9 KFO97391.1 - 9.4e-40 136.9 0.0 1.1e-39 136.6 0.0 1.1 1 0 0 1 1 1 1 PAC2 family CEP76-C2 PF15627.6 KFO97392.1 - 4.6e-62 208.3 0.0 8.7e-62 207.4 0.0 1.5 1 0 0 1 1 1 1 CEP76 C2 domain Transglut_core PF01841.19 KFO97392.1 - 0.011 16.2 0.0 0.024 15.1 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily TAF PF02969.17 KFO97392.1 - 0.069 13.3 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) KIND PF16474.5 KFO97393.1 - 2.9e-47 161.0 1.7 7.6e-47 159.7 0.4 2.2 2 0 0 2 2 2 1 Kinase non-catalytic C-lobe domain FYVE PF01363.21 KFO97393.1 - 0.12 12.5 14.5 0.3 11.2 14.5 1.7 1 1 0 1 1 1 0 FYVE zinc finger PRELI PF04707.14 KFO97394.1 - 3.7e-54 182.8 0.1 4.5e-54 182.5 0.1 1.1 1 0 0 1 1 1 1 PRELI-like family PDGLE PF13190.6 KFO97394.1 - 0.036 14.0 0.1 0.067 13.1 0.1 1.5 1 0 0 1 1 1 0 PDGLE domain Rep_2 PF01719.17 KFO97394.1 - 0.093 12.5 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Plasmid replication protein Peptidase_M41 PF01434.18 KFO97395.1 - 4.8e-66 222.3 0.0 8e-66 221.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KFO97395.1 - 2.1e-42 144.7 0.0 4.4e-42 143.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFO97395.1 - 9.2e-16 57.4 0.0 2.4e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KFO97395.1 - 2.4e-10 40.7 0.1 9.5e-10 38.8 0.1 2.1 1 0 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.6 KFO97395.1 - 0.00015 22.1 0.0 0.061 13.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFO97395.1 - 0.00097 19.1 0.0 0.0038 17.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFO97395.1 - 0.0016 18.6 0.0 0.0042 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KFO97395.1 - 0.0023 18.3 0.3 0.14 12.6 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KFO97395.1 - 0.0032 17.2 0.0 0.013 15.2 0.0 2.1 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KFO97395.1 - 0.006 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KFO97395.1 - 0.039 13.7 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 KFO97395.1 - 0.073 13.2 0.3 0.41 10.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 KFO97395.1 - 0.087 12.2 0.3 0.28 10.5 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KFO97395.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KFO97395.1 - 0.21 11.0 0.5 0.64 9.4 0.2 1.8 2 0 0 2 2 2 0 PhoH-like protein Tubulin PF00091.25 KFO97396.1 - 6.4e-71 238.6 0.0 1.1e-70 237.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFO97396.1 - 6e-42 142.8 0.1 1e-41 142.0 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KFO97396.1 - 2.5e-06 27.8 0.0 7.9e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KFO97396.1 - 0.0096 15.6 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KFO97396.1 - 0.025 13.8 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 Tubulin like Endothelin PF00322.17 KFO97397.1 - 0.1 12.3 1.3 0.27 10.9 1.3 1.7 1 0 0 1 1 1 0 Endothelin family CIDE-N PF02017.15 KFO97398.1 - 4.3e-30 103.6 0.0 7.9e-30 102.7 0.0 1.4 1 0 0 1 1 1 1 CIDE-N domain BRCT_2 PF16589.5 KFO97398.1 - 0.091 13.2 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain FAD_binding_4 PF01565.23 KFO97398.1 - 0.099 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain GCV_T PF01571.21 KFO97398.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain Inositol_P PF00459.25 KFO97399.1 - 3.6e-76 256.3 0.1 3.9e-76 256.1 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family TMF_TATA_bd PF12325.8 KFO97401.1 - 0.0009 19.4 10.2 0.073 13.3 1.4 2.4 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding PRKG1_interact PF15898.5 KFO97401.1 - 0.00093 20.1 11.8 0.00093 20.1 11.8 1.9 1 1 1 2 2 2 1 cGMP-dependent protein kinase interacting domain Jnk-SapK_ap_N PF09744.9 KFO97401.1 - 0.0011 19.3 18.2 0.089 13.0 5.6 2.1 1 1 1 2 2 2 2 JNK_SAPK-associated protein-1 TMF_DNA_bd PF12329.8 KFO97401.1 - 0.0038 17.2 23.6 0.068 13.2 5.9 2.7 3 0 0 3 3 3 2 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 KFO97401.1 - 0.0041 16.9 3.3 0.0041 16.9 3.3 3.0 2 2 0 2 2 2 1 Septum formation initiator NRBF2 PF08961.10 KFO97401.1 - 0.03 13.9 0.7 0.03 13.9 0.7 2.1 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator GAS PF13851.6 KFO97401.1 - 0.032 13.6 16.3 0.14 11.4 4.2 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3452 PF11934.8 KFO97401.1 - 0.032 13.8 0.4 0.18 11.4 0.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF3452) Arc_PepC_II PF06847.11 KFO97401.1 - 0.038 14.5 1.9 0.41 11.2 0.0 2.3 2 1 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II PsbQ PF05757.11 KFO97401.1 - 0.076 12.7 0.3 0.076 12.7 0.3 1.6 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) JAKMIP_CC3 PF16034.5 KFO97401.1 - 0.093 12.7 14.4 0.11 12.4 14.1 1.3 1 1 0 1 1 1 0 JAKMIP CC3 domain DUF4140 PF13600.6 KFO97401.1 - 0.13 12.7 8.4 1.8 9.0 0.2 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) BST2 PF16716.5 KFO97401.1 - 0.29 11.7 15.5 0.28 11.8 5.1 2.5 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 CENP-F_leu_zip PF10473.9 KFO97401.1 - 0.31 11.1 18.5 0.91 9.5 5.3 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc24 PF08286.11 KFO97401.1 - 0.37 11.0 9.1 2.9 8.2 1.5 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF2205 PF10224.9 KFO97401.1 - 0.52 10.3 11.6 0.82 9.7 0.5 2.6 3 0 0 3 3 2 0 Short coiled-coil protein Filament PF00038.21 KFO97401.1 - 0.58 9.7 17.8 0.34 10.5 4.2 2.0 1 1 0 2 2 2 0 Intermediate filament protein FliD_N PF02465.18 KFO97401.1 - 0.59 10.9 2.9 0.5 11.1 0.5 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF1664 PF07889.12 KFO97401.1 - 0.6 10.1 5.4 4.9 7.2 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) OmpH PF03938.14 KFO97401.1 - 0.93 9.8 12.4 0.57 10.5 2.4 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) CENP-H PF05837.12 KFO97401.1 - 1 9.8 13.9 2.7 8.4 3.2 2.3 2 1 0 2 2 2 0 Centromere protein H (CENP-H) Ubiquitin_4 PF18036.1 KFO97401.1 - 2.2 8.4 0.0 2.2 8.4 0.0 2.9 3 0 0 3 3 3 0 Ubiquitin-like domain DUF4047 PF13256.6 KFO97401.1 - 2.5 8.3 9.4 0.35 11.1 1.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) APG6_N PF17675.1 KFO97401.1 - 3.5 8.2 23.2 1.8e+03 -0.6 23.3 2.7 1 1 0 1 1 1 0 Apg6 coiled-coil region Mod_r PF07200.13 KFO97401.1 - 3.7 7.7 17.0 0.83 9.7 4.2 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein RF-1 PF00472.20 KFO97401.1 - 4.3 7.3 10.4 0.65 10.0 3.6 2.1 1 1 1 2 2 2 0 RF-1 domain DUF4094 PF13334.6 KFO97401.1 - 4.5 7.8 7.0 1.1 9.8 1.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) UPF0242 PF06785.11 KFO97401.1 - 4.7 7.3 19.5 1.5e+02 2.3 19.5 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YPEB PF14620.6 KFO97401.1 - 4.8 6.4 9.1 5.1 6.3 3.8 2.0 1 1 1 2 2 2 0 YpeB sporulation TPR_MLP1_2 PF07926.12 KFO97401.1 - 4.9 7.2 17.7 2.5 8.2 3.7 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 KFO97401.1 - 5.2 7.1 17.8 11 6.1 7.4 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 KFO97401.1 - 5.9 7.6 14.6 2.8 8.6 4.1 2.5 1 1 1 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 KFO97401.1 - 6.1 7.4 22.9 2.1 8.8 7.1 2.7 2 1 0 2 2 2 0 Cell division protein ZapB DUF812 PF05667.11 KFO97401.1 - 6.2 5.6 16.1 1.7 7.5 4.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF812) V_ATPase_I PF01496.19 KFO97401.1 - 6.4 4.6 7.7 8.1 4.2 7.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.22 KFO97401.1 - 7.7 6.8 17.9 8.1 6.7 6.4 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Metallophos PF00149.28 KFO97402.1 - 8.6e-15 55.8 0.0 1.3e-14 55.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFO97402.1 - 0.00089 19.5 0.0 0.0072 16.5 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain G-alpha PF00503.20 KFO97403.1 - 1.1e-108 363.6 2.3 1.2e-108 363.4 2.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFO97403.1 - 5.1e-16 58.6 2.4 8.4e-13 48.1 0.4 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFO97403.1 - 7.9e-05 22.3 0.0 0.11 12.0 0.0 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFO97403.1 - 0.00011 21.7 2.3 0.0037 16.7 0.2 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KFO97403.1 - 0.00014 22.1 0.9 0.15 12.3 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KFO97403.1 - 0.0044 16.5 0.2 0.0085 15.5 0.2 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_29 PF13555.6 KFO97403.1 - 0.046 13.5 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KFO97403.1 - 0.15 12.2 0.3 9.5 6.3 0.0 2.8 2 2 0 2 2 2 0 50S ribosome-binding GTPase PBP1_TM PF14812.6 KFO97404.1 - 0.76 10.2 4.4 1.4 9.4 0.2 2.6 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SNAP PF14938.6 KFO97405.1 - 1.9e-27 96.4 13.3 2.6e-27 96.0 13.3 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_MalT PF17874.1 KFO97405.1 - 0.00011 21.7 8.9 0.0048 16.3 7.8 2.2 1 1 1 2 2 2 1 MalT-like TPR region TPR_12 PF13424.6 KFO97405.1 - 0.0023 18.2 17.3 0.018 15.3 3.8 3.8 3 1 0 4 4 4 2 Tetratricopeptide repeat UPF0449 PF15136.6 KFO97405.1 - 0.009 16.5 2.3 1 9.8 0.1 2.7 2 0 0 2 2 2 1 Uncharacterised protein family UPF0449 TPR_8 PF13181.6 KFO97405.1 - 0.05 13.8 9.4 4.7 7.7 0.1 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFO97405.1 - 0.058 14.2 14.4 2.9 8.9 1.6 6.0 2 1 5 7 7 7 0 Tetratricopeptide repeat NSF PF02071.20 KFO97405.1 - 0.081 13.7 14.9 1.3 10.1 0.5 5.9 5 0 0 5 5 5 0 Aromatic-di-Alanine (AdAR) repeat RhoGEF PF00621.20 KFO97405.1 - 0.083 13.1 0.7 0.29 11.3 0.1 2.0 1 1 1 2 2 2 0 RhoGEF domain DUF2150 PF09920.9 KFO97405.1 - 0.27 11.2 2.4 0.43 10.5 0.3 2.2 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) TPR_10 PF13374.6 KFO97405.1 - 0.55 10.2 7.4 1.3 9.0 0.1 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFO97405.1 - 0.6 10.0 13.7 18 5.4 0.1 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFO97405.1 - 2.6 8.4 22.3 4.5 7.6 0.1 7.3 4 2 6 10 10 10 0 Tetratricopeptide repeat APCDDC PF14921.6 KFO97406.1 - 8.8e-130 431.2 6.7 2.4e-104 347.9 1.7 2.4 2 1 0 2 2 2 2 Adenomatosis polyposis coli down-regulated 1 CFC PF09443.10 KFO97406.1 - 4.7 7.1 6.9 2.1 8.2 0.1 2.9 3 0 0 3 3 3 0 Cripto_Frl-1_Cryptic (CFC) Motile_Sperm PF00635.26 KFO97407.1 - 6.2e-31 106.5 0.1 1e-30 105.8 0.1 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 KFO97407.1 - 0.012 15.8 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin GIT_CC PF16559.5 KFO97407.1 - 0.14 12.1 0.2 0.3 11.0 0.2 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Ras PF00071.22 KFO97408.1 - 1.4e-47 161.3 0.0 1.7e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO97408.1 - 1e-26 93.5 0.0 1.7e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO97408.1 - 6.6e-07 28.9 0.0 9e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFO97408.1 - 0.0014 18.6 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Cyt-b5 PF00173.28 KFO97408.1 - 0.051 13.7 0.0 0.29 11.3 0.0 2.0 1 1 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain MMR_HSR1 PF01926.23 KFO97408.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase HEAT PF02985.22 KFO97409.1 - 1.3e-26 90.3 15.3 5.6e-05 23.1 0.3 9.2 8 0 0 8 8 8 6 HEAT repeat HEAT_2 PF13646.6 KFO97409.1 - 1.6e-11 44.4 2.5 0.0058 17.0 0.0 6.4 5 3 3 8 8 8 4 HEAT repeats Cnd1 PF12717.7 KFO97409.1 - 2e-07 31.2 5.9 0.022 14.8 0.4 5.5 6 0 0 6 6 6 3 non-SMC mitotic condensation complex subunit 1 WRNPLPNID PF15017.6 KFO97409.1 - 4.4e-06 27.5 0.4 4.4e-06 27.5 0.4 2.5 2 0 0 2 2 2 1 Putative WW-binding domain and destruction box Vac14_Fab1_bd PF12755.7 KFO97409.1 - 0.16 12.6 7.5 8 7.1 0.1 5.3 4 2 1 5 5 5 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KFO97409.1 - 2.8 8.5 5.5 8.3 7.0 0.0 4.7 6 0 0 6 6 6 0 HEAT-like repeat RhoGAP PF00620.27 KFO97410.1 - 5e-35 120.6 0.4 5e-35 120.6 0.4 3.5 2 2 0 3 3 3 2 RhoGAP domain Tsg PF04668.12 KFO97411.1 - 8.1e-46 156.0 6.6 8.1e-46 156.0 6.6 2.2 2 1 0 2 2 2 1 Twisted gastrulation (Tsg) protein conserved region Ank_2 PF12796.7 KFO97412.1 - 1.8e-18 66.9 0.0 4.2e-12 46.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFO97412.1 - 5.3e-18 64.9 0.1 8.1e-08 32.4 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFO97412.1 - 8e-18 64.0 0.1 0.00032 21.0 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KFO97412.1 - 2.9e-15 54.8 0.0 9.3e-05 22.6 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KFO97412.1 - 1.8e-14 53.9 0.0 3e-07 30.8 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) ISK_Channel PF02060.15 KFO97412.1 - 0.16 11.7 1.2 0.76 9.5 1.2 2.2 1 0 0 1 1 1 0 Slow voltage-gated potassium channel 2Fe-2S_thioredx PF01257.19 KFO97413.1 - 1.2e-66 223.0 0.1 1.4e-66 222.8 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin SOGA PF11365.8 KFO97414.1 - 1e-71 238.1 40.4 1.8e-38 131.5 2.8 5.5 3 1 3 6 6 6 3 Protein SOGA TSC22 PF01166.18 KFO97414.1 - 0.00041 20.6 40.4 0.011 16.0 0.4 6.7 7 1 0 7 7 7 4 TSC-22/dip/bun family DUF948 PF06103.11 KFO97414.1 - 0.0096 16.2 5.2 2.4 8.5 0.0 5.1 6 0 0 6 6 6 1 Bacterial protein of unknown function (DUF948) DUF4201 PF13870.6 KFO97414.1 - 0.91 9.2 0.0 0.91 9.2 0.0 6.8 6 1 2 8 8 8 0 Domain of unknown function (DUF4201) KorB PF08535.10 KFO97414.1 - 1.7 8.7 5.8 22 5.2 0.2 3.3 3 0 0 3 3 3 0 KorB domain Ras PF00071.22 KFO97415.1 - 9.2e-46 155.4 0.3 1.1e-45 155.2 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO97415.1 - 4.2e-22 78.6 0.1 7.1e-22 77.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO97415.1 - 1.1e-11 44.5 0.2 1.4e-11 44.2 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFO97415.1 - 1.7e-05 24.4 0.0 3.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFO97415.1 - 0.003 16.9 0.2 0.0033 16.8 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Y_phosphatase PF00102.27 KFO97416.1 - 1e-150 499.8 0.1 7.2e-84 281.0 0.1 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 KFO97416.1 - 1.4e-25 89.4 13.3 8.2e-11 42.1 0.0 5.7 6 0 0 6 6 5 3 Fibronectin type III domain MAM PF00629.23 KFO97416.1 - 1.3e-22 80.5 0.0 4e-22 78.9 0.0 1.9 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu ig PF00047.25 KFO97416.1 - 3.1e-10 40.1 0.0 8.7e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain DSPc PF00782.20 KFO97416.1 - 1.1e-08 35.0 0.1 0.0031 17.3 0.0 2.6 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFO97416.1 - 4.8e-05 23.4 0.0 0.011 15.8 0.0 2.5 2 0 0 2 2 2 1 Tyrosine phosphatase family Ig_3 PF13927.6 KFO97416.1 - 8.8e-05 23.0 0.0 0.00058 20.4 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFO97416.1 - 0.00013 22.4 1.3 0.23 12.1 0.1 3.9 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain PTPlike_phytase PF14566.6 KFO97416.1 - 0.00015 21.9 0.0 0.083 13.0 0.0 2.7 2 0 0 2 2 2 1 Inositol hexakisphosphate I-set PF07679.16 KFO97416.1 - 0.0011 19.0 0.0 0.0031 17.5 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin I-set domain ECSCR PF15820.5 KFO97416.1 - 0.0064 16.3 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator Ig_2 PF13895.6 KFO97416.1 - 0.011 16.0 0.0 0.072 13.4 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain EphA2_TM PF14575.6 KFO97416.1 - 0.038 14.9 0.3 0.17 12.8 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 KFO97416.1 - 0.043 12.6 0.4 0.093 11.5 0.1 1.6 2 0 0 2 2 2 0 Amnionless DUF948 PF06103.11 KFO97416.1 - 0.1 12.9 0.3 0.35 11.2 0.1 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DctM PF06808.12 KFO97416.1 - 0.11 11.4 0.1 0.16 10.8 0.1 1.1 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporter, DctM component LRR_8 PF13855.6 KFO97417.1 - 3.2e-24 84.5 26.2 1.1e-10 41.1 6.5 4.1 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFO97417.1 - 8.8e-19 67.3 27.6 3.8e-06 27.2 2.9 5.1 2 1 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFO97417.1 - 6.8e-09 35.1 29.5 0.85 10.4 0.3 9.2 9 1 0 9 9 9 4 Leucine Rich Repeat LRR_9 PF14580.6 KFO97417.1 - 9.9e-07 28.4 9.6 0.00055 19.5 1.4 2.3 1 1 1 2 2 2 2 Leucine-rich repeat USP7_C2 PF14533.6 KFO97417.1 - 0.08 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal LRR_6 PF13516.6 KFO97417.1 - 6.7 7.0 32.1 0.48 10.6 0.4 7.3 9 0 0 9 9 9 0 Leucine Rich repeat DUF2371 PF10177.9 KFO97418.1 - 6.8e-63 211.0 0.0 7.9e-63 210.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2371) MFS_1 PF07690.16 KFO97418.1 - 0.0091 14.9 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Neurensin PF14927.6 KFO97418.1 - 0.021 14.5 2.1 0.066 12.9 2.1 2.0 1 1 0 1 1 1 0 Neurensin DUF202 PF02656.15 KFO97418.1 - 0.044 14.2 0.1 14 6.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF2157 PF09925.9 KFO97418.1 - 0.11 12.2 0.0 17 5.2 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF2207 PF09972.9 KFO97418.1 - 0.11 11.2 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM171 PF15471.6 KFO97418.1 - 1.1 8.1 3.2 12 4.8 3.1 2.0 1 1 0 1 1 1 0 Transmembrane protein family 171 AKAP7_NLS PF10469.9 KFO97419.1 - 2.3e-40 138.7 0.3 2.7e-40 138.5 0.3 1.0 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 KFO97419.1 - 9.6e-06 25.6 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KFO97419.1 - 0.028 14.6 0.1 2.9 8.1 0.0 2.6 2 1 0 2 2 2 0 LigT like Phosphoesterase WD40_like PF17005.5 KFO97419.1 - 0.055 12.8 0.1 0.078 12.3 0.1 1.2 1 0 0 1 1 1 0 WD40-like domain 4_1_CTD PF05902.13 KFO97420.1 - 1.8e-51 172.7 14.8 1.8e-51 172.7 14.8 3.3 4 0 0 4 4 4 1 4.1 protein C-terminal domain (CTD) SAB PF04382.13 KFO97420.1 - 1.7e-25 88.8 3.1 6e-25 87.1 3.1 2.1 1 0 0 1 1 1 1 SAB domain FERM_C PF09380.10 KFO97420.1 - 7.2e-24 84.0 0.0 1.8e-23 82.8 0.0 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KFO97420.1 - 8.2e-22 76.9 0.2 5e-21 74.4 0.1 2.3 2 0 0 2 2 2 1 FERM N-terminal domain FERM_M PF00373.18 KFO97420.1 - 5.2e-20 72.0 3.7 3.2e-19 69.5 0.0 3.2 2 1 1 3 3 3 1 FERM central domain FA PF08736.11 KFO97420.1 - 2.2e-18 66.0 4.3 2.2e-18 66.0 4.3 2.2 2 0 0 2 2 2 1 FERM adjacent (FA) RNA_pol_Rpc4 PF05132.14 KFO97420.1 - 0.19 12.1 0.0 0.19 12.1 0.0 5.2 4 2 0 4 4 4 0 RNA polymerase III RPC4 BTB PF00651.31 KFO97421.1 - 2.7e-28 98.4 0.8 5.2e-28 97.5 0.8 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 KFO97421.1 - 1.7e-25 88.0 32.5 2.1e-05 24.7 0.2 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO97421.1 - 2.8e-23 81.2 47.7 9.3e-07 29.0 2.6 6.5 7 0 0 7 7 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFO97421.1 - 2.1e-15 56.1 37.8 0.0043 17.8 1.1 5.8 6 0 0 6 6 5 5 C2H2-type zinc finger zf-met PF12874.7 KFO97421.1 - 2.7e-13 49.8 21.2 0.0051 17.2 0.6 5.6 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFO97421.1 - 2.9e-13 49.7 23.8 0.0063 16.8 0.2 5.8 6 0 0 6 6 5 5 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KFO97421.1 - 0.0083 16.5 36.0 1.1 9.7 5.9 6.5 3 3 2 5 5 5 2 C2HE / C2H2 / C2HC zinc-binding finger zf-MYST PF17772.1 KFO97421.1 - 0.014 14.9 15.2 0.59 9.8 0.2 5.1 3 2 2 5 5 5 0 MYST family zinc finger domain LIM PF00412.22 KFO97421.1 - 0.047 13.9 21.5 0.44 10.8 0.4 4.6 2 2 2 4 4 4 0 LIM domain zf-C2HC_2 PF13913.6 KFO97421.1 - 0.076 12.9 5.6 1.6 8.7 0.1 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type BTB_2 PF02214.22 KFO97421.1 - 0.086 13.2 0.1 0.26 11.6 0.1 1.9 1 0 0 1 1 1 0 BTB/POZ domain zf_UBZ PF18439.1 KFO97421.1 - 0.13 11.8 15.5 1.5 8.5 0.2 5.0 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 KFO97421.1 - 0.15 12.8 14.8 3 8.5 2.6 4.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 KFO97421.1 - 0.19 11.5 9.6 8.8 6.2 0.0 4.5 4 0 0 4 4 4 0 zinc-finger C2H2-type C1_4 PF07975.12 KFO97421.1 - 0.31 11.3 16.0 5.5 7.3 1.7 4.1 1 1 1 3 3 3 0 TFIIH C1-like domain zf-Di19 PF05605.12 KFO97421.1 - 0.68 10.3 23.2 0.42 11.0 3.2 3.3 1 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Yippee-Mis18 PF03226.14 KFO97421.1 - 3.2 8.0 12.4 4.6 7.5 1.7 3.6 4 0 0 4 4 4 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly ADK_lid PF05191.14 KFO97421.1 - 4.2 7.4 6.7 7.4 6.7 2.2 3.0 2 1 1 3 3 3 0 Adenylate kinase, active site lid zf-C2H2_6 PF13912.6 KFO97421.1 - 4.8 7.3 32.0 4.5 7.4 0.4 5.8 5 1 0 5 5 5 0 C2H2-type zinc finger zinc_ribbon_15 PF17032.5 KFO97421.1 - 5.4 7.8 17.6 5.3 7.9 2.0 3.7 2 1 2 4 4 3 0 zinc-ribbon family zf-trcl PF13451.6 KFO97421.1 - 8.4 6.4 16.6 41 4.2 0.1 5.0 4 1 0 4 4 4 0 Probable zinc-ribbon domain Zn-ribbon_8 PF09723.10 KFO97421.1 - 9.5 6.4 19.9 20 5.4 2.2 4.6 2 2 2 4 4 4 0 Zinc ribbon domain AKAP7_RIRII_bdg PF10470.9 KFO97422.1 - 9.4e-07 28.8 3.9 1e-06 28.7 3.9 1.1 1 0 0 1 1 1 1 PKA-RI-RII subunit binding domain of A-kinase anchor protein GKAP PF03359.13 KFO97423.1 - 4.5e-155 516.4 4.4 4.5e-155 516.4 4.4 3.0 3 0 0 3 3 3 2 Guanylate-kinase-associated protein (GKAP) protein Homeobox_KN PF05920.11 KFO97424.1 - 0.00099 19.0 2.3 0.002 18.0 2.3 1.5 1 0 0 1 1 1 1 Homeobox KN domain EF-hand_7 PF13499.6 KFO97425.1 - 9.7e-14 51.6 6.1 1.1e-07 32.2 0.1 2.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KFO97425.1 - 1.2e-13 49.6 12.0 1.3e-07 30.7 1.6 4.5 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 KFO97425.1 - 1.8e-11 43.0 9.4 7.6e-08 31.7 0.9 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 KFO97425.1 - 3.7e-08 33.1 7.1 0.0025 17.6 0.5 3.7 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KFO97425.1 - 1.6e-05 24.2 4.2 1.8e-05 24.0 1.5 2.5 2 0 0 2 2 2 1 EF hand EF-hand_11 PF08976.11 KFO97425.1 - 2.1e-05 25.3 0.2 0.00077 20.3 0.1 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 KFO97425.1 - 0.0021 18.0 0.0 1.5 8.9 0.0 2.9 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0154) EF-hand_9 PF14658.6 KFO97425.1 - 0.0024 18.2 0.0 1.5 9.2 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain GPHH PF16905.5 KFO97425.1 - 0.015 15.0 0.0 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated SurA_N_2 PF13623.6 KFO97425.1 - 0.019 14.8 0.1 2.4 8.0 0.0 2.1 2 0 0 2 2 2 0 SurA N-terminal domain SPARC_Ca_bdg PF10591.9 KFO97425.1 - 0.024 15.0 0.8 0.043 14.1 0.3 1.6 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2267 PF10025.9 KFO97425.1 - 0.04 14.2 0.0 8.6 6.7 0.0 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2267) DUF2666 PF10869.8 KFO97425.1 - 0.095 12.9 0.0 0.43 10.8 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) DDE_Tnp_IS66_C PF13817.6 KFO97425.1 - 0.13 12.5 0.0 3.2 8.1 0.0 2.6 2 0 0 2 2 2 0 IS66 C-terminal element EF-hand_7 PF13499.6 KFO97426.1 - 9.7e-14 51.6 6.1 1.1e-07 32.2 0.1 2.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KFO97426.1 - 1.2e-13 49.6 12.0 1.3e-07 30.7 1.6 4.5 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 KFO97426.1 - 1.8e-11 43.0 9.4 7.6e-08 31.7 0.9 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 KFO97426.1 - 3.7e-08 33.1 7.1 0.0025 17.6 0.5 3.7 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KFO97426.1 - 1.6e-05 24.2 4.2 1.8e-05 24.0 1.5 2.5 2 0 0 2 2 2 1 EF hand EF-hand_11 PF08976.11 KFO97426.1 - 2.1e-05 25.3 0.2 0.00077 20.3 0.1 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 KFO97426.1 - 0.0021 18.0 0.0 1.5 8.9 0.0 2.9 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0154) EF-hand_9 PF14658.6 KFO97426.1 - 0.0024 18.2 0.0 1.5 9.2 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain GPHH PF16905.5 KFO97426.1 - 0.015 15.0 0.0 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated SurA_N_2 PF13623.6 KFO97426.1 - 0.019 14.8 0.1 2.4 8.0 0.0 2.1 2 0 0 2 2 2 0 SurA N-terminal domain SPARC_Ca_bdg PF10591.9 KFO97426.1 - 0.024 15.0 0.8 0.043 14.1 0.3 1.6 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2267 PF10025.9 KFO97426.1 - 0.04 14.2 0.0 8.6 6.7 0.0 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2267) DUF2666 PF10869.8 KFO97426.1 - 0.095 12.9 0.0 0.43 10.8 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) DDE_Tnp_IS66_C PF13817.6 KFO97426.1 - 0.13 12.5 0.0 3.2 8.1 0.0 2.6 2 0 0 2 2 2 0 IS66 C-terminal element fn3 PF00041.21 KFO97427.1 - 8.8e-77 253.5 0.1 3.6e-15 56.1 0.0 5.8 5 0 0 5 5 5 5 Fibronectin type III domain I-set PF07679.16 KFO97427.1 - 4.7e-71 234.9 14.1 2.7e-20 72.2 0.1 7.7 7 0 0 7 7 7 7 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO97427.1 - 9.6e-44 147.9 8.8 1.2e-10 41.8 0.1 7.1 7 0 0 7 7 6 6 Immunoglobulin domain Ig_2 PF13895.6 KFO97427.1 - 6.1e-36 122.6 4.8 6.4e-10 39.2 0.2 6.7 7 0 0 7 7 7 5 Immunoglobulin domain ig PF00047.25 KFO97427.1 - 1.3e-19 70.1 14.9 0.0037 17.4 0.2 7.4 7 0 0 7 7 7 5 Immunoglobulin domain V-set PF07686.17 KFO97427.1 - 9.5e-18 64.4 18.2 0.02 15.1 1.5 9.8 7 3 1 8 8 8 5 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 KFO97427.1 - 1.6e-10 41.4 3.5 0.69 10.5 0.0 7.5 6 1 0 7 7 7 3 Purple acid Phosphatase, N-terminal domain C2-set_2 PF08205.12 KFO97427.1 - 1.1e-07 31.8 2.5 0.0072 16.4 0.0 4.5 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Tissue_fac PF01108.17 KFO97427.1 - 6.9e-06 25.9 0.0 0.34 10.8 0.0 4.1 5 0 0 5 5 5 2 Tissue factor Receptor_2B4 PF11465.8 KFO97427.1 - 0.0016 18.6 0.2 1.3 9.2 0.1 4.7 5 0 0 5 5 5 1 Natural killer cell receptor 2B4 Interfer-bind PF09294.10 KFO97427.1 - 0.068 13.5 0.0 17 5.8 0.0 4.0 4 0 0 4 4 4 0 Interferon-alpha/beta receptor, fibronectin type III Invasin_D3 PF09134.10 KFO97427.1 - 0.31 11.4 3.5 60 4.0 0.1 4.8 5 0 0 5 5 5 0 Invasin, domain 3 BRF1 PF07741.13 KFO97427.1 - 0.88 10.0 5.5 5.3 7.4 0.1 3.0 2 0 0 2 2 2 0 Brf1-like TBP-binding domain LNS2 PF08235.13 KFO97428.1 - 3.7e-103 343.9 0.0 9.5e-103 342.5 0.0 1.7 2 0 0 2 2 2 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KFO97428.1 - 1.2e-44 150.4 0.1 2.3e-44 149.5 0.1 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 KFO97428.1 - 3.4e-34 117.0 0.1 1.1e-33 115.3 0.1 1.9 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain WRNPLPNID PF15017.6 KFO97428.1 - 0.00022 22.1 0.4 0.00022 22.1 0.4 3.3 3 0 0 3 3 3 1 Putative WW-binding domain and destruction box Tash_PEST PF07708.11 KFO97428.1 - 1.2 9.4 5.9 0.24 11.6 1.3 2.4 2 0 0 2 2 2 0 Tash protein PEST motif C1q PF00386.21 KFO97429.1 - 1.4e-15 57.6 0.3 1.1e-14 54.7 0.3 2.0 1 1 0 1 1 1 1 C1q domain OCRE PF17780.1 KFO97429.1 - 0.0071 16.4 0.6 0.013 15.5 0.6 1.4 1 0 0 1 1 1 1 OCRE domain GerPB PF10803.8 KFO97429.1 - 0.16 12.1 0.1 2.6 8.2 0.0 2.5 2 1 0 2 2 2 0 Spore germination GerPB Yae1_N PF09811.9 KFO97430.1 - 3.2e-08 33.1 28.7 1.2 8.9 25.6 3.6 2 1 0 2 2 2 1 Essential protein Yae1, N terminal Sprouty PF05210.13 KFO97431.1 - 4e-28 97.8 36.5 6.8e-28 97.1 36.5 1.4 1 0 0 1 1 1 1 Sprouty protein (Spry) KAR9 PF08580.10 KFO97431.1 - 0.41 9.1 3.9 0.48 8.9 3.9 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 RRM_1 PF00076.22 KFO97432.1 - 2e-11 43.5 0.2 0.0002 21.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 KFO97432.1 - 1.1e-09 38.5 0.3 2.3e-09 37.4 0.3 1.6 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.6 KFO97432.1 - 4.9e-07 29.7 0.0 0.00047 20.1 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 KFO97432.1 - 0.00089 19.1 2.7 0.0017 18.2 2.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFO97432.1 - 0.0054 16.7 1.6 0.01 15.9 1.6 1.5 1 0 0 1 1 1 1 Zinc finger domain RGS-like PF09128.11 KFO97432.1 - 0.053 13.2 0.1 0.053 13.2 0.1 2.6 2 1 0 2 2 2 0 Regulator of G protein signalling-like domain Nup35_RRM PF05172.13 KFO97432.1 - 0.15 12.0 0.1 29 4.7 0.0 2.9 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KFO97432.1 - 0.41 10.7 0.0 0.41 10.7 0.0 3.8 4 1 0 4 4 4 0 RNA binding motif ATP-synt_G PF04718.15 KFO97432.1 - 4.5 8.2 5.1 1.6 9.6 0.4 2.7 1 1 1 2 2 2 0 Mitochondrial ATP synthase g subunit zf-RING_2 PF13639.6 KFO97433.1 - 3.1e-05 24.2 6.0 3.1e-05 24.2 6.0 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFO97433.1 - 3.7e-05 23.5 4.8 0.00019 21.2 4.8 2.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFO97433.1 - 0.00018 21.3 4.6 0.0005 19.9 4.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFO97433.1 - 0.00038 20.7 5.8 0.00038 20.7 5.8 3.1 4 0 0 4 4 3 1 RING-H2 zinc finger domain zf-P11 PF03854.14 KFO97433.1 - 0.00092 18.8 3.6 0.0025 17.5 3.6 1.7 1 0 0 1 1 1 1 P-11 zinc finger zf-C3HC4 PF00097.25 KFO97433.1 - 0.005 16.7 6.2 0.005 16.7 6.2 3.0 4 0 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFO97433.1 - 0.02 14.8 3.7 0.1 12.6 3.7 2.3 1 0 0 1 1 1 0 zinc-RING finger domain DUF1272 PF06906.11 KFO97433.1 - 0.081 13.0 2.4 0.44 10.7 2.4 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Prok-RING_4 PF14447.6 KFO97433.1 - 0.17 11.8 7.7 0.78 9.6 7.7 2.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 TolA_bind_tri PF16331.5 KFO97433.1 - 0.17 11.9 10.5 0.56 10.3 0.7 3.3 2 1 0 2 2 2 0 TolA binding protein trimerisation TSC22 PF01166.18 KFO97433.1 - 0.2 12.0 13.6 0.3 11.4 1.9 4.1 2 1 1 3 3 3 0 TSC-22/dip/bun family zf-RING_UBOX PF13445.6 KFO97433.1 - 0.34 11.0 4.7 0.48 10.5 1.9 2.7 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.6 KFO97433.1 - 0.44 10.4 7.3 0.58 10.0 4.1 3.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DivIC PF04977.15 KFO97433.1 - 0.75 9.6 13.6 1.8 8.4 0.5 3.6 3 0 0 3 3 3 0 Septum formation initiator PRKG1_interact PF15898.5 KFO97433.1 - 0.77 10.7 34.1 0.035 15.0 9.4 4.2 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain CENP-H PF05837.12 KFO97433.1 - 1.4 9.3 27.9 0.78 10.2 7.8 4.0 2 1 1 3 3 3 0 Centromere protein H (CENP-H) ZapB PF06005.12 KFO97433.1 - 1.7 9.2 34.3 1.4 9.4 7.0 4.3 2 1 1 3 3 3 0 Cell division protein ZapB YabA PF06156.13 KFO97433.1 - 7 7.4 24.9 0.36 11.5 3.0 4.2 3 1 1 4 4 4 0 Initiation control protein YabA DHR10 PF18595.1 KFO97433.1 - 8.9 6.4 28.4 10 6.2 3.4 4.7 4 0 0 4 4 4 0 Designed helical repeat protein 10 domain 7tm_1 PF00001.21 KFO97434.1 - 1.4e-39 136.1 10.5 1.7e-39 135.7 10.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFO97434.1 - 5.6e-10 39.0 11.9 1.3e-09 37.9 11.9 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFO97434.1 - 9.7e-08 32.0 5.1 9.7e-08 32.0 5.1 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFO97434.1 - 0.003 17.3 4.4 0.0048 16.7 4.2 1.7 1 1 0 1 1 1 1 Olfactory receptor PHO4 PF01384.20 KFO97434.1 - 0.074 12.1 1.3 0.1 11.6 1.3 1.3 1 0 0 1 1 1 0 Phosphate transporter family Kelch_1 PF01344.25 KFO97435.1 - 9.7e-83 271.6 22.4 2.3e-16 59.1 0.6 6.5 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 KFO97435.1 - 7.8e-38 127.6 2.9 3.2e-05 24.1 0.0 6.4 4 2 2 6 6 6 6 Kelch motif BACK PF07707.15 KFO97435.1 - 7e-37 125.7 1.0 2e-36 124.2 1.0 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 KFO97435.1 - 3.1e-32 111.1 0.8 6.7e-32 110.0 0.8 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.6 KFO97435.1 - 3e-29 100.7 14.0 6.9e-05 23.0 0.2 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 KFO97435.1 - 7.1e-28 95.5 6.0 8e-05 22.5 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 KFO97435.1 - 4.2e-22 77.9 5.1 0.00041 20.3 0.0 6.3 4 1 2 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 KFO97435.1 - 2.1e-05 24.4 10.7 3.3 7.8 0.2 5.3 5 0 0 5 5 5 3 Kelch motif Skp1_POZ PF03931.15 KFO97435.1 - 0.0065 16.6 0.2 0.039 14.1 0.0 2.2 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF3342 PF11822.8 KFO97435.1 - 0.17 12.1 0.9 0.94 9.7 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3342) PQQ_3 PF13570.6 KFO97435.1 - 3.2 8.3 12.7 16 6.1 0.1 4.9 5 0 0 5 5 5 0 PQQ-like domain 7tm_1 PF00001.21 KFO97436.1 - 5.7e-51 173.4 24.6 7.8e-51 172.9 24.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFO97436.1 - 1.4e-05 24.6 23.3 4.1e-05 23.1 23.3 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFO97436.1 - 6.1e-05 22.8 21.3 6.1e-05 22.8 21.3 2.4 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx UQ_con PF00179.26 KFO97436.1 - 0.15 11.7 0.6 0.46 10.1 0.2 1.9 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme I-set PF07679.16 KFO97437.1 - 4.3e-18 65.2 0.0 5.3e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO97437.1 - 3.9e-10 40.2 0.0 5.4e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFO97437.1 - 2.1e-06 27.8 0.0 3.7e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFO97437.1 - 9.8e-06 25.8 0.0 1.8e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFO97437.1 - 0.002 18.3 0.0 0.012 15.8 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_C17orf99 PF17736.1 KFO97437.1 - 0.098 12.7 0.0 0.24 11.5 0.0 1.6 1 1 0 1 1 1 0 C17orf99 Ig domain I-set PF07679.16 KFO97438.1 - 7.4e-40 134.9 0.0 4.1e-20 71.7 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO97438.1 - 8.8e-28 96.7 0.0 8.4e-14 51.9 0.0 3.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFO97438.1 - 4.6e-16 58.9 0.5 2.2e-06 27.9 0.0 3.2 3 1 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFO97438.1 - 8.5e-14 51.5 0.0 1.3e-05 25.3 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 KFO97438.1 - 7.1e-09 35.8 0.0 0.0019 18.3 0.0 3.7 2 1 0 2 2 2 2 Immunoglobulin V-set domain Herpes_gE PF02480.16 KFO97438.1 - 0.0061 15.4 0.0 0.056 12.2 0.0 2.1 1 1 1 2 2 2 1 Alphaherpesvirus glycoprotein E Ig_6 PF18452.1 KFO97438.1 - 0.027 14.0 0.0 0.097 12.3 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin domain RhoGAP PF00620.27 KFO97439.1 - 7.2e-37 126.5 1.8 5.6e-36 123.7 0.0 2.8 3 0 0 3 3 3 1 RhoGAP domain Drc1-Sld2 PF11719.8 KFO97439.1 - 0.0002 21.1 9.5 0.0002 21.1 9.5 3.9 3 2 1 4 4 4 2 DNA replication and checkpoint protein IZUMO PF15005.6 KFO97439.1 - 0.0014 19.1 10.5 0.011 16.2 0.8 3.7 3 1 0 3 3 3 1 Izumo sperm-egg fusion, Ig domain-associated PilJ PF13675.6 KFO97439.1 - 0.19 11.8 4.9 1.3 9.1 1.0 2.6 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Cytochrom_B562 PF07361.11 KFO97439.1 - 5.8 7.6 10.1 0.21 12.3 1.0 2.9 3 1 0 3 3 3 0 Cytochrome b562 Thymosin PF01290.20 KFO97440.1 - 6.3e-21 73.8 10.0 6.8e-21 73.7 10.0 1.0 1 0 0 1 1 1 1 Thymosin beta-4 family WH2 PF02205.20 KFO97440.1 - 0.014 15.2 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 WH2 motif DUF4522 PF15022.6 KFO97440.1 - 0.022 15.0 0.3 0.023 14.9 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4522) wnt PF00110.19 KFO97441.1 - 5.1e-94 315.3 27.2 6.2e-94 315.1 27.2 1.0 1 0 0 1 1 1 1 wnt family NDK PF00334.19 KFO97442.1 - 3.2e-38 130.8 0.0 4.1e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Dpy-30 PF05186.13 KFO97442.1 - 4.5e-18 64.7 0.6 6.8e-18 64.1 0.6 1.3 1 0 0 1 1 1 1 Dpy-30 motif RRM_1 PF00076.22 KFO97443.1 - 4.7e-34 116.0 0.3 1e-15 57.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFO97443.1 - 1.2e-17 63.8 0.5 8.8e-09 35.4 0.1 2.5 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KFO97443.1 - 4.4e-07 29.8 0.0 0.00049 20.0 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KFO97443.1 - 2.8e-05 24.1 0.1 0.1 12.7 0.1 2.4 2 0 0 2 2 2 2 RNA binding motif NID PF07292.13 KFO97443.1 - 0.0062 17.2 0.3 0.56 10.9 0.2 2.4 2 0 0 2 2 2 1 Nmi/IFP 35 domain (NID) Peptidase_M16_C PF05193.21 KFO97443.1 - 0.026 14.6 0.1 0.062 13.3 0.1 1.6 2 0 0 2 2 2 0 Peptidase M16 inactive domain FXMRP1_C_core PF12235.8 KFO97443.1 - 0.34 11.6 5.0 0.73 10.5 5.0 1.6 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal Aminotran_3 PF00202.21 KFO97444.1 - 1.5e-84 284.0 0.0 1.8e-84 283.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KFO97444.1 - 0.00082 18.6 0.1 0.0013 18.0 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Reprolysin PF01421.19 KFO97445.1 - 2.1e-64 217.1 0.1 5.1e-64 215.9 0.1 1.7 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.12 KFO97445.1 - 2.4e-31 108.6 5.3 2.4e-31 108.6 5.3 3.7 3 1 0 3 3 3 1 ADAM cysteine-rich Reprolysin_5 PF13688.6 KFO97445.1 - 4.7e-24 85.6 2.2 1.1e-23 84.4 2.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Disintegrin PF00200.23 KFO97445.1 - 4.2e-19 69.1 26.1 4.2e-19 69.1 26.1 4.5 4 1 0 4 4 4 1 Disintegrin Pep_M12B_propep PF01562.19 KFO97445.1 - 1.3e-17 64.3 0.1 2.5e-17 63.4 0.1 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_3 PF13582.6 KFO97445.1 - 2e-16 60.6 0.2 4e-16 59.6 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFO97445.1 - 1.6e-12 47.8 0.6 3.4e-12 46.7 0.6 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFO97445.1 - 2.9e-10 40.1 0.3 5.3e-10 39.3 0.3 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.13 KFO97445.1 - 0.0025 18.2 13.9 0.0025 18.2 13.9 6.3 6 2 0 6 6 6 1 EGF-like domain Peptidase_M66 PF10462.9 KFO97445.1 - 0.042 12.8 0.4 0.068 12.1 0.4 1.2 1 0 0 1 1 1 0 Peptidase M66 Mg_trans_NIPA PF05653.14 KFO97446.1 - 4e-130 433.2 17.6 4.8e-130 432.9 17.6 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KFO97446.1 - 6.4e-08 32.9 4.2 6.4e-08 32.9 4.2 3.6 3 1 0 3 3 3 1 EamA-like transporter family K1 PF02960.14 KFO97446.1 - 0.15 12.2 9.0 0.062 13.4 2.8 2.8 2 2 0 2 2 2 0 K1 glycoprotein Ctr PF04145.15 KFO97446.1 - 0.45 11.1 0.1 0.45 11.1 0.1 2.3 3 0 0 3 3 3 0 Ctr copper transporter family Pkinase_Tyr PF07714.17 KFO97447.1 - 3.8e-91 305.0 0.0 5.3e-91 304.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO97447.1 - 9.1e-49 166.2 0.0 1.5e-48 165.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFO97447.1 - 5.4e-21 74.5 0.0 1.2e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFO97447.1 - 7.2e-16 57.5 0.3 1.5e-15 56.5 0.3 1.6 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 KFO97447.1 - 2.9e-14 53.4 0.6 1.6e-13 51.1 0.4 2.3 2 0 0 2 2 2 1 PH domain SH3_9 PF14604.6 KFO97447.1 - 5.8e-14 51.7 0.4 1.3e-13 50.6 0.4 1.6 1 0 0 1 1 1 1 Variant SH3 domain BTK PF00779.19 KFO97447.1 - 4.9e-13 48.6 3.6 9.2e-13 47.8 3.6 1.5 1 0 0 1 1 1 1 BTK motif SH3_2 PF07653.17 KFO97447.1 - 1.4e-08 34.3 0.0 2.9e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 KFO97447.1 - 4.2e-05 23.5 0.0 0.00013 22.0 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.11 KFO97447.1 - 4.8e-05 23.5 0.3 0.00013 22.2 0.3 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain PH_8 PF15409.6 KFO97447.1 - 0.00062 20.0 0.2 0.0023 18.2 0.2 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_4 PF06347.13 KFO97447.1 - 0.013 15.3 0.1 0.027 14.3 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Neprosin PF03080.15 KFO97447.1 - 0.051 12.9 0.2 0.12 11.7 0.2 1.6 1 0 0 1 1 1 0 Neprosin Kinase-like PF14531.6 KFO97447.1 - 0.12 11.7 0.0 0.52 9.6 0.0 1.8 2 0 0 2 2 2 0 Kinase-like RFC1 PF08519.12 KFO97447.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain Med7 PF05983.11 KFO97448.1 - 3.7e-46 157.6 7.7 3.1e-45 154.6 7.7 2.0 1 1 0 1 1 1 1 MED7 protein DotU PF09850.9 KFO97448.1 - 0.11 12.2 2.0 9.1 5.9 0.5 2.2 2 0 0 2 2 2 0 Type VI secretion system protein DotU V-set PF07686.17 KFO97449.1 - 1.9e-14 53.8 2.5 5.2e-14 52.3 0.9 2.1 1 1 1 2 2 2 1 Immunoglobulin V-set domain ig PF00047.25 KFO97449.1 - 9.1e-05 22.6 1.6 0.00044 20.4 0.3 2.5 1 1 1 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFO97449.1 - 0.00013 22.0 0.1 0.00035 20.6 0.1 1.8 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFO97449.1 - 0.00061 20.1 4.6 0.002 18.4 1.9 2.7 1 1 1 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 KFO97449.1 - 0.0045 17.6 5.1 0.0058 17.2 0.5 3.0 2 2 0 2 2 2 1 Immunoglobulin domain DUF3309 PF11752.8 KFO97449.1 - 0.014 15.4 0.3 0.025 14.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) Receptor_2B4 PF11465.8 KFO97449.1 - 0.022 14.9 0.3 0.11 12.7 0.0 2.2 2 1 1 3 3 3 0 Natural killer cell receptor 2B4 MIF4G PF02854.19 KFO97450.1 - 2.6e-28 99.1 6.5 3.9e-28 98.6 6.5 1.3 1 0 0 1 1 1 1 MIF4G domain Sec34 PF04136.15 KFO97450.1 - 0.026 14.4 2.9 0.053 13.4 2.9 1.6 1 0 0 1 1 1 0 Sec34-like family Goodbye PF17109.5 KFO97450.1 - 0.66 10.4 2.6 1.4 9.4 0.3 2.4 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain Cauli_AT PF03233.13 KFO97450.1 - 7.4 6.5 10.8 0.15 12.0 3.5 1.8 2 0 0 2 2 2 0 Aphid transmission protein MH2 PF03166.14 KFO97451.1 - 1.4e-50 172.1 0.4 1.6e-50 171.9 0.4 1.0 1 0 0 1 1 1 1 MH2 domain Dymeclin PF09742.9 KFO97452.1 - 4.1e-10 38.7 0.8 4.3e-10 38.7 0.8 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein TUTF7_u4 PF16631.5 KFO97454.1 - 2.6e-38 130.5 21.8 2.6e-38 130.5 21.8 3.5 4 0 0 4 4 4 1 Unstructured region 4 on terminal uridylyltransferase 7 PAP_assoc PF03828.19 KFO97454.1 - 3.9e-27 94.2 0.1 2.2e-14 53.4 0.2 3.1 2 0 0 2 2 2 2 Cid1 family poly A polymerase zf-CCHC PF00098.23 KFO97454.1 - 3e-14 52.3 19.5 3.3e-05 23.7 2.3 3.6 3 0 0 3 3 3 3 Zinc knuckle NTP_transf_2 PF01909.23 KFO97454.1 - 5.8e-07 29.7 0.0 3.6e-05 24.0 0.0 3.1 2 0 0 2 2 2 1 Nucleotidyltransferase domain zf-CCHC_2 PF13696.6 KFO97454.1 - 4e-06 26.5 27.6 0.011 15.5 5.7 4.5 4 0 0 4 4 4 3 Zinc knuckle tRNA_NucTransf2 PF09249.11 KFO97454.1 - 0.00047 20.4 0.0 2 8.7 0.0 2.9 2 0 0 2 2 2 2 tRNA nucleotidyltransferase, second domain zf-CCHC_4 PF14392.6 KFO97454.1 - 0.00096 18.8 13.3 0.23 11.2 0.3 3.6 3 0 0 3 3 3 2 Zinc knuckle Polbeta PF18765.1 KFO97454.1 - 0.0025 17.9 0.1 0.17 12.0 0.0 2.8 2 1 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase zf-C2H2_jaz PF12171.8 KFO97454.1 - 0.033 14.5 3.2 0.14 12.5 3.2 2.2 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFO97454.1 - 0.13 12.6 4.7 0.068 13.5 0.8 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Fe-S_biosyn PF01521.20 KFO97455.1 - 8.4e-19 67.8 0.0 9.3e-19 67.7 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Sad1_UNC PF07738.13 KFO97456.1 - 3e-32 111.4 0.0 3.3e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Pepdidase_M14_N PF18027.1 KFO97458.1 - 6.9e-16 58.6 2.7 1.8e-15 57.2 2.7 1.8 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 KFO97458.1 - 1.5e-12 48.0 0.0 3.6e-12 46.7 0.0 1.7 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 KFO97458.1 - 0.0063 15.6 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family V-ATPase_H_N PF03224.14 KFO97458.1 - 0.011 15.0 3.3 0.015 14.6 0.1 2.6 3 1 0 3 3 3 0 V-ATPase subunit H Sad1_UNC PF07738.13 KFO97459.1 - 3.6e-30 104.7 0.0 4e-30 104.5 0.0 1.0 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal SNF2_N PF00176.23 KFO97460.1 - 1.6e-66 224.5 0.7 3e-66 223.5 0.7 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain CDH1_2_SANT_HL1 PF18375.1 KFO97460.1 - 2e-32 111.7 0.0 2e-32 111.7 0.0 4.3 4 0 0 4 4 4 1 CDH1/2 SANT-Helical linker 1 Chromo PF00385.24 KFO97460.1 - 1.8e-29 101.4 11.4 1.4e-19 69.7 0.1 4.0 4 0 0 4 4 4 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 KFO97460.1 - 3.2e-27 94.8 2.4 3.2e-27 94.8 2.4 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 KFO97460.1 - 2.5e-20 72.9 0.0 7.2e-20 71.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CHDCT2 PF08074.11 KFO97460.1 - 0.0067 16.6 1.2 0.021 15.0 0.0 2.5 2 0 0 2 2 2 1 CHDCT2 (NUC038) domain RVT_1 PF00078.27 KFO97461.1 - 2.4e-16 59.9 0.0 3.6e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TetR_C_4 PF08359.11 KFO97462.1 - 0.025 14.7 0.0 0.025 14.7 0.0 1.1 1 0 0 1 1 1 0 YsiA-like protein, C-terminal region DUF3947 PF13135.6 KFO97462.1 - 0.034 14.3 0.3 0.035 14.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) Dynamin_N PF00350.23 KFO97464.1 - 2.9e-16 60.0 0.1 2.9e-16 60.0 0.1 2.6 2 2 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KFO97464.1 - 2.3e-06 27.6 0.4 6e-05 23.1 0.4 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KFO97464.1 - 0.0042 17.6 3.3 0.0045 17.5 0.0 2.4 2 1 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 KFO97464.1 - 0.0047 16.8 1.2 0.036 14.0 0.0 2.9 2 1 1 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 KFO97464.1 - 0.0051 16.4 2.2 3.9 7.0 0.0 2.8 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_21 PF13304.6 KFO97464.1 - 0.0076 16.1 0.1 0.049 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KFO97464.1 - 0.022 14.8 0.2 0.022 14.8 0.2 2.6 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_23 PF13476.6 KFO97464.1 - 0.026 15.0 14.6 0.054 14.0 0.1 3.0 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 KFO97464.1 - 0.045 13.5 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 KFO97464.1 - 0.048 13.3 0.5 0.28 10.8 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 KFO97464.1 - 0.056 13.2 0.2 0.39 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 KFO97464.1 - 0.059 12.7 3.4 0.27 10.5 0.3 2.8 2 1 0 2 2 2 0 AIG1 family AAA_18 PF13238.6 KFO97464.1 - 0.17 12.5 2.4 5.1 7.7 0.0 3.3 2 1 1 3 3 3 0 AAA domain Abhydrolase_1 PF00561.20 KFO97466.1 - 3e-35 122.1 0.0 6.2e-34 117.8 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFO97466.1 - 3.1e-14 54.1 9.0 3.1e-14 54.1 9.0 2.5 2 2 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFO97466.1 - 1.4e-13 50.7 0.0 4e-11 42.6 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ndr PF03096.14 KFO97466.1 - 0.1 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Ndr family Neur_chan_memb PF02932.16 KFO97467.1 - 5.8e-88 295.0 17.2 8.2e-63 212.6 13.8 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFO97467.1 - 4.7e-78 261.5 4.2 6e-78 261.2 4.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Glycoprotein PF03409.15 KFO97467.1 - 0.069 12.0 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Transmembrane glycoprotein DUF2417 PF10329.9 KFO97467.1 - 1 8.7 12.3 2.6 7.4 12.2 1.7 1 1 0 1 1 1 0 Region of unknown function (DUF2417) Pkinase_Tyr PF07714.17 KFO97468.1 - 4.1e-91 304.8 0.0 7.7e-91 303.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO97468.1 - 1.5e-41 142.5 0.0 2.6e-41 141.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Focal_AT PF03623.13 KFO97468.1 - 3.1e-40 137.2 0.0 6e-40 136.3 0.0 1.5 1 0 0 1 1 1 1 Focal adhesion targeting region FERM_M PF00373.18 KFO97468.1 - 2.1e-10 41.0 3.5 2.1e-10 41.0 3.5 2.0 2 0 0 2 2 2 1 FERM central domain FERM_N_2 PF18038.1 KFO97468.1 - 9.6e-08 32.8 0.1 5.3e-05 24.0 0.1 2.8 2 0 0 2 2 2 2 FERM N-terminal domain Haspin_kinase PF12330.8 KFO97468.1 - 0.044 12.7 0.0 0.085 11.8 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain HEAT PF02985.22 KFO97469.1 - 1.7e-18 65.1 4.7 4.1e-05 23.5 0.0 8.9 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.6 KFO97469.1 - 1.4e-15 57.4 1.3 2.3e-10 40.7 0.0 6.4 7 1 1 8 8 8 1 HEAT-like repeat IBN_N PF03810.19 KFO97469.1 - 1.5e-10 40.8 0.6 1.8e-09 37.4 0.0 3.0 2 1 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KFO97469.1 - 9.8e-09 35.5 0.2 0.00037 20.8 0.0 5.2 2 2 3 5 5 5 3 HEAT repeats Arm PF00514.23 KFO97469.1 - 1.5e-07 31.2 6.4 0.0031 17.5 0.0 5.0 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KFO97469.1 - 3.9e-05 23.3 3.0 0.49 9.9 0.0 4.4 3 1 1 4 4 4 2 CLASP N terminal Cnd1 PF12717.7 KFO97469.1 - 5.9e-05 23.2 5.1 0.016 15.2 0.0 3.7 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 KFO97469.1 - 0.84 9.8 8.1 0.6 10.2 0.3 3.4 4 0 0 4 4 4 0 V-ATPase subunit H Peptidase_M1 PF01433.20 KFO97470.1 - 1.3e-92 309.3 0.4 2e-92 308.7 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KFO97470.1 - 6.2e-88 295.4 0.0 3.9e-87 292.8 0.0 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KFO97470.1 - 5.1e-50 170.2 0.1 9.6e-50 169.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Tim44 PF04280.15 KFO97471.1 - 4.4e-31 108.0 0.0 5.6e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Tim44-like domain ChaB PF06150.12 KFO97471.1 - 0.013 16.0 2.3 0.015 15.8 0.0 2.3 3 0 0 3 3 3 0 ChaB MBA1 PF07961.11 KFO97471.1 - 0.056 12.5 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 MBA1-like protein 7tm_3 PF00003.22 KFO97472.1 - 1.4e-27 97.0 6.5 2.3e-27 96.3 6.5 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Ribosomal_L29 PF00831.23 KFO97472.1 - 0.13 12.2 0.9 0.26 11.3 0.9 1.4 1 0 0 1 1 1 0 Ribosomal L29 protein Abhydrolase_9_N PF15420.6 KFO97472.1 - 1.7 8.6 6.4 7.6 6.5 6.4 1.9 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus RhoGAP PF00620.27 KFO97473.1 - 3.8e-24 85.2 0.0 4e-24 85.2 0.0 1.0 1 0 0 1 1 1 1 RhoGAP domain RAWUL PF16207.5 KFO97474.1 - 8e-21 74.5 0.8 1.2e-20 73.9 0.8 1.3 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like Rad60-SLD PF11976.8 KFO97474.1 - 0.048 13.5 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Proteasome PF00227.26 KFO97475.1 - 4.7e-33 114.3 0.0 5.2e-33 114.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit PIP5K PF01504.18 KFO97476.1 - 1.2e-76 257.6 0.1 1.7e-76 257.1 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase CWC25 PF12542.8 KFO97477.1 - 9.2e-22 77.9 0.1 9.2e-22 77.9 0.1 4.1 4 1 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 KFO97477.1 - 1.5e-15 57.0 13.8 1.5e-15 57.0 13.8 5.8 5 1 1 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR tRNA-synt_1c PF00749.21 KFO97477.1 - 0.0017 17.3 3.7 0.0017 17.3 3.7 3.0 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), catalytic domain Ribosomal_L14 PF00238.19 KFO97478.1 - 4e-36 123.8 0.2 4.7e-36 123.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SH3_9 PF14604.6 KFO97479.1 - 2.4e-15 56.1 0.2 3.8e-15 55.5 0.2 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFO97479.1 - 5.2e-13 48.4 0.1 8.6e-13 47.7 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFO97479.1 - 1.1e-07 31.4 0.0 3e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain LIM PF00412.22 KFO97479.1 - 3.4e-07 30.4 7.4 5.5e-07 29.7 7.4 1.3 1 0 0 1 1 1 1 LIM domain Nebulin PF00880.18 KFO97479.1 - 3.4e-05 23.6 0.5 0.053 13.4 0.2 2.7 2 0 0 2 2 2 2 Nebulin repeat Cadherin_C_2 PF16492.5 KFO97479.1 - 0.33 11.7 1.3 0.6 10.9 0.5 1.8 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Ribosomal_L19e PF01280.20 KFO97481.1 - 1e-65 220.2 12.9 1e-65 220.2 12.9 2.0 1 1 1 2 2 2 1 Ribosomal protein L19e DUF1682 PF07946.14 KFO97481.1 - 4.6 6.4 15.4 5.8 6.0 15.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) LRR_4 PF12799.7 KFO97482.1 - 2e-20 72.5 12.1 0.0066 16.8 0.4 6.4 6 0 0 6 6 6 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFO97482.1 - 5.9e-19 66.5 26.6 0.0028 17.6 0.1 10.6 12 0 0 12 12 12 6 Leucine Rich repeat LRR_8 PF13855.6 KFO97482.1 - 1.3e-06 28.1 4.5 0.023 14.4 0.7 5.2 4 2 1 5 5 5 2 Leucine rich repeat LRR_1 PF00560.33 KFO97482.1 - 1.2e-05 25.2 24.7 7.6 7.5 0.2 9.8 10 2 0 10 10 10 3 Leucine Rich Repeat Med1 PF10744.9 KFO97483.1 - 1.1e-63 215.8 0.0 6.7e-63 213.2 0.0 2.4 2 0 0 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 Pkinase PF00069.25 KFO97484.1 - 1e-73 247.9 0.1 2.3e-73 246.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO97484.1 - 1.5e-33 116.2 0.0 2.7e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFO97484.1 - 2.4e-07 30.0 0.2 2.4e-07 30.0 0.2 2.4 3 0 0 3 3 3 1 Haspin like kinase domain Kinase-like PF14531.6 KFO97484.1 - 0.00024 20.5 0.0 0.0022 17.4 0.0 2.1 1 1 0 1 1 1 1 Kinase-like HLH PF00010.26 KFO97485.1 - 5.1e-17 61.6 1.6 5.1e-17 61.6 1.6 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain MENTAL PF10457.9 KFO97486.1 - 3.6e-63 212.6 8.4 4.1e-63 212.4 8.4 1.0 1 0 0 1 1 1 1 Cholesterol-capturing domain DUF2070 PF09843.9 KFO97486.1 - 4.9 5.3 9.4 5.9 5.1 9.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Per1 PF04080.13 KFO97487.1 - 1.9e-45 155.6 10.3 1.9e-24 86.8 0.4 2.0 2 0 0 2 2 2 2 Per1-like family Pkinase_Tyr PF07714.17 KFO97488.1 - 1.2e-87 293.5 0.0 2.1e-87 292.7 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Recep_L_domain PF01030.24 KFO97488.1 - 2.7e-48 162.8 0.0 4.2e-29 100.9 0.0 2.7 2 1 0 2 2 2 2 Receptor L domain Pkinase PF00069.25 KFO97488.1 - 1.7e-37 129.2 0.0 2.9e-37 128.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain GF_recep_IV PF14843.6 KFO97488.1 - 4.8e-27 94.3 64.4 3.6e-25 88.3 15.2 4.2 2 1 1 3 3 3 2 Growth factor receptor domain IV Furin-like PF00757.20 KFO97488.1 - 8.1e-27 93.9 71.3 5.8e-26 91.2 39.6 3.2 2 1 0 2 2 2 1 Furin-like cysteine rich region Haspin_kinase PF12330.8 KFO97488.1 - 0.002 17.1 0.1 0.0043 16.1 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Protocadherin PF08374.11 KFO97488.1 - 0.0041 17.1 0.0 0.0069 16.4 0.0 1.2 1 0 0 1 1 1 1 Protocadherin EphA2_TM PF14575.6 KFO97488.1 - 0.008 17.0 0.1 0.019 15.8 0.1 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain APH PF01636.23 KFO97488.1 - 0.011 15.7 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Adeno_E3_CR2 PF02439.15 KFO97488.1 - 0.018 14.8 0.1 0.035 13.9 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Rdx PF10262.9 KFO97489.1 - 6.9e-14 51.8 0.0 8e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Rdx family SH2 PF00017.24 KFO97490.1 - 1.5e-15 57.1 0.0 2.9e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 SH2 domain RA PF00788.23 KFO97490.1 - 1.2e-14 54.7 0.0 3.3e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain PH PF00169.29 KFO97490.1 - 2.3e-08 34.5 0.1 1e-07 32.4 0.1 1.9 2 0 0 2 2 2 1 PH domain PelD_GGDEF PF16963.5 KFO97490.1 - 0.055 13.3 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 PelD GGDEF domain adh_short PF00106.25 KFO97491.1 - 2.2e-41 141.4 0.0 2.8e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFO97491.1 - 6.6e-26 91.3 0.0 9.7e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFO97491.1 - 6e-10 39.3 0.2 8.1e-10 38.9 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFO97491.1 - 0.025 14.0 0.0 0.19 11.2 0.0 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family zf-H2C2_2 PF13465.6 KFO97492.1 - 1.8e-23 81.8 33.1 4.4e-07 30.0 3.8 5.8 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFO97492.1 - 1.9e-16 59.5 38.6 7.2e-06 26.2 0.4 6.6 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO97492.1 - 5.6e-12 45.4 39.4 0.00018 22.0 0.3 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFO97492.1 - 0.00049 19.8 32.4 0.0026 17.5 0.1 5.4 5 0 0 5 5 5 3 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KFO97492.1 - 0.0041 16.9 0.2 0.0041 16.9 0.2 4.8 6 1 0 6 6 5 1 zinc-finger C2H2-type zf-MYND PF01753.18 KFO97492.1 - 0.037 14.1 0.2 0.037 14.1 0.2 3.9 3 1 1 4 4 4 0 MYND finger GAGA PF09237.11 KFO97492.1 - 0.068 13.0 2.6 0.096 12.5 0.1 2.4 1 1 0 2 2 2 0 GAGA factor zf-C2H2_6 PF13912.6 KFO97492.1 - 0.076 13.0 40.8 0.34 11.0 0.2 6.6 6 0 0 6 6 6 0 C2H2-type zinc finger DUF3268 PF11672.8 KFO97492.1 - 0.19 12.0 0.3 0.19 12.0 0.3 3.1 3 1 0 3 3 3 0 zinc-finger-containing domain zf-C2HE PF16278.5 KFO97492.1 - 0.5 10.9 19.2 0.53 10.8 0.8 4.4 2 1 2 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-RING_7 PF02591.15 KFO97492.1 - 3.8 7.8 9.4 29 4.9 0.1 3.8 4 0 0 4 4 3 0 C4-type zinc ribbon domain AKAP95 PF04988.12 KFO97492.1 - 8.1 6.6 8.2 3.6 7.8 0.4 2.5 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Sp38 PF07354.12 KFO97493.1 - 1.6e-79 265.4 10.2 2.2e-79 265.0 10.2 1.2 1 0 0 1 1 1 1 Zona-pellucida-binding protein (Sp38) HypA PF01155.19 KFO97493.1 - 0.77 9.8 5.0 0.47 10.5 2.8 1.8 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA LRR_8 PF13855.6 KFO97494.1 - 1.2e-17 63.4 5.1 2e-11 43.5 0.1 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFO97494.1 - 1.1e-07 32.1 5.0 0.045 14.2 1.8 3.5 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) DUF3700 PF12481.8 KFO97494.1 - 0.00051 19.5 0.1 0.002 17.6 0.0 1.9 2 1 0 2 2 2 1 Aluminium induced protein LRR_5 PF13306.6 KFO97494.1 - 0.0046 16.9 0.0 0.008 16.1 0.0 1.4 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRRNT PF01462.18 KFO97494.1 - 0.0058 16.2 0.5 0.017 14.8 0.1 2.1 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KFO97494.1 - 0.012 16.1 14.7 0.27 11.9 0.6 4.9 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 KFO97494.1 - 0.037 14.1 6.3 2.4 8.5 0.2 3.3 3 0 0 3 3 3 0 Leucine Rich repeat Phtf-FEM1B_bdg PF12129.8 KFO97494.1 - 0.081 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor Coiled PF05710.12 KFO97494.1 - 0.16 12.8 1.1 0.39 11.6 0.3 1.9 1 1 1 2 2 2 0 Coiled coil ORMDL PF04061.14 KFO97495.1 - 1.9e-54 183.2 4.8 2.1e-54 183.0 4.8 1.0 1 0 0 1 1 1 1 ORMDL family Hormone_recep PF00104.30 KFO97496.1 - 3.3e-15 56.2 0.0 5.2e-15 55.6 0.0 1.3 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Btz PF09405.10 KFO97497.1 - 1.6e-23 83.4 6.9 1.6e-23 83.4 6.9 2.6 2 1 1 3 3 3 1 CASC3/Barentsz eIF4AIII binding Cdc6_C PF09079.11 KFO97498.1 - 3.1e-18 65.5 1.4 5.9e-18 64.6 1.4 1.5 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_22 PF13401.6 KFO97498.1 - 2.7e-12 47.1 0.0 6.8e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFO97498.1 - 2.2e-09 37.9 4.3 1.1e-07 32.4 0.4 3.0 3 1 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 KFO97498.1 - 7e-09 36.2 0.0 1.2e-08 35.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 KFO97498.1 - 1.1e-07 31.9 0.5 7.7e-07 29.2 0.1 2.1 2 0 0 2 2 2 1 AAA lid domain NACHT PF05729.12 KFO97498.1 - 2.8e-05 24.1 0.1 6.3e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 NACHT domain DUF2277 PF10041.9 KFO97498.1 - 0.0032 17.8 0.2 0.01 16.1 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2277) DUF2075 PF09848.9 KFO97498.1 - 0.0092 15.3 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KFO97498.1 - 0.013 15.2 0.0 0.47 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain HTH_22 PF13309.6 KFO97498.1 - 0.098 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 HTH domain AAA_19 PF13245.6 KFO97498.1 - 0.1 12.9 0.0 0.39 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Hormone_recep PF00104.30 KFO97499.1 - 9.7e-13 48.2 0.1 1.8e-12 47.3 0.1 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DNA_topoisoIV PF00521.20 KFO97500.1 - 5.6e-134 447.2 0.7 1.1e-133 446.3 0.0 1.8 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KFO97500.1 - 9e-49 165.0 6.4 9e-49 165.0 6.4 2.8 4 0 0 4 4 4 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KFO97500.1 - 9.3e-29 100.1 1.2 2.3e-28 98.9 1.2 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KFO97500.1 - 6.6e-16 58.8 0.0 2e-15 57.2 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KFO97500.1 - 1.2e-09 38.2 0.0 3.7e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Thyroglobulin_1 PF00086.18 KFO97501.1 - 4.4e-20 71.1 0.7 4.4e-20 71.1 0.7 1.6 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat PTB PF08416.13 KFO97502.1 - 6.1e-25 87.9 0.0 1.1e-24 87.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH2 PF00017.24 KFO97502.1 - 7.8e-11 41.9 0.0 1.5e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 SH2 domain HMG_box PF00505.19 KFO97503.1 - 3e-18 66.0 1.7 3e-18 66.0 1.7 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFO97503.1 - 4.4e-06 27.2 0.6 4.4e-06 27.2 0.6 2.5 2 0 0 2 2 2 1 HMG-box domain Pepsin-I3 PF06394.13 KFO97503.1 - 0.24 11.6 1.9 0.3 11.3 0.2 2.1 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain Filament PF00038.21 KFO97504.1 - 5.2e-27 95.3 24.8 7.5e-27 94.7 24.8 1.2 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.12 KFO97504.1 - 0.02 15.0 6.0 0.02 15.0 6.0 2.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 KFO97504.1 - 0.034 14.2 5.0 0.042 13.9 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Phospholip_B PF04916.13 KFO97504.1 - 0.13 10.9 0.2 0.21 10.1 0.2 1.4 1 0 0 1 1 1 0 Phospholipase B Tox-REase-5 PF15648.6 KFO97504.1 - 0.14 12.7 1.2 0.84 10.2 0.2 2.4 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 5 FUSC PF04632.12 KFO97504.1 - 0.15 10.6 9.2 0.19 10.2 9.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family U3_assoc_6 PF08640.11 KFO97504.1 - 0.22 11.6 7.6 0.22 11.6 1.1 2.8 1 1 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 DUF3736 PF12540.8 KFO97504.1 - 0.24 11.5 4.1 0.43 10.7 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3736) UPF0242 PF06785.11 KFO97504.1 - 1.3 9.1 19.5 0.73 9.9 16.4 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus EST1 PF10374.9 KFO97504.1 - 1.4 9.6 6.7 0.74 10.5 2.1 2.3 1 1 1 2 2 2 0 Telomerase activating protein Est1 BST2 PF16716.5 KFO97504.1 - 1.9 9.1 17.2 0.095 13.3 3.1 3.8 1 1 4 5 5 5 0 Bone marrow stromal antigen 2 V_ATPase_I PF01496.19 KFO97504.1 - 5.1 4.9 10.1 6.3 4.6 10.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family V-SNARE PF05008.15 KFO97504.1 - 8.5 6.8 13.8 2.4 8.6 5.9 2.9 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Filament PF00038.21 KFO97505.1 - 2.7e-99 332.7 20.9 1.3e-72 245.1 3.8 2.0 1 1 1 2 2 2 2 Intermediate filament protein DUF4407 PF14362.6 KFO97505.1 - 0.00063 19.2 8.7 1.5 8.2 2.2 3.1 1 1 2 3 3 3 3 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 KFO97505.1 - 0.0025 17.9 1.4 0.0025 17.9 1.4 3.8 3 1 1 4 4 4 1 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 KFO97505.1 - 0.025 15.1 23.8 0.09 13.3 1.5 3.4 3 0 0 3 3 3 0 Apg6 coiled-coil region Atg14 PF10186.9 KFO97505.1 - 0.16 11.1 9.4 0.069 12.2 2.7 2.7 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prefoldin_2 PF01920.20 KFO97505.1 - 0.22 11.5 17.6 0.79 9.7 0.0 4.2 3 2 1 4 4 4 0 Prefoldin subunit Noelin-1 PF12308.8 KFO97505.1 - 0.28 11.2 6.6 4 7.5 1.1 3.3 3 1 0 3 3 3 0 Neurogenesis glycoprotein DivIC PF04977.15 KFO97505.1 - 0.51 10.2 25.1 1.8 8.4 2.1 4.9 5 0 0 5 5 5 0 Septum formation initiator SlyX PF04102.12 KFO97505.1 - 0.69 10.6 17.5 6.5 7.5 0.7 3.9 4 0 0 4 4 3 0 SlyX RasGAP_C PF03836.15 KFO97505.1 - 0.98 9.6 12.8 0.38 10.9 1.1 3.1 1 1 2 3 3 3 0 RasGAP C-terminus FlxA PF14282.6 KFO97505.1 - 1.3 9.1 16.2 3.5 7.7 0.1 2.9 3 1 0 3 3 3 0 FlxA-like protein CHDCT2 PF08074.11 KFO97505.1 - 1.9 8.6 6.4 1.1 9.4 1.7 2.3 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain TolA_bind_tri PF16331.5 KFO97505.1 - 2 8.6 25.8 1.6 8.9 8.9 4.1 3 2 0 4 4 4 0 TolA binding protein trimerisation Jnk-SapK_ap_N PF09744.9 KFO97505.1 - 2.2 8.5 21.7 0.12 12.6 2.4 3.2 2 1 0 3 3 3 0 JNK_SAPK-associated protein-1 DUF4140 PF13600.6 KFO97505.1 - 2.3 8.7 11.2 3.4 8.2 0.6 3.6 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Phage_GP20 PF06810.11 KFO97505.1 - 2.6 7.9 14.7 1.4 8.7 0.8 3.7 2 1 1 3 3 3 0 Phage minor structural protein GP20 XhlA PF10779.9 KFO97505.1 - 2.8 8.2 8.1 2.4 8.5 0.8 3.0 3 0 0 3 3 2 0 Haemolysin XhlA Lzipper-MIP1 PF14389.6 KFO97505.1 - 3.1 8.2 13.5 0.31 11.4 1.4 3.4 3 1 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF4446 PF14584.6 KFO97505.1 - 4.1 7.4 7.9 1.5 8.8 0.0 3.2 3 1 2 5 5 5 0 Protein of unknown function (DUF4446) DUF724 PF05266.14 KFO97505.1 - 5.8 6.7 15.9 9.7 6.0 5.4 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF724) Filament PF00038.21 KFO97506.1 - 3.9e-99 332.2 39.2 4.4e-99 332.0 39.2 1.0 1 0 0 1 1 1 1 Intermediate filament protein DUF573 PF04504.14 KFO97506.1 - 0.019 15.6 0.6 0.019 15.6 0.6 2.9 2 1 1 3 3 3 0 Protein of unknown function, DUF573 Prefoldin_2 PF01920.20 KFO97506.1 - 0.071 13.1 0.3 0.071 13.1 0.3 5.2 3 2 0 4 4 4 0 Prefoldin subunit SRP1_TIP1 PF00660.17 KFO97506.1 - 0.36 10.9 3.0 1.1 9.4 0.1 2.6 2 1 0 2 2 2 0 Seripauperin and TIP1 family RNase_HII PF01351.18 KFO97506.1 - 0.39 10.5 4.4 1.1 9.1 4.4 1.7 1 0 0 1 1 1 0 Ribonuclease HII Terminase_6C PF17289.2 KFO97506.1 - 1.4 9.0 5.2 0.54 10.3 0.2 2.2 1 1 0 2 2 2 0 Terminase RNaseH-like domain Clr5 PF14420.6 KFO97506.1 - 1.7 8.9 6.3 2.6 8.4 0.1 3.1 3 0 0 3 3 3 0 Clr5 domain DUF1664 PF07889.12 KFO97506.1 - 3.9 7.5 21.6 4.4 7.4 0.2 3.8 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.9 KFO97506.1 - 4.6 7.4 40.4 0.19 11.9 3.2 4.1 2 2 2 4 4 4 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 KFO97506.1 - 6.7 7.2 43.7 3.2 8.3 5.9 3.9 2 2 0 3 3 3 0 Apg6 coiled-coil region Spc7 PF08317.11 KFO97506.1 - 7 5.4 35.4 0.52 9.1 9.1 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4854 PF16146.5 KFO97506.1 - 7.2 7.0 16.1 11 6.4 0.1 4.4 3 2 2 5 5 5 0 Domain of unknown function (DUF4854) PRP1_N PF06424.12 KFO97506.1 - 7.8 6.9 11.9 1.4 9.3 8.0 1.8 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Filament PF00038.21 KFO97507.1 - 1e-61 209.3 26.1 1.1e-61 209.1 26.1 1.0 1 0 0 1 1 1 1 Intermediate filament protein Phage_sheath_1C PF17482.2 KFO97507.1 - 0.038 14.0 1.3 0.091 12.7 0.1 2.1 2 1 0 2 2 2 0 Phage tail sheath C-terminal domain DUF4296 PF14129.6 KFO97507.1 - 0.051 14.2 1.9 0.74 10.5 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) YbaB_DNA_bd PF02575.16 KFO97507.1 - 0.46 10.8 4.5 8.2 6.7 0.8 3.4 4 0 0 4 4 3 0 YbaB/EbfC DNA-binding family ADIP PF11559.8 KFO97507.1 - 0.71 9.9 18.8 0.16 12.1 10.3 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF5344 PF17279.2 KFO97507.1 - 0.97 10.1 13.0 9.1 6.9 7.3 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5344) Tweety PF04906.13 KFO97507.1 - 1.1 7.9 5.3 1.1 7.9 4.0 1.6 1 1 1 2 2 2 0 Tweety CREPT PF16566.5 KFO97507.1 - 1.4 9.1 15.3 1 9.5 9.7 2.4 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour DUF4168 PF13767.6 KFO97507.1 - 1.5 10.1 9.6 1.4 10.1 0.6 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4168) DivIVA PF05103.13 KFO97507.1 - 1.9 8.6 15.7 9.5 6.3 0.1 2.7 1 1 1 2 2 2 0 DivIVA protein Exonuc_VII_L PF02601.15 KFO97507.1 - 3.4 7.2 12.9 1.2 8.7 10.4 1.5 1 1 1 2 2 2 0 Exonuclease VII, large subunit Fib_alpha PF08702.10 KFO97507.1 - 6.9 6.8 16.9 7.1 6.8 2.9 3.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family BST2 PF16716.5 KFO97507.1 - 8 7.1 14.6 18 6.0 0.8 3.4 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 Golgin_A5 PF09787.9 KFO97507.1 - 9.6 5.6 23.4 2.4 7.6 10.9 2.1 1 1 0 2 2 2 0 Golgin subfamily A member 5 Filament PF00038.21 KFO97508.1 - 5.2e-117 390.9 33.8 5.9e-117 390.7 33.8 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.12 KFO97508.1 - 4.6e-05 23.5 1.7 4.6e-05 23.5 1.7 3.7 3 1 1 4 4 4 1 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 KFO97508.1 - 0.00062 20.3 2.3 0.00062 20.3 2.3 3.9 3 1 1 4 4 4 1 Apg6 coiled-coil region DUF4407 PF14362.6 KFO97508.1 - 0.00065 19.1 16.3 0.029 13.7 8.3 3.0 1 1 2 3 3 3 2 Domain of unknown function (DUF4407) Atg14 PF10186.9 KFO97508.1 - 0.00094 18.4 9.7 0.0016 17.6 2.3 2.4 1 1 1 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 SPATA1_C PF15743.5 KFO97508.1 - 0.018 15.1 0.1 0.018 15.1 0.1 4.0 2 1 1 3 3 3 0 Spermatogenesis-associated C-terminus Fib_alpha PF08702.10 KFO97508.1 - 0.056 13.6 21.1 0.57 10.4 1.9 4.2 2 1 0 4 4 4 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 KFO97508.1 - 0.19 11.5 26.9 0.43 10.4 1.8 4.9 5 0 0 5 5 5 0 Septum formation initiator Spc7 PF08317.11 KFO97508.1 - 0.24 10.3 26.6 0.017 14.0 11.8 2.5 2 1 1 3 3 3 0 Spc7 kinetochore protein ADIP PF11559.8 KFO97508.1 - 0.49 10.5 24.7 0.79 9.8 1.1 4.3 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding FlxA PF14282.6 KFO97508.1 - 0.85 9.6 16.4 1.2 9.2 0.1 3.2 2 1 1 3 3 3 0 FlxA-like protein DUF1664 PF07889.12 KFO97508.1 - 0.92 9.6 19.7 0.62 10.1 2.0 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Glyco_hydro_46 PF01374.18 KFO97508.1 - 1.4 8.5 4.9 0.55 9.8 0.2 2.4 2 1 1 3 3 3 0 Glycosyl hydrolase family 46 DUF4446 PF14584.6 KFO97508.1 - 1.6 8.7 15.0 6.4 6.8 0.0 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF4446) Baculo_PEP_C PF04513.12 KFO97508.1 - 1.7 8.7 17.1 5.2 7.1 0.7 3.8 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF724 PF05266.14 KFO97508.1 - 2.9 7.7 18.2 1.7 8.5 0.7 3.4 3 1 1 4 4 3 0 Protein of unknown function (DUF724) Sec2p PF06428.11 KFO97508.1 - 3.1 7.8 24.9 0.14 12.2 0.6 4.3 4 1 0 4 4 4 0 GDP/GTP exchange factor Sec2p Golgin_A5 PF09787.9 KFO97508.1 - 3.6 7.0 25.0 8.7 5.7 6.5 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF4094 PF13334.6 KFO97508.1 - 4.1 7.9 8.0 1.8 9.1 0.6 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) GTP-bdg_M PF16360.5 KFO97508.1 - 7.2 7.3 8.1 8.4 7.1 0.5 3.6 2 1 1 3 3 3 0 GTP-binding GTPase Middle Region FlaC_arch PF05377.11 KFO97508.1 - 9.9 6.6 21.8 2.1 8.8 1.0 4.5 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) Filament PF00038.21 KFO97509.1 - 5.1e-117 390.9 22.5 5.7e-117 390.7 22.5 1.0 1 0 0 1 1 1 1 Intermediate filament protein Bacillus_HBL PF05791.11 KFO97509.1 - 0.0031 17.4 0.9 0.0031 17.4 0.9 3.0 1 1 1 3 3 3 1 Bacillus haemolytic enterotoxin (HBL) DUF4407 PF14362.6 KFO97509.1 - 0.012 15.0 14.3 0.074 12.4 5.7 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Myosin_tail_1 PF01576.19 KFO97509.1 - 0.018 12.9 21.1 0.0097 13.8 3.3 2.2 1 1 1 2 2 2 0 Myosin tail SAA PF00277.18 KFO97509.1 - 0.081 13.4 0.1 0.24 11.9 0.1 1.8 1 0 0 1 1 1 0 Serum amyloid A protein Baculo_PEP_C PF04513.12 KFO97509.1 - 0.09 12.8 11.3 0.91 9.6 0.5 3.6 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2551 PF10826.8 KFO97509.1 - 0.1 12.9 0.4 4.3 7.6 0.0 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF2551) FlxA PF14282.6 KFO97509.1 - 0.46 10.5 11.3 4.3 7.4 0.1 3.1 2 1 0 2 2 2 0 FlxA-like protein DUF1664 PF07889.12 KFO97509.1 - 0.79 9.8 12.8 8.2 6.5 0.1 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) ADIP PF11559.8 KFO97509.1 - 2 8.5 23.0 2.8 8.0 4.6 4.1 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Sec2p PF06428.11 KFO97509.1 - 2.1 8.4 23.4 1.6 8.7 2.7 4.5 4 2 1 5 5 5 0 GDP/GTP exchange factor Sec2p RasGAP_C PF03836.15 KFO97509.1 - 2.1 8.5 13.6 0.62 10.2 0.6 3.3 1 1 2 3 3 3 0 RasGAP C-terminus Atg14 PF10186.9 KFO97509.1 - 2.5 7.1 16.6 1.1 8.3 0.7 2.9 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prefoldin PF02996.17 KFO97509.1 - 2.9 7.8 14.4 0.37 10.7 4.8 3.7 3 1 0 3 3 3 0 Prefoldin subunit TPR_MLP1_2 PF07926.12 KFO97509.1 - 3 7.9 27.4 0.15 12.2 1.5 3.8 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KFO97509.1 - 3.9 6.3 24.2 2.2 7.1 4.1 3.0 1 1 0 2 2 2 0 Spc7 kinetochore protein T2SSM PF04612.12 KFO97509.1 - 4.7 7.3 8.6 9.9 6.2 1.8 3.5 2 2 2 4 4 4 0 Type II secretion system (T2SS), protein M PHA_gran_rgn PF09650.10 KFO97509.1 - 5.3 7.4 7.7 34 4.8 0.7 3.6 2 1 2 4 4 3 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) Snapin_Pallidin PF14712.6 KFO97509.1 - 6.5 7.3 11.9 6.1 7.3 0.6 4.3 4 0 0 4 4 4 0 Snapin/Pallidin APG6_N PF17675.1 KFO97509.1 - 8.5 6.9 29.5 0.069 13.7 1.8 3.8 3 1 1 4 4 4 0 Apg6 coiled-coil region DUF5082 PF16888.5 KFO97509.1 - 8.6 6.7 19.1 5.2 7.4 4.7 4.0 4 1 0 4 4 4 0 Domain of unknown function (DUF5082) GTP-bdg_M PF16360.5 KFO97509.1 - 9.5 6.9 11.8 14 6.4 0.3 3.4 3 0 0 3 3 3 0 GTP-binding GTPase Middle Region Filament PF00038.21 KFO97510.1 - 3.2e-86 289.7 22.5 8.4e-86 288.4 22.5 1.6 1 1 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.12 KFO97510.1 - 6.4e-05 23.0 2.8 6.4e-05 23.0 2.8 4.5 4 1 1 5 5 5 1 TPR/MLP1/MLP2-like protein SPATA1_C PF15743.5 KFO97510.1 - 0.0012 18.9 2.1 0.0012 18.9 2.1 3.0 3 1 0 3 3 3 1 Spermatogenesis-associated C-terminus DivIC PF04977.15 KFO97510.1 - 0.028 14.2 19.1 0.37 10.6 0.5 4.5 2 1 2 4 4 4 0 Septum formation initiator Selenoprotein_S PF06936.11 KFO97510.1 - 0.075 12.8 0.1 0.075 12.8 0.1 2.2 3 0 0 3 3 3 0 Selenoprotein S (SelS) ORF45 PF17620.2 KFO97510.1 - 0.12 12.5 0.6 0.18 11.9 0.6 1.2 1 0 0 1 1 1 0 Family of unknown function Lectin_N PF03954.14 KFO97510.1 - 2.1 8.1 5.8 1.6 8.5 0.1 2.7 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain Lzipper-MIP1 PF14389.6 KFO97510.1 - 2.3 8.6 0.0 2.3 8.6 0.0 4.0 5 0 0 5 5 5 0 Leucine-zipper of ternary complex factor MIP1 Wtap PF17098.5 KFO97510.1 - 5.8 6.8 13.2 1.7 8.6 7.1 2.9 2 1 0 2 2 2 0 WTAP/Mum2p family FlaC_arch PF05377.11 KFO97510.1 - 7.3 7.1 10.6 5.1 7.6 0.3 4.0 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) Filament PF00038.21 KFO97511.1 - 6.3e-100 334.8 36.5 7.2e-100 334.6 36.5 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.12 KFO97511.1 - 0.00025 21.1 2.7 0.00025 21.1 2.7 3.8 3 1 0 3 3 3 2 TPR/MLP1/MLP2-like protein ORF45 PF17620.2 KFO97511.1 - 0.11 12.6 0.7 0.17 12.0 0.7 1.2 1 0 0 1 1 1 0 Family of unknown function Lzipper-MIP1 PF14389.6 KFO97511.1 - 0.14 12.5 23.7 0.15 12.4 4.2 4.6 5 1 0 5 5 5 0 Leucine-zipper of ternary complex factor MIP1 DUF45 PF01863.17 KFO97511.1 - 1.5 8.8 7.4 1.2 9.1 0.1 2.9 2 1 2 4 4 4 0 Protein of unknown function DUF45 Tropomyosin_1 PF12718.7 KFO97511.1 - 1.8 8.7 27.5 0.51 10.5 9.1 3.4 2 1 0 3 3 3 0 Tropomyosin like ADIP PF11559.8 KFO97511.1 - 2.7 8.1 29.7 0.11 12.6 2.0 3.7 2 2 1 3 3 3 0 Afadin- and alpha -actinin-Binding Phage_GPO PF05929.11 KFO97511.1 - 4.7 6.8 11.2 3.1 7.3 5.6 2.4 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase SKA1 PF07160.12 KFO97511.1 - 5.6 6.7 19.3 0.12 12.3 7.4 3.2 2 2 2 4 4 4 0 Spindle and kinetochore-associated protein 1 GAS PF13851.6 KFO97511.1 - 6.5 6.0 32.1 19 4.6 12.1 4.2 2 2 1 3 3 3 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 KFO97511.1 - 6.6 6.7 40.2 4.3 7.4 7.8 4.2 2 2 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF883 PF05957.13 KFO97511.1 - 8.6 7.0 7.0 12 6.5 0.1 3.8 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) DUF4446 PF14584.6 KFO97511.1 - 9.7 6.2 14.3 0.6 10.1 0.4 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF4446) Filament PF00038.21 KFO97512.1 - 6.5e-98 328.2 31.8 7.3e-98 328.0 31.8 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.12 KFO97512.1 - 3.9e-08 33.4 26.2 1.4e-06 28.3 0.2 3.7 3 1 0 3 3 3 2 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 KFO97512.1 - 0.00083 18.9 26.0 0.0088 15.5 17.1 2.3 2 0 0 2 2 2 2 Golgin subfamily A member 5 Phage_GP20 PF06810.11 KFO97512.1 - 0.0015 18.3 11.7 0.0033 17.2 2.8 2.8 2 1 0 2 2 2 1 Phage minor structural protein GP20 DUF4407 PF14362.6 KFO97512.1 - 0.003 17.0 12.7 0.84 8.9 7.1 3.1 1 1 2 3 3 3 2 Domain of unknown function (DUF4407) Laminin_II PF06009.12 KFO97512.1 - 0.0056 16.7 6.1 0.0056 16.7 6.1 3.0 2 1 1 3 3 3 1 Laminin Domain II Tropomyosin_1 PF12718.7 KFO97512.1 - 0.008 16.3 11.1 0.008 16.3 11.1 3.4 2 1 0 3 3 3 1 Tropomyosin like Transcrip_act PF04949.13 KFO97512.1 - 0.0091 15.9 7.9 0.43 10.5 0.5 2.8 1 1 1 2 2 2 2 Transcriptional activator UPF0242 PF06785.11 KFO97512.1 - 0.025 14.7 26.8 0.52 10.4 1.9 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF720 PF05302.11 KFO97512.1 - 0.084 12.7 7.6 0.059 13.2 5.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF720) ADIP PF11559.8 KFO97512.1 - 0.21 11.6 25.3 0.18 11.9 10.2 4.0 2 2 2 4 4 4 0 Afadin- and alpha -actinin-Binding Lectin_N PF03954.14 KFO97512.1 - 0.24 11.2 11.8 5.5 6.7 4.7 3.4 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Bacillus_HBL PF05791.11 KFO97512.1 - 0.27 11.0 11.7 0.018 14.8 3.7 2.8 3 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Death PF00531.22 KFO97512.1 - 0.3 11.3 3.8 2.2 8.5 0.1 3.0 2 1 1 3 3 3 0 Death domain Exonuc_VII_L PF02601.15 KFO97512.1 - 0.39 10.2 16.8 0.061 12.9 7.7 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF2312 PF10073.9 KFO97512.1 - 0.54 9.9 0.0 0.54 9.9 0.0 3.1 4 1 0 4 4 3 0 Uncharacterized protein conserved in bacteria (DUF2312) Gp58 PF07902.11 KFO97512.1 - 0.61 8.3 11.3 1.1 7.4 11.1 1.7 1 1 0 1 1 1 0 gp58-like protein Spc7 PF08317.11 KFO97512.1 - 0.67 8.8 28.7 0.05 12.5 13.6 3.2 2 2 1 3 3 3 0 Spc7 kinetochore protein AAA_13 PF13166.6 KFO97512.1 - 0.84 8.2 15.9 1.9 7.0 15.1 1.8 1 1 0 1 1 1 0 AAA domain Atg14 PF10186.9 KFO97512.1 - 1.5 7.8 18.6 8.7 5.3 14.9 2.5 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 BLOC1_2 PF10046.9 KFO97512.1 - 1.6 9.1 21.8 5.6 7.3 0.2 4.8 3 2 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4446 PF14584.6 KFO97512.1 - 1.7 8.6 18.0 1.4 8.9 0.1 3.7 3 1 2 5 5 5 0 Protein of unknown function (DUF4446) DUF4200 PF13863.6 KFO97512.1 - 2 8.9 21.8 2.5 8.5 0.3 3.6 2 2 0 2 2 2 0 Domain of unknown function (DUF4200) Phage_Mu_Gam PF07352.12 KFO97512.1 - 2.3 8.1 18.8 8.4 6.3 1.5 4.3 3 1 1 4 4 4 0 Bacteriophage Mu Gam like protein CENP-F_leu_zip PF10473.9 KFO97512.1 - 2.4 8.2 35.0 7.2 6.6 0.6 4.3 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HAD_2 PF13419.6 KFO97512.1 - 2.4 8.2 7.0 5.7 7.0 0.1 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Phage_GPO PF05929.11 KFO97512.1 - 2.5 7.7 8.0 1.1 8.8 5.2 1.9 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase FapA PF03961.13 KFO97512.1 - 2.8 6.5 21.6 4.8 5.7 0.4 3.0 1 1 2 3 3 3 0 Flagellar Assembly Protein A POX PF07526.11 KFO97512.1 - 3.2 8.3 11.5 1.1 9.9 5.1 2.6 2 1 0 2 2 2 0 Associated with HOX DUF848 PF05852.11 KFO97512.1 - 3.5 7.7 14.6 0.64 10.1 6.5 3.4 1 1 2 4 4 4 0 Gammaherpesvirus protein of unknown function (DUF848) Syntaxin-6_N PF09177.11 KFO97512.1 - 6.1 7.5 16.1 35 5.0 7.1 3.7 2 2 1 3 3 3 0 Syntaxin 6, N-terminal PspA_IM30 PF04012.12 KFO97512.1 - 6.1 6.4 21.1 6.4 6.3 0.2 4.2 2 1 2 4 4 4 0 PspA/IM30 family DUF948 PF06103.11 KFO97512.1 - 6.2 7.1 9.8 2.7 8.3 0.5 3.8 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.13 KFO97512.1 - 7.7 5.7 15.3 1.4 8.1 8.2 2.6 2 1 0 2 2 2 0 TMPIT-like protein Fungal_TACC PF12709.7 KFO97512.1 - 7.8 7.0 24.1 0.75 10.3 3.7 5.1 3 2 1 5 5 5 0 Fungal Transforming acidic coiled-coil (TACC) proteins JIP_LZII PF16471.5 KFO97512.1 - 8 6.7 24.7 2.6 8.3 1.3 5.3 5 0 0 5 5 5 0 JNK-interacting protein leucine zipper II Cob_adeno_trans PF01923.18 KFO97512.1 - 8.5 6.5 8.4 2.7 8.1 1.1 2.9 1 1 1 2 2 2 0 Cobalamin adenosyltransferase HemX PF04375.14 KFO97512.1 - 9.3 5.4 18.9 1.1 8.5 9.4 2.9 2 1 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Filament PF00038.21 KFO97513.1 - 2e-92 310.1 33.2 2.2e-92 310.0 33.2 1.0 1 0 0 1 1 1 1 Intermediate filament protein Vps5 PF09325.10 KFO97513.1 - 0.0007 19.2 8.3 0.013 15.1 1.2 2.5 1 1 1 2 2 2 2 Vps5 C terminal like TPR_MLP1_2 PF07926.12 KFO97513.1 - 0.0024 17.9 1.4 0.0024 17.9 1.4 3.5 3 1 0 3 3 2 1 TPR/MLP1/MLP2-like protein DUF720 PF05302.11 KFO97513.1 - 0.0037 17.1 4.8 0.0037 17.1 4.8 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF720) ADIP PF11559.8 KFO97513.1 - 0.021 14.9 8.7 0.021 14.9 8.7 3.7 2 2 2 4 4 4 0 Afadin- and alpha -actinin-Binding Hema_stalk PF08720.10 KFO97513.1 - 0.031 14.0 0.1 0.39 10.4 0.0 2.5 2 1 1 3 3 3 0 Influenza C hemagglutinin stalk Lectin_N PF03954.14 KFO97513.1 - 0.032 14.0 13.3 0.48 10.2 1.6 3.5 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain Golgin_A5 PF09787.9 KFO97513.1 - 0.05 13.1 30.3 0.035 13.6 17.0 3.0 1 1 2 3 3 3 0 Golgin subfamily A member 5 DUF573 PF04504.14 KFO97513.1 - 0.057 14.1 0.8 0.36 11.5 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function, DUF573 DUF4200 PF13863.6 KFO97513.1 - 0.068 13.6 0.2 0.068 13.6 0.2 3.7 2 2 1 3 3 3 0 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.9 KFO97513.1 - 0.23 11.5 35.4 0.073 13.1 6.1 4.3 2 1 2 4 4 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Transcrip_act PF04949.13 KFO97513.1 - 0.24 11.3 10.5 0.043 13.7 2.4 2.7 1 1 2 3 3 3 0 Transcriptional activator T2SSM PF04612.12 KFO97513.1 - 0.41 10.7 8.7 3.2 7.8 0.0 2.9 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein M Bacillus_HBL PF05791.11 KFO97513.1 - 0.56 10.0 12.6 0.032 14.0 3.2 3.1 1 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Gp58 PF07902.11 KFO97513.1 - 0.78 8.0 12.7 0.27 9.5 8.0 1.9 1 1 1 2 2 2 0 gp58-like protein Spc7 PF08317.11 KFO97513.1 - 0.84 8.4 27.9 0.19 10.6 16.9 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein Phage_GPO PF05929.11 KFO97513.1 - 0.88 9.1 8.9 0.64 9.6 6.4 1.9 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase HAD_2 PF13419.6 KFO97513.1 - 1 9.4 7.1 1 9.4 0.1 2.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HMMR_N PF15905.5 KFO97513.1 - 1.1 8.7 28.7 0.11 12.0 21.7 2.1 1 1 1 2 2 1 0 Hyaluronan mediated motility receptor N-terminal DUF4407 PF14362.6 KFO97513.1 - 1.2 8.4 13.5 1.4 8.2 7.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) POX PF07526.11 KFO97513.1 - 1.3 9.6 7.4 1 9.9 4.6 2.1 2 0 0 2 2 2 0 Associated with HOX Tropomyosin_1 PF12718.7 KFO97513.1 - 1.4 9.1 25.4 0.054 13.7 10.3 3.5 1 1 1 3 3 3 0 Tropomyosin like TRAF_BIRC3_bd PF16673.5 KFO97513.1 - 2.2 8.1 6.8 1.3 8.9 1.9 2.7 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF3456 PF11938.8 KFO97513.1 - 2.9 8.4 8.6 12 6.4 2.8 2.4 1 1 1 2 2 2 0 TLR4 regulator and MIR-interacting MSAP Fungal_TACC PF12709.7 KFO97513.1 - 3 8.3 22.5 3.7 8.1 2.7 5.7 3 2 3 6 6 6 0 Fungal Transforming acidic coiled-coil (TACC) proteins Laminin_II PF06009.12 KFO97513.1 - 3.3 7.7 16.3 0.33 11.0 7.6 2.7 1 1 2 3 3 3 0 Laminin Domain II V_ATPase_I PF01496.19 KFO97513.1 - 7.4 4.3 14.6 0.24 9.2 7.7 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 KFO97513.1 - 8.9 6.4 13.9 1.8 8.6 3.3 3.5 1 1 3 5 5 5 0 Protein of unknown function (DUF1664) Filament PF00038.21 KFO97514.1 - 1.5e-103 346.7 25.6 1.7e-103 346.5 25.6 1.0 1 0 0 1 1 1 1 Intermediate filament protein CENP-F_leu_zip PF10473.9 KFO97514.1 - 3e-05 24.1 30.9 0.00041 20.4 5.5 4.8 3 2 1 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 KFO97514.1 - 3.1e-05 24.0 0.6 3.1e-05 24.0 0.6 3.7 3 1 0 3 3 3 1 TPR/MLP1/MLP2-like protein Nsp1_C PF05064.13 KFO97514.1 - 0.00089 19.1 6.3 0.00089 19.1 6.3 3.4 2 2 1 3 3 3 1 Nsp1-like C-terminal region SPATA1_C PF15743.5 KFO97514.1 - 0.0025 17.9 16.7 0.084 12.9 0.1 2.9 2 1 0 2 2 2 1 Spermatogenesis-associated C-terminus ADIP PF11559.8 KFO97514.1 - 0.0055 16.8 26.4 0.21 11.7 0.9 4.0 3 1 1 4 4 4 2 Afadin- and alpha -actinin-Binding Prefoldin_2 PF01920.20 KFO97514.1 - 0.0071 16.3 19.2 0.89 9.5 1.8 4.9 3 1 1 4 4 4 1 Prefoldin subunit DUF5344 PF17279.2 KFO97514.1 - 0.021 15.4 10.0 0.27 11.8 3.2 3.9 2 2 2 4 4 4 0 Family of unknown function (DUF5344) MAD PF05557.13 KFO97514.1 - 0.029 12.8 22.8 0.051 11.9 1.2 3.1 2 1 1 3 3 3 0 Mitotic checkpoint protein Baculo_PEP_C PF04513.12 KFO97514.1 - 0.071 13.1 15.5 0.33 11.0 2.6 3.5 3 1 1 4 4 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus RasGAP_C PF03836.15 KFO97514.1 - 0.075 13.2 15.0 0.51 10.5 0.3 3.1 2 1 1 3 3 3 0 RasGAP C-terminus DUF4200 PF13863.6 KFO97514.1 - 0.12 12.8 17.3 0.26 11.7 0.4 3.4 2 2 2 4 4 4 0 Domain of unknown function (DUF4200) Spc7 PF08317.11 KFO97514.1 - 0.13 11.1 27.3 0.047 12.6 14.0 2.8 1 1 1 2 2 2 0 Spc7 kinetochore protein FlaC_arch PF05377.11 KFO97514.1 - 0.2 12.0 11.8 1.4 9.3 0.2 4.6 4 2 0 4 4 4 0 Flagella accessory protein C (FlaC) SKA1 PF07160.12 KFO97514.1 - 0.49 10.2 16.9 0.94 9.3 2.2 3.6 3 1 1 4 4 4 0 Spindle and kinetochore-associated protein 1 DUF4140 PF13600.6 KFO97514.1 - 0.52 10.8 14.7 3 8.4 1.9 3.9 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) Fungal_TACC PF12709.7 KFO97514.1 - 0.88 10.1 17.5 3.9 8.0 2.7 4.7 4 2 1 5 5 5 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF745 PF05335.13 KFO97514.1 - 1 9.0 10.6 7.6 6.2 7.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF745) TMF_DNA_bd PF12329.8 KFO97514.1 - 1.5 8.9 12.7 3.4 7.7 0.2 4.4 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding Golgin_A5 PF09787.9 KFO97514.1 - 1.6 8.1 25.5 1.3 8.4 13.8 2.7 1 1 1 2 2 2 0 Golgin subfamily A member 5 TBCC_N PF16752.5 KFO97514.1 - 2.3 8.7 8.5 14 6.2 2.4 3.0 2 1 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain CREPT PF16566.5 KFO97514.1 - 2.4 8.3 20.7 0.074 13.2 7.1 3.3 3 2 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour DUF4510 PF14971.6 KFO97514.1 - 2.7 8.3 8.4 0.33 11.3 1.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4510) Tropomyosin_1 PF12718.7 KFO97514.1 - 4 7.6 23.3 2.1 8.5 9.5 3.4 3 1 0 3 3 3 0 Tropomyosin like DUF4407 PF14362.6 KFO97514.1 - 4.5 6.5 18.2 5.5 6.3 6.4 2.9 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) Jnk-SapK_ap_N PF09744.9 KFO97514.1 - 5.2 7.3 29.5 0.44 10.8 2.8 3.5 2 2 2 4 4 4 0 JNK_SAPK-associated protein-1 PI3K_P85_iSH2 PF16454.5 KFO97514.1 - 5.3 6.6 22.4 1.7 8.2 1.8 3.9 3 1 1 4 4 4 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain APG6_N PF17675.1 KFO97514.1 - 6.3 7.3 33.3 0.48 11.0 2.7 4.1 2 2 2 4 4 4 0 Apg6 coiled-coil region KELK PF15796.5 KFO97514.1 - 6.7 7.3 15.6 0.083 13.4 4.0 3.3 3 1 0 3 3 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TolA_bind_tri PF16331.5 KFO97514.1 - 8.2 6.6 29.7 0.14 12.3 3.2 4.9 4 1 1 5 5 5 0 TolA binding protein trimerisation Uso1_p115_C PF04871.13 KFO97514.1 - 8.4 6.8 20.0 0.4 11.1 6.5 3.0 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1664 PF07889.12 KFO97514.1 - 9.6 6.3 13.0 8.5 6.4 0.5 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Filament PF00038.21 KFO97515.1 - 1.6e-105 353.2 25.3 1.8e-105 353.0 25.3 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.12 KFO97515.1 - 2.7e-05 24.3 24.9 0.00022 21.3 0.6 3.4 3 1 0 3 3 3 2 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 KFO97515.1 - 0.00034 20.7 33.3 0.027 14.5 14.7 5.0 3 2 2 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SPATA1_C PF15743.5 KFO97515.1 - 0.019 15.0 18.8 0.083 13.0 0.0 3.2 2 1 0 2 2 2 0 Spermatogenesis-associated C-terminus MAD PF05557.13 KFO97515.1 - 0.02 13.3 23.5 0.098 11.0 2.8 2.7 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF4140 PF13600.6 KFO97515.1 - 0.044 14.2 16.0 2.2 8.8 3.0 3.9 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) Baculo_PEP_C PF04513.12 KFO97515.1 - 0.096 12.7 9.7 0.065 13.3 2.2 2.8 3 0 0 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus gp45-slide_C PF09116.10 KFO97515.1 - 0.13 12.4 0.1 4.1 7.5 0.0 2.4 2 0 0 2 2 2 0 gp45 sliding clamp, C terminal DUF4200 PF13863.6 KFO97515.1 - 0.18 12.2 18.3 0.43 11.0 0.3 3.7 2 2 1 3 3 3 0 Domain of unknown function (DUF4200) CCDC144C PF14915.6 KFO97515.1 - 0.25 10.4 24.4 0.35 9.9 1.6 3.6 3 1 1 4 4 4 0 CCDC144C protein coiled-coil region APG6_N PF17675.1 KFO97515.1 - 0.28 11.7 29.1 0.086 13.4 0.7 3.8 3 1 1 4 4 4 0 Apg6 coiled-coil region Fungal_TACC PF12709.7 KFO97515.1 - 0.37 11.2 17.8 1.4 9.4 2.7 4.7 4 2 1 5 5 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins HAP2-GCS1 PF10699.9 KFO97515.1 - 0.55 10.3 3.0 11 6.1 0.1 3.1 3 0 0 3 3 3 0 Male gamete fusion factor DUF5344 PF17279.2 KFO97515.1 - 0.56 10.8 6.7 26 5.5 2.6 3.4 2 2 1 3 3 3 0 Family of unknown function (DUF5344) Prefoldin_2 PF01920.20 KFO97515.1 - 0.63 10.0 24.6 4.5 7.3 1.3 4.9 4 1 1 5 5 4 0 Prefoldin subunit Nsp1_C PF05064.13 KFO97515.1 - 0.65 9.8 17.9 0.051 13.4 7.3 3.2 2 2 1 3 3 3 0 Nsp1-like C-terminal region DUF4407 PF14362.6 KFO97515.1 - 0.66 9.3 16.3 2.4 7.4 4.8 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 KFO97515.1 - 0.84 8.5 25.4 1.6 7.5 15.1 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.8 KFO97515.1 - 0.93 9.6 26.8 0.52 10.4 1.6 4.3 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 KFO97515.1 - 1 8.8 24.8 2.4 7.5 14.7 2.6 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF4510 PF14971.6 KFO97515.1 - 1.4 9.3 9.5 0.14 12.5 2.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4510) SKA1 PF07160.12 KFO97515.1 - 1.5 8.7 16.4 3.9 7.2 8.0 3.3 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 Jnk-SapK_ap_N PF09744.9 KFO97515.1 - 2 8.7 30.1 1.5 9.0 10.6 3.3 2 1 2 4 4 4 0 JNK_SAPK-associated protein-1 Phage_GP20 PF06810.11 KFO97515.1 - 3.1 7.6 12.9 16 5.3 5.9 3.9 2 2 0 2 2 2 0 Phage minor structural protein GP20 DUF3138 PF11336.8 KFO97515.1 - 3.8 6.0 4.0 3.6 6.1 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) DUF641 PF04859.12 KFO97515.1 - 4.5 7.6 18.7 1.4 9.2 0.8 3.5 2 2 1 3 3 3 0 Plant protein of unknown function (DUF641) FlxA PF14282.6 KFO97515.1 - 4.5 7.3 21.8 1.1 9.3 10.7 3.7 2 2 0 3 3 3 0 FlxA-like protein DHR10 PF18595.1 KFO97515.1 - 4.8 7.3 27.4 1.3 9.2 2.0 3.3 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain NPV_P10 PF05531.12 KFO97515.1 - 4.9 7.7 10.9 12 6.4 1.0 3.8 3 1 1 4 4 3 0 Nucleopolyhedrovirus P10 protein Swi5 PF07061.11 KFO97515.1 - 5.9 7.1 11.0 4.9 7.3 0.4 4.0 4 0 0 4 4 3 0 Swi5 Bacillus_HBL PF05791.11 KFO97515.1 - 6 6.6 8.5 1.3 8.9 3.2 2.4 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) RasGAP_C PF03836.15 KFO97515.1 - 6.2 7.0 12.2 0.41 10.8 0.2 3.1 2 1 0 2 2 2 0 RasGAP C-terminus TolA_bind_tri PF16331.5 KFO97515.1 - 6.3 6.9 30.1 0.12 12.4 2.7 5.0 5 1 1 6 6 4 0 TolA binding protein trimerisation Cortex-I_coil PF09304.10 KFO97515.1 - 6.7 7.0 18.8 15 5.8 1.1 4.1 3 1 1 4 4 4 0 Cortexillin I, coiled coil DivIC PF04977.15 KFO97515.1 - 7.2 6.5 21.3 6 6.7 0.2 5.0 5 0 0 5 5 5 0 Septum formation initiator Filament PF00038.21 KFO97516.1 - 2.9e-98 329.3 22.4 3.2e-98 329.1 22.4 1.0 1 0 0 1 1 1 1 Intermediate filament protein CENP-F_leu_zip PF10473.9 KFO97516.1 - 0.00089 19.3 28.9 0.091 12.8 10.3 4.1 3 1 1 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PSI_PsaF PF02507.15 KFO97516.1 - 0.075 12.9 0.7 10 5.9 0.4 2.4 2 0 0 2 2 2 0 Photosystem I reaction centre subunit III SlyX PF04102.12 KFO97516.1 - 0.082 13.5 21.1 1.7 9.3 3.4 4.9 4 1 2 6 6 5 0 SlyX CREPT PF16566.5 KFO97516.1 - 0.084 13.0 16.7 0.35 11.0 10.1 3.1 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour MitMem_reg PF13012.6 KFO97516.1 - 0.19 12.1 4.5 0.99 9.8 2.6 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function TPR_MLP1_2 PF07926.12 KFO97516.1 - 0.2 11.7 23.6 1.1 9.4 13.6 3.4 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein MADF_DNA_bdg PF10545.9 KFO97516.1 - 0.29 11.5 8.1 0.36 11.2 0.2 3.6 3 1 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Spc7 PF08317.11 KFO97516.1 - 0.57 9.0 26.0 0.47 9.3 18.2 3.1 3 1 0 3 3 3 0 Spc7 kinetochore protein Fungal_TACC PF12709.7 KFO97516.1 - 0.97 9.9 19.5 6.9 7.2 2.7 4.5 4 1 1 5 5 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins HR1 PF02185.16 KFO97516.1 - 1 9.5 12.2 13 6.0 2.8 3.3 1 1 1 2 2 2 0 Hr1 repeat Prefoldin_2 PF01920.20 KFO97516.1 - 1.2 9.1 22.0 5.5 7.0 1.8 4.9 4 1 1 5 5 4 0 Prefoldin subunit Spectrin PF00435.21 KFO97516.1 - 1.5 9.4 13.9 0.3 11.6 8.3 2.8 3 1 1 4 4 3 0 Spectrin repeat ADIP PF11559.8 KFO97516.1 - 1.7 8.8 24.4 25 4.9 0.1 4.2 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding Phage_GPO PF05929.11 KFO97516.1 - 2 8.0 7.7 1.7 8.2 5.4 2.1 1 1 2 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Mt_ATP-synt_D PF05873.12 KFO97516.1 - 2.9 7.7 11.1 2.6 7.9 5.2 3.2 3 1 0 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) FlxA PF14282.6 KFO97516.1 - 3.1 7.8 19.5 0.96 9.5 10.8 3.6 3 1 0 3 3 3 0 FlxA-like protein FlaC_arch PF05377.11 KFO97516.1 - 4.2 7.8 9.1 34 4.9 0.2 3.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF745 PF05335.13 KFO97516.1 - 4.3 7.0 10.1 9.5 5.9 10.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Nsp1_C PF05064.13 KFO97516.1 - 5.2 6.9 17.8 0.14 12.0 9.4 2.6 2 1 1 3 3 3 0 Nsp1-like C-terminal region Latarcin PF10279.9 KFO97516.1 - 8.9 6.8 7.7 5.1 7.6 0.4 3.3 3 1 0 3 3 3 0 Latarcin precursor Filament PF00038.21 KFO97517.1 - 2.8e-112 375.4 21.4 3.1e-112 375.2 21.4 1.0 1 0 0 1 1 1 1 Intermediate filament protein Peptidase_Mx PF15887.5 KFO97517.1 - 0.069 12.6 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase YdaS_antitoxin PF15943.5 KFO97517.1 - 0.074 12.9 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT FapA PF03961.13 KFO97517.1 - 0.12 10.9 10.7 1.2 7.7 3.4 2.7 1 1 2 3 3 3 0 Flagellar Assembly Protein A SDH_beta PF03315.15 KFO97517.1 - 0.35 11.2 0.1 0.35 11.2 0.1 2.1 2 1 1 3 3 2 0 Serine dehydratase beta chain SlyX PF04102.12 KFO97517.1 - 0.48 11.1 20.7 8.8 7.0 1.1 5.4 5 1 1 6 6 5 0 SlyX DUF4446 PF14584.6 KFO97517.1 - 0.58 10.1 6.1 2.4 8.1 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) APG6_N PF17675.1 KFO97517.1 - 1.9 9.0 25.1 0.18 12.3 1.4 3.4 3 0 0 3 3 3 0 Apg6 coiled-coil region DUF5344 PF17279.2 KFO97517.1 - 2.5 8.7 8.8 18 6.0 0.0 4.0 4 1 0 4 4 4 0 Family of unknown function (DUF5344) Atg14 PF10186.9 KFO97517.1 - 3.5 6.6 11.1 1.7 7.7 0.8 2.6 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlxA PF14282.6 KFO97517.1 - 3.5 7.7 11.2 6 6.9 0.2 3.5 2 1 2 4 4 4 0 FlxA-like protein RasGAP_C PF03836.15 KFO97517.1 - 3.9 7.6 9.2 1.9 8.6 2.2 3.1 2 1 0 3 3 3 0 RasGAP C-terminus XhlA PF10779.9 KFO97517.1 - 6.2 7.1 5.8 2.8 8.2 0.8 2.8 2 0 0 2 2 2 0 Haemolysin XhlA Filament PF00038.21 KFO97518.1 - 5.8e-112 374.3 19.2 6.7e-112 374.1 19.2 1.0 1 0 0 1 1 1 1 Intermediate filament protein DUF4407 PF14362.6 KFO97518.1 - 0.01 15.2 9.0 0.75 9.1 1.9 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Peptidase_Mx PF15887.5 KFO97518.1 - 0.098 12.0 0.2 0.17 11.2 0.2 1.3 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase Atg14 PF10186.9 KFO97518.1 - 0.18 10.9 9.8 1.3 8.1 1.8 2.5 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Keratin_2_head PF16208.5 KFO97518.1 - 0.29 11.3 45.9 0.47 10.6 45.9 1.3 1 0 0 1 1 1 0 Keratin type II head DUF4446 PF14584.6 KFO97518.1 - 0.36 10.8 6.8 3.1 7.8 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) DUF5344 PF17279.2 KFO97518.1 - 0.48 11.0 4.0 23 5.6 0.0 4.0 3 1 0 3 3 3 0 Family of unknown function (DUF5344) DUF1664 PF07889.12 KFO97518.1 - 0.81 9.7 10.1 13 5.9 0.7 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 KFO97518.1 - 0.99 9.6 16.2 3.3 7.9 3.4 3.4 3 0 0 3 3 3 0 Tropomyosin like CC2-LZ PF16516.5 KFO97518.1 - 2 8.8 13.1 1.5 9.2 0.4 3.3 3 1 0 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator RasGAP_C PF03836.15 KFO97518.1 - 2.8 8.1 12.3 1.8 8.7 1.3 3.5 3 1 1 4 4 4 0 RasGAP C-terminus FapA PF03961.13 KFO97518.1 - 3.3 6.2 8.2 6.9 5.2 4.3 2.6 1 1 2 3 3 3 0 Flagellar Assembly Protein A WXG100 PF06013.12 KFO97518.1 - 3.6 7.9 6.5 1.6 9.0 0.3 3.2 2 1 2 4 4 4 0 Proteins of 100 residues with WXG Fib_alpha PF08702.10 KFO97518.1 - 8.6 6.5 12.4 14 5.8 1.9 3.8 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family HIP1_clath_bdg PF16515.5 KFO97518.1 - 9.2 6.9 13.0 5.3 7.7 2.5 3.3 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Arm PF00514.23 KFO97519.1 - 5.9e-48 159.5 18.2 1.2e-09 37.9 0.1 11.2 12 0 0 12 12 12 6 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KFO97519.1 - 4.6e-09 35.8 7.9 0.15 12.4 0.0 7.0 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.6 KFO97519.1 - 5.9e-08 33.1 9.8 1.1 9.8 0.0 7.6 7 1 1 8 8 8 3 HEAT-like repeat Cnd1 PF12717.7 KFO97519.1 - 3.2e-07 30.5 1.3 0.00076 19.6 0.2 3.8 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFO97519.1 - 6.2e-07 29.7 11.7 0.0013 19.1 0.6 6.3 4 3 2 6 6 6 1 HEAT repeats Adaptin_N PF01602.20 KFO97519.1 - 8.5e-07 27.9 8.0 0.00018 20.3 1.3 3.0 2 1 0 2 2 2 2 Adaptin N terminal region V-ATPase_H_N PF03224.14 KFO97519.1 - 2.5e-06 27.0 1.6 0.061 12.6 0.1 3.7 1 1 1 3 3 3 3 V-ATPase subunit H DUF3361 PF11841.8 KFO97519.1 - 0.00017 21.5 5.0 0.2 11.6 0.2 5.0 3 2 2 6 6 6 1 Domain of unknown function (DUF3361) Atx10homo_assoc PF09759.9 KFO97519.1 - 0.00043 20.3 4.4 0.017 15.1 0.1 4.9 5 2 2 7 7 7 1 Spinocerebellar ataxia type 10 protein domain RasGEF_N_2 PF14663.6 KFO97519.1 - 0.00059 20.2 6.3 3.6 8.0 0.2 5.1 4 1 1 5 5 5 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain PUL PF08324.11 KFO97519.1 - 0.0024 17.1 0.2 0.0024 17.1 0.2 2.2 2 1 0 2 2 2 1 PUL domain Arm_2 PF04826.13 KFO97519.1 - 0.0038 16.7 5.7 0.99 8.8 0.1 4.9 4 2 2 6 6 6 1 Armadillo-like FKBP_C PF00254.28 KFO97520.1 - 1.9e-102 335.8 0.0 1.3e-28 99.2 0.0 4.2 4 0 0 4 4 4 4 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_1 PF00036.32 KFO97520.1 - 4.2e-08 32.2 0.4 0.00074 18.9 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KFO97520.1 - 8.7e-08 31.3 1.4 0.00064 19.1 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFO97520.1 - 2.5e-06 27.8 0.2 0.023 15.2 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFO97520.1 - 1.6e-05 24.4 0.1 0.11 12.5 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KFO97520.1 - 0.00066 19.5 0.1 0.0013 18.6 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair UMPH-1 PF05822.12 KFO97521.1 - 6.4e-120 399.2 0.4 7.5e-120 399.0 0.4 1.0 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 KFO97521.1 - 6.1e-05 23.5 0.0 0.00026 21.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DNA_photolyase PF00875.18 KFO97521.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 DNA photolyase BACK PF07707.15 KFO97522.1 - 4.1e-28 97.5 3.1 3.7e-27 94.4 1.7 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFO97522.1 - 1.9e-19 69.2 1.4 5.5e-05 23.3 0.0 4.9 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KFO97522.1 - 1.3e-12 47.1 14.2 0.0023 17.5 0.4 5.7 6 1 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 KFO97522.1 - 2.8e-12 46.4 0.0 0.32 11.0 0.0 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain BTB PF00651.31 KFO97522.1 - 8e-07 29.3 0.1 3.4e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 KFO97522.1 - 1.4e-06 28.1 2.2 1.1 9.3 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 KFO97522.1 - 1.8e-06 28.1 0.1 0.019 15.2 0.0 4.5 5 0 0 5 5 5 1 Galactose oxidase, central domain LVIVD PF08309.11 KFO97522.1 - 0.26 10.7 1.2 15 5.0 0.3 2.5 2 0 0 2 2 2 0 LVIVD repeat Kelch_5 PF13854.6 KFO97522.1 - 9.7 6.3 8.3 15 5.7 0.0 3.8 4 0 0 4 4 4 0 Kelch motif Citrate_bind PF16114.5 KFO97523.1 - 3.2e-91 303.6 0.1 5.3e-91 302.9 0.1 1.4 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 KFO97523.1 - 4.1e-23 82.0 0.0 5.1e-20 71.9 0.0 3.0 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 KFO97523.1 - 2.6e-13 50.1 0.0 5.6e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 KFO97523.1 - 4.7e-11 43.2 0.0 1.1e-10 42.1 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 KFO97523.1 - 4.9e-08 32.8 0.0 9.5e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 KFO97523.1 - 0.00038 20.3 0.0 0.0042 16.9 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_5 PF13549.6 KFO97523.1 - 0.048 13.1 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain TPR_2 PF07719.17 KFO97524.1 - 9e-23 78.5 16.8 0.0015 18.5 0.0 7.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 KFO97524.1 - 2.1e-22 78.0 14.5 0.0012 18.6 0.1 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 KFO97524.1 - 1.3e-19 70.3 16.3 2e-06 28.0 0.1 5.6 3 2 5 8 8 8 6 Tetratricopeptide repeat TPR_MalT PF17874.1 KFO97524.1 - 8e-11 41.9 1.3 8e-11 41.9 1.3 1.8 2 1 0 2 2 2 1 MalT-like TPR region TPR_7 PF13176.6 KFO97524.1 - 5.2e-10 38.6 8.6 0.13 12.4 0.0 6.8 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFO97524.1 - 9.6e-09 34.8 16.2 0.34 11.2 0.1 7.2 8 0 0 8 8 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO97524.1 - 7.9e-06 26.0 10.6 0.071 13.3 0.1 4.0 2 2 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KFO97524.1 - 1.5e-05 25.6 8.6 0.076 13.7 0.0 5.1 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFO97524.1 - 0.00018 21.1 10.2 0.012 15.3 0.1 5.8 7 0 0 7 7 7 1 TPR repeat TPR_6 PF13174.6 KFO97524.1 - 0.0012 19.3 8.0 25 5.8 0.0 6.3 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFO97524.1 - 0.004 17.9 7.6 19 6.4 0.1 6.4 5 3 3 8 8 6 0 Tetratricopeptide repeat RPN7 PF10602.9 KFO97524.1 - 0.0046 16.7 2.8 0.36 10.5 0.3 3.5 2 2 1 3 3 3 1 26S proteasome subunit RPN7 DUF3856 PF12968.7 KFO97524.1 - 0.017 15.2 3.9 15 5.7 0.0 4.9 4 3 1 5 5 4 0 Domain of Unknown Function (DUF3856) ANAPC5 PF12862.7 KFO97524.1 - 0.019 15.0 0.4 1.8 8.7 0.0 3.7 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 5 SRF-TF PF00319.18 KFO97524.1 - 0.023 14.2 0.0 0.067 12.7 0.0 1.7 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) TPR_9 PF13371.6 KFO97524.1 - 0.032 14.4 7.2 0.25 11.5 0.1 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFO97524.1 - 0.032 14.1 10.7 3.2 7.7 0.0 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFO97524.1 - 0.052 14.1 13.1 0.55 10.8 0.7 5.1 3 3 2 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFO97524.1 - 0.075 13.5 8.8 58 4.4 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.20 KFO97524.1 - 0.09 13.1 0.2 1.1e+02 3.4 0.0 4.2 4 0 0 4 4 3 0 PPR repeat DUF2225 PF09986.9 KFO97524.1 - 0.16 11.6 5.4 0.14 11.9 1.9 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) CNPase PF05881.12 KFO97525.1 - 3.5e-114 380.2 0.1 4.9e-114 379.7 0.1 1.2 1 0 0 1 1 1 1 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) AAA_14 PF13173.6 KFO97525.1 - 2.2e-05 24.5 0.3 0.0017 18.4 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KFO97525.1 - 2.4e-05 24.5 0.0 7.1e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain 6PF2K PF01591.18 KFO97525.1 - 0.00021 20.7 0.1 0.056 12.7 0.1 2.2 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_22 PF13401.6 KFO97525.1 - 0.00026 21.3 0.5 0.014 15.7 0.4 2.8 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KFO97525.1 - 0.00027 21.4 0.0 0.00068 20.2 0.0 1.7 2 0 0 2 2 2 1 ABC transporter Zeta_toxin PF06414.12 KFO97525.1 - 0.0004 19.7 0.0 0.00077 18.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 KFO97525.1 - 0.001 19.5 0.2 0.0082 16.5 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.29 KFO97525.1 - 0.0031 17.9 0.0 0.0087 16.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFO97525.1 - 0.0035 17.3 0.0 0.01 15.8 0.0 1.8 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KFO97525.1 - 0.0037 16.5 0.5 0.097 11.8 0.5 2.4 1 1 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 KFO97525.1 - 0.004 17.7 0.0 0.0076 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain tRNA_lig_kinase PF08303.11 KFO97525.1 - 0.0071 16.5 0.1 0.012 15.7 0.1 1.3 1 0 0 1 1 1 1 tRNA ligase kinase domain Sigma54_activat PF00158.26 KFO97525.1 - 0.021 14.5 0.0 0.11 12.2 0.0 2.1 3 0 0 3 3 2 0 Sigma-54 interaction domain CPT PF07931.12 KFO97525.1 - 0.026 14.4 0.0 0.067 13.0 0.0 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein T2SSE PF00437.20 KFO97525.1 - 0.029 13.4 0.1 1.7 7.6 0.0 2.2 1 1 1 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 KFO97525.1 - 0.03 14.3 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 KFO97525.1 - 0.04 13.6 0.0 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KFO97525.1 - 0.064 13.7 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 KFO97525.1 - 0.075 12.5 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Tk-SP_N-pro PF18237.1 KFO97525.1 - 0.11 12.6 0.3 0.44 10.6 0.1 2.1 2 0 0 2 2 1 0 Tk-SP N-propeptide domain RsgA_GTPase PF03193.16 KFO97525.1 - 0.11 12.4 0.0 1.7 8.5 0.0 2.2 1 1 1 2 2 2 0 RsgA GTPase ATP_bind_1 PF03029.17 KFO97525.1 - 0.12 12.1 0.0 0.36 10.6 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TK PF00265.18 KFO97525.1 - 0.12 12.2 0.3 0.21 11.4 0.3 1.3 1 0 0 1 1 1 0 Thymidine kinase Viral_helicase1 PF01443.18 KFO97525.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 KFO97525.1 - 0.14 11.9 0.6 0.34 10.7 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KFO97525.1 - 0.15 12.6 0.4 1.1 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain TPR_2 PF07719.17 KFO97526.1 - 1.4e-20 71.7 6.7 1.4e-06 27.9 1.6 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 KFO97526.1 - 1.4e-20 72.2 8.3 7e-07 28.8 3.8 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFO97526.1 - 1.4e-10 40.7 4.8 2.4e-07 30.3 5.0 3.4 2 1 2 4 4 4 2 TPR repeat TPR_8 PF13181.6 KFO97526.1 - 7e-10 38.3 3.0 0.001 19.1 0.9 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFO97526.1 - 7.3e-10 39.0 5.8 2.9e-06 27.5 1.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFO97526.1 - 1.2e-09 38.5 0.5 0.01 16.3 0.1 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFO97526.1 - 1.5e-09 37.8 0.3 0.022 15.5 0.0 4.2 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFO97526.1 - 5.5e-09 35.8 5.0 1.1e-05 25.5 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFO97526.1 - 5.7e-08 33.3 2.5 0.0033 18.0 0.5 3.3 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFO97526.1 - 2.9e-06 27.5 4.2 0.12 13.1 0.3 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFO97526.1 - 3.2e-06 27.2 0.5 0.26 11.5 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO97526.1 - 1.8e-05 24.9 8.1 0.079 13.2 1.4 3.2 1 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KFO97526.1 - 0.00033 20.4 6.0 0.16 11.9 0.4 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 KFO97526.1 - 0.00062 20.1 1.7 0.54 11.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFO97526.1 - 0.00088 19.1 1.9 2.1 8.6 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.12 KFO97526.1 - 0.01 15.8 3.4 0.085 12.9 3.8 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KFO97526.1 - 0.017 15.6 1.7 16 5.9 0.1 2.9 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation TPR_15 PF13429.6 KFO97526.1 - 0.093 11.9 1.7 3.4 6.8 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFO97526.1 - 0.13 12.4 4.8 3.5 7.8 0.1 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 KFO97526.1 - 0.58 10.3 5.8 0.48 10.5 2.7 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Ras PF00071.22 KFO97527.1 - 1e-18 67.5 0.1 1.1e-18 67.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KFO97527.1 - 0.00024 20.6 0.1 0.00027 20.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFO97527.1 - 0.00031 21.0 0.0 0.00068 19.8 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF2121 PF09894.9 KFO97527.1 - 0.0022 17.6 0.1 0.0091 15.6 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2121) DUF2677 PF10838.8 KFO97527.1 - 0.067 13.1 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2677) GTP_EFTU PF00009.27 KFO97527.1 - 0.087 12.3 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain zf-met PF12874.7 KFO97528.1 - 4.1e-30 103.3 28.2 8.3e-08 32.4 0.5 5.1 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFO97528.1 - 1.2e-19 70.1 30.3 6.8e-06 26.2 2.2 5.4 5 1 1 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFO97528.1 - 2.1e-08 34.4 21.5 0.0036 17.6 0.3 4.3 4 0 0 4 4 4 4 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.12 KFO97528.1 - 1.3e-07 32.1 5.3 0.054 13.7 0.1 4.2 4 0 0 4 4 4 3 A-kinase anchoring protein 95 (AKAP95) zf-U1 PF06220.12 KFO97528.1 - 9.5e-06 25.3 14.6 0.11 12.3 0.1 4.3 4 0 0 4 4 4 3 U1 zinc finger zf-C2H2_9 PF16293.5 KFO97528.1 - 6e-05 22.8 8.5 0.46 10.4 0.1 4.3 4 0 0 4 4 4 2 C2H2 type zinc-finger (1 copy) DUF3449 PF11931.8 KFO97528.1 - 0.012 15.4 6.1 5.6 6.7 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) zf-C2H2_4 PF13894.6 KFO97528.1 - 0.013 16.3 14.0 1.4 9.9 0.6 4.9 5 0 0 5 5 5 0 C2H2-type zinc finger ZF-HD_dimer PF04770.12 KFO97528.1 - 0.013 15.8 0.2 1 9.7 0.0 3.4 3 0 0 3 3 3 0 ZF-HD protein dimerisation region zf-C2H2 PF00096.26 KFO97528.1 - 0.14 12.6 21.1 1.1 9.9 0.4 4.8 6 0 0 6 6 4 0 Zinc finger, C2H2 type zf-RRPl_C4 PF17026.5 KFO97528.1 - 0.2 11.8 7.2 3.3 7.9 0.1 3.7 4 0 0 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type zf_C2H2_ZHX PF18387.1 KFO97528.1 - 0.53 10.0 10.1 0.8 9.4 0.8 2.9 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-RING_7 PF02591.15 KFO97528.1 - 0.92 9.7 5.9 4.5 7.5 0.1 3.7 4 0 0 4 4 4 0 C4-type zinc ribbon domain Actin_micro PF17003.5 KFO97528.1 - 1.4 8.0 10.2 1.5 8.0 0.2 3.5 4 0 0 4 4 4 0 Putative actin-like family zinc_ribbon_15 PF17032.5 KFO97528.1 - 1.5 9.6 10.7 40 5.1 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon family zf-piccolo PF05715.13 KFO97528.1 - 2.4 8.4 8.0 18 5.6 0.1 3.9 4 0 0 4 4 4 0 Piccolo Zn-finger DUF4451 PF14616.6 KFO97528.1 - 2.6 8.3 12.7 1.4 9.1 3.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4451) RIG-I_C-RD PF11648.8 KFO97529.1 - 2.6e-38 130.8 1.9 7.1e-38 129.4 1.9 1.8 1 0 0 1 1 1 1 C-terminal domain of RIG-I RIG-I_C PF18119.1 KFO97529.1 - 1e-31 109.8 2.0 1e-31 109.8 2.0 2.3 2 0 0 2 2 2 1 RIG-I receptor C-terminal domain Helicase_C PF00271.31 KFO97529.1 - 9.5e-20 71.0 0.1 4.3e-19 68.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFO97529.1 - 8.7e-10 38.9 0.2 2.7e-09 37.3 0.2 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFO97529.1 - 1.2e-06 28.5 0.8 3.6e-06 26.9 0.2 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 KFO97529.1 - 0.0028 16.4 2.0 0.0048 15.7 0.1 2.1 2 1 0 2 2 2 1 SNF2 family N-terminal domain PSD4 PF07631.11 KFO97529.1 - 0.0035 17.9 0.5 0.017 15.6 0.1 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1592) DUF3666 PF12408.8 KFO97529.1 - 0.054 12.7 0.2 0.16 11.2 0.2 1.8 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase Nuf2 PF03800.14 KFO97529.1 - 0.061 13.5 4.5 0.23 11.6 0.1 3.2 4 0 0 4 4 4 0 Nuf2 family AlaDh_PNT_C PF01262.21 KFO97529.1 - 0.097 12.0 0.1 0.21 10.9 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TINF2_N PF14973.6 KFO97529.1 - 0.2 12.0 3.6 0.15 12.4 1.0 2.1 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus PCAF_N PF06466.11 KFO97530.1 - 2.2e-104 348.5 2.1 3.4e-104 347.8 2.1 1.3 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain PF00439.25 KFO97530.1 - 4.7e-24 84.3 0.6 1.1e-23 83.0 0.6 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KFO97530.1 - 3.3e-10 40.2 0.1 8.4e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFO97530.1 - 1.2e-07 31.7 0.0 2.4e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFO97530.1 - 6.4e-06 26.5 0.2 1.5e-05 25.3 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Chalcone_N PF18232.1 KFO97530.1 - 0.03 14.7 0.8 8.4 6.9 0.2 2.6 2 0 0 2 2 2 0 Chalcone isomerase N-terminal domain Ras PF00071.22 KFO97531.1 - 1.3e-52 177.7 0.3 1.7e-52 177.3 0.3 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO97531.1 - 8.5e-31 106.7 0.0 1.6e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO97531.1 - 3.5e-07 29.8 0.0 5.2e-07 29.3 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFO97531.1 - 0.001 19.1 0.0 0.0014 18.7 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFO97531.1 - 0.0012 18.7 0.4 0.35 10.8 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KFO97531.1 - 0.0082 15.5 0.0 0.028 13.8 0.0 1.7 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KFO97531.1 - 0.021 15.2 0.1 0.035 14.5 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain Ion_trans PF00520.31 KFO97532.1 - 5.8e-31 107.6 13.1 8.2e-31 107.1 13.1 1.2 1 0 0 1 1 1 1 Ion transport protein PAS_9 PF13426.7 KFO97532.1 - 3.6e-20 72.2 0.1 1.1e-19 70.7 0.0 1.8 2 0 0 2 2 2 1 PAS domain Ion_trans_2 PF07885.16 KFO97532.1 - 3.3e-10 39.8 0.6 3.3e-10 39.8 0.6 3.1 4 0 0 4 4 4 1 Ion channel cNMP_binding PF00027.29 KFO97532.1 - 5.5e-09 36.0 0.0 1.2e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PAS_3 PF08447.12 KFO97532.1 - 2.2e-07 31.1 0.0 5.4e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KFO97532.1 - 6.3e-07 29.6 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 KFO97532.1 - 5.8e-06 26.3 0.0 1.3e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 PAS fold NicO PF03824.16 KFO97532.1 - 3.6 6.9 10.6 0.67 9.2 0.7 2.6 3 0 0 3 3 3 0 High-affinity nickel-transport protein Orexin PF02072.15 KFO97533.1 - 1.8e-46 157.2 5.1 2e-46 157.1 5.1 1.0 1 0 0 1 1 1 1 Prepro-orexin TAXi_N PF14543.6 KFO97533.1 - 0.28 11.4 2.4 0.46 10.7 2.2 1.4 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal PI-PLC-X PF00388.19 KFO97534.1 - 1.3e-42 144.8 0.0 2.2e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFO97534.1 - 3.4e-38 130.5 0.0 6.7e-38 129.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain PH_12 PF16457.5 KFO97534.1 - 4.5e-20 72.5 0.0 8.5e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain EF-hand_like PF09279.11 KFO97534.1 - 1.1e-16 61.1 0.0 2.3e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 KFO97534.1 - 2.9e-14 53.2 0.0 6.4e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain PH PF00169.29 KFO97534.1 - 3e-06 27.7 0.0 6.2e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_14 PF17787.1 KFO97534.1 - 0.0002 21.3 0.0 0.00039 20.3 0.0 1.4 1 0 0 1 1 1 1 PH domain Mcp5_PH PF12814.7 KFO97534.1 - 0.03 14.5 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology EF-hand_9 PF14658.6 KFO97534.1 - 0.13 12.6 0.0 0.38 11.1 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain STAT_bind PF02864.15 KFO97535.1 - 1.3e-53 181.1 1.4 2.1e-53 180.4 1.4 1.3 1 0 0 1 1 1 1 STAT protein, DNA binding domain SH2 PF00017.24 KFO97535.1 - 4.4e-12 45.9 0.0 2.3e-11 43.6 0.0 2.3 2 0 0 2 2 2 1 SH2 domain ACAS_N PF16177.5 KFO97535.1 - 0.027 14.4 0.2 8.6 6.4 0.7 2.6 2 0 0 2 2 2 0 Acetyl-coenzyme A synthetase N-terminus Big_4 PF07532.11 KFO97535.1 - 0.16 11.7 0.1 0.54 10.0 0.1 1.9 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 4) STAT_alpha PF01017.20 KFO97536.1 - 1.3e-53 181.4 16.2 2.7e-53 180.4 16.2 1.5 1 0 0 1 1 1 1 STAT protein, all-alpha domain STAT_bind PF02864.15 KFO97536.1 - 4.6e-38 130.8 1.9 8.8e-38 129.9 0.0 2.2 2 0 0 2 2 2 1 STAT protein, DNA binding domain STAT_int PF02865.17 KFO97536.1 - 5.1e-38 130.3 7.9 5.1e-38 130.3 7.9 3.2 3 1 1 4 4 4 1 STAT protein, protein interaction domain SH2 PF00017.24 KFO97536.1 - 3.2e-14 52.8 0.0 8.6e-14 51.4 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Syntaxin-6_N PF09177.11 KFO97536.1 - 0.18 12.4 4.7 0.18 12.4 1.3 2.6 2 1 1 3 3 3 0 Syntaxin 6, N-terminal YojJ PF10372.9 KFO97536.1 - 0.25 11.4 6.7 1.6 8.9 0.3 2.8 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Fib_alpha PF08702.10 KFO97536.1 - 0.29 11.3 10.3 0.27 11.4 5.3 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.7 KFO97536.1 - 0.62 10.2 8.3 0.094 12.9 3.1 2.0 2 0 0 2 2 2 0 Tropomyosin like RecG_N PF17190.4 KFO97536.1 - 1 10.1 10.1 2.1 9.2 0.2 3.8 3 1 0 3 3 3 0 RecG N-terminal helical domain MerR-DNA-bind PF09278.11 KFO97536.1 - 2.9 8.5 13.7 3.6 8.2 0.6 3.9 4 0 0 4 4 4 0 MerR, DNA binding Cep57_CLD PF14073.6 KFO97536.1 - 3.4 7.6 16.2 6.2 6.8 4.5 3.1 2 1 0 3 3 3 0 Centrosome localisation domain of Cep57 PRKG1_interact PF15898.5 KFO97536.1 - 3.5 8.6 11.3 0.95 10.4 5.2 2.6 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain eIF3_N PF09440.10 KFO97536.1 - 3.8 8.0 11.8 2.7 8.5 2.7 3.1 2 1 1 3 3 3 0 eIF3 subunit 6 N terminal domain V_ATPase_I PF01496.19 KFO97537.1 - 0 1075.0 0.0 0 1074.5 0.0 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family NAGLU PF05089.12 KFO97538.1 - 7.7e-112 373.5 0.0 1e-111 373.2 0.0 1.1 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 KFO97538.1 - 2e-83 280.0 0.0 2.6e-83 279.6 0.0 1.1 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain adh_short PF00106.25 KFO97539.1 - 6.5e-41 140.0 0.0 7.2e-41 139.8 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFO97539.1 - 1.6e-28 99.8 0.0 1.9e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFO97539.1 - 2.7e-08 33.9 0.0 3.2e-08 33.7 0.0 1.0 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFO97539.1 - 5.3e-05 22.7 0.0 7.5e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KFO97539.1 - 0.008 16.1 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Eno-Rase_NADH_b PF12242.8 KFO97539.1 - 0.035 13.9 0.2 0.068 12.9 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HLH PF00010.26 KFO97540.1 - 2.7e-15 56.0 0.1 7.8e-15 54.6 0.1 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF3322 PF11795.8 KFO97540.1 - 0.029 14.4 0.1 0.099 12.6 0.2 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) RNA_pol_Rpb4 PF03874.16 KFO97540.1 - 0.55 10.6 5.1 0.99 9.7 4.7 1.8 1 1 0 1 1 1 0 RNA polymerase Rpb4 LZ3wCH PF18517.1 KFO97541.1 - 8.7e-15 54.6 0.1 2.3e-14 53.2 0.0 1.7 2 0 0 2 2 2 1 Leucine zipper with capping helix domain FapA PF03961.13 KFO97541.1 - 0.00012 20.8 0.2 0.00014 20.7 0.2 1.0 1 0 0 1 1 1 1 Flagellar Assembly Protein A Tubulin PF00091.25 KFO97543.1 - 5.4e-51 173.6 0.0 8.7e-51 172.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFO97543.1 - 8.2e-47 158.5 0.1 1.7e-46 157.5 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFO97543.1 - 0.023 14.4 0.2 0.057 13.1 0.0 1.7 2 0 0 2 2 2 0 Tubulin domain Tubulin_2 PF13809.6 KFO97543.1 - 0.046 12.9 0.0 0.078 12.2 0.0 1.4 1 0 0 1 1 1 0 Tubulin like MyTH4 PF00784.17 KFO97545.1 - 2.9e-26 92.1 0.0 6.5e-26 90.9 0.0 1.6 1 0 0 1 1 1 1 MyTH4 domain RA PF00788.23 KFO97545.1 - 5e-07 30.3 0.0 1.2e-06 29.1 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PH PF00169.29 KFO97545.1 - 3.5e-05 24.2 0.1 5.8e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 PH domain ssDNA_DBD PF18333.1 KFO97545.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Non-canonical single-stranded DNA-binding domain F5_F8_type_C PF00754.25 KFO97546.1 - 3.9e-10 39.9 0.8 4.1e-10 39.9 0.8 1.0 1 0 0 1 1 1 1 F5/8 type C domain SCAB-Ig PF16709.5 KFO97546.1 - 0.13 12.4 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Ig domain of plant-specific actin-binding protein Laminin_G_2 PF02210.24 KFO97547.1 - 4.7e-17 62.8 1.5 3.1e-15 56.9 0.4 2.1 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 KFO97547.1 - 8.3e-14 51.9 0.0 9.1e-12 45.3 0.0 2.2 2 0 0 2 2 2 2 Laminin G domain Laminin_G_2 PF02210.24 KFO97548.1 - 1.6e-52 177.4 0.0 5.7e-19 68.9 0.0 3.3 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.23 KFO97548.1 - 8.9e-35 119.8 0.0 7.5e-11 42.4 0.0 3.3 3 0 0 3 3 3 3 Laminin G domain EGF PF00008.27 KFO97548.1 - 2.3e-05 24.6 3.1 2.3e-05 24.6 3.1 3.7 3 0 0 3 3 3 2 EGF-like domain Laminin_G_3 PF13385.6 KFO97548.1 - 0.00023 21.3 0.0 0.0012 19.0 0.0 2.1 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Fibrinogen_C PF00147.18 KFO97548.1 - 0.00051 19.9 0.0 0.00084 19.2 0.0 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain hEGF PF12661.7 KFO97548.1 - 0.5 11.1 20.4 0.18 12.5 0.4 3.9 3 0 0 3 3 3 0 Human growth factor-like EGF PRC2_HTH_1 PF18118.1 KFO97549.1 - 6.4e-29 100.7 1.0 6.4e-29 100.7 1.0 2.2 3 0 0 3 3 3 1 Polycomb repressive complex 2 tri-helical domain SET PF00856.28 KFO97549.1 - 2.6e-18 67.0 0.5 2e-17 64.1 0.3 2.6 2 1 0 2 2 2 1 SET domain EZH2_WD-Binding PF11616.8 KFO97549.1 - 6.6e-17 61.3 0.2 1.5e-16 60.1 0.2 1.7 1 0 0 1 1 1 1 WD repeat binding protein EZH2 preSET_CXC PF18264.1 KFO97549.1 - 7.7e-12 45.5 15.7 7.7e-12 45.5 15.7 4.3 3 1 0 3 3 3 1 CXC domain PIN PF01850.21 KFO97549.1 - 0.058 13.9 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 PIN domain ESCRT-II PF05871.12 KFO97550.1 - 1.7e-28 99.6 0.1 2.5e-28 99.1 0.1 1.3 1 0 0 1 1 1 1 ESCRT-II complex subunit Cyclin_N PF00134.23 KFO97551.1 - 6.7e-08 32.3 0.4 0.00097 18.9 0.1 2.6 2 0 0 2 2 2 2 Cyclin, N-terminal domain MazG-like PF12643.7 KFO97551.1 - 0.019 15.2 0.6 0.13 12.6 0.6 2.3 1 1 0 1 1 1 0 MazG-like family APG6 PF04111.12 KFO97552.1 - 9.1e-77 257.1 0.0 1.5e-76 256.4 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KFO97552.1 - 2.2e-29 102.7 33.2 3.7e-29 101.9 33.2 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region BH3 PF15285.6 KFO97552.1 - 3.9e-17 61.6 0.2 6.4e-17 60.9 0.2 1.4 1 0 0 1 1 1 1 Beclin-1 BH3 domain, Bcl-2-interacting FapA PF03961.13 KFO97552.1 - 0.0048 15.6 10.0 0.0074 15.0 10.0 1.3 1 0 0 1 1 1 1 Flagellar Assembly Protein A IFT57 PF10498.9 KFO97552.1 - 0.063 12.2 16.5 0.11 11.5 16.5 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Exonuc_VII_L PF02601.15 KFO97552.1 - 0.14 11.7 5.6 0.2 11.2 5.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit MT PF12777.7 KFO97552.1 - 0.38 9.7 8.7 0.7 8.9 8.7 1.4 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor LMBR1 PF04791.16 KFO97552.1 - 0.41 9.5 1.8 0.56 9.1 1.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein ERM PF00769.19 KFO97552.1 - 0.63 9.8 21.9 1.1 9.0 21.9 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family V_ATPase_I PF01496.19 KFO97552.1 - 1.3 6.8 9.6 1.7 6.5 9.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Jnk-SapK_ap_N PF09744.9 KFO97552.1 - 1.4 9.1 22.1 2.9 8.1 22.1 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 TMPIT PF07851.13 KFO97552.1 - 2.4 7.3 10.3 4.4 6.5 10.3 1.5 1 0 0 1 1 1 0 TMPIT-like protein Golgin_A5 PF09787.9 KFO97552.1 - 3.8 6.9 19.9 7.1 6.0 19.9 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 YabA PF06156.13 KFO97552.1 - 4.2 8.1 15.2 1.4 9.6 9.8 2.4 1 1 1 2 2 2 0 Initiation control protein YabA UPF0242 PF06785.11 KFO97552.1 - 7.8 6.5 20.6 14 5.7 20.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GAS PF13851.6 KFO97552.1 - 9.3 5.5 26.7 0.54 9.6 10.3 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding PA28_beta PF02252.18 KFO97553.1 - 4.8e-65 217.6 3.4 6.2e-65 217.3 3.4 1.1 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 KFO97553.1 - 3.8e-24 84.5 0.6 8.8e-24 83.3 0.6 1.7 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit TMF_TATA_bd PF12325.8 KFO97553.1 - 0.12 12.6 1.7 0.2 11.9 0.3 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Cu_amine_oxid PF01179.20 KFO97554.1 - 4.4e-123 411.2 0.2 5.9e-123 410.8 0.2 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KFO97554.1 - 5.1e-16 58.9 0.0 9.7e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KFO97554.1 - 1.2e-12 47.9 0.0 2.4e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF1965 PF09248.10 KFO97554.1 - 3.8e-06 26.6 0.6 3.3e-05 23.6 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF1965) Cu_amine_oxid PF01179.20 KFO97555.1 - 7.8e-125 417.0 0.0 1e-124 416.6 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KFO97555.1 - 6.3e-17 61.8 0.0 1.1e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KFO97555.1 - 2.4e-13 50.1 0.0 4.9e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF1965 PF09248.10 KFO97555.1 - 0.028 14.2 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) bMG6 PF17962.1 KFO97555.1 - 0.069 13.3 0.1 0.42 10.8 0.0 2.1 2 1 0 2 2 2 0 Bacterial macroglobulin domain 6 PAP2 PF01569.21 KFO97556.1 - 6.5e-17 61.6 7.0 6.5e-17 61.6 7.0 1.8 1 1 0 1 1 1 1 PAP2 superfamily Sulfate_transp PF00916.20 KFO97556.1 - 0.0004 19.3 1.7 0.00062 18.6 1.7 1.3 1 0 0 1 1 1 1 Sulfate permease family tRNA_SAD PF07973.14 KFO97557.1 - 1.4e-09 37.9 0.2 3.1e-09 36.8 0.2 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Nod_GRP PF07806.11 KFO97557.1 - 0.12 12.2 2.3 0.27 11.1 2.3 1.5 1 0 0 1 1 1 0 Nodule-specific GRP repeat RUN PF02759.19 KFO97558.1 - 4.1e-35 120.7 0.1 6.9e-35 120.0 0.1 1.4 1 0 0 1 1 1 1 RUN domain Ribosomal_L27e PF01777.18 KFO97560.1 - 2e-39 133.8 8.8 2.3e-39 133.6 8.8 1.0 1 0 0 1 1 1 1 Ribosomal L27e protein family NID PF07292.13 KFO97561.1 - 5.3e-55 184.0 0.0 4.5e-26 91.3 0.0 2.2 2 0 0 2 2 2 2 Nmi/IFP 35 domain (NID) PHM7_cyt PF14703.6 KFO97561.1 - 0.076 13.2 0.0 1.2 9.4 0.0 2.4 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Ras PF00071.22 KFO97562.1 - 4.8e-19 68.5 0.0 7.9e-19 67.8 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFO97562.1 - 3.2e-05 24.1 0.0 6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase OB_NTP_bind PF07717.16 KFO97563.1 - 3.3e-26 91.5 0.0 6.8e-26 90.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KFO97563.1 - 2.5e-25 88.9 0.1 4.6e-25 88.0 0.1 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFO97563.1 - 6e-14 52.3 0.0 1.5e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFO97563.1 - 4.7e-05 23.2 0.1 0.00021 21.1 0.2 2.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFO97563.1 - 0.0056 17.0 1.1 0.032 14.5 0.9 2.3 2 1 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 KFO97563.1 - 0.028 14.4 0.1 0.06 13.3 0.1 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 KFO97563.1 - 0.057 13.3 0.0 0.84 9.5 0.0 2.6 2 1 1 3 3 3 0 Helicase AAA_19 PF13245.6 KFO97563.1 - 0.13 12.6 0.1 0.31 11.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain ETS_PEA3_N PF04621.13 KFO97564.1 - 1.2e-98 331.2 25.4 1.5e-97 327.6 25.4 2.0 1 1 0 1 1 1 1 PEA3 subfamily ETS-domain transcription factor N terminal domain Ets PF00178.22 KFO97564.1 - 8e-39 132.0 0.1 1.3e-38 131.3 0.1 1.3 1 0 0 1 1 1 1 Ets-domain Homeodomain PF00046.29 KFO97565.1 - 8.6e-24 83.1 8.0 1.1e-23 82.9 8.0 1.1 1 0 0 1 1 1 1 Homeodomain Alpha-2-MRAP_C PF06401.11 KFO97565.1 - 0.026 14.5 1.5 0.035 14.1 1.4 1.3 1 1 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain Homeobox_KN PF05920.11 KFO97565.1 - 0.051 13.5 0.7 0.12 12.3 0.1 1.8 2 0 0 2 2 2 0 Homeobox KN domain GAIN_A PF18619.1 KFO97565.1 - 0.11 12.7 0.4 0.18 12.0 0.4 1.3 1 0 0 1 1 1 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Sclerostin PF05463.11 KFO97566.1 - 2.1e-72 243.1 6.9 2.3e-72 242.9 6.9 1.0 1 0 0 1 1 1 1 Sclerostin (SOST) DAN PF03045.15 KFO97566.1 - 4.2e-25 88.0 3.4 5.6e-25 87.6 3.4 1.2 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.22 KFO97566.1 - 1.3e-05 25.5 2.1 2.1e-05 24.8 2.1 1.3 1 0 0 1 1 1 1 Cystine-knot domain DSPc PF00782.20 KFO97567.1 - 1e-34 119.2 0.1 1.2e-34 118.9 0.1 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFO97567.1 - 0.00011 21.8 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KFO97567.1 - 0.00041 20.6 0.0 0.00053 20.3 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 KFO97567.1 - 0.0019 18.3 0.0 0.0025 18.0 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate baeRF_family7 PF18849.1 KFO97567.1 - 0.018 15.2 0.1 0.025 14.8 0.1 1.2 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 7 DUF442 PF04273.13 KFO97567.1 - 0.041 14.0 0.0 0.085 12.9 0.0 1.7 1 1 0 1 1 1 0 Putative phosphatase (DUF442) APG12 PF04110.13 KFO97567.1 - 0.081 13.3 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 baeRF_family6 PF18848.1 KFO97567.1 - 0.11 12.9 0.1 0.15 12.4 0.1 1.2 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 6 RimK PF08443.11 KFO97567.1 - 0.13 11.8 0.0 5.5 6.6 0.0 2.1 1 1 1 2 2 2 0 RimK-like ATP-grasp domain Ras PF00071.22 KFO97568.1 - 2.6e-55 186.5 0.1 4.5e-55 185.7 0.0 1.4 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KFO97568.1 - 3e-33 114.6 0.0 4.7e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO97568.1 - 4.2e-17 62.2 0.1 5.1e-17 61.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFO97568.1 - 8.9e-06 25.8 0.0 0.00031 20.8 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFO97568.1 - 0.00014 21.3 0.0 0.00023 20.6 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFO97568.1 - 0.0014 18.3 0.0 0.004 16.7 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFO97568.1 - 0.031 14.2 0.4 4.7 7.1 0.1 2.4 2 1 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 KFO97568.1 - 0.045 13.2 0.0 0.081 12.3 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 KFO97568.1 - 0.054 13.3 0.1 0.11 12.2 0.0 1.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Guanylate_kin PF00625.21 KFO97569.1 - 9e-42 142.8 1.1 1.6e-41 142.0 1.1 1.4 1 0 0 1 1 1 1 Guanylate kinase L27 PF02828.16 KFO97569.1 - 1.2e-24 85.8 3.6 5.2e-13 48.5 0.5 2.8 2 0 0 2 2 2 2 L27 domain PDZ PF00595.24 KFO97569.1 - 2.2e-11 43.9 1.0 5.3e-11 42.7 1.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFO97569.1 - 8.7e-09 35.1 0.7 2.4e-08 33.7 0.3 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KFO97569.1 - 1.5e-05 25.2 0.1 6.2e-05 23.3 0.1 2.0 1 0 0 1 1 1 1 PDZ domain SH3_2 PF07653.17 KFO97569.1 - 0.0058 16.3 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFO97569.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 SH3 domain NPBW PF15180.6 KFO97569.1 - 0.015 15.1 0.2 6.3 6.7 0.0 3.0 3 0 0 3 3 3 0 Neuropeptides B and W DUF4186 PF13811.6 KFO97569.1 - 0.15 12.1 0.1 0.45 10.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4186) Cytochrom_B561 PF03188.16 KFO97570.1 - 1.8e-42 144.7 8.8 1.8e-42 144.7 8.8 1.8 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 Claudin_2 PF13903.6 KFO97570.1 - 0.037 13.8 0.1 0.037 13.8 0.1 2.2 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Ank_2 PF12796.7 KFO97571.1 - 6.3e-67 222.2 1.6 1.4e-13 51.3 0.0 5.9 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFO97571.1 - 4e-47 158.0 1.2 2.7e-09 37.4 0.0 7.3 3 3 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFO97571.1 - 2.6e-37 122.6 0.4 0.0045 17.4 0.0 10.8 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 KFO97571.1 - 6.1e-35 118.8 4.3 1.9e-08 34.4 0.1 9.0 3 2 7 10 10 10 9 Ankyrin repeats (many copies) Ank PF00023.30 KFO97571.1 - 5.7e-33 111.9 6.8 0.00041 20.7 0.0 10.9 11 0 0 11 11 11 5 Ankyrin repeat TPR_2 PF07719.17 KFO97571.1 - 4.7e-11 41.9 6.8 0.0011 18.9 1.3 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFO97571.1 - 4.7e-09 35.8 5.2 0.016 14.9 0.1 3.4 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.28 KFO97571.1 - 1.1e-07 31.3 8.2 0.00051 19.7 1.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFO97571.1 - 1.9e-07 30.7 1.1 0.022 14.9 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFO97571.1 - 2.2e-06 27.7 0.2 2.4e-05 24.4 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFO97571.1 - 2.8e-05 24.6 1.3 0.00011 22.8 0.5 2.6 2 1 0 2 2 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFO97571.1 - 0.00054 20.4 2.9 0.0096 16.4 0.7 2.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFO97571.1 - 0.00059 20.1 2.9 0.044 14.1 0.1 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat AAA_16 PF13191.6 KFO97571.1 - 0.0031 17.9 3.5 0.0036 17.7 0.0 2.8 4 0 0 4 4 3 1 AAA ATPase domain TPR_16 PF13432.6 KFO97571.1 - 0.0046 17.6 3.3 1 10.1 0.1 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFO97571.1 - 0.053 13.6 0.3 0.86 9.8 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFO97571.1 - 0.075 13.4 2.3 0.42 11.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat SUIM_assoc PF16619.5 KFO97571.1 - 0.097 12.8 9.2 0.059 13.4 5.5 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Drf_FH3 PF06367.16 KFO97571.1 - 0.96 9.0 4.6 0.11 12.1 0.1 1.6 2 0 0 2 2 1 0 Diaphanous FH3 Domain TPR_6 PF13174.6 KFO97571.1 - 1.4 9.7 6.0 19 6.2 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_23 PF13489.6 KFO97573.1 - 1.4e-15 57.5 0.0 2.2e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFO97573.1 - 3.1e-14 53.5 0.0 5.9e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFO97573.1 - 3.7e-13 50.0 0.0 9.2e-13 48.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFO97573.1 - 2.1e-10 41.1 0.0 3.9e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFO97573.1 - 1.3e-08 34.8 0.1 2.5e-08 33.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KFO97573.1 - 0.0024 17.4 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.18 KFO97573.1 - 0.046 13.2 0.0 1.2 8.5 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain TPMT PF05724.11 KFO97573.1 - 0.047 13.4 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Integrin_beta PF00362.18 KFO97574.1 - 1.3e-110 368.9 0.0 1.9e-110 368.4 0.0 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_B_tail PF07965.12 KFO97574.1 - 9.8e-22 77.2 9.0 9.8e-22 77.2 9.0 4.9 3 1 2 5 5 5 1 Integrin beta tail domain I-EGF_1 PF18372.1 KFO97574.1 - 1.9e-11 43.9 12.0 1.9e-11 43.9 12.0 6.3 7 0 0 7 7 7 4 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 KFO97574.1 - 3.5e-11 43.3 101.2 1.5e-05 25.2 15.9 6.5 5 2 1 6 6 6 4 EGF-like domain Integrin_b_cyt PF08725.11 KFO97574.1 - 7.7e-09 35.1 0.9 7.7e-09 35.1 0.9 2.3 3 0 0 3 3 3 1 Integrin beta cytoplasmic domain Tmemb_9 PF05434.11 KFO97575.1 - 0.0043 16.9 0.3 0.0052 16.7 0.3 1.1 1 0 0 1 1 1 1 TMEM9 DUF1072 PF06380.11 KFO97575.1 - 0.15 12.0 7.5 0.33 10.9 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) 7tm_2 PF00002.24 KFO97576.1 - 1.2e-75 253.9 21.8 1.5e-75 253.6 21.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFO97576.1 - 4.7e-17 62.0 1.8 1e-16 61.0 1.8 1.6 1 0 0 1 1 1 1 Hormone receptor domain DUF4574 PF15141.6 KFO97576.1 - 2.9 7.9 4.3 19 5.2 0.1 2.6 2 1 1 3 3 3 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 zf-H2C2_2 PF13465.6 KFO97577.1 - 4.7e-61 200.7 55.6 9.5e-10 38.5 0.4 8.3 8 0 0 8 8 8 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFO97577.1 - 1.3e-38 129.3 65.2 1.2e-05 25.5 0.8 8.2 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO97577.1 - 1.4e-28 97.1 60.0 0.00035 21.2 0.7 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO97577.1 - 8e-23 80.2 20.2 0.0014 18.8 0.0 8.1 7 1 1 8 8 8 6 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFO97577.1 - 2.5e-21 75.1 46.4 2.3e-06 27.2 0.5 8.1 8 0 0 8 8 8 6 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KFO97577.1 - 9.1e-13 48.1 30.5 0.00066 19.7 3.2 6.3 4 2 2 6 6 6 6 Zinc ribbon domain XPA_N PF01286.18 KFO97577.1 - 3.4e-09 36.6 29.1 1.6 8.9 0.1 8.0 8 0 0 8 8 8 3 XPA protein N-terminal zf_UBZ PF18439.1 KFO97577.1 - 6e-09 35.3 30.3 0.049 13.2 0.2 8.0 8 0 0 8 8 8 3 Ubiquitin-Binding Zinc Finger zf-LYAR PF08790.11 KFO97577.1 - 7e-09 35.4 27.4 0.072 13.0 0.2 8.1 8 0 0 8 8 8 3 LYAR-type C2HC zinc finger zinc_ribbon_9 PF14369.6 KFO97577.1 - 7.8e-09 35.7 20.9 0.076 13.3 0.1 7.6 8 0 0 8 8 8 2 zinc-ribbon zf-C2H2_6 PF13912.6 KFO97577.1 - 6.6e-07 29.2 62.5 0.071 13.1 2.0 9.5 8 2 0 8 8 8 4 C2H2-type zinc finger HypA PF01155.19 KFO97577.1 - 1.3e-05 25.2 17.0 0.26 11.3 0.5 4.5 1 1 2 3 3 3 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KFO97577.1 - 1.3e-05 25.1 22.2 1.8e+04 -4.6 22.2 4.9 1 1 0 1 1 0 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 KFO97577.1 - 5.8e-05 23.8 17.1 1.4 9.8 1.5 4.5 1 1 3 4 4 4 3 zinc-ribbon family zf-trcl PF13451.6 KFO97577.1 - 7.5e-05 22.6 23.9 5.9 6.9 0.0 7.5 7 1 0 7 7 7 0 Probable zinc-ribbon domain Zn_ribbon_SprT PF17283.2 KFO97577.1 - 9.3e-05 22.3 38.8 0.17 11.8 2.7 7.2 3 3 2 5 5 5 3 SprT-like zinc ribbon domain zf-met PF12874.7 KFO97577.1 - 0.00018 21.8 34.7 0.037 14.4 0.3 7.1 7 0 0 7 7 7 3 Zinc-finger of C2H2 type FYDLN_acid PF09538.10 KFO97577.1 - 0.00021 21.9 9.8 14 6.4 0.5 6.7 2 1 4 6 6 6 0 Protein of unknown function (FYDLN_acid) zf-C2H2_2 PF12756.7 KFO97577.1 - 0.00025 21.3 32.8 2 8.8 0.2 7.5 1 1 6 7 7 7 2 C2H2 type zinc-finger (2 copies) DUF2256 PF10013.9 KFO97577.1 - 0.00073 19.6 19.4 11 6.2 0.0 7.8 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) TFIIS_C PF01096.18 KFO97577.1 - 0.00084 19.1 28.9 8.6 6.3 0.1 7.9 8 0 0 8 8 8 0 Transcription factor S-II (TFIIS) zf-Di19 PF05605.12 KFO97577.1 - 0.0011 19.2 29.8 0.3 11.4 1.4 5.7 1 1 5 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding zf-HIT PF04438.16 KFO97577.1 - 0.01 15.7 32.0 2.8 7.9 0.3 7.7 8 0 0 8 8 8 0 HIT zinc finger zf-C2HE PF16278.5 KFO97577.1 - 0.012 16.1 45.2 0.017 15.5 1.8 8.0 1 1 7 8 8 8 0 C2HE / C2H2 / C2HC zinc-binding finger YhfH PF14149.6 KFO97577.1 - 0.016 15.1 26.7 5.7 7.0 0.2 7.7 8 0 0 8 8 8 0 YhfH-like protein DUF2180 PF09947.9 KFO97577.1 - 0.056 13.4 16.1 2.7 8.0 0.1 5.3 1 1 3 5 5 5 0 Uncharacterized protein conserved in archaea (DUF2180) HalOD2 PF18547.1 KFO97577.1 - 0.092 12.7 27.1 2.3 8.2 1.2 6.2 4 2 1 6 6 6 0 Halobacterial output domain 2 TerY_C PF15616.6 KFO97577.1 - 0.3 11.2 9.1 4.1 7.5 0.1 3.4 1 1 1 3 3 3 0 TerY-C metal binding domain zf-RING_7 PF02591.15 KFO97577.1 - 0.37 11.0 16.9 5.9 7.2 0.1 5.5 6 0 0 6 6 5 0 C4-type zinc ribbon domain GAGA PF09237.11 KFO97577.1 - 0.67 9.8 10.8 4 7.3 0.1 3.9 4 0 0 4 4 4 0 GAGA factor BolA PF01722.18 KFO97577.1 - 0.74 10.1 8.5 29 5.0 2.7 3.5 2 1 0 2 2 2 0 BolA-like protein zf_C2H2_13 PF18508.1 KFO97577.1 - 0.8 9.3 0.1 0.8 9.3 0.1 6.6 8 0 0 8 8 8 0 Zinc finger domain YacG PF03884.14 KFO97577.1 - 1 9.1 6.8 18 5.1 0.1 4.3 5 0 0 5 5 5 0 DNA gyrase inhibitor YacG zf-C2H2_3rep PF18868.1 KFO97577.1 - 1.2 9.8 22.8 14 6.4 3.4 6.0 1 1 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats Ta0938 PF11494.8 KFO97577.1 - 2.9 8.2 4.3 9 6.6 0.1 3.2 1 1 3 4 4 4 0 Ta0938 Zn-C2H2_12 PF18112.1 KFO97577.1 - 3.1 8.3 14.7 14 6.2 0.3 5.6 6 0 0 6 6 6 0 Autophagy receptor zinc finger-C2H2 domain DUF3268 PF11672.8 KFO97577.1 - 4.6 7.6 16.2 6.1 7.2 0.5 4.0 2 2 3 5 5 5 0 zinc-finger-containing domain LIM PF00412.22 KFO97577.1 - 5.1 7.4 27.0 5.9 7.2 1.0 6.2 1 1 5 7 7 6 0 LIM domain DNA_RNApol_7kD PF03604.13 KFO97577.1 - 6.6 6.5 29.1 20 4.9 0.2 7.6 8 0 0 8 8 8 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_9 PF16293.5 KFO97577.1 - 8.2 6.4 12.4 11 5.9 0.5 4.6 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) DUF2039 PF10217.9 KFO97577.1 - 8.7 6.8 15.5 0.73 10.2 0.1 4.0 1 1 4 5 5 5 0 Uncharacterized conserved protein (DUF2039) zf-C2H2 PF00096.26 KFO97578.1 - 3e-11 43.1 8.5 1.5e-05 25.2 0.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO97578.1 - 2.4e-08 34.0 7.8 7e-07 29.4 2.1 2.3 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFO97578.1 - 2.1e-05 25.0 8.5 0.013 16.3 1.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf_UBZ PF18439.1 KFO97578.1 - 0.0017 17.9 2.5 0.58 9.8 0.3 2.1 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 KFO97578.1 - 0.0046 17.2 0.5 0.58 10.5 0.2 2.3 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFO97578.1 - 0.005 17.1 4.4 0.081 13.2 0.4 2.1 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_9 PF14369.6 KFO97578.1 - 0.018 15.3 7.1 0.39 11.0 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon Zn-ribbon_8 PF09723.10 KFO97578.1 - 0.022 14.9 2.5 0.064 13.4 2.5 1.8 1 1 0 1 1 1 0 Zinc ribbon domain FYDLN_acid PF09538.10 KFO97578.1 - 0.027 15.2 0.6 0.052 14.2 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-C2H2_6 PF13912.6 KFO97578.1 - 0.033 14.2 7.0 0.2 11.7 0.6 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Prok-RING_1 PF14446.6 KFO97578.1 - 0.051 13.5 1.8 1.8 8.6 0.3 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-LYAR PF08790.11 KFO97578.1 - 0.12 12.4 3.4 5.4 7.0 0.4 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Cys_rich_CPXG PF14255.6 KFO97578.1 - 0.13 12.2 2.7 0.51 10.3 0.1 2.2 2 0 0 2 2 2 0 Cysteine-rich CPXCG CpXC PF14353.6 KFO97578.1 - 0.21 11.6 1.8 11 6.1 0.2 2.0 1 1 1 2 2 2 0 CpXC protein zf-C2H2_9 PF16293.5 KFO97578.1 - 0.32 10.9 2.4 2 8.3 0.2 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) OrfB_Zn_ribbon PF07282.11 KFO97578.1 - 0.63 10.0 3.1 3.6 7.6 3.1 2.0 1 1 0 1 1 1 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.7 KFO97578.1 - 1 9.4 6.8 6.2 6.9 7.2 1.9 1 1 1 2 2 2 0 Transposase zinc-ribbon domain DUF35_N PF12172.8 KFO97578.1 - 1.2 9.1 7.7 11 6.1 3.4 2.7 1 1 1 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_4 PF13717.6 KFO97578.1 - 8.6 6.4 7.6 6.9 6.7 0.7 2.2 2 0 0 2 2 2 0 zinc-ribbon domain 7tm_4 PF13853.6 KFO97579.1 - 1.8e-53 182.1 21.3 2.2e-53 181.8 21.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO97579.1 - 1.1e-25 90.5 23.2 1.5e-25 90.0 23.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFO97580.1 - 1.3e-48 166.1 17.4 1.6e-48 165.8 17.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO97580.1 - 1.3e-29 103.4 17.8 1.9e-29 102.8 17.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFO97580.1 - 0.014 14.8 20.9 0.064 12.6 19.1 2.1 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFO97581.1 - 5.7e-53 180.4 22.2 6.7e-53 180.2 22.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO97581.1 - 4.7e-28 98.2 21.7 6.5e-28 97.8 21.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Peptidase_M2 PF01401.18 KFO97582.1 - 0 1750.8 10.9 5.9e-273 906.7 3.8 2.0 2 0 0 2 2 2 2 Angiotensin-converting enzyme Peptidase_M32 PF02074.15 KFO97582.1 - 0.015 14.1 4.3 0.58 8.9 0.0 3.7 4 0 0 4 4 4 0 Carboxypeptidase Taq (M32) metallopeptidase Ku_PK_bind PF08785.11 KFO97582.1 - 0.099 12.8 0.0 1.5 8.9 0.1 2.4 2 0 0 2 2 2 0 Ku C terminal domain like DDR PF08841.10 KFO97582.1 - 0.15 11.1 0.1 9.2 5.1 0.0 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain GETHR PF05671.11 KFO97585.1 - 5.5e-23 80.0 69.4 0.0052 16.1 6.7 7.5 1 1 6 7 7 7 7 GETHR pentapeptide repeat (5 copies) LIM PF00412.22 KFO97586.1 - 4.9e-11 42.7 10.9 5.3e-11 42.6 10.9 1.0 1 0 0 1 1 1 1 LIM domain zf-SNAP50_C PF12251.8 KFO97586.1 - 0.32 10.6 7.7 0.35 10.5 7.7 1.1 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal zf-CCCH PF00642.24 KFO97587.1 - 5.3e-09 35.8 2.7 5.3e-09 35.8 2.7 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KFO97587.1 - 1.3e-08 34.5 9.1 2.6e-08 33.6 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFO97587.1 - 5.8e-08 32.4 10.2 1.3e-07 31.4 10.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFO97587.1 - 4.6e-06 26.4 11.2 1.1e-05 25.1 11.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFO97587.1 - 6e-06 26.1 12.9 1.3e-05 25.0 12.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFO97587.1 - 1.2e-05 25.6 10.5 2.6e-05 24.5 10.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFO97587.1 - 3.4e-05 23.8 9.9 9.6e-05 22.3 9.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf_CCCH_4 PF18345.1 KFO97587.1 - 5.7e-05 23.0 4.4 5.7e-05 23.0 4.4 2.2 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 KFO97587.1 - 0.00041 20.1 2.7 0.00041 20.1 2.7 2.6 2 0 0 2 2 2 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 KFO97587.1 - 0.00055 19.7 7.9 0.0011 18.8 7.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFO97587.1 - 0.0027 17.8 9.7 0.0027 17.8 9.7 1.8 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KFO97587.1 - 0.021 14.9 7.4 0.021 14.9 7.4 1.9 2 0 0 2 2 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 KFO97587.1 - 0.024 14.4 4.7 0.024 14.4 4.7 1.8 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.14 KFO97587.1 - 0.13 11.9 7.7 0.24 11.1 7.7 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-CCCH_2 PF14608.6 KFO97587.1 - 1 10.0 7.7 0.11 13.0 2.5 2.2 2 0 0 2 2 1 0 RNA-binding, Nab2-type zinc finger zf-rbx1 PF12678.7 KFO97587.1 - 4.4 7.7 9.2 24 5.3 9.2 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain Pkinase PF00069.25 KFO97588.1 - 1.9e-35 122.5 0.0 2.5e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO97588.1 - 1.8e-23 83.1 0.0 2.9e-22 79.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase DUF1682 PF07946.14 KFO97589.1 - 4.6e-92 308.7 4.5 4.6e-92 308.7 4.5 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1682) RR_TM4-6 PF06459.12 KFO97589.1 - 9.5 6.0 17.5 11 5.7 8.1 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 7tm_2 PF00002.24 KFO97590.1 - 1.2e-83 280.2 13.7 1.5e-83 279.9 13.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFO97590.1 - 1.4e-15 57.3 6.4 3.1e-15 56.2 6.4 1.5 1 0 0 1 1 1 1 Hormone receptor domain EF-hand_6 PF13405.6 KFO97591.1 - 1e-08 34.4 0.0 0.00091 19.0 0.0 3.5 4 1 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KFO97591.1 - 0.00014 21.1 1.3 0.11 12.1 0.0 4.1 5 1 1 6 6 6 2 EF hand EF-hand_7 PF13499.6 KFO97591.1 - 0.0033 17.9 0.0 0.053 14.0 0.0 2.4 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.6 KFO97591.1 - 0.012 15.9 0.0 0.85 10.0 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.6 KFO97591.1 - 0.38 10.6 3.3 11 6.0 0.1 3.1 2 1 1 3 3 3 0 EF-hand domain pair TPR_1 PF00515.28 KFO97592.1 - 6.7e-46 152.3 13.9 1.2e-09 37.5 0.2 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 KFO97592.1 - 6.9e-33 110.1 14.8 6.4e-06 25.9 0.1 9.6 9 0 0 9 9 9 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO97592.1 - 3.8e-32 110.3 25.6 9.9e-23 80.2 5.3 5.5 3 1 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KFO97592.1 - 5.1e-29 98.0 10.2 0.00014 21.8 0.2 9.4 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 KFO97592.1 - 6.3e-27 93.7 4.2 3.2e-07 30.5 0.0 7.1 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 KFO97592.1 - 8.6e-25 86.2 13.9 9.3e-07 28.4 0.1 8.5 4 2 5 9 9 8 5 TPR repeat TPR_17 PF13431.6 KFO97592.1 - 7.4e-23 79.2 9.0 0.0038 17.5 0.0 9.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 KFO97592.1 - 2.8e-20 72.6 5.1 0.082 13.4 0.0 7.7 5 1 3 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.6 KFO97592.1 - 4.2e-19 68.9 0.0 6e-08 33.2 0.0 6.1 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFO97592.1 - 1.5e-16 59.6 0.1 0.011 16.5 0.0 8.7 4 1 5 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFO97592.1 - 1.5e-13 50.5 9.0 0.17 12.6 0.0 8.3 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFO97592.1 - 9.6e-12 44.9 0.0 4.7e-05 23.5 0.0 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFO97592.1 - 8.7e-07 28.5 2.7 4.2 7.6 0.0 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat ChAPs PF09295.10 KFO97592.1 - 1.5e-06 27.5 1.0 0.0018 17.3 0.0 2.3 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.6 KFO97592.1 - 1.6e-05 24.2 0.0 1.1 8.4 0.0 4.5 3 1 1 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFO97592.1 - 0.00013 21.5 0.2 0.2 11.0 0.0 3.3 2 1 1 3 3 3 1 MalT-like TPR region TPR_20 PF14561.6 KFO97592.1 - 0.0072 16.6 0.5 0.14 12.5 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 KFO97592.1 - 0.014 15.1 0.0 0.31 10.7 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 KFO97592.1 - 0.022 14.6 2.9 4.9 7.2 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Cas_Cas02710 PF09670.10 KFO97592.1 - 0.033 13.0 0.1 0.11 11.2 0.0 1.9 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas02710) SRP_TPR_like PF17004.5 KFO97592.1 - 0.092 12.8 7.9 5.5 7.0 0.5 3.7 3 1 1 4 4 4 0 Putative TPR-like repeat PPTA PF01239.22 KFO97592.1 - 0.1 12.4 2.4 1.5 8.7 0.2 2.8 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat DUF2225 PF09986.9 KFO97592.1 - 2.5 7.7 7.7 1.7 8.3 0.2 3.2 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) PEHE PF15275.6 KFO97593.1 - 8.8e-15 55.5 0.6 8.8e-15 55.5 0.6 3.1 2 1 0 2 2 2 1 PEHE domain Tubulin-binding PF00418.19 KFO97594.1 - 7.7e-57 189.0 37.6 4.6e-16 58.5 1.7 5.8 6 0 0 6 6 6 5 Tau and MAP protein, tubulin-binding repeat Tmemb_cc2 PF10267.9 KFO97594.1 - 5 6.2 11.0 0.67 9.0 0.7 2.6 2 1 1 3 3 3 0 Predicted transmembrane and coiled-coil 2 protein Mito_carr PF00153.27 KFO97595.1 - 3.6e-54 180.7 0.7 6.7e-19 67.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RIIa PF02197.17 KFO97595.1 - 0.2 11.3 0.7 0.35 10.6 0.7 1.4 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit HCO3_cotransp PF00955.21 KFO97596.1 - 2.4e-195 650.2 20.5 4.5e-118 395.3 9.1 2.1 1 1 1 2 2 2 2 HCO3- transporter family Band_3_cyto PF07565.13 KFO97596.1 - 1e-76 258.3 0.6 2.5e-51 175.1 0.1 2.3 1 1 0 2 2 2 2 Band 3 cytoplasmic domain HMG_box PF00505.19 KFO97597.1 - 3.1e-55 184.5 64.0 5.1e-18 65.3 7.5 7.1 6 0 0 6 6 6 6 HMG (high mobility group) box HMG_box_5 PF14887.6 KFO97597.1 - 1.9e-54 181.6 45.2 4.1e-52 174.1 5.6 5.9 5 1 1 6 6 6 3 HMG (high mobility group) box 5 HMG_box_2 PF09011.10 KFO97597.1 - 1.7e-27 95.8 58.7 3.4e-08 33.9 0.3 7.0 7 0 0 7 7 7 6 HMG-box domain Evf PF18270.1 KFO97597.1 - 0.019 14.4 1.0 0.24 10.8 0.1 2.3 1 1 1 2 2 2 0 Virulence factor Evf ScsC_N PF18312.1 KFO97597.1 - 0.043 13.6 0.9 0.15 11.9 0.9 2.0 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain Ins134_P3_kin_N PF17927.1 KFO97597.1 - 0.044 14.2 2.7 4.8 7.6 0.1 3.2 2 1 1 3 3 3 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain Chlor_dismutase PF06778.12 KFO97597.1 - 0.12 11.9 0.1 0.12 11.9 0.1 3.0 3 0 0 3 3 3 0 Chlorite dismutase Perilipin PF03036.16 KFO97599.1 - 3.9e-170 566.1 17.2 4.6e-170 565.9 17.2 1.0 1 0 0 1 1 1 1 Perilipin family Syntaxin-6_N PF09177.11 KFO97599.1 - 0.0019 18.7 7.0 0.37 11.4 1.1 2.9 1 1 1 2 2 2 2 Syntaxin 6, N-terminal DUF2383 PF09537.10 KFO97599.1 - 0.022 15.1 2.6 4.1 7.8 0.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF2383) HBM PF16591.5 KFO97599.1 - 0.038 13.4 4.8 0.072 12.5 0.9 2.4 2 0 0 2 2 2 0 Helical bimodular sensor domain Baculo_PEP_C PF04513.12 KFO97599.1 - 2.7 8.0 9.2 9.1 6.3 0.2 3.4 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus HSP9_HSP12 PF04119.12 KFO97599.1 - 3.4 8.1 7.3 13 6.3 0.1 3.9 4 0 0 4 4 4 0 Heat shock protein 9/12 Snapin_Pallidin PF14712.6 KFO97599.1 - 3.8 8.0 7.4 1.1 9.7 1.7 2.7 3 0 0 3 3 3 0 Snapin/Pallidin DENN PF02141.21 KFO97600.1 - 1.1e-62 211.4 4.4 2.5e-62 210.2 4.4 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KFO97600.1 - 1.4e-14 54.5 0.4 5.7e-14 52.6 0.4 2.2 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KFO97600.1 - 1.7e-12 47.1 2.0 1.7e-12 47.1 2.0 2.2 2 0 0 2 2 2 1 dDENN domain PPR_2 PF13041.6 KFO97600.1 - 1.1e-05 25.5 0.0 0.00089 19.4 0.0 2.6 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.6 KFO97600.1 - 0.015 15.4 0.2 0.14 12.3 0.0 2.2 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Papo_T_antigen PF02380.15 KFO97600.1 - 0.049 13.8 4.0 0.082 13.1 1.2 2.7 2 0 0 2 2 2 0 T-antigen specific domain PPR PF01535.20 KFO97600.1 - 0.11 12.8 0.0 0.35 11.2 0.0 1.9 1 0 0 1 1 1 0 PPR repeat Ribosomal_S6e PF01092.19 KFO97601.1 - 2.3e-63 211.7 1.4 5.8e-63 210.5 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S6e DUF4574 PF15141.6 KFO97601.1 - 1.3 9.0 5.8 2.3 8.2 5.8 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Na_Ca_ex PF01699.24 KFO97602.1 - 9.8e-60 200.9 51.6 4.6e-31 107.8 21.9 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein AHD PF17793.1 KFO97603.1 - 1.9e-27 94.8 1.4 3.6e-27 93.9 1.4 1.5 1 0 0 1 1 1 1 ANC1 homology domain (AHD) YEATS PF03366.16 KFO97603.1 - 3.5e-08 33.3 0.0 6.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 YEATS family BET PF17035.5 KFO97603.1 - 0.045 13.9 0.2 0.1 12.8 0.2 1.6 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation Focadhesin PF11229.8 KFO97604.1 - 5.4e-294 976.0 9.9 8.4e-294 975.3 9.9 1.3 1 0 0 1 1 1 1 Focadhesin DUF3730 PF12530.8 KFO97604.1 - 9.8e-68 228.1 1.7 9.8e-68 228.1 1.7 4.0 5 0 0 5 5 5 1 Protein of unknown function (DUF3730) TAF6_C PF07571.13 KFO97604.1 - 0.085 13.2 0.2 25 5.3 0.0 4.4 4 0 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain PTPLA PF04387.14 KFO97605.1 - 1.1e-38 132.5 8.9 1.7e-38 131.9 8.9 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Interferon PF00143.19 KFO97606.1 - 3.6e-46 157.3 9.8 4.1e-46 157.1 9.8 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain ATP-synt_Z PF16594.5 KFO97606.1 - 0.026 14.0 1.1 0.051 13.1 1.1 1.3 1 0 0 1 1 1 0 Putative AtpZ or ATP-synthase-associated ResIII PF04851.15 KFO97606.1 - 0.31 11.0 3.2 0.44 10.5 3.2 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PDZ PF00595.24 KFO97607.1 - 1.8e-45 153.2 7.5 2.5e-16 59.8 0.3 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 KFO97607.1 - 7.8e-22 76.9 3.7 9.9e-07 28.5 0.0 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 KFO97607.1 - 2.1e-15 56.8 2.3 0.00016 21.9 0.1 3.6 3 0 0 3 3 3 3 PDZ domain Guanylate_kin PF00625.21 KFO97607.1 - 2.2e-13 50.3 0.1 4.6e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.17 KFO97607.1 - 5.4e-08 32.4 0.6 8.7e-07 28.5 0.0 3.2 4 0 0 4 4 4 1 Variant SH3 domain SH3_1 PF00018.28 KFO97607.1 - 9.5e-05 21.9 0.0 0.0032 17.0 0.0 3.2 2 0 0 2 2 2 1 SH3 domain Frataxin_Cyay PF01491.16 KFO97608.1 - 4.1e-37 126.5 0.0 4.7e-37 126.4 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain PIP5K PF01504.18 KFO97609.1 - 9.3e-91 303.8 0.1 1.3e-90 303.4 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Peptidase_S8 PF00082.22 KFO97610.1 - 2.3e-33 115.7 2.8 2.3e-31 109.2 2.8 2.3 1 1 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KFO97610.1 - 2.6e-31 107.5 0.0 5.1e-31 106.5 0.0 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain GF_recep_IV PF14843.6 KFO97610.1 - 7.5e-14 51.7 89.9 2.1e-09 37.3 41.0 3.7 1 1 2 3 3 3 3 Growth factor receptor domain IV PLAC PF08686.11 KFO97610.1 - 1.2e-12 48.3 7.4 1.2e-12 48.3 7.4 4.8 5 0 0 5 5 5 1 PLAC (protease and lacunin) domain S8_pro-domain PF16470.5 KFO97610.1 - 1.7e-12 47.9 0.6 3.3e-12 47.0 0.6 1.5 1 0 0 1 1 1 1 Peptidase S8 pro-domain Furin-like_2 PF15913.5 KFO97610.1 - 5.1e-12 45.9 73.0 6.7e-06 26.2 20.2 4.7 1 1 2 3 3 3 3 Furin-like repeat, cysteine-rich VSP PF03302.13 KFO97610.1 - 4.6e-07 29.0 79.2 0.0019 17.2 15.6 5.5 2 1 4 6 6 6 4 Giardia variant-specific surface protein DUF4215 PF13948.6 KFO97610.1 - 0.014 15.8 15.5 0.014 15.8 15.5 7.1 5 2 1 6 6 6 0 Domain of unknown function (DUF4215) Ank_2 PF12796.7 KFO97612.1 - 2.6e-24 85.6 3.2 3.7e-16 59.5 0.6 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFO97612.1 - 4.7e-22 77.8 6.1 5e-09 36.2 0.3 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFO97612.1 - 7.4e-16 58.3 0.4 1.1e-07 32.3 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SH3_1 PF00018.28 KFO97612.1 - 1.4e-14 53.5 0.0 2.5e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Ank PF00023.30 KFO97612.1 - 1.3e-13 50.8 0.4 2.4e-05 24.6 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat SH3_9 PF14604.6 KFO97612.1 - 1.5e-12 47.2 0.0 2.3e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFO97612.1 - 2.7e-12 46.2 0.0 5.3e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ank_3 PF13606.6 KFO97612.1 - 3.9e-10 39.1 0.1 0.014 15.9 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat AAA_18 PF13238.6 KFO97613.1 - 8e-12 45.8 0.0 1.3e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain N2227 PF07942.12 KFO97614.1 - 7e-112 373.1 0.2 8.4e-112 372.8 0.2 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.12 KFO97614.1 - 0.03 15.0 0.0 0.07 13.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KFO97614.1 - 0.033 14.9 0.0 0.11 13.2 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain RhoGAP PF00620.27 KFO97614.1 - 0.043 13.6 0.5 1.2 8.9 0.3 2.3 1 1 1 2 2 2 0 RhoGAP domain Methyltransf_23 PF13489.6 KFO97614.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 KFO97614.1 - 0.21 12.6 0.0 0.55 11.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain LSDAT_euk PF18139.1 KFO97615.1 - 3.4e-119 397.1 0.0 5e-119 396.6 0.0 1.3 1 0 0 1 1 1 1 SLOG in TRPM TRPM_tetra PF16519.5 KFO97615.1 - 8.6e-26 89.8 2.0 3.1e-25 88.0 2.0 2.1 1 0 0 1 1 1 1 Tetramerisation domain of TRPM LSDAT_prok PF18171.1 KFO97615.1 - 4.9e-15 55.3 0.1 9e-15 54.4 0.1 1.4 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 KFO97615.1 - 1.5e-11 44.1 16.4 2.4e-11 43.4 16.4 1.3 1 0 0 1 1 1 1 Ion transport protein zf-C4 PF00105.18 KFO97616.1 - 2.3e-33 114.5 12.3 5.4e-33 113.3 12.3 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFO97616.1 - 6.6e-24 84.6 2.4 6.6e-24 84.6 2.4 1.8 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor Yae1_N PF09811.9 KFO97617.1 - 2.7e-15 55.8 52.4 1.8e+04 -17.2 52.4 5.1 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Yae1_N PF09811.9 KFO97618.1 - 1.1e-17 63.4 63.8 1.8e+04 -28.6 63.8 6.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Annexin PF00191.20 KFO97619.1 - 2.2e-84 277.5 14.9 8.3e-24 83.4 0.5 4.1 4 0 0 4 4 4 4 Annexin Myb_DNA-bind_7 PF15963.5 KFO97619.1 - 0.0025 17.7 1.4 2.8 7.9 0.0 3.5 2 1 1 3 3 3 2 Myb DNA-binding like DrrA_P4M PF14860.6 KFO97619.1 - 0.004 17.0 0.7 0.92 9.4 0.2 2.7 2 0 0 2 2 2 2 DrrA phosphatidylinositol 4-phosphate binding domain ZirS_C PF16583.5 KFO97619.1 - 0.08 12.5 0.0 0.46 10.1 0.0 2.0 2 0 0 2 2 2 0 Zinc-regulated secreted antivirulence protein C-terminal domain Aldedh PF00171.22 KFO97620.1 - 1.6e-183 610.5 0.0 1.8e-183 610.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KFO97620.1 - 0.096 12.1 0.0 2.8 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) TMC PF07810.13 KFO97621.1 - 1.2e-37 128.9 3.4 3.3e-37 127.5 3.4 1.8 1 0 0 1 1 1 1 TMC domain Zip PF02535.22 KFO97621.1 - 6 6.0 7.9 17 4.5 7.9 1.8 1 0 0 1 1 1 0 ZIP Zinc transporter zf-A20 PF01754.16 KFO97622.1 - 8.3e-13 48.0 8.7 2.6e-12 46.4 8.7 1.9 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.16 KFO97622.1 - 1.9e-09 37.5 8.2 1.9e-09 37.5 8.2 1.9 2 0 0 2 2 2 1 AN1-like Zinc finger E3_UbLigase_RBR PF18091.1 KFO97622.1 - 0.064 13.4 0.1 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 E3 Ubiquitin Ligase RBR C-terminal domain FAM53 PF15242.6 KFO97622.1 - 0.1 12.4 9.4 0.14 12.0 9.4 1.1 1 0 0 1 1 1 0 Family of FAM53 Amidohydro_1 PF01979.20 KFO97623.1 - 3.3e-69 233.8 0.0 4e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFO97623.1 - 4.8e-10 39.5 0.0 1.8e-07 31.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family DUF2039 PF10217.9 KFO97624.1 - 5.8e-25 87.4 11.2 6.4e-25 87.3 11.2 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Cript PF10235.9 KFO97624.1 - 0.00017 22.1 7.0 0.00017 22.1 7.0 1.7 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT zinc-ribbons_6 PF07191.12 KFO97624.1 - 0.0015 18.5 8.0 0.0022 17.9 8.0 1.2 1 0 0 1 1 1 1 zinc-ribbons DZR PF12773.7 KFO97624.1 - 0.2 11.7 10.3 1.9 8.6 5.1 2.5 1 1 1 2 2 2 0 Double zinc ribbon Hydrolase_4 PF12146.8 KFO97625.1 - 6.3e-13 48.5 0.0 4.3e-07 29.5 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFO97625.1 - 1.8e-08 34.4 0.1 0.00038 20.2 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFO97625.1 - 3.1e-08 33.4 0.0 5.4e-06 26.0 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KFO97625.1 - 1.1e-07 32.7 0.0 3.7e-05 24.4 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.18 KFO97625.1 - 0.00079 19.0 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 KFO97625.1 - 0.0033 17.2 0.0 0.012 15.4 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 KFO97625.1 - 0.0045 16.7 0.0 0.0068 16.1 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) UPF0227 PF05728.12 KFO97625.1 - 0.0053 16.7 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Asp2 PF16929.5 KFO97625.1 - 0.012 14.7 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter DUF818 PF05677.12 KFO97625.1 - 0.022 13.7 0.1 0.032 13.2 0.1 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.16 KFO97625.1 - 0.062 13.1 0.0 0.35 10.6 0.0 2.0 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase ILEI PF15711.5 KFO97626.1 - 1.6e-35 121.5 0.1 1.4e-20 73.5 0.0 3.5 3 0 0 3 3 3 2 Interleukin-like EMT inducer G8 PF10162.9 KFO97626.1 - 1.9e-25 89.3 0.0 4.4e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 G8 domain PADR1 PF08063.12 KFO97626.1 - 0.029 14.2 1.1 8.9 6.2 0.1 3.0 2 0 0 2 2 2 0 PADR1 (NUC008) domain Lar_restr_allev PF14354.6 KFO97626.1 - 0.66 10.4 2.4 9.8 6.7 0.1 2.6 2 0 0 2 2 2 0 Restriction alleviation protein Lar LSDAT_euk PF18139.1 KFO97627.1 - 2e-125 417.6 0.1 3e-125 417.0 0.1 1.3 1 0 0 1 1 1 1 SLOG in TRPM TRPM_tetra PF16519.5 KFO97627.1 - 3.9e-24 84.5 6.1 1e-23 83.2 6.1 1.8 1 0 0 1 1 1 1 Tetramerisation domain of TRPM Ion_trans PF00520.31 KFO97627.1 - 3.4e-18 65.8 17.1 5.3e-18 65.1 17.1 1.3 1 0 0 1 1 1 1 Ion transport protein LSDAT_prok PF18171.1 KFO97627.1 - 1.6e-17 63.4 0.1 3e-17 62.5 0.1 1.3 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote zf-C2H2 PF00096.26 KFO97628.1 - 1.3e-12 47.4 12.0 4.5e-06 26.8 1.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO97628.1 - 2.3e-10 40.4 8.5 5.7e-09 36.0 2.7 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFO97628.1 - 1.8e-08 34.5 10.2 0.00018 22.1 2.8 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KFO97628.1 - 2.8e-05 24.7 1.8 0.0027 18.3 0.3 2.0 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KFO97628.1 - 8.7e-05 22.4 3.5 0.025 14.6 0.9 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO97628.1 - 0.0023 18.2 1.5 0.2 12.0 0.3 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFO97628.1 - 0.0034 17.7 1.7 0.14 12.6 0.3 2.4 1 1 2 3 3 3 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFO97628.1 - 0.0054 17.0 2.5 0.0086 16.4 2.5 1.4 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 KFO97628.1 - 0.0056 17.0 0.9 0.0066 16.7 0.9 1.0 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_9 PF16293.5 KFO97628.1 - 0.057 13.3 0.2 0.97 9.3 0.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-LYAR PF08790.11 KFO97628.1 - 0.083 12.8 2.7 3 7.8 0.4 2.6 2 1 0 2 2 2 0 LYAR-type C2HC zinc finger Zn-C2H2_12 PF18112.1 KFO97628.1 - 0.32 11.5 3.8 0.51 10.8 1.6 2.3 2 1 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain MAM PF00629.23 KFO97629.1 - 4.4e-130 429.8 0.0 1.1e-42 145.7 0.0 4.0 4 0 0 4 4 4 4 MAM domain, meprin/A5/mu PPTA PF01239.22 KFO97630.1 - 2.2e-23 81.2 11.3 1.8e-07 30.6 0.2 6.5 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat PID PF00640.23 KFO97631.1 - 6.4e-52 175.3 1.0 1.4e-51 174.2 1.0 1.6 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.24 KFO97631.1 - 2e-27 95.4 11.8 2e-15 56.9 1.0 3.3 4 0 0 4 4 4 2 PDZ domain PDZ_6 PF17820.1 KFO97631.1 - 3.7e-16 58.7 0.8 4.2e-08 32.9 0.1 3.0 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 KFO97631.1 - 5.1e-07 29.9 0.0 6.6e-05 23.1 0.0 2.9 3 0 0 3 3 3 1 PDZ domain NRho PF16733.5 KFO97631.1 - 0.068 13.2 0.2 0.29 11.2 0.0 2.1 2 0 0 2 2 2 0 Rhomboid N-terminal domain Flavokinase PF01687.17 KFO97632.1 - 1e-24 87.0 0.0 1.1e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase BNIP2 PF12496.8 KFO97633.1 - 1.2e-42 145.6 3.9 1.6e-42 145.2 3.9 1.1 1 0 0 1 1 1 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CRAL_TRIO_2 PF13716.6 KFO97633.1 - 2.9e-31 108.5 0.3 4.8e-31 107.7 0.3 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KFO97633.1 - 5.6e-10 39.2 0.4 9.9e-10 38.4 0.4 1.4 1 1 0 1 1 1 1 CRAL/TRIO domain DHHA2 PF02833.14 KFO97634.1 - 0.0011 19.1 0.1 0.0027 17.9 0.0 1.6 2 0 0 2 2 2 1 DHHA2 domain FUR PF01475.19 KFO97634.1 - 0.022 14.9 0.1 0.17 12.0 0.1 2.2 2 1 0 2 2 2 0 Ferric uptake regulator family SAM_Ste50p PF09235.10 KFO97634.1 - 0.046 14.0 0.0 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 Ste50p, sterile alpha motif G-alpha PF00503.20 KFO97635.1 - 1.7e-109 366.2 1.7 1.9e-109 366.1 1.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFO97635.1 - 9.1e-12 44.8 0.2 4.5e-11 42.5 0.2 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family Aminotran_5 PF00266.19 KFO97636.1 - 2.7e-63 214.1 0.0 3.1e-63 214.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V SBP_bac_6 PF13343.6 KFO97636.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Lipase_GDSL_2 PF13472.6 KFO97637.1 - 0.00085 19.8 0.0 0.0031 18.0 0.0 1.9 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 KFO97637.1 - 0.0048 16.2 0.0 0.0089 15.3 0.0 1.3 1 0 0 1 1 1 1 OSK domain Tmemb_cc2 PF10267.9 KFO97637.1 - 0.065 12.4 0.5 0.094 11.8 0.5 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Lipase_GDSL PF00657.22 KFO97637.1 - 0.22 11.5 0.0 0.85 9.6 0.0 1.9 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase TLE_N PF03920.15 KFO97638.1 - 6.5e-36 123.3 7.7 9.6e-36 122.7 7.7 1.3 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.32 KFO97638.1 - 7.3e-18 64.6 18.1 0.014 16.2 0.8 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO97638.1 - 2e-08 34.4 0.1 0.16 12.3 0.0 4.6 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFO97638.1 - 0.012 14.9 0.0 7 5.9 0.2 2.6 2 1 0 2 2 2 0 WD40-like domain Cytochrom_D1 PF02239.16 KFO97638.1 - 0.032 12.8 0.0 1.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 KFO97638.1 - 0.73 10.4 2.9 21 5.8 0.0 4.2 4 1 1 5 5 5 0 PQQ-like domain TLE_N PF03920.15 KFO97639.1 - 3.3e-53 179.3 10.6 4.7e-53 178.8 10.6 1.2 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.32 KFO97639.1 - 9.3e-17 61.1 18.2 0.015 16.2 0.8 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO97639.1 - 1e-07 32.2 0.0 0.12 12.7 0.0 4.3 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFO97639.1 - 0.016 14.6 0.0 7.3 5.8 0.2 2.7 2 1 0 3 3 3 0 WD40-like domain Cytochrom_D1 PF02239.16 KFO97639.1 - 0.056 12.0 0.0 1.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Nup160 PF11715.8 KFO97639.1 - 0.1 11.2 0.5 3.5 6.2 0.0 2.5 2 1 0 3 3 3 0 Nucleoporin Nup120/160 Ribosomal_S18 PF01084.20 KFO97639.1 - 0.17 12.1 0.3 0.32 11.2 0.3 1.4 1 0 0 1 1 1 0 Ribosomal protein S18 Transketolase_N PF00456.21 KFO97639.1 - 0.18 10.8 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Ras PF00071.22 KFO97640.1 - 5.2e-50 169.2 0.0 1.2e-49 168.1 0.0 1.6 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO97640.1 - 1.9e-30 105.6 0.0 4.4e-30 104.4 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO97640.1 - 5.1e-16 58.6 1.3 9.9e-16 57.7 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFO97640.1 - 1e-08 35.3 0.0 3.7e-08 33.5 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFO97640.1 - 0.0038 16.8 0.0 0.0038 16.8 0.0 2.4 2 1 0 2 2 1 1 Elongation factor Tu GTP binding domain KAP_NTPase PF07693.14 KFO97640.1 - 0.035 13.4 3.0 0.53 9.5 3.3 2.2 2 0 0 2 2 2 0 KAP family P-loop domain AAA_25 PF13481.6 KFO97640.1 - 0.22 11.1 2.6 1.9 8.0 0.0 3.0 2 1 1 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 KFO97640.1 - 0.23 11.4 2.9 4.3 7.2 0.0 3.3 3 1 1 4 4 4 0 RsgA GTPase Bac_RepA_C PF18008.1 KFO97640.1 - 0.31 11.4 4.0 6.6 7.2 0.2 2.8 2 0 0 2 2 2 0 Replication initiator protein A C-terminal domain GIT_CC PF16559.5 KFO97640.1 - 0.68 9.8 16.3 4.7 7.2 0.2 3.9 2 1 2 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor AAA_13 PF13166.6 KFO97640.1 - 0.69 8.5 22.9 1.1 7.9 22.9 1.2 1 0 0 1 1 1 0 AAA domain TTKRSYEDQ PF10212.9 KFO97640.1 - 0.84 8.6 19.6 0.24 10.3 16.2 1.8 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein AAA_33 PF13671.6 KFO97640.1 - 0.92 9.7 0.0 0.92 9.7 0.0 4.1 4 1 0 4 4 4 0 AAA domain GAS PF13851.6 KFO97640.1 - 1.4 8.3 35.8 0.04 13.3 25.5 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding NitrOD5 PF11537.8 KFO97640.1 - 1.8 8.7 8.4 2 8.6 3.3 2.8 3 0 0 3 3 3 0 Nitrosopumilus output domain 5 Ribosomal_S2 PF00318.20 KFO97640.1 - 2.4 7.3 0.0 2.4 7.3 0.0 3.1 2 1 1 3 3 3 0 Ribosomal protein S2 APG6_N PF17675.1 KFO97640.1 - 5.7 7.5 38.4 0.31 11.6 23.7 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region ECH_2 PF16113.5 KFO97640.1 - 6 6.3 10.0 10 5.5 10.0 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase ADIP PF11559.8 KFO97640.1 - 9.4 6.3 33.2 4.2 7.4 16.1 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FERM_M PF00373.18 KFO97641.1 - 2.4e-19 69.8 0.2 6.1e-19 68.6 0.0 1.8 2 0 0 2 2 2 1 FERM central domain FERM_C PF09380.10 KFO97641.1 - 4.3e-16 59.1 0.3 9.2e-16 58.0 0.3 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FA PF08736.11 KFO97641.1 - 6.8e-14 51.7 2.2 1.4e-13 50.7 2.2 1.5 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_N PF09379.10 KFO97641.1 - 3.4e-11 42.9 0.0 6.1e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 FERM N-terminal domain SKI PF01202.22 KFO97642.1 - 0.00025 21.2 0.0 0.0013 18.9 0.0 1.9 1 1 0 1 1 1 1 Shikimate kinase ubiquitin PF00240.23 KFO97643.1 - 1.9e-13 50.0 0.7 3.5e-13 49.1 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin family STI1 PF17830.1 KFO97643.1 - 2.4e-10 40.2 60.0 0.00013 21.9 10.2 6.5 3 2 3 6 6 6 5 STI1 domain UBA PF00627.31 KFO97643.1 - 1.4e-07 31.3 0.5 4.3e-07 29.7 0.5 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 KFO97643.1 - 0.002 17.9 0.1 0.0039 17.0 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RasGAP PF00616.19 KFO97643.1 - 0.0085 15.8 0.5 0.1 12.3 0.0 2.3 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase Rad60-SLD_2 PF13881.6 KFO97643.1 - 0.024 14.8 0.2 0.045 13.9 0.2 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like HOIP-UBA PF16678.5 KFO97643.1 - 0.031 14.3 0.5 0.075 13.0 0.1 1.8 2 0 0 2 2 2 0 HOIP UBA domain pair CUE PF02845.16 KFO97643.1 - 0.055 13.2 0.6 0.23 11.2 0.0 2.5 2 0 0 2 2 2 0 CUE domain DUF2407 PF10302.9 KFO97643.1 - 0.15 12.7 0.1 0.66 10.6 0.1 2.2 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Clathrin-link PF09268.10 KFO97643.1 - 1.8 8.0 15.9 6.4 6.2 0.1 5.2 5 0 0 5 5 5 0 Clathrin, heavy-chain linker TcdB_N PF12918.7 KFO97644.1 - 1.4 9.3 12.4 1.9 8.8 0.9 3.6 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain TSC22 PF01166.18 KFO97644.1 - 1.4 9.3 9.5 0.16 12.3 0.7 3.3 3 0 0 3 3 3 0 TSC-22/dip/bun family Kinesin PF00225.23 KFO97645.1 - 7.3e-111 370.3 1.2 7.3e-111 370.3 1.2 3.2 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KFO97645.1 - 1.7e-24 86.5 0.0 1.7e-24 86.5 0.0 3.4 3 0 0 3 3 3 1 Microtubule binding Hydrolase_6 PF13344.6 KFO97645.1 - 0.15 12.2 1.3 1.2 9.3 0.9 2.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase GlcNAc-1_reg PF18440.1 KFO97645.1 - 1 9.6 14.3 2.1 8.7 0.0 5.0 3 2 3 6 6 6 0 Putative GlcNAc-1 phosphotransferase regulatory domain Q_salvage PF10343.9 KFO97646.1 - 4e-91 305.5 0.0 4.5e-91 305.3 0.0 1.0 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family KH_1 PF00013.29 KFO97647.1 - 2.7e-44 148.8 14.8 4.7e-20 71.2 1.9 4.1 4 0 0 4 4 4 3 KH domain ROKNT PF08067.11 KFO97647.1 - 5.3e-23 81.0 11.6 8.9e-23 80.3 11.6 1.4 1 0 0 1 1 1 1 ROKNT (NUC014) domain KH_2 PF07650.17 KFO97647.1 - 1.7e-15 56.6 3.9 0.00065 19.5 0.5 4.1 4 0 0 4 4 4 3 KH domain KH_4 PF13083.6 KFO97647.1 - 3.5e-09 36.4 4.8 3.6e-06 26.8 0.0 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 KFO97647.1 - 0.00018 21.5 6.7 0.26 11.4 0.1 3.7 3 1 1 4 4 4 2 NusA-like KH domain MOEP19 PF16005.5 KFO97647.1 - 0.049 13.6 0.0 2.9 8.0 0.0 2.4 2 0 0 2 2 2 0 KH-like RNA-binding domain DJ-1_PfpI PF01965.24 KFO97647.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family RMI1_N PF08585.12 KFO97648.1 - 2.8e-55 187.5 0.2 4.9e-55 186.6 0.2 1.4 1 0 0 1 1 1 1 RecQ mediated genome instability protein RMI1_C PF16099.5 KFO97648.1 - 3.7e-44 150.0 0.0 1.1e-43 148.5 0.0 1.8 1 0 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold Nucleos_tra2_C PF07662.13 KFO97649.1 - 4.8e-78 261.7 6.1 1e-77 260.7 6.1 1.6 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KFO97649.1 - 2.8e-19 69.5 3.1 2.8e-19 69.5 3.1 3.6 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 KFO97649.1 - 6.9e-08 32.7 7.5 6.9e-08 32.7 7.5 3.8 4 0 0 4 4 4 1 Nucleoside recognition Pkinase_Tyr PF07714.17 KFO97650.1 - 5.6e-97 324.1 0.0 7.6e-97 323.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO97650.1 - 1.9e-48 165.2 0.0 2.7e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.16 KFO97650.1 - 3.5e-23 81.5 0.2 5.9e-13 48.7 0.1 2.6 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO97650.1 - 3.7e-17 62.7 4.9 3.4e-11 43.6 1.6 2.7 2 0 0 2 2 2 2 Immunoglobulin domain TPKR_C2 PF16920.5 KFO97650.1 - 2e-13 50.2 1.0 5.1e-13 48.9 0.4 2.1 2 0 0 2 2 2 1 Tyrosine-protein kinase receptor C2 Ig-like domain ig PF00047.25 KFO97650.1 - 2.2e-12 47.0 0.5 5.1e-08 33.0 0.2 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFO97650.1 - 9e-12 45.2 3.1 3e-08 33.9 0.6 2.7 2 0 0 2 2 2 2 Immunoglobulin domain LRR_8 PF13855.6 KFO97650.1 - 1.8e-09 37.3 2.1 5.1e-09 35.8 2.1 1.9 1 0 0 1 1 1 1 Leucine rich repeat C2-set_2 PF08205.12 KFO97650.1 - 0.00047 20.2 0.3 0.6 10.2 0.1 2.7 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFO97650.1 - 0.0012 19.0 0.6 1.2 9.4 0.0 3.2 1 1 2 3 3 3 2 Immunoglobulin V-set domain Ig_C17orf99 PF17736.1 KFO97650.1 - 0.0013 18.8 0.0 0.0028 17.7 0.0 1.6 1 0 0 1 1 1 1 C17orf99 Ig domain TMEM154 PF15102.6 KFO97650.1 - 0.0052 16.7 0.0 0.0095 15.9 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family Haspin_kinase PF12330.8 KFO97650.1 - 0.037 13.0 0.0 0.067 12.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain zf-RING_4 PF14570.6 KFO97651.1 - 3.5e-20 71.5 12.2 6.2e-20 70.7 12.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KFO97651.1 - 1.7e-06 27.8 7.4 3.3e-06 26.8 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KFO97651.1 - 8.3e-06 25.5 0.0 1.9e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 KFO97651.1 - 0.0035 17.7 11.0 0.0077 16.5 11.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFO97651.1 - 0.028 14.3 10.4 0.062 13.2 10.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFO97651.1 - 0.035 14.0 9.9 0.075 12.9 9.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 KFO97651.1 - 0.053 13.6 3.6 0.14 12.3 3.6 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_5 PF14634.6 KFO97651.1 - 0.43 10.6 8.9 0.84 9.7 8.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KFO97651.1 - 1.8 8.5 9.7 48 3.9 9.9 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Nup192 PF11894.8 KFO97652.1 - 0 1360.4 10.2 0 1360.2 10.2 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Arf PF00025.21 KFO97653.1 - 1.3e-75 252.7 0.1 1.4e-75 252.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFO97653.1 - 3.7e-15 56.2 0.1 4.9e-15 55.8 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFO97653.1 - 1.9e-13 50.4 0.0 2.1e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFO97653.1 - 1.8e-11 43.8 0.0 2.1e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFO97653.1 - 3e-11 43.1 0.6 3.5e-07 29.7 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KFO97653.1 - 3.1e-10 39.8 0.0 3.8e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFO97653.1 - 1.4e-05 25.2 0.0 2.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 KFO97653.1 - 0.0013 17.7 0.4 0.048 12.6 0.0 2.4 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 KFO97653.1 - 0.0062 16.1 0.3 0.049 13.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KFO97653.1 - 0.017 15.6 0.3 0.098 13.2 0.3 1.9 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KFO97653.1 - 0.019 15.5 0.0 0.024 15.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KFO97653.1 - 0.02 14.4 0.8 0.13 11.8 0.8 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B cobW PF02492.19 KFO97653.1 - 0.083 12.5 0.3 8.3 6.0 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KFO97653.1 - 0.084 12.8 0.1 13 5.7 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 KFO97653.1 - 0.14 11.9 0.3 3.9 7.2 0.1 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KFO97653.1 - 0.2 12.1 0.1 3.6 7.9 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain DRIM PF07539.12 KFO97654.1 - 2.2e-180 601.1 17.3 2.2e-180 601.1 17.3 3.3 3 0 0 3 3 3 2 Down-regulated in metastasis HEAT_2 PF13646.6 KFO97654.1 - 0.0061 16.9 0.0 0.58 10.6 0.0 4.4 5 0 0 5 5 5 1 HEAT repeats HEAT PF02985.22 KFO97654.1 - 0.018 15.2 1.5 49 4.6 0.2 5.7 5 0 0 5 5 5 0 HEAT repeat GatB_Yqey PF02637.18 KFO97654.1 - 0.067 13.1 7.1 0.11 12.4 0.2 3.7 4 0 0 4 4 4 0 GatB domain Arm PF00514.23 KFO97654.1 - 0.6 10.2 5.0 25 5.1 0.1 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Anoctamin PF04547.12 KFO97655.1 - 8.6e-160 532.4 12.6 1e-159 532.2 12.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KFO97655.1 - 6.5e-75 251.7 2.5 1.2e-74 250.9 2.5 1.4 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin GAS2 PF02187.17 KFO97656.1 - 3.2e-27 94.4 0.0 6e-27 93.5 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.31 KFO97656.1 - 2e-11 44.0 0.0 3.2e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain zf-C4 PF00105.18 KFO97657.1 - 8.6e-29 99.8 14.7 8.6e-29 99.8 14.7 1.7 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFO97657.1 - 1.1e-25 90.5 1.1 1.1e-25 90.5 1.1 2.3 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor Pkinase PF00069.25 KFO97658.1 - 2.2e-26 92.8 0.0 4e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO97658.1 - 3.2e-15 56.1 0.0 1.3e-14 54.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase XRN_M PF17846.1 KFO97658.1 - 0.042 12.8 0.8 0.083 11.8 0.8 1.4 1 0 0 1 1 1 0 Xrn1 helical domain DEP PF00610.21 KFO97659.1 - 1.7e-19 69.7 2.0 5.7e-18 64.8 0.2 2.8 3 0 0 3 3 3 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF2185 PF09951.9 KFO97659.1 - 0.038 13.8 0.0 0.089 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2185) Repressor_Mnt PF11423.8 KFO97659.1 - 2.4 8.0 4.5 20 5.1 0.0 3.3 3 0 0 3 3 3 0 Regulatory protein Mnt Actin PF00022.19 KFO97660.1 - 2.6e-78 263.5 0.0 3.9e-77 259.6 0.0 1.9 1 1 0 1 1 1 1 Actin EcoRII-C PF09019.11 KFO97660.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 EcoRII C terminal Aldo_ket_red PF00248.21 KFO97661.1 - 8.2e-53 179.5 0.0 1.2e-52 178.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KFO97662.1 - 2.1e-52 178.2 0.0 6.2e-52 176.6 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KFO97663.1 - 1.7e-48 165.4 0.0 2.5e-48 164.8 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family His_Phos_1 PF00300.22 KFO97664.1 - 1.1e-34 119.8 0.0 5.3e-27 94.8 0.1 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Caldesmon PF02029.15 KFO97666.1 - 1.4e-155 518.8 200.2 3.9e-124 415.1 30.0 3.0 1 1 2 3 3 3 3 Caldesmon Aldo_ket_red PF00248.21 KFO97667.1 - 1.7e-56 191.6 0.0 2.7e-56 190.9 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family Ras PF00071.22 KFO97668.1 - 2.3e-26 92.4 0.0 2.5e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO97668.1 - 8.6e-05 22.8 0.0 0.00011 22.4 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO97668.1 - 0.0045 16.5 0.0 0.0054 16.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Y_phosphatase PF00102.27 KFO97670.1 - 5.8e-84 281.3 1.8 1.3e-83 280.1 1.8 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase fn3 PF00041.21 KFO97670.1 - 3.4e-29 101.0 16.1 2.4e-08 34.2 0.6 6.2 5 0 0 5 5 5 5 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFO97670.1 - 2.2e-05 25.0 4.4 0.66 10.6 0.4 4.3 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Y_phosphatase3 PF13350.6 KFO97670.1 - 4.5e-05 23.5 0.0 8.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KFO97670.1 - 0.00017 21.4 0.0 0.00048 20.0 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFO97670.1 - 0.00043 20.4 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate PTB PF08416.13 KFO97671.1 - 1.3e-53 180.6 1.4 2.4e-53 179.8 1.4 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SAM_3 PF18016.1 KFO97671.1 - 2.5e-23 81.6 0.0 5.9e-23 80.4 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 KFO97671.1 - 1.1e-09 37.7 0.1 2.4e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 SH3 domain PID PF00640.23 KFO97671.1 - 2.5e-06 27.6 2.1 2.9e-06 27.4 0.3 2.0 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) SH3_9 PF14604.6 KFO97671.1 - 3.8e-06 26.6 0.0 7.9e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFO97671.1 - 1.9e-05 24.3 0.0 3.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFO97671.1 - 0.001 19.3 0.1 0.0028 17.9 0.1 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_10 PF17902.1 KFO97671.1 - 0.0086 16.1 0.1 0.03 14.4 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SAM_PNT PF02198.16 KFO97671.1 - 0.084 12.9 0.0 0.29 11.1 0.0 1.9 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain DUF737 PF05300.11 KFO97671.1 - 1.7 9.0 7.9 0.23 11.8 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF737) DeoC PF01791.9 KFO97672.1 - 1.4e-26 93.6 0.0 1.6e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase PTR2 PF00854.21 KFO97673.1 - 3.9e-42 144.5 11.3 5.4e-42 144.0 11.3 1.1 1 0 0 1 1 1 1 POT family MAPEG PF01124.18 KFO97674.1 - 1.7e-26 92.7 0.9 1.9e-26 92.5 0.9 1.0 1 0 0 1 1 1 1 MAPEG family LIM PF00412.22 KFO97675.1 - 1.4e-30 105.2 22.1 3.8e-15 55.9 8.1 2.0 2 0 0 2 2 2 2 LIM domain Ras PF00071.22 KFO97676.1 - 3.4e-19 69.0 0.0 4.5e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Taxilin PF09728.9 KFO97677.1 - 2.8e-118 394.6 77.0 3.2e-118 394.4 77.0 1.0 1 0 0 1 1 1 1 Myosin-like coiled-coil protein HTH_26 PF13443.6 KFO97677.1 - 0.056 13.9 1.4 0.35 11.3 0.0 3.1 3 1 0 3 3 3 0 Cro/C1-type HTH DNA-binding domain STOP PF05217.12 KFO97677.1 - 0.069 13.5 0.5 0.3 11.4 0.5 2.2 1 0 0 1 1 1 0 STOP protein Metallothio_2 PF01439.18 KFO97677.1 - 0.71 10.8 1.6 11 7.0 0.1 2.7 2 0 0 2 2 2 0 Metallothionein RFamide_26RFa PF11109.8 KFO97677.1 - 1.4 9.4 13.5 0.14 12.7 0.5 2.9 2 1 1 3 3 3 0 Orexigenic neuropeptide Qrfp/P518 APG6_N PF17675.1 KFO97677.1 - 8.4 6.9 73.9 3.3 8.3 9.5 3.9 1 1 3 4 4 4 0 Apg6 coiled-coil region CAF1C_H4-bd PF12265.8 KFO97678.1 - 3.7e-27 94.4 1.7 2.6e-26 91.7 0.6 2.7 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KFO97678.1 - 1.8e-26 91.9 15.8 3.2e-07 30.9 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO97678.1 - 1.1e-05 25.6 0.8 0.0052 17.1 0.1 3.6 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFO97678.1 - 8e-05 22.6 0.2 0.017 15.0 0.0 2.9 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A EF-hand_4 PF12763.7 KFO97679.1 - 2e-12 47.0 0.0 4.5e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 KFO97679.1 - 0.016 15.7 0.0 0.032 14.7 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 KFO97679.1 - 0.026 14.0 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.6 KFO97679.1 - 0.068 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair CHDCT2 PF08074.11 KFO97679.1 - 0.17 12.1 0.7 0.41 10.8 0.7 1.6 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Lectin_N PF03954.14 KFO97679.1 - 0.29 10.9 2.6 8.6 6.1 0.0 2.5 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain NHS PF15273.6 KFO97680.1 - 3.1e-216 720.4 46.7 3.1e-216 720.4 46.7 2.3 2 0 0 2 2 2 1 NHS-like BEN PF10523.9 KFO97681.1 - 3.8e-24 84.7 0.1 1.2e-10 41.4 0.0 2.5 2 0 0 2 2 2 2 BEN domain HJURP_C PF12347.8 KFO97681.1 - 0.032 14.3 0.0 0.098 12.7 0.0 1.8 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat DUF1647 PF07801.11 KFO97681.1 - 0.067 12.9 0.0 10 5.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) DUF4694 PF15765.5 KFO97682.1 - 0.037 14.0 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4694) Pkinase PF00069.25 KFO97683.1 - 2.8e-74 249.8 0.0 4.3e-74 249.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO97683.1 - 1.8e-34 119.2 0.0 3e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFO97683.1 - 9.9e-05 21.4 0.5 0.00019 20.5 0.5 1.4 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KFO97683.1 - 0.0015 18.2 0.3 1.2 8.7 0.0 2.6 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KFO97683.1 - 0.011 15.3 0.8 0.011 15.3 0.8 1.8 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 KFO97683.1 - 0.3 11.0 1.4 2.6 7.9 0.2 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family F5_F8_type_C PF00754.25 KFO97684.1 - 7.9e-31 106.8 0.3 1e-30 106.4 0.3 1.1 1 0 0 1 1 1 1 F5/8 type C domain KorB_C PF06613.11 KFO97684.1 - 0.00098 19.1 0.3 0.0053 16.7 0.0 2.0 2 0 0 2 2 2 1 KorB C-terminal beta-barrel domain Metallophos PF00149.28 KFO97685.1 - 6.4e-27 95.4 0.2 1.2e-26 94.5 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 KFO97685.1 - 2.6e-18 66.2 2.7 9.9e-11 41.9 2.8 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFO97685.1 - 3.4e-16 57.5 0.1 1.4e-05 24.3 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KFO97685.1 - 1.6e-11 43.2 0.1 0.0029 17.4 0.1 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KFO97685.1 - 3.5e-09 35.7 0.4 0.0002 20.7 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFO97685.1 - 2.4e-07 30.5 2.5 0.0012 18.6 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair PPP5 PF08321.12 KFO97685.1 - 3e-06 27.4 0.0 9.7e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 PPP5 TPR repeat region PRD_Mga PF08270.11 KFO97685.1 - 0.016 14.9 0.2 0.037 13.7 0.2 1.5 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) PRD domain IQ PF00612.27 KFO97685.1 - 0.084 12.7 0.7 0.18 11.7 0.7 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif EF-hand_4 PF12763.7 KFO97685.1 - 0.54 10.2 3.1 1.8 8.6 0.4 2.8 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Glyco_hydro_15 PF00723.21 KFO97686.1 - 7.3e-182 605.1 0.0 8.7e-182 604.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 7tm_2 PF00002.24 KFO97687.1 - 2.6e-55 187.4 22.1 5.9e-55 186.2 22.1 1.6 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 KFO97687.1 - 2.3e-17 63.2 4.1 7.8e-17 61.5 4.1 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif TraL PF07178.11 KFO97687.1 - 0.094 13.2 3.0 3.2 8.3 0.0 3.4 3 0 0 3 3 3 0 TraL protein E1_dh PF00676.20 KFO97688.1 - 5.1e-123 409.8 0.0 6e-123 409.6 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KFO97688.1 - 0.002 17.9 0.3 0.0037 17.1 0.3 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KFO97688.1 - 0.0069 15.6 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase SH3_9 PF14604.6 KFO97689.1 - 2.5e-54 180.9 2.9 4.2e-17 61.8 0.1 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 KFO97689.1 - 2.4e-43 145.5 7.7 4.3e-15 55.1 0.3 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 KFO97689.1 - 8.3e-43 143.9 4.2 2.2e-13 49.6 0.1 3.4 3 0 0 3 3 3 3 Variant SH3 domain XFP PF03894.15 KFO97689.1 - 0.00023 20.9 0.0 1.8 8.3 0.0 3.2 2 1 1 3 3 3 2 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Tmemb_cc2 PF10267.9 KFO97689.1 - 0.0077 15.4 0.4 0.013 14.7 0.4 1.3 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein TrkA_C PF02080.21 KFO97689.1 - 0.24 11.2 1.4 5.2 7.0 0.1 2.9 3 0 0 3 3 3 0 TrkA-C domain THRAP3_BCLAF1 PF15440.6 KFO97690.1 - 2.5e-71 241.7 7.8 2.8e-71 241.5 7.8 1.0 1 0 0 1 1 1 1 THRAP3/BCLAF1 family MAP7 PF05672.11 KFO97691.1 - 1.5e-46 158.1 88.2 1.5e-46 158.1 88.2 3.2 3 1 0 3 3 3 1 MAP7 (E-MAP-115) family eIF-1a PF01176.19 KFO97692.1 - 1.4e-21 76.0 0.1 1.8e-21 75.7 0.1 1.1 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Pkinase PF00069.25 KFO97693.1 - 4.6e-144 478.6 0.0 3.1e-71 239.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFO97693.1 - 4.5e-78 262.1 0.0 5.5e-42 143.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFO97693.1 - 8.5e-14 51.5 0.0 3.4e-07 29.9 0.0 2.7 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 KFO97693.1 - 5.5e-11 42.2 0.1 1.7e-05 24.3 0.0 3.0 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFO97693.1 - 5.8e-09 35.2 0.0 0.00047 19.1 0.0 2.4 3 0 0 3 3 3 2 Fungal protein kinase Pkinase_C PF00433.24 KFO97693.1 - 1.7e-07 31.8 1.8 4.1e-07 30.6 1.8 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KFO97693.1 - 6e-07 28.7 0.2 0.0076 15.2 0.1 2.2 2 0 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 KFO97693.1 - 1.3e-05 25.2 0.0 0.14 12.1 0.0 3.0 2 1 0 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 KFO97693.1 - 0.00034 20.3 0.1 2.9 7.5 0.0 3.3 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 KFO97693.1 - 0.00079 19.0 0.1 0.32 10.5 0.0 2.9 3 0 0 3 3 3 1 PhoP regulatory network protein YrbL RIO1 PF01163.22 KFO97693.1 - 0.076 12.6 0.3 2.7 7.5 0.0 2.5 3 0 0 3 3 3 0 RIO1 family tRNA-synt_1f PF01921.18 KFO97693.1 - 0.087 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) DUF1170 PF06663.13 KFO97694.1 - 2.8e-63 213.5 9.9 4.5e-62 209.5 9.3 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1170) CRIC_ras_sig PF10534.9 KFO97694.1 - 2.3e-39 133.5 0.5 7.9e-39 131.7 0.1 2.2 2 0 0 2 2 2 1 Connector enhancer of kinase suppressor of ras SAM_1 PF00536.30 KFO97694.1 - 1.9e-15 57.1 1.8 7.3e-15 55.2 0.3 2.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH PF00169.29 KFO97694.1 - 6.4e-15 55.5 5.6 1.5e-14 54.3 4.2 2.4 2 0 0 2 2 2 1 PH domain SAM_2 PF07647.17 KFO97694.1 - 4.7e-10 39.4 0.7 3.3e-09 36.7 0.3 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PDZ PF00595.24 KFO97694.1 - 5.3e-09 36.3 0.1 1.5e-08 34.9 0.0 1.7 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFO97694.1 - 3.7e-08 33.1 0.0 1e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PH_9 PF15410.6 KFO97694.1 - 0.00082 19.7 3.0 0.15 12.4 2.9 3.5 3 1 0 3 3 3 1 Pleckstrin homology domain PDZ_2 PF13180.6 KFO97694.1 - 0.0018 18.6 0.2 0.033 14.5 0.0 2.6 2 0 0 2 2 2 1 PDZ domain Adaptin_binding PF10199.9 KFO97694.1 - 0.1 13.2 6.4 45 4.7 0.0 2.9 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 PH_13 PF16652.5 KFO97694.1 - 0.43 10.4 4.0 0.15 11.9 0.2 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain PH_11 PF15413.6 KFO97694.1 - 0.52 10.8 18.7 0.11 13.0 10.6 3.5 3 1 0 3 3 2 0 Pleckstrin homology domain ATG11 PF10377.9 KFO97694.1 - 9.1 6.4 9.7 0.077 13.1 0.7 2.1 2 0 0 2 2 1 0 Autophagy-related protein 11 FAM176 PF14851.6 KFO97694.1 - 9.6 5.9 8.7 6 6.5 5.7 2.2 2 0 0 2 2 2 0 FAM176 family Kelch_1 PF01344.25 KFO97695.1 - 1.5e-37 126.9 0.0 8.3e-09 34.9 0.0 5.9 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KFO97695.1 - 6.1e-34 115.2 1.1 1.5e-08 34.6 0.0 6.4 1 1 5 6 6 6 6 Kelch motif BTB PF00651.31 KFO97695.1 - 1.1e-26 93.2 1.3 1.7e-26 92.6 0.6 1.7 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.6 KFO97695.1 - 2.7e-26 91.3 0.3 4.4e-06 26.6 0.0 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 KFO97695.1 - 1.9e-20 72.7 0.2 0.022 15.0 0.0 6.7 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KFO97695.1 - 4.7e-15 54.9 1.0 0.00038 20.3 0.0 5.5 4 2 0 4 4 4 4 Kelch motif BACK PF07707.15 KFO97695.1 - 5.2e-10 39.3 0.1 1.1e-09 38.4 0.1 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 KFO97695.1 - 8.6e-10 38.4 2.3 0.0016 18.4 0.0 5.8 6 0 0 6 6 6 2 Kelch motif Chisel PF15355.6 KFO97696.1 - 3.6e-40 136.1 3.2 3.9e-40 136.0 3.2 1.0 1 0 0 1 1 1 1 Stretch-responsive small skeletal muscle X protein, Chisel Peptidase_M50 PF02163.22 KFO97697.1 - 4.9e-32 111.2 2.4 2.5e-30 105.6 0.2 2.3 2 0 0 2 2 2 2 Peptidase family M50 PDZ_2 PF13180.6 KFO97697.1 - 0.0039 17.5 0.0 0.0072 16.6 0.0 1.3 1 0 0 1 1 1 1 PDZ domain SpmSyn_N PF17950.1 KFO97698.1 - 1.1e-49 166.6 0.1 1.9e-49 165.8 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase N -terminal Spermine_synth PF01564.17 KFO97698.1 - 9.3e-45 152.4 0.1 1.5e-44 151.7 0.1 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KFO97698.1 - 3.1e-18 65.4 0.0 6.2e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Citrate_bind PF16114.5 KFO97698.1 - 0.07 12.6 0.0 0.32 10.5 0.0 1.9 2 0 0 2 2 2 0 ATP citrate lyase citrate-binding Peptidase_M13_N PF05649.13 KFO97699.1 - 9.1e-111 371.2 1.4 1.2e-110 370.8 1.4 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFO97699.1 - 4.1e-65 219.2 0.1 7.8e-65 218.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M13 DUF4589 PF15252.6 KFO97701.1 - 2.8e-78 263.3 4.8 3.1e-78 263.2 4.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4589) BUD22 PF09073.10 KFO97702.1 - 1.3e-11 44.6 58.4 1.5e-09 37.7 12.1 3.0 1 1 2 3 3 3 2 BUD22 DUF2868 PF11067.8 KFO97702.1 - 0.39 10.2 2.6 0.67 9.4 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) TcdB_N PF12918.7 KFO97702.1 - 3.5 8.0 13.2 8.4 6.8 1.2 4.1 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain Lysyl_oxidase PF01186.17 KFO97703.1 - 1.9e-94 315.1 5.5 2.1e-94 315.0 5.5 1.0 1 0 0 1 1 1 1 Lysyl oxidase CARDB PF07705.11 KFO97703.1 - 0.0066 16.7 0.0 0.042 14.1 0.0 2.2 2 0 0 2 2 2 1 CARDB BsuPI PF12690.7 KFO97703.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Intracellular proteinase inhibitor zf-C2HC_2 PF13913.6 KFO97704.1 - 4.5e-19 67.9 10.1 4.2e-11 42.5 0.9 2.8 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 KFO97704.1 - 0.001 19.7 5.6 0.68 10.9 0.3 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFO97704.1 - 0.0016 18.8 3.4 0.19 12.2 0.1 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type c-SKI_SMAD_bind PF08782.10 KFO97704.1 - 0.0038 17.4 0.8 0.01 16.0 0.0 1.9 1 1 1 2 2 2 1 c-SKI Smad4 binding domain zinc_ribbon_4 PF13717.6 KFO97704.1 - 0.014 15.3 0.1 4.4 7.3 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DUF2318 PF10080.9 KFO97704.1 - 0.022 14.9 0.6 0.82 9.8 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Rad50_zn_hook PF04423.14 KFO97704.1 - 0.035 14.0 0.2 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 Rad50 zinc hook motif Sgf11 PF08209.11 KFO97704.1 - 0.041 13.4 0.8 1.4 8.6 0.1 2.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) ADK_lid PF05191.14 KFO97704.1 - 0.046 13.7 0.5 9 6.4 0.0 2.8 2 1 0 2 2 2 0 Adenylate kinase, active site lid Vps36-NZF-N PF16988.5 KFO97704.1 - 0.11 11.9 1.8 0.61 9.5 0.1 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF2256 PF10013.9 KFO97704.1 - 0.12 12.5 1.1 8.9 6.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-CCHC PF00098.23 KFO97704.1 - 0.13 12.4 4.5 3.5 7.9 0.5 2.6 2 0 0 2 2 2 0 Zinc knuckle zf_C2H2_13 PF18508.1 KFO97704.1 - 0.24 11.0 3.3 2.2 7.9 0.4 2.3 2 0 0 2 2 2 0 Zinc finger domain zf-C2H2 PF00096.26 KFO97705.1 - 6.6e-08 32.6 14.2 0.13 12.7 0.0 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO97705.1 - 1.4e-05 25.5 13.9 0.11 13.3 0.1 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFO97705.1 - 0.00044 20.5 0.0 0.00044 20.5 0.0 3.3 4 0 0 4 4 4 1 Zinc-finger double domain Zn-C2H2_12 PF18112.1 KFO97705.1 - 0.005 17.3 0.0 0.66 10.5 0.0 2.6 2 0 0 2 2 2 1 Autophagy receptor zinc finger-C2H2 domain DUF4764 PF15961.5 KFO97705.1 - 0.007 15.1 0.3 0.0087 14.8 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4764) zf-C2H2_11 PF16622.5 KFO97705.1 - 0.01 15.6 13.2 0.76 9.6 0.0 3.6 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 KFO97705.1 - 0.17 12.0 2.0 3 7.9 0.0 2.4 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_8 PF15909.5 KFO97705.1 - 0.21 11.9 3.2 3.2 8.1 0.3 2.4 1 1 3 4 4 4 0 C2H2-type zinc ribbon RVT_1 PF00078.27 KFO97706.1 - 2.4e-24 86.1 0.0 3.3e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 KFO97706.1 - 2.4e-11 43.3 1.7 4.2e-11 42.5 1.7 1.4 1 0 0 1 1 1 1 Reverse transcriptase thumb domain HATPase_c PF02518.26 KFO97707.1 - 3.9e-08 33.8 0.0 1.4e-07 32.0 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 PF10436.9 KFO97707.1 - 4e-08 33.2 0.0 5.5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Fasciclin PF02469.22 KFO97708.1 - 5.5e-105 346.7 0.1 3.8e-27 95.0 0.0 4.4 4 0 0 4 4 4 4 Fasciclin domain MTCP1 PF08991.10 KFO97708.1 - 0.37 11.1 1.1 0.74 10.1 1.1 1.5 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type Lig_chan PF00060.26 KFO97709.1 - 5.9e-43 146.3 0.3 9.8e-43 145.6 0.3 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFO97709.1 - 4.9e-40 136.3 0.0 8.4e-40 135.5 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFO97709.1 - 1.8e-26 93.0 0.0 3.2e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 KFO97709.1 - 1.7e-20 73.5 0.0 3.1e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Receptor family ligand binding region LRR_6 PF13516.6 KFO97710.1 - 7.6e-15 53.6 18.1 0.0019 18.1 0.2 8.5 9 0 0 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.7 KFO97710.1 - 5.1e-05 23.6 22.3 0.073 13.5 0.5 6.1 4 2 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFO97710.1 - 9.6e-05 22.1 17.7 0.0082 15.9 0.4 5.7 4 2 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 KFO97710.1 - 0.023 15.2 21.7 2 9.3 0.1 7.9 8 2 0 8 8 8 0 Leucine Rich Repeat DUF4632 PF15451.6 KFO97710.1 - 0.25 11.5 0.8 0.53 10.4 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) RHD_DNA_bind PF00554.22 KFO97711.1 - 9.6e-20 71.2 0.1 1e-19 71.1 0.1 1.0 1 0 0 1 1 1 1 Rel homology DNA-binding domain CLPTM1 PF05602.12 KFO97712.1 - 6.2e-129 430.8 0.4 7.2e-129 430.5 0.4 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Thiolase_N PF00108.23 KFO97713.1 - 1.7e-83 280.0 0.1 2.6e-83 279.4 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFO97713.1 - 1.2e-49 167.1 0.0 2.3e-49 166.1 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFO97713.1 - 5.7e-08 32.6 1.6 4.4e-07 29.7 0.4 2.7 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KFO97713.1 - 0.38 10.6 2.2 5.6 6.9 0.1 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 3HCDH_N PF02737.18 KFO97714.1 - 7.2e-57 192.2 1.2 1.4e-56 191.3 1.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 KFO97714.1 - 2.7e-36 125.2 0.1 4.3e-36 124.5 0.1 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 KFO97714.1 - 6.7e-26 90.7 1.3 1.2e-25 89.9 0.1 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 KFO97714.1 - 2.4e-25 89.8 0.1 5.7e-25 88.5 0.0 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Ras PF00071.22 KFO97716.1 - 5.5e-10 39.1 0.1 6e-10 39.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO97716.1 - 1.7e-07 31.5 0.0 1.8e-07 31.4 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KFO97716.1 - 0.016 14.6 0.0 0.016 14.6 0.0 1.0 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 KFO97716.1 - 0.016 14.9 0.0 0.019 14.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFO97716.1 - 0.045 13.3 0.0 0.045 13.3 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KFO97716.1 - 0.059 13.4 0.0 0.059 13.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFO97716.1 - 0.06 13.7 0.0 0.061 13.7 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 KFO97716.1 - 0.068 12.6 0.1 0.07 12.6 0.1 1.0 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KFO97716.1 - 0.072 13.4 0.0 0.072 13.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 KFO97716.1 - 0.074 12.5 0.0 0.074 12.5 0.0 1.0 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_29 PF13555.6 KFO97716.1 - 0.084 12.6 0.2 0.086 12.6 0.2 1.2 1 1 0 1 1 1 0 P-loop containing region of AAA domain Pox_A32 PF04665.12 KFO97716.1 - 0.1 12.1 0.1 0.1 12.1 0.1 1.0 1 0 0 1 1 1 0 Poxvirus A32 protein NACHT PF05729.12 KFO97716.1 - 0.15 12.0 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 KFO97716.1 - 0.18 11.7 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase Kinesin PF00225.23 KFO97717.1 - 5.7e-119 396.9 0.0 5.7e-119 396.9 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFO97717.1 - 5.5e-28 97.8 0.5 2.6e-27 95.6 0.0 2.3 2 1 0 2 2 2 1 Microtubule binding PIF1 PF05970.14 KFO97717.1 - 0.00024 20.4 1.4 0.063 12.4 0.0 2.3 2 0 0 2 2 2 2 PIF1-like helicase Kinesin_assoc PF16183.5 KFO97717.1 - 0.015 15.5 10.2 0.015 15.5 10.2 2.1 2 1 1 3 3 3 0 Kinesin-associated AAA_16 PF13191.6 KFO97717.1 - 0.23 11.8 0.0 0.23 11.8 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 KFO97717.1 - 0.69 10.2 0.0 0.69 10.2 0.0 2.8 3 1 0 3 3 3 0 AAA domain MACPF PF01823.19 KFO97718.1 - 7.1e-08 32.8 0.0 1.1e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 MAC/Perforin domain DUF5639 PF18690.1 KFO97718.1 - 0.037 14.2 0.1 0.071 13.3 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5639) Adeno_E3_CR2 PF02439.15 KFO97718.1 - 0.36 10.6 0.0 0.36 10.6 0.0 1.7 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DTC PF18102.1 KFO97719.1 - 6.7e-58 194.6 0.0 1e-57 194.0 0.0 1.3 1 0 0 1 1 1 1 Deltex C-terminal domain zf-RING_UBOX PF13445.6 KFO97719.1 - 1.7e-08 34.3 1.0 4.7e-08 32.9 1.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFO97719.1 - 5.1e-08 32.7 1.4 1.1e-07 31.6 1.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFO97719.1 - 7.2e-08 32.6 1.6 2.8e-07 30.8 1.6 2.0 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFO97719.1 - 2.5e-06 27.7 0.8 2.5e-06 27.7 0.8 1.8 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFO97719.1 - 8.9e-06 25.6 1.4 2e-05 24.4 1.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFO97719.1 - 4e-05 23.4 2.5 0.015 15.1 0.8 2.8 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFO97719.1 - 7.4e-05 22.4 4.6 0.011 15.4 0.7 2.7 2 0 0 2 2 2 2 RING-like zinc finger zf-ANAPC11 PF12861.7 KFO97719.1 - 7.4e-05 22.7 0.5 0.00015 21.7 0.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KFO97719.1 - 0.0034 17.5 3.0 0.013 15.7 0.9 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 KFO97719.1 - 0.0063 16.6 0.1 0.018 15.1 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding RING-finger Zn_ribbon_17 PF17120.5 KFO97719.1 - 0.015 14.9 0.3 0.015 14.9 0.3 1.8 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type Trm112p PF03966.16 KFO97719.1 - 0.04 14.5 0.2 0.082 13.5 0.2 1.5 1 0 0 1 1 1 0 Trm112p-like protein FANCL_C PF11793.8 KFO97719.1 - 0.059 13.5 1.4 0.19 11.9 1.4 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 KFO97719.1 - 0.077 12.9 2.6 0.35 10.8 2.7 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 PHD PF00628.29 KFO97719.1 - 0.083 12.8 0.8 0.083 12.8 0.8 2.1 2 0 0 2 2 2 0 PHD-finger zf-RING_4 PF14570.6 KFO97719.1 - 0.089 12.6 1.3 0.16 11.8 0.2 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KFO97719.1 - 0.29 11.0 3.3 3.6 7.5 0.4 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) ADK_lid PF05191.14 KFO97719.1 - 0.3 11.1 2.3 3.6 7.6 0.2 3.0 2 0 0 2 2 2 0 Adenylate kinase, active site lid CNTF PF01110.17 KFO97720.1 - 1.9e-89 298.2 0.3 2.2e-89 298.0 0.3 1.0 1 0 0 1 1 1 1 Ciliary neurotrophic factor DUF2157 PF09925.9 KFO97720.1 - 0.079 12.7 0.1 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Thioredoxin PF00085.20 KFO97721.1 - 1.2e-10 41.3 0.0 2.2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin DUF5020 PF16412.5 KFO97721.1 - 0.084 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5020) Med19 PF10278.9 KFO97722.1 - 2.1e-78 262.3 12.9 2.4e-78 262.1 12.9 1.0 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 Connexin PF00029.19 KFO97722.1 - 0.0049 16.7 0.2 0.0063 16.3 0.2 1.1 1 0 0 1 1 1 1 Connexin Zip PF02535.22 KFO97722.1 - 0.032 13.4 1.8 0.036 13.3 1.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RNA_polI_A34 PF08208.11 KFO97722.1 - 0.49 10.5 23.8 0.76 9.8 23.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Tim54 PF11711.8 KFO97722.1 - 3.6 6.3 11.6 4.6 5.9 11.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.12 KFO97722.1 - 5 6.9 11.0 6.5 6.5 11.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DHHC PF01529.20 KFO97723.1 - 1.5e-36 125.4 7.8 1.5e-36 125.4 7.8 1.9 2 1 1 3 3 3 1 DHHC palmitoyltransferase DUF4179 PF13786.6 KFO97723.1 - 0.17 12.3 0.0 0.54 10.8 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) CLP1_P PF16575.5 KFO97724.1 - 2.3e-77 259.1 0.0 3.3e-77 258.6 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 KFO97724.1 - 1.8e-33 114.6 0.2 3.4e-33 113.7 0.2 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 KFO97724.1 - 1.7e-30 105.9 0.0 2.6e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MMR_HSR1 PF01926.23 KFO97724.1 - 0.0057 16.7 0.0 0.013 15.6 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KFO97724.1 - 0.0084 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein TniB PF05621.11 KFO97724.1 - 0.054 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_18 PF13238.6 KFO97724.1 - 0.061 13.9 0.1 0.55 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KFO97724.1 - 0.08 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KFO97724.1 - 0.096 12.7 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 KFO97724.1 - 0.12 12.7 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 KFO97724.1 - 0.14 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Yippee-Mis18 PF03226.14 KFO97725.1 - 9.6e-14 51.5 0.3 1.1e-13 51.3 0.3 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly ATPgrasp_YheCD PF14398.6 KFO97725.1 - 0.0065 15.8 0.0 0.009 15.3 0.0 1.2 1 0 0 1 1 1 1 YheC/D like ATP-grasp RIG-I_C-RD PF11648.8 KFO97725.1 - 0.031 14.5 0.3 0.05 13.8 0.3 1.4 1 1 0 1 1 1 0 C-terminal domain of RIG-I AlcCBM31 PF11606.8 KFO97725.1 - 0.047 13.9 0.2 1.3 9.2 0.0 2.1 1 1 1 2 2 2 0 Family 31 carbohydrate binding protein zf-Tim10_DDP PF02953.15 KFO97726.1 - 2.8e-17 62.1 0.6 3.8e-17 61.7 0.6 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger P2X_receptor PF00864.19 KFO97727.1 - 2.5e-52 178.2 0.0 2.7e-52 178.1 0.0 1.0 1 0 0 1 1 1 1 ATP P2X receptor WAP PF00095.21 KFO97727.1 - 7.4 7.0 7.7 0.46 10.9 0.9 2.2 2 1 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' POB3_N PF17292.2 KFO97728.1 - 1.8e-28 98.8 0.3 5.2e-25 87.7 0.1 2.7 2 0 0 2 2 2 2 POB3-like N-terminal PH domain SSrecog PF03531.14 KFO97728.1 - 6.5e-28 96.4 0.0 1.5e-27 95.3 0.0 1.7 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 KFO97728.1 - 1.1e-27 96.2 0.1 8e-27 93.5 0.1 2.4 2 0 0 2 2 2 1 Histone chaperone Rttp106-like HMG_box PF00505.19 KFO97728.1 - 5e-24 84.5 4.1 5e-24 84.5 4.1 2.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFO97728.1 - 9.1e-13 48.6 3.3 9.1e-13 48.6 3.3 2.4 2 0 0 2 2 2 1 HMG-box domain 7tm_1 PF00001.21 KFO97729.1 - 1.7e-35 122.6 7.3 1e-21 77.5 1.8 2.0 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFO97729.1 - 0.00099 18.9 0.5 0.012 15.4 0.4 2.0 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srv PF10323.9 KFO97729.1 - 0.32 10.3 3.0 0.45 9.8 0.4 1.9 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv INCENP_ARK-bind PF03941.15 KFO97730.1 - 1.5e-18 66.5 0.4 1.5e-18 66.5 0.4 2.0 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Ndc1_Nup PF09531.10 KFO97730.1 - 1.7 7.2 4.4 1.8 7.2 4.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup INCENP_ARK-bind PF03941.15 KFO97731.1 - 2.2e-19 69.1 1.5 3.1e-19 68.6 0.1 2.1 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Uteroglobin PF01099.17 KFO97732.1 - 2.5e-09 37.3 0.0 2.6e-09 37.3 0.0 1.0 1 0 0 1 1 1 1 Uteroglobin family EFG_IV PF03764.18 KFO97732.1 - 0.15 11.9 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Elongation factor G, domain IV SHIPPO-rpt PF07004.12 KFO97733.1 - 2e-05 25.2 24.9 0.0083 17.0 2.4 5.5 5 1 0 5 5 5 4 Sperm-tail PG-rich repeat Ric8 PF10165.9 KFO97735.1 - 2e-133 445.8 1.4 5.6e-133 444.3 0.4 1.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor synembryn SIR2 PF02146.17 KFO97736.1 - 3.8e-54 183.3 0.0 4.9e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Rad50_zn_hook PF04423.14 KFO97736.1 - 1.2 9.1 3.7 12 5.8 0.1 2.4 1 1 1 2 2 2 0 Rad50 zinc hook motif Glyco_hydro_65m PF03632.15 KFO97737.1 - 1.1e-57 195.7 0.0 6e-50 170.2 0.6 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain CD225 PF04505.12 KFO97738.1 - 1.4e-23 82.8 0.1 1.9e-23 82.3 0.1 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF4190 PF13828.6 KFO97738.1 - 0.16 11.8 2.1 0.38 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) CHGN PF05679.16 KFO97739.1 - 1.6e-24 86.7 0.0 4.5e-24 85.2 0.0 1.7 1 1 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 KFO97739.1 - 1.4e-07 31.1 1.5 2.7e-07 30.1 1.5 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase PA14 PF07691.12 KFO97739.1 - 4.9e-05 23.2 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Thioredoxin_8 PF13905.6 KFO97739.1 - 0.041 14.2 0.0 0.15 12.4 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin-like Arm PF00514.23 KFO97740.1 - 4.1e-20 71.1 1.1 3.4e-06 26.9 0.0 6.0 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KFO97740.1 - 0.0014 19.1 0.4 0.15 12.6 0.0 3.8 4 0 0 4 4 4 1 HEAT-like repeat Atx10homo_assoc PF09759.9 KFO97740.1 - 0.0034 17.4 2.4 0.13 12.2 0.1 3.5 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 KFO97740.1 - 0.04 14.3 0.0 0.29 11.6 0.0 2.5 1 1 0 1 1 1 0 HEAT repeats V-ATPase_H_C PF11698.8 KFO97740.1 - 0.052 13.7 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 V-ATPase subunit H Adaptin_N PF01602.20 KFO97740.1 - 0.092 11.3 0.1 0.24 9.9 0.0 1.6 2 0 0 2 2 2 0 Adaptin N terminal region L31 PF09784.9 KFO97740.1 - 0.14 12.6 0.1 3.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 Ribonuc_2-5A PF06479.12 KFO97740.1 - 0.36 11.0 1.8 1.6 8.9 0.1 2.7 3 0 0 3 3 3 0 Ribonuclease 2-5A TIR PF01582.20 KFO97741.1 - 6e-18 65.3 0.0 8.3e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 KFO97741.1 - 2.3e-08 34.7 0.0 4e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 TIR domain Ig_3 PF13927.6 KFO97741.1 - 3.5e-08 33.9 0.1 6.9e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFO97741.1 - 0.017 15.4 0.1 0.05 13.9 0.1 1.8 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFO97741.1 - 0.053 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin I-set domain ig PF00047.25 KFO97741.1 - 0.085 13.0 0.8 0.22 11.7 0.8 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Anoctamin PF04547.12 KFO97742.1 - 9.5e-136 453.2 17.5 1.2e-135 452.8 17.5 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KFO97742.1 - 1.6e-12 47.6 1.0 5.3e-09 36.1 0.0 2.4 2 0 0 2 2 2 2 Dimerisation domain of Ca+-activated chloride-channel, anoctamin CitMHS PF03600.16 KFO97742.1 - 0.066 12.4 0.1 0.13 11.5 0.1 1.5 1 1 0 1 1 1 0 Citrate transporter PSS PF03034.15 KFO97743.1 - 3.2e-112 374.7 15.9 4.7e-112 374.2 15.9 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase HemY_N PF07219.13 KFO97743.1 - 0.007 16.6 0.1 0.027 14.7 0.1 2.0 1 0 0 1 1 1 1 HemY protein N-terminus LapA_dom PF06305.11 KFO97743.1 - 0.059 13.2 0.0 0.26 11.1 0.0 2.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF3382 PF11862.8 KFO97743.1 - 4.1 7.8 7.2 2.5 8.5 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3382) C2 PF00168.30 KFO97744.1 - 3.6e-20 72.2 0.0 2.1e-14 53.6 0.0 2.4 2 0 0 2 2 2 2 C2 domain AAA_12 PF13087.6 KFO97745.1 - 2.3e-51 174.3 0.0 3.4e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFO97745.1 - 9.1e-46 156.8 3.9 9.8e-24 84.5 0.0 3.3 4 0 0 4 4 3 2 AAA domain AAA_30 PF13604.6 KFO97745.1 - 6.4e-13 48.9 0.0 1.3e-10 41.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KFO97745.1 - 6.4e-11 42.8 0.0 2.3e-10 41.0 0.0 2.0 2 1 0 2 2 1 1 AAA domain R3H PF01424.22 KFO97745.1 - 1.4e-09 37.8 0.1 4.3e-09 36.2 0.1 1.9 1 0 0 1 1 1 1 R3H domain Helicase_RecD PF05127.14 KFO97745.1 - 8.9e-09 35.4 0.0 0.0068 16.3 0.0 3.7 4 0 0 4 4 3 2 Helicase zf-AN1 PF01428.16 KFO97745.1 - 1.9e-08 34.3 7.9 4.7e-08 33.1 7.9 1.7 1 0 0 1 1 1 1 AN1-like Zinc finger Viral_helicase1 PF01443.18 KFO97745.1 - 2.4e-07 30.7 0.7 0.23 11.1 0.2 3.5 3 1 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KFO97745.1 - 0.0006 20.1 0.0 0.0023 18.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 KFO97745.1 - 0.0015 18.5 0.1 0.0038 17.2 0.1 1.7 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_16 PF13191.6 KFO97745.1 - 0.0016 18.9 0.0 0.0066 16.8 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KFO97745.1 - 0.002 17.7 0.0 0.016 14.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KFO97745.1 - 0.0023 18.0 0.0 0.021 14.8 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFO97745.1 - 0.0034 17.2 0.0 0.014 15.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase IstB_IS21 PF01695.17 KFO97745.1 - 0.0044 16.8 0.0 0.0087 15.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein UvrD-helicase PF00580.21 KFO97745.1 - 0.0052 16.3 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 KFO97745.1 - 0.0063 15.8 0.1 0.086 12.1 0.0 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 KFO97745.1 - 0.0091 15.2 0.0 0.051 12.7 0.0 1.9 2 0 0 2 2 2 1 PIF1-like helicase T2SSE PF00437.20 KFO97745.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 KFO97745.1 - 0.019 15.4 0.0 0.042 14.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 KFO97745.1 - 0.033 14.0 0.1 0.075 12.9 0.1 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PhoH PF02562.16 KFO97745.1 - 0.045 13.2 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Herpes_ori_bp PF02399.15 KFO97745.1 - 0.045 11.8 0.0 0.065 11.3 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein Zot PF05707.12 KFO97745.1 - 0.05 13.2 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_33 PF13671.6 KFO97745.1 - 0.054 13.6 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 KFO97745.1 - 0.088 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 RL PF17797.1 KFO97745.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 RL domain cobW PF02492.19 KFO97745.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Ribosomal_L21p PF00829.21 KFO97746.1 - 2.6e-22 79.0 0.0 5.6e-22 77.9 0.0 1.5 2 0 0 2 2 2 1 Ribosomal prokaryotic L21 protein Ras PF00071.22 KFO97747.1 - 1.1e-25 90.1 0.0 1.2e-25 90.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO97747.1 - 0.00025 21.2 0.0 0.00042 20.5 0.0 1.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Glyco_hydro_31 PF01055.26 KFO97748.1 - 3.1e-26 92.6 0.0 3.9e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DnaJ PF00226.31 KFO97749.1 - 7.9e-15 54.7 0.3 1.9e-14 53.5 0.3 1.7 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.22 KFO97749.1 - 8.9e-06 25.4 0.0 1.7e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFO97749.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SpoVR PF04293.13 KFO97749.1 - 0.3 9.7 6.9 0.45 9.1 6.9 1.2 1 0 0 1 1 1 0 SpoVR like protein FUSC PF04632.12 KFO97749.1 - 8.2 4.8 6.5 13 4.2 6.5 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family BORG_CEP PF14957.6 KFO97750.1 - 3.5e-05 24.9 1.4 7e-05 24.0 1.4 1.6 1 1 0 1 1 1 1 Cdc42 effector DUF4739 PF15893.5 KFO97750.1 - 0.099 12.2 1.0 0.27 10.7 0.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4739) GFRP PF06399.13 KFO97751.1 - 4.7e-34 116.1 0.1 5.1e-34 116.0 0.1 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I feedback regulatory protein (GFRP) TPR_11 PF13414.6 KFO97752.1 - 0.0027 17.3 1.1 0.011 15.4 0.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_19 PF14559.6 KFO97752.1 - 0.014 15.9 1.0 21 5.7 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat RPW8 PF05659.11 KFO97752.1 - 0.024 14.3 0.4 0.062 13.0 0.4 1.6 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TPR_17 PF13431.6 KFO97752.1 - 0.047 14.1 2.3 0.58 10.7 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat FliT PF05400.13 KFO97752.1 - 2 9.3 9.7 8.9 7.2 1.1 3.5 3 0 0 3 3 3 0 Flagellar protein FliT Med4 PF10018.9 KFO97752.1 - 7.2 6.2 8.0 1.8 8.2 0.9 2.8 2 1 1 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 Rad51 PF08423.11 KFO97753.1 - 1.5e-129 430.7 0.0 1.9e-129 430.4 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KFO97753.1 - 4e-11 42.9 0.0 5.7e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KFO97753.1 - 2.4e-09 37.1 0.1 3.7e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 KFO97753.1 - 2.7e-09 37.5 0.3 1e-08 35.7 0.4 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 KFO97753.1 - 7.4e-05 22.2 1.5 0.00041 19.8 0.9 2.3 2 1 0 2 2 2 1 KaiC HHH PF00633.23 KFO97753.1 - 0.0067 16.2 0.2 0.015 15.1 0.2 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HhH-GPD PF00730.25 KFO97753.1 - 0.013 15.9 0.0 0.12 12.9 0.0 2.1 1 1 1 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein AAA_22 PF13401.6 KFO97753.1 - 0.019 15.3 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFO97753.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ssDNA_TraI_N PF18272.1 KFO97753.1 - 0.086 12.9 0.2 0.18 11.8 0.2 1.5 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain DUF1953 PF09196.10 KFO97755.1 - 0.011 15.5 0.1 0.026 14.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1953) PseudoU_synth_2 PF00849.22 KFO97756.1 - 6.4e-30 104.4 0.0 9.9e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase c-SKI_SMAD_bind PF08782.10 KFO97756.1 - 0.083 13.1 0.1 0.28 11.4 0.0 1.8 2 0 0 2 2 2 0 c-SKI Smad4 binding domain PCMT PF01135.19 KFO97757.1 - 1.2e-80 270.2 0.0 1.4e-80 270.0 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KFO97757.1 - 5.9e-07 30.1 0.0 1e-06 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFO97757.1 - 8.1e-07 29.0 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFO97757.1 - 2.3e-05 24.9 0.0 4.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 KFO97757.1 - 0.0002 21.1 0.0 0.00024 20.9 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Ubie_methyltran PF01209.18 KFO97757.1 - 0.00025 20.5 0.0 0.00035 20.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KFO97757.1 - 0.0075 15.8 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KFO97757.1 - 0.045 13.7 0.0 0.066 13.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KFO97757.1 - 0.088 12.6 0.0 0.16 11.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 KFO97757.1 - 0.19 11.7 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KFO97757.1 - 0.19 11.1 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CCDC32 PF14989.6 KFO97758.1 - 4.1e-58 195.7 0.1 5e-58 195.4 0.1 1.0 1 0 0 1 1 1 1 Coiled-coil domain containing 32 BAH PF01426.18 KFO97759.1 - 7.2e-15 54.9 0.1 2.8e-14 53.0 0.1 1.9 1 1 0 1 1 1 1 BAH domain Acyl-CoA_dh_1 PF00441.24 KFO97760.1 - 4.3e-38 130.9 0.1 6.4e-38 130.3 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFO97760.1 - 8e-35 119.9 0.0 1.4e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFO97760.1 - 2.9e-26 91.5 0.0 4.9e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFO97760.1 - 1.3e-09 38.4 0.0 2.3e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Phage_GP20 PF06810.11 KFO97761.1 - 0.0069 16.2 4.9 0.0069 16.2 4.9 2.3 1 1 0 2 2 2 1 Phage minor structural protein GP20 TPR_MLP1_2 PF07926.12 KFO97761.1 - 0.029 14.4 4.4 0.029 14.4 4.4 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DivIC PF04977.15 KFO97761.1 - 0.044 13.5 2.3 0.044 13.5 2.3 3.4 2 2 1 3 3 3 0 Septum formation initiator KfrA_N PF11740.8 KFO97761.1 - 0.2 12.3 13.8 0.3 11.8 1.5 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term EIAV_Rev PF11129.8 KFO97761.1 - 0.23 11.7 7.2 0.82 9.9 0.3 2.1 1 1 1 2 2 2 0 Rev protein of equine infectious anaemia virus RasGAP_C PF03836.15 KFO97761.1 - 0.25 11.5 10.7 2.1 8.5 9.4 2.3 1 1 0 1 1 1 0 RasGAP C-terminus DUF1043 PF06295.12 KFO97761.1 - 0.56 10.2 16.4 0.79 9.7 5.3 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1043) Csm1_N PF18504.1 KFO97761.1 - 1.1 9.6 14.1 2.8 8.3 5.8 2.7 2 0 0 2 2 2 0 Csm1 N-terminal domain CASP_C PF08172.12 KFO97761.1 - 1.1 8.5 10.8 0.25 10.6 0.6 2.1 2 0 0 2 2 2 0 CASP C terminal Seryl_tRNA_N PF02403.22 KFO97761.1 - 1.4 9.2 19.6 3.5 7.9 4.7 3.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BST2 PF16716.5 KFO97761.1 - 1.4 9.6 23.4 5.2 7.7 3.3 2.6 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 FlaC_arch PF05377.11 KFO97761.1 - 2.4 8.6 5.7 1.6 9.2 1.6 2.8 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4200 PF13863.6 KFO97761.1 - 2.5 8.5 23.2 0.92 9.9 4.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF948 PF06103.11 KFO97761.1 - 4 7.7 6.1 2.7 8.3 0.5 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) CP12 PF02672.15 KFO97761.1 - 5.7 7.8 14.8 0.39 11.5 6.4 2.7 2 1 0 2 2 2 0 CP12 domain YabA PF06156.13 KFO97761.1 - 9.8 6.9 17.3 2.1 9.0 6.7 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Patched PF02460.18 KFO97762.1 - 2.4 6.1 30.9 1.6 6.7 11.5 2.5 2 0 0 2 2 2 0 Patched family Sterol-sensing PF12349.8 KFO97762.1 - 3.3 7.6 32.1 0.019 14.8 14.0 2.6 2 0 0 2 2 2 0 Sterol-sensing domain of SREBP cleavage-activation DUF4594 PF15266.6 KFO97763.1 - 7.3e-25 88.4 10.6 7.3e-25 88.4 10.6 2.1 1 1 0 2 2 2 1 Domain of unknown function (DUF4594) PI-PLC-X PF00388.19 KFO97764.1 - 9e-59 197.2 0.1 2.4e-58 195.8 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFO97764.1 - 7.3e-40 135.9 1.7 1.7e-39 134.7 1.7 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain PH_14 PF17787.1 KFO97764.1 - 1e-39 135.4 0.0 2e-39 134.5 0.0 1.5 1 0 0 1 1 1 1 PH domain EF-hand_like PF09279.11 KFO97764.1 - 1.8e-08 34.7 0.0 5.6e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 KFO97764.1 - 2.9e-07 30.7 0.0 6e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.25 KFO97765.1 - 9e-66 221.9 0.0 1.1e-65 221.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO97765.1 - 6.2e-44 150.2 0.0 8.8e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KFO97765.1 - 7.2e-16 58.3 0.1 1.6e-15 57.2 0.1 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KFO97765.1 - 2.6e-06 27.0 0.0 3.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFO97765.1 - 0.00018 20.4 0.0 0.0003 19.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase ORC6 PF05460.13 KFO97765.1 - 0.11 11.7 4.5 0.34 10.1 4.5 1.8 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Kdo PF06293.14 KFO97765.1 - 0.16 11.3 0.1 0.26 10.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mad3_BUB1_I PF08311.12 KFO97766.1 - 5.5e-44 149.1 0.1 5.5e-44 149.1 0.1 1.9 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 KFO97766.1 - 3.6e-05 23.3 0.3 0.0001 21.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain MerR-DNA-bind PF09278.11 KFO97766.1 - 0.0032 18.0 4.9 0.011 16.3 4.9 1.9 1 0 0 1 1 1 1 MerR, DNA binding VSG_B PF13206.6 KFO97766.1 - 0.08 12.2 4.9 0.13 11.5 4.9 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain Nup88 PF10168.9 KFO97766.1 - 1.1 6.9 10.1 1.7 6.3 10.1 1.2 1 0 0 1 1 1 0 Nuclear pore component K_oxygenase PF13434.6 KFO97766.1 - 4.1 6.4 6.2 7.4 5.6 6.2 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) TetR_C_23 PF17931.1 KFO97766.1 - 4.3 7.5 6.0 18 5.5 0.0 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Cadherin PF00028.17 KFO97767.1 - 2.5e-16 59.9 0.5 9.7e-07 29.2 0.0 2.4 2 0 0 2 2 2 2 Cadherin domain Cadherin_3 PF16184.5 KFO97767.1 - 0.014 15.4 1.4 0.44 10.6 0.1 3.3 2 1 0 2 2 2 0 Cadherin-like Peptidase_M61_N PF17899.1 KFO97767.1 - 0.049 13.7 0.0 0.79 9.8 0.0 2.5 2 1 1 3 3 3 0 Peptidase M61 N-terminal domain Hormone_2 PF00123.20 KFO97768.1 - 3.9e-18 65.0 0.0 3.8e-12 45.9 0.0 2.4 2 0 0 2 2 2 2 Peptide hormone SAND PF01342.21 KFO97769.1 - 2.8e-26 91.0 0.2 8.6e-26 89.5 0.0 2.0 2 0 0 2 2 2 1 SAND domain zf-MYND PF01753.18 KFO97769.1 - 8.3e-10 38.6 16.4 8.3e-10 38.6 16.4 2.0 2 0 0 2 2 2 1 MYND finger DUF4858 PF16150.5 KFO97769.1 - 0.37 10.8 1.8 11 6.0 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4858) Transmemb_17 PF09799.9 KFO97770.1 - 1.2e-32 112.7 8.8 1.5e-32 112.4 8.8 1.1 1 0 0 1 1 1 1 Predicted membrane protein PTB PF08416.13 KFO97771.1 - 4.3e-47 159.6 3.2 8e-47 158.7 3.2 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SAM_3 PF18016.1 KFO97771.1 - 1.1e-25 89.3 0.1 2.3e-25 88.2 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 KFO97771.1 - 1.6e-10 40.4 0.1 4.7e-10 38.9 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFO97771.1 - 4.9e-08 32.7 0.0 1.1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PID PF00640.23 KFO97771.1 - 9.5e-06 25.7 2.4 1.5e-05 25.1 0.5 2.1 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) SH3_2 PF07653.17 KFO97771.1 - 1.8e-05 24.3 0.0 3.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFO97771.1 - 0.047 14.0 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain SAM_PNT PF02198.16 KFO97771.1 - 0.093 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain NdhM PF10664.9 KFO97771.1 - 0.29 11.4 1.2 0.83 9.9 0.2 2.2 2 0 0 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M TAL_FSA PF00923.19 KFO97772.1 - 3e-98 328.7 0.0 3.3e-98 328.6 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase DJ-1_PfpI PF01965.24 KFO97773.1 - 0.0037 17.1 0.0 0.0043 16.9 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KFO97773.1 - 0.023 14.4 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 ThiJ/PfpI family-like CEND1 PF15677.5 KFO97774.1 - 7.7e-46 156.3 13.0 8.6e-46 156.1 13.0 1.0 1 0 0 1 1 1 1 Cell cycle exit and neuronal differentiation protein 1 Alpha_GJ PF03229.13 KFO97774.1 - 0.49 11.0 5.0 0.34 11.5 3.6 1.5 1 1 1 2 2 2 0 Alphavirus glycoprotein J NACHT PF05729.12 KFO97775.1 - 3.4e-34 118.1 0.0 8.3e-34 116.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain NLRC4_HD2 PF17776.1 KFO97775.1 - 1.6e-19 70.7 0.2 4.1e-19 69.4 0.2 1.8 1 0 0 1 1 1 1 NLRC4 helical domain HD2 NOD2_WH PF17779.1 KFO97775.1 - 3.8e-15 55.9 0.0 1e-14 54.6 0.0 1.8 1 0 0 1 1 1 1 NOD2 winged helix domain AAA_22 PF13401.6 KFO97775.1 - 0.00056 20.2 0.0 0.005 17.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFO97775.1 - 0.00071 20.0 0.0 0.0028 18.0 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KFO97775.1 - 0.0048 17.3 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFO97775.1 - 0.022 15.2 0.0 0.039 14.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KFO97775.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KFO97775.1 - 0.17 11.1 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TPR_2 PF07719.17 KFO97776.1 - 1.4e-07 31.1 1.4 0.0005 20.0 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat FKBP_C PF00254.28 KFO97776.1 - 0.0032 17.8 0.0 0.017 15.4 0.0 2.1 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.6 KFO97776.1 - 0.011 15.4 7.5 0.63 9.8 2.0 2.9 3 0 0 3 3 3 0 TPR repeat PaREP1 PF05942.11 KFO97776.1 - 0.021 14.7 0.4 0.051 13.5 0.1 1.7 2 0 0 2 2 2 0 Archaeal PaREP1/PaREP8 family TPR_8 PF13181.6 KFO97776.1 - 0.097 12.9 0.9 0.48 10.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFO97776.1 - 0.41 10.5 9.9 0.76 9.7 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat EF-hand_1 PF00036.32 KFO97777.1 - 1.8e-32 108.5 12.9 5.2e-10 38.1 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KFO97777.1 - 8.6e-27 90.8 5.3 1.7e-09 36.9 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 KFO97777.1 - 9.3e-26 90.1 7.9 6.2e-17 61.8 1.2 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFO97777.1 - 3.6e-23 81.2 11.0 1.5e-13 50.3 0.9 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KFO97777.1 - 1.8e-22 77.7 8.5 5e-09 35.2 0.1 4.0 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 KFO97777.1 - 2.5e-10 40.5 0.1 0.00031 21.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KFO97777.1 - 0.00015 22.1 0.1 0.01 16.2 0.0 2.2 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KFO97777.1 - 0.00032 20.8 0.4 0.014 15.6 0.7 2.8 2 1 1 3 3 3 2 Dockerin type I domain Caleosin PF05042.13 KFO97777.1 - 0.0015 18.5 0.0 0.35 10.8 0.0 2.5 2 1 1 3 3 3 1 Caleosin related protein EF-hand_4 PF12763.7 KFO97777.1 - 0.0018 18.2 4.8 0.0038 17.2 0.3 2.9 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand OST-HTH PF12872.7 KFO97777.1 - 0.0053 16.5 0.0 0.051 13.4 0.0 2.2 2 0 0 2 2 2 1 OST-HTH/LOTUS domain DIMCO_N PF16844.5 KFO97777.1 - 0.023 15.0 0.1 0.054 13.8 0.0 1.6 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal Prefoldin_3 PF13758.6 KFO97777.1 - 0.047 13.8 0.1 0.18 11.9 0.1 1.8 1 1 1 2 2 2 0 Prefoldin subunit EF-hand_11 PF08976.11 KFO97777.1 - 0.12 13.3 0.1 0.59 11.0 0.0 1.9 1 1 1 2 2 2 0 EF-hand domain Complex1_51K PF01512.17 KFO97779.1 - 8.1e-25 87.5 0.0 1e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KFO97779.1 - 2.3e-14 53.2 0.1 5.5e-14 52.0 0.0 1.7 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region DUF3568 PF12092.8 KFO97779.1 - 0.05 13.7 0.2 0.086 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) Mito_carr PF00153.27 KFO97780.1 - 0.0086 16.0 0.0 0.78 9.7 0.0 2.6 2 0 0 2 2 2 2 Mitochondrial carrier protein FAP PF07174.11 KFO97780.1 - 1 8.7 12.1 1.3 8.4 12.1 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Nup160 PF11715.8 KFO97782.1 - 3.3e-99 333.0 0.0 4.2e-99 332.6 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 RhoGEF PF00621.20 KFO97783.1 - 1.6e-18 67.6 0.0 2.1e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain GSHPx PF00255.19 KFO97784.1 - 2.5e-21 75.3 0.5 3.1e-21 75.0 0.5 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Ras PF00071.22 KFO97785.1 - 7.5e-10 38.6 0.0 8.5e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO97785.1 - 1e-08 35.4 0.0 1.1e-08 35.3 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 KFO97785.1 - 0.003 17.5 0.0 0.0035 17.3 0.0 1.1 1 0 0 1 1 1 1 NACHT domain TniB PF05621.11 KFO97785.1 - 0.019 14.4 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 KFO97785.1 - 0.037 13.9 0.0 0.037 13.9 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase Arf PF00025.21 KFO97785.1 - 0.043 13.3 0.0 0.043 13.3 0.0 1.0 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_16 PF13191.6 KFO97785.1 - 0.048 14.0 0.0 0.051 13.9 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Pox_A32 PF04665.12 KFO97785.1 - 0.053 13.0 0.0 0.053 13.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.6 KFO97785.1 - 0.086 13.1 0.0 0.09 13.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFO97785.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KFO97785.1 - 0.11 12.0 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KFO97785.1 - 0.13 12.0 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KFO97785.1 - 0.17 11.9 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRPRB PF09439.10 KFO97785.1 - 0.17 11.3 0.0 0.18 11.2 0.0 1.0 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 KFO97785.1 - 0.22 10.8 0.0 0.22 10.8 0.0 1.0 1 0 0 1 1 1 0 Septin DAP3 PF10236.9 KFO97785.1 - 0.28 10.3 0.0 0.28 10.3 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 UNC-93 PF05978.16 KFO97786.1 - 2.5e-06 27.3 4.0 5.5e-05 22.9 1.5 2.5 2 0 0 2 2 2 2 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 KFO97786.1 - 6.7e-05 21.9 0.4 0.00012 21.1 0.4 1.3 1 0 0 1 1 1 1 MFS_1 like family Aldedh PF00171.22 KFO97787.1 - 1.4e-79 267.8 0.0 1.7e-79 267.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family T-box PF00907.22 KFO97788.1 - 6.5e-80 267.7 0.0 7.5e-80 267.5 0.0 1.0 1 0 0 1 1 1 1 T-box 7tm_4 PF13853.6 KFO97789.1 - 2.4e-41 142.3 9.8 2.9e-41 142.0 9.8 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO97789.1 - 7.7e-22 77.9 16.1 1e-21 77.4 16.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Stevor PF17410.2 KFO97789.1 - 0.019 14.5 1.1 0.026 14.1 1.1 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame 7tm_4 PF13853.6 KFO97791.1 - 2.8e-45 155.2 17.5 3.3e-45 155.0 17.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO97791.1 - 1.4e-19 70.5 19.2 2.1e-19 69.9 19.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SLC3A2_N PF16028.5 KFO97791.1 - 0.2 11.3 0.8 0.55 9.8 0.6 1.8 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus XPG_N PF00752.17 KFO97792.1 - 1.5e-36 124.9 0.0 4e-36 123.5 0.0 1.8 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 KFO97792.1 - 3e-31 107.6 0.0 9.3e-31 106.1 0.0 1.9 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 KFO97792.1 - 3.7e-07 30.6 0.0 2.2e-06 28.2 0.0 2.2 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.16 KFO97792.1 - 0.022 14.6 0.0 0.071 13.0 0.0 1.8 1 1 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain HHH_5 PF14520.6 KFO97792.1 - 0.045 14.4 0.0 0.12 13.0 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain Ost5 PF05251.12 KFO97793.1 - 2.4e-29 101.4 6.1 2.7e-29 101.2 6.1 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 DUF3810 PF12725.7 KFO97793.1 - 1.9 7.8 4.7 1.9 7.8 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) MRF_C2 PF13888.6 KFO97794.1 - 8.5e-45 152.0 0.1 1.5e-44 151.2 0.1 1.4 1 0 0 1 1 1 1 Myelin gene regulatory factor C-terminal domain 2 NDT80_PhoG PF05224.12 KFO97794.1 - 8.5e-28 97.8 0.5 6.7e-27 94.9 0.5 2.2 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family MRF_C1 PF13887.6 KFO97794.1 - 8.8e-23 79.2 1.0 1.5e-22 78.5 1.0 1.4 1 0 0 1 1 1 1 Myelin gene regulatory factor -C-terminal domain 1 Peptidase_S74 PF13884.6 KFO97794.1 - 1.4e-15 57.4 0.1 2.6e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 Chaperone of endosialidase Lipase_3 PF01764.25 KFO97795.1 - 5.7e-10 39.2 0.0 1.2e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) ELP6 PF09807.9 KFO97796.1 - 3.1e-101 338.0 2.2 3.4e-101 337.9 2.2 1.0 1 0 0 1 1 1 1 Elongation complex protein 6 FOXO_KIX_bdg PF16675.5 KFO97797.1 - 7.7e-30 103.0 2.7 7.7e-30 103.0 2.7 3.0 3 0 0 3 3 3 1 KIX-binding domain of forkhead box O, CR2 FOXO-TAD PF16676.5 KFO97797.1 - 6.5e-21 74.5 8.6 1.4e-20 73.4 8.6 1.6 1 0 0 1 1 1 1 Transactivation domain of FOXO protein family Forkhead PF00250.18 KFO97797.1 - 1e-08 35.3 0.3 2.1e-08 34.3 0.3 1.6 1 0 0 1 1 1 1 Forkhead domain COG6 PF06419.11 KFO97798.1 - 3.8e-210 699.3 12.1 4.3e-210 699.1 12.1 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 YabA PF06156.13 KFO97798.1 - 0.0024 18.5 1.2 0.011 16.4 1.2 2.2 1 0 0 1 1 1 1 Initiation control protein YabA Sec34 PF04136.15 KFO97798.1 - 0.0039 17.1 1.8 0.012 15.5 1.8 1.9 1 0 0 1 1 1 1 Sec34-like family KASH_CCD PF14662.6 KFO97798.1 - 0.0079 16.1 4.9 0.02 14.7 4.9 1.7 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Jnk-SapK_ap_N PF09744.9 KFO97798.1 - 0.014 15.6 3.4 0.047 13.9 3.4 2.0 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 SOGA PF11365.8 KFO97798.1 - 0.015 16.4 4.4 0.02 16.0 1.9 2.5 2 0 0 2 2 2 0 Protein SOGA DUF812 PF05667.11 KFO97798.1 - 0.024 13.5 6.1 0.016 14.1 3.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DUF4201 PF13870.6 KFO97798.1 - 0.026 14.3 3.6 0.075 12.8 3.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF4795 PF16043.5 KFO97798.1 - 0.028 14.0 3.2 0.1 12.2 3.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Takusan PF04822.13 KFO97798.1 - 0.036 14.0 2.3 0.058 13.3 0.6 2.3 2 0 0 2 2 2 0 Takusan DUF1043 PF06295.12 KFO97798.1 - 0.54 10.3 4.5 0.51 10.3 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF1664 PF07889.12 KFO97798.1 - 1 9.4 4.2 1.3 9.0 1.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) GLTSCR1 PF15249.6 KFO97798.1 - 1.2 9.6 4.1 1.3 9.5 1.6 2.2 1 1 1 2 2 2 0 Conserved region of unknown function on GLTSCR protein Prefoldin_2 PF01920.20 KFO97798.1 - 1.5 8.8 9.5 1.2 9.2 1.5 3.0 2 1 1 3 3 3 0 Prefoldin subunit TSNAXIP1_N PF15739.5 KFO97798.1 - 1.9 8.9 10.6 2.3 8.6 4.3 3.3 3 0 0 3 3 3 0 Translin-associated factor X-interacting N-terminus OmpH PF03938.14 KFO97798.1 - 5.3 7.4 9.8 4.2 7.7 7.6 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Mod_r PF07200.13 KFO97798.1 - 5.8 7.0 15.0 6.3 6.9 5.9 2.9 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Yae1_N PF09811.9 KFO97799.1 - 7.7e-18 63.9 63.5 1.8e+04 -28.3 63.5 6.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal L_HMGIC_fpl PF10242.9 KFO97800.1 - 5.1e-30 105.0 3.3 5.7e-30 104.9 3.3 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein UPF0016 PF01169.19 KFO97800.1 - 0.18 12.2 4.1 0.075 13.4 1.4 1.8 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 IPTL-CTERM PF18203.1 KFO97800.1 - 6.5 6.8 7.9 1.5 8.8 1.8 2.4 2 0 0 2 2 2 0 IPTL-CTERM motif Calc_CGRP_IAPP PF00214.19 KFO97801.1 - 5.8e-28 97.7 0.1 6.6e-28 97.5 0.1 1.0 1 0 0 1 1 1 1 Calcitonin / CGRP / IAPP family OATP PF03137.20 KFO97802.1 - 3.9e-163 543.7 17.7 4.4e-163 543.5 17.7 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFO97802.1 - 9.2e-22 77.4 26.1 9.2e-20 70.9 9.5 2.9 3 0 0 3 3 3 2 Major Facilitator Superfamily Kazal_2 PF07648.15 KFO97802.1 - 2e-11 43.8 7.4 4.9e-11 42.6 7.4 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFO97802.1 - 0.0057 16.6 5.2 0.013 15.5 5.2 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain OATP PF03137.20 KFO97803.1 - 1.4e-173 578.1 20.7 1.6e-173 577.9 20.7 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFO97803.1 - 1.6e-21 76.6 20.7 2.8e-19 69.3 15.7 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.15 KFO97803.1 - 4.4e-11 42.7 9.3 1.5e-10 41.1 9.3 2.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFO97803.1 - 0.00089 19.2 7.6 0.002 18.1 7.6 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain OATP PF03137.20 KFO97804.1 - 1.6e-179 597.7 14.3 2.2e-179 597.3 14.3 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFO97804.1 - 8.5e-24 84.1 18.9 1.2e-19 70.5 2.2 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily Kazal_2 PF07648.15 KFO97804.1 - 1.1e-10 41.4 8.3 2.7e-10 40.2 8.3 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFO97804.1 - 9.5e-05 22.3 3.6 0.00024 21.1 3.6 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain SOAR PF16533.5 KFO97805.1 - 3.2e-43 145.8 2.9 3.2e-43 145.8 2.9 3.1 2 1 0 2 2 2 1 STIM1 Orai1-activating region Noelin-1 PF12308.8 KFO97805.1 - 2.1 8.4 5.8 1.9 8.5 0.5 2.7 1 1 1 2 2 2 0 Neurogenesis glycoprotein MitMem_reg PF13012.6 KFO97805.1 - 3.1 8.3 7.3 40 4.7 5.6 2.7 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function Ribosomal_S20p PF01649.18 KFO97805.1 - 3.1 8.5 7.6 1.1 9.9 0.4 2.9 2 2 0 2 2 2 0 Ribosomal protein S20 DUF2564 PF10819.8 KFO97805.1 - 8.7 6.8 13.2 17 5.9 3.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2564) Ribonuc_red_lgC PF02867.15 KFO97806.1 - 7.8e-168 559.3 0.0 3.4e-167 557.1 0.0 1.8 1 1 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KFO97806.1 - 2.2e-23 82.0 0.1 6.1e-23 80.6 0.1 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KFO97806.1 - 3.4e-07 30.7 0.0 8e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 ATP cone domain Gryzun-like PF12742.7 KFO97806.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking 7tm_4 PF13853.6 KFO97807.1 - 2.9e-108 361.8 22.5 3.3e-108 361.6 22.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO97807.1 - 2.3e-21 76.3 21.1 4e-21 75.5 21.1 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFO97807.1 - 2.4e-05 23.9 17.5 0.00019 20.9 17.3 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Globin PF00042.22 KFO97808.1 - 4e-29 101.4 0.0 6.1e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Globin Globin PF00042.22 KFO97809.1 - 1.3e-28 99.8 0.0 2.4e-28 98.9 0.0 1.4 2 0 0 2 2 2 1 Globin Globin PF00042.22 KFO97810.1 - 1e-28 100.1 0.0 2e-28 99.2 0.0 1.4 2 0 0 2 2 2 1 Globin 7tm_4 PF13853.6 KFO97811.1 - 2.3e-103 345.7 19.2 2.6e-103 345.6 19.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO97811.1 - 1.3e-22 80.4 14.9 1.8e-22 80.0 14.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFO97811.1 - 2.3e-09 37.0 9.7 2.6e-09 36.8 9.0 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFO97811.1 - 0.15 11.7 13.1 0.016 14.8 8.8 1.5 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Folate_rec PF03024.14 KFO97812.1 - 3.4e-63 212.6 26.0 4e-63 212.4 26.0 1.1 1 0 0 1 1 1 1 Folate receptor family Glyco_transf_8C PF08437.10 KFO97812.1 - 0.11 12.6 0.3 0.58 10.3 0.1 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 8 C-terminal Ribosomal_S17_N PF16205.5 KFO97813.1 - 6.9e-16 58.4 0.3 1.5e-15 57.3 0.3 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KFO97813.1 - 2e-09 37.4 0.0 3.7e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 UL21a PF17636.2 KFO97813.1 - 0.075 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Viral Unique Long protein 21a BAAT_C PF08840.11 KFO97814.1 - 1.2e-65 221.4 0.0 1.5e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Bile_Hydr_Trans PF04775.14 KFO97814.1 - 2.9e-39 134.0 0.0 4.1e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region DLH PF01738.18 KFO97814.1 - 7.7e-07 28.9 0.0 0.00012 21.8 0.0 3.0 1 1 1 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.13 KFO97814.1 - 4.7e-06 26.4 0.0 8.7e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KFO97814.1 - 0.00054 19.5 0.1 0.0072 15.8 0.0 2.5 2 1 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 KFO97814.1 - 0.00085 18.1 0.0 0.34 9.5 0.0 2.6 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 KFO97815.1 - 1.5e-73 247.2 0.0 1.7e-73 247.1 0.0 1.0 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 KFO97815.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.18 KFO97815.1 - 0.15 11.6 0.2 1.2 8.6 0.0 2.2 2 1 0 2 2 2 0 Dienelactone hydrolase family LRR_4 PF12799.7 KFO97816.1 - 2.5e-14 53.1 11.5 2.1e-05 24.8 0.0 3.7 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFO97816.1 - 2.9e-08 33.4 2.5 0.00013 21.6 0.1 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KFO97816.1 - 9.7e-08 31.7 10.2 0.002 17.8 4.1 3.7 3 2 1 4 4 4 3 Leucine rich repeat Glyco_hydro_49 PF03718.13 KFO97816.1 - 0.055 13.5 0.3 0.11 12.4 0.3 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 49 LRR_6 PF13516.6 KFO97816.1 - 0.61 10.3 5.1 6.3 7.1 0.4 4.0 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 KFO97816.1 - 1.3 9.9 14.1 47 5.1 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat ADH_N_2 PF16884.5 KFO97817.1 - 7.4e-27 93.4 0.0 1.4e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KFO97817.1 - 6.3e-15 56.4 0.0 3.2e-14 54.1 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFO97817.1 - 2.1e-14 53.6 0.0 3.4e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Orthopox_F14 PF06076.12 KFO97817.1 - 0.0051 17.0 0.1 0.01 16.1 0.1 1.4 1 0 0 1 1 1 1 Orthopoxvirus F14 protein zf-UBR PF02207.20 KFO97818.1 - 1.9e-21 76.0 11.5 1.9e-21 76.0 11.5 2.7 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KFO97818.1 - 7.7e-20 70.5 0.1 1.8e-19 69.3 0.1 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Ribosomal_L4 PF00573.22 KFO97819.1 - 1.4e-29 103.1 0.0 2.6e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KFO97819.1 - 1.5e-29 101.9 7.0 3.7e-29 100.6 7.0 1.7 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain Ribosomal_L25p PF01386.19 KFO97819.1 - 1.6 9.3 5.7 5.1 7.7 0.1 2.9 2 1 1 3 3 3 0 Ribosomal L25p family SNAPc19 PF15497.6 KFO97820.1 - 2.8e-10 40.5 17.1 3.5e-05 24.2 9.1 2.0 1 1 1 2 2 2 2 snRNA-activating protein complex subunit 19, SNAPc subunit 19 DUF4564 PF15169.6 KFO97820.1 - 0.059 13.1 0.3 0.066 12.9 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4564) Pkinase PF00069.25 KFO97821.1 - 1.1e-57 195.4 0.0 1.4e-57 195.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO97821.1 - 1e-29 103.6 0.0 5.5e-28 98.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFO97821.1 - 3.1e-06 26.2 0.0 4.6e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFO97821.1 - 0.0013 17.8 0.0 0.0016 17.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFO97821.1 - 0.0033 16.8 0.0 0.0067 15.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KFO97821.1 - 0.013 14.6 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 KFO97821.1 - 0.015 14.3 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PIP49_C PF12260.8 KFO97821.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 NAD_binding_6 PF08030.12 KFO97821.1 - 0.17 12.0 0.2 0.5 10.5 0.1 1.8 1 1 1 2 2 2 0 Ferric reductase NAD binding domain Swi3 PF07962.12 KFO97822.1 - 1.4e-34 117.9 0.4 2.1e-34 117.3 0.4 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 RNB PF00773.19 KFO97823.1 - 2.9e-86 289.8 0.1 5.7e-86 288.8 0.1 1.5 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KFO97823.1 - 4e-21 74.8 0.0 1.1e-20 73.4 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 KFO97823.1 - 1.1e-07 31.9 0.0 0.00028 21.0 0.0 3.2 2 1 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 KFO97823.1 - 8e-07 28.9 0.0 1.7e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 KFO97823.1 - 1.1e-06 28.5 0.0 3.7e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 S1 domain OB_RNB PF08206.11 KFO97823.1 - 0.069 12.8 0.0 0.24 11.1 0.0 1.9 1 0 0 1 1 1 0 Ribonuclease B OB domain EMI PF07546.13 KFO97824.1 - 1.2e-17 64.3 8.8 1.2e-17 64.3 8.8 1.8 2 0 0 2 2 2 1 EMI domain EGF_2 PF07974.13 KFO97824.1 - 0.016 15.6 11.2 0.016 15.6 11.2 1.9 1 1 1 2 2 2 0 EGF-like domain hEGF PF12661.7 KFO97824.1 - 0.018 15.6 5.8 0.018 15.6 5.8 3.3 4 0 0 4 4 4 0 Human growth factor-like EGF Laminin_EGF PF00053.24 KFO97825.1 - 2.4e-50 168.5 303.6 0.00038 20.5 15.8 16.8 7 4 9 16 16 16 15 Laminin EGF domain hEGF PF12661.7 KFO97825.1 - 4.3e-14 52.5 259.0 0.00082 19.9 10.1 21.6 21 1 0 21 21 19 12 Human growth factor-like EGF EGF_2 PF07974.13 KFO97825.1 - 4.3e-09 36.6 377.1 0.0045 17.3 11.0 26.0 21 7 3 24 24 24 12 EGF-like domain EGF PF00008.27 KFO97825.1 - 0.0025 18.1 32.7 0.003 17.8 11.8 22.3 23 1 0 23 23 22 12 EGF-like domain Syndecan PF01034.20 KFO97825.1 - 0.0099 15.8 0.2 0.018 14.9 0.2 1.3 1 0 0 1 1 1 1 Syndecan domain MLANA PF14991.6 KFO97825.1 - 0.098 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A Stevor PF17410.2 KFO97825.1 - 0.12 11.9 0.2 0.21 11.1 0.2 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame EphA2_TM PF14575.6 KFO97825.1 - 0.13 13.1 0.0 0.27 12.1 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SIT PF15330.6 KFO97825.1 - 0.14 12.6 1.4 0.41 11.1 1.4 1.8 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Insulin_TMD PF17870.1 KFO97825.1 - 0.15 12.2 1.2 0.27 11.3 1.2 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment RIFIN PF02009.16 KFO97825.1 - 0.16 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Rifin DUF5385 PF17359.2 KFO97825.1 - 0.29 10.7 0.3 0.4 10.2 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF2207 PF09972.9 KFO97825.1 - 0.34 9.6 0.0 0.46 9.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3951 PF13131.6 KFO97825.1 - 0.38 11.0 3.2 0.57 10.4 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3951) SKG6 PF08693.10 KFO97825.1 - 0.57 9.6 4.4 1.1 8.8 4.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ras PF00071.22 KFO97826.1 - 1.3e-62 210.2 0.1 1.5e-62 210.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO97826.1 - 1.3e-34 119.0 0.1 2.4e-34 118.1 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO97826.1 - 2.5e-11 43.4 0.1 2.9e-11 43.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFO97826.1 - 3.5e-07 30.3 0.0 5.8e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KFO97826.1 - 3.6e-05 24.1 0.1 0.00041 20.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KFO97826.1 - 5e-05 23.3 0.1 0.023 14.6 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFO97826.1 - 0.00015 21.4 0.1 0.00034 20.2 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFO97826.1 - 0.0073 16.7 0.1 0.013 15.9 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 KFO97826.1 - 0.03 13.7 0.0 0.045 13.1 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KFO97826.1 - 0.03 13.9 0.1 0.11 12.1 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.27 KFO97826.1 - 0.034 14.7 0.1 0.046 14.2 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 KFO97826.1 - 0.044 13.8 0.1 0.11 12.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 KFO97826.1 - 0.075 12.5 0.0 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KFO97826.1 - 0.078 12.4 0.3 0.23 10.8 0.0 2.2 2 1 0 2 2 2 0 Bacterial TniB protein FAD-SLDH PF12318.8 KFO97826.1 - 0.084 12.9 0.2 0.2 11.7 0.1 1.6 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase PduV-EutP PF10662.9 KFO97826.1 - 0.09 12.5 0.0 0.24 11.1 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 KFO97826.1 - 0.16 11.8 0.8 0.3 10.9 0.5 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DENN PF02141.21 KFO97827.1 - 4e-59 199.7 2.5 1.1e-58 198.2 2.5 1.8 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KFO97827.1 - 7e-17 61.9 0.1 2.9e-16 59.9 0.1 2.2 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KFO97827.1 - 4.6e-14 52.1 5.3 4.6e-14 52.1 5.3 2.1 2 0 0 2 2 2 1 dDENN domain PPR_2 PF13041.6 KFO97827.1 - 6.6e-07 29.4 0.0 2e-05 24.7 0.0 2.6 1 1 1 2 2 2 2 PPR repeat family PPR_3 PF13812.6 KFO97827.1 - 9.2e-05 22.4 0.4 0.00054 20.0 0.1 2.4 2 1 1 3 3 3 2 Pentatricopeptide repeat domain PPR_long PF17177.4 KFO97827.1 - 0.00033 20.1 0.0 0.0028 17.1 0.0 2.4 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KFO97827.1 - 0.0055 16.9 0.0 0.048 13.9 0.0 2.6 2 0 0 2 2 2 1 PPR repeat Papo_T_antigen PF02380.15 KFO97827.1 - 0.45 10.7 5.6 0.16 12.1 1.0 2.5 2 0 0 2 2 2 0 T-antigen specific domain Na_Ca_ex PF01699.24 KFO97828.1 - 2.6e-59 199.5 46.9 1e-31 110.0 23.5 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Cwf_Cwc_15 PF04889.12 KFO97828.1 - 0.047 13.4 9.6 0.069 12.9 9.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 KFO97828.1 - 1.9 8.0 8.3 2.9 7.4 8.3 1.2 1 0 0 1 1 1 0 PPP4R2 DUF4234 PF14018.6 KFO97828.1 - 1.9 8.6 7.2 8.1 6.7 0.3 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) DNA_pol_phi PF04931.13 KFO97828.1 - 6.7 4.7 8.0 10 4.1 8.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi VWA_2 PF13519.6 KFO97829.1 - 1.1e-17 64.7 0.0 4.7e-16 59.4 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KFO97829.1 - 0.012 15.9 0.0 0.037 14.3 0.0 1.8 2 0 0 2 2 2 0 von Willebrand factor type A domain PTPLA PF04387.14 KFO97830.1 - 1.3e-46 158.3 6.0 2.2e-46 157.6 6.0 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA ELO PF01151.18 KFO97830.1 - 0.029 13.9 8.6 0.05 13.1 8.6 1.4 1 1 0 1 1 1 0 GNS1/SUR4 family DPPIV_N PF00930.21 KFO97831.1 - 3.9e-100 335.0 0.0 5.3e-100 334.6 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KFO97831.1 - 1.5e-60 204.3 0.0 2.8e-60 203.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KFO97831.1 - 5.2e-08 32.8 0.0 9.6e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KFO97831.1 - 0.0007 20.3 0.0 0.0015 19.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFO97831.1 - 0.032 13.9 1.1 0.083 12.5 1.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KFO97831.1 - 0.05 13.4 0.0 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.20 KFO97831.1 - 0.095 12.3 0.1 0.3 10.7 0.1 1.8 1 1 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 KFO97831.1 - 0.19 11.6 0.0 0.43 10.4 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold I-set PF07679.16 KFO97832.1 - 1.5e-53 178.8 0.1 1.5e-21 76.3 0.0 4.9 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO97832.1 - 7e-47 157.9 0.0 3.3e-15 56.4 0.1 4.7 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 KFO97832.1 - 6e-29 100.1 0.0 9.6e-09 35.3 0.0 4.7 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFO97832.1 - 1.8e-28 98.7 0.0 1.1e-07 32.0 0.1 4.5 4 0 0 4 4 4 4 Immunoglobulin domain fn3 PF00041.21 KFO97832.1 - 1.8e-23 82.6 3.3 1.2e-13 51.2 0.4 2.6 2 0 0 2 2 2 2 Fibronectin type III domain C2-set_2 PF08205.12 KFO97832.1 - 1.5e-14 53.8 0.3 1.8e-06 28.0 0.1 4.7 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFO97832.1 - 9.5e-13 48.3 2.1 0.01 16.0 0.1 6.3 4 2 1 5 5 5 2 Immunoglobulin V-set domain C1-set PF07654.15 KFO97832.1 - 2.2e-07 31.1 0.2 0.0059 17.0 0.0 3.5 4 0 0 4 4 3 2 Immunoglobulin C1-set domain Ig_5 PF16681.5 KFO97832.1 - 9e-05 22.8 0.1 0.64 10.5 0.0 4.8 5 1 0 5 5 5 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Pur_ac_phosph_N PF16656.5 KFO97832.1 - 0.0012 19.4 1.6 0.0012 19.4 1.6 1.9 2 0 0 2 2 1 1 Purple acid Phosphatase, N-terminal domain Ig_C17orf99 PF17736.1 KFO97832.1 - 0.0014 18.6 0.4 0.014 15.5 0.0 2.9 3 0 0 3 3 3 1 C17orf99 Ig domain BiPBP_C PF06832.12 KFO97832.1 - 0.023 14.7 0.0 3.9 7.6 0.0 2.8 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family Interfer-bind PF09294.10 KFO97832.1 - 0.1 12.9 1.6 0.12 12.7 0.3 1.8 2 0 0 2 2 1 0 Interferon-alpha/beta receptor, fibronectin type III Ig_6 PF18452.1 KFO97832.1 - 0.17 11.5 0.1 1.4 8.5 0.0 2.4 3 0 0 3 3 3 0 Immunoglobulin domain PARP PF00644.20 KFO97833.1 - 1.6e-32 112.7 0.0 2e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ARTD15_N PF18084.1 KFO97833.1 - 1.1e-22 80.0 0.0 2.1e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 ARTD15 N-terminal domain SdpI PF13630.6 KFO97833.1 - 0.031 14.4 0.1 0.067 13.3 0.1 1.5 1 0 0 1 1 1 0 SdpI/YhfL protein family Ig_3 PF13927.6 KFO97834.1 - 2e-12 47.5 0.0 7.2e-12 45.7 0.0 2.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFO97834.1 - 3.4e-10 40.1 0.0 7.8e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain CarbopepD_reg_2 PF13715.6 KFO97834.1 - 1.3e-08 34.8 0.1 0.00034 20.6 0.0 2.6 2 0 0 2 2 2 2 CarboxypepD_reg-like domain CarboxypepD_reg PF13620.6 KFO97834.1 - 3.3e-08 33.7 0.1 7.5e-07 29.3 0.0 2.8 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain I-set PF07679.16 KFO97834.1 - 1.1e-07 31.8 0.0 3.3e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFO97834.1 - 2.2e-07 30.9 0.0 9.3e-07 28.9 0.0 2.1 1 0 0 1 1 1 1 Immunoglobulin domain TSP_1 PF00090.19 KFO97834.1 - 5e-06 26.6 10.7 5e-06 26.6 10.7 2.6 3 0 0 3 3 3 1 Thrombospondin type 1 domain V-set PF07686.17 KFO97834.1 - 0.08 13.1 0.0 5.4 7.2 0.0 2.9 1 1 1 2 2 2 0 Immunoglobulin V-set domain Formyl_trans_N PF00551.19 KFO97835.1 - 8.7e-24 84.2 0.0 1.5e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 KFO97835.1 - 2.9e-12 46.7 0.0 9.1e-12 45.1 0.0 1.9 2 0 0 2 2 2 1 Formyl transferase, C-terminal domain OSTbeta PF15048.6 KFO97836.1 - 9e-34 116.2 0.1 1.1e-33 115.9 0.1 1.1 1 0 0 1 1 1 1 Organic solute transporter subunit beta protein Saf_2TM PF18303.1 KFO97836.1 - 0.021 14.4 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DUF2474 PF10617.9 KFO97836.1 - 1.3 8.9 4.0 2.2 8.2 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) Ras PF00071.22 KFO97837.1 - 5.3e-33 113.9 0.0 6.8e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO97837.1 - 4.7e-08 33.3 0.0 7.2e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO97837.1 - 0.00036 20.0 0.0 0.00055 19.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF815 PF05673.13 KFO97837.1 - 0.071 12.3 0.0 2.1 7.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Kelch_1 PF01344.25 KFO97838.1 - 6.1e-24 83.3 15.2 6e-11 41.8 0.0 6.8 8 0 0 8 8 8 4 Kelch motif Kelch_6 PF13964.6 KFO97838.1 - 1.8e-19 69.3 4.6 1e-07 32.0 0.0 5.4 4 2 1 5 5 5 4 Kelch motif Kelch_2 PF07646.15 KFO97838.1 - 2.2e-14 52.8 1.6 0.00023 21.0 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 KFO97838.1 - 7.6e-13 48.2 4.0 1.4e-06 28.2 0.0 5.0 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 KFO97838.1 - 8.2e-09 35.5 2.4 0.00019 21.7 0.0 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KFO97838.1 - 0.00047 20.1 4.5 2 8.5 0.1 3.6 3 0 0 3 3 3 2 Kelch motif DUF1668 PF07893.13 KFO97838.1 - 0.0016 17.9 0.4 0.3 10.4 0.1 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1668) UBA PF00627.31 KFO97839.1 - 5.8e-05 22.9 0.5 0.018 14.9 0.0 2.3 2 0 0 2 2 2 2 UBA/TS-N domain Sigma54_CBD PF04963.13 KFO97839.1 - 0.01 15.7 0.3 0.01 15.7 0.3 1.1 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain WIYLD PF10440.9 KFO97839.1 - 0.012 15.4 0.0 2 8.2 0.0 2.7 1 1 2 3 3 3 0 Ubiquitin-binding WIYLD domain UBA_3 PF09288.10 KFO97839.1 - 0.032 14.0 1.0 0.75 9.6 0.6 2.4 2 1 0 2 2 2 0 Fungal ubiquitin-associated domain Raf1_HTH PF18579.1 KFO97839.1 - 0.049 13.3 0.2 1.9 8.3 0.0 2.1 1 1 1 2 2 2 0 Rubisco accumulation factor 1 helix turn helix domain AbiEi_4 PF13338.6 KFO97840.1 - 0.037 14.2 0.0 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin PDCD7 PF16021.5 KFO97841.1 - 3e-91 305.8 15.1 3.3e-91 305.6 15.1 1.0 1 0 0 1 1 1 1 Programmed cell death protein 7 DUF3837 PF12939.7 KFO97841.1 - 0.2 12.1 0.3 0.2 12.1 0.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3837) DUF1367 PF07105.11 KFO97841.1 - 0.22 11.1 1.4 0.39 10.4 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1367) Transglut_i_TM PF14400.6 KFO97841.1 - 0.6 10.2 4.0 0.14 12.2 0.8 1.6 2 0 0 2 2 2 0 Inactive transglutaminase fused to 7 transmembrane helices AAA_2 PF07724.14 KFO97842.1 - 2e-25 89.9 0.0 7.3e-24 84.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 KFO97842.1 - 4.9e-15 55.3 0.0 9.2e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KFO97842.1 - 0.14 12.6 0.2 0.51 10.8 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) zinc_ribbon_4 PF13717.6 KFO97842.1 - 0.21 11.6 4.9 8.8 6.3 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 KFO97842.1 - 0.5 10.4 4.6 0.97 9.5 4.6 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Abhydrolase_1 PF00561.20 KFO97843.1 - 3.4e-08 33.4 0.0 4.4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFO97843.1 - 1.5e-06 29.0 0.0 2e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFO97843.1 - 0.0016 17.7 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KFO97843.1 - 0.0067 15.2 0.0 0.0096 14.7 0.0 1.2 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.20 KFO97843.1 - 0.0068 16.5 0.1 0.013 15.7 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.7 KFO97843.1 - 0.035 13.9 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family CUB PF00431.20 KFO97844.1 - 3.8e-15 56.2 0.0 5.3e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 CUB domain Sushi PF00084.20 KFO97844.1 - 2.4e-08 34.5 0.1 3.9e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) CUB PF00431.20 KFO97845.1 - 9.9e-285 923.9 0.0 9.4e-28 96.8 0.0 12.3 12 0 0 12 12 12 12 CUB domain Sushi PF00084.20 KFO97845.1 - 2.5e-249 806.2 162.3 7.1e-12 45.7 0.5 27.4 27 0 0 27 27 27 27 Sushi repeat (SCR repeat) CUB_2 PF02408.20 KFO97845.1 - 3.9e-22 78.3 10.4 0.0054 16.5 0.0 10.7 12 0 0 12 12 12 6 CUB-like domain fn3 PF00041.21 KFO97846.1 - 1e-88 291.8 12.6 1.6e-18 66.8 0.1 6.0 5 0 0 5 5 5 5 Fibronectin type III domain I-set PF07679.16 KFO97846.1 - 5.1e-71 234.8 11.2 1.1e-21 76.7 0.0 8.4 9 0 0 9 9 9 7 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO97846.1 - 8e-50 167.4 4.1 1.2e-12 48.2 0.0 8.2 8 0 0 8 8 8 6 Immunoglobulin domain Ig_2 PF13895.6 KFO97846.1 - 6.4e-34 116.1 2.0 1.6e-07 31.6 0.0 7.6 7 0 0 7 7 7 5 Immunoglobulin domain ig PF00047.25 KFO97846.1 - 6.2e-23 80.8 15.3 1.6e-07 31.4 0.1 8.2 8 0 0 8 8 8 5 Immunoglobulin domain V-set PF07686.17 KFO97846.1 - 7.1e-20 71.2 18.5 0.0019 18.4 0.2 11.1 8 4 1 9 9 9 4 Immunoglobulin V-set domain Tissue_fac PF01108.17 KFO97846.1 - 3.6e-13 49.3 4.1 0.001 18.9 0.0 5.8 6 1 0 6 6 6 4 Tissue factor Pur_ac_phosph_N PF16656.5 KFO97846.1 - 5e-10 39.8 19.3 0.019 15.5 0.8 8.8 9 1 0 9 9 9 4 Purple acid Phosphatase, N-terminal domain Receptor_2B4 PF11465.8 KFO97846.1 - 2.9e-08 33.9 1.0 0.1 12.8 0.0 5.8 6 0 0 6 6 6 1 Natural killer cell receptor 2B4 C2-set_2 PF08205.12 KFO97846.1 - 8.5e-08 32.2 0.1 0.16 12.1 0.0 4.5 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain Y_Y_Y PF07495.13 KFO97846.1 - 0.00056 19.8 2.5 5.6 7.0 0.0 6.1 8 0 0 8 8 8 1 Y_Y_Y domain fn3_2 PF16893.5 KFO97846.1 - 0.0028 17.8 0.1 7.2 6.8 0.0 4.0 3 0 0 3 3 3 1 Fibronectin type III domain Izumo-Ig PF16706.5 KFO97846.1 - 0.08 13.0 0.2 17 5.6 0.0 4.1 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain Cadherin-like PF12733.7 KFO97846.1 - 0.55 10.8 2.6 51 4.5 0.1 3.8 4 0 0 4 4 3 0 Cadherin-like beta sandwich domain RhoGEF PF00621.20 KFO97847.1 - 4.6e-41 141.0 0.9 1e-40 139.9 0.9 1.6 1 0 0 1 1 1 1 RhoGEF domain GKAP PF03359.13 KFO97848.1 - 3.3e-164 546.5 1.4 3.3e-164 546.5 1.4 2.6 2 0 0 2 2 2 1 Guanylate-kinase-associated protein (GKAP) protein Creatininase PF02633.14 KFO97849.1 - 0.084 12.3 0.2 0.13 11.8 0.2 1.3 1 0 0 1 1 1 0 Creatinine amidohydrolase RRP14 PF15459.6 KFO97849.1 - 5.1 7.8 11.6 4.2 8.0 4.9 2.8 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 RVT_1 PF00078.27 KFO97850.1 - 0.084 12.4 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) TDRP PF15683.5 KFO97851.1 - 9.9e-72 239.7 10.6 1.1e-71 239.5 10.6 1.0 1 0 0 1 1 1 1 Testis development-related protein Elongin_A PF06881.11 KFO97852.1 - 0.00058 20.3 0.2 0.00058 20.3 0.2 1.9 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box PF00646.33 KFO97852.1 - 0.0034 17.2 0.1 0.017 15.0 0.0 2.3 2 0 0 2 2 2 1 F-box domain RVT_1 PF00078.27 KFO97853.1 - 0.1 12.1 0.0 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) FAM110_C PF14160.6 KFO97854.1 - 1.4e-35 122.7 0.4 1.4e-35 122.7 0.4 2.4 3 0 0 3 3 3 1 Centrosome-associated C terminus FAM110_N PF14161.6 KFO97854.1 - 1.9e-24 85.9 0.1 5.1e-24 84.6 0.1 1.7 1 0 0 1 1 1 1 Centrosome-associated N terminus LMWPc PF01451.21 KFO97855.1 - 7e-47 159.4 0.1 7.8e-47 159.2 0.1 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase TMEM206 PF15122.6 KFO97855.1 - 0.073 12.2 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 TMEM206 protein family FAM150 PF15129.6 KFO97856.1 - 2.5e-59 198.8 0.7 3e-59 198.6 0.7 1.1 1 0 0 1 1 1 1 FAM150 family TMEM18 PF14770.6 KFO97857.1 - 2.1e-39 134.2 8.1 2.4e-39 134.0 8.1 1.0 1 0 0 1 1 1 1 Transmembrane protein 18 Yae1_N PF09811.9 KFO97858.1 - 9.7e-11 41.2 39.2 0.0018 18.0 5.7 4.1 3 1 1 4 4 4 4 Essential protein Yae1, N terminal PDZ PF00595.24 KFO97859.1 - 9.9e-17 61.1 1.2 1.7e-16 60.3 1.2 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFO97859.1 - 7.4e-10 38.5 0.2 1.8e-09 37.3 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 KFO97859.1 - 1.1e-08 35.5 0.0 0.00097 19.6 0.0 2.7 2 1 0 2 2 2 2 PH domain PDZ_2 PF13180.6 KFO97859.1 - 2.4e-05 24.6 0.1 5.4e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PH_17 PF18012.1 KFO97859.1 - 8.1e-05 22.3 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 PH domain Tricorn_PDZ PF14685.6 KFO97859.1 - 0.042 13.8 0.5 0.38 10.8 0.1 2.4 2 0 0 2 2 2 0 Tricorn protease PDZ domain An_peroxidase PF03098.15 KFO97860.1 - 3.9e-186 619.7 0.0 4.9e-186 619.4 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase EGF_CA PF07645.15 KFO97860.1 - 2e-08 34.3 7.0 2e-08 34.3 7.0 2.4 2 0 0 2 2 2 1 Calcium-binding EGF domain Sushi PF00084.20 KFO97860.1 - 6.5e-06 26.7 4.6 2.4e-05 24.8 4.6 2.1 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) EGF_3 PF12947.7 KFO97860.1 - 3.9e-05 23.8 7.4 0.00014 22.0 7.4 2.1 1 0 0 1 1 1 1 EGF domain FXa_inhibition PF14670.6 KFO97860.1 - 0.0001 22.5 7.6 0.0001 22.5 7.6 2.9 3 0 0 3 3 3 1 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFO97860.1 - 0.00073 19.4 4.9 0.16 11.9 0.7 2.8 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 KFO97860.1 - 0.015 15.3 6.1 0.04 14.0 6.1 1.8 1 0 0 1 1 1 0 MSP1 EGF domain 1 hEGF PF12661.7 KFO97860.1 - 3.4 8.5 8.6 0.34 11.6 2.4 2.6 2 0 0 2 2 2 0 Human growth factor-like EGF An_peroxidase PF03098.15 KFO97861.1 - 1.3e-195 651.0 0.0 2e-195 650.4 0.0 1.3 1 0 0 1 1 1 1 Animal haem peroxidase I-set PF07679.16 KFO97861.1 - 3.6e-87 286.6 0.4 1.8e-20 72.8 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO97861.1 - 7e-77 254.1 6.2 1.4e-19 70.5 0.2 4.7 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFO97861.1 - 5e-51 170.9 2.8 3.4e-12 46.5 0.1 4.7 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 KFO97861.1 - 7.7e-43 144.6 1.2 3.4e-13 49.6 0.0 4.6 4 0 0 4 4 4 4 Immunoglobulin domain LRR_8 PF13855.6 KFO97861.1 - 1.3e-38 130.5 22.5 1.5e-17 63.0 3.4 3.7 1 1 2 3 3 3 3 Leucine rich repeat V-set PF07686.17 KFO97861.1 - 5.3e-23 81.3 12.3 0.00071 19.7 0.2 8.2 4 4 1 5 5 5 5 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFO97861.1 - 5e-19 68.2 3.1 0.0011 19.0 0.0 4.7 4 0 0 4 4 4 4 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFO97861.1 - 6.8e-16 58.4 1.2 0.0012 19.2 0.1 5.3 6 0 0 6 6 4 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain LRR_4 PF12799.7 KFO97861.1 - 1.7e-15 56.9 22.8 1.3e-06 28.6 3.3 5.4 4 1 4 8 8 7 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFO97861.1 - 2.3e-11 43.7 2.6 5.3e-10 39.3 0.1 2.6 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFO97861.1 - 3.4e-11 43.0 2.1 2.6e-05 23.8 0.7 2.4 1 1 1 2 2 2 2 Leucine-rich repeat Ig_4 PF16680.5 KFO97861.1 - 1.9e-09 37.6 0.0 0.017 15.3 0.1 4.9 4 0 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFO97861.1 - 2.3e-09 36.6 0.0 0.46 10.1 0.0 4.8 4 0 0 4 4 4 2 Immunoglobulin domain VWC PF00093.18 KFO97861.1 - 5.5e-09 36.2 18.5 5.5e-09 36.2 18.5 2.9 3 0 0 3 3 2 1 von Willebrand factor type C domain Ig_C17orf99 PF17736.1 KFO97861.1 - 1.9e-07 31.0 0.0 0.16 12.0 0.0 4.1 4 0 0 4 4 4 2 C17orf99 Ig domain Izumo-Ig PF16706.5 KFO97861.1 - 3.2e-05 23.9 0.3 9.8 6.3 0.0 4.5 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain PSP94 PF05825.11 KFO97861.1 - 0.00051 20.5 7.9 0.0015 19.0 7.9 1.7 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) LRR_1 PF00560.33 KFO97861.1 - 0.0016 18.7 9.1 18 6.4 0.2 5.7 4 0 0 4 4 4 0 Leucine Rich Repeat LRRCT PF01463.24 KFO97861.1 - 0.0031 17.9 0.1 0.034 14.7 0.0 2.8 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain Amnionless PF14828.6 KFO97861.1 - 0.0064 15.4 9.4 0.011 14.6 9.4 1.2 1 0 0 1 1 1 1 Amnionless TILa PF12714.7 KFO97861.1 - 0.0087 16.0 11.1 0.0087 16.0 11.1 2.2 2 0 0 2 2 1 1 TILa domain CFC PF09443.10 KFO97861.1 - 0.11 12.4 4.2 0.37 10.7 4.2 2.0 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) DUF4618 PF15397.6 KFO97861.1 - 0.16 11.4 0.9 0.33 10.3 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) fn1 PF00039.18 KFO97861.1 - 1.6 9.0 6.3 6.9 6.9 6.3 2.2 1 0 0 1 1 1 0 Fibronectin type I domain WD40 PF00400.32 KFO97862.1 - 4.5e-16 58.9 8.5 1.5e-05 25.7 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat TPR_2 PF07719.17 KFO97863.1 - 4e-13 48.4 0.0 0.013 15.6 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFO97863.1 - 3.7e-11 42.4 0.0 0.0025 17.6 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFO97863.1 - 8.4e-10 38.8 0.3 0.00019 21.6 0.0 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFO97863.1 - 8.2e-08 32.7 0.0 0.00062 20.2 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFO97863.1 - 2.1e-07 31.4 0.0 0.042 14.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFO97863.1 - 2.2e-05 24.8 0.2 0.0041 17.7 0.0 3.8 5 0 0 5 5 5 1 Tetratricopeptide repeat Coatomer_E PF04733.14 KFO97863.1 - 0.00014 21.3 0.2 0.00038 20.0 0.1 1.7 2 0 0 2 2 2 1 Coatomer epsilon subunit TPR_8 PF13181.6 KFO97863.1 - 0.00096 19.2 0.1 4.8 7.7 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFO97863.1 - 0.0036 17.6 0.9 2 9.0 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFO97863.1 - 0.01 16.6 0.0 60 4.8 0.0 4.1 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KFO97863.1 - 0.017 14.5 0.2 0.032 13.6 0.2 1.5 1 0 0 1 1 1 0 MalT-like TPR region HrpB1_HrpK PF09613.10 KFO97863.1 - 0.041 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_7 PF13176.6 KFO97863.1 - 0.067 13.3 0.0 12 6.2 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO97863.1 - 0.069 13.4 1.1 1.4 9.2 0.1 2.8 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 ARD PF03079.14 KFO97864.1 - 4.5e-58 195.9 0.1 5.2e-58 195.7 0.1 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KFO97864.1 - 2.3e-08 33.7 0.0 3.6e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KFO97864.1 - 1.3e-05 25.1 0.0 2.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_8 PF13621.6 KFO97864.1 - 0.031 14.0 0.0 0.3 10.8 0.0 2.0 1 1 0 1 1 1 0 Cupin-like domain Cupin_1 PF00190.22 KFO97864.1 - 0.035 13.7 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.12 KFO97864.1 - 0.074 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) RNase_H PF00075.24 KFO97865.1 - 4.6e-46 156.6 0.0 7.2e-46 155.9 0.0 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 KFO97865.1 - 6.2e-19 68.0 3.4 1.3e-18 67.0 3.4 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.6 KFO97865.1 - 0.00063 19.6 0.0 0.0018 18.1 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase-like MafB19-deam PF14437.6 KFO97865.1 - 0.082 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 MafB19-like deaminase Ribosomal_S7e PF01251.18 KFO97866.1 - 4.5e-94 313.4 4.1 5e-94 313.2 4.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Lectin_C PF00059.21 KFO97867.1 - 1.5e-17 64.3 0.0 2.3e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain Collagen PF01391.18 KFO97867.1 - 1.3e-14 53.6 53.5 3.1e-09 36.4 24.8 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) WD40 PF00400.32 KFO97868.1 - 5.8e-18 64.9 9.7 3e-08 34.2 0.2 3.6 3 1 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO97868.1 - 3.2e-10 40.2 0.2 0.0017 18.6 0.0 3.2 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFO97868.1 - 4.3e-09 35.6 1.8 0.036 12.7 0.0 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KFO97868.1 - 0.00011 21.3 1.7 0.0078 15.2 0.2 2.8 1 1 3 4 4 4 2 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 KFO97868.1 - 0.00061 18.8 1.3 0.12 11.3 1.2 2.9 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KFO97868.1 - 0.002 17.7 0.4 0.0068 16.0 0.1 1.9 1 1 0 1 1 1 1 PQQ-like domain Hira PF07569.11 KFO97868.1 - 0.006 16.3 0.6 1.6 8.4 0.0 2.9 1 1 2 3 3 3 1 TUP1-like enhancer of split CDtoxinA PF03498.14 KFO97868.1 - 0.022 14.3 0.1 0.033 13.8 0.1 1.3 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain PQQ PF01011.21 KFO97868.1 - 0.078 12.9 0.1 20 5.3 0.0 3.5 4 0 0 4 4 4 0 PQQ enzyme repeat BBS2_Mid PF14783.6 KFO97868.1 - 0.11 12.6 0.0 1.3 9.1 0.0 2.2 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Ank_2 PF12796.7 KFO97869.1 - 1.1e-21 77.2 0.2 3e-17 63.0 0.3 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFO97869.1 - 2.7e-21 75.3 4.6 1.3e-10 41.3 0.3 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 KFO97869.1 - 2.8e-21 76.0 0.0 1.3e-18 67.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Ank PF00023.30 KFO97869.1 - 4.4e-21 74.3 0.7 2.6e-05 24.5 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KFO97869.1 - 4e-20 69.8 0.3 5.2e-06 26.4 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KFO97869.1 - 2e-18 66.5 1.7 3e-10 40.4 0.1 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Pkinase PF00069.25 KFO97869.1 - 1.2e-11 44.5 0.0 4.3e-09 36.1 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pro-kuma_activ PF09286.11 KFO97870.1 - 1.5e-15 57.7 0.0 2.3e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain LCM PF04072.14 KFO97871.1 - 3.7e-28 98.7 0.0 5e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 KFO97871.1 - 8.3e-13 48.1 1.6 0.055 13.5 0.0 6.2 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFO97871.1 - 5.6e-12 45.4 0.1 0.3 11.1 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 KFO97871.1 - 2.2e-11 43.6 4.2 0.00093 19.4 0.0 5.3 4 1 1 5 5 5 2 Kelch motif Kelch_2 PF07646.15 KFO97871.1 - 1.2e-07 31.4 4.8 0.19 11.8 0.1 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 KFO97871.1 - 0.0012 18.3 3.7 0.23 11.1 0.1 4.5 6 0 0 6 6 6 1 Kelch motif Glyoxal_oxid_N PF07250.11 KFO97871.1 - 0.14 11.3 0.1 0.59 9.3 0.0 1.8 2 0 0 2 2 2 0 Glyoxal oxidase N-terminus Kelch_3 PF13415.6 KFO97871.1 - 3.8 7.9 11.7 12 6.3 0.0 5.4 6 0 0 6 6 6 0 Galactose oxidase, central domain dUTPase PF00692.19 KFO97872.1 - 4e-19 68.6 0.0 5.1e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 dUTPase CS PF04969.16 KFO97875.1 - 5.5e-18 65.8 0.3 2.1e-17 63.9 0.3 2.0 1 0 0 1 1 1 1 CS domain EnY2 PF10163.9 KFO97876.1 - 1.8e-35 121.2 0.6 2e-35 121.0 0.6 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 DUF2294 PF10057.9 KFO97876.1 - 0.066 13.3 0.3 0.66 10.1 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2294) DUF3395 PF11875.8 KFO97877.1 - 7.2 6.5 10.8 13 5.6 10.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) Syntaphilin PF15290.6 KFO97878.1 - 7.8e-119 396.9 16.2 1.5e-118 396.1 16.2 1.5 1 0 0 1 1 1 1 Golgi-localised syntaxin-1-binding clamp Fez1 PF06818.15 KFO97878.1 - 0.00015 22.3 7.3 0.00024 21.6 7.3 1.4 1 0 0 1 1 1 1 Fez1 CALCOCO1 PF07888.11 KFO97878.1 - 0.0033 16.4 10.9 0.0053 15.7 10.9 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like FPP PF05911.11 KFO97878.1 - 0.0053 15.0 15.3 0.0085 14.4 15.3 1.2 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil FAM76 PF16046.5 KFO97878.1 - 0.014 14.8 16.7 0.034 13.5 2.7 2.3 1 1 1 2 2 2 0 FAM76 protein HR1 PF02185.16 KFO97878.1 - 0.025 14.7 10.2 0.099 12.8 2.2 2.7 2 0 0 2 2 2 0 Hr1 repeat Atg14 PF10186.9 KFO97878.1 - 0.041 13.0 14.4 0.072 12.2 14.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3584 PF12128.8 KFO97878.1 - 0.064 10.8 8.2 0.09 10.3 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.15 KFO97878.1 - 0.073 12.6 6.6 0.11 12.0 6.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sec8_exocyst PF04048.14 KFO97878.1 - 0.091 12.6 10.3 0.28 11.0 0.4 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain ArAE_1_C PF11728.8 KFO97878.1 - 0.15 12.1 8.0 0.27 11.2 8.0 1.4 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain TPR_MLP1_2 PF07926.12 KFO97878.1 - 0.7 10.0 19.2 0.64 10.1 7.6 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein YgaB PF14182.6 KFO97878.1 - 0.91 10.0 12.1 0.36 11.2 4.0 2.7 1 1 1 2 2 2 0 YgaB-like protein PKcGMP_CC PF16808.5 KFO97878.1 - 1.1 9.2 14.1 0.064 13.1 4.7 3.0 2 2 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CC2-LZ PF16516.5 KFO97878.1 - 1.3 9.5 15.5 0.98 9.8 3.7 2.4 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF745 PF05335.13 KFO97878.1 - 1.8 8.2 7.5 3.2 7.5 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) UPF0242 PF06785.11 KFO97878.1 - 1.9 8.5 18.4 0.56 10.3 15.5 1.5 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF16 PF01519.16 KFO97878.1 - 2.8 8.5 15.6 1.5e+02 2.9 15.4 2.7 2 1 0 2 2 1 0 Protein of unknown function DUF16 Sec2p PF06428.11 KFO97878.1 - 2.9 7.9 16.8 0.14 12.1 3.4 2.8 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p DUF4407 PF14362.6 KFO97878.1 - 3.4 6.9 7.7 5.1 6.4 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 KFO97878.1 - 4.2 5.9 12.7 6.3 5.3 12.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF641 PF04859.12 KFO97878.1 - 4.8 7.5 14.5 0.93 9.8 3.3 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) MPS2 PF17060.5 KFO97878.1 - 5.3 6.2 12.3 29 3.8 12.1 2.0 1 1 0 1 1 1 0 Monopolar spindle protein 2 Prefoldin PF02996.17 KFO97878.1 - 5.9 6.8 11.9 12 5.8 1.5 2.5 2 0 0 2 2 2 0 Prefoldin subunit Spc7 PF08317.11 KFO97878.1 - 5.9 5.7 19.0 15 4.3 19.0 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein PspA_IM30 PF04012.12 KFO97878.1 - 7.1 6.1 15.4 56 3.2 15.4 2.1 1 1 0 1 1 1 0 PspA/IM30 family DUF945 PF06097.11 KFO97879.1 - 4.2e-15 55.8 0.0 0.075 12.1 0.0 8.7 3 2 3 7 7 7 6 Bacterial protein of unknown function (DUF945) Bactofilin PF04519.13 KFO97879.1 - 6.4e-07 29.6 0.1 0.95 9.8 0.0 9.1 11 1 0 11 11 11 1 Polymer-forming cytoskeletal DUF2125 PF09898.9 KFO97879.1 - 0.0097 15.6 0.0 33 4.0 0.0 5.0 5 1 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2125) Coa1 PF08695.10 KFO97879.1 - 0.24 11.2 0.1 1.1e+02 2.6 0.0 5.3 9 1 0 9 9 9 0 Cytochrome oxidase complex assembly protein 1 DNA_pol3_alpha PF07733.12 KFO97879.1 - 0.74 9.4 7.3 82 2.7 0.0 5.6 8 0 0 8 8 8 0 Bacterial DNA polymerase III alpha NTPase domain ELFV_dehydrog_N PF02812.18 KFO97879.1 - 3.1 7.7 7.3 88 3.0 0.0 5.7 7 0 0 7 7 7 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Ntox37 PF15535.6 KFO97879.1 - 9.2 6.8 46.1 1.8 9.1 1.0 10.2 6 5 6 12 12 12 0 Bacterial toxin 37 PDZ PF00595.24 KFO97880.1 - 7e-08 32.7 0.4 2.4e-07 31.0 0.4 1.8 1 1 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFO97880.1 - 4.5e-07 29.6 0.1 1.5e-06 27.9 0.1 1.8 1 1 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFO97880.1 - 1e-05 25.7 0.1 1.6e-05 25.2 0.1 1.2 1 0 0 1 1 1 1 PDZ domain Gln_amidase PF15644.6 KFO97880.1 - 0.043 14.8 0.0 0.22 12.6 0.0 1.9 1 1 0 2 2 2 0 Papain fold toxin 1, glutamine deamidase Pkinase_Tyr PF07714.17 KFO97882.1 - 1.8e-97 325.7 0.0 2.9e-97 325.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.19 KFO97882.1 - 1.5e-71 240.2 0.2 2.8e-71 239.3 0.2 1.5 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.25 KFO97882.1 - 5.1e-46 157.2 0.0 8.5e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 KFO97882.1 - 2e-29 101.8 8.5 2e-15 56.9 1.3 3.7 4 0 0 4 4 4 2 Fibronectin type III domain SAM_1 PF00536.30 KFO97882.1 - 3.1e-22 78.8 0.0 5.5e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFO97882.1 - 5.1e-21 74.6 0.0 9.7e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EphA2_TM PF14575.6 KFO97882.1 - 2.7e-20 73.0 0.0 6.5e-20 71.8 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Ephrin_rec_like PF07699.13 KFO97882.1 - 9.6e-06 25.3 10.4 9.6e-06 25.3 10.4 2.7 2 0 0 2 2 2 1 Putative ephrin-receptor like Pur_ac_phosph_N PF16656.5 KFO97882.1 - 0.00028 21.4 3.0 0.00062 20.3 0.7 2.5 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Tissue_fac PF01108.17 KFO97882.1 - 0.0012 18.7 0.2 0.11 12.4 0.0 2.6 2 0 0 2 2 2 1 Tissue factor fn3_2 PF16893.5 KFO97882.1 - 0.0047 17.0 0.8 2.6 8.2 0.0 2.6 2 0 0 2 2 2 2 Fibronectin type III domain DUF2318 PF10080.9 KFO97882.1 - 0.0098 16.0 1.9 0.035 14.2 1.9 1.9 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) Interfer-bind PF09294.10 KFO97882.1 - 0.011 16.0 0.3 0.18 12.2 0.1 2.7 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III DUF4998 PF16389.5 KFO97882.1 - 0.013 15.1 0.1 0.029 13.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function Haspin_kinase PF12330.8 KFO97882.1 - 0.013 14.5 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain SusE PF14292.6 KFO97882.1 - 0.022 15.0 0.1 10 6.4 0.1 2.6 2 0 0 2 2 2 0 SusE outer membrane protein Y_Y_Y PF07495.13 KFO97882.1 - 0.051 13.5 0.4 0.97 9.4 0.6 2.4 2 0 0 2 2 2 0 Y_Y_Y domain Kdo PF06293.14 KFO97882.1 - 0.08 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EGF_MSP1_1 PF12946.7 KFO97882.1 - 2.7 8.1 6.6 0.38 10.8 1.7 2.1 2 0 0 2 2 2 0 MSP1 EGF domain 1 Yae1_N PF09811.9 KFO97883.1 - 7.3e-17 60.8 51.7 3.4e-05 23.4 8.8 5.4 2 2 2 4 4 4 4 Essential protein Yae1, N terminal GIDA PF01134.22 KFO97884.1 - 8e-96 321.5 0.0 1.1e-95 321.0 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KFO97884.1 - 1.5e-64 218.0 0.0 2.1e-64 217.6 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain Hexapep_2 PF14602.6 KFO97884.1 - 0.012 15.4 0.2 0.022 14.5 0.2 1.5 1 0 0 1 1 1 0 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 KFO97884.1 - 0.24 11.2 0.4 0.55 10.1 0.4 1.6 1 0 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) Mab-21 PF03281.14 KFO97885.1 - 1e-76 258.1 2.6 1.1e-76 257.9 2.6 1.0 1 0 0 1 1 1 1 Mab-21 protein DEAD PF00270.29 KFO97886.1 - 4.3e-40 137.3 0.0 3.5e-39 134.4 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFO97886.1 - 2.1e-28 98.9 0.0 3.1e-27 95.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain KH_1 PF00013.29 KFO97886.1 - 6.1e-07 29.2 0.1 1.6e-06 27.9 0.1 1.7 1 0 0 1 1 1 1 KH domain MOEP19 PF16005.5 KFO97886.1 - 0.0031 17.5 0.0 0.17 11.9 0.0 2.4 2 0 0 2 2 2 1 KH-like RNA-binding domain ResIII PF04851.15 KFO97886.1 - 0.011 15.8 0.0 0.029 14.4 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Ppx-GppA PF02541.16 KFO97886.1 - 0.014 14.9 0.1 0.061 12.7 0.1 1.9 2 0 0 2 2 2 0 Ppx/GppA phosphatase family KCNQ_channel PF03520.14 KFO97887.1 - 7e-94 313.0 2.0 7e-94 313.0 2.0 1.6 2 0 0 2 2 2 1 KCNQ voltage-gated potassium channel Ion_trans PF00520.31 KFO97887.1 - 2.9e-26 92.2 10.7 4.1e-26 91.7 10.7 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFO97887.1 - 3e-14 52.7 5.7 8.1e-14 51.4 5.7 1.8 1 0 0 1 1 1 1 Ion channel IQ PF00612.27 KFO97887.1 - 1.7 8.7 5.1 1.1 9.2 0.1 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif YdaS_antitoxin PF15943.5 KFO97889.1 - 1.8 8.5 10.1 1.3e+02 2.6 0.1 5.2 5 1 1 6 6 6 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF5600 PF18150.1 KFO97891.1 - 1.7e-40 137.9 0.3 2.9e-40 137.2 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 KFO97891.1 - 2.7e-18 65.8 0.0 1.2e-17 63.7 0.0 2.0 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KFO97891.1 - 0.0015 18.0 0.1 0.0055 16.2 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KFO97891.1 - 0.0029 17.4 0.4 1.4 8.8 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair Gtr1_RagA PF04670.12 KFO97891.1 - 0.023 14.1 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region EF-hand_5 PF13202.6 KFO97891.1 - 0.035 13.6 0.1 0.11 12.1 0.1 1.8 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KFO97891.1 - 0.081 12.9 0.0 0.32 11.0 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 KFO97891.1 - 0.092 13.2 0.0 0.79 10.2 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair Connexin PF00029.19 KFO97892.1 - 4.4e-86 288.5 0.4 4.9e-86 288.3 0.4 1.0 1 0 0 1 1 1 1 Connexin 7tm_4 PF13853.6 KFO97893.1 - 1.2e-15 58.0 1.8 1.3e-15 57.9 1.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO97893.1 - 0.1 11.9 2.6 0.12 11.6 2.6 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) IMD PF08397.11 KFO97894.1 - 5.8e-62 208.9 3.9 7.3e-62 208.6 3.9 1.1 1 0 0 1 1 1 1 IRSp53/MIM homology domain SH3_9 PF14604.6 KFO97894.1 - 7.9e-11 41.7 0.0 1.4e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFO97894.1 - 2.3e-07 30.4 0.0 4e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFO97894.1 - 2.4e-06 27.0 0.0 4.5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain BAR_3 PF16746.5 KFO97894.1 - 0.00022 21.0 9.3 0.00087 19.1 9.3 1.8 1 1 0 1 1 1 1 BAR domain of APPL family Rhabdo_M1 PF03342.13 KFO97894.1 - 0.056 12.8 0.8 0.12 11.8 0.8 1.5 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) LMBR1 PF04791.16 KFO97894.1 - 1.4 7.7 2.6 2.1 7.1 2.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein OrfB_IS605 PF01385.19 KFO97894.1 - 2 8.7 6.0 0.6 10.3 0.1 2.4 1 1 1 2 2 2 0 Probable transposase DUF2367 PF10164.9 KFO97895.1 - 6.6e-37 126.2 6.6 7.7e-37 126.0 6.6 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) DUF4126 PF13548.6 KFO97895.1 - 0.021 14.5 1.4 0.024 14.3 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4126) zf-RING_4 PF14570.6 KFO97895.1 - 0.042 13.6 1.2 4.9 7.0 0.2 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ribbon_3 PF13248.6 KFO97895.1 - 0.12 11.8 0.2 0.12 11.8 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 KFO97895.1 - 0.13 12.0 3.3 7.6 6.4 0.0 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf_Rg PF17915.1 KFO97895.1 - 0.19 11.1 4.5 1.1 8.7 0.3 2.2 2 0 0 2 2 2 0 Reverse gyrase zinc finger DUF1936 PF09151.10 KFO97895.1 - 0.46 10.4 0.4 0.46 10.4 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) Hyd_WA PF06462.12 KFO97896.1 - 1.9e-68 226.1 61.8 9.2e-12 44.7 2.2 10.6 12 0 0 12 12 12 8 Propeller Pex24p PF06398.11 KFO97896.1 - 2.7e-22 79.3 20.6 3.6e-12 45.9 4.6 2.2 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin PH PF00169.29 KFO97896.1 - 0.0021 18.5 1.5 0.0037 17.7 0.2 2.1 2 0 0 2 2 2 1 PH domain HLH PF00010.26 KFO97897.1 - 3.3e-17 62.2 4.1 6.9e-17 61.1 4.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RepB PF07506.11 KFO97897.1 - 0.022 14.8 1.8 0.03 14.4 1.8 1.3 1 0 0 1 1 1 0 RepB plasmid partitioning protein DUF2205 PF10224.9 KFO97897.1 - 0.038 14.0 0.3 0.066 13.2 0.3 1.4 1 0 0 1 1 1 0 Short coiled-coil protein PhoR PF11808.8 KFO97897.1 - 3.8 8.0 4.5 2.6 8.5 0.7 2.2 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR Pkinase_Tyr PF07714.17 KFO97898.1 - 1.9e-54 184.7 0.0 2.8e-54 184.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO97898.1 - 2e-27 96.2 0.0 3.9e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain ACI44 PF15270.6 KFO97898.1 - 0.22 11.8 7.6 10 6.4 1.6 3.6 3 0 0 3 3 3 0 Metallo-carboxypeptidase inhibitor Orexin_rec2 PF03827.13 KFO97898.1 - 2 8.5 3.7 1.3 9.1 0.4 2.3 2 0 0 2 2 2 0 Orexin receptor type 2 EF-hand_1 PF00036.32 KFO97899.1 - 2.2e-12 45.6 1.7 5.3e-05 22.5 0.4 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFO97899.1 - 7.7e-12 45.5 0.1 1.2e-11 44.9 0.1 1.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFO97899.1 - 1.6e-11 43.1 0.5 2.9e-05 23.6 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KFO97899.1 - 6.4e-11 41.2 2.7 2.8e-05 23.4 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFO97899.1 - 1.3e-06 28.2 0.7 2.3e-05 24.1 0.2 2.3 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFO97899.1 - 0.0028 18.0 0.0 0.0044 17.3 0.0 1.4 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_1 PF00036.32 KFO97900.1 - 8.7e-12 43.7 2.1 5.5e-05 22.4 0.4 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFO97900.1 - 1.1e-11 45.0 0.5 1.4e-11 44.7 0.5 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFO97900.1 - 8.7e-11 40.9 1.3 4.6e-05 23.0 0.1 2.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KFO97900.1 - 1.5e-09 36.9 3.2 0.00026 20.3 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFO97900.1 - 1.1e-05 25.2 1.5 0.00011 22.0 0.4 2.2 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFO97900.1 - 0.0071 16.7 0.0 0.01 16.2 0.0 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.10 KFO97900.1 - 0.0087 16.1 0.2 0.27 11.3 0.1 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand QueF_N PF14819.6 KFO97900.1 - 0.05 13.9 0.0 0.058 13.7 0.0 1.2 1 0 0 1 1 1 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term EF-hand_7 PF13499.6 KFO97901.1 - 1.1e-14 54.7 0.6 1.5e-14 54.2 0.6 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFO97901.1 - 3.2e-14 51.3 2.7 5.8e-07 28.6 0.7 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFO97901.1 - 5.1e-12 44.7 2.3 4.1e-06 26.3 0.5 3.0 2 1 1 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KFO97901.1 - 6.2e-10 38.1 4.1 7.5e-05 22.0 0.1 2.5 2 1 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFO97901.1 - 1.8e-06 27.6 1.0 0.019 14.8 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFO97901.1 - 0.029 14.7 0.1 0.05 13.9 0.1 1.5 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Toprim_2 PF13155.6 KFO97901.1 - 0.12 12.8 0.0 18 5.8 0.0 2.1 1 1 1 2 2 2 0 Toprim-like EF-hand_10 PF14788.6 KFO97901.1 - 0.17 11.8 2.7 0.58 10.1 0.6 2.4 2 1 1 3 3 3 0 EF hand DUF1712 PF08217.11 KFO97902.1 - 1e-95 321.5 8.7 4.6e-86 289.6 1.3 2.1 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1712) MORN PF02493.20 KFO97903.1 - 6e-18 63.6 31.8 6.7e-08 32.0 1.4 5.3 5 1 0 5 5 5 5 MORN repeat MutL_C PF08676.11 KFO97904.1 - 4.2e-30 104.5 0.0 1.1e-29 103.1 0.0 1.8 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KFO97904.1 - 4.9e-24 84.3 0.2 3.6e-23 81.5 0.0 2.2 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KFO97904.1 - 3.5e-12 46.3 0.1 1.2e-11 44.5 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KFO97904.1 - 6.3e-06 26.7 2.0 2.8e-05 24.6 0.1 2.6 2 1 1 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Thioredoxin_16 PF18569.1 KFO97905.1 - 1.6e-37 127.5 0.4 2.8e-37 126.7 0.4 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain GST_C PF00043.25 KFO97905.1 - 8.7e-06 25.9 0.0 2.1e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFO97905.1 - 9.7e-06 25.7 0.0 6.9e-05 23.0 0.0 2.3 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFO97905.1 - 2.2e-05 24.4 0.1 6.7e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KFO97905.1 - 0.00055 19.7 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Potex_coat PF06184.11 KFO97905.1 - 0.11 12.0 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 Potexvirus coat protein Pkinase PF00069.25 KFO97906.1 - 1.7e-45 155.5 0.7 7.8e-29 100.8 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFO97906.1 - 7.1e-25 87.8 1.2 5.9e-18 65.1 0.2 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase DUF641 PF04859.12 KFO97906.1 - 0.0057 17.0 1.7 0.0057 17.0 1.7 1.9 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) FTA2 PF13095.6 KFO97906.1 - 0.015 15.0 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF16 PF01519.16 KFO97906.1 - 0.019 15.4 2.4 0.044 14.3 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 P4Ha_N PF08336.11 KFO97906.1 - 0.028 14.5 1.5 0.065 13.2 1.5 1.6 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region SlyX PF04102.12 KFO97906.1 - 0.18 12.4 5.8 0.075 13.7 2.3 2.1 2 0 0 2 2 2 0 SlyX Csm1_N PF18504.1 KFO97906.1 - 0.24 11.8 3.3 0.68 10.3 3.3 1.7 1 0 0 1 1 1 0 Csm1 N-terminal domain DivIC PF04977.15 KFO97906.1 - 0.26 11.1 4.3 0.23 11.3 2.2 1.9 2 0 0 2 2 2 0 Septum formation initiator UCH PF00443.29 KFO97907.1 - 4e-49 167.4 1.2 4e-49 167.4 1.2 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFO97907.1 - 1.2e-18 67.8 3.0 1.2e-18 67.8 3.0 3.5 3 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase zf_UBZ PF18439.1 KFO97907.1 - 0.058 13.0 2.5 0.26 10.9 0.2 2.8 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Sec7 PF01369.20 KFO97908.1 - 7.6e-68 227.8 0.1 9.6e-68 227.5 0.1 1.1 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 KFO97908.1 - 1.6e-28 99.3 0.1 2.4e-28 98.7 0.1 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFO97908.1 - 1.3e-05 25.5 0.3 4.9e-05 23.7 0.3 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KFO97908.1 - 0.021 14.9 0.0 0.061 13.4 0.0 1.8 1 1 0 1 1 1 0 PH domain PH_8 PF15409.6 KFO97908.1 - 0.026 14.8 0.0 0.098 12.9 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain PH_6 PF15406.6 KFO97908.1 - 0.15 12.4 0.0 29 5.0 0.0 2.4 1 1 1 2 2 2 0 Pleckstrin homology domain DnaJ_C PF01556.18 KFO97909.1 - 1e-36 126.2 0.0 1.2e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain Mito_carr PF00153.27 KFO97910.1 - 8.3e-58 192.3 3.9 1.5e-23 82.5 0.0 4.0 3 1 1 4 4 4 4 Mitochondrial carrier protein Colicin_V PF02674.16 KFO97910.1 - 0.14 12.2 1.3 0.41 10.6 0.2 2.2 2 1 0 2 2 2 0 Colicin V production protein Glyco_transf_7N PF13733.6 KFO97911.1 - 8.3e-56 187.3 0.0 1.3e-55 186.7 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 KFO97911.1 - 4.6e-29 99.9 0.4 8e-29 99.1 0.4 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Na_H_Exchanger PF00999.21 KFO97912.1 - 3.5e-62 210.4 40.1 4.3e-62 210.1 40.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family zf-B_box PF00643.24 KFO97913.1 - 2.3 8.5 17.8 1.3 9.2 4.4 3.1 2 1 0 2 2 2 0 B-box zinc finger zf-Di19 PF05605.12 KFO97914.1 - 2e-18 66.4 2.4 2e-18 66.4 2.4 3.1 2 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf_C2HC_14 PF18574.1 KFO97914.1 - 1.6e-15 56.6 5.9 1.6e-15 56.6 5.9 2.3 2 0 0 2 2 2 1 C2HC Zing finger domain zf-RRN7 PF11781.8 KFO97914.1 - 0.0093 15.6 7.9 0.85 9.4 0.2 3.5 3 0 0 3 3 3 2 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-C2H2_4 PF13894.6 KFO97914.1 - 0.022 15.6 0.9 0.022 15.6 0.9 4.5 4 1 0 4 4 4 0 C2H2-type zinc finger DND1_DSRM PF14709.7 KFO97914.1 - 0.024 14.9 0.0 0.07 13.4 0.0 1.8 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 tRNA-synt_1g PF09334.11 KFO97914.1 - 0.07 11.9 4.6 0.027 13.2 1.6 1.8 1 1 1 2 2 2 0 tRNA synthetases class I (M) DZR PF12773.7 KFO97914.1 - 0.59 10.2 18.6 2.4 8.3 1.8 2.6 2 1 0 2 2 2 0 Double zinc ribbon YdjO PF14169.6 KFO97914.1 - 0.59 9.9 9.6 1.4 8.8 0.0 3.9 4 0 0 4 4 4 0 Cold-inducible protein YdjO zf_UBZ PF18439.1 KFO97914.1 - 1.6 8.4 9.1 2.8 7.6 0.0 3.9 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C4pol PF14260.6 KFO97914.1 - 8.8 6.9 17.5 2.5 8.6 9.9 2.5 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta zf-C2H2 PF00096.26 KFO97915.1 - 1.4e-24 85.1 31.6 6e-06 26.4 0.7 5.2 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO97915.1 - 1e-18 66.4 32.1 0.00012 22.6 1.4 5.2 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO97915.1 - 3.4e-14 52.7 18.7 0.00045 20.4 0.2 5.4 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KFO97915.1 - 1.2e-13 50.8 38.1 3.1e-07 30.5 0.5 5.9 5 2 0 5 5 5 3 Zinc-finger double domain zf-met PF12874.7 KFO97915.1 - 4.4e-09 36.4 17.9 0.0032 17.8 0.8 4.4 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFO97915.1 - 4.2e-08 33.0 33.4 0.0016 18.4 1.2 5.5 5 1 0 5 5 5 4 C2H2-type zinc finger zf-C2HE PF16278.5 KFO97915.1 - 8.3e-07 29.4 23.8 0.023 15.1 0.7 4.9 1 1 4 5 5 5 3 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 KFO97915.1 - 0.0043 17.4 22.5 0.99 9.8 1.0 4.9 1 1 4 5 5 5 2 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 KFO97915.1 - 0.0072 17.0 1.0 0.0072 17.0 1.0 3.0 2 1 0 2 2 1 1 zinc-ribbon family Zn-ribbon_8 PF09723.10 KFO97915.1 - 0.013 15.6 21.3 0.23 11.6 0.7 4.3 1 1 4 5 5 5 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 KFO97915.1 - 0.018 15.0 13.6 0.65 10.0 0.6 4.5 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-BED PF02892.15 KFO97915.1 - 0.018 15.0 27.8 0.11 12.5 0.8 5.1 2 2 3 5 5 5 0 BED zinc finger zf-AN1 PF01428.16 KFO97915.1 - 0.022 14.9 21.0 3.4 7.9 1.7 5.2 5 0 0 5 5 5 0 AN1-like Zinc finger PyrI_C PF02748.15 KFO97915.1 - 0.085 12.8 15.3 0.87 9.5 2.1 4.7 5 0 0 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_11 PF16622.5 KFO97915.1 - 0.87 9.4 27.8 5.3 6.9 0.6 5.2 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-CHY PF05495.12 KFO97915.1 - 1.3 9.6 26.8 1.2 9.7 6.1 2.6 1 1 1 2 2 2 0 CHY zinc finger Spt46 PF17734.1 KFO97915.1 - 2.6 7.8 16.7 0.85 9.4 4.2 3.6 1 1 2 4 4 4 0 Spermatogenesis-associated protein 46 DUF2180 PF09947.9 KFO97915.1 - 2.6 8.1 8.8 0.81 9.7 2.6 2.7 3 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) zf_ZIC PF18366.1 KFO97915.1 - 4.4 7.5 14.9 5 7.3 1.6 4.7 1 1 3 5 5 5 0 Zic proteins zinc finger domain Zn_Tnp_IS1595 PF12760.7 KFO97915.1 - 4.9 7.2 28.5 2.5 8.1 0.6 3.8 3 1 0 3 3 3 0 Transposase zinc-ribbon domain XPA_N PF01286.18 KFO97915.1 - 5.4 7.1 15.5 3.6 7.7 0.1 4.7 5 0 0 5 5 5 0 XPA protein N-terminal Sprouty PF05210.13 KFO97915.1 - 6.6 7.2 18.3 0.42 11.0 2.0 2.7 2 1 0 2 2 2 0 Sprouty protein (Spry) TMEM189_B_dmain PF10520.9 KFO97916.1 - 8.3e-29 100.9 2.1 1.3e-28 100.3 2.1 1.3 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain UQ_con PF00179.26 KFO97916.1 - 6.6e-18 64.7 0.0 1e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFO97916.1 - 0.038 14.3 0.0 0.052 13.8 0.0 1.4 1 0 0 1 1 1 0 RWD domain Cmyb_C PF09316.10 KFO97917.1 - 1.4e-64 216.7 4.6 3.1e-64 215.6 4.6 1.6 1 0 0 1 1 1 1 C-myb, C-terminal Myb_DNA-binding PF00249.31 KFO97917.1 - 3.4e-50 168.0 17.3 3.3e-17 62.4 3.2 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFO97917.1 - 2.8e-45 152.4 13.6 4.9e-19 68.3 2.7 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFO97917.1 - 9.6e-08 31.8 5.3 0.0058 16.5 0.0 3.5 2 1 1 3 3 3 3 Myb DNA-binding like SLIDE PF09111.10 KFO97917.1 - 4.3e-06 26.7 1.4 0.5 10.4 0.0 3.4 1 1 2 3 3 3 3 SLIDE Sigma70_r4_2 PF08281.12 KFO97917.1 - 0.0012 18.4 0.0 0.003 17.2 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 SANT_DAMP1_like PF16282.5 KFO97917.1 - 0.0088 16.2 5.5 1.8 8.8 0.1 3.5 1 1 2 3 3 3 1 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 KFO97917.1 - 0.035 14.2 6.1 17 5.6 4.5 3.6 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Atg29_N PF18388.1 KFO97917.1 - 0.12 12.2 0.6 0.71 9.7 0.0 2.4 2 0 0 2 2 2 0 Atg29 N-terminal domain Myb_DNA-bind_2 PF08914.11 KFO97917.1 - 8.4 6.7 6.8 19 5.5 0.2 3.3 1 1 2 3 3 3 0 Rap1 Myb domain ABC_transp_aux PF09822.9 KFO97919.1 - 2.2e-07 30.6 0.0 3.8e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DDOST_48kD PF03345.14 KFO97919.1 - 0.0083 15.0 0.0 0.75 8.6 0.0 2.1 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Pkinase PF00069.25 KFO97920.1 - 1.4e-68 231.2 0.0 1.6e-68 230.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO97920.1 - 2e-35 122.3 0.0 2.5e-35 122.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KFO97920.1 - 2.2e-06 28.3 0.1 5.6e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFO97920.1 - 8.9e-06 25.2 0.1 2.8e-05 23.6 0.1 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFO97920.1 - 0.0015 18.0 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KFO97920.1 - 0.0086 15.7 0.0 0.62 9.7 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KFO97920.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Aa_trans PF01490.18 KFO97921.1 - 3e-99 332.5 18.8 3.5e-99 332.3 18.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RhoGAP PF00620.27 KFO97922.1 - 4.9e-43 146.6 0.3 4.9e-43 146.6 0.3 2.0 2 1 0 2 2 2 1 RhoGAP domain UBN_AB PF14075.6 KFO97922.1 - 0.06 13.1 1.6 0.13 12.0 1.6 1.5 1 0 0 1 1 1 0 Ubinuclein conserved middle domain GrpE PF01025.19 KFO97922.1 - 0.096 12.3 1.4 0.21 11.3 1.0 1.8 2 0 0 2 2 2 0 GrpE Actin PF00022.19 KFO97923.1 - 1.4e-42 145.8 0.0 7.8e-26 90.6 0.0 2.3 2 1 0 2 2 2 2 Actin DUF2777 PF10949.8 KFO97923.1 - 0.097 12.3 1.8 0.21 11.3 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) DUF4265 PF14085.6 KFO97923.1 - 0.1 12.5 0.1 24 4.9 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4265) MreB_Mbl PF06723.13 KFO97923.1 - 0.23 10.3 0.0 0.36 9.6 0.0 1.2 1 0 0 1 1 1 0 MreB/Mbl protein DUF1542 PF07564.11 KFO97923.1 - 0.37 10.9 2.2 3.2 7.9 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) FAM83 PF07894.12 KFO97924.1 - 1.4e-76 257.7 0.0 2.7e-76 256.7 0.0 1.5 2 0 0 2 2 2 1 FAM83 A-H PLDc_2 PF13091.6 KFO97924.1 - 2.5e-07 30.6 0.0 5.6e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 PLD-like domain FAM83 PF07894.12 KFO97925.1 - 2.5e-38 132.2 0.7 2.4e-25 89.6 0.8 2.1 1 1 1 2 2 2 2 FAM83 A-H PLDc_2 PF13091.6 KFO97925.1 - 0.028 14.3 0.1 0.065 13.1 0.1 1.7 1 1 0 1 1 1 0 PLD-like domain GHL6 PF14871.6 KFO97925.1 - 0.075 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 HA2 PF04408.23 KFO97926.1 - 2.1e-20 73.0 0.1 5.4e-20 71.7 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFO97926.1 - 1.6e-19 70.1 0.0 3.5e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFO97926.1 - 2.7e-14 53.5 0.1 5.9e-14 52.3 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ABC_tran PF00005.27 KFO97926.1 - 0.00012 22.6 0.2 0.037 14.5 0.1 2.7 1 1 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 KFO97926.1 - 0.00026 21.2 0.1 0.0015 18.8 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFO97926.1 - 0.016 14.9 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KFO97926.1 - 0.041 14.2 0.0 0.18 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFO97926.1 - 0.081 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region 14-3-3 PF00244.20 KFO97927.1 - 1.2e-108 361.7 10.4 1.4e-108 361.6 10.4 1.0 1 0 0 1 1 1 1 14-3-3 protein Peptidase_C98 PF15499.6 KFO97927.1 - 0.02 14.4 0.3 0.035 13.6 0.3 1.5 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase FliM PF02154.15 KFO97927.1 - 0.051 13.5 0.2 0.087 12.7 0.2 1.3 1 0 0 1 1 1 0 Flagellar motor switch protein FliM SF3A2 PF16835.5 KFO97927.1 - 0.12 12.8 0.4 0.34 11.3 0.2 1.8 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) DUF4518 PF15008.6 KFO97927.1 - 0.14 11.4 5.4 3.2 6.8 5.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) Virulence_fact PF13769.6 KFO97927.1 - 1.8 8.8 7.7 0.91 9.8 0.7 2.9 2 1 1 3 3 3 0 Virulence factor YabA PF06156.13 KFO97927.1 - 3.2 8.5 6.6 1.2 9.9 2.6 2.2 3 0 0 3 3 3 0 Initiation control protein YabA TPR_1 PF00515.28 KFO97928.1 - 1.6e-19 68.8 8.2 1.2e-10 40.7 0.5 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFO97928.1 - 2.1e-17 61.8 6.1 1.3e-07 31.2 0.4 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFO97928.1 - 2.4e-11 42.9 10.0 5.2e-06 26.2 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFO97928.1 - 4e-10 40.2 0.1 4.2e-05 24.1 0.0 2.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFO97928.1 - 1e-09 37.9 4.2 7.1e-06 25.6 0.4 2.5 2 0 0 2 2 2 2 TPR repeat TPR_14 PF13428.6 KFO97928.1 - 9.4e-08 32.3 0.8 0.0067 17.2 0.7 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFO97928.1 - 9.9e-08 31.9 5.9 0.00017 21.7 0.1 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFO97928.1 - 1e-07 32.1 5.4 0.00066 19.9 1.7 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFO97928.1 - 1.1e-06 29.1 7.0 1.1e-05 25.9 4.1 2.5 2 1 1 3 3 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFO97928.1 - 4.3e-06 26.7 6.1 0.0044 17.0 0.4 3.1 2 1 1 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 KFO97928.1 - 7.6e-06 26.0 1.2 0.00062 19.9 0.2 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFO97928.1 - 0.00019 21.9 6.6 0.23 12.2 0.4 3.8 2 2 1 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.17 KFO97928.1 - 0.00036 21.0 1.1 0.00062 20.2 1.1 1.4 1 0 0 1 1 1 1 Bacterial transcriptional activator domain TPR_7 PF13176.6 KFO97928.1 - 0.00042 20.1 1.2 0.14 12.2 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO97928.1 - 0.00054 20.1 8.0 0.0014 18.8 7.8 1.8 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 KFO97928.1 - 0.0031 17.5 8.9 1.3 9.1 6.4 3.2 1 1 1 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 KFO97928.1 - 0.027 14.3 2.4 0.48 10.4 0.3 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KFO97928.1 - 0.041 13.3 5.7 2.8 7.5 0.1 3.5 4 0 0 4 4 4 0 SHNi-TPR PaREP1 PF05942.11 KFO97928.1 - 0.18 11.7 3.3 0.4 10.6 3.2 1.8 1 1 0 1 1 1 0 Archaeal PaREP1/PaREP8 family DUF627 PF04781.12 KFO97928.1 - 0.38 10.8 7.1 1.6 8.8 2.4 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF627) Ribosomal_L12 PF00542.19 KFO97928.1 - 0.84 10.0 3.6 7.1 7.1 0.4 2.7 2 1 1 3 3 3 0 Ribosomal protein L7/L12 C-terminal domain Ion_trans PF00520.31 KFO97929.1 - 3e-45 154.4 0.7 3.9e-45 154.0 0.7 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFO97929.1 - 3.6e-30 104.2 0.1 8.2e-30 103.0 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFO97929.1 - 2e-10 40.5 4.6 2e-10 40.5 4.6 2.6 3 0 0 3 3 3 1 Ion channel BTB_3 PF16017.5 KFO97929.1 - 0.044 13.9 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain VWA PF00092.28 KFO97930.1 - 2.1e-100 334.2 0.2 1.3e-52 178.6 0.0 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 KFO97930.1 - 1.8e-36 125.0 0.1 2.4e-17 63.5 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain FXa_inhibition PF14670.6 KFO97930.1 - 2.8e-31 107.5 63.7 1.1e-08 35.2 9.8 4.5 4 0 0 4 4 4 4 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFO97930.1 - 5.2e-21 74.2 32.9 3e-07 30.2 2.7 4.9 4 0 0 4 4 4 4 Complement Clr-like EGF-like EGF_CA PF07645.15 KFO97930.1 - 3.8e-19 68.6 51.2 4.9e-08 33.0 5.5 4.4 4 0 0 4 4 4 4 Calcium-binding EGF domain EGF PF00008.27 KFO97930.1 - 1.8e-10 40.9 53.8 0.0028 17.9 7.8 4.6 4 0 0 4 4 4 4 EGF-like domain Matrilin_ccoil PF10393.9 KFO97930.1 - 4.7e-09 36.0 0.1 1.3e-08 34.5 0.1 1.8 1 0 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin VWA_3 PF13768.6 KFO97930.1 - 2.4e-06 27.6 0.1 0.064 13.2 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain hEGF PF12661.7 KFO97930.1 - 0.00012 22.5 40.7 0.036 14.7 4.6 5.2 4 0 0 4 4 4 3 Human growth factor-like EGF ClpB_D2-small PF10431.9 KFO97930.1 - 0.013 15.5 0.0 4.5 7.4 0.0 2.5 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein EGF_MSP1_1 PF12946.7 KFO97930.1 - 0.015 15.4 24.5 0.036 14.1 2.0 4.5 4 0 0 4 4 4 0 MSP1 EGF domain 1 EGF_3 PF12947.7 KFO97930.1 - 0.046 13.9 54.0 0.099 12.9 5.1 4.7 4 0 0 4 4 4 0 EGF domain BTD PF09270.10 KFO97931.1 - 1.4e-67 226.7 0.0 2.7e-67 225.8 0.0 1.5 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.11 KFO97931.1 - 2e-42 145.4 2.3 4.8e-41 140.9 2.3 2.2 1 1 0 1 1 1 1 LAG1, DNA binding TIG PF01833.24 KFO97931.1 - 0.005 16.9 0.0 0.015 15.4 0.0 1.9 1 0 0 1 1 1 1 IPT/TIG domain Syndecan PF01034.20 KFO97932.1 - 8.2e-25 86.5 0.2 1.2e-24 86.0 0.2 1.2 1 0 0 1 1 1 1 Syndecan domain SYS1 PF09801.9 KFO97933.1 - 5.8e-35 120.5 5.3 6.4e-35 120.4 5.3 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Dysbindin PF04440.16 KFO97934.1 - 7.5e-50 168.9 5.0 8.7e-50 168.7 5.0 1.0 1 0 0 1 1 1 1 Dysbindin (Dystrobrevin binding protein 1) Gpi16 PF04113.14 KFO97935.1 - 5.5e-146 487.3 1.2 6.8e-145 483.7 1.2 1.9 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Cnd3 PF12719.7 KFO97935.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain BC10 PF06726.12 KFO97936.1 - 5.3e-27 93.8 10.2 6.8e-27 93.5 10.2 1.2 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Pkinase_Tyr PF07714.17 KFO97937.1 - 6.7e-93 310.7 0.0 8.6e-93 310.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO97937.1 - 9.1e-47 159.6 0.0 1.6e-46 158.8 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain SH2 PF00017.24 KFO97937.1 - 5.8e-28 96.8 0.1 1.2e-27 95.8 0.1 1.5 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 KFO97937.1 - 0.00013 21.7 0.6 0.00044 20.0 0.1 2.2 3 0 0 3 3 3 1 Variant SH3 domain SH3_1 PF00018.28 KFO97937.1 - 0.00037 20.1 0.2 0.0038 16.8 0.1 2.4 2 0 0 2 2 2 1 SH3 domain Haspin_kinase PF12330.8 KFO97937.1 - 0.0029 16.6 0.0 0.0061 15.6 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain SH3_2 PF07653.17 KFO97937.1 - 0.007 16.0 0.1 0.024 14.3 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain APH PF01636.23 KFO97937.1 - 0.12 12.3 0.0 0.76 9.6 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family UPF0239 PF06783.11 KFO97938.1 - 1.6e-24 85.9 0.0 1.6e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0239) Hormone_2 PF00123.20 KFO97939.1 - 1.5e-14 53.5 0.8 3.4e-14 52.4 0.1 1.9 2 0 0 2 2 2 1 Peptide hormone Ribophorin_II PF05817.14 KFO97940.1 - 5.5e-229 761.9 6.9 6.2e-229 761.7 6.9 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II EMI PF07546.13 KFO97941.1 - 1.5e-16 60.9 5.8 3.9e-16 59.6 5.8 1.8 1 0 0 1 1 1 1 EMI domain DUF5082 PF16888.5 KFO97941.1 - 1.4e-09 38.3 17.4 0.0078 16.5 0.0 6.5 4 2 1 5 5 5 2 Domain of unknown function (DUF5082) DUF1664 PF07889.12 KFO97941.1 - 1.3e-08 34.9 22.6 0.0035 17.4 0.0 7.4 4 2 2 7 7 7 2 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KFO97941.1 - 4.9e-06 26.6 15.4 1.1 9.3 1.9 7.1 3 2 4 7 7 7 1 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 KFO97941.1 - 0.00011 22.4 23.8 0.0087 16.3 2.9 6.6 3 2 2 5 5 5 1 Fibrinogen alpha/beta chain family Apolipoprotein PF01442.18 KFO97941.1 - 0.00015 21.7 14.6 2.5 7.9 0.9 5.8 2 1 2 5 5 5 2 Apolipoprotein A1/A4/E domain CorA PF01544.18 KFO97941.1 - 0.00046 19.6 3.4 0.00046 19.6 3.4 3.8 3 2 1 4 4 4 2 CorA-like Mg2+ transporter protein FlaC_arch PF05377.11 KFO97941.1 - 0.00052 20.4 23.8 6.8 7.2 0.1 10.3 7 3 4 11 11 11 0 Flagella accessory protein C (FlaC) Snapin_Pallidin PF14712.6 KFO97941.1 - 0.00068 20.0 18.8 2.5 8.6 0.0 6.6 4 2 0 5 5 5 1 Snapin/Pallidin HrpB7 PF09486.10 KFO97941.1 - 0.0015 19.0 3.2 4.1 7.8 0.1 5.0 3 1 2 5 5 5 1 Bacterial type III secretion protein (HrpB7) Golgin_A5 PF09787.9 KFO97941.1 - 0.0018 17.8 1.5 0.0018 17.8 1.5 4.1 3 1 2 5 5 5 1 Golgin subfamily A member 5 NPV_P10 PF05531.12 KFO97941.1 - 0.0028 18.1 19.0 9.6 6.8 0.4 8.4 6 1 4 10 10 9 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 KFO97941.1 - 0.0043 16.0 26.7 0.029 13.3 0.1 4.7 2 1 1 5 5 5 2 Spc7 kinetochore protein Fzo_mitofusin PF04799.13 KFO97941.1 - 0.0064 16.1 3.1 0.0064 16.1 3.1 4.9 4 1 1 5 5 4 1 fzo-like conserved region COG2 PF06148.11 KFO97941.1 - 0.024 14.7 17.0 0.3 11.2 1.0 5.9 4 3 0 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 Corona_S2 PF01601.16 KFO97941.1 - 0.033 12.7 6.0 1.5 7.2 0.3 3.8 3 1 1 4 4 4 0 Coronavirus S2 glycoprotein BLOC1_2 PF10046.9 KFO97941.1 - 0.053 13.8 18.4 14 6.1 0.1 7.0 4 2 3 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sugarporin_N PF11471.8 KFO97941.1 - 0.098 12.6 0.1 0.48 10.4 0.0 2.2 2 0 0 2 2 1 0 Maltoporin periplasmic N-terminal extension WXG100 PF06013.12 KFO97941.1 - 0.16 12.2 5.9 11 6.3 0.0 6.3 7 2 1 8 8 6 0 Proteins of 100 residues with WXG TACC_C PF05010.14 KFO97941.1 - 0.2 11.4 18.1 0.057 13.2 1.1 3.7 4 1 1 5 5 5 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal YtxH PF12732.7 KFO97941.1 - 0.23 12.0 0.5 55 4.4 0.1 3.9 4 0 0 4 4 2 0 YtxH-like protein DASH_Dam1 PF08653.10 KFO97941.1 - 0.34 10.7 7.0 55 3.7 0.0 6.0 7 0 0 7 7 7 0 DASH complex subunit Dam1 TPR_MLP1_2 PF07926.12 KFO97941.1 - 0.37 10.8 28.9 0.13 12.3 3.8 6.3 5 2 0 7 7 6 0 TPR/MLP1/MLP2-like protein OmpH PF03938.14 KFO97941.1 - 0.39 11.1 5.5 39 4.6 0.0 4.2 5 1 0 5 5 3 0 Outer membrane protein (OmpH-like) PMEI PF04043.15 KFO97941.1 - 0.81 10.0 7.6 4 7.8 0.1 3.8 3 1 0 4 4 4 0 Plant invertase/pectin methylesterase inhibitor GAS PF13851.6 KFO97941.1 - 1.2 8.4 24.5 0.56 9.5 5.8 5.2 4 2 1 5 5 5 0 Growth-arrest specific micro-tubule binding DUF724 PF05266.14 KFO97941.1 - 1.2 8.9 10.2 7.9 6.3 0.0 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF724) DUF16 PF01519.16 KFO97941.1 - 1.8 9.1 21.2 8.9 6.9 1.6 6.1 4 2 2 6 6 6 0 Protein of unknown function DUF16 RasGAP_C PF03836.15 KFO97941.1 - 1.9 8.7 0.0 1.9 8.7 0.0 4.0 3 2 1 4 4 3 0 RasGAP C-terminus Bacillus_HBL PF05791.11 KFO97941.1 - 2.4 8.0 11.8 1.7 8.5 1.1 4.5 3 1 2 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) Spc24 PF08286.11 KFO97941.1 - 2.9 8.2 19.0 5.1 7.4 0.1 6.3 5 1 1 6 6 6 0 Spc24 subunit of Ndc80 Trimer_CC PF08954.11 KFO97941.1 - 3 7.5 13.3 2.2 7.9 0.2 4.1 5 0 0 5 5 3 0 Trimerisation motif HCMV_UL139 PF12507.8 KFO97941.1 - 4.8 7.6 9.5 5.6 7.4 0.1 4.2 3 2 1 5 5 5 0 Human Cytomegalovirus UL139 protein Jnk-SapK_ap_N PF09744.9 KFO97941.1 - 5 7.3 25.6 1.3 9.2 2.6 5.5 3 1 2 6 6 6 0 JNK_SAPK-associated protein-1 DUF641 PF04859.12 KFO97941.1 - 5.4 7.4 10.7 5.8 7.3 1.0 4.3 3 1 2 5 5 5 0 Plant protein of unknown function (DUF641) LPP PF04728.13 KFO97941.1 - 8.8 6.8 10.3 54 4.3 0.0 5.6 5 1 0 5 5 4 0 Lipoprotein leucine-zipper Homeodomain PF00046.29 KFO97942.1 - 3.7e-35 119.6 14.9 2.4e-08 33.7 0.7 5.4 5 0 0 5 5 5 5 Homeodomain zf_C2H2_ZHX PF18387.1 KFO97942.1 - 1.7e-25 88.4 3.3 2e-25 88.1 0.6 2.2 2 0 0 2 2 2 1 Zinc-fingers and homeoboxes C2H2 finger domain Homez PF11569.8 KFO97942.1 - 2.7e-20 71.6 0.1 5.8e-10 38.5 0.0 5.1 5 0 0 5 5 5 3 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 KFO97942.1 - 3e-20 71.8 2.1 0.0027 17.6 0.1 5.6 5 0 0 5 5 5 5 Homeobox KN domain Auxin_canalis PF05703.11 KFO97942.1 - 0.098 12.6 2.0 6.4 6.6 0.0 2.8 3 0 0 3 3 3 0 Auxin canalisation PI-PLC-X PF00388.19 KFO97943.1 - 1e-65 219.8 0.4 2.1e-65 218.7 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain SH2 PF00017.24 KFO97943.1 - 8.7e-48 160.3 0.1 2.2e-24 85.4 0.0 3.0 2 0 0 2 2 2 2 SH2 domain PI-PLC-Y PF00387.19 KFO97943.1 - 1.9e-39 134.6 0.0 4.5e-39 133.3 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain SH3_1 PF00018.28 KFO97943.1 - 4.4e-16 58.2 0.6 1.2e-15 56.8 0.6 1.8 1 0 0 1 1 1 1 SH3 domain C2 PF00168.30 KFO97943.1 - 1.5e-14 54.1 0.1 5.7e-14 52.3 0.0 2.0 2 0 0 2 2 2 1 C2 domain PH PF00169.29 KFO97943.1 - 7.9e-12 45.6 0.3 0.0094 16.4 0.1 4.1 4 0 0 4 4 3 3 PH domain SH3_9 PF14604.6 KFO97943.1 - 2.8e-10 39.9 0.1 2.8e-10 39.9 0.1 2.2 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.17 KFO97943.1 - 6.6e-09 35.3 0.1 1.5e-08 34.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH_12 PF16457.5 KFO97943.1 - 0.00016 22.2 0.0 0.00048 20.7 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain GDPD PF03009.17 KFO97943.1 - 0.00038 20.3 0.0 0.0016 18.2 0.0 1.9 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family EF-hand_6 PF13405.6 KFO97943.1 - 0.12 12.4 0.0 2.9 8.1 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain Topoisom_I PF01028.20 KFO97944.1 - 3.3e-103 343.9 3.6 3.3e-103 343.9 3.6 2.7 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KFO97944.1 - 2.1e-101 337.8 7.8 2.1e-101 337.8 7.8 5.3 4 1 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KFO97944.1 - 1.3e-33 114.8 0.5 1.3e-33 114.8 0.5 3.0 2 0 0 2 2 2 1 C-terminal topoisomerase domain C2 PF00168.30 KFO97945.1 - 3.5e-15 56.1 0.0 6e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain Ion_trans_2 PF07885.16 KFO97946.1 - 3.1e-36 123.2 16.8 4.3e-18 65.1 1.3 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 KFO97946.1 - 2.4e-05 23.7 13.2 0.0044 16.3 6.6 2.2 2 0 0 2 2 2 2 Ion transport protein IRK PF01007.20 KFO97946.1 - 1.3 8.9 6.7 1 9.2 0.1 2.5 2 1 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain Reticulon PF02453.17 KFO97946.1 - 3 7.8 5.8 2.4 8.1 1.0 2.6 3 0 0 3 3 3 0 Reticulon DUF2101 PF09874.9 KFO97946.1 - 4.8 6.8 6.9 33 4.1 0.1 2.5 2 1 1 3 3 3 0 Predicted membrane protein (DUF2101) IGFBP PF00219.18 KFO97947.1 - 3.1e-10 40.5 20.1 3.1e-10 40.5 20.1 2.7 2 1 0 2 2 2 1 Insulin-like growth factor binding protein VWC PF00093.18 KFO97947.1 - 1.3e-05 25.5 2.4 1.3e-05 25.5 2.4 3.1 3 0 0 3 3 3 1 von Willebrand factor type C domain Secapin PF17521.2 KFO97947.1 - 0.53 10.1 6.6 0.87 9.4 6.6 1.3 1 0 0 1 1 1 0 Honey bee peptides A_deaminase PF00962.22 KFO97948.1 - 2.3e-95 319.7 0.0 2.6e-95 319.5 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Phage_spike_2 PF18781.1 KFO97948.1 - 0.18 11.8 0.0 0.44 10.6 0.0 1.6 1 0 0 1 1 1 0 Phage spike trimer PKI PF02827.16 KFO97949.1 - 2e-19 69.5 0.2 2.2e-19 69.4 0.2 1.0 1 0 0 1 1 1 1 cAMP-dependent protein kinase inhibitor AAR2 PF05282.11 KFO97950.1 - 1e-56 192.9 0.0 1.1e-56 192.8 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein Alginate_lyase PF05426.12 KFO97950.1 - 0.0097 15.5 0.1 0.014 15.0 0.1 1.2 1 0 0 1 1 1 1 Alginate lyase 4_1_CTD PF05902.13 KFO97951.1 - 9.7e-33 112.4 3.4 9.7e-33 112.4 3.4 3.0 3 1 0 3 3 3 1 4.1 protein C-terminal domain (CTD) FERM_C PF09380.10 KFO97951.1 - 5.8e-25 87.5 0.0 1.1e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KFO97951.1 - 1.8e-21 75.8 0.3 1.2e-20 73.2 0.2 2.5 3 0 0 3 3 3 1 FERM N-terminal domain SAB PF04382.13 KFO97951.1 - 3.9e-21 74.9 2.5 1.3e-20 73.2 2.5 2.0 1 0 0 1 1 1 1 SAB domain FERM_M PF00373.18 KFO97951.1 - 1.9e-20 73.4 0.0 6e-20 71.8 0.0 1.9 1 0 0 1 1 1 1 FERM central domain FA PF08736.11 KFO97951.1 - 1.7e-18 66.4 2.6 6.3e-18 64.6 2.6 2.1 1 0 0 1 1 1 1 FERM adjacent (FA) RRM_1 PF00076.22 KFO97952.1 - 5.9e-14 51.6 0.0 9e-14 51.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFO97952.1 - 0.0001 22.3 0.0 0.00026 21.0 0.0 1.7 1 0 0 1 1 1 1 RNA binding motif HMG_box PF00505.19 KFO97953.1 - 6.2e-11 42.6 0.0 1.3e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFO97953.1 - 2.3e-09 37.7 0.0 4.4e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.13 KFO97953.1 - 0.014 15.9 0.3 0.022 15.4 0.3 1.4 1 0 0 1 1 1 0 YABBY protein IMUP PF15761.5 KFO97953.1 - 0.023 15.4 9.1 0.023 15.4 9.1 1.6 2 0 0 2 2 2 0 Immortalisation up-regulated protein Mitofilin PF09731.9 KFO97953.1 - 0.32 9.8 4.6 0.39 9.5 4.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Glyco_hydro_47 PF01532.20 KFO97954.1 - 4.6e-115 385.1 0.0 5.9e-115 384.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF3689 PF12463.8 KFO97955.1 - 8.1e-142 472.1 15.6 1.4e-141 471.3 15.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3689) Myosin_head PF00063.21 KFO97956.1 - 9.4e-293 972.6 1.4 9.4e-293 972.6 1.4 3.4 4 0 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KFO97956.1 - 2.1e-161 539.1 254.9 3.9e-161 538.3 254.9 1.4 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 KFO97956.1 - 6.6e-14 51.5 7.2 1.6e-13 50.3 7.2 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Filament PF00038.21 KFO97956.1 - 4e-09 36.5 218.3 1.7e-06 27.9 36.5 9.8 1 1 7 8 8 8 4 Intermediate filament protein Sec2p PF06428.11 KFO97956.1 - 0.0013 18.6 6.6 0.0013 18.6 6.6 16.9 1 1 13 15 15 15 2 GDP/GTP exchange factor Sec2p IQ PF00612.27 KFO97956.1 - 0.023 14.5 1.4 0.17 11.8 0.3 2.8 2 0 0 2 2 2 0 IQ calmodulin-binding motif DUF1664 PF07889.12 KFO97956.1 - 0.054 13.5 140.7 0.18 11.9 3.2 13.5 2 2 9 13 13 13 0 Protein of unknown function (DUF1664) AAA_22 PF13401.6 KFO97956.1 - 0.095 13.0 0.0 0.095 13.0 0.0 6.9 2 1 2 6 6 6 0 AAA domain HutP PF09021.11 KFO97956.1 - 0.11 12.8 2.7 0.93 9.8 2.7 2.7 1 0 0 1 1 1 0 HutP AAA_16 PF13191.6 KFO97956.1 - 0.56 10.6 0.0 0.56 10.6 0.0 6.9 3 1 1 4 4 4 0 AAA ATPase domain DUF1072 PF06380.11 KFO97957.1 - 0.062 13.2 2.4 0.1 12.5 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1072) CAAX_1 PF15895.5 KFO97957.1 - 0.91 9.4 6.8 0.97 9.3 6.8 1.1 1 0 0 1 1 1 0 CAAX box cerebral protein 1 GSH_synth_ATP PF03917.17 KFO97959.1 - 7e-126 420.0 0.0 7.9e-126 419.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KFO97959.1 - 1.4e-28 99.3 0.2 3.2e-28 98.2 0.1 1.7 2 0 0 2 2 2 1 Eukaryotic glutathione synthase AMP-binding PF00501.28 KFO97960.1 - 1.6e-94 316.9 0.0 1.9e-94 316.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFO97960.1 - 1.2e-23 83.8 0.0 2.4e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KFO97960.1 - 0.0011 18.8 0.2 0.0033 17.3 0.2 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Y_phosphatase PF00102.27 KFO97961.1 - 3.6e-148 491.5 1.3 1.5e-81 273.5 0.0 2.5 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 KFO97961.1 - 4.2e-29 100.7 2.1 2.6e-11 43.7 0.0 5.5 4 1 1 5 5 5 4 Fibronectin type III domain MAM PF00629.23 KFO97961.1 - 3.8e-24 85.4 0.0 1e-23 84.1 0.0 1.8 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu DSPc PF00782.20 KFO97961.1 - 4.7e-09 36.2 0.1 0.0017 18.2 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFO97961.1 - 7.3e-05 22.8 0.0 0.024 14.6 0.0 2.3 2 0 0 2 2 2 2 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFO97961.1 - 0.00013 22.1 0.0 0.8 9.8 0.0 2.7 2 0 0 2 2 2 2 Inositol hexakisphosphate Amnionless PF14828.6 KFO97961.1 - 0.016 14.0 0.2 0.028 13.2 0.2 1.3 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 KFO97961.1 - 0.025 15.4 0.0 0.061 14.2 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PTP_tm PF18861.1 KFO97961.1 - 0.025 14.6 0.0 0.063 13.3 0.0 1.7 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J I-set PF07679.16 KFO97961.1 - 0.043 13.9 0.0 0.098 12.7 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_2 PF13895.6 KFO97961.1 - 0.058 13.7 1.2 0.17 12.2 0.1 2.5 2 0 0 2 2 2 0 Immunoglobulin domain ig PF00047.25 KFO97961.1 - 0.087 13.0 0.5 0.22 11.7 0.1 1.9 2 0 0 2 2 1 0 Immunoglobulin domain Yae1_N PF09811.9 KFO97962.1 - 1.9e-16 59.4 61.2 0.25 11.1 1.7 6.0 1 1 1 2 2 2 1 Essential protein Yae1, N terminal HECT PF00632.25 KFO97963.1 - 1.8e-98 329.8 0.2 2.4e-98 329.4 0.2 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KFO97963.1 - 3.1e-45 151.9 19.5 7.4e-14 51.5 0.9 4.7 4 0 0 4 4 4 4 WW domain C2 PF00168.30 KFO97963.1 - 1.1e-13 51.4 0.5 2.7e-13 50.1 0.5 1.7 1 0 0 1 1 1 1 C2 domain CDC27 PF09507.10 KFO97963.1 - 0.69 9.2 5.4 1.1 8.6 5.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Robl_LC7 PF03259.17 KFO97964.1 - 8e-26 89.6 0.0 8.8e-26 89.5 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 KFO97964.1 - 5e-05 23.1 0.0 5.9e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 UPF0176_N PF17773.1 KFO97964.1 - 0.036 14.4 0.0 0.041 14.2 0.0 1.1 1 0 0 1 1 1 0 UPF0176 acylphosphatase like domain Atg8 PF02991.16 KFO97965.1 - 2.9e-45 152.7 0.4 3.2e-45 152.6 0.4 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KFO97965.1 - 2.5e-06 27.8 0.0 3.1e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Cytochrom_B559a PF00284.20 KFO97965.1 - 0.13 12.1 0.1 0.38 10.5 0.1 1.8 1 1 1 2 2 2 0 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit Peptidase_M10 PF00413.24 KFO97966.1 - 1.4e-62 210.2 0.2 2.7e-62 209.3 0.2 1.5 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 KFO97966.1 - 5.3e-54 179.9 20.2 9.1e-16 57.5 0.9 4.6 4 0 0 4 4 4 4 Hemopexin DUF3377 PF11857.8 KFO97966.1 - 2.6e-29 101.0 1.8 4.1e-29 100.3 1.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) PG_binding_1 PF01471.18 KFO97966.1 - 1.3e-10 41.4 0.1 2.6e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.24 KFO97966.1 - 0.0002 21.0 1.4 0.43 10.2 0.1 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) DUF4293 PF14126.6 KFO97966.1 - 0.0028 17.9 0.1 0.0048 17.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4293) Peptidase_M66 PF10462.9 KFO97966.1 - 0.041 12.8 0.4 0.066 12.2 0.4 1.2 1 0 0 1 1 1 0 Peptidase M66 Metallopep PF12044.8 KFO97966.1 - 0.048 12.3 0.1 0.072 11.7 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_3 PF13582.6 KFO97966.1 - 0.058 13.9 0.2 0.18 12.3 0.3 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 KFO97966.1 - 0.076 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M54 DUF4953 PF16313.5 KFO97966.1 - 0.095 11.9 0.2 0.17 11.1 0.2 1.3 1 0 0 1 1 1 0 Met-zincin eIF-6 PF01912.18 KFO97967.1 - 1.3e-59 200.9 0.2 7.5e-59 198.4 0.1 1.8 2 0 0 2 2 2 1 eIF-6 family FAM83 PF07894.12 KFO97968.1 - 9.5e-102 340.2 0.0 2.1e-101 339.1 0.0 1.5 2 0 0 2 2 2 1 FAM83 A-H PLDc_2 PF13091.6 KFO97968.1 - 0.0035 17.2 0.0 0.0058 16.5 0.0 1.4 1 0 0 1 1 1 1 PLD-like domain Ubiq_cyt_C_chap PF03981.12 KFO97969.1 - 3.3e-43 147.2 0.1 4.9e-43 146.6 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone TGF_beta PF00019.20 KFO97970.1 - 3.5e-33 114.7 0.7 6.8e-33 113.8 0.7 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFO97970.1 - 1.9e-18 67.2 0.0 3.2e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 TGF-beta propeptide Rootletin PF15035.6 KFO97971.1 - 5.7e-39 134.1 12.7 5.7e-39 134.1 12.7 17.9 2 1 14 16 16 16 1 Ciliary rootlet component, centrosome cohesion BLOC1_2 PF10046.9 KFO97971.1 - 0.0033 17.7 3.6 0.0033 17.7 3.6 23.2 12 6 12 27 27 27 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 MarR PF01047.22 KFO97971.1 - 0.0065 16.4 4.5 5 7.1 0.2 4.8 2 1 2 4 4 4 2 MarR family DUF4687 PF15747.5 KFO97971.1 - 0.039 14.4 0.3 0.1 13.1 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4687) COPIIcoated_ERV PF07970.12 KFO97972.1 - 1e-94 316.5 0.9 1.2e-94 316.3 0.9 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KFO97972.1 - 2.5e-12 47.0 0.1 8e-12 45.3 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Glyco_transf_29 PF00777.18 KFO97973.1 - 6.4e-72 242.2 0.0 7.6e-72 241.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) G_glu_transpept PF01019.21 KFO97973.1 - 0.11 11.3 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase Ferlin_C PF16165.5 KFO97974.1 - 7.7e-24 84.4 6.8 8.4e-24 84.3 6.8 1.0 1 0 0 1 1 1 1 Ferlin C-terminus DUF2628 PF10947.8 KFO97974.1 - 0.018 15.4 2.9 0.018 15.4 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) Synaptobrevin PF00957.21 KFO97974.1 - 5.1 6.9 5.5 6 6.7 5.5 1.1 1 0 0 1 1 1 0 Synaptobrevin Ferlin_C PF16165.5 KFO97975.1 - 1.2e-19 70.8 2.1 1.5e-09 37.9 0.3 2.1 1 1 1 2 2 2 2 Ferlin C-terminus C2 PF00168.30 KFO97976.1 - 3.5e-21 75.4 0.0 5.3e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 C2 domain Copine PF07002.16 KFO97977.1 - 7.6e-88 293.6 0.0 1.1e-87 293.1 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 KFO97977.1 - 6.4e-24 84.2 0.0 3.7e-12 46.4 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 KFO97977.1 - 7.4e-06 26.2 0.0 1.2e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 KFO97977.1 - 0.012 15.8 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain TLV_coat PF00429.19 KFO97978.1 - 0.0041 15.9 0.3 0.0045 15.7 0.3 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) DUF4763 PF15960.5 KFO97978.1 - 0.045 13.1 0.1 0.045 13.1 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Lectin_N PF03954.14 KFO97978.1 - 0.098 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Aminotran_5 PF00266.19 KFO97979.1 - 1.1e-89 301.0 0.0 1.3e-89 300.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFO97979.1 - 5.4e-10 39.0 0.0 8.1e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KFO97979.1 - 0.0024 17.3 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family B12-binding PF02310.19 KFO97979.1 - 0.013 15.6 0.2 0.39 10.8 0.0 2.6 3 0 0 3 3 3 0 B12 binding domain Pyridoxal_deC PF00282.19 KFO97979.1 - 0.038 12.7 0.0 0.066 11.9 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 KFO97979.1 - 0.15 10.6 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Romo1 PF10247.9 KFO97980.1 - 2.8e-26 91.7 22.0 3.3e-26 91.4 22.0 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 KFO97980.1 - 0.0082 16.5 9.8 0.0095 16.3 9.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family RRM_1 PF00076.22 KFO97981.1 - 3.5e-31 106.8 0.0 4.8e-24 84.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KFO97981.1 - 6e-27 94.6 0.3 1.8e-26 93.1 0.3 1.8 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 KFO97981.1 - 0.0015 18.3 0.0 0.014 15.3 0.0 2.5 2 1 0 2 2 2 1 Occluded RNA-recognition motif DUF1866 PF08952.11 KFO97981.1 - 0.069 13.0 0.0 6.4 6.6 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1866) RRM_5 PF13893.6 KFO97981.1 - 0.13 11.8 0.0 0.35 10.5 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.14 KFO97981.1 - 0.86 7.8 19.5 1.1 7.4 19.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KFO97981.1 - 1.4 7.6 9.6 2 7.1 9.6 1.2 1 0 0 1 1 1 0 Presenilin SOBP PF15279.6 KFO97981.1 - 9.8 6.7 6.8 19 5.8 6.8 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein DUF3776 PF12618.8 KFO97982.1 - 1.5e-26 92.8 19.9 1.5e-26 92.8 19.9 4.6 4 1 0 4 4 3 1 Protein of unknown function (DUF3776) Tudor_3 PF18115.1 KFO97982.1 - 3.5e-15 55.6 1.0 3.5e-13 49.2 0.3 3.0 3 0 0 3 3 3 1 DNA repair protein Crb2 Tudor domain PHD PF00628.29 KFO97982.1 - 2.7e-06 27.2 12.4 1.1e-05 25.2 12.4 2.2 1 0 0 1 1 1 1 PHD-finger Tudor_2 PF18104.1 KFO97982.1 - 1.1e-05 24.9 0.3 2.7e-05 23.7 0.3 1.7 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain MBT PF02820.18 KFO97982.1 - 0.00028 21.2 0.6 0.0025 18.2 0.1 2.7 3 0 0 3 3 3 1 mbt repeat DUF4537 PF15057.6 KFO97982.1 - 0.00038 20.5 0.3 0.0013 18.8 0.3 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4537) Tudor-knot PF11717.8 KFO97982.1 - 0.0022 17.9 2.7 0.011 15.7 1.4 2.7 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain LBR_tudor PF09465.10 KFO97982.1 - 0.011 15.5 0.0 0.027 14.2 0.0 1.7 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Rad9_Rad53_bind PF08605.10 KFO97982.1 - 0.026 14.7 3.4 0.58 10.3 0.1 3.2 4 0 0 4 4 4 0 Fungal Rad9-like Rad53-binding Agenet PF05641.12 KFO97982.1 - 0.044 14.3 2.7 1.5 9.3 0.2 3.0 2 0 0 2 2 2 0 Agenet domain zf-C2H2 PF00096.26 KFO97982.1 - 5.8 7.6 11.7 0.66 10.6 6.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type SH2 PF00017.24 KFO97983.1 - 5.2e-22 77.7 0.1 7.6e-22 77.2 0.1 1.2 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFO97983.1 - 0.058 13.0 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 SH3 domain SH3_9 PF14604.6 KFO97983.1 - 0.064 13.1 0.0 0.72 9.8 0.0 2.5 2 0 0 2 2 2 0 Variant SH3 domain SH3_2 PF07653.17 KFO97983.1 - 0.14 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Ndr PF03096.14 KFO97984.1 - 4.5e-125 416.0 0.0 5.3e-125 415.8 0.0 1.0 1 0 0 1 1 1 1 Ndr family Abhydrolase_1 PF00561.20 KFO97984.1 - 1.5e-05 24.8 0.0 0.00025 20.8 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Rap_GAP PF02145.15 KFO97985.1 - 0.046 13.3 0.0 1.6 8.2 0.0 2.8 3 0 0 3 3 3 0 Rap/ran-GAP SNF2_N PF00176.23 KFO97986.1 - 5.9e-63 212.7 2.4 9.5e-63 212.0 2.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 KFO97986.1 - 4e-25 87.5 3.5 2.8e-13 49.5 0.7 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KFO97986.1 - 1.1e-16 61.1 0.0 3.7e-16 59.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFO97986.1 - 1.4e-07 31.7 0.1 7e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CHDCT2 PF08074.11 KFO97986.1 - 1.6e-05 25.2 0.8 0.37 11.0 0.0 3.7 3 0 0 3 3 3 2 CHDCT2 (NUC038) domain DEAD PF00270.29 KFO97986.1 - 0.00031 20.5 0.0 0.00061 19.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KFO97986.1 - 0.0059 15.8 0.1 0.036 13.2 0.1 2.2 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 BRK PF07533.16 KFO97986.1 - 0.042 13.5 1.1 0.23 11.1 0.2 2.4 2 0 0 2 2 2 0 BRK domain DUF3437 PF11919.8 KFO97986.1 - 0.13 12.2 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) RB_A PF01858.17 KFO97987.1 - 8.2e-80 267.3 4.7 2.2e-79 265.9 0.7 2.8 3 0 0 3 3 3 1 Retinoblastoma-associated protein A domain RB_B PF01857.20 KFO97987.1 - 6.2e-55 184.8 0.4 2.4e-54 182.9 0.4 2.1 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 KFO97987.1 - 1.4e-40 138.0 1.4 1.4e-40 138.0 1.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3452) Rb_C PF08934.10 KFO97987.1 - 5.6e-06 26.2 0.4 1.2e-05 25.1 0.4 1.6 1 0 0 1 1 1 1 Rb C-terminal domain Phage_F PF02305.17 KFO97987.1 - 0.035 12.9 0.1 0.054 12.3 0.1 1.2 1 0 0 1 1 1 0 Capsid protein (F protein) eIF-3c_N PF05470.12 KFO97987.1 - 0.94 7.7 6.1 3.7 5.7 6.1 1.9 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus HD PF01966.22 KFO97988.1 - 2e-15 57.1 0.0 6.2e-15 55.5 0.0 1.9 2 0 0 2 2 2 1 HD domain PDEase_I PF00233.19 KFO97988.1 - 0.0076 16.0 0.1 0.028 14.1 0.0 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase TLD PF07534.16 KFO97989.1 - 3.4e-36 124.5 0.0 3.9e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 TLD PIG-U PF06728.13 KFO97990.1 - 5.5e-105 351.6 49.4 6.2e-105 351.4 49.4 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U RVT_1 PF00078.27 KFO97991.1 - 6.8e-25 87.9 0.0 8.9e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 KFO97991.1 - 7.9e-07 28.8 0.1 1.4e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase thumb domain 7tm_4 PF13853.6 KFO97992.1 - 3.8e-27 95.8 6.9 1.8e-26 93.5 6.9 1.8 1 1 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO97992.1 - 2e-14 53.6 6.6 3e-14 53.0 6.6 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TMEM18 PF14770.6 KFO97992.1 - 0.014 15.4 1.6 0.017 15.1 0.2 1.8 2 0 0 2 2 2 0 Transmembrane protein 18 Reticulon PF02453.17 KFO97992.1 - 0.023 14.7 0.4 0.023 14.7 0.4 2.4 2 1 0 2 2 2 0 Reticulon vMSA PF00695.19 KFO97992.1 - 1.9 7.5 7.8 2.6 7.1 7.8 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Patched PF02460.18 KFO97993.1 - 1.3e-95 321.2 21.8 2.3e-95 320.4 21.8 1.3 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 KFO97993.1 - 2e-19 69.9 1.6 2e-19 69.9 1.6 2.5 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation AhpC-TSA PF00578.21 KFO97994.1 - 5e-34 116.9 0.0 6.3e-34 116.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFO97994.1 - 5.4e-12 45.7 0.0 6.7e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KFO97994.1 - 7.9e-11 41.6 0.1 2.2e-10 40.2 0.1 1.8 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin 4HBT PF03061.22 KFO97995.1 - 3.8e-09 36.8 0.0 0.0016 18.7 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily Acetyltransf_1 PF00583.25 KFO97996.1 - 8.3e-17 61.5 0.1 1e-16 61.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFO97996.1 - 2.5e-08 34.2 0.0 4.3e-08 33.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFO97996.1 - 7e-06 26.0 0.0 8.7e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFO97996.1 - 0.00091 19.1 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KFO97996.1 - 0.0012 19.6 0.0 0.0015 19.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFO97996.1 - 0.019 15.1 0.0 0.13 12.4 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain ApoO PF09769.9 KFO97997.1 - 8.6e-36 122.8 0.0 9.7e-36 122.6 0.0 1.0 1 0 0 1 1 1 1 Apolipoprotein O Kelch_1 PF01344.25 KFO97998.1 - 1.1e-40 137.0 7.6 3e-11 42.7 0.1 5.4 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 KFO97998.1 - 2.3e-34 116.5 4.8 1.5e-08 34.6 0.2 6.2 3 2 2 5 5 5 5 Kelch motif BTB PF00651.31 KFO97998.1 - 1.5e-23 83.2 1.9 1.5e-23 83.2 1.9 2.2 3 0 0 3 3 3 1 BTB/POZ domain Kelch_4 PF13418.6 KFO97998.1 - 1.6e-20 72.8 1.3 0.0049 16.9 0.0 5.9 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KFO97998.1 - 7.5e-18 64.4 0.8 0.00014 22.1 0.1 5.7 5 2 0 5 5 5 4 Galactose oxidase, central domain BACK PF07707.15 KFO97998.1 - 5.8e-16 58.5 0.9 8.1e-16 58.0 0.1 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 KFO97998.1 - 2.4e-14 52.7 11.4 0.0012 18.8 0.0 6.1 6 1 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 KFO97998.1 - 1.8e-08 34.2 8.6 0.062 13.3 0.0 5.3 5 0 0 5 5 5 4 Kelch motif eIF2_C PF09173.11 KFO97999.1 - 5.9e-37 125.8 2.2 6.5e-37 125.7 0.5 2.0 2 0 0 2 2 2 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KFO97999.1 - 4.6e-23 81.8 1.1 4.1e-22 78.7 1.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KFO97999.1 - 5.9e-13 49.0 0.3 1.7e-12 47.5 0.3 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KFO97999.1 - 0.0031 17.4 0.4 0.025 14.5 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KFO97999.1 - 0.0032 17.5 0.0 0.0067 16.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KFO97999.1 - 0.014 15.4 0.1 0.028 14.4 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain G-alpha PF00503.20 KFO97999.1 - 0.12 11.5 0.1 0.83 8.7 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit Dynamin_N PF00350.23 KFO97999.1 - 0.13 12.3 0.2 0.53 10.3 0.2 2.0 1 1 0 1 1 1 0 Dynamin family Zfx_Zfy_act PF04704.13 KFO98000.1 - 1.2e-151 504.5 18.7 1.2e-151 504.5 18.7 1.6 2 0 0 2 2 2 1 Zfx / Zfy transcription activation region zf-C2H2 PF00096.26 KFO98000.1 - 1.7e-41 138.4 117.1 1e-05 25.7 2.1 13.4 13 0 0 13 13 13 12 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO98000.1 - 2.5e-38 128.8 121.9 2.7e-08 33.9 1.2 13.7 14 0 0 14 14 13 12 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFO98000.1 - 2.7e-32 108.7 111.3 0.00016 22.2 0.9 13.4 13 0 0 13 13 13 13 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFO98000.1 - 2e-25 88.2 106.5 4.4e-07 29.5 5.8 12.6 12 1 0 12 12 12 8 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFO98000.1 - 5.4e-12 45.7 74.7 0.028 14.7 0.1 12.3 13 0 0 13 13 12 7 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 KFO98000.1 - 3.8e-08 34.0 48.3 0.028 15.2 2.4 7.3 4 2 3 7 7 7 5 zinc-ribbon family zf-BED PF02892.15 KFO98000.1 - 0.0049 16.8 2.5 0.0049 16.8 2.5 10.2 4 3 7 11 11 11 5 BED zinc finger zf-C2H2_3rep PF18868.1 KFO98000.1 - 0.0097 16.6 47.2 0.17 12.6 5.6 7.8 1 1 3 6 6 6 3 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 KFO98000.1 - 0.021 14.6 0.2 0.021 14.6 0.2 10.1 13 0 0 13 13 13 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFO98000.1 - 0.022 14.8 3.3 0.022 14.8 3.3 10.1 11 0 0 11 11 10 0 C2H2-type zinc finger zf-met PF12874.7 KFO98000.1 - 0.15 12.5 0.0 0.15 12.5 0.0 11.4 12 1 1 13 13 12 0 Zinc-finger of C2H2 type zf-RING_7 PF02591.15 KFO98000.1 - 2.6 8.3 11.8 27 5.1 0.1 5.8 5 0 0 5 5 5 0 C4-type zinc ribbon domain Solute_trans_a PF03619.16 KFO98001.1 - 4.5e-40 137.8 20.7 5.5e-40 137.6 20.7 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha AmiS_UreI PF02293.15 KFO98001.1 - 0.0015 18.6 2.2 0.0015 18.6 2.2 2.1 2 0 0 2 2 2 1 AmiS/UreI family transporter BCDHK_Adom3 PF10436.9 KFO98002.1 - 6e-50 169.2 0.0 9e-50 168.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KFO98002.1 - 4.9e-13 49.6 0.0 7.7e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFO98002.1 - 0.0088 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CTP_transf_like PF01467.26 KFO98003.1 - 5.3e-32 111.0 0.4 1e-31 110.1 0.0 1.6 2 0 0 2 2 2 1 Cytidylyltransferase-like Lipoprotein_6 PF01441.19 KFO98003.1 - 0.073 13.1 1.9 0.12 12.4 1.9 1.2 1 0 0 1 1 1 0 Lipoprotein YtxH PF12732.7 KFO98003.1 - 0.13 12.8 1.9 0.27 11.8 1.9 1.5 1 0 0 1 1 1 0 YtxH-like protein DNA_pol_B PF00136.21 KFO98004.1 - 3.4e-130 434.8 0.8 4.6e-130 434.4 0.8 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KFO98004.1 - 4.8e-57 193.6 0.0 1.5e-56 192.0 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.10 KFO98004.1 - 5.1e-53 179.6 8.3 9.3e-53 178.7 8.3 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_alpha_N PF12254.8 KFO98004.1 - 3.7e-17 62.2 13.5 1.6e-16 60.1 11.4 3.1 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal DUF1744 PF08490.12 KFO98004.1 - 0.00022 19.9 0.7 0.00075 18.2 0.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1744) DNA_pol_B_2 PF03175.13 KFO98004.1 - 0.0019 17.2 0.0 0.0074 15.2 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral Ig_2 PF13895.6 KFO98005.1 - 8.2e-07 29.3 0.0 9.1e-07 29.1 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFO98005.1 - 9.6e-06 25.6 0.0 1.1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO98005.1 - 2.6e-05 24.7 0.1 3.2e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFO98005.1 - 0.00045 20.4 0.2 0.00069 19.8 0.1 1.4 1 1 1 2 2 2 1 Immunoglobulin V-set domain ig PF00047.25 KFO98005.1 - 0.00098 19.2 0.1 0.0012 18.9 0.1 1.4 1 1 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 KFO98005.1 - 0.0013 18.2 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFO98005.1 - 0.012 15.6 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Frizzled PF01534.17 KFO98006.1 - 1.2e-121 405.8 17.2 1.5e-121 405.4 17.2 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 KFO98006.1 - 7.7e-28 97.3 8.1 1.5e-27 96.4 8.1 1.5 1 0 0 1 1 1 1 Fz domain DUF898 PF05987.13 KFO98006.1 - 0.027 13.5 0.2 0.027 13.5 0.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) Glyco_transf_64 PF09258.10 KFO98007.1 - 2.6e-101 338.0 0.1 4.4e-101 337.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 KFO98007.1 - 8.4e-56 189.4 0.0 1.6e-55 188.5 0.0 1.5 1 0 0 1 1 1 1 Exostosin family DUF812 PF05667.11 KFO98007.1 - 0.017 14.0 1.2 0.027 13.4 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Jnk-SapK_ap_N PF09744.9 KFO98007.1 - 0.018 15.3 3.0 0.036 14.3 3.0 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ADIP PF11559.8 KFO98007.1 - 0.022 14.9 7.6 0.037 14.1 7.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 KFO98007.1 - 0.029 14.4 2.4 0.062 13.3 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 KFO98007.1 - 0.042 14.4 4.4 0.096 13.2 4.4 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 KFO98007.1 - 0.066 13.4 5.3 0.13 12.5 5.3 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain EzrA PF06160.12 KFO98007.1 - 0.19 9.9 4.3 0.3 9.2 4.3 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA THOC7 PF05615.13 KFO98007.1 - 0.19 12.0 5.9 0.092 13.0 3.3 1.7 2 0 0 2 2 2 0 Tho complex subunit 7 Noelin-1 PF12308.8 KFO98007.1 - 0.26 11.3 2.0 0.55 10.2 2.0 1.5 1 0 0 1 1 1 0 Neurogenesis glycoprotein CAMSAP_CC1 PF17095.5 KFO98007.1 - 0.38 10.7 1.6 0.73 9.7 1.6 1.4 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin Tropomyosin_1 PF12718.7 KFO98007.1 - 0.39 10.9 6.5 0.76 9.9 6.5 1.4 1 0 0 1 1 1 0 Tropomyosin like TMPIT PF07851.13 KFO98007.1 - 0.46 9.7 2.9 0.97 8.6 2.9 1.5 1 0 0 1 1 1 0 TMPIT-like protein TPR_MLP1_2 PF07926.12 KFO98007.1 - 0.47 10.5 12.3 0.061 13.4 8.3 1.5 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein Cortex-I_coil PF09304.10 KFO98007.1 - 1.2 9.4 8.3 0.64 10.3 5.4 1.9 2 0 0 2 2 2 0 Cortexillin I, coiled coil Cluap1 PF10234.9 KFO98007.1 - 1.4 8.3 5.4 2.1 7.7 5.4 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Spc7 PF08317.11 KFO98007.1 - 1.4 7.7 7.7 2.6 6.8 7.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.14 KFO98007.1 - 1.5 8.6 4.4 2.6 7.8 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DivIC PF04977.15 KFO98007.1 - 8.5 6.2 7.5 8.2 6.3 5.2 2.0 1 1 1 2 2 2 0 Septum formation initiator Lactamase_B_6 PF16661.5 KFO98008.1 - 4.6e-15 55.6 0.2 3.5e-14 52.7 0.1 2.3 2 1 1 3 3 3 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 KFO98008.1 - 6.6e-07 29.6 0.0 1.3e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain Beta_lactamase3 PF17030.5 KFO98008.1 - 0.0087 15.3 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Putative beta-lactamase-like family HNF-1_N PF04814.13 KFO98009.1 - 1e-62 212.2 3.4 2.2e-62 211.1 3.4 1.6 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Homeodomain PF00046.29 KFO98009.1 - 2.1e-10 40.3 1.7 8.1e-10 38.4 0.1 2.8 3 1 0 3 3 3 1 Homeodomain Homeobox_KN PF05920.11 KFO98009.1 - 3.1e-05 23.8 0.7 0.0023 17.8 0.1 2.9 2 1 0 2 2 2 1 Homeobox KN domain HTH_37 PF13744.6 KFO98009.1 - 0.001 19.0 0.4 0.001 19.0 0.4 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 KFO98009.1 - 0.0029 17.6 0.4 0.048 13.7 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 KFO98009.1 - 0.003 17.6 0.1 0.0068 16.4 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_24 PF13412.6 KFO98009.1 - 0.013 15.1 0.2 0.059 12.9 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding AbiJ_NTD3 PF18860.1 KFO98009.1 - 0.013 15.0 0.3 0.25 10.9 0.1 2.5 3 0 0 3 3 3 0 AbiJ N-terminal domain 3 HTH_31 PF13560.6 KFO98009.1 - 0.018 15.4 1.9 0.076 13.4 0.1 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain DUF494 PF04361.13 KFO98009.1 - 0.021 14.7 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF494) Pex14_N PF04695.13 KFO98009.1 - 0.055 14.1 3.4 0.078 13.6 1.2 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NOC3p PF07540.11 KFO98009.1 - 0.081 13.4 0.1 0.32 11.5 0.1 2.0 1 1 1 2 2 2 0 Nucleolar complex-associated protein CUT PF02376.15 KFO98009.1 - 0.092 12.9 1.1 0.28 11.4 0.1 2.3 3 0 0 3 3 2 0 CUT domain YdaS_antitoxin PF15943.5 KFO98009.1 - 0.11 12.4 1.1 0.9 9.4 0.1 2.3 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 KFO98009.1 - 0.25 11.2 0.2 0.25 11.2 0.2 2.6 3 0 0 3 3 3 0 Homeodomain-like domain CCSAP PF15748.5 KFO98011.1 - 1.4e-48 166.3 22.3 1.6e-48 166.1 22.3 1.0 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated Ras PF00071.22 KFO98012.1 - 1.7e-59 200.0 0.2 1.9e-59 199.9 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO98012.1 - 2.2e-33 115.0 0.1 3e-33 114.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO98012.1 - 2.5e-14 53.1 0.0 3.2e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFO98012.1 - 4.8e-06 26.2 0.1 0.00029 20.4 0.1 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFO98012.1 - 8.1e-05 22.7 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFO98012.1 - 0.00071 19.0 0.0 0.001 18.5 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFO98012.1 - 0.0015 18.0 0.0 0.0025 17.3 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KFO98012.1 - 0.0018 18.2 0.2 0.9 9.4 0.1 2.3 2 1 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 KFO98012.1 - 0.0045 16.5 0.0 0.0076 15.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region PduV-EutP PF10662.9 KFO98012.1 - 0.0076 16.0 0.1 0.024 14.4 0.0 1.8 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KFO98012.1 - 0.016 15.5 0.1 0.095 13.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 KFO98012.1 - 0.03 13.6 0.1 0.06 12.7 0.1 1.5 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 KFO98012.1 - 0.031 14.7 0.0 0.041 14.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 KFO98012.1 - 0.032 14.0 0.0 2.8 7.7 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.18 KFO98012.1 - 0.049 12.9 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Septin ATPase_2 PF01637.18 KFO98012.1 - 0.073 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KFO98012.1 - 0.074 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 KFO98012.1 - 0.085 12.1 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 KFO98012.1 - 0.12 12.8 0.2 0.92 9.9 0.2 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ras PF00071.22 KFO98013.1 - 5.8e-35 120.3 0.0 6.9e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO98013.1 - 2.5e-12 47.1 0.0 6.1e-12 45.8 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Lipase_GDSL_3 PF14606.6 KFO98013.1 - 0.00042 20.5 0.0 0.00055 20.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family GTP_EFTU PF00009.27 KFO98013.1 - 0.055 13.0 0.0 0.13 11.8 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Abhydrolase_2 PF02230.16 KFO98013.1 - 0.11 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase SLBP_RNA_bind PF15247.6 KFO98013.1 - 0.12 12.5 1.7 0.23 11.6 0.5 1.9 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain CAAP1 PF15335.6 KFO98013.1 - 5.6 7.6 6.1 10 6.7 0.7 3.1 3 0 0 3 3 3 0 Caspase activity and apoptosis inhibitor 1 SprT-like PF10263.9 KFO98014.1 - 9.4e-24 83.5 0.0 1.7e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 SprT-like family Aminopep PF10023.9 KFO98014.1 - 0.091 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative aminopeptidase WLM PF08325.10 KFO98014.1 - 0.29 11.2 2.4 2.1 8.4 0.1 2.4 2 0 0 2 2 2 0 WLM domain 2OG-FeII_Oxy_3 PF13640.6 KFO98015.1 - 9.9e-17 61.6 0.0 1.1e-16 61.5 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KFO98015.1 - 1.6e-09 38.3 0.0 1.6e-09 38.3 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cupin_1 PF00190.22 KFO98015.1 - 0.11 12.1 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Cupin Translin PF01997.16 KFO98016.1 - 5.3e-49 167.0 0.0 6.5e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Translin family UVR PF02151.19 KFO98017.1 - 0.0023 17.6 8.1 0.0023 17.6 8.1 3.1 2 0 0 2 2 2 1 UvrB/uvrC motif Laminin_II PF06009.12 KFO98017.1 - 3 7.9 14.0 0.77 9.8 0.3 3.9 3 1 1 4 4 4 0 Laminin Domain II Baculo_p24 PF05073.12 KFO98017.1 - 3.7 7.3 8.2 0.53 10.1 0.4 2.9 2 2 0 2 2 2 0 Baculovirus P24 capsid protein Ead_Ea22 PF13935.6 KFO98017.1 - 4.5 7.9 15.9 0.69 10.6 0.6 3.2 1 1 1 3 3 3 0 Ead/Ea22-like protein DUF3450 PF11932.8 KFO98017.1 - 5.6 6.2 20.2 0.3 10.3 7.1 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF4988 PF16378.5 KFO98017.1 - 6.9 6.3 6.5 7.1 6.3 0.2 3.3 4 0 0 4 4 4 0 Domain of unknown function Phlebovirus_NSM PF07246.11 KFO98017.1 - 7.4 5.9 11.2 4.8 6.5 3.1 3.3 3 0 0 3 3 3 0 Phlebovirus nonstructural protein NS-M Fungal_TACC PF12709.7 KFO98017.1 - 9.7 6.7 19.4 0.23 12.0 4.5 4.4 3 2 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins SPAR_C PF11881.8 KFO98018.1 - 2.4e-69 233.9 1.5 3.4e-69 233.4 0.2 2.0 2 0 0 2 2 2 1 C-terminal domain of SPAR protein Rap_GAP PF02145.15 KFO98018.1 - 4.8e-67 225.1 0.0 1e-66 224.0 0.0 1.6 1 0 0 1 1 1 1 Rap/ran-GAP PDZ_6 PF17820.1 KFO98018.1 - 1.5e-05 24.7 0.0 3.3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFO98018.1 - 2.4e-05 24.6 0.0 4.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain bZIP_2 PF07716.15 KFO98018.1 - 0.37 10.9 4.8 1.5 9.0 4.8 2.1 1 0 0 1 1 1 0 Basic region leucine zipper DivIC PF04977.15 KFO98018.1 - 5.9 6.7 5.5 13 5.6 5.5 1.5 1 0 0 1 1 1 0 Septum formation initiator AA_permease_2 PF13520.6 KFO98019.1 - 1.4e-54 185.6 42.0 1.7e-54 185.3 42.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFO98019.1 - 3.1e-22 78.8 39.9 4.1e-22 78.4 39.9 1.1 1 0 0 1 1 1 1 Amino acid permease LRR_4 PF12799.7 KFO98020.1 - 1.4e-15 57.2 20.3 2.3e-09 37.4 1.8 4.6 2 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFO98020.1 - 7.2e-12 45.1 0.8 5.4e-06 26.0 0.7 3.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KFO98020.1 - 8.5e-11 41.5 23.3 1.1e-07 31.5 8.1 3.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 KFO98020.1 - 1.3 9.2 27.1 0.68 10.1 0.2 5.3 4 1 2 6 6 6 0 Leucine Rich repeat UPF0113_N PF17833.1 KFO98020.1 - 8 7.1 10.8 0.35 11.5 0.4 3.6 3 0 0 3 3 3 0 UPF0113 Pre-PUA domain Carb_anhydrase PF00194.21 KFO98021.1 - 1.4e-87 293.4 0.0 1.6e-87 293.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 KFO98022.1 - 4.3e-74 249.3 0.0 5.4e-74 248.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 KFO98023.1 - 1.9e-78 263.5 0.0 2.2e-78 263.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 KFO98024.1 - 2.8e-94 315.4 0.0 3.1e-94 315.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase vATP-synt_AC39 PF01992.16 KFO98025.1 - 2.6e-111 372.3 0.5 3e-111 372.2 0.5 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit TLP1_add_C PF18313.1 KFO98025.1 - 0.14 12.1 0.0 1.6 8.8 0.0 2.3 2 1 0 2 2 2 0 Thiolase-like protein type 1 additional C-terminal domain HECT PF00632.25 KFO98026.1 - 1.6e-97 326.7 0.5 2.3e-97 326.2 0.5 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KFO98026.1 - 2.9e-50 168.0 31.0 2.1e-13 50.1 1.5 4.5 4 0 0 4 4 4 4 WW domain C2 PF00168.30 KFO98026.1 - 1.2e-11 44.8 0.2 3.2e-11 43.4 0.2 1.7 1 0 0 1 1 1 1 C2 domain TPR_1 PF00515.28 KFO98027.1 - 1.5e-07 30.9 11.0 0.18 11.7 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 KFO98027.1 - 3.5e-07 30.1 0.2 0.27 11.7 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFO98027.1 - 6.5e-06 26.6 0.4 0.26 11.8 0.0 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFO98027.1 - 4.5e-05 23.2 13.2 0.82 9.9 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFO98027.1 - 0.00018 22.1 0.6 3 8.9 0.4 4.5 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFO98027.1 - 0.00022 21.8 0.2 2.6 8.8 0.0 4.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFO98027.1 - 0.028 14.1 0.1 0.94 9.2 0.0 3.2 3 0 0 3 3 3 0 TPR repeat TPR_8 PF13181.6 KFO98027.1 - 0.088 13.1 6.3 2.4 8.6 0.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO98027.1 - 0.17 12.1 6.6 1.9 8.8 0.9 3.4 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Copine PF07002.16 KFO98028.1 - 2.4e-91 305.1 0.0 3.5e-91 304.5 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 KFO98028.1 - 1.5e-28 99.1 0.1 7.8e-14 51.8 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 KFO98028.1 - 1.2e-05 25.5 0.0 6e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 vWA found in TerF C terminus DUF3211 PF11485.8 KFO98028.1 - 0.062 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3211) Yos1 PF08571.10 KFO98030.1 - 2.2e-15 56.7 0.1 2.4e-15 56.6 0.1 1.0 1 0 0 1 1 1 1 Yos1-like Hydrolase_6 PF13344.6 KFO98031.1 - 1.9e-16 60.0 0.0 3.2e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFO98031.1 - 1.7e-15 56.8 0.0 3.9e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 KFO98031.1 - 0.00016 21.8 0.0 0.00095 19.3 0.0 2.2 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFO98031.1 - 0.091 13.0 0.3 0.63 10.3 0.3 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF4032 PF13224.6 KFO98031.1 - 0.094 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4032) AAA PF00004.29 KFO98032.1 - 7.8e-37 126.6 0.0 1.6e-36 125.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFO98032.1 - 1.6e-10 40.6 0.0 6e-10 38.8 0.0 1.9 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 KFO98032.1 - 5.9e-05 22.9 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFO98032.1 - 0.0002 21.8 0.0 0.00053 20.4 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KFO98032.1 - 0.00055 19.3 0.0 0.00091 18.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 KFO98032.1 - 0.00066 19.7 0.0 0.0019 18.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFO98032.1 - 0.0015 18.8 0.1 0.0047 17.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KFO98032.1 - 0.0042 16.8 0.0 0.0094 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KFO98032.1 - 0.0045 17.0 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KFO98032.1 - 0.0065 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 KFO98032.1 - 0.0069 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KFO98032.1 - 0.0074 16.7 0.0 0.02 15.3 0.0 1.8 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 KFO98032.1 - 0.009 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 KFO98032.1 - 0.028 14.6 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFO98032.1 - 0.031 14.8 0.0 0.071 13.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KFO98032.1 - 0.061 12.4 0.1 0.25 10.4 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 KFO98032.1 - 0.066 12.9 0.1 1.7 8.4 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain TsaE PF02367.17 KFO98032.1 - 0.071 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KFO98032.1 - 0.088 12.4 0.3 0.24 10.9 0.2 1.7 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.13 KFO98032.1 - 0.096 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.16 KFO98032.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 KFO98032.1 - 0.16 12.2 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain PINIT PF14324.6 KFO98033.1 - 5.9e-35 120.7 0.0 1.2e-34 119.7 0.0 1.6 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KFO98033.1 - 5.7e-22 77.2 5.2 1.2e-21 76.1 5.2 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KFO98033.1 - 0.00051 19.8 1.6 0.00051 19.8 1.6 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 KFO98033.1 - 0.22 11.5 2.2 0.46 10.4 2.2 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 KFO98034.1 - 1.3e-14 54.2 6.2 1.3e-14 54.2 6.2 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFO98034.1 - 2.9e-11 43.0 6.9 2.9e-11 43.0 6.9 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFO98034.1 - 5.4e-09 35.6 1.9 5.4e-09 35.6 1.9 2.6 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KFO98034.1 - 4.9e-08 32.7 3.8 9.5e-08 31.8 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFO98034.1 - 8.6e-08 32.4 6.3 2.4e-07 30.9 6.3 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFO98034.1 - 1.8e-07 30.9 4.8 1.8e-07 30.9 4.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFO98034.1 - 5.7e-07 29.4 8.4 8.1e-07 28.9 3.2 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFO98034.1 - 1.4e-05 25.0 2.2 3.8e-05 23.6 2.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFO98034.1 - 4.5e-05 23.2 4.1 4.5e-05 23.2 4.1 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFO98034.1 - 0.003 17.6 4.3 0.0073 16.3 4.3 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFO98034.1 - 0.03 14.0 5.1 0.068 12.8 5.1 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type OrfB_Zn_ribbon PF07282.11 KFO98034.1 - 0.043 13.7 0.9 0.84 9.6 0.1 2.3 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-Nse PF11789.8 KFO98034.1 - 0.064 13.1 1.3 0.17 11.8 1.3 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KFO98034.1 - 0.067 13.0 3.8 0.12 12.2 3.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 KFO98034.1 - 0.1 12.7 6.5 0.3 11.2 6.5 1.8 1 1 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 KFO98034.1 - 0.17 11.8 4.1 2.2 8.3 1.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 KFO98034.1 - 0.22 11.7 5.2 1 9.6 5.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KFO98034.1 - 0.54 10.6 3.7 1 9.7 3.7 1.5 1 0 0 1 1 1 0 RING-like domain zf-P11 PF03854.14 KFO98034.1 - 1.1 9.0 4.4 0.59 9.8 1.2 2.1 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_10 PF16685.5 KFO98034.1 - 3.6 7.8 8.8 0.49 10.6 4.0 1.9 2 0 0 2 2 2 0 zinc RING finger of MSL2 RNF111_N PF15303.6 KFO98035.1 - 1e-43 150.1 28.3 1.6e-43 149.5 28.3 1.3 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase Arkadia N-terminus SLM4 PF16818.5 KFO98036.1 - 0.014 15.4 1.4 0.021 14.8 1.4 1.3 1 0 0 1 1 1 0 Protein SLM4 Peptidase_M16 PF00675.20 KFO98036.1 - 1.2 9.2 4.6 1.2 9.1 1.0 2.1 1 1 0 2 2 2 0 Insulinase (Peptidase family M16) PEP-utilisers_N PF05524.13 KFO98036.1 - 4.8 7.4 7.7 1.8 8.8 3.6 2.1 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal ATP-synt_ab PF00006.25 KFO98037.1 - 1.9e-74 249.9 0.0 3e-74 249.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KFO98037.1 - 1.3e-47 161.2 2.1 2.2e-47 160.5 2.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KFO98037.1 - 1.1e-17 64.3 1.8 2.9e-17 62.9 1.8 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF4142 PF13628.6 KFO98037.1 - 2.8e-05 24.4 1.6 5e-05 23.6 1.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4142) FCH PF00611.23 KFO98038.1 - 1.3e-12 47.8 0.0 1.3e-12 47.8 0.0 2.7 1 1 1 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Atg14 PF10186.9 KFO98038.1 - 0.39 9.7 12.7 0.24 10.4 10.6 1.5 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KFO98038.1 - 0.42 9.4 19.3 0.053 12.4 9.3 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein COG2 PF06148.11 KFO98038.1 - 0.54 10.3 7.8 0.43 10.7 1.9 2.9 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Snapin_Pallidin PF14712.6 KFO98038.1 - 0.76 10.2 8.7 0.3 11.5 4.6 2.3 2 0 0 2 2 2 0 Snapin/Pallidin UCH PF00443.29 KFO98039.1 - 0.01 15.3 0.1 0.031 13.8 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase UT PF03253.14 KFO98040.1 - 1.7e-210 697.0 76.3 5.6e-106 353.9 34.4 2.0 2 0 0 2 2 2 2 Urea transporter AT_hook PF02178.19 KFO98041.1 - 5.2 7.3 39.9 0.1 12.5 1.5 5.1 4 0 0 4 4 4 0 AT hook motif Ion_trans PF00520.31 KFO98042.1 - 5.5e-33 114.2 13.9 8.4e-33 113.6 13.9 1.2 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.11 KFO98042.1 - 1.3e-28 99.0 0.8 2.8e-28 97.9 0.8 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.7 KFO98042.1 - 6.2e-10 39.5 0.6 2.2e-05 25.0 0.4 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFO98042.1 - 1.7e-09 38.0 0.0 0.00097 19.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFO98042.1 - 1.5e-06 28.1 2.6 0.13 12.9 0.1 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KFO98042.1 - 6.6e-05 23.1 0.1 1.1 9.6 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KFO98042.1 - 0.00016 22.0 0.4 1 9.9 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat PKD_channel PF08016.12 KFO98042.1 - 0.00035 19.4 15.3 0.0044 15.8 15.4 2.3 1 1 0 1 1 1 1 Polycystin cation channel Gp-FAR-1 PF05823.12 KFO98042.1 - 1.1 9.7 6.1 7.1 7.0 0.1 2.9 3 0 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Homeodomain PF00046.29 KFO98043.1 - 7.9e-22 76.9 2.6 1.4e-21 76.0 2.6 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO98043.1 - 0.018 14.9 0.0 0.06 13.3 0.0 1.9 1 0 0 1 1 1 0 Homeobox KN domain DUF874 PF05917.11 KFO98043.1 - 0.056 12.5 1.7 0.097 11.7 1.7 1.3 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) PDZ_6 PF17820.1 KFO98045.1 - 2e-11 43.5 0.1 4.3e-11 42.5 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFO98045.1 - 2.9e-08 33.9 0.1 7.2e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 PDZ domain C1_1 PF00130.22 KFO98045.1 - 1.5e-07 31.1 16.2 3.3e-07 30.1 16.2 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PDZ PF00595.24 KFO98045.1 - 2.4e-07 31.0 0.1 6.5e-07 29.6 0.1 1.7 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KFO98045.1 - 0.0036 17.6 0.0 0.0068 16.7 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain MFS_1 PF07690.16 KFO98046.1 - 9.8e-45 153.0 38.1 9.7e-38 130.0 28.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFO98046.1 - 5.5e-10 38.7 27.0 1.9e-09 36.9 2.2 2.5 1 1 1 3 3 3 2 Sugar (and other) transporter LacY_symp PF01306.19 KFO98046.1 - 0.011 14.5 18.3 0.0072 15.1 7.3 2.9 2 1 0 2 2 2 0 LacY proton/sugar symporter Sigma_reg_N PF13800.6 KFO98046.1 - 0.071 13.4 1.1 0.19 12.0 1.1 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal SAYSvFN PF10260.9 KFO98046.1 - 0.7 9.8 3.6 0.33 10.9 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) CPP1-like PF11833.8 KFO98046.1 - 1 9.0 3.0 2.8 7.5 3.0 1.8 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF2070 PF09843.9 KFO98046.1 - 8.7 4.5 13.7 0.027 12.8 0.9 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) Ion_trans_2 PF07885.16 KFO98047.1 - 1.9e-29 101.5 22.8 2.8e-18 65.6 4.2 2.9 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KFO98047.1 - 7.8e-05 22.0 16.3 0.016 14.5 5.5 2.5 2 1 0 2 2 2 2 Ion transport protein PIRT PF15099.6 KFO98047.1 - 0.044 13.4 0.0 0.22 11.1 0.0 2.2 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Homeodomain PF00046.29 KFO98048.1 - 9.9e-23 79.8 7.6 1.4e-22 79.3 7.6 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO98048.1 - 0.00073 19.4 0.7 0.0017 18.2 0.7 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 KFO98048.1 - 0.015 14.7 0.2 0.032 13.7 0.2 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_28 PF13518.6 KFO98048.1 - 0.016 15.3 0.1 0.04 14.1 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 KFO98048.1 - 0.1 12.4 0.1 0.66 9.9 0.0 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain YdaS_antitoxin PF15943.5 KFO98048.1 - 0.13 12.2 0.1 0.34 10.8 0.1 1.8 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT CENP-B_N PF04218.13 KFO98048.1 - 0.13 11.9 1.4 0.19 11.4 0.1 1.9 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain Spc7 PF08317.11 KFO98049.1 - 0.00047 19.1 16.0 0.00047 19.1 16.0 4.3 2 1 2 4 4 4 2 Spc7 kinetochore protein DUF3800 PF12686.7 KFO98049.1 - 0.39 11.4 4.2 1.1e+02 3.5 4.2 3.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Enolase_C PF00113.22 KFO98050.1 - 2.4e-25 89.4 0.1 3.2e-22 79.2 0.0 2.2 2 0 0 2 2 2 2 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KFO98050.1 - 2.3e-14 53.7 2.1 2.6e-08 34.1 0.1 2.6 3 0 0 3 3 3 2 Enolase, N-terminal domain HSP70 PF00012.20 KFO98051.1 - 1e-06 27.3 0.1 0.04 12.1 0.0 3.2 3 0 0 3 3 3 3 Hsp70 protein GA-like PF17573.2 KFO98051.1 - 0.06 13.3 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 GA-like domain FGGY_C PF02782.16 KFO98051.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain IRK_N PF08466.10 KFO98051.1 - 0.55 10.4 1.7 1.7 8.9 1.3 2.1 1 1 1 2 2 2 0 Inward rectifier potassium channel N-terminal Lipase PF00151.19 KFO98052.1 - 1.1e-67 228.7 1.4 8.4e-67 225.9 1.4 1.9 1 1 0 1 1 1 1 Lipase PLAT PF01477.23 KFO98052.1 - 1.5e-09 38.5 0.4 2.7e-09 37.6 0.4 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain Lipase PF00151.19 KFO98053.1 - 4.4e-56 190.6 0.0 5.5e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Lipase MG1 PF17790.1 KFO98053.1 - 0.11 13.0 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Macroglobulin domain MG1 Lipase PF00151.19 KFO98054.1 - 1.4e-62 211.9 0.0 1.6e-62 211.7 0.0 1.0 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 KFO98054.1 - 0.0028 18.3 0.8 0.0037 17.9 0.8 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFO98054.1 - 0.01 15.1 0.0 0.011 15.1 0.0 1.0 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Rab5-bind PF09311.11 KFO98055.1 - 0.0013 18.1 12.8 0.0013 18.1 12.8 2.3 1 1 0 2 2 2 1 Rabaptin-like protein Syntaxin-6_N PF09177.11 KFO98055.1 - 0.0022 18.5 7.1 0.0022 18.5 7.1 2.3 2 1 1 3 3 3 1 Syntaxin 6, N-terminal Spc24 PF08286.11 KFO98055.1 - 0.0066 16.7 22.0 0.058 13.6 2.7 3.2 1 1 2 3 3 3 2 Spc24 subunit of Ndc80 ATG16 PF08614.11 KFO98055.1 - 0.047 13.9 19.0 0.087 13.0 19.0 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 KFO98055.1 - 0.13 12.3 30.6 0.013 15.5 21.6 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 KFO98055.1 - 1.2 8.4 13.5 0.17 11.1 8.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ADIP PF11559.8 KFO98055.1 - 1.6 8.8 22.6 0.16 12.1 11.8 2.7 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF5082 PF16888.5 KFO98055.1 - 3 8.1 18.9 0.6 10.4 3.4 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF745 PF05335.13 KFO98055.1 - 4 7.1 10.9 1.4 8.6 4.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) PRP1_N PF06424.12 KFO98055.1 - 4 7.8 13.9 60 4.0 13.9 2.6 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal GDNF PF02351.16 KFO98056.1 - 4.1e-39 133.4 47.1 3e-21 76.2 7.0 3.1 3 0 0 3 3 3 3 GDNF/GAS1 domain Kelch_5 PF13854.6 KFO98057.1 - 8.3e-27 92.7 18.4 4.6e-08 32.9 0.0 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KFO98057.1 - 7e-20 70.8 6.1 4e-05 23.5 0.1 6.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 KFO98057.1 - 3.7e-19 68.0 15.4 8.9e-05 22.0 0.2 6.7 7 0 0 7 7 7 5 Kelch motif Kelch_6 PF13964.6 KFO98057.1 - 3.7e-18 65.1 13.3 1.7e-05 24.9 0.0 6.4 6 0 0 6 6 6 5 Kelch motif PSI PF01437.25 KFO98057.1 - 5.1e-18 65.3 54.0 1.4e-12 48.0 9.6 8.3 7 1 0 7 7 6 5 Plexin repeat Lectin_C PF00059.21 KFO98057.1 - 8.1e-16 58.7 0.1 8.1e-16 58.7 0.1 3.5 4 1 0 4 4 1 1 Lectin C-type domain Kelch_3 PF13415.6 KFO98057.1 - 1.2e-12 47.7 9.5 0.00051 20.3 0.0 6.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KFO98057.1 - 5.9e-12 45.1 7.7 0.018 15.0 0.1 5.5 5 0 0 5 5 5 3 Kelch motif CUB PF00431.20 KFO98057.1 - 2.3e-11 44.0 0.0 6.9e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 CUB domain EGF_2 PF07974.13 KFO98057.1 - 8.9e-05 22.8 10.2 8.9e-05 22.8 10.2 8.7 5 2 0 5 5 2 2 EGF-like domain Laminin_EGF PF00053.24 KFO98057.1 - 0.00011 22.3 18.3 0.00011 22.3 18.3 8.5 5 3 2 7 7 4 2 Laminin EGF domain PSI_integrin PF17205.3 KFO98057.1 - 0.0013 18.4 7.7 0.0013 18.4 7.7 6.7 7 0 0 7 7 4 2 Integrin plexin domain TruB_N PF01509.18 KFO98058.1 - 7.9e-50 169.1 0.0 1e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) RAI16-like PF10257.9 KFO98059.1 - 2.2e-138 461.0 3.5 2.8e-138 460.7 3.5 1.1 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein AbLIM_anchor PF16182.5 KFO98060.1 - 3.1e-118 395.9 17.9 6.6e-89 299.4 15.7 2.1 1 1 1 2 2 2 2 Putative adherens-junction anchoring region of AbLIM LIM PF00412.22 KFO98060.1 - 2.1e-44 149.5 42.1 6.9e-15 55.0 1.7 5.0 4 1 1 5 5 5 4 LIM domain VHP PF02209.19 KFO98060.1 - 1.4e-15 57.1 1.2 2.2e-15 56.4 0.6 1.7 2 0 0 2 2 2 1 Villin headpiece domain VWA PF00092.28 KFO98061.1 - 1.8e-93 311.6 0.0 7.1e-36 124.1 0.0 3.0 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 KFO98061.1 - 2e-37 128.1 0.0 9.6e-15 55.2 0.0 3.5 3 0 0 3 3 3 3 von Willebrand factor type A domain EGF PF00008.27 KFO98061.1 - 1.5e-14 53.9 25.2 1.3e-08 35.0 9.5 2.7 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 KFO98061.1 - 4.8e-07 30.2 18.6 0.00037 21.0 5.6 2.9 2 0 0 2 2 2 2 Human growth factor-like EGF VWA_3 PF13768.6 KFO98061.1 - 1e-06 28.7 0.0 0.099 12.6 0.0 3.3 3 0 0 3 3 3 2 von Willebrand factor type A domain EGF_2 PF07974.13 KFO98061.1 - 0.11 12.9 29.3 1.1 9.7 9.7 2.7 2 0 0 2 2 2 0 EGF-like domain FXa_inhibition PF14670.6 KFO98061.1 - 1.1 9.6 19.1 5.6 7.3 5.5 2.8 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFO98061.1 - 5.1 7.1 7.5 14 5.7 0.6 2.7 2 0 0 2 2 2 0 Complement Clr-like EGF-like Filament PF00038.21 KFO98062.1 - 0.0059 16.2 18.9 0.0059 16.2 18.9 5.7 2 1 3 5 5 5 2 Intermediate filament protein HTH_25 PF13413.6 KFO98062.1 - 2.6 8.0 6.1 1.9 8.4 0.1 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain NHL PF01436.21 KFO98063.1 - 7e-31 104.7 3.6 9.1e-07 28.6 0.0 8.0 10 0 0 10 10 10 4 NHL repeat Thioredoxin_8 PF13905.6 KFO98063.1 - 3.7e-13 49.6 0.0 1.1e-12 48.1 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like Arylesterase PF01731.20 KFO98063.1 - 6.2e-07 29.5 0.0 0.1 12.8 0.0 4.1 4 0 0 4 4 4 2 Arylesterase SGL PF08450.12 KFO98063.1 - 1.2e-06 28.3 0.1 0.00019 21.1 0.0 3.8 3 2 1 4 4 4 1 SMP-30/Gluconolactonase/LRE-like region Thioredoxin PF00085.20 KFO98063.1 - 0.0036 17.3 0.0 0.19 11.7 0.1 2.4 1 1 1 2 2 2 1 Thioredoxin DRMBL PF07522.14 KFO98064.1 - 2e-28 98.8 1.2 4.8e-28 97.5 0.0 2.3 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KFO98064.1 - 0.0013 18.3 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KFO98064.1 - 0.054 13.5 0.2 0.12 12.4 0.2 1.6 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily RMMBL PF07521.12 KFO98064.1 - 0.058 13.3 0.0 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain PH PF00169.29 KFO98065.1 - 1.9e-10 41.2 0.2 4.1e-10 40.1 0.2 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFO98065.1 - 0.0012 19.0 0.2 0.095 13.0 0.2 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFO98065.1 - 0.0023 18.3 0.5 0.0086 16.5 0.5 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain Trypsin PF00089.26 KFO98066.1 - 6.4e-68 228.9 0.1 8.4e-68 228.5 0.1 1.2 1 0 0 1 1 1 1 Trypsin Kringle PF00051.18 KFO98066.1 - 6.8e-20 71.2 4.7 2.6e-19 69.3 4.7 2.1 1 0 0 1 1 1 1 Kringle domain EGF PF00008.27 KFO98066.1 - 7.5e-14 51.7 43.7 9e-08 32.3 6.9 4.7 4 0 0 4 4 4 2 EGF-like domain Trypsin_2 PF13365.6 KFO98066.1 - 9.1e-06 26.6 0.0 2.1e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain hEGF PF12661.7 KFO98066.1 - 0.0035 17.9 4.5 0.0035 17.9 4.5 5.7 6 0 0 6 6 6 2 Human growth factor-like EGF EGF_2 PF07974.13 KFO98066.1 - 0.0062 16.9 9.9 0.0062 16.9 9.9 4.7 4 0 0 4 4 4 2 EGF-like domain DUF316 PF03761.15 KFO98066.1 - 0.0099 15.5 0.0 0.13 11.8 0.0 2.1 2 0 0 2 2 2 1 Chymotrypsin family Peptidase-S1 DUF1986 PF09342.11 KFO98066.1 - 0.068 13.6 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) RVT_1 PF00078.27 KFO98067.1 - 0.00046 19.8 0.0 0.00066 19.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CTNNB1_binding PF08347.11 KFO98068.1 - 7.5e-38 130.8 7.8 7.5e-38 130.8 7.8 2.9 2 1 0 2 2 2 1 N-terminal CTNNB1 binding HMG_box PF00505.19 KFO98068.1 - 2.4e-22 79.1 1.0 4.8e-22 78.1 1.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFO98068.1 - 2.3e-08 34.5 2.0 4.8e-08 33.5 2.0 1.5 1 0 0 1 1 1 1 HMG-box domain V-SNARE_C PF12352.8 KFO98069.1 - 3e-22 78.7 6.0 1e-20 73.8 5.7 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 KFO98069.1 - 2.9e-18 66.0 4.7 2.9e-18 66.0 4.7 2.6 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Laminin_II PF06009.12 KFO98069.1 - 0.0032 17.5 0.8 0.31 11.0 0.0 2.2 2 0 0 2 2 2 1 Laminin Domain II Mer2 PF09074.10 KFO98069.1 - 0.025 14.4 3.6 0.87 9.4 0.2 2.2 1 1 1 2 2 2 0 Mer2 Peptidase_S46 PF10459.9 KFO98069.1 - 0.035 12.8 6.3 0.039 12.6 6.3 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF5344 PF17279.2 KFO98069.1 - 0.049 14.2 1.0 2 9.1 0.1 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5344) SKA2 PF16740.5 KFO98069.1 - 0.049 13.4 0.6 0.049 13.4 0.6 2.6 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF1664 PF07889.12 KFO98069.1 - 0.063 13.3 3.2 0.94 9.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DegQ PF08181.11 KFO98069.1 - 0.11 12.6 1.9 0.45 10.7 1.7 2.0 2 0 0 2 2 2 0 DegQ (SacQ) family Sec8_exocyst PF04048.14 KFO98069.1 - 0.19 11.6 2.0 3.2 7.6 0.1 2.4 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain Sec20 PF03908.13 KFO98069.1 - 0.31 11.0 1.8 1.6 8.7 0.2 2.4 2 1 0 2 2 2 0 Sec20 DUF4407 PF14362.6 KFO98069.1 - 0.4 10.0 6.6 0.46 9.8 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MetOD2 PF18548.1 KFO98069.1 - 0.59 10.3 8.6 4 7.6 1.4 2.3 2 0 0 2 2 2 0 Metanogen output domain 2 DUF745 PF05335.13 KFO98069.1 - 0.62 9.8 7.8 6.5 6.4 3.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF745) Exonuc_VII_L PF02601.15 KFO98069.1 - 0.67 9.5 10.5 2 7.9 10.5 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit Metal_resist PF13801.6 KFO98069.1 - 0.76 10.0 8.1 8.2 6.6 0.4 2.7 2 2 0 2 2 2 0 Heavy-metal resistance Spc7 PF08317.11 KFO98069.1 - 2.8 6.7 12.6 2.9 6.7 3.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2203 PF09969.9 KFO98069.1 - 6.3 7.6 7.3 3.1e+02 2.1 7.3 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DHHC PF01529.20 KFO98070.1 - 5.8e-36 123.6 9.0 8.7e-36 123.0 9.0 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase SH3_2 PF07653.17 KFO98070.1 - 1e-07 31.5 0.3 4e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain AMP-binding PF00501.28 KFO98071.1 - 2e-113 379.2 0.0 2.7e-113 378.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFO98071.1 - 1.7e-05 25.7 0.1 5.6e-05 24.0 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Zona_pellucida PF00100.23 KFO98072.1 - 4e-34 118.6 7.3 4.6e-34 118.4 7.3 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Myelin_MBP PF01669.17 KFO98072.1 - 0.17 12.5 0.0 0.26 11.9 0.0 1.3 1 0 0 1 1 1 0 Myelin basic protein Acyltransferase PF01553.21 KFO98073.1 - 5.9e-23 81.0 0.0 1.4e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase 7tm_1 PF00001.21 KFO98074.1 - 3.2e-78 262.7 0.1 4.3e-78 262.3 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFO98074.1 - 9.9e-11 41.5 13.3 2e-06 27.4 5.5 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFO98074.1 - 4.8e-07 29.8 8.4 1.3e-05 25.1 5.4 2.3 2 0 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFO98074.1 - 1.7e-05 24.6 13.1 1.7e-05 24.6 13.1 2.3 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx T2SSM PF04612.12 KFO98074.1 - 0.2 11.7 0.1 0.4 10.7 0.1 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M LRR_8 PF13855.6 KFO98075.1 - 1.7e-56 187.8 67.0 1.3e-11 44.0 7.1 8.9 4 3 6 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 KFO98075.1 - 6.8e-39 131.2 72.7 1.6e-06 28.3 3.6 10.8 5 3 6 12 12 12 12 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFO98075.1 - 3.2e-12 46.3 36.0 0.0045 16.5 2.2 5.8 2 2 4 6 6 6 5 Leucine-rich repeat LRR_5 PF13306.6 KFO98075.1 - 2.3e-06 27.6 3.1 0.13 12.3 0.9 4.3 1 1 4 5 5 5 4 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFO98075.1 - 1.6e-05 24.8 60.9 4.2 8.3 0.7 17.0 18 2 0 18 18 18 2 Leucine Rich Repeat HERV-K_REC PF15695.5 KFO98075.1 - 0.071 13.2 1.5 2.7 8.1 0.1 3.6 3 0 0 3 3 3 0 Rec (regulator of expression encoded by corf) of HERV-K-113 SUFU_C PF12470.8 KFO98075.1 - 0.64 10.0 2.7 0.87 9.6 0.6 2.2 2 0 0 2 2 2 0 Suppressor of Fused Gli/Ci N terminal binding domain MA3 PF02847.17 KFO98076.1 - 8.6e-49 164.2 0.4 9e-26 90.1 0.3 2.1 2 0 0 2 2 2 2 MA3 domain HABP4_PAI-RBP1 PF04774.15 KFO98076.1 - 0.096 13.5 0.0 0.096 13.5 0.0 2.1 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family HAP1_N PF04849.13 KFO98077.1 - 0.0086 15.3 2.0 0.013 14.7 2.0 1.4 1 1 0 1 1 1 1 HAP1 N-terminal conserved region zf-U1 PF06220.12 KFO98077.1 - 0.012 15.4 2.6 0.02 14.7 2.6 1.3 1 0 0 1 1 1 0 U1 zinc finger NACHT_N PF17100.5 KFO98077.1 - 0.1 12.5 0.1 0.36 10.6 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase zf-C2H2_jaz PF12171.8 KFO98077.1 - 0.13 12.6 2.9 0.3 11.4 2.9 1.7 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_jaz PF12171.8 KFO98078.1 - 0.002 18.4 0.2 0.0042 17.3 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFO98078.1 - 0.054 13.9 0.3 0.13 12.7 0.3 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type RRM_1 PF00076.22 KFO98078.1 - 0.07 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SMC_N PF02463.19 KFO98079.1 - 7.2e-66 221.8 15.7 1.4e-65 220.8 15.7 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KFO98079.1 - 3.8e-21 75.6 0.0 1.1e-20 74.1 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 KFO98079.1 - 1.7e-12 47.8 12.6 1.7e-12 47.8 12.6 5.5 2 2 2 4 4 4 1 AAA ATPase domain AAA_21 PF13304.6 KFO98079.1 - 2.2e-11 44.1 20.2 3.4e-06 27.1 0.0 5.5 4 2 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFO98079.1 - 1.1e-08 35.9 47.1 1.1e-08 35.9 47.1 8.1 2 2 3 5 5 5 1 AAA domain AAA_29 PF13555.6 KFO98079.1 - 0.0041 16.8 0.0 0.0092 15.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Muted PF14942.6 KFO98079.1 - 0.0064 16.8 11.7 0.0064 16.8 11.7 8.3 2 2 7 9 9 9 1 Organelle biogenesis, Muted-like protein DSPc PF00782.20 KFO98080.1 - 7.5e-45 152.0 0.0 1.3e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 KFO98080.1 - 2.2e-06 28.1 0.0 1e-05 26.0 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.27 KFO98080.1 - 2.7e-05 23.8 0.0 4.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KFO98080.1 - 0.031 14.6 0.0 0.063 13.6 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain CDKN3 PF05706.12 KFO98080.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) SMN PF06003.12 KFO98081.1 - 1.5e-17 63.7 4.2 3.3e-17 62.6 4.2 1.7 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 KFO98081.1 - 7.9e-05 22.7 0.1 0.00034 20.6 0.0 2.2 2 1 0 2 2 2 1 Tudor domain HLH PF00010.26 KFO98082.1 - 7.9e-14 51.4 1.8 6.2e-12 45.3 1.8 2.5 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain KASH_CCD PF14662.6 KFO98082.1 - 0.00029 20.7 2.3 0.00029 20.7 2.3 1.4 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH APG6_N PF17675.1 KFO98082.1 - 0.12 12.9 8.0 0.28 11.7 8.2 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 KFO98082.1 - 0.87 10.2 6.0 0.44 11.2 3.7 1.7 2 0 0 2 2 2 0 SlyX EMP24_GP25L PF01105.24 KFO98082.1 - 3.3 7.6 5.6 0.52 10.2 1.2 1.7 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DivIC PF04977.15 KFO98082.1 - 5.1 6.9 7.6 0.84 9.5 3.5 1.7 2 0 0 2 2 2 0 Septum formation initiator Aldolase_II PF00596.21 KFO98083.1 - 5.6e-38 130.7 0.0 9.2e-38 130.0 0.0 1.4 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SWIRM-assoc_1 PF16495.5 KFO98083.1 - 0.064 13.2 3.0 7.4 6.6 0.0 2.8 2 0 0 2 2 2 0 SWIRM-associated region 1 Creatinase_N_2 PF16189.5 KFO98084.1 - 5.9e-46 156.5 0.0 9.4e-46 155.8 0.0 1.3 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KFO98084.1 - 1.5e-45 155.4 0.0 2.2e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KFO98084.1 - 1.9e-24 85.5 0.5 7.9e-24 83.5 0.1 2.3 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KFO98084.1 - 2.9e-15 57.1 0.0 2.6e-12 47.5 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain RVT_1 PF00078.27 KFO98085.1 - 3.9e-08 33.1 0.0 8.3e-08 32.0 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) FKS1_dom1 PF14288.6 KFO98085.1 - 0.16 12.3 0.0 2.6 8.4 0.0 2.1 2 0 0 2 2 2 0 1,3-beta-glucan synthase subunit FKS1, domain-1 Sortilin-Vps10 PF15902.5 KFO98086.1 - 6.4e-103 344.9 0.0 8.3e-103 344.5 0.0 1.1 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KFO98086.1 - 1.1e-36 126.7 7.4 1.8e-36 126.0 7.4 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal PKD PF00801.20 KFO98086.1 - 1.4e-12 47.3 4.1 1.3e-08 34.6 0.0 2.4 2 0 0 2 2 2 2 PKD domain BNR PF02012.20 KFO98086.1 - 0.022 14.7 13.0 7 7.1 1.0 5.9 5 0 0 5 5 5 0 BNR/Asp-box repeat TNFR_16_TM PF18422.1 KFO98086.1 - 0.45 10.5 1.8 1.2 9.2 1.8 1.7 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain RVT_1 PF00078.27 KFO98087.1 - 0.07 12.6 0.0 0.18 11.3 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) ASC PF00858.24 KFO98089.1 - 2.5e-73 247.6 0.3 2.8e-73 247.4 0.3 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel RVT_1 PF00078.27 KFO98090.1 - 0.17 11.4 0.0 0.65 9.5 0.0 2.0 3 0 0 3 3 3 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFO98091.1 - 0.044 13.3 0.0 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFO98092.1 - 0.052 13.0 0.0 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) ASC PF00858.24 KFO98093.1 - 1.3e-19 70.5 0.0 1.5e-19 70.3 0.0 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel TNFR_c6 PF00020.18 KFO98094.1 - 1.6e-25 89.2 50.3 8.1e-11 42.1 6.5 4.4 3 1 0 4 4 4 4 TNFR/NGFR cysteine-rich region DUF3762 PF12591.8 KFO98094.1 - 0.035 14.4 0.1 0.074 13.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) Ribonuc_P_40 PF08584.11 KFO98094.1 - 0.15 11.3 0.1 0.16 11.3 0.1 1.1 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit Neurexophilin PF06312.12 KFO98095.1 - 3.1e-103 343.7 2.9 3.5e-103 343.6 2.9 1.0 1 0 0 1 1 1 1 Neurexophilin Filamin PF00630.19 KFO98095.1 - 0.0097 16.7 0.6 0.86 10.5 0.0 2.2 1 1 0 2 2 2 2 Filamin/ABP280 repeat fn3 PF00041.21 KFO98096.1 - 4e-29 100.8 15.7 3e-10 40.3 0.0 5.0 5 0 0 5 5 5 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFO98096.1 - 1e-06 29.2 27.1 0.0022 18.5 0.1 5.7 6 0 0 6 6 6 3 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFO98096.1 - 4.4e-06 27.0 0.0 0.4 11.0 0.2 3.8 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III PhoD_N PF16655.5 KFO98096.1 - 0.021 15.4 0.1 1.1 9.8 0.0 3.6 3 0 0 3 3 3 0 PhoD-like phosphatase, N-terminal domain DUF2369 PF10179.9 KFO98096.1 - 0.027 14.8 0.0 2.6 8.5 0.0 3.6 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2369) Sod_Fe_C PF02777.18 KFO98097.1 - 1e-38 131.6 0.0 1.9e-38 130.7 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KFO98097.1 - 1.1e-32 112.3 3.2 1.8e-32 111.7 3.2 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Wtap PF17098.5 KFO98098.1 - 1.1e-61 207.3 13.7 1.1e-61 207.3 13.7 2.3 2 1 0 2 2 2 1 WTAP/Mum2p family Atg14 PF10186.9 KFO98098.1 - 0.012 14.8 20.0 0.041 13.0 4.3 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 KFO98098.1 - 0.24 11.5 31.9 0.69 10.0 6.4 3.6 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Lipoprotein_7 PF01540.16 KFO98098.1 - 1.7 7.8 8.1 6.9 5.8 8.1 1.9 1 1 0 1 1 1 0 Adhesin lipoprotein DUF1515 PF07439.11 KFO98098.1 - 2.8 8.0 5.2 0.8 9.8 0.3 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) SPACA9 PF15120.6 KFO98098.1 - 4 7.2 17.0 0.033 14.0 5.5 2.3 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 Tropomyosin_1 PF12718.7 KFO98098.1 - 4.3 7.5 25.6 0.2 11.8 5.0 2.9 2 1 0 2 2 2 0 Tropomyosin like Spc7 PF08317.11 KFO98098.1 - 6.5 5.5 32.2 15 4.3 14.5 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2120 PF09893.9 KFO98098.1 - 7.2 6.7 8.0 1.6 8.9 0.1 2.9 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) DUF1043 PF06295.12 KFO98098.1 - 10 6.2 27.0 0.023 14.7 7.0 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1043) Thiolase_N PF00108.23 KFO98099.1 - 2.2e-77 260.0 1.5 3e-77 259.5 1.5 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFO98099.1 - 1.4e-51 173.3 1.0 2.6e-51 172.4 1.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFO98099.1 - 0.00013 21.7 4.0 0.0003 20.5 1.2 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Dodecin PF07311.12 KFO98099.1 - 0.00079 19.6 0.1 0.0018 18.4 0.1 1.6 1 0 0 1 1 1 1 Dodecin ACP_syn_III_C PF08541.10 KFO98099.1 - 0.03 14.5 0.3 0.1 12.7 0.3 2.0 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 KFO98099.1 - 0.34 10.8 3.5 9.6 6.1 0.2 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Cpn60_TCP1 PF00118.24 KFO98100.1 - 3.7e-155 517.3 14.3 4.2e-155 517.1 14.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CAF1 PF04857.20 KFO98101.1 - 1.7e-68 231.2 0.1 2.1e-68 230.8 0.1 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease 7tm_1 PF00001.21 KFO98102.1 - 4.6e-18 65.5 27.3 9.5e-18 64.5 27.3 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFO98102.1 - 5.6e-09 36.0 20.9 5.6e-09 36.0 20.9 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.15 KFO98102.1 - 0.0043 17.0 12.3 0.0043 17.0 12.3 2.7 2 1 0 3 3 3 1 Caenorhabditis serpentine receptor-like protein, class xa PEN-2 PF10251.9 KFO98102.1 - 6 7.4 9.1 2.5 8.6 0.1 3.6 2 1 1 3 3 3 0 Presenilin enhancer-2 subunit of gamma secretase DUF1772 PF08592.11 KFO98102.1 - 8.9 6.6 7.5 83 3.5 7.2 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) CIMR PF00878.18 KFO98103.1 - 0 1226.4 87.4 3.8e-52 176.2 2.6 16.1 16 0 0 16 16 16 16 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 KFO98103.1 - 2.8e-66 224.1 89.3 1.2e-09 38.4 1.1 16.5 2 1 12 15 15 15 13 Autophagy-related protein 27 Man-6-P_recep PF02157.15 KFO98103.1 - 5e-49 166.7 34.0 7.3e-10 38.4 1.0 14.0 7 3 7 15 15 15 10 Mannose-6-phosphate receptor fn2 PF00040.19 KFO98103.1 - 3.6e-18 65.6 6.0 1.8e-17 63.3 6.0 2.4 1 0 0 1 1 1 1 Fibronectin type II domain PRKCSH_1 PF13015.6 KFO98103.1 - 2.3e-09 37.1 41.4 0.045 13.5 0.1 10.2 10 2 2 12 12 12 6 Glucosidase II beta subunit-like protein DUF4448 PF14610.6 KFO98103.1 - 0.0031 17.3 3.9 4.2 7.1 1.3 3.9 2 1 0 2 2 2 2 Protein of unknown function (DUF4448) MFS_1 PF07690.16 KFO98104.1 - 2.1e-26 92.7 40.0 6.3e-26 91.1 23.4 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFO98104.1 - 3.5e-24 85.5 17.3 3.5e-24 85.5 17.3 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Kringle PF00051.18 KFO98105.1 - 1.2e-146 477.3 70.1 5.5e-31 106.7 8.0 5.3 5 0 0 5 5 5 5 Kringle domain Trypsin PF00089.26 KFO98105.1 - 4.7e-48 163.9 0.1 1.2e-47 162.6 0.0 1.7 1 1 1 2 2 2 1 Trypsin DUF1986 PF09342.11 KFO98105.1 - 1.1e-10 41.9 0.1 2e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Helicase_C PF00271.31 KFO98106.1 - 2.4e-18 66.5 0.1 3.3e-16 59.6 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFO98106.1 - 1.3e-17 64.1 0.0 2.8e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KFO98106.1 - 1.2e-12 48.4 5.4 1.2e-12 48.4 5.4 2.0 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 KFO98106.1 - 0.00011 22.3 0.0 0.00023 21.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit KOW PF00467.29 KFO98106.1 - 0.041 13.8 0.2 0.087 12.8 0.2 1.5 1 0 0 1 1 1 0 KOW motif Spc24 PF08286.11 KFO98106.1 - 0.054 13.7 0.5 0.16 12.2 0.5 1.8 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DP PF08781.10 KFO98106.1 - 0.53 10.2 4.3 0.37 10.7 1.1 2.1 2 0 0 2 2 2 0 Transcription factor DP Osmo_CC PF08946.10 KFO98106.1 - 1.4 9.2 3.9 3.8 7.8 3.9 1.7 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Got1 PF04178.12 KFO98107.1 - 1.6e-17 64.0 15.9 1.9e-17 63.7 15.9 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3185 PF11381.8 KFO98107.1 - 2.9 8.0 15.3 0.29 11.2 0.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) Aminotran_4 PF01063.19 KFO98108.1 - 3.3e-34 118.7 0.0 3.9e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV HMG_box PF00505.19 KFO98109.1 - 2.6e-22 79.0 3.8 2.6e-22 79.0 3.8 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFO98109.1 - 5.9e-09 36.4 1.1 5.9e-09 36.4 1.1 3.4 4 0 0 4 4 4 1 HMG-box domain MPS2 PF17060.5 KFO98109.1 - 0.022 14.0 6.0 0.042 13.1 6.0 1.4 1 0 0 1 1 1 0 Monopolar spindle protein 2 Choline_kinase PF01633.20 KFO98110.1 - 1.2e-62 211.3 0.1 1.8e-62 210.7 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KFO98110.1 - 1e-13 51.8 0.0 1.6e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFO98110.1 - 2.3e-05 23.8 0.5 0.00015 21.2 0.1 2.1 2 0 0 2 2 2 1 Ecdysteroid kinase C2 PF00168.30 KFO98111.1 - 3.7e-15 56.1 0.0 7.2e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain YbjQ_1 PF01906.17 KFO98111.1 - 6.1e-05 23.6 3.4 0.026 15.1 0.0 4.7 4 1 0 4 4 4 1 Putative heavy-metal-binding Glyco_transf_29 PF00777.18 KFO98112.1 - 2.5e-78 263.2 0.0 3e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Sulfotransfer_1 PF00685.27 KFO98113.1 - 1.1e-66 225.0 6.2 3.8e-64 216.7 6.2 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFO98113.1 - 0.0013 19.1 0.1 0.013 15.8 0.0 2.1 2 0 0 2 2 2 1 Sulfotransferase family DUF2167 PF09935.9 KFO98113.1 - 0.04 13.1 0.3 0.063 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) zf-C2H2_3 PF13878.6 KFO98113.1 - 0.12 12.3 0.0 0.36 10.7 0.0 1.8 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO CTP_transf_3 PF02348.19 KFO98114.1 - 7.9e-54 182.9 0.0 1.2e-53 182.3 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 KFO98114.1 - 3.4e-06 27.5 0.0 4.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hydrolase_3 PF08282.12 KFO98114.1 - 4e-06 26.8 0.2 0.00014 21.7 0.0 2.8 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFO98114.1 - 0.052 13.6 0.0 0.22 11.6 0.0 2.1 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase ABC_membrane PF00664.23 KFO98115.1 - 9.2e-66 222.3 24.7 4.5e-33 115.1 3.5 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFO98115.1 - 3.5e-52 176.6 0.0 1.3e-24 87.3 0.0 3.4 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 KFO98115.1 - 4.1e-07 29.6 6.7 0.018 14.5 0.1 4.3 3 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFO98115.1 - 8.4e-06 25.8 2.3 0.95 9.2 0.0 3.8 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFO98115.1 - 2.4e-05 24.3 0.1 0.022 14.6 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KFO98115.1 - 0.00015 21.4 1.5 0.078 12.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KFO98115.1 - 0.0013 18.8 0.1 1.6 8.9 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase IstB_IS21 PF01695.17 KFO98115.1 - 0.0032 17.2 1.1 5.3 6.7 0.0 3.6 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_22 PF13401.6 KFO98115.1 - 0.0038 17.5 0.1 2.1 8.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 KFO98115.1 - 0.012 14.9 0.0 0.2 10.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 KFO98115.1 - 0.013 15.1 0.0 3.4 7.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 KFO98115.1 - 0.021 15.2 0.1 0.62 10.4 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 KFO98115.1 - 0.031 13.9 0.0 0.93 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KFO98115.1 - 0.035 13.3 0.0 3.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KFO98115.1 - 0.066 12.9 0.1 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 KFO98115.1 - 0.069 11.9 1.0 8.1 5.1 0.0 3.2 3 1 0 3 3 3 0 Predicted ATPase of the ABC class Sigma54_activat PF00158.26 KFO98115.1 - 0.071 12.8 0.0 2.6 7.7 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 KFO98115.1 - 0.3 10.4 1.2 9.9 5.4 0.1 2.3 2 0 0 2 2 2 0 KaiC Dynamin_N PF00350.23 KFO98115.1 - 0.44 10.6 2.7 1.8 8.6 0.1 2.9 2 0 0 2 2 2 0 Dynamin family AAA_23 PF13476.6 KFO98115.1 - 0.57 10.7 13.2 15 6.0 0.0 3.4 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KFO98115.1 - 3.7 7.2 5.8 3.5 7.2 0.1 2.8 3 0 0 3 3 3 0 AAA ATPase domain IRK_C PF17655.1 KFO98116.1 - 9.9e-72 240.2 0.0 1.4e-71 239.7 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFO98116.1 - 6.8e-59 197.7 4.8 9.9e-59 197.2 4.8 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain EI24 PF07264.11 KFO98116.1 - 0.11 12.7 3.5 0.18 12.0 3.5 1.3 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DOR PF14839.6 KFO98116.1 - 0.12 12.3 1.2 0.19 11.7 1.2 1.2 1 0 0 1 1 1 0 DOR family Ldh_1_N PF00056.23 KFO98117.1 - 2e-49 167.3 0.8 2.9e-49 166.8 0.8 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KFO98117.1 - 4.4e-23 82.1 0.0 6.6e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 KFO98117.1 - 0.00043 19.9 0.5 0.00094 18.8 0.1 1.7 1 1 1 2 2 2 1 Family 4 glycosyl hydrolase AlaDh_PNT_C PF01262.21 KFO98117.1 - 0.053 12.8 0.9 0.087 12.1 0.9 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glycogen_syn PF05693.13 KFO98118.1 - 0 1177.7 0.0 0 1177.4 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_4 PF13439.6 KFO98118.1 - 3.1e-05 24.0 0.0 7.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KFO98118.1 - 3.5e-05 23.4 0.0 0.00035 20.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFO98118.1 - 3.5e-05 24.2 0.0 0.0058 17.1 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 MRVI1 PF05781.12 KFO98120.1 - 2.6e-143 478.6 8.0 2.9e-143 478.4 8.0 1.0 1 0 0 1 1 1 1 MRVI1 protein DUF919 PF06034.11 KFO98120.1 - 0.45 10.4 4.3 0.45 10.4 2.3 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) BRE1 PF08647.11 KFO98120.1 - 0.52 10.4 8.9 0.48 10.5 7.0 1.9 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase Fib_alpha PF08702.10 KFO98120.1 - 0.73 10.0 6.6 1.3 9.2 6.6 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Syntaxin_2 PF14523.6 KFO98120.1 - 2 8.8 5.8 7.7 6.9 5.1 2.2 1 1 1 2 2 2 0 Syntaxin-like protein ISG65-75 PF11727.8 KFO98120.1 - 2.5 7.2 13.7 0.78 8.9 5.4 2.2 2 0 0 2 2 2 0 Invariant surface glycoprotein Casc1_N PF15927.5 KFO98121.1 - 1.7e-52 178.1 6.8 1.7e-52 178.1 6.8 2.0 2 0 0 2 2 2 1 Cancer susceptibility candidate 1 N-terminus Glyco_hydro_20 PF00728.22 KFO98121.1 - 0.0024 17.3 1.2 0.012 15.1 1.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain Complex1_LYR PF05347.15 KFO98122.1 - 2.9e-14 52.9 0.1 4.4e-14 52.3 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFO98122.1 - 1.2e-07 32.3 0.4 1.6e-07 31.9 0.4 1.3 1 1 0 1 1 1 1 Complex1_LYR-like SAS4 PF15460.6 KFO98122.1 - 0.071 13.2 0.0 0.075 13.1 0.0 1.2 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 Ras PF00071.22 KFO98123.1 - 1.3e-58 197.2 0.0 1.5e-58 196.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO98123.1 - 6.5e-22 78.0 0.0 1.3e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO98123.1 - 9.5e-10 38.2 0.0 1.2e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFO98123.1 - 2.4e-07 30.5 0.5 2.3e-06 27.3 0.1 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFO98123.1 - 2.5e-06 27.5 0.0 0.017 15.1 0.0 2.5 2 1 1 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 KFO98123.1 - 1.2e-05 25.4 0.1 3e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase MeaB PF03308.16 KFO98123.1 - 0.0015 17.6 0.2 0.022 13.7 0.1 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB G-alpha PF00503.20 KFO98123.1 - 0.0023 17.2 0.3 0.091 11.9 0.3 2.1 1 1 1 2 2 2 2 G-protein alpha subunit FeoB_N PF02421.18 KFO98123.1 - 0.0024 17.4 0.0 0.022 14.3 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 KFO98123.1 - 0.019 14.8 0.7 0.4 10.4 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.18 KFO98123.1 - 0.024 13.9 0.3 0.054 12.8 0.0 1.9 2 1 0 2 2 2 0 Septin AAA_25 PF13481.6 KFO98123.1 - 0.15 11.6 0.0 0.38 10.3 0.0 1.7 2 1 1 3 3 3 0 AAA domain RA PF00788.23 KFO98124.1 - 0.00025 21.6 0.3 0.0046 17.6 0.3 2.6 1 1 0 1 1 1 1 Ras association (RalGDS/AF-6) domain DUF5344 PF17279.2 KFO98124.1 - 0.023 15.2 6.1 0.023 15.2 6.1 3.4 1 1 3 4 4 4 0 Family of unknown function (DUF5344) Tropomyosin PF00261.20 KFO98124.1 - 0.048 13.0 41.4 0.062 12.7 26.9 2.2 1 1 1 2 2 2 0 Tropomyosin Fib_alpha PF08702.10 KFO98124.1 - 0.099 12.8 32.1 0.41 10.8 4.8 4.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family YscO PF07321.12 KFO98124.1 - 5.2 7.0 41.2 3.8 7.4 5.8 2.5 1 1 2 3 3 3 0 Type III secretion protein YscO HrpB7 PF09486.10 KFO98124.1 - 5.7 7.3 21.4 1.7e+02 2.5 0.6 3.8 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) HLH PF00010.26 KFO98125.1 - 1.5e-13 50.5 1.8 2.4e-13 49.8 1.8 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 KFO98125.1 - 7e-11 42.2 1.9 1.4e-10 41.2 0.6 2.2 2 1 1 3 3 3 1 Hairy Orange CD20 PF04103.15 KFO98126.1 - 7.3e-23 81.4 12.6 9.7e-23 81.0 12.6 1.2 1 0 0 1 1 1 1 CD20-like family DUF1686 PF07937.11 KFO98126.1 - 0.023 14.6 1.0 0.038 13.9 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1686) TcpE PF12648.7 KFO98126.1 - 0.024 15.2 2.5 0.024 15.2 2.5 2.1 2 0 0 2 2 2 0 TcpE family RYDR_ITPR PF01365.21 KFO98127.1 - 3.6e-71 238.8 26.1 1.2e-61 207.7 0.9 4.9 5 0 0 5 5 5 2 RIH domain MIR PF02815.19 KFO98127.1 - 6.2e-70 234.8 0.5 1.2e-66 224.1 0.0 2.9 2 0 0 2 2 2 2 MIR domain Ins145_P3_rec PF08709.11 KFO98127.1 - 3.8e-66 222.3 0.5 3.2e-65 219.3 0.6 2.4 1 1 1 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RIH_assoc PF08454.11 KFO98127.1 - 2.1e-33 114.2 28.0 1e-31 108.8 4.8 5.0 5 0 0 5 5 5 2 RyR and IP3R Homology associated Ion_trans PF00520.31 KFO98127.1 - 1.9e-16 60.1 12.8 4e-16 59.0 12.8 1.5 1 0 0 1 1 1 1 Ion transport protein Sec2p PF06428.11 KFO98127.1 - 0.099 12.6 5.4 0.58 10.2 5.4 2.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF2151 PF10221.9 KFO98129.1 - 8.6e-303 1006.2 4.9 9.9e-303 1006.0 4.9 1.0 1 0 0 1 1 1 1 Cell cycle and development regulator Plk4_PB2 PF18409.1 KFO98129.1 - 0.065 13.9 0.1 0.63 10.8 0.1 2.6 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 SIKE PF05769.11 KFO98130.1 - 1.4e-73 246.7 27.4 1.7e-73 246.4 27.4 1.1 1 0 0 1 1 1 1 SIKE family Tho2 PF11262.8 KFO98130.1 - 0.001 18.3 5.8 0.001 18.3 5.8 2.0 1 1 1 2 2 2 1 Transcription factor/nuclear export subunit protein 2 BST2 PF16716.5 KFO98130.1 - 0.86 10.2 20.6 2.9 8.5 2.4 3.6 3 1 0 3 3 3 0 Bone marrow stromal antigen 2 DUF3829 PF12889.7 KFO98130.1 - 1.1 8.7 13.4 0.071 12.6 1.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) CotJB PF12652.7 KFO98130.1 - 1.5 9.1 4.2 4.2 7.7 0.1 2.7 3 0 0 3 3 3 0 CotJB protein bZIP_1 PF00170.21 KFO98130.1 - 2.2 8.4 23.0 1.6 8.9 1.6 4.4 2 2 1 4 4 4 0 bZIP transcription factor NYD-SP28_assoc PF14775.6 KFO98130.1 - 3.2 7.9 15.5 0.98 9.6 1.9 3.6 3 1 0 3 3 3 0 Sperm tail C-terminal domain Exonuc_VII_L PF02601.15 KFO98130.1 - 3.6 7.1 13.6 5.3 6.5 13.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit FUSC PF04632.12 KFO98130.1 - 3.8 5.9 11.3 4.5 5.7 11.0 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family DASH_Dam1 PF08653.10 KFO98130.1 - 3.9 7.3 5.0 1.5 8.7 0.2 2.6 3 0 0 3 3 3 0 DASH complex subunit Dam1 Mgr1 PF08602.10 KFO98130.1 - 5.1 5.8 10.3 8.1 5.2 9.3 1.9 1 1 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit FIN1 PF17300.2 KFO98130.1 - 6.9 6.1 15.3 0.18 11.3 8.8 1.6 2 0 0 2 2 2 0 Filaments in between nuclei protein-1 DUF4203 PF13886.6 KFO98131.1 - 7.4e-38 130.2 35.0 1e-37 129.8 35.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Med21 PF11221.8 KFO98132.1 - 1.7e-18 67.2 1.2 5.9e-18 65.5 1.2 1.7 1 1 0 1 1 1 1 Subunit 21 of Mediator complex TelA PF05816.11 KFO98132.1 - 0.00074 18.7 0.6 0.00082 18.5 0.6 1.1 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) Pkinase PF00069.25 KFO98133.1 - 3.8e-61 206.8 0.1 1.6e-60 204.7 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO98133.1 - 1.7e-27 96.3 2.3 4e-19 68.9 0.2 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KFO98133.1 - 9.5e-08 32.6 2.0 1.3e-07 32.2 0.9 1.8 2 0 0 2 2 2 1 Protein kinase C terminal domain Kdo PF06293.14 KFO98133.1 - 0.00057 19.3 0.2 0.0011 18.4 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFO98133.1 - 0.00086 18.7 0.4 0.074 12.4 0.1 2.5 2 1 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 KFO98133.1 - 0.001 18.1 0.1 0.0015 17.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFO98133.1 - 0.0015 18.5 0.9 0.21 11.5 0.2 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family PAS_11 PF14598.6 KFO98134.1 - 4.3e-27 94.5 0.1 3.4e-23 81.9 0.1 2.4 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 KFO98134.1 - 3.6e-24 84.9 0.0 4.2e-16 59.0 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 KFO98134.1 - 1.1e-23 83.4 0.0 8.4e-11 41.9 0.0 2.3 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 KFO98134.1 - 1.4e-15 57.0 3.0 2.7e-15 56.1 2.4 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 KFO98134.1 - 3.5e-14 52.9 0.0 2.2e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KFO98134.1 - 6.5e-07 29.6 0.0 0.0056 16.9 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.11 KFO98134.1 - 0.0075 16.9 0.0 0.032 14.9 0.0 1.9 2 0 0 2 2 2 1 PAS fold Pam17 PF08566.10 KFO98134.1 - 0.059 13.2 0.0 0.37 10.6 0.0 2.3 3 0 0 3 3 3 0 Mitochondrial import protein Pam17 Bro-N PF02498.17 KFO98134.1 - 0.088 13.5 0.0 0.82 10.4 0.0 2.4 2 0 0 2 2 2 0 BRO family, N-terminal domain SAM_1 PF00536.30 KFO98135.1 - 4e-39 132.9 10.2 2.5e-17 63.1 0.6 4.1 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFO98135.1 - 1e-33 115.3 8.3 2.3e-14 53.2 0.0 4.2 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) DUF16 PF01519.16 KFO98135.1 - 0.00084 19.8 2.2 0.00084 19.8 2.2 3.3 2 1 0 2 2 2 1 Protein of unknown function DUF16 SAM_PNT PF02198.16 KFO98135.1 - 0.014 15.3 5.5 0.45 10.5 0.9 3.4 3 1 0 3 3 3 0 Sterile alpha motif (SAM)/Pointed domain DUF4041 PF13250.6 KFO98135.1 - 0.38 10.7 2.4 0.63 10.0 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) DUF4407 PF14362.6 KFO98135.1 - 0.4 10.0 17.2 10 5.4 15.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Rab15_effector PF15208.6 KFO98136.1 - 7.3e-125 415.0 0.8 8.1e-125 414.9 0.8 1.0 1 0 0 1 1 1 1 Rab15 effector FAD_binding_6 PF00970.24 KFO98137.1 - 8.9e-37 125.4 0.0 1.3e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KFO98137.1 - 8e-36 123.0 0.0 1.2e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KFO98137.1 - 9.6e-07 29.0 0.0 4.2e-05 23.7 0.0 2.2 1 1 0 2 2 2 1 Ferric reductase NAD binding domain DUF1641 PF07849.11 KFO98137.1 - 0.08 12.8 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) XendoU PF09412.10 KFO98138.1 - 8.8e-104 346.4 0.1 1e-103 346.2 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU EndoU_bacteria PF14436.6 KFO98138.1 - 0.0018 18.6 0.1 0.021 15.1 0.0 2.1 2 0 0 2 2 2 1 Bacterial EndoU nuclease Gb3_synth PF04572.12 KFO98139.1 - 2.2e-47 160.5 2.0 3.2e-47 159.9 2.0 1.3 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.15 KFO98139.1 - 9.2e-21 74.3 0.0 3.4e-20 72.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KFO98139.1 - 0.034 13.5 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Gb3_synth PF04572.12 KFO98140.1 - 8.1e-49 165.1 1.2 1.2e-48 164.6 1.2 1.2 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.15 KFO98140.1 - 6.8e-22 77.9 0.0 1.8e-21 76.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KFO98140.1 - 0.028 13.7 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain HEPN-like_int PF18867.1 KFO98140.1 - 0.18 11.6 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 HEPN-like integron domain ArfGap PF01412.18 KFO98141.1 - 2.3e-27 95.4 1.1 2.3e-27 95.4 1.1 2.5 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf FCH PF00611.23 KFO98142.1 - 6e-16 58.5 0.2 6e-16 58.5 0.2 3.1 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KFO98142.1 - 3.2e-15 55.5 0.1 7e-15 54.4 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFO98142.1 - 1.5e-14 53.5 1.3 2.3e-14 52.9 0.2 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KFO98142.1 - 1e-07 31.5 0.0 2.4e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain NPF PF16601.5 KFO98142.1 - 1.1e-05 26.0 8.3 1.1e-05 26.0 8.3 1.8 2 0 0 2 2 2 1 Rabosyn-5 repeating NPF sequence-motif LIN52 PF10044.9 KFO98142.1 - 0.26 12.0 2.6 0.87 10.3 0.8 2.6 2 0 0 2 2 2 0 Retinal tissue protein DegS PF05384.11 KFO98142.1 - 5.4 6.5 17.8 0.083 12.4 8.0 2.7 3 1 0 3 3 3 0 Sensor protein DegS TTL PF03133.15 KFO98143.1 - 2.9e-111 371.3 0.8 3.8e-111 370.9 0.8 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KFO98143.1 - 3.8e-08 32.9 0.0 0.00027 20.3 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KFO98143.1 - 4e-05 23.0 0.0 0.00088 18.6 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp bcl-2I13 PF12201.8 KFO98144.1 - 3e-05 24.0 0.0 4.2e-05 23.5 0.0 1.3 1 1 0 1 1 1 1 Bcl2-interacting killer, BH3-domain containing Bclx_interact PF08945.10 KFO98144.1 - 0.1 12.4 0.0 0.28 11.0 0.0 1.7 2 0 0 2 2 2 0 Bcl-x interacting, BH3 domain BMF PF15185.6 KFO98144.1 - 0.14 11.9 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis Acyl_transf_1 PF00698.21 KFO98145.1 - 2.5e-12 46.9 0.1 4.7e-12 46.1 0.1 1.3 1 1 0 1 1 1 1 Acyl transferase domain TspO_MBR PF03073.15 KFO98146.1 - 2.7e-49 166.7 12.0 3.1e-49 166.5 12.0 1.0 1 0 0 1 1 1 1 TspO/MBR family DUF1304 PF06993.12 KFO98146.1 - 0.13 12.3 2.7 0.21 11.6 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) TTL PF03133.15 KFO98147.1 - 5.6e-71 239.1 0.1 8.1e-71 238.5 0.1 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family FXa_inhibition PF14670.6 KFO98148.1 - 1.5e-64 214.0 177.3 1.3e-12 47.7 9.1 12.2 12 1 0 12 12 12 9 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFO98148.1 - 7.5e-46 153.7 85.3 2.1e-09 37.2 1.1 12.3 11 1 0 11 11 11 9 Complement Clr-like EGF-like Ephrin_rec_like PF07699.13 KFO98148.1 - 5.2e-36 122.2 34.8 4.2e-15 55.2 8.4 6.7 7 1 1 8 8 8 3 Putative ephrin-receptor like EGF_CA PF07645.15 KFO98148.1 - 2.9e-29 101.0 171.5 2.7e-09 37.1 8.5 11.8 12 0 0 12 12 12 7 Calcium-binding EGF domain EGF_3 PF12947.7 KFO98148.1 - 5.2e-22 77.7 139.9 2.7e-10 40.3 9.5 11.2 10 1 0 10 10 10 8 EGF domain CUB PF00431.20 KFO98148.1 - 4.3e-17 62.5 0.0 4.3e-17 62.5 0.0 2.5 3 0 0 3 3 3 1 CUB domain EGF PF00008.27 KFO98148.1 - 5.7e-14 52.1 143.7 8.9e-06 25.9 5.4 12.3 11 1 2 13 13 13 8 EGF-like domain hEGF PF12661.7 KFO98148.1 - 9.8e-05 22.8 12.6 0.00015 22.2 1.9 12.5 11 1 0 11 11 11 6 Human growth factor-like EGF DUF5398 PF17376.2 KFO98148.1 - 0.068 13.8 0.3 0.19 12.4 0.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5398) DUF4375 PF14300.6 KFO98148.1 - 0.15 12.3 0.2 20 5.5 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4375) Metallophos PF00149.28 KFO98149.1 - 2.1e-11 44.7 0.6 3.2e-11 44.1 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFO98149.1 - 2.1e-07 31.3 0.0 4.9e-06 26.8 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Sulfotransfer_1 PF00685.27 KFO98150.1 - 4e-50 170.8 0.2 5.8e-50 170.2 0.2 1.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFO98150.1 - 7.8e-09 36.2 0.1 1.1e-08 35.7 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase family Peptidase_C92 PF05708.12 KFO98150.1 - 0.0067 16.5 0.0 0.0096 16.0 0.0 1.3 1 0 0 1 1 1 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family DUF758 PF05527.11 KFO98150.1 - 0.042 13.9 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF758) Sulfotransfer_4 PF17784.1 KFO98150.1 - 0.051 13.4 0.2 0.12 12.2 0.2 1.5 1 1 0 1 1 1 0 Sulfotransferase domain NPA PF16469.5 KFO98150.1 - 0.063 13.9 0.1 0.16 12.6 0.1 1.6 1 1 0 1 1 1 0 Nematode polyprotein allergen ABA-1 FdsD PF11390.8 KFO98150.1 - 0.19 12.1 1.4 2.6 8.4 1.5 2.3 1 1 1 2 2 2 0 NADH-dependant formate dehydrogenase delta subunit FdsD Patatin PF01734.22 KFO98151.1 - 1.1e-06 29.0 0.0 2.2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Bac_surface_Ag PF01103.23 KFO98152.1 - 1.9e-62 211.7 3.9 2.2e-62 211.4 3.9 1.0 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 KFO98152.1 - 0.02 15.4 0.1 0.034 14.7 0.1 1.4 1 0 0 1 1 1 0 Surface antigen variable number repeat CH PF00307.31 KFO98153.1 - 6.3e-24 84.3 4.7 5.7e-14 52.2 1.3 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFO98153.1 - 4.2e-05 23.3 0.2 0.01 15.6 0.1 2.5 2 0 0 2 2 2 2 CAMSAP CH domain DUF4264 PF14084.6 KFO98153.1 - 0.036 13.7 0.1 0.097 12.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) Shisa PF13908.6 KFO98154.1 - 3.6e-07 30.6 5.7 3.6e-07 30.6 5.7 2.1 2 0 0 2 2 2 2 Wnt and FGF inhibitory regulator HbrB PF08539.11 KFO98155.1 - 8.2e-16 58.5 0.6 2.7e-14 53.5 0.1 2.2 1 1 1 2 2 2 2 HbrB-like RhoGAP PF00620.27 KFO98156.1 - 5.5e-42 143.2 0.1 1.5e-41 141.8 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 KFO98156.1 - 1.4e-36 125.7 4.2 1.4e-36 125.7 4.2 1.8 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KFO98156.1 - 3.8e-13 49.5 0.6 8.9e-13 48.3 0.6 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain YvbH_ext PF11724.8 KFO98156.1 - 1.3 9.4 5.0 4.4 7.7 1.3 2.5 1 1 1 2 2 2 0 YvbH-like oligomerisation region PHD PF00628.29 KFO98157.1 - 1e-07 31.7 6.7 2.3e-07 30.6 6.7 1.6 1 0 0 1 1 1 1 PHD-finger SH2_2 PF14633.6 KFO98157.1 - 0.048 13.0 0.6 0.11 11.8 0.6 1.5 1 0 0 1 1 1 0 SH2 domain Zf_RING PF16744.5 KFO98157.1 - 0.8 9.9 6.8 4.2 7.6 6.8 2.2 1 1 0 1 1 1 0 KIAA1045 RING finger zf-rbx1 PF12678.7 KFO98157.1 - 2.7 8.4 9.4 6.7 7.1 9.4 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF3736 PF12540.8 KFO98157.1 - 9.3 6.4 10.2 0.42 10.7 1.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3736) Lamprin PF06403.11 KFO98158.1 - 0.029 14.3 0.1 0.091 12.7 0.0 1.6 1 1 1 2 2 2 0 Lamprin Pentapeptide_4 PF13599.6 KFO98158.1 - 0.12 12.5 0.0 0.8 9.9 0.0 1.9 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) Chorion_1 PF01723.16 KFO98158.1 - 6.1 6.8 6.7 55 3.7 6.7 1.9 1 1 0 1 1 1 0 Chorion protein NUP50 PF08911.11 KFO98159.1 - 3.9e-22 78.7 0.9 3.9e-22 78.7 0.9 3.4 4 0 0 4 4 4 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 KFO98159.1 - 5.7e-11 42.7 0.0 1.1e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain DUF2045 PF09741.9 KFO98160.1 - 1.3e-96 322.5 1.1 1.6e-96 322.2 1.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2045) SIR2_2 PF13289.6 KFO98161.1 - 8.6e-18 64.8 0.0 1.7e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 SIR2-like domain RIB43A PF05914.12 KFO98162.1 - 6.1e-126 420.2 54.1 6.8e-126 420.0 54.1 1.0 1 0 0 1 1 1 1 RIB43A EGF_CA PF07645.15 KFO98163.1 - 1.4e-69 230.0 136.6 1.6e-11 44.2 4.5 11.3 11 1 0 12 12 12 9 Calcium-binding EGF domain cEGF PF12662.7 KFO98163.1 - 1e-55 185.2 72.6 3.7e-09 36.3 0.7 11.0 10 0 0 10 10 10 8 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFO98163.1 - 1.6e-25 89.1 135.3 4.8e-07 30.0 6.3 11.2 10 1 0 10 10 10 8 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 KFO98163.1 - 7.6e-17 61.2 110.0 0.00026 21.1 6.2 11.0 10 0 0 10 10 10 9 EGF domain EGF PF00008.27 KFO98163.1 - 1e-05 25.7 118.3 0.0091 16.3 7.7 11.0 10 0 0 10 10 10 6 EGF-like domain ANATO PF01821.18 KFO98163.1 - 0.00086 20.1 5.0 0.00086 20.1 5.0 8.2 8 1 1 9 9 9 1 Anaphylotoxin-like domain hEGF PF12661.7 KFO98163.1 - 0.011 16.3 6.7 0.011 16.3 6.7 12.4 12 1 0 12 12 12 0 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 KFO98163.1 - 0.016 15.5 5.1 0.016 15.5 5.1 9.6 9 1 0 9 9 9 0 Pvs28 EGF domain GBP_PSP PF02425.15 KFO98163.1 - 0.33 10.6 13.3 0.47 10.1 1.4 4.0 3 0 0 3 3 3 0 Paralytic/GBP/PSP peptide Atx10homo_assoc PF09759.9 KFO98164.1 - 1.8e-07 31.1 7.2 0.00021 21.3 0.1 4.4 4 1 1 5 5 5 2 Spinocerebellar ataxia type 10 protein domain 7tm_1 PF00001.21 KFO98165.1 - 3.9e-34 118.2 23.4 4.8e-34 117.9 23.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFO98165.1 - 3.3e-11 43.1 22.5 4.1e-11 42.8 22.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFO98165.1 - 0.0046 16.7 21.5 0.041 13.6 21.5 2.1 1 1 0 1 1 1 1 Olfactory receptor Glycophorin_A PF01102.18 KFO98165.1 - 0.18 12.1 0.6 21 5.4 0.0 2.4 2 0 0 2 2 2 0 Glycophorin A PBC PF03792.13 KFO98166.1 - 7.6e-90 299.8 0.3 1.4e-89 298.9 0.0 1.6 2 0 0 2 2 2 1 PBC domain Homeodomain PF00046.29 KFO98166.1 - 1.8e-18 66.1 0.5 3.8e-18 65.1 0.5 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO98166.1 - 2.8e-15 55.9 0.0 1.1e-14 54.1 0.0 2.0 2 0 0 2 2 2 1 Homeobox KN domain HTH_3 PF01381.22 KFO98166.1 - 0.023 14.7 0.0 0.057 13.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix Sec15 PF04091.12 KFO98166.1 - 0.034 13.6 0.3 0.054 12.9 0.3 1.3 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like NUC130_3NT PF08158.12 KFO98166.1 - 0.31 11.4 1.0 26 5.3 0.1 3.0 3 0 0 3 3 3 0 NUC130/3NT domain DUF2464 PF10240.9 KFO98167.1 - 6.7e-35 120.9 0.0 2.7e-33 115.6 0.0 2.0 1 1 0 1 1 1 1 Multivesicular body subunit 12 E1-E2_ATPase PF00122.20 KFO98168.1 - 0.06 12.9 0.1 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 E1-E2 ATPase CX9C PF16860.5 KFO98169.1 - 1.1e-21 76.6 7.0 2.4e-16 59.4 0.5 2.3 2 1 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 KFO98169.1 - 1.4e-06 28.3 7.3 9.9e-06 25.6 0.8 2.8 2 1 1 3 3 3 2 CHCH domain Cmc1 PF08583.10 KFO98169.1 - 4.5e-05 23.4 6.1 0.0097 15.9 0.4 2.7 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 KFO98169.1 - 0.015 15.0 7.8 0.034 13.9 0.1 2.4 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Ndufs5 PF10200.9 KFO98169.1 - 0.042 14.1 0.5 0.049 13.9 0.5 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Colipase-like PF15083.6 KFO98169.1 - 0.051 13.7 9.1 3 8.0 2.3 2.1 1 1 1 2 2 2 0 Colipase-like GCK PF07802.11 KFO98169.1 - 0.12 12.8 3.7 2.3 8.7 0.3 2.2 1 1 1 2 2 2 0 GCK domain UPF0203 PF05254.12 KFO98169.1 - 0.26 11.6 4.3 5.2 7.4 3.2 2.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Pet191_N PF10203.9 KFO98169.1 - 0.37 11.1 8.9 2.7 8.3 5.4 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 DUF3128 PF11326.8 KFO98169.1 - 1.7 9.1 6.8 5.3 7.5 0.6 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3128) ubiquitin PF00240.23 KFO98170.1 - 2.8e-06 27.0 0.3 8.8e-06 25.4 0.3 1.7 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KFO98170.1 - 0.00029 21.2 0.2 0.0022 18.4 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain ELMO_CED12 PF04727.13 KFO98171.1 - 3.2e-48 164.2 0.4 4.2e-48 163.8 0.4 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family Glyco_transf_54 PF04666.13 KFO98172.1 - 1.7e-121 404.6 0.8 2e-121 404.3 0.8 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Calreticulin PF00262.18 KFO98173.1 - 5.1e-163 542.2 15.3 5.8e-163 542.0 15.3 1.0 1 0 0 1 1 1 1 Calreticulin family DUF2205 PF10224.9 KFO98174.1 - 5e-28 96.9 3.6 6.8e-28 96.5 3.6 1.2 1 0 0 1 1 1 1 Short coiled-coil protein HALZ PF02183.18 KFO98174.1 - 0.0016 18.6 7.8 0.055 13.7 2.5 3.0 1 1 1 2 2 2 2 Homeobox associated leucine zipper YabA PF06156.13 KFO98174.1 - 0.0048 17.5 3.3 0.0062 17.1 3.1 1.4 1 1 0 1 1 1 1 Initiation control protein YabA bZIP_1 PF00170.21 KFO98174.1 - 0.0066 16.5 1.0 0.0066 16.5 1.0 1.7 1 1 1 2 2 2 1 bZIP transcription factor CENP-H PF05837.12 KFO98174.1 - 0.011 16.1 2.8 0.011 16.1 2.8 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) FlaC_arch PF05377.11 KFO98174.1 - 0.019 15.4 1.1 0.019 15.4 1.1 1.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Spectrin PF00435.21 KFO98174.1 - 0.031 14.7 2.8 0.039 14.4 2.8 1.1 1 0 0 1 1 1 0 Spectrin repeat DASH_Dad4 PF08650.10 KFO98174.1 - 0.035 14.1 1.3 0.042 13.8 0.6 1.5 1 1 1 2 2 2 0 DASH complex subunit Dad4 ZapB PF06005.12 KFO98174.1 - 0.042 14.3 6.3 0.071 13.6 6.2 1.4 1 1 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 KFO98174.1 - 0.15 11.9 4.5 0.62 9.9 4.5 2.0 1 1 0 1 1 1 0 Septum formation initiator MAPEG PF01124.18 KFO98176.1 - 2.6e-07 30.6 6.2 3e-07 30.4 6.2 1.1 1 0 0 1 1 1 1 MAPEG family MORN PF02493.20 KFO98177.1 - 7.8e-14 50.7 18.7 0.0015 18.3 0.9 6.4 6 0 0 6 6 6 4 MORN repeat SET PF00856.28 KFO98177.1 - 1.2e-06 29.1 0.0 1.6e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 SET domain MORN_2 PF07661.13 KFO98177.1 - 0.27 11.6 8.6 0.4 11.1 0.0 4.9 6 0 0 6 6 6 0 MORN repeat variant NARP1 PF12569.8 KFO98178.1 - 1.2e-205 684.3 20.4 1.2e-205 684.3 20.4 1.6 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 KFO98178.1 - 1.5e-15 56.0 23.5 0.00051 20.0 0.1 8.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFO98178.1 - 1.8e-13 50.1 8.1 0.039 14.8 0.0 9.1 6 3 3 9 9 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFO98178.1 - 5.1e-12 46.1 18.9 0.004 17.6 0.2 7.5 5 2 4 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFO98178.1 - 6.2e-11 41.6 26.8 0.00038 20.5 0.1 8.7 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFO98178.1 - 4.4e-10 40.0 6.8 0.1 13.3 0.0 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFO98178.1 - 1.2e-09 37.5 23.9 0.0025 17.6 0.2 8.8 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFO98178.1 - 4.8e-08 32.6 6.6 0.00025 20.7 0.1 4.9 6 0 0 6 6 6 2 TPR repeat ANAPC3 PF12895.7 KFO98178.1 - 8.5e-08 32.3 25.9 0.00068 19.8 0.8 6.0 4 2 3 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KFO98178.1 - 4.8e-06 26.8 19.5 0.7 10.2 0.1 7.2 6 3 1 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFO98178.1 - 9.9e-06 25.6 4.3 0.31 11.2 0.2 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 KFO98178.1 - 8.5e-05 22.8 0.1 5.1 8.0 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFO98178.1 - 0.00018 21.3 12.3 1.2 9.4 0.1 7.3 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFO98178.1 - 0.001 18.4 3.0 0.001 18.4 3.0 3.9 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFO98178.1 - 0.0028 18.2 11.0 12 6.8 0.0 7.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_3 PF07720.12 KFO98178.1 - 0.053 13.5 1.8 18 5.5 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat BT1 PF03092.16 KFO98178.1 - 0.12 10.5 0.0 0.21 9.8 0.0 1.3 1 0 0 1 1 1 0 BT1 family TPR_10 PF13374.6 KFO98178.1 - 0.14 12.0 9.8 1.4e+02 2.5 0.0 6.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFO98178.1 - 0.93 9.6 10.5 23 5.1 0.1 5.0 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat F-protein PF00469.20 KFO98178.1 - 1.2 8.7 7.4 1.3 8.6 5.4 1.9 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef TPR_17 PF13431.6 KFO98178.1 - 2.9 8.5 14.8 5.8 7.5 0.0 7.2 9 0 0 9 9 6 0 Tetratricopeptide repeat PPR PF01535.20 KFO98178.1 - 6.3 7.3 10.1 6.5 7.2 0.0 5.8 7 0 0 7 7 6 0 PPR repeat DUF3464 PF11947.8 KFO98178.1 - 6.7 6.5 8.3 12 5.6 8.3 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 TMEM51 PF15345.6 KFO98178.1 - 7.7 6.3 6.2 13 5.5 6.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Elf-1_N PF12310.8 KFO98180.1 - 5.1e-41 139.7 3.7 5.1e-41 139.7 3.7 2.5 3 0 0 3 3 3 1 Transcription factor protein N terminal Ets PF00178.22 KFO98180.1 - 1.9e-34 118.0 1.2 3e-34 117.3 1.2 1.3 1 0 0 1 1 1 1 Ets-domain Exo_endo_phos PF03372.23 KFO98181.1 - 2.8e-24 85.9 0.0 3.6e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KFO98181.1 - 0.0024 17.7 0.0 0.016 15.0 0.0 2.4 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase E3_UbLigase_EDD PF11547.8 KFO98181.1 - 0.022 14.5 0.6 0.62 9.8 0.1 2.7 3 0 0 3 3 3 0 E3 ubiquitin ligase EDD AA_permease_2 PF13520.6 KFO98182.1 - 1.8e-60 205.0 42.1 2.2e-60 204.7 42.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFO98182.1 - 1.1e-30 106.7 39.8 1.8e-30 106.0 39.8 1.3 1 1 0 1 1 1 1 Amino acid permease Cadherin PF00028.17 KFO98183.1 - 1e-85 282.3 2.4 4.9e-18 65.4 0.0 6.5 5 1 1 6 6 6 6 Cadherin domain Cadherin_2 PF08266.12 KFO98183.1 - 1.1e-14 54.0 1.2 4.2e-13 48.9 0.1 3.8 5 0 0 5 5 5 1 Cadherin-like Cadherin_3 PF16184.5 KFO98183.1 - 7.6e-06 25.9 7.6 0.29 11.1 0.3 5.2 4 1 1 5 5 5 3 Cadherin-like Cadherin_C_2 PF16492.5 KFO98183.1 - 0.00069 20.3 0.8 0.0035 18.0 0.8 2.4 1 1 0 1 1 1 1 Cadherin cytoplasmic C-terminal FAM176 PF14851.6 KFO98183.1 - 0.011 15.4 3.4 0.011 15.4 1.0 2.1 2 0 0 2 2 2 0 FAM176 family VEGF_C PF14554.6 KFO98183.1 - 0.013 15.6 0.0 0.031 14.4 0.0 1.6 1 0 0 1 1 1 0 VEGF heparin-binding domain Syndecan PF01034.20 KFO98183.1 - 0.074 13.0 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Syndecan domain Glypican PF01153.19 KFO98185.1 - 3.5e-206 686.4 0.0 4e-206 686.1 0.0 1.0 1 0 0 1 1 1 1 Glypican Fz PF01392.22 KFO98185.1 - 0.059 14.0 0.3 0.13 12.9 0.3 1.5 1 0 0 1 1 1 0 Fz domain Tyrosinase PF00264.20 KFO98187.1 - 1.7e-30 107.0 0.0 2.7e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase GDP_Man_Dehyd PF16363.5 KFO98188.1 - 6.7e-66 222.9 0.1 7.6e-66 222.8 0.1 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFO98188.1 - 4.3e-55 186.8 0.1 5.3e-55 186.5 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFO98188.1 - 5.8e-24 84.7 0.0 7.1e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KFO98188.1 - 3e-23 82.4 0.0 1.2e-22 80.4 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KFO98188.1 - 6.1e-20 71.4 0.1 8.9e-20 70.8 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KFO98188.1 - 3.5e-15 55.9 0.0 5.8e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KFO98188.1 - 9.1e-06 25.7 0.0 1.4e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GpcrRhopsn4 PF10192.9 KFO98189.1 - 1.3e-79 267.2 6.0 1.6e-79 267.0 6.0 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 KFO98189.1 - 2.3e-07 30.4 4.9 3e-07 30.0 4.4 1.4 1 1 0 1 1 1 1 Lung seven transmembrane receptor PLAC8 PF04749.17 KFO98189.1 - 0.0024 18.8 1.5 0.0024 18.8 1.5 2.4 3 0 0 3 3 3 1 PLAC8 family DUF1146 PF06612.11 KFO98189.1 - 0.0066 16.5 0.2 0.025 14.6 0.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1146) WHIM1 PF15612.6 KFO98189.1 - 0.027 14.0 0.1 0.094 12.3 0.1 1.9 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 DUF2567 PF10821.8 KFO98189.1 - 0.07 13.2 0.2 0.59 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2567) ABC_membrane PF00664.23 KFO98190.1 - 9e-63 212.5 37.8 2.1e-31 109.6 11.2 2.4 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFO98190.1 - 1.5e-55 187.5 0.1 1e-29 103.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFO98190.1 - 6.4e-12 45.4 2.1 0.014 14.9 0.0 4.3 3 1 0 4 4 4 4 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KFO98190.1 - 1.4e-07 31.6 0.1 0.0056 16.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KFO98190.1 - 1.8e-07 31.7 1.4 0.012 16.0 0.1 3.1 3 1 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 KFO98190.1 - 6.9e-07 28.9 0.0 0.032 14.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFO98190.1 - 1.7e-06 28.0 0.0 0.02 14.8 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KFO98190.1 - 4.7e-06 26.9 1.0 0.22 11.8 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_21 PF13304.6 KFO98190.1 - 8.3e-06 25.8 0.8 0.1 12.4 0.1 3.3 3 1 1 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 KFO98190.1 - 1.6e-05 25.1 0.4 0.017 15.1 0.0 2.7 2 1 0 2 2 2 2 Dynamin family IstB_IS21 PF01695.17 KFO98190.1 - 0.0004 20.2 0.8 0.93 9.2 0.0 3.8 4 1 0 4 4 4 1 IstB-like ATP binding protein AAA_23 PF13476.6 KFO98190.1 - 0.00047 20.7 0.0 0.36 11.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KFO98190.1 - 0.00049 19.7 0.0 1 8.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF87 PF01935.17 KFO98190.1 - 0.0023 18.1 0.5 0.25 11.4 0.0 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain T2SSE PF00437.20 KFO98190.1 - 0.0024 17.0 0.0 0.044 12.8 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 KFO98190.1 - 0.0043 16.8 0.3 1.8 8.2 0.1 3.0 2 1 0 2 2 2 1 AAA domain cobW PF02492.19 KFO98190.1 - 0.029 13.9 0.2 3 7.4 0.1 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 KFO98190.1 - 0.043 13.0 0.2 3.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_PrkA PF08298.11 KFO98190.1 - 0.087 11.7 0.1 1.1 8.0 0.0 2.6 3 0 0 3 3 3 0 PrkA AAA domain Guanylate_kin PF00625.21 KFO98190.1 - 0.11 12.2 0.1 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Guanylate kinase AAA_27 PF13514.6 KFO98190.1 - 0.11 12.0 0.0 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KFO98190.1 - 0.14 12.4 0.2 11 6.2 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 KFO98190.1 - 0.15 11.4 0.2 13 5.0 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin MeaB PF03308.16 KFO98190.1 - 0.2 10.6 0.4 6.6 5.6 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dzip-like_N PF13815.6 KFO98191.1 - 8.4e-35 119.3 0.2 8.4e-35 119.3 0.2 6.1 4 2 2 6 6 6 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF3800 PF12686.7 KFO98191.1 - 0.029 15.0 0.9 1.9e+02 2.7 0.0 3.4 2 2 0 2 2 2 0 Protein of unknown function (DUF3800) Herpes_glycoH_C PF17488.2 KFO98191.1 - 0.037 13.8 0.4 0.11 12.3 0.4 1.7 1 0 0 1 1 1 0 Herpesvirus glycoprotein H C-terminal domain zf-C2H2_6 PF13912.6 KFO98191.1 - 0.05 13.6 2.5 0.096 12.7 2.5 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KFO98191.1 - 0.2 12.6 9.5 0.079 13.8 3.4 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KFO98191.1 - 1 10.0 13.1 0.54 10.9 5.3 3.4 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2 PF00096.26 KFO98191.1 - 2.7 8.6 11.5 0.047 14.2 3.4 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type SlyX PF04102.12 KFO98191.1 - 4.2 8.1 34.9 2.9 8.6 6.7 5.9 3 1 2 5 5 5 0 SlyX TPR_2 PF07719.17 KFO98192.1 - 3.8e-30 101.6 24.7 0.00023 21.0 0.0 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_1 PF00515.28 KFO98192.1 - 1.7e-29 100.4 26.0 7.1e-07 28.8 0.0 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 KFO98192.1 - 1.1e-26 93.1 19.9 1.5e-06 28.6 1.3 6.8 3 3 3 6 6 6 6 Tetratricopeptide repeat TPR_16 PF13432.6 KFO98192.1 - 5.8e-22 78.1 9.9 0.00031 21.3 0.8 6.5 4 2 2 6 6 6 5 Tetratricopeptide repeat DnaJ PF00226.31 KFO98192.1 - 2.7e-21 75.5 2.2 2.7e-21 75.5 2.2 3.5 4 0 0 4 4 4 1 DnaJ domain TPR_11 PF13414.6 KFO98192.1 - 3.7e-21 74.5 21.4 2e-05 24.2 0.6 8.0 6 1 2 8 8 8 6 TPR repeat TPR_8 PF13181.6 KFO98192.1 - 1.3e-20 71.8 25.7 0.0002 21.3 0.1 9.1 8 1 1 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.6 KFO98192.1 - 2.3e-19 68.4 14.9 0.018 15.9 0.0 9.8 6 3 4 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.6 KFO98192.1 - 1.6e-17 63.4 7.7 1e-05 25.6 0.4 5.4 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFO98192.1 - 6.3e-13 48.8 23.1 0.02 15.2 0.1 7.8 3 2 5 8 8 8 7 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO98192.1 - 4.4e-12 46.1 23.9 8.5e-05 22.7 1.1 5.4 2 1 2 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KFO98192.1 - 3.2e-11 42.8 11.0 0.013 15.8 0.0 7.0 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFO98192.1 - 4e-11 42.8 19.1 0.48 11.2 0.2 9.8 10 1 0 10 10 9 2 Tetratricopeptide repeat TPR_20 PF14561.6 KFO98192.1 - 1.6e-08 34.8 24.5 0.22 11.9 0.1 7.6 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFO98192.1 - 5e-08 32.4 13.6 4.5 7.5 0.0 8.2 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 KFO98192.1 - 4.6e-05 22.8 17.0 0.081 12.1 1.1 5.8 1 1 4 6 6 6 2 Tetratricopeptide repeat COPI_C PF06957.11 KFO98192.1 - 0.00024 20.0 0.7 0.31 9.7 0.0 3.2 2 2 2 4 4 4 2 Coatomer (COPI) alpha subunit C-terminus Fis1_TPR_C PF14853.6 KFO98192.1 - 0.00059 19.9 12.8 0.4 10.8 0.5 6.0 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KFO98192.1 - 0.011 15.6 10.0 2.6 8.1 0.0 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat BTAD PF03704.17 KFO98192.1 - 0.017 15.5 14.6 5.9 7.3 1.5 5.3 3 1 1 4 4 4 0 Bacterial transcriptional activator domain Alkyl_sulf_dimr PF14863.6 KFO98192.1 - 0.047 14.1 14.4 1.5 9.3 0.6 5.1 1 1 2 5 5 5 0 Alkyl sulfatase dimerisation TPR_4 PF07721.14 KFO98192.1 - 0.38 11.5 12.6 1.2 10.0 0.0 5.7 7 0 0 7 7 6 0 Tetratricopeptide repeat Glyco_transf_24 PF18404.1 KFO98193.1 - 6.8e-148 491.3 3.8 1.6e-147 490.1 3.8 1.7 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_15 PF18403.1 KFO98193.1 - 2.2e-65 220.6 1.4 7.5e-63 212.3 0.6 3.1 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_14 PF18402.1 KFO98193.1 - 1.4e-62 211.9 1.9 2.3e-58 198.2 0.1 3.6 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KFO98193.1 - 2.4e-42 145.0 0.3 5.3e-42 143.9 0.3 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KFO98193.1 - 7.2e-40 135.5 0.0 2.4e-39 133.8 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 KFO98193.1 - 8.2e-38 129.4 0.2 4.3e-37 127.1 0.1 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 KFO98193.1 - 1.7e-06 27.8 0.6 1.7e-06 27.8 0.6 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 8 YusW PF14039.6 KFO98193.1 - 1.5 9.4 5.3 0.52 10.8 0.2 2.8 2 0 0 2 2 2 0 YusW-like protein Sulfotransfer_2 PF03567.14 KFO98194.1 - 3.2e-50 171.4 1.3 3.2e-50 171.4 1.3 1.6 2 0 0 2 2 2 1 Sulfotransferase family RNA_pol_Rbc25 PF08292.12 KFO98194.1 - 0.12 12.6 0.2 0.18 12.0 0.2 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 7tm_1 PF00001.21 KFO98195.1 - 9.4e-33 113.6 26.8 1.2e-32 113.2 26.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-CCCH PF00642.24 KFO98196.1 - 7.2e-11 41.7 24.8 0.00018 21.3 0.7 5.4 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KFO98196.1 - 2e-06 28.0 24.8 0.24 11.9 1.5 4.7 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KFO98196.1 - 2.4e-06 27.7 12.7 0.012 15.8 1.4 2.9 2 1 0 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 KFO98196.1 - 9.8e-05 22.1 1.4 9.8e-05 22.1 1.4 5.3 5 2 0 5 5 5 3 CCCH-type zinc finger Torus PF16131.5 KFO98196.1 - 0.00047 20.8 21.2 0.29 11.8 0.3 4.6 2 2 2 4 4 4 3 Torus domain zf_CCCH_4 PF18345.1 KFO98196.1 - 0.002 18.1 37.6 0.042 13.9 2.6 7.7 5 4 0 5 5 5 2 Zinc finger domain Methyltransf_16 PF10294.9 KFO98197.1 - 1.5e-21 76.9 1.0 1.1e-19 70.8 1.0 2.2 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KFO98197.1 - 0.008 16.9 0.7 0.038 14.7 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFO98197.1 - 0.016 15.1 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF2321 PF10083.9 KFO98197.1 - 0.039 13.6 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) PrmA PF06325.13 KFO98197.1 - 0.063 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Aminotran_3 PF00202.21 KFO98198.1 - 4.4e-135 450.4 0.0 5.1e-135 450.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KFO98198.1 - 0.088 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II TMEM223 PF14640.6 KFO98199.1 - 2.1e-06 28.0 0.1 2.2e-06 27.9 0.1 1.1 1 0 0 1 1 1 1 Transmembrane protein 223 PMM PF03332.13 KFO98200.1 - 1.3e-68 231.1 0.8 1.4e-68 231.0 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase DUF600 PF04634.12 KFO98200.1 - 0.077 13.1 0.1 0.17 12.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF600 T2SSG PF08334.11 KFO98200.1 - 0.13 12.3 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G CSD PF00313.22 KFO98201.1 - 3.5e-13 49.2 0.0 4.8e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KFO98201.1 - 0.0096 15.6 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease B OB domain USP7_ICP0_bdg PF12436.8 KFO98202.1 - 4.9e-76 255.2 0.0 3.8e-75 252.3 0.0 2.3 2 1 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KFO98202.1 - 6.2e-65 218.8 4.3 3e-62 210.0 2.8 3.2 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 KFO98202.1 - 6.7e-50 170.0 0.3 1.2e-49 169.2 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFO98202.1 - 8.3e-18 65.0 0.0 2.8e-17 63.3 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KFO98202.1 - 8.9e-16 58.1 1.5 1.3e-14 54.3 0.2 2.9 2 1 1 3 3 3 1 MATH domain DUF4588 PF15251.6 KFO98203.1 - 1.6e-54 185.3 0.0 1.8e-54 185.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) NMDAR2_C PF10565.9 KFO98204.1 - 1.6e-261 870.0 37.9 1.9e-261 869.7 37.9 1.1 1 0 0 1 1 1 1 N-methyl D-aspartate receptor 2B3 C-terminus Lig_chan PF00060.26 KFO98204.1 - 1.3e-34 119.2 2.6 1.6e-34 118.9 0.1 2.4 3 0 0 3 3 3 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFO98204.1 - 2.5e-30 105.0 0.1 1.2e-29 102.8 0.1 2.1 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFO98204.1 - 4.7e-21 75.3 0.0 2.6e-20 72.8 0.0 2.0 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 KFO98204.1 - 6.1e-07 28.9 0.3 3.2e-06 26.5 0.3 2.1 1 1 0 1 1 1 1 Receptor family ligand binding region Cript PF10235.9 KFO98204.1 - 0.53 10.9 8.4 0.23 12.0 1.2 3.0 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT PMP22_Claudin PF00822.20 KFO98205.1 - 2.3e-48 164.2 16.0 2.6e-48 164.0 16.0 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFO98205.1 - 4.6e-11 42.8 9.1 4.6e-11 42.8 9.1 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.12 KFO98205.1 - 4.2e-05 23.3 9.3 4.2e-05 23.3 9.3 2.8 1 1 0 2 2 2 1 SUR7/PalI family Claudin_3 PF06653.11 KFO98205.1 - 0.00085 19.3 17.8 0.0018 18.2 17.8 1.5 1 1 0 1 1 1 1 Tight junction protein, Claudin-like Amastin PF07344.11 KFO98205.1 - 0.0012 18.7 11.8 0.0025 17.7 11.8 1.6 1 1 0 1 1 1 1 Amastin surface glycoprotein DUF2721 PF11026.8 KFO98205.1 - 0.025 14.5 2.6 0.025 14.5 2.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) DUF4131 PF13567.6 KFO98205.1 - 0.055 13.1 0.3 0.055 13.1 0.3 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) HisKA_7TM PF16927.5 KFO98205.1 - 0.49 10.4 12.3 1.1 9.2 12.3 1.7 1 1 0 1 1 1 0 N-terminal 7TM region of histidine kinase DUF3852 PF12963.7 KFO98205.1 - 0.83 10.0 8.1 0.064 13.6 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3852) DUF4328 PF14219.6 KFO98205.1 - 1.2 8.7 6.6 0.11 12.1 1.3 1.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4328) 7TMR-DISM_7TM PF07695.11 KFO98205.1 - 1.6 8.6 18.4 11 5.9 17.0 2.2 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF5090 PF17009.5 KFO98205.1 - 1.8 8.5 10.3 2.9 7.8 10.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) ParA PF10609.9 KFO98206.1 - 2.2e-88 295.9 0.0 2.4e-88 295.7 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 KFO98206.1 - 0.024 14.1 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.6 KFO98206.1 - 0.062 13.2 0.0 0.099 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain TF_Zn_Ribbon PF08271.12 KFO98206.1 - 0.11 12.0 0.1 0.27 10.8 0.1 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding AAA_26 PF13500.6 KFO98206.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KFO98206.1 - 0.13 12.3 0.0 0.38 10.8 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PcrB PF01884.17 KFO98206.1 - 0.19 11.1 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 PcrB family DUF846 PF05832.12 KFO98207.1 - 2.8e-53 179.7 15.1 3.2e-53 179.5 15.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) STAT2_C PF12188.8 KFO98208.1 - 0.011 15.7 0.4 0.025 14.5 0.4 1.6 1 0 0 1 1 1 0 Signal transducer and activator of transcription 2 C terminal NACHT PF05729.12 KFO98209.1 - 3.5e-31 108.4 0.0 7.8e-31 107.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain LRR_6 PF13516.6 KFO98209.1 - 1.4e-16 59.0 10.1 4.2e-05 23.3 0.1 6.2 5 1 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.7 KFO98209.1 - 5e-12 45.8 6.5 1.9e-06 28.1 0.8 5.3 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) NLRC4_HD2 PF17776.1 KFO98209.1 - 1.5e-11 45.0 2.4 1.5e-11 45.0 2.4 2.5 3 0 0 3 3 3 1 NLRC4 helical domain HD2 LRR_9 PF14580.6 KFO98209.1 - 7.8e-06 25.5 0.0 3.2e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 KFO98209.1 - 2.2e-05 24.4 0.3 22 6.1 0.0 5.6 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 KFO98209.1 - 3.5e-05 23.5 7.0 0.00038 20.2 2.2 4.3 3 1 2 5 5 5 2 Leucine rich repeat PKS_DE PF18369.1 KFO98209.1 - 0.00066 20.2 1.4 1.1 9.9 0.2 3.5 3 0 0 3 3 3 1 Polyketide synthase dimerisation element domain LRR_2 PF07723.13 KFO98209.1 - 0.099 13.3 4.3 7.6 7.4 0.0 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat Dexa_ind PF15198.6 KFO98210.1 - 2.2e-43 146.3 10.3 2.4e-43 146.1 10.3 1.0 1 0 0 1 1 1 1 Dexamethasone-induced FPL PF09758.9 KFO98211.1 - 1.4e-62 210.0 11.9 3.1e-62 208.9 11.9 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein SH2 PF00017.24 KFO98212.1 - 7.3e-10 38.8 0.0 1.4e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.16 KFO98212.1 - 2.3e-07 31.1 0.0 4.5e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 SOCS box RMI2 PF16100.5 KFO98213.1 - 4.4e-21 75.0 0.1 4.8e-21 74.9 0.1 1.0 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 zf-LITAF-like PF10601.9 KFO98215.1 - 4e-26 91.1 10.8 5.1e-26 90.7 10.8 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-C4_Topoisom PF01396.19 KFO98215.1 - 0.029 14.1 3.7 1.1 9.1 0.6 2.4 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-ISL3 PF14690.6 KFO98215.1 - 0.03 15.0 1.9 3.8 8.3 0.2 2.4 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-ACC PF17848.1 KFO98215.1 - 0.34 11.0 5.8 6.7 6.9 1.5 2.5 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain SNN_transmemb PF09049.10 KFO98216.1 - 2.9e-23 81.5 8.6 3.7e-23 81.2 8.6 1.1 1 0 0 1 1 1 1 Stannin transmembrane SNN_cytoplasm PF09051.10 KFO98216.1 - 4.2e-21 74.5 0.5 5.5e-21 74.1 0.5 1.2 1 0 0 1 1 1 1 Stannin cytoplasmic SNN_linker PF09050.10 KFO98216.1 - 2.1e-20 72.2 2.8 2.9e-20 71.7 2.8 1.2 1 0 0 1 1 1 1 Stannin unstructured linker DUF5337 PF17272.2 KFO98216.1 - 0.033 14.0 0.0 0.044 13.6 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5337) LapA_dom PF06305.11 KFO98216.1 - 0.061 13.1 0.1 0.085 12.7 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF202 PF02656.15 KFO98216.1 - 0.12 12.8 0.5 0.15 12.5 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Thioredoxin PF00085.20 KFO98217.1 - 2.3e-23 82.1 0.0 3.3e-11 43.1 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 KFO98217.1 - 3.4e-06 27.1 0.4 0.06 13.2 0.0 3.9 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFO98217.1 - 1.5e-05 25.1 1.0 0.024 14.8 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KFO98217.1 - 6.9e-05 23.1 1.5 0.047 14.0 0.1 3.6 3 0 0 3 3 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KFO98217.1 - 0.0062 17.0 0.6 5.2 7.6 0.1 3.7 3 1 0 3 3 3 1 Thioredoxin-like domain Tho2 PF11262.8 KFO98217.1 - 0.12 11.5 11.3 0.23 10.6 11.3 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Redoxin PF08534.10 KFO98217.1 - 0.12 12.0 0.0 9.2 6.0 0.0 2.8 3 0 0 3 3 3 0 Redoxin GPS2_interact PF15784.5 KFO98217.1 - 0.19 12.2 10.4 0.067 13.6 6.8 2.2 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain Macoilin PF09726.9 KFO98217.1 - 0.76 8.3 23.4 0.084 11.4 18.2 1.5 1 1 0 1 1 1 0 Macoilin family DUF641 PF04859.12 KFO98217.1 - 0.77 10.1 16.9 7.1 7.0 8.2 2.7 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) ERM PF00769.19 KFO98217.1 - 0.96 9.2 33.2 1.3 8.7 33.2 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Exonuc_VII_L PF02601.15 KFO98217.1 - 2.8 7.4 16.2 4.9 6.6 16.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 KFO98217.1 - 3.3 6.9 13.0 5.7 6.1 13.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein FUSC PF04632.12 KFO98217.1 - 3.9 5.9 9.5 6.6 5.1 9.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMF_TATA_bd PF12325.8 KFO98217.1 - 4.1 7.6 25.1 0.46 10.7 19.4 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.6 KFO98217.1 - 5.4 6.3 15.5 8.8 5.6 15.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 KFO98217.1 - 8.9 6.4 10.7 22 5.1 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TPR_1 PF00515.28 KFO98218.1 - 5.4e-08 32.3 3.5 0.004 16.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFO98218.1 - 4.3e-06 26.4 1.3 0.39 11.0 0.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-CCCH PF00642.24 KFO98218.1 - 6.3e-05 22.8 2.0 6.3e-05 22.8 2.0 4.3 4 0 0 4 4 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFO98218.1 - 0.00016 21.6 2.0 0.00016 21.6 2.0 4.0 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_4 PF18044.1 KFO98218.1 - 0.00018 21.2 1.0 0.00018 21.2 1.0 4.9 4 0 0 4 4 4 1 CCCH-type zinc finger zf-C2H2_jaz PF12171.8 KFO98218.1 - 0.00048 20.3 6.7 0.0019 18.4 6.7 2.1 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding TPR_11 PF13414.6 KFO98218.1 - 0.028 14.1 0.3 6.6 6.5 0.0 2.5 2 0 0 2 2 2 0 TPR repeat zf-met PF12874.7 KFO98218.1 - 0.031 14.7 6.3 0.098 13.1 6.3 2.0 1 0 0 1 1 1 0 Zinc-finger of C2H2 type TPR_17 PF13431.6 KFO98218.1 - 0.04 14.3 0.3 0.11 12.9 0.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFO98218.1 - 0.042 14.4 0.5 0.12 12.9 0.4 1.8 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFO98218.1 - 0.05 13.9 1.7 13 6.1 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO98218.1 - 0.066 13.4 2.3 0.27 11.5 2.3 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KFO98218.1 - 0.082 13.2 0.5 0.37 11.1 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Phospholip_A2_1 PF00068.19 KFO98219.1 - 4.6e-36 123.7 15.2 5.2e-36 123.5 15.2 1.0 1 0 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.10 KFO98219.1 - 0.025 14.7 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 Parvovirus coat protein VP1 SAM_1 PF00536.30 KFO98220.1 - 3.7e-12 46.5 0.1 7.6e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C3HC4_4 PF15227.6 KFO98220.1 - 6.1e-08 32.7 14.5 7.4e-08 32.4 12.5 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KFO98220.1 - 6.8e-08 32.2 13.3 1.6e-07 31.0 13.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFO98220.1 - 7.2e-08 32.2 13.8 1.4e-07 31.2 13.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SAM_2 PF07647.17 KFO98220.1 - 1.1e-07 31.8 0.1 2.1e-07 30.9 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C3HC4_3 PF13920.6 KFO98220.1 - 2.1e-06 27.5 8.1 3.6e-06 26.7 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFO98220.1 - 5e-06 26.4 11.2 1.4e-05 25.0 11.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFO98220.1 - 3.6e-05 24.0 14.6 7.3e-05 23.0 14.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 KFO98220.1 - 0.02 14.7 5.0 0.02 14.7 5.0 2.6 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain DUF1435 PF07256.12 KFO98220.1 - 0.023 14.8 0.7 0.36 10.9 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1435) zf-ANAPC11 PF12861.7 KFO98220.1 - 0.029 14.4 4.9 0.074 13.1 4.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SAM_PNT PF02198.16 KFO98220.1 - 0.031 14.2 0.2 0.099 12.6 0.2 1.8 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain zf-RING_5 PF14634.6 KFO98220.1 - 0.034 14.1 11.5 0.073 13.0 11.5 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 KFO98220.1 - 0.052 13.8 11.0 0.12 12.7 11.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFO98220.1 - 0.067 13.1 10.3 0.16 11.9 10.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KFO98220.1 - 0.28 11.4 8.2 0.24 11.5 6.6 1.7 2 0 0 2 2 1 0 zinc RING finger of MSL2 CAF1 PF04857.20 KFO98221.1 - 1.8e-88 296.8 2.7 1.8e-88 296.8 2.7 1.9 2 0 0 2 2 2 1 CAF1 family ribonuclease RNA_bind PF08675.11 KFO98221.1 - 1.4e-33 114.7 0.2 2.8e-33 113.8 0.2 1.5 1 0 0 1 1 1 1 RNA binding domain R3H PF01424.22 KFO98221.1 - 1.9e-06 27.7 0.0 6e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 R3H domain NCBP3 PF10309.9 KFO98221.1 - 0.015 15.1 0.1 0.035 14.0 0.1 1.6 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 RRM_1 PF00076.22 KFO98221.1 - 0.033 14.0 0.0 0.086 12.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VIT PF08487.10 KFO98221.1 - 0.065 13.5 1.2 0.65 10.2 0.0 2.6 2 0 0 2 2 2 0 Vault protein inter-alpha-trypsin domain Shisa PF13908.6 KFO98222.1 - 1.2e-40 139.8 1.0 1.5e-40 139.5 1.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Chordopox_A13L PF05961.11 KFO98222.1 - 0.096 12.9 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Metallophos PF00149.28 KFO98223.1 - 6.4e-14 52.9 2.4 8.9e-14 52.5 2.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PX PF00787.24 KFO98224.1 - 1.5e-18 66.8 1.1 1.5e-18 66.8 1.1 2.2 3 0 0 3 3 3 1 PX domain kleA_kleC PF17383.2 KFO98224.1 - 0.035 14.4 1.5 0.087 13.2 1.5 1.7 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A TSC22 PF01166.18 KFO98224.1 - 0.097 13.0 9.9 0.12 12.6 1.3 3.0 1 1 1 2 2 2 0 TSC-22/dip/bun family PRiA4_ORF3 PF07929.11 KFO98224.1 - 0.21 11.3 1.9 12 5.5 0.0 2.4 2 0 0 2 2 2 0 Plasmid pRiA4b ORF-3-like protein FUSC PF04632.12 KFO98224.1 - 0.41 9.1 2.2 0.55 8.7 2.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phage_GP20 PF06810.11 KFO98224.1 - 0.47 10.2 4.6 0.13 12.1 0.5 2.0 3 0 0 3 3 3 0 Phage minor structural protein GP20 PXA PF02194.15 KFO98224.1 - 1.1 9.2 4.4 5.6 6.9 4.4 2.1 1 1 0 1 1 1 0 PXA domain BRE1 PF08647.11 KFO98224.1 - 1.3 9.2 8.5 0.63 10.2 2.6 3.2 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase MCD_N PF17408.2 KFO98224.1 - 1.8 8.8 4.7 8.9 6.5 0.2 3.4 3 0 0 3 3 3 0 Malonyl-CoA decarboxylase N-terminal domain ALMT PF11744.8 KFO98224.1 - 1.8 7.3 5.2 3 6.6 5.2 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter bZIP_1 PF00170.21 KFO98224.1 - 4.4 7.5 14.0 1.5 9.0 1.1 3.2 3 0 0 3 3 3 0 bZIP transcription factor NYD-SP28_assoc PF14775.6 KFO98224.1 - 4.7 7.4 12.2 2.2 8.4 0.8 3.6 4 0 0 4 4 4 0 Sperm tail C-terminal domain Atg14 PF10186.9 KFO98224.1 - 7.2 5.6 7.7 2.6 7.0 3.7 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 RUN PF02759.19 KFO98225.1 - 7e-25 87.6 0.1 1.3e-24 86.7 0.1 1.5 1 0 0 1 1 1 1 RUN domain UPF0054 PF02130.17 KFO98225.1 - 0.0087 15.9 0.2 0.024 14.4 0.1 1.9 2 0 0 2 2 2 1 Uncharacterized protein family UPF0054 GTP_EFTU PF00009.27 KFO98226.1 - 6.9e-47 159.5 0.0 1.4e-46 158.5 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFO98226.1 - 3.4e-32 111.1 0.2 3.4e-32 111.1 0.2 2.8 5 0 0 5 5 5 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KFO98226.1 - 2e-08 34.5 0.1 8e-08 32.6 0.1 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFO98226.1 - 0.0006 19.9 0.1 0.0028 17.7 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase LPD34 PF18852.1 KFO98226.1 - 0.058 13.0 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 34 Arf PF00025.21 KFO98226.1 - 0.06 12.8 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Ribosomal_L1 PF00687.21 KFO98227.1 - 1.1e-52 178.7 1.0 1.3e-52 178.5 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family RRN3 PF05327.11 KFO98228.1 - 3.1e-133 445.3 0.5 3.9e-133 444.9 0.5 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 GP24_25 PF17388.2 KFO98228.1 - 0.06 13.3 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 Tail assembly gene products 24 & 25 N_Asn_amidohyd PF14736.6 KFO98229.1 - 5.2e-113 376.7 0.0 5.9e-113 376.5 0.0 1.0 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase A2M_recep PF07677.14 KFO98229.1 - 0.071 13.8 0.0 0.16 12.7 0.0 1.5 1 0 0 1 1 1 0 A-macroglobulin receptor binding domain Pyridoxal_deC PF00282.19 KFO98230.1 - 2.6e-12 46.2 0.0 2.1e-09 36.6 0.0 2.2 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain KIAA1430 PF13879.6 KFO98230.1 - 3.1 8.6 8.4 23 5.8 0.2 3.7 3 0 0 3 3 3 0 KIAA1430 homologue DUF948 PF06103.11 KFO98230.1 - 5.1 7.4 5.7 25 5.2 0.2 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3585 PF12130.8 KFO98231.1 - 5.1e-18 65.5 17.3 6.9e-18 65.1 17.3 1.2 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain DUF572 PF04502.13 KFO98231.1 - 0.026 14.2 4.4 0.031 13.9 4.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) CTI PF06934.11 KFO98231.1 - 0.064 11.8 0.2 0.076 11.5 0.2 1.1 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) MRPL52 PF18699.1 KFO98231.1 - 2.5 8.3 9.6 0.82 9.9 3.9 2.2 1 1 1 2 2 2 0 Mitoribosomal protein mL52 Histone_HNS PF00816.21 KFO98231.1 - 3.4 8.5 6.6 0.57 11.0 2.9 1.7 2 0 0 2 2 2 0 H-NS histone family FlxA PF14282.6 KFO98231.1 - 4.1 7.4 10.4 0.26 11.3 4.4 1.9 3 0 0 3 3 3 0 FlxA-like protein OST-HTH PF12872.7 KFO98232.1 - 1.1e-68 227.0 0.6 2e-12 46.7 0.0 8.4 8 0 0 8 8 8 6 OST-HTH/LOTUS domain Limkain-b1 PF11608.8 KFO98232.1 - 3.6e-39 132.7 0.3 9e-39 131.4 0.3 1.7 1 0 0 1 1 1 1 Limkain b1 NYN PF01936.18 KFO98232.1 - 7.1e-19 68.7 0.0 1.7e-18 67.5 0.0 1.7 1 0 0 1 1 1 1 NYN domain RRM_1 PF00076.22 KFO98232.1 - 4.6e-08 32.8 0.0 5.7e-05 22.9 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFO98232.1 - 0.00057 19.5 0.1 0.17 11.5 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NUDE_C PF04880.13 KFO98233.1 - 4.2e-44 151.1 4.3 4.2e-44 151.1 4.3 2.4 2 0 0 2 2 2 1 NUDE protein, C-terminal conserved region DMPK_coil PF08826.10 KFO98233.1 - 0.0027 17.8 8.0 0.0027 17.8 8.0 3.8 2 1 1 3 3 3 1 DMPK coiled coil domain like TPR_MLP1_2 PF07926.12 KFO98233.1 - 0.0052 16.8 33.5 0.053 13.6 9.1 3.2 2 1 1 3 3 3 2 TPR/MLP1/MLP2-like protein PRKG1_interact PF15898.5 KFO98233.1 - 0.0081 17.0 10.5 0.0081 17.0 10.5 3.4 1 1 2 3 3 3 2 cGMP-dependent protein kinase interacting domain HIP1_clath_bdg PF16515.5 KFO98233.1 - 0.015 15.9 11.4 0.015 15.9 11.4 3.1 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 YabA PF06156.13 KFO98233.1 - 0.16 12.6 24.9 3.1 8.5 5.5 3.5 1 1 2 3 3 3 0 Initiation control protein YabA ATG16 PF08614.11 KFO98233.1 - 0.21 11.8 39.0 0.5 10.6 22.5 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF5082 PF16888.5 KFO98233.1 - 1.4 9.2 20.1 1.3 9.3 10.3 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) FPP PF05911.11 KFO98233.1 - 1.7 6.8 30.0 2 6.5 10.1 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil ADIP PF11559.8 KFO98233.1 - 2.3 8.3 31.9 0.63 10.1 7.6 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF2514 PF10721.9 KFO98233.1 - 3.3 7.7 11.0 0.4 10.7 4.6 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2514) DUF148 PF02520.17 KFO98233.1 - 3.6 7.7 15.9 0.081 13.0 4.0 2.6 1 1 0 2 2 2 0 Domain of unknown function DUF148 PspA_IM30 PF04012.12 KFO98233.1 - 5.3 6.5 30.1 1.3 8.5 6.2 3.0 1 1 2 3 3 3 0 PspA/IM30 family Titin_Ig-rpts PF06582.12 KFO98233.1 - 5.6 7.0 9.5 0.6 10.1 0.9 3.4 3 0 0 3 3 3 0 Titin repeat GAS PF13851.6 KFO98233.1 - 8.2 5.7 34.0 0.74 9.1 20.1 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 KFO98233.1 - 8.7 6.4 12.1 1.8 8.6 4.7 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 KFO98233.1 - 9.5 6.6 30.8 0.29 11.5 12.3 2.3 1 1 1 2 2 2 0 Fez1 FOP_dimer PF09398.10 KFO98234.1 - 1.6e-22 79.5 0.1 2.7e-22 78.8 0.1 1.3 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 KFO98234.1 - 3.6e-06 25.9 0.3 6.6e-06 25.0 0.2 1.5 1 1 0 1 1 1 1 LisH ABC_membrane PF00664.23 KFO98235.1 - 6.6e-94 314.6 31.0 2.4e-51 175.0 6.8 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFO98235.1 - 1.9e-54 183.9 0.0 4.7e-29 101.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFO98235.1 - 2e-09 37.2 1.1 0.00055 19.4 0.0 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KFO98235.1 - 7.2e-06 26.1 0.6 0.072 13.2 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KFO98235.1 - 1.1e-05 25.9 0.0 0.0016 18.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFO98235.1 - 1.8e-05 24.7 0.5 0.0056 16.6 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase Zeta_toxin PF06414.12 KFO98235.1 - 0.00066 19.0 1.4 0.0029 16.9 0.1 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.6 KFO98235.1 - 0.00079 19.1 0.3 0.058 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KFO98235.1 - 0.0038 17.3 2.6 0.028 14.5 0.2 2.7 2 0 0 2 2 2 1 Dynamin family AAA_21 PF13304.6 KFO98235.1 - 0.0041 17.0 1.2 3.2 7.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 KFO98235.1 - 0.0043 15.9 0.0 0.26 10.1 0.0 2.9 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_7 PF12775.7 KFO98235.1 - 0.011 15.2 0.2 0.43 10.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 KFO98235.1 - 0.015 15.0 2.3 2.7 7.8 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KFO98235.1 - 0.021 15.3 2.5 4.4 7.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 KFO98235.1 - 0.031 13.9 0.0 2.6 7.7 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.6 KFO98235.1 - 0.038 14.3 2.9 1.9 8.7 0.1 3.2 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 KFO98235.1 - 0.058 13.6 0.8 23 5.2 0.0 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 KFO98235.1 - 0.068 13.2 2.6 4.7 7.2 0.2 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain DUF815 PF05673.13 KFO98235.1 - 0.097 11.8 0.3 3.1 6.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.9 KFO98235.1 - 0.14 11.1 0.9 8.3 5.2 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 KFO98235.1 - 0.18 11.5 1.1 11 5.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 KFO98235.1 - 0.19 10.9 2.1 11 5.1 0.1 2.6 2 1 0 2 2 2 0 NB-ARC domain cobW PF02492.19 KFO98235.1 - 0.25 10.9 0.7 2 7.9 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_membrane PF00664.23 KFO98236.1 - 2.1e-62 211.2 27.9 3.6e-34 118.7 18.0 2.7 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFO98236.1 - 3.3e-53 179.9 0.2 4.7e-30 104.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFO98236.1 - 6.8e-11 42.0 0.0 3.5e-05 23.4 0.0 3.6 1 1 2 3 3 3 3 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 KFO98236.1 - 2.6e-06 26.8 0.3 0.0023 17.2 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.6 KFO98236.1 - 4.1e-06 27.1 2.1 0.052 13.8 0.4 3.3 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KFO98236.1 - 8.6e-06 26.2 2.0 0.014 15.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KFO98236.1 - 1.1e-05 25.5 0.1 0.049 13.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFO98236.1 - 1.4e-05 25.1 0.1 0.0074 16.2 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KFO98236.1 - 5.8e-05 22.8 0.6 0.24 11.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 KFO98236.1 - 0.00015 21.4 1.3 0.015 14.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KFO98236.1 - 0.00019 20.6 0.5 0.35 9.9 0.1 2.7 2 1 0 2 2 2 2 Type II/IV secretion system protein Dynamin_N PF00350.23 KFO98236.1 - 0.0002 21.4 1.1 0.0069 16.5 0.0 3.3 3 0 0 3 3 3 1 Dynamin family AAA_23 PF13476.6 KFO98236.1 - 0.0055 17.2 0.2 2.6 8.5 0.2 2.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KFO98236.1 - 0.0083 16.0 2.3 3.6 7.3 0.1 3.9 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system MeaB PF03308.16 KFO98236.1 - 0.039 12.9 0.5 1.8 7.5 0.1 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KFO98236.1 - 0.042 13.6 1.9 6.6 6.4 0.1 2.9 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KFO98236.1 - 0.055 13.0 0.1 3.3 7.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 KFO98236.1 - 0.065 13.8 0.0 1.4 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 KFO98236.1 - 0.077 11.8 0.9 3 6.5 0.1 2.9 3 0 0 3 3 3 0 Predicted ATPase of the ABC class TsaE PF02367.17 KFO98236.1 - 0.11 12.5 0.8 20 5.2 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.17 KFO98236.1 - 0.12 12.5 8.5 0.43 10.6 0.2 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 KFO98236.1 - 0.12 11.2 2.1 1.3 7.9 0.4 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 KFO98236.1 - 0.16 11.5 3.6 3.4 7.2 0.3 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 KFO98236.1 - 0.17 11.6 1.4 1.4 8.6 0.0 2.6 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_33 PF13671.6 KFO98236.1 - 0.23 11.6 0.6 20 5.3 0.2 2.7 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KFO98236.1 - 0.28 11.1 1.5 3.5 7.5 0.2 2.4 2 0 0 2 2 2 0 NTPase APS_kinase PF01583.20 KFO98236.1 - 0.42 10.5 2.6 0.76 9.7 0.2 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF2075 PF09848.9 KFO98236.1 - 0.54 9.4 1.8 13 4.9 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 KFO98236.1 - 1.5 8.7 10.2 17 5.3 0.3 3.9 4 0 0 4 4 4 0 NACHT domain NB-ARC PF00931.22 KFO98236.1 - 1.9 7.6 5.2 15 4.7 0.1 3.3 3 1 0 3 3 3 0 NB-ARC domain Wzy_C_2 PF11846.8 KFO98236.1 - 7.4 6.4 8.7 0.27 11.1 0.8 2.5 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal CarboxypepD_reg PF13620.6 KFO98237.1 - 8.9e-45 150.9 6.5 5.7e-08 32.9 0.5 9.4 9 1 0 9 9 9 7 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 KFO98237.1 - 9.9e-27 93.4 5.4 0.00014 22.0 0.1 9.3 9 0 0 9 9 9 6 SdrD B-like domain DUF2012 PF09430.10 KFO98237.1 - 1e-22 80.5 0.4 2.2e-07 31.0 0.0 7.5 7 1 1 8 8 8 4 Protein of unknown function (DUF2012) CarbopepD_reg_2 PF13715.6 KFO98237.1 - 1.5e-17 63.4 7.2 4.4e-05 23.4 0.7 8.4 8 0 0 8 8 8 5 CarboxypepD_reg-like domain SpaA PF17802.1 KFO98237.1 - 7.9e-15 55.0 4.7 0.0013 19.0 0.0 6.8 7 0 0 7 7 7 3 Prealbumin-like fold domain fn3_3 PF14686.6 KFO98237.1 - 7.5e-12 44.9 0.2 0.0021 17.8 0.0 7.0 8 0 0 8 8 8 2 Polysaccharide lyase family 4, domain II DUF2846 PF11008.8 KFO98237.1 - 6.5e-05 22.9 0.3 13 5.9 0.0 5.2 6 0 0 6 6 6 1 Protein of unknown function (DUF2846) Dioxygenase_C PF00775.21 KFO98237.1 - 0.00021 20.8 0.0 12 5.2 0.0 5.0 5 0 0 5 5 5 1 Dioxygenase Y_Y_Y PF07495.13 KFO98237.1 - 0.00038 20.4 2.2 1.3 9.1 0.0 4.5 5 0 0 5 5 5 1 Y_Y_Y domain TTR-52 PF01060.23 KFO98237.1 - 0.0041 17.8 0.1 21 5.9 0.0 4.8 5 0 0 5 5 5 0 Transthyretin-like family Cupredoxin_1 PF13473.6 KFO98237.1 - 0.073 13.2 0.1 3 8.0 0.0 3.5 2 1 1 3 3 3 0 Cupredoxin-like domain KH_1 PF00013.29 KFO98238.1 - 1.1e-21 76.4 0.8 3.6e-14 52.3 0.1 2.3 2 0 0 2 2 2 2 KH domain zf-C3HC4_3 PF13920.6 KFO98238.1 - 1.1e-11 44.3 11.4 1.7e-11 43.8 11.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFO98238.1 - 2.3e-06 27.3 11.4 3.9e-06 26.6 11.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFO98238.1 - 5.8e-05 22.9 13.1 9.5e-05 22.2 13.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFO98238.1 - 0.019 15.0 5.5 0.019 15.0 5.5 1.9 1 1 1 2 2 2 0 RING-type zinc-finger zf-C2HC5 PF06221.13 KFO98238.1 - 0.019 14.9 6.1 0.042 13.8 6.1 1.6 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zf-RING_5 PF14634.6 KFO98238.1 - 0.05 13.6 11.1 0.092 12.7 11.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain KH_2 PF07650.17 KFO98238.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 KH domain zf-RING_4 PF14570.6 KFO98238.1 - 0.4 10.5 8.9 0.82 9.5 8.9 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Pkinase PF00069.25 KFO98239.1 - 0.001 18.5 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Yae1_N PF09811.9 KFO98240.1 - 1.2e-10 40.8 32.2 91 2.9 32.2 3.2 1 1 0 1 1 1 1 Essential protein Yae1, N terminal Sortilin-Vps10 PF15902.5 KFO98241.1 - 5.6e-106 355.0 1.0 2.4e-105 352.9 0.2 1.9 2 0 0 2 2 2 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KFO98241.1 - 5.4e-36 124.5 4.0 8.7e-36 123.8 4.0 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal PKD PF00801.20 KFO98241.1 - 4.4e-16 58.5 1.1 1.5e-09 37.6 0.0 2.5 2 0 0 2 2 2 2 PKD domain BNR PF02012.20 KFO98241.1 - 0.0023 17.7 16.8 0.54 10.5 0.6 6.6 6 0 0 6 6 6 2 BNR/Asp-box repeat Mab-21 PF03281.14 KFO98243.1 - 5.9e-23 81.6 1.0 2.3e-21 76.4 1.0 2.3 1 1 0 1 1 1 1 Mab-21 protein CemA PF03040.14 KFO98243.1 - 0.079 12.9 0.6 0.14 12.0 0.6 1.3 1 0 0 1 1 1 0 CemA family DUF4795 PF16043.5 KFO98243.1 - 3.7 7.1 8.4 0.21 11.2 2.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) GST_N_3 PF13417.6 KFO98244.1 - 2.4e-21 75.9 0.0 5.2e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFO98244.1 - 1.2e-15 57.6 0.0 2.3e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFO98244.1 - 1e-12 48.2 0.0 1.8e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFO98244.1 - 1.7e-08 34.6 0.1 2.8e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFO98244.1 - 3.5e-07 30.1 0.0 7.3e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFO98244.1 - 8.3e-07 29.1 0.1 1.3e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KFO98244.1 - 0.00061 20.0 0.0 0.0019 18.4 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin GST_C_5 PF16865.5 KFO98244.1 - 0.0059 17.2 0.0 0.0093 16.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KFO98244.1 - 0.012 16.3 0.0 0.028 15.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Mei5 PF10376.9 KFO98247.1 - 3.9e-57 193.5 2.5 4.4e-57 193.3 2.5 1.0 1 0 0 1 1 1 1 Double-strand recombination repair protein Mei5_like PF17021.5 KFO98247.1 - 0.0032 17.5 0.2 0.0056 16.7 0.2 1.4 1 0 0 1 1 1 1 Putative double-strand recombination repair-like DUF4868 PF16162.5 KFO98247.1 - 0.014 15.3 0.4 0.026 14.5 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4868) Collagen PF01391.18 KFO98248.1 - 3.7e-63 209.1 375.3 1.9e-09 37.1 33.5 17.3 10 4 5 15 15 15 14 Collagen triple helix repeat (20 copies) DUF2868 PF11067.8 KFO98248.1 - 3.2 7.2 5.9 6 6.3 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) PKK PF12474.8 KFO98249.1 - 7.7e-78 259.4 101.4 2.1e-41 141.3 43.1 8.0 8 1 1 9 9 9 2 Polo kinase kinase Pkinase PF00069.25 KFO98249.1 - 5.2e-68 229.3 0.0 5.2e-68 229.3 0.0 3.6 3 1 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO98249.1 - 9e-48 162.8 0.0 9e-48 162.8 0.0 3.3 4 0 0 4 4 4 1 Protein tyrosine kinase APH PF01636.23 KFO98249.1 - 1.2 9.0 0.0 1.2 9.0 0.0 3.7 3 1 0 3 3 3 0 Phosphotransferase enzyme family STN1_2 PF09170.10 KFO98250.1 - 5.6e-64 215.6 5.6 2.5e-63 213.5 5.6 2.0 1 1 0 1 1 1 1 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 tRNA_anti-codon PF01336.25 KFO98250.1 - 2.3e-08 33.9 0.1 4.8e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Stn1 PF10451.9 KFO98250.1 - 3.6e-07 29.4 0.1 2.1e-06 26.9 0.1 2.1 1 1 0 2 2 2 1 Telomere regulation protein Stn1 DUF4364 PF14277.6 KFO98250.1 - 0.029 14.1 0.0 0.075 12.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) PX PF00787.24 KFO98251.1 - 9.2e-17 61.1 0.1 1e-16 60.9 0.1 1.0 1 0 0 1 1 1 1 PX domain SH3_1 PF00018.28 KFO98252.1 - 9.3e-39 130.8 20.1 4.4e-11 42.2 0.3 5.4 5 0 0 5 5 5 5 SH3 domain SH3_2 PF07653.17 KFO98252.1 - 3e-35 119.7 8.2 2e-10 40.2 0.1 5.4 5 0 0 5 5 5 5 Variant SH3 domain SH3_9 PF14604.6 KFO98252.1 - 8.9e-33 111.9 14.5 4.9e-10 39.1 0.1 5.4 5 0 0 5 5 5 5 Variant SH3 domain SH3_3 PF08239.11 KFO98252.1 - 1e-15 57.7 22.5 0.00078 19.7 0.1 5.6 5 0 0 5 5 5 5 Bacterial SH3 domain DUF1604 PF07713.13 KFO98252.1 - 0.0054 16.5 10.8 0.94 9.3 0.1 5.5 5 0 0 5 5 5 1 Protein of unknown function (DUF1604) hSH3 PF14603.6 KFO98252.1 - 0.065 13.7 0.2 3.1 8.3 0.0 3.2 3 0 0 3 3 3 0 Helically-extended SH3 domain SH3_6 PF12913.7 KFO98252.1 - 0.34 10.5 3.4 1.7 8.3 0.1 2.9 2 0 0 2 2 2 0 SH3 domain (SH3b1 type) Neuralized PF07177.12 KFO98253.1 - 5e-83 276.5 0.0 2.2e-40 138.1 0.0 2.1 2 0 0 2 2 2 2 Neuralized zf-C3HC4_3 PF13920.6 KFO98253.1 - 4.3e-13 48.9 13.1 4.3e-13 48.9 13.1 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFO98253.1 - 8.8e-06 25.5 11.7 8.8e-06 25.5 11.7 3.2 4 0 0 4 4 4 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFO98253.1 - 0.41 10.6 21.7 0.028 14.4 14.7 2.7 3 0 0 3 3 3 0 zinc-RING finger domain Ca_hom_mod PF14798.6 KFO98254.1 - 3.7e-96 321.1 9.8 4.3e-96 320.9 9.8 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator Ca_hom_mod PF14798.6 KFO98255.1 - 1.9e-93 312.2 6.0 2.2e-93 312.0 6.0 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator Ca_hom_mod PF14798.6 KFO98256.1 - 2.4e-86 289.0 0.8 2.8e-86 288.7 0.8 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator DUF1218 PF06749.12 KFO98256.1 - 0.0052 17.3 2.2 0.02 15.4 0.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1218) DUF996 PF06195.13 KFO98256.1 - 0.043 14.1 0.3 0.41 10.9 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF996) Suf PF05843.14 KFO98257.1 - 1e-12 48.7 5.0 2.5e-08 34.2 1.1 4.4 2 2 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KFO98257.1 - 5.2e-09 36.5 0.1 0.0029 18.1 0.0 3.9 2 1 1 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFO98257.1 - 3.7e-08 33.5 7.5 0.021 15.6 0.4 5.2 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 KFO98257.1 - 4.4e-07 29.4 5.8 0.0029 16.9 0.5 3.2 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFO98257.1 - 0.0029 17.8 3.5 0.013 15.7 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFO98257.1 - 0.0052 17.4 0.2 3 8.5 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat PVL_ORF50 PF07768.11 KFO98257.1 - 8.8 6.7 18.1 0.084 13.2 4.2 3.3 3 0 0 3 3 3 0 PVL ORF-50-like family ATP_synth_reg PF14960.6 KFO98258.1 - 8e-27 92.5 0.1 9e-27 92.3 0.1 1.0 1 0 0 1 1 1 1 ATP synthase regulation WD40 PF00400.32 KFO98259.1 - 6.4e-58 191.4 9.9 3.1e-11 43.6 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KFO98259.1 - 5.9e-43 146.2 4.6 1.2e-42 145.2 4.6 1.5 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KFO98259.1 - 3.1e-15 56.2 0.0 0.00067 19.9 0.0 5.4 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFO98259.1 - 4.2e-09 35.6 0.6 0.0028 16.4 0.0 3.7 4 0 0 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFO98259.1 - 2.8e-06 26.5 0.0 2.3 7.1 0.0 4.1 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFO98259.1 - 0.003 16.9 0.0 0.81 9.0 0.0 3.5 3 1 1 4 4 4 1 WD40-like domain RAB3GAP2_N PF14655.6 KFO98259.1 - 0.012 15.0 0.0 0.12 11.6 0.0 2.3 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Cytochrom_D1 PF02239.16 KFO98259.1 - 0.037 12.6 0.0 1.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.12 KFO98259.1 - 0.1 12.6 0.1 31 4.6 0.1 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat VID27 PF08553.10 KFO98259.1 - 0.12 11.3 0.3 0.48 9.4 0.0 1.8 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain zf-C3HC4_2 PF13923.6 KFO98260.1 - 2.6e-10 40.0 9.1 5.2e-10 39.0 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFO98260.1 - 1.3e-08 34.5 11.0 2.3e-08 33.7 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RAWUL PF16207.5 KFO98260.1 - 1.1e-06 29.2 0.0 2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-RING_UBOX PF13445.6 KFO98260.1 - 1.8e-06 27.9 7.7 3.8e-06 26.8 7.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFO98260.1 - 1.8e-05 24.9 9.8 1.8e-05 24.9 9.8 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFO98260.1 - 8.5e-05 22.3 8.7 0.00015 21.5 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFO98260.1 - 0.00022 21.1 10.7 0.00047 20.0 10.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 KFO98260.1 - 0.0021 17.9 2.6 0.0036 17.1 2.6 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KFO98260.1 - 0.0048 17.0 5.9 0.022 14.9 4.4 2.2 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 KFO98260.1 - 0.01 16.0 10.4 0.021 15.0 10.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFO98260.1 - 0.11 12.4 8.4 0.21 11.5 8.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFO98260.1 - 0.23 11.8 9.6 0.76 10.1 9.6 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-Nse PF11789.8 KFO98260.1 - 0.31 10.9 5.4 0.55 10.1 5.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TackOD1 PF18551.1 KFO98260.1 - 0.49 10.0 9.9 0.18 11.5 2.4 2.5 2 1 1 3 3 3 0 Thaumarchaeal output domain 1 DUF1272 PF06906.11 KFO98260.1 - 1 9.5 6.1 2.5 8.3 6.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_5 PF17121.5 KFO98260.1 - 1.4 8.8 9.0 4.1 7.4 9.0 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) 5_nucleotid PF05761.14 KFO98261.1 - 1.4e-176 588.0 0.0 1.7e-176 587.6 0.0 1.1 1 0 0 1 1 1 1 5' nucleotidase family Methyltransf_31 PF13847.6 KFO98262.1 - 1.4e-33 115.8 0.0 2.6e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFO98262.1 - 1.1e-20 74.1 0.0 3.1e-20 72.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFO98262.1 - 2.3e-19 69.9 0.0 4.6e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFO98262.1 - 2.2e-15 56.6 0.0 3.5e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KFO98262.1 - 2.8e-14 53.3 0.0 5.1e-14 52.4 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFO98262.1 - 6.5e-13 49.3 0.0 1.3e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFO98262.1 - 4.1e-06 26.7 0.0 6.1e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.15 KFO98262.1 - 5.7e-05 23.1 0.0 0.0001 22.3 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase PrmA PF06325.13 KFO98262.1 - 9.3e-05 22.0 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KFO98262.1 - 0.00036 20.1 0.0 0.00072 19.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 KFO98262.1 - 0.00039 19.9 0.0 0.00093 18.7 0.0 1.6 2 0 0 2 2 2 1 Tellurite resistance protein TehB MetW PF07021.12 KFO98262.1 - 0.062 12.9 0.5 0.6 9.7 0.5 2.1 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KFO98262.1 - 0.08 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 KFO98262.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.5 1 1 0 1 1 1 0 Lysine methyltransferase Methyltransf_5 PF01795.19 KFO98262.1 - 0.17 11.3 0.0 0.36 10.3 0.0 1.5 1 0 0 1 1 1 0 MraW methylase family Peptidase_M29 PF02073.15 KFO98262.1 - 0.22 10.3 0.1 0.34 9.7 0.1 1.2 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) BORCS7 PF16088.5 KFO98263.1 - 6.1e-35 119.6 1.8 6.8e-35 119.4 1.8 1.0 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 7 p450 PF00067.22 KFO98264.1 - 1.4e-141 472.4 0.0 1.6e-141 472.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WBP-1 PF11669.8 KFO98265.1 - 6.6e-45 152.0 12.9 1.3e-44 151.1 12.9 1.5 1 0 0 1 1 1 1 WW domain-binding protein 1 TMIE PF16038.5 KFO98265.1 - 0.015 15.1 0.6 0.026 14.3 0.6 1.3 1 0 0 1 1 1 0 TMIE protein Mtc PF03820.17 KFO98266.1 - 4.3e-112 374.2 0.3 5.1e-112 373.9 0.3 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Arf PF00025.21 KFO98267.1 - 4.3e-72 241.2 0.0 4.9e-72 241.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFO98267.1 - 1.8e-14 53.6 0.0 2e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KFO98267.1 - 1.8e-14 53.9 0.0 2.5e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KFO98267.1 - 1.9e-14 53.6 0.5 1.4e-08 34.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KFO98267.1 - 1.7e-13 50.5 0.0 2e-13 50.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KFO98267.1 - 1e-12 47.9 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFO98267.1 - 1.2e-08 35.0 0.0 1.7e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFO98267.1 - 4.8e-05 23.0 0.0 0.0031 17.1 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 KFO98267.1 - 0.00018 22.0 0.0 0.00025 21.5 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 KFO98267.1 - 0.0068 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 KFO98267.1 - 0.01 16.4 0.0 0.017 15.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFO98267.1 - 0.014 15.3 0.1 5.3 6.9 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_14 PF13173.6 KFO98267.1 - 0.024 14.7 0.1 0.047 13.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KFO98267.1 - 0.046 13.6 0.0 7.4 6.5 0.0 2.2 2 0 0 2 2 2 0 NACHT domain FeoB_N PF02421.18 KFO98267.1 - 0.052 13.1 0.1 0.17 11.4 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B cobW PF02492.19 KFO98267.1 - 0.061 12.9 0.1 7.8 6.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KFO98267.1 - 0.072 12.1 0.0 2.8 6.8 0.0 2.5 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KFO98267.1 - 0.1 12.8 0.1 0.81 10.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 KFO98267.1 - 0.15 12.1 0.0 4 7.5 0.0 2.1 1 1 1 2 2 2 0 Dynamin family zf-C3HC4_4 PF15227.6 KFO98268.1 - 1.1e-10 41.4 8.1 1.1e-10 41.4 8.1 3.4 4 0 0 4 4 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KFO98268.1 - 1.5e-09 37.6 6.5 1.5e-09 37.6 6.5 2.8 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFO98268.1 - 6e-09 35.8 8.1 6e-09 35.8 8.1 2.6 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFO98268.1 - 6.2e-08 32.3 7.8 2.8e-07 30.3 7.8 2.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFO98268.1 - 8e-06 26.1 8.3 8e-06 26.1 8.3 3.3 3 1 0 3 3 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFO98268.1 - 2.7e-05 23.9 6.0 2.7e-05 23.9 6.0 3.4 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 KFO98268.1 - 0.00011 22.2 7.5 0.00011 22.2 7.5 5.4 5 1 0 5 5 4 1 B-box zinc finger zf-RING_10 PF16685.5 KFO98268.1 - 0.0023 18.0 3.9 0.0023 18.0 3.9 3.3 4 1 0 4 4 1 1 zinc RING finger of MSL2 zf-RING_5 PF14634.6 KFO98268.1 - 0.013 15.5 8.3 0.013 15.5 8.3 4.0 3 2 0 3 3 2 0 zinc-RING finger domain zf-Nse PF11789.8 KFO98268.1 - 0.02 14.7 4.1 0.06 13.2 4.1 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 KFO98268.1 - 0.11 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 U-box domain DUF3552 PF12072.8 KFO98268.1 - 0.39 10.1 14.1 0.7 9.3 14.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) dCache_2 PF08269.11 KFO98268.1 - 0.9 8.7 4.5 1.4 8.0 4.5 1.3 1 0 0 1 1 1 0 Cache domain Zn_ribbon_recom PF13408.6 KFO98268.1 - 0.91 10.1 6.5 1 9.9 0.0 3.6 2 1 0 2 2 1 0 Recombinase zinc beta ribbon domain Exonuc_VII_L PF02601.15 KFO98268.1 - 0.92 9.0 4.6 1.3 8.5 4.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phasin PF05597.11 KFO98268.1 - 1.1 9.3 8.4 1.9 8.5 8.4 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) CASP_C PF08172.12 KFO98268.1 - 1.5 8.1 10.4 1 8.7 8.2 1.6 1 1 0 1 1 1 0 CASP C terminal DUF1461 PF07314.11 KFO98268.1 - 1.7 8.5 2.9 2.9 7.8 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) DUF3287 PF11690.8 KFO98268.1 - 2 8.2 5.5 2.5 7.8 4.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) OEP PF02321.18 KFO98268.1 - 3 7.6 8.7 4.7 7.0 8.7 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein zf-RING_6 PF14835.6 KFO98268.1 - 4.3 7.3 10.9 0.074 12.9 3.0 2.2 2 0 0 2 2 1 0 zf-RING of BARD1-type protein SUFU_C PF12470.8 KFO98269.1 - 3.9e-83 278.5 0.0 5.2e-83 278.1 0.0 1.2 1 0 0 1 1 1 1 Suppressor of Fused Gli/Ci N terminal binding domain SUFU PF05076.13 KFO98269.1 - 4.1e-51 173.4 0.0 6e-51 172.8 0.0 1.2 1 0 0 1 1 1 1 Suppressor of fused protein (SUFU) Actin PF00022.19 KFO98270.1 - 1.9e-126 422.0 0.0 8.5e-126 419.8 0.0 1.8 1 1 0 1 1 1 1 Actin MFS_2 PF13347.6 KFO98271.1 - 8.4e-22 77.3 18.8 1.3e-19 70.1 18.8 2.8 1 1 0 1 1 1 1 MFS/sugar transport protein FAM178 PF14816.6 KFO98274.1 - 3.4e-147 490.3 8.1 4.8e-147 489.8 8.1 1.2 1 0 0 1 1 1 1 Family of unknown function, FAM178 TerB_C PF15615.6 KFO98274.1 - 0.028 14.7 1.7 0.069 13.5 1.7 1.7 1 0 0 1 1 1 0 TerB-C domain Sema PF01403.19 KFO98275.1 - 3.4e-148 494.0 0.0 4.6e-148 493.5 0.0 1.2 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 KFO98275.1 - 4.7e-05 23.8 5.5 0.00019 21.9 5.5 2.1 1 0 0 1 1 1 1 Plexin repeat Ig_3 PF13927.6 KFO98275.1 - 0.005 17.4 0.0 0.018 15.6 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFO98275.1 - 0.0056 17.0 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFO98275.1 - 0.017 15.3 0.0 0.043 14.0 0.0 1.7 2 0 0 2 2 2 0 Immunoglobulin domain PSI_integrin PF17205.3 KFO98275.1 - 0.068 12.9 1.2 0.19 11.5 1.2 1.8 1 0 0 1 1 1 0 Integrin plexin domain L51_S25_CI-B8 PF05047.16 KFO98276.1 - 6.9e-08 32.3 0.0 2e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain AAA_25 PF13481.6 KFO98277.1 - 9.5e-13 48.2 0.0 1.6e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFO98277.1 - 1.3e-05 25.6 0.0 2.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 KFO98277.1 - 2e-05 24.1 0.0 2.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain T2SSE PF00437.20 KFO98277.1 - 0.00013 21.1 0.0 0.00017 20.8 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 KFO98277.1 - 0.00032 20.4 0.0 0.00074 19.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KFO98277.1 - 0.0005 20.6 0.0 0.00073 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KFO98277.1 - 0.0033 16.8 0.0 0.0049 16.2 0.0 1.2 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.6 KFO98277.1 - 0.008 16.5 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFO98277.1 - 0.02 15.0 0.0 0.044 13.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFO98277.1 - 0.025 14.3 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFO98277.1 - 0.041 14.4 0.1 0.071 13.6 0.1 1.4 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 KFO98277.1 - 0.044 14.1 0.0 0.077 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KFO98277.1 - 0.047 13.7 0.0 0.082 12.9 0.0 1.5 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 KFO98277.1 - 0.052 13.0 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein cobW PF02492.19 KFO98277.1 - 0.057 13.0 0.1 0.09 12.4 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KFO98277.1 - 0.067 12.7 0.0 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KFO98277.1 - 0.072 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 KFO98277.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_21 PF13304.6 KFO98277.1 - 0.14 11.9 0.5 0.44 10.3 0.2 1.9 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ATPase_2 PF01637.18 KFO98277.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PDZ PF00595.24 KFO98278.1 - 4.6e-12 46.1 0.1 4.7e-12 46.1 0.1 1.0 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFO98278.1 - 1e-05 25.2 0.3 4.2e-05 23.3 0.3 1.8 1 1 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFO98279.1 - 3.5e-36 123.4 1.2 1.8e-17 63.5 0.3 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFO98279.1 - 3.9e-22 77.8 0.4 7.1e-11 41.8 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFO98279.1 - 5.6e-13 49.0 0.2 3.7e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 KFO98279.1 - 0.0068 16.3 0.5 1.6 8.7 0.0 2.5 2 0 0 2 2 2 2 Tricorn protease PDZ domain Mtc PF03820.17 KFO98280.1 - 6.6e-152 505.0 0.1 7.5e-152 504.8 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier GDC-P PF02347.16 KFO98280.1 - 0.11 11.3 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein I-set PF07679.16 KFO98281.1 - 2.2e-13 50.1 0.0 3.1e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO98281.1 - 3.1e-13 50.1 0.0 4.7e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain IGFBP PF00219.18 KFO98281.1 - 7.3e-09 36.1 19.6 7.3e-09 36.1 19.6 2.3 2 0 0 2 2 2 1 Insulin-like growth factor binding protein Ig_2 PF13895.6 KFO98281.1 - 8.9e-06 26.0 0.0 2.1e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Kazal_2 PF07648.15 KFO98281.1 - 1.1e-05 25.5 10.8 0.00011 22.2 0.4 2.6 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain ig PF00047.25 KFO98281.1 - 1.7e-05 24.9 0.0 3.7e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain Kazal_1 PF00050.21 KFO98281.1 - 7e-05 22.8 0.2 7e-05 22.8 0.2 2.4 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain V-set PF07686.17 KFO98281.1 - 0.0016 18.6 0.0 0.0053 16.9 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin V-set domain Homeodomain PF00046.29 KFO98282.1 - 8.1e-23 80.0 2.9 1.2e-22 79.4 2.9 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO98282.1 - 7.4e-05 22.6 0.4 0.00016 21.5 0.2 1.7 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.8 KFO98282.1 - 0.0034 16.8 0.1 0.0047 16.4 0.1 1.3 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez WD40 PF00400.32 KFO98283.1 - 9.8e-40 133.8 18.6 2.3e-06 28.2 0.2 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Beta-TrCP_D PF12125.8 KFO98283.1 - 3.7e-24 84.3 4.0 7.3e-24 83.4 4.0 1.5 1 0 0 1 1 1 1 D domain of beta-TrCP F-box-like PF12937.7 KFO98283.1 - 1.7e-10 40.6 0.5 5e-10 39.1 0.2 2.0 1 1 1 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 KFO98283.1 - 2.7e-09 37.2 2.1 0.06 13.7 0.0 4.4 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 KFO98283.1 - 6.7e-07 29.0 0.0 1.8e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 KFO98283.1 - 5.6e-06 25.9 0.3 0.0038 16.6 0.1 2.4 1 1 1 2 2 2 2 WD40-like domain Nup160 PF11715.8 KFO98283.1 - 6.5e-05 21.8 6.8 0.094 11.3 0.2 4.6 3 1 2 5 5 5 2 Nucleoporin Nup120/160 F-box_5 PF18511.1 KFO98283.1 - 0.0062 16.1 0.1 0.019 14.6 0.1 1.9 1 0 0 1 1 1 1 F-box eIF2A PF08662.11 KFO98283.1 - 0.039 13.8 0.0 4.4 7.1 0.0 2.5 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF4508 PF14969.6 KFO98283.1 - 0.065 13.5 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) DUF5046 PF16465.5 KFO98283.1 - 0.072 12.5 0.2 5.5 6.3 0.1 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF5046) 120_Rick_ant PF12574.8 KFO98283.1 - 0.12 11.5 0.1 0.58 9.3 0.0 1.9 1 1 1 2 2 2 0 120 KDa Rickettsia surface antigen Sugar_tr PF00083.24 KFO98284.1 - 9.6e-106 354.3 21.7 1.1e-105 354.2 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFO98284.1 - 1.3e-16 60.5 35.6 1.9e-12 46.8 11.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BChl_A PF02327.17 KFO98284.1 - 0.07 11.9 0.0 0.098 11.4 0.0 1.1 1 0 0 1 1 1 0 Bacteriochlorophyll A protein DNA_pol_B_palm PF14792.6 KFO98285.1 - 1.5e-35 121.8 0.0 4.1e-35 120.4 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 KFO98285.1 - 5e-22 77.8 0.0 1.3e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 KFO98285.1 - 3.2e-21 74.9 0.1 4.5e-20 71.2 0.2 2.4 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 KFO98285.1 - 5.4e-19 68.3 0.1 1.2e-18 67.2 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 KFO98285.1 - 1.3e-05 25.7 0.0 0.12 13.0 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix domain HHH PF00633.23 KFO98285.1 - 0.028 14.3 0.0 0.067 13.1 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Cdd1 PF11731.8 KFO98285.1 - 0.054 13.7 0.0 11 6.4 0.0 2.6 2 0 0 2 2 2 0 Pathogenicity locus NTP_transf_2 PF01909.23 KFO98285.1 - 0.061 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain IMS_HHH PF11798.8 KFO98285.1 - 0.11 12.9 0.2 0.33 11.4 0.1 1.9 2 0 0 2 2 2 0 IMS family HHH motif DPCD PF14913.6 KFO98286.1 - 2.4e-91 304.3 0.6 2.7e-91 304.1 0.6 1.0 1 0 0 1 1 1 1 DPCD protein family Mcl1_mid PF12341.8 KFO98286.1 - 0.036 13.4 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region FGF PF00167.18 KFO98287.1 - 1.1e-42 145.1 1.0 1.6e-42 144.6 1.0 1.2 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.13 KFO98287.1 - 0.063 13.5 0.0 0.11 12.8 0.0 1.5 1 1 0 1 1 1 0 Fascin domain TLP1_add_C PF18313.1 KFO98287.1 - 0.19 11.7 0.4 10 6.1 0.0 2.4 2 1 0 2 2 2 0 Thiolase-like protein type 1 additional C-terminal domain Nucleoplasmin PF03066.15 KFO98288.1 - 2.7e-34 117.7 0.0 3.3e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Nucleoplasmin/nucleophosmin domain Nitrophorin PF02087.15 KFO98288.1 - 0.0034 17.4 0.1 0.0043 17.1 0.1 1.1 1 0 0 1 1 1 1 Nitrophorin DUF1741 PF08427.10 KFO98289.1 - 3.1e-84 282.3 6.1 5.7e-84 281.4 6.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) HPS6 PF15702.5 KFO98290.1 - 0 1120.6 4.2 0 1120.4 4.2 1.0 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 6 protein Prominin PF05478.11 KFO98291.1 - 3.8e-100 336.1 0.1 4.2e-100 335.9 0.1 1.0 1 0 0 1 1 1 1 Prominin GrpE PF01025.19 KFO98291.1 - 0.014 15.1 2.9 0.023 14.4 1.5 1.8 1 1 1 2 2 2 0 GrpE GLYCAM-1 PF05242.11 KFO98291.1 - 0.066 13.3 0.2 0.11 12.7 0.2 1.3 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) LIM_bind PF01803.16 KFO98292.1 - 3.5e-54 183.9 9.0 3.1e-42 144.8 1.6 2.7 2 1 1 3 3 3 2 LIM-domain binding protein LID PF17916.1 KFO98292.1 - 1.7e-18 65.9 2.5 3e-18 65.2 2.5 1.4 1 0 0 1 1 1 1 LIM interaction domain (LID) RRM_1 PF00076.22 KFO98294.1 - 5.7e-09 35.7 0.0 1.2e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Apt1 PF10351.9 KFO98294.1 - 6.6 5.5 18.3 12 4.6 18.3 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain HTH_psq PF05225.16 KFO98295.1 - 1.4e-14 53.5 0.1 3.7e-14 52.2 0.0 1.8 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DUF4553 PF15090.6 KFO98296.1 - 9.5e-204 677.8 50.6 9.5e-204 677.8 50.6 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4553) LRR_8 PF13855.6 KFO98297.1 - 2.9e-101 331.2 79.2 4.2e-14 52.0 0.0 9.9 4 4 6 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 KFO98297.1 - 2.8e-41 138.8 50.7 2.6e-06 27.6 0.1 11.4 11 1 1 12 12 12 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFO98297.1 - 2.7e-36 124.4 6.0 3.2e-10 40.1 0.0 5.1 4 1 0 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFO98297.1 - 3.8e-23 81.9 15.5 0.002 17.6 0.0 6.1 4 2 2 6 6 6 6 Leucine-rich repeat LRRNT PF01462.18 KFO98297.1 - 6.6e-23 79.9 29.6 8e-09 34.9 1.5 5.6 4 0 0 4 4 4 3 Leucine rich repeat N-terminal domain EGF PF00008.27 KFO98297.1 - 4.1e-22 78.1 96.4 4.2e-08 33.3 5.9 8.7 9 0 0 9 9 7 5 EGF-like domain Laminin_G_2 PF02210.24 KFO98297.1 - 1.2e-21 77.6 0.1 2.1e-21 76.8 0.1 1.4 1 0 0 1 1 1 1 Laminin G domain LRRCT PF01463.24 KFO98297.1 - 2.6e-21 74.4 13.3 0.001 19.4 0.7 7.0 5 0 0 5 5 5 4 Leucine rich repeat C-terminal domain Laminin_G_1 PF00054.23 KFO98297.1 - 5.1e-21 75.3 0.0 8.2e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain hEGF PF12661.7 KFO98297.1 - 5.4e-08 33.2 25.1 4.5e-05 23.9 3.3 10.3 11 0 0 11 11 8 5 Human growth factor-like EGF LRR_1 PF00560.33 KFO98297.1 - 1.2e-06 28.2 46.6 0.52 11.1 0.0 13.7 15 2 1 16 16 13 5 Leucine Rich Repeat TPKR_C2 PF16920.5 KFO98297.1 - 0.00045 20.3 20.5 0.029 14.5 0.4 6.4 6 0 0 6 6 5 2 Tyrosine-protein kinase receptor C2 Ig-like domain EGF_CA PF07645.15 KFO98297.1 - 0.0015 18.7 7.4 0.0015 18.7 7.4 8.7 7 1 2 9 9 7 2 Calcium-binding EGF domain Laminin_G_3 PF13385.6 KFO98297.1 - 0.17 12.0 0.2 0.4 10.8 0.2 1.6 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily RhoGAP PF00620.27 KFO98298.1 - 9.1e-36 123.0 0.5 9.1e-36 123.0 0.5 1.6 2 0 0 2 2 2 1 RhoGAP domain NUC173 PF08161.12 KFO98299.1 - 2.8e-77 259.0 0.7 2.1e-73 246.3 0.0 3.9 5 0 0 5 5 5 2 NUC173 domain RPN7 PF10602.9 KFO98299.1 - 0.0048 16.6 0.3 18 5.0 0.0 4.0 3 1 0 3 3 3 1 26S proteasome subunit RPN7 HEAT PF02985.22 KFO98299.1 - 0.027 14.7 0.1 20 5.8 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat DUF3136 PF11334.8 KFO98299.1 - 0.12 12.2 0.0 21 5.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) F-protein PF00469.20 KFO98299.1 - 1.1 8.8 5.3 2.2 7.8 5.3 1.4 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef His_Phos_1 PF00300.22 KFO98300.1 - 8.7e-35 120.2 0.1 1.4e-26 93.4 0.1 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) EXOSC1 PF10447.9 KFO98301.1 - 1.4e-15 57.8 0.5 2.5e-12 47.3 0.2 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 DHHC PF01529.20 KFO98302.1 - 2.3e-30 105.5 13.1 2.3e-30 105.5 13.1 2.2 2 0 0 2 2 2 2 DHHC palmitoyltransferase MMS19_C PF12460.8 KFO98303.1 - 8.3e-117 390.9 1.0 8.3e-117 390.9 1.0 3.9 3 1 1 4 4 4 2 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 KFO98303.1 - 9e-89 297.5 0.1 9e-89 297.5 0.1 3.9 5 1 0 5 5 5 2 Dos2-interacting transcription regulator of RNA-Pol-II RTP1_C1 PF10363.9 KFO98303.1 - 0.0002 21.5 3.9 0.31 11.2 0.0 4.6 4 0 0 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 KFO98303.1 - 0.00042 20.6 14.0 0.0034 17.7 1.6 5.4 5 1 0 5 5 5 2 HEAT repeats Anticodon_1 PF08264.13 KFO98303.1 - 0.17 11.8 0.0 0.41 10.6 0.0 1.6 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA UBD PF16455.5 KFO98304.1 - 1.1e-37 128.5 0.0 1.7e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 KFO98304.1 - 2.7e-14 52.7 0.1 4.9e-14 51.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KFO98304.1 - 0.00013 21.7 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ank_4 PF13637.6 KFO98305.1 - 4.9e-05 23.8 0.0 8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFO98305.1 - 6.7e-05 23.4 0.0 9.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFO98305.1 - 0.0001 22.6 0.0 0.035 14.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFO98305.1 - 0.0032 17.8 0.1 0.23 12.1 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KFO98305.1 - 0.17 12.3 0.0 0.55 10.6 0.0 1.8 1 1 1 2 2 2 0 Ankyrin repeats (many copies) DHDPS PF00701.22 KFO98306.1 - 2e-53 181.0 0.0 2.2e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MORN PF02493.20 KFO98307.1 - 1e-25 88.0 21.3 1.4e-08 34.2 0.4 5.6 6 0 0 6 6 6 4 MORN repeat HCBP_related PF06594.11 KFO98307.1 - 0.01 15.7 1.4 0.072 13.1 0.0 2.6 3 0 0 3 3 3 0 Haemolysin-type calcium binding protein related domain PI3_PI4_kinase PF00454.27 KFO98308.1 - 5.4e-63 213.1 0.0 6.3e-63 212.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase MARVEL PF01284.23 KFO98309.1 - 3e-10 40.3 9.2 3.5e-10 40.1 9.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain FYVE PF01363.21 KFO98310.1 - 2.6e-08 33.9 11.3 2.6e-08 33.9 11.3 2.3 4 0 0 4 4 4 1 FYVE zinc finger FYVE_2 PF02318.16 KFO98310.1 - 4.2e-05 23.7 10.9 9.1e-05 22.7 7.2 2.4 2 0 0 2 2 2 1 FYVE-type zinc finger Pex24p PF06398.11 KFO98310.1 - 0.22 10.4 0.0 0.3 10.0 0.0 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin ADK_lid PF05191.14 KFO98310.1 - 6.1 6.9 11.8 1.1 9.3 3.0 3.4 3 1 0 3 3 3 0 Adenylate kinase, active site lid Erf4 PF10256.9 KFO98311.1 - 4.7e-33 113.7 0.0 5.5e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family VCBS PF13517.6 KFO98312.1 - 2.6e-29 101.6 16.4 2.6e-11 43.9 1.5 5.2 4 1 1 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella UnbV_ASPIC PF07593.12 KFO98312.1 - 4.5e-14 52.2 0.1 9.8e-14 51.1 0.1 1.6 1 0 0 1 1 1 1 ASPIC and UnbV FG-GAP PF01839.23 KFO98312.1 - 4.9e-12 45.7 17.3 0.0029 17.7 0.4 5.2 5 0 0 5 5 5 4 FG-GAP repeat EGF_CA PF07645.15 KFO98312.1 - 4.5e-11 42.8 6.9 4.5e-11 42.8 6.9 1.8 2 0 0 2 2 2 1 Calcium-binding EGF domain cEGF PF12662.7 KFO98312.1 - 0.0017 18.3 7.2 0.26 11.3 1.7 2.8 2 0 0 2 2 2 2 Complement Clr-like EGF-like Dockerin_1 PF00404.18 KFO98312.1 - 0.13 12.5 3.1 32 4.8 0.0 4.0 4 0 0 4 4 4 0 Dockerin type I domain NCBP3 PF10309.9 KFO98313.1 - 0.00016 21.5 0.0 0.0003 20.6 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 KFO98313.1 - 0.0043 17.0 0.0 0.0073 16.3 0.0 1.3 1 0 0 1 1 1 1 RNA binding domain SRCR PF00530.18 KFO98314.1 - 2.9e-90 297.3 22.8 1.2e-29 102.7 4.6 4.2 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFO98314.1 - 2.1e-17 63.5 10.8 0.00012 22.6 0.8 4.2 4 0 0 4 4 4 3 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFO98314.1 - 3.7e-11 43.5 0.1 0.02 15.4 0.0 3.6 3 0 0 3 3 3 3 Hepsin, SRCR domain CFEM PF05730.11 KFO98314.1 - 0.055 13.6 1.7 0.29 11.2 0.3 2.5 2 0 0 2 2 2 0 CFEM domain YecR PF13992.6 KFO98314.1 - 0.53 10.6 6.0 10 6.5 0.1 3.5 4 0 0 4 4 4 0 YecR-like lipoprotein Mon1 PF03164.14 KFO98315.1 - 0.013 14.6 0.0 3 6.8 0.0 2.4 2 0 0 2 2 2 0 Trafficking protein Mon1 Glyco_hydro_79n PF03662.14 KFO98316.1 - 2.5e-21 76.0 0.6 7.8e-21 74.3 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 79, N-terminal domain Aminotran_1_2 PF00155.21 KFO98318.1 - 3e-87 293.1 0.0 3.4e-87 293.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Mito_carr PF00153.27 KFO98319.1 - 1.7e-40 136.8 1.3 1.3e-20 73.1 0.6 2.0 1 1 1 2 2 2 2 Mitochondrial carrier protein SAT PF16073.5 KFO98319.1 - 0.0073 16.1 0.1 0.0081 15.9 0.1 1.3 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis NDUF_B6 PF09782.9 KFO98319.1 - 0.069 13.3 0.1 0.069 13.3 0.1 1.8 1 1 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit GDA1_CD39 PF01150.17 KFO98320.1 - 7.4e-92 308.2 0.0 9.8e-92 307.8 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family ATP_synt_H PF05493.13 KFO98321.1 - 3.5e-24 85.0 3.2 4.5e-24 84.7 3.2 1.1 1 0 0 1 1 1 1 ATP synthase subunit H COX15-CtaA PF02628.15 KFO98322.1 - 5.9e-102 341.0 3.7 6.7e-102 340.9 3.7 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF4807 PF16065.5 KFO98322.1 - 0.042 13.5 0.1 0.1 12.3 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4807) DUF2085 PF09858.9 KFO98322.1 - 2.3 8.8 5.8 11 6.6 0.2 2.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2085) CutC PF03932.14 KFO98323.1 - 8.6e-59 198.4 0.0 1.7e-58 197.5 0.0 1.4 2 0 0 2 2 2 1 CutC family ABC_membrane PF00664.23 KFO98324.1 - 5.6e-75 252.5 34.7 9.9e-38 130.3 12.9 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFO98324.1 - 1.4e-50 171.3 2.8 4e-27 95.4 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 KFO98324.1 - 1.7e-08 34.2 6.5 0.0079 15.7 0.8 4.4 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KFO98324.1 - 8.4e-07 29.1 1.5 0.013 15.5 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KFO98324.1 - 1.3e-06 28.9 0.1 0.085 13.2 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain MeaB PF03308.16 KFO98324.1 - 0.00012 21.2 2.7 0.0012 17.9 0.0 2.9 4 0 0 4 4 4 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 KFO98324.1 - 0.00029 20.8 2.6 0.63 9.9 0.1 2.7 2 1 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KFO98324.1 - 0.00059 19.5 1.7 0.15 11.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.13 KFO98324.1 - 0.0062 15.7 0.4 2.2 7.4 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 KFO98324.1 - 0.009 15.3 0.8 2 7.6 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin DUF3984 PF13136.6 KFO98324.1 - 0.013 14.9 0.1 0.031 13.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DUF87 PF01935.17 KFO98324.1 - 0.014 15.5 9.4 0.12 12.5 0.2 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_22 PF13401.6 KFO98324.1 - 0.019 15.3 1.3 9 6.6 0.0 3.4 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 KFO98324.1 - 0.023 13.8 0.1 5.1 6.1 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_21 PF13304.6 KFO98324.1 - 0.032 14.0 1.8 11 5.7 0.1 3.5 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 KFO98324.1 - 0.039 14.0 9.4 0.11 12.5 0.7 2.8 3 0 0 3 3 3 0 Dynamin family ATP_bind_1 PF03029.17 KFO98324.1 - 0.059 13.1 1.2 2.1 8.1 0.1 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 KFO98324.1 - 0.11 11.9 0.6 2.2 7.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.7 KFO98324.1 - 0.12 11.3 0.7 0.41 9.5 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain TrwB_AAD_bind PF10412.9 KFO98324.1 - 0.12 11.3 1.7 5.4 5.8 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 KFO98324.1 - 0.13 11.8 0.7 7.3 6.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 KFO98324.1 - 0.18 11.5 3.0 4.8 6.9 0.2 3.1 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 KFO98324.1 - 8.8 6.8 11.3 7.7 7.0 0.2 3.6 4 0 0 4 4 3 0 AAA domain BAR PF03114.18 KFO98325.1 - 2.5e-39 135.4 1.6 3.7e-39 134.8 1.6 1.2 1 0 0 1 1 1 1 BAR domain RhoGEF PF00621.20 KFO98325.1 - 4.3e-14 53.2 3.0 7.2e-14 52.4 0.0 2.4 2 1 0 2 2 2 1 RhoGEF domain SH3_1 PF00018.28 KFO98325.1 - 1.9e-11 43.4 0.0 1.8e-07 30.6 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KFO98325.1 - 9.8e-11 41.2 0.0 2.8e-05 23.7 0.0 2.8 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 KFO98325.1 - 2.8e-10 39.9 0.0 1e-07 31.7 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH3_3 PF08239.11 KFO98325.1 - 0.098 12.9 0.1 0.56 10.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial SH3 domain RhoGEF PF00621.20 KFO98326.1 - 2.3e-19 70.4 0.5 2.7e-19 70.1 0.5 1.0 1 0 0 1 1 1 1 RhoGEF domain GDA1_CD39 PF01150.17 KFO98327.1 - 1.2e-133 445.9 0.1 1.4e-133 445.6 0.1 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DDE_Tnp_IS1595 PF12762.7 KFO98327.1 - 0.15 12.1 0.1 0.25 11.4 0.1 1.3 1 0 0 1 1 1 0 ISXO2-like transposase domain Neur_chan_LBD PF02931.23 KFO98328.1 - 4.8e-49 166.7 0.1 6.9e-49 166.2 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFO98328.1 - 5.6e-23 82.2 9.9 1.9e-21 77.2 5.3 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region UQ_con PF00179.26 KFO98329.1 - 8.2e-47 158.4 0.0 1.1e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFO98329.1 - 0.009 15.7 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KFO98329.1 - 0.0094 16.2 0.1 0.015 15.6 0.1 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KFO98329.1 - 0.16 11.8 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 UEV domain DUF4663 PF15668.5 KFO98329.1 - 2.4 7.1 5.2 3.4 6.6 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) Integrin_alpha2 PF08441.12 KFO98330.1 - 9.4e-79 265.4 5.4 1.8e-76 257.9 0.9 2.1 1 1 1 2 2 2 2 Integrin alpha FG-GAP PF01839.23 KFO98330.1 - 1.1e-21 76.6 11.0 1.6e-09 37.7 0.0 3.9 3 0 0 3 3 3 3 FG-GAP repeat VCBS PF13517.6 KFO98330.1 - 8.5e-12 45.5 6.4 6.5e-08 33.1 0.2 2.7 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.20 KFO98330.1 - 0.00074 19.3 0.5 0.0016 18.3 0.5 1.6 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region DUF2207 PF09972.9 KFO98330.1 - 0.12 11.2 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DAGK_cat PF00781.24 KFO98331.1 - 1.9e-22 79.2 0.0 5.4e-22 77.8 0.0 1.8 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain HLH PF00010.26 KFO98332.1 - 1.5e-15 56.9 0.9 1.5e-15 56.9 0.9 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Neuro_bHLH PF12533.8 KFO98332.1 - 1.1e-08 36.2 0.9 3.3e-08 34.7 0.2 2.0 2 0 0 2 2 2 1 Neuronal helix-loop-helix transcription factor YL1 PF05764.13 KFO98332.1 - 0.00092 19.4 17.2 0.0011 19.2 17.2 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Nop14 PF04147.12 KFO98332.1 - 0.00097 17.5 13.2 0.0011 17.3 13.2 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 KFO98332.1 - 0.0018 16.7 15.9 0.002 16.5 15.9 1.0 1 0 0 1 1 1 1 CDC45-like protein Mpp10 PF04006.12 KFO98332.1 - 0.014 13.9 15.5 0.015 13.8 15.5 1.2 1 0 0 1 1 1 0 Mpp10 protein Nop53 PF07767.11 KFO98332.1 - 0.023 14.1 20.9 0.028 13.8 20.9 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Merozoite_SPAM PF07133.11 KFO98332.1 - 0.036 14.0 21.7 0.043 13.8 21.7 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Drc1-Sld2 PF11719.8 KFO98332.1 - 0.12 11.9 14.9 0.15 11.6 14.9 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Vfa1 PF08432.10 KFO98332.1 - 0.19 12.0 11.3 0.24 11.7 11.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PGA2 PF07543.12 KFO98332.1 - 0.87 9.6 17.4 1.2 9.1 17.4 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 RRN3 PF05327.11 KFO98332.1 - 2.1 6.8 9.8 2.6 6.5 9.8 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SpoIIIAH PF12685.7 KFO98332.1 - 3 7.6 8.7 4.5 7.1 8.7 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein RR_TM4-6 PF06459.12 KFO98332.1 - 3.9 7.2 13.3 4.7 6.9 13.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SSFA2_C PF14723.6 KFO98333.1 - 2.3e-81 272.0 13.0 8.2e-81 270.2 13.0 2.1 1 0 0 1 1 1 1 Sperm-specific antigen 2 C-terminus KRAP_IP3R_bind PF14722.6 KFO98333.1 - 2.9e-56 189.3 0.1 1e-55 187.5 0.1 2.0 1 0 0 1 1 1 1 Ki-ras-induced actin-interacting protein-IP3R-interacting domain DARPP-32 PF05395.12 KFO98334.1 - 2.5e-21 76.6 2.7 4.5e-21 75.7 2.7 1.4 1 1 0 1 1 1 1 Protein phosphatase inhibitor 1/DARPP-32 PDEase_I PF00233.19 KFO98335.1 - 2.4e-81 273.0 8.3 2.4e-81 273.0 8.3 1.4 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.12 KFO98335.1 - 4.3e-31 106.5 0.1 1.2e-30 105.1 0.1 1.8 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal Thioredoxin PF00085.20 KFO98336.1 - 1.2e-95 314.3 0.1 3.4e-24 84.8 0.1 6.0 6 0 0 6 6 6 4 Thioredoxin DnaJ PF00226.31 KFO98336.1 - 9.5e-24 83.3 2.5 2e-23 82.3 2.5 1.6 1 0 0 1 1 1 1 DnaJ domain Thioredoxin_2 PF13098.6 KFO98336.1 - 9.1e-15 55.1 2.1 0.00013 22.4 0.0 6.1 4 3 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_6 PF13848.6 KFO98336.1 - 9e-13 48.5 0.0 0.0017 18.3 0.0 3.8 2 2 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFO98336.1 - 1.2e-12 48.0 0.8 0.09 13.1 0.0 6.1 4 2 2 6 6 6 3 Thioredoxin-like OST3_OST6 PF04756.13 KFO98336.1 - 3.8e-10 39.6 0.0 0.021 14.2 0.0 4.3 3 1 1 4 4 4 3 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KFO98336.1 - 2.7e-09 37.1 2.8 0.23 11.6 0.0 4.6 4 0 0 4 4 4 3 Thioredoxin-like AhpC-TSA PF00578.21 KFO98336.1 - 8.6e-08 32.1 1.9 0.74 9.7 0.0 4.6 4 0 0 4 4 4 2 AhpC/TSA family Redoxin PF08534.10 KFO98336.1 - 1e-07 31.8 1.4 0.17 11.6 0.1 3.9 4 0 0 4 4 4 2 Redoxin Thioredoxin_9 PF14595.6 KFO98336.1 - 0.0001 22.1 1.4 4.5 7.0 0.1 3.7 2 1 0 3 3 3 2 Thioredoxin TraF PF13728.6 KFO98336.1 - 0.00038 20.4 0.5 0.14 12.0 0.0 3.6 4 0 0 4 4 4 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 KFO98336.1 - 0.0049 16.9 0.0 2.4 8.3 0.0 2.8 2 0 0 2 2 2 1 Thioredoxin domain RMMBL PF07521.12 KFO98336.1 - 0.053 13.5 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain DUF3228 PF11539.8 KFO98336.1 - 0.054 13.0 0.0 14 5.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3228) Calsequestrin PF01216.17 KFO98336.1 - 0.058 12.4 0.0 4.1 6.3 0.0 2.3 2 0 0 2 2 2 0 Calsequestrin Thioredoxin_5 PF13743.6 KFO98336.1 - 0.83 9.3 4.5 78 2.9 0.1 4.1 3 1 1 4 4 4 0 Thioredoxin PIP5K PF01504.18 KFO98337.1 - 4.1e-43 147.6 0.7 1.9e-33 115.9 0.5 2.5 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KFO98337.1 - 4.4e-33 114.6 0.2 8.2e-33 113.8 0.2 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KFO98337.1 - 9.4e-16 57.7 14.0 9.4e-16 57.7 14.0 2.3 2 0 0 2 2 2 1 FYVE zinc finger DEP PF00610.21 KFO98337.1 - 8.5e-05 22.5 0.0 0.0003 20.8 0.0 2.0 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Iso_dh PF00180.20 KFO98338.1 - 7.6e-61 206.2 0.0 3.1e-51 174.6 0.0 2.0 2 0 0 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase DUF3364 PF11844.8 KFO98338.1 - 0.12 12.7 0.4 3.6 7.9 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3364) Shugoshin_C PF07557.11 KFO98339.1 - 0.0017 18.1 2.3 0.004 16.9 2.3 1.7 1 0 0 1 1 1 1 Shugoshin C terminus DUF848 PF05852.11 KFO98340.1 - 0.15 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) p450 PF00067.22 KFO98343.1 - 2.6e-44 151.7 0.1 3.8e-44 151.2 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 RA PF00788.23 KFO98344.1 - 1.7e-13 51.0 2.8 4.1e-13 49.8 0.3 2.6 2 1 1 3 3 3 1 Ras association (RalGDS/AF-6) domain PH PF00169.29 KFO98344.1 - 4.6e-11 43.2 0.2 1e-10 42.0 0.2 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFO98344.1 - 0.0031 17.9 0.7 0.0031 17.9 0.7 2.9 2 2 0 2 2 2 1 Pleckstrin homology domain RBD PF02196.15 KFO98344.1 - 0.007 16.4 0.0 0.024 14.7 0.0 2.0 1 0 0 1 1 1 1 Raf-like Ras-binding domain FERM_N PF09379.10 KFO98344.1 - 0.02 14.8 0.2 0.048 13.6 0.2 1.7 1 0 0 1 1 1 0 FERM N-terminal domain V-set_2 PF15910.5 KFO98345.1 - 2.2e-11 43.8 0.2 4e-11 43.0 0.2 1.3 1 0 0 1 1 1 1 ICOS V-set domain V-set PF07686.17 KFO98345.1 - 3.5e-05 23.9 0.2 6.9e-05 23.0 0.2 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain V-set_2 PF15910.5 KFO98346.1 - 2.7e-08 33.9 0.1 3.7e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 ICOS V-set domain V-set PF07686.17 KFO98346.1 - 6e-08 32.8 0.0 8.1e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_6 PF18452.1 KFO98346.1 - 0.051 13.1 0.1 0.16 11.6 0.0 1.9 3 0 0 3 3 3 0 Immunoglobulin domain I-set PF07679.16 KFO98346.1 - 0.098 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO98346.1 - 0.12 13.0 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain V-set_2 PF15910.5 KFO98347.1 - 7e-36 122.8 2.4 1.2e-35 122.1 2.4 1.3 1 0 0 1 1 1 1 ICOS V-set domain Insulin_TMD PF17870.1 KFO98347.1 - 0.042 13.9 0.1 0.075 13.1 0.1 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment TMEM154 PF15102.6 KFO98347.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family PAS_3 PF08447.12 KFO98348.1 - 2.3e-20 72.7 0.1 1.4e-13 50.9 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KFO98348.1 - 3.1e-14 53.1 0.0 4.2e-12 46.2 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KFO98348.1 - 6e-10 39.1 0.0 2.3e-08 34.0 0.0 2.3 2 0 0 2 2 2 1 PAS fold HLH PF00010.26 KFO98348.1 - 4.6e-07 29.7 0.0 2.3e-06 27.4 0.1 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 KFO98348.1 - 5.4e-05 23.4 0.0 0.0027 17.9 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 KFO98348.1 - 0.0098 16.1 0.0 0.057 13.7 0.0 2.2 2 1 0 2 2 2 1 PAS fold Lipase_GDSL_2 PF13472.6 KFO98349.1 - 0.00095 19.6 0.0 0.0031 17.9 0.0 1.9 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 KFO98349.1 - 0.0035 16.6 0.0 0.0065 15.7 0.0 1.4 1 0 0 1 1 1 1 OSK domain Tmemb_cc2 PF10267.9 KFO98349.1 - 0.054 12.6 0.6 0.079 12.1 0.6 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein RasGEF_N_2 PF14663.6 KFO98349.1 - 0.088 13.2 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Lipase_GDSL PF00657.22 KFO98349.1 - 0.22 11.5 0.0 0.84 9.6 0.0 1.9 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Cadherin PF00028.17 KFO98350.1 - 3.6e-84 277.3 5.0 3.2e-19 69.1 0.0 5.4 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFO98350.1 - 2e-57 193.6 1.8 4e-57 192.6 1.8 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.12 KFO98350.1 - 5.2e-07 29.4 0.0 0.038 13.8 0.0 3.8 4 0 0 4 4 4 2 Cadherin-like Stevor PF17410.2 KFO98350.1 - 0.0033 17.0 0.1 0.0052 16.4 0.1 1.2 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame RET_CLD1 PF17756.1 KFO98350.1 - 0.023 15.0 0.0 2.2 8.6 0.0 3.1 3 0 0 3 3 3 0 RET Cadherin like domain 1 Cadherin_4 PF17803.1 KFO98350.1 - 0.047 14.3 0.3 0.047 14.3 0.3 4.6 6 0 0 6 6 5 0 Bacterial cadherin-like domain ASFV_J13L PF05568.11 KFO98350.1 - 0.05 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein Sigma_1s PF02454.16 KFO98350.1 - 0.062 13.3 0.1 3.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Sigma 1s protein Y_Y_Y PF07495.13 KFO98350.1 - 0.1 12.6 0.0 27 4.8 0.0 3.8 4 0 0 4 4 4 0 Y_Y_Y domain VirB3 PF05101.13 KFO98350.1 - 0.25 11.6 0.4 0.47 10.7 0.4 1.3 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein RIFIN PF02009.16 KFO98350.1 - 0.34 10.8 0.8 0.58 10.0 0.8 1.2 1 0 0 1 1 1 0 Rifin Cadherin PF00028.17 KFO98351.1 - 7.7e-80 263.5 5.3 2.6e-19 69.5 0.1 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFO98351.1 - 1.4e-57 194.1 0.4 2.7e-57 193.1 0.4 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_3 PF16184.5 KFO98351.1 - 7.3e-06 26.0 7.1 0.048 13.7 0.1 5.3 6 0 0 6 6 6 2 Cadherin-like Invasin_D3 PF09134.10 KFO98351.1 - 0.0027 18.0 1.4 5.7 7.3 0.1 4.2 4 0 0 4 4 4 1 Invasin, domain 3 Cadherin_2 PF08266.12 KFO98351.1 - 0.004 17.0 0.0 1.7 8.5 0.0 3.9 4 1 0 4 4 4 1 Cadherin-like Cadherin_pro PF08758.11 KFO98351.1 - 0.056 13.6 0.0 6.1 7.1 0.0 3.4 3 0 0 3 3 3 0 Cadherin prodomain like ASFV_J13L PF05568.11 KFO98351.1 - 0.069 12.9 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein Big_9 PF17963.1 KFO98351.1 - 0.084 13.6 9.8 24 5.7 1.4 4.6 4 0 0 4 4 4 0 Bacterial Ig domain Stevor PF17410.2 KFO98351.1 - 0.18 11.3 0.1 0.3 10.6 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Cadherin_4 PF17803.1 KFO98351.1 - 0.26 11.9 14.8 0.42 11.3 2.6 4.4 4 1 0 4 4 4 0 Bacterial cadherin-like domain RVT_1 PF00078.27 KFO98352.1 - 0.029 13.9 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Yae1_N PF09811.9 KFO98353.1 - 3.4e-19 68.3 72.3 1.8e+04 -24.9 72.3 5.6 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Cadherin PF00028.17 KFO98354.1 - 1.5e-81 268.9 6.9 3e-19 69.3 0.1 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFO98354.1 - 3e-56 189.8 0.4 5.7e-56 188.9 0.4 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_3 PF16184.5 KFO98354.1 - 7.7e-06 25.9 4.2 3.8 7.5 0.0 5.5 6 0 0 6 6 6 2 Cadherin-like Cadherin_2 PF08266.12 KFO98354.1 - 4e-05 23.4 0.0 0.51 10.2 0.0 3.4 3 0 0 3 3 3 2 Cadherin-like Invasin_D3 PF09134.10 KFO98354.1 - 0.00017 21.8 2.9 2.8 8.3 0.1 3.8 3 0 0 3 3 3 2 Invasin, domain 3 Stevor PF17410.2 KFO98354.1 - 0.025 14.1 0.1 0.042 13.4 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame ASFV_J13L PF05568.11 KFO98354.1 - 0.07 12.9 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Big_9 PF17963.1 KFO98354.1 - 2 9.2 9.1 6.8 7.5 0.6 4.1 4 0 0 4 4 4 0 Bacterial Ig domain HCO3_cotransp PF00955.21 KFO98355.1 - 1e-115 387.5 5.3 1.2e-115 387.3 5.3 1.0 1 0 0 1 1 1 1 HCO3- transporter family Cytochrom_B_C PF00032.17 KFO98355.1 - 0.021 15.1 3.4 0.53 10.6 0.1 3.0 2 1 1 3 3 3 0 Cytochrome b(C-terminal)/b6/petD MFS_MOT1 PF16983.5 KFO98355.1 - 0.44 11.0 5.8 0.35 11.3 2.6 2.2 1 1 0 2 2 2 0 Molybdate transporter of MFS superfamily ArfGap PF01412.18 KFO98356.1 - 2.1e-38 131.0 0.0 3.9e-38 130.1 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ras PF00071.22 KFO98356.1 - 3.9e-17 62.3 0.0 1.3e-16 60.6 0.0 1.7 2 0 0 2 2 2 1 Ras family PH PF00169.29 KFO98356.1 - 1e-10 42.1 1.2 2.9e-05 24.5 0.0 3.3 3 0 0 3 3 3 2 PH domain Ank_2 PF12796.7 KFO98356.1 - 6.2e-07 29.9 0.0 1.5e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFO98356.1 - 5.5e-06 26.8 0.0 0.0012 19.4 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KFO98356.1 - 9.4e-05 22.7 0.0 0.05 14.1 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat PH_6 PF15406.6 KFO98356.1 - 0.0025 18.1 0.0 0.0053 17.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Roc PF08477.13 KFO98356.1 - 0.025 14.8 0.0 0.094 12.9 0.0 2.0 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ank_5 PF13857.6 KFO98356.1 - 0.039 14.3 0.2 0.21 12.0 0.0 2.4 2 1 1 3 3 3 0 Ankyrin repeats (many copies) PH_11 PF15413.6 KFO98356.1 - 0.053 13.9 0.1 6.4 7.2 0.0 2.7 3 0 0 3 3 2 0 Pleckstrin homology domain Ank_3 PF13606.6 KFO98356.1 - 0.069 13.7 0.0 3.7 8.4 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat TniB PF05621.11 KFO98356.1 - 0.2 11.1 0.0 4.6 6.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein Ank_2 PF12796.7 KFO98357.1 - 7.1e-56 186.8 25.1 4.6e-14 52.8 0.1 4.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 KFO98357.1 - 2.2e-39 132.2 17.9 7e-06 26.2 0.3 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 KFO98357.1 - 9e-35 118.6 4.4 5.7e-08 33.2 0.0 8.1 3 2 5 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFO98357.1 - 3.6e-27 91.4 10.8 0.00038 20.7 0.1 8.6 8 1 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KFO98357.1 - 4e-26 90.7 6.9 4.8e-08 33.1 0.3 5.1 4 2 1 5 5 5 4 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFO98357.1 - 2.2e-08 34.3 5.8 2.2e-08 34.3 5.8 1.8 2 0 0 2 2 2 1 SOCS box ScdA_N PF04405.14 KFO98357.1 - 0.53 10.0 1.9 12 5.6 0.1 3.1 3 0 0 3 3 3 0 Domain of Unknown function (DUF542) ABC_tran PF00005.27 KFO98358.1 - 4.3e-47 160.1 0.0 1.7e-24 86.9 0.0 2.8 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 KFO98358.1 - 1e-21 76.7 3.7 1e-21 76.7 3.7 3.2 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.6 KFO98358.1 - 1.6e-15 57.7 1.9 0.0004 20.3 0.0 4.2 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFO98358.1 - 2.5e-06 27.1 0.5 1.1 8.7 0.0 3.8 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFO98358.1 - 6.7e-06 25.8 0.2 0.005 16.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFO98358.1 - 8e-05 22.6 0.0 0.018 15.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_15 PF13175.6 KFO98358.1 - 9.7e-05 22.2 3.0 0.031 14.0 0.1 3.4 4 0 0 4 4 4 1 AAA ATPase domain MMR_HSR1 PF01926.23 KFO98358.1 - 0.00011 22.2 0.0 0.019 15.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KFO98358.1 - 0.00014 22.1 0.1 0.13 12.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KFO98358.1 - 0.00018 22.0 0.0 0.37 11.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_24 PF13479.6 KFO98358.1 - 0.00057 19.7 0.4 0.77 9.5 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.6 KFO98358.1 - 0.0018 18.5 0.0 0.35 11.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain Rop PF01815.16 KFO98358.1 - 0.0021 17.9 2.2 0.18 11.7 0.1 2.8 2 0 0 2 2 2 1 Rop protein NACHT PF05729.12 KFO98358.1 - 0.0038 17.1 0.2 1.2 9.0 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 KFO98358.1 - 0.007 16.6 0.0 0.53 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KFO98358.1 - 0.0074 16.3 0.0 1.1 9.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 KFO98358.1 - 0.016 15.7 0.1 0.016 15.7 0.1 3.7 3 1 0 3 3 2 0 AAA domain AAA PF00004.29 KFO98358.1 - 0.021 15.3 0.1 2 8.8 0.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KFO98358.1 - 0.027 15.0 1.0 0.45 11.1 0.0 3.0 3 1 1 4 4 3 0 AAA domain AAA_27 PF13514.6 KFO98358.1 - 0.028 14.0 0.6 1.4 8.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KFO98358.1 - 0.038 13.7 0.0 0.34 10.6 0.0 2.4 3 0 0 3 3 2 0 AAA domain MeaB PF03308.16 KFO98358.1 - 0.044 12.8 2.5 3.3 6.6 0.0 2.9 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 KFO98358.1 - 0.061 13.3 0.2 6.7 6.7 0.2 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KFO98358.1 - 0.062 13.7 0.0 0.79 10.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 KFO98358.1 - 0.068 12.4 0.0 7.1 5.7 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Dynamin_N PF00350.23 KFO98358.1 - 0.099 12.7 0.1 0.35 10.9 0.0 2.0 2 0 0 2 2 2 0 Dynamin family Baculo_LEF5 PF04838.12 KFO98358.1 - 0.1 12.7 0.5 0.22 11.5 0.0 1.8 2 0 0 2 2 1 0 Baculoviridae late expression factor 5 IstB_IS21 PF01695.17 KFO98358.1 - 0.12 12.1 0.0 19 4.9 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF87 PF01935.17 KFO98358.1 - 1.5 8.9 3.4 1.7 8.7 0.0 2.8 3 1 1 4 4 4 0 Helicase HerA, central domain DUF3584 PF12128.8 KFO98358.1 - 2.2 5.7 7.2 0.47 7.9 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) CHGN PF05679.16 KFO98359.1 - 1.2e-143 479.7 0.0 1.6e-143 479.3 0.0 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 KFO98359.1 - 4e-10 39.6 0.1 7.5e-10 38.7 0.1 1.5 1 1 0 1 1 1 1 Fringe-like SWIB PF02201.18 KFO98361.1 - 1.7e-24 85.5 0.2 4.6e-24 84.1 0.2 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain CSD PF00313.22 KFO98362.1 - 1.4e-26 92.1 0.5 2.1e-26 91.5 0.5 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KFO98362.1 - 0.0066 16.1 0.0 0.019 14.7 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease B OB domain Synaptonemal_3 PF15191.6 KFO98363.1 - 5.3e-34 115.9 5.7 5.8e-34 115.7 5.7 1.0 1 0 0 1 1 1 1 Synaptonemal complex central element protein 3 Pkinase_Tyr PF07714.17 KFO98364.1 - 3.7e-63 213.2 0.0 5.5e-63 212.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO98364.1 - 1.9e-29 102.8 0.0 3e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KFO98364.1 - 0.00028 20.3 0.0 0.0005 19.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like EphA2_TM PF14575.6 KFO98364.1 - 0.029 15.2 0.0 0.066 14.1 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Calc_CGRP_IAPP PF00214.19 KFO98364.1 - 0.11 12.9 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family TMEM154 PF15102.6 KFO98364.1 - 0.15 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Atg8 PF02991.16 KFO98365.1 - 1.2e-39 134.7 0.0 1.3e-39 134.6 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KFO98365.1 - 1.7e-08 34.7 0.0 1.8e-08 34.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 TMEM52 PF14979.6 KFO98366.1 - 8.8e-61 204.2 0.4 1e-60 204.0 0.4 1.0 1 0 0 1 1 1 1 Transmembrane 52 Herpes_LMP2 PF07415.11 KFO98366.1 - 0.066 12.0 1.3 0.083 11.7 0.8 1.4 2 0 0 2 2 2 0 Gammaherpesvirus latent membrane protein (LMP2) protein DUF4131 PF13567.6 KFO98366.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) WBP-1 PF11669.8 KFO98366.1 - 0.21 12.2 3.6 0.4 11.3 3.6 1.6 1 1 0 1 1 1 0 WW domain-binding protein 1 Prominin PF05478.11 KFO98366.1 - 0.36 8.7 2.7 0.48 8.3 2.7 1.1 1 0 0 1 1 1 0 Prominin Lectin_C PF00059.21 KFO98367.1 - 4.6e-13 49.8 1.8 4.6e-13 49.8 1.8 2.4 3 0 0 3 3 3 1 Lectin C-type domain DUF2897 PF11446.8 KFO98367.1 - 0.25 11.2 0.9 0.47 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) UL45 PF05473.12 KFO98367.1 - 4.6 6.8 7.4 42 3.7 7.4 2.2 1 1 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Cys_knot PF00007.22 KFO98368.1 - 2.2e-31 108.2 14.6 2.6e-31 108.0 14.6 1.0 1 0 0 1 1 1 1 Cystine-knot domain SCP-1 PF05483.12 KFO98369.1 - 4.5e-208 693.0 157.1 1.4e-206 688.1 157.1 2.4 1 1 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) NifT PF06988.11 KFO98369.1 - 0.097 12.5 2.7 6.2 6.7 0.1 3.4 2 0 0 2 2 2 0 NifT/FixU protein zf-C4 PF00105.18 KFO98370.1 - 4.5e-29 100.7 13.3 4.5e-29 100.7 13.3 1.9 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFO98370.1 - 7.2e-22 78.0 0.6 4.1e-21 75.5 0.1 2.2 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor CSD PF00313.22 KFO98371.1 - 3.2e-81 267.2 15.0 7.3e-17 61.0 0.1 8.1 8 0 0 8 8 8 5 'Cold-shock' DNA-binding domain S1-like PF14444.6 KFO98371.1 - 4.2e-12 45.8 10.1 0.053 13.5 0.0 6.9 7 0 0 7 7 7 4 S1-like SUZ-C PF12901.7 KFO98371.1 - 8.4e-12 44.9 0.7 5.7e-11 42.2 0.1 2.4 2 0 0 2 2 2 1 SUZ-C motif CusF_Ec PF11604.8 KFO98371.1 - 2.2e-08 34.0 6.6 0.066 13.2 0.0 6.8 7 0 0 7 7 7 3 Copper binding periplasmic protein CusF GbpA_2 PF18416.1 KFO98371.1 - 0.00067 19.9 0.3 26 5.2 0.0 5.3 5 0 0 5 5 5 0 N-acetylglucosamine binding protein domain 2 MazE_antitoxin PF04014.18 KFO98371.1 - 0.02 14.8 6.2 7.6 6.6 0.1 5.2 5 0 0 5 5 5 0 Antidote-toxin recognition MazE, bacterial antitoxin DUF3857 PF12969.7 KFO98371.1 - 0.022 14.9 0.1 9.4 6.3 0.0 3.7 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3857) Herpes_Helicase PF02689.14 KFO98371.1 - 0.15 10.0 0.0 0.25 9.2 0.0 1.2 1 0 0 1 1 1 0 Helicase OB_RNB PF08206.11 KFO98371.1 - 0.58 9.9 10.1 26 4.6 0.1 5.0 5 0 0 5 5 5 0 Ribonuclease B OB domain Ras PF00071.22 KFO98372.1 - 3.3e-58 195.9 0.1 3.8e-58 195.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO98372.1 - 3.7e-21 75.6 0.0 6.8e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO98372.1 - 8.2e-09 35.2 0.0 9.9e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFO98372.1 - 6.6e-07 29.1 0.1 5.7e-06 26.0 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFO98372.1 - 3.8e-06 26.9 0.0 0.016 15.1 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFO98372.1 - 5.6e-05 23.2 0.0 9.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFO98372.1 - 0.00085 18.9 0.1 0.0069 15.9 0.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B G-alpha PF00503.20 KFO98372.1 - 0.044 12.9 0.0 1.5 7.9 0.0 2.0 1 1 0 2 2 2 0 G-protein alpha subunit Septin PF00735.18 KFO98372.1 - 0.059 12.6 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Septin DUF2075 PF09848.9 KFO98372.1 - 0.064 12.5 0.1 6 6.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Ldh_1_N PF00056.23 KFO98372.1 - 0.077 13.1 0.0 0.44 10.6 0.0 1.9 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain ParA PF10609.9 KFO98372.1 - 0.1 12.0 0.0 0.68 9.3 0.0 1.9 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase ATP_bind_1 PF03029.17 KFO98372.1 - 0.13 12.1 0.4 3.1 7.5 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein CbiA PF01656.23 KFO98372.1 - 0.15 12.1 0.4 0.63 10.1 0.4 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 KFO98372.1 - 0.19 11.3 0.0 0.43 10.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain A_deaminase PF00962.22 KFO98373.1 - 3.1e-131 437.6 0.8 2.9e-130 434.4 0.8 2.1 1 1 0 1 1 1 1 Adenosine/AMP deaminase DENN PF02141.21 KFO98374.1 - 1e-59 201.6 1.1 1e-59 201.6 1.1 2.2 3 0 0 3 3 3 1 DENN (AEX-3) domain uDENN PF03456.18 KFO98374.1 - 2.1e-16 60.4 0.7 6e-16 58.9 0.7 1.9 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KFO98374.1 - 4.5e-08 33.0 3.7 1.1e-07 31.7 2.1 2.5 2 0 0 2 2 2 1 dDENN domain BCAS2 PF05700.11 KFO98375.1 - 5e-57 192.9 13.5 6.1e-57 192.6 13.5 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) HAUS2 PF15003.6 KFO98375.1 - 0.0028 17.4 1.5 0.0038 17.0 0.7 1.6 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 2 THOC7 PF05615.13 KFO98375.1 - 0.011 16.0 3.3 0.011 16.0 3.3 2.2 1 1 1 2 2 2 0 Tho complex subunit 7 SCRG1 PF15224.6 KFO98375.1 - 0.023 14.8 0.1 0.04 14.0 0.1 1.4 1 0 0 1 1 1 0 Scrapie-responsive protein 1 Cep57_CLD PF14073.6 KFO98375.1 - 0.023 14.7 12.9 0.037 14.0 12.9 1.4 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 DUF4201 PF13870.6 KFO98375.1 - 0.025 14.3 10.0 0.16 11.7 7.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Filament PF00038.21 KFO98375.1 - 0.027 14.0 11.3 0.036 13.6 10.8 1.4 1 1 0 1 1 1 0 Intermediate filament protein Mesd PF10185.9 KFO98375.1 - 0.029 14.3 3.4 0.64 9.9 0.5 2.2 1 1 1 2 2 2 0 Chaperone for wingless signalling and trafficking of LDL receptor Tup_N PF08581.10 KFO98375.1 - 0.038 14.3 11.8 0.21 11.9 2.4 3.2 1 1 2 3 3 3 0 Tup N-terminal CENP-F_leu_zip PF10473.9 KFO98375.1 - 0.054 13.5 10.1 0.099 12.7 10.1 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 KFO98375.1 - 0.058 13.2 7.2 1.5 8.6 1.2 2.6 2 0 0 2 2 2 0 Septum formation initiator DUF2508 PF10704.9 KFO98375.1 - 0.069 13.3 0.5 0.069 13.3 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) TMF_DNA_bd PF12329.8 KFO98375.1 - 0.073 13.1 6.9 0.23 11.5 6.9 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF4140 PF13600.6 KFO98375.1 - 0.082 13.4 1.6 3.1 8.3 0.1 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) OmpH PF03938.14 KFO98375.1 - 0.099 13.0 6.3 0.15 12.4 6.2 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Phlebovirus_NSM PF07246.11 KFO98375.1 - 0.1 12.0 5.8 0.13 11.6 5.8 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Cep57_MT_bd PF06657.13 KFO98375.1 - 0.12 12.9 7.9 2.5 8.6 1.4 3.2 2 2 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Ribosomal_L29 PF00831.23 KFO98375.1 - 0.19 11.7 6.6 1.6 8.7 1.9 2.4 2 0 0 2 2 2 0 Ribosomal L29 protein bZIP_1 PF00170.21 KFO98375.1 - 0.36 11.0 5.2 9.7 6.4 0.1 2.8 2 1 0 2 2 2 0 bZIP transcription factor DUF724 PF05266.14 KFO98375.1 - 0.44 10.3 7.3 1.4 8.7 7.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF3450 PF11932.8 KFO98375.1 - 0.47 9.7 13.3 0.38 10.0 4.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) PRKG1_interact PF15898.5 KFO98375.1 - 0.48 11.3 11.9 0.11 13.4 5.2 2.3 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Uso1_p115_C PF04871.13 KFO98375.1 - 0.6 10.5 8.3 1.4 9.3 6.1 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1192 PF06698.11 KFO98375.1 - 0.93 9.6 4.9 3.6 7.7 0.2 3.3 4 0 0 4 4 3 0 Protein of unknown function (DUF1192) FlaC_arch PF05377.11 KFO98375.1 - 1.1 9.7 6.9 2.3 8.7 0.2 2.9 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) GIT_CC PF16559.5 KFO98375.1 - 1.8 8.5 10.9 3.6 7.5 3.3 2.6 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cnn_1N PF07989.11 KFO98375.1 - 2.7 8.2 9.7 9.3 6.5 1.5 2.6 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 GvpK PF05121.12 KFO98375.1 - 3.1 7.9 7.0 1.7 8.7 0.3 3.0 2 2 1 3 3 3 0 Gas vesicle protein K GPS2_interact PF15784.5 KFO98375.1 - 3.7 8.0 7.8 5.2 7.6 1.7 2.6 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain Csm1_N PF18504.1 KFO98375.1 - 5.8 7.3 12.0 0.54 10.6 1.2 2.8 3 0 0 3 3 3 0 Csm1 N-terminal domain ABC_tran_CTD PF16326.5 KFO98375.1 - 6.5 7.1 10.5 10 6.5 1.9 3.2 2 1 1 3 3 3 0 ABC transporter C-terminal domain Bromodomain PF00439.25 KFO98376.1 - 3e-23 81.7 0.3 9.4e-23 80.1 0.3 1.9 1 0 0 1 1 1 1 Bromodomain zf-B_box PF00643.24 KFO98376.1 - 4.4e-12 45.9 19.8 1.6e-09 37.7 6.7 4.8 5 0 0 5 5 5 2 B-box zinc finger PHD PF00628.29 KFO98376.1 - 4e-08 33.0 9.5 4e-08 33.0 9.5 4.6 5 0 0 5 5 5 1 PHD-finger Exonuc_VII_L PF02601.15 KFO98376.1 - 8.7 5.8 10.5 7.2 6.1 3.7 2.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit C2 PF00168.30 KFO98377.1 - 1.4e-54 182.7 0.0 4.5e-26 91.1 0.0 3.1 3 0 0 3 3 3 2 C2 domain PI3K_C2 PF00792.24 KFO98377.1 - 0.00038 20.4 0.1 0.12 12.3 0.0 3.1 4 0 0 4 4 4 2 Phosphoinositide 3-kinase C2 CEP76-C2 PF15627.6 KFO98377.1 - 0.00057 19.5 0.0 0.085 12.4 0.0 2.7 3 0 0 3 3 3 2 CEP76 C2 domain DOCK-C2 PF14429.6 KFO98377.1 - 0.043 13.6 0.3 2.2 8.0 0.0 2.2 1 1 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins LapA_dom PF06305.11 KFO98377.1 - 0.21 11.4 1.9 0.49 10.2 1.9 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Pkinase PF00069.25 KFO98378.1 - 1.2e-50 172.4 0.0 2.1e-50 171.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO98378.1 - 3.3e-24 85.6 0.0 5.2e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFO98378.1 - 4.3e-06 26.2 0.1 3.3e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFO98378.1 - 0.0084 14.9 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFO98378.1 - 0.015 15.3 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KFO98378.1 - 0.019 14.0 0.1 0.036 13.0 0.1 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Lactamase_B_2 PF12706.7 KFO98379.1 - 2.2e-09 37.1 0.2 3.9e-09 36.3 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 KFO98379.1 - 2.5e-09 37.3 0.3 5.8e-09 36.1 0.3 1.7 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 KFO98379.1 - 0.011 15.7 2.3 0.037 14.0 2.3 1.8 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily RMMBL PF07521.12 KFO98379.1 - 0.023 14.6 0.0 0.068 13.1 0.0 1.7 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain Adaptin_N PF01602.20 KFO98380.1 - 4.7e-33 114.5 0.0 5.1e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 KFO98380.1 - 0.001 19.4 0.1 0.15 12.5 0.0 3.4 3 1 0 3 3 3 1 HEAT repeats HEAT PF02985.22 KFO98380.1 - 0.0065 16.6 2.2 11 6.5 0.0 4.7 3 1 1 4 4 4 1 HEAT repeat Phtf-FEM1B_bdg PF12129.8 KFO98382.1 - 1e-50 171.6 2.7 3.4e-50 169.9 2.7 2.0 1 0 0 1 1 1 1 Male germ-cell putative homeodomain transcription factor PDZ PF00595.24 KFO98383.1 - 1.8e-65 217.3 6.9 2.1e-15 56.8 0.4 5.5 5 0 0 5 5 5 5 PDZ domain PDZ_6 PF17820.1 KFO98383.1 - 3.5e-46 154.8 16.0 2.9e-13 49.4 0.7 5.5 5 0 0 5 5 5 5 PDZ domain PDZ_2 PF13180.6 KFO98383.1 - 9.6e-26 89.9 0.1 0.0001 22.5 0.0 5.4 5 0 0 5 5 5 5 PDZ domain WW PF00397.26 KFO98383.1 - 2.6e-17 62.6 5.3 1.3e-08 34.8 0.1 2.4 2 0 0 2 2 2 2 WW domain Guanylate_kin PF00625.21 KFO98383.1 - 4.8e-10 39.4 0.0 9.4e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase Tricorn_PDZ PF14685.6 KFO98383.1 - 1.9e-05 24.5 5.3 0.32 11.0 0.1 4.7 5 0 0 5 5 5 2 Tricorn protease PDZ domain MAGI_u1 PF16663.5 KFO98383.1 - 2.8e-05 24.1 5.4 2.8e-05 24.1 5.4 2.3 2 0 0 2 2 2 1 Unstructured region on MAGI OB_RNB PF08206.11 KFO98383.1 - 0.07 12.8 0.9 48 3.7 0.0 4.1 4 0 0 4 4 4 0 Ribonuclease B OB domain MFS_1 PF07690.16 KFO98384.1 - 1.1e-28 100.2 32.5 7e-22 77.8 22.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0542 PF15086.6 KFO98384.1 - 0.15 12.0 0.0 0.54 10.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 TMEMspv1-c74-12 PF11044.8 KFO98384.1 - 0.7 9.9 3.8 0.39 10.7 0.1 2.5 3 0 0 3 3 3 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein TAFA PF12020.8 KFO98385.1 - 9.4e-33 112.5 8.3 1.1e-32 112.3 8.3 1.1 1 0 0 1 1 1 1 TAFA family PP2C PF00481.21 KFO98386.1 - 4.1e-27 95.4 0.0 7.5e-13 48.7 0.0 3.0 3 0 0 3 3 3 3 Protein phosphatase 2C SpoIIE PF07228.12 KFO98386.1 - 3.4e-05 23.9 0.0 0.012 15.5 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Ras PF00071.22 KFO98387.1 - 3.1e-58 196.0 0.0 3.5e-58 195.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO98387.1 - 2.5e-23 82.6 0.0 3.4e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO98387.1 - 2.3e-10 40.2 0.0 4.1e-10 39.4 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFO98387.1 - 0.00015 21.4 0.0 0.00029 20.4 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFO98387.1 - 0.042 13.3 0.0 0.069 12.6 0.0 1.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFO98387.1 - 0.043 13.2 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_12 PF13087.6 KFO98388.1 - 8.3e-47 159.4 0.0 1.4e-46 158.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFO98388.1 - 6e-25 88.5 0.0 3.2e-11 43.5 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 KFO98388.1 - 6.2e-11 42.4 0.0 1.7e-10 40.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFO98388.1 - 1.8e-07 31.6 0.0 1.2e-06 28.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 KFO98388.1 - 5.1e-05 23.3 0.0 0.0001 22.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.29 KFO98388.1 - 0.0053 17.2 0.0 0.15 12.5 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFO98388.1 - 0.006 16.9 0.0 0.02 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KFO98388.1 - 0.0084 15.9 0.0 0.025 14.4 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PIF1 PF05970.14 KFO98388.1 - 0.014 14.6 0.0 0.86 8.7 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_16 PF13191.6 KFO98388.1 - 0.11 12.9 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KFO98388.1 - 0.18 11.3 0.0 0.42 10.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region F-actin_cap_A PF01267.17 KFO98389.1 - 1.2e-105 352.8 0.5 1.3e-105 352.6 0.5 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit CCP_MauG PF03150.14 KFO98389.1 - 0.0094 16.6 0.1 0.11 13.1 0.0 2.3 1 1 0 1 1 1 1 Di-haem cytochrome c peroxidase DUF2808 PF10989.8 KFO98389.1 - 0.085 12.8 0.2 0.13 12.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) ST7 PF04184.12 KFO98390.1 - 3.2e-285 946.7 1.5 3.6e-285 946.5 1.5 1.0 1 0 0 1 1 1 1 ST7 protein TPR_6 PF13174.6 KFO98390.1 - 0.0018 18.8 0.3 0.0089 16.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Clathrin PF00637.20 KFO98390.1 - 0.036 13.9 0.2 0.074 12.9 0.2 1.5 1 0 0 1 1 1 0 Region in Clathrin and VPS TPR_2 PF07719.17 KFO98390.1 - 0.042 14.0 4.1 2 8.8 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFO98390.1 - 0.064 13.1 3.7 11 6.1 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFO98390.1 - 0.23 12.0 0.1 0.23 12.0 0.1 3.6 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFO98390.1 - 4.1 8.5 12.5 18 6.5 0.7 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat wnt PF00110.19 KFO98391.1 - 5.6e-124 413.7 28.7 6.3e-124 413.5 28.7 1.0 1 0 0 1 1 1 1 wnt family CortBP2 PF09727.9 KFO98392.1 - 4.9e-68 228.8 21.1 4.9e-68 228.8 21.1 2.4 2 0 0 2 2 2 1 Cortactin-binding protein-2 Rootletin PF15035.6 KFO98392.1 - 0.79 9.7 36.4 0.8 9.7 13.4 2.6 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Mucin2_WxxW PF13330.6 KFO98392.1 - 4.4 8.2 5.4 1.6 9.6 0.1 2.7 2 1 0 2 2 2 0 Mucin-2 protein WxxW repeating region hDGE_amylase PF14701.6 KFO98392.1 - 7.8 5.5 11.9 14 4.6 11.9 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain DUF812 PF05667.11 KFO98392.1 - 8.6 5.1 31.6 16 4.2 31.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) BTB_2 PF02214.22 KFO98393.1 - 2.2e-29 101.6 0.1 4.7e-29 100.6 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.31 KFO98393.1 - 6.7e-29 100.8 14.0 1.1e-28 100.1 14.0 1.4 1 0 0 1 1 1 1 Ion transport protein Shal-type PF11601.8 KFO98393.1 - 1e-14 53.7 12.1 1.7e-14 53.0 12.1 1.3 1 0 0 1 1 1 1 Shal-type voltage-gated potassium channels, N-terminal BTB_3 PF16017.5 KFO98393.1 - 2.2e-05 24.5 0.0 6e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain PKD_channel PF08016.12 KFO98393.1 - 0.088 11.5 10.6 0.16 10.7 10.6 1.5 1 1 0 1 1 1 0 Polycystin cation channel Ion_trans_2 PF07885.16 KFO98393.1 - 1.4 9.0 14.7 0.059 13.3 4.3 2.8 3 0 0 3 3 3 0 Ion channel DUF3399 PF11879.8 KFO98394.1 - 6.6e-46 154.9 11.9 6.6e-46 154.9 11.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3399) Ion_trans PF00520.31 KFO98394.1 - 2.2e-06 27.1 0.0 2.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFO98394.1 - 0.0011 18.9 0.1 0.0016 18.4 0.1 1.3 1 0 0 1 1 1 1 Ion channel DEAD PF00270.29 KFO98395.1 - 2.9e-30 105.3 0.0 5.4e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFO98395.1 - 2.3e-25 89.1 0.0 4.3e-24 85.0 0.0 2.6 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFO98395.1 - 1.7e-05 24.9 0.0 3.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KFO98395.1 - 0.011 16.1 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFO98395.1 - 0.02 14.6 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFO98395.1 - 0.027 14.8 0.1 0.12 12.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KFO98395.1 - 0.086 13.3 0.0 0.7 10.3 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CMS1 PF14617.6 KFO98395.1 - 0.29 10.4 0.0 0.29 10.4 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit FAM212 PF15342.6 KFO98396.1 - 1.3e-28 98.5 1.6 2.9e-28 97.4 0.7 2.2 1 1 1 2 2 2 1 FAM212 family Ras PF00071.22 KFO98397.1 - 2e-53 180.3 0.3 2.3e-53 180.1 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO98397.1 - 6.6e-21 74.7 0.0 9.9e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO98397.1 - 4.7e-09 35.9 0.1 5.1e-09 35.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFO98397.1 - 5.3e-05 22.8 0.2 0.00012 21.7 0.1 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFO98397.1 - 0.00052 20.1 0.0 0.00071 19.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KFO98397.1 - 0.001 18.4 0.0 0.0046 16.2 0.0 1.8 1 1 0 1 1 1 1 G-protein alpha subunit RsgA_GTPase PF03193.16 KFO98397.1 - 0.0025 17.8 2.5 0.94 9.4 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase 7tm_1 PF00001.21 KFO98398.1 - 4e-44 150.9 15.7 4.6e-44 150.7 15.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFO98398.1 - 9e-12 45.3 5.1 1.4e-11 44.6 5.1 1.4 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KFO98398.1 - 3.6e-11 42.9 16.8 4.3e-11 42.7 16.8 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFO98398.1 - 0.0014 18.3 17.4 0.0014 18.3 17.4 1.7 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Mt_ATP-synt_B PF05405.14 KFO98399.1 - 1.9e-50 170.7 11.3 2.1e-50 170.5 11.3 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) EF-hand_1 PF00036.32 KFO98401.1 - 3.3e-21 73.2 13.3 4.6e-06 25.8 0.0 5.0 4 1 1 5 5 5 3 EF hand EF-hand_7 PF13499.6 KFO98401.1 - 9.1e-21 74.1 3.3 6.9e-14 52.1 0.4 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KFO98401.1 - 1.6e-19 68.1 7.6 1.9e-05 24.2 0.0 4.8 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KFO98401.1 - 2.4e-15 56.1 3.6 1.2e-08 34.6 0.6 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KFO98401.1 - 1.1e-11 43.6 9.4 2.1e-05 23.8 1.3 4.2 4 1 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 KFO98401.1 - 2.5e-07 31.0 0.7 0.00056 20.2 0.1 2.9 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFO98401.1 - 1.5e-05 24.8 3.1 0.36 10.8 0.0 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KFO98401.1 - 0.00028 21.0 0.5 0.018 15.2 0.3 2.7 2 1 1 3 3 3 2 Dockerin type I domain VCBS PF13517.6 KFO98401.1 - 0.0023 18.5 0.1 1.5 9.5 0.0 3.0 3 0 0 3 3 3 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Caleosin PF05042.13 KFO98401.1 - 0.092 12.7 0.7 8.1 6.3 0.0 2.9 1 1 1 3 3 3 0 Caleosin related protein DUF4891 PF16232.5 KFO98401.1 - 0.099 13.2 0.0 7 7.2 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4891) FG-GAP PF01839.23 KFO98401.1 - 3.8 7.7 8.0 3.7 7.8 0.2 2.9 3 0 0 3 3 3 0 FG-GAP repeat EF-hand_1 PF00036.32 KFO98402.1 - 1.7e-22 77.2 10.9 9.9e-07 27.9 0.3 4.2 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 KFO98402.1 - 2.9e-21 75.7 1.9 4.3e-14 52.7 0.1 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFO98402.1 - 5.1e-20 69.6 4.4 4.5e-05 23.0 0.1 4.7 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 KFO98402.1 - 9.8e-15 54.1 1.4 9.8e-07 28.5 0.1 3.6 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KFO98402.1 - 1e-14 53.2 10.9 8.9e-05 21.8 0.3 4.2 5 0 0 5 5 5 3 EF hand SPARC_Ca_bdg PF10591.9 KFO98402.1 - 6.2e-07 29.7 0.4 0.39 11.1 0.0 3.2 1 1 2 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFO98402.1 - 0.0031 17.4 1.9 2.2 8.2 0.1 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand ATG16 PF08614.11 KFO98403.1 - 0.43 10.8 58.2 0.048 13.9 28.2 4.0 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) Phage_int_SAM_2 PF12834.7 KFO98403.1 - 0.53 11.0 12.0 3.6 8.3 3.3 4.2 4 1 0 4 4 4 0 Phage integrase, N-terminal DUF948 PF06103.11 KFO98403.1 - 3.2 8.1 6.8 22 5.4 6.8 2.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 KFO98403.1 - 5.3 7.1 18.9 0.77 9.8 10.5 3.0 1 1 2 3 3 3 0 Laminin Domain II PEARLI-4 PF05278.12 KFO98403.1 - 5.6 6.5 30.0 0.55 9.8 8.0 3.2 3 0 0 3 3 3 0 Arabidopsis phospholipase-like protein (PEARLI 4) adh_short PF00106.25 KFO98404.1 - 1.8e-40 138.5 0.1 2.3e-40 138.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFO98404.1 - 6.3e-22 78.3 0.0 8e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFO98404.1 - 3.8e-07 30.2 0.3 1.4e-06 28.4 0.3 1.8 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFO98404.1 - 2.8e-06 26.9 0.0 3.7e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) SE PF08491.10 KFO98404.1 - 0.11 11.6 0.1 0.26 10.3 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase adh_short PF00106.25 KFO98405.1 - 4.3e-48 163.4 0.3 5.5e-48 163.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFO98405.1 - 1.3e-25 90.3 0.1 1.7e-25 90.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFO98405.1 - 8.4e-09 35.6 1.6 7.6e-08 32.5 1.6 2.0 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFO98405.1 - 6.4e-05 22.5 0.0 9.4e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Shikimate_DH PF01488.20 KFO98405.1 - 0.0011 19.0 0.2 0.0018 18.3 0.2 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 KFO98405.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FMO-like PF00743.19 KFO98405.1 - 0.035 12.5 0.0 0.061 11.7 0.0 1.4 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like NAD_binding_2 PF03446.15 KFO98405.1 - 0.086 13.0 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KFO98405.1 - 0.1 11.9 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain G0-G1_switch_2 PF15103.6 KFO98406.1 - 6.8e-39 132.5 0.1 7.6e-39 132.4 0.1 1.0 1 0 0 1 1 1 1 G0/G1 switch protein 2 Laminin_N PF00055.17 KFO98407.1 - 2.5e-54 184.4 0.0 2.5e-54 184.4 0.0 3.3 3 1 1 4 4 4 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 KFO98407.1 - 6e-33 112.7 113.5 4e-11 42.9 13.4 7.1 6 2 1 7 7 7 5 Laminin EGF domain F5_F8_type_C PF00754.25 KFO98407.1 - 0.0023 18.0 0.0 0.0047 17.0 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain DUF1732 PF08340.11 KFO98407.1 - 0.026 14.5 0.7 1.3 9.0 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1732) DUF948 PF06103.11 KFO98407.1 - 0.12 12.7 16.0 1.3 9.4 0.6 5.2 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 KFO98407.1 - 0.52 10.4 21.7 2.4 8.2 1.2 5.2 4 1 2 6 6 6 0 Protein of unknown function (DUF1664) GAS PF13851.6 KFO98407.1 - 0.8 9.0 26.8 0.84 9.0 9.3 4.4 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 KFO98407.1 - 4.3 7.3 27.2 0.51 10.3 0.3 5.4 3 2 2 5 5 5 0 Laminin Domain II DUF5082 PF16888.5 KFO98407.1 - 6.3 7.1 25.6 1.6 9.0 0.6 5.3 5 1 1 6 6 6 0 Domain of unknown function (DUF5082) IFT57 PF10498.9 KFO98407.1 - 6.8 5.5 21.6 1.4 7.8 3.4 3.4 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 Pkinase PF00069.25 KFO98408.1 - 6.6e-80 268.3 0.0 1e-79 267.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO98408.1 - 1.1e-35 123.2 0.0 1.4e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFO98408.1 - 1.7e-10 40.7 0.0 6.4e-09 35.5 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KFO98408.1 - 3.6e-05 23.8 0.0 0.16 11.8 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KFO98408.1 - 5.4e-05 22.6 0.0 9.6e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KFO98408.1 - 0.00031 20.5 0.1 0.46 10.1 0.1 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KFO98408.1 - 0.00033 19.6 0.0 0.0012 17.8 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 KFO98408.1 - 0.00095 18.8 0.1 0.0017 18.0 0.1 1.4 1 0 0 1 1 1 1 RIO1 family CsgA PF17334.2 KFO98408.1 - 0.02 15.6 1.0 0.33 11.7 0.0 2.8 3 0 0 3 3 3 0 Minor curli fiber component A DcpS_C PF11969.8 KFO98408.1 - 0.045 14.2 0.1 1.9 9.0 0.0 2.5 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding YrbL-PhoP_reg PF10707.9 KFO98408.1 - 0.14 11.7 0.1 0.32 10.5 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Sema PF01403.19 KFO98409.1 - 6.7e-63 213.0 0.0 8e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 Sema domain Plexin_cytopl PF08337.12 KFO98410.1 - 1.8e-250 832.3 0.1 2.2e-250 832.1 0.1 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.24 KFO98410.1 - 1.7e-39 133.8 9.7 1.2e-10 41.3 0.0 5.8 6 0 0 6 6 6 4 IPT/TIG domain TIG_2 PF18020.1 KFO98410.1 - 1.3e-31 109.1 0.0 7.6e-31 106.6 0.0 2.4 2 0 0 2 2 2 1 TIG domain found in plexin TIG_plexin PF17960.1 KFO98410.1 - 1.7e-24 85.6 5.4 2.9e-22 78.5 0.0 4.6 6 0 0 6 6 6 2 TIG domain PSI PF01437.25 KFO98410.1 - 3.9e-20 72.1 58.8 3.5e-10 40.3 13.9 3.5 3 0 0 3 3 3 3 Plexin repeat RasGAP PF00616.19 KFO98410.1 - 0.00031 20.5 1.0 0.1 12.3 1.5 2.6 2 1 0 2 2 2 2 GTPase-activator protein for Ras-like GTPase PSI_integrin PF17205.3 KFO98410.1 - 0.0017 18.1 45.6 0.0038 16.9 8.7 3.7 3 0 0 3 3 3 2 Integrin plexin domain RhoGEF PF00621.20 KFO98411.1 - 2.9e-39 135.2 5.8 2.9e-39 135.2 5.8 3.5 2 1 2 4 4 4 1 RhoGEF domain PH PF00169.29 KFO98411.1 - 2.8e-09 37.4 0.1 6.8e-09 36.2 0.1 1.7 1 0 0 1 1 1 1 PH domain Spectrin PF00435.21 KFO98411.1 - 3.6e-09 37.1 14.3 3.3e-05 24.3 0.0 4.7 3 1 1 4 4 4 2 Spectrin repeat CRAL_TRIO_2 PF13716.6 KFO98411.1 - 4.8e-07 30.0 0.0 1.4e-06 28.5 0.0 1.9 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PH_10 PF15411.6 KFO98411.1 - 0.013 15.8 0.0 0.036 14.3 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain ARL2_Bind_BART PF11527.8 KFO98411.1 - 1.7 8.8 8.0 4.2 7.5 1.1 3.2 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART Snapin_Pallidin PF14712.6 KFO98411.1 - 3.7 8.0 10.5 2 8.9 0.4 3.5 3 0 0 3 3 3 0 Snapin/Pallidin PhoLip_ATPase_C PF16212.5 KFO98412.1 - 1.4e-80 270.7 32.8 1.4e-80 270.7 32.8 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFO98412.1 - 6.3e-22 77.0 0.2 6.3e-22 77.0 0.2 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 KFO98412.1 - 6.4e-11 42.1 0.5 3.2e-10 39.8 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KFO98412.1 - 1.1e-10 41.4 0.1 2.2e-09 37.2 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFO98412.1 - 1.6e-10 41.6 0.2 6.8e-05 23.3 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFO98412.1 - 0.00066 19.5 0.0 0.083 12.6 0.0 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFO98412.1 - 0.01 16.3 0.0 0.81 10.1 0.1 2.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase GCP_C_terminal PF04130.13 KFO98413.1 - 2.9e-83 279.9 10.9 2.9e-83 279.9 10.9 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KFO98413.1 - 1.2e-81 274.7 0.6 2.7e-81 273.5 0.6 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF3519 PF12033.8 KFO98413.1 - 0.12 12.8 0.3 0.77 10.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3519) AAA_33 PF13671.6 KFO98414.1 - 3.3e-22 79.2 0.0 4.9e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFO98414.1 - 0.00012 21.4 0.0 0.00037 19.8 0.0 1.6 1 1 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 KFO98414.1 - 0.0006 20.4 0.0 0.0015 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain SPRY PF00622.28 KFO98414.1 - 0.00063 19.9 0.0 0.0065 16.6 0.0 2.3 2 0 0 2 2 2 1 SPRY domain AAA_17 PF13207.6 KFO98414.1 - 0.0015 18.9 0.0 0.003 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain 7tm_4 PF13853.6 KFO98415.1 - 1.2e-22 80.9 5.1 1.5e-22 80.7 5.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO98415.1 - 2.1e-05 24.0 4.8 2.5e-05 23.7 4.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dymeclin PF09742.9 KFO98416.1 - 1.1e-09 37.4 0.1 1.1e-09 37.4 0.1 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein COesterase PF00135.28 KFO98417.1 - 2.7e-57 194.8 0.0 3e-57 194.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Clat_adaptor_s PF01217.20 KFO98418.1 - 1.2e-37 129.1 0.3 1.3e-37 128.9 0.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CNOT1_HEAT PF16418.5 KFO98418.1 - 0.042 13.9 0.1 0.057 13.5 0.1 1.2 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 HEAT repeat CortBP2 PF09727.9 KFO98419.1 - 1.4e-50 171.9 22.9 1.4e-50 171.9 22.9 7.1 1 1 6 7 7 7 2 Cortactin-binding protein-2 DUF768 PF05589.11 KFO98419.1 - 1.2 9.2 3.3 25 5.0 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF768) T2SSF PF00482.23 KFO98419.1 - 1.9 8.5 4.0 13 5.8 0.1 3.9 4 0 0 4 4 4 0 Type II secretion system (T2SS), protein F CDC50 PF03381.15 KFO98420.1 - 1.7e-93 313.2 0.3 2.1e-93 312.9 0.3 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family fn3 PF00041.21 KFO98421.1 - 3.8e-251 812.3 83.9 1.2e-16 60.8 1.1 18.3 18 0 0 18 18 18 18 Fibronectin type III domain VWA PF00092.28 KFO98421.1 - 1e-204 673.9 12.4 1.5e-51 175.2 0.0 4.4 4 0 0 4 4 4 4 von Willebrand factor type A domain VWA_2 PF13519.6 KFO98421.1 - 1e-61 206.2 0.0 9.4e-15 55.2 0.0 5.0 5 0 0 5 5 5 4 von Willebrand factor type A domain Collagen PF01391.18 KFO98421.1 - 8.5e-34 115.1 174.4 3.5e-08 33.1 31.2 5.5 2 2 3 5 5 5 5 Collagen triple helix repeat (20 copies) Pur_ac_phosph_N PF16656.5 KFO98421.1 - 1.2e-28 99.5 49.9 0.0053 17.3 0.4 18.5 14 4 1 15 15 15 9 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFO98421.1 - 3.3e-24 85.2 0.0 0.49 10.8 0.0 15.1 17 0 0 17 17 16 2 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 KFO98421.1 - 1.2e-20 73.6 7.7 1.9 9.0 0.0 15.2 16 0 0 16 16 16 2 Uncharacterised conserved protein (DUF2369) DUF4998 PF16389.5 KFO98421.1 - 1e-13 51.3 0.5 3 7.4 0.0 11.6 13 2 1 15 15 15 2 Domain of unknown function Copine PF07002.16 KFO98421.1 - 0.0017 17.8 0.0 0.0044 16.5 0.0 1.6 1 0 0 1 1 1 1 Copine CBM_4_9 PF02018.17 KFO98421.1 - 0.0056 16.9 3.8 3.5 7.9 0.1 4.7 5 0 0 5 5 4 1 Carbohydrate binding domain Toxin_R_bind_N PF07953.12 KFO98421.1 - 0.012 15.3 0.2 0.021 14.5 0.2 1.3 1 0 0 1 1 1 0 Clostridium neurotoxin, N-terminal receptor binding Big_4 PF07532.11 KFO98421.1 - 0.086 12.6 8.7 11 5.8 0.2 7.2 6 0 0 6 6 6 0 Bacterial Ig-like domain (group 4) ASH PF15780.5 KFO98421.1 - 0.15 12.3 0.5 45 4.3 0.1 4.9 4 0 0 4 4 3 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin ThiI PF02568.14 KFO98421.1 - 0.19 11.3 0.0 0.46 10.0 0.0 1.5 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) DJ-1_PfpI PF01965.24 KFO98421.1 - 0.64 9.8 6.1 50 3.6 0.0 4.6 5 0 0 5 5 5 0 DJ-1/PfpI family DUF5412 PF17428.2 KFO98421.1 - 3.1 7.7 4.2 54 3.7 0.0 4.7 5 0 0 5 5 5 0 Family of unknown function (DUF5412) TED_complement PF07678.14 KFO98422.1 - 2.3e-98 329.1 0.0 5.9e-98 327.7 0.0 1.7 2 0 0 2 2 2 1 A-macroglobulin TED domain A2M PF00207.22 KFO98422.1 - 5.4e-30 103.1 0.9 4e-29 100.3 0.9 2.7 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_BRD PF07703.14 KFO98422.1 - 5.8e-26 91.5 13.3 3.9e-24 85.6 0.4 4.6 6 0 0 6 6 6 2 Alpha-2-macroglobulin bait region domain A2M_recep PF07677.14 KFO98422.1 - 1.4e-22 80.2 0.1 4.4e-22 78.6 0.1 2.0 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain MG3 PF17791.1 KFO98422.1 - 7.4e-18 64.6 0.1 4.1e-17 62.2 0.2 2.3 2 0 0 2 2 2 1 Macroglobulin domain MG3 MG2 PF01835.19 KFO98422.1 - 7.1e-16 58.4 0.1 3.4e-14 53.1 0.0 3.6 4 0 0 4 4 4 1 MG2 domain DP-EP PF08985.11 KFO98422.1 - 0.86 9.8 6.0 9.5 6.4 0.1 3.4 3 0 0 3 3 3 0 DP-EP family MFS_1 PF07690.16 KFO98423.1 - 2e-58 198.0 32.1 3e-57 194.1 24.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFO98423.1 - 4e-07 29.3 24.6 1.7e-05 23.9 24.6 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter GTP_EFTU PF00009.27 KFO98424.1 - 1.8e-54 184.2 0.0 2.6e-54 183.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFO98424.1 - 2.3e-40 137.4 0.0 5e-40 136.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KFO98424.1 - 4.1e-15 55.9 1.9 6.3e-15 55.3 0.6 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFO98424.1 - 0.00031 20.8 0.2 0.0083 16.2 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KFO98424.1 - 0.017 15.0 1.2 0.031 14.2 0.2 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Dynamin_N PF00350.23 KFO98424.1 - 0.079 13.0 0.1 17 5.4 0.1 2.4 2 0 0 2 2 2 0 Dynamin family G-alpha PF00503.20 KFO98424.1 - 0.24 10.5 0.2 0.7 9.0 0.1 1.8 2 0 0 2 2 2 0 G-protein alpha subunit Pkinase PF00069.25 KFO98425.1 - 2.3e-47 161.6 0.0 2.6e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO98425.1 - 2.5e-21 76.1 0.0 3.1e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFO98425.1 - 0.0068 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YukC PF10140.9 KFO98425.1 - 0.087 11.6 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 KFO98425.1 - 0.1 12.5 0.8 0.18 11.7 0.1 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KFO98425.1 - 0.18 11.2 0.1 0.26 10.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KFO98425.1 - 0.29 10.0 0.1 0.41 9.6 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase 6PF2K PF01591.18 KFO98426.1 - 5.6e-30 104.3 0.1 6.3e-30 104.1 0.1 1.0 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KFO98426.1 - 0.0018 18.0 0.1 0.0027 17.4 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_S6 PF01250.17 KFO98426.1 - 0.13 12.5 0.0 0.2 12.0 0.0 1.3 1 1 0 1 1 1 0 Ribosomal protein S6 RVT_1 PF00078.27 KFO98427.1 - 0.0058 16.2 0.0 0.0096 15.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFO98428.1 - 0.0003 20.4 0.0 0.00047 19.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cadherin PF00028.17 KFO98430.1 - 1.6e-103 339.4 1.5 1.2e-22 80.1 0.0 7.3 7 0 0 7 7 7 7 Cadherin domain Protocadherin PF08374.11 KFO98430.1 - 6.4e-71 238.8 0.9 9.9e-71 238.2 0.9 1.3 1 0 0 1 1 1 1 Protocadherin Cadherin_2 PF08266.12 KFO98430.1 - 8.1e-14 51.2 0.0 4.1e-06 26.6 0.0 4.6 4 0 0 4 4 4 2 Cadherin-like TMEM154 PF15102.6 KFO98430.1 - 0.001 19.0 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family Mid2 PF04478.12 KFO98430.1 - 0.0021 17.9 0.1 0.0054 16.6 0.1 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor LYRIC PF15686.5 KFO98430.1 - 0.041 13.4 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Amnionless PF14828.6 KFO98430.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Amnionless Adeno_E3_CR2 PF02439.15 KFO98430.1 - 0.16 11.7 1.6 0.4 10.5 1.6 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF3827 PF12877.7 KFO98430.1 - 0.25 9.7 2.1 0.2 10.0 0.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3827) He_PIG PF05345.12 KFO98430.1 - 1.6 9.0 13.6 1.4 9.2 0.3 5.4 5 1 1 6 6 6 0 Putative Ig domain SOAR PF16533.5 KFO98431.1 - 1.2e-40 137.5 3.9 1.2e-40 137.5 3.9 3.0 2 1 1 3 3 3 1 STIM1 Orai1-activating region SAM_2 PF07647.17 KFO98431.1 - 4.6e-12 45.9 0.1 1.3e-11 44.5 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFO98431.1 - 5e-07 30.1 0.1 1.6e-06 28.5 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) ESSS PF10183.9 KFO98431.1 - 0.32 11.2 0.0 0.32 11.2 0.0 2.9 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF4446 PF14584.6 KFO98431.1 - 0.37 10.8 4.7 0.092 12.7 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Orbi_NS3 PF01616.16 KFO98431.1 - 1.7 8.3 4.7 2.1 8.0 0.1 2.6 3 0 0 3 3 3 0 Orbivirus NS3 RabGAP-TBC PF00566.18 KFO98432.1 - 7.6e-15 55.1 7.1 1.6e-12 47.6 2.5 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain 7tm_1 PF00001.21 KFO98433.1 - 3.7e-63 213.3 14.7 5e-63 212.9 14.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CholecysA-Rec_N PF09193.10 KFO98433.1 - 5e-30 103.2 0.5 1.2e-29 102.0 0.5 1.7 1 0 0 1 1 1 1 Cholecystokinin A receptor, N-terminal 7tm_4 PF13853.6 KFO98433.1 - 4.3e-10 39.8 10.2 4.3e-10 39.8 10.2 1.8 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KFO98433.1 - 5.8e-08 32.4 23.6 3.9e-07 29.7 23.6 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Brr6_like_C_C PF10104.9 KFO98433.1 - 0.28 10.9 0.0 0.28 10.9 0.0 3.0 3 0 0 3 3 3 0 Di-sulfide bridge nucleocytoplasmic transport domain BTD PF09270.10 KFO98434.1 - 1.4e-75 252.7 0.0 2.2e-75 252.0 0.0 1.4 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.11 KFO98434.1 - 6e-50 169.8 0.7 6e-50 169.8 0.7 1.8 2 0 0 2 2 2 1 LAG1, DNA binding TIG PF01833.24 KFO98434.1 - 4.2e-05 23.5 1.2 0.00042 20.3 0.0 2.5 2 0 0 2 2 2 1 IPT/TIG domain RHD_dimer PF16179.5 KFO98434.1 - 0.017 15.1 0.0 0.071 13.1 0.0 2.2 1 1 0 1 1 1 0 Rel homology dimerisation domain Sel1 PF08238.12 KFO98436.1 - 1.9e-17 63.3 32.7 0.00017 22.1 1.1 8.6 8 0 0 8 8 8 6 Sel1 repeat Na_Pi_cotrans PF02690.15 KFO98437.1 - 2.8e-38 131.2 26.0 5.8e-24 84.8 7.3 2.7 2 1 0 2 2 2 2 Na+/Pi-cotransporter YbhQ PF11076.8 KFO98437.1 - 0.24 11.4 2.9 1.5 8.9 0.1 2.7 2 0 0 2 2 2 0 Putative inner membrane protein YbhQ PI3_PI4_kinase PF00454.27 KFO98438.1 - 1.2e-68 231.6 0.0 1.5e-68 231.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SepSecS PF05889.13 KFO98439.1 - 4.9e-179 595.0 0.0 5.6e-179 594.8 0.0 1.0 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 KFO98439.1 - 2e-05 24.0 0.0 2.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 KFO98439.1 - 0.037 12.8 0.1 0.63 8.7 0.0 2.2 1 1 1 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain EPTP PF03736.17 KFO98440.1 - 2.8e-72 238.5 22.4 1.5e-13 50.5 0.1 7.3 7 0 0 7 7 7 7 EPTP domain LRR_8 PF13855.6 KFO98440.1 - 1.8e-24 85.3 9.7 6.9e-14 51.4 2.0 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFO98440.1 - 1.7e-08 34.6 3.1 0.00048 20.5 0.6 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFO98440.1 - 2.7e-08 33.9 0.1 1.6e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFO98440.1 - 0.0013 18.3 0.1 0.16 11.5 0.0 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFO98440.1 - 0.0054 17.1 5.7 42 5.2 0.0 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat DUF2353 PF09789.9 KFO98441.1 - 1.1e-91 307.5 21.4 1.6e-91 306.9 21.4 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) CALCOCO1 PF07888.11 KFO98441.1 - 0.001 18.0 15.2 0.001 18.0 15.2 1.9 1 1 1 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like Csm1_N PF18504.1 KFO98441.1 - 0.0078 16.5 22.5 0.026 14.9 0.6 5.4 5 0 0 5 5 5 1 Csm1 N-terminal domain Baculo_VP39 PF04501.12 KFO98441.1 - 0.02 14.4 0.5 0.032 13.7 0.5 1.2 1 0 0 1 1 1 0 Baculovirus major capsid protein VP39 KLRAQ PF10205.9 KFO98441.1 - 0.042 14.1 12.3 2.8 8.2 5.3 4.0 3 1 0 3 3 3 0 Predicted coiled-coil domain-containing protein TSC22 PF01166.18 KFO98441.1 - 0.049 14.0 0.1 0.049 14.0 0.1 5.2 5 0 0 5 5 5 0 TSC-22/dip/bun family CorA PF01544.18 KFO98441.1 - 0.12 11.7 15.1 0.019 14.3 7.3 2.5 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein HAP1_N PF04849.13 KFO98441.1 - 0.13 11.5 24.9 0.025 13.8 10.3 3.7 3 1 1 4 4 4 0 HAP1 N-terminal conserved region DUF4482 PF14818.6 KFO98441.1 - 0.19 12.6 20.4 1.1 10.1 1.5 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4482) DivIVA PF05103.13 KFO98441.1 - 0.2 11.7 15.3 0.2 11.7 4.1 3.2 3 0 0 3 3 3 0 DivIVA protein LPP PF04728.13 KFO98441.1 - 0.24 11.8 7.4 12 6.4 0.1 4.4 4 0 0 4 4 4 0 Lipoprotein leucine-zipper THP2 PF09432.10 KFO98441.1 - 0.27 11.3 4.9 1.2 9.2 4.9 2.1 1 1 0 1 1 1 0 Tho complex subunit THP2 HrpB7 PF09486.10 KFO98441.1 - 0.34 11.3 10.5 0.066 13.6 4.7 2.5 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) GAS PF13851.6 KFO98441.1 - 0.6 9.4 29.0 0.061 12.7 3.6 4.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Tugs PF17840.1 KFO98441.1 - 1.2 9.4 6.8 11 6.3 0.7 3.2 3 0 0 3 3 2 0 Tethering Ubl4a to BAGS domain DUF4164 PF13747.6 KFO98441.1 - 1.3 9.4 15.4 0.97 9.8 4.1 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4164) DUF3461 PF11944.8 KFO98441.1 - 1.4 9.1 5.9 20 5.4 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3461) Lebercilin PF15619.6 KFO98441.1 - 1.4 8.5 28.3 4.5 6.9 11.9 4.3 2 1 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Syntaxin-6_N PF09177.11 KFO98441.1 - 1.6 9.3 12.7 10 6.7 0.9 4.4 2 1 2 4 4 4 0 Syntaxin 6, N-terminal DUF2959 PF11172.8 KFO98441.1 - 1.7 8.7 8.5 0.84 9.7 4.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2959) Spc29 PF17082.5 KFO98441.1 - 2.2 8.1 11.2 3.5 7.4 0.6 3.3 1 1 2 4 4 4 0 Spindle Pole Component 29 Chibby PF14645.6 KFO98441.1 - 2.2 8.7 7.2 4.9 7.6 2.4 2.9 2 1 0 2 2 2 0 Chibby family Cob_adeno_trans PF01923.18 KFO98441.1 - 2.6 8.2 9.1 5.3 7.1 0.1 3.8 2 2 2 4 4 4 0 Cobalamin adenosyltransferase Tho2 PF11262.8 KFO98441.1 - 2.8 7.1 7.4 0.18 11.0 1.5 2.0 2 1 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 TPR_MLP1_2 PF07926.12 KFO98441.1 - 2.9 8.0 31.1 0.19 11.8 0.9 4.9 5 1 0 5 5 4 0 TPR/MLP1/MLP2-like protein COG2 PF06148.11 KFO98441.1 - 3.2 7.9 9.3 3.3 7.8 0.4 3.2 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 CENP-F_leu_zip PF10473.9 KFO98441.1 - 4.4 7.3 31.7 5 7.1 4.8 4.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.22 KFO98441.1 - 4.9 7.4 21.5 2 8.7 1.7 4.4 3 1 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain FapA PF03961.13 KFO98441.1 - 5.3 5.5 17.3 0.18 10.3 1.5 2.9 1 1 0 3 3 3 0 Flagellar Assembly Protein A GIT_CC PF16559.5 KFO98441.1 - 6.1 6.8 25.6 0.36 10.7 1.1 4.8 5 0 0 5 5 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Phlebovirus_NSM PF07246.11 KFO98441.1 - 6.5 6.0 9.2 9.4 5.5 0.9 2.8 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M FlaC_arch PF05377.11 KFO98441.1 - 9.3 6.7 13.4 28 5.2 0.1 4.9 5 1 0 5 5 4 0 Flagella accessory protein C (FlaC) Sod_Cu PF00080.20 KFO98442.1 - 2.4e-32 112.0 0.0 3.1e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HA2 PF04408.23 KFO98443.1 - 7.5e-24 84.1 0.2 1.6e-23 83.1 0.2 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFO98443.1 - 2e-17 63.3 0.1 4.7e-17 62.1 0.1 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFO98443.1 - 1e-12 48.3 0.0 2.5e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFO98443.1 - 4.8e-07 29.7 0.0 1.2e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KFO98443.1 - 0.00011 22.5 0.0 0.00028 21.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFO98443.1 - 0.00049 20.4 0.8 0.0081 16.4 0.8 2.7 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 KFO98443.1 - 0.0019 17.8 0.0 0.0062 16.2 0.0 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.15 KFO98443.1 - 0.0026 17.8 0.0 0.36 10.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 KFO98443.1 - 0.01 15.4 0.0 0.026 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFO98443.1 - 0.01 15.5 0.0 0.023 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 KFO98443.1 - 0.014 15.4 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_29 PF13555.6 KFO98443.1 - 0.037 13.8 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain HTH_IclR PF09339.10 KFO98443.1 - 0.1 12.4 0.1 0.32 10.8 0.1 1.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain IstB_IS21 PF01695.17 KFO98443.1 - 0.11 12.3 0.0 17 5.1 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.6 KFO98443.1 - 0.18 12.3 0.0 0.43 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain RRM_1 PF00076.22 KFO98444.1 - 4.1e-07 29.7 0.0 8.2e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Yae1_N PF09811.9 KFO98445.1 - 3e-10 39.6 35.2 0.027 14.2 3.9 3.8 2 1 0 2 2 2 2 Essential protein Yae1, N terminal Amino_oxidase PF01593.24 KFO98446.1 - 1.7e-05 24.4 0.0 9.2e-05 21.9 0.0 2.0 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase Cofilin_ADF PF00241.20 KFO98447.1 - 2.6e-14 53.1 0.0 3.5e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_9 PF14604.6 KFO98447.1 - 6.8e-09 35.4 0.0 1.4e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFO98447.1 - 3e-07 29.9 0.1 7.8e-07 28.6 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFO98447.1 - 0.00016 21.3 0.0 0.00038 20.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_M14 PF00246.24 KFO98448.1 - 3.4e-69 233.9 0.0 4.6e-69 233.4 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase F5_F8_type_C PF00754.25 KFO98448.1 - 1.3e-24 86.8 0.1 2e-24 86.1 0.1 1.4 1 0 0 1 1 1 1 F5/8 type C domain CarboxypepD_reg PF13620.6 KFO98448.1 - 5.2e-13 49.1 0.0 8.8e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KFO98448.1 - 0.00018 21.5 0.0 0.00034 20.6 0.0 1.5 1 0 0 1 1 1 1 CarboxypepD_reg-like domain DNA_pol_E_B PF04042.16 KFO98449.1 - 6.2e-41 140.1 0.4 1.1e-40 139.3 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KFO98449.1 - 8e-37 126.3 0.0 1.5e-36 125.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain CS PF04969.16 KFO98451.1 - 1.8e-17 64.1 0.6 4.9e-17 62.7 0.2 2.0 2 0 0 2 2 2 1 CS domain DUF1737 PF08410.10 KFO98451.1 - 0.16 11.9 0.1 0.36 10.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) PHO4 PF01384.20 KFO98452.1 - 1.1e-143 478.4 1.0 1.4e-143 478.0 1.0 1.1 1 0 0 1 1 1 1 Phosphate transporter family 5_nucleotid PF05761.14 KFO98453.1 - 1.3e-169 565.0 0.1 1.4e-169 564.8 0.1 1.0 1 0 0 1 1 1 1 5' nucleotidase family E1_dh PF00676.20 KFO98454.1 - 6.5e-99 330.7 0.0 8.9e-99 330.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 KFO98454.1 - 1.1e-67 227.1 0.0 1.7e-67 226.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 KFO98454.1 - 7.2e-58 194.6 0.0 1.2e-57 193.9 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KFO98454.1 - 2.5e-19 68.6 3.9 3.9e-19 67.9 1.0 2.3 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus GGA_N-GAT PF18308.1 KFO98454.1 - 0.085 12.5 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 GGA N-GAT domain R2K_2 PF18299.1 KFO98454.1 - 0.16 11.8 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 zf-MIZ PF02891.20 KFO98455.1 - 4.2e-23 80.8 4.4 4.2e-23 80.8 4.4 2.3 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KFO98455.1 - 7e-06 25.8 1.0 7e-06 25.8 1.0 2.4 3 0 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit Pro_isomerase PF00160.21 KFO98456.1 - 1.2e-39 136.2 0.2 1.3e-39 136.0 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Laminin_EGF PF00053.24 KFO98459.1 - 1.1e-20 73.5 149.5 6.4e-05 23.0 5.6 10.0 3 2 7 10 10 10 9 Laminin EGF domain EGF_2 PF07974.13 KFO98459.1 - 2e-05 24.8 21.3 7.9e-05 22.9 6.3 15.7 10 6 4 14 14 14 7 EGF-like domain IP_trans PF02121.18 KFO98460.1 - 2.7e-116 387.4 1.8 3.3e-116 387.1 1.8 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein DUF5595 PF18077.1 KFO98460.1 - 0.13 12.4 2.3 0.25 11.4 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) SKICH PF17751.1 KFO98461.1 - 2.4e-30 105.1 0.2 5e-30 104.1 0.2 1.6 1 0 0 1 1 1 1 SKICH domain Exo_endo_phos PF03372.23 KFO98461.1 - 1.8e-11 44.0 0.0 2.7e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Myosin_head PF00063.21 KFO98462.1 - 3.6e-251 835.2 5.6 4.7e-251 834.8 5.6 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KFO98462.1 - 5.8e-32 110.9 1.7 1.3e-31 109.8 1.7 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding IQ PF00612.27 KFO98462.1 - 0.00064 19.3 16.3 0.0024 17.5 1.0 4.0 4 0 0 4 4 4 2 IQ calmodulin-binding motif AAA_22 PF13401.6 KFO98462.1 - 0.0086 16.4 0.1 0.065 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFO98462.1 - 0.021 15.2 0.0 0.08 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 KFO98462.1 - 0.028 13.7 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 KFO98462.1 - 0.079 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE 14-3-3 PF00244.20 KFO98463.1 - 9.4e-101 335.9 0.8 1e-100 335.8 0.8 1.0 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 KFO98463.1 - 0.057 11.8 0.5 0.089 11.2 0.5 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 SH3_2 PF07653.17 KFO98464.1 - 1.6e-24 85.3 2.8 2.9e-11 42.9 0.0 3.1 3 1 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 KFO98464.1 - 1.7e-17 62.7 5.0 3.7e-15 55.3 0.2 2.7 3 0 0 3 3 3 2 SH3 domain SH2 PF00017.24 KFO98464.1 - 8.5e-17 61.0 0.0 1.9e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 KFO98464.1 - 1.8e-13 50.1 0.2 4.3e-09 36.1 0.1 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH3_10 PF17902.1 KFO98464.1 - 0.074 13.1 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 SH3 domain DUF3804 PF12707.7 KFO98464.1 - 0.19 11.5 0.0 0.7 9.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3804) NCBP3 PF10309.9 KFO98465.1 - 8.3e-21 73.6 0.1 2e-20 72.4 0.1 1.7 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 KFO98465.1 - 0.001 19.0 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 RNA binding domain NAD_binding_1 PF00175.21 KFO98465.1 - 1.1 9.9 2.9 2.2 8.9 0.1 2.9 3 1 1 4 4 4 0 Oxidoreductase NAD-binding domain T2SSK PF03934.13 KFO98466.1 - 0.00022 20.7 0.4 0.0011 18.4 0.1 1.9 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein K LRR_4 PF12799.7 KFO98466.1 - 0.003 17.9 0.9 0.018 15.5 0.6 2.4 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFO98466.1 - 0.074 13.1 0.7 0.45 10.7 0.2 2.5 2 0 0 2 2 2 0 Leucine Rich repeat TMEM219 PF14940.6 KFO98467.1 - 3e-87 292.1 0.5 4e-87 291.7 0.5 1.1 1 0 0 1 1 1 1 Transmembrane 219 Omp28 PF11551.8 KFO98467.1 - 0.044 13.6 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Outer membrane protein Omp28 VPS9 PF02204.18 KFO98468.1 - 1.6e-29 102.1 0.0 5.3e-29 100.5 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KFO98468.1 - 1.1e-20 73.7 1.8 3.3e-20 72.2 1.8 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) zf-A20 PF01754.16 KFO98468.1 - 4.2e-12 45.8 6.8 9e-12 44.7 6.8 1.6 1 0 0 1 1 1 1 A20-like zinc finger Syntaxin PF00804.25 KFO98468.1 - 0.0058 16.3 9.4 0.19 11.4 3.2 2.6 2 1 0 2 2 2 2 Syntaxin SSTK-IP PF15836.5 KFO98468.1 - 0.05 13.7 0.2 0.24 11.6 0.0 2.0 2 0 0 2 2 2 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein Flavodoxin_NdrI PF07972.11 KFO98468.1 - 0.12 12.5 0.8 0.72 10.0 0.1 2.4 1 1 1 2 2 2 0 NrdI Flavodoxin like YtxH PF12732.7 KFO98468.1 - 0.79 10.3 3.1 23 5.6 0.2 2.9 2 0 0 2 2 2 0 YtxH-like protein GIT1_C PF12205.8 KFO98468.1 - 1.4 9.0 7.7 6.4 6.9 0.2 3.8 3 2 0 4 4 4 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF2116 PF09889.9 KFO98468.1 - 7.3 6.7 5.8 6.9 6.7 2.0 2.7 2 1 1 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) BTB_2 PF02214.22 KFO98469.1 - 2.5e-20 72.6 0.1 1.4e-19 70.2 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 KFO98469.1 - 0.0054 16.8 0.0 0.0091 16.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Sulfotransfer_3 PF13469.6 KFO98470.1 - 2.5e-54 185.0 0.0 3.8e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KFO98470.1 - 2.1e-08 34.0 0.1 2e-07 30.8 0.1 2.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 KFO98470.1 - 0.0016 18.3 0.0 0.0084 16.0 0.1 2.2 1 1 1 2 2 2 1 Sulfotransferase domain RNA_pol_Rpb4 PF03874.16 KFO98471.1 - 6.8e-10 39.3 0.3 8.2e-10 39.1 0.3 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 Lyase_1 PF00206.20 KFO98472.1 - 1.4e-104 349.9 0.0 4e-104 348.4 0.0 1.7 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.6 KFO98472.1 - 8.6e-19 68.1 0.0 4.1e-18 65.9 0.0 2.3 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal Get5_bdg PF16843.5 KFO98472.1 - 0.11 12.0 0.4 1.1 8.8 0.0 2.5 2 0 0 2 2 2 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein Bacillus_HBL PF05791.11 KFO98472.1 - 0.24 11.2 1.8 1.1 9.0 0.0 2.5 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) APG17 PF04108.12 KFO98472.1 - 0.35 9.9 5.4 5.6 6.0 0.4 2.9 3 0 0 3 3 3 0 Autophagy protein Apg17 Glyco_hydro_2_C PF02836.17 KFO98473.1 - 9.2e-107 356.6 0.0 1.2e-106 356.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KFO98473.1 - 5.5e-18 65.4 0.1 1e-17 64.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KFO98473.1 - 6.2e-05 23.6 0.3 0.00025 21.7 0.3 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 VKOR PF07884.14 KFO98474.1 - 1.1e-15 57.9 13.6 1.3e-15 57.7 13.6 1.1 1 0 0 1 1 1 1 Vitamin K epoxide reductase family G3P_acyltransf PF02660.15 KFO98474.1 - 0.74 9.9 9.2 0.93 9.5 9.2 1.1 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase Tmemb_55A PF09788.9 KFO98474.1 - 1.2 8.2 5.3 1.4 7.9 5.3 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A SPC25 PF06703.11 KFO98474.1 - 6.6 6.5 11.9 6.8 6.5 10.7 1.6 1 1 1 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) CHCH PF06747.13 KFO98475.1 - 2.2e-06 27.7 7.8 3.2e-06 27.1 7.8 1.3 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.9 KFO98475.1 - 5.4 7.0 23.8 0.69 9.9 9.9 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Pkinase PF00069.25 KFO98476.1 - 2.2e-78 263.2 0.0 2.7e-78 263.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO98476.1 - 5.8e-33 114.3 0.0 7.3e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFO98476.1 - 6.3e-12 45.4 0.0 2.9e-10 40.0 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 KFO98476.1 - 6.1e-08 32.3 0.3 4.2e-07 29.5 0.1 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFO98476.1 - 5.7e-06 25.4 0.2 0.00022 20.1 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 KFO98476.1 - 2.2e-05 23.6 0.6 3.5e-05 22.9 0.6 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KFO98476.1 - 6e-05 22.7 0.2 0.00011 21.8 0.2 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KFO98476.1 - 0.00027 20.9 0.1 0.36 10.7 0.3 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family FTA2 PF13095.6 KFO98476.1 - 0.0024 17.5 0.1 0.41 10.3 0.1 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 CdiA_C PF18451.1 KFO98476.1 - 0.0037 17.4 0.1 0.015 15.5 0.1 2.0 2 0 0 2 2 2 1 Contact-dependent growth inhibition CdiA C-terminal domain Choline_kinase PF01633.20 KFO98476.1 - 0.0075 15.9 0.2 0.014 15.0 0.2 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Bac_DNA_binding PF00216.21 KFO98476.1 - 0.093 12.9 0.7 0.23 11.7 0.1 2.0 2 0 0 2 2 2 0 Bacterial DNA-binding protein YrbL-PhoP_reg PF10707.9 KFO98476.1 - 0.11 12.0 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FGE-sulfatase PF03781.16 KFO98477.1 - 2.9e-79 266.3 4.3 3.4e-79 266.1 4.3 1.0 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Cpn60_TCP1 PF00118.24 KFO98478.1 - 8.5e-107 357.8 5.7 2.8e-69 234.0 0.1 2.0 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family Hydrolase PF00702.26 KFO98479.1 - 2.9e-18 66.9 0.0 4.4e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFO98479.1 - 7.6e-13 49.3 0.0 1.3e-12 48.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFO98479.1 - 1.7e-06 28.3 0.0 0.0028 17.8 0.0 2.6 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KFO98479.1 - 5e-06 26.2 0.0 8.9e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.12 KFO98479.1 - 2.8e-05 23.6 0.0 7.3e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 Putative Phosphatase Acid_phosphat_B PF03767.14 KFO98479.1 - 0.0016 18.1 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_3 PF08282.12 KFO98479.1 - 0.0059 16.4 0.0 0.35 10.6 0.0 2.5 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase StbA PF06406.11 KFO98479.1 - 0.014 14.7 0.0 0.045 13.0 0.0 1.8 2 0 0 2 2 2 0 StbA protein Hydrolase_like PF13242.6 KFO98479.1 - 0.048 13.7 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 HAD-hyrolase-like NIPSNAP PF07978.13 KFO98480.1 - 1e-38 131.6 1.1 1.4e-32 111.9 0.2 2.2 2 0 0 2 2 2 2 NIPSNAP Ribosomal_S17 PF00366.20 KFO98481.1 - 2e-19 69.4 0.0 2.9e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 ERM PF00769.19 KFO98482.1 - 1.9e-46 158.9 43.5 1.9e-46 158.9 43.5 2.2 2 0 0 2 2 2 1 Ezrin/radixin/moesin family FERM_M PF00373.18 KFO98482.1 - 8.9e-27 93.8 1.3 8.9e-27 93.8 1.3 2.8 2 1 0 2 2 2 1 FERM central domain FERM_C PF09380.10 KFO98482.1 - 3.6e-22 78.5 0.2 3.6e-22 78.5 0.2 2.6 3 0 0 3 3 3 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KFO98482.1 - 6.3e-11 42.1 0.3 3.5e-10 39.7 0.3 2.3 1 0 0 1 1 1 1 FERM N-terminal domain IL8 PF00048.20 KFO98483.1 - 1.3e-07 31.7 0.4 1.4e-07 31.6 0.4 1.0 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like IL8 PF00048.20 KFO98484.1 - 5.5e-15 55.3 3.4 6.1e-15 55.1 3.4 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like TMEM132 PF16070.5 KFO98485.1 - 2e-139 464.8 3.8 2.6e-139 464.4 3.8 1.1 1 0 0 1 1 1 1 Transmembrane protein family 132 TMEM132D_C PF15706.5 KFO98485.1 - 1.7e-32 111.0 0.0 3.3e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Alpha_adaptinC2 PF02883.20 KFO98485.1 - 0.14 12.4 0.1 3.5 8.0 0.1 2.8 2 0 0 2 2 2 0 Adaptin C-terminal domain Rad51 PF08423.11 KFO98486.1 - 2.3e-27 95.9 0.0 2.9e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KFO98486.1 - 1.3e-11 44.5 0.0 1.8e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KFO98486.1 - 5.5e-10 39.0 0.3 1.3e-09 37.7 0.3 1.6 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 KFO98486.1 - 2.6e-09 36.8 0.7 2e-08 33.9 0.7 2.0 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA PF00004.29 KFO98486.1 - 0.00063 20.2 0.1 0.0023 18.3 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RecA PF00154.21 KFO98486.1 - 0.00074 19.1 0.1 0.075 12.5 0.0 2.2 2 0 0 2 2 2 1 recA bacterial DNA recombination protein PSY3 PF16836.5 KFO98486.1 - 0.00081 19.0 0.1 0.0013 18.3 0.1 1.2 1 0 0 1 1 1 1 Shu complex component Psy3, DNA-binding description AAA_22 PF13401.6 KFO98486.1 - 0.0036 17.6 0.1 0.0069 16.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFO98486.1 - 0.0062 17.1 0.0 0.013 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KFO98486.1 - 0.013 15.6 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain HHH_5 PF14520.6 KFO98486.1 - 0.014 16.0 0.0 8.4 7.1 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix domain AAA_24 PF13479.6 KFO98486.1 - 0.018 14.7 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KFO98486.1 - 0.021 15.2 0.0 0.038 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain GvpD PF07088.11 KFO98486.1 - 0.052 12.2 0.0 3.6 6.1 0.0 2.2 1 1 1 2 2 2 0 GvpD gas vesicle protein TrwB_AAD_bind PF10412.9 KFO98486.1 - 0.063 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ATPase_2 PF01637.18 KFO98486.1 - 0.09 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KFO98486.1 - 0.091 12.5 0.1 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain PAXNEB PF05625.11 KFO98486.1 - 0.23 10.5 1.6 3.7 6.6 0.2 2.2 2 0 0 2 2 2 0 PAXNEB protein UNC45-central PF11701.8 KFO98487.1 - 4.6e-37 127.3 5.3 8.9e-36 123.2 0.0 4.2 4 1 0 4 4 4 1 Myosin-binding striated muscle assembly central TPR_1 PF00515.28 KFO98487.1 - 5e-13 48.3 12.4 0.00018 21.2 0.7 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFO98487.1 - 9.8e-13 47.2 11.1 0.00078 19.4 0.4 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFO98487.1 - 8.7e-08 31.8 10.2 0.0031 17.6 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat Arm PF00514.23 KFO98487.1 - 1.7e-07 31.0 13.5 0.0042 17.1 0.0 7.1 9 0 0 9 9 8 2 Armadillo/beta-catenin-like repeat TPR_11 PF13414.6 KFO98487.1 - 7.2e-07 28.8 6.2 5.9e-05 22.7 0.6 2.6 2 0 0 2 2 2 2 TPR repeat HEAT_2 PF13646.6 KFO98487.1 - 2e-06 28.1 2.3 0.32 11.4 0.0 5.5 6 0 0 6 6 5 1 HEAT repeats TPR_12 PF13424.6 KFO98487.1 - 2.6e-05 24.4 7.0 0.00048 20.4 3.1 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFO98487.1 - 7.4e-05 23.3 3.0 7.4e-05 23.3 3.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFO98487.1 - 0.00051 20.2 4.0 0.89 10.1 0.1 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFO98487.1 - 0.00064 19.8 0.8 0.021 15.0 0.3 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO98487.1 - 0.0026 17.9 8.5 0.0079 16.4 8.5 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 KFO98487.1 - 0.019 15.0 2.2 4.9 7.2 0.0 3.2 1 1 2 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_14 PF13428.6 KFO98487.1 - 0.026 15.3 1.1 2.4 9.2 0.1 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFO98487.1 - 0.047 14.2 9.2 0.56 10.8 3.1 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFO98487.1 - 0.18 11.9 0.1 0.18 11.9 0.1 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat HEAT_EZ PF13513.6 KFO98487.1 - 0.37 11.3 5.3 19 5.9 0.2 4.9 5 0 0 5 5 5 0 HEAT-like repeat TPR_6 PF13174.6 KFO98487.1 - 0.55 11.0 8.0 2.4 9.0 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat V-ATPase_H_C PF11698.8 KFO98487.1 - 0.68 10.1 3.2 52 4.0 0.0 4.1 4 0 0 4 4 4 0 V-ATPase subunit H Pex2_Pex12 PF04757.14 KFO98488.1 - 2.3e-50 171.3 5.7 2.7e-50 171.0 5.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 KFO98488.1 - 0.00059 19.6 3.2 0.00098 18.9 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFO98488.1 - 0.074 12.9 3.9 0.15 11.9 3.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-piccolo PF05715.13 KFO98488.1 - 0.38 10.9 2.7 0.67 10.1 2.7 1.4 1 0 0 1 1 1 0 Piccolo Zn-finger zf-C3HC4 PF00097.25 KFO98488.1 - 0.95 9.4 4.0 1.7 8.6 4.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFO98488.1 - 4.1 7.8 8.1 22 5.5 8.2 2.0 1 1 1 2 2 2 0 Ring finger domain Adaptin_N PF01602.20 KFO98489.1 - 9.1e-157 522.8 13.2 1.2e-156 522.4 13.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KFO98489.1 - 9.6e-68 227.3 11.6 2.3e-66 222.8 1.5 3.6 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 KFO98489.1 - 1.1e-37 128.5 0.1 3.1e-37 127.1 0.1 1.8 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 KFO98489.1 - 1.5e-22 79.8 4.8 2.3e-06 27.9 0.1 6.5 3 2 5 8 8 8 6 HEAT repeats HEAT PF02985.22 KFO98489.1 - 4.5e-13 48.2 8.8 0.008 16.3 0.1 7.6 7 0 0 7 7 7 3 HEAT repeat Alpha_adaptinC2 PF02883.20 KFO98489.1 - 1.4e-12 47.8 0.4 3e-12 46.8 0.4 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Arm PF00514.23 KFO98489.1 - 4.5e-08 32.9 2.2 0.026 14.5 0.0 5.4 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Cnd3 PF12719.7 KFO98489.1 - 8e-06 25.3 4.5 0.00047 19.4 0.3 2.8 2 1 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain TIP120 PF08623.10 KFO98489.1 - 6.8e-05 22.7 4.6 0.34 10.7 0.0 4.5 4 1 0 4 4 4 1 TATA-binding protein interacting (TIP20) CLASP_N PF12348.8 KFO98489.1 - 7.9e-05 22.3 2.5 0.36 10.3 0.2 4.0 2 2 2 4 4 4 2 CLASP N terminal RTP1_C1 PF10363.9 KFO98489.1 - 0.0002 21.5 4.5 0.68 10.1 0.0 5.0 1 1 2 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm_2 PF04826.13 KFO98489.1 - 0.0019 17.7 1.2 0.039 13.4 0.2 2.6 1 1 1 2 2 2 1 Armadillo-like HEAT_EZ PF13513.6 KFO98489.1 - 0.0068 16.9 5.4 12 6.6 0.0 6.1 7 0 0 7 7 7 0 HEAT-like repeat Sec7_N PF12783.7 KFO98489.1 - 0.0096 15.8 6.3 0.022 14.7 0.2 4.0 4 1 2 6 6 6 1 Guanine nucleotide exchange factor in Golgi transport N-terminal API5 PF05918.11 KFO98489.1 - 0.073 11.9 0.8 0.73 8.6 0.0 2.6 2 1 1 3 3 3 0 Apoptosis inhibitory protein 5 (API5) MOR2-PAG1_C PF14225.6 KFO98489.1 - 0.12 12.2 0.3 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 Cell morphogenesis C-terminal Ras PF00071.22 KFO98490.1 - 3.3e-25 88.6 0.0 6.4e-25 87.6 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFO98490.1 - 4.4e-08 33.4 0.0 4.1e-07 30.2 0.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO98490.1 - 0.00066 19.2 0.0 0.011 15.2 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFO98490.1 - 0.0025 17.9 0.0 0.0035 17.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFO98490.1 - 0.022 15.1 0.0 0.043 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 KFO98490.1 - 0.051 13.8 0.0 0.082 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain TAS2R PF05296.13 KFO98491.1 - 2.6e-57 194.3 36.5 3e-57 194.1 36.5 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) TAS2R PF05296.13 KFO98492.1 - 3e-53 180.9 36.4 3.5e-53 180.7 36.4 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) DUF3742 PF12553.8 KFO98492.1 - 0.08 13.1 1.2 9.6 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) TAS2R PF05296.13 KFO98493.1 - 1.5e-55 188.5 33.2 1.7e-55 188.3 33.2 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) Astacin PF01400.24 KFO98494.1 - 4.5e-68 228.6 0.1 6.8e-68 228.1 0.1 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MAM PF00629.23 KFO98494.1 - 8e-39 133.1 0.1 1.2e-38 132.5 0.1 1.3 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu EGF PF00008.27 KFO98494.1 - 1.3e-08 35.0 5.2 3.8e-08 33.5 5.2 1.9 1 0 0 1 1 1 1 EGF-like domain EGF_CA PF07645.15 KFO98494.1 - 0.25 11.6 6.1 0.69 10.2 6.1 1.7 1 0 0 1 1 1 0 Calcium-binding EGF domain hEGF PF12661.7 KFO98494.1 - 0.66 10.7 8.8 0.17 12.6 5.2 2.0 2 0 0 2 2 2 0 Human growth factor-like EGF 7tm_2 PF00002.24 KFO98495.1 - 3e-32 111.9 20.0 5.4e-32 111.0 20.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) ig PF00047.25 KFO98495.1 - 1e-14 54.5 14.8 2.1e-09 37.4 0.5 3.8 3 0 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.6 KFO98495.1 - 1.3e-14 54.5 13.4 3.8e-09 37.0 0.2 3.7 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFO98495.1 - 1.8e-14 53.5 2.4 3.2e-09 36.7 0.1 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain GPS PF01825.21 KFO98495.1 - 3.3e-14 53.1 3.0 3.3e-14 53.1 3.0 2.4 2 0 0 2 2 1 1 GPCR proteolysis site, GPS, motif Ig_2 PF13895.6 KFO98495.1 - 2.6e-11 43.7 15.5 9.8e-07 29.0 0.3 4.2 4 0 0 4 4 3 2 Immunoglobulin domain GAIN PF16489.5 KFO98495.1 - 1.5e-08 34.3 3.5 3.4e-08 33.2 3.5 1.6 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain SEA PF01390.20 KFO98495.1 - 5e-08 33.0 2.8 6.3e-08 32.7 0.4 2.5 2 0 0 2 2 2 1 SEA domain V-set PF07686.17 KFO98495.1 - 5.7e-06 26.5 4.7 0.012 15.7 0.5 4.7 2 2 0 2 2 2 1 Immunoglobulin V-set domain Ig_5 PF16681.5 KFO98495.1 - 2.4e-05 24.6 0.8 0.002 18.5 0.1 3.2 2 0 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFO98495.1 - 0.0013 18.7 0.1 0.23 11.6 0.0 3.1 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 KFO98495.1 - 0.002 18.4 3.4 0.33 11.3 0.2 4.4 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFO98495.1 - 0.063 12.9 6.0 1.5 8.5 0.0 3.5 3 0 0 3 3 3 0 Immunoglobulin domain SH3_9 PF14604.6 KFO98498.1 - 3.2e-44 148.5 3.8 4.6e-16 58.4 0.1 3.5 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 KFO98498.1 - 5e-39 131.7 7.8 4.6e-13 48.6 0.2 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 KFO98498.1 - 2e-35 120.2 5.0 7e-12 44.9 0.0 3.5 3 0 0 3 3 3 3 Variant SH3 domain XFP PF03894.15 KFO98498.1 - 0.00047 19.9 0.0 0.72 9.6 0.0 3.1 3 0 0 3 3 3 2 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase betaPIX_CC PF16523.5 KFO98498.1 - 0.27 11.1 8.6 0.64 9.9 8.6 1.7 1 0 0 1 1 1 0 betaPIX coiled coil DUF724 PF05266.14 KFO98498.1 - 0.5 10.2 5.0 0.95 9.3 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Patched PF02460.18 KFO98499.1 - 3.7e-77 260.2 25.5 4.6e-71 240.0 16.6 3.1 1 1 2 3 3 3 3 Patched family Sterol-sensing PF12349.8 KFO98499.1 - 1.6e-12 47.5 5.7 1.6e-12 47.5 5.7 2.5 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Calici_coat_C PF08435.11 KFO98499.1 - 0.013 15.0 0.2 5.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Calicivirus coat protein C-terminal Ycf54 PF10674.9 KFO98499.1 - 0.11 12.8 0.0 35 4.8 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2488) DUF1133 PF06576.11 KFO98499.1 - 0.15 11.4 0.0 22 4.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1133) Phage_holin_3_6 PF07332.11 KFO98499.1 - 0.24 11.4 7.5 32 4.6 0.3 3.5 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III FAM176 PF14851.6 KFO98501.1 - 2.8e-62 208.7 0.1 3.2e-62 208.5 0.1 1.0 1 0 0 1 1 1 1 FAM176 family PTN13_u3 PF16599.5 KFO98501.1 - 0.0037 17.3 1.4 0.0055 16.8 1.4 1.3 1 0 0 1 1 1 1 Unstructured linker region on PTN13 protein between PDZ LYRIC PF15686.5 KFO98501.1 - 0.028 14.0 0.0 0.035 13.7 0.0 1.0 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family VirB3 PF05101.13 KFO98501.1 - 0.041 14.1 0.1 0.064 13.5 0.1 1.3 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein DUF555 PF04475.12 KFO98501.1 - 0.097 13.0 1.3 1.2 9.5 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF555) DUF4576 PF15144.6 KFO98501.1 - 0.15 11.9 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) DUF755 PF05501.11 KFO98501.1 - 1.4 9.2 6.3 2 8.7 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Ribosomal_L19 PF01245.20 KFO98502.1 - 5.4e-16 58.5 0.0 9.6e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 GCFC PF07842.12 KFO98503.1 - 2.6e-25 89.6 8.6 5.2e-25 88.6 5.3 2.7 2 1 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein RecQ_Zn_bind PF16124.5 KFO98503.1 - 0.39 11.5 5.3 45 4.9 0.2 4.0 3 0 0 3 3 3 0 RecQ zinc-binding SOCS PF12610.8 KFO98504.1 - 0.029 14.7 0.9 0.029 14.7 0.9 2.8 1 1 0 2 2 2 0 Suppressor of cytokine signalling XRCC4 PF06632.12 KFO98504.1 - 1.3 7.8 9.2 1.5 7.6 9.2 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 CDC45 PF02724.14 KFO98504.1 - 2 6.6 9.2 2.3 6.4 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein PH_13 PF16652.5 KFO98505.1 - 5.9e-72 240.6 0.8 5.9e-72 240.6 0.8 3.8 3 1 0 4 4 4 1 Pleckstrin homology domain SH3_9 PF14604.6 KFO98505.1 - 2.3e-66 219.5 4.2 1.7e-15 56.6 0.0 5.4 5 0 0 5 5 5 5 Variant SH3 domain SH3_1 PF00018.28 KFO98505.1 - 1.9e-65 216.3 9.8 4.8e-16 58.1 0.1 5.5 5 0 0 5 5 5 5 SH3 domain SH3_2 PF07653.17 KFO98505.1 - 2.3e-57 190.5 0.9 2.3e-13 49.6 0.1 5.5 5 0 0 5 5 5 5 Variant SH3 domain RhoGEF PF00621.20 KFO98505.1 - 5.5e-43 147.3 0.1 5.5e-43 147.3 0.1 3.3 2 1 1 3 3 2 1 RhoGEF domain EF-hand_4 PF12763.7 KFO98505.1 - 1.4e-29 102.1 0.0 1.9e-13 50.3 0.0 2.8 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand C2 PF00168.30 KFO98505.1 - 2.1e-22 79.3 0.0 5e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain EF-hand_1 PF00036.32 KFO98505.1 - 1.3e-09 36.9 0.2 0.0045 16.4 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFO98505.1 - 9.7e-08 31.4 0.5 0.62 10.1 0.0 4.2 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 KFO98505.1 - 1.5e-07 31.8 0.6 0.00055 20.3 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain pair PH PF00169.29 KFO98505.1 - 0.00078 19.9 0.1 0.0025 18.3 0.1 1.9 1 0 0 1 1 1 1 PH domain EF-hand_8 PF13833.6 KFO98505.1 - 0.014 15.2 0.2 1.6 8.7 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.6 KFO98505.1 - 0.031 13.8 0.9 8.7 6.0 0.1 3.3 3 0 0 3 3 3 0 EF hand DUF3800 PF12686.7 KFO98505.1 - 0.052 14.2 0.1 2.4 8.8 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3800) INTAP PF16617.5 KFO98505.1 - 4.8 7.6 13.5 0.11 12.9 3.9 2.9 2 1 0 2 2 2 0 Intersectin and clathrin adaptor AP2 binding region Profilin PF00235.19 KFO98507.1 - 2.8e-29 102.0 0.0 3.1e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Profilin ADH_zinc_N PF00107.26 KFO98508.1 - 3.7e-21 75.4 0.1 7.2e-21 74.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFO98508.1 - 3.5e-20 73.4 0.0 1.3e-19 71.6 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFO98508.1 - 3.5e-09 36.5 0.1 1.8e-06 27.8 0.0 3.0 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KFO98508.1 - 0.08 12.8 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase DUF4147 PF13660.6 KFO98508.1 - 0.12 11.9 1.0 1.4 8.4 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4147) RRM_1 PF00076.22 KFO98509.1 - 1.1e-16 60.3 0.3 9.7e-16 57.4 0.0 2.2 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFO98509.1 - 0.00027 20.5 0.0 0.00034 20.2 0.0 1.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FKBP_C PF00254.28 KFO98510.1 - 9.4e-28 96.4 0.0 1e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase WDCP PF15390.6 KFO98511.1 - 0 1090.9 0.1 0 1090.8 0.1 1.0 1 0 0 1 1 1 1 WD repeat and coiled-coil-containing protein family ANAPC4_WD40 PF12894.7 KFO98511.1 - 0.0079 16.5 0.2 0.066 13.5 0.1 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WDCP PF15390.6 KFO98512.1 - 0 1041.4 0.2 0 1041.3 0.2 1.0 1 0 0 1 1 1 1 WD repeat and coiled-coil-containing protein family SEP PF08059.13 KFO98513.1 - 3.9e-25 88.2 0.4 9e-25 87.1 0.1 1.8 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 KFO98513.1 - 3.2e-14 52.9 0.1 1.3e-13 50.9 0.0 2.1 2 0 0 2 2 2 1 UBX domain AAA PF00004.29 KFO98514.1 - 1e-47 161.9 0.0 1.2e-40 139.0 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 KFO98514.1 - 6.6e-18 64.6 0.1 1.6e-17 63.3 0.1 1.6 1 0 0 1 1 1 1 Bromodomain AAA_lid_3 PF17862.1 KFO98514.1 - 3.4e-12 46.0 0.0 1.1e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KFO98514.1 - 2.1e-08 34.8 0.1 0.00033 21.1 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain IstB_IS21 PF01695.17 KFO98514.1 - 5.7e-06 26.2 0.0 3.9e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 KFO98514.1 - 8.8e-05 22.7 0.0 0.00029 21.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFO98514.1 - 0.0015 18.8 1.0 0.05 13.9 0.1 3.5 3 1 0 3 3 2 1 AAA domain AAA_5 PF07728.14 KFO98514.1 - 0.0029 17.6 0.1 0.059 13.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KFO98514.1 - 0.0061 16.1 0.0 0.25 10.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF1088 PF06469.11 KFO98514.1 - 0.0082 15.8 1.1 0.02 14.6 1.1 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1088) RNA_helicase PF00910.22 KFO98514.1 - 0.012 16.0 0.0 0.058 13.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase DUF2075 PF09848.9 KFO98514.1 - 0.016 14.5 0.0 0.032 13.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 KFO98514.1 - 0.017 14.5 0.0 0.23 10.8 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 KFO98514.1 - 0.022 14.9 0.0 1.4 9.0 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain RuvB_N PF05496.12 KFO98514.1 - 0.022 14.5 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 KFO98514.1 - 0.028 14.4 0.0 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 KFO98514.1 - 0.034 14.7 2.9 0.076 13.6 0.0 2.7 2 1 0 2 2 1 0 AAA domain TIP49 PF06068.13 KFO98514.1 - 0.042 13.1 0.0 0.2 10.8 0.0 1.9 2 0 0 2 2 2 0 TIP49 P-loop domain Sigma54_activat PF00158.26 KFO98514.1 - 0.069 12.8 0.0 0.76 9.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.6 KFO98514.1 - 0.096 12.8 0.0 0.53 10.4 0.0 2.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFO98514.1 - 0.096 12.6 0.0 0.65 9.9 0.1 2.4 2 1 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 KFO98514.1 - 0.13 11.8 0.0 0.34 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 KFO98514.1 - 0.15 11.2 0.0 0.66 9.1 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_30 PF13604.6 KFO98514.1 - 0.19 11.4 0.0 0.91 9.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KFO98514.1 - 0.41 10.4 0.0 0.41 10.4 0.0 3.2 3 1 0 3 3 2 0 AAA domain DUF4746 PF15928.5 KFO98514.1 - 0.49 9.8 4.8 0.92 8.9 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4636 PF15468.6 KFO98514.1 - 2.6 7.7 6.2 0.7 9.5 2.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4636) Rnk_N PF14760.6 KFO98515.1 - 0.091 13.3 1.3 7.2 7.2 1.3 2.5 1 1 0 1 1 1 0 Rnk N-terminus Kelch_1 PF01344.25 KFO98516.1 - 4.8e-46 154.1 12.2 1.5e-13 50.1 0.0 6.4 7 0 0 7 7 7 5 Kelch motif Kelch_6 PF13964.6 KFO98516.1 - 6.3e-45 150.1 5.8 2e-10 40.6 0.0 6.4 1 1 5 6 6 6 6 Kelch motif BACK PF07707.15 KFO98516.1 - 1.7e-30 105.1 0.2 1.7e-30 105.1 0.2 1.6 2 0 0 2 2 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 KFO98516.1 - 2.5e-28 97.8 2.8 1.3e-09 37.9 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain BTB PF00651.31 KFO98516.1 - 7.4e-24 84.1 0.9 1.9e-23 82.8 0.9 1.7 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 KFO98516.1 - 3.8e-23 80.5 2.9 9.3e-06 25.4 0.0 6.9 6 1 1 7 7 7 4 Kelch motif Kelch_3 PF13415.6 KFO98516.1 - 4e-15 55.7 1.8 0.0021 18.3 0.0 6.2 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KFO98516.1 - 1.1e-14 54.0 18.0 0.0048 16.8 0.1 6.5 7 0 0 7 7 7 4 Kelch motif DUF1668 PF07893.13 KFO98516.1 - 0.0035 16.7 0.0 0.08 12.3 0.0 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1668) DUF3342 PF11822.8 KFO98516.1 - 0.015 15.5 0.2 0.12 12.6 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3342) PQQ_3 PF13570.6 KFO98516.1 - 0.054 14.0 3.9 16 6.1 0.1 4.1 4 0 0 4 4 4 0 PQQ-like domain IGPS PF00218.21 KFO98516.1 - 0.059 12.5 0.4 0.17 11.0 0.1 1.8 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Yae1_N PF09811.9 KFO98517.1 - 2e-15 56.2 48.8 1.8e+04 -13.1 48.8 5.1 1 1 0 1 1 1 0 Essential protein Yae1, N terminal LIDHydrolase PF10230.9 KFO98518.1 - 3.7e-85 285.7 0.0 4.4e-85 285.4 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 KFO98518.1 - 0.0011 18.9 0.0 0.0051 16.7 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_6 PF12697.7 KFO98518.1 - 0.0022 18.6 0.0 0.0027 18.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFO98518.1 - 0.03 13.6 0.0 0.041 13.1 0.0 1.4 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KFO98518.1 - 0.033 13.1 0.1 0.11 11.5 0.0 1.9 2 1 1 3 3 3 0 Chlorophyllase enzyme DUF900 PF05990.12 KFO98518.1 - 0.071 12.6 0.2 0.17 11.4 0.1 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 KFO98518.1 - 0.14 11.8 0.0 0.29 10.7 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold TGF_beta PF00019.20 KFO98519.1 - 6.3e-34 117.1 0.5 9.6e-34 116.5 0.5 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFO98519.1 - 1.2e-13 51.4 0.0 1.5e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 TGF-beta propeptide PX PF00787.24 KFO98520.1 - 1.5e-12 47.5 0.7 2.9e-12 46.5 0.1 1.8 2 0 0 2 2 2 1 PX domain RVT_1 PF00078.27 KFO98521.1 - 0.074 12.6 0.0 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFO98522.1 - 0.00016 21.2 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.11 KFO98522.1 - 0.26 11.0 0.6 0.43 10.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) Ras PF00071.22 KFO98523.1 - 1.1e-57 194.2 0.0 1.3e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO98523.1 - 4.8e-23 81.7 0.0 7.4e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO98523.1 - 6.5e-11 42.0 0.0 1.2e-10 41.1 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFO98523.1 - 0.00011 21.8 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFO98523.1 - 0.021 14.7 0.0 0.09 12.7 0.0 2.0 2 1 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 KFO98523.1 - 0.03 13.7 0.0 0.046 13.1 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFO98523.1 - 0.05 13.0 0.0 0.077 12.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AA_permease_2 PF13520.6 KFO98524.1 - 8.9e-62 209.3 47.3 1.1e-61 209.0 47.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFO98524.1 - 2.8e-22 79.0 44.2 7.1e-22 77.6 44.2 1.6 1 1 0 1 1 1 1 Amino acid permease Forkhead PF00250.18 KFO98525.1 - 5.8e-39 132.2 0.0 6.6e-39 132.1 0.0 1.0 1 0 0 1 1 1 1 Forkhead domain ADK PF00406.22 KFO98526.1 - 7.7e-34 117.0 0.0 9.9e-34 116.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KFO98526.1 - 2.7e-28 99.1 0.0 3.7e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KFO98526.1 - 0.0019 17.9 0.0 0.011 15.4 0.0 1.9 1 1 0 2 2 2 1 Thymidylate kinase AAA_18 PF13238.6 KFO98526.1 - 0.0021 18.6 0.1 0.003 18.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain STIL_N PF15253.6 KFO98527.1 - 4.9e-205 681.1 0.0 7.4e-205 680.5 0.0 1.3 1 0 0 1 1 1 1 SCL-interrupting locus protein N-terminus HLH PF00010.26 KFO98528.1 - 2.1e-18 66.0 0.2 2.2e-18 65.9 0.2 1.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain COE1_HLH PF16423.5 KFO98528.1 - 0.0014 18.3 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Transcription factor COE1 helix-loop-helix domain PMBR PF09373.10 KFO98528.1 - 0.066 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Pseudomurein-binding repeat MAP17 PF15807.5 KFO98529.1 - 2.9e-36 124.5 0.0 3.4e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Epiglycanin_C PF14654.6 KFO98529.1 - 0.016 15.3 1.3 0.02 14.9 1.3 1.3 1 1 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region EI24 PF07264.11 KFO98529.1 - 0.018 15.3 0.0 0.021 15.1 0.0 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) CopD PF05425.13 KFO98529.1 - 0.023 15.1 0.0 0.032 14.6 0.0 1.3 1 0 0 1 1 1 0 Copper resistance protein D Sigma_reg_N PF13800.6 KFO98529.1 - 0.084 13.2 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal TMEM52 PF14979.6 KFO98529.1 - 0.89 9.5 3.3 0.46 10.4 0.4 1.9 1 1 1 2 2 2 0 Transmembrane 52 p450 PF00067.22 KFO98530.1 - 1.3e-123 413.2 0.0 1.4e-123 413.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFO98531.1 - 3.5e-128 428.3 0.0 4.1e-128 428.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ATP11 PF06644.11 KFO98532.1 - 1.7e-49 169.1 0.7 1.8e-49 169.0 0.7 1.0 1 0 0 1 1 1 1 ATP11 protein Mob1_phocein PF03637.17 KFO98533.1 - 1.8e-78 262.4 0.4 2.1e-78 262.2 0.4 1.0 1 0 0 1 1 1 1 Mob1/phocein family Homeodomain PF00046.29 KFO98534.1 - 5.2e-22 77.4 3.9 5.2e-22 77.4 3.9 2.1 2 0 0 2 2 2 1 Homeodomain OAR PF03826.17 KFO98534.1 - 8.2e-06 25.5 1.2 2.1e-05 24.2 1.2 1.7 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 KFO98534.1 - 0.0094 15.8 0.1 0.027 14.3 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain Amidase PF01425.21 KFO98535.1 - 1.2e-110 370.6 0.0 1.3e-110 370.5 0.0 1.0 1 0 0 1 1 1 1 Amidase Methyltr_RsmB-F PF01189.17 KFO98536.1 - 1.8e-31 109.3 0.0 2.6e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KFO98536.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase UCR_hinge PF02320.16 KFO98537.1 - 1.1e-19 70.4 8.8 1.2e-19 70.2 8.8 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein LRR_6 PF13516.6 KFO98538.1 - 0.0009 19.1 4.0 0.6 10.3 0.0 4.6 5 0 0 5 5 5 2 Leucine Rich repeat SNF2_N PF00176.23 KFO98539.1 - 1.2e-36 126.1 0.0 2.1e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFO98539.1 - 2.5e-16 60.0 0.0 5.3e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KFO98539.1 - 1.7e-06 27.5 0.1 7.9e-06 25.2 0.1 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Rad54_N PF08658.10 KFO98539.1 - 5.9e-06 26.6 0.2 0.00019 21.7 0.1 2.5 2 0 0 2 2 2 1 Rad54 N terminal ResIII PF04851.15 KFO98539.1 - 0.0098 15.9 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CCB1 PF12046.8 KFO98539.1 - 0.049 13.0 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B DUF2075 PF09848.9 KFO98539.1 - 0.12 11.6 0.0 0.37 10.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) GNT-I PF03071.15 KFO98540.1 - 6.3e-50 170.2 0.2 1.4e-49 169.1 0.2 1.5 1 1 0 1 1 1 1 GNT-I family ILEI PF15711.5 KFO98540.1 - 1.2e-24 86.5 0.0 2.8e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 Interleukin-like EMT inducer MGAT2 PF05060.14 KFO98540.1 - 0.038 13.1 0.0 1 8.3 0.0 2.2 2 0 0 2 2 2 0 N-acetylglucosaminyltransferase II (MGAT2) Tetraspanin PF00335.20 KFO98541.1 - 1.6e-42 145.8 12.4 1.8e-42 145.6 12.4 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2981 PF11200.8 KFO98541.1 - 0.02 14.7 0.2 0.023 14.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) SUR7 PF06687.12 KFO98541.1 - 1.4 8.5 17.3 0.15 11.6 11.7 2.1 1 1 0 1 1 1 0 SUR7/PalI family PI3K_P85_iSH2 PF16454.5 KFO98542.1 - 8.9e-64 213.9 20.7 1.3e-63 213.4 20.7 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SH2 PF00017.24 KFO98542.1 - 1.9e-41 140.0 0.0 1.3e-19 70.0 0.0 2.6 2 0 0 2 2 2 2 SH2 domain RhoGAP PF00620.27 KFO98542.1 - 4.4e-18 65.5 0.1 4.3e-17 62.3 0.0 2.4 2 1 1 3 3 3 1 RhoGAP domain SH3_1 PF00018.28 KFO98542.1 - 9e-07 28.4 0.3 0.00026 20.5 0.0 2.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFO98542.1 - 2.5e-06 27.2 2.3 2.8e-06 27.1 0.4 2.2 2 1 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KFO98542.1 - 0.00054 19.6 0.0 0.0014 18.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Mod_r PF07200.13 KFO98542.1 - 0.094 12.8 14.0 0.12 12.5 5.2 2.6 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF5638 PF18688.1 KFO98542.1 - 0.3 11.4 6.9 0.047 14.0 1.1 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5638) Transcrip_act PF04949.13 KFO98542.1 - 1.3 8.8 13.0 4.2 7.2 4.6 2.9 1 1 2 3 3 3 0 Transcriptional activator Laminin_II PF06009.12 KFO98542.1 - 1.4 8.9 5.4 12 5.9 0.8 2.6 3 0 0 3 3 3 0 Laminin Domain II Exonuc_VII_L PF02601.15 KFO98542.1 - 4.5 6.8 7.9 7.1 6.1 7.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 KFO98542.1 - 5 6.4 6.4 7.3 5.9 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 KFO98542.1 - 9.8 6.2 6.4 2.8 8.0 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1908 PF08926.11 KFO98543.1 - 1.9e-141 470.2 0.8 1.9e-141 470.2 0.8 2.9 3 1 0 3 3 2 1 Domain of unknown function (DUF1908) Pkinase PF00069.25 KFO98543.1 - 8.9e-63 212.1 0.0 1.7e-62 211.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO98543.1 - 3.6e-26 92.0 0.0 8.2e-26 90.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase PDZ_6 PF17820.1 KFO98543.1 - 1e-11 44.5 0.1 6.3e-11 42.0 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 KFO98543.1 - 7.1e-09 35.9 0.0 1.6e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFO98543.1 - 3.8e-07 30.3 0.0 9.2e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain APH PF01636.23 KFO98543.1 - 4.8e-05 23.4 0.0 0.05 13.5 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KFO98543.1 - 0.00041 19.8 0.2 0.002 17.5 0.0 2.1 2 1 0 2 2 2 1 Kinase-like Tricorn_PDZ PF14685.6 KFO98543.1 - 0.0085 16.0 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 Tricorn protease PDZ domain Pkinase_fungal PF17667.1 KFO98543.1 - 0.0087 14.9 0.7 0.03 13.1 0.0 2.2 2 1 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 KFO98543.1 - 0.033 13.1 0.1 0.033 13.1 0.1 2.3 3 0 0 3 3 1 0 Haspin like kinase domain RIO1 PF01163.22 KFO98543.1 - 0.038 13.6 0.0 0.038 13.6 0.0 2.1 3 0 0 3 3 3 0 RIO1 family ACTL7A_N PF16840.5 KFO98543.1 - 0.088 12.9 0.2 0.24 11.5 0.2 1.7 1 0 0 1 1 1 0 Actin-like protein 7A N-terminus Folate_rec PF03024.14 KFO98545.1 - 8.5e-56 188.5 26.7 1.3e-55 187.9 26.7 1.3 1 0 0 1 1 1 1 Folate receptor family Kelch_1 PF01344.25 KFO98546.1 - 1.4e-76 251.8 22.8 4.4e-15 55.0 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFO98546.1 - 3.7e-52 173.0 4.6 2.9e-10 40.0 0.0 6.3 1 1 5 6 6 6 6 Kelch motif BACK PF07707.15 KFO98546.1 - 3.4e-31 107.4 1.1 8.4e-31 106.1 0.6 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 KFO98546.1 - 2.8e-29 101.6 0.0 5e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.6 KFO98546.1 - 1.1e-27 95.8 4.4 0.00012 22.2 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 KFO98546.1 - 8.9e-26 88.9 6.8 3.5e-06 26.8 0.1 6.6 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 KFO98546.1 - 1.5e-22 79.4 1.3 0.00049 20.0 0.0 6.3 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KFO98546.1 - 5e-10 39.2 10.3 0.05 13.6 0.0 6.3 7 0 0 7 7 7 3 Kelch motif DUF3342 PF11822.8 KFO98546.1 - 0.0044 17.2 0.0 0.031 14.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) SAM_3 PF18016.1 KFO98546.1 - 0.18 11.7 0.1 0.35 10.7 0.1 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF3429 PF11911.8 KFO98547.1 - 1.3e-34 119.5 9.2 1.7e-34 119.1 9.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Form-deh_trans PF09163.11 KFO98547.1 - 8.3 6.3 6.7 21 5.0 0.4 2.7 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane Vasculin PF15337.6 KFO98548.1 - 4.6e-43 146.0 4.6 1.5e-42 144.4 4.6 1.9 1 0 0 1 1 1 1 Vascular protein family Vasculin-like 1 SHNi-TPR PF10516.9 KFO98550.1 - 5e-15 54.7 6.4 7.8e-15 54.1 1.5 2.9 3 0 0 3 3 3 1 SHNi-TPR TPR_12 PF13424.6 KFO98550.1 - 1e-09 38.6 11.7 2.6e-08 34.0 5.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFO98550.1 - 3.5e-09 36.1 7.8 0.019 15.1 0.3 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFO98550.1 - 1.2e-07 31.3 6.0 0.016 15.0 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFO98550.1 - 4.3e-05 23.4 7.2 0.11 12.8 0.3 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFO98550.1 - 0.045 13.4 6.8 21 4.9 5.1 4.2 2 1 1 3 3 3 0 TPR repeat TPR_16 PF13432.6 KFO98550.1 - 0.065 13.9 13.7 0.96 10.1 1.2 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFO98550.1 - 0.076 13.9 0.1 0.076 13.9 0.1 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF5531 PF17671.1 KFO98550.1 - 0.11 12.4 0.2 0.11 12.4 0.2 4.3 3 2 1 4 4 4 0 Family of unknown function (DUF5531) TPR_6 PF13174.6 KFO98550.1 - 0.12 13.1 5.5 7 7.5 0.1 4.7 5 1 0 5 5 5 0 Tetratricopeptide repeat Aldo_ket_red PF00248.21 KFO98551.1 - 1.4e-54 185.3 0.1 2.5e-54 184.5 0.1 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family SLH PF00395.20 KFO98551.1 - 0.041 13.9 0.1 0.12 12.4 0.1 1.8 1 0 0 1 1 1 0 S-layer homology domain AhpC-TSA PF00578.21 KFO98552.1 - 1.7e-41 141.0 0.1 2.9e-41 140.3 0.0 1.4 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 KFO98552.1 - 9.4e-17 61.1 0.0 1.4e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KFO98552.1 - 1.1e-14 53.9 0.1 2.1e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Endothelin PF00322.17 KFO98552.1 - 0.14 11.8 0.6 0.29 10.8 0.6 1.5 1 0 0 1 1 1 0 Endothelin family MMACHC PF16690.5 KFO98553.1 - 4.5e-105 350.1 0.1 5.1e-105 349.9 0.1 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family Pkinase PF00069.25 KFO98556.1 - 5.2e-35 121.1 0.0 6.7e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO98556.1 - 2.6e-34 118.7 0.0 3.3e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFO98556.1 - 0.00048 19.0 0.0 0.00064 18.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFO98556.1 - 0.0058 16.0 0.1 0.012 15.0 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family HhH-GPD PF00730.25 KFO98557.1 - 2.8e-21 76.0 0.0 7.3e-21 74.7 0.0 1.6 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 KFO98557.1 - 6.9e-20 71.1 0.0 1.6e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.23 KFO98557.1 - 4.1e-09 35.8 0.3 1.7e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 KFO98557.1 - 0.041 14.2 4.8 0.041 14.2 4.8 2.1 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III SelP_N PF04592.14 KFO98558.1 - 6e-27 94.6 1.1 6.4e-27 94.5 1.1 1.0 1 0 0 1 1 1 1 Selenoprotein P, N terminal region SWIM PF04434.17 KFO98559.1 - 0.063 13.0 2.0 0.15 11.7 2.0 1.7 1 0 0 1 1 1 0 SWIM zinc finger URO-D PF01208.17 KFO98560.1 - 1.5e-133 445.2 0.0 1.7e-133 445.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) HECT PF00632.25 KFO98562.1 - 1.7e-50 172.2 0.1 2.3e-50 171.8 0.1 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MTH865 PF07747.11 KFO98562.1 - 0.17 11.6 0.0 2.3 8.0 0.0 2.4 2 0 0 2 2 2 0 MTH865-like family NTP_transferase PF00483.23 KFO98563.1 - 1.4e-17 64.1 0.0 2.5e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KFO98563.1 - 9.3e-15 55.3 0.0 1.3e-14 54.9 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 KFO98563.1 - 0.00013 20.3 5.5 0.00029 19.1 3.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 KFO98563.1 - 0.0002 20.4 0.6 0.0002 20.4 0.6 1.8 2 0 0 2 2 2 1 L-fucokinase Hexapep PF00132.24 KFO98563.1 - 0.0011 18.6 11.4 0.034 13.9 4.7 3.5 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) IspD PF01128.19 KFO98563.1 - 0.0045 16.8 0.0 0.0071 16.1 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Rop PF01815.16 KFO98563.1 - 0.065 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Rop protein BTB PF00651.31 KFO98564.1 - 3.5e-19 69.1 0.1 2.5e-17 63.1 0.0 2.2 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.15 KFO98564.1 - 1.9e-12 47.2 1.1 1.3e-11 44.5 0.2 2.3 3 0 0 3 3 3 1 BTB And C-terminal Kelch Tctex-1 PF03645.13 KFO98565.1 - 5.2e-20 71.6 0.0 6e-20 71.4 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family TetR_C_15 PF17918.1 KFO98565.1 - 0.077 13.8 0.0 0.12 13.1 0.0 1.4 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Pkinase PF00069.25 KFO98566.1 - 5.9e-70 235.6 0.0 9.3e-70 235.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain POLO_box PF00659.18 KFO98566.1 - 3e-37 126.6 3.2 1.4e-18 66.9 0.3 2.5 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_Tyr PF07714.17 KFO98566.1 - 6.5e-35 120.7 0.0 1e-34 120.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFO98566.1 - 1.7e-08 34.1 0.0 1.5e-06 27.8 0.0 2.4 1 1 1 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KFO98566.1 - 2.7e-05 23.2 0.0 5.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase PH_12 PF16457.5 KFO98566.1 - 0.078 13.5 0.2 2.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain Ribosomal_S8e PF01201.22 KFO98567.1 - 2.5e-53 179.9 0.8 2.9e-53 179.7 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e ICAT PF06384.11 KFO98567.1 - 0.074 13.3 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT Kinesin PF00225.23 KFO98568.1 - 3.4e-93 312.2 2.0 4.7e-93 311.7 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFO98568.1 - 1.5e-15 57.4 1.8 6.3e-15 55.4 0.0 2.7 2 1 0 3 3 3 1 Microtubule binding DUF2390 PF09523.10 KFO98568.1 - 0.0029 17.9 0.6 0.0075 16.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2390) DUF5339 PF17274.2 KFO98568.1 - 2.6 9.0 5.6 2.5 9.0 1.8 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5339) DUF5578 PF17741.1 KFO98569.1 - 9e-105 349.9 0.7 1e-104 349.7 0.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5578) Drf_GBD PF06371.13 KFO98569.1 - 0.0029 17.2 0.1 0.0052 16.4 0.1 1.4 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain DUF829 PF05705.14 KFO98570.1 - 3e-59 200.8 0.0 3.4e-59 200.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) RNF220 PF15926.5 KFO98571.1 - 3.7e-76 256.0 13.1 6.5e-50 170.1 0.9 3.0 2 1 1 3 3 3 2 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_2 PF13923.6 KFO98571.1 - 1.8e-13 50.0 11.4 1.8e-13 50.0 11.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFO98571.1 - 0.00012 21.8 7.5 0.00012 21.8 7.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFO98571.1 - 0.00065 19.6 8.0 0.00065 19.6 8.0 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFO98571.1 - 0.0012 18.6 10.0 0.0012 18.6 10.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFO98571.1 - 0.0029 17.9 10.6 0.0029 17.9 10.6 2.5 2 0 0 2 2 2 1 Ring finger domain zf-ribbon_3 PF13248.6 KFO98571.1 - 0.0064 15.9 0.9 3.2 7.3 0.2 3.0 2 0 0 2 2 2 2 zinc-ribbon domain Endonuclease_7 PF02945.15 KFO98571.1 - 0.0064 16.4 5.0 0.041 13.8 1.7 2.5 2 0 0 2 2 2 1 Recombination endonuclease VII Pox_A_type_inc PF04508.12 KFO98571.1 - 0.034 14.0 0.4 0.098 12.5 0.4 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat zf-RING_UBOX PF13445.6 KFO98571.1 - 0.19 11.8 14.3 0.077 13.0 8.7 2.6 2 0 0 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.6 KFO98571.1 - 0.26 11.2 12.9 0.22 11.4 6.6 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFO98571.1 - 0.52 10.4 5.4 0.2 11.7 2.6 1.7 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.7 KFO98571.1 - 3.1 7.9 6.5 36 4.5 4.5 3.0 2 1 0 2 2 2 0 Double zinc ribbon RNase_T PF00929.24 KFO98572.1 - 5.5e-42 144.1 0.0 6.6e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DMAP1 PF05499.12 KFO98573.1 - 9.1e-78 259.8 9.0 1.5e-77 259.1 9.0 1.4 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) SANT_DAMP1_like PF16282.5 KFO98573.1 - 7.9e-34 115.7 4.4 2.1e-33 114.3 4.4 1.8 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 ATP-synt_D PF01813.17 KFO98573.1 - 0.0048 16.7 3.3 0.0088 15.9 3.3 1.4 1 0 0 1 1 1 1 ATP synthase subunit D DUF2110 PF09883.9 KFO98573.1 - 0.1 12.2 0.1 0.2 11.2 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2110) FapA PF03961.13 KFO98573.1 - 7.7 5.0 8.9 6.1 5.3 6.0 1.9 1 1 0 2 2 2 0 Flagellar Assembly Protein A zf-C2H2 PF00096.26 KFO98574.1 - 1.2e-18 66.4 21.1 3.1e-06 27.3 4.1 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO98574.1 - 7.4e-13 48.3 13.9 2.2e-07 31.0 4.8 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFO98574.1 - 8.6e-11 41.7 19.3 0.00092 19.9 3.5 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO98574.1 - 0.032 14.5 8.7 1.1 9.6 0.3 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFO98574.1 - 0.046 14.1 10.4 0.88 10.1 0.9 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFO98574.1 - 0.11 12.3 12.5 3.9 7.3 1.4 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KFO98574.1 - 0.14 12.5 8.0 8.7 6.7 8.0 2.3 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 KFO98574.1 - 0.5 11.0 8.8 0.58 10.8 1.3 2.9 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2HE PF16278.5 KFO98574.1 - 7.2 7.1 11.1 31 5.1 6.0 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger SNF PF00209.18 KFO98575.1 - 4.9e-144 480.9 23.8 5.5e-144 480.7 23.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Caveolin PF01146.17 KFO98575.1 - 0.19 11.7 4.9 0.42 10.6 4.9 1.6 1 0 0 1 1 1 0 Caveolin Glyco_transf_7N PF13733.6 KFO98576.1 - 2.4e-57 192.3 0.0 3.9e-57 191.6 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 KFO98576.1 - 1.3e-31 108.0 1.7 1.9e-31 107.5 0.7 1.7 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KFO98576.1 - 0.027 13.9 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 ATP-synt_C PF00137.21 KFO98577.1 - 2.6e-27 94.9 33.9 6.9e-14 51.9 12.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CrgA PF06781.12 KFO98577.1 - 0.38 10.8 0.1 0.38 10.8 0.1 2.5 2 1 1 3 3 3 0 Cell division protein CrgA PIRT PF15099.6 KFO98577.1 - 0.64 9.6 6.0 4.5 6.9 0.9 2.3 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family Diphthamide_syn PF01866.17 KFO98578.1 - 3e-98 329.0 0.0 3.6e-98 328.8 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein MeaB PF03308.16 KFO98578.1 - 0.19 10.7 0.1 0.29 10.1 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Importin_rep_2 PF18786.1 KFO98579.1 - 1e-50 169.3 10.5 2.8e-26 91.1 1.1 3.0 3 0 0 3 3 3 2 Importin 13 repeat Importin_rep_3 PF18806.1 KFO98579.1 - 4.2e-36 122.8 0.0 1.5e-35 121.1 0.0 2.1 1 0 0 1 1 1 1 Importin 13 repeat Xpo1 PF08389.12 KFO98579.1 - 2.8e-28 98.8 8.5 1.3e-24 86.9 0.3 4.4 4 1 0 4 4 4 2 Exportin 1-like protein Importin_rep PF18773.1 KFO98579.1 - 2.1e-23 81.7 0.9 2.1e-23 81.7 0.9 2.2 3 0 0 3 3 3 1 Importin 13 repeat IBN_N PF03810.19 KFO98579.1 - 2.4e-09 37.0 1.1 1e-08 34.9 0.3 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain SLED PF12140.8 KFO98579.1 - 0.021 15.3 0.2 0.095 13.2 0.2 2.1 1 0 0 1 1 1 0 SLED domain Glyco_transf_29 PF00777.18 KFO98580.1 - 5.9e-69 232.5 0.0 7.3e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Y_phosphatase PF00102.27 KFO98581.1 - 4.7e-167 553.3 1.4 4.9e-85 284.8 0.1 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 KFO98581.1 - 3.1e-110 360.7 29.0 1.9e-16 60.2 0.4 9.0 8 1 0 8 8 8 8 Fibronectin type III domain I-set PF07679.16 KFO98581.1 - 6e-44 148.0 0.0 4.9e-16 58.6 0.0 4.1 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO98581.1 - 7.4e-39 132.2 1.1 1.8e-12 47.6 0.0 5.3 5 0 0 5 5 3 3 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFO98581.1 - 7.6e-23 80.9 21.1 0.086 13.4 0.1 10.2 9 1 0 9 9 9 7 Purple acid Phosphatase, N-terminal domain Ig_2 PF13895.6 KFO98581.1 - 1.7e-21 76.3 0.1 1.1e-07 32.0 0.0 4.6 4 0 0 4 4 4 3 Immunoglobulin domain Interfer-bind PF09294.10 KFO98581.1 - 1.4e-14 54.3 0.3 0.081 13.3 0.0 7.4 8 0 0 8 8 7 3 Interferon-alpha/beta receptor, fibronectin type III ig PF00047.25 KFO98581.1 - 1.7e-14 53.7 0.0 0.0057 16.8 0.0 4.2 3 0 0 3 3 3 3 Immunoglobulin domain fn3_2 PF16893.5 KFO98581.1 - 2.7e-14 53.1 1.1 0.035 14.3 0.0 8.2 8 0 0 8 8 8 3 Fibronectin type III domain V-set PF07686.17 KFO98581.1 - 4.7e-09 36.4 1.6 0.19 11.9 0.0 6.4 5 2 0 5 5 4 2 Immunoglobulin V-set domain DSPc PF00782.20 KFO98581.1 - 1.1e-08 35.0 0.0 0.0037 17.1 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFO98581.1 - 5e-08 33.2 0.1 0.014 15.3 0.0 3.2 3 0 0 3 3 3 2 Tyrosine phosphatase family Y_Y_Y PF07495.13 KFO98581.1 - 1.4e-06 28.1 0.7 0.023 14.7 0.0 3.5 3 0 0 3 3 3 2 Y_Y_Y domain C2-set_2 PF08205.12 KFO98581.1 - 2.6e-06 27.4 2.4 0.34 11.0 0.0 4.6 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain PTPlike_phytase PF14566.6 KFO98581.1 - 5.6e-05 23.3 0.1 0.08 13.1 0.0 3.2 3 0 0 3 3 3 1 Inositol hexakisphosphate Ig_5 PF16681.5 KFO98581.1 - 6.9e-05 23.2 0.0 0.1 13.0 0.0 3.8 3 0 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain DUF2369 PF10179.9 KFO98581.1 - 0.00033 21.0 0.1 19 5.7 0.0 6.0 5 1 0 6 6 6 0 Uncharacterised conserved protein (DUF2369) Ig_C17orf99 PF17736.1 KFO98581.1 - 0.00063 19.7 0.0 3.9 7.6 0.0 4.3 3 1 0 3 3 3 1 C17orf99 Ig domain fn3_4 PF16794.5 KFO98581.1 - 0.0043 16.9 4.2 3.5 7.6 0.0 5.8 7 0 0 7 7 6 1 Fibronectin-III type domain Insulin_TMD PF17870.1 KFO98581.1 - 0.028 14.5 0.3 0.063 13.4 0.3 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment ICAM_N PF03921.14 KFO98581.1 - 0.11 12.2 0.0 0.46 10.2 0.0 2.1 1 0 0 1 1 1 0 Intercellular adhesion molecule (ICAM), N-terminal domain DUF3377 PF11857.8 KFO98581.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) TMEM154 PF15102.6 KFO98581.1 - 0.25 11.3 1.7 0.39 10.6 0.1 2.1 2 0 0 2 2 2 0 TMEM154 protein family DUF1410 PF07198.11 KFO98581.1 - 0.67 10.5 2.8 7.9 7.1 1.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1410) AP_endonuc_2 PF01261.24 KFO98582.1 - 6.4e-23 81.3 0.0 9.1e-23 80.8 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Med8 PF10232.9 KFO98586.1 - 2.9e-88 295.4 0.4 3.8e-88 295.0 0.4 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 CSN4_RPN5_eIF3a PF18420.1 KFO98586.1 - 0.044 13.9 0.7 0.1 12.8 0.7 1.5 1 0 0 1 1 1 0 CSN4/RPN5/eIF3a helix turn helix domain Baculo_PEP_C PF04513.12 KFO98586.1 - 0.083 12.9 0.3 15 5.6 0.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ELO PF01151.18 KFO98587.1 - 3.2e-64 216.8 22.4 4e-64 216.5 22.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Spore_YhaL PF14147.6 KFO98587.1 - 0.32 10.7 0.1 0.32 10.7 0.1 2.5 3 0 0 3 3 3 0 Sporulation protein YhaL WD40 PF00400.32 KFO98588.1 - 9.5e-27 92.7 20.4 1.7e-07 31.8 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO98588.1 - 3.7e-20 72.0 8.4 2.1e-07 31.1 1.0 5.0 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFO98588.1 - 3.1e-07 30.4 0.7 0.024 14.5 0.1 2.5 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFO98588.1 - 7.4e-05 21.9 1.8 0.078 11.9 0.5 3.3 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein nos_propeller PF18764.1 KFO98588.1 - 0.037 14.0 0.6 3.1 7.8 0.0 2.9 3 0 0 3 3 3 0 Nitrous oxide reductase propeller repeat ELYS-bb PF16687.5 KFO98588.1 - 0.068 11.8 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin Nup160 PF11715.8 KFO98588.1 - 0.097 11.3 3.5 2.9 6.4 0.1 3.1 3 1 1 4 4 4 0 Nucleoporin Nup120/160 EpoR_lig-bind PF09067.10 KFO98589.1 - 1.8e-30 105.2 1.5 4.1e-28 97.6 0.3 2.7 3 0 0 3 3 3 2 Erythropoietin receptor, ligand binding fn3 PF00041.21 KFO98589.1 - 3.1e-15 56.3 4.0 3.7e-09 36.8 0.4 3.8 4 0 0 4 4 4 3 Fibronectin type III domain IL6Ra-bind PF09240.10 KFO98589.1 - 5.2e-07 30.0 3.7 0.0032 17.9 0.5 2.5 2 0 0 2 2 2 2 Interleukin-6 receptor alpha chain, binding Pur_ac_phosph_N PF16656.5 KFO98589.1 - 1e-05 26.0 0.1 0.007 16.9 0.0 3.0 2 1 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain ObR_Ig PF18589.1 KFO98589.1 - 0.018 15.4 0.0 0.26 11.7 0.0 2.5 2 0 0 2 2 2 0 Obesity receptor immunoglobulin like domain Tissue_fac PF01108.17 KFO98589.1 - 0.023 14.5 0.8 0.084 12.7 0.1 2.3 3 0 0 3 3 3 0 Tissue factor Interfer-bind PF09294.10 KFO98589.1 - 0.14 12.5 0.0 20 5.6 0.0 2.3 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III Pkinase_Tyr PF07714.17 KFO98590.1 - 3.8e-85 285.3 0.0 5.3e-85 284.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO98590.1 - 6e-40 137.3 0.0 1.5e-39 136.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 KFO98590.1 - 9.1e-30 102.9 0.8 2.9e-14 53.2 0.7 3.7 3 0 0 3 3 3 3 Fibronectin type III domain I-set PF07679.16 KFO98590.1 - 1.8e-08 34.3 0.0 0.0092 16.0 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO98590.1 - 8.3e-08 32.7 0.1 0.021 15.4 0.1 2.8 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFO98590.1 - 1.2e-06 28.6 0.1 0.0061 16.7 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFO98590.1 - 3.9e-05 23.9 0.0 0.033 14.5 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain hEGF PF12661.7 KFO98590.1 - 0.00015 22.3 7.5 0.00015 22.3 7.5 4.7 4 0 0 4 4 4 2 Human growth factor-like EGF Pur_ac_phosph_N PF16656.5 KFO98590.1 - 0.00022 21.8 0.0 0.068 13.7 0.1 3.5 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain EGF_2 PF07974.13 KFO98590.1 - 0.0071 16.7 11.0 0.0071 16.7 11.0 5.1 4 1 0 4 4 4 2 EGF-like domain Haspin_kinase PF12330.8 KFO98590.1 - 0.03 13.3 0.0 0.066 12.1 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KFO98590.1 - 0.035 12.9 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase V-set PF07686.17 KFO98590.1 - 0.072 13.3 0.0 9 6.5 0.0 2.6 2 0 0 2 2 2 0 Immunoglobulin V-set domain DUF4702 PF15774.5 KFO98590.1 - 0.11 11.4 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4702) APH PF01636.23 KFO98590.1 - 0.13 12.1 0.0 0.36 10.7 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family DSL PF01414.19 KFO98590.1 - 3.5 8.0 48.8 0.44 10.8 14.2 3.6 2 1 1 3 3 3 0 Delta serrate ligand Laminin_EGF PF00053.24 KFO98590.1 - 6.9 6.9 42.4 1.6 8.9 18.4 4.0 1 1 2 3 3 2 0 Laminin EGF domain EGF PF00008.27 KFO98590.1 - 8.5 6.8 47.9 0.08 13.3 10.7 4.7 4 0 0 4 4 4 0 EGF-like domain LRR19-TM PF15176.6 KFO98591.1 - 2.7e-31 107.6 0.0 4.4e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain LRR_8 PF13855.6 KFO98591.1 - 6.8e-19 67.4 36.7 4.5e-09 36.0 7.6 2.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFO98591.1 - 5.1e-05 23.5 23.8 0.017 15.5 2.2 3.4 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFO98591.1 - 7.4e-05 22.8 15.5 1.7 9.5 0.0 6.0 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_9 PF14580.6 KFO98591.1 - 0.0056 16.2 0.5 0.0081 15.7 0.5 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRRCT PF01463.24 KFO98591.1 - 0.0068 16.9 0.1 0.025 15.1 0.1 2.1 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain LRR_5 PF13306.6 KFO98591.1 - 0.032 14.2 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) TPKR_C2 PF16920.5 KFO98591.1 - 0.12 12.6 1.3 29 4.9 1.0 3.4 3 0 0 3 3 3 0 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_6 PF13516.6 KFO98591.1 - 8.9 6.7 20.2 6.9 7.0 0.1 5.4 5 0 0 5 5 5 0 Leucine Rich repeat TMEM125 PF15109.6 KFO98592.1 - 6.7e-55 184.2 8.3 6.7e-55 184.2 8.3 2.0 2 0 0 2 2 2 1 TMEM125 protein family UPF0182 PF03699.13 KFO98592.1 - 0.045 11.9 2.2 0.053 11.7 2.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF4231 PF14015.6 KFO98592.1 - 0.12 12.9 6.1 14 6.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF4234 PF14018.6 KFO98592.1 - 0.14 12.3 1.2 5.6 7.2 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) Serpentine_r_xa PF03383.15 KFO98592.1 - 1.2 9.0 4.8 1.3 8.9 1.8 2.3 1 1 2 3 3 3 0 Caenorhabditis serpentine receptor-like protein, class xa DUF4131 PF13567.6 KFO98592.1 - 1.7 8.3 12.0 3.3 7.3 3.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) WD40 PF00400.32 KFO98593.1 - 2.4e-07 31.3 9.8 0.16 12.9 0.1 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF1664 PF07889.12 KFO98593.1 - 0.0015 18.6 6.3 0.0015 18.6 6.3 5.9 3 2 3 6 6 6 2 Protein of unknown function (DUF1664) ADIP PF11559.8 KFO98593.1 - 0.012 15.7 14.8 0.012 15.7 14.8 6.0 1 1 5 6 6 6 0 Afadin- and alpha -actinin-Binding Bap31_Bap29_C PF18035.1 KFO98593.1 - 0.016 15.2 7.3 0.016 15.2 7.3 7.1 4 3 3 7 7 7 0 Bap31/Bap29 cytoplasmic coiled-coil domain Ebp2 PF05890.12 KFO98594.1 - 1e-76 258.0 28.7 1.2e-76 257.8 28.7 1.0 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 GvpL_GvpF PF06386.11 KFO98594.1 - 1.1 9.2 8.5 0.27 11.1 4.5 1.9 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF O-antigen_lig PF13425.6 KFO98594.1 - 1.3 7.8 5.2 1.6 7.4 5.2 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Cytochrom_B562 PF07361.11 KFO98594.1 - 1.7 9.3 17.7 1.6 9.4 14.9 2.1 1 1 1 2 2 2 0 Cytochrome b562 ALMT PF11744.8 KFO98594.1 - 4.6 6.0 9.3 5.3 5.8 9.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4407 PF14362.6 KFO98594.1 - 6 6.1 10.9 7.3 5.8 10.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) eIF3_N PF09440.10 KFO98594.1 - 6 7.3 11.1 5.4 7.5 8.4 2.1 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain FAM183 PF14886.6 KFO98595.1 - 8.1e-29 100.5 1.7 9.3e-29 100.3 1.7 1.1 1 0 0 1 1 1 1 FAM183A and FAM183B related DUF5311 PF17238.2 KFO98595.1 - 0.078 12.9 0.0 0.086 12.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5311) PIF1 PF05970.14 KFO98596.1 - 2e-50 172.0 1.4 5e-48 164.1 1.4 2.3 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KFO98596.1 - 4.2e-09 36.4 0.0 6.6e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KFO98596.1 - 8.4e-05 22.3 0.1 0.00025 20.8 0.1 1.8 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KFO98596.1 - 0.00013 22.3 0.0 0.00058 20.2 0.0 1.9 2 1 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.14 KFO98596.1 - 0.00072 17.6 0.0 0.001 17.1 0.0 1.1 1 0 0 1 1 1 1 Helicase SH3_13 PF18335.1 KFO98596.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain Glyco_transf_29 PF00777.18 KFO98597.1 - 2.8e-37 128.6 0.1 3.4e-37 128.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Peptidase_C13 PF01650.18 KFO98598.1 - 1.7e-40 139.1 0.0 2.4e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family ArgoMid PF16487.5 KFO98598.1 - 0.013 15.7 0.1 0.039 14.2 0.1 1.8 1 0 0 1 1 1 0 Mid domain of argonaute Peptidase_C14 PF00656.22 KFO98598.1 - 0.049 13.6 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Caspase domain ADK PF00406.22 KFO98599.1 - 4.8e-69 231.3 0.0 7.2e-34 117.1 0.0 2.2 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 KFO98599.1 - 4.1e-46 156.8 0.0 8.2e-25 87.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KFO98599.1 - 7.7e-13 49.1 0.0 6.6e-08 33.2 0.0 3.4 2 1 1 3 3 3 2 AAA domain AAA_33 PF13671.6 KFO98599.1 - 2.1e-05 24.7 0.2 0.00018 21.7 0.2 2.4 2 1 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 KFO98599.1 - 0.00013 21.8 0.6 0.3 10.8 0.1 3.1 2 1 1 3 3 3 1 Cytidylate kinase Thymidylate_kin PF02223.17 KFO98599.1 - 0.00051 19.8 3.1 0.042 13.5 0.1 3.5 4 0 0 4 4 4 1 Thymidylate kinase Hydin_ADK PF17213.3 KFO98599.1 - 0.00057 20.2 0.0 0.071 13.4 0.0 2.4 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain Zeta_toxin PF06414.12 KFO98599.1 - 0.0019 17.5 0.0 0.0099 15.2 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin dNK PF01712.19 KFO98599.1 - 0.02 14.8 0.2 0.1 12.4 0.0 2.3 3 0 0 3 3 3 0 Deoxynucleoside kinase AAA_19 PF13245.6 KFO98599.1 - 0.059 13.7 0.1 0.92 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KFO98599.1 - 0.13 12.7 0.0 0.87 9.9 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 KFO98599.1 - 0.16 12.2 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Myb_DNA-binding PF00249.31 KFO98600.1 - 3.9e-10 39.8 0.5 1.1e-09 38.3 0.5 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFO98600.1 - 8e-06 26.0 0.1 2.6e-05 24.4 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 KFO98600.1 - 1.2e-05 25.0 7.8 1.2e-05 25.0 7.8 2.3 2 0 0 2 2 2 1 Zinc finger, ZZ type UCH PF00443.29 KFO98601.1 - 5.4e-63 212.9 0.0 3.3e-62 210.3 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KFO98601.1 - 2.6e-24 85.6 1.3 1.6e-13 51.0 0.0 3.2 3 1 0 3 3 3 2 DUSP domain UCH_1 PF13423.6 KFO98601.1 - 4.5e-19 69.2 0.3 4.5e-19 69.2 0.3 4.0 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFO98601.1 - 8.5e-12 45.2 5.1 8.5e-12 45.2 5.1 3.4 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein U71 PF17474.2 KFO98601.1 - 0.14 12.1 5.1 2.1 8.3 0.1 3.5 3 0 0 3 3 3 0 Tegument protein UL11 homolog Miga PF10265.9 KFO98602.1 - 3.2e-253 841.6 5.9 3.7e-253 841.4 5.9 1.0 1 0 0 1 1 1 1 Mitoguardin I-set PF07679.16 KFO98603.1 - 6.3e-18 64.6 0.0 1.6e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO98603.1 - 1.5e-10 41.5 0.0 4.7e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFO98603.1 - 1.3e-06 28.5 0.1 6.6e-06 26.2 0.1 2.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFO98603.1 - 0.0067 16.7 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain COMM_domain PF07258.14 KFO98603.1 - 0.49 10.6 4.5 1.5 9.0 4.5 1.8 1 0 0 1 1 1 0 COMM domain KH_1 PF00013.29 KFO98604.1 - 4.5e-66 218.6 14.6 2.1e-18 65.9 0.1 4.3 4 0 0 4 4 4 4 KH domain KH_2 PF07650.17 KFO98604.1 - 4.3e-19 68.1 10.0 3.3e-05 23.6 0.3 4.3 4 0 0 4 4 4 4 KH domain DUF1897 PF09005.10 KFO98604.1 - 6.4e-13 48.0 20.7 1.1e-06 28.0 6.9 3.8 3 0 0 3 3 3 3 Domain of unknown function (DUF1897) KH_4 PF13083.6 KFO98604.1 - 3.8e-06 26.7 8.1 0.17 11.8 0.1 4.2 4 0 0 4 4 4 3 KH domain Secretin_N PF03958.17 KFO98604.1 - 0.00054 20.3 0.5 0.064 13.7 0.2 3.3 3 1 0 3 3 3 1 Bacterial type II/III secretion system short domain KH_5 PF13184.6 KFO98604.1 - 0.091 12.9 6.4 4.5 7.4 0.1 3.5 3 0 0 3 3 3 0 NusA-like KH domain DnaJ_C PF01556.18 KFO98605.1 - 1.9e-44 151.3 0.2 2.5e-44 150.9 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFO98605.1 - 5.8e-29 100.0 3.4 1.1e-28 99.2 3.4 1.5 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 KFO98605.1 - 0.18 11.7 0.0 0.5 10.3 0.0 1.7 1 0 0 1 1 1 0 A repeated domain in UCH-protein PDZ PF00595.24 KFO98606.1 - 1.3e-08 35.1 0.2 3e-08 33.9 0.1 1.7 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFO98606.1 - 0.015 15.1 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PDZ_2 PF13180.6 KFO98606.1 - 0.11 12.9 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 PDZ domain 7tm_1 PF00001.21 KFO98607.1 - 2.9e-09 36.7 9.0 3.5e-09 36.4 9.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Sri PF10327.9 KFO98607.1 - 0.0015 17.8 1.1 0.0015 17.8 1.1 1.7 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Sri DUF898 PF05987.13 KFO98607.1 - 0.43 9.6 4.4 0.55 9.2 4.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) YesK PF14150.6 KFO98607.1 - 2.5 8.4 7.3 2.4 8.4 0.3 2.9 2 1 1 3 3 3 0 YesK-like protein 7tm_2 PF00002.24 KFO98608.1 - 2.5e-58 197.2 27.9 4.9e-58 196.3 27.9 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GAIN PF16489.5 KFO98608.1 - 1.3e-44 152.2 4.3 1.7e-44 151.8 4.3 1.2 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain EGF_CA PF07645.15 KFO98608.1 - 2e-16 59.9 42.0 1.2e-08 35.0 11.7 3.8 3 0 0 3 3 3 3 Calcium-binding EGF domain GPS PF01825.21 KFO98608.1 - 1.1e-15 57.9 7.2 3.7e-15 56.2 7.2 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif EGF_3 PF12947.7 KFO98608.1 - 1.2e-11 44.6 52.5 2.9e-05 24.1 7.2 5.2 5 0 0 5 5 5 3 EGF domain cEGF PF12662.7 KFO98608.1 - 4.5e-09 36.1 27.3 5.3e-08 32.7 0.9 3.8 3 0 0 3 3 3 2 Complement Clr-like EGF-like Plasmod_Pvs28 PF06247.11 KFO98608.1 - 0.00048 20.4 44.3 0.0062 16.8 4.7 5.2 5 0 0 5 5 5 3 Pvs28 EGF domain hEGF PF12661.7 KFO98608.1 - 0.00096 19.7 5.6 0.00096 19.7 5.6 4.7 7 0 0 7 7 4 2 Human growth factor-like EGF EGF PF00008.27 KFO98608.1 - 0.0016 18.7 41.8 0.06 13.7 8.6 5.4 4 2 0 4 4 4 3 EGF-like domain DUF2371 PF10177.9 KFO98608.1 - 0.19 11.9 1.9 0.51 10.5 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) FXa_inhibition PF14670.6 KFO98608.1 - 1.2 9.5 44.1 0.031 14.5 10.1 4.5 3 2 2 5 5 5 0 Coagulation Factor Xa inhibitory site Pox_A14 PF05767.12 KFO98608.1 - 1.6 8.9 9.4 0.74 10.0 3.4 2.9 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Latrophilin PF02354.16 KFO98610.1 - 7.5e-174 578.2 13.4 1e-173 577.7 13.4 1.2 1 0 0 1 1 1 1 Latrophilin Cytoplasmic C-terminal region OLF PF02191.16 KFO98610.1 - 2.5e-85 286.0 5.6 4.5e-85 285.2 5.6 1.5 1 0 0 1 1 1 1 Olfactomedin-like domain 7tm_2 PF00002.24 KFO98610.1 - 3.4e-68 229.6 18.5 5.2e-68 229.0 18.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GAIN PF16489.5 KFO98610.1 - 2.3e-49 167.7 0.2 3.6e-49 167.0 0.2 1.3 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Gal_Lectin PF02140.18 KFO98610.1 - 1.1e-23 83.4 0.7 3e-23 82.1 0.7 1.8 1 0 0 1 1 1 1 Galactose binding lectin domain GPS PF01825.21 KFO98610.1 - 1.9e-15 57.1 5.6 5.2e-15 55.7 5.6 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif HRM PF02793.22 KFO98610.1 - 4.7e-09 36.4 1.4 1.2e-08 35.0 1.4 1.8 1 0 0 1 1 1 1 Hormone receptor domain zf-C2HCIx2C PF10782.9 KFO98610.1 - 0.92 9.5 4.8 2.1 8.3 4.8 1.5 1 0 0 1 1 1 0 Zinc-finger DUF5074 PF16819.5 KFO98610.1 - 0.99 9.5 5.7 1.8 8.6 1.0 3.4 1 1 1 3 3 3 0 Domain of unknown function (DUF5074) TTL PF03133.15 KFO98611.1 - 7.6e-79 264.9 0.4 7.6e-79 264.9 0.4 2.0 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 KFO98611.1 - 2.5e-07 30.3 0.0 0.021 14.1 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 KFO98611.1 - 6.1e-07 28.9 4.2 0.001 18.3 0.0 3.8 4 1 1 5 5 5 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 KFO98611.1 - 0.0009 19.3 0.0 0.0034 17.5 0.0 2.0 1 0 0 1 1 1 1 ATP-grasp domain GTP-bdg_M PF16360.5 KFO98611.1 - 0.0046 17.5 5.1 0.024 15.2 5.1 2.3 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region RimK PF08443.11 KFO98611.1 - 0.096 12.3 0.0 3 7.4 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Pkinase PF00069.25 KFO98612.1 - 2.2e-73 246.9 0.0 2.9e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO98612.1 - 5.5e-35 120.9 0.0 7.8e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFO98612.1 - 1.1e-08 34.7 0.0 2.8e-08 33.4 0.0 1.6 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFO98612.1 - 0.019 13.9 0.3 0.041 12.8 0.3 1.5 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KFO98612.1 - 0.072 13.0 0.1 2 8.3 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family SAM_1 PF00536.30 KFO98613.1 - 8.6e-10 38.9 0.0 1.1e-09 38.6 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFO98613.1 - 4.8e-05 23.4 0.0 7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFO98613.1 - 8e-05 22.5 0.0 9.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Uricase PF01014.18 KFO98614.1 - 9.8e-44 148.8 0.0 1.3e-23 83.6 0.0 2.0 2 0 0 2 2 2 2 Uricase Brix PF04427.18 KFO98615.1 - 3.7e-23 82.6 0.2 4.7e-23 82.3 0.2 1.1 1 0 0 1 1 1 1 Brix domain G-gamma PF00631.22 KFO98616.1 - 7.5e-16 57.9 0.0 8.1e-16 57.8 0.0 1.0 1 0 0 1 1 1 1 GGL domain FtsX_ECD PF18075.1 KFO98616.1 - 0.013 16.1 0.0 0.015 15.9 0.0 1.0 1 0 0 1 1 1 0 FtsX extracellular domain CP12 PF02672.15 KFO98616.1 - 0.051 14.3 0.1 0.062 14.1 0.1 1.1 1 0 0 1 1 1 0 CP12 domain SPATA1_C PF15743.5 KFO98617.1 - 1.3e-51 174.7 22.6 1.3e-51 174.7 22.6 2.0 2 0 0 2 2 2 1 Spermatogenesis-associated C-terminus Crl PF07417.12 KFO98617.1 - 0.037 14.1 2.8 0.12 12.4 2.6 2.0 1 1 0 1 1 1 0 Sigma factor-binding transcriptional regulator Crl RHH_1 PF01402.21 KFO98617.1 - 9.5 6.3 6.9 1.6 8.8 0.2 3.0 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family Glyco_hydro_18 PF00704.28 KFO98618.1 - 3.5e-33 115.7 0.6 4.5e-33 115.3 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Vitellogenin_N PF01347.22 KFO98619.1 - 2.8e-151 505.0 0.1 2.8e-151 505.0 0.1 2.9 2 1 0 2 2 2 1 Lipoprotein amino terminal region DUF1944 PF09175.10 KFO98619.1 - 1.1e-62 210.7 0.0 2.2e-62 209.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1944) DUF1943 PF09172.11 KFO98619.1 - 3.5e-48 164.4 13.3 4.2e-33 114.9 0.0 3.5 3 1 0 3 3 3 2 Domain of unknown function (DUF1943) VWD PF00094.25 KFO98619.1 - 4e-25 88.9 0.2 1.6e-24 87.0 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type D domain HEAT_2 PF13646.6 KFO98619.1 - 0.00095 19.5 0.8 3.3 8.2 0.0 3.7 3 1 0 3 3 3 2 HEAT repeats TonB_C PF03544.14 KFO98619.1 - 0.16 12.4 0.0 0.4 11.1 0.0 1.7 1 0 0 1 1 1 0 Gram-negative bacterial TonB protein C-terminal Utp14 PF04615.13 KFO98619.1 - 6 5.3 38.9 10 4.5 38.9 1.3 1 0 0 1 1 1 0 Utp14 protein ADIP PF11559.8 KFO98620.1 - 2.5e-38 131.5 20.8 2.5e-38 131.5 20.8 4.1 2 1 2 4 4 4 1 Afadin- and alpha -actinin-Binding Surfac_D-trimer PF09006.11 KFO98620.1 - 0.084 12.8 0.9 14 5.6 0.0 3.0 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation Sulfatase_C PF14707.6 KFO98620.1 - 0.24 12.1 0.2 0.24 12.1 0.2 3.3 2 2 1 3 3 3 0 C-terminal region of aryl-sulfatase DUF3775 PF12616.8 KFO98620.1 - 0.69 10.0 4.6 0.22 11.6 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3775) 7tm_1 PF00001.21 KFO98621.1 - 2.1e-34 119.0 23.5 3.3e-34 118.4 23.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFO98621.1 - 0.007 16.1 17.9 0.024 14.4 17.9 1.9 1 1 0 1 1 1 1 Olfactory receptor Orf78 PF06024.12 KFO98621.1 - 1.1 9.6 3.9 8.9 6.7 1.3 2.7 2 0 0 2 2 2 0 Orf78 (ac78) PKD_channel PF08016.12 KFO98622.1 - 2.7e-11 42.8 9.3 4.2e-11 42.2 9.3 1.3 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KFO98622.1 - 0.00012 21.4 17.9 0.00024 20.4 17.9 1.5 1 0 0 1 1 1 1 Ion transport protein DUF4522 PF15022.6 KFO98622.1 - 0.061 13.6 0.1 0.16 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4522) Claudin_3 PF06653.11 KFO98622.1 - 3.8 7.4 17.3 3.5 7.6 0.1 3.4 3 0 0 3 3 3 0 Tight junction protein, Claudin-like PKD_channel PF08016.12 KFO98623.1 - 1.9e-12 46.6 13.3 1.9e-12 46.6 13.3 1.5 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KFO98623.1 - 0.00013 21.3 26.2 0.00039 19.7 26.2 1.8 1 1 0 1 1 1 1 Ion transport protein RhoGAP PF00620.27 KFO98624.1 - 1.8e-44 151.2 0.1 3.7e-44 150.2 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain CARD PF00619.21 KFO98625.1 - 1.8e-15 56.7 0.3 2.8e-15 56.1 0.3 1.2 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 KFO98625.1 - 0.0037 17.2 0.1 0.0061 16.5 0.1 1.4 1 0 0 1 1 1 1 Caspase recruitment domain TetR_C_8 PF14278.6 KFO98625.1 - 0.081 13.0 0.1 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region Amidinotransf PF02274.17 KFO98626.1 - 0.0009 18.4 0.0 0.0009 18.4 0.0 1.3 1 1 0 1 1 1 1 Amidinotransferase TTRAP PF14203.6 KFO98626.1 - 0.85 9.6 3.7 2.1 8.4 0.0 2.7 3 0 0 3 3 3 0 Putative tranposon-transfer assisting protein Cys_knot PF00007.22 KFO98627.1 - 1.4e-16 60.6 13.5 1.4e-16 60.6 13.5 3.2 4 0 0 4 4 4 1 Cystine-knot domain VWC PF00093.18 KFO98627.1 - 2.1e-10 40.7 12.5 2.1e-10 40.7 12.5 4.9 3 1 1 4 4 4 1 von Willebrand factor type C domain TSP_1 PF00090.19 KFO98627.1 - 4.3e-05 23.6 8.1 4.3e-05 23.6 8.1 3.8 4 1 0 4 4 4 1 Thrombospondin type 1 domain Sclerostin PF05463.11 KFO98627.1 - 0.00034 20.4 5.8 0.00061 19.6 5.8 1.6 1 0 0 1 1 1 1 Sclerostin (SOST) zf-HIT PF04438.16 KFO98628.1 - 4.2e-05 23.3 13.5 4.2e-05 23.3 13.5 1.9 2 0 0 2 2 2 1 HIT zinc finger zf-B_box PF00643.24 KFO98628.1 - 1.9 8.7 9.3 4.8 7.4 9.3 1.7 1 0 0 1 1 1 0 B-box zinc finger Collagen PF01391.18 KFO98629.1 - 5e-146 474.6 567.5 2.9e-10 39.7 25.5 19.9 2 2 16 18 18 18 16 Collagen triple helix repeat (20 copies) COLFI PF01410.18 KFO98629.1 - 1.6e-51 174.9 0.1 1.5e-26 93.1 0.0 2.2 1 1 1 2 2 2 2 Fibrillar collagen C-terminal domain ADIP PF11559.8 KFO98630.1 - 0.0072 16.4 16.1 0.0072 16.4 16.1 6.1 1 1 5 6 6 6 2 Afadin- and alpha -actinin-Binding DUF1424 PF07232.11 KFO98630.1 - 0.058 12.4 2.1 1.4 7.8 0.1 2.5 2 1 0 2 2 2 0 Putative rep protein (DUF1424) Imm7 PF15585.6 KFO98630.1 - 5.4 7.3 17.7 5 7.4 0.3 4.5 2 2 1 4 4 4 0 Immunity protein 7 IMPa_helical PF18642.1 KFO98630.1 - 5.9 7.4 10.9 0.44 11.0 0.4 3.3 3 0 0 3 3 3 0 Immunomodulating metalloprotease helical domain BAR PF03114.18 KFO98631.1 - 8.9e-69 231.8 6.4 1.2e-68 231.4 6.4 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 KFO98631.1 - 8.5e-11 41.6 0.0 2.3e-10 40.1 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain BAR_2 PF10455.9 KFO98631.1 - 4.5e-09 35.8 1.0 5.4e-09 35.6 1.0 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 KFO98631.1 - 6e-09 36.0 0.3 1e-08 35.2 0.3 1.3 1 0 0 1 1 1 1 BAR domain of APPL family SH3_2 PF07653.17 KFO98631.1 - 7.8e-08 31.9 0.0 1.6e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFO98631.1 - 8e-08 31.8 0.0 1.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Sep15_SelM PF08806.11 KFO98632.1 - 2.3e-12 46.9 0.0 2.4e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 Sep15/SelM redox domain Sulfotransfer_2 PF03567.14 KFO98634.1 - 5.8e-40 137.8 0.6 7.5e-40 137.4 0.6 1.1 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 KFO98634.1 - 0.00022 20.2 0.0 0.00031 19.7 0.0 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_1 PF00685.27 KFO98634.1 - 0.0051 16.3 0.0 0.0074 15.8 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain DICT PF10069.9 KFO98634.1 - 0.085 12.6 0.6 1.1 9.0 0.1 2.3 2 0 0 2 2 2 0 Sensory domain in DIguanylate Cyclases and Two-component system DUF2129 PF09902.9 KFO98634.1 - 0.12 12.4 1.1 0.28 11.3 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2129) RVT_1 PF00078.27 KFO98635.1 - 0.00021 20.9 0.0 0.00042 19.9 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.11 KFO98635.1 - 0.23 11.2 0.6 0.43 10.3 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) Pkinase PF00069.25 KFO98636.1 - 1.1e-60 205.2 0.0 2.3e-60 204.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO98636.1 - 9.1e-39 133.3 0.0 1.3e-38 132.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 KFO98636.1 - 7.2e-33 112.5 16.5 3.7e-17 62.2 8.0 2.4 2 0 0 2 2 2 2 Hr1 repeat Kinase-like PF14531.6 KFO98636.1 - 4.6e-07 29.4 0.0 3.4e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Uds1 PF15456.6 KFO98636.1 - 0.00016 21.8 5.8 0.011 15.9 1.8 2.4 2 0 0 2 2 2 2 Up-regulated During Septation Haspin_kinase PF12330.8 KFO98636.1 - 0.00049 19.2 0.0 0.00049 19.2 0.0 2.1 3 0 0 3 3 3 1 Haspin like kinase domain C2 PF00168.30 KFO98636.1 - 0.0089 16.3 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 C2 domain PL48 PF15903.5 KFO98636.1 - 0.23 10.4 2.0 2.2 7.2 0.2 2.2 2 0 0 2 2 2 0 Filopodia upregulated, FAM65 Fib_alpha PF08702.10 KFO98636.1 - 8.1 6.6 7.8 1.7 8.8 3.2 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TFIIB PF00382.19 KFO98637.1 - 7e-53 176.6 2.1 1.1e-25 89.4 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KFO98637.1 - 1.7e-14 53.0 0.4 2.8e-14 52.4 0.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 KFO98637.1 - 2.8e-09 36.8 0.0 7.3e-07 29.0 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFO98637.1 - 0.0016 18.5 0.4 0.07 13.2 0.0 2.4 1 1 1 2 2 2 1 Cyclin, C-terminal domain RB_B PF01857.20 KFO98637.1 - 0.0028 17.7 0.1 0.0079 16.2 0.1 1.7 1 1 0 2 2 2 1 Retinoblastoma-associated protein B domain Sigma70_r4 PF04545.16 KFO98637.1 - 0.014 14.9 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 Pannexin_like PF12534.8 KFO98638.1 - 6.4e-127 423.5 14.9 8.5e-127 423.0 14.9 1.2 1 0 0 1 1 1 1 Pannexin-like TM region of LRRC8 LRR_8 PF13855.6 KFO98638.1 - 3.9e-28 97.0 47.5 1.9e-11 43.5 4.3 7.7 5 2 3 8 8 8 6 Leucine rich repeat LRR_4 PF12799.7 KFO98638.1 - 6.8e-17 61.3 60.1 7.4e-06 26.2 0.3 9.1 5 2 6 11 11 11 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFO98638.1 - 2e-07 31.0 7.8 0.00043 20.2 1.8 3.8 1 1 3 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFO98638.1 - 7.4e-07 28.8 18.5 0.0034 16.9 1.6 3.7 1 1 3 4 4 4 4 Leucine-rich repeat Pannexin_like PF12534.8 KFO98639.1 - 1.2e-149 498.1 4.1 1.7e-149 497.7 4.1 1.2 1 0 0 1 1 1 1 Pannexin-like TM region of LRRC8 LRR_8 PF13855.6 KFO98639.1 - 1.4e-29 101.6 33.0 4.8e-10 39.1 1.1 7.6 3 2 4 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 KFO98639.1 - 2.2e-20 72.4 41.0 0.00026 21.3 0.2 9.7 6 3 3 10 10 10 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFO98639.1 - 3.6e-09 36.6 8.3 3.9e-05 23.6 0.4 4.2 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFO98639.1 - 9.1e-05 22.0 12.6 0.17 11.4 0.3 4.2 2 1 2 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.6 KFO98639.1 - 0.024 14.7 22.8 0.78 9.9 0.1 8.5 9 0 0 9 9 9 0 Leucine Rich repeat LRR_1 PF00560.33 KFO98639.1 - 0.14 12.8 33.6 6 7.8 0.0 11.1 11 0 0 11 11 11 0 Leucine Rich Repeat Pannexin_like PF12534.8 KFO98640.1 - 2.2e-157 523.6 6.3 3.3e-157 523.0 6.3 1.3 1 0 0 1 1 1 1 Pannexin-like TM region of LRRC8 LRR_8 PF13855.6 KFO98640.1 - 8.8e-35 118.3 23.9 5.9e-12 45.2 0.4 6.9 4 1 3 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 KFO98640.1 - 1.7e-24 85.5 39.2 2.8e-06 27.5 1.2 9.1 3 2 6 11 11 11 10 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFO98640.1 - 1.5e-11 44.1 14.8 4.4e-06 26.3 1.4 4.2 2 1 2 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 KFO98640.1 - 8.9e-08 31.7 35.4 0.12 13.0 0.2 10.8 10 2 0 10 10 10 6 Leucine Rich Repeat AKAP95 PF04988.12 KFO98641.1 - 5.9e-67 225.0 14.1 1.1e-66 224.2 14.1 1.4 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.7 KFO98641.1 - 0.046 14.0 10.3 0.85 10.0 1.6 2.4 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF678 PF05077.12 KFO98641.1 - 0.069 13.3 0.4 4.3 7.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF678) zf-Di19 PF05605.12 KFO98641.1 - 0.16 12.3 8.0 0.78 10.1 0.6 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Eapp_C PF10238.9 KFO98641.1 - 0.31 11.1 8.3 0.79 9.8 3.0 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein Homeodomain PF00046.29 KFO98642.1 - 3.1e-19 68.5 2.1 4.4e-19 68.1 2.1 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO98642.1 - 0.12 12.3 0.2 0.41 10.6 0.1 1.9 2 0 0 2 2 2 0 Homeobox KN domain zf-C2H2_4 PF13894.6 KFO98644.1 - 1.3e-18 66.1 47.8 0.00093 19.8 0.3 9.1 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2 PF00096.26 KFO98644.1 - 3.7e-06 27.1 57.1 0.00034 20.9 0.5 9.0 8 1 0 8 8 8 4 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 KFO98644.1 - 0.00059 19.4 13.1 0.15 11.7 0.5 5.0 5 0 0 5 5 5 3 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 KFO98644.1 - 0.011 16.0 19.2 0.92 9.9 0.0 6.7 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFO98644.1 - 0.013 15.2 1.1 0.013 15.2 1.1 7.2 7 0 0 7 7 7 0 C2H2-type zinc-finger domain zf-C2H2_7 PF15269.6 KFO98644.1 - 0.026 14.6 23.5 0.12 12.5 0.5 5.3 4 1 1 5 5 5 0 Zinc-finger Metallothio_Pro PF02069.16 KFO98644.1 - 0.39 11.0 5.0 1.7 9.0 5.0 2.1 1 0 0 1 1 1 0 Prokaryotic metallothionein zf-C2H2_8 PF15909.5 KFO98644.1 - 0.48 10.7 18.7 0.4 11.0 3.3 4.1 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 KFO98644.1 - 1.6 9.1 27.5 4.6 7.6 0.0 6.3 4 1 2 6 6 6 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 KFO98644.1 - 9.8 6.4 20.3 0.92 9.7 5.7 5.4 5 1 0 5 5 5 0 FYVE zinc finger RVT_1 PF00078.27 KFO98645.1 - 0.00015 21.3 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.11 KFO98645.1 - 0.25 11.1 0.6 0.41 10.4 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) Sec63 PF02889.16 KFO98646.1 - 5.4e-48 163.4 2.4 5.4e-48 163.4 2.4 1.8 2 0 0 2 2 2 1 Sec63 Brl domain DEAD PF00270.29 KFO98646.1 - 3.6e-25 88.8 0.0 1.2e-24 87.0 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFO98646.1 - 1.1e-12 48.3 0.0 3e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFO98646.1 - 2.9e-11 43.7 0.2 8e-10 39.0 0.0 3.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFO98646.1 - 0.0017 18.6 0.0 0.0051 17.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFO98646.1 - 0.16 11.6 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 KFO98647.1 - 1.1e-48 165.9 0.0 3.3e-26 92.2 0.1 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KFO98647.1 - 2e-16 60.1 0.0 4.3e-13 49.1 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KFO98647.1 - 0.019 14.9 0.0 0.15 12.0 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family TMEM100 PF16311.5 KFO98647.1 - 0.041 13.5 1.3 0.11 12.1 0.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 100 Zona_pellucida PF00100.23 KFO98648.1 - 3.3e-41 141.8 0.9 7.2e-41 140.7 0.9 1.6 1 0 0 1 1 1 1 Zona pellucida-like domain Abhydrolase_1 PF00561.20 KFO98649.1 - 6.9e-25 88.2 0.0 7.4e-23 81.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFO98649.1 - 1.1e-19 72.0 0.0 1.3e-19 71.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFO98649.1 - 5.8e-10 38.8 0.0 5.7e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ndr PF03096.14 KFO98649.1 - 6.8e-05 21.7 0.0 0.0074 15.0 0.0 2.0 2 0 0 2 2 2 2 Ndr family PGAP1 PF07819.13 KFO98649.1 - 0.013 15.2 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 KFO98649.1 - 0.095 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.18 KFO98649.1 - 0.18 11.3 0.0 16 5.0 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family BTB PF00651.31 KFO98650.1 - 8.1e-23 80.8 0.0 2.6e-21 75.9 0.0 2.2 1 1 1 2 2 2 2 BTB/POZ domain DUF4596 PF15363.6 KFO98651.1 - 4e-27 94.2 6.0 4e-27 94.2 6.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4596) BACK PF07707.15 KFO98651.1 - 0.14 12.3 0.7 2.4 8.3 0.1 2.5 2 0 0 2 2 2 0 BTB And C-terminal Kelch DUF4580 PF15162.6 KFO98652.1 - 2.5e-78 261.3 1.5 2.7e-78 261.1 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4580) Kinetochor_Ybp2 PF08568.10 KFO98653.1 - 1.8e-86 291.1 20.1 2.2e-86 290.8 20.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin zf-AD PF07776.15 KFO98653.1 - 0.0012 19.0 0.1 0.0012 19.0 0.1 2.2 2 0 0 2 2 2 1 Zinc-finger associated domain (zf-AD) RPAP2_Rtr1 PF04181.13 KFO98654.1 - 2.3e-23 82.3 3.0 2.3e-23 82.3 3.0 2.3 2 0 0 2 2 2 1 Rtr1/RPAP2 family Peptidase_M27 PF01742.17 KFO98654.1 - 0.0065 15.6 0.1 0.013 14.7 0.1 1.4 1 0 0 1 1 1 1 Clostridial neurotoxin zinc protease DUF4692 PF15763.5 KFO98654.1 - 1.8 9.0 16.9 0.54 10.7 3.3 3.1 2 1 1 3 3 3 0 Regulator of human erythroid cell expansion (RHEX) zf-C2H2 PF00096.26 KFO98655.1 - 4.3e-29 99.3 48.2 8.2e-06 26.0 1.0 6.8 7 0 0 7 7 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO98655.1 - 3.3e-27 93.6 41.9 1.4e-06 28.5 2.0 7.2 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFO98655.1 - 1.1e-22 78.8 41.6 0.00074 20.1 0.8 6.6 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFO98655.1 - 3.9e-15 55.4 39.1 0.0026 17.7 2.8 6.5 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO98655.1 - 4.3e-15 55.6 15.4 0.0081 16.4 0.0 6.4 6 0 0 6 6 6 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFO98655.1 - 2.7e-07 30.7 26.1 0.011 16.1 0.3 5.8 6 0 0 6 6 6 3 Zinc-finger of C2H2 type Ta0938 PF11494.8 KFO98655.1 - 7.2e-05 23.0 1.6 0.031 14.6 0.0 2.7 2 1 1 3 3 3 1 Ta0938 zf-BED PF02892.15 KFO98655.1 - 0.00088 19.3 29.3 0.02 14.9 0.9 5.7 4 1 1 6 6 6 2 BED zinc finger zf_UBZ PF18439.1 KFO98655.1 - 0.0017 17.9 17.3 6.7 6.4 0.1 6.1 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 KFO98655.1 - 0.0022 18.3 21.6 0.15 12.4 3.6 4.4 3 1 1 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-CHCC PF10276.9 KFO98655.1 - 0.0085 16.1 10.2 0.47 10.6 0.3 4.5 4 0 0 4 4 4 2 Zinc-finger domain zf-C2H2_3rep PF18868.1 KFO98655.1 - 0.011 16.4 20.2 0.68 10.6 2.1 4.9 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf_C2H2_ZHX PF18387.1 KFO98655.1 - 0.026 14.2 1.5 0.026 14.2 1.5 3.4 3 2 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain Prok-RING_1 PF14446.6 KFO98655.1 - 0.055 13.4 15.9 9.2 6.3 0.1 5.9 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 FYVE PF01363.21 KFO98655.1 - 0.061 13.5 25.8 1.6 8.9 9.3 3.9 1 1 3 4 4 4 0 FYVE zinc finger GAGA PF09237.11 KFO98655.1 - 0.086 12.7 6.8 6.6 6.6 0.0 4.2 2 2 2 4 4 4 0 GAGA factor zinc_ribbon_15 PF17032.5 KFO98655.1 - 0.17 12.7 13.2 3.8 8.3 1.5 3.5 1 1 2 3 3 3 0 zinc-ribbon family BolA PF01722.18 KFO98655.1 - 0.18 12.1 7.5 0.98 9.7 0.5 3.4 2 2 0 2 2 2 0 BolA-like protein HypA PF01155.19 KFO98655.1 - 0.19 11.7 11.5 1.2 9.2 0.5 3.4 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_11 PF16622.5 KFO98655.1 - 0.2 11.4 29.8 4.9 7.0 0.2 6.3 6 0 0 6 6 6 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KFO98655.1 - 0.21 11.8 26.4 1.2 9.3 2.9 5.7 4 2 2 6 6 6 0 Zinc ribbon domain HNH_5 PF14279.6 KFO98655.1 - 0.21 11.5 17.7 3.7 7.5 0.8 5.7 6 1 0 6 6 5 0 HNH endonuclease zf-C2HC_2 PF13913.6 KFO98655.1 - 0.27 11.2 25.5 1.8 8.6 1.0 6.0 6 0 0 6 6 6 0 zinc-finger of a C2HC-type PyrI_C PF02748.15 KFO98655.1 - 0.63 10.0 13.9 1.6 8.7 0.1 5.1 5 1 1 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf_ZIC PF18366.1 KFO98655.1 - 0.64 10.2 18.1 2.5 8.3 0.1 5.2 3 1 3 6 6 6 0 Zic proteins zinc finger domain XPA_N PF01286.18 KFO98655.1 - 1.6 8.8 23.6 8 6.6 0.1 6.7 7 0 0 7 7 7 0 XPA protein N-terminal Ribosomal_S27e PF01667.17 KFO98655.1 - 2.1 8.1 10.4 1.4 8.7 0.1 4.5 4 1 1 5 5 5 0 Ribosomal protein S27 zf-C2H2_2 PF12756.7 KFO98655.1 - 2.7 8.4 23.8 35 4.8 0.5 5.6 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) Zf_RING PF16744.5 KFO98655.1 - 3.3 7.9 17.9 14 5.9 0.6 5.4 1 1 5 6 6 6 0 KIAA1045 RING finger zf-AN1 PF01428.16 KFO98655.1 - 4.6 7.5 34.0 5.3 7.3 0.7 6.8 5 2 2 7 7 7 0 AN1-like Zinc finger Arc_trans_TRASH PF08394.10 KFO98655.1 - 5.7 7.4 9.2 57 4.2 0.1 4.7 3 2 0 3 3 3 0 Archaeal TRASH domain ADK_lid PF05191.14 KFO98655.1 - 6.5 6.8 15.3 22 5.2 4.6 4.7 3 2 1 4 4 4 0 Adenylate kinase, active site lid RabGAP-TBC PF00566.18 KFO98656.1 - 1.6e-54 184.8 2.8 1.6e-54 184.8 2.8 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF1129 PF06570.11 KFO98656.1 - 0.02 14.4 0.3 0.072 12.6 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) PARP_reg PF02877.14 KFO98656.1 - 0.23 11.5 7.9 0.14 12.3 0.7 3.0 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain Ribosomal_L5e PF17144.4 KFO98657.1 - 9.5e-95 315.1 1.0 2e-94 314.1 1.0 1.5 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KFO98657.1 - 5.6e-40 136.2 10.1 5.6e-40 136.2 10.1 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF1476 PF07345.11 KFO98657.1 - 0.009 16.4 0.2 0.021 15.2 0.2 1.6 1 0 0 1 1 1 1 ATPase inhibitor subunit zeta PIP49_C PF12260.8 KFO98658.1 - 1.6e-66 223.6 0.1 2.6e-66 222.9 0.1 1.4 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 PIP49_N PF14875.6 KFO98658.1 - 9e-58 194.6 2.8 2.3e-57 193.3 0.1 2.2 2 0 0 2 2 2 1 N-term cysteine-rich ER, FAM69 EF-hand_5 PF13202.6 KFO98658.1 - 0.12 11.9 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 EF hand Mtf2_C PF14061.6 KFO98659.1 - 3.2e-27 94.4 0.1 6.3e-27 93.5 0.1 1.5 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 PHD PF00628.29 KFO98659.1 - 8.4e-17 60.8 27.7 1.9e-12 46.9 8.0 2.4 2 0 0 2 2 2 2 PHD-finger Tudor_2 PF18104.1 KFO98659.1 - 3.3e-13 49.0 0.0 7.6e-13 47.9 0.0 1.7 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain DUF3682 PF12446.8 KFO98659.1 - 0.00021 21.8 3.2 0.00042 20.8 3.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3682) DUF4537 PF15057.6 KFO98659.1 - 0.00043 20.3 0.0 0.00099 19.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Prok-RING_1 PF14446.6 KFO98659.1 - 0.0015 18.5 6.4 0.0015 18.5 6.4 3.0 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 DUF1325 PF07039.11 KFO98659.1 - 0.003 17.6 0.0 0.0065 16.6 0.0 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF3573 PF12097.8 KFO98659.1 - 0.076 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Chromo PF00385.24 KFO98659.1 - 0.1 12.5 0.2 0.36 10.8 0.0 2.1 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain EMP24_GP25L PF01105.24 KFO98660.1 - 4.1e-36 124.6 0.3 4.6e-36 124.5 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TSC22 PF01166.18 KFO98661.1 - 0.021 15.1 1.5 0.021 15.1 1.5 13.2 11 4 3 15 15 15 0 TSC-22/dip/bun family DUF3786 PF12654.7 KFO98661.1 - 0.21 11.2 5.7 0.17 11.5 1.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3786) adh_short PF00106.25 KFO98662.1 - 3.1e-37 127.9 0.0 1.5e-36 125.7 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFO98662.1 - 9.6e-23 81.0 0.0 3.4e-22 79.2 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFO98662.1 - 1.5e-08 34.8 0.0 2.3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 KFO98662.1 - 0.00049 19.8 0.0 0.0076 16.0 0.0 2.2 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GDP_Man_Dehyd PF16363.5 KFO98662.1 - 0.0024 17.3 0.0 0.0046 16.4 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF3015 PF11220.8 KFO98662.1 - 0.15 11.9 0.1 0.99 9.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3015) CBFD_NFYB_HMF PF00808.23 KFO98663.1 - 8.2e-24 83.7 1.9 1.8e-23 82.6 0.8 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFO98663.1 - 3.1e-05 24.3 0.0 4.1e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-W PF15510.6 KFO98663.1 - 0.00038 20.6 0.1 0.00051 20.2 0.1 1.1 1 0 0 1 1 1 1 CENP-W protein AAA_32 PF13654.6 KFO98663.1 - 0.011 14.5 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain RexA PF15969.5 KFO98663.1 - 0.022 14.3 0.0 0.022 14.3 0.0 1.1 1 0 0 1 1 1 0 Intracellular sensor of Lambda phage, Abi component Bromo_TP PF07524.13 KFO98663.1 - 0.055 13.5 0.0 0.078 13.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated FCH PF00611.23 KFO98664.1 - 6.9e-20 71.1 1.9 2.5e-19 69.3 0.1 2.8 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KFO98664.1 - 1.3e-12 47.1 0.1 2.8e-12 46.0 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFO98664.1 - 2.8e-11 43.1 0.0 6.6e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFO98664.1 - 1.1e-06 28.2 0.1 2.3e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFO98664.1 - 8.3e-05 22.8 0.1 0.00016 21.9 0.1 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain Lzipper-MIP1 PF14389.6 KFO98664.1 - 0.00093 19.5 1.5 0.0028 17.9 1.5 1.8 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 HR1 PF02185.16 KFO98664.1 - 0.0018 18.3 0.6 0.0018 18.3 0.6 3.5 3 0 0 3 3 3 1 Hr1 repeat COG5 PF10392.9 KFO98664.1 - 0.026 14.7 0.5 0.026 14.7 0.5 2.4 2 1 1 3 3 3 0 Golgi transport complex subunit 5 DUF4140 PF13600.6 KFO98664.1 - 0.18 12.3 8.0 0.59 10.6 0.2 3.1 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DEDD_Tnp_IS110 PF01548.17 KFO98664.1 - 0.22 11.4 5.3 0.062 13.2 0.9 2.3 3 0 0 3 3 3 0 Transposase Exonuc_VII_L PF02601.15 KFO98664.1 - 1.1 8.8 13.3 0.52 9.8 6.3 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit SH2 PF00017.24 KFO98665.1 - 1.6e-14 53.7 0.0 3.8e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 SH2 domain RasGEF PF00617.19 KFO98665.1 - 6.4e-13 49.3 0.0 1.6e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain Fcf2 PF08698.11 KFO98666.1 - 3.3e-38 130.0 0.4 3.3e-38 130.0 0.4 3.0 2 1 0 2 2 2 1 Fcf2 pre-rRNA processing MH1 PF03165.16 KFO98666.1 - 0.77 10.0 4.6 0.34 11.1 0.2 2.6 3 0 0 3 3 3 0 MH1 domain DUF3811 PF11656.8 KFO98666.1 - 0.86 10.0 6.4 1.1 9.7 2.7 3.0 2 0 0 2 2 2 0 YjbD family (DUF3811) Aldo_ket_red PF00248.21 KFO98667.1 - 1.9e-06 27.3 0.0 2.7e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family SHS2_FTSA PF02491.20 KFO98667.1 - 0.046 14.1 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 SHS2 domain inserted in FTSA Imm5 PF14423.6 KFO98667.1 - 0.08 13.2 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Immunity protein Imm5 Steroid_dh PF02544.16 KFO98668.1 - 2.6e-25 89.2 5.6 4.8e-25 88.3 5.6 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ABC_tran PF00005.27 KFO98669.1 - 1.6e-55 187.4 0.0 4.4e-30 105.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KFO98669.1 - 4.1e-54 184.0 30.6 1.1e-40 139.9 16.1 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KFO98669.1 - 1.8e-20 74.0 2.1 3.4e-08 33.7 0.1 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFO98669.1 - 0.0024 18.4 4.7 0.046 14.2 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFO98669.1 - 0.025 14.3 1.7 0.46 10.3 0.3 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 KFO98669.1 - 0.083 13.1 0.0 25 5.2 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 KFO98669.1 - 0.13 12.0 1.1 7.3 6.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KFO98669.1 - 0.19 11.4 5.2 3.1 7.4 0.5 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MukB PF04310.12 KFO98669.1 - 0.53 10.0 3.0 0.94 9.2 0.2 2.4 2 0 0 2 2 2 0 MukB N-terminal ABC_membrane_2 PF06472.15 KFO98670.1 - 5.3e-97 324.4 5.6 7e-97 324.0 5.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KFO98670.1 - 5.3e-18 65.9 0.0 1.2e-17 64.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 KFO98670.1 - 0.0004 21.0 0.0 0.0014 19.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KFO98670.1 - 0.0015 18.0 0.0 0.27 10.6 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFO98670.1 - 0.0094 15.8 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFO98670.1 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 KFO98670.1 - 0.032 14.2 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_27 PF13514.6 KFO98670.1 - 0.045 13.3 0.0 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Lon_2 PF13337.6 KFO98670.1 - 0.096 11.2 0.0 0.18 10.3 0.0 1.3 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease AAA_16 PF13191.6 KFO98670.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KFO98670.1 - 0.13 12.8 0.0 0.3 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KFO98670.1 - 0.16 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 KFO98670.1 - 0.16 11.9 0.0 0.43 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Interfer-bind PF09294.10 KFO98671.1 - 5.4e-19 68.4 0.5 5.4e-19 68.4 0.5 1.6 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.17 KFO98671.1 - 1.2e-17 63.7 1.0 1.7e-17 63.2 0.2 1.6 2 0 0 2 2 2 1 Tissue factor Sarcoglycan_2 PF05510.13 KFO98671.1 - 0.25 10.1 1.6 0.44 9.3 0.6 1.9 2 1 0 2 2 2 0 Sarcoglycan alpha/epsilon RVT_1 PF00078.27 KFO98672.1 - 0.04 13.4 0.0 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Choline_transpo PF04515.12 KFO98673.1 - 2.7e-88 296.3 33.5 2.7e-88 296.3 33.5 2.6 2 1 1 3 3 3 1 Plasma-membrane choline transporter TraA PF05513.11 KFO98673.1 - 0.14 12.5 1.1 0.94 9.8 0.0 2.6 2 0 0 2 2 2 0 TraA DUF3671 PF12420.8 KFO98673.1 - 3.9 7.6 7.8 0.26 11.4 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function Calponin PF00402.18 KFO98674.1 - 1.9e-44 148.9 16.5 4.8e-16 58.1 1.5 3.5 3 0 0 3 3 3 3 Calponin family repeat CH PF00307.31 KFO98674.1 - 5.4e-23 81.3 0.1 8e-23 80.7 0.1 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Raf1_HTH PF18579.1 KFO98674.1 - 0.15 11.8 0.0 0.52 10.0 0.0 2.0 2 0 0 2 2 2 0 Rubisco accumulation factor 1 helix turn helix domain CAMSAP_CH PF11971.8 KFO98674.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain Alg14 PF08660.11 KFO98675.1 - 7.1e-64 214.9 0.1 8e-64 214.8 0.1 1.0 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like TRAM_LAG1_CLN8 PF03798.16 KFO98676.1 - 2.8e-36 125.1 14.1 4.1e-36 124.6 14.1 1.2 1 0 0 1 1 1 1 TLC domain Cyto_heme_lyase PF01265.17 KFO98677.1 - 1e-70 238.7 19.5 1.1e-69 235.2 19.5 2.3 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase RWD PF05773.22 KFO98678.1 - 1.2e-13 51.4 0.2 2.8e-13 50.2 0.2 1.6 1 0 0 1 1 1 1 RWD domain DUF1115 PF06544.12 KFO98678.1 - 7e-07 29.4 1.3 0.00048 20.2 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1115) RRM_5 PF13893.6 KFO98679.1 - 3.4e-53 178.5 2.2 7.6e-40 135.4 0.0 4.1 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KFO98679.1 - 4.1e-32 109.8 0.2 1.9e-08 34.0 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KFO98679.1 - 1.7e-16 60.2 0.0 2.9e-15 56.3 0.0 2.4 2 0 0 2 2 2 1 RRM-like domain RRM_occluded PF16842.5 KFO98679.1 - 1.3e-09 37.8 0.2 0.072 13.0 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif DHO_dh PF01180.21 KFO98680.1 - 2.3e-33 115.7 0.0 9.5e-33 113.7 0.0 2.0 2 1 0 2 2 2 1 Dihydroorotate dehydrogenase Fer4_20 PF14691.6 KFO98680.1 - 1.8e-28 98.5 0.9 1.8e-28 98.5 0.9 2.3 3 0 0 3 3 2 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_21 PF14697.6 KFO98680.1 - 4.8e-24 84.3 12.3 4.8e-24 84.3 12.3 3.7 3 1 0 3 3 3 1 4Fe-4S dicluster domain Pyr_redox_2 PF07992.14 KFO98680.1 - 6.2e-14 51.9 0.0 2e-13 50.2 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFO98680.1 - 6.6e-08 32.7 0.0 1.7e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KFO98680.1 - 3.5e-06 26.5 0.0 0.015 14.6 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Dus PF01207.17 KFO98680.1 - 5.9e-06 25.6 0.1 0.00013 21.2 0.1 2.1 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Fer4_7 PF12838.7 KFO98680.1 - 2e-05 25.1 10.3 2e-05 25.1 10.3 3.6 4 0 0 4 4 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KFO98680.1 - 2.5e-05 24.3 24.8 0.00014 21.9 10.1 3.1 2 2 0 2 2 2 2 4Fe-4S dicluster domain Pyr_redox PF00070.27 KFO98680.1 - 7.5e-05 23.2 0.9 0.69 10.5 0.0 3.4 3 1 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_6 PF12837.7 KFO98680.1 - 0.00033 20.6 1.8 0.00033 20.6 1.8 4.5 4 1 1 5 5 5 2 4Fe-4S binding domain Fer4_9 PF13187.6 KFO98680.1 - 0.00047 20.3 24.7 0.0013 18.8 11.8 2.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KFO98680.1 - 0.0014 18.6 12.8 0.0028 17.6 2.3 4.7 5 0 0 5 5 4 2 4Fe-4S binding domain Fer4 PF00037.27 KFO98680.1 - 0.0065 16.3 4.6 0.0065 16.3 4.6 5.5 6 0 0 6 6 6 2 4Fe-4S binding domain Thi4 PF01946.17 KFO98680.1 - 0.014 14.6 0.0 0.035 13.4 0.0 1.6 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 KFO98680.1 - 0.064 12.8 0.0 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KFO98680.1 - 0.15 12.1 0.0 23 5.0 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KFO98680.1 - 0.18 10.8 0.8 1.5 7.8 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain MCRA PF06100.11 KFO98680.1 - 0.2 10.4 0.0 0.32 9.7 0.0 1.2 1 0 0 1 1 1 0 MCRA family PX PF00787.24 KFO98681.1 - 4.5e-26 91.0 1.7 9.8e-26 90.0 0.6 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 KFO98681.1 - 0.0013 18.3 6.5 0.047 13.2 2.6 2.5 2 1 0 2 2 2 1 Vps5 C terminal like NuA4 PF09340.10 KFO98681.1 - 0.064 13.1 0.1 0.26 11.2 0.1 2.0 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 PAP2 PF01569.21 KFO98682.1 - 3e-22 78.8 2.9 4e-22 78.4 2.9 1.2 1 0 0 1 1 1 1 PAP2 superfamily Cyt_bd_oxida_II PF02322.15 KFO98682.1 - 0.022 14.1 0.8 0.032 13.6 0.8 1.2 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II Tim17 PF02466.19 KFO98682.1 - 0.083 13.3 0.1 0.14 12.5 0.1 1.4 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family MtrF PF09472.10 KFO98682.1 - 0.2 11.1 0.8 0.41 10.1 0.8 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) PAP2 PF01569.21 KFO98683.1 - 2.5e-17 62.9 1.3 3.9e-17 62.3 1.3 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KFO98683.1 - 0.073 12.7 0.3 0.12 12.0 0.3 1.4 1 0 0 1 1 1 0 PAP2 superfamily Paralemmin PF03285.15 KFO98684.1 - 4.9e-56 190.6 22.7 9.2e-55 186.4 22.7 2.3 1 1 0 1 1 1 1 Paralemmin Mu-like_Pro PF10123.9 KFO98684.1 - 0.1 12.2 6.9 0.19 11.2 6.9 1.4 1 0 0 1 1 1 0 Mu-like prophage I protein PilJ PF13675.6 KFO98684.1 - 0.11 12.5 1.2 0.27 11.2 1.2 1.7 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term ADK PF00406.22 KFO98684.1 - 0.5 10.5 3.9 1.5 8.9 3.6 1.9 2 0 0 2 2 2 0 Adenylate kinase FlaC_arch PF05377.11 KFO98684.1 - 0.54 10.7 6.3 4.8 7.7 6.3 2.7 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 KFO98684.1 - 5.5 6.3 7.0 11 5.3 7.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Reeler PF02014.16 KFO98685.1 - 1.1e-29 103.8 0.0 1.8e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 Reeler domain DOMON PF03351.17 KFO98685.1 - 1.6e-17 63.9 0.0 3.4e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 KFO98685.1 - 2.3e-05 24.5 7.6 5.3e-05 23.4 7.6 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Claudin_3 PF06653.11 KFO98685.1 - 0.12 12.4 6.1 0.16 11.9 3.5 2.2 1 1 1 2 2 2 0 Tight junction protein, Claudin-like hDGE_amylase PF14701.6 KFO98686.1 - 5.6e-164 546.4 0.2 7.5e-164 546.0 0.2 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KFO98686.1 - 3.6e-133 444.2 0.0 5.8e-133 443.5 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KFO98686.1 - 5.1e-77 259.0 0.0 8e-77 258.3 0.0 1.3 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KFO98686.1 - 9.1e-21 73.8 0.0 1.8e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 KFO98686.1 - 1.5e-05 24.7 0.0 4.8e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Nuc_sug_transp PF04142.15 KFO98687.1 - 4.4e-139 463.0 18.8 5e-139 462.8 18.8 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KFO98687.1 - 2.6e-07 30.9 30.9 9.3e-06 25.9 3.2 2.6 3 0 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 KFO98687.1 - 7.8e-07 28.6 9.9 7.8e-07 28.6 9.9 2.2 1 1 1 2 2 2 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 KFO98687.1 - 6.2e-06 25.4 2.6 6.2e-06 25.4 2.6 1.7 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 KFO98687.1 - 1.5e-05 24.3 14.6 1.7e-05 24.2 13.5 1.5 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.6 KFO98687.1 - 6.7e-05 22.6 9.0 9.5e-05 22.1 1.5 2.3 2 0 0 2 2 2 2 Putative multidrug resistance efflux transporter DUF202 PF02656.15 KFO98687.1 - 0.025 15.0 0.7 0.025 15.0 0.7 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF202) Aim19 PF10315.9 KFO98687.1 - 0.08 13.2 2.0 0.49 10.7 0.2 2.6 1 1 0 2 2 2 0 Altered inheritance of mitochondria protein 19 MFS_1 PF07690.16 KFO98688.1 - 8e-34 117.1 38.1 2.1e-32 112.4 37.8 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KFO98688.1 - 1.3e-11 44.0 21.9 1.2e-09 37.5 21.9 2.9 1 1 0 1 1 1 1 MFS_1 like family CCB1 PF12046.8 KFO98688.1 - 1.8 7.9 4.4 1.4 8.2 1.3 2.3 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B SAS-6_N PF16531.5 KFO98689.1 - 1.3e-28 99.3 2.7 8.4e-28 96.8 2.7 2.5 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal Sas6_CC PF18594.1 KFO98689.1 - 6e-14 51.5 7.3 6e-14 51.5 7.3 4.1 5 0 0 5 5 5 1 Sas6/XLF/XRCC4 coiled-coil domain Tropomyosin_1 PF12718.7 KFO98689.1 - 0.011 15.9 15.1 0.011 15.9 15.1 4.9 1 1 4 5 5 5 0 Tropomyosin like DUF641 PF04859.12 KFO98689.1 - 0.012 16.0 7.9 0.012 16.0 7.9 5.3 1 1 3 4 4 4 0 Plant protein of unknown function (DUF641) PI3K_P85_iSH2 PF16454.5 KFO98689.1 - 0.74 9.4 64.9 0.51 9.9 28.4 4.1 1 1 2 4 4 4 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Spc7 PF08317.11 KFO98689.1 - 1.2 7.9 77.7 0.57 9.0 28.0 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein ATG16 PF08614.11 KFO98689.1 - 4.6 7.4 72.7 0.16 12.2 8.9 4.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) HrpB7 PF09486.10 KFO98689.1 - 8.3 6.8 35.9 2.1 8.7 20.3 3.6 2 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) TRM13 PF05206.14 KFO98690.1 - 1.1e-90 303.7 3.2 1.6e-90 303.2 3.2 1.2 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 KFO98690.1 - 1.8e-12 46.8 3.1 1.8e-12 46.8 3.1 2.4 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.12 KFO98690.1 - 2.9e-11 43.0 1.9 6.6e-11 41.9 1.9 1.7 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger LRR_8 PF13855.6 KFO98691.1 - 8.4e-32 108.7 23.2 2e-09 37.0 1.4 3.9 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFO98691.1 - 2.4e-26 91.4 31.9 7.3e-07 29.4 0.1 5.4 2 1 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFO98691.1 - 1.6e-06 27.8 18.3 10 7.1 0.0 8.6 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_9 PF14580.6 KFO98691.1 - 1.7e-06 27.7 9.6 0.0038 16.8 1.5 2.8 1 1 2 3 3 3 2 Leucine-rich repeat SPATA19 PF15212.6 KFO98691.1 - 0.052 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Spermatogenesis-associated protein 19, mitochondrial CREPT PF16566.5 KFO98691.1 - 0.19 11.9 4.6 11 6.1 0.0 4.0 2 1 1 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour LRR_6 PF13516.6 KFO98691.1 - 0.36 11.0 23.5 20 5.6 0.1 7.4 9 0 0 9 9 9 0 Leucine Rich repeat 2-oxoacid_dh PF00198.23 KFO98692.1 - 1.4e-78 263.5 0.0 2.1e-78 263.0 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFO98692.1 - 1.1e-17 63.6 0.1 1.9e-17 62.8 0.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KFO98692.1 - 1.2e-14 54.4 0.1 3e-14 53.1 0.1 1.8 1 0 0 1 1 1 1 e3 binding domain Toprim_Crpt PF13342.6 KFO98692.1 - 0.095 12.7 0.1 0.75 9.8 0.0 2.2 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase RTC PF01137.21 KFO98693.1 - 1.2e-79 266.6 0.1 1.6e-79 266.2 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KFO98693.1 - 4.8e-23 81.6 0.1 8.6e-23 80.8 0.1 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain 7tm_1 PF00001.21 KFO98694.1 - 1.5e-15 57.3 0.4 1.9e-15 56.9 0.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFO98694.1 - 3.4e-10 40.0 1.1 4.7e-10 39.5 1.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFO98694.1 - 0.0034 16.8 1.1 0.0048 16.3 1.1 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx MtrF PF09472.10 KFO98694.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DSPn PF14671.6 KFO98695.1 - 1.3e-61 207.1 2.9 5.9e-61 205.0 1.8 2.5 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KFO98695.1 - 1.2e-14 54.2 0.1 5.5e-14 52.1 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFO98695.1 - 2.6e-06 27.6 0.0 5.8e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KFO98695.1 - 5.5e-05 22.8 0.0 8.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFO98695.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Glyco_transf_64 PF09258.10 KFO98696.1 - 6.6e-87 290.8 0.0 7.8e-87 290.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_tranf_2_3 PF13641.6 KFO98696.1 - 0.0013 18.7 0.0 0.0018 18.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KFO98696.1 - 0.013 15.4 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 TP_methylase PF00590.20 KFO98697.1 - 6.7e-23 81.7 0.0 1.3e-22 80.8 0.0 1.5 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF4062 PF13271.6 KFO98697.1 - 0.16 12.4 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) PAS_8 PF13188.7 KFO98697.1 - 0.17 12.0 0.0 0.42 10.7 0.0 1.6 1 0 0 1 1 1 0 PAS domain Neur PF00064.18 KFO98698.1 - 0.099 11.4 0.0 0.11 11.3 0.0 1.0 1 0 0 1 1 1 0 Neuraminidase rve PF00665.26 KFO98699.1 - 4.5e-28 97.8 0.2 9.3e-28 96.8 0.2 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_Zn PF02022.19 KFO98699.1 - 4.5e-12 45.7 0.4 1.1e-11 44.4 0.4 1.7 2 0 0 2 2 2 1 Integrase Zinc binding domain RNase_H PF00075.24 KFO98699.1 - 3.8e-10 40.1 0.0 1.1e-09 38.7 0.0 1.7 2 0 0 2 2 2 1 RNase H DDE_Tnp_IS240 PF13610.6 KFO98699.1 - 0.0043 17.3 0.0 0.0075 16.5 0.0 1.4 1 0 0 1 1 1 1 DDE domain UCR_UQCRX_QCR9 PF05365.12 KFO98699.1 - 0.006 16.5 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like rve_3 PF13683.6 KFO98699.1 - 0.013 15.2 0.0 0.073 12.9 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain dUTPase PF00692.19 KFO98700.1 - 2.6e-18 66.0 0.0 3.8e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 dUTPase RVP PF00077.20 KFO98700.1 - 5.2e-05 23.5 0.4 0.00019 21.7 0.1 2.1 2 2 1 3 3 3 1 Retroviral aspartyl protease Peptidase_U4 PF03419.13 KFO98700.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA OLF PF02191.16 KFO98701.1 - 5.9e-83 278.2 9.1 8.3e-83 277.7 9.1 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain Noelin-1 PF12308.8 KFO98701.1 - 3.3e-49 165.0 1.7 3.3e-49 165.0 1.7 2.2 3 0 0 3 3 3 1 Neurogenesis glycoprotein Dynactin_p22 PF07426.11 KFO98701.1 - 0.17 11.8 7.8 0.15 11.9 5.9 1.9 1 1 0 1 1 1 0 Dynactin subunit p22 Csm2_III-A PF03750.13 KFO98701.1 - 0.25 12.2 3.4 0.53 11.1 3.4 1.6 1 0 0 1 1 1 0 Csm2 Type III-A DUF1664 PF07889.12 KFO98701.1 - 0.85 9.7 5.2 3.8 7.6 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Phage_head_chap PF11113.8 KFO98701.1 - 3.2 7.9 5.4 31 4.8 0.0 3.7 4 0 0 4 4 4 0 Head assembly gene product Collagen PF01391.18 KFO98702.1 - 3.2e-156 507.2 668.5 6.4e-10 38.7 23.1 22.0 5 3 11 16 16 16 14 Collagen triple helix repeat (20 copies) COLFI PF01410.18 KFO98702.1 - 8.2e-98 326.4 0.1 1.3e-97 325.7 0.1 1.3 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Laminin_G_2 PF02210.24 KFO98702.1 - 7.5e-05 23.3 0.0 0.00014 22.5 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.6 KFO98702.1 - 0.00039 20.6 0.0 0.00063 19.9 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_1 PF00054.23 KFO98702.1 - 0.0069 16.6 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain MAJIN PF15077.6 KFO98702.1 - 0.47 10.2 3.8 0.76 9.5 3.8 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein HSR PF03172.13 KFO98703.1 - 5.5e-22 77.8 0.0 7.6e-22 77.3 0.0 1.2 1 0 0 1 1 1 1 HSR domain PHD PF00628.29 KFO98703.1 - 8e-09 35.3 9.4 8e-09 35.3 9.4 1.8 2 0 0 2 2 2 1 PHD-finger Aminotran_5 PF00266.19 KFO98704.1 - 1.9e-35 122.5 0.0 2.7e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V EamA PF00892.20 KFO98705.1 - 2.4e-17 63.4 30.3 1e-08 35.4 16.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family IRK PF01007.20 KFO98706.1 - 4.4e-47 159.4 0.1 8.7e-47 158.5 0.1 1.5 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain IRK_C PF17655.1 KFO98706.1 - 2.1e-34 118.7 0.0 2.9e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain Ion_trans_2 PF07885.16 KFO98706.1 - 0.00014 21.7 3.2 0.0003 20.7 3.2 1.6 1 1 0 1 1 1 1 Ion channel DUF4690 PF15756.5 KFO98707.1 - 4.1e-43 145.9 0.2 4.6e-43 145.7 0.2 1.0 1 0 0 1 1 1 1 Small Novel Rich in Cartilage RhoGEF PF00621.20 KFO98708.1 - 1.3e-34 120.0 8.8 2.2e-34 119.3 8.8 1.4 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.6 KFO98708.1 - 1.9e-12 46.8 0.1 4.1e-12 45.8 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFO98708.1 - 2.3e-12 46.3 0.0 6.5e-12 44.9 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFO98708.1 - 5.4e-07 29.2 0.0 1.2e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 KFO98708.1 - 9.5e-06 26.1 0.4 0.00011 22.7 0.0 2.7 3 0 0 3 3 3 1 PH domain SH3_16 PF18348.1 KFO98708.1 - 0.045 13.6 0.1 0.38 10.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain SesA PF17107.5 KFO98708.1 - 0.055 13.7 0.6 0.055 13.7 0.6 2.1 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases BNR_2 PF13088.6 KFO98709.1 - 4.7e-37 127.8 0.0 5.9e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 KFO98709.1 - 0.00075 19.1 4.7 0.21 11.7 0.2 3.7 4 0 0 4 4 4 2 BNR/Asp-box repeat ATG16 PF08614.11 KFO98710.1 - 2.8e-42 145.2 26.7 2.8e-42 145.2 26.7 2.0 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) WD40 PF00400.32 KFO98710.1 - 8.6e-35 118.2 12.1 1.1e-06 29.2 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO98710.1 - 1.1e-09 38.5 0.1 0.0051 17.1 0.0 4.8 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFO98710.1 - 1.7e-05 23.9 0.2 0.4 9.6 0.2 3.4 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFO98710.1 - 4.2e-05 23.5 0.0 1.6 8.6 0.0 3.5 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KFO98710.1 - 0.00046 19.0 8.1 1.5 7.4 0.0 4.3 3 1 1 5 5 5 3 Nucleoporin Nup120/160 Fez1 PF06818.15 KFO98710.1 - 0.0043 17.5 26.4 0.0077 16.7 26.4 1.3 1 0 0 1 1 1 1 Fez1 ZapB PF06005.12 KFO98710.1 - 0.0086 16.5 8.4 0.0086 16.5 8.4 3.8 1 1 2 3 3 3 1 Cell division protein ZapB KASH_CCD PF14662.6 KFO98710.1 - 0.015 15.1 12.9 0.015 15.1 12.9 2.9 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH V_ATPase_I PF01496.19 KFO98710.1 - 0.022 12.7 11.2 0.028 12.4 11.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ERM PF00769.19 KFO98710.1 - 0.041 13.7 32.1 0.026 14.3 30.1 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family HTH_6 PF01418.17 KFO98710.1 - 0.058 13.4 1.0 0.16 12.0 1.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Lipoprotein_6 PF01441.19 KFO98710.1 - 0.068 13.2 4.8 0.13 12.3 4.5 1.6 1 1 0 1 1 1 0 Lipoprotein WD40_like PF17005.5 KFO98710.1 - 0.078 12.3 0.0 0.53 9.6 0.0 2.3 3 1 0 3 3 3 0 WD40-like domain SGL PF08450.12 KFO98710.1 - 0.14 11.7 0.0 0.53 9.8 0.0 1.9 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region YabA PF06156.13 KFO98710.1 - 0.3 11.7 20.6 0.18 12.4 7.6 2.7 1 1 1 2 2 2 0 Initiation control protein YabA YicC_N PF03755.13 KFO98710.1 - 0.54 10.7 9.0 1.1 9.7 9.0 1.5 1 0 0 1 1 1 0 YicC-like family, N-terminal region Synaptobrevin PF00957.21 KFO98710.1 - 0.83 9.5 5.5 3 7.7 4.9 2.2 2 0 0 2 2 2 0 Synaptobrevin Atg14 PF10186.9 KFO98710.1 - 1.4 7.9 15.4 2.8 6.9 15.4 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 NPV_P10 PF05531.12 KFO98710.1 - 1.5 9.4 5.1 0.74 10.3 0.7 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Lebercilin PF15619.6 KFO98710.1 - 1.7 8.3 34.8 3.2 7.4 34.8 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF812 PF05667.11 KFO98710.1 - 1.7 7.4 26.7 2.4 6.9 26.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) MRP-S27 PF10037.9 KFO98710.1 - 1.9 7.2 18.4 2.9 6.7 18.4 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 FUSC PF04632.12 KFO98710.1 - 2.2 6.7 11.9 3 6.3 11.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 KFO98710.1 - 2.6 8.1 8.0 14 5.8 8.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Allexi_40kDa PF05549.11 KFO98710.1 - 2.8 7.4 8.4 4 6.9 7.2 1.7 1 1 0 1 1 1 0 Allexivirus 40kDa protein Phage_GPO PF05929.11 KFO98710.1 - 3.2 7.3 17.1 2.3 7.8 14.3 2.1 1 1 2 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase APG6_N PF17675.1 KFO98710.1 - 3.9 8.0 41.1 3 8.4 20.0 3.0 1 1 2 3 3 3 0 Apg6 coiled-coil region BLOC1_2 PF10046.9 KFO98710.1 - 4.1 7.8 17.0 8.7 6.7 1.2 3.1 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TSC22 PF01166.18 KFO98710.1 - 4.2 7.8 8.9 1.4 9.3 1.8 3.0 1 1 2 3 3 3 0 TSC-22/dip/bun family FlaC_arch PF05377.11 KFO98710.1 - 4.7 7.7 8.9 0.25 11.8 1.6 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) PKcGMP_CC PF16808.5 KFO98710.1 - 6.8 6.6 11.7 0.3 11.0 2.1 3.2 2 1 1 3 3 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HALZ PF02183.18 KFO98710.1 - 8.1 6.8 13.3 0.35 11.1 5.0 3.2 2 2 1 3 3 2 0 Homeobox associated leucine zipper FapA PF03961.13 KFO98710.1 - 8.2 4.9 19.5 1.8 7.1 15.1 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF724 PF05266.14 KFO98710.1 - 8.3 6.2 21.4 0.19 11.5 13.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Arrestin_N PF00339.29 KFO98711.1 - 1e-38 132.7 0.1 4.1e-35 121.0 0.0 2.4 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KFO98711.1 - 2.1e-25 89.7 0.5 3e-25 89.2 0.5 1.2 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain DUF2079 PF09852.9 KFO98711.1 - 0.0029 16.5 0.0 0.0039 16.1 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2079) Transglut_C PF00927.22 KFO98711.1 - 0.035 14.2 0.1 0.074 13.2 0.1 1.5 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain LDB19 PF13002.7 KFO98711.1 - 0.088 12.5 0.0 10 5.8 0.0 2.2 2 0 0 2 2 2 0 Arrestin_N terminal like DAGK_acc PF00609.19 KFO98712.1 - 2.3e-51 174.3 0.0 4.7e-51 173.3 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KFO98712.1 - 2e-27 95.3 0.1 5.4e-27 93.9 0.0 1.8 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 KFO98712.1 - 1.2e-18 66.8 28.2 8.5e-11 41.6 4.9 2.9 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 KFO98712.1 - 2.7e-15 56.7 1.3 7e-15 55.4 0.2 2.2 2 0 0 2 2 2 1 PH domain SAM_2 PF07647.17 KFO98712.1 - 3e-12 46.4 0.6 1.9e-11 43.9 0.1 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFO98712.1 - 1.9e-11 44.2 1.6 1.9e-10 41.1 0.3 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH_8 PF15409.6 KFO98712.1 - 0.00017 21.8 0.2 0.00039 20.7 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFO98712.1 - 0.00026 21.4 2.5 0.0056 17.1 2.5 3.2 1 1 0 1 1 1 1 Pleckstrin homology domain C1_2 PF03107.16 KFO98712.1 - 0.0017 18.6 16.0 0.014 15.7 5.7 3.0 2 0 0 2 2 2 2 C1 domain Mcp5_PH PF12814.7 KFO98712.1 - 0.02 15.0 0.1 0.051 13.7 0.1 1.7 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Trypsin PF00089.26 KFO98713.1 - 7.2e-63 212.3 0.0 8e-63 212.2 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFO98713.1 - 6.9e-08 32.9 0.1 1.9e-07 31.5 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 KFO98713.1 - 4.7e-05 24.3 0.0 8e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain Carboxyl_trans PF01039.22 KFO98714.1 - 3e-139 464.9 0.0 3.3e-139 464.7 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MSL2-CXC PF16682.5 KFO98715.1 - 2.9e-19 68.9 20.3 5.5e-19 68.0 20.3 1.4 1 0 0 1 1 1 1 CXC domain of E3 ubiquitin-protein ligase MSL2 EF-hand_13 PF17958.1 KFO98716.1 - 1.3e-40 137.1 0.0 2.2e-39 133.2 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 KFO98716.1 - 2.9e-21 75.7 5.0 3.7e-20 72.2 0.5 3.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 KFO98716.1 - 1.6e-05 24.1 0.0 0.0008 18.8 0.0 2.9 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 KFO98716.1 - 0.00019 20.8 0.1 0.064 12.8 0.1 4.2 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.6 KFO98716.1 - 0.00022 20.9 2.2 0.036 14.0 0.0 4.3 4 0 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.6 KFO98716.1 - 0.00026 20.8 0.1 1 9.2 0.0 4.0 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFO98716.1 - 0.025 14.9 1.4 6.9 7.0 0.3 2.6 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DBR1 PF05011.13 KFO98717.1 - 1.9e-35 122.3 0.1 3.5e-35 121.5 0.1 1.5 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KFO98717.1 - 1.8e-10 41.6 0.3 3e-10 40.9 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFO98717.1 - 0.002 18.4 0.0 0.0054 16.9 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Arm PF00514.23 KFO98718.1 - 1.8e-21 75.4 21.5 0.00019 21.4 0.2 11.3 12 0 0 12 12 12 5 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KFO98718.1 - 1.9e-10 40.1 18.6 0.032 14.5 0.1 8.5 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.6 KFO98718.1 - 3.2e-08 33.9 7.3 0.0096 16.4 0.1 6.9 7 1 2 9 9 9 2 HEAT-like repeat V-ATPase_H_C PF11698.8 KFO98718.1 - 6.8e-07 29.4 9.8 0.23 11.6 0.0 5.9 4 2 2 6 6 6 3 V-ATPase subunit H Uso1_p115_head PF04869.14 KFO98718.1 - 0.0019 17.4 3.4 1.1 8.4 0.1 3.9 3 1 1 4 4 4 1 Uso1 / p115 like vesicle tethering protein, head region ParcG PF10274.9 KFO98718.1 - 0.007 16.5 2.7 0.97 9.5 0.3 3.7 2 1 0 3 3 3 1 Parkin co-regulated protein Cnd1 PF12717.7 KFO98718.1 - 0.039 14.0 16.4 0.47 10.5 0.9 4.7 2 2 2 5 5 5 0 non-SMC mitotic condensation complex subunit 1 RasGEF_N_2 PF14663.6 KFO98718.1 - 0.47 10.9 7.3 13 6.3 0.1 5.0 4 3 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RTTN_N PF14726.6 KFO98718.1 - 2.5 9.0 8.3 75 4.2 0.0 4.8 2 1 1 4 4 4 0 Rotatin, an armadillo repeat protein, centriole functioning UNC45-central PF11701.8 KFO98718.1 - 2.6 8.0 15.5 8.8 6.3 0.4 4.7 2 1 3 5 5 5 0 Myosin-binding striated muscle assembly central DUF3361 PF11841.8 KFO98718.1 - 6.3 6.7 20.0 2.1 8.2 2.2 4.6 2 2 3 5 5 5 0 Domain of unknown function (DUF3361) Thioredoxin PF00085.20 KFO98719.1 - 5.7e-06 26.2 0.0 6.4e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin UPF0524 PF15823.5 KFO98720.1 - 3.4e-84 282.0 4.6 3.8e-84 281.8 4.6 1.0 1 0 0 1 1 1 1 UPF0524 of C3orf70 3HCDH_N PF02737.18 KFO98721.1 - 1.2e-52 178.4 0.7 1.6e-52 178.0 0.7 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KFO98721.1 - 1.8e-28 99.0 0.0 5e-25 88.0 0.0 3.0 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KFO98721.1 - 0.0013 18.9 0.1 0.0039 17.4 0.1 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 KFO98721.1 - 0.01 16.1 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.17 KFO98721.1 - 0.016 15.8 0.1 0.038 14.6 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ECH_1 PF00378.20 KFO98722.1 - 6.4e-35 120.7 0.1 7.2e-35 120.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFO98722.1 - 1.6e-24 87.1 0.1 2.6e-24 86.3 0.1 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KFO98722.1 - 2.3e-05 24.4 0.0 0.13 12.2 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S49 Pkinase_Tyr PF07714.17 KFO98723.1 - 2.8e-64 216.9 0.0 4.3e-64 216.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO98723.1 - 2.5e-59 200.8 0.0 4.8e-59 199.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KFO98723.1 - 0.001 17.9 0.1 0.0029 16.4 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase DUF737 PF05300.11 KFO98723.1 - 0.023 15.1 0.4 0.023 15.1 0.4 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF737) APH PF01636.23 KFO98723.1 - 0.076 12.9 0.0 2 8.3 0.0 2.8 3 0 0 3 3 3 0 Phosphotransferase enzyme family SNARE_assoc PF09335.11 KFO98725.1 - 1.8e-19 70.4 3.7 1.8e-19 70.4 3.7 1.4 2 0 0 2 2 2 1 SNARE associated Golgi protein Sm_multidrug_ex PF06695.11 KFO98725.1 - 0.16 12.6 1.9 0.18 12.5 0.8 1.7 1 1 0 1 1 1 0 Putative small multi-drug export protein Lipase PF00151.19 KFO98726.1 - 1.7e-82 277.4 0.0 2.3e-82 277.0 0.0 1.1 1 0 0 1 1 1 1 Lipase Apc13p PF05839.11 KFO98727.1 - 3.6e-20 71.9 0.3 5e-20 71.5 0.3 1.2 1 0 0 1 1 1 1 Apc13p protein CEP63 PF17045.5 KFO98728.1 - 1.7e-105 352.8 58.6 1.7e-105 352.8 58.6 4.8 4 1 1 5 5 5 2 Centrosomal protein of 63 kDa DUF4407 PF14362.6 KFO98728.1 - 8.6 5.6 72.4 0.021 14.2 5.6 4.7 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) Transglut_core PF01841.19 KFO98729.1 - 1.3e-12 48.2 0.0 2.5e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Pkinase_Tyr PF07714.17 KFO98730.1 - 2.9e-100 334.8 0.0 3.4e-100 334.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO98730.1 - 1.2e-50 172.3 0.0 1.5e-50 172.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.6 KFO98730.1 - 1.3e-13 51.6 1.0 2.4e-13 50.8 1.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Haspin_kinase PF12330.8 KFO98730.1 - 0.0044 16.0 0.0 0.007 15.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain ABC1 PF03109.16 KFO98730.1 - 0.011 15.9 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Kdo PF06293.14 KFO98730.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFO98730.1 - 0.15 10.8 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Gb3_synth PF04572.12 KFO98731.1 - 8.6e-46 155.3 1.3 1.3e-45 154.7 1.3 1.3 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.15 KFO98731.1 - 2e-19 70.0 0.0 5.6e-19 68.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif PMP22_Claudin PF00822.20 KFO98732.1 - 2.4e-30 105.6 14.0 3.2e-30 105.2 14.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFO98732.1 - 2e-12 47.3 15.6 6.2e-11 42.4 15.6 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Trp_oprn_chp PF09534.10 KFO98732.1 - 0.0037 17.1 1.7 0.081 12.7 1.7 2.3 1 1 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Amastin PF07344.11 KFO98732.1 - 0.38 10.6 11.3 0.28 11.0 9.5 1.7 1 1 0 1 1 1 0 Amastin surface glycoprotein DUF308 PF03729.13 KFO98732.1 - 5 7.5 24.2 0.25 11.7 8.9 3.0 2 1 2 4 4 4 0 Short repeat of unknown function (DUF308) Phage_holin_3_6 PF07332.11 KFO98732.1 - 7.1 6.7 22.1 0.22 11.5 6.1 2.4 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III HMG_box PF00505.19 KFO98733.1 - 1.1e-28 99.4 5.0 1.1e-28 99.4 5.0 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFO98733.1 - 2e-12 47.5 2.9 3.6e-12 46.7 2.9 1.4 1 0 0 1 1 1 1 HMG-box domain SOXp PF12336.8 KFO98733.1 - 3.8e-07 31.1 1.3 5.1e-06 27.5 1.3 2.3 1 1 0 1 1 1 1 SOX transcription factor Crystall PF00030.19 KFO98734.1 - 2e-60 201.0 1.0 1.1e-29 102.4 0.1 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin IL4_i_Ig PF18258.1 KFO98734.1 - 4.7e-07 29.9 1.1 0.025 14.8 0.1 3.0 2 2 0 2 2 2 2 Interleukin-4 inducing immunoglobulin-binding domain Crystall_3 PF08964.10 KFO98734.1 - 0.00092 19.3 0.1 15 5.8 0.1 3.2 3 0 0 3 3 3 3 Beta/Gamma crystallin Inhibitor_I36 PF03995.13 KFO98734.1 - 0.0043 17.0 2.5 3.5 7.6 0.2 3.7 1 1 3 4 4 4 3 Peptidase inhibitor family I36 LPD18 PF18832.1 KFO98734.1 - 0.027 14.5 0.1 9 6.4 0.0 2.3 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 18 PMR5N PF14416.6 KFO98734.1 - 1.4 9.3 6.2 4 7.8 0.0 3.2 3 1 1 4 4 4 0 PMR5 N terminal Domain TBCC PF07986.12 KFO98735.1 - 6.3e-34 116.3 0.1 1.2e-33 115.3 0.1 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 KFO98735.1 - 1.8e-05 24.4 0.6 3.7e-05 23.4 0.6 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal DnaJ_C PF01556.18 KFO98736.1 - 5.4e-38 130.4 0.1 8.5e-38 129.7 0.1 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFO98736.1 - 1.2e-28 99.0 0.8 1.8e-28 98.4 0.8 1.3 1 0 0 1 1 1 1 DnaJ domain MHC_I_3 PF16497.5 KFO98737.1 - 2.4e-09 37.0 0.2 3.4e-09 36.5 0.2 1.1 1 0 0 1 1 1 1 MHC-I family domain MHC_I PF00129.18 KFO98737.1 - 4e-07 29.8 0.1 5.9e-07 29.2 0.1 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 PFK PF00365.20 KFO98738.1 - 4.7e-198 656.1 5.3 1.4e-101 339.6 0.6 2.1 2 0 0 2 2 2 2 Phosphofructokinase LRR_4 PF12799.7 KFO98739.1 - 2.2e-11 43.8 13.5 5.5e-07 29.8 4.2 3.5 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFO98739.1 - 1.8e-07 30.8 0.3 4.5e-07 29.5 0.3 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KFO98739.1 - 6.6e-06 25.8 3.9 0.00078 19.2 4.1 3.1 1 1 1 2 2 2 2 Leucine rich repeat SART-1 PF03343.13 KFO98739.1 - 1e-05 24.4 0.1 1.3e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 SART-1 family Cnd1 PF12717.7 KFO98739.1 - 0.12 12.4 0.3 0.27 11.3 0.2 1.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 LRR_6 PF13516.6 KFO98739.1 - 0.21 11.7 3.6 0.61 10.3 0.2 3.3 4 0 0 4 4 4 0 Leucine Rich repeat KH_1 PF00013.29 KFO98740.1 - 2.1e-57 190.8 12.2 6.4e-16 57.9 0.2 4.4 4 0 0 4 4 4 4 KH domain KH_2 PF07650.17 KFO98740.1 - 8.9e-17 60.7 7.9 0.00046 20.0 0.1 4.9 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 KFO98740.1 - 7.6e-16 57.7 1.8 0.0014 18.4 0.1 5.0 5 0 0 5 5 5 4 KH domain KH_5 PF13184.6 KFO98740.1 - 2.3e-07 30.8 3.0 0.44 10.7 0.1 4.6 4 0 0 4 4 4 3 NusA-like KH domain RRM_1 PF00076.22 KFO98740.1 - 2.5e-07 30.4 0.0 5.4e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MOEP19 PF16005.5 KFO98740.1 - 1.4e-05 25.0 0.1 0.088 12.8 0.0 4.0 4 0 0 4 4 4 1 KH-like RNA-binding domain RRM_5 PF13893.6 KFO98740.1 - 0.081 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SLS PF14611.6 KFO98740.1 - 0.9 9.3 5.8 2.8 7.7 0.1 3.6 4 1 1 5 5 5 0 Mitochondrial inner-membrane-bound regulator HMA PF00403.26 KFO98740.1 - 0.99 9.9 5.3 31 5.1 0.4 3.6 4 0 0 4 4 4 0 Heavy-metal-associated domain Peptidase_C48 PF02902.19 KFO98741.1 - 1e-41 143.2 1.6 1.4e-41 142.7 1.6 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.13 KFO98741.1 - 2.7e-05 23.1 0.4 0.00091 18.0 0.0 2.1 2 0 0 2 2 2 2 Vaccinia virus I7 processing peptidase Angiomotin_C PF12240.8 KFO98742.1 - 2e-94 315.0 10.4 2e-94 315.0 10.4 4.1 2 1 2 4 4 4 1 Angiomotin C terminal DctP PF03480.13 KFO98742.1 - 0.039 13.3 4.2 1.3 8.3 0.0 2.5 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 DUF4288 PF14119.6 KFO98742.1 - 0.31 11.5 6.5 0.39 11.2 0.5 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) Pkinase_Tyr PF07714.17 KFO98743.1 - 4.1e-81 272.1 0.0 5.4e-81 271.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO98743.1 - 3.1e-27 95.6 0.0 4.8e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WIF PF02019.18 KFO98743.1 - 8.4e-17 61.1 1.1 1.1e-16 60.8 0.1 1.7 2 0 0 2 2 2 1 WIF domain SID-1_RNA_chan PF13965.6 KFO98743.1 - 0.044 12.2 0.3 0.066 11.6 0.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 LIM PF00412.22 KFO98744.1 - 7e-62 205.5 59.5 1.5e-14 54.0 3.2 5.1 5 0 0 5 5 5 5 LIM domain 7tm_1 PF00001.21 KFO98745.1 - 8.7e-50 169.5 16.6 8.7e-50 169.5 16.6 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFO98745.1 - 7.4e-07 28.8 17.1 9.1e-07 28.5 17.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 KFO98745.1 - 0.00017 21.0 14.8 0.00017 21.0 14.8 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 KFO98745.1 - 0.0021 17.7 9.6 0.0021 17.7 9.6 2.4 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFO98745.1 - 0.015 15.0 17.1 0.58 9.8 17.1 2.5 1 1 0 1 1 1 0 Olfactory receptor Srg PF02118.21 KFO98745.1 - 0.03 14.0 19.1 0.043 13.5 18.8 1.5 1 1 0 1 1 1 0 Srg family chemoreceptor DUF5409 PF17421.2 KFO98745.1 - 0.04 14.6 0.3 0.04 14.6 0.3 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5409) DUF373 PF04123.13 KFO98745.1 - 5.2 6.4 9.0 0.64 9.4 5.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF373) WD40 PF00400.32 KFO98746.1 - 5.7e-32 109.3 14.5 1.8e-06 28.5 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO98746.1 - 3.5e-11 43.3 1.8 0.57 10.5 0.0 5.5 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Collagen PF01391.18 KFO98746.1 - 6e-06 25.9 88.1 0.00011 21.8 30.6 9.9 6 1 3 9 9 9 3 Collagen triple helix repeat (20 copies) eIF2A PF08662.11 KFO98746.1 - 1.1e-05 25.5 3.4 0.042 13.7 0.7 2.9 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFO98746.1 - 0.00067 18.7 0.0 0.012 14.6 0.1 2.5 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein RNA_pol_Rpb4 PF03874.16 KFO98747.1 - 1.2e-26 93.5 5.9 1.4e-26 93.2 5.9 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Rop PF01815.16 KFO98747.1 - 0.0085 15.9 0.8 0.016 15.1 0.2 1.8 2 0 0 2 2 2 1 Rop protein AMMECR1 PF01871.17 KFO98748.1 - 1e-47 161.9 0.0 1.3e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 Glyco_transf_24 PF18404.1 KFO98750.1 - 5.8e-149 494.8 5.3 1.8e-148 493.2 4.2 2.3 2 0 0 2 2 2 1 Glucosyltransferase 24 Thioredoxin_15 PF18403.1 KFO98750.1 - 2.5e-70 236.7 1.1 2.1e-64 217.4 0.3 3.1 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_14 PF18402.1 KFO98750.1 - 2.1e-66 224.5 7.9 5.4e-62 210.0 0.6 3.9 4 0 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KFO98750.1 - 4.1e-55 186.6 1.3 2.8e-53 180.6 1.3 2.5 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KFO98750.1 - 2.9e-40 136.8 0.0 7.8e-40 135.4 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 KFO98750.1 - 2.9e-38 130.9 1.7 1.9e-37 128.2 0.2 2.8 3 0 0 3 3 3 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 KFO98750.1 - 7.5e-05 22.4 4.1 0.00016 21.3 0.4 3.0 3 0 0 3 3 3 1 Glycosyl transferase family 8 Lipase_GDSL_2 PF13472.6 KFO98751.1 - 0.051 14.0 0.0 0.13 12.6 0.0 1.8 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family PID_2 PF14719.6 KFO98752.1 - 1.8e-18 67.0 0.4 3e-18 66.3 0.4 1.3 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.23 KFO98752.1 - 9.1e-07 29.0 0.2 1.4e-06 28.4 0.2 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) HECT PF00632.25 KFO98753.1 - 5.1e-87 292.2 0.5 1.7e-86 290.5 0.0 2.1 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) WWE PF02825.20 KFO98753.1 - 0.00031 21.3 0.7 0.0012 19.3 0.7 2.0 1 1 0 1 1 1 1 WWE domain UNC45-central PF11701.8 KFO98753.1 - 0.0081 16.1 1.8 0.07 13.1 0.0 2.9 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.6 KFO98753.1 - 0.075 13.4 0.1 0.98 9.9 0.0 3.0 3 1 1 4 4 4 0 HEAT repeats MFS_1 PF07690.16 KFO98754.1 - 1.2e-53 182.3 44.4 3.2e-39 134.8 25.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily CbtA PF09490.10 KFO98754.1 - 0.7 9.6 7.7 0.33 10.7 3.6 2.5 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtA) zf-H2C2_2 PF13465.6 KFO98755.1 - 1e-24 85.8 76.6 5.7e-06 26.5 6.8 12.1 12 0 0 12 12 12 6 Zinc-finger double domain BTB PF00651.31 KFO98755.1 - 2e-21 76.3 0.1 4.7e-21 75.1 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 KFO98755.1 - 1.3e-19 69.5 79.7 2.6e-05 24.4 1.8 11.8 11 0 0 11 11 11 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO98755.1 - 3.2e-18 64.8 80.8 0.06 14.2 1.1 12.2 11 0 0 11 11 11 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO98755.1 - 1.1e-11 44.6 46.9 0.00016 21.9 0.1 9.8 10 0 0 10 10 10 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFO98755.1 - 1.2e-05 25.6 0.3 1.2e-05 25.6 0.3 8.5 9 0 0 9 9 9 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFO98755.1 - 2e-05 24.5 62.5 0.047 13.7 1.8 9.9 9 0 0 9 9 9 5 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 KFO98755.1 - 0.0055 16.6 5.4 0.0055 16.6 5.4 5.6 4 2 1 5 5 4 1 SprT-like zinc ribbon domain zf-C2H2_11 PF16622.5 KFO98755.1 - 0.017 14.9 0.2 0.017 14.9 0.2 6.2 7 0 0 7 7 6 0 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 KFO98755.1 - 0.017 15.4 0.7 0.017 15.4 0.7 5.5 3 2 2 5 5 5 0 C2H2-type zinc ribbon zf_UBZ PF18439.1 KFO98755.1 - 0.019 14.6 28.9 1 9.0 0.3 7.8 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 KFO98755.1 - 0.21 11.5 23.0 0.11 12.4 0.8 7.4 6 0 0 6 6 6 0 zinc-finger of a C2HC-type C2 PF00168.30 KFO98756.1 - 1e-31 109.3 3.6 2.9e-15 56.4 0.0 3.5 2 1 0 2 2 2 2 C2 domain RasGAP PF00616.19 KFO98756.1 - 1.3e-25 90.4 0.6 5.1e-16 59.0 0.0 3.2 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase PH PF00169.29 KFO98756.1 - 2e-16 60.4 0.7 2e-16 60.4 0.7 3.0 4 0 0 4 4 4 1 PH domain BTK PF00779.19 KFO98756.1 - 5.7e-13 48.4 2.1 1.2e-12 47.4 2.1 1.6 1 0 0 1 1 1 1 BTK motif CEP76-C2 PF15627.6 KFO98756.1 - 7.4e-05 22.4 0.3 0.3 10.6 0.0 2.8 3 0 0 3 3 3 2 CEP76 C2 domain PH_8 PF15409.6 KFO98756.1 - 0.0047 17.2 0.1 0.019 15.3 0.1 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain Glyco_trans_1_2 PF13524.6 KFO98756.1 - 0.033 14.6 0.0 0.079 13.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF104 PF01954.16 KFO98756.1 - 0.086 13.3 0.4 0.86 10.1 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function DUF104 DNA_pol3_beta_2 PF02767.16 KFO98756.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III beta subunit, central domain zf-rbx1 PF12678.7 KFO98757.1 - 3.8e-16 59.1 16.5 4.5e-16 58.9 16.5 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFO98757.1 - 1.6e-08 34.5 10.9 1.7e-08 34.4 10.9 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KFO98757.1 - 3e-08 33.9 13.1 4.2e-08 33.4 13.1 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFO98757.1 - 6.4e-05 22.7 12.1 0.00011 21.9 12.1 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFO98757.1 - 0.0011 18.8 10.2 0.0017 18.1 10.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFO98757.1 - 0.0017 18.2 13.6 0.0034 17.2 13.6 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 KFO98757.1 - 0.0076 16.2 9.6 0.05 13.5 5.2 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_5 PF14634.6 KFO98757.1 - 0.046 13.7 13.9 0.04 13.9 12.9 1.4 1 1 0 1 1 1 0 zinc-RING finger domain PHD PF00628.29 KFO98757.1 - 0.75 9.7 14.5 1.7 8.6 14.5 1.6 1 1 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.6 KFO98757.1 - 0.83 9.6 14.8 0.78 9.7 13.5 1.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KFO98757.1 - 1.6 8.6 13.2 0.59 10.0 11.0 1.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KFO98757.1 - 3 7.7 11.0 0.54 10.1 7.3 1.8 2 0 0 2 2 2 0 RING-like zinc finger zf-C3H2C3 PF17122.5 KFO98757.1 - 7 6.8 12.8 9.4 6.4 11.9 1.9 1 1 0 1 1 1 0 Zinc-finger Pkinase PF00069.25 KFO98758.1 - 8.6e-61 205.6 0.2 1.2e-60 205.1 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO98758.1 - 1.5e-33 116.2 0.1 3e-33 115.2 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 KFO98758.1 - 4.5e-15 55.9 2.5 4.5e-15 55.9 2.5 2.2 2 0 0 2 2 2 1 Regulator of G protein signaling domain Pkinase_fungal PF17667.1 KFO98758.1 - 7.9e-06 24.9 0.0 1.3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFO98758.1 - 0.00031 20.2 0.0 0.00045 19.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF4615 PF15393.6 KFO98758.1 - 0.069 13.7 1.5 0.077 13.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4615) Na_K-ATPase PF00287.18 KFO98759.1 - 3.8e-77 259.2 1.0 3.6e-76 256.0 1.0 1.9 1 1 0 1 1 1 1 Sodium / potassium ATPase beta chain CdiI_2 PF18593.1 KFO98759.1 - 0.12 13.0 0.0 0.2 12.3 0.0 1.3 1 0 0 1 1 1 0 CdiI immunity protein DP PF08781.10 KFO98760.1 - 4.1e-61 204.9 2.8 8.1e-61 203.9 2.8 1.5 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.20 KFO98760.1 - 1.3e-26 92.5 0.2 2.9e-26 91.3 0.2 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain FGGY_N PF00370.21 KFO98761.1 - 1.7e-38 132.6 0.0 5.4e-37 127.7 0.0 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KFO98761.1 - 1.2e-27 97.0 0.0 2.5e-27 95.9 0.0 1.5 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain XRN_M PF17846.1 KFO98762.1 - 2.4e-97 326.7 5.7 2.4e-97 326.7 5.7 2.2 2 0 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 KFO98762.1 - 1.2e-96 322.9 0.0 3.9e-96 321.2 0.0 2.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 KFO98762.1 - 6.1e-32 110.9 1.6 1.7e-31 109.5 1.6 1.7 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 KFO98762.1 - 4.8e-21 74.6 0.0 1.3e-20 73.3 0.0 1.8 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN1_D2_D3 PF18334.1 KFO98762.1 - 1.7e-07 31.3 0.0 1.7e-06 28.1 0.0 2.7 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain Dicer_dimer PF03368.14 KFO98762.1 - 0.076 13.2 0.0 0.42 10.8 0.0 2.3 1 0 0 1 1 1 0 Dicer dimerisation domain zf_Rg PF17915.1 KFO98762.1 - 0.23 10.9 0.5 0.66 9.4 0.0 2.0 2 0 0 2 2 2 0 Reverse gyrase zinc finger PI3_PI4_kinase PF00454.27 KFO98763.1 - 6.8e-59 199.7 0.1 1.5e-58 198.5 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KFO98763.1 - 4.1e-46 157.8 3.2 4.1e-46 157.8 3.2 2.6 3 0 0 3 3 3 1 FAT domain UME PF08064.13 KFO98763.1 - 2.5e-20 72.3 1.3 2.5e-19 69.1 0.1 3.3 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.20 KFO98763.1 - 1.9e-12 46.7 0.0 4.9e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 KFO98763.1 - 3.3e-07 30.0 2.2 1.6 9.2 0.0 7.6 9 0 0 9 9 9 2 HEAT repeat Mad3_BUB1_I PF08311.12 KFO98763.1 - 0.0037 17.3 1.7 0.028 14.4 0.1 3.3 3 0 0 3 3 3 1 Mad3/BUB1 homology region 1 Cnd1 PF12717.7 KFO98763.1 - 0.01 15.9 9.1 0.83 9.7 0.0 5.5 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KFO98763.1 - 0.011 16.2 0.3 17 6.0 0.0 4.8 5 0 0 5 5 5 0 HEAT-like repeat SgrT PF15894.5 KFO98763.1 - 0.016 15.2 2.2 0.38 10.8 0.1 2.7 2 0 0 2 2 2 0 Inhibitor of glucose uptake transporter SgrT Guanylate_kin PF00625.21 KFO98763.1 - 0.078 12.7 0.0 5.8 6.5 0.0 3.0 2 0 0 2 2 2 0 Guanylate kinase Arm PF00514.23 KFO98763.1 - 0.14 12.2 1.4 43 4.4 0.0 4.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat TPR_14 PF13428.6 KFO98763.1 - 0.32 11.9 2.0 99 4.2 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat V-ATPase_H_C PF11698.8 KFO98763.1 - 0.92 9.6 4.6 6.5 6.9 0.3 4.1 4 0 0 4 4 3 0 V-ATPase subunit H CH PF00307.31 KFO98764.1 - 2.3e-88 291.6 1.2 3.6e-25 88.3 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_1 PF00036.32 KFO98764.1 - 1.8e-09 36.4 1.5 6.4e-06 25.4 0.1 3.0 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFO98764.1 - 2e-07 31.4 0.0 8e-07 29.4 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair CAMSAP_CH PF11971.8 KFO98764.1 - 1.8e-06 27.7 0.0 0.00083 19.1 0.0 3.4 4 0 0 4 4 4 1 CAMSAP CH domain EF-hand_6 PF13405.6 KFO98764.1 - 4.3e-05 23.1 0.2 0.082 12.9 0.1 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KFO98764.1 - 0.0011 18.7 0.3 0.1 12.5 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KFO98764.1 - 0.0014 18.1 2.5 0.015 14.8 0.1 3.1 3 0 0 3 3 3 1 EF hand TRP_2 PF08344.11 KFO98765.1 - 2.2e-25 88.6 2.0 5.3e-25 87.4 2.0 1.7 1 0 0 1 1 1 1 Transient receptor ion channel II Ion_trans PF00520.31 KFO98765.1 - 2.1e-16 59.9 14.0 4e-16 59.0 14.0 1.4 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 KFO98765.1 - 2.9e-05 24.6 3.5 0.001 19.6 0.2 3.1 3 1 1 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFO98765.1 - 0.00011 22.6 0.1 1 10.1 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeats (many copies) DUF2407_C PF13373.6 KFO98765.1 - 0.047 13.9 0.1 0.26 11.4 0.0 2.3 3 0 0 3 3 3 0 DUF2407 C-terminal domain TALPID3 PF15324.6 KFO98765.1 - 0.45 8.1 2.6 0.22 9.2 0.3 1.5 2 0 0 2 2 2 0 Hedgehog signalling target CUB PF00431.20 KFO98766.1 - 2.7e-60 201.5 0.0 9.4e-30 103.2 0.0 2.2 2 0 0 2 2 2 2 CUB domain NTR PF01759.21 KFO98766.1 - 1.4e-15 57.0 0.6 3.7e-15 55.7 0.0 1.9 2 0 0 2 2 2 1 UNC-6/NTR/C345C module CUB_2 PF02408.20 KFO98766.1 - 1.9e-08 34.1 0.1 0.0019 18.0 0.0 2.6 2 0 0 2 2 2 2 CUB-like domain TIMP PF00965.17 KFO98766.1 - 0.0037 17.1 0.1 0.0085 15.9 0.1 1.6 1 1 0 1 1 1 1 Tissue inhibitor of metalloproteinase HlyIII PF03006.20 KFO98767.1 - 4.8e-24 85.3 8.0 7.5e-24 84.7 8.0 1.2 1 0 0 1 1 1 1 Haemolysin-III related Surp PF01805.20 KFO98768.1 - 4.8e-19 68.1 0.2 1.3e-18 66.7 0.2 1.8 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 KFO98768.1 - 2.5e-15 56.0 0.0 5.6e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) cwf21 PF08312.12 KFO98768.1 - 6.6e-10 39.0 2.7 6.6e-10 39.0 2.7 3.1 4 0 0 4 4 4 1 cwf21 domain CTK3 PF12243.8 KFO98768.1 - 3.7e-05 23.7 0.4 9.9e-05 22.3 0.1 1.8 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 CTD_bind PF04818.13 KFO98768.1 - 0.0009 20.0 0.6 0.0041 17.9 0.2 2.5 2 0 0 2 2 2 1 RNA polymerase II-binding domain. SET_assoc PF11767.8 KFO98768.1 - 0.015 15.0 0.1 0.034 13.8 0.1 1.6 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Sulfotransfer_1 PF00685.27 KFO98769.1 - 1.6e-13 50.8 0.0 1.9e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFO98769.1 - 1.8e-05 25.2 0.0 5.5e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Sulfotransferase family GDYXXLXY PF14345.6 KFO98769.1 - 0.13 12.1 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 GDYXXLXY protein Na_H_Exchanger PF00999.21 KFO98770.1 - 1.1e-83 281.2 34.2 2.6e-82 276.6 34.2 2.4 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Cpn60_TCP1 PF00118.24 KFO98771.1 - 1.4e-22 80.0 0.0 1.5e-22 79.9 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-C2H2 PF00096.26 KFO98772.1 - 5.4e-13 48.6 17.7 0.00011 22.5 3.7 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO98772.1 - 6.9e-13 48.4 8.8 2e-07 31.1 1.3 4.8 4 1 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFO98772.1 - 1e-05 26.0 27.4 0.0023 18.6 2.0 4.4 5 0 0 5 5 5 3 C2H2-type zinc finger DUF3446 PF11928.8 KFO98772.1 - 0.004 17.4 3.8 0.0047 17.2 0.1 2.8 2 0 0 2 2 2 1 Early growth response N-terminal domain zf-C2H2_6 PF13912.6 KFO98772.1 - 0.0096 15.9 7.4 0.96 9.5 0.5 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFO98772.1 - 0.017 15.0 9.6 2.6 8.1 0.7 3.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zf_RING PF16744.5 KFO98772.1 - 0.22 11.7 1.6 1.6 8.9 0.9 2.3 1 1 1 2 2 2 0 KIAA1045 RING finger zf-BED PF02892.15 KFO98772.1 - 0.3 11.2 7.1 1.9 8.6 7.1 2.4 1 1 0 1 1 1 0 BED zinc finger zf-C2H2_11 PF16622.5 KFO98772.1 - 0.91 9.3 8.7 15 5.5 0.3 3.7 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 KFO98772.1 - 2.3 8.7 8.3 4.9 7.7 0.5 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Reprolysin PF01421.19 KFO98777.1 - 2e-58 197.6 0.0 2e-58 197.6 0.0 1.9 2 0 0 2 2 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.12 KFO98777.1 - 4.9e-32 110.8 10.2 4.9e-32 110.8 10.2 3.5 3 1 0 3 3 1 1 ADAM cysteine-rich Pep_M12B_propep PF01562.19 KFO98777.1 - 1.2e-23 83.9 0.6 2e-23 83.1 0.6 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide Disintegrin PF00200.23 KFO98777.1 - 6.5e-20 71.7 29.4 6.5e-20 71.7 29.4 4.6 3 1 0 3 3 2 1 Disintegrin Reprolysin_5 PF13688.6 KFO98777.1 - 1.3e-18 67.9 0.1 1.3e-18 67.9 0.1 1.9 2 0 0 2 2 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFO98777.1 - 2.5e-11 44.2 0.0 6.3e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFO98777.1 - 1.1e-08 35.2 2.6 1.5e-07 31.5 2.6 2.3 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFO98777.1 - 1.8e-06 27.7 1.8 9.2e-06 25.4 1.8 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.13 KFO98777.1 - 0.0012 19.1 12.4 0.0012 19.1 12.4 5.4 4 1 1 5 5 1 1 EGF-like domain Peptidase_M43 PF05572.13 KFO98777.1 - 0.012 15.5 0.5 3.2 7.6 0.1 3.0 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A Peptidase_M54 PF07998.11 KFO98777.1 - 0.042 13.8 0.3 0.11 12.4 0.3 1.7 1 0 0 1 1 1 0 Peptidase family M54 Peptidase_M10 PF00413.24 KFO98777.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.9 KFO98777.1 - 0.18 10.7 0.2 0.34 9.8 0.2 1.4 1 0 0 1 1 1 0 Peptidase M66 GDNF PF02351.16 KFO98779.1 - 7.3e-44 148.6 43.3 6.7e-23 81.5 7.4 3.1 3 0 0 3 3 3 3 GDNF/GAS1 domain Kelch_1 PF01344.25 KFO98780.1 - 2e-26 91.3 1.9 4.4e-05 23.0 0.0 6.8 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 KFO98780.1 - 2.3e-22 78.5 6.1 2.1e-07 31.0 0.0 6.2 5 0 0 5 5 5 5 Kelch motif Kelch_5 PF13854.6 KFO98780.1 - 3.5e-21 74.7 15.5 4.7e-06 26.5 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Lectin_C PF00059.21 KFO98780.1 - 1.4e-19 70.8 0.5 1.4e-19 70.8 0.5 3.5 4 0 0 4 4 3 1 Lectin C-type domain PSI PF01437.25 KFO98780.1 - 8e-19 67.9 107.8 1.2e-12 48.1 10.1 7.7 7 1 0 7 7 5 5 Plexin repeat Kelch_3 PF13415.6 KFO98780.1 - 4.4e-17 61.9 3.7 0.0085 16.4 0.0 7.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 KFO98780.1 - 1.7e-14 53.5 4.4 1.8e-05 24.6 0.0 6.3 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.15 KFO98780.1 - 1.7e-13 49.9 3.0 0.037 14.0 0.0 6.4 6 0 0 6 6 6 4 Kelch motif CUB PF00431.20 KFO98780.1 - 6.9e-13 48.9 0.0 2.9e-12 46.9 0.0 2.1 2 0 0 2 2 1 1 CUB domain Laminin_EGF PF00053.24 KFO98780.1 - 0.0018 18.4 16.6 0.0018 18.4 16.6 7.7 8 2 1 9 9 3 2 Laminin EGF domain PSI_integrin PF17205.3 KFO98780.1 - 0.0088 15.8 8.5 0.0088 15.8 8.5 7.3 6 0 0 6 6 5 2 Integrin plexin domain TMEM100 PF16311.5 KFO98780.1 - 0.018 14.6 0.3 0.045 13.3 0.3 1.6 1 0 0 1 1 1 0 Transmembrane protein 100 Cyclotide PF03784.13 KFO98781.1 - 0.4 10.8 1.6 1.1 9.5 1.6 1.7 1 0 0 1 1 1 0 Cyclotide family HCO3_cotransp PF00955.21 KFO98782.1 - 2e-158 528.4 9.8 2.7e-158 528.0 9.8 1.2 1 0 0 1 1 1 1 HCO3- transporter family PTS_EIIA_2 PF00359.22 KFO98782.1 - 1.1e-05 25.4 0.1 0.00031 20.6 0.1 2.8 2 1 0 2 2 2 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Band_3_cyto PF07565.13 KFO98782.1 - 3e-05 24.0 0.0 6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Band 3 cytoplasmic domain 7tm_1 PF00001.21 KFO98783.1 - 2.1e-76 256.7 11.0 2.7e-76 256.4 11.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFO98783.1 - 7.1e-09 35.4 10.8 1.4e-08 34.4 10.8 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFO98783.1 - 4.2e-05 23.3 8.7 4.2e-05 23.3 8.7 2.0 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFO98783.1 - 6.7e-05 22.8 4.9 6.7e-05 22.8 4.9 1.9 2 1 1 3 3 3 1 Olfactory receptor S8_pro-domain PF16470.5 KFO98783.1 - 0.062 14.1 0.4 0.11 13.3 0.4 1.3 1 0 0 1 1 1 0 Peptidase S8 pro-domain DUF2401 PF10287.9 KFO98783.1 - 0.07 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) Haemadin PF09065.10 KFO98783.1 - 0.2 11.5 0.4 0.51 10.2 0.2 1.8 2 0 0 2 2 2 0 Haemadin Insulin_TMD PF17870.1 KFO98783.1 - 2.8 8.1 6.4 0.47 10.6 1.8 2.2 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DDRGK PF09756.9 KFO98784.1 - 1.4e-68 230.3 30.9 1.4e-68 230.3 30.9 1.4 2 0 0 2 2 2 1 DDRGK domain PCI PF01399.27 KFO98784.1 - 0.00019 21.9 0.1 0.00039 20.9 0.1 1.5 1 0 0 1 1 1 1 PCI domain FeoC PF09012.10 KFO98784.1 - 0.00036 20.5 0.1 0.61 10.2 0.0 2.6 2 0 0 2 2 2 2 FeoC like transcriptional regulator HTH_DeoR PF08220.12 KFO98784.1 - 0.0079 15.9 0.2 1.6 8.6 0.0 2.4 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain DUF3347 PF11827.8 KFO98784.1 - 0.036 14.3 7.5 0.068 13.3 7.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Zip PF02535.22 KFO98784.1 - 0.25 10.5 2.8 0.27 10.4 2.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PPL5 PF18168.1 KFO98784.1 - 2.2 7.5 9.2 3.3 6.9 9.2 1.3 1 0 0 1 1 1 0 Prim-pol family 5 Presenilin PF01080.17 KFO98784.1 - 2.4 6.8 13.6 2.8 6.6 13.6 1.2 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 KFO98784.1 - 3.6 6.3 10.7 4.5 6.0 10.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Ribosomal_S25 PF03297.15 KFO98784.1 - 3.8 7.8 16.0 0.11 12.6 2.8 2.9 1 1 1 2 2 2 0 S25 ribosomal protein Spem1 PF15670.5 KFO98784.1 - 3.9 7.0 8.2 1.2 8.6 3.9 1.9 1 1 1 2 2 2 0 Spermatid maturation protein 1 Hid1 PF12722.7 KFO98784.1 - 4.3 5.3 10.6 4.7 5.2 10.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PA26 PF04636.13 KFO98784.1 - 5.9 5.7 11.5 7.6 5.3 11.5 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) eIF-3_zeta PF05091.12 KFO98784.1 - 8.4 5.2 16.0 12 4.8 16.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Vfa1 PF08432.10 KFO98784.1 - 8.7 6.6 21.5 14 6.0 21.5 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Trypan_PARP PF05887.11 KFO98785.1 - 0.45 10.5 119.3 15 5.5 31.0 4.0 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) Fez1 PF06818.15 KFO98786.1 - 7.4e-77 258.3 47.0 3.6e-74 249.5 24.0 2.3 2 0 0 2 2 2 2 Fez1 ATG16 PF08614.11 KFO98786.1 - 0.00033 20.9 7.6 0.00033 20.9 7.6 4.0 3 2 1 4 4 4 1 Autophagy protein 16 (ATG16) PKcGMP_CC PF16808.5 KFO98786.1 - 0.0018 18.1 2.2 0.0018 18.1 2.2 5.6 4 1 1 5 5 5 1 Coiled-coil N-terminus of cGMP-dependent protein kinase CALCOCO1 PF07888.11 KFO98786.1 - 0.22 10.4 48.6 0.0095 14.9 29.0 2.2 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like PyocinActivator PF11112.8 KFO98786.1 - 0.28 11.4 1.8 4.7 7.4 0.4 2.6 2 0 0 2 2 2 0 Pyocin activator protein PrtN FAM184 PF15665.5 KFO98786.1 - 1.4 8.6 52.4 0.23 11.2 20.2 3.3 3 0 0 3 3 3 0 Family with sequence similarity 184, A and B ERM PF00769.19 KFO98786.1 - 1.6 8.5 59.7 0.041 13.7 24.6 3.3 2 1 1 3 3 3 0 Ezrin/radixin/moesin family U-box PF04564.15 KFO98787.1 - 3.1e-26 91.4 0.1 6.5e-26 90.3 0.1 1.6 1 0 0 1 1 1 1 U-box domain zf-RING_5 PF14634.6 KFO98787.1 - 3.3e-05 23.8 5.5 3.3e-05 23.8 5.5 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFO98787.1 - 0.00012 22.0 4.9 0.00012 22.0 4.9 3.6 4 0 0 4 4 4 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFO98787.1 - 0.00089 19.1 6.5 0.0012 18.6 5.0 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFO98787.1 - 0.0072 16.2 4.4 0.0072 16.2 4.4 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFO98787.1 - 0.013 15.4 5.6 0.05 13.5 5.6 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFO98787.1 - 0.054 13.7 10.5 0.033 14.4 7.2 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF3496 PF12001.8 KFO98787.1 - 0.11 12.9 0.1 0.26 11.6 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3496) FYVE PF01363.21 KFO98787.1 - 0.22 11.7 5.1 0.78 9.9 5.1 2.0 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_2 PF13639.6 KFO98787.1 - 0.9 9.9 14.2 0.064 13.6 5.8 3.0 3 0 0 3 3 3 0 Ring finger domain zf-RING_10 PF16685.5 KFO98787.1 - 0.94 9.7 6.8 0.85 9.8 3.8 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 Hormone_5 PF00184.17 KFO98788.1 - 7e-32 110.1 25.1 7.7e-32 110.0 25.1 1.0 1 0 0 1 1 1 1 Neurohypophysial hormones, C-terminal Domain MRP-S26 PF14943.6 KFO98789.1 - 2.1e-32 112.4 15.3 2.3e-32 112.2 15.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 Spem1 PF15670.5 KFO98789.1 - 0.51 9.9 3.5 0.53 9.8 3.5 1.0 1 0 0 1 1 1 0 Spermatid maturation protein 1 DUF5401 PF17380.2 KFO98789.1 - 2.1 6.3 17.5 2.3 6.2 17.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) I-set PF07679.16 KFO98790.1 - 1.4e-35 121.2 0.8 7.4e-14 51.6 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO98790.1 - 3.5e-35 120.5 1.2 2.3e-14 53.7 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFO98790.1 - 2.5e-29 101.3 0.9 1.6e-14 53.8 0.0 4.1 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFO98790.1 - 1.3e-28 99.1 1.1 3.2e-13 49.8 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFO98790.1 - 7.3e-15 55.1 3.8 0.00011 22.4 0.1 5.2 3 2 1 4 4 4 4 Immunoglobulin V-set domain Ig_5 PF16681.5 KFO98790.1 - 5.3e-10 39.6 0.1 0.008 16.6 0.0 3.6 3 1 0 3 3 3 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFO98790.1 - 4.6e-07 29.8 0.0 0.01 15.8 0.0 3.4 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFO98790.1 - 6.2e-06 25.7 0.0 0.71 9.5 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain Ig_4 PF16680.5 KFO98790.1 - 1.8e-05 24.9 0.1 0.27 11.5 0.0 3.7 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFO98790.1 - 4.8e-05 23.3 0.1 0.082 13.0 0.0 2.7 3 0 0 3 3 2 2 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.11 KFO98790.1 - 0.0031 17.5 0.1 1.3 9.0 0.0 3.0 3 0 0 3 3 3 1 CD47 immunoglobulin-like domain Ig_C17orf99 PF17736.1 KFO98790.1 - 0.024 14.7 0.1 0.64 10.1 0.0 2.9 2 1 0 2 2 2 0 C17orf99 Ig domain C2-set PF05790.15 KFO98790.1 - 0.063 13.5 0.2 88 3.4 0.0 4.1 4 1 0 4 4 4 0 Immunoglobulin C2-set domain I-set PF07679.16 KFO98791.1 - 9.9e-37 124.9 2.8 3.8e-15 55.7 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO98791.1 - 2e-36 124.4 2.7 5.7e-15 55.7 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFO98791.1 - 2.9e-27 94.7 4.8 1.6e-13 50.7 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFO98791.1 - 6.2e-27 93.8 2.5 1.2e-10 41.6 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFO98791.1 - 3.3e-13 49.8 7.6 0.00043 20.4 0.2 5.1 3 2 1 4 4 4 3 Immunoglobulin V-set domain Izumo-Ig PF16706.5 KFO98791.1 - 8e-08 32.2 0.1 0.014 15.4 0.0 3.5 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFO98791.1 - 1e-07 32.3 0.0 0.24 11.8 0.0 3.4 3 1 0 3 3 3 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFO98791.1 - 0.00021 20.8 0.1 1.2 8.8 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain Ig_4 PF16680.5 KFO98791.1 - 0.00027 21.2 0.1 0.65 10.3 0.0 3.7 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain V-set_CD47 PF08204.11 KFO98791.1 - 0.0013 18.7 2.1 0.39 10.7 0.1 3.1 3 1 0 3 3 3 2 CD47 immunoglobulin-like domain C2-set_2 PF08205.12 KFO98791.1 - 0.02 14.9 0.2 0.96 9.6 0.0 2.6 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 KFO98792.1 - 6e-62 206.2 0.0 3.1e-16 59.7 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 KFO98792.1 - 3.2e-54 180.9 0.0 1.6e-15 56.9 0.0 5.6 6 0 0 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.6 KFO98792.1 - 1.1e-38 131.4 0.0 8.6e-10 38.8 0.0 5.3 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 KFO98792.1 - 1.1e-34 118.4 0.0 1.4e-11 44.4 0.0 6.2 5 1 0 5 5 5 5 Immunoglobulin domain V-set PF07686.17 KFO98792.1 - 2e-26 92.3 0.0 8.2e-08 32.4 0.0 7.0 5 2 1 6 6 6 5 Immunoglobulin V-set domain fn3 PF00041.21 KFO98792.1 - 4.1e-14 52.7 0.0 1.6e-05 25.1 0.0 3.0 3 0 0 3 3 2 2 Fibronectin type III domain Ig_6 PF18452.1 KFO98792.1 - 1.1e-09 37.7 0.0 0.33 10.6 0.0 5.3 5 0 0 5 5 5 2 Immunoglobulin domain Ig_4 PF16680.5 KFO98792.1 - 1.8e-08 34.5 0.0 0.016 15.5 0.0 5.1 5 0 0 5 5 5 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFO98792.1 - 1.8e-06 27.9 0.0 4.2 7.5 0.0 4.4 4 0 0 4 4 4 3 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 KFO98792.1 - 2.7e-05 24.2 0.5 0.054 13.6 0.0 4.5 5 0 0 5 5 5 1 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFO98792.1 - 4.6e-05 23.7 0.0 0.6 10.5 0.0 5.0 5 0 0 5 5 5 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Pur_ac_phosph_N PF16656.5 KFO98792.1 - 0.0037 17.8 0.7 0.26 11.9 1.0 3.2 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Tissue_fac PF01108.17 KFO98792.1 - 0.042 13.7 0.1 0.24 11.3 0.1 2.3 2 0 0 2 2 2 0 Tissue factor Ldr_toxin PF13940.6 KFO98792.1 - 0.054 13.6 2.9 4.7 7.4 0.3 3.2 2 1 1 3 3 2 0 Toxin Ldr, type I toxin-antitoxin system DUF2369 PF10179.9 KFO98792.1 - 0.1 13.0 0.0 2.3 8.6 0.0 3.0 4 0 0 4 4 4 0 Uncharacterised conserved protein (DUF2369) V-set_CD47 PF08204.11 KFO98792.1 - 0.15 12.1 0.0 35 4.4 0.0 3.7 4 0 0 4 4 4 0 CD47 immunoglobulin-like domain Ig_3 PF13927.6 KFO98793.1 - 7.5e-24 84.1 4.2 1.5e-13 51.1 1.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFO98793.1 - 2.4e-20 72.4 0.1 1.8e-10 40.7 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFO98793.1 - 1.7e-14 53.9 3.4 8.9e-10 38.8 1.1 2.7 1 1 1 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFO98793.1 - 9e-14 51.6 1.1 4.6e-08 33.2 0.0 3.2 2 1 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.25 KFO98793.1 - 1e-12 48.1 1.3 2.1e-05 24.6 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFO98793.1 - 1.8e-05 24.7 0.1 0.0044 17.1 0.0 2.8 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 KFO98793.1 - 3.3e-05 23.9 0.5 0.0062 16.6 0.1 2.3 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFO98793.1 - 0.00094 19.5 0.7 0.56 10.6 0.1 2.5 2 1 0 2 2 2 2 Immunoglobulin C1-set domain Adeno_E3_CR2 PF02439.15 KFO98793.1 - 0.062 13.1 3.4 0.12 12.2 3.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Protocadherin PF08374.11 KFO98793.1 - 0.065 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Protocadherin Cnd1 PF12717.7 KFO98794.1 - 6.2e-36 123.9 22.3 3e-28 98.9 0.4 8.0 7 1 1 8 8 8 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFO98794.1 - 4.8e-12 45.0 6.7 0.59 10.5 0.1 8.1 7 0 0 7 7 7 4 HEAT repeat Adaptin_N PF01602.20 KFO98794.1 - 1.6e-08 33.6 15.5 0.00033 19.4 0.8 4.6 5 0 0 5 5 5 2 Adaptin N terminal region RTP1_C1 PF10363.9 KFO98794.1 - 7.9e-05 22.8 1.0 3.3 7.9 0.1 6.1 7 0 0 7 7 7 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 KFO98794.1 - 0.00036 19.8 8.8 0.012 14.8 0.1 4.4 4 0 0 4 4 4 2 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KFO98794.1 - 0.00069 20.0 4.3 2.6 8.5 0.1 5.4 6 1 2 8 8 8 1 HEAT repeats DUF3013 PF11217.8 KFO98794.1 - 0.00078 19.4 0.8 0.0016 18.3 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3013) Cohesin_HEAT PF12765.7 KFO98794.1 - 0.011 16.0 0.3 2.9 8.3 0.1 3.6 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion UNC45-central PF11701.8 KFO98794.1 - 0.093 12.7 4.2 1.3 9.0 0.2 4.5 4 1 0 4 4 4 0 Myosin-binding striated muscle assembly central OSCP PF00213.18 KFO98794.1 - 0.097 12.8 2.3 0.39 10.8 1.6 2.4 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit Vps26 PF03643.15 KFO98795.1 - 1.7e-130 434.0 6.5 2e-130 433.8 6.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KFO98795.1 - 0.00013 22.1 0.5 0.1 12.7 0.0 3.1 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KFO98795.1 - 0.0019 18.7 0.1 0.11 13.0 0.0 2.8 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain EVE PF01878.18 KFO98796.1 - 4.2e-50 169.5 0.1 7.5e-50 168.7 0.1 1.4 1 0 0 1 1 1 1 EVE domain Acyl-CoA_dh_1 PF00441.24 KFO98797.1 - 6.7e-46 156.2 4.9 8.6e-46 155.9 4.3 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFO98797.1 - 3.6e-29 101.7 0.4 6.8e-29 100.8 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFO98797.1 - 1.6e-26 92.3 0.0 3.3e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFO98797.1 - 5.9e-21 75.2 2.3 9.2e-21 74.5 2.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AcylCoA_dehyd_C PF12186.8 KFO98797.1 - 0.063 13.4 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal Glyco_transf_43 PF03360.16 KFO98798.1 - 2.6e-75 252.8 0.0 3e-75 252.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 MRP-S32 PF10210.9 KFO98799.1 - 4.6e-37 126.4 1.8 5.8e-37 126.1 1.8 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S32 SH2 PF00017.24 KFO98800.1 - 1.2e-13 50.9 0.1 1.8e-13 50.4 0.1 1.3 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.16 KFO98800.1 - 2e-12 47.2 1.0 3.1e-12 46.6 0.3 1.6 2 0 0 2 2 2 1 SOCS box SH2_2 PF14633.6 KFO98800.1 - 0.001 18.5 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 SH2 domain Condensation PF00668.20 KFO98800.1 - 0.022 13.4 0.0 0.029 13.0 0.0 1.1 1 0 0 1 1 1 0 Condensation domain CARD PF00619.21 KFO98801.1 - 6.2e-16 58.2 0.1 1e-15 57.5 0.1 1.4 1 0 0 1 1 1 1 Caspase recruitment domain Death PF00531.22 KFO98801.1 - 1.6e-13 50.6 0.1 2.7e-12 46.7 0.1 2.2 2 0 0 2 2 2 1 Death domain CARD_2 PF16739.5 KFO98801.1 - 0.00075 19.4 0.1 0.0016 18.4 0.1 1.5 1 0 0 1 1 1 1 Caspase recruitment domain ABC_tran_CTD PF16326.5 KFO98803.1 - 0.00043 20.5 7.1 0.00043 20.5 7.1 11.5 2 1 9 12 12 12 4 ABC transporter C-terminal domain Shugoshin_N PF07558.11 KFO98803.1 - 0.065 13.1 0.2 0.065 13.1 0.2 5.7 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region Tmemb_cc2 PF10267.9 KFO98804.1 - 7e-161 535.8 13.2 8e-161 535.7 13.2 1.0 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Rootletin PF15035.6 KFO98804.1 - 0.0033 17.5 0.2 0.0033 17.5 0.2 3.3 2 1 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion DUF2407_C PF13373.6 KFO98804.1 - 0.021 15.0 0.2 0.021 15.0 0.2 2.1 2 0 0 2 2 2 0 DUF2407 C-terminal domain DUF2417 PF10329.9 KFO98804.1 - 0.038 13.4 0.2 0.076 12.4 0.2 1.4 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Exonuc_VII_L PF02601.15 KFO98804.1 - 0.13 11.8 18.2 1 8.8 9.0 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit VPS11_C PF12451.8 KFO98804.1 - 0.14 12.4 0.5 0.14 12.4 0.5 3.8 6 0 0 6 6 3 0 Vacuolar protein sorting protein 11 C terminal Fib_alpha PF08702.10 KFO98804.1 - 0.19 11.9 26.7 0.041 14.1 6.8 3.0 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF4735 PF15882.5 KFO98804.1 - 0.55 9.6 12.0 0.23 10.9 1.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4735) Cytochrom_C_2 PF01322.20 KFO98804.1 - 0.66 10.9 8.1 0.59 11.0 1.5 2.7 2 1 0 2 2 2 0 Cytochrome C' DDHD PF02862.17 KFO98804.1 - 0.76 9.9 6.4 8.9 6.4 0.1 2.2 2 0 0 2 2 2 0 DDHD domain CorA PF01544.18 KFO98804.1 - 1.2 8.4 12.7 2.9 7.1 0.5 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF4483 PF14825.6 KFO98804.1 - 2.4 7.9 10.6 0.022 14.5 1.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4483) G10 PF01125.17 KFO98804.1 - 3.4 7.4 11.4 0.11 12.3 2.9 2.4 2 1 0 2 2 2 0 G10 protein Lipoprotein_20 PF13942.6 KFO98804.1 - 3.9 7.3 18.3 0.77 9.7 4.8 2.4 2 1 0 2 2 2 0 YfhG lipoprotein COG2 PF06148.11 KFO98804.1 - 4.8 7.3 18.6 0.54 10.4 5.9 3.3 2 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2894 PF11445.8 KFO98804.1 - 5.7 7.4 11.3 6 7.3 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) NDUFA12 PF05071.16 KFO98805.1 - 2.9e-30 105.0 4.2 3.4e-30 104.7 4.2 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Hormone_recep PF00104.30 KFO98806.1 - 4.6e-44 150.5 1.0 8.7e-44 149.6 0.2 1.8 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFO98806.1 - 1.9e-31 108.3 15.6 4.5e-31 107.1 15.6 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF2318 PF10080.9 KFO98806.1 - 5.4 7.2 11.0 0.058 13.5 1.2 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) RhoGEF PF00621.20 KFO98807.1 - 5.9e-37 127.7 2.4 2e-36 125.9 2.4 2.0 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 KFO98807.1 - 7.7e-20 70.8 10.2 7.7e-20 70.8 10.2 2.1 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.29 KFO98807.1 - 8.9e-18 64.7 2.0 2e-08 34.7 0.0 3.1 3 0 0 3 3 3 2 PH domain IQ_SEC7_PH PF16453.5 KFO98807.1 - 3.4e-05 23.9 0.9 8.7e-05 22.5 0.1 2.0 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 KFO98807.1 - 0.00019 21.2 7.6 0.00074 19.4 2.3 3.1 3 1 0 3 3 3 1 Pleckstrin homology domain FYVE_2 PF02318.16 KFO98807.1 - 0.00051 20.2 8.2 0.0022 18.2 8.2 2.1 1 0 0 1 1 1 1 FYVE-type zinc finger PH_11 PF15413.6 KFO98807.1 - 0.0016 18.8 3.0 0.12 12.8 0.1 3.7 4 0 0 4 4 4 1 Pleckstrin homology domain Vezatin PF12632.7 KFO98808.1 - 6.1e-90 301.4 0.2 6.1e-90 301.4 0.2 2.3 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes ATPase_2 PF01637.18 KFO98808.1 - 0.41 10.5 2.5 0.26 11.2 0.1 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF641 PF04859.12 KFO98808.1 - 5.6 7.3 10.2 0.13 12.6 0.4 2.8 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) Peptidase_M24 PF00557.24 KFO98810.1 - 4.6e-47 160.4 0.0 5.9e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 UCH PF00443.29 KFO98811.1 - 2.9e-55 187.6 0.0 6.9e-55 186.3 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFO98811.1 - 2.6e-20 72.5 8.0 2.6e-20 72.5 8.0 3.1 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KFO98811.1 - 2.4e-15 57.0 3.6 4.9e-15 55.9 3.6 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MPM1 PF17234.2 KFO98811.1 - 0.055 13.7 2.9 0.12 12.7 2.9 1.4 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 zf-UBP_var PF17807.1 KFO98811.1 - 0.94 9.3 5.3 0.16 11.7 0.8 2.0 2 0 0 2 2 2 0 Variant UBP zinc finger Laminin_N PF00055.17 KFO98813.1 - 1.2e-42 146.2 0.0 1.2e-42 146.2 0.0 2.5 2 1 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 KFO98813.1 - 5.7e-31 106.4 53.2 6.9e-12 45.3 5.9 5.4 4 1 1 5 5 5 4 Laminin EGF domain NTR PF01759.21 KFO98813.1 - 2.4e-23 82.0 0.3 4.7e-23 81.0 0.3 1.5 1 0 0 1 1 1 1 UNC-6/NTR/C345C module F5_F8_type_C PF00754.25 KFO98813.1 - 0.002 18.3 0.0 0.0043 17.2 0.0 1.6 1 0 0 1 1 1 1 F5/8 type C domain LSM PF01423.22 KFO98814.1 - 4.4e-17 61.5 0.0 4.9e-17 61.4 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFO98814.1 - 0.032 14.4 0.0 0.036 14.2 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain Amidohydro_3 PF07969.11 KFO98815.1 - 1.7e-21 77.3 0.8 1.1e-13 51.6 0.0 2.5 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KFO98815.1 - 1.1e-19 71.0 2.3 1.9e-18 66.9 2.3 2.2 1 1 0 1 1 1 1 Amidohydrolase family Lyase_aromatic PF00221.19 KFO98816.1 - 5e-195 648.6 0.0 5.9e-195 648.3 0.0 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Par3_HAL_N_term PF12053.8 KFO98816.1 - 2.9e-05 24.2 0.0 8.2e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins Peptidase_M1 PF01433.20 KFO98817.1 - 6.3e-46 156.7 0.0 1.1e-45 155.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KFO98817.1 - 2.4e-36 124.3 0.2 4.5e-36 123.4 0.2 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KFO98817.1 - 2.1e-19 70.4 0.0 3e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M48 PF01435.18 KFO98817.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M48 FH2 PF02181.23 KFO98818.1 - 1.2e-78 264.9 14.2 1.9e-78 264.2 14.2 1.3 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 KFO98818.1 - 3.8e-31 108.2 4.1 3.8e-31 108.2 4.1 2.2 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 KFO98818.1 - 6.3e-17 61.7 0.3 6.3e-17 61.7 0.3 2.2 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH1 PF06346.12 KFO98818.1 - 2.3e-08 33.9 67.9 2.3e-08 33.9 67.9 2.5 1 1 1 2 2 2 2 Formin Homology Region 1 WH2 PF02205.20 KFO98818.1 - 0.00037 20.2 0.2 0.001 18.8 0.2 1.8 1 0 0 1 1 1 1 WH2 motif CDT1 PF08839.11 KFO98818.1 - 0.018 15.3 1.9 0.057 13.7 1.9 1.8 1 1 0 1 1 1 0 DNA replication factor CDT1 like Adenylsucc_synt PF00709.21 KFO98819.1 - 2.9e-163 543.7 0.0 3.3e-163 543.5 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase hSac2 PF12456.8 KFO98819.1 - 0.086 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Inositol phosphatase DUF5442 PF17514.2 KFO98819.1 - 0.097 12.9 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5442) Siva PF05458.12 KFO98820.1 - 9.8e-20 70.9 23.7 1e-19 70.9 23.7 1.0 1 0 0 1 1 1 1 Cd27 binding protein (Siva) Pkinase PF00069.25 KFO98821.1 - 1.5e-78 263.8 0.0 2e-78 263.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO98821.1 - 8.9e-36 123.5 0.0 1.3e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KFO98821.1 - 8.6e-12 45.5 0.1 2.2e-11 44.2 0.1 1.7 1 0 0 1 1 1 1 PH domain Pkinase_C PF00433.24 KFO98821.1 - 1.3e-10 41.8 3.3 3.4e-10 40.4 3.3 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFO98821.1 - 9.5e-09 35.0 0.0 8.1e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 KFO98821.1 - 0.044 12.8 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PH_11 PF15413.6 KFO98821.1 - 0.054 13.9 0.1 0.32 11.5 0.0 2.3 3 0 0 3 3 3 0 Pleckstrin homology domain APH PF01636.23 KFO98821.1 - 0.16 11.9 0.0 0.45 10.4 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family BTB PF00651.31 KFO98822.1 - 2.6e-26 92.0 0.6 4.3e-26 91.3 0.6 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.6 KFO98822.1 - 1.5e-13 50.3 31.0 0.00022 21.8 2.9 5.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KFO98822.1 - 4.6e-13 48.9 31.4 0.00054 20.3 1.5 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO98822.1 - 4.4e-12 45.9 25.8 2.6e-07 30.8 1.3 5.6 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFO98822.1 - 7.4e-05 22.9 0.6 0.016 15.5 0.0 4.5 6 0 0 6 6 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFO98822.1 - 0.0005 20.4 13.4 0.11 12.9 0.1 4.9 5 0 0 5 5 5 2 Zinc-finger of C2H2 type Zn-C2H2_12 PF18112.1 KFO98822.1 - 0.0056 17.1 1.7 0.0056 17.1 1.7 3.3 3 0 0 3 3 3 1 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_6 PF13912.6 KFO98822.1 - 0.049 13.6 22.6 0.72 9.9 0.2 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFO98822.1 - 0.063 13.0 0.6 0.063 13.0 0.6 4.2 4 0 0 4 4 4 0 zinc-finger C2H2-type GAGA PF09237.11 KFO98822.1 - 0.091 12.6 6.6 0.53 10.1 0.2 3.3 2 1 1 3 3 3 0 GAGA factor zf-LYAR PF08790.11 KFO98822.1 - 0.91 9.5 9.5 5 7.1 0.2 3.8 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf_ZIC PF18366.1 KFO98822.1 - 2.9 8.1 14.4 7.4 6.8 0.6 4.8 3 1 2 5 5 5 0 Zic proteins zinc finger domain FYVE PF01363.21 KFO98822.1 - 3.3 7.9 17.0 1.6 8.9 2.8 3.9 2 1 2 4 4 4 0 FYVE zinc finger PLDc_3 PF13918.6 KFO98823.1 - 5.7e-40 136.8 0.0 9.7e-40 136.1 0.0 1.3 1 0 0 1 1 1 1 PLD-like domain PLDc_2 PF13091.6 KFO98823.1 - 3.7e-24 85.1 0.5 1.5e-11 44.3 0.1 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KFO98823.1 - 2.5e-13 49.6 4.9 1.7e-08 34.3 0.7 2.4 2 0 0 2 2 2 2 Phospholipase D Active site motif DOR PF14839.6 KFO98824.1 - 6.7e-32 111.4 25.0 1.4e-30 107.1 19.5 2.9 1 1 1 2 2 2 2 DOR family G_glu_transpept PF01019.21 KFO98825.1 - 4.2e-130 434.9 0.0 5e-130 434.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Rab5ip PF07019.12 KFO98826.1 - 1e-18 67.7 10.3 1.1e-18 67.5 10.3 1.0 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Yip1 PF04893.17 KFO98826.1 - 0.024 14.4 1.5 0.024 14.4 1.5 1.9 1 1 1 2 2 2 0 Yip1 domain DUF2244 PF10003.9 KFO98826.1 - 0.032 13.9 0.8 0.032 13.9 0.8 1.9 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Clc-like PF07062.12 KFO98826.1 - 0.084 12.3 3.5 0.1 12.1 3.5 1.0 1 0 0 1 1 1 0 Clc-like EF-hand_1 PF00036.32 KFO98827.1 - 4.8e-16 57.0 9.1 1.3e-07 30.7 1.6 4.4 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 KFO98827.1 - 1.1e-13 51.4 6.1 6.6e-07 29.7 0.2 2.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KFO98827.1 - 2.5e-12 45.7 9.1 7.6e-08 31.7 0.9 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 KFO98827.1 - 2.4e-07 30.5 7.4 0.0083 15.9 0.1 3.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KFO98827.1 - 3.3e-06 26.3 2.9 1.8e-05 24.0 1.5 2.6 2 0 0 2 2 2 1 EF hand EF-hand_11 PF08976.11 KFO98827.1 - 0.00013 22.8 0.1 0.00084 20.2 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain GPHH PF16905.5 KFO98827.1 - 0.0016 18.2 0.0 0.23 11.2 0.0 2.3 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_9 PF14658.6 KFO98827.1 - 0.0018 18.6 0.0 2.1 8.8 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.13 KFO98827.1 - 0.002 18.1 0.0 3.6 7.7 0.0 2.9 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) Syntaxin PF00804.25 KFO98827.1 - 0.011 15.4 0.5 0.63 9.7 0.1 2.1 2 0 0 2 2 2 0 Syntaxin SPARC_Ca_bdg PF10591.9 KFO98827.1 - 0.022 15.1 0.5 0.054 13.8 0.1 1.7 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2267 PF10025.9 KFO98827.1 - 0.065 13.5 0.0 21 5.4 0.0 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2267) Homeobox_KN PF05920.11 KFO98828.1 - 0.0012 18.7 3.1 0.0019 18.1 3.1 1.3 1 0 0 1 1 1 1 Homeobox KN domain AdoHcyase PF05221.17 KFO98829.1 - 5.5e-136 452.6 0.0 1e-72 244.8 0.2 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KFO98829.1 - 1.4e-85 285.3 3.4 2.3e-85 284.6 3.4 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KFO98829.1 - 8.5e-10 38.3 0.1 1.5e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KFO98829.1 - 8.3e-06 25.5 0.2 1.4e-05 24.8 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KFO98829.1 - 0.0029 17.9 0.1 0.0065 16.7 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.18 KFO98829.1 - 0.1 12.5 0.9 0.25 11.2 0.9 1.8 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Agouti PF05039.12 KFO98830.1 - 2.4e-22 79.4 11.7 3.6e-22 78.9 11.7 1.3 1 0 0 1 1 1 1 Agouti protein Toxin_9 PF02819.15 KFO98830.1 - 5.4 7.4 18.2 4.1 7.8 16.5 1.7 2 0 0 2 2 2 0 Spider toxin Yae1_N PF09811.9 KFO98831.1 - 8.9e-15 54.1 46.1 1.8e+04 -11.3 46.1 4.8 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Trypsin PF00089.26 KFO98832.1 - 1.2e-20 74.3 0.1 1.2e-20 74.2 0.1 1.0 1 0 0 1 1 1 1 Trypsin Ras PF00071.22 KFO98833.1 - 1.1e-31 109.7 0.0 1.3e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO98833.1 - 5.3e-24 84.7 0.0 9.3e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO98833.1 - 4.9e-08 32.6 0.0 7.5e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFO98833.1 - 3e-06 26.9 0.0 9.1e-06 25.3 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFO98833.1 - 2.6e-05 23.7 0.1 4.7e-05 22.9 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1_Xtn PF16897.5 KFO98833.1 - 0.013 15.5 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain ATP_bind_1 PF03029.17 KFO98833.1 - 0.021 14.6 0.1 0.026 14.3 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein NDK PF00334.19 KFO98834.1 - 3.6e-17 62.6 0.0 4.6e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase TFA2_Winged_2 PF18121.1 KFO98835.1 - 0.32 10.7 3.5 2.3 8.0 0.2 4.6 2 1 1 3 3 3 0 TFA2 Winged helix domain 2 Ank_4 PF13637.6 KFO98836.1 - 7.1e-27 93.4 4.3 2.9e-10 40.5 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFO98836.1 - 2.8e-25 88.0 8.6 7e-10 39.0 0.2 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFO98836.1 - 3.5e-25 88.4 1.2 6.3e-14 52.3 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFO98836.1 - 4.9e-24 83.7 6.4 3.8e-07 30.3 1.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KFO98836.1 - 7.8e-21 72.0 4.1 4.9e-06 26.5 0.2 4.1 4 0 0 4 4 4 4 Ankyrin repeat rve PF00665.26 KFO98837.1 - 2e-28 99.0 0.1 5.6e-28 97.5 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Integrase_Zn PF02022.19 KFO98837.1 - 1e-12 47.8 2.1 2.7e-12 46.4 2.1 1.8 1 0 0 1 1 1 1 Integrase Zinc binding domain RNase_H PF00075.24 KFO98837.1 - 1.2e-06 28.7 0.0 2.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 RNase H DDE_Tnp_IS240 PF13610.6 KFO98837.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 DDE domain GDE_C PF06202.14 KFO98837.1 - 0.092 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase rve_3 PF13683.6 KFO98837.1 - 0.093 12.5 0.1 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain Keratin PF02422.16 KFO98839.1 - 2.1e-33 113.9 8.5 2.2e-33 113.8 8.5 1.0 1 0 0 1 1 1 1 Keratin DUF4686 PF15742.5 KFO98840.1 - 1.7e-84 284.2 92.7 4.2e-84 282.9 92.7 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4686) Beta-lactamase PF00144.24 KFO98841.1 - 5.9e-37 127.6 0.0 8.6e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Pkinase_Tyr PF07714.17 KFO98842.1 - 1.5e-99 332.5 0.0 1.7e-99 332.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO98842.1 - 2.3e-49 168.1 0.0 2.8e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.6 KFO98842.1 - 1.5e-13 51.5 1.0 2.6e-13 50.6 1.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Haspin_kinase PF12330.8 KFO98842.1 - 0.008 15.2 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFO98842.1 - 0.023 14.0 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFO98842.1 - 0.097 11.4 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Collagen PF01391.18 KFO98844.1 - 1.1e-17 63.5 54.0 2.4e-10 40.0 26.7 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) C1q PF00386.21 KFO98844.1 - 2.5e-14 53.6 0.0 2.9e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 C1q domain C1q PF00386.21 KFO98845.1 - 5.3e-33 113.9 0.0 6.3e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFO98845.1 - 4.7e-12 45.5 36.9 8.3e-08 31.9 21.8 2.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) BclA_C PF18573.1 KFO98845.1 - 0.00031 20.7 0.1 0.00048 20.0 0.1 1.3 1 0 0 1 1 1 1 BclA C-terminal domain Pkinase_Tyr PF07714.17 KFO98846.1 - 5.9e-93 310.9 0.0 8.3e-93 310.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.19 KFO98846.1 - 2.7e-66 223.0 0.0 4.2e-66 222.4 0.0 1.3 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.25 KFO98846.1 - 5.6e-45 153.8 0.0 8.1e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 KFO98846.1 - 7e-33 112.8 0.1 1.8e-16 60.2 0.1 2.9 3 0 0 3 3 3 2 Fibronectin type III domain SAM_1 PF00536.30 KFO98846.1 - 6.7e-20 71.3 0.1 1.2e-19 70.5 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EphA2_TM PF14575.6 KFO98846.1 - 6.8e-18 65.3 0.0 1.4e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SAM_2 PF07647.17 KFO98846.1 - 2.8e-16 59.4 0.0 6.2e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pur_ac_phosph_N PF16656.5 KFO98846.1 - 5.1e-08 33.4 0.2 1.5e-06 28.6 0.2 2.5 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.5 KFO98846.1 - 8.3e-07 29.1 0.1 0.00072 19.7 0.0 2.6 2 0 0 2 2 2 2 Fibronectin type III domain SusE PF14292.6 KFO98846.1 - 3.3e-06 27.3 0.0 0.0047 17.1 0.3 2.4 2 0 0 2 2 2 2 SusE outer membrane protein Ephrin_rec_like PF07699.13 KFO98846.1 - 0.00042 20.0 5.7 0.00042 20.0 5.7 2.3 2 0 0 2 2 2 1 Putative ephrin-receptor like Kdo PF06293.14 KFO98846.1 - 0.0059 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Interfer-bind PF09294.10 KFO98846.1 - 0.008 16.5 0.1 0.041 14.2 0.0 2.1 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III Haspin_kinase PF12330.8 KFO98846.1 - 0.0091 15.0 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain DUF2369 PF10179.9 KFO98846.1 - 0.048 14.0 0.1 3.3 8.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) DUF3300 PF11737.8 KFO98846.1 - 0.08 12.5 1.3 6.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3300) wnt PF00110.19 KFO98848.1 - 3.9e-131 437.2 23.7 4.4e-131 437.1 23.7 1.0 1 0 0 1 1 1 1 wnt family Ras PF00071.22 KFO98849.1 - 2.9e-50 170.0 0.0 3.2e-50 169.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO98849.1 - 5.6e-20 71.7 0.0 7.7e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO98849.1 - 2.2e-06 27.3 0.0 2.4e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PET117 PF15786.5 KFO98849.1 - 0.00047 20.4 0.0 0.00064 19.9 0.0 1.2 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial DUF2452 PF10504.9 KFO98850.1 - 2.7e-57 192.6 0.2 3.1e-57 192.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2452) PMP22_Claudin PF00822.20 KFO98851.1 - 5.5e-25 88.2 3.8 7e-25 87.8 3.8 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFO98851.1 - 4.8e-10 39.5 6.5 5.6e-10 39.3 6.5 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.11 KFO98851.1 - 0.11 12.4 4.8 0.056 13.3 3.1 1.4 1 1 1 2 2 2 0 Amastin surface glycoprotein Phage_holin_5_2 PF16079.5 KFO98851.1 - 0.14 12.5 2.2 0.25 11.7 1.6 1.7 1 1 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V Mntp PF02659.15 KFO98851.1 - 0.2 11.4 3.7 0.21 11.3 2.2 1.7 2 0 0 2 2 2 0 Putative manganese efflux pump DUF2207 PF09972.9 KFO98851.1 - 0.25 10.1 0.3 0.27 10.0 0.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4064 PF13273.6 KFO98851.1 - 0.97 9.7 8.9 3.9 7.8 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) PMP22_Claudin PF00822.20 KFO98852.1 - 1.2e-16 61.1 7.0 1.4e-16 60.8 7.0 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFO98852.1 - 2.2e-12 47.1 8.7 5.4e-12 45.9 8.7 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HMGIC_fpl PF10242.9 KFO98852.1 - 0.011 16.0 5.4 0.018 15.2 5.4 1.5 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein FAM70 PF14967.6 KFO98852.1 - 0.028 13.9 0.1 0.033 13.7 0.1 1.2 1 0 0 1 1 1 0 FAM70 protein TMEM100 PF16311.5 KFO98852.1 - 0.055 13.1 0.2 0.1 12.2 0.2 1.4 1 0 0 1 1 1 0 Transmembrane protein 100 CSD PF00313.22 KFO98853.1 - 1.9e-26 91.7 0.5 3.2e-26 90.9 0.5 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KFO98853.1 - 0.0091 15.7 0.0 0.026 14.2 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease B OB domain DNA_pol_A_exo1 PF01612.20 KFO98854.1 - 4.3e-48 163.3 1.1 4.3e-48 163.3 1.1 1.6 2 0 0 2 2 2 1 3'-5' exonuclease PMC2NT PF08066.12 KFO98854.1 - 1.6e-22 80.0 0.0 1.2e-21 77.1 0.0 2.5 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 KFO98854.1 - 2.1e-14 53.2 0.6 2.7e-13 49.7 0.0 2.4 2 0 0 2 2 2 1 HRDC domain DUF5072 PF16807.5 KFO98854.1 - 0.045 13.8 0.1 0.15 12.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5072) FAM70 PF14967.6 KFO98854.1 - 1.6 8.1 6.3 4 6.8 6.3 1.6 1 0 0 1 1 1 0 FAM70 protein DUF4407 PF14362.6 KFO98854.1 - 3.6 6.9 6.8 5.8 6.2 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UbiA PF01040.18 KFO98855.1 - 3e-40 138.1 11.6 3.8e-40 137.8 11.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Patched PF02460.18 KFO98857.1 - 1.1e-20 73.4 25.2 2.5e-16 59.0 2.3 2.4 2 0 0 2 2 2 2 Patched family MMPL PF03176.15 KFO98857.1 - 1.8e-13 50.2 30.6 2.4e-09 36.6 5.9 2.3 2 0 0 2 2 2 2 MMPL family Sterol-sensing PF12349.8 KFO98857.1 - 1.1e-12 48.1 10.9 1.1e-12 48.1 10.9 3.1 3 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 KFO98857.1 - 0.0061 14.3 7.3 0.012 13.3 7.3 1.4 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family RELT PF12606.8 KFO98857.1 - 0.18 10.8 1.7 0.97 8.5 1.7 2.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 FBA PF04300.13 KFO98858.1 - 7.2e-80 266.9 0.3 9.1e-80 266.5 0.3 1.1 1 0 0 1 1 1 1 F-box associated region F-box PF00646.33 KFO98858.1 - 1.2e-09 37.8 0.8 2e-09 37.1 0.8 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFO98858.1 - 1.3e-06 28.1 1.8 3.5e-06 26.8 1.8 1.7 1 0 0 1 1 1 1 F-box-like FBA PF04300.13 KFO98859.1 - 5.2e-74 247.8 0.2 6.9e-74 247.4 0.2 1.2 1 0 0 1 1 1 1 F-box associated region F-box-like PF12937.7 KFO98859.1 - 9e-11 41.5 2.9 2e-10 40.4 2.9 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFO98859.1 - 1.5e-07 31.1 1.9 2.8e-07 30.2 1.9 1.5 1 0 0 1 1 1 1 F-box domain HORMA PF02301.18 KFO98860.1 - 1.5e-09 37.8 0.1 2.7e-09 36.9 0.1 1.3 1 1 0 1 1 1 1 HORMA domain Draxin PF15550.6 KFO98861.1 - 3.7e-139 464.1 9.8 4.1e-139 463.9 9.8 1.0 1 0 0 1 1 1 1 Draxin Dickkopf_N PF04706.12 KFO98861.1 - 5.1 7.6 14.3 11 6.6 14.3 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region AGTRAP PF06396.11 KFO98862.1 - 9.7e-57 190.9 2.2 1.1e-56 190.8 2.2 1.0 1 0 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) MTHFR PF02219.17 KFO98863.1 - 5.4e-119 396.8 0.0 7.1e-119 396.4 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Voltage_CLC PF00654.20 KFO98864.1 - 7.5e-97 324.7 25.7 9.1e-97 324.5 18.0 2.1 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 KFO98864.1 - 9.6e-15 54.8 0.2 2e-08 34.6 0.0 2.7 2 0 0 2 2 2 2 CBS domain ANP PF00212.18 KFO98865.1 - 3.6e-14 52.6 9.8 5.5e-14 52.1 9.8 1.3 1 0 0 1 1 1 1 Atrial natriuretic peptide ABC_tran_CTD PF16326.5 KFO98865.1 - 0.032 14.5 3.8 0.046 14.0 3.8 1.2 1 0 0 1 1 1 0 ABC transporter C-terminal domain Guanylate_cyc PF00211.20 KFO98866.1 - 1.9e-68 229.7 0.0 2.2e-68 229.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KFO98866.1 - 6.9e-05 22.4 1.2 0.00012 21.7 1.2 1.4 1 0 0 1 1 1 1 Heme NO binding associated Trypsin PF00089.26 KFO98867.1 - 4e-68 229.5 0.6 4.5e-68 229.4 0.6 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFO98867.1 - 2.6e-07 31.6 0.0 3.8e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFO98867.1 - 0.0019 18.6 0.1 0.003 17.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF2152 PF10222.9 KFO98868.1 - 2.3e-171 571.2 0.4 2.6e-171 571.0 0.4 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2152) EF-hand_13 PF17958.1 KFO98868.1 - 0.16 11.8 0.3 0.87 9.4 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain 2OG-FeII_Oxy PF03171.20 KFO98869.1 - 2.2e-06 28.1 0.0 5.2e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Anp1 PF03452.14 KFO98869.1 - 5.1e-06 26.1 0.0 0.097 12.1 0.0 3.0 3 0 0 3 3 3 2 Anp1 2OG-FeII_Oxy_3 PF13640.6 KFO98869.1 - 3.8e-05 24.5 0.1 0.00013 22.8 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Fzo_mitofusin PF04799.13 KFO98870.1 - 1.6e-76 255.3 8.7 8e-75 249.8 3.1 2.7 2 0 0 2 2 2 2 fzo-like conserved region Dynamin_N PF00350.23 KFO98870.1 - 1.6e-23 83.6 0.6 9.7e-23 81.0 0.0 2.6 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 KFO98870.1 - 7.2e-08 32.5 0.0 3.9e-07 30.2 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Apolipoprotein PF01442.18 KFO98870.1 - 0.13 12.2 7.8 0.25 11.2 3.1 2.7 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Streptin-Immun PF11083.8 KFO98870.1 - 0.37 11.2 4.0 0.21 12.0 0.2 2.4 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein Synaptobrevin PF00957.21 KFO98870.1 - 0.44 10.4 2.5 1.2 9.0 0.1 2.5 2 0 0 2 2 2 0 Synaptobrevin Baculo_PEP_C PF04513.12 KFO98870.1 - 0.7 9.9 2.6 16 5.5 0.2 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GTP_EFTU PF00009.27 KFO98870.1 - 1.9 8.0 3.8 60 3.1 3.8 2.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain MIIP PF15734.5 KFO98871.1 - 2.3e-45 155.6 0.2 2.6e-45 155.4 0.2 1.1 1 0 0 1 1 1 1 Migration and invasion-inhibitory TNFR_c6 PF00020.18 KFO98872.1 - 2e-12 47.3 45.8 3.9e-05 23.9 1.2 4.6 4 0 0 4 4 4 4 TNFR/NGFR cysteine-rich region Yae1_N PF09811.9 KFO98873.1 - 7.7e-18 63.9 63.5 1.8e+04 -28.3 63.5 6.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Hus1 PF04005.12 KFO98875.1 - 0.0088 15.2 0.0 0.0088 15.2 0.0 1.1 1 0 0 1 1 1 1 Hus1-like protein adh_short PF00106.25 KFO98876.1 - 1.1e-34 119.6 0.0 1.7e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFO98876.1 - 3e-23 82.6 0.0 8.5e-23 81.1 0.0 1.7 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFO98876.1 - 1.2e-13 51.3 0.2 3.6e-13 49.8 0.2 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFO98876.1 - 4.9e-07 29.2 0.0 6.7e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KFO98876.1 - 0.011 15.2 0.1 0.016 14.7 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KFO98876.1 - 0.028 14.5 0.1 0.052 13.6 0.1 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase zf-RING_5 PF14634.6 KFO98876.1 - 0.16 12.0 0.9 0.65 10.0 0.2 2.1 2 0 0 2 2 2 0 zinc-RING finger domain Abhydrolase_3 PF07859.13 KFO98877.1 - 4.6e-55 186.8 0.0 4.8e-42 144.2 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 KFO98877.1 - 1.5e-07 30.7 0.1 1e-06 27.9 0.1 1.9 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KFO98877.1 - 0.0004 19.4 0.0 0.00058 18.8 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KFO98877.1 - 0.041 13.4 0.0 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2920 PF11144.8 KFO98877.1 - 0.18 11.0 0.0 2.4 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Abhydrolase_3 PF07859.13 KFO98878.1 - 6.3e-47 160.2 0.0 1e-33 117.0 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 KFO98878.1 - 0.0012 17.8 0.3 0.0072 15.2 0.3 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KFO98878.1 - 0.0028 17.2 0.0 0.0055 16.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 KFO98878.1 - 0.1 11.3 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF2920 PF11144.8 KFO98878.1 - 0.24 10.5 0.2 3.9 6.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) LRR_8 PF13855.6 KFO98880.1 - 3.7e-44 148.3 30.6 5.2e-14 51.8 4.3 3.2 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFO98880.1 - 1.4e-14 54.0 15.1 1e-05 25.8 4.5 4.7 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFO98880.1 - 9.6e-10 38.5 1.2 2.8e-09 37.0 0.0 2.1 1 1 1 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFO98880.1 - 5.9e-07 29.2 10.0 0.53 11.0 0.0 6.5 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_9 PF14580.6 KFO98880.1 - 1.1e-06 28.2 3.0 7.7e-05 22.3 1.2 2.1 1 1 1 2 2 2 2 Leucine-rich repeat DUF3557 PF12078.8 KFO98880.1 - 0.11 12.5 0.1 0.3 11.0 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3557) LRR_3 PF07725.12 KFO98880.1 - 0.17 11.8 5.4 4.2 7.4 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat LRRNT PF01462.18 KFO98880.1 - 0.22 11.2 3.8 0.91 9.2 3.8 2.1 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 KFO98880.1 - 0.29 11.3 0.2 0.29 11.3 0.2 5.1 6 0 0 6 6 6 0 Leucine Rich repeat Podoplanin PF05808.11 KFO98881.1 - 8.3e-25 87.8 0.6 2.2e-24 86.4 0.5 1.6 1 1 0 1 1 1 1 Podoplanin VSP PF03302.13 KFO98881.1 - 0.052 12.4 0.4 0.061 12.2 0.4 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein zf-C2H2 PF00096.26 KFO98882.1 - 1.1e-18 66.6 61.3 0.0026 18.1 2.0 8.7 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO98882.1 - 5.8e-17 60.9 59.2 0.0052 17.5 2.4 8.9 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFO98882.1 - 9.8e-11 41.4 43.8 0.0036 17.3 3.1 7.3 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO98882.1 - 0.00027 21.1 27.5 0.23 11.8 0.7 6.9 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KFO98882.1 - 0.017 15.5 0.3 0.017 15.5 0.3 7.2 6 1 0 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger zf-CHCC PF10276.9 KFO98882.1 - 0.59 10.2 8.6 6.3 6.9 0.1 4.0 4 0 0 4 4 3 0 Zinc-finger domain DUF678 PF05077.12 KFO98882.1 - 0.61 10.3 10.9 1.1 9.5 0.2 5.5 4 1 1 5 5 5 0 Protein of unknown function (DUF678) PyrI_C PF02748.15 KFO98882.1 - 0.75 9.8 21.6 0.48 10.4 0.2 6.4 6 1 1 7 7 7 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-MYST PF17772.1 KFO98882.1 - 1.1 8.9 16.2 2.2 8.0 0.3 5.4 5 0 0 5 5 5 0 MYST family zinc finger domain zf-C2H2_11 PF16622.5 KFO98882.1 - 1.7 8.5 40.7 0.017 14.9 1.0 7.1 8 0 0 8 8 8 0 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KFO98882.1 - 1.8 9.3 31.5 18 6.0 0.5 8.2 5 3 2 7 7 7 0 Zinc finger C2H2-type, 3 repeats PhnA_Zn_Ribbon PF08274.12 KFO98882.1 - 2.4 8.2 5.6 22 5.1 0.5 3.3 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-C2H2_8 PF15909.5 KFO98882.1 - 2.9 8.3 19.7 0.15 12.4 1.5 4.3 4 0 0 4 4 4 0 C2H2-type zinc ribbon zinc_ribbon_9 PF14369.6 KFO98882.1 - 3.6 7.9 10.0 4 7.8 0.1 4.3 4 0 0 4 4 4 0 zinc-ribbon HypA PF01155.19 KFO98882.1 - 4.2 7.4 15.7 7 6.7 0.2 5.0 4 1 1 5 5 5 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF148 PF02520.17 KFO98883.1 - 0.025 14.7 0.1 0.029 14.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF148 Glu_dehyd_C PF16912.5 KFO98883.1 - 0.14 11.6 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus DUF148 PF02520.17 KFO98884.1 - 0.0061 16.7 7.5 0.021 14.9 7.5 1.9 1 0 0 1 1 1 1 Domain of unknown function DUF148 FPP PF05911.11 KFO98884.1 - 0.022 13.0 23.2 0.039 12.2 23.2 1.4 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil TMF_TATA_bd PF12325.8 KFO98884.1 - 0.36 11.0 35.3 0.46 10.7 14.7 4.3 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding Golgin_A5 PF09787.9 KFO98884.1 - 0.69 9.3 28.7 1.9 7.9 28.7 1.7 1 1 0 1 1 1 0 Golgin subfamily A member 5 DivIC PF04977.15 KFO98884.1 - 2.2 8.1 34.3 1.8 8.4 0.1 4.6 3 1 2 5 5 5 0 Septum formation initiator ERM PF00769.19 KFO98884.1 - 4.3 7.1 42.7 0.019 14.8 19.8 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF1192 PF06698.11 KFO98884.1 - 4.5 7.4 18.7 0.24 11.5 2.7 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1192) CENP-F_leu_zip PF10473.9 KFO98884.1 - 4.9 7.2 40.8 1.5 8.9 13.2 3.4 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 KFO98884.1 - 5.7 7.0 43.5 0.018 15.1 23.1 3.3 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KFO98884.1 - 6.2 5.6 34.4 6.2 5.6 14.5 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein TMEM51 PF15345.6 KFO98885.1 - 7.5e-83 278.0 0.2 8.6e-83 277.8 0.2 1.0 1 0 0 1 1 1 1 Transmembrane protein 51 TMEM61 PF15105.6 KFO98885.1 - 0.00012 21.9 2.8 0.00077 19.3 0.2 2.9 2 1 1 3 3 3 1 TMEM61 protein family WBP-1 PF11669.8 KFO98885.1 - 0.018 15.6 0.5 1.8 9.2 0.0 3.0 2 1 0 2 2 2 0 WW domain-binding protein 1 PRAS PF15798.5 KFO98885.1 - 0.065 13.8 1.1 0.11 13.1 1.1 1.5 1 0 0 1 1 1 0 Proline-rich AKT1 substrate 1 DUF1418 PF07214.12 KFO98885.1 - 0.084 12.7 0.1 0.42 10.5 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1418) Tetraspanin PF00335.20 KFO98885.1 - 0.2 11.3 0.2 0.31 10.7 0.2 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF202 PF02656.15 KFO98885.1 - 6.6 7.3 6.1 46 4.5 6.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF202) YqgF PF14639.6 KFO98886.1 - 0.01 15.6 0.1 0.012 15.4 0.1 1.3 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 FapA PF03961.13 KFO98886.1 - 0.013 14.2 1.8 0.013 14.1 1.8 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A EF-hand_1 PF00036.32 KFO98888.1 - 3.3e-07 29.4 7.1 0.0011 18.4 0.7 2.7 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KFO98888.1 - 5.5e-05 23.5 1.7 7.6e-05 23.1 0.4 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KFO98888.1 - 6e-05 22.7 1.8 0.033 14.1 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KFO98888.1 - 0.0039 17.0 2.5 0.014 15.2 2.5 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KFO98888.1 - 0.51 9.9 0.1 0.51 9.9 0.1 2.9 4 0 0 4 4 4 0 EF hand Trypsin PF00089.26 KFO98889.1 - 1.5e-68 230.9 0.5 1.7e-68 230.7 0.5 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFO98889.1 - 3.2e-07 31.4 0.0 5e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFO98889.1 - 0.011 16.1 0.1 0.031 14.6 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) Peptidase_C14 PF00656.22 KFO98890.1 - 4e-47 161.3 0.0 5e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 Caspase domain CARD PF00619.21 KFO98890.1 - 1.5e-12 47.4 0.1 2.5e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 KFO98890.1 - 0.067 13.2 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Caspase recruitment domain Pkinase PF00069.25 KFO98891.1 - 2.5e-24 86.1 0.0 5.6e-24 84.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO98891.1 - 3e-14 52.9 0.0 9.8e-14 51.2 0.0 1.8 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 KFO98891.1 - 0.00077 18.9 0.0 0.003 16.9 0.0 2.0 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 KFO98891.1 - 0.047 13.6 0.1 0.084 12.8 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family dCMP_cyt_deam_1 PF00383.23 KFO98892.1 - 4e-16 58.7 0.2 4.9e-16 58.5 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KFO98892.1 - 1.4e-12 48.0 1.8 7.8e-10 39.1 0.1 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Dynactin_p62 PF05502.13 KFO98892.1 - 0.0083 15.0 0.4 0.01 14.7 0.4 1.0 1 0 0 1 1 1 1 Dynactin p62 family LmjF365940-deam PF14421.6 KFO98892.1 - 0.082 12.5 2.0 1.5 8.3 0.2 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases PID_2 PF14719.6 KFO98893.1 - 7.6e-55 185.6 0.4 8.9e-55 185.4 0.4 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.23 KFO98893.1 - 0.00033 20.7 0.0 0.00049 20.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Glyco_hydro_65C PF03633.15 KFO98893.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain GIDE PF12483.8 KFO98894.1 - 2.3e-22 79.1 0.0 4.1e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 E3 Ubiquitin ligase zf-C3HC4_3 PF13920.6 KFO98894.1 - 2.8e-12 46.3 14.3 4.3e-12 45.7 14.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFO98894.1 - 9.9e-05 22.1 14.0 0.00017 21.3 14.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KFO98894.1 - 0.0004 20.7 15.6 0.00067 19.9 15.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFO98894.1 - 0.0022 17.9 14.6 0.0039 17.1 14.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain LapA_dom PF06305.11 KFO98894.1 - 0.0083 15.9 1.1 0.013 15.3 1.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Vps39_2 PF10367.9 KFO98894.1 - 0.22 12.0 3.5 1.2 9.6 3.5 2.1 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.6 KFO98894.1 - 0.22 11.4 14.4 0.39 10.6 14.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) VWA_3 PF13768.6 KFO98895.1 - 6.1e-27 94.5 0.0 1.1e-26 93.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KFO98895.1 - 9.6e-26 89.5 0.0 2e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VIT PF08487.10 KFO98895.1 - 1.3e-07 31.8 0.0 2.9e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 KFO98895.1 - 1.2e-06 29.1 0.0 2.9e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KFO98895.1 - 2.2e-05 24.8 0.0 3.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Pox_LP_H2 PF03356.15 KFO98895.1 - 0.068 13.0 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Viral late protein H2 DEAD PF00270.29 KFO98896.1 - 4.2e-27 95.0 0.0 7.3e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFO98896.1 - 2.9e-26 92.0 0.0 9.1e-26 90.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFO98896.1 - 8.3e-05 22.7 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UBX PF00789.20 KFO98897.1 - 2.9e-08 33.8 0.0 5e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain Gag_p30 PF02093.16 KFO98898.1 - 8.3e-16 58.1 0.2 1.1e-15 57.7 0.2 1.1 1 0 0 1 1 1 1 Gag P30 core shell protein Gag_p24 PF00607.20 KFO98898.1 - 0.0054 16.6 0.0 0.0081 16.0 0.0 1.5 1 1 0 1 1 1 1 gag gene protein p24 (core nucleocapsid protein) DUF577 PF04510.12 KFO98899.1 - 0.031 14.2 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF577) KRBA1 PF15287.6 KFO98899.1 - 0.46 10.2 1.8 10 5.9 0.4 2.4 2 0 0 2 2 2 0 KRBA1 family repeat TUDOR PF00567.24 KFO98900.1 - 4.1e-22 78.5 0.0 9.1e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 Tudor domain KH_1 PF00013.29 KFO98900.1 - 1.3e-07 31.3 0.0 2.9e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 KH domain Agenet PF05641.12 KFO98900.1 - 0.012 16.1 0.1 0.028 14.9 0.1 1.7 1 0 0 1 1 1 0 Agenet domain KH_4 PF13083.6 KFO98900.1 - 0.04 13.8 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 KH domain RRM_1 PF00076.22 KFO98901.1 - 0.12 12.2 0.4 0.28 11.0 0.1 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MRP-S23 PF10484.9 KFO98902.1 - 2.4e-11 44.0 0.0 2.6e-11 43.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S23 CUE PF02845.16 KFO98903.1 - 2.8e-15 55.7 0.2 5.4e-15 54.8 0.2 1.5 1 0 0 1 1 1 1 CUE domain zf-C2H2_4 PF13894.6 KFO98904.1 - 1.3e-15 56.7 55.5 0.0024 18.6 1.4 6.9 7 0 0 7 7 6 5 C2H2-type zinc finger zf-C2H2 PF00096.26 KFO98904.1 - 3.5e-15 55.5 54.8 0.0026 18.1 5.9 7.0 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO98904.1 - 1.5e-10 41.0 61.6 0.00027 21.2 3.4 8.7 9 0 0 9 9 9 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFO98904.1 - 2.1e-05 24.7 26.3 0.17 12.2 0.7 6.4 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-WRNIP1_ubi PF18279.1 KFO98904.1 - 0.00017 22.0 0.6 0.14 12.9 0.0 4.2 3 0 0 3 3 3 1 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-C2H2_6 PF13912.6 KFO98904.1 - 0.0079 16.2 0.4 0.0079 16.2 0.4 7.7 9 0 0 9 9 9 3 C2H2-type zinc finger FYVE PF01363.21 KFO98904.1 - 0.0081 16.3 27.0 0.69 10.1 8.9 4.6 2 1 2 4 4 4 1 FYVE zinc finger zf-Di19 PF05605.12 KFO98904.1 - 0.012 15.9 34.2 0.63 10.4 6.7 4.5 3 1 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 KFO98904.1 - 0.029 14.4 2.6 0.029 14.4 2.6 6.6 4 2 3 7 7 7 0 BED zinc finger BolA PF01722.18 KFO98904.1 - 0.047 14.0 5.8 4.8 7.5 0.2 3.6 3 0 0 3 3 3 0 BolA-like protein zf_C2H2_13 PF18508.1 KFO98904.1 - 0.12 12.0 0.1 0.12 12.0 0.1 3.3 3 0 0 3 3 3 0 Zinc finger domain zf-C2H2_2 PF12756.7 KFO98904.1 - 0.21 11.9 31.5 1.3 9.4 0.0 6.2 2 1 3 6 6 6 0 C2H2 type zinc-finger (2 copies) WASH-7_C PF14746.6 KFO98904.1 - 0.22 11.2 1.0 0.33 10.6 1.0 1.2 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal Elf1 PF05129.13 KFO98904.1 - 2.2 8.4 31.0 1.1 9.3 3.7 5.6 2 1 3 5 5 5 0 Transcription elongation factor Elf1 like DZR PF12773.7 KFO98904.1 - 3.2 7.9 25.8 48 4.1 6.6 4.5 2 1 1 3 3 3 0 Double zinc ribbon zf-C2H2_8 PF15909.5 KFO98904.1 - 7.5 6.9 16.4 0.85 10.0 4.5 3.5 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-FCS PF06467.14 KFO98904.1 - 9.9 6.2 24.6 15 5.6 0.1 6.7 5 2 2 7 7 7 0 MYM-type Zinc finger with FCS sequence motif Dynein_light PF01221.18 KFO98905.1 - 5.2e-44 148.5 2.1 5.8e-44 148.3 2.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Nop PF01798.18 KFO98905.1 - 0.067 12.7 0.0 0.074 12.5 0.0 1.0 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin Ectatomin PF06457.11 KFO98905.1 - 0.15 12.0 0.2 0.25 11.3 0.2 1.4 1 0 0 1 1 1 0 Ectatomin DUF4042 PF13251.6 KFO98906.1 - 1.1e-69 233.8 0.1 1.1e-69 233.8 0.1 4.5 6 0 0 6 6 6 1 Domain of unknown function (DUF4042) HEAT_2 PF13646.6 KFO98906.1 - 3.9e-22 78.4 1.3 6.2e-07 29.7 0.1 7.1 4 1 3 7 7 7 5 HEAT repeats HEAT PF02985.22 KFO98906.1 - 7.9e-17 59.9 17.5 0.00015 21.7 0.0 9.7 10 0 0 10 10 9 4 HEAT repeat HEAT_EZ PF13513.6 KFO98906.1 - 2.6e-15 56.5 23.1 0.0045 17.5 0.1 8.9 9 2 2 11 11 9 5 HEAT-like repeat Cnd1 PF12717.7 KFO98906.1 - 9.7e-07 29.0 4.5 0.057 13.5 0.1 4.8 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KFO98906.1 - 3.5e-06 25.9 5.0 0.12 10.9 0.1 4.4 4 0 0 4 4 4 3 Adaptin N terminal region RTP1_C1 PF10363.9 KFO98906.1 - 7.8e-05 22.8 2.0 1.7 8.8 0.0 4.6 4 1 1 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_PBS PF03130.16 KFO98906.1 - 0.0011 19.4 8.0 0.98 10.3 0.0 6.9 6 1 0 6 6 5 1 PBS lyase HEAT-like repeat Arm PF00514.23 KFO98906.1 - 0.014 15.4 28.8 0.043 13.9 0.1 8.0 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat MMS19_N PF14500.6 KFO98906.1 - 0.019 14.6 1.6 0.47 10.0 0.2 3.8 2 1 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II FANCI_S2 PF14676.6 KFO98906.1 - 0.069 13.4 1.5 16 5.7 0.0 3.2 3 0 0 3 3 2 0 FANCI solenoid 2 RasGEF_N_2 PF14663.6 KFO98906.1 - 1.8 9.0 8.9 4.8 7.6 0.1 3.6 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HNF-1B_C PF04812.13 KFO98907.1 - 2.1e-119 397.7 39.7 3.3e-119 397.1 39.7 1.3 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus HNF-1_N PF04814.13 KFO98907.1 - 1.7e-35 123.4 0.3 1.7e-35 123.4 0.3 3.0 4 1 0 4 4 4 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Homeodomain PF00046.29 KFO98907.1 - 2.5e-05 24.0 1.7 0.00026 20.8 1.7 2.6 1 1 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO98907.1 - 0.02 14.8 0.0 0.14 12.1 0.0 2.4 2 1 0 2 2 2 0 Homeobox KN domain DEAD PF00270.29 KFO98908.1 - 1.7e-38 132.1 0.0 3.5e-38 131.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFO98908.1 - 4e-21 75.4 0.1 1.5e-18 67.2 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KFO98908.1 - 1.4e-06 28.4 2.0 2.4e-06 27.7 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KFO98908.1 - 0.00078 19.8 0.0 0.0019 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain EF-hand_4 PF12763.7 KFO98909.1 - 0.024 14.6 0.0 0.065 13.2 0.0 1.7 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Myb_DNA-binding PF00249.31 KFO98910.1 - 2.6e-10 40.3 0.1 6.6e-10 39.0 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 KFO98910.1 - 4.5e-08 33.3 0.0 1.8e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 KFO98910.1 - 9e-06 25.8 0.5 5.4e-05 23.4 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain LIM PF00412.22 KFO98911.1 - 1.5e-32 111.6 24.9 8.2e-18 64.4 2.1 2.5 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 KFO98911.1 - 3.2e-10 39.7 0.1 5.9e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 Homeodomain SpoIIIAH PF12685.7 KFO98911.1 - 2.4 7.9 5.8 3.2 7.5 5.8 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein TLV_coat PF00429.19 KFO98912.1 - 0.0041 15.9 1.7 0.0049 15.6 1.7 1.1 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) SecE PF00584.20 KFO98913.1 - 6.4e-17 61.2 0.1 8.1e-17 60.9 0.1 1.2 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Pkinase_Tyr PF07714.17 KFO98914.1 - 3.7e-89 298.4 0.0 5.5e-89 297.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.24 KFO98914.1 - 1.9e-51 172.9 0.6 4e-27 94.5 0.0 2.5 2 0 0 2 2 2 2 Receptor L domain GF_recep_IV PF14843.6 KFO98914.1 - 5e-42 142.8 80.7 3.6e-32 110.9 25.4 5.0 2 2 2 4 4 4 2 Growth factor receptor domain IV Pkinase PF00069.25 KFO98914.1 - 4.7e-40 137.6 0.0 7e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.20 KFO98914.1 - 7.8e-33 113.5 84.3 3.7e-30 104.8 42.4 4.2 2 1 2 4 4 4 3 Furin-like cysteine rich region APH PF01636.23 KFO98914.1 - 0.02 14.8 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFO98914.1 - 0.066 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KFO98914.1 - 0.14 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like SMG1 PF15785.5 KFO98914.1 - 0.18 10.1 0.1 0.27 9.6 0.1 1.1 1 0 0 1 1 1 0 Serine/threonine-protein kinase smg-1 LANC_like PF05147.13 KFO98915.1 - 3.8e-99 331.6 0.4 4.4e-99 331.4 0.4 1.0 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Glyco_hydro_88 PF07470.13 KFO98915.1 - 0.0018 17.4 1.2 0.02 14.0 0.1 2.5 1 1 0 2 2 2 1 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 KFO98915.1 - 0.0021 17.6 0.1 0.73 9.3 0.0 2.9 3 0 0 3 3 3 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_127 PF07944.12 KFO98915.1 - 0.011 14.3 0.4 0.14 10.6 0.2 2.3 2 1 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 TMEM52 PF14979.6 KFO98916.1 - 0.054 13.4 9.3 0.15 12.0 1.8 2.2 2 0 0 2 2 2 0 Transmembrane 52 WBP-1 PF11669.8 KFO98916.1 - 0.089 13.4 19.9 0.52 11.0 19.9 2.2 1 1 0 1 1 1 0 WW domain-binding protein 1 Bax1-I PF01027.20 KFO98917.1 - 3.4e-39 134.8 13.5 5e-39 134.3 13.5 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 ABC2_membrane_5 PF13346.6 KFO98917.1 - 1.9 8.0 7.5 1e+02 2.4 6.6 2.7 1 1 0 1 1 1 0 ABC-2 family transporter protein LapA_dom PF06305.11 KFO98918.1 - 0.0039 17.0 0.1 0.0069 16.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain DUF3021 PF11457.8 KFO98918.1 - 0.026 14.9 0.3 0.038 14.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) Insulin_TMD PF17870.1 KFO98918.1 - 0.044 13.9 0.4 0.083 13.0 0.4 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment PrgH PF09480.10 KFO98918.1 - 0.089 12.1 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) DUF5305 PF17231.2 KFO98918.1 - 0.1 12.0 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) HSF_DNA-bind PF00447.17 KFO98919.1 - 2.8e-26 91.9 1.3 4e-26 91.5 1.3 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding BOP1NT PF08145.12 KFO98920.1 - 1.4e-110 369.3 8.3 2.1e-110 368.8 8.3 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KFO98920.1 - 1.9e-25 88.6 7.4 2.8e-11 43.8 0.2 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO98920.1 - 6.2e-07 29.6 0.4 0.0013 19.0 0.0 3.9 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain SOTI PF17079.5 KFO98920.1 - 0.067 13.6 0.1 6.9 7.1 0.0 2.6 2 0 0 2 2 2 0 Male-specific protein scotti Ge1_WD40 PF16529.5 KFO98920.1 - 0.14 11.1 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cnd1 PF12717.7 KFO98921.1 - 6.6e-11 42.5 10.2 0.017 15.2 0.0 7.9 5 3 3 8 8 8 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFO98921.1 - 1.1e-09 37.7 1.2 1.3 9.4 0.0 9.6 9 0 0 9 9 9 1 HEAT repeat HEAT_2 PF13646.6 KFO98921.1 - 4.7e-09 36.5 0.5 1.7 9.1 0.0 7.2 6 1 0 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 KFO98921.1 - 2.2e-05 24.9 7.7 0.19 12.3 0.1 7.1 8 0 0 8 8 7 1 HEAT-like repeat MMS19_N PF14500.6 KFO98921.1 - 0.0014 18.3 1.3 1.5 8.4 0.1 4.6 3 1 1 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II RTP1_C1 PF10363.9 KFO98921.1 - 0.002 18.3 3.3 13 6.0 0.1 5.5 5 0 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 KFO98921.1 - 0.0027 18.3 0.0 3.8 8.2 0.0 4.3 2 2 1 3 3 3 1 Vacuolar 14 Fab1-binding region UME PF08064.13 KFO98921.1 - 0.0031 17.4 1.0 0.11 12.4 0.0 3.9 3 0 0 3 3 3 1 UME (NUC010) domain ParcG PF10274.9 KFO98921.1 - 0.024 14.8 2.1 1.1 9.4 0.0 4.3 4 0 0 4 4 4 0 Parkin co-regulated protein CbeA_antitoxin PF06154.11 KFO98921.1 - 0.054 14.1 0.0 1.1 9.9 0.0 3.0 3 0 0 3 3 2 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A RTP1_C2 PF10304.9 KFO98921.1 - 0.24 11.1 0.8 0.62 9.8 0.0 2.2 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 2 DUF4515 PF14988.6 KFO98922.1 - 5.1e-15 55.9 25.8 5.1e-15 55.9 25.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4515) ISG65-75 PF11727.8 KFO98922.1 - 0.019 14.2 18.4 0.2 10.8 6.1 2.1 1 1 1 2 2 2 0 Invariant surface glycoprotein DUF2205 PF10224.9 KFO98922.1 - 0.046 13.7 1.5 0.046 13.7 1.5 3.6 2 1 2 4 4 4 0 Short coiled-coil protein Filament PF00038.21 KFO98922.1 - 0.056 13.0 28.4 0.058 13.0 27.2 1.5 1 1 1 2 2 2 0 Intermediate filament protein FPP PF05911.11 KFO98922.1 - 0.075 11.2 27.1 0.12 10.5 27.1 1.3 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil Tropomyosin_1 PF12718.7 KFO98922.1 - 0.32 11.1 32.4 0.017 15.3 21.3 2.2 1 1 1 2 2 2 0 Tropomyosin like Baculo_PEP_C PF04513.12 KFO98922.1 - 0.4 10.7 9.6 0.42 10.7 5.1 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus PilJ PF13675.6 KFO98922.1 - 0.46 10.5 8.5 0.3 11.1 2.5 2.7 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF725 PF05267.12 KFO98922.1 - 0.5 10.4 13.9 0.074 13.0 5.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF725) MHB PF16525.5 KFO98922.1 - 0.72 10.1 12.6 4.2 7.7 1.4 3.9 2 1 2 4 4 4 0 Haemophore, haem-binding DUF1664 PF07889.12 KFO98922.1 - 1.2 9.1 17.1 0.19 11.8 3.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) GAS PF13851.6 KFO98922.1 - 3.1 7.1 35.6 0.16 11.3 21.2 2.2 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4618 PF15397.6 KFO98922.1 - 4 6.8 29.6 3.7 6.9 28.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) FapA PF03961.13 KFO98922.1 - 6.8 5.2 22.8 4.8 5.7 12.0 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A Pkinase PF00069.25 KFO98923.1 - 6.7e-61 205.9 0.0 8.6e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO98923.1 - 8.4e-28 97.4 0.0 1.1e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFO98923.1 - 0.0019 17.2 0.1 0.0032 16.5 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFO98923.1 - 0.0081 15.5 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFO98923.1 - 0.014 14.8 0.2 0.022 14.1 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAM83 PF07894.12 KFO98924.1 - 7.9e-101 337.2 0.0 2.6e-100 335.5 0.0 1.9 2 0 0 2 2 2 1 FAM83 A-H PLDc_2 PF13091.6 KFO98924.1 - 0.0012 18.7 0.2 0.0029 17.5 0.0 1.7 2 0 0 2 2 2 1 PLD-like domain SEO_C PF14577.6 KFO98924.1 - 0.095 12.1 0.7 0.19 11.2 0.7 1.4 1 0 0 1 1 1 0 Sieve element occlusion C-terminus LRR_8 PF13855.6 KFO98925.1 - 4.7e-33 112.7 48.1 4.1e-08 32.8 4.4 6.4 3 2 2 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFO98925.1 - 7.6e-29 99.3 49.6 7.5e-05 23.0 0.0 8.5 4 2 4 9 9 9 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFO98925.1 - 1.3e-07 31.3 21.5 9.7e-05 21.9 2.2 5.0 2 1 3 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.33 KFO98925.1 - 0.014 15.9 45.4 15 6.7 0.2 12.3 11 3 1 12 12 12 0 Leucine Rich Repeat H-kinase_dim PF02895.14 KFO98925.1 - 0.82 10.1 4.3 2.4 8.6 0.3 3.5 3 1 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain CSTF_C PF14304.6 KFO98925.1 - 1.4 8.6 10.7 6.8 6.4 0.1 5.0 5 0 0 5 5 5 0 Transcription termination and cleavage factor C-terminal RRM_1 PF00076.22 KFO98926.1 - 5.6e-44 147.8 0.1 1e-18 66.9 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFO98926.1 - 0.00068 19.7 2.4 0.48 10.6 0.0 3.5 4 1 0 4 4 4 2 RNA recognition motif OB_RNB PF08206.11 KFO98926.1 - 0.058 13.1 0.1 5.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain RRM_3 PF08777.11 KFO98926.1 - 0.097 12.7 0.0 8 6.6 0.0 2.8 2 0 0 2 2 2 0 RNA binding motif Pkinase PF00069.25 KFO98927.1 - 2.4e-20 73.0 0.5 1.5e-19 70.5 0.5 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO98927.1 - 3.9e-19 68.9 0.1 6.9e-19 68.1 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Plectin PF00681.20 KFO98928.1 - 7.3e-50 166.6 0.0 6.2e-21 74.0 0.0 4.9 4 1 1 5 5 5 4 Plectin repeat RVT_1 PF00078.27 KFO98931.1 - 0.029 13.9 0.0 0.085 12.4 0.0 1.8 3 0 0 3 3 3 0 Reverse transcriptase (RNA-dependent DNA polymerase) Homeobox_KN PF05920.11 KFO98932.1 - 2.6e-17 62.4 0.4 3.7e-17 61.9 0.4 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFO98932.1 - 1.7e-08 34.2 0.4 2e-08 33.9 0.4 1.1 1 0 0 1 1 1 1 Homeodomain MRP-S32 PF10210.9 KFO98932.1 - 0.0078 16.7 1.1 0.0084 16.6 1.1 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S32 Homez PF11569.8 KFO98932.1 - 0.036 13.5 0.0 0.091 12.2 0.0 1.7 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez RVT_1 PF00078.27 KFO98933.1 - 0.077 12.5 0.0 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Homeobox_KN PF05920.11 KFO98934.1 - 6.2e-16 58.0 0.4 1.7e-15 56.6 0.4 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFO98934.1 - 3e-07 30.2 1.7 4e-07 29.8 0.8 1.6 2 0 0 2 2 2 1 Homeodomain MRP-S32 PF10210.9 KFO98934.1 - 0.0018 18.8 1.9 0.002 18.6 0.4 1.8 2 0 0 2 2 2 1 Mitochondrial 28S ribosomal protein S32 FAM176 PF14851.6 KFO98934.1 - 0.046 13.4 6.4 0.73 9.5 0.5 2.3 2 0 0 2 2 2 0 FAM176 family BUD22 PF09073.10 KFO98934.1 - 0.42 9.9 10.9 0.61 9.4 10.9 1.2 1 0 0 1 1 1 0 BUD22 CNDH2_C PF16858.5 KFO98934.1 - 5.2 6.9 8.8 15 5.3 8.8 1.7 1 1 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Homeobox_KN PF05920.11 KFO98935.1 - 3.7e-17 61.9 0.4 5.5e-17 61.4 0.4 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFO98935.1 - 9.8e-09 34.9 2.3 1.2e-08 34.7 2.3 1.1 1 0 0 1 1 1 1 Homeodomain MRP-S32 PF10210.9 KFO98935.1 - 0.016 15.7 2.1 0.019 15.5 2.1 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 Cas_Cmr5 PF09701.10 KFO98935.1 - 0.052 13.8 0.1 0.056 13.7 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr5) Homez PF11569.8 KFO98935.1 - 0.055 13.0 0.1 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez zf-CHCC PF10276.9 KFO98937.1 - 2.2e-18 66.0 0.7 2.9e-18 65.6 0.7 1.2 1 0 0 1 1 1 1 Zinc-finger domain Acyltransferase PF01553.21 KFO98939.1 - 4.7e-17 61.9 0.0 8.3e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase EF-hand_8 PF13833.6 KFO98939.1 - 2e-06 27.6 5.7 5.7e-05 22.9 0.1 3.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KFO98939.1 - 4.2e-06 26.3 3.8 0.82 9.8 0.1 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 KFO98939.1 - 9.6e-05 22.8 5.3 0.017 15.6 5.3 3.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFO98939.1 - 0.0014 18.0 6.3 0.9 9.2 0.4 4.2 4 0 0 4 4 4 2 EF hand SNF PF00209.18 KFO98940.1 - 6.3e-178 592.7 28.8 8.1e-178 592.3 28.8 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 KFO98941.1 - 3.2e-177 590.4 28.1 4e-177 590.1 28.1 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF2614 PF11023.8 KFO98941.1 - 5.3 7.2 6.8 0.75 9.9 0.1 3.0 3 0 0 3 3 3 0 Zinc-ribbon containing domain AAA_23 PF13476.6 KFO98942.1 - 0.33 11.4 9.5 0.47 10.9 9.5 1.2 1 0 0 1 1 1 0 AAA domain PIN_3 PF13470.6 KFO98942.1 - 0.41 11.4 3.3 1.1 10.1 3.3 2.0 1 1 0 1 1 1 0 PIN domain Exonuc_VII_L PF02601.15 KFO98942.1 - 0.66 9.5 8.2 0.84 9.1 8.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAD_binding_2 PF00890.24 KFO98943.1 - 2.5e-126 422.2 2.4 3e-126 421.9 2.4 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KFO98943.1 - 1.9e-38 131.3 0.0 2.9e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KFO98943.1 - 8.4e-06 25.2 0.3 0.0022 17.3 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFO98943.1 - 1.4e-05 24.4 0.4 0.1 11.8 0.1 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 KFO98943.1 - 0.00019 20.7 3.5 0.066 12.3 2.2 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KFO98943.1 - 0.0042 16.4 0.1 0.0068 15.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFO98943.1 - 0.046 13.3 0.1 0.12 11.9 0.1 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KFO98943.1 - 0.15 10.8 1.0 0.82 8.3 0.1 2.5 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.6 KFO98943.1 - 0.57 9.4 1.6 3.4 6.8 0.5 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lyase_1 PF00206.20 KFO98944.1 - 3.9e-123 410.8 0.1 5.2e-123 410.4 0.1 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KFO98944.1 - 1.4e-27 95.8 0.1 7.4e-27 93.5 0.0 2.2 2 0 0 2 2 2 1 Fumarase C C-terminus DUF4288 PF14119.6 KFO98944.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) Snf7 PF03357.21 KFO98945.1 - 2.3e-51 173.8 20.7 2.7e-51 173.6 20.7 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 KFO98945.1 - 0.0025 18.2 3.4 0.0025 18.2 3.4 2.8 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 KFO98945.1 - 0.031 14.5 0.7 0.031 14.5 0.7 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Prefoldin_2 PF01920.20 KFO98945.1 - 0.069 13.1 21.8 0.6 10.1 0.8 3.5 2 1 1 3 3 3 0 Prefoldin subunit Alpha-E PF04168.12 KFO98945.1 - 0.083 12.7 1.3 0.12 12.1 0.9 1.5 1 1 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. Hydantoinase_B PF02538.14 KFO98945.1 - 0.2 10.1 1.5 0.22 9.9 1.5 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase BCDHK_Adom3 PF10436.9 KFO98945.1 - 0.22 11.3 2.9 0.31 10.9 2.9 1.2 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Endotoxin_N PF03945.14 KFO98945.1 - 1.4 8.6 6.5 2.8 7.6 6.5 1.5 1 1 0 1 1 1 0 delta endotoxin, N-terminal domain DUF848 PF05852.11 KFO98945.1 - 2 8.6 10.0 0.81 9.8 6.9 1.9 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) YlqD PF11068.8 KFO98945.1 - 2.5 8.5 18.1 8.8 6.7 5.0 2.2 1 1 1 2 2 2 0 YlqD protein GvpK PF05121.12 KFO98945.1 - 3.2 7.8 12.6 1.4 9.0 2.9 3.1 1 1 1 3 3 3 0 Gas vesicle protein K CorA PF01544.18 KFO98945.1 - 4.1 6.6 15.6 5.2 6.3 9.6 2.8 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein BAG PF02179.16 KFO98946.1 - 2.1e-08 34.5 2.3 5.1e-08 33.2 2.3 1.7 1 1 0 1 1 1 1 BAG domain ubiquitin PF00240.23 KFO98946.1 - 3.2e-08 33.2 0.1 3.2e-08 33.2 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin family PHTB1_C PF14728.6 KFO98946.1 - 0.00056 19.1 1.3 0.00068 18.8 1.3 1.1 1 0 0 1 1 1 1 PTHB1 C-terminus EzrA PF06160.12 KFO98946.1 - 0.0025 16.1 4.4 0.0033 15.7 4.4 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Ubiquitin_5 PF18037.1 KFO98946.1 - 0.0031 17.8 1.1 0.0083 16.5 0.0 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain SesA PF17107.5 KFO98946.1 - 0.008 16.4 2.6 0.014 15.6 2.6 1.4 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases YPEB PF14620.6 KFO98946.1 - 0.025 13.9 2.6 0.02 14.3 1.2 1.5 2 0 0 2 2 2 0 YpeB sporulation DASH_Duo1 PF08651.10 KFO98946.1 - 0.027 14.3 1.7 0.32 10.8 0.5 2.5 2 0 0 2 2 2 0 DASH complex subunit Duo1 PIN_8 PF18476.1 KFO98946.1 - 0.048 13.5 3.7 0.077 12.8 3.7 1.2 1 0 0 1 1 1 0 PIN like domain DUF2247 PF10004.9 KFO98946.1 - 0.053 13.3 1.1 0.069 12.9 1.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) MscS_porin PF12795.7 KFO98946.1 - 0.06 12.9 6.3 0.4 10.2 0.3 2.4 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain Sigma54_DBD PF04552.13 KFO98946.1 - 0.085 12.6 0.4 0.14 11.8 0.4 1.4 1 0 0 1 1 1 0 Sigma-54, DNA binding domain Ubiquitin_4 PF18036.1 KFO98946.1 - 0.098 12.7 0.4 0.67 10.0 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain Spectrin PF00435.21 KFO98946.1 - 0.12 12.8 6.5 0.74 10.3 3.9 2.6 3 0 0 3 3 3 0 Spectrin repeat Sec34 PF04136.15 KFO98946.1 - 0.26 11.2 3.3 0.61 10.0 2.5 1.9 1 1 0 1 1 1 0 Sec34-like family TRPM_tetra PF16519.5 KFO98946.1 - 0.3 11.2 3.3 2.8 8.1 0.9 3.3 2 1 2 4 4 4 0 Tetramerisation domain of TRPM FapA PF03961.13 KFO98946.1 - 0.39 9.3 8.9 0.73 8.4 8.9 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A GrpE PF01025.19 KFO98946.1 - 0.59 9.8 8.8 1.1 9.0 8.4 1.6 1 1 0 1 1 1 0 GrpE Seryl_tRNA_N PF02403.22 KFO98946.1 - 0.97 9.7 11.2 1.2 9.4 8.0 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4140 PF13600.6 KFO98946.1 - 1.9 8.9 5.3 2.9 8.4 1.6 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DASH_Dad2 PF08654.10 KFO98946.1 - 2.1 8.8 7.8 0.34 11.3 0.9 2.6 2 1 1 3 3 2 0 DASH complex subunit Dad2 Prefoldin PF02996.17 KFO98946.1 - 2.1 8.3 9.9 0.87 9.5 1.4 2.7 2 1 1 3 3 3 0 Prefoldin subunit WXG100 PF06013.12 KFO98946.1 - 2.6 8.3 6.0 21 5.5 0.1 2.9 3 1 1 4 4 3 0 Proteins of 100 residues with WXG DUF1033 PF06279.11 KFO98947.1 - 0.00074 19.7 0.4 0.0015 18.7 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1033) KH_1 PF00013.29 KFO98948.1 - 6.9e-56 186.0 13.4 3.7e-19 68.3 0.4 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KFO98948.1 - 8.1e-17 60.8 6.2 7e-06 25.8 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KFO98948.1 - 3.7e-09 36.3 2.9 0.005 16.7 0.4 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KFO98948.1 - 2.8e-07 30.5 6.3 0.075 13.1 0.1 3.4 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 KFO98948.1 - 6.1e-05 23.0 0.0 0.012 15.6 0.0 3.1 3 0 0 3 3 3 1 KH-like RNA-binding domain DUF370 PF04025.12 KFO98948.1 - 0.0075 16.4 1.0 0.34 11.1 0.1 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF370) Y_phosphatase PF00102.27 KFO98949.1 - 1.7e-79 266.7 1.4 3.9e-79 265.5 1.4 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FERM_C PF09380.10 KFO98949.1 - 5.3e-25 87.6 1.4 1.8e-24 85.9 1.4 2.0 1 0 0 1 1 1 1 FERM C-terminal PH-like domain PDZ PF00595.24 KFO98949.1 - 6.7e-21 74.4 0.1 1.9e-20 73.0 0.0 1.8 2 0 0 2 2 2 1 PDZ domain FERM_M PF00373.18 KFO98949.1 - 9.2e-20 71.2 0.1 2.4e-19 69.9 0.1 1.8 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 KFO98949.1 - 2.1e-16 59.6 0.0 4.2e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 FERM N-terminal domain PDZ_6 PF17820.1 KFO98949.1 - 8e-07 28.8 0.0 1.5e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain DSPc PF00782.20 KFO98949.1 - 3.9e-05 23.5 0.1 9.2e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFO98949.1 - 0.00036 20.6 0.0 0.00066 19.7 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFO98949.1 - 0.0016 18.6 0.1 0.0034 17.5 0.1 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Trm112p PF03966.16 KFO98949.1 - 0.018 15.6 0.0 2.4 8.8 0.0 3.2 1 1 0 1 1 1 0 Trm112p-like protein PDZ_2 PF13180.6 KFO98949.1 - 0.023 15.0 0.0 0.07 13.5 0.0 1.8 1 0 0 1 1 1 0 PDZ domain DOMON PF03351.17 KFO98951.1 - 1.2e-23 83.7 0.1 1.5e-23 83.3 0.1 1.1 1 0 0 1 1 1 1 DOMON domain AI-2E_transport PF01594.16 KFO98952.1 - 2.2e-11 43.5 29.7 3.6e-10 39.5 18.4 4.1 4 1 0 4 4 4 2 AI-2E family transporter Tubulin_2 PF13809.6 KFO98952.1 - 0.42 9.7 1.1 0.58 9.3 0.1 1.7 2 0 0 2 2 2 0 Tubulin like Vma12 PF11712.8 KFO98952.1 - 8.7 6.4 6.3 2.2 8.4 2.4 2.0 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase YL1_C PF08265.11 KFO98953.1 - 3.7e-12 45.8 0.9 7.1e-12 44.9 0.1 2.0 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Glycos_transf_2 PF00535.26 KFO98954.1 - 1.4e-38 132.4 0.0 2.2e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFO98954.1 - 1e-29 103.3 3.0 1.7e-29 102.6 3.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 KFO98954.1 - 1.7e-08 34.6 0.0 3e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KFO98954.1 - 1.3e-05 24.7 0.1 2.7e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.6 KFO98954.1 - 6.8e-05 23.5 0.2 0.043 14.5 0.1 2.8 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Glyco_tranf_2_2 PF10111.9 KFO98954.1 - 0.0006 19.4 0.0 0.0017 17.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Decorin_bind PF02352.15 KFO98954.1 - 0.18 12.1 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 Decorin binding protein DUF4674 PF15719.5 KFO98955.1 - 2.7e-68 229.8 17.5 3e-68 229.6 17.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4674) DUF695 PF05117.12 KFO98955.1 - 0.045 13.9 0.0 0.063 13.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF695) zf-U1 PF06220.12 KFO98955.1 - 0.68 9.8 3.1 1.7 8.5 0.2 2.8 3 0 0 3 3 3 0 U1 zinc finger CREPT PF16566.5 KFO98956.1 - 3e-58 196.2 1.2 3e-58 196.2 1.2 1.5 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour CTD_bind PF04818.13 KFO98956.1 - 1e-22 80.7 0.3 4.6e-22 78.6 0.0 2.2 2 1 0 2 2 2 1 RNA polymerase II-binding domain. DUF1631 PF07793.11 KFO98956.1 - 0.0093 14.5 0.1 0.0093 14.5 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1631) PhoU PF01895.19 KFO98956.1 - 0.011 16.2 2.1 0.17 12.4 0.7 2.3 2 0 0 2 2 2 0 PhoU domain DIRP PF06584.13 KFO98956.1 - 0.035 14.3 0.9 0.1 12.8 0.3 2.0 2 0 0 2 2 2 0 DIRP Com_YlbF PF06133.11 KFO98956.1 - 0.055 14.1 1.4 0.28 11.8 0.3 2.4 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA FH2 PF02181.23 KFO98957.1 - 9.6e-93 311.2 7.6 9.6e-93 311.2 7.6 1.8 2 0 0 2 2 2 1 Formin Homology 2 Domain V-set PF07686.17 KFO98958.1 - 1.2e-10 41.5 0.2 2.6e-10 40.5 0.2 1.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFO98958.1 - 9e-09 35.8 0.1 3.1e-08 34.1 0.1 1.9 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFO98958.1 - 1.1e-08 35.0 1.2 1.2e-07 31.7 1.2 2.2 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFO98958.1 - 2.4e-08 34.0 0.4 7.4e-08 32.5 0.4 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFO98958.1 - 0.002 18.4 0.1 1.8 8.9 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Phage_base_V PF04717.12 KFO98958.1 - 0.12 12.3 0.2 0.34 10.9 0.1 1.7 1 1 0 1 1 1 0 Type VI secretion system, phage-baseplate injector Cobl PF09469.10 KFO98959.1 - 1.3e-43 147.2 1.7 6.8e-43 144.9 0.4 2.4 2 0 0 2 2 2 1 Cordon-bleu ubiquitin-like domain RBD PF02196.15 KFO98959.1 - 4e-08 33.2 1.1 1.1e-05 25.4 0.1 2.6 2 0 0 2 2 2 2 Raf-like Ras-binding domain TUG-UBL1 PF11470.8 KFO98959.1 - 0.0006 20.0 0.2 0.038 14.2 0.1 2.5 2 0 0 2 2 2 1 TUG ubiquitin-like domain Rad60-SLD PF11976.8 KFO98959.1 - 0.0022 17.8 0.0 0.0055 16.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like WH2 PF02205.20 KFO98960.1 - 1.3e-15 56.7 4.6 3.3e-05 23.6 0.1 3.6 3 0 0 3 3 3 3 WH2 motif BPS PF08947.10 KFO98961.1 - 2.1e-28 97.9 0.7 3.9e-28 97.0 0.7 1.5 1 0 0 1 1 1 1 BPS (Between PH and SH2) SH2 PF00017.24 KFO98961.1 - 2.4e-15 56.4 0.0 5.2e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 SH2 domain RA PF00788.23 KFO98961.1 - 7e-11 42.6 0.3 1.8e-10 41.3 0.1 1.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain PH PF00169.29 KFO98961.1 - 1.2e-10 41.8 0.1 2.8e-10 40.7 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KFO98961.1 - 0.044 14.2 0.0 0.13 12.6 0.0 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain Pyridoxal_deC PF00282.19 KFO98962.1 - 2.2e-165 549.9 0.0 2.7e-165 549.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KFO98962.1 - 0.00011 21.7 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KFO98962.1 - 0.0057 15.9 0.1 0.021 14.0 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II AAA PF00004.29 KFO98963.1 - 9e-38 129.7 0.0 1.6e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFO98963.1 - 4.9e-08 32.6 0.0 1.6e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 AAA+ lid domain Vps4_C PF09336.10 KFO98963.1 - 1.6e-07 31.2 0.0 5.4e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 KFO98963.1 - 5.5e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KFO98963.1 - 0.0026 17.7 0.1 0.014 15.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFO98963.1 - 0.0028 17.8 0.0 0.0056 16.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KFO98963.1 - 0.0073 16.7 2.9 0.38 11.1 0.2 2.9 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KFO98963.1 - 0.012 15.9 1.3 0.5 10.6 0.3 2.7 1 1 1 2 2 2 0 AAA domain TIP49 PF06068.13 KFO98963.1 - 0.033 13.4 0.1 0.072 12.3 0.0 1.4 1 1 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 KFO98963.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KFO98963.1 - 0.14 11.5 0.1 0.33 10.3 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI zf-H2C2_2 PF13465.6 KFO98964.1 - 6.5e-19 67.4 34.1 1.6e-06 28.3 0.2 6.3 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFO98964.1 - 5e-16 58.2 44.9 1e-05 25.7 0.4 6.6 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO98964.1 - 2.8e-10 40.1 41.8 0.0002 21.9 0.4 6.8 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFO98964.1 - 0.0057 16.4 0.2 0.0057 16.4 0.2 4.4 4 0 0 4 4 4 1 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KFO98964.1 - 0.0062 16.3 0.1 0.0062 16.3 0.1 5.1 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFO98964.1 - 0.012 15.8 25.4 0.44 10.9 0.0 5.7 5 1 1 6 6 6 0 Zinc-finger double-stranded RNA-binding Zn_ribbon_recom PF13408.6 KFO98964.1 - 0.062 13.8 1.1 0.062 13.8 1.1 4.1 4 1 0 4 4 3 0 Recombinase zinc beta ribbon domain GAGA PF09237.11 KFO98964.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.5 2 1 1 3 3 3 0 GAGA factor zf-met PF12874.7 KFO98964.1 - 0.25 11.8 0.1 0.25 11.8 0.1 5.8 6 0 0 6 6 6 0 Zinc-finger of C2H2 type RNA_POL_M_15KD PF02150.16 KFO98964.1 - 0.49 10.3 11.4 6.4 6.7 0.0 5.3 6 0 0 6 6 6 0 RNA polymerases M/15 Kd subunit DUF4764 PF15961.5 KFO98964.1 - 7.4 5.1 10.2 0.73 8.5 5.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4764) Sp38 PF07354.12 KFO98966.1 - 6.8e-47 159.2 4.7 1.1e-46 158.5 4.7 1.3 1 0 0 1 1 1 1 Zona-pellucida-binding protein (Sp38) DUF2701 PF10857.8 KFO98966.1 - 0.044 13.8 0.2 0.22 11.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2701) VWC PF00093.18 KFO98967.1 - 5e-12 45.9 50.5 1.6e-09 38.0 16.3 3.1 3 0 0 3 3 3 3 von Willebrand factor type C domain Pacifastin_I PF05375.13 KFO98967.1 - 5.8e-05 22.7 4.3 5.8e-05 22.7 4.3 4.3 4 1 0 4 4 4 2 Pacifastin inhibitor (LCMII) zf-CCCH_2 PF14608.6 KFO98967.1 - 0.015 15.8 3.4 0.17 12.4 0.9 4.8 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger Yae1_N PF09811.9 KFO98968.1 - 7.6e-18 63.9 63.3 1.8e+04 -28.1 63.3 6.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal DUF1987 PF09345.10 KFO98969.1 - 0.45 10.2 5.3 0.54 9.9 0.2 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF1987) DUF4363 PF14276.6 KFO98971.1 - 0.05 13.7 0.5 0.15 12.2 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) PNP_UDP_1 PF01048.20 KFO98972.1 - 2.4e-22 79.4 0.0 2.8e-22 79.1 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF5524 PF17662.1 KFO98973.1 - 1.6e-68 231.2 5.7 1.8e-68 231.1 5.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5524) Med10 PF09748.9 KFO98974.1 - 2.2e-37 127.7 0.3 2.5e-37 127.5 0.3 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Sigma70_r1_1 PF03979.14 KFO98974.1 - 0.025 14.6 1.5 5.6 7.1 0.0 2.3 2 1 0 2 2 2 0 Sigma-70 factor, region 1.1 DUF3198 PF11433.8 KFO98974.1 - 0.037 13.9 0.0 0.091 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3198) IL12 PF03039.14 KFO98974.1 - 0.048 13.0 0.0 0.055 12.8 0.0 1.1 1 0 0 1 1 1 0 Interleukin-12 alpha subunit UQ_con PF00179.26 KFO98975.1 - 5.5e-06 26.1 0.0 7.8e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFO98975.1 - 0.069 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Methyltr_RsmB-F PF01189.17 KFO98976.1 - 6.4e-40 136.9 0.0 6.5e-36 123.9 0.0 2.5 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KFO98976.1 - 0.0027 17.8 0.0 0.0054 16.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Steroid_dh PF02544.16 KFO98977.1 - 8.6e-43 145.9 0.5 9.8e-43 145.7 0.5 1.0 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KFO98977.1 - 4.2e-06 26.4 0.1 4.6e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Guanylate_cyc PF00211.20 KFO98978.1 - 5.9e-122 404.1 1.3 1.3e-64 217.2 0.1 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF1053 PF06327.14 KFO98978.1 - 1.4e-36 125.1 0.6 2.6e-36 124.3 0.6 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) AC_N PF16214.5 KFO98978.1 - 5.8e-27 94.9 12.1 5.8e-27 94.9 12.1 2.1 3 0 0 3 3 3 1 Adenylyl cyclase N-terminal extracellular and transmembrane region HNOBA PF07701.14 KFO98978.1 - 0.019 14.4 1.2 0.079 12.4 0.4 2.1 2 0 0 2 2 2 0 Heme NO binding associated DUF349 PF03993.12 KFO98978.1 - 1 9.7 5.8 2.1 8.7 0.3 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) FAST_2 PF08368.12 KFO98979.1 - 3.4e-23 82.2 0.1 1.2e-22 80.4 0.1 2.1 1 0 0 1 1 1 1 FAST kinase-like protein, subdomain 2 FAST_1 PF06743.15 KFO98979.1 - 1.7e-20 72.7 2.4 1.7e-20 72.7 2.4 3.8 3 1 0 4 4 4 1 FAST kinase-like protein, subdomain 1 RAP PF08373.10 KFO98979.1 - 5.9e-14 51.9 0.1 1.4e-13 50.7 0.1 1.7 1 0 0 1 1 1 1 RAP domain CARMIL_C PF16000.5 KFO98979.1 - 0.19 11.3 0.1 0.31 10.6 0.1 1.2 1 0 0 1 1 1 0 CARMIL C-terminus FAD_binding_1 PF00667.20 KFO98980.1 - 2.5e-45 154.8 0.0 3.9e-45 154.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFO98980.1 - 1.4e-30 106.4 0.0 2.7e-30 105.4 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KFO98980.1 - 4.5e-12 46.6 0.0 1.2e-11 45.2 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KFO98980.1 - 4.4e-06 27.0 0.0 8.8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.7 KFO98980.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain Pentapeptide_4 PF13599.6 KFO98981.1 - 0.0067 16.6 0.0 0.5 10.6 0.0 2.1 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Lamprin PF06403.11 KFO98981.1 - 0.11 12.4 0.0 0.46 10.4 0.0 1.8 1 1 0 1 1 1 0 Lamprin Sema PF01403.19 KFO98982.1 - 3.8e-104 348.9 0.2 5.6e-104 348.3 0.2 1.2 1 0 0 1 1 1 1 Sema domain TSP_1 PF00090.19 KFO98982.1 - 1.4e-45 153.3 96.1 8.2e-12 45.2 5.2 7.7 7 1 0 7 7 7 5 Thrombospondin type 1 domain Methyltransf_23 PF13489.6 KFO98984.1 - 2.2e-05 24.4 0.0 2.8e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFO98984.1 - 0.001 19.8 0.0 0.0017 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 KFO98984.1 - 0.023 15.0 0.0 0.04 14.3 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase PrmA PF06325.13 KFO98984.1 - 0.035 13.5 0.0 0.04 13.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KFO98984.1 - 0.043 13.6 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KFO98984.1 - 0.082 13.6 0.0 0.13 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 KFO98984.1 - 0.093 12.7 0.0 0.29 11.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 KFO98984.1 - 0.14 11.7 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase small domain N6_N4_Mtase PF01555.18 KFO98984.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 DNA methylase Cpn60_TCP1 PF00118.24 KFO98985.1 - 8.1e-161 536.0 4.7 9.8e-161 535.7 4.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pkinase PF00069.25 KFO98986.1 - 1.4e-44 152.5 0.0 1.7e-44 152.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO98986.1 - 4.7e-22 78.5 0.0 5.3e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFO98986.1 - 8e-06 25.4 0.0 2.2e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KFO98986.1 - 0.013 15.1 0.0 1.3 8.6 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DLH PF01738.18 KFO98987.1 - 6.5e-43 146.8 0.0 7.4e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KFO98987.1 - 1.8e-08 34.5 0.0 2.5e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KFO98987.1 - 0.00013 21.5 0.2 0.0012 18.3 0.0 2.1 1 1 1 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.13 KFO98987.1 - 0.0003 20.5 0.2 0.0014 18.3 0.2 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 KFO98987.1 - 0.0034 16.7 0.0 0.0098 15.2 0.0 1.7 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFO98987.1 - 0.0091 15.7 0.1 0.64 9.6 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF1935 PF09149.10 KFO98987.1 - 0.011 16.1 0.0 0.018 15.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) Abhydrolase_3 PF07859.13 KFO98987.1 - 0.19 11.6 0.0 0.4 10.5 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 KFO98988.1 - 7.3e-36 123.7 0.0 8.3e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KFO98988.1 - 5.1e-09 36.2 0.0 6.9e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KFO98988.1 - 3.3e-08 33.5 0.0 7.5e-05 22.5 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFO98988.1 - 1.1e-06 28.3 0.1 0.025 14.1 0.0 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KFO98988.1 - 4.3e-05 23.5 0.0 0.045 13.6 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KFO98988.1 - 0.00018 20.5 0.0 0.00026 20.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KFO98988.1 - 0.00024 20.5 0.1 0.12 11.7 0.1 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFO98988.1 - 0.00038 21.1 0.0 0.00046 20.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 KFO98988.1 - 0.0017 18.0 0.1 0.026 14.2 0.1 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF915 PF06028.11 KFO98988.1 - 0.0032 16.8 0.0 0.0062 15.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase PF07224.11 KFO98988.1 - 0.0067 15.5 0.0 0.0089 15.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase BAAT_C PF08840.11 KFO98988.1 - 0.08 12.9 0.3 1.1 9.1 0.1 2.1 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Cutinase PF01083.22 KFO98988.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.5 1 1 0 1 1 1 0 Cutinase RINGv PF12906.7 KFO98989.1 - 8.6e-15 54.6 8.6 2e-14 53.5 8.6 1.7 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KFO98989.1 - 1.7 9.0 15.7 0.058 13.7 9.3 2.0 2 0 0 2 2 2 0 Ring finger domain DUF2373 PF10180.9 KFO98990.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.5 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) TadF PF16964.5 KFO98991.1 - 3.8 7.2 7.1 23 4.7 7.1 2.1 1 1 0 1 1 1 0 Putative tight adherence pilin protein F Ank_5 PF13857.6 KFO98992.1 - 4.5e-16 58.7 2.0 8.3e-07 29.2 0.3 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFO98992.1 - 5.2e-15 55.8 0.3 1.1e-14 54.8 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFO98992.1 - 6.4e-14 52.1 1.0 4.6e-07 30.2 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFO98992.1 - 8.7e-08 31.9 0.4 0.12 13.0 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KFO98992.1 - 1.1e-06 28.8 1.6 0.00043 20.6 0.0 3.2 4 0 0 4 4 4 2 Ankyrin repeat DUF4602 PF15375.6 KFO98992.1 - 0.024 15.0 4.5 0.052 13.9 4.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4602) DAP PF15228.6 KFO98993.1 - 2.5e-29 102.4 7.0 2.7e-29 102.2 7.0 1.0 1 0 0 1 1 1 1 Death-associated protein Arm PF00514.23 KFO98994.1 - 8.9e-49 162.1 8.5 2.4e-09 36.9 0.1 8.8 9 0 0 9 9 9 6 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KFO98994.1 - 2.7e-08 34.1 0.9 0.0064 16.9 0.0 3.3 2 2 0 2 2 2 2 HEAT repeats HEAT PF02985.22 KFO98994.1 - 9.1e-05 22.4 4.8 0.33 11.3 0.0 5.5 6 0 0 6 6 6 1 HEAT repeat Adaptin_N PF01602.20 KFO98994.1 - 0.0051 15.4 0.0 0.37 9.3 0.0 2.2 2 0 0 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.6 KFO98994.1 - 0.0088 16.5 3.4 28 5.3 0.1 4.9 4 1 1 5 5 5 1 HEAT-like repeat Atx10homo_assoc PF09759.9 KFO98994.1 - 0.0093 16.0 0.8 0.52 10.4 0.0 3.4 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Ribosomal_L28e PF01778.17 KFO98996.1 - 1.4e-35 122.5 0.2 1.4e-35 122.5 0.2 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 KFO98996.1 - 5.9e-31 107.0 16.3 5.9e-31 107.0 16.3 2.6 2 1 1 3 3 3 1 Mak16 protein C-terminal region BUD22 PF09073.10 KFO98996.1 - 0.0023 17.3 15.4 0.0027 17.1 15.4 1.1 1 0 0 1 1 1 1 BUD22 YqfQ PF14181.6 KFO98996.1 - 0.39 10.9 7.9 0.69 10.1 7.9 1.4 1 0 0 1 1 1 0 YqfQ-like protein CDC45 PF02724.14 KFO98996.1 - 4.7 5.4 17.2 6.3 5.0 17.2 1.3 1 0 0 1 1 1 0 CDC45-like protein PHP PF02811.19 KFO98997.1 - 0.16 12.2 0.0 0.17 12.2 0.0 1.1 1 0 0 1 1 1 0 PHP domain zf-RING_11 PF17123.5 KFO98998.1 - 1.6e-09 37.3 0.4 4e-09 36.1 0.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KFO98998.1 - 1.1e-05 25.6 0.5 2.7e-05 24.4 0.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFO98998.1 - 0.0031 17.3 0.5 0.0076 16.1 0.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFO98998.1 - 0.0047 16.9 0.4 0.0047 16.9 0.4 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFO98998.1 - 0.013 15.3 0.3 0.013 15.3 0.3 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFO98998.1 - 0.026 14.5 0.4 0.052 13.5 0.4 1.6 1 0 0 1 1 1 0 zinc-RING finger domain LapA_dom PF06305.11 KFO98998.1 - 0.19 11.6 0.1 0.3 10.9 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DSPc PF00782.20 KFO98999.1 - 5.4e-30 103.9 0.0 6.5e-30 103.7 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFO98999.1 - 0.00048 19.8 0.0 0.00067 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase UPA PF17217.3 KFO99000.1 - 1.3e-60 203.4 2.4 1.8e-60 202.9 0.4 2.1 2 0 0 2 2 2 1 UPA domain ZU5 PF00791.20 KFO99000.1 - 8.1e-31 106.3 0.0 2e-30 105.0 0.0 1.7 1 0 0 1 1 1 1 ZU5 domain Death PF00531.22 KFO99000.1 - 2.5e-13 50.0 0.1 4.8e-13 49.1 0.1 1.5 1 0 0 1 1 1 1 Death domain I-set PF07679.16 KFO99000.1 - 2e-12 47.0 0.0 1.8e-11 43.9 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO99000.1 - 2.4e-12 47.3 0.0 5.1e-10 39.8 0.0 2.8 2 0 0 2 2 2 1 Immunoglobulin domain TSP_1 PF00090.19 KFO99000.1 - 4.4e-10 39.6 24.7 4e-07 30.2 10.6 3.0 2 0 0 2 2 2 2 Thrombospondin type 1 domain ig PF00047.25 KFO99000.1 - 1.2e-08 35.0 0.0 9.5e-08 32.1 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFO99000.1 - 8.2e-08 32.5 0.6 3.3e-07 30.5 0.0 2.4 3 0 0 3 3 3 1 Immunoglobulin domain Ig_6 PF18452.1 KFO99000.1 - 0.018 14.6 0.0 0.045 13.3 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KFO99000.1 - 0.021 15.0 0.1 0.21 11.8 0.0 2.6 2 1 0 2 2 2 0 Immunoglobulin V-set domain Band_7 PF01145.25 KFO99002.1 - 2e-07 31.2 0.6 2e-07 31.2 0.6 1.8 1 1 1 2 2 2 1 SPFH domain / Band 7 family DUF4346 PF14251.6 KFO99002.1 - 0.022 14.8 1.4 0.048 13.7 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4346) RapA_C PF12137.8 KFO99002.1 - 0.06 12.4 5.8 0.081 11.9 5.8 1.2 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal Ala_racemase_N PF01168.20 KFO99003.1 - 5.9e-20 71.9 0.0 7.7e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain CobT PF06213.12 KFO99004.1 - 6e-06 25.9 0.2 8.9e-06 25.3 0.2 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT TFIIB PF00382.19 KFO99004.1 - 0.00032 20.7 0.0 1.4 9.0 0.0 2.7 2 1 0 2 2 2 2 Transcription factor TFIIB repeat RXT2_N PF08595.11 KFO99004.1 - 0.0025 17.8 4.6 0.0049 16.9 4.6 1.4 1 0 0 1 1 1 1 RXT2-like, N-terminal DUF2052 PF09747.9 KFO99004.1 - 0.0031 17.7 5.9 0.005 17.0 5.9 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) DUF2828 PF11443.8 KFO99004.1 - 0.0037 15.4 2.5 0.0049 15.0 2.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) CPSF100_C PF13299.6 KFO99004.1 - 0.015 15.4 4.4 0.027 14.6 4.4 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RNA_pol_Rpc4 PF05132.14 KFO99004.1 - 0.02 15.3 3.0 0.035 14.6 3.0 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 KFO99004.1 - 0.067 13.0 10.6 0.11 12.3 10.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 KFO99004.1 - 0.078 13.1 0.3 0.12 12.5 0.3 1.3 1 0 0 1 1 1 0 DDHD domain Vfa1 PF08432.10 KFO99004.1 - 0.1 12.9 16.0 0.18 12.1 16.0 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NESP55 PF06390.12 KFO99004.1 - 0.11 12.0 11.1 0.19 11.3 11.1 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) DUF4770 PF15994.5 KFO99004.1 - 0.13 12.5 6.4 0.042 14.1 3.7 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4770) RB_B PF01857.20 KFO99004.1 - 0.15 12.1 0.1 0.15 12.1 0.1 2.7 2 1 1 3 3 2 0 Retinoblastoma-associated protein B domain CDC45 PF02724.14 KFO99004.1 - 0.19 10.0 8.7 0.27 9.5 8.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.8 KFO99004.1 - 0.2 10.4 7.8 0.28 9.9 7.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Gti1_Pac2 PF09729.9 KFO99004.1 - 0.26 11.4 5.8 0.44 10.6 5.8 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family NPAT_C PF15712.5 KFO99004.1 - 0.26 9.9 7.0 0.35 9.4 7.0 1.1 1 0 0 1 1 1 0 NPAT C terminus Eapp_C PF10238.9 KFO99004.1 - 0.3 11.2 6.5 0.71 9.9 6.5 1.6 1 0 0 1 1 1 0 E2F-associated phosphoprotein Endonuc-BglII PF09195.11 KFO99004.1 - 0.32 10.8 3.9 0.65 9.8 3.9 1.4 1 0 0 1 1 1 0 Restriction endonuclease BglII CLN3 PF02487.17 KFO99004.1 - 0.5 9.3 1.7 0.77 8.7 1.7 1.2 1 0 0 1 1 1 0 CLN3 protein SpoIIP PF07454.11 KFO99004.1 - 0.56 9.6 9.3 0.87 9.0 9.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Trypan_PARP PF05887.11 KFO99004.1 - 0.58 10.1 8.2 1.1 9.3 8.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TFB6 PF17110.5 KFO99004.1 - 0.59 9.9 3.6 1.1 9.0 3.6 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Atrophin-1 PF03154.15 KFO99004.1 - 0.68 8.1 21.1 0.97 7.6 21.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family Presenilin PF01080.17 KFO99004.1 - 0.74 8.5 4.9 1.1 7.9 4.9 1.2 1 0 0 1 1 1 0 Presenilin Peptidase_S49_N PF08496.10 KFO99004.1 - 0.93 9.5 14.7 1.8 8.6 14.7 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Connexin PF00029.19 KFO99004.1 - 1 9.1 9.8 1.8 8.3 9.8 1.4 1 0 0 1 1 1 0 Connexin Sec62 PF03839.16 KFO99004.1 - 1.1 8.7 10.3 1.9 7.9 10.3 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 AAA_11 PF13086.6 KFO99004.1 - 1.4 8.6 8.4 2.9 7.6 8.4 1.4 1 0 0 1 1 1 0 AAA domain DUF1682 PF07946.14 KFO99004.1 - 1.5 7.9 17.8 2.2 7.4 17.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) NPR3 PF03666.13 KFO99004.1 - 2.1 7.0 8.1 3.5 6.3 8.1 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MAP17 PF15807.5 KFO99004.1 - 2.6 8.3 9.9 4.8 7.4 9.9 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Phage_Gp23 PF10669.9 KFO99004.1 - 2.6 8.4 16.3 5.4 7.4 16.3 1.5 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Afi1 PF07792.12 KFO99004.1 - 2.9 8.4 8.4 6.5 7.2 8.4 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking U79_P34 PF03064.16 KFO99004.1 - 3.3 7.0 13.9 5.4 6.3 13.9 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 30K_MP_C_Ter PF11330.8 KFO99004.1 - 3.3 7.0 9.8 4.8 6.4 9.8 1.2 1 0 0 1 1 1 0 C-Terminal of 30K viral movement proteins V_ATPase_I PF01496.19 KFO99004.1 - 4.5 5.1 7.6 6.7 4.5 7.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NARP1 PF12569.8 KFO99004.1 - 5.6 5.8 15.5 9.2 5.0 15.5 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Zip PF02535.22 KFO99004.1 - 6.5 5.9 5.4 11 5.1 5.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter AIF_C PF14721.6 KFO99004.1 - 7.8 6.9 8.2 15 6.0 8.2 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Nucleoplasmin PF03066.15 KFO99005.1 - 1.9e-08 34.7 0.1 1.9e-08 34.7 0.1 1.6 2 0 0 2 2 2 1 Nucleoplasmin/nucleophosmin domain eIF_4EBP PF05456.11 KFO99006.1 - 1.7e-18 66.7 0.0 1.7e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) TGF_beta PF00019.20 KFO99007.1 - 9e-30 103.7 1.0 1.6e-29 102.9 1.0 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFO99007.1 - 0.0013 18.5 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 TGF-beta propeptide SPRY PF00622.28 KFO99008.1 - 4.5e-12 46.1 0.3 0.00012 22.2 0.0 2.4 2 0 0 2 2 2 2 SPRY domain EPTP PF03736.17 KFO99009.1 - 1.5e-69 229.8 11.1 2.2e-10 40.3 0.1 7.3 7 0 0 7 7 7 7 EPTP domain LRR_8 PF13855.6 KFO99009.1 - 1.4e-22 79.2 12.5 4.7e-14 51.9 6.0 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_5 PF13306.6 KFO99009.1 - 5.8e-09 36.0 0.1 1.2e-08 34.9 0.1 1.5 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFO99009.1 - 1.6e-06 28.4 11.5 0.0013 19.1 1.1 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFO99009.1 - 2.9e-05 23.7 0.4 5e-05 22.9 0.4 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRRCT PF01463.24 KFO99009.1 - 0.00011 22.4 0.1 0.0014 19.0 0.1 2.8 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain TPKR_C2 PF16920.5 KFO99009.1 - 0.11 12.7 1.1 3.1 8.0 0.1 3.1 2 0 0 2 2 2 0 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_1 PF00560.33 KFO99009.1 - 0.16 12.6 9.5 7.9 7.5 0.5 4.8 4 0 0 4 4 4 0 Leucine Rich Repeat 7tm_1 PF00001.21 KFO99010.1 - 3.2e-80 269.2 5.6 3.7e-80 269.0 5.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFO99010.1 - 1.2e-18 67.5 4.5 1.6e-18 67.1 4.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFO99010.1 - 1.2e-09 38.1 8.8 2.3e-09 37.3 8.8 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFO99010.1 - 2.3e-07 30.5 0.2 3.8e-07 29.7 0.2 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFO99010.1 - 0.00082 19.2 7.6 0.0027 17.5 4.0 2.4 3 0 0 3 3 3 1 Olfactory receptor Piwi PF02171.17 KFO99011.1 - 1.9e-52 178.4 0.5 1.6e-31 109.7 0.1 2.2 1 1 1 2 2 2 2 Piwi domain Zip PF02535.22 KFO99012.1 - 2.9e-68 230.5 5.8 5.3e-68 229.7 4.4 1.9 2 0 0 2 2 2 1 ZIP Zinc transporter SH3_2 PF07653.17 KFO99013.1 - 4.3e-15 55.1 0.0 4.6e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFO99013.1 - 7.4e-14 51.1 0.0 9.3e-14 50.8 0.0 1.0 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFO99013.1 - 8.7e-14 51.1 0.0 1e-13 50.9 0.0 1.0 1 0 0 1 1 1 1 Variant SH3 domain DUF3446 PF11928.8 KFO99015.1 - 1.1e-06 28.8 0.4 2e-06 28.0 0.4 1.4 1 0 0 1 1 1 1 Early growth response N-terminal domain MACPF PF01823.19 KFO99016.1 - 3.8e-07 30.4 0.1 1.4e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 MAC/Perforin domain RhoGAP-FF1 PF16512.5 KFO99016.1 - 0.098 13.3 0.1 0.81 10.4 0.1 2.4 2 0 0 2 2 2 0 p190-A and -B Rho GAPs FF domain Cnn_1N PF07989.11 KFO99017.1 - 2.6e-23 82.0 10.7 2.6e-23 82.0 10.7 15.0 14 3 3 17 17 17 2 Centrosomin N-terminal motif 1 HALZ PF02183.18 KFO99017.1 - 0.023 14.9 0.1 0.023 14.9 0.1 12.7 16 0 0 16 16 16 0 Homeobox associated leucine zipper Laminin_EGF PF00053.24 KFO99019.1 - 1.1e-38 131.1 103.6 3.5e-09 36.7 18.2 5.3 5 0 0 5 5 5 5 Laminin EGF domain TMEM154 PF15102.6 KFO99019.1 - 0.0024 17.8 0.3 0.0042 17.0 0.3 1.4 1 0 0 1 1 1 1 TMEM154 protein family Ephrin_rec_like PF07699.13 KFO99019.1 - 0.015 15.0 7.0 0.015 15.0 7.0 7.3 4 3 3 7 7 7 0 Putative ephrin-receptor like cEGF PF12662.7 KFO99019.1 - 0.02 14.8 2.6 0.02 14.8 2.6 9.2 7 2 1 8 8 8 0 Complement Clr-like EGF-like Prominin PF05478.11 KFO99019.1 - 0.037 12.0 0.0 0.037 12.0 0.0 1.9 2 0 0 2 2 2 0 Prominin Stevor PF17410.2 KFO99019.1 - 0.051 13.1 0.2 0.08 12.5 0.2 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF3262 PF11660.8 KFO99019.1 - 0.072 13.5 0.5 0.14 12.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) ApoM PF11032.8 KFO99020.1 - 8.4e-08 32.1 0.0 1.1e-07 31.7 0.0 1.0 1 0 0 1 1 1 1 ApoM domain Lipocalin PF00061.23 KFO99020.1 - 2.9e-07 30.8 0.1 4.6e-07 30.1 0.1 1.3 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Flagellar_rod PF05149.12 KFO99020.1 - 0.072 12.5 0.1 0.14 11.6 0.1 1.5 2 0 0 2 2 2 0 Paraflagellar rod protein Mito_carr PF00153.27 KFO99021.1 - 3.6e-74 244.8 2.2 5.5e-25 87.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KFO99021.1 - 3.1e-14 53.2 2.1 2.4e-10 40.7 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFO99021.1 - 1.2e-13 49.6 2.7 0.0014 18.1 0.2 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KFO99021.1 - 4e-12 45.0 2.8 0.00023 20.8 0.1 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 KFO99021.1 - 3.7e-08 33.1 1.3 0.0051 16.6 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFO99021.1 - 9e-05 21.8 1.9 0.23 11.0 0.0 3.2 3 1 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 KFO99021.1 - 0.0014 19.0 1.1 0.0029 17.9 1.1 1.5 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KFO99021.1 - 0.0031 17.3 1.4 2.5 8.0 0.0 3.5 2 1 1 3 3 3 2 EF hand EF-hand_4 PF12763.7 KFO99021.1 - 0.086 12.8 2.7 0.92 9.5 0.2 2.5 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF1002 PF06207.11 KFO99021.1 - 0.19 11.3 0.2 0.3 10.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) NT-C2 PF10358.9 KFO99022.1 - 6.6e-30 103.8 0.0 1.5e-29 102.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DPM2 PF07297.12 KFO99023.1 - 6e-21 74.5 1.1 6.6e-21 74.4 1.1 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) TMEM154 PF15102.6 KFO99023.1 - 0.017 15.0 0.5 0.02 14.8 0.5 1.1 1 0 0 1 1 1 0 TMEM154 protein family Spem1 PF15670.5 KFO99023.1 - 0.04 13.5 0.1 0.04 13.5 0.1 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 LAX PF15681.5 KFO99023.1 - 0.063 12.1 1.0 0.073 11.9 1.0 1.0 1 0 0 1 1 1 0 Lymphocyte activation family X S1FA PF04689.13 KFO99023.1 - 0.08 13.1 0.3 0.098 12.8 0.3 1.2 1 0 0 1 1 1 0 DNA binding protein S1FA Glyco_transf_29 PF00777.18 KFO99024.1 - 4.9e-29 101.5 0.0 6.8e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Pkinase PF00069.25 KFO99025.1 - 5.2e-71 239.1 0.0 6.2e-71 238.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO99025.1 - 3e-33 115.2 0.0 3.8e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFO99025.1 - 1.8e-07 30.5 0.1 2.4e-07 30.1 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFO99025.1 - 0.00034 20.0 0.1 0.18 11.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KFO99025.1 - 0.039 12.7 0.0 0.077 11.8 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase RIO1 PF01163.22 KFO99025.1 - 0.6 9.7 3.7 0.49 10.0 0.9 2.1 2 1 0 2 2 2 0 RIO1 family SH2 PF00017.24 KFO99026.1 - 2e-14 53.4 0.1 4e-14 52.5 0.1 1.6 1 0 0 1 1 1 1 SH2 domain RasGEF PF00617.19 KFO99026.1 - 8.9e-12 45.6 0.0 1.9e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain Helicase_C_4 PF13871.6 KFO99026.1 - 0.013 15.2 0.2 3.6 7.2 0.1 2.3 2 0 0 2 2 2 0 C-terminal domain on Strawberry notch homologue Torsin PF06309.11 KFO99027.1 - 9.4e-39 132.4 0.0 1.8e-38 131.5 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_2 PF07724.14 KFO99027.1 - 0.00037 20.7 0.0 0.0048 17.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KFO99027.1 - 0.011 16.2 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 KFO99027.1 - 0.012 15.7 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KFO99027.1 - 0.019 15.2 0.1 2.2 8.6 0.1 2.3 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KFO99027.1 - 0.057 12.6 0.0 0.092 11.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.18 KFO99027.1 - 0.093 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Pept_tRNA_hydro PF01195.19 KFO99028.1 - 5.4e-35 120.9 0.0 6.1e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Glyco_transf_25 PF01755.17 KFO99029.1 - 1.4e-28 100.1 0.0 8.8e-27 94.3 0.0 2.6 2 1 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_tranf_2_4 PF13704.6 KFO99029.1 - 9.9e-11 42.0 0.1 2.3e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Anp1 PF03452.14 KFO99029.1 - 4.9e-06 26.2 0.0 8.2e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 KFO99029.1 - 0.03 14.1 0.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 MT-A70 PF05063.14 KFO99029.1 - 0.084 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 MT-A70 Urm1 PF09138.11 KFO99030.1 - 1e-37 128.4 0.0 1.1e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KFO99030.1 - 0.00099 19.7 0.0 0.0012 19.5 0.0 1.1 1 0 0 1 1 1 1 ThiS family AMP-binding PF00501.28 KFO99031.1 - 3.7e-70 236.7 0.0 4.3e-70 236.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFO99031.1 - 0.0046 17.9 0.0 0.0088 17.0 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Coq4 PF05019.13 KFO99032.1 - 3.3e-96 320.9 0.0 3.8e-96 320.7 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Rnk_N PF14760.6 KFO99032.1 - 0.065 13.7 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 Rnk N-terminus TruB_N PF01509.18 KFO99033.1 - 1.8e-19 70.6 0.0 2.5e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KFO99033.1 - 0.00068 19.7 0.3 0.0067 16.5 0.0 2.4 2 1 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain Swi5 PF07061.11 KFO99034.1 - 1.7e-23 82.5 1.0 2e-23 82.3 1.0 1.0 1 0 0 1 1 1 1 Swi5 APG6_N PF17675.1 KFO99034.1 - 0.017 15.7 1.0 0.02 15.4 1.0 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region ZapB PF06005.12 KFO99034.1 - 0.033 14.6 2.6 0.052 14.0 2.6 1.4 1 1 0 1 1 1 0 Cell division protein ZapB DUF5338 PF17273.2 KFO99034.1 - 0.07 13.2 0.0 0.097 12.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5338) LINES_C PF14695.6 KFO99034.1 - 0.25 10.8 0.8 22 4.6 0.1 2.5 3 0 0 3 3 3 0 Lines C-terminus GOLGA2L5 PF15070.6 KFO99035.1 - 1.4e-234 780.5 87.4 1.4e-234 780.5 87.4 2.2 2 0 0 2 2 2 1 Putative golgin subfamily A member 2-like protein 5 CALCOCO1 PF07888.11 KFO99035.1 - 0.0031 16.4 14.1 0.0031 16.4 14.1 5.9 2 2 5 7 7 7 3 Calcium binding and coiled-coil domain (CALCOCO1) like GIT_CC PF16559.5 KFO99035.1 - 0.22 11.4 0.0 0.22 11.4 0.0 11.3 9 2 3 12 12 12 0 GIT coiled-coil Rho guanine nucleotide exchange factor DinB_2 PF12867.7 KFO99035.1 - 3.6 8.1 18.1 0.91 10.0 0.2 5.6 2 2 3 5 5 5 0 DinB superfamily Dynamin_M PF01031.20 KFO99036.1 - 8.2e-111 369.8 4.8 8.2e-111 369.8 4.8 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KFO99036.1 - 1.5e-41 142.3 0.0 5.6e-41 140.4 0.0 2.1 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 KFO99036.1 - 8.6e-29 99.5 2.6 2.6e-28 98.0 2.6 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain PH PF00169.29 KFO99036.1 - 3.5e-12 46.8 0.9 7.1e-12 45.8 0.9 1.5 1 0 0 1 1 1 1 PH domain Glyco_transf_36 PF06165.11 KFO99036.1 - 0.095 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 36 Ldh_1_N PF00056.23 KFO99036.1 - 0.099 12.7 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain PH_11 PF15413.6 KFO99036.1 - 0.18 12.3 3.6 0.77 10.2 1.8 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain zf-C2H2_jaz PF12171.8 KFO99037.1 - 8.5e-05 22.7 0.5 8.5e-05 22.7 0.5 4.8 4 1 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFO99037.1 - 0.0015 18.8 29.3 0.0025 18.1 7.2 4.5 4 0 0 4 4 4 3 Zinc-finger of C2H2 type Myc_N PF01056.18 KFO99037.1 - 0.0047 16.9 2.4 0.0047 16.9 2.4 1.7 2 0 0 2 2 2 1 Myc amino-terminal region AKAP95 PF04988.12 KFO99037.1 - 0.0082 16.4 14.2 0.0088 16.3 10.2 2.1 2 0 0 2 2 2 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.7 KFO99037.1 - 0.037 14.4 0.9 0.037 14.4 0.9 4.1 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFO99037.1 - 0.055 14.3 1.1 0.055 14.3 1.1 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger THAP PF05485.12 KFO99037.1 - 1.6 9.7 10.7 0.51 11.3 7.1 2.1 2 0 0 2 2 2 0 THAP domain zf-C2H2 PF00096.26 KFO99037.1 - 2.4 8.8 31.0 0.057 13.9 2.6 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type UPF0184 PF03670.13 KFO99038.1 - 2.7e-24 85.3 3.3 3.1e-24 85.2 3.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0184) EzrA PF06160.12 KFO99038.1 - 0.0022 16.2 0.9 0.0023 16.2 0.9 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA NYD-SP28 PF14772.6 KFO99038.1 - 0.0043 17.1 2.8 0.0057 16.7 2.8 1.1 1 0 0 1 1 1 1 Sperm tail PhaP_Bmeg PF09602.10 KFO99038.1 - 0.012 15.6 1.0 0.012 15.5 1.0 1.1 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) SKA1 PF07160.12 KFO99038.1 - 0.025 14.4 0.3 0.025 14.4 0.3 1.0 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Med29 PF11568.8 KFO99038.1 - 0.039 14.2 1.4 0.046 13.9 1.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 29 GST_N_3 PF13417.6 KFO99039.1 - 3.5e-12 46.5 0.7 2.4e-11 43.8 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 KFO99039.1 - 4.7e-10 39.5 0.1 1.1e-09 38.4 0.1 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.6 KFO99039.1 - 6.6e-09 35.9 0.1 2.3e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFO99039.1 - 1.1e-06 28.5 1.5 1.3e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KFO99039.1 - 0.0001 23.0 0.0 0.00025 21.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C PF00043.25 KFO99039.1 - 0.00042 20.5 0.1 0.00082 19.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFO99039.1 - 0.00066 20.0 0.0 0.0015 18.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFO99039.1 - 0.0023 18.1 0.1 0.0045 17.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF641 PF04859.12 KFO99040.1 - 0.00072 19.9 9.3 0.00072 19.9 9.3 9.5 1 1 7 10 10 10 3 Plant protein of unknown function (DUF641) ADIP PF11559.8 KFO99040.1 - 0.0052 16.9 9.0 0.0052 16.9 9.0 9.4 2 2 5 9 9 9 5 Afadin- and alpha -actinin-Binding Par3_HAL_N_term PF12053.8 KFO99040.1 - 0.084 13.1 2.2 2.9 8.2 0.3 3.8 2 0 0 2 2 2 0 N-terminal of Par3 and HAL proteins GLE1 PF07817.13 KFO99041.1 - 1.9e-84 282.8 0.1 1.9e-84 282.8 0.1 2.0 2 0 0 2 2 2 1 GLE1-like protein Phosphatase PF15698.5 KFO99041.1 - 0.027 13.6 0.1 0.087 11.9 0.0 1.8 2 0 0 2 2 2 0 Phosphatase Exonuc_VII_L PF02601.15 KFO99041.1 - 0.39 10.2 29.1 0.12 12.0 6.7 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit NAP PF00956.18 KFO99042.1 - 1.3e-37 129.5 14.4 9.1e-34 116.9 5.3 3.1 2 1 1 3 3 3 2 Nucleosome assembly protein (NAP) Phage_Mu_Gam PF07352.12 KFO99042.1 - 0.0032 17.4 2.6 0.0069 16.3 2.6 1.6 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein Mst1_SARAH PF11629.8 KFO99042.1 - 0.064 13.4 0.8 0.17 12.0 0.8 1.7 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 ZapB PF06005.12 KFO99042.1 - 2 8.9 9.9 0.12 12.9 4.4 1.8 2 0 0 2 2 2 0 Cell division protein ZapB Nore1-SARAH PF16517.5 KFO99042.1 - 3.7 7.5 8.6 0.13 12.2 1.3 2.5 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Pkinase PF00069.25 KFO99043.1 - 1.3e-62 211.5 0.0 2.3e-62 210.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HR1 PF02185.16 KFO99043.1 - 1.7e-46 156.2 26.6 3.4e-16 59.1 3.9 3.3 3 0 0 3 3 3 3 Hr1 repeat Pkinase_Tyr PF07714.17 KFO99043.1 - 5.4e-35 120.9 0.0 1e-34 120.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KFO99043.1 - 1.1e-08 35.6 1.3 3e-08 34.2 1.3 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Uds1 PF15456.6 KFO99043.1 - 7.1e-07 29.4 18.1 0.00093 19.4 0.8 3.4 3 0 0 3 3 3 3 Up-regulated During Septation Kinase-like PF14531.6 KFO99043.1 - 9.2e-06 25.2 0.0 2.2e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Kinase-like PL48 PF15903.5 KFO99043.1 - 0.0021 17.1 1.5 0.78 8.6 0.1 2.4 2 0 0 2 2 2 2 Filopodia upregulated, FAM65 DUF2564 PF10819.8 KFO99043.1 - 1.1 9.7 4.4 1.9 8.9 1.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) Cortex-I_coil PF09304.10 KFO99043.1 - 8.2 6.7 13.7 4.5 7.5 1.0 2.7 2 0 0 2 2 2 0 Cortexillin I, coiled coil DHHC PF01529.20 KFO99044.1 - 3e-30 105.0 13.4 7.8e-30 103.7 12.7 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase Baculo_11_kDa PF06143.11 KFO99044.1 - 0.04 13.5 1.6 0.33 10.6 1.0 2.2 2 0 0 2 2 2 0 Baculovirus 11 kDa family Sigma_reg_N PF13800.6 KFO99044.1 - 0.22 11.8 1.2 45 4.4 2.9 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Arm PF00514.23 KFO99045.1 - 1.2e-09 37.8 0.2 1.7 8.8 0.0 6.9 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KFO99045.1 - 0.004 17.6 0.0 0.029 14.9 0.0 2.6 3 0 0 3 3 3 1 HEAT-like repeat zf-CCCH_6 PF18585.1 KFO99045.1 - 0.0093 15.8 0.2 2.5 8.1 0.0 3.9 3 0 0 3 3 3 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 DUF3361 PF11841.8 KFO99045.1 - 0.013 15.5 1.6 2.3 8.1 0.8 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3361) SWC7 PF17330.2 KFO99045.1 - 0.032 14.3 0.7 0.14 12.2 0.1 2.4 2 0 0 2 2 2 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 LRR_4 PF12799.7 KFO99045.1 - 0.056 13.9 10.5 3.5 8.2 0.2 5.2 2 2 5 7 7 7 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFO99045.1 - 0.092 12.5 9.3 3.1 7.6 0.3 4.1 4 0 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.33 KFO99045.1 - 0.18 12.4 5.5 39 5.3 0.1 5.7 5 0 0 5 5 5 0 Leucine Rich Repeat RabGAP-TBC PF00566.18 KFO99046.1 - 1.1e-37 129.8 4.3 9.9e-35 120.1 0.5 2.7 2 1 0 2 2 2 2 Rab-GTPase-TBC domain TFIID_20kDa PF03847.13 KFO99046.1 - 0.032 14.7 0.6 0.084 13.4 0.1 2.0 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A PhyH PF05721.13 KFO99047.1 - 4e-63 213.5 0.0 4.9e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) BAR PF03114.18 KFO99049.1 - 8.3e-66 222.0 2.2 1.6e-65 221.1 2.2 1.5 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 KFO99049.1 - 5.1e-11 42.2 0.1 1.1e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFO99049.1 - 1.7e-06 27.6 0.0 3.2e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFO99049.1 - 1.9e-06 27.4 0.0 3.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.9 KFO99049.1 - 8.6e-06 25.1 0.4 2.1e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 KFO99049.1 - 0.00012 21.8 0.8 0.26 11.0 1.2 2.2 1 1 1 2 2 2 2 BAR domain of APPL family Spore_III_AB PF09548.10 KFO99049.1 - 0.11 12.6 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Miga PF10265.9 KFO99050.1 - 7e-174 579.8 0.9 7.1e-127 424.6 0.1 2.0 2 0 0 2 2 2 2 Mitoguardin VasL PF12486.8 KFO99050.1 - 0.02 14.7 1.8 0.54 10.1 0.8 2.4 2 0 0 2 2 2 0 Type VI secretion system, EvfB, or VasL 7TM_GPCR_Sri PF10327.9 KFO99050.1 - 0.13 11.5 0.1 0.22 10.7 0.1 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri DUF3824 PF12868.7 KFO99050.1 - 0.16 12.6 0.2 0.36 11.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) PAP2 PF01569.21 KFO99051.1 - 1.3e-17 63.8 5.8 2.5e-17 62.9 5.8 1.4 1 0 0 1 1 1 1 PAP2 superfamily UbiA PF01040.18 KFO99051.1 - 0.0046 16.3 8.5 0.0046 16.3 8.5 2.0 2 0 0 2 2 2 1 UbiA prenyltransferase family WTF PF03303.13 KFO99051.1 - 0.053 13.3 0.5 0.068 12.9 0.5 1.2 1 0 0 1 1 1 0 WTF protein Phage_holin_3_1 PF05106.12 KFO99051.1 - 0.069 13.6 0.4 0.14 12.6 0.4 1.5 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) DUF212 PF02681.14 KFO99051.1 - 0.07 13.3 0.7 1.4 9.1 0.1 2.3 1 1 1 2 2 2 0 Divergent PAP2 family PSI_PsaJ PF01701.18 KFO99051.1 - 0.24 12.0 5.7 3.3 8.3 0.1 3.2 3 0 0 3 3 3 0 Photosystem I reaction centre subunit IX / PsaJ Carn_acyltransf PF00755.20 KFO99052.1 - 1.6e-203 677.6 0.0 1.8e-203 677.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase PTPA PF03095.15 KFO99053.1 - 1.8e-121 405.2 0.0 2.1e-121 405.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Methyltransf_PK PF05891.12 KFO99054.1 - 8.6e-93 309.8 0.0 9.9e-93 309.7 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KFO99054.1 - 5.6e-13 49.4 0.0 1.6e-12 47.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFO99054.1 - 7e-11 42.6 0.0 1.2e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFO99054.1 - 2.5e-09 37.8 0.0 4.4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KFO99054.1 - 5.2e-06 25.9 0.0 1.1e-05 24.9 0.0 1.4 1 1 1 2 2 2 1 O-methyltransferase domain Methyltransf_31 PF13847.6 KFO99054.1 - 3.8e-05 23.5 0.0 5.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFO99054.1 - 0.00011 21.6 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KFO99054.1 - 0.022 14.3 0.0 0.038 13.6 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain DREV PF05219.12 KFO99054.1 - 0.093 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_29 PF03141.16 KFO99054.1 - 0.16 10.4 0.0 0.23 9.9 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ank_4 PF13637.6 KFO99055.1 - 5e-24 84.4 0.6 1.4e-05 25.5 0.0 6.5 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 KFO99055.1 - 2.5e-16 59.3 2.1 7.5e-07 29.3 0.0 5.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KFO99055.1 - 3e-15 56.1 2.0 4.4e-07 30.1 0.0 5.2 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFO99055.1 - 7.1e-15 55.4 0.0 7.6e-07 29.6 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFO99055.1 - 2.9e-14 51.8 0.6 2.6e-06 27.3 0.0 6.5 6 0 0 6 6 6 2 Ankyrin repeat SOCS_box PF07525.16 KFO99055.1 - 1.4e-12 47.7 2.2 1.4e-12 47.7 2.2 2.2 2 0 0 2 2 2 1 SOCS box N_methyl PF07963.12 KFO99055.1 - 0.19 11.4 0.1 0.33 10.6 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic N-terminal methylation motif Homeodomain PF00046.29 KFO99056.1 - 2.9e-23 81.5 6.9 5.7e-23 80.5 6.9 1.5 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 KFO99056.1 - 3.7e-08 32.9 0.1 9.1e-08 31.7 0.1 1.7 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 KFO99056.1 - 0.00029 20.7 0.1 0.00029 20.7 0.1 1.8 2 0 0 2 2 2 1 Homeobox KN domain MAPEG PF01124.18 KFO99057.1 - 6e-24 84.4 0.4 6.9e-24 84.2 0.4 1.0 1 0 0 1 1 1 1 MAPEG family Acyl_transf_3 PF01757.22 KFO99057.1 - 0.0032 16.6 0.4 0.0039 16.3 0.4 1.2 1 0 0 1 1 1 1 Acyltransferase family Torsin PF06309.11 KFO99058.1 - 2.9e-43 147.0 0.1 5.6e-43 146.1 0.1 1.5 1 0 0 1 1 1 1 Torsin AAA PF00004.29 KFO99058.1 - 1.8e-05 25.2 0.0 3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 KFO99058.1 - 0.0034 17.5 0.0 0.0058 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Viral_helicase1 PF01443.18 KFO99058.1 - 0.0042 16.9 0.0 0.0065 16.2 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KFO99058.1 - 0.011 16.0 0.0 0.92 9.8 0.0 2.2 1 1 1 2 2 2 0 AAA domain Torsin PF06309.11 KFO99059.1 - 5.1e-53 178.5 0.5 8.9e-53 177.7 0.5 1.4 1 0 0 1 1 1 1 Torsin AAA PF00004.29 KFO99059.1 - 0.0071 16.8 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KFO99059.1 - 0.053 13.3 0.1 0.094 12.4 0.0 1.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_5 PF07728.14 KFO99059.1 - 0.075 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFO99059.1 - 0.095 12.8 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFO99059.1 - 0.097 12.9 0.1 10 6.4 0.0 2.4 1 1 1 2 2 2 0 AAA domain Hep_59 PF07052.11 KFO99060.1 - 2.2e-29 102.3 5.7 2.2e-29 102.3 5.7 1.9 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 DHOR PF06537.11 KFO99060.1 - 0.1 11.2 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Di-haem oxidoreductase, putative peroxidase UCH PF00443.29 KFO99061.1 - 1.5e-61 208.2 0.0 7.3e-61 205.9 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KFO99061.1 - 5.8e-27 94.2 1.9 1e-15 58.1 0.0 2.9 3 0 0 3 3 3 2 DUSP domain UCH_1 PF13423.6 KFO99061.1 - 6.4e-19 68.7 0.2 4.7e-16 59.3 0.0 4.4 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFO99061.1 - 3.4e-16 59.3 5.0 3.4e-16 59.3 5.0 2.9 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein FCH PF00611.23 KFO99062.1 - 2e-18 66.4 2.2 2e-18 66.4 2.2 3.1 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 KFO99062.1 - 7e-10 38.6 0.2 1.6e-09 37.5 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFO99062.1 - 1.5e-09 37.3 0.1 3.5e-09 36.1 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFO99062.1 - 4.2e-06 26.3 0.1 9.7e-06 25.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFO99062.1 - 0.00013 22.1 0.2 0.00029 21.0 0.2 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain HR1 PF02185.16 KFO99062.1 - 0.00018 21.6 0.5 0.00018 21.6 0.5 2.9 4 1 0 4 4 4 1 Hr1 repeat Lzipper-MIP1 PF14389.6 KFO99062.1 - 0.0004 20.6 0.7 0.0014 18.9 0.7 1.9 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 Laminin_II PF06009.12 KFO99062.1 - 0.0057 16.7 7.6 0.24 11.4 0.5 3.0 2 1 0 2 2 2 2 Laminin Domain II SH3_16 PF18348.1 KFO99062.1 - 0.13 12.1 0.2 0.31 10.9 0.1 1.8 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain Spectrin PF00435.21 KFO99062.1 - 0.29 11.7 21.3 0.12 12.9 1.9 4.1 2 1 1 3 3 3 0 Spectrin repeat DUF4239 PF14023.6 KFO99062.1 - 3.8 7.2 4.9 30 4.3 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) DUF1664 PF07889.12 KFO99062.1 - 4.8 7.2 14.5 2.5 8.1 1.5 3.6 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Lung_7-TM_R PF06814.13 KFO99063.1 - 2.3e-96 322.5 8.2 2.9e-96 322.2 8.2 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor PIRT PF15099.6 KFO99063.1 - 0.048 13.2 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family EF-hand_7 PF13499.6 KFO99064.1 - 2.7e-25 88.6 3.8 2.5e-18 66.3 0.3 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KFO99064.1 - 5.4e-23 78.8 5.4 2.7e-07 29.7 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KFO99064.1 - 2.1e-22 77.1 3.8 8.5e-06 25.3 0.1 4.7 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 KFO99064.1 - 2.5e-16 58.3 4.4 8.4e-05 21.9 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KFO99064.1 - 6.4e-13 48.3 4.4 0.00019 21.2 0.3 3.6 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFO99064.1 - 3e-05 24.3 0.6 0.041 14.2 0.2 3.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFO99064.1 - 0.00071 19.5 1.8 0.6 10.1 0.1 3.0 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFO99064.1 - 0.0094 16.3 0.1 0.44 10.9 0.0 3.0 2 1 1 3 3 3 1 EF-hand domain Caleosin PF05042.13 KFO99064.1 - 0.011 15.7 1.5 8.5 6.3 0.0 3.1 1 1 1 3 3 3 0 Caleosin related protein EF-hand_3 PF09069.11 KFO99064.1 - 0.011 16.1 0.0 0.037 14.5 0.0 1.7 2 0 0 2 2 2 0 EF-hand DUF1707 PF08044.11 KFO99064.1 - 0.099 12.7 0.1 7.9 6.6 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1707) S10_plectin PF03501.15 KFO99064.1 - 0.18 11.9 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain G2F PF07474.12 KFO99065.1 - 2.1e-39 135.2 0.0 3e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 G2F domain Ig_3 PF13927.6 KFO99065.1 - 9.6e-17 61.4 0.0 1.4e-14 54.4 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFO99065.1 - 3.9e-16 58.9 0.0 1.3e-12 47.6 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFO99065.1 - 4.5e-11 42.9 0.0 1.5e-09 38.0 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 KFO99065.1 - 1.1e-09 38.4 0.0 3.1e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain EGF_CA PF07645.15 KFO99065.1 - 4e-08 33.3 2.9 4e-08 33.3 2.9 2.2 3 0 0 3 3 2 1 Calcium-binding EGF domain cEGF PF12662.7 KFO99065.1 - 1.4e-07 31.3 3.3 0.004 17.0 1.2 2.6 2 0 0 2 2 2 2 Complement Clr-like EGF-like V-set PF07686.17 KFO99065.1 - 1.5e-06 28.4 0.0 0.011 15.9 0.0 3.6 3 1 1 4 4 3 1 Immunoglobulin V-set domain EGF PF00008.27 KFO99065.1 - 5.8e-05 23.3 8.8 5.8e-05 23.3 8.8 2.2 2 0 0 2 2 2 1 EGF-like domain Ig_6 PF18452.1 KFO99065.1 - 0.00069 19.1 0.2 0.16 11.6 0.0 2.9 3 0 0 3 3 3 1 Immunoglobulin domain FXa_inhibition PF14670.6 KFO99065.1 - 0.0012 19.1 7.7 0.0012 19.1 7.7 2.4 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site hEGF PF12661.7 KFO99065.1 - 0.01 16.4 5.1 0.01 16.4 5.1 2.8 3 0 0 3 3 2 0 Human growth factor-like EGF Izumo-Ig PF16706.5 KFO99065.1 - 0.033 14.2 0.0 0.31 11.1 0.0 2.5 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain FlgD_ig PF13860.6 KFO99065.1 - 0.16 11.9 0.1 0.35 10.8 0.1 1.5 1 0 0 1 1 1 0 FlgD Ig-like domain EGF_3 PF12947.7 KFO99065.1 - 0.59 10.4 5.5 1.6 9.0 5.5 1.8 1 0 0 1 1 1 0 EGF domain Arginosuc_synth PF00764.19 KFO99066.1 - 8e-154 512.6 0.0 1.6e-153 511.6 0.0 1.4 1 1 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KFO99066.1 - 4.8e-05 22.9 0.0 7.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KFO99066.1 - 0.0034 16.2 0.0 0.0061 15.4 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase KH_1 PF00013.29 KFO99067.1 - 1.2e-69 230.0 17.2 3.1e-19 68.6 0.3 4.2 4 0 0 4 4 4 4 KH domain KH_2 PF07650.17 KFO99067.1 - 4.8e-22 77.6 8.9 1.3e-05 24.9 0.0 4.4 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 KFO99067.1 - 1.8e-12 47.0 8.4 0.025 14.4 0.1 4.3 4 0 0 4 4 4 4 KH domain DUF1897 PF09005.10 KFO99067.1 - 0.00061 19.2 8.9 0.0014 18.0 8.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1897) KH_5 PF13184.6 KFO99067.1 - 0.0042 17.1 10.3 10 6.3 0.1 4.4 4 0 0 4 4 4 3 NusA-like KH domain CBM_3 PF00942.18 KFO99068.1 - 0.0038 17.6 0.2 0.0053 17.2 0.2 1.2 1 0 0 1 1 1 1 Cellulose binding domain zf-H2C2_2 PF13465.6 KFO99069.1 - 8.7e-12 44.9 6.3 1.7e-05 25.0 0.6 2.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFO99069.1 - 6.8e-06 26.2 2.9 6.8e-06 26.2 2.9 2.3 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO99069.1 - 1e-05 25.9 2.1 1e-05 25.9 2.1 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO99069.1 - 0.0038 17.5 0.1 0.0054 17.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFO99069.1 - 0.0048 17.2 0.4 0.0091 16.4 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFO99069.1 - 0.01 15.6 1.4 0.01 15.6 1.4 2.9 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-BED PF02892.15 KFO99069.1 - 0.017 15.1 0.7 0.019 15.0 0.7 1.2 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_2 PF12756.7 KFO99069.1 - 0.023 15.0 0.1 0.024 15.0 0.1 1.1 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf_C2H2_6 PF18450.1 KFO99069.1 - 0.031 14.0 0.8 0.047 13.4 0.8 1.3 1 0 0 1 1 1 0 Zinc Finger domain DUF629 PF04780.12 KFO99069.1 - 0.035 12.7 0.1 0.035 12.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Pkinase_Tyr PF07714.17 KFO99070.1 - 6e-99 330.5 0.0 8.5e-99 330.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO99070.1 - 5.1e-48 163.7 0.0 8.5e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain F_actin_bind PF08919.10 KFO99070.1 - 6e-30 103.6 0.2 1.3e-29 102.5 0.2 1.6 1 0 0 1 1 1 1 F-actin binding SH2 PF00017.24 KFO99070.1 - 1.1e-23 83.2 0.2 2.6e-23 81.9 0.2 1.7 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFO99070.1 - 1.6e-12 46.9 0.0 2.8e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFO99070.1 - 1.2e-08 34.7 0.0 2.2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFO99070.1 - 1.7e-07 30.8 0.0 3.4e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFO99070.1 - 6e-05 23.3 0.2 0.00016 21.8 0.2 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain Haspin_kinase PF12330.8 KFO99070.1 - 0.0011 18.1 0.1 0.002 17.1 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain SH3_6 PF12913.7 KFO99070.1 - 0.15 11.7 0.0 0.38 10.3 0.0 1.7 1 0 0 1 1 1 0 SH3 domain (SH3b1 type) Fibrinogen_C PF00147.18 KFO99071.1 - 6e-78 261.6 4.9 8e-78 261.2 4.9 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Snapin_Pallidin PF14712.6 KFO99071.1 - 0.06 13.8 4.8 0.13 12.7 0.7 2.3 2 0 0 2 2 2 0 Snapin/Pallidin COLFI PF01410.18 KFO99071.1 - 0.076 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Fibrillar collagen C-terminal domain CENP-F_leu_zip PF10473.9 KFO99071.1 - 0.078 13.0 0.8 0.13 12.3 0.8 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KFO99071.1 - 0.1 12.8 1.8 0.16 12.2 1.8 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) CFC PF09443.10 KFO99071.1 - 0.2 11.5 1.8 0.4 10.6 1.8 1.5 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) Laminin_EGF PF00053.24 KFO99072.1 - 9.3e-81 265.8 221.4 8.7e-12 45.0 15.9 12.1 12 0 0 12 12 12 11 Laminin EGF domain Laminin_N PF00055.17 KFO99072.1 - 5.7e-74 248.6 0.0 5.7e-74 248.6 0.0 3.5 4 0 0 4 4 4 1 Laminin N-terminal (Domain VI) Laminin_B PF00052.18 KFO99072.1 - 3.3e-27 95.0 0.1 7e-27 94.0 0.1 1.6 1 0 0 1 1 1 1 Laminin B (Domain IV) APG17 PF04108.12 KFO99072.1 - 2 7.4 10.9 1.4 8.0 5.9 2.1 1 1 1 2 2 2 0 Autophagy protein Apg17 EF-hand_7 PF13499.6 KFO99073.1 - 0.0013 19.1 0.0 0.0019 18.6 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFO99073.1 - 0.0037 16.7 3.4 0.14 11.8 0.7 2.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFO99073.1 - 0.0049 16.7 0.1 0.079 12.9 0.1 2.5 3 0 0 3 3 3 1 EF-hand domain UPF0154 PF03672.13 KFO99073.1 - 0.019 15.0 1.2 0.03 14.3 1.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) TOPRIM_C PF16898.5 KFO99073.1 - 0.077 13.3 0.2 0.1 12.9 0.2 1.1 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM ANAPC4_WD40 PF12894.7 KFO99074.1 - 7.7e-07 29.3 0.0 4.3e-05 23.7 0.0 2.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFO99074.1 - 0.00089 20.0 0.1 0.15 13.0 0.0 2.9 3 0 0 3 3 3 1 WD domain, G-beta repeat WDCP PF15390.6 KFO99074.1 - 0.0044 15.5 0.1 0.0061 15.0 0.1 1.1 1 0 0 1 1 1 1 WD repeat and coiled-coil-containing protein family Nup214_FG PF18617.1 KFO99075.1 - 1.5e-29 102.3 27.2 1.5e-29 102.3 27.2 13.0 6 3 8 14 14 14 1 Nucleoporin Nup214 phenylalanine-glycine (FG) domain PAP2 PF01569.21 KFO99077.1 - 2.3e-13 50.1 3.0 3.5e-13 49.5 3.0 1.2 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KFO99077.1 - 0.00018 21.2 5.1 0.00034 20.4 5.1 1.5 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KFO99077.1 - 0.013 16.0 0.6 0.027 15.0 0.6 1.5 1 0 0 1 1 1 0 PAP2 superfamily C-terminal Myosin_head PF00063.21 KFO99078.1 - 3.2e-294 977.4 4.8 1.9e-293 974.9 4.8 2.4 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KFO99078.1 - 9.8e-157 523.7 278.8 1.2e-156 523.4 278.8 1.1 1 0 0 1 1 1 1 Myosin tail Filament PF00038.21 KFO99078.1 - 0.00036 20.2 15.4 0.00036 20.2 15.4 9.5 1 1 7 8 8 8 4 Intermediate filament protein Syntaxin-6_N PF09177.11 KFO99078.1 - 0.0086 16.6 7.9 0.0086 16.6 7.9 13.8 2 2 8 10 10 10 1 Syntaxin 6, N-terminal IQ PF00612.27 KFO99078.1 - 0.023 14.4 3.0 0.13 12.1 1.2 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_16 PF13191.6 KFO99078.1 - 0.15 12.4 0.0 0.15 12.4 0.0 6.6 2 1 1 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 KFO99078.1 - 0.21 11.8 0.0 0.21 11.8 0.0 5.7 4 3 2 6 6 6 0 AAA domain CAAX_1 PF15895.5 KFO99079.1 - 1.3 8.9 9.0 1.4 8.8 9.0 1.1 1 0 0 1 1 1 0 CAAX box cerebral protein 1 MORN PF02493.20 KFO99081.1 - 1.8e-10 40.0 13.4 6.7e-06 25.7 2.6 3.8 4 0 0 4 4 4 3 MORN repeat Fibrinogen_C PF00147.18 KFO99082.1 - 7.7e-74 248.2 10.0 9e-74 248.0 10.0 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Collagen PF01391.18 KFO99082.1 - 1.8e-09 37.2 24.1 3.3e-09 36.3 24.1 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Peptidase_S28 PF05577.12 KFO99083.1 - 1e-80 271.7 0.0 1.2e-80 271.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 KFO99083.1 - 6.6e-06 25.6 0.0 9.8e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2920 PF11144.8 KFO99083.1 - 0.00078 18.7 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Abhydrolase_1 PF00561.20 KFO99083.1 - 0.001 18.8 0.0 0.0029 17.3 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFO99083.1 - 0.0012 19.6 1.0 0.0079 16.8 0.9 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S37 PF05576.11 KFO99083.1 - 0.0021 16.8 0.0 0.0034 16.1 0.0 1.3 1 0 0 1 1 1 1 PS-10 peptidase S37 Peptidase_S9 PF00326.21 KFO99083.1 - 0.017 14.6 0.1 0.03 13.8 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Glyco_hydro_47 PF01532.20 KFO99084.1 - 1.3e-168 561.7 0.0 1.5e-168 561.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 UDPGP PF01704.18 KFO99085.1 - 8.6e-67 225.6 0.0 1.1e-66 225.2 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 KFO99085.1 - 0.00052 20.4 0.1 0.0016 18.8 0.0 1.8 2 0 0 2 2 2 1 MobA-like NTP transferase domain GDA1_CD39 PF01150.17 KFO99086.1 - 1.6e-68 231.3 0.0 1.8e-68 231.2 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family TMEM141 PF15110.6 KFO99087.1 - 7e-19 68.2 0.0 9.7e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 TMEM141 protein family GST_C_2 PF13410.6 KFO99088.1 - 6.5e-08 32.5 0.0 9.1e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFO99088.1 - 0.0034 17.6 0.0 0.0046 17.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ABC2_membrane_3 PF12698.7 KFO99089.1 - 1.1e-60 205.6 42.5 5.5e-43 147.4 12.8 3.6 4 0 0 4 4 4 2 ABC-2 family transporter protein ABC_tran PF00005.27 KFO99089.1 - 9.9e-58 194.5 0.0 1.6e-29 103.2 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KFO99089.1 - 5.4e-19 69.1 0.4 1.3e-06 28.5 0.0 4.6 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 KFO99089.1 - 0.00026 21.7 0.5 0.61 10.8 0.2 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4162) AAA_15 PF13175.6 KFO99089.1 - 0.00058 19.7 0.0 1.2 8.7 0.0 2.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 KFO99089.1 - 0.0016 19.0 0.9 0.47 10.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KFO99089.1 - 0.035 13.7 3.1 1.8 8.1 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 KFO99089.1 - 0.13 12.5 0.0 27 5.1 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 KFO99089.1 - 0.15 12.0 0.3 2.2 8.2 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase K_channel_TID PF07941.11 KFO99089.1 - 2.3 8.7 4.0 5.8 7.4 4.0 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Glyco_transf_10 PF00852.19 KFO99090.1 - 2e-57 193.7 1.0 2.7e-57 193.3 1.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 KFO99090.1 - 5.5e-33 113.7 0.0 1.2e-32 112.6 0.0 1.6 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal mIF3 PF14877.6 KFO99090.1 - 0.061 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial translation initiation factor Pou PF00157.17 KFO99091.1 - 3.1e-31 107.2 0.7 8.2e-31 105.8 0.1 1.9 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KFO99091.1 - 1.1e-18 66.8 0.3 2.2e-18 65.8 0.3 1.5 1 0 0 1 1 1 1 Homeodomain DUF2497 PF10691.9 KFO99091.1 - 0.041 14.3 0.2 14 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) Homeobox_KN PF05920.11 KFO99091.1 - 0.066 13.1 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain NPDC1 PF06809.11 KFO99092.1 - 3.7e-79 266.3 8.4 1.4e-77 261.1 8.4 2.0 1 1 0 1 1 1 1 Neural proliferation differentiation control-1 protein (NPDC1) TMEM100 PF16311.5 KFO99092.1 - 0.057 13.0 0.2 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 Transmembrane protein 100 Lipocalin PF00061.23 KFO99093.1 - 0.0032 17.7 0.0 0.0034 17.6 0.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.23 KFO99094.1 - 9.4e-27 94.0 0.0 1.1e-26 93.7 0.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.23 KFO99095.1 - 3.6e-22 79.1 0.0 4.3e-22 78.9 0.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family WD40 PF00400.32 KFO99096.1 - 7.4e-07 29.8 0.4 7.4e-07 29.8 0.4 2.6 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO99096.1 - 0.15 12.4 0.0 0.54 10.6 0.0 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain TRAF_BIRC3_bd PF16673.5 KFO99097.1 - 5.7e-32 109.3 4.3 7.5e-32 108.9 2.3 2.1 2 0 0 2 2 2 1 TNF receptor-associated factor BIRC3 binding domain zf-TRAF PF02176.18 KFO99097.1 - 6.6e-07 29.9 0.5 6.6e-07 29.9 0.5 2.5 2 0 0 2 2 2 1 TRAF-type zinc finger zf-C3HC4 PF00097.25 KFO99097.1 - 1.3e-05 24.9 9.0 5.1e-05 23.0 9.0 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFO99097.1 - 0.0011 19.1 5.0 0.0091 16.1 5.3 2.5 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KFO99097.1 - 0.0036 17.1 7.4 0.009 15.9 7.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFO99097.1 - 0.0052 16.6 7.8 0.017 15.0 7.8 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 KFO99097.1 - 0.0064 16.4 4.0 0.023 14.6 4.0 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KFO99097.1 - 0.007 16.2 3.4 0.007 16.2 3.4 2.5 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-TRAF_2 PF15965.5 KFO99097.1 - 0.028 14.9 1.6 0.028 14.9 1.6 3.1 3 1 0 3 3 3 0 TRAF-like zinc-finger zf-RING_10 PF16685.5 KFO99097.1 - 0.033 14.3 4.4 0.093 12.9 4.4 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_5 PF14634.6 KFO99097.1 - 0.064 13.2 9.0 0.18 11.8 9.0 1.8 1 0 0 1 1 1 0 zinc-RING finger domain MATH PF00917.26 KFO99097.1 - 0.083 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 MATH domain zf-RING_UBOX PF13445.6 KFO99097.1 - 0.14 12.2 9.0 0.12 12.4 6.3 2.5 2 0 0 2 2 2 0 RING-type zinc-finger Sina PF03145.16 KFO99097.1 - 0.16 11.9 2.6 0.16 11.9 0.6 1.9 2 0 0 2 2 2 0 Seven in absentia protein family DUF4424 PF14415.6 KFO99097.1 - 0.22 10.8 0.0 0.34 10.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4424) zf-RING_2 PF13639.6 KFO99097.1 - 0.24 11.8 7.5 1.1 9.6 7.5 2.2 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 KFO99097.1 - 4.6 7.1 11.5 2.4 8.0 7.9 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain LIM PF00412.22 KFO99098.1 - 6.5e-34 116.0 28.1 9.6e-17 61.0 11.3 2.3 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 KFO99098.1 - 3.9e-18 65.0 2.5 8.9e-18 63.9 2.5 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO99098.1 - 0.00012 21.9 0.0 0.00027 20.8 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain DUF2464 PF10240.9 KFO99099.1 - 4.3e-84 282.1 0.0 5e-84 281.9 0.0 1.0 1 0 0 1 1 1 1 Multivesicular body subunit 12 CRIM PF16978.5 KFO99100.1 - 2.7e-36 124.8 0.0 5.7e-36 123.7 0.0 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1 PF05422.12 KFO99100.1 - 9.5e-33 113.7 11.8 6.2e-30 104.6 7.4 3.6 2 1 0 2 2 2 1 Stress-activated map kinase interacting protein 1 (SIN1) SIN1_PH PF16979.5 KFO99100.1 - 3.7e-28 98.0 0.3 6.8e-28 97.1 0.3 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology RasGAP PF00616.19 KFO99101.1 - 8.2e-36 123.7 0.1 2.4e-35 122.1 0.1 1.9 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase VPS9 PF02204.18 KFO99101.1 - 1.3e-28 99.2 0.0 3.9e-28 97.7 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KFO99101.1 - 3e-12 46.6 0.2 1.1e-11 44.9 0.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) EF-hand_14 PF17959.1 KFO99101.1 - 0.047 14.0 0.1 0.32 11.4 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain SURF2 PF05477.11 KFO99101.1 - 1.8 8.2 9.1 2.5 7.7 0.1 2.6 3 0 0 3 3 3 0 Surfeit locus protein 2 (SURF2) HSP70 PF00012.20 KFO99102.1 - 1.7e-262 872.0 10.1 2e-262 871.8 10.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFO99102.1 - 3.3e-17 62.3 0.1 8e-17 61.0 0.1 1.6 1 1 0 1 1 1 1 MreB/Mbl protein Hydantoinase_A PF01968.18 KFO99102.1 - 0.0037 16.6 0.2 0.013 14.8 0.1 1.9 1 1 0 1 1 1 1 Hydantoinase/oxoprolinase DDR PF08841.10 KFO99102.1 - 0.0086 15.1 1.1 0.024 13.7 0.6 1.8 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 KFO99102.1 - 0.036 13.8 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Radial_spoke_3 PF06098.11 KFO99102.1 - 1 8.6 12.9 0.031 13.6 6.1 1.8 2 0 0 2 2 2 0 Radial spoke protein 3 Kelch_3 PF13415.6 KFO99103.1 - 9.7e-27 92.7 5.5 3.6e-07 30.3 0.1 4.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 KFO99103.1 - 1.2e-22 79.2 0.0 6.7e-08 32.0 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 KFO99103.1 - 1.6e-22 79.0 3.0 1.1e-05 25.3 0.1 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 KFO99103.1 - 3.8e-22 77.8 1.6 3.6e-06 27.1 0.0 4.1 2 1 2 4 4 4 3 Kelch motif Kelch_4 PF13418.6 KFO99103.1 - 1.3e-15 57.1 9.0 1.6e-05 24.8 0.0 5.2 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KFO99103.1 - 2.4e-14 52.7 2.8 5.6e-06 26.1 0.0 4.4 4 1 0 4 4 4 3 Kelch motif Metallophos PF00149.28 KFO99104.1 - 1.1e-36 127.3 0.2 1.4e-36 127.0 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase P16-Arc PF04699.14 KFO99105.1 - 7.5e-42 143.3 0.0 8.2e-42 143.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 KFO99105.1 - 0.016 15.5 0.0 0.023 15.0 0.0 1.3 1 0 0 1 1 1 0 Dip2/Utp12 Family NIL PF09383.10 KFO99105.1 - 0.027 14.3 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 NIL domain GRIP PF01465.20 KFO99106.1 - 7.5e-15 54.6 0.5 2.5e-14 52.9 0.5 2.0 1 0 0 1 1 1 1 GRIP domain Spc7 PF08317.11 KFO99106.1 - 7.9 5.3 149.8 0.25 10.2 22.4 6.7 1 1 6 7 7 7 0 Spc7 kinetochore protein SCAI PF12070.8 KFO99107.1 - 1.1e-199 664.7 9.6 4.4e-199 662.8 9.6 1.9 1 1 0 1 1 1 1 Protein SCAI Ribosomal_L29 PF00831.23 KFO99108.1 - 0.00054 19.9 0.7 0.00054 19.9 0.7 2.7 2 1 1 3 3 3 1 Ribosomal L29 protein XFP_N PF09364.10 KFO99108.1 - 0.038 12.8 0.0 0.038 12.8 0.0 1.0 1 0 0 1 1 1 0 XFP N-terminal domain zf-C4 PF00105.18 KFO99109.1 - 3.9e-28 97.7 17.9 8.2e-28 96.7 17.9 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFO99109.1 - 2.5e-26 92.6 5.6 5e-26 91.6 5.6 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor 7tm_2 PF00002.24 KFO99110.1 - 2.5e-46 158.0 24.2 2.5e-46 158.0 24.2 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Pentaxin PF00354.17 KFO99110.1 - 5.9e-26 91.3 0.1 1.1e-25 90.4 0.1 1.4 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.6 KFO99110.1 - 2e-13 50.7 0.1 3.3e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily GPS PF01825.21 KFO99110.1 - 8.3e-11 42.2 1.1 8.3e-11 42.2 1.1 2.9 3 0 0 3 3 3 1 GPCR proteolysis site, GPS, motif GAIN PF16489.5 KFO99110.1 - 1.1e-05 25.0 0.1 2e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Dicty_CAR PF05462.11 KFO99110.1 - 1.9e-05 24.0 10.0 3.2e-05 23.2 10.0 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Lectin_C PF00059.21 KFO99110.1 - 0.014 16.2 2.6 0.22 12.2 0.0 3.3 4 0 0 4 4 4 0 Lectin C-type domain Tex_N PF09371.10 KFO99110.1 - 0.039 13.6 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 Tex-like protein N-terminal domain Laminin_G_2 PF02210.24 KFO99110.1 - 0.046 14.3 0.0 0.13 12.8 0.0 1.8 1 0 0 1 1 1 0 Laminin G domain RACo_linker PF17650.1 KFO99110.1 - 0.11 12.3 0.0 7.8 6.4 0.0 2.5 2 0 0 2 2 2 0 RACo linker region DUF5589 PF17672.1 KFO99110.1 - 0.24 11.3 1.9 0.81 9.6 1.9 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5589) Proteasome PF00227.26 KFO99111.1 - 7.7e-51 172.3 0.3 1e-50 171.9 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KFO99111.1 - 1.9e-14 52.7 0.1 1.9e-14 52.7 0.1 2.2 3 0 0 3 3 3 1 Proteasome beta subunits C terminal Pkinase PF00069.25 KFO99112.1 - 4.4e-48 163.9 0.2 5.8e-48 163.5 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO99112.1 - 1.2e-34 119.8 0.0 1.7e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RecG_N PF17190.4 KFO99112.1 - 0.042 14.6 0.6 0.27 12.0 0.3 2.5 3 1 0 3 3 3 0 RecG N-terminal helical domain DENN PF02141.21 KFO99113.1 - 1.8e-47 161.7 2.9 4.4e-47 160.4 2.9 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KFO99113.1 - 3.1e-11 43.8 1.0 3.1e-11 43.8 1.0 2.3 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 KFO99113.1 - 9.5e-11 41.5 2.3 2e-10 40.5 2.3 1.6 1 0 0 1 1 1 1 dDENN domain EGF PF00008.27 KFO99114.1 - 1.1e-88 291.0 199.9 2.4e-10 40.5 8.1 15.3 15 0 0 15 15 15 15 EGF-like domain hEGF PF12661.7 KFO99114.1 - 3.7e-58 192.3 174.4 9.4e-08 32.4 4.1 17.0 16 1 0 16 16 16 13 Human growth factor-like EGF EGF_CA PF07645.15 KFO99114.1 - 6.6e-29 99.8 204.0 5.9e-05 23.2 8.1 15.4 11 4 4 15 15 15 12 Calcium-binding EGF domain EGF_2 PF07974.13 KFO99114.1 - 4.4e-10 39.7 226.7 0.0026 18.1 9.8 15.3 13 2 1 14 14 14 10 EGF-like domain EGF_3 PF12947.7 KFO99114.1 - 4.2e-08 33.2 180.6 0.13 12.4 4.8 15.2 13 3 1 14 14 14 10 EGF domain cEGF PF12662.7 KFO99114.1 - 5.5e-07 29.4 154.9 7.4e-05 22.6 1.7 17.1 17 1 0 17 17 17 8 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFO99114.1 - 0.0017 18.6 180.6 0.058 13.7 6.8 15.0 4 4 10 14 14 14 6 Coagulation Factor Xa inhibitory site DZF PF07528.14 KFO99115.1 - 4.1e-79 265.7 0.0 6.5e-79 265.0 0.0 1.3 1 0 0 1 1 1 1 DZF domain dsrm PF00035.26 KFO99115.1 - 3.7e-26 91.6 0.0 1.8e-13 51.0 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif SGP PF17228.2 KFO99115.1 - 0.0017 19.1 2.1 0.0017 19.1 2.1 1.8 2 0 0 2 2 2 1 Sulphur globule protein DND1_DSRM PF14709.7 KFO99115.1 - 0.0084 16.3 3.5 4.1 7.7 0.1 3.6 3 2 0 3 3 3 2 double strand RNA binding domain from DEAD END PROTEIN 1 JIP_LZII PF16471.5 KFO99115.1 - 0.43 10.8 2.8 0.37 11.0 0.3 2.1 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II RabGAP-TBC PF00566.18 KFO99116.1 - 2.1e-57 194.2 1.7 2.1e-57 194.2 1.7 2.5 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DUF3694 PF12473.8 KFO99116.1 - 3e-32 112.4 0.1 3e-32 112.4 0.1 3.0 3 1 0 3 3 3 1 Kinesin protein PID PF00640.23 KFO99116.1 - 5.1e-06 26.6 3.5 2.4e-05 24.4 0.0 3.1 3 1 0 3 3 3 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFO99116.1 - 0.0013 18.8 0.2 0.0053 16.9 0.0 2.1 2 0 0 2 2 2 1 Phosphotyrosine-binding domain UPF0242 PF06785.11 KFO99116.1 - 0.0037 17.4 7.5 0.0037 17.4 7.5 3.3 1 1 2 3 3 3 2 Uncharacterised protein family (UPF0242) N-terminus ERM PF00769.19 KFO99116.1 - 0.2 11.5 53.6 0.045 13.6 48.6 2.3 2 1 1 3 3 3 0 Ezrin/radixin/moesin family DUF3452 PF11934.8 KFO99116.1 - 0.76 9.3 12.5 1.3 8.6 0.7 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3452) AAA_15 PF13175.6 KFO99116.1 - 7.4 6.2 21.9 2.3 7.9 18.5 1.8 2 0 0 2 2 2 0 AAA ATPase domain BTB PF00651.31 KFO99117.1 - 2e-19 69.9 0.3 6.3e-19 68.2 0.3 1.9 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 KFO99117.1 - 4.2e-18 64.7 37.8 1.2e-05 25.5 2.6 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO99117.1 - 4.8e-16 58.4 19.1 1.2e-06 28.6 0.5 5.7 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFO99117.1 - 3.9e-12 45.9 36.8 0.00036 21.1 2.6 5.1 5 0 0 5 5 4 4 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFO99117.1 - 0.00042 20.0 22.9 0.0029 17.3 2.4 4.5 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-met PF12874.7 KFO99117.1 - 0.00051 20.3 22.6 0.031 14.7 1.9 4.6 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFO99117.1 - 0.00063 19.4 24.3 0.0053 16.5 2.3 4.4 4 0 0 4 4 4 3 zinc-finger C2H2-type DUF899 PF05988.12 KFO99117.1 - 0.012 15.2 0.1 0.012 15.2 0.1 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF899) zf-CHCC PF10276.9 KFO99117.1 - 0.11 12.5 3.6 0.15 12.1 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger domain zf-C2H2_2 PF12756.7 KFO99117.1 - 0.12 12.8 30.0 0.44 10.9 1.0 5.3 2 1 4 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KFO99117.1 - 0.13 12.6 19.3 2.3 8.6 0.1 4.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFO99117.1 - 0.18 11.6 7.9 16 5.4 0.0 4.3 1 1 3 4 4 4 0 GAGA factor zf-Dof PF02701.15 KFO99117.1 - 1.4 9.1 7.4 0.092 12.9 0.8 2.4 1 1 1 2 2 2 0 Dof domain, zinc finger ROQ_II PF18386.1 KFO99118.1 - 6.2e-34 115.6 1.3 4.2e-33 112.9 0.6 2.3 2 0 0 2 2 2 1 Roquin II domain zf-CCCH PF00642.24 KFO99118.1 - 2e-06 27.6 1.9 2e-06 27.6 1.9 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_UBOX PF13445.6 KFO99118.1 - 1.1e-05 25.3 7.5 1.1e-05 25.3 7.5 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFO99118.1 - 1.2e-05 25.5 7.4 1.2e-05 25.5 7.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KFO99118.1 - 1.5e-05 24.8 7.8 3.7e-05 23.6 7.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFO99118.1 - 9e-05 22.3 4.5 9e-05 22.3 4.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFO99118.1 - 0.00023 20.9 11.5 0.0049 16.7 8.0 3.3 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFO99118.1 - 0.002 18.2 6.6 0.002 18.2 6.6 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf_CCCH_4 PF18345.1 KFO99118.1 - 0.002 18.1 1.4 0.0049 16.9 1.4 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KFO99118.1 - 0.0025 17.6 1.0 0.0047 16.7 1.0 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-C3HC4 PF00097.25 KFO99118.1 - 0.0027 17.5 8.4 0.007 16.2 8.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Xin PF08043.12 KFO99118.1 - 0.0053 16.3 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Xin repeat zf-C3HC4_2 PF13923.6 KFO99118.1 - 0.0084 15.9 7.8 0.026 14.4 7.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KFO99118.1 - 0.79 9.9 8.0 0.29 11.3 5.0 1.8 2 0 0 2 2 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KFO99118.1 - 1.3 8.8 5.6 2.8 7.8 5.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 KFO99118.1 - 1.8 8.5 5.0 4.2 7.3 5.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Phosducin PF02114.16 KFO99119.1 - 6e-32 110.6 3.2 6.5e-32 110.5 3.2 1.0 1 0 0 1 1 1 1 Phosducin CcmD PF04995.14 KFO99119.1 - 2.7 8.1 5.7 0.39 10.8 2.0 1.5 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) An_peroxidase PF03098.15 KFO99120.1 - 2.6e-50 171.5 0.0 8.4e-43 146.7 0.0 2.7 1 1 1 2 2 2 2 Animal haem peroxidase EGF PF00008.27 KFO99120.1 - 1.2e-05 25.5 9.3 3e-05 24.2 9.3 1.7 1 0 0 1 1 1 1 EGF-like domain EGF_2 PF07974.13 KFO99120.1 - 0.037 14.4 11.6 0.071 13.5 11.6 1.4 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 KFO99120.1 - 0.093 13.4 6.0 0.22 12.2 6.0 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF RRF PF01765.19 KFO99121.1 - 7.8e-44 149.5 4.4 7.8e-44 149.5 4.4 1.4 2 0 0 2 2 2 1 Ribosome recycling factor YvbH_ext PF11724.8 KFO99121.1 - 0.02 15.2 0.4 0.04 14.2 0.4 1.5 1 0 0 1 1 1 0 YvbH-like oligomerisation region ChapFlgA_N PF17656.1 KFO99121.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 FlgA N-terminal domain YtxH PF12732.7 KFO99121.1 - 0.12 12.9 10.2 0.14 12.7 5.7 2.6 2 1 0 2 2 2 0 YtxH-like protein DUF883 PF05957.13 KFO99121.1 - 0.9 10.2 7.9 0.42 11.2 4.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF3810 PF12725.7 KFO99121.1 - 1.3 8.3 5.1 0.35 10.2 1.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) RRM_1 PF00076.22 KFO99122.1 - 5e-12 45.5 0.1 8.2e-12 44.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 KFO99122.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated LIM PF00412.22 KFO99123.1 - 2e-29 101.6 18.2 2.2e-15 56.6 3.0 2.3 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 KFO99123.1 - 2.6e-17 62.4 0.8 4.4e-17 61.7 0.8 1.4 1 0 0 1 1 1 1 Homeodomain zf-ACC PF17848.1 KFO99123.1 - 0.0024 17.9 0.4 0.069 13.2 0.0 2.9 2 0 0 2 2 2 1 Acetyl-coA carboxylase zinc finger domain MRP-L20 PF12824.7 KFO99123.1 - 0.017 15.3 0.2 0.017 15.3 0.2 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 Homeobox_KN PF05920.11 KFO99123.1 - 0.077 12.9 0.2 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 Homeobox KN domain zf-dskA_traR PF01258.17 KFO99123.1 - 0.24 11.4 8.8 0.44 10.5 0.0 3.2 3 0 0 3 3 2 0 Prokaryotic dksA/traR C4-type zinc finger TF_Zn_Ribbon PF08271.12 KFO99123.1 - 0.5 9.9 0.1 0.5 9.9 0.1 2.7 3 0 0 3 3 3 0 TFIIB zinc-binding Arc_trans_TRASH PF08394.10 KFO99123.1 - 0.51 10.7 11.4 3.9 7.9 0.6 3.4 3 0 0 3 3 3 0 Archaeal TRASH domain zinc_ribbon_2 PF13240.6 KFO99123.1 - 0.54 10.1 8.3 20 5.1 0.1 4.5 5 0 0 5 5 5 0 zinc-ribbon domain DUF2175 PF09943.9 KFO99123.1 - 5.3 7.4 10.5 0.55 10.6 0.4 3.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) Sgf11 PF08209.11 KFO99123.1 - 6.3 6.5 11.9 2.5 7.7 0.1 3.7 4 0 0 4 4 4 0 Sgf11 (transcriptional regulation protein) YhfH PF14149.6 KFO99123.1 - 6.4 6.8 11.9 7.7 6.6 0.3 3.6 4 0 0 4 4 4 0 YhfH-like protein CHCH PF06747.13 KFO99125.1 - 1.4e-08 34.7 1.2 2.3e-08 34.0 1.2 1.4 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 KFO99125.1 - 0.04 14.0 0.5 0.061 13.3 0.5 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 KFO99125.1 - 0.21 11.7 4.7 0.21 11.6 1.7 2.2 2 1 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, TTL PF03133.15 KFO99127.1 - 3.9e-67 226.5 0.0 5.9e-67 225.9 0.0 1.3 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 KFO99127.1 - 6.7e-08 32.1 0.0 0.0001 21.6 0.0 2.5 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 KFO99127.1 - 4.5e-06 26.1 0.0 0.0072 15.6 0.0 2.8 2 1 1 3 3 3 2 YheC/D like ATP-grasp RimK PF08443.11 KFO99127.1 - 0.0085 15.7 0.0 2.9 7.5 0.0 2.2 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 KFO99127.1 - 0.026 14.6 0.0 0.53 10.3 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain Band_7 PF01145.25 KFO99128.1 - 5.5e-35 121.0 0.5 6.8e-35 120.7 0.5 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KFO99128.1 - 0.00046 19.9 0.1 0.00072 19.3 0.1 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family GP68 PF17469.2 KFO99128.1 - 0.12 12.8 0.1 0.27 11.7 0.1 1.6 1 0 0 1 1 1 0 Phage protein Gp68 Gelsolin PF00626.22 KFO99129.1 - 1.4e-107 351.8 0.4 1.5e-20 72.9 0.0 6.2 6 0 0 6 6 6 6 Gelsolin repeat Lipoprotein_Ltp PF07553.11 KFO99129.1 - 0.0051 17.0 0.1 2.1 8.6 0.1 2.5 2 0 0 2 2 2 2 Host cell surface-exposed lipoprotein POC3_POC4 PF10448.9 KFO99129.1 - 0.058 13.4 0.0 0.24 11.4 0.0 2.0 1 1 1 2 2 2 0 20S proteasome chaperone assembly proteins 3 and 4 CutA1 PF03091.15 KFO99129.1 - 0.14 12.0 0.8 8.2 6.4 0.0 3.2 4 0 0 4 4 4 0 CutA1 divalent ion tolerance protein Ras PF00071.22 KFO99130.1 - 8.6e-61 204.3 0.1 9.9e-61 204.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO99130.1 - 2.5e-32 111.6 0.0 3.8e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO99130.1 - 1.7e-12 47.2 0.0 2.1e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFO99130.1 - 2.8e-05 23.7 0.0 0.0013 18.3 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFO99130.1 - 4.9e-05 23.4 0.0 9.3e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFO99130.1 - 0.00031 20.7 0.1 0.64 9.9 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KFO99130.1 - 0.0014 18.1 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 KFO99130.1 - 0.0027 17.5 0.0 0.065 13.0 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 KFO99130.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF1863 PF08937.11 KFO99130.1 - 0.055 13.8 0.0 0.096 13.0 0.0 1.5 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) Septin PF00735.18 KFO99130.1 - 0.082 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Septin AAA PF00004.29 KFO99130.1 - 0.11 12.9 0.0 0.47 10.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFO99130.1 - 0.14 12.4 0.1 0.47 10.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain LRR_9 PF14580.6 KFO99131.1 - 3.5e-20 72.2 1.9 3.5e-20 72.2 1.9 4.7 4 1 1 5 5 5 2 Leucine-rich repeat LRR_4 PF12799.7 KFO99131.1 - 5.8e-14 52.0 22.7 4.2e-07 30.2 0.3 5.9 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFO99131.1 - 1.6e-12 47.0 21.4 1.6e-07 31.0 3.3 5.0 3 1 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 KFO99131.1 - 4.7e-06 26.2 9.8 1.2 9.3 0.1 5.1 4 0 0 4 4 4 3 Leucine Rich repeat Fez1 PF06818.15 KFO99131.1 - 0.004 17.6 21.2 0.004 17.6 21.2 15.2 4 2 11 15 15 15 2 Fez1 DUF3287 PF11690.8 KFO99131.1 - 0.016 14.9 0.6 0.016 14.9 0.6 8.7 8 3 4 12 12 12 0 Protein of unknown function (DUF3287) LRR_1 PF00560.33 KFO99131.1 - 0.072 13.7 16.1 4.4 8.2 0.1 6.1 5 0 0 5 5 5 0 Leucine Rich Repeat Halo_GVPC PF05465.13 KFO99131.1 - 9.3 6.6 8.3 68 3.9 0.2 4.2 4 0 0 4 4 4 0 Halobacterial gas vesicle protein C (GVPC) repeat TED_complement PF07678.14 KFO99132.1 - 4.5e-88 295.3 0.8 6.6e-88 294.7 0.8 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain MG4 PF17789.1 KFO99132.1 - 9.2e-31 105.9 1.2 2.2e-29 101.4 0.2 3.1 3 0 0 3 3 3 1 Macroglobulin domain MG4 MG1 PF17790.1 KFO99132.1 - 2.9e-30 104.7 2.7 1.6e-27 95.9 0.1 3.7 3 0 0 3 3 3 1 Macroglobulin domain MG1 A2M_BRD PF07703.14 KFO99132.1 - 3.4e-26 92.3 0.4 1.4e-24 87.1 0.1 3.0 2 0 0 2 2 2 1 Alpha-2-macroglobulin bait region domain A2M PF00207.22 KFO99132.1 - 6.4e-25 86.8 1.1 5.8e-24 83.8 0.1 3.0 3 0 0 3 3 3 1 Alpha-2-macroglobulin family A2M_recep PF07677.14 KFO99132.1 - 1.9e-22 79.8 0.0 7.3e-22 77.9 0.0 2.1 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain NTR PF01759.21 KFO99132.1 - 1.9e-22 79.1 0.1 6.1e-22 77.5 0.1 1.9 1 0 0 1 1 1 1 UNC-6/NTR/C345C module MG2 PF01835.19 KFO99132.1 - 1.6e-13 50.9 0.0 7.6e-13 48.7 0.0 2.3 1 0 0 1 1 1 1 MG2 domain ANATO PF01821.18 KFO99132.1 - 2e-08 35.0 8.4 5.1e-08 33.6 8.4 1.8 1 0 0 1 1 1 1 Anaphylotoxin-like domain MG3 PF17791.1 KFO99132.1 - 6.6e-05 23.1 0.0 0.0002 21.6 0.0 1.9 1 0 0 1 1 1 1 Macroglobulin domain MG3 Prenyltrans PF00432.21 KFO99132.1 - 0.0028 17.3 0.2 0.6 9.9 0.0 2.8 2 0 0 2 2 2 1 Prenyltransferase and squalene oxidase repeat PilZ PF07238.14 KFO99132.1 - 0.0038 17.5 0.0 0.13 12.6 0.0 3.2 3 0 0 3 3 3 1 PilZ domain BAT2_N PF07001.11 KFO99133.1 - 2.4e-66 223.9 9.6 2.4e-66 223.9 9.6 6.2 6 1 2 8 8 8 1 BAT2 N-terminus PMT PF02366.18 KFO99134.1 - 3.3e-89 298.7 24.0 3.3e-89 298.7 24.0 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KFO99134.1 - 3.5e-54 183.4 9.4 3.5e-54 183.4 9.4 2.8 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KFO99134.1 - 2.9e-12 46.8 0.2 4.8e-12 46.1 0.2 1.4 1 0 0 1 1 1 1 MIR domain PRK PF00485.18 KFO99135.1 - 5.5e-51 173.1 0.1 6.4e-51 172.9 0.1 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CoaE PF01121.20 KFO99135.1 - 9.6e-06 25.4 0.6 2.8e-05 23.9 0.6 1.7 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KFO99135.1 - 4.1e-05 24.1 0.1 8.8e-05 23.1 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KFO99135.1 - 0.011 16.2 4.1 1.3 9.5 4.1 2.4 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KFO99135.1 - 0.036 13.3 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 KFO99135.1 - 0.063 12.3 0.0 0.089 11.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 KFO99135.1 - 0.068 13.3 0.0 0.16 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 KFO99135.1 - 0.11 12.2 0.7 1.2 8.8 0.1 2.3 2 1 0 2 2 2 0 Cytidylate kinase KTI12 PF08433.10 KFO99135.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 LTXXQ PF07813.12 KFO99135.1 - 0.14 12.9 0.1 0.22 12.2 0.1 1.3 1 0 0 1 1 1 0 LTXXQ motif family protein CD225 PF04505.12 KFO99137.1 - 8.8e-22 77.0 0.4 1.2e-21 76.6 0.4 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein GNVR PF13807.6 KFO99137.1 - 0.31 11.0 1.4 1.1 9.2 0.1 2.0 1 1 1 2 2 2 0 G-rich domain on putative tyrosine kinase DUF4190 PF13828.6 KFO99137.1 - 1.7 8.4 5.8 12 5.8 5.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4190) RasGEF PF00617.19 KFO99138.1 - 7.7e-53 179.3 0.6 3.2e-52 177.3 0.2 2.2 1 1 1 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KFO99138.1 - 1.4e-09 38.1 0.2 1.4e-09 38.1 0.2 3.1 4 0 0 4 4 4 1 RasGEF N-terminal motif Med27 PF11571.8 KFO99139.1 - 9.5e-28 96.4 0.2 1.8e-27 95.5 0.2 1.5 1 0 0 1 1 1 1 Mediator complex subunit 27 Laminin_N PF00055.17 KFO99140.1 - 4.7e-50 170.4 0.0 4.7e-50 170.4 0.0 3.2 3 1 1 4 4 4 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 KFO99140.1 - 1.8e-21 76.0 66.7 4.5e-09 36.3 13.8 4.6 3 1 1 4 4 4 3 Laminin EGF domain EGF PF00008.27 KFO99140.1 - 0.0011 19.2 7.7 0.0011 19.2 7.7 5.5 4 2 2 6 6 6 1 EGF-like domain BNR PF02012.20 KFO99140.1 - 0.012 15.5 1.1 1.5 9.2 0.0 3.2 2 0 0 2 2 2 0 BNR/Asp-box repeat F5_F8_type_C PF00754.25 KFO99140.1 - 0.11 12.6 0.1 0.25 11.4 0.0 1.6 2 0 0 2 2 2 0 F5/8 type C domain AAA_11 PF13086.6 KFO99141.1 - 3.4e-64 217.2 1.1 1.7e-63 214.9 1.1 2.3 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 KFO99141.1 - 1.6e-54 184.6 0.5 6e-54 182.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain SEN1_N PF12726.7 KFO99141.1 - 5.2e-14 51.4 4.6 5.2e-14 51.4 4.6 2.7 2 1 0 2 2 2 1 SEN1 N terminal AAA_19 PF13245.6 KFO99141.1 - 2e-08 34.7 0.0 3.3e-07 30.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFO99141.1 - 9.3e-07 28.8 0.0 0.015 15.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KFO99141.1 - 5.4e-06 26.3 3.7 0.36 10.5 0.1 4.9 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KFO99141.1 - 4.5e-05 23.7 0.5 0.0023 18.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFO99141.1 - 0.0044 17.4 0.0 0.017 15.5 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain UvrD-helicase PF00580.21 KFO99141.1 - 0.018 14.5 4.6 0.019 14.5 0.3 2.9 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain DUF4164 PF13747.6 KFO99141.1 - 0.085 13.1 7.4 0.24 11.7 7.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Myb_DNA-bind_6 PF13921.6 KFO99142.1 - 9.6e-16 57.8 7.4 1.2e-12 47.9 0.2 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFO99142.1 - 5.8e-14 52.0 9.8 8e-08 32.4 0.1 3.8 4 1 0 4 4 4 2 Myb-like DNA-binding domain Poxvirus_B22R_N PF13169.6 KFO99142.1 - 0.0027 18.2 2.4 0.0038 17.7 0.1 2.5 3 0 0 3 3 3 1 Poxvirus B22R protein N-terminal WbqC PF08889.11 KFO99142.1 - 0.026 14.4 0.5 0.27 11.1 0.0 2.5 2 1 0 3 3 3 0 WbqC-like protein family Phage_TAC_5 PF08890.11 KFO99142.1 - 0.1 12.6 2.2 0.21 11.6 0.1 2.6 3 0 0 3 3 3 0 Phage XkdN-like tail assembly chaperone protein, TAC Myb_DNA-bind_4 PF13837.6 KFO99142.1 - 0.36 11.2 12.1 0.62 10.5 7.2 3.3 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Homeodomain PF00046.29 KFO99143.1 - 2.5e-22 78.5 5.9 4e-22 77.8 5.9 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO99143.1 - 0.056 13.3 0.2 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 Homeobox KN domain DEAD PF00270.29 KFO99144.1 - 4.6e-25 88.4 0.0 1.3e-24 86.9 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFO99144.1 - 5.9e-25 87.8 0.0 1.5e-24 86.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFO99144.1 - 6.9e-15 55.0 0.1 1.6e-14 53.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KFO99144.1 - 0.00013 22.0 0.2 0.00034 20.7 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFO99144.1 - 0.00057 19.2 0.0 0.0096 15.2 0.0 2.2 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase FF PF01846.19 KFO99144.1 - 0.14 12.3 1.1 1.1 9.5 0.1 2.4 2 0 0 2 2 2 0 FF domain TFIIIC_delta PF12657.7 KFO99145.1 - 1.4e-09 38.2 0.0 1.7e-08 34.6 0.0 2.4 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 KFO99145.1 - 1.4e-05 24.9 1.3 2.5e-05 24.2 0.2 2.1 2 0 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex FRB_dom PF08771.11 KFO99146.1 - 0.079 13.4 0.4 0.12 12.8 0.4 1.4 1 1 0 1 1 1 0 FKBP12-rapamycin binding domain Ubiq-Cytc-red_N PF09165.10 KFO99147.1 - 4.9e-28 97.8 4.9 1.1e-27 96.7 4.9 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal UCR_TM PF02921.14 KFO99147.1 - 2e-27 95.4 3.9 3.5e-27 94.7 3.9 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 KFO99147.1 - 7e-13 48.3 0.1 2.3e-12 46.7 0.1 1.9 2 1 0 2 2 2 1 Rieske [2Fe-2S] domain Isochorismatase PF00857.20 KFO99147.1 - 0.066 13.4 0.2 2.1 8.5 0.2 2.1 1 1 0 1 1 1 0 Isochorismatase family Oxidored_q6 PF01058.22 KFO99147.1 - 0.094 12.5 0.0 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase, 20 Kd subunit V-set PF07686.17 KFO99148.1 - 0.00042 20.5 0.0 0.00052 20.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFO99148.1 - 0.01 15.9 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO99148.1 - 0.046 14.3 0.0 0.058 14.0 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain UPF0086 PF01868.16 KFO99149.1 - 1.4e-23 82.6 0.1 1.4e-23 82.6 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function UPF0086 FYVE PF01363.21 KFO99150.1 - 6.4e-18 64.7 7.1 1.2e-17 63.8 7.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 KFO99150.1 - 5.7e-09 36.4 0.4 1.1e-08 35.5 0.2 1.6 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 KFO99150.1 - 0.0002 21.2 0.6 0.007 16.2 0.6 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 KFO99150.1 - 0.00042 20.3 0.1 0.00081 19.4 0.1 1.4 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.16 KFO99150.1 - 0.0039 17.4 8.1 0.0063 16.7 7.9 1.5 1 1 0 1 1 1 1 FYVE-type zinc finger DUF1835 PF08874.10 KFO99150.1 - 0.015 15.5 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) C1_2 PF03107.16 KFO99150.1 - 0.034 14.5 3.8 0.055 13.8 2.2 2.1 2 0 0 2 2 2 0 C1 domain PH_6 PF15406.6 KFO99150.1 - 0.044 14.1 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain tRNA_bind_3 PF17176.4 KFO99150.1 - 0.082 13.2 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 tRNA-binding domain OrfB_Zn_ribbon PF07282.11 KFO99150.1 - 1.8 8.6 6.8 3.9 7.5 6.8 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-RING_4 PF14570.6 KFO99150.1 - 4.1 7.3 8.6 43 4.0 0.0 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Gly-zipper_YMGG PF13441.6 KFO99151.1 - 9.2 6.1 15.1 17 5.3 15.1 1.5 1 1 0 1 1 1 0 YMGG-like Gly-zipper Cyclin_N PF00134.23 KFO99152.1 - 8.4e-44 148.4 1.3 1.5e-43 147.6 1.3 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFO99152.1 - 7.5e-19 68.0 0.1 2.3e-18 66.4 0.0 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain Prefoldin PF02996.17 KFO99153.1 - 2.6e-16 59.6 0.0 2.6e-16 59.6 0.0 2.2 3 0 0 3 3 3 1 Prefoldin subunit Prefoldin_3 PF13758.6 KFO99153.1 - 4.3e-10 39.5 0.0 1.6e-09 37.7 0.0 2.1 1 0 0 1 1 1 1 Prefoldin subunit SIN1 PF05422.12 KFO99153.1 - 0.0014 19.2 0.8 0.0014 19.2 0.8 2.7 3 0 0 3 3 3 1 Stress-activated map kinase interacting protein 1 (SIN1) DUF1639 PF07797.14 KFO99153.1 - 2.4 8.2 4.3 1.6 8.8 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1639) zf-C2H2_assoc PF16606.5 KFO99154.1 - 3e-40 136.3 20.8 3.4e-40 136.1 17.2 3.0 2 0 0 2 2 2 1 Unstructured conserved, between two C2H2-type zinc-fingers zf-C2H2 PF00096.26 KFO99154.1 - 6.1e-32 108.3 74.1 2.3e-05 24.6 4.0 10.5 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO99154.1 - 1.3e-25 87.8 75.5 0.0022 18.7 2.8 10.8 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFO99154.1 - 4e-20 71.3 82.3 6.7e-08 32.6 2.4 12.4 13 0 0 13 13 12 6 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFO99154.1 - 8.7e-15 54.2 61.4 2.8e-07 30.1 0.9 10.5 11 0 0 11 11 11 4 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KFO99154.1 - 8.6e-08 32.4 48.6 0.0061 16.8 1.7 7.8 6 3 1 7 7 7 5 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 KFO99154.1 - 0.00039 20.2 10.0 0.7 9.7 0.1 5.9 5 2 2 7 7 7 1 GAGA factor zf-C2H2_2 PF12756.7 KFO99154.1 - 0.0099 16.2 42.6 4.3 7.7 0.1 10.0 5 3 4 9 9 9 1 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 KFO99154.1 - 0.01 15.9 33.0 0.52 10.5 3.3 6.2 5 2 1 6 6 6 0 Zinc ribbon domain Actin_micro PF17003.5 KFO99154.1 - 0.01 15.0 23.0 7.5 5.6 0.2 6.0 4 2 1 5 5 5 0 Putative actin-like family zf-C2H2_3rep PF18868.1 KFO99154.1 - 0.017 15.8 2.7 0.017 15.8 2.7 5.4 5 2 3 8 8 8 0 Zinc finger C2H2-type, 3 repeats DUF3268 PF11672.8 KFO99154.1 - 0.034 14.5 15.2 0.035 14.4 1.2 3.9 4 0 0 4 4 3 0 zinc-finger-containing domain CpXC PF14353.6 KFO99154.1 - 0.037 14.1 26.2 6.5 6.8 0.3 7.1 5 3 3 8 8 7 0 CpXC protein TerY_C PF15616.6 KFO99154.1 - 0.51 10.5 8.0 10 6.2 0.0 3.6 4 0 0 4 4 3 0 TerY-C metal binding domain DZR PF12773.7 KFO99154.1 - 0.55 10.3 22.5 0.14 12.2 0.4 5.4 5 1 0 5 5 5 0 Double zinc ribbon ARS2 PF04959.13 KFO99154.1 - 3.1 8.1 13.4 9 6.6 0.0 4.8 3 1 1 4 4 4 0 Arsenite-resistance protein 2 zf_C2H2_ZHX PF18387.1 KFO99154.1 - 3.4 7.4 25.2 0.61 9.8 0.4 5.9 4 2 2 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 KFO99155.1 - 2.5e-10 40.6 20.8 0.0063 16.8 1.2 5.2 3 2 1 4 4 4 4 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KFO99155.1 - 1.7e-09 37.6 27.3 0.034 14.6 2.9 5.8 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO99155.1 - 2.2e-08 34.2 22.0 0.062 14.2 2.6 5.8 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFO99155.1 - 8.1e-06 25.7 21.5 0.024 14.6 2.4 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 KFO99155.1 - 0.00067 20.0 8.4 0.026 14.9 2.1 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KFO99155.1 - 0.005 17.3 11.6 2.5 8.6 0.5 5.1 5 0 0 5 5 5 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 KFO99155.1 - 0.0054 17.0 14.9 0.058 13.7 0.8 4.8 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KFO99155.1 - 0.038 14.1 10.1 6.4 7.0 0.1 5.0 5 0 0 5 5 5 0 Zinc ribbon domain DUF678 PF05077.12 KFO99155.1 - 0.061 13.5 3.7 20 5.4 0.0 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF678) zf-C2H2_3rep PF18868.1 KFO99155.1 - 0.082 13.6 15.1 0.42 11.3 0.8 5.1 4 1 1 5 5 5 0 Zinc finger C2H2-type, 3 repeats PyrI_C PF02748.15 KFO99155.1 - 0.16 11.9 2.3 4.5 7.2 0.1 3.3 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Homeodomain PF00046.29 KFO99155.1 - 0.21 11.4 0.4 0.92 9.4 0.2 2.4 2 0 0 2 2 2 0 Homeodomain zf-C2HC_2 PF13913.6 KFO99155.1 - 0.37 10.7 1.4 0.53 10.3 0.1 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 KFO99155.1 - 0.9 10.1 12.9 3.1 8.4 0.1 5.2 5 0 0 5 5 4 0 Zinc-finger double domain zf-C2H2_11 PF16622.5 KFO99155.1 - 1.2 8.9 14.4 0.34 10.7 2.1 3.9 4 0 0 4 4 4 0 zinc-finger C2H2-type OTT_1508_deam PF14441.6 KFO99155.1 - 1.6 8.8 4.3 3.8 7.6 0.1 3.0 3 0 0 3 3 3 0 OTT_1508-like deaminase zf-CpG_bind_C PF12269.8 KFO99155.1 - 3.3 7.4 12.1 0.35 10.6 0.4 3.4 5 0 0 5 5 5 0 CpG binding protein zinc finger C terminal domain zf-C2H2_9 PF16293.5 KFO99155.1 - 5.9 6.8 11.0 4.6 7.2 0.2 4.4 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2 PF00096.26 KFO99156.1 - 4e-14 52.2 76.1 0.011 16.1 3.3 9.6 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO99156.1 - 6.3e-14 51.5 71.8 0.0095 16.7 3.2 9.6 9 0 0 9 9 9 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFO99156.1 - 1.9e-09 37.5 68.7 0.00027 21.2 2.0 11.7 13 0 0 13 13 13 6 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFO99156.1 - 0.044 13.5 77.8 0.03 14.1 2.7 9.5 10 0 0 10 10 10 0 C2H2-type zinc-finger domain DUF5069 PF16798.5 KFO99156.1 - 0.091 13.0 0.1 6.3 7.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5069) zf_C2H2_ZHX PF18387.1 KFO99156.1 - 3.5 7.3 41.2 0.18 11.5 2.1 8.1 6 2 2 8 8 8 0 Zinc-fingers and homeoboxes C2H2 finger domain Dpy19 PF10034.9 KFO99157.1 - 3.3e-243 808.7 29.2 3.8e-243 808.5 29.2 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation Cadherin PF00028.17 KFO99158.1 - 1.1e-219 711.6 15.3 3.2e-19 69.2 0.0 15.3 15 0 0 15 15 15 15 Cadherin domain Laminin_G_2 PF02210.24 KFO99158.1 - 5.4e-29 101.3 0.2 5.5e-16 59.3 0.0 2.8 3 0 0 3 3 2 2 Laminin G domain Laminin_G_1 PF00054.23 KFO99158.1 - 4.3e-22 78.7 0.0 6.9e-12 45.7 0.0 2.6 2 0 0 2 2 2 2 Laminin G domain Cadherin_C PF01049.17 KFO99158.1 - 2.7e-12 47.2 0.4 7.4e-12 45.8 0.4 1.7 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_3 PF16184.5 KFO99158.1 - 9e-12 45.0 14.5 0.016 15.2 0.1 10.2 11 0 0 11 11 11 3 Cadherin-like Cadherin_2 PF08266.12 KFO99158.1 - 2e-10 40.4 0.1 0.032 14.1 0.0 7.5 7 0 0 7 7 7 1 Cadherin-like Cadherin_pro PF08758.11 KFO99158.1 - 3.8e-09 36.6 0.0 2.4e-05 24.4 0.0 5.9 6 0 0 6 6 6 1 Cadherin prodomain like EGF PF00008.27 KFO99158.1 - 2.3e-06 27.8 37.9 0.0015 18.8 10.1 3.7 3 0 0 3 3 3 2 EGF-like domain Cadherin_4 PF17803.1 KFO99158.1 - 3.8e-05 24.2 45.9 0.002 18.7 0.2 10.9 12 0 0 12 12 12 2 Bacterial cadherin-like domain Big_9 PF17963.1 KFO99158.1 - 0.0028 18.3 0.8 0.0028 18.3 0.8 8.6 10 0 0 10 10 9 2 Bacterial Ig domain cEGF PF12662.7 KFO99158.1 - 0.0029 17.5 23.2 0.0072 16.2 0.5 3.7 3 0 0 3 3 3 2 Complement Clr-like EGF-like hEGF PF12661.7 KFO99158.1 - 0.016 15.8 30.4 0.37 11.5 4.5 3.9 3 0 0 3 3 3 0 Human growth factor-like EGF He_PIG PF05345.12 KFO99158.1 - 0.22 11.7 7.3 24 5.2 0.0 6.7 7 0 0 7 7 7 0 Putative Ig domain dsDNA_bind PF01984.20 KFO99159.1 - 4.6e-30 104.1 3.7 5.1e-30 104.0 3.7 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Methyltransf_4 PF02390.17 KFO99159.1 - 0.053 13.0 0.2 0.094 12.2 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase PCI PF01399.27 KFO99159.1 - 0.072 13.6 0.0 0.11 13.1 0.0 1.3 1 1 0 1 1 1 0 PCI domain Ank_2 PF12796.7 KFO99160.1 - 3.1e-57 191.1 12.8 6.7e-16 58.7 0.1 6.9 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.30 KFO99160.1 - 9.1e-53 174.5 20.5 3.5e-08 33.5 0.2 9.4 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.6 KFO99160.1 - 3.9e-49 164.4 15.4 1.8e-10 41.1 0.5 9.2 4 3 5 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFO99160.1 - 5.5e-49 163.6 11.6 2e-10 40.7 0.6 9.5 5 2 5 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFO99160.1 - 2.1e-42 138.2 10.7 7.8e-05 22.8 0.0 10.2 9 0 0 9 9 9 9 Ankyrin repeat VPS9 PF02204.18 KFO99160.1 - 9.1e-23 80.5 0.3 3.4e-22 78.6 0.3 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Syntaxin_2 PF14523.6 KFO99161.1 - 0.0011 19.3 0.3 0.0021 18.4 0.3 1.5 1 0 0 1 1 1 1 Syntaxin-like protein Tic110 PF16940.5 KFO99161.1 - 0.0061 15.1 0.2 0.0079 14.7 0.2 1.1 1 0 0 1 1 1 1 Chloroplast envelope transporter LapD_MoxY_N PF16448.5 KFO99161.1 - 0.02 14.8 0.3 0.042 13.7 0.0 1.6 2 0 0 2 2 2 0 LapD/MoxY periplasmic domain DUF2155 PF09923.9 KFO99161.1 - 0.043 14.1 0.4 0.4 11.0 0.4 2.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2155) DUF1539 PF07560.11 KFO99161.1 - 0.046 13.8 0.1 0.092 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) DUF3219 PF11514.8 KFO99161.1 - 0.11 12.6 0.2 0.59 10.2 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3219) TUDOR PF00567.24 KFO99163.1 - 5.6e-13 49.0 2.0 6.9e-13 48.7 2.0 1.1 1 0 0 1 1 1 1 Tudor domain TUDOR PF00567.24 KFO99164.1 - 5.7e-08 32.8 0.0 1.8e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Tudor domain Helicase_C PF00271.31 KFO99164.1 - 2e-07 31.4 0.0 1.4e-06 28.6 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFO99164.1 - 1.3e-05 25.1 0.0 2.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AA_permease_2 PF13520.6 KFO99165.1 - 1e-63 215.6 39.2 1.3e-63 215.3 39.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFO99165.1 - 2.3e-25 89.2 40.7 4.7e-25 88.1 40.7 1.4 1 1 0 1 1 1 1 Amino acid permease DUF3098 PF11297.8 KFO99165.1 - 1.7 8.3 10.6 0.22 11.1 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3098) Pdase_M17_N2 PF18295.1 KFO99166.1 - 0.038 14.2 0.3 0.038 14.2 0.3 2.2 2 0 0 2 2 2 0 M17 aminopeptidase N-terminal domain 2 Toprim_C_rpt PF13368.6 KFO99166.1 - 4.2 7.4 4.7 4.7 7.3 0.2 2.6 2 0 0 2 2 2 0 Topoisomerase C-terminal repeat BRO1 PF03097.18 KFO99167.1 - 4.8e-95 318.6 0.1 6.3e-95 318.3 0.1 1.1 1 0 0 1 1 1 1 BRO1-like domain HR1 PF02185.16 KFO99167.1 - 1.5e-13 50.6 4.0 1.5e-13 50.6 4.0 2.3 2 0 0 2 2 2 1 Hr1 repeat PDZ_6 PF17820.1 KFO99167.1 - 1.7e-06 27.8 0.0 4.8e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFO99167.1 - 7e-05 23.1 0.0 0.00022 21.5 0.0 1.9 2 0 0 2 2 2 1 PDZ domain MutL_C PF08676.11 KFO99167.1 - 0.033 13.9 0.3 0.085 12.6 0.3 1.7 1 0 0 1 1 1 0 MutL C terminal dimerisation domain DUF1604 PF07713.13 KFO99168.1 - 2.7e-35 120.1 0.7 2.7e-35 120.1 0.7 5.0 6 0 0 6 6 6 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KFO99168.1 - 5e-07 29.5 1.8 7.9e-07 28.9 0.1 2.2 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KFO99168.1 - 0.0016 18.5 0.0 0.0016 18.5 0.0 4.2 4 1 0 4 4 4 1 G-patch domain WD40 PF00400.32 KFO99169.1 - 4.8e-38 128.5 29.0 1.4e-07 32.0 3.3 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO99169.1 - 1.4e-09 38.1 0.6 0.051 13.9 0.0 4.1 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFO99169.1 - 3e-09 36.1 4.9 0.0029 16.3 0.0 4.0 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KFO99169.1 - 1.2e-07 30.6 0.2 1.9e-06 26.7 0.2 1.9 1 1 0 1 1 1 1 Cytochrome D1 heme domain PQQ_2 PF13360.6 KFO99169.1 - 1.6e-07 31.1 0.1 3.8e-07 29.9 0.1 1.7 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.21 KFO99169.1 - 2.5e-05 24.0 0.2 0.00073 19.4 0.2 2.6 2 0 0 2 2 2 1 PQQ enzyme repeat Ge1_WD40 PF16529.5 KFO99169.1 - 3.2e-05 23.1 2.1 0.006 15.6 0.7 2.9 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFO99169.1 - 5.3e-05 23.2 0.6 0.078 12.8 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 KFO99169.1 - 0.00017 22.0 0.0 1.3 9.6 0.0 3.7 4 0 0 4 4 4 2 PQQ-like domain Hira PF07569.11 KFO99169.1 - 0.17 11.6 2.2 6.8 6.3 0.1 3.0 2 2 1 3 3 3 0 TUP1-like enhancer of split Frtz PF11768.8 KFO99169.1 - 0.24 9.7 0.8 1.3 7.3 0.2 2.1 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Ldl_recept_a PF00057.18 KFO99170.1 - 4.4e-42 142.0 83.6 7.8e-13 48.4 10.9 5.4 5 0 0 5 5 5 5 Low-density lipoprotein receptor domain class A CUB PF00431.20 KFO99170.1 - 3.1e-32 111.2 0.5 1.2e-21 77.1 0.0 2.4 2 0 0 2 2 2 2 CUB domain Syndecan PF01034.20 KFO99170.1 - 0.22 11.5 0.8 0.37 10.7 0.8 1.3 1 0 0 1 1 1 0 Syndecan domain AA_permease_2 PF13520.6 KFO99171.1 - 1.2e-60 205.6 42.9 1.5e-60 205.3 42.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFO99171.1 - 5.6e-34 117.6 36.5 6.9e-34 117.3 36.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF5408 PF17402.2 KFO99171.1 - 0.5 10.3 3.7 1.5 8.8 3.7 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5408) p53-inducible11 PF14936.6 KFO99171.1 - 0.93 9.5 12.4 2.1 8.4 2.0 2.7 2 1 0 2 2 2 0 Tumour protein p53-inducible protein 11 bZIP_2 PF07716.15 KFO99172.1 - 1.4e-15 57.1 16.9 1.9e-15 56.7 16.9 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KFO99172.1 - 2e-05 24.6 12.4 3.6e-05 23.8 12.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor DUF1319 PF07028.11 KFO99172.1 - 0.016 15.4 1.6 0.023 14.9 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) Jnk-SapK_ap_N PF09744.9 KFO99172.1 - 0.035 14.3 6.4 0.048 13.9 6.4 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 bZIP_Maf PF03131.17 KFO99172.1 - 0.044 14.3 7.7 0.077 13.5 7.7 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Seryl_tRNA_N PF02403.22 KFO99172.1 - 0.048 13.9 6.9 0.079 13.2 6.9 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 KFO99172.1 - 0.12 12.9 6.9 0.18 12.3 6.9 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region XhlA PF10779.9 KFO99172.1 - 0.19 11.9 6.4 0.19 12.0 5.2 1.6 1 1 0 1 1 1 0 Haemolysin XhlA DUF4094 PF13334.6 KFO99172.1 - 0.34 11.3 3.2 0.52 10.8 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DivIC PF04977.15 KFO99172.1 - 0.38 10.6 7.7 0.38 10.5 6.5 1.6 1 1 0 1 1 1 0 Septum formation initiator Tho2 PF11262.8 KFO99172.1 - 0.93 8.6 6.0 1.1 8.3 6.0 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 LAM_C PF12544.8 KFO99172.1 - 1.8 8.8 6.6 11 6.1 6.6 2.2 1 1 0 1 1 1 0 Lysine-2,3-aminomutase Peptidase_M24 PF00557.24 KFO99173.1 - 1e-61 208.3 0.0 8.9e-59 198.7 0.1 3.0 3 0 0 3 3 3 3 Metallopeptidase family M24 AMP_N PF05195.16 KFO99173.1 - 6.2e-28 97.0 0.0 1.4e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Sulfotransfer_2 PF03567.14 KFO99174.1 - 9e-57 192.9 3.8 1.1e-56 192.6 3.8 1.1 1 0 0 1 1 1 1 Sulfotransferase family BTB_2 PF02214.22 KFO99175.1 - 9.5e-17 61.1 0.1 1.5e-16 60.5 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain TAF4 PF05236.14 KFO99176.1 - 1.3e-76 258.0 7.3 1.5e-76 257.8 7.3 1.0 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TAF PF02969.17 KFO99176.1 - 5.7e-05 23.2 0.4 0.36 11.0 0.1 2.5 2 0 0 2 2 2 2 TATA box binding protein associated factor (TAF) Presenilin PF01080.17 KFO99176.1 - 0.032 13.0 1.4 0.042 12.6 1.4 1.1 1 0 0 1 1 1 0 Presenilin DUF1955 PF09205.10 KFO99176.1 - 0.14 11.9 0.3 0.22 11.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) LSM14 PF12701.7 KFO99177.1 - 1.5e-33 114.7 0.0 2.7e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KFO99177.1 - 5e-31 107.7 7.8 5e-31 107.7 7.8 2.1 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.6 KFO99177.1 - 5.5e-08 32.8 0.0 1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain GRP PF07172.11 KFO99177.1 - 6.1 7.6 18.6 20 5.9 12.0 2.6 2 0 0 2 2 2 0 Glycine rich protein family TINF2_N PF14973.6 KFO99178.1 - 0.069 13.5 0.0 0.1 13.0 0.0 1.3 1 1 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus PGI PF00342.19 KFO99179.1 - 8.7e-263 872.2 0.0 9.9e-263 872.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF4473 PF14747.6 KFO99179.1 - 0.012 16.2 0.1 0.045 14.3 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) LIM PF00412.22 KFO99180.1 - 1.3e-36 124.6 37.2 4e-14 52.6 8.4 3.1 3 0 0 3 3 3 3 LIM domain Mut7-C PF01927.16 KFO99180.1 - 0.062 13.4 1.6 0.062 13.4 1.6 3.2 1 1 3 4 4 4 0 Mut7-C RNAse domain ThiF PF00899.21 KFO99181.1 - 7e-57 192.6 0.0 1.1e-56 192.0 0.0 1.3 1 0 0 1 1 1 1 ThiF family UBA2_C PF16195.5 KFO99181.1 - 7.6e-25 87.4 10.6 7.6e-25 87.4 10.6 2.1 2 0 0 2 2 2 1 SUMO-activating enzyme subunit 2 C-terminus UAE_UbL PF14732.6 KFO99181.1 - 1.1e-22 80.4 1.1 1.1e-22 80.4 1.1 2.0 3 0 0 3 3 3 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 KFO99181.1 - 3.1e-06 27.3 8.5 0.0029 17.6 0.5 2.7 2 1 1 3 3 3 2 Ubiquitin-activating enzyme active site PDCD2_C PF04194.13 KFO99182.1 - 1.9e-46 158.4 0.2 2.5e-46 157.9 0.2 1.2 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain COesterase PF00135.28 KFO99183.1 - 7.1e-167 556.4 0.0 7.9e-167 556.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFO99183.1 - 2.4e-10 40.6 1.6 7.2e-10 39.1 1.6 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFO99183.1 - 0.0012 18.4 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KFO99183.1 - 0.012 16.3 0.2 0.024 15.2 0.2 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 KFO99183.1 - 0.16 10.8 0.0 0.3 9.9 0.0 1.4 1 0 0 1 1 1 0 Steryl acetyl hydrolase FeS_assembly_P PF01883.19 KFO99184.1 - 7.2e-15 54.9 0.1 1.6e-14 53.8 0.0 1.6 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein Ras PF00071.22 KFO99185.1 - 5.6e-32 110.6 0.0 7.7e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO99185.1 - 2.1e-10 40.8 0.0 3.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KFO99185.1 - 0.00057 19.8 0.1 0.44 10.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KFO99185.1 - 0.0007 19.2 0.1 0.0075 15.8 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 KFO99185.1 - 0.0016 17.9 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.6 KFO99185.1 - 0.0023 18.2 0.4 2.3 8.5 0.0 3.0 1 1 2 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 KFO99185.1 - 0.011 15.8 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 KFO99185.1 - 0.018 15.6 0.7 0.052 14.1 0.7 1.8 1 1 0 1 1 1 0 ABC transporter AAA PF00004.29 KFO99185.1 - 0.021 15.3 0.3 0.21 12.0 0.3 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KFO99185.1 - 0.025 15.1 0.2 0.061 13.9 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFO99185.1 - 0.05 14.0 1.2 0.3 11.4 1.3 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KFO99185.1 - 0.061 13.1 0.1 0.17 11.6 0.0 1.6 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KFO99185.1 - 0.084 12.9 0.2 0.26 11.3 0.2 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) HA1 PF18239.1 KFO99185.1 - 0.16 11.8 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Hemagglutinin I PP2C PF00481.21 KFO99186.1 - 2.2e-39 135.7 0.0 2.1e-36 125.9 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Carb_anhydrase PF00194.21 KFO99187.1 - 3.1e-99 331.6 0.0 3.5e-99 331.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF2415 PF10313.9 KFO99187.1 - 0.18 11.8 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) ThiF PF00899.21 KFO99188.1 - 1.5e-20 73.6 0.0 4.9e-20 71.9 0.0 1.9 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 KFO99188.1 - 2.7e-05 24.3 0.0 0.035 14.3 0.0 3.4 3 0 0 3 3 3 2 Ubiquitin-activating enzyme E1 four-helix bundle Transket_pyr PF02779.24 KFO99188.1 - 0.029 14.0 0.3 0.063 12.9 0.3 1.5 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain Atx10homo_assoc PF09759.9 KFO99189.1 - 1.5e-05 25.0 8.9 0.00018 21.5 1.2 3.9 3 2 1 4 4 4 2 Spinocerebellar ataxia type 10 protein domain Drf_GBD PF06371.13 KFO99189.1 - 0.049 13.2 0.3 0.049 13.2 0.3 2.0 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain RTTN_N PF14726.6 KFO99189.1 - 0.073 13.9 0.2 14 6.6 0.0 3.1 2 1 1 3 3 3 0 Rotatin, an armadillo repeat protein, centriole functioning RICTOR_V PF14668.6 KFO99189.1 - 0.15 12.3 1.2 2 8.7 0.2 2.6 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 DLIC PF05783.11 KFO99191.1 - 2.4e-253 841.1 0.0 2.8e-253 840.9 0.0 1.0 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) ABC_tran PF00005.27 KFO99191.1 - 0.0019 18.7 0.0 0.0036 17.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Roc PF08477.13 KFO99191.1 - 0.0091 16.2 0.2 0.043 14.0 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 KFO99191.1 - 0.022 14.7 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 KFO99191.1 - 0.028 14.2 0.2 0.063 13.0 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arf PF00025.21 KFO99191.1 - 0.035 13.6 0.2 0.46 9.9 0.0 2.5 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA_16 PF13191.6 KFO99191.1 - 0.035 14.5 0.1 0.072 13.5 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KFO99191.1 - 0.036 14.0 0.2 8.8 6.2 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 KFO99191.1 - 0.038 14.3 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KFO99191.1 - 0.04 13.5 0.1 9.3 5.7 0.1 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 KFO99191.1 - 0.044 13.5 0.1 0.16 11.7 0.1 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 KFO99191.1 - 0.047 13.4 0.1 0.085 12.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain Kinesin PF00225.23 KFO99191.1 - 0.099 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain ATPase PF06745.13 KFO99191.1 - 0.13 11.6 0.1 0.25 10.6 0.2 1.5 1 1 0 1 1 1 0 KaiC AAA_23 PF13476.6 KFO99191.1 - 0.15 12.5 0.0 0.31 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KFO99191.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit SRP54 PF00448.22 KFO99191.1 - 0.26 10.9 1.0 0.73 9.4 0.4 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MARVEL PF01284.23 KFO99192.1 - 7e-14 52.1 14.8 1e-13 51.5 14.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain YfhO PF09586.10 KFO99192.1 - 0.00023 19.6 0.6 0.00026 19.4 0.6 1.0 1 0 0 1 1 1 1 Bacterial membrane protein YfhO Ni_hydr_CYTB PF01292.20 KFO99192.1 - 0.016 14.8 0.2 0.022 14.4 0.2 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 YIF1 PF03878.15 KFO99192.1 - 0.23 11.0 4.9 0.37 10.3 4.8 1.3 1 1 0 1 1 1 0 YIF1 DUF373 PF04123.13 KFO99192.1 - 0.71 9.3 4.0 2.1 7.7 4.4 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF373) MARVEL PF01284.23 KFO99193.1 - 4.2e-09 36.6 18.4 7.4e-09 35.8 18.4 1.4 1 1 0 1 1 1 1 Membrane-associating domain STE PF02200.16 KFO99193.1 - 0.21 12.0 1.3 19 5.7 0.2 2.4 1 1 2 3 3 3 0 STE like transcription factor CbiQ PF02361.16 KFO99193.1 - 5 6.7 8.1 6.2 6.4 8.1 1.2 1 0 0 1 1 1 0 Cobalt transport protein MARVEL PF01284.23 KFO99194.1 - 9.7e-07 28.9 16.9 2.8e-06 27.4 16.9 1.7 1 1 0 1 1 1 1 Membrane-associating domain Herpes_LMP1 PF05297.11 KFO99194.1 - 0.39 9.8 12.5 0.46 9.6 12.5 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF3043 PF11241.8 KFO99194.1 - 3.6 7.6 8.5 1.3 9.0 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) DUF543 PF04418.12 KFO99194.1 - 5 7.2 5.5 1.1 9.3 1.7 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF543) DUF3792 PF12670.7 KFO99194.1 - 8.9 6.5 20.3 2.2 8.5 14.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3792) DUF5090 PF17009.5 KFO99194.1 - 9.6 6.1 12.2 12 5.8 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) dNK PF01712.19 KFO99195.1 - 1.5e-25 90.2 0.8 1.8e-25 90.0 0.8 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 KFO99195.1 - 0.00057 20.4 0.0 0.00081 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFO99195.1 - 0.00089 19.4 0.0 0.0014 18.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KFO99195.1 - 0.0024 17.6 0.1 0.003 17.2 0.0 1.3 1 1 0 1 1 1 1 Thymidylate kinase AAA_17 PF13207.6 KFO99195.1 - 0.0093 16.4 0.1 0.016 15.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain PUB PF09409.10 KFO99196.1 - 0.0052 16.7 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 PUB domain Herpes_UL56 PF04534.12 KFO99197.1 - 0.0056 16.2 0.3 0.009 15.5 0.3 1.2 1 0 0 1 1 1 1 Herpesvirus UL56 protein CYYR1 PF10873.8 KFO99197.1 - 0.31 11.5 4.2 1.9 8.9 1.4 2.1 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 Cadherin PF00028.17 KFO99198.1 - 3.1e-67 223.0 9.9 1.4e-19 70.3 0.7 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFO99198.1 - 1.1e-43 149.0 0.4 2e-43 148.2 0.4 1.4 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_3 PF16184.5 KFO99198.1 - 4.6e-05 23.4 4.7 4.8 7.2 0.0 4.7 5 0 0 5 5 5 3 Cadherin-like Cadherin_pro PF08758.11 KFO99198.1 - 0.0023 18.0 0.3 2.2 8.5 0.0 3.2 3 0 0 3 3 3 2 Cadherin prodomain like Cadherin_2 PF08266.12 KFO99198.1 - 0.15 11.9 0.2 2.4 8.0 0.0 3.0 4 0 0 4 4 4 0 Cadherin-like Cadherin PF00028.17 KFO99199.1 - 4.2e-82 270.7 5.4 5.1e-19 68.5 0.0 5.4 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFO99199.1 - 2.2e-57 193.4 0.1 4.3e-57 192.5 0.1 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_3 PF16184.5 KFO99199.1 - 4.4e-07 29.9 5.3 1.2 9.1 0.0 5.7 6 0 0 6 6 6 2 Cadherin-like Cadherin_2 PF08266.12 KFO99199.1 - 7.9e-05 22.4 0.0 0.13 12.1 0.0 3.6 3 0 0 3 3 3 1 Cadherin-like Cadherin_pro PF08758.11 KFO99199.1 - 0.0015 18.6 0.0 1.2 9.4 0.0 3.5 3 0 0 3 3 3 1 Cadherin prodomain like ASFV_J13L PF05568.11 KFO99199.1 - 0.019 14.7 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Invasin_D3 PF09134.10 KFO99199.1 - 0.044 14.1 2.8 15 6.0 0.0 4.7 4 1 1 5 5 5 0 Invasin, domain 3 DUF4286 PF14114.6 KFO99199.1 - 0.099 13.1 0.0 0.43 11.1 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) Cadherin_4 PF17803.1 KFO99199.1 - 0.62 10.7 14.1 3.8 8.2 0.2 4.7 5 0 0 5 5 5 0 Bacterial cadherin-like domain Cadherin PF00028.17 KFO99200.1 - 3.2e-85 280.7 1.0 8.5e-18 64.6 0.0 5.2 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFO99200.1 - 5e-18 65.8 0.2 1.2e-17 64.6 0.2 1.7 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_4 PF17803.1 KFO99200.1 - 6.9e-08 33.0 12.7 0.0014 19.2 0.6 4.1 4 0 0 4 4 4 2 Bacterial cadherin-like domain Cadherin_2 PF08266.12 KFO99200.1 - 1.2e-05 25.1 0.0 0.65 9.9 0.0 3.9 4 0 0 4 4 4 2 Cadherin-like Cadherin_3 PF16184.5 KFO99200.1 - 3.6e-05 23.7 5.0 2.6 8.1 0.1 5.2 5 0 0 5 5 5 2 Cadherin-like Big_9 PF17963.1 KFO99200.1 - 0.0093 16.7 10.2 1.7 9.4 0.2 3.9 3 0 0 3 3 3 2 Bacterial Ig domain Cadherin_pro PF08758.11 KFO99200.1 - 0.018 15.2 0.0 2 8.6 0.0 2.8 2 0 0 2 2 2 0 Cadherin prodomain like Invasin_D3 PF09134.10 KFO99200.1 - 0.13 12.6 0.9 3.9 7.8 0.0 3.4 3 1 0 3 3 3 0 Invasin, domain 3 DUF5527 PF17665.1 KFO99200.1 - 0.54 9.8 2.2 1 8.9 2.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5527) RVT_1 PF00078.27 KFO99202.1 - 0.12 11.9 0.0 0.31 10.5 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pep_M12B_propep PF01562.19 KFO99203.1 - 1.9e-36 125.4 0.9 3.6e-36 124.5 0.9 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_spacer1 PF05986.14 KFO99203.1 - 4.6e-34 116.9 0.0 9.3e-34 115.9 0.0 1.5 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.19 KFO99203.1 - 1.5e-30 105.2 84.2 7.1e-11 42.2 8.9 7.9 6 1 0 6 6 6 6 Thrombospondin type 1 domain Reprolysin PF01421.19 KFO99203.1 - 1.1e-28 100.5 0.1 2.2e-28 99.5 0.1 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 KFO99203.1 - 4.8e-20 71.9 8.3 4.8e-20 71.9 8.3 6.4 6 2 1 7 7 7 2 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 KFO99203.1 - 9.9e-11 42.2 1.2 1.6e-10 41.5 0.1 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12 PLAC PF08686.11 KFO99203.1 - 1.1e-10 42.1 8.8 1.1e-10 42.1 8.8 5.1 4 0 0 4 4 4 1 PLAC (protease and lacunin) domain Reprolysin_2 PF13574.6 KFO99203.1 - 1.7e-09 37.9 0.1 3.5e-09 36.9 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 KFO99203.1 - 1e-06 29.2 0.1 3.1e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFO99203.1 - 0.00043 20.0 0.1 0.00093 18.9 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pribosyltran PF00156.27 KFO99204.1 - 0.006 16.1 0.0 0.0075 15.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NUDIX PF00293.28 KFO99205.1 - 5.2e-12 46.0 0.0 8.1e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain ADH_zinc_N_2 PF13602.6 KFO99206.1 - 5.6e-14 53.3 0.0 1.4e-13 52.1 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFO99206.1 - 6.2e-10 39.2 0.0 1.3e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFO99206.1 - 5.1e-08 32.8 0.0 1.1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Lectin_C PF00059.21 KFO99207.1 - 3.1e-19 69.7 0.1 4.9e-19 69.1 0.1 1.3 1 0 0 1 1 1 1 Lectin C-type domain Chordopox_A33R PF05966.12 KFO99207.1 - 0.014 14.7 0.1 0.019 14.3 0.1 1.2 1 0 0 1 1 1 0 Chordopoxvirus A33R protein GPS PF01825.21 KFO99207.1 - 0.031 14.8 0.6 0.086 13.4 0.6 1.8 1 0 0 1 1 1 0 GPCR proteolysis site, GPS, motif adh_short PF00106.25 KFO99208.1 - 2.3e-27 95.8 0.0 8.9e-23 80.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase WW PF00397.26 KFO99208.1 - 5.4e-18 64.8 11.3 1.1e-09 38.2 5.0 2.5 2 0 0 2 2 2 2 WW domain adh_short_C2 PF13561.6 KFO99208.1 - 5.3e-16 58.9 0.1 4.1e-14 52.7 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFO99208.1 - 1.5e-08 34.8 0.1 2.2e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFO99208.1 - 0.0076 15.7 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KFO99208.1 - 0.025 14.8 0.0 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain PerB PF06590.11 KFO99208.1 - 0.12 12.9 0.0 0.31 11.5 0.0 1.7 1 0 0 1 1 1 0 PerB protein bZIP_Maf PF03131.17 KFO99209.1 - 2.5e-23 82.4 10.7 4.5e-23 81.6 10.7 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Maf_N PF08383.11 KFO99209.1 - 1.7e-19 69.2 0.5 3.1e-19 68.4 0.5 1.3 1 0 0 1 1 1 1 Maf N-terminal region ZapB PF06005.12 KFO99209.1 - 0.00078 19.8 11.8 0.014 15.8 5.1 2.2 1 1 1 2 2 2 2 Cell division protein ZapB bZIP_1 PF00170.21 KFO99209.1 - 0.0061 16.6 12.1 0.008 16.2 11.4 1.6 1 1 0 1 1 1 1 bZIP transcription factor APC_N_CC PF16689.5 KFO99209.1 - 0.011 15.8 5.9 0.013 15.5 1.4 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain DUF1192 PF06698.11 KFO99209.1 - 0.011 15.8 3.7 0.96 9.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) KASH_CCD PF14662.6 KFO99209.1 - 0.012 15.4 9.7 0.033 14.0 9.7 1.7 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 KFO99209.1 - 0.014 14.8 7.1 0.024 14.0 7.1 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding bZIP_2 PF07716.15 KFO99209.1 - 0.015 15.4 9.2 0.021 14.9 7.2 2.1 1 1 1 2 2 2 0 Basic region leucine zipper HOOK PF05622.12 KFO99209.1 - 0.02 13.1 3.9 0.027 12.7 3.9 1.1 1 0 0 1 1 1 0 HOOK protein JIP_LZII PF16471.5 KFO99209.1 - 0.022 14.9 6.2 0.082 13.1 2.2 2.2 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II vATP-synt_E PF01991.18 KFO99209.1 - 0.035 13.5 4.8 0.049 13.0 4.8 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit STAT_alpha PF01017.20 KFO99209.1 - 0.037 13.9 4.9 0.053 13.4 4.9 1.1 1 0 0 1 1 1 0 STAT protein, all-alpha domain JAKMIP_CC3 PF16034.5 KFO99209.1 - 0.051 13.5 6.3 0.077 12.9 6.3 1.2 1 0 0 1 1 1 0 JAKMIP CC3 domain Seryl_tRNA_N PF02403.22 KFO99209.1 - 0.059 13.6 5.4 0.09 13.0 5.4 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain UBA PF00627.31 KFO99209.1 - 0.13 12.2 0.0 3.6 7.6 0.0 2.5 2 0 0 2 2 2 0 UBA/TS-N domain DUF2353 PF09789.9 KFO99209.1 - 0.2 11.0 8.2 0.28 10.5 8.2 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Spc24 PF08286.11 KFO99209.1 - 0.22 11.8 1.9 0.8 10.0 0.5 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF5320 PF17253.2 KFO99209.1 - 0.28 12.3 2.9 12 7.0 2.3 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5320) FapA PF03961.13 KFO99209.1 - 0.29 9.7 2.5 0.39 9.3 2.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1635 PF07795.11 KFO99209.1 - 0.51 10.1 4.3 0.36 10.7 1.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1635) Cnn_1N PF07989.11 KFO99209.1 - 0.68 10.1 7.7 8.7 6.6 3.3 2.2 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 MbeD_MobD PF04899.12 KFO99209.1 - 0.72 10.0 5.0 3.2 7.9 5.1 2.0 1 1 1 2 2 2 0 MbeD/MobD like TSC22 PF01166.18 KFO99209.1 - 1.3 9.4 5.7 10 6.5 0.4 2.5 1 1 0 2 2 2 0 TSC-22/dip/bun family DivIC PF04977.15 KFO99209.1 - 1.8 8.4 11.0 1.3 8.8 4.1 2.2 1 1 1 2 2 2 0 Septum formation initiator APG6_N PF17675.1 KFO99209.1 - 2.6 8.6 9.9 16 6.0 9.9 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region Osmo_CC PF08946.10 KFO99209.1 - 2.7 8.3 7.8 8.1 6.8 0.5 2.3 2 0 0 2 2 2 0 Osmosensory transporter coiled coil GIT_CC PF16559.5 KFO99209.1 - 2.8 7.9 6.8 2.1 8.3 1.2 2.7 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2205 PF10224.9 KFO99209.1 - 4.3 7.4 8.2 1.1 9.3 2.1 2.2 2 0 0 2 2 2 0 Short coiled-coil protein CENP-Q PF13094.6 KFO99209.1 - 4.5 7.4 9.2 1.3 9.2 5.7 1.7 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit UPF0449 PF15136.6 KFO99209.1 - 4.8 7.7 6.7 13 6.3 6.1 2.0 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 Robl_LC7 PF03259.17 KFO99210.1 - 1.7e-16 59.8 0.0 1.8e-16 59.7 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain ECH_1 PF00378.20 KFO99211.1 - 1.3e-28 100.0 0.0 1.8e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Chromo PF00385.24 KFO99211.1 - 1.8e-16 59.8 1.9 3.5e-16 58.8 1.9 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ECH_2 PF16113.5 KFO99211.1 - 2.4e-12 47.0 0.0 3.4e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Mtf2_C PF14061.6 KFO99211.1 - 0.04 14.1 0.8 0.086 13.0 0.8 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Cmc1 PF08583.10 KFO99212.1 - 9.7e-17 60.8 3.9 1.1e-16 60.6 3.9 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF755 PF05501.11 KFO99212.1 - 0.033 14.5 0.5 0.037 14.3 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) CENP-N PF05238.13 KFO99213.1 - 2.9e-66 224.5 3.4 8.4e-65 219.7 3.4 2.0 1 1 0 1 1 1 1 Kinetochore protein CHL4 like zf-C2H2 PF00096.26 KFO99214.1 - 5.3e-05 23.5 16.3 1.2 9.8 0.3 5.6 3 1 1 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO99214.1 - 0.004 17.9 15.0 2.5 9.2 0.5 5.3 3 1 1 4 4 4 2 C2H2-type zinc finger FOXP-CC PF16159.5 KFO99214.1 - 0.019 15.6 0.3 0.13 12.9 0.0 2.5 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KFO99214.1 - 4.4 7.4 12.0 5.2 7.2 1.1 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger GCV_H PF01597.19 KFO99215.1 - 5.6e-43 145.7 0.0 6.1e-43 145.6 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein RPE65 PF03055.15 KFO99216.1 - 3.1e-122 409.1 2.4 3.4e-122 408.9 2.4 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Kelch_1 PF01344.25 KFO99217.1 - 2.5e-39 132.6 2.7 1.3e-09 37.4 0.0 6.4 6 1 0 6 6 6 4 Kelch motif BACK PF07707.15 KFO99217.1 - 3.9e-29 100.8 0.8 9.5e-29 99.5 0.2 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFO99217.1 - 9.8e-22 76.5 10.0 1.7e-08 34.5 0.0 6.1 4 2 3 7 7 7 3 Kelch motif Kelch_4 PF13418.6 KFO99217.1 - 6.6e-14 51.7 4.6 1.3e-05 25.1 0.0 5.4 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 KFO99217.1 - 9.1e-14 50.8 0.8 0.036 14.0 0.0 5.9 6 0 0 6 6 6 4 Kelch motif BTB PF00651.31 KFO99217.1 - 9.6e-10 38.7 0.0 2.2e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.6 KFO99217.1 - 1.5e-09 37.9 0.2 0.019 15.3 0.0 5.6 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KFO99217.1 - 1.5e-07 31.2 4.6 0.025 14.6 0.0 4.8 5 0 0 5 5 5 2 Kelch motif DUF1668 PF07893.13 KFO99217.1 - 0.0062 15.9 0.0 0.7 9.2 0.0 2.5 1 1 0 2 2 2 1 Protein of unknown function (DUF1668) BTB_3 PF16017.5 KFO99217.1 - 0.083 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain LRR_4 PF12799.7 KFO99218.1 - 6.9e-06 26.3 10.2 0.0083 16.5 0.2 4.5 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFO99218.1 - 2.9e-05 23.8 2.2 0.12 12.1 0.2 3.1 2 0 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 KFO99218.1 - 0.0042 17.0 1.1 5.1 7.4 0.0 4.4 4 0 0 4 4 4 2 Leucine Rich repeat PH PF00169.29 KFO99218.1 - 0.041 14.4 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 PH domain PI-PLC-X PF00388.19 KFO99220.1 - 1.4e-66 222.6 0.1 3.3e-66 221.3 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain SH2 PF00017.24 KFO99220.1 - 2.3e-47 159.0 0.6 1.6e-25 89.0 0.1 2.9 2 0 0 2 2 2 2 SH2 domain PI-PLC-Y PF00387.19 KFO99220.1 - 5.6e-38 129.8 0.1 2.3e-37 127.8 0.0 2.2 2 0 0 2 2 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KFO99220.1 - 9.9e-15 54.7 0.0 3.5e-14 52.9 0.0 2.0 1 0 0 1 1 1 1 C2 domain SH3_1 PF00018.28 KFO99220.1 - 4.1e-13 48.7 0.1 1.3e-12 47.1 0.1 2.0 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFO99220.1 - 5.2e-11 42.2 0.1 2.1e-10 40.3 0.1 2.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFO99220.1 - 2.5e-06 27.0 0.0 7e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 KFO99220.1 - 1.2e-05 25.8 5.2 0.7 10.4 0.0 4.6 4 0 0 4 4 4 3 PH domain PH_12 PF16457.5 KFO99220.1 - 2.5e-05 24.8 0.5 0.00021 21.8 0.0 2.8 3 0 0 3 3 3 1 Pleckstrin homology domain EF-hand_like PF09279.11 KFO99220.1 - 0.014 15.9 0.5 0.052 14.0 0.4 2.2 1 1 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like PH_14 PF17787.1 KFO99220.1 - 0.035 14.0 0.1 0.11 12.4 0.1 1.9 1 0 0 1 1 1 0 PH domain 3Beta_HSD PF01073.19 KFO99221.1 - 5.1e-71 238.9 0.0 6.6e-71 238.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFO99221.1 - 7.4e-26 91.1 0.0 9.3e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFO99221.1 - 6.4e-12 45.2 0.0 8.8e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KFO99221.1 - 8.9e-10 38.5 0.0 5.1e-08 32.7 0.0 2.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KFO99221.1 - 8.5e-08 31.7 0.1 2.5e-07 30.1 0.0 1.9 1 1 1 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 KFO99221.1 - 6.1e-07 28.9 0.5 2.3e-06 27.0 0.5 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KFO99221.1 - 0.00016 21.6 0.0 0.00022 21.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KFO99222.1 - 2.1e-42 144.8 0.0 2.5e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFO99222.1 - 5.7e-29 101.3 0.0 7.5e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFO99222.1 - 1.3e-05 25.2 0.0 1.8e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFO99222.1 - 0.00042 19.8 0.0 0.00086 18.8 0.0 1.4 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) LytR_C PF13399.6 KFO99222.1 - 0.18 12.8 0.3 3.2 8.8 0.1 2.3 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator Acetyltransf_2 PF00797.17 KFO99223.1 - 3.7e-91 305.2 0.1 4.2e-91 305.0 0.1 1.0 1 0 0 1 1 1 1 N-acetyltransferase Acetyltransf_2 PF00797.17 KFO99224.1 - 4.3e-89 298.4 0.1 4.9e-89 298.2 0.1 1.0 1 0 0 1 1 1 1 N-acetyltransferase Acetyltransf_2 PF00797.17 KFO99225.1 - 7.1e-93 310.8 1.0 8.2e-93 310.6 1.0 1.0 1 0 0 1 1 1 1 N-acetyltransferase MPP6 PF10175.9 KFO99226.1 - 1.3e-35 122.8 5.9 2.1e-35 122.1 5.9 1.3 1 0 0 1 1 1 1 M-phase phosphoprotein 6 DUF3864 PF12980.7 KFO99226.1 - 0.062 13.6 0.1 0.19 12.1 0.0 1.9 2 1 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3864) Cadherin PF00028.17 KFO99227.1 - 8.2e-70 231.3 4.1 5.4e-20 71.6 0.0 4.6 5 0 0 5 5 5 4 Cadherin domain Cadherin_3 PF16184.5 KFO99227.1 - 1.1e-10 41.5 3.4 0.016 15.2 0.2 5.3 5 0 0 5 5 5 4 Cadherin-like Cadherin_4 PF17803.1 KFO99227.1 - 8.4e-05 23.1 18.8 0.00011 22.7 3.4 3.9 4 0 0 4 4 4 2 Bacterial cadherin-like domain Big_9 PF17963.1 KFO99227.1 - 0.00012 22.8 5.2 0.00012 22.8 5.2 3.2 2 1 1 3 3 3 1 Bacterial Ig domain MCD PF05292.11 KFO99228.1 - 7.7e-23 81.4 0.1 1.1e-22 80.9 0.1 1.2 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain HSBP1 PF06825.12 KFO99231.1 - 2e-19 69.1 3.1 2.9e-19 68.7 3.1 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.9 KFO99231.1 - 0.032 14.1 0.1 0.049 13.5 0.1 1.4 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin UPF0184 PF03670.13 KFO99231.1 - 0.045 14.2 0.3 0.048 14.0 0.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Serine_rich PF08824.10 KFO99231.1 - 0.051 13.6 0.2 0.051 13.6 0.2 1.1 1 0 0 1 1 1 0 Serine rich protein interaction domain Ion_trans PF00520.31 KFO99232.1 - 3.8e-38 131.1 3.4 5.1e-38 130.7 3.4 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFO99232.1 - 9.9e-25 86.7 0.0 2.3e-24 85.5 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFO99232.1 - 1.8e-12 47.0 4.8 2e-12 46.9 2.5 2.2 2 0 0 2 2 2 1 Ion channel Latarcin PF10279.9 KFO99232.1 - 0.046 14.1 0.2 21 5.6 1.0 2.6 2 0 0 2 2 2 0 Latarcin precursor WAP PF00095.21 KFO99233.1 - 2e-06 28.1 15.1 2e-06 28.1 15.1 2.1 2 0 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' E1-E2_ATPase PF00122.20 KFO99234.1 - 5.1e-51 172.8 0.1 5.1e-51 172.8 0.1 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFO99234.1 - 1.5e-43 148.7 5.5 1.5e-43 148.7 5.5 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 KFO99234.1 - 1.3e-18 66.5 0.1 2.9e-18 65.3 0.1 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KFO99234.1 - 7e-17 62.4 5.6 4e-16 59.9 5.6 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFO99234.1 - 3.8e-15 55.7 0.1 1e-14 54.3 0.1 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFO99234.1 - 0.00047 20.0 3.3 0.00047 20.0 3.3 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3784 PF12650.7 KFO99234.1 - 0.38 11.0 6.6 12 6.2 0.3 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) TLD PF07534.16 KFO99235.1 - 3.1e-38 131.1 0.2 4.6e-38 130.6 0.2 1.3 1 0 0 1 1 1 1 TLD Cofilin_ADF PF00241.20 KFO99236.1 - 1.9e-20 72.9 0.0 2.2e-20 72.7 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Kelch_1 PF01344.25 KFO99237.1 - 5e-42 141.3 11.3 1.1e-09 37.7 0.1 6.3 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KFO99237.1 - 1.4e-31 107.7 4.2 8.1e-05 22.8 0.1 6.5 4 2 2 6 6 6 6 Kelch motif BTB PF00651.31 KFO99237.1 - 6.5e-28 97.2 0.8 3.5e-27 94.8 0.0 2.5 2 1 1 3 3 3 1 BTB/POZ domain Kelch_2 PF07646.15 KFO99237.1 - 6.2e-22 76.7 5.4 0.00036 20.4 0.2 6.6 6 0 0 6 6 6 4 Kelch motif BACK PF07707.15 KFO99237.1 - 2.3e-21 75.8 0.3 4.5e-21 74.9 0.3 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 KFO99237.1 - 2.2e-20 72.4 2.5 0.004 17.1 0.1 5.6 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KFO99237.1 - 1.2e-14 54.2 1.3 0.31 11.4 0.2 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFO99237.1 - 1.8e-13 50.2 2.7 1.3e-05 25.1 0.1 5.1 5 0 0 5 5 5 3 Kelch motif UCH PF00443.29 KFO99238.1 - 1.5e-38 132.8 0.0 2.3e-38 132.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFO99238.1 - 1.7e-07 31.2 0.0 2.6e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PAM2 PF07145.15 KFO99238.1 - 3.2e-05 23.3 0.0 9.5e-05 21.8 0.0 1.9 1 0 0 1 1 1 1 Ataxin-2 C-terminal region LCCL PF03815.19 KFO99239.1 - 6e-51 170.5 9.8 3.9e-27 94.2 0.1 3.0 3 0 0 3 3 3 2 LCCL domain CAP PF00188.26 KFO99239.1 - 3.4e-21 76.4 4.2 6e-21 75.6 4.2 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Rxt3 PF08642.10 KFO99239.1 - 9.4e-06 26.4 0.0 0.0025 18.6 0.0 2.7 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 DUF5607 PF18355.1 KFO99239.1 - 0.029 14.8 0.0 0.069 13.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5607) zf-C4 PF00105.18 KFO99240.1 - 8.9e-32 109.4 18.1 9.9e-32 109.2 18.1 1.0 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Ank_2 PF12796.7 KFO99241.1 - 3.7e-64 213.3 27.9 3.5e-18 66.0 2.8 4.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFO99241.1 - 1.7e-43 146.4 15.2 2.3e-09 37.6 0.2 6.0 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFO99241.1 - 2.3e-39 132.9 20.0 8.7e-11 41.9 0.1 8.2 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFO99241.1 - 2.6e-34 113.4 10.2 4.1e-05 23.7 0.1 8.5 8 0 0 8 8 8 8 Ankyrin repeat Ank PF00023.30 KFO99241.1 - 6.8e-33 111.7 18.2 5.3e-09 36.1 0.2 9.2 9 0 0 9 9 9 7 Ankyrin repeat Death PF00531.22 KFO99241.1 - 1.5e-06 28.2 0.1 3.6e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Death domain PH PF00169.29 KFO99242.1 - 7.7e-12 45.6 0.7 1.3e-11 44.9 0.7 1.4 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KFO99242.1 - 0.0011 19.3 0.3 0.068 13.5 0.3 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFO99242.1 - 0.0038 17.6 0.5 0.013 15.9 0.5 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.7 KFO99242.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Peptidase_S8 PF00082.22 KFO99243.1 - 1.9e-48 165.3 0.2 2.8e-48 164.7 0.2 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KFO99243.1 - 3.5e-31 107.1 0.1 5.7e-31 106.4 0.1 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KFO99243.1 - 4.8e-14 52.9 1.1 2.2e-13 50.8 1.4 2.0 2 0 0 2 2 2 1 Peptidase S8 pro-domain Furin-like_2 PF15913.5 KFO99243.1 - 1.3e-11 44.6 62.1 8.9e-07 29.0 17.4 4.1 2 2 1 3 3 3 3 Furin-like repeat, cysteine-rich GF_recep_IV PF14843.6 KFO99243.1 - 3.7e-09 36.5 75.6 1.7e-06 27.9 13.0 3.8 1 1 2 3 3 3 2 Growth factor receptor domain IV PLAC PF08686.11 KFO99243.1 - 1.5e-06 28.8 10.1 1.5e-06 28.8 10.1 3.1 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain VSP PF03302.13 KFO99243.1 - 6.9 5.4 57.7 0.16 10.8 11.0 3.8 1 1 0 3 3 3 0 Giardia variant-specific surface protein LRR_9 PF14580.6 KFO99244.1 - 1.6e-78 262.2 1.0 2.1e-78 261.8 1.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KFO99244.1 - 3.9e-08 33.5 7.0 0.00022 21.5 1.5 2.6 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFO99244.1 - 9.3e-07 28.5 3.0 5.3e-06 26.1 2.3 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 KFO99244.1 - 9.7 6.5 5.9 8 6.8 0.1 3.4 4 0 0 4 4 4 0 Leucine Rich repeat Selenoprotein_S PF06936.11 KFO99245.1 - 1.7e-63 214.0 9.6 1.8e-63 213.8 9.6 1.0 1 0 0 1 1 1 1 Selenoprotein S (SelS) Glyco_hydro_10 PF00331.20 KFO99245.1 - 0.073 12.2 0.1 0.082 12.0 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 Trp_oprn_chp PF09534.10 KFO99245.1 - 0.33 10.7 2.1 0.61 9.9 2.1 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CHGN PF05679.16 KFO99246.1 - 2.2e-201 670.2 1.8 2.5e-201 670.0 1.8 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 KFO99246.1 - 9e-14 51.5 0.0 1.5e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Glyco_transf_7C PF02709.14 KFO99246.1 - 3.1e-09 36.4 0.2 7.7e-09 35.1 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KFO99246.1 - 1.5e-05 24.6 0.9 0.00049 19.6 0.2 2.4 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Galactosyl_T PF01762.21 KFO99246.1 - 0.00024 21.0 0.1 0.0049 16.7 0.1 2.9 2 1 0 2 2 2 1 Galactosyltransferase Glyco_transf_21 PF13506.6 KFO99246.1 - 0.02 14.4 0.0 0.23 10.9 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KFO99246.1 - 0.16 11.7 0.0 14 5.4 0.0 2.9 3 0 0 3 3 3 0 Glycosyl transferase family 2 Pkinase PF00069.25 KFO99247.1 - 7.8e-39 133.6 0.0 3.2e-38 131.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO99247.1 - 1.8e-36 125.8 0.0 3e-36 125.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 KFO99247.1 - 4.6e-26 90.4 20.9 1.7e-06 27.7 1.8 6.3 6 0 0 6 6 6 5 Leucine rich repeat COR PF16095.5 KFO99247.1 - 6.4e-25 88.1 0.1 1.4e-24 87.0 0.1 1.5 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain LRR_4 PF12799.7 KFO99247.1 - 9.3e-23 79.9 28.1 1.1e-05 25.7 1.1 8.2 6 2 2 8 8 8 7 Leucine Rich repeats (2 copies) Roc PF08477.13 KFO99247.1 - 1.4e-22 80.1 0.1 7.8e-22 77.8 0.0 2.4 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase Ank_2 PF12796.7 KFO99247.1 - 5e-13 49.4 0.4 2.1e-05 25.0 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFO99247.1 - 9.2e-07 29.3 0.2 0.0069 16.9 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFO99247.1 - 1.4e-06 28.2 0.8 0.34 11.6 0.0 5.1 4 0 0 4 4 4 1 Ankyrin repeat Ras PF00071.22 KFO99247.1 - 4.6e-06 26.3 0.0 8.9e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KFO99247.1 - 1.6e-05 24.4 0.0 3.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family LRR_1 PF00560.33 KFO99247.1 - 7.6e-05 22.7 19.4 12 6.9 0.0 10.0 9 0 0 9 9 9 0 Leucine Rich Repeat Ank_5 PF13857.6 KFO99247.1 - 0.00037 20.7 2.9 2.6 8.5 0.0 4.5 2 2 2 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 KFO99247.1 - 0.00077 19.8 0.8 2 9.0 0.1 3.9 3 1 0 3 3 3 1 Ankyrin repeat MMR_HSR1 PF01926.23 KFO99247.1 - 0.024 14.7 0.0 0.06 13.4 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase malic PF00390.19 KFO99247.1 - 0.024 14.4 0.3 2 8.1 0.0 2.3 2 0 0 2 2 2 0 Malic enzyme, N-terminal domain TniB PF05621.11 KFO99247.1 - 0.053 12.9 0.2 0.14 11.6 0.1 1.7 2 0 0 2 2 2 0 Bacterial TniB protein Aldedh PF00171.22 KFO99248.1 - 2e-184 613.4 0.0 2.3e-184 613.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KFO99248.1 - 0.0071 15.8 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Ank_2 PF12796.7 KFO99249.1 - 1.5e-32 112.0 0.0 8.5e-14 51.9 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFO99249.1 - 5.3e-31 106.6 7.2 1.6e-10 41.3 0.0 6.0 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 KFO99249.1 - 3.9e-29 99.8 0.7 5.8e-05 23.4 0.0 6.8 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 KFO99249.1 - 1.9e-26 91.8 2.6 5.8e-06 26.5 0.1 4.8 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFO99249.1 - 9.2e-24 80.9 2.4 4.7e-05 23.5 0.0 7.4 7 1 0 7 7 7 5 Ankyrin repeat SOCS_box PF07525.16 KFO99249.1 - 2.4e-08 34.2 4.2 3.1e-08 33.8 1.9 2.4 2 0 0 2 2 2 1 SOCS box LINES_N PF14694.6 KFO99250.1 - 1.8e-134 448.7 2.9 3.1e-134 447.9 2.9 1.4 1 0 0 1 1 1 1 Lines N-terminus LINES_C PF14695.6 KFO99250.1 - 3e-18 65.0 1.0 9e-18 63.4 1.0 1.9 1 0 0 1 1 1 1 Lines C-terminus ADAM_spacer1 PF05986.14 KFO99251.1 - 3.5e-28 97.9 0.0 6.1e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 ADAM_CR_2 PF17771.1 KFO99251.1 - 1e-22 80.4 12.1 9.3e-21 74.1 6.6 6.8 5 2 1 6 6 5 2 ADAM cysteine-rich domain Reprolysin PF01421.19 KFO99251.1 - 2.2e-20 73.4 0.8 9.1e-16 58.4 0.2 2.7 2 0 0 2 2 2 2 Reprolysin (M12B) family zinc metalloprotease TSP_1 PF00090.19 KFO99251.1 - 1.1e-16 60.8 77.1 1.5e-10 41.1 10.3 7.2 6 1 0 6 6 5 3 Thrombospondin type 1 domain Reprolysin_5 PF13688.6 KFO99251.1 - 6.6e-13 49.3 0.9 3e-12 47.1 0.9 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFO99251.1 - 2.7e-10 40.8 0.0 5.8e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFO99251.1 - 6.2e-07 29.5 1.1 3e-06 27.3 1.2 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFO99251.1 - 2e-05 24.3 1.1 7.7e-05 22.4 0.1 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like PLAC PF08686.11 KFO99251.1 - 0.0026 18.5 9.4 0.0026 18.5 9.4 3.1 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain Peptidase_M10 PF00413.24 KFO99251.1 - 0.0051 16.7 0.0 0.0081 16.0 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.9 KFO99251.1 - 0.14 11.1 0.2 0.28 10.1 0.2 1.4 1 0 0 1 1 1 0 Peptidase M66 SRF-TF PF00319.18 KFO99252.1 - 5.6e-24 83.4 0.4 9.5e-24 82.6 0.4 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C PF12347.8 KFO99252.1 - 3.5e-07 30.1 0.0 3.5e-07 30.1 0.0 3.0 4 0 0 4 4 4 1 Holliday junction regulator protein family C-terminal repeat GHD PF17834.1 KFO99252.1 - 0.13 12.3 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 Beta-sandwich domain in beta galactosidase LRR_8 PF13855.6 KFO99253.1 - 1.2e-26 92.3 34.3 1.5e-11 43.8 1.7 4.6 1 1 3 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 KFO99253.1 - 1.7e-16 60.0 19.5 1.2e-06 28.7 0.5 5.8 2 1 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFO99253.1 - 0.00014 21.9 15.6 23 6.1 0.0 8.1 8 1 0 8 8 8 2 Leucine Rich Repeat LRR_9 PF14580.6 KFO99253.1 - 0.00015 21.3 8.1 0.0016 17.9 1.0 2.9 2 1 0 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 KFO99253.1 - 0.11 12.6 11.4 24 5.3 0.1 6.3 6 0 0 6 6 6 0 Leucine Rich repeat Filament PF00038.21 KFO99254.1 - 5.4e-25 88.6 33.3 5.4e-25 88.6 33.3 3.1 2 1 0 2 2 2 1 Intermediate filament protein Pkinase_Tyr PF07714.17 KFO99255.1 - 3.3e-95 318.3 0.0 4.7e-95 317.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO99255.1 - 2.4e-40 138.6 0.0 3.9e-40 137.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.20 KFO99255.1 - 9.1e-33 113.2 33.6 9.1e-33 113.2 33.6 2.1 2 0 0 2 2 2 1 Furin-like cysteine rich region Recep_L_domain PF01030.24 KFO99255.1 - 5.8e-30 103.7 0.7 1.1e-29 102.8 0.7 1.5 1 0 0 1 1 1 1 Receptor L domain fn3 PF00041.21 KFO99255.1 - 2.6e-19 69.4 6.9 2.3e-06 27.9 0.1 4.7 4 1 0 4 4 4 4 Fibronectin type III domain Kinase-like PF14531.6 KFO99255.1 - 0.00077 18.9 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Insulin_TMD PF17870.1 KFO99255.1 - 0.076 13.1 0.3 0.18 11.9 0.3 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Peptidase_C15 PF01470.17 KFO99256.1 - 3.7e-18 66.4 0.0 4.7e-18 66.1 0.0 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase PgaPase_1 PF06162.12 KFO99256.1 - 3.9e-05 23.5 0.0 5.3e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Putative pyroglutamyl peptidase PgaPase_1 Acetyltransf_13 PF13880.6 KFO99257.1 - 0.022 14.7 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_7 PF13508.7 KFO99257.1 - 0.022 15.2 0.0 0.057 13.9 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFO99257.1 - 0.074 13.3 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-SCNM1 PF15803.5 KFO99257.1 - 0.11 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of sodium channel modifier 1 Acetyltransf_10 PF13673.7 KFO99257.1 - 0.17 11.8 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glutaredoxin PF00462.24 KFO99258.1 - 3.9e-39 132.7 0.1 5.2e-17 61.8 0.0 3.7 4 0 0 4 4 4 2 Glutaredoxin Thioredoxin PF00085.20 KFO99258.1 - 1.3e-17 63.7 0.1 4.4e-17 62.0 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 KFO99258.1 - 7.3e-07 29.6 0.1 9.6e-06 26.0 0.0 2.8 3 1 0 3 3 3 1 Thioredoxin-like domain SH3BGR PF04908.15 KFO99258.1 - 3.8e-05 23.8 0.0 0.095 12.9 0.0 2.6 2 0 0 2 2 2 2 SH3-binding, glutamic acid-rich protein DIM1 PF02966.16 KFO99258.1 - 0.00012 21.9 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.6 KFO99258.1 - 0.0017 18.7 0.1 0.22 11.9 0.0 3.1 2 1 1 3 3 3 2 Thioredoxin-like Phosducin PF02114.16 KFO99258.1 - 0.0055 15.7 0.0 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Phosducin OST3_OST6 PF04756.13 KFO99258.1 - 0.011 15.1 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family TraF PF13728.6 KFO99258.1 - 0.019 14.8 0.2 0.089 12.6 0.1 2.0 3 0 0 3 3 3 0 F plasmid transfer operon protein RdRP PF05183.12 KFO99258.1 - 0.026 13.2 0.0 4.3 5.8 0.0 2.1 1 1 0 2 2 2 0 RNA dependent RNA polymerase HyaE PF07449.11 KFO99258.1 - 0.045 13.7 0.0 0.97 9.4 0.0 2.8 4 1 0 4 4 4 0 Hydrogenase-1 expression protein HyaE TrbC_Ftype PF09673.10 KFO99258.1 - 0.16 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein COE1_DBD PF16422.5 KFO99259.1 - 2.5e-141 468.9 2.9 3.4e-141 468.5 2.9 1.2 1 0 0 1 1 1 1 Transcription factor COE1 DNA-binding domain COE1_HLH PF16423.5 KFO99259.1 - 1.2e-35 121.0 3.0 5.2e-29 99.7 0.4 2.4 2 0 0 2 2 2 2 Transcription factor COE1 helix-loop-helix domain TIG PF01833.24 KFO99259.1 - 1e-12 47.9 0.1 1e-12 47.9 0.1 2.0 2 0 0 2 2 2 1 IPT/TIG domain DNA_binding_1 PF01035.20 KFO99260.1 - 1.2e-26 92.6 0.0 1.6e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N PF02870.15 KFO99260.1 - 3.3e-08 34.2 0.0 5.3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain LMBR1 PF04791.16 KFO99263.1 - 8.6 5.1 6.5 11 4.8 6.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein KI67R PF08065.12 KFO99264.1 - 6.9 7.3 19.9 1.9 9.1 0.1 4.0 1 1 4 5 5 5 0 KI67R (NUC007) repeat KI67R PF08065.12 KFO99265.1 - 8.6e-24 84.2 13.5 5.3e-09 36.6 0.8 2.4 1 1 2 3 3 3 3 KI67R (NUC007) repeat Plasmid_RAQPRD PF09686.10 KFO99265.1 - 0.037 14.2 0.5 1.1 9.5 0.0 2.7 1 1 1 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Sybindin PF04099.12 KFO99265.1 - 0.079 12.9 0.0 0.6 10.0 0.0 1.9 1 1 1 2 2 2 0 Sybindin-like family HTH_49 PF18010.1 KFO99265.1 - 0.084 12.7 0.0 47 4.0 0.0 3.7 4 0 0 4 4 4 0 Cry35Ab1 HTH C-terminal domain BaffR-Tall_bind PF09256.10 KFO99265.1 - 9.2 6.1 14.6 95 2.9 0.2 4.9 5 0 0 5 5 5 0 BAFF-R, TALL-1 binding Herpes_US9 PF06072.11 KFO99266.1 - 0.0045 16.8 0.9 0.79 9.7 0.1 2.2 2 0 0 2 2 2 2 Alphaherpesvirus tegument protein US9 TGF_beta_GS PF08515.12 KFO99266.1 - 0.011 15.2 5.6 14 5.3 0.1 3.8 4 0 0 4 4 4 0 Transforming growth factor beta type I GS-motif Chromadorea_ALT PF05535.12 KFO99266.1 - 0.031 14.4 2.0 7.5 6.8 0.2 3.4 1 1 3 4 4 4 0 Chromadorea ALT protein Nucleoporin_FG2 PF15967.5 KFO99266.1 - 0.048 12.2 0.5 0.06 11.9 0.5 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region APC1_C PF18122.1 KFO99266.1 - 0.071 13.1 0.2 17 5.3 0.0 2.8 1 1 2 3 3 3 0 Anaphase-promoting complex sub unit 1 C-terminal domain DAN PF03045.15 KFO99266.1 - 0.082 12.9 3.1 6.3 6.9 1.1 2.3 1 1 1 2 2 2 0 DAN domain PP1_bind PF15276.6 KFO99268.1 - 1.3e-22 79.8 0.5 2e-22 79.2 0.5 1.3 1 0 0 1 1 1 1 Protein phosphatase 1 binding FHA PF00498.26 KFO99269.1 - 2.9e-14 53.2 0.0 4.1e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFO99269.1 - 3.6e-10 40.0 0.0 4.5e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 KFO99269.1 - 0.00082 19.6 0.0 0.00098 19.3 0.0 1.2 1 0 0 1 1 1 1 FHA domain DUF2207 PF09972.9 KFO99270.1 - 0.031 13.1 0.7 0.12 11.1 0.7 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) CrgA PF06781.12 KFO99270.1 - 0.15 12.1 0.4 3.6 7.7 0.0 2.5 2 0 0 2 2 2 0 Cell division protein CrgA DUF3169 PF11368.8 KFO99270.1 - 0.3 10.6 6.7 0.038 13.5 1.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3169) Baculo_11_kDa PF06143.11 KFO99270.1 - 4.1 7.0 5.7 9.4 5.9 0.1 3.4 4 0 0 4 4 4 0 Baculovirus 11 kDa family YoqO PF14037.6 KFO99270.1 - 7.1 7.2 8.6 3.8 8.1 0.2 3.1 3 1 0 3 3 3 0 YoqO-like protein Forkhead PF00250.18 KFO99271.1 - 3.7e-39 132.9 0.0 4.3e-39 132.7 0.0 1.0 1 0 0 1 1 1 1 Forkhead domain FAM196 PF15265.6 KFO99273.1 - 2.9e-175 584.5 16.8 2.3e-101 340.7 5.4 2.0 1 1 1 2 2 2 2 FAM196 family Flu_C_NS2 PF03555.14 KFO99274.1 - 0.16 12.1 0.2 0.24 11.6 0.2 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS2) DOCK-C2 PF14429.6 KFO99275.1 - 2.4e-38 131.9 0.0 3e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DOCK_N PF16172.5 KFO99275.1 - 4.5e-14 52.2 0.0 6.4e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 DOCK N-terminus Centro_C10orf90 PF17730.1 KFO99276.1 - 7.6e-197 655.2 9.6 7.6e-197 655.2 9.6 1.5 2 0 0 2 2 2 1 Centrosomal C10orf90 ALMS_motif PF15309.6 KFO99276.1 - 9.3e-48 162.2 15.7 2.3e-47 160.9 15.7 1.7 1 0 0 1 1 1 1 ALMS motif Trimer_CC PF08954.11 KFO99276.1 - 0.078 12.5 3.3 0.27 10.8 3.3 1.9 1 0 0 1 1 1 0 Trimerisation motif Utp12 PF04003.12 KFO99276.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Dip2/Utp12 Family Reprolysin PF01421.19 KFO99277.1 - 1.5e-73 246.9 0.0 1.5e-73 246.9 0.0 1.7 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.12 KFO99277.1 - 1.1e-33 116.1 3.5 1.1e-33 116.1 3.5 3.5 3 1 0 3 3 3 1 ADAM cysteine-rich Pep_M12B_propep PF01562.19 KFO99277.1 - 1e-29 103.6 0.1 1.9e-29 102.7 0.1 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_5 PF13688.6 KFO99277.1 - 1.2e-20 74.5 0.0 2.4e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Disintegrin PF00200.23 KFO99277.1 - 9.8e-19 67.9 24.6 9.8e-19 67.9 24.6 4.1 3 1 1 4 4 4 1 Disintegrin Reprolysin_3 PF13582.6 KFO99277.1 - 1.4e-14 54.6 0.0 2.7e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFO99277.1 - 3.9e-14 52.8 0.0 6.1e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFO99277.1 - 2.3e-13 50.5 0.0 4.2e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 KFO99277.1 - 0.061 12.3 0.2 0.11 11.4 0.2 1.3 1 0 0 1 1 1 0 Peptidase M66 Zincin_1 PF06262.11 KFO99277.1 - 0.1 12.7 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Zincin-like metallopeptidase HA2 PF04408.23 KFO99278.1 - 9.6e-20 70.9 0.2 3.4e-19 69.1 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFO99278.1 - 1.6e-13 50.8 0.1 6.9e-13 48.8 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DUF4821 PF16092.5 KFO99278.1 - 0.32 10.6 2.0 4.8 6.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4821) BCIP PF13862.6 KFO99279.1 - 8.3e-57 192.3 3.5 1e-56 192.0 3.5 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein DPRP PF04244.13 KFO99279.1 - 0.026 14.4 0.1 0.13 12.1 0.1 2.0 1 1 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein PSCyt3 PF07627.11 KFO99279.1 - 0.18 12.1 0.7 0.39 11.0 0.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1588) HEM4 PF02602.15 KFO99280.1 - 4.3e-47 160.4 0.0 4.8e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Cas_Csd1 PF09709.10 KFO99280.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csd1) 2-Hacid_dh_C PF02826.19 KFO99281.1 - 2.4e-55 186.6 0.0 4.1e-55 185.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFO99281.1 - 1.9e-29 102.0 0.1 2.3e-29 101.7 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFO99281.1 - 0.042 14.0 0.0 0.092 12.9 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AnkUBD PF18418.1 KFO99282.1 - 1.4e-50 169.3 0.1 3.2e-50 168.2 0.1 1.6 1 0 0 1 1 1 1 Ankyrin ubiquitin-binding domain OTU PF02338.19 KFO99282.1 - 7.1e-39 133.2 0.0 2.4e-38 131.5 0.0 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease zf-RanBP PF00641.18 KFO99282.1 - 1e-08 34.3 37.7 7.4e-06 25.2 6.2 4.0 4 0 0 4 4 4 3 Zn-finger in Ran binding protein and others DZR PF12773.7 KFO99282.1 - 0.22 11.6 17.3 0.69 10.0 7.1 3.1 3 1 0 3 3 3 0 Double zinc ribbon Methyltransf_31 PF13847.6 KFO99283.1 - 7.9e-21 74.4 0.0 1.1e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFO99283.1 - 3.8e-11 43.5 0.0 6.6e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFO99283.1 - 7.5e-09 36.2 0.0 1.2e-08 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFO99283.1 - 1e-08 35.7 0.0 1.7e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFO99283.1 - 1.4e-08 34.7 0.0 3.1e-08 33.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFO99283.1 - 5.6e-05 22.7 0.0 7.3e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KFO99283.1 - 0.00011 21.7 0.0 0.00016 21.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 KFO99283.1 - 0.0029 17.0 0.0 0.0044 16.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.20 KFO99283.1 - 0.01 15.1 0.0 0.017 14.4 0.0 1.3 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 KFO99283.1 - 0.016 14.7 0.0 0.024 14.1 0.0 1.4 1 1 0 1 1 1 0 Putative methyltransferase AdoMet_MTase PF07757.13 KFO99283.1 - 0.026 14.8 0.0 0.043 14.2 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_24 PF13578.6 KFO99283.1 - 0.088 13.8 0.0 0.12 13.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 KFO99283.1 - 0.088 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 KFO99283.1 - 0.09 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KFO99283.1 - 0.09 12.5 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FAM53 PF15242.6 KFO99284.1 - 2.1e-90 303.7 19.0 5e-90 302.4 19.0 1.6 1 1 0 1 1 1 1 Family of FAM53 Hydrolase_like PF13242.6 KFO99285.1 - 1.4e-20 73.1 0.0 3.3e-20 71.9 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KFO99285.1 - 8.7e-16 57.9 0.0 1.6e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFO99285.1 - 1.2e-10 41.8 0.0 2e-07 31.2 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFO99285.1 - 6.2e-08 33.2 0.2 4.2e-06 27.2 0.2 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Aminotran_3 PF00202.21 KFO99286.1 - 2.6e-122 408.4 0.0 3.2e-122 408.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KFO99286.1 - 0.0092 15.2 0.0 0.041 13.0 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II Sulfotransfer_1 PF00685.27 KFO99287.1 - 2.6e-15 56.6 0.0 3.6e-12 46.3 0.0 2.2 2 0 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFO99287.1 - 1.1e-11 45.6 0.0 5.5e-11 43.3 0.0 2.1 1 1 0 1 1 1 1 Sulfotransferase family PVL_ORF50 PF07768.11 KFO99287.1 - 0.0011 19.2 0.1 0.0025 18.1 0.1 1.5 1 0 0 1 1 1 1 PVL ORF-50-like family Sulfotransfer_2 PF03567.14 KFO99287.1 - 0.025 14.5 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase family Sulfotransfer_4 PF17784.1 KFO99287.1 - 0.26 11.1 0.9 1 9.1 0.9 2.0 1 1 0 1 1 1 0 Sulfotransferase domain Peptidase_M14 PF00246.24 KFO99288.1 - 2.4e-74 250.8 0.0 3.6e-74 250.2 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase F5_F8_type_C PF00754.25 KFO99288.1 - 6.8e-28 97.3 0.1 1.7e-27 96.0 0.1 1.8 1 0 0 1 1 1 1 F5/8 type C domain CarboxypepD_reg PF13620.6 KFO99288.1 - 1.6e-12 47.5 0.0 3.7e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KFO99288.1 - 2.7e-05 24.1 0.0 5.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 CarboxypepD_reg-like domain PEGA PF08308.11 KFO99288.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 PEGA domain 7tm_1 PF00001.21 KFO99289.1 - 1.4e-33 116.3 12.2 1.9e-33 115.9 12.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFO99289.1 - 1.9e-08 34.3 15.9 4e-08 33.2 15.9 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Git3 PF11710.8 KFO99289.1 - 1.5e-05 24.9 9.9 2.2e-05 24.3 9.6 1.4 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srsx PF10320.9 KFO99289.1 - 2.5e-05 23.8 11.9 6.1e-05 22.5 11.9 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srbc PF10316.9 KFO99289.1 - 0.00023 20.7 7.3 0.00023 20.7 7.3 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc TssO PF17561.2 KFO99289.1 - 0.54 10.4 7.1 4.1 7.5 0.5 2.5 2 0 0 2 2 2 0 Type VI secretion system, TssO WD40 PF00400.32 KFO99290.1 - 1.5e-22 79.5 2.8 2.4e-05 25.0 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO99290.1 - 7.9e-07 29.3 0.0 1.2 9.5 0.0 4.3 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFO99290.1 - 0.14 11.1 0.0 0.77 8.6 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Homeodomain PF00046.29 KFO99291.1 - 8.5e-20 70.4 1.5 1.4e-19 69.7 1.5 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO99291.1 - 0.017 15.0 0.2 0.034 14.0 0.1 1.6 2 0 0 2 2 2 0 Homeobox KN domain CT_C_D PF02682.16 KFO99291.1 - 0.033 13.9 0.0 0.035 13.8 0.0 1.1 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D zf-H2C2_2 PF13465.6 KFO99292.1 - 1.5e-12 47.3 45.0 3e-07 30.5 4.0 6.3 6 0 0 6 6 6 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFO99292.1 - 2.1e-11 43.3 31.9 2.2e-05 24.1 0.1 4.6 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFO99292.1 - 7.9e-07 29.2 49.3 0.067 13.7 7.9 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO99292.1 - 0.0025 18.5 44.6 0.75 10.8 6.7 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFO99292.1 - 2.7 8.4 0.0 2.7 8.4 0.0 4.9 2 2 3 5 5 5 0 C2H2 type zinc-finger (2 copies) KTI12 PF08433.10 KFO99293.1 - 1e-13 51.4 2.6 1e-13 51.4 2.6 1.8 1 1 1 2 2 2 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KFO99293.1 - 0.0015 18.7 0.0 0.0052 17.0 0.0 1.8 2 1 0 2 2 2 1 AAA domain Selenoprotein_S PF06936.11 KFO99293.1 - 0.027 14.3 2.1 0.038 13.8 2.1 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF4259 PF14078.6 KFO99293.1 - 0.12 13.1 2.7 0.8 10.4 2.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4259) DUF4506 PF14958.6 KFO99294.1 - 1.2e-43 148.1 0.1 2.1e-43 147.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4506) RVT_1 PF00078.27 KFO99295.1 - 0.071 12.6 0.0 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Death PF00531.22 KFO99296.1 - 1.2e-05 25.3 1.4 2.5e-05 24.3 1.4 1.6 1 0 0 1 1 1 1 Death domain ZU5 PF00791.20 KFO99296.1 - 0.087 13.2 0.1 1.5 9.3 0.0 2.4 2 0 0 2 2 2 0 ZU5 domain NACHT PF05729.12 KFO99297.1 - 2.4e-05 24.3 0.1 0.0002 21.3 0.1 2.3 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KFO99297.1 - 2.8e-05 24.4 0.0 0.00012 22.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain ANAPC4_WD40 PF12894.7 KFO99297.1 - 2.9e-05 24.3 3.5 21 5.5 0.1 6.5 4 2 2 6 6 6 0 Anaphase-promoting complex subunit 4 WD40 domain AAA_16 PF13191.6 KFO99297.1 - 0.00029 21.3 0.0 0.00082 19.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 KFO99297.1 - 0.0013 19.0 0.0 0.0033 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFO99297.1 - 0.0035 17.8 0.0 0.014 15.8 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PQQ_2 PF13360.6 KFO99297.1 - 0.053 13.1 0.0 1.5 8.3 0.0 2.8 2 1 0 2 2 2 0 PQQ-like domain WD40 PF00400.32 KFO99297.1 - 0.076 13.9 0.9 11 7.0 0.2 5.1 5 0 0 5 5 5 0 WD domain, G-beta repeat STN1_2 PF09170.10 KFO99297.1 - 0.083 13.1 0.1 0.34 11.1 0.1 2.0 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 DUF4699 PF15770.5 KFO99298.1 - 2.2e-95 320.0 17.7 2.4e-95 319.9 17.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4699) Trypan_glycop_C PF10659.9 KFO99298.1 - 1.1 9.6 9.8 5 7.6 4.8 2.7 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain RELT PF12606.8 KFO99299.1 - 5.9e-26 89.2 0.9 9.5e-26 88.5 0.9 1.3 1 0 0 1 1 1 1 Tumour necrosis factor receptor superfamily member 19 PHC2_SAM_assoc PF16616.5 KFO99299.1 - 0.86 10.4 6.6 6.7 7.5 0.4 2.4 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 PGM_PMM_I PF02878.16 KFO99300.1 - 1.7e-36 125.0 0.0 3.2e-36 124.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KFO99300.1 - 3.9e-24 85.2 0.0 1.3e-23 83.6 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KFO99300.1 - 2.1e-12 47.3 0.2 9.6e-12 45.1 0.0 2.3 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 KFO99300.1 - 8.7e-06 25.8 0.0 2.6e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RabGAP-TBC PF00566.18 KFO99301.1 - 8.5e-53 179.2 0.7 8.5e-53 179.2 0.7 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF3350 PF11830.8 KFO99301.1 - 2.4e-22 79.0 1.9 2.4e-22 79.0 1.9 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3350) PID PF00640.23 KFO99301.1 - 2.9e-13 50.1 4.2 7e-09 35.9 0.3 3.3 3 0 0 3 3 3 2 Phosphotyrosine interaction domain (PTB/PID) zf-C2H2 PF00096.26 KFO99302.1 - 2.4e-16 59.2 22.9 2e-06 27.9 2.7 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO99302.1 - 9.8e-13 47.9 8.7 3.1e-09 36.8 1.0 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFO99302.1 - 1.5e-08 34.8 20.1 0.0022 18.7 1.8 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFO99302.1 - 0.041 14.3 2.7 7.5 7.1 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFO99302.1 - 0.12 12.7 3.7 8.3 6.8 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFO99302.1 - 0.12 12.4 9.4 0.38 10.8 0.6 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KFO99302.1 - 0.65 10.1 4.3 3.7 7.7 2.9 2.1 1 1 2 3 3 3 0 Aberrant zinc-finger FOXP-CC PF16159.5 KFO99302.1 - 1.1 9.9 8.0 4.6 7.9 0.7 3.2 2 1 1 3 3 3 0 FOXP coiled-coil domain TIR PF01582.20 KFO99303.1 - 4.5e-25 88.5 0.1 8.1e-25 87.6 0.1 1.4 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.6 KFO99303.1 - 5.6e-16 58.0 14.7 3.3e-08 33.2 0.3 4.8 3 1 2 5 5 5 4 Leucine rich repeat TIR_2 PF13676.6 KFO99303.1 - 1.6e-15 57.7 0.0 6e-15 55.9 0.0 2.0 2 0 0 2 2 2 1 TIR domain LRR_4 PF12799.7 KFO99303.1 - 4.8e-13 49.1 19.1 1.4e-05 25.4 0.3 5.6 2 2 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFO99303.1 - 9.8e-10 37.7 14.0 0.055 13.5 0.3 6.5 7 0 0 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.33 KFO99303.1 - 0.00057 20.1 12.8 3.6 8.5 0.2 6.4 5 2 0 5 5 5 2 Leucine Rich Repeat LRR_9 PF14580.6 KFO99303.1 - 0.21 11.1 1.4 5.5 6.4 0.0 2.7 3 0 0 3 3 3 0 Leucine-rich repeat Pentapeptide_4 PF13599.6 KFO99303.1 - 0.31 11.2 2.4 9.4 6.5 1.3 2.8 2 1 0 2 2 2 0 Pentapeptide repeats (9 copies) TIR PF01582.20 KFO99305.1 - 1e-24 87.3 0.0 1.7e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.6 KFO99305.1 - 5e-16 58.2 15.0 1.2e-07 31.4 0.4 4.9 4 1 2 6 6 6 4 Leucine rich repeat TIR_2 PF13676.6 KFO99305.1 - 3.7e-15 56.6 0.0 9.5e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 KFO99305.1 - 3e-12 46.5 27.4 4.8e-05 23.6 0.4 6.8 3 3 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFO99305.1 - 4.8e-09 35.6 11.4 0.076 13.1 0.3 7.0 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 KFO99305.1 - 3.6e-05 23.7 9.7 3.9 8.4 0.1 6.7 5 1 0 5 5 5 2 Leucine Rich Repeat LRRCT PF01463.24 KFO99305.1 - 5.5e-05 23.4 0.0 0.00029 21.1 0.0 2.4 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain Pentapeptide_4 PF13599.6 KFO99305.1 - 0.02 15.1 2.0 15 5.8 0.2 3.8 2 1 1 3 3 3 0 Pentapeptide repeats (9 copies) LRR_9 PF14580.6 KFO99305.1 - 0.05 13.1 0.3 11 5.5 0.0 2.5 2 0 0 2 2 2 0 Leucine-rich repeat TMEM156 PF15106.6 KFO99307.1 - 5.2e-83 277.9 16.5 5.9e-83 277.7 16.5 1.0 1 0 0 1 1 1 1 TMEM156 protein family RE_BsaWI PF18643.1 KFO99307.1 - 0.08 12.9 0.4 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 BsaWI restriction endonuclease type 2 WD40_3 PF15911.5 KFO99308.1 - 1.3e-28 98.7 2.1 1.1e-27 95.7 0.1 3.3 4 0 0 4 4 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO99308.1 - 2.7e-12 46.8 3.4 0.00019 21.7 0.3 5.3 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 KFO99308.1 - 1.2e-10 41.5 3.3 0.00019 21.3 0.2 5.2 4 1 1 5 5 5 2 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 KFO99308.1 - 4.9e-08 32.5 7.1 0.011 14.8 0.4 4.1 4 0 0 4 4 4 3 Coatomer WD associated region IKI3 PF04762.12 KFO99308.1 - 0.00014 20.0 2.8 0.068 11.2 0.1 3.0 1 1 0 2 2 2 2 IKI3 family TPR_14 PF13428.6 KFO99308.1 - 0.0011 19.6 4.6 6.4 7.9 0.0 7.1 8 0 0 8 8 7 1 Tetratricopeptide repeat eIF2A PF08662.11 KFO99308.1 - 0.0057 16.6 0.3 0.056 13.3 0.2 2.6 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A TPR_19 PF14559.6 KFO99308.1 - 0.0092 16.5 5.2 6.4 7.4 0.1 5.1 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFO99308.1 - 0.013 15.6 14.2 13 6.2 0.3 7.1 7 1 0 7 7 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO99308.1 - 0.023 14.9 5.2 6.6 7.0 0.5 4.9 3 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 SdiA-regulated PF06977.11 KFO99308.1 - 0.032 13.5 0.0 11 5.2 0.0 3.1 3 0 0 3 3 3 0 SdiA-regulated WD40 PF00400.32 KFO99308.1 - 0.039 14.8 8.4 13 6.8 0.0 6.3 5 1 1 6 6 6 0 WD domain, G-beta repeat Mcl1_mid PF12341.8 KFO99308.1 - 0.09 12.1 0.0 0.78 9.0 0.0 2.2 1 1 1 2 2 2 0 Minichromosome loss protein, Mcl1, middle region TPR_8 PF13181.6 KFO99308.1 - 0.18 12.1 12.0 2.1 8.8 0.2 6.7 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFO99308.1 - 0.53 10.4 8.4 41 4.5 0.1 5.7 6 1 0 6 6 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFO99308.1 - 0.68 10.3 6.8 50 4.3 0.0 5.4 5 1 0 6 6 6 0 Tetratricopeptide repeat SNAP PF14938.6 KFO99308.1 - 0.83 9.0 8.8 0.21 11.0 2.0 3.0 2 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP zf-ribbon_3 PF13248.6 KFO99308.1 - 1.1 8.8 14.4 0.44 10.0 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 KFO99308.1 - 1.5 8.9 14.4 1 9.5 10.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 KFO99308.1 - 9.8 6.3 10.9 9.4 6.3 0.8 2.7 1 1 1 2 2 2 0 zinc-ribbons RFC1 PF08519.12 KFO99309.1 - 7.7e-60 201.6 0.0 1.6e-59 200.5 0.0 1.6 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KFO99309.1 - 3.8e-17 62.4 0.0 1.2e-16 60.8 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KFO99309.1 - 2.7e-15 57.0 0.0 6.2e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PTCB-BRCT PF12738.7 KFO99309.1 - 8.6e-07 28.8 0.1 2.5e-06 27.3 0.1 1.9 1 0 0 1 1 1 1 twin BRCT domain Rad17 PF03215.15 KFO99309.1 - 9.2e-05 22.4 0.3 0.0016 18.4 0.1 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 KFO99309.1 - 0.00026 21.0 0.1 0.0012 18.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFO99309.1 - 0.00048 20.1 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KFO99309.1 - 0.00065 20.1 0.0 0.0033 17.8 0.0 2.3 1 1 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 KFO99309.1 - 0.00074 19.9 0.0 0.0026 18.1 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFO99309.1 - 0.00087 19.6 0.8 0.0039 17.5 0.0 2.5 3 0 0 3 3 1 1 AAA domain AAA_7 PF12775.7 KFO99309.1 - 0.0012 18.3 0.0 0.0025 17.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 KFO99309.1 - 0.0013 18.9 0.0 0.0034 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KFO99309.1 - 0.0015 18.3 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KFO99309.1 - 0.0032 18.0 0.1 0.012 16.2 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFO99309.1 - 0.0061 16.3 0.0 0.025 14.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KFO99309.1 - 0.007 15.7 0.0 0.018 14.3 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin BRCT_2 PF16589.5 KFO99309.1 - 0.0098 16.3 0.0 0.033 14.6 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain AAA_17 PF13207.6 KFO99309.1 - 0.021 15.3 1.8 0.043 14.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 KFO99309.1 - 0.029 13.6 0.1 0.082 12.1 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain NTPase_1 PF03266.15 KFO99309.1 - 0.047 13.6 0.2 0.15 12.0 0.1 1.8 1 1 1 2 2 2 0 NTPase Glyco_hydro_1 PF00232.18 KFO99310.1 - 9.5e-166 551.7 16.8 1.1e-82 277.9 0.8 3.1 2 1 1 3 3 3 3 Glycosyl hydrolase family 1 Self-incomp_S1 PF05938.11 KFO99310.1 - 0.046 14.3 0.1 0.33 11.5 0.0 2.6 2 1 0 2 2 2 0 Plant self-incompatibility protein S1 Ribosomal_L6 PF00347.23 KFO99311.1 - 2.8e-34 117.6 1.6 1.6e-16 60.7 0.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 LIAS_N PF16881.5 KFO99312.1 - 6.2e-44 148.8 0.4 1.3e-43 147.8 0.4 1.6 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KFO99312.1 - 4.2e-18 66.3 0.0 6.3e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily ROS_MUCR PF05443.11 KFO99312.1 - 0.1 12.6 0.1 0.23 11.5 0.0 1.7 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein UDPG_MGDP_dh_N PF03721.14 KFO99313.1 - 4.8e-47 159.9 0.2 1.3e-46 158.6 0.1 1.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KFO99313.1 - 8.4e-37 125.8 0.0 2e-35 121.4 0.0 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 KFO99313.1 - 3.1e-22 78.6 0.0 1.3e-21 76.6 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Ldh_1_N PF00056.23 KFO99313.1 - 0.0098 16.0 0.1 6.2 6.9 0.0 3.7 2 2 2 4 4 4 1 lactate/malate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KFO99313.1 - 0.079 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF4853 PF16145.5 KFO99313.1 - 0.12 12.5 0.0 2.4 8.3 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4853) DUF2615 PF11027.8 KFO99314.1 - 1.8e-41 140.5 0.0 2.2e-41 140.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) UQ_con PF00179.26 KFO99315.1 - 2.7e-42 143.7 0.0 3.4e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 KFO99315.1 - 4.1e-11 42.5 0.0 9.3e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.6 KFO99315.1 - 3.5e-06 26.8 0.0 5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KFO99315.1 - 0.0053 17.0 0.0 0.008 16.5 0.0 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KFO99315.1 - 0.025 14.4 0.0 0.044 13.6 0.0 1.4 1 1 0 1 1 1 0 UEV domain UBA_3 PF09288.10 KFO99315.1 - 0.093 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Polysacc_lyase PF14099.6 KFO99315.1 - 0.13 12.1 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide lyase Cnd1 PF12717.7 KFO99316.1 - 0.0013 18.8 8.7 1.1 9.3 0.0 5.7 4 2 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFO99316.1 - 0.028 14.7 1.8 6.5 7.3 0.0 5.2 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.6 KFO99316.1 - 0.52 10.9 3.9 40 4.8 0.0 5.0 5 0 0 5 5 5 0 HEAT-like repeat Ras PF00071.22 KFO99317.1 - 9.9e-45 152.0 0.0 1.2e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO99317.1 - 2.3e-22 79.5 0.0 3.4e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO99317.1 - 6.3e-06 25.7 0.0 8.4e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFO99317.1 - 0.025 14.7 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 KFO99317.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 KFO99317.1 - 0.18 11.7 0.0 0.58 10.0 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase Neur_chan_LBD PF02931.23 KFO99320.1 - 4.9e-68 228.8 2.2 6.6e-68 228.4 2.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFO99320.1 - 1.1e-48 166.4 0.2 1.4e-48 166.0 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region RRM_1 PF00076.22 KFO99321.1 - 3.8e-39 132.4 0.8 1.6e-15 56.7 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFO99321.1 - 5.9e-06 26.3 0.3 0.019 15.1 0.1 3.7 3 1 0 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 KFO99321.1 - 0.00022 20.8 0.0 0.056 13.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KFO99321.1 - 0.0013 19.0 0.2 0.63 10.3 0.1 3.1 2 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter Limkain-b1 PF11608.8 KFO99321.1 - 0.024 14.7 0.1 0.85 9.7 0.0 2.9 3 0 0 3 3 3 0 Limkain b1 ERp29 PF07749.12 KFO99321.1 - 0.069 14.1 0.0 0.21 12.5 0.0 1.8 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Nup35_RRM_2 PF14605.6 KFO99321.1 - 0.069 13.2 1.0 4.4 7.4 0.0 2.7 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Methyltr_RsmB-F PF01189.17 KFO99322.1 - 6e-07 29.3 0.1 3.4e-06 26.9 0.1 2.2 2 1 0 2 2 2 1 16S rRNA methyltransferase RsmB/F E3_UbLigase_EDD PF11547.8 KFO99322.1 - 0.12 12.1 0.0 0.37 10.5 0.0 1.8 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD Peptidase_C12 PF01088.21 KFO99323.1 - 1.6e-52 178.3 0.3 1.9e-52 178.1 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 ObR_Ig PF18589.1 KFO99323.1 - 0.14 12.5 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Obesity receptor immunoglobulin like domain DUF4757 PF15949.5 KFO99324.1 - 1.8e-65 220.6 10.2 1.8e-65 220.6 10.2 3.9 3 1 0 4 4 4 1 Domain of unknown function (DUF4757) LIM PF00412.22 KFO99324.1 - 1.6e-07 31.5 0.3 4.2e-07 30.1 0.3 1.8 1 0 0 1 1 1 1 LIM domain zf-UDP PF14569.6 KFO99324.1 - 0.11 12.6 0.1 0.51 10.5 0.1 2.2 1 0 0 1 1 1 0 Zinc-binding RING-finger zinc_ribbon_6 PF14599.6 KFO99324.1 - 4.6 7.3 5.3 14 5.8 0.0 3.7 3 0 0 3 3 3 0 Zinc-ribbon SET PF00856.28 KFO99324.1 - 9 6.6 12.2 0.3 11.5 1.4 2.6 2 1 0 2 2 2 0 SET domain Homeodomain PF00046.29 KFO99325.1 - 5.9e-14 51.7 0.5 9.2e-14 51.0 0.5 1.3 1 0 0 1 1 1 1 Homeodomain Myb_DNA-bind_3 PF12776.7 KFO99325.1 - 0.026 15.5 0.0 1.5 9.9 0.0 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain UPF0121 PF03661.13 KFO99326.1 - 9.8e-94 313.3 17.9 1.1e-93 313.1 17.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Cation_efflux PF01545.21 KFO99327.1 - 7.6e-32 110.7 8.0 9.4e-32 110.4 8.0 1.1 1 0 0 1 1 1 1 Cation efflux family XPA_C PF05181.12 KFO99327.1 - 0.00013 21.9 0.0 0.0003 20.7 0.0 1.7 1 0 0 1 1 1 1 XPA protein C-terminus ZT_dimer PF16916.5 KFO99327.1 - 0.0044 17.1 1.3 0.14 12.3 0.2 3.0 2 1 1 3 3 3 1 Dimerisation domain of Zinc Transporter IF3_C PF00707.22 KFO99327.1 - 0.02 14.8 1.3 1.6 8.8 0.2 2.6 2 0 0 2 2 2 0 Translation initiation factor IF-3, C-terminal domain Ion_trans_N PF08412.10 KFO99327.1 - 0.031 13.9 0.0 0.081 12.5 0.0 1.6 1 0 0 1 1 1 0 Ion transport protein N-terminal Deltameth_res PF16020.5 KFO99327.1 - 0.11 12.4 0.4 0.43 10.5 0.0 2.2 2 0 0 2 2 2 0 Deltamethrin resistance BEN PF10523.9 KFO99328.1 - 2.1e-13 50.3 0.0 4.5e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 BEN domain bZIP_1 PF00170.21 KFO99328.1 - 0.0048 17.0 0.2 0.013 15.5 0.2 1.8 1 0 0 1 1 1 1 bZIP transcription factor Uds1 PF15456.6 KFO99328.1 - 0.014 15.5 0.1 0.029 14.6 0.1 1.5 1 0 0 1 1 1 0 Up-regulated During Septation Cep57_CLD_2 PF14197.6 KFO99328.1 - 0.019 15.1 0.5 0.16 12.1 0.2 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Shugoshin_N PF07558.11 KFO99328.1 - 0.027 14.4 1.6 0.027 14.4 1.6 1.9 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region bZIP_2 PF07716.15 KFO99328.1 - 0.043 13.9 3.9 0.097 12.8 3.9 1.5 1 0 0 1 1 1 0 Basic region leucine zipper NYD-SP28_assoc PF14775.6 KFO99328.1 - 0.043 13.9 1.9 0.12 12.5 1.9 1.8 1 0 0 1 1 1 0 Sperm tail C-terminal domain Herpes_BLRF2 PF05812.12 KFO99328.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Shisa PF13908.6 KFO99329.1 - 8.7e-22 78.3 0.8 9.9e-22 78.1 0.8 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator PhoLip_ATPase_C PF16212.5 KFO99330.1 - 2.7e-86 289.4 20.3 2.7e-86 289.4 20.3 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFO99330.1 - 2.4e-19 68.8 4.2 7.7e-19 67.2 4.2 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFO99330.1 - 9.3e-13 48.9 0.1 0.00012 22.4 0.0 3.5 4 0 0 4 4 4 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFO99330.1 - 8.2e-11 41.8 1.6 1e-10 41.4 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KFO99330.1 - 3.3e-10 39.9 0.0 3.6e-09 36.6 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFO99330.1 - 0.0002 21.2 0.3 0.012 15.3 0.1 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Fzo_mitofusin PF04799.13 KFO99330.1 - 0.049 13.2 0.3 0.13 11.8 0.3 1.6 1 0 0 1 1 1 0 fzo-like conserved region Glutaredoxin PF00462.24 KFO99331.1 - 6.5e-10 39.1 0.1 1.1e-08 35.1 0.2 2.4 2 0 0 2 2 2 1 Glutaredoxin SH3BGR PF04908.15 KFO99331.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein DnaJ_CXXCXGXG PF00684.19 KFO99331.1 - 1.3 9.4 13.8 9.1 6.7 13.8 2.4 1 1 0 1 1 1 0 DnaJ central domain Yip1 PF04893.17 KFO99332.1 - 8.2e-06 25.6 12.6 1.4e-05 24.9 12.6 1.5 1 0 0 1 1 1 1 Yip1 domain GTP_EFTU PF00009.27 KFO99333.1 - 3.9e-53 179.9 0.2 5.8e-53 179.3 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KFO99333.1 - 2.2e-47 159.6 0.6 1.1e-46 157.3 0.5 2.2 2 0 0 2 2 2 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KFO99333.1 - 9e-20 70.5 0.0 3.5e-19 68.6 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFO99333.1 - 8.5e-08 32.5 0.3 2.3e-07 31.1 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.22 KFO99333.1 - 1.9e-06 27.5 0.0 3.3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KFO99333.1 - 8.4e-06 25.8 0.1 1.7e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 KFO99333.1 - 9.8e-06 25.6 0.0 3.2e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 KFO99333.1 - 2.4e-05 24.2 0.0 4.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 KFO99333.1 - 0.0025 17.3 0.0 0.0072 15.8 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 KFO99333.1 - 0.0076 16.3 0.1 0.021 14.8 0.1 1.8 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Septin PF00735.18 KFO99333.1 - 0.036 13.3 0.9 0.17 11.1 0.0 2.1 2 0 0 2 2 2 0 Septin Glucosamine_iso PF01182.20 KFO99334.1 - 8.2e-21 74.9 0.0 1.2e-20 74.4 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Neur_chan_memb PF02932.16 KFO99335.1 - 4.3e-40 138.3 3.2 1.8e-35 123.2 0.7 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFO99335.1 - 4.4e-37 127.6 1.8 5.6e-37 127.3 1.8 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.23 KFO99336.1 - 5.6e-50 169.8 0.0 8.2e-50 169.2 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFO99336.1 - 5.4e-38 131.4 7.8 7.7e-31 108.0 5.6 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region CytochromB561_N PF09786.9 KFO99336.1 - 0.067 12.2 2.0 0.092 11.7 2.0 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF5522 PF17653.1 KFO99336.1 - 0.11 12.5 0.1 0.32 11.0 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5522) Neur_chan_LBD PF02931.23 KFO99337.1 - 5.1e-43 147.0 0.0 7.3e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFO99337.1 - 6.3e-43 147.5 0.9 9.7e-43 146.9 0.9 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF3695 PF12494.8 KFO99337.1 - 0.018 14.9 0.2 8.6 6.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3695) DUF4396 PF14342.6 KFO99337.1 - 0.12 12.7 7.6 1.2 9.5 2.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4396) COMM_domain PF07258.14 KFO99338.1 - 8.4e-17 61.1 1.7 1.4e-16 60.3 1.7 1.3 1 0 0 1 1 1 1 COMM domain TetR_C_23 PF17931.1 KFO99338.1 - 0.0076 16.4 0.1 0.012 15.7 0.1 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain MgtE_N PF03448.17 KFO99338.1 - 0.0083 16.7 0.3 0.11 13.2 0.0 2.2 2 0 0 2 2 2 1 MgtE intracellular N domain HOIP-UBA PF16678.5 KFO99338.1 - 0.013 15.5 0.7 0.019 15.0 0.3 1.6 2 0 0 2 2 2 0 HOIP UBA domain pair DUF1542 PF07564.11 KFO99338.1 - 2.3 8.4 8.8 0.72 10.0 3.7 2.3 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1542) PhoLip_ATPase_C PF16212.5 KFO99339.1 - 2.1e-78 263.5 29.7 2.1e-78 263.5 29.7 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFO99339.1 - 5.4e-23 80.5 2.8 5.4e-23 80.5 2.8 2.1 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFO99339.1 - 2.7e-12 47.4 0.0 2.6e-06 27.9 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFO99339.1 - 1.5e-10 41.0 0.0 8.7e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFO99339.1 - 5e-07 29.4 0.1 2.1e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFO99339.1 - 0.0064 16.3 0.2 0.0064 16.3 0.2 2.7 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase 23S_rRNA_IVP PF05635.11 KFO99339.1 - 0.12 12.7 0.1 0.53 10.6 0.0 2.1 2 0 0 2 2 2 0 23S rRNA-intervening sequence protein Trypsin PF00089.26 KFO99340.1 - 6.8e-63 212.4 0.1 1.4e-62 211.4 0.1 1.6 1 0 0 1 1 1 1 Trypsin Ldl_recept_a PF00057.18 KFO99340.1 - 2.4e-58 194.0 157.4 1.2e-11 44.6 7.3 10.0 10 1 0 10 10 10 7 Low-density lipoprotein receptor domain class A Fz PF01392.22 KFO99340.1 - 7.8e-45 152.1 15.2 2.5e-26 92.4 6.0 5.7 3 1 2 5 5 5 2 Fz domain Trypsin_2 PF13365.6 KFO99340.1 - 2.7e-07 31.6 0.0 4.5e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFO99340.1 - 0.048 14.0 0.5 0.17 12.3 0.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) zf-NF-X1 PF01422.17 KFO99341.1 - 1e-13 51.0 104.6 1.2e-05 25.2 14.7 17.8 18 1 0 18 18 18 11 NF-X1 type zinc finger Ion_trans PF00520.31 KFO99342.1 - 5.9e-33 114.1 12.0 8.8e-33 113.5 12.0 1.2 1 0 0 1 1 1 1 Ion transport protein CLZ PF16526.5 KFO99342.1 - 3.9e-28 97.6 5.9 4.5e-28 97.4 4.7 1.8 2 0 0 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels cNMP_binding PF00027.29 KFO99342.1 - 2e-19 69.5 0.0 3.3e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KFO99342.1 - 0.0061 16.5 3.3 0.049 13.6 4.2 2.2 2 0 0 2 2 2 1 Ion channel Occludin_ELL PF07303.13 KFO99342.1 - 7.7 7.3 6.9 5.4 7.8 0.1 2.7 3 0 0 3 3 3 0 Occludin homology domain Mg_trans_NIPA PF05653.14 KFO99343.1 - 8.1e-131 435.5 14.6 9.7e-131 435.2 14.6 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KFO99343.1 - 9.8e-09 35.5 5.2 9.8e-09 35.5 5.2 4.2 2 2 2 4 4 4 2 EamA-like transporter family Deltameth_res PF16020.5 KFO99343.1 - 0.048 13.5 2.6 4.3 7.3 0.0 3.1 2 1 0 2 2 2 0 Deltamethrin resistance DUF5392 PF17370.2 KFO99343.1 - 0.26 11.4 2.6 0.41 10.7 1.6 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5392) Pkinase_Tyr PF07714.17 KFO99344.1 - 3.7e-94 314.8 0.2 4.4e-94 314.6 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO99344.1 - 1.8e-47 161.9 0.0 2.2e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFO99344.1 - 0.00013 22.0 1.0 0.0003 20.8 1.0 1.7 1 0 0 1 1 1 1 SH2 domain Haspin_kinase PF12330.8 KFO99344.1 - 0.024 13.6 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KFO99344.1 - 0.035 14.0 0.0 0.076 12.9 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KFO99345.1 - 3.7e-95 318.1 0.1 5.2e-95 317.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO99345.1 - 2.6e-46 158.1 0.0 3.9e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFO99345.1 - 4.7e-19 68.3 0.1 1.3e-18 66.9 0.1 1.8 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFO99345.1 - 3.3e-16 58.6 0.2 1.4e-15 56.6 0.2 2.1 2 0 0 2 2 2 1 SH3 domain PH PF00169.29 KFO99345.1 - 1.9e-15 57.2 0.9 1.1e-14 54.8 0.2 2.2 2 0 0 2 2 2 1 PH domain BTK PF00779.19 KFO99345.1 - 1.4e-12 47.2 1.9 3e-12 46.1 1.9 1.6 1 0 0 1 1 1 1 BTK motif SH3_9 PF14604.6 KFO99345.1 - 2.5e-10 40.1 0.1 5.1e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFO99345.1 - 5.3e-08 32.4 0.0 1.3e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFO99345.1 - 0.00045 20.4 1.7 0.0079 16.5 0.9 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain hSH3 PF14603.6 KFO99345.1 - 0.0039 17.6 0.0 0.015 15.7 0.0 2.0 1 0 0 1 1 1 1 Helically-extended SH3 domain SH3_10 PF17902.1 KFO99345.1 - 0.02 15.0 0.0 0.051 13.6 0.0 1.7 1 0 0 1 1 1 0 SH3 domain SH3_4 PF06347.13 KFO99345.1 - 0.075 12.9 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain Kinase-like PF14531.6 KFO99345.1 - 0.076 12.3 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Kinase-like SLAIN PF15301.6 KFO99346.1 - 6.9e-170 566.0 39.8 7.7e-170 565.8 39.8 1.0 1 0 0 1 1 1 1 SLAIN motif-containing family SBF PF01758.16 KFO99347.1 - 4.9e-24 85.1 12.3 4.9e-24 85.1 12.3 2.0 2 1 1 3 3 3 1 Sodium Bile acid symporter family DUF3392 PF11872.8 KFO99347.1 - 0.031 14.5 7.0 1.3 9.3 3.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3392) zf-3CxxC PF13695.6 KFO99348.1 - 0.0042 17.5 10.7 0.0052 17.2 10.7 1.2 1 0 0 1 1 1 1 Zinc-binding domain FYVE_2 PF02318.16 KFO99348.1 - 1.6 9.0 11.2 1.7 8.9 11.2 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger zf-3CxxC_2 PF17180.4 KFO99348.1 - 2.2 9.1 13.9 7.6 7.4 13.9 2.1 1 1 0 1 1 1 0 Zinc-binding domain Zn_clus PF00172.18 KFO99348.1 - 4.2 7.6 20.0 1.9 8.7 13.7 2.6 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MOR2-PAG1_N PF14222.6 KFO99349.1 - 1.3e-174 582.2 4.7 2.2e-174 581.5 4.7 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KFO99349.1 - 2.9e-74 250.1 5.3 2.9e-74 250.1 5.3 3.7 4 0 0 4 4 4 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KFO99349.1 - 8.5e-36 123.1 14.9 3.1e-14 51.7 0.2 6.1 6 0 0 6 6 6 6 Cell morphogenesis central region OCIA PF07051.11 KFO99350.1 - 1.2e-27 95.7 0.1 2e-27 95.0 0.1 1.4 1 0 0 1 1 1 1 Ovarian carcinoma immunoreactive antigen (OCIA) OCIA PF07051.11 KFO99351.1 - 8.6e-31 105.8 0.1 9.2e-31 105.7 0.1 1.0 1 0 0 1 1 1 1 Ovarian carcinoma immunoreactive antigen (OCIA) GLTT PF01744.20 KFO99351.1 - 0.039 13.7 0.1 0.069 12.9 0.1 1.4 1 0 0 1 1 1 0 GLTT repeat (6 copies) Cullin_binding PF03556.15 KFO99352.1 - 2.3e-31 108.7 0.6 4e-31 108.0 0.6 1.4 1 0 0 1 1 1 1 Cullin binding LRR_8 PF13855.6 KFO99353.1 - 3.2e-25 87.7 20.0 8.4e-16 57.5 1.6 4.1 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KFO99353.1 - 1.7e-13 50.5 30.2 4.1e-06 27.0 4.3 5.5 4 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFO99353.1 - 9e-09 35.4 4.5 1.8e-08 34.4 0.6 2.3 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFO99353.1 - 2.6e-06 27.2 23.9 0.13 12.8 0.6 6.9 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_9 PF14580.6 KFO99353.1 - 1.5e-05 24.6 8.5 0.0028 17.2 1.3 2.3 1 1 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 KFO99353.1 - 0.0021 17.9 22.0 3.6 7.9 0.1 7.1 7 0 0 7 7 7 4 Leucine Rich repeat PI-TkoII_IV PF18714.1 KFO99353.1 - 0.082 12.4 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV Sarcoglycan_1 PF04790.13 KFO99354.1 - 1.1e-63 215.1 0.2 1.3e-63 214.8 0.2 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein MIEAP PF16026.5 KFO99355.1 - 2.3e-58 197.7 0.0 2.6e-58 197.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondria-eating protein UCH PF00443.29 KFO99356.1 - 2.3e-60 204.2 6.4 2.7e-60 204.0 6.4 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFO99356.1 - 7.3e-30 104.6 10.8 1e-29 104.2 10.8 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KFO99356.1 - 5.4e-05 22.8 14.8 0.00024 20.7 12.3 2.1 2 0 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF3399 PF11879.8 KFO99356.1 - 0.4 11.0 8.7 0.84 10.0 8.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3399) NapB PF03892.14 KFO99356.1 - 3.1 7.8 7.6 7.8 6.5 7.6 1.7 1 1 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) Ras PF00071.22 KFO99357.1 - 7.5e-18 64.7 0.0 1e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 KFO99357.1 - 0.0066 16.4 0.1 0.034 14.1 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KFO99357.1 - 0.011 15.9 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFO99357.1 - 0.019 14.5 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain IZUMO PF15005.6 KFO99358.1 - 0.15 12.6 0.7 0.36 11.4 0.3 1.8 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated PKS_DE PF18369.1 KFO99358.1 - 0.33 11.5 1.6 2.3 8.8 0.5 2.8 3 0 0 3 3 3 0 Polyketide synthase dimerisation element domain Fip1 PF05182.13 KFO99359.1 - 1.8e-25 88.1 2.1 4.5e-25 86.9 2.1 1.7 1 0 0 1 1 1 1 Fip1 motif PDZ PF00595.24 KFO99360.1 - 1.3e-60 201.7 3.2 1.1e-17 64.1 0.0 4.2 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 KFO99360.1 - 1.8e-31 107.8 1.0 9.3e-09 35.0 0.0 4.4 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 KFO99360.1 - 4.6e-16 58.9 0.1 0.0052 17.1 0.0 4.3 4 0 0 4 4 4 4 PDZ domain zf-C3HC4 PF00097.25 KFO99360.1 - 1.8e-06 27.7 6.9 5.5e-06 26.1 6.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFO99360.1 - 2.8e-06 27.0 9.0 9.2e-06 25.4 9.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFO99360.1 - 5.1e-06 26.4 7.6 1.4e-05 25.0 7.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFO99360.1 - 1.2e-05 25.5 5.9 1.2e-05 25.5 5.9 2.3 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.6 KFO99360.1 - 3.6e-05 23.6 5.1 0.00014 21.7 5.1 2.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFO99360.1 - 0.0001 22.3 6.8 0.00036 20.6 6.8 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KFO99360.1 - 0.00019 21.2 2.3 0.00019 21.2 2.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFO99360.1 - 0.0015 18.7 3.5 0.0064 16.7 3.5 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain DZR PF12773.7 KFO99360.1 - 0.1 12.6 2.9 0.47 10.5 2.9 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-Nse PF11789.8 KFO99360.1 - 2.3 8.1 5.6 5.9 6.8 5.6 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Yae1_N PF09811.9 KFO99361.1 - 1.2e-17 63.3 61.8 1.8e+04 -26.7 61.8 5.9 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Pkinase_Tyr PF07714.17 KFO99362.1 - 4.3e-104 347.4 0.0 6.4e-104 346.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO99362.1 - 3.4e-42 144.6 0.0 3.1e-30 105.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.6 KFO99362.1 - 6.9e-29 100.3 7.6 4.4e-08 33.6 0.1 5.5 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 KFO99362.1 - 1.4e-23 82.7 3.2 6.9e-09 35.7 0.0 5.8 5 1 1 6 6 6 4 Immunoglobulin I-set domain ig PF00047.25 KFO99362.1 - 8.2e-18 64.4 7.9 6.1e-09 35.9 0.2 4.9 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFO99362.1 - 6.4e-12 45.6 7.2 0.00018 21.8 0.1 5.1 5 0 0 5 5 5 3 Immunoglobulin domain V-set PF07686.17 KFO99362.1 - 2.3e-08 34.2 8.8 0.39 10.9 0.1 6.8 5 2 1 6 6 6 3 Immunoglobulin V-set domain Ig_6 PF18452.1 KFO99362.1 - 0.00022 20.7 0.7 0.77 9.4 0.0 3.6 3 0 0 3 3 3 1 Immunoglobulin domain C2-set_2 PF08205.12 KFO99362.1 - 0.0024 17.9 0.2 2.3 8.3 0.0 3.0 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain APH PF01636.23 KFO99362.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KFO99363.1 - 2.4e-106 354.8 0.0 3.1e-106 354.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO99363.1 - 6.7e-43 147.0 0.0 2.7e-30 105.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.6 KFO99363.1 - 2.8e-26 91.9 1.1 2.1e-14 53.8 0.1 3.4 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFO99363.1 - 1.3e-23 82.9 0.1 5.3e-15 55.2 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain VEGFR-2_TMD PF17988.1 KFO99363.1 - 1.1e-18 66.3 4.7 2.2e-18 65.4 4.7 1.6 1 0 0 1 1 1 1 VEGFR-2 Transmembrane domain Ig_2 PF13895.6 KFO99363.1 - 2.3e-18 66.3 1.5 1.7e-10 41.0 0.0 3.7 3 1 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFO99363.1 - 1.3e-17 63.7 0.5 2.2e-10 40.5 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 KFO99363.1 - 2e-06 27.9 0.5 1 9.6 0.0 4.3 3 2 0 3 3 3 2 Immunoglobulin V-set domain Izumo-Ig PF16706.5 KFO99363.1 - 2.8e-05 24.1 0.3 1.3 9.1 0.0 3.7 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 KFO99363.1 - 0.00039 20.4 0.1 0.0013 18.7 0.0 1.9 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFO99363.1 - 0.011 16.0 0.5 1.6 9.1 0.0 3.1 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain Haspin_kinase PF12330.8 KFO99363.1 - 0.028 13.3 1.1 0.036 13.0 0.1 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Ehrlichia_rpt PF09528.10 KFO99363.1 - 1.1 8.8 4.6 0.49 9.9 1.1 2.2 2 0 0 2 2 2 0 Ehrlichia tandem repeat (Ehrlichia_rpt) Steroid_dh PF02544.16 KFO99364.1 - 3.7e-22 78.9 6.8 4.8e-22 78.5 5.8 1.5 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase FB_lectin PF07367.11 KFO99364.1 - 0.029 14.3 0.1 0.05 13.5 0.1 1.3 1 0 0 1 1 1 0 Fungal fruit body lectin SPC25 PF06703.11 KFO99364.1 - 1.1 9.0 5.2 1.1 9.0 0.8 2.5 2 1 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) UPF0016 PF01169.19 KFO99365.1 - 2e-45 153.0 19.6 4.7e-23 81.3 3.3 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 NMU PF02070.15 KFO99366.1 - 8.4e-09 35.2 2.3 8.4e-09 35.2 2.3 1.9 2 0 0 2 2 2 1 Neuromedin U Sec3_C PF09763.9 KFO99367.1 - 2.5e-179 598.0 27.2 3.2e-179 597.7 27.2 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KFO99367.1 - 1.3e-26 92.5 1.8 4.4e-26 90.8 1.8 2.0 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH FlaC_arch PF05377.11 KFO99367.1 - 0.038 14.4 4.5 0.22 12.0 1.8 3.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DASH_Duo1 PF08651.10 KFO99367.1 - 0.86 9.4 4.8 1 9.2 0.8 3.2 3 0 0 3 3 3 0 DASH complex subunit Duo1 Csm2_III-A PF03750.13 KFO99367.1 - 0.9 10.4 6.9 0.59 11.0 2.2 3.1 2 0 0 2 2 2 0 Csm2 Type III-A GATase_6 PF13522.6 KFO99368.1 - 4.5e-15 56.0 0.0 9.5e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KFO99368.1 - 7.2e-13 48.5 0.0 1.2e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KFO99368.1 - 8.4e-08 31.9 0.0 1.3e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KFO99368.1 - 1.3e-06 27.5 0.0 2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 KFO99368.1 - 0.0072 15.1 0.0 0.011 14.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PRTase_2 PF15609.6 KFO99368.1 - 0.16 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase UPRTase PF14681.6 KFO99368.1 - 0.18 11.2 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Myb_DNA-bind_4 PF13837.6 KFO99369.1 - 6.2e-19 68.2 1.5 8.2e-19 67.8 1.5 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 KFO99369.1 - 0.0021 18.2 1.8 0.004 17.3 1.8 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFO99369.1 - 0.023 15.0 1.9 0.066 13.5 1.9 1.7 1 1 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 KFO99369.1 - 0.033 14.2 3.7 0.18 11.9 3.7 2.0 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain SAICAR_synt PF01259.18 KFO99370.1 - 6.2e-55 186.5 0.1 8.7e-55 186.1 0.1 1.2 1 0 0 1 1 1 1 SAICAR synthetase AIRC PF00731.20 KFO99370.1 - 3e-39 133.9 0.0 5.2e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 AIR carboxylase LON_substr_bdg PF02190.16 KFO99371.1 - 3e-27 95.9 0.0 5.8e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KFO99371.1 - 1.7e-09 37.3 14.3 5.1e-09 35.8 14.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFO99371.1 - 3.1e-09 36.5 8.3 8.5e-09 35.1 8.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFO99371.1 - 2e-07 30.9 8.6 2e-07 30.9 8.6 2.8 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFO99371.1 - 2.3e-07 30.6 12.4 6.7e-07 29.1 12.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFO99371.1 - 5.4e-07 29.8 13.1 1.6e-06 28.3 13.1 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFO99371.1 - 6.9e-06 25.9 12.2 1.7e-05 24.7 12.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFO99371.1 - 1.8e-05 24.5 9.9 3.8e-05 23.5 9.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 TPR_2 PF07719.17 KFO99371.1 - 5.3e-05 23.0 0.0 0.041 14.0 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat zf-C3HC4_4 PF15227.6 KFO99371.1 - 5.3e-05 23.3 11.9 0.00019 21.5 11.9 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KFO99371.1 - 6.7e-05 23.0 6.5 0.00017 21.6 6.5 1.7 1 0 0 1 1 1 1 zinc RING finger of MSL2 U-box PF04564.15 KFO99371.1 - 0.0012 18.9 0.0 0.0033 17.6 0.0 1.6 1 0 0 1 1 1 1 U-box domain NARP1 PF12569.8 KFO99371.1 - 0.0043 16.0 0.0 0.007 15.3 0.0 1.2 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_1 PF00515.28 KFO99371.1 - 0.0082 15.9 0.2 7.8 6.5 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat zf-rbx1 PF12678.7 KFO99371.1 - 0.012 15.9 9.2 0.034 14.4 9.2 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KFO99371.1 - 0.026 14.3 5.0 0.084 12.7 5.0 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KFO99371.1 - 0.072 13.0 6.6 0.18 11.7 6.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_5 PF17121.5 KFO99371.1 - 0.64 9.9 5.9 1.8 8.5 5.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 KFO99371.1 - 1.7 8.6 5.7 1.8 8.5 4.2 1.8 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Methyltransf_11 PF08241.12 KFO99372.1 - 1.7e-14 54.2 0.0 3.6e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFO99372.1 - 6.8e-14 52.3 0.0 2e-13 50.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFO99372.1 - 2.8e-07 30.4 0.1 6.2e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFO99372.1 - 6e-07 29.4 0.1 2.4e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFO99372.1 - 4.5e-06 27.3 0.0 1.8e-05 25.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFO99372.1 - 4.6e-05 22.9 0.0 0.00017 21.0 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 KFO99372.1 - 5.3e-05 23.2 0.0 8.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.20 KFO99372.1 - 0.00032 20.1 0.1 0.0073 15.6 0.1 2.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KFO99372.1 - 0.032 13.1 0.0 0.36 9.7 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) PCMT PF01135.19 KFO99372.1 - 0.21 11.3 0.1 1 9.0 0.1 1.9 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) START PF01852.19 KFO99373.1 - 4.5e-49 166.7 0.0 8.4e-49 165.8 0.0 1.4 1 0 0 1 1 1 1 START domain RhoGAP PF00620.27 KFO99373.1 - 2.3e-41 141.1 0.6 1e-40 139.1 0.8 2.0 2 0 0 2 2 2 1 RhoGAP domain Pox_A28 PF04584.14 KFO99374.1 - 0.051 13.8 0.0 0.066 13.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A28 family Sarcoglycan_1 PF04790.13 KFO99375.1 - 2.7e-87 292.4 0.0 3.1e-87 292.2 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2345 PF10106.9 KFO99375.1 - 2.5e-05 24.2 0.1 0.0019 18.1 0.0 2.6 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2345) OST3_OST6 PF04756.13 KFO99376.1 - 3.1e-112 374.7 0.1 3.5e-112 374.5 0.1 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 KFO99376.1 - 2.5e-05 24.2 0.0 3.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin YhhN PF07947.14 KFO99376.1 - 0.083 12.5 3.2 0.35 10.5 3.2 1.9 1 1 0 1 1 1 0 YhhN family Gram_pos_anchor PF00746.21 KFO99376.1 - 0.1 12.5 0.4 0.1 12.5 0.4 2.1 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF4131 PF13567.6 KFO99376.1 - 0.54 9.9 4.7 0.48 10.1 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) FGF PF00167.18 KFO99377.1 - 1.4e-32 112.4 0.0 1.6e-32 112.2 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor EF-hand_8 PF13833.6 KFO99378.1 - 3.6e-16 58.7 9.7 6.1e-08 32.4 0.0 5.9 6 1 0 6 6 6 2 EF-hand domain pair EF-hand_7 PF13499.6 KFO99378.1 - 3.3e-13 49.9 13.4 2.1e-05 24.9 0.0 5.4 4 3 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 KFO99378.1 - 2.4e-10 39.5 10.4 0.00041 20.1 0.5 6.3 9 0 0 9 9 9 2 EF-hand domain EF-hand_1 PF00036.32 KFO99378.1 - 3.5e-09 35.5 20.6 0.0001 21.6 0.6 6.9 8 0 0 8 8 8 2 EF hand EF-hand_4 PF12763.7 KFO99378.1 - 0.011 15.7 1.2 0.15 12.0 0.1 3.1 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 KFO99378.1 - 0.13 11.9 11.8 2.7 7.6 0.2 5.1 6 0 0 6 6 6 0 EF hand DUF4734 PF15881.5 KFO99378.1 - 0.27 11.4 1.2 22 5.3 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4734) DHHC PF01529.20 KFO99379.1 - 1.3e-35 122.4 14.2 1.3e-35 122.4 14.2 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase Spt4 PF06093.13 KFO99379.1 - 1.3 9.2 6.8 2.4 8.3 6.8 1.4 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger CAF1 PF04857.20 KFO99380.1 - 6.6e-23 81.4 0.8 9.2e-12 44.7 0.1 2.5 1 1 1 2 2 2 2 CAF1 family ribonuclease Mod_r PF07200.13 KFO99381.1 - 1.1e-38 132.6 15.3 1.5e-38 132.2 15.3 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein UEV PF05743.13 KFO99381.1 - 0.0003 20.7 5.1 0.0019 18.1 0.9 2.9 3 0 0 3 3 3 1 UEV domain Tropomyosin_1 PF12718.7 KFO99381.1 - 1.2 9.3 13.4 0.19 11.9 9.2 1.7 1 1 0 1 1 1 0 Tropomyosin like UPF0242 PF06785.11 KFO99381.1 - 2.1 8.4 13.3 4.4 7.4 13.3 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Myotub-related PF06602.14 KFO99382.1 - 1.2e-146 488.3 0.1 1.6e-146 487.8 0.1 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 KFO99382.1 - 0.00073 19.4 0.1 0.0024 17.8 0.0 1.8 2 0 0 2 2 2 1 GRAM domain DSPc PF00782.20 KFO99382.1 - 0.0013 18.5 0.2 0.004 17.0 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFO99382.1 - 0.0064 16.1 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFO99382.1 - 0.019 15.0 0.0 0.038 14.0 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Vps36_ESCRT-II PF11605.8 KFO99382.1 - 0.049 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 AA_permease_2 PF13520.6 KFO99383.1 - 8.4e-53 179.7 26.3 8.4e-53 179.7 26.3 2.2 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 KFO99383.1 - 2.2e-34 118.9 24.9 2.2e-34 118.9 24.9 2.0 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 KFO99383.1 - 1.4e-24 85.9 6.6 1.4e-24 85.9 6.6 3.9 4 0 0 4 4 4 1 C-terminus of AA_permease MAP17 PF15807.5 KFO99383.1 - 0.26 11.5 1.7 0.66 10.2 1.7 1.6 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 UPF0014 PF03649.13 KFO99383.1 - 3.2 7.0 15.6 0.064 12.6 5.3 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0014) Ig_3 PF13927.6 KFO99384.1 - 5.6e-18 65.3 1.1 8.6e-09 35.9 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFO99384.1 - 3.1e-15 56.1 0.8 2.3e-06 27.7 0.0 3.7 3 1 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFO99384.1 - 2.1e-14 53.4 0.2 1.6e-07 31.3 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFO99384.1 - 9.8e-11 41.8 2.7 9.2e-05 22.7 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFO99384.1 - 0.00036 20.7 1.1 3.5 7.9 0.5 3.6 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_6 PF18452.1 KFO99384.1 - 0.0017 17.8 0.1 0.055 13.0 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFO99384.1 - 0.03 14.4 0.1 8.1 6.6 0.0 2.5 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain zf-CCCH_3 PF15663.5 KFO99386.1 - 0.18 12.1 1.9 4.1 7.7 1.1 2.2 2 0 0 2 2 2 0 Zinc-finger containing family Fibrinogen_C PF00147.18 KFO99387.1 - 2.7e-78 262.8 14.1 3.4e-78 262.4 14.1 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PCM1_C PF15717.5 KFO99388.1 - 3.1e-268 891.7 47.2 3.1e-268 891.7 47.2 7.1 4 2 1 6 6 6 1 Pericentriolar material 1 C terminus TFIIE_alpha PF02002.17 KFO99389.1 - 1.7e-28 98.6 0.9 3.7e-28 97.4 0.9 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 KFO99389.1 - 4.2e-21 75.0 2.0 4.2e-21 75.0 2.0 2.3 2 0 0 2 2 2 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.12 KFO99389.1 - 1.2e-06 27.9 0.8 2.6e-06 26.8 0.8 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Elf1 PF05129.13 KFO99389.1 - 0.028 14.5 0.7 0.08 13.0 0.7 1.7 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.11 KFO99389.1 - 0.039 13.9 0.6 0.081 12.9 0.6 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain PyrI_C PF02748.15 KFO99389.1 - 2.2 8.3 5.2 2.7 7.9 3.2 2.2 2 1 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain CBAH PF02275.18 KFO99390.1 - 3.3e-38 132.1 0.1 3.3e-34 119.0 0.0 2.1 1 1 1 2 2 2 2 Linear amide C-N hydrolases, choloylglycine hydrolase family NAAA-beta PF15508.6 KFO99390.1 - 1.9e-21 76.1 0.1 4.6e-21 74.9 0.1 1.7 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase AAT PF03417.16 KFO99390.1 - 0.054 13.2 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase FRG1 PF06229.12 KFO99391.1 - 1.7e-80 269.3 1.3 1.7e-80 269.3 1.3 1.5 2 0 0 2 2 2 1 FRG1-like domain Fascin PF06268.13 KFO99391.1 - 4.6e-08 33.3 0.0 2.2e-07 31.1 0.0 2.1 3 0 0 3 3 3 1 Fascin domain DUF569 PF04601.13 KFO99391.1 - 0.00029 20.5 0.2 0.0036 17.0 0.0 2.8 1 1 0 2 2 2 1 Domain of unknown function (DUF569) Jak1_Phl PF17887.1 KFO99391.1 - 0.087 12.8 0.1 0.087 12.8 0.1 2.2 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain RVT_1 PF00078.27 KFO99393.1 - 0.15 11.6 0.0 0.37 10.3 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Cadherin PF00028.17 KFO99394.1 - 0 1677.4 100.5 7.1e-24 84.1 0.2 34.3 34 0 0 34 34 34 34 Cadherin domain Laminin_G_2 PF02210.24 KFO99394.1 - 7.2e-28 97.7 0.4 4e-27 95.3 0.4 2.5 1 0 0 1 1 1 1 Laminin G domain Cadherin_3 PF16184.5 KFO99394.1 - 2e-23 82.5 62.3 0.0069 16.4 0.1 20.2 22 0 0 22 22 22 7 Cadherin-like Laminin_G_1 PF00054.23 KFO99394.1 - 5.3e-19 68.7 0.0 2.3e-18 66.7 0.0 2.2 1 0 0 1 1 1 1 Laminin G domain Cadherin_2 PF08266.12 KFO99394.1 - 3.5e-18 65.2 3.6 2.2 8.2 0.0 17.6 23 0 0 23 23 20 1 Cadherin-like RET_CLD1 PF17756.1 KFO99394.1 - 4.8e-13 49.5 0.3 4.8 7.5 0.0 11.3 10 2 2 12 12 11 2 RET Cadherin like domain 1 EGF PF00008.27 KFO99394.1 - 6.2e-10 39.2 56.6 0.00012 22.3 7.4 4.8 5 0 0 5 5 4 3 EGF-like domain Cadherin_pro PF08758.11 KFO99394.1 - 2.4e-09 37.2 0.7 2.5 8.3 0.0 12.0 13 0 0 13 13 11 1 Cadherin prodomain like EGF_CA PF07645.15 KFO99394.1 - 5.9e-06 26.4 10.1 5.9e-06 26.4 10.1 4.5 4 0 0 4 4 4 1 Calcium-binding EGF domain Y_Y_Y PF07495.13 KFO99394.1 - 9.9e-05 22.2 8.0 23 5.0 0.0 10.7 12 1 0 12 12 12 0 Y_Y_Y domain MBF2 PF15868.5 KFO99394.1 - 0.006 17.1 1.2 24 5.5 0.0 6.9 5 0 0 5 5 5 0 Transcription activator MBF2 Laminin_G_3 PF13385.6 KFO99394.1 - 0.065 13.4 0.1 0.58 10.3 0.1 2.6 2 0 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily hEGF PF12661.7 KFO99394.1 - 0.13 12.9 47.3 0.089 13.5 5.5 5.0 5 0 0 5 5 5 0 Human growth factor-like EGF DUF3324 PF11797.8 KFO99394.1 - 0.16 12.0 1.3 12 5.9 0.1 4.0 3 0 0 3 3 3 0 Protein of unknown function C-terminal (DUF3324) TMEM100 PF16311.5 KFO99394.1 - 0.17 11.5 0.0 0.44 10.1 0.0 1.6 1 0 0 1 1 1 0 Transmembrane protein 100 7tm_1 PF00001.21 KFO99395.1 - 8e-49 166.3 23.4 1.1e-48 165.8 23.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFO99395.1 - 3.7e-10 39.9 26.6 1.2e-09 38.2 26.6 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFO99395.1 - 7.3e-08 32.1 20.1 9.7e-08 31.7 20.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFO99395.1 - 1.6e-05 24.8 18.2 0.00029 20.7 18.2 2.0 1 1 0 1 1 1 1 Olfactory receptor TctB PF07331.11 KFO99395.1 - 0.11 12.8 16.3 1.1 9.6 0.4 3.0 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF4233 PF14017.6 KFO99395.1 - 4 7.8 21.3 0.096 13.0 1.2 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF4233) Trypsin PF00089.26 KFO99396.1 - 1.4e-67 227.7 0.1 2.1e-67 227.2 0.1 1.3 1 0 0 1 1 1 1 Trypsin PAN_1 PF00024.26 KFO99396.1 - 4.8e-29 100.2 32.9 2.3e-08 33.9 0.5 5.0 5 0 0 5 5 5 4 PAN domain PAN_4 PF14295.6 KFO99396.1 - 1e-14 54.1 24.4 0.00026 20.8 2.3 5.6 4 1 1 5 5 5 4 PAN domain Trypsin_2 PF13365.6 KFO99396.1 - 7e-06 27.0 0.0 1.6e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFO99396.1 - 7e-05 23.2 0.1 0.00014 22.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Toxin_9 PF02819.15 KFO99396.1 - 0.18 12.1 4.1 2.9 8.3 0.2 3.6 2 0 0 2 2 2 0 Spider toxin DUF3719 PF12516.8 KFO99397.1 - 5.5e-23 80.4 0.3 8.1e-22 76.7 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3719) SH3_1 PF00018.28 KFO99398.1 - 3.7e-43 144.9 0.4 3.3e-14 52.2 0.0 3.5 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.6 KFO99398.1 - 1e-39 134.2 1.1 1.2e-14 53.9 0.1 4.2 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 KFO99398.1 - 1.4e-30 104.7 0.7 1.7e-14 53.3 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain Sorb PF02208.16 KFO99398.1 - 6.7e-26 89.9 4.0 1.4e-22 79.2 0.3 2.7 2 0 0 2 2 2 2 Sorbin homologous domain DUF4749 PF15936.5 KFO99399.1 - 2.5e-25 89.4 0.1 4.3e-25 88.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4749) PDZ PF00595.24 KFO99399.1 - 9.5e-17 61.1 0.0 2.1e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain LIM PF00412.22 KFO99399.1 - 1.2e-13 51.1 3.4 1.9e-13 50.4 3.4 1.4 1 0 0 1 1 1 1 LIM domain PDZ_6 PF17820.1 KFO99399.1 - 1.8e-08 34.1 0.0 3.3e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFO99399.1 - 0.00057 20.2 0.0 0.0014 18.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Lar_restr_allev PF14354.6 KFO99399.1 - 0.31 11.5 1.8 0.72 10.3 1.8 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar DUF4586 PF15239.6 KFO99400.1 - 1.7e-114 383.1 11.0 1.9e-114 382.9 11.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) Peptidase_C78 PF07910.13 KFO99401.1 - 8.5e-53 179.0 0.1 1.3e-52 178.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family C78 Ank_2 PF12796.7 KFO99402.1 - 1.1e-07 32.3 0.1 1.3e-07 32.1 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFO99402.1 - 4.5e-06 26.9 0.7 0.026 14.9 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KFO99402.1 - 4.6e-06 26.8 0.3 7.7e-05 22.9 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFO99402.1 - 1.8e-05 25.2 0.6 0.037 14.6 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFO99402.1 - 0.02 15.4 0.8 2.6 8.9 0.0 2.7 3 1 0 3 3 3 0 Ankyrin repeat Nexin_C PF08628.12 KFO99403.1 - 2.1e-28 99.1 1.1 7.7e-28 97.3 0.3 2.5 2 0 0 2 2 2 1 Sorting nexin C terminal PXA PF02194.15 KFO99403.1 - 4.9e-26 91.8 6.2 6.4e-26 91.5 0.5 3.3 3 0 0 3 3 3 1 PXA domain RGS PF00615.19 KFO99403.1 - 4.9e-21 75.2 0.9 4.9e-21 75.2 0.9 3.2 3 0 0 3 3 3 1 Regulator of G protein signaling domain PX PF00787.24 KFO99403.1 - 2.6e-18 66.0 0.8 1.2e-17 63.9 0.1 2.6 2 0 0 2 2 2 1 PX domain Isy1 PF06246.12 KFO99403.1 - 0.016 14.8 0.6 0.016 14.8 0.6 2.8 3 0 0 3 3 3 0 Isy1-like splicing family BLOC1_2 PF10046.9 KFO99403.1 - 0.41 11.0 5.4 0.32 11.3 1.4 2.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4199 PF13858.6 KFO99403.1 - 0.73 10.2 1.8 1.2 9.5 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) FAST_2 PF08368.12 KFO99403.1 - 4 8.3 6.0 3 8.7 0.1 3.5 4 0 0 4 4 4 0 FAST kinase-like protein, subdomain 2 Mito_carr PF00153.27 KFO99404.1 - 1.9e-57 191.2 4.0 6.7e-24 83.6 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 KFO99404.1 - 0.048 12.9 0.2 0.38 9.9 0.1 2.0 2 0 0 2 2 2 0 Fuseless HLH PF00010.26 KFO99405.1 - 5.2e-18 64.8 0.3 8.5e-18 64.1 0.3 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 KFO99405.1 - 1.5e-08 34.7 1.5 1.7e-08 34.5 0.3 1.8 3 0 0 3 3 3 1 Hairy Orange CENP-U PF13097.6 KFO99406.1 - 1.3e-47 162.1 13.9 1.3e-47 162.1 13.9 2.1 3 0 0 3 3 3 1 CENP-A nucleosome associated complex (NAC) subunit HisG PF01634.18 KFO99406.1 - 0.008 16.2 0.8 0.014 15.3 0.8 1.4 1 0 0 1 1 1 1 ATP phosphoribosyltransferase Mt_ATP-synt_B PF05405.14 KFO99406.1 - 0.026 14.2 9.6 0.12 12.0 7.8 2.3 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) APG6_N PF17675.1 KFO99406.1 - 0.8 10.2 15.5 0.18 12.3 10.8 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region Leu_zip PF15294.6 KFO99406.1 - 2.9 7.3 18.9 0.099 12.1 10.6 2.4 2 1 1 3 3 3 0 Leucine zipper PIN_8 PF18476.1 KFO99406.1 - 6.4 6.6 12.5 0.66 9.8 5.7 2.1 2 0 0 2 2 2 0 PIN like domain Herpes_UL52 PF03121.15 KFO99407.1 - 2.7e-14 52.9 0.1 7.4e-14 51.5 0.1 1.8 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase DNA_primase_S PF01896.19 KFO99407.1 - 0.03 14.3 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 DNA primase small subunit DUF4853 PF16145.5 KFO99407.1 - 0.053 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4853) IRF PF00605.17 KFO99408.1 - 4.7e-42 142.5 1.0 8.8e-42 141.7 1.0 1.5 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor Heme_oxygenase PF01126.20 KFO99408.1 - 0.082 12.7 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Heme oxygenase Phosphodiest PF01663.22 KFO99409.1 - 2.6e-76 257.6 0.6 3e-76 257.3 0.6 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KFO99409.1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily Sulfatase PF00884.23 KFO99409.1 - 0.014 14.8 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 Sulfatase PglZ PF08665.12 KFO99409.1 - 0.019 15.0 0.4 0.042 14.0 0.0 1.7 2 0 0 2 2 2 0 PglZ domain DUF229 PF02995.17 KFO99409.1 - 0.18 10.3 0.0 0.28 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Stork_head PF10264.9 KFO99410.1 - 8.6e-30 102.7 0.1 1.6e-29 101.8 0.1 1.5 1 0 0 1 1 1 1 Winged helix Storkhead-box1 domain Foie-gras_1 PF11817.8 KFO99411.1 - 3.2e-77 259.6 0.3 5.3e-77 258.9 0.3 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 Gryzun-like PF12742.7 KFO99411.1 - 5.4e-23 80.8 0.1 3.1e-22 78.3 0.0 2.1 2 0 0 2 2 2 1 Gryzun, putative Golgi trafficking Gryzun PF07919.12 KFO99411.1 - 4.1e-12 45.7 0.1 8.6e-10 38.0 0.2 2.2 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi Prefoldin PF02996.17 KFO99411.1 - 0.061 13.2 0.1 0.3 11.0 0.1 2.2 1 0 0 1 1 1 0 Prefoldin subunit RWD PF05773.22 KFO99412.1 - 1.6e-14 54.2 0.1 4.8e-14 52.6 0.0 1.7 2 0 0 2 2 2 1 RWD domain Inhibitor_I71 PF12628.7 KFO99412.1 - 0.0037 17.1 0.4 0.0048 16.8 0.4 1.1 1 0 0 1 1 1 1 Falstatin, cysteine peptidase inhibitor ING PF12998.7 KFO99413.1 - 5.1e-12 46.3 3.8 5.1e-12 46.3 3.8 1.7 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KFO99413.1 - 2.8e-06 27.1 7.6 2.8e-06 27.1 7.6 2.3 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KFO99413.1 - 0.0026 17.3 2.8 0.007 15.9 2.8 1.8 1 0 0 1 1 1 1 PHD-finger zf-RING-like PF08746.11 KFO99413.1 - 0.011 16.0 4.9 0.15 12.4 2.6 2.6 2 0 0 2 2 2 0 RING-like domain zf-HC5HC2H PF13771.6 KFO99413.1 - 0.6 10.4 8.0 0.16 12.2 4.1 2.2 2 1 0 2 2 2 0 PHD-like zinc-binding domain XTBD PF11952.8 KFO99414.1 - 1.3e-08 34.5 0.0 1.7e-06 27.7 0.0 2.5 2 0 0 2 2 2 2 XRN-Two Binding Domain, XTBD PMP22_Claudin PF00822.20 KFO99415.1 - 5.2e-24 85.0 0.8 6.2e-24 84.7 0.8 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFO99415.1 - 1.1e-07 31.9 4.7 2e-06 27.7 4.7 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFO99416.1 - 3.5e-12 46.5 0.1 3.9e-12 46.3 0.1 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFO99416.1 - 0.00028 20.7 0.2 0.00037 20.3 0.2 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction dCMP_cyt_deam_1 PF00383.23 KFO99418.1 - 8.1e-29 99.5 0.2 1.2e-28 99.0 0.2 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFO99418.1 - 9.3e-15 54.6 0.0 1.1e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC3 PF18771.1 KFO99418.1 - 0.021 14.9 0.2 0.049 13.7 0.1 1.7 2 0 0 2 2 2 0 APOBEC3 APOBEC4_like PF18774.1 KFO99418.1 - 0.045 13.7 0.2 0.071 13.1 0.2 1.4 1 1 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase Ten_N PF06484.12 KFO99419.1 - 1.7e-70 238.8 13.0 2.7e-70 238.2 13.0 1.3 1 0 0 1 1 1 1 Teneurin Intracellular Region Tox-GHH PF15636.6 KFO99419.1 - 7.3e-32 109.2 1.3 1.4e-31 108.3 1.3 1.5 1 0 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin EGF_2 PF07974.13 KFO99419.1 - 2.1e-14 53.5 179.4 0.001 19.3 12.3 9.8 10 0 0 10 10 10 8 EGF-like domain RHS_repeat PF05593.14 KFO99419.1 - 2.9e-13 50.0 39.2 0.0025 18.3 0.7 10.9 10 3 2 12 12 12 4 RHS Repeat NHL PF01436.21 KFO99419.1 - 3.2e-08 33.2 3.8 0.046 13.8 0.0 6.1 6 0 0 6 6 6 2 NHL repeat CarboxypepD_reg PF13620.6 KFO99419.1 - 0.028 14.7 0.3 0.24 11.7 0.0 2.8 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain DUF2283 PF10049.9 KFO99419.1 - 0.042 14.1 0.0 4.3 7.7 0.0 3.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2283) EGF_Tenascin PF18720.1 KFO99419.1 - 0.22 11.6 106.1 0.014 15.4 6.4 8.7 8 0 0 8 8 8 0 Tenascin EGF domain I-EGF_1 PF18372.1 KFO99419.1 - 0.68 10.1 115.3 0.071 13.2 4.6 8.9 8 0 0 8 8 8 0 Integrin beta epidermal growth factor like domain 1 Ten_N PF06484.12 KFO99420.1 - 2.2e-35 123.2 4.9 2.4e-35 123.1 4.9 1.0 1 0 0 1 1 1 1 Teneurin Intracellular Region RVT_1 PF00078.27 KFO99421.1 - 0.062 12.8 0.0 0.16 11.5 0.0 1.8 3 0 0 3 3 3 0 Reverse transcriptase (RNA-dependent DNA polymerase) Yae1_N PF09811.9 KFO99422.1 - 5.4e-07 29.2 19.3 0.086 12.6 19.3 2.5 1 1 0 1 1 1 1 Essential protein Yae1, N terminal Asparaginase_2 PF01112.18 KFO99423.1 - 2e-81 273.4 0.5 2.5e-81 273.1 0.5 1.0 1 0 0 1 1 1 1 Asparaginase zf-GRF PF06839.12 KFO99424.1 - 4.6e-37 125.8 29.1 1.5e-19 69.8 2.3 4.2 4 0 0 4 4 4 2 GRF zinc finger H2TH PF06831.14 KFO99424.1 - 1.3e-10 41.1 0.0 2.5e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.24 KFO99424.1 - 0.00044 20.8 0.0 0.001 19.7 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain zf-RanBP PF00641.18 KFO99424.1 - 0.0023 17.2 3.1 0.0023 17.2 3.1 2.5 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others MIT_LIKE_ACTX PF17556.2 KFO99424.1 - 1.6 9.4 7.7 4.2 8.0 0.6 3.2 1 1 2 3 3 3 0 MIT-like atracotoxin family RVT_1 PF00078.27 KFO99425.1 - 0.096 12.2 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PDGF PF00341.17 KFO99426.1 - 7.2e-24 83.9 6.8 7.2e-24 83.9 6.8 3.2 3 0 0 3 3 3 1 PDGF/VEGF domain CXCXC PF03128.14 KFO99426.1 - 1.5e-08 34.5 60.9 0.00052 20.3 5.0 9.0 8 0 0 8 8 8 6 CXCXC repeat PH_16 PF17838.1 KFO99427.1 - 1e-39 135.2 1.9 1.3e-39 134.8 0.5 2.0 2 0 0 2 2 2 1 PH domain RhoGEF PF00621.20 KFO99427.1 - 3.5e-31 108.9 7.2 3.5e-31 108.9 7.2 3.0 3 1 0 3 3 3 1 RhoGEF domain PH PF00169.29 KFO99427.1 - 1.1e-05 25.9 0.1 8.8e-05 23.0 0.0 2.7 2 0 0 2 2 2 1 PH domain C1_1 PF00130.22 KFO99427.1 - 0.00019 21.3 7.3 0.00039 20.3 7.3 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KFO99427.1 - 0.027 14.8 4.5 0.061 13.7 4.5 1.6 1 0 0 1 1 1 0 C1 domain Prok-RING_1 PF14446.6 KFO99427.1 - 0.17 11.8 6.2 0.41 10.6 6.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 KFO99427.1 - 0.22 11.2 6.0 0.45 10.2 6.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type CBF PF03914.17 KFO99427.1 - 1.7 8.6 6.9 0.31 11.1 0.1 3.1 3 0 0 3 3 3 0 CBF/Mak21 family DZR PF12773.7 KFO99427.1 - 3.8 7.6 6.4 14 5.8 6.4 1.9 1 0 0 1 1 1 0 Double zinc ribbon Kelch_1 PF01344.25 KFO99428.1 - 2.8e-51 170.9 9.7 2e-11 43.3 0.1 6.0 6 1 0 6 6 6 5 Kelch motif BACK PF07707.15 KFO99428.1 - 1.9e-33 114.6 3.4 2.2e-33 114.4 1.9 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFO99428.1 - 1.4e-30 104.6 4.3 4.3e-06 26.8 0.0 6.1 3 2 3 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KFO99428.1 - 1.5e-28 98.5 2.0 9.4e-06 25.8 0.0 6.3 6 1 0 6 6 6 5 Galactose oxidase, central domain BTB PF00651.31 KFO99428.1 - 5.6e-26 90.9 0.1 1.2e-25 89.8 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 KFO99428.1 - 2.1e-25 87.7 5.7 0.00019 21.3 0.1 6.3 5 1 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 KFO99428.1 - 1.5e-23 82.5 1.1 6.8e-08 32.4 0.0 5.7 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFO99428.1 - 1.3e-13 50.6 3.0 1.3e-06 28.3 0.0 5.5 5 0 0 5 5 5 2 Kelch motif DUF1668 PF07893.13 KFO99428.1 - 0.0072 15.7 0.2 0.035 13.5 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1668) DUF3342 PF11822.8 KFO99428.1 - 0.0095 16.1 0.0 0.035 14.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) Root_cap PF06830.11 KFO99428.1 - 0.17 12.0 0.0 0.43 10.7 0.0 1.7 1 0 0 1 1 1 0 Root cap Pepdidase_M14_N PF18027.1 KFO99429.1 - 1.4e-10 41.4 0.1 2.9e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 KFO99429.1 - 4.5e-10 39.8 0.0 8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 KFO99429.1 - 0.08 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Neurochondrin PF05536.11 KFO99429.1 - 0.11 10.8 0.0 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 Neurochondrin SCNM1_acidic PF15805.5 KFO99429.1 - 1.3 8.8 7.1 0.65 9.8 3.6 2.3 2 0 0 2 2 2 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 RVT_1 PF00078.27 KFO99430.1 - 0.089 12.3 0.0 6.4 6.2 0.0 2.6 3 0 0 3 3 3 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.17 KFO99431.1 - 1.9e-90 302.6 0.1 3.3e-53 180.6 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFO99431.1 - 1.7e-43 148.9 0.0 3.9e-43 147.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain TPKR_C2 PF16920.5 KFO99431.1 - 2.1e-20 72.6 6.5 6.3e-20 71.0 6.5 1.9 1 0 0 1 1 1 1 Tyrosine-protein kinase receptor C2 Ig-like domain Ig_3 PF13927.6 KFO99431.1 - 1.9e-13 50.8 0.0 2.3e-05 24.9 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFO99431.1 - 4.5e-13 49.1 0.0 1.2e-06 28.5 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFO99431.1 - 9.4e-09 35.3 0.1 0.00014 22.0 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFO99431.1 - 3e-07 30.7 0.1 0.038 14.3 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFO99431.1 - 0.0017 18.4 0.0 0.52 10.4 0.0 2.5 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain TrkA_TMD PF18613.1 KFO99431.1 - 0.0089 15.4 11.6 0.019 14.4 11.6 1.6 1 0 0 1 1 1 1 Tyrosine kinase receptor A trans-membrane domain LRR_8 PF13855.6 KFO99431.1 - 0.014 15.2 1.0 0.027 14.2 1.0 1.5 1 0 0 1 1 1 0 Leucine rich repeat Haspin_kinase PF12330.8 KFO99431.1 - 0.083 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain MRP-L46 PF11788.8 KFO99432.1 - 3.8e-12 47.0 1.7 6.6e-12 46.2 1.7 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 HTH_27 PF13463.6 KFO99432.1 - 0.0037 17.7 0.1 0.0075 16.7 0.1 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain NUDIX PF00293.28 KFO99432.1 - 0.052 13.6 0.1 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 NUDIX domain LapD_MoxY_N PF16448.5 KFO99432.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 LapD/MoxY periplasmic domain Ribosomal_S11 PF00411.19 KFO99433.1 - 9.9e-28 96.7 3.2 1.4e-27 96.2 3.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 Det1 PF09737.9 KFO99434.1 - 3e-189 629.3 0.9 3.6e-189 629.1 0.9 1.1 1 0 0 1 1 1 1 De-etiolated protein 1 Det1 RNase_T PF00929.24 KFO99435.1 - 1.9e-19 70.8 0.0 2.9e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KFO99435.1 - 1.6e-05 24.7 0.0 4.6e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease Xlink PF00193.17 KFO99436.1 - 2.5e-122 399.6 18.0 1.9e-32 111.5 0.4 5.5 5 1 1 6 6 6 4 Extracellular link domain Lectin_C PF00059.21 KFO99436.1 - 1.5e-21 77.1 17.2 1.2e-19 71.1 2.8 5.1 5 0 0 5 5 5 2 Lectin C-type domain Sushi PF00084.20 KFO99436.1 - 1.5e-08 35.1 1.2 4.5e-08 33.6 1.2 1.9 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) V-set PF07686.17 KFO99436.1 - 1.6e-08 34.7 0.0 3.5e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin V-set domain EGF PF00008.27 KFO99436.1 - 7.3e-06 26.2 5.4 7.3e-06 26.2 5.4 2.2 2 0 0 2 2 2 1 EGF-like domain hEGF PF12661.7 KFO99436.1 - 0.00047 20.7 1.8 0.00047 20.7 1.8 2.8 3 0 0 3 3 3 1 Human growth factor-like EGF CTD PF12815.7 KFO99436.1 - 0.032 14.8 22.1 4.7 7.8 0.1 6.7 2 2 4 6 6 6 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Chordopox_A33R PF05966.12 KFO99436.1 - 0.1 11.9 3.3 19 4.4 0.1 4.2 5 0 0 5 5 5 0 Chordopoxvirus A33R protein UL45 PF05473.12 KFO99436.1 - 0.19 11.3 0.8 0.7 9.5 0.8 1.9 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like EGF_CA PF07645.15 KFO99436.1 - 0.2 11.9 8.5 0.47 10.7 7.0 2.6 2 1 0 2 2 2 0 Calcium-binding EGF domain Xlink PF00193.17 KFO99437.1 - 2.1e-41 140.2 0.0 3.2e-33 114.0 0.0 2.3 2 0 0 2 2 2 2 Extracellular link domain V-set PF07686.17 KFO99437.1 - 1.7e-13 50.7 0.0 3.2e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFO99437.1 - 1e-07 32.1 0.0 1.5e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFO99437.1 - 2.7e-06 27.9 0.0 5.7e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFO99437.1 - 1.6e-05 24.9 0.0 3.2e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFO99437.1 - 0.0024 18.2 0.2 0.039 14.3 0.0 2.4 2 1 0 2 2 2 1 Immunoglobulin domain Lectin_C PF00059.21 KFO99437.1 - 0.0037 18.0 0.2 1 10.1 0.0 2.4 2 0 0 2 2 2 1 Lectin C-type domain Izumo-Ig PF16706.5 KFO99437.1 - 0.0045 17.0 0.0 0.0084 16.1 0.0 1.4 1 0 0 1 1 1 1 Izumo-like Immunoglobulin domain V-set_CD47 PF08204.11 KFO99437.1 - 0.017 15.1 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain Abhydrolase_1 PF00561.20 KFO99438.1 - 4.6e-25 88.7 0.0 6.3e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFO99438.1 - 4.7e-11 42.4 0.0 1.1e-10 41.3 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Cutinase PF01083.22 KFO99438.1 - 0.0026 17.8 0.1 0.0058 16.6 0.1 1.6 1 1 0 1 1 1 1 Cutinase DUF2637 PF10935.8 KFO99438.1 - 0.0039 17.1 0.1 0.16 11.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2637) Peptidase_S9 PF00326.21 KFO99438.1 - 0.0087 15.6 0.3 0.43 10.0 0.1 2.8 2 1 1 3 3 3 1 Prolyl oligopeptidase family Palm_thioest PF02089.15 KFO99438.1 - 0.0095 15.8 0.2 0.022 14.6 0.2 1.6 2 0 0 2 2 2 1 Palmitoyl protein thioesterase DUF915 PF06028.11 KFO99438.1 - 0.016 14.6 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) VirJ PF06057.11 KFO99438.1 - 0.048 13.5 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_5 PF12695.7 KFO99438.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 KFO99438.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF5464 PF17552.2 KFO99438.1 - 0.71 10.2 3.5 1 9.7 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5464) CRAL_TRIO PF00650.20 KFO99439.1 - 3.8e-38 130.7 0.1 6.1e-38 130.0 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFO99439.1 - 8e-11 42.2 0.0 1.3e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFO99439.1 - 7.2e-07 29.3 0.4 2.4e-06 27.6 0.4 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF1336 PF07059.12 KFO99439.1 - 0.055 13.5 0.0 0.093 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1336) Spc7 PF08317.11 KFO99439.1 - 0.1 11.5 1.9 0.17 10.7 1.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein FANCI_HD2 PF14680.6 KFO99440.1 - 5.9e-98 326.9 1.8 2.2e-97 325.0 1.8 2.1 1 0 0 1 1 1 1 FANCI helical domain 2 FANCI_S4 PF14678.6 KFO99440.1 - 2.7e-93 311.7 5.7 2.7e-93 311.7 5.7 3.0 4 0 0 4 4 4 1 FANCI solenoid 4 FANCI_S3 PF14677.6 KFO99440.1 - 4.7e-82 274.8 3.2 4.7e-82 274.8 3.2 3.3 3 0 0 3 3 3 1 FANCI solenoid 3 FANCI_S1 PF14675.6 KFO99440.1 - 1.2e-79 267.0 1.3 1.2e-79 267.0 1.3 2.3 2 0 0 2 2 2 1 FANCI solenoid 1 FANCI_S2 PF14676.6 KFO99440.1 - 2.5e-58 197.0 0.2 2.5e-58 197.0 0.2 3.7 4 0 0 4 4 4 1 FANCI solenoid 2 FANCI_HD1 PF14679.6 KFO99440.1 - 6.8e-31 106.1 1.7 1.6e-30 104.9 0.4 2.5 2 0 0 2 2 2 1 FANCI helical domain 1 FANCI_S1-cap PF14674.6 KFO99440.1 - 3.4e-23 81.5 0.8 1.7e-22 79.2 0.8 2.4 1 0 0 1 1 1 1 FANCI solenoid 1 cap DNApol_Exo PF18136.1 KFO99441.1 - 3.9e-107 357.6 0.0 7.3e-107 356.7 0.0 1.5 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KFO99441.1 - 6.1e-60 203.3 0.0 9.9e-60 202.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 KFO99441.1 - 0.051 13.3 0.1 0.38 10.5 0.1 2.2 1 1 0 1 1 1 0 3'-5' exonuclease Ammonium_transp PF00909.21 KFO99442.1 - 1.6e-75 254.3 20.1 2e-75 254.0 20.1 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family DUF4293 PF14126.6 KFO99442.1 - 0.037 14.3 1.3 0.11 12.7 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) Treslin_N PF15292.6 KFO99443.1 - 6.1e-258 858.3 6.0 7e-258 858.1 6.0 1.0 1 0 0 1 1 1 1 Treslin N-terminus Kinesin PF00225.23 KFO99445.1 - 3.9e-78 262.7 0.0 3.9e-78 262.7 0.0 2.9 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KFO99445.1 - 0.0085 16.0 0.0 0.0085 16.0 0.0 3.3 2 0 0 2 2 2 1 Microtubule binding DUF2808 PF10989.8 KFO99445.1 - 1.1 9.2 6.4 0.67 9.9 2.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2808) Ras PF00071.22 KFO99446.1 - 1.2e-18 67.3 0.0 1.3e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO99446.1 - 0.0018 18.5 0.0 0.0021 18.3 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO99446.1 - 0.085 12.3 0.1 0.14 11.6 0.1 1.4 1 1 0 1 1 1 0 ADP-ribosylation factor family Perilipin PF03036.16 KFO99447.1 - 2.1e-53 181.8 0.6 2.3e-53 181.6 0.6 1.0 1 0 0 1 1 1 1 Perilipin family NPV_P10 PF05531.12 KFO99447.1 - 0.058 13.9 0.3 0.16 12.4 0.0 1.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein PEX11 PF05648.14 KFO99448.1 - 3e-61 206.8 0.3 3.3e-61 206.6 0.3 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) UPF0258 PF06789.12 KFO99449.1 - 1.6e-60 203.7 0.2 3.9e-60 202.4 0.2 1.7 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0258) RXT2_N PF08595.11 KFO99449.1 - 0.0021 18.1 0.7 0.0021 18.1 0.7 2.3 3 0 0 3 3 3 1 RXT2-like, N-terminal Alveol-reg_P311 PF11092.8 KFO99449.1 - 0.092 12.9 0.1 0.32 11.2 0.1 1.9 1 0 0 1 1 1 0 Neuronal protein 3.1 (p311) 5-FTHF_cyc-lig PF01812.20 KFO99450.1 - 3.3e-54 183.6 0.0 3.6e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Sel_put PF04328.13 KFO99450.1 - 0.088 12.9 0.0 1 9.5 0.0 2.1 2 0 0 2 2 2 0 Selenoprotein, putative Bcl-2 PF00452.19 KFO99451.1 - 8.6e-23 80.9 0.0 1.3e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family zf-A20 PF01754.16 KFO99452.1 - 8.4e-13 48.0 8.7 2.5e-12 46.5 8.7 1.9 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.16 KFO99452.1 - 3.3e-09 36.8 7.5 3.3e-09 36.8 7.5 2.3 3 1 1 4 4 4 1 AN1-like Zinc finger IQCJ-SCHIP1 PF15157.6 KFO99452.1 - 4.5 7.1 7.0 0.68 9.8 0.8 2.0 1 1 1 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif FAA_hydrolase PF01557.18 KFO99453.1 - 6.9e-57 192.6 0.0 9.3e-57 192.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KFO99453.1 - 4e-34 117.0 0.0 6.5e-34 116.3 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal PAS_3 PF08447.12 KFO99454.1 - 1.7e-24 85.9 0.0 1.5e-18 66.8 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 KFO99454.1 - 1.9e-23 82.6 0.0 9.7e-14 51.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KFO99454.1 - 1.1e-21 77.1 0.6 1.3e-18 67.2 0.2 3.1 2 1 1 3 3 3 2 PAS domain HLH PF00010.26 KFO99454.1 - 3e-14 52.7 1.2 5.8e-14 51.8 1.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 KFO99454.1 - 8.8e-12 45.2 0.0 6.6e-09 36.0 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KFO99454.1 - 4.2e-05 23.8 0.0 0.13 12.5 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.11 KFO99454.1 - 0.015 16.0 0.0 0.19 12.4 0.0 2.3 2 0 0 2 2 2 0 PAS fold Hydrolase_4 PF12146.8 KFO99455.1 - 1.7e-13 50.4 0.0 2.7e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFO99455.1 - 1.3e-07 31.5 0.1 0.0073 16.0 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFO99455.1 - 1.7e-07 32.0 0.0 0.00015 22.4 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KFO99455.1 - 7.7e-07 28.8 0.0 2.7e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family UPF0227 PF05728.12 KFO99455.1 - 0.00068 19.6 0.0 0.014 15.3 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) DLH PF01738.18 KFO99455.1 - 0.00083 19.0 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF818 PF05677.12 KFO99455.1 - 0.0012 17.9 0.1 0.0018 17.3 0.1 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_5 PF12695.7 KFO99455.1 - 0.0025 17.6 0.0 0.0053 16.5 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 KFO99455.1 - 0.0055 16.4 0.0 0.0087 15.7 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Asp2 PF16929.5 KFO99455.1 - 0.0088 15.1 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Accessory Sec system GspB-transporter Abhydrolase_2 PF02230.16 KFO99455.1 - 0.0094 15.8 0.0 0.055 13.3 0.0 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DUF4074 PF13293.6 KFO99455.1 - 0.11 12.8 0.2 0.76 10.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4074) ILEI PF15711.5 KFO99456.1 - 1.8e-40 137.3 1.0 1.9e-23 82.7 0.0 3.3 3 0 0 3 3 3 2 Interleukin-like EMT inducer G8 PF10162.9 KFO99456.1 - 3.5e-28 98.2 0.0 6.9e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 G8 domain Mucin2_WxxW PF13330.6 KFO99456.1 - 5.2e-15 56.0 0.9 5.2e-13 49.6 0.2 2.5 2 0 0 2 2 2 1 Mucin-2 protein WxxW repeating region Beta_helix PF13229.6 KFO99456.1 - 0.019 14.8 1.0 3.7 7.4 0.1 3.5 2 1 0 3 3 3 0 Right handed beta helix region Mesd PF10185.9 KFO99457.1 - 2.5e-67 225.6 0.4 3.1e-67 225.3 0.4 1.2 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor DUF3391 PF11871.8 KFO99457.1 - 0.0067 17.0 0.4 0.0094 16.5 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3391) PSII_BNR PF14870.6 KFO99457.1 - 0.023 14.0 0.0 0.057 12.7 0.0 1.6 1 1 1 2 2 2 0 Photosynthesis system II assembly factor YCF48 PDZ PF00595.24 KFO99460.1 - 3.2e-30 104.3 0.1 2.1e-18 66.5 0.1 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFO99460.1 - 1.1e-16 60.3 0.0 8.7e-09 35.1 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFO99460.1 - 8.5e-08 32.4 0.0 0.0009 19.5 0.0 2.5 2 1 0 2 2 2 2 PDZ domain PDZ_4 PF17816.1 KFO99460.1 - 0.041 14.3 0.0 15 6.0 0.0 2.3 2 0 0 2 2 2 0 PDZ domain START PF01852.19 KFO99461.1 - 2.3e-18 66.4 0.0 2.7e-18 66.1 0.0 1.0 1 0 0 1 1 1 1 START domain TSP_1 PF00090.19 KFO99463.1 - 1.1e-50 169.6 161.3 5.7e-06 26.4 6.2 15.0 14 1 0 14 14 13 12 Thrombospondin type 1 domain I-set PF07679.16 KFO99463.1 - 4.8e-33 113.1 0.0 2.2e-14 53.3 0.0 4.0 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO99463.1 - 3.4e-30 104.5 0.8 1e-11 45.3 0.0 4.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFO99463.1 - 2.2e-22 79.2 0.3 5.4e-10 39.5 0.0 4.6 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 KFO99463.1 - 1.2e-17 63.9 0.1 5.6e-09 36.0 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFO99463.1 - 4.4e-12 46.1 0.3 0.0056 16.8 0.0 4.9 3 1 1 4 4 4 3 Immunoglobulin V-set domain Ig_4 PF16680.5 KFO99463.1 - 1.3e-07 31.8 1.6 0.31 11.3 0.0 4.5 4 0 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFO99463.1 - 0.0009 18.8 0.0 0.72 9.5 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain ADAM_spacer1 PF05986.14 KFO99463.1 - 0.0041 17.2 0.0 0.0088 16.1 0.0 1.5 1 0 0 1 1 1 1 ADAM-TS Spacer 1 PLAC PF08686.11 KFO99463.1 - 0.0061 17.3 4.8 0.049 14.4 4.8 2.8 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Izumo-Ig PF16706.5 KFO99463.1 - 0.034 14.2 0.0 17 5.6 0.0 2.9 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 KFO99463.1 - 0.12 12.4 0.3 0.7 10.0 0.0 2.5 2 0 0 2 2 2 0 C17orf99 Ig domain Filament PF00038.21 KFO99464.1 - 5.3e-78 262.7 53.4 8.1e-78 262.1 53.4 1.4 1 0 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 KFO99464.1 - 4.7e-15 55.9 0.0 8.7e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Lamin Tail Domain Rab5-bind PF09311.11 KFO99464.1 - 5.6 6.3 47.8 1.4 8.2 12.8 3.3 1 1 2 3 3 3 0 Rabaptin-like protein BAR PF03114.18 KFO99465.1 - 4.5e-78 262.2 8.6 5.3e-78 261.9 8.6 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KFO99465.1 - 1e-14 53.9 0.1 3e-14 52.3 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFO99465.1 - 1.5e-13 50.2 0.0 3.9e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFO99465.1 - 2.1e-13 49.9 0.1 3.3e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.9 KFO99465.1 - 1.1e-07 31.3 4.9 5.1e-06 25.8 1.7 2.1 2 0 0 2 2 2 2 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 KFO99465.1 - 0.00079 19.2 8.7 0.0096 15.6 6.5 2.9 1 1 1 2 2 2 1 BAR domain of APPL family PARP_reg PF02877.14 KFO99465.1 - 0.24 11.5 2.9 0.36 10.9 0.7 2.4 2 2 0 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain Csm2_III-A PF03750.13 KFO99465.1 - 0.47 11.3 3.5 0.42 11.5 0.7 2.3 2 0 0 2 2 2 0 Csm2 Type III-A zf-met PF12874.7 KFO99466.1 - 1.1e-08 35.1 21.9 0.0024 18.2 0.1 5.6 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KFO99466.1 - 5.5e-06 26.5 40.8 0.0038 17.6 2.3 7.4 6 1 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO99466.1 - 6.4e-05 23.5 48.9 0.0044 17.7 1.6 8.7 10 0 0 10 10 10 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO99466.1 - 8.4e-05 22.7 23.8 0.011 15.9 1.3 5.0 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding ABC_trans_N PF14510.6 KFO99466.1 - 0.024 15.3 0.5 1.9 9.2 0.1 2.9 2 0 0 2 2 2 0 ABC-transporter N-terminal zf-C2H2_aberr PF17017.5 KFO99466.1 - 1.2 9.3 15.3 1.6 8.9 0.3 4.4 5 0 0 5 5 5 0 Aberrant zinc-finger zf-DNA_Pol PF08996.10 KFO99466.1 - 1.3 8.7 13.7 0.24 11.1 1.2 3.5 3 0 0 3 3 3 0 DNA Polymerase alpha zinc finger zf-BED PF02892.15 KFO99466.1 - 2.9 8.0 14.2 3.6 7.7 0.7 3.9 3 0 0 3 3 3 0 BED zinc finger PWWP PF00855.17 KFO99467.1 - 0.00024 21.4 0.0 0.00024 21.4 0.0 2.4 2 1 0 2 2 2 1 PWWP domain Raftlin PF15250.6 KFO99467.1 - 4.2 6.0 12.2 5.5 5.6 12.2 1.0 1 0 0 1 1 1 0 Raftlin DUF2781 PF10914.8 KFO99468.1 - 3.2e-20 73.0 2.0 3.2e-20 73.0 2.0 3.3 3 2 0 3 3 3 2 Protein of unknown function (DUF2781) PHR PF08005.12 KFO99469.1 - 2.4e-50 171.1 0.8 3.4e-50 170.6 0.8 1.2 1 0 0 1 1 1 1 PHR domain BACK PF07707.15 KFO99469.1 - 8.5e-10 38.7 0.2 1.3e-08 34.8 0.1 2.6 1 1 1 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 KFO99469.1 - 1.1e-06 28.8 0.3 3.5e-05 24.0 0.0 2.5 1 1 1 2 2 2 1 BTB/POZ domain DUF167 PF02594.16 KFO99470.1 - 5.7e-20 71.2 0.9 6.5e-20 71.0 0.9 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 RAM PF15320.6 KFO99471.1 - 8.1e-20 71.2 1.7 8.9e-20 71.1 1.7 1.0 1 0 0 1 1 1 1 mRNA cap methylation, RNMT-activating mini protein WH1 PF00568.23 KFO99472.1 - 3.7e-36 123.4 0.4 7.9e-36 122.4 0.4 1.5 1 0 0 1 1 1 1 WH1 domain Macoilin PF09726.9 KFO99472.1 - 1.4e-06 27.2 24.9 1.6e-06 27.0 24.9 1.0 1 0 0 1 1 1 1 Macoilin family DMPK_coil PF08826.10 KFO99472.1 - 1.3e-05 25.2 4.0 1.3e-05 25.2 4.0 3.8 2 1 1 3 3 3 1 DMPK coiled coil domain like IFT57 PF10498.9 KFO99472.1 - 7.1e-05 21.9 25.9 0.0001 21.4 25.9 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 GAS PF13851.6 KFO99472.1 - 9.5e-05 21.8 48.4 0.00042 19.7 15.4 3.5 1 1 3 4 4 4 3 Growth-arrest specific micro-tubule binding HemX PF04375.14 KFO99472.1 - 0.0008 18.8 8.2 0.0008 18.8 8.2 3.5 1 1 2 3 3 2 2 HemX, putative uroporphyrinogen-III C-methyltransferase MAD PF05557.13 KFO99472.1 - 0.0019 16.6 41.6 0.013 13.9 20.5 2.0 1 1 1 2 2 2 1 Mitotic checkpoint protein TACC_C PF05010.14 KFO99472.1 - 0.0021 17.9 26.4 0.0021 17.9 26.4 2.5 2 1 1 3 3 3 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Uso1_p115_C PF04871.13 KFO99472.1 - 0.0021 18.4 18.0 0.0021 18.4 18.0 3.3 1 1 2 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region FlaC_arch PF05377.11 KFO99472.1 - 0.003 17.9 23.1 1.8 9.0 0.4 4.9 2 2 3 5 5 5 1 Flagella accessory protein C (FlaC) BST2 PF16716.5 KFO99472.1 - 0.0034 17.9 9.4 0.0034 17.9 9.4 4.1 2 1 2 4 4 3 1 Bone marrow stromal antigen 2 DUF4201 PF13870.6 KFO99472.1 - 0.005 16.6 6.6 0.005 16.6 6.6 3.1 2 1 1 3 3 2 2 Domain of unknown function (DUF4201) T3SSipB PF16535.5 KFO99472.1 - 0.0076 16.7 24.4 0.0077 16.7 17.8 2.8 2 1 1 3 3 3 1 Type III cell invasion protein SipB Phage_GP20 PF06810.11 KFO99472.1 - 0.011 15.6 9.5 0.011 15.6 9.5 3.7 2 1 2 4 4 3 0 Phage minor structural protein GP20 TolA_bind_tri PF16331.5 KFO99472.1 - 0.011 15.7 25.1 0.33 11.0 8.8 3.9 1 1 2 3 3 3 0 TolA binding protein trimerisation ATG16 PF08614.11 KFO99472.1 - 0.012 15.8 22.3 0.012 15.8 22.3 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 KFO99472.1 - 0.014 15.6 9.6 0.014 15.6 9.6 3.1 2 1 1 3 3 2 0 TATA element modulatory factor 1 TATA binding Laminin_II PF06009.12 KFO99472.1 - 0.016 15.2 24.2 0.14 12.2 7.0 3.0 2 1 1 3 3 3 0 Laminin Domain II Effector_1 PF04518.12 KFO99472.1 - 0.017 14.2 0.8 0.017 14.2 0.8 3.0 1 1 2 3 3 3 0 Effector from type III secretion system Sec34 PF04136.15 KFO99472.1 - 0.045 13.6 24.2 0.039 13.8 3.2 3.3 3 1 0 3 3 3 0 Sec34-like family HAP1_N PF04849.13 KFO99472.1 - 0.053 12.7 42.8 0.013 14.7 28.7 2.5 2 1 1 3 3 2 0 HAP1 N-terminal conserved region FPP PF05911.11 KFO99472.1 - 0.059 11.6 44.5 0.23 9.6 34.4 2.2 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DHR10 PF18595.1 KFO99472.1 - 0.063 13.3 51.4 0.1 12.7 9.0 4.1 2 1 2 4 4 4 0 Designed helical repeat protein 10 domain CALCOCO1 PF07888.11 KFO99472.1 - 0.069 12.0 36.8 0.054 12.3 31.1 2.4 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-H PF05837.12 KFO99472.1 - 0.074 13.5 42.9 0.12 12.8 11.1 4.1 2 1 2 4 4 4 0 Centromere protein H (CENP-H) FUSC PF04632.12 KFO99472.1 - 0.23 9.9 11.1 0.33 9.5 3.3 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF812 PF05667.11 KFO99472.1 - 0.32 9.8 41.0 0.75 8.6 23.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Lipoprotein_7 PF01540.16 KFO99472.1 - 0.47 9.7 21.5 3 7.1 10.3 2.5 1 1 1 2 2 2 0 Adhesin lipoprotein Filament PF00038.21 KFO99472.1 - 0.47 10.0 35.3 0.33 10.5 20.7 2.8 1 1 1 3 3 3 0 Intermediate filament protein VGPC1_C PF16799.5 KFO99472.1 - 0.49 10.4 21.3 0.19 11.7 5.6 3.5 2 1 1 3 3 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 MscS_porin PF12795.7 KFO99472.1 - 0.5 9.9 37.0 0.11 12.1 16.5 2.9 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF3584 PF12128.8 KFO99472.1 - 0.51 7.8 37.6 0.011 13.3 29.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF948 PF06103.11 KFO99472.1 - 0.58 10.4 8.5 2.5 8.4 0.6 2.9 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) Fez1 PF06818.15 KFO99472.1 - 0.64 10.4 41.3 0.34 11.4 9.7 3.1 1 1 2 3 3 3 0 Fez1 NPV_P10 PF05531.12 KFO99472.1 - 0.67 10.5 11.9 14 6.2 0.4 3.8 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein YabA PF06156.13 KFO99472.1 - 0.76 10.5 33.9 0.46 11.2 8.5 4.2 1 1 2 4 4 4 0 Initiation control protein YabA Mod_r PF07200.13 KFO99472.1 - 0.78 9.8 39.3 0.54 10.4 20.6 3.1 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.11 KFO99472.1 - 0.79 8.5 42.9 0.21 10.5 18.7 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein ERM PF00769.19 KFO99472.1 - 0.8 9.5 51.2 0.067 13.0 39.2 2.9 1 1 0 2 2 2 0 Ezrin/radixin/moesin family Leu_zip PF15294.6 KFO99472.1 - 1.3 8.4 36.0 0.25 10.9 29.9 2.3 1 1 1 2 2 2 0 Leucine zipper ADIP PF11559.8 KFO99472.1 - 1.5 8.9 45.8 1.2 9.2 13.5 3.9 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 KFO99472.1 - 1.6 8.0 37.0 0.12 11.6 2.9 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 KFO99472.1 - 1.6 8.8 22.5 2.8 8.0 6.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 KFO99472.1 - 1.8 8.6 48.6 0.077 13.0 6.9 4.3 2 1 2 4 4 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 KFO99472.1 - 1.9 8.6 53.1 0.066 13.3 5.8 4.0 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 KFO99472.1 - 2 7.8 40.7 0.22 10.9 20.3 2.8 1 1 1 2 2 2 0 Golgin subfamily A member 5 EzrA PF06160.12 KFO99472.1 - 2.2 6.4 35.2 0.06 11.5 27.9 2.0 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA APG6_N PF17675.1 KFO99472.1 - 2.3 8.7 51.0 0.27 11.8 18.0 3.6 1 1 2 3 3 2 0 Apg6 coiled-coil region Lebercilin PF15619.6 KFO99472.1 - 2.5 7.7 45.5 1.5 8.4 38.4 3.5 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease UPF0242 PF06785.11 KFO99472.1 - 2.5 8.1 42.8 0.062 13.4 27.4 2.8 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus BLOC1_2 PF10046.9 KFO99472.1 - 2.6 8.4 26.6 1.3 9.4 2.4 3.9 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prominin PF05478.11 KFO99472.1 - 2.7 5.8 18.5 13 3.5 18.1 2.0 1 1 0 1 1 1 0 Prominin KASH_CCD PF14662.6 KFO99472.1 - 2.7 7.8 48.7 0.45 10.3 28.2 3.1 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH Dor1 PF04124.12 KFO99472.1 - 3 6.4 24.8 0.19 10.4 18.6 1.9 2 1 1 3 3 2 0 Dor1-like family BRI3BP PF14965.6 KFO99472.1 - 3.4 7.1 12.0 2.6 7.5 1.0 3.0 2 2 2 4 4 4 0 Negative regulator of p53/TP53 AIP3 PF03915.13 KFO99472.1 - 3.5 6.6 30.3 1.6 7.8 13.4 2.1 1 1 1 2 2 2 0 Actin interacting protein 3 DUF4600 PF15372.6 KFO99472.1 - 4.7 7.7 27.7 0.14 12.6 10.7 3.4 2 1 2 4 4 3 0 Domain of unknown function (DUF4600) Seryl_tRNA_N PF02403.22 KFO99472.1 - 5.7 7.2 38.1 0.48 10.7 13.5 4.1 2 1 3 5 5 4 0 Seryl-tRNA synthetase N-terminal domain Cep57_CLD_2 PF14197.6 KFO99472.1 - 6 7.0 42.2 13 6.0 16.7 4.5 1 1 3 4 4 4 0 Centrosome localisation domain of PPC89 DUF2353 PF09789.9 KFO99472.1 - 6.1 6.1 35.9 0.42 9.9 23.5 2.6 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Exonuc_VII_L PF02601.15 KFO99472.1 - 6.4 6.3 28.8 2e+03 -2.0 28.8 2.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit YkyA PF10368.9 KFO99472.1 - 6.4 6.4 32.4 1.6 8.4 22.3 3.2 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein ING PF12998.7 KFO99472.1 - 6.9 7.3 22.4 1.2 9.8 5.8 3.3 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding AAA_13 PF13166.6 KFO99472.1 - 6.9 5.2 31.6 0.55 8.8 25.2 2.0 1 1 1 2 2 2 0 AAA domain FH2 PF02181.23 KFO99472.1 - 7.6 5.5 24.6 16 4.5 5.8 3.5 2 1 1 3 3 3 0 Formin Homology 2 Domain ApoO PF09769.9 KFO99472.1 - 7.9 6.5 8.4 7.9 6.4 0.1 3.2 3 1 0 3 3 2 0 Apolipoprotein O FOXP-CC PF16159.5 KFO99472.1 - 9 7.0 10.8 0.48 11.1 2.2 3.1 1 1 2 3 3 3 0 FOXP coiled-coil domain JMY PF15871.5 KFO99473.1 - 1.8e-116 389.3 26.2 1.8e-116 389.3 26.2 2.0 2 0 0 2 2 2 1 Junction-mediating and -regulatory protein WH2 PF02205.20 KFO99473.1 - 2.9e-05 23.7 0.5 0.00016 21.4 0.1 2.2 2 0 0 2 2 2 1 WH2 motif Robl_LC7 PF03259.17 KFO99473.1 - 0.0062 16.3 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 Roadblock/LC7 domain ZnuA PF01297.17 KFO99473.1 - 1.2 8.5 6.4 0.15 11.4 1.4 2.0 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic Jak1_Phl PF17887.1 KFO99473.1 - 5.3 7.0 21.5 0.27 11.2 7.0 3.3 3 0 0 3 3 3 0 Jak1 pleckstrin homology-like domain Amidase PF01425.21 KFO99473.1 - 7.7 5.3 8.5 1.4 7.8 1.9 2.5 2 1 0 2 2 2 0 Amidase fn3 PF00041.21 KFO99474.1 - 3.4e-16 59.3 0.1 1.8e-09 37.8 0.0 2.9 3 0 0 3 3 3 2 Fibronectin type III domain SPRY PF00622.28 KFO99474.1 - 5.4e-13 49.1 0.0 1.5e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 SPRY domain Interfer-bind PF09294.10 KFO99474.1 - 0.0001 22.5 0.1 0.11 12.8 0.0 2.7 2 0 0 2 2 2 2 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.17 KFO99474.1 - 0.0031 17.3 1.2 3.6 7.5 0.9 2.9 2 1 1 3 3 3 2 Tissue factor PRY PF13765.6 KFO99474.1 - 0.0039 16.8 0.0 0.065 12.9 0.0 2.5 2 0 0 2 2 2 1 SPRY-associated domain Pur_ac_phosph_N PF16656.5 KFO99474.1 - 0.036 14.6 0.0 0.37 11.4 0.0 2.5 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain ZYG-11_interact PF05884.12 KFO99474.1 - 0.13 11.6 0.8 0.22 10.9 0.4 1.5 1 1 0 1 1 1 0 Interactor of ZYG-11 SPX PF03105.19 KFO99474.1 - 0.29 11.0 12.8 0.52 10.2 12.8 1.4 1 1 0 1 1 1 0 SPX domain Aminopep PF10023.9 KFO99474.1 - 0.41 10.0 5.8 0.47 9.8 4.4 1.8 2 0 0 2 2 2 0 Putative aminopeptidase BLOC1_2 PF10046.9 KFO99474.1 - 1 9.7 6.8 0.3 11.4 0.5 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Apolipoprotein PF01442.18 KFO99474.1 - 1.1 9.1 13.0 0.042 13.7 7.0 1.6 2 0 0 2 2 1 0 Apolipoprotein A1/A4/E domain DUF5082 PF16888.5 KFO99474.1 - 5.5 7.3 8.7 0.74 10.1 3.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Cep57_MT_bd PF06657.13 KFO99474.1 - 7.3 7.1 7.5 2.7 8.5 0.5 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF1664 PF07889.12 KFO99474.1 - 9.1 6.3 6.0 41 4.2 0.9 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) PDEase_I PF00233.19 KFO99475.1 - 3.2e-96 321.7 1.0 5e-96 321.0 1.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PAS PF00989.25 KFO99475.1 - 3.3e-12 46.4 0.0 9.8e-12 44.9 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KFO99475.1 - 4e-12 46.3 0.1 1.1e-11 44.9 0.1 1.8 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 KFO99475.1 - 4e-06 27.0 0.0 8.8e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KFO99475.1 - 1.7e-05 25.0 0.0 5.5e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 KFO99475.1 - 0.014 15.4 0.0 0.044 13.8 0.0 1.9 1 0 0 1 1 1 0 PAS domain HTH_Mga PF08280.11 KFO99475.1 - 0.09 12.8 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Nrap_D2 PF17403.2 KFO99475.1 - 0.13 12.0 0.3 0.43 10.4 0.3 1.7 1 1 0 1 1 1 0 Nrap protein PAP/OAS-like domain Amidinotransf PF02274.17 KFO99476.1 - 1.7e-09 37.2 0.0 1.5e-05 24.3 0.0 3.5 3 1 0 3 3 3 3 Amidinotransferase AMP-binding PF00501.28 KFO99477.1 - 2.1e-44 151.8 0.0 2.4e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFO99477.1 - 3.7e-05 24.6 0.0 0.00011 23.2 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pyridoxal_deC PF00282.19 KFO99478.1 - 1.5e-166 553.8 0.0 1.8e-166 553.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KFO99478.1 - 0.00065 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KFO99478.1 - 0.031 13.4 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Ank_2 PF12796.7 KFO99479.1 - 2.9e-37 127.1 5.3 1.8e-15 57.3 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFO99479.1 - 2.4e-25 88.2 0.3 1.4e-09 38.0 0.1 4.9 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KFO99479.1 - 2.7e-24 84.5 0.6 9.1e-09 35.4 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KFO99479.1 - 1e-22 80.1 0.3 6.6e-10 39.3 0.1 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFO99479.1 - 1.7e-21 74.0 0.1 2.9e-06 27.2 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat AAA_23 PF13476.6 KFO99479.1 - 0.042 14.4 1.5 0.059 13.9 1.5 1.3 1 0 0 1 1 1 0 AAA domain LAMTOR5 PF16672.5 KFO99479.1 - 0.043 13.7 0.4 0.12 12.3 0.2 1.9 1 1 0 1 1 1 0 Ragulator complex protein LAMTOR5 DUF4265 PF14085.6 KFO99479.1 - 0.34 10.9 6.4 5.3 7.1 0.1 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4265) GrpE PF01025.19 KFO99479.1 - 1.1 8.9 10.1 3.2 7.4 10.1 1.8 1 0 0 1 1 1 0 GrpE TPD52 PF04201.15 KFO99479.1 - 1.4 8.6 6.4 2.7 7.6 6.4 1.4 1 0 0 1 1 1 0 Tumour protein D52 family UCH PF00443.29 KFO99480.1 - 1e-80 271.0 5.4 1e-80 271.0 5.4 2.4 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.11 KFO99480.1 - 4.7e-30 104.1 5.3 4.7e-30 104.1 5.3 2.7 2 1 0 2 2 2 1 USP8 dimerisation domain UCH_1 PF13423.6 KFO99480.1 - 1e-20 74.6 4.3 1e-20 74.6 4.3 2.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 KFO99480.1 - 5.4e-06 26.9 0.0 2.8e-05 24.6 0.0 2.4 1 0 0 1 1 1 1 Rhodanese-like domain WW PF00397.26 KFO99480.1 - 0.078 13.1 0.2 0.21 11.7 0.2 1.8 1 0 0 1 1 1 0 WW domain Metallothio_Pro PF02069.16 KFO99480.1 - 0.19 12.0 1.0 0.59 10.4 0.7 1.9 2 0 0 2 2 2 0 Prokaryotic metallothionein UCH PF00443.29 KFO99481.1 - 3.5e-43 147.9 0.0 4.3e-43 147.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFO99481.1 - 3.8e-17 62.9 0.8 5e-17 62.5 0.8 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Jas PF16135.5 KFO99481.1 - 2 8.7 6.2 1.1 9.5 1.6 2.3 2 0 0 2 2 2 0 TPL-binding domain in jasmonate signalling LSDAT_euk PF18139.1 KFO99482.1 - 3.1e-118 394.0 0.0 4.5e-118 393.5 0.0 1.2 1 0 0 1 1 1 1 SLOG in TRPM TRPM_tetra PF16519.5 KFO99482.1 - 5.3e-27 93.7 1.2 1.1e-26 92.6 1.2 1.6 1 0 0 1 1 1 1 Tetramerisation domain of TRPM LSDAT_prok PF18171.1 KFO99482.1 - 7.5e-20 71.0 0.6 1.5e-19 70.0 0.6 1.5 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 KFO99482.1 - 1.3e-09 37.7 21.4 2.2e-09 36.9 21.4 1.4 1 0 0 1 1 1 1 Ion transport protein DUF1820 PF08850.11 KFO99482.1 - 0.22 12.1 1.4 0.85 10.2 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1820) Peptidase_A22B PF04258.13 KFO99483.1 - 2.6e-81 273.3 18.3 4e-81 272.7 18.3 1.2 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.22 KFO99483.1 - 4e-05 23.5 0.0 7.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 PA domain PKD_channel PF08016.12 KFO99483.1 - 0.0077 15.0 11.4 0.014 14.1 11.4 1.4 1 0 0 1 1 1 1 Polycystin cation channel Presenilin PF01080.17 KFO99483.1 - 0.01 14.6 27.3 0.011 14.5 4.3 2.1 2 0 0 2 2 2 0 Presenilin Pox_EPC_I2-L1 PF12575.8 KFO99483.1 - 0.091 13.0 0.2 0.091 13.0 0.2 3.4 3 1 1 4 4 4 0 Poxvirus entry protein complex L1 and I2 MMPL PF03176.15 KFO99483.1 - 2 7.3 4.2 3.9 6.3 0.1 2.3 2 0 0 2 2 2 0 MMPL family Tmemb_9 PF05434.11 KFO99483.1 - 4.1 7.3 5.4 23 4.9 0.0 2.7 2 0 0 2 2 2 0 TMEM9 PBD PF00786.28 KFO99484.1 - 2.6e-05 24.5 0.2 3.6e-05 24.0 0.2 1.3 1 0 0 1 1 1 1 P21-Rho-binding domain AAA_18 PF13238.6 KFO99485.1 - 0.0012 19.4 0.0 0.002 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Pyr_redox_2 PF07992.14 KFO99486.1 - 4.3e-17 62.3 0.1 1.1e-11 44.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Snapin_Pallidin PF14712.6 KFO99487.1 - 4.4e-22 78.3 2.9 5.6e-22 78.0 2.9 1.1 1 0 0 1 1 1 1 Snapin/Pallidin DUF2353 PF09789.9 KFO99487.1 - 0.00011 21.7 2.9 0.00019 20.9 0.4 1.8 1 1 1 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) Rad33 PF08730.10 KFO99487.1 - 0.013 15.5 0.1 0.015 15.3 0.1 1.1 1 0 0 1 1 1 0 Rad33 PIN_4 PF13638.6 KFO99487.1 - 0.013 15.7 0.4 0.015 15.5 0.4 1.1 1 0 0 1 1 1 0 PIN domain Cation_efflux PF01545.21 KFO99488.1 - 2.7e-51 174.2 17.8 3.3e-51 173.9 17.8 1.1 1 0 0 1 1 1 1 Cation efflux family Polysacc_synt_C PF14667.6 KFO99488.1 - 0.0022 18.0 1.2 0.0022 18.0 1.2 2.2 3 0 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain PHO4 PF01384.20 KFO99488.1 - 0.0031 16.6 3.3 0.0042 16.2 3.3 1.3 1 0 0 1 1 1 1 Phosphate transporter family CitMHS PF03600.16 KFO99488.1 - 0.13 11.4 3.9 0.048 12.9 0.3 1.9 2 0 0 2 2 2 0 Citrate transporter DUF1282 PF06930.12 KFO99488.1 - 0.16 11.8 11.3 1.6 8.5 7.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1282) B12D PF06522.11 KFO99489.1 - 6.2e-23 80.4 0.0 7e-23 80.2 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DTW PF03942.15 KFO99490.1 - 7.5e-47 159.6 0.0 1.2e-46 159.0 0.0 1.3 1 0 0 1 1 1 1 DTW domain FGF PF00167.18 KFO99491.1 - 7e-49 165.1 1.9 9e-49 164.7 1.9 1.1 1 0 0 1 1 1 1 Fibroblast growth factor GalKase_gal_bdg PF10509.9 KFO99492.1 - 5.5e-25 86.7 0.0 1.1e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KFO99492.1 - 2e-14 53.5 0.3 5e-14 52.3 0.3 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KFO99492.1 - 1.4e-13 51.0 0.0 6.3e-13 48.9 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases C terminal PCI PF01399.27 KFO99493.1 - 6.7e-26 90.8 1.8 6.7e-26 90.8 1.8 2.6 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.17 KFO99493.1 - 0.086 13.0 1.5 21 5.5 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFO99493.1 - 0.16 11.8 2.0 17 5.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat FliS PF02561.14 KFO99493.1 - 0.23 11.8 5.6 0.32 11.3 3.4 2.5 2 0 0 2 2 2 0 Flagellar protein FliS TPR_7 PF13176.6 KFO99493.1 - 0.47 10.6 4.3 74 3.7 0.0 5.2 7 0 0 7 7 7 0 Tetratricopeptide repeat PID PF00640.23 KFO99494.1 - 3.1e-46 156.9 0.1 5.3e-46 156.1 0.1 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.24 KFO99494.1 - 2.5e-16 59.5 0.0 9.4e-16 57.7 0.0 2.0 2 0 0 2 2 2 1 SH2 domain EGF_CA PF07645.15 KFO99495.1 - 0 1068.6 718.6 1.9e-11 44.0 6.8 48.6 48 1 1 49 49 49 44 Calcium-binding EGF domain cEGF PF12662.7 KFO99495.1 - 8.3e-216 697.0 424.9 5.2e-10 39.1 0.8 50.6 49 0 0 49 49 49 42 Complement Clr-like EGF-like TB PF00683.17 KFO99495.1 - 7.7e-118 384.1 148.7 2.9e-15 55.7 9.5 11.1 9 0 0 9 9 9 9 TB domain EGF PF00008.27 KFO99495.1 - 5.7e-112 365.4 698.0 0.00026 21.2 7.8 50.3 49 0 0 49 49 49 45 EGF-like domain hEGF PF12661.7 KFO99495.1 - 2.2e-103 335.8 659.4 0.00011 22.7 4.4 52.3 50 0 0 50 50 50 42 Human growth factor-like EGF FXa_inhibition PF14670.6 KFO99495.1 - 5e-103 337.1 724.8 4.2e-10 39.7 8.9 50.0 43 6 7 50 50 50 43 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 KFO99495.1 - 2e-58 194.3 626.7 1.6e-10 41.0 11.6 49.9 49 1 1 50 50 50 41 EGF domain Fibrillin_U_N PF18193.1 KFO99495.1 - 4.8e-16 58.6 7.4 4.8e-16 58.6 7.4 10.2 10 0 0 10 10 10 1 Fibrillin 1 unique N-terminal domain Plasmod_Pvs28 PF06247.11 KFO99495.1 - 6.7e-10 39.1 523.9 0.004 17.4 3.7 45.8 42 3 3 45 45 45 27 Pvs28 EGF domain dUTPase PF00692.19 KFO99496.1 - 1.6e-25 89.2 0.0 1.7e-25 89.2 0.0 1.0 1 0 0 1 1 1 1 dUTPase AA_permease PF00324.21 KFO99497.1 - 7.6e-151 503.0 38.1 9.2e-151 502.7 38.1 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KFO99497.1 - 1.1e-149 499.2 2.9 1.1e-148 495.8 2.9 2.1 1 1 0 1 1 1 1 Solute carrier family 12 AA_permease_N PF08403.10 KFO99497.1 - 2e-32 110.5 0.0 1.4e-30 104.6 0.1 2.7 3 0 0 3 3 3 1 Amino acid permease N-terminal AA_permease_2 PF13520.6 KFO99497.1 - 1.3e-21 76.9 42.4 2.1e-21 76.3 42.4 1.2 1 0 0 1 1 1 1 Amino acid permease Cortexin PF11057.8 KFO99498.1 - 8.7e-35 118.4 0.1 9.4e-35 118.3 0.1 1.0 1 0 0 1 1 1 1 Cortexin of kidney RRM_1 PF00076.22 KFO99499.1 - 3.8e-56 186.8 0.6 5.7e-19 67.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFO99499.1 - 3.9e-08 33.3 0.6 0.0046 17.0 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.8 KFO99499.1 - 4e-06 26.8 0.1 0.012 15.7 0.0 2.8 2 0 0 2 2 2 2 Limkain b1 RRM_5 PF13893.6 KFO99499.1 - 7.4e-05 22.3 0.0 0.058 13.0 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFO99499.1 - 0.002 18.0 0.0 0.51 10.2 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 KFO99499.1 - 0.004 17.0 0.0 16 5.3 0.0 3.7 3 1 1 4 4 4 1 Rrp7 RRM-like N-terminal domain DUF3932 PF13068.6 KFO99499.1 - 0.0071 16.6 0.0 1.5 9.1 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3932) DbpA PF03880.15 KFO99499.1 - 0.075 13.0 0.0 10 6.2 0.0 2.6 2 0 0 2 2 2 0 DbpA RNA binding domain Na_Ca_ex PF01699.24 KFO99500.1 - 2.2e-49 167.3 41.9 2.8e-27 95.5 17.3 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF2456 PF10445.9 KFO99500.1 - 0.66 10.1 7.3 0.53 10.4 1.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2456) SPC25 PF06703.11 KFO99500.1 - 1 9.1 4.8 0.28 10.9 0.6 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF998 PF06197.13 KFO99500.1 - 8.3 6.0 18.6 0.42 10.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF998) Sema PF01403.19 KFO99501.1 - 5.7e-120 401.0 0.0 1.1e-119 400.1 0.0 1.3 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 KFO99501.1 - 1e-05 26.0 3.1 2.5e-05 24.7 3.1 1.7 1 0 0 1 1 1 1 Plexin repeat Rav1p_C PF12234.8 KFO99502.1 - 2.9e-82 277.1 0.2 1.8e-72 244.7 0.2 2.4 2 0 0 2 2 2 2 RAVE protein 1 C terminal WD40 PF00400.32 KFO99502.1 - 2e-15 56.9 26.4 0.021 15.7 0.0 12.0 13 0 0 13 13 13 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO99502.1 - 3.6e-06 27.2 0.2 0.046 14.0 0.0 4.6 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain OLF PF02191.16 KFO99503.1 - 1.4e-63 214.8 0.5 1.6e-63 214.6 0.5 1.0 1 0 0 1 1 1 1 Olfactomedin-like domain Collagen PF01391.18 KFO99503.1 - 1.4e-16 60.0 64.8 7e-10 38.5 27.8 2.9 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) p450 PF00067.22 KFO99504.1 - 3e-105 352.7 0.2 3.5e-105 352.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF758 PF05527.11 KFO99505.1 - 3e-80 268.5 8.3 3.4e-80 268.3 8.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) Seadorna_VP6 PF07407.11 KFO99505.1 - 0.02 13.9 1.5 0.025 13.5 0.6 1.4 1 1 0 1 1 1 0 Seadornavirus VP6 protein RPAP3_C PF13877.6 KFO99505.1 - 0.022 15.3 1.9 0.038 14.5 0.7 1.9 2 1 0 2 2 2 0 Potential Monad-binding region of RPAP3 Rsd_AlgQ PF04353.13 KFO99505.1 - 0.027 14.4 4.0 0.89 9.5 2.4 2.2 1 1 1 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ CdvA PF18822.1 KFO99505.1 - 0.046 13.6 1.5 0.046 13.6 1.5 2.0 1 1 1 2 2 2 0 CdvA-like coiled-coil domain DUF2408 PF10303.9 KFO99505.1 - 0.078 13.5 1.9 0.34 11.5 1.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DALR_1 PF05746.15 KFO99505.1 - 0.14 12.3 2.3 0.21 11.8 1.6 1.6 1 1 0 1 1 1 0 DALR anticodon binding domain SGIII PF15467.6 KFO99506.1 - 6.8e-219 727.7 33.2 7.6e-219 727.5 33.2 1.0 1 0 0 1 1 1 1 Secretogranin-3 DUF2680 PF10925.8 KFO99506.1 - 2.2e-05 24.4 11.9 0.084 12.9 0.2 4.6 5 0 0 5 5 5 3 Protein of unknown function (DUF2680) ParE_toxin PF05016.15 KFO99506.1 - 0.21 12.2 3.2 0.77 10.4 0.3 3.1 2 2 1 3 3 3 0 ParE toxin of type II toxin-antitoxin system, parDE CNDH2_C PF16858.5 KFO99506.1 - 3.4 7.5 29.6 0.73 9.6 9.0 2.8 1 1 1 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Hormone_2 PF00123.20 KFO99507.1 - 1.8 8.5 0.0 1.8 8.5 0.0 2.4 3 0 0 3 3 3 0 Peptide hormone Tropomodulin PF03250.14 KFO99508.1 - 6.3e-59 198.1 5.3 1.5e-58 196.8 5.3 1.6 1 0 0 1 1 1 1 Tropomodulin LRR_6 PF13516.6 KFO99508.1 - 0.0015 18.4 1.6 0.0076 16.2 0.1 2.9 2 0 0 2 2 2 1 Leucine Rich repeat PARP_reg PF02877.14 KFO99508.1 - 0.059 13.5 0.3 14 5.8 0.1 2.6 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain HDC PF02329.16 KFO99508.1 - 0.067 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Histidine carboxylase PI chain Ribosomal_S13 PF00416.22 KFO99508.1 - 0.14 12.5 0.8 0.97 9.8 0.1 2.5 3 0 0 3 3 3 0 Ribosomal protein S13/S18 LRR_4 PF12799.7 KFO99508.1 - 0.84 10.2 6.1 2.4 8.7 0.4 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Leo1 PF04004.13 KFO99509.1 - 4.5e-54 182.7 0.0 4.5e-54 182.7 0.0 3.2 2 1 0 2 2 2 1 Leo1-like protein Pkinase PF00069.25 KFO99510.1 - 7.5e-71 238.6 0.0 1.1e-70 238.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO99510.1 - 7.2e-26 91.0 0.0 1.7e-25 89.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFO99510.1 - 0.0065 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DIL PF01843.19 KFO99512.1 - 2.1e-28 98.6 1.3 2.1e-28 98.6 1.3 3.5 3 0 0 3 3 3 1 DIL domain IQ PF00612.27 KFO99512.1 - 0.00039 20.0 2.4 0.0015 18.1 2.4 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif Csm1_N PF18504.1 KFO99512.1 - 0.0098 16.2 2.2 0.0098 16.2 2.2 9.6 5 2 2 8 8 8 1 Csm1 N-terminal domain Pilus_CpaD PF09476.10 KFO99512.1 - 0.44 10.2 3.4 0.36 10.5 0.8 2.1 1 1 1 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) DUF4407 PF14362.6 KFO99512.1 - 0.94 8.8 55.4 13 5.1 28.3 4.3 1 1 1 3 3 3 0 Domain of unknown function (DUF4407) Myosin_head PF00063.21 KFO99513.1 - 7.1e-269 893.7 16.9 8.5e-269 893.4 16.9 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 KFO99513.1 - 1.9e-17 61.4 26.6 9.6e-06 25.0 1.4 4.8 4 0 0 4 4 4 4 IQ calmodulin-binding motif Myosin_N PF02736.19 KFO99513.1 - 0.00024 20.9 0.0 0.00056 19.7 0.0 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 KFO99513.1 - 0.0091 16.3 0.0 0.026 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFO99513.1 - 0.019 15.3 0.0 0.068 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 KFO99513.1 - 0.083 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 KFO99513.1 - 0.085 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain PRK PF00485.18 KFO99513.1 - 0.088 12.5 0.3 0.35 10.6 0.4 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Myosin_head PF00063.21 KFO99514.1 - 1.7e-287 955.2 3.9 2e-287 954.9 3.9 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 KFO99514.1 - 3.9e-17 60.4 33.5 3.9e-05 23.1 3.5 4.7 4 0 0 4 4 4 4 IQ calmodulin-binding motif AAA_22 PF13401.6 KFO99514.1 - 0.012 15.9 0.0 0.035 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Myosin_N PF02736.19 KFO99514.1 - 0.012 15.4 0.5 0.027 14.3 0.2 1.8 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 KFO99514.1 - 0.019 15.4 0.0 0.053 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 KFO99514.1 - 0.14 11.2 0.0 0.29 10.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Endosulfine PF04667.17 KFO99515.1 - 6.9e-11 42.1 1.0 9.2e-11 41.7 1.0 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Ntox30 PF15532.6 KFO99515.1 - 0.058 13.8 0.0 0.071 13.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin 30 Chromosome_seg PF13889.6 KFO99516.1 - 2.1e-19 69.4 0.3 5.3e-19 68.1 0.3 1.8 1 0 0 1 1 1 1 Chromosome segregation during meiosis DUF4210 PF13915.6 KFO99516.1 - 1.6e-13 51.1 0.1 4.9e-13 49.5 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Catalase-rel PF06628.12 KFO99516.1 - 0.11 12.7 0.3 31 4.9 0.1 3.1 3 0 0 3 3 3 0 Catalase-related immune-responsive CUT PF02376.15 KFO99517.1 - 7.9e-32 109.3 0.7 1.2e-31 108.7 0.7 1.3 1 0 0 1 1 1 1 CUT domain Homeodomain PF00046.29 KFO99517.1 - 2.4e-10 40.1 0.7 4.8e-10 39.1 0.7 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFO99517.1 - 0.00066 19.5 0.0 0.0018 18.2 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain RVT_1 PF00078.27 KFO99518.1 - 0.08 12.4 0.0 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) C2 PF00168.30 KFO99519.1 - 1.3e-06 28.7 0.0 1.6e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.9 KFO99520.1 - 8.4e-48 162.3 2.3 5.5e-47 159.7 2.3 2.6 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KFO99520.1 - 1.9e-45 153.4 4.4 3.6e-27 94.7 0.3 3.5 3 0 0 3 3 3 2 C2 domain DUF1041 PF06292.17 KFO99520.1 - 4.5e-35 120.2 0.2 4.5e-35 120.2 0.2 3.5 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1041) C1_1 PF00130.22 KFO99520.1 - 5.1e-11 42.3 6.2 1.1e-10 41.2 6.2 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FlaC_arch PF05377.11 KFO99520.1 - 0.042 14.2 2.9 0.47 10.9 2.9 2.9 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) zf-RING-like PF08746.11 KFO99520.1 - 0.75 10.1 4.5 2.3 8.6 4.5 1.9 1 0 0 1 1 1 0 RING-like domain IBR PF01485.21 KFO99521.1 - 3.9e-19 68.6 42.1 2.1e-14 53.5 10.1 3.1 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain Med14 PF08638.11 KFO99521.1 - 0.0086 15.5 1.5 0.016 14.6 0.4 2.0 2 0 0 2 2 2 1 Mediator complex subunit MED14 OmpH PF03938.14 KFO99521.1 - 0.06 13.7 0.5 0.06 13.7 0.5 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Guanylate_kin PF00625.21 KFO99522.1 - 3.5e-41 140.9 0.0 3.9e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase RsgA_GTPase PF03193.16 KFO99522.1 - 0.028 14.3 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase PAP2 PF01569.21 KFO99524.1 - 2.2e-28 98.7 1.3 2.2e-28 98.7 1.3 1.5 2 0 0 2 2 2 1 PAP2 superfamily Bax1-I PF01027.20 KFO99524.1 - 0.085 12.7 1.2 2.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 PAP2_3 PF14378.6 KFO99524.1 - 0.56 9.9 6.1 20 4.8 6.1 2.6 1 1 0 1 1 1 0 PAP2 superfamily zf-H2C2_2 PF13465.6 KFO99525.1 - 2.2e-12 46.8 17.2 1.9e-05 24.9 3.4 3.2 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFO99525.1 - 3e-10 40.0 17.1 0.00016 22.2 1.4 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFO99525.1 - 1.1e-09 38.2 18.7 0.00041 20.6 2.4 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFO99525.1 - 1.8e-06 28.1 9.6 0.019 15.2 0.4 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFO99525.1 - 1.7e-05 25.1 11.4 0.042 14.3 0.6 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFO99525.1 - 0.00078 19.7 1.2 0.00078 19.7 1.2 2.2 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding Prok-RING_1 PF14446.6 KFO99525.1 - 0.0026 17.6 5.7 1.1 9.2 0.2 3.2 3 0 0 3 3 3 2 Prokaryotic RING finger family 1 XPA_N PF01286.18 KFO99525.1 - 0.0037 17.3 2.3 0.75 9.9 0.0 3.1 3 0 0 3 3 3 1 XPA protein N-terminal Zn-ribbon_8 PF09723.10 KFO99525.1 - 0.0059 16.7 6.1 0.033 14.3 1.5 2.4 2 1 0 2 2 2 1 Zinc ribbon domain zf-C2H2_6 PF13912.6 KFO99525.1 - 0.0059 16.6 16.5 0.081 13.0 1.9 3.4 3 1 0 3 3 3 1 C2H2-type zinc finger zf-AN1 PF01428.16 KFO99525.1 - 0.0088 16.2 5.4 1 9.6 0.1 3.2 3 0 0 3 3 3 1 AN1-like Zinc finger zf-C2H2_9 PF16293.5 KFO99525.1 - 0.01 15.6 1.2 0.48 10.3 0.1 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) UBZ_FAAP20 PF15750.5 KFO99525.1 - 0.01 15.7 2.7 2.4 8.2 0.2 2.9 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger FYVE PF01363.21 KFO99525.1 - 0.023 14.8 7.0 0.59 10.3 1.2 2.4 1 1 1 2 2 2 0 FYVE zinc finger zf-C2H2_2 PF12756.7 KFO99525.1 - 0.032 14.6 9.9 0.56 10.6 0.5 2.6 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Zn-C2H2_12 PF18112.1 KFO99525.1 - 0.038 14.5 7.8 2.5 8.6 3.1 3.5 3 1 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zinc-ribbons_6 PF07191.12 KFO99525.1 - 0.043 13.8 4.3 0.44 10.6 0.7 2.4 1 1 1 2 2 2 0 zinc-ribbons zf-CHCC PF10276.9 KFO99525.1 - 0.052 13.6 4.2 18 5.5 0.5 3.1 3 0 0 3 3 3 0 Zinc-finger domain Cript PF10235.9 KFO99525.1 - 0.052 14.1 7.3 0.13 12.9 0.2 2.4 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT C1_2 PF03107.16 KFO99525.1 - 0.054 13.8 9.4 4.2 7.8 1.9 3.1 2 1 1 3 3 3 0 C1 domain zf-HIT PF04438.16 KFO99525.1 - 0.054 13.4 5.9 8.1 6.4 0.2 3.1 3 0 0 3 3 3 0 HIT zinc finger zf-RING_5 PF14634.6 KFO99525.1 - 0.054 13.5 5.6 1.6 8.7 3.1 2.8 2 1 1 3 3 3 0 zinc-RING finger domain PHD_4 PF16866.5 KFO99525.1 - 0.069 13.3 3.3 0.12 12.5 1.2 2.0 1 1 1 2 2 2 0 PHD-finger zf-C2HC_2 PF13913.6 KFO99525.1 - 0.07 13.0 0.5 0.07 13.0 0.5 3.0 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-RVT PF13966.6 KFO99525.1 - 0.079 13.7 3.0 18 6.1 0.0 2.9 1 1 2 3 3 3 0 zinc-binding in reverse transcriptase DUF2256 PF10013.9 KFO99525.1 - 0.11 12.7 5.7 14 5.9 0.3 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn_ribbon_SprT PF17283.2 KFO99525.1 - 0.11 12.4 5.6 11 6.0 0.3 3.2 3 0 0 3 3 3 0 SprT-like zinc ribbon domain Vps39_2 PF10367.9 KFO99525.1 - 0.11 12.9 2.3 5.2 7.6 0.1 2.6 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 DZR PF12773.7 KFO99525.1 - 0.12 12.4 6.6 1.3 9.2 6.6 2.0 1 1 0 1 1 1 0 Double zinc ribbon BolA PF01722.18 KFO99525.1 - 0.12 12.7 0.1 0.19 12.0 0.1 1.5 1 1 0 1 1 1 0 BolA-like protein C1_4 PF07975.12 KFO99525.1 - 0.14 12.5 4.0 1.2 9.4 1.7 2.5 2 1 1 3 3 3 0 TFIIH C1-like domain YyzF PF14116.6 KFO99525.1 - 0.18 11.9 3.7 18 5.5 0.2 2.9 3 0 0 3 3 3 0 YyzF-like protein DUF2225 PF09986.9 KFO99525.1 - 0.19 11.4 2.6 0.41 10.3 0.1 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) zf_UBZ PF18439.1 KFO99525.1 - 0.19 11.3 9.9 1.8 8.2 0.1 3.5 3 1 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Rtf2 PF04641.12 KFO99525.1 - 0.24 10.7 4.4 0.3 10.4 0.4 2.2 1 1 1 2 2 2 0 Rtf2 RING-finger zf-FCS PF06467.14 KFO99525.1 - 0.27 11.2 6.3 10 6.1 2.5 2.9 2 1 1 3 3 3 0 MYM-type Zinc finger with FCS sequence motif TFIIS_C PF01096.18 KFO99525.1 - 0.27 11.1 5.2 3.1 7.7 1.0 3.0 2 1 1 3 3 3 0 Transcription factor S-II (TFIIS) Elf1 PF05129.13 KFO99525.1 - 0.35 10.9 9.0 0.71 10.0 2.1 2.8 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Endonuclease_7 PF02945.15 KFO99525.1 - 0.39 10.7 6.9 0.14 12.1 1.7 1.9 1 1 1 2 2 2 0 Recombination endonuclease VII zinc_ribbon_9 PF14369.6 KFO99525.1 - 0.5 10.7 4.6 7.2 7.0 0.4 2.9 3 0 0 3 3 3 0 zinc-ribbon Prok-RING_4 PF14447.6 KFO99525.1 - 0.5 10.3 5.8 0.37 10.7 0.6 2.7 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 HNH PF01844.23 KFO99525.1 - 0.52 10.5 10.7 1.6 8.9 0.3 3.1 3 0 0 3 3 3 0 HNH endonuclease Ribosomal_L34e PF01199.18 KFO99525.1 - 0.61 10.4 5.4 0.92 9.9 0.3 2.5 1 1 0 2 2 2 0 Ribosomal protein L34e Evr1_Alr PF04777.13 KFO99525.1 - 0.7 10.4 5.2 8.2 7.0 0.4 2.8 1 1 2 3 3 3 0 Erv1 / Alr family DUF2321 PF10083.9 KFO99525.1 - 1.5 8.4 5.3 1.2 8.8 1.6 1.9 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) CpXC PF14353.6 KFO99525.1 - 1.8 8.7 6.4 3 7.9 0.1 2.7 1 1 2 3 3 3 0 CpXC protein DUF3449 PF11931.8 KFO99525.1 - 6.3 6.6 9.2 6.8 6.4 0.6 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF3449) RVT_1 PF00078.27 KFO99526.1 - 0.16 11.4 0.0 0.4 10.1 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) ANAPC4_WD40 PF12894.7 KFO99527.1 - 3.5e-09 36.8 2.9 0.47 10.8 0.0 7.0 5 1 0 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 KFO99527.1 - 0.0012 18.7 1.5 0.93 9.5 0.0 3.8 4 0 0 4 4 4 2 PQQ enzyme repeat WD40 PF00400.32 KFO99527.1 - 0.0019 19.0 8.8 7.1 7.7 0.2 6.1 6 0 0 6 6 6 1 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 KFO99527.1 - 0.0093 15.3 0.0 0.05 12.9 0.0 2.2 3 0 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ_2 PF13360.6 KFO99527.1 - 0.072 12.7 0.4 1.3 8.6 0.0 3.1 3 0 0 3 3 3 0 PQQ-like domain Ser_hydrolase PF06821.13 KFO99527.1 - 0.085 12.7 0.2 0.18 11.6 0.2 1.5 1 0 0 1 1 1 0 Serine hydrolase Pkinase_Tyr PF07714.17 KFO99529.1 - 3.4e-105 351.0 0.0 4.6e-105 350.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO99529.1 - 6.2e-45 153.6 0.0 1e-44 152.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ig_3 PF13927.6 KFO99529.1 - 1.4e-33 115.4 0.0 1.8e-10 41.3 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFO99529.1 - 3.7e-33 113.5 0.0 3e-11 43.2 0.0 3.7 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KFO99529.1 - 1.9e-26 92.2 0.0 2.7e-11 43.6 0.1 3.7 3 1 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFO99529.1 - 1.2e-22 79.9 0.0 4.5e-06 26.7 0.0 4.5 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 KFO99529.1 - 7.8e-15 55.0 1.3 0.00029 21.0 0.0 5.3 4 2 1 5 5 5 3 Immunoglobulin V-set domain FGFR3_TM PF18123.1 KFO99529.1 - 1.1e-13 50.4 5.0 1.1e-13 50.4 5.0 1.9 2 0 0 2 2 2 1 Fibroblast growth factor receptor 3 transmembrane domain Ig_5 PF16681.5 KFO99529.1 - 8.6e-09 35.7 0.0 0.02 15.3 0.0 3.7 3 1 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFO99529.1 - 2.1e-05 24.0 0.0 1.9 8.1 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain Ig_4 PF16680.5 KFO99529.1 - 2.7e-05 24.3 0.0 0.33 11.2 0.0 3.3 3 0 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFO99529.1 - 0.012 15.6 0.0 7.9 6.6 0.0 3.4 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 KFO99529.1 - 0.061 13.4 0.2 5.5 7.1 0.1 3.6 3 1 1 4 4 4 0 CD80-like C2-set immunoglobulin domain Kinase-like PF14531.6 KFO99529.1 - 0.065 12.5 0.0 0.25 10.6 0.0 1.8 2 0 0 2 2 2 0 Kinase-like ATE_C PF04377.15 KFO99530.1 - 2.9e-52 176.8 0.9 1.2e-51 174.8 0.4 2.2 2 1 1 3 3 3 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KFO99530.1 - 3.8e-15 56.0 3.1 9.8e-15 54.7 3.1 1.8 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Nse4_C PF08743.10 KFO99531.1 - 1.2e-23 83.1 0.1 2.8e-23 82.0 0.0 1.7 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KFO99531.1 - 1e-14 54.3 1.4 2.3e-14 53.2 1.4 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Plant_tran PF04827.14 KFO99531.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Plant transposon protein TACC_C PF05010.14 KFO99532.1 - 4.5e-84 281.3 34.9 7.9e-84 280.5 34.9 1.4 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal PH PF00169.29 KFO99533.1 - 1.6e-32 112.1 0.2 5.6e-19 68.6 0.1 2.5 2 0 0 2 2 2 2 PH domain PH_8 PF15409.6 KFO99533.1 - 2.9e-12 46.7 0.1 2.1e-05 24.7 0.0 2.9 2 1 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 KFO99533.1 - 1.3e-08 35.2 1.7 3.5e-05 24.2 0.6 3.7 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 KFO99533.1 - 1.4e-07 31.9 0.2 0.029 14.7 0.1 2.7 2 1 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.7 KFO99533.1 - 1.5e-06 28.3 0.0 0.0024 18.0 0.0 2.4 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology PH_3 PF14593.6 KFO99533.1 - 4.5e-05 23.5 0.9 0.01 16.0 0.2 2.8 2 2 0 2 2 2 1 PH domain PH_6 PF15406.6 KFO99533.1 - 0.011 16.0 0.0 5.4 7.3 0.0 2.7 3 0 0 3 3 3 0 Pleckstrin homology domain PH_13 PF16652.5 KFO99533.1 - 0.015 15.1 0.2 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Trypsin_2 PF13365.6 KFO99534.1 - 4.4e-32 112.1 0.1 6.2e-32 111.6 0.1 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KFO99534.1 - 3.4e-16 59.7 0.0 4.9e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 KFO99534.1 - 1.6e-12 47.0 0.3 2.2e-11 43.4 0.1 2.3 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 KFO99534.1 - 9e-10 38.8 0.2 2.7e-09 37.2 0.2 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFO99534.1 - 3.6e-09 36.8 0.5 1.2e-08 35.1 0.5 2.0 1 0 0 1 1 1 1 PDZ domain Peptidase_S46 PF10459.9 KFO99534.1 - 1.1e-06 27.6 0.7 0.027 13.2 0.0 2.2 2 0 0 2 2 2 2 Peptidase S46 Peptidase_S32 PF05579.13 KFO99534.1 - 1.7e-05 24.2 0.2 0.01 15.0 0.2 2.1 1 1 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 LSM PF01423.22 KFO99534.1 - 0.0056 16.3 0.5 0.014 15.1 0.1 1.8 2 0 0 2 2 2 1 LSM domain DUF150_C PF17384.2 KFO99534.1 - 0.0082 16.3 2.6 0.41 10.8 0.3 2.7 3 0 0 3 3 3 1 RimP C-terminal SH3 domain GRASP55_65 PF04495.14 KFO99534.1 - 0.025 14.9 0.1 0.06 13.7 0.1 1.6 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Zona_pellucida PF00100.23 KFO99535.1 - 3.5e-09 36.8 0.0 3.8e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.23 KFO99536.1 - 1.1e-26 94.2 3.0 1.2e-26 94.1 3.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain SRCR PF00530.18 KFO99537.1 - 4.7e-36 123.3 3.9 5.2e-36 123.2 3.9 1.0 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFO99537.1 - 7.9e-05 23.1 0.8 7.9e-05 23.1 0.8 1.5 1 1 0 2 2 2 1 Scavenger receptor cysteine-rich domain Zona_pellucida PF00100.23 KFO99539.1 - 1e-07 32.1 0.0 1.1e-07 32.0 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.23 KFO99540.1 - 4.2e-28 98.8 4.3 4.7e-28 98.7 4.3 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain SRCR PF00530.18 KFO99541.1 - 7.9e-33 112.9 3.6 8.8e-33 112.8 3.6 1.0 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFO99541.1 - 0.032 14.8 0.1 0.032 14.8 0.1 1.5 2 0 0 2 2 2 0 Scavenger receptor cysteine-rich domain SRCR PF00530.18 KFO99542.1 - 2.1e-128 419.6 52.1 2.8e-33 114.4 8.3 4.1 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFO99542.1 - 6.1e-18 65.2 19.5 0.00033 21.1 0.2 4.9 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFO99542.1 - 1.8e-06 28.4 4.0 3.8 8.1 0.0 4.5 4 0 0 4 4 4 3 Hepsin, SRCR domain ISAV_HA PF06215.11 KFO99542.1 - 0.21 10.7 4.4 21 4.1 0.1 3.5 4 0 0 4 4 4 0 Infectious salmon anaemia virus haemagglutinin Zona_pellucida PF00100.23 KFO99543.1 - 1.2e-10 41.7 0.1 1.3e-10 41.6 0.1 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.23 KFO99544.1 - 5e-27 95.3 5.0 5.5e-27 95.2 5.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain RVT_1 PF00078.27 KFO99545.1 - 0.0086 15.6 0.0 0.016 14.8 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Apidaecin PF00807.17 KFO99545.1 - 0.19 11.9 0.3 0.45 10.7 0.0 1.7 2 0 0 2 2 2 0 Apidaecin ELL PF10390.9 KFO99546.1 - 1.2e-86 290.6 0.2 1.2e-86 290.6 0.2 2.1 2 0 0 2 2 2 1 RNA polymerase II elongation factor ELL Occludin_ELL PF07303.13 KFO99546.1 - 9e-31 106.6 6.5 9e-31 106.6 6.5 2.3 3 0 0 3 3 3 1 Occludin homology domain BTB PF00651.31 KFO99547.1 - 1.3e-25 89.8 0.6 1.7e-18 66.9 0.4 3.3 2 1 0 2 2 2 2 BTB/POZ domain Ras PF00071.22 KFO99547.1 - 6e-05 22.7 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 Ras family dUTPase_2 PF08761.11 KFO99547.1 - 0.096 12.9 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 dUTPase Rieske_2 PF13806.6 KFO99548.1 - 3e-07 30.3 0.0 1.8e-06 27.8 0.0 1.9 1 1 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 KFO99548.1 - 5.1e-05 23.1 0.1 0.00017 21.5 0.1 1.8 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain PAF PF15715.5 KFO99548.1 - 0.1 13.2 0.1 0.17 12.5 0.1 1.3 1 0 0 1 1 1 0 PCNA-associated factor histone like domain Sulfatase PF00884.23 KFO99549.1 - 9.5e-43 146.7 0.3 1.7e-42 145.9 0.3 1.4 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 KFO99549.1 - 5.4e-06 25.3 0.1 4.9e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 KFO99549.1 - 1.3e-05 25.4 0.0 4.6e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) DUF4994 PF16385.5 KFO99549.1 - 0.00018 21.4 0.2 0.0071 16.2 0.0 2.9 2 1 0 2 2 2 1 Domain of unknown function Metalloenzyme PF01676.18 KFO99549.1 - 0.0004 19.8 0.0 0.00065 19.1 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 KFO99549.1 - 0.00048 19.8 0.0 0.0016 18.1 0.0 1.8 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.12 KFO99549.1 - 0.0085 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) COX_ARM PF06481.14 KFO99549.1 - 0.22 11.5 1.2 0.26 11.2 0.2 1.7 2 0 0 2 2 2 0 COX Aromatic Rich Motif RVT_1 PF00078.27 KFO99550.1 - 0.00026 20.6 0.0 0.00043 19.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MuF_C PF18819.1 KFO99550.1 - 0.13 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Phage MuF-C-terminal domain COG5 PF10392.9 KFO99551.1 - 0.00023 21.4 15.8 0.0014 18.8 0.3 3.3 1 1 2 3 3 3 2 Golgi transport complex subunit 5 Peptidase_C16 PF01831.17 KFO99551.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase C16 family Fib_alpha PF08702.10 KFO99551.1 - 0.035 14.3 0.3 0.035 14.3 0.3 3.7 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Ssu72 PF04722.13 KFO99551.1 - 0.04 13.5 0.1 0.089 12.4 0.1 1.7 1 0 0 1 1 1 0 Ssu72-like protein DUF2894 PF11445.8 KFO99551.1 - 0.05 14.1 10.1 0.43 11.0 6.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2894) DUF1664 PF07889.12 KFO99551.1 - 0.34 11.0 18.4 14 5.7 0.6 4.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KFO99551.1 - 0.54 10.3 8.2 16 5.5 0.4 3.4 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus XhlA PF10779.9 KFO99551.1 - 1.2 9.4 12.7 5 7.4 0.0 4.5 3 1 2 5 5 5 0 Haemolysin XhlA ALMT PF11744.8 KFO99551.1 - 1.5 7.6 11.9 1.1 8.0 5.0 2.0 1 1 1 2 2 2 0 Aluminium activated malate transporter DUF1515 PF07439.11 KFO99551.1 - 2.9 8.0 5.9 0.45 10.6 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) Remorin_C PF03763.13 KFO99551.1 - 3.7 7.5 13.8 0.63 9.9 8.2 2.4 2 1 0 2 2 2 0 Remorin, C-terminal region C2 PF00168.30 KFO99553.1 - 8.2e-74 244.5 0.0 7.5e-25 87.2 0.0 3.3 3 0 0 3 3 3 3 C2 domain PRT_C PF08372.10 KFO99553.1 - 4.1e-07 29.9 7.8 4.9e-07 29.6 0.6 3.1 2 1 1 3 3 3 1 Plant phosphoribosyltransferase C-terminal DUF639 PF04842.12 KFO99553.1 - 0.00019 20.9 0.5 0.00045 19.7 0.5 1.5 1 1 0 1 1 1 1 Plant protein of unknown function (DUF639) CEP76-C2 PF15627.6 KFO99553.1 - 0.0024 17.5 0.0 0.16 11.5 0.0 2.9 3 0 0 3 3 3 1 CEP76 C2 domain Pex24p PF06398.11 KFO99553.1 - 0.0035 16.4 0.8 0.0069 15.4 0.8 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin 2OG-FeII_Oxy_4 PF13661.6 KFO99553.1 - 0.021 15.4 0.0 0.07 13.8 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily E7 PF00527.18 KFO99553.1 - 0.1 12.8 0.2 0.28 11.4 0.2 1.7 1 0 0 1 1 1 0 E7 protein, Early protein Tom22 PF04281.13 KFO99553.1 - 0.11 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF3975 PF13126.6 KFO99553.1 - 0.18 12.3 3.6 14 6.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3975) YqhR PF11085.8 KFO99553.1 - 1.4 8.9 7.0 0.35 10.8 0.8 2.5 2 0 0 2 2 2 0 Conserved membrane protein YqhR Ank_2 PF12796.7 KFO99556.1 - 1.9e-19 70.0 0.3 1.9e-15 57.2 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFO99556.1 - 3.6e-16 58.8 0.3 0.00034 20.9 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KFO99556.1 - 6e-16 56.9 0.1 0.00021 21.5 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KFO99556.1 - 2.2e-15 56.5 0.5 5.9e-06 26.5 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFO99556.1 - 3.5e-15 56.1 0.4 1.5e-09 38.2 0.0 3.3 1 1 1 3 3 3 3 Ankyrin repeats (many copies) LPD37 PF18853.1 KFO99556.1 - 0.05 13.1 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Large polyvalent protein associated domain 37 Dpy-30 PF05186.13 KFO99557.1 - 0.11 12.2 0.2 0.28 10.9 0.2 1.7 1 0 0 1 1 1 0 Dpy-30 motif Arb2 PF09757.9 KFO99558.1 - 3.2e-10 39.6 1.6 2.5e-06 26.8 1.0 2.2 1 1 1 2 2 2 2 Arb2 domain Hydrolase_4 PF12146.8 KFO99558.1 - 0.0042 16.4 0.0 0.008 15.5 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 WGG PF10273.9 KFO99558.1 - 0.13 12.9 0.0 2.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Pre-rRNA-processing protein TSR2 Arrestin_N PF00339.29 KFO99560.1 - 1.6e-36 125.6 0.1 3.1e-35 121.4 0.1 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KFO99560.1 - 3.7e-25 88.9 0.0 2.5e-21 76.5 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.15 KFO99560.1 - 0.0016 17.5 0.1 0.014 14.5 0.1 2.2 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Pet20 PF08692.10 KFO99560.1 - 0.15 12.8 0.0 0.31 11.8 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial protein Pet20 Calx-beta PF03160.14 KFO99561.1 - 9.9e-246 795.8 100.7 9.9e-15 54.5 0.3 38.7 40 1 0 40 40 40 33 Calx-beta domain Laminin_G_3 PF13385.6 KFO99561.1 - 9.4e-20 71.3 0.1 4.9e-19 69.0 0.0 2.2 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily 7tm_2 PF00002.24 KFO99561.1 - 1.6e-13 50.5 25.0 2.7e-13 49.8 25.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) EPTP PF03736.17 KFO99561.1 - 3.3e-08 33.4 14.3 0.0015 18.5 0.4 6.7 7 0 0 7 7 7 3 EPTP domain GPS PF01825.21 KFO99561.1 - 0.0098 16.4 2.7 0.026 15.1 2.7 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif PAN_4 PF14295.6 KFO99561.1 - 0.31 11.0 0.5 0.68 9.9 0.5 1.5 1 0 0 1 1 1 0 PAN domain DUF2207 PF09972.9 KFO99561.1 - 7.5 5.2 6.2 3.9 6.1 1.9 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) LysM PF01476.20 KFO99562.1 - 1.7e-05 24.8 0.1 4.6e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 LysM domain YqhR PF11085.8 KFO99562.1 - 0.02 14.8 0.2 0.028 14.4 0.2 1.2 1 0 0 1 1 1 0 Conserved membrane protein YqhR RNA_pol_3_Rpc31 PF11705.8 KFO99563.1 - 1.1e-31 110.8 24.4 1.3e-31 110.6 24.4 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 CDC27 PF09507.10 KFO99563.1 - 0.0033 16.9 15.4 0.0036 16.8 15.4 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 BUD22 PF09073.10 KFO99563.1 - 0.056 12.8 22.6 0.077 12.3 22.6 1.3 1 0 0 1 1 1 0 BUD22 PA26 PF04636.13 KFO99563.1 - 2.1 7.2 7.5 2.6 6.9 7.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Neur_chan_memb PF02932.16 KFO99563.1 - 3.7 7.6 4.7 4.4 7.3 4.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PI3K_1B_p101 PF10486.9 KFO99563.1 - 4.1 5.1 10.8 5 4.8 10.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF4820 PF16091.5 KFO99563.1 - 4.6 6.6 9.2 6.4 6.1 9.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF913 PF06025.12 KFO99563.1 - 8.4 5.3 6.7 10 5.0 6.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) EF-hand_1 PF00036.32 KFO99564.1 - 4.2e-22 76.0 14.3 1.4e-07 30.5 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFO99564.1 - 6e-22 77.9 11.6 8.1e-11 42.2 2.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFO99564.1 - 1.2e-18 65.3 10.6 5.7e-06 25.8 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KFO99564.1 - 3.1e-11 43.0 13.6 2.9e-06 27.0 0.3 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KFO99564.1 - 1.1e-10 40.5 6.5 0.024 14.1 0.3 4.6 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 KFO99564.1 - 2.4e-06 27.8 0.5 0.046 14.1 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain Caleosin PF05042.13 KFO99564.1 - 0.0009 19.2 0.5 0.42 10.5 0.0 3.2 1 1 2 3 3 3 1 Caleosin related protein HTH_40 PF14493.6 KFO99564.1 - 0.0027 18.1 1.4 0.44 11.0 0.0 2.3 1 1 1 2 2 2 2 Helix-turn-helix domain EF-hand_14 PF17959.1 KFO99564.1 - 0.0046 17.3 2.1 0.45 10.9 0.2 2.3 1 1 1 2 2 2 2 EF-hand domain UBA_2 PF08587.11 KFO99564.1 - 0.022 14.9 0.1 3.1 8.0 0.0 2.9 2 1 0 2 2 2 0 Ubiquitin associated domain (UBA) EF-hand_4 PF12763.7 KFO99564.1 - 0.068 13.1 3.9 0.071 13.1 0.3 2.4 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand MgtE_N PF03448.17 KFO99564.1 - 0.095 13.3 0.7 0.095 13.3 0.7 2.4 1 1 0 2 2 2 0 MgtE intracellular N domain DUF1296 PF06972.11 KFO99564.1 - 0.13 12.4 1.8 3.7 7.7 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1296) DUF1390 PF07150.11 KFO99564.1 - 0.22 11.2 0.5 0.37 10.5 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1390) SRF-TF PF00319.18 KFO99565.1 - 1.2e-19 69.5 0.5 2e-19 68.8 0.5 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C PF12347.8 KFO99565.1 - 1.8e-17 63.1 1.4 3.4e-17 62.2 0.1 2.2 2 0 0 2 2 2 1 Holliday junction regulator protein family C-terminal repeat Tmemb_161AB PF10268.9 KFO99566.1 - 1.3e-212 706.7 14.6 1.4e-212 706.5 14.6 1.0 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB RasGAP PF00616.19 KFO99567.1 - 2.4e-27 96.0 5.0 6.6e-19 68.4 0.1 2.7 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase SH2 PF00017.24 KFO99567.1 - 1e-23 83.2 0.1 3.4e-21 75.1 0.0 2.9 2 0 0 2 2 2 2 SH2 domain PH PF00169.29 KFO99567.1 - 3e-18 66.3 0.2 1.9e-17 63.7 0.1 2.5 2 0 0 2 2 2 1 PH domain C2 PF00168.30 KFO99567.1 - 3.4e-12 46.5 0.1 7.3e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 C2 domain SH3_1 PF00018.28 KFO99567.1 - 3.5e-10 39.3 0.0 7.6e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFO99567.1 - 5.1e-05 23.1 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 KFO99567.1 - 0.00042 20.7 1.2 0.0073 16.7 0.6 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain COX7C PF02935.16 KFO99568.1 - 3.6e-16 59.2 0.3 3.9e-16 59.1 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Yae1_N PF09811.9 KFO99569.1 - 7.7e-18 63.9 63.5 1.8e+04 -28.3 63.5 6.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Lipase_GDSL_2 PF13472.6 KFO99570.1 - 0.0046 17.4 0.0 0.0086 16.5 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 KFO99570.1 - 0.0081 15.4 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 OSK domain Lipase_GDSL PF00657.22 KFO99570.1 - 0.17 11.8 0.0 0.66 9.9 0.0 1.9 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase F5_F8_type_C PF00754.25 KFO99571.1 - 2.1e-61 205.7 5.7 2.7e-32 111.6 0.9 2.1 2 0 0 2 2 2 2 F5/8 type C domain EGF PF00008.27 KFO99571.1 - 4.9e-22 77.9 37.6 1.8e-08 34.5 8.5 3.6 3 0 0 3 3 3 3 EGF-like domain hEGF PF12661.7 KFO99571.1 - 2.8e-09 37.3 38.5 0.00031 21.3 4.4 4.7 4 1 0 4 4 4 3 Human growth factor-like EGF EGF_2 PF07974.13 KFO99571.1 - 9.6e-05 22.7 40.5 0.082 13.3 7.4 3.7 3 0 0 3 3 3 3 EGF-like domain Pepdidase_M14_N PF18027.1 KFO99571.1 - 1 9.7 3.2 5.3 7.4 0.2 2.7 2 1 0 2 2 2 0 Cytosolic carboxypeptidase N-terminal domain RVT_1 PF00078.27 KFO99572.1 - 0.12 11.8 0.0 0.36 10.3 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Xlink PF00193.17 KFO99573.1 - 2.2e-56 188.2 0.0 3.1e-34 117.2 0.0 2.3 2 0 0 2 2 2 2 Extracellular link domain V-set PF07686.17 KFO99573.1 - 3.4e-10 40.1 0.0 6.1e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFO99573.1 - 4.3e-05 24.0 0.0 0.00013 22.4 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFO99573.1 - 5e-05 23.3 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFO99573.1 - 0.00016 21.9 0.0 0.0026 18.1 0.0 2.3 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFO99573.1 - 0.011 15.9 0.1 0.034 14.3 0.1 1.8 1 1 0 1 1 1 0 Immunoglobulin domain Izumo-Ig PF16706.5 KFO99573.1 - 0.16 12.1 0.0 0.46 10.6 0.0 1.8 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain RVT_1 PF00078.27 KFO99574.1 - 0.00016 21.2 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.11 KFO99574.1 - 0.26 11.0 0.6 0.43 10.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) XRCC4 PF06632.12 KFO99575.1 - 2.6e-119 398.0 7.6 2.9e-119 397.9 7.6 1.0 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 ParD_antitoxin PF03693.14 KFO99575.1 - 0.0019 18.6 0.3 2.8 8.4 0.1 2.5 2 0 0 2 2 2 2 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH Leu_zip PF15294.6 KFO99575.1 - 0.0023 17.5 6.7 0.0023 17.5 6.7 1.5 2 0 0 2 2 2 1 Leucine zipper PI3K_P85_iSH2 PF16454.5 KFO99575.1 - 0.011 15.4 6.3 0.017 14.7 4.5 2.1 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain KxDL PF10241.9 KFO99575.1 - 0.52 10.6 5.6 4.6 7.6 5.1 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein Prefoldin_2 PF01920.20 KFO99575.1 - 0.66 10.0 11.2 0.16 11.9 0.7 2.8 3 0 0 3 3 3 0 Prefoldin subunit Pox_A_type_inc PF04508.12 KFO99575.1 - 5.7 7.0 7.6 11 6.0 0.6 3.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF1242 PF06842.12 KFO99576.1 - 3e-16 58.9 1.7 3.4e-16 58.7 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) WBP-1 PF11669.8 KFO99576.1 - 0.031 14.9 0.0 0.031 14.9 0.0 1.0 1 0 0 1 1 1 0 WW domain-binding protein 1 ATP-synt_S1 PF05827.12 KFO99577.1 - 5.9e-48 162.4 1.5 7.2e-48 162.1 1.5 1.1 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) SID PF11778.8 KFO99577.1 - 0.039 14.1 0.5 0.059 13.5 0.1 1.5 2 0 0 2 2 2 0 Septation initiation FAM176 PF14851.6 KFO99577.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 FAM176 family DUF3941 PF13081.6 KFO99577.1 - 0.23 11.9 0.2 0.5 10.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3941) Ribosom_S12_S23 PF00164.25 KFO99578.1 - 1.2e-52 176.3 0.9 1.5e-52 176.0 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Autophagy_act_C PF03987.15 KFO99579.1 - 7.9e-20 71.2 0.6 1.4e-19 70.4 0.6 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain SSDP PF04503.13 KFO99580.1 - 1.3e-74 252.1 75.8 2.3e-59 202.1 64.2 2.0 1 1 1 2 2 2 2 Single-stranded DNA binding protein, SSDP 4HBT PF03061.22 KFO99581.1 - 1.1e-19 70.5 0.4 3.1e-10 40.2 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily PTSIIB_sorb PF03830.15 KFO99581.1 - 0.0016 18.7 0.6 0.39 10.9 0.0 3.0 3 0 0 3 3 3 2 PTS system sorbose subfamily IIB component START PF01852.19 KFO99582.1 - 2.4e-20 72.9 0.2 2.9e-20 72.6 0.2 1.1 1 0 0 1 1 1 1 START domain Polyketide_cyc2 PF10604.9 KFO99582.1 - 0.025 14.9 0.0 0.039 14.2 0.0 1.3 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport zf-CCHC PF00098.23 KFO99583.1 - 5.6e-17 61.0 25.8 3e-06 27.1 0.6 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.6 KFO99583.1 - 4e-08 32.9 23.2 0.00042 20.1 0.5 4.2 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.6 KFO99583.1 - 0.0065 16.2 21.1 0.49 10.2 0.6 4.4 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_5 PF14787.6 KFO99583.1 - 0.037 13.7 0.3 0.037 13.7 0.3 3.7 4 0 0 4 4 4 0 GAG-polyprotein viral zinc-finger Inhibitor_I9 PF05922.16 KFO99583.1 - 0.052 14.2 0.1 0.086 13.5 0.1 1.3 1 0 0 1 1 1 0 Peptidase inhibitor I9 DUF4200 PF13863.6 KFO99583.1 - 0.12 12.8 11.7 0.2 12.1 11.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Prim_Zn_Ribbon PF08273.12 KFO99583.1 - 0.16 12.3 6.8 2.7 8.3 0.1 3.4 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase eIF3g PF12353.8 KFO99583.1 - 0.61 10.5 0.1 0.61 10.5 0.1 4.0 2 1 2 4 4 4 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_3 PF13917.6 KFO99583.1 - 9.8 6.2 14.8 8.2 6.5 0.8 4.1 2 1 2 4 4 4 0 Zinc knuckle ATP-gua_Ptrans PF00217.19 KFO99584.1 - 8.2e-82 273.8 0.0 1e-81 273.5 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 KFO99584.1 - 5.6e-31 106.7 0.0 9.6e-31 106.0 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain MutS_V PF00488.21 KFO99586.1 - 8.4e-73 244.4 0.1 2e-72 243.2 0.1 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFO99586.1 - 1.4e-35 123.3 0.8 2.7e-35 122.4 0.8 1.5 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 KFO99586.1 - 1.8e-10 41.2 0.2 7e-10 39.3 0.0 2.2 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.18 KFO99586.1 - 0.0004 20.7 0.1 0.0013 19.0 0.1 1.9 1 0 0 1 1 1 1 MutS family domain IV DHFR_1 PF00186.19 KFO99587.1 - 9.7e-27 93.6 0.0 1.1e-26 93.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrofolate reductase DUF2181 PF10223.9 KFO99588.1 - 7.1e-85 284.3 0.2 8e-85 284.1 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2181) MACPF PF01823.19 KFO99588.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 MAC/Perforin domain GAGA PF09237.11 KFO99588.1 - 0.22 11.4 0.3 0.44 10.4 0.3 1.4 1 0 0 1 1 1 0 GAGA factor DUF3480 PF11979.8 KFO99589.1 - 3.1e-93 312.5 0.0 3.5e-93 312.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3480) A1_Propeptide PF07966.12 KFO99589.1 - 0.3 11.0 1.1 12 5.9 0.0 2.6 2 0 0 2 2 2 0 A1 Propeptide DUF3480 PF11979.8 KFO99590.1 - 1.1e-27 97.0 0.4 2.3e-27 95.9 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3480) FYVE PF01363.21 KFO99590.1 - 5.3e-19 68.1 14.7 1.6e-18 66.6 14.7 1.9 1 0 0 1 1 1 1 FYVE zinc finger DUF2353 PF09789.9 KFO99591.1 - 0.0088 15.4 0.3 0.0088 15.4 0.3 4.1 1 1 1 3 3 3 1 Uncharacterized coiled-coil protein (DUF2353) AAA_18 PF13238.6 KFO99592.1 - 6.9e-28 97.8 0.0 1.5e-27 96.7 0.0 1.5 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.6 KFO99592.1 - 1.1e-06 29.1 0.3 3e-06 27.7 0.1 1.8 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 KFO99592.1 - 7.9e-05 22.9 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 KFO99592.1 - 0.00011 22.4 0.7 0.0091 16.1 0.1 2.5 2 1 0 2 2 2 1 Shikimate kinase AAA PF00004.29 KFO99592.1 - 0.00018 21.9 0.0 0.00035 21.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KFO99592.1 - 0.00085 19.5 0.1 0.0013 18.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain ADK PF00406.22 KFO99592.1 - 0.0099 16.0 0.2 0.037 14.1 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase AAA_22 PF13401.6 KFO99592.1 - 0.017 15.4 0.0 0.074 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 KFO99592.1 - 0.045 13.2 0.0 0.5 9.8 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Cytidylate_kin PF02224.18 KFO99592.1 - 0.05 13.3 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_5 PF07728.14 KFO99592.1 - 0.058 13.4 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Cytidylate_kin2 PF13189.6 KFO99592.1 - 0.059 13.5 0.0 0.09 12.9 0.0 1.5 1 1 0 1 1 1 0 Cytidylate kinase-like family RsgA_GTPase PF03193.16 KFO99592.1 - 0.06 13.2 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 KFO99592.1 - 0.097 13.1 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 KFO99592.1 - 0.1 13.0 0.2 0.14 12.5 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.12 KFO99592.1 - 0.23 11.2 0.1 0.36 10.5 0.1 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KFO99593.1 - 1.8e-61 207.3 0.0 3.8e-61 206.3 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KFO99593.1 - 5.6e-07 30.1 0.0 1.7e-06 28.6 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KFO99593.1 - 8.5e-06 25.6 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 KFO99593.1 - 9.4e-06 26.1 0.0 2.2e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KFO99593.1 - 0.00045 20.8 0.0 0.0018 18.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KFO99593.1 - 0.00072 19.1 0.0 0.0016 18.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KFO99593.1 - 0.0011 19.2 0.0 0.0028 17.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFO99593.1 - 0.0013 18.1 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_5 PF07728.14 KFO99593.1 - 0.0028 17.7 0.0 0.0063 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KFO99593.1 - 0.006 17.0 0.0 0.025 15.0 0.0 2.2 1 1 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 KFO99593.1 - 0.0082 16.4 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 KFO99593.1 - 0.0093 16.3 0.0 0.022 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_19 PF13245.6 KFO99593.1 - 0.011 16.1 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain UMP1 PF05348.11 KFO99593.1 - 0.013 15.8 0.0 0.037 14.3 0.0 1.8 1 0 0 1 1 1 0 Proteasome maturation factor UMP1 TsaE PF02367.17 KFO99593.1 - 0.031 14.3 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DMA PF03474.14 KFO99593.1 - 0.057 13.0 0.1 0.3 10.7 0.0 2.3 2 0 0 2 2 2 0 DMRTA motif AAA_14 PF13173.6 KFO99593.1 - 0.069 13.2 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KFO99593.1 - 0.095 13.1 0.1 1 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 KFO99593.1 - 0.097 12.8 0.0 0.36 10.9 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 KFO99593.1 - 0.11 12.4 0.2 0.56 10.1 0.1 2.3 2 1 0 2 2 2 0 NACHT domain Viral_helicase1 PF01443.18 KFO99593.1 - 0.13 12.0 0.1 0.36 10.5 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 KFO99593.1 - 0.16 11.7 2.2 0.26 11.0 0.1 2.1 2 1 0 2 2 2 0 AAA domain His_Phos_2 PF00328.22 KFO99594.1 - 7e-31 107.9 0.0 1.7e-30 106.6 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) zf-C3HC4_5 PF17121.5 KFO99594.1 - 0.003 17.4 1.7 0.0069 16.2 0.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Kinesin PF00225.23 KFO99595.1 - 7e-93 311.2 0.1 7e-93 311.2 0.1 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFO99595.1 - 7.5e-15 55.2 0.1 5.9e-14 52.2 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding DUF2855 PF11017.8 KFO99595.1 - 0.087 12.6 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) UPF0242 PF06785.11 KFO99595.1 - 2.7 8.0 14.1 0.92 9.6 7.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF87 PF01935.17 KFO99595.1 - 8 6.5 7.9 19 5.2 0.6 2.8 2 0 0 2 2 2 0 Helicase HerA, central domain HECT PF00632.25 KFO99596.1 - 4.8e-46 157.6 0.1 5.1e-46 157.5 0.1 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RVT_1 PF00078.27 KFO99597.1 - 0.08 12.4 0.0 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) GRAM PF02893.20 KFO99598.1 - 0.00049 19.9 0.1 0.0015 18.4 0.0 1.8 2 0 0 2 2 2 1 GRAM domain DUF5089 PF17002.5 KFO99598.1 - 0.0098 15.8 10.1 0.51 10.2 6.1 2.5 3 0 0 3 3 3 2 Domain of unknown function (DUF5089) V-SNARE_C PF12352.8 KFO99598.1 - 0.12 12.7 2.1 7.6 6.9 0.0 2.6 2 1 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus KxDL PF10241.9 KFO99598.1 - 0.38 11.1 4.3 1.1 9.6 2.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein Cupin_8 PF13621.6 KFO99599.1 - 1.3e-20 74.2 2.0 2.1e-20 73.5 2.0 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KFO99599.1 - 3.2e-20 72.7 0.2 9.5e-20 71.1 0.2 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 KFO99599.1 - 0.0073 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein TMIE PF16038.5 KFO99600.1 - 4.5e-34 116.2 0.3 5.5e-34 115.9 0.3 1.1 1 0 0 1 1 1 1 TMIE protein RCR PF12273.8 KFO99600.1 - 0.013 16.2 0.0 0.018 15.7 0.0 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Shisa PF13908.6 KFO99600.1 - 0.027 14.7 0.0 0.031 14.5 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3340 PF11818.8 KFO99600.1 - 0.042 14.0 3.6 0.14 12.4 3.7 1.6 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) LST1 PF05083.13 KFO99600.1 - 0.089 13.1 0.4 0.25 11.6 0.0 1.8 1 1 1 2 2 2 0 LST-1 protein EF-hand_6 PF13405.6 KFO99602.1 - 1.2e-08 34.1 0.1 0.012 15.5 0.0 3.7 4 1 1 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 KFO99602.1 - 7.4e-06 25.2 1.2 0.02 14.4 0.0 4.4 6 0 0 6 6 6 2 EF hand EF-hand_7 PF13499.6 KFO99602.1 - 0.00048 20.5 0.3 0.01 16.3 0.0 2.7 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KFO99602.1 - 0.0033 17.2 1.6 1.8 8.4 0.1 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 KFO99602.1 - 0.0089 16.3 0.0 0.44 10.9 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain DED PF01335.21 KFO99602.1 - 0.2 12.0 0.3 1.5 9.2 0.0 2.3 2 1 0 2 2 2 0 Death effector domain 7tm_2 PF00002.24 KFO99604.1 - 6.7e-88 294.1 13.3 8.2e-88 293.8 13.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFO99604.1 - 2.4e-19 69.4 3.0 4.5e-19 68.5 3.0 1.5 1 0 0 1 1 1 1 Hormone receptor domain Inositol_P PF00459.25 KFO99605.1 - 7.2e-35 120.8 0.5 8.6e-35 120.6 0.5 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family RuvA_N PF01330.21 KFO99605.1 - 0.02 15.0 0.1 0.043 13.9 0.1 1.5 1 0 0 1 1 1 0 RuvA N terminal domain Yae1_N PF09811.9 KFO99606.1 - 6.4e-12 45.0 42.1 0.28 10.9 2.5 4.3 2 1 0 2 2 2 2 Essential protein Yae1, N terminal FAM110_N PF14161.6 KFO99607.1 - 1.1e-44 151.0 4.0 2.7e-44 149.8 4.0 1.7 1 0 0 1 1 1 1 Centrosome-associated N terminus FAM110_C PF14160.6 KFO99607.1 - 2.3e-33 115.6 0.3 2.3e-33 115.6 0.3 2.0 2 1 0 2 2 2 1 Centrosome-associated C terminus SEP PF08059.13 KFO99608.1 - 1.3e-28 99.4 0.3 5.3e-28 97.4 0.1 2.0 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 KFO99608.1 - 1.5e-17 63.5 0.3 2.6e-17 62.8 0.3 1.3 1 0 0 1 1 1 1 UBX domain Phage_capsid PF05065.13 KFO99608.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Phage capsid family p450 PF00067.22 KFO99609.1 - 1.4e-77 261.4 0.5 1.8e-77 261.1 0.5 1.0 1 0 0 1 1 1 1 Cytochrome P450 PDZ_6 PF17820.1 KFO99611.1 - 5.4e-23 80.6 0.4 3e-14 52.6 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 KFO99611.1 - 5.4e-21 74.7 2.2 4.4e-13 49.4 0.1 2.9 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 KFO99611.1 - 2.5e-12 46.9 0.2 2.2e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 PDZ domain Beach PF02138.18 KFO99612.1 - 6.5e-115 383.3 0.0 9.8e-115 382.7 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain GRAM PF02893.20 KFO99612.1 - 2.2e-18 66.2 0.1 2.9e-17 62.6 0.1 2.7 2 0 0 2 2 2 1 GRAM domain WD40 PF00400.32 KFO99612.1 - 8.9e-15 54.8 14.1 0.037 14.9 0.0 7.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO99612.1 - 5e-06 26.7 4.6 0.12 12.7 0.1 4.9 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PH_BEACH PF14844.6 KFO99612.1 - 5.7e-06 26.4 0.0 0.5 10.5 0.0 3.8 2 1 0 2 2 2 2 PH domain associated with Beige/BEACH WD40_like PF17005.5 KFO99612.1 - 0.02 14.2 0.2 0.38 10.0 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain Hira PF07569.11 KFO99612.1 - 0.19 11.4 1.5 1.7 8.3 0.1 2.7 3 0 0 3 3 3 0 TUP1-like enhancer of split HMG_box PF00505.19 KFO99613.1 - 9e-18 64.5 0.4 2e-17 63.3 0.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFO99613.1 - 8.6e-12 45.5 0.6 1.7e-11 44.5 0.6 1.5 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.13 KFO99613.1 - 0.017 15.7 1.3 0.03 14.9 0.3 1.9 1 1 0 1 1 1 0 YABBY protein Mitofilin PF09731.9 KFO99613.1 - 0.058 12.2 5.1 0.075 11.9 5.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Carb_anhydrase PF00194.21 KFO99614.1 - 1.7e-79 267.0 0.0 1.9e-79 266.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Ras PF00071.22 KFO99616.1 - 3e-57 192.7 0.0 3.4e-57 192.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFO99616.1 - 3.9e-30 104.5 0.0 6.7e-30 103.8 0.0 1.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFO99616.1 - 5.8e-12 45.4 0.0 6.6e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFO99616.1 - 0.00072 19.2 0.0 0.00094 18.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFO99616.1 - 0.0019 17.6 0.0 0.0021 17.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KFO99616.1 - 0.0039 17.1 0.1 0.81 9.6 0.1 2.3 1 1 2 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 KFO99616.1 - 0.0064 16.6 0.0 0.0096 16.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase CRAL_TRIO PF00650.20 KFO99617.1 - 3.7e-34 117.8 0.0 5.8e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFO99617.1 - 3e-08 33.9 0.0 4.9e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFO99617.1 - 1.4e-06 28.4 0.1 2.7e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Asp_Arg_Hydrox PF05118.15 KFO99618.1 - 6.8e-56 188.4 0.3 1.2e-55 187.6 0.3 1.5 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Asp-B-Hydro_N PF05279.11 KFO99618.1 - 4e-48 164.6 0.0 4e-48 164.6 0.0 2.2 1 1 1 2 2 2 1 Aspartyl beta-hydroxylase N-terminal region TPR_6 PF13174.6 KFO99618.1 - 9.3e-08 32.2 2.8 0.012 16.2 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFO99618.1 - 3.1e-07 30.0 3.7 0.42 10.9 0.2 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFO99618.1 - 1.4e-06 28.0 2.5 0.2 12.0 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFO99618.1 - 1.9e-06 28.2 0.0 0.014 16.2 0.2 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFO99618.1 - 2.6e-06 28.0 0.2 0.0011 19.6 1.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFO99618.1 - 3e-05 24.2 0.1 0.23 11.8 0.1 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFO99618.1 - 4.8e-05 22.9 1.5 0.092 12.4 0.1 4.4 4 0 0 4 4 4 1 TPR repeat TPR_19 PF14559.6 KFO99618.1 - 6.3e-05 23.4 0.0 0.16 12.5 0.3 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFO99618.1 - 0.00018 21.2 1.5 1.2 9.1 0.0 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat YfiO PF13525.6 KFO99618.1 - 0.018 14.8 0.4 0.11 12.2 0.3 2.3 2 1 0 2 2 2 0 Outer membrane lipoprotein LUC7 PF03194.15 KFO99618.1 - 0.031 14.0 0.7 0.052 13.2 0.7 1.3 1 0 0 1 1 1 0 LUC7 N_terminus ATG27 PF09451.10 KFO99618.1 - 0.04 13.8 0.2 0.066 13.1 0.2 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 DUF2299 PF10061.9 KFO99618.1 - 0.16 11.7 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) CTNNBL PF08216.11 KFO99618.1 - 1.1 9.5 5.8 0.25 11.5 1.6 2.1 3 0 0 3 3 2 0 Catenin-beta-like, Arm-motif containing nuclear NKAIN PF05640.14 KFO99621.1 - 5.2e-69 231.6 5.5 5.7e-69 231.5 5.5 1.0 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein DUF1003 PF06210.11 KFO99621.1 - 0.014 15.5 0.2 0.021 14.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Peptidase_C26 PF07722.13 KFO99622.1 - 2.9e-25 89.3 0.0 1e-24 87.5 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 KFO99622.1 - 6.9e-09 35.7 0.0 1.1e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CRAL_TRIO PF00650.20 KFO99623.1 - 2.3e-33 115.2 0.0 3e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain DUF5007 PF16398.5 KFO99623.1 - 0.11 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5007) YTH PF04146.15 KFO99624.1 - 1.2e-39 135.9 0.5 1.2e-39 135.9 0.5 2.3 2 1 0 2 2 2 1 YT521-B-like domain TFIIA PF03153.13 KFO99624.1 - 0.012 15.6 10.3 0.02 14.9 10.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit p450 PF00067.22 KFO99625.1 - 3.7e-52 177.6 0.4 4.6e-52 177.3 0.4 1.1 1 0 0 1 1 1 1 Cytochrome P450 Arm PF00514.23 KFO99627.1 - 2.7e-05 24.0 0.0 6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat HMA PF00403.26 KFO99627.1 - 0.0017 18.7 0.1 0.0032 17.9 0.1 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Mito_fiss_reg PF05308.11 KFO99628.1 - 4.5e-80 269.3 5.7 6.2e-80 268.9 5.7 1.2 1 0 0 1 1 1 1 Mitochondrial fission regulator FlxA PF14282.6 KFO99628.1 - 0.022 14.7 2.0 0.022 14.7 2.0 1.8 2 0 0 2 2 2 0 FlxA-like protein DUF2240 PF09999.9 KFO99628.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) DnaJ PF00226.31 KFO99629.1 - 1.4e-26 92.4 2.6 2.3e-26 91.7 2.6 1.3 1 0 0 1 1 1 1 DnaJ domain Baculo_F PF12259.8 KFO99629.1 - 0.018 13.6 0.0 0.02 13.4 0.0 1.1 1 0 0 1 1 1 0 Baculovirus F protein Corona_S2 PF01601.16 KFO99629.1 - 0.026 13.0 2.3 0.031 12.8 2.3 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein CCER1 PF15482.6 KFO99629.1 - 0.66 9.8 5.5 0.89 9.4 5.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 zf-RING_UBOX PF13445.6 KFO99630.1 - 2.7e-10 40.1 4.0 8.1e-10 38.6 4.0 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFO99630.1 - 2.9e-08 33.4 2.3 2.9e-08 33.4 2.3 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFO99630.1 - 6.6e-08 32.3 3.5 6.6e-08 32.3 3.5 2.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFO99630.1 - 5.3e-07 29.9 4.5 5.3e-07 29.9 4.5 2.8 2 1 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.6 KFO99630.1 - 1.4e-06 28.2 4.6 1.4e-06 28.2 4.6 2.6 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFO99630.1 - 1.3e-05 25.0 7.2 1.3e-05 25.0 7.2 3.0 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 KFO99630.1 - 1.7e-05 24.8 9.3 1.7e-05 24.8 9.3 3.5 4 0 0 4 4 4 1 B-box zinc finger zf-RING_6 PF14835.6 KFO99630.1 - 3.1e-05 23.7 0.4 3.1e-05 23.7 0.4 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KFO99630.1 - 3.3e-05 24.0 7.1 3.3e-05 24.0 7.1 3.1 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING DUF1664 PF07889.12 KFO99630.1 - 0.018 15.1 1.7 0.052 13.6 1.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) EzrA PF06160.12 KFO99630.1 - 0.057 11.6 17.1 0.087 11.0 17.1 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TFA2_Winged_2 PF18121.1 KFO99630.1 - 0.059 13.1 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 TFA2 Winged helix domain 2 DUF1495 PF07381.11 KFO99630.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) Alveol-reg_P311 PF11092.8 KFO99630.1 - 0.21 11.8 0.7 0.68 10.1 0.7 1.8 1 0 0 1 1 1 0 Neuronal protein 3.1 (p311) zf-RING_11 PF17123.5 KFO99630.1 - 2.6 7.9 9.9 1.9 8.3 6.2 2.5 2 0 0 2 2 2 0 RING-like zinc finger GP67 PF17634.2 KFO99630.1 - 7.3 7.1 14.4 17 5.9 14.4 1.6 1 0 0 1 1 1 0 Gene product 67 CRF PF00473.17 KFO99631.1 - 1.1e-16 60.6 1.0 2.3e-16 59.6 1.0 1.6 1 0 0 1 1 1 1 Corticotropin-releasing factor family DUF3022 PF11226.8 KFO99631.1 - 0.12 12.8 0.1 0.24 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3022) Collagen PF01391.18 KFO99632.1 - 7.2e-11 41.7 22.7 7.2e-11 41.7 22.7 2.2 1 1 1 2 2 2 1 Collagen triple helix repeat (20 copies) COLFI PF01410.18 KFO99633.1 - 2.3e-56 190.7 0.0 2.5e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain SNARE PF05739.19 KFO99633.1 - 0.018 15.0 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 SNARE domain Sarcoglycan_2 PF05510.13 KFO99634.1 - 5.2e-17 61.7 0.0 2.8e-16 59.3 0.0 1.7 1 1 1 2 2 2 2 Sarcoglycan alpha/epsilon BCDHK_Adom3 PF10436.9 KFO99635.1 - 3e-26 92.2 0.0 4.4e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KFO99635.1 - 0.0036 17.8 0.0 0.0059 17.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DLL_N PF12413.8 KFO99636.1 - 2.6e-23 83.0 16.4 4.9e-23 82.2 16.4 1.5 1 0 0 1 1 1 1 Homeobox protein distal-less-like N terminal Homeodomain PF00046.29 KFO99636.1 - 3e-18 65.4 2.9 4.9e-18 64.7 2.9 1.4 1 0 0 1 1 1 1 Homeodomain RVT_1 PF00078.27 KFO99637.1 - 0.065 12.7 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) MOZ_SAS PF01853.18 KFO99638.1 - 2.7e-86 287.8 1.4 4.3e-86 287.1 1.4 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KFO99638.1 - 2.1e-23 81.6 1.6 2.1e-23 81.6 1.6 2.4 3 0 0 3 3 3 1 MYST family zinc finger domain zf-C2HC PF01530.18 KFO99638.1 - 2.7e-06 27.4 3.2 2.8e-06 27.4 1.3 1.9 2 0 0 2 2 2 1 Zinc finger, C2HC type Acetyltransf_7 PF13508.7 KFO99638.1 - 0.023 15.1 0.0 0.047 14.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-met PF12874.7 KFO99638.1 - 0.031 14.7 0.4 0.081 13.3 0.4 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type FAM117 PF15388.6 KFO99639.1 - 1.2e-117 392.9 6.4 1.4e-117 392.7 6.4 1.0 1 0 0 1 1 1 1 Protein Family FAM117 UAA PF08449.11 KFO99640.1 - 5e-52 177.0 10.3 6.8e-52 176.6 10.3 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KFO99640.1 - 6.6e-16 58.7 20.6 5.3e-08 33.1 12.4 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KFO99640.1 - 3.6e-13 49.5 7.6 4.6e-08 32.8 1.2 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family CRT-like PF08627.10 KFO99640.1 - 0.00081 18.4 7.6 0.0077 15.2 0.0 2.5 1 1 0 3 3 3 2 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 KFO99640.1 - 0.029 13.5 2.4 0.54 9.4 2.5 2.3 1 1 0 1 1 1 0 Nucleotide-sugar transporter BTB PF00651.31 KFO99641.1 - 1.7e-26 92.7 0.0 2.5e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain MATH PF00917.26 KFO99641.1 - 3.2e-07 30.5 0.1 5.6e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 MATH domain OATP PF03137.20 KFO99642.1 - 5e-181 602.7 11.0 3.6e-179 596.6 11.0 2.0 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFO99642.1 - 2.5e-19 69.4 32.9 7.8e-14 51.4 15.7 3.0 3 0 0 3 3 3 3 Major Facilitator Superfamily zf-Di19 PF05605.12 KFO99644.1 - 0.028 14.7 1.3 0.46 10.8 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-UDP PF14569.6 KFO99644.1 - 0.042 14.0 0.4 1.3 9.2 0.1 2.2 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-ribbon_3 PF13248.6 KFO99644.1 - 0.059 12.8 1.1 4.2 6.9 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Cys_rich_CPXG PF14255.6 KFO99644.1 - 0.098 12.6 1.4 4.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Cysteine-rich CPXCG DZR PF12773.7 KFO99644.1 - 0.13 12.3 1.2 1 9.5 1.1 2.1 1 1 0 1 1 1 0 Double zinc ribbon Cadherin PF00028.17 KFO99646.1 - 1.1e-14 54.6 0.0 3.5e-13 49.8 0.0 2.0 2 0 0 2 2 2 2 Cadherin domain MAM PF00629.23 KFO99649.1 - 1.6e-50 171.1 0.0 3e-50 170.3 0.0 1.5 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Ig_3 PF13927.6 KFO99649.1 - 4e-49 165.1 7.9 3.1e-13 50.1 0.1 5.5 6 0 0 6 6 6 4 Immunoglobulin domain I-set PF07679.16 KFO99649.1 - 5.6e-43 144.9 0.0 1.4e-11 44.3 0.0 5.4 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_2 PF13895.6 KFO99649.1 - 6.1e-37 125.8 1.8 3.7e-08 33.6 0.0 6.0 6 0 0 6 6 6 4 Immunoglobulin domain ig PF00047.25 KFO99649.1 - 5.4e-32 109.8 0.1 2.2e-09 37.4 0.0 4.8 4 0 0 4 4 4 4 Immunoglobulin domain V-set PF07686.17 KFO99649.1 - 2.5e-13 50.2 16.7 0.0064 16.6 0.3 8.3 7 4 1 8 8 7 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFO99649.1 - 1.9e-10 40.7 0.3 0.0048 16.9 0.0 4.5 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFO99649.1 - 4.6e-05 23.4 0.1 3.2 7.9 0.0 4.3 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 KFO99649.1 - 0.00029 21.0 0.0 2.3 8.6 0.0 4.8 5 1 0 5 5 5 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFO99649.1 - 0.00098 18.6 1.1 0.94 9.1 0.0 4.2 4 0 0 4 4 4 1 Immunoglobulin domain BiPBP_C PF06832.12 KFO99649.1 - 0.029 14.4 0.0 0.091 12.8 0.0 1.9 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family C1-set PF07654.15 KFO99649.1 - 0.038 14.4 0.1 0.64 10.4 0.0 3.0 4 0 0 4 4 4 0 Immunoglobulin C1-set domain Marek_A PF02124.15 KFO99649.1 - 0.047 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Marek's disease glycoprotein A SANTA PF09133.10 KFO99650.1 - 7.9e-29 100.0 0.1 8.9e-29 99.8 0.1 1.0 1 0 0 1 1 1 1 SANTA (SANT Associated) Myb_DNA-binding PF00249.31 KFO99651.1 - 0.0033 17.6 0.1 0.0066 16.6 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFO99651.1 - 0.069 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain FANCM-MHF_bd PF16783.5 KFO99652.1 - 4.6e-43 146.0 6.2 1.4e-42 144.4 6.2 1.9 1 0 0 1 1 1 1 FANCM to MHF binding domain Helicase_C PF00271.31 KFO99652.1 - 6.2e-19 68.4 0.0 2.5e-18 66.5 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFO99652.1 - 2e-05 24.4 0.0 4.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC4 PF02732.15 KFO99652.1 - 5.9e-05 23.3 1.2 9.6e-05 22.6 0.1 2.0 2 0 0 2 2 2 1 ERCC4 domain ResIII PF04851.15 KFO99652.1 - 9.9e-05 22.4 0.0 0.00033 20.7 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HHH_2 PF12826.7 KFO99652.1 - 0.16 12.1 0.0 0.45 10.7 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif SOUL PF04832.12 KFO99653.1 - 1.9e-36 125.8 0.0 2.1e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein FKBP_C PF00254.28 KFO99654.1 - 2.2e-13 50.4 0.2 4e-10 39.9 0.1 2.3 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase BTHB PF18410.1 KFO99654.1 - 1.3e-10 41.0 0.1 2.4e-10 40.1 0.1 1.4 1 0 0 1 1 1 1 Basic tilted helix bundle domain RNA_pol_Rpc4 PF05132.14 KFO99654.1 - 0.028 14.9 1.4 0.049 14.1 1.4 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 CLASP_N PF12348.8 KFO99655.1 - 1.4e-08 34.6 1.5 4.4e-05 23.1 0.1 3.1 3 0 0 3 3 3 2 CLASP N terminal ParcG PF10274.9 KFO99655.1 - 0.022 14.9 0.9 0.28 11.3 0.4 2.4 2 1 0 2 2 2 0 Parkin co-regulated protein HEAT_2 PF13646.6 KFO99655.1 - 0.029 14.8 2.6 2.1 8.8 1.3 3.5 3 0 0 3 3 3 0 HEAT repeats Adaptin_N PF01602.20 KFO99655.1 - 0.069 11.7 2.8 0.086 11.4 0.3 2.3 3 0 0 3 3 3 0 Adaptin N terminal region HEAT PF02985.22 KFO99655.1 - 0.13 12.6 4.1 1e+02 3.6 0.0 5.3 6 0 0 6 6 6 0 HEAT repeat HEAT_EZ PF13513.6 KFO99655.1 - 0.62 10.6 2.6 2.2 8.9 1.9 2.5 2 0 0 2 2 2 0 HEAT-like repeat C2 PF00168.30 KFO99656.1 - 7.7e-12 45.4 0.0 1.1e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 C2 domain PH_6 PF15406.6 KFO99656.1 - 0.053 13.8 0.1 0.21 11.9 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain TSP_3 PF02412.18 KFO99657.1 - 7e-58 192.0 138.2 6.6e-12 44.9 15.4 10.4 8 2 2 10 10 10 8 Thrombospondin type 3 repeat TSP_1 PF00090.19 KFO99657.1 - 4.8e-45 151.6 61.8 6.2e-17 61.6 9.0 5.1 5 0 0 5 5 5 3 Thrombospondin type 1 domain VWC PF00093.18 KFO99657.1 - 5.3e-13 49.1 17.8 5.3e-13 49.1 17.8 6.2 5 1 0 6 6 6 1 von Willebrand factor type C domain TSP_C PF05735.12 KFO99657.1 - 8.5e-08 32.4 0.0 1.3e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Thrombospondin C-terminal region EGF_3 PF12947.7 KFO99657.1 - 2.2e-07 30.9 7.2 2.2e-07 30.9 7.2 5.9 5 0 0 5 5 5 2 EGF domain EGF_CA PF07645.15 KFO99657.1 - 3.9e-06 27.0 1.7 3.9e-06 27.0 1.7 5.7 5 1 0 5 5 5 3 Calcium-binding EGF domain EGF PF00008.27 KFO99657.1 - 0.0028 17.9 8.3 0.0028 17.9 8.3 4.9 4 0 0 4 4 4 1 EGF-like domain cEGF PF12662.7 KFO99657.1 - 0.01 15.8 0.5 0.01 15.8 0.5 5.2 6 0 0 6 6 6 0 Complement Clr-like EGF-like Laminin_G_2 PF02210.24 KFO99657.1 - 0.078 13.6 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain Csm1_B PF18211.1 KFO99659.1 - 0.045 13.6 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 Csm1 subunit domain B DUF1387 PF07139.11 KFO99661.1 - 2.9e-118 395.2 7.2 3.2e-118 395.0 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1387) IRK_N PF08466.10 KFO99661.1 - 0.15 12.2 2.3 0.15 12.2 0.5 1.9 2 0 0 2 2 2 0 Inward rectifier potassium channel N-terminal M_domain PF12938.7 KFO99661.1 - 0.48 10.2 4.6 2.9 7.6 0.0 2.3 2 1 1 3 3 3 0 M domain of GW182 hNIFK_binding PF12196.8 KFO99662.1 - 0.036 13.6 0.1 0.048 13.2 0.1 1.2 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK Tubulin PF00091.25 KFO99663.1 - 1.4e-41 142.9 0.0 1.8e-41 142.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFO99663.1 - 1.9e-14 53.9 0.0 3.1e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFO99663.1 - 0.00079 19.2 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Hormone_recep PF00104.30 KFO99664.1 - 5.9e-21 75.0 0.0 9.1e-21 74.4 0.0 1.3 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor CBS PF00571.28 KFO99665.1 - 2.1e-24 85.7 0.2 6.9e-09 36.0 0.0 4.0 4 0 0 4 4 4 3 CBS domain Cbl_N3 PF02762.14 KFO99665.1 - 0.0034 17.2 0.0 0.0064 16.3 0.0 1.5 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain Arf PF00025.21 KFO99666.1 - 1.3e-30 106.1 0.5 1.5e-30 105.9 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFO99666.1 - 8.8e-07 29.2 0.1 1.1e-06 28.8 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFO99666.1 - 7.8e-06 25.4 0.1 8.7e-06 25.3 0.1 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFO99666.1 - 2e-05 24.0 0.7 0.017 14.3 0.1 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KFO99666.1 - 4.6e-05 23.1 0.2 5.5e-05 22.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KFO99666.1 - 9.4e-05 21.9 0.0 0.00011 21.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region 6PF2K PF01591.18 KFO99666.1 - 0.0031 16.9 0.2 0.0032 16.8 0.2 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase MMR_HSR1 PF01926.23 KFO99666.1 - 0.024 14.7 0.1 0.036 14.2 0.1 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 KFO99666.1 - 0.21 11.7 0.0 0.22 11.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain FKBP_C PF00254.28 KFO99667.1 - 4e-13 49.5 0.0 6.1e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Cyclin_N PF00134.23 KFO99668.1 - 5.7e-16 58.4 1.3 9.7e-13 48.0 0.2 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain UPF0253 PF06786.12 KFO99668.1 - 0.13 12.5 0.3 0.34 11.2 0.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0253) zf-C3Hc3H PF13891.6 KFO99669.1 - 2.6e-17 62.9 5.0 4.9e-17 62.0 5.0 1.5 1 0 0 1 1 1 1 Potential DNA-binding domain zf-TRM13_CCCH PF11722.8 KFO99669.1 - 0.00016 21.3 11.2 0.012 15.3 1.0 3.3 3 1 0 3 3 3 2 CCCH zinc finger in TRM13 protein WRC PF08879.10 KFO99669.1 - 0.036 13.8 1.0 0.25 11.0 0.2 2.5 2 0 0 2 2 2 0 WRC zf-C3Hc3H PF13891.6 KFO99670.1 - 2.4e-15 56.6 7.7 3.6e-15 56.1 7.7 1.3 1 0 0 1 1 1 1 Potential DNA-binding domain ATG101 PF07855.12 KFO99671.1 - 3.8e-42 143.9 0.0 5e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 Pkinase_Tyr PF07714.17 KFO99672.1 - 2.7e-36 125.2 0.0 2.4e-35 122.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO99672.1 - 1.4e-34 119.7 0.0 2.7e-34 118.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.12 KFO99672.1 - 6.8e-16 57.4 0.1 1.3e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Pkinase_fungal PF17667.1 KFO99672.1 - 0.00077 18.3 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFO99672.1 - 0.015 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFO99672.1 - 0.11 11.5 0.1 0.18 10.7 0.1 1.6 1 1 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KFO99672.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Ank_2 PF12796.7 KFO99673.1 - 3e-17 63.0 0.2 8.1e-17 61.6 0.2 1.7 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFO99673.1 - 5.1e-15 55.3 0.6 1.3e-07 31.7 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFO99673.1 - 2.3e-11 44.0 0.1 0.0001 22.8 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KFO99673.1 - 7.2e-11 42.0 0.5 0.0026 18.1 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KFO99673.1 - 4.1e-09 35.9 0.2 0.00047 20.4 0.1 3.9 4 0 0 4 4 4 2 Ankyrin repeat SLH PF00395.20 KFO99674.1 - 0.15 12.1 0.5 3.7 7.6 0.1 2.3 2 0 0 2 2 2 0 S-layer homology domain Plasmid_RAQPRD PF09686.10 KFO99674.1 - 0.17 12.1 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Methyltransf_11 PF08241.12 KFO99675.1 - 2.4e-16 60.1 0.0 4.3e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFO99675.1 - 3.4e-14 53.0 0.0 4.6e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFO99675.1 - 9.4e-13 48.8 0.0 1.8e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFO99675.1 - 1.9e-11 44.5 0.0 3.1e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFO99675.1 - 4.8e-08 32.9 0.0 7.2e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFO99675.1 - 1.4e-07 31.1 0.0 1.8e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KFO99675.1 - 7.6e-05 22.5 0.0 0.0001 22.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_8 PF05148.15 KFO99675.1 - 0.00018 21.4 0.0 0.00025 21.0 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase DUF4816 PF16086.5 KFO99675.1 - 1.9 8.5 5.0 2.2 8.3 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4816) Trypsin PF00089.26 KFO99677.1 - 2.4e-69 233.6 0.0 2.6e-69 233.4 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFO99677.1 - 9.2e-08 33.1 0.0 1.2e-07 32.8 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFO99677.1 - 0.0031 17.9 0.0 0.0053 17.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) bZIP_1 PF00170.21 KFO99678.1 - 2.9e-21 75.3 9.0 4.7e-21 74.7 9.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor pKID PF02173.17 KFO99678.1 - 1.1e-18 66.4 5.6 3e-18 65.0 5.6 1.8 1 0 0 1 1 1 1 pKID domain bZIP_2 PF07716.15 KFO99678.1 - 6.7e-09 35.7 8.1 1.2e-08 34.9 8.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFO99678.1 - 0.00029 21.3 4.8 0.00065 20.2 4.8 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor ASD2 PF08687.11 KFO99678.1 - 0.0093 15.6 1.8 0.016 14.8 1.8 1.3 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 Rh5 PF18515.1 KFO99678.1 - 0.034 13.4 1.5 0.046 13.0 1.5 1.1 1 0 0 1 1 1 0 Rh5 coiled-coil domain tRNA-synt_1g PF09334.11 KFO99679.1 - 9.3e-149 495.4 0.0 1.2e-148 495.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.20 KFO99679.1 - 2.5e-17 62.8 6.1 4.5e-17 61.9 6.1 1.5 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_1 PF00133.22 KFO99679.1 - 5.7e-08 31.5 0.3 0.0018 16.6 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KFO99679.1 - 0.0043 17.0 0.0 0.0083 16.1 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA GST_C_2 PF13410.6 KFO99679.1 - 0.13 12.3 1.3 0.23 11.5 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain TTSSLRR PF12468.8 KFO99679.1 - 2.8 8.3 6.0 5.5 7.3 1.2 2.4 2 0 0 2 2 2 0 Type III secretion system leucine rich repeat protein bZIP_2 PF07716.15 KFO99680.1 - 0.0089 16.1 3.5 0.018 15.1 3.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KFO99680.1 - 0.039 14.0 0.8 0.079 13.1 0.8 1.5 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.15 KFO99680.1 - 0.077 12.8 1.8 0.16 11.8 1.8 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF1192 PF06698.11 KFO99680.1 - 0.11 12.5 1.3 0.31 11.1 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) CLZ PF16526.5 KFO99680.1 - 0.21 12.0 2.7 0.54 10.7 2.7 1.7 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CP2 PF04516.15 KFO99681.1 - 9.7e-59 198.5 0.0 1.5e-58 197.8 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor SAM_3 PF18016.1 KFO99681.1 - 6.7e-19 67.5 0.0 3e-18 65.4 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DAZAP2 PF11029.8 KFO99682.1 - 9.6e-17 62.1 1.5 1.4e-16 61.6 1.5 1.2 1 0 0 1 1 1 1 DAZ associated protein 2 (DAZAP2) zf-H2C2_2 PF13465.6 KFO99683.1 - 6.1e-15 54.9 24.0 9.8e-08 32.1 3.0 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFO99683.1 - 1.1e-13 50.8 25.8 2.2e-05 24.6 0.8 4.4 3 1 1 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO99683.1 - 2.9e-08 33.9 25.9 0.00034 21.2 1.7 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO99683.1 - 0.01 16.1 3.4 2.1 8.7 0.8 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KFO99683.1 - 0.013 15.8 2.6 0.013 15.8 2.6 2.1 2 0 0 2 2 2 0 C2H2-type zinc ribbon DUF390 PF04094.14 KFO99683.1 - 1.1 7.4 8.6 2 6.6 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF390) zf-C2H2_6 PF13912.6 KFO99683.1 - 6.1 7.0 20.7 0.28 11.2 0.2 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger zf-Di19 PF05605.12 KFO99683.1 - 7.8 6.9 13.9 4.5 7.7 3.1 3.2 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KFO99684.1 - 2.5e-17 62.3 15.6 3.6e-06 27.1 4.5 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO99684.1 - 1.6e-14 53.5 18.6 6e-08 32.8 2.3 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFO99684.1 - 3e-11 43.2 14.9 0.00019 22.0 3.2 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO99684.1 - 1.3e-06 28.5 4.0 0.04 14.2 1.5 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFO99684.1 - 0.00016 22.0 4.3 0.13 12.7 0.8 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-LYAR PF08790.11 KFO99684.1 - 0.001 18.9 6.6 0.012 15.6 0.6 2.7 3 0 0 3 3 3 2 LYAR-type C2HC zinc finger zf-BED PF02892.15 KFO99684.1 - 0.0017 18.4 11.5 0.015 15.3 2.7 3.1 2 1 1 3 3 3 1 BED zinc finger zf-C2H2_8 PF15909.5 KFO99684.1 - 0.015 15.6 3.3 0.016 15.5 3.3 1.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon DUF4187 PF13821.6 KFO99684.1 - 0.015 15.1 0.3 2 8.3 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4187) zf-C2H2_2 PF12756.7 KFO99684.1 - 0.02 15.2 3.6 0.75 10.2 0.9 2.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Zn-C2H2_12 PF18112.1 KFO99684.1 - 0.021 15.3 3.4 0.39 11.2 0.1 3.1 3 2 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_6 PF13912.6 KFO99684.1 - 0.037 14.0 15.8 0.38 10.8 0.1 3.3 3 1 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 KFO99684.1 - 0.048 14.0 1.7 0.048 14.0 1.7 2.1 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding ARS2 PF04959.13 KFO99684.1 - 0.053 13.9 0.6 0.064 13.6 0.6 1.1 1 0 0 1 1 1 0 Arsenite-resistance protein 2 zf-C2H2_3rep PF18868.1 KFO99684.1 - 0.056 14.1 4.7 0.56 10.9 1.3 2.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 KFO99684.1 - 0.064 13.0 11.5 0.15 11.9 1.9 2.8 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KFO99684.1 - 0.096 12.5 0.5 0.096 12.5 0.5 3.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf_C2H2_ZHX PF18387.1 KFO99684.1 - 1.2 8.9 5.7 0.6 9.8 0.4 2.6 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain ANAPC4_WD40 PF12894.7 KFO99685.1 - 2.4e-10 40.6 0.2 0.063 13.6 0.0 5.4 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFO99685.1 - 1.1e-07 32.4 7.3 0.00051 20.8 0.0 5.2 6 0 0 6 6 6 2 WD domain, G-beta repeat eIF2A PF08662.11 KFO99685.1 - 3.7e-06 26.9 0.0 0.031 14.1 0.0 3.4 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KFO99685.1 - 7.9e-05 22.5 0.7 0.37 10.8 0.1 3.8 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat WDCP PF15390.6 KFO99685.1 - 0.0021 16.5 8.0 0.18 10.1 3.8 2.6 1 1 1 2 2 2 2 WD repeat and coiled-coil-containing protein family zf-C4 PF00105.18 KFO99686.1 - 1.9e-28 98.7 15.8 3.1e-28 98.0 15.8 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFO99686.1 - 8.1e-22 77.8 1.1 1.1e-21 77.4 0.2 1.6 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-RRPl_C4 PF17026.5 KFO99686.1 - 0.087 12.9 3.1 0.15 12.2 3.1 1.4 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Bromodomain PF00439.25 KFO99687.1 - 8.1e-43 144.4 1.0 2.3e-21 75.6 0.1 2.4 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KFO99687.1 - 5.6e-29 100.1 0.2 5.6e-29 100.1 0.2 2.3 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Sigma70_ner PF04546.13 KFO99687.1 - 0.00094 19.1 12.0 0.00094 19.1 12.0 1.9 2 0 0 2 2 2 1 Sigma-70, non-essential region CDC45 PF02724.14 KFO99687.1 - 0.018 13.4 16.1 0.028 12.7 16.1 1.3 1 0 0 1 1 1 0 CDC45-like protein SelK_SelG PF10961.8 KFO99687.1 - 0.024 15.2 2.5 0.064 13.9 2.5 1.8 1 0 0 1 1 1 0 Selenoprotein SelK_SelG SGT1 PF07093.11 KFO99687.1 - 0.1 11.0 9.9 0.16 10.4 9.9 1.2 1 0 0 1 1 1 0 SGT1 protein DNA_pol_phi PF04931.13 KFO99687.1 - 0.14 10.2 22.8 0.27 9.3 22.8 1.4 1 0 0 1 1 1 0 DNA polymerase phi GCIP PF13324.6 KFO99687.1 - 0.14 11.7 6.6 0.25 10.9 6.6 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting RRN3 PF05327.11 KFO99687.1 - 0.15 10.6 10.9 0.24 9.9 10.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Enkurin PF13864.6 KFO99687.1 - 3.1 8.3 19.6 3 8.3 9.5 3.2 3 0 0 3 3 2 0 Calmodulin-binding Allexi_40kDa PF05549.11 KFO99687.1 - 3.2 7.2 6.6 8.7 5.8 6.6 1.7 1 0 0 1 1 1 0 Allexivirus 40kDa protein BSP_II PF05432.11 KFO99687.1 - 4.3 7.0 27.2 9.1 5.9 27.2 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FlxA PF14282.6 KFO99687.1 - 4.5 7.3 21.3 0.073 13.1 7.5 3.7 3 1 0 3 3 3 0 FlxA-like protein Hid1 PF12722.7 KFO99687.1 - 5.6 5.0 8.5 7.6 4.5 8.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pes-10 PF07149.11 KFO99687.1 - 9 5.2 12.8 16 4.4 12.8 1.3 1 0 0 1 1 1 0 Pes-10 C1-set PF07654.15 KFO99688.1 - 2.6e-18 66.2 0.0 3.6e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin C1-set domain C2-set_2 PF08205.12 KFO99688.1 - 9.7e-05 22.4 0.0 0.00014 21.8 0.0 1.2 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ribosomal_S7 PF00177.21 KFO99689.1 - 1.4e-06 28.0 0.1 1.7e-06 27.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Abhydrolase_1 PF00561.20 KFO99689.1 - 0.16 11.5 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ribosomal_S7 PF00177.21 KFO99690.1 - 6.7e-16 58.3 0.4 7.2e-16 58.2 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e 7tm_3 PF00003.22 KFO99691.1 - 3.3e-27 95.7 0.1 9.5e-18 64.8 0.1 2.2 2 0 0 2 2 2 2 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 KFO99691.1 - 9.3e-23 80.9 0.0 6e-16 58.5 0.0 2.6 2 1 1 3 3 3 2 Receptor family ligand binding region DUF3995 PF13160.6 KFO99691.1 - 0.017 15.4 0.0 0.049 14.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) PKcGMP_CC PF16808.5 KFO99691.1 - 0.15 11.9 8.2 0.38 10.6 8.2 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4407 PF14362.6 KFO99691.1 - 0.22 10.8 3.5 0.39 10.0 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LRRC37AB_C PF14914.6 KFO99691.1 - 0.34 10.8 3.5 2.7 7.9 0.0 2.4 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain KxDL PF10241.9 KFO99691.1 - 0.41 11.0 4.0 1.1 9.6 4.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein TctB PF07331.11 KFO99691.1 - 0.8 10.0 9.1 0.64 10.3 0.7 3.0 2 2 1 3 3 3 0 Tripartite tricarboxylate transporter TctB family SH3BP5 PF05276.14 KFO99692.1 - 2.4e-89 299.1 26.2 2.8e-89 298.9 26.2 1.0 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) Folliculin PF11704.8 KFO99692.1 - 0.11 12.3 1.9 0.22 11.4 1.9 1.6 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Hydrolase_3 PF08282.12 KFO99692.1 - 0.12 12.1 0.7 0.19 11.4 0.7 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase LemA PF04011.12 KFO99692.1 - 0.29 11.0 13.3 0.048 13.5 4.9 2.6 2 1 0 2 2 2 0 LemA family NDUFA12 PF05071.16 KFO99692.1 - 0.48 11.3 1.9 0.89 10.4 1.5 1.6 1 1 0 1 1 1 0 NADH ubiquinone oxidoreductase subunit NDUFA12 Perilipin PF03036.16 KFO99692.1 - 0.63 9.0 13.4 0.94 8.4 13.4 1.4 1 0 0 1 1 1 0 Perilipin family DUF3772 PF12607.8 KFO99692.1 - 0.82 9.5 4.9 5.3 6.9 1.4 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3772) Phage_GP20 PF06810.11 KFO99692.1 - 1.2 8.9 10.9 0.53 10.1 5.2 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 T3SSipB PF16535.5 KFO99692.1 - 3.8 8.0 14.7 0.25 11.8 4.7 2.7 1 1 1 2 2 2 0 Type III cell invasion protein SipB TACC_C PF05010.14 KFO99692.1 - 4.7 6.9 20.8 8.1 6.2 14.7 2.6 1 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal HEAT_PBS PF03130.16 KFO99693.1 - 9.7 7.2 9.3 6.1 7.8 3.3 3.6 3 1 0 3 3 3 0 PBS lyase HEAT-like repeat zf-H2C2_2 PF13465.6 KFO99694.1 - 1.1e-70 231.1 76.7 1.5e-08 34.7 0.9 13.1 13 0 0 13 13 13 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFO99694.1 - 2.5e-68 222.9 82.2 3.2e-07 30.4 3.9 12.3 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO99694.1 - 9.7e-36 119.4 77.1 0.0013 19.3 0.2 12.2 12 0 0 12 12 12 10 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFO99694.1 - 6.1e-15 54.7 55.9 0.027 14.2 0.5 11.9 12 0 0 12 12 12 6 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFO99694.1 - 3.1e-14 52.8 28.6 0.06 13.7 0.0 11.2 12 0 0 12 12 11 4 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFO99694.1 - 6.6e-12 44.8 44.4 0.59 9.8 0.1 11.8 12 0 0 12 12 12 5 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFO99694.1 - 1.1e-09 38.3 66.2 0.026 14.7 3.0 9.7 4 3 5 10 10 10 7 Zinc ribbon domain XPA_N PF01286.18 KFO99694.1 - 2.2e-08 34.0 43.1 6.7 6.8 0.5 12.0 12 0 0 12 12 12 1 XPA protein N-terminal zf-C2H2_6 PF13912.6 KFO99694.1 - 9.3e-08 31.9 84.3 0.0045 17.0 0.4 12.3 12 1 0 12 12 12 5 C2H2-type zinc finger DNA_RNApol_7kD PF03604.13 KFO99694.1 - 2.6e-07 30.2 53.5 0.33 10.7 0.1 12.0 12 0 0 12 12 12 6 DNA directed RNA polymerase, 7 kDa subunit zf-trcl PF13451.6 KFO99694.1 - 1.5e-06 28.0 49.5 2.1 8.3 0.0 11.3 11 2 0 11 11 11 3 Probable zinc-ribbon domain ADK_lid PF05191.14 KFO99694.1 - 1.1e-05 25.4 40.0 0.08 12.9 0.1 8.1 6 2 1 7 7 7 3 Adenylate kinase, active site lid C1_4 PF07975.12 KFO99694.1 - 1.2e-05 25.5 38.3 0.21 11.8 0.3 8.4 2 2 4 8 8 8 4 TFIIH C1-like domain Zn_ribbon_SprT PF17283.2 KFO99694.1 - 1.4e-05 24.9 52.6 0.12 12.3 0.8 9.7 5 5 4 9 9 9 3 SprT-like zinc ribbon domain zinc_ribbon_15 PF17032.5 KFO99694.1 - 0.00029 21.5 36.7 0.56 11.0 0.8 6.5 1 1 7 8 8 8 4 zinc-ribbon family DUF3268 PF11672.8 KFO99694.1 - 0.0019 18.5 30.0 0.2 12.0 1.1 6.1 4 2 2 6 6 6 3 zinc-finger-containing domain HalOD2 PF18547.1 KFO99694.1 - 0.0027 17.6 51.4 0.13 12.1 0.1 8.8 7 3 0 7 7 7 3 Halobacterial output domain 2 HypA PF01155.19 KFO99694.1 - 0.0032 17.5 36.5 0.54 10.3 0.3 6.7 2 2 4 6 6 6 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FYDLN_acid PF09538.10 KFO99694.1 - 0.0034 18.1 22.9 7.7 7.3 1.7 9.0 2 2 9 11 11 11 0 Protein of unknown function (FYDLN_acid) zf-LYAR PF08790.11 KFO99694.1 - 0.012 15.4 45.5 1.6 8.7 0.7 11.4 12 0 0 12 12 12 0 LYAR-type C2HC zinc finger DUF3656 PF12392.8 KFO99694.1 - 0.068 13.8 0.0 70 4.1 0.0 3.8 2 2 2 4 4 4 0 Collagenase FAM209 PF15206.6 KFO99694.1 - 0.069 12.9 0.1 11 5.8 0.0 2.4 2 0 0 2 2 2 0 FAM209 family zf-Di19 PF05605.12 KFO99694.1 - 0.11 12.8 0.2 0.11 12.8 0.2 5.6 6 1 1 7 7 6 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_recom PF13408.6 KFO99694.1 - 0.62 10.6 70.4 8.2 7.0 0.2 10.8 4 2 7 11 11 10 0 Recombinase zinc beta ribbon domain BolA PF01722.18 KFO99694.1 - 7.5 6.9 13.3 24 5.3 1.1 4.4 4 1 1 5 5 5 0 BolA-like protein zf-H2C2_2 PF13465.6 KFO99695.1 - 5.8e-11 42.3 6.4 6.8e-08 32.6 0.6 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFO99695.1 - 1.9e-07 31.2 5.8 2.2e-06 27.8 1.5 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO99695.1 - 0.0022 18.7 1.0 0.0022 18.7 1.0 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFO99695.1 - 0.0069 16.1 0.0 0.0098 15.6 0.0 1.3 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-trcl PF13451.6 KFO99695.1 - 0.023 14.6 0.1 0.03 14.2 0.1 1.2 1 0 0 1 1 1 0 Probable zinc-ribbon domain zf-C2H2_6 PF13912.6 KFO99695.1 - 1.3 9.1 10.0 0.99 9.5 5.1 2.5 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFO99696.1 - 2.8e-49 162.9 63.5 1.1e-05 25.6 1.3 9.1 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO99696.1 - 3e-47 157.0 67.5 9.4e-08 32.1 1.2 10.7 10 1 0 10 10 10 8 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFO99696.1 - 2.2e-33 112.0 61.3 0.0002 21.9 1.6 9.1 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO99696.1 - 1.4e-14 53.9 18.7 0.064 13.6 0.0 9.3 9 0 0 9 9 9 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFO99696.1 - 3.3e-11 42.9 60.9 0.001 19.0 0.9 10.0 9 1 0 9 9 9 5 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFO99696.1 - 5.1e-10 39.3 35.1 0.0075 16.4 0.6 8.0 6 2 2 8 8 8 4 Zinc ribbon domain zf_UBZ PF18439.1 KFO99696.1 - 3.2e-08 33.0 25.8 2.5 7.8 0.1 8.6 9 0 0 9 9 9 2 Ubiquitin-Binding Zinc Finger zf-LYAR PF08790.11 KFO99696.1 - 2.3e-07 30.6 29.5 2.7 8.0 0.2 9.1 9 0 0 9 9 9 2 LYAR-type C2HC zinc finger zf-C2H2_11 PF16622.5 KFO99696.1 - 2.1e-06 27.4 45.8 0.23 11.2 1.4 9.1 9 0 0 9 9 9 4 zinc-finger C2H2-type XPA_N PF01286.18 KFO99696.1 - 0.00013 21.9 32.8 5.3 7.2 0.0 8.9 9 0 0 9 9 9 1 XPA protein N-terminal HypA PF01155.19 KFO99696.1 - 0.00023 21.2 16.4 0.82 9.7 0.4 4.8 1 1 4 5 5 5 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_8 PF15909.5 KFO99696.1 - 0.00082 19.6 17.7 0.33 11.3 0.5 4.4 2 1 2 4 4 4 3 C2H2-type zinc ribbon C1_4 PF07975.12 KFO99696.1 - 0.0013 18.9 23.9 3.9 7.8 0.0 6.7 2 2 4 7 7 7 2 TFIIH C1-like domain FYDLN_acid PF09538.10 KFO99696.1 - 0.0017 19.0 11.2 0.49 11.1 0.3 6.4 2 2 3 6 6 6 1 Protein of unknown function (FYDLN_acid) zinc_ribbon_15 PF17032.5 KFO99696.1 - 0.0027 18.4 18.2 3.3 8.5 0.2 5.1 1 1 3 5 5 5 1 zinc-ribbon family LIM PF00412.22 KFO99696.1 - 0.0031 17.7 24.5 1.7 8.9 0.8 7.2 4 4 0 5 5 5 2 LIM domain zf-trcl PF13451.6 KFO99696.1 - 0.0035 17.2 35.7 0.98 9.4 0.1 8.1 8 1 0 8 8 8 2 Probable zinc-ribbon domain CpXC PF14353.6 KFO99696.1 - 0.019 15.0 23.0 8.1 6.5 0.1 7.4 5 2 2 7 7 7 0 CpXC protein DUF2256 PF10013.9 KFO99696.1 - 0.02 15.0 36.2 0.2 11.8 0.4 8.3 9 0 0 9 9 9 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-met PF12874.7 KFO99696.1 - 0.026 14.9 36.5 3 8.4 0.0 8.4 9 0 0 9 9 9 0 Zinc-finger of C2H2 type zf-AN1 PF01428.16 KFO99696.1 - 0.034 14.3 52.3 3.5 7.9 0.1 9.3 6 3 3 9 9 9 0 AN1-like Zinc finger zf-C2H2_3rep PF18868.1 KFO99696.1 - 0.079 13.6 21.6 0.33 11.6 0.9 6.1 2 2 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-C2HE PF16278.5 KFO99696.1 - 0.15 12.5 33.0 0.96 9.9 0.1 7.6 4 3 3 8 8 7 0 C2HE / C2H2 / C2HC zinc-binding finger zf-Di19 PF05605.12 KFO99696.1 - 0.15 12.3 0.2 0.15 12.3 0.2 5.2 6 1 1 7 7 5 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_7 PF02591.15 KFO99696.1 - 0.23 11.7 0.2 0.23 11.7 0.2 4.5 5 0 0 5 5 3 0 C4-type zinc ribbon domain DNA_RNApol_7kD PF03604.13 KFO99696.1 - 0.24 11.1 38.1 2.6 7.8 0.1 8.1 9 0 0 9 9 9 0 DNA directed RNA polymerase, 7 kDa subunit TFIIS_C PF01096.18 KFO99696.1 - 0.37 10.7 28.8 6.5 6.7 0.0 8.6 9 0 0 9 9 9 0 Transcription factor S-II (TFIIS) zinc_ribbon_4 PF13717.6 KFO99696.1 - 0.39 10.7 27.3 20 5.2 0.0 8.5 9 0 0 9 9 9 0 zinc-ribbon domain BolA PF01722.18 KFO99696.1 - 0.72 10.2 7.6 10 6.5 0.1 3.9 3 1 1 4 4 4 0 BolA-like protein zf-Mss51 PF13824.6 KFO99696.1 - 1.9 8.6 47.7 8.8 6.5 1.3 8.1 2 1 6 8 8 8 0 Zinc-finger of mitochondrial splicing suppressor 51 DYW_deaminase PF14432.6 KFO99696.1 - 5.5 6.9 6.0 1.2e+02 2.5 0.0 3.9 3 1 1 4 4 4 0 DYW family of nucleic acid deaminases RVT_1 PF00078.27 KFO99698.1 - 0.00016 21.2 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.11 KFO99698.1 - 0.26 11.0 0.6 0.43 10.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) Ank_2 PF12796.7 KFO99699.1 - 1.2e-95 314.2 32.0 1.1e-12 48.3 0.0 7.9 2 2 7 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFO99699.1 - 1.3e-59 197.9 14.9 1.8e-08 34.8 0.0 10.6 4 3 8 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFO99699.1 - 2.4e-57 184.1 15.9 0.00017 21.7 0.0 15.9 15 0 0 15 15 15 13 Ankyrin repeat Ank PF00023.30 KFO99699.1 - 6.6e-57 187.6 17.5 1.5e-06 28.4 0.0 14.6 13 1 1 14 14 14 13 Ankyrin repeat Ank_5 PF13857.6 KFO99699.1 - 7.9e-52 172.6 11.7 8.7e-07 29.1 0.0 12.0 4 4 8 12 12 12 10 Ankyrin repeats (many copies) Ion_trans PF00520.31 KFO99699.1 - 7.3e-16 58.1 18.3 1.1e-15 57.5 18.3 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KFO99699.1 - 0.00035 19.4 20.4 0.0026 16.5 11.9 2.3 1 1 1 2 2 2 2 Polycystin cation channel SchA_CurD PF04486.12 KFO99699.1 - 0.13 12.3 0.0 0.38 10.8 0.0 1.8 1 0 0 1 1 1 0 SchA/CurD like domain TRF PF08558.10 KFO99700.1 - 2.7e-25 89.4 3.7 5.1e-25 88.5 3.7 1.4 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 KFO99700.1 - 3.4e-10 39.9 0.4 3.4e-10 39.9 0.4 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFO99700.1 - 0.00039 20.6 0.1 0.0014 18.8 0.1 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain TPR_14 PF13428.6 KFO99700.1 - 0.028 15.2 0.0 0.077 13.9 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFO99700.1 - 0.093 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TSP_1 PF00090.19 KFO99701.1 - 7.4e-05 22.9 2.7 7.4e-05 22.9 2.7 2.8 2 1 1 3 3 3 1 Thrombospondin type 1 domain Ribosomal_L30_N PF08079.12 KFO99703.1 - 3.2e-27 94.6 17.6 6e-27 93.7 17.6 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KFO99703.1 - 1.4e-25 88.9 1.2 4.1e-25 87.4 1.2 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DUF4798 PF16055.5 KFO99703.1 - 6.1 7.1 8.9 10 6.4 8.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4798) dsrm PF00035.26 KFO99704.1 - 7.1e-50 167.6 2.5 4.4e-13 49.7 0.0 4.7 4 0 0 4 4 4 4 Double-stranded RNA binding motif Staufen_C PF16482.5 KFO99704.1 - 9e-21 74.1 0.5 2.9e-16 59.6 0.3 5.3 5 1 0 5 5 5 1 Staufen C-terminal domain DND1_DSRM PF14709.7 KFO99704.1 - 2e-07 31.1 5.1 0.16 12.3 0.1 5.3 4 2 0 4 4 4 2 double strand RNA binding domain from DEAD END PROTEIN 1 Dicer_dimer PF03368.14 KFO99704.1 - 0.021 15.0 2.2 55 4.0 0.0 4.3 4 0 0 4 4 4 0 Dicer dimerisation domain UQ_con PF00179.26 KFO99705.1 - 3.3e-34 117.5 0.2 3.6e-34 117.4 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KFO99705.1 - 0.016 15.1 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 UEV domain Prok-E2_A PF14457.6 KFO99705.1 - 0.11 12.2 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family A Skp1_POZ PF03931.15 KFO99706.1 - 3.1e-11 43.3 0.0 4.3e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain PTAC PF06130.12 KFO99706.1 - 0.13 12.5 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosphate propanoyltransferase TMEM70 PF06979.12 KFO99707.1 - 1.8e-57 193.4 8.5 2.1e-57 193.2 8.5 1.1 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex E1_DerP2_DerF2 PF02221.15 KFO99708.1 - 4.3e-07 30.4 0.0 5e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 ML domain GST_N_3 PF13417.6 KFO99709.1 - 3.6e-11 43.3 0.0 7.8e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFO99709.1 - 1.1e-10 41.7 0.1 3.1e-10 40.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFO99709.1 - 2.3e-09 37.1 0.0 5.2e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFO99709.1 - 1.7e-08 34.6 0.1 4.9e-08 33.1 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFO99709.1 - 6.1e-08 32.9 0.0 1.5e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFO99709.1 - 1.1e-06 28.8 0.1 3.5e-06 27.1 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF1617 PF07761.12 KFO99709.1 - 0.034 14.2 1.0 0.058 13.5 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1617) DUF3206 PF11472.8 KFO99709.1 - 0.045 13.7 0.0 0.077 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) Fmp27_WPPW PF10359.9 KFO99709.1 - 0.079 11.8 0.1 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain GST_N_4 PF17172.4 KFO99709.1 - 0.12 13.1 0.0 0.47 11.2 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain MCR_C PF04609.12 KFO99709.1 - 0.13 11.4 0.2 0.2 10.7 0.2 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C CCDC-167 PF15188.6 KFO99709.1 - 3.8 7.9 7.1 13 6.2 0.2 2.5 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 UNC119_bdg PF15435.6 KFO99710.1 - 4.8e-92 307.0 1.2 5.3e-92 306.8 1.2 1.0 1 0 0 1 1 1 1 UNC119-binding protein C5orf30 homologue SpoU_methylase PF00588.19 KFO99711.1 - 7.4e-31 107.2 0.0 1e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KFO99711.1 - 8.4e-14 51.6 0.0 1.3e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding adh_short PF00106.25 KFO99712.1 - 9.4e-48 162.3 0.1 1.1e-47 162.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFO99712.1 - 1.9e-38 132.4 0.2 2.3e-38 132.1 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFO99712.1 - 5.9e-10 39.3 0.1 7.8e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFO99712.1 - 0.0002 20.9 0.3 0.0015 18.0 0.3 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KFO99712.1 - 0.00091 19.8 0.0 0.026 15.1 0.0 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 KFO99712.1 - 0.0058 16.5 0.1 0.009 15.9 0.1 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFO99712.1 - 0.036 13.6 0.1 0.17 11.4 0.0 2.1 2 1 1 3 3 3 0 NmrA-like family GDP_Man_Dehyd PF16363.5 KFO99712.1 - 0.07 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 KFO99712.1 - 0.096 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AP3D1 PF06375.11 KFO99713.1 - 0.39 10.9 11.8 0.79 9.9 1.5 2.8 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 GWT1 PF06423.12 KFO99714.1 - 7.7e-35 120.2 1.1 3.2e-34 118.2 1.1 2.1 1 0 0 1 1 1 1 GWT1 Myosin_head PF00063.21 KFO99715.1 - 3.7e-199 663.3 0.0 4.9e-199 662.9 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 KFO99715.1 - 0.00027 20.4 10.6 0.0019 17.8 1.2 3.1 3 0 0 3 3 3 2 IQ calmodulin-binding motif AAA_22 PF13401.6 KFO99715.1 - 0.00065 20.0 0.1 0.013 15.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KFO99715.1 - 0.013 15.9 0.4 0.49 10.8 0.0 3.4 4 0 0 4 4 4 0 AAA ATPase domain Microtub_bd PF16796.5 KFO99715.1 - 0.066 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Microtubule binding ParcG PF10274.9 KFO99716.1 - 0.012 15.7 0.0 0.013 15.6 0.0 1.0 1 0 0 1 1 1 0 Parkin co-regulated protein 7tm_1 PF00001.21 KFO99717.1 - 2.5e-26 92.6 20.0 2.8e-26 92.4 20.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MTABC_N PF16185.5 KFO99717.1 - 0.086 12.3 9.3 0.018 14.5 2.6 2.1 1 1 1 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region DUF2418 PF10332.9 KFO99717.1 - 0.39 11.3 6.1 0.13 12.9 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) Carb_anhydrase PF00194.21 KFO99718.1 - 3.5e-88 295.4 0.2 4e-88 295.2 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase UCH PF00443.29 KFO99719.1 - 1.4e-84 283.7 0.0 2.3e-84 282.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KFO99719.1 - 4.5e-26 91.3 0.0 2.3e-25 89.0 0.0 2.4 1 1 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 KFO99719.1 - 1.2e-14 54.7 0.0 6.7e-08 32.5 0.1 3.5 2 2 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase EF-hand_1 PF00036.32 KFO99719.1 - 1.3e-08 33.8 1.1 0.00059 19.2 0.1 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFO99719.1 - 1.7e-08 33.8 0.7 0.024 14.5 0.0 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 KFO99719.1 - 1.8e-08 33.5 3.4 0.00014 21.2 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFO99719.1 - 3.5e-07 30.6 2.0 0.00012 22.5 0.5 2.9 3 0 0 3 3 3 2 EF-hand domain pair Ubiquitin_3 PF14836.6 KFO99719.1 - 1.4e-05 25.0 0.2 3.4e-05 23.7 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_2 PF14560.6 KFO99719.1 - 0.00025 21.4 3.4 0.003 18.0 0.3 2.9 3 0 0 3 3 3 1 Ubiquitin-like domain EF-hand_8 PF13833.6 KFO99719.1 - 0.00027 20.7 3.8 0.26 11.2 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain pair PP2C PF00481.21 KFO99720.1 - 1.2e-60 205.4 0.0 1.6e-60 204.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFO99720.1 - 0.17 11.5 0.0 1 9.0 0.0 2.0 2 0 0 2 2 2 0 Protein phosphatase 2C UBA2_C PF16195.5 KFO99720.1 - 0.22 12.2 2.0 0.46 11.2 2.0 1.5 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus Pneumo_att_G PF05539.11 KFO99720.1 - 4.4 6.8 9.3 6.5 6.2 9.3 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G BCAS3 PF12490.8 KFO99721.1 - 1.5e-28 100.0 0.0 2.4e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 3 WD40 PF00400.32 KFO99721.1 - 0.00012 22.8 1.3 0.021 15.7 0.1 3.1 2 0 0 2 2 2 2 WD domain, G-beta repeat CTP_transf_1 PF01148.20 KFO99721.1 - 0.064 13.0 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase family T-box PF00907.22 KFO99722.1 - 5.3e-37 127.9 2.4 3.2e-33 115.5 0.2 2.2 1 1 1 2 2 2 2 T-box TBX PF12598.8 KFO99722.1 - 0.24 12.2 0.1 0.24 12.2 0.1 2.3 2 0 0 2 2 2 0 T-box transcription factor T-box PF00907.22 KFO99723.1 - 2.1e-68 230.2 0.1 2.4e-68 230.1 0.1 1.0 1 0 0 1 1 1 1 T-box Helicase_C_2 PF13307.6 KFO99724.1 - 2.6e-53 180.7 0.0 5.3e-53 179.7 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KFO99724.1 - 1.7e-50 171.1 0.0 1.7e-50 171.1 0.0 2.7 3 0 0 3 3 3 1 DEAD_2 DEAD PF00270.29 KFO99724.1 - 9.5e-06 25.5 0.0 3.7e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase HBB PF06777.11 KFO99724.1 - 0.00035 20.3 0.0 0.00083 19.1 0.0 1.6 1 0 0 1 1 1 1 Helical and beta-bridge domain ResIII PF04851.15 KFO99724.1 - 0.00051 20.1 0.0 0.15 12.1 0.0 2.9 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit INTS2 PF14750.6 KFO99725.1 - 0 1607.9 21.5 0 1607.7 21.5 1.0 1 0 0 1 1 1 1 Integrator complex subunit 2 Vitellogenin_N PF01347.22 KFO99725.1 - 0.0035 15.8 0.1 0.0063 15.0 0.1 1.3 1 0 0 1 1 1 1 Lipoprotein amino terminal region UPF0052 PF01933.18 KFO99725.1 - 0.096 11.9 0.1 2.9 7.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0052 Med13_C PF06333.12 KFO99726.1 - 1.2e-118 396.2 0.1 1.2e-118 396.2 0.1 4.1 4 1 0 4 4 4 1 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 KFO99726.1 - 1.8e-97 326.0 4.0 1.8e-97 326.0 4.0 3.3 3 1 0 3 3 3 1 MID domain of medPIWI Med13_N PF11597.8 KFO99726.1 - 2.3e-25 89.6 0.0 6.9e-25 88.1 0.0 1.8 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal zf-C3HC4_3 PF13920.6 KFO99727.1 - 1.1e-10 41.2 7.6 1.9e-10 40.4 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFO99727.1 - 8.7e-10 38.8 11.3 2.1e-09 37.6 11.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFO99727.1 - 5.2e-09 35.8 10.5 9.7e-09 34.9 10.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFO99727.1 - 1.6e-08 34.5 7.8 3.6e-08 33.3 7.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFO99727.1 - 1.6e-08 34.2 8.7 2.9e-08 33.4 8.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFO99727.1 - 7e-08 32.3 9.5 1.7e-07 31.1 9.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFO99727.1 - 9.4e-08 31.8 11.7 2e-07 30.7 11.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFO99727.1 - 4e-07 30.2 10.0 8.9e-07 29.1 10.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KFO99727.1 - 3.8e-05 23.8 11.5 7.8e-05 22.7 11.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KFO99727.1 - 0.00018 21.3 3.2 0.0004 20.2 3.2 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 KFO99727.1 - 0.0056 16.3 5.8 0.011 15.3 5.8 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KFO99727.1 - 0.017 15.1 7.4 0.51 10.4 7.4 2.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger GAGA PF09237.11 KFO99727.1 - 0.17 11.7 1.6 8.2 6.3 0.0 2.5 2 0 0 2 2 2 0 GAGA factor DZR PF12773.7 KFO99727.1 - 1.4 9.0 7.0 3.2 7.8 7.0 1.7 1 1 0 1 1 1 0 Double zinc ribbon CTU2 PF10288.9 KFO99727.1 - 1.6 9.0 5.4 38 4.6 5.4 2.1 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-Nse PF11789.8 KFO99727.1 - 1.8 8.5 7.9 3.2 7.6 7.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.14 KFO99727.1 - 2.6 7.8 8.6 8.2 6.2 8.1 2.1 1 1 1 2 2 2 0 P-11 zinc finger zf-RING_11 PF17123.5 KFO99727.1 - 3 7.7 10.0 7.7 6.4 10.0 1.7 1 0 0 1 1 1 0 RING-like zinc finger Macoilin PF09726.9 KFO99727.1 - 4.2 5.8 7.6 6.1 5.3 7.6 1.2 1 0 0 1 1 1 0 Macoilin family Pkinase PF00069.25 KFO99728.1 - 7.2e-70 235.4 0.0 1.3e-69 234.5 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO99728.1 - 5.2e-37 127.5 0.0 6.7e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KFO99728.1 - 3e-10 40.6 3.7 7.4e-10 39.4 3.7 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFO99728.1 - 2e-07 30.6 0.0 6.6e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFO99728.1 - 0.00018 20.4 0.1 0.00028 19.8 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KFO99728.1 - 0.036 13.7 0.1 5 6.7 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFO99728.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFO99728.1 - 0.19 10.6 0.1 0.28 10.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KFO99728.1 - 0.25 10.7 0.2 0.4 10.0 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tubulin PF00091.25 KFO99729.1 - 5.5e-57 193.2 0.0 7.3e-57 192.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 KFO99729.1 - 0.0031 16.8 0.0 0.0057 15.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin like MTP18 PF10558.9 KFO99729.1 - 0.09 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) PTH2 PF01981.16 KFO99730.1 - 1.1e-38 132.1 0.0 1.4e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Clathrin PF00637.20 KFO99731.1 - 1.3e-208 683.2 39.9 1.8e-34 118.7 1.4 7.9 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KFO99731.1 - 3e-50 166.2 3.1 3.1e-08 33.5 0.0 6.7 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 KFO99731.1 - 1.1e-32 111.7 0.4 7.1e-32 109.1 0.3 2.6 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.10 KFO99731.1 - 1e-14 53.5 0.7 3.1e-14 52.0 0.7 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 KFO99731.1 - 1.6e-07 30.8 4.8 1.4e-05 24.4 0.3 4.0 4 0 0 4 4 4 1 Coatomer WD associated region TPR_7 PF13176.6 KFO99731.1 - 0.00011 22.0 11.4 1.5 9.1 0.1 8.1 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFO99731.1 - 0.00045 20.7 3.9 4.1 8.0 0.1 6.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFO99731.1 - 0.00097 18.9 7.2 0.27 11.1 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFO99731.1 - 0.0049 16.9 8.9 4.5 7.6 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFO99731.1 - 0.016 16.0 22.5 24 6.1 0.0 9.2 8 1 1 9 9 8 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO99731.1 - 0.04 14.1 3.1 12 6.2 0.1 5.3 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Ovate PF04844.13 KFO99731.1 - 0.28 11.2 1.6 1.4 9.0 0.0 2.9 3 0 0 3 3 3 0 Transcriptional repressor, ovate HA2 PF04408.23 KFO99732.1 - 2.2e-15 56.9 0.7 4.7e-15 55.8 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFO99732.1 - 1.7e-13 50.7 0.0 3.3e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFO99732.1 - 3.2e-13 50.0 0.0 7.1e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4685 PF15737.5 KFO99732.1 - 4.2e-05 24.0 1.5 0.13 12.7 0.7 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4685) DEAD PF00270.29 KFO99732.1 - 0.00039 20.2 0.0 0.0011 18.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Yippee-Mis18 PF03226.14 KFO99733.1 - 2.7e-12 46.8 0.0 3.5e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-CHY PF05495.12 KFO99733.1 - 0.0097 16.4 3.3 0.1 13.1 0.8 2.1 2 0 0 2 2 2 1 CHY zinc finger Evr1_Alr PF04777.13 KFO99733.1 - 0.023 15.1 0.3 0.28 11.7 0.1 2.0 2 0 0 2 2 2 0 Erv1 / Alr family GDPD PF03009.17 KFO99734.1 - 1e-30 107.4 0.2 3e-23 82.9 0.1 2.0 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KFO99734.1 - 0.0036 17.7 0.0 0.0081 16.6 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Smg8_Smg9 PF10220.9 KFO99735.1 - 0 1139.6 0.0 0 1139.5 0.0 1.0 1 0 0 1 1 1 1 Smg8_Smg9 SKA2 PF16740.5 KFO99736.1 - 5.8e-27 93.7 4.0 6.3e-27 93.5 4.0 1.0 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 zf-B_box PF00643.24 KFO99737.1 - 6.9e-09 35.7 8.7 6.9e-09 35.7 8.7 3.0 2 1 1 3 3 2 1 B-box zinc finger MATH PF00917.26 KFO99737.1 - 7.5e-09 35.7 0.0 2.4e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 MATH domain zf-C3HC4_3 PF13920.6 KFO99737.1 - 1.9e-05 24.4 15.1 1.9e-05 24.4 15.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFO99737.1 - 0.0035 17.1 17.1 0.0035 17.1 17.1 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) HlyD_2 PF12700.7 KFO99737.1 - 0.012 14.4 4.7 0.021 13.6 4.7 1.3 1 0 0 1 1 1 0 HlyD family secretion protein Baculo_PEP_C PF04513.12 KFO99737.1 - 0.055 13.5 4.9 1.1 9.3 2.0 3.3 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.12 KFO99737.1 - 0.13 10.8 2.8 0.27 9.7 2.8 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family MRFAP1 PF15155.6 KFO99737.1 - 0.22 12.1 4.0 0.17 12.4 1.4 2.1 2 0 0 2 2 2 0 MORF4 family-associated protein1 DUF2203 PF09969.9 KFO99737.1 - 0.32 11.7 3.6 29 5.4 2.6 3.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF148 PF02520.17 KFO99737.1 - 0.85 9.8 9.3 0.98 9.6 2.3 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF148 DUF5071 PF16804.5 KFO99737.1 - 2.7 8.3 5.3 34 4.7 5.4 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5071) PIN_8 PF18476.1 KFO99737.1 - 3.6 7.4 10.3 0.16 11.8 1.9 2.6 3 0 0 3 3 3 0 PIN like domain Spc7 PF08317.11 KFO99737.1 - 7.6 5.3 16.1 32 3.2 0.1 2.8 2 1 0 2 2 2 0 Spc7 kinetochore protein PP2C PF00481.21 KFO99738.1 - 2.4e-64 217.5 0.2 3.3e-64 217.0 0.2 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFO99738.1 - 0.0025 17.5 0.1 0.0074 16.0 0.1 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KFO99738.1 - 0.0095 15.9 0.7 1.1 9.1 0.1 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PRIMA1 PF16101.5 KFO99738.1 - 0.18 11.9 7.0 2.2 8.3 7.5 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Rad51 PF08423.11 KFO99739.1 - 1.3e-44 152.4 0.0 1.9e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KFO99739.1 - 1.7e-07 31.0 0.0 3.9e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 KFO99739.1 - 6.1e-05 22.5 0.1 0.00012 21.5 0.1 1.5 1 0 0 1 1 1 1 KaiC RecA PF00154.21 KFO99739.1 - 0.00025 20.6 0.1 0.0035 16.8 0.1 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein DnaB_C PF03796.15 KFO99739.1 - 0.0042 16.4 0.0 0.0075 15.6 0.0 1.4 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_24 PF13479.6 KFO99739.1 - 0.0062 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFO99739.1 - 0.02 15.5 0.0 0.044 14.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KFO99739.1 - 0.042 13.8 0.2 0.17 11.8 0.2 2.0 1 1 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 KFO99739.1 - 0.055 13.8 1.3 1.1 9.5 1.4 2.9 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 KFO99739.1 - 0.14 12.3 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain 7tm_1 PF00001.21 KFO99740.1 - 3.6e-45 154.3 12.2 4.3e-45 154.1 12.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFO99740.1 - 5.4e-07 29.3 10.1 7.6e-07 28.8 10.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.9 KFO99740.1 - 2.7e-05 23.6 5.2 2.7e-05 23.6 5.2 2.1 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 KFO99740.1 - 7.7e-05 22.2 13.0 0.00092 18.7 13.0 2.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFO99740.1 - 0.0001 22.1 12.8 0.0039 17.0 12.8 2.1 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Sru PF10322.9 KFO99740.1 - 0.0039 16.6 5.6 0.0077 15.6 5.6 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sru 7TM_GPCR_Srh PF10318.9 KFO99740.1 - 0.04 12.9 9.3 0.081 11.9 9.3 1.5 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh FAM101 PF15068.6 KFO99741.1 - 3.6e-69 232.9 3.4 3.9e-69 232.7 3.4 1.0 1 0 0 1 1 1 1 FAM101 family Vps53_N PF04100.12 KFO99742.1 - 1.8e-171 570.3 0.8 2.9e-171 569.6 0.8 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 KFO99742.1 - 1.7e-07 30.8 1.6 1.7e-07 30.8 1.6 2.1 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex Spc7 PF08317.11 KFO99742.1 - 4.3e-05 22.6 3.5 9.3e-05 21.5 3.5 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein VPS53_C PF16854.5 KFO99742.1 - 0.00073 19.5 6.1 0.001 19.0 0.0 3.2 3 0 0 3 3 3 1 Vacuolar protein sorting-associated protein 53 C-terminus Sec8_exocyst PF04048.14 KFO99742.1 - 0.013 15.4 2.6 0.016 15.1 1.1 2.0 2 0 0 2 2 1 0 Sec8 exocyst complex component specific domain DUF2451 PF10474.9 KFO99742.1 - 0.013 15.3 1.5 0.02 14.7 0.1 2.1 2 0 0 2 2 1 0 Protein of unknown function C-terminus (DUF2451) Laminin_II PF06009.12 KFO99742.1 - 0.019 15.0 6.4 0.02 14.9 4.3 2.1 2 0 0 2 2 2 0 Laminin Domain II DUF4413 PF14372.6 KFO99742.1 - 0.02 15.2 0.2 0.19 12.1 0.0 2.9 3 1 0 3 3 1 0 Domain of unknown function (DUF4413) NBD94 PF16830.5 KFO99742.1 - 0.025 15.0 3.9 0.068 13.6 3.9 1.8 1 0 0 1 1 1 0 Nucleotide-Binding Domain 94 of RH Vps51 PF08700.11 KFO99742.1 - 0.034 14.2 5.7 0.099 12.7 2.0 3.4 2 1 0 2 2 2 0 Vps51/Vps67 LXG PF04740.12 KFO99742.1 - 0.041 13.6 2.9 0.14 11.9 3.0 1.8 1 1 0 1 1 1 0 LXG domain of WXG superfamily GrpE PF01025.19 KFO99742.1 - 0.052 13.2 2.1 0.14 11.8 2.1 1.8 1 0 0 1 1 1 0 GrpE XhlA PF10779.9 KFO99742.1 - 0.073 13.3 7.1 0.058 13.6 2.7 2.8 2 0 0 2 2 2 0 Haemolysin XhlA DUF1664 PF07889.12 KFO99742.1 - 0.088 12.9 10.5 0.98 9.5 3.5 4.4 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 KFO99742.1 - 0.098 12.9 1.6 0.41 10.9 1.6 2.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) MCPsignal PF00015.21 KFO99742.1 - 0.1 12.4 1.2 0.37 10.6 1.2 1.9 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Sec34 PF04136.15 KFO99742.1 - 0.15 11.9 3.1 0.63 9.9 2.5 2.3 2 0 0 2 2 2 0 Sec34-like family BRE1 PF08647.11 KFO99742.1 - 0.21 11.7 4.5 0.77 9.9 4.5 1.9 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase COG5 PF10392.9 KFO99742.1 - 0.23 11.6 2.9 0.23 11.6 0.8 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Tropomyosin PF00261.20 KFO99742.1 - 0.33 10.3 6.5 0.058 12.8 1.4 2.2 3 0 0 3 3 3 0 Tropomyosin BLOC1_2 PF10046.9 KFO99742.1 - 0.75 10.1 5.7 1.6 9.1 2.1 3.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ING PF12998.7 KFO99742.1 - 0.93 10.1 8.5 0.17 12.5 3.6 2.4 3 0 0 3 3 1 0 Inhibitor of growth proteins N-terminal histone-binding CREPT PF16566.5 KFO99742.1 - 1.2 9.3 6.8 1.8 8.7 1.6 3.3 3 1 0 3 3 2 0 Cell-cycle alteration and expression-elevated protein in tumour Snf7 PF03357.21 KFO99742.1 - 1.3 8.6 10.3 0.51 9.9 5.6 2.5 2 0 0 2 2 2 0 Snf7 Seryl_tRNA_N PF02403.22 KFO99742.1 - 1.3 9.2 8.9 0.27 11.5 3.1 2.7 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain HrpB7 PF09486.10 KFO99742.1 - 2.3 8.6 5.8 1.9 8.8 2.6 2.4 2 1 1 3 3 2 0 Bacterial type III secretion protein (HrpB7) Prefoldin PF02996.17 KFO99742.1 - 3.1 7.7 7.5 18 5.3 1.5 3.6 2 1 2 4 4 4 0 Prefoldin subunit Syntaxin_2 PF14523.6 KFO99742.1 - 4.9 7.6 9.0 6 7.3 5.3 3.1 2 1 0 2 2 1 0 Syntaxin-like protein TRAM_LAG1_CLN8 PF03798.16 KFO99743.1 - 1.1e-39 136.2 15.6 1.3e-39 136.0 15.6 1.0 1 0 0 1 1 1 1 TLC domain Oxidored_q4 PF00507.19 KFO99743.1 - 2.7 8.2 7.1 0.42 10.8 0.4 2.4 1 1 3 4 4 4 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 NAAA-beta PF15508.6 KFO99744.1 - 0.066 13.5 0.0 5.5 7.4 0.0 3.1 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Glyoxalase PF00903.25 KFO99745.1 - 0.0085 16.3 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KFO99745.1 - 0.13 12.6 0.0 0.4 11.0 0.0 1.9 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SpoU_methylase PF00588.19 KFO99746.1 - 7.5e-25 87.8 0.0 5.8e-23 81.6 0.0 2.2 1 1 0 1 1 1 1 SpoU rRNA Methylase family Thioredoxin_8 PF13905.6 KFO99747.1 - 5.2e-22 78.0 0.0 2.8e-17 62.8 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KFO99747.1 - 2.2e-10 40.9 0.0 3.6e-07 30.6 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_6 PF13848.6 KFO99747.1 - 8e-08 32.4 0.0 4.4e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin PF00085.20 KFO99747.1 - 8.2e-08 32.2 0.0 0.00017 21.6 0.0 3.6 3 1 1 4 4 4 1 Thioredoxin Redoxin PF08534.10 KFO99747.1 - 9.5e-06 25.4 0.0 2.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 KFO99747.1 - 4.2e-05 23.6 0.0 0.00046 20.3 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 KFO99747.1 - 4.3e-05 23.4 0.0 0.00017 21.5 0.0 1.9 1 1 0 1 1 1 1 AhpC/TSA family SCO1-SenC PF02630.14 KFO99747.1 - 0.0045 16.9 0.0 0.027 14.4 0.0 2.2 2 0 0 2 2 2 1 SCO1/SenC Glutaredoxin PF00462.24 KFO99747.1 - 0.016 15.4 0.0 0.05 13.8 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin MatE PF01554.18 KFO99748.1 - 1.3e-54 184.2 26.9 4.7e-29 101.1 9.4 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KFO99748.1 - 0.012 15.6 10.3 0.012 15.6 10.3 3.8 3 1 1 4 4 4 0 Polysaccharide biosynthesis C-terminal domain MatE PF01554.18 KFO99749.1 - 3.8e-56 189.2 35.3 1.1e-29 103.1 8.9 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KFO99749.1 - 3.1e-05 24.1 14.1 3.1e-05 24.1 14.1 4.1 2 2 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain CD225 PF04505.12 KFO99749.1 - 0.017 15.2 0.7 0.017 15.2 0.7 4.3 4 0 0 4 4 4 0 Interferon-induced transmembrane protein Aldedh PF00171.22 KFO99750.1 - 2e-83 280.4 0.0 2.3e-83 280.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1196 PF06709.11 KFO99750.1 - 0.0065 16.6 0.1 0.016 15.4 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1196) Aldedh PF00171.22 KFO99751.1 - 2.7e-86 289.9 0.0 3.1e-86 289.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PKcGMP_CC PF16808.5 KFO99751.1 - 0.12 12.2 1.1 0.25 11.2 1.1 1.6 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Pkinase PF00069.25 KFO99752.1 - 1.2e-70 237.9 0.1 3.5e-70 236.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO99752.1 - 3.5e-49 167.4 0.5 5.5e-49 166.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3543 PF12063.8 KFO99752.1 - 1.8e-25 89.8 4.2 3.2e-25 89.0 4.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Kdo PF06293.14 KFO99752.1 - 1.3e-07 31.1 0.1 4.6e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFO99752.1 - 7.5e-06 25.7 0.1 1.4e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KFO99752.1 - 0.00024 20.0 0.2 0.00053 18.9 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KFO99752.1 - 0.0042 16.4 0.0 0.02 14.2 0.0 2.0 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KFO99752.1 - 0.0075 16.2 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family CENP-F_N PF10481.9 KFO99752.1 - 0.27 10.8 2.7 0.56 9.8 2.7 1.4 1 0 0 1 1 1 0 Cenp-F N-terminal domain GATA PF00320.27 KFO99753.1 - 4.4e-28 96.6 21.9 2.4e-15 55.8 5.3 2.7 3 0 0 3 3 3 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KFO99753.1 - 2.4e-06 27.0 6.2 0.014 14.9 1.0 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.18 KFO99753.1 - 0.001 19.1 0.6 0.21 11.7 0.2 2.4 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Zn-ribbon_8 PF09723.10 KFO99753.1 - 0.018 15.1 4.6 0.66 10.1 0.3 3.1 2 1 1 3 3 3 0 Zinc ribbon domain DZR PF12773.7 KFO99753.1 - 0.03 14.4 6.3 2.8 8.0 0.5 2.8 1 1 0 2 2 2 0 Double zinc ribbon eIF-5_eIF-2B PF01873.17 KFO99753.1 - 0.032 14.1 4.3 3 7.8 1.1 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 OrfB_Zn_ribbon PF07282.11 KFO99753.1 - 0.041 13.8 5.3 0.9 9.5 0.3 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Auto_anti-p27 PF06677.12 KFO99753.1 - 0.072 13.3 6.0 0.62 10.3 0.5 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF2387 PF09526.10 KFO99753.1 - 0.15 12.2 5.3 14 5.9 0.3 3.3 1 1 1 3 3 3 0 Probable metal-binding protein (DUF2387) Cytochrom_c3_2 PF14537.6 KFO99753.1 - 0.2 12.2 0.1 0.2 12.2 0.1 2.4 2 1 0 2 2 2 0 Cytochrome c3 zn-ribbon_14 PF16503.5 KFO99753.1 - 0.23 11.0 3.8 17 5.0 0.1 3.4 3 0 0 3 3 3 0 Zinc-ribbon zf-CHY PF05495.12 KFO99753.1 - 0.71 10.4 4.1 13 6.3 0.4 2.4 2 0 0 2 2 2 0 CHY zinc finger Vps36-NZF-N PF16988.5 KFO99753.1 - 1.6 8.2 8.9 0.67 9.4 0.5 3.7 2 2 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Cytochrome_C7 PF14522.6 KFO99753.1 - 2.8 8.0 6.4 12 6.0 6.4 2.1 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Prim_Zn_Ribbon PF08273.12 KFO99753.1 - 3.1 8.1 14.2 0.13 12.6 1.4 3.3 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase Elf1 PF05129.13 KFO99753.1 - 6.1 7.0 8.3 12 6.1 0.1 2.9 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like H2TH PF06831.14 KFO99754.1 - 2.6e-12 46.5 0.0 4.5e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.24 KFO99754.1 - 8e-05 23.2 0.0 0.00014 22.5 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain zf-FPG_IleRS PF06827.14 KFO99754.1 - 0.066 13.1 0.4 0.12 12.2 0.4 1.4 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS POTRA_3 PF17287.2 KFO99754.1 - 0.087 12.3 0.0 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 POTRA domain SQS_PSY PF00494.19 KFO99755.1 - 5.4e-43 147.4 0.0 9e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase HAUS4 PF14735.6 KFO99755.1 - 0.014 15.2 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 Peptidase_C1 PF00112.23 KFO99756.1 - 1.6e-67 227.8 2.3 1.9e-67 227.6 2.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 KFO99756.1 - 2.7e-19 68.8 0.8 5.9e-19 67.7 0.8 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 KFO99756.1 - 0.058 12.2 1.6 2.2 6.9 0.2 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Defensin_beta PF00711.19 KFO99757.1 - 1.3e-10 41.1 11.1 1.5e-10 40.9 11.1 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_big PF14862.6 KFO99757.1 - 0.0063 16.8 3.6 0.0089 16.3 3.6 1.5 1 1 0 1 1 1 1 Big defensin Gamma-thionin PF00304.20 KFO99757.1 - 0.012 15.8 10.3 0.015 15.6 10.3 1.1 1 0 0 1 1 1 0 Gamma-thionin family Defensin_beta_2 PF13841.6 KFO99757.1 - 0.14 12.6 11.1 0.21 12.1 11.1 1.3 1 0 0 1 1 1 0 Beta defensin Defensin_beta PF00711.19 KFO99758.1 - 5e-05 23.2 6.0 6e-05 23.0 6.0 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_beta_2 PF13841.6 KFO99758.1 - 0.00032 21.1 6.4 0.0004 20.8 6.4 1.1 1 0 0 1 1 1 1 Beta defensin m_DGTX_Dc1a_b_c PF17491.2 KFO99758.1 - 0.037 14.7 2.5 0.054 14.2 2.5 1.3 1 1 0 1 1 1 0 Spider Toxins mu-diguetoxin-1 a, b and c Defensin_beta PF00711.19 KFO99759.1 - 3.2e-10 39.8 8.2 3.8e-10 39.6 8.2 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_propep PF00879.18 KFO99759.1 - 0.15 12.3 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Defensin propeptide Defensin_beta PF00711.19 KFO99760.1 - 2.6e-12 46.6 6.1 2.8e-12 46.4 6.1 1.0 1 0 0 1 1 1 1 Beta defensin Defensin_beta PF00711.19 KFO99761.1 - 2.6e-08 33.7 10.2 3.1e-08 33.5 10.2 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_beta PF00711.19 KFO99762.1 - 1.4e-06 28.2 11.8 1.7e-06 27.9 11.8 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_propep PF00879.18 KFO99762.1 - 0.041 14.1 0.0 0.048 13.9 0.0 1.1 1 0 0 1 1 1 0 Defensin propeptide NDK PF00334.19 KFO99763.1 - 1.1e-36 125.9 0.0 1.2e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.18 KFO99763.1 - 0.034 14.7 0.0 0.053 14.1 0.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ Metallophos PF00149.28 KFO99764.1 - 3.5e-18 66.8 0.3 4.2e-18 66.6 0.3 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LRR_8 PF13855.6 KFO99765.1 - 3.7e-32 109.9 14.7 8e-13 48.0 1.7 3.4 2 1 1 3 3 3 3 Leucine rich repeat I-set PF07679.16 KFO99765.1 - 4.1e-15 55.6 0.0 7.1e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO99765.1 - 1.2e-13 51.5 0.0 2.7e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRR_5 PF13306.6 KFO99765.1 - 5e-13 49.1 0.5 4.3e-07 29.9 0.1 2.3 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFO99765.1 - 3.5e-11 43.1 19.3 0.0017 18.7 3.5 4.6 2 1 1 4 4 4 4 Leucine Rich repeats (2 copies) Ig_2 PF13895.6 KFO99765.1 - 2.9e-10 40.3 0.0 5.7e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFO99765.1 - 4.6e-08 33.1 0.0 9.4e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.21 KFO99765.1 - 4e-06 27.1 0.0 9.7e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain LRR_9 PF14580.6 KFO99765.1 - 3.7e-05 23.3 7.4 0.0029 17.1 1.4 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFO99765.1 - 0.0025 18.1 10.7 3.1 8.7 0.3 6.0 6 0 0 6 6 5 1 Leucine Rich Repeat C2-set_2 PF08205.12 KFO99765.1 - 0.0075 16.3 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFO99765.1 - 0.019 15.2 0.0 7.4 6.8 0.0 2.4 1 1 1 2 2 2 0 Immunoglobulin V-set domain Sigma_reg_N PF13800.6 KFO99765.1 - 0.23 11.8 2.1 0.56 10.5 2.1 1.6 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF3139 PF11337.8 KFO99765.1 - 0.24 12.0 3.6 0.8 10.4 3.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) Acyl-CoA_dh_1 PF00441.24 KFO99766.1 - 5.1e-36 124.1 1.7 7e-36 123.7 1.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 KFO99766.1 - 2.1e-19 70.1 2.3 3.1e-19 69.6 2.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFO99766.1 - 1.2e-15 57.5 0.0 2.5e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain IrmA PF18673.1 KFO99766.1 - 0.09 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 interleukin receptor mimic protein A 7tm_4 PF13853.6 KFO99768.1 - 6e-09 36.0 1.6 6.8e-09 35.9 1.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFO99768.1 - 1.2e-05 24.8 0.8 1.4e-05 24.5 0.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CholecysA-Rec_N PF09193.10 KFO99768.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Cholecystokinin A receptor, N-terminal I-set PF07679.16 KFO99769.1 - 5.5e-108 353.3 0.0 1.4e-15 57.1 0.0 11.6 12 0 0 12 12 12 9 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO99769.1 - 1.4e-106 349.3 18.0 4e-14 53.0 0.1 12.0 12 0 0 12 12 12 10 Immunoglobulin domain fn3 PF00041.21 KFO99769.1 - 1.9e-81 268.5 11.6 7.2e-14 51.9 0.0 7.2 7 0 0 7 7 6 6 Fibronectin type III domain Ig_2 PF13895.6 KFO99769.1 - 3.1e-77 254.9 12.8 1.1e-09 38.4 0.0 11.3 11 1 0 11 11 11 10 Immunoglobulin domain ig PF00047.25 KFO99769.1 - 1.7e-68 226.8 1.6 3.3e-11 43.2 0.0 10.7 10 1 0 10 10 10 8 Immunoglobulin domain V-set PF07686.17 KFO99769.1 - 1.4e-30 105.7 9.0 0.0053 16.9 0.0 14.2 11 4 2 13 13 12 6 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFO99769.1 - 3e-17 62.4 1.9 0.089 12.9 0.0 9.1 8 1 1 9 9 9 4 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFO99769.1 - 4.2e-17 61.5 0.2 0.0054 16.3 0.0 6.6 6 0 0 6 6 6 4 Immunoglobulin domain Ig_5 PF16681.5 KFO99769.1 - 1.8e-13 50.7 0.0 0.61 10.5 0.0 8.9 9 1 0 9 9 9 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 KFO99769.1 - 4.1e-10 39.9 0.1 0.012 15.9 0.0 7.5 7 0 0 7 7 7 1 Immunoglobulin C1-set domain Ig_4 PF16680.5 KFO99769.1 - 1.8e-08 34.5 0.0 4.8 7.5 0.0 8.2 9 0 0 9 9 8 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFO99769.1 - 2.5e-08 33.9 0.4 0.64 10.1 0.0 6.8 8 0 0 8 8 8 1 Izumo-like Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFO99769.1 - 1.4e-07 32.0 9.7 1.3 9.7 0.0 7.3 6 1 0 6 6 6 2 Purple acid Phosphatase, N-terminal domain Receptor_2B4 PF11465.8 KFO99769.1 - 1.8e-07 31.3 0.6 0.18 12.0 0.0 5.9 6 0 0 6 6 6 2 Natural killer cell receptor 2B4 V-set_CD47 PF08204.11 KFO99769.1 - 9.9e-07 28.8 0.1 0.012 15.6 0.0 4.9 4 0 0 4 4 4 1 CD47 immunoglobulin-like domain Interfer-bind PF09294.10 KFO99769.1 - 7.3e-06 26.2 0.0 0.46 10.8 0.0 4.4 4 0 0 4 4 4 2 Interferon-alpha/beta receptor, fibronectin type III fn3_2 PF16893.5 KFO99769.1 - 2.2e-05 24.5 0.0 0.053 13.7 0.0 4.2 4 0 0 4 4 4 1 Fibronectin type III domain ChitinaseA_N PF08329.10 KFO99769.1 - 0.0025 17.5 0.0 0.0091 15.6 0.0 1.9 1 0 0 1 1 1 1 Chitinase A, N-terminal domain fn3_4 PF16794.5 KFO99769.1 - 0.013 15.4 0.0 50 3.9 0.0 4.3 4 0 0 4 4 4 0 Fibronectin-III type domain ATP1G1_PLM_MAT8 PF02038.16 KFO99770.1 - 2.9e-27 93.9 0.1 3.5e-27 93.6 0.1 1.1 1 0 0 1 1 1 1 ATP1G1/PLM/MAT8 family EphA2_TM PF14575.6 KFO99770.1 - 0.045 14.6 0.0 0.061 14.2 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Glycophorin_A PF01102.18 KFO99770.1 - 0.17 12.1 0.1 0.24 11.7 0.0 1.3 1 1 0 1 1 1 0 Glycophorin A DUF4668 PF15701.5 KFO99770.1 - 0.17 11.7 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) Trypsin PF00089.26 KFO99771.1 - 1.3e-41 142.8 0.5 1.4e-41 142.7 0.5 1.0 1 0 0 1 1 1 1 Trypsin DUF316 PF03761.15 KFO99771.1 - 0.03 13.9 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 Tissue_fac PF01108.17 KFO99772.1 - 3e-23 81.7 1.1 7.2e-23 80.5 0.0 2.3 2 0 0 2 2 2 1 Tissue factor Interfer-bind PF09294.10 KFO99772.1 - 5.9e-08 33.0 0.2 1.4e-07 31.7 0.2 1.7 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.21 KFO99772.1 - 0.00014 22.1 1.9 0.12 12.7 0.3 2.8 2 0 0 2 2 2 2 Fibronectin type III domain Trypsin PF00089.26 KFO99773.1 - 5.4e-70 235.7 0.1 6.7e-70 235.3 0.1 1.1 1 0 0 1 1 1 1 Trypsin SRCR_2 PF15494.6 KFO99773.1 - 9e-19 67.8 0.3 1.8e-18 66.9 0.3 1.5 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Trypsin_2 PF13365.6 KFO99773.1 - 4.7e-10 40.6 0.0 8.5e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFO99773.1 - 2.1e-06 28.1 0.0 3.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Hepsin-SRCR PF09272.10 KFO99773.1 - 2.2e-06 28.2 2.1 9.7e-06 26.1 2.1 2.0 1 1 0 1 1 1 1 Hepsin, SRCR domain SRCR PF00530.18 KFO99773.1 - 6e-05 23.5 0.1 0.00017 22.1 0.1 1.8 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain YecR PF13992.6 KFO99773.1 - 0.081 13.2 0.1 0.22 11.8 0.1 1.7 1 0 0 1 1 1 0 YecR-like lipoprotein V-set PF07686.17 KFO99774.1 - 8.7e-10 38.8 0.1 1.6e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFO99774.1 - 2.3e-08 34.5 0.1 4.5e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFO99774.1 - 2.7e-06 27.4 0.1 1.6e-05 24.8 0.0 2.3 1 1 1 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 KFO99774.1 - 2.5e-05 24.4 0.2 7.5e-05 22.8 0.2 1.8 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFO99774.1 - 4.5e-05 23.7 0.2 0.00073 19.8 0.2 2.1 1 1 0 1 1 1 1 Immunoglobulin domain Glycophorin_A PF01102.18 KFO99774.1 - 0.0037 17.5 0.5 0.007 16.6 0.4 1.5 1 1 0 1 1 1 1 Glycophorin A Izumo-Ig PF16706.5 KFO99774.1 - 0.02 15.0 0.1 0.11 12.5 0.0 2.2 1 1 1 2 2 2 0 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFO99774.1 - 0.023 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain DUF5436 PF17504.2 KFO99774.1 - 0.066 13.5 4.3 0.19 12.1 4.3 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5436) DUF2483 PF10656.9 KFO99774.1 - 0.081 13.1 0.5 0.19 11.9 0.5 1.5 1 0 0 1 1 1 0 Hypothetical protein of unknown function (DUF2483) TraL PF07178.11 KFO99774.1 - 0.24 11.9 0.8 0.5 10.9 0.8 1.5 1 0 0 1 1 1 0 TraL protein V-set PF07686.17 KFO99775.1 - 7.2e-22 77.6 0.4 1.3e-21 76.8 0.4 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFO99775.1 - 3.5e-07 30.3 0.9 3.5e-07 30.3 0.9 2.1 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFO99775.1 - 9.7e-07 28.8 0.0 3.1e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO99775.1 - 8.2e-05 23.1 0.9 0.00038 21.0 0.9 2.1 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFO99775.1 - 0.00029 21.1 3.8 0.0015 18.8 3.8 1.9 1 1 0 1 1 1 1 Immunoglobulin domain EphA2_TM PF14575.6 KFO99775.1 - 0.00062 20.6 0.0 0.0012 19.7 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 KFO99775.1 - 0.0023 17.8 0.0 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 Syndecan domain Adeno_E3_CR2 PF02439.15 KFO99775.1 - 0.0028 17.4 0.4 0.0053 16.5 0.4 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 PALP PF00291.25 KFO99775.1 - 0.0033 16.9 0.0 0.0044 16.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SKG6 PF08693.10 KFO99775.1 - 0.031 13.7 1.9 0.05 13.0 1.9 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Protocadherin PF08374.11 KFO99775.1 - 0.038 14.0 0.0 0.053 13.5 0.0 1.2 1 0 0 1 1 1 0 Protocadherin Vpu PF00558.19 KFO99775.1 - 0.044 13.6 0.0 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Vpu protein FAM176 PF14851.6 KFO99775.1 - 0.053 13.2 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 FAM176 family Herpes_gE PF02480.16 KFO99775.1 - 0.067 11.9 0.1 0.2 10.4 0.1 1.6 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E Stomagen PF16851.5 KFO99775.1 - 0.081 12.9 1.3 4.5 7.3 0.1 2.4 2 0 0 2 2 2 0 Stomagen TMEM51 PF15345.6 KFO99775.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Mqo PF06039.15 KFO99775.1 - 0.15 10.6 0.0 0.31 9.6 0.0 1.4 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Ig_4 PF16680.5 KFO99775.1 - 0.29 11.4 7.5 2.3 8.6 0.0 2.9 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain V-set PF07686.17 KFO99776.1 - 5.6e-12 45.8 0.1 5e-11 42.7 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_6 PF18452.1 KFO99776.1 - 3.4e-05 23.3 0.0 0.0001 21.8 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin domain DUF4381 PF14316.6 KFO99776.1 - 0.0032 17.7 0.0 0.0053 17.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) ig PF00047.25 KFO99776.1 - 0.026 14.7 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.6 KFO99776.1 - 0.095 13.3 0.0 0.22 12.1 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin domain TMEM223 PF14640.6 KFO99776.1 - 0.22 11.7 0.0 0.29 11.3 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 223 V-set PF07686.17 KFO99778.1 - 5.3e-16 58.8 0.0 7.3e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFO99778.1 - 0.00045 20.3 0.0 0.0017 18.5 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFO99778.1 - 0.0045 17.5 0.0 0.0099 16.5 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFO99778.1 - 0.1 12.9 0.0 2.6 8.5 0.0 2.2 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KFO99779.1 - 5.7e-23 81.2 0.0 7.5e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFO99779.1 - 2.5e-08 34.0 0.1 8.1e-08 32.3 0.0 1.8 2 1 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 KFO99779.1 - 1.8e-06 28.5 0.1 3.2e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFO99779.1 - 4.7e-06 26.6 0.0 9.7e-06 25.6 0.0 1.4 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFO99779.1 - 5.5e-05 23.4 0.2 0.0018 18.5 0.2 2.2 1 1 0 1 1 1 1 Immunoglobulin domain EphA2_TM PF14575.6 KFO99779.1 - 0.01 16.7 0.6 0.017 16.0 0.6 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KFO99779.1 - 0.026 14.4 0.3 0.041 13.8 0.3 1.3 1 0 0 1 1 1 0 TMEM154 protein family Syndecan PF01034.20 KFO99779.1 - 0.033 14.1 0.4 0.071 13.0 0.4 1.5 1 0 0 1 1 1 0 Syndecan domain Protocadherin PF08374.11 KFO99779.1 - 0.097 12.6 2.1 0.24 11.3 1.5 1.8 2 0 0 2 2 2 0 Protocadherin LRRC37AB_C PF14914.6 KFO99779.1 - 0.24 11.3 1.7 0.4 10.6 1.7 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Ig_5 PF16681.5 KFO99780.1 - 3.8e-13 49.7 0.2 6.9e-13 48.8 0.2 1.4 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFO99780.1 - 2.8e-08 33.9 1.8 2.8e-08 33.9 0.3 1.7 2 0 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain FBP_C PF16571.5 KFO99780.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 FBP C-terminal treble-clef zinc-finger Ig_4 PF16680.5 KFO99781.1 - 1e-25 89.8 0.0 1.7e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFO99781.1 - 2e-12 47.3 0.1 3.7e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_2 PF13895.6 KFO99781.1 - 8.5e-05 22.8 0.0 0.00016 21.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ITAM PF02189.15 KFO99781.1 - 0.00027 21.2 0.8 0.00055 20.2 0.8 1.6 1 0 0 1 1 1 1 Immunoreceptor tyrosine-based activation motif Ig_3 PF13927.6 KFO99781.1 - 0.0069 17.0 0.0 0.015 15.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain DAP10 PF07213.11 KFO99781.1 - 0.011 15.7 0.1 0.025 14.5 0.1 1.7 1 0 0 1 1 1 0 DAP10 membrane protein Zw10 PF06248.13 KFO99782.1 - 2.7e-198 660.0 15.9 4.4e-198 659.3 15.9 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Sec8_exocyst PF04048.14 KFO99782.1 - 0.023 14.6 5.8 0.033 14.1 1.2 3.1 3 1 0 3 3 3 0 Sec8 exocyst complex component specific domain Reovirus_M2 PF05993.12 KFO99782.1 - 0.081 11.0 0.0 0.13 10.3 0.0 1.2 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Flagellin_C PF00700.21 KFO99782.1 - 0.41 11.0 5.0 0.23 11.9 0.9 2.6 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region DUF4363 PF14276.6 KFO99782.1 - 0.41 10.8 15.4 6.5 6.9 4.3 4.5 4 1 0 4 4 4 0 Domain of unknown function (DUF4363) Exonuc_VII_L PF02601.15 KFO99782.1 - 0.68 9.4 3.3 1.7 8.1 3.3 1.7 1 0 0 1 1 1 0 Exonuclease VII, large subunit MitMem_reg PF13012.6 KFO99782.1 - 4.6 7.7 6.5 45 4.5 0.3 3.5 3 1 1 4 4 4 0 Maintenance of mitochondrial structure and function 7tm_1 PF00001.21 KFO99783.1 - 1.9e-69 234.0 9.2 2.8e-69 233.4 9.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFO99783.1 - 2.4e-11 43.5 19.1 9e-07 28.5 10.7 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srt PF10321.9 KFO99783.1 - 0.0093 15.0 1.4 0.0093 15.0 1.4 3.0 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srt RAMP4 PF06624.12 KFO99783.1 - 0.012 15.6 0.2 0.7 10.0 0.0 2.7 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 7TM_GPCR_Srv PF10323.9 KFO99783.1 - 0.016 14.6 20.5 0.18 11.1 0.7 3.0 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF2207 PF09972.9 KFO99783.1 - 0.016 14.0 2.2 2.7 6.7 0.2 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) RIFIN PF02009.16 KFO99783.1 - 0.023 14.6 0.5 0.065 13.1 0.5 1.7 1 0 0 1 1 1 0 Rifin PemK_toxin PF02452.17 KFO99783.1 - 0.06 13.7 0.1 0.17 12.3 0.1 1.8 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system DUF3806 PF12713.7 KFO99783.1 - 0.09 12.6 1.4 3.3 7.6 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3806) CcmH PF03918.14 KFO99783.1 - 0.1 11.9 0.0 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Orf78 PF06024.12 KFO99783.1 - 0.18 12.1 6.0 4 7.8 0.6 3.7 3 1 0 3 3 3 0 Orf78 (ac78) Virul_fac_BrkB PF03631.15 KFO99783.1 - 1.8 8.1 14.6 0.038 13.6 0.9 3.0 3 0 0 3 3 3 0 Virulence factor BrkB zf-LITAF-like PF10601.9 KFO99783.1 - 6.5 7.1 10.0 1.7 9.0 1.1 3.6 3 1 0 3 3 3 0 LITAF-like zinc ribbon domain TPR_2 PF07719.17 KFO99784.1 - 1.3e-12 46.8 8.7 3.6e-05 23.5 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFO99784.1 - 3e-11 42.6 11.3 2.5e-05 23.9 1.8 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFO99784.1 - 5e-08 32.6 5.1 0.0016 18.5 0.2 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFO99784.1 - 0.00033 21.1 1.5 0.077 13.5 0.9 3.1 1 1 1 2 2 2 1 Tetratricopeptide repeat HEAT PF02985.22 KFO99784.1 - 0.0012 18.9 0.9 19 5.9 0.0 4.8 4 0 0 4 4 4 0 HEAT repeat ANAPC3 PF12895.7 KFO99784.1 - 0.0012 19.0 9.2 0.0042 17.3 7.3 2.9 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KFO99784.1 - 0.0015 18.8 7.9 0.0073 16.6 2.1 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFO99784.1 - 0.0023 17.9 4.1 0.31 11.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat HEAT_2 PF13646.6 KFO99784.1 - 0.0027 18.1 2.2 0.26 11.7 0.1 4.3 3 1 0 3 3 3 1 HEAT repeats Fis1_TPR_C PF14853.6 KFO99784.1 - 0.0084 16.2 7.8 0.14 12.3 0.1 3.7 3 1 1 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 KFO99784.1 - 0.01 16.4 1.4 0.17 12.6 0.1 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Cnd1 PF12717.7 KFO99784.1 - 0.014 15.4 0.4 3.9 7.5 0.0 3.8 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 TPR_14 PF13428.6 KFO99784.1 - 0.014 16.2 0.1 0.45 11.5 0.0 3.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Arm PF00514.23 KFO99784.1 - 0.019 15.0 10.0 5.9 7.1 0.1 5.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DUF3361 PF11841.8 KFO99784.1 - 0.021 14.7 2.6 0.97 9.4 0.0 3.8 2 2 2 4 4 4 0 Domain of unknown function (DUF3361) TPR_16 PF13432.6 KFO99784.1 - 0.036 14.7 0.0 2 9.2 0.0 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFO99784.1 - 0.069 13.3 0.1 0.31 11.2 0.0 2.1 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFO99784.1 - 0.075 12.7 4.8 2.8 7.7 1.2 3.2 1 1 2 3 3 3 0 TPR repeat TPR_17 PF13431.6 KFO99784.1 - 0.18 12.3 0.2 0.18 12.3 0.2 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat FliL PF03748.14 KFO99784.1 - 1.8 9.2 5.2 1.5 9.4 0.7 2.8 2 1 0 2 2 2 0 Flagellar basal body-associated protein FliL HEAT_EZ PF13513.6 KFO99784.1 - 4.1 8.0 8.7 19 5.9 0.0 5.0 5 1 2 7 7 7 0 HEAT-like repeat I-set PF07679.16 KFO99785.1 - 9.7e-78 256.3 5.7 7.6e-19 67.6 0.2 5.5 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO99785.1 - 5.5e-69 228.8 9.0 5.4e-16 59.0 0.1 6.1 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 KFO99785.1 - 1.8e-50 169.0 2.0 2.4e-10 40.5 0.0 5.5 5 0 0 5 5 5 5 Immunoglobulin domain Ig_2 PF13895.6 KFO99785.1 - 3.3e-43 145.9 2.3 2.2e-09 37.5 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin domain fn3 PF00041.21 KFO99785.1 - 5.5e-27 93.9 0.2 2.6e-14 53.3 0.1 3.1 2 0 0 2 2 2 2 Fibronectin type III domain V-set PF07686.17 KFO99785.1 - 2.3e-19 69.6 7.2 0.00012 22.2 0.0 7.5 5 4 0 5 5 5 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFO99785.1 - 1e-12 47.9 0.2 0.0056 16.7 0.0 5.2 5 0 0 5 5 5 3 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFO99785.1 - 1.1e-09 38.2 0.2 0.29 11.2 0.0 5.4 6 0 0 6 6 6 2 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 KFO99785.1 - 3.7e-09 36.7 3.2 1.5 9.1 0.2 6.7 5 3 0 5 5 5 2 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFO99785.1 - 1.3e-08 35.1 4.9 0.44 11.0 0.3 6.1 5 3 0 5 5 5 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 KFO99785.1 - 7.4e-08 32.7 4.1 0.0056 17.0 0.0 5.4 5 0 0 5 5 5 1 Immunoglobulin C1-set domain Ig_C17orf99 PF17736.1 KFO99785.1 - 1.3e-07 31.5 0.1 0.56 10.3 0.0 4.6 4 0 0 4 4 4 3 C17orf99 Ig domain Ig_6 PF18452.1 KFO99785.1 - 8.1e-06 25.3 0.0 3.2 7.4 0.0 4.8 5 0 0 5 5 5 1 Immunoglobulin domain Adeno_E3_CR1 PF02440.15 KFO99785.1 - 0.00012 21.8 1.3 0.32 10.8 0.0 3.9 4 0 0 4 4 4 1 Adenovirus E3 region protein CR1 Receptor_2B4 PF11465.8 KFO99785.1 - 0.0017 18.6 0.3 1.7 8.9 0.0 4.2 4 0 0 4 4 4 1 Natural killer cell receptor 2B4 Pur_ac_phosph_N PF16656.5 KFO99785.1 - 0.047 14.3 0.1 0.047 14.3 0.1 4.2 4 1 0 4 4 3 0 Purple acid Phosphatase, N-terminal domain Collagen_bind_2 PF12904.7 KFO99785.1 - 0.068 13.2 0.2 1.6 8.8 0.1 2.9 2 0 0 2 2 2 0 Putative collagen-binding domain of a collagenase SspH PF08141.12 KFO99785.1 - 0.12 12.5 0.1 27 5.0 0.0 2.9 3 0 0 3 3 2 0 Small acid-soluble spore protein H family PTPS PF01242.19 KFO99787.1 - 1.2e-32 112.5 0.0 1.4e-32 112.2 0.0 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase RPE65 PF03055.15 KFO99788.1 - 7.2e-129 431.0 0.1 8.7e-129 430.7 0.1 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF4964 PF16334.5 KFO99788.1 - 0.07 12.7 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) IL1 PF00340.19 KFO99789.1 - 2.6e-10 40.0 0.3 3.8e-10 39.5 0.3 1.2 1 0 0 1 1 1 1 Interleukin-1 / 18 QVR PF17064.5 KFO99789.1 - 0.091 13.0 1.9 0.13 12.5 0.4 1.9 1 1 1 2 2 2 0 Sleepless protein CybS PF05328.12 KFO99790.1 - 8.3e-24 83.8 0.0 1e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit ASFV_J13L PF05568.11 KFO99790.1 - 0.014 15.1 0.3 0.02 14.7 0.3 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF1658 PF07871.11 KFO99790.1 - 0.021 14.7 1.4 0.049 13.6 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) NKAP PF15692.5 KFO99791.1 - 1.4e-22 80.2 24.8 1.4e-22 80.2 24.8 5.0 2 1 3 5 5 5 1 NF-kappa-B-activating protein Macoilin PF09726.9 KFO99791.1 - 4 5.9 35.0 5.2 5.5 35.0 1.1 1 0 0 1 1 1 0 Macoilin family PIH1_CS PF18201.1 KFO99792.1 - 1.4e-12 47.8 0.1 2.8e-12 46.9 0.1 1.5 1 0 0 1 1 1 1 PIH1 CS-like domain PIH1 PF08190.12 KFO99792.1 - 8.6e-08 31.8 0.0 4.1e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 PIH1 N-terminal domain ArsA_HSP20 PF17886.1 KFO99792.1 - 0.00027 20.5 0.0 0.00059 19.4 0.0 1.5 1 0 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 KFO99792.1 - 0.0053 16.9 0.1 0.0091 16.1 0.1 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family 2-oxoacid_dh PF00198.23 KFO99793.1 - 2e-80 269.6 0.1 2.5e-80 269.3 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFO99793.1 - 4e-32 109.9 0.6 1.9e-15 56.5 0.0 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme E3_binding PF02817.17 KFO99793.1 - 1.9e-17 63.3 0.4 4.9e-17 62.0 0.4 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KFO99793.1 - 0.00014 21.6 0.0 1.1 9.1 0.0 3.0 2 0 0 2 2 2 2 Biotin-lipoyl like CCDC53 PF10152.9 KFO99793.1 - 0.89 10.0 3.2 5.8 7.3 0.5 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex HSP20 PF00011.21 KFO99794.1 - 4.5e-19 68.5 0.0 6.1e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Crystallin PF00525.18 KFO99794.1 - 1.9e-06 27.9 0.0 3.3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal HSP20 PF00011.21 KFO99795.1 - 6.5e-28 96.9 0.2 7.9e-28 96.6 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Crystallin PF00525.18 KFO99795.1 - 3.3e-21 75.2 1.0 5.4e-21 74.5 1.0 1.3 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal ArsA_HSP20 PF17886.1 KFO99795.1 - 0.0019 17.7 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF2431 PF10354.9 KFO99796.1 - 5.9e-44 150.3 0.0 1.2e-43 149.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) FDX-ACB PF03147.14 KFO99796.1 - 4.3e-16 59.1 0.0 1e-15 57.9 0.0 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2d PF01409.20 KFO99796.1 - 0.0025 17.4 0.0 0.0095 15.4 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) Glyco_transf_22 PF03901.17 KFO99797.1 - 2.8e-118 395.8 32.4 3.3e-118 395.5 32.4 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Pkinase PF00069.25 KFO99798.1 - 2.6e-68 230.2 0.0 5.1e-68 229.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO99798.1 - 1.8e-36 125.7 0.0 3.1e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFO99798.1 - 1.2e-08 34.7 0.0 2.6e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFO99798.1 - 5.1e-05 22.4 0.3 0.00018 20.6 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KFO99798.1 - 0.031 13.6 0.1 0.069 12.5 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BTG PF07742.12 KFO99799.1 - 9.9e-44 147.9 0.1 1.3e-43 147.5 0.1 1.2 1 0 0 1 1 1 1 BTG family PD-C2-AF1 PF09310.10 KFO99801.1 - 4.4e-129 429.2 13.9 5.1e-129 429.0 13.9 1.0 1 0 0 1 1 1 1 POU domain, class 2, associating factor 1 DUF5566 PF17721.1 KFO99802.1 - 1.3e-111 372.5 16.0 1.4e-111 372.4 16.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5566) ARL17 PF15840.5 KFO99802.1 - 0.045 14.1 0.8 0.21 12.0 0.8 2.2 1 1 0 1 1 1 0 ADP-ribosylation factor-like protein 17 zf-C2H2 PF00096.26 KFO99803.1 - 4.4e-18 64.7 77.9 6.5e-05 23.2 5.8 8.6 9 0 0 9 9 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO99803.1 - 6.6e-14 51.4 73.8 7.8e-05 23.2 2.3 8.9 9 0 0 9 9 8 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFO99803.1 - 2.2e-12 46.8 80.6 8.8e-06 25.9 3.3 9.7 11 0 0 11 11 10 6 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFO99803.1 - 6.8e-08 32.6 35.5 0.0075 16.5 0.5 6.3 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFO99803.1 - 0.0003 21.1 38.4 0.25 11.8 0.1 6.2 6 0 0 6 6 5 4 Zinc-finger of C2H2 type zf-Dof PF02701.15 KFO99803.1 - 0.00041 20.4 11.0 0.029 14.5 0.6 3.7 3 0 0 3 3 3 2 Dof domain, zinc finger zf-H2C2_5 PF13909.6 KFO99803.1 - 0.00043 20.0 5.7 0.00043 20.0 5.7 8.5 7 2 0 7 7 7 4 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFO99803.1 - 0.00062 19.7 13.0 0.0063 16.5 1.1 6.6 6 1 0 6 6 6 3 C2H2-type zinc finger zf-Di19 PF05605.12 KFO99803.1 - 0.0031 17.7 7.6 0.0031 17.7 7.6 5.1 3 1 1 5 5 5 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 KFO99803.1 - 0.02 14.8 0.7 0.02 14.8 0.7 5.0 6 0 0 6 6 6 0 zinc-finger of a C2HC-type SLIDE PF09111.10 KFO99803.1 - 0.077 13.0 0.0 0.57 10.2 0.0 2.1 2 0 0 2 2 2 0 SLIDE zf-C2H2_2 PF12756.7 KFO99803.1 - 5.8 7.3 40.3 0.17 12.2 4.3 5.8 2 1 4 7 7 7 0 C2H2 type zinc-finger (2 copies) NLRC4_HD2 PF17776.1 KFO99804.1 - 8.8e-08 32.7 0.0 0.0015 19.1 0.0 2.9 2 0 0 2 2 2 2 NLRC4 helical domain HD2 NACHT PF05729.12 KFO99804.1 - 1.8e-07 31.2 0.0 6.1e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 NACHT domain LRR_6 PF13516.6 KFO99804.1 - 2.2e-06 27.2 14.2 0.03 14.4 0.1 6.3 7 0 0 7 7 7 2 Leucine Rich repeat NOD2_WH PF17779.1 KFO99804.1 - 9.9e-06 25.8 1.4 0.00014 22.1 0.5 3.0 2 1 0 2 2 2 1 NOD2 winged helix domain STAS PF01740.21 KFO99804.1 - 0.0095 15.6 0.1 0.022 14.4 0.1 1.6 1 0 0 1 1 1 1 STAS domain LRR_1 PF00560.33 KFO99804.1 - 0.1 13.2 2.7 22 6.1 0.0 4.2 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_4 PF12799.7 KFO99804.1 - 4 8.0 12.0 1.4 9.4 0.0 4.3 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Lamprin PF06403.11 KFO99805.1 - 0.24 11.4 4.9 0.25 11.3 4.9 1.0 1 0 0 1 1 1 0 Lamprin TNF PF00229.18 KFO99807.1 - 7e-33 113.3 0.8 1.2e-32 112.6 0.8 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family DAGK_acc PF00609.19 KFO99809.1 - 1.1e-52 178.6 0.0 2.1e-52 177.7 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KFO99809.1 - 1.6e-26 92.4 0.0 5.8e-26 90.6 0.0 2.0 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 KFO99809.1 - 2.8e-19 68.7 25.4 6.8e-10 38.7 5.2 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) SAM_2 PF07647.17 KFO99809.1 - 4.1e-17 62.0 0.9 8.7e-17 61.0 0.2 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFO99809.1 - 3.6e-16 59.3 0.6 7.9e-16 58.3 0.6 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 KFO99809.1 - 4.7e-16 59.2 0.7 1e-15 58.1 0.7 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFO99809.1 - 0.00019 21.6 0.3 0.00041 20.6 0.3 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFO99809.1 - 0.00064 20.1 2.0 0.0065 16.9 2.0 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain C1_2 PF03107.16 KFO99809.1 - 0.0011 19.2 16.0 0.0054 17.0 5.7 2.6 2 0 0 2 2 2 2 C1 domain Mcp5_PH PF12814.7 KFO99809.1 - 0.077 13.1 1.3 0.089 12.9 0.1 1.8 2 0 0 2 2 1 0 Meiotic cell cortex C-terminal pleckstrin homology Cdh1_DBD_1 PF18196.1 KFO99809.1 - 0.094 13.0 5.0 0.32 11.3 5.0 1.9 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 TERB2 PF15101.6 KFO99809.1 - 5.2 7.1 6.1 12 5.9 6.1 1.6 1 0 0 1 1 1 0 Telomere-associated protein TERB2 V_ATPase_I PF01496.19 KFO99809.1 - 5.7 4.7 5.8 11 3.8 5.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RVT_1 PF00078.27 KFO99810.1 - 0.15 11.5 0.0 0.36 10.3 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_5 PF07728.14 KFO99812.1 - 6e-100 330.8 0.0 2.9e-39 134.2 0.0 3.6 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFO99812.1 - 1e-07 32.5 0.6 0.41 11.0 0.0 5.5 5 1 1 6 6 6 2 AAA ATPase domain AAA PF00004.29 KFO99812.1 - 1.4e-05 25.5 0.3 0.025 15.0 0.0 3.8 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 KFO99812.1 - 2.5e-05 24.1 0.0 0.0079 16.1 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KFO99812.1 - 8.2e-05 22.6 0.0 0.047 13.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFO99812.1 - 0.0001 22.6 0.2 0.5 10.6 0.0 4.2 4 1 0 4 4 3 1 AAA domain AAA_7 PF12775.7 KFO99812.1 - 0.00014 21.5 0.1 0.52 9.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region CbbQ_C PF08406.10 KFO99812.1 - 0.00014 22.0 0.0 0.65 10.3 0.0 2.7 2 0 0 2 2 2 2 CbbQ/NirQ/NorQ C-terminal TniB PF05621.11 KFO99812.1 - 0.00054 19.4 0.0 1.2 8.5 0.0 2.7 2 0 0 2 2 2 2 Bacterial TniB protein AAA_lid_7 PF17867.1 KFO99812.1 - 0.0015 18.7 0.1 0.023 14.9 0.1 2.7 3 0 0 3 3 2 1 Midasin AAA lid domain Mg_chelatase PF01078.21 KFO99812.1 - 0.0016 17.9 0.3 3.6 6.9 0.0 3.7 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 KFO99812.1 - 0.0037 17.4 0.0 0.86 9.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) TsaE PF02367.17 KFO99812.1 - 0.016 15.2 0.0 0.56 10.2 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 KFO99812.1 - 0.019 15.2 0.0 2.2 8.5 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 KFO99812.1 - 0.047 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFO99812.1 - 0.12 12.3 0.0 4 7.3 0.0 3.2 3 0 0 3 3 2 0 NACHT domain RNA_helicase PF00910.22 KFO99812.1 - 0.17 12.3 0.0 1.6 9.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NARP1 PF12569.8 KFO99813.1 - 1.2e-221 737.1 21.0 1.2e-221 737.1 21.0 1.8 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 KFO99813.1 - 2.3e-15 55.4 23.6 4.4e-05 23.3 0.1 8.4 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFO99813.1 - 9.6e-15 54.0 2.9 0.1 13.5 0.0 9.5 7 2 2 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFO99813.1 - 2.4e-12 46.0 24.8 0.00028 20.8 0.2 8.0 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFO99813.1 - 4e-10 39.2 9.2 8.3e-06 25.4 0.1 5.8 5 0 0 5 5 5 2 TPR repeat TPR_1 PF00515.28 KFO99813.1 - 1.4e-09 37.3 32.2 2e-05 24.2 0.6 8.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFO99813.1 - 1.4e-09 38.4 6.9 0.021 15.5 0.1 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFO99813.1 - 4.2e-08 33.6 11.4 0.041 14.4 0.3 5.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFO99813.1 - 5e-08 33.1 14.0 1.5 9.1 0.1 7.7 5 2 1 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO99813.1 - 9.1e-08 32.2 19.4 0.00023 21.3 0.5 6.4 6 1 1 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KFO99813.1 - 4.7e-06 26.0 1.4 4.7e-06 26.0 1.4 3.4 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFO99813.1 - 0.00044 20.1 13.0 0.071 13.2 0.1 7.1 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFO99813.1 - 0.00051 20.1 5.1 0.52 10.5 0.2 5.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFO99813.1 - 0.0044 16.9 8.8 31 4.6 0.1 6.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFO99813.1 - 0.018 15.6 0.0 1.3e+02 3.6 0.0 4.5 6 0 0 6 6 4 0 Tetratricopeptide repeat DUF789 PF05623.12 KFO99813.1 - 0.038 13.7 2.2 0.079 12.6 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF789) TPR_17 PF13431.6 KFO99813.1 - 0.07 13.5 15.8 1.1 9.8 0.0 7.2 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFO99813.1 - 0.43 11.3 13.0 32 5.4 0.1 6.1 7 1 0 7 7 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFO99813.1 - 2.5 8.2 24.3 9.4 6.4 0.2 6.9 7 0 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat PCRF PF03462.18 KFO99814.1 - 1.5e-49 168.5 0.5 1.5e-49 168.5 0.5 2.4 2 1 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KFO99814.1 - 5.8e-39 132.6 3.4 5.8e-39 132.6 3.4 2.0 3 0 0 3 3 3 1 RF-1 domain MIR PF02815.19 KFO99814.1 - 0.02 14.8 0.8 2.6 7.9 0.0 2.5 2 1 0 2 2 2 0 MIR domain HisKA PF00512.25 KFO99814.1 - 0.02 14.9 6.6 0.52 10.4 0.2 3.5 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain SPOB_a PF14689.6 KFO99814.1 - 0.17 11.6 2.5 2.9 7.7 0.0 3.0 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain CDI PF02234.19 KFO99814.1 - 0.48 10.7 4.1 0.52 10.6 0.0 3.0 3 0 0 3 3 3 0 Cyclin-dependent kinase inhibitor DUF4635 PF15466.6 KFO99814.1 - 8.4 5.9 10.9 16 5.0 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4635) WW PF00397.26 KFO99815.1 - 3e-20 72.0 18.6 6.6e-10 38.9 4.5 2.6 2 0 0 2 2 2 2 WW domain zf-U1 PF06220.12 KFO99815.1 - 3.2e-14 52.4 0.9 5.3e-14 51.7 0.9 1.4 1 0 0 1 1 1 1 U1 zinc finger Glyco_hyd_101C PF17451.2 KFO99815.1 - 0.00096 19.4 14.8 0.062 13.6 0.5 3.5 1 1 1 2 2 2 2 Glycosyl hydrolase 101 beta sandwich domain PQQ PF01011.21 KFO99815.1 - 0.058 13.3 0.2 2.9 8.0 0.0 2.6 2 0 0 2 2 2 0 PQQ enzyme repeat Elf-1_N PF12310.8 KFO99816.1 - 2.6e-36 124.5 1.0 7.8e-36 123.0 1.0 1.9 1 0 0 1 1 1 1 Transcription factor protein N terminal Ets PF00178.22 KFO99816.1 - 2e-34 117.9 1.0 3.3e-34 117.2 1.0 1.3 1 0 0 1 1 1 1 Ets-domain SGS PF05002.15 KFO99817.1 - 1.3e-33 114.9 2.3 1.3e-33 114.9 2.3 2.0 2 0 0 2 2 2 1 SGS domain CS PF04969.16 KFO99817.1 - 1.7e-17 64.2 2.3 2.2e-17 63.8 1.3 1.8 2 0 0 2 2 1 1 CS domain TPR_2 PF07719.17 KFO99817.1 - 3.9e-09 35.9 10.8 6.5e-06 25.9 3.7 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFO99817.1 - 4.5e-09 35.7 11.6 2.8e-06 26.9 4.9 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFO99817.1 - 1.9e-07 31.0 4.8 0.00058 20.1 0.9 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFO99817.1 - 1.2e-05 25.1 5.5 0.00015 21.7 2.8 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFO99817.1 - 3.7e-05 23.3 8.5 0.0046 16.6 0.8 3.2 1 1 2 3 3 3 2 TPR repeat TPR_14 PF13428.6 KFO99817.1 - 0.00093 19.8 1.5 0.032 15.0 0.5 2.8 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 KFO99817.1 - 0.0074 16.6 2.0 0.027 14.8 0.4 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFO99817.1 - 0.022 15.1 3.1 0.12 12.7 3.5 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFO99817.1 - 0.028 15.0 2.9 0.11 13.2 0.7 2.3 1 1 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFO99817.1 - 0.035 14.3 2.9 0.069 13.4 2.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF2018 PF09442.10 KFO99817.1 - 0.1 13.6 0.1 0.27 12.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2018) TPR_19 PF14559.6 KFO99817.1 - 0.31 11.6 4.8 1.2 9.7 3.4 2.4 1 1 2 3 3 3 0 Tetratricopeptide repeat BRICHOS PF04089.14 KFO99818.1 - 1.3e-21 76.7 0.0 2.4e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 BRICHOS domain Cadherin PF00028.17 KFO99819.1 - 2.3e-63 210.6 0.4 4.7e-15 55.8 0.0 5.3 4 1 1 5 5 5 5 Cadherin domain TMEM154 PF15102.6 KFO99819.1 - 0.022 14.7 0.1 0.045 13.7 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family Protocadherin PF08374.11 KFO99819.1 - 0.1 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Protocadherin EphA2_TM PF14575.6 KFO99819.1 - 0.17 12.8 0.0 0.36 11.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain OLF PF02191.16 KFO99820.1 - 2.1e-80 269.9 9.5 2.1e-80 269.9 9.5 1.5 2 0 0 2 2 2 1 Olfactomedin-like domain CENP-F_leu_zip PF10473.9 KFO99820.1 - 0.22 11.5 3.0 0.41 10.7 3.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tubulin-binding PF00418.19 KFO99821.1 - 5.5e-28 96.7 15.3 1.1e-15 57.3 2.7 2.0 2 0 0 2 2 2 2 Tau and MAP protein, tubulin-binding repeat Yae1_N PF09811.9 KFO99822.1 - 2.4e-12 46.3 56.5 1.8e+04 -27.7 56.5 6.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Cadherin PF00028.17 KFO99824.1 - 1.1e-92 304.7 0.0 7.5e-18 64.8 0.0 6.5 6 0 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.12 KFO99824.1 - 6.7e-17 61.1 0.1 1e-09 38.1 0.0 5.0 5 0 0 5 5 5 2 Cadherin-like Cadherin_4 PF17803.1 KFO99824.1 - 1.8e-05 25.3 6.6 0.17 12.5 0.0 4.9 4 0 0 4 4 4 2 Bacterial cadherin-like domain Cadherin_C_2 PF16492.5 KFO99824.1 - 2.2e-05 25.1 0.0 8.1e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal RMI1_N PF08585.12 KFO99826.1 - 4.5e-27 95.2 8.0 2.4e-22 79.8 0.0 3.5 2 2 1 3 3 3 2 RecQ mediated genome instability protein SMN PF06003.12 KFO99826.1 - 9.8e-11 41.4 0.0 9.8e-11 41.4 0.0 2.5 2 1 0 2 2 2 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 KFO99826.1 - 1.3e-09 38.1 0.0 2.7e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Tudor domain UBA PF00627.31 KFO99826.1 - 7.2e-07 29.0 0.1 1.5e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Cadherin PF00028.17 KFO99827.1 - 1.5e-89 294.6 0.0 1.4e-19 70.3 0.0 7.2 7 0 0 7 7 7 6 Cadherin domain Cadherin_2 PF08266.12 KFO99827.1 - 2.5e-13 49.6 0.0 0.00033 20.4 0.0 6.2 6 1 0 6 6 6 3 Cadherin-like RET_CLD1 PF17756.1 KFO99827.1 - 0.00045 20.5 0.0 11 6.3 0.0 4.1 4 0 0 4 4 4 2 RET Cadherin like domain 1 DUF4958 PF16319.5 KFO99827.1 - 0.026 12.5 0.0 0.11 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4958) Cadherin_4 PF17803.1 KFO99827.1 - 0.033 14.8 11.3 2.6 8.7 0.3 4.7 5 0 0 5 5 5 0 Bacterial cadherin-like domain VASt PF16016.5 KFO99829.1 - 2.1e-37 128.9 2.0 3.3e-37 128.3 2.0 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KFO99829.1 - 2.2e-28 98.4 0.1 4e-28 97.6 0.1 1.5 1 0 0 1 1 1 1 GRAM domain V-set PF07686.17 KFO99830.1 - 4.5e-20 71.9 0.1 5.7e-20 71.5 0.1 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFO99830.1 - 0.00031 20.9 0.4 0.00065 19.8 0.4 1.6 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFO99830.1 - 0.00066 19.7 0.2 0.0016 18.5 0.2 1.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO99830.1 - 0.00084 19.9 0.2 0.0018 18.9 0.2 1.5 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFO99830.1 - 0.0034 17.7 0.3 0.011 16.1 0.3 1.9 1 1 0 1 1 1 1 Immunoglobulin domain EII-GUT PF03608.13 KFO99830.1 - 0.028 14.3 0.1 0.09 12.7 0.0 1.7 2 0 0 2 2 2 0 PTS system enzyme II sorbitol-specific factor Herpes_gE PF02480.16 KFO99830.1 - 0.028 13.2 0.2 0.41 9.3 0.1 2.0 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Ig_6 PF18452.1 KFO99830.1 - 0.029 13.9 0.0 0.083 12.5 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin domain Ac76 PF05814.11 KFO99830.1 - 0.06 13.4 0.2 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Orf76 (Ac76) E1-E2_ATPase PF00122.20 KFO99831.1 - 8e-45 152.6 1.1 8e-45 152.6 1.1 3.3 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFO99831.1 - 9.9e-43 146.0 1.3 9.9e-43 146.0 1.3 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KFO99831.1 - 1.3e-26 92.5 0.0 2.8e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFO99831.1 - 5.4e-20 72.6 0.0 1.1e-10 42.2 0.0 2.7 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFO99831.1 - 4e-16 58.5 0.0 8.1e-16 57.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFO99831.1 - 1e-06 28.7 2.2 0.0004 20.2 1.2 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFO99831.1 - 0.027 14.9 0.1 0.19 12.1 0.1 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Sigma70_r4 PF04545.16 KFO99831.1 - 0.21 11.2 0.0 0.59 9.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 AKAP_110 PF05716.13 KFO99833.1 - 5.3e-08 31.6 0.7 1e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 A-kinase anchor protein 110 kDa (AKAP 110) SmAKAP PF15127.6 KFO99833.1 - 5.4e-05 24.3 8.5 9.9 7.4 0.0 6.6 5 1 0 5 5 5 3 Small membrane A-kinase anchor protein Symplekin_C PF12295.8 KFO99833.1 - 0.35 10.9 1.6 2.5 8.2 0.1 2.4 2 0 0 2 2 2 0 Symplekin tight junction protein C terminal WD40 PF00400.32 KFO99834.1 - 9.2e-67 219.4 19.9 8.6e-08 32.7 0.0 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO99834.1 - 1.2e-19 70.4 0.8 0.0089 16.3 0.0 7.3 1 1 7 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFO99834.1 - 3.3e-09 36.5 2.6 0.16 11.2 0.1 5.5 2 2 2 5 5 5 4 WD40-like domain Nup160 PF11715.8 KFO99834.1 - 2.6e-06 26.4 1.2 1.1 7.9 0.0 5.2 4 1 2 6 6 6 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFO99834.1 - 0.0011 18.0 5.7 0.27 10.2 0.1 4.7 1 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_3 PF15911.5 KFO99834.1 - 0.013 15.5 0.5 23 5.1 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat CEP19 PF14933.6 KFO99834.1 - 0.077 13.3 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 CEP19-like protein DUF5642 PF18702.1 KFO99834.1 - 0.08 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5642) ZirS_C PF16583.5 KFO99834.1 - 0.08 12.5 0.0 2.6 7.6 0.0 2.9 2 1 1 3 3 3 0 Zinc-regulated secreted antivirulence protein C-terminal domain Frtz PF11768.8 KFO99834.1 - 0.16 10.3 0.0 1.9 6.7 0.0 2.7 2 1 2 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz IL8 PF00048.20 KFO99835.1 - 1.2e-18 66.9 0.1 1.4e-18 66.7 0.1 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like MF_alpha_N PF05436.11 KFO99835.1 - 0.096 12.6 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Folate_carrier PF01770.18 KFO99836.1 - 3.4e-148 493.8 15.9 3.4e-91 306.0 0.2 2.0 1 1 1 2 2 2 2 Reduced folate carrier MFS_1 PF07690.16 KFO99836.1 - 1.1e-05 24.5 3.0 1.1e-05 24.5 3.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ArfGap PF01412.18 KFO99837.1 - 6e-11 42.5 0.0 1.2e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf dsrm PF00035.26 KFO99838.1 - 0.0066 17.1 0.0 0.013 16.2 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif MmcB-like PF06319.12 KFO99838.1 - 0.025 14.3 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 DNA repair protein MmcB-like Ribonucleas_3_3 PF14622.6 KFO99838.1 - 0.082 13.1 0.0 0.15 12.2 0.0 1.5 1 1 0 1 1 1 0 Ribonuclease-III-like Miff PF05644.11 KFO99839.1 - 8.6e-72 242.2 0.1 9.3e-72 242.1 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial and peroxisomal fission factor Mff Collagen PF01391.18 KFO99840.1 - 2.3e-186 603.8 690.2 5.4e-10 38.9 19.0 27.0 9 7 16 25 25 25 25 Collagen triple helix repeat (20 copies) C4 PF01413.19 KFO99840.1 - 3.4e-80 265.7 3.4 2.5e-42 143.7 0.6 2.1 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Collagen PF01391.18 KFO99841.1 - 3e-180 584.2 695.0 4.5e-10 39.1 22.1 28.1 7 6 18 25 25 25 24 Collagen triple helix repeat (20 copies) C4 PF01413.19 KFO99841.1 - 5.3e-79 261.8 2.1 4e-43 146.3 0.4 2.1 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Rhomboid PF01694.22 KFO99842.1 - 2.2e-18 66.7 6.2 3.7e-18 65.9 6.2 1.4 1 0 0 1 1 1 1 Rhomboid family COPI_assoc PF08507.10 KFO99842.1 - 2.3 8.3 9.1 0.15 12.1 1.3 2.6 3 0 0 3 3 3 0 COPI associated protein IRS PF02174.17 KFO99843.1 - 3.9e-31 106.9 0.0 6.2e-31 106.3 0.0 1.3 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.29 KFO99843.1 - 1.7e-10 41.3 0.1 3.5e-10 40.3 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFO99843.1 - 5.5e-05 23.5 0.1 0.0001 22.7 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain NYAP_N PF15439.6 KFO99844.1 - 7.6e-103 344.8 42.5 8.1e-92 308.5 22.5 5.0 4 2 2 6 6 6 3 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter NYAP_C PF15452.6 KFO99844.1 - 5.3e-41 141.2 13.6 5.3e-41 141.2 13.6 1.9 2 0 0 2 2 2 1 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Guanylate_cyc PF00211.20 KFO99845.1 - 5.1e-69 231.6 0.2 7.7e-69 231.0 0.2 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOB PF07700.15 KFO99845.1 - 1.4e-46 158.4 0.6 3.4e-46 157.2 0.6 1.7 1 1 0 1 1 1 1 Haem-NO-binding HNOBA PF07701.14 KFO99845.1 - 5.7e-33 114.2 12.0 2.2e-19 69.8 6.0 2.3 2 0 0 2 2 2 2 Heme NO binding associated Cullin PF00888.22 KFO99846.1 - 1.3e-227 757.4 9.8 1.5e-227 757.1 9.8 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KFO99846.1 - 1.7e-27 95.2 1.1 1.7e-27 95.2 1.1 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain Phage_antitermQ PF06530.12 KFO99846.1 - 0.0087 16.0 0.2 0.05 13.5 0.1 2.4 2 0 0 2 2 2 1 Phage antitermination protein Q RhgB_N PF09284.10 KFO99846.1 - 0.047 13.2 0.1 0.093 12.2 0.1 1.4 1 0 0 1 1 1 0 Rhamnogalacturonan lyase B, N-terminal Phage_TAC_12 PF12363.8 KFO99846.1 - 0.055 13.9 0.8 1.1 9.7 0.0 3.3 3 0 0 3 3 3 0 Phage tail assembly chaperone protein, TAC RuvB_C PF05491.13 KFO99846.1 - 0.83 9.6 2.7 1e+02 2.9 0.0 4.4 4 0 0 4 4 4 0 RuvB C-terminal winged helix domain Glyco_hydro_4C PF11975.8 KFO99846.1 - 1.6 8.8 8.8 1.8 8.6 1.6 3.6 3 1 0 3 3 3 0 Family 4 glycosyl hydrolase C-terminal domain WAC_Acf1_DNA_bd PF10537.9 KFO99846.1 - 2.4 8.7 7.1 0.93 10.1 0.3 3.4 3 0 0 3 3 3 0 ATP-utilising chromatin assembly and remodelling N-terminal FAM124 PF15067.6 KFO99847.1 - 4.5e-102 340.7 0.2 5e-102 340.5 0.2 1.0 1 0 0 1 1 1 1 FAM124 family Serpin PF00079.20 KFO99848.1 - 6.9e-104 348.1 0.1 7.7e-104 347.9 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) WD40 PF00400.32 KFO99849.1 - 1.1e-16 60.9 15.5 1.4e-05 25.8 0.7 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat FYVE PF01363.21 KFO99849.1 - 2.8e-14 53.0 7.6 2.8e-14 53.0 7.6 1.7 2 0 0 2 2 2 1 FYVE zinc finger ANAPC4_WD40 PF12894.7 KFO99849.1 - 4.1e-06 27.0 0.2 0.069 13.5 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain ELYS-bb PF16687.5 KFO99849.1 - 0.02 13.5 0.0 0.033 12.8 0.0 1.2 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin IBR PF01485.21 KFO99849.1 - 1.2 9.4 12.2 5 7.4 0.6 2.8 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain FYVE_2 PF02318.16 KFO99849.1 - 1.6 9.0 8.3 4.6 7.5 8.3 1.8 1 1 0 1 1 1 0 FYVE-type zinc finger zf-B_box PF00643.24 KFO99849.1 - 5.8 7.2 14.0 0.12 12.6 1.7 3.7 4 0 0 4 4 4 0 B-box zinc finger Yae1_N PF09811.9 KFO99851.1 - 9.6e-18 63.6 49.2 0.06 13.1 17.9 5.6 1 1 1 2 2 2 1 Essential protein Yae1, N terminal Vinculin PF01044.19 KFO99852.1 - 0 1062.3 41.0 1.1e-219 732.3 24.4 2.1 1 1 1 2 2 2 2 Vinculin family CorA PF01544.18 KFO99852.1 - 0.79 9.0 6.0 0.6 9.4 0.2 3.1 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein Rotamase PF00639.21 KFO99852.1 - 0.84 10.6 12.6 4 8.5 0.1 5.7 7 0 0 7 7 7 0 PPIC-type PPIASE domain SAWADEE PF16719.5 KFO99852.1 - 6.1 6.9 8.5 0.57 10.2 0.1 3.4 4 1 1 5 5 5 0 SAWADEE domain LRR_8 PF13855.6 KFO99853.1 - 3.3e-51 170.9 20.6 1.6e-16 59.8 1.1 5.4 2 1 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KFO99853.1 - 4.5e-22 77.8 16.9 7e-06 26.3 0.5 6.4 5 1 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFO99853.1 - 5.5e-20 71.6 0.0 1.1e-09 38.3 0.0 2.8 1 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFO99853.1 - 1.1e-13 51.0 2.0 0.00011 21.8 0.0 3.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFO99853.1 - 5.3e-11 41.5 17.5 0.59 10.9 0.2 9.9 9 1 0 9 9 9 2 Leucine Rich Repeat LRR_6 PF13516.6 KFO99853.1 - 5.3e-08 32.3 18.4 2 8.7 0.0 8.5 10 0 0 10 10 9 3 Leucine Rich repeat LRRNT PF01462.18 KFO99853.1 - 0.00084 18.9 1.5 0.00084 18.9 1.5 2.7 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_12 PF18837.1 KFO99853.1 - 0.0041 16.7 1.4 0.23 11.2 0.0 3.4 4 0 0 4 4 4 1 Leucine-rich repeat HemY_N PF07219.13 KFO99853.1 - 0.016 15.4 0.3 0.027 14.6 0.3 1.4 1 0 0 1 1 1 0 HemY protein N-terminus UL97 PF06734.12 KFO99853.1 - 0.019 14.9 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 UL97 Pyrid_oxidase_2 PF13883.6 KFO99853.1 - 0.073 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DUF4519 PF15012.6 KFO99853.1 - 5.1 7.3 5.3 1.4 9.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Yae1_N PF09811.9 KFO99854.1 - 5.4e-19 67.6 58.1 0.0028 17.3 5.7 6.1 1 1 1 2 2 2 1 Essential protein Yae1, N terminal MmgE_PrpD PF03972.14 KFO99855.1 - 4.4e-124 414.4 0.0 5.3e-124 414.1 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF4971 PF16341.5 KFO99855.1 - 0.058 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4971) DJ-1_PfpI PF01965.24 KFO99856.1 - 1e-05 25.4 0.3 2.8e-05 24.0 0.3 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family GATase_5 PF13507.6 KFO99856.1 - 0.023 13.8 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain CLN5 PF15014.6 KFO99857.1 - 1.3e-165 550.4 3.6 1.5e-165 550.2 3.6 1.0 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 Lipase3_N PF03893.16 KFO99857.1 - 0.045 13.8 0.3 0.21 11.6 0.1 2.1 2 0 0 2 2 2 0 Lipase 3 N-terminal region F-box PF00646.33 KFO99858.1 - 1.5e-08 34.3 2.8 1.7e-08 34.1 0.2 2.5 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KFO99858.1 - 2.6e-08 33.6 1.4 2.6e-08 33.6 1.4 2.4 3 0 0 3 3 3 1 F-box-like DUF4116 PF13475.6 KFO99858.1 - 0.0085 15.8 0.3 0.029 14.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4116) F-box_5 PF18511.1 KFO99858.1 - 0.017 14.6 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 F-box SPRY PF00622.28 KFO99859.1 - 2.8e-19 69.4 0.0 4.4e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.16 KFO99859.1 - 8.6e-10 38.8 3.4 1.7e-09 37.8 3.4 1.5 1 0 0 1 1 1 1 SOCS box HELP PF03451.14 KFO99859.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 HELP motif Cadherin PF00028.17 KFO99860.1 - 1.2e-15 57.7 0.2 4.8e-10 39.7 0.5 2.7 2 0 0 2 2 2 2 Cadherin domain Laminin_G_3 PF13385.6 KFO99860.1 - 0.00011 22.3 0.0 0.00019 21.6 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily V_ATPase_I PF01496.19 KFO99860.1 - 0.00053 18.1 2.5 0.00087 17.4 2.5 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family SpoIIIAH PF12685.7 KFO99860.1 - 0.0028 17.5 4.2 0.0048 16.7 4.2 1.3 1 0 0 1 1 1 1 SpoIIIAH-like protein TMEM132D_C PF15706.5 KFO99860.1 - 0.014 15.1 0.0 0.044 13.6 0.0 1.8 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Chordopox_A13L PF05961.11 KFO99860.1 - 0.026 14.7 0.0 0.088 13.1 0.0 1.9 1 0 0 1 1 1 0 Chordopoxvirus A13L protein SID-1_RNA_chan PF13965.6 KFO99860.1 - 0.039 12.4 1.2 0.059 11.8 1.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Myc_N PF01056.18 KFO99860.1 - 0.084 12.8 7.6 0.13 12.1 7.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region TMEM51 PF15345.6 KFO99860.1 - 0.69 9.7 3.7 1.7 8.4 3.7 1.6 1 1 0 1 1 1 0 Transmembrane protein 51 Zip PF02535.22 KFO99860.1 - 1.2 8.3 4.0 1.8 7.7 4.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NOA36 PF06524.12 KFO99860.1 - 1.4 8.1 12.1 2.4 7.4 12.1 1.3 1 0 0 1 1 1 0 NOA36 protein LRR19-TM PF15176.6 KFO99860.1 - 3.3 7.8 9.0 13 5.8 9.0 2.0 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain CTP_transf_like PF01467.26 KFO99861.1 - 5.6e-35 120.6 0.0 2.2e-34 118.7 0.0 1.8 1 1 0 1 1 1 1 Cytidylyltransferase-like Lipocalin PF00061.23 KFO99862.1 - 7.9e-18 65.0 0.3 8.6e-18 64.9 0.3 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 KFO99862.1 - 2.3e-05 24.3 0.2 2.9e-05 24.0 0.2 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.23 KFO99863.1 - 1.5e-17 64.2 6.0 1.6e-17 64.0 6.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 KFO99863.1 - 2.6e-06 27.4 0.5 3e-06 27.2 0.5 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Coatomer_WDAD PF04053.14 KFO99864.1 - 1.3e-170 568.3 0.0 2.2e-170 567.5 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 KFO99864.1 - 3.4e-41 138.5 8.1 1.3e-09 38.5 0.1 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFO99864.1 - 4.8e-07 30.0 0.5 0.63 10.4 0.1 6.2 4 3 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain MetallophosC PF16370.5 KFO99864.1 - 0.049 13.9 0.1 0.6 10.3 0.0 2.5 2 1 1 3 3 3 0 C terminal of Calcineurin-like phosphoesterase MRP-S22 PF10245.9 KFO99865.1 - 1.4e-104 349.2 3.8 1.4e-104 349.2 3.8 1.5 2 0 0 2 2 2 1 Mitochondrial 28S ribosomal protein S22 Forkhead PF00250.18 KFO99866.1 - 4.6e-39 132.6 0.0 7.2e-39 131.9 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain PI3Ka PF00613.20 KFO99867.1 - 3.3e-62 209.2 1.2 7.5e-62 208.0 1.2 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KFO99867.1 - 5.4e-60 203.3 0.0 1.2e-59 202.1 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_p85B PF02192.16 KFO99867.1 - 3.4e-33 113.2 0.1 1.2e-32 111.4 0.1 2.1 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain PI3K_rbd PF00794.18 KFO99867.1 - 3.7e-31 107.4 0.1 8.9e-31 106.2 0.1 1.7 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 KFO99867.1 - 1.6e-19 70.2 0.0 3.1e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 RWD PF05773.22 KFO99867.1 - 0.0024 18.1 0.8 0.77 10.1 0.1 3.0 3 0 0 3 3 3 2 RWD domain DUF4135 PF13575.6 KFO99867.1 - 0.034 13.5 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Synaptobrevin PF00957.21 KFO99869.1 - 1.4e-21 76.1 1.0 1.5e-21 76.0 1.0 1.0 1 0 0 1 1 1 1 Synaptobrevin Seryl_tRNA_N PF02403.22 KFO99869.1 - 0.029 14.6 0.2 0.033 14.4 0.2 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Period_C PF12114.8 KFO99870.1 - 1.4e-93 312.0 5.9 1.4e-93 312.0 5.9 4.1 4 1 0 4 4 4 1 Period protein 2/3C-terminal region PAS_3 PF08447.12 KFO99870.1 - 1e-12 48.1 0.0 9.6e-12 45.0 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 KFO99870.1 - 5.5e-09 36.2 0.0 3.6e-08 33.5 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KFO99870.1 - 2.5e-07 30.7 0.0 0.00024 21.1 0.0 3.0 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 KFO99871.1 - 4.9e-16 58.4 2.2 1.1e-15 57.3 2.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 KFO99871.1 - 3e-11 43.4 0.1 6.1e-11 42.3 0.1 1.6 1 0 0 1 1 1 1 Hairy Orange Mo25 PF08569.11 KFO99872.1 - 1e-142 475.3 16.6 1.2e-142 475.2 16.6 1.0 1 0 0 1 1 1 1 Mo25-like BRICHOS PF04089.14 KFO99873.1 - 1.2e-21 76.7 0.0 1.8e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 BRICHOS domain 7tm_1 PF00001.21 KFO99874.1 - 3.2e-34 118.4 19.0 3.8e-34 118.2 19.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-C2HC_2 PF13913.6 KFO99875.1 - 4.5e-19 67.9 10.1 4.2e-11 42.5 0.9 2.8 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 KFO99875.1 - 0.001 19.7 5.6 0.68 10.9 0.3 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFO99875.1 - 0.0016 18.8 3.4 0.19 12.2 0.1 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type c-SKI_SMAD_bind PF08782.10 KFO99875.1 - 0.0038 17.4 0.8 0.01 16.0 0.0 1.9 1 1 1 2 2 2 1 c-SKI Smad4 binding domain zinc_ribbon_4 PF13717.6 KFO99875.1 - 0.014 15.3 0.1 4.4 7.3 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DUF2318 PF10080.9 KFO99875.1 - 0.022 14.9 0.6 0.82 9.8 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Rad50_zn_hook PF04423.14 KFO99875.1 - 0.035 14.0 0.2 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 Rad50 zinc hook motif Sgf11 PF08209.11 KFO99875.1 - 0.041 13.4 0.8 1.4 8.6 0.1 2.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) ADK_lid PF05191.14 KFO99875.1 - 0.046 13.7 0.5 9 6.4 0.0 2.8 2 1 0 2 2 2 0 Adenylate kinase, active site lid Vps36-NZF-N PF16988.5 KFO99875.1 - 0.11 11.9 1.8 0.61 9.5 0.1 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF2256 PF10013.9 KFO99875.1 - 0.12 12.5 1.1 8.9 6.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-CCHC PF00098.23 KFO99875.1 - 0.13 12.4 4.5 3.5 7.9 0.5 2.6 2 0 0 2 2 2 0 Zinc knuckle zf_C2H2_13 PF18508.1 KFO99875.1 - 0.24 11.0 3.3 2.2 7.9 0.4 2.3 2 0 0 2 2 2 0 Zinc finger domain zf-C2HC_2 PF13913.6 KFO99876.1 - 9e-23 79.7 4.8 8.8e-12 44.6 0.5 2.7 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 KFO99876.1 - 0.00012 22.6 3.8 0.11 13.4 0.2 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFO99876.1 - 0.003 17.9 2.5 0.16 12.5 0.0 3.0 3 0 0 3 3 3 1 Zinc finger, C2H2 type c-SKI_SMAD_bind PF08782.10 KFO99876.1 - 0.017 15.3 0.1 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 c-SKI Smad4 binding domain Sgf11 PF08209.11 KFO99876.1 - 0.062 12.9 1.2 4.4 7.0 0.1 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C2H2_6 PF13912.6 KFO99876.1 - 0.063 13.3 0.2 3.9 7.6 0.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.15 KFO99876.1 - 0.17 11.9 1.5 9.2 6.4 0.1 2.5 3 0 0 3 3 3 0 BED zinc finger SNCAIP_SNCA_bd PF16700.5 KFO99877.1 - 3.9e-24 84.1 8.6 1.2e-23 82.5 8.6 1.9 1 0 0 1 1 1 1 Synphilin-1 alpha-Synuclein-binding domain Ank_2 PF12796.7 KFO99877.1 - 6.9e-23 81.0 4.3 1.1e-10 41.9 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFO99877.1 - 1.7e-15 57.1 0.4 9.9e-07 29.2 0.0 3.5 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFO99877.1 - 2.5e-12 46.7 0.2 0.0011 19.2 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KFO99877.1 - 2.1e-06 27.9 2.3 0.0011 19.4 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KFO99877.1 - 7.1e-06 26.0 0.5 0.19 12.4 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Vps5 PF09325.10 KFO99878.1 - 2.7e-84 282.4 18.9 2.7e-84 282.4 18.9 1.4 2 0 0 2 2 1 1 Vps5 C terminal like PX PF00787.24 KFO99878.1 - 4.2e-30 104.0 0.3 8e-29 99.9 0.1 2.4 2 0 0 2 2 2 1 PX domain Sorting_nexin PF03700.13 KFO99878.1 - 1.6e-16 61.0 2.6 4.3e-16 59.7 2.6 1.8 1 0 0 1 1 1 1 Sorting nexin, N-terminal domain Spc7 PF08317.11 KFO99878.1 - 0.0018 17.2 16.5 0.046 12.6 3.5 2.4 2 0 0 2 2 2 2 Spc7 kinetochore protein BAR_3_WASP_bdg PF10456.9 KFO99878.1 - 0.028 13.9 7.4 0.85 9.0 7.4 2.5 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein DUF5113 PF17140.4 KFO99878.1 - 0.045 13.6 0.4 0.1 12.4 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) SpoU_methylase PF00588.19 KFO99878.1 - 0.18 12.0 0.3 0.46 10.6 0.3 1.7 1 0 0 1 1 1 0 SpoU rRNA Methylase family DUF3138 PF11336.8 KFO99878.1 - 0.18 10.3 4.0 0.3 9.7 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF241 PF03087.14 KFO99878.1 - 0.31 10.8 11.0 0.15 11.9 3.2 2.7 1 1 1 2 2 2 0 Arabidopsis protein of unknown function BLOC1_2 PF10046.9 KFO99878.1 - 0.47 10.8 14.4 0.28 11.5 1.1 3.7 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3775 PF12616.8 KFO99878.1 - 0.51 10.4 2.9 0.59 10.2 0.0 2.6 3 0 0 3 3 1 0 Protein of unknown function (DUF3775) DUF4618 PF15397.6 KFO99878.1 - 0.76 9.2 14.1 0.39 10.1 1.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) DUF2203 PF09969.9 KFO99878.1 - 1.4 9.6 10.1 4.8 7.9 1.6 3.0 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Csm2_III-A PF03750.13 KFO99878.1 - 1.4 9.7 8.9 1.1 10.1 1.8 3.1 2 1 1 3 3 3 0 Csm2 Type III-A Seryl_tRNA_N PF02403.22 KFO99878.1 - 1.7 8.9 14.9 4.9 7.4 3.9 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Exonuc_VII_L PF02601.15 KFO99878.1 - 2.8 7.4 18.9 0.6 9.6 6.5 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit DHR10 PF18595.1 KFO99878.1 - 3.1 7.9 20.4 1.6 8.8 4.4 3.3 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain Tropomyosin PF00261.20 KFO99878.1 - 3.6 6.9 17.2 0.056 12.8 4.3 2.4 2 0 0 2 2 2 0 Tropomyosin Phage_HK97_TLTM PF06120.11 KFO99878.1 - 4.6 6.3 12.9 6.5 5.9 3.2 2.2 2 0 0 2 2 2 0 Tail length tape measure protein Sec34 PF04136.15 KFO99878.1 - 6 6.7 13.4 1.1 9.1 1.6 3.1 2 1 1 3 3 3 0 Sec34-like family Allexi_40kDa PF05549.11 KFO99878.1 - 6.4 6.2 8.4 0.85 9.1 0.8 2.6 2 1 1 3 3 3 0 Allexivirus 40kDa protein IATP PF04568.12 KFO99878.1 - 7.3 7.1 11.8 0.89 10.0 0.2 3.2 2 1 1 3 3 3 0 Mitochondrial ATPase inhibitor, IATP FlaC_arch PF05377.11 KFO99878.1 - 7.7 7.0 7.2 47 4.5 0.2 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) HR1 PF02185.16 KFO99878.1 - 7.8 6.7 14.3 0.94 9.6 0.8 3.4 3 0 0 3 3 3 0 Hr1 repeat GrpE PF01025.19 KFO99878.1 - 9.6 5.8 17.9 0.27 10.9 6.1 2.6 2 1 0 2 2 2 0 GrpE PX PF00787.24 KFO99879.1 - 1.2e-13 51.0 3.3 3.8e-13 49.4 2.6 1.8 1 1 1 2 2 2 2 PX domain DUF99 PF01949.16 KFO99879.1 - 0.13 11.6 0.1 0.18 11.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF99 Pro_isomerase PF00160.21 KFO99880.1 - 2.3e-47 161.2 0.1 2.6e-47 161.0 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-C2H2 PF00096.26 KFO99881.1 - 3.9e-13 49.0 20.0 2.1e-05 24.7 0.1 4.4 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFO99881.1 - 2.1e-10 40.5 17.4 0.00014 22.4 1.5 4.6 5 0 0 5 5 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFO99881.1 - 3.2e-10 40.0 14.7 0.0017 18.7 0.2 4.8 4 0 0 4 4 4 3 Zinc-finger double domain SET PF00856.28 KFO99881.1 - 2.3e-07 31.3 0.1 9.4e-06 26.1 0.1 2.3 1 1 0 1 1 1 1 SET domain zf-C2H2_jaz PF12171.8 KFO99881.1 - 0.00042 20.5 0.3 0.043 14.1 0.0 3.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KFO99881.1 - 0.029 14.8 5.4 2.6 8.6 0.0 3.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 KFO99881.1 - 0.038 13.8 1.1 0.038 13.8 1.1 3.9 4 0 0 4 4 4 0 C2H2-type zinc-finger domain UPF0113_N PF17833.1 KFO99881.1 - 0.16 12.6 0.0 0.59 10.7 0.0 1.9 2 0 0 2 2 2 0 UPF0113 Pre-PUA domain DUF629 PF04780.12 KFO99881.1 - 0.31 9.5 11.2 1.9 6.9 2.9 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF629) zf-C2HC_2 PF13913.6 KFO99881.1 - 0.45 10.5 0.0 0.45 10.5 0.0 3.7 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KFO99881.1 - 0.46 10.3 11.0 0.64 9.8 0.1 3.8 3 0 0 3 3 3 0 zinc-finger C2H2-type PyrI_C PF02748.15 KFO99881.1 - 0.48 10.4 3.0 3.7 7.5 0.0 3.0 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-LYAR PF08790.11 KFO99881.1 - 0.91 9.5 5.9 11 6.0 0.3 3.7 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 KFO99881.1 - 3.1 8.2 8.0 25 5.3 0.0 3.7 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) Zn_ribbon_SprT PF17283.2 KFO99881.1 - 3.3 7.7 12.4 0.88 9.5 1.9 4.0 4 0 0 4 4 4 0 SprT-like zinc ribbon domain zf-CHCC PF10276.9 KFO99881.1 - 3.5 7.7 7.2 0.7 10.0 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger domain zf-BED PF02892.15 KFO99881.1 - 4.8 7.3 10.3 5.6 7.1 0.3 3.7 3 1 1 4 4 3 0 BED zinc finger zf-Di19 PF05605.12 KFO99881.1 - 6.8 7.1 13.6 3.8 7.9 0.0 4.0 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF3668 PF12416.8 KFO99882.1 - 6e-90 301.0 0.0 6e-90 301.0 0.0 2.9 3 0 0 3 3 3 1 Cep120 protein C2 PF00168.30 KFO99882.1 - 3.4e-08 33.7 0.0 0.1 12.9 0.0 3.5 3 0 0 3 3 3 3 C2 domain CK1gamma_C PF12605.8 KFO99883.1 - 4.9e-30 104.6 3.9 9.1e-30 103.8 3.9 1.4 1 0 0 1 1 1 1 Casein kinase 1 gamma C terminal Pkinase PF00069.25 KFO99883.1 - 1.3e-26 93.5 0.0 1.7e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO99883.1 - 8.4e-15 54.7 0.0 1.1e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFO99883.1 - 4.5e-08 32.3 0.1 4.5e-08 32.3 0.1 1.4 2 0 0 2 2 2 1 Fungal protein kinase PIP49_C PF12260.8 KFO99883.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 FAM27 PF15832.5 KFO99885.1 - 1 9.9 11.1 0.76 10.4 4.1 3.4 3 0 0 3 3 3 0 FAM27 D and E protein family CysA_C_terminal PF17850.1 KFO99886.1 - 0.59 10.8 3.6 34 5.1 0.6 3.1 1 1 0 2 2 2 0 CysA C-terminal regulatory domain RVT_1 PF00078.27 KFO99888.1 - 0.0003 20.4 0.0 0.00047 19.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GRAM PF02893.20 KFO99889.1 - 3.2e-18 65.6 0.2 7e-18 64.6 0.2 1.5 1 0 0 1 1 1 1 GRAM domain Plasmodium_Vir PF05795.11 KFO99889.1 - 0.0095 15.4 0.2 0.016 14.6 0.2 1.3 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Aldedh PF00171.22 KFO99890.1 - 9.8e-126 419.9 0.0 1.1e-125 419.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.6 KFO99890.1 - 0.066 13.2 0.4 0.21 11.7 0.2 1.8 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated DUF1211 PF06736.11 KFO99891.1 - 2.7e-34 117.4 4.0 2.9e-22 78.9 0.0 3.7 4 1 0 4 4 4 2 Protein of unknown function (DUF1211) PDEase_I PF00233.19 KFO99892.1 - 4.7e-79 265.5 3.9 4.7e-79 265.5 3.9 1.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 KFO99892.1 - 1e-29 103.9 0.0 6.2e-14 52.8 0.0 2.7 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.6 KFO99892.1 - 6e-10 39.6 0.0 0.00038 20.8 0.0 2.4 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 KFO99892.1 - 1.6e-07 31.8 0.0 0.00054 20.3 0.0 2.7 2 1 0 2 2 2 2 GAF domain SpoVT_C PF15714.5 KFO99892.1 - 3.7e-05 23.8 0.1 0.028 14.5 0.0 3.4 3 0 0 3 3 3 1 Stage V sporulation protein T C-terminal, transcription factor Cut12 PF11500.8 KFO99892.1 - 0.0011 18.9 0.3 0.0027 17.6 0.3 1.6 1 0 0 1 1 1 1 Spindle pole body formation-associated protein Lipocalin PF00061.23 KFO99893.1 - 1.1e-17 64.5 0.0 1.4e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.12 KFO99893.1 - 5.2e-10 39.4 0.0 7.9e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Lipocalin-like domain Triabin PF03973.13 KFO99893.1 - 9.9e-06 25.5 0.1 0.001 19.0 0.0 2.2 2 0 0 2 2 2 2 Triabin Glyco_hydro_39 PF01229.17 KFO99894.1 - 8.2e-149 496.3 0.1 1e-148 496.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Sulfate_transp PF00916.20 KFO99895.1 - 1.4e-120 402.6 25.1 1.9e-120 402.1 25.1 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFO99895.1 - 4.8e-26 90.7 0.0 9.2e-26 89.8 0.0 1.5 1 0 0 1 1 1 1 STAS domain Neur_chan_LBD PF02931.23 KFO99896.1 - 1e-76 257.1 2.7 1.3e-76 256.8 2.7 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFO99896.1 - 3.5e-62 210.6 9.8 4.4e-62 210.2 9.8 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF1286 PF06939.11 KFO99896.1 - 0.076 13.3 6.8 0.065 13.5 3.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1286) Neur_chan_LBD PF02931.23 KFO99897.1 - 5.4e-74 248.3 0.1 8.7e-74 247.6 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFO99897.1 - 1.3e-64 218.6 14.9 1.7e-49 169.0 10.2 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region PepSY_TM PF03929.16 KFO99897.1 - 0.59 9.8 4.6 0.12 12.1 1.1 1.6 2 0 0 2 2 2 0 PepSY-associated TM region THAP PF05485.12 KFO99898.1 - 6.2e-12 46.3 1.1 6.2e-12 46.3 1.1 2.0 2 1 0 2 2 2 1 THAP domain Cep57_CLD PF14073.6 KFO99898.1 - 2.9e-05 24.2 2.7 4.4e-05 23.6 2.7 1.2 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 PI3K_P85_iSH2 PF16454.5 KFO99898.1 - 0.0013 18.4 7.1 0.0019 17.8 7.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ADIP PF11559.8 KFO99898.1 - 0.0032 17.6 9.6 0.0047 17.0 9.6 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Macoilin PF09726.9 KFO99898.1 - 0.0053 15.4 3.5 0.0073 14.9 3.5 1.1 1 0 0 1 1 1 1 Macoilin family GrpE PF01025.19 KFO99898.1 - 0.0059 16.3 4.2 0.009 15.7 4.2 1.2 1 0 0 1 1 1 1 GrpE Ax_dynein_light PF10211.9 KFO99898.1 - 0.0068 16.4 6.2 0.012 15.5 6.2 1.3 1 0 0 1 1 1 1 Axonemal dynein light chain Tropomyosin PF00261.20 KFO99898.1 - 0.015 14.7 5.7 0.021 14.2 5.7 1.2 1 0 0 1 1 1 0 Tropomyosin DUF16 PF01519.16 KFO99898.1 - 0.017 15.6 4.2 0.033 14.7 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 MPS2 PF17060.5 KFO99898.1 - 0.017 14.4 2.0 0.023 14.0 2.0 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF4391 PF14335.6 KFO99898.1 - 0.019 14.7 2.9 0.029 14.1 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) Tropomyosin_1 PF12718.7 KFO99898.1 - 0.02 15.1 4.5 0.032 14.4 4.5 1.3 1 0 0 1 1 1 0 Tropomyosin like DUF573 PF04504.14 KFO99898.1 - 0.028 15.0 1.2 0.067 13.9 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF573 DUF4140 PF13600.6 KFO99898.1 - 0.075 13.5 0.6 0.11 12.9 0.6 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Sec2p PF06428.11 KFO99898.1 - 0.09 12.8 4.2 0.14 12.2 4.2 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p ATG16 PF08614.11 KFO99898.1 - 0.13 12.5 7.0 0.17 12.1 7.0 1.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 KFO99898.1 - 0.15 11.3 1.0 0.2 11.0 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 KFO99898.1 - 0.21 12.0 3.4 0.32 11.4 3.4 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 KFO99898.1 - 0.22 11.3 7.8 0.38 10.6 7.8 1.4 1 0 0 1 1 1 0 Septum formation initiator YPEB PF14620.6 KFO99898.1 - 0.22 10.8 2.9 0.32 10.3 2.9 1.1 1 0 0 1 1 1 0 YpeB sporulation FliD_C PF07195.12 KFO99898.1 - 0.36 10.2 1.4 0.5 9.7 1.4 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Spc7 PF08317.11 KFO99898.1 - 0.69 8.7 7.7 0.97 8.2 7.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ABC_tran_Xtn PF12848.7 KFO99898.1 - 0.78 9.8 9.4 1.4 9.0 9.4 1.4 1 0 0 1 1 1 0 ABC transporter 4HBT_3 PF13622.6 KFO99898.1 - 2 8.6 4.4 2.8 8.1 4.4 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily XhlA PF10779.9 KFO99898.1 - 2.7 8.2 4.4 4.2 7.6 4.4 1.2 1 0 0 1 1 1 0 Haemolysin XhlA USP8_interact PF08941.10 KFO99898.1 - 2.9 7.7 6.2 5.1 6.9 6.2 1.4 1 0 0 1 1 1 0 USP8 interacting zf-RING_UBOX PF13445.6 KFO99899.1 - 1.9e-09 37.4 5.0 3.9e-09 36.4 2.4 2.2 1 1 1 2 2 2 1 RING-type zinc-finger DUF1232 PF06803.12 KFO99899.1 - 2.2e-09 37.0 9.4 2.2e-09 37.0 9.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1232) zf-C3HC4 PF00097.25 KFO99899.1 - 8.7e-09 35.1 3.8 1.4e-08 34.4 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFO99899.1 - 1.6e-08 34.2 2.8 2.3e-08 33.7 2.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFO99899.1 - 3.3e-08 33.5 4.9 7.9e-08 32.3 5.0 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KFO99899.1 - 7.9e-07 28.8 4.7 1.9e-06 27.6 4.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFO99899.1 - 9e-07 29.1 6.5 1.4e-06 28.5 6.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFO99899.1 - 9.4e-06 25.5 4.7 1.8e-05 24.6 4.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFO99899.1 - 2.7e-05 23.9 4.4 8.6e-05 22.3 4.5 1.8 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KFO99899.1 - 0.0042 16.9 1.3 0.0074 16.1 1.3 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Cys_rich_CPXG PF14255.6 KFO99899.1 - 0.014 15.3 0.8 6 6.9 0.0 2.4 2 0 0 2 2 2 0 Cysteine-rich CPXCG zf-ANAPC11 PF12861.7 KFO99899.1 - 0.041 13.9 2.2 0.075 13.1 2.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DpnI_C PF17726.1 KFO99899.1 - 0.05 13.7 0.1 0.093 12.9 0.1 1.4 1 0 0 1 1 1 0 Dam-replacing HTH domain AvrLm4-7 PF18661.1 KFO99899.1 - 0.16 13.0 0.8 0.29 12.2 0.8 1.3 1 0 0 1 1 1 0 Avirulence Effector AvrLm4-7 zf-RING_10 PF16685.5 KFO99899.1 - 0.29 11.3 2.4 0.55 10.4 2.4 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 TerY_C PF15616.6 KFO99899.1 - 1.1 9.4 5.0 3.6 7.7 5.0 1.7 1 1 0 1 1 1 0 TerY-C metal binding domain zf-rbx1 PF12678.7 KFO99899.1 - 1.2 9.4 7.4 3.1 8.2 7.4 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-WRNIP1_ubi PF18279.1 KFO99899.1 - 3.7 8.4 5.8 29 5.6 0.2 2.6 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain HOOK PF05622.12 KFO99900.1 - 0 1037.0 82.5 0 1036.8 82.5 1.0 1 0 0 1 1 1 1 HOOK protein HALZ PF02183.18 KFO99900.1 - 0.0016 18.7 3.2 0.0016 18.7 3.2 8.3 9 1 1 10 10 10 2 Homeobox associated leucine zipper Mod_r PF07200.13 KFO99900.1 - 0.002 18.2 19.3 0.002 18.2 19.3 6.6 2 2 4 6 6 6 3 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.11 KFO99900.1 - 0.0041 16.0 23.6 0.0041 16.0 23.6 5.1 2 2 3 5 5 5 3 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KFO99900.1 - 0.49 10.5 104.3 0.15 12.1 23.1 6.9 3 2 3 6 6 6 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 KFO99900.1 - 3 8.2 91.5 1.5 9.3 12.1 4.8 1 1 3 4 4 4 0 Fez1 NPV_P10 PF05531.12 KFO99900.1 - 8 7.0 42.4 2.5 8.6 0.2 8.5 5 3 0 5 5 5 0 Nucleopolyhedrovirus P10 protein zf-Di19 PF05605.12 KFO99901.1 - 7.5e-22 77.4 1.4 7.5e-22 77.4 1.4 1.9 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding ZZ PF00569.17 KFO99901.1 - 1.1e-09 37.9 6.2 1.1e-09 37.9 6.2 2.6 3 0 0 3 3 3 1 Zinc finger, ZZ type TagA PF12561.8 KFO99901.1 - 0.0006 20.2 0.1 0.0013 19.1 0.1 1.5 1 0 0 1 1 1 1 ToxR activated gene A lipoprotein domain zf-C2H2 PF00096.26 KFO99901.1 - 0.0095 16.4 0.3 0.0095 16.4 0.3 3.2 4 1 0 4 4 1 1 Zinc finger, C2H2 type Dicty_REP PF05086.12 KFO99901.1 - 0.034 12.2 4.0 0.044 11.8 4.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zinc_ribbon_9 PF14369.6 KFO99901.1 - 0.11 12.8 1.8 12 6.3 0.1 2.9 2 0 0 2 2 2 0 zinc-ribbon TFIIA PF03153.13 KFO99901.1 - 0.22 11.5 7.8 0.28 11.1 7.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C2H2_4 PF13894.6 KFO99901.1 - 0.46 11.5 0.2 0.46 11.5 0.2 3.7 4 0 0 4 4 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO99901.1 - 0.47 10.8 0.1 0.47 10.8 0.1 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Di19_C PF14571.6 KFO99901.1 - 0.83 10.2 9.3 4.4 7.9 9.3 2.2 1 1 0 1 1 1 0 Stress-induced protein Di19, C-terminal zf-ribbon_3 PF13248.6 KFO99901.1 - 2.4 7.7 8.8 3.4 7.2 0.3 2.9 3 0 0 3 3 3 0 zinc-ribbon domain FOXP-CC PF16159.5 KFO99901.1 - 2.7 8.7 6.2 36 5.1 0.4 3.5 4 0 0 4 4 4 0 FOXP coiled-coil domain PPTA PF01239.22 KFO99902.1 - 8e-48 158.9 17.4 2.4e-11 43.0 0.4 5.7 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF4219 PF13961.6 KFO99902.1 - 0.11 12.2 11.4 2.8 7.7 0.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) PS_Dcarbxylase PF02666.15 KFO99902.1 - 0.18 11.3 0.1 0.24 10.9 0.1 1.2 1 0 0 1 1 1 0 Phosphatidylserine decarboxylase TPR_14 PF13428.6 KFO99902.1 - 0.22 12.5 1.4 9.2 7.4 0.4 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat Glyco_transf_10 PF00852.19 KFO99903.1 - 9.7e-38 129.6 0.1 2e-37 128.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 KFO99903.1 - 5.3e-11 43.0 0.1 1.5e-10 41.5 0.1 1.7 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Neuregulin PF02158.15 KFO99904.1 - 2.5e-155 517.3 36.2 3.4e-155 516.9 36.2 1.2 1 0 0 1 1 1 1 Neuregulin intracellular region I-set PF07679.16 KFO99904.1 - 8.1e-15 54.7 0.7 3.8e-14 52.5 0.1 2.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFO99904.1 - 3.4e-12 46.8 1.5 8.9e-12 45.5 0.1 2.5 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 KFO99904.1 - 3.4e-10 39.9 1.7 5e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFO99904.1 - 9.1e-09 35.5 0.4 3.9e-08 33.5 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFO99904.1 - 1.9e-06 28.0 0.4 1.9e-05 24.8 0.1 2.7 2 1 0 2 2 2 1 Immunoglobulin V-set domain C1-set PF07654.15 KFO99904.1 - 0.00015 22.0 1.3 0.00044 20.6 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin C1-set domain EGF PF00008.27 KFO99904.1 - 0.0016 18.7 3.8 0.0035 17.6 3.8 1.6 1 0 0 1 1 1 1 EGF-like domain C2-set_2 PF08205.12 KFO99904.1 - 0.0016 18.4 1.9 0.012 15.6 0.0 2.8 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain DUF973 PF06157.11 KFO99904.1 - 0.061 12.4 0.1 0.13 11.3 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF973) Cyt_b-c1_8 PF10890.8 KFO99904.1 - 0.087 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 TMEM132D_C PF15706.5 KFO99904.1 - 0.15 11.8 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term EGF_2 PF07974.13 KFO99904.1 - 0.7 10.3 2.7 2 8.8 2.7 1.8 1 1 0 1 1 1 0 EGF-like domain Thioredoxin PF00085.20 KFO99905.1 - 3.9e-83 274.1 0.1 4.9e-30 103.6 0.0 3.0 3 0 0 3 3 3 3 Thioredoxin OST3_OST6 PF04756.13 KFO99905.1 - 4.6e-13 49.2 0.1 0.0023 17.3 0.0 3.1 3 0 0 3 3 3 3 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KFO99905.1 - 1.2e-12 48.2 0.9 0.0043 17.5 0.0 3.6 3 1 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFO99905.1 - 6.1e-09 36.1 0.4 0.61 10.4 0.0 5.2 3 3 1 4 4 4 3 Thioredoxin-like Thioredoxin_6 PF13848.6 KFO99905.1 - 1.6e-07 31.4 0.0 0.061 13.2 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like domain HyaE PF07449.11 KFO99905.1 - 3.5e-07 30.1 0.0 0.007 16.3 0.0 3.1 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE TraF PF13728.6 KFO99905.1 - 1.1e-05 25.4 6.5 0.16 11.8 0.0 4.1 3 2 2 5 5 5 3 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 KFO99905.1 - 0.00049 20.2 2.1 7.2 6.9 0.1 3.6 3 0 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.21 KFO99905.1 - 0.0017 18.3 1.8 1.4 8.8 0.0 2.9 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_9 PF14595.6 KFO99905.1 - 0.0061 16.3 0.1 3.7 7.3 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Mu-like_Com PF10122.9 KFO99905.1 - 1.2 8.6 5.3 5 6.7 0.9 3.1 3 0 0 3 3 3 0 Mu-like prophage protein Com Ribosomal_L40e PF01020.17 KFO99905.1 - 1.3 8.9 3.9 67 3.5 0.5 3.5 3 0 0 3 3 3 0 Ribosomal L40e family TGFb_propeptide PF00688.18 KFO99906.1 - 1.9e-61 207.9 0.0 2.8e-61 207.4 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 KFO99906.1 - 8.7e-39 132.7 0.9 2.1e-38 131.5 0.9 1.7 1 0 0 1 1 1 1 Transforming growth factor beta like domain Plectin PF00681.20 KFO99907.1 - 5.1e-126 410.3 9.8 1.9e-16 59.6 0.1 14.4 12 2 2 14 14 14 11 Plectin repeat Spectrin_like PF18373.1 KFO99907.1 - 7e-32 109.3 2.3 7e-32 109.3 2.3 6.1 7 0 0 7 7 7 1 Spectrin like domain SH3_10 PF17902.1 KFO99907.1 - 3.5e-19 68.6 0.0 1.4e-18 66.7 0.0 2.1 1 0 0 1 1 1 1 SH3 domain SOGA PF11365.8 KFO99907.1 - 0.002 19.2 8.0 0.002 19.2 8.0 14.1 6 1 10 17 17 17 2 Protein SOGA RIO1 PF01163.22 KFO99908.1 - 6.4e-76 254.1 0.5 6.4e-76 254.1 0.5 1.9 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KFO99908.1 - 0.0045 17.0 0.0 0.034 14.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family TRAP_alpha PF03896.16 KFO99909.1 - 7.8e-110 366.6 1.8 9.1e-110 366.3 1.8 1.0 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit E1_DerP2_DerF2 PF02221.15 KFO99911.1 - 5.4e-09 36.6 0.4 6.8e-09 36.3 0.4 1.2 1 0 0 1 1 1 1 ML domain DUF3324 PF11797.8 KFO99911.1 - 0.077 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminal (DUF3324) Transglut_C PF00927.22 KFO99912.1 - 1.6e-38 131.1 0.3 5.8e-21 74.6 0.1 2.5 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_N PF00868.20 KFO99912.1 - 2.1e-36 124.8 0.1 1e-34 119.4 0.0 2.8 3 0 0 3 3 3 1 Transglutaminase family Transglut_core PF01841.19 KFO99912.1 - 2.3e-16 60.2 0.2 5.4e-16 59.0 0.2 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily TUG-UBL1 PF11470.8 KFO99912.1 - 0.13 12.5 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 TUG ubiquitin-like domain CAMSAP_CC1 PF17095.5 KFO99913.1 - 0.068 13.0 0.8 0.12 12.3 0.6 1.5 1 1 1 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin NRN1 PF15056.6 KFO99914.1 - 2.2e-23 82.2 0.5 2.6e-23 81.9 0.5 1.1 1 0 0 1 1 1 1 Neuritin protein family tRNA-synt_2d PF01409.20 KFO99915.1 - 2.5e-48 164.7 2.0 2.5e-30 105.7 0.2 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KFO99915.1 - 1.7e-21 76.4 0.0 7.7e-21 74.3 0.0 2.2 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.20 KFO99915.1 - 0.016 14.3 0.0 2.1 7.4 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) Complex1_LYR PF05347.15 KFO99916.1 - 9.5e-12 44.8 1.9 1e-11 44.7 1.9 1.0 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFO99916.1 - 0.00024 21.8 0.6 0.00027 21.6 0.6 1.0 1 0 0 1 1 1 1 Complex1_LYR-like Ribonuc_P_40 PF08584.11 KFO99917.1 - 4.2e-94 315.0 0.0 4.8e-94 314.8 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit ECH_1 PF00378.20 KFO99918.1 - 1.7e-32 112.7 0.0 2.4e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Chromo PF00385.24 KFO99918.1 - 1.8e-18 66.2 3.7 4.4e-18 64.9 3.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ECH_2 PF16113.5 KFO99918.1 - 1.9e-16 60.5 1.0 9.7e-16 58.2 0.0 2.0 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Mtf2_C PF14061.6 KFO99918.1 - 0.012 15.8 0.2 0.023 14.9 0.2 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Tudor-knot PF11717.8 KFO99918.1 - 5.3 7.0 8.5 0.28 11.1 0.8 2.7 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain ECH_1 PF00378.20 KFO99919.1 - 5e-42 143.9 0.0 7.4e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ACBP PF00887.19 KFO99919.1 - 6e-30 103.3 0.5 1.2e-29 102.3 0.5 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein ECH_2 PF16113.5 KFO99919.1 - 7.4e-19 68.4 0.0 2.3e-18 66.8 0.0 1.7 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase LamB_YcsF PF03746.16 KFO99919.1 - 0.051 13.2 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 LamB/YcsF family TPR_21 PF09976.9 KFO99919.1 - 0.07 12.8 2.2 1.7 8.3 0.6 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain Pkinase PF00069.25 KFO99920.1 - 1.2e-49 169.0 0.8 1.2e-49 169.0 0.8 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO99920.1 - 8.9e-23 80.9 0.1 2.7e-22 79.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KFO99920.1 - 0.0012 18.0 0.3 0.002 17.2 0.3 1.4 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Sugar_tr PF00083.24 KFO99921.1 - 1.7e-23 83.3 19.6 2.4e-23 82.7 19.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFO99921.1 - 1.4e-17 63.7 20.6 6.2e-14 51.7 25.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PAC4 PF16093.5 KFO99922.1 - 0.0058 16.8 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Tubulin PF00091.25 KFO99923.1 - 1.3e-31 110.4 0.0 1.6e-31 110.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.9 KFO99923.1 - 7.1e-07 29.5 0.0 1.1e-06 28.9 0.0 1.6 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 KFO99925.1 - 4e-59 200.1 0.0 6.5e-59 199.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFO99925.1 - 8.6e-44 148.7 0.1 1.4e-43 148.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 KFO99925.1 - 0.017 14.3 0.0 0.036 13.2 0.0 1.5 1 0 0 1 1 1 0 Tubulin like Tubulin_3 PF14881.6 KFO99925.1 - 0.019 14.7 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Abhydrolase_1 PF00561.20 KFO99927.1 - 1.2e-25 90.6 0.0 2.3e-16 60.2 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFO99927.1 - 4.2e-15 55.7 0.0 3e-08 33.2 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFO99927.1 - 5.9e-13 49.9 0.0 8.9e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KFO99927.1 - 0.00038 20.1 0.0 0.022 14.3 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.13 KFO99927.1 - 0.00052 19.7 0.2 0.0033 17.1 0.0 2.3 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 KFO99927.1 - 0.00057 20.0 0.0 0.0012 18.9 0.0 1.5 2 0 0 2 2 2 1 TAP-like protein Peptidase_S9 PF00326.21 KFO99927.1 - 0.0011 18.5 0.3 0.019 14.5 0.3 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 KFO99927.1 - 0.0084 16.0 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 KFO99927.1 - 0.015 15.1 0.1 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.20 KFO99927.1 - 0.052 13.2 0.3 0.26 10.9 0.1 2.1 2 1 1 3 3 3 0 Putative esterase Pkinase_Tyr PF07714.17 KFO99928.1 - 1.4e-51 175.3 0.0 2e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFO99928.1 - 6.7e-51 173.2 0.0 1.1e-50 172.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Death PF00531.22 KFO99928.1 - 7.5e-21 74.1 0.9 1.3e-19 70.1 0.2 2.6 2 0 0 2 2 2 1 Death domain RHIM PF12721.7 KFO99928.1 - 4.5e-08 33.5 1.5 4.5e-08 33.5 1.5 2.5 2 1 0 2 2 2 1 RIP homotypic interaction motif RIO1 PF01163.22 KFO99928.1 - 0.0023 17.5 0.1 0.0041 16.7 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KFO99928.1 - 0.0084 15.5 0.0 0.026 13.8 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFO99928.1 - 0.063 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFO99928.1 - 0.12 12.3 0.0 0.36 10.7 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFO99928.1 - 0.13 11.2 0.0 0.13 11.2 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Flavodoxin_2 PF02525.17 KFO99929.1 - 1.9e-51 174.6 0.0 2.2e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 KFO99929.1 - 1e-11 44.9 0.0 1.8e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.7 KFO99929.1 - 0.004 16.9 0.0 0.0058 16.4 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin DSPc PF00782.20 KFO99930.1 - 1.4e-26 92.9 0.5 7.4e-25 87.3 0.1 2.3 1 1 1 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFO99930.1 - 0.0012 18.5 0.3 0.0012 18.5 0.3 1.9 1 1 1 2 2 2 1 Protein-tyrosine phosphatase Complex1_LYR PF05347.15 KFO99930.1 - 0.0059 16.6 1.2 0.018 15.1 1.2 1.9 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Helo_like_N PF17111.5 KFO99930.1 - 0.014 14.7 0.1 0.023 14.1 0.1 1.2 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins IRF-3 PF10401.9 KFO99931.1 - 5e-63 212.1 0.2 6.6e-63 211.7 0.2 1.1 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.17 KFO99931.1 - 1.9e-42 143.8 0.2 2.9e-42 143.2 0.2 1.3 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor MH2 PF03166.14 KFO99931.1 - 0.00077 19.7 0.0 0.0012 19.2 0.0 1.2 1 0 0 1 1 1 1 MH2 domain Sec5 PF15469.6 KFO99932.1 - 7.5e-55 185.7 2.0 1.2e-54 185.1 0.1 2.4 3 0 0 3 3 3 1 Exocyst complex component Sec5 TIG PF01833.24 KFO99932.1 - 1.7e-08 34.4 0.6 3.4e-08 33.5 0.6 1.5 1 0 0 1 1 1 1 IPT/TIG domain SAM_2 PF07647.17 KFO99932.1 - 0.005 16.9 0.1 0.026 14.6 0.1 2.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4618 PF15397.6 KFO99932.1 - 0.75 9.2 6.3 8.5 5.7 1.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) GDP_Man_Dehyd PF16363.5 KFO99933.1 - 1.3e-157 524.4 0.0 1.5e-157 524.2 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFO99933.1 - 7.7e-69 231.8 0.0 1e-68 231.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFO99933.1 - 0.00046 19.4 0.0 0.00061 19.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain MgsA_C PF12002.8 KFO99934.1 - 1e-58 198.0 0.0 3.4e-58 196.3 0.0 1.8 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KFO99934.1 - 1.9e-25 89.0 0.0 4.3e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KFO99934.1 - 2.7e-09 37.5 0.4 5.2e-09 36.6 0.4 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFO99934.1 - 5.5e-05 23.0 0.1 0.00015 21.5 0.1 1.7 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 KFO99934.1 - 0.0045 16.7 0.0 0.016 14.9 0.0 1.8 1 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 KFO99934.1 - 0.02 14.9 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta2 PF13177.6 KFO99934.1 - 0.072 12.9 0.2 0.14 11.9 0.2 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit ResIII PF04851.15 KFO99934.1 - 0.1 12.6 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Serpin PF00079.20 KFO99935.1 - 1.3e-132 442.6 3.6 1.4e-132 442.5 3.6 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFO99936.1 - 1.3e-40 139.9 1.6 1.4e-40 139.7 1.6 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFO99937.1 - 6.3e-115 384.4 3.4 7.1e-115 384.3 3.4 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFO99938.1 - 1.3e-130 436.0 9.9 1.5e-130 435.8 9.9 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) WcbI PF18588.1 KFO99938.1 - 0.088 12.4 0.0 0.72 9.4 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis enzyme WcbI Serpin PF00079.20 KFO99939.1 - 7.4e-129 430.3 10.0 8.3e-129 430.1 10.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFO99940.1 - 2.3e-127 425.4 2.7 2.6e-127 425.2 2.7 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFO99941.1 - 1.4e-75 254.9 0.0 1.6e-75 254.8 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) EF1_GNE PF00736.19 KFO99941.1 - 0.039 14.1 0.3 0.078 13.2 0.3 1.8 1 1 0 1 1 1 0 EF-1 guanine nucleotide exchange domain DUF3161 PF11362.8 KFO99941.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) Serpin PF00079.20 KFO99942.1 - 4.4e-76 256.6 0.2 4.9e-76 256.5 0.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Sec-ASP3 PF15432.6 KFO99942.1 - 0.039 14.1 0.1 0.098 12.8 0.0 1.6 2 0 0 2 2 2 0 Accessory Sec secretory system ASP3 Serpin PF00079.20 KFO99943.1 - 1.8e-125 419.1 1.9 2e-125 419.0 1.9 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFO99944.1 - 6e-100 335.1 7.7 6.7e-100 335.0 7.7 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Toprim_Crpt PF13342.6 KFO99944.1 - 0.077 13.0 2.0 0.65 10.0 0.2 3.1 3 0 0 3 3 3 0 C-terminal repeat of topoisomerase AAA PF00004.29 KFO99945.1 - 2.4e-31 108.9 0.0 2.9e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KFO99945.1 - 2.2e-06 27.1 0.0 2.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KFO99945.1 - 2.3e-06 27.5 0.0 3e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KFO99945.1 - 2.5e-06 27.8 0.1 0.0021 18.3 0.0 2.1 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 KFO99945.1 - 2.6e-06 28.0 0.0 0.00073 20.0 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KFO99945.1 - 1e-05 25.3 0.0 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KFO99945.1 - 1.4e-05 25.1 0.0 2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFO99945.1 - 1.7e-05 24.8 0.0 4e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KFO99945.1 - 6.6e-05 23.5 0.0 0.00011 22.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KFO99945.1 - 9.9e-05 22.0 0.1 0.32 10.5 0.1 2.1 1 1 0 2 2 2 2 AAA domain DUF815 PF05673.13 KFO99945.1 - 0.00015 21.1 0.0 0.00018 20.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 KFO99945.1 - 0.00024 21.3 0.0 0.00037 20.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KFO99945.1 - 0.00091 19.4 0.0 0.0013 18.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 KFO99945.1 - 0.0016 17.8 0.1 0.78 9.0 0.0 2.1 1 1 1 2 2 2 2 KaiC AAA_24 PF13479.6 KFO99945.1 - 0.0018 18.0 0.0 0.003 17.3 0.0 1.3 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KFO99945.1 - 0.0025 18.2 0.0 0.0036 17.7 0.0 1.3 1 1 0 1 1 1 1 RNA helicase NACHT PF05729.12 KFO99945.1 - 0.0027 17.6 0.0 0.068 13.1 0.0 2.1 1 1 1 2 2 2 1 NACHT domain TniB PF05621.11 KFO99945.1 - 0.0031 16.9 0.0 1.4 8.3 0.0 2.1 1 1 1 2 2 2 2 Bacterial TniB protein AAA_7 PF12775.7 KFO99945.1 - 0.0037 16.8 0.0 0.01 15.4 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 KFO99945.1 - 0.0063 15.9 0.1 0.015 14.7 0.0 1.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KFO99945.1 - 0.0066 15.9 0.1 0.015 14.7 0.0 1.5 2 0 0 2 2 1 1 PhoH-like protein Sigma54_activat PF00158.26 KFO99945.1 - 0.0095 15.7 0.0 0.042 13.5 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 KFO99945.1 - 0.018 14.4 0.0 0.57 9.4 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 KFO99945.1 - 0.022 14.7 0.0 1.4 8.8 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea MCM PF00493.23 KFO99945.1 - 0.026 13.6 0.0 0.044 12.9 0.0 1.4 2 0 0 2 2 2 0 MCM P-loop domain AAA_30 PF13604.6 KFO99945.1 - 0.033 13.9 0.0 0.055 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KFO99945.1 - 0.041 14.3 0.0 0.063 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 KFO99945.1 - 0.049 13.6 0.0 0.068 13.2 0.0 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Torsin PF06309.11 KFO99945.1 - 0.049 13.7 0.0 0.063 13.4 0.0 1.3 1 0 0 1 1 1 0 Torsin Sigma54_activ_2 PF14532.6 KFO99945.1 - 0.053 13.6 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain KAP_NTPase PF07693.14 KFO99945.1 - 0.054 12.7 0.1 0.37 10.0 0.1 1.9 1 1 0 1 1 1 0 KAP family P-loop domain Viral_helicase1 PF01443.18 KFO99945.1 - 0.059 13.1 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.17 KFO99945.1 - 0.068 12.2 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KFO99945.1 - 0.075 13.3 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFO99945.1 - 0.094 13.2 0.0 0.14 12.6 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Guanylate_kin PF00625.21 KFO99945.1 - 0.098 12.3 0.0 0.28 10.8 0.0 1.7 1 1 0 2 2 2 0 Guanylate kinase AFG1_ATPase PF03969.16 KFO99945.1 - 0.1 11.5 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 AFG1-like ATPase AAA_29 PF13555.6 KFO99945.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 KFO99945.1 - 0.11 12.2 0.5 11 5.7 0.1 2.1 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Vps4_C PF09336.10 KFO99946.1 - 3.5e-30 103.8 0.4 5.5e-30 103.1 0.4 1.3 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 KFO99946.1 - 1e-09 38.0 0.0 6.3e-09 35.5 0.0 2.1 2 0 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 KFO99946.1 - 0.00017 22.0 0.0 0.00038 20.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) adh_short PF00106.25 KFO99947.1 - 6.5e-54 182.4 0.0 8.2e-54 182.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFO99947.1 - 2.6e-30 105.7 0.0 3.4e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFO99947.1 - 1.7e-13 50.9 0.0 2.4e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFO99947.1 - 0.0015 18.4 0.0 0.0031 17.4 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KFO99947.1 - 0.0017 18.6 0.1 0.0031 17.7 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 KFO99947.1 - 0.1 12.3 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Bcl-2 PF00452.19 KFO99948.1 - 1.1e-29 103.0 0.2 1.9e-29 102.3 0.2 1.3 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family BH4 PF02180.17 KFO99948.1 - 2.1e-12 46.6 0.3 4.1e-12 45.6 0.3 1.5 1 0 0 1 1 1 1 Bcl-2 homology region 4 Bcl-2_3 PF15286.6 KFO99948.1 - 0.0035 18.0 0.0 0.0052 17.4 0.0 1.3 1 0 0 1 1 1 1 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like MARVEL PF01284.23 KFO99949.1 - 0.036 14.1 3.1 0.053 13.6 3.1 1.3 1 0 0 1 1 1 0 Membrane-associating domain DUF3818 PF12825.7 KFO99949.1 - 0.25 10.3 0.0 0.34 9.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) LRR_8 PF13855.6 KFO99950.1 - 8.9e-38 127.9 46.2 1.4e-08 34.3 0.6 9.2 6 3 3 9 9 9 9 Leucine rich repeat PP2C PF00481.21 KFO99950.1 - 1.3e-32 113.5 0.0 2.4e-32 112.6 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 KFO99950.1 - 7.6e-29 99.3 49.6 9.7e-06 25.9 1.0 11.0 8 1 3 12 12 12 10 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFO99950.1 - 3.3e-10 39.2 38.9 0.73 10.0 1.5 14.0 15 0 0 15 15 15 4 Leucine Rich repeat LRR_1 PF00560.33 KFO99950.1 - 1.5e-07 31.0 47.2 0.66 10.8 0.4 16.0 16 1 0 16 16 15 1 Leucine Rich Repeat PH PF00169.29 KFO99950.1 - 4.6e-06 27.1 0.0 1.1e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF4734 PF15881.5 KFO99950.1 - 0.11 12.6 7.9 1.7 8.8 3.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4734) TFIIA PF03153.13 KFO99950.1 - 0.25 11.3 11.6 0.42 10.5 11.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit JmjC PF02373.22 KFO99950.1 - 0.27 11.7 3.4 0.76 10.2 3.4 1.7 1 0 0 1 1 1 0 JmjC domain, hydroxylase Spt20 PF12090.8 KFO99950.1 - 1.1 8.8 19.4 3.3 7.3 19.4 1.7 1 0 0 1 1 1 0 Spt20 family TERB2 PF15101.6 KFO99950.1 - 2.6 8.1 8.4 7.3 6.6 8.4 1.7 1 0 0 1 1 1 0 Telomere-associated protein TERB2 zf-CCHC PF00098.23 KFO99951.1 - 2.7e-06 27.2 2.4 9e-06 25.5 2.4 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KFO99951.1 - 0.29 11.0 2.6 0.63 9.9 2.6 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 KFO99951.1 - 1.9 8.3 5.1 0.3 10.9 1.1 1.8 2 0 0 2 2 2 0 Zinc knuckle RANK_CRD_2 PF18278.1 KFO99952.1 - 5.4e-28 96.9 8.1 5.4e-28 96.9 8.1 2.5 2 0 0 2 2 2 1 Receptor activator of the NF-KB cysteine-rich repeat domain 2 TNFR_c6 PF00020.18 KFO99952.1 - 8e-15 55.0 39.5 2.2e-05 24.7 0.4 4.7 4 0 0 4 4 4 4 TNFR/NGFR cysteine-rich region HEAT PF02985.22 KFO99953.1 - 3.3e-16 58.0 0.8 0.011 16.0 0.0 6.7 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 KFO99953.1 - 1e-08 35.4 0.1 0.00058 20.2 0.0 3.8 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 KFO99953.1 - 0.00038 20.9 2.6 0.28 11.8 0.0 4.6 5 0 0 5 5 5 1 HEAT-like repeat Cnd1 PF12717.7 KFO99953.1 - 0.044 13.8 0.0 3 7.9 0.0 2.8 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 KFO99953.1 - 0.089 12.7 1.8 0.79 9.6 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) Nuc_H_symport PF03825.16 KFO99953.1 - 0.13 11.2 0.1 5.3 5.9 0.0 2.2 2 0 0 2 2 2 0 Nucleoside H+ symporter TMF_TATA_bd PF12325.8 KFO99953.1 - 0.72 10.1 4.8 1.5 9.1 0.2 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Prefoldin_2 PF01920.20 KFO99953.1 - 1.5 8.8 4.3 1.9 8.5 0.2 2.7 3 0 0 3 3 3 0 Prefoldin subunit DivIC PF04977.15 KFO99953.1 - 1.6 8.5 7.2 0.85 9.4 0.5 2.6 2 0 0 2 2 2 0 Septum formation initiator PigN PF04987.14 KFO99954.1 - 1.5e-134 449.3 48.2 2e-134 448.9 48.2 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KFO99954.1 - 9.9e-15 55.0 0.3 1.1e-12 48.3 0.3 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KFO99954.1 - 3.4e-06 26.6 0.0 5.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KFO99954.1 - 0.00029 20.3 0.0 0.00047 19.6 0.0 1.3 1 0 0 1 1 1 1 Sulfatase TPR_7 PF13176.6 KFO99954.1 - 0.12 12.5 0.1 0.37 10.9 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-RING_5 PF14634.6 KFO99955.1 - 1.1e-07 31.7 11.6 1.1e-07 31.7 11.6 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFO99955.1 - 4.7e-07 29.6 12.7 8.9e-07 28.7 12.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFO99955.1 - 9.1e-07 29.1 13.1 2.1e-06 28.0 13.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFO99955.1 - 2.2e-05 24.4 10.7 4.7e-05 23.3 10.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 KFO99955.1 - 8.4e-05 22.2 4.2 0.07 12.9 0.1 2.6 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFO99955.1 - 0.00062 19.6 12.9 0.0013 18.5 12.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFO99955.1 - 0.0024 18.0 11.7 0.0024 18.0 11.7 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFO99955.1 - 0.007 16.2 8.4 0.021 14.7 8.4 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 VMA21 PF09446.10 KFO99955.1 - 0.045 13.9 0.0 0.099 12.8 0.0 1.5 1 0 0 1 1 1 0 VMA21-like domain zf-RING_10 PF16685.5 KFO99955.1 - 0.067 13.3 8.6 0.13 12.5 8.6 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KFO99955.1 - 2.2 8.1 13.9 8.9 6.2 13.9 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain TNF PF00229.18 KFO99956.1 - 2.4e-10 40.4 0.0 3.8e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Abhydrolase_1 PF00561.20 KFO99957.1 - 5.2e-16 59.1 0.0 2.4e-10 40.5 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFO99957.1 - 7.1e-16 58.2 0.0 2.8e-10 39.9 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 AXE1 PF05448.12 KFO99957.1 - 2.7e-08 32.9 0.0 0.00028 19.7 0.0 3.1 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 KFO99957.1 - 4.6e-06 27.4 0.0 4e-05 24.3 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KFO99957.1 - 0.00011 22.1 0.0 0.0071 16.2 0.0 2.6 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KFO99957.1 - 0.0005 20.0 0.0 0.00067 19.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KFO99957.1 - 0.001 18.7 0.0 0.019 14.6 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KFO99957.1 - 0.0011 18.5 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 KFO99957.1 - 0.0013 18.7 0.0 0.0076 16.2 0.0 2.0 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 KFO99957.1 - 0.0027 17.4 0.0 0.0037 16.9 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 KFO99957.1 - 0.012 15.1 0.0 0.064 12.8 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family Esterase PF00756.20 KFO99957.1 - 0.042 13.5 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF1057 PF06342.12 KFO99957.1 - 0.054 12.5 0.0 0.078 12.0 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) PGAP1 PF07819.13 KFO99957.1 - 0.18 11.5 0.1 0.45 10.2 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein DUF5339 PF17274.2 KFO99957.1 - 0.2 12.5 0.0 0.33 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5339) DNA_ligase_A_M PF01068.21 KFO99958.1 - 1.7e-53 181.3 0.1 3.2e-53 180.4 0.1 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KFO99958.1 - 1.6e-41 142.5 0.4 3.6e-41 141.4 0.4 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KFO99958.1 - 3.4e-19 69.3 0.0 1.7e-18 67.1 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_IV PF11411.8 KFO99958.1 - 1.7e-18 66.4 0.6 3.7e-18 65.3 0.6 1.6 1 0 0 1 1 1 1 DNA ligase IV BRCT_2 PF16589.5 KFO99958.1 - 3.2e-16 59.5 0.1 4.6e-11 43.0 0.0 2.8 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KFO99958.1 - 6.6e-15 55.3 0.3 2.4e-09 37.4 0.0 3.4 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain RNA_ligase PF09414.10 KFO99958.1 - 2.8e-10 40.8 0.0 8.1e-10 39.2 0.0 1.9 2 0 0 2 2 2 1 RNA ligase mRNA_cap_enzyme PF01331.19 KFO99958.1 - 0.019 14.8 0.5 0.25 11.1 0.5 2.4 1 1 0 1 1 1 0 mRNA capping enzyme, catalytic domain Tox-REase-9 PF15650.6 KFO99958.1 - 0.02 15.2 0.0 0.06 13.6 0.0 1.8 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 9 LIG3_BRCT PF16759.5 KFO99958.1 - 0.023 15.0 0.1 0.87 9.9 0.0 2.5 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain SKA1 PF07160.12 KFO99958.1 - 0.24 11.2 3.0 0.28 11.0 1.1 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 ARGLU PF15346.6 KFO99962.1 - 3e-52 176.5 58.7 3e-52 176.5 58.7 2.7 1 1 1 2 2 2 1 Arginine and glutamate-rich 1 Ephrin PF00812.17 KFO99963.1 - 1.4e-51 174.1 0.3 1.4e-50 170.9 0.1 2.0 2 0 0 2 2 2 1 Ephrin TMEM132D_C PF15706.5 KFO99963.1 - 0.002 17.9 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term OSTbeta PF15048.6 KFO99963.1 - 0.024 14.7 0.1 12 6.1 0.0 2.4 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein RIFIN PF02009.16 KFO99963.1 - 0.059 13.3 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 Rifin EphA2_TM PF14575.6 KFO99963.1 - 0.069 14.0 0.0 0.15 13.0 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KFO99963.1 - 0.087 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family ECSCR PF15820.5 KFO99963.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Amnionless PF14828.6 KFO99963.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Amnionless Stevor PF17410.2 KFO99963.1 - 0.16 11.5 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4381 PF14316.6 KFO99963.1 - 0.23 11.7 0.0 0.39 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Yae1_N PF09811.9 KFO99964.1 - 7.2e-18 64.0 63.3 1.8e+04 -28.1 63.3 6.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal HU-CCDC81_euk_2 PF18289.1 KFO99966.1 - 3.1e-23 81.7 0.1 4e-23 81.4 0.1 1.2 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 SBF PF01758.16 KFO99968.1 - 5.4e-46 156.7 17.4 5.4e-46 156.7 17.4 1.7 2 0 0 2 2 2 1 Sodium Bile acid symporter family Toxin_16 PF07945.11 KFO99968.1 - 1.3 8.9 6.2 0.96 9.4 1.2 2.3 2 0 0 2 2 2 0 Janus-atracotoxin Wzy_C_2 PF11846.8 KFO99968.1 - 8.8 6.2 5.9 3.6 7.5 0.1 2.8 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal Methyltransf_16 PF10294.9 KFO99969.1 - 4.5e-33 114.4 0.0 5.5e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KFO99969.1 - 2.4e-07 30.7 0.0 3.3e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFO99969.1 - 0.0011 18.4 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 KFO99969.1 - 0.045 14.5 0.1 0.1 13.4 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KFO99969.1 - 0.11 13.2 0.0 0.23 12.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain XPG_N PF00752.17 KFO99970.1 - 1e-31 109.4 0.0 3.1e-31 107.8 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KFO99970.1 - 2.6e-25 88.6 0.1 1.8e-24 85.9 0.0 2.7 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 KFO99970.1 - 0.011 16.3 0.0 0.12 13.0 0.0 2.8 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Glyco_transf_90 PF05686.12 KFO99972.1 - 2.1e-112 375.9 1.2 2.8e-112 375.5 1.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Filamin PF00630.19 KFO99972.1 - 6.2e-07 30.2 0.0 1.2e-06 29.3 0.0 1.5 1 0 0 1 1 1 1 Filamin/ABP280 repeat Glyco_trans_1_2 PF13524.6 KFO99972.1 - 2.3e-05 24.7 0.0 4.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Hydrolase_4 PF12146.8 KFO99973.1 - 2.8e-06 26.8 0.1 0.062 12.6 0.0 2.5 2 1 1 3 3 3 2 Serine aminopeptidase, S33 DLH PF01738.18 KFO99973.1 - 0.00032 20.3 0.0 0.00081 19.0 0.0 1.7 2 1 0 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.13 KFO99973.1 - 0.0013 18.5 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KFO99973.1 - 0.047 14.3 0.4 0.41 11.2 0.4 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF900 PF05990.12 KFO99973.1 - 0.085 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Methyltransf_16 PF10294.9 KFO99974.1 - 7.8e-30 103.9 0.0 1.1e-29 103.4 0.0 1.0 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KFO99974.1 - 5.5e-05 22.7 0.0 7.4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KFO99974.1 - 6.9e-05 22.7 0.0 0.00015 21.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFO99974.1 - 0.011 16.4 0.0 0.021 15.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KFO99974.1 - 0.021 15.4 0.0 0.041 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 KFO99974.1 - 0.066 12.3 0.0 0.13 11.3 0.0 1.4 1 1 0 1 1 1 0 DREV methyltransferase TehB PF03848.14 KFO99974.1 - 0.083 12.3 0.0 0.15 11.4 0.0 1.4 1 1 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_12 PF08242.12 KFO99974.1 - 0.086 13.6 0.0 0.17 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 KFO99974.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Peptidase_S8 PF00082.22 KFO99975.1 - 1.6e-96 323.1 1.6 2.3e-96 322.6 1.6 1.2 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.8 KFO99975.1 - 5.1e-80 267.4 0.1 1.4e-79 266.0 0.0 1.8 2 0 0 2 2 2 1 Tripeptidyl peptidase II TPPII_N PF12583.8 KFO99975.1 - 8.2e-05 23.2 0.3 0.00017 22.2 0.3 1.4 1 0 0 1 1 1 1 Tripeptidyl peptidase II N terminal RVT_1 PF00078.27 KFO99976.1 - 0.1 12.1 0.0 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) FGF PF00167.18 KFO99977.1 - 6.3e-41 139.4 0.0 7.7e-41 139.1 0.0 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.13 KFO99977.1 - 0.008 16.4 0.0 0.02 15.1 0.0 1.6 2 0 0 2 2 2 1 Fascin domain CDtoxinA PF03498.14 KFO99977.1 - 0.18 11.4 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain EGF_2 PF07974.13 KFO99978.1 - 1.1e-40 137.7 216.2 6.2e-08 32.9 16.8 11.2 9 3 3 12 12 12 9 EGF-like domain I-EGF_1 PF18372.1 KFO99978.1 - 0.0004 20.4 202.6 0.0084 16.2 11.7 12.8 14 1 1 15 15 15 9 Integrin beta epidermal growth factor like domain 1 Ion_trans PF00520.31 KFO99979.1 - 2.8e-125 416.4 91.0 7.1e-42 143.3 13.8 5.1 4 1 1 5 5 5 5 Ion transport protein PKD_channel PF08016.12 KFO99979.1 - 0.0028 16.4 67.5 0.011 14.5 1.3 8.3 7 2 0 7 7 7 4 Polycystin cation channel OAD_gamma PF04277.13 KFO99979.1 - 6.1 7.5 7.8 33 5.2 0.2 4.4 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain TPR_1 PF00515.28 KFO99980.1 - 6.4e-35 117.6 20.3 5.8e-05 22.7 0.1 7.6 7 0 0 7 7 7 7 Tetratricopeptide repeat DUF1736 PF08409.11 KFO99980.1 - 1.5e-33 114.6 3.3 2.9e-33 113.7 3.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_2 PF07719.17 KFO99980.1 - 3.2e-29 98.7 18.0 8.2e-06 25.6 0.5 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 KFO99980.1 - 2e-27 93.1 10.6 1.7e-05 24.6 0.2 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.6 KFO99980.1 - 9.7e-27 91.4 22.0 6.1e-06 26.3 0.3 7.8 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_16 PF13432.6 KFO99980.1 - 3.3e-25 88.4 5.1 1.1e-07 32.4 0.1 4.8 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFO99980.1 - 5.5e-25 86.8 18.4 1.1e-06 28.2 0.6 8.1 2 2 6 8 8 8 5 TPR repeat TPR_12 PF13424.6 KFO99980.1 - 7.6e-19 67.8 13.4 1.5e-06 28.4 0.2 5.8 2 2 4 6 6 6 6 Tetratricopeptide repeat TPR_14 PF13428.6 KFO99980.1 - 2.9e-15 55.6 7.6 0.0044 17.7 0.1 7.9 3 1 6 9 9 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 KFO99980.1 - 9.9e-15 54.8 10.1 2.1e-06 28.1 0.9 5.2 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 KFO99980.1 - 7.8e-14 51.0 22.1 5.7e-05 22.9 0.5 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFO99980.1 - 2e-10 39.9 4.7 2 8.6 0.1 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_4 PF07721.14 KFO99980.1 - 3.1e-05 24.2 0.2 1.4 9.7 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFO99980.1 - 0.00034 19.9 7.4 0.0093 15.2 0.8 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFO99980.1 - 0.0007 19.1 4.4 0.14 11.5 0.3 3.2 1 1 1 3 3 3 1 MalT-like TPR region TPR_9 PF13371.6 KFO99980.1 - 0.001 19.2 2.1 0.12 12.6 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.8 KFO99980.1 - 0.0024 16.9 2.7 0.088 11.7 0.1 2.6 1 1 2 3 3 3 1 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 KFO99980.1 - 0.0043 17.6 3.2 16 6.4 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat FAT PF02259.23 KFO99980.1 - 0.013 14.7 2.0 0.021 14.0 0.9 1.8 1 1 0 1 1 1 0 FAT domain TPR_20 PF14561.6 KFO99980.1 - 0.06 13.7 2.9 1.2 9.5 0.1 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 KFO99980.1 - 0.097 13.1 1.2 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial transcriptional activator domain DUF4919 PF16266.5 KFO99980.1 - 0.15 12.0 0.5 4.1 7.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) ANAPC3 PF12895.7 KFO99980.1 - 1.3 9.3 8.1 4.6 7.5 0.4 3.2 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 KFO99980.1 - 7.4 6.7 7.2 18 5.5 1.0 4.1 3 2 1 4 4 3 0 MIT (microtubule interacting and transport) domain GGACT PF06094.12 KFO99981.1 - 1.1e-22 80.9 0.2 1.2e-22 80.7 0.2 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 KFO99981.1 - 0.0087 16.4 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 AIG2-like family RVT_1 PF00078.27 KFO99982.1 - 0.15 11.6 0.0 0.33 10.4 0.0 1.6 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf_ZIC PF18366.1 KFO99983.1 - 6.9e-26 90.1 1.3 6.9e-26 90.1 1.3 3.9 4 1 0 4 4 4 1 Zic proteins zinc finger domain zf-C2H2 PF00096.26 KFO99983.1 - 4.3e-23 80.4 29.6 4.4e-06 26.9 0.2 5.9 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFO99983.1 - 1.8e-16 59.7 18.6 6.5e-08 32.7 0.3 6.1 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFO99983.1 - 4.4e-14 52.0 24.9 0.0055 17.4 0.2 5.9 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFO99983.1 - 1.7e-06 28.1 16.3 0.059 13.7 0.2 4.9 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFO99983.1 - 4.1e-05 23.5 8.8 0.74 9.9 1.4 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFO99983.1 - 6.1e-05 23.3 13.3 0.0013 19.0 0.7 4.7 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFO99983.1 - 0.0017 18.6 10.4 0.075 13.3 1.7 2.8 1 1 2 3 3 3 3 C2H2-type zinc ribbon FOXP-CC PF16159.5 KFO99983.1 - 0.69 10.6 14.7 15 6.3 0.0 4.9 2 2 2 4 4 4 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 KFO99983.1 - 4.7 7.0 20.9 5.6 6.8 0.0 4.8 4 0 0 4 4 4 0 C2H2-type zinc-finger domain HpcH_HpaI PF03328.14 KFO99984.1 - 4e-48 163.4 0.0 5.3e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KFO99984.1 - 9.4e-11 41.4 0.0 8.8e-07 28.4 0.0 2.2 1 1 1 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold 7tm_1 PF00001.21 KFO99985.1 - 5.8e-48 163.5 13.0 7e-48 163.2 13.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) OapA_N PF08525.11 KFO99985.1 - 0.25 11.3 3.6 0.89 9.6 3.6 2.0 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif 7TM_GPCR_Srd PF10317.9 KFO99985.1 - 1.7 7.7 16.3 0.52 9.4 1.1 2.9 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srd Chordopox_G3 PF06129.12 KFO99985.1 - 1.7 9.4 5.4 0.39 11.4 1.1 2.1 3 0 0 3 3 3 0 Chordopoxvirus G3 protein UBA PF00627.31 KFO99986.1 - 7.5e-12 44.9 0.6 7.5e-12 44.9 0.6 1.9 2 0 0 2 2 2 1 UBA/TS-N domain 7tm_1 PF00001.21 KFO99987.1 - 1.4e-49 168.8 16.5 1.7e-49 168.5 16.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Srg PF02118.21 KFO99987.1 - 0.0014 18.3 18.3 0.0014 18.3 18.3 1.4 1 1 0 1 1 1 1 Srg family chemoreceptor TatC PF00902.18 KFO99987.1 - 1.8 8.3 14.0 1.4 8.7 0.5 3.1 2 1 1 3 3 3 0 Sec-independent protein translocase protein (TatC) 7tm_1 PF00001.21 KFO99988.1 - 3.9e-32 111.6 24.4 5.4e-32 111.2 24.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFO99988.1 - 0.0021 17.7 31.9 0.0032 17.1 30.9 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DHR-2 PF06920.13 KFO99989.1 - 2.3e-211 703.0 8.0 2.3e-211 703.0 8.0 2.3 2 0 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 KFO99989.1 - 1.6e-57 194.4 0.5 5e-57 192.9 0.5 1.9 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 KFO99989.1 - 5.6e-42 142.7 1.0 1.9e-41 141.0 1.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) PH PF00169.29 KFO99989.1 - 3.9e-14 53.0 0.3 1.5e-13 51.2 0.3 2.1 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KFO99989.1 - 3.4e-05 24.2 0.0 0.00018 21.8 0.0 2.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KFO99989.1 - 0.027 14.7 0.1 0.081 13.2 0.1 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain PTR2 PF00854.21 KFO99990.1 - 1.8e-141 471.6 11.4 4.4e-131 437.4 7.0 2.2 2 0 0 2 2 2 2 POT family MFS_2 PF13347.6 KFO99990.1 - 6.3e-07 28.3 8.8 0.00014 20.6 4.4 3.3 2 1 0 2 2 2 2 MFS/sugar transport protein AlgF PF11182.8 KFO99990.1 - 0.00012 21.9 1.7 0.0055 16.5 0.0 2.6 1 1 1 2 2 2 1 Alginate O-acetyl transferase AlgF Ac76 PF05814.11 KFO99990.1 - 0.0034 17.4 0.2 0.019 15.0 0.0 2.4 2 0 0 2 2 2 1 Orf76 (Ac76) DUF1772 PF08592.11 KFO99990.1 - 0.2 12.0 0.1 0.2 12.0 0.1 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF1772) Cyt_c_ox_IV PF12270.8 KFO99990.1 - 2 8.6 7.4 13 5.9 0.0 3.4 4 0 0 4 4 4 0 Cytochrome c oxidase subunit IV Pkinase PF00069.25 KFO99991.1 - 1.9e-72 243.8 0.0 2.5e-72 243.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFO99991.1 - 6.2e-54 183.0 0.0 8.3e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFO99991.1 - 1.5e-05 24.0 0.0 2.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFO99991.1 - 0.00021 20.4 0.1 0.0022 17.0 0.1 2.1 1 1 0 1 1 1 1 Haspin like kinase domain DUF1241 PF06840.11 KFO99991.1 - 0.00097 18.8 0.0 0.0025 17.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Kinase-like PF14531.6 KFO99991.1 - 0.012 14.9 0.1 0.077 12.3 0.0 2.1 2 1 0 2 2 2 0 Kinase-like Kdo PF06293.14 KFO99991.1 - 0.051 12.9 0.1 0.11 11.9 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFO99991.1 - 0.056 13.4 0.0 7.9 6.3 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family RhoGEF PF00621.20 KFO99992.1 - 2e-31 109.6 1.7 4.7e-31 108.4 1.7 1.7 1 0 0 1 1 1 1 RhoGEF domain FERM_C PF09380.10 KFO99992.1 - 1.9e-25 89.1 0.2 5e-25 87.7 0.2 1.8 1 0 0 1 1 1 1 FERM C-terminal PH-like domain PH PF00169.29 KFO99992.1 - 8.8e-23 80.8 2.6 2.9e-13 50.2 0.6 3.1 3 0 0 3 3 2 2 PH domain FA PF08736.11 KFO99992.1 - 6.3e-16 58.2 3.0 1.9e-15 56.6 3.0 1.9 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_M PF00373.18 KFO99992.1 - 5.1e-13 49.5 0.6 5.1e-13 49.5 0.6 2.3 3 0 0 3 3 3 1 FERM central domain FERM_N PF09379.10 KFO99992.1 - 1.7e-08 34.2 0.0 4e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain IQ_SEC7_PH PF16453.5 KFO99992.1 - 2e-06 27.8 0.0 6.5e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 KFO99992.1 - 0.00019 21.3 3.7 0.53 10.1 0.0 3.4 2 1 0 2 2 2 2 Pleckstrin homology domain PH_2 PF08458.10 KFO99992.1 - 0.0037 17.6 0.3 11 6.4 0.0 3.6 3 0 0 3 3 3 1 Plant pleckstrin homology-like region PH_11 PF15413.6 KFO99992.1 - 0.049 14.1 7.3 0.94 9.9 1.3 4.1 4 1 0 4 4 4 0 Pleckstrin homology domain MCLC PF05934.11 KFO99992.1 - 0.15 10.7 2.6 0.22 10.2 2.6 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Importin_rep_4 PF18808.1 KFO99993.1 - 9.7e-27 93.1 1.6 9.7e-27 93.1 1.6 3.5 2 0 0 2 2 2 1 Importin repeat HEAT PF02985.22 KFO99993.1 - 5.4e-18 63.5 8.6 4.6e-05 23.3 0.0 8.7 10 0 0 10 10 8 3 HEAT repeat HEAT_EZ PF13513.6 KFO99993.1 - 3.3e-17 62.6 4.7 9.7e-09 35.6 0.0 7.4 9 1 1 10 10 8 2 HEAT-like repeat HEAT_2 PF13646.6 KFO99993.1 - 3.9e-17 62.4 0.3 1.8e-08 34.6 0.0 6.7 5 2 2 7 7 7 2 HEAT repeats Vac14_Fab1_bd PF12755.7 KFO99993.1 - 1e-12 48.5 8.2 1.9e-06 28.4 0.0 8.5 6 2 3 9 9 9 1 Vacuolar 14 Fab1-binding region Importin_rep_6 PF18829.1 KFO99993.1 - 8.4e-12 45.2 2.1 2.7e-10 40.3 0.2 3.9 4 0 0 4 4 4 1 Importin repeat 6 Cnd1 PF12717.7 KFO99993.1 - 3.7e-08 33.6 3.2 0.0008 19.5 0.1 4.6 3 2 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 KFO99993.1 - 1.9e-06 27.9 4.7 1.5 8.7 0.1 8.1 6 2 3 9 9 9 1 Domain of unknown function (DUF3385) IBN_N PF03810.19 KFO99993.1 - 0.00052 19.9 2.6 0.0014 18.5 0.1 3.2 4 0 0 4 4 4 1 Importin-beta N-terminal domain Importin_rep_5 PF18816.1 KFO99993.1 - 0.0012 19.1 0.1 0.05 13.9 0.0 2.9 2 0 0 2 2 2 1 Importin repeat Arm PF00514.23 KFO99993.1 - 0.0097 15.9 1.8 60 3.9 0.0 5.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat PBP1_TM PF14812.6 KFO99993.1 - 0.024 15.0 0.2 0.024 15.0 0.2 2.1 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RTP1_C1 PF10363.9 KFO99993.1 - 0.024 14.8 1.4 1.4 9.1 0.0 4.3 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Sec7_N PF12783.7 KFO99993.1 - 0.033 14.1 1.6 13 5.6 0.6 4.9 5 1 0 5 5 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal AbiJ_NTD5 PF18865.1 KFO99993.1 - 0.11 12.3 0.5 0.94 9.3 0.4 2.7 2 0 0 2 2 2 0 AbiJ N-terminal domain 5 HEAT_PBS PF03130.16 KFO99993.1 - 1.6 9.6 5.3 33 5.5 0.0 4.5 4 1 0 4 4 3 0 PBS lyase HEAT-like repeat TRADD_N PF09034.10 KFO99994.1 - 1.4e-47 160.4 3.1 2.3e-47 159.6 3.1 1.4 1 0 0 1 1 1 1 TRADD, N-terminal domain Death PF00531.22 KFO99994.1 - 3.1e-08 33.6 0.9 7.6e-08 32.4 0.1 1.9 2 0 0 2 2 2 1 Death domain UPF0183 PF03676.14 KFO99995.1 - 4e-154 513.7 0.5 4.4e-154 513.5 0.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) CBF_beta PF02312.17 KFO99996.1 - 2e-48 164.2 0.1 2.2e-48 164.1 0.1 1.0 1 0 0 1 1 1 1 Core binding factor beta subunit G-alpha PF00503.20 KFO99997.1 - 1.5e-107 359.9 3.5 1.7e-107 359.7 3.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFO99997.1 - 3.5e-13 49.4 0.0 8.4e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFO99997.1 - 0.00058 19.3 0.6 0.00095 18.6 0.6 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region HMG_CoA_synt_C PF08540.10 KFO99997.1 - 0.064 12.9 0.4 0.52 9.9 0.0 2.2 2 1 0 2 2 2 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal Roc PF08477.13 KFO99997.1 - 0.23 11.7 1.1 0.48 10.7 0.1 2.0 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KFO99998.1 - 8.9e-37 127.1 4.7 9.9e-37 126.9 4.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit G2BR PF18442.1 KFO99999.1 - 1.1e-17 63.3 7.9 3.4e-17 61.8 7.9 1.9 1 0 0 1 1 1 1 E3 gp78 Ube2g2-binding region (G2BR) zf-RING_2 PF13639.6 KFO99999.1 - 3e-12 46.7 7.1 3e-12 46.7 7.1 1.9 2 0 0 2 2 1 1 Ring finger domain CUE PF02845.16 KFO99999.1 - 1.4e-10 40.6 0.1 2.9e-10 39.7 0.1 1.5 1 0 0 1 1 1 1 CUE domain zf-C3HC4_2 PF13923.6 KFO99999.1 - 3.2e-10 39.7 6.3 9.2e-10 38.2 6.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFO99999.1 - 4.4e-08 32.9 5.2 8.8e-08 31.9 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFO99999.1 - 9.6e-08 31.8 3.2 2.5e-07 30.5 3.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFO99999.1 - 1.8e-07 31.1 2.4 4.1e-07 29.9 2.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KFO99999.1 - 5.8e-07 29.7 9.7 5.8e-06 26.5 8.8 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KFO99999.1 - 6.2e-07 29.0 1.5 6.2e-07 29.0 1.5 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KFO99999.1 - 1.6e-05 24.8 3.6 3.3e-05 23.8 3.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFO99999.1 - 1.7e-05 24.6 5.4 3.7e-05 23.5 5.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KFO99999.1 - 2e-05 24.1 4.2 6.2e-05 22.5 4.2 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KFO99999.1 - 0.00011 22.1 2.3 0.00039 20.4 2.3 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KFO99999.1 - 0.0027 17.8 4.6 0.0053 16.9 4.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING MRAP PF15183.6 KFO99999.1 - 0.027 14.4 0.3 0.085 12.8 0.3 1.8 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family RINGv PF12906.7 KFO99999.1 - 0.27 11.4 7.6 0.6 10.3 7.6 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KFO99999.1 - 0.46 10.7 5.6 1.4 9.1 5.6 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain TarH PF02203.15 KFO99999.1 - 0.93 9.4 6.0 0.27 11.1 2.2 2.0 2 0 0 2 2 2 0 Tar ligand binding domain homologue NUDIX_2 PF13869.6 KFP00001.1 - 7.5e-73 244.1 0.1 1.7e-72 243.0 0.1 1.5 1 1 0 1 1 1 1 Nucleotide hydrolase Ofd1_CTDD PF10637.9 KFP00002.1 - 1.6e-43 148.9 0.1 3e-37 128.4 0.1 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KFP00002.1 - 5e-33 113.6 0.3 7.8e-30 103.4 0.1 2.3 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KFP00002.1 - 2.7e-14 53.8 0.1 2.5e-13 50.7 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily BBS2_C PF14782.6 KFP00003.1 - 3.8e-177 589.4 0.0 5.1e-176 585.7 0.0 2.2 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 KFP00003.1 - 2.5e-46 156.2 0.0 2.3e-44 149.8 0.0 2.8 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.6 KFP00003.1 - 9.7e-27 92.9 0.0 3e-26 91.3 0.0 1.9 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, N-terminal FG-GAP PF01839.23 KFP00003.1 - 2.6e-06 27.5 0.2 0.0017 18.4 0.1 2.6 2 0 0 2 2 2 2 FG-GAP repeat VCBS PF13517.6 KFP00003.1 - 1.4e-05 25.6 1.3 0.018 15.7 0.5 3.4 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Itfg2 PF15907.5 KFP00003.1 - 0.00032 19.8 0.2 0.26 10.3 0.0 3.0 2 1 1 3 3 3 2 Integrin-alpha FG-GAP repeat-containing protein 2 Metallothio PF00131.20 KFP00004.1 - 1.1e-17 63.9 60.3 1.1e-17 63.8 60.3 1.0 1 0 0 1 1 1 1 Metallothionein Metallothio PF00131.20 KFP00005.1 - 2.3e-16 59.7 62.9 2.5e-16 59.6 62.9 1.0 1 0 0 1 1 1 1 Metallothionein Nic96 PF04097.14 KFP00006.1 - 1.8e-195 651.0 0.3 2.6e-195 650.5 0.3 1.2 1 0 0 1 1 1 1 Nup93/Nic96 Nup84_Nup100 PF04121.13 KFP00006.1 - 0.00065 17.9 0.3 0.0013 17.0 0.3 1.4 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 AA_permease PF00324.21 KFP00007.1 - 9.3e-137 456.5 34.8 1.1e-136 456.2 34.8 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KFP00007.1 - 3.6e-115 385.4 0.0 1.1e-50 173.0 0.0 3.1 2 1 1 3 3 3 3 Solute carrier family 12 AA_permease_N PF08403.10 KFP00007.1 - 4e-18 64.7 0.0 1.5e-17 62.9 0.0 1.9 2 0 0 2 2 2 1 Amino acid permease N-terminal Tmemb_170 PF10190.9 KFP00008.1 - 2e-37 127.8 7.1 2.2e-37 127.7 7.1 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 Chromate_transp PF02417.15 KFP00008.1 - 0.091 12.9 7.3 0.1 12.8 7.3 1.1 1 0 0 1 1 1 0 Chromate transporter DUF4235 PF14019.6 KFP00008.1 - 0.091 12.9 1.8 0.83 9.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) DUF5489 PF17592.2 KFP00008.1 - 0.28 11.7 4.6 0.4 11.3 4.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5489) BCNT PF07572.12 KFP00009.1 - 3.6e-30 103.9 3.2 3.9e-30 103.7 0.5 2.3 2 0 0 2 2 2 1 Bucentaur or craniofacial development Trypsin PF00089.26 KFP00010.1 - 6.1e-50 170.1 0.1 6.7e-50 169.9 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFP00010.1 - 0.0013 19.7 0.0 0.0017 19.3 0.0 1.1 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFP00010.1 - 0.002 18.5 0.0 0.0032 17.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF316 PF03761.15 KFP00010.1 - 0.062 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 Trypsin PF00089.26 KFP00011.1 - 0.013 15.3 0.1 0.014 15.2 0.1 1.0 1 0 0 1 1 1 0 Trypsin C1q PF00386.21 KFP00012.1 - 2.6e-18 66.5 0.0 2.8e-18 66.3 0.0 1.0 1 0 0 1 1 1 1 C1q domain TNF PF00229.18 KFP00012.1 - 0.12 12.4 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family LRR_8 PF13855.6 KFP00013.1 - 4.5e-27 93.6 37.0 3.2e-09 36.4 4.1 3.5 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KFP00013.1 - 4.9e-17 61.7 20.4 7e-07 29.5 2.6 4.2 1 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP00013.1 - 1.8e-09 36.8 15.0 1.3 9.8 0.1 6.6 6 1 0 6 6 6 5 Leucine Rich Repeat LRR_6 PF13516.6 KFP00013.1 - 3.8e-06 26.5 18.6 3.8 7.8 0.0 6.4 6 0 0 6 6 6 5 Leucine Rich repeat DNA_methylase PF00145.17 KFP00014.1 - 3e-29 102.4 0.0 4.3e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Filament PF00038.21 KFP00015.1 - 3.3e-114 381.7 51.1 3.9e-114 381.4 51.1 1.1 1 0 0 1 1 1 1 Intermediate filament protein Filament_head PF04732.14 KFP00015.1 - 3.2e-13 50.3 0.3 6.5e-13 49.4 0.3 1.5 1 0 0 1 1 1 1 Intermediate filament head (DNA binding) region DUF1664 PF07889.12 KFP00015.1 - 0.00053 20.0 23.0 0.0016 18.5 1.3 3.8 3 1 0 4 4 3 2 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 KFP00015.1 - 0.0055 16.8 53.6 0.072 13.2 14.2 4.3 2 1 2 4 4 4 2 TPR/MLP1/MLP2-like protein DUF4200 PF13863.6 KFP00015.1 - 0.0095 16.3 15.4 0.0095 16.3 15.4 4.1 1 1 2 3 3 2 1 Domain of unknown function (DUF4200) DUF4515 PF14988.6 KFP00015.1 - 0.016 15.0 44.8 0.054 13.3 31.4 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4515) FPP PF05911.11 KFP00015.1 - 0.016 13.4 35.2 0.032 12.5 17.1 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Jnk-SapK_ap_N PF09744.9 KFP00015.1 - 0.018 15.3 45.2 0.36 11.0 18.3 4.0 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Golgin_A5 PF09787.9 KFP00015.1 - 0.023 14.2 42.9 0.26 10.7 22.7 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 bZIP_1 PF00170.21 KFP00015.1 - 0.04 14.0 28.0 2.2 8.4 1.4 6.0 4 1 1 5 5 5 0 bZIP transcription factor Atg14 PF10186.9 KFP00015.1 - 0.069 12.2 27.5 2.6 7.0 12.2 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF573 PF04504.14 KFP00015.1 - 0.11 13.2 9.3 1.5 9.5 1.0 3.7 2 2 1 3 3 3 0 Protein of unknown function, DUF573 Trimer_CC PF08954.11 KFP00015.1 - 0.15 11.6 8.2 11 5.7 1.3 3.9 3 0 0 3 3 3 0 Trimerisation motif Laminin_II PF06009.12 KFP00015.1 - 0.15 12.1 27.5 3.2 7.8 1.4 3.6 1 1 1 3 3 3 0 Laminin Domain II Baculo_PEP_C PF04513.12 KFP00015.1 - 0.18 11.9 19.2 0.5 10.4 1.9 4.5 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 KFP00015.1 - 0.31 10.3 48.2 0.046 13.1 14.7 4.0 1 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.8 KFP00015.1 - 0.34 8.4 40.9 0.93 6.9 40.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF5082 PF16888.5 KFP00015.1 - 0.38 11.0 28.1 0.12 12.7 9.8 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF5082) DUF600 PF04634.12 KFP00015.1 - 0.5 10.4 5.3 0.16 12.0 0.4 2.7 1 1 1 3 3 3 0 Protein of unknown function, DUF600 HALZ PF02183.18 KFP00015.1 - 0.51 10.6 0.1 0.14 12.4 2.1 6.7 8 1 0 8 8 5 0 Homeobox associated leucine zipper HOOK PF05622.12 KFP00015.1 - 0.53 8.4 44.7 0.097 10.8 36.9 2.0 1 1 1 2 2 2 0 HOOK protein HMMR_N PF15905.5 KFP00015.1 - 1 8.8 40.0 0.037 13.5 10.4 2.8 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Rab5-bind PF09311.11 KFP00015.1 - 1.4 8.2 44.5 0.38 10.1 12.5 3.3 1 1 0 2 2 2 0 Rabaptin-like protein DUF948 PF06103.11 KFP00015.1 - 1.8 8.9 12.3 33 4.8 0.1 4.7 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF948) MdcG PF10620.9 KFP00015.1 - 1.9 8.2 6.5 0.18 11.6 0.4 2.4 3 0 0 3 3 3 0 Phosphoribosyl-dephospho-CoA transferase MdcG DUF1759 PF03564.15 KFP00015.1 - 1.9 8.4 15.7 0.94 9.4 0.7 3.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1759) CENP-F_leu_zip PF10473.9 KFP00015.1 - 2.7 8.0 44.7 0.091 12.8 5.2 3.7 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KFP00015.1 - 2.7 6.8 44.8 0.66 8.8 13.9 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein FAM184 PF15665.5 KFP00015.1 - 3 7.6 46.9 2.2 8.0 2.9 3.5 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B DUF4266 PF14086.6 KFP00015.1 - 3.1 8.8 5.3 1 10.4 0.3 2.9 3 0 0 3 3 1 0 Domain of unknown function (DUF4266) EspB PF05802.11 KFP00015.1 - 3.2 7.7 16.3 23 4.9 15.2 2.8 1 1 0 1 1 1 0 Enterobacterial EspB protein DUF812 PF05667.11 KFP00015.1 - 3.4 6.4 43.3 8.5 5.1 24.6 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF812) JIP_LZII PF16471.5 KFP00015.1 - 4.4 7.6 34.2 1.2 9.3 2.7 6.2 1 1 3 6 6 6 0 JNK-interacting protein leucine zipper II Fib_alpha PF08702.10 KFP00015.1 - 5 7.3 32.8 1.3 9.2 10.8 3.7 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family CENP-H PF05837.12 KFP00015.1 - 9.8 6.6 39.7 5.7 7.4 3.9 4.9 1 1 4 5 5 5 0 Centromere protein H (CENP-H) Glyco_transf_29 PF00777.18 KFP00016.1 - 1.4e-81 273.8 0.0 2.3e-81 273.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) PTPLA PF04387.14 KFP00017.1 - 1.7e-59 200.2 13.5 2e-59 200.0 13.5 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA VHS PF00790.19 KFP00018.1 - 4.3e-44 149.8 1.7 5.7e-44 149.4 0.1 1.9 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.28 KFP00018.1 - 4e-16 58.3 0.1 7.7e-16 57.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP00018.1 - 1.5e-12 47.0 0.0 2.9e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFP00018.1 - 1.6e-11 43.9 0.0 2.9e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.20 KFP00018.1 - 6.9e-05 22.5 1.7 0.00019 21.1 1.7 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif GAT PF03127.14 KFP00018.1 - 0.021 15.1 3.7 0.055 13.8 3.7 1.8 1 0 0 1 1 1 0 GAT domain SH3_10 PF17902.1 KFP00018.1 - 0.028 14.5 0.0 0.069 13.2 0.0 1.6 1 0 0 1 1 1 0 SH3 domain HEAT PF02985.22 KFP00018.1 - 0.43 11.0 1.5 1.3 9.5 0.1 2.4 2 0 0 2 2 2 0 HEAT repeat Lectin_C PF00059.21 KFP00019.1 - 3.2e-78 259.5 10.1 3.7e-25 88.7 0.2 5.2 5 0 0 5 5 5 4 Lectin C-type domain fn2 PF00040.19 KFP00019.1 - 1.9e-14 53.6 9.9 1.9e-14 53.6 9.9 2.5 2 0 0 2 2 2 1 Fibronectin type II domain UL45 PF05473.12 KFP00019.1 - 3.8e-10 39.8 0.2 3e-06 27.0 0.0 3.5 3 0 0 3 3 3 2 UL45 protein, carbohydrate-binding C-type lectin-like Ricin_B_lectin PF00652.22 KFP00019.1 - 3.5e-09 37.0 0.2 9.2e-09 35.6 0.2 1.8 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Xlink PF00193.17 KFP00019.1 - 6.6e-05 23.2 3.6 0.28 11.6 0.2 4.9 5 1 1 6 6 6 2 Extracellular link domain Chordopox_A33R PF05966.12 KFP00019.1 - 0.0073 15.6 0.6 0.25 10.6 0.0 3.2 4 0 0 4 4 4 1 Chordopoxvirus A33R protein Lectin_C PF00059.21 KFP00020.1 - 1.9e-159 520.8 46.4 6.8e-23 81.5 0.5 9.2 9 0 0 9 9 9 8 Lectin C-type domain UL45 PF05473.12 KFP00020.1 - 4.4e-15 55.9 8.0 0.0015 18.2 0.1 6.2 5 1 1 6 6 6 4 UL45 protein, carbohydrate-binding C-type lectin-like fn2 PF00040.19 KFP00020.1 - 1.6e-13 50.6 3.3 1.6e-13 50.6 3.3 2.8 2 0 0 2 2 2 1 Fibronectin type II domain Xlink PF00193.17 KFP00020.1 - 4e-09 36.7 13.8 0.28 11.6 0.1 8.4 8 2 1 9 9 9 2 Extracellular link domain Ricin_B_lectin PF00652.22 KFP00020.1 - 2.6e-07 30.9 2.2 9.9e-07 29.1 2.2 2.1 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Chordopox_A33R PF05966.12 KFP00020.1 - 5.1e-06 25.9 12.5 0.61 9.3 0.1 6.5 7 0 0 7 7 7 3 Chordopoxvirus A33R protein Intimin_C PF07979.11 KFP00020.1 - 0.011 16.2 7.4 69 3.9 0.0 6.6 8 0 0 8 8 8 0 Intimin C-type lectin domain CDtoxinA PF03498.14 KFP00020.1 - 0.43 10.2 7.4 0.32 10.6 1.9 3.1 3 0 0 3 3 3 0 Cytolethal distending toxin A/C domain DUF4846 PF16138.5 KFP00020.1 - 0.43 10.0 7.1 16 4.9 0.1 4.3 5 0 0 5 5 5 0 Domain of unknown function (4846) Lectin_C PF00059.21 KFP00021.1 - 1.9e-76 253.7 10.4 8.3e-26 90.8 0.9 5.2 5 0 0 5 5 5 4 Lectin C-type domain fn2 PF00040.19 KFP00021.1 - 1.2e-16 60.7 9.1 1.2e-16 60.7 9.1 2.7 2 0 0 2 2 2 1 Fibronectin type II domain Ricin_B_lectin PF00652.22 KFP00021.1 - 1.7e-09 38.0 0.7 1.7e-09 38.0 0.7 2.5 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain UL45 PF05473.12 KFP00021.1 - 1e-07 31.8 3.7 2.4e-05 24.1 0.0 3.9 4 1 1 5 5 5 2 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.12 KFP00021.1 - 0.0016 17.8 3.1 0.45 9.8 0.0 3.9 4 0 0 4 4 4 1 Chordopoxvirus A33R protein Xlink PF00193.17 KFP00021.1 - 0.0024 18.2 13.8 0.16 12.4 0.2 5.7 4 3 2 7 7 7 2 Extracellular link domain Lectin_C PF00059.21 KFP00022.1 - 5.6e-78 258.7 9.1 1.2e-20 74.2 0.4 4.3 4 0 0 4 4 4 4 Lectin C-type domain fn2 PF00040.19 KFP00022.1 - 1.3e-17 63.8 6.3 4.9e-17 61.9 6.3 2.1 1 0 0 1 1 1 1 Fibronectin type II domain UL45 PF05473.12 KFP00022.1 - 1.6e-08 34.4 0.4 0.0034 17.0 0.0 3.5 2 1 1 3 3 3 2 UL45 protein, carbohydrate-binding C-type lectin-like Xlink PF00193.17 KFP00022.1 - 3.1e-05 24.3 11.5 0.47 10.9 0.1 5.6 5 1 0 5 5 5 2 Extracellular link domain Chordopox_A33R PF05966.12 KFP00022.1 - 0.00025 20.4 3.7 0.0079 15.5 0.1 3.4 4 0 0 4 4 4 1 Chordopoxvirus A33R protein CBM9_2 PF16011.5 KFP00022.1 - 0.034 13.9 0.1 0.063 13.0 0.1 1.4 1 0 0 1 1 1 0 Carbohydrate-binding family 9 Adeno_E3_CR1 PF02440.15 KFP00022.1 - 0.95 9.3 4.7 0.26 11.1 0.1 2.4 3 0 0 3 3 3 0 Adenovirus E3 region protein CR1 Lectin_C PF00059.21 KFP00023.1 - 1.3e-18 67.7 1.1 2.4e-18 66.8 0.1 1.7 2 0 0 2 2 2 1 Lectin C-type domain MFS_Mycoplasma PF07672.13 KFP00023.1 - 0.0063 15.8 0.7 0.0089 15.3 0.7 1.2 1 0 0 1 1 1 1 Mycoplasma MFS transporter XK-related PF09815.9 KFP00023.1 - 0.013 14.6 0.5 0.016 14.3 0.5 1.1 1 0 0 1 1 1 0 XK-related protein ECSCR PF15820.5 KFP00023.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF4366 PF14283.6 KFP00023.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) LapA_dom PF06305.11 KFP00023.1 - 0.18 11.6 1.1 0.38 10.6 1.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Tmemb_55A PF09788.9 KFP00023.1 - 0.28 10.2 1.3 0.38 9.8 1.3 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A ZIP4_domain PF18292.1 KFP00024.1 - 1.4e-57 194.2 4.3 7.1e-53 178.9 0.7 2.3 2 0 0 2 2 2 2 Zinc transporter ZIP4 domain Zip PF02535.22 KFP00024.1 - 1.9e-56 191.7 10.1 3.2e-56 191.0 10.1 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter DUF5054 PF16477.5 KFP00024.1 - 0.0091 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5054) Guanylate_kin PF00625.21 KFP00025.1 - 3.2e-50 170.4 0.2 6.8e-50 169.3 0.2 1.6 1 0 0 1 1 1 1 Guanylate kinase VGCC_beta4Aa_N PF12052.8 KFP00025.1 - 5.3e-23 80.8 6.6 5.3e-23 80.8 6.6 3.0 3 0 0 3 3 3 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal SH3_1 PF00018.28 KFP00025.1 - 0.0016 18.0 0.1 0.0063 16.1 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFP00025.1 - 0.16 11.7 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Methyltr_RsmB-F PF01189.17 KFP00026.1 - 1e-46 159.2 0.0 1.7e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 KFP00026.1 - 1.3e-08 34.7 0.0 2.4e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KFP00026.1 - 5.4e-08 33.1 0.0 1.1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PUA PF01472.20 KFP00026.1 - 0.00013 21.8 0.1 0.00028 20.8 0.1 1.5 1 0 0 1 1 1 1 PUA domain DUF2431 PF10354.9 KFP00026.1 - 0.00038 20.8 0.0 0.00069 19.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) PCMT PF01135.19 KFP00026.1 - 0.0022 17.8 0.0 0.0053 16.5 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KFP00026.1 - 0.004 17.8 0.2 0.046 14.4 0.1 2.6 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 KFP00026.1 - 0.0076 15.8 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Ubie_methyltran PF01209.18 KFP00026.1 - 0.054 12.8 0.0 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KFP00026.1 - 0.13 12.9 0.0 1.1 9.9 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KFP00026.1 - 0.17 11.5 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Arf PF00025.21 KFP00027.1 - 7e-65 217.7 0.1 7.7e-65 217.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFP00027.1 - 9.2e-16 58.2 0.1 1.2e-15 57.8 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP00027.1 - 3.8e-14 52.6 0.0 4.3e-14 52.4 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFP00027.1 - 7.6e-13 48.3 0.0 1e-12 47.9 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFP00027.1 - 5.7e-09 35.6 0.3 3.6e-06 26.4 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KFP00027.1 - 3e-07 30.0 0.2 3.5e-07 29.8 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP00027.1 - 3.3e-07 30.4 0.0 4.5e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP00027.1 - 0.0021 17.6 0.1 0.03 13.9 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 KFP00027.1 - 0.015 15.3 0.1 0.038 14.0 0.0 1.7 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.18 KFP00027.1 - 0.094 12.2 0.5 0.36 10.4 0.4 1.8 1 1 1 2 2 2 0 Ferrous iron transport protein B ATPase PF06745.13 KFP00027.1 - 0.13 11.6 0.3 0.55 9.5 0.0 1.8 1 1 1 2 2 2 0 KaiC Yae1_N PF09811.9 KFP00028.1 - 3.2e-17 61.9 61.1 1.8e+04 -25.9 61.1 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Yae1_N PF09811.9 KFP00029.1 - 9.2e-17 60.5 58.9 1.8e+04 -23.9 58.9 5.6 1 1 0 1 1 1 0 Essential protein Yae1, N terminal MAM PF00629.23 KFP00030.1 - 9.4e-19 67.9 1.3 1e-18 67.7 1.3 1.0 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu MAM PF00629.23 KFP00031.1 - 3.9e-39 134.1 0.0 4.4e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu MAM PF00629.23 KFP00032.1 - 3.1e-22 79.2 1.9 3.5e-22 79.0 1.9 1.0 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Viral_Beta_CD PF04530.12 KFP00033.1 - 0.014 15.7 0.0 0.016 15.5 0.0 1.2 1 0 0 1 1 1 0 Viral Beta C/D like family PSI PF01437.25 KFP00034.1 - 9e-08 32.5 10.9 1.5e-07 31.8 10.9 1.3 1 0 0 1 1 1 1 Plexin repeat MGC-24 PF05283.11 KFP00034.1 - 0.016 15.7 10.3 0.043 14.3 10.3 1.7 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF5305 PF17231.2 KFP00034.1 - 0.076 12.4 0.5 0.13 11.6 0.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF2157 PF09925.9 KFP00034.1 - 0.14 11.9 0.3 0.23 11.2 0.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) PSI_integrin PF17205.3 KFP00034.1 - 1.8 8.4 9.1 3.2 7.6 9.1 1.4 1 0 0 1 1 1 0 Integrin plexin domain Nebulin PF00880.18 KFP00035.1 - 3.3e-32 109.9 2.2 1.7e-12 47.0 0.1 3.5 3 0 0 3 3 3 3 Nebulin repeat SH3_9 PF14604.6 KFP00035.1 - 2.9e-16 59.1 0.1 4.7e-16 58.4 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP00035.1 - 2e-13 49.7 0.0 4e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain LIM PF00412.22 KFP00035.1 - 1e-06 28.9 6.3 1e-06 28.9 6.3 1.6 2 0 0 2 2 2 1 LIM domain SH3_2 PF07653.17 KFP00035.1 - 1.8e-05 24.4 0.0 3.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain EPOP PF15223.6 KFP00036.1 - 1.5e-119 400.1 9.7 2.2e-119 399.6 9.7 1.2 1 0 0 1 1 1 1 Elongin BC and Polycomb repressive complex 2-associated protein Ski_Sno PF02437.17 KFP00036.1 - 4.9e-15 55.2 0.1 1e-14 54.2 0.1 1.5 1 0 0 1 1 1 1 SKI/SNO/DAC family zf-HC5HC2H_2 PF13832.6 KFP00037.1 - 7.8e-31 106.5 21.1 2e-30 105.1 11.4 2.4 2 0 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFP00037.1 - 4.9e-20 71.6 10.6 4.9e-20 71.6 10.6 3.3 2 1 1 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KFP00037.1 - 2.8e-13 49.2 4.2 2.8e-13 49.2 4.2 2.7 3 0 0 3 3 3 1 PHD-finger PHD PF00628.29 KFP00037.1 - 1.9e-08 34.1 9.7 1.9e-08 34.1 9.7 3.0 2 1 0 2 2 2 1 PHD-finger zf-RING-like PF08746.11 KFP00037.1 - 5.3 7.4 12.8 6.2 7.2 3.2 3.0 2 0 0 2 2 2 0 RING-like domain RAWUL PF16207.5 KFP00039.1 - 1.1e-21 77.3 0.6 2.7e-21 76.0 0.6 1.7 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 KFP00039.1 - 0.011 15.6 2.5 0.02 14.7 2.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP00039.1 - 0.047 13.6 2.7 0.079 12.8 2.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP00039.1 - 0.088 13.2 2.2 0.18 12.2 2.2 1.6 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 KFP00039.1 - 0.24 11.7 1.7 0.53 10.6 1.7 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFP00039.1 - 0.7 9.8 4.9 1.5 8.7 4.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Arm PF00514.23 KFP00040.1 - 6.9e-41 137.1 18.0 7.7e-09 35.3 0.0 9.0 9 0 0 9 9 9 6 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KFP00040.1 - 1.3e-17 62.3 9.9 0.06 13.6 0.0 8.6 9 0 0 9 9 8 4 HEAT repeat HEAT_2 PF13646.6 KFP00040.1 - 1.7e-16 60.4 6.4 0.0013 19.1 0.2 5.0 2 2 4 6 6 6 5 HEAT repeats HEAT_EZ PF13513.6 KFP00040.1 - 1.5e-15 57.3 11.8 0.00025 21.5 0.0 6.8 4 2 4 8 8 7 5 HEAT-like repeat Cnd1 PF12717.7 KFP00040.1 - 4.9e-14 52.7 0.7 0.069 13.2 0.0 5.1 1 1 4 5 5 5 4 non-SMC mitotic condensation complex subunit 1 DNA_alkylation PF08713.11 KFP00040.1 - 1.5e-08 34.6 0.0 0.67 9.6 0.0 4.3 2 1 1 4 4 4 3 DNA alkylation repair enzyme Adaptin_N PF01602.20 KFP00040.1 - 5.9e-08 31.7 4.3 0.032 12.8 1.6 3.6 2 1 1 3 3 3 3 Adaptin N terminal region CHASE6_C PF17150.4 KFP00040.1 - 5.8e-07 30.1 0.2 2 9.1 0.0 6.1 5 2 1 6 6 6 1 C-terminal domain of two-partite extracellular sensor domain Atx10homo_assoc PF09759.9 KFP00040.1 - 8e-06 25.8 0.1 1.9 8.5 0.0 4.6 3 2 2 5 5 5 1 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.8 KFP00040.1 - 6.4e-05 22.6 0.1 0.086 12.4 0.0 3.5 2 1 1 4 4 4 1 CLASP N terminal HEAT_PBS PF03130.16 KFP00040.1 - 0.00011 22.6 9.3 0.21 12.3 0.2 5.9 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.9 KFP00040.1 - 0.00033 19.3 2.2 0.0063 15.1 0.6 2.7 1 1 2 3 3 3 1 Proteasome non-ATPase 26S subunit Rcd1 PF04078.13 KFP00040.1 - 0.001 18.4 0.5 0.65 9.2 0.1 3.6 3 2 1 4 4 4 1 Cell differentiation family, Rcd1-like V-ATPase_H_C PF11698.8 KFP00040.1 - 0.0015 18.6 0.7 1 9.5 0.1 3.8 4 0 0 4 4 4 1 V-ATPase subunit H RTP1_C1 PF10363.9 KFP00040.1 - 0.0015 18.7 2.0 0.042 14.0 0.3 3.5 4 1 0 4 4 3 1 Required for nuclear transport of RNA pol II C-terminus 1 XPC-binding PF09280.11 KFP00040.1 - 0.0085 15.8 0.3 25 4.7 0.0 4.7 5 0 0 5 5 5 0 XPC-binding domain API5 PF05918.11 KFP00040.1 - 0.0085 14.9 1.8 3.6 6.3 0.0 3.0 2 1 1 3 3 3 2 Apoptosis inhibitory protein 5 (API5) DUF3731 PF12531.8 KFP00040.1 - 0.014 15.2 0.3 2.8 7.7 0.1 3.1 3 0 0 3 3 3 0 DNA-K related protein Mo25 PF08569.11 KFP00040.1 - 0.021 14.2 0.3 1 8.7 0.3 2.9 1 1 0 1 1 1 0 Mo25-like TPR_16 PF13432.6 KFP00040.1 - 0.11 13.1 4.0 12 6.6 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TetR_C_25 PF17933.1 KFP00040.1 - 0.16 12.3 0.0 0.4 11.0 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MMS19_C PF12460.8 KFP00040.1 - 0.2 10.7 6.6 0.6 9.2 0.5 2.9 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal DUF3361 PF11841.8 KFP00040.1 - 0.23 11.4 3.5 1.1 9.2 0.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) PIP5K PF01504.18 KFP00041.1 - 7.4e-77 258.2 0.1 9.8e-77 257.8 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Arm PF00514.23 KFP00042.1 - 2.2e-43 145.0 20.5 2.6e-06 27.2 0.0 11.8 11 0 0 11 11 11 7 Armadillo/beta-catenin-like repeat EDR1 PF14381.6 KFP00042.1 - 4.3e-40 137.6 0.1 2.9e-39 134.9 0.0 2.3 3 0 0 3 3 3 1 Ethylene-responsive protein kinase Le-CTR1 HEAT_2 PF13646.6 KFP00042.1 - 1e-26 93.1 9.4 5.3e-06 26.7 1.3 7.0 1 1 4 7 7 7 7 HEAT repeats HEAT_EZ PF13513.6 KFP00042.1 - 6e-17 61.8 12.3 0.012 16.1 0.2 8.0 8 1 1 9 9 9 4 HEAT-like repeat HEAT PF02985.22 KFP00042.1 - 1.1e-16 59.5 16.6 0.032 14.5 0.2 10.0 10 0 0 10 10 10 5 HEAT repeat Adaptin_N PF01602.20 KFP00042.1 - 3.5e-12 45.7 2.3 1.1e-08 34.2 0.8 3.1 1 1 3 4 4 4 4 Adaptin N terminal region V-ATPase_H_C PF11698.8 KFP00042.1 - 5.4e-10 39.4 3.5 0.15 12.1 0.0 6.5 2 2 6 8 8 8 2 V-ATPase subunit H Cnd1 PF12717.7 KFP00042.1 - 1.7e-09 37.9 4.0 0.48 10.4 0.1 5.6 1 1 4 5 5 5 4 non-SMC mitotic condensation complex subunit 1 Arm_2 PF04826.13 KFP00042.1 - 2e-08 34.0 2.6 0.00065 19.2 0.4 4.3 2 2 2 4 4 4 2 Armadillo-like V-ATPase_H_N PF03224.14 KFP00042.1 - 1.4e-07 31.1 0.5 0.0043 16.4 0.0 3.3 1 1 1 3 3 3 2 V-ATPase subunit H Proteasom_PSMB PF10508.9 KFP00042.1 - 0.00073 18.2 2.3 0.061 11.8 1.1 2.9 2 1 0 2 2 2 1 Proteasome non-ATPase 26S subunit Aconitase_B_N PF11791.8 KFP00042.1 - 0.0023 18.0 1.4 0.76 9.8 0.1 3.4 2 1 1 3 3 3 1 Aconitate B N-terminal domain Atx10homo_assoc PF09759.9 KFP00042.1 - 0.0049 16.9 0.7 2.5 8.2 0.0 3.9 3 1 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain RasGEF_N_2 PF14663.6 KFP00042.1 - 0.0096 16.3 4.3 23 5.4 0.1 5.4 4 2 1 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF3361 PF11841.8 KFP00042.1 - 0.08 12.9 6.4 6 6.8 0.2 4.7 2 2 3 5 5 5 0 Domain of unknown function (DUF3361) Ric8 PF10165.9 KFP00042.1 - 0.099 11.7 1.2 1.3 8.0 1.2 2.2 1 1 0 1 1 1 0 Guanine nucleotide exchange factor synembryn RTP1_C1 PF10363.9 KFP00042.1 - 0.45 10.7 4.1 26 5.1 0.1 3.9 2 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 UNC45-central PF11701.8 KFP00042.1 - 9 6.2 9.0 6.2 6.8 0.7 4.0 2 2 1 3 3 3 0 Myosin-binding striated muscle assembly central SelR PF01641.18 KFP00043.1 - 1.8e-30 105.5 0.1 2e-30 105.4 0.1 1.0 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 KFP00043.1 - 0.054 13.2 0.1 0.068 12.9 0.1 1.3 1 1 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Yippee-Mis18 PF03226.14 KFP00043.1 - 0.059 13.6 0.0 0.063 13.5 0.0 1.2 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HECT_2 PF09814.9 KFP00043.1 - 0.12 11.2 0.0 0.12 11.2 0.0 1.0 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding OTU PF02338.19 KFP00045.1 - 8.6e-25 87.7 0.0 1.8e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KFP00045.1 - 0.0075 15.8 0.0 0.62 9.5 0.3 2.2 1 1 1 2 2 2 2 Peptidase C65 Otubain AIP3 PF03915.13 KFP00046.1 - 2e-13 50.2 11.6 2.4e-09 36.8 0.0 6.2 5 2 1 7 7 7 3 Actin interacting protein 3 RhoGAP PF00620.27 KFP00047.1 - 1.5e-50 171.0 0.1 3e-50 170.0 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain PDZ_6 PF17820.1 KFP00047.1 - 3.3e-15 55.7 0.1 1.5e-14 53.6 0.0 2.2 2 0 0 2 2 2 1 PDZ domain PH_9 PF15410.6 KFP00047.1 - 4.2e-14 52.9 0.0 1.3e-13 51.3 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFP00047.1 - 9.3e-13 48.6 3.3 1.6e-12 47.9 0.2 2.8 2 0 0 2 2 2 1 PH domain PDZ PF00595.24 KFP00047.1 - 7.7e-10 39.0 0.0 2.8e-09 37.2 0.0 2.0 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP00047.1 - 5.8e-06 26.5 0.0 2e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PH_11 PF15413.6 KFP00047.1 - 0.00063 20.1 0.0 0.0049 17.3 0.0 2.7 1 0 0 1 1 1 1 Pleckstrin homology domain Pribosyltran PF00156.27 KFP00048.1 - 1.2e-14 54.1 0.0 3.4e-06 26.7 0.0 2.0 2 0 0 2 2 2 2 Phosphoribosyl transferase domain Enkurin PF13864.6 KFP00049.1 - 7.2e-28 96.9 12.0 7.2e-28 96.9 12.0 2.9 3 0 0 3 3 3 1 Calmodulin-binding DctP PF03480.13 KFP00049.1 - 0.0086 15.5 2.0 0.015 14.7 2.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 AAA_9 PF12781.7 KFP00049.1 - 0.011 14.8 1.2 0.011 14.8 1.2 1.8 2 0 0 2 2 2 0 ATP-binding dynein motor region UPF0203 PF05254.12 KFP00049.1 - 1.6 9.0 4.9 0.41 10.9 0.8 2.1 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0203) SKI PF01202.22 KFP00050.1 - 9.8e-34 116.8 0.0 1.7e-33 116.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase Thr_synth_N PF14821.6 KFP00050.1 - 3.9e-14 52.6 0.0 1.1e-13 51.2 0.0 1.8 1 0 0 1 1 1 1 Threonine synthase N terminus AAA_18 PF13238.6 KFP00050.1 - 9.5e-07 29.4 0.0 2.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain PALP PF00291.25 KFP00050.1 - 2.8e-06 27.0 0.0 6.5e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AAA PF00004.29 KFP00050.1 - 2.4e-05 24.8 0.0 0.00029 21.3 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KFP00050.1 - 8.6e-05 22.0 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KFP00050.1 - 0.0017 18.5 0.0 0.0082 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KFP00050.1 - 0.0026 18.2 0.4 0.03 14.7 0.1 3.0 4 1 0 4 4 3 1 AAA domain RuvB_N PF05496.12 KFP00050.1 - 0.0028 17.4 0.0 0.0069 16.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFP00050.1 - 0.031 14.5 0.1 0.092 13.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain Cytidylate_kin PF02224.18 KFP00050.1 - 0.037 13.8 0.0 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase Acid_PPase PF12689.7 KFP00050.1 - 0.04 13.8 0.0 0.096 12.5 0.0 1.6 1 0 0 1 1 1 0 Acid Phosphatase Zeta_toxin PF06414.12 KFP00050.1 - 0.046 13.0 0.0 0.092 12.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Rad17 PF03215.15 KFP00050.1 - 0.048 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain IstB_IS21 PF01695.17 KFP00050.1 - 0.054 13.2 0.2 0.19 11.5 0.1 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein ADK PF00406.22 KFP00050.1 - 0.1 12.7 0.1 4.7 7.3 0.0 2.5 2 0 0 2 2 2 0 Adenylate kinase TsaE PF02367.17 KFP00050.1 - 0.16 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE 7tm_3 PF00003.22 KFP00051.1 - 2.2e-34 119.3 22.6 3.1e-34 118.7 22.6 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Myosin_head PF00063.21 KFP00052.1 - 6.1e-204 679.1 5.4 9.5e-204 678.4 5.4 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Pkinase PF00069.25 KFP00052.1 - 1.5e-60 204.8 0.0 2.9e-60 203.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP00052.1 - 8.1e-44 149.8 0.0 1.7e-43 148.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase IQ PF00612.27 KFP00052.1 - 1.2e-23 80.6 21.0 5.6e-05 22.6 0.1 5.8 5 0 0 5 5 5 5 IQ calmodulin-binding motif Kinase-like PF14531.6 KFP00052.1 - 0.00043 19.7 0.2 0.0018 17.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFP00052.1 - 0.00098 19.1 0.0 1.1 9.1 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family AAA_22 PF13401.6 KFP00052.1 - 0.0034 17.7 0.1 0.021 15.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Pyridoxal_deC PF00282.19 KFP00053.1 - 3.7e-136 453.7 0.0 4.4e-136 453.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KFP00053.1 - 4.9e-05 22.4 0.0 0.0003 19.9 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFP00053.1 - 0.001 18.5 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase TNFR_c6 PF00020.18 KFP00054.1 - 1.2e-06 28.8 10.3 2.7e-06 27.7 10.3 1.6 1 0 0 1 1 1 1 TNFR/NGFR cysteine-rich region EGF_CA PF07645.15 KFP00054.1 - 0.012 15.8 0.6 0.012 15.8 0.6 2.7 2 1 0 2 2 2 0 Calcium-binding EGF domain Aspzincin_M35 PF14521.6 KFP00054.1 - 0.05 14.1 1.3 0.06 13.9 1.3 1.1 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase RA PF00788.23 KFP00055.1 - 3.2e-14 53.3 2.2 1.3e-13 51.4 1.0 2.3 1 1 1 2 2 2 1 Ras association (RalGDS/AF-6) domain PH PF00169.29 KFP00055.1 - 1.3e-12 48.1 0.2 3e-12 46.9 0.2 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFP00055.1 - 0.0011 19.3 0.2 0.004 17.5 0.2 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain CAP_N PF01213.19 KFP00055.1 - 0.0027 17.2 2.4 0.0027 17.2 2.4 4.4 2 1 1 3 3 3 1 Adenylate cyclase associated (CAP) N terminal UPF0061 PF02696.14 KFP00056.1 - 2.1e-90 303.8 0.0 2.5e-90 303.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family polyprenyl_synt PF00348.17 KFP00057.1 - 5.3e-71 238.7 0.0 6.7e-71 238.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 KFP00057.1 - 0.00092 18.9 0.1 0.0017 18.0 0.1 1.3 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Abi_HHR PF07815.14 KFP00058.1 - 1.3e-35 121.4 0.6 2.6e-35 120.4 0.6 1.5 1 0 0 1 1 1 1 Abl-interactor HHR SH3_1 PF00018.28 KFP00058.1 - 3.7e-09 36.0 0.6 6.2e-09 35.3 0.6 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP00058.1 - 3.5e-06 26.8 0.1 9e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KFP00058.1 - 0.043 13.5 0.1 0.07 12.8 0.1 1.4 1 0 0 1 1 1 0 Variant SH3 domain ATP-synt_ab_Xtn PF16886.5 KFP00058.1 - 0.092 12.6 0.0 0.64 9.9 0.0 2.0 2 0 0 2 2 2 0 ATPsynthase alpha/beta subunit N-term extension Acid_PPase PF12689.7 KFP00058.1 - 0.21 11.4 0.2 0.36 10.7 0.2 1.3 1 0 0 1 1 1 0 Acid Phosphatase ACBP PF00887.19 KFP00059.1 - 5.1e-23 81.1 0.1 1.1e-22 80.0 0.1 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Pkinase PF00069.25 KFP00060.1 - 1.2e-50 172.3 0.1 1.8e-30 106.2 0.9 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFP00060.1 - 2e-25 89.6 0.2 3.5e-18 65.8 1.3 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KFP00060.1 - 0.0012 17.8 0.1 0.0012 17.8 0.1 2.1 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KFP00060.1 - 0.0018 18.3 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFP00060.1 - 0.007 15.7 0.4 0.014 14.8 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFP00060.1 - 0.008 15.5 0.0 0.028 13.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KFP00060.1 - 0.075 12.6 0.2 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Peptidase_M41 PF01434.18 KFP00061.1 - 4.7e-65 219.0 2.2 9.2e-65 218.1 2.2 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KFP00061.1 - 2.5e-41 141.2 0.0 7.9e-41 139.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFP00061.1 - 3.3e-08 33.2 0.2 7.8e-08 32.0 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KFP00061.1 - 4e-05 24.1 0.0 0.00069 20.0 0.0 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KFP00061.1 - 0.00025 21.1 0.0 0.001 19.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KFP00061.1 - 0.00027 20.2 0.2 0.00096 18.4 0.0 2.0 2 0 0 2 2 2 1 TIP49 P-loop domain RuvB_N PF05496.12 KFP00061.1 - 0.00039 20.2 0.0 0.00087 19.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFP00061.1 - 0.00057 20.2 0.0 0.019 15.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain DEDD_Tnp_IS110 PF01548.17 KFP00061.1 - 0.00094 19.1 0.1 0.98 9.3 0.1 3.1 3 0 0 3 3 3 1 Transposase IstB_IS21 PF01695.17 KFP00061.1 - 0.0062 16.3 0.0 0.022 14.5 0.0 2.0 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KFP00061.1 - 0.011 15.1 0.3 0.039 13.3 0.3 1.9 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 KFP00061.1 - 0.018 15.1 0.0 0.051 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KFP00061.1 - 0.018 15.2 0.0 0.043 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KFP00061.1 - 0.026 13.7 0.0 0.068 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 KFP00061.1 - 0.037 14.6 0.1 0.18 12.4 0.0 2.2 2 1 0 2 2 1 0 AAA domain AAA_17 PF13207.6 KFP00061.1 - 0.042 14.3 0.0 0.34 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain FumaraseC_C PF10415.9 KFP00061.1 - 0.047 14.1 4.0 0.24 11.9 1.6 3.2 3 0 0 3 3 3 0 Fumarase C C-terminus Zeta_toxin PF06414.12 KFP00061.1 - 0.081 12.2 0.0 0.24 10.7 0.0 1.9 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 KFP00061.1 - 0.12 11.9 0.1 0.46 10.0 0.1 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KFP00061.1 - 0.15 12.3 0.2 0.51 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KFP00061.1 - 0.21 11.1 0.3 1 8.9 0.3 2.0 1 1 1 2 2 2 0 AAA domain Patched PF02460.18 KFP00062.1 - 2.8e-171 571.5 5.5 3.4e-171 571.2 5.5 1.1 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 KFP00062.1 - 1e-36 126.1 4.5 1e-36 126.1 4.5 2.5 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 KFP00062.1 - 5.4 5.9 16.8 0.0081 15.1 3.0 2.3 2 0 0 2 2 2 0 MMPL family SecD_SecF PF02355.16 KFP00062.1 - 9.6 5.5 22.8 2 7.8 5.0 2.5 2 1 0 2 2 2 0 Protein export membrane protein KR PF08659.10 KFP00063.1 - 8.7e-53 178.9 0.0 2.4e-52 177.5 0.0 1.8 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KFP00063.1 - 1.2e-45 156.4 0.1 2.1e-45 155.6 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFP00063.1 - 8.8e-34 116.0 0.4 2.6e-33 114.6 0.4 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KFP00063.1 - 1.3e-28 100.2 0.0 2.5e-28 99.2 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KFP00063.1 - 6.9e-15 55.5 0.0 1.6e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KFP00063.1 - 3.3e-11 43.0 0.0 1.8e-10 40.6 0.1 2.3 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP00063.1 - 9.9e-06 25.3 0.0 2.7e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Homeobox_KN PF05920.11 KFP00064.1 - 1.3e-14 53.8 0.3 2.6e-14 52.8 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFP00064.1 - 3.1e-05 23.7 0.5 8.4e-05 22.3 0.5 1.8 1 0 0 1 1 1 1 Homeodomain Arm PF00514.23 KFP00065.1 - 3.8e-61 201.4 18.5 5e-05 23.2 0.1 13.4 13 0 0 13 13 13 12 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KFP00065.1 - 1.7e-21 76.4 1.5 3.7e-05 24.0 0.0 7.9 3 3 5 9 9 9 5 HEAT repeats HEAT_EZ PF13513.6 KFP00065.1 - 4.8e-10 39.7 5.2 0.00082 19.8 0.0 7.6 9 1 1 10 10 9 2 HEAT-like repeat HEAT PF02985.22 KFP00065.1 - 1.4e-09 37.3 12.0 0.74 10.2 0.1 8.0 8 0 0 8 8 7 3 HEAT repeat Adaptin_N PF01602.20 KFP00065.1 - 3.8e-09 35.7 1.9 8.4e-07 27.9 0.1 3.1 1 1 2 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.7 KFP00065.1 - 1.1e-07 32.0 1.6 0.011 15.8 0.1 4.7 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 KFP00065.1 - 2.3e-06 27.7 8.2 3.6 7.7 1.0 7.0 5 3 4 9 9 9 2 V-ATPase subunit H WAPL PF07814.13 KFP00065.1 - 5.5e-06 25.4 5.8 0.26 10.0 0.1 5.2 3 1 1 5 5 5 2 Wings apart-like protein regulation of heterochromatin KAP PF05804.12 KFP00065.1 - 1.9e-05 23.1 0.0 0.097 10.8 0.0 3.4 3 1 0 3 3 3 2 Kinesin-associated protein (KAP) UNC45-central PF11701.8 KFP00065.1 - 5.2e-05 23.3 8.6 0.43 10.5 0.1 4.6 3 1 1 4 4 4 3 Myosin-binding striated muscle assembly central Arm_2 PF04826.13 KFP00065.1 - 7.7e-05 22.3 1.9 9.2 5.6 0.0 6.2 3 2 3 6 6 6 1 Armadillo-like RasGEF_N_2 PF14663.6 KFP00065.1 - 0.0005 20.4 4.1 15 6.0 0.0 5.9 6 1 1 7 7 6 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Proteasom_PSMB PF10508.9 KFP00065.1 - 0.0013 17.3 0.6 0.14 10.7 0.0 3.2 3 0 0 3 3 3 1 Proteasome non-ATPase 26S subunit RICTOR_N PF14664.6 KFP00065.1 - 0.031 13.3 4.1 1.7 7.5 0.0 3.9 2 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term V-ATPase_H_N PF03224.14 KFP00065.1 - 0.034 13.4 0.5 31 3.7 0.0 3.8 4 0 0 4 4 4 0 V-ATPase subunit H RTTN_N PF14726.6 KFP00065.1 - 0.058 14.2 2.3 33 5.4 0.0 4.4 5 0 0 5 5 4 0 Rotatin, an armadillo repeat protein, centriole functioning Guanylate_kin PF00625.21 KFP00066.1 - 5.1e-50 169.7 0.3 1.5e-48 164.9 0.3 2.3 1 1 0 1 1 1 1 Guanylate kinase L27 PF02828.16 KFP00066.1 - 3.2e-26 90.8 8.6 3e-13 49.3 2.5 2.5 2 0 0 2 2 2 2 L27 domain PDZ PF00595.24 KFP00066.1 - 2.3e-12 47.1 0.8 6e-12 45.8 0.8 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP00066.1 - 6.9e-10 38.6 0.2 4.7e-09 36.0 0.2 2.3 2 0 0 2 2 2 1 PDZ domain SH3_2 PF07653.17 KFP00066.1 - 7.9e-08 31.9 0.0 2e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP00066.1 - 3.2e-07 29.9 0.3 2.6e-06 26.9 0.2 2.5 2 1 0 2 2 2 1 SH3 domain PDZ_2 PF13180.6 KFP00066.1 - 8.8e-05 22.8 0.1 0.00036 20.8 0.1 2.1 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.6 KFP00066.1 - 0.01 15.7 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain ADIP PF11559.8 KFP00067.1 - 0.00028 21.0 6.3 0.00034 20.7 6.3 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Filament PF00038.21 KFP00067.1 - 0.0006 19.5 5.1 0.00074 19.2 5.1 1.1 1 0 0 1 1 1 1 Intermediate filament protein Tropomyosin PF00261.20 KFP00067.1 - 0.00066 19.1 6.3 0.00082 18.8 6.3 1.1 1 0 0 1 1 1 1 Tropomyosin DUF2968 PF11180.8 KFP00067.1 - 0.0017 18.0 4.3 0.002 17.8 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) MAP65_ASE1 PF03999.12 KFP00067.1 - 0.0023 16.7 4.7 0.0025 16.6 4.7 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) APG6_N PF17675.1 KFP00067.1 - 0.0047 17.4 12.0 0.0071 16.9 12.0 1.4 1 1 0 1 1 1 1 Apg6 coiled-coil region HMMR_N PF15905.5 KFP00067.1 - 0.006 16.1 12.2 0.0064 16.0 12.2 1.0 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal PI3K_P85_iSH2 PF16454.5 KFP00067.1 - 0.01 15.4 5.8 0.014 15.0 5.8 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF3523 PF12037.8 KFP00067.1 - 0.011 15.1 5.4 0.013 14.9 5.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) TACC_C PF05010.14 KFP00067.1 - 0.012 15.5 8.4 0.15 11.8 5.0 2.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Cortex-I_coil PF09304.10 KFP00067.1 - 0.013 15.7 4.7 0.014 15.6 4.7 1.2 1 0 0 1 1 1 0 Cortexillin I, coiled coil Jnk-SapK_ap_N PF09744.9 KFP00067.1 - 0.014 15.6 6.8 0.016 15.4 6.8 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Prefoldin_3 PF13758.6 KFP00067.1 - 0.017 15.2 2.1 0.025 14.6 2.0 1.4 1 1 0 1 1 1 0 Prefoldin subunit DUF3450 PF11932.8 KFP00067.1 - 0.018 14.4 6.3 0.022 14.1 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CRIC_ras_sig PF10534.9 KFP00067.1 - 0.022 14.9 0.6 0.022 14.9 0.6 2.0 1 1 1 2 2 2 0 Connector enhancer of kinase suppressor of ras Bacillus_HBL PF05791.11 KFP00067.1 - 0.023 14.5 3.6 0.035 13.9 3.6 1.4 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF3086 PF11285.8 KFP00067.1 - 0.024 13.8 0.6 0.028 13.5 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) DivIVA PF05103.13 KFP00067.1 - 0.025 14.6 7.0 0.033 14.3 7.0 1.2 1 0 0 1 1 1 0 DivIVA protein HemX PF04375.14 KFP00067.1 - 0.027 13.8 5.8 0.03 13.6 5.8 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase BRE PF06113.12 KFP00067.1 - 0.028 13.3 0.9 0.029 13.2 0.9 1.1 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) Nup88 PF10168.9 KFP00067.1 - 0.028 12.2 6.9 0.034 12.0 6.9 1.0 1 0 0 1 1 1 0 Nuclear pore component DUF812 PF05667.11 KFP00067.1 - 0.038 12.9 7.2 0.044 12.7 7.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) GAS PF13851.6 KFP00067.1 - 0.047 13.0 12.0 0.3 10.4 11.9 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 KFP00067.1 - 0.05 13.7 8.1 0.055 13.6 8.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Herpes_UL6 PF01763.16 KFP00067.1 - 0.053 12.0 3.7 0.06 11.9 3.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF4140 PF13600.6 KFP00067.1 - 0.059 13.8 0.6 0.059 13.8 0.6 1.6 2 0 0 2 2 1 0 N-terminal domain of unknown function (DUF4140) SseC PF04888.12 KFP00067.1 - 0.059 13.0 4.0 0.07 12.7 4.0 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Spc7 PF08317.11 KFP00067.1 - 0.061 12.2 11.3 0.18 10.7 11.3 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KFP00067.1 - 0.069 13.2 11.1 0.23 11.5 10.4 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Cob_adeno_trans PF01923.18 KFP00067.1 - 0.081 13.1 2.0 0.1 12.7 1.9 1.3 1 1 0 1 1 1 0 Cobalamin adenosyltransferase JIP_LZII PF16471.5 KFP00067.1 - 0.084 13.1 8.9 0.053 13.7 5.4 2.2 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II HALZ PF02183.18 KFP00067.1 - 0.099 12.9 9.0 3.5 7.9 6.2 3.3 2 1 1 3 3 3 0 Homeobox associated leucine zipper DUF4047 PF13256.6 KFP00067.1 - 0.11 12.7 3.5 0.14 12.4 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) DUF724 PF05266.14 KFP00067.1 - 0.11 12.3 4.7 0.13 12.0 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) YabA PF06156.13 KFP00067.1 - 0.12 13.1 7.3 0.17 12.5 7.3 1.4 1 1 0 1 1 1 0 Initiation control protein YabA CHDCT2 PF08074.11 KFP00067.1 - 0.16 12.2 3.0 0.19 11.9 3.0 1.0 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Seryl_tRNA_N PF02403.22 KFP00067.1 - 0.16 12.2 8.0 0.59 10.4 7.3 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4600 PF15372.6 KFP00067.1 - 0.16 12.4 8.1 0.62 10.5 6.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) TMPIT PF07851.13 KFP00067.1 - 0.17 11.1 5.0 0.18 11.0 5.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 KFP00067.1 - 0.18 11.1 2.7 0.22 10.9 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fungal_TACC PF12709.7 KFP00067.1 - 0.19 12.2 7.8 0.66 10.5 5.1 2.6 1 1 2 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins CENP-F_leu_zip PF10473.9 KFP00067.1 - 0.23 11.5 13.3 0.37 10.8 13.3 1.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rho_Binding PF08912.11 KFP00067.1 - 0.24 12.2 10.2 3.4 8.6 2.2 2.3 1 1 1 2 2 2 0 Rho Binding ZapB PF06005.12 KFP00067.1 - 0.24 11.8 12.1 0.45 11.0 11.3 1.9 1 1 1 2 2 1 0 Cell division protein ZapB JAKMIP_CC3 PF16034.5 KFP00067.1 - 0.25 11.3 9.4 0.29 11.1 8.9 1.4 1 1 0 1 1 1 0 JAKMIP CC3 domain DUF5320 PF17253.2 KFP00067.1 - 0.27 12.3 1.9 0.52 11.4 1.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5320) CREPT PF16566.5 KFP00067.1 - 0.28 11.4 7.9 0.42 10.8 7.3 1.4 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Spore_III_AB PF09548.10 KFP00067.1 - 0.31 11.1 7.0 1.4 9.0 6.4 1.9 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF1664 PF07889.12 KFP00067.1 - 0.42 10.7 4.7 0.58 10.2 4.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FapA PF03961.13 KFP00067.1 - 0.58 8.7 5.6 0.63 8.6 5.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A SlyX PF04102.12 KFP00067.1 - 0.75 10.5 7.7 2.1 9.1 7.1 2.0 1 1 1 2 2 2 0 SlyX DUF16 PF01519.16 KFP00067.1 - 1 9.9 6.8 1.4 9.4 6.8 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 Spc24 PF08286.11 KFP00067.1 - 1.1 9.5 8.3 2 8.7 8.3 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DivIC PF04977.15 KFP00067.1 - 9.5 6.1 11.6 14 5.5 9.3 2.5 1 1 1 2 2 2 0 Septum formation initiator WW PF00397.26 KFP00068.1 - 1.4e-09 37.9 1.1 3e-09 36.8 1.1 1.5 1 0 0 1 1 1 1 WW domain BAMBI PF06211.12 KFP00069.1 - 3.9e-46 155.7 11.6 3.9e-46 155.7 11.6 1.6 2 0 0 2 2 2 1 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain LapA_dom PF06305.11 KFP00069.1 - 0.052 13.4 0.9 0.079 12.8 0.9 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain JIP_LZII PF16471.5 KFP00069.1 - 0.071 13.3 0.4 14 5.9 0.0 2.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II EphA2_TM PF14575.6 KFP00069.1 - 0.075 13.9 0.0 0.18 12.7 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SIT PF15330.6 KFP00069.1 - 0.21 12.0 0.9 11 6.6 0.0 2.7 3 0 0 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT KASH PF10541.9 KFP00069.1 - 0.96 9.8 3.9 6.6 7.1 0.2 2.5 2 0 0 2 2 2 0 Nuclear envelope localisation domain NUFIP1 PF10453.9 KFP00070.1 - 3.1e-20 71.8 7.5 8e-20 70.4 7.5 1.8 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-C2H2_jaz PF12171.8 KFP00070.1 - 0.00024 21.3 2.5 0.00064 19.9 2.5 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KFP00070.1 - 0.071 14.0 1.5 5.8 8.0 0.2 2.9 1 1 1 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP00070.1 - 3.9 8.1 6.3 0.44 11.1 1.6 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF3752 PF12572.8 KFP00071.1 - 9.9e-25 87.8 19.3 9.9e-25 87.8 19.3 2.5 2 1 0 3 3 3 1 Protein of unknown function (DUF3752) DUF4065 PF13274.6 KFP00071.1 - 3.1 8.7 8.2 12 6.9 2.2 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF4065) TFIIF_beta PF02270.15 KFP00072.1 - 8.4e-28 96.3 1.0 1.2e-27 95.8 0.2 1.7 2 0 0 2 2 2 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 KFP00072.1 - 4.5e-14 53.3 0.1 4.4e-13 50.1 0.0 2.3 2 1 0 2 2 2 1 TFIIF, beta subunit N-terminus BTB_2 PF02214.22 KFP00073.1 - 2.5e-18 66.2 0.0 6.2e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KFP00073.1 - 0.0084 16.2 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain TCTP PF00838.17 KFP00075.1 - 3.5e-59 199.9 0.2 3.9e-59 199.7 0.2 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Endotoxin_N PF03945.14 KFP00075.1 - 0.011 15.5 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain Mito_carr PF00153.27 KFP00076.1 - 4.2e-46 154.8 0.2 1.8e-23 82.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sec34 PF04136.15 KFP00077.1 - 1.8e-55 186.9 16.7 2.6e-55 186.4 6.1 4.1 4 0 0 4 4 4 1 Sec34-like family IL5 PF02025.15 KFP00077.1 - 0.038 14.3 2.2 14 6.0 0.0 4.2 4 0 0 4 4 4 0 Interleukin 5 CLTH PF10607.9 KFP00077.1 - 0.043 13.7 6.9 0.047 13.6 1.6 3.1 2 1 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain PP2C_C PF07830.13 KFP00077.1 - 0.094 13.2 1.6 0.75 10.3 0.1 3.0 2 1 1 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain CHASE3 PF05227.13 KFP00077.1 - 0.45 10.4 9.1 6.9 6.6 0.1 4.3 5 1 0 5 5 5 0 CHASE3 domain DUF948 PF06103.11 KFP00077.1 - 0.49 10.7 5.9 28 5.1 0.1 5.0 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Laminin_I PF06008.14 KFP00077.1 - 0.82 9.3 9.5 0.047 13.4 0.8 3.2 3 1 0 3 3 3 0 Laminin Domain I NPV_P10 PF05531.12 KFP00077.1 - 0.92 10.0 4.4 11 6.6 0.2 4.0 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein MAP70 PF07058.11 KFP00078.1 - 0.036 12.8 1.8 0.044 12.5 1.8 1.0 1 0 0 1 1 1 0 Microtubule-associated protein 70 GPHR_N PF12537.8 KFP00078.1 - 0.14 12.2 0.0 0.23 11.6 0.0 1.5 1 1 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal Chibby PF14645.6 KFP00079.1 - 2.9e-05 24.5 0.1 2.9e-05 24.5 0.1 2.9 2 2 1 3 3 3 1 Chibby family Med22 PF06179.12 KFP00079.1 - 0.029 14.6 1.6 0.052 13.8 0.9 1.9 1 1 1 2 2 2 0 Surfeit locus protein 5 subunit 22 of Mediator complex Stomoxyn PF11585.8 KFP00079.1 - 0.18 11.9 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn PRKG1_interact PF15898.5 KFP00079.1 - 2.1 9.3 11.9 2.8 8.9 0.1 3.3 3 1 0 3 3 3 0 cGMP-dependent protein kinase interacting domain Peptidase_M14 PF00246.24 KFP00080.1 - 4.5e-90 302.4 0.0 5.4e-90 302.1 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KFP00080.1 - 1.1e-07 32.1 0.6 2.6e-07 31.0 0.6 1.7 1 0 0 1 1 1 1 Carboxypeptidase activation peptide CH PF00307.31 KFP00081.1 - 4e-90 297.3 1.1 1.9e-24 85.9 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 KFP00081.1 - 5.3e-11 42.8 0.0 2.1e-10 40.9 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP00081.1 - 2.7e-09 35.9 0.5 0.00011 21.5 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFP00081.1 - 9.1e-09 34.6 0.6 8.7e-05 22.2 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain CAMSAP_CH PF11971.8 KFP00081.1 - 1.1e-06 28.4 0.1 7.9e-06 25.6 0.0 2.5 3 0 0 3 3 3 1 CAMSAP CH domain EF-hand_8 PF13833.6 KFP00081.1 - 0.00032 20.5 0.0 0.0016 18.3 0.0 2.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KFP00081.1 - 0.00033 20.0 1.0 0.21 11.2 0.2 2.7 2 0 0 2 2 2 2 EF hand LRR_8 PF13855.6 KFP00083.1 - 1.3e-23 82.5 10.4 2.3e-10 40.1 1.4 3.7 1 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFP00083.1 - 2.2e-16 59.7 15.3 0.0014 19.0 0.1 5.6 2 1 2 5 5 5 5 Leucine Rich repeats (2 copies) CH PF00307.31 KFP00083.1 - 4.2e-11 43.0 0.0 1.1e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain LRR_1 PF00560.33 KFP00083.1 - 2.6e-06 27.2 14.7 1.4 9.7 0.5 6.8 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.6 KFP00083.1 - 0.00084 19.2 10.3 1.5 9.1 0.5 5.2 5 0 0 5 5 5 2 Leucine Rich repeat CAMSAP_CH PF11971.8 KFP00083.1 - 0.0045 16.8 0.0 0.014 15.2 0.0 1.9 1 0 0 1 1 1 1 CAMSAP CH domain 7tm_1 PF00001.21 KFP00085.1 - 1.1e-67 228.2 13.5 1.4e-67 227.8 13.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP00085.1 - 4.8e-15 55.6 17.8 7.4e-15 55.0 17.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP00085.1 - 1.7e-07 31.3 8.8 1.7e-07 31.3 8.8 1.9 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP00085.1 - 2.5e-06 27.3 15.0 2.5e-06 27.3 15.0 2.4 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx ATP-grasp_2 PF08442.10 KFP00086.1 - 3.6e-75 252.0 1.5 6.5e-75 251.1 0.2 2.0 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KFP00086.1 - 1.9e-27 96.0 2.4 4.2e-27 94.8 2.4 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KFP00086.1 - 1.1e-09 38.1 0.4 2.5e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 KFP00086.1 - 0.027 14.3 0.8 0.073 12.8 0.8 1.7 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain nsp7 PF08716.10 KFP00086.1 - 0.11 13.1 1.1 2.8 8.6 0.2 2.6 2 0 0 2 2 2 0 nsp7 replicase NUDIX PF00293.28 KFP00087.1 - 0.0038 17.3 0.7 0.01 15.8 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain Med4 PF10018.9 KFP00088.1 - 2.2e-31 109.0 0.2 3.3e-31 108.5 0.2 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 HMMR_N PF15905.5 KFP00088.1 - 0.00011 21.8 6.5 0.00015 21.3 6.5 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Mu-like_Pro PF10123.9 KFP00088.1 - 0.0074 15.9 0.9 0.01 15.4 0.9 1.1 1 0 0 1 1 1 1 Mu-like prophage I protein Csm1_N PF18504.1 KFP00088.1 - 0.06 13.7 5.9 0.16 12.4 5.9 1.8 1 1 0 1 1 1 0 Csm1 N-terminal domain Trans_reg_C PF00486.28 KFP00088.1 - 0.2 11.8 1.3 3.6 7.7 0.3 2.5 1 1 1 2 2 2 0 Transcriptional regulatory protein, C terminal DUF724 PF05266.14 KFP00088.1 - 0.29 11.0 5.4 0.42 10.4 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FAM76 PF16046.5 KFP00088.1 - 0.29 10.5 4.0 0.39 10.0 4.0 1.1 1 0 0 1 1 1 0 FAM76 protein BRICHOS PF04089.14 KFP00089.1 - 4e-20 71.8 0.0 7.6e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 BRICHOS domain Antiterm PF03589.13 KFP00089.1 - 0.063 13.6 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Antitermination protein Rb_C PF08934.10 KFP00090.1 - 5.1e-82 273.1 3.2 5.1e-82 273.1 3.2 2.2 2 0 0 2 2 2 1 Rb C-terminal domain RB_A PF01858.17 KFP00090.1 - 2.8e-75 252.5 2.8 7.2e-75 251.2 0.6 2.5 2 0 0 2 2 2 1 Retinoblastoma-associated protein A domain RB_B PF01857.20 KFP00090.1 - 4.4e-31 107.6 11.6 1.1e-30 106.4 6.6 2.7 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 KFP00090.1 - 5.3e-14 52.0 2.7 5.3e-14 52.0 2.7 3.9 5 0 0 5 5 5 2 Domain of unknown function (DUF3452) 7tm_1 PF00001.21 KFP00091.1 - 3.2e-54 184.0 32.2 4e-54 183.7 32.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP00091.1 - 0.00075 19.2 32.5 0.00075 19.2 32.5 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx RCC1 PF00415.18 KFP00092.1 - 5e-62 206.3 23.0 1.5e-15 57.5 1.2 6.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFP00092.1 - 5.2e-32 109.0 25.3 2.9e-11 42.9 1.2 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KFP00092.1 - 5.1e-20 71.8 0.8 4.8e-17 62.2 0.1 2.3 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.15 KFP00092.1 - 1.4e-06 28.4 1.6 0.00034 20.7 0.3 3.2 2 1 1 3 3 3 1 BTB And C-terminal Kelch DUF4213 PF13938.6 KFP00092.1 - 0.011 16.0 3.2 2.9 8.2 0.0 3.1 2 1 0 2 2 2 0 Putative heavy-metal chelation Hira PF07569.11 KFP00092.1 - 0.054 13.2 3.2 4.6 6.9 0.0 4.1 5 0 0 5 5 5 0 TUP1-like enhancer of split Phage_int_SAM_5 PF13102.6 KFP00092.1 - 0.15 12.4 0.8 1.1 9.6 0.1 2.3 1 1 0 2 2 2 0 Phage integrase SAM-like domain Kelch_5 PF13854.6 KFP00092.1 - 3 7.9 8.6 45 4.2 0.2 4.4 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.15 KFP00092.1 - 4.9 7.3 8.1 15 5.7 0.2 4.6 5 0 0 5 5 5 0 Kelch motif fn3 PF00041.21 KFP00094.1 - 2.1e-38 130.5 4.3 8.5e-12 45.3 0.0 5.0 4 1 0 4 4 4 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFP00094.1 - 2.8e-07 31.0 10.6 0.035 14.7 2.1 4.4 5 2 0 5 5 5 3 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 KFP00094.1 - 6.3e-05 23.3 0.0 1.2 9.6 0.0 3.3 3 0 0 3 3 3 2 Uncharacterised conserved protein (DUF2369) Interfer-bind PF09294.10 KFP00094.1 - 0.0012 19.1 1.2 0.084 13.2 0.2 3.1 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III 7tm_1 PF00001.21 KFP00095.1 - 2.3e-41 141.9 22.1 2.8e-41 141.6 22.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP00095.1 - 0.00077 18.9 22.6 0.0016 17.9 22.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP00095.1 - 0.0054 16.5 5.8 0.0054 16.5 5.8 1.8 2 0 0 2 2 2 1 Olfactory receptor Ig_3 PF13927.6 KFP00096.1 - 1.8e-76 252.8 1.3 6.5e-13 49.1 0.0 7.0 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 KFP00096.1 - 1.2e-72 240.0 0.0 2.5e-13 49.9 0.0 6.9 7 0 0 7 7 6 6 Immunoglobulin I-set domain fn3 PF00041.21 KFP00096.1 - 1.5e-62 208.0 16.0 8.7e-14 51.6 0.3 5.6 5 0 0 5 5 5 5 Fibronectin type III domain Ig_2 PF13895.6 KFP00096.1 - 7.2e-49 164.0 0.8 4.4e-08 33.3 0.0 6.5 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.25 KFP00096.1 - 2e-46 156.1 0.0 5.7e-08 32.8 0.0 6.8 6 0 0 6 6 6 6 Immunoglobulin domain Bravo_FIGEY PF13882.6 KFP00096.1 - 6.1e-27 94.8 6.8 1.5e-26 93.6 6.8 1.7 1 0 0 1 1 1 1 Bravo-like intracellular region V-set PF07686.17 KFP00096.1 - 2.4e-15 56.6 3.9 0.055 13.7 0.0 9.6 8 3 1 9 9 9 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP00096.1 - 2.7e-12 46.6 0.2 0.2 11.7 0.0 6.5 5 1 1 6 6 6 3 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFP00096.1 - 6.5e-11 41.6 0.8 0.2 11.2 0.0 5.9 6 0 0 6 6 6 3 Immunoglobulin domain Ig_5 PF16681.5 KFP00096.1 - 8.8e-08 32.5 0.1 0.15 12.5 0.0 5.4 6 1 0 6 6 5 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFP00096.1 - 2.6e-07 30.8 0.4 1.9 8.8 0.0 5.3 6 0 0 6 6 5 2 T-cell surface glycoprotein CD3 delta chain Pur_ac_phosph_N PF16656.5 KFP00096.1 - 5.3e-07 30.1 3.9 0.0047 17.5 0.1 5.6 4 1 0 4 4 4 1 Purple acid Phosphatase, N-terminal domain Ig_C17orf99 PF17736.1 KFP00096.1 - 0.0001 22.3 0.0 5 7.2 0.0 5.1 5 0 0 5 5 5 1 C17orf99 Ig domain BiPBP_C PF06832.12 KFP00096.1 - 0.00096 19.1 0.0 1.8 8.7 0.0 3.3 3 0 0 3 3 2 1 Penicillin-Binding Protein C-terminus Family Interfer-bind PF09294.10 KFP00096.1 - 0.0012 19.1 0.6 6.3 7.2 0.0 4.8 6 0 0 6 6 4 1 Interferon-alpha/beta receptor, fibronectin type III Adeno_E3_CR1 PF02440.15 KFP00096.1 - 0.0031 17.3 3.7 0.18 11.6 0.0 4.3 5 0 0 5 5 4 1 Adenovirus E3 region protein CR1 SIT PF15330.6 KFP00096.1 - 0.005 17.3 0.0 0.33 11.4 0.0 2.5 2 0 0 2 2 2 1 SHP2-interacting transmembrane adaptor protein, SIT Izumo-Ig PF16706.5 KFP00096.1 - 0.0052 16.8 0.1 4.1 7.5 0.0 3.7 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain V-set_CD47 PF08204.11 KFP00096.1 - 0.0059 16.6 3.0 9.7 6.2 0.0 3.8 4 0 0 4 4 4 0 CD47 immunoglobulin-like domain DUF5640 PF18692.1 KFP00096.1 - 0.051 13.6 0.3 11 6.1 0.0 4.0 3 0 0 3 3 3 0 Family of unknown function (DUF5640) INCA1 PF15142.6 KFP00096.1 - 0.16 12.0 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 INCA1 Ig_3 PF13927.6 KFP00097.1 - 4.1e-63 210.0 0.3 8.8e-12 45.5 0.0 7.2 7 0 0 7 7 6 6 Immunoglobulin domain I-set PF07679.16 KFP00097.1 - 3.3e-56 187.3 6.0 8.9e-12 44.9 0.0 8.3 6 3 1 7 7 7 6 Immunoglobulin I-set domain ig PF00047.25 KFP00097.1 - 1.2e-41 140.8 0.1 8e-10 38.8 0.0 7.4 5 2 1 6 6 6 6 Immunoglobulin domain Ig_2 PF13895.6 KFP00097.1 - 9.9e-39 131.6 0.2 2.4e-07 31.0 0.0 6.4 5 1 1 6 6 6 5 Immunoglobulin domain fn3 PF00041.21 KFP00097.1 - 9.1e-37 125.3 11.6 4.9e-17 62.1 1.7 4.8 4 0 0 4 4 4 4 Fibronectin type III domain V-set PF07686.17 KFP00097.1 - 1.5e-24 86.3 12.2 0.0051 17.0 0.1 10.4 8 4 1 9 9 8 5 Immunoglobulin V-set domain Ig_5 PF16681.5 KFP00097.1 - 2.3e-10 40.7 0.0 0.37 11.2 0.0 6.6 6 0 0 6 6 6 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFP00097.1 - 2.8e-10 39.6 0.3 0.51 9.9 0.0 6.0 6 0 0 6 6 6 3 Immunoglobulin domain Ig_4 PF16680.5 KFP00097.1 - 3.9e-08 33.4 0.0 0.92 9.8 0.0 5.0 5 0 0 5 5 5 3 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFP00097.1 - 4.2e-07 29.9 0.3 2.3 8.4 0.0 6.2 7 0 0 7 7 7 1 Izumo-like Immunoglobulin domain Adeno_E3_CR1 PF02440.15 KFP00097.1 - 5.9e-06 26.0 6.2 1.2 9.0 0.1 6.3 6 1 0 6 6 6 1 Adenovirus E3 region protein CR1 Pur_ac_phosph_N PF16656.5 KFP00097.1 - 2.9e-05 24.6 1.9 2.9e-05 24.6 1.9 3.4 3 1 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain Tissue_fac PF01108.17 KFP00097.1 - 0.0001 22.1 0.9 0.12 12.3 0.0 4.5 3 1 2 5 5 5 1 Tissue factor C2-set_2 PF08205.12 KFP00097.1 - 0.00029 20.8 0.0 1.8 8.7 0.0 3.5 4 0 0 4 4 3 2 CD80-like C2-set immunoglobulin domain Interfer-bind PF09294.10 KFP00097.1 - 0.001 19.4 0.1 0.0093 16.3 0.1 2.5 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III Ig_C17orf99 PF17736.1 KFP00097.1 - 0.0017 18.4 0.0 5.9 7.0 0.0 5.1 5 1 0 5 5 5 1 C17orf99 Ig domain CBM_35 PF16990.5 KFP00097.1 - 0.0056 16.9 0.2 0.099 12.9 0.0 3.1 3 1 0 3 3 2 1 Carbohydrate binding module (family 35) DUF4998 PF16389.5 KFP00097.1 - 0.0067 16.0 0.1 0.017 14.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function Big_3_4 PF13754.6 KFP00097.1 - 0.039 13.7 0.0 0.21 11.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF2369 PF10179.9 KFP00097.1 - 0.11 13.0 0.0 2.5 8.6 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) PKD PF00801.20 KFP00097.1 - 0.62 10.0 2.9 10 6.1 0.1 4.0 4 0 0 4 4 4 0 PKD domain Ndufs5 PF10200.9 KFP00098.1 - 5e-06 26.7 0.1 5.7e-06 26.5 0.1 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Orn_Arg_deC_N PF02784.16 KFP00099.1 - 1.9e-68 230.5 0.0 2.4e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KFP00099.1 - 2.3e-08 34.2 0.0 3.7e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain ADK PF00406.22 KFP00100.1 - 5.8e-52 175.8 0.0 6.9e-52 175.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.14 KFP00100.1 - 3.2e-16 59.0 0.0 7.9e-16 57.7 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 KFP00100.1 - 2.2e-15 57.3 0.0 4.6e-15 56.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain IBR PF01485.21 KFP00101.1 - 1.1e-20 73.6 46.6 6.5e-13 48.7 15.7 3.2 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KFP00101.1 - 0.008 16.0 4.9 0.008 16.0 4.9 4.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP00101.1 - 0.014 15.4 3.7 0.014 15.4 3.7 4.4 3 1 0 3 3 3 0 zinc-RING finger domain EF-hand_7 PF13499.6 KFP00102.1 - 3.1e-27 94.8 2.9 6.5e-18 65.0 0.1 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KFP00102.1 - 1.1e-26 90.4 6.2 3e-07 29.5 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFP00102.1 - 9.3e-24 81.3 1.2 5.5e-07 29.0 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KFP00102.1 - 3.2e-23 80.1 4.8 3.5e-07 29.4 0.2 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KFP00102.1 - 1.9e-19 69.2 4.3 6e-07 29.2 0.2 3.6 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFP00102.1 - 2.1e-07 31.3 0.2 0.0031 17.8 0.1 3.2 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFP00102.1 - 8e-07 29.0 0.8 0.27 11.2 0.0 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 KFP00102.1 - 0.00073 19.3 0.1 1.7 8.5 0.0 3.1 3 0 0 3 3 3 2 EF hand Dockerin_1 PF00404.18 KFP00102.1 - 0.005 17.0 0.3 5.9 7.2 0.2 2.9 2 1 0 2 2 2 2 Dockerin type I domain DUF832 PF05734.11 KFP00102.1 - 0.083 12.4 0.2 2.2 7.7 0.2 2.0 1 1 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) fn3 PF00041.21 KFP00103.1 - 2.8e-10 40.4 0.7 6.4e-10 39.2 0.1 1.9 2 0 0 2 2 2 1 Fibronectin type III domain DUF4808 PF16066.5 KFP00103.1 - 2.8e-07 31.1 0.0 2.3e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4808) Interfer-bind PF09294.10 KFP00103.1 - 0.23 11.8 0.0 0.23 11.8 0.0 2.0 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III tRNA-synt_1b PF00579.25 KFP00104.1 - 1.2e-75 254.6 0.0 1.5e-75 254.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA_bind PF01588.20 KFP00104.1 - 1.6e-32 111.5 0.1 3.8e-32 110.3 0.1 1.7 1 0 0 1 1 1 1 Putative tRNA binding domain Filament PF00038.21 KFP00108.1 - 3.6e-21 76.1 33.6 5.9e-21 75.4 33.6 1.4 1 1 0 1 1 1 1 Intermediate filament protein Spc7 PF08317.11 KFP00108.1 - 0.00024 20.1 34.4 0.002 17.1 14.1 2.3 1 1 1 2 2 2 2 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KFP00108.1 - 0.0017 18.4 32.9 0.01 15.9 6.6 4.4 2 2 1 3 3 3 2 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 KFP00108.1 - 0.0023 17.9 16.2 0.93 9.5 3.6 3.7 1 1 3 4 4 4 3 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.9 KFP00108.1 - 0.0033 17.7 18.1 0.0033 17.7 18.1 2.7 2 1 0 2 2 2 1 JNK_SAPK-associated protein-1 CENP-H PF05837.12 KFP00108.1 - 0.0045 17.4 10.1 0.0045 17.4 10.1 3.5 2 1 2 4 4 4 1 Centromere protein H (CENP-H) Prp19 PF08606.11 KFP00108.1 - 0.0074 16.3 2.8 0.0074 16.3 2.8 3.4 4 0 0 4 4 3 1 Prp19/Pso4-like Laminin_II PF06009.12 KFP00108.1 - 0.008 16.2 18.2 0.15 12.0 4.9 3.2 2 1 1 3 3 3 2 Laminin Domain II Zein-binding PF04576.15 KFP00108.1 - 0.017 15.4 3.4 0.017 15.4 3.4 3.5 3 1 1 4 4 2 0 Zein-binding Cob_adeno_trans PF01923.18 KFP00108.1 - 0.019 15.1 8.9 0.034 14.3 0.5 2.9 2 1 1 3 3 3 0 Cobalamin adenosyltransferase DUF948 PF06103.11 KFP00108.1 - 0.048 13.9 4.0 16 5.9 0.1 4.2 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.9 KFP00108.1 - 0.056 13.5 43.2 0.12 12.4 8.1 3.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0565 PF10561.9 KFP00108.1 - 0.18 11.0 0.1 0.18 11.0 0.1 1.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 bZIP_1 PF00170.21 KFP00108.1 - 0.21 11.7 26.3 5.4 7.2 0.3 5.7 5 1 1 6 6 6 0 bZIP transcription factor Fez1 PF06818.15 KFP00108.1 - 0.25 11.8 31.7 0.68 10.4 11.4 2.2 1 1 1 2 2 2 0 Fez1 Peptidase_M26_C PF07580.14 KFP00108.1 - 0.25 9.8 3.1 0.097 11.1 0.3 1.6 2 0 0 2 2 2 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region Cauli_AT PF03233.13 KFP00108.1 - 0.4 10.6 9.8 0.66 9.9 1.1 2.6 3 0 0 3 3 2 0 Aphid transmission protein YabA PF06156.13 KFP00108.1 - 0.61 10.8 28.1 0.18 12.4 3.4 4.9 2 2 1 3 3 3 0 Initiation control protein YabA Prominin PF05478.11 KFP00108.1 - 0.7 7.8 16.8 0.082 10.9 6.4 2.2 1 1 1 2 2 2 0 Prominin TMPIT PF07851.13 KFP00108.1 - 0.81 8.9 18.3 0.13 11.5 2.8 3.0 2 1 1 3 3 3 0 TMPIT-like protein DUF4972 PF16342.5 KFP00108.1 - 0.81 9.4 5.8 0.45 10.2 0.5 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4972) UPF0242 PF06785.11 KFP00108.1 - 0.82 9.7 38.0 1.4 8.9 14.5 2.8 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Seryl_tRNA_N PF02403.22 KFP00108.1 - 0.84 9.9 26.3 1.3 9.2 7.8 3.6 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain BRE1 PF08647.11 KFP00108.1 - 0.89 9.7 25.6 1.4 9.1 7.7 3.7 2 1 2 4 4 4 0 BRE1 E3 ubiquitin ligase Golgin_A5 PF09787.9 KFP00108.1 - 0.97 8.8 37.6 0.31 10.4 8.1 2.9 1 1 2 3 3 3 0 Golgin subfamily A member 5 Bacillus_HBL PF05791.11 KFP00108.1 - 0.98 9.2 11.4 3.2 7.5 0.8 3.3 2 2 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) GAS PF13851.6 KFP00108.1 - 1.7 7.9 36.1 0.67 9.3 14.0 3.3 2 2 0 2 2 2 0 Growth-arrest specific micro-tubule binding THOC7 PF05615.13 KFP00108.1 - 1.9 8.8 31.4 2.5 8.4 7.0 3.4 2 1 1 3 3 3 0 Tho complex subunit 7 MAD PF05557.13 KFP00108.1 - 3.9 5.7 39.5 2.6 6.3 8.2 2.2 1 1 1 2 2 2 0 Mitotic checkpoint protein COG2 PF06148.11 KFP00108.1 - 4.1 7.5 20.0 13 5.9 5.4 4.0 2 2 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2937 PF11157.8 KFP00108.1 - 4.3 7.0 6.9 2.3 7.9 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) BST2 PF16716.5 KFP00108.1 - 4.6 7.9 32.0 3.5 8.3 6.6 4.2 2 2 2 4 4 4 0 Bone marrow stromal antigen 2 ATG16 PF08614.11 KFP00108.1 - 8.5 6.5 37.6 2.8 8.1 2.6 4.0 2 2 1 3 3 3 0 Autophagy protein 16 (ATG16) CAF1C_H4-bd PF12265.8 KFP00109.1 - 1.9e-28 98.5 0.5 3.4e-27 94.5 0.2 2.8 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KFP00109.1 - 7.4e-24 83.6 13.7 7.8e-07 29.7 0.0 5.7 4 1 1 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP00109.1 - 5.5e-05 23.4 0.8 0.01 16.2 0.1 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP00109.1 - 0.00028 20.8 0.4 0.058 13.3 0.0 3.1 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Capsid_NCLDV PF04451.12 KFP00109.1 - 0.082 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein Archease PF01951.16 KFP00110.1 - 2.8e-44 150.7 0.1 3.3e-44 150.5 0.1 1.1 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) BTB PF00651.31 KFP00111.1 - 6.3e-26 90.8 0.5 1.3e-25 89.8 0.5 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFP00111.1 - 6.5e-09 35.8 2.2 6.5e-09 35.8 2.2 3.8 3 0 0 3 3 3 1 Zinc-finger double domain DUF3342 PF11822.8 KFP00111.1 - 1.1e-05 25.6 0.1 2.4e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) zf-C2H2 PF00096.26 KFP00111.1 - 0.00028 21.2 1.6 0.00028 21.2 1.6 4.0 4 0 0 4 4 3 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFP00111.1 - 0.00083 19.1 3.6 0.00083 19.1 3.6 2.6 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KFP00111.1 - 0.0024 18.6 1.1 0.0024 18.6 1.1 4.2 4 0 0 4 4 3 2 C2H2-type zinc finger zf-met PF12874.7 KFP00111.1 - 0.0031 17.8 2.0 0.17 12.3 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger of C2H2 type Prim_Zn_Ribbon PF08273.12 KFP00111.1 - 0.022 15.0 0.5 0.022 15.0 0.5 2.2 2 0 0 2 2 1 0 Zinc-binding domain of primase-helicase zinc_ribbon_10 PF10058.9 KFP00111.1 - 0.03 14.0 3.2 4.6 7.1 1.7 2.8 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn-ribbon_8 PF09723.10 KFP00111.1 - 0.031 14.4 0.6 0.031 14.4 0.6 3.1 3 0 0 3 3 2 0 Zinc ribbon domain BTB_2 PF02214.22 KFP00111.1 - 0.032 14.6 0.7 0.078 13.3 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain zf-C2H2_jaz PF12171.8 KFP00111.1 - 0.069 13.5 1.4 1.9 8.9 0.1 3.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Trm112p PF03966.16 KFP00111.1 - 0.073 13.7 1.6 0.22 12.1 1.6 1.8 1 0 0 1 1 1 0 Trm112p-like protein DUF3212 PF11486.8 KFP00111.1 - 0.11 12.6 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3212) zf-Di19 PF05605.12 KFP00111.1 - 0.21 11.9 10.9 0.18 12.1 6.7 2.7 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PHF5 PF03660.14 KFP00111.1 - 0.32 11.2 6.4 5.7 7.2 0.8 2.8 1 1 0 2 2 2 0 PHF5-like protein Lar_restr_allev PF14354.6 KFP00111.1 - 0.89 10.0 8.9 1.8 9.0 2.9 3.3 2 1 0 2 2 2 0 Restriction alleviation protein Lar BTB PF00651.31 KFP00112.1 - 7.2e-27 93.8 0.3 1.1e-26 93.2 0.3 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFP00112.1 - 1.3e-08 34.9 2.4 1.3e-08 34.9 2.4 3.8 3 0 0 3 3 3 1 Zinc-finger double domain DUF3342 PF11822.8 KFP00112.1 - 4.2e-06 26.9 0.1 1.1e-05 25.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) zf-C2H2 PF00096.26 KFP00112.1 - 9.3e-05 22.7 24.3 0.00018 21.8 1.7 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFP00112.1 - 0.00022 20.9 2.9 0.00022 20.9 2.9 2.3 3 0 0 3 3 3 1 C2H2-type zinc-finger domain BTB_2 PF02214.22 KFP00112.1 - 0.001 19.4 0.0 0.002 18.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.6 KFP00112.1 - 0.0021 18.7 1.5 0.0021 18.7 1.5 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 KFP00112.1 - 0.015 15.7 2.4 0.17 12.3 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf_UBZ PF18439.1 KFP00112.1 - 6.2 6.5 6.4 3.4 7.3 0.1 3.4 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 KFP00112.1 - 8.5 6.8 13.3 0.43 10.9 6.5 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding BTB PF00651.31 KFP00113.1 - 4.1e-26 91.4 0.2 6.8e-26 90.7 0.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFP00113.1 - 4.4e-07 30.0 20.7 1.3e-05 25.4 0.6 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFP00113.1 - 1.4e-05 25.3 1.4 1.4e-05 25.3 1.4 4.4 5 0 0 5 5 5 1 Zinc finger, C2H2 type DUF3342 PF11822.8 KFP00113.1 - 1.8e-05 24.8 0.1 5.2e-05 23.4 0.0 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3342) zf-C2H2_4 PF13894.6 KFP00113.1 - 0.0045 17.7 1.4 0.0045 17.7 1.4 5.1 6 0 0 6 6 6 1 C2H2-type zinc finger zf-met PF12874.7 KFP00113.1 - 0.02 15.2 0.1 0.02 15.2 0.1 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Herpes_ori_bp PF02399.15 KFP00113.1 - 0.076 11.1 0.3 0.13 10.3 0.3 1.3 1 0 0 1 1 1 0 Origin of replication binding protein BSD PF03909.17 KFP00114.1 - 1.4e-18 66.6 2.4 2.4e-17 62.7 0.2 2.4 2 0 0 2 2 2 2 BSD domain Arm PF00514.23 KFP00115.1 - 4e-90 293.4 21.3 1.2e-13 50.5 0.0 9.0 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KFP00115.1 - 5.8e-25 87.6 1.8 5.8e-25 87.6 1.8 1.8 2 0 0 2 2 1 1 Importin beta binding domain Arm_3 PF16186.5 KFP00115.1 - 1e-22 79.4 3.0 2.1e-22 78.4 1.9 2.2 3 0 0 3 3 3 1 Atypical Arm repeat HEAT_2 PF13646.6 KFP00115.1 - 3.5e-21 75.4 0.0 2.5e-07 31.0 0.0 5.0 3 2 2 5 5 4 4 HEAT repeats HEAT_EZ PF13513.6 KFP00115.1 - 6.5e-21 74.4 6.1 7.2e-07 29.6 0.0 6.2 5 2 2 7 7 7 3 HEAT-like repeat HEAT PF02985.22 KFP00115.1 - 8.6e-14 50.5 8.3 0.0031 17.6 0.0 7.8 9 0 0 9 9 9 2 HEAT repeat V-ATPase_H_C PF11698.8 KFP00115.1 - 2.8e-06 27.4 0.0 0.19 11.9 0.0 4.3 3 2 1 4 4 4 1 V-ATPase subunit H RICTOR_V PF14668.6 KFP00115.1 - 3.6e-06 27.1 1.1 0.71 10.1 0.0 4.8 4 1 1 5 5 4 1 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.13 KFP00115.1 - 6.5e-06 25.8 0.0 0.1 12.0 0.0 2.8 1 1 1 2 2 2 2 Armadillo-like HEAT_PBS PF03130.16 KFP00115.1 - 0.00059 20.3 0.4 8.7 7.3 0.0 4.9 5 0 0 5 5 4 1 PBS lyase HEAT-like repeat CTNNBL PF08216.11 KFP00115.1 - 0.0082 16.3 0.0 1.9 8.7 0.0 3.9 4 0 0 4 4 4 1 Catenin-beta-like, Arm-motif containing nuclear SEN1_N PF12726.7 KFP00115.1 - 0.04 12.1 0.0 4.1 5.5 0.0 2.8 2 1 1 3 3 3 0 SEN1 N terminal NUSAP PF16006.5 KFP00115.1 - 1.5 8.5 6.1 2.1 8.0 6.1 1.2 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein PAH PF02671.21 KFP00115.1 - 6.2 7.0 5.6 1.4 9.2 0.7 2.5 2 1 1 3 3 3 0 Paired amphipathic helix repeat Taxilin PF09728.9 KFP00116.1 - 2.7e-118 394.6 78.7 3e-118 394.5 78.7 1.0 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Phage_GPL PF05926.11 KFP00116.1 - 1.2 9.2 12.2 0.12 12.4 3.2 2.9 2 2 0 2 2 2 0 Phage head completion protein (GPL) NDUFB11 PF17250.2 KFP00116.1 - 1.5 9.5 6.2 0.32 11.7 1.0 2.6 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase 11 kDa subunit DUF3450 PF11932.8 KFP00116.1 - 2.4 7.4 56.6 1.1 8.5 21.7 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) SpoVAD PF07451.11 KFP00116.1 - 6.2 5.4 7.3 8.7 4.9 0.7 2.3 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) HOOK PF05622.12 KFP00116.1 - 9.9 4.2 67.1 2.4 6.2 61.9 2.4 1 1 1 2 2 2 0 HOOK protein DUF4061 PF13270.6 KFP00117.1 - 2.6e-33 114.2 1.7 3.2e-33 113.9 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) IQ PF00612.27 KFP00118.1 - 0.038 13.8 0.5 0.038 13.8 0.5 2.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif DCX PF03607.17 KFP00119.1 - 1.2e-19 70.2 0.0 1.5e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 Doublecortin DCX PF03607.17 KFP00120.1 - 4.8e-14 52.2 0.0 6.5e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Doublecortin TMEM234 PF10639.9 KFP00121.1 - 4.3e-23 81.6 1.3 4.7e-23 81.4 1.3 1.0 1 0 0 1 1 1 1 Putative transmembrane family 234 WD40 PF00400.32 KFP00122.1 - 9.5e-27 92.7 1.6 1.3e-06 29.0 2.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP00122.1 - 2.2e-13 50.3 0.0 0.0043 17.3 0.0 5.0 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP00122.1 - 0.0012 17.8 1.1 0.61 9.0 0.1 3.1 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ISN1 PF06437.11 KFP00122.1 - 0.0039 16.2 0.1 0.57 9.0 0.1 2.1 2 0 0 2 2 2 2 IMP-specific 5'-nucleotidase Nup160 PF11715.8 KFP00122.1 - 0.029 13.0 0.3 1.7 7.2 0.1 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 FAM167 PF11652.8 KFP00123.1 - 7.5e-37 125.7 0.5 1.2e-36 125.1 0.5 1.3 1 0 0 1 1 1 1 FAM167 DUF2388 PF09498.10 KFP00123.1 - 0.00017 21.5 0.1 0.00032 20.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2388) DUF4164 PF13747.6 KFP00123.1 - 0.0053 17.0 1.6 0.0053 17.0 1.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4164) ATG16 PF08614.11 KFP00123.1 - 0.0094 16.2 0.1 0.013 15.8 0.1 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) LURAP PF14854.6 KFP00123.1 - 0.049 13.6 0.1 0.08 12.9 0.1 1.3 1 0 0 1 1 1 0 Leucine rich adaptor protein DUF4404 PF14357.6 KFP00123.1 - 0.77 10.4 4.2 0.16 12.6 1.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Pkinase_Tyr PF07714.17 KFP00124.1 - 1.4e-96 322.8 0.0 1.8e-96 322.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP00124.1 - 3.3e-50 170.9 0.0 4.2e-50 170.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFP00124.1 - 2.1e-27 95.0 0.5 3.8e-27 94.2 0.5 1.5 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFP00124.1 - 1.3e-14 53.5 0.1 3.1e-14 52.3 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP00124.1 - 4.1e-09 36.2 0.0 8.3e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP00124.1 - 8.1e-08 31.8 0.0 1.8e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Haspin_kinase PF12330.8 KFP00124.1 - 0.0032 16.5 0.0 0.0047 15.9 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain SH3_3 PF08239.11 KFP00124.1 - 0.064 13.6 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Kdo PF06293.14 KFP00124.1 - 0.17 11.2 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Hist_deacetyl PF00850.19 KFP00125.1 - 1.5e-85 287.4 0.1 2.3e-85 286.8 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Dehydrin PF00257.19 KFP00125.1 - 0.99 9.9 5.0 2.1 8.9 5.0 1.5 1 0 0 1 1 1 0 Dehydrin MARCKS PF02063.17 KFP00126.1 - 6.6e-17 62.4 40.7 2e-16 60.8 40.7 1.7 1 1 0 1 1 1 1 MARCKS family Tmp39 PF10271.9 KFP00127.1 - 1.7e-209 696.2 18.8 1.9e-209 696.0 18.8 1.0 1 0 0 1 1 1 1 Putative transmembrane protein Sam68-YY PF16568.5 KFP00128.1 - 1.3e-14 54.6 36.2 2.2e-14 53.9 36.2 1.4 1 0 0 1 1 1 1 Tyrosine-rich domain of Sam68 KH_1 PF00013.29 KFP00128.1 - 2.9e-11 43.0 0.0 5e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 KH domain Qua1 PF16274.5 KFP00128.1 - 1.3e-10 40.9 0.6 1.3e-10 40.9 0.6 1.9 2 0 0 2 2 2 1 Qua1 domain KH_5 PF13184.6 KFP00128.1 - 0.18 11.9 0.0 0.31 11.2 0.0 1.3 1 0 0 1 1 1 0 NusA-like KH domain DSPc PF00782.20 KFP00129.1 - 7.1e-08 32.3 0.0 1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP00129.1 - 2e-07 30.9 0.0 5.3e-07 29.4 0.0 1.6 1 1 1 2 2 2 1 Protein-tyrosine phosphatase 7tm_2 PF00002.24 KFP00131.1 - 3.3e-56 190.3 11.7 4e-56 190.1 11.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF1129 PF06570.11 KFP00131.1 - 0.085 12.3 3.5 0.059 12.8 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) 7tm_1 PF00001.21 KFP00131.1 - 0.13 11.6 8.7 0.21 10.9 8.5 1.3 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) EF-hand_1 PF00036.32 KFP00132.1 - 1.6e-18 64.8 0.5 1.7e-06 27.1 0.0 4.3 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KFP00132.1 - 3.1e-18 64.1 0.2 5.6e-07 29.0 0.0 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KFP00132.1 - 2.4e-17 61.5 1.5 1e-06 27.9 0.0 3.7 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 KFP00132.1 - 3.3e-16 59.5 0.3 2.2e-07 31.2 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFP00132.1 - 1.7e-08 34.2 0.1 0.012 15.5 0.0 4.1 3 1 1 4 4 4 3 EF-hand domain pair GUN4 PF05419.12 KFP00132.1 - 0.04 14.0 0.1 0.1 12.7 0.0 1.6 1 1 0 1 1 1 0 GUN4-like EF-hand_2 PF09068.11 KFP00132.1 - 0.045 13.9 0.0 2.3 8.4 0.0 2.8 1 1 3 4 4 4 0 EF hand Caleosin PF05042.13 KFP00132.1 - 0.061 13.2 0.0 0.26 11.2 0.0 1.9 1 1 1 2 2 2 0 Caleosin related protein Peptidase_C1 PF00112.23 KFP00133.1 - 2.7e-24 86.5 0.1 4.4e-24 85.8 0.1 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Pacifastin_I PF05375.13 KFP00133.1 - 2.7e-06 27.0 2.8 1.2e-05 24.9 2.8 2.2 1 0 0 1 1 1 1 Pacifastin inhibitor (LCMII) Somatomedin_B PF01033.17 KFP00133.1 - 0.0086 16.5 19.1 0.0086 16.5 19.1 2.5 2 1 0 2 2 2 1 Somatomedin B domain KCNQ_channel PF03520.14 KFP00134.1 - 1e-90 302.7 0.2 1.3e-90 302.4 0.2 1.1 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel Ion_trans_2 PF07885.16 KFP00135.1 - 2e-15 56.5 3.2 2.3e-15 56.3 3.2 1.1 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 KFP00135.1 - 2.8e-07 30.0 2.0 3.1e-07 29.9 2.0 1.1 1 0 0 1 1 1 1 Ion transport protein Lig_chan PF00060.26 KFP00135.1 - 0.016 15.0 3.8 0.055 13.3 3.8 1.7 1 1 0 1 1 1 0 Ligand-gated ion channel DUF2798 PF11391.8 KFP00135.1 - 0.044 13.8 3.8 0.39 10.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) CBFD_NFYB_HMF PF00808.23 KFP00136.1 - 1.1e-21 76.8 2.5 3.8e-21 75.1 1.6 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFP00136.1 - 1.5e-15 57.7 1.1 1.5e-15 57.7 1.1 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KFP00136.1 - 0.042 14.2 0.1 0.1 12.9 0.1 1.7 1 0 0 1 1 1 0 CENP-S associating Centromere protein X C2 PF00168.30 KFP00137.1 - 1.7e-16 60.4 0.0 2.9e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain ArfGap PF01412.18 KFP00138.1 - 8.4e-32 109.7 0.2 1.9e-31 108.5 0.2 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf CUB PF00431.20 KFP00139.1 - 1.1e-275 894.8 0.0 7.6e-26 90.6 0.0 12.3 12 0 0 12 12 12 12 CUB domain Sushi PF00084.20 KFP00139.1 - 3.8e-261 844.0 163.4 6.2e-13 49.1 1.0 27.4 27 0 0 27 27 27 27 Sushi repeat (SCR repeat) CUB_2 PF02408.20 KFP00139.1 - 2.2e-21 75.8 20.5 0.00019 21.2 0.6 11.1 12 0 0 12 12 12 7 CUB-like domain HRM PF02793.22 KFP00139.1 - 0.33 11.3 84.4 0.31 11.4 0.4 16.6 16 1 1 17 17 17 0 Hormone receptor domain DERM PF14704.6 KFP00139.1 - 1.7 9.1 4.4 1.3e+02 3.0 0.5 5.6 3 2 1 4 4 4 0 Dermatopontin CUB PF00431.20 KFP00140.1 - 2.1e-22 79.5 0.0 2.7e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 CUB domain DUF4688 PF15752.5 KFP00141.1 - 0.001 18.4 0.5 0.0011 18.2 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4688) Plasmodium_Vir PF05795.11 KFP00141.1 - 0.16 11.3 2.9 0.2 11.0 2.9 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4688 PF15752.5 KFP00142.1 - 5.7e-25 88.4 22.8 6.2e-25 88.3 22.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4688) Connexin PF00029.19 KFP00143.1 - 3e-80 269.4 9.5 4e-78 262.4 9.5 2.0 1 1 0 1 1 1 1 Connexin Connexin PF00029.19 KFP00144.1 - 3.5e-81 272.4 10.8 1e-79 267.6 10.8 2.0 1 1 0 1 1 1 1 Connexin 7tm_1 PF00001.21 KFP00144.1 - 0.0021 17.5 4.2 0.22 10.8 1.2 2.1 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) Ninjurin PF04923.12 KFP00144.1 - 0.032 14.2 0.3 1.1 9.3 0.0 2.9 4 0 0 4 4 4 0 Ninjurin UbiA PF01040.18 KFP00144.1 - 0.039 13.3 0.1 0.081 12.2 0.0 1.5 2 0 0 2 2 2 0 UbiA prenyltransferase family Connexin PF00029.19 KFP00145.1 - 1.3e-100 335.9 2.1 1.6e-100 335.7 2.1 1.1 1 0 0 1 1 1 1 Connexin Connexin43 PF03508.13 KFP00145.1 - 0.0021 17.6 5.1 0.0046 16.5 5.1 1.5 1 0 0 1 1 1 1 Gap junction alpha-1 protein (Cx43) AA_permease_2 PF13520.6 KFP00145.1 - 0.011 14.6 0.1 0.15 10.8 0.1 2.1 2 0 0 2 2 2 0 Amino acid permease UPF0767 PF15990.5 KFP00146.1 - 4e-34 116.6 0.0 4.4e-34 116.5 0.0 1.0 1 0 0 1 1 1 1 UPF0767 family DoxX_2 PF13564.6 KFP00147.1 - 0.044 13.9 0.1 0.045 13.9 0.1 1.1 1 0 0 1 1 1 0 DoxX-like family RRM_1 PF00076.22 KFP00148.1 - 1.5e-30 104.8 0.1 7.3e-15 54.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.11 KFP00148.1 - 5.6e-29 100.1 1.5 1.4e-28 98.8 1.5 1.8 1 0 0 1 1 1 1 NOPS (NUC059) domain RRM_7 PF16367.5 KFP00148.1 - 0.0015 18.6 0.0 0.014 15.5 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif AAA_21 PF13304.6 KFP00148.1 - 0.08 12.7 0.4 0.13 12.1 0.4 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF3504 PF12012.8 KFP00149.1 - 2.9e-64 215.9 1.4 2.9e-64 215.9 1.4 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3504) zf-FCS PF06467.14 KFP00149.1 - 3.7e-48 161.2 101.9 5.9e-09 35.7 5.0 11.2 10 1 1 11 11 11 10 MYM-type Zinc finger with FCS sequence motif YHS PF04945.13 KFP00149.1 - 0.014 15.4 42.2 0.15 12.2 0.9 8.5 9 0 0 9 9 9 0 YHS domain Ifi-6-16 PF06140.13 KFP00150.1 - 4.5e-26 90.6 22.8 5e-26 90.4 22.8 1.0 1 0 0 1 1 1 1 Interferon-induced 6-16 family PKD PF00801.20 KFP00151.1 - 1.3e-12 47.4 9.0 0.0067 16.2 0.1 5.6 5 0 0 5 5 5 4 PKD domain Y_Y_Y PF07495.13 KFP00151.1 - 2.9e-12 46.4 1.0 0.0079 16.1 0.0 5.2 5 0 0 5 5 5 3 Y_Y_Y domain Big_9 PF17963.1 KFP00151.1 - 1.3e-10 41.9 36.0 0.00093 19.9 1.3 5.4 5 0 0 5 5 5 4 Bacterial Ig domain DUF4625 PF15418.6 KFP00151.1 - 3.3e-10 40.3 0.1 0.5 10.6 0.0 4.4 4 0 0 4 4 4 4 Domain of unknown function (DUF4625) He_PIG PF05345.12 KFP00151.1 - 1.9e-07 31.2 2.1 0.33 11.2 0.0 5.2 5 0 0 5 5 5 2 Putative Ig domain DUF4998 PF16389.5 KFP00151.1 - 4.8e-06 26.3 1.1 0.59 9.7 0.0 4.1 5 0 0 5 5 5 2 Domain of unknown function DUF5013 PF16405.5 KFP00151.1 - 0.00057 20.2 1.1 0.41 10.9 0.0 4.0 4 1 0 4 4 4 1 Domain of unknown function (DUF5013) Wzt_C PF14524.6 KFP00151.1 - 0.00071 19.6 0.0 7.4 6.6 0.0 4.1 4 0 0 4 4 4 1 Wzt C-terminal domain AMPK1_CBM PF16561.5 KFP00151.1 - 0.0015 18.7 0.2 2 8.7 0.0 4.5 6 0 0 6 6 6 1 Glycogen recognition site of AMP-activated protein kinase Cadherin PF00028.17 KFP00151.1 - 0.0042 17.5 3.9 8 7.0 0.1 4.5 4 0 0 4 4 4 1 Cadherin domain Cadherin_5 PF17892.1 KFP00151.1 - 0.008 16.1 4.2 1.9 8.5 0.1 4.3 4 0 0 4 4 4 1 Cadherin-like domain fn3 PF00041.21 KFP00151.1 - 0.011 16.1 0.4 0.46 10.9 0.1 3.4 3 0 0 3 3 3 0 Fibronectin type III domain CopC PF04234.12 KFP00151.1 - 0.053 14.6 3.7 12 7.0 0.1 4.1 4 0 0 4 4 3 0 CopC domain DUF5011 PF16403.5 KFP00151.1 - 0.065 13.4 8.3 31 4.8 0.1 4.9 5 0 0 5 5 5 0 Domain of unknown function (DUF5011) PAN_4 PF14295.6 KFP00151.1 - 2.5 8.1 11.8 13 5.7 6.6 2.5 2 0 0 2 2 2 0 PAN domain Neurochondrin PF05536.11 KFP00152.1 - 4.5e-228 758.5 0.0 5.2e-228 758.3 0.0 1.0 1 0 0 1 1 1 1 Neurochondrin TF_AP-2 PF03299.14 KFP00153.1 - 6.8e-86 287.3 0.0 8e-86 287.1 0.0 1.0 1 0 0 1 1 1 1 Transcription factor AP-2 Proteasome PF00227.26 KFP00154.1 - 5.8e-35 120.5 0.0 6.3e-35 120.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF4653 PF15546.6 KFP00155.1 - 4.8e-77 259.1 0.1 5.5e-77 258.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4653) Piwi PF02171.17 KFP00157.1 - 3.8e-110 367.9 0.0 5.5e-110 367.3 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 KFP00157.1 - 4.4e-33 113.4 0.4 1.4e-32 111.8 0.1 2.1 2 0 0 2 2 2 1 Mid domain of argonaute ArgoN PF16486.5 KFP00157.1 - 3.3e-30 105.5 0.0 8.9e-30 104.1 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 KFP00157.1 - 4.2e-28 97.8 1.9 7.2e-28 97.1 1.9 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 KFP00157.1 - 1.3e-22 79.2 0.1 2.8e-22 78.1 0.1 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KFP00157.1 - 3.4e-15 56.1 0.0 7.7e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain Piwi PF02171.17 KFP00158.1 - 7.5e-114 380.0 0.0 1.1e-113 379.5 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 KFP00158.1 - 1e-32 112.2 0.4 3.5e-32 110.5 0.1 2.2 2 0 0 2 2 2 1 Mid domain of argonaute PAZ PF02170.22 KFP00158.1 - 8e-29 100.2 0.8 1.3e-28 99.5 0.8 1.3 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 KFP00158.1 - 4.2e-26 92.2 0.0 1.2e-25 90.7 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KFP00158.1 - 1.4e-22 79.1 0.0 3.2e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KFP00158.1 - 1.1e-10 41.7 0.1 3.3e-10 40.1 0.0 2.0 2 0 0 2 2 2 1 Argonaute linker 2 domain Tektin PF03148.14 KFP00159.1 - 6.7e-131 436.6 40.4 8.3e-131 436.3 40.4 1.0 1 0 0 1 1 1 1 Tektin family DUF1664 PF07889.12 KFP00159.1 - 0.00085 19.4 15.4 0.23 11.5 1.2 4.5 4 2 0 4 4 4 3 Protein of unknown function (DUF1664) COG5 PF10392.9 KFP00159.1 - 0.23 11.6 14.8 8.9 6.5 0.6 4.2 2 2 2 4 4 4 0 Golgi transport complex subunit 5 DUF948 PF06103.11 KFP00159.1 - 0.83 10.0 8.8 11 6.4 0.2 4.2 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF5082 PF16888.5 KFP00159.1 - 1.4 9.2 21.6 2.7 8.3 2.3 4.4 3 1 1 4 4 4 0 Domain of unknown function (DUF5082) GAS PF13851.6 KFP00159.1 - 2.4 7.4 30.6 0.3 10.4 7.7 4.4 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding COG2 PF06148.11 KFP00159.1 - 2.7 8.1 16.4 6.6 6.8 0.4 4.3 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Erp_C PF06780.11 KFP00159.1 - 3.6 7.6 7.1 2 8.4 0.0 3.3 2 2 1 4 4 4 0 Erp protein C-terminus LPP PF04728.13 KFP00159.1 - 4.9 7.6 14.9 0.51 10.8 0.1 4.6 5 1 0 5 5 5 0 Lipoprotein leucine-zipper Prominin PF05478.11 KFP00159.1 - 5.5 4.8 12.7 4.9 5.0 2.3 3.1 3 0 0 3 3 3 0 Prominin ADP_ribosyl_GH PF03747.14 KFP00160.1 - 5.2e-56 190.5 0.0 5.9e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase C1q PF00386.21 KFP00161.1 - 1.9e-15 57.2 0.3 2.2e-15 57.0 0.3 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFP00161.1 - 1.1e-09 37.9 31.0 2.8e-08 33.4 31.0 2.1 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) TRAPP PF04051.16 KFP00162.1 - 3.2e-37 127.5 0.0 3.7e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Glyco_hydro_3_C PF01915.22 KFP00163.1 - 6.6e-17 62.1 0.0 8.5e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KFP00164.1 - 2.5e-17 62.8 1.0 4.1e-17 62.0 1.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain THRAP3_BCLAF1 PF15440.6 KFP00165.1 - 4.9e-197 657.0 112.1 4.9e-197 657.0 112.1 2.3 2 0 0 2 2 2 1 THRAP3/BCLAF1 family FAM176 PF14851.6 KFP00166.1 - 4.8e-49 165.8 0.0 5.6e-49 165.5 0.0 1.1 1 0 0 1 1 1 1 FAM176 family Pkinase PF00069.25 KFP00167.1 - 2.9e-37 128.5 0.0 4.4e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP00167.1 - 2.1e-20 73.1 0.0 3.4e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP00167.1 - 3.3e-05 23.3 1.2 0.00061 19.2 0.1 2.5 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFP00167.1 - 0.00069 18.5 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFP00167.1 - 0.0064 15.5 0.7 0.015 14.2 0.7 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFP00167.1 - 0.033 13.6 0.1 0.061 12.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LSM PF01423.22 KFP00168.1 - 5.9e-13 48.3 0.2 7.9e-13 47.9 0.2 1.2 1 0 0 1 1 1 1 LSM domain DUF4903 PF16246.5 KFP00168.1 - 0.2 11.3 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4903) Oscp1 PF10188.9 KFP00169.1 - 4.6e-70 235.3 2.1 6.4e-70 234.8 2.1 1.1 1 0 0 1 1 1 1 Organic solute transport protein 1 Lep_receptor_Ig PF06328.11 KFP00170.1 - 3.6e-15 55.7 0.3 2.1e-14 53.2 0.0 2.3 2 0 0 2 2 2 1 Ig-like C2-type domain fn3 PF00041.21 KFP00170.1 - 2.4e-09 37.4 0.2 5.8e-08 33.0 0.1 2.9 3 0 0 3 3 3 1 Fibronectin type III domain fn3_2 PF16893.5 KFP00170.1 - 8.1e-06 25.9 0.4 0.00045 20.3 0.2 2.7 2 1 0 2 2 2 1 Fibronectin type III domain Hum_adeno_E3A PF05393.11 KFP00170.1 - 0.052 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein C2-set_2 PF08205.12 KFP00170.1 - 0.087 12.9 0.4 9.7 6.3 0.1 2.5 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain ANF_receptor PF01094.28 KFP00171.1 - 1.1e-71 241.8 0.0 1.4e-71 241.4 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 KFP00171.1 - 6.3e-54 181.9 0.1 1e-53 181.2 0.1 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFP00171.1 - 3.5e-46 156.1 0.0 1.5e-45 154.0 0.0 2.1 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFP00171.1 - 1.7e-18 66.9 0.0 3.9e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.6 KFP00171.1 - 0.00018 21.3 0.0 0.00034 20.4 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein DUF2569 PF10754.9 KFP00171.1 - 0.24 11.8 1.8 0.36 11.3 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2569) RNase_Zc3h12a PF11977.8 KFP00172.1 - 9.6e-55 184.6 0.0 1.3e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Regnase_1_C PF18561.1 KFP00172.1 - 3.5e-25 87.5 0.1 6.4e-25 86.6 0.1 1.5 1 0 0 1 1 1 1 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain zf-CCCH_4 PF18044.1 KFP00172.1 - 3.4e-05 23.5 3.5 8.2e-05 22.3 3.5 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 KFP00172.1 - 0.024 14.6 5.2 0.056 13.4 2.8 2.4 1 1 1 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KFP00172.1 - 0.039 14.4 6.0 0.086 13.3 6.0 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger NuA4 PF09340.10 KFP00173.1 - 0.061 13.2 2.4 0.12 12.3 0.2 2.2 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 SMYLE_N PF18615.1 KFP00173.1 - 0.31 10.6 2.5 0.38 10.3 2.5 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain FHA PF00498.26 KFP00174.1 - 2.6e-14 53.3 0.1 4.6e-14 52.5 0.1 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFP00174.1 - 0.0041 17.4 0.0 0.17 12.2 0.0 2.4 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Ax_dynein_light PF10211.9 KFP00175.1 - 1.5e-64 217.4 16.5 1.6e-64 217.3 16.5 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain Jnk-SapK_ap_N PF09744.9 KFP00175.1 - 0.0016 18.7 9.9 0.002 18.4 9.9 1.3 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Mei5 PF10376.9 KFP00175.1 - 0.007 16.2 6.3 0.0077 16.1 6.3 1.2 1 0 0 1 1 1 1 Double-strand recombination repair protein DUF4164 PF13747.6 KFP00175.1 - 0.044 14.1 9.9 0.035 14.4 7.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF724 PF05266.14 KFP00175.1 - 0.1 12.4 8.6 0.13 12.1 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Spc24 PF08286.11 KFP00175.1 - 0.23 11.7 9.5 0.35 11.1 9.5 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 GrpE PF01025.19 KFP00175.1 - 0.44 10.2 13.5 0.65 9.6 13.2 1.4 1 1 0 1 1 1 0 GrpE ABC_tran_CTD PF16326.5 KFP00175.1 - 0.57 10.5 14.6 2.8 8.3 14.5 2.1 1 1 0 1 1 1 0 ABC transporter C-terminal domain DUF2681 PF10883.8 KFP00175.1 - 0.97 9.9 8.7 2.3 8.7 8.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) PRKG1_interact PF15898.5 KFP00175.1 - 1.3 10.0 15.5 3.1 8.8 15.5 1.7 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF4337 PF14235.6 KFP00175.1 - 5.2 7.2 6.6 6.9 6.8 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) WD40_alt PF14077.6 KFP00175.1 - 6.6 6.7 9.2 10 6.1 1.5 2.5 2 0 0 2 2 2 0 Alternative WD40 repeat motif M PF02370.16 KFP00175.1 - 6.9 7.6 10.8 0.48 11.1 4.0 2.7 2 1 0 2 2 2 0 M protein repeat NGP1NT PF08153.12 KFP00176.1 - 3.5e-49 166.3 1.1 9.3e-49 164.9 1.1 1.8 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KFP00176.1 - 3.1e-17 62.7 0.3 9.2e-13 48.3 0.0 3.7 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP00176.1 - 0.00011 22.2 0.0 0.0004 20.3 0.0 2.0 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KFP00176.1 - 0.00024 20.7 0.0 0.0012 18.4 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 KFP00176.1 - 0.0084 15.6 0.2 0.28 10.6 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Dynamin_N PF00350.23 KFP00176.1 - 9.7 6.2 9.9 5.1 7.1 1.2 4.5 3 1 0 3 3 3 0 Dynamin family Furin-like_2 PF15913.5 KFP00177.1 - 3.6e-49 165.4 22.2 3.6e-49 165.4 22.2 2.0 2 0 0 2 2 2 1 Furin-like repeat, cysteine-rich TSP_1 PF00090.19 KFP00177.1 - 0.00031 20.9 4.7 0.00031 20.9 4.7 3.9 3 1 1 4 4 4 1 Thrombospondin type 1 domain CK2S PF15011.6 KFP00178.1 - 3.4e-13 49.8 0.0 4.3e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Casein Kinase 2 substrate DMA PF03474.14 KFP00178.1 - 0.021 14.4 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 DMRTA motif Borealin PF10512.9 KFP00179.1 - 9.2e-28 96.7 0.0 1.1e-27 96.5 0.0 1.0 1 0 0 1 1 1 1 Cell division cycle-associated protein 8 ASXH PF13919.6 KFP00180.1 - 6.1e-35 120.2 0.1 6.1e-35 120.2 0.1 2.9 3 0 0 3 3 3 1 Asx homology domain PHD_3 PF13922.6 KFP00180.1 - 2.2e-22 79.2 6.8 2.2e-22 79.2 6.8 4.0 5 0 0 5 5 5 1 PHD domain of transcriptional enhancer, Asx HARE-HTH PF05066.13 KFP00180.1 - 2.9e-16 59.6 0.0 7.4e-16 58.3 0.0 1.8 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain RSF PF14876.6 KFP00180.1 - 0.033 13.2 2.5 0.073 12.0 2.5 1.5 1 0 0 1 1 1 0 Respiratory growth transcriptional regulator PHD PF00628.29 KFP00180.1 - 4.4 7.3 8.9 11 6.0 8.9 1.6 1 0 0 1 1 1 0 PHD-finger DNA_methylase PF00145.17 KFP00182.1 - 5.8e-11 42.3 0.0 9.8e-10 38.3 0.0 2.0 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase PWWP PF00855.17 KFP00182.1 - 7.3e-11 42.3 1.3 1.4e-10 41.4 0.4 1.8 2 0 0 2 2 2 1 PWWP domain Innate_immun PF12782.7 KFP00182.1 - 0.0052 16.3 2.1 0.008 15.7 2.1 1.2 1 0 0 1 1 1 1 Invertebrate innate immunity transcript family TMEM214 PF10151.9 KFP00183.1 - 2e-46 158.7 0.0 2.2e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 TMEM214, C-terminal, caspase 4 activator SSF PF00474.17 KFP00185.1 - 6.6e-27 94.4 16.5 8.5e-27 94.0 16.5 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family NdhL PF10716.9 KFP00185.1 - 0.3 11.1 6.5 2.3 8.2 6.1 2.5 1 1 0 1 1 1 0 NADH dehydrogenase transmembrane subunit DUF4022 PF13214.6 KFP00185.1 - 1.3 9.3 8.0 0.61 10.4 0.4 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF4022) LRR_8 PF13855.6 KFP00186.1 - 0.0027 17.4 0.1 0.006 16.3 0.1 1.5 1 1 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.33 KFP00186.1 - 0.0058 17.0 1.0 7.9 7.5 0.0 3.0 2 0 0 2 2 2 2 Leucine Rich Repeat LRR_4 PF12799.7 KFP00186.1 - 0.11 13.0 0.2 16 6.1 0.1 2.4 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) EGF_3 PF12947.7 KFP00186.1 - 0.17 12.1 4.1 0.33 11.2 4.1 1.5 1 0 0 1 1 1 0 EGF domain Cation_efflux PF01545.21 KFP00187.1 - 3.6e-32 111.7 1.1 4.8e-32 111.3 1.1 1.2 1 0 0 1 1 1 1 Cation efflux family PRK PF00485.18 KFP00188.1 - 1.1e-56 191.7 0.0 1.2e-56 191.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KFP00188.1 - 7.8e-06 26.5 0.0 1.1e-05 26.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 KFP00188.1 - 2.4e-05 24.2 0.0 4e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 KFP00188.1 - 6.5e-05 23.1 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KFP00188.1 - 0.0045 17.4 0.5 0.09 13.2 0.5 2.2 1 1 0 1 1 1 1 AAA domain CoaE PF01121.20 KFP00188.1 - 0.0049 16.6 0.1 0.42 10.3 0.0 2.2 2 0 0 2 2 2 1 Dephospho-CoA kinase Cytidylate_kin PF02224.18 KFP00188.1 - 0.056 13.2 0.1 4.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase CbiA PF01656.23 KFP00188.1 - 0.078 13.0 0.4 1.1 9.4 0.4 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 KFP00188.1 - 0.14 11.4 0.0 0.62 9.3 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin DnaJ PF00226.31 KFP00189.1 - 4.8e-28 97.1 0.8 6.7e-28 96.6 0.8 1.2 1 0 0 1 1 1 1 DnaJ domain Corona_S2 PF01601.16 KFP00189.1 - 3.3 6.1 10.8 3.6 5.9 10.8 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Mpv17_PMP22 PF04117.12 KFP00190.1 - 1.1e-24 86.4 1.4 1.5e-24 85.9 1.4 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family CPSase_L_D2 PF02786.17 KFP00191.1 - 3.5e-67 226.0 0.3 1.7e-29 102.8 0.0 3.5 2 1 1 3 3 3 3 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.28 KFP00191.1 - 5.3e-43 147.0 0.0 1.5e-42 145.6 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 KFP00191.1 - 5.6e-34 117.1 0.0 2.1e-33 115.3 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace_N PF02729.21 KFP00191.1 - 4.6e-28 98.1 0.0 9.5e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 KFP00191.1 - 6.5e-20 71.8 0.0 1.6e-19 70.5 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Amidohydro_1 PF01979.20 KFP00191.1 - 1.3e-11 44.5 0.0 6.4e-09 35.6 0.1 2.7 2 0 0 2 2 2 2 Amidohydrolase family ATPgrasp_Ter PF15632.6 KFP00191.1 - 1.6e-11 44.1 0.1 0.00041 20.1 0.0 3.1 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 KFP00191.1 - 1.4e-08 34.5 0.6 1.2e-05 25.0 0.0 3.5 3 1 1 4 4 4 2 D-ala D-ala ligase C-terminus Peptidase_C26 PF07722.13 KFP00191.1 - 3.1e-06 27.1 1.4 0.00023 21.0 0.4 2.8 2 1 0 2 2 2 1 Peptidase C26 MGS PF02142.22 KFP00191.1 - 9.8e-06 25.7 0.0 7.8e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.22 KFP00191.1 - 0.0022 17.6 0.0 0.24 11.0 0.0 2.7 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KFP00191.1 - 0.0025 17.9 0.1 0.18 11.8 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain CPSase_sm_chain PF00988.22 KFP00192.1 - 4.3e-29 100.9 0.0 4.7e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain SNX17_FERM_C PF18116.1 KFP00193.1 - 1.1e-41 141.2 0.2 2.1e-40 137.1 0.0 2.4 2 0 0 2 2 2 1 Sorting Nexin 17 FERM C-terminal domain PX PF00787.24 KFP00193.1 - 8.4e-15 54.7 0.2 2.9e-14 53.0 0.0 1.9 2 0 0 2 2 2 1 PX domain FERM_M PF00373.18 KFP00193.1 - 0.011 16.2 0.7 0.081 13.3 0.3 2.5 2 1 1 3 3 3 0 FERM central domain RA PF00788.23 KFP00193.1 - 0.016 15.8 0.1 0.044 14.4 0.1 1.8 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Ras_bdg_2 PF14847.6 KFP00193.1 - 0.027 14.8 0.1 0.1 12.9 0.0 2.0 2 0 0 2 2 2 0 Ras-binding domain of Byr2 Nif11 PF07862.11 KFP00193.1 - 0.044 14.1 0.4 3.8 7.9 0.0 2.9 3 0 0 3 3 3 0 Nif11 domain FERM_N PF09379.10 KFP00193.1 - 0.088 12.8 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 FERM N-terminal domain Med15_fungi PF05397.12 KFP00193.1 - 0.82 10.0 4.0 0.87 9.9 0.0 2.6 3 0 0 3 3 3 0 Mediator complex subunit 15 PP2C PF00481.21 KFP00195.1 - 7.7e-62 209.2 1.1 3.7e-57 193.9 0.4 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KFP00195.1 - 0.0079 15.9 0.0 0.028 14.1 0.0 1.8 2 1 0 2 2 2 1 Protein phosphatase 2C Glutaminase PF04960.15 KFP00195.1 - 0.17 11.0 0.1 0.25 10.5 0.1 1.2 1 0 0 1 1 1 0 Glutaminase Pkinase_Tyr PF07714.17 KFP00196.1 - 6.7e-25 87.8 0.7 1.4e-24 86.8 0.7 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP00196.1 - 1e-24 87.4 2.3 2.6e-24 86.0 2.3 1.7 1 1 0 1 1 1 1 Protein kinase domain PRESAN PF09687.10 KFP00196.1 - 0.1 13.1 7.3 0.35 11.4 6.9 2.1 2 0 0 2 2 2 0 Plasmodium RESA N-terminal BCLP PF12304.8 KFP00197.1 - 8e-37 126.6 1.5 8.7e-37 126.4 1.5 1.0 1 0 0 1 1 1 1 Beta-casein like protein DUF1158 PF06643.11 KFP00197.1 - 0.82 10.2 4.8 0.37 11.3 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1158) Clathrin PF00637.20 KFP00198.1 - 3.4e-12 46.4 30.3 0.0051 16.7 0.3 10.4 6 3 4 12 12 12 4 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 KFP00198.1 - 3.2e-09 37.0 0.1 0.0047 17.2 0.0 5.2 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFP00198.1 - 1.6e-06 28.7 3.8 1.8 9.6 0.0 6.3 6 0 0 6 6 6 1 WD domain, G-beta repeat TPR_2 PF07719.17 KFP00198.1 - 0.0017 18.3 47.7 2.4 8.5 0.5 12.3 12 0 0 12 12 12 4 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 KFP00198.1 - 0.0032 16.6 0.2 0.0032 16.6 0.2 5.3 2 2 4 6 6 6 2 Coatomer WD associated region TPR_12 PF13424.6 KFP00198.1 - 0.097 13.0 35.0 8.5 6.8 0.7 10.9 11 1 0 11 11 11 0 Tetratricopeptide repeat fn1 PF00039.18 KFP00198.1 - 0.52 10.5 5.3 14 5.9 0.0 4.7 5 0 0 5 5 5 0 Fibronectin type I domain DUF4809 PF16067.5 KFP00198.1 - 0.53 10.5 2.3 2 8.6 1.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4809) TPR_7 PF13176.6 KFP00198.1 - 0.94 9.7 29.5 19 5.6 0.1 9.9 10 2 1 11 11 11 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KFP00198.1 - 2.7 8.0 19.5 2.7 8.0 0.2 6.0 5 1 1 6 6 6 0 Mad3/BUB1 homology region 1 PID PF00640.23 KFP00199.1 - 1.3e-19 70.6 0.2 1.7e-19 70.2 0.2 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID_2 PF14719.6 KFP00199.1 - 9.8e-14 51.6 0.1 1.2e-13 51.3 0.1 1.0 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFP00199.1 - 5.5e-11 42.7 0.1 7.3e-11 42.3 0.1 1.1 1 0 0 1 1 1 1 Phosphotyrosine-binding domain fn3 PF00041.21 KFP00200.1 - 3.1e-10 40.2 1.0 4.7e-10 39.7 0.1 1.8 2 0 0 2 2 2 1 Fibronectin type III domain DUF4808 PF16066.5 KFP00200.1 - 0.00018 22.0 0.0 0.00035 21.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4808) Pur_ac_phosph_N PF16656.5 KFP00200.1 - 0.0038 17.8 0.2 0.012 16.2 0.2 1.9 1 1 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain DUF4992 PF16383.5 KFP00200.1 - 0.017 14.7 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function zf-C2H2_4 PF13894.6 KFP00201.1 - 3.7e-10 39.8 37.4 0.017 15.9 3.5 6.5 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP00201.1 - 1.3e-07 31.7 31.2 0.0014 19.0 3.5 6.3 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-BED PF02892.15 KFP00201.1 - 6.8e-07 29.2 27.5 0.041 13.9 5.0 5.5 4 1 1 5 5 5 4 BED zinc finger zf-C2H2_jaz PF12171.8 KFP00201.1 - 2.5e-06 27.6 14.5 0.0014 18.9 1.3 3.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding IBR PF01485.21 KFP00201.1 - 1.7e-05 25.0 17.3 0.1 12.8 2.0 3.6 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain CpXC PF14353.6 KFP00201.1 - 1.8e-05 24.8 10.0 0.0052 16.8 0.1 3.7 3 1 0 3 3 3 2 CpXC protein zf-FCS PF06467.14 KFP00201.1 - 0.00036 20.4 3.4 0.078 12.9 0.2 3.3 3 0 0 3 3 2 2 MYM-type Zinc finger with FCS sequence motif zf-Di19 PF05605.12 KFP00201.1 - 0.00064 20.0 14.2 1.2 9.5 0.4 4.4 4 0 0 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KFP00201.1 - 0.0029 17.9 21.8 0.27 11.6 0.2 4.6 3 2 1 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 KFP00201.1 - 0.0088 16.7 12.6 0.35 11.5 0.0 4.1 3 1 2 5 5 5 2 Zinc finger C2H2-type, 3 repeats GAGA PF09237.11 KFP00201.1 - 0.025 14.4 1.6 0.12 12.3 0.0 2.7 2 0 0 2 2 2 0 GAGA factor Agenet PF05641.12 KFP00201.1 - 0.026 15.0 0.0 0.82 10.2 0.0 2.7 2 0 0 2 2 2 0 Agenet domain PriA_CRR PF18319.1 KFP00201.1 - 0.038 14.0 12.3 0.36 10.9 1.0 3.5 3 0 0 3 3 3 0 PriA DNA helicase Cys-rich region (CRR) domain zf_PR_Knuckle PF18445.1 KFP00201.1 - 0.11 12.4 0.3 2.7 7.9 0.0 2.9 2 1 0 2 2 2 0 PR zinc knuckle motif zf-C2H2_aberr PF17017.5 KFP00201.1 - 0.28 11.3 27.5 0.1 12.7 0.5 5.0 4 3 1 5 5 5 0 Aberrant zinc-finger zf-C2HE PF16278.5 KFP00201.1 - 1 9.9 28.3 1.5 9.3 2.1 6.1 5 2 1 6 6 5 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_12 PF18658.1 KFP00201.1 - 2.6 7.7 13.2 13 5.4 2.6 4.2 3 1 1 4 4 4 0 Zinc-finger C2H2-type zinc_ribbon_2 PF13240.6 KFP00201.1 - 2.6 7.9 13.5 6.9 6.5 0.7 3.9 4 0 0 4 4 4 0 zinc-ribbon domain zf-met PF12874.7 KFP00201.1 - 8 7.0 20.5 0.47 10.9 0.3 4.5 5 0 0 5 5 5 0 Zinc-finger of C2H2 type ATP_bind_1 PF03029.17 KFP00202.1 - 3.8e-70 236.4 0.2 5.3e-70 235.9 0.2 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KFP00202.1 - 4.4e-07 29.6 0.2 9.8e-07 28.5 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KFP00202.1 - 1.5e-05 24.6 0.1 3.1e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 KFP00202.1 - 0.0019 18.2 0.0 0.0041 17.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFP00202.1 - 0.0063 15.9 1.0 0.0073 15.7 0.1 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region cobW PF02492.19 KFP00202.1 - 0.052 13.1 0.1 0.12 12.0 0.1 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NOG1 PF06858.14 KFP00202.1 - 0.13 12.0 0.4 0.56 10.0 0.4 2.0 1 1 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) LSM PF01423.22 KFP00203.1 - 1.4e-16 59.9 0.4 2e-16 59.4 0.4 1.2 1 0 0 1 1 1 1 LSM domain Ank PF00023.30 KFP00204.1 - 7e-31 105.3 2.7 2e-07 31.1 0.3 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 KFP00204.1 - 1.2e-30 106.0 0.3 2.5e-15 56.8 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP00204.1 - 6.2e-29 100.0 1.0 2.6e-09 37.4 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP00204.1 - 9.9e-29 96.2 0.8 2.2e-06 27.5 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KFP00204.1 - 3.4e-27 94.2 2.2 1.5e-09 37.9 0.0 3.1 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Yae1_N PF09811.9 KFP00205.1 - 3.1e-12 46.0 38.4 6.8e+03 -3.1 38.4 4.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Ion_trans PF00520.31 KFP00206.1 - 1.3e-28 99.8 11.9 1.8e-28 99.4 11.9 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFP00206.1 - 8e-28 96.6 0.1 2.2e-27 95.2 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Shal-type PF11601.8 KFP00206.1 - 2.3e-13 49.4 14.9 4.4e-13 48.5 14.9 1.5 1 0 0 1 1 1 1 Shal-type voltage-gated potassium channels, N-terminal BTB_3 PF16017.5 KFP00206.1 - 0.0011 19.0 0.0 0.0034 17.4 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFP00206.1 - 0.016 15.1 4.0 0.016 15.1 4.0 2.8 3 0 0 3 3 3 0 Ion channel PKD_channel PF08016.12 KFP00206.1 - 0.058 12.1 9.8 0.038 12.7 7.8 1.5 1 1 0 1 1 1 0 Polycystin cation channel RVT_1 PF00078.27 KFP00207.1 - 0.00028 20.5 0.0 0.0004 20.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MuF_C PF18819.1 KFP00207.1 - 0.16 12.0 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Phage MuF-C-terminal domain DUF3399 PF11879.8 KFP00208.1 - 8.1e-43 145.0 8.7 8.1e-43 145.0 8.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3399) Ion_trans PF00520.31 KFP00208.1 - 2.1e-06 27.1 0.0 2.8e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFP00208.1 - 0.001 19.0 0.1 0.0015 18.5 0.1 1.3 1 0 0 1 1 1 1 Ion channel Tetraspanin PF00335.20 KFP00209.1 - 1.8e-32 112.9 7.4 2.1e-32 112.7 7.4 1.1 1 0 0 1 1 1 1 Tetraspanin family SUR7 PF06687.12 KFP00209.1 - 0.15 11.7 4.4 0.11 12.1 2.4 1.7 2 0 0 2 2 2 0 SUR7/PalI family MscS_TM PF12794.7 KFP00209.1 - 3.9 6.2 9.3 0.43 9.4 4.9 1.6 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 ING PF12998.7 KFP00210.1 - 6.3e-16 58.8 2.8 1.8e-15 57.3 2.8 1.8 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KFP00210.1 - 1.4e-06 28.0 7.3 2.8e-06 27.1 7.3 1.5 1 0 0 1 1 1 1 PHD-finger Pet100 PF09803.9 KFP00210.1 - 0.073 13.6 1.3 0.2 12.2 1.3 1.7 1 0 0 1 1 1 0 Pet100 zf-HC5HC2H PF13771.6 KFP00210.1 - 0.16 12.3 2.2 0.39 11.0 2.1 1.9 1 1 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 KFP00210.1 - 0.29 10.7 3.0 0.57 9.8 3.0 1.5 1 0 0 1 1 1 0 PHD-finger ILEI PF15711.5 KFP00212.1 - 1.9e-28 98.8 0.0 2.9e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Interleukin-like EMT inducer Y_phosphatase PF00102.27 KFP00213.1 - 1.7e-146 486.0 5.8 2.4e-86 289.2 1.1 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Carb_anhydrase PF00194.21 KFP00213.1 - 5.1e-73 245.7 0.2 8.8e-73 245.0 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase fn3 PF00041.21 KFP00213.1 - 6.5e-13 48.8 0.1 2.5e-12 46.9 0.1 2.2 1 0 0 1 1 1 1 Fibronectin type III domain DSPc PF00782.20 KFP00213.1 - 0.00038 20.3 0.3 0.02 14.7 0.0 3.3 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP00213.1 - 0.0047 16.9 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFP00213.1 - 0.056 13.6 0.1 0.3 11.2 0.0 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate Orf78 PF06024.12 KFP00213.1 - 3.7 7.9 4.9 0.76 10.1 0.0 2.3 2 0 0 2 2 2 0 Orf78 (ac78) Sacchrp_dh_C PF16653.5 KFP00214.1 - 1.6e-81 274.3 0.1 3.5e-81 273.2 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 KFP00214.1 - 1.7e-27 96.4 0.6 1.6e-26 93.2 0.0 2.6 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 KFP00214.1 - 3.5e-22 79.0 0.2 6.3e-22 78.2 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 KFP00214.1 - 3.4e-08 33.1 0.1 5.7e-05 22.5 0.0 3.1 2 1 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KFP00214.1 - 0.0057 16.7 0.1 0.013 15.5 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 KFP00214.1 - 0.0062 17.0 0.2 0.019 15.4 0.1 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain ThiF PF00899.21 KFP00214.1 - 0.2 11.0 0.7 0.7 9.2 0.1 1.9 1 1 1 2 2 2 0 ThiF family DUF1041 PF06292.17 KFP00215.1 - 1.1e-30 106.2 1.5 3.6e-30 104.5 1.5 2.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1041) PH PF00169.29 KFP00215.1 - 1.2e-08 35.4 0.0 2.9e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 PH domain ATP-synt_S1 PF05827.12 KFP00216.1 - 1.4e-53 180.6 0.4 2.9e-53 179.6 0.1 1.7 2 0 0 2 2 2 1 Vacuolar ATP synthase subunit S1 (ATP6S1) IQ PF00612.27 KFP00217.1 - 0.024 14.4 0.1 0.073 12.9 0.1 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif ETC_C1_NDUFA5 PF04716.14 KFP00218.1 - 5.1e-27 93.5 0.1 8.1e-27 92.8 0.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Complex1_LYR PF05347.15 KFP00218.1 - 0.0048 16.9 0.1 0.0069 16.4 0.1 1.3 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Tropomodulin PF03250.14 KFP00219.1 - 1.5e-16 60.7 15.7 1.5e-16 60.7 15.7 2.9 2 1 0 2 2 2 1 Tropomodulin LRR_6 PF13516.6 KFP00219.1 - 0.0029 17.5 0.0 0.0091 16.0 0.0 1.9 1 0 0 1 1 1 1 Leucine Rich repeat WH2 PF02205.20 KFP00219.1 - 0.058 13.3 0.0 0.2 11.5 0.0 2.0 1 0 0 1 1 1 0 WH2 motif WH1 PF00568.23 KFP00220.1 - 2.8e-36 123.8 0.1 4.1e-36 123.3 0.1 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 KFP00220.1 - 1.5e-18 66.9 0.3 3.9e-18 65.6 0.1 1.9 2 0 0 2 2 2 1 P21-Rho-binding domain WH2 PF02205.20 KFP00220.1 - 1.2e-16 59.9 1.7 1.6e-07 30.9 0.1 2.7 2 0 0 2 2 2 2 WH2 motif PQQ PF01011.21 KFP00220.1 - 0.071 13.1 0.0 0.25 11.4 0.0 2.0 1 0 0 1 1 1 0 PQQ enzyme repeat DUF4918 PF16265.5 KFP00220.1 - 0.086 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4918) Glyco_hydro_56 PF01630.18 KFP00221.1 - 7.2e-147 488.8 0.3 8.4e-147 488.5 0.3 1.0 1 0 0 1 1 1 1 Hyaluronidase EGF PF00008.27 KFP00221.1 - 0.0072 16.6 2.6 0.19 12.1 0.0 2.5 2 0 0 2 2 2 1 EGF-like domain EGF_2 PF07974.13 KFP00221.1 - 0.077 13.4 5.9 0.31 11.4 0.3 2.5 2 0 0 2 2 2 0 EGF-like domain Glyco_hydro_56 PF01630.18 KFP00222.1 - 5.3e-144 479.3 0.2 6.2e-144 479.1 0.2 1.0 1 0 0 1 1 1 1 Hyaluronidase Arf PF00025.21 KFP00223.1 - 1.3e-38 132.2 0.0 1.5e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFP00223.1 - 8.7e-13 48.2 0.0 9.8e-13 48.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP00223.1 - 3.4e-10 40.2 0.0 5.3e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KFP00223.1 - 9.5e-06 25.0 0.0 1.2e-05 24.7 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.12 KFP00223.1 - 4e-05 23.1 0.0 4.6e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP00223.1 - 0.017 15.2 0.0 0.22 11.6 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase 7tm_1 PF00001.21 KFP00224.1 - 5.7e-32 111.1 17.8 7.3e-32 110.7 17.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) COX1 PF00115.20 KFP00224.1 - 0.00026 20.0 2.1 0.00026 20.0 2.1 1.7 2 0 0 2 2 2 1 Cytochrome C and Quinol oxidase polypeptide I DUF4500 PF14937.6 KFP00224.1 - 0.43 10.6 2.8 1.3 9.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) POT1PC PF16686.5 KFP00225.1 - 1.1e-39 135.8 0.0 3e-38 131.1 0.0 2.6 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KFP00225.1 - 1.2e-35 122.5 0.1 3.8e-35 120.8 0.0 2.0 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.25 KFP00225.1 - 9.5e-05 22.3 1.0 6.2 6.9 0.0 5.0 4 1 1 5 5 5 2 OB-fold nucleic acid binding domain REPA_OB_2 PF16900.5 KFP00225.1 - 0.0015 18.4 0.0 0.006 16.5 0.0 2.0 2 0 0 2 2 2 1 Replication protein A OB domain ANF_receptor PF01094.28 KFP00226.1 - 1.5e-104 349.9 0.0 1.9e-104 349.6 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 KFP00226.1 - 3.2e-61 207.1 16.1 5.7e-61 206.3 16.1 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 KFP00226.1 - 1.4e-12 47.4 11.5 2.8e-12 46.4 11.5 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.6 KFP00226.1 - 4.8e-08 33.0 0.0 4.1e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Periplasmic binding protein zf-C2H2_assoc2 PF16624.5 KFP00227.1 - 7.1e-29 100.7 31.2 6.6e-23 81.5 16.3 4.7 4 2 2 6 6 5 2 Unstructured region upstream of a zinc-finger zf-C2H2 PF00096.26 KFP00227.1 - 2.1e-16 59.3 57.5 0.0023 18.3 1.6 7.7 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP00227.1 - 2.3e-15 56.0 56.1 0.0094 16.7 1.3 7.6 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFP00227.1 - 4e-14 52.0 11.8 5.1e-14 51.7 5.3 6.6 7 0 0 7 7 7 3 zinc-finger C2H2-type zf-met PF12874.7 KFP00227.1 - 4.9e-07 29.9 23.0 0.0026 18.1 0.6 6.5 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFP00227.1 - 1.2e-05 25.5 28.0 0.00082 19.6 1.4 5.6 5 0 0 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 KFP00227.1 - 1.7e-05 24.5 33.8 4.6e-05 23.1 0.6 6.3 6 0 0 6 6 6 2 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KFP00227.1 - 6e-05 23.3 38.4 0.19 12.1 4.9 7.1 5 2 2 7 7 7 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KFP00227.1 - 0.0004 20.6 1.4 0.0004 20.6 1.4 7.6 8 0 0 8 8 8 3 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 KFP00227.1 - 0.0022 17.8 9.8 7.5 6.5 0.0 4.8 5 0 0 5 5 5 2 C2H2 type zinc-finger (1 copy) zf-C2H2_8 PF15909.5 KFP00227.1 - 0.006 16.9 3.6 0.006 16.9 3.6 4.3 5 1 0 5 5 5 1 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 KFP00227.1 - 0.016 15.6 0.4 0.016 15.6 0.4 10.1 11 1 0 11 11 9 0 Zinc-finger double domain Not1 PF04054.15 KFP00227.1 - 0.037 13.0 0.3 0.1 11.5 0.3 1.7 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 zf-C2H2_6 PF13912.6 KFP00227.1 - 0.06 13.4 0.6 0.06 13.4 0.6 7.1 7 0 0 7 7 7 0 C2H2-type zinc finger CpXC PF14353.6 KFP00227.1 - 0.23 11.5 0.0 0.23 11.5 0.0 3.8 4 2 0 4 4 4 0 CpXC protein zf-C2H2_12 PF18658.1 KFP00227.1 - 0.41 10.2 15.7 0.16 11.5 0.8 5.0 5 0 0 5 5 5 0 Zinc-finger C2H2-type DUF4535 PF15054.6 KFP00227.1 - 2.4 8.0 4.5 7 6.5 4.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) DUF2256 PF10013.9 KFP00227.1 - 5.7 7.2 20.1 11 6.2 0.0 5.4 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) Plexin_cytopl PF08337.12 KFP00228.1 - 1.9e-221 736.6 11.6 4.7e-221 735.3 11.6 1.7 1 1 0 1 1 1 1 Plexin cytoplasmic RasGAP domain Sema PF01403.19 KFP00228.1 - 2.6e-64 217.6 5.2 2.6e-64 217.6 5.2 2.3 1 1 1 2 2 2 1 Sema domain TIG PF01833.24 KFP00228.1 - 2.9e-33 113.8 15.6 5.5e-11 42.4 0.1 5.7 6 0 0 6 6 6 4 IPT/TIG domain TIG_plexin PF17960.1 KFP00228.1 - 8.2e-15 54.6 0.2 8.2e-15 54.6 0.2 3.3 3 0 0 3 3 3 1 TIG domain PSI PF01437.25 KFP00228.1 - 3.3e-14 53.2 51.6 2.6e-09 37.5 16.2 3.7 3 0 0 3 3 3 3 Plexin repeat RasGAP PF00616.19 KFP00228.1 - 0.00011 21.9 0.0 0.0029 17.4 0.0 2.9 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase ubiquitin PF00240.23 KFP00228.1 - 0.043 13.6 0.3 0.9 9.3 0.0 3.0 3 0 0 3 3 3 0 Ubiquitin family ECSCR PF15820.5 KFP00228.1 - 0.072 12.9 0.1 0.21 11.4 0.1 1.8 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator ARL2_Bind_BART PF11527.8 KFP00228.1 - 0.61 10.2 3.9 0.59 10.3 0.2 2.9 3 0 0 3 3 3 0 The ARF-like 2 binding protein BART Pkinase PF00069.25 KFP00229.1 - 5.2e-61 206.3 0.1 6.1e-61 206.1 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP00229.1 - 1e-26 93.8 0.1 1.3e-26 93.5 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFP00229.1 - 5.4e-06 25.9 0.3 7.7e-06 25.4 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP00229.1 - 0.00097 19.1 0.0 0.015 15.3 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFP00229.1 - 0.017 14.4 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 KFP00230.1 - 1.4e-63 214.8 0.3 1.7e-63 214.5 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP00230.1 - 1.5e-27 96.6 0.1 1.9e-27 96.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFP00230.1 - 9.8e-05 21.4 0.1 9.8e-05 21.4 0.1 1.5 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KFP00230.1 - 0.00038 20.4 0.0 0.0011 19.0 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFP00230.1 - 0.0037 16.6 0.1 0.0073 15.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFP00230.1 - 0.0041 16.5 0.0 0.0062 15.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like DUF3381 PF11861.8 KFP00230.1 - 0.03 14.1 1.1 0.16 11.7 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) FTA2 PF13095.6 KFP00230.1 - 0.088 12.4 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 UvrD_C PF13361.6 KFP00230.1 - 0.091 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain SSXRD PF09514.10 KFP00230.1 - 0.49 10.0 2.3 5 6.8 0.0 2.5 2 0 0 2 2 2 0 SSXRD motif Fz PF01392.22 KFP00231.1 - 2.2e-27 95.9 5.1 2.2e-27 95.9 5.1 1.9 2 1 0 2 2 2 1 Fz domain DUF1182 PF06681.13 KFP00231.1 - 0.046 13.3 0.2 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1182) RE_SinI PF09570.10 KFP00231.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 SinI restriction endonuclease Hist_deacetyl PF00850.19 KFP00232.1 - 4.7e-82 275.9 0.0 5.8e-82 275.6 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain GCP_C_terminal PF04130.13 KFP00233.1 - 9.6e-61 205.9 9.5 9.6e-61 205.9 9.5 2.2 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KFP00233.1 - 7.1e-38 131.0 0.2 1.4e-37 129.9 0.2 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF4573 PF15140.6 KFP00233.1 - 1.6e-05 24.8 0.0 3.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) UPF0061 PF02696.14 KFP00234.1 - 5.7e-111 371.6 0.0 8.2e-111 371.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Metallopep PF12044.8 KFP00234.1 - 0.025 13.2 0.2 0.036 12.7 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase family COMM_domain PF07258.14 KFP00234.1 - 0.047 13.8 0.6 0.26 11.4 0.6 2.2 1 1 0 1 1 1 0 COMM domain XPC-binding PF09280.11 KFP00234.1 - 0.072 12.8 2.7 0.19 11.5 1.0 2.6 3 0 0 3 3 3 0 XPC-binding domain SRP19 PF01922.17 KFP00234.1 - 0.081 13.9 0.2 1 10.3 0.1 2.4 2 0 0 2 2 2 0 SRP19 protein TraB PF01963.17 KFP00235.1 - 1.2e-28 100.8 0.1 2.5e-28 99.7 0.0 1.5 1 1 1 2 2 2 1 TraB family Tetraspanin PF00335.20 KFP00236.1 - 0.0026 17.5 4.0 0.0026 17.5 4.0 1.0 1 0 0 1 1 1 1 Tetraspanin family Innexin PF00876.18 KFP00237.1 - 2.3e-10 40.3 0.5 8.8e-10 38.4 0.3 1.9 1 1 1 2 2 2 1 Innexin DUF2207 PF09972.9 KFP00237.1 - 0.004 16.0 0.0 0.006 15.4 0.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Ecl1 PF12855.7 KFP00237.1 - 0.028 15.6 0.5 0.028 15.6 0.5 2.4 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins AAA_12 PF13087.6 KFP00238.1 - 7.3e-44 149.8 0.0 2e-43 148.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KFP00238.1 - 1.8e-34 119.7 0.0 2.4e-17 63.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KFP00238.1 - 5.3e-15 55.6 0.0 1e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain S1-like PF14444.6 KFP00238.1 - 1.3e-13 50.7 0.6 4.2e-05 23.4 0.9 3.8 3 0 0 3 3 3 3 S1-like AAA_19 PF13245.6 KFP00238.1 - 4e-08 33.7 0.0 1e-07 32.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KFP00238.1 - 0.00025 21.1 0.0 0.00075 19.5 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KFP00238.1 - 0.00037 20.3 0.1 0.51 10.0 0.0 3.1 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 KFP00238.1 - 0.0038 17.0 0.4 0.033 14.0 0.1 2.6 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain DEAD PF00270.29 KFP00238.1 - 0.014 15.2 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase UvrD-helicase PF00580.21 KFP00238.1 - 0.015 14.8 0.0 2.8 7.4 0.0 2.4 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain PhoH PF02562.16 KFP00238.1 - 0.018 14.5 0.0 0.23 10.9 0.0 2.2 1 1 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 KFP00238.1 - 0.037 14.3 0.0 0.2 11.9 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KFP00238.1 - 0.15 12.5 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.14 KFP00238.1 - 0.16 11.1 0.0 15 4.6 0.0 2.4 2 0 0 2 2 2 0 PIF1-like helicase AAA_16 PF13191.6 KFP00238.1 - 0.18 12.2 0.0 0.37 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain KASH PF10541.9 KFP00239.1 - 0.1 12.9 5.3 1.4 9.2 0.1 2.7 2 0 0 2 2 2 0 Nuclear envelope localisation domain IL17_R_N PF15037.6 KFP00240.1 - 1.8e-36 126.0 10.5 1.2e-35 123.2 10.5 1.9 1 1 0 1 1 1 1 Interleukin-17 receptor extracellular region EGF_CA PF07645.15 KFP00242.1 - 1.1e-14 54.4 27.0 2.2e-10 40.6 11.8 7.2 4 2 2 6 6 6 2 Calcium-binding EGF domain DUF3456 PF11938.8 KFP00242.1 - 1.5e-05 25.6 6.5 0.00026 21.5 1.7 3.2 3 1 1 4 4 4 2 TLR4 regulator and MIR-interacting MSAP EGF PF00008.27 KFP00242.1 - 0.0015 18.8 1.8 0.0015 18.8 1.8 6.7 8 1 1 9 9 9 3 EGF-like domain Plasmod_Pvs28 PF06247.11 KFP00242.1 - 0.0019 18.5 10.5 0.0019 18.5 10.5 5.6 2 2 2 4 4 4 1 Pvs28 EGF domain hEGF PF12661.7 KFP00242.1 - 0.0032 18.1 1.3 0.0032 18.1 1.3 7.8 7 2 0 7 7 7 1 Human growth factor-like EGF VSP PF03302.13 KFP00242.1 - 0.0033 16.3 63.1 0.26 10.1 30.3 3.2 1 1 1 2 2 2 2 Giardia variant-specific surface protein EGF_MSP1_1 PF12946.7 KFP00242.1 - 0.02 14.9 4.0 0.02 14.9 4.0 5.3 4 1 1 5 5 5 0 MSP1 EGF domain 1 Glyco_transf_22 PF03901.17 KFP00243.1 - 3.7e-44 151.6 30.4 4.4e-44 151.4 30.4 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family zf-BED PF02892.15 KFP00244.1 - 7.7e-64 211.5 29.6 1.8e-16 59.9 0.4 4.8 4 0 0 4 4 4 4 BED zinc finger Dimer_Tnp_hAT PF05699.14 KFP00244.1 - 7.8e-11 41.6 3.8 1.1e-10 41.1 0.6 2.9 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region PyrI_C PF02748.15 KFP00244.1 - 6.5e-05 22.8 5.0 2.5 8.1 0.1 4.5 4 0 0 4 4 4 3 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_12 PF18658.1 KFP00244.1 - 0.11 12.0 11.9 1.2 8.8 0.1 4.3 4 0 0 4 4 4 0 Zinc-finger C2H2-type zinc_ribbon_9 PF14369.6 KFP00244.1 - 5.6 7.3 9.1 41 4.6 0.0 3.9 4 0 0 4 4 4 0 zinc-ribbon zf-HC5HC2H_2 PF13832.6 KFP00245.1 - 4.3e-37 126.6 4.5 4.3e-37 126.6 4.5 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 KFP00245.1 - 4.1e-34 118.2 2.1 4.1e-34 118.2 2.1 2.5 3 1 0 3 3 3 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 KFP00245.1 - 3.4e-26 91.3 2.9 3.4e-26 91.3 2.9 3.5 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.25 KFP00245.1 - 2.2e-25 88.5 0.4 5.4e-25 87.3 0.4 1.7 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.17 KFP00245.1 - 4.1e-18 65.6 0.0 2.3e-17 63.2 0.0 2.4 1 0 0 1 1 1 1 PWWP domain PHD_2 PF13831.6 KFP00245.1 - 1.9e-13 49.7 4.4 1.9e-13 49.7 4.4 2.9 2 1 0 2 2 2 1 PHD-finger PHD PF00628.29 KFP00245.1 - 6.5e-07 29.1 27.9 2.7e-06 27.2 13.4 2.9 2 0 0 2 2 2 2 PHD-finger AAA_23 PF13476.6 KFP00245.1 - 0.011 16.2 8.2 0.035 14.6 1.2 2.9 3 0 0 3 3 3 0 AAA domain DUF3439 PF11921.8 KFP00245.1 - 0.074 13.0 1.4 0.26 11.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DNA_topoisoIV PF00521.20 KFP00245.1 - 0.18 10.7 4.8 0.35 9.7 4.8 1.4 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A TAFA PF12020.8 KFP00246.1 - 1.4e-44 150.5 9.9 1.6e-44 150.3 9.9 1.0 1 0 0 1 1 1 1 TAFA family Yae1_N PF09811.9 KFP00247.1 - 6e-16 57.9 48.2 0.0014 18.2 8.4 4.8 1 1 2 3 3 3 3 Essential protein Yae1, N terminal RabGAP-TBC PF00566.18 KFP00248.1 - 2.1e-50 171.4 1.9 2.1e-50 171.4 1.9 1.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain ELMO_CED12 PF04727.13 KFP00248.1 - 0.14 12.2 1.4 0.2 11.7 0.1 1.9 2 0 0 2 2 2 0 ELMO/CED-12 family DAGK_cat PF00781.24 KFP00249.1 - 3.1e-19 68.8 0.0 6.3e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain RVT_1 PF00078.27 KFP00250.1 - 0.0003 20.4 0.0 0.00047 19.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Histone PF00125.24 KFP00251.1 - 5.6e-26 91.4 0.4 7.2e-26 91.1 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFP00251.1 - 9.1e-07 29.1 0.7 1.8e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KFP00251.1 - 0.0034 17.8 0.0 0.006 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KFP00251.1 - 0.0047 17.0 0.3 0.0055 16.7 0.3 1.2 1 0 0 1 1 1 1 YscO-like protein GTSE1_N PF15259.6 KFP00252.1 - 1.2e-55 187.7 0.6 1.2e-55 187.7 0.6 2.6 3 1 0 3 3 3 1 G-2 and S-phase expressed 1 CGI-121 PF08617.10 KFP00253.1 - 3.9e-44 150.6 1.3 4.4e-44 150.5 1.3 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Exonuc_VII_S PF02609.16 KFP00253.1 - 0.11 12.6 0.4 0.28 11.3 0.4 1.6 1 0 0 1 1 1 0 Exonuclease VII small subunit DIE2_ALG10 PF04922.12 KFP00254.1 - 1.2e-128 429.8 29.4 1.4e-128 429.6 29.4 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Copine PF07002.16 KFP00255.1 - 3.2e-89 298.1 0.0 4.3e-89 297.7 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 KFP00255.1 - 1.8e-27 95.6 0.1 2.7e-14 53.3 0.1 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 KFP00255.1 - 3.9e-07 30.4 0.0 6.9e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus Glyco_hydro_31 PF01055.26 KFP00256.1 - 3.3e-153 511.0 2.0 4.4e-153 510.6 2.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KFP00256.1 - 4.8e-29 100.9 0.8 9.5e-29 99.9 0.8 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KFP00256.1 - 3.1e-07 30.6 0.3 1.6e-06 28.4 0.1 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KFP00256.1 - 0.13 12.6 0.1 0.44 10.9 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) ABC_membrane_2 PF06472.15 KFP00257.1 - 1.1e-100 336.5 5.0 1.5e-100 336.1 5.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KFP00257.1 - 1.9e-18 67.3 0.0 3.8e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFP00257.1 - 8.2e-05 22.6 0.0 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFP00257.1 - 0.00071 20.1 0.2 0.0036 17.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFP00257.1 - 0.0048 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Cyto_heme_lyase PF01265.17 KFP00257.1 - 0.01 15.5 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase Rad17 PF03215.15 KFP00257.1 - 0.011 15.7 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain SMC_N PF02463.19 KFP00257.1 - 0.021 14.3 0.0 0.21 11.0 0.1 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Adeno_IVa2 PF02456.15 KFP00257.1 - 0.024 13.4 0.1 0.042 12.6 0.1 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein SseC PF04888.12 KFP00257.1 - 0.033 13.8 0.0 0.08 12.5 0.0 1.5 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family ARID PF01388.21 KFP00257.1 - 0.042 14.5 0.1 0.13 12.9 0.1 1.8 1 0 0 1 1 1 0 ARID/BRIGHT DNA binding domain AAA_16 PF13191.6 KFP00257.1 - 0.13 12.6 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Sugar_tr PF00083.24 KFP00258.1 - 1.1e-93 314.6 12.7 4.1e-69 233.6 1.9 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFP00258.1 - 1.7e-15 56.8 23.3 2.2e-12 46.6 12.4 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Ral PF11058.8 KFP00258.1 - 0.042 13.4 1.0 0.081 12.5 1.0 1.4 1 0 0 1 1 1 0 Antirestriction protein Ral PSI_integrin PF17205.3 KFP00258.1 - 1.6 8.5 5.7 3.2 7.6 5.7 1.5 1 0 0 1 1 1 0 Integrin plexin domain Pkinase PF00069.25 KFP00259.1 - 2.6e-40 138.5 0.0 7.4e-40 137.0 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP00259.1 - 1.1e-39 136.3 0.0 3.5e-39 134.7 0.0 1.8 2 0 0 2 2 1 1 Protein tyrosine kinase Roc PF08477.13 KFP00259.1 - 2.3e-31 108.5 0.1 6.5e-31 107.1 0.1 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase LRR_8 PF13855.6 KFP00259.1 - 5.1e-27 93.4 40.6 6.8e-07 29.0 2.6 6.8 4 1 1 6 6 6 5 Leucine rich repeat COR PF16095.5 KFP00259.1 - 2.1e-26 92.9 0.7 4e-25 88.8 0.4 2.5 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain LRR_4 PF12799.7 KFP00259.1 - 6.9e-20 70.8 49.5 3.7e-07 30.4 0.1 8.8 4 2 3 9 9 8 7 Leucine Rich repeats (2 copies) Ras PF00071.22 KFP00259.1 - 1e-15 57.7 0.0 2.5e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KFP00259.1 - 1.6e-07 30.9 1.0 2.9e-07 30.1 0.1 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Ank_2 PF12796.7 KFP00259.1 - 4.2e-05 24.0 1.8 0.0001 22.8 0.3 2.5 2 0 0 2 2 1 1 Ankyrin repeats (3 copies) Gtr1_RagA PF04670.12 KFP00259.1 - 0.00016 21.1 0.0 0.00034 20.0 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region LRR_9 PF14580.6 KFP00259.1 - 0.00026 20.5 13.5 0.02 14.4 1.6 4.0 1 1 4 5 5 5 2 Leucine-rich repeat ABC_tran PF00005.27 KFP00259.1 - 0.0033 17.9 0.2 0.011 16.2 0.2 1.9 1 0 0 1 1 1 1 ABC transporter NB-ARC PF00931.22 KFP00259.1 - 0.011 14.9 0.5 0.059 12.6 0.5 2.2 1 1 0 1 1 1 0 NB-ARC domain T2SSE PF00437.20 KFP00259.1 - 0.014 14.5 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PduV-EutP PF10662.9 KFP00259.1 - 0.015 15.1 0.5 0.04 13.7 0.5 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TrwB_AAD_bind PF10412.9 KFP00259.1 - 0.019 13.9 0.4 0.047 12.6 0.1 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.23 KFP00259.1 - 0.02 14.9 0.0 0.056 13.5 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.20 KFP00259.1 - 0.028 13.6 0.6 0.058 12.5 0.1 1.8 2 0 0 2 2 2 0 G-protein alpha subunit Septin PF00735.18 KFP00259.1 - 0.028 13.7 0.1 0.054 12.8 0.1 1.4 1 0 0 1 1 1 0 Septin Ank_4 PF13637.6 KFP00259.1 - 0.03 14.9 0.4 0.49 11.1 0.0 3.4 3 1 1 4 4 2 0 Ankyrin repeats (many copies) cobW PF02492.19 KFP00259.1 - 0.03 13.9 0.4 0.07 12.7 0.4 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KFP00259.1 - 0.03 13.8 0.1 0.061 12.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KFP00259.1 - 0.032 14.5 0.0 0.18 12.1 0.0 2.4 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 KFP00259.1 - 0.036 14.0 1.8 0.082 12.8 0.4 2.3 2 0 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.18 KFP00259.1 - 0.043 13.2 0.0 0.091 12.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Kdo PF06293.14 KFP00259.1 - 0.054 12.8 0.1 0.15 11.4 0.1 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_16 PF13191.6 KFP00259.1 - 0.056 13.8 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KFP00259.1 - 0.079 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KFP00259.1 - 0.1 12.8 0.0 0.28 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain LRR_6 PF13516.6 KFP00259.1 - 0.17 12.1 41.4 4.2 7.7 0.1 10.4 11 0 0 11 11 10 0 Leucine Rich repeat MobB PF03205.14 KFP00259.1 - 0.17 11.8 1.2 0.26 11.2 0.3 1.8 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.6 KFP00259.1 - 0.5 10.8 0.0 0.5 10.8 0.0 3.5 4 0 0 4 4 3 0 AAA domain Arm PF00514.23 KFP00259.1 - 0.56 10.3 6.9 0.093 12.8 0.1 3.3 4 0 0 4 4 2 0 Armadillo/beta-catenin-like repeat COPIIcoated_ERV PF07970.12 KFP00260.1 - 6.5e-50 170.0 0.3 9.6e-50 169.5 0.3 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KFP00260.1 - 2.3e-24 85.5 0.3 5.6e-24 84.3 0.3 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pyr_redox_2 PF07992.14 KFP00261.1 - 5e-64 216.4 7.6 5e-64 216.4 7.6 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFP00261.1 - 1.2e-41 141.4 0.8 3.9e-41 139.7 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFP00261.1 - 9.2e-18 64.6 7.7 1.1e-16 61.2 1.0 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFP00261.1 - 6.7e-11 42.0 2.7 4.7e-10 39.2 2.7 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFP00261.1 - 1.4e-09 37.5 1.9 9.3e-07 28.3 0.3 3.0 3 0 0 3 3 3 2 FAD binding domain FAD_oxidored PF12831.7 KFP00261.1 - 3.5e-09 36.5 0.2 3.5e-09 36.5 0.2 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFP00261.1 - 1.4e-07 31.7 1.5 5.1e-05 23.4 0.1 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KFP00261.1 - 5e-06 25.8 10.1 1e-05 24.9 3.9 2.9 2 1 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KFP00261.1 - 3.1e-05 23.4 5.9 0.033 13.5 0.9 2.8 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 KFP00261.1 - 8.7e-05 21.8 2.1 0.16 11.1 0.3 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KFP00261.1 - 8.7e-05 21.9 4.6 0.0067 15.7 0.2 3.4 4 0 0 4 4 4 1 FAD binding domain HI0933_like PF03486.14 KFP00261.1 - 0.00012 20.9 11.3 0.0016 17.2 0.5 3.7 4 0 0 4 4 4 2 HI0933-like protein Thi4 PF01946.17 KFP00261.1 - 0.00014 21.2 0.1 0.00014 21.2 0.1 1.9 2 1 0 2 2 2 1 Thi4 family UDPG_MGDP_dh_N PF03721.14 KFP00261.1 - 0.0016 18.1 4.9 1.2 8.7 0.1 3.6 4 0 0 4 4 4 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UPF0227 PF05728.12 KFP00261.1 - 0.12 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) 3HCDH_N PF02737.18 KFP00261.1 - 0.14 12.1 4.9 1.3 8.9 0.7 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KFP00261.1 - 0.39 10.1 2.0 2.9 7.2 0.3 2.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 KFP00261.1 - 0.45 10.0 13.4 3.4 7.1 0.5 4.0 3 1 0 4 4 4 0 FAD dependent oxidoreductase Sulfate_transp PF00916.20 KFP00262.1 - 5.1e-111 371.1 23.9 6.6e-111 370.7 23.9 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFP00262.1 - 3.5e-34 116.9 0.1 6.3e-34 116.1 0.1 1.5 1 0 0 1 1 1 1 STAS domain zf_Hakai PF18408.1 KFP00263.1 - 2.5e-21 75.1 2.3 5e-21 74.1 2.3 1.5 1 0 0 1 1 1 1 C2H2 Hakai zinc finger domain zf-C3HC4_3 PF13920.6 KFP00263.1 - 2.5e-05 24.0 7.9 5.2e-05 23.0 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP00263.1 - 0.0012 18.7 7.5 0.0027 17.6 7.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFP00263.1 - 0.0012 18.6 8.7 0.0027 17.6 8.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP00263.1 - 0.0016 18.3 9.6 0.0066 16.3 9.6 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP00263.1 - 0.019 14.8 6.5 0.043 13.7 6.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DZR PF12773.7 KFP00263.1 - 0.043 13.8 7.2 0.21 11.6 7.0 2.1 1 1 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 KFP00263.1 - 0.053 13.5 10.4 0.1 12.6 10.4 1.4 1 0 0 1 1 1 0 zinc-ribbons zf-RING_2 PF13639.6 KFP00263.1 - 0.069 13.5 8.5 0.17 12.3 8.5 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 KFP00263.1 - 0.12 12.4 6.8 0.37 10.8 6.8 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 KFP00263.1 - 0.78 9.6 8.1 0.1 12.4 3.7 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.20 KFP00263.1 - 0.83 9.5 5.6 1.9 8.3 5.6 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger C1_4 PF07975.12 KFP00263.1 - 5.9 7.2 10.1 7.3 6.9 8.5 2.0 2 1 0 2 2 2 0 TFIIH C1-like domain Bap31 PF05529.12 KFP00264.1 - 1.1e-30 106.2 15.0 5.1e-22 78.2 4.5 2.8 1 1 2 3 3 3 2 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KFP00264.1 - 4.3e-13 49.0 6.9 4.3e-13 49.0 6.9 2.6 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain MPS2 PF17060.5 KFP00264.1 - 6.3e-05 22.4 7.2 6.3e-05 22.4 7.2 1.4 2 0 0 2 2 2 1 Monopolar spindle protein 2 MscS_porin PF12795.7 KFP00264.1 - 0.0016 18.1 12.0 0.0021 17.6 12.0 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain MAD PF05557.13 KFP00264.1 - 0.0017 16.8 14.5 0.002 16.6 14.5 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein APG6_N PF17675.1 KFP00264.1 - 0.0056 17.2 17.3 0.0086 16.6 17.3 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF3810 PF12725.7 KFP00264.1 - 0.0059 16.0 1.4 0.0081 15.5 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3810) CENP-H PF05837.12 KFP00264.1 - 0.0073 16.7 15.8 0.0091 16.4 10.3 2.1 1 1 1 2 2 2 2 Centromere protein H (CENP-H) Sec34 PF04136.15 KFP00264.1 - 0.0088 15.9 7.8 0.024 14.5 2.0 2.2 2 0 0 2 2 2 1 Sec34-like family AAA_13 PF13166.6 KFP00264.1 - 0.012 14.3 6.4 0.014 14.0 6.4 1.1 1 0 0 1 1 1 0 AAA domain AATF-Che1 PF13339.6 KFP00264.1 - 0.013 16.2 7.7 0.021 15.5 7.7 1.3 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF3611 PF12263.8 KFP00264.1 - 0.014 15.3 0.9 0.024 14.5 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) Cluap1 PF10234.9 KFP00264.1 - 0.024 14.1 8.4 0.033 13.6 8.4 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 Sec2p PF06428.11 KFP00264.1 - 0.028 14.4 14.3 0.045 13.7 7.3 2.3 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p YabA PF06156.13 KFP00264.1 - 0.034 14.8 14.8 0.049 14.3 3.7 2.4 2 1 1 3 3 2 0 Initiation control protein YabA DUF1664 PF07889.12 KFP00264.1 - 0.039 14.0 4.9 0.074 13.1 4.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF1993 PF09351.10 KFP00264.1 - 0.045 13.9 1.6 0.066 13.3 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) ADIP PF11559.8 KFP00264.1 - 0.049 13.7 13.5 0.069 13.2 13.5 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF2228 PF10228.9 KFP00264.1 - 0.05 13.3 3.7 0.063 13.0 3.7 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) Apolipoprotein PF01442.18 KFP00264.1 - 0.057 13.3 13.4 0.077 12.9 13.4 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain HOOK PF05622.12 KFP00264.1 - 0.06 11.5 13.9 0.076 11.2 13.9 1.1 1 0 0 1 1 1 0 HOOK protein KASH_CCD PF14662.6 KFP00264.1 - 0.07 13.0 15.4 0.1 12.4 15.4 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF4878 PF12870.7 KFP00264.1 - 0.091 13.1 8.0 0.17 12.2 8.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) Uso1_p115_C PF04871.13 KFP00264.1 - 0.1 13.0 18.4 0.15 12.4 18.4 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region HIP1_clath_bdg PF16515.5 KFP00264.1 - 0.12 13.0 13.2 0.22 12.2 13.2 1.5 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Cnn_1N PF07989.11 KFP00264.1 - 0.2 11.8 13.1 0.38 10.9 11.7 2.2 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Uds1 PF15456.6 KFP00264.1 - 0.23 11.6 11.1 0.41 10.8 11.1 1.4 1 0 0 1 1 1 0 Up-regulated During Septation FapA PF03961.13 KFP00264.1 - 0.42 9.2 8.8 0.53 8.8 8.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIVA PF05103.13 KFP00264.1 - 0.72 9.9 13.3 1.2 9.2 13.3 1.3 1 0 0 1 1 1 0 DivIVA protein Spc7 PF08317.11 KFP00264.1 - 0.75 8.6 14.9 1.1 8.1 14.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein IFP_35_N PF07334.13 KFP00264.1 - 1.2 9.3 6.9 0.5 10.5 3.8 2.0 1 1 1 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Tho2 PF11262.8 KFP00264.1 - 1.2 8.2 8.6 1.8 7.7 8.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Syntaxin_2 PF14523.6 KFP00264.1 - 1.4 9.3 8.8 4.3 7.8 8.8 1.8 1 1 0 1 1 1 0 Syntaxin-like protein Seryl_tRNA_N PF02403.22 KFP00264.1 - 2 8.7 14.6 4.2 7.6 14.5 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF948 PF06103.11 KFP00264.1 - 3.1 8.1 10.8 1.1e+03 -0.1 10.8 3.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) UPF0242 PF06785.11 KFP00264.1 - 3.8 7.6 17.7 39 4.3 17.7 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cep57_CLD_2 PF14197.6 KFP00264.1 - 4.1 7.6 13.7 81 3.4 13.8 2.8 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 CC2-LZ PF16516.5 KFP00264.1 - 5.4 7.5 14.6 1.9 8.9 5.4 2.3 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator OmpH PF03938.14 KFP00264.1 - 6.2 7.2 19.1 32 4.9 19.1 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) ZapB PF06005.12 KFP00264.1 - 6.3 7.3 20.0 7 7.2 9.4 2.5 1 1 1 2 2 2 0 Cell division protein ZapB DUF4407 PF14362.6 KFP00264.1 - 7.8 5.7 15.8 0.039 13.3 7.5 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4407) Dus PF01207.17 KFP00265.1 - 1.3e-73 247.8 0.1 1.6e-73 247.5 0.1 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KFP00265.1 - 1.9e-05 24.3 0.3 0.0077 15.7 0.0 1.5 1 1 1 2 2 2 2 Histidine biosynthesis protein TMP-TENI PF02581.17 KFP00265.1 - 0.0053 16.1 0.0 0.01 15.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase Oxidored_FMN PF00724.20 KFP00265.1 - 0.049 12.9 0.0 0.093 12.0 0.0 1.5 1 1 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family ThiG PF05690.14 KFP00265.1 - 0.053 12.8 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG DUF3791 PF12668.7 KFP00265.1 - 0.11 12.6 0.0 0.45 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) DUF561 PF04481.12 KFP00265.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF561) COG5 PF10392.9 KFP00266.1 - 1.5e-30 106.1 4.5 1.5e-30 106.1 4.5 2.5 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.11 KFP00266.1 - 2.6e-09 37.0 1.1 2.6e-09 37.0 1.1 3.3 3 1 1 4 4 4 1 Vps51/Vps67 COG2 PF06148.11 KFP00266.1 - 4.8e-05 23.4 1.1 4.8e-05 23.4 1.1 3.6 4 1 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3135 PF11333.8 KFP00266.1 - 0.022 15.0 0.2 0.099 12.9 0.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) FapA PF03961.13 KFP00266.1 - 0.071 11.7 0.4 0.83 8.2 0.0 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A Vps54_N PF10475.9 KFP00266.1 - 0.27 10.5 6.5 0.088 12.1 2.1 2.1 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex THOC7 PF05615.13 KFP00266.1 - 0.85 9.9 4.4 8.5 6.7 1.1 3.7 3 0 0 3 3 3 0 Tho complex subunit 7 Fib_alpha PF08702.10 KFP00266.1 - 0.87 9.8 4.8 2.4 8.4 1.2 3.3 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Sec8_exocyst PF04048.14 KFP00266.1 - 1.6 8.7 5.7 0.85 9.5 0.7 3.2 3 1 1 4 4 4 0 Sec8 exocyst complex component specific domain 7tm_1 PF00001.21 KFP00267.1 - 2.3e-25 89.4 22.7 3e-25 89.0 22.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pex24p PF06398.11 KFP00267.1 - 1.3 8.0 17.1 0.013 14.5 8.2 2.0 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin DUF1980 PF09323.10 KFP00267.1 - 3.9 7.4 12.2 3.1 7.7 0.8 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1980) AXH PF08517.12 KFP00268.1 - 5.5e-35 120.4 0.0 1.1e-34 119.4 0.0 1.5 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) HMG_box PF00505.19 KFP00268.1 - 6.4e-15 55.3 0.9 1.2e-14 54.4 0.9 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP00268.1 - 2.5e-09 37.6 1.6 5.2e-09 36.6 1.6 1.5 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 KFP00268.1 - 0.0024 17.2 0.1 0.0047 16.3 0.1 1.4 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box Peptidase_S64 PF08192.11 KFP00268.1 - 0.042 12.4 2.9 0.065 11.7 2.9 1.2 1 0 0 1 1 1 0 Peptidase family S64 cNMP_binding PF00027.29 KFP00269.1 - 2.3e-37 126.9 0.1 6.3e-20 71.0 0.1 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PI3Ka PF00613.20 KFP00270.1 - 2.3e-63 213.0 1.4 2.3e-63 213.0 1.4 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KFP00270.1 - 2.2e-56 191.4 0.7 2.2e-56 191.4 0.7 2.2 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_rbd PF00794.18 KFP00270.1 - 5e-29 100.6 1.3 1.1e-26 93.1 0.0 3.1 3 0 0 3 3 3 2 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 KFP00270.1 - 5.6e-16 58.7 0.3 1.7e-15 57.2 0.1 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 KFP00270.1 - 0.0037 16.6 0.0 0.0067 15.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) NAPRTase PF04095.16 KFP00271.1 - 2.2e-72 243.6 0.0 3e-72 243.1 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF5598 PF18127.1 KFP00271.1 - 3.3e-36 123.6 3.8 3.5e-36 123.6 2.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5598) MARVEL PF01284.23 KFP00272.1 - 5.9e-34 117.2 15.2 7.5e-34 116.8 15.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain SieB PF14163.6 KFP00272.1 - 0.25 10.8 2.8 0.3 10.6 1.7 1.6 1 1 0 1 1 1 0 Super-infection exclusion protein B SCA7 PF08313.12 KFP00273.1 - 3.7e-28 97.2 4.1 6.7e-28 96.4 2.3 2.3 2 0 0 2 2 2 1 SCA7, zinc-binding domain OrsD PF12013.8 KFP00273.1 - 0.046 14.2 0.6 0.2 12.1 0.6 2.1 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D EF-hand_6 PF13405.6 KFP00274.1 - 0.023 14.6 0.0 0.057 13.4 0.0 1.7 2 0 0 2 2 2 0 EF-hand domain EF-hand_14 PF17959.1 KFP00274.1 - 0.14 12.5 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain RINT1_TIP1 PF04437.13 KFP00275.1 - 5.7e-133 444.4 14.2 5.7e-133 444.4 14.2 2.1 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Muted PF14942.6 KFP00275.1 - 0.78 10.1 5.3 0.2 12.0 1.4 2.0 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF948 PF06103.11 KFP00275.1 - 0.97 9.7 3.2 6.3 7.1 1.5 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Syntaxin_2 PF14523.6 KFP00275.1 - 1.1 9.6 17.4 2.1 8.8 0.1 3.6 2 1 1 3 3 3 0 Syntaxin-like protein TruD PF01142.18 KFP00276.1 - 1.1e-70 238.6 0.0 4.1e-65 220.2 0.0 2.6 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Pkinase PF00069.25 KFP00277.1 - 5.8e-35 120.9 6.2 4.8e-22 78.6 0.2 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFP00277.1 - 1.3e-12 47.6 0.1 5.9e-09 35.6 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP00277.1 - 0.0069 15.2 0.2 0.0069 15.2 0.2 2.1 1 1 0 2 2 2 1 Fungal protein kinase SET PF00856.28 KFP00278.1 - 1.9e-09 38.1 0.7 1.9e-09 38.1 0.7 3.2 3 1 0 3 3 3 1 SET domain PHD PF00628.29 KFP00278.1 - 1.7e-08 34.2 12.1 4.2e-08 32.9 12.1 1.8 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KFP00278.1 - 0.0071 15.9 8.5 0.016 14.8 8.5 1.6 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.6 KFP00278.1 - 0.16 12.4 2.0 1.8 9.0 2.0 3.0 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx ORC5_C PF14630.6 KFP00279.1 - 2.8e-60 204.2 0.4 4.2e-60 203.7 0.0 1.4 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 KFP00279.1 - 2.7e-14 53.9 0.0 5.2e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFP00279.1 - 2e-08 34.6 0.3 9.2e-08 32.5 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KFP00279.1 - 0.0022 17.7 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Kinesin PF00225.23 KFP00279.1 - 0.0033 16.4 0.9 0.0067 15.4 0.6 1.6 1 1 0 1 1 1 1 Kinesin motor domain ATPase_2 PF01637.18 KFP00279.1 - 0.0056 16.6 0.0 0.012 15.6 0.0 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea Microtub_bd PF16796.5 KFP00279.1 - 0.007 16.3 0.2 0.019 14.9 0.1 1.7 1 1 0 1 1 1 1 Microtubule binding AAA_14 PF13173.6 KFP00279.1 - 0.023 14.7 0.9 0.3 11.1 0.8 2.3 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.14 KFP00279.1 - 0.026 13.7 0.0 0.079 12.1 0.0 1.8 2 0 0 2 2 2 0 PIF1-like helicase AAA_7 PF12775.7 KFP00279.1 - 0.065 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 KFP00279.1 - 0.074 13.5 0.0 0.26 11.7 0.0 1.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sulfate_transp PF00916.20 KFP00280.1 - 2.5e-117 391.9 25.1 3.3e-117 391.5 25.1 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFP00280.1 - 2.5e-27 94.8 0.0 4.4e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain AAA PF00004.29 KFP00281.1 - 1.3e-40 138.9 0.0 6.4e-40 136.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFP00281.1 - 7.2e-09 35.3 0.1 1.9e-08 34.0 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KFP00281.1 - 5.6e-05 23.4 0.0 0.0058 16.9 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KFP00281.1 - 0.00041 20.4 0.1 0.0023 17.9 0.1 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFP00281.1 - 0.0018 18.7 0.5 0.027 14.8 0.1 2.5 2 1 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.14 KFP00281.1 - 0.0035 17.5 0.0 0.012 15.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KFP00281.1 - 0.0038 16.4 0.0 0.013 14.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KFP00281.1 - 0.0078 16.0 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KFP00281.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFP00281.1 - 0.014 15.6 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFP00281.1 - 0.017 15.6 0.0 0.052 14.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 KFP00281.1 - 0.021 14.4 0.0 0.049 13.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 KFP00281.1 - 0.064 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 KFP00281.1 - 0.064 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KFP00281.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 KFP00281.1 - 0.077 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 KFP00281.1 - 0.081 12.6 0.3 0.66 9.7 0.0 2.5 3 1 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 KFP00281.1 - 0.098 13.1 0.0 0.32 11.4 0.0 1.9 2 0 0 2 2 1 0 RNA helicase ATPase_2 PF01637.18 KFP00281.1 - 0.13 12.2 0.2 27 4.6 0.0 3.0 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_3 PF07726.11 KFP00281.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KFP00281.1 - 0.15 12.1 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KFP00281.1 - 0.17 11.6 0.0 0.45 10.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain RAC_head PF16717.5 KFP00282.1 - 5.6e-23 81.8 8.4 5.6e-23 81.8 8.4 4.3 4 2 0 4 4 4 1 Ribosome-associated complex head domain Myb_DNA-binding PF00249.31 KFP00282.1 - 2.2e-20 72.5 0.2 1.4e-11 44.4 0.1 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain DnaJ PF00226.31 KFP00282.1 - 3.3e-15 56.0 0.1 3.3e-15 56.0 0.1 2.8 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-bind_6 PF13921.6 KFP00282.1 - 3e-10 40.2 1.2 7e-06 26.2 0.1 3.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain GHBP PF12772.7 KFP00282.1 - 2.5 7.5 15.9 0.87 9.1 11.8 2.5 1 1 1 2 2 2 0 Growth hormone receptor binding Peptidase_M16 PF00675.20 KFP00283.1 - 2.1e-56 190.1 0.2 3.1e-56 189.5 0.2 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFP00283.1 - 1.3e-38 132.9 0.0 8.1e-38 130.3 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain Lactamase_B_2 PF12706.7 KFP00284.1 - 8.3e-38 129.9 0.0 1.2e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KFP00284.1 - 7.2e-14 52.0 0.0 1.1e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KFP00284.1 - 0.0064 16.5 0.0 0.025 14.6 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Arm_2 PF04826.13 KFP00285.1 - 1.7e-68 230.8 7.9 1.9e-68 230.7 7.9 1.0 1 0 0 1 1 1 1 Armadillo-like Arm PF00514.23 KFP00285.1 - 5.4e-08 32.6 2.9 0.011 15.7 0.0 3.5 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KFP00285.1 - 0.0028 17.8 0.2 0.87 10.0 0.0 3.2 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 KFP00285.1 - 0.0068 16.8 0.2 5.4 7.5 0.1 2.6 2 1 0 2 2 2 2 HEAT repeats Cnd3 PF12719.7 KFP00285.1 - 0.015 14.5 1.1 0.045 13.0 0.7 1.9 1 1 1 2 2 2 0 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 KFP00285.1 - 0.04 14.4 0.6 20 5.8 0.0 3.0 3 1 1 4 4 4 0 HEAT-like repeat Atx10homo_assoc PF09759.9 KFP00285.1 - 0.14 12.2 1.7 0.67 10.0 1.0 2.3 1 1 1 2 2 2 0 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.8 KFP00285.1 - 0.35 10.8 3.9 0.6 10.0 1.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3361) LRR_6 PF13516.6 KFP00286.1 - 3.1e-28 95.4 23.1 0.28 11.4 0.0 14.5 15 0 0 15 15 15 9 Leucine Rich repeat LRR_4 PF12799.7 KFP00286.1 - 1.6e-18 66.4 12.8 0.023 15.1 0.1 8.9 5 3 4 10 10 10 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP00286.1 - 8.5e-10 38.3 6.9 0.013 15.3 3.9 6.8 6 1 1 7 7 7 2 Leucine rich repeat F-box-like PF12937.7 KFP00286.1 - 2.9e-06 27.0 0.8 8.7e-06 25.5 0.1 2.3 2 0 0 2 2 2 1 F-box-like LRR_1 PF00560.33 KFP00286.1 - 5e-06 26.3 17.8 3.4 8.6 0.1 11.5 14 0 0 14 14 14 1 Leucine Rich Repeat F-box PF00646.33 KFP00286.1 - 0.00013 21.8 0.0 0.00053 19.8 0.0 2.2 1 0 0 1 1 1 1 F-box domain SAM_Ste50p PF09235.10 KFP00286.1 - 0.027 14.7 11.4 10 6.4 0.0 5.7 6 0 0 6 6 6 0 Ste50p, sterile alpha motif Endothelin PF00322.17 KFP00286.1 - 0.69 9.6 3.4 1.7 8.3 2.0 2.5 2 0 0 2 2 2 0 Endothelin family LRR_8 PF13855.6 KFP00287.1 - 1.4e-44 149.6 44.4 3.4e-14 52.4 3.1 4.2 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KFP00287.1 - 5.7e-14 52.0 24.1 4e-05 23.9 5.8 4.8 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP00287.1 - 6.9e-13 48.7 0.3 1.8e-06 27.9 0.2 2.3 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP00287.1 - 1.6e-12 47.2 6.5 1.2e-05 24.9 0.2 2.5 2 1 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFP00287.1 - 0.0005 20.2 17.7 4.1 8.3 0.6 7.0 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.6 KFP00287.1 - 0.00064 19.6 13.4 15 6.0 0.0 5.7 5 0 0 5 5 5 2 Leucine Rich repeat LRRCT PF01463.24 KFP00287.1 - 0.026 15.1 0.0 3.3 8.5 0.0 2.9 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain DUF4097 PF13349.6 KFP00288.1 - 3e-09 36.6 12.3 1.4e-06 27.9 12.3 2.4 1 1 0 1 1 1 1 Putative adhesin BON PF04972.17 KFP00288.1 - 0.037 14.3 2.1 1.5e+02 2.8 0.0 5.0 5 1 1 6 6 6 0 BON domain DUF2807 PF10988.8 KFP00288.1 - 0.068 13.0 5.3 0.086 12.6 0.9 2.7 2 2 1 3 3 3 0 Putative auto-transporter adhesin, head GIN domain HMA PF00403.26 KFP00288.1 - 0.073 13.5 0.6 0.75 10.3 0.1 2.4 2 0 0 2 2 2 0 Heavy-metal-associated domain Fibrinogen_C PF00147.18 KFP00289.1 - 1.6e-89 299.5 9.0 2.1e-89 299.1 9.0 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain FlaC_arch PF05377.11 KFP00289.1 - 0.0048 17.3 3.9 0.0076 16.6 1.2 2.3 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) COLFI PF01410.18 KFP00289.1 - 0.0068 15.7 0.2 0.014 14.7 0.1 1.6 1 1 0 1 1 1 1 Fibrillar collagen C-terminal domain BORCS6 PF10157.9 KFP00289.1 - 0.025 14.8 2.7 0.044 14.0 2.7 1.4 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 NBP1 PF08537.10 KFP00289.1 - 0.11 11.9 6.4 0.2 11.0 6.4 1.4 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Med9 PF07544.13 KFP00289.1 - 0.21 11.7 3.3 0.19 11.8 0.2 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Laminin_II PF06009.12 KFP00289.1 - 0.3 11.1 6.7 0.14 12.2 3.4 1.9 2 0 0 2 2 2 0 Laminin Domain II Exonuc_VII_L PF02601.15 KFP00289.1 - 0.32 10.5 3.0 0.48 10.0 3.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Jnk-SapK_ap_N PF09744.9 KFP00289.1 - 0.59 10.3 6.7 1 9.6 6.7 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 KFP00289.1 - 0.75 9.8 3.0 1.3 9.1 0.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Uds1 PF15456.6 KFP00289.1 - 0.81 9.9 5.1 1.6 8.9 5.1 1.4 1 0 0 1 1 1 0 Up-regulated During Septation Prefoldin PF02996.17 KFP00289.1 - 1.6 8.7 6.7 8.1 6.4 1.0 2.4 2 0 0 2 2 2 0 Prefoldin subunit XhlA PF10779.9 KFP00289.1 - 3.5 7.9 5.6 0.64 10.3 1.5 1.9 2 0 0 2 2 2 0 Haemolysin XhlA Csm1_N PF18504.1 KFP00289.1 - 7.5 7.0 8.5 8.8 6.7 1.0 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain LPP PF04728.13 KFP00289.1 - 9.6 6.7 7.0 6 7.3 0.5 2.8 3 0 0 3 3 2 0 Lipoprotein leucine-zipper GSAP-16 PF14959.6 KFP00290.1 - 1.4e-40 137.5 0.1 4.7e-40 135.8 0.1 2.0 1 0 0 1 1 1 1 gamma-Secretase-activating protein C-term Y_phosphatase PF00102.27 KFP00291.1 - 1e-81 274.0 0.2 1.5e-81 273.5 0.2 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFP00291.1 - 5.5e-05 23.3 0.0 9.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KFP00291.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain UBN_AB PF14075.6 KFP00291.1 - 0.026 14.3 0.4 0.049 13.4 0.4 1.4 1 0 0 1 1 1 0 Ubinuclein conserved middle domain JmjC PF02373.22 KFP00292.1 - 0.48 10.9 0.0 0.48 10.9 0.0 2.3 2 1 0 2 2 2 0 JmjC domain, hydroxylase IHABP4_N PF16174.5 KFP00292.1 - 7.9 7.1 17.4 17 6.0 17.4 1.5 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Tmemb_185A PF10269.9 KFP00293.1 - 1.6e-13 50.9 2.9 2.1e-13 50.6 2.9 1.2 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein DUF3522 PF12036.8 KFP00293.1 - 0.0058 16.9 3.3 0.0068 16.7 2.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3522) CoA_binding_3 PF13727.6 KFP00293.1 - 5.3 7.0 12.5 0.14 12.2 5.4 1.8 1 1 1 2 2 2 0 CoA-binding domain Phtf-FEM1B_bdg PF12129.8 KFP00294.1 - 4.4e-63 211.7 0.3 4.4e-63 211.7 0.3 2.2 2 1 1 3 3 3 1 Male germ-cell putative homeodomain transcription factor PDZ PF00595.24 KFP00295.1 - 3e-61 203.8 10.3 3.5e-15 56.1 0.0 5.5 5 0 0 5 5 5 5 PDZ domain PDZ_6 PF17820.1 KFP00295.1 - 1.6e-48 162.4 13.4 5.6e-11 42.1 0.2 5.4 5 0 0 5 5 5 5 PDZ domain PDZ_2 PF13180.6 KFP00295.1 - 2.4e-25 88.7 0.2 4.1e-05 23.8 0.0 5.4 5 0 0 5 5 5 5 PDZ domain MAGI_u1 PF16663.5 KFP00295.1 - 2.8e-24 84.9 2.5 9.2e-24 83.3 2.5 2.0 1 0 0 1 1 1 1 Unstructured region on MAGI WW PF00397.26 KFP00295.1 - 3.5e-16 59.0 7.2 1.7e-09 37.6 0.3 3.2 3 0 0 3 3 3 2 WW domain Guanylate_kin PF00625.21 KFP00295.1 - 1.5e-08 34.5 0.0 2.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase Tricorn_PDZ PF14685.6 KFP00295.1 - 9e-07 28.8 2.5 1.8 8.6 0.0 5.1 5 0 0 5 5 5 2 Tricorn protease PDZ domain MAGI_u5 PF16666.5 KFP00295.1 - 0.00066 19.8 3.0 0.00066 19.8 3.0 4.8 5 0 0 5 5 5 1 Unstructured region on MAGI PDZ_4 PF17816.1 KFP00295.1 - 0.018 15.4 0.0 33 4.9 0.0 3.8 3 0 0 3 3 3 0 PDZ domain G-alpha PF00503.20 KFP00297.1 - 1.7e-119 399.1 3.7 2.2e-119 398.8 3.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFP00297.1 - 9.2e-16 57.8 0.8 1.5e-11 44.1 0.2 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family TniB PF05621.11 KFP00297.1 - 0.0014 18.1 0.1 0.0021 17.5 0.1 1.2 1 0 0 1 1 1 1 Bacterial TniB protein Gtr1_RagA PF04670.12 KFP00297.1 - 0.0015 17.9 1.3 0.65 9.3 0.6 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KFP00297.1 - 0.0023 18.2 2.3 2 8.6 0.2 3.0 1 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KFP00297.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CD36 PF01130.21 KFP00298.1 - 1.5e-141 472.2 0.0 1.7e-141 471.9 0.0 1.0 1 0 0 1 1 1 1 CD36 family Sema PF01403.19 KFP00299.1 - 6.4e-148 493.1 0.0 1e-147 492.4 0.0 1.3 1 0 0 1 1 1 1 Sema domain I-set PF07679.16 KFP00299.1 - 1.1e-05 25.4 0.3 2.8e-05 24.1 0.1 1.9 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP00299.1 - 1.3e-05 25.7 0.1 8.1e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain PSI PF01437.25 KFP00299.1 - 0.00085 19.8 7.5 0.0026 18.3 7.5 1.9 1 0 0 1 1 1 1 Plexin repeat ig PF00047.25 KFP00299.1 - 0.0044 17.1 0.0 0.016 15.4 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP00299.1 - 0.0061 16.7 0.2 0.16 12.2 0.2 3.0 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KFP00299.1 - 0.0075 16.6 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain SPT16 PF08644.11 KFP00299.1 - 0.1 12.8 0.1 0.26 11.5 0.1 1.6 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Kringle PF00051.18 KFP00300.1 - 4e-110 360.3 41.7 2.6e-29 101.4 6.2 4.5 4 0 0 4 4 4 4 Kringle domain Trypsin PF00089.26 KFP00300.1 - 6.3e-48 163.5 0.0 1.2e-47 162.6 0.0 1.5 1 0 0 1 1 1 1 Trypsin PAN_1 PF00024.26 KFP00300.1 - 3.9e-10 39.6 1.1 1.3e-09 37.8 1.1 1.9 1 0 0 1 1 1 1 PAN domain DUF1986 PF09342.11 KFP00300.1 - 0.0012 19.2 0.0 0.0026 18.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) VGCC_alpha2 PF08473.11 KFP00301.1 - 4e-205 681.6 1.0 6.6e-205 680.9 1.0 1.4 1 0 0 1 1 1 1 Neuronal voltage-dependent calcium channel alpha 2acd VWA_N PF08399.11 KFP00301.1 - 2e-40 138.1 0.2 5e-40 136.8 0.2 1.7 1 0 0 1 1 1 1 VWA N-terminal VWA PF00092.28 KFP00301.1 - 6.3e-22 78.7 0.4 1.1e-21 77.8 0.4 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFP00301.1 - 1.5e-13 51.0 0.0 2.5e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFP00301.1 - 8.9e-11 42.4 0.2 2.3e-10 41.1 0.2 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain dCache_1 PF02743.18 KFP00301.1 - 4.8e-10 39.7 8.4 1.1e-09 38.5 0.2 3.6 2 2 0 3 3 3 1 Cache domain vWA-TerF-like PF10138.9 KFP00301.1 - 0.004 17.3 0.3 0.0077 16.4 0.3 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus Sema PF01403.19 KFP00304.1 - 1.4e-147 492.0 0.0 2e-147 491.4 0.0 1.2 1 0 0 1 1 1 1 Sema domain ig PF00047.25 KFP00304.1 - 2.8e-06 27.4 0.0 5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP00304.1 - 0.0001 22.4 0.0 0.00085 19.5 0.0 2.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain PSI PF01437.25 KFP00304.1 - 0.011 16.3 6.6 0.011 16.3 6.6 2.0 2 0 0 2 2 2 0 Plexin repeat Sema PF01403.19 KFP00305.1 - 9.4e-161 535.3 0.0 1.5e-160 534.7 0.0 1.3 1 0 0 1 1 1 1 Sema domain ig PF00047.25 KFP00305.1 - 4.7e-07 29.9 0.0 1.3e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP00305.1 - 1.3e-05 25.4 0.1 4.2e-05 23.7 0.1 1.9 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP00305.1 - 0.0011 19.5 0.0 0.0043 17.6 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP00305.1 - 0.0023 18.2 0.0 0.0094 16.3 0.0 2.1 1 0 0 1 1 1 1 Immunoglobulin domain PSI PF01437.25 KFP00305.1 - 0.0029 18.1 7.0 0.0029 18.1 7.0 2.0 2 0 0 2 2 2 1 Plexin repeat I-set PF07679.16 KFP00305.1 - 0.027 14.5 0.0 0.06 13.4 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_6 PF18452.1 KFP00305.1 - 0.036 13.6 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Sema PF01403.19 KFP00306.1 - 3.3e-165 550.0 0.0 1.2e-163 544.8 0.0 2.1 1 1 1 2 2 2 2 Sema domain ig PF00047.25 KFP00306.1 - 0.00035 20.7 0.0 0.00086 19.4 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP00306.1 - 0.00083 19.4 0.0 0.0021 18.1 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 KFP00306.1 - 0.00086 19.5 0.1 0.24 11.6 0.0 2.6 1 1 1 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP00306.1 - 0.0011 19.6 0.0 0.0029 18.1 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain PSI PF01437.25 KFP00306.1 - 0.0012 19.4 8.6 0.0027 18.2 8.6 1.6 1 0 0 1 1 1 1 Plexin repeat Ig_6 PF18452.1 KFP00306.1 - 0.0068 15.9 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP00306.1 - 0.008 16.5 0.1 0.04 14.3 0.0 2.3 3 0 0 3 3 3 1 Immunoglobulin domain ANF_receptor PF01094.28 KFP00307.1 - 3.3e-104 348.8 0.1 4.2e-104 348.4 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 KFP00307.1 - 1.1e-66 224.9 22.9 2e-66 224.1 22.9 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 KFP00307.1 - 3.2e-13 49.4 11.5 8.6e-13 48.1 11.5 1.8 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.6 KFP00307.1 - 4.2e-09 36.5 0.0 7.6e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Ephrin_rec_like PF07699.13 KFP00308.1 - 2.3e-06 27.3 83.9 0.00039 20.1 7.8 8.9 6 3 4 10 10 10 8 Putative ephrin-receptor like NCD3G PF07562.14 KFP00308.1 - 0.082 12.9 68.8 0.062 13.3 4.9 7.8 7 1 0 7 7 7 0 Nine Cysteines Domain of family 3 GPCR Myb_DNA-binding PF00249.31 KFP00310.1 - 4.9e-32 109.9 13.4 8.1e-20 70.8 0.7 4.4 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFP00310.1 - 4e-16 59.0 5.3 1.6e-09 37.8 0.1 4.5 3 1 2 5 5 5 2 Myb-like DNA-binding domain DUF5591 PF17884.1 KFP00310.1 - 0.0071 16.2 0.4 3.9 7.3 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF5591) DUF3818 PF12825.7 KFP00310.1 - 0.0082 15.2 1.2 0.017 14.2 1.2 1.4 1 1 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) Myb_DNA-bind_4 PF13837.6 KFP00310.1 - 2.7 8.4 9.9 0.13 12.6 0.4 3.4 4 1 1 5 5 5 0 Myb/SANT-like DNA-binding domain DUF2678 PF10856.8 KFP00311.1 - 1.1e-50 170.5 5.9 1.2e-50 170.4 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) Polysacc_synt_C PF14667.6 KFP00311.1 - 4.4e-06 26.8 2.1 5.1e-06 26.6 2.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis C-terminal domain Intg_mem_TP0381 PF09529.10 KFP00311.1 - 0.045 13.3 7.0 0.055 13.0 7.0 1.1 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) DUF2417 PF10329.9 KFP00311.1 - 0.088 12.2 8.4 0.19 11.1 8.4 1.5 1 1 0 1 1 1 0 Region of unknown function (DUF2417) 7TMR-DISM_7TM PF07695.11 KFP00311.1 - 0.95 9.3 12.0 4.8 7.0 12.2 1.7 1 1 0 1 1 1 0 7TM diverse intracellular signalling COPI_assoc PF08507.10 KFP00311.1 - 2.9 8.0 12.8 0.58 10.2 6.5 2.0 1 1 1 2 2 2 0 COPI associated protein Meiosis_expr PF15163.6 KFP00312.1 - 1.1e-37 128.6 10.7 1.3e-37 128.3 10.7 1.1 1 0 0 1 1 1 1 Meiosis-expressed DRMBL PF07522.14 KFP00313.1 - 1.2e-18 67.3 0.0 2.7e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 KFP00313.1 - 0.039 14.0 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily RMMBL PF07521.12 KFP00313.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain SET PF00856.28 KFP00314.1 - 6.9e-22 78.6 0.2 2.3e-21 76.9 0.1 2.0 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 KFP00314.1 - 4.5e-16 59.5 3.9 4.5e-16 59.5 3.9 2.7 3 0 0 3 3 3 1 Pre-SET motif Chromo PF00385.24 KFP00314.1 - 3e-14 52.7 1.8 6e-14 51.7 1.8 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AWS PF17907.1 KFP00314.1 - 0.0098 15.9 1.5 0.0098 15.9 1.5 3.4 3 0 0 3 3 3 1 AWS domain HSP70 PF00012.20 KFP00315.1 - 1.3e-105 353.9 0.1 1.5e-105 353.7 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFP00315.1 - 2.2e-11 43.1 0.0 3.8e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein tRNA_bind_4 PF18490.1 KFP00315.1 - 0.074 12.8 0.1 4.8 6.9 0.0 2.9 3 0 0 3 3 3 0 tRNA-binding domain DUF1151 PF06625.11 KFP00316.1 - 4.7e-43 145.7 24.5 5.8e-43 145.5 24.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1151) DUF4045 PF13254.6 KFP00316.1 - 0.68 9.5 13.0 1.4 8.5 13.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4045) DUF3338 PF11819.8 KFP00317.1 - 2.4e-59 199.2 6.0 2.4e-59 199.2 6.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3338) FERM_M PF00373.18 KFP00317.1 - 1.8e-20 73.5 3.5 3.4e-20 72.6 0.0 2.9 3 0 0 3 3 3 1 FERM central domain FERM_C PF09380.10 KFP00317.1 - 1.6e-09 38.0 0.2 6.8e-09 36.0 0.2 2.1 1 1 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KFP00317.1 - 4e-09 36.3 0.1 1.1e-08 34.9 0.1 1.7 1 0 0 1 1 1 1 FERM N-terminal domain Prp18 PF02840.15 KFP00318.1 - 1.3e-62 210.0 0.1 2.5e-62 209.2 0.1 1.5 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.11 KFP00318.1 - 2.9e-13 49.1 3.4 2.9e-13 49.1 3.4 2.1 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Phage_int_SAM_4 PF13495.6 KFP00318.1 - 0.12 12.9 0.2 20 5.7 0.0 2.6 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain BEN PF10523.9 KFP00319.1 - 1.3e-17 63.8 1.1 2.2e-17 63.1 0.1 2.0 2 0 0 2 2 2 1 BEN domain AIRS_C PF02769.22 KFP00321.1 - 6.8e-30 104.2 0.1 1e-29 103.7 0.1 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 KFP00321.1 - 9.1e-11 42.3 0.2 2.5e-10 40.9 0.2 1.7 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain PhyH PF05721.13 KFP00322.1 - 3.3e-44 151.7 0.0 4.1e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Mcm10 PF09332.11 KFP00323.1 - 6e-149 496.3 10.2 6e-149 496.3 10.2 3.0 3 1 1 4 4 4 1 Mcm10 replication factor zf-primase PF09329.11 KFP00323.1 - 8.8e-18 63.8 2.0 2.5e-17 62.4 2.0 1.9 1 0 0 1 1 1 1 Primase zinc finger NEMO PF11577.8 KFP00324.1 - 1.1e-30 105.4 14.4 1.1e-30 105.4 14.4 6.1 5 1 1 6 6 6 1 NF-kappa-B essential modulator NEMO CC2-LZ PF16516.5 KFP00324.1 - 7.2e-30 103.3 15.4 7.2e-30 103.3 15.4 5.5 3 2 1 5 5 5 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator zf_C2H2_10 PF18414.1 KFP00324.1 - 5e-16 57.9 6.5 1.1e-15 56.8 6.5 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger MLD PF11647.8 KFP00324.1 - 0.021 15.1 5.6 3.8 7.9 0.0 3.8 2 1 1 3 3 3 0 Membrane Localization Domain FGAR-AT_N PF18076.1 KFP00324.1 - 6.7 6.7 10.4 1.6 8.8 1.5 3.2 2 1 1 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase N-terminal YscO PF07321.12 KFP00325.1 - 9.1e-07 28.9 9.6 1.3e-06 28.4 9.6 1.2 1 0 0 1 1 1 1 Type III secretion protein YscO DUF812 PF05667.11 KFP00325.1 - 0.00017 20.6 4.3 0.00022 20.2 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) ATG16 PF08614.11 KFP00325.1 - 0.00019 21.7 6.0 0.00022 21.5 6.0 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 KFP00325.1 - 0.0005 20.1 3.9 0.0005 20.1 3.9 1.8 1 1 1 2 2 2 1 bZIP transcription factor KLRAQ PF10205.9 KFP00325.1 - 0.00086 19.5 8.1 0.0012 19.0 8.1 1.2 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein Fib_alpha PF08702.10 KFP00325.1 - 0.0013 19.0 2.7 0.0018 18.4 2.7 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.7 KFP00325.1 - 0.0016 18.6 7.8 0.002 18.3 7.8 1.1 1 0 0 1 1 1 1 Tropomyosin like DUF3450 PF11932.8 KFP00325.1 - 0.0023 17.3 3.7 0.0026 17.1 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF489 PF04356.12 KFP00325.1 - 0.0028 17.7 1.5 0.0035 17.4 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF489) DUF1664 PF07889.12 KFP00325.1 - 0.0057 16.7 3.5 0.008 16.2 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) TMCO5 PF14992.6 KFP00325.1 - 0.0064 16.1 4.2 0.0081 15.8 4.2 1.1 1 0 0 1 1 1 1 TMCO5 family Ax_dynein_light PF10211.9 KFP00325.1 - 0.0065 16.4 9.0 0.0085 16.1 9.0 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain Snapin_Pallidin PF14712.6 KFP00325.1 - 0.0066 16.8 4.3 0.012 16.0 4.3 1.5 1 0 0 1 1 1 1 Snapin/Pallidin Uso1_p115_C PF04871.13 KFP00325.1 - 0.013 15.9 5.2 0.019 15.4 5.2 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region FlaC_arch PF05377.11 KFP00325.1 - 0.014 15.7 1.6 0.036 14.4 1.6 1.8 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DegS PF05384.11 KFP00325.1 - 0.021 14.3 5.4 0.032 13.7 5.4 1.3 1 0 0 1 1 1 0 Sensor protein DegS Herpes_UL6 PF01763.16 KFP00325.1 - 0.021 13.4 2.7 0.022 13.3 2.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Atg14 PF10186.9 KFP00325.1 - 0.022 13.9 5.9 0.025 13.7 5.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prominin PF05478.11 KFP00325.1 - 0.024 12.6 1.1 0.024 12.6 1.1 1.1 1 0 0 1 1 1 0 Prominin UPF0242 PF06785.11 KFP00325.1 - 0.028 14.5 3.6 0.036 14.2 3.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMF_DNA_bd PF12329.8 KFP00325.1 - 0.029 14.4 9.7 0.048 13.7 9.7 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 KFP00325.1 - 0.036 14.5 8.8 0.063 13.7 8.8 1.4 1 0 0 1 1 1 0 Cell division protein ZapB P4Ha_N PF08336.11 KFP00325.1 - 0.037 14.0 3.3 0.06 13.4 3.3 1.3 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region BLOC1_2 PF10046.9 KFP00325.1 - 0.039 14.3 4.2 0.11 12.8 4.3 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EMP24_GP25L PF01105.24 KFP00325.1 - 0.044 13.7 3.5 0.058 13.3 3.5 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF4988 PF16378.5 KFP00325.1 - 0.047 13.4 1.0 0.069 12.8 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function Occludin_ELL PF07303.13 KFP00325.1 - 0.051 14.3 6.4 0.081 13.7 6.4 1.3 1 0 0 1 1 1 0 Occludin homology domain NPV_P10 PF05531.12 KFP00325.1 - 0.053 14.0 2.2 0.87 10.1 2.0 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TMPIT PF07851.13 KFP00325.1 - 0.058 12.6 3.1 0.064 12.5 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein LMBR1 PF04791.16 KFP00325.1 - 0.06 12.2 0.4 0.057 12.3 0.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SlyX PF04102.12 KFP00325.1 - 0.07 13.8 5.4 0.19 12.4 5.3 1.8 1 1 0 1 1 1 0 SlyX DivIC PF04977.15 KFP00325.1 - 0.075 12.8 8.2 0.14 12.0 8.1 1.5 1 1 0 1 1 1 0 Septum formation initiator GrpE PF01025.19 KFP00325.1 - 0.089 12.4 6.9 0.13 12.0 6.9 1.2 1 0 0 1 1 1 0 GrpE PRKCSH-like PF12999.7 KFP00325.1 - 0.12 12.2 2.0 0.15 11.8 2.0 1.2 1 0 0 1 1 1 0 Glucosidase II beta subunit-like ADIP PF11559.8 KFP00325.1 - 0.14 12.2 11.8 0.2 11.7 11.8 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Rotamase PF00639.21 KFP00325.1 - 0.14 13.1 1.4 0.22 12.5 1.1 1.6 1 1 0 1 1 1 0 PPIC-type PPIASE domain DUF773 PF05600.12 KFP00325.1 - 0.17 10.6 9.0 0.21 10.3 9.0 1.1 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 YabA PF06156.13 KFP00325.1 - 0.17 12.6 5.7 0.29 11.8 5.7 1.4 1 0 0 1 1 1 0 Initiation control protein YabA FapA PF03961.13 KFP00325.1 - 0.24 10.0 3.3 0.26 9.8 3.3 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 KFP00325.1 - 0.25 10.9 5.8 0.28 10.7 5.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit GIT_CC PF16559.5 KFP00325.1 - 0.4 10.6 9.4 0.8 9.6 1.3 2.4 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor XhlA PF10779.9 KFP00325.1 - 0.54 10.5 4.4 1 9.6 4.1 1.5 1 1 0 1 1 1 0 Haemolysin XhlA DUF4726 PF15855.5 KFP00325.1 - 0.6 10.4 2.4 1 9.6 2.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4726) DUF4446 PF14584.6 KFP00325.1 - 1.5 8.8 5.6 3 7.8 5.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) betaPIX_CC PF16523.5 KFP00325.1 - 2.3 8.1 11.0 5.7 6.8 11.0 1.6 1 1 0 1 1 1 0 betaPIX coiled coil Pkinase PF00069.25 KFP00327.1 - 1.2e-77 260.9 0.0 1.4e-77 260.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP00327.1 - 1.3e-35 123.0 0.0 1.6e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP00327.1 - 5.9e-09 35.6 0.0 7.4e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP00327.1 - 7.6e-05 21.7 0.0 0.00015 20.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFP00327.1 - 0.00011 21.7 0.1 0.00021 20.7 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFP00327.1 - 0.001 18.7 0.1 0.001 18.7 0.1 1.5 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KFP00327.1 - 0.0013 18.7 0.0 0.17 11.8 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family 5_nucleotid PF05761.14 KFP00327.1 - 0.035 13.0 0.1 0.056 12.4 0.1 1.2 1 0 0 1 1 1 0 5' nucleotidase family Pox_ser-thr_kin PF05445.11 KFP00327.1 - 0.078 11.9 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase D123 PF07065.14 KFP00328.1 - 2.3e-94 316.0 0.8 2.6e-94 315.8 0.8 1.0 1 0 0 1 1 1 1 D123 R2K_2 PF18299.1 KFP00328.1 - 0.032 14.1 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 ATPgrasp_YheCD PF14398.6 KFP00328.1 - 0.13 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 YheC/D like ATP-grasp NUDIX PF00293.28 KFP00329.1 - 6.7e-16 58.5 0.5 2.7e-15 56.6 0.1 1.9 2 0 0 2 2 2 1 NUDIX domain DUF3833 PF12915.7 KFP00329.1 - 0.14 11.7 0.2 0.24 11.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3833) SecY PF00344.20 KFP00330.1 - 2.1e-74 250.5 13.9 2.8e-74 250.1 13.9 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KFP00330.1 - 8e-19 67.2 0.2 2.5e-18 65.6 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p DUF2975 PF11188.8 KFP00330.1 - 5.8 6.8 12.8 0.5 10.3 3.6 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF2975) Transket_pyr PF02779.24 KFP00331.1 - 8.1e-63 211.3 0.0 1.4e-62 210.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 KFP00331.1 - 2.2e-45 154.0 0.0 3.4e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 KFP00331.1 - 2.1e-44 151.7 0.0 4.8e-44 150.5 0.0 1.5 1 1 0 1 1 1 1 Dehydrogenase E1 component MIF4G PF02854.19 KFP00333.1 - 4.9e-42 144.0 0.0 8.7e-42 143.1 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain Upf2 PF04050.14 KFP00333.1 - 2.1e-17 64.1 0.4 2.1e-17 64.1 0.4 2.6 1 1 1 2 2 2 1 Up-frameshift suppressor 2 CobT PF06213.12 KFP00333.1 - 0.26 10.7 17.9 0.39 10.1 17.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.12 KFP00333.1 - 0.68 8.1 25.2 0.88 7.7 25.2 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KFP00333.1 - 1.4 8.2 22.5 1.9 7.8 22.5 1.1 1 0 0 1 1 1 0 SDA1 DUF913 PF06025.12 KFP00333.1 - 1.7 7.6 4.2 2.3 7.1 4.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BUD22 PF09073.10 KFP00333.1 - 3.1 7.0 18.2 4.1 6.6 18.2 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 KFP00333.1 - 3.5 5.8 13.8 4.6 5.4 13.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KFP00333.1 - 7.5 5.2 9.0 11 4.6 9.0 1.2 1 0 0 1 1 1 0 Presenilin SARG PF15385.6 KFP00334.1 - 7e-15 55.3 38.1 2.4e-09 37.0 1.3 4.0 1 1 2 3 3 3 2 Specifically androgen-regulated gene protein ECH_1 PF00378.20 KFP00335.1 - 5.9e-53 179.7 0.0 6.5e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFP00335.1 - 3.5e-33 115.5 0.0 3.6e-30 105.6 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase RRM_1 PF00076.22 KFP00337.1 - 9.4e-52 172.7 0.0 6.4e-18 64.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 KFP00337.1 - 2.1e-10 40.5 0.0 0.089 12.8 0.0 4.0 3 1 0 3 3 3 3 RNA binding domain RRM_7 PF16367.5 KFP00337.1 - 6e-05 23.1 0.1 0.35 11.0 0.0 3.5 3 1 0 3 3 3 2 RNA recognition motif PHM7_cyt PF14703.6 KFP00337.1 - 0.00087 19.6 3.0 0.71 10.1 0.1 4.2 3 1 1 4 4 4 2 Cytosolic domain of 10TM putative phosphate transporter GATA PF00320.27 KFP00339.1 - 2e-29 100.9 19.4 1.1e-14 53.7 5.2 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KFP00339.1 - 1.8e-05 24.1 7.9 0.023 14.2 0.7 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding DUF2387 PF09526.10 KFP00339.1 - 0.014 15.5 5.4 2.7 8.2 0.6 3.3 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) Zn-ribbon_8 PF09723.10 KFP00339.1 - 0.019 15.0 2.6 2.6 8.2 0.1 2.8 2 1 0 2 2 2 0 Zinc ribbon domain ArfGap PF01412.18 KFP00339.1 - 0.046 13.8 8.4 0.1 12.7 0.4 2.7 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf Auto_anti-p27 PF06677.12 KFP00339.1 - 0.083 13.1 5.2 1.2 9.4 0.4 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Prim_Zn_Ribbon PF08273.12 KFP00339.1 - 0.43 10.9 9.4 0.37 11.1 2.1 2.8 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DZR PF12773.7 KFP00339.1 - 1.7 8.7 12.8 6.5 6.9 2.4 3.1 1 1 1 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 KFP00339.1 - 6.9 6.7 13.0 7.5 6.6 2.7 3.1 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Elf1 PF05129.13 KFP00339.1 - 7.1 6.8 8.3 11 6.1 0.3 2.8 2 1 1 3 3 2 0 Transcription elongation factor Elf1 like eIF-5_eIF-2B PF01873.17 KFP00339.1 - 8.7 6.3 9.1 15 5.4 1.2 2.7 3 0 0 3 3 3 0 Domain found in IF2B/IF5 Vps36-NZF-N PF16988.5 KFP00339.1 - 9.4 5.7 8.7 1.3 8.5 0.4 3.0 2 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Bromo_TP PF07524.13 KFP00340.1 - 3.2e-16 59.1 0.0 4.8e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated PHD PF00628.29 KFP00340.1 - 1.2e-10 41.1 7.1 3.4e-10 39.7 7.1 1.8 1 0 0 1 1 1 1 PHD-finger RNA_pol_Rpc4 PF05132.14 KFP00340.1 - 0.008 16.6 13.6 0.008 16.6 13.6 5.9 5 1 1 6 6 6 1 RNA polymerase III RPC4 PHD_2 PF13831.6 KFP00340.1 - 0.011 15.3 1.5 0.011 15.3 1.5 2.1 2 0 0 2 2 2 0 PHD-finger ATP-synt PF00231.19 KFP00341.1 - 1.9e-80 270.6 2.5 2.1e-80 270.4 2.5 1.0 1 0 0 1 1 1 1 ATP synthase Kin17_mid PF10357.9 KFP00342.1 - 1.4e-50 170.4 3.2 1.4e-50 170.4 3.2 2.0 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 KFP00342.1 - 1.4e-22 79.6 7.6 1.7e-22 79.3 6.4 1.8 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain KOW PF00467.29 KFP00342.1 - 0.00043 20.1 4.0 0.00066 19.5 0.0 3.1 2 1 1 3 3 3 1 KOW motif SecM PF06558.12 KFP00342.1 - 0.0041 17.2 0.0 0.0075 16.4 0.0 1.5 1 0 0 1 1 1 1 Secretion monitor precursor protein (SecM) zf-met PF12874.7 KFP00342.1 - 0.058 13.8 9.0 0.13 12.7 9.0 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Caskin-tail PF16632.5 KFP00342.1 - 0.062 13.7 0.4 0.24 11.8 0.4 2.0 1 0 0 1 1 1 0 C-terminal region of Caskin zf-C2H2_jaz PF12171.8 KFP00342.1 - 0.35 11.2 8.5 0.78 10.1 8.5 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFP00342.1 - 4 7.8 9.9 0.14 12.5 2.6 2.3 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) ITI_HC_C PF06668.12 KFP00343.1 - 4.7e-73 244.9 0.3 9.4e-73 243.9 0.3 1.5 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus VWA PF00092.28 KFP00343.1 - 5.4e-21 75.6 0.2 1e-20 74.7 0.2 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFP00343.1 - 5e-18 65.5 0.0 8e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFP00343.1 - 1.8e-12 47.9 0.1 6.6e-12 46.0 0.1 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 KFP00343.1 - 2.3e-09 37.5 0.1 5.7e-09 36.2 0.1 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.14 KFP00343.1 - 0.00017 21.0 0.0 0.00032 20.1 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein SWIB PF02201.18 KFP00343.1 - 0.048 13.6 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 SWIB/MDM2 domain STIMATE PF12400.8 KFP00344.1 - 3.7e-33 114.7 10.4 5.4e-33 114.2 10.4 1.2 1 0 0 1 1 1 1 STIMATE family TMEM154 PF15102.6 KFP00344.1 - 0.09 12.7 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family Vpu PF00558.19 KFP00344.1 - 0.2 11.4 3.0 0.26 11.1 0.0 2.4 2 0 0 2 2 2 0 Vpu protein MBT PF02820.18 KFP00345.1 - 2.6e-78 258.3 5.2 2.2e-22 79.2 0.1 4.7 5 0 0 5 5 5 4 mbt repeat SLED PF12140.8 KFP00345.1 - 7.4e-39 132.7 0.1 1.5e-38 131.8 0.1 1.5 1 0 0 1 1 1 1 SLED domain SAM_1 PF00536.30 KFP00345.1 - 0.00016 22.1 0.0 0.00032 21.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFP00345.1 - 0.00025 20.9 0.0 0.00065 19.6 0.0 1.7 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.17 KFP00345.1 - 0.037 14.1 0.0 0.083 13.0 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) 6PF2K PF01591.18 KFP00346.1 - 6.4e-105 349.4 0.0 1.1e-104 348.6 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KFP00346.1 - 1.6e-42 145.4 0.0 2.2e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KFP00346.1 - 7.2e-07 29.5 0.0 1.7e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KFP00346.1 - 0.002 17.6 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 KFP00346.1 - 0.013 14.8 0.0 0.032 13.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin His_Phos_2 PF00328.22 KFP00346.1 - 0.045 13.1 0.0 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) AAA_17 PF13207.6 KFP00346.1 - 0.19 12.1 0.0 0.4 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain G-patch PF01585.23 KFP00347.1 - 3.4e-13 49.3 1.5 7.6e-13 48.1 1.5 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KFP00347.1 - 5.2e-05 23.0 0.1 0.0001 22.0 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nucleo_P87 PF07267.11 KFP00347.1 - 2.7 6.7 5.4 3.6 6.3 5.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.14 KFP00347.1 - 6.1 5.0 6.1 9.2 4.4 6.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Sushi PF00084.20 KFP00348.1 - 2.1e-08 34.6 1.1 2.7e-08 34.3 1.1 1.2 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) Endonuclease_NS PF01223.23 KFP00349.1 - 1.9e-26 93.3 0.8 3.1e-26 92.6 0.8 1.3 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 KFP00349.1 - 0.0015 18.7 0.5 0.0029 17.7 0.0 1.6 2 0 0 2 2 2 1 DNA/RNA non-specific endonuclease Muskelin_N PF06588.11 KFP00351.1 - 4.6e-90 300.8 0.5 7.3e-90 300.2 0.5 1.3 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_3 PF13415.6 KFP00351.1 - 2.8e-21 75.3 4.8 2.8e-10 40.2 0.0 5.1 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KFP00351.1 - 2.4e-18 65.4 17.1 1.5e-06 27.7 0.3 6.1 6 1 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 KFP00351.1 - 4.6e-16 58.5 5.4 0.0054 17.0 0.1 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 KFP00351.1 - 3.5e-15 55.7 9.2 5.9e-05 23.0 0.1 6.1 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP00351.1 - 1.4e-14 53.7 12.0 0.00032 20.6 0.2 6.6 6 1 0 6 6 6 4 Kelch motif F5_F8_type_C PF00754.25 KFP00351.1 - 2e-07 31.2 0.0 4.6e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain Kelch_2 PF07646.15 KFP00351.1 - 1.5e-05 24.8 12.3 0.11 12.6 0.1 6.1 6 1 1 7 7 7 2 Kelch motif Sad1_UNC PF07738.13 KFP00351.1 - 0.029 14.4 0.0 0.074 13.1 0.0 1.6 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal CD34_antigen PF06365.12 KFP00352.1 - 5.7e-48 163.3 0.5 6.3e-48 163.1 0.5 1.0 1 0 0 1 1 1 1 CD34/Podocalyxin family Plexin_cytopl PF08337.12 KFP00353.1 - 6.7e-253 840.4 0.4 8.2e-253 840.1 0.4 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.24 KFP00353.1 - 1e-43 147.3 5.0 1.4e-13 50.7 0.1 6.7 7 0 0 7 7 7 4 IPT/TIG domain TIG_2 PF18020.1 KFP00353.1 - 7.8e-35 119.4 0.5 3.9e-34 117.1 0.1 2.5 2 0 0 2 2 2 1 TIG domain found in plexin PSI PF01437.25 KFP00353.1 - 7e-23 80.9 56.5 2.2e-10 40.9 14.8 3.6 3 0 0 3 3 3 3 Plexin repeat TIG_plexin PF17960.1 KFP00353.1 - 6.5e-22 77.3 10.6 1.3e-20 73.2 0.1 5.1 6 0 0 6 6 6 2 TIG domain PSI_integrin PF17205.3 KFP00353.1 - 0.00089 19.0 49.1 0.0015 18.2 13.2 3.6 3 0 0 3 3 3 3 Integrin plexin domain RasGAP PF00616.19 KFP00353.1 - 0.0024 17.6 0.9 0.46 10.2 0.9 2.7 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase Sema PF01403.19 KFP00354.1 - 5e-62 210.1 0.0 6.1e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 Sema domain DUF737 PF05300.11 KFP00355.1 - 2.1e-35 123.0 24.6 2.8e-35 122.5 24.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF737) CHCH PF06747.13 KFP00355.1 - 0.0006 19.9 1.2 0.0012 18.9 1.2 1.5 1 0 0 1 1 1 1 CHCH domain Exonuc_VII_L PF02601.15 KFP00355.1 - 0.36 10.3 11.9 0.43 10.1 11.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Jnk-SapK_ap_N PF09744.9 KFP00355.1 - 0.45 10.7 20.4 0.67 10.2 19.9 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 ECH_2 PF16113.5 KFP00355.1 - 0.63 9.5 4.1 0.71 9.3 4.1 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase ZnuA PF01297.17 KFP00355.1 - 0.73 9.2 3.1 1.4 8.3 3.1 1.5 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Spc24 PF08286.11 KFP00355.1 - 3.3 8.0 9.6 0.35 11.1 2.1 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF2570 PF10828.8 KFP00355.1 - 3.5 7.5 8.7 0.37 10.6 3.0 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2570) KxDL PF10241.9 KFP00355.1 - 3.9 7.8 11.2 0.91 9.8 4.2 2.9 3 1 0 3 3 3 0 Uncharacterized conserved protein Guanylate_kin PF00625.21 KFP00358.1 - 6.2e-28 97.7 0.0 1.2e-27 96.8 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase LRR_4 PF12799.7 KFP00358.1 - 2.3e-18 66.0 36.7 5e-06 26.8 3.1 5.4 3 2 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP00358.1 - 2.3e-14 52.9 33.7 0.0001 22.0 4.4 5.1 2 1 3 5 5 5 5 Leucine rich repeat LRR_6 PF13516.6 KFP00358.1 - 3e-08 33.1 26.4 0.012 15.6 0.9 7.1 7 0 0 7 7 7 5 Leucine Rich repeat LRR_9 PF14580.6 KFP00358.1 - 0.00016 21.2 11.2 0.048 13.2 3.1 3.1 2 1 1 3 3 3 2 Leucine-rich repeat Arm_3 PF16186.5 KFP00358.1 - 0.061 12.9 0.8 1 9.0 0.0 3.1 3 0 0 3 3 3 0 Atypical Arm repeat LRR_1 PF00560.33 KFP00358.1 - 0.54 11.0 26.9 8.1 7.4 0.7 7.5 6 2 0 6 6 6 0 Leucine Rich Repeat UAA PF08449.11 KFP00359.1 - 3.5e-108 361.4 21.1 3.9e-108 361.2 21.1 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 KFP00359.1 - 5.2e-05 22.7 16.1 0.00092 18.6 16.1 2.0 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFP00359.1 - 0.023 14.9 29.5 0.02 15.1 14.4 2.8 2 1 0 2 2 2 0 EamA-like transporter family Collagen PF01391.18 KFP00360.1 - 6.9e-88 288.4 397.8 1.3e-08 34.4 29.7 17.1 5 3 9 14 14 14 13 Collagen triple helix repeat (20 copies) VWA PF00092.28 KFP00360.1 - 5.3e-42 144.0 0.0 1.7e-38 132.6 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain fn3 PF00041.21 KFP00360.1 - 1.5e-36 124.6 2.1 1.6e-12 47.6 0.0 5.4 5 0 0 5 5 5 5 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFP00360.1 - 1.1e-08 35.5 0.4 0.44 11.1 0.7 4.5 4 0 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain VWA_2 PF13519.6 KFP00360.1 - 1.8e-07 31.8 0.0 2.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4992 PF16383.5 KFP00360.1 - 0.0038 16.8 0.0 22 4.5 0.0 3.9 4 0 0 4 4 4 2 Domain of unknown function CRF PF00473.17 KFP00362.1 - 2.8e-14 52.9 5.1 9.1e-14 51.2 1.3 2.4 2 0 0 2 2 2 1 Corticotropin-releasing factor family DUF1687 PF07955.11 KFP00362.1 - 0.006 17.1 0.3 0.0082 16.6 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Tad_C PF09977.9 KFP00362.1 - 0.059 14.6 0.0 0.079 14.2 0.0 1.4 1 1 0 1 1 1 0 Putative Tad-like Flp pilus-assembly ExbD PF02472.16 KFP00362.1 - 0.29 11.3 3.3 2.6 8.2 3.3 2.1 1 1 0 1 1 1 0 Biopolymer transport protein ExbD/TolR Tubulin PF00091.25 KFP00363.1 - 1e-48 166.2 0.0 1.6e-48 165.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFP00363.1 - 8.7e-44 148.7 0.0 1.3e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain RhoGEF PF00621.20 KFP00364.1 - 3e-25 89.5 0.0 7e-22 78.5 0.0 2.4 1 1 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 KFP00364.1 - 2.8e-08 33.7 0.3 1.9e-07 31.0 0.1 2.4 2 1 0 2 2 2 1 Pleckstrin homology domain PH_5 PF15405.6 KFP00364.1 - 1.4e-07 31.7 0.2 8.8e-07 29.1 0.2 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFP00364.1 - 2.8e-07 31.0 0.0 5.4e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 KFP00364.1 - 0.011 15.7 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 PH domain EF-hand_1 PF00036.32 KFP00365.1 - 2e-40 133.3 5.8 4.7e-10 38.3 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFP00365.1 - 4.4e-35 120.0 0.7 2.7e-18 66.2 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFP00365.1 - 1.2e-31 108.3 8.4 3.1e-14 52.6 0.3 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KFP00365.1 - 1.5e-31 105.6 3.9 1.9e-09 36.7 0.0 4.5 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 KFP00365.1 - 1.2e-22 78.3 7.5 1.2e-06 27.7 0.0 4.7 5 0 0 5 5 5 4 EF hand EF-hand_9 PF14658.6 KFP00365.1 - 1.5e-15 57.2 0.0 3.5e-08 33.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KFP00365.1 - 5e-08 32.8 0.1 0.0027 17.6 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFP00365.1 - 5.4e-07 29.9 0.0 0.00041 20.6 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.10 KFP00365.1 - 8.1e-06 25.8 0.2 2e-05 24.6 0.2 1.7 1 0 0 1 1 1 1 Ca2+ insensitive EF hand UPF0154 PF03672.13 KFP00365.1 - 1.1e-05 25.4 0.0 0.21 11.7 0.0 3.0 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 KFP00365.1 - 4.5e-05 24.3 0.0 0.02 15.8 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain Caleosin PF05042.13 KFP00365.1 - 0.0002 21.3 0.2 0.21 11.5 0.0 3.1 1 1 1 3 3 3 1 Caleosin related protein Dockerin_1 PF00404.18 KFP00365.1 - 0.00022 21.4 0.4 0.26 11.5 0.1 3.0 1 1 3 4 4 4 2 Dockerin type I domain RNA_pol_Rpb4 PF03874.16 KFP00365.1 - 0.0004 20.7 0.5 0.38 11.1 0.1 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb4 DUF3349 PF11829.8 KFP00365.1 - 0.0015 19.3 0.0 7.3 7.5 0.1 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Poly_export PF02563.16 KFP00365.1 - 0.0055 16.9 0.1 0.26 11.5 0.0 2.6 1 1 2 3 3 3 1 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 KFP00365.1 - 0.0057 17.1 0.0 0.88 10.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4497) DUF5580 PF17743.1 KFP00365.1 - 0.0074 14.9 0.0 0.0079 14.8 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) TerB PF05099.13 KFP00365.1 - 0.012 15.5 0.2 2.7 7.9 0.1 2.2 1 1 1 2 2 2 0 Tellurite resistance protein TerB SapB_1 PF05184.15 KFP00365.1 - 0.013 15.5 0.5 10 6.3 0.3 3.2 3 0 0 3 3 3 0 Saposin-like type B, region 1 Fe_hyd_lg_C PF02906.14 KFP00365.1 - 0.037 13.7 0.4 0.15 11.7 0.4 1.9 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Ank_2 PF12796.7 KFP00366.1 - 4.6e-50 168.1 11.3 5.3e-17 62.2 2.8 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP00366.1 - 1.9e-42 143.1 9.1 9.2e-11 42.1 1.1 4.4 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KFP00366.1 - 1.3e-39 132.9 10.6 9e-07 29.1 0.1 6.6 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 KFP00366.1 - 7.8e-31 102.7 3.6 0.00014 22.0 0.0 6.5 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 KFP00366.1 - 1.8e-26 91.8 6.0 1.3e-06 28.6 0.1 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFP00366.1 - 4.7e-10 39.7 1.2 8.1e-10 38.9 1.2 1.4 1 0 0 1 1 1 1 SOCS box Prok-RING_1 PF14446.6 KFP00366.1 - 4.9 7.2 6.0 13 5.8 0.3 3.3 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 DUF5528 PF17666.1 KFP00367.1 - 0.11 12.4 0.3 0.14 12.1 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5528) DUF3715 PF12509.8 KFP00368.1 - 0.00094 19.2 0.1 0.0017 18.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3715) GDI PF00996.18 KFP00369.1 - 1.8e-226 751.7 0.1 2.2e-226 751.4 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor SH3_14 PF18343.1 KFP00369.1 - 0.033 14.3 2.6 3.4 7.8 0.3 3.2 2 1 0 3 3 3 0 Dda helicase SH3 domain Amino_oxidase PF01593.24 KFP00369.1 - 0.057 12.7 0.0 0.076 12.3 0.0 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase EGF PF00008.27 KFP00371.1 - 8.2e-38 128.3 137.6 1.1e-08 35.2 6.0 9.9 9 1 0 9 9 9 6 EGF-like domain hEGF PF12661.7 KFP00371.1 - 1.4e-28 98.5 112.3 9.7e-07 29.2 10.6 10.4 11 0 0 11 11 11 6 Human growth factor-like EGF DSL PF01414.19 KFP00371.1 - 1e-23 83.3 8.3 1e-23 83.3 8.3 6.6 4 3 2 6 6 6 2 Delta serrate ligand EGF_CA PF07645.15 KFP00371.1 - 8.4e-06 25.9 27.0 5e-05 23.4 9.5 9.6 5 2 3 9 9 9 5 Calcium-binding EGF domain EGF_3 PF12947.7 KFP00371.1 - 6.1e-05 23.1 21.4 0.00034 20.7 9.1 10.2 8 3 2 10 10 10 4 EGF domain EGF_2 PF07974.13 KFP00371.1 - 0.0056 17.0 11.5 0.0056 17.0 11.5 11.3 10 1 0 10 10 10 5 EGF-like domain ECSCR PF15820.5 KFP00371.1 - 0.029 14.2 0.1 0.071 12.9 0.1 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator FXa_inhibition PF14670.6 KFP00371.1 - 4.2 7.7 115.7 0.092 13.0 10.9 10.1 2 1 6 8 8 8 0 Coagulation Factor Xa inhibitory site DUF4209 PF13910.6 KFP00372.1 - 7.7e-28 96.6 0.1 2.9e-23 81.9 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4209) Tctex-1 PF03645.13 KFP00373.1 - 2.2e-21 76.0 0.9 2.7e-21 75.7 0.9 1.1 1 0 0 1 1 1 1 Tctex-1 family CDO_I PF05995.12 KFP00373.1 - 0.057 12.7 0.1 0.066 12.5 0.1 1.1 1 0 0 1 1 1 0 Cysteine dioxygenase type I PHD PF00628.29 KFP00374.1 - 3.8e-17 61.9 25.0 8.2e-09 35.2 10.6 2.4 1 1 1 2 2 2 2 PHD-finger PHD_4 PF16866.5 KFP00374.1 - 0.0023 18.0 9.7 0.0023 18.0 9.7 3.4 2 1 1 3 3 3 1 PHD-finger PHD_2 PF13831.6 KFP00374.1 - 0.016 14.8 5.1 0.016 14.8 5.1 2.7 2 1 0 2 2 2 0 PHD-finger Herpes_MCP PF03122.14 KFP00374.1 - 0.035 11.6 0.2 0.047 11.1 0.2 1.0 1 0 0 1 1 1 0 Herpes virus major capsid protein zf-PHD-like PF15446.6 KFP00374.1 - 2.9 7.5 17.5 0.92 9.1 2.7 3.0 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 KFP00374.1 - 9.3 6.2 26.1 0.54 10.2 0.8 3.0 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) UPF0669 PF17065.5 KFP00375.1 - 9.3e-107 354.7 0.2 1e-106 354.6 0.2 1.0 1 0 0 1 1 1 1 Putative cytokine, C6ORF120 TPR_2 PF07719.17 KFP00376.1 - 4.2e-05 23.3 0.0 0.027 14.6 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFP00376.1 - 0.0012 18.5 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.28 KFP00376.1 - 0.0053 16.5 0.0 1.4 8.9 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP00376.1 - 0.067 13.4 0.0 13 6.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFP00376.1 - 0.097 13.0 0.0 0.19 12.0 0.0 1.5 1 1 0 1 1 1 0 Tetratricopeptide repeat UvrD-helicase PF00580.21 KFP00377.1 - 3.4e-08 33.4 0.3 3.4e-08 33.4 0.3 4.1 4 2 0 4 4 4 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KFP00377.1 - 3.8e-07 29.8 0.0 0.00082 18.9 0.0 5.1 4 2 1 5 5 5 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 KFP00377.1 - 2.3e-06 27.3 0.0 0.093 12.6 0.0 2.6 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Clathrin PF00637.20 KFP00377.1 - 9.3e-06 25.6 12.6 0.012 15.5 0.2 4.1 3 1 1 4 4 4 2 Region in Clathrin and VPS AAA_19 PF13245.6 KFP00377.1 - 0.0021 18.4 0.6 0.88 9.9 0.0 3.6 4 0 0 4 4 4 1 AAA domain ABC_tran PF00005.27 KFP00377.1 - 0.078 13.5 0.5 0.34 11.4 0.0 2.5 2 0 0 2 2 2 0 ABC transporter Terminase_2 PF03592.16 KFP00377.1 - 0.78 10.2 4.3 4 7.9 4.3 2.2 1 0 0 1 1 1 0 Terminase small subunit Pkinase PF00069.25 KFP00378.1 - 6.4e-81 271.6 0.0 7.2e-81 271.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP00378.1 - 4.2e-37 127.8 0.0 5.1e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP00378.1 - 0.0014 18.0 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP00378.1 - 0.0028 16.5 0.0 0.0042 15.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFP00378.1 - 0.0036 16.7 0.0 0.0055 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KFP00378.1 - 0.014 14.9 0.5 0.044 13.3 0.1 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL APH PF01636.23 KFP00378.1 - 0.023 14.6 0.0 0.33 10.8 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family STAC2_u1 PF16664.5 KFP00379.1 - 1.4e-29 103.2 0.1 1.4e-29 103.2 0.1 2.8 2 1 1 3 3 2 1 Unstructured on SH3 and cysteine-rich domain-containing protein 2 SH3_9 PF14604.6 KFP00379.1 - 1.7e-19 69.4 0.0 1.3e-15 57.0 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KFP00379.1 - 8e-17 60.7 0.1 4.8e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KFP00379.1 - 1.3e-16 60.0 0.7 1e-14 53.9 0.1 2.4 2 0 0 2 2 2 1 SH3 domain C1_1 PF00130.22 KFP00379.1 - 2.5e-10 40.1 10.6 6.2e-10 38.8 10.6 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_9 PF13901.6 KFP00379.1 - 0.0011 19.0 2.4 0.0019 18.3 2.4 1.4 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon C1_2 PF03107.16 KFP00379.1 - 0.0081 16.4 3.4 0.0081 16.4 3.4 2.1 2 0 0 2 2 2 1 C1 domain RNA_POL_M_15KD PF02150.16 KFP00379.1 - 0.089 12.7 1.3 0.19 11.6 1.3 1.5 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit PHD PF00628.29 KFP00379.1 - 0.29 11.1 8.2 0.67 9.9 8.2 1.6 1 0 0 1 1 1 0 PHD-finger BssC_TutF PF08201.11 KFP00379.1 - 0.32 11.0 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 BssC/TutF protein Zf_RING PF16744.5 KFP00379.1 - 0.41 10.8 4.0 0.95 9.6 4.0 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger Ndc1_Nup PF09531.10 KFP00379.1 - 1.9 7.1 5.2 2.7 6.6 5.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-RING-like PF08746.11 KFP00379.1 - 2.3 8.6 10.2 5.7 7.3 10.2 1.7 1 0 0 1 1 1 0 RING-like domain R3H PF01424.22 KFP00380.1 - 3e-12 46.3 0.6 9e-12 44.8 0.1 2.1 2 0 0 2 2 2 1 R3H domain CLASP_N PF12348.8 KFP00381.1 - 1.2e-51 175.4 6.5 2.1e-36 125.6 0.1 4.3 4 0 0 4 4 4 3 CLASP N terminal HEAT PF02985.22 KFP00381.1 - 2e-14 52.5 13.7 0.0079 16.4 0.0 10.2 11 0 0 11 11 9 3 HEAT repeat HEAT_2 PF13646.6 KFP00381.1 - 3.1e-09 37.1 1.2 0.86 10.0 0.3 8.0 6 3 3 9 9 9 2 HEAT repeats Cnd1 PF12717.7 KFP00381.1 - 5.7e-08 33.0 11.3 0.0096 16.0 0.5 6.4 5 3 2 8 8 8 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KFP00381.1 - 1.6e-07 31.7 1.7 0.046 14.2 0.0 5.9 6 0 0 6 6 5 1 HEAT-like repeat RTP1_C1 PF10363.9 KFP00381.1 - 1.9e-07 31.2 3.4 0.021 15.0 0.1 3.9 3 1 1 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 KFP00381.1 - 4.9e-05 23.9 3.2 25 5.5 0.0 6.1 6 0 0 6 6 5 0 Vacuolar 14 Fab1-binding region Sec7_N PF12783.7 KFP00381.1 - 0.00011 22.1 6.2 3 7.7 1.3 4.8 5 0 0 5 5 5 2 Guanine nucleotide exchange factor in Golgi transport N-terminal ParcG PF10274.9 KFP00381.1 - 0.00025 21.2 2.2 0.0026 17.9 0.1 3.0 2 1 1 3 3 3 1 Parkin co-regulated protein Adaptin_N PF01602.20 KFP00381.1 - 0.00027 19.6 6.9 0.34 9.4 0.1 5.8 5 1 0 6 6 6 1 Adaptin N terminal region TFCD_C PF12612.8 KFP00381.1 - 0.00073 19.4 0.4 0.1 12.4 0.1 4.3 5 0 0 5 5 5 1 Tubulin folding cofactor D C terminal MMS19_N PF14500.6 KFP00381.1 - 0.00079 19.1 4.7 4.4 6.8 0.1 3.7 3 0 0 3 3 3 3 Dos2-interacting transcription regulator of RNA-Pol-II Ipi1_N PF12333.8 KFP00381.1 - 0.024 15.2 2.1 0.36 11.4 0.0 3.5 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation MMS19_C PF12460.8 KFP00381.1 - 0.031 13.4 7.2 1.1 8.3 0.1 3.3 4 0 0 4 4 4 0 RNAPII transcription regulator C-terminal TAN PF11640.8 KFP00381.1 - 0.1 12.7 5.7 0.13 12.4 0.1 3.8 3 1 1 4 4 3 0 Telomere-length maintenance and DNA damage repair Dopey_N PF04118.14 KFP00381.1 - 0.28 10.2 3.0 1.4 8.0 0.1 3.2 4 0 0 4 4 4 0 Dopey, N-terminal CP2 PF04516.15 KFP00382.1 - 1.7e-58 197.6 0.0 2.5e-58 197.1 0.0 1.1 1 0 0 1 1 1 1 CP2 transcription factor SAM_3 PF18016.1 KFP00382.1 - 2.4e-20 72.1 0.0 3.8e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP00382.1 - 0.0083 16.2 0.0 0.024 14.8 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFP00382.1 - 0.0089 16.0 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_1 PF00536.30 KFP00382.1 - 0.029 14.8 0.0 0.068 13.6 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) LRR_6 PF13516.6 KFP00383.1 - 1.6e-19 68.2 39.8 6.8e-05 22.6 0.1 10.6 12 0 0 12 12 12 5 Leucine Rich repeat LRR_4 PF12799.7 KFP00383.1 - 1.8e-14 53.6 25.3 0.028 14.8 1.6 7.2 4 1 2 8 8 8 7 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KFP00383.1 - 4.2e-13 49.0 0.6 1.8e-12 47.0 0.6 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFP00383.1 - 5.2e-08 32.6 2.2 1.2e-07 31.4 0.7 2.6 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 KFP00383.1 - 5.3e-06 26.2 34.7 0.23 12.1 0.1 10.5 10 1 0 10 10 10 2 Leucine Rich Repeat LRR_8 PF13855.6 KFP00383.1 - 0.0047 16.7 20.2 1.4 8.8 4.4 6.4 5 3 1 6 6 6 2 Leucine rich repeat F-box_4 PF15966.5 KFP00383.1 - 0.015 15.1 0.1 0.015 15.1 0.1 2.9 4 0 0 4 4 4 0 F-box Mating_N PF12731.7 KFP00383.1 - 0.051 13.7 0.1 1.7 8.8 0.1 2.6 1 1 0 2 2 2 0 Mating-type protein beta 1 PTE PF02126.18 KFP00383.1 - 0.12 11.7 0.0 14 5.0 0.0 2.5 2 1 0 2 2 2 0 Phosphotriesterase family Xlink PF00193.17 KFP00384.1 - 2e-15 56.9 0.2 6.4e-15 55.3 0.2 1.9 1 0 0 1 1 1 1 Extracellular link domain Sushi PF00084.20 KFP00384.1 - 1e-05 26.0 0.9 1e-05 26.0 0.9 2.3 2 0 0 2 2 2 1 Sushi repeat (SCR repeat) GAPT PF11770.8 KFP00384.1 - 0.004 17.0 0.2 0.0098 15.8 0.2 1.6 1 0 0 1 1 1 1 GRB2-binding adapter (GAPT) SIT PF15330.6 KFP00384.1 - 0.0047 17.4 0.2 0.018 15.5 0.2 2.0 1 0 0 1 1 1 1 SHP2-interacting transmembrane adaptor protein, SIT DUF4366 PF14283.6 KFP00384.1 - 0.018 15.1 1.0 0.087 12.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Insulin_TMD PF17870.1 KFP00384.1 - 0.03 14.4 0.4 0.064 13.3 0.4 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Ly49 PF08391.10 KFP00384.1 - 0.093 13.1 0.3 0.2 12.0 0.3 1.5 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region ERGIC_N PF13850.6 KFP00384.1 - 0.11 12.8 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) EphA2_TM PF14575.6 KFP00384.1 - 0.19 12.6 0.3 0.19 12.6 0.3 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Whi5 PF08528.11 KFP00385.1 - 0.26 11.0 8.2 2.5 7.8 0.7 2.7 2 0 0 2 2 2 0 Whi5 like TPR_2 PF07719.17 KFP00385.1 - 0.42 10.9 4.9 27 5.2 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Metallophos PF00149.28 KFP00386.1 - 1.3e-13 51.9 0.1 1.8e-13 51.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFP00386.1 - 2.9e-05 24.3 0.0 6.4e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_35 PF01301.19 KFP00387.1 - 7.7e-103 344.4 0.1 3.4e-102 342.3 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 KFP00387.1 - 3.1e-13 49.8 0.0 1.1e-08 34.9 0.0 2.2 1 1 1 2 2 2 2 Beta-galactosidase BetaGal_dom4_5 PF13364.6 KFP00387.1 - 3e-07 31.0 0.7 2.6e-06 28.0 0.0 2.6 3 1 1 4 4 4 1 Beta-galactosidase jelly roll domain 7tm_1 PF00001.21 KFP00388.1 - 4.5e-54 183.5 23.9 6.1e-54 183.1 23.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP00388.1 - 1.2e-09 37.9 25.9 1.8e-09 37.3 25.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 KFP00388.1 - 2.3e-05 23.8 21.5 0.011 15.0 21.5 2.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 KFP00390.1 - 1.3e-53 182.0 21.0 1.6e-53 181.7 21.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP00390.1 - 4e-09 36.2 20.6 5.7e-09 35.7 20.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx UL2 PF08196.11 KFP00390.1 - 0.61 10.1 0.0 0.61 10.1 0.0 2.5 3 0 0 3 3 3 0 UL2 protein Mito_carr PF00153.27 KFP00391.1 - 1.9e-59 197.6 8.5 1.6e-20 72.8 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein TRAPP PF04051.16 KFP00391.1 - 0.044 13.5 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Transport protein particle (TRAPP) component 40S_SA_C PF16122.5 KFP00392.1 - 8.8e-28 97.5 22.1 1.5e-27 96.7 22.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Ribosomal_S2 PF00318.20 KFP00392.1 - 1.5e-26 93.0 0.0 1.6e-13 50.4 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 TMC PF07810.13 KFP00393.1 - 9.7e-37 126.0 1.9 2.7e-36 124.5 0.8 2.4 2 0 0 2 2 2 1 TMC domain Speriolin_N PF15058.6 KFP00393.1 - 0.0079 16.3 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 Speriolin N terminus TRAP_beta PF05753.14 KFP00393.1 - 0.082 12.3 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Translocon-associated protein beta (TRAPB) SieB PF14163.6 KFP00393.1 - 0.22 11.0 4.0 5.2 6.5 0.1 3.6 4 0 0 4 4 4 0 Super-infection exclusion protein B DDHD PF02862.17 KFP00393.1 - 0.22 11.7 6.8 0.22 11.7 2.9 2.3 2 0 0 2 2 2 0 DDHD domain Ctr PF04145.15 KFP00393.1 - 0.51 11.0 14.5 5.8 7.5 0.0 5.2 4 2 0 4 4 4 0 Ctr copper transporter family FYVE_2 PF02318.16 KFP00394.1 - 7.3e-24 84.3 22.2 7.9e-24 84.1 22.2 1.0 1 0 0 1 1 1 1 FYVE-type zinc finger Siva PF05458.12 KFP00394.1 - 0.25 11.0 16.5 0.28 10.9 16.5 1.0 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Rab_eff_C PF04698.12 KFP00395.1 - 0 1262.6 24.0 0 1262.4 24.0 1.0 1 0 0 1 1 1 1 Rab effector MyRIP/melanophilin C-terminus 53-BP1_Tudor PF09038.10 KFP00395.1 - 0.061 13.3 0.0 4 7.4 0.0 2.4 2 0 0 2 2 2 0 Tumour suppressor p53-binding protein-1 Tudor Macoilin PF09726.9 KFP00395.1 - 8 4.9 21.7 0.07 11.7 12.7 1.9 2 0 0 2 2 2 0 Macoilin family SUI1 PF01253.22 KFP00396.1 - 2.8e-29 101.4 1.0 3.4e-29 101.2 1.0 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF2729 PF10870.8 KFP00396.1 - 0.38 10.6 4.1 1.3 9.0 4.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2729) Gastrin PF00918.17 KFP00397.1 - 4.9e-50 169.7 0.0 5.4e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Gastrin/cholecystokinin family HAP1_N PF04849.13 KFP00398.1 - 2.5e-136 453.9 38.2 3.4e-136 453.5 38.2 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Milton PF12448.8 KFP00398.1 - 4.4e-66 222.3 7.4 4.4e-66 222.3 7.4 2.6 3 0 0 3 3 3 1 Kinesin associated protein KASH_CCD PF14662.6 KFP00398.1 - 0.003 17.4 39.1 0.0071 16.2 13.0 3.4 1 1 2 3 3 3 2 Coiled-coil region of CCDC155 or KASH BSD PF03909.17 KFP00398.1 - 0.43 10.6 1.8 4.5 7.4 0.1 3.0 2 0 0 2 2 2 0 BSD domain Mod_r PF07200.13 KFP00398.1 - 0.68 10.0 32.1 0.67 10.0 10.1 3.6 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Rootletin PF15035.6 KFP00398.1 - 1.8 8.5 39.1 0.16 12.0 7.6 3.3 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion ATG16 PF08614.11 KFP00398.1 - 2.1 8.5 36.5 4.5 7.4 22.9 2.8 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Shugoshin_N PF07558.11 KFP00398.1 - 2.7 7.9 9.3 3.2 7.7 0.3 3.9 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region YabA PF06156.13 KFP00398.1 - 3.8 8.2 29.4 4.7 7.9 3.2 4.5 2 1 2 4 4 4 0 Initiation control protein YabA DUF1664 PF07889.12 KFP00398.1 - 5.3 7.1 17.6 0.23 11.5 1.2 3.7 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 KFP00398.1 - 8.7 5.3 23.9 22 4.0 5.5 2.7 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CorA PF01544.18 KFP00398.1 - 9.6 5.4 18.7 0.98 8.7 8.6 2.9 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein DUF3361 PF11841.8 KFP00399.1 - 0.057 13.4 5.7 0.025 14.5 2.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) Arm PF00514.23 KFP00400.1 - 2e-44 148.3 18.6 9e-08 31.9 0.1 12.3 13 0 0 13 13 13 7 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KFP00400.1 - 1.4e-08 34.9 1.4 0.0058 16.7 0.3 4.4 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFP00400.1 - 6.2e-07 29.2 2.1 12 6.5 0.0 6.0 5 0 0 5 5 5 1 HEAT repeat Adaptin_N PF01602.20 KFP00400.1 - 1.5e-06 27.1 2.1 0.00085 18.0 1.1 3.2 3 0 0 3 3 3 2 Adaptin N terminal region HEAT_2 PF13646.6 KFP00400.1 - 1.5e-06 28.5 6.6 0.029 14.8 0.4 5.1 4 1 1 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 KFP00400.1 - 1.7e-05 25.2 8.2 0.64 10.6 0.3 6.3 4 2 2 6 6 6 2 HEAT-like repeat KAP PF05804.12 KFP00400.1 - 0.00013 20.3 1.4 0.033 12.3 0.0 3.4 1 1 1 3 3 3 1 Kinesin-associated protein (KAP) DUF3361 PF11841.8 KFP00400.1 - 0.00056 19.9 2.3 1.7 8.6 0.0 4.7 2 1 1 4 4 4 1 Domain of unknown function (DUF3361) Atx10homo_assoc PF09759.9 KFP00400.1 - 0.0016 18.4 2.0 0.018 15.0 0.2 3.5 3 2 1 4 4 4 1 Spinocerebellar ataxia type 10 protein domain RasGEF_N_2 PF14663.6 KFP00400.1 - 0.005 17.2 6.8 6.2 7.3 0.0 5.0 5 2 1 6 6 5 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arm_2 PF04826.13 KFP00400.1 - 0.013 15.0 3.8 0.61 9.5 0.0 3.6 2 1 1 3 3 3 0 Armadillo-like Queuosine_synth PF02547.15 KFP00400.1 - 0.017 14.2 0.5 0.037 13.1 0.1 1.7 2 0 0 2 2 2 0 Queuosine biosynthesis protein Yae1_N PF09811.9 KFP00401.1 - 7.7e-18 63.9 63.5 1.8e+04 -28.3 63.5 6.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal DUF4604 PF15377.6 KFP00402.1 - 2.5e-16 60.6 17.9 3.1e-16 60.3 17.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Asp-B-Hydro_N PF05279.11 KFP00402.1 - 0.061 13.4 8.4 0.064 13.3 8.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region EF-1_beta_acid PF10587.9 KFP00402.1 - 2.2 8.8 0.0 2.2 8.8 0.0 4.0 5 0 0 5 5 5 0 Eukaryotic elongation factor 1 beta central acidic region Transglut_N PF00868.20 KFP00403.1 - 3.2e-32 111.3 0.0 8.5e-32 110.0 0.0 1.8 1 0 0 1 1 1 1 Transglutaminase family Transglut_C PF00927.22 KFP00403.1 - 3.1e-16 59.4 0.1 2.9e-11 43.5 0.0 2.4 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 KFP00403.1 - 2.2e-13 50.7 0.0 5.1e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily DHHC PF01529.20 KFP00404.1 - 3.7e-37 127.4 14.2 3.7e-37 127.4 14.2 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF3615 PF12274.8 KFP00404.1 - 0.0036 17.8 0.9 0.0068 16.9 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3615) IGFBP PF00219.18 KFP00404.1 - 2.1 9.1 13.7 34 5.2 10.5 2.4 2 0 0 2 2 2 0 Insulin-like growth factor binding protein RNase_PH PF01138.21 KFP00405.1 - 2.2e-23 83.2 0.0 3.6e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFP00405.1 - 1.2e-11 44.5 0.1 3.1e-11 43.1 0.1 1.8 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Lectin_C PF00059.21 KFP00406.1 - 1.5e-18 67.5 0.1 1.9e-18 67.2 0.1 1.1 1 0 0 1 1 1 1 Lectin C-type domain DUF333 PF03891.15 KFP00406.1 - 0.0039 17.4 0.3 1.8 8.8 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF333) Chordopox_A33R PF05966.12 KFP00406.1 - 0.0083 15.4 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 Chordopoxvirus A33R protein CUB PF00431.20 KFP00407.1 - 9.6e-05 22.7 0.0 2.1 8.7 0.0 4.2 4 0 0 4 4 4 2 CUB domain tRNA-synt_1 PF00133.22 KFP00408.1 - 7e-49 166.6 3.0 1.2e-23 83.2 6.9 6.0 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KFP00408.1 - 2e-31 109.1 0.0 1.6e-20 73.3 0.0 3.5 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KFP00408.1 - 8.2e-13 48.6 0.3 1.8e-12 47.5 0.3 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 KFP00408.1 - 8.4e-09 35.2 0.0 1.3e-06 28.1 0.0 2.5 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KFP00408.1 - 0.0011 18.3 0.0 0.93 8.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 KFP00408.1 - 0.0077 15.2 0.0 0.48 9.3 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (K) LIM PF00412.22 KFP00409.1 - 1.2e-32 111.9 34.2 2.5e-12 46.8 5.5 3.2 3 0 0 3 3 3 3 LIM domain Syja_N PF02383.18 KFP00410.1 - 5.2e-94 315.2 0.7 6.8e-94 314.8 0.7 1.1 1 0 0 1 1 1 1 SacI homology domain LSM PF01423.22 KFP00411.1 - 3.8e-19 68.1 0.7 5.8e-19 67.6 0.7 1.3 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KFP00411.1 - 0.0095 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Hfq protein Gemin7 PF11095.8 KFP00411.1 - 0.045 13.6 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) SM-ATX PF14438.6 KFP00411.1 - 0.047 13.8 0.1 0.069 13.3 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain API5 PF05918.11 KFP00411.1 - 1.6 7.4 3.3 2.2 7.0 3.3 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) SNF PF00209.18 KFP00412.1 - 7.4e-176 585.9 30.4 9.4e-176 585.5 30.4 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Leu_zip PF15294.6 KFP00413.1 - 3.5e-122 407.2 32.0 3.9e-122 407.1 32.0 1.0 1 0 0 1 1 1 1 Leucine zipper RBD PF02196.15 KFP00413.1 - 0.0081 16.2 0.3 0.06 13.4 0.1 2.5 2 1 0 2 2 2 1 Raf-like Ras-binding domain DUF4407 PF14362.6 KFP00413.1 - 1.7 7.9 14.2 24 4.1 14.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 KFP00413.1 - 7.7 5.3 29.7 0.74 8.6 15.5 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein Avidin PF01382.17 KFP00414.1 - 9.1e-14 51.9 1.1 9.4e-14 51.9 1.1 1.0 1 0 0 1 1 1 1 Avidin family ELM2 PF01448.24 KFP00415.1 - 5.1e-11 43.2 0.1 1.5e-10 41.7 0.1 1.8 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-binding PF00249.31 KFP00415.1 - 2.4e-05 24.4 0.1 5e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFP00415.1 - 0.0048 16.8 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 Myb DNA-binding like DUF2890 PF11081.8 KFP00415.1 - 0.54 10.4 2.7 0.84 9.7 1.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2890) 7tm_4 PF13853.6 KFP00416.1 - 1.1e-27 97.6 3.9 1.2e-27 97.4 3.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP00416.1 - 1.8e-08 34.0 5.1 2.9e-08 33.4 5.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2417 PF10329.9 KFP00416.1 - 0.11 11.9 2.3 0.14 11.6 2.3 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) dUTPase PF00692.19 KFP00418.1 - 3.2e-16 59.2 0.0 4.2e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 dUTPase RVP PF00077.20 KFP00418.1 - 0.022 15.0 0.1 0.046 14.0 0.1 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KFP00418.1 - 0.064 13.9 0.5 0.22 12.2 0.1 2.0 2 0 0 2 2 2 0 Aspartyl protease Ribosomal_L22 PF00237.19 KFP00419.1 - 4.1e-49 165.1 0.1 6.2e-49 164.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF4512 PF14975.6 KFP00420.1 - 3.3e-17 63.1 1.7 3.3e-17 63.0 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4512) EF-hand_6 PF13405.6 KFP00421.1 - 2.3e-06 27.1 2.2 1.3e-05 24.8 0.3 2.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 KFP00421.1 - 4.4e-06 25.9 4.8 4.7e-06 25.8 0.7 2.7 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 KFP00421.1 - 1.2e-05 25.0 3.6 0.00049 19.9 0.5 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 KFP00421.1 - 3.4e-05 24.2 0.4 5.4e-05 23.5 0.1 1.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KFP00421.1 - 0.00012 21.5 0.9 0.00012 21.5 0.9 2.1 2 0 0 2 2 2 1 EF hand AAA PF00004.29 KFP00422.1 - 8.5e-97 320.7 0.0 3.9e-47 160.0 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFP00422.1 - 6.8e-28 96.2 6.7 3.1e-13 49.3 0.2 3.2 3 0 0 3 3 2 2 AAA+ lid domain RuvB_N PF05496.12 KFP00422.1 - 5.4e-14 52.2 0.0 1.4e-05 24.9 0.0 3.1 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFP00422.1 - 1.9e-13 51.2 5.2 4.7e-05 23.8 0.1 5.0 4 2 1 5 5 4 2 AAA ATPase domain CDC48_2 PF02933.17 KFP00422.1 - 1.1e-12 47.5 0.0 2.3e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.6 KFP00422.1 - 9.3e-11 42.1 0.0 4.5e-05 23.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 KFP00422.1 - 1.1e-10 41.9 0.0 3.4e-05 24.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KFP00422.1 - 1.3e-10 41.5 0.4 3.9e-05 23.7 0.0 3.4 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFP00422.1 - 1.1e-09 38.7 0.3 0.012 15.9 0.1 4.0 2 2 1 3 3 3 2 AAA domain Vps4_C PF09336.10 KFP00422.1 - 5.5e-09 35.9 0.9 2.6e-05 24.1 0.1 2.7 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain TIP49 PF06068.13 KFP00422.1 - 8.1e-09 35.1 0.0 0.0011 18.3 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 KFP00422.1 - 7.2e-08 33.0 0.0 0.014 15.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KFP00422.1 - 1.3e-07 31.9 0.0 0.0057 17.0 0.0 3.1 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.21 KFP00422.1 - 2.6e-07 30.2 0.2 0.016 14.6 0.0 2.6 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KFP00422.1 - 4.6e-07 29.9 0.0 0.02 14.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KFP00422.1 - 5e-07 29.6 0.1 0.046 13.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Parvo_NS1 PF01057.17 KFP00422.1 - 2.7e-06 26.7 0.1 0.031 13.4 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KFP00422.1 - 3.9e-06 27.2 0.4 0.16 12.2 0.0 3.1 4 0 0 4 4 2 2 AAA domain ATPase PF06745.13 KFP00422.1 - 3.9e-06 26.4 0.1 0.41 9.9 0.0 3.4 3 0 0 3 3 3 2 KaiC AAA_7 PF12775.7 KFP00422.1 - 4.8e-06 26.2 0.0 0.06 12.9 0.0 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 KFP00422.1 - 5.6e-06 26.4 0.2 0.22 11.4 0.0 3.6 2 2 1 3 3 3 2 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 KFP00422.1 - 6.3e-06 26.2 0.0 0.076 12.8 0.0 3.0 3 1 0 3 3 3 2 Bacterial dnaA protein ABC_tran PF00005.27 KFP00422.1 - 6.3e-06 26.7 0.1 0.0086 16.6 0.0 3.5 3 1 0 3 3 2 1 ABC transporter AAA_25 PF13481.6 KFP00422.1 - 1e-05 25.2 2.3 1.4 8.5 0.1 3.6 2 2 0 3 3 3 2 AAA domain DUF815 PF05673.13 KFP00422.1 - 1.1e-05 24.8 0.0 0.01 15.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_24 PF13479.6 KFP00422.1 - 2.8e-05 23.9 0.0 0.071 12.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain TsaE PF02367.17 KFP00422.1 - 4.9e-05 23.3 0.0 0.25 11.3 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 KFP00422.1 - 5.3e-05 23.7 0.0 0.81 10.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 KFP00422.1 - 6.9e-05 22.6 0.0 0.37 10.5 0.0 2.9 2 2 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.12 KFP00422.1 - 8.5e-05 22.5 0.1 0.29 11.0 0.0 3.6 3 1 0 4 4 4 1 NACHT domain Viral_helicase1 PF01443.18 KFP00422.1 - 0.00011 22.0 0.0 0.0016 18.2 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 KFP00422.1 - 0.00024 20.4 0.0 0.19 10.9 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain Zeta_toxin PF06414.12 KFP00422.1 - 0.00038 19.8 0.0 0.45 9.8 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_3 PF07726.11 KFP00422.1 - 0.00056 19.8 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 KFP00422.1 - 0.00059 19.9 0.0 0.068 13.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KFP00422.1 - 0.00077 18.8 0.0 0.34 10.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 KFP00422.1 - 0.00097 19.3 0.0 2.1 8.4 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.16 KFP00422.1 - 0.001 18.6 0.5 1.5 8.2 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.6 KFP00422.1 - 0.0021 17.9 0.2 2 8.2 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.6 KFP00422.1 - 0.0021 18.4 0.3 2.6 8.4 0.1 3.0 2 1 0 3 3 2 1 AAA domain Rad17 PF03215.15 KFP00422.1 - 0.0043 17.0 0.0 0.87 9.5 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_30 PF13604.6 KFP00422.1 - 0.019 14.7 0.4 2.6 7.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KFP00422.1 - 0.025 14.5 0.2 4.6 7.1 0.0 3.1 3 0 0 3 3 3 0 NTPase Cytidylate_kin PF02224.18 KFP00422.1 - 0.033 13.9 0.0 8.2 6.1 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase SKI PF01202.22 KFP00422.1 - 0.06 13.5 1.3 4.9 7.3 0.0 2.8 3 0 0 3 3 2 0 Shikimate kinase Zot PF05707.12 KFP00422.1 - 0.077 12.6 0.0 1.2 8.7 0.0 2.6 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) KAP_NTPase PF07693.14 KFP00422.1 - 0.11 11.8 0.1 3.5 6.8 0.0 2.8 2 2 1 3 3 3 0 KAP family P-loop domain PduV-EutP PF10662.9 KFP00422.1 - 0.11 12.2 0.0 2.9 7.6 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 KFP00422.1 - 0.11 11.8 0.0 11 5.4 0.0 2.9 3 0 0 3 3 2 0 Bacterial TniB protein AAA_23 PF13476.6 KFP00422.1 - 0.16 12.5 0.3 13 6.2 0.0 2.8 3 0 0 3 3 2 0 AAA domain Adap_comp_sub PF00928.21 KFP00423.1 - 9.8e-81 271.0 0.1 1.6e-80 270.3 0.0 1.3 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Choline_transpo PF04515.12 KFP00424.1 - 4e-107 358.2 32.9 4e-107 358.2 32.9 2.7 3 0 0 3 3 3 2 Plasma-membrane choline transporter Renin_r PF07850.14 KFP00424.1 - 0.098 13.3 0.2 0.098 13.3 0.2 3.5 3 1 1 4 4 4 0 Renin receptor-like protein DZF PF07528.14 KFP00425.1 - 6.3e-103 343.7 0.0 1.1e-102 342.9 0.0 1.4 1 0 0 1 1 1 1 DZF domain dsrm PF00035.26 KFP00425.1 - 4.3e-26 91.4 0.1 3.8e-13 50.0 0.1 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KFP00425.1 - 0.00046 20.4 1.0 0.97 9.7 0.1 3.3 2 2 0 2 2 2 2 double strand RNA binding domain from DEAD END PROTEIN 1 BSP_II PF05432.11 KFP00425.1 - 0.005 16.6 0.0 0.005 16.6 0.0 2.0 3 0 0 3 3 3 1 Bone sialoprotein II (BSP-II) TbpB_B_D PF01298.18 KFP00425.1 - 0.0075 16.7 0.2 2.1 8.8 0.0 2.4 1 1 1 2 2 2 2 C-lobe and N-lobe beta barrels of Tf-binding protein B Dynamin_M PF01031.20 KFP00426.1 - 1.8e-108 362.1 0.9 1.8e-108 362.1 0.9 2.2 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.23 KFP00426.1 - 1e-41 142.8 0.0 2.4e-41 141.6 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KFP00426.1 - 8.7e-26 89.9 1.5 2.2e-25 88.6 1.5 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain zf-H2C2_2 PF13465.6 KFP00427.1 - 4.7e-44 146.9 37.1 2.6e-09 37.1 0.1 6.1 6 0 0 6 6 6 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFP00427.1 - 3.1e-30 102.9 41.0 7.8e-06 26.1 0.4 6.1 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP00427.1 - 1.9e-21 74.9 36.8 0.0013 19.4 0.1 6.1 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP00427.1 - 6.8e-18 64.5 9.9 0.02 15.2 1.4 6.2 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFP00427.1 - 4.2e-12 45.4 15.9 0.17 11.5 0.1 6.2 6 0 0 6 6 6 5 Ubiquitin-Binding Zinc Finger zinc_ribbon_9 PF14369.6 KFP00427.1 - 3.3e-10 40.0 20.9 0.066 13.5 0.0 6.2 6 0 0 6 6 6 3 zinc-ribbon XPA_N PF01286.18 KFP00427.1 - 6.6e-10 38.9 16.7 0.11 12.6 0.1 6.1 6 0 0 6 6 6 3 XPA protein N-terminal Zn-ribbon_8 PF09723.10 KFP00427.1 - 9.5e-10 38.4 25.5 0.00071 19.6 1.0 5.0 3 2 2 5 5 5 4 Zinc ribbon domain zf-C2H2_11 PF16622.5 KFP00427.1 - 1.1e-08 34.6 27.5 0.0024 17.6 0.4 6.1 6 0 0 6 6 6 2 zinc-finger C2H2-type zf-LYAR PF08790.11 KFP00427.1 - 7.9e-08 32.1 25.2 0.058 13.3 0.1 6.2 6 0 0 6 6 6 3 LYAR-type C2HC zinc finger zf-ribbon_3 PF13248.6 KFP00427.1 - 1.8e-06 27.1 20.7 0.89 9.1 0.2 6.2 6 0 0 6 6 6 2 zinc-ribbon domain zf-Di19 PF05605.12 KFP00427.1 - 4e-06 27.0 23.3 0.0033 17.7 1.4 4.3 2 1 3 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding TFIIS_C PF01096.18 KFP00427.1 - 1.5e-05 24.8 20.2 4.4 7.2 0.1 6.3 6 0 0 6 6 6 0 Transcription factor S-II (TFIIS) Zn_ribbon_SprT PF17283.2 KFP00427.1 - 4.2e-05 23.4 29.7 0.18 11.7 4.0 5.5 3 2 2 5 5 5 3 SprT-like zinc ribbon domain zf-met PF12874.7 KFP00427.1 - 6.9e-05 23.1 28.0 0.17 12.3 0.0 5.9 6 0 0 6 6 6 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFP00427.1 - 9.7e-05 22.3 40.8 0.35 10.9 0.5 6.6 6 1 0 6 6 6 3 C2H2-type zinc finger DZR PF12773.7 KFP00427.1 - 0.00011 22.1 23.7 2.2e+03 -1.3 23.7 3.9 1 1 0 1 1 1 0 Double zinc ribbon zf-HIT PF04438.16 KFP00427.1 - 0.00019 21.2 26.8 0.62 10.0 0.3 6.1 6 0 0 6 6 6 2 HIT zinc finger zf-trcl PF13451.6 KFP00427.1 - 0.00022 21.0 20.5 1.2 9.0 0.1 6.0 4 2 2 6 6 6 1 Probable zinc-ribbon domain zf-RING_7 PF02591.15 KFP00427.1 - 0.0018 18.4 20.7 1.7 8.9 0.2 5.9 6 0 0 6 6 6 1 C4-type zinc ribbon domain ADK_lid PF05191.14 KFP00427.1 - 0.0018 18.2 20.6 1.4 9.0 0.6 4.8 3 2 0 3 3 3 1 Adenylate kinase, active site lid HypA PF01155.19 KFP00427.1 - 0.0026 17.7 17.7 0.46 10.5 0.4 4.0 1 1 3 4 4 4 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 KFP00427.1 - 0.0033 17.3 19.8 0.7 9.9 1.7 5.6 5 1 0 5 5 5 1 zinc-ribbon domain GAGA PF09237.11 KFP00427.1 - 0.0044 16.8 0.0 0.0044 16.8 0.0 3.9 2 2 2 4 4 4 1 GAGA factor FYDLN_acid PF09538.10 KFP00427.1 - 0.0046 17.6 12.3 16 6.3 0.2 5.4 2 1 2 4 4 4 0 Protein of unknown function (FYDLN_acid) DNA_RNApol_7kD PF03604.13 KFP00427.1 - 0.0053 16.4 17.7 16 5.3 0.2 6.1 6 0 0 6 6 6 0 DNA directed RNA polymerase, 7 kDa subunit Zn_Tnp_IS1595 PF12760.7 KFP00427.1 - 0.0055 16.7 32.8 0.0057 16.6 1.7 4.5 3 2 0 3 3 3 1 Transposase zinc-ribbon domain zinc_ribbon_15 PF17032.5 KFP00427.1 - 0.0069 17.1 19.8 0.27 12.0 3.7 3.6 1 1 0 2 2 2 1 zinc-ribbon family HalOD2 PF18547.1 KFP00427.1 - 0.015 15.2 21.1 0.31 11.0 1.5 5.2 4 1 1 5 5 5 0 Halobacterial output domain 2 zf-AN1 PF01428.16 KFP00427.1 - 0.045 13.9 32.6 8.9 6.6 0.2 6.3 4 1 2 6 6 6 0 AN1-like Zinc finger YhfH PF14149.6 KFP00427.1 - 0.082 12.9 32.9 5 7.2 0.1 6.5 5 1 1 6 6 6 0 YhfH-like protein DUF2256 PF10013.9 KFP00427.1 - 0.099 12.8 17.4 26 5.0 0.1 6.0 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF3268 PF11672.8 KFP00427.1 - 0.11 12.8 15.2 0.36 11.2 1.4 3.7 1 1 2 4 4 4 0 zinc-finger-containing domain zinc-ribbons_6 PF07191.12 KFP00427.1 - 0.12 12.4 22.0 66 3.6 9.3 4.7 1 1 2 3 3 3 0 zinc-ribbons DUF1272 PF06906.11 KFP00427.1 - 0.29 11.3 0.1 0.29 11.3 0.1 5.1 4 1 1 5 5 5 0 Protein of unknown function (DUF1272) zf-C2HC_2 PF13913.6 KFP00427.1 - 0.39 10.7 0.2 0.39 10.7 0.2 5.8 6 0 0 6 6 6 0 zinc-finger of a C2HC-type LIM PF00412.22 KFP00427.1 - 0.43 10.8 19.8 1.3 9.3 1.8 4.7 1 1 4 5 5 5 0 LIM domain CpXC PF14353.6 KFP00427.1 - 0.44 10.6 22.9 6.9 6.7 0.2 5.7 1 1 4 5 5 5 0 CpXC protein zf-C2H2_9 PF16293.5 KFP00427.1 - 0.97 9.3 0.0 0.97 9.3 0.0 4.2 4 2 2 6 6 6 0 C2H2 type zinc-finger (1 copy) zf-C2HE PF16278.5 KFP00427.1 - 1.2 9.7 27.3 8.1 7.0 0.1 5.8 1 1 5 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger TF_Zn_Ribbon PF08271.12 KFP00427.1 - 1.9 8.1 27.4 2.9 7.5 0.4 5.7 5 1 0 5 5 5 0 TFIIB zinc-binding zinc_ribbon_10 PF10058.9 KFP00427.1 - 1.9 8.3 19.5 35 4.2 0.1 5.9 6 0 0 6 6 6 0 Predicted integral membrane zinc-ribbon metal-binding protein Rubredoxin_2 PF18073.1 KFP00427.1 - 2.1 8.1 28.7 12 5.7 0.4 6.3 6 0 0 6 6 6 0 Rubredoxin metal binding domain Ribosomal_L37ae PF01780.19 KFP00427.1 - 3 8.0 23.0 25 5.1 0.4 5.7 2 1 3 5 5 5 0 Ribosomal L37ae protein family zinc_ribbon_5 PF13719.6 KFP00427.1 - 4 7.3 20.5 10 6.0 0.1 5.3 5 1 0 5 5 5 0 zinc-ribbon domain zf-H2C2_5 PF13909.6 KFP00427.1 - 4.1 7.2 0.0 4.1 7.2 0.0 8.9 10 1 0 10 10 9 0 C2H2-type zinc-finger domain HNH PF01844.23 KFP00427.1 - 8.4 6.7 29.1 0.44 10.8 0.4 5.9 6 0 0 6 6 6 0 HNH endonuclease Ogr_Delta PF04606.12 KFP00427.1 - 9.7 6.3 21.7 10 6.2 0.1 5.3 4 2 1 5 5 5 0 Ogr/Delta-like zinc finger RVT_1 PF00078.27 KFP00428.1 - 0.0055 16.3 0.0 0.0087 15.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD-3 PF09765.9 KFP00429.1 - 1.1e-106 356.3 0.5 1.3e-106 356.1 0.5 1.0 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.8 KFP00429.1 - 1.5e-30 105.1 4.3 3.1e-30 104.1 4.3 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 KFP00429.1 - 7.4e-06 26.2 3.4 2.1e-05 24.8 3.4 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFP00429.1 - 0.037 14.3 3.5 0.11 12.8 3.5 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-HC5HC2H PF13771.6 KFP00429.1 - 0.038 14.2 0.5 0.073 13.3 0.5 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-ANAPC11 PF12861.7 KFP00429.1 - 0.05 13.6 3.6 0.19 11.8 3.6 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 KFP00429.1 - 0.2 11.8 1.7 0.39 10.9 1.7 1.6 1 0 0 1 1 1 0 RING-variant domain Yae1_N PF09811.9 KFP00431.1 - 1.4e-14 53.4 46.7 1.8e+04 -11.6 46.7 4.6 1 1 0 1 1 1 0 Essential protein Yae1, N terminal CCDC85 PF10226.9 KFP00432.1 - 3.8e-95 317.1 13.8 1.5e-94 315.2 12.4 2.2 2 0 0 2 2 2 1 CCDC85 family AMH_N PF04709.12 KFP00432.1 - 0.0055 15.7 0.8 0.0055 15.7 0.8 2.1 1 1 1 2 2 2 1 Anti-Mullerian hormone, N terminal region Cast PF10174.9 KFP00432.1 - 0.043 12.1 8.7 0.013 13.8 5.9 1.4 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone TSC22 PF01166.18 KFP00432.1 - 0.049 13.9 9.8 2.9 8.3 0.1 3.9 3 0 0 3 3 3 0 TSC-22/dip/bun family Vir_act_alpha_C PF10400.9 KFP00432.1 - 0.31 11.7 0.2 0.31 11.7 0.2 2.2 3 0 0 3 3 3 0 Virulence activator alpha C-term bZIP_1 PF00170.21 KFP00432.1 - 0.36 11.0 0.1 0.36 11.0 0.1 3.4 3 0 0 3 3 3 0 bZIP transcription factor Shugoshin_N PF07558.11 KFP00432.1 - 1.4 8.8 5.9 3.6 7.5 1.4 2.5 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region YabA PF06156.13 KFP00432.1 - 7.3 7.3 9.3 11 6.7 0.4 3.5 2 1 1 3 3 3 0 Initiation control protein YabA EGF_CA PF07645.15 KFP00433.1 - 2.3e-48 162.1 90.8 4.2e-14 52.5 7.2 8.0 8 0 0 8 8 8 6 Calcium-binding EGF domain cEGF PF12662.7 KFP00433.1 - 3.6e-37 125.9 50.2 2.4e-10 40.1 0.6 7.4 7 0 0 7 7 7 6 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFP00433.1 - 8e-10 38.8 53.5 6.4e-07 29.6 6.9 8.0 8 1 0 8 8 8 4 Coagulation Factor Xa inhibitory site EGF PF00008.27 KFP00433.1 - 2.5e-07 30.9 90.7 0.00041 20.6 8.7 8.8 9 2 1 10 10 10 5 EGF-like domain EGF_3 PF12947.7 KFP00433.1 - 0.00012 22.2 8.5 0.00012 22.2 8.5 8.4 8 2 0 8 8 8 4 EGF domain EGF_MSP1_1 PF12946.7 KFP00433.1 - 0.00047 20.2 47.1 0.034 14.2 1.6 6.6 5 1 1 6 6 6 3 MSP1 EGF domain 1 hEGF PF12661.7 KFP00433.1 - 0.00077 20.0 2.1 0.00077 20.0 2.1 10.9 12 1 1 13 13 13 5 Human growth factor-like EGF ARL2_Bind_BART PF11527.8 KFP00434.1 - 2.7e-25 88.7 4.8 2.7e-25 88.7 4.8 1.5 2 0 0 2 2 2 1 The ARF-like 2 binding protein BART Reticulon PF02453.17 KFP00434.1 - 0.14 12.1 0.1 0.22 11.4 0.1 1.2 1 0 0 1 1 1 0 Reticulon HOOK PF05622.12 KFP00435.1 - 1.4e-35 122.6 69.3 1.4e-35 122.6 69.3 5.9 1 1 3 5 5 5 2 HOOK protein APG6_N PF17675.1 KFP00435.1 - 0.00046 20.7 47.7 0.0012 19.4 12.6 15.3 2 1 11 14 14 14 4 Apg6 coiled-coil region DUF4472 PF14739.6 KFP00435.1 - 0.0033 18.1 15.5 0.0033 18.1 15.5 15.1 4 3 11 16 16 16 3 Domain of unknown function (DUF4472) GAS PF13851.6 KFP00435.1 - 0.0041 16.5 30.7 0.0041 16.5 30.7 12.4 1 1 10 12 12 12 5 Growth-arrest specific micro-tubule binding tRNA_edit PF04073.15 KFP00436.1 - 3.2e-25 88.6 0.0 3.6e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain GTP_EFTU PF00009.27 KFP00437.1 - 1.7e-32 112.5 3.1 1.7e-32 112.5 3.1 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KFP00437.1 - 1.9e-32 111.5 2.0 7e-32 109.7 2.0 2.0 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KFP00437.1 - 1.2e-09 38.2 0.4 3.4e-09 36.8 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.21 KFP00437.1 - 5.9e-05 22.6 0.0 0.00022 20.7 0.0 1.9 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU_D4 PF14578.6 KFP00437.1 - 0.00069 19.5 0.4 0.015 15.2 0.1 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Ras PF00071.22 KFP00437.1 - 0.00075 19.1 0.0 0.0025 17.4 0.0 1.9 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFP00437.1 - 0.0015 18.0 0.2 0.016 14.7 0.2 2.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KFP00437.1 - 0.0021 17.6 0.1 0.0071 15.9 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 KFP00437.1 - 0.0031 17.5 1.8 2.5 8.1 0.4 2.6 2 0 0 2 2 2 2 C-terminal region of MMR_HSR1 domain Roc PF08477.13 KFP00437.1 - 0.0038 17.4 0.0 0.01 16.1 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KFP00437.1 - 0.015 15.4 1.9 2.9 7.9 0.0 3.4 2 1 1 3 3 3 0 Dynamin family AAA_26 PF13500.6 KFP00437.1 - 0.048 13.5 0.1 0.14 11.9 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KFP00437.1 - 1.7 9.1 5.4 5.1 7.5 0.0 3.3 4 0 0 4 4 4 0 AAA domain ubiquitin PF00240.23 KFP00438.1 - 7.7e-35 118.5 0.6 1.2e-34 117.8 0.3 1.5 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 KFP00438.1 - 2.9e-28 97.8 4.1 5.8e-28 96.8 4.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.8 KFP00438.1 - 6.5e-17 61.1 0.4 1.3e-16 60.1 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFP00438.1 - 5.8e-06 26.7 0.3 2.9e-05 24.4 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KFP00438.1 - 0.00014 21.9 0.8 0.0003 20.8 0.8 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KFP00438.1 - 0.0048 16.8 0.1 0.007 16.3 0.1 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KFP00438.1 - 0.008 16.7 0.8 0.011 16.2 0.8 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 KFP00438.1 - 0.0094 16.3 1.2 0.013 15.9 0.0 1.8 1 1 1 2 2 2 1 Ubiquitin-like domain IBR PF01485.21 KFP00438.1 - 0.039 14.2 4.2 0.064 13.5 4.2 1.4 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Ubiquitin_4 PF18036.1 KFP00438.1 - 0.11 12.5 2.7 9.7 6.3 0.0 2.5 3 0 0 3 3 3 0 Ubiquitin-like domain WD40 PF00400.32 KFP00440.1 - 3.7e-67 220.6 85.2 7.2e-05 23.5 0.0 28.2 31 0 0 31 31 31 13 WD domain, G-beta repeat HELP PF03451.14 KFP00440.1 - 3.2e-55 183.9 2.6 2.4e-20 72.2 0.1 3.4 3 0 0 3 3 3 3 HELP motif ANAPC4_WD40 PF12894.7 KFP00440.1 - 6.9e-39 132.0 8.5 1.6e-07 31.5 0.0 12.8 8 3 4 12 12 12 8 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP00440.1 - 4.4e-10 39.0 0.9 0.018 14.0 0.0 7.5 5 3 2 8 8 8 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFP00440.1 - 9.9e-07 28.4 1.4 1.2 8.4 0.0 7.1 7 1 0 8 8 8 2 WD40-like domain Cytochrom_D1 PF02239.16 KFP00440.1 - 1.1e-06 27.5 8.2 0.74 8.3 0.0 6.8 6 1 1 7 7 7 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 KFP00440.1 - 8.4e-06 24.8 0.0 0.025 13.3 0.0 4.3 4 0 0 4 4 4 1 Nup133 N terminal like Frtz PF11768.8 KFP00440.1 - 1e-05 24.1 0.0 0.014 13.7 0.0 4.3 4 1 1 5 5 5 1 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 KFP00440.1 - 2.8e-05 23.9 0.5 49 4.0 0.0 6.8 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 KFP00440.1 - 0.0039 16.3 0.6 9 5.2 0.0 5.0 6 2 1 7 7 7 2 Coatomer WD associated region Nup160 PF11715.8 KFP00440.1 - 0.0046 15.7 0.5 10 4.6 0.0 4.4 4 1 0 5 5 5 1 Nucleoporin Nup120/160 Nbas_N PF15492.6 KFP00440.1 - 0.038 13.3 0.1 19 4.4 0.0 4.2 4 1 1 5 5 5 0 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 KFP00440.1 - 0.11 11.4 0.1 27 3.5 0.0 3.8 4 0 0 4 4 4 0 Partner and localizer of BRCA2 WD40 domain PSII_BNR PF14870.6 KFP00440.1 - 0.15 11.3 1.7 4.4 6.5 0.0 3.3 4 0 0 4 4 4 0 Photosynthesis system II assembly factor YCF48 Spectrin PF00435.21 KFP00441.1 - 0 1067.7 202.0 6.3e-28 97.3 5.2 18.7 19 0 0 19 19 19 17 Spectrin repeat CH PF00307.31 KFP00441.1 - 4.4e-52 174.9 0.5 1.1e-25 89.9 0.1 3.6 2 0 0 2 2 2 2 Calponin homology (CH) domain PH_9 PF15410.6 KFP00441.1 - 2.1e-22 79.7 0.7 1.6e-21 76.9 0.7 2.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFP00441.1 - 5.2e-17 62.3 0.5 5.2e-17 62.3 0.5 2.9 3 0 0 3 3 3 1 PH domain CAMSAP_CH PF11971.8 KFP00441.1 - 6.8e-09 35.4 0.2 1.6e-06 27.8 0.1 3.0 2 0 0 2 2 2 1 CAMSAP CH domain PH_11 PF15413.6 KFP00441.1 - 0.00052 20.4 1.1 0.005 17.3 1.1 2.9 1 0 0 1 1 1 1 Pleckstrin homology domain CENP-K PF11802.8 KFP00441.1 - 0.001 18.7 1.2 0.001 18.7 1.2 8.5 4 3 3 8 8 8 1 Centromere-associated protein K CH_2 PF06294.11 KFP00441.1 - 0.54 10.4 3.9 8.2 6.6 0.0 4.9 4 0 0 4 4 4 0 CH-like domain in sperm protein Acylphosphatase PF00708.18 KFP00442.1 - 1.2e-15 57.7 0.0 1.3e-15 57.6 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase NIL PF09383.10 KFP00442.1 - 0.12 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 NIL domain BLM10_mid PF16507.5 KFP00443.1 - 2.1e-112 376.4 2.1 1.1e-110 370.8 0.5 3.5 3 1 0 3 3 3 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KFP00443.1 - 7.1e-37 125.2 0.1 3.7e-35 119.7 0.0 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.22 KFP00443.1 - 1.5e-05 24.8 0.4 0.6 10.5 0.1 4.6 4 0 0 4 4 4 2 HEAT repeat 7tm_1 PF00001.21 KFP00444.1 - 4.3e-22 78.7 8.7 4.3e-22 78.7 8.7 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP00444.1 - 0.51 9.9 18.5 0.012 15.2 11.7 1.7 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx LRR_8 PF13855.6 KFP00445.1 - 1.1e-34 118.0 48.4 3.1e-09 36.5 1.1 9.8 6 2 4 10 10 10 8 Leucine rich repeat LRR_4 PF12799.7 KFP00445.1 - 3.3e-27 94.1 57.8 8.9e-06 26.0 0.3 10.8 9 2 3 12 12 12 10 Leucine Rich repeats (2 copies) TIR PF01582.20 KFP00445.1 - 7.2e-23 81.3 0.0 1.3e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 KFP00445.1 - 9.3e-19 68.2 0.0 2.2e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.33 KFP00445.1 - 2.5e-05 24.2 44.5 5.8 7.9 0.2 14.6 16 1 0 16 16 16 3 Leucine Rich Repeat LRR_6 PF13516.6 KFP00445.1 - 0.0041 17.1 41.2 4.3 7.6 0.1 12.2 14 0 0 14 14 14 3 Leucine Rich repeat LRR_9 PF14580.6 KFP00445.1 - 0.0058 16.1 14.7 0.98 8.9 0.1 4.7 3 1 2 5 5 5 2 Leucine-rich repeat ChaC PF04752.12 KFP00446.1 - 1.3e-40 139.3 0.0 1.5e-40 139.1 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein Ank_2 PF12796.7 KFP00447.1 - 2.4e-51 172.2 0.1 1.8e-13 50.9 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP00447.1 - 4.2e-42 142.0 0.7 2.3e-09 37.6 0.0 6.9 4 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP00447.1 - 1.1e-35 117.6 0.3 0.00068 19.9 0.0 9.4 9 0 0 9 9 9 8 Ankyrin repeat Ank PF00023.30 KFP00447.1 - 4.2e-35 118.7 1.8 0.00014 22.1 0.0 9.3 8 1 1 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 KFP00447.1 - 1e-32 111.7 1.5 2e-06 27.9 0.0 8.6 1 1 8 9 9 9 7 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFP00447.1 - 2.5e-11 43.7 4.3 5.1e-11 42.7 4.3 1.5 1 0 0 1 1 1 1 SOCS box MARVEL PF01284.23 KFP00448.1 - 6.5e-12 45.7 10.7 7.4e-12 45.5 10.7 1.0 1 0 0 1 1 1 1 Membrane-associating domain Col_cuticle_N PF01484.17 KFP00448.1 - 1.6 8.8 9.1 0.14 12.2 1.1 2.4 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Ion_trans PF00520.31 KFP00449.1 - 2.6e-18 66.1 26.4 3.5e-18 65.7 26.4 1.0 1 0 0 1 1 1 1 Ion transport protein DUF5310 PF17237.2 KFP00449.1 - 1.3 9.0 7.0 12 5.9 7.0 2.5 1 1 0 1 1 1 0 Family of unknown function (DUF5310) Ion_trans PF00520.31 KFP00450.1 - 2.3e-14 53.2 4.5 2.7e-14 53.0 4.5 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KFP00450.1 - 0.036 12.8 1.5 0.06 12.0 1.5 1.3 1 0 0 1 1 1 0 Polycystin cation channel DUF5313 PF17240.2 KFP00450.1 - 0.21 12.1 0.0 0.36 11.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5313) DUF4083 PF13314.6 KFP00450.1 - 1.9 8.5 7.2 0.096 12.6 1.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) SurA_N_2 PF13623.6 KFP00450.1 - 3.1 7.6 9.1 2.3 8.1 0.3 2.5 1 1 1 2 2 2 0 SurA N-terminal domain Cofilin_ADF PF00241.20 KFP00451.1 - 2.1e-32 111.5 0.2 2.6e-32 111.1 0.2 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Rib_recp_KP_reg PF05104.12 KFP00452.1 - 3.8e-30 106.0 44.1 3.8e-30 106.0 44.1 6.2 4 2 2 6 6 6 1 Ribosome receptor lysine/proline rich region Fez1 PF06818.15 KFP00452.1 - 0.0018 18.8 32.4 0.0018 18.8 32.4 6.9 3 1 3 6 6 6 1 Fez1 ABC_export PF16962.5 KFP00452.1 - 0.044 12.2 0.2 0.068 11.6 0.2 1.2 1 0 0 1 1 1 0 Putative ABC exporter PX PF00787.24 KFP00453.1 - 4.3e-19 68.6 4.8 5e-19 68.4 0.3 2.8 3 1 0 3 3 3 1 PX domain Vps5 PF09325.10 KFP00453.1 - 5.5e-17 62.1 18.8 8.2e-16 58.3 13.9 2.5 2 1 0 2 2 2 1 Vps5 C terminal like Glyco_hydro_97 PF10566.9 KFP00453.1 - 0.11 11.8 0.2 0.17 11.1 0.2 1.4 1 0 0 1 1 1 0 Glycoside hydrolase 97 LcrG PF07216.12 KFP00453.1 - 0.13 12.2 0.4 8.1 6.4 0.0 3.0 3 0 0 3 3 3 0 LcrG protein PDDEXK_1 PF12705.7 KFP00454.1 - 8.7e-08 32.4 0.1 6.9e-07 29.4 0.1 2.2 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily zf-C2H2 PF00096.26 KFP00455.1 - 2.6e-18 65.4 26.3 4.4e-05 23.7 2.5 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP00455.1 - 7.3e-18 64.1 23.4 1.8e-09 37.6 0.6 5.2 5 1 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP00455.1 - 4.3e-12 45.8 25.0 0.00025 21.6 1.4 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KFP00455.1 - 4.4e-08 33.8 13.5 3.4e-06 27.8 0.5 3.0 2 1 1 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 KFP00455.1 - 5.5e-06 26.5 10.4 0.38 11.1 0.5 3.8 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP00455.1 - 3.2e-05 24.2 15.8 0.00079 19.7 2.4 4.5 3 1 1 4 4 4 1 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 KFP00455.1 - 0.00017 21.1 0.0 0.00017 21.1 0.0 2.9 2 1 1 3 3 3 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_5 PF13909.6 KFP00455.1 - 0.00053 19.7 20.3 0.12 12.2 0.2 5.3 4 2 1 5 5 5 2 C2H2-type zinc-finger domain FYVE PF01363.21 KFP00455.1 - 0.0089 16.1 20.2 0.2 11.8 10.5 2.6 1 1 1 2 2 2 2 FYVE zinc finger zf-C2H2_12 PF18658.1 KFP00455.1 - 0.073 12.7 0.0 0.073 12.7 0.0 3.4 1 1 3 4 4 4 0 Zinc-finger C2H2-type DUF2256 PF10013.9 KFP00455.1 - 0.16 12.1 6.6 5.8 7.1 0.4 3.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_11 PF16622.5 KFP00455.1 - 0.18 11.6 20.1 0.12 12.1 1.3 4.0 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-MYST PF17772.1 KFP00455.1 - 0.35 10.5 12.8 4.1 7.1 0.1 4.1 4 0 0 4 4 4 0 MYST family zinc finger domain zinc_ribbon_15 PF17032.5 KFP00455.1 - 0.37 11.6 11.6 0.61 10.9 1.4 2.3 1 1 1 2 2 2 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 KFP00455.1 - 0.42 10.8 17.6 4.6 7.4 0.4 4.4 3 1 1 4 4 4 0 Zinc ribbon domain DUF629 PF04780.12 KFP00455.1 - 0.5 8.8 5.1 9 4.7 0.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.7 KFP00455.1 - 0.58 10.5 16.5 2.1 8.8 0.4 3.7 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) XPA_N PF01286.18 KFP00455.1 - 0.61 10.2 9.8 35 4.6 0.2 4.2 4 0 0 4 4 4 0 XPA protein N-terminal A2L_zn_ribbon PF08792.10 KFP00455.1 - 0.66 9.8 0.1 0.66 9.8 0.1 3.9 4 0 0 4 4 4 0 A2L zinc ribbon domain zf_UBZ PF18439.1 KFP00455.1 - 1.2 8.8 11.0 8.4 6.1 0.6 4.2 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 KFP00455.1 - 2.1 8.4 27.6 0.76 9.9 3.3 3.7 4 0 0 4 4 3 0 C2H2-type zinc finger ADK_lid PF05191.14 KFP00455.1 - 2.5 8.2 11.2 0.36 10.8 1.6 3.4 3 1 0 3 3 3 0 Adenylate kinase, active site lid Rpr2 PF04032.16 KFP00455.1 - 2.7 8.3 18.9 1.9 8.8 3.5 3.6 3 1 1 4 4 4 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-dskA_traR PF01258.17 KFP00455.1 - 6.6 6.8 8.6 13 5.9 0.0 3.7 4 0 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger PET117 PF15786.5 KFP00456.1 - 1.2e-07 31.9 1.7 1.3e-07 31.7 1.1 1.4 1 1 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Acetyltransf_1 PF00583.25 KFP00457.1 - 5.5e-10 39.5 0.0 1.1e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFP00457.1 - 1.3e-09 38.1 0.0 2.9e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFP00457.1 - 8.7e-08 32.5 0.0 1.7e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFP00457.1 - 6.8e-05 22.8 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KFP00457.1 - 0.0019 18.3 0.0 0.0039 17.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KFP00457.1 - 0.0084 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase zf_UBZ PF18439.1 KFP00457.1 - 1.3 8.6 4.1 1.1 8.9 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger RNA_pol_Rpc34 PF05158.12 KFP00458.1 - 1.9e-104 349.7 0.5 2.2e-104 349.5 0.5 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit TrmB PF01978.19 KFP00458.1 - 0.00054 19.8 0.7 0.011 15.6 0.2 2.8 2 1 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB RPA_C PF08784.11 KFP00458.1 - 0.0017 19.0 0.7 1.3 9.7 0.0 3.3 3 0 0 3 3 3 1 Replication protein A C terminal CDC24_OB1 PF17246.2 KFP00458.1 - 0.021 15.0 0.1 0.061 13.5 0.0 1.9 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 1 TFIIE_alpha PF02002.17 KFP00458.1 - 0.053 13.4 0.4 0.13 12.1 0.4 1.8 1 0 0 1 1 1 0 TFIIE alpha subunit IPK PF03770.16 KFP00459.1 - 3.4e-44 151.1 0.0 8.1e-44 149.9 0.0 1.6 1 1 0 1 1 1 1 Inositol polyphosphate kinase Retrotrans_gag PF03732.17 KFP00459.1 - 0.22 11.8 1.4 1.6 9.1 0.0 2.6 2 1 0 2 2 2 0 Retrotransposon gag protein Presenilin PF01080.17 KFP00460.1 - 5.1e-157 522.7 20.8 1.1e-110 370.1 11.7 2.2 1 1 1 2 2 2 2 Presenilin ABC1 PF03109.16 KFP00461.1 - 9.4e-34 116.1 0.0 2.3e-33 114.9 0.0 1.7 1 0 0 1 1 1 1 ABC1 family DUF2959 PF11172.8 KFP00461.1 - 0.026 14.7 0.4 0.15 12.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) CNH PF00780.22 KFP00462.1 - 4.5e-76 256.1 0.1 8.4e-76 255.2 0.1 1.5 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.25 KFP00462.1 - 2e-54 184.7 1.7 2.5e-54 184.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain KELK PF15796.5 KFP00462.1 - 1.4e-32 111.9 21.0 1.4e-32 111.9 21.0 7.5 5 3 2 7 7 6 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pkinase_Tyr PF07714.17 KFP00462.1 - 5e-29 101.4 0.0 1.4e-28 99.9 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase DMPK_coil PF08826.10 KFP00462.1 - 3.4e-24 84.7 11.7 3.4e-24 84.7 11.7 9.5 7 4 2 10 10 9 1 DMPK coiled coil domain like C1_1 PF00130.22 KFP00462.1 - 2.2e-11 43.5 8.1 2.2e-11 43.5 8.1 2.0 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 KFP00462.1 - 7.3e-07 28.8 0.0 2.3e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 KFP00462.1 - 7.2e-05 23.4 4.3 7.7e-05 23.3 2.5 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain PH PF00169.29 KFP00462.1 - 0.011 16.3 0.0 0.15 12.6 0.0 2.9 2 0 0 2 2 2 0 PH domain PBD PF00786.28 KFP00462.1 - 0.021 15.2 0.6 0.084 13.2 0.1 2.4 2 0 0 2 2 1 0 P21-Rho-binding domain Seadorna_VP7 PF07387.11 KFP00462.1 - 0.078 12.0 0.2 0.21 10.6 0.2 1.6 1 0 0 1 1 1 0 Seadornavirus VP7 Calici_MSP PF05752.11 KFP00462.1 - 0.23 11.2 2.5 0.99 9.2 2.5 2.2 1 0 0 1 1 1 0 Calicivirus minor structural protein RVT_1 PF00078.27 KFP00463.1 - 5.5e-23 81.6 0.0 6.5e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.22 KFP00464.1 - 3.4e-24 84.5 0.0 5.6e-15 54.9 0.0 2.0 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KFP00464.1 - 1.7e-05 24.8 0.0 2.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Limkain b1 RRM_occluded PF16842.5 KFP00464.1 - 3.6e-05 23.5 0.0 9.6e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KFP00464.1 - 3.7e-05 23.3 0.0 7.6e-05 22.3 0.0 1.6 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP00464.1 - 0.00015 21.8 0.0 0.098 12.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif DbpA PF03880.15 KFP00464.1 - 0.0064 16.5 0.0 0.0086 16.1 0.0 1.2 1 0 0 1 1 1 1 DbpA RNA binding domain Sam68-YY PF16568.5 KFP00465.1 - 1.5e-20 73.7 32.5 2.9e-20 72.8 32.5 1.5 1 0 0 1 1 1 1 Tyrosine-rich domain of Sam68 KH_1 PF00013.29 KFP00465.1 - 3.1e-09 36.5 0.0 5.5e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 KH domain Qua1 PF16274.5 KFP00465.1 - 8.4e-07 28.7 6.1 8.4e-07 28.7 6.1 2.1 2 0 0 2 2 2 1 Qua1 domain Scramblase PF03803.15 KFP00466.1 - 9.5e-82 273.6 0.1 1e-81 273.4 0.1 1.0 1 0 0 1 1 1 1 Scramblase Scramblase PF03803.15 KFP00467.1 - 2.5e-73 246.0 0.1 2.8e-73 245.9 0.1 1.0 1 0 0 1 1 1 1 Scramblase DUF4413 PF14372.6 KFP00467.1 - 0.14 12.5 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) zf_ZIC PF18366.1 KFP00468.1 - 6.2e-28 96.6 6.1 4.3e-27 94.0 0.9 3.0 3 0 0 3 3 3 1 Zic proteins zinc finger domain zf-C2H2 PF00096.26 KFP00468.1 - 3.3e-13 49.3 10.1 3.8e-06 27.1 0.2 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP00468.1 - 3.6e-09 36.6 9.8 5.6e-08 32.9 0.3 4.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP00468.1 - 7.6e-05 23.2 22.5 0.0048 17.6 0.2 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP00468.1 - 0.0021 18.3 3.0 0.17 12.2 0.1 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFP00468.1 - 1.2 9.5 8.7 1.2 9.5 2.1 2.9 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf_ZIC PF18366.1 KFP00469.1 - 5.9e-28 96.7 0.9 5.9e-28 96.7 0.9 3.7 4 0 0 4 4 4 1 Zic proteins zinc finger domain zf-C2H2 PF00096.26 KFP00469.1 - 2e-21 75.2 31.9 8.8e-06 25.9 0.2 5.9 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP00469.1 - 5.7e-20 70.8 29.6 1.3e-07 31.7 0.3 5.6 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP00469.1 - 5.4e-13 48.6 26.8 0.0078 17.0 2.5 6.1 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP00469.1 - 6.1e-06 26.4 14.3 0.11 12.8 0.2 4.9 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP00469.1 - 3.5e-05 23.7 10.3 0.15 12.1 2.8 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFP00469.1 - 0.0012 19.2 14.0 0.003 17.9 1.2 4.6 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFP00469.1 - 0.0019 18.5 12.8 0.076 13.3 2.6 3.3 1 1 2 3 3 3 3 C2H2-type zinc ribbon 7tm_1 PF00001.21 KFP00470.1 - 2.2e-55 187.8 23.4 2.2e-55 187.8 23.4 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP00470.1 - 1.3e-08 34.6 26.5 1.9e-08 34.0 26.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Peptidase_M14 PF00246.24 KFP00471.1 - 1.7e-91 307.0 0.0 2.1e-91 306.7 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KFP00471.1 - 3.8e-20 72.1 0.6 9e-20 70.9 0.4 1.8 2 0 0 2 2 2 1 Carboxypeptidase activation peptide RRM_1 PF00076.22 KFP00472.1 - 1.9e-16 59.7 0.0 2.5e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GFA PF04828.14 KFP00472.1 - 0.079 13.3 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme RRM_occluded PF16842.5 KFP00472.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif Glyco_transf_22 PF03901.17 KFP00473.1 - 9.8e-53 179.9 25.5 1.3e-52 179.5 25.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Transferrin PF00405.17 KFP00474.1 - 4e-227 752.6 9.2 1.3e-120 402.5 0.6 2.0 2 0 0 2 2 2 2 Transferrin Phosphonate-bd PF12974.7 KFP00474.1 - 6.2e-15 55.5 0.0 8.1e-07 28.9 0.0 3.2 2 2 0 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 KFP00474.1 - 0.0013 18.2 0.2 0.63 9.4 0.1 2.8 2 1 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 BKACE PF05853.12 KFP00474.1 - 0.09 12.1 0.0 2.7 7.2 0.0 2.3 2 0 0 2 2 2 0 beta-keto acid cleavage enzyme DUF3991 PF13154.6 KFP00474.1 - 0.1 13.0 0.2 20 5.6 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3991) Guanylate_kin PF00625.21 KFP00475.1 - 5.8e-66 221.7 1.4 9.4e-66 221.0 1.4 1.4 1 0 0 1 1 1 1 Guanylate kinase PDZ PF00595.24 KFP00475.1 - 5.5e-64 212.5 9.0 1.4e-20 73.4 0.2 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 KFP00475.1 - 2e-30 104.4 2.7 6e-11 42.0 0.1 3.8 3 0 0 3 3 3 3 PDZ domain PDZ_assoc PF10600.9 KFP00475.1 - 6.3e-29 100.6 5.1 6.3e-29 100.6 5.1 2.1 2 0 0 2 2 2 1 PDZ-associated domain of NMDA receptors MAGUK_N_PEST PF10608.9 KFP00475.1 - 3.7e-19 69.3 10.7 2.1e-14 54.0 3.4 2.7 1 1 1 2 2 2 2 Polyubiquitination (PEST) N-terminal domain of MAGUK PDZ_2 PF13180.6 KFP00475.1 - 2.6e-18 66.1 2.9 2.9e-05 24.3 0.0 4.0 4 0 0 4 4 4 3 PDZ domain SH3_1 PF00018.28 KFP00475.1 - 2.6e-08 33.3 0.1 7.5e-08 31.9 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP00475.1 - 3.9e-08 32.9 0.0 1e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFP00475.1 - 0.037 13.9 0.0 0.12 12.2 0.0 2.0 1 0 0 1 1 1 0 Variant SH3 domain DUF1638 PF07796.11 KFP00475.1 - 0.09 12.9 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1638) adh_short PF00106.25 KFP00476.1 - 7.9e-42 142.9 0.0 1e-41 142.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP00476.1 - 5.4e-26 91.6 0.0 7.9e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP00476.1 - 1e-07 32.1 0.0 1.6e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFP00476.1 - 1.4e-05 24.6 0.0 5.6e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Lipocalin PF00061.23 KFP00477.1 - 9.5e-22 77.8 0.1 1.1e-21 77.6 0.1 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.12 KFP00477.1 - 5.4e-21 75.1 0.0 8e-21 74.5 0.0 1.3 1 1 0 1 1 1 1 Lipocalin-like domain VDE PF07137.11 KFP00477.1 - 2.7e-06 27.1 0.0 3.5e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 VDE lipocalin domain Triabin PF03973.13 KFP00477.1 - 5.9e-05 23.0 0.3 0.00023 21.0 0.3 1.9 1 1 0 1 1 1 1 Triabin IPP-2 PF04979.14 KFP00478.1 - 3.4e-38 131.4 14.9 5e-38 130.8 14.9 1.3 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) CDC27 PF09507.10 KFP00478.1 - 1.7 7.9 15.5 1.9 7.8 15.5 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DNA_pol_phi PF04931.13 KFP00478.1 - 2.1 6.4 21.3 2.9 5.9 21.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 KFP00478.1 - 3.3 7.4 17.9 4.5 6.9 17.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BAR_3 PF16746.5 KFP00479.1 - 2.5e-81 272.9 15.7 4.1e-81 272.2 15.7 1.4 1 0 0 1 1 1 1 BAR domain of APPL family ArfGap PF01412.18 KFP00479.1 - 4.9e-39 133.0 0.3 4.9e-39 133.0 0.3 2.6 4 0 0 4 4 4 1 Putative GTPase activating protein for Arf Ank_2 PF12796.7 KFP00479.1 - 2.9e-15 56.6 1.1 7.2e-09 36.1 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) PH PF00169.29 KFP00479.1 - 1.4e-14 54.5 0.6 1.4e-14 54.5 0.6 1.8 2 0 0 2 2 2 1 PH domain Ank_5 PF13857.6 KFP00479.1 - 1.4e-09 38.0 0.4 3e-06 27.4 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFP00479.1 - 5.4e-07 29.8 0.6 0.033 14.6 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 KFP00479.1 - 4e-06 26.8 0.1 0.03 14.9 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KFP00479.1 - 4.4e-06 27.1 0.1 0.0021 18.6 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) PH_8 PF15409.6 KFP00479.1 - 0.078 13.3 0.2 0.24 11.7 0.2 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 KFP00479.1 - 0.18 12.2 8.3 0.45 11.0 3.3 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain Glyco_transf_8 PF01501.20 KFP00480.1 - 6.4e-08 32.5 0.1 7.4e-08 32.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 PID_2 PF14719.6 KFP00481.1 - 1e-54 185.1 6.3 8.8e-36 123.5 1.7 2.1 1 1 1 2 2 2 2 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.23 KFP00481.1 - 0.012 15.7 0.1 0.058 13.4 0.0 2.0 1 1 1 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) MMR_HSR1 PF01926.23 KFP00482.1 - 5.9e-15 55.3 0.1 3.2e-13 49.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP00482.1 - 4.3e-08 33.2 0.2 0.009 15.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KFP00482.1 - 1.7e-06 27.7 0.1 0.00052 19.6 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B AIG1 PF04548.16 KFP00482.1 - 0.00095 18.6 0.0 0.0023 17.3 0.0 1.7 1 0 0 1 1 1 1 AIG1 family cobW PF02492.19 KFP00482.1 - 0.017 14.7 0.2 0.15 11.6 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 KFP00482.1 - 0.64 10.4 4.4 2.1 8.7 0.0 3.1 2 1 1 3 3 3 0 AAA ATPase domain DUF3073 PF11273.8 KFP00482.1 - 2.1 9.1 4.2 6.4 7.6 4.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3073) Dynamin_N PF00350.23 KFP00482.1 - 5 7.2 9.1 2.3 8.3 0.3 3.6 3 2 1 4 4 4 0 Dynamin family P5-ATPase PF12409.8 KFP00483.1 - 6.5e-38 129.7 0.2 1.9e-37 128.1 0.2 1.9 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KFP00483.1 - 2.1e-36 125.1 0.1 2.1e-36 125.1 0.1 2.8 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 KFP00483.1 - 2.6e-16 60.6 0.2 2.6e-10 40.9 0.1 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFP00483.1 - 7.7e-07 29.1 0.0 1.6e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFP00483.1 - 1.9e-06 27.5 0.0 4.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus FapA PF03961.13 KFP00483.1 - 0.055 12.1 0.0 0.084 11.5 0.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Dynamin_N PF00350.23 KFP00484.1 - 1.6e-38 132.4 0.2 1.6e-38 132.4 0.2 2.9 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 KFP00484.1 - 8.6e-06 25.8 0.2 0.00019 21.5 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFP00484.1 - 0.00013 21.5 0.0 0.0089 15.6 0.1 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Roc PF08477.13 KFP00484.1 - 0.0064 16.7 0.0 0.62 10.3 0.0 3.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF1593 PF07632.11 KFP00484.1 - 0.0083 15.6 0.1 0.0083 15.6 0.1 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1593) Ras PF00071.22 KFP00484.1 - 0.024 14.2 0.0 8.2 6.0 0.0 2.6 2 0 0 2 2 2 0 Ras family AAA_16 PF13191.6 KFP00484.1 - 0.026 14.9 0.1 0.81 10.0 0.0 3.0 2 0 0 2 2 2 0 AAA ATPase domain PilO PF04350.13 KFP00484.1 - 0.04 14.1 2.2 6 7.0 0.0 3.1 3 0 0 3 3 3 0 Pilus assembly protein, PilO Ephrin_rec_like PF07699.13 KFP00484.1 - 0.18 11.6 0.6 0.38 10.5 0.6 1.5 1 0 0 1 1 1 0 Putative ephrin-receptor like ImpA_N PF06812.12 KFP00484.1 - 3.3 7.8 7.8 2.6 8.2 0.0 3.5 3 0 0 3 3 3 0 ImpA, N-terminal, type VI secretion system DUF2203 PF09969.9 KFP00484.1 - 4.7 7.9 9.4 0.37 11.5 0.7 3.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) FlaC_arch PF05377.11 KFP00484.1 - 9.2 6.8 7.8 41 4.7 1.8 3.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) E1-E2_ATPase PF00122.20 KFP00485.1 - 5.1e-36 123.9 0.0 5.1e-36 123.9 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.8 KFP00485.1 - 2.9e-33 114.6 0.8 7.7e-33 113.3 0.8 1.8 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 KFP00485.1 - 5.3e-12 46.5 0.2 1.3e-06 28.9 0.4 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFP00485.1 - 8.5e-07 28.6 0.0 3.1e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KFP00485.1 - 0.00014 21.9 0.0 0.00034 20.6 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) MIP-T3 PF10243.9 KFP00485.1 - 0.15 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CH-like domain TcpE PF12648.7 KFP00485.1 - 5.5 7.6 7.7 0.71 10.4 1.7 2.5 2 0 0 2 2 2 0 TcpE family P5-ATPase PF12409.8 KFP00486.1 - 8.3e-33 113.2 2.1 4.6e-32 110.8 1.6 2.2 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KFP00486.1 - 2.4e-30 105.4 0.5 8e-30 103.7 0.0 2.2 2 1 1 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KFP00486.1 - 3.8e-16 60.0 0.6 1.4e-09 38.5 0.8 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFP00486.1 - 2.3e-07 30.4 0.1 2.9e-06 26.9 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KFP00486.1 - 2.4e-06 27.6 0.0 7e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) FtsL PF04999.13 KFP00486.1 - 0.066 13.2 0.6 0.22 11.5 0.6 1.9 1 0 0 1 1 1 0 Cell division protein FtsL DUF2620 PF10941.8 KFP00486.1 - 0.067 13.3 0.4 0.34 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF2620 LRAT PF04970.13 KFP00487.1 - 1.4e-33 115.9 0.0 1.7e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Lecithin retinol acyltransferase Calici_PP_N PF08405.11 KFP00487.1 - 0.02 13.7 0.1 0.031 13.1 0.1 1.7 1 1 0 1 1 1 0 Viral polyprotein N-terminal Herpes_UL36 PF03586.13 KFP00487.1 - 0.059 12.7 0.0 0.076 12.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein Mab-21 PF03281.14 KFP00488.1 - 2.2e-33 115.8 0.2 2.9e-33 115.4 0.2 1.2 1 0 0 1 1 1 1 Mab-21 protein PIN_11 PF18479.1 KFP00488.1 - 0.1 12.8 0.1 3.8 7.7 0.0 3.0 3 0 0 3 3 3 0 PIN like domain FGF PF00167.18 KFP00489.1 - 1.8e-39 134.7 0.0 2.5e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Fibroblast growth factor CDtoxinA PF03498.14 KFP00489.1 - 0.18 11.4 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain CCDC50_N PF15295.6 KFP00491.1 - 4.1e-46 156.2 48.0 8.8e-42 142.2 27.1 2.6 3 0 0 3 3 3 2 Coiled-coil domain-containing protein 50 N-terminus Urotensin_II PF02083.15 KFP00492.1 - 0.00013 21.4 4.8 0.00022 20.7 4.8 1.4 1 0 0 1 1 1 1 Urotensin II Dynactin_p22 PF07426.11 KFP00492.1 - 0.0091 15.9 3.2 0.89 9.4 0.3 2.1 2 0 0 2 2 2 2 Dynactin subunit p22 Musclin PF11037.8 KFP00493.1 - 1.1e-46 158.1 0.2 1.1e-46 158.0 0.2 1.0 1 0 0 1 1 1 1 Insulin-resistance promoting peptide in skeletal muscle ANP PF00212.18 KFP00493.1 - 0.00045 20.3 0.3 1.4 9.2 0.0 2.4 2 0 0 2 2 2 2 Atrial natriuretic peptide RBD-FIP PF09457.10 KFP00494.1 - 0.00061 19.7 2.9 0.0012 18.7 2.9 1.4 1 0 0 1 1 1 1 FIP domain HSCB_C PF07743.13 KFP00494.1 - 0.045 14.3 1.3 0.065 13.7 1.3 1.3 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain TIR PF01582.20 KFP00495.1 - 2.7e-28 98.9 0.0 4.7e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 TIR domain Ig_6 PF18452.1 KFP00495.1 - 3.4e-21 74.5 2.0 1.7e-20 72.3 0.1 2.7 3 0 0 3 3 3 1 Immunoglobulin domain Ig_3 PF13927.6 KFP00495.1 - 4e-17 62.6 0.5 2.7e-09 37.5 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFP00495.1 - 4.4e-13 49.2 1.4 6.8e-07 29.4 0.2 3.6 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KFP00495.1 - 1e-11 45.0 0.4 0.0027 18.0 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain TIR_2 PF13676.6 KFP00495.1 - 3.4e-10 40.6 0.0 6.5e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 TIR domain I-set PF07679.16 KFP00495.1 - 1.6e-09 37.7 0.1 0.00086 19.3 0.1 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain Izumo-Ig PF16706.5 KFP00495.1 - 0.057 13.5 0.5 7.4 6.7 0.0 3.5 3 1 0 3 3 3 0 Izumo-like Immunoglobulin domain TMEM52 PF14979.6 KFP00496.1 - 6e-06 26.3 14.5 8.9e-05 22.4 14.5 2.0 1 1 0 1 1 1 1 Transmembrane 52 Hum_adeno_E3A PF05393.11 KFP00496.1 - 0.0019 18.1 0.9 0.0028 17.6 0.9 1.3 1 0 0 1 1 1 1 Human adenovirus early E3A glycoprotein TMIE PF16038.5 KFP00496.1 - 2.3 8.1 6.0 3.3 7.6 6.0 1.2 1 0 0 1 1 1 0 TMIE protein PMP22_Claudin PF00822.20 KFP00497.1 - 1.6e-18 67.1 10.0 2e-18 66.8 10.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP00497.1 - 3.5e-06 26.9 13.6 8.2e-06 25.7 13.6 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DuoxA PF10204.9 KFP00497.1 - 0.22 10.5 7.7 0.019 14.0 3.4 1.5 2 0 0 2 2 2 0 Dual oxidase maturation factor Phage_holin_3_6 PF07332.11 KFP00497.1 - 8 6.5 11.3 2.6 8.1 2.0 2.9 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III PMP22_Claudin PF00822.20 KFP00498.1 - 7.6e-49 165.8 10.0 8.8e-49 165.6 10.0 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP00498.1 - 1.7e-10 41.0 12.1 9.7e-10 38.5 11.5 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction CD20 PF04103.15 KFP00498.1 - 0.0048 17.0 1.1 0.0048 17.0 1.1 2.7 2 1 1 3 3 3 1 CD20-like family DUF4134 PF13572.6 KFP00498.1 - 0.0097 16.2 2.0 0.0097 16.2 2.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4134) DUF981 PF06168.11 KFP00498.1 - 0.015 15.2 5.3 0.2 11.5 5.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF981) DUF2157 PF09925.9 KFP00498.1 - 0.35 10.7 0.1 0.35 10.7 0.1 2.9 4 0 0 4 4 4 0 Predicted membrane protein (DUF2157) DUF998 PF06197.13 KFP00498.1 - 0.42 10.2 10.8 0.028 14.0 4.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF998) DUF4131 PF13567.6 KFP00498.1 - 0.6 9.7 4.2 1.1 8.9 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) SUR7 PF06687.12 KFP00498.1 - 0.67 9.5 7.0 0.19 11.4 3.1 1.9 1 1 1 2 2 2 0 SUR7/PalI family DUF898 PF05987.13 KFP00498.1 - 0.7 8.9 9.2 0.097 11.7 2.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF898) Gram_pos_anchor PF00746.21 KFP00498.1 - 2.1 8.4 6.6 28 4.8 0.4 3.6 3 0 0 3 3 3 0 LPXTG cell wall anchor motif DUF4282 PF14110.6 KFP00498.1 - 2.4 8.9 7.6 2.4 8.9 2.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) DUF1218 PF06749.12 KFP00498.1 - 3.9 8.1 8.1 1.6 9.3 1.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) 2OG-FeII_Oxy_3 PF13640.6 KFP00499.1 - 3.8e-11 43.7 0.0 1.9e-10 41.5 0.0 2.2 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KFP00499.1 - 2.4e-09 37.6 0.0 1.8e-08 34.8 0.0 2.4 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily Fis1_TPR_C PF14853.6 KFP00499.1 - 0.0026 17.8 1.2 0.01 15.9 0.1 2.4 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 KFP00499.1 - 0.01 15.9 7.2 1.5 9.1 0.5 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFP00499.1 - 0.011 15.5 8.1 0.25 11.2 0.5 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat YfiO PF13525.6 KFP00499.1 - 0.012 15.4 5.6 0.15 11.8 0.1 2.9 3 0 0 3 3 3 0 Outer membrane lipoprotein Oxygenase-NA PF09859.9 KFP00499.1 - 0.036 13.6 0.0 0.51 9.8 0.0 2.3 1 1 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA TPR_14 PF13428.6 KFP00499.1 - 0.061 14.2 0.8 1.5 9.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP00499.1 - 0.085 12.9 3.7 11 6.3 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat P53 PF00870.18 KFP00500.1 - 2.8e-65 219.7 1.2 2.9e-65 219.7 0.0 1.6 2 0 0 2 2 2 1 P53 DNA-binding domain P53_tetramer PF07710.11 KFP00500.1 - 5.4e-19 67.2 0.4 1.9e-18 65.5 0.2 2.0 2 0 0 2 2 2 1 P53 tetramerisation motif SAM_2 PF07647.17 KFP00500.1 - 4.4e-10 39.5 0.0 8.5e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFP00500.1 - 0.024 15.1 0.0 0.065 13.7 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF2357 PF09823.9 KFP00500.1 - 0.17 11.1 2.4 0.42 9.8 2.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) LIM PF00412.22 KFP00501.1 - 1.9e-36 124.1 27.7 3.5e-14 52.8 6.4 3.1 3 0 0 3 3 3 3 LIM domain Mut7-C PF01927.16 KFP00501.1 - 0.05 13.7 0.8 0.05 13.7 0.8 3.4 2 1 1 3 3 3 0 Mut7-C RNAse domain zf-dskA_traR PF01258.17 KFP00501.1 - 1.2 9.1 0.1 1.2 9.1 0.1 6.4 8 1 0 8 8 8 0 Prokaryotic dksA/traR C4-type zinc finger BTB PF00651.31 KFP00502.1 - 4.1e-27 94.6 0.3 6.9e-27 93.9 0.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFP00502.1 - 6.4e-23 80.1 53.7 8.3e-07 29.2 0.5 7.1 8 0 0 8 8 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFP00502.1 - 6.7e-18 64.1 58.3 3.7e-05 23.9 0.3 7.5 7 0 0 7 7 6 6 Zinc finger, C2H2 type zf-met PF12874.7 KFP00502.1 - 2.7e-11 43.4 30.9 0.0081 16.5 0.1 7.1 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFP00502.1 - 8.5e-11 41.8 56.5 0.012 16.4 1.1 7.7 7 0 0 7 7 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP00502.1 - 2.7e-05 24.3 19.9 0.41 11.0 2.0 6.3 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFP00502.1 - 0.021 14.6 0.9 0.021 14.6 0.9 7.3 6 2 0 6 6 6 0 C2H2-type zinc-finger domain Zn-ribbon_8 PF09723.10 KFP00502.1 - 0.032 14.3 1.3 0.032 14.3 1.3 5.7 4 3 3 7 7 7 0 Zinc ribbon domain DUF3342 PF11822.8 KFP00502.1 - 0.033 14.4 0.4 0.074 13.2 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) zf-C2H2_6 PF13912.6 KFP00502.1 - 0.039 14.0 0.1 0.039 14.0 0.1 6.5 7 0 0 7 7 6 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFP00502.1 - 0.081 12.7 0.3 0.081 12.7 0.3 6.4 7 0 0 7 7 6 0 zinc-finger C2H2-type zf-C2HE PF16278.5 KFP00502.1 - 0.085 13.3 38.1 0.2 12.2 0.3 6.9 1 1 6 7 7 7 0 C2HE / C2H2 / C2HC zinc-binding finger DUF3268 PF11672.8 KFP00502.1 - 1 9.7 14.5 1 9.7 0.3 4.0 3 1 1 4 4 4 0 zinc-finger-containing domain GAGA PF09237.11 KFP00502.1 - 1.2 9.0 17.2 7.2 6.5 0.0 5.2 1 1 4 5 5 5 0 GAGA factor Somatostatin PF03002.15 KFP00503.1 - 9.7e-13 47.8 8.4 1.3e-12 47.3 8.4 1.2 1 0 0 1 1 1 1 Somatostatin/Cortistatin family Trypsin PF00089.26 KFP00504.1 - 7.3e-57 192.7 0.0 1.1e-56 192.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 KFP00504.1 - 2.8e-50 169.2 1.0 6.1e-29 100.6 0.1 2.6 2 0 0 2 2 2 2 CUB domain Sushi PF00084.20 KFP00504.1 - 7.5e-16 58.5 18.7 6.7e-09 36.2 0.2 4.7 5 0 0 5 5 5 2 Sushi repeat (SCR repeat) FXa_inhibition PF14670.6 KFP00504.1 - 1.5e-08 34.7 10.8 5.7e-08 32.9 8.4 3.0 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site CUB_2 PF02408.20 KFP00504.1 - 8.6e-06 25.5 0.2 0.018 14.8 0.0 2.8 3 0 0 3 3 3 2 CUB-like domain EGF_CA PF07645.15 KFP00504.1 - 2.8e-05 24.2 7.9 2.8e-05 24.2 7.9 2.5 3 0 0 3 3 3 1 Calcium-binding EGF domain Trypsin_2 PF13365.6 KFP00504.1 - 6.3e-05 23.9 0.1 0.00012 23.0 0.1 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain cEGF PF12662.7 KFP00504.1 - 0.00018 21.4 5.5 0.0042 17.0 3.9 3.2 2 0 0 2 2 2 1 Complement Clr-like EGF-like DUF1986 PF09342.11 KFP00504.1 - 0.021 15.2 0.0 0.047 14.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) HRM PF02793.22 KFP00504.1 - 0.035 14.4 2.0 8.8 6.7 0.2 2.7 2 0 0 2 2 2 0 Hormone receptor domain DUF2244 PF10003.9 KFP00504.1 - 0.12 12.1 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) V-set PF07686.17 KFP00505.1 - 4.4e-11 42.9 0.1 7.5e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP00505.1 - 1.1e-05 25.9 0.1 2.6e-05 24.7 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP00505.1 - 0.00021 21.4 0.3 0.00051 20.2 0.3 1.6 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP00505.1 - 0.00057 19.9 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP00505.1 - 0.0057 17.0 0.9 0.015 15.7 0.4 1.9 2 1 0 2 2 2 1 Immunoglobulin domain DUF872 PF05915.12 KFP00505.1 - 0.073 13.2 0.1 0.16 12.2 0.0 1.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Tctex-1 PF03645.13 KFP00506.1 - 7.2e-13 48.7 0.0 8.2e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family Trans_coact PF16805.5 KFP00506.1 - 0.086 13.0 0.1 2.3 8.4 0.0 2.1 2 0 0 2 2 2 0 Phage late-transcription coactivator CTP_transf_like PF01467.26 KFP00507.1 - 5.7e-32 110.9 0.5 1.2e-31 109.9 0.0 1.7 2 0 0 2 2 2 1 Cytidylyltransferase-like DUF1664 PF07889.12 KFP00507.1 - 0.055 13.5 0.6 0.092 12.8 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) KH_5 PF13184.6 KFP00507.1 - 0.058 13.5 0.5 0.16 12.0 0.5 1.7 1 0 0 1 1 1 0 NusA-like KH domain YtxH PF12732.7 KFP00507.1 - 0.24 11.9 2.5 0.46 11.1 2.5 1.4 1 0 0 1 1 1 0 YtxH-like protein AKNA PF12443.8 KFP00507.1 - 0.42 11.3 2.8 0.54 11.0 0.8 2.1 2 0 0 2 2 2 0 AT-hook-containing transcription factor DUF3678 PF12435.8 KFP00507.1 - 2.4 7.6 6.2 0.81 9.1 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Peptidase_M28 PF04389.17 KFP00508.1 - 1.4e-14 54.3 0.0 2.6e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.15 KFP00508.1 - 9.2e-09 35.5 0.3 2.3e-08 34.2 0.1 1.8 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain PA PF02225.22 KFP00508.1 - 2.8e-07 30.5 0.2 1e-06 28.6 0.2 2.0 2 0 0 2 2 2 1 PA domain NADH_oxidored PF08040.11 KFP00508.1 - 0.42 10.4 1.8 19 5.0 0.2 2.9 3 0 0 3 3 3 0 MNLL subunit NIDO PF06119.14 KFP00509.1 - 1e-11 45.6 0.4 3.9e-11 43.7 0.1 1.8 2 0 0 2 2 2 1 Nidogen-like NIDO PF06119.14 KFP00511.1 - 4.6e-11 43.5 0.5 8.8e-11 42.6 0.5 1.5 1 0 0 1 1 1 1 Nidogen-like DNA_photolyase PF00875.18 KFP00512.1 - 1.5e-20 73.8 0.0 2.8e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase FAD_binding_7 PF03441.14 KFP00512.1 - 0.032 13.7 0.9 0.065 12.7 0.9 1.6 1 1 0 1 1 1 0 FAD binding domain of DNA photolyase zf-RING_9 PF13901.6 KFP00513.1 - 6.5e-69 232.0 16.1 6.5e-69 232.0 16.1 2.3 2 0 0 2 2 2 1 Putative zinc-RING and/or ribbon RUN PF02759.19 KFP00513.1 - 9.3e-09 35.3 0.3 2.2e-08 34.1 0.3 1.6 1 0 0 1 1 1 1 RUN domain FYTT PF07078.11 KFP00514.1 - 3.7e-132 440.4 21.0 4.5e-132 440.1 21.0 1.0 1 0 0 1 1 1 1 Forty-two-three protein RVT_1 PF00078.27 KFP00515.1 - 0.0055 16.3 0.0 0.0087 15.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_8 PF13855.6 KFP00516.1 - 1.5e-23 82.3 11.0 2.1e-08 33.8 1.5 3.4 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFP00516.1 - 2.5e-16 59.5 19.5 0.00013 22.3 3.1 5.3 2 1 2 5 5 5 5 Leucine Rich repeats (2 copies) CH PF00307.31 KFP00516.1 - 3.6e-10 40.0 0.0 7.4e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain LRR_1 PF00560.33 KFP00516.1 - 0.0032 17.8 22.5 30 5.7 0.7 8.5 9 0 0 9 9 9 0 Leucine Rich Repeat LRR_6 PF13516.6 KFP00516.1 - 0.0091 16.0 16.5 0.62 10.3 0.0 6.3 6 0 0 6 6 6 2 Leucine Rich repeat CAMSAP_CH PF11971.8 KFP00516.1 - 0.017 14.9 0.0 0.055 13.3 0.0 1.8 1 0 0 1 1 1 0 CAMSAP CH domain LRR_9 PF14580.6 KFP00516.1 - 2.3 7.7 6.1 4.7 6.7 2.7 2.8 1 1 2 3 3 3 0 Leucine-rich repeat IQ PF00612.27 KFP00517.1 - 4.1e-05 23.0 0.3 0.00011 21.7 0.3 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif UCR_14kD PF02271.16 KFP00517.1 - 0.025 14.5 0.4 0.025 14.5 0.4 3.0 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase complex 14kD subunit FAM117 PF15388.6 KFP00517.1 - 2.3 7.6 13.0 1.2 8.5 10.6 1.7 1 1 0 1 1 1 0 Protein Family FAM117 ApoO PF09769.9 KFP00517.1 - 6.3 6.8 11.3 26 4.8 0.1 3.6 2 2 1 4 4 4 0 Apolipoprotein O Ribosomal_L35Ae PF01247.18 KFP00518.1 - 3.2e-46 155.4 0.5 3.5e-46 155.3 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae DUF2080 PF09853.9 KFP00518.1 - 0.027 14.2 0.7 0.1 12.3 0.0 2.3 2 1 1 3 3 3 0 Putative transposon-encoded protein (DUF2080) RimM PF01782.18 KFP00518.1 - 0.085 13.1 0.0 0.97 9.7 0.0 2.0 2 0 0 2 2 2 0 RimM N-terminal domain RPN2_C PF18004.1 KFP00519.1 - 1.6e-49 167.9 10.9 3.8e-49 166.7 10.9 1.6 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KFP00519.1 - 1.3e-42 142.1 19.5 5e-09 36.1 0.0 7.9 7 0 0 7 7 7 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KFP00519.1 - 2.3e-21 76.0 0.4 1.3e-14 54.4 0.0 5.5 4 1 1 6 6 6 2 HEAT repeats RPN1_RPN2_N PF17781.1 KFP00519.1 - 1.4e-08 34.5 0.2 3.9e-08 33.1 0.2 1.8 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain HEAT PF02985.22 KFP00519.1 - 7.2e-06 25.8 1.0 1.3 9.5 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 KFP00519.1 - 0.00047 20.6 1.5 0.52 10.9 0.0 5.0 5 1 2 7 7 6 2 HEAT-like repeat HEAT_PBS PF03130.16 KFP00519.1 - 0.0018 18.8 1.6 6.7 7.7 0.0 4.6 4 0 0 4 4 3 1 PBS lyase HEAT-like repeat PA26 PF04636.13 KFP00519.1 - 0.067 12.1 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Tim54 PF11711.8 KFP00519.1 - 0.29 9.9 7.7 0.47 9.2 7.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Vfa1 PF08432.10 KFP00519.1 - 0.63 10.3 12.5 3.5 7.9 12.0 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 NARP1 PF12569.8 KFP00519.1 - 4.5 6.1 11.4 10 4.9 11.4 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1764 PF08576.10 KFP00519.1 - 4.5 8.2 14.3 11 7.0 14.3 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) 7tm_1 PF00001.21 KFP00520.1 - 3.5e-65 220.0 13.8 4.8e-65 219.5 13.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP00520.1 - 4e-11 42.8 16.2 1.3e-10 41.2 16.2 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP00520.1 - 7.7e-08 32.4 4.1 7.7e-08 32.4 4.1 2.2 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP00520.1 - 1.6e-05 24.6 12.6 1.6e-05 24.6 12.6 2.4 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2385 PF09539.10 KFP00520.1 - 0.041 14.4 0.0 0.085 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) zf-LITAF-like PF10601.9 KFP00520.1 - 0.45 10.8 2.7 1.4 9.3 1.0 2.8 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain DUF1385 PF07136.11 KFP00520.1 - 2.2 7.5 8.2 0.069 12.4 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1385) CENP-B_dimeris PF09026.10 KFP00521.1 - 0.019 15.3 3.5 0.031 14.7 1.8 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RRM_1 PF00076.22 KFP00522.1 - 5.4e-69 228.0 7.4 2.6e-17 62.4 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 KFP00522.1 - 4.4e-06 26.6 1.0 0.13 12.0 0.1 4.3 4 0 0 4 4 4 2 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 KFP00522.1 - 1.6e-05 24.7 0.2 0.02 14.7 0.0 3.5 3 0 0 3 3 3 1 Occluded RNA-recognition motif BUD22 PF09073.10 KFP00522.1 - 7.6e-05 22.2 48.0 7.6e-05 22.2 48.0 3.1 3 0 0 3 3 3 1 BUD22 RRM_7 PF16367.5 KFP00522.1 - 0.00024 21.2 0.1 8.1 6.6 0.0 4.2 4 0 0 4 4 4 1 RNA recognition motif Limkain-b1 PF11608.8 KFP00522.1 - 0.0012 18.9 2.1 1.8 8.7 0.0 4.3 4 0 0 4 4 4 1 Limkain b1 DbpA PF03880.15 KFP00522.1 - 0.0022 18.0 0.4 0.24 11.4 0.0 3.5 4 0 0 4 4 4 1 DbpA RNA binding domain Nup35_RRM_2 PF14605.6 KFP00522.1 - 0.01 15.8 0.2 2.4 8.2 0.1 3.6 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KFP00522.1 - 0.012 15.3 0.2 8.4 6.0 0.0 3.4 1 1 1 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 KFP00522.1 - 0.018 14.6 0.1 4.6 7.0 0.0 3.3 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated DUF5635 PF18685.1 KFP00522.1 - 0.025 14.5 0.3 3.5 7.6 0.0 3.2 4 0 0 4 4 4 0 Family of unknown function (DUF5635) CENP-B_dimeris PF09026.10 KFP00522.1 - 8.6 6.8 78.5 0.042 14.2 11.3 3.4 2 1 1 3 3 3 0 Centromere protein B dimerisation domain GMP_PDE_delta PF05351.11 KFP00523.1 - 6.1e-44 149.9 0.1 1e-43 149.1 0.1 1.3 1 1 0 1 1 1 1 GMP-PDE, delta subunit CSN7a_helixI PF18392.1 KFP00524.1 - 1e-22 79.8 2.5 1.9e-22 78.9 2.5 1.5 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain PCI PF01399.27 KFP00524.1 - 1.8e-09 38.0 3.8 3.5e-09 37.1 0.3 2.2 2 0 0 2 2 2 1 PCI domain Band_3_cyto PF07565.13 KFP00524.1 - 0.021 14.6 5.1 0.038 13.8 4.9 1.4 1 1 0 1 1 1 0 Band 3 cytoplasmic domain OB_Dis3 PF17849.1 KFP00525.1 - 3.7e-26 91.0 0.0 5.6e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 KFP00525.1 - 0.00096 19.3 0.0 0.0033 17.6 0.0 1.9 2 0 0 2 2 2 1 Cold shock domain RNB PF00773.19 KFP00526.1 - 1.5e-17 63.9 0.1 1.9e-17 63.6 0.1 1.2 1 0 0 1 1 1 1 RNB domain Alk_phosphatase PF00245.20 KFP00527.1 - 3.9e-158 526.8 0.7 4.5e-158 526.6 0.7 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 KFP00527.1 - 0.0027 17.1 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Alk_phosphatase PF00245.20 KFP00528.1 - 2.5e-165 550.5 0.0 2.8e-165 550.3 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 KFP00528.1 - 0.03 13.7 0.0 0.057 12.8 0.0 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily Peptidase_M13_N PF05649.13 KFP00529.1 - 5.8e-106 355.4 0.0 7.6e-106 355.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFP00529.1 - 9.1e-70 234.4 0.3 1.5e-69 233.7 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M13 AA_permease PF00324.21 KFP00530.1 - 8.1e-22 77.5 6.1 9.8e-22 77.2 6.1 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KFP00530.1 - 2e-19 69.9 0.1 5.5e-12 45.4 0.0 3.2 3 0 0 3 3 3 3 Solute carrier family 12 Trypsin PF00089.26 KFP00531.1 - 1.6e-43 149.1 0.0 1.7e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFP00531.1 - 0.047 14.6 0.2 0.095 13.6 0.2 1.5 1 1 0 1 1 1 0 Trypsin-like peptidase domain Neur_chan_memb PF02932.16 KFP00532.1 - 8.2e-72 242.1 0.2 1.1e-71 241.7 0.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFP00532.1 - 4.1e-71 238.9 4.3 6.1e-71 238.3 4.3 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain IF4E PF01652.18 KFP00533.1 - 2.7e-60 202.8 0.1 3.3e-60 202.5 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E p450 PF00067.22 KFP00534.1 - 7.2e-120 400.8 0.0 8.2e-120 400.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2124 PF09897.9 KFP00534.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2124) p450 PF00067.22 KFP00535.1 - 3.5e-120 401.9 0.0 4e-120 401.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFP00536.1 - 9.9e-125 416.9 0.6 1.1e-124 416.7 0.6 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mlp PF03304.13 KFP00536.1 - 0.041 14.1 0.1 0.082 13.1 0.1 1.4 1 0 0 1 1 1 0 Mlp lipoprotein family p450 PF00067.22 KFP00537.1 - 7.8e-122 407.3 0.0 8.8e-122 407.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFP00538.1 - 1.2e-121 406.8 0.8 1.3e-121 406.6 0.8 1.0 1 0 0 1 1 1 1 Cytochrome P450 MCM6_C PF18263.1 KFP00538.1 - 0.046 14.0 0.0 0.092 13.0 0.0 1.4 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain NPH3 PF03000.14 KFP00538.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 NPH3 family Peptidase_C2 PF00648.21 KFP00539.1 - 4.3e-81 272.2 0.0 6.2e-81 271.7 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KFP00539.1 - 9.3e-45 152.4 0.0 8.7e-23 81.1 0.0 2.6 2 1 0 2 2 2 2 Calpain large subunit, domain III Peptidase_M1 PF01433.20 KFP00540.1 - 5.5e-40 137.3 0.0 1.1e-39 136.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KFP00540.1 - 2.8e-28 98.3 0.1 5.7e-28 97.3 0.1 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KFP00540.1 - 1.5e-10 41.6 0.4 2.8e-10 40.7 0.2 1.6 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF2268 PF10026.9 KFP00540.1 - 0.0081 15.7 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Predicted Zn-dependent protease (DUF2268) W2 PF02020.18 KFP00541.1 - 7.5e-19 67.7 2.2 7.5e-19 67.7 2.2 2.9 3 1 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 KFP00541.1 - 1.6e-13 49.8 5.4 0.00041 20.0 0.7 3.6 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 KFP00541.1 - 0.0069 14.6 0.3 0.012 13.8 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 KFP00541.1 - 0.01 15.5 7.4 0.94 9.3 4.9 3.8 2 1 2 4 4 4 0 Hexapeptide repeat of succinyl-transferase SPG4 PF17325.2 KFP00541.1 - 0.06 14.4 0.9 0.15 13.1 0.9 1.6 1 0 0 1 1 1 0 Stationary phase protein 4 VIR_N PF15912.5 KFP00541.1 - 0.062 12.9 3.0 0.1 12.2 3.0 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal DUF4007 PF13182.6 KFP00541.1 - 0.063 12.4 0.5 1.3 8.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4007) Fucokinase PF07959.12 KFP00541.1 - 0.12 11.3 1.0 0.27 10.1 1.0 1.6 1 1 0 1 1 1 0 L-fucokinase Dsh_C PF12316.8 KFP00542.1 - 6.3e-79 265.2 31.8 6.3e-79 265.2 31.8 2.6 2 1 0 2 2 2 1 Segment polarity protein dishevelled (Dsh) C terminal Dishevelled PF02377.15 KFP00542.1 - 6.4e-67 225.1 23.1 6.4e-67 225.1 23.1 2.6 3 0 0 3 3 3 1 Dishevelled specific domain PDZ PF00595.24 KFP00542.1 - 8.7e-19 67.7 0.3 1.5e-18 66.9 0.3 1.4 1 0 0 1 1 1 1 PDZ domain DEP PF00610.21 KFP00542.1 - 3.2e-17 62.3 0.0 7.1e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DIX PF00778.17 KFP00542.1 - 7.8e-06 25.6 0.1 3.3e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 DIX domain PDZ_6 PF17820.1 KFP00542.1 - 4.4e-05 23.2 0.0 8.4e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP00542.1 - 0.006 16.9 0.1 0.011 16.0 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Shufflon_N PF04917.12 KFP00542.1 - 0.029 13.8 0.1 0.049 13.1 0.1 1.3 1 0 0 1 1 1 0 Bacterial shufflon protein, N-terminal constant region Adap_comp_sub PF00928.21 KFP00543.1 - 7.3e-82 274.7 0.1 9.4e-82 274.3 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFP00543.1 - 7.1e-06 26.0 0.5 1.2e-05 25.3 0.5 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KFP00543.1 - 0.022 14.2 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain ABC_tran PF00005.27 KFP00544.1 - 3e-43 147.6 0.4 2.3e-20 73.5 0.0 3.1 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KFP00544.1 - 1e-23 83.2 4.5 1e-23 83.2 4.5 2.9 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 KFP00544.1 - 3.6e-15 56.6 2.9 0.0014 18.5 0.0 5.0 5 1 0 6 6 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFP00544.1 - 8.6e-14 51.5 0.1 4.9e-05 22.9 0.0 4.1 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KFP00544.1 - 5.2e-08 33.0 0.1 0.0038 17.0 0.0 4.0 4 0 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 KFP00544.1 - 1.3e-06 28.7 1.4 0.051 13.8 0.0 4.0 3 2 0 3 3 3 2 AAA domain NACHT PF05729.12 KFP00544.1 - 1.8e-05 24.7 0.7 0.15 12.0 0.0 2.9 3 0 0 3 3 3 2 NACHT domain AAA PF00004.29 KFP00544.1 - 2.9e-05 24.5 0.8 0.41 11.1 0.1 3.6 3 2 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KFP00544.1 - 3.4e-05 23.9 0.0 0.046 13.8 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP00544.1 - 0.00014 21.9 0.0 0.2 11.5 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KFP00544.1 - 0.00014 21.5 0.1 0.055 13.2 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KFP00544.1 - 0.00022 21.7 0.1 1.2 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_24 PF13479.6 KFP00544.1 - 0.00025 20.9 0.0 1 9.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KFP00544.1 - 0.00083 19.1 0.4 1.2 8.9 0.0 3.7 3 1 0 3 3 3 1 AAA domain Dynamin_N PF00350.23 KFP00544.1 - 0.002 18.2 2.3 0.073 13.1 0.0 3.4 2 1 0 2 2 2 1 Dynamin family RNA_helicase PF00910.22 KFP00544.1 - 0.0032 17.9 0.3 0.62 10.5 0.0 2.8 3 0 0 3 3 2 1 RNA helicase NB-ARC PF00931.22 KFP00544.1 - 0.0035 16.6 0.0 0.53 9.4 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain DUF87 PF01935.17 KFP00544.1 - 0.0082 16.3 9.2 0.31 11.1 0.0 3.7 5 0 0 5 5 4 2 Helicase HerA, central domain AAA_14 PF13173.6 KFP00544.1 - 0.0088 16.1 0.4 1.9 8.5 0.0 3.5 3 1 1 4 4 4 1 AAA domain Roc PF08477.13 KFP00544.1 - 0.0098 16.1 0.0 2.1 8.6 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 KFP00544.1 - 0.01 15.2 0.0 5.1 6.3 0.0 2.4 2 0 0 2 2 2 0 Septin AAA_18 PF13238.6 KFP00544.1 - 0.012 16.1 1.2 1.6 9.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain MobB PF03205.14 KFP00544.1 - 0.014 15.3 0.1 5.7 6.8 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.6 KFP00544.1 - 0.018 15.3 0.5 2.4 8.4 0.1 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 KFP00544.1 - 0.018 15.3 0.8 15 5.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 KFP00544.1 - 0.02 14.8 0.0 9.1 6.2 0.0 2.8 2 0 0 2 2 2 0 NTPase AAA_23 PF13476.6 KFP00544.1 - 0.041 14.4 16.2 0.4 11.2 0.0 4.2 4 1 1 5 5 4 0 AAA domain Arf PF00025.21 KFP00544.1 - 0.05 13.1 0.2 1.8 8.0 0.0 2.9 3 0 0 3 3 3 0 ADP-ribosylation factor family DUF1672 PF07901.11 KFP00544.1 - 0.064 12.6 0.8 0.11 11.8 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) TsaE PF02367.17 KFP00544.1 - 0.077 13.0 0.0 12 5.9 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MeaB PF03308.16 KFP00544.1 - 0.082 11.9 0.0 2.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 KFP00544.1 - 0.1 12.1 0.3 5.2 6.6 0.0 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KFP00544.1 - 0.1 11.9 0.1 0.84 8.9 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 KFP00544.1 - 0.12 11.9 0.1 10 5.7 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KFP00544.1 - 0.12 12.5 3.3 3.3 7.9 0.0 3.1 3 1 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 KFP00544.1 - 0.13 12.0 0.1 15 5.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_13 PF13166.6 KFP00544.1 - 1.6 7.3 7.5 2.1 6.9 0.0 3.3 2 2 2 4 4 4 0 AAA domain PHD PF00628.29 KFP00545.1 - 4.4e-08 32.9 5.6 9.5e-08 31.8 5.6 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KFP00545.1 - 1.1e-07 31.3 2.6 2.3e-07 30.2 2.6 1.6 1 0 0 1 1 1 1 PHD-finger zf-RING_9 PF13901.6 KFP00545.1 - 0.49 10.3 5.8 0.7 9.8 5.8 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon C1_1 PF00130.22 KFP00545.1 - 0.66 9.9 4.3 0.17 11.8 0.9 1.8 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Peptidase_M13_N PF05649.13 KFP00547.1 - 3.4e-123 412.1 1.1 4.4e-123 411.7 1.1 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFP00547.1 - 1.7e-34 119.2 0.4 1.7e-34 119.2 0.4 1.7 2 0 0 2 2 2 1 Peptidase family M13 RPN1_RPN2_N PF17781.1 KFP00548.1 - 2.8e-116 388.2 1.4 2.8e-116 388.2 1.4 1.9 3 0 0 3 3 3 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KFP00548.1 - 2.7e-32 110.5 0.3 5.7e-32 109.5 0.3 1.6 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KFP00548.1 - 4.6e-26 89.9 25.4 1.5e-06 28.3 0.1 8.8 10 0 0 10 10 10 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KFP00548.1 - 4.1e-05 23.9 0.0 0.12 12.8 0.0 4.4 4 1 1 5 5 5 1 HEAT repeats THAP PF05485.12 KFP00548.1 - 0.031 15.2 0.6 0.066 14.1 0.6 1.4 1 0 0 1 1 1 0 THAP domain TMEM82 PF15816.5 KFP00548.1 - 0.11 11.5 0.0 0.67 8.9 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein 82 MIF4G PF02854.19 KFP00549.1 - 4.7e-68 229.0 9.3 4.7e-68 229.0 9.3 1.6 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 KFP00549.1 - 5.4e-27 94.0 0.5 2.6e-26 91.8 0.2 2.4 2 1 0 2 2 2 1 MA3 domain FAM131 PF15010.6 KFP00550.1 - 3.3e-57 194.7 10.3 4.5e-56 190.9 10.3 1.9 1 1 0 1 1 1 1 Putative cell signalling CHRD PF07452.12 KFP00551.1 - 6.4e-07 30.4 0.0 6.8e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 CHRD domain CHRD PF07452.12 KFP00552.1 - 9e-27 94.3 0.1 9.1e-13 49.2 0.1 3.1 3 0 0 3 3 3 3 CHRD domain DUF3040 PF11239.8 KFP00552.1 - 0.025 14.8 0.3 0.06 13.6 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) Amnionless PF14828.6 KFP00552.1 - 0.2 10.4 9.7 0.37 9.6 9.7 1.3 1 0 0 1 1 1 0 Amnionless VWC PF00093.18 KFP00552.1 - 0.31 11.4 7.9 0.53 10.6 7.9 1.4 1 0 0 1 1 1 0 von Willebrand factor type C domain EPO_TPO PF00758.18 KFP00553.1 - 5.6e-27 94.7 0.6 6.8e-27 94.5 0.6 1.1 1 0 0 1 1 1 1 Erythropoietin/thrombopoietin RNA_pol_Rpb8 PF03870.15 KFP00554.1 - 7.6e-53 178.4 0.1 8.5e-53 178.3 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KFP00554.1 - 5.8e-05 23.1 0.0 0.042 13.9 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G Pkinase_Tyr PF07714.17 KFP00555.1 - 4.1e-95 318.0 0.0 4.7e-95 317.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP00555.1 - 6.1e-46 156.9 0.0 7.3e-46 156.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.6 KFP00555.1 - 1.6e-13 51.3 1.0 2.7e-13 50.6 1.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Haspin_kinase PF12330.8 KFP00555.1 - 0.011 14.6 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KFP00555.1 - 0.2 10.4 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KFP00555.1 - 0.2 11.0 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_C48 PF02902.19 KFP00556.1 - 2.5e-43 148.4 2.3 5.5e-43 147.3 2.3 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DEK_C PF08766.11 KFP00556.1 - 0.019 14.8 0.0 0.047 13.6 0.0 1.7 1 0 0 1 1 1 0 DEK C terminal domain Cystatin PF00031.21 KFP00557.1 - 2.9e-17 62.7 0.0 1.6e-10 41.1 0.0 2.2 2 0 0 2 2 2 2 Cystatin domain Cystatin PF00031.21 KFP00558.1 - 2e-23 82.5 0.0 3.1e-14 53.0 0.0 2.1 2 0 0 2 2 2 2 Cystatin domain Cathelicidins PF00666.17 KFP00558.1 - 4.6e-07 30.1 0.0 3.4e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Cathelicidin Staphopain_pro PF14731.6 KFP00558.1 - 0.14 12.1 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Staphopain proregion Cystatin PF00031.21 KFP00559.1 - 4e-41 139.2 2.5 2.7e-22 78.9 0.6 2.2 2 0 0 2 2 2 2 Cystatin domain Cathelicidins PF00666.17 KFP00559.1 - 1.5e-15 57.3 3.4 3.7e-07 30.4 0.2 2.1 2 0 0 2 2 2 2 Cathelicidin SQAPI PF16845.5 KFP00559.1 - 1.3e-07 31.9 0.3 3.6e-07 30.4 0.2 1.7 2 0 0 2 2 2 1 Aspartic acid proteinase inhibitor Spp-24 PF07448.11 KFP00559.1 - 3.9e-07 30.2 1.9 0.00025 21.2 0.9 2.4 2 0 0 2 2 2 2 Secreted phosphoprotein 24 (Spp-24) cystatin-like domain Spectrin_like PF18373.1 KFP00559.1 - 0.096 12.8 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 Spectrin like domain AvrLm4-7 PF18661.1 KFP00559.1 - 1.1 10.3 8.0 13 6.9 0.6 2.6 2 1 0 2 2 2 0 Avirulence Effector AvrLm4-7 DEAD PF00270.29 KFP00560.1 - 6.4e-44 149.8 0.4 1.1e-43 149.0 0.4 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP00560.1 - 2.5e-32 111.5 0.5 8.5e-31 106.6 0.1 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP00560.1 - 3.4e-08 33.7 0.0 6e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KFP00560.1 - 6.2e-05 23.4 0.2 0.00024 21.5 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFP00560.1 - 0.0011 18.7 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFP00560.1 - 0.061 13.6 0.4 0.57 10.4 0.4 2.4 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 KFP00560.1 - 0.071 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Helicase Flavi_DEAD PF07652.14 KFP00560.1 - 0.077 13.0 0.0 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain tRNA-synt_1b PF00579.25 KFP00560.1 - 0.081 12.2 0.1 0.25 10.6 0.0 1.8 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) Rep_fac_C PF08542.11 KFP00561.1 - 3.5e-19 69.0 0.2 7.2e-19 68.0 0.2 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KFP00561.1 - 7.7e-18 65.2 0.1 3.8e-17 62.9 0.0 2.2 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KFP00561.1 - 2.8e-12 46.7 0.1 2.8e-10 40.2 0.0 2.6 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 KFP00561.1 - 4.2e-06 27.2 0.1 0.0032 17.9 0.0 2.7 2 2 1 3 3 3 1 AAA ATPase domain AAA_assoc_2 PF16193.5 KFP00561.1 - 5e-06 26.8 0.0 1.4e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain Rad17 PF03215.15 KFP00561.1 - 1.2e-05 25.4 0.0 2.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 KFP00561.1 - 2.8e-05 24.0 0.0 7.7e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFP00561.1 - 9.3e-05 22.7 0.1 0.0069 16.7 0.0 2.7 2 2 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KFP00561.1 - 0.00012 22.0 0.1 0.00033 20.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KFP00561.1 - 0.00018 20.7 0.0 0.00041 19.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KFP00561.1 - 0.00061 19.6 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KFP00561.1 - 0.001 18.5 0.0 0.064 12.6 0.0 3.1 3 1 1 4 4 4 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.13 KFP00561.1 - 0.001 18.9 1.0 0.0029 17.4 0.1 2.0 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_19 PF13245.6 KFP00561.1 - 0.0015 18.8 0.1 0.012 16.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KFP00561.1 - 0.008 15.9 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF2075 PF09848.9 KFP00561.1 - 0.013 14.8 0.0 0.069 12.4 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 KFP00561.1 - 0.019 14.7 0.0 0.65 9.7 0.0 2.3 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TIP49_C PF17856.1 KFP00561.1 - 0.019 15.1 0.1 0.064 13.4 0.1 1.9 1 0 0 1 1 1 0 TIP49 AAA-lid domain AAA_5 PF07728.14 KFP00561.1 - 0.021 14.9 0.0 0.14 12.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KFP00561.1 - 0.064 13.8 0.0 0.14 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFP00561.1 - 0.07 13.4 0.0 0.17 12.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain ResIII PF04851.15 KFP00561.1 - 0.087 12.8 0.0 0.56 10.2 0.0 2.1 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit PhoH PF02562.16 KFP00561.1 - 0.087 12.3 0.0 6.5 6.2 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein DEAD PF00270.29 KFP00561.1 - 0.09 12.5 0.0 2 8.2 0.0 2.6 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_7 PF12775.7 KFP00561.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 KFP00561.1 - 0.12 12.2 0.0 0.35 10.7 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RhoGEF PF00621.20 KFP00562.1 - 6.9e-39 134.0 5.7 6.9e-39 134.0 5.7 2.5 3 1 0 3 3 3 1 RhoGEF domain PH PF00169.29 KFP00562.1 - 6.5e-09 36.2 1.0 6.5e-09 36.2 1.0 2.7 3 0 0 3 3 3 1 PH domain CRAL_TRIO_2 PF13716.6 KFP00562.1 - 1.3e-06 28.6 0.0 4.5e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain PH_10 PF15411.6 KFP00562.1 - 1.9e-05 24.9 1.9 4.5e-05 23.7 0.5 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain Spectrin PF00435.21 KFP00562.1 - 9.9e-05 22.8 0.9 9.9e-05 22.8 0.9 4.7 3 1 2 5 5 5 2 Spectrin repeat CRAL_TRIO PF00650.20 KFP00562.1 - 0.079 12.7 0.0 0.27 11.0 0.0 1.9 1 0 0 1 1 1 0 CRAL/TRIO domain Goodbye PF17109.5 KFP00562.1 - 0.98 9.9 3.4 3.7 8.0 0.1 3.6 5 0 0 5 5 5 0 fungal STAND N-terminal Goodbye domain Galactosyl_T PF01762.21 KFP00563.1 - 1.7e-46 158.5 0.0 2.5e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 KFP00563.1 - 0.00078 19.0 0.0 0.0014 18.1 0.0 1.4 1 1 0 1 1 1 1 Fringe-like EBP50_C PF09007.11 KFP00564.1 - 0.94 10.5 7.4 0.17 12.8 3.4 1.8 1 1 1 2 2 2 0 EBP50, C-terminal Lamp PF01299.17 KFP00565.1 - 2.7e-23 82.5 1.4 3.4e-23 82.1 1.4 1.1 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) CPSase_L_D2 PF02786.17 KFP00566.1 - 1.9e-77 259.5 0.1 3.5e-77 258.7 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KFP00566.1 - 1.6e-48 163.9 1.0 3.9e-47 159.3 0.2 2.5 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KFP00566.1 - 4.7e-36 123.2 0.0 2.5e-35 120.9 0.0 2.2 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KFP00566.1 - 2.2e-16 59.4 0.4 8.7e-16 57.5 0.4 2.1 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KFP00566.1 - 3.7e-14 52.8 0.1 1.4e-13 50.9 0.1 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFP00566.1 - 5.7e-10 39.0 0.2 1.4e-09 37.7 0.2 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KFP00566.1 - 2.7e-06 27.1 0.0 1.2e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KFP00566.1 - 1e-05 25.3 0.1 0.004 17.0 0.0 2.8 3 0 0 3 3 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 KFP00566.1 - 3.7e-05 24.4 0.0 0.43 11.3 0.0 2.9 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.14 KFP00566.1 - 6e-05 23.1 0.1 0.00011 22.2 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 KFP00566.1 - 0.00018 20.9 0.3 0.41 9.9 0.0 3.2 3 0 0 3 3 3 1 Sugar-transfer associated ATP-grasp HlyD_D23 PF16576.5 KFP00566.1 - 0.00023 20.5 0.1 0.19 10.9 0.0 2.5 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion GARS_A PF01071.19 KFP00566.1 - 0.00041 20.2 0.0 0.00076 19.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RnfC_N PF13375.6 KFP00566.1 - 0.012 15.5 0.2 0.041 13.8 0.1 1.9 2 0 0 2 2 1 0 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.9 KFP00566.1 - 0.041 13.8 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) ATP-grasp_4 PF13535.6 KFP00566.1 - 0.042 13.4 0.1 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 ATP-grasp domain Ntox43 PF15537.6 KFP00566.1 - 0.042 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial toxin 43 NQRA PF05896.11 KFP00566.1 - 0.058 12.8 0.2 0.12 11.8 0.2 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Cullin_binding PF03556.15 KFP00567.1 - 1.4e-37 128.8 0.9 1.4e-37 128.8 0.9 2.1 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.6 KFP00567.1 - 1.1e-09 38.0 3.0 1.3e-09 37.7 0.1 2.7 3 0 0 3 3 3 1 UBA-like domain TAP_C PF03943.13 KFP00567.1 - 0.0039 16.8 0.8 0.024 14.3 0.2 2.6 3 0 0 3 3 3 1 TAP C-terminal domain PhoLip_ATPase_C PF16212.5 KFP00568.1 - 1.7e-77 260.6 36.9 1.7e-77 260.6 36.9 2.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFP00568.1 - 1.5e-22 79.0 1.8 9.5e-22 76.5 1.8 2.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFP00568.1 - 2.5e-13 50.8 0.6 1.4e-07 32.0 0.5 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFP00568.1 - 7.2e-10 38.8 0.0 4.6e-09 36.2 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFP00568.1 - 1.9e-09 37.3 0.4 1.9e-09 37.3 0.4 3.2 2 2 2 4 4 4 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFP00568.1 - 0.00019 21.3 0.0 0.0073 16.1 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase U3_assoc_6 PF08640.11 KFP00568.1 - 0.024 14.7 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 HAD PF12710.7 KFP00568.1 - 0.11 12.9 0.1 23 5.3 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase NPR3 PF03666.13 KFP00569.1 - 4.7 5.9 10.3 4.8 5.9 10.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SOXp PF12336.8 KFP00570.1 - 2.5e-38 131.0 5.5 2.5e-38 131.0 5.5 2.5 4 0 0 4 4 4 1 SOX transcription factor HMG_box PF00505.19 KFP00570.1 - 5.7e-28 97.1 3.4 9.4e-28 96.4 3.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP00570.1 - 6.4e-12 45.9 1.9 1.2e-11 45.1 1.9 1.4 1 0 0 1 1 1 1 HMG-box domain Tetraspanin PF00335.20 KFP00571.1 - 3.3e-32 112.0 0.9 3.6e-32 111.9 0.9 1.0 1 0 0 1 1 1 1 Tetraspanin family SUR7 PF06687.12 KFP00571.1 - 0.0078 15.9 2.7 0.012 15.3 2.7 1.2 1 0 0 1 1 1 1 SUR7/PalI family MULE PF10551.9 KFP00571.1 - 0.031 14.7 0.0 0.063 13.7 0.0 1.4 1 0 0 1 1 1 0 MULE transposase domain FtsX PF02687.21 KFP00571.1 - 0.035 14.6 7.8 0.28 11.7 0.3 2.2 1 1 1 2 2 2 0 FtsX-like permease family Sigma_reg_N PF13800.6 KFP00571.1 - 0.039 14.3 1.2 7.9 6.8 0.1 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF1461 PF07314.11 KFP00571.1 - 0.04 13.8 1.0 0.92 9.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) Pilin_N PF07790.11 KFP00571.1 - 0.13 13.2 0.0 0.13 13.2 0.0 1.9 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal DUF2371 PF10177.9 KFP00571.1 - 0.27 11.4 0.7 0.5 10.5 0.2 1.6 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2371) DUF2207 PF09972.9 KFP00571.1 - 0.52 9.0 2.3 0.63 8.7 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3139 PF11337.8 KFP00571.1 - 8 7.2 6.4 2.5 8.8 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3139) Ribosom_S12_S23 PF00164.25 KFP00572.1 - 5.7e-27 93.6 0.6 6.6e-27 93.4 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Pkinase PF00069.25 KFP00573.1 - 7.7e-63 212.3 0.0 8.6e-63 212.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP00573.1 - 3e-40 138.1 0.0 3.5e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP00573.1 - 9.7e-08 31.7 0.0 1.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP00573.1 - 5.9e-05 22.0 0.0 8.3e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP00573.1 - 0.0056 16.6 0.2 0.23 11.3 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KFP00573.1 - 0.016 14.6 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family KIND PF16474.5 KFP00573.1 - 0.042 13.8 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Haspin_kinase PF12330.8 KFP00573.1 - 0.094 11.6 0.2 0.12 11.2 0.2 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Rad1 PF02144.16 KFP00574.1 - 4.7e-67 225.9 1.2 5.4e-67 225.7 1.2 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Brix PF04427.18 KFP00575.1 - 2.1e-41 142.2 1.5 2.1e-41 142.2 0.5 1.5 2 0 0 2 2 2 1 Brix domain zf-C2H2_jaz PF12171.8 KFP00576.1 - 9.6e-11 41.7 7.9 6.9e-10 39.0 1.1 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding DnaJ PF00226.31 KFP00576.1 - 1.9e-08 34.3 0.3 7.4e-08 32.4 0.3 2.1 1 0 0 1 1 1 1 DnaJ domain zf-met PF12874.7 KFP00576.1 - 3.8e-07 30.3 7.7 1.5e-06 28.4 1.2 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFP00576.1 - 7.9e-07 29.3 3.0 0.023 15.0 0.7 3.1 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFP00576.1 - 0.0038 17.9 3.9 1 10.4 0.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP00576.1 - 1.5 9.4 7.3 5 7.8 1.2 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFP00576.1 - 2.9 8.0 8.1 5.5 7.1 1.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger RVT_1 PF00078.27 KFP00577.1 - 0.12 11.8 0.0 6.4 6.2 0.0 2.4 3 0 0 3 3 3 0 Reverse transcriptase (RNA-dependent DNA polymerase) Aminotran_3 PF00202.21 KFP00578.1 - 8.2e-92 308.0 0.0 1.2e-91 307.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KFP00578.1 - 0.00033 19.9 0.0 0.11 11.6 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II EpoR_lig-bind PF09067.10 KFP00579.1 - 2.2e-46 156.3 0.4 2.5e-25 88.7 0.1 2.5 2 0 0 2 2 2 2 Erythropoietin receptor, ligand binding IL6Ra-bind PF09240.10 KFP00579.1 - 5.1e-21 74.9 1.8 3.4e-10 40.2 0.1 2.9 2 0 0 2 2 2 2 Interleukin-6 receptor alpha chain, binding fn3 PF00041.21 KFP00579.1 - 9.4e-16 57.9 10.5 1.4e-06 28.6 0.3 4.8 4 1 0 4 4 4 4 Fibronectin type III domain Tissue_fac PF01108.17 KFP00579.1 - 0.0013 18.6 8.8 1.6 8.6 0.0 4.4 4 0 0 4 4 4 2 Tissue factor GHBP PF12772.7 KFP00579.1 - 0.19 11.2 10.1 0.027 14.0 0.7 3.0 1 1 2 3 3 3 0 Growth hormone receptor binding PKD PF00801.20 KFP00579.1 - 4.2 7.3 5.9 21 5.0 0.1 3.3 4 0 0 4 4 4 0 PKD domain FN3_7 PF18447.1 KFP00580.1 - 6.9e-37 125.7 6.4 1.5e-36 124.6 6.4 1.6 1 0 0 1 1 1 1 Fibronectin type III domain EF-hand_1 PF00036.32 KFP00581.1 - 4.6e-24 82.1 8.5 1.8e-08 33.4 0.6 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KFP00581.1 - 2.7e-23 79.9 7.8 3.7e-07 29.5 0.0 4.6 4 1 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 KFP00581.1 - 1.3e-18 67.2 7.7 7.6e-09 35.9 3.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP00581.1 - 9.8e-15 53.3 14.6 2e-05 23.9 1.8 5.1 4 2 1 5 5 5 3 EF hand EF-hand_8 PF13833.6 KFP00581.1 - 9.5e-13 47.8 12.1 2.2e-05 24.2 1.0 3.6 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 KFP00581.1 - 2.6e-05 24.1 1.6 0.013 15.5 0.1 2.9 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand YugN PF08868.10 KFP00581.1 - 0.0065 16.4 0.9 0.065 13.1 0.2 2.1 1 1 0 2 2 2 1 YugN-like family SPARC_Ca_bdg PF10591.9 KFP00581.1 - 0.023 15.0 0.1 2.9 8.2 0.0 2.8 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KFP00581.1 - 0.047 13.5 0.6 0.64 9.9 0.7 2.6 2 1 1 3 3 3 0 EF hand EFhand_Ca_insen PF08726.10 KFP00581.1 - 0.062 13.4 0.8 3.9 7.6 0.0 3.2 4 0 0 4 4 4 0 Ca2+ insensitive EF hand TerB PF05099.13 KFP00581.1 - 0.12 12.3 0.0 0.64 10.0 0.0 2.1 1 1 1 2 2 2 0 Tellurite resistance protein TerB Phage_XkdX PF09693.10 KFP00581.1 - 0.17 11.9 1.2 4.1 7.5 0.0 3.0 3 0 0 3 3 3 0 Phage uncharacterised protein (Phage_XkdX) LMBR1 PF04791.16 KFP00582.1 - 2.4e-187 623.9 25.1 2.4e-187 623.9 25.1 1.4 2 0 0 2 2 2 1 LMBR1-like membrane protein F-box-like PF12937.7 KFP00583.1 - 3.8e-15 55.5 1.5 1.2e-14 53.9 1.5 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFP00583.1 - 1.4e-09 37.6 1.4 1.4e-09 37.6 1.4 2.5 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 KFP00583.1 - 0.00073 19.7 12.8 26 5.9 0.0 7.5 7 2 0 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.6 KFP00583.1 - 0.035 14.1 13.6 3.5 7.9 0.1 6.9 8 0 0 8 8 8 0 Leucine Rich repeat NAD_kinase PF01513.21 KFP00584.1 - 9.2e-10 38.2 0.0 1.8e-07 30.7 0.0 2.2 2 0 0 2 2 2 2 ATP-NAD kinase DAGK_cat PF00781.24 KFP00584.1 - 0.0041 16.7 0.0 0.0087 15.7 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain HTH_Tnp_Mu_1 PF02316.16 KFP00584.1 - 0.046 13.9 0.0 0.09 12.9 0.0 1.4 1 0 0 1 1 1 0 Mu DNA-binding domain TPALS PF18178.1 KFP00584.1 - 0.067 12.6 0.0 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 TIR- and PNP-associating SLOG family CE2_N PF17996.1 KFP00584.1 - 0.074 13.0 0.0 0.58 10.2 0.0 2.2 2 0 0 2 2 2 0 Carbohydrate esterase 2 N-terminal Ran_BP1 PF00638.18 KFP00585.1 - 4e-12 46.5 0.0 7.4e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain DUF778 PF05608.12 KFP00585.1 - 0.01 16.2 0.1 0.014 15.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF778) MAGI_u5 PF16666.5 KFP00585.1 - 1.1 9.4 9.3 7.6 6.7 2.9 2.5 2 0 0 2 2 2 0 Unstructured region on MAGI SDF PF00375.18 KFP00586.1 - 6.7e-134 446.8 32.7 7.7e-134 446.6 32.7 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family MT PF12777.7 KFP00586.1 - 0.016 14.2 0.1 0.027 13.5 0.1 1.3 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor DUF1270 PF06900.11 KFP00586.1 - 0.48 10.8 5.3 5.6 7.4 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) THP2 PF09432.10 KFP00589.1 - 0.013 15.6 0.2 0.018 15.1 0.2 1.3 1 0 0 1 1 1 0 Tho complex subunit THP2 Cohesin_HEAT PF12765.7 KFP00590.1 - 1.5e-13 50.8 0.2 2.3e-13 50.2 0.2 1.3 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 KFP00590.1 - 7.6e-06 25.8 0.5 0.0025 17.9 0.0 2.3 2 0 0 2 2 2 2 HEAT repeat HEAT_EZ PF13513.6 KFP00590.1 - 0.00053 20.4 0.2 0.0091 16.5 0.1 2.2 1 1 1 2 2 2 1 HEAT-like repeat Cnd3 PF12719.7 KFP00590.1 - 0.0013 18.0 0.1 0.055 12.7 0.0 2.0 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain DUF3385 PF11865.8 KFP00590.1 - 0.079 12.9 0.0 0.081 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) CcmH PF03918.14 KFP00590.1 - 0.097 12.0 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein CLASP_N PF12348.8 KFP00590.1 - 0.15 11.6 0.0 0.29 10.6 0.0 1.5 1 1 0 1 1 1 0 CLASP N terminal Nipped-B_C PF12830.7 KFP00591.1 - 3.6e-68 229.3 1.3 3.6e-68 229.3 1.3 2.3 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus HEAT_2 PF13646.6 KFP00591.1 - 0.00086 19.6 0.0 4 7.9 0.0 3.6 2 1 0 2 2 2 2 HEAT repeats DNA_repr_REX1B PF14966.6 KFP00591.1 - 0.019 15.6 0.0 0.061 14.0 0.0 1.8 1 0 0 1 1 1 0 DNA repair REX1-B Cnd1 PF12717.7 KFP00591.1 - 0.094 12.8 5.2 2.3 8.2 0.0 3.6 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KFP00591.1 - 0.16 12.5 0.0 7.3 7.2 0.0 3.5 3 0 0 3 3 3 0 HEAT-like repeat T3SS_basalb_I PF17001.5 KFP00591.1 - 0.32 11.6 7.3 1 10.0 1.8 3.6 3 0 0 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI DTHCT PF08070.11 KFP00591.1 - 0.54 11.0 13.7 0.084 13.6 8.4 2.5 2 0 0 2 2 2 0 DTHCT (NUC029) region Joubert PF15392.6 KFP00592.1 - 1e-23 84.7 5.8 1.1e-23 84.6 5.8 1.0 1 0 0 1 1 1 1 Joubert syndrome-associated Nucleoporin_N PF08801.11 KFP00596.1 - 3.7e-108 362.1 0.0 4.9e-108 361.7 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KFP00596.1 - 6.1e-20 71.5 11.3 9.2e-20 70.9 11.3 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nup160 PF11715.8 KFP00596.1 - 0.0033 16.1 0.0 0.0053 15.5 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 WD40 PF00400.32 KFP00597.1 - 2.7e-17 62.8 14.3 0.0013 19.5 0.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP00597.1 - 4e-09 36.7 0.9 0.17 12.2 0.0 5.9 4 1 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP00597.1 - 1.9e-05 23.8 0.4 0.0094 14.9 0.1 3.3 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein TGF_beta PF00019.20 KFP00598.1 - 3.4e-12 47.3 0.5 5.3e-12 46.6 0.5 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain M-inducer_phosp PF06617.13 KFP00598.1 - 0.037 13.3 1.0 0.054 12.8 1.0 1.2 1 0 0 1 1 1 0 M-phase inducer phosphatase Laminin_G_2 PF02210.24 KFP00599.1 - 1.9e-82 274.1 0.2 6.9e-29 101.0 0.1 3.4 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.23 KFP00599.1 - 1.1e-81 271.5 0.0 6.2e-26 91.2 0.0 3.3 3 0 0 3 3 3 3 Laminin G domain fn3 PF00041.21 KFP00599.1 - 4e-22 78.4 0.0 2e-11 44.1 0.0 2.7 2 0 0 2 2 2 2 Fibronectin type III domain EGF PF00008.27 KFP00599.1 - 5.7e-12 45.7 34.7 1e-07 32.1 7.1 3.6 3 0 0 3 3 3 2 EGF-like domain Laminin_G_3 PF13385.6 KFP00599.1 - 3.4e-10 40.3 0.1 0.041 14.0 0.1 3.4 3 0 0 3 3 3 3 Concanavalin A-like lectin/glucanases superfamily hEGF PF12661.7 KFP00599.1 - 5.3e-08 33.2 20.3 0.00019 21.9 3.8 4.0 3 0 0 3 3 3 2 Human growth factor-like EGF Stirrup PF09061.6 KFP00599.1 - 1.4e-07 31.6 0.2 0.011 15.9 0.0 3.4 3 0 0 3 3 3 2 Stirrup Pur_ac_phosph_N PF16656.5 KFP00599.1 - 3e-05 24.5 0.0 0.13 12.8 0.0 2.9 2 1 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain LIFR_D2 PF17971.1 KFP00600.1 - 1.9e-54 182.8 2.3 1.9e-54 182.8 2.3 3.8 3 1 0 3 3 3 1 Leukemia inhibitory factor receptor D2 domain fn3 PF00041.21 KFP00600.1 - 3.9e-22 78.4 3.6 9.5e-06 25.9 0.1 6.6 6 1 0 6 6 6 4 Fibronectin type III domain IL6Ra-bind PF09240.10 KFP00600.1 - 5.8e-08 33.0 1.4 0.0077 16.6 0.0 4.0 3 0 0 3 3 3 2 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.10 KFP00600.1 - 1.4e-05 25.2 0.3 0.09 13.0 0.1 2.9 2 0 0 2 2 2 2 Erythropoietin receptor, ligand binding LIFR_N PF18207.1 KFP00600.1 - 0.00052 20.3 0.2 0.00052 20.3 0.2 3.2 3 0 0 3 3 3 1 Leukemia inhibitory factor receptor N-terminal domain Pur_ac_phosph_N PF16656.5 KFP00600.1 - 0.00066 20.2 2.5 0.0014 19.1 0.2 2.9 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain LIFR_D2 PF17971.1 KFP00601.1 - 3.5e-16 59.4 5.5 3.5e-16 59.4 5.5 2.3 2 0 0 2 2 2 1 Leukemia inhibitory factor receptor D2 domain fn3 PF00041.21 KFP00601.1 - 3.8e-16 59.2 6.8 0.0003 21.1 0.1 6.1 5 1 0 5 5 5 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFP00601.1 - 0.00034 21.1 1.0 0.0094 16.5 0.1 3.0 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain RICTOR_N PF14664.6 KFP00602.1 - 5.4e-109 364.6 1.7 1.1e-108 363.5 1.7 1.6 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_phospho PF14665.6 KFP00602.1 - 2.2e-55 185.6 3.0 2.2e-55 185.6 3.0 2.1 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, phosphorylation-site RasGEF_N_2 PF14663.6 KFP00602.1 - 1.1e-36 125.4 0.5 1.1e-36 125.4 0.5 3.2 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 KFP00602.1 - 7.2e-33 112.5 3.7 1.5e-31 108.3 0.8 4.1 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 KFP00602.1 - 3.1e-32 110.6 1.5 7.9e-30 102.9 0.2 4.1 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_EZ PF13513.6 KFP00602.1 - 0.0089 16.5 3.2 0.68 10.5 0.1 4.0 3 0 0 3 3 3 1 HEAT-like repeat 7TM_GPCR_Srbc PF10316.9 KFP00602.1 - 0.069 12.7 3.1 2.1 7.8 0.0 2.6 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srbc hSH3 PF14603.6 KFP00603.1 - 1.5e-30 105.4 21.6 9e-22 77.3 0.0 5.9 5 2 1 6 6 6 2 Helically-extended SH3 domain SH3_2 PF07653.17 KFP00603.1 - 6.7e-07 28.9 0.1 1.6e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP00603.1 - 0.00028 20.5 0.1 0.22 11.2 0.0 2.6 2 0 0 2 2 2 2 SH3 domain DUF4651 PF15513.6 KFP00603.1 - 0.0016 18.2 0.0 2.7 7.9 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4651) 7tm_1 PF00001.21 KFP00604.1 - 9.7e-39 133.3 10.5 1.2e-38 133.0 10.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP00604.1 - 1.5e-10 41.2 14.8 2.2e-10 40.6 14.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx NdhL PF10716.9 KFP00604.1 - 0.0015 18.4 1.0 0.0075 16.2 0.0 2.5 2 0 0 2 2 2 1 NADH dehydrogenase transmembrane subunit 7TM_GPCR_Srb PF02175.16 KFP00604.1 - 0.0015 18.3 2.1 0.0048 16.7 2.1 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srb EIIC-GAT PF03611.14 KFP00604.1 - 0.13 11.3 3.5 0.088 11.9 0.2 2.0 2 0 0 2 2 2 0 PTS system sugar-specific permease component Gag_p30 PF02093.16 KFP00605.1 - 0.11 11.9 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Gag P30 core shell protein TPR_2 PF07719.17 KFP00606.1 - 1.1e-09 37.7 0.1 0.00041 20.3 0.2 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFP00606.1 - 2.1e-07 31.5 0.7 0.051 14.2 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFP00606.1 - 4e-05 23.2 0.0 0.0012 18.5 0.1 2.6 2 1 0 2 2 2 1 TPR repeat TPR_14 PF13428.6 KFP00606.1 - 5.3e-05 23.7 1.0 1.3 10.0 0.1 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFP00606.1 - 6.7e-05 23.0 1.0 0.0088 16.2 0.2 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFP00606.1 - 6.7e-05 22.5 0.0 0.34 10.8 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFP00606.1 - 0.00013 22.5 0.0 0.017 15.6 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFP00606.1 - 0.0015 18.7 2.4 0.11 12.9 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat ChAPs PF09295.10 KFP00606.1 - 0.0017 17.4 0.4 0.0023 17.0 0.4 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) Vasohibin PF14822.6 KFP00606.1 - 0.079 12.2 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Vasohibin Maf_N PF08383.11 KFP00606.1 - 0.53 10.1 5.7 0.54 10.1 0.3 2.9 3 0 0 3 3 3 0 Maf N-terminal region Pkinase PF00069.25 KFP00607.1 - 1.9e-69 234.0 0.0 2.5e-69 233.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP00607.1 - 9.8e-38 129.9 0.0 1.5e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KFP00607.1 - 3.3e-13 50.1 0.1 1.3e-12 48.2 0.0 2.0 2 0 0 2 2 2 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 KFP00607.1 - 1.7e-05 24.3 0.0 2.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFP00607.1 - 0.0025 17.4 0.1 0.0046 16.6 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KFP00607.1 - 0.0039 16.6 0.1 0.0082 15.5 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP00607.1 - 0.055 13.4 0.2 0.15 11.9 0.2 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFP00607.1 - 0.091 11.7 0.1 0.14 11.1 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Ribosomal_L37e PF01907.19 KFP00608.1 - 4.2e-27 94.1 15.1 7.7e-27 93.2 15.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 KFP00608.1 - 0.0064 16.5 1.7 0.01 15.8 1.7 1.3 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 KFP00608.1 - 0.23 11.5 1.4 0.32 11.0 1.4 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FeS PF04060.13 KFP00608.1 - 0.53 10.0 4.0 0.57 9.9 0.7 2.1 2 0 0 2 2 2 0 Putative Fe-S cluster MACPF PF01823.19 KFP00609.1 - 9e-38 130.5 2.2 1e-37 130.3 0.7 1.7 1 1 1 2 2 2 1 MAC/Perforin domain Kazal_3 PF18434.1 KFP00609.1 - 3.8e-19 68.2 7.7 3.8e-19 68.2 7.7 4.3 4 0 0 4 4 4 2 Kazal-type serine protease inhibitor domain Sushi PF00084.20 KFP00609.1 - 1.3e-17 64.1 6.0 8.1e-11 42.4 0.3 3.8 3 0 0 3 3 3 2 Sushi repeat (SCR repeat) TSP_1 PF00090.19 KFP00609.1 - 1.4e-08 34.8 22.7 6.6e-06 26.3 3.2 5.3 6 0 0 6 6 6 2 Thrombospondin type 1 domain Ldl_recept_a PF00057.18 KFP00609.1 - 3.2e-06 27.2 12.8 3.2e-06 27.2 12.8 4.5 4 0 0 4 4 4 1 Low-density lipoprotein receptor domain class A MACPF PF01823.19 KFP00610.1 - 4.9e-43 147.7 2.9 5.1e-43 147.6 1.3 1.7 2 0 0 2 2 2 1 MAC/Perforin domain Sushi PF00084.20 KFP00610.1 - 2.9e-14 53.4 3.4 7.7e-08 32.8 0.4 4.4 4 0 0 4 4 4 2 Sushi repeat (SCR repeat) TSP_1 PF00090.19 KFP00610.1 - 4.8e-14 52.3 41.8 1.9e-08 34.4 7.6 5.3 4 0 0 4 4 4 3 Thrombospondin type 1 domain Ldl_recept_a PF00057.18 KFP00610.1 - 3.3e-11 43.2 14.8 3.3e-11 43.2 14.8 4.3 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A PI-PLC-X PF00388.19 KFP00611.1 - 0.00042 19.9 0.0 0.00062 19.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain CoA_trans PF01144.23 KFP00612.1 - 1.4e-124 413.6 1.7 8e-76 254.2 0.4 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KFP00612.1 - 0.0013 18.6 0.1 0.0027 17.7 0.1 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DUF5561 PF17716.1 KFP00613.1 - 7.3e-114 379.3 4.8 8.4e-114 379.1 4.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5561) C1-set PF07654.15 KFP00614.1 - 4.9e-23 81.3 0.1 5.8e-23 81.1 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.6 KFP00614.1 - 0.00012 22.6 0.0 0.00016 22.2 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP00614.1 - 0.0023 18.0 0.1 0.0032 17.6 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP00614.1 - 0.0079 16.5 0.0 0.011 16.1 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP00614.1 - 0.032 14.3 0.0 0.043 13.9 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin I-set domain Marek_A PF02124.15 KFP00614.1 - 0.046 13.6 0.0 0.046 13.6 0.0 1.1 1 0 0 1 1 1 0 Marek's disease glycoprotein A DUF4505 PF14956.6 KFP00615.1 - 5e-58 195.8 0.0 5.6e-58 195.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4505) Histone PF00125.24 KFP00616.1 - 4.4e-06 27.1 0.0 4.8e-06 27.0 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFP00616.1 - 0.023 15.0 0.0 0.03 14.6 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFP00617.1 - 6.8e-54 181.7 2.3 7.6e-54 181.6 2.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KFP00617.1 - 8.4e-05 22.6 0.3 0.00015 21.8 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KFP00617.1 - 0.00019 22.0 1.2 0.00023 21.8 1.2 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 KFP00617.1 - 0.00042 20.6 0.0 0.00064 20.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KFP00617.1 - 0.011 16.0 0.1 0.022 15.0 0.1 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFP00617.1 - 0.11 12.6 0.1 0.21 11.7 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit 5_nucleotid PF05761.14 KFP00618.1 - 4.4e-59 200.6 0.1 5.8e-59 200.2 0.1 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.6 KFP00618.1 - 0.00033 20.8 0.4 0.023 14.8 0.4 3.0 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Collagen PF01391.18 KFP00619.1 - 1.7e-68 226.2 289.0 1.9e-08 34.0 34.1 10.3 1 1 7 8 8 8 7 Collagen triple helix repeat (20 copies) C1q PF00386.21 KFP00619.1 - 2.3e-38 131.3 0.1 3e-38 130.9 0.1 1.1 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 KFP00619.1 - 0.002 18.0 0.0 0.0031 17.4 0.0 1.1 1 0 0 1 1 1 1 BclA C-terminal domain CAP PF00188.26 KFP00620.1 - 2.7e-25 89.6 2.2 3.8e-25 89.2 2.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family LCCL PF03815.19 KFP00621.1 - 3.8e-49 164.8 17.4 4.8e-25 87.5 0.9 3.2 3 0 0 3 3 3 2 LCCL domain CAP PF00188.26 KFP00621.1 - 3.2e-20 73.2 1.4 3.2e-20 73.2 1.4 2.0 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Rxt3 PF08642.10 KFP00621.1 - 0.0069 17.2 2.5 0.12 13.1 0.0 3.0 3 0 0 3 3 3 1 Histone deacetylation protein Rxt3 DUF2889 PF11136.8 KFP00621.1 - 0.043 14.1 0.2 0.11 12.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2889) Hormone_recep PF00104.30 KFP00622.1 - 3e-42 144.5 0.1 4.8e-42 143.9 0.1 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFP00622.1 - 4.9e-29 100.6 17.1 8.6e-29 99.8 17.1 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Pex2_Pex12 PF04757.14 KFP00623.1 - 6.2e-38 130.6 5.5 8.6e-38 130.2 5.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.25 KFP00623.1 - 2.3e-08 33.8 9.1 2.3e-08 33.8 9.1 2.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP00623.1 - 0.00015 21.6 6.6 0.00037 20.3 6.6 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFP00623.1 - 0.00036 20.5 7.8 0.00036 20.5 7.8 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFP00623.1 - 0.00062 19.6 9.5 0.00062 19.6 9.5 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFP00623.1 - 0.0016 18.6 11.6 0.0035 17.5 11.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KFP00623.1 - 0.0032 17.3 9.2 0.0056 16.5 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP00623.1 - 0.018 15.0 11.9 0.018 15.0 11.9 2.4 3 0 0 3 3 3 0 zinc-RING finger domain zf-RING_2 PF13639.6 KFP00623.1 - 0.024 14.9 8.9 0.067 13.5 8.9 1.8 1 0 0 1 1 1 0 Ring finger domain RDD PF06271.12 KFP00623.1 - 0.031 14.5 1.1 0.19 11.9 1.1 2.0 1 1 0 1 1 1 0 RDD family zf-RING_6 PF14835.6 KFP00623.1 - 0.57 10.1 4.7 1.6 8.6 4.7 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zinc-ribbons_6 PF07191.12 KFP00623.1 - 1.5 8.8 7.6 1.6 8.8 5.9 1.9 2 0 0 2 2 2 0 zinc-ribbons zf-rbx1 PF12678.7 KFP00623.1 - 9.5 6.6 12.0 2.8 8.3 8.8 1.8 2 0 0 2 2 2 0 RING-H2 zinc finger domain PKI PF02827.16 KFP00624.1 - 1.8e-29 101.8 0.3 2.1e-29 101.5 0.3 1.1 1 0 0 1 1 1 1 cAMP-dependent protein kinase inhibitor zf-C2HC_2 PF13913.6 KFP00625.1 - 4.9e-14 51.8 6.9 1.2e-08 34.6 0.6 2.6 2 0 0 2 2 2 2 zinc-finger of a C2HC-type Zf_RING PF16744.5 KFP00625.1 - 0.018 15.1 0.7 0.81 9.8 0.0 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger DZR PF12773.7 KFP00625.1 - 0.036 14.1 13.1 0.13 12.3 3.5 3.2 3 0 0 3 3 3 0 Double zinc ribbon DUF2321 PF10083.9 KFP00625.1 - 0.086 12.5 2.7 0.32 10.6 2.8 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-C2H2 PF00096.26 KFP00625.1 - 0.14 12.7 14.9 0.32 11.5 0.1 4.1 4 0 0 4 4 3 0 Zinc finger, C2H2 type TRAF6_Z2 PF18048.1 KFP00625.1 - 0.15 12.2 0.3 0.15 12.2 0.3 2.0 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 UL42 PF17638.2 KFP00625.1 - 0.16 11.9 4.2 0.25 11.3 0.9 2.7 3 0 0 3 3 3 0 HCMV UL42 zf-C2H2_4 PF13894.6 KFP00625.1 - 0.87 10.6 0.1 0.56 11.2 0.6 4.3 5 0 0 5 5 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP00625.1 - 1.4 9.3 4.7 8.7 6.8 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding HypA PF01155.19 KFP00625.1 - 1.4 9.0 9.0 2.1 8.4 1.6 2.9 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_6 PF13912.6 KFP00625.1 - 4.7 7.3 6.8 20 5.3 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zinc_ribbon_4 PF13717.6 KFP00625.1 - 5.2 7.1 8.2 29 4.7 1.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Stathmin PF00836.19 KFP00627.1 - 5e-57 191.7 24.9 6.3e-57 191.3 24.9 1.1 1 0 0 1 1 1 1 Stathmin family CCDC84 PF14968.6 KFP00627.1 - 0.054 13.1 4.4 0.054 13.1 4.4 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 FmdE PF02663.14 KFP00627.1 - 0.37 10.8 6.4 2.2 8.3 6.4 2.0 1 1 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Type2_restr_D3 PF16902.5 KFP00627.1 - 1.5 8.8 4.9 9.5 6.2 0.2 2.5 1 1 0 2 2 2 0 Type-2 restriction enzyme D3 domain Exonuc_VII_L PF02601.15 KFP00627.1 - 3.2 7.2 10.3 3.7 7.0 10.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HLH PF00010.26 KFP00628.1 - 3.6e-17 62.1 1.1 5.6e-17 61.5 1.1 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 KFP00628.1 - 1e-11 44.8 0.0 1.7e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Hairy Orange dCache_2 PF08269.11 KFP00628.1 - 0.048 12.8 0.0 0.069 12.3 0.0 1.1 1 0 0 1 1 1 0 Cache domain MRP-S35 PF10246.9 KFP00629.1 - 2.3e-53 178.6 0.1 2.7e-53 178.4 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein MRP-S35 S1 PF00575.23 KFP00629.1 - 0.0027 18.0 0.0 0.0042 17.4 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain TPD52 PF04201.15 KFP00630.1 - 7.1e-75 250.1 7.3 8.1e-75 249.9 7.3 1.0 1 0 0 1 1 1 1 Tumour protein D52 family PEP-utilisers_N PF05524.13 KFP00630.1 - 0.002 18.3 1.8 0.0034 17.5 1.8 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal Occludin_ELL PF07303.13 KFP00630.1 - 0.0038 17.9 2.3 0.3 11.8 0.1 2.3 1 1 1 2 2 2 1 Occludin homology domain WXG100 PF06013.12 KFP00630.1 - 0.01 16.0 5.3 0.49 10.7 0.4 2.9 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Uds1 PF15456.6 KFP00630.1 - 0.014 15.5 8.5 0.03 14.5 8.5 1.6 1 1 0 1 1 1 0 Up-regulated During Septation AAA_13 PF13166.6 KFP00630.1 - 0.025 13.2 7.7 0.24 10.0 0.6 2.0 1 1 1 2 2 2 0 AAA domain Cob_adeno_trans PF01923.18 KFP00630.1 - 0.026 14.7 2.4 0.038 14.1 2.2 1.3 1 1 0 1 1 1 0 Cobalamin adenosyltransferase SKA1 PF07160.12 KFP00630.1 - 0.031 14.1 1.9 0.041 13.7 1.9 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Atg14 PF10186.9 KFP00630.1 - 0.058 12.5 4.0 0.078 12.0 4.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 KFP00630.1 - 0.071 13.6 6.7 0.069 13.7 5.3 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region RNA_pol_A_CTD PF03118.15 KFP00630.1 - 0.074 12.8 2.4 0.097 12.4 1.0 1.9 2 1 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain Metal_resist PF13801.6 KFP00630.1 - 0.092 12.9 0.6 0.19 11.9 0.5 1.6 2 0 0 2 2 1 0 Heavy-metal resistance GvpK PF05121.12 KFP00630.1 - 0.13 12.3 2.4 1.4 9.0 3.0 2.3 2 1 0 2 2 2 0 Gas vesicle protein K KxDL PF10241.9 KFP00630.1 - 0.13 12.6 4.3 13 6.1 0.1 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein HsbA PF12296.8 KFP00630.1 - 0.16 12.4 6.6 0.44 11.0 0.9 2.6 1 1 2 3 3 3 0 Hydrophobic surface binding protein A Wx5_PLAF3D7 PF09688.10 KFP00630.1 - 0.16 12.0 4.1 0.22 11.5 3.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) SlyX PF04102.12 KFP00630.1 - 0.17 12.5 4.5 4.8 7.9 5.2 2.6 2 1 1 3 3 2 0 SlyX TBCC_N PF16752.5 KFP00630.1 - 0.19 12.2 6.6 0.066 13.7 2.2 2.1 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Cnn_1N PF07989.11 KFP00630.1 - 0.39 10.9 9.7 0.057 13.6 4.5 2.2 3 0 0 3 3 2 0 Centrosomin N-terminal motif 1 TMF_DNA_bd PF12329.8 KFP00630.1 - 0.42 10.6 13.1 0.11 12.5 7.3 2.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding OmpH PF03938.14 KFP00630.1 - 0.54 10.6 9.1 0.75 10.1 7.9 1.8 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) FlaC_arch PF05377.11 KFP00630.1 - 0.84 10.1 5.1 7.6 7.0 1.0 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) TMPIT PF07851.13 KFP00630.1 - 1.2 8.3 4.9 1.8 7.7 4.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein Prefoldin_2 PF01920.20 KFP00630.1 - 3.4 7.7 12.1 3.8 7.5 8.7 2.4 1 1 1 2 2 2 0 Prefoldin subunit BTB PF00651.31 KFP00631.1 - 6e-24 84.4 0.2 9.4e-24 83.8 0.2 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_5 PF13909.6 KFP00631.1 - 4e-10 39.2 1.0 4e-10 39.2 1.0 3.2 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KFP00631.1 - 1.1e-08 35.1 16.7 0.00036 20.8 0.1 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFP00631.1 - 2.7e-05 24.4 18.5 0.0069 16.8 1.9 4.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP00631.1 - 4.5e-05 23.9 13.5 0.076 13.9 1.9 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger DUF3342 PF11822.8 KFP00631.1 - 0.00012 22.2 0.2 0.00027 21.1 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Ogr_Delta PF04606.12 KFP00631.1 - 0.23 11.5 4.5 0.21 11.6 1.5 2.4 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Ribosomal_L37ae PF01780.19 KFP00631.1 - 2.6 8.2 5.7 2.6 8.2 1.4 2.4 1 1 1 2 2 2 0 Ribosomal L37ae protein family zf-C2H2_6 PF13912.6 KFP00631.1 - 3.2 7.9 5.8 4.5 7.4 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 KFP00631.1 - 3.3 8.2 12.9 0.79 10.2 0.3 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFP00631.1 - 3.9 7.8 10.8 5.8 7.3 2.6 2.9 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KFP00632.1 - 0.007 16.8 0.6 0.02 15.3 0.1 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type MRP_L53 PF10780.9 KFP00634.1 - 2.4e-17 62.8 0.0 3.9e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Lipocalin PF00061.23 KFP00636.1 - 1.2e-20 74.2 1.4 1.3e-20 74.0 1.4 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 KFP00636.1 - 0.016 15.2 1.4 0.049 13.6 1.4 1.7 1 1 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family PhnA PF03831.14 KFP00636.1 - 0.081 12.8 0.7 0.46 10.4 0.1 2.0 2 0 0 2 2 2 0 PhnA domain DUF1967 PF09269.11 KFP00636.1 - 0.095 12.7 0.3 0.41 10.6 0.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1967) Lipocalin PF00061.23 KFP00637.1 - 4.7e-24 85.2 0.5 5.2e-24 85.1 0.5 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 KFP00637.1 - 5.9e-05 23.0 1.2 9.8e-05 22.3 1.2 1.4 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family SCVP PF17619.2 KFP00637.1 - 0.003 18.4 0.2 0.022 15.6 0.2 2.2 2 1 0 2 2 2 1 Secreted clade V proteins Lipocalin PF00061.23 KFP00638.1 - 6.3e-26 91.3 3.8 7e-26 91.2 3.8 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 KFP00638.1 - 0.00024 21.1 2.3 0.00032 20.6 2.3 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family SCVP PF17619.2 KFP00638.1 - 0.042 14.7 2.4 1.5 9.8 2.0 2.7 2 1 0 2 2 2 0 Secreted clade V proteins Inositol_P PF00459.25 KFP00639.1 - 3e-85 286.0 0.0 3.6e-85 285.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family zf-AN1 PF01428.16 KFP00640.1 - 1.6e-21 76.1 25.9 9.7e-13 48.1 12.3 2.9 3 0 0 3 3 3 2 AN1-like Zinc finger EndoU_bacteria PF14436.6 KFP00640.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial EndoU nuclease Transp_Tc5_C PF04236.15 KFP00640.1 - 9 6.7 12.7 0.59 10.5 4.0 2.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Snf7 PF03357.21 KFP00641.1 - 2.1e-52 177.2 17.5 2.9e-52 176.8 17.5 1.2 1 0 0 1 1 1 1 Snf7 GNAT_acetyltr_2 PF13718.6 KFP00641.1 - 2.4 7.5 5.6 0.31 10.4 0.8 1.8 2 0 0 2 2 2 0 GNAT acetyltransferase 2 V_ATPase_I PF01496.19 KFP00641.1 - 9.2 4.0 9.8 12 3.6 9.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PX PF00787.24 KFP00642.1 - 5.8e-19 68.2 0.8 8.8e-19 67.6 0.0 1.7 2 0 0 2 2 2 1 PX domain DUF641 PF04859.12 KFP00642.1 - 0.00095 19.5 1.6 0.0091 16.3 1.1 2.2 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) DUF4600 PF15372.6 KFP00642.1 - 0.37 11.2 6.3 0.16 12.4 3.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) IES5 PF17335.2 KFP00644.1 - 0.013 15.8 1.3 0.019 15.2 1.3 1.2 1 0 0 1 1 1 0 Ino80 complex subunit 5 Alpha-2-MRAP_C PF06401.11 KFP00644.1 - 0.013 15.4 2.9 0.018 15.0 2.9 1.1 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain Golgin_A5 PF09787.9 KFP00644.1 - 0.014 14.8 4.5 0.018 14.6 4.5 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 SKA2 PF16740.5 KFP00644.1 - 0.016 15.0 2.5 0.023 14.5 2.5 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 SR-25 PF10500.9 KFP00644.1 - 0.026 14.2 5.1 0.032 13.8 5.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein XhlA PF10779.9 KFP00644.1 - 0.082 13.1 6.0 0.14 12.4 6.0 1.4 1 0 0 1 1 1 0 Haemolysin XhlA RP-C_C PF11800.8 KFP00644.1 - 0.092 12.8 2.4 0.12 12.4 2.4 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4349 PF14257.6 KFP00644.1 - 0.18 11.2 1.3 0.29 10.6 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) PIEZO PF15917.5 KFP00644.1 - 0.22 11.0 3.7 0.3 10.5 3.7 1.1 1 0 0 1 1 1 0 Piezo PA26 PF04636.13 KFP00644.1 - 0.24 10.3 1.6 0.3 10.0 1.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4407 PF14362.6 KFP00644.1 - 0.31 10.3 3.0 0.4 10.0 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4611 PF15387.6 KFP00644.1 - 7.2 6.9 14.2 0.082 13.1 5.5 2.0 1 1 1 2 2 1 0 Domain of unknown function (DUF4611) DUF4614 PF15391.6 KFP00645.1 - 6.7e-18 65.3 0.3 8.3e-18 65.0 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4614) CTD_bind PF04818.13 KFP00646.1 - 1.7e-18 67.2 1.4 4.8e-18 65.7 0.6 2.3 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Surp PF01805.20 KFP00646.1 - 4.3e-17 61.8 0.4 1.5e-16 60.1 0.4 2.0 1 0 0 1 1 1 1 Surp module G-patch PF01585.23 KFP00646.1 - 2e-11 43.6 4.6 4.3e-11 42.5 4.6 1.6 1 0 0 1 1 1 1 G-patch domain Apt1 PF10351.9 KFP00646.1 - 0.16 10.8 13.2 0.25 10.1 13.2 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 KFP00646.1 - 1.2 7.8 7.2 2.5 6.8 7.2 1.4 1 0 0 1 1 1 0 Presenilin TPT PF03151.16 KFP00647.1 - 1e-80 271.2 16.8 1.2e-80 271.0 16.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFP00647.1 - 4.1e-15 56.2 21.8 7.1e-10 39.2 12.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KFP00647.1 - 0.00021 20.6 16.9 0.00027 20.3 16.9 1.1 1 0 0 1 1 1 1 UAA transporter family TMEM234 PF10639.9 KFP00647.1 - 0.17 11.9 7.7 2.5 8.2 1.5 2.4 2 0 0 2 2 2 0 Putative transmembrane family 234 YwiC PF14256.6 KFP00647.1 - 0.35 11.2 5.3 0.21 11.9 0.4 2.4 1 1 1 2 2 2 0 YwiC-like protein PRP38_assoc PF12871.7 KFP00648.1 - 2.3 8.9 125.6 1.8e+04 -45.7 125.6 3.5 1 1 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Med26_C PF15693.5 KFP00649.1 - 8.4e-92 306.4 1.4 9.5e-92 306.2 1.4 1.0 1 0 0 1 1 1 1 Mediator complex subunit 26 C-terminal Pullulanase_N2 PF17967.1 KFP00649.1 - 0.009 16.9 0.1 0.013 16.4 0.1 1.2 1 0 0 1 1 1 1 Pullulanase N2 domain SLY PF12485.8 KFP00649.1 - 0.025 15.3 1.1 0.037 14.8 1.1 1.2 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein UBD PF16455.5 KFP00649.1 - 0.037 14.3 0.1 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-binding domain TRIC PF05197.13 KFP00651.1 - 1.6e-80 269.2 7.7 1.9e-80 269.0 7.7 1.1 1 0 0 1 1 1 1 TRIC channel BAR PF03114.18 KFP00652.1 - 2.2e-41 142.1 8.5 2.6e-41 141.8 8.5 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KFP00652.1 - 4.2e-14 51.9 0.1 9.8e-14 50.7 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP00652.1 - 6.2e-12 45.2 0.1 9.7e-12 44.6 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP00652.1 - 9.4e-12 44.4 0.0 2e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.9 KFP00652.1 - 2.5e-08 33.4 6.9 3.2e-08 33.1 6.9 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 KFP00652.1 - 0.0059 16.3 4.5 0.013 15.2 4.5 1.5 1 1 0 1 1 1 1 BAR domain of APPL family Prefoldin_3 PF13758.6 KFP00652.1 - 0.036 14.1 1.6 0.063 13.3 1.6 1.3 1 0 0 1 1 1 0 Prefoldin subunit SPRY PF00622.28 KFP00653.1 - 1.4e-10 41.3 0.2 2.8e-10 40.4 0.1 1.6 2 0 0 2 2 2 1 SPRY domain fn3 PF00041.21 KFP00653.1 - 3.4e-07 30.5 0.0 2e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 Fibronectin type III domain fn3_4 PF16794.5 KFP00653.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Fibronectin-III type domain DUF572 PF04502.13 KFP00654.1 - 1.3e-95 320.8 19.0 1.4e-95 320.7 19.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) FERM_M PF00373.18 KFP00654.1 - 0.06 13.8 0.7 0.074 13.5 0.7 1.3 1 0 0 1 1 1 0 FERM central domain YceD PF02620.17 KFP00654.1 - 1.4 9.1 7.9 24 5.1 7.1 2.9 2 1 0 2 2 2 0 Large ribosomal RNA subunit accumulation protein YceD Autophagy_N PF03986.13 KFP00654.1 - 8 6.4 10.7 66 3.4 10.7 2.2 1 1 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain RRM_1 PF00076.22 KFP00655.1 - 3.7e-53 177.3 0.1 5.7e-19 67.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M PF11532.8 KFP00655.1 - 4.7e-18 65.1 8.7 1e-17 64.0 8.7 1.6 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein M Collagen_mid PF15984.5 KFP00655.1 - 3.6e-05 23.6 0.1 0.0019 18.0 0.1 2.5 1 1 1 2 2 2 1 Bacterial collagen, middle region RRM_3 PF08777.11 KFP00655.1 - 4.9e-05 23.3 0.3 0.21 11.7 0.0 2.9 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.8 KFP00655.1 - 7.3e-05 22.8 0.2 0.0047 17.0 0.0 2.6 2 1 0 2 2 2 1 Limkain b1 RRM_5 PF13893.6 KFP00655.1 - 0.00092 18.8 0.0 0.15 11.6 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP00655.1 - 0.0087 15.9 0.0 0.21 11.5 0.0 2.3 2 0 0 2 2 2 1 Occluded RNA-recognition motif Flagellin_C PF00700.21 KFP00655.1 - 0.046 14.1 0.0 11 6.4 0.0 2.8 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region DUF3932 PF13068.6 KFP00655.1 - 0.047 14.0 0.0 1.6 9.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3932) Tim44 PF04280.15 KFP00656.1 - 8.9e-43 145.9 0.3 3.1e-42 144.1 0.0 2.0 2 0 0 2 2 2 1 Tim44-like domain Kinase-PolyVal PF18762.1 KFP00656.1 - 0.027 14.4 0.2 0.059 13.3 0.2 1.5 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins DUF5089 PF17002.5 KFP00656.1 - 0.13 12.1 17.3 1.1 9.1 15.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5089) DUF1931 PF09123.11 KFP00656.1 - 0.23 11.6 2.9 0.68 10.0 0.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1931) DUF3347 PF11827.8 KFP00656.1 - 1.1 9.4 13.4 3.9 7.6 4.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3347) RecG_N PF17190.4 KFP00656.1 - 2.2 9.1 8.0 5.7 7.7 3.4 3.3 2 1 1 3 3 3 0 RecG N-terminal helical domain AIM3 PF17096.5 KFP00656.1 - 2.3 9.2 8.0 0.12 13.3 0.7 2.2 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 PIN_8 PF18476.1 KFP00656.1 - 6.7 6.5 13.5 11 5.7 8.9 2.4 1 1 1 2 2 2 0 PIN like domain EGF_CA PF07645.15 KFP00657.1 - 0 1025.7 739.8 6.1e-11 42.3 5.1 48.5 50 1 0 50 50 50 44 Calcium-binding EGF domain cEGF PF12662.7 KFP00657.1 - 7.8e-212 684.3 404.9 9.8e-09 35.0 1.3 50.1 49 0 0 49 49 49 44 Complement Clr-like EGF-like TB PF00683.17 KFP00657.1 - 1.2e-120 393.0 154.3 9.7e-16 57.2 10.0 11.1 9 0 0 9 9 9 9 TB domain EGF PF00008.27 KFP00657.1 - 7.8e-103 336.2 676.0 0.00041 20.6 5.6 49.1 48 0 0 48 48 48 44 EGF-like domain FXa_inhibition PF14670.6 KFP00657.1 - 3.4e-90 296.0 719.2 2e-08 34.3 11.4 48.4 46 3 3 49 49 49 42 Coagulation Factor Xa inhibitory site hEGF PF12661.7 KFP00657.1 - 6.4e-72 236.0 669.6 0.00047 20.7 6.0 53.0 53 0 0 53 53 53 40 Human growth factor-like EGF EGF_3 PF12947.7 KFP00657.1 - 2e-48 162.3 608.7 2.7e-09 37.1 5.3 49.1 47 1 0 47 47 47 39 EGF domain Fibrillin_U_N PF18193.1 KFP00657.1 - 5.3e-25 87.2 7.7 5.3e-25 87.2 7.7 11.0 11 0 0 11 11 11 1 Fibrillin 1 unique N-terminal domain Plasmod_Pvs28 PF06247.11 KFP00657.1 - 0.0019 18.5 501.0 0.015 15.6 1.0 44.4 41 4 4 45 45 45 25 Pvs28 EGF domain FlxA PF14282.6 KFP00658.1 - 0.0015 18.4 18.8 0.015 15.2 0.1 3.6 1 1 2 3 3 3 2 FlxA-like protein AAA_13 PF13166.6 KFP00658.1 - 0.014 14.0 15.3 0.019 13.7 15.3 1.1 1 0 0 1 1 1 0 AAA domain Syntaxin_2 PF14523.6 KFP00658.1 - 0.57 10.6 6.1 18 5.7 0.3 3.3 1 1 3 4 4 4 0 Syntaxin-like protein TMF_DNA_bd PF12329.8 KFP00658.1 - 0.59 10.2 27.0 0.92 9.5 0.3 4.9 3 1 2 5 5 5 0 TATA element modulatory factor 1 DNA binding Tropomyosin PF00261.20 KFP00658.1 - 1.3 8.3 36.5 0.55 9.6 17.1 3.4 1 1 2 3 3 3 0 Tropomyosin Flagellin_N PF00669.20 KFP00658.1 - 1.7 8.8 15.4 0.078 13.1 2.2 3.1 2 2 2 4 4 4 0 Bacterial flagellin N-terminal helical region DUF1664 PF07889.12 KFP00658.1 - 2.3 8.3 9.8 13 5.9 0.7 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 KFP00658.1 - 3.6 8.0 10.7 0.76 10.1 1.5 3.2 2 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CAP_N PF01213.19 KFP00658.1 - 3.7 6.9 14.0 0.39 10.1 9.6 1.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal MscS_porin PF12795.7 KFP00658.1 - 4.6 6.7 41.7 6.3e+02 -0.3 34.6 3.0 1 1 1 2 2 1 0 Mechanosensitive ion channel porin domain Tropomyosin_1 PF12718.7 KFP00658.1 - 5 7.3 30.2 0.79 9.9 15.2 3.1 1 1 0 2 2 2 0 Tropomyosin like Occludin_ELL PF07303.13 KFP00658.1 - 7.3 7.4 7.8 7.4 7.4 0.5 3.0 1 1 2 3 3 3 0 Occludin homology domain SIR2 PF02146.17 KFP00659.1 - 1.5e-26 93.4 0.0 3.6e-18 66.1 0.0 2.2 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 KFP00659.1 - 0.0002 21.1 0.0 0.026 14.3 0.0 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain bZIP_1 PF00170.21 KFP00660.1 - 1.1e-12 47.9 15.6 1.8e-12 47.1 14.4 1.9 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 KFP00660.1 - 3.1e-09 36.8 10.3 3.1e-09 36.8 10.3 2.2 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.17 KFP00660.1 - 4.2e-05 24.0 11.5 7.3e-05 23.2 11.5 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor ZapB PF06005.12 KFP00660.1 - 0.0045 17.4 6.3 0.0045 17.4 6.3 1.7 1 1 1 2 2 2 1 Cell division protein ZapB DUF2207 PF09972.9 KFP00660.1 - 0.039 12.7 0.1 0.052 12.3 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4407 PF14362.6 KFP00660.1 - 0.094 12.1 0.5 0.13 11.6 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) pEK499_p136 PF18736.1 KFP00660.1 - 0.11 12.2 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 HEPN pEK499 p136 MCU PF04678.13 KFP00660.1 - 0.12 12.5 1.2 0.18 11.9 1.2 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF1664 PF07889.12 KFP00660.1 - 0.13 12.3 1.9 0.18 11.8 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ADIP PF11559.8 KFP00660.1 - 0.15 12.1 14.5 0.22 11.6 14.5 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding EMP24_GP25L PF01105.24 KFP00660.1 - 0.19 11.6 1.1 0.27 11.2 1.1 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD ARHGEF5_35 PF15441.6 KFP00660.1 - 0.41 9.6 4.8 0.55 9.1 4.8 1.1 1 0 0 1 1 1 0 Rho guanine nucleotide exchange factor 5/35 DUF724 PF05266.14 KFP00660.1 - 0.44 10.3 5.2 0.66 9.8 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) RNA_polI_A14 PF08203.11 KFP00660.1 - 0.5 11.1 3.7 0.91 10.3 3.7 1.4 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 SOGA PF11365.8 KFP00660.1 - 0.88 10.7 9.1 0.77 10.9 7.4 1.7 1 1 1 2 2 2 0 Protein SOGA V_ATPase_I PF01496.19 KFP00660.1 - 5 4.9 4.8 6.5 4.5 4.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pkinase PF00069.25 KFP00661.1 - 6.1e-61 206.1 0.0 9.3e-61 205.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP00661.1 - 3e-34 118.5 0.0 1.3e-32 113.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP00661.1 - 8.8e-05 21.5 0.0 0.00012 20.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFP00661.1 - 0.0038 16.2 0.0 0.0053 15.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFP00661.1 - 0.0055 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFP00661.1 - 0.015 15.3 0.0 0.028 14.3 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFP00661.1 - 0.029 13.4 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 KFP00661.1 - 0.2 11.0 0.5 0.31 10.3 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PINIT PF14324.6 KFP00662.1 - 1.3e-31 109.9 0.4 2.1e-31 109.3 0.4 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KFP00662.1 - 7e-22 76.9 5.7 1.8e-21 75.6 5.7 1.8 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.27 KFP00662.1 - 2.9e-05 23.7 0.1 0.00017 21.3 0.0 2.2 2 0 0 2 2 2 1 SAP domain zf-Nse PF11789.8 KFP00662.1 - 5e-05 23.0 1.7 5e-05 23.0 1.7 1.8 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit GTP_EFTU PF00009.27 KFP00663.1 - 4.8e-65 218.8 0.0 6.5e-65 218.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KFP00663.1 - 2e-33 114.7 0.0 8.7e-33 112.7 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KFP00663.1 - 6.7e-23 80.5 0.0 1.5e-22 79.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KFP00663.1 - 2.1e-13 50.1 0.0 4.9e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KFP00663.1 - 1.2e-12 48.0 0.2 7.5e-12 45.5 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFP00663.1 - 1.5e-05 25.0 0.1 3.3e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Pkinase PF00069.25 KFP00664.1 - 4.2e-76 255.8 0.0 4.8e-76 255.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP00664.1 - 3.5e-37 128.1 0.0 4e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFP00664.1 - 1.8e-06 27.5 0.2 3.5e-06 26.5 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFP00664.1 - 9.3e-06 25.4 0.1 1.3e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KFP00664.1 - 0.04 13.5 0.1 0.07 12.7 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF3847 PF12958.7 KFP00664.1 - 0.044 13.9 0.1 0.14 12.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) FTA2 PF13095.6 KFP00664.1 - 0.077 12.6 0.1 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Glycos_trans_3N PF02885.17 KFP00664.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain APH PF01636.23 KFP00664.1 - 0.18 11.7 0.1 0.43 10.5 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family AAA_18 PF13238.6 KFP00665.1 - 4.6e-09 36.9 0.0 7.8e-09 36.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 KFP00665.1 - 0.0053 16.5 0.9 0.17 11.6 0.9 2.2 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.23 KFP00665.1 - 0.0054 16.8 0.2 0.023 14.8 0.2 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KFP00665.1 - 0.019 15.2 0.0 0.057 13.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 KFP00665.1 - 0.093 12.6 1.0 0.33 10.8 0.1 2.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B T2SSE PF00437.20 KFP00665.1 - 0.11 11.5 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein BNIP2 PF12496.8 KFP00666.1 - 6.6e-42 143.2 0.3 1.1e-41 142.4 0.3 1.3 1 0 0 1 1 1 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CRAL_TRIO_2 PF13716.6 KFP00666.1 - 5.4e-32 110.8 0.3 7.1e-32 110.5 0.3 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KFP00666.1 - 2e-07 30.9 0.2 2.9e-07 30.3 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain TGF_beta PF00019.20 KFP00667.1 - 9.6e-12 45.8 0.6 1.5e-11 45.2 0.6 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain Dus PF01207.17 KFP00668.1 - 7.1e-58 196.1 0.0 9.9e-58 195.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 KFP00668.1 - 9.4e-07 28.5 12.2 1.2e-06 28.2 3.1 3.7 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFP00668.1 - 0.0025 17.8 9.7 0.04 14.0 0.7 2.8 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KFP00668.1 - 0.013 15.4 15.1 0.11 12.5 1.0 3.3 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FMN_dh PF01070.18 KFP00668.1 - 0.019 14.0 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase PEP_mutase PF13714.6 KFP00668.1 - 0.022 14.2 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase DUF4611 PF15387.6 KFP00668.1 - 0.6 10.4 9.9 0.03 14.6 3.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CDC45 PF02724.14 KFP00668.1 - 2.1 6.5 4.7 3 6.0 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-CCCH_2 PF14608.6 KFP00668.1 - 4.9 7.8 7.5 7.4 7.2 0.9 3.0 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger La PF05383.17 KFP00669.1 - 6.1e-21 74.2 0.6 9.3e-21 73.7 0.6 1.3 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KFP00669.1 - 0.0058 16.4 0.0 1.8 8.4 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNR_N PF08343.10 KFP00669.1 - 0.14 12.2 0.1 0.34 11.0 0.1 1.6 2 0 0 2 2 2 0 Ribonucleotide reductase N-terminal RFX1_trans_act PF04589.13 KFP00670.1 - 2.5e-55 187.0 18.6 2.5e-55 187.0 18.6 2.8 3 0 0 3 3 3 1 RFX1 transcription activation region RFX_DNA_binding PF02257.15 KFP00670.1 - 2.2e-29 101.9 0.1 7.4e-29 100.2 0.1 1.9 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 KFP00670.1 - 0.073 13.6 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Poxvirus D5 protein-like DUF2258 PF10015.9 KFP00670.1 - 0.14 12.3 0.2 0.32 11.1 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) Fibrinogen_C PF00147.18 KFP00671.1 - 2.8e-62 210.4 0.2 2.8e-62 210.4 0.2 1.4 2 0 0 2 2 2 1 Fibrinogen beta and gamma chains, C-terminal globular domain DivIC PF04977.15 KFP00671.1 - 0.059 13.2 4.5 0.12 12.2 4.5 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4625 PF15418.6 KFP00671.1 - 0.14 12.4 0.0 0.4 10.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4625) UPF0242 PF06785.11 KFP00671.1 - 0.45 10.6 8.9 0.066 13.3 5.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Ras PF00071.22 KFP00672.1 - 3.6e-63 212.0 0.1 4.3e-63 211.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP00672.1 - 8.4e-35 119.6 0.1 1.4e-34 118.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP00672.1 - 2.6e-12 46.6 0.1 3.3e-12 46.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP00672.1 - 3.3e-07 30.4 0.1 5.5e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KFP00672.1 - 3.4e-05 24.1 0.1 0.00046 20.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KFP00672.1 - 6e-05 23.0 0.3 0.023 14.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFP00672.1 - 8.8e-05 22.1 0.1 0.00023 20.7 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFP00672.1 - 0.0065 16.9 0.1 0.011 16.1 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 KFP00672.1 - 0.0082 15.5 0.1 0.015 14.6 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.6 KFP00672.1 - 0.021 14.8 0.1 0.064 13.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 KFP00672.1 - 0.022 14.2 0.0 0.051 13.0 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KFP00672.1 - 0.03 14.8 0.4 0.051 14.1 0.4 1.8 1 1 0 1 1 1 0 ABC transporter FAD-SLDH PF12318.8 KFP00672.1 - 0.046 13.8 0.2 0.2 11.7 0.1 1.9 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase FeoB_N PF02421.18 KFP00672.1 - 0.049 13.2 0.1 0.16 11.5 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 KFP00672.1 - 0.075 12.4 0.1 0.24 10.8 0.1 2.1 1 1 0 1 1 1 0 Bacterial TniB protein PduV-EutP PF10662.9 KFP00672.1 - 0.087 12.6 0.0 0.25 11.1 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 KFP00672.1 - 0.15 11.9 1.6 0.28 10.9 0.5 1.9 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Vpu PF00558.19 KFP00673.1 - 0.013 15.3 0.4 0.024 14.4 0.4 1.3 1 0 0 1 1 1 0 Vpu protein PRY PF13765.6 KFP00674.1 - 5.3e-21 74.0 0.0 8.2e-21 73.4 0.0 1.3 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.28 KFP00674.1 - 2.7e-06 27.5 0.0 3.4e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 SPRY domain Ran_BP1 PF00638.18 KFP00675.1 - 2e-14 53.9 0.4 7.1e-14 52.1 0.1 1.9 2 0 0 2 2 2 1 RanBP1 domain Lon_C PF05362.13 KFP00676.1 - 1.4e-25 90.1 0.0 4.3e-25 88.4 0.0 1.9 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 KFP00676.1 - 8e-25 87.8 0.0 3.6e-24 85.7 0.0 2.2 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 KFP00676.1 - 5.3e-24 85.3 8.7 5.3e-24 85.3 8.7 2.4 3 1 0 3 3 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA_5 PF07728.14 KFP00676.1 - 4.1e-09 36.5 0.0 1.4e-08 34.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFP00676.1 - 2.9e-08 34.0 0.0 1e-07 32.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KFP00676.1 - 6.4e-07 29.9 2.2 9.2e-06 26.1 0.0 3.2 3 1 1 4 4 3 1 AAA ATPase domain RuvB_N PF05496.12 KFP00676.1 - 6.6e-07 29.2 0.0 1.4e-05 24.9 0.0 2.6 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_PrkA PF08298.11 KFP00676.1 - 3.1e-06 26.3 0.0 6.2e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 KFP00676.1 - 3.6e-05 24.1 1.5 0.0011 19.3 0.0 3.5 3 1 0 3 3 2 1 AAA domain AAA_14 PF13173.6 KFP00676.1 - 0.00071 19.6 0.2 0.0031 17.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFP00676.1 - 0.0015 18.9 0.0 0.0039 17.5 0.0 1.8 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 KFP00676.1 - 0.0018 18.0 0.0 0.005 16.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein LXG PF04740.12 KFP00676.1 - 0.012 15.3 1.9 0.16 11.6 0.4 3.0 3 0 0 3 3 3 0 LXG domain of WXG superfamily RsgA_GTPase PF03193.16 KFP00676.1 - 0.02 14.8 0.2 0.068 13.1 0.0 2.0 2 0 0 2 2 1 0 RsgA GTPase NACHT PF05729.12 KFP00676.1 - 0.022 14.7 0.0 0.1 12.5 0.0 2.3 1 1 0 1 1 1 0 NACHT domain AAA_3 PF07726.11 KFP00676.1 - 0.024 14.5 0.0 0.24 11.3 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KFP00676.1 - 0.024 14.3 0.0 0.072 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFP00676.1 - 0.026 15.0 0.0 0.026 15.0 0.0 2.8 3 1 0 3 3 2 0 AAA domain Acetate_kinase PF00871.17 KFP00676.1 - 0.03 13.0 0.4 0.048 12.4 0.4 1.3 1 0 0 1 1 1 0 Acetokinase family TsaE PF02367.17 KFP00676.1 - 0.034 14.1 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KFP00676.1 - 0.038 14.2 0.1 0.2 11.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFP00676.1 - 0.043 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Peptidase_S41_N PF11918.8 KFP00676.1 - 0.052 13.8 4.7 1.7 8.8 0.0 3.8 4 1 0 4 4 3 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Viral_helicase1 PF01443.18 KFP00676.1 - 0.057 13.2 0.1 0.52 10.0 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KFP00676.1 - 0.061 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFP00676.1 - 0.061 13.8 0.7 0.57 10.7 0.0 2.7 2 1 0 2 2 2 0 ABC transporter Parvo_NS1 PF01057.17 KFP00676.1 - 0.075 12.1 0.0 0.22 10.6 0.0 1.8 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.6 KFP00676.1 - 0.13 12.7 0.0 0.13 12.7 0.0 3.3 2 2 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 KFP00676.1 - 0.5 10.3 11.8 0.62 9.9 0.0 3.8 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 KFP00676.1 - 0.77 10.2 0.0 0.77 10.2 0.0 3.5 3 1 1 4 4 4 0 AAA domain AAA_11 PF13086.6 KFP00676.1 - 1.1 9.0 0.0 1.1 9.0 0.0 2.9 2 1 0 2 2 1 0 AAA domain Lon_C PF05362.13 KFP00677.1 - 1.7e-40 138.8 0.0 1.8e-40 138.7 0.0 1.0 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.6 KFP00677.1 - 8.1e-08 32.1 0.0 1.1e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Ribosomal_L36e PF01158.18 KFP00678.1 - 2.5e-37 127.0 6.3 2.8e-37 126.8 6.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Filament PF00038.21 KFP00679.1 - 2.9e-84 283.3 47.0 3.9e-84 282.9 47.0 1.2 1 0 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 KFP00679.1 - 3e-18 66.2 0.4 6.3e-18 65.2 0.4 1.5 1 0 0 1 1 1 1 Lamin Tail Domain BRE1 PF08647.11 KFP00679.1 - 0.0011 19.0 7.8 0.0011 19.0 7.8 4.3 1 1 3 4 4 3 2 BRE1 E3 ubiquitin ligase FPP PF05911.11 KFP00679.1 - 0.023 12.9 38.1 0.2 9.8 23.2 3.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Spc7 PF08317.11 KFP00679.1 - 0.028 13.3 44.3 0.59 9.0 13.4 2.6 1 1 2 3 3 3 0 Spc7 kinetochore protein PspB PF06667.12 KFP00679.1 - 0.051 13.6 0.7 0.33 11.0 0.7 2.6 1 0 0 1 1 1 0 Phage shock protein B DUF1326 PF07040.11 KFP00679.1 - 0.14 12.2 1.3 0.25 11.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1326) Laminin_II PF06009.12 KFP00679.1 - 0.25 11.4 18.1 0.85 9.6 5.9 2.8 2 1 0 2 2 2 0 Laminin Domain II DUF1844 PF08899.11 KFP00679.1 - 0.31 11.3 10.1 0.47 10.8 0.9 3.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1844) DUF1664 PF07889.12 KFP00679.1 - 1.5 8.8 25.2 8.6 6.4 2.5 5.1 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) PKcGMP_CC PF16808.5 KFP00679.1 - 3.5 7.6 19.4 0.96 9.4 0.1 5.1 3 2 1 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase M PF02370.16 KFP00679.1 - 4.3 8.2 14.6 1.5 9.6 3.3 4.8 3 0 0 3 3 2 0 M protein repeat TPR_MLP1_2 PF07926.12 KFP00679.1 - 5.5 7.1 50.2 39 4.3 16.2 4.9 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein HALZ PF02183.18 KFP00679.1 - 6.7 7.0 14.9 0.52 10.6 1.3 3.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper FlaC_arch PF05377.11 KFP00679.1 - 7.6 7.0 14.8 8 6.9 0.3 4.9 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) zf-Tim10_DDP PF02953.15 KFP00680.1 - 7.1e-22 76.8 1.6 8.2e-22 76.6 1.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Trypsin PF00089.26 KFP00681.1 - 4.8e-65 219.4 0.0 5.4e-65 219.3 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFP00681.1 - 1.9e-08 34.7 0.0 2.9e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin PF00089.26 KFP00682.1 - 7.2e-70 235.2 0.0 8e-70 235.1 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFP00682.1 - 3.1e-05 24.9 0.0 5.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFP00682.1 - 4.1e-05 23.9 0.0 7.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Peptidase_A22B PF04258.13 KFP00683.1 - 3.5e-85 286.0 15.2 4.9e-85 285.5 15.2 1.1 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.22 KFP00683.1 - 1.8e-08 34.3 0.0 4.5e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 PA domain DUF4079 PF13301.6 KFP00683.1 - 0.12 12.5 2.1 0.17 12.0 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) LSM PF01423.22 KFP00684.1 - 2.3e-21 75.3 0.0 2.7e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain Kelch_6 PF13964.6 KFP00685.1 - 3.1e-21 74.8 14.2 2.1e-05 24.6 0.1 6.5 4 2 2 6 6 6 5 Kelch motif BACK PF07707.15 KFP00685.1 - 4.5e-20 71.7 2.6 7.6e-20 70.9 0.6 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_1 PF01344.25 KFP00685.1 - 1.2e-19 69.6 20.5 0.00025 20.6 0.1 7.1 6 1 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KFP00685.1 - 1.3e-08 34.7 7.2 0.035 14.1 0.1 6.1 5 1 1 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP00685.1 - 1.6e-08 34.4 6.6 0.58 10.2 0.1 5.9 7 0 0 7 7 7 3 Kelch motif Kelch_2 PF07646.15 KFP00685.1 - 1.8e-07 30.9 9.6 0.085 12.9 0.1 5.9 5 1 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 KFP00685.1 - 2e-06 27.9 5.8 0.0014 18.9 0.1 5.1 6 0 0 6 6 6 1 Galactose oxidase, central domain BTB PF00651.31 KFP00685.1 - 6.1e-06 26.4 0.1 9.6e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF1668 PF07893.13 KFP00685.1 - 0.097 12.0 0.1 0.79 9.0 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1668) TRAM_LAG1_CLN8 PF03798.16 KFP00686.1 - 2.5e-37 128.6 29.8 3.2e-37 128.2 29.8 1.1 1 0 0 1 1 1 1 TLC domain Homeodomain PF00046.29 KFP00686.1 - 5.1e-07 29.4 0.0 1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 KFP00686.1 - 0.0012 18.2 0.4 0.0033 16.9 0.0 1.8 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 KFP00686.1 - 0.028 14.3 0.1 0.076 12.9 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain Tmemb_9 PF05434.11 KFP00686.1 - 2.2 8.2 4.7 0.37 10.7 0.1 1.9 1 1 1 2 2 2 0 TMEM9 SEA PF01390.20 KFP00687.1 - 4.7e-103 338.5 13.1 7.4e-24 83.9 0.0 5.3 5 0 0 5 5 5 5 SEA domain DUF2205 PF10224.9 KFP00687.1 - 2.1e-05 24.4 0.0 0.91 9.6 0.0 3.5 3 0 0 3 3 3 2 Short coiled-coil protein DUF4488 PF14869.6 KFP00687.1 - 0.0071 16.2 1.9 3 7.8 0.0 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF4488) SH3_10 PF17902.1 KFP00687.1 - 0.0077 16.3 0.0 2.6 8.2 0.0 2.9 3 0 0 3 3 3 1 SH3 domain Afaf PF15339.6 KFP00687.1 - 0.0081 15.9 0.6 0.025 14.3 0.1 2.1 2 0 0 2 2 2 1 Acrosome formation-associated factor Epiglycanin_C PF14654.6 KFP00687.1 - 0.011 15.8 0.2 0.025 14.7 0.2 1.6 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region UPF0560 PF10577.9 KFP00687.1 - 0.077 11.5 0.6 0.12 10.8 0.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 RRM_1 PF00076.22 KFP00688.1 - 1.4e-20 72.9 0.0 4.9e-10 39.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop10p PF04135.12 KFP00689.1 - 1.5e-21 76.2 0.3 1.7e-21 76.0 0.3 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family zf-RING_11 PF17123.5 KFP00690.1 - 3.1e-09 36.4 2.7 6e-09 35.5 2.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KFP00690.1 - 1.6e-05 25.2 2.6 2.8e-05 24.3 2.6 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_1 PF14446.6 KFP00690.1 - 0.0016 18.3 1.6 0.0026 17.6 1.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-C3HC4 PF00097.25 KFP00690.1 - 0.0035 17.2 2.8 0.0068 16.3 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP00690.1 - 0.0049 16.7 2.2 0.0097 15.7 2.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP00690.1 - 0.0097 15.9 2.7 0.017 15.2 2.7 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP00690.1 - 0.017 15.1 2.1 0.028 14.4 2.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Orthoreo_P10 PF07204.11 KFP00690.1 - 0.027 14.4 0.6 0.039 13.9 0.6 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 LapA_dom PF06305.11 KFP00690.1 - 0.13 12.1 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Fumble PF03630.14 KFP00691.1 - 1.7e-117 392.3 0.0 1.9e-117 392.1 0.0 1.0 1 0 0 1 1 1 1 Fumble CARD_2 PF16739.5 KFP00692.1 - 9.9e-14 51.1 0.1 1.6e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Caspase recruitment domain Y_phosphatase PF00102.27 KFP00693.1 - 7.9e-54 182.7 2.6 1.1e-53 182.3 2.6 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase RIFIN PF02009.16 KFP00693.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Rifin Orf78 PF06024.12 KFP00693.1 - 0.044 14.1 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) EphA2_TM PF14575.6 KFP00693.1 - 0.13 13.2 0.0 0.29 12.0 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2207 PF09972.9 KFP00693.1 - 0.16 10.7 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3149 PF11346.8 KFP00693.1 - 0.19 11.4 2.0 0.45 10.2 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) TMEM154 PF15102.6 KFP00693.1 - 0.24 11.3 8.7 1.6 8.6 8.7 2.2 1 1 0 1 1 1 0 TMEM154 protein family RVT_thumb PF06817.14 KFP00694.1 - 5.1e-24 83.9 1.4 5.1e-24 83.9 1.4 1.8 1 1 1 2 2 2 1 Reverse transcriptase thumb domain RVT_1 PF00078.27 KFP00694.1 - 2e-17 63.5 0.0 3.3e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PGK PF00162.19 KFP00696.1 - 1.8e-142 474.8 0.9 2e-142 474.6 0.9 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Yae1_N PF09811.9 KFP00697.1 - 6.7e-18 64.1 47.2 1.8e+04 -13.7 47.2 5.6 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Ion_trans PF00520.31 KFP00698.1 - 6.3e-31 107.5 11.4 9.7e-31 106.9 11.4 1.2 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.11 KFP00698.1 - 8.8e-29 99.5 0.3 1.9e-28 98.5 0.3 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.7 KFP00698.1 - 9.8e-11 42.1 1.2 2.5e-06 28.0 0.4 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP00698.1 - 1.6e-07 31.8 0.0 0.015 15.9 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP00698.1 - 1.1e-05 25.4 5.0 0.23 12.1 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 KFP00698.1 - 0.00017 21.9 1.6 0.099 13.1 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KFP00698.1 - 0.00043 20.5 0.4 1.1 9.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) PKD_channel PF08016.12 KFP00698.1 - 0.00048 18.9 14.2 0.019 13.7 14.2 2.7 1 1 0 1 1 1 1 Polycystin cation channel Gp-FAR-1 PF05823.12 KFP00698.1 - 0.12 12.7 12.4 1.1 9.7 1.1 3.4 3 0 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Glyco_tran_28_C PF04101.16 KFP00699.1 - 2.3e-20 73.3 0.0 2.4e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DCX PF03607.17 KFP00700.1 - 2.3e-43 146.1 0.1 4e-22 78.1 0.0 2.4 2 0 0 2 2 2 2 Doublecortin MGC-24 PF05283.11 KFP00700.1 - 0.14 12.6 4.3 0.2 12.1 0.9 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF2457 PF10446.9 KFP00700.1 - 3.5 6.7 10.8 0.22 10.6 5.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Yae1_N PF09811.9 KFP00701.1 - 0.022 14.5 43.9 2.4 7.9 2.4 5.3 1 1 3 4 4 4 0 Essential protein Yae1, N terminal Pkinase PF00069.25 KFP00702.1 - 1e-72 244.7 0.0 1.5e-72 244.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP00702.1 - 1.6e-45 155.4 0.0 2.5e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KFP00702.1 - 1.1e-23 83.3 0.0 3.3e-23 81.8 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KFP00702.1 - 1.5e-07 31.0 0.2 0.00034 20.0 0.0 2.7 2 1 1 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 KFP00702.1 - 1.5e-06 27.2 0.4 3.9e-06 25.9 0.4 1.8 1 1 0 1 1 1 1 Fungal protein kinase Spt5_N PF11942.8 KFP00702.1 - 0.00096 20.1 2.3 0.0022 18.9 2.3 1.6 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal APH PF01636.23 KFP00702.1 - 0.0057 16.6 0.1 0.069 13.1 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family DSHCT PF08148.12 KFP00702.1 - 0.014 15.1 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 DSHCT (NUC185) domain Kdo PF06293.14 KFP00702.1 - 0.058 12.8 0.0 0.13 11.6 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SOG2 PF10428.9 KFP00702.1 - 1.9 7.6 7.9 3 6.9 7.9 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Med13_C PF06333.12 KFP00702.1 - 2.9 7.1 8.8 7.6 5.7 8.9 1.7 1 1 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain VWC PF00093.18 KFP00703.1 - 2.3e-26 91.9 61.0 1.2e-09 38.4 10.2 3.8 4 0 0 4 4 4 3 von Willebrand factor type C domain Amnionless PF14828.6 KFP00703.1 - 3.3e-05 22.9 4.0 3.3e-05 22.9 4.0 3.1 1 1 2 3 3 3 3 Amnionless DUF1496 PF07383.12 KFP00703.1 - 0.0089 15.6 2.5 2 8.1 0.0 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1496) AMMECR1 PF01871.17 KFP00704.1 - 2.5e-47 160.6 0.0 2.9e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 TMEM164 PF14808.6 KFP00705.1 - 8.2e-118 392.3 9.4 9.5e-118 392.1 9.4 1.0 1 0 0 1 1 1 1 TMEM164 family DUF1184 PF06683.11 KFP00705.1 - 0.18 11.3 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) AMP-binding PF00501.28 KFP00706.1 - 4.1e-108 361.7 0.0 5.4e-108 361.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFP00706.1 - 5.9e-07 30.4 0.0 6.2e-05 23.9 0.0 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ISK_Channel PF02060.15 KFP00707.1 - 2.2e-13 50.0 0.0 2.6e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 Slow voltage-gated potassium channel NTF2 PF02136.20 KFP00708.1 - 5.6e-31 107.6 0.5 6.5e-31 107.4 0.5 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_2 PF12680.7 KFP00708.1 - 0.046 14.4 0.0 0.055 14.1 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain C4 PF01413.19 KFP00709.1 - 5e-67 223.3 6.0 9e-46 154.8 0.5 2.0 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Peptidase_C54 PF03416.19 KFP00710.1 - 3.8e-103 344.7 0.1 4.5e-103 344.4 0.1 1.1 1 0 0 1 1 1 1 Peptidase family C54 Ank_5 PF13857.6 KFP00711.1 - 2.2e-49 164.8 9.2 2.3e-10 40.5 0.2 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP00711.1 - 5.7e-46 154.3 5.1 4.8e-12 46.2 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP00711.1 - 3e-45 152.7 2.0 7.6e-16 58.5 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFP00711.1 - 2.7e-40 135.1 4.8 7.5e-09 35.7 0.1 5.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 KFP00711.1 - 7.1e-39 127.4 0.9 1.2e-07 31.5 0.0 5.2 5 0 0 5 5 5 5 Ankyrin repeat DUF249 PF03158.13 KFP00711.1 - 0.059 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Multigene family 530 protein DUF4799 PF16056.5 KFP00711.1 - 0.14 11.3 0.1 0.29 10.2 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4799) Ras PF00071.22 KFP00712.1 - 1.3e-29 102.9 0.1 1.6e-29 102.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP00712.1 - 7e-06 26.3 0.0 1.2e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase CENP-M PF11111.8 KFP00712.1 - 0.018 14.3 0.0 0.023 13.9 0.0 1.1 1 0 0 1 1 1 0 Centromere protein M (CENP-M) VGCC_beta4Aa_N PF12052.8 KFP00712.1 - 0.15 12.2 0.1 0.3 11.2 0.1 1.5 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Prefoldin PF02996.17 KFP00713.1 - 5.1e-37 126.4 0.3 7.8e-37 125.8 0.3 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KFP00713.1 - 0.00022 21.1 4.8 0.024 14.6 0.0 2.3 2 1 0 2 2 2 2 Prefoldin subunit ATG19_autophagy PF12744.7 KFP00713.1 - 0.057 12.6 1.2 0.086 12.0 1.2 1.2 1 0 0 1 1 1 0 Autophagy protein Atg19, Atg8-binding HR1 PF02185.16 KFP00713.1 - 0.27 11.4 0.2 0.27 11.4 0.2 2.9 3 1 0 3 3 3 0 Hr1 repeat ANTH PF07651.16 KFP00714.1 - 2e-70 236.9 1.4 3.5e-70 236.2 1.4 1.4 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KFP00714.1 - 4.1e-07 30.1 0.1 1.1e-06 28.8 0.1 1.7 1 0 0 1 1 1 1 ENTH domain SNF2_N PF00176.23 KFP00715.1 - 4.4e-80 269.0 0.4 1e-79 267.8 0.4 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KFP00715.1 - 2.2e-42 143.7 3.6 2.2e-42 143.7 3.6 2.7 3 0 0 3 3 3 1 SLIDE HAND PF09110.11 KFP00715.1 - 6.3e-30 104.2 2.2 6.3e-30 104.2 2.2 3.4 3 0 0 3 3 2 1 HAND Helicase_C PF00271.31 KFP00715.1 - 1e-21 77.4 0.0 1.2e-20 74.0 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP00715.1 - 9e-12 45.3 0.0 9.6e-11 42.0 0.0 2.8 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFP00715.1 - 4.4e-07 29.8 0.0 2.2e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KFP00715.1 - 2.4e-05 23.7 0.0 6.2e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Myb_DNA-binding PF00249.31 KFP00715.1 - 2.8e-05 24.2 0.1 0.44 10.8 0.0 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain DBINO PF13892.6 KFP00715.1 - 2.9e-05 24.4 0.3 2.9e-05 24.4 0.3 5.2 5 0 0 5 5 5 1 DNA-binding domain ERCC3_RAD25_C PF16203.5 KFP00715.1 - 0.0022 17.2 0.0 0.0069 15.6 0.0 1.8 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF1086 PF06461.11 KFP00715.1 - 0.0059 16.5 0.1 0.054 13.4 0.1 2.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1086) UBA_2 PF08587.11 KFP00715.1 - 0.15 12.2 1.7 0.8 9.9 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin associated domain (UBA) Yae1_N PF09811.9 KFP00716.1 - 1.8e-12 46.7 48.0 1.8e+04 -13.7 48.0 5.5 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Tox-GHH PF15636.6 KFP00717.1 - 2.2e-29 101.2 0.9 4.4e-29 100.3 0.9 1.5 1 0 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin Ten_N PF06484.12 KFP00717.1 - 2.8e-23 83.4 8.9 4.2e-23 82.9 8.9 1.3 1 0 0 1 1 1 1 Teneurin Intracellular Region EGF_2 PF07974.13 KFP00717.1 - 5.3e-20 71.5 152.9 0.00037 20.8 9.4 9.7 8 1 1 9 9 9 7 EGF-like domain RHS_repeat PF05593.14 KFP00717.1 - 5.9e-11 42.6 25.2 0.00045 20.6 0.8 8.3 7 1 1 8 8 8 4 RHS Repeat NHL PF01436.21 KFP00717.1 - 9.1e-07 28.6 0.8 0.43 10.7 0.0 6.0 5 0 0 5 5 5 1 NHL repeat SGL PF08450.12 KFP00717.1 - 0.00041 20.0 0.1 0.52 9.8 0.0 3.6 3 1 1 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region CarboxypepD_reg PF13620.6 KFP00717.1 - 0.0039 17.4 0.3 0.013 15.8 0.3 1.9 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain I-EGF_1 PF18372.1 KFP00717.1 - 0.013 15.6 0.9 0.013 15.6 0.9 9.6 10 0 0 10 10 9 0 Integrin beta epidermal growth factor like domain 1 DUF1939 PF09154.10 KFP00717.1 - 0.059 13.5 0.2 0.21 11.8 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) RHS PF03527.14 KFP00717.1 - 0.1 12.3 1.8 0.21 11.4 0.0 2.5 3 0 0 3 3 3 0 RHS protein FlaE PF07559.14 KFP00717.1 - 7.3 7.2 6.2 37 4.9 0.2 4.3 4 1 0 4 4 4 0 Flagellar basal body protein FlaE SH2 PF00017.24 KFP00718.1 - 6.6e-14 51.8 0.0 8.3e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 SH2 domain STAG PF08514.11 KFP00719.1 - 1.8e-37 127.7 0.1 9.2e-37 125.4 0.1 2.3 1 0 0 1 1 1 1 STAG domain Cnd3 PF12719.7 KFP00719.1 - 0.0047 16.2 0.4 0.025 13.8 0.4 2.3 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain AdoHcyase_NAD PF00670.21 KFP00719.1 - 0.052 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Tho2 PF11262.8 KFP00720.1 - 3.7e-104 348.2 2.3 3.7e-104 348.2 2.3 4.7 4 2 1 5 5 5 1 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 KFP00720.1 - 4e-83 280.2 6.3 3.7e-57 194.4 3.1 4.9 3 2 1 4 4 4 2 THO complex subunit 2 N-terminus Thoc2 PF11732.8 KFP00720.1 - 3.5e-37 126.3 0.9 3.1e-36 123.3 0.2 2.8 3 0 0 3 3 3 1 Transcription- and export-related complex subunit ANF_receptor PF01094.28 KFP00721.1 - 3.3e-61 207.4 1.0 4.7e-61 206.8 1.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 KFP00721.1 - 4.9e-59 198.5 0.0 8.9e-59 197.6 0.0 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFP00721.1 - 1.1e-45 154.5 0.0 2.3e-45 153.5 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFP00721.1 - 2.3e-24 86.1 0.0 4.2e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF2061 PF09834.9 KFP00721.1 - 0.085 13.4 0.7 0.27 11.8 0.2 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2061) NusG_add PF18298.1 KFP00721.1 - 0.089 13.0 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 NusG additional domain Pre-PUA PF17832.1 KFP00723.1 - 1.2e-25 90.0 0.1 1.7e-25 89.5 0.1 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KFP00723.1 - 3.5e-21 74.9 0.1 6.1e-21 74.2 0.1 1.4 1 0 0 1 1 1 1 PUA domain Methyltr_RsmF_N PF17125.5 KFP00723.1 - 0.054 14.0 0.0 0.08 13.4 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF DUF1947 PF09183.10 KFP00723.1 - 0.071 13.4 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) Cullin PF00888.22 KFP00724.1 - 2.7e-212 706.7 18.4 4.3e-212 706.1 18.4 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KFP00724.1 - 1.3e-25 89.2 1.6 5.5e-25 87.2 1.6 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain SecA_SW PF07516.13 KFP00724.1 - 2.6e-05 24.4 0.2 2.6e-05 24.4 0.2 3.2 3 1 0 3 3 3 1 SecA Wing and Scaffold domain PG_binding_4 PF12229.8 KFP00724.1 - 0.35 11.2 2.5 2 8.7 0.1 3.2 3 0 0 3 3 3 0 Putative peptidoglycan binding domain Lamp PF01299.17 KFP00725.1 - 1.7e-45 154.5 12.2 7.7e-39 132.9 2.9 2.3 2 1 0 2 2 2 2 Lysosome-associated membrane glycoprotein (Lamp) ATP-synt_S1 PF05827.12 KFP00725.1 - 0.00014 21.7 1.3 0.00038 20.3 1.3 1.7 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) DUF4620 PF15399.6 KFP00725.1 - 0.047 14.1 0.7 0.089 13.1 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4620) Na_K-ATPase PF00287.18 KFP00726.1 - 4e-96 321.5 0.2 4.7e-96 321.3 0.2 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain FAM70 PF14967.6 KFP00727.1 - 1.1e-155 518.2 5.0 1.2e-155 518.0 5.0 1.0 1 0 0 1 1 1 1 FAM70 protein DUF4064 PF13273.6 KFP00727.1 - 0.00018 21.7 10.7 0.03 14.6 8.7 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF4064) Phage_holin_3_2 PF04550.12 KFP00727.1 - 0.054 14.0 1.0 0.054 14.0 1.0 2.0 2 0 0 2 2 2 0 Phage holin family 2 DUF2407_C PF13373.6 KFP00727.1 - 1.5 9.0 2.4 3.1 8.0 0.6 2.1 2 0 0 2 2 2 0 DUF2407 C-terminal domain BTB PF00651.31 KFP00728.1 - 3.7e-20 72.2 0.0 6.6e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFP00728.1 - 2.9e-06 27.5 9.9 0.00021 21.6 1.9 3.3 4 0 0 4 4 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP00728.1 - 6.9e-06 26.5 15.7 0.029 15.2 2.2 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KFP00728.1 - 0.0014 19.3 5.5 0.033 14.9 0.3 3.3 1 1 2 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-C2H2 PF00096.26 KFP00728.1 - 0.022 15.2 16.2 0.43 11.1 0.3 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFP00728.1 - 0.024 14.6 14.4 2.6 8.1 0.4 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFP00728.1 - 0.08 12.7 7.9 0.48 10.2 3.0 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type Zn_Tnp_IS1595 PF12760.7 KFP00728.1 - 0.25 11.3 4.0 0.57 10.2 4.0 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C2H2_2 PF12756.7 KFP00728.1 - 4.9 7.6 8.2 73 3.8 0.4 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) C1_1 PF00130.22 KFP00728.1 - 5.1 7.1 6.6 1.2 9.1 2.8 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PyrI_C PF02748.15 KFP00728.1 - 5.7 6.9 6.8 1.1 9.2 1.1 2.4 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn_ribbon_SprT PF17283.2 KFP00728.1 - 7.2 6.6 14.0 2.3 8.2 9.0 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-C2H2_jaz PF12171.8 KFP00728.1 - 9.5 6.6 13.4 6 7.3 0.3 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Nkap_C PF06047.11 KFP00729.1 - 5e-50 167.9 2.0 5e-50 167.9 2.0 3.0 2 1 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain NKAP PF15692.5 KFP00729.1 - 1.4e-13 51.3 14.7 1.4e-13 51.3 14.7 3.9 2 1 2 4 4 4 1 NF-kappa-B-activating protein Ndc1_Nup PF09531.10 KFP00729.1 - 0.37 9.4 11.7 0.42 9.3 11.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOBP PF15279.6 KFP00729.1 - 0.39 11.3 17.2 0.72 10.4 17.2 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein AKAP28 PF14469.6 KFP00730.1 - 7.7e-53 177.4 2.7 8.6e-53 177.2 2.7 1.0 1 0 0 1 1 1 1 28 kDa A-kinase anchor Smg4_UPF3 PF03467.15 KFP00731.1 - 9.9e-38 129.9 5.0 9.9e-38 129.9 5.0 5.2 1 1 2 3 3 3 1 Smg-4/UPF3 family Ribosomal_L39 PF00832.20 KFP00732.1 - 3.6e-24 84.1 11.0 4.1e-24 83.9 11.0 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Septin PF00735.18 KFP00733.1 - 9.6e-96 320.4 0.8 9.6e-96 320.4 0.8 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KFP00733.1 - 6.3e-05 23.0 1.1 0.00011 22.2 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 KFP00733.1 - 0.0019 18.4 0.0 0.0054 16.9 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KFP00733.1 - 0.0021 18.5 0.3 0.019 15.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFP00733.1 - 0.0022 18.3 1.1 0.0055 17.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 KFP00733.1 - 0.0028 17.2 3.2 1.2 8.7 0.0 3.2 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain Atg14 PF10186.9 KFP00733.1 - 0.014 14.5 12.6 0.026 13.6 12.6 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_29 PF13555.6 KFP00733.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Fzo_mitofusin PF04799.13 KFP00733.1 - 0.041 13.4 7.5 0.11 12.1 7.5 1.7 1 0 0 1 1 1 0 fzo-like conserved region AAA_7 PF12775.7 KFP00733.1 - 0.056 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region IMD PF08397.11 KFP00733.1 - 0.059 12.7 13.7 0.12 11.8 13.7 1.4 1 0 0 1 1 1 0 IRSp53/MIM homology domain DUF1890 PF09001.11 KFP00733.1 - 0.1 13.0 0.2 0.25 11.7 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1890) Glucan_synthase PF02364.15 KFP00733.1 - 0.13 10.4 0.0 0.13 10.4 0.0 1.8 2 0 0 2 2 2 0 1,3-beta-glucan synthase component FtsK_SpoIIIE PF01580.18 KFP00733.1 - 0.4 10.0 2.9 4 6.7 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 KFP00733.1 - 0.72 9.7 0.0 0.72 9.7 0.0 3.0 3 1 1 4 4 4 0 RsgA GTPase DUF87 PF01935.17 KFP00733.1 - 0.74 9.9 7.6 3 7.9 0.0 2.6 3 0 0 3 3 3 0 Helicase HerA, central domain Exonuc_VII_L PF02601.15 KFP00733.1 - 0.84 9.1 10.0 1.2 8.6 10.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Dynamin_N PF00350.23 KFP00733.1 - 3.1 7.8 6.7 25 4.9 0.1 2.6 2 1 0 2 2 2 0 Dynamin family ABC_tran PF00005.27 KFP00733.1 - 3.3 8.2 6.2 0.46 11.0 0.2 2.4 2 2 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 KFP00733.1 - 6.7 7.2 25.8 4.2e+03 -2.0 25.8 2.5 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KFP00733.1 - 8.5 6.1 10.1 14 5.3 10.1 1.3 1 0 0 1 1 1 0 AAA domain R3H PF01424.22 KFP00734.1 - 5.5e-13 48.7 0.4 1.7e-12 47.1 0.4 1.9 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 KFP00734.1 - 4e-12 45.8 2.6 4e-12 45.8 2.6 2.1 2 0 0 2 2 2 1 G-patch domain dsrm PF00035.26 KFP00734.1 - 1.2e-10 41.9 5.5 0.0002 22.0 0.1 4.2 4 0 0 4 4 4 2 Double-stranded RNA binding motif G-patch_2 PF12656.7 KFP00734.1 - 7.6e-05 22.7 1.2 0.00029 20.9 1.2 2.1 1 0 0 1 1 1 1 G-patch domain S8_pro-domain PF16470.5 KFP00734.1 - 0.029 15.2 2.1 0.11 13.3 0.5 2.7 2 0 0 2 2 2 0 Peptidase S8 pro-domain UQ_con PF00179.26 KFP00735.1 - 1.5e-40 138.1 0.1 1.6e-40 138.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFP00735.1 - 0.00011 22.4 0.1 0.00014 22.2 0.1 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KFP00735.1 - 0.0081 15.9 0.0 0.0096 15.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KFP00735.1 - 0.0098 15.7 0.1 0.015 15.1 0.1 1.3 1 0 0 1 1 1 1 UEV domain DUF5487 PF17589.2 KFP00735.1 - 0.045 14.0 0.0 0.077 13.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5487) DUF2121 PF09894.9 KFP00735.1 - 0.16 11.5 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) Mito_carr PF00153.27 KFP00736.1 - 7.3e-57 189.3 1.9 2.8e-23 81.6 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 KFP00736.1 - 0.021 14.0 0.1 0.12 11.5 0.1 1.9 2 0 0 2 2 2 0 Fuseless Mito_carr PF00153.27 KFP00737.1 - 4e-50 167.7 0.2 1.7e-25 88.8 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Serine_protease PF18405.1 KFP00737.1 - 0.00043 19.5 0.5 0.011 14.9 0.0 2.6 2 1 1 3 3 3 1 Gammaproteobacterial serine protease Cyt-b5 PF00173.28 KFP00738.1 - 7e-13 48.5 0.0 1e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain LON_substr_bdg PF02190.16 KFP00740.1 - 2e-20 73.6 0.0 2.5e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KFP00740.1 - 5.4e-09 35.8 9.0 1.7e-08 34.1 9.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP00740.1 - 1.3e-06 28.2 7.7 1.3e-06 28.2 7.7 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP00740.1 - 1.4e-06 28.1 7.8 3.7e-06 26.7 7.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP00740.1 - 1.6e-06 27.9 6.6 4.8e-06 26.4 6.6 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFP00740.1 - 2e-06 28.1 8.3 2e-06 28.1 8.3 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KFP00740.1 - 9.6e-06 25.7 5.7 3e-05 24.1 5.7 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KFP00740.1 - 3e-05 24.0 7.8 3e-05 24.0 7.8 2.6 2 1 1 3 3 3 1 RING-type zinc-finger zf-rbx1 PF12678.7 KFP00740.1 - 0.00011 22.4 7.0 0.00037 20.7 7.0 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFP00740.1 - 0.00033 20.5 8.7 0.00033 20.5 8.7 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KFP00740.1 - 0.0067 16.2 5.2 0.0067 16.2 5.2 2.0 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain U-box PF04564.15 KFP00740.1 - 0.082 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 U-box domain COMM_domain PF07258.14 KFP00741.1 - 4.4e-17 62.0 0.0 9.7e-17 60.9 0.0 1.6 1 0 0 1 1 1 1 COMM domain HOCHOB PF17943.1 KFP00741.1 - 0.14 12.9 0.0 0.7 10.6 0.0 1.9 2 0 0 2 2 2 0 Homeobox-cysteine loop-homeobox FAM199X PF15814.5 KFP00742.1 - 9.3e-206 682.2 21.9 1e-205 682.0 21.9 1.0 1 0 0 1 1 1 1 Protein family FAM199X Macoilin PF09726.9 KFP00742.1 - 0.053 12.1 11.7 0.064 11.8 11.7 1.1 1 0 0 1 1 1 0 Macoilin family TIR PF01582.20 KFP00743.1 - 7.7e-31 107.2 0.1 1.9e-30 105.9 0.1 1.6 1 0 0 1 1 1 1 TIR domain Ig_2 PF13895.6 KFP00743.1 - 1.6e-21 76.4 0.0 4.3e-08 33.4 0.1 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Ig_6 PF18452.1 KFP00743.1 - 2.1e-21 75.2 0.0 5.2e-15 54.7 0.1 3.4 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFP00743.1 - 4.4e-21 74.8 0.1 6.2e-06 26.2 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP00743.1 - 7.2e-20 71.4 0.0 3.4e-06 27.6 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFP00743.1 - 8.1e-18 64.4 0.1 8.8e-06 25.8 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFP00743.1 - 5.1e-11 42.7 0.1 0.2 11.8 0.0 5.0 3 3 0 3 3 3 3 Immunoglobulin V-set domain TIR_2 PF13676.6 KFP00743.1 - 1.4e-06 28.9 0.0 2.9e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 TIR domain Izumo-Ig PF16706.5 KFP00743.1 - 5.4e-05 23.2 0.2 0.17 11.9 0.0 3.5 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain V-set_CD47 PF08204.11 KFP00743.1 - 0.00031 20.7 2.3 0.087 12.8 0.1 3.5 4 0 0 4 4 4 1 CD47 immunoglobulin-like domain Herpes_gE PF02480.16 KFP00743.1 - 0.035 12.9 0.0 1.1 7.9 0.0 2.5 2 1 0 2 2 2 0 Alphaherpesvirus glycoprotein E Pkinase PF00069.25 KFP00744.1 - 2.1e-54 184.7 0.0 3.7e-54 183.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain CNH PF00780.22 KFP00744.1 - 6.8e-54 183.3 0.0 1.2e-53 182.5 0.0 1.4 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.17 KFP00744.1 - 8.7e-41 139.9 0.0 1.4e-40 139.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP00744.1 - 0.00094 18.6 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFP00744.1 - 0.32 10.9 0.1 0.32 10.9 0.1 2.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF5521 PF17659.1 KFP00745.1 - 5.5e-239 795.4 0.2 6.3e-239 795.2 0.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5521) DUF5088 PF17008.5 KFP00745.1 - 0.0023 17.7 0.0 0.0079 15.9 0.0 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF5088) tRNA_anti-codon PF01336.25 KFP00745.1 - 0.015 15.2 0.0 0.1 12.6 0.0 2.2 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Acyltransf_C PF16076.5 KFP00745.1 - 0.02 15.0 0.5 0.26 11.4 0.5 2.8 1 1 0 1 1 1 0 Acyltransferase C-terminus DUF4460 PF14687.6 KFP00745.1 - 0.046 13.8 0.2 0.87 9.7 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4460) zf-RING_2 PF13639.6 KFP00746.1 - 1.2e-11 44.8 7.9 1.9e-11 44.1 7.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFP00746.1 - 1.5e-08 34.8 5.8 3e-08 33.8 5.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KFP00746.1 - 4.1e-08 32.8 3.5 8.2e-08 31.9 3.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFP00746.1 - 6.1e-08 32.4 7.8 1e-07 31.7 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP00746.1 - 3.5e-07 30.0 7.9 5.6e-07 29.3 7.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 KFP00746.1 - 4.5e-07 29.8 0.0 9.4e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 KFP00746.1 - 3e-06 27.1 8.8 4.9e-06 26.4 8.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFP00746.1 - 3.3e-05 23.8 5.0 5.9e-05 23.0 5.0 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFP00746.1 - 0.00018 21.3 7.3 0.00026 20.8 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP00746.1 - 0.0006 19.6 9.2 0.001 18.9 9.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFP00746.1 - 0.007 16.4 3.4 0.013 15.5 3.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_16 PF17034.5 KFP00746.1 - 0.025 14.8 2.1 0.05 13.8 2.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon like family zf-C3H2C3 PF17122.5 KFP00746.1 - 0.038 14.0 2.6 0.083 12.9 2.6 1.6 1 0 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 KFP00746.1 - 0.047 13.3 6.4 0.085 12.5 6.4 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 KFP00746.1 - 0.53 10.2 8.1 0.93 9.4 8.1 1.4 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 KFP00746.1 - 0.73 10.0 4.6 1.7 8.8 4.6 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger RabGAP-TBC PF00566.18 KFP00747.1 - 4.7e-44 150.6 0.0 4.7e-44 150.6 0.0 2.2 3 0 0 3 3 3 1 Rab-GTPase-TBC domain GRAM PF02893.20 KFP00747.1 - 3.2e-33 114.0 1.4 5e-19 68.3 0.2 2.5 2 0 0 2 2 2 2 GRAM domain EF-hand_1 PF00036.32 KFP00747.1 - 0.14 11.7 0.3 0.74 9.5 0.0 2.5 2 0 0 2 2 2 0 EF hand HLH PF00010.26 KFP00748.1 - 9.1e-11 41.6 0.8 1.8e-10 40.6 0.8 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS PF00989.25 KFP00748.1 - 2.9e-10 40.1 0.0 4.6e-08 33.0 0.0 3.4 3 0 0 3 3 3 1 PAS fold PAS_3 PF08447.12 KFP00748.1 - 2.4e-07 30.9 0.0 0.0026 18.0 0.0 3.0 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.6 KFP00748.1 - 9.6e-07 28.9 0.0 0.0002 21.5 0.0 2.9 2 0 0 2 2 2 1 PAS domain PAS_9 PF13426.7 KFP00748.1 - 0.00026 21.2 0.0 0.00099 19.3 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 KFP00748.1 - 0.15 12.3 0.1 0.75 10.1 0.0 2.3 2 0 0 2 2 2 0 PAS fold Meis_PKNOX_N PF16493.5 KFP00748.1 - 0.31 11.4 3.1 8.7 6.8 0.1 3.4 3 0 0 3 3 3 0 N-terminal of Homeobox Meis and PKNOX1 DDRGK PF09756.9 KFP00748.1 - 0.71 9.4 7.4 0.14 11.7 1.2 2.1 2 0 0 2 2 2 0 DDRGK domain VMA21 PF09446.10 KFP00749.1 - 4.6e-21 74.7 7.9 5.2e-21 74.5 7.9 1.0 1 0 0 1 1 1 1 VMA21-like domain TctB PF07331.11 KFP00749.1 - 0.065 13.5 4.4 0.079 13.2 4.4 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family 7tm_7 PF08395.12 KFP00749.1 - 0.11 11.7 2.1 0.11 11.6 2.1 1.0 1 0 0 1 1 1 0 7tm Chemosensory receptor 7tm_1 PF00001.21 KFP00750.1 - 1.1e-52 179.0 24.3 1.1e-52 179.0 24.3 1.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP00750.1 - 8.6e-08 31.9 26.4 1.2e-07 31.4 26.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Serpentine_r_xa PF03383.15 KFP00750.1 - 0.1 12.6 17.1 0.025 14.5 2.3 2.7 1 1 1 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa 7TM_GPCR_Srx PF10328.9 KFP00750.1 - 0.52 9.9 34.5 1.4 8.5 32.4 2.3 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 KFP00751.1 - 2.9e-35 121.9 19.8 4.2e-35 121.3 19.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 KFP00752.1 - 9.5e-40 136.6 14.5 1.2e-39 136.2 14.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFP00752.1 - 0.0036 16.7 14.2 0.059 12.6 0.4 2.3 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 KFP00753.1 - 4.8e-40 137.5 16.7 5.7e-40 137.3 16.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFP00753.1 - 0.00011 21.6 0.5 0.00011 21.6 0.5 2.6 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw BRICHOS PF04089.14 KFP00754.1 - 1.3e-18 67.0 0.0 2.9e-18 65.9 0.0 1.6 2 0 0 2 2 2 1 BRICHOS domain T-box PF00907.22 KFP00755.1 - 9.3e-79 264.0 0.1 1e-78 263.8 0.1 1.0 1 0 0 1 1 1 1 T-box LIG3_BRCT PF16759.5 KFP00755.1 - 0.11 12.7 0.1 2.1 8.7 0.0 2.4 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain Snf7 PF03357.21 KFP00756.1 - 3.7e-16 59.2 17.7 4.4e-16 59.0 17.7 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 KFP00756.1 - 3.2e-05 23.9 7.6 4.4e-05 23.5 7.6 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway FlxA PF14282.6 KFP00756.1 - 0.037 14.0 7.4 0.04 13.9 0.8 2.2 2 0 0 2 2 2 0 FlxA-like protein Mu-like_Pro PF10123.9 KFP00756.1 - 0.047 13.2 9.1 0.059 12.9 9.1 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein DMSP_lyase PF16867.5 KFP00756.1 - 0.11 12.1 0.2 0.18 11.4 0.2 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase DUF948 PF06103.11 KFP00756.1 - 0.16 12.3 8.8 0.054 13.7 4.9 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Mt_ATP-synt_D PF05873.12 KFP00756.1 - 0.23 11.3 10.1 0.4 10.5 0.6 2.6 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) GrpE PF01025.19 KFP00756.1 - 0.64 9.7 10.6 1.1 8.9 10.5 1.4 1 1 0 1 1 1 0 GrpE NTP_transf_7 PF07984.12 KFP00757.1 - 4.1e-158 525.7 3.2 4.7e-158 525.5 3.2 1.0 1 0 0 1 1 1 1 Nucleotidyltransferase HMG14_17 PF01101.18 KFP00758.1 - 1.7e-20 73.7 38.1 3.5e-20 72.8 38.1 1.5 1 1 0 1 1 1 1 HMG14 and HMG17 Pap_E4 PF02711.14 KFP00758.1 - 2.8 9.0 11.0 7.8 7.5 11.0 1.7 1 1 0 1 1 1 0 E4 protein BORG_CEP PF14957.6 KFP00758.1 - 5.3 8.2 11.7 6 8.0 11.7 1.1 1 0 0 1 1 1 0 Cdc42 effector SH3BGR PF04908.15 KFP00759.1 - 2.1e-36 124.0 0.1 2.5e-36 123.8 0.1 1.1 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 KFP00759.1 - 0.00036 20.7 0.0 0.00055 20.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF4569 PF15133.6 KFP00760.1 - 1e-94 317.6 0.3 1.2e-94 317.5 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4569) Na_H_Exchanger PF00999.21 KFP00761.1 - 4e-84 282.6 36.4 4.7e-84 282.4 36.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NEXCaM_BD PF16644.5 KFP00761.1 - 3e-10 40.4 0.1 5e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin Claudin_2 PF13903.6 KFP00762.1 - 6.7e-29 101.0 4.1 9.5e-29 100.5 4.1 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFP00762.1 - 0.006 16.5 7.6 0.11 12.4 4.8 2.6 2 1 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family Pkinase PF00069.25 KFP00763.1 - 1.5e-145 483.5 0.0 8.5e-73 244.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFP00763.1 - 1.4e-75 254.0 0.0 6.9e-40 137.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFP00763.1 - 8.2e-13 48.3 0.0 3.5e-07 29.8 0.0 3.1 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 KFP00763.1 - 5.5e-11 42.2 0.0 4.1e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFP00763.1 - 3e-08 32.9 0.0 0.00097 18.0 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Haspin_kinase PF12330.8 KFP00763.1 - 3.7e-07 29.4 0.4 0.0027 16.7 0.0 2.2 2 0 0 2 2 2 2 Haspin like kinase domain Pkinase_C PF00433.24 KFP00763.1 - 3.4e-06 27.7 1.5 9.7e-06 26.2 1.5 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 KFP00763.1 - 1.3e-05 25.2 0.1 0.24 11.3 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KFP00763.1 - 0.00023 20.7 0.0 0.089 12.3 0.0 2.5 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL FTA2 PF13095.6 KFP00763.1 - 0.00055 19.6 0.1 2.1 7.9 0.0 3.2 3 0 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KFP00763.1 - 0.014 15.0 0.0 0.58 9.7 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.11 KFP00763.1 - 0.13 11.2 0.1 1.9 7.4 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.20 KFP00763.1 - 0.18 11.3 0.1 6.5 6.3 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase Homeodomain PF00046.29 KFP00764.1 - 1.6e-11 43.9 2.2 5e-05 23.1 0.0 2.8 2 0 0 2 2 2 2 Homeodomain DUF1170 PF06663.13 KFP00765.1 - 2.7e-57 193.9 3.2 1.5e-56 191.5 3.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1170) CRIC_ras_sig PF10534.9 KFP00765.1 - 7.5e-38 128.6 1.1 1.9e-37 127.3 0.2 2.2 2 0 0 2 2 2 1 Connector enhancer of kinase suppressor of ras SAM_1 PF00536.30 KFP00765.1 - 7.6e-15 55.1 0.4 2.3e-14 53.6 0.4 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 KFP00765.1 - 4.5e-14 52.8 3.1 1.1e-13 51.6 3.1 1.7 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.17 KFP00765.1 - 3e-10 40.0 0.5 9.5e-10 38.4 0.5 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ PF00595.24 KFP00765.1 - 1.6e-09 37.9 0.0 1.3e-08 35.1 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFP00765.1 - 2.2e-08 33.8 0.1 4.8e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP00765.1 - 0.0041 17.4 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PH_11 PF15413.6 KFP00765.1 - 0.1 13.0 9.8 0.45 11.0 9.8 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain ApoO PF09769.9 KFP00766.1 - 2.7e-38 130.9 0.0 2.7e-38 130.9 0.0 1.4 2 0 0 2 2 2 1 Apolipoprotein O EVI2A PF05399.11 KFP00766.1 - 0.094 12.3 1.1 0.13 11.8 1.1 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Zfx_Zfy_act PF04704.13 KFP00767.1 - 5.8e-153 508.8 16.0 5.8e-153 508.8 16.0 1.8 2 0 0 2 2 2 1 Zfx / Zfy transcription activation region zf-C2H2 PF00096.26 KFP00767.1 - 1.6e-40 135.3 115.6 2.6e-06 27.6 2.9 12.3 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP00767.1 - 4e-35 118.7 118.6 1.1e-05 25.6 2.6 13.1 13 0 0 13 13 13 11 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP00767.1 - 1.1e-31 106.7 110.0 0.0001 22.8 2.3 12.4 12 0 0 12 12 12 12 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFP00767.1 - 7.3e-26 89.6 104.1 3.6e-07 29.8 0.9 12.4 12 0 0 12 12 12 8 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFP00767.1 - 3.1e-10 40.1 82.0 0.016 15.5 0.1 11.8 12 0 0 12 12 12 6 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 KFP00767.1 - 2e-07 31.6 47.9 0.012 16.3 2.7 7.1 4 2 3 7 7 7 4 zinc-ribbon family zf-C2H2_6 PF13912.6 KFP00767.1 - 0.0081 16.1 11.4 0.012 15.7 3.9 8.4 8 0 0 8 8 7 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFP00767.1 - 0.044 13.6 0.5 0.044 13.6 0.5 10.1 11 0 0 11 11 11 0 zinc-finger C2H2-type zf-met PF12874.7 KFP00767.1 - 0.068 13.6 0.1 0.068 13.6 0.1 10.9 11 0 0 11 11 11 0 Zinc-finger of C2H2 type Ribosomal_S17e PF00833.18 KFP00767.1 - 0.085 12.8 0.6 0.22 11.5 0.6 1.6 1 0 0 1 1 1 0 Ribosomal S17 APG6_N PF17675.1 KFP00768.1 - 0.029 14.9 11.1 0.029 14.9 11.1 3.4 1 1 2 3 3 3 0 Apg6 coiled-coil region ATG16 PF08614.11 KFP00768.1 - 0.1 12.8 30.2 0.066 13.4 10.5 2.9 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) CK_II_beta PF01214.18 KFP00768.1 - 0.11 12.3 7.5 0.29 10.9 1.2 2.9 3 0 0 3 3 3 0 Casein kinase II regulatory subunit GIT_CC PF16559.5 KFP00768.1 - 0.23 11.4 0.1 0.23 11.4 0.1 4.3 3 2 3 6 6 6 0 GIT coiled-coil Rho guanine nucleotide exchange factor PKcGMP_CC PF16808.5 KFP00768.1 - 0.65 9.9 20.7 0.59 10.0 0.4 5.0 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF724 PF05266.14 KFP00768.1 - 0.71 9.7 20.5 0.37 10.6 8.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF724) TSC22 PF01166.18 KFP00768.1 - 1 9.7 11.7 1.5 9.2 0.3 3.8 3 1 0 3 3 3 0 TSC-22/dip/bun family ADIP PF11559.8 KFP00768.1 - 3 7.9 26.0 0.86 9.7 7.6 2.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF3323 PF11796.8 KFP00768.1 - 3.3 7.6 6.8 1 9.2 2.8 1.9 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) BRE1 PF08647.11 KFP00768.1 - 4 7.6 18.5 0.033 14.3 3.3 3.7 1 1 3 4 4 4 0 BRE1 E3 ubiquitin ligase Gon7 PF08738.10 KFP00768.1 - 5.5 7.1 8.5 8.3 6.5 1.2 3.1 3 0 0 3 3 3 0 Gon7 family COQ7 PF03232.13 KFP00768.1 - 5.9 6.6 6.8 5.4 6.8 0.1 3.2 2 1 0 3 3 3 0 Ubiquinone biosynthesis protein COQ7 Csm1_N PF18504.1 KFP00768.1 - 6.2 7.2 19.2 1.9 8.9 1.9 4.4 3 2 0 4 4 4 0 Csm1 N-terminal domain GAS PF13851.6 KFP00768.1 - 9.5 5.5 25.4 70 2.7 7.6 3.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding GDI PF00996.18 KFP00769.1 - 2.5e-57 194.4 0.0 7.3e-45 153.3 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor FAD_binding_2 PF00890.24 KFP00769.1 - 0.0002 20.6 0.0 0.0003 20.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KFP00769.1 - 0.00033 20.1 0.0 0.00061 19.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFP00769.1 - 0.0023 18.1 0.1 0.0064 16.7 0.0 1.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Podoplanin PF05808.11 KFP00769.1 - 0.061 13.4 1.2 0.15 12.2 1.2 1.6 1 0 0 1 1 1 0 Podoplanin Band_7 PF01145.25 KFP00770.1 - 0.082 12.9 0.5 0.15 12.1 0.5 1.5 1 0 0 1 1 1 0 SPFH domain / Band 7 family DDE_Tnp_1_6 PF13751.6 KFP00770.1 - 0.19 11.9 5.1 0.38 11.0 5.1 1.4 1 0 0 1 1 1 0 Transposase DDE domain DUF4778 PF16008.5 KFP00770.1 - 1.7 8.6 9.6 3.7 7.5 9.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Kelch_1 PF01344.25 KFP00771.1 - 6.7e-76 249.7 23.6 5.7e-15 54.6 0.2 6.6 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 KFP00771.1 - 1.8e-50 167.7 6.5 1e-09 38.3 0.0 6.3 2 2 4 6 6 6 6 Kelch motif BACK PF07707.15 KFP00771.1 - 1e-31 109.1 2.3 1.4e-31 108.6 0.0 2.4 3 0 0 3 3 3 1 BTB And C-terminal Kelch BTB PF00651.31 KFP00771.1 - 8.9e-31 106.4 2.3 1.2e-30 105.9 1.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 KFP00771.1 - 4.8e-25 86.5 7.7 4e-06 26.6 0.0 7.2 7 0 0 7 7 7 5 Kelch motif Kelch_4 PF13418.6 KFP00771.1 - 4.4e-24 84.2 10.7 0.0003 20.7 0.1 6.3 3 1 3 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP00771.1 - 1.9e-17 63.1 11.6 0.024 14.9 0.2 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP00771.1 - 3.9e-05 23.5 6.6 0.51 10.4 0.0 5.9 6 0 0 6 6 6 1 Kelch motif Hydrolase PF00702.26 KFP00771.1 - 0.083 13.2 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF3342 PF11822.8 KFP00771.1 - 0.14 12.3 0.7 8.4 6.7 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3342) PQQ_3 PF13570.6 KFP00771.1 - 2 9.0 7.4 66 4.2 0.1 4.5 4 0 0 4 4 4 0 PQQ-like domain Cadherin PF00028.17 KFP00772.1 - 2.6e-113 370.7 5.2 2.1e-22 79.4 0.1 7.5 7 0 0 7 7 7 7 Cadherin domain Protocadherin PF08374.11 KFP00772.1 - 1.5e-85 286.6 3.4 2.4e-85 286.0 3.4 1.3 1 0 0 1 1 1 1 Protocadherin Cadherin_2 PF08266.12 KFP00772.1 - 5.3e-20 71.0 0.1 8.3e-09 35.2 0.1 5.2 5 0 0 5 5 5 3 Cadherin-like Cadherin_3 PF16184.5 KFP00772.1 - 3e-08 33.7 10.5 0.008 16.2 0.1 5.8 5 0 0 5 5 5 3 Cadherin-like Cadherin_4 PF17803.1 KFP00772.1 - 0.0084 16.7 36.9 0.039 14.6 0.6 6.0 7 0 0 7 7 7 3 Bacterial cadherin-like domain TMEM154 PF15102.6 KFP00772.1 - 0.013 15.4 0.3 0.035 14.0 0.3 1.7 1 0 0 1 1 1 0 TMEM154 protein family RET_CLD1 PF17756.1 KFP00772.1 - 0.018 15.4 0.0 2.4 8.5 0.0 2.9 2 0 0 2 2 2 0 RET Cadherin like domain 1 Big_9 PF17963.1 KFP00772.1 - 0.022 15.5 27.5 3.3 8.5 1.1 5.6 5 0 0 5 5 5 0 Bacterial Ig domain AP3D1 PF06375.11 KFP00772.1 - 0.027 14.7 0.9 0.062 13.5 0.9 1.5 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Y_Y_Y PF07495.13 KFP00772.1 - 0.075 13.0 0.0 1.4 8.9 0.0 3.2 3 0 0 3 3 3 0 Y_Y_Y domain Cadherin_C_2 PF16492.5 KFP00772.1 - 0.12 13.2 0.0 1.2 9.9 0.0 2.5 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal EphA2_TM PF14575.6 KFP00772.1 - 0.13 13.2 0.2 0.52 11.2 0.2 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain He_PIG PF05345.12 KFP00772.1 - 0.52 10.5 7.9 4 7.7 0.0 4.8 5 1 0 5 5 4 0 Putative Ig domain BRICHOS PF04089.14 KFP00775.1 - 1.3e-16 60.6 0.0 2.6e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 BRICHOS domain Tetraspanin PF00335.20 KFP00776.1 - 9.1e-30 104.1 5.8 1e-29 103.9 5.8 1.0 1 0 0 1 1 1 1 Tetraspanin family FixQ PF05545.11 KFP00776.1 - 0.0025 17.8 0.3 0.0046 16.9 0.3 1.5 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ OppC_N PF12911.7 KFP00776.1 - 0.55 10.2 2.1 11 6.1 0.5 2.4 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF4190 PF13828.6 KFP00776.1 - 0.56 10.0 0.0 0.56 10.0 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) YccF PF03733.13 KFP00776.1 - 1 10.1 6.0 0.74 10.6 1.1 2.2 2 0 0 2 2 2 0 Inner membrane component domain FeoB_C PF07664.12 KFP00776.1 - 1.1 9.0 4.2 0.41 10.4 0.3 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus DUF4174 PF13778.6 KFP00777.1 - 1.1e-31 109.8 0.0 1.6e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) Sushi PF00084.20 KFP00777.1 - 1.7e-26 92.6 22.9 6.6e-11 42.6 5.7 3.6 3 0 0 3 3 3 3 Sushi repeat (SCR repeat) HYR PF02494.16 KFP00777.1 - 2.8e-26 91.6 0.0 4.7e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 HYR domain Antistasin PF02822.14 KFP00777.1 - 5.4 7.7 16.1 15 6.4 0.1 4.6 3 1 1 4 4 4 0 Antistasin family Met_10 PF02475.16 KFP00778.1 - 3e-29 102.2 0.0 3.7e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 KFP00778.1 - 0.00098 18.7 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Trm5_N PF18093.1 KFP00778.1 - 0.025 14.5 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 tRNA methyltransferase 5 N-terminal domain Cons_hypoth95 PF03602.15 KFP00778.1 - 0.093 12.4 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Sirohm_synth_M PF14824.6 KFP00778.1 - 0.59 9.6 2.0 1.6 8.2 0.4 2.3 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central PhoLip_ATPase_C PF16212.5 KFP00779.1 - 1.4e-73 247.7 33.0 1.4e-73 247.7 33.0 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFP00779.1 - 4.5e-23 80.7 0.3 4.5e-23 80.7 0.3 2.7 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 KFP00779.1 - 4.8e-11 42.5 0.0 4.8e-11 42.5 0.0 2.9 2 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KFP00779.1 - 1.7e-10 40.9 0.0 7.9e-10 38.7 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFP00779.1 - 4e-08 33.8 3.6 8e-05 23.0 2.8 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF63 PF01889.17 KFP00779.1 - 0.0033 17.7 6.2 0.0089 16.2 6.2 1.7 1 0 0 1 1 1 1 Membrane protein of unknown function DUF63 Hydrolase_3 PF08282.12 KFP00779.1 - 0.0062 16.3 0.1 0.5 10.1 0.0 3.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase VPS13_mid_rpt PF16910.5 KFP00779.1 - 0.081 12.3 0.3 0.16 11.4 0.3 1.4 1 0 0 1 1 1 0 Repeating coiled region of VPS13 RhoGEF PF00621.20 KFP00780.1 - 6.4e-20 72.2 0.1 6.4e-20 72.2 0.1 3.4 3 1 0 3 3 3 1 RhoGEF domain CRAL_TRIO_2 PF13716.6 KFP00780.1 - 1.5e-07 31.7 0.0 4.5e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PH PF00169.29 KFP00780.1 - 1.2e-06 29.0 0.2 3e-06 27.7 0.2 1.7 1 0 0 1 1 1 1 PH domain Spectrin PF00435.21 KFP00780.1 - 0.0068 16.9 1.4 0.0068 16.9 1.4 4.1 5 2 0 5 5 5 1 Spectrin repeat YojJ PF10372.9 KFP00780.1 - 0.019 15.0 2.2 0.64 10.2 0.1 3.3 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus PH_10 PF15411.6 KFP00780.1 - 0.081 13.2 0.8 0.18 12.1 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain Crp PF00325.20 KFP00780.1 - 0.15 11.7 0.1 0.68 9.6 0.1 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family Lzipper-MIP1 PF14389.6 KFP00780.1 - 0.15 12.3 2.2 0.54 10.6 1.6 2.4 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Trypsin PF00089.26 KFP00781.1 - 4.3e-64 216.4 0.7 5.7e-64 215.9 0.7 1.2 1 0 0 1 1 1 1 Trypsin Gla PF00594.20 KFP00781.1 - 2.3e-21 75.7 10.3 4e-21 74.9 10.3 1.4 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain FXa_inhibition PF14670.6 KFP00781.1 - 7.8e-14 51.7 22.6 7.6e-12 45.3 7.4 2.8 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site EGF PF00008.27 KFP00781.1 - 1.1e-08 35.2 18.7 2.6e-07 30.8 5.8 2.9 2 0 0 2 2 2 2 EGF-like domain cEGF PF12662.7 KFP00781.1 - 8.6e-08 32.0 7.8 0.00029 20.7 1.0 2.9 2 0 0 2 2 2 2 Complement Clr-like EGF-like DUF1986 PF09342.11 KFP00781.1 - 1e-05 25.9 0.0 1.9e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 KFP00781.1 - 8.5e-05 23.5 0.2 0.00018 22.4 0.2 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain hEGF PF12661.7 KFP00781.1 - 0.00019 21.9 3.4 0.00019 21.9 3.4 4.1 4 0 0 4 4 3 1 Human growth factor-like EGF EGF_3 PF12947.7 KFP00781.1 - 0.071 13.3 22.2 0.51 10.6 6.6 2.8 2 0 0 2 2 2 0 EGF domain Haemagg_act PF05860.13 KFP00781.1 - 0.072 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 haemagglutination activity domain EGF_CA PF07645.15 KFP00781.1 - 0.11 12.7 19.3 0.61 10.3 12.2 3.1 2 1 0 2 2 2 0 Calcium-binding EGF domain FGF PF00167.18 KFP00782.1 - 6.4e-44 149.0 0.4 8.2e-44 148.7 0.4 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.13 KFP00782.1 - 0.00018 21.7 0.1 0.0017 18.6 0.0 2.0 1 1 1 2 2 2 1 Fascin domain TGF_beta_GS PF08515.12 KFP00782.1 - 0.096 12.2 0.5 0.2 11.2 0.5 1.5 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif zf_ZIC PF18366.1 KFP00784.1 - 4.1e-27 94.0 0.5 4.1e-27 94.0 0.5 3.8 4 0 0 4 4 4 1 Zic proteins zinc finger domain zf-C2H2 PF00096.26 KFP00784.1 - 2.3e-22 78.1 31.6 2.6e-06 27.5 3.0 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP00784.1 - 1.1e-14 54.0 43.9 7.6e-07 29.3 0.3 5.9 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFP00784.1 - 7.4e-08 32.5 13.6 0.005 17.1 0.2 5.0 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KFP00784.1 - 5.6e-07 29.9 48.7 0.0012 19.6 1.9 6.2 6 0 0 6 6 6 5 C2H2-type zinc finger zf-met PF12874.7 KFP00784.1 - 0.00015 22.0 12.9 0.0002 21.6 1.0 4.3 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFP00784.1 - 0.00067 19.6 14.0 0.00094 19.1 1.8 4.2 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFP00784.1 - 0.002 18.4 12.6 0.033 14.5 1.7 3.2 1 1 2 3 3 3 3 C2H2-type zinc ribbon Zf_RING PF16744.5 KFP00784.1 - 0.06 13.5 0.4 0.23 11.6 0.1 2.1 2 1 0 2 2 2 0 KIAA1045 RING finger CH_2 PF06294.11 KFP00784.1 - 0.19 11.9 0.0 0.47 10.6 0.0 1.7 1 0 0 1 1 1 0 CH-like domain in sperm protein EMP70 PF02990.16 KFP00785.1 - 2.6e-216 719.3 11.6 3.3e-216 719.0 11.6 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 RRM_1 PF00076.22 KFP00786.1 - 3.9e-23 81.0 0.1 5.8e-23 80.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM1CTR PF08081.11 KFP00786.1 - 3.4e-21 75.0 18.8 3.4e-21 75.0 18.8 9.8 6 1 1 7 7 7 1 RBM1CTR (NUC064) family RRM_7 PF16367.5 KFP00786.1 - 0.01 15.9 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif RRM_5 PF13893.6 KFP00786.1 - 0.04 13.5 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP00786.1 - 0.062 13.2 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif PHM7_cyt PF14703.6 KFP00786.1 - 0.19 11.9 0.0 0.3 11.3 0.0 1.2 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter RhoGEF67_u2 PF16614.5 KFP00787.1 - 1.6e-53 179.3 1.3 1.6e-53 179.3 1.3 2.5 2 0 0 2 2 2 1 Unstructured region two on RhoGEF 6 and 7 betaPIX_CC PF16523.5 KFP00787.1 - 1.3e-37 127.5 8.1 1.3e-37 127.5 8.1 3.3 4 0 0 4 4 4 1 betaPIX coiled coil RhoGEF PF00621.20 KFP00787.1 - 3e-32 112.3 1.1 3e-32 112.3 1.1 2.3 2 0 0 2 2 2 1 RhoGEF domain SH3_9 PF14604.6 KFP00787.1 - 2e-17 62.8 0.1 4.2e-17 61.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain CH PF00307.31 KFP00787.1 - 2.5e-17 63.0 0.0 6.6e-17 61.7 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain SH3_2 PF07653.17 KFP00787.1 - 2.6e-16 59.0 0.4 5.2e-16 58.1 0.4 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP00787.1 - 1.6e-14 53.2 0.3 3e-14 52.3 0.3 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 KFP00787.1 - 3.5e-10 40.3 0.0 1.1e-09 38.8 0.0 1.8 2 0 0 2 2 1 1 PH domain RhoGEF67_u1 PF16615.5 KFP00787.1 - 2.4e-09 37.5 3.9 2.4e-09 37.5 3.9 2.9 2 0 0 2 2 2 1 Unstructured region one on RhoGEF 6 and 7 CAMSAP_CH PF11971.8 KFP00787.1 - 0.00074 19.3 0.0 0.0023 17.7 0.0 1.8 1 0 0 1 1 1 1 CAMSAP CH domain Nmad5 PF18757.1 KFP00787.1 - 0.024 14.9 2.0 0.25 11.5 0.9 2.5 2 0 0 2 2 2 0 Nucleotide modification associated domain 5 SHE3 PF17078.5 KFP00787.1 - 0.29 10.8 12.7 0.43 10.3 0.7 3.4 3 0 0 3 3 3 0 SWI5-dependent HO expression protein 3 DUF4559 PF15112.6 KFP00787.1 - 0.47 10.1 6.5 0.64 9.6 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4559) CENP-Q PF13094.6 KFP00787.1 - 0.75 10.0 17.2 0.06 13.5 6.7 3.3 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit ZapB PF06005.12 KFP00787.1 - 1.9 9.0 17.6 0.12 12.8 5.9 3.6 3 0 0 3 3 3 0 Cell division protein ZapB SKA1 PF07160.12 KFP00787.1 - 2.5 7.9 10.9 0.2 11.5 3.0 2.9 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 She9_MDM33 PF05546.11 KFP00787.1 - 3 7.6 8.0 6.7 6.5 0.3 2.4 2 0 0 2 2 2 0 She9 / Mdm33 family RPW8 PF05659.11 KFP00787.1 - 3.6 7.3 11.5 2.7 7.7 0.5 2.9 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Nsp1_C PF05064.13 KFP00787.1 - 4 7.3 11.1 0.27 11.1 1.7 3.5 4 1 1 5 5 5 0 Nsp1-like C-terminal region OmpH PF03938.14 KFP00787.1 - 4.8 7.5 11.2 3.7 7.9 0.3 3.3 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) DUF724 PF05266.14 KFP00787.1 - 5.9 6.7 10.1 2.8 7.7 4.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TNF PF00229.18 KFP00788.1 - 1.5e-31 109.0 0.6 3.1e-31 108.0 0.2 1.7 2 0 0 2 2 2 1 TNF(Tumour Necrosis Factor) family C1q PF00386.21 KFP00788.1 - 0.00062 20.0 0.2 0.0022 18.2 0.2 1.9 1 1 0 1 1 1 1 C1q domain Casein PF00363.18 KFP00788.1 - 0.2 12.1 0.9 8 6.9 0.2 2.3 1 1 1 2 2 2 0 Casein Vg_Tdu PF07545.14 KFP00790.1 - 9.2e-20 70.1 0.3 1.7e-19 69.2 0.3 1.5 1 0 0 1 1 1 1 Vestigial/Tondu family RRM_1 PF00076.22 KFP00791.1 - 3e-17 62.2 0.1 6e-07 29.2 0.0 3.8 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP00791.1 - 0.011 15.8 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif RRM_occluded PF16842.5 KFP00791.1 - 0.035 14.0 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF1998 PF09369.10 KFP00791.1 - 0.11 13.3 0.1 1.5 9.7 0.0 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF1998) 7tm_1 PF00001.21 KFP00792.1 - 1.1e-57 195.4 14.4 1.6e-57 194.9 14.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP00792.1 - 4e-11 42.8 13.8 6.6e-11 42.1 13.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 KFP00792.1 - 3.1e-09 36.6 14.4 4.1e-09 36.2 14.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 KFP00792.1 - 1.9e-06 27.7 9.8 1.9e-06 27.7 9.8 1.8 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF3810 PF12725.7 KFP00792.1 - 0.12 11.7 2.7 0.31 10.4 2.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) TAS2R PF05296.13 KFP00792.1 - 0.85 8.7 17.7 3.6 6.6 17.7 2.0 1 1 0 1 1 1 0 Taste receptor protein (TAS2R) Gaa1 PF04114.14 KFP00792.1 - 1 8.3 9.7 0.3 10.1 1.9 2.0 2 0 0 2 2 2 0 Gaa1-like, GPI transamidase component MAP7 PF05672.11 KFP00793.1 - 1.1e-45 155.2 78.2 1.1e-45 155.2 78.2 3.3 2 1 1 3 3 3 2 MAP7 (E-MAP-115) family LIM PF00412.22 KFP00794.1 - 1.4e-47 159.7 72.1 7.5e-13 48.5 10.1 5.1 5 0 0 5 5 5 5 LIM domain zf-RING_6 PF14835.6 KFP00794.1 - 0.0052 16.6 2.1 0.0052 16.6 2.1 5.3 5 1 0 5 5 5 2 zf-RING of BARD1-type protein Ureidogly_lyase PF04115.12 KFP00794.1 - 0.025 14.4 0.1 2.2 8.0 0.0 2.9 1 1 1 2 2 2 0 Ureidoglycolate lyase Sgf11 PF08209.11 KFP00794.1 - 0.036 13.6 0.4 0.036 13.6 0.4 9.3 10 3 3 13 13 13 0 Sgf11 (transcriptional regulation protein) FRD2 PF03197.13 KFP00794.1 - 0.53 10.6 10.4 0.51 10.7 0.6 3.4 3 1 0 4 4 4 0 Bacteriophage FRD2 protein Na_H_Exchanger PF00999.21 KFP00795.1 - 1.3e-78 264.5 38.7 3.6e-78 263.0 38.7 1.6 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Reo_sigmaC PF04582.12 KFP00795.1 - 0.051 13.8 0.5 0.13 12.5 0.1 1.9 2 0 0 2 2 2 0 Reovirus sigma C capsid protein C-terminal domain Stevor PF17410.2 KFP00795.1 - 0.18 11.3 0.1 0.56 9.7 0.0 1.8 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame DUF3981 PF13139.6 KFP00795.1 - 4.4 7.7 6.1 5.9 7.3 0.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3981) MMgT PF10270.9 KFP00796.1 - 1.1e-06 28.9 0.0 1.6e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Membrane magnesium transporter Motile_Sperm PF00635.26 KFP00797.1 - 3.2e-17 62.3 0.4 4.8e-17 61.8 0.1 1.4 1 1 0 1 1 1 1 MSP (Major sperm protein) domain Pribosyltran PF00156.27 KFP00800.1 - 9.2e-15 54.5 0.0 1.8e-14 53.6 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain zf-HC5HC2H PF13771.6 KFP00801.1 - 1.5e-34 118.1 31.6 6.4e-18 64.8 9.4 3.6 4 0 0 4 4 4 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFP00801.1 - 7.9e-14 51.8 29.3 3.7e-07 30.3 13.1 2.9 2 2 1 3 3 3 2 PHD-zinc-finger like domain zf-ANAPC11 PF12861.7 KFP00801.1 - 0.32 11.1 14.4 3.7 7.7 0.5 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2H2 PF00096.26 KFP00802.1 - 2e-12 46.8 8.8 5.8e-07 29.6 2.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP00802.1 - 1.2e-09 38.2 8.1 1.6e-05 25.3 1.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP00802.1 - 2.3e-09 37.2 12.9 3e-07 30.6 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf_UBZ PF18439.1 KFP00802.1 - 0.00015 21.3 1.6 0.046 13.3 0.2 2.3 2 1 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 KFP00802.1 - 0.00022 20.9 5.0 0.021 14.6 0.3 2.1 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFP00802.1 - 0.00088 19.5 5.0 0.0084 16.4 0.4 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding XPA_N PF01286.18 KFP00802.1 - 0.0024 17.9 4.1 0.014 15.4 0.3 2.2 2 0 0 2 2 2 1 XPA protein N-terminal zf-C2H2_6 PF13912.6 KFP00802.1 - 0.0038 17.2 10.1 0.029 14.4 4.7 2.4 2 2 0 2 2 2 1 C2H2-type zinc finger LIM PF00412.22 KFP00802.1 - 0.012 15.8 0.6 0.018 15.3 0.6 1.3 1 1 0 1 1 1 0 LIM domain zf-met PF12874.7 KFP00802.1 - 0.018 15.4 5.7 0.9 10.0 0.2 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn_Tnp_IS1595 PF12760.7 KFP00802.1 - 0.019 15.0 5.0 0.16 12.0 5.0 2.0 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 KFP00802.1 - 0.023 14.8 3.7 0.17 12.0 3.8 2.0 1 1 1 2 2 2 0 Zinc ribbon domain Metallothio_Pro PF02069.16 KFP00802.1 - 0.03 14.6 0.8 0.043 14.1 0.8 1.3 1 1 0 1 1 1 0 Prokaryotic metallothionein zf-ribbon_3 PF13248.6 KFP00802.1 - 0.033 13.6 5.6 0.52 9.8 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-Mss51 PF13824.6 KFP00802.1 - 0.052 13.6 0.5 0.052 13.6 0.5 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 IBR PF01485.21 KFP00802.1 - 0.054 13.7 3.0 0.78 10.0 0.1 2.0 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain PHD PF00628.29 KFP00802.1 - 0.062 13.2 2.2 0.076 12.9 2.2 1.1 1 0 0 1 1 1 0 PHD-finger CpXC PF14353.6 KFP00802.1 - 0.072 13.1 0.6 5.6 7.0 0.1 2.0 1 1 1 2 2 2 0 CpXC protein zinc_ribbon_4 PF13717.6 KFP00802.1 - 0.086 12.8 2.5 0.56 10.2 2.5 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zf-Di19 PF05605.12 KFP00802.1 - 0.13 12.6 2.2 2 8.7 0.2 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding YhfH PF14149.6 KFP00802.1 - 0.15 12.1 3.8 2.4 8.2 0.1 2.2 2 0 0 2 2 2 0 YhfH-like protein HNH PF01844.23 KFP00802.1 - 0.18 12.0 5.0 1.6 9.0 0.3 2.7 2 1 0 2 2 2 0 HNH endonuclease ADK_lid PF05191.14 KFP00802.1 - 0.22 11.5 2.9 0.25 11.4 2.0 1.7 1 1 0 1 1 1 0 Adenylate kinase, active site lid zinc_ribbon_9 PF14369.6 KFP00802.1 - 0.23 11.8 8.2 1.7 9.0 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon zf-LYAR PF08790.11 KFP00802.1 - 0.26 11.2 5.6 4.4 7.3 0.6 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-AN1 PF01428.16 KFP00802.1 - 0.64 10.2 6.3 17 5.7 6.3 2.4 1 1 0 1 1 1 0 AN1-like Zinc finger zf-H2C2_5 PF13909.6 KFP00802.1 - 0.93 9.3 8.1 6.5 6.6 0.5 2.9 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-RING_7 PF02591.15 KFP00802.1 - 1.1 9.4 0.2 1.1 9.4 0.2 2.4 3 0 0 3 3 2 0 C4-type zinc ribbon domain zinc_ribbon_2 PF13240.6 KFP00802.1 - 1.4 8.8 8.1 3.2 7.6 0.5 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_11 PF16622.5 KFP00803.1 - 3.1e-12 46.0 6.7 9.4e-06 25.3 0.6 2.1 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2 PF00096.26 KFP00803.1 - 4.5e-10 39.4 7.9 5.5e-05 23.4 0.9 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP00803.1 - 1.4e-06 28.6 7.7 0.005 17.6 0.9 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger XPA_N PF01286.18 KFP00803.1 - 7.3e-06 25.9 4.1 0.028 14.5 0.5 2.1 2 0 0 2 2 2 2 XPA protein N-terminal zf-LYAR PF08790.11 KFP00803.1 - 2.4e-05 24.1 1.7 0.1 12.5 0.1 2.2 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger HNH PF01844.23 KFP00803.1 - 3.4e-05 23.9 2.7 0.12 12.5 0.2 2.1 2 0 0 2 2 2 2 HNH endonuclease Zn-ribbon_8 PF09723.10 KFP00803.1 - 9.2e-05 22.5 3.2 0.0013 18.8 3.7 2.0 1 1 1 2 2 2 2 Zinc ribbon domain zf-C2H2_6 PF13912.6 KFP00803.1 - 0.00018 21.4 2.6 0.24 11.5 0.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.15 KFP00803.1 - 0.00062 19.7 5.8 0.2 11.7 1.5 2.1 1 1 1 2 2 2 2 BED zinc finger zf-C2H2_jaz PF12171.8 KFP00803.1 - 0.00065 19.9 0.3 1.1 9.7 0.0 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KFP00803.1 - 0.00066 20.0 11.6 0.018 15.5 0.8 3.2 3 0 0 3 3 3 2 Zinc-finger double domain Zn_ribbon_SprT PF17283.2 KFP00803.1 - 0.0023 17.8 4.4 0.15 12.0 0.4 2.1 2 0 0 2 2 2 2 SprT-like zinc ribbon domain zf_UBZ PF18439.1 KFP00803.1 - 0.0036 16.8 2.6 0.58 9.8 0.2 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf_C2H2_ZHX PF18387.1 KFP00803.1 - 0.0082 15.8 4.5 0.35 10.6 0.4 2.1 1 1 1 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain YhfH PF14149.6 KFP00803.1 - 0.0087 16.0 2.2 2.4 8.2 0.1 2.2 2 0 0 2 2 2 2 YhfH-like protein DUF2199 PF09965.9 KFP00803.1 - 0.012 15.7 1.5 2.7 8.0 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2199) DUF2256 PF10013.9 KFP00803.1 - 0.013 15.6 0.6 3.3 7.9 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) TFIIS_C PF01096.18 KFP00803.1 - 0.013 15.3 3.2 1.5 8.8 0.3 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) FYVE PF01363.21 KFP00803.1 - 0.015 15.5 5.4 0.3 11.3 0.5 2.0 1 1 1 2 2 2 0 FYVE zinc finger Ephrin_rec_like PF07699.13 KFP00803.1 - 0.019 14.7 1.3 1.4 8.8 0.1 2.1 2 0 0 2 2 2 0 Putative ephrin-receptor like zf-trcl PF13451.6 KFP00803.1 - 0.039 13.9 2.3 4 7.4 0.2 2.1 2 0 0 2 2 2 0 Probable zinc-ribbon domain DNA_RNApol_7kD PF03604.13 KFP00803.1 - 0.058 13.1 1.6 2.4 7.9 0.1 2.4 2 2 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_3rep PF18868.1 KFP00803.1 - 0.07 13.8 1.1 10 6.8 0.1 2.0 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-Dof PF02701.15 KFP00803.1 - 0.087 13.0 0.3 1.7 8.8 0.1 2.0 1 1 1 2 2 2 0 Dof domain, zinc finger zf-C2H2_2 PF12756.7 KFP00803.1 - 0.091 13.1 3.4 3.9 7.9 0.3 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) ROS_MUCR PF05443.11 KFP00803.1 - 0.17 12.0 0.9 13 5.8 0.1 2.0 1 1 1 2 2 2 0 ROS/MUCR transcriptional regulator protein BDHCT PF08072.11 KFP00803.1 - 0.18 11.9 0.5 15 5.8 0.1 2.1 2 0 0 2 2 2 0 BDHCT (NUC031) domain ProRS-C_1 PF09180.11 KFP00803.1 - 0.19 12.0 1.0 3.4 7.9 0.1 2.0 1 1 1 2 2 2 0 Prolyl-tRNA synthetase, C-terminal HypA PF01155.19 KFP00803.1 - 0.19 11.8 1.6 0.42 10.7 1.6 1.5 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-dskA_traR PF01258.17 KFP00803.1 - 0.46 10.5 4.0 6 6.9 0.5 2.2 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger ADD_DNMT3 PF17980.1 KFP00803.1 - 1.4 8.9 6.6 0.83 9.7 2.8 2.2 1 1 1 2 2 2 0 Cysteine rich ADD domain in DNMT3 zf-C2HC5 PF06221.13 KFP00803.1 - 2.8 8.0 8.2 1.2 9.1 0.3 2.6 1 1 2 3 3 3 0 Putative zinc finger motif, C2HC5-type TMF_DNA_bd PF12329.8 KFP00805.1 - 0.014 15.4 1.0 0.029 14.4 1.0 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding C1q PF00386.21 KFP00808.1 - 3.7e-25 88.6 0.3 4e-24 85.2 0.0 3.0 2 0 0 2 2 2 1 C1q domain EMI PF07546.13 KFP00808.1 - 1.5e-14 54.5 2.9 5.9e-14 52.6 2.9 2.1 1 0 0 1 1 1 1 EMI domain EGF PF00008.27 KFP00808.1 - 1.3e-05 25.4 7.1 1.3e-05 25.4 7.1 1.7 2 0 0 2 2 1 1 EGF-like domain hEGF PF12661.7 KFP00808.1 - 0.0086 16.7 5.9 0.022 15.4 5.9 1.7 1 0 0 1 1 1 1 Human growth factor-like EGF Protoglobin PF11563.8 KFP00808.1 - 0.025 14.5 0.2 0.061 13.2 0.2 1.6 1 0 0 1 1 1 0 Protoglobin BclA_C PF18573.1 KFP00808.1 - 0.045 13.7 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 BclA C-terminal domain Baculo_PEP_C PF04513.12 KFP00808.1 - 0.045 13.8 0.5 0.045 13.8 0.5 6.1 5 2 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2497 PF10691.9 KFP00808.1 - 0.35 11.3 0.0 0.35 11.3 0.0 3.6 5 0 0 5 5 3 0 Protein of unknown function (DUF2497) DUF2521 PF10730.9 KFP00808.1 - 0.52 10.3 4.5 0.25 11.4 0.1 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF2521) DUF3372 PF11852.8 KFP00808.1 - 0.67 9.4 3.9 22 4.5 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3372) ER PF01133.17 KFP00808.1 - 0.98 9.5 6.2 2.4 8.2 0.6 3.8 2 2 1 3 3 3 0 Enhancer of rudimentary Mvb12 PF09452.10 KFP00808.1 - 2 8.9 7.1 4 7.9 0.0 4.0 3 1 1 4 4 4 0 ESCRT-I subunit Mvb12 DUF842 PF05811.13 KFP00808.1 - 6.4 6.5 15.9 0.51 10.0 3.5 4.2 3 1 0 3 3 3 0 Eukaryotic protein of unknown function (DUF842) EGF_3 PF12947.7 KFP00808.1 - 8.9 6.6 8.1 21 5.4 8.1 1.7 1 0 0 1 1 1 0 EGF domain Synuclein PF01387.17 KFP00810.1 - 4.5e-55 185.5 18.2 5.2e-55 185.3 18.2 1.0 1 0 0 1 1 1 1 Synuclein RhoGAP PF00620.27 KFP00811.1 - 6.8e-45 152.6 0.5 3.9e-44 150.2 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain PKS_DE PF18369.1 KFP00811.1 - 0.15 12.6 0.4 0.45 11.1 0.4 1.8 1 0 0 1 1 1 0 Polyketide synthase dimerisation element domain HBM PF16591.5 KFP00811.1 - 0.49 9.8 10.1 0.17 11.3 0.4 3.4 3 0 0 3 3 3 0 Helical bimodular sensor domain Dsh_C PF12316.8 KFP00811.1 - 3.3 8.1 9.3 9.8 6.5 9.3 1.7 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal RCC1 PF00415.18 KFP00812.1 - 2.1e-84 277.9 31.2 4.6e-14 52.8 0.1 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.25 KFP00812.1 - 7.8e-82 275.2 0.4 1.1e-81 274.7 0.4 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1_2 PF13540.6 KFP00812.1 - 1.4e-47 158.6 42.1 5.6e-10 38.8 0.1 7.7 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Peptidase_C25_C PF03785.14 KFP00812.1 - 0.06 13.2 0.1 0.73 9.7 0.0 2.8 2 1 1 3 3 3 0 Peptidase family C25, C terminal ig-like domain HECT PF00632.25 KFP00813.1 - 7.3e-26 91.4 0.0 8e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Trm112p PF03966.16 KFP00814.1 - 9.3e-05 22.9 0.5 0.00031 21.3 0.0 2.0 2 1 0 2 2 2 1 Trm112p-like protein RNA_pol_Rpb2_6 PF00562.28 KFP00815.1 - 2.6e-128 428.4 0.2 3.7e-128 427.9 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_2 PF04561.14 KFP00815.1 - 3e-56 190.1 0.0 9e-56 188.5 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_1 PF04563.15 KFP00815.1 - 8.2e-56 188.7 0.0 2e-55 187.5 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KFP00815.1 - 4e-34 116.9 1.5 7.7e-34 116.0 0.2 2.2 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 KFP00815.1 - 3e-24 85.1 0.8 7.7e-24 83.8 0.8 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KFP00815.1 - 6.5e-24 83.9 0.0 1.6e-23 82.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KFP00815.1 - 8.1e-19 67.9 0.5 2e-18 66.7 0.5 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Amidoligase_2 PF12224.8 KFP00815.1 - 0.022 14.4 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme zf-H2C2_2 PF13465.6 KFP00816.1 - 6.6e-27 92.7 69.2 3.4e-08 33.5 1.3 11.3 11 1 0 11 11 11 6 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFP00816.1 - 1.2e-26 92.1 68.9 5.6e-07 29.2 4.5 8.7 9 0 0 9 9 9 6 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFP00816.1 - 1.9e-15 56.4 79.6 0.00053 20.3 4.5 9.5 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP00816.1 - 1.8e-10 40.8 75.4 0.08 13.8 0.8 9.6 9 0 0 9 9 9 8 C2H2-type zinc finger SARAF PF06682.12 KFP00817.1 - 6.9e-77 259.3 1.9 7.7e-77 259.2 1.9 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Cytochrom_B561 PF03188.16 KFP00817.1 - 0.0098 16.0 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Vps55 PF04133.14 KFP00818.1 - 2.6e-29 101.5 2.3 2.9e-29 101.4 2.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 SRP72 PF08492.12 KFP00819.1 - 3.3e-22 78.6 10.5 3.3e-22 78.6 10.5 3.0 2 0 0 2 2 2 1 SRP72 RNA-binding domain SRP_TPR_like PF17004.5 KFP00819.1 - 9.9e-21 73.9 8.8 1.7e-20 73.2 3.2 3.2 2 1 0 3 3 3 1 Putative TPR-like repeat TPR_2 PF07719.17 KFP00819.1 - 8.5e-16 56.7 14.6 0.0063 16.5 0.0 7.9 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFP00819.1 - 3.9e-15 56.1 15.1 0.0047 17.4 0.1 7.4 4 3 3 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFP00819.1 - 4e-13 49.0 6.7 0.38 11.7 0.0 7.8 6 3 2 8 8 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFP00819.1 - 9.6e-11 41.0 8.1 0.026 14.3 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP00819.1 - 8.3e-10 38.8 19.3 4.7e-05 23.5 2.5 6.2 4 3 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KFP00819.1 - 2.3e-08 33.6 12.4 0.084 13.1 0.6 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFP00819.1 - 1.9e-07 31.2 21.2 0.0002 21.6 1.2 7.0 7 3 1 8 8 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFP00819.1 - 5.5e-07 29.8 16.8 0.51 11.1 0.1 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat BTAD PF03704.17 KFP00819.1 - 1.6e-06 28.6 8.1 0.058 13.8 0.2 4.9 4 1 1 5 5 5 2 Bacterial transcriptional activator domain TPR_16 PF13432.6 KFP00819.1 - 3.1e-05 24.5 1.3 9.1 7.0 0.4 6.3 6 1 2 8 8 8 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFP00819.1 - 3.2e-05 23.5 10.9 0.18 11.5 0.0 5.7 7 0 0 7 7 5 2 TPR repeat TPR_9 PF13371.6 KFP00819.1 - 0.00015 21.9 3.1 1.4 9.1 0.0 5.4 5 1 1 6 6 6 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KFP00819.1 - 0.00033 20.3 6.3 0.0063 16.1 0.7 4.6 4 2 1 6 6 5 1 Bacterial type III secretion protein (HrpB1_HrpK) PPR PF01535.20 KFP00819.1 - 0.00043 20.3 0.0 25 5.4 0.0 5.4 6 0 0 6 6 4 0 PPR repeat TPR_7 PF13176.6 KFP00819.1 - 0.001 18.9 6.9 31 4.9 0.0 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat SNAP PF14938.6 KFP00819.1 - 0.005 16.3 13.9 0.009 15.5 1.1 4.0 3 2 0 3 3 3 1 Soluble NSF attachment protein, SNAP CorA PF01544.18 KFP00819.1 - 0.023 14.0 0.5 0.06 12.7 0.5 1.7 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ATP13 PF12921.7 KFP00819.1 - 0.033 14.1 0.1 3.4 7.5 0.0 3.4 2 1 1 3 3 3 0 Mitochondrial ATPase expression PMEI PF04043.15 KFP00819.1 - 0.042 14.2 8.6 0.17 12.2 0.5 3.8 3 1 0 3 3 3 0 Plant invertase/pectin methylesterase inhibitor PPR_2 PF13041.6 KFP00819.1 - 0.051 13.8 0.1 87 3.4 0.0 4.5 5 0 0 5 5 4 0 PPR repeat family HemY_N PF07219.13 KFP00819.1 - 0.06 13.5 4.2 33 4.7 0.0 4.6 4 0 0 4 4 4 0 HemY protein N-terminus TPR_17 PF13431.6 KFP00819.1 - 0.18 12.3 1.8 2.1e+02 2.6 0.0 5.4 6 0 0 6 6 4 0 Tetratricopeptide repeat DUF4919 PF16266.5 KFP00819.1 - 0.2 11.6 2.0 2.4 8.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4919) ASL_C PF08328.11 KFP00819.1 - 0.22 11.6 2.9 22 5.2 0.1 4.0 3 2 1 4 4 3 0 Adenylosuccinate lyase C-terminal TPR_10 PF13374.6 KFP00819.1 - 0.66 9.9 6.4 17 5.5 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat CCDC-167 PF15188.6 KFP00819.1 - 5 7.5 7.1 0.47 10.8 0.5 2.7 4 0 0 4 4 2 0 Coiled-coil domain-containing protein 167 Arf PF00025.21 KFP00820.1 - 4.9e-39 133.6 0.0 5.5e-39 133.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFP00820.1 - 1.7e-12 47.2 0.1 2e-12 46.9 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KFP00820.1 - 1.9e-11 44.2 0.0 3.3e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP00820.1 - 2.4e-10 40.3 0.0 2.8e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KFP00820.1 - 7.5e-06 25.5 0.0 1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP00820.1 - 0.00013 22.0 0.0 0.0002 21.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KFP00820.1 - 0.00018 20.8 0.2 0.0061 15.8 0.0 2.2 1 1 1 2 2 2 1 G-protein alpha subunit AAA_22 PF13401.6 KFP00820.1 - 0.00026 21.3 0.3 0.00092 19.5 0.3 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFP00820.1 - 0.0063 16.9 0.3 0.016 15.6 0.3 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KFP00820.1 - 0.019 15.4 0.1 0.049 14.0 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 KFP00820.1 - 0.057 13.2 0.3 1.9 8.2 0.1 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 KFP00820.1 - 0.064 13.8 0.1 0.088 13.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 KFP00820.1 - 0.069 12.7 0.8 1 8.9 0.1 2.2 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 KFP00820.1 - 0.085 12.5 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.12 KFP00820.1 - 0.12 12.2 0.7 2.4 8.0 0.1 2.1 1 1 1 2 2 2 0 NACHT domain Homeodomain PF00046.29 KFP00821.1 - 1.3e-09 37.7 0.1 1.5e-09 37.5 0.1 1.1 1 0 0 1 1 1 1 Homeodomain Colicin_Pyocin PF01320.18 KFP00821.1 - 0.017 15.2 0.0 0.023 14.8 0.0 1.2 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein GlgS PF08971.11 KFP00821.1 - 0.13 12.4 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycogen synthesis protein Homez PF11569.8 KFP00821.1 - 0.13 11.7 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Kazal_1 PF00050.21 KFP00822.1 - 3.3e-14 52.6 5.0 3.5e-14 52.5 5.0 1.1 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KFP00822.1 - 1.5e-09 37.8 2.5 1.8e-09 37.5 2.5 1.2 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain DSPc PF00782.20 KFP00823.1 - 4.2e-45 152.8 0.1 5.5e-45 152.4 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP00823.1 - 6.2e-06 25.9 0.0 8.6e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 KFP00823.1 - 0.00014 22.4 0.0 0.0006 20.3 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain PTPlike_phytase PF14566.6 KFP00823.1 - 0.2 11.8 0.0 0.29 11.2 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Ank_5 PF13857.6 KFP00824.1 - 1.5e-108 353.4 39.2 4.2e-13 49.2 0.3 13.8 5 5 9 14 14 14 13 Ankyrin repeats (many copies) Ank PF00023.30 KFP00824.1 - 6.8e-103 333.0 48.6 8.8e-08 32.3 0.1 17.6 17 0 0 17 17 17 15 Ankyrin repeat Ank_4 PF13637.6 KFP00824.1 - 1.6e-102 334.7 43.8 3.2e-13 49.9 0.2 14.2 7 5 9 16 16 16 16 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP00824.1 - 2.7e-100 329.1 51.0 7.6e-15 55.3 0.3 10.3 4 3 6 11 11 11 11 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP00824.1 - 1.5e-86 273.9 30.6 7.7e-07 28.9 0.1 18.0 19 0 0 19 19 19 14 Ankyrin repeat PARP PF00644.20 KFP00824.1 - 6.5e-27 94.4 4.8 1.6e-24 86.6 4.8 2.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SAM_2 PF07647.17 KFP00824.1 - 8.3e-15 54.7 0.4 1.8e-14 53.6 0.4 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFP00824.1 - 3e-12 46.8 0.6 6.8e-12 45.6 0.6 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Vps39_1 PF10366.9 KFP00824.1 - 0.017 15.4 1.9 15 5.9 0.1 4.3 4 1 1 5 5 5 0 Vacuolar sorting protein 39 domain 1 LRR_8 PF13855.6 KFP00825.1 - 3.2e-29 100.5 41.8 2.9e-12 46.1 3.4 4.8 2 1 4 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 KFP00825.1 - 8.5e-22 76.9 17.7 7.9e-06 26.1 1.8 5.9 1 1 8 9 9 9 9 Leucine Rich repeats (2 copies) COR PF16095.5 KFP00825.1 - 3.2e-13 49.9 0.0 9.4e-13 48.4 0.0 1.7 1 1 0 1 1 1 1 C-terminal of Roc, COR, domain LRR_9 PF14580.6 KFP00825.1 - 6.1e-06 25.9 6.1 0.41 10.1 0.2 4.2 1 1 2 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 KFP00825.1 - 5.6e-05 23.2 25.4 4.1 8.3 0.6 9.0 9 0 0 9 9 9 2 Leucine Rich Repeat Roc PF08477.13 KFP00825.1 - 5.8e-05 23.3 0.0 0.037 14.3 0.0 2.5 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RsmF_methylt_CI PF17126.5 KFP00825.1 - 0.002 18.1 1.4 20 5.3 0.0 5.1 4 1 0 5 5 5 1 RsmF rRNA methyltransferase first C-terminal domain LRR_6 PF13516.6 KFP00825.1 - 0.13 12.4 15.7 28 5.1 0.0 6.2 6 0 0 6 6 6 0 Leucine Rich repeat RNase_T PF00929.24 KFP00826.1 - 2e-30 106.5 0.0 4.6e-30 105.3 0.0 1.6 2 0 0 2 2 2 1 Exonuclease SAP PF02037.27 KFP00826.1 - 1.3e-07 31.1 0.8 2.6e-07 30.3 0.8 1.5 1 0 0 1 1 1 1 SAP domain SEA PF01390.20 KFP00826.1 - 0.12 12.5 0.0 7.3 6.7 0.0 2.4 1 1 1 2 2 2 0 SEA domain CBM_21 PF03370.13 KFP00827.1 - 1.1e-31 109.3 1.1 2.2e-31 108.4 0.9 1.5 2 0 0 2 2 2 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KFP00827.1 - 4.7e-12 46.3 0.7 9.9e-12 45.3 0.7 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Ldl_recept_a PF00057.18 KFP00828.1 - 6.6e-45 151.0 97.7 2e-09 37.5 9.7 7.0 7 0 0 7 7 7 6 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 KFP00828.1 - 3.4e-20 72.2 6.9 4.4e-08 33.5 0.0 5.8 5 0 0 5 5 5 4 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 KFP00828.1 - 7.5e-12 45.3 33.6 9.4e-08 32.2 9.3 7.8 5 2 2 7 7 7 3 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFP00828.1 - 1.7e-08 34.2 7.9 5.3e-06 26.2 0.4 4.7 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF_CA PF07645.15 KFP00828.1 - 8.1e-08 32.4 3.7 8.1e-08 32.4 3.7 7.8 5 1 2 7 7 7 1 Calcium-binding EGF domain PMP22_Claudin PF00822.20 KFP00829.1 - 1.3e-13 51.2 0.0 1.7e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP00829.1 - 0.0017 18.1 5.7 0.01 15.6 5.0 2.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.12 KFP00829.1 - 0.038 13.6 0.7 0.53 9.9 0.2 2.3 1 1 1 2 2 2 0 SUR7/PalI family DUF202 PF02656.15 KFP00829.1 - 0.07 13.6 3.1 2.4 8.7 2.9 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Clc-like PF07062.12 KFP00829.1 - 0.079 12.4 0.0 0.079 12.4 0.0 1.9 3 0 0 3 3 3 0 Clc-like DUF872 PF05915.12 KFP00829.1 - 1 9.5 3.1 0.77 9.9 0.5 2.0 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF2892 PF11127.8 KFP00829.1 - 2.9 8.0 10.1 0.43 10.6 1.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2892) BiPBP_C PF06832.12 KFP00830.1 - 0.057 13.5 0.1 0.15 12.1 0.1 1.8 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family RnaseA PF00074.20 KFP00831.1 - 0.00023 21.6 0.1 0.00026 21.4 0.1 1.1 1 0 0 1 1 1 1 Pancreatic ribonuclease MyTH4 PF00784.17 KFP00831.1 - 0.082 13.4 0.1 0.085 13.3 0.1 1.0 1 0 0 1 1 1 0 MyTH4 domain Ribosomal_S3Ae PF01015.18 KFP00832.1 - 3.3e-99 330.5 6.5 3.8e-99 330.3 6.5 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 KFP00832.1 - 0.0049 16.4 0.2 0.026 14.1 0.1 2.2 1 1 1 2 2 2 1 Partial alpha/beta-hydrolase lipase region NLRC4_HD2 PF17776.1 KFP00832.1 - 0.0095 16.5 0.2 0.013 16.0 0.2 1.2 1 0 0 1 1 1 1 NLRC4 helical domain HD2 GatB_N PF02934.15 KFP00834.1 - 1e-101 339.9 0.0 1.5e-101 339.4 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KFP00834.1 - 9.7e-39 132.6 8.7 1.7e-38 131.8 8.7 1.4 1 0 0 1 1 1 1 GatB domain WD40 PF00400.32 KFP00835.1 - 3.1e-48 160.7 31.8 2.6e-07 31.2 0.1 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP00835.1 - 1.3e-14 54.3 6.4 0.09 13.1 0.0 7.0 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP00835.1 - 2.6e-13 49.5 18.4 0.027 13.1 0.1 7.0 4 2 4 8 8 8 6 Nucleoporin Nup120/160 F-box-like PF12937.7 KFP00835.1 - 4e-13 49.0 1.7 6.9e-13 48.3 1.7 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFP00835.1 - 1.3e-08 34.5 0.3 2.2e-08 33.8 0.3 1.4 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.6 KFP00835.1 - 0.00012 21.8 4.2 0.0015 18.1 1.9 3.3 2 1 0 2 2 2 1 PQQ-like domain Ge1_WD40 PF16529.5 KFP00835.1 - 0.00016 20.8 10.7 1 8.2 0.2 5.3 1 1 4 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFP00835.1 - 0.00062 19.2 0.4 0.41 9.9 0.0 2.3 1 1 1 2 2 2 2 WD40-like domain eIF2A PF08662.11 KFP00835.1 - 0.0034 17.3 0.3 0.72 9.7 0.1 2.5 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A CDtoxinA PF03498.14 KFP00835.1 - 0.0064 16.1 2.5 0.65 9.6 0.3 3.4 2 1 1 3 3 3 1 Cytolethal distending toxin A/C domain Hira PF07569.11 KFP00835.1 - 0.0099 15.6 2.9 12 5.5 0.0 4.8 2 2 4 6 6 6 0 TUP1-like enhancer of split PALB2_WD40 PF16756.5 KFP00835.1 - 0.037 13.0 8.5 0.49 9.3 0.1 4.9 2 2 3 6 6 6 0 Partner and localizer of BRCA2 WD40 domain Nop14 PF04147.12 KFP00835.1 - 0.072 11.3 19.4 0.097 10.9 19.4 1.1 1 0 0 1 1 1 0 Nop14-like family PQQ PF01011.21 KFP00835.1 - 0.079 12.9 0.0 1.6e+02 2.5 0.0 5.0 5 0 0 5 5 5 0 PQQ enzyme repeat BUD22 PF09073.10 KFP00835.1 - 5.2 6.3 22.3 7.3 5.8 22.3 1.1 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 KFP00835.1 - 6.8 6.4 21.7 11 5.7 21.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TMEM154 PF15102.6 KFP00836.1 - 5e-38 130.2 1.9 5.7e-38 130.0 1.9 1.1 1 0 0 1 1 1 1 TMEM154 protein family Orf78 PF06024.12 KFP00836.1 - 0.00012 22.3 0.0 0.00018 21.7 0.0 1.3 1 0 0 1 1 1 1 Orf78 (ac78) RIFIN PF02009.16 KFP00836.1 - 0.028 14.3 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 Rifin DUF4448 PF14610.6 KFP00836.1 - 0.054 13.3 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF2207 PF09972.9 KFP00836.1 - 0.17 10.6 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DDE_1 PF03184.19 KFP00837.1 - 1.5e-35 122.4 0.0 2.7e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFP00837.1 - 1.4e-20 73.0 0.0 2.5e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFP00837.1 - 9.8e-09 34.7 2.2 2.2e-08 33.6 2.2 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 KFP00837.1 - 0.0028 17.4 0.0 0.072 12.9 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_Tnp_1 PF01527.20 KFP00837.1 - 0.038 14.3 0.8 0.1 12.9 0.1 2.1 2 1 1 3 3 3 0 Transposase DDE_3 PF13358.6 KFP00837.1 - 0.11 12.2 0.0 7.7 6.3 0.0 2.3 2 0 0 2 2 2 0 DDE superfamily endonuclease CENP-B_dimeris PF09026.10 KFP00837.1 - 0.12 12.8 0.3 0.12 12.8 0.3 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain HTH_28 PF13518.6 KFP00837.1 - 0.19 11.9 0.0 3 8.0 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain Arfaptin PF06456.13 KFP00838.1 - 1.5e-81 273.3 9.0 2e-81 272.9 9.0 1.1 1 0 0 1 1 1 1 Arfaptin-like domain TPR_MLP1_2 PF07926.12 KFP00838.1 - 0.11 12.6 4.9 5.3 7.1 0.2 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein NHL PF01436.21 KFP00839.1 - 9.5e-52 170.5 19.0 8.9e-10 38.1 0.2 6.6 6 0 0 6 6 6 6 NHL repeat DUF5128 PF17170.4 KFP00839.1 - 1.5e-19 70.4 7.1 7.2e-08 32.0 0.5 3.9 2 2 1 3 3 3 3 6-bladed beta-propeller Filamin PF00630.19 KFP00839.1 - 1.1e-17 64.8 0.0 3.9e-17 63.0 0.0 2.0 2 0 0 2 2 1 1 Filamin/ABP280 repeat SGL PF08450.12 KFP00839.1 - 2.2e-11 43.8 3.7 0.00017 21.3 0.1 5.4 1 1 4 5 5 5 3 SMP-30/Gluconolactonase/LRE-like region zf-B_box PF00643.24 KFP00839.1 - 9.3e-11 41.7 3.3 9.3e-11 41.7 3.3 2.9 3 1 0 3 3 1 1 B-box zinc finger zf-RING_UBOX PF13445.6 KFP00839.1 - 5.9e-10 39.0 5.8 5.9e-10 39.0 5.8 2.5 2 1 1 3 3 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFP00839.1 - 2e-08 33.9 10.0 2e-08 33.9 10.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP00839.1 - 5.1e-08 32.6 10.2 5.1e-08 32.6 10.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP00839.1 - 1.2e-07 31.4 7.8 1.2e-07 31.4 7.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP00839.1 - 5.2e-07 29.5 8.5 5.2e-07 29.5 8.5 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFP00839.1 - 7e-07 29.5 9.6 7e-07 29.5 9.6 2.6 2 0 0 2 2 2 1 Ring finger domain DUF4934 PF16288.5 KFP00839.1 - 1.6e-06 27.9 1.4 0.057 13.3 0.3 3.4 2 1 1 3 3 3 3 Domain of unknown function (DUF4934) Prok-RING_4 PF14447.6 KFP00839.1 - 1.5e-05 24.7 8.8 1.5e-05 24.7 8.8 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFP00839.1 - 0.0001 22.4 11.1 0.0001 22.4 11.1 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KFP00839.1 - 0.0066 16.5 1.4 0.017 15.2 1.4 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Caskin-tail PF16632.5 KFP00839.1 - 0.011 16.2 0.5 0.024 15.0 0.5 1.6 1 0 0 1 1 1 0 C-terminal region of Caskin SBBP PF06739.11 KFP00839.1 - 0.011 15.7 2.2 0.58 10.2 0.4 3.4 4 0 0 4 4 3 0 Beta-propeller repeat Invasin_D3 PF09134.10 KFP00839.1 - 0.014 15.7 0.0 0.047 14.0 0.0 1.9 1 0 0 1 1 1 0 Invasin, domain 3 zf-RING_11 PF17123.5 KFP00839.1 - 0.032 14.0 3.9 0.089 12.6 3.9 1.8 1 0 0 1 1 1 0 RING-like zinc finger Ldl_recept_b PF00058.17 KFP00839.1 - 0.034 14.6 0.0 28 5.3 0.0 3.8 4 0 0 4 4 3 0 Low-density lipoprotein receptor repeat class B Cadherin_5 PF17892.1 KFP00839.1 - 0.21 11.6 0.8 0.48 10.4 0.0 2.1 2 0 0 2 2 1 0 Cadherin-like domain NPV_P10 PF05531.12 KFP00839.1 - 0.71 10.4 2.7 1.5 9.3 1.4 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein VCBS PF13517.6 KFP00839.1 - 1.6 9.4 7.6 20 5.9 0.0 4.4 2 1 3 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella zf-RING_10 PF16685.5 KFP00839.1 - 3.2 8.0 11.7 4.4 7.5 4.7 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 Mnd1 PF03962.15 KFP00840.1 - 2.2e-29 101.5 0.2 2.2e-29 101.5 0.2 2.4 3 0 0 3 3 3 1 Mnd1 HTH domain LZ3wCH PF18517.1 KFP00840.1 - 4.8e-24 84.2 0.9 4.8e-24 84.2 0.9 2.5 3 0 0 3 3 3 1 Leucine zipper with capping helix domain DivIC PF04977.15 KFP00840.1 - 1.1e-06 28.3 12.2 0.0012 18.6 1.4 3.4 1 1 2 3 3 3 3 Septum formation initiator Penicillinase_R PF03965.16 KFP00840.1 - 3.1e-06 27.5 1.6 4e-06 27.2 0.7 1.6 1 1 1 2 2 2 1 Penicillinase repressor GAS PF13851.6 KFP00840.1 - 0.036 13.4 11.4 0.06 12.7 11.4 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FapA PF03961.13 KFP00840.1 - 0.06 11.9 5.6 0.087 11.4 5.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A TrmB PF01978.19 KFP00840.1 - 0.082 12.8 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Allexi_40kDa PF05549.11 KFP00840.1 - 0.082 12.4 0.9 0.11 12.0 0.9 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein DsrD PF08679.11 KFP00840.1 - 0.085 13.1 0.1 0.085 13.1 0.1 2.3 2 1 1 3 3 3 0 Dissimilatory sulfite reductase D (DsrD) DUF5395 PF17373.2 KFP00840.1 - 0.099 13.3 1.0 14 6.4 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5395) SHE3 PF17078.5 KFP00840.1 - 0.15 11.8 8.2 0.24 11.1 8.2 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 ABC_tran_CTD PF16326.5 KFP00840.1 - 0.45 10.8 15.1 0.36 11.1 13.0 2.0 1 1 1 2 2 2 0 ABC transporter C-terminal domain ZapB PF06005.12 KFP00840.1 - 0.47 10.9 14.4 0.73 10.3 2.7 2.4 1 1 1 2 2 2 0 Cell division protein ZapB Atg14 PF10186.9 KFP00840.1 - 0.91 8.5 8.6 1.4 7.9 8.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KFP00840.1 - 0.99 8.2 18.0 0.23 10.3 2.8 2.3 2 1 1 3 3 3 0 Spc7 kinetochore protein APG6_N PF17675.1 KFP00840.1 - 5.5 7.5 15.9 13 6.4 15.9 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4140 PF13600.6 KFP00840.1 - 7.3 7.1 9.8 4.2 7.9 1.0 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) TMEM131_like PF12371.8 KFP00841.1 - 1.1e-16 60.8 0.7 8.4e-16 58.0 0.1 2.8 3 0 0 3 3 3 1 Transmembrane protein 131-like ASH PF15780.5 KFP00841.1 - 3.5e-09 36.8 0.0 1.5e-05 25.1 0.0 4.5 4 0 0 4 4 4 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin LRR_8 PF13855.6 KFP00842.1 - 7.8e-35 118.4 44.1 1.5e-14 53.5 8.5 7.8 4 2 4 8 8 8 8 Leucine rich repeat TIR PF01582.20 KFP00842.1 - 2.2e-23 83.0 0.9 3.6e-23 82.3 0.9 1.4 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 KFP00842.1 - 9.9e-17 61.6 0.1 5.2e-16 59.3 0.1 2.3 2 0 0 2 2 2 1 TIR domain LRR_4 PF12799.7 KFP00842.1 - 5.3e-15 55.3 52.9 0.0085 16.5 3.9 9.3 6 2 4 11 11 11 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP00842.1 - 3.6e-08 33.1 12.0 0.013 15.0 0.0 4.8 2 2 1 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 KFP00842.1 - 0.0019 18.5 45.5 0.14 12.8 0.5 11.6 10 4 0 10 10 10 3 Leucine Rich Repeat Phytochelatin_C PF09328.10 KFP00842.1 - 0.0098 15.2 0.3 2.3 7.5 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1984) DUF1863 PF08937.11 KFP00842.1 - 0.08 13.3 0.1 0.52 10.6 0.1 2.2 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) HemY_N PF07219.13 KFP00842.1 - 0.17 12.1 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 HemY protein N-terminus Fz PF01392.22 KFP00843.1 - 1.6e-29 102.8 2.8 3.7e-29 101.6 2.8 1.6 1 0 0 1 1 1 1 Fz domain NTR PF01759.21 KFP00843.1 - 3.5e-12 46.1 0.2 5.9e-12 45.3 0.2 1.4 1 0 0 1 1 1 1 UNC-6/NTR/C345C module TBP PF00352.21 KFP00843.1 - 0.17 11.9 0.0 13 5.8 0.0 2.3 2 0 0 2 2 2 0 Transcription factor TFIID (or TATA-binding protein, TBP) Cadherin PF00028.17 KFP00844.1 - 4.5e-128 418.1 15.0 2.3e-22 79.2 0.0 8.3 8 0 0 8 8 8 7 Cadherin domain Cadherin_3 PF16184.5 KFP00844.1 - 1.3e-15 57.3 10.9 0.0092 16.0 0.0 7.0 7 0 0 7 7 7 6 Cadherin-like Cadherin_2 PF08266.12 KFP00844.1 - 6.8e-13 48.3 0.0 0.34 10.8 0.0 7.4 7 1 0 7 7 7 5 Cadherin-like RET_CLD1 PF17756.1 KFP00844.1 - 1.3e-06 28.7 2.6 2.6 8.4 0.0 5.8 5 2 0 6 6 6 3 RET Cadherin like domain 1 Big_9 PF17963.1 KFP00844.1 - 4.9e-05 24.0 32.7 0.021 15.6 0.2 7.0 7 1 0 7 7 7 5 Bacterial Ig domain Cadherin_4 PF17803.1 KFP00844.1 - 0.0014 19.2 34.0 0.53 11.0 1.5 7.1 7 1 0 7 7 7 3 Bacterial cadherin-like domain WD40 PF00400.32 KFP00845.1 - 1.1e-40 136.9 20.8 2e-09 37.9 0.6 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP00845.1 - 1.5e-05 25.2 4.6 0.25 11.7 0.1 5.0 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KFP00845.1 - 6e-05 22.0 0.7 0.74 8.5 0.0 3.7 2 1 1 4 4 4 2 Nup133 N terminal like BBS2_Mid PF14783.6 KFP00845.1 - 0.0012 18.8 0.1 6.1 6.9 0.0 4.3 3 1 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 KFP00845.1 - 0.0035 16.1 4.1 0.51 8.9 0.4 3.8 1 1 3 4 4 4 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KFP00845.1 - 0.062 12.6 0.0 0.28 10.5 0.0 2.0 2 1 1 3 3 3 0 WD40-like domain Fibrinogen_C PF00147.18 KFP00846.1 - 3e-101 337.8 13.8 4.2e-101 337.4 13.8 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fib_alpha PF08702.10 KFP00846.1 - 1.3e-41 142.2 2.4 1.7e-41 141.8 2.4 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF1465 PF07323.12 KFP00846.1 - 0.0016 18.3 1.3 0.066 13.1 0.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1465) DUF5082 PF16888.5 KFP00846.1 - 0.0055 17.0 7.3 0.036 14.3 4.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) EF-hand_6 PF13405.6 KFP00846.1 - 0.11 12.5 0.3 0.9 9.6 0.5 2.4 2 0 0 2 2 2 0 EF-hand domain DUF1664 PF07889.12 KFP00846.1 - 0.14 12.2 1.9 0.5 10.4 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TRAF_BIRC3_bd PF16673.5 KFP00846.1 - 0.73 9.7 2.8 9.6 6.1 0.1 2.5 2 1 1 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Bacillus_HBL PF05791.11 KFP00846.1 - 0.75 9.6 6.8 2 8.2 1.4 2.5 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Baculo_PEP_C PF04513.12 KFP00846.1 - 0.84 9.7 2.5 15 5.6 0.6 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 KFP00847.1 - 4.4e-43 146.9 4.7 8.3e-43 146.0 4.7 1.5 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF2935 PF11155.8 KFP00847.1 - 0.00048 20.5 0.4 0.0018 18.6 0.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF2935) DUF4407 PF14362.6 KFP00847.1 - 0.0072 15.7 5.6 0.048 13.0 5.4 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) RMI1_N PF08585.12 KFP00847.1 - 0.01 15.6 1.0 0.013 15.3 1.0 1.2 1 0 0 1 1 1 0 RecQ mediated genome instability protein Spc7 PF08317.11 KFP00847.1 - 0.013 14.4 5.2 0.023 13.6 5.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein TcdB_N PF12918.7 KFP00847.1 - 0.022 15.1 2.4 0.08 13.2 2.4 2.0 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain BST2 PF16716.5 KFP00847.1 - 0.07 13.7 3.5 3.9 8.1 0.3 2.9 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 Apolipoprotein PF01442.18 KFP00847.1 - 0.1 12.4 1.2 0.2 11.5 1.2 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain HAUS-augmin3 PF14932.6 KFP00847.1 - 0.41 10.2 4.6 0.84 9.2 4.6 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF1664 PF07889.12 KFP00847.1 - 0.65 10.0 4.8 2.2 8.3 4.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 KFP00847.1 - 1.5 9.3 9.1 17 5.9 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 ING PF12998.7 KFP00847.1 - 1.6 9.3 8.9 5.8 7.6 2.6 2.5 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding AtuA PF07287.11 KFP00848.1 - 3.1e-95 318.9 0.0 3.7e-95 318.6 0.0 1.0 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA LRAT PF04970.13 KFP00849.1 - 3.6e-26 91.9 0.0 4.8e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Lecithin retinol acyltransferase RRM_1 PF00076.22 KFP00850.1 - 3.6e-37 126.0 1.4 2.8e-14 52.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DND1_DSRM PF14709.7 KFP00850.1 - 2.6e-25 88.5 0.1 7.2e-25 87.1 0.1 1.8 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 RRM_7 PF16367.5 KFP00850.1 - 1.9e-06 27.9 2.3 0.036 14.2 0.1 4.0 2 2 1 3 3 3 2 RNA recognition motif RRM_5 PF13893.6 KFP00850.1 - 0.05 13.2 0.1 12 5.5 0.1 2.6 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 7tm_1 PF00001.21 KFP00851.1 - 5.4e-55 186.6 14.2 7.1e-55 186.2 14.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP00851.1 - 3.5e-15 56.1 13.5 4.8e-15 55.6 13.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP00851.1 - 1.4e-06 28.2 7.6 1.4e-06 28.2 7.6 1.8 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP00851.1 - 3e-05 23.9 14.7 4.3e-05 23.4 14.7 1.2 1 0 0 1 1 1 1 Olfactory receptor DUF5409 PF17421.2 KFP00851.1 - 0.72 10.6 0.1 0.72 10.6 0.1 2.7 4 0 0 4 4 4 0 Family of unknown function (DUF5409) DUF4207 PF13904.6 KFP00852.1 - 0.069 12.8 98.4 0.65 9.6 60.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4207) Guanylate_cyc PF00211.20 KFP00853.1 - 8.1e-63 211.4 0.0 1.3e-62 210.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KFP00853.1 - 1.8e-45 155.1 6.2 9.4e-45 152.7 1.6 2.6 2 1 0 2 2 2 1 Heme NO binding associated HNOB PF07700.15 KFP00853.1 - 7.7e-07 29.2 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Haem-NO-binding Guanylate_cyc PF00211.20 KFP00854.1 - 7.9e-66 221.2 0.0 1.2e-65 220.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KFP00854.1 - 3.1e-57 193.5 0.0 6.8e-57 192.4 0.0 1.6 1 1 0 1 1 1 1 Heme NO binding associated HNOB PF07700.15 KFP00854.1 - 7e-55 185.4 0.0 1e-54 184.9 0.0 1.3 1 0 0 1 1 1 1 Haem-NO-binding Trp_dioxygenase PF03301.13 KFP00855.1 - 2e-164 547.0 6.7 2.4e-164 546.7 6.7 1.0 1 0 0 1 1 1 1 Tryptophan 2,3-dioxygenase Peptidase_C1 PF00112.23 KFP00856.1 - 1.9e-58 198.1 3.7 2.3e-58 197.9 3.7 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KFP00856.1 - 4.7e-07 28.9 0.2 0.0013 17.6 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Inhibitor_I29 PF08246.12 KFP00856.1 - 0.041 14.3 0.1 0.1 13.1 0.1 1.7 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) rve PF00665.26 KFP00857.1 - 4.8e-25 88.1 0.1 8.2e-25 87.3 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_Zn PF02022.19 KFP00857.1 - 1.3e-16 60.2 3.8 1.8e-16 59.8 2.5 2.0 2 0 0 2 2 2 1 Integrase Zinc binding domain RNase_H PF00075.24 KFP00857.1 - 4.1e-09 36.8 0.3 9.9e-09 35.5 0.0 1.8 2 1 0 2 2 2 1 RNase H DDE_Tnp_IS240 PF13610.6 KFP00857.1 - 0.0039 17.4 0.0 0.0061 16.8 0.0 1.3 1 0 0 1 1 1 1 DDE domain RVT_1 PF00078.27 KFP00858.1 - 1.4e-31 109.8 0.0 1.8e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 KFP00858.1 - 1.2e-07 31.4 0.7 2.4e-07 30.5 0.7 1.5 1 0 0 1 1 1 1 Reverse transcriptase thumb domain dUTPase PF00692.19 KFP00859.1 - 6.3e-18 64.7 0.0 1e-17 64.0 0.0 1.4 1 1 0 1 1 1 1 dUTPase RVP PF00077.20 KFP00859.1 - 0.01 16.1 0.2 0.026 14.8 0.0 1.8 2 1 0 2 2 2 0 Retroviral aspartyl protease Yae1_N PF09811.9 KFP00860.1 - 2.6e-14 52.6 68.2 1.9 8.2 20.7 7.0 2 2 0 2 2 2 1 Essential protein Yae1, N terminal CUB PF00431.20 KFP00861.1 - 1.1e-17 64.3 0.0 1.9e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 CUB domain PDGF PF00341.17 KFP00861.1 - 2.9e-13 49.9 12.0 4.6e-13 49.3 12.0 1.3 1 0 0 1 1 1 1 PDGF/VEGF domain Neur_chan_LBD PF02931.23 KFP00862.1 - 4.5e-53 179.9 0.2 5.7e-53 179.5 0.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP00862.1 - 6.1e-35 121.4 0.1 1.2e-34 120.5 0.1 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF3267 PF11667.8 KFP00862.1 - 0.0091 16.3 1.8 0.12 12.7 1.8 2.3 1 1 0 1 1 1 1 Putative zincin peptidase FAM198 PF15051.6 KFP00863.1 - 7.3e-144 478.5 0.5 8.8e-144 478.3 0.5 1.0 1 0 0 1 1 1 1 FAM198 protein TMEM144 PF07857.12 KFP00864.1 - 1.2e-126 422.2 14.2 1.4e-126 422.0 14.2 1.0 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 KFP00864.1 - 3.5e-12 46.3 12.0 4.4e-11 42.6 3.1 2.4 2 0 0 2 2 2 2 Sugar transport protein DUF3272 PF11676.8 KFP00864.1 - 0.093 13.0 1.2 3.5 7.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3272) Hormone_4 PF00220.17 KFP00864.1 - 3.1 8.0 4.9 0.69 10.0 0.6 2.1 2 0 0 2 2 2 0 Neurohypophysial hormones, N-terminal Domain LRR_8 PF13855.6 KFP00865.1 - 6e-44 147.6 30.3 8.1e-14 51.1 4.5 5.5 2 2 3 5 5 5 5 Leucine rich repeat 7tm_1 PF00001.21 KFP00865.1 - 3.2e-27 95.5 16.4 4.9e-27 94.9 16.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_5 PF13306.6 KFP00865.1 - 1.5e-19 70.3 6.4 8.1e-10 38.8 2.3 2.6 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFP00865.1 - 6.4e-18 64.6 32.3 8.4e-06 26.0 1.1 6.7 1 1 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP00865.1 - 4.9e-10 39.2 17.4 0.0001 21.9 2.9 4.0 1 1 3 4 4 4 3 Leucine-rich repeat Ldl_recept_a PF00057.18 KFP00865.1 - 1.3e-07 31.7 5.0 1.3e-07 31.7 5.0 2.4 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A LRRNT PF01462.18 KFP00865.1 - 0.00025 20.6 0.1 0.00059 19.4 0.1 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KFP00865.1 - 0.046 14.3 27.8 2.1 9.2 0.3 8.9 9 1 1 10 10 10 0 Leucine Rich Repeat LRR_6 PF13516.6 KFP00865.1 - 0.17 12.0 11.3 31 5.0 0.1 6.3 6 0 0 6 6 6 0 Leucine Rich repeat ETF_QO PF05187.13 KFP00866.1 - 3.5e-48 162.0 0.0 6e-48 161.3 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 KFP00866.1 - 5.5e-09 36.1 1.9 3.1e-05 23.7 0.9 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFP00866.1 - 3e-08 33.2 0.7 4.2e-05 22.8 1.1 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KFP00866.1 - 4.3e-08 32.7 0.0 1.5e-05 24.4 0.1 2.1 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 KFP00866.1 - 8.5e-07 29.1 0.1 5.7e-06 26.5 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFP00866.1 - 4.5e-06 26.1 0.0 5.9e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFP00866.1 - 1.7e-05 24.3 0.0 4e-05 23.0 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 KFP00866.1 - 6.3e-05 23.0 0.0 0.00026 21.0 0.1 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KFP00866.1 - 0.00011 21.4 0.1 0.00015 20.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 KFP00866.1 - 0.00014 20.7 0.4 0.00021 20.1 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KFP00866.1 - 0.00048 20.6 0.0 0.44 11.1 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFP00866.1 - 0.0026 17.0 0.2 0.0042 16.4 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KFP00866.1 - 0.0036 16.2 0.0 0.027 13.3 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.7 KFP00866.1 - 0.0069 15.8 0.1 0.01 15.2 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fer4_7 PF12838.7 KFP00866.1 - 0.027 15.1 0.9 0.06 14.0 0.5 1.8 2 0 0 2 2 1 0 4Fe-4S dicluster domain K_oxygenase PF13434.6 KFP00866.1 - 0.03 13.5 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 KFP00866.1 - 0.042 12.9 0.2 0.066 12.3 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KFP00866.1 - 0.044 13.1 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pro_isomerase PF00160.21 KFP00867.1 - 1.3e-48 165.2 0.4 1.5e-48 165.1 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FNIP_M PF14637.6 KFP00868.1 - 2.8e-91 305.6 0.6 4.8e-91 304.8 0.6 1.4 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain FNIP_C PF14638.6 KFP00868.1 - 4.3e-73 245.0 0.4 1.1e-72 243.6 0.4 1.7 1 0 0 1 1 1 1 Folliculin-interacting protein C-terminus FNIP_N PF14636.6 KFP00868.1 - 5.6e-27 95.6 2.2 5.6e-27 95.6 2.2 4.2 3 1 0 3 3 3 1 Folliculin-interacting protein N-terminus RasGEF_N PF00618.20 KFP00869.1 - 5.9e-13 49.0 0.2 1.9e-11 44.1 0.2 2.5 1 1 0 1 1 1 1 RasGEF N-terminal motif RA PF00788.23 KFP00869.1 - 4e-11 43.4 0.0 1.2e-10 41.9 0.0 1.9 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain cNMP_binding PF00027.29 KFP00869.1 - 8e-11 41.9 0.0 0.00016 21.7 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PDZ PF00595.24 KFP00869.1 - 1.4e-10 41.3 0.0 2.9e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP00869.1 - 6.1e-10 38.8 0.0 1.3e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP00869.1 - 9.7e-05 22.6 0.0 0.00029 21.1 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Ig_3 PF13927.6 KFP00870.1 - 1.3e-28 99.4 0.2 6.3e-16 58.8 0.1 2.9 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP00870.1 - 2.6e-26 91.5 0.0 4.9e-15 55.4 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP00870.1 - 4.8e-18 65.3 0.0 2.3e-08 34.3 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP00870.1 - 4.6e-17 62.0 0.1 2.4e-07 30.8 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain Kazal_2 PF07648.15 KFP00870.1 - 5.6e-08 32.8 6.1 5.6e-08 32.8 6.1 2.4 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain V-set PF07686.17 KFP00870.1 - 3e-06 27.4 2.2 0.1 12.8 0.1 4.3 3 1 0 3 3 3 2 Immunoglobulin V-set domain Kazal_1 PF00050.21 KFP00870.1 - 8.1e-05 22.6 7.5 0.00013 21.9 6.3 2.0 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.6 KFP00870.1 - 0.00046 20.6 4.0 0.0014 19.0 4.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP00870.1 - 0.00077 18.8 0.2 0.0032 16.9 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KFP00870.1 - 0.0018 18.0 0.5 0.035 14.0 0.2 3.0 2 0 0 2 2 2 1 EF-hand domain C1-set PF07654.15 KFP00870.1 - 0.0019 18.5 0.0 0.45 10.9 0.0 2.8 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFP00870.1 - 0.0047 16.5 0.0 0.61 9.7 0.0 3.0 2 0 0 2 2 2 1 Immunoglobulin domain SPARC_Ca_bdg PF10591.9 KFP00870.1 - 0.026 14.8 0.7 0.067 13.5 0.7 1.7 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region C2-set_2 PF08205.12 KFP00870.1 - 0.071 13.2 0.4 3.1 7.9 0.0 3.0 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain Gar1 PF04410.14 KFP00872.1 - 1.7e-44 151.3 1.1 2.3e-44 150.9 1.1 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Rrn6 PF10214.9 KFP00872.1 - 0.79 8.1 5.2 0.92 7.9 5.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor 7tm_1 PF00001.21 KFP00873.1 - 3.6e-54 183.8 20.6 4.6e-54 183.5 20.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP00873.1 - 4.2e-10 39.4 20.0 6.6e-10 38.8 20.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP00873.1 - 0.00013 21.7 14.0 0.00013 21.7 14.0 2.8 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Git3 PF11710.8 KFP00873.1 - 0.031 14.0 10.4 0.086 12.6 10.4 1.7 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 TRP PF06011.12 KFP00873.1 - 0.7 8.6 14.6 0.79 8.4 4.5 2.5 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel PLAC8 PF04749.17 KFP00873.1 - 1.8 9.6 9.9 1.9 9.6 0.0 3.0 3 1 0 3 3 3 0 PLAC8 family Tma16 PF11176.8 KFP00874.1 - 2.6e-46 157.1 6.6 3.2e-46 156.8 6.6 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 HipN PF18253.1 KFP00874.1 - 0.0075 15.9 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Hsp70-interacting protein N N-terminal domain Use1 PF09753.9 KFP00874.1 - 0.14 11.8 6.2 0.21 11.3 6.2 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 RINGv PF12906.7 KFP00875.1 - 6.4e-16 58.2 15.7 1.4e-15 57.1 15.7 1.6 1 0 0 1 1 1 1 RING-variant domain PDEase_I PF00233.19 KFP00876.1 - 1.1e-29 103.9 1.4 1.2e-29 103.8 1.4 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 KFP00876.1 - 0.049 13.8 0.2 0.054 13.7 0.2 1.1 1 0 0 1 1 1 0 HD domain Yae1_N PF09811.9 KFP00878.1 - 4.7e-17 61.4 61.8 1.8e+04 -26.7 61.8 5.8 1 1 0 1 1 1 0 Essential protein Yae1, N terminal TMEM192 PF14802.6 KFP00879.1 - 4e-85 284.7 3.1 4.5e-85 284.5 3.1 1.0 1 0 0 1 1 1 1 TMEM192 family Fig1 PF12351.8 KFP00879.1 - 0.077 12.9 0.3 0.14 12.1 0.3 1.4 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 DUF4389 PF14333.6 KFP00879.1 - 0.57 10.1 5.1 3.9 7.4 0.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4389) Kelch_1 PF01344.25 KFP00880.1 - 5.1e-88 288.5 27.1 1.7e-16 59.5 1.9 6.6 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 KFP00880.1 - 2e-40 135.8 4.1 9.4e-08 32.1 0.0 6.3 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.15 KFP00880.1 - 7.3e-32 108.1 10.2 9.1e-06 25.5 0.1 6.4 6 0 0 6 6 6 5 Kelch motif BTB PF00651.31 KFP00880.1 - 8.9e-32 109.6 0.1 1.9e-31 108.5 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.6 KFP00880.1 - 1.6e-30 104.8 16.0 8.1e-06 26.0 0.2 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain BACK PF07707.15 KFP00880.1 - 4.1e-30 103.9 1.5 1.4e-29 102.2 1.2 2.1 2 1 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 KFP00880.1 - 1.3e-22 79.5 7.1 0.00059 19.8 0.1 6.4 4 1 2 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP00880.1 - 0.00061 19.7 17.3 0.69 10.0 0.1 5.1 5 0 0 5 5 5 4 Kelch motif PQQ_3 PF13570.6 KFP00880.1 - 0.00071 20.0 12.3 0.46 11.0 0.0 5.2 5 0 0 5 5 5 2 PQQ-like domain DUF3342 PF11822.8 KFP00880.1 - 0.13 12.5 0.3 4 7.7 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3342) FA_hydroxylase PF04116.13 KFP00881.1 - 3.8e-27 95.2 15.9 3.8e-27 95.2 15.9 1.7 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF4886 PF16227.5 KFP00881.1 - 0.094 11.9 0.1 0.17 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4886) CLAMP PF14769.6 KFP00881.1 - 0.37 11.3 4.4 0.51 10.8 3.2 1.9 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 Peptidase_M14 PF00246.24 KFP00882.1 - 1.5e-63 215.4 0.0 1.8e-63 215.1 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 KFP00882.1 - 8e-16 58.1 0.0 1.2e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KFP00882.1 - 3e-07 30.3 0.0 5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 CarboxypepD_reg-like domain AstE_AspA PF04952.14 KFP00882.1 - 0.016 14.3 0.0 0.039 13.0 0.0 1.6 1 1 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family CUB PF00431.20 KFP00883.1 - 3e-189 616.6 5.3 1.5e-40 137.9 0.2 5.3 5 0 0 5 5 5 5 CUB domain Astacin PF01400.24 KFP00883.1 - 4e-73 245.1 0.1 9.8e-73 243.9 0.0 1.7 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) FXa_inhibition PF14670.6 KFP00883.1 - 1.2e-19 70.2 28.4 1.2e-09 38.3 9.8 3.0 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 KFP00883.1 - 2.8e-12 46.6 30.7 4.4e-07 30.0 8.5 2.9 2 0 0 2 2 2 2 Calcium-binding EGF domain cEGF PF12662.7 KFP00883.1 - 1.1e-09 38.1 7.9 4.1e-05 23.4 2.3 3.3 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF PF00008.27 KFP00883.1 - 3.5e-07 30.4 21.3 0.00065 20.0 6.7 2.9 2 0 0 2 2 2 2 EGF-like domain CUB_2 PF02408.20 KFP00883.1 - 1e-05 25.3 3.0 0.57 10.0 0.0 4.4 4 0 0 4 4 4 2 CUB-like domain EGF_3 PF12947.7 KFP00883.1 - 3.3e-05 24.0 24.8 0.00042 20.4 4.8 3.6 2 1 1 3 3 3 2 EGF domain hEGF PF12661.7 KFP00883.1 - 0.00028 21.4 19.9 0.068 13.8 5.5 3.1 2 0 0 2 2 2 2 Human growth factor-like EGF Peptidase_M10 PF00413.24 KFP00883.1 - 0.0023 17.8 0.1 0.72 9.7 0.0 2.6 2 0 0 2 2 2 1 Matrixin Reprolysin_4 PF13583.6 KFP00883.1 - 0.018 14.7 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like AWS PF17907.1 KFP00883.1 - 3.4 7.8 10.2 9 6.4 1.2 3.0 2 0 0 2 2 2 0 AWS domain SPARC_Ca_bdg PF10591.9 KFP00884.1 - 1.1e-33 115.9 1.6 2.2e-33 114.9 1.6 1.5 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Thyroglobulin_1 PF00086.18 KFP00884.1 - 1.4e-17 63.1 6.5 1.4e-17 63.1 6.5 3.2 4 0 0 4 4 4 1 Thyroglobulin type-1 repeat Kazal_2 PF07648.15 KFP00884.1 - 2.9e-13 49.7 16.2 1.8e-12 47.1 10.5 3.1 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFP00884.1 - 1.3e-05 25.1 7.0 1.3e-05 25.1 7.0 3.7 3 1 0 3 3 3 1 Kazal-type serine protease inhibitor domain Annexin PF00191.20 KFP00885.1 - 1.1e-81 268.8 8.5 3.3e-21 75.1 0.2 4.0 4 0 0 4 4 4 4 Annexin PIN_2 PF10130.9 KFP00887.1 - 0.046 14.0 0.3 0.086 13.1 0.2 1.5 1 1 0 1 1 1 0 PIN domain DUF2408 PF10303.9 KFP00887.1 - 0.29 11.7 6.0 0.51 10.9 6.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) zf-B_box PF00643.24 KFP00887.1 - 1.9 8.7 5.4 0.32 11.2 0.8 2.0 2 0 0 2 2 2 0 B-box zinc finger I-set PF07679.16 KFP00888.1 - 3.1e-109 357.3 0.0 1.6e-21 76.2 0.0 6.4 5 1 0 5 5 5 5 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP00888.1 - 8.2e-71 234.6 0.3 1.5e-14 54.3 0.0 7.3 6 1 0 6 6 6 5 Immunoglobulin domain Ig_2 PF13895.6 KFP00888.1 - 1.1e-52 176.3 1.1 5.3e-10 39.5 0.0 6.0 6 0 0 6 6 6 5 Immunoglobulin domain ig PF00047.25 KFP00888.1 - 6.6e-49 164.0 6.0 2.9e-09 37.0 0.0 6.1 6 0 0 6 6 6 5 Immunoglobulin domain V-set PF07686.17 KFP00888.1 - 6.2e-20 71.4 5.7 0.0044 17.2 0.0 8.5 5 5 0 5 5 5 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP00888.1 - 2e-14 53.4 1.9 0.025 14.6 0.0 6.5 5 2 0 5 5 5 5 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFP00888.1 - 2.3e-07 31.1 1.7 6 7.3 0.0 7.0 6 2 1 7 7 7 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFP00888.1 - 8.7e-07 29.1 0.0 7.4 6.9 0.0 5.7 5 0 0 5 5 5 1 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 KFP00888.1 - 2.4e-06 27.8 0.1 1 9.8 0.0 4.8 5 0 0 5 5 5 2 Immunoglobulin C1-set domain Ig_C17orf99 PF17736.1 KFP00888.1 - 6.6e-05 22.9 0.0 18 5.4 0.0 5.4 5 0 0 5 5 5 0 C17orf99 Ig domain Ig_6 PF18452.1 KFP00888.1 - 9.6e-05 21.9 0.2 0.051 13.1 0.0 3.8 4 0 0 4 4 4 1 Immunoglobulin domain Receptor_2B4 PF11465.8 KFP00888.1 - 0.00033 20.8 0.0 0.23 11.7 0.0 4.1 5 0 0 5 5 5 1 Natural killer cell receptor 2B4 C2-set PF05790.15 KFP00888.1 - 0.0048 17.1 0.4 8 6.7 0.1 4.2 4 0 0 4 4 4 1 Immunoglobulin C2-set domain PKD_3 PF16820.5 KFP00888.1 - 0.03 14.0 0.0 0.51 10.1 0.0 2.7 3 0 0 3 3 3 0 PKD-like domain adh_short_C2 PF13561.6 KFP00889.1 - 7.8e-62 208.9 0.4 9.5e-62 208.6 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFP00889.1 - 1.8e-55 187.4 1.3 2.1e-55 187.2 1.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFP00889.1 - 2.8e-17 63.2 1.1 7.2e-17 61.9 0.9 1.7 1 1 1 2 2 2 1 KR domain NAD_binding_10 PF13460.6 KFP00889.1 - 0.0014 18.5 0.2 0.002 18.1 0.2 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KFP00889.1 - 0.0043 17.3 0.1 0.0088 16.3 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KFP00889.1 - 0.0089 15.5 0.1 0.023 14.2 0.1 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KFP00889.1 - 0.11 12.5 0.1 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SH3_9 PF14604.6 KFP00890.1 - 2.4e-54 180.9 1.4 2.4e-15 56.1 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_1 PF00018.28 KFP00890.1 - 5e-50 166.9 1.9 4.1e-12 45.5 0.0 4.3 4 0 0 4 4 4 4 SH3 domain SH3_2 PF07653.17 KFP00890.1 - 1.8e-35 120.4 1.8 5.4e-09 35.6 0.1 4.4 4 0 0 4 4 4 4 Variant SH3 domain zf-C3HC4 PF00097.25 KFP00890.1 - 4.2e-09 36.1 7.0 8.1e-09 35.2 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP00890.1 - 5.7e-09 35.9 5.5 1.4e-08 34.6 5.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFP00890.1 - 7.7e-09 35.3 7.4 1.6e-08 34.2 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP00890.1 - 1.9e-08 34.5 7.6 4.1e-08 33.4 7.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFP00890.1 - 1.3e-06 28.2 6.6 2.4e-06 27.4 6.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFP00890.1 - 1.9e-06 27.6 8.8 3.5e-06 26.8 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFP00890.1 - 0.00011 22.3 7.6 0.00021 21.4 7.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KFP00890.1 - 0.00045 20.0 5.0 0.00045 20.0 5.0 1.7 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KFP00890.1 - 0.00078 19.3 8.3 0.0059 16.4 8.7 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KFP00890.1 - 0.0071 16.1 2.8 0.02 14.6 2.8 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-Nse PF11789.8 KFP00890.1 - 0.13 12.1 2.4 0.3 10.9 2.4 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.20 KFP00890.1 - 0.13 12.1 5.2 0.25 11.1 5.2 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.7 KFP00890.1 - 0.36 11.2 3.7 0.88 9.9 3.7 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain Trm112p PF03966.16 KFP00890.1 - 1.8 9.2 5.9 5.4 7.7 5.9 1.9 1 0 0 1 1 1 0 Trm112p-like protein RVT_1 PF00078.27 KFP00891.1 - 0.1 12.1 0.0 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Voltage_CLC PF00654.20 KFP00892.1 - 6.3e-104 348.0 21.5 1e-103 347.4 21.5 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 KFP00892.1 - 8.3e-14 51.8 0.7 7.1e-07 29.6 0.1 2.5 2 0 0 2 2 2 2 CBS domain DUF2228 PF10228.9 KFP00893.1 - 3.6e-105 351.2 0.9 6.1e-105 350.5 0.9 1.3 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2228) I-set PF07679.16 KFP00894.1 - 1.3e-14 54.0 0.0 2.9e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP00894.1 - 4.4e-14 52.9 0.1 1.1e-13 51.6 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP00894.1 - 1.7e-11 44.1 0.1 3.4e-11 43.2 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP00894.1 - 4.8e-09 36.4 0.1 8.7e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP00894.1 - 8e-06 26.0 0.6 0.0025 17.9 0.1 2.6 1 1 0 2 2 2 2 Immunoglobulin V-set domain DUF5362 PF17319.2 KFP00894.1 - 0.013 15.3 0.8 0.027 14.3 0.7 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5362) DUF4446 PF14584.6 KFP00894.1 - 0.098 12.6 0.8 0.19 11.7 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Ig_C17orf99 PF17736.1 KFP00894.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 C17orf99 Ig domain TSP_1 PF00090.19 KFP00895.1 - 8.5e-28 96.3 71.5 6.3e-08 32.7 4.9 7.1 5 1 1 6 6 6 6 Thrombospondin type 1 domain ADAM_spacer1 PF05986.14 KFP00895.1 - 2e-17 63.3 0.0 3e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 PLAC PF08686.11 KFP00895.1 - 4e-10 40.3 14.9 2e-09 38.0 14.9 2.4 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Neur_chan_LBD PF02931.23 KFP00896.1 - 7e-74 247.9 1.1 9.2e-74 247.5 1.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP00896.1 - 6.3e-65 219.6 0.0 7.9e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region SUR7 PF06687.12 KFP00896.1 - 0.088 12.4 2.3 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 SUR7/PalI family DUF2417 PF10329.9 KFP00896.1 - 1.4 8.2 5.0 1 8.7 2.7 1.8 2 0 0 2 2 2 0 Region of unknown function (DUF2417) tRNA_bind_3 PF17176.4 KFP00897.1 - 0.0092 16.3 2.3 0.027 14.8 0.2 2.8 2 1 0 2 2 2 1 tRNA-binding domain Apolipoprotein PF01442.18 KFP00897.1 - 0.16 11.9 28.9 0.48 10.3 20.1 2.9 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain GLE1 PF07817.13 KFP00897.1 - 1 8.5 16.8 0.11 11.7 3.6 3.7 2 1 2 4 4 4 0 GLE1-like protein Baculo_PEP_C PF04513.12 KFP00897.1 - 1.2 9.1 23.3 1.3 9.1 1.0 4.1 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 KFP00897.1 - 1.3 9.2 35.6 1.4 9.1 0.4 3.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family TraF_2 PF13729.6 KFP00897.1 - 7 5.9 6.9 1.4 8.3 1.7 2.4 2 2 1 3 3 3 0 F plasmid transfer operon, TraF, protein Cyclin_N PF00134.23 KFP00898.1 - 3.3e-42 143.2 0.6 5.8e-41 139.2 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP00898.1 - 5.9e-32 110.3 2.0 1.1e-31 109.3 1.2 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain RNF111_N PF15303.6 KFP00899.1 - 1.1e-127 425.6 23.4 1.1e-127 425.6 23.4 2.5 2 1 0 2 2 1 1 E3 ubiquitin-protein ligase Arkadia N-terminus zf-RING_2 PF13639.6 KFP00899.1 - 7.6e-13 48.6 6.8 7.6e-13 48.6 6.8 3.3 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP00899.1 - 4.5e-09 36.0 6.6 4.5e-09 36.0 6.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFP00899.1 - 8.2e-08 31.9 2.6 8.2e-08 31.9 2.6 2.7 3 0 0 3 3 3 1 RING-like zinc finger zf-rbx1 PF12678.7 KFP00899.1 - 3.6e-07 30.4 4.1 3.6e-07 30.4 4.1 3.0 3 0 0 3 3 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KFP00899.1 - 9.2e-07 28.6 4.5 2.5e-06 27.2 4.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP00899.1 - 1.8e-06 27.7 5.9 1.8e-06 27.7 5.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP00899.1 - 3.3e-05 23.8 3.8 3.3e-05 23.8 3.8 2.5 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP00899.1 - 0.00029 20.7 7.0 0.00029 20.6 4.6 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFP00899.1 - 0.063 13.3 5.8 0.14 12.2 3.9 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 KFP00899.1 - 0.56 10.4 6.6 2.2 8.5 6.5 2.2 1 1 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 KFP00899.1 - 1.3 8.7 9.7 0.068 12.8 3.4 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type RRM_1 PF00076.22 KFP00900.1 - 2.2e-11 43.4 0.0 4.9e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP00900.1 - 2.7e-08 33.5 0.0 5.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Reprolysin_2 PF13574.6 KFP00901.1 - 4.9e-34 117.9 0.2 4.9e-34 117.9 0.2 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFP00901.1 - 1.9e-32 113.0 2.0 1.7e-31 109.9 0.2 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFP00901.1 - 1.1e-27 97.0 0.0 2.5e-27 95.8 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP00901.1 - 5.7e-16 58.8 0.3 1.1e-15 57.8 0.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 KFP00901.1 - 4.6e-14 53.0 31.8 4.6e-14 53.0 31.8 3.8 3 1 1 4 4 4 1 Disintegrin Pep_M12B_propep PF01562.19 KFP00901.1 - 1.4e-12 48.0 1.1 3e-12 46.9 1.1 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 KFP00901.1 - 1.2e-05 25.3 1.1 1.2e-05 25.3 1.1 2.9 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Peptidase_M66 PF10462.9 KFP00901.1 - 0.019 13.9 0.2 0.048 12.6 0.2 1.6 1 0 0 1 1 1 0 Peptidase M66 UPF0370 PF13980.6 KFP00901.1 - 0.023 14.7 0.3 0.055 13.5 0.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) Lipase PF00151.19 KFP00902.1 - 1.7e-120 402.3 0.1 2.4e-120 401.9 0.1 1.2 1 0 0 1 1 1 1 Lipase PLAT PF01477.23 KFP00902.1 - 1.1e-20 74.4 1.2 2.1e-20 73.4 1.2 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain Abhydrolase_6 PF12697.7 KFP00902.1 - 0.00012 22.7 0.2 0.00018 22.2 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family GSG-1 PF07803.11 KFP00902.1 - 0.091 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 GSG1-like protein MIP PF00230.20 KFP00903.1 - 3.4e-52 177.4 13.5 4.1e-52 177.1 13.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein Aldedh PF00171.22 KFP00904.1 - 3.5e-179 596.2 0.0 3.9e-179 596.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KFP00904.1 - 0.014 14.9 0.1 4 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) LuxC PF05893.14 KFP00904.1 - 0.17 10.9 0.0 11 5.0 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) SlyX PF04102.12 KFP00905.1 - 0.0013 19.3 4.4 0.0013 19.3 4.4 6.8 3 2 4 7 7 7 1 SlyX DUF4349 PF14257.6 KFP00905.1 - 0.0064 16.0 8.1 0.0064 16.0 8.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4349) BLOC1_2 PF10046.9 KFP00905.1 - 0.0091 16.3 4.0 0.0091 16.3 4.0 5.0 2 1 2 5 5 5 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4195 PF13836.6 KFP00906.1 - 3.5e-42 144.6 10.6 3.5e-42 144.6 10.6 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4195) zf-Di19 PF05605.12 KFP00906.1 - 0.0021 18.3 1.8 0.0021 18.3 1.8 7.6 6 2 1 7 7 7 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KFP00906.1 - 0.0055 17.4 80.6 0.099 13.5 0.2 9.6 10 0 0 10 10 10 6 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFP00906.1 - 0.0086 16.1 0.1 0.0086 16.1 0.1 8.3 8 1 0 8 8 8 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP00906.1 - 0.011 16.1 0.2 0.011 16.1 0.2 9.9 9 2 1 10 10 10 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFP00906.1 - 0.043 14.1 0.3 0.043 14.1 0.3 7.6 7 1 0 7 7 7 0 Zinc-finger double-stranded RNA-binding SelR PF01641.18 KFP00906.1 - 0.066 13.3 0.2 0.066 13.3 0.2 4.1 4 1 0 4 4 4 0 SelR domain zf-met PF12874.7 KFP00906.1 - 0.23 11.9 0.2 0.23 11.9 0.2 7.2 7 0 0 7 7 7 0 Zinc-finger of C2H2 type TPH PF13868.6 KFP00907.1 - 1.8e-83 280.0 152.8 1.8e-83 280.0 152.8 2.0 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain RFX_DNA_binding PF02257.15 KFP00908.1 - 8e-28 96.9 0.0 7.5e-26 90.6 0.0 2.4 2 0 0 2 2 2 1 RFX DNA-binding domain Pox_D5 PF03288.16 KFP00908.1 - 0.0002 21.8 0.1 0.00049 20.5 0.1 1.6 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 KFP00908.1 - 0.017 15.1 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4111 PF13427.6 KFP00908.1 - 0.089 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) HECT PF00632.25 KFP00909.1 - 1.1e-101 340.3 0.1 2e-101 339.5 0.1 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KFP00909.1 - 1.1e-47 159.8 21.4 3.6e-13 49.4 0.7 5.2 4 0 0 4 4 4 4 WW domain C2 PF00168.30 KFP00909.1 - 1.5e-22 79.8 0.0 3.6e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain 2OG-FeII_Oxy_4 PF13661.6 KFP00909.1 - 0.11 13.2 0.0 0.27 11.9 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily WW_1 PF18507.1 KFP00909.1 - 0.32 10.7 3.3 24 4.7 0.0 3.6 4 0 0 4 4 4 0 WW domain fn3 PF00041.21 KFP00910.1 - 4.2e-63 209.7 5.0 2.5e-12 46.9 0.1 5.6 5 0 0 5 5 5 5 Fibronectin type III domain I-set PF07679.16 KFP00910.1 - 1.3e-56 188.6 0.0 3.8e-15 55.7 0.0 5.7 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP00910.1 - 6.4e-55 183.7 1.4 3.2e-13 50.1 0.0 5.1 5 0 0 5 5 4 4 Immunoglobulin domain ig PF00047.25 KFP00910.1 - 6.9e-34 115.9 0.0 1.2e-07 31.8 0.0 4.5 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFP00910.1 - 1.5e-33 114.9 0.5 1.2e-07 31.9 0.0 5.2 5 0 0 5 5 5 4 Immunoglobulin domain V-set PF07686.17 KFP00910.1 - 9.6e-16 57.9 10.2 0.1 12.8 0.0 8.7 6 4 4 10 10 9 5 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 KFP00910.1 - 2.2e-15 57.0 7.5 0.00066 20.2 0.1 6.2 5 1 0 5 5 5 3 Purple acid Phosphatase, N-terminal domain C2-set_2 PF08205.12 KFP00910.1 - 3.1e-11 43.2 0.2 0.011 15.8 0.0 4.7 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain fn3_2 PF16893.5 KFP00910.1 - 3.1e-09 36.8 0.0 0.0028 17.7 0.0 4.5 4 0 0 4 4 4 2 Fibronectin type III domain Ig_6 PF18452.1 KFP00910.1 - 2.7e-06 26.8 0.0 0.018 14.6 0.0 4.0 4 0 0 4 4 4 1 Immunoglobulin domain SusE PF14292.6 KFP00910.1 - 1e-05 25.7 0.3 0.41 10.9 0.0 4.8 4 0 0 4 4 4 1 SusE outer membrane protein Ig_4 PF16680.5 KFP00910.1 - 1.4e-05 25.3 0.1 0.9 9.8 0.0 4.4 4 1 0 4 4 3 1 T-cell surface glycoprotein CD3 delta chain Interfer-bind PF09294.10 KFP00910.1 - 0.00018 21.8 0.3 29 5.0 0.0 4.6 4 0 0 4 4 4 0 Interferon-alpha/beta receptor, fibronectin type III fn3_4 PF16794.5 KFP00910.1 - 0.00021 21.2 2.0 0.035 14.0 0.0 4.4 5 0 0 5 5 5 1 Fibronectin-III type domain C1-set PF07654.15 KFP00910.1 - 0.00064 20.1 0.5 0.15 12.4 0.0 4.6 6 0 0 6 6 5 1 Immunoglobulin C1-set domain DUF2369 PF10179.9 KFP00910.1 - 0.00099 19.4 0.0 26 5.3 0.0 5.2 5 0 0 5 5 5 0 Uncharacterised conserved protein (DUF2369) Izumo-Ig PF16706.5 KFP00910.1 - 0.005 16.9 1.1 3.2 7.9 0.0 4.4 5 0 0 5 5 4 1 Izumo-like Immunoglobulin domain Syndecan PF01034.20 KFP00910.1 - 0.01 15.8 0.4 0.21 11.5 1.0 2.4 2 0 0 2 2 2 1 Syndecan domain Adeno_E3_CR2 PF02439.15 KFP00910.1 - 0.018 14.8 5.2 0.038 13.8 5.2 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Glycoprotein_G PF00802.19 KFP00910.1 - 0.06 12.7 0.7 0.11 11.8 0.7 1.4 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G PHD PF00628.29 KFP00911.1 - 6.9e-07 29.1 5.7 1.2e-06 28.3 5.7 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 KFP00911.1 - 0.0024 17.8 1.1 0.0053 16.7 1.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 KFP00911.1 - 0.05 13.9 4.5 0.1 13.0 4.5 1.5 1 0 0 1 1 1 0 Ring finger domain PHD_4 PF16866.5 KFP00911.1 - 0.28 11.3 4.8 0.92 9.6 4.8 2.0 1 1 0 1 1 1 0 PHD-finger TP53IP5 PF15331.6 KFP00911.1 - 0.33 11.1 2.1 0.54 10.4 2.1 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 zf-RING_11 PF17123.5 KFP00911.1 - 0.62 9.9 4.6 1.2 8.9 4.6 1.5 1 0 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 KFP00911.1 - 1.5 9.0 5.1 0.95 9.7 2.7 1.8 2 0 0 2 2 2 0 FANCL C-terminal domain Macoilin PF09726.9 KFP00911.1 - 6.6 5.1 9.6 8.2 4.8 9.6 1.0 1 0 0 1 1 1 0 Macoilin family TPR_1 PF00515.28 KFP00912.1 - 1.6e-13 49.9 6.2 3.5e-06 26.6 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFP00912.1 - 1.3e-11 43.6 5.3 0.00079 19.4 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFP00912.1 - 6.2e-09 35.4 5.9 5.4e-05 22.8 1.1 2.7 3 0 0 3 3 3 2 TPR repeat TPR_9 PF13371.6 KFP00912.1 - 2e-07 31.0 0.1 0.013 15.6 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP00912.1 - 2.8e-07 30.2 4.0 0.087 13.1 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFP00912.1 - 7e-05 23.0 4.0 0.0025 18.1 2.1 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFP00912.1 - 0.0047 17.6 1.1 3.2 8.5 0.4 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 KFP00912.1 - 0.055 12.9 0.4 33 4.0 0.0 3.6 4 0 0 4 4 4 0 SHNi-TPR TPR_19 PF14559.6 KFP00912.1 - 0.13 12.8 3.2 1 10.0 1.2 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat CDC45 PF02724.14 KFP00912.1 - 0.19 10.0 12.3 0.019 13.3 8.2 1.3 2 0 0 2 2 2 0 CDC45-like protein DUF763 PF05559.11 KFP00912.1 - 2.5 7.2 8.2 3.8 6.6 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF763) TPR_17 PF13431.6 KFP00912.1 - 2.6 8.6 5.6 35 5.1 1.5 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat WDCP PF15390.6 KFP00912.1 - 3.6 5.8 12.4 4.7 5.5 12.4 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family HbrB PF08539.11 KFP00913.1 - 0.022 14.7 0.2 0.022 14.7 0.2 2.8 3 0 0 3 3 3 0 HbrB-like Baculo_PEP_C PF04513.12 KFP00913.1 - 0.12 12.5 0.6 2.5 8.1 0.4 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KFP00913.1 - 0.76 9.8 25.0 0.11 12.6 4.3 4.4 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) Glyco_transf_22 PF03901.17 KFP00914.1 - 1e-109 367.6 28.9 1.3e-109 367.3 28.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF2368 PF10166.9 KFP00914.1 - 3.3 7.3 4.4 4.1 7.0 0.6 2.4 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) Ras PF00071.22 KFP00915.1 - 7.6e-58 194.7 0.0 9e-58 194.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP00915.1 - 3.1e-31 108.1 0.0 5e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP00915.1 - 8e-12 44.9 0.0 1.1e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFP00915.1 - 0.00012 22.0 0.2 0.24 11.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFP00915.1 - 0.00029 20.5 0.0 0.00067 19.2 0.0 1.7 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFP00915.1 - 0.00067 19.7 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP-grasp_5 PF13549.6 KFP00915.1 - 0.074 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain TPP_enzyme_M PF00205.22 KFP00915.1 - 0.087 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Ribosomal_L24e PF01246.20 KFP00916.1 - 8.8e-14 51.5 6.2 8.8e-14 51.5 6.2 2.1 2 0 0 2 2 2 1 Ribosomal protein L24e DUF1091 PF06477.13 KFP00916.1 - 0.089 13.3 1.1 0.11 12.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1091) CK1gamma_C PF12605.8 KFP00917.1 - 4.9e-31 107.8 4.7 1e-30 106.8 4.7 1.5 1 0 0 1 1 1 1 Casein kinase 1 gamma C terminal Pkinase PF00069.25 KFP00917.1 - 4.1e-26 91.9 0.0 5.4e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP00917.1 - 1.7e-14 53.8 0.0 2.2e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP00917.1 - 2.1e-08 33.4 0.2 3.1e-08 32.8 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase PIP49_C PF12260.8 KFP00917.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 ASCH PF04266.14 KFP00918.1 - 3.2e-21 75.9 0.0 6.5e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 ASCH domain zf-C2HC5 PF06221.13 KFP00918.1 - 2.6e-10 40.1 10.7 6.4e-10 38.9 10.7 1.7 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type TraB PF01963.17 KFP00920.1 - 1.6e-23 84.0 0.0 1.7e-23 83.8 0.0 1.0 1 0 0 1 1 1 1 TraB family TraB PF01963.17 KFP00921.1 - 7.2e-38 131.0 0.0 8.2e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 TraB family SSF PF00474.17 KFP00922.1 - 1e-147 492.3 23.6 1.4e-147 491.8 23.6 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family SPATA6 PF14909.6 KFP00923.1 - 3.2e-53 179.6 0.0 5.7e-53 178.8 0.0 1.4 1 0 0 1 1 1 1 Spermatogenesis-assoc protein 6 BEN PF10523.9 KFP00924.1 - 1.1e-15 57.7 0.1 2.5e-15 56.5 0.1 1.7 1 0 0 1 1 1 1 BEN domain T4SS PF07996.11 KFP00924.1 - 0.0049 17.3 1.3 0.0086 16.5 0.6 1.7 2 0 0 2 2 2 1 Type IV secretion system proteins Sec8_exocyst PF04048.14 KFP00924.1 - 0.03 14.2 2.4 0.074 12.9 2.4 1.6 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain PIN_12 PF16289.5 KFP00924.1 - 0.32 11.5 3.8 0.096 13.2 0.5 2.0 2 0 0 2 2 2 0 PIN domain TSNAXIP1_N PF15739.5 KFP00924.1 - 1.3 9.5 10.4 0.54 10.6 6.5 2.3 2 1 1 3 3 3 0 Translin-associated factor X-interacting N-terminus Pepdidase_M14_N PF18027.1 KFP00925.1 - 1.8e-06 28.2 0.0 2.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain RRM_1 PF00076.22 KFP00926.1 - 3.7e-66 218.9 0.1 4.1e-21 74.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP00926.1 - 8.4e-13 48.0 0.0 3.2e-05 23.5 0.0 3.1 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KFP00926.1 - 3.7e-05 23.9 0.0 0.49 10.6 0.0 2.8 3 0 0 3 3 3 2 BRCA1-associated protein 2 RRM_occluded PF16842.5 KFP00926.1 - 0.0003 20.6 0.0 1.1 9.2 0.0 3.4 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 KFP00926.1 - 0.0026 17.8 0.0 0.43 10.7 0.0 2.5 2 0 0 2 2 2 1 RNA binding motif RRM_7 PF16367.5 KFP00926.1 - 0.0051 16.9 0.0 1.1 9.4 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif RNA_bind PF08675.11 KFP00926.1 - 0.06 13.4 0.0 2.7 8.1 0.0 2.7 2 1 0 2 2 2 0 RNA binding domain RRM_2 PF04059.12 KFP00926.1 - 0.14 12.4 0.1 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif 2 UBX PF00789.20 KFP00927.1 - 1.2e-20 73.5 0.1 3.8e-20 71.9 0.1 1.9 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 KFP00927.1 - 4e-05 23.3 0.8 9.6e-05 22.1 0.8 1.7 1 0 0 1 1 1 1 UBA-like domain ubiquitin PF00240.23 KFP00927.1 - 0.0025 17.6 0.1 0.6 9.9 0.0 3.1 3 0 0 3 3 3 1 Ubiquitin family Borrelia_P83 PF05262.11 KFP00927.1 - 0.3 9.5 6.1 0.43 9.0 6.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein AAA_23 PF13476.6 KFP00927.1 - 2 8.9 7.9 3.9 7.9 7.9 1.4 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.7 KFP00928.1 - 3e-30 104.7 3.4 8.8e-13 48.7 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP00928.1 - 1.3e-20 73.2 1.2 2.2e-11 43.7 0.1 3.4 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP00928.1 - 1.1e-15 57.7 0.1 2.2e-08 34.5 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KFP00928.1 - 1.4e-14 53.8 1.3 2.9e-05 24.3 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 KFP00928.1 - 1.9e-11 43.1 0.4 0.00023 21.3 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat DUF1843 PF08898.10 KFP00928.1 - 0.063 13.8 0.1 0.33 11.5 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) zf-RING_2 PF13639.6 KFP00929.1 - 3.5e-12 46.4 5.6 4.8e-12 46.0 5.6 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFP00929.1 - 2.2e-11 43.3 4.6 2.2e-11 43.3 4.6 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KFP00929.1 - 9.1e-08 32.0 2.8 1.7e-07 31.2 2.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFP00929.1 - 4.5e-07 29.6 6.0 6.5e-07 29.1 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFP00929.1 - 2.3e-06 27.8 7.9 1.2e-05 25.4 7.9 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KFP00929.1 - 3e-06 27.0 2.2 4.3e-06 26.5 2.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP00929.1 - 3.6e-06 26.7 3.5 5.7e-06 26.1 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP00929.1 - 3e-05 23.9 1.7 4.8e-05 23.2 1.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KFP00929.1 - 5.1e-05 22.8 2.7 8.4e-05 22.1 2.7 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KFP00929.1 - 0.00012 21.9 2.2 0.00018 21.3 2.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFP00929.1 - 0.062 13.5 3.7 0.11 12.6 3.7 1.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KFP00929.1 - 0.084 12.8 1.6 0.13 12.1 1.6 1.2 1 0 0 1 1 1 0 zf-RING of BARD1-type protein BCDHK_Adom3 PF10436.9 KFP00929.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase zf-C3H2C3 PF17122.5 KFP00929.1 - 0.15 12.1 3.9 0.37 10.9 3.9 1.8 1 1 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 KFP00929.1 - 0.19 11.9 8.2 4.4 7.5 8.2 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KFP00929.1 - 0.36 10.9 6.9 4.1 7.5 7.2 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3808 PF10300.9 KFP00930.1 - 2.8e-145 484.7 12.7 8.2e-145 483.2 8.8 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_16 PF13432.6 KFP00930.1 - 9.3e-09 35.8 3.9 0.002 18.7 0.0 5.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFP00930.1 - 1.8e-08 34.6 4.5 2.2e-06 27.9 0.6 3.4 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP00930.1 - 0.00011 22.8 3.6 0.056 14.3 0.1 4.1 4 1 1 5 5 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFP00930.1 - 0.00038 20.4 13.2 0.018 15.1 1.5 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFP00930.1 - 0.00041 20.1 4.9 0.0029 17.4 0.4 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFP00930.1 - 0.00076 20.0 2.5 0.027 15.1 1.0 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFP00930.1 - 0.0014 18.7 5.8 0.34 11.2 0.6 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFP00930.1 - 0.0015 18.2 9.2 0.32 10.9 1.7 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 KFP00930.1 - 0.0098 16.4 0.0 0.6 10.9 0.0 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFP00930.1 - 0.01 15.8 1.3 0.038 14.0 0.3 2.6 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP00930.1 - 0.011 16.2 12.7 0.079 13.5 1.4 4.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP00930.1 - 0.018 14.4 3.7 0.16 11.3 0.4 2.7 3 0 0 3 3 3 0 MalT-like TPR region SOAR PF16533.5 KFP00930.1 - 3.1 7.8 5.1 1 9.4 0.0 2.6 3 0 0 3 3 3 0 STIM1 Orai1-activating region EF-hand_4 PF12763.7 KFP00931.1 - 2.2e-41 140.0 0.0 1.7e-23 82.5 0.0 3.7 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KFP00931.1 - 5e-12 44.5 5.0 0.0022 17.4 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFP00931.1 - 2.1e-07 30.3 2.4 0.42 10.7 0.0 4.9 5 0 0 5 5 4 2 EF-hand domain EF-hand_7 PF13499.6 KFP00931.1 - 3.4e-07 30.6 3.2 0.44 11.0 0.0 4.8 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.6 KFP00931.1 - 3.2e-06 26.9 3.9 0.068 13.0 0.4 3.8 4 0 0 4 4 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP00931.1 - 5.4e-06 25.7 3.4 0.47 10.0 0.0 3.8 3 0 0 3 3 3 2 EF hand Spc7 PF08317.11 KFP00931.1 - 0.00043 19.3 22.8 0.00043 19.3 22.8 2.9 2 1 1 3 3 2 1 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 KFP00931.1 - 0.0025 17.8 19.0 0.0025 17.8 19.0 4.6 3 1 3 6 6 4 2 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.6 KFP00931.1 - 0.019 13.6 25.8 0.24 10.0 4.0 2.2 1 1 1 2 2 2 0 AAA domain ESSS PF10183.9 KFP00931.1 - 0.088 13.0 0.5 0.25 11.6 0.5 1.7 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) UIM PF02809.20 KFP00931.1 - 0.21 11.6 6.1 0.49 10.4 3.5 3.0 2 0 0 2 2 2 0 Ubiquitin interaction motif Atg14 PF10186.9 KFP00931.1 - 0.66 9.0 32.1 2.3 7.2 9.5 3.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 KFP00931.1 - 0.86 10.1 54.5 0.31 11.6 13.7 3.7 2 1 1 3 3 3 0 Apg6 coiled-coil region RasGAP_C PF03836.15 KFP00931.1 - 1.8 8.7 26.0 2.1 8.5 4.1 3.3 1 1 2 3 3 3 0 RasGAP C-terminus Leu_zip PF15294.6 KFP00931.1 - 2.4 7.6 31.3 0.4 10.2 26.8 2.0 1 1 1 2 2 2 0 Leucine zipper DUF3584 PF12128.8 KFP00931.1 - 3.2 5.1 39.0 0.028 12.0 29.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.10 KFP00931.1 - 4.1 7.6 24.7 1.6 8.9 10.1 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family HOOK PF05622.12 KFP00931.1 - 4.2 5.4 38.4 0.35 9.0 23.8 2.2 1 1 1 2 2 2 0 HOOK protein DUF1664 PF07889.12 KFP00931.1 - 4.9 7.2 21.0 0.27 11.3 6.3 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 KFP00931.1 - 5 7.1 19.9 7.5 6.6 1.5 2.9 1 1 1 2 2 2 0 Laminin Domain II TMPIT PF07851.13 KFP00931.1 - 6.4 5.9 26.8 0.75 9.0 14.6 2.2 1 1 1 2 2 2 0 TMPIT-like protein Tweety PF04906.13 KFP00931.1 - 7.3 5.1 13.0 2.1 7.0 0.5 2.2 1 1 0 2 2 2 0 Tweety UPF0242 PF06785.11 KFP00931.1 - 7.8 6.6 44.9 0.69 10.0 4.1 3.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Peptidase_M16_M PF16187.5 KFP00932.1 - 4.3e-88 295.2 0.6 7.2e-88 294.5 0.6 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KFP00932.1 - 2.9e-40 137.7 0.1 1.6e-39 135.3 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFP00932.1 - 2.6e-35 122.1 1.6 8.9e-21 74.7 0.0 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain SDA1 PF05285.12 KFP00932.1 - 0.0079 15.7 16.4 0.012 15.0 16.4 1.2 1 0 0 1 1 1 1 SDA1 Mpp10 PF04006.12 KFP00932.1 - 0.36 9.2 13.9 0.7 8.3 13.9 1.4 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 KFP00932.1 - 0.69 8.0 22.2 1.1 7.4 22.2 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 KFP00932.1 - 6.3 5.3 19.1 11 4.5 19.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ras PF00071.22 KFP00933.1 - 6.6e-43 146.1 1.3 5.6e-38 130.1 0.8 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KFP00933.1 - 1e-27 96.8 0.4 1.5e-27 96.2 0.4 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP00933.1 - 7.5e-10 38.5 0.4 1.1e-09 38.0 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFP00933.1 - 1.7e-05 24.3 0.1 4.1e-05 23.1 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFP00933.1 - 0.001 19.2 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFP00933.1 - 0.0025 17.2 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Septin PF00735.18 KFP00933.1 - 0.089 12.1 0.0 0.38 10.0 0.0 1.8 2 0 0 2 2 2 0 Septin G-alpha PF00503.20 KFP00933.1 - 0.56 9.3 3.5 5 6.2 0.0 2.9 2 1 1 3 3 3 0 G-protein alpha subunit Thioredoxin_7 PF13899.6 KFP00934.1 - 5.8e-18 64.9 0.0 9.6e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 KFP00934.1 - 2.7e-06 27.3 0.0 4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KFP00934.1 - 0.00043 20.7 0.0 0.00068 20.1 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredox_DsbH PF03190.15 KFP00934.1 - 0.0058 16.6 0.1 0.0071 16.3 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_9 PF14595.6 KFP00934.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.6 KFP00934.1 - 0.016 15.5 0.2 0.069 13.5 0.0 2.0 2 1 0 2 2 2 0 Thioredoxin-like AhpC-TSA PF00578.21 KFP00934.1 - 0.026 14.4 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Glutaredoxin PF00462.24 KFP00934.1 - 0.09 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin NAC PF01849.18 KFP00935.1 - 4.7e-25 87.3 0.1 8.2e-25 86.6 0.1 1.4 1 0 0 1 1 1 1 NAC domain RVT_1 PF00078.27 KFP00936.1 - 1.5e-11 44.3 0.0 3.8e-11 42.9 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFP00936.1 - 0.033 14.2 0.0 0.1 12.6 0.0 1.9 3 0 0 3 3 3 0 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFP00937.1 - 1.4e-15 57.5 0.0 1.8e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 KFP00937.1 - 8.8e-11 41.5 0.2 1.4e-10 40.9 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase thumb domain RRM_1 PF00076.22 KFP00940.1 - 0.0014 18.4 0.4 1.9 8.4 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_2 PF00891.18 KFP00941.1 - 4.9e-84 280.8 0.0 6.5e-84 280.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KFP00941.1 - 3.5e-34 116.6 0.1 7e-34 115.7 0.1 1.5 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_25 PF13649.6 KFP00941.1 - 6.6e-08 33.2 0.0 1.3e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP00941.1 - 1.6e-05 25.5 0.0 3.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP00941.1 - 0.00012 22.8 0.0 0.00023 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP00941.1 - 0.00013 21.9 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP00941.1 - 0.00072 19.4 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.11 KFP00941.1 - 0.0016 18.4 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain MTS PF05175.14 KFP00941.1 - 0.0065 16.0 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain zf_C2H2_13 PF18508.1 KFP00941.1 - 0.2 11.3 0.0 0.99 9.0 0.0 2.0 2 0 0 2 2 2 0 Zinc finger domain adh_short PF00106.25 KFP00942.1 - 5.5e-20 71.7 0.0 3.5e-19 69.0 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP00942.1 - 9.4e-11 41.7 0.0 5.4e-10 39.2 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 KFP00942.1 - 0.06 12.7 0.1 0.083 12.3 0.1 1.4 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase zf-BED PF02892.15 KFP00943.1 - 4.8e-16 58.5 1.0 1.3e-15 57.1 1.0 1.8 1 0 0 1 1 1 1 BED zinc finger Dimer_Tnp_hAT PF05699.14 KFP00943.1 - 2.1e-14 53.1 0.1 6.3e-14 51.5 0.1 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KFP00943.1 - 8.2e-05 22.9 1.6 0.00032 21.0 0.7 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) CD99L2 PF12301.8 KFP00944.1 - 2.9e-15 57.0 5.6 3.1e-15 56.9 5.6 1.0 1 0 0 1 1 1 1 CD99 antigen like protein 2 Glycophorin_A PF01102.18 KFP00944.1 - 0.025 14.8 0.1 0.025 14.8 0.1 1.0 1 0 0 1 1 1 0 Glycophorin A ENOD93 PF03386.14 KFP00944.1 - 0.035 14.0 0.6 0.039 13.8 0.6 1.1 1 0 0 1 1 1 0 Early nodulin 93 ENOD93 protein CD99L2 PF12301.8 KFP00945.1 - 2.6e-14 53.8 1.2 3.4e-13 50.3 1.2 2.2 1 1 0 1 1 1 1 CD99 antigen like protein 2 DUF5323 PF17257.2 KFP00945.1 - 0.57 10.1 2.5 0.96 9.4 0.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5323) Glyco_transf_8 PF01501.20 KFP00946.1 - 1.8e-20 73.6 0.0 4.1e-18 65.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 KFP00946.1 - 0.0031 17.5 0.0 0.0045 17.0 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.8 KFP00946.1 - 0.0032 16.8 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative TLV_coat PF00429.19 KFP00947.1 - 0.0091 14.7 0.2 0.0096 14.7 0.2 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) AKNA PF12443.8 KFP00947.1 - 0.02 15.5 0.2 0.022 15.4 0.2 1.1 1 0 0 1 1 1 0 AT-hook-containing transcription factor SPT_ssu-like PF11779.8 KFP00948.1 - 4.6e-15 55.0 9.1 5.8e-15 54.7 9.1 1.1 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like DUF2499 PF10693.9 KFP00948.1 - 0.031 14.6 0.5 0.042 14.1 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2499) NMD3 PF04981.13 KFP00949.1 - 2.9e-81 272.5 7.0 4.2e-81 272.0 7.0 1.2 1 0 0 1 1 1 1 NMD3 family DUF1221 PF06760.11 KFP00949.1 - 0.011 15.3 0.7 0.03 13.8 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) TMEM37 PF15108.6 KFP00949.1 - 0.039 13.8 0.1 0.072 13.0 0.1 1.5 1 0 0 1 1 1 0 Voltage-dependent calcium channel gamma-like subunit protein family DUF1289 PF06945.13 KFP00949.1 - 0.12 12.2 2.6 6.1 6.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) DZR PF12773.7 KFP00949.1 - 2.2 8.4 11.9 41 4.3 11.9 2.8 1 1 0 1 1 1 0 Double zinc ribbon Amelogenin PF02948.15 KFP00950.1 - 0.97 10.1 15.8 3.5 8.2 15.8 1.8 1 1 0 1 1 1 0 Amelogenin C1q PF00386.21 KFP00951.1 - 1.4e-33 115.8 0.0 1.7e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFP00951.1 - 3.6e-14 52.3 47.9 1.5e-10 40.7 23.8 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) TPR_2 PF07719.17 KFP00952.1 - 5.3e-16 57.4 21.3 0.00065 19.6 0.0 9.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFP00952.1 - 3.6e-13 48.7 14.4 0.0011 18.6 0.0 7.7 7 1 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFP00952.1 - 1.6e-12 46.6 13.7 0.00088 19.3 0.0 8.5 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFP00952.1 - 2.8e-11 43.2 6.9 0.11 13.4 0.1 7.8 4 2 4 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFP00952.1 - 6.7e-11 42.2 0.2 5e-07 29.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFP00952.1 - 1.4e-08 34.3 0.0 0.00026 20.6 0.2 4.4 3 1 1 4 4 4 1 TPR repeat TPR_19 PF14559.6 KFP00952.1 - 4.2e-08 33.6 2.4 0.00091 19.7 0.0 6.0 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFP00952.1 - 4e-07 30.6 2.0 0.00024 21.7 0.2 4.4 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFP00952.1 - 7.5e-07 29.1 7.3 8.8e-05 22.6 0.0 5.0 7 0 0 7 7 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFP00952.1 - 9.6e-06 25.8 17.6 0.18 12.1 0.9 7.2 5 3 3 8 8 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP00952.1 - 1.8e-05 24.8 15.2 0.007 16.6 0.3 5.6 3 1 3 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KFP00952.1 - 0.00048 20.0 7.0 28 5.0 0.0 6.4 5 1 0 6 6 6 0 Tetratricopeptide repeat BTAD PF03704.17 KFP00952.1 - 0.0034 17.8 3.7 0.05 14.0 0.9 3.6 2 2 0 2 2 2 1 Bacterial transcriptional activator domain TPR_6 PF13174.6 KFP00952.1 - 0.0042 17.6 9.2 0.79 10.5 0.0 6.8 9 0 0 9 9 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFP00952.1 - 0.0094 15.8 12.3 10 6.2 0.2 7.8 7 1 1 8 8 8 0 Tetratricopeptide repeat ChAPs PF09295.10 KFP00952.1 - 0.022 13.8 0.0 0.94 8.4 0.0 2.3 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) DSHCT PF08148.12 KFP00952.1 - 0.051 13.2 0.1 0.16 11.7 0.1 1.8 1 0 0 1 1 1 0 DSHCT (NUC185) domain RPN7 PF10602.9 KFP00952.1 - 0.071 12.8 4.4 1.2 8.8 0.0 4.2 5 1 0 5 5 4 0 26S proteasome subunit RPN7 TPR_15 PF13429.6 KFP00952.1 - 0.09 12.0 5.5 0.69 9.1 0.6 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat SNAP PF14938.6 KFP00952.1 - 0.24 10.8 7.3 4.1 6.7 0.2 3.9 2 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP Fis1_TPR_C PF14853.6 KFP00952.1 - 1.3 9.1 6.0 7.5 6.7 0.1 4.6 4 1 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat BIRC6 PF12356.8 KFP00953.1 - 3.6e-59 199.1 3.3 3.6e-59 199.1 3.3 2.4 3 0 0 3 3 3 1 Baculoviral IAP repeat-containing protein 6 UQ_con PF00179.26 KFP00953.1 - 1.4e-30 105.8 0.0 2.9e-30 104.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BIR PF00653.21 KFP00953.1 - 1.1e-20 74.0 3.0 2.8e-20 72.7 3.0 1.7 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain UEV PF05743.13 KFP00953.1 - 0.00011 22.0 0.0 0.0003 20.6 0.0 1.7 1 0 0 1 1 1 1 UEV domain IL13 PF03487.13 KFP00953.1 - 0.56 10.0 2.7 1.4 8.7 0.3 3.0 2 0 0 2 2 2 0 Interleukin-13 Yip1 PF04893.17 KFP00954.1 - 3.7e-10 39.8 21.2 8.9e-10 38.5 20.9 1.8 1 1 0 1 1 1 1 Yip1 domain UPF0139 PF03669.13 KFP00954.1 - 0.067 13.1 0.3 0.13 12.1 0.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) BORG_CEP PF14957.6 KFP00955.1 - 9.8e-33 114.0 3.1 1.5e-32 113.4 3.1 1.3 1 0 0 1 1 1 1 Cdc42 effector PBD PF00786.28 KFP00955.1 - 1e-08 35.4 0.1 1e-08 35.4 0.1 2.1 3 0 0 3 3 3 1 P21-Rho-binding domain TPR_1 PF00515.28 KFP00956.1 - 1.4e-05 24.7 3.1 0.0038 17.0 0.7 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFP00956.1 - 0.00018 21.3 2.0 0.051 13.7 0.2 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat BUD22 PF09073.10 KFP00956.1 - 0.0024 17.3 4.3 0.0029 17.0 4.3 1.1 1 0 0 1 1 1 1 BUD22 TPR_8 PF13181.6 KFP00956.1 - 0.0036 17.4 5.0 0.29 11.5 0.5 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP00956.1 - 0.008 16.7 0.0 0.041 14.4 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFP00956.1 - 0.031 14.7 0.8 6 7.5 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat CCDC106 PF15794.5 KFP00956.1 - 0.036 13.8 2.4 0.064 13.0 2.4 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SKA1 PF07160.12 KFP00956.1 - 0.037 13.9 2.3 0.06 13.2 2.3 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 TPR_6 PF13174.6 KFP00956.1 - 0.055 14.1 0.8 1.4 9.7 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Sec16_C PF12931.7 KFP00956.1 - 0.081 12.6 0.2 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 TPR_11 PF13414.6 KFP00956.1 - 0.12 12.1 0.0 0.76 9.5 0.0 2.2 2 0 0 2 2 2 0 TPR repeat TPR_7 PF13176.6 KFP00956.1 - 0.15 12.1 0.1 0.77 9.9 0.0 2.3 2 0 0 2 2 1 0 Tetratricopeptide repeat RVT_1 PF00078.27 KFP00957.1 - 0.00015 21.4 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MuF_C PF18819.1 KFP00957.1 - 0.15 12.0 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Phage MuF-C-terminal domain DUF1725 PF08333.11 KFP00957.1 - 0.24 11.1 0.6 0.38 10.5 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) HAD_2 PF13419.6 KFP00958.1 - 7.6e-24 84.8 0.0 1e-23 84.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFP00958.1 - 1.8e-13 51.3 0.0 2.2e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFP00958.1 - 9.9e-12 44.8 0.0 2.1e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like DUF4187 PF13821.6 KFP00959.1 - 4.9e-20 71.0 1.1 4.9e-20 71.0 1.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KFP00959.1 - 1.4e-14 53.7 1.1 2.6e-14 52.8 1.1 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFP00959.1 - 2.2e-06 27.7 0.5 2.2e-06 27.7 0.5 2.6 2 0 0 2 2 2 1 G-patch domain DUF1840 PF08895.11 KFP00959.1 - 9.8 6.6 11.5 2.1 8.7 1.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) HEAT_2 PF13646.6 KFP00960.1 - 4.4e-09 36.6 11.4 0.087 13.2 0.1 7.4 5 1 1 6 6 6 4 HEAT repeats HEAT PF02985.22 KFP00960.1 - 1.1e-07 31.5 37.2 0.34 11.3 1.4 11.7 11 0 0 11 11 11 4 HEAT repeat IFRD PF05004.13 KFP00960.1 - 0.00083 18.6 9.4 0.44 9.6 1.2 5.8 6 1 0 6 6 6 2 Interferon-related developmental regulator (IFRD) MMS22L_C PF14911.6 KFP00960.1 - 0.026 13.6 1.6 1.2 8.2 0.1 2.6 2 0 0 2 2 2 0 S-phase genomic integrity recombination mediator, C-terminal DnaB_bind PF10410.9 KFP00960.1 - 0.13 12.4 0.0 0.59 10.4 0.0 2.2 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase HisKA_3 PF07730.13 KFP00960.1 - 0.3 11.6 2.5 1.7 9.3 0.1 3.4 3 0 0 3 3 3 0 Histidine kinase WD40 PF00400.32 KFP00961.1 - 3.7e-35 119.4 11.6 3e-08 34.2 0.1 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat Striatin PF08232.12 KFP00961.1 - 5.7e-27 95.2 3.2 5.7e-27 95.2 3.2 2.7 2 2 0 2 2 2 1 Striatin family ANAPC4_WD40 PF12894.7 KFP00961.1 - 9.5e-09 35.4 0.1 0.023 15.0 0.0 5.5 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KFP00961.1 - 0.0046 15.8 0.0 5.5 5.6 0.0 3.3 1 1 0 3 3 3 2 Nup133 N terminal like Nup160 PF11715.8 KFP00961.1 - 0.02 13.6 0.0 3.4 6.2 0.0 2.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 VWA PF00092.28 KFP00962.1 - 7.1e-82 273.9 0.4 4.4e-43 147.6 0.5 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 KFP00962.1 - 3.4e-34 117.7 0.0 1.1e-15 58.1 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain LCCL PF03815.19 KFP00962.1 - 1.1e-24 86.3 0.1 3.7e-24 84.6 0.1 1.9 1 0 0 1 1 1 1 LCCL domain VWA_3 PF13768.6 KFP00962.1 - 1.2e-07 31.8 0.0 0.012 15.6 0.0 2.6 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_CoxE PF05762.14 KFP00962.1 - 0.00057 19.3 0.0 0.054 12.9 0.0 2.6 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein DUF1194 PF06707.11 KFP00962.1 - 0.0016 17.7 0.1 1.2 8.3 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1194) Rxt3 PF08642.10 KFP00962.1 - 0.011 16.4 0.1 0.039 14.7 0.1 2.0 1 1 0 1 1 1 0 Histone deacetylation protein Rxt3 Mucin PF01456.17 KFP00962.1 - 0.015 15.2 15.7 0.026 14.5 15.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein ETS_PEA3_N PF04621.13 KFP00962.1 - 0.48 10.2 3.9 0.97 9.2 3.9 1.4 1 0 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain 7tm_1 PF00001.21 KFP00963.1 - 3.2e-28 98.8 12.2 3.7e-28 98.6 12.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RVT_1 PF00078.27 KFP00964.1 - 0.07 12.6 0.0 0.18 11.3 0.0 1.8 3 0 0 3 3 3 0 Reverse transcriptase (RNA-dependent DNA polymerase) FEZ PF07763.13 KFP00965.1 - 4.3e-88 295.1 14.8 5.4e-88 294.8 14.8 1.1 1 0 0 1 1 1 1 FEZ-like protein DUF5102 PF17104.5 KFP00965.1 - 0.038 14.1 9.2 0.12 12.3 8.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5102) Gluconate_2-dh3 PF13618.6 KFP00965.1 - 0.039 14.2 0.2 0.078 13.2 0.2 1.5 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 EURL PF06937.11 KFP00965.1 - 0.13 11.6 8.4 0.044 13.2 5.6 1.6 1 1 1 2 2 2 0 EURL protein Ribosomal_L12_N PF16320.5 KFP00965.1 - 0.46 10.2 6.5 0.37 10.5 1.0 2.5 2 0 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain CdiI_2 PF18593.1 KFP00965.1 - 0.9 10.2 6.4 7.2 7.3 0.3 3.0 1 1 0 2 2 2 0 CdiI immunity protein V_ATPase_I PF01496.19 KFP00965.1 - 1.5 6.6 6.8 1.8 6.4 6.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.12 KFP00965.1 - 3.5 8.2 9.1 11 6.5 0.8 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein VWC PF00093.18 KFP00966.1 - 1.6e-38 130.8 127.3 4.2e-11 43.0 14.5 16.2 10 2 6 16 16 16 7 von Willebrand factor type C domain Antistasin PF02822.14 KFP00966.1 - 7.5e-16 58.5 61.5 9.5e-07 29.3 10.2 15.5 16 2 1 17 17 17 4 Antistasin family IGFBP PF00219.18 KFP00966.1 - 1.6e-07 31.9 19.4 1.6e-07 31.9 19.4 16.2 8 4 8 16 16 16 1 Insulin-like growth factor binding protein TILa PF12714.7 KFP00966.1 - 0.0015 18.5 26.8 0.0019 18.1 5.9 13.4 11 2 3 14 14 14 5 TILa domain Amnionless PF14828.6 KFP00966.1 - 0.0032 16.4 13.3 0.0032 16.4 13.3 9.3 11 0 0 11 11 11 6 Amnionless CBF PF03914.17 KFP00967.1 - 4.9e-57 192.7 0.5 4.9e-57 192.7 0.5 3.0 2 1 0 2 2 2 1 CBF/Mak21 family Cnd1 PF12717.7 KFP00967.1 - 2.8e-05 24.2 0.5 9.4e-05 22.5 0.5 1.8 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Methyltransf_28 PF02636.17 KFP00968.1 - 1.4e-75 254.3 0.0 2.4e-75 253.5 0.0 1.4 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pkinase PF00069.25 KFP00969.1 - 1.5e-70 237.6 0.0 2.5e-70 236.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP00969.1 - 6.6e-33 114.1 0.0 1e-32 113.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KFP00969.1 - 3.7e-28 97.2 19.2 2.9e-14 52.7 3.0 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 KFP00969.1 - 1.4e-09 38.4 0.3 3.8e-07 30.6 0.1 3.3 3 0 0 3 3 3 1 PH domain Kinase-like PF14531.6 KFP00969.1 - 1.6e-07 30.9 0.0 3.4e-06 26.6 0.0 2.6 2 1 0 3 3 3 1 Kinase-like C1_2 PF03107.16 KFP00969.1 - 1.3e-05 25.4 15.0 0.0095 16.2 1.6 2.6 2 0 0 2 2 2 2 C1 domain Kdo PF06293.14 KFP00969.1 - 1.9e-05 24.1 0.0 3.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_9 PF13901.6 KFP00969.1 - 0.061 13.3 12.8 1.1 9.2 0.4 2.5 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon APH PF01636.23 KFP00969.1 - 0.13 12.2 0.0 1.3 8.9 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KFP00969.1 - 0.13 11.8 0.2 0.26 10.9 0.2 1.4 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 KFP00969.1 - 0.13 11.2 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PHD PF00628.29 KFP00969.1 - 0.14 12.1 16.7 1.5 8.7 3.2 2.6 2 0 0 2 2 2 0 PHD-finger FYVE_2 PF02318.16 KFP00969.1 - 0.8 9.9 11.0 3.4 7.9 5.7 2.6 2 0 0 2 2 2 0 FYVE-type zinc finger Peptidase_M28 PF04389.17 KFP00970.1 - 4.8e-47 160.2 0.0 6.2e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Get5_C PF18514.1 KFP00970.1 - 0.045 13.5 0.3 0.12 12.2 0.3 1.7 1 0 0 1 1 1 0 Get5 C-terminal domain Cation_efflux PF01545.21 KFP00971.1 - 1.9e-32 112.6 14.8 3e-32 112.0 14.8 1.3 1 0 0 1 1 1 1 Cation efflux family AAA PF00004.29 KFP00972.1 - 1e-39 136.0 0.0 2.8e-39 134.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFP00972.1 - 8e-09 35.2 0.0 2e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KFP00972.1 - 4e-06 26.7 0.0 1.1e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 KFP00972.1 - 1.1e-05 25.3 0.0 2.8e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 KFP00972.1 - 4.7e-05 23.7 0.4 0.019 15.2 0.1 3.4 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFP00972.1 - 0.00014 21.8 0.2 0.0024 17.9 0.2 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KFP00972.1 - 0.00031 20.1 0.1 0.00095 18.5 0.0 1.7 1 1 1 2 2 2 1 TIP49 P-loop domain TniB PF05621.11 KFP00972.1 - 0.00071 19.0 1.5 0.4 10.1 0.0 3.3 3 1 1 4 4 4 2 Bacterial TniB protein AAA_2 PF07724.14 KFP00972.1 - 0.0012 19.0 0.0 0.0043 17.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 KFP00972.1 - 0.0023 17.3 0.5 0.008 15.6 0.5 1.9 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KFP00972.1 - 0.0037 17.7 1.9 0.16 12.4 1.4 3.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KFP00972.1 - 0.0057 16.7 0.0 0.045 13.8 0.0 2.4 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KFP00972.1 - 0.0093 15.7 0.2 0.02 14.7 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 KFP00972.1 - 0.014 15.2 0.0 0.033 13.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KFP00972.1 - 0.016 14.4 0.0 0.035 13.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 KFP00972.1 - 0.032 14.1 0.0 0.085 12.7 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein MIT PF04212.18 KFP00972.1 - 0.045 13.8 0.1 0.12 12.5 0.1 1.8 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain AAA_18 PF13238.6 KFP00972.1 - 0.082 13.4 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFP00972.1 - 0.087 13.0 0.0 0.28 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KFP00972.1 - 0.13 11.8 0.1 0.93 9.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain Dpy-30 PF05186.13 KFP00973.1 - 3.6e-21 74.6 0.4 3.6e-21 74.6 0.4 1.5 2 0 0 2 2 2 1 Dpy-30 motif RIIa PF02197.17 KFP00973.1 - 0.0019 17.8 0.0 0.0035 17.0 0.0 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Bmp PF02608.14 KFP00973.1 - 0.13 11.2 0.1 0.15 11.0 0.1 1.1 1 0 0 1 1 1 0 ABC transporter substrate-binding protein PnrA-like Memo PF01875.17 KFP00974.1 - 9.3e-75 251.3 0.0 1.1e-74 251.0 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Glycolytic PF00274.19 KFP00974.1 - 0.068 11.9 0.1 0.098 11.4 0.1 1.1 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I Steroid_dh PF02544.16 KFP00975.1 - 1.4e-59 200.4 3.7 1.6e-59 200.2 3.7 1.1 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KFP00975.1 - 2.8e-06 27.0 0.1 3.4e-06 26.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KFP00975.1 - 0.013 15.8 1.7 0.037 14.4 1.7 1.7 1 1 0 1 1 1 0 Phospholipid methyltransferase ELYS-bb PF16687.5 KFP00976.1 - 1.1e-294 977.4 0.2 1.6e-294 976.9 0.2 1.2 1 0 0 1 1 1 1 beta-propeller of ELYS nucleoporin ELYS PF13934.6 KFP00976.1 - 1.4e-54 185.4 0.4 2.5e-54 184.6 0.4 1.4 1 0 0 1 1 1 1 Nuclear pore complex assembly Sacchrp_dh_C PF16653.5 KFP00977.1 - 1.1e-11 45.3 0.0 2.9e-11 44.0 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KFP00977.1 - 4.3e-06 27.0 0.0 6.6e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Consortin_C PF15281.6 KFP00978.1 - 6.3e-55 184.0 1.4 2.5e-54 182.1 0.1 2.5 2 0 0 2 2 2 1 Consortin C-terminus TPR_7 PF13176.6 KFP00978.1 - 0.02 14.9 0.2 0.27 11.3 0.3 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFP00978.1 - 0.17 12.1 0.2 0.57 10.5 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat RrnaAD PF00398.20 KFP00979.1 - 1.4e-13 50.5 0.0 2e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase APOBEC_N PF08210.11 KFP00979.1 - 0.053 13.4 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 APOBEC-like N-terminal domain SET PF00856.28 KFP00980.1 - 4.1e-13 50.1 0.1 4.8e-12 46.6 0.0 2.0 2 0 0 2 2 2 1 SET domain TPR_12 PF13424.6 KFP00980.1 - 1.2e-05 25.5 0.2 4.6e-05 23.6 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat HrpE PF06188.12 KFP00980.1 - 0.042 13.7 0.2 0.042 13.7 0.2 1.6 2 0 0 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E Kinesin PF00225.23 KFP00981.1 - 2.5e-61 207.5 0.0 4e-61 206.8 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFP00981.1 - 9e-16 58.2 0.0 1.8e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding AAA_33 PF13671.6 KFP00982.1 - 7.5e-28 97.5 0.3 1.5e-27 96.5 0.1 1.5 2 0 0 2 2 2 1 AAA domain SPRY PF00622.28 KFP00982.1 - 2.1e-14 53.7 0.2 2.1e-14 53.7 0.2 1.8 2 0 0 2 2 2 1 SPRY domain SRP54 PF00448.22 KFP00982.1 - 0.022 14.4 0.2 0.038 13.6 0.2 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 KFP00982.1 - 0.11 11.7 0.2 0.28 10.4 0.2 1.6 1 1 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 KFP00982.1 - 0.12 12.9 0.0 0.35 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF3767 PF12597.8 KFP00983.1 - 4e-14 52.3 0.1 4.6e-14 52.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Peptidase_C97 PF05903.14 KFP00984.1 - 2.7e-39 134.4 0.0 3.5e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain YxiJ PF14176.6 KFP00984.1 - 0.1 13.1 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 YxiJ-like protein LRAT PF04970.13 KFP00984.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Adenylsucc_synt PF00709.21 KFP00985.1 - 3.4e-160 533.5 0.0 3.9e-160 533.4 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Spore_YpjB PF09577.10 KFP00985.1 - 0.066 13.0 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) FadA PF09403.10 KFP00985.1 - 0.13 12.7 0.1 0.27 11.7 0.1 1.5 1 0 0 1 1 1 0 Adhesion protein FadA BTB PF00651.31 KFP00986.1 - 2.2e-27 95.5 1.3 3.8e-27 94.7 1.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.6 KFP00986.1 - 1.8e-15 56.3 29.8 0.00031 21.3 3.1 5.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP00986.1 - 7.7e-15 54.6 26.8 1.1e-07 31.9 1.9 5.7 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFP00986.1 - 1.3e-13 50.6 34.7 0.00079 19.8 2.4 5.0 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFP00986.1 - 3.6e-05 23.9 15.6 0.0037 17.5 0.0 4.7 4 1 1 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP00986.1 - 0.0011 18.9 22.3 0.35 10.9 2.0 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 KFP00986.1 - 0.0027 18.0 0.1 0.0027 18.0 0.1 5.3 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFP00986.1 - 0.012 15.3 19.9 0.28 11.0 0.4 4.6 5 0 0 5 5 5 0 zinc-finger C2H2-type Zn-C2H2_12 PF18112.1 KFP00986.1 - 0.018 15.5 2.0 0.018 15.5 2.0 3.2 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain GAGA PF09237.11 KFP00986.1 - 0.022 14.5 6.3 0.54 10.1 0.2 3.5 2 1 1 3 3 3 0 GAGA factor CpXC PF14353.6 KFP00986.1 - 0.027 14.5 6.2 0.37 10.9 0.5 2.7 2 0 0 2 2 2 0 CpXC protein zf_C2H2_10 PF18414.1 KFP00986.1 - 0.1 12.2 1.4 0.34 10.5 1.4 1.9 1 0 0 1 1 1 0 C2H2 type zinc-finger zf_UBZ PF18439.1 KFP00986.1 - 0.16 11.6 7.0 3.6 7.2 0.2 3.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFP00986.1 - 0.3 11.2 7.3 0.36 11.0 0.9 3.3 2 1 1 3 3 3 0 Zinc ribbon domain zf-LYAR PF08790.11 KFP00986.1 - 0.32 11.0 9.6 0.63 10.0 0.4 4.2 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger PknG_rubred PF16919.5 KFP00986.1 - 2.1 8.5 5.6 0.46 10.7 0.6 2.5 2 1 2 4 4 4 0 Protein kinase G rubredoxin domain zinc_ribbon_15 PF17032.5 KFP00986.1 - 3 8.7 9.8 1.4e+02 3.3 6.4 3.5 2 1 1 3 3 3 0 zinc-ribbon family FYVE PF01363.21 KFP00986.1 - 5.5 7.2 20.0 12 6.1 5.1 4.5 3 1 2 5 5 5 0 FYVE zinc finger XPA_N PF01286.18 KFP00986.1 - 8.1 6.6 9.4 26 4.9 0.1 4.1 4 0 0 4 4 4 0 XPA protein N-terminal Pkinase PF00069.25 KFP00987.1 - 2.9e-77 259.6 0.1 6.4e-77 258.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP00987.1 - 2.3e-36 125.4 0.0 3.2e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KFP00987.1 - 1.1e-10 42.0 0.3 3.1e-10 40.5 0.1 1.9 2 0 0 2 2 2 1 PH domain Pkinase_C PF00433.24 KFP00987.1 - 1.3e-09 38.6 2.7 2.7e-09 37.6 2.7 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFP00987.1 - 1.3e-08 34.5 0.0 3.5e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KFP00987.1 - 0.0091 15.6 0.4 0.97 9.0 0.1 2.3 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFP00987.1 - 0.19 11.6 0.4 0.37 10.7 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family CEP170_C PF15308.6 KFP00988.1 - 7.4e-262 870.8 61.0 7.4e-262 870.8 61.0 3.6 4 0 0 4 4 4 1 CEP170 C-terminus FHA PF00498.26 KFP00988.1 - 3.8e-15 56.0 0.0 1.4e-14 54.2 0.0 2.1 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFP00988.1 - 3.4e-09 36.9 0.0 1.1e-08 35.2 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Trns_repr_metal PF02583.17 KFP00988.1 - 0.13 12.6 2.3 1.2 9.6 0.0 2.7 2 0 0 2 2 2 0 Metal-sensitive transcriptional repressor DUF4254 PF14063.6 KFP00988.1 - 1.3 8.9 6.7 0.085 12.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4254) PLDc_3 PF13918.6 KFP00989.1 - 1.4e-82 275.6 0.9 2.6e-82 274.8 0.9 1.4 1 0 0 1 1 1 1 PLD-like domain PLDc_2 PF13091.6 KFP00989.1 - 3.1e-12 46.5 0.1 1.4e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KFP00989.1 - 1.5e-08 34.5 1.2 0.00014 21.9 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif FAM83 PF07894.12 KFP00989.1 - 0.07 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 FAM83 A-H Atg8 PF02991.16 KFP00990.1 - 3.4e-39 133.2 0.3 3.8e-39 133.0 0.3 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KFP00990.1 - 5.7e-06 26.6 0.1 7.2e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 XPG_I PF00867.18 KFP00991.1 - 2.4e-24 85.5 0.1 7.6e-24 83.9 0.1 2.0 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KFP00991.1 - 1.6e-22 79.8 0.0 3.6e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 KFP00991.1 - 0.00035 20.1 0.9 0.00077 19.0 0.0 1.9 2 0 0 2 2 2 1 XPG domain containing WD40 PF00400.32 KFP00992.1 - 2.4e-08 34.5 0.0 0.013 16.4 0.0 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP00992.1 - 0.0011 19.3 0.1 0.053 13.8 0.1 2.6 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Ig_Tie2_1 PF10430.9 KFP00992.1 - 0.045 14.2 0.0 0.088 13.2 0.0 1.5 1 0 0 1 1 1 0 Tie-2 Ig-like domain 1 Nucleoporin_N PF08801.11 KFP00992.1 - 0.15 10.8 0.0 6.4 5.4 0.0 2.0 1 1 1 2 2 2 0 Nup133 N terminal like WD40 PF00400.32 KFP00993.1 - 0.25 12.3 1.4 20 6.3 0.1 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat 7tm_1 PF00001.21 KFP00994.1 - 2.6e-22 79.4 12.8 3.1e-22 79.2 12.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Herpes_UL49_5 PF05702.11 KFP00994.1 - 0.047 13.8 0.9 3.3 7.9 0.1 2.5 2 0 0 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein Imm39 PF15568.6 KFP00994.1 - 0.092 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 39 IRK PF01007.20 KFP00994.1 - 0.53 10.1 10.1 2.6 7.9 1.8 2.4 2 1 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain Pex24p PF06398.11 KFP00994.1 - 0.78 8.7 6.7 5.3 5.9 2.9 2.2 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin DHHC PF01529.20 KFP00994.1 - 1.5 8.9 8.0 0.22 11.6 4.1 1.6 2 0 0 2 2 2 0 DHHC palmitoyltransferase Mannosyl_trans PF05007.13 KFP00995.1 - 3.6e-98 328.6 21.7 4.4e-98 328.3 21.7 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KFP00995.1 - 2.1e-09 36.9 15.8 2.1e-09 36.9 15.8 1.8 1 1 1 2 2 2 1 GPI transamidase subunit PIG-U TAT_signal PF10518.9 KFP00995.1 - 8.7 6.4 7.2 62 3.7 0.0 3.0 3 0 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence RGS_DHEX PF18148.1 KFP00996.1 - 3e-50 168.4 1.6 3e-50 168.4 1.6 2.2 2 0 0 2 2 2 1 Regulator of G-protein signalling DHEX domain RGS PF00615.19 KFP00996.1 - 1.7e-35 121.8 1.6 5.8e-35 120.1 0.0 2.5 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.21 KFP00996.1 - 1.1e-18 67.1 0.0 7.2e-18 64.4 0.0 2.3 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.22 KFP00996.1 - 4.9e-15 55.3 0.1 2e-14 53.3 0.1 2.0 1 0 0 1 1 1 1 GGL domain RGS-like PF09128.11 KFP00996.1 - 0.084 12.6 0.0 0.084 12.6 0.0 2.0 3 0 0 3 3 3 0 Regulator of G protein signalling-like domain DAN PF03045.15 KFP00997.1 - 5.2e-41 139.2 10.8 7.1e-41 138.8 10.8 1.1 1 0 0 1 1 1 1 DAN domain Sfi1_C PF10638.9 KFP00997.1 - 0.091 13.5 0.9 0.15 12.9 0.2 1.7 2 0 0 2 2 2 0 Spindle body associated protein C-terminus NTP_transf_9 PF04248.12 KFP00997.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF427) FH2 PF02181.23 KFP00998.1 - 0.027 13.6 0.3 0.027 13.6 0.3 1.5 2 0 0 2 2 2 0 Formin Homology 2 Domain FH2 PF02181.23 KFP00999.1 - 1.6e-78 264.4 8.5 2.6e-78 263.7 8.5 1.3 1 1 0 1 1 1 1 Formin Homology 2 Domain Drf_FH1 PF06346.12 KFP00999.1 - 0.00014 21.6 96.2 0.075 12.8 96.2 2.2 1 1 0 1 1 1 1 Formin Homology Region 1 IFN-gamma PF00714.17 KFP00999.1 - 0.22 11.4 4.4 0.15 11.9 0.2 2.6 2 1 0 2 2 2 0 Interferon gamma 7tm_1 PF00001.21 KFP01000.1 - 2.6e-78 263.0 1.1 3.6e-78 262.5 1.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP01000.1 - 2.5e-08 33.6 5.7 2.5e-08 33.6 5.7 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP01000.1 - 3.6e-07 30.1 11.2 3.6e-07 30.1 11.2 2.6 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP01000.1 - 1.4e-05 25.0 3.0 1.4e-05 25.0 3.0 2.4 3 0 0 3 3 3 2 Olfactory receptor Phosphodiest PF01663.22 KFP01001.1 - 1.5e-83 281.4 0.0 1.9e-83 281.0 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Endonuclease_NS PF01223.23 KFP01001.1 - 5.4e-10 39.5 0.1 9.2e-10 38.7 0.1 1.3 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Sulfatase PF00884.23 KFP01001.1 - 4.7e-05 22.9 0.0 0.004 16.6 0.0 2.3 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KFP01001.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Cys_knot PF00007.22 KFP01002.1 - 2.4e-16 59.9 9.9 2.4e-16 59.9 9.9 2.9 3 1 0 3 3 3 1 Cystine-knot domain VWC PF00093.18 KFP01002.1 - 2.3e-10 40.6 9.4 2.3e-10 40.6 9.4 3.8 2 1 0 2 2 2 1 von Willebrand factor type C domain TSP_1 PF00090.19 KFP01002.1 - 6.2e-06 26.3 6.2 6.2e-06 26.3 6.2 2.9 2 0 0 2 2 2 1 Thrombospondin type 1 domain Cu2_monooxygen PF01082.20 KFP01003.1 - 4.4e-49 166.1 0.9 8.8e-49 165.1 0.9 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 KFP01003.1 - 2.7e-42 144.0 0.0 4.9e-42 143.1 0.0 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DOMON PF03351.17 KFP01003.1 - 5.4e-12 46.0 0.2 9.3e-12 45.3 0.2 1.4 1 0 0 1 1 1 1 DOMON domain DUF1987 PF09345.10 KFP01003.1 - 0.098 12.3 0.1 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1987) Syntaxin_2 PF14523.6 KFP01004.1 - 4.1e-30 104.1 15.5 4.3e-29 100.9 8.3 2.1 2 0 0 2 2 2 2 Syntaxin-like protein Syntaxin PF00804.25 KFP01004.1 - 6.6e-12 45.5 11.3 3.2e-11 43.3 11.3 2.0 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 KFP01004.1 - 5.4e-10 39.1 0.7 1.5e-09 37.7 0.7 1.8 1 0 0 1 1 1 1 SNARE domain DASH_Dad4 PF08650.10 KFP01004.1 - 0.0025 17.7 3.8 0.075 13.0 0.1 2.9 2 1 1 3 3 3 1 DASH complex subunit Dad4 Cep57_CLD_2 PF14197.6 KFP01004.1 - 0.04 14.0 4.7 0.84 9.8 0.2 2.8 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF948 PF06103.11 KFP01004.1 - 0.091 13.0 5.9 3.5 7.9 0.2 3.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF5329 PF17263.2 KFP01004.1 - 0.11 12.7 1.0 1.6 9.0 0.1 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5329) T3SS_needle_E PF08988.10 KFP01004.1 - 0.23 11.6 0.1 0.23 11.6 0.1 3.8 4 1 1 5 5 5 0 Type III secretion system, cytoplasmic E component of needle 4HB_MCP_1 PF12729.7 KFP01004.1 - 0.57 9.7 9.8 0.18 11.3 2.4 2.5 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction IL15 PF02372.15 KFP01004.1 - 0.66 10.0 4.7 0.18 11.8 0.5 2.1 2 2 0 2 2 2 0 Interleukin 15 FUSC PF04632.12 KFP01004.1 - 0.81 8.2 3.9 0.65 8.5 2.9 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family Spectrin PF00435.21 KFP01004.1 - 2 8.9 15.2 3.3 8.2 5.2 3.2 2 2 0 2 2 2 0 Spectrin repeat OmpH PF03938.14 KFP01004.1 - 4.7 7.6 18.7 0.4 11.0 8.5 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) CCDC-167 PF15188.6 KFP01004.1 - 5.9 7.3 12.6 0.21 11.9 1.3 3.4 2 2 2 4 4 4 0 Coiled-coil domain-containing protein 167 DUF2203 PF09969.9 KFP01004.1 - 6.6 7.5 9.6 3.4 8.4 0.8 2.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) 7tm_1 PF00001.21 KFP01005.1 - 5.1e-52 176.8 17.4 6.8e-52 176.4 17.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP01005.1 - 7.4e-06 25.9 13.3 7.4e-06 25.9 13.3 1.6 2 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP01005.1 - 0.00095 18.9 20.1 0.00095 18.9 20.1 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 KFP01006.1 - 1.4e-60 204.9 17.6 1.9e-60 204.4 17.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP01006.1 - 5.8e-05 22.6 27.8 8.2e-05 22.1 27.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP01006.1 - 0.026 14.2 29.5 0.012 15.2 26.4 2.0 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Herpes_US9 PF06072.11 KFP01006.1 - 0.26 11.2 4.3 0.31 10.9 0.1 3.1 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 CN_hydrolase PF00795.22 KFP01007.1 - 9.1e-23 80.9 0.0 1.3e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Sec10 PF07393.11 KFP01007.1 - 0.25 9.7 0.0 0.32 9.4 0.0 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 CN_hydrolase PF00795.22 KFP01008.1 - 1.5e-07 31.0 0.0 0.0017 17.8 0.0 2.3 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase MFS_1 PF07690.16 KFP01009.1 - 2.2e-38 132.1 68.4 2.2e-23 82.7 34.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFP01009.1 - 0.00041 19.3 27.7 0.013 14.3 5.4 3.6 1 1 1 2 2 2 2 MFS_1 like family LacY_symp PF01306.19 KFP01009.1 - 0.031 13.0 19.8 0.051 12.3 0.9 2.5 1 1 1 2 2 2 0 LacY proton/sugar symporter Ribosomal_L7Ae PF01248.26 KFP01010.1 - 4.4e-30 103.3 1.9 5.4e-30 103.0 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase PF00702.26 KFP01011.1 - 8.1e-07 29.5 0.0 1.1e-06 29.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HLH PF00010.26 KFP01012.1 - 9.5e-16 57.5 0.2 1.5e-15 56.9 0.2 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TBP PF00352.21 KFP01013.1 - 2.9e-45 152.1 0.4 6.2e-23 80.6 0.1 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KFP01013.1 - 0.0018 18.3 0.0 0.012 15.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3378) Sugar_tr PF00083.24 KFP01014.1 - 5.7e-101 338.6 27.2 2.4e-76 257.4 14.9 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFP01014.1 - 1.1e-29 103.5 35.7 9.6e-26 90.5 23.4 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_3 PF16080.5 KFP01014.1 - 0.4 10.5 0.0 0.4 10.5 0.0 3.4 3 0 0 3 3 3 0 Bacteriophage holin family HP1 RVT_1 PF00078.27 KFP01015.1 - 0.064 12.8 0.0 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Aldedh PF00171.22 KFP01016.1 - 1.1e-169 564.8 0.0 1.3e-169 564.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KFP01016.1 - 0.13 11.7 0.0 1 8.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) GTP_EFTU PF00009.27 KFP01017.1 - 7.8e-48 162.6 0.5 1.4e-47 161.8 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFP01017.1 - 4e-30 104.4 1.7 5.6e-30 103.9 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain HBS1_N PF08938.10 KFP01017.1 - 1.2e-20 73.6 3.4 2.6e-20 72.5 3.4 1.6 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D2 PF03144.25 KFP01017.1 - 3.4e-07 30.5 0.0 1.1e-06 29.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFP01017.1 - 1.7e-06 28.1 2.1 6.9e-05 22.9 0.1 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KFP01017.1 - 0.0059 16.9 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 KFP01017.1 - 0.051 13.0 0.4 4.5 6.6 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF1296 PF06972.11 KFP01017.1 - 0.16 12.1 0.9 0.54 10.4 0.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Arf PF00025.21 KFP01017.1 - 0.17 11.3 4.8 4.2 6.8 0.8 3.2 3 0 0 3 3 3 0 ADP-ribosylation factor family Cmyb_C PF09316.10 KFP01018.1 - 2.3e-75 251.8 3.0 4.1e-75 251.0 3.0 1.4 1 0 0 1 1 1 1 C-myb, C-terminal Myb_DNA-binding PF00249.31 KFP01018.1 - 7.5e-52 173.3 20.2 6.4e-18 64.7 1.9 3.9 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFP01018.1 - 2.7e-40 136.4 16.8 3e-17 62.6 1.9 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain LMSTEN PF07988.12 KFP01018.1 - 9.7e-27 92.2 0.6 2e-26 91.2 0.6 1.6 1 0 0 1 1 1 1 LMSTEN motif Myb_DNA-bind_7 PF15963.5 KFP01018.1 - 6e-09 35.7 8.1 0.00035 20.4 0.1 3.9 2 1 2 4 4 4 2 Myb DNA-binding like SLIDE PF09111.10 KFP01018.1 - 1.5e-06 28.2 0.5 1.3 9.1 0.0 4.1 2 1 2 4 4 4 3 SLIDE SANT_DAMP1_like PF16282.5 KFP01018.1 - 0.0001 22.4 3.4 0.37 11.0 0.0 3.5 1 1 2 3 3 3 2 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 KFP01018.1 - 0.08 13.0 7.9 1.9 8.7 0.3 3.6 1 1 2 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Spore_III_AB PF09548.10 KFP01018.1 - 1.1 9.3 4.6 0.83 9.7 0.1 2.9 2 1 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) PDEase_I PF00233.19 KFP01019.1 - 8.2e-76 254.8 0.7 1.1e-75 254.4 0.7 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase THRAP3_BCLAF1 PF15440.6 KFP01020.1 - 1.5e-188 629.0 104.2 1.5e-188 629.0 104.2 2.6 2 1 1 3 3 3 1 THRAP3/BCLAF1 family GRP PF07172.11 KFP01020.1 - 1.4 9.6 16.7 0.035 14.8 5.2 3.7 2 1 0 2 2 2 0 Glycine rich protein family Ipi1_N PF12333.8 KFP01021.1 - 0.084 13.5 0.1 0.14 12.8 0.1 1.5 1 1 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation MAP7 PF05672.11 KFP01022.1 - 5.9e-43 146.4 83.2 5.9e-43 146.4 83.2 3.5 4 0 0 4 4 4 2 MAP7 (E-MAP-115) family WD40 PF00400.32 KFP01023.1 - 7.5e-24 83.6 12.7 7.3e-06 26.6 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.11 KFP01023.1 - 0.00011 22.2 0.1 0.0011 18.9 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KFP01023.1 - 0.023 15.0 0.7 1.6 9.1 0.1 3.3 2 2 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP01023.1 - 0.74 8.4 3.7 47 2.4 0.0 3.7 4 1 1 5 5 5 0 Nucleoporin Nup120/160 DUF4199 PF13858.6 KFP01024.1 - 0.0026 18.2 0.9 0.023 15.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4199) EamA PF00892.20 KFP01024.1 - 0.012 15.8 11.1 0.014 15.5 11.1 1.1 1 0 0 1 1 1 0 EamA-like transporter family DUF2070 PF09843.9 KFP01024.1 - 0.19 10.0 5.4 0.24 9.6 5.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) VIT1 PF01988.19 KFP01024.1 - 0.35 10.7 4.0 0.11 12.4 0.3 1.8 1 1 1 2 2 2 0 VIT family 7TMR-DISM_7TM PF07695.11 KFP01024.1 - 5 7.0 10.6 13 5.6 10.5 1.7 1 1 0 1 1 1 0 7TM diverse intracellular signalling Tissue_fac PF01108.17 KFP01025.1 - 3.5e-26 91.1 0.1 1.1e-25 89.6 0.1 1.9 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.10 KFP01025.1 - 1.3e-19 70.5 0.6 8.5e-19 67.8 0.1 2.4 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.17 KFP01026.1 - 6.9e-33 112.7 0.2 1e-32 112.2 0.2 1.3 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.10 KFP01026.1 - 9.9e-17 61.2 0.1 3.2e-16 59.5 0.0 1.7 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.17 KFP01027.1 - 1.3e-20 73.2 0.2 1.4e-20 73.1 0.2 1.0 1 0 0 1 1 1 1 Tissue factor HLH PF00010.26 KFP01028.1 - 2.3e-12 46.7 0.3 4.3e-12 45.8 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain zf-A20 PF01754.16 KFP01029.1 - 2.3e-31 107.4 77.8 1.5e-08 34.4 2.9 7.9 8 0 0 8 8 8 6 A20-like zinc finger OTU PF02338.19 KFP01029.1 - 1.7e-29 102.9 0.0 5e-29 101.4 0.0 1.9 1 0 0 1 1 1 1 OTU-like cysteine protease PMP22_Claudin PF00822.20 KFP01030.1 - 1.6e-07 31.3 9.6 2e-07 31.0 9.6 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 KFP01030.1 - 0.0013 19.0 7.7 0.0031 17.8 7.7 1.7 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PalH PF08733.10 KFP01030.1 - 0.051 12.6 3.2 0.068 12.2 3.2 1.1 1 0 0 1 1 1 0 PalH/RIM21 PTR2 PF00854.21 KFP01030.1 - 0.16 10.8 9.7 1.3 7.7 2.4 2.3 1 1 1 2 2 2 0 POT family Pox_A14 PF05767.12 KFP01030.1 - 3.9 7.7 8.2 0.63 10.2 4.1 1.7 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 PMP22_Claudin PF00822.20 KFP01031.1 - 8.4e-11 42.0 3.6 1.2e-10 41.5 3.6 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 KFP01031.1 - 0.00084 19.6 5.8 0.0026 18.0 5.9 1.8 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PalH PF08733.10 KFP01031.1 - 0.73 8.8 3.9 0.96 8.4 3.9 1.1 1 0 0 1 1 1 0 PalH/RIM21 Pox_A14 PF05767.12 KFP01031.1 - 1.5 9.0 8.8 2.3 8.4 5.4 2.3 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 DCB PF16213.5 KFP01032.1 - 1.3e-08 34.7 5.7 1.3e-08 34.7 5.7 3.2 2 1 1 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 KFP01032.1 - 1.3e-06 28.2 7.8 6e-05 22.8 1.4 5.0 4 1 0 4 4 4 1 Domain of unknown function (DUF1981) Sec7_N PF12783.7 KFP01032.1 - 0.00065 19.6 0.2 0.00065 19.6 0.2 3.4 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal SWIRM-assoc_1 PF16495.5 KFP01032.1 - 0.49 10.4 6.6 0.1 12.6 2.1 2.3 2 0 0 2 2 2 0 SWIRM-associated region 1 MMR_HSR1_C PF08438.10 KFP01032.1 - 0.73 10.4 4.2 25 5.5 0.1 3.8 4 0 0 4 4 4 0 GTPase of unknown function C-terminal RVT_1 PF00078.27 KFP01033.1 - 0.0052 16.3 0.0 0.0084 15.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4061 PF13270.6 KFP01034.1 - 2.7e-29 101.3 2.0 3.7e-29 100.9 2.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) Costars PF14705.6 KFP01035.1 - 6.1e-31 106.4 0.5 6.7e-31 106.3 0.5 1.0 1 0 0 1 1 1 1 Costars Headcase PF16002.5 KFP01036.1 - 4.7e-83 277.5 4.0 4.7e-83 277.5 4.0 1.7 2 0 0 2 2 2 1 Headcase protein HECA PF15353.6 KFP01036.1 - 4.5e-40 136.0 8.8 1.2e-39 134.6 8.8 1.8 1 0 0 1 1 1 1 Headcase protein family homologue HypA PF01155.19 KFP01036.1 - 5.5 7.1 7.6 9.6 6.3 4.3 2.6 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 KFP01036.1 - 7.2 6.5 10.9 5.8 6.8 0.4 3.4 3 0 0 3 3 3 0 zinc-ribbon domain CITED PF04487.12 KFP01037.1 - 9.8e-115 382.4 8.5 1.1e-114 382.2 8.5 1.0 1 0 0 1 1 1 1 CITED 7tm_1 PF00001.21 KFP01039.1 - 5.8e-53 179.9 15.0 7.1e-53 179.6 15.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFP01039.1 - 1.8e-10 40.6 9.4 2.4e-10 40.2 9.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.9 KFP01039.1 - 5.3e-08 32.5 14.2 7.5e-08 32.1 14.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 KFP01039.1 - 0.66 9.2 15.1 1.5 8.0 15.1 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Connexin PF00029.19 KFP01040.1 - 1.9e-30 106.4 12.1 7.5e-16 58.6 0.1 2.0 1 1 1 2 2 2 2 Connexin DUF846 PF05832.12 KFP01040.1 - 0.004 17.2 10.5 0.16 12.0 7.9 2.5 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF846) Vta1 PF04652.16 KFP01041.1 - 2.6e-40 137.7 2.8 5.9e-40 136.6 1.6 1.9 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 KFP01041.1 - 1.8e-18 66.0 0.6 1.8e-18 66.0 0.6 1.6 2 0 0 2 2 2 1 Vta1 C-terminal domain DAG_kinase_N PF14513.6 KFP01041.1 - 0.13 12.4 0.5 0.36 11.0 0.0 1.9 2 1 0 2 2 2 0 Diacylglycerol kinase N-terminus 7tm_2 PF00002.24 KFP01042.1 - 2e-48 164.8 16.2 2e-48 164.8 16.2 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) CUB PF00431.20 KFP01042.1 - 2.5e-24 85.7 0.0 6.1e-24 84.5 0.0 1.7 1 0 0 1 1 1 1 CUB domain GPS PF01825.21 KFP01042.1 - 1.2e-17 64.1 3.2 3.8e-17 62.5 3.2 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Pentaxin PF00354.17 KFP01042.1 - 3.9e-09 36.5 0.4 1.9e-08 34.3 0.2 2.1 2 0 0 2 2 2 1 Pentaxin family Frizzled PF01534.17 KFP01042.1 - 0.00064 18.8 19.5 0.4 9.7 19.5 2.6 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region Laminin_G_3 PF13385.6 KFP01042.1 - 0.0032 17.6 0.1 0.0078 16.4 0.1 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily CUB_2 PF02408.20 KFP01042.1 - 0.032 14.0 0.1 0.14 12.0 0.1 2.1 1 0 0 1 1 1 0 CUB-like domain FIVAR PF07554.13 KFP01042.1 - 0.082 13.7 0.4 0.082 13.7 0.4 2.6 2 0 0 2 2 2 0 FIVAR domain zf-C2H2 PF00096.26 KFP01043.1 - 2.7e-18 65.3 27.8 0.00011 22.4 1.4 5.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFP01043.1 - 1.2e-10 41.4 23.7 0.0021 18.3 1.5 4.8 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KFP01043.1 - 1.9e-10 40.7 38.0 1.8e-06 28.1 1.0 5.3 6 0 0 6 6 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP01043.1 - 1.2e-09 38.1 23.8 0.07 14.0 0.4 5.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 KFP01043.1 - 7.1e-05 23.1 25.4 0.0093 16.3 2.8 5.3 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFP01043.1 - 0.00073 19.2 21.7 0.15 11.8 0.8 4.7 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 KFP01043.1 - 0.079 13.6 7.3 8.2 7.1 0.4 4.2 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats NOA36 PF06524.12 KFP01043.1 - 0.11 11.8 24.9 0.12 11.7 14.5 2.5 2 0 0 2 2 2 0 NOA36 protein RNA_pol_Rpb8 PF03870.15 KFP01043.1 - 0.21 11.8 1.3 8.1 6.6 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase Rpb8 zf-C2H2_2 PF12756.7 KFP01043.1 - 0.64 10.4 18.7 0.21 11.9 4.2 4.0 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) RRN3 PF05327.11 KFP01043.1 - 2.9 6.3 7.6 5.4 5.4 7.6 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 zf-Di19 PF05605.12 KFP01043.1 - 8 6.8 14.8 4.2 7.8 4.0 2.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Far-17a_AIG1 PF04750.14 KFP01044.1 - 1.5e-76 256.2 12.4 1.7e-76 256.1 12.4 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein dCMP_cyt_deam_1 PF00383.23 KFP01046.1 - 9.1e-18 64.0 0.7 1.2e-17 63.6 0.7 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFP01046.1 - 3.1e-16 59.4 0.0 3.9e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 KFP01046.1 - 0.00015 21.8 0.0 0.00024 21.2 0.0 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 KFP01046.1 - 0.00018 21.6 0.0 0.00026 21.1 0.0 1.2 1 0 0 1 1 1 1 APOBEC2 NAD1 PF18778.1 KFP01046.1 - 0.00033 20.8 0.0 0.00045 20.4 0.0 1.1 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 Bd3614-deam PF14439.6 KFP01046.1 - 0.001 19.2 3.8 0.02 15.0 3.8 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC3 PF18771.1 KFP01046.1 - 0.0082 16.3 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 APOBEC3 APOBEC_N PF08210.11 KFP01046.1 - 0.009 15.9 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC4_like PF18774.1 KFP01046.1 - 0.017 15.1 0.1 0.026 14.5 0.1 1.3 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase NAD2 PF18782.1 KFP01046.1 - 0.04 14.0 0.0 0.056 13.6 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 Peroxin-3 PF04882.12 KFP01047.1 - 4.4e-65 220.5 7.5 1.8e-48 165.7 1.6 3.0 1 1 1 2 2 2 2 Peroxin-3 DUF3631 PF12307.8 KFP01047.1 - 0.087 13.0 0.2 0.32 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3631) Alpha_L_fucos PF01120.17 KFP01048.1 - 2.6e-126 421.8 4.0 3e-126 421.6 4.0 1.0 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 KFP01048.1 - 3e-28 98.2 0.5 7.2e-28 97.0 0.5 1.7 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain RPEL PF02755.15 KFP01049.1 - 8.3e-28 95.2 21.9 1.3e-07 31.0 2.5 4.5 4 0 0 4 4 4 4 RPEL repeat Tail_tube PF10618.9 KFP01049.1 - 0.12 12.3 0.3 0.23 11.3 0.3 1.5 1 0 0 1 1 1 0 Phage tail tube protein PBP1_TM PF14812.6 KFP01049.1 - 1.4 9.4 12.8 0.17 12.3 4.7 3.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SieB PF14163.6 KFP01049.1 - 2.7 7.5 7.1 1.6 8.2 2.8 2.8 3 1 0 3 3 3 0 Super-infection exclusion protein B LTV PF04180.14 KFP01050.1 - 1.2e-86 291.9 14.5 1.1e-85 288.7 14.5 2.2 1 1 0 1 1 1 1 Low temperature viability protein UPF0767 PF15990.5 KFP01050.1 - 1.8 8.7 7.2 1.6 8.9 4.8 2.1 2 0 0 2 2 2 0 UPF0767 family zf-C2H2_4 PF13894.6 KFP01051.1 - 8e-20 69.8 54.4 0.0031 18.2 5.1 7.7 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP01051.1 - 1.9e-17 62.6 62.5 0.0012 19.2 7.8 7.6 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP01051.1 - 1.2e-12 47.7 62.9 0.0046 17.3 4.4 8.7 8 1 0 8 8 8 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFP01051.1 - 0.00027 21.1 31.3 0.61 10.4 2.6 6.3 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KFP01051.1 - 0.0027 18.0 26.0 0.03 14.6 10.0 4.0 1 1 2 3 3 3 2 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 KFP01051.1 - 0.008 16.5 33.4 3 8.2 12.7 4.7 1 1 3 4 4 4 3 C2H2 type zinc-finger (2 copies) Acyltransf_C PF16076.5 KFP01051.1 - 0.044 13.9 2.2 5.2 7.2 0.4 2.6 2 1 0 2 2 2 0 Acyltransferase C-terminus zf-C2H2_3rep PF18868.1 KFP01051.1 - 0.072 13.8 20.4 0.12 13.0 1.9 4.2 2 1 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 KFP01051.1 - 0.14 11.9 0.1 0.14 11.9 0.1 5.5 6 0 0 6 6 6 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFP01051.1 - 0.27 11.3 0.2 0.27 11.3 0.2 7.1 7 0 0 7 7 7 0 C2H2-type zinc finger zf-Di19 PF05605.12 KFP01051.1 - 2.6 8.4 33.9 0.53 10.6 5.4 5.3 1 1 4 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding zf-LITAF-like PF10601.9 KFP01051.1 - 8.3 6.8 16.7 0.36 11.1 3.8 3.8 2 1 2 4 4 4 0 LITAF-like zinc ribbon domain SET PF00856.28 KFP01052.1 - 0.0037 17.7 0.0 0.043 14.2 0.0 2.1 1 1 0 1 1 1 1 SET domain zf_UBZ PF18439.1 KFP01052.1 - 0.26 10.9 1.5 6.6 6.4 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_4 PF13894.6 KFP01052.1 - 4.7 8.3 7.2 6.7 7.8 0.4 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Radial_spoke_3 PF06098.11 KFP01053.1 - 3.8e-128 426.7 15.2 4.3e-128 426.6 15.2 1.0 1 0 0 1 1 1 1 Radial spoke protein 3 DUF2866 PF11065.8 KFP01053.1 - 0.23 11.5 3.3 1.5 8.9 1.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2866) DUF4574 PF15141.6 KFP01053.1 - 0.46 10.4 4.9 1.2 9.1 4.9 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 RhoGAP PF00620.27 KFP01054.1 - 1.3e-40 138.7 0.6 2.4e-40 137.8 0.6 1.5 1 0 0 1 1 1 1 RhoGAP domain AMPKBI PF04739.15 KFP01054.1 - 0.024 14.9 1.1 6.4 7.1 0.2 3.0 2 0 0 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interaction domain COMM_domain PF07258.14 KFP01055.1 - 1.7e-06 28.0 0.0 3.9e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 COMM domain Neil1-DNA_bind PF09292.10 KFP01056.1 - 1.2e-25 89.2 0.7 2.5e-25 88.1 0.3 1.8 2 0 0 2 2 2 1 Endonuclease VIII-like 1, DNA bind H2TH PF06831.14 KFP01056.1 - 1.5e-08 34.5 0.0 2.1e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Glyco_hydro_38N PF01074.22 KFP01057.1 - 1.2e-85 287.4 0.1 2.1e-85 286.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KFP01057.1 - 8e-51 173.1 0.0 1.5e-50 172.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KFP01057.1 - 8.8e-27 93.1 0.1 2.9e-26 91.4 0.0 1.9 2 0 0 2 2 2 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KFP01057.1 - 3.7e-09 36.6 0.0 9.5e-09 35.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain MHCassoc_trimer PF08831.10 KFP01057.1 - 0.44 10.6 3.3 0.88 9.6 2.1 2.0 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain Sin3a_C PF16879.5 KFP01058.1 - 6.2e-101 337.9 8.7 6.2e-101 337.9 8.7 2.3 2 1 0 2 2 2 1 C-terminal domain of Sin3a protein PAH PF02671.21 KFP01058.1 - 5.4e-50 167.3 5.0 6.9e-19 67.7 0.0 4.1 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KFP01058.1 - 5.7e-42 141.8 0.2 1.6e-41 140.3 0.2 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor Y_phosphatase PF00102.27 KFP01059.1 - 2.2e-80 269.6 0.0 3.1e-80 269.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CRAL_TRIO PF00650.20 KFP01059.1 - 6.2e-31 107.3 0.1 1.6e-30 105.9 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFP01059.1 - 5.6e-11 42.8 0.0 1.1e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DSPc PF00782.20 KFP01059.1 - 0.0053 16.6 0.7 0.016 15.1 0.1 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP01059.1 - 0.0056 16.7 0.0 0.009 16.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family CRAL_TRIO_N PF03765.15 KFP01059.1 - 0.016 15.4 0.7 0.34 11.1 0.0 2.9 3 0 0 3 3 3 0 CRAL/TRIO, N-terminal domain PTPlike_phytase PF14566.6 KFP01059.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Snurportin1 PF11538.8 KFP01060.1 - 0.48 10.7 2.0 1.1 9.5 2.0 1.6 1 0 0 1 1 1 0 Snurportin1 BAR_3_WASP_bdg PF10456.9 KFP01061.1 - 3.6e-108 360.5 3.9 4.7e-108 360.1 3.9 1.1 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.24 KFP01061.1 - 1.6e-20 73.2 3.1 3.2e-20 72.2 1.3 2.2 2 0 0 2 2 2 1 PX domain SH3_9 PF14604.6 KFP01061.1 - 5.4e-12 45.4 0.0 1.3e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP01061.1 - 3.7e-10 39.3 0.0 9e-10 38.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP01061.1 - 1e-08 34.7 0.0 3e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Vps5 PF09325.10 KFP01061.1 - 0.00034 20.2 2.1 0.037 13.6 0.8 3.0 1 1 1 2 2 2 2 Vps5 C terminal like TetR_C_22 PF17928.1 KFP01061.1 - 0.16 12.3 0.0 1.6 9.1 0.0 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain CAP_N PF01213.19 KFP01061.1 - 0.21 11.0 0.4 1.3 8.4 0.1 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Cadherin_3 PF16184.5 KFP01062.1 - 2.9e-201 655.1 13.4 6.7e-29 100.1 0.0 14.2 14 0 0 14 14 14 14 Cadherin-like Cadherin_4 PF17803.1 KFP01062.1 - 0.0022 18.6 3.8 2 9.1 0.0 4.9 4 1 0 4 4 4 1 Bacterial cadherin-like domain LRR_8 PF13855.6 KFP01063.1 - 1.4e-55 184.9 55.6 2.2e-12 46.6 1.7 6.4 1 1 6 7 7 7 7 Leucine rich repeat LRR_5 PF13306.6 KFP01063.1 - 1.9e-28 99.0 0.2 3.9e-12 46.2 0.0 3.1 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFP01063.1 - 4.9e-20 71.3 34.8 0.00019 21.7 2.1 7.3 5 1 2 7 7 7 7 Leucine Rich repeats (2 copies) I-set PF07679.16 KFP01063.1 - 1.5e-14 53.8 0.0 2.7e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP01063.1 - 5.1e-12 46.2 0.0 1.1e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP01063.1 - 3e-08 33.7 0.0 5.5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP01063.1 - 1.1e-07 32.0 0.0 2.5e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.6 KFP01063.1 - 1.4e-06 28.0 14.2 0.00043 19.8 2.8 3.6 2 2 1 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 KFP01063.1 - 4.1e-06 26.6 37.1 11 7.1 0.0 11.8 12 1 0 12 12 12 2 Leucine Rich Repeat LRRNT PF01462.18 KFP01063.1 - 0.052 13.2 9.1 0.037 13.7 3.2 3.2 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain V-set PF07686.17 KFP01063.1 - 0.19 11.9 0.0 0.87 9.8 0.0 2.1 1 1 0 1 1 1 0 Immunoglobulin V-set domain LRR_6 PF13516.6 KFP01063.1 - 0.41 10.8 36.9 6.4 7.1 0.1 10.0 11 0 0 11 11 11 0 Leucine Rich repeat HMG_box PF00505.19 KFP01064.1 - 3.1e-19 69.2 1.4 9.9e-19 67.5 1.4 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP01064.1 - 1.6e-12 47.8 0.7 1.6e-12 47.8 0.7 2.7 2 1 1 3 3 3 1 HMG-box domain DUF4763 PF15960.5 KFP01064.1 - 0.0028 17.0 3.7 0.0028 17.0 3.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4763) Trans_reg_C PF00486.28 KFP01064.1 - 0.0032 17.5 0.3 0.61 10.2 0.0 3.1 2 1 1 3 3 3 1 Transcriptional regulatory protein, C terminal COG5 PF10392.9 KFP01064.1 - 0.049 13.8 4.0 0.067 13.4 2.3 2.0 2 0 0 2 2 2 0 Golgi transport complex subunit 5 CENP-C_mid PF15620.6 KFP01064.1 - 0.59 10.1 17.1 2.7 7.9 1.5 2.3 2 0 0 2 2 2 0 Centromere assembly component CENP-C middle DNMT3B-binding region Pkinase PF00069.25 KFP01065.1 - 2e-12 47.0 0.0 4.2e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP01065.1 - 6.4e-06 25.6 0.0 1.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFP01065.1 - 0.15 11.9 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tetraspanin PF00335.20 KFP01066.1 - 3.4e-43 148.0 13.3 4.4e-43 147.6 13.3 1.1 1 0 0 1 1 1 1 Tetraspanin family Hum_adeno_E3A PF05393.11 KFP01066.1 - 0.049 13.6 4.0 0.2 11.6 0.3 2.4 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein COX2_TM PF02790.15 KFP01066.1 - 0.16 12.1 6.3 10 6.4 0.2 3.2 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain 7tm_4 PF13853.6 KFP01068.1 - 1.7e-28 100.2 15.9 2.3e-26 93.2 10.7 2.0 1 1 1 2 2 2 2 Olfactory receptor 7tm_1 PF00001.21 KFP01068.1 - 7.2e-19 68.1 13.0 7.2e-19 68.1 13.0 2.1 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Yae1_N PF09811.9 KFP01069.1 - 3.7e-13 48.9 55.3 1.8e+04 -24.7 55.3 5.8 1 1 0 1 1 1 0 Essential protein Yae1, N terminal DUF4205 PF13898.6 KFP01070.1 - 4.4e-55 187.0 0.1 2.2e-51 174.9 0.0 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4205) UPF0560 PF10577.9 KFP01071.1 - 0 1310.7 6.0 0 1310.5 6.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0560 FAM176 PF14851.6 KFP01071.1 - 0.038 13.6 4.5 9.4 5.9 3.3 2.7 2 0 0 2 2 2 0 FAM176 family Orthoreo_P10 PF07204.11 KFP01071.1 - 0.13 12.2 0.1 0.31 11.0 0.1 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Adeno_E3_CR2 PF02439.15 KFP01071.1 - 0.44 10.3 1.9 0.8 9.5 1.9 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 NMT_C PF02799.15 KFP01072.1 - 3.7e-81 271.7 0.2 6.1e-81 270.9 0.2 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KFP01072.1 - 3.5e-76 254.5 0.0 6.2e-76 253.7 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 KFP01072.1 - 0.00025 21.3 0.0 0.00045 20.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KFP01072.1 - 0.042 13.9 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain TFIIF_alpha PF05793.12 KFP01072.1 - 6.6 5.2 13.5 8.4 4.9 13.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ribosomal_L7Ae PF01248.26 KFP01073.1 - 2e-08 33.8 0.0 4.1e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KFP01073.1 - 2.5e-05 24.4 0.0 0.0097 16.0 0.0 2.2 2 0 0 2 2 2 2 RNase P subunit Pop3 ACBP PF00887.19 KFP01074.1 - 4.2e-30 103.8 0.5 4.6e-30 103.7 0.5 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein JmjN PF02375.17 KFP01074.1 - 0.12 12.4 0.8 1.4 8.9 0.1 2.2 2 0 0 2 2 2 0 jmjN domain Carn_acyltransf PF00755.20 KFP01075.1 - 1.3e-172 575.5 0.0 1.5e-172 575.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Vasohibin PF14822.6 KFP01075.1 - 0.19 10.9 0.8 5.7 6.1 0.1 2.6 3 0 0 3 3 3 0 Vasohibin RUN PF02759.19 KFP01076.1 - 4.7e-25 88.1 0.1 1.1e-24 86.9 0.0 1.7 2 0 0 2 2 2 1 RUN domain DUF4477 PF14780.6 KFP01076.1 - 0.015 14.9 0.5 0.071 12.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4477) Drf_FH3 PF06367.16 KFP01076.1 - 0.034 13.8 4.1 0.097 12.3 4.1 1.7 1 1 0 1 1 1 0 Diaphanous FH3 Domain IpaB_EvcA PF03278.13 KFP01076.1 - 0.13 12.0 0.8 0.41 10.3 0.2 2.0 2 0 0 2 2 2 0 IpaB/EvcA family Mito_carr PF00153.27 KFP01077.1 - 3.2e-59 196.9 0.9 3.9e-20 71.6 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 KFP01077.1 - 0.087 13.1 0.0 22 5.3 0.0 2.3 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Reprolysin PF01421.19 KFP01078.1 - 7.9e-61 205.4 0.0 7.9e-61 205.4 0.0 2.0 3 0 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.12 KFP01078.1 - 1.5e-17 64.1 8.9 1.5e-17 64.1 8.9 4.0 3 2 0 3 3 3 1 ADAM cysteine-rich Pep_M12B_propep PF01562.19 KFP01078.1 - 1.2e-15 58.0 2.1 1.2e-15 58.0 2.1 1.9 2 0 0 2 2 2 1 Reprolysin family propeptide Disintegrin PF00200.23 KFP01078.1 - 7.4e-15 55.5 30.0 7.4e-15 55.5 30.0 4.0 4 1 0 4 4 4 1 Disintegrin Reprolysin_3 PF13582.6 KFP01078.1 - 4.2e-08 33.8 0.0 8.5e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFP01078.1 - 2.3e-06 27.9 0.0 7.5e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12 EGF_2 PF07974.13 KFP01078.1 - 0.0012 19.2 10.8 0.0012 19.2 10.8 6.4 4 2 0 4 4 4 1 EGF-like domain EF-hand_1 PF00036.32 KFP01079.1 - 2.1e-15 55.0 0.8 0.00036 19.9 0.0 5.3 5 1 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 KFP01079.1 - 3.2e-13 49.3 0.9 2.2e-10 40.2 0.0 3.5 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP01079.1 - 2.5e-12 45.6 0.1 0.0012 18.6 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KFP01079.1 - 8.7e-11 40.8 0.2 0.012 15.0 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KFP01079.1 - 2.6e-10 40.6 0.1 0.00058 20.3 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain pair DUF3854 PF12965.7 KFP01079.1 - 0.048 13.6 0.0 0.071 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) DUF2835 PF11197.8 KFP01079.1 - 0.068 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2835) Ferric_reduct PF01794.19 KFP01080.1 - 2e-12 47.3 11.4 2.6e-12 46.9 3.9 2.5 1 1 1 2 2 2 2 Ferric reductase like transmembrane component F420_oxidored PF03807.17 KFP01080.1 - 1.2e-10 41.9 0.0 2e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KFP01080.1 - 0.00036 19.9 0.0 0.00063 19.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KFP01080.1 - 0.00051 19.7 0.0 0.00094 18.8 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 KFP01080.1 - 0.0012 19.0 0.0 0.0019 18.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Rossmann-like PF10727.9 KFP01080.1 - 0.0094 15.8 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Rossmann-like domain RVT_1 PF00078.27 KFP01081.1 - 0.051 13.1 0.0 0.36 10.3 0.0 2.1 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2_jaz PF12171.8 KFP01082.1 - 7.2e-07 29.3 10.5 4.6e-06 26.8 10.5 2.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Ferric_reduct PF01794.19 KFP01083.1 - 1.5e-13 50.9 17.2 6.4e-12 45.7 5.5 2.6 2 1 1 3 3 3 2 Ferric reductase like transmembrane component F420_oxidored PF03807.17 KFP01084.1 - 2.4e-18 66.5 0.0 4.6e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Ferric_reduct PF01794.19 KFP01084.1 - 3.3e-15 56.3 8.6 1e-13 51.5 3.6 2.4 1 1 1 2 2 2 2 Ferric reductase like transmembrane component NAD_binding_2 PF03446.15 KFP01084.1 - 1.3e-05 25.5 0.0 2.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KFP01084.1 - 0.0012 18.2 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KFP01084.1 - 0.016 15.3 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF2768 PF10966.8 KFP01084.1 - 0.054 13.9 3.1 0.23 11.9 3.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2768) IlvN PF07991.12 KFP01084.1 - 0.11 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 KFP01084.1 - 0.16 12.5 0.0 0.5 10.8 0.0 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding DUF997 PF06196.12 KFP01084.1 - 8.2 6.5 7.4 1.8 8.6 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF997) Rcd1 PF04078.13 KFP01085.1 - 0.0085 15.4 2.1 0.55 9.5 0.1 3.9 4 0 0 4 4 4 2 Cell differentiation family, Rcd1-like DUF4589 PF15252.6 KFP01086.1 - 0.095 12.7 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) MMR_HSR1 PF01926.23 KFP01087.1 - 9.3e-23 80.5 0.0 1.8e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.22 KFP01087.1 - 8.8e-18 64.4 7.0 5.8e-17 61.7 7.0 2.0 1 1 0 1 1 1 1 GTP1/OBG FeoB_N PF02421.18 KFP01087.1 - 1.5e-11 44.1 0.0 1.2e-10 41.2 0.0 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KFP01087.1 - 0.00018 21.1 0.0 0.0094 15.5 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KFP01087.1 - 0.00036 19.6 0.0 0.3 10.1 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB EIF_2_alpha PF07541.12 KFP01087.1 - 0.13 12.4 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit Dynamin_N PF00350.23 KFP01087.1 - 0.13 12.3 2.7 10 6.2 0.1 3.0 1 1 2 3 3 3 0 Dynamin family Claudin_2 PF13903.6 KFP01088.1 - 0.0074 16.1 13.2 0.078 12.7 13.2 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction EphA2_TM PF14575.6 KFP01089.1 - 8.4e-05 23.4 0.0 0.00012 22.9 0.0 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.12 KFP01089.1 - 0.00071 19.2 0.1 0.0011 18.6 0.1 1.4 1 0 0 1 1 1 1 CD34/Podocalyxin family FAM163 PF15069.6 KFP01089.1 - 0.001 19.6 1.0 0.0015 19.0 1.0 1.3 1 0 0 1 1 1 1 FAM163 family Cadherin_C_2 PF16492.5 KFP01089.1 - 0.0013 19.5 0.0 0.0021 18.8 0.0 1.4 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal Prominin PF05478.11 KFP01089.1 - 0.014 13.4 3.3 0.017 13.1 3.3 1.1 1 0 0 1 1 1 0 Prominin DUF4500 PF14937.6 KFP01089.1 - 0.015 15.3 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) TMEM154 PF15102.6 KFP01089.1 - 0.018 15.0 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Comm PF15957.5 KFP01089.1 - 0.019 15.3 0.1 0.032 14.6 0.1 1.3 1 0 0 1 1 1 0 Commissureless MAP17 PF15807.5 KFP01089.1 - 0.02 15.1 0.0 0.03 14.6 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 LRR19-TM PF15176.6 KFP01089.1 - 0.068 13.2 0.1 0.093 12.7 0.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain PAG PF15347.6 KFP01089.1 - 0.068 12.2 0.1 0.09 11.8 0.1 1.1 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched SKG6 PF08693.10 KFP01089.1 - 1.8 8.1 7.8 2.9 7.4 7.8 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Synaphin PF05835.12 KFP01089.1 - 3.5 7.9 12.3 4.6 7.5 12.3 1.1 1 0 0 1 1 1 0 Synaphin protein Synaptobrevin PF00957.21 KFP01089.1 - 4.8 7.0 6.6 1.5 8.6 3.6 1.7 2 0 0 2 2 2 0 Synaptobrevin IATP PF04568.12 KFP01089.1 - 9.2 6.8 8.4 14 6.2 8.4 1.2 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Pkinase PF00069.25 KFP01090.1 - 8.9e-68 228.5 0.0 1.1e-67 228.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP01090.1 - 3.3e-32 111.8 0.0 4.6e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFP01090.1 - 2.7e-05 23.3 0.0 8.8e-05 21.6 0.0 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFP01090.1 - 0.0018 17.6 0.0 0.0041 16.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFP01090.1 - 0.0032 17.4 0.0 0.088 12.7 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 KFP01090.1 - 0.054 13.1 0.0 4.6 6.8 0.0 2.4 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Frizzled PF01534.17 KFP01091.1 - 3.6e-141 469.9 16.8 4.1e-141 469.7 16.8 1.0 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region DUF2269 PF10027.9 KFP01091.1 - 3.1 7.8 12.4 0.58 10.2 0.2 2.8 1 1 0 2 2 2 0 Predicted integral membrane protein (DUF2269) DHHC PF01529.20 KFP01091.1 - 5.8 7.0 14.0 1.1 9.3 1.9 3.3 1 1 2 3 3 3 0 DHHC palmitoyltransferase p450 PF00067.22 KFP01092.1 - 2.1e-77 260.9 0.0 2.6e-77 260.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Archease PF01951.16 KFP01092.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Archease protein family (MTH1598/TM1083) NUDIX_5 PF16705.5 KFP01093.1 - 1.4e-85 285.5 0.0 2.4e-85 284.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX, or N-terminal NPxY motif-rich, region of KRIT FERM_M PF00373.18 KFP01093.1 - 8.9e-20 71.3 0.4 2.4e-19 69.9 0.1 2.0 2 0 0 2 2 2 1 FERM central domain Ank_2 PF12796.7 KFP01093.1 - 7.6e-16 58.5 0.0 1.1e-06 29.1 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP01093.1 - 1.9e-14 53.5 0.2 1.1e-09 38.3 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP01093.1 - 1.7e-11 44.4 0.5 5.9e-07 29.9 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KFP01093.1 - 3.6e-10 39.8 0.2 0.018 15.4 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KFP01093.1 - 7.9e-08 32.0 0.2 0.048 14.2 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat IBR PF01485.21 KFP01094.1 - 1e-20 73.7 20.6 2.1e-13 50.3 1.2 4.6 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain Ank_5 PF13857.6 KFP01094.1 - 8.1e-10 38.8 1.2 0.00019 21.7 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP01094.1 - 1.4e-09 38.4 0.4 7.4e-05 23.3 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFP01094.1 - 3.6e-09 36.7 0.1 0.0033 17.8 0.0 3.2 3 0 0 3 3 2 2 Ankyrin repeat Ank_4 PF13637.6 KFP01094.1 - 7.3e-07 29.6 0.1 0.0078 16.8 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP01094.1 - 7.5e-07 29.0 0.6 0.013 15.9 0.0 3.6 4 0 0 4 4 3 2 Ankyrin repeat zf-RING_UBOX PF13445.6 KFP01094.1 - 4.4e-05 23.4 30.6 0.00012 22.0 6.4 4.2 3 1 0 3 3 3 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFP01094.1 - 0.00078 19.2 4.9 0.00078 19.2 4.9 4.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP01094.1 - 0.0012 19.1 8.7 0.0012 19.1 8.7 4.1 3 1 0 3 3 3 2 Ring finger domain zf-C3HC4_4 PF15227.6 KFP01094.1 - 0.0044 17.2 6.5 0.0044 17.2 6.5 4.2 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KFP01094.1 - 0.0056 16.5 6.1 0.0056 16.5 6.1 4.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) UIM PF02809.20 KFP01094.1 - 0.13 12.3 0.7 0.39 10.7 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin interaction motif AAA PF00004.29 KFP01096.1 - 2.5e-58 196.2 0.0 1.2e-42 145.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KFP01096.1 - 5.7e-26 90.7 0.1 1.4e-25 89.5 0.1 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal PEX-2N PF09263.10 KFP01096.1 - 4.9e-20 71.6 0.2 3.6e-19 68.9 0.1 2.4 2 0 0 2 2 2 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KFP01096.1 - 1.7e-14 53.4 0.3 8.4e-10 38.3 0.0 3.4 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 KFP01096.1 - 2.4e-10 41.0 1.2 0.0021 18.4 0.0 3.5 2 1 1 3 3 3 2 AAA ATPase domain RNA_helicase PF00910.22 KFP01096.1 - 4.3e-07 30.3 0.0 0.006 17.0 0.0 3.2 3 0 0 3 3 3 2 RNA helicase AAA_5 PF07728.14 KFP01096.1 - 9.8e-07 28.9 0.2 0.043 13.8 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFP01096.1 - 2.3e-06 27.4 0.0 0.00063 19.5 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KFP01096.1 - 2.5e-06 27.7 0.0 0.086 13.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 KFP01096.1 - 7.9e-06 26.1 0.0 0.0023 18.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KFP01096.1 - 8.6e-06 25.1 0.0 0.00063 19.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.12 KFP01096.1 - 1.5e-05 25.0 7.6 0.016 15.1 1.6 4.9 4 1 0 4 4 4 1 NACHT domain AAA_14 PF13173.6 KFP01096.1 - 2.4e-05 24.4 0.0 0.044 13.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KFP01096.1 - 2.6e-05 24.0 0.0 0.15 11.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 KFP01096.1 - 2.7e-05 24.7 0.0 0.18 12.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 KFP01096.1 - 3.1e-05 23.4 0.2 0.028 13.6 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain Sigma54_activat PF00158.26 KFP01096.1 - 6e-05 22.8 0.1 0.13 12.0 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.6 KFP01096.1 - 0.00011 22.5 0.1 0.035 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFP01096.1 - 0.00019 21.1 1.6 0.0086 15.8 0.7 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SSE PF00437.20 KFP01096.1 - 0.00021 20.5 0.0 0.074 12.1 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein Sigma54_activ_2 PF14532.6 KFP01096.1 - 0.00026 21.1 0.0 0.14 12.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.6 KFP01096.1 - 0.00032 21.0 0.1 0.81 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 KFP01096.1 - 0.00035 20.6 0.2 0.81 9.7 0.1 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 KFP01096.1 - 0.0011 18.3 0.2 0.61 9.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 KFP01096.1 - 0.0017 17.9 0.0 0.66 9.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 KFP01096.1 - 0.0037 16.9 3.0 1.6 8.3 0.0 3.9 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 KFP01096.1 - 0.0038 16.6 0.3 1.9 7.8 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KFP01096.1 - 0.0068 15.8 0.2 0.77 9.1 0.0 2.4 2 0 0 2 2 2 1 KaiC ABC_tran PF00005.27 KFP01096.1 - 0.0079 16.7 6.2 0.12 12.9 0.8 3.5 3 1 1 4 4 3 1 ABC transporter AAA_24 PF13479.6 KFP01096.1 - 0.008 15.9 0.1 3.8 7.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFP01096.1 - 0.0096 16.2 5.1 2.9 8.1 0.3 3.9 2 2 1 3 3 3 1 AAA domain AAA_30 PF13604.6 KFP01096.1 - 0.012 15.3 0.4 1.3 8.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KFP01096.1 - 0.015 15.7 0.3 9 6.7 0.1 2.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KFP01096.1 - 0.039 13.1 0.1 3.6 6.7 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Molydop_binding PF01568.21 KFP01096.1 - 0.049 13.7 0.0 0.16 12.0 0.0 1.8 2 0 0 2 2 1 0 Molydopterin dinucleotide binding domain AAA_23 PF13476.6 KFP01096.1 - 0.054 14.0 1.1 0.28 11.7 0.3 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KFP01096.1 - 0.062 13.2 0.0 12 5.8 0.0 2.7 2 0 0 2 2 2 0 Rad17 P-loop domain APS_kinase PF01583.20 KFP01096.1 - 0.068 13.1 0.4 0.22 11.4 0.0 2.0 2 0 0 2 2 1 0 Adenylylsulphate kinase Hpr_kinase_C PF07475.12 KFP01096.1 - 0.14 11.7 0.9 0.83 9.2 0.1 2.2 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain CoaE PF01121.20 KFP01096.1 - 0.14 11.8 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 Dephospho-CoA kinase NTPase_1 PF03266.15 KFP01096.1 - 0.16 11.9 0.3 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 NTPase EF-hand_1 PF00036.32 KFP01098.1 - 1.1e-16 59.0 3.4 1.2e-06 27.6 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KFP01098.1 - 1.6e-14 52.5 1.0 5.9e-06 25.8 0.0 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 KFP01098.1 - 1.3e-13 51.2 3.0 4.9e-09 36.5 1.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP01098.1 - 1.1e-12 46.8 0.2 1e-05 24.8 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KFP01098.1 - 1.3e-09 37.8 5.9 0.021 14.7 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFP01098.1 - 0.0085 16.4 0.1 1.5 9.1 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Pkinase PF00069.25 KFP01099.1 - 4.8e-69 232.7 0.0 5.5e-69 232.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP01099.1 - 1.3e-35 123.0 0.0 2.5e-35 122.0 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFP01099.1 - 8.9e-07 29.1 0.2 0.0015 18.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KFP01099.1 - 1.8e-05 24.2 0.0 3.5e-05 23.3 0.0 1.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFP01099.1 - 0.00016 20.8 0.0 0.00028 19.9 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFP01099.1 - 0.002 17.5 0.1 0.0039 16.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KFP01099.1 - 0.022 14.4 0.0 0.056 13.0 0.0 1.6 1 1 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KFP01099.1 - 0.13 11.9 0.0 0.75 9.4 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Ig_3 PF13927.6 KFP01100.1 - 5.5e-21 74.9 0.3 1.5e-11 44.7 0.1 3.4 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFP01100.1 - 5.1e-16 58.5 0.0 2.7e-07 30.5 0.0 3.8 4 1 0 4 4 4 3 Immunoglobulin I-set domain ig PF00047.25 KFP01100.1 - 3.8e-13 49.4 0.0 7.8e-06 26.0 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFP01100.1 - 4.8e-13 49.2 0.1 2.6e-07 30.8 0.0 4.3 3 2 1 4 4 4 2 Immunoglobulin V-set domain Ig_2 PF13895.6 KFP01100.1 - 2.3e-11 43.9 0.1 2.1e-07 31.2 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin domain PKD_3 PF16820.5 KFP01100.1 - 0.13 12.0 0.0 0.56 10.0 0.0 2.0 2 0 0 2 2 2 0 PKD-like domain Ribosomal_S9 PF00380.19 KFP01100.1 - 0.21 12.1 0.0 0.45 11.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S9/S16 Vps54_N PF10475.9 KFP01101.1 - 1.1e-113 379.4 12.4 2.8e-113 378.0 12.4 1.8 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KFP01101.1 - 5.9e-96 320.8 3.0 5.9e-96 320.8 3.0 2.4 3 0 0 3 3 3 1 Protein of unknown function C-terminus (DUF2451) EF-G-binding_N PF07299.11 KFP01101.1 - 0.049 14.2 0.2 0.82 10.2 0.0 3.0 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal ERp29 PF07749.12 KFP01101.1 - 0.42 11.5 2.8 3 8.8 0.1 3.5 3 0 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain DUF4298 PF14131.6 KFP01101.1 - 4.1 7.4 9.8 1.2 9.1 0.1 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4298) SIX1_SD PF16878.5 KFP01101.1 - 9.1 6.8 11.9 5.9 7.4 0.2 4.9 5 1 0 5 5 5 0 Transcriptional regulator, SIX1, N-terminal SD domain 7tm_2 PF00002.24 KFP01102.1 - 3.8e-79 265.4 17.4 4.9e-79 265.1 17.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFP01102.1 - 3.1e-20 72.2 7.0 7.5e-20 71.0 7.0 1.7 1 0 0 1 1 1 1 Hormone receptor domain DUF5368 PF17336.2 KFP01102.1 - 1.7 8.9 7.5 0.64 10.2 0.1 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5368) Kunitz_BPTI PF00014.23 KFP01103.1 - 4.9e-57 190.0 32.5 1e-21 76.9 3.3 3.1 3 0 0 3 3 3 3 Kunitz/Bovine pancreatic trypsin inhibitor domain Prion PF00377.18 KFP01103.1 - 0.00025 20.8 4.1 0.00028 20.7 0.5 2.1 2 0 0 2 2 2 1 Prion/Doppel alpha-helical domain G-gamma PF00631.22 KFP01104.1 - 9.2e-21 73.6 0.1 1e-20 73.5 0.1 1.0 1 0 0 1 1 1 1 GGL domain HAUS5 PF14817.6 KFP01104.1 - 0.15 10.8 1.2 0.17 10.6 1.2 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Acyl-CoA_dh_1 PF00441.24 KFP01105.1 - 8e-40 136.5 0.3 1.1e-39 136.0 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFP01105.1 - 7.9e-22 77.3 0.0 1.4e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFP01105.1 - 7.2e-13 49.0 0.0 1.1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFP01105.1 - 4.8e-09 36.9 0.0 1.1e-08 35.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 KFP01105.1 - 0.19 11.3 0.0 0.55 9.8 0.0 1.8 2 1 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Sec20 PF03908.13 KFP01106.1 - 7.4e-05 22.6 0.1 9.9e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Sec20 Use1 PF09753.9 KFP01106.1 - 0.0007 19.4 0.0 0.00085 19.1 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 MCPsignal PF00015.21 KFP01106.1 - 0.065 13.0 0.0 0.078 12.8 0.0 1.0 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4407 PF14362.6 KFP01106.1 - 0.1 11.9 0.0 0.12 11.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Collagen PF01391.18 KFP01107.1 - 5.4e-166 538.5 678.4 3.1e-10 39.6 34.6 20.8 2 1 15 17 17 17 15 Collagen triple helix repeat (20 copies) COLFI PF01410.18 KFP01107.1 - 3.6e-107 357.0 0.1 4.4e-107 356.7 0.1 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Cas1_AcylT PF07779.12 KFP01109.1 - 1.9e-202 673.4 31.0 2.3e-202 673.1 31.0 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 KFP01109.1 - 0.041 13.6 0.1 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Sarcoglycan_2 PF05510.13 KFP01110.1 - 1e-127 426.1 0.0 1.2e-127 425.9 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon PDZ_5 PF17817.1 KFP01111.1 - 7.2e-28 96.7 2.1 4.5e-27 94.1 2.1 2.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFP01111.1 - 5.8e-14 52.2 1.8 1.6e-13 50.8 1.8 1.8 1 0 0 1 1 1 1 PDZ domain SAM_2 PF07647.17 KFP01111.1 - 6e-10 39.1 0.4 1.4e-09 37.9 0.4 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFP01111.1 - 1.2e-09 38.4 0.4 2.9e-09 37.2 0.4 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ_6 PF17820.1 KFP01111.1 - 8e-07 28.8 0.9 6.5e-06 25.9 0.3 2.8 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KFP01111.1 - 0.0033 17.7 0.4 0.013 15.8 0.4 2.0 1 0 0 1 1 1 1 PDZ domain Pox_A_type_inc PF04508.12 KFP01111.1 - 0.01 15.7 0.6 5.7 7.0 0.0 3.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat PKI PF02827.16 KFP01111.1 - 0.032 14.4 0.5 0.17 12.1 0.5 2.4 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor DUF4840 PF16128.5 KFP01111.1 - 0.096 12.7 0.3 0.25 11.4 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4840) SAM_PNT PF02198.16 KFP01111.1 - 0.097 12.6 1.3 0.13 12.3 0.2 1.8 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain DUF2407_C PF13373.6 KFP01111.1 - 0.23 11.6 8.0 0.87 9.8 7.2 2.4 1 1 0 1 1 1 0 DUF2407 C-terminal domain DUF4726 PF15855.5 KFP01111.1 - 0.32 11.2 1.8 2.9 8.1 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) DUF4407 PF14362.6 KFP01111.1 - 1.9 7.7 15.9 6.4 6.0 14.8 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 KFP01111.1 - 6.2 6.8 29.4 1.9 8.5 7.9 3.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Arylesterase PF01731.20 KFP01112.1 - 9.4e-39 131.5 1.7 1.6e-38 130.8 1.7 1.4 1 0 0 1 1 1 1 Arylesterase SGL PF08450.12 KFP01112.1 - 5.1e-07 29.5 0.0 7.3e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KFP01112.1 - 0.0014 18.7 0.1 0.0032 17.6 0.1 1.6 1 0 0 1 1 1 1 Strictosidine synthase Ank_2 PF12796.7 KFP01113.1 - 1.3e-23 83.4 22.4 1e-10 42.0 1.4 4.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP01113.1 - 7.5e-21 74.2 9.9 3.3e-07 30.7 0.5 6.1 2 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KFP01113.1 - 7e-18 64.2 13.3 0.039 14.4 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 KFP01113.1 - 3e-17 60.9 14.5 0.023 15.2 0.0 8.9 9 1 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 KFP01113.1 - 4.2e-15 55.6 10.4 0.0045 17.3 0.3 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFP01113.1 - 2.8e-10 40.4 3.8 5.9e-10 39.3 3.8 1.6 1 0 0 1 1 1 1 SOCS box BCDHK_Adom3 PF10436.9 KFP01114.1 - 3.2e-48 163.7 0.1 4.4e-48 163.2 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KFP01114.1 - 2.2e-13 50.7 0.0 3.9e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFP01114.1 - 0.0046 16.8 0.0 0.0078 16.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WD40 PF00400.32 KFP01115.1 - 5e-08 33.5 9.2 0.056 14.3 0.3 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP01115.1 - 0.053 13.8 0.1 0.92 9.9 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Mito_carr PF00153.27 KFP01116.1 - 8.1e-73 240.4 0.5 1.5e-26 92.2 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KFP01116.1 - 1.6e-09 38.1 1.1 0.00088 19.7 0.0 4.9 3 2 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KFP01116.1 - 2.3e-09 36.1 3.0 0.031 13.8 0.1 5.3 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 KFP01116.1 - 8.4e-09 34.7 1.4 0.0083 16.0 0.1 5.3 5 0 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 KFP01116.1 - 9.1e-07 28.6 0.9 0.16 11.8 0.0 4.3 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP01116.1 - 3e-05 23.3 0.2 0.94 9.1 0.0 4.2 5 0 0 5 5 5 2 EF hand DSS1_SEM1 PF05160.13 KFP01117.1 - 1.6e-13 50.5 11.2 1.7e-13 50.4 11.2 1.0 1 0 0 1 1 1 1 DSS1/SEM1 family Homeodomain PF00046.29 KFP01118.1 - 7.2e-21 73.8 2.4 9.8e-21 73.4 2.4 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP01118.1 - 0.0028 17.5 0.1 0.0054 16.6 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain DUF5524 PF17662.1 KFP01118.1 - 0.01 15.2 0.1 0.4 10.0 0.0 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5524) Homez PF11569.8 KFP01118.1 - 0.029 13.8 0.1 0.052 13.0 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez YdaS_antitoxin PF15943.5 KFP01118.1 - 0.049 13.5 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF3199 PF11436.8 KFP01118.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3199) DLL_N PF12413.8 KFP01119.1 - 3.4e-26 92.3 23.1 3.4e-26 92.3 23.1 1.9 2 0 0 2 2 2 1 Homeobox protein distal-less-like N terminal Homeodomain PF00046.29 KFP01119.1 - 3.2e-20 71.7 2.5 4.9e-20 71.1 2.5 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP01119.1 - 0.0066 16.3 0.1 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 KFP01119.1 - 0.069 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Tachykinin PF02202.16 KFP01121.1 - 2.1e-10 39.4 1.1 0.00077 19.1 0.9 2.4 2 0 0 2 2 2 2 Tachykinin family Pro-rich PF15240.6 KFP01121.1 - 0.08 13.2 0.0 0.08 13.2 0.0 1.2 1 0 0 1 1 1 0 Proline-rich DIM PF08194.12 KFP01121.1 - 0.37 11.0 1.1 0.53 10.5 1.1 1.2 1 0 0 1 1 1 0 DIM protein Asn_synthase PF00733.21 KFP01122.1 - 1e-83 282.0 0.3 4.2e-80 270.1 0.3 2.1 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 KFP01122.1 - 8.3e-26 90.3 0.0 1.4e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KFP01122.1 - 4.8e-19 68.9 0.0 1e-18 67.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KFP01122.1 - 5.4e-08 32.6 0.0 1.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KFP01122.1 - 0.009 15.2 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 NAD synthase QueC PF06508.13 KFP01122.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KFP01122.1 - 0.088 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Fringe PF02434.16 KFP01123.1 - 8.9e-15 54.8 2.2 2.9e-14 53.1 1.4 2.0 2 1 0 2 2 2 1 Fringe-like Galactosyl_T PF01762.21 KFP01123.1 - 5.2e-09 36.2 0.8 6.5e-05 22.8 0.6 2.2 1 1 1 2 2 2 2 Galactosyltransferase VWA PF00092.28 KFP01124.1 - 8.7e-61 205.2 7.9 2.2e-36 125.7 0.8 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain Collagen PF01391.18 KFP01124.1 - 2.8e-58 193.5 291.1 1.1e-07 31.4 24.0 11.8 3 1 7 10 10 10 8 Collagen triple helix repeat (20 copies) VWA_2 PF13519.6 KFP01124.1 - 3.9e-30 104.6 3.2 1.4e-18 67.4 0.2 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.6 KFP01124.1 - 2.7e-09 37.1 1.0 0.00013 21.9 0.1 3.0 3 0 0 3 3 3 2 von Willebrand factor type A domain DUF1194 PF06707.11 KFP01124.1 - 0.00031 20.0 0.9 0.1 11.8 0.0 2.8 2 2 0 2 2 2 2 Protein of unknown function (DUF1194) VWA_CoxE PF05762.14 KFP01124.1 - 0.00061 19.3 0.0 0.0035 16.8 0.0 1.9 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein Phage_Capsid_P3 PF09018.11 KFP01124.1 - 0.062 12.1 0.1 0.092 11.5 0.1 1.1 1 0 0 1 1 1 0 P3 major capsid protein Rep_fac-A_3 PF08661.11 KFP01125.1 - 2.3e-29 101.8 0.0 2.7e-29 101.6 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 SUKH-3 PF14433.6 KFP01125.1 - 0.098 13.1 0.1 19 5.7 0.0 2.6 1 1 2 3 3 3 0 SUKH-3 immunity protein DUF356 PF04009.12 KFP01125.1 - 0.19 12.0 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF356) DUF2464 PF10240.9 KFP01126.1 - 0.0093 15.6 0.0 0.0097 15.5 0.0 1.0 1 0 0 1 1 1 1 Multivesicular body subunit 12 FAM117 PF15388.6 KFP01128.1 - 7.3e-124 413.3 19.7 7.3e-124 413.3 19.7 1.7 2 0 0 2 2 2 1 Protein Family FAM117 Arfaptin PF06456.13 KFP01129.1 - 5.1e-89 297.8 11.6 8.7e-89 297.0 11.6 1.4 1 0 0 1 1 1 1 Arfaptin-like domain ICA69 PF04629.14 KFP01129.1 - 1.1e-59 202.8 19.0 1.8e-40 139.9 10.1 2.8 1 1 1 2 2 2 2 Islet cell autoantigen ICA69, C-terminal domain BAR_2 PF10455.9 KFP01129.1 - 0.0011 18.1 3.2 0.0014 17.8 2.6 1.7 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Ead_Ea22 PF13935.6 KFP01129.1 - 0.49 11.1 3.4 1.7 9.3 3.4 2.2 1 1 0 1 1 1 0 Ead/Ea22-like protein Neurexophilin PF06312.12 KFP01130.1 - 7.2e-112 372.0 2.7 8.9e-112 371.6 2.7 1.1 1 0 0 1 1 1 1 Neurexophilin Filamin PF00630.19 KFP01130.1 - 0.059 14.2 0.0 0.22 12.3 0.0 1.9 2 0 0 2 2 2 0 Filamin/ABP280 repeat NigD_C PF17415.2 KFP01130.1 - 0.063 13.3 0.1 0.74 9.9 0.0 2.2 2 0 0 2 2 2 0 NigD-like C-terminal beta sandwich domain B12D PF06522.11 KFP01131.1 - 1e-31 108.5 0.0 1.1e-31 108.4 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit TSP_1 PF00090.19 KFP01132.1 - 2e-64 213.6 221.5 6.6e-13 48.7 7.1 23.6 25 1 0 25 25 25 18 Thrombospondin type 1 domain DUF1356 PF07092.12 KFP01133.1 - 8.2e-118 391.8 6.8 1e-117 391.4 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) Anti-TRAP PF15777.5 KFP01133.1 - 0.026 14.5 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein DnaJ_CXXCXGXG PF00684.19 KFP01133.1 - 0.05 14.0 0.3 0.15 12.5 0.1 1.9 2 0 0 2 2 2 0 DnaJ central domain EGF PF00008.27 KFP01134.1 - 5.8e-15 55.3 57.9 0.00011 22.4 7.7 4.5 4 0 0 4 4 4 4 EGF-like domain EGF_2 PF07974.13 KFP01134.1 - 9.9e-14 51.4 67.8 0.0013 19.0 13.2 4.1 4 0 0 4 4 4 4 EGF-like domain hEGF PF12661.7 KFP01134.1 - 1.9e-08 34.6 33.7 0.00011 22.7 4.2 6.3 8 0 0 8 8 8 4 Human growth factor-like EGF Laminin_EGF PF00053.24 KFP01134.1 - 1.5 9.1 50.0 2.4 8.4 10.8 4.2 1 1 3 4 4 4 0 Laminin EGF domain EGF_2 PF07974.13 KFP01135.1 - 3.9e-20 71.9 77.6 0.00018 21.8 11.1 5.1 5 0 0 5 5 5 5 EGF-like domain EGF PF00008.27 KFP01135.1 - 3.7e-15 55.9 74.2 0.00014 22.1 10.3 5.8 5 0 0 5 5 5 5 EGF-like domain hEGF PF12661.7 KFP01135.1 - 1.1e-09 38.5 81.1 0.0014 19.2 6.4 7.4 8 0 0 8 8 8 5 Human growth factor-like EGF Laminin_EGF PF00053.24 KFP01135.1 - 1.4 9.1 65.4 7.3 6.8 5.4 5.2 2 1 3 5 5 5 0 Laminin EGF domain DSL PF01414.19 KFP01135.1 - 9.5 6.6 53.3 1.9 8.8 13.1 3.5 2 1 1 3 3 3 0 Delta serrate ligand EGF PF00008.27 KFP01136.1 - 2.2e-05 24.7 41.2 0.0011 19.2 6.4 4.4 4 0 0 4 4 4 3 EGF-like domain hEGF PF12661.7 KFP01136.1 - 0.011 16.3 16.5 0.014 16.0 6.3 5.5 5 2 1 6 6 6 0 Human growth factor-like EGF EGF_2 PF07974.13 KFP01136.1 - 1.6 9.2 47.8 0.24 11.8 6.2 4.5 4 0 0 4 4 4 0 EGF-like domain VWD PF00094.25 KFP01137.1 - 9.6e-05 22.7 1.0 0.00017 21.9 1.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type D domain Gelsolin PF00626.22 KFP01138.1 - 2.7e-86 283.5 0.7 6e-18 64.5 0.0 6.3 6 0 0 6 6 6 6 Gelsolin repeat Arf PF00025.21 KFP01139.1 - 4.2e-67 225.0 0.0 4.9e-67 224.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFP01139.1 - 2.1e-17 63.2 0.0 2.3e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP01139.1 - 4.1e-17 62.5 0.1 5.4e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFP01139.1 - 5.6e-12 45.5 0.1 5.6e-12 45.5 0.1 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFP01139.1 - 4e-08 32.8 0.4 1.4e-06 27.8 0.1 2.3 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 KFP01139.1 - 1.3e-07 31.6 0.1 1.9e-07 31.2 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP01139.1 - 0.0001 21.9 0.1 0.00034 20.2 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFP01139.1 - 0.00013 21.4 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 KFP01139.1 - 0.006 16.4 0.0 0.015 15.1 0.0 1.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein 6PF2K PF01591.18 KFP01139.1 - 0.026 13.8 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_28 PF13521.6 KFP01139.1 - 0.042 14.1 0.1 0.3 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain ETS_PEA3_N PF04621.13 KFP01141.1 - 5.1e-143 477.1 21.2 6.8e-143 476.7 21.2 1.2 1 0 0 1 1 1 1 PEA3 subfamily ETS-domain transcription factor N terminal domain Ets PF00178.22 KFP01141.1 - 2.1e-38 130.6 0.2 3.6e-38 129.9 0.2 1.4 1 0 0 1 1 1 1 Ets-domain DAGK_acc PF00609.19 KFP01142.1 - 1e-55 188.4 0.0 2.3e-55 187.3 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAG_kinase_N PF14513.6 KFP01142.1 - 5.4e-47 160.1 0.8 3.2e-44 151.1 0.2 3.0 2 1 0 2 2 2 1 Diacylglycerol kinase N-terminus DAGK_cat PF00781.24 KFP01142.1 - 1.6e-27 95.6 0.0 3.1e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 KFP01142.1 - 3.8e-21 74.7 34.6 1.2e-12 47.5 7.1 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_1 PF00036.32 KFP01142.1 - 1.8e-13 49.0 0.7 4.7e-06 25.8 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFP01142.1 - 4.5e-10 39.8 0.5 1.4e-09 38.3 0.5 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP01142.1 - 1.4e-09 37.1 0.4 2.9e-05 23.6 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KFP01142.1 - 1.3e-08 34.0 0.3 0.0049 16.3 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFP01142.1 - 1.2e-06 28.3 3.6 0.011 15.6 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFP01142.1 - 0.0002 21.6 0.2 0.0018 18.6 0.2 2.5 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region C1_2 PF03107.16 KFP01142.1 - 0.3 11.4 20.7 0.34 11.3 4.7 2.5 2 0 0 2 2 2 0 C1 domain FA_hydroxylase PF04116.13 KFP01144.1 - 4e-28 98.4 11.4 8.4e-28 97.4 11.4 1.6 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Homeodomain PF00046.29 KFP01145.1 - 1.5e-14 53.5 7.2 1.5e-14 53.5 7.2 1.9 2 0 0 2 2 2 1 Homeodomain ISPD_C PF18706.1 KFP01146.1 - 1.1e-45 155.3 6.2 1.7e-45 154.7 6.2 1.3 1 0 0 1 1 1 1 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain IspD PF01128.19 KFP01146.1 - 2.6e-30 105.8 0.0 4.5e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase TPALS PF18178.1 KFP01146.1 - 0.042 13.3 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family Ubiq-Cytc-red_N PF09165.10 KFP01146.1 - 0.051 14.5 0.4 29 5.6 0.0 3.2 3 0 0 3 3 3 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal MIP-T3 PF10243.9 KFP01146.1 - 0.096 12.7 0.2 6.6 6.8 0.0 2.9 4 0 0 4 4 4 0 Microtubule-binding protein MIP-T3 CH-like domain Sclerostin PF05463.11 KFP01147.1 - 5.3e-101 336.4 6.4 5.9e-101 336.2 6.4 1.0 1 0 0 1 1 1 1 Sclerostin (SOST) DAN PF03045.15 KFP01147.1 - 1.4e-14 54.0 1.9 2.1e-14 53.5 1.9 1.3 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.22 KFP01147.1 - 4.2e-05 23.8 7.6 0.00022 21.5 7.6 1.9 1 1 0 1 1 1 1 Cystine-knot domain LRR_9 PF14580.6 KFP01148.1 - 6.2e-19 68.2 2.4 8.9e-18 64.4 2.0 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 KFP01148.1 - 9.6e-15 54.5 10.9 1.8e-05 25.0 0.0 3.3 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP01148.1 - 1.6e-08 34.2 30.0 1.8e-05 24.4 8.8 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 KFP01148.1 - 0.0097 15.9 8.5 0.87 9.8 0.2 4.1 4 1 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 KFP01148.1 - 0.012 16.1 10.9 15 6.6 0.1 4.8 4 1 0 4 4 4 0 Leucine Rich Repeat Ank_2 PF12796.7 KFP01149.1 - 2.6e-12 47.1 0.2 2.5e-10 40.8 0.3 2.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFP01149.1 - 2.6e-11 43.4 0.2 2.9e-07 30.6 0.2 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFP01149.1 - 4.7e-10 38.8 0.2 2.3e-07 30.5 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KFP01149.1 - 9.9e-10 38.5 0.6 3.3e-06 27.3 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) zf-MYND PF01753.18 KFP01149.1 - 1.7e-09 37.6 12.7 1.7e-09 37.6 12.7 2.5 2 0 0 2 2 2 1 MYND finger Ank_4 PF13637.6 KFP01149.1 - 1.9e-09 37.8 0.2 1.3e-07 32.0 0.1 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) PolC_DP2 PF03833.13 KFP01149.1 - 0.15 9.9 6.1 0.23 9.3 6.1 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-Mss51 PF13824.6 KFP01149.1 - 0.18 11.9 5.6 0.64 10.2 5.6 1.9 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 ATP-synt_E PF05680.12 KFP01149.1 - 1.1 9.6 4.9 2 8.8 4.9 1.4 1 0 0 1 1 1 0 ATP synthase E chain zf-C6H2 PF15801.5 KFP01149.1 - 7.3 7.0 18.9 1.4 9.3 12.1 2.5 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding W2 PF02020.18 KFP01150.1 - 4.3e-21 74.8 8.7 7.8e-21 74.0 4.4 2.9 3 1 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Tetraspanin PF00335.20 KFP01151.1 - 4.4e-15 56.0 13.2 5.8e-15 55.6 13.2 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF5373 PF17343.2 KFP01151.1 - 0.0088 15.9 2.3 0.012 15.4 2.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5373) Ac76 PF05814.11 KFP01151.1 - 0.052 13.5 2.1 0.087 12.8 2.1 1.4 1 0 0 1 1 1 0 Orf76 (Ac76) DUF2981 PF11200.8 KFP01151.1 - 0.056 13.2 1.2 0.065 13.0 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) NICE-3 PF07406.11 KFP01151.1 - 0.39 10.7 0.0 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 NICE-3 protein DUF423 PF04241.15 KFP01151.1 - 4.5 7.5 10.5 0.8 10.0 1.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF423) Thioredoxin_7 PF13899.6 KFP01152.1 - 4.2e-19 68.5 0.0 8.6e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KFP01152.1 - 0.033 14.6 0.1 0.23 11.9 0.1 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFP01153.1 - 1.5e-25 89.2 0.3 3.6e-25 88.0 0.1 1.6 2 0 0 2 2 2 1 Thioredoxin-like Thioredox_DsbH PF03190.15 KFP01153.1 - 3.2e-06 27.2 0.1 4.3e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.6 KFP01153.1 - 6.7e-06 26.5 0.2 2.1e-05 24.9 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain PXA PF02194.15 KFP01154.1 - 8.1e-53 179.1 1.1 4.8e-51 173.3 0.3 2.9 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 KFP01154.1 - 1.2e-24 87.1 1.0 6.2e-23 81.5 0.1 3.9 3 1 0 3 3 3 1 Sorting nexin C terminal PX PF00787.24 KFP01154.1 - 5.3e-23 81.2 0.6 5.3e-23 81.2 0.6 2.4 2 0 0 2 2 2 1 PX domain RGS PF00615.19 KFP01154.1 - 4.5e-21 75.3 4.5 1.8e-19 70.1 0.2 3.6 3 0 0 3 3 3 1 Regulator of G protein signaling domain Xpo1 PF08389.12 KFP01154.1 - 0.033 14.3 2.2 0.18 11.9 0.0 3.2 4 0 0 4 4 4 0 Exportin 1-like protein DUF1664 PF07889.12 KFP01154.1 - 0.63 10.1 4.3 23 5.1 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 KFP01154.1 - 2.3 8.6 8.4 0.27 11.6 0.4 3.4 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Yae1_N PF09811.9 KFP01155.1 - 7.7e-18 63.9 63.5 1.8e+04 -28.3 63.5 6.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Hist_deacetyl PF00850.19 KFP01156.1 - 7.6e-74 249.0 0.0 7.6e-74 249.0 0.0 2.6 3 0 0 3 3 3 1 Histone deacetylase domain HDAC4_Gln PF12203.8 KFP01156.1 - 5.8e-35 119.3 47.7 5.8e-35 119.3 47.7 3.6 3 0 0 3 3 3 1 Glutamine rich N terminal domain of histone deacetylase 4 U-box PF04564.15 KFP01156.1 - 1 9.6 3.4 20 5.5 0.1 3.5 3 0 0 3 3 3 0 U-box domain HLH PF00010.26 KFP01157.1 - 1.6e-16 60.0 0.3 2.5e-16 59.4 0.3 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_51 PF18558.1 KFP01157.1 - 0.00074 19.3 0.1 0.0011 18.9 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain DUF773 PF05600.12 KFP01157.1 - 0.005 15.6 0.5 0.0055 15.5 0.5 1.0 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 GDH_N PF12466.8 KFP01157.1 - 0.041 14.1 0.1 0.055 13.7 0.1 1.3 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal L27 PF02828.16 KFP01157.1 - 0.071 12.9 0.1 4.6 7.1 0.1 2.4 2 0 0 2 2 2 0 L27 domain Toxin_trans PF07952.12 KFP01157.1 - 0.14 11.3 0.1 0.15 11.1 0.1 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain HLH PF00010.26 KFP01158.1 - 4.5e-17 61.7 0.6 4.5e-17 61.7 0.6 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Yae1_N PF09811.9 KFP01159.1 - 5.8e-10 38.7 43.6 1.8e+04 -9.4 43.6 5.2 1 1 0 1 1 1 0 Essential protein Yae1, N terminal RPA43_OB PF17875.1 KFP01160.1 - 5.1e-07 30.4 11.1 0.00061 20.4 11.1 3.2 1 1 0 1 1 1 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 KFP01160.1 - 0.00011 22.5 0.1 0.0002 21.7 0.1 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 ABC_membrane_3 PF13748.6 KFP01161.1 - 0.066 12.4 0.5 0.12 11.6 0.5 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region ZU5 PF00791.20 KFP01162.1 - 3.5e-05 24.1 0.2 7.3e-05 23.0 0.2 1.6 1 0 0 1 1 1 1 ZU5 domain Death PF00531.22 KFP01162.1 - 0.00011 22.3 0.6 0.66 10.2 0.1 3.0 1 1 1 2 2 2 2 Death domain SH3_2 PF07653.17 KFP01162.1 - 0.001 18.7 0.1 0.0019 17.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain DDT PF02791.17 KFP01162.1 - 0.14 12.5 0.0 0.48 10.8 0.0 1.9 2 0 0 2 2 2 0 DDT domain Integrin_beta PF00362.18 KFP01163.1 - 2e-97 325.7 0.0 3.3e-97 325.0 0.0 1.3 1 0 0 1 1 1 1 Integrin beta chain VWA domain EGF_2 PF07974.13 KFP01163.1 - 1.1e-07 32.1 35.6 1.6e-05 25.1 13.8 4.9 5 0 0 5 5 5 3 EGF-like domain Sigma_reg_N PF13800.6 KFP01163.1 - 0.18 12.1 1.0 0.39 11.0 1.0 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal I-EGF_1 PF18372.1 KFP01163.1 - 0.41 10.8 45.1 0.088 12.9 7.1 4.2 4 0 0 4 4 4 0 Integrin beta epidermal growth factor like domain 1 EGF_Tenascin PF18720.1 KFP01163.1 - 6 7.0 35.2 0.062 13.4 1.3 4.3 4 0 0 4 4 4 0 Tenascin EGF domain zf-H2C2_2 PF13465.6 KFP01167.1 - 1.1e-15 57.3 8.8 4.2e-09 36.4 2.5 4.4 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFP01167.1 - 3.1e-13 49.4 30.9 3.5e-06 27.1 1.1 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP01167.1 - 1.1e-08 35.2 28.9 7e-05 23.3 2.8 3.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFP01167.1 - 0.00015 21.6 16.8 0.0089 16.0 2.2 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP01167.1 - 0.0016 18.7 4.0 0.43 10.9 1.1 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KFP01167.1 - 0.0065 16.7 6.6 0.01 16.1 4.1 2.2 2 1 0 2 2 2 1 C2H2-type zinc ribbon DUF971 PF06155.12 KFP01167.1 - 0.096 13.3 1.8 3.9 8.2 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF971) zf-LYAR PF08790.11 KFP01167.1 - 0.24 11.3 3.6 6.8 6.7 0.3 2.8 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf_C2H2_ZHX PF18387.1 KFP01167.1 - 0.87 9.3 3.6 8.3 6.1 0.0 2.6 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_5 PF13909.6 KFP01167.1 - 1.9 8.3 16.9 2.2 8.1 2.5 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-met PF12874.7 KFP01167.1 - 2 8.9 6.2 7.7 7.1 1.2 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Zn_Tnp_IS1 PF03811.13 KFP01167.1 - 3 7.6 9.0 2.4 7.9 2.2 2.5 2 0 0 2 2 2 0 InsA N-terminal domain zf-4CXXC_R1 PF10497.9 KFP01168.1 - 3.6e-37 126.6 9.3 6.2e-37 125.8 9.3 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 IL6 PF00489.17 KFP01169.1 - 1.6e-41 142.0 2.4 1.8e-41 141.8 2.4 1.0 1 0 0 1 1 1 1 Interleukin-6/G-CSF/MGF family IL11 PF07400.11 KFP01169.1 - 0.0044 16.7 0.2 0.0051 16.5 0.2 1.1 1 0 0 1 1 1 1 Interleukin 11 Hyccin PF09790.9 KFP01170.1 - 1e-129 432.3 0.7 1.6e-129 431.6 0.7 1.3 1 0 0 1 1 1 1 Hyccin Kelch_1 PF01344.25 KFP01171.1 - 8.2e-46 153.4 13.7 9.9e-13 47.5 0.5 5.8 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 KFP01171.1 - 3e-34 117.2 1.0 3.1e-33 114.0 0.1 2.7 3 0 0 3 3 3 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFP01171.1 - 9.6e-29 98.7 7.0 4.8e-09 36.2 0.0 6.3 2 1 4 6 6 6 5 Kelch motif BTB PF00651.31 KFP01171.1 - 1.2e-28 99.5 1.2 1.2e-28 99.5 1.2 1.8 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.6 KFP01171.1 - 2.1e-22 78.8 0.1 1.4e-08 34.6 0.0 5.5 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP01171.1 - 2.7e-21 74.7 6.2 3.4e-06 26.8 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KFP01171.1 - 6.8e-11 42.2 4.8 0.00041 20.6 0.0 5.7 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP01171.1 - 3.1e-09 36.6 3.3 0.12 12.4 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Glyoxal_oxid_N PF07250.11 KFP01171.1 - 0.038 13.2 1.5 0.2 10.8 0.3 2.5 2 1 1 3 3 3 0 Glyoxal oxidase N-terminus UvrD-helicase PF00580.21 KFP01171.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain ADPRTs_Tse2 PF18648.1 KFP01171.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Tse2 ADP-ribosyltransferase toxins PKD PF00801.20 KFP01173.1 - 8e-10 38.4 0.1 1.5e-08 34.4 0.1 2.5 2 0 0 2 2 2 1 PKD domain DUF4231 PF14015.6 KFP01173.1 - 0.049 14.1 0.1 0.11 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) RsfS PF02410.15 KFP01174.1 - 1.1e-28 99.5 0.0 1.4e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation KH_1 PF00013.29 KFP01175.1 - 9.1e-59 195.2 13.3 3.3e-15 55.7 0.1 5.0 5 0 0 5 5 5 4 KH domain RRM_1 PF00076.22 KFP01175.1 - 2.9e-17 62.2 0.0 6.7e-09 35.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_2 PF07650.17 KFP01175.1 - 5.8e-16 58.1 5.8 0.0034 17.2 0.1 4.6 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 KFP01175.1 - 7.4e-15 54.6 0.5 0.0024 17.7 0.0 4.7 4 0 0 4 4 4 4 KH domain KH_5 PF13184.6 KFP01175.1 - 6e-07 29.5 5.9 0.61 10.2 0.1 4.3 4 0 0 4 4 4 3 NusA-like KH domain MOEP19 PF16005.5 KFP01175.1 - 1.3e-05 25.1 0.1 0.14 12.1 0.0 4.3 5 0 0 5 5 5 1 KH-like RNA-binding domain RRM_5 PF13893.6 KFP01175.1 - 4.1e-05 23.2 0.0 0.023 14.3 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4041 PF13250.6 KFP01175.1 - 0.26 11.2 1.2 0.52 10.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) RRM_1 PF00076.22 KFP01176.1 - 7.6e-20 70.5 0.0 1.1e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFP01176.1 - 0.18 11.9 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Apt1 PF10351.9 KFP01176.1 - 0.29 9.9 11.8 0.31 9.9 11.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 KFP01176.1 - 1.2 7.9 5.3 1.4 7.6 5.3 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 KFP01176.1 - 1.6 7.5 6.3 1.8 7.2 6.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4525 PF15027.6 KFP01177.1 - 5.4e-75 249.6 1.3 6.7e-75 249.3 1.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4525) DUF4407 PF14362.6 KFP01177.1 - 0.0011 18.4 1.1 0.03 13.7 0.1 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) FAM221 PF14753.6 KFP01178.1 - 2.7e-93 311.0 5.3 3.2e-93 310.8 5.3 1.1 1 0 0 1 1 1 1 Protein FAM221A/B TUDOR PF00567.24 KFP01179.1 - 1.1e-23 83.6 0.4 2.7e-23 82.3 0.4 1.8 1 0 0 1 1 1 1 Tudor domain Pkinase PF00069.25 KFP01179.1 - 5.4e-16 58.7 0.1 2.7e-15 56.4 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP01179.1 - 7.8e-12 45.0 0.0 1.8e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Phage_int_SAM_1 PF02899.17 KFP01179.1 - 0.005 17.1 0.2 0.012 15.9 0.2 1.7 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain SNase PF00565.17 KFP01179.1 - 0.0088 16.5 0.0 0.032 14.7 0.0 1.9 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Agenet PF05641.12 KFP01179.1 - 0.023 15.1 0.0 0.077 13.5 0.0 1.9 1 0 0 1 1 1 0 Agenet domain SMN PF06003.12 KFP01179.1 - 0.027 13.8 0.8 0.078 12.2 0.0 2.1 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) PHM7_cyt PF14703.6 KFP01179.1 - 0.12 12.6 0.1 0.12 12.6 0.1 3.7 4 1 0 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter Hormone_3 PF00159.18 KFP01180.1 - 5.3e-19 68.0 1.1 1e-18 67.1 1.1 1.5 1 0 0 1 1 1 1 Pancreatic hormone peptide Gasdermin PF04598.12 KFP01181.1 - 5.9e-90 300.9 1.9 7.9e-90 300.5 1.9 1.2 1 0 0 1 1 1 1 Gasdermin pore forming domain Gasdermin_C PF17708.1 KFP01181.1 - 1.5e-44 152.2 8.9 1.5e-44 152.2 8.9 2.0 3 0 0 3 3 3 1 Gasdermin PUB domain Oxysterol_BP PF01237.18 KFP01182.1 - 4e-130 434.0 1.8 4e-130 434.0 1.8 2.0 2 1 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.6 KFP01182.1 - 4.5e-12 46.1 0.1 1.5e-11 44.4 0.1 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFP01182.1 - 4.5e-07 30.3 2.5 9e-07 29.4 1.4 2.2 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KFP01182.1 - 3.5 8.1 5.9 13 6.3 0.1 3.1 1 1 1 2 2 2 0 Pleckstrin homology domain Cytochrom_C PF00034.21 KFP01183.1 - 1.6e-13 51.6 0.0 2.1e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KFP01183.1 - 2.6e-06 27.7 2.3 1.2e-05 25.6 2.3 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KFP01183.1 - 0.00023 20.9 3.5 0.0025 17.5 3.5 2.2 1 1 0 1 1 1 1 Cytochrome c-550 domain FARP PF01581.16 KFP01184.1 - 0.75 10.6 3.2 48 5.1 0.0 3.5 3 0 0 3 3 3 0 FMRFamide related peptide family bZIP_Maf PF03131.17 KFP01187.1 - 3e-21 75.7 4.4 3e-21 75.7 4.4 1.6 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_1 PF00170.21 KFP01187.1 - 9.5e-10 38.4 12.4 2e-09 37.4 12.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFP01187.1 - 7e-07 29.2 7.7 1.6e-06 28.1 7.7 1.6 1 0 0 1 1 1 1 Basic region leucine zipper TolA_bind_tri PF16331.5 KFP01187.1 - 0.0028 17.7 2.2 0.0056 16.7 2.2 1.5 1 0 0 1 1 1 1 TolA binding protein trimerisation DUF724 PF05266.14 KFP01187.1 - 0.003 17.4 1.8 0.0054 16.6 1.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF724) Seryl_tRNA_N PF02403.22 KFP01187.1 - 0.15 12.3 4.8 0.33 11.2 4.8 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.11 KFP01187.1 - 0.29 11.6 2.1 0.6 10.5 2.1 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) KRAP_IP3R_bind PF14722.6 KFP01187.1 - 1.1 9.0 4.8 0.65 9.7 0.5 2.5 2 0 0 2 2 2 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain RRM_1 PF00076.22 KFP01188.1 - 1.2e-32 111.5 0.0 4.8e-15 55.1 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP01188.1 - 8.2e-09 35.5 0.1 0.00068 19.7 0.0 2.6 2 2 0 2 2 2 2 RNA recognition motif OB_RNB PF08206.11 KFP01188.1 - 0.033 13.9 0.5 1.2 8.9 0.1 2.7 2 0 0 2 2 2 0 Ribonuclease B OB domain Chromo_shadow PF01393.19 KFP01189.1 - 3.4e-33 113.5 0.1 1.4e-29 101.9 0.0 2.4 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 KFP01189.1 - 1.4e-20 72.9 0.1 1.1e-16 60.5 0.1 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 KFP01189.1 - 0.0092 16.1 0.1 0.053 13.7 0.1 2.1 2 0 0 2 2 2 1 Polycomb-like MTF2 factor 2 PX PF00787.24 KFP01190.1 - 1.5e-24 86.2 2.5 1.9e-24 85.8 2.5 1.2 1 0 0 1 1 1 1 PX domain Homeodomain PF00046.29 KFP01191.1 - 1.2e-22 79.4 7.4 1.6e-22 79.1 7.4 1.1 1 0 0 1 1 1 1 Homeodomain YcgR PF07317.12 KFP01191.1 - 0.014 15.2 0.2 0.37 10.7 0.0 2.1 1 1 1 2 2 2 0 Flagellar regulator YcgR Homeobox_KN PF05920.11 KFP01191.1 - 0.072 13.0 3.9 0.083 12.8 0.6 2.2 2 0 0 2 2 2 0 Homeobox KN domain DUF4074 PF13293.6 KFP01192.1 - 3.5e-37 126.5 8.8 3.5e-37 126.5 8.8 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4074) Homeodomain PF00046.29 KFP01192.1 - 1.5e-21 76.0 5.2 3.1e-21 75.0 5.2 1.6 1 0 0 1 1 1 1 Homeodomain Homeodomain PF00046.29 KFP01193.1 - 1.7e-21 75.8 9.1 1.7e-21 75.8 9.1 1.7 2 0 0 2 2 2 1 Homeodomain Homeodomain PF00046.29 KFP01194.1 - 8.1e-22 76.8 8.5 1.3e-21 76.2 8.5 1.3 1 0 0 1 1 1 1 Homeodomain DUF2209 PF09974.9 KFP01194.1 - 0.18 12.1 0.1 0.29 11.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Homeodomain PF00046.29 KFP01195.1 - 3.5e-22 78.0 6.7 3.9e-22 77.8 6.7 1.0 1 0 0 1 1 1 1 Homeodomain HTH_23 PF13384.6 KFP01195.1 - 0.0038 17.0 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain Homeobox_KN PF05920.11 KFP01195.1 - 0.048 13.6 1.4 0.059 13.3 1.4 1.4 1 1 0 1 1 1 0 Homeobox KN domain CI-B14_5a PF07347.12 KFP01195.1 - 0.072 13.0 0.0 0.094 12.6 0.0 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Homeodomain PF00046.29 KFP01196.1 - 2.8e-20 71.9 6.3 5.3e-20 71.0 6.3 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP01196.1 - 0.11 12.5 0.3 0.11 12.5 0.3 1.9 2 0 0 2 2 2 0 Homeobox KN domain DUF3528 PF12045.8 KFP01197.1 - 2e-64 216.5 0.8 2.9e-64 215.9 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3528) Homeodomain PF00046.29 KFP01197.1 - 5.6e-20 71.0 7.7 9.2e-20 70.3 7.7 1.4 1 0 0 1 1 1 1 Homeodomain SR-25 PF10500.9 KFP01197.1 - 0.01 15.4 4.7 0.015 14.9 4.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Homeobox_KN PF05920.11 KFP01197.1 - 0.044 13.7 0.8 0.088 12.7 0.8 1.5 1 0 0 1 1 1 0 Homeobox KN domain Homeodomain PF00046.29 KFP01198.1 - 1.9e-19 69.3 8.0 2.2e-19 69.0 8.0 1.1 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP01198.1 - 5.8e-05 22.9 2.5 8.4e-05 22.4 2.5 1.4 1 1 0 1 1 1 1 Homeobox KN domain DUF1510 PF07423.11 KFP01198.1 - 0.036 14.2 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1510) CI-B14_5a PF07347.12 KFP01198.1 - 0.037 13.9 0.8 0.042 13.7 0.2 1.4 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Homez PF11569.8 KFP01198.1 - 0.096 12.2 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Homeodomain PF00046.29 KFP01199.1 - 3.5e-21 74.8 4.9 5.7e-21 74.1 4.9 1.3 1 0 0 1 1 1 1 Homeodomain NAD_binding_2 PF03446.15 KFP01200.1 - 5.2e-50 169.7 0.2 7.4e-50 169.2 0.2 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFP01200.1 - 1.4e-33 115.7 0.0 2.2e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 KFP01200.1 - 2.5e-09 36.7 0.0 4.4e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KFP01200.1 - 3.3e-07 30.8 0.0 9.6e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KFP01200.1 - 0.00029 20.8 0.0 0.00065 19.6 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PDH PF02153.17 KFP01200.1 - 0.0045 16.0 0.0 0.006 15.6 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase DpaA_N PF16924.5 KFP01200.1 - 0.014 15.5 0.0 0.099 12.7 0.0 2.3 2 0 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain IlvN PF07991.12 KFP01200.1 - 0.025 14.2 0.1 0.047 13.3 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KFP01200.1 - 0.026 14.8 0.1 0.098 12.9 0.0 2.1 2 1 0 2 2 2 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KFP01200.1 - 0.1 12.2 0.0 3.3 7.2 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-C2H2_aberr PF17017.5 KFP01201.1 - 8.6e-07 29.3 2.7 6.2e-05 23.2 0.2 2.2 1 1 1 2 2 2 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 KFP01201.1 - 0.0017 19.1 6.3 0.54 11.3 2.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP01201.1 - 0.012 16.0 6.8 0.68 10.5 2.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 KFP01201.1 - 0.16 11.6 0.1 0.75 9.5 0.0 2.0 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain ARS2 PF04959.13 KFP01201.1 - 0.21 12.0 4.5 9.5 6.5 0.4 2.8 1 1 2 3 3 3 0 Arsenite-resistance protein 2 bZIP_1 PF00170.21 KFP01202.1 - 7.2e-13 48.4 8.5 1.3e-12 47.6 8.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFP01202.1 - 3.3e-10 39.9 7.9 3.3e-10 39.9 7.9 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFP01202.1 - 4.1e-05 24.0 5.1 0.00013 22.4 5.1 1.8 1 0 0 1 1 1 1 bZIP Maf transcription factor ZapB PF06005.12 KFP01202.1 - 0.0089 16.4 2.7 0.0089 16.4 2.7 1.7 2 0 0 2 2 2 1 Cell division protein ZapB TolA_bind_tri PF16331.5 KFP01202.1 - 0.022 14.8 3.1 0.022 14.8 3.1 2.5 3 0 0 3 3 3 0 TolA binding protein trimerisation NDUFB11 PF17250.2 KFP01202.1 - 0.13 12.9 2.5 0.12 13.0 0.9 1.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase 11 kDa subunit GIT_CC PF16559.5 KFP01202.1 - 0.15 11.9 5.0 0.45 10.4 5.0 1.8 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.15 KFP01202.1 - 0.46 10.3 3.1 0.91 9.3 3.1 1.4 1 0 0 1 1 1 0 Septum formation initiator Zip PF02535.22 KFP01202.1 - 1.6 7.9 10.7 2.5 7.2 10.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Cnn_1N PF07989.11 KFP01202.1 - 3.2 8.0 7.6 0.24 11.6 2.5 1.8 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 RhoGAP PF00620.27 KFP01203.1 - 2.8e-50 170.1 0.0 6.1e-50 169.0 0.0 1.5 2 0 0 2 2 2 1 RhoGAP domain C1_1 PF00130.22 KFP01203.1 - 1.5e-16 60.0 7.0 2.6e-16 59.3 7.0 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH2 PF00017.24 KFP01203.1 - 5.6e-12 45.6 0.1 2e-11 43.8 0.0 2.0 2 0 0 2 2 2 1 SH2 domain zf-RING-like PF08746.11 KFP01203.1 - 0.058 13.7 5.0 0.14 12.5 5.0 1.6 1 0 0 1 1 1 0 RING-like domain PHD_2 PF13831.6 KFP01203.1 - 0.12 12.0 2.3 0.26 10.9 2.3 1.5 1 0 0 1 1 1 0 PHD-finger C1_2 PF03107.16 KFP01203.1 - 0.21 11.9 3.0 0.54 10.6 3.0 1.7 1 0 0 1 1 1 0 C1 domain FYVE_2 PF02318.16 KFP01203.1 - 1.9 8.7 9.2 1.6 9.0 7.1 2.0 1 1 1 2 2 2 0 FYVE-type zinc finger PHD PF00628.29 KFP01203.1 - 6.8 6.7 9.1 15 5.6 9.1 1.5 1 0 0 1 1 1 0 PHD-finger WH2 PF02205.20 KFP01204.1 - 9.6e-10 38.0 0.9 1.8e-09 37.1 0.9 1.5 1 0 0 1 1 1 1 WH2 motif Peptidase_C69 PF03577.15 KFP01205.1 - 6.4e-09 35.2 0.0 1e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C69 AAT PF03417.16 KFP01205.1 - 0.03 14.0 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase FKBP_C PF00254.28 KFP01206.1 - 1.6e-28 98.9 0.0 2.6e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_7 PF13499.6 KFP01206.1 - 3.2e-07 30.7 3.0 5.8e-07 29.9 3.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP01206.1 - 3.9e-06 26.4 3.2 0.034 14.1 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFP01206.1 - 2.2e-05 23.7 2.4 0.057 12.9 1.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 KFP01206.1 - 0.00028 20.2 7.8 0.011 15.3 1.4 2.8 3 0 0 3 3 3 2 EF hand Collagen PF01391.18 KFP01207.1 - 2.5e-28 97.6 94.4 1e-09 38.0 22.0 4.4 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) DUF4215 PF13948.6 KFP01207.1 - 2.8e-05 24.5 12.8 6.5e-05 23.3 6.2 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4215) CAP_N PF01213.19 KFP01207.1 - 0.19 11.2 0.4 0.36 10.3 0.4 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TPP_enzyme_M PF00205.22 KFP01208.1 - 2.5e-35 121.2 0.0 8.3e-35 119.5 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.18 KFP01208.1 - 3e-30 105.1 0.0 1.9e-28 99.2 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KFP01208.1 - 1.2e-27 96.5 0.0 2.9e-27 95.3 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Ank_2 PF12796.7 KFP01209.1 - 2e-164 534.6 67.6 7.5e-18 64.9 0.2 14.0 3 3 14 17 17 17 17 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP01209.1 - 4.3e-154 499.1 47.0 8.6e-15 54.9 0.8 20.7 7 3 15 22 22 22 22 Ankyrin repeats (many copies) Ank PF00023.30 KFP01209.1 - 4.4e-143 460.1 74.8 6.6e-07 29.5 0.1 28.0 28 0 0 28 28 28 26 Ankyrin repeat Ank_3 PF13606.6 KFP01209.1 - 9.6e-119 372.8 51.5 6.5e-06 26.1 0.1 28.1 28 0 0 28 28 28 27 Ankyrin repeat Ank_5 PF13857.6 KFP01209.1 - 2.2e-118 384.7 57.5 9.8e-10 38.5 0.1 21.3 5 4 19 24 24 24 22 Ankyrin repeats (many copies) RVT_1 PF00078.27 KFP01210.1 - 0.0017 17.9 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glycos_transf_2 PF00535.26 KFP01211.1 - 1.7e-29 102.8 0.0 2.9e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFP01211.1 - 1.7e-18 67.1 0.8 3e-18 66.3 0.8 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 KFP01211.1 - 1.2e-05 25.3 0.0 2.4e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KFP01211.1 - 9e-05 22.1 0.0 0.00053 19.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KFP01211.1 - 0.00011 21.8 0.0 0.00024 20.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.6 KFP01211.1 - 0.00012 22.8 0.0 0.00079 20.1 0.0 2.2 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Hydrolase_6 PF13344.6 KFP01212.1 - 6.2e-09 35.9 0.0 6.5e-09 35.8 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Yos1 PF08571.10 KFP01213.1 - 3.2e-30 104.2 0.4 3.5e-30 104.1 0.4 1.0 1 0 0 1 1 1 1 Yos1-like UL45 PF05473.12 KFP01214.1 - 0.0022 17.7 1.7 0.0023 17.6 1.0 1.4 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like PigN PF04987.14 KFP01214.1 - 0.032 13.1 0.5 0.04 12.8 0.5 1.0 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) Chordopox_A33R PF05966.12 KFP01214.1 - 0.035 13.4 0.1 0.06 12.6 0.1 1.4 1 0 0 1 1 1 0 Chordopoxvirus A33R protein YqzM PF14141.6 KFP01214.1 - 4.3 7.5 6.0 14 5.8 1.9 2.4 2 0 0 2 2 2 0 YqzM-like protein RabGAP-TBC PF00566.18 KFP01215.1 - 5e-19 68.8 3.2 3.6e-15 56.2 0.2 2.5 2 1 1 3 3 3 2 Rab-GTPase-TBC domain 7tm_4 PF13853.6 KFP01216.1 - 7.6e-50 170.2 26.2 8.7e-50 170.0 26.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP01216.1 - 1.8e-28 99.6 23.2 2.5e-28 99.1 23.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP01216.1 - 0.042 13.2 27.3 0.68 9.3 27.3 2.2 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx EF-hand_7 PF13499.6 KFP01217.1 - 4.5e-17 62.2 15.2 5.6e-07 29.9 0.9 3.5 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 KFP01217.1 - 1.8e-16 58.4 16.0 2e-05 23.8 0.2 5.3 5 1 1 6 6 6 4 EF hand EF-hand_6 PF13405.6 KFP01217.1 - 2.2e-13 49.0 11.5 0.0014 18.4 0.1 4.8 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 KFP01217.1 - 5.5e-13 47.8 7.7 0.0022 17.4 0.3 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KFP01217.1 - 5.2e-08 32.6 11.5 0.023 14.5 0.3 5.0 4 1 1 5 5 5 3 EF-hand domain pair BCNT PF07572.12 KFP01217.1 - 0.12 12.4 0.3 0.12 12.4 0.3 2.6 3 1 0 3 3 3 0 Bucentaur or craniofacial development SPARC_Ca_bdg PF10591.9 KFP01217.1 - 0.71 10.2 12.2 2.1 8.7 0.5 3.5 2 2 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SCAPER_N PF16501.5 KFP01218.1 - 3.6e-44 148.8 0.3 3.6e-44 148.8 0.3 2.8 2 0 0 2 2 2 1 S phase cyclin A-associated protein in the endoplasmic reticulum zf-met PF12874.7 KFP01218.1 - 6.5e-07 29.5 1.7 2.1e-06 27.9 1.7 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP01218.1 - 0.01 16.1 0.9 0.034 14.4 0.9 2.0 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF5487 PF17589.2 KFP01218.1 - 0.18 12.1 0.1 0.4 11.0 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5487) ETF PF01012.21 KFP01219.1 - 8.5e-42 143.1 0.2 1.2e-41 142.6 0.2 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KFP01219.1 - 1.1e-37 128.0 1.3 1.4e-37 127.6 0.2 1.7 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain Ion_trans PF00520.31 KFP01220.1 - 2.5e-07 30.2 7.0 3.6e-07 29.7 7.0 1.1 1 0 0 1 1 1 1 Ion transport protein zf-C4H2 PF10146.9 KFP01220.1 - 0.047 14.0 1.9 0.083 13.2 1.9 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein EGF PF00008.27 KFP01221.1 - 0.00068 19.9 5.9 0.00097 19.4 5.9 1.3 1 0 0 1 1 1 1 EGF-like domain EGF_2 PF07974.13 KFP01221.1 - 0.0035 17.7 3.6 0.009 16.4 3.6 1.7 1 1 0 1 1 1 1 EGF-like domain Laminin_EGF PF00053.24 KFP01221.1 - 0.047 13.8 1.3 0.068 13.3 1.3 1.3 1 1 0 1 1 1 0 Laminin EGF domain hEGF PF12661.7 KFP01221.1 - 0.31 11.7 4.5 1.4 9.7 2.5 2.8 2 1 0 2 2 2 0 Human growth factor-like EGF FIST_C PF10442.9 KFP01222.1 - 1.8e-12 47.3 0.0 4.3e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 FIST C domain FIST PF08495.10 KFP01222.1 - 2.7e-05 24.2 0.0 0.012 15.6 0.0 2.1 2 0 0 2 2 2 2 FIST N domain Toprim_3 PF13362.6 KFP01222.1 - 0.038 14.4 0.0 0.098 13.0 0.0 1.7 1 0 0 1 1 1 0 Toprim domain UQ_con PF00179.26 KFP01223.1 - 6.5e-11 42.1 0.0 7.1e-10 38.7 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFP01223.1 - 0.0059 16.3 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B TraC_F_IV PF11130.8 KFP01223.1 - 0.035 13.7 0.0 5.6 6.5 0.0 2.2 2 0 0 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer KIAA1430 PF13879.6 KFP01223.1 - 0.04 14.7 2.2 2.2 9.1 0.1 2.9 3 0 0 3 3 3 0 KIAA1430 homologue Josephin PF02099.17 KFP01223.1 - 0.047 13.8 0.0 0.064 13.4 0.0 1.5 1 0 0 1 1 1 0 Josephin TPR_MLP1_2 PF07926.12 KFP01223.1 - 0.6 10.2 4.2 0.61 10.1 0.5 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Neur_chan_memb PF02932.16 KFP01224.1 - 2.9e-80 269.8 16.7 3.1e-56 191.1 14.6 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFP01224.1 - 1.2e-70 237.3 1.3 1.8e-70 236.7 1.3 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF2417 PF10329.9 KFP01224.1 - 0.0083 15.6 4.6 0.017 14.6 3.6 1.9 2 0 0 2 2 2 1 Region of unknown function (DUF2417) Neur_chan_memb PF02932.16 KFP01225.1 - 4.6e-86 288.8 13.4 1.2e-63 215.3 10.3 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFP01225.1 - 1.2e-74 250.4 1.3 2.1e-74 249.6 1.3 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain FtsK_alpha PF17854.1 KFP01225.1 - 0.066 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 FtsK alpha domain Neur_chan_LBD PF02931.23 KFP01226.1 - 4.7e-73 245.2 0.6 6.2e-73 244.8 0.6 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP01226.1 - 8.5e-66 222.4 13.6 2.1e-50 172.0 10.2 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Proteasome PF00227.26 KFP01227.1 - 5.2e-49 166.3 0.0 7.4e-49 165.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFP01227.1 - 8e-14 51.0 0.1 1.4e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Phenol_monoox PF04663.12 KFP01227.1 - 0.12 12.5 0.1 0.27 11.4 0.1 1.5 1 0 0 1 1 1 0 Phenol hydroxylase conserved region APH PF01636.23 KFP01228.1 - 2.2e-22 80.2 0.0 2.9e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFP01228.1 - 0.0062 15.9 0.0 0.0085 15.4 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Kdo PF06293.14 KFP01228.1 - 0.11 11.9 0.1 0.23 10.8 0.1 1.6 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aconitase PF00330.20 KFP01229.1 - 1.8e-155 518.5 0.0 2.3e-155 518.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KFP01229.1 - 2.1e-40 138.1 0.0 3.6e-40 137.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Actin PF00022.19 KFP01230.1 - 1.7e-82 277.2 0.0 1.2e-48 165.7 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 KFP01230.1 - 0.00014 20.8 0.0 0.23 10.2 0.0 2.3 2 1 0 2 2 2 2 MreB/Mbl protein EamA PF00892.20 KFP01231.1 - 4.1e-11 43.2 40.5 1.9e-06 28.1 5.0 3.2 3 0 0 3 3 3 3 EamA-like transporter family PUNUT PF16913.5 KFP01231.1 - 9e-07 28.4 3.2 9e-07 28.4 3.2 2.2 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport MHYT PF03707.16 KFP01231.1 - 0.75 10.0 5.9 0.98 9.6 0.0 3.3 3 1 0 3 3 3 0 Bacterial signalling protein N terminal repeat 7tm_1 PF00001.21 KFP01232.1 - 1.5e-33 116.2 8.0 1.9e-33 115.9 7.2 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP01232.1 - 0.00033 20.5 3.8 0.067 12.9 0.8 2.5 2 0 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srv PF10323.9 KFP01232.1 - 0.0016 17.9 10.8 0.016 14.6 0.6 2.3 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 KFP01232.1 - 0.0023 17.6 2.1 0.0023 17.6 2.1 2.3 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx UPAR_LY6_2 PF16975.5 KFP01233.1 - 0.00077 19.6 9.8 0.001 19.2 9.8 1.1 1 0 0 1 1 1 1 Ly6/PLAUR domain-containing protein 6, Lypd6 NCKAP5 PF15246.6 KFP01234.1 - 3.2e-123 411.3 22.1 3.2e-123 411.3 22.1 5.6 5 1 1 6 6 6 1 Nck-associated protein 5, Peripheral clock protein Mei4 PF13971.6 KFP01235.1 - 0.37 10.2 4.2 0.49 9.8 4.2 1.2 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 FTO_CTD PF12934.7 KFP01235.1 - 0.81 9.4 7.2 8.6 6.1 0.0 2.0 1 1 1 2 2 2 0 FTO C-terminal domain 5_nucleotid PF05761.14 KFP01235.1 - 0.96 8.3 4.7 1.1 8.0 4.7 1.1 1 0 0 1 1 1 0 5' nucleotidase family Spc29 PF17082.5 KFP01235.1 - 1.6 8.5 7.3 8.4 6.1 1.3 2.1 1 1 1 2 2 2 0 Spindle Pole Component 29 Glyco_transf_18 PF15024.6 KFP01236.1 - 2.2e-265 881.6 0.7 2.7e-265 881.3 0.7 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 18 DUF4525 PF15027.6 KFP01236.1 - 4.1e-64 214.4 0.1 7.1e-64 213.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4525) Cation_efflux PF01545.21 KFP01237.1 - 0.00033 20.5 2.3 0.00033 20.5 2.3 3.5 2 2 1 3 3 3 2 Cation efflux family DUF2157 PF09925.9 KFP01237.1 - 3.7 7.3 9.6 21 4.9 9.6 2.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF308 PF03729.13 KFP01237.1 - 3.7 8.0 19.5 6.1 7.3 6.6 3.3 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) Yae1_N PF09811.9 KFP01238.1 - 3.6e-12 45.8 39.3 1.8e+04 -4.6 39.3 4.2 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Amidohydro_2 PF04909.14 KFP01239.1 - 9.5e-65 219.2 0.0 1.1e-64 219.1 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Cyclin_N PF00134.23 KFP01240.1 - 1e-15 57.6 1.6 1.5e-12 47.4 0.2 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Pkinase PF00069.25 KFP01241.1 - 3.7e-55 187.1 0.0 4.2e-55 186.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP01241.1 - 8.9e-38 130.0 0.0 1e-37 129.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP01241.1 - 1.4e-05 24.5 0.0 3.2e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KFP01241.1 - 0.0012 18.8 0.1 0.0031 17.5 0.1 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFP01241.1 - 0.0014 17.5 0.0 0.0017 17.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 KFP01241.1 - 0.091 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Rab3-GTPase_cat PF13890.6 KFP01242.1 - 7e-67 224.1 0.0 3.5e-66 221.9 0.0 2.2 3 0 0 3 3 3 1 Rab3 GTPase-activating protein catalytic subunit R3H PF01424.22 KFP01243.1 - 3.8e-12 46.0 0.0 1e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 R3H domain SUZ PF12752.7 KFP01243.1 - 8.2e-12 45.7 6.4 8.2e-12 45.7 6.4 4.9 5 0 0 5 5 5 1 SUZ domain UBX PF00789.20 KFP01244.1 - 8.9e-19 67.5 0.0 2e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 UBX domain tRNA-synt_2 PF00152.20 KFP01245.1 - 1.4e-77 260.9 0.1 1.8e-77 260.5 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFP01245.1 - 9e-10 38.4 0.9 1.7e-09 37.6 0.9 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KFP01245.1 - 0.00012 21.7 0.2 0.54 9.7 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) S-AdoMet_synt_N PF00438.20 KFP01245.1 - 0.016 15.9 0.3 0.1 13.3 0.2 2.2 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, N-terminal domain tRNA_anti_2 PF13742.6 KFP01245.1 - 0.031 14.5 0.1 0.075 13.2 0.1 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain 7tm_1 PF00001.21 KFP01246.1 - 1e-50 172.5 14.3 1.3e-50 172.2 14.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CXCR4_N PF12109.8 KFP01246.1 - 4.5e-19 68.3 6.8 8.1e-19 67.5 6.8 1.4 1 0 0 1 1 1 1 CXCR4 Chemokine receptor N terminal 7TM_GPCR_Srsx PF10320.9 KFP01246.1 - 0.0008 18.9 12.4 0.0012 18.3 12.1 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx COX2_TM PF02790.15 KFP01246.1 - 0.26 11.5 0.1 0.26 11.5 0.1 2.7 3 1 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain TctB PF07331.11 KFP01246.1 - 0.54 10.5 11.3 0.21 11.9 2.6 2.5 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family Methyltransf_23 PF13489.6 KFP01247.1 - 2.7e-14 53.3 0.0 5.6e-14 52.3 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP01247.1 - 3.6e-07 30.8 0.0 6.8e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP01247.1 - 0.0031 17.3 0.0 0.0065 16.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KFP01247.1 - 0.0044 16.7 0.0 0.0069 16.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) DsrC PF04358.13 KFP01247.1 - 0.016 15.7 1.0 0.032 14.8 1.0 1.4 1 0 0 1 1 1 0 DsrC like protein DUF5099 PF17025.5 KFP01247.1 - 0.096 13.1 0.1 0.25 11.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5099) Methyltransf_25 PF13649.6 KFP01247.1 - 0.12 13.0 0.0 0.26 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain WIF PF02019.18 KFP01247.1 - 0.16 11.7 0.6 0.48 10.1 0.2 2.0 2 0 0 2 2 2 0 WIF domain RVT_1 PF00078.27 KFP01248.1 - 0.0055 16.3 0.0 0.0087 15.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BTB PF00651.31 KFP01250.1 - 2.4e-34 117.9 0.6 1.4e-33 115.4 0.1 2.1 1 1 1 2 2 2 1 BTB/POZ domain MATH PF00917.26 KFP01250.1 - 1.4e-06 28.4 0.0 2.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 MATH domain Neurexophilin PF06312.12 KFP01251.1 - 1.9e-97 324.9 4.7 2.3e-97 324.6 4.7 1.0 1 0 0 1 1 1 1 Neurexophilin Nepo_coat_C PF03688.14 KFP01251.1 - 0.077 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Nepovirus coat protein, C-terminal domain EGF_2 PF07974.13 KFP01252.1 - 6.8e-20 71.1 58.5 7.3e-06 26.3 6.2 4.2 3 1 1 4 4 4 4 EGF-like domain EGF PF00008.27 KFP01252.1 - 4.1e-14 52.6 59.9 0.00053 20.2 9.3 4.7 4 0 0 4 4 4 4 EGF-like domain hEGF PF12661.7 KFP01252.1 - 2.6e-06 27.9 64.5 0.0054 17.3 7.6 6.0 7 0 0 7 7 7 4 Human growth factor-like EGF Laminin_EGF PF00053.24 KFP01252.1 - 0.089 12.9 54.2 2.5 8.3 7.0 4.2 1 1 3 4 4 4 0 Laminin EGF domain Metallothio PF00131.20 KFP01252.1 - 5.7 7.1 50.6 12 6.1 23.0 3.4 1 1 2 3 3 3 0 Metallothionein EGF PF00008.27 KFP01253.1 - 7.1e-08 32.6 23.6 1e-05 25.7 6.4 4.6 4 0 0 4 4 4 2 EGF-like domain hEGF PF12661.7 KFP01253.1 - 8.9e-05 23.0 17.7 0.00034 21.1 7.5 5.3 4 2 0 4 4 4 2 Human growth factor-like EGF HDV_ag PF01517.18 KFP01254.1 - 0.048 13.4 0.2 0.055 13.2 0.2 1.0 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen VWD PF00094.25 KFP01255.1 - 0.0026 18.1 0.2 0.0046 17.2 0.2 1.5 1 0 0 1 1 1 1 von Willebrand factor type D domain TMEM154 PF15102.6 KFP01256.1 - 0.00094 19.1 0.0 0.00094 19.1 0.0 1.1 1 0 0 1 1 1 1 TMEM154 protein family DUF3377 PF11857.8 KFP01256.1 - 0.0024 17.8 0.2 0.0032 17.3 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) DUF1560 PF07597.11 KFP01256.1 - 0.0075 16.3 0.1 0.012 15.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1560) DUF4448 PF14610.6 KFP01256.1 - 0.013 15.3 0.0 0.016 15.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF5527 PF17665.1 KFP01256.1 - 0.019 14.5 0.0 0.023 14.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Adeno_E3_CR2 PF02439.15 KFP01256.1 - 0.09 12.6 1.1 0.13 12.0 1.1 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 MLANA PF14991.6 KFP01256.1 - 0.12 12.6 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein melan-A Ldl_recept_b PF00058.17 KFP01257.1 - 2.2e-29 101.7 5.5 4.7e-11 43.0 0.0 4.1 4 0 0 4 4 4 3 Low-density lipoprotein receptor repeat class B SGL PF08450.12 KFP01257.1 - 1.2e-05 25.0 0.0 5.2e-05 22.9 0.0 1.8 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region DUF5050 PF16472.5 KFP01257.1 - 0.011 15.0 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5050) Arylesterase PF01731.20 KFP01257.1 - 0.1 12.8 0.0 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 Arylesterase Ldl_recept_b PF00058.17 KFP01258.1 - 4e-13 49.6 0.1 2.9e-05 24.4 0.0 2.6 3 0 0 3 3 3 2 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 KFP01258.1 - 2e-08 34.4 5.7 4.3e-08 33.3 5.6 1.7 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFP01258.1 - 0.00053 19.9 2.0 0.0011 18.9 2.0 1.5 1 0 0 1 1 1 1 Complement Clr-like EGF-like SGL PF08450.12 KFP01258.1 - 0.11 12.0 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Aminotran_5 PF00266.19 KFP01259.1 - 6.6e-15 54.9 0.0 8.8e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V RhoGAP PF00620.27 KFP01260.1 - 1.4e-52 177.6 1.3 1.1e-51 174.7 0.0 2.3 3 0 0 3 3 3 1 RhoGAP domain RPEL PF02755.15 KFP01260.1 - 0.025 14.3 0.5 0.077 12.7 0.5 1.9 1 0 0 1 1 1 0 RPEL repeat CLTH PF10607.9 KFP01260.1 - 0.069 13.0 0.3 0.11 12.3 0.1 1.6 2 0 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain DUF3524 PF12038.8 KFP01261.1 - 4.4e-73 244.6 0.2 7.3e-73 243.9 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3524) Glycos_transf_1 PF00534.20 KFP01261.1 - 3.5e-06 26.7 0.0 7.2e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 zf-H2C2_2 PF13465.6 KFP01262.1 - 1.3e-32 110.7 61.1 1.2e-07 31.8 5.1 8.7 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFP01262.1 - 3.2e-25 87.1 72.8 0.00012 22.4 5.0 8.7 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP01262.1 - 5.4e-16 57.9 69.3 0.0049 17.6 1.0 8.8 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP01262.1 - 2.8e-08 33.8 56.5 0.01 16.1 1.9 9.1 9 0 0 9 9 9 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFP01262.1 - 3e-08 33.8 1.9 3e-08 33.8 1.9 4.3 4 0 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KFP01262.1 - 3.7e-08 33.5 54.5 0.0087 16.4 0.4 8.4 8 0 0 8 8 8 4 Zinc-finger of C2H2 type Homeodomain PF00046.29 KFP01262.1 - 0.00012 21.8 0.0 0.00072 19.4 0.0 2.4 2 0 0 2 2 2 1 Homeodomain zf-H2C2_5 PF13909.6 KFP01262.1 - 0.0019 17.9 0.4 0.0019 17.9 0.4 6.1 6 1 0 6 6 4 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFP01262.1 - 0.018 15.0 68.2 0.029 14.4 1.5 8.5 8 0 0 8 8 8 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFP01262.1 - 0.02 15.2 1.1 0.02 15.2 1.1 7.2 4 3 3 7 7 7 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KFP01262.1 - 2.7 7.8 33.6 0.11 12.3 0.5 6.7 7 0 0 7 7 7 0 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 KFP01262.1 - 3.1 8.6 29.5 0.33 11.7 1.5 5.2 4 1 1 5 5 5 0 zinc-ribbon family zf-RING_7 PF02591.15 KFP01262.1 - 3.9 7.8 8.8 9.2 6.5 0.0 4.2 4 0 0 4 4 4 0 C4-type zinc ribbon domain Actin_micro PF17003.5 KFP01262.1 - 5.9 6.0 18.2 3.4 6.8 2.9 4.3 2 2 2 4 4 4 0 Putative actin-like family Ig_3 PF13927.6 KFP01263.1 - 5.4e-30 103.8 10.8 1.4e-14 54.4 0.4 4.4 4 0 0 4 4 4 4 Immunoglobulin domain I-set PF07679.16 KFP01263.1 - 6.7e-26 90.2 4.6 8.4e-10 38.6 0.1 4.7 4 1 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP01263.1 - 4.5e-22 78.2 2.7 1.6e-12 47.6 0.1 4.2 4 0 0 4 4 4 2 Immunoglobulin domain ig PF00047.25 KFP01263.1 - 5.9e-15 55.2 1.7 1.2e-06 28.6 0.2 4.3 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 KFP01263.1 - 5.5e-13 49.1 2.7 0.0036 17.5 0.0 5.0 4 1 1 5 5 5 4 Immunoglobulin V-set domain Ig_4 PF16680.5 KFP01263.1 - 2.5e-08 34.1 0.1 0.00037 20.7 0.0 4.2 4 0 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFP01263.1 - 7.4e-07 29.5 1.9 0.00084 19.7 0.0 3.7 3 1 1 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KFP01263.1 - 0.00044 20.3 0.5 0.13 12.3 0.0 2.7 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain MLANA PF14991.6 KFP01263.1 - 0.031 14.5 0.0 0.062 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A Lep_receptor_Ig PF06328.11 KFP01263.1 - 0.11 12.5 0.2 4.7 7.2 0.0 2.7 3 0 0 3 3 3 0 Ig-like C2-type domain Endosulfine PF04667.17 KFP01266.1 - 5.7e-09 36.0 4.3 8.7e-09 35.4 4.3 1.3 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Ntox30 PF15532.6 KFP01266.1 - 0.057 13.8 0.0 0.064 13.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin 30 GPP34 PF05719.11 KFP01267.1 - 2.1e-40 139.0 3.0 2.3e-39 135.6 3.0 2.0 1 1 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) HORMA PF02301.18 KFP01268.1 - 3.6e-49 167.2 0.0 5.1e-26 91.6 0.0 2.2 1 1 1 2 2 2 2 HORMA domain DUF2756 PF10956.8 KFP01270.1 - 0.12 12.9 2.6 0.93 10.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2756) C2 PF00168.30 KFP01271.1 - 1.6e-45 153.6 0.1 2.2e-21 76.1 0.0 2.4 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 KFP01271.1 - 0.00027 20.5 0.0 0.099 12.2 0.0 2.7 2 1 0 2 2 2 2 CEP76 C2 domain PTEN_C2 PF10409.9 KFP01271.1 - 0.066 13.0 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein CoatB PF10389.9 KFP01271.1 - 0.33 10.8 4.0 0.75 9.7 4.0 1.6 1 0 0 1 1 1 0 Bacteriophage coat protein B YjeF_N PF03853.15 KFP01272.1 - 8.8e-33 113.6 0.0 1e-32 113.4 0.0 1.0 1 0 0 1 1 1 1 YjeF-related protein N-terminus RasGAP PF00616.19 KFP01273.1 - 1.5e-53 181.6 0.0 3.3e-53 180.5 0.0 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KFP01273.1 - 2.4e-33 115.2 10.3 2.4e-33 115.2 10.3 2.7 3 0 0 3 3 3 1 RasGAP C-terminus IQ PF00612.27 KFP01273.1 - 3.2e-19 66.9 15.0 2.4e-06 26.8 1.0 5.2 4 0 0 4 4 4 4 IQ calmodulin-binding motif CH PF00307.31 KFP01273.1 - 1e-16 61.1 0.1 1.6e-15 57.2 0.0 2.8 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFP01273.1 - 0.021 14.7 0.0 0.063 13.1 0.0 1.8 1 0 0 1 1 1 0 CAMSAP CH domain SHD1 PF03983.12 KFP01273.1 - 0.072 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 SLA1 homology domain 1, SHD1 FTA4 PF13093.6 KFP01273.1 - 0.68 9.8 15.1 0.18 11.6 2.2 3.9 3 1 1 4 4 4 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 SRF-TF PF00319.18 KFP01276.1 - 6.8e-20 70.3 0.4 1.1e-19 69.6 0.4 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C PF12347.8 KFP01276.1 - 5.7e-12 45.5 0.0 2.3e-11 43.6 0.0 2.1 1 0 0 1 1 1 1 Holliday junction regulator protein family C-terminal repeat zf-H2C2_2 PF13465.6 KFP01277.1 - 2.9e-13 49.6 7.9 2.1e-06 27.9 0.3 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFP01277.1 - 6.5e-10 38.9 11.4 6.3e-05 23.2 1.2 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFP01277.1 - 1.1e-06 28.5 1.8 1.7e-06 27.8 0.2 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KFP01277.1 - 1.5e-05 25.4 12.5 0.00058 20.5 0.6 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP01277.1 - 0.00024 21.3 0.2 0.0027 17.9 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP01277.1 - 0.00069 19.9 2.0 0.0014 19.0 0.2 2.5 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFP01277.1 - 0.05 13.9 2.5 0.16 12.3 2.6 1.8 1 1 0 1 1 1 0 C2H2-type zinc ribbon UNC119_bdg PF15435.6 KFP01278.1 - 4.8e-92 307.0 1.2 5.3e-92 306.8 1.2 1.0 1 0 0 1 1 1 1 UNC119-binding protein C5orf30 homologue Filament PF00038.21 KFP01280.1 - 1.1e-112 376.6 21.6 1.3e-112 376.4 21.6 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFP01280.1 - 3.6e-30 105.2 32.3 5e-30 104.8 32.3 1.2 1 0 0 1 1 1 1 Keratin type II head TPR_MLP1_2 PF07926.12 KFP01280.1 - 1.2e-05 25.3 26.6 0.0016 18.5 0.8 4.0 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 KFP01280.1 - 2.3e-05 24.7 16.2 0.005 17.1 7.1 2.6 1 1 0 2 2 2 2 Autophagy protein 16 (ATG16) AAA_13 PF13166.6 KFP01280.1 - 0.00031 19.5 10.6 0.00031 19.5 10.6 1.9 2 1 0 2 2 2 1 AAA domain Tropomyosin_1 PF12718.7 KFP01280.1 - 0.00093 19.4 25.3 0.0015 18.7 6.4 3.7 3 1 0 3 3 3 1 Tropomyosin like BRE1 PF08647.11 KFP01280.1 - 0.0069 16.4 23.9 0.011 15.8 2.8 4.5 3 1 1 4 4 4 1 BRE1 E3 ubiquitin ligase Golgin_A5 PF09787.9 KFP01280.1 - 0.022 14.3 23.3 0.078 12.4 5.5 3.1 2 1 0 3 3 3 0 Golgin subfamily A member 5 T7SS_ESX_EspC PF10824.8 KFP01280.1 - 0.025 15.0 0.1 1.7 9.1 0.3 2.8 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm DUF4407 PF14362.6 KFP01280.1 - 0.034 13.5 14.5 1.6e+02 1.5 14.4 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SPATA1_C PF15743.5 KFP01280.1 - 0.039 14.0 0.2 0.039 14.0 0.2 3.6 3 1 0 3 3 3 0 Spermatogenesis-associated C-terminus Spc7 PF08317.11 KFP01280.1 - 0.044 12.7 28.5 0.12 11.2 7.4 3.5 2 1 1 3 3 3 0 Spc7 kinetochore protein mRNA_decap_C PF16741.5 KFP01280.1 - 0.056 12.8 0.0 1.9 7.9 0.0 2.5 2 0 0 2 2 2 0 mRNA-decapping enzyme C-terminus DUF4494 PF14902.6 KFP01280.1 - 0.082 12.7 0.4 0.082 12.7 0.4 2.4 3 0 0 3 3 2 0 Domain of unknown function (DUF4494) Jnk-SapK_ap_N PF09744.9 KFP01280.1 - 0.12 12.6 23.8 0.3 11.3 3.4 3.7 2 1 2 4 4 4 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 KFP01280.1 - 0.16 12.0 19.3 1.3 9.0 1.3 4.7 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 KFP01280.1 - 0.38 11.2 15.0 0.28 11.7 1.5 4.4 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein GAS PF13851.6 KFP01280.1 - 0.49 9.7 27.9 0.17 11.2 5.7 3.7 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.12 KFP01280.1 - 0.54 10.3 11.5 0.68 10.0 1.9 4.1 2 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus PP_kinase_N PF13089.6 KFP01280.1 - 0.64 10.4 0.0 0.64 10.4 0.0 3.6 3 1 2 5 5 5 0 Polyphosphate kinase N-terminal domain CHDCT2 PF08074.11 KFP01280.1 - 0.88 9.7 11.8 0.43 10.8 0.4 3.2 2 1 0 3 3 3 0 CHDCT2 (NUC038) domain DUF4509 PF14970.6 KFP01280.1 - 1.2 9.0 6.6 0.13 12.2 0.5 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4509) CENP-F_leu_zip PF10473.9 KFP01280.1 - 1.3 9.0 26.1 2.5 8.1 5.8 4.0 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V_ATPase_I PF01496.19 KFP01280.1 - 1.4 6.7 13.6 4.4 5.1 13.6 1.8 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 KFP01280.1 - 1.5 8.9 23.9 6.8 6.8 7.0 3.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus SPT16 PF08644.11 KFP01280.1 - 2 8.6 10.0 12 6.0 0.6 3.3 2 1 1 3 3 3 0 FACT complex subunit (SPT16/CDC68) Rho_Binding PF08912.11 KFP01280.1 - 2 9.3 29.8 0.9 10.4 1.9 6.0 4 1 2 6 6 5 0 Rho Binding Phage_GP20 PF06810.11 KFP01280.1 - 2.3 8.0 20.6 0.27 11.0 5.0 3.5 3 1 0 3 3 3 0 Phage minor structural protein GP20 Virulence_fact PF13769.6 KFP01280.1 - 2.3 8.5 5.4 0.63 10.3 0.3 2.6 3 0 0 3 3 1 0 Virulence factor SlyX PF04102.12 KFP01280.1 - 2.4 8.8 17.9 0.42 11.3 0.3 4.6 4 1 1 5 5 4 0 SlyX Tup_N PF08581.10 KFP01280.1 - 2.7 8.3 20.9 6.3 7.2 0.1 5.2 2 1 1 5 5 4 0 Tup N-terminal COG5 PF10392.9 KFP01280.1 - 2.8 8.1 8.5 0.28 11.4 0.4 3.0 3 1 1 4 4 3 0 Golgi transport complex subunit 5 KfrA_N PF11740.8 KFP01280.1 - 2.9 8.6 8.3 0.53 11.0 2.2 2.8 3 1 1 4 4 2 0 Plasmid replication region DNA-binding N-term DUF883 PF05957.13 KFP01280.1 - 2.9 8.5 13.5 1.4 9.6 2.4 4.3 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF883) CRR7 PF12095.8 KFP01280.1 - 3 8.4 8.1 1.5 9.3 0.1 3.6 4 0 0 4 4 4 0 Protein CHLORORESPIRATORY REDUCTION 7 Bap31_Bap29_C PF18035.1 KFP01280.1 - 3.1 7.9 0.0 3.1 7.9 0.0 4.2 5 1 0 5 5 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain APG6_N PF17675.1 KFP01280.1 - 3.1 8.3 28.4 0.85 10.2 4.7 4.4 2 1 2 4 4 4 0 Apg6 coiled-coil region COG2 PF06148.11 KFP01280.1 - 3.6 7.7 18.9 0.4 10.8 0.5 4.4 3 2 2 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 KELK PF15796.5 KFP01280.1 - 3.7 8.1 26.0 0.091 13.2 2.1 4.2 3 2 1 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Plk4_PB2 PF18409.1 KFP01280.1 - 4.2 8.1 6.9 65 4.3 0.2 3.6 2 1 0 3 3 3 0 Polo-like Kinase 4 Polo Box 2 ADIP PF11559.8 KFP01280.1 - 4.8 7.3 22.6 0.23 11.5 4.5 4.1 3 1 0 4 4 4 0 Afadin- and alpha -actinin-Binding DUF5082 PF16888.5 KFP01280.1 - 5 7.4 16.7 2.3 8.5 2.6 4.1 2 2 2 4 4 4 0 Domain of unknown function (DUF5082) ApoLp-III PF07464.11 KFP01280.1 - 5.1 7.2 14.1 0.26 11.4 0.9 3.8 2 1 2 4 4 4 0 Apolipophorin-III precursor (apoLp-III) DASH_Duo1 PF08651.10 KFP01280.1 - 5.5 6.8 10.5 1.2 8.9 0.3 4.0 5 0 0 5 5 4 0 DASH complex subunit Duo1 PRKG1_interact PF15898.5 KFP01280.1 - 5.8 7.9 21.4 3.9 8.4 0.2 4.3 3 2 0 4 4 4 0 cGMP-dependent protein kinase interacting domain Laminin_II PF06009.12 KFP01280.1 - 5.9 6.9 16.1 3 7.9 1.0 3.8 2 1 3 5 5 5 0 Laminin Domain II Fib_alpha PF08702.10 KFP01280.1 - 6.1 7.0 20.2 0.22 11.7 1.3 3.5 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family JIP_LZII PF16471.5 KFP01280.1 - 6.7 7.0 15.3 2.3 8.5 0.2 4.7 4 3 1 5 5 5 0 JNK-interacting protein leucine zipper II DHR10 PF18595.1 KFP01280.1 - 9.3 6.3 22.8 0.049 13.7 1.8 4.5 3 2 1 4 4 4 0 Designed helical repeat protein 10 domain CLZ PF16526.5 KFP01280.1 - 9.3 6.7 12.6 4.1 7.8 2.1 4.0 2 2 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Filament PF00038.21 KFP01281.1 - 9.4e-106 353.9 43.7 1.1e-105 353.7 43.7 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFP01281.1 - 5.6e-15 55.8 104.2 5.6e-15 55.8 104.2 5.1 2 2 2 4 4 2 1 Keratin type II head TPR_MLP1_2 PF07926.12 KFP01281.1 - 0.00025 21.1 44.2 0.0014 18.7 4.1 3.7 3 1 0 3 3 3 2 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 KFP01281.1 - 0.00038 20.7 34.5 0.0095 16.2 7.7 2.6 1 1 0 2 2 2 2 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KFP01281.1 - 0.0012 17.9 12.5 0.0012 17.9 12.5 3.1 1 1 2 3 3 3 2 Spc7 kinetochore protein AAA_13 PF13166.6 KFP01281.1 - 0.0069 15.1 28.1 0.033 12.9 28.1 2.0 1 1 0 1 1 1 1 AAA domain APG6_N PF17675.1 KFP01281.1 - 0.014 15.9 10.3 0.014 15.9 10.3 4.2 1 1 1 4 4 4 0 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 KFP01281.1 - 0.078 13.0 36.3 0.045 13.8 13.6 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.7 KFP01281.1 - 0.085 13.0 31.6 0.16 12.2 1.8 3.4 3 0 0 3 3 3 0 Tropomyosin like Fib_alpha PF08702.10 KFP01281.1 - 0.46 10.7 32.8 0.022 15.0 6.3 3.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family JIP_LZII PF16471.5 KFP01281.1 - 0.57 10.4 24.5 0.16 12.2 0.7 5.0 4 2 1 5 5 5 0 JNK-interacting protein leucine zipper II DUF883 PF05957.13 KFP01281.1 - 1.2 9.7 18.2 1.3 9.7 6.2 3.7 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) AIP3 PF03915.13 KFP01281.1 - 1.3 8.0 29.5 21 4.0 29.5 2.3 1 1 0 1 1 1 0 Actin interacting protein 3 Baculo_PEP_C PF04513.12 KFP01281.1 - 1.4 9.0 22.9 4.9 7.2 1.5 4.2 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus MscS_porin PF12795.7 KFP01281.1 - 2.8 7.4 39.2 0.12 11.9 19.9 3.0 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain FPP PF05911.11 KFP01281.1 - 3.2 5.8 31.1 7.5 4.6 31.1 1.5 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil BLOC1_2 PF10046.9 KFP01281.1 - 6.3 7.2 26.1 0.2 12.0 5.5 4.1 2 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 KFP01281.1 - 6.9 6.7 27.3 0.52 10.4 1.6 4.3 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) Alanine_zipper PF11839.8 KFP01281.1 - 8.7 6.8 9.6 8.5 6.8 6.8 2.3 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein FapA PF03961.13 KFP01281.1 - 9 4.8 31.8 1.3 7.5 8.1 2.5 1 1 2 3 3 3 0 Flagellar Assembly Protein A Filament PF00038.21 KFP01282.1 - 2.3e-105 352.6 40.0 2.7e-105 352.4 40.0 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFP01282.1 - 2.2e-22 79.9 69.5 2.2e-22 79.9 69.5 2.1 1 1 1 2 2 2 1 Keratin type II head TPR_MLP1_2 PF07926.12 KFP01282.1 - 8.3e-07 29.1 35.7 0.00035 20.6 1.7 3.7 3 1 0 3 3 3 2 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KFP01282.1 - 9.8e-05 21.4 12.1 9.8e-05 21.4 12.1 3.0 1 1 1 3 3 3 2 Spc7 kinetochore protein AAA_13 PF13166.6 KFP01282.1 - 0.00021 20.1 14.9 0.00021 20.1 14.9 1.8 1 1 0 1 1 1 1 AAA domain ATG16 PF08614.11 KFP01282.1 - 0.00069 19.9 29.0 0.011 15.9 3.1 2.5 1 1 0 2 2 2 2 Autophagy protein 16 (ATG16) JIP_LZII PF16471.5 KFP01282.1 - 0.00078 19.6 22.6 0.14 12.4 0.9 5.1 4 1 0 5 5 5 2 JNK-interacting protein leucine zipper II DUF2353 PF09789.9 KFP01282.1 - 0.0026 17.2 15.7 0.0026 17.2 15.7 2.1 1 1 1 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) Fib_alpha PF08702.10 KFP01282.1 - 0.0036 17.5 2.0 0.0036 17.5 2.0 3.5 2 1 1 3 3 3 1 Fibrinogen alpha/beta chain family aGPT-Pplase2 PF18724.1 KFP01282.1 - 0.0037 17.1 2.3 0.097 12.4 0.1 2.3 2 0 0 2 2 2 1 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 2 CENP-F_leu_zip PF10473.9 KFP01282.1 - 0.0062 16.6 31.5 0.015 15.3 15.3 3.2 1 1 3 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.12 KFP01282.1 - 0.016 15.2 14.2 0.24 11.4 1.9 4.2 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.13 KFP01282.1 - 0.04 14.3 9.2 0.061 13.7 0.7 4.1 5 0 0 5 5 3 0 Lipoprotein leucine-zipper Alanine_zipper PF11839.8 KFP01282.1 - 0.063 13.7 2.8 0.19 12.1 2.8 1.8 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein bZIP_1 PF00170.21 KFP01282.1 - 0.12 12.5 26.2 0.087 12.9 1.0 5.2 4 1 1 5 5 5 0 bZIP transcription factor Taxilin PF09728.9 KFP01282.1 - 0.16 11.1 30.1 0.013 14.7 17.6 2.5 1 1 2 3 3 3 0 Myosin-like coiled-coil protein CHDCT2 PF08074.11 KFP01282.1 - 0.19 11.9 15.4 0.033 14.4 1.7 2.7 1 1 0 2 2 2 0 CHDCT2 (NUC038) domain AKNA PF12443.8 KFP01282.1 - 0.24 12.1 10.0 4 8.1 0.8 2.6 2 0 0 2 2 2 0 AT-hook-containing transcription factor HALZ PF02183.18 KFP01282.1 - 0.41 10.9 0.1 0.41 10.9 0.1 4.6 6 0 0 6 6 3 0 Homeobox associated leucine zipper DUF2721 PF11026.8 KFP01282.1 - 0.46 10.4 0.0 0.46 10.4 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) She9_MDM33 PF05546.11 KFP01282.1 - 0.51 10.1 15.3 0.086 12.6 0.6 2.9 2 1 0 2 2 2 0 She9 / Mdm33 family ADIP PF11559.8 KFP01282.1 - 0.53 10.4 32.3 0.04 14.0 12.7 3.5 2 2 2 4 4 4 0 Afadin- and alpha -actinin-Binding CALCOCO1 PF07888.11 KFP01282.1 - 0.53 9.1 36.0 3.1 6.5 10.5 2.3 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4618 PF15397.6 KFP01282.1 - 0.6 9.5 33.0 0.03 13.8 10.8 3.4 1 1 1 3 3 3 0 Domain of unknown function (DUF4618) WD40_alt PF14077.6 KFP01282.1 - 0.96 9.4 3.9 97 3.0 0.0 4.0 3 1 1 4 4 3 0 Alternative WD40 repeat motif DUF1664 PF07889.12 KFP01282.1 - 1.2 9.2 23.0 0.48 10.5 3.7 4.3 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) Cnn_1N PF07989.11 KFP01282.1 - 1.7 8.9 22.4 4.2 7.6 4.0 4.0 2 2 1 3 3 3 0 Centrosomin N-terminal motif 1 PIN_2 PF10130.9 KFP01282.1 - 1.7 8.9 7.8 4.5 7.5 0.1 3.1 2 1 1 3 3 3 0 PIN domain Syntaxin-6_N PF09177.11 KFP01282.1 - 2.2 8.9 18.0 3.5 8.2 7.7 3.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Rootletin PF15035.6 KFP01282.1 - 2.3 8.2 31.1 0.89 9.6 13.4 2.9 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion BLOC1_2 PF10046.9 KFP01282.1 - 2.4 8.5 20.1 1.1 9.5 1.1 4.5 2 2 2 5 5 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 COG5 PF10392.9 KFP01282.1 - 3.2 7.9 9.7 1.1 9.4 5.1 2.4 2 1 0 2 2 2 0 Golgi transport complex subunit 5 FlaC_arch PF05377.11 KFP01282.1 - 4.1 7.9 23.3 0.089 13.2 2.0 5.6 5 1 1 6 6 5 0 Flagella accessory protein C (FlaC) DUF883 PF05957.13 KFP01282.1 - 5.5 7.7 18.2 3.1 8.5 5.9 3.6 3 1 0 4 4 3 0 Bacterial protein of unknown function (DUF883) FapA PF03961.13 KFP01282.1 - 5.8 5.4 28.5 1.3 7.6 5.3 2.7 1 1 2 3 3 3 0 Flagellar Assembly Protein A DUF4407 PF14362.6 KFP01282.1 - 5.9 6.1 23.3 1.4e+04 -4.9 23.3 2.5 1 1 0 1 1 0 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 KFP01282.1 - 7.4 5.6 25.1 4.8 6.2 1.3 2.2 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 KFP01282.1 - 7.6 7.1 40.5 0.45 11.0 14.8 4.0 1 1 3 4 4 4 0 Apg6 coiled-coil region DivIVA PF05103.13 KFP01282.1 - 7.9 6.6 29.0 3.3 7.8 11.2 4.2 3 1 1 4 4 4 0 DivIVA protein Lectin_N PF03954.14 KFP01282.1 - 8.1 6.2 11.6 1.8 8.3 3.0 3.2 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain UPF0242 PF06785.11 KFP01282.1 - 8.6 6.4 37.1 9.4 6.3 7.1 3.4 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus FUSC PF04632.12 KFP01282.1 - 9.2 4.7 7.7 13 4.1 5.7 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein family Rx_N PF18052.1 KFP01282.1 - 9.7 6.5 11.2 4.7 7.6 2.5 3.2 3 1 0 3 3 2 0 Rx N-terminal domain Filament PF00038.21 KFP01283.1 - 1e-105 353.8 40.2 1.2e-105 353.6 40.2 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFP01283.1 - 1.6e-17 64.1 54.0 1.6e-17 64.1 54.0 3.7 2 1 1 3 3 3 1 Keratin type II head TPR_MLP1_2 PF07926.12 KFP01283.1 - 9.7e-06 25.7 37.9 0.00052 20.1 1.4 3.6 3 1 0 3 3 3 2 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KFP01283.1 - 0.00014 20.9 12.0 0.00014 20.9 12.0 3.1 1 1 2 3 3 3 2 Spc7 kinetochore protein AAA_13 PF13166.6 KFP01283.1 - 0.00086 18.1 17.6 0.0014 17.4 17.0 1.6 1 1 0 1 1 1 1 AAA domain JIP_LZII PF16471.5 KFP01283.1 - 0.002 18.2 22.3 0.17 12.1 0.9 4.8 4 1 2 6 6 6 2 JNK-interacting protein leucine zipper II ATG16 PF08614.11 KFP01283.1 - 0.0029 17.8 28.7 0.035 14.3 2.7 2.5 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 KFP01283.1 - 0.0068 16.6 2.0 0.0068 16.6 2.0 3.3 2 1 1 3 3 3 1 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 KFP01283.1 - 0.014 15.5 12.2 0.26 11.3 1.9 4.0 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.13 KFP01283.1 - 0.017 15.5 7.5 0.076 13.4 0.7 4.0 5 0 0 5 5 4 0 Lipoprotein leucine-zipper CENP-F_leu_zip PF10473.9 KFP01283.1 - 0.024 14.7 32.3 0.021 14.9 15.3 3.3 1 1 2 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 aGPT-Pplase2 PF18724.1 KFP01283.1 - 0.051 13.3 1.8 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 2 Alanine_zipper PF11839.8 KFP01283.1 - 0.092 13.1 2.8 0.24 11.8 2.8 1.7 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein ADIP PF11559.8 KFP01283.1 - 0.13 12.4 30.2 0.066 13.3 12.9 3.3 2 2 2 4 4 4 0 Afadin- and alpha -actinin-Binding Taxilin PF09728.9 KFP01283.1 - 0.26 10.4 28.7 7.8 5.6 28.7 2.4 1 1 0 1 1 1 0 Myosin-like coiled-coil protein She9_MDM33 PF05546.11 KFP01283.1 - 0.55 10.0 14.8 0.087 12.6 0.5 2.8 2 1 0 2 2 2 0 She9 / Mdm33 family DUF2353 PF09789.9 KFP01283.1 - 1.2 8.4 36.8 0.099 12.0 17.1 2.6 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DUF2721 PF11026.8 KFP01283.1 - 1.3 8.9 0.0 1.3 8.9 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) bZIP_1 PF00170.21 KFP01283.1 - 1.4 9.1 28.4 0.11 12.6 1.0 5.2 4 1 1 5 5 5 0 bZIP transcription factor CALCOCO1 PF07888.11 KFP01283.1 - 1.5 7.6 35.4 9.9 4.9 11.0 2.3 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like PIN_2 PF10130.9 KFP01283.1 - 2.2 8.5 8.0 3.7 7.8 0.1 3.0 2 1 1 3 3 3 0 PIN domain COG5 PF10392.9 KFP01283.1 - 2.3 8.4 8.2 1.3 9.2 5.0 2.2 2 1 0 2 2 2 0 Golgi transport complex subunit 5 BicD PF09730.9 KFP01283.1 - 2.8 6.3 30.3 0.34 9.3 15.7 2.2 2 0 0 2 2 2 0 Microtubule-associated protein Bicaudal-D DUF948 PF06103.11 KFP01283.1 - 3.4 8.0 7.0 16 5.9 2.1 3.8 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) FapA PF03961.13 KFP01283.1 - 3.5 6.1 26.8 0.89 8.1 4.1 2.7 1 1 2 3 3 3 0 Flagellar Assembly Protein A CHDCT2 PF08074.11 KFP01283.1 - 3.5 7.8 14.9 0.65 10.2 1.7 2.7 1 1 0 2 2 2 0 CHDCT2 (NUC038) domain DUF883 PF05957.13 KFP01283.1 - 4.1 8.1 16.6 3.9 8.1 5.9 3.6 4 0 0 4 4 3 0 Bacterial protein of unknown function (DUF883) Cnn_1N PF07989.11 KFP01283.1 - 4.4 7.5 22.6 5.3 7.3 4.1 3.9 2 2 1 3 3 3 0 Centrosomin N-terminal motif 1 DUF4407 PF14362.6 KFP01283.1 - 4.6 6.5 21.4 2.1e+03 -2.2 20.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 KFP01283.1 - 4.6 7.7 22.5 0.097 13.1 1.8 5.6 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) DASH_Dam1 PF08653.10 KFP01283.1 - 5.3 6.9 5.3 31 4.5 0.1 3.6 5 0 0 5 5 3 0 DASH complex subunit Dam1 Syntaxin-6_N PF09177.11 KFP01283.1 - 5.5 7.6 17.1 3.4 8.3 7.2 3.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 KFP01283.1 - 6.6 6.8 22.5 0.58 10.2 3.6 4.2 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) Rootletin PF15035.6 KFP01283.1 - 6.9 6.6 33.4 5.9 6.9 15.6 3.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion UPF0242 PF06785.11 KFP01283.1 - 7.5 6.6 35.5 4.3 7.4 5.3 3.3 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus WXG100 PF06013.12 KFP01283.1 - 8.6 6.7 13.0 24 5.3 6.5 3.5 3 1 0 3 3 2 0 Proteins of 100 residues with WXG Lectin_N PF03954.14 KFP01283.1 - 9.3 6.0 11.3 2 8.2 2.6 3.1 2 1 0 3 3 3 0 Hepatic lectin, N-terminal domain Filament PF00038.21 KFP01284.1 - 2.7e-83 280.2 46.2 3.1e-83 279.9 46.2 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFP01284.1 - 1.4e-19 70.8 14.3 1.4e-19 70.8 14.3 2.5 2 1 0 2 2 2 1 Keratin type II head V_ATPase_I PF01496.19 KFP01284.1 - 0.00064 17.8 4.4 0.00064 17.8 4.4 2.1 2 0 0 2 2 2 1 V-type ATPase 116kDa subunit family BLOC1_2 PF10046.9 KFP01284.1 - 0.99 9.7 26.9 0.15 12.4 4.3 4.5 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CHDCT2 PF08074.11 KFP01284.1 - 2.8 8.1 19.0 1.9 8.7 5.7 2.6 1 1 0 2 2 2 0 CHDCT2 (NUC038) domain DUF643 PF04867.12 KFP01284.1 - 3.5 8.3 8.2 0.75 10.4 3.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF643) HisKA_3 PF07730.13 KFP01284.1 - 5.4 7.6 8.6 1e+02 3.5 0.0 4.1 2 1 1 3 3 3 0 Histidine kinase DUF4407 PF14362.6 KFP01284.1 - 6.1 6.1 22.8 3.4 6.9 12.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4972 PF16342.5 KFP01284.1 - 8.1 6.1 9.0 0.27 10.9 1.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4972) Filament PF00038.21 KFP01285.1 - 7.7e-88 295.1 28.5 8.8e-88 294.9 28.5 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFP01285.1 - 9.6e-12 45.3 16.6 2.1e-07 31.3 4.9 2.1 1 1 1 2 2 2 2 Keratin type II head TPR_MLP1_2 PF07926.12 KFP01285.1 - 0.028 14.5 17.7 0.037 14.1 0.3 3.7 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein L1R_F9L PF02442.17 KFP01285.1 - 0.038 13.8 0.7 0.038 13.8 0.7 1.9 1 1 1 2 2 2 0 Lipid membrane protein of large eukaryotic DNA viruses zf-C2HC_2 PF13913.6 KFP01285.1 - 0.055 13.4 0.1 0.16 11.9 0.1 1.8 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Baculo_PEP_C PF04513.12 KFP01285.1 - 0.26 11.3 1.2 1.3 9.1 0.7 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_tran_CTD PF16326.5 KFP01285.1 - 0.33 11.2 6.0 0.39 11.0 1.2 3.3 1 1 2 3 3 3 0 ABC transporter C-terminal domain PMG PF05287.12 KFP01285.1 - 0.96 9.5 7.9 0.045 13.8 1.9 1.8 2 0 0 2 2 2 0 PMG protein CHDCT2 PF08074.11 KFP01285.1 - 1.2 9.3 6.6 2.5 8.3 0.1 2.8 2 1 0 2 2 2 0 CHDCT2 (NUC038) domain DUF2652 PF10851.8 KFP01285.1 - 1.3 9.2 7.2 0.17 12.0 0.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2652) DUF5344 PF17279.2 KFP01285.1 - 1.6 9.4 5.3 0.38 11.4 0.3 2.7 4 0 0 4 4 2 0 Family of unknown function (DUF5344) DUF1664 PF07889.12 KFP01285.1 - 3.8 7.6 14.5 0.093 12.8 1.6 3.5 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 KFP01285.1 - 3.9 6.7 9.3 0.33 10.3 3.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 KFP01285.1 - 8.5 5.5 9.6 1.4 8.1 5.4 1.7 1 1 1 2 2 2 0 TMPIT-like protein Filament PF00038.21 KFP01286.1 - 5.1e-92 308.8 25.9 5.8e-92 308.6 25.9 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFP01286.1 - 2.9e-08 34.0 24.1 3.9e-06 27.1 10.2 2.1 1 1 1 2 2 2 2 Keratin type II head CENP-F_leu_zip PF10473.9 KFP01286.1 - 0.00032 20.8 6.9 0.00032 20.8 6.9 3.2 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PI3K_P85_iSH2 PF16454.5 KFP01286.1 - 0.014 15.0 1.9 0.014 15.0 1.9 3.2 2 2 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain cwf21 PF08312.12 KFP01286.1 - 0.026 14.7 2.7 0.073 13.2 0.6 2.9 2 1 0 2 2 2 0 cwf21 domain DUF1664 PF07889.12 KFP01286.1 - 0.031 14.3 8.0 0.82 9.7 0.7 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 KFP01286.1 - 0.038 14.1 18.3 0.077 13.1 0.1 3.6 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 KFP01286.1 - 0.13 12.4 17.9 0.28 11.4 9.5 3.1 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Sporozoite_P67 PF05642.11 KFP01286.1 - 3.9 5.4 7.5 5.6 4.9 7.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FliJ PF02050.16 KFP01286.1 - 4.6 7.5 16.9 0.17 12.1 3.1 3.1 3 0 0 3 3 3 0 Flagellar FliJ protein DUF5082 PF16888.5 KFP01286.1 - 5.2 7.4 13.3 11 6.4 7.6 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) CENP-H PF05837.12 KFP01286.1 - 6.5 7.2 12.9 0.12 12.7 4.5 2.3 2 1 0 2 2 2 0 Centromere protein H (CENP-H) DUF883 PF05957.13 KFP01286.1 - 7 7.3 6.0 7.9 7.2 1.9 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Filament PF00038.21 KFP01287.1 - 1.6e-112 376.1 31.9 1.9e-112 375.9 31.9 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFP01287.1 - 7.2e-36 123.8 53.0 7.2e-36 123.8 53.0 3.0 2 1 0 2 2 1 1 Keratin type II head ATG16 PF08614.11 KFP01287.1 - 2.8e-05 24.5 24.0 0.0003 21.1 5.9 3.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 KFP01287.1 - 0.00066 19.7 21.6 0.027 14.5 4.8 3.1 2 2 2 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 KFP01287.1 - 0.00073 19.6 27.0 0.0019 18.2 2.3 3.6 3 1 0 3 3 3 2 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KFP01287.1 - 0.0013 17.7 27.3 0.043 12.7 8.8 2.7 1 1 1 2 2 2 2 Spc7 kinetochore protein COG5 PF10392.9 KFP01287.1 - 0.0066 16.6 1.1 0.02 15.1 0.7 2.0 1 1 0 1 1 1 1 Golgi transport complex subunit 5 BRE1 PF08647.11 KFP01287.1 - 0.018 15.1 4.6 0.018 15.1 4.6 4.4 2 2 1 4 4 4 0 BRE1 E3 ubiquitin ligase mRNA_decap_C PF16741.5 KFP01287.1 - 0.055 12.8 0.0 13 5.2 0.0 2.4 2 0 0 2 2 2 0 mRNA-decapping enzyme C-terminus ADIP PF11559.8 KFP01287.1 - 0.059 13.5 22.5 1.6 8.8 5.4 3.9 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Taxilin PF09728.9 KFP01287.1 - 0.1 11.8 21.9 9 5.4 20.6 2.9 1 1 0 1 1 1 0 Myosin-like coiled-coil protein Lebercilin PF15619.6 KFP01287.1 - 0.37 10.4 26.0 0.046 13.4 7.1 3.0 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Baculo_PEP_C PF04513.12 KFP01287.1 - 0.62 10.1 18.7 0.074 13.1 0.5 4.0 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.12 KFP01287.1 - 1.2 9.1 21.1 2.3 8.3 1.4 3.6 2 2 2 4 4 4 0 Laminin Domain II Tup_N PF08581.10 KFP01287.1 - 1.3 9.4 20.4 2.9 8.3 0.1 5.0 3 2 3 6 6 6 0 Tup N-terminal DUF3450 PF11932.8 KFP01287.1 - 1.5 8.1 23.3 0.26 10.6 2.3 3.9 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) Nbl1_Borealin_N PF10444.9 KFP01287.1 - 1.5 8.5 8.7 5.2 6.8 0.0 4.5 4 1 0 4 4 4 0 Nbl1 / Borealin N terminal Tropomyosin_1 PF12718.7 KFP01287.1 - 1.7 8.8 27.4 0.12 12.5 7.9 3.4 2 1 2 4 4 4 0 Tropomyosin like FapA PF03961.13 KFP01287.1 - 4.5 5.8 20.1 2.5 6.6 6.1 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 KFP01287.1 - 4.7 7.4 19.5 0.8 9.9 1.0 3.7 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family bZIP_1 PF00170.21 KFP01287.1 - 4.8 7.3 16.2 6.4 7.0 1.1 4.8 4 1 0 4 4 4 0 bZIP transcription factor DUF883 PF05957.13 KFP01287.1 - 8.2 7.1 13.0 4.6 7.9 3.2 4.0 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) DUF5082 PF16888.5 KFP01287.1 - 8.5 6.7 22.2 1.2 9.4 3.0 3.9 1 1 3 4 4 4 0 Domain of unknown function (DUF5082) ApoLp-III PF07464.11 KFP01287.1 - 8.5 6.5 13.1 0.5 10.4 1.2 3.5 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Filament PF00038.21 KFP01288.1 - 7.1e-115 383.9 34.2 8.2e-115 383.7 34.2 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFP01288.1 - 4.2e-45 153.8 55.0 4.2e-45 153.8 55.0 3.2 2 1 1 3 3 2 1 Keratin type II head TPR_MLP1_2 PF07926.12 KFP01288.1 - 1.3e-06 28.4 28.0 0.00037 20.6 10.7 3.7 3 1 0 3 3 3 2 TPR/MLP1/MLP2-like protein AAA_13 PF13166.6 KFP01288.1 - 9.5e-05 21.3 15.0 9.5e-05 21.3 15.0 1.9 1 1 1 2 2 2 1 AAA domain Spc7 PF08317.11 KFP01288.1 - 0.0014 17.6 31.4 0.046 12.6 15.9 3.1 1 1 2 3 3 3 3 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KFP01288.1 - 0.0031 17.5 26.4 0.014 15.4 6.8 3.8 1 1 3 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MukF_M PF17192.4 KFP01288.1 - 0.0045 16.8 13.8 0.038 13.7 7.1 2.3 2 0 0 2 2 2 2 MukF middle domain ApoLp-III PF07464.11 KFP01288.1 - 0.005 16.9 1.9 0.005 16.9 1.9 3.0 2 1 0 3 3 3 1 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 KFP01288.1 - 0.015 15.4 0.5 0.015 15.4 0.5 4.4 1 1 4 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus BRE1 PF08647.11 KFP01288.1 - 0.016 15.3 5.5 0.016 15.3 5.5 4.6 2 1 3 5 5 5 0 BRE1 E3 ubiquitin ligase Jnk-SapK_ap_N PF09744.9 KFP01288.1 - 0.017 15.3 1.7 0.017 15.3 1.7 3.3 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 ADIP PF11559.8 KFP01288.1 - 0.018 15.1 24.4 0.079 13.0 2.0 3.6 2 2 0 3 3 3 0 Afadin- and alpha -actinin-Binding mRNA_decap_C PF16741.5 KFP01288.1 - 0.023 14.0 0.0 3.8 6.9 0.0 2.4 2 0 0 2 2 2 0 mRNA-decapping enzyme C-terminus DUF4407 PF14362.6 KFP01288.1 - 0.068 12.5 17.7 0.069 12.5 2.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 KFP01288.1 - 0.13 12.3 14.6 2.7 8.0 1.2 4.3 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) DUF1451 PF07295.11 KFP01288.1 - 0.19 11.7 14.3 0.21 11.6 2.8 2.6 2 1 0 2 2 2 0 Zinc-ribbon containing domain COMP PF11598.8 KFP01288.1 - 0.23 12.0 3.4 34 5.0 0.5 4.0 4 0 0 4 4 3 0 Cartilage oligomeric matrix protein Rx_N PF18052.1 KFP01288.1 - 0.37 11.1 9.2 1.1 9.6 2.8 2.9 3 0 0 3 3 2 0 Rx N-terminal domain Tropomyosin_1 PF12718.7 KFP01288.1 - 0.4 10.8 28.0 2.4 8.3 11.6 3.7 2 1 1 4 4 4 0 Tropomyosin like DED PF01335.21 KFP01288.1 - 0.52 10.6 3.1 17 5.8 0.1 2.8 3 0 0 3 3 2 0 Death effector domain Golgin_A5 PF09787.9 KFP01288.1 - 1.8 7.9 29.5 0.16 11.4 9.0 3.5 1 1 3 4 4 4 0 Golgin subfamily A member 5 TSC22 PF01166.18 KFP01288.1 - 2.5 8.5 14.0 5.4 7.4 0.2 4.7 3 2 2 5 5 5 0 TSC-22/dip/bun family Rootletin PF15035.6 KFP01288.1 - 2.7 8.0 24.4 0.37 10.8 5.4 2.3 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion T7SS_ESX_EspC PF10824.8 KFP01288.1 - 2.9 8.4 6.3 1.2 9.7 1.9 2.6 1 1 1 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm ACCA PF03255.14 KFP01288.1 - 3.6 7.4 18.0 2.9 7.8 2.2 3.6 2 1 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF883 PF05957.13 KFP01288.1 - 4.1 8.1 20.0 0.75 10.4 6.0 4.4 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF883) DUF5082 PF16888.5 KFP01288.1 - 4.2 7.7 22.7 0.33 11.2 5.0 3.9 1 1 3 4 4 4 0 Domain of unknown function (DUF5082) Alanine_zipper PF11839.8 KFP01288.1 - 4.4 7.7 10.9 1.5 9.2 7.7 1.9 2 0 0 2 2 1 0 Alanine-zipper, major outer membrane lipoprotein CHDCT2 PF08074.11 KFP01288.1 - 5.3 7.2 14.1 2.2 8.4 2.4 2.8 1 1 1 3 3 3 0 CHDCT2 (NUC038) domain Sec34 PF04136.15 KFP01288.1 - 6.4 6.6 13.2 0.74 9.7 2.0 3.3 2 1 1 3 3 3 0 Sec34-like family Bap31_Bap29_C PF18035.1 KFP01288.1 - 6.4 6.9 8.9 1.7 8.7 0.2 3.7 3 1 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain Filament PF00038.21 KFP01290.1 - 5.7e-111 371.0 35.3 6.7e-111 370.8 35.3 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFP01290.1 - 1.6e-26 93.4 58.6 4.4e-24 85.4 30.1 3.2 2 1 0 2 2 2 1 Keratin type II head TPR_MLP1_2 PF07926.12 KFP01290.1 - 0.00021 21.4 37.5 0.00066 19.8 4.2 3.8 2 2 2 4 4 4 2 TPR/MLP1/MLP2-like protein ADIP PF11559.8 KFP01290.1 - 0.00041 20.5 30.1 0.011 15.8 5.8 3.9 3 1 0 3 3 3 2 Afadin- and alpha -actinin-Binding BRE1 PF08647.11 KFP01290.1 - 0.0057 16.7 4.3 0.0057 16.7 4.3 4.7 3 2 1 4 4 4 1 BRE1 E3 ubiquitin ligase Tropomyosin_1 PF12718.7 KFP01290.1 - 0.0057 16.8 9.4 0.0057 16.8 9.4 3.8 2 1 2 4 4 4 1 Tropomyosin like CENP-F_leu_zip PF10473.9 KFP01290.1 - 0.0066 16.5 5.0 0.0066 16.5 5.0 3.7 1 1 3 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_GP20 PF06810.11 KFP01290.1 - 0.0084 15.9 4.8 0.0084 15.9 4.8 4.0 2 1 1 4 4 4 1 Phage minor structural protein GP20 Spc7 PF08317.11 KFP01290.1 - 0.0088 15.0 35.9 0.033 13.1 10.6 3.1 1 1 2 3 3 3 2 Spc7 kinetochore protein TSNAXIP1_N PF15739.5 KFP01290.1 - 0.023 15.1 0.7 0.023 15.1 0.7 4.2 2 1 2 5 5 5 0 Translin-associated factor X-interacting N-terminus Alanine_zipper PF11839.8 KFP01290.1 - 0.046 14.1 4.2 0.13 12.7 3.4 2.1 2 0 0 2 2 1 0 Alanine-zipper, major outer membrane lipoprotein LPP PF04728.13 KFP01290.1 - 0.068 13.6 0.3 0.068 13.6 0.3 4.7 4 2 1 5 5 5 0 Lipoprotein leucine-zipper Bap31_Bap29_C PF18035.1 KFP01290.1 - 0.11 12.5 0.1 0.11 12.5 0.1 3.7 4 1 0 4 4 4 0 Bap31/Bap29 cytoplasmic coiled-coil domain T7SS_ESX_EspC PF10824.8 KFP01290.1 - 0.14 12.6 2.2 0.55 10.7 2.2 2.0 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm DUF4407 PF14362.6 KFP01290.1 - 0.14 11.5 21.8 0.65 9.3 1.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF1192 PF06698.11 KFP01290.1 - 0.3 11.2 5.4 10 6.3 0.3 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF1192) TSC22 PF01166.18 KFP01290.1 - 0.3 11.4 13.8 2.1 8.7 0.3 4.5 2 1 1 4 4 4 0 TSC-22/dip/bun family Fib_alpha PF08702.10 KFP01290.1 - 0.85 9.8 27.3 0.42 10.8 3.9 3.9 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Ribosomal_S30AE PF02482.19 KFP01290.1 - 1.2 10.0 7.9 0.32 11.8 2.4 2.7 3 1 0 3 3 3 0 Sigma 54 modulation protein / S30EA ribosomal protein GAS PF13851.6 KFP01290.1 - 1.3 8.3 34.1 0.4 10.0 9.2 3.7 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding COMP PF11598.8 KFP01290.1 - 1.6 9.3 6.8 7.9 7.0 1.0 3.8 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein DUF1664 PF07889.12 KFP01290.1 - 2.8 8.0 21.2 1.4 9.0 1.1 4.9 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) DUF4140 PF13600.6 KFP01290.1 - 4.6 7.7 22.0 2.1 8.8 2.2 4.9 3 2 2 5 5 5 0 N-terminal domain of unknown function (DUF4140) DUF4164 PF13747.6 KFP01290.1 - 6.1 7.2 17.7 0.15 12.4 3.1 4.0 2 2 2 4 4 4 0 Domain of unknown function (DUF4164) Golgin_A5 PF09787.9 KFP01290.1 - 6.1 6.2 32.3 0.24 10.8 7.8 3.1 1 1 2 3 3 3 0 Golgin subfamily A member 5 Atg14 PF10186.9 KFP01290.1 - 6.4 5.8 24.4 1.8 7.6 5.1 2.7 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1451 PF07295.11 KFP01290.1 - 7.7 6.5 12.7 0.49 10.4 2.2 2.8 2 1 0 2 2 2 0 Zinc-ribbon containing domain Filament PF00038.21 KFP01291.1 - 3.3e-118 394.8 37.9 3.8e-118 394.6 37.9 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFP01291.1 - 1.2e-19 71.0 42.4 1.8e-16 60.7 2.8 3.1 2 1 1 3 3 3 2 Keratin type II head TPR_MLP1_2 PF07926.12 KFP01291.1 - 7.6e-07 29.3 38.7 0.00017 21.6 12.1 3.9 2 1 2 4 4 4 3 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 KFP01291.1 - 0.0007 19.6 29.7 0.024 14.7 5.3 3.7 1 1 3 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N PF09744.9 KFP01291.1 - 0.0012 19.1 30.8 0.014 15.6 4.3 3.4 2 1 1 3 3 3 2 JNK_SAPK-associated protein-1 Spc7 PF08317.11 KFP01291.1 - 0.0014 17.5 38.5 0.0028 16.6 8.8 3.9 1 1 3 4 4 4 2 Spc7 kinetochore protein CALCOCO1 PF07888.11 KFP01291.1 - 0.0063 15.4 33.8 0.14 10.9 15.9 2.1 1 1 1 2 2 2 2 Calcium binding and coiled-coil domain (CALCOCO1) like FPP PF05911.11 KFP01291.1 - 0.047 11.9 26.1 0.35 9.0 25.9 1.9 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil ADIP PF11559.8 KFP01291.1 - 0.069 13.2 28.5 0.85 9.7 5.4 3.8 1 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 KFP01291.1 - 0.092 13.0 30.6 0.029 14.6 7.8 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF1192 PF06698.11 KFP01291.1 - 0.14 12.2 13.5 0.038 14.0 2.6 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) Baculo_PEP_C PF04513.12 KFP01291.1 - 0.24 11.4 18.7 5.8 7.0 1.5 4.1 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Duo1 PF08651.10 KFP01291.1 - 0.48 10.2 9.3 1.1 9.1 0.6 4.2 3 1 1 4 4 4 0 DASH complex subunit Duo1 Ribosomal_S30AE PF02482.19 KFP01291.1 - 0.6 10.9 11.2 0.11 13.3 3.0 3.0 2 1 1 3 3 3 0 Sigma 54 modulation protein / S30EA ribosomal protein APG6_N PF17675.1 KFP01291.1 - 0.97 10.0 43.6 0.16 12.5 6.6 4.4 1 1 4 5 5 5 0 Apg6 coiled-coil region GAS PF13851.6 KFP01291.1 - 1.8 7.9 35.8 0.21 10.9 9.8 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding TraC PF07820.12 KFP01291.1 - 2.6 8.4 14.1 3.9 7.9 6.4 3.4 3 0 0 3 3 3 0 TraC-like protein COMP PF11598.8 KFP01291.1 - 2.8 8.5 7.2 6.9 7.2 1.6 3.9 4 0 0 4 4 4 0 Cartilage oligomeric matrix protein MAD PF05557.13 KFP01291.1 - 3.5 5.9 35.1 1.6 7.0 18.5 2.5 1 1 0 2 2 2 0 Mitotic checkpoint protein IL2 PF00715.17 KFP01291.1 - 5.2 7.0 7.8 2.2 8.2 0.2 3.3 1 1 3 4 4 4 0 Interleukin 2 Fib_alpha PF08702.10 KFP01291.1 - 8.3 6.6 24.3 0.11 12.6 1.5 3.7 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Filament PF00038.21 KFP01292.1 - 1.8e-76 257.7 32.4 2.1e-76 257.5 32.4 1.0 1 0 0 1 1 1 1 Intermediate filament protein NSP2-B_epitope PF14757.6 KFP01292.1 - 0.067 12.9 0.3 0.13 11.9 0.1 1.6 1 1 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein V_ATPase_I PF01496.19 KFP01292.1 - 0.18 9.7 21.8 0.19 9.6 3.0 2.9 1 1 2 3 3 3 0 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.12 KFP01292.1 - 0.23 11.5 8.4 0.27 11.3 0.4 3.4 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.22 KFP01292.1 - 0.26 11.5 18.7 0.029 14.6 3.9 3.4 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain GAS PF13851.6 KFP01292.1 - 0.42 9.9 30.6 0.28 10.5 4.6 3.3 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding ApoLp-III PF07464.11 KFP01292.1 - 1.6 8.8 10.0 0.23 11.6 0.3 2.8 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) CSN5_C PF18323.1 KFP01292.1 - 1.8 9.5 7.8 12 6.9 1.2 2.9 2 1 1 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain DUF4407 PF14362.6 KFP01292.1 - 3.7 6.8 10.9 8.8e+02 -1.0 10.9 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 KFP01292.1 - 4.2 8.1 27.1 0.17 12.6 1.6 4.6 2 1 2 4 4 4 0 Initiation control protein YabA Dna2 PF08696.11 KFP01292.1 - 7.3 6.3 10.6 0.28 11.0 2.6 2.4 1 1 2 3 3 3 0 DNA replication factor Dna2 DUF4140 PF13600.6 KFP01292.1 - 8 7.0 12.1 16 6.0 0.1 4.2 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Bin3 PF06859.12 KFP01293.1 - 7.9e-19 68.3 0.0 1.2e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 KFP01293.1 - 3e-06 27.1 0.0 4.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP01293.1 - 2.9e-05 24.7 0.0 7.9e-05 23.3 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP01293.1 - 0.00018 22.1 0.0 0.00067 20.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP01293.1 - 0.00043 20.9 0.1 0.002 18.8 0.0 2.2 2 2 0 2 2 2 1 Methyltransferase domain Bax1-I PF01027.20 KFP01294.1 - 1.1e-13 51.6 20.7 1.2e-13 51.3 20.7 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 MIP PF00230.20 KFP01295.1 - 2.5e-80 269.4 9.2 2.9e-80 269.2 9.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein Phage_holin_Dp1 PF16938.5 KFP01295.1 - 2.2 8.6 5.5 7.6 6.8 0.3 2.8 2 1 1 3 3 3 0 Putative phage holin Dp-1 CPP1-like PF11833.8 KFP01295.1 - 9.8 5.8 8.2 95 2.5 7.9 2.6 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF2070 PF09843.9 KFP01295.1 - 9.9 4.3 11.5 21 3.2 8.8 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) MIP PF00230.20 KFP01296.1 - 1.7e-74 250.4 15.5 2e-74 250.2 15.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein O-antigen_lig PF13425.6 KFP01296.1 - 0.27 10.0 3.2 0.46 9.2 1.4 2.0 2 1 0 2 2 2 0 O-antigen ligase like membrane protein DUF2070 PF09843.9 KFP01296.1 - 7.1 4.8 15.5 3.4 5.8 8.4 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) HCO3_cotransp PF00955.21 KFP01297.1 - 8.1e-71 239.4 4.6 1.3e-70 238.6 4.6 1.3 1 0 0 1 1 1 1 HCO3- transporter family Ac76 PF05814.11 KFP01297.1 - 0.17 11.9 5.9 0.16 12.0 0.7 2.3 2 0 0 2 2 2 0 Orf76 (Ac76) Trypsin PF00089.26 KFP01298.1 - 1.8e-69 233.9 4.0 2e-69 233.8 4.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFP01298.1 - 6.1e-07 30.5 0.1 1e-06 29.7 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain 7tm_4 PF13853.6 KFP01299.1 - 4.6e-24 85.6 1.0 5.2e-24 85.5 1.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP01299.1 - 2.6e-05 23.7 3.8 3.7e-05 23.2 3.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Abhydrolase_6 PF12697.7 KFP01300.1 - 3e-21 77.0 0.0 9.9e-21 75.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFP01300.1 - 1.2e-05 25.0 0.1 7.1e-05 22.6 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFP01300.1 - 0.00028 20.3 0.0 0.00051 19.4 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KFP01300.1 - 0.0033 17.2 0.1 0.0062 16.3 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 KFP01300.1 - 0.0057 16.8 0.0 0.0085 16.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.16 KFP01300.1 - 0.02 14.7 0.1 3.8 7.2 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 KFP01300.1 - 0.029 14.3 0.2 0.066 13.1 0.1 1.6 2 0 0 2 2 2 0 Lipase (class 3) Esterase PF00756.20 KFP01300.1 - 0.045 13.4 0.2 0.12 12.0 0.2 1.7 1 1 0 1 1 1 0 Putative esterase P4Ha_N PF08336.11 KFP01301.1 - 1.4e-21 76.9 0.0 2.3e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 KFP01301.1 - 1.5e-05 25.8 0.0 2.8e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 KFP01301.1 - 0.0089 16.1 0.1 9.3 6.6 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat SPO22 PF08631.10 KFP01301.1 - 0.034 13.7 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like TPR_6 PF13174.6 KFP01301.1 - 0.2 12.4 0.3 4.6 8.1 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat SPC25 PF06703.11 KFP01302.1 - 5.5e-45 153.1 0.1 6.4e-45 152.9 0.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) LRR_4 PF12799.7 KFP01303.1 - 2.5e-17 62.7 14.0 0.00014 22.2 0.2 4.5 3 1 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFP01303.1 - 5.2e-12 44.8 8.7 0.33 11.1 0.0 6.3 6 0 0 6 6 6 4 Leucine Rich repeat LRR_8 PF13855.6 KFP01303.1 - 1.4e-10 40.7 18.1 4.3e-05 23.2 5.0 4.7 2 2 3 5 5 5 4 Leucine rich repeat LRR_9 PF14580.6 KFP01303.1 - 0.00063 19.3 0.3 0.91 9.0 0.0 2.6 2 1 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFP01303.1 - 0.021 15.3 16.1 61 4.8 0.0 7.0 4 2 0 4 4 4 0 Leucine Rich Repeat LRR_12 PF18837.1 KFP01303.1 - 1.9 8.2 4.1 1.4 8.7 0.1 2.9 3 0 0 3 3 3 0 Leucine-rich repeat ISK_Channel PF02060.15 KFP01305.1 - 2.4e-09 36.9 0.0 2.9e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Slow voltage-gated potassium channel JTB PF05439.12 KFP01305.1 - 0.19 11.8 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Jumping translocation breakpoint protein (JTB) Pkinase_Tyr PF07714.17 KFP01306.1 - 2.2e-99 331.9 0.0 2.6e-99 331.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP01306.1 - 3.6e-49 167.5 0.0 4.5e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.6 KFP01306.1 - 5.9e-16 59.1 0.2 1.2e-15 58.1 0.2 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Kdo PF06293.14 KFP01306.1 - 0.0031 16.9 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFP01306.1 - 0.0032 16.5 0.0 0.0051 15.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KFP01306.1 - 0.03 13.1 0.0 0.042 12.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Laminin_G_1 PF00054.23 KFP01307.1 - 7.2e-31 107.1 0.1 3.1e-25 88.9 0.0 2.2 2 0 0 2 2 2 2 Laminin G domain Laminin_G_2 PF02210.24 KFP01307.1 - 7.5e-24 84.7 0.0 1.4e-14 54.7 0.0 2.2 2 0 0 2 2 2 2 Laminin G domain EGF_CA PF07645.15 KFP01307.1 - 1.1e-19 70.3 58.3 7.1e-09 35.7 7.1 4.9 4 1 0 4 4 4 4 Calcium-binding EGF domain FXa_inhibition PF14670.6 KFP01307.1 - 1.1e-16 60.8 56.9 8.4e-08 32.4 10.3 4.6 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site Gla PF00594.20 KFP01307.1 - 1.3e-16 60.5 9.1 1.3e-16 60.5 9.1 2.1 2 0 0 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain EGF PF00008.27 KFP01307.1 - 4.7e-13 49.2 50.0 1.2e-06 28.7 5.6 4.7 4 0 0 4 4 4 4 EGF-like domain cEGF PF12662.7 KFP01307.1 - 1.2e-12 47.5 37.6 2.6e-07 30.5 3.3 5.6 5 0 0 5 5 5 4 Complement Clr-like EGF-like EGF_3 PF12947.7 KFP01307.1 - 7e-08 32.5 39.9 0.0016 18.6 6.2 4.7 4 0 0 4 4 4 3 EGF domain hEGF PF12661.7 KFP01307.1 - 2.3e-06 28.0 38.1 0.0026 18.3 2.5 5.1 4 1 0 4 4 4 3 Human growth factor-like EGF LNP1 PF15419.6 KFP01307.1 - 0.42 10.8 1.4 6 7.1 1.4 2.3 2 0 0 2 2 2 0 Leukemia NUP98 fusion partner 1 Arf PF00025.21 KFP01308.1 - 1.6e-42 144.9 1.9 2.6e-42 144.2 0.0 2.1 2 1 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 KFP01308.1 - 1.1e-07 32.1 0.2 2.9e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP01308.1 - 2.1e-07 30.7 0.0 4.6e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFP01308.1 - 2.6e-06 27.0 2.3 4.1e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFP01308.1 - 4e-05 23.7 0.2 0.00015 21.8 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 KFP01308.1 - 9e-05 21.8 0.0 9e-05 21.8 0.0 3.2 2 2 1 3 3 3 1 G-protein alpha subunit S1FA PF04689.13 KFP01308.1 - 1.2 9.4 6.4 11 6.3 1.6 2.8 2 0 0 2 2 2 0 DNA binding protein S1FA Syntaxin PF00804.25 KFP01309.1 - 2.7e-60 203.5 20.7 2.7e-60 203.5 20.7 1.6 2 0 0 2 2 2 1 Syntaxin HGD-D PF06050.13 KFP01309.1 - 0.0023 17.7 2.2 0.0023 17.7 2.2 1.8 1 1 1 2 2 2 1 2-hydroxyglutaryl-CoA dehydratase, D-component Terminase_6C PF17289.2 KFP01309.1 - 0.014 15.5 0.8 0.046 13.8 0.3 2.2 1 1 1 2 2 2 0 Terminase RNaseH-like domain SKA2 PF16740.5 KFP01309.1 - 0.044 13.6 17.7 0.15 11.8 5.1 3.7 2 2 2 4 4 4 0 Spindle and kinetochore-associated protein 2 DUF4988 PF16378.5 KFP01309.1 - 0.46 10.1 11.4 0.26 10.9 0.5 3.1 3 0 0 3 3 3 0 Domain of unknown function Focal_AT PF03623.13 KFP01309.1 - 0.49 10.4 14.9 0.031 14.2 3.5 2.5 1 1 0 2 2 2 0 Focal adhesion targeting region VioE PF18234.1 KFP01309.1 - 0.59 10.3 2.2 4.6 7.4 0.1 2.2 2 0 0 2 2 2 0 Violacein biosynthetic enzyme VioE Syntaxin-6_N PF09177.11 KFP01309.1 - 2.8 8.6 16.6 0.17 12.4 3.8 3.1 2 2 1 3 3 3 0 Syntaxin 6, N-terminal PCRF PF03462.18 KFP01309.1 - 2.8 7.7 14.8 3.7 7.4 5.4 2.5 2 0 0 2 2 2 0 PCRF domain MbeD_MobD PF04899.12 KFP01309.1 - 4.1 7.6 8.8 4 7.6 1.9 3.3 2 1 1 3 3 3 0 MbeD/MobD like Methyltr_RsmB-F PF01189.17 KFP01310.1 - 2.3e-30 105.7 0.0 3.3e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KFP01310.1 - 0.0023 18.1 0.1 0.017 15.3 0.1 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase Drf_FH1 PF06346.12 KFP01311.1 - 0.00014 21.6 120.2 1.1 9.0 45.4 3.3 1 1 1 2 2 2 1 Formin Homology Region 1 Trypan_PARP PF05887.11 KFP01311.1 - 1.2 9.1 39.7 1.8e+04 -24.6 39.7 4.8 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Drf_FH1 PF06346.12 KFP01312.1 - 0.00014 21.6 120.2 1.1 9.0 45.4 3.3 1 1 1 2 2 2 1 Formin Homology Region 1 Trypan_PARP PF05887.11 KFP01312.1 - 1.2 9.1 39.7 1.8e+04 -24.6 39.7 4.8 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pkinase_Tyr PF07714.17 KFP01313.1 - 1e-65 221.6 0.0 1.2e-65 221.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP01313.1 - 1.3e-26 93.5 0.0 1.6e-26 93.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 KFP01313.1 - 0.0012 17.8 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KFP01313.1 - 0.065 12.0 0.0 0.084 11.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KFP01313.1 - 0.21 10.9 0.1 0.27 10.6 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Arf PF00025.21 KFP01314.1 - 2.4e-54 183.4 0.0 2.8e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KFP01314.1 - 1.9e-13 50.3 3.4 1.2e-07 31.3 0.7 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KFP01314.1 - 6.2e-12 45.8 0.0 8.4e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP01314.1 - 7.3e-11 41.9 0.0 8.6e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFP01314.1 - 2.4e-10 40.1 0.1 3.2e-10 39.8 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFP01314.1 - 2.9e-07 30.1 0.1 3.5e-07 29.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP01314.1 - 3.7e-07 30.2 0.0 5.2e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KFP01314.1 - 0.0032 17.7 0.1 0.053 13.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 KFP01314.1 - 0.0039 16.8 0.0 0.082 12.4 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KFP01314.1 - 0.016 14.8 0.2 0.033 13.7 0.2 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_18 PF13238.6 KFP01314.1 - 0.062 13.8 0.0 0.11 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFP01314.1 - 0.16 11.9 0.1 1.1 9.1 0.0 2.0 2 1 0 2 2 2 0 RsgA GTPase STAT_bind PF02864.15 KFP01315.1 - 0.033 14.7 0.1 0.04 14.5 0.1 1.1 1 0 0 1 1 1 0 STAT protein, DNA binding domain Cupin_4 PF08007.12 KFP01316.1 - 3.5e-91 306.0 0.0 4.6e-91 305.6 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 KFP01316.1 - 3.4e-06 26.9 0.1 0.013 15.3 0.1 2.4 1 1 1 2 2 2 2 Cupin-like domain Cupin_2 PF07883.11 KFP01316.1 - 0.00073 19.2 0.1 0.013 15.2 0.1 2.2 1 1 0 1 1 1 1 Cupin domain T2SSF PF00482.23 KFP01316.1 - 0.0062 16.5 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F AraC_binding PF02311.19 KFP01316.1 - 0.069 13.1 0.1 0.3 11.0 0.1 2.1 2 1 0 2 2 2 0 AraC-like ligand binding domain MPC PF03650.13 KFP01317.1 - 1.6e-39 134.4 0.3 1.8e-39 134.3 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers V-set PF07686.17 KFP01318.1 - 1.3e-21 76.8 0.0 1.9e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFP01318.1 - 1.5e-07 31.5 0.0 6.4e-07 29.5 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFP01318.1 - 1.5e-05 25.5 0.6 7.8e-05 23.2 0.1 2.4 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFP01318.1 - 8.8e-05 22.5 0.1 0.00036 20.5 0.1 1.9 1 1 0 1 1 1 1 Immunoglobulin I-set domain Myelin-PO_C PF10570.9 KFP01318.1 - 0.032 14.6 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 2 0 Myelin-PO cytoplasmic C-term p65 binding region Ig_2 PF13895.6 KFP01318.1 - 0.079 13.3 0.1 0.8 10.1 0.1 2.2 1 1 0 1 1 1 0 Immunoglobulin domain RVT_1 PF00078.27 KFP01319.1 - 0.064 12.7 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Yae1_N PF09811.9 KFP01320.1 - 4.6e-09 35.8 28.3 42 3.9 28.3 3.9 1 1 0 1 1 1 1 Essential protein Yae1, N terminal MMtag PF10159.9 KFP01321.1 - 2e-32 111.3 1.1 2e-32 111.3 1.1 1.7 2 0 0 2 2 2 1 Multiple myeloma tumor-associated Guanylate_kin PF00625.21 KFP01322.1 - 1.2e-69 233.7 0.0 1.3e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 KFP01322.1 - 3.6e-06 27.5 0.3 1e-05 26.0 0.3 1.7 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 KFP01322.1 - 1.5e-05 25.1 0.1 5.2e-05 23.3 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KFP01322.1 - 2.7e-05 24.7 0.1 5.8e-05 23.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KFP01322.1 - 7.7e-05 23.2 0.1 0.00012 22.7 0.1 1.6 1 1 0 1 1 1 1 ABC transporter AAA_33 PF13671.6 KFP01322.1 - 0.00018 21.6 0.2 0.0013 18.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KFP01322.1 - 0.00029 20.8 0.0 0.00064 19.7 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 KFP01322.1 - 0.00042 20.6 0.0 0.0011 19.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KFP01322.1 - 0.0019 18.2 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 NTPase RNA_helicase PF00910.22 KFP01322.1 - 0.0041 17.5 0.0 0.0077 16.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 KFP01322.1 - 0.0047 16.9 0.0 0.0086 16.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 KFP01322.1 - 0.0048 16.5 0.1 0.014 15.0 0.0 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KFP01322.1 - 0.0052 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.6 KFP01322.1 - 0.0056 17.1 1.1 0.045 14.2 1.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KFP01322.1 - 0.0075 16.0 0.1 0.012 15.3 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KFP01322.1 - 0.012 15.3 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFP01322.1 - 0.013 15.8 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFP01322.1 - 0.014 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 KFP01322.1 - 0.017 15.6 0.1 0.038 14.4 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 KFP01322.1 - 0.018 14.3 0.0 0.024 13.9 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain AAA_23 PF13476.6 KFP01322.1 - 0.023 15.2 0.4 0.41 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 KFP01322.1 - 0.023 14.5 0.0 0.38 10.6 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase Rad17 PF03215.15 KFP01322.1 - 0.027 14.4 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Zeta_toxin PF06414.12 KFP01322.1 - 0.035 13.4 0.0 0.074 12.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 KFP01322.1 - 0.037 13.2 0.0 0.061 12.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 KFP01322.1 - 0.043 13.7 0.6 0.13 12.2 0.6 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KFP01322.1 - 0.045 13.7 0.1 0.25 11.4 0.0 2.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 KFP01322.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 KFP01322.1 - 0.063 13.0 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF3734 PF12536.8 KFP01322.1 - 0.1 13.0 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Patatin phospholipase TsaE PF02367.17 KFP01322.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Connexin PF00029.19 KFP01323.1 - 4.2e-108 360.5 2.2 4.2e-108 360.5 2.2 1.5 2 0 0 2 2 2 1 Connexin Connexin40_C PF16791.5 KFP01323.1 - 4.6 8.6 9.8 1.7 10.0 5.6 2.4 2 1 0 2 2 2 0 Connexin 40 C-terminal domain MEIOC PF15189.6 KFP01325.1 - 2.7e-67 225.5 0.5 3.2e-67 225.3 0.5 1.0 1 0 0 1 1 1 1 Meiosis-specific coiled-coil domain-containing protein MEIOC DUF1517 PF07466.11 KFP01325.1 - 0.12 12.5 0.1 0.15 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Vma12 PF11712.8 KFP01326.1 - 1 9.4 3.1 1.4 9.0 0.1 1.9 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Pkinase PF00069.25 KFP01327.1 - 2.1e-30 106.0 0.0 2.7e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP01327.1 - 8.1e-17 61.4 0.0 1e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP01327.1 - 0.00013 21.4 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFP01327.1 - 0.014 15.3 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family ZapB PF06005.12 KFP01328.1 - 0.0079 16.6 4.0 0.0079 16.6 4.0 7.5 5 3 2 7 7 7 2 Cell division protein ZapB OmpH PF03938.14 KFP01328.1 - 0.008 16.5 4.0 0.008 16.5 4.0 5.0 2 2 1 3 3 3 1 Outer membrane protein (OmpH-like) HALZ PF02183.18 KFP01328.1 - 0.0084 16.3 2.4 0.0084 16.3 2.4 5.8 5 1 1 6 6 6 1 Homeobox associated leucine zipper Pox_A_type_inc PF04508.12 KFP01328.1 - 0.034 14.0 9.9 1.4 8.9 0.0 5.4 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat DUF4407 PF14362.6 KFP01328.1 - 3.3 7.0 39.2 0.064 12.6 8.7 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Pro_isomerase PF00160.21 KFP01329.1 - 5e-46 156.8 0.1 1.7e-45 155.1 0.1 1.9 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SR-25 PF10500.9 KFP01329.1 - 0.00011 21.9 26.8 0.00011 21.9 26.8 9.6 4 3 4 8 8 8 2 Nuclear RNA-splicing-associated protein DUF4543 PF15076.6 KFP01330.1 - 4.2e-44 148.5 2.7 4.8e-44 148.4 2.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4543) MmlI PF09448.10 KFP01330.1 - 0.18 12.3 0.2 0.23 11.9 0.2 1.2 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase Noggin PF05806.12 KFP01331.1 - 1.2e-105 352.2 1.0 1.4e-105 352.0 1.0 1.0 1 0 0 1 1 1 1 Noggin Hydin_ADK PF17213.3 KFP01332.1 - 5.1 7.3 6.6 0.58 10.4 0.4 2.3 2 1 1 3 3 3 0 Hydin Adenylate kinase-like domain fn3 PF00041.21 KFP01333.1 - 3.7e-12 46.4 0.1 8e-12 45.3 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III domain Ank_4 PF13637.6 KFP01333.1 - 3.2e-07 30.8 0.1 1.3e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP01333.1 - 5.2e-07 29.8 0.1 0.0018 18.6 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP01333.1 - 0.00016 22.2 0.3 0.0007 20.1 0.0 2.1 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Pur_ac_phosph_N PF16656.5 KFP01333.1 - 0.028 15.0 0.1 0.1 13.1 0.1 2.0 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain START PF01852.19 KFP01334.1 - 6.2e-34 117.2 0.0 6.8e-34 117.1 0.0 1.0 1 0 0 1 1 1 1 START domain DUF3074 PF11274.8 KFP01334.1 - 0.031 14.2 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3074) TMEM100 PF16311.5 KFP01335.1 - 9.4e-66 219.4 0.3 1e-65 219.3 0.3 1.0 1 0 0 1 1 1 1 Transmembrane protein 100 PIRT PF15099.6 KFP01335.1 - 0.00014 21.4 0.3 0.00017 21.1 0.3 1.2 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family Neurensin PF14927.6 KFP01335.1 - 0.00015 21.4 1.6 0.13 12.0 0.4 2.1 1 1 1 2 2 2 2 Neurensin Claudin_2 PF13903.6 KFP01335.1 - 0.00036 20.3 0.1 0.00036 20.3 0.1 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Peptidase_U4 PF03419.13 KFP01335.1 - 0.053 12.8 0.4 0.058 12.7 0.4 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA TMEM51 PF15345.6 KFP01335.1 - 0.085 12.7 0.2 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 UPF0542 PF15086.6 KFP01335.1 - 0.096 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 LapA_dom PF06305.11 KFP01335.1 - 6.2 6.7 5.8 31 4.5 5.8 2.0 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain HlyIII PF03006.20 KFP01336.1 - 3.3e-19 69.5 22.1 4e-19 69.2 22.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related bZIP_2 PF07716.15 KFP01337.1 - 1.1e-17 63.8 12.7 2.1e-17 62.9 12.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KFP01337.1 - 7.5e-05 22.8 9.1 0.00015 21.8 9.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor Cnn_1N PF07989.11 KFP01337.1 - 0.012 15.7 0.6 0.026 14.7 0.6 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 bZIP_Maf PF03131.17 KFP01337.1 - 0.026 15.0 7.9 0.031 14.8 7.1 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor IER PF05760.12 KFP01337.1 - 0.071 13.4 0.8 0.1 12.9 0.4 1.5 1 1 1 2 2 2 0 Immediate early response protein (IER) WW PF00397.26 KFP01338.1 - 1.8e-11 43.9 0.6 3.1e-11 43.1 0.6 1.4 1 0 0 1 1 1 1 WW domain PDZ PF00595.24 KFP01338.1 - 5.8e-11 42.6 0.5 2.2e-10 40.7 0.2 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFP01338.1 - 3.9e-05 23.4 0.0 0.0002 21.2 0.0 2.2 2 0 0 2 2 2 1 PDZ domain HALZ PF02183.18 KFP01338.1 - 0.0035 17.5 3.4 0.0035 17.5 3.4 3.6 3 0 0 3 3 3 1 Homeobox associated leucine zipper Pox_A11 PF05061.13 KFP01338.1 - 0.019 14.3 4.5 0.028 13.7 3.1 1.8 1 1 1 2 2 2 0 Poxvirus A11 Protein ISG65-75 PF11727.8 KFP01338.1 - 0.5 9.6 8.2 0.18 11.0 4.6 2.0 1 1 0 2 2 2 0 Invariant surface glycoprotein DUF1664 PF07889.12 KFP01338.1 - 0.58 10.2 17.0 0.096 12.7 5.7 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 KFP01338.1 - 2.1 7.2 10.2 0.49 9.2 7.1 1.5 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF4407 PF14362.6 KFP01338.1 - 5.4 6.3 18.2 6.6 6.0 15.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) CtaG_Cox11 PF04442.14 KFP01339.1 - 1.5e-64 216.6 0.4 1.7e-64 216.4 0.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 UCR_Fe-S_N PF10399.9 KFP01339.1 - 0.26 10.7 5.6 0.76 9.2 5.6 1.7 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal VHS PF00790.19 KFP01340.1 - 6.4e-19 68.2 0.2 1.2e-18 67.3 0.2 1.4 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KFP01340.1 - 7e-18 64.7 3.0 7e-18 64.7 3.0 1.9 2 0 0 2 2 2 1 GAT domain CortBP2 PF09727.9 KFP01340.1 - 0.074 12.9 0.3 0.074 12.9 0.3 1.6 2 0 0 2 2 2 0 Cortactin-binding protein-2 Carb_anhydrase PF00194.21 KFP01341.1 - 2.8e-66 223.7 0.1 3.1e-66 223.5 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase WD40 PF00400.32 KFP01342.1 - 2.2e-07 31.4 0.0 5 8.1 0.0 6.2 6 1 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP01342.1 - 4.5e-06 26.9 0.0 2.4 8.5 0.0 4.9 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 KFP01342.1 - 0.18 11.5 0.4 7.3 6.2 0.0 2.4 1 1 1 2 2 2 0 TUP1-like enhancer of split MBT PF02820.18 KFP01343.1 - 1e-91 301.3 2.3 7.3e-28 96.7 0.1 4.3 4 0 0 4 4 4 4 mbt repeat C1_2 PF03107.16 KFP01343.1 - 0.056 13.8 3.2 3.2 8.1 0.0 3.4 3 0 0 3 3 3 0 C1 domain NDK PF00334.19 KFP01344.1 - 4.1e-56 188.7 0.0 4.6e-56 188.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase NDK PF00334.19 KFP01345.1 - 2.7e-55 186.1 0.0 3.1e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Benyvirus_14KDa PF07255.11 KFP01345.1 - 0.1 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Benyvirus 14KDa protein JIP_LZII PF16471.5 KFP01346.1 - 5.7e-30 103.3 13.1 5.7e-30 103.3 13.1 5.1 5 0 0 5 5 5 1 JNK-interacting protein leucine zipper II Jnk-SapK_ap_N PF09744.9 KFP01346.1 - 4.8e-20 72.4 12.3 4.8e-20 72.4 12.3 4.5 4 1 0 5 5 5 1 JNK_SAPK-associated protein-1 Sipho_Gp157 PF05565.11 KFP01346.1 - 0.0095 16.0 3.5 0.0095 16.0 3.5 2.9 3 0 0 3 3 3 1 Siphovirus Gp157 APG6_N PF17675.1 KFP01346.1 - 0.72 10.4 50.1 0.17 12.4 11.0 5.2 4 1 0 4 4 4 0 Apg6 coiled-coil region YabA PF06156.13 KFP01346.1 - 1.1 10.0 28.9 0.089 13.4 4.8 4.0 4 0 0 4 4 4 0 Initiation control protein YabA F-protein PF00469.20 KFP01346.1 - 3.7 7.1 11.5 0.051 13.2 2.9 2.3 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef BTG PF07742.12 KFP01347.1 - 1.4e-38 131.3 0.0 2.5e-38 130.5 0.0 1.4 1 0 0 1 1 1 1 BTG family PAM2 PF07145.15 KFP01347.1 - 4.4e-06 26.0 3.2 0.0083 15.7 0.3 2.9 2 0 0 2 2 2 2 Ataxin-2 C-terminal region RAB3GAP2_N PF14655.6 KFP01347.1 - 0.34 10.1 2.2 0.45 9.7 2.2 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Kunitz_BPTI PF00014.23 KFP01348.1 - 3.9e-31 107.0 33.5 5.7e-20 71.3 6.9 3.4 3 0 0 3 3 3 2 Kunitz/Bovine pancreatic trypsin inhibitor domain I-set PF07679.16 KFP01348.1 - 4.2e-17 62.0 0.0 7.8e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP01348.1 - 1.6e-14 54.3 0.3 4.4e-14 52.8 0.3 1.8 1 0 0 1 1 1 1 Immunoglobulin domain NTR PF01759.21 KFP01348.1 - 4.2e-11 42.6 0.0 9.1e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Ig_2 PF13895.6 KFP01348.1 - 1e-09 38.5 0.0 3.4e-09 36.9 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP01348.1 - 1.3e-09 38.1 0.0 2.7e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain WAP PF00095.21 KFP01348.1 - 6e-08 33.0 11.0 6e-08 33.0 11.0 4.4 5 1 0 5 5 5 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' V-set PF07686.17 KFP01348.1 - 3.3e-06 27.2 1.4 4.5e-05 23.6 0.1 2.9 2 1 0 2 2 2 1 Immunoglobulin V-set domain MOZART1 PF12554.8 KFP01349.1 - 0.15 11.9 0.4 0.38 10.6 0.4 1.7 1 1 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated LUC7 PF03194.15 KFP01350.1 - 1.1e-91 306.9 20.0 1.1e-91 306.9 20.0 3.4 1 1 2 3 3 3 1 LUC7 N_terminus Ion_trans PF00520.31 KFP01352.1 - 7.8e-247 814.5 72.2 7.5e-77 257.9 16.0 4.1 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 KFP01352.1 - 1.6e-15 56.7 77.7 1.2e-09 37.4 1.8 9.5 6 3 3 9 9 9 5 Polycystin cation channel MscL PF01741.18 KFP01352.1 - 0.24 11.7 4.3 21 5.4 0.1 3.7 3 0 0 3 3 3 0 Large-conductance mechanosensitive channel, MscL DUF3935 PF13071.6 KFP01352.1 - 1.1 9.9 14.9 10 6.7 1.1 5.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3935) DPM3 PF08285.11 KFP01352.1 - 1.4 9.2 9.4 4.1 7.7 0.3 4.5 4 0 0 4 4 4 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) SieB PF14163.6 KFP01352.1 - 5.9 6.4 14.4 3.8 7.0 0.1 3.9 4 0 0 4 4 4 0 Super-infection exclusion protein B TMEM208_SND2 PF05620.11 KFP01352.1 - 9.6 6.0 6.3 5.8 6.7 0.0 3.3 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 Thioredox_DsbH PF03190.15 KFP01353.1 - 1.8e-76 255.6 0.0 3.3e-76 254.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 KFP01353.1 - 2.9e-10 40.2 0.0 6e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like C5-epim_C PF06662.13 KFP01353.1 - 0.058 12.9 0.6 0.33 10.4 0.0 2.2 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus ENTH PF01417.20 KFP01354.1 - 1.6e-50 170.3 0.0 2.6e-50 169.6 0.0 1.3 1 0 0 1 1 1 1 ENTH domain UIM PF02809.20 KFP01354.1 - 8.1e-06 25.4 17.7 0.0081 16.0 2.7 3.1 2 0 0 2 2 2 2 Ubiquitin interaction motif ANTH PF07651.16 KFP01354.1 - 1.7e-05 24.0 0.0 2.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 KFP01354.1 - 0.0004 20.2 0.2 0.0016 18.3 0.1 1.9 2 0 0 2 2 2 1 VHS domain MYCBPAP PF14646.6 KFP01355.1 - 5.8e-117 391.3 0.0 1e-116 390.5 0.0 1.4 1 0 0 1 1 1 1 MYCBP-associated protein family HemN_C PF06969.16 KFP01356.1 - 3.7e-13 49.3 0.3 7.5e-13 48.3 0.3 1.6 1 0 0 1 1 1 1 HemN C-terminal domain Radical_SAM PF04055.21 KFP01356.1 - 5.8e-09 36.5 0.0 1.6e-08 35.1 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily AMP-binding PF00501.28 KFP01357.1 - 4.7e-102 341.7 0.0 5.7e-102 341.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFP01357.1 - 3.8e-18 66.2 0.1 9.9e-18 64.9 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 KFP01357.1 - 0.19 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain LRR_8 PF13855.6 KFP01358.1 - 2e-63 210.0 30.7 1.1e-17 63.6 0.1 5.3 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFP01358.1 - 3.4e-21 75.0 19.8 4.2e-05 23.8 0.1 6.6 4 2 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP01358.1 - 7.9e-17 61.4 0.0 1.4e-06 28.3 0.0 2.8 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFP01358.1 - 4.5e-10 38.6 17.0 0.18 12.4 0.0 10.1 11 0 0 11 11 11 1 Leucine Rich Repeat LRRNT PF01462.18 KFP01358.1 - 2.7e-08 33.3 7.4 2.9e-08 33.2 5.0 2.3 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 KFP01358.1 - 4.4e-08 32.8 4.8 0.056 12.9 0.0 3.5 1 1 1 3 3 3 3 Leucine-rich repeat LRRCT PF01463.24 KFP01358.1 - 0.0054 17.2 0.2 0.022 15.3 0.2 2.1 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain Rv2175c_C PF18367.1 KFP01358.1 - 0.0065 16.5 0.1 0.21 11.7 0.0 3.1 2 1 0 2 2 2 1 Rv2175c C-terminal domain of unknown function DUF3874 PF12990.7 KFP01358.1 - 0.15 12.4 0.3 1.4 9.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknonw function from B. Theta Gene description (DUF3874) LRR_8 PF13855.6 KFP01359.1 - 1.5e-11 43.9 16.2 4.1e-06 26.5 1.6 2.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFP01359.1 - 2.8e-05 24.4 13.5 0.0092 16.4 4.0 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) DUF4407 PF14362.6 KFP01359.1 - 0.0095 15.3 5.1 0.014 14.8 5.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Hid1 PF12722.7 KFP01359.1 - 0.023 12.9 4.0 0.029 12.5 4.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LRR_1 PF00560.33 KFP01359.1 - 0.03 14.8 11.6 16 6.6 0.3 4.7 5 0 0 5 5 4 0 Leucine Rich Repeat AAA_11 PF13086.6 KFP01359.1 - 0.033 14.0 6.9 0.05 13.4 6.9 1.3 1 0 0 1 1 1 0 AAA domain Presenilin PF01080.17 KFP01359.1 - 0.052 12.3 7.6 0.068 11.9 7.6 1.1 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 KFP01359.1 - 0.055 13.6 1.6 0.064 13.4 1.6 1.2 1 0 0 1 1 1 0 DDHD domain MAJIN PF15077.6 KFP01359.1 - 0.1 12.3 9.2 0.15 11.8 9.2 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein GAGA_bind PF06217.12 KFP01359.1 - 0.3 11.3 11.3 0.41 10.9 11.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family CDC45 PF02724.14 KFP01359.1 - 0.35 9.1 12.5 0.45 8.8 12.5 1.1 1 0 0 1 1 1 0 CDC45-like protein ALMT PF11744.8 KFP01359.1 - 1.2 7.9 5.8 1.5 7.6 5.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Borrelia_P83 PF05262.11 KFP01359.1 - 1.3 7.4 19.3 1.6 7.1 19.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Atrophin-1 PF03154.15 KFP01359.1 - 1.5 7.0 20.0 2.1 6.5 20.0 1.3 1 0 0 1 1 1 0 Atrophin-1 family DUF5427 PF10310.9 KFP01359.1 - 1.6 7.6 14.8 2.2 7.1 14.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Hydin_ADK PF17213.3 KFP01359.1 - 2.5 8.4 8.9 3.7 7.8 8.9 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain RR_TM4-6 PF06459.12 KFP01359.1 - 2.8 7.7 17.0 3.9 7.2 17.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 XRN_M PF17846.1 KFP01359.1 - 8.7 5.2 10.8 12 4.7 10.8 1.1 1 0 0 1 1 1 0 Xrn1 helical domain ERCC4 PF02732.15 KFP01360.1 - 6.1e-09 36.3 0.1 6.1e-09 36.3 0.1 2.5 3 1 0 3 3 3 1 ERCC4 domain Catalase-rel PF06628.12 KFP01360.1 - 0.021 15.0 0.0 0.59 10.4 0.0 2.5 2 0 0 2 2 2 0 Catalase-related immune-responsive BRF1 PF07741.13 KFP01360.1 - 0.19 12.1 8.3 1.5 9.2 0.5 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Ribosomal_L27 PF01016.19 KFP01361.1 - 1.4e-25 89.1 0.1 1.8e-25 88.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein DUF3687 PF12459.8 KFP01362.1 - 0.075 12.6 0.3 0.085 12.4 0.3 1.2 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein Xylo_C PF12529.8 KFP01363.1 - 5.2e-70 234.8 0.0 7.9e-70 234.2 0.0 1.3 1 0 0 1 1 1 1 Xylosyltransferase C terminal Branch PF02485.21 KFP01363.1 - 1.5e-55 188.4 1.9 2e-55 188.0 1.9 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Ras PF00071.22 KFP01364.1 - 3.1e-59 199.2 0.1 3.6e-59 199.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP01364.1 - 1.6e-32 112.2 0.1 2.2e-32 111.8 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP01364.1 - 4e-14 52.4 0.1 4.6e-14 52.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFP01364.1 - 5e-06 26.0 0.0 6.4e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KFP01364.1 - 9e-05 22.4 0.1 0.059 13.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFP01364.1 - 0.0024 17.9 0.0 0.0044 17.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP01364.1 - 0.0094 15.5 0.0 0.02 14.5 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Septin PF00735.18 KFP01364.1 - 0.027 13.8 0.1 0.063 12.6 0.1 1.7 1 1 0 1 1 1 0 Septin AAA_24 PF13479.6 KFP01364.1 - 0.034 13.9 0.1 0.065 13.0 0.1 1.5 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 KFP01364.1 - 0.099 11.8 0.1 0.19 10.8 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 KFP01364.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 KFP01364.1 - 0.2 10.7 0.4 15 4.6 0.0 2.6 1 1 1 2 2 2 0 G-protein alpha subunit EBP50_C PF09007.11 KFP01365.1 - 2.6e-41 141.7 3.1 3.5e-41 141.2 3.1 1.2 1 0 0 1 1 1 1 EBP50, C-terminal PDZ_6 PF17820.1 KFP01365.1 - 5.1e-16 58.3 0.4 7.8e-16 57.7 0.4 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFP01365.1 - 4.7e-14 52.5 0.0 7.7e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP01365.1 - 3.9e-06 27.1 0.0 7.3e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KFP01365.1 - 0.028 14.7 0.0 0.041 14.2 0.0 1.3 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Aa_trans PF01490.18 KFP01366.1 - 1.7e-18 66.6 32.0 2.4e-10 39.7 20.7 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KFP01366.1 - 6.6e-07 28.7 20.2 0.0005 19.2 1.2 2.6 2 1 0 2 2 2 2 Tryptophan/tyrosine permease family Cytomega_UL84 PF06284.11 KFP01366.1 - 0.07 11.6 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Pyr_redox_2 PF07992.14 KFP01367.1 - 7e-08 32.0 0.0 0.00062 19.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FA_desaturase PF00487.24 KFP01368.1 - 1.2e-14 54.7 13.6 1.6e-14 54.3 13.6 1.1 1 0 0 1 1 1 1 Fatty acid desaturase TauE PF01925.19 KFP01368.1 - 0.17 11.5 8.5 2.1 7.9 0.9 2.1 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE Ank_2 PF12796.7 KFP01369.1 - 9.2e-29 99.9 0.5 1.9e-15 57.2 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP01369.1 - 2.3e-22 79.0 4.5 2.8e-12 46.9 0.2 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFP01369.1 - 3.2e-13 49.5 2.5 3.2e-07 30.5 0.2 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KFP01369.1 - 1.3e-12 47.7 1.1 4.7e-07 30.0 0.3 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP01369.1 - 1.7e-12 46.4 0.8 4.5e-05 23.5 0.2 4.0 4 0 0 4 4 4 3 Ankyrin repeat SAM_1 PF00536.30 KFP01369.1 - 1.5e-10 41.3 0.1 7.7e-10 39.1 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SR-25 PF10500.9 KFP01369.1 - 1.7 8.2 12.3 2.8 7.5 12.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Otopetrin PF03189.13 KFP01370.1 - 1.7e-52 178.8 32.6 2.5e-22 79.3 7.3 4.5 3 1 1 4 4 4 3 Otopetrin SdpI PF13630.6 KFP01370.1 - 0.018 15.1 2.1 0.018 15.1 2.1 4.0 3 0 0 3 3 3 0 SdpI/YhfL protein family DUF5345 PF17280.2 KFP01370.1 - 0.085 12.8 0.2 0.085 12.8 0.2 3.4 4 0 0 4 4 4 0 Family of unknown function (DUF5345) DUF4149 PF13664.6 KFP01370.1 - 0.18 12.1 9.8 4.8 7.6 0.7 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) Adipogenin PF15202.6 KFP01370.1 - 0.69 10.0 4.4 0.41 10.7 0.2 2.8 3 0 0 3 3 3 0 Adipogenin Otopetrin PF03189.13 KFP01371.1 - 5.2e-39 134.3 45.0 2.1e-17 63.1 14.6 4.3 3 1 1 4 4 4 3 Otopetrin Hid1 PF12722.7 KFP01372.1 - 3.3e-277 921.9 0.0 3.8e-277 921.7 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KFP01372.1 - 2.6e-256 852.0 0.0 2.9e-256 851.9 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Orbi_VP4 PF05059.12 KFP01373.1 - 0.021 12.9 0.0 0.031 12.3 0.0 1.2 1 0 0 1 1 1 0 Orbivirus VP4 core protein zf-ZPR1 PF03367.13 KFP01373.1 - 0.065 13.1 0.4 0.065 13.1 0.4 3.8 3 1 1 4 4 4 0 ZPR1 zinc-finger domain DUF3540 PF12059.8 KFP01373.1 - 0.19 11.5 10.8 0.33 10.7 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3540) BLOC1_2 PF10046.9 KFP01373.1 - 1.4 9.2 35.8 0.068 13.5 13.9 4.9 3 3 2 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliD_C PF07195.12 KFP01373.1 - 2 7.8 18.2 0.54 9.6 4.9 3.7 3 1 1 4 4 4 0 Flagellar hook-associated protein 2 C-terminus Lectin_N PF03954.14 KFP01373.1 - 3 7.6 22.0 0.56 10.0 0.7 4.6 3 1 0 4 4 4 0 Hepatic lectin, N-terminal domain DUF1664 PF07889.12 KFP01373.1 - 4.7 7.3 31.3 1.9 8.5 4.9 4.5 4 2 1 5 5 5 0 Protein of unknown function (DUF1664) AIP3 PF03915.13 KFP01373.1 - 4.9 6.1 33.7 1.2 8.2 11.5 3.2 3 0 0 3 3 3 0 Actin interacting protein 3 RF-1 PF00472.20 KFP01374.1 - 1.5e-19 70.0 2.7 2e-19 69.7 2.7 1.1 1 0 0 1 1 1 1 RF-1 domain Neur_chan_LBD PF02931.23 KFP01375.1 - 1.6e-22 80.1 0.5 1.9e-22 79.8 0.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP01375.1 - 0.019 15.0 1.3 0.027 14.5 1.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mt_ATP-synt_D PF05873.12 KFP01376.1 - 1.2e-48 164.9 8.1 1.3e-48 164.7 8.1 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) E3_UbLigase_R4 PF13764.6 KFP01376.1 - 0.051 11.8 0.1 0.058 11.6 0.1 1.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 DUF5471 PF17565.2 KFP01376.1 - 0.065 13.5 1.3 0.098 13.0 1.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5471) BTB_2 PF02214.22 KFP01377.1 - 2e-11 44.1 0.0 3.5e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KFP01377.1 - 0.015 15.6 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain SAM_LFY PF01698.16 KFP01377.1 - 0.056 13.4 0.2 0.36 10.8 0.0 2.0 2 0 0 2 2 2 0 Floricaula / Leafy protein SAM domain Arm PF00514.23 KFP01378.1 - 2.6e-12 46.3 0.1 3.4e-06 26.9 0.0 3.0 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat RICTOR_N PF14664.6 KFP01378.1 - 0.0011 18.0 0.3 0.0024 16.9 0.2 1.4 1 1 1 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term Arm_2 PF04826.13 KFP01378.1 - 0.002 17.6 0.3 0.7 9.3 0.1 2.0 1 1 1 2 2 2 2 Armadillo-like Atx10homo_assoc PF09759.9 KFP01378.1 - 0.0036 17.3 0.2 1.2 9.2 0.0 2.2 1 1 1 2 2 2 2 Spinocerebellar ataxia type 10 protein domain KAP PF05804.12 KFP01378.1 - 0.016 13.4 0.1 0.02 13.1 0.1 1.1 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) Adaptin_N PF01602.20 KFP01378.1 - 0.023 13.2 1.4 0.083 11.4 1.3 1.7 1 1 1 2 2 2 0 Adaptin N terminal region HEAT_2 PF13646.6 KFP01378.1 - 0.043 14.2 0.0 2.6 8.5 0.0 2.3 1 1 1 2 2 2 0 HEAT repeats ParcG PF10274.9 KFP01378.1 - 0.045 13.9 0.1 0.058 13.5 0.1 1.2 1 0 0 1 1 1 0 Parkin co-regulated protein NT5C PF06941.12 KFP01379.1 - 3.6e-18 66.1 0.1 4e-18 65.9 0.1 1.0 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) JUPITER PF17054.5 KFP01380.1 - 4.2e-05 23.2 0.1 4.2e-05 23.2 0.1 1.9 2 1 0 2 2 2 1 Microtubule-Associated protein Jupiter Rad60-SLD PF11976.8 KFP01381.1 - 4.2e-26 90.6 0.1 5e-26 90.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KFP01381.1 - 2.2e-12 46.5 0.1 2.6e-12 46.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S7 PF00177.21 KFP01382.1 - 5.1e-41 139.8 0.1 6.5e-41 139.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF719 PF05334.13 KFP01382.1 - 0.044 14.0 0.4 0.088 13.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF719) DUF2288 PF10052.9 KFP01382.1 - 0.06 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2288) Mito_carr PF00153.27 KFP01383.1 - 3.4e-65 216.0 2.9 1.8e-22 79.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SH3_1 PF00018.28 KFP01384.1 - 6.6e-36 121.7 0.3 8.4e-17 60.5 0.1 2.6 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 KFP01384.1 - 3.8e-32 109.9 0.2 1.8e-15 56.5 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KFP01384.1 - 3.1e-28 97.2 0.0 1.1e-15 57.0 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH2 PF00017.24 KFP01384.1 - 1.3e-24 86.1 0.0 2.1e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 SH2 domain SH3_10 PF17902.1 KFP01384.1 - 1.6e-06 28.0 0.0 0.00048 20.2 0.0 2.5 2 1 0 2 2 2 1 SH3 domain SH2_2 PF14633.6 KFP01384.1 - 0.0043 16.5 0.0 0.0062 16.0 0.0 1.3 1 0 0 1 1 1 1 SH2 domain hSH3 PF14603.6 KFP01384.1 - 0.0074 16.7 0.0 0.078 13.4 0.0 2.3 2 0 0 2 2 2 1 Helically-extended SH3 domain SH3_3 PF08239.11 KFP01384.1 - 0.0077 16.5 0.1 0.054 13.8 0.0 2.1 2 0 0 2 2 2 1 Bacterial SH3 domain DUF5093 PF17011.5 KFP01384.1 - 0.019 15.2 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5093) SH3_4 PF06347.13 KFP01384.1 - 0.029 14.2 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain tRNA_int_end_N2 PF12928.7 KFP01385.1 - 7.3e-18 64.5 1.9 9.2e-18 64.2 0.2 2.1 2 0 0 2 2 2 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 KFP01385.1 - 0.014 15.0 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain MyTH4 PF00784.17 KFP01386.1 - 6.8e-32 110.2 0.6 5.3e-31 107.3 0.1 2.5 2 0 0 2 2 2 1 MyTH4 domain FERM_M PF00373.18 KFP01386.1 - 8.3e-12 45.6 0.9 8.3e-12 45.6 0.9 1.9 2 0 0 2 2 2 1 FERM central domain RecQ5 PF06959.11 KFP01387.1 - 3.3e-28 99.1 14.6 1.1e-27 97.4 14.6 1.9 1 0 0 1 1 1 1 RecQ helicase protein-like 5 (RecQ5) DEAD PF00270.29 KFP01387.1 - 3.7e-20 72.4 0.1 7.5e-20 71.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP01387.1 - 7.6e-16 58.4 0.0 5.5e-12 46.0 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KFP01387.1 - 9.5e-10 39.1 2.3 3.1e-09 37.4 2.3 2.0 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 KFP01387.1 - 0.00023 21.2 0.1 0.00082 19.4 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TFIIS_M PF07500.14 KFP01387.1 - 0.0055 17.2 0.0 0.031 14.7 0.0 2.3 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain SRI PF08236.11 KFP01387.1 - 0.012 15.8 2.7 0.014 15.5 0.3 2.4 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain FKBP26_C PF18046.1 KFP01387.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 FKBP26_C-terminal DUF4713 PF15831.5 KFP01388.1 - 2.6e-23 82.2 12.5 3.1e-23 82.0 12.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4713) DUF3593 PF12159.8 KFP01388.1 - 0.00081 19.4 0.0 0.00096 19.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3593) Shisa PF13908.6 KFP01388.1 - 0.0037 17.5 2.2 0.0037 17.5 2.2 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Corona_S2 PF01601.16 KFP01388.1 - 0.012 14.2 3.7 0.012 14.2 3.7 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Prominin PF05478.11 KFP01388.1 - 0.5 8.2 7.0 0.49 8.3 7.0 1.1 1 0 0 1 1 1 0 Prominin FAM163 PF15069.6 KFP01388.1 - 1.4 9.3 7.8 1.7 9.0 7.8 1.2 1 0 0 1 1 1 0 FAM163 family HCNGP PF07818.13 KFP01389.1 - 2e-34 118.1 0.3 3.4e-34 117.4 0.3 1.4 1 0 0 1 1 1 1 HCNGP-like protein Na_trans_assoc PF06512.13 KFP01389.1 - 0.38 11.0 10.2 0.11 12.7 6.2 2.0 2 0 0 2 2 2 0 Sodium ion transport-associated GalKase_gal_bdg PF10509.9 KFP01390.1 - 1.1e-19 69.7 0.1 2.5e-19 68.6 0.1 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 KFP01390.1 - 4.2e-15 55.9 0.0 8.5e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 KFP01390.1 - 5.3e-14 52.2 0.3 1.6e-13 50.7 0.3 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain DUF1681 PF07933.14 KFP01391.1 - 0.026 14.3 0.0 0.032 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1681) Histone PF00125.24 KFP01392.1 - 9.4e-54 181.3 2.1 1e-53 181.1 2.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KFP01392.1 - 8e-05 22.7 0.4 0.00016 21.7 0.0 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KFP01392.1 - 0.00018 22.1 2.4 0.00023 21.7 2.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 KFP01392.1 - 0.00028 21.2 0.0 0.00042 20.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KFP01392.1 - 0.053 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf_CCCH_5 PF18384.1 KFP01393.1 - 7.1e-21 74.0 13.3 7.1e-21 74.0 13.3 3.9 3 1 0 3 3 3 1 Unkempt Zinc finger domain 1 (Znf1) zf-CCCH PF00642.24 KFP01393.1 - 4.2e-05 23.3 1.0 4.2e-05 23.3 1.0 7.1 8 1 0 8 8 6 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KFP01393.1 - 0.00011 22.0 10.6 0.00011 22.0 10.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 KFP01393.1 - 0.00058 19.8 0.5 0.051 13.7 0.0 6.3 6 1 0 6 6 5 2 Zinc finger domain DUF3450 PF11932.8 KFP01393.1 - 0.00065 19.1 5.2 0.001 18.4 5.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) THOC7 PF05615.13 KFP01393.1 - 0.0041 17.4 0.5 0.0041 17.4 0.5 1.6 2 0 0 2 2 1 1 Tho complex subunit 7 Laminin_II PF06009.12 KFP01393.1 - 0.0042 17.1 0.9 0.008 16.2 0.9 1.4 1 0 0 1 1 1 1 Laminin Domain II Fez1 PF06818.15 KFP01393.1 - 0.0065 16.9 8.3 0.013 15.9 8.3 1.5 1 0 0 1 1 1 1 Fez1 Sds3 PF08598.11 KFP01393.1 - 0.057 13.4 1.8 0.12 12.4 1.8 1.5 1 0 0 1 1 1 0 Sds3-like Torus PF16131.5 KFP01393.1 - 0.12 13.1 0.3 0.12 13.1 0.3 5.8 4 2 2 6 6 6 0 Torus domain RRP36 PF06102.12 KFP01393.1 - 0.32 10.9 5.3 0.32 11.0 2.3 2.2 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 Alanine_zipper PF11839.8 KFP01393.1 - 0.35 11.3 5.8 0.79 10.1 5.8 1.5 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein DUF3560 PF12083.8 KFP01393.1 - 0.47 10.6 4.4 0.87 9.7 3.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) DUF2205 PF10224.9 KFP01393.1 - 0.52 10.3 4.5 0.26 11.3 1.2 2.2 2 0 0 2 2 2 0 Short coiled-coil protein CENP-Q PF13094.6 KFP01393.1 - 1.4 9.1 7.2 3 8.0 7.2 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Ribosomal_S27e PF01667.17 KFP01393.1 - 1.6 8.5 7.3 4.2 7.2 7.3 1.6 1 0 0 1 1 1 0 Ribosomal protein S27 PRKG1_interact PF15898.5 KFP01393.1 - 1.8 9.5 9.0 0.7 10.8 4.6 2.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF3584 PF12128.8 KFP01393.1 - 5.4 4.4 12.2 7.3 4.0 12.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ERM PF00769.19 KFP01393.1 - 6.3 6.5 13.1 11 5.8 13.1 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family C2 PF00168.30 KFP01394.1 - 3.2e-31 107.7 0.0 2.3e-15 56.8 0.0 3.9 2 1 0 2 2 2 2 C2 domain Membr_traf_MHD PF10540.9 KFP01394.1 - 5.4e-13 49.4 16.6 2e-08 34.6 0.3 3.8 3 2 1 4 4 4 2 Munc13 (mammalian uncoordinated) homology domain DUF4795 PF16043.5 KFP01394.1 - 0.029 14.0 8.4 0.019 14.6 0.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) GRAM PF02893.20 KFP01395.1 - 2.2e-15 56.5 0.0 3e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.8 KFP01395.1 - 0.019 15.1 0.0 0.03 14.5 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.6 KFP01395.1 - 0.036 14.4 0.0 0.054 13.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial PH domain SPRY PF00622.28 KFP01396.1 - 1.6e-05 25.0 0.4 3.8e-05 23.8 0.4 1.6 1 0 0 1 1 1 1 SPRY domain zf-B_box PF00643.24 KFP01396.1 - 0.0007 19.7 7.2 0.0017 18.5 7.2 1.7 1 0 0 1 1 1 1 B-box zinc finger PRY PF13765.6 KFP01396.1 - 0.0012 18.5 0.0 0.0033 17.0 0.0 1.8 1 0 0 1 1 1 1 SPRY-associated domain COG2 PF06148.11 KFP01396.1 - 0.055 13.5 0.8 0.16 12.0 0.8 1.8 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 FlaC_arch PF05377.11 KFP01396.1 - 0.15 12.5 2.8 0.27 11.7 1.8 1.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF5104 PF17117.5 KFP01396.1 - 0.16 12.4 0.1 25 5.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5104) zf-RING_UBOX PF13445.6 KFP01397.1 - 4.6e-12 45.7 6.0 5.3e-12 45.6 6.0 1.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFP01397.1 - 1.3e-11 44.5 3.1 1.5e-11 44.2 3.1 1.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KFP01397.1 - 1.2e-09 37.8 4.0 1.4e-09 37.6 4.0 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP01397.1 - 8.6e-09 35.1 4.2 9.9e-09 34.9 4.2 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP01397.1 - 2.7e-07 30.3 3.3 2.8e-07 30.3 3.3 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP01397.1 - 8.2e-07 29.3 5.3 9.3e-07 29.1 5.3 1.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFP01397.1 - 1.1e-06 28.5 5.0 1.4e-06 28.2 5.0 1.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 KFP01397.1 - 2.7e-06 27.2 1.5 3e-06 27.0 1.5 1.0 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 KFP01397.1 - 0.00016 21.3 3.9 0.0005 19.8 3.9 1.8 1 1 0 1 1 1 1 RING-like zinc finger U-box PF04564.15 KFP01397.1 - 0.00039 20.5 0.0 0.00044 20.4 0.0 1.1 1 0 0 1 1 1 1 U-box domain zf-RING_10 PF16685.5 KFP01397.1 - 0.001 19.2 3.7 0.0012 18.9 3.7 1.1 1 0 0 1 1 1 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 KFP01397.1 - 0.0012 18.7 5.1 0.0015 18.3 5.1 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 IBR PF01485.21 KFP01397.1 - 1.4 9.2 7.7 5.2 7.4 7.7 1.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain PBP PF01161.20 KFP01398.1 - 2.7e-11 43.9 0.2 4.6e-11 43.2 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein CTK3_C PF12350.8 KFP01398.1 - 0.12 12.5 1.4 0.28 11.3 1.4 1.6 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 C-terminus DGF-1_C PF11040.8 KFP01399.1 - 0.44 10.6 5.0 15 5.7 0.2 3.7 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus adh_short PF00106.25 KFP01400.1 - 7.5e-42 143.0 0.0 9.9e-42 142.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP01400.1 - 1.7e-23 83.4 0.0 2.2e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP01400.1 - 8.6e-07 29.0 0.0 1.2e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFP01400.1 - 0.00067 19.1 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) GSG-1 PF07803.11 KFP01401.1 - 1.2e-45 154.1 0.4 2.2e-45 153.3 0.4 1.4 1 0 0 1 1 1 1 GSG1-like protein PMP22_Claudin PF00822.20 KFP01401.1 - 1.6e-07 31.4 10.0 3e-07 30.5 10.0 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP01401.1 - 0.00023 21.0 14.0 0.0012 18.7 13.8 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF872 PF05915.12 KFP01401.1 - 0.12 12.6 0.2 0.2 11.8 0.2 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) CD20 PF04103.15 KFP01401.1 - 2.8 8.0 14.0 16 5.5 8.2 3.7 3 1 0 3 3 3 0 CD20-like family 7tm_2 PF00002.24 KFP01402.1 - 7.1e-80 267.8 17.9 9e-80 267.5 17.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFP01402.1 - 3.9e-14 52.7 4.1 8.9e-14 51.5 4.1 1.6 1 0 0 1 1 1 1 Hormone receptor domain SUR7 PF06687.12 KFP01402.1 - 0.0037 16.9 1.7 0.0038 16.9 0.1 1.8 2 0 0 2 2 2 1 SUR7/PalI family WW_FCH_linker PF16623.5 KFP01403.1 - 7e-43 145.3 3.2 2.2e-42 143.7 3.2 1.9 1 0 0 1 1 1 1 Unstructured linker region between on GAS7 protein FCH PF00611.23 KFP01403.1 - 1.6e-14 53.9 4.2 1.6e-14 53.9 4.2 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain WW PF00397.26 KFP01403.1 - 8e-13 48.2 4.6 1.7e-12 47.2 4.6 1.6 1 0 0 1 1 1 1 WW domain SH3_9 PF14604.6 KFP01403.1 - 1.2e-11 44.3 0.1 2.5e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP01403.1 - 4.3e-10 39.1 0.1 8.1e-10 38.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP01403.1 - 5.6e-08 32.4 0.0 1.1e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_16 PF18348.1 KFP01403.1 - 0.0064 16.3 0.3 0.018 14.8 0.3 1.8 1 0 0 1 1 1 1 Bacterial dipeptidyl-peptidase Sh3 domain DUF1664 PF07889.12 KFP01403.1 - 0.11 12.5 9.2 0.025 14.6 4.2 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Lectin_N PF03954.14 KFP01403.1 - 1.1 9.0 5.4 0.43 10.3 2.3 2.0 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain PMC2NT PF08066.12 KFP01403.1 - 1.5 9.6 5.1 8.5 7.1 0.3 2.8 1 1 1 2 2 2 0 PMC2NT (NUC016) domain Myosin_head PF00063.21 KFP01404.1 - 3.6e-286 950.8 1.8 3.6e-286 950.8 1.8 3.2 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KFP01404.1 - 2.1e-152 509.4 268.2 2.5e-152 509.1 268.2 1.0 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 KFP01404.1 - 7.2e-14 51.3 3.6 2.1e-13 49.8 3.6 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain DUF4537 PF15057.6 KFP01404.1 - 0.0017 18.4 0.3 0.019 15.0 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4537) IQ PF00612.27 KFP01404.1 - 0.002 17.8 0.2 0.011 15.5 0.0 2.3 2 0 0 2 2 2 1 IQ calmodulin-binding motif Syntaxin-6_N PF09177.11 KFP01404.1 - 0.0081 16.7 6.7 0.0081 16.7 6.7 13.0 2 2 5 10 10 10 1 Syntaxin 6, N-terminal HALZ PF02183.18 KFP01404.1 - 0.015 15.5 1.4 0.015 15.5 1.4 14.8 14 3 2 16 16 16 0 Homeobox associated leucine zipper AAA_22 PF13401.6 KFP01404.1 - 0.2 11.9 0.1 0.2 11.9 0.1 5.2 3 2 1 4 4 4 0 AAA domain AAA_16 PF13191.6 KFP01404.1 - 0.22 11.9 0.0 0.22 11.9 0.0 5.3 2 1 0 2 2 2 0 AAA ATPase domain TIR_2 PF13676.6 KFP01404.1 - 7.9 7.1 8.7 2 9.1 2.6 3.2 2 1 1 3 3 3 0 TIR domain Myosin_head PF00063.21 KFP01407.1 - 6.5e-287 953.3 1.5 6.5e-287 953.3 1.5 3.1 4 1 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KFP01407.1 - 5.2e-129 431.9 239.2 3.5e-101 339.7 166.5 2.1 1 1 1 2 2 2 2 Myosin tail Myosin_N PF02736.19 KFP01407.1 - 2.3e-13 49.7 1.8 6.5e-13 48.3 1.8 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain DUF1664 PF07889.12 KFP01407.1 - 0.0034 17.4 8.0 0.0034 17.4 8.0 12.6 3 2 7 12 12 12 5 Protein of unknown function (DUF1664) BRE1 PF08647.11 KFP01407.1 - 0.0036 17.3 11.1 0.0036 17.3 11.1 13.7 2 2 13 16 16 16 4 BRE1 E3 ubiquitin ligase IQ PF00612.27 KFP01407.1 - 0.0063 16.2 0.3 0.044 13.6 0.1 2.4 2 0 0 2 2 2 1 IQ calmodulin-binding motif TPR_MLP1_2 PF07926.12 KFP01407.1 - 0.0083 16.2 9.9 0.0083 16.2 9.9 12.2 2 2 9 12 12 12 3 TPR/MLP1/MLP2-like protein AAA_22 PF13401.6 KFP01407.1 - 0.086 13.1 0.0 0.086 13.1 0.0 5.4 3 2 2 5 5 5 0 AAA domain AAA_16 PF13191.6 KFP01407.1 - 0.6 10.5 0.0 0.6 10.5 0.0 5.7 2 1 0 2 2 2 0 AAA ATPase domain Myosin_head PF00063.21 KFP01410.1 - 4.7e-281 933.9 2.7 4.7e-281 933.9 2.7 3.0 4 1 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KFP01410.1 - 5.1e-111 372.3 226.1 7.6e-77 259.1 132.7 3.1 2 1 1 3 3 3 3 Myosin tail Myosin_N PF02736.19 KFP01410.1 - 1.3e-13 50.5 1.3 3.3e-13 49.2 1.3 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain DUF1664 PF07889.12 KFP01410.1 - 0.0036 17.3 9.3 0.0036 17.3 9.3 12.2 3 2 10 14 14 14 6 Protein of unknown function (DUF1664) BBP1_C PF15272.6 KFP01410.1 - 0.0045 16.8 15.7 0.0045 16.8 15.7 9.3 1 1 7 8 8 8 1 Spindle pole body component BBP1, C-terminal BRE1 PF08647.11 KFP01410.1 - 0.0071 16.4 12.1 0.0071 16.4 12.1 13.3 2 1 12 15 15 15 3 BRE1 E3 ubiquitin ligase IQ PF00612.27 KFP01410.1 - 0.03 14.1 0.8 0.099 12.5 0.2 2.2 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_22 PF13401.6 KFP01410.1 - 0.077 13.3 0.0 0.077 13.3 0.0 4.8 4 1 0 4 4 4 0 AAA domain Filament PF00038.21 KFP01410.1 - 0.41 10.2 189.3 0.024 14.2 10.5 7.1 1 1 5 6 6 6 0 Intermediate filament protein AAA_16 PF13191.6 KFP01410.1 - 0.67 10.3 0.0 0.67 10.3 0.0 5.3 2 1 0 3 3 3 0 AAA ATPase domain Myosin_head PF00063.21 KFP01413.1 - 9.2e-279 926.3 3.7 9.2e-279 926.3 3.7 3.1 4 0 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KFP01413.1 - 3e-155 518.8 264.0 3.6e-155 518.5 264.0 1.0 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 KFP01413.1 - 9.6e-14 50.9 2.2 2.8e-13 49.4 2.2 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Syntaxin-6_N PF09177.11 KFP01413.1 - 0.011 16.3 6.7 0.011 16.3 6.7 13.9 2 2 8 13 13 13 0 Syntaxin 6, N-terminal IQ PF00612.27 KFP01413.1 - 0.033 14.0 1.5 0.091 12.6 0.3 2.3 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_22 PF13401.6 KFP01413.1 - 0.085 13.1 0.0 0.085 13.1 0.0 5.2 3 2 1 4 4 4 0 AAA domain AAA_16 PF13191.6 KFP01413.1 - 0.68 10.3 0.0 0.68 10.3 0.0 6.3 3 2 0 4 4 4 0 AAA ATPase domain Myosin_head PF00063.21 KFP01415.1 - 2.5e-284 944.8 2.6 2.5e-284 944.8 2.6 3.1 3 1 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KFP01415.1 - 9.2e-135 450.9 253.7 1.2e-134 450.6 253.7 1.0 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 KFP01415.1 - 1.7e-11 43.7 1.0 5.9e-11 42.0 1.0 2.0 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 KFP01415.1 - 0.1 12.8 0.0 0.1 12.8 0.0 4.8 3 1 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KFP01415.1 - 0.72 10.2 0.0 0.72 10.2 0.0 4.6 4 2 0 4 4 4 0 AAA ATPase domain SCO1-SenC PF02630.14 KFP01417.1 - 4.5e-49 165.8 0.0 5.3e-49 165.6 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KFP01417.1 - 5.1e-07 29.6 0.0 7.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KFP01417.1 - 0.00029 21.1 0.0 0.0004 20.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like TMEM220 PF15071.6 KFP01418.1 - 1e-13 51.9 1.7 1.1e-13 51.8 0.5 1.6 2 0 0 2 2 2 1 Transmembrane family 220, helix RPEL PF02755.15 KFP01419.1 - 2.2e-18 65.3 6.7 9.9e-07 28.3 0.0 3.5 3 0 0 3 3 3 3 RPEL repeat SAP PF02037.27 KFP01419.1 - 5e-10 38.9 2.1 7.4e-10 38.4 0.1 2.3 2 0 0 2 2 2 1 SAP domain Lactamase_B_2 PF12706.7 KFP01420.1 - 2.4e-10 40.3 0.5 3.2e-09 36.6 0.5 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KFP01420.1 - 0.0016 18.5 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DASH_Ask1 PF08655.10 KFP01420.1 - 0.051 13.5 0.1 0.78 9.7 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Ask1 Shisa PF13908.6 KFP01422.1 - 9.5e-08 32.5 0.0 1e-07 32.4 0.0 1.0 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator PI3K_1B_p101 PF10486.9 KFP01423.1 - 5.7e-10 37.7 0.2 4e-08 31.6 0.2 2.2 1 1 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TnpW PF14202.6 KFP01423.1 - 0.017 14.9 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Transposon-encoded protein TnpW NTR PF01759.21 KFP01424.1 - 3.1e-05 23.7 0.0 4.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 UNC-6/NTR/C345C module zf-RING_UBOX PF13445.6 KFP01425.1 - 6.2e-11 42.1 8.0 6.7e-11 42.0 8.0 1.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFP01425.1 - 2.3e-09 37.3 8.2 2.5e-09 37.1 8.2 1.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KFP01425.1 - 1.5e-08 34.3 5.9 1.6e-08 34.2 5.9 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP01425.1 - 2.6e-08 33.6 5.7 2.7e-08 33.5 5.7 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP01425.1 - 1.1e-06 28.8 6.2 1.2e-06 28.7 6.2 1.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFP01425.1 - 3.4e-06 26.8 5.7 3.7e-06 26.7 5.7 1.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP01425.1 - 0.00015 21.7 7.1 0.00018 21.4 7.1 1.1 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP01425.1 - 0.0025 17.6 7.4 0.0034 17.2 7.4 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KFP01425.1 - 0.035 14.2 6.9 0.04 14.1 6.9 1.1 1 0 0 1 1 1 0 zinc RING finger of MSL2 U-box PF04564.15 KFP01425.1 - 0.1 12.8 0.0 0.11 12.7 0.0 1.0 1 0 0 1 1 1 0 U-box domain zf-RING_11 PF17123.5 KFP01425.1 - 0.14 11.9 8.4 0.3 10.9 8.4 1.6 1 1 0 1 1 1 0 RING-like zinc finger Peptidase_S10 PF00450.22 KFP01427.1 - 6.5e-87 292.6 1.0 7.3e-87 292.5 1.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase ACP_syn_III_C PF08541.10 KFP01427.1 - 0.019 15.1 0.0 0.048 13.8 0.0 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Hydrolase_4 PF12146.8 KFP01427.1 - 0.019 14.2 0.0 0.61 9.3 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 UPF0114 PF03350.16 KFP01427.1 - 0.069 13.4 0.0 0.23 11.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 bZIP_1 PF00170.21 KFP01428.1 - 4.2e-05 23.5 4.4 4.2e-05 23.5 4.4 6.0 3 1 3 6 6 6 2 bZIP transcription factor ZapB PF06005.12 KFP01428.1 - 0.0033 17.8 6.6 0.0033 17.8 6.6 5.1 4 2 1 5 5 4 2 Cell division protein ZapB Ax_dynein_light PF10211.9 KFP01428.1 - 0.0073 16.3 34.0 0.73 9.8 5.7 3.6 2 1 1 3 3 3 3 Axonemal dynein light chain bZIP_2 PF07716.15 KFP01428.1 - 0.0074 16.3 3.9 0.0074 16.3 3.9 5.5 5 1 0 5 5 4 1 Basic region leucine zipper Leu_zip PF15294.6 KFP01428.1 - 0.021 14.4 35.0 0.32 10.5 0.8 3.2 2 1 1 3 3 3 0 Leucine zipper HAP1_N PF04849.13 KFP01428.1 - 0.03 13.5 41.7 0.039 13.2 31.9 2.4 1 1 1 2 2 2 0 HAP1 N-terminal conserved region FlaC_arch PF05377.11 KFP01428.1 - 0.048 14.1 21.9 0.32 11.4 0.8 4.5 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Shugoshin_N PF07558.11 KFP01428.1 - 0.092 12.6 17.2 0.29 11.0 1.3 4.7 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region HALZ PF02183.18 KFP01428.1 - 0.19 11.9 20.7 2.4 8.5 1.8 4.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper CHDCT2 PF08074.11 KFP01428.1 - 0.46 10.6 10.8 0.15 12.2 5.7 2.6 3 0 0 3 3 2 0 CHDCT2 (NUC038) domain VGPC1_C PF16799.5 KFP01428.1 - 0.52 10.3 14.7 0.41 10.7 2.0 4.1 3 1 1 4 4 4 0 C-terminal membrane-localisation domain of ion-channel, VCN1 GCN5L1 PF06320.13 KFP01428.1 - 0.56 10.4 13.9 0.48 10.6 6.7 3.0 2 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) DivIC PF04977.15 KFP01428.1 - 0.72 9.7 33.2 0.029 14.1 2.7 5.1 3 2 2 6 6 6 0 Septum formation initiator MbeD_MobD PF04899.12 KFP01428.1 - 0.85 9.8 11.8 0.92 9.7 2.0 4.3 3 1 2 5 5 5 0 MbeD/MobD like PikAIV_N PF18605.1 KFP01428.1 - 1.8 8.2 10.1 0.37 10.4 0.8 3.4 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain NPV_P10 PF05531.12 KFP01428.1 - 2.1 8.9 15.2 1.2 9.6 2.2 3.8 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.7 KFP01428.1 - 6 7.0 45.1 19 5.4 31.6 3.5 1 1 0 2 2 2 0 Tropomyosin like Fmp27_WPPW PF10359.9 KFP01428.1 - 6.6 5.5 36.1 1.2 7.9 7.8 3.0 1 1 2 3 3 3 0 RNA pol II promoter Fmp27 protein domain Jnk-SapK_ap_N PF09744.9 KFP01428.1 - 7.6 6.7 46.0 9.3 6.5 25.0 3.3 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 DUF4988 PF16378.5 KFP01428.1 - 9.4 5.9 10.2 19 4.9 0.5 3.4 3 0 0 3 3 3 0 Domain of unknown function SlyX PF04102.12 KFP01428.1 - 10 6.9 32.6 3.5 8.3 5.4 5.5 5 1 1 6 6 5 0 SlyX U3_assoc_6 PF08640.11 KFP01429.1 - 7.5e-15 54.8 5.9 7.5e-15 54.8 5.9 3.0 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 KFP01429.1 - 0.00017 22.2 8.6 1.2 10.2 0.2 6.5 6 2 1 7 7 7 2 Tetratricopeptide repeat HMGL-like PF00682.19 KFP01429.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 HMGL-like VEFS-Box PF09733.9 KFP01430.1 - 1.4e-54 183.6 2.9 3.2e-54 182.5 2.9 1.6 1 0 0 1 1 1 1 VEFS-Box of polycomb protein DUF2070 PF09843.9 KFP01430.1 - 0.003 15.9 0.1 0.0042 15.4 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) AAA PF00004.29 KFP01431.1 - 8.3e-09 36.0 0.3 2.8e-06 27.8 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KFP01431.1 - 4.8e-06 26.6 2.5 0.046 13.6 0.0 3.3 2 1 1 3 3 3 2 Rad17 P-loop domain AAA_16 PF13191.6 KFP01431.1 - 0.00036 21.0 0.0 0.002 18.6 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KFP01431.1 - 0.0061 15.8 0.2 0.063 12.5 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 KFP01431.1 - 0.0064 16.8 0.4 0.044 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KFP01431.1 - 0.011 15.4 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 KFP01431.1 - 0.017 15.1 0.0 0.056 13.4 0.0 1.9 1 0 0 1 1 1 0 NTPase IstB_IS21 PF01695.17 KFP01431.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KFP01431.1 - 0.26 11.8 0.0 0.26 11.8 0.0 4.3 6 0 0 6 6 6 0 AAA domain ArfGap PF01412.18 KFP01432.1 - 1e-26 93.3 0.1 1.9e-26 92.4 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 KFP01432.1 - 1.3e-18 67.4 1.3 2.7e-08 34.3 0.1 2.8 2 1 0 2 2 2 2 PH domain PH_8 PF15409.6 KFP01432.1 - 3e-08 33.8 4.5 0.0019 18.5 0.1 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 KFP01432.1 - 1.9e-06 28.3 7.1 0.017 15.6 0.3 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.7 KFP01432.1 - 0.04 14.0 1.0 0.12 12.5 0.0 2.3 2 2 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.6 KFP01432.1 - 0.12 12.8 0.0 0.77 10.1 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain Rhomboid PF01694.22 KFP01433.1 - 5.8e-34 117.3 11.7 5.8e-34 117.3 11.7 1.9 2 0 0 2 2 2 1 Rhomboid family EF-hand_7 PF13499.6 KFP01433.1 - 3.2e-09 37.1 0.0 5.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KFP01433.1 - 7.1e-07 29.0 0.0 7.1e-05 22.6 0.0 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFP01433.1 - 1.3e-06 27.5 0.0 0.0086 15.6 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_11 PF08976.11 KFP01433.1 - 0.00032 21.5 0.0 0.00055 20.8 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain DUF5580 PF17743.1 KFP01433.1 - 0.00043 18.9 0.0 0.00054 18.6 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) EF-hand_6 PF13405.6 KFP01433.1 - 0.00088 19.0 0.1 0.056 13.4 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain DUF3087 PF11286.8 KFP01433.1 - 0.068 12.6 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) DUF4203 PF13886.6 KFP01433.1 - 2.6 7.7 16.8 2.7 7.6 3.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) ARL6IP6 PF15062.6 KFP01433.1 - 3.1 8.0 5.4 1.6 8.9 0.2 2.6 3 0 0 3 3 3 0 Haemopoietic lineage transmembrane helix Njmu-R1 PF15053.6 KFP01434.1 - 4.1e-169 562.2 6.0 1.3e-168 560.6 6.0 1.6 1 1 0 1 1 1 1 Mjmu-R1-like protein family zf-C2H2_4 PF13894.6 KFP01435.1 - 0.47 11.4 6.8 6.8 7.8 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-FCS PF06467.14 KFP01435.1 - 0.71 9.9 3.9 0.39 10.7 1.3 2.0 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif RNA_pol_Rpb2_2 PF04561.14 KFP01436.1 - 0.0021 17.7 0.6 0.0051 16.5 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 ANAPC3 PF12895.7 KFP01436.1 - 0.13 12.5 0.4 0.36 11.1 0.4 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KFP01436.1 - 0.44 11.1 3.3 0.2 12.2 0.4 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 KFP01437.1 - 2.5e-44 151.6 0.0 4.4e-44 150.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 KFP01437.1 - 1.1e-41 142.0 0.1 1.9e-41 141.2 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 KFP01437.1 - 4.4e-26 91.7 0.0 6.8e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.6 KFP01437.1 - 1e-07 31.8 0.0 0.0077 15.8 0.0 2.3 2 0 0 2 2 2 2 PQQ-like domain APH PF01636.23 KFP01437.1 - 6.8e-06 26.2 0.3 0.03 14.3 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family PQQ PF01011.21 KFP01437.1 - 7.7e-06 25.6 1.2 0.11 12.4 0.0 3.9 5 0 0 5 5 5 2 PQQ enzyme repeat Pkinase_fungal PF17667.1 KFP01437.1 - 1.5e-05 24.0 0.0 0.00012 21.0 0.0 1.8 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFP01437.1 - 0.00099 18.5 0.1 0.0019 17.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ_3 PF13570.6 KFP01437.1 - 1.1 9.8 3.5 5.5 7.6 0.0 3.9 4 2 1 5 5 5 0 PQQ-like domain Ig_2 PF13895.6 KFP01438.1 - 2.4e-41 140.0 5.3 4.6e-08 33.3 0.0 6.2 6 0 0 6 6 6 6 Immunoglobulin domain Ig_3 PF13927.6 KFP01438.1 - 2.7e-36 124.0 0.7 2.4e-05 24.8 0.0 6.9 7 0 0 7 7 7 6 Immunoglobulin domain ig PF00047.25 KFP01438.1 - 5.6e-21 74.5 10.4 0.002 18.2 0.0 7.6 6 3 0 6 6 6 5 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFP01438.1 - 2.4e-13 49.9 0.0 0.001 19.1 0.0 5.3 5 0 0 5 5 5 2 C17orf99 Ig domain I-set PF07679.16 KFP01438.1 - 1.1e-12 47.9 11.2 0.22 11.6 0.4 7.7 6 3 0 6 6 6 5 Immunoglobulin I-set domain V-set PF07686.17 KFP01438.1 - 5.3e-12 45.9 3.5 1.1 9.5 0.0 6.7 6 1 1 7 7 7 4 Immunoglobulin V-set domain Izumo-Ig PF16706.5 KFP01438.1 - 7.7e-08 32.3 2.2 0.82 9.8 0.1 5.3 5 1 0 5 5 5 2 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFP01438.1 - 1e-07 31.4 0.5 1.6 8.3 0.0 5.2 5 0 0 5 5 5 3 Immunoglobulin domain Ig_5 PF16681.5 KFP01438.1 - 2.2e-05 24.7 3.3 0.1 13.0 0.1 5.5 6 0 0 6 6 6 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set PF05790.15 KFP01438.1 - 0.0016 18.6 0.4 16 5.8 0.0 5.0 5 0 0 5 5 5 0 Immunoglobulin C2-set domain Ig_C19orf38 PF17737.1 KFP01438.1 - 0.0019 18.5 0.2 15 6.0 0.0 4.4 4 1 0 4 4 4 0 Ig domain in C19orf38 (HIDE1) ICAM_N PF03921.14 KFP01438.1 - 0.009 15.7 2.9 0.037 13.7 0.2 3.1 3 0 0 3 3 3 1 Intercellular adhesion molecule (ICAM), N-terminal domain Ig_Tie2_1 PF10430.9 KFP01438.1 - 0.019 15.4 0.1 0.18 12.2 0.0 2.6 2 0 0 2 2 2 0 Tie-2 Ig-like domain 1 DUF3108 PF11306.8 KFP01438.1 - 0.029 14.4 0.0 0.087 12.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3108) Ig_C17orf99 PF17736.1 KFP01439.1 - 2.6e-24 85.1 1.5 4.1e-13 49.2 0.1 2.2 2 0 0 2 2 2 2 C17orf99 Ig domain Ig_3 PF13927.6 KFP01439.1 - 1.1e-20 74.0 0.1 6.4e-09 36.3 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP01439.1 - 2.4e-18 66.3 1.6 1.6e-09 38.0 0.2 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP01439.1 - 3.9e-14 52.6 1.2 4.1e-06 26.9 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP01439.1 - 1.3e-09 38.0 0.0 0.00048 20.1 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 KFP01439.1 - 1.3e-06 28.6 4.4 0.42 10.8 0.0 4.1 2 2 2 4 4 4 3 Immunoglobulin V-set domain Ig_C19orf38 PF17737.1 KFP01439.1 - 5.6e-05 23.4 0.1 0.038 14.3 0.0 2.4 2 1 0 2 2 2 2 Ig domain in C19orf38 (HIDE1) C2-set_2 PF08205.12 KFP01439.1 - 0.00011 22.2 0.0 0.035 14.2 0.0 2.3 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain MBG_2 PF18676.1 KFP01439.1 - 0.0004 21.0 1.1 0.017 15.7 0.2 2.4 2 0 0 2 2 2 1 MBG domain (YGX type) ETRAMP PF09716.10 KFP01439.1 - 0.092 12.8 0.1 0.14 12.2 0.1 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) HGTP_anticodon PF03129.20 KFP01440.1 - 1.4e-10 41.2 0.0 2.2e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain DEAD PF00270.29 KFP01441.1 - 1.3e-48 165.1 0.0 7.4e-48 162.6 0.0 2.2 2 1 1 3 3 3 1 DEAD/DEAH box helicase P68HR PF08061.11 KFP01441.1 - 3.2e-28 97.5 19.9 8.3e-15 54.6 2.8 2.6 2 0 0 2 2 2 2 P68HR (NUC004) repeat Helicase_C PF00271.31 KFP01441.1 - 2.1e-26 92.4 0.1 8.8e-26 90.4 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP01441.1 - 0.00011 22.3 0.0 0.00097 19.2 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HECT PF00632.25 KFP01442.1 - 5.4e-103 344.7 0.0 7.3e-103 344.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KFP01442.1 - 5.6e-30 103.1 9.4 2.4e-11 43.5 0.2 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.30 KFP01442.1 - 7.1e-16 58.4 0.0 1.9e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain HPS3_N PF14761.6 KFP01442.1 - 0.051 13.1 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 Arm PF00514.23 KFP01443.1 - 9.2e-83 270.1 4.8 8.9e-11 41.5 0.0 8.6 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KFP01443.1 - 2.9e-30 104.6 6.6 8.7e-30 103.0 6.6 1.9 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 KFP01443.1 - 8.3e-25 86.1 2.8 1.5e-24 85.3 2.1 1.8 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 KFP01443.1 - 1.3e-19 70.3 0.1 8.4e-07 29.4 0.0 5.0 4 1 0 4 4 4 3 HEAT-like repeat HEAT_2 PF13646.6 KFP01443.1 - 1.2e-11 44.9 0.1 0.0067 16.8 0.0 5.3 3 2 3 6 6 6 3 HEAT repeats HEAT PF02985.22 KFP01443.1 - 2.6e-08 33.4 1.1 0.15 12.4 0.0 6.2 7 0 0 7 7 7 2 HEAT repeat KAP PF05804.12 KFP01443.1 - 0.00049 18.4 0.1 0.28 9.3 0.1 2.8 2 1 0 3 3 3 2 Kinesin-associated protein (KAP) UxaC PF02614.14 KFP01443.1 - 0.015 14.2 0.0 1.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Glucuronate isomerase SYCP2_ARLD PF18581.1 KFP01443.1 - 0.071 13.1 0.2 37 4.3 0.0 3.7 3 1 0 4 4 4 0 Synaptonemal complex 2 armadillo-repeat-like domain ECF-ribofla_trS PF07155.12 KFP01443.1 - 0.17 11.9 0.2 0.31 11.0 0.2 1.3 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component NTR PF01759.21 KFP01444.1 - 0.07 12.9 0.1 0.15 11.9 0.1 1.6 1 1 0 1 1 1 0 UNC-6/NTR/C345C module Bromodomain PF00439.25 KFP01445.1 - 1e-25 89.6 0.2 2.2e-25 88.5 0.2 1.6 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 KFP01445.1 - 4.8e-18 64.8 28.7 2e-09 37.2 7.1 3.1 2 0 0 2 2 2 2 PHD-finger DDT PF02791.17 KFP01445.1 - 4.7e-17 62.0 0.3 9.9e-17 61.0 0.3 1.6 1 0 0 1 1 1 1 DDT domain WSD PF15613.6 KFP01445.1 - 6e-09 36.3 1.3 6e-09 36.3 1.3 5.9 4 1 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 KFP01445.1 - 0.00021 20.8 0.0 0.00069 19.1 0.0 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 C1_1 PF00130.22 KFP01445.1 - 1.6 8.7 14.3 4.8 7.2 1.2 2.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NUC205 PF08168.11 KFP01446.1 - 1.2e-09 37.5 0.1 2.4e-09 36.5 0.1 1.6 1 0 0 1 1 1 1 NUC205 domain Utp12 PF04003.12 KFP01446.1 - 0.011 16.0 0.6 0.29 11.5 0.4 3.1 3 0 0 3 3 3 0 Dip2/Utp12 Family Gly_acyl_tr_N PF06021.11 KFP01446.1 - 0.044 13.9 0.3 0.74 9.9 0.0 2.4 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase HisG_C PF08029.11 KFP01446.1 - 0.14 12.3 0.0 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 HisG, C-terminal domain IP_trans PF02121.18 KFP01447.1 - 3.7e-94 314.9 2.5 4.3e-94 314.7 2.5 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein PCI PF01399.27 KFP01448.1 - 1.6e-23 83.2 1.2 7.2e-23 81.1 0.0 2.6 2 1 0 2 2 2 1 PCI domain RPN5_C PF18098.1 KFP01448.1 - 1.7e-15 56.8 8.4 3.6e-15 55.8 8.4 1.6 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain Tubulin_C PF03953.17 KFP01448.1 - 0.11 12.7 0.2 0.59 10.3 0.1 2.3 1 1 1 2 2 2 0 Tubulin C-terminal domain AAA_12 PF13087.6 KFP01449.1 - 1.3e-34 119.5 0.0 2.7e-34 118.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFP01449.1 - 1.3e-23 84.1 7.1 2.2e-12 47.3 0.1 3.3 2 1 1 3 3 2 2 AAA domain AAA_19 PF13245.6 KFP01449.1 - 5.1e-10 39.9 0.0 6.8e-08 33.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFP01449.1 - 7.3e-09 35.6 0.0 3.8e-08 33.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain zf-CCCH PF00642.24 KFP01449.1 - 7.3e-08 32.1 0.6 2e-07 30.8 0.6 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ResIII PF04851.15 KFP01449.1 - 1.8e-05 24.9 0.0 4.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KFP01449.1 - 2.4e-05 23.9 0.0 0.02 14.4 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein UvrD-helicase PF00580.21 KFP01449.1 - 0.00011 21.9 0.0 0.00011 21.9 0.0 2.8 4 0 0 4 4 4 1 UvrD/REP helicase N-terminal domain PAM2 PF07145.15 KFP01449.1 - 0.00022 20.7 0.1 0.00092 18.7 0.1 2.2 1 0 0 1 1 1 1 Ataxin-2 C-terminal region zf_CCCH_4 PF18345.1 KFP01449.1 - 0.0011 18.9 1.2 0.0029 17.6 1.2 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KFP01449.1 - 0.0055 16.5 0.3 0.014 15.2 0.3 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger AAA_7 PF12775.7 KFP01449.1 - 0.024 14.2 0.0 0.072 12.6 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Helicase_RecD PF05127.14 KFP01449.1 - 0.039 13.8 0.1 0.24 11.2 0.0 2.4 2 0 0 2 2 2 0 Helicase AAA_14 PF13173.6 KFP01449.1 - 0.04 14.0 0.0 1.8 8.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KFP01449.1 - 0.045 14.0 0.0 0.18 12.1 0.0 2.2 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 KFP01449.1 - 0.072 12.9 0.3 0.31 10.8 0.0 2.1 3 0 0 3 3 3 0 Bacterial dnaA protein AAA_16 PF13191.6 KFP01449.1 - 0.085 13.2 0.0 0.5 10.7 0.0 2.3 2 0 0 2 2 1 0 AAA ATPase domain AAA_5 PF07728.14 KFP01449.1 - 0.16 11.9 0.1 0.63 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Claudin_2 PF13903.6 KFP01450.1 - 4.2e-36 124.5 3.8 5.1e-36 124.2 3.8 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFP01450.1 - 2.1e-14 53.8 7.6 4.4e-08 33.2 3.8 2.1 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family Clc-like PF07062.12 KFP01450.1 - 0.018 14.5 3.2 0.044 13.3 3.2 1.7 1 1 0 1 1 1 0 Clc-like HisKA_7TM PF16927.5 KFP01450.1 - 0.019 15.0 3.5 0.028 14.5 1.1 1.9 2 0 0 2 2 2 0 N-terminal 7TM region of histidine kinase DUF805 PF05656.14 KFP01450.1 - 0.24 11.8 2.7 0.18 12.2 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF805) LapA_dom PF06305.11 KFP01450.1 - 0.9 9.4 8.8 3.8 7.4 0.1 2.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF2207 PF09972.9 KFP01450.1 - 1 8.0 3.6 0.25 10.1 0.6 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) PMP22_Claudin PF00822.20 KFP01451.1 - 1.5e-24 86.7 0.0 2.7e-24 85.9 0.0 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP01451.1 - 3.4e-10 40.0 0.0 5e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction AA_permease_2 PF13520.6 KFP01451.1 - 0.0034 16.3 0.1 0.0046 15.9 0.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2269 PF10027.9 KFP01451.1 - 0.034 14.2 0.0 0.055 13.5 0.0 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) Yae1_N PF09811.9 KFP01452.1 - 5e-11 42.1 32.0 70 3.3 32.0 3.3 1 1 0 1 1 1 1 Essential protein Yae1, N terminal Claudin_2 PF13903.6 KFP01453.1 - 1.6e-21 76.9 2.4 2.3e-21 76.4 2.4 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFP01453.1 - 2e-21 76.6 3.9 4.5e-21 75.4 3.9 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF716 PF04819.12 KFP01453.1 - 0.023 14.3 0.2 0.041 13.5 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF716) Claudin_3 PF06653.11 KFP01453.1 - 0.69 9.8 10.9 7.3 6.5 11.0 1.9 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DHHC PF01529.20 KFP01453.1 - 1.6 8.8 8.1 0.12 12.5 2.0 2.0 1 1 1 2 2 2 0 DHHC palmitoyltransferase Tetraspanin PF00335.20 KFP01453.1 - 2 8.1 7.7 2.5 7.7 1.8 2.4 2 1 1 3 3 3 0 Tetraspanin family MFS_1 PF07690.16 KFP01453.1 - 2.8 6.8 15.0 18 4.2 14.0 1.9 1 1 1 2 2 2 0 Major Facilitator Superfamily DUF4199 PF13858.6 KFP01453.1 - 3.9 7.9 10.8 6.6 7.1 10.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) C2 PF00168.30 KFP01454.1 - 2.1e-29 101.9 0.1 3.4e-29 101.2 0.1 1.4 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.25 KFP01454.1 - 2.5e-21 76.3 0.0 1.9e-13 50.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain C1_1 PF00130.22 KFP01454.1 - 5e-18 64.7 15.9 2e-16 59.6 4.8 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_Tyr PF07714.17 KFP01454.1 - 3.1e-09 36.5 0.0 2e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KFP01454.1 - 0.00031 21.4 0.6 0.00088 19.9 0.6 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Sushi PF00084.20 KFP01455.1 - 1.2e-41 141.1 21.6 7.1e-11 42.5 0.4 5.1 5 0 0 5 5 5 4 Sushi repeat (SCR repeat) Sushi_2 PF09014.10 KFP01455.1 - 3.6e-28 97.3 1.2 3.6e-28 97.3 1.2 2.4 3 0 0 3 3 3 1 Beta-2-glycoprotein-1 fifth domain HRM PF02793.22 KFP01455.1 - 0.00034 20.8 13.3 1.5 9.2 0.1 4.6 4 0 0 4 4 4 4 Hormone receptor domain Meleagrin PF08189.11 KFP01455.1 - 0.53 10.0 13.5 0.31 10.8 1.6 3.9 4 0 0 4 4 4 0 Meleagrin/Cygnin family Tup_N PF08581.10 KFP01456.1 - 0.023 15.0 10.9 0.023 15.0 10.9 9.6 4 3 4 9 9 9 0 Tup N-terminal DUF5131 PF07505.11 KFP01456.1 - 6.7 6.1 12.1 0.23 10.9 4.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5131) RGS_DHEX PF18148.1 KFP01457.1 - 3.2e-45 152.3 1.6 7.3e-45 151.2 1.6 1.6 1 0 0 1 1 1 1 Regulator of G-protein signalling DHEX domain RGS PF00615.19 KFP01457.1 - 7.1e-32 110.2 0.0 1.4e-31 109.2 0.0 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain G-gamma PF00631.22 KFP01457.1 - 2.6e-10 40.2 0.0 1.1e-09 38.1 0.0 2.0 2 0 0 2 2 2 1 GGL domain DEP PF00610.21 KFP01457.1 - 1e-08 35.1 0.1 4.2e-08 33.1 0.0 2.2 3 0 0 3 3 3 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-alpha PF00503.20 KFP01458.1 - 1.7e-108 362.9 2.0 2e-108 362.7 2.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFP01458.1 - 2.7e-17 62.8 2.2 5.1e-13 48.8 0.2 3.4 3 1 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFP01458.1 - 0.00037 19.9 3.8 0.003 16.9 0.4 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KFP01458.1 - 0.0043 17.3 0.6 3.5 7.9 0.1 3.3 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KFP01458.1 - 0.0047 17.0 0.0 1.1 9.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP01458.1 - 0.015 14.8 0.1 1 8.8 0.1 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 KFP01458.1 - 0.017 14.5 0.0 0.23 10.8 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Ras PF00071.22 KFP01458.1 - 0.053 13.1 0.4 5.6 6.5 0.0 2.7 2 1 0 2 2 2 0 Ras family MFS_1 PF07690.16 KFP01459.1 - 3.8e-38 131.3 19.2 3.6e-36 124.8 15.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP01459.1 - 0.0017 17.3 29.2 0.019 13.9 10.8 2.7 2 2 0 2 2 2 2 Sugar (and other) transporter SUIM_assoc PF16619.5 KFP01459.1 - 0.046 13.8 0.0 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 MFS_1_like PF12832.7 KFP01459.1 - 0.87 8.4 21.6 0.18 10.6 5.8 3.4 3 1 0 3 3 3 0 MFS_1 like family Sulfatase PF00884.23 KFP01460.1 - 1.8e-67 227.9 0.0 2.5e-67 227.4 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KFP01460.1 - 2.1e-22 80.2 0.0 3.9e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 KFP01460.1 - 0.0038 16.9 0.0 0.009 15.6 0.0 1.6 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase WD40 PF00400.32 KFP01461.1 - 0.0022 18.8 0.0 16 6.6 0.0 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP01461.1 - 0.0064 16.8 0.0 4.2 7.8 0.0 3.7 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain BCAS3 PF12490.8 KFP01461.1 - 0.032 13.8 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 Fam20C PF06702.12 KFP01462.1 - 2.5e-75 253.0 0.6 4.6e-74 248.9 0.6 2.1 1 1 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 FAM198 PF15051.6 KFP01462.1 - 0.00078 18.4 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 FAM198 protein ABC_tran PF00005.27 KFP01463.1 - 4.8e-60 202.0 0.2 2.9e-31 108.8 0.3 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KFP01463.1 - 3.9e-33 115.0 43.7 3.8e-24 85.4 23.0 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KFP01463.1 - 4.1e-22 79.4 4.1 2.4e-08 34.1 0.1 5.2 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFP01463.1 - 8.4e-10 38.8 3.2 0.00014 21.8 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KFP01463.1 - 1.6e-05 24.6 3.0 0.017 14.8 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 KFP01463.1 - 4.1e-05 23.1 1.8 0.033 13.6 0.1 3.9 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KFP01463.1 - 0.00095 18.9 0.1 1.4 8.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KFP01463.1 - 0.0013 18.8 0.5 1 9.5 0.1 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KFP01463.1 - 0.0021 17.8 0.7 2.6 7.7 0.0 3.8 3 2 1 4 4 4 1 AAA ATPase domain Rad17 PF03215.15 KFP01463.1 - 0.0028 17.6 2.2 0.58 10.1 0.5 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_22 PF13401.6 KFP01463.1 - 0.004 17.4 0.8 1.1 9.6 0.3 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFP01463.1 - 0.0042 17.5 0.2 0.21 12.0 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 KFP01463.1 - 0.0047 16.7 0.3 3.3 7.4 0.0 3.5 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_33 PF13671.6 KFP01463.1 - 0.03 14.5 0.9 10 6.3 0.2 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KFP01463.1 - 0.053 13.1 1.1 1.8 8.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KFP01463.1 - 0.061 13.0 1.0 3.9 7.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KFP01463.1 - 0.13 12.7 0.4 50 4.3 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KFP01463.1 - 0.66 10.4 16.6 0.16 12.4 1.2 3.2 3 2 0 3 3 2 0 AAA domain TsaE PF02367.17 KFP01463.1 - 0.77 9.8 4.5 5.2 7.1 0.2 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KFP01463.1 - 1.3 8.6 3.6 2.8 7.5 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 KFP01463.1 - 1.7 8.7 4.5 1.4 9.0 0.0 2.7 3 0 0 3 3 3 0 Dynamin family ABC_tran PF00005.27 KFP01464.1 - 1.6e-07 31.9 0.0 2.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFP01464.1 - 1.6e-07 31.4 0.0 3.2e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KFP01466.1 - 4.5e-05 22.7 9.9 5.4e-05 22.5 9.9 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 KFP01466.1 - 7.3e-05 23.3 0.2 0.0001 22.8 0.2 1.2 1 0 0 1 1 1 1 ABC transporter OpgC_C PF10129.9 KFP01466.1 - 0.018 13.9 0.8 0.022 13.7 0.8 1.1 1 0 0 1 1 1 0 OpgC protein AAA_29 PF13555.6 KFP01466.1 - 0.045 13.5 0.3 0.077 12.8 0.3 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFP01466.1 - 0.062 13.2 0.1 0.082 12.8 0.1 1.2 1 0 0 1 1 1 0 RsgA GTPase ABC2_membrane_3 PF12698.7 KFP01467.1 - 1.4e-08 34.3 0.4 1.4e-08 34.3 0.4 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 KFP01468.1 - 9.3e-59 197.8 0.0 7.6e-28 97.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KFP01468.1 - 7.7e-38 130.5 56.8 6.9e-28 97.7 22.2 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KFP01468.1 - 4.4e-15 56.3 0.0 0.00047 20.1 0.0 4.5 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFP01468.1 - 4.6e-10 39.7 0.2 0.00087 19.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KFP01468.1 - 1.1e-06 28.3 0.4 0.065 13.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KFP01468.1 - 7.8e-06 26.4 0.0 0.062 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KFP01468.1 - 1.3e-05 25.2 0.2 0.1 12.6 0.1 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_23 PF13476.6 KFP01468.1 - 7.9e-05 23.2 8.6 0.056 14.0 0.2 3.4 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KFP01468.1 - 0.00047 20.4 0.6 1.4 9.2 0.2 3.1 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KFP01468.1 - 0.0011 18.7 0.3 2.3 7.8 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.22 KFP01468.1 - 0.0022 17.2 0.5 16 4.6 0.0 3.2 3 0 0 3 3 3 0 NB-ARC domain SMC_N PF02463.19 KFP01468.1 - 0.0024 17.4 0.2 4.8 6.6 0.1 3.8 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KFP01468.1 - 0.0024 17.6 0.1 2 8.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KFP01468.1 - 0.0035 17.1 0.0 1.6 8.4 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_5 PF07728.14 KFP01468.1 - 0.0038 17.2 0.5 0.84 9.6 0.0 3.8 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 KFP01468.1 - 0.0071 16.4 0.0 0.12 12.5 0.0 2.6 2 1 0 2 2 2 1 Dynamin family AAA PF00004.29 KFP01468.1 - 0.0074 16.7 0.0 4.2 7.8 0.0 3.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KFP01468.1 - 0.0079 16.6 0.1 4.7 7.6 0.0 2.8 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.15 KFP01468.1 - 0.0088 16.0 0.7 0.47 10.4 0.0 3.1 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_33 PF13671.6 KFP01468.1 - 0.01 16.0 0.4 12 6.1 0.1 3.1 2 1 1 3 3 3 0 AAA domain cobW PF02492.19 KFP01468.1 - 0.011 15.3 1.6 0.78 9.3 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 KFP01468.1 - 0.023 14.4 0.1 5.2 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KFP01468.1 - 0.027 14.5 0.7 9.5 6.2 0.1 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF4162 PF13732.6 KFP01468.1 - 0.031 15.0 0.2 0.82 10.4 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_7 PF12775.7 KFP01468.1 - 0.038 13.5 0.2 4.8 6.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 KFP01468.1 - 0.048 12.7 0.1 1.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_25 PF13481.6 KFP01468.1 - 0.061 12.9 0.2 4.5 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KFP01468.1 - 0.071 13.0 1.2 14 5.6 0.3 3.3 3 0 0 3 3 3 0 NACHT domain Roc PF08477.13 KFP01468.1 - 0.095 12.9 0.2 27 5.0 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 KFP01468.1 - 0.1 11.9 1.2 9.5 5.4 0.0 3.1 3 0 0 3 3 3 0 Septin ATP-synt_ab PF00006.25 KFP01468.1 - 0.13 11.9 0.0 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Mg_chelatase PF01078.21 KFP01468.1 - 0.18 11.2 0.1 19 4.6 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI FeoB_N PF02421.18 KFP01468.1 - 0.24 10.9 0.8 8.4 5.9 0.1 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_28 PF13521.6 KFP01468.1 - 0.43 10.8 1.2 27 5.0 0.2 2.5 2 0 0 2 2 2 0 AAA domain CARM1 PF11531.8 KFP01468.1 - 0.65 10.2 3.8 1.8 8.8 0.2 3.2 3 0 0 3 3 2 0 Coactivator-associated arginine methyltransferase 1 N terminal Pkinase PF00069.25 KFP01469.1 - 1.1e-47 162.6 0.0 1.2e-47 162.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP01469.1 - 1.8e-32 112.6 0.0 2.1e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP01469.1 - 0.00073 18.9 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFP01469.1 - 0.001 18.1 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KFP01469.1 - 0.0032 16.6 0.2 0.0046 16.0 0.2 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 KFP01469.1 - 0.0035 16.2 0.1 0.0085 14.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFP01469.1 - 0.011 15.7 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFP01469.1 - 0.012 15.2 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase CLP1_P PF16575.5 KFP01469.1 - 0.045 13.5 0.1 0.092 12.5 0.1 1.5 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF4344 PF14247.6 KFP01469.1 - 0.073 12.7 0.0 0.095 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase PIP49_C PF12260.8 KFP01469.1 - 0.12 11.9 0.0 0.27 10.9 0.0 1.5 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 IRK_C PF17655.1 KFP01472.1 - 2.8e-62 209.4 0.0 4.1e-62 208.9 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFP01472.1 - 1.5e-57 193.4 6.5 2.3e-57 192.8 6.5 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 KFP01472.1 - 0.0027 17.6 5.4 0.0053 16.7 5.0 1.8 1 1 0 1 1 1 1 Ion channel IRK_C PF17655.1 KFP01473.1 - 4.8e-77 257.5 0.0 6.9e-77 257.0 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFP01473.1 - 1.4e-64 216.1 6.3 2.1e-64 215.6 6.3 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain IRK_N PF08466.10 KFP01473.1 - 2.4e-26 91.6 1.0 6e-26 90.3 1.0 1.7 1 0 0 1 1 1 1 Inward rectifier potassium channel N-terminal Ion_trans PF00520.31 KFP01473.1 - 0.0026 17.1 4.3 0.0037 16.5 4.3 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFP01473.1 - 0.0076 16.2 8.9 0.02 14.8 8.9 1.8 1 1 0 1 1 1 1 Ion channel FAM209 PF15206.6 KFP01473.1 - 0.18 11.6 0.2 0.47 10.2 0.2 1.7 1 1 0 1 1 1 0 FAM209 family Sox_N PF12444.8 KFP01474.1 - 3.3e-26 92.2 0.3 3.3e-26 92.2 0.3 3.2 3 2 0 3 3 3 1 Sox developmental protein N terminal HMG_box PF00505.19 KFP01474.1 - 6.8e-26 90.5 1.3 1.6e-25 89.3 1.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP01474.1 - 1e-10 42.1 1.1 1.9e-10 41.2 1.1 1.5 1 0 0 1 1 1 1 HMG-box domain VIT_2 PF13757.6 KFP01474.1 - 0.048 13.5 0.4 0.096 12.6 0.4 1.4 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain Zip PF02535.22 KFP01475.1 - 2.5e-22 79.6 10.5 9.4e-22 77.7 10.5 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter 7tm_1 PF00001.21 KFP01476.1 - 1.5e-65 221.2 20.0 1.8e-65 220.9 20.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP01476.1 - 7.5e-17 61.6 21.5 9.3e-17 61.3 21.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP01476.1 - 1.9e-14 53.9 12.8 1.9e-14 53.9 12.8 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFP01476.1 - 2.1e-11 43.7 8.5 2.1e-11 43.7 8.5 2.1 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv FA_desaturase PF00487.24 KFP01476.1 - 4 7.2 8.6 3.8 7.3 3.0 2.7 1 1 1 2 2 2 0 Fatty acid desaturase DUF3510 PF12022.8 KFP01477.1 - 0.14 12.5 0.1 0.98 9.8 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) FAM104 PF15434.6 KFP01478.1 - 4.3e-46 156.0 14.2 1.6e-45 154.1 14.2 1.7 1 1 0 1 1 1 1 Family 104 CDK2AP PF09806.9 KFP01478.1 - 0.23 11.5 4.9 0.27 11.3 4.9 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein SR-25 PF10500.9 KFP01478.1 - 4.8 6.7 22.6 2.6 7.6 21.0 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 KFP01478.1 - 7.9 4.9 8.2 8.1 4.9 8.2 1.0 1 0 0 1 1 1 0 Macoilin family WRW PF10206.9 KFP01479.1 - 5.4e-06 26.7 0.0 5.7e-06 26.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f BORG_CEP PF14957.6 KFP01480.1 - 2e-23 83.9 0.4 4.5e-23 82.7 0.4 1.6 1 0 0 1 1 1 1 Cdc42 effector PBD PF00786.28 KFP01480.1 - 8.8e-09 35.6 0.0 3.4e-08 33.7 0.0 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain fn3 PF00041.21 KFP01481.1 - 2.2e-174 566.3 35.6 4.9e-15 55.6 0.2 14.0 14 0 0 14 14 14 13 Fibronectin type III domain Ig_3 PF13927.6 KFP01481.1 - 9.6e-68 224.8 0.0 2.5e-13 50.4 0.0 7.1 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 KFP01481.1 - 1.6e-67 223.6 0.0 5.4e-15 55.2 0.0 7.3 7 0 0 7 7 7 6 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP01481.1 - 6.1e-50 167.5 0.0 7.1e-10 39.1 0.0 6.5 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.25 KFP01481.1 - 1.9e-36 124.1 0.0 4.3e-10 39.6 0.0 7.0 6 1 0 6 6 6 5 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFP01481.1 - 5.9e-29 100.5 12.2 0.0057 17.2 0.0 13.8 13 0 0 13 13 13 5 Purple acid Phosphatase, N-terminal domain V-set PF07686.17 KFP01481.1 - 2.2e-21 76.0 0.8 0.00071 19.7 0.0 9.8 6 5 1 7 7 7 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP01481.1 - 4.5e-12 45.9 0.1 0.81 9.8 0.0 6.2 6 0 0 6 6 6 3 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFP01481.1 - 9.7e-10 38.7 0.0 0.16 12.4 0.0 5.4 5 0 0 5 5 5 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFP01481.1 - 2.8e-08 33.2 0.0 0.24 11.0 0.0 5.7 5 0 0 5 5 5 1 Immunoglobulin domain Interfer-bind PF09294.10 KFP01481.1 - 7.9e-08 32.6 0.0 0.53 10.6 0.0 6.5 7 0 0 7 7 7 2 Interferon-alpha/beta receptor, fibronectin type III Ig_C17orf99 PF17736.1 KFP01481.1 - 0.0017 18.3 0.0 14 5.8 0.0 4.3 4 0 0 4 4 4 0 C17orf99 Ig domain GPI-anchored PF10342.9 KFP01481.1 - 0.0018 19.0 5.7 2.4 9.0 0.0 7.4 8 1 1 9 9 8 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family C1-set PF07654.15 KFP01481.1 - 0.0028 18.0 0.0 2 8.9 0.0 4.6 5 0 0 5 5 5 1 Immunoglobulin C1-set domain fn3_4 PF16794.5 KFP01481.1 - 0.21 11.5 0.3 13 5.8 0.0 4.1 4 0 0 4 4 4 0 Fibronectin-III type domain Y_Y_Y PF07495.13 KFP01481.1 - 0.67 9.9 2.2 7.8 6.5 0.0 3.7 5 0 0 5 5 4 0 Y_Y_Y domain Ribosomal_L38e PF01781.18 KFP01482.1 - 2.9e-24 84.9 1.7 3e-24 84.9 1.7 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Tweety PF04906.13 KFP01483.1 - 2.2e-122 408.7 7.4 2.5e-122 408.5 7.4 1.0 1 0 0 1 1 1 1 Tweety PAP2_3 PF14378.6 KFP01483.1 - 0.0075 16.0 1.5 0.15 11.7 1.8 2.1 2 0 0 2 2 2 1 PAP2 superfamily Glucos_trans_II PF14264.6 KFP01483.1 - 0.017 14.5 1.9 0.017 14.5 1.9 1.9 2 0 0 2 2 2 0 Glucosyl transferase GtrII DUF4131 PF13567.6 KFP01483.1 - 4.2 7.0 8.6 3.4 7.3 5.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Tetraspanin PF00335.20 KFP01483.1 - 4.5 6.9 16.8 0.088 12.5 9.0 2.0 1 1 1 2 2 2 0 Tetraspanin family ANAPC4_WD40 PF12894.7 KFP01484.1 - 0.0027 18.0 0.0 9.6 6.6 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFP01484.1 - 0.081 13.8 7.2 65 4.6 0.0 5.2 5 0 0 5 5 5 0 WD domain, G-beta repeat Oxidored-like PF09791.9 KFP01486.1 - 1.8e-06 27.5 6.1 2.5e-06 27.0 6.1 1.2 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF5522 PF17653.1 KFP01486.1 - 0.058 13.4 2.8 0.11 12.5 2.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5522) TAL_effector PF03377.13 KFP01486.1 - 0.17 12.2 0.1 0.29 11.5 0.1 1.4 1 0 0 1 1 1 0 TAL effector repeat PDE6_gamma PF04868.12 KFP01487.1 - 4.7e-49 164.6 0.3 5.3e-49 164.4 0.3 1.0 1 0 0 1 1 1 1 Retinal cGMP phosphodiesterase, gamma subunit NPL4 PF05021.15 KFP01488.1 - 4.9e-96 321.7 0.4 9.9e-93 310.8 0.0 2.3 2 0 0 2 2 2 2 NPL4 family zf-NPL4 PF05020.15 KFP01488.1 - 2.5e-62 209.3 0.2 4.2e-62 208.6 0.2 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 KFP01488.1 - 8.9e-31 106.2 0.1 1.6e-30 105.4 0.1 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 FANCAA PF15146.6 KFP01489.1 - 4.1e-126 421.6 0.7 4.7e-126 421.4 0.7 1.0 1 0 0 1 1 1 1 Fanconi anemia-associated FANCAA PF15146.6 KFP01490.1 - 2.4e-44 152.1 0.8 2.7e-44 152.0 0.8 1.0 1 0 0 1 1 1 1 Fanconi anemia-associated Actin PF00022.19 KFP01491.1 - 8.2e-134 446.2 0.0 2.9e-133 444.4 0.0 1.7 1 1 0 1 1 1 1 Actin ENTH PF01417.20 KFP01495.1 - 2.7e-06 27.5 0.0 7e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 ENTH domain IQ PF00612.27 KFP01496.1 - 0.0053 16.4 3.6 0.025 14.3 3.6 2.3 1 0 0 1 1 1 1 IQ calmodulin-binding motif HEAT_EZ PF13513.6 KFP01496.1 - 0.11 13.0 1.1 0.63 10.6 1.1 2.4 1 0 0 1 1 1 0 HEAT-like repeat Adeno_E3_14_5 PF04834.12 KFP01497.1 - 0.046 14.3 1.0 0.053 14.1 1.0 1.1 1 0 0 1 1 1 0 Early E3 14.5 kDa protein IMD PF08397.11 KFP01498.1 - 3.6e-96 320.8 7.5 5.1e-96 320.3 7.5 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain SH3_9 PF14604.6 KFP01498.1 - 3.1e-10 39.8 0.0 5.5e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP01498.1 - 1.2e-07 31.3 0.0 2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP01498.1 - 3.6e-05 23.3 0.0 6.5e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain BAR PF03114.18 KFP01498.1 - 0.0038 16.9 9.6 0.0069 16.1 9.6 1.5 1 1 0 1 1 1 1 BAR domain Peptidase_Mx1 PF15890.5 KFP01498.1 - 0.013 15.0 0.8 0.021 14.3 0.8 1.4 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase BAR_3 PF16746.5 KFP01498.1 - 0.087 12.5 11.2 0.16 11.6 11.2 1.5 1 1 0 1 1 1 0 BAR domain of APPL family DUF445 PF04286.12 KFP01498.1 - 0.21 11.4 1.7 0.27 11.0 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) AAA_lid_9 PF17871.1 KFP01498.1 - 0.97 9.4 4.2 20 5.2 0.0 2.8 2 1 1 3 3 3 0 AAA lid domain RasGAP PF00616.19 KFP01498.1 - 1.5 8.4 8.9 2.6 7.7 8.7 1.7 1 1 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase Exonuc_VII_L PF02601.15 KFP01498.1 - 2.6 7.5 6.8 3.9 7.0 6.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.14 KFP01498.1 - 3.4 8.0 14.7 1.5 9.1 8.3 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Snf7 PF03357.21 KFP01499.1 - 9.8e-38 129.4 15.9 1.1e-37 129.3 15.9 1.0 1 0 0 1 1 1 1 Snf7 Raptor_N PF14538.6 KFP01500.1 - 3.7e-73 244.3 0.0 7.4e-73 243.3 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 KFP01500.1 - 5.5e-14 51.1 2.7 0.00053 20.0 0.0 6.0 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 KFP01500.1 - 4.1e-10 39.9 0.0 4.7e-06 26.9 0.0 3.9 3 1 1 4 4 4 2 HEAT repeats WD40 PF00400.32 KFP01500.1 - 2.1e-07 31.5 11.3 0.081 13.8 0.2 7.2 7 0 0 7 7 7 2 WD domain, G-beta repeat Cnd1 PF12717.7 KFP01500.1 - 3.1e-07 30.6 0.0 0.00031 20.8 0.0 3.5 2 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KFP01500.1 - 3.5e-05 24.2 0.2 1.3 9.6 0.0 3.9 3 0 0 3 3 3 2 HEAT-like repeat Endonuc_BglI PF14562.6 KFP01500.1 - 0.01 15.0 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease BglI Hyccin PF09790.9 KFP01500.1 - 0.039 13.0 0.1 0.062 12.4 0.1 1.3 1 0 0 1 1 1 0 Hyccin ANAPC4_WD40 PF12894.7 KFP01500.1 - 0.096 13.0 0.0 34 4.8 0.0 3.1 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Pentaxin PF00354.17 KFP01501.1 - 4.5e-33 114.6 0.0 6.8e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.6 KFP01501.1 - 9.7e-16 58.3 0.0 1.4e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Pox_A_type_inc PF04508.12 KFP01501.1 - 0.0053 16.6 0.3 6.9 6.7 0.0 3.1 2 0 0 2 2 2 2 Viral A-type inclusion protein repeat Laminin_G_2 PF02210.24 KFP01501.1 - 0.012 16.2 0.0 0.022 15.4 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain DUF3024 PF11225.8 KFP01501.1 - 0.055 13.7 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3024) zf-ZPR1 PF03367.13 KFP01501.1 - 0.1 12.4 0.3 0.1 12.4 0.3 1.6 2 0 0 2 2 2 0 ZPR1 zinc-finger domain Pinin_SDK_N PF04697.13 KFP01501.1 - 0.15 12.7 1.5 0.25 12.0 1.5 1.3 1 0 0 1 1 1 0 pinin/SDK conserved region DUF848 PF05852.11 KFP01501.1 - 0.29 11.2 6.3 0.082 13.0 1.5 2.0 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF16 PF01519.16 KFP01501.1 - 0.31 11.5 8.1 0.98 9.9 1.1 2.8 2 1 0 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.12 KFP01501.1 - 0.67 10.6 11.3 0.54 10.9 0.4 3.9 2 1 2 4 4 4 0 SlyX Spc7 PF08317.11 KFP01501.1 - 2.5 6.9 11.2 0.26 10.1 2.8 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein CLZ PF16526.5 KFP01501.1 - 5.1 7.5 11.1 3.2 8.2 1.4 3.1 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FliJ PF02050.16 KFP01501.1 - 5.2 7.3 6.4 8.6 6.6 1.1 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein Endonuclease_5 PF04493.14 KFP01502.1 - 8.4e-64 214.9 0.0 1.1e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V Sulfatase PF00884.23 KFP01504.1 - 5.7e-50 170.5 0.0 1.4e-49 169.2 0.0 1.6 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFP01504.1 - 1.9e-09 37.6 0.0 6e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KFP01504.1 - 3e-09 37.1 0.9 5.9e-08 32.9 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 KFP01504.1 - 0.0094 16.7 0.6 0.021 15.6 0.6 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF1501 PF07394.12 KFP01504.1 - 0.11 11.6 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Glyco_hydro_31 PF01055.26 KFP01505.1 - 2.9e-140 468.4 0.0 2.3e-139 465.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KFP01505.1 - 8.6e-13 48.5 0.0 1.4e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KFP01505.1 - 6.2e-11 42.5 0.0 1.6e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 KFP01505.1 - 0.051 13.9 0.0 0.15 12.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5110) BRE1 PF08647.11 KFP01506.1 - 1.1e-21 76.7 18.1 1.1e-21 76.7 18.1 12.0 6 4 4 11 11 11 2 BRE1 E3 ubiquitin ligase CBX7_C PF17218.3 KFP01507.1 - 5.1e-13 48.5 0.8 1.3e-12 47.2 0.8 1.7 1 0 0 1 1 1 1 CBX family C-terminal motif CBX7_C PF17218.3 KFP01508.1 - 4.5e-15 55.1 2.3 7.5e-15 54.4 2.3 1.4 1 0 0 1 1 1 1 CBX family C-terminal motif Chromo PF00385.24 KFP01508.1 - 2.7e-12 46.4 0.5 2.7e-12 46.4 0.5 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RBR PF17208.3 KFP01508.1 - 2e-05 25.2 5.4 0.057 14.1 2.3 2.7 2 0 0 2 2 2 2 RNA binding Region VirC1 PF07015.11 KFP01508.1 - 0.21 10.8 0.2 0.34 10.2 0.2 1.2 1 0 0 1 1 1 0 VirC1 protein CBX7_C PF17218.3 KFP01509.1 - 1.9e-13 49.9 1.9 2.9e-13 49.3 1.9 1.3 1 0 0 1 1 1 1 CBX family C-terminal motif Fox-1_C PF12414.8 KFP01510.1 - 2.9e-41 139.8 16.2 1e-40 138.0 16.2 1.9 1 0 0 1 1 1 1 Calcitonin gene-related peptide regulator C terminal RRM_1 PF00076.22 KFP01510.1 - 8.2e-19 67.2 1.2 1.2e-18 66.7 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP01510.1 - 0.051 13.2 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_85 PF03644.13 KFP01511.1 - 4.9e-90 302.0 0.0 6.4e-90 301.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 C1q PF00386.21 KFP01512.1 - 5.4e-39 133.3 2.1 6.6e-39 133.0 2.1 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFP01512.1 - 1.6e-08 34.2 13.1 2.3e-08 33.7 13.1 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Apyrase PF06079.11 KFP01513.1 - 1e-84 284.3 1.0 1.2e-84 284.0 1.0 1.0 1 0 0 1 1 1 1 Apyrase TIMP PF00965.17 KFP01514.1 - 5.6e-69 231.6 6.0 6.3e-69 231.4 6.0 1.0 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.21 KFP01514.1 - 0.0033 17.2 0.1 0.0091 15.8 0.1 1.8 1 1 0 1 1 1 1 UNC-6/NTR/C345C module UCH PF00443.29 KFP01515.1 - 4.2e-46 157.5 0.1 5.1e-46 157.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP01515.1 - 2.7e-21 76.5 0.4 4.1e-21 75.9 0.4 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2197 PF09963.9 KFP01515.1 - 0.12 12.6 1.7 7 7.0 0.2 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) DZR PF12773.7 KFP01515.1 - 3.4 7.8 7.4 3.5 7.7 1.8 3.1 2 1 0 2 2 2 0 Double zinc ribbon Seryl_tRNA_N PF02403.22 KFP01516.1 - 0.012 15.8 0.2 0.018 15.2 0.2 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Sec7 PF01369.20 KFP01517.1 - 3.1e-75 251.9 0.1 4.2e-75 251.5 0.1 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 KFP01517.1 - 1.1e-29 103.1 0.1 1.9e-29 102.3 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFP01517.1 - 3.5e-06 27.4 0.0 8.1e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KFP01517.1 - 0.0041 17.2 0.2 0.024 14.7 0.2 2.2 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 KFP01517.1 - 0.016 15.4 0.0 0.085 13.1 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Pilosulin PF17499.2 KFP01517.1 - 0.019 15.1 0.0 0.053 13.7 0.0 1.7 1 0 0 1 1 1 0 Ant venom peptides GPS2_interact PF15784.5 KFP01517.1 - 0.02 15.3 2.0 0.047 14.1 2.0 1.6 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain BBS2_C PF14782.6 KFP01517.1 - 0.032 13.0 1.9 1.5 7.5 1.3 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal PH_16 PF17838.1 KFP01517.1 - 0.053 13.4 0.0 0.42 10.5 0.0 2.2 2 0 0 2 2 2 0 PH domain APG6_N PF17675.1 KFP01517.1 - 0.071 13.6 3.4 0.12 12.9 3.4 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region FlgN PF05130.12 KFP01517.1 - 0.075 13.5 1.6 0.15 12.6 1.6 1.4 1 0 0 1 1 1 0 FlgN protein NUDE_C PF04880.13 KFP01517.1 - 0.55 10.7 4.1 0.94 9.9 4.1 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region PLDc_2 PF13091.6 KFP01518.1 - 9.6e-14 51.4 0.0 7.6e-06 25.9 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KFP01518.1 - 0.005 17.0 2.1 0.19 12.0 0.2 2.9 2 1 0 2 2 2 2 Phospholipase D Active site motif SH2 PF00017.24 KFP01519.1 - 2e-10 40.6 0.0 4e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.16 KFP01519.1 - 1.4e-05 25.4 0.0 2.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 SOCS box Exostosin PF03016.15 KFP01519.1 - 0.0036 16.6 0.0 0.0045 16.2 0.0 1.1 1 0 0 1 1 1 1 Exostosin family Abhydrolase_3 PF07859.13 KFP01520.1 - 5.2e-17 62.4 2.9 1.4e-16 61.0 2.9 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KFP01520.1 - 1.8e-08 33.7 0.1 1.5e-05 24.1 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Hydrolase_4 PF12146.8 KFP01520.1 - 0.00081 18.7 0.1 0.0012 18.2 0.1 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KFP01520.1 - 0.002 18.0 0.0 0.0028 17.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KFP01520.1 - 0.0029 18.2 4.8 0.0049 17.5 4.6 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KFP01520.1 - 0.0035 16.8 0.0 0.0056 16.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family LIDHydrolase PF10230.9 KFP01520.1 - 0.0035 16.9 0.0 0.0043 16.6 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase FSH1 PF03959.13 KFP01520.1 - 0.0066 16.1 0.0 0.0094 15.6 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF2974 PF11187.8 KFP01520.1 - 0.039 13.5 0.0 0.058 12.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) DUF2235 PF09994.9 KFP01520.1 - 0.058 12.7 0.0 0.073 12.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) NYN PF01936.18 KFP01520.1 - 0.14 12.6 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 NYN domain Chlorophyllase2 PF12740.7 KFP01520.1 - 0.17 10.8 0.3 0.75 8.7 0.3 2.0 1 1 0 1 1 1 0 Chlorophyllase enzyme TK PF00265.18 KFP01521.1 - 1.8e-63 213.6 0.3 2.2e-63 213.3 0.3 1.1 1 0 0 1 1 1 1 Thymidine kinase mono-CXXC PF15626.6 KFP01521.1 - 0.88 10.0 3.5 1.4 9.3 0.1 2.6 3 0 0 3 3 3 0 single CXXC unit Arf PF00025.21 KFP01522.1 - 3.3e-18 65.7 0.0 3.8e-18 65.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP01522.1 - 0.01 15.4 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KFP01522.1 - 0.021 14.6 0.1 0.024 14.4 0.1 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KFP01522.1 - 0.1 12.5 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase Gtr1_RagA PF04670.12 KFP01522.1 - 0.2 11.0 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ribosomal_L12 PF00542.19 KFP01523.1 - 3.1e-19 69.1 6.3 3.1e-19 69.1 6.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KFP01523.1 - 4.4e-10 39.1 1.8 1.2e-09 37.7 0.5 2.3 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain DUF4479 PF14794.6 KFP01523.1 - 0.055 13.3 1.3 0.17 11.8 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) Mito_carr PF00153.27 KFP01524.1 - 1.1e-55 185.5 1.4 2.9e-17 62.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein FAM195 PF14799.6 KFP01525.1 - 4.7e-21 75.1 0.0 5.4e-21 74.9 0.0 1.0 1 0 0 1 1 1 1 FAM195 family Ank_5 PF13857.6 KFP01526.1 - 6.3e-13 48.7 1.1 8.2e-10 38.8 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP01526.1 - 1.1e-12 48.2 0.1 1.4e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP01526.1 - 4.9e-12 46.3 0.0 7.3e-07 29.7 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFP01526.1 - 1.1e-10 41.5 0.2 3e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFP01526.1 - 1.3e-09 37.5 0.2 0.00039 20.6 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Thioredoxin PF00085.20 KFP01527.1 - 3.4e-54 181.2 1.3 8.4e-26 90.0 0.1 3.8 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 KFP01527.1 - 4.9e-49 166.7 5.5 5.5e-44 150.3 3.4 2.8 2 1 1 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KFP01527.1 - 7.4e-12 45.2 0.3 4.7e-06 26.2 0.0 3.3 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KFP01527.1 - 7.4e-10 39.2 0.5 0.0039 17.6 0.1 3.6 3 1 0 3 3 3 2 Thioredoxin-like domain ERp29_N PF07912.13 KFP01527.1 - 3e-07 30.6 0.6 0.75 9.9 0.0 3.6 3 0 0 3 3 3 3 ERp29, N-terminal domain Thioredoxin_7 PF13899.6 KFP01527.1 - 3.1e-07 30.5 0.0 0.023 14.9 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KFP01527.1 - 7e-07 29.5 0.2 0.012 15.9 0.0 4.6 4 2 1 5 5 5 1 Thioredoxin-like AhpC-TSA PF00578.21 KFP01527.1 - 2.3e-05 24.3 0.8 0.81 9.6 0.0 3.7 3 1 0 4 4 4 2 AhpC/TSA family Redoxin PF08534.10 KFP01527.1 - 0.0032 17.2 1.8 0.52 10.0 0.0 3.3 2 1 1 3 3 3 1 Redoxin Glutaredoxin PF00462.24 KFP01527.1 - 0.0074 16.5 0.6 3.6 7.9 0.0 3.4 2 1 0 2 2 2 1 Glutaredoxin HyaE PF07449.11 KFP01527.1 - 0.027 14.4 0.0 0.18 11.8 0.0 2.2 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 KFP01527.1 - 0.065 13.0 0.0 7.2 6.4 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_3 PF13192.6 KFP01527.1 - 0.18 11.9 0.0 6.2 7.0 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin domain Rho_GDI PF02115.17 KFP01528.1 - 1.8e-82 275.8 0.4 2.1e-82 275.6 0.4 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor DUF4249 PF14054.6 KFP01528.1 - 0.041 13.5 0.1 0.045 13.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4249) FoP_duplication PF13865.6 KFP01529.1 - 1e-11 45.2 10.4 1.9e-11 44.3 10.4 1.6 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.22 KFP01529.1 - 3.4e-09 36.4 0.0 4.8e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTP_transf_like PF01467.26 KFP01530.1 - 1.2e-38 132.5 0.0 4.7e-23 82.0 0.0 2.1 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 KFP01530.1 - 0.0031 17.4 0.1 0.045 13.7 0.0 2.2 2 0 0 2 2 2 1 FAD synthetase CHAP PF05257.16 KFP01530.1 - 0.023 15.3 0.0 0.066 13.8 0.0 1.6 1 1 0 1 1 1 0 CHAP domain SIR2 PF02146.17 KFP01531.1 - 2.1e-28 99.4 1.6 1.2e-21 77.5 0.6 2.1 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 KFP01531.1 - 0.0013 18.5 0.0 0.49 10.1 0.0 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain bZIP_Maf PF03131.17 KFP01532.1 - 1.3e-33 115.4 11.7 1.6e-33 115.1 11.7 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 KFP01532.1 - 3.5e-05 23.8 15.7 0.00035 20.6 15.7 2.3 1 1 0 1 1 1 1 bZIP transcription factor DivIC PF04977.15 KFP01532.1 - 9.9e-05 22.0 5.8 9.9e-05 22.0 5.8 2.2 1 1 1 2 2 2 1 Septum formation initiator Prominin PF05478.11 KFP01532.1 - 0.00039 18.6 1.4 0.00047 18.3 1.4 1.0 1 0 0 1 1 1 1 Prominin DUF1192 PF06698.11 KFP01532.1 - 0.00056 19.9 5.7 0.024 14.7 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) DUF4164 PF13747.6 KFP01532.1 - 0.0021 18.3 2.9 0.0021 18.3 2.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4164) DUF2353 PF09789.9 KFP01532.1 - 0.003 17.0 5.9 0.0036 16.7 5.9 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Cnn_1N PF07989.11 KFP01532.1 - 0.0061 16.7 8.7 0.014 15.6 8.7 1.7 1 1 0 1 1 1 1 Centrosomin N-terminal motif 1 JIP_LZII PF16471.5 KFP01532.1 - 0.0071 16.5 2.6 0.0071 16.5 2.6 2.2 2 1 0 2 2 2 1 JNK-interacting protein leucine zipper II HAUS-augmin3 PF14932.6 KFP01532.1 - 0.014 15.0 6.2 0.017 14.7 6.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 ThrE_2 PF12821.7 KFP01532.1 - 0.015 15.4 0.1 0.022 14.9 0.1 1.1 1 0 0 1 1 1 0 Threonine/Serine exporter, ThrE FapA PF03961.13 KFP01532.1 - 0.017 13.8 4.9 0.022 13.4 4.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Tox-ODYAM1 PF15642.6 KFP01532.1 - 0.069 12.1 3.3 0.087 11.8 3.3 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus bZIP_2 PF07716.15 KFP01532.1 - 0.074 13.1 16.8 0.11 12.5 13.4 2.7 1 1 1 2 2 2 0 Basic region leucine zipper Mod_r PF07200.13 KFP01532.1 - 0.083 13.0 7.6 0.11 12.6 7.2 1.3 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein YabA PF06156.13 KFP01532.1 - 0.11 13.2 8.4 0.055 14.1 3.7 2.1 1 1 1 2 2 2 0 Initiation control protein YabA DUF3584 PF12128.8 KFP01532.1 - 0.22 9.0 8.4 0.25 8.8 8.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GIT_CC PF16559.5 KFP01532.1 - 0.28 11.1 6.0 0.24 11.3 4.1 1.9 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4407 PF14362.6 KFP01532.1 - 0.42 9.9 5.0 0.3 10.4 3.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DASH_Spc19 PF08287.11 KFP01532.1 - 0.43 10.4 10.9 0.64 9.9 10.9 1.3 1 0 0 1 1 1 0 Spc19 Spc7 PF08317.11 KFP01532.1 - 0.84 8.5 11.5 2.2 7.1 11.5 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein BST2 PF16716.5 KFP01532.1 - 0.86 10.2 9.6 1.7 9.3 9.2 1.7 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Mst1_SARAH PF11629.8 KFP01532.1 - 1 9.5 9.6 4.9 7.3 2.9 2.8 2 1 0 2 2 2 0 C terminal SARAH domain of Mst1 Nup54 PF13874.6 KFP01532.1 - 1.1 9.4 8.9 1.5 8.9 8.9 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 ZapB PF06005.12 KFP01532.1 - 1.3 9.5 16.4 1.3 9.5 8.8 2.6 1 1 1 2 2 2 0 Cell division protein ZapB Spc24 PF08286.11 KFP01532.1 - 1.9 8.7 9.1 0.63 10.3 5.4 1.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF2205 PF10224.9 KFP01532.1 - 2.1 8.4 9.8 0.73 9.9 4.9 2.1 1 1 1 2 2 2 0 Short coiled-coil protein APG6_N PF17675.1 KFP01532.1 - 2.3 8.8 15.2 8.6 6.9 15.2 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4140 PF13600.6 KFP01532.1 - 7.9 7.0 8.1 48 4.5 8.1 2.1 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) HALZ PF02183.18 KFP01532.1 - 8.8 6.6 13.4 11 6.3 4.2 2.9 2 1 1 3 3 3 0 Homeobox associated leucine zipper P5CR_dimer PF14748.6 KFP01533.1 - 1.9e-37 127.6 0.0 3.3e-37 126.9 0.0 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KFP01533.1 - 2.4e-08 34.4 0.0 4.6e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KFP01533.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MARVEL PF01284.23 KFP01534.1 - 3.2e-23 82.3 47.3 6.8e-13 48.9 17.2 2.1 2 0 0 2 2 2 2 Membrane-associating domain PAE PF03283.13 KFP01535.1 - 9.7e-75 251.9 0.0 1.2e-74 251.5 0.0 1.1 1 0 0 1 1 1 1 Pectinacetylesterase UBX PF00789.20 KFP01536.1 - 2.3e-11 43.7 0.0 2.1e-06 27.8 0.0 2.7 2 0 0 2 2 2 2 UBX domain TUG-UBL1 PF11470.8 KFP01536.1 - 5e-07 29.8 0.1 1.1e-06 28.7 0.1 1.7 1 0 0 1 1 1 1 TUG ubiquitin-like domain LRR_6 PF13516.6 KFP01537.1 - 1.6e-13 49.5 13.8 0.0016 18.4 0.2 5.6 5 0 0 5 5 5 4 Leucine Rich repeat LRR_1 PF00560.33 KFP01537.1 - 0.002 18.4 7.8 2.5 9.0 1.2 5.7 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.6 KFP01537.1 - 0.19 11.5 15.4 2.2 8.1 0.6 4.0 2 1 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 KFP01537.1 - 1.3 9.5 14.2 1.8 9.1 2.1 3.9 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Baculo_PEP_C PF04513.12 KFP01537.1 - 2.5 8.2 30.7 0.22 11.5 3.7 4.4 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ras PF00071.22 KFP01538.1 - 3.1e-50 169.9 0.0 3.6e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP01538.1 - 6.5e-19 68.3 0.0 8.5e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP01538.1 - 4e-05 23.1 0.0 4.9e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family CagD PF16567.5 KFP01538.1 - 0.072 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Pathogenicity island component CagD adh_short_C2 PF13561.6 KFP01539.1 - 6.3e-37 127.4 0.4 7e-37 127.2 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFP01539.1 - 1.1e-23 83.7 0.3 1.3e-23 83.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Fringe PF02434.16 KFP01540.1 - 1.3e-117 391.7 0.0 1.6e-117 391.5 0.0 1.0 1 0 0 1 1 1 1 Fringe-like Glyco_transf_21 PF13506.6 KFP01540.1 - 0.0073 15.8 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KFP01540.1 - 0.012 15.5 0.0 0.083 12.8 0.0 2.0 1 1 0 1 1 1 0 Glycosyltransferase like family 2 Galactosyl_T PF01762.21 KFP01540.1 - 0.022 14.5 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Galactosyltransferase RPN7 PF10602.9 KFP01541.1 - 9.6e-57 191.5 0.8 2e-56 190.5 0.8 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KFP01541.1 - 1.4e-17 64.1 1.2 6.9e-17 61.9 0.2 2.3 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 KFP01541.1 - 0.0048 16.9 4.5 0.16 12.1 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFP01541.1 - 0.039 13.6 1.0 0.12 12.1 0.0 2.3 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.28 KFP01541.1 - 0.093 12.6 5.2 0.19 11.6 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Dus PF01207.17 KFP01542.1 - 1.1e-56 192.3 0.1 1.5e-56 191.8 0.1 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF702 PF05142.12 KFP01542.1 - 7.1e-05 23.3 5.0 0.00014 22.3 5.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF702) Ribosomal_S14 PF00253.21 KFP01542.1 - 0.0035 17.1 1.0 0.0092 15.7 1.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e His_biosynth PF00977.21 KFP01542.1 - 0.0068 15.9 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein TMP-TENI PF02581.17 KFP01542.1 - 0.036 13.4 0.0 0.091 12.1 0.0 1.6 1 0 0 1 1 1 0 Thiamine monophosphate synthase DHO_dh PF01180.21 KFP01542.1 - 0.047 12.9 0.0 0.24 10.5 0.0 2.0 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase Acyl_transf_1 PF00698.21 KFP01543.1 - 1e-112 376.8 0.0 2.2e-112 375.7 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 KFP01543.1 - 1e-72 244.8 0.0 1.8e-72 244.0 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thioesterase PF00975.20 KFP01543.1 - 2.1e-61 208.0 0.1 2.1e-59 201.5 0.1 2.8 2 0 0 2 2 2 1 Thioesterase domain KR PF08659.10 KFP01543.1 - 4.8e-48 163.5 0.0 2.2e-47 161.3 0.0 2.2 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 KFP01543.1 - 1.3e-33 115.5 0.0 3.4e-33 114.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KFP01543.1 - 7.6e-33 113.3 0.0 1.8e-32 112.1 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 KFP01543.1 - 1.1e-19 70.9 0.0 1.8e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.26 KFP01543.1 - 1.4e-16 60.6 0.0 5.5e-16 58.7 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFP01543.1 - 2.3e-13 51.3 0.0 1.3e-12 49.0 0.0 2.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.25 KFP01543.1 - 1.1e-09 38.4 0.8 2.9e-09 37.1 0.8 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 KFP01543.1 - 4e-07 29.7 0.0 2.9e-05 23.6 0.0 2.8 2 0 0 2 2 2 1 short chain dehydrogenase Thiolase_N PF00108.23 KFP01543.1 - 6.9e-05 22.3 0.0 0.00024 20.6 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain YjeF_N PF03853.15 KFP01543.1 - 0.002 18.0 0.1 1.2 9.0 0.0 3.9 4 0 0 4 4 4 1 YjeF-related protein N-terminus ACP_syn_III PF08545.10 KFP01543.1 - 0.019 14.8 0.2 0.074 12.9 0.2 2.1 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_23 PF13489.6 KFP01543.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PI3K_P85_iSH2 PF16454.5 KFP01545.1 - 0.0029 17.2 1.4 0.0031 17.1 1.4 1.0 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain BLOC1S3 PF15753.5 KFP01545.1 - 0.0065 16.6 0.4 0.0065 16.6 0.4 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF4763 PF15960.5 KFP01545.1 - 0.012 14.9 0.8 0.012 14.9 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DivIC PF04977.15 KFP01545.1 - 0.017 14.8 0.7 0.018 14.8 0.7 1.2 1 0 0 1 1 1 0 Septum formation initiator MbeD_MobD PF04899.12 KFP01545.1 - 0.027 14.6 1.9 0.044 13.9 2.0 1.3 1 1 0 1 1 1 0 MbeD/MobD like MFS_1 PF07690.16 KFP01546.1 - 2.1e-35 122.3 44.3 1.4e-33 116.3 28.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 KFP01547.1 - 2.9e-20 72.7 0.0 3.7e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP01547.1 - 7.6e-13 48.3 0.0 1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP01547.1 - 6.7e-10 38.3 0.1 9.6e-10 37.8 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP01547.1 - 0.00036 20.6 0.0 0.0014 18.6 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KFP01547.1 - 0.049 12.6 0.1 0.07 12.1 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KFP01547.1 - 0.094 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M10 PF00413.24 KFP01548.1 - 6.3e-61 204.8 0.0 8.6e-61 204.4 0.0 1.2 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.18 KFP01548.1 - 4e-10 39.7 0.1 2.3e-09 37.3 0.0 2.1 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Astacin PF01400.24 KFP01548.1 - 2.6e-05 23.9 0.9 0.16 11.6 0.0 2.3 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Peptidase_M66 PF10462.9 KFP01548.1 - 0.019 13.9 0.1 0.031 13.2 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M54 PF07998.11 KFP01548.1 - 0.027 14.4 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 Metallopep PF12044.8 KFP01548.1 - 0.034 12.7 0.0 0.053 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_3 PF13582.6 KFP01548.1 - 0.089 13.3 0.8 0.16 12.5 0.8 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFP01548.1 - 0.19 11.9 0.2 0.34 11.0 0.2 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KFP01548.1 - 0.21 11.2 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 KFP01548.1 - 0.22 10.7 0.7 0.4 9.8 0.7 1.3 1 0 0 1 1 1 0 Met-zincin Pkinase_Tyr PF07714.17 KFP01549.1 - 4.4e-37 127.8 0.0 6.2e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP01549.1 - 3.2e-33 115.2 0.0 5.1e-33 114.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain CARD PF00619.21 KFP01549.1 - 7.1e-19 67.6 0.4 1.7e-18 66.4 0.4 1.6 1 0 0 1 1 1 1 Caspase recruitment domain Kinase-like PF14531.6 KFP01549.1 - 0.0062 15.9 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFP01549.1 - 0.24 11.3 0.2 0.48 10.3 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family AA_permease_2 PF13520.6 KFP01550.1 - 1.8e-63 214.8 34.4 2.2e-63 214.6 34.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFP01550.1 - 6.3e-25 87.7 33.0 9.3e-25 87.1 33.0 1.2 1 0 0 1 1 1 1 Amino acid permease Pyr_redox_3 PF13738.6 KFP01552.1 - 3.2e-09 36.5 0.0 5.6e-06 25.8 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFP01552.1 - 0.0019 17.5 0.0 0.06 12.6 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Nbs1_C PF08599.10 KFP01553.1 - 1.6e-33 114.6 1.1 4.9e-33 113.1 0.1 2.4 2 0 0 2 2 2 1 DNA damage repair protein Nbs1 NIBRIN_BRCT_II PF16508.5 KFP01553.1 - 2e-28 99.1 4.6 2.9e-28 98.6 0.0 3.4 5 0 0 5 5 5 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 KFP01553.1 - 7.2e-14 51.9 0.2 1.9e-13 50.5 0.2 1.8 1 0 0 1 1 1 1 FHA domain BRCT PF00533.26 KFP01553.1 - 7.5e-10 39.1 0.1 1.8e-07 31.4 0.1 2.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Yop-YscD_cpl PF16697.5 KFP01553.1 - 1.5e-06 28.4 0.0 4.5e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain RTT107_BRCT_5 PF16770.5 KFP01553.1 - 1.3e-05 25.0 0.1 3.8e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 KFP01553.1 - 0.00012 21.9 0.1 0.00025 20.9 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain DUF4554 PF15091.6 KFP01553.1 - 0.17 10.8 2.9 0.34 9.7 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) EF-hand_1 PF00036.32 KFP01554.1 - 2.1e-24 83.2 10.3 1.4e-07 30.6 1.0 5.4 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KFP01554.1 - 3e-23 79.7 9.9 8.9e-08 31.5 0.6 5.5 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 KFP01554.1 - 2e-21 76.2 7.4 3e-11 43.6 2.2 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KFP01554.1 - 3.2e-15 54.8 8.1 0.00035 19.9 0.0 4.7 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 KFP01554.1 - 1.3e-09 37.7 2.7 2.3e-06 27.3 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain pair T3SS_HrpK1 PF16937.5 KFP01554.1 - 0.0007 19.3 0.2 0.1 12.2 0.0 2.4 2 1 1 3 3 3 1 Type III secretion system translocator protein, HrpF SPARC_Ca_bdg PF10591.9 KFP01554.1 - 0.0027 18.0 3.8 1.1 9.6 0.1 3.4 1 1 2 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region LXG PF04740.12 KFP01554.1 - 0.014 15.1 3.9 1.2 8.8 0.2 3.0 3 0 0 3 3 3 0 LXG domain of WXG superfamily Caleosin PF05042.13 KFP01554.1 - 0.024 14.6 2.2 2.8 7.8 0.1 3.2 1 1 3 4 4 4 0 Caleosin related protein Styelin PF17562.2 KFP01554.1 - 0.035 14.5 0.1 0.57 10.6 0.0 2.5 2 0 0 2 2 2 0 Styelin ArgoMid PF16487.5 KFP01554.1 - 0.092 13.0 0.5 3.6 7.9 0.0 3.0 3 1 0 3 3 3 0 Mid domain of argonaute EF-hand_9 PF14658.6 KFP01554.1 - 0.13 12.6 0.1 27 5.2 0.0 3.1 2 1 0 2 2 2 0 EF-hand domain EF-hand_10 PF14788.6 KFP01554.1 - 0.16 11.9 10.3 2.6 8.0 0.4 4.3 3 1 1 4 4 4 0 EF hand Dockerin_1 PF00404.18 KFP01554.1 - 0.24 11.6 3.0 1.8 8.8 0.1 3.1 2 2 2 4 4 4 0 Dockerin type I domain ABM PF03992.16 KFP01555.1 - 3.5e-09 36.7 0.1 6.5e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase EF-hand_1 PF00036.32 KFP01555.1 - 6.3e-06 25.4 0.8 0.044 13.3 0.1 2.9 1 1 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFP01555.1 - 1e-05 25.1 0.4 0.0051 16.6 0.1 2.9 1 1 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KFP01555.1 - 2.6e-05 24.6 2.7 0.0015 18.9 0.3 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KFP01555.1 - 0.0033 17.2 1.8 0.083 12.8 1.8 2.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KFP01555.1 - 0.0091 15.5 0.9 0.72 9.5 0.0 3.2 2 1 1 3 3 3 1 EF hand UCH_1 PF13423.6 KFP01555.1 - 0.032 13.8 5.9 0.037 13.6 5.5 1.3 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase EF-hand_10 PF14788.6 KFP01555.1 - 0.057 13.3 1.9 2.4 8.1 0.7 3.7 3 1 0 3 3 3 0 EF hand SICA_beta PF12878.7 KFP01555.1 - 0.08 13.1 0.2 0.2 11.8 0.2 1.7 1 0 0 1 1 1 0 SICA extracellular beta domain Exonuc_VII_S PF02609.16 KFP01555.1 - 0.12 12.4 8.5 1.1 9.3 0.2 3.5 3 0 0 3 3 3 0 Exonuclease VII small subunit MRP-L28 PF09812.9 KFP01555.1 - 0.59 10.3 5.4 0.26 11.4 0.4 2.3 2 1 1 3 3 3 0 Mitochondrial ribosomal protein L28 AAA_23 PF13476.6 KFP01555.1 - 0.83 10.1 11.4 0.98 9.9 3.9 2.2 1 1 1 2 2 2 0 AAA domain Uso1_p115_C PF04871.13 KFP01555.1 - 1.6 9.1 6.7 3 8.2 1.5 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region ZapB PF06005.12 KFP01555.1 - 2.1 8.9 9.3 1.3 9.5 0.1 2.9 2 2 0 2 2 2 0 Cell division protein ZapB eIF_4EBP PF05456.11 KFP01556.1 - 0.014 15.3 0.0 0.014 15.3 0.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Tmemb_55A PF09788.9 KFP01557.1 - 1e-96 322.8 15.7 1.1e-96 322.7 15.7 1.0 1 0 0 1 1 1 1 Transmembrane protein 55A zf-BED PF02892.15 KFP01557.1 - 0.015 15.3 9.3 0.4 10.7 0.0 3.8 3 1 1 4 4 4 0 BED zinc finger zinc_ribbon_12 PF11331.8 KFP01557.1 - 0.084 12.7 0.6 0.084 12.7 0.6 3.8 3 1 1 4 4 4 0 Probable zinc-ribbon domain zinc_ribbon_4 PF13717.6 KFP01557.1 - 0.48 10.4 0.0 0.48 10.4 0.0 4.9 5 1 1 6 6 6 0 zinc-ribbon domain OTU PF02338.19 KFP01558.1 - 1.7e-32 112.6 1.9 2.1e-32 112.3 0.0 2.0 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KFP01558.1 - 4e-09 36.3 0.1 6.3e-05 22.5 0.0 2.8 1 1 2 3 3 3 2 Peptidase C65 Otubain IFP_35_N PF07334.13 KFP01558.1 - 0.013 15.6 3.8 0.034 14.2 3.8 1.7 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus PIN_8 PF18476.1 KFP01558.1 - 1.8 8.4 8.3 1 9.2 6.0 1.6 1 1 1 2 2 2 0 PIN like domain Sulfate_transp PF00916.20 KFP01559.1 - 2.4e-92 309.6 21.5 2.7e-92 309.5 21.5 1.0 1 0 0 1 1 1 1 Sulfate permease family MFS_MOT1 PF16983.5 KFP01559.1 - 0.0083 16.5 4.8 0.0083 16.5 4.8 3.3 3 1 0 3 3 3 1 Molybdate transporter of MFS superfamily COesterase PF00135.28 KFP01561.1 - 4e-198 659.5 0.0 4.9e-198 659.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFP01561.1 - 4.7e-07 29.9 0.1 3.1e-06 27.2 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold SCF PF02404.15 KFP01561.1 - 0.13 11.6 0.0 2.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Stem cell factor HAD_2 PF13419.6 KFP01562.1 - 4.4e-13 49.7 0.0 5.5e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFP01562.1 - 3.4e-10 40.6 0.0 4.5e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NaeI PF09126.10 KFP01562.1 - 0.044 13.0 0.0 0.058 12.6 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease NaeI Hydrolase_6 PF13344.6 KFP01562.1 - 0.14 12.3 0.0 0.41 10.8 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Sulfatase PF00884.23 KFP01563.1 - 1.1e-93 314.0 0.0 1.4e-93 313.7 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KFP01563.1 - 2.9e-42 144.3 0.9 5.4e-42 143.4 0.9 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 KFP01563.1 - 1.7e-08 34.5 0.1 0.00011 22.0 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Patatin PF01734.22 KFP01564.1 - 8.1e-16 58.8 0.5 2.4e-14 54.0 0.5 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase fn3 PF00041.21 KFP01565.1 - 1.4e-40 137.5 9.9 6.1e-15 55.3 0.1 4.3 4 0 0 4 4 4 4 Fibronectin type III domain Cys_box PF17869.1 KFP01565.1 - 1.2e-25 89.4 12.3 1.2e-25 89.4 12.3 2.5 2 0 0 2 2 2 1 Anosmin cysteine rich domain WAP PF00095.21 KFP01565.1 - 5e-10 39.6 15.7 5e-10 39.6 15.7 2.6 2 1 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Interfer-bind PF09294.10 KFP01565.1 - 2.2e-05 24.7 0.6 0.0029 17.9 0.0 3.2 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III DUF4959 PF16323.5 KFP01565.1 - 0.041 14.2 0.0 0.14 12.5 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4959) DUF2369 PF10179.9 KFP01565.1 - 0.043 14.2 1.5 1.9 9.0 1.3 3.1 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) WD40 PF00400.32 KFP01567.1 - 5.4e-47 156.8 25.0 1.7e-10 41.3 0.2 8.5 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP01567.1 - 1.1e-28 99.3 0.8 7.2e-09 35.8 0.0 5.5 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP01567.1 - 4.2e-11 43.1 0.5 0.0018 18.2 0.1 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFP01567.1 - 1.3e-05 24.3 0.9 0.13 11.1 0.0 3.4 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFP01567.1 - 0.00034 20.0 0.0 1.1 8.5 0.0 2.8 3 1 0 3 3 3 2 WD40-like domain PD40 PF07676.12 KFP01567.1 - 0.036 14.0 0.0 0.28 11.2 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat K_channel_TID PF07941.11 KFP01567.1 - 0.042 14.3 5.7 0.081 13.4 5.7 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Nup160 PF11715.8 KFP01567.1 - 0.051 12.2 4.8 0.27 9.8 0.0 3.3 2 2 3 5 5 5 0 Nucleoporin Nup120/160 Glyco_hydro_11 PF00457.17 KFP01567.1 - 0.09 12.4 1.2 2.8 7.6 0.1 2.6 2 0 0 2 2 2 0 Glycosyl hydrolases family 11 IKI3 PF04762.12 KFP01567.1 - 0.094 10.7 0.3 2.4 6.0 0.0 2.4 2 1 0 2 2 2 0 IKI3 family Ocular_alb PF02101.15 KFP01569.1 - 7.4e-202 670.6 8.3 8.8e-202 670.3 8.3 1.0 1 0 0 1 1 1 1 Ocular albinism type 1 protein 7tm_2 PF00002.24 KFP01569.1 - 0.00017 21.0 11.6 0.00032 20.0 11.4 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF412 PF04217.13 KFP01569.1 - 0.11 12.3 0.3 0.32 10.9 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF412 ASD2 PF08687.11 KFP01570.1 - 3.5e-120 401.0 26.1 3.5e-120 401.0 26.1 3.8 3 1 0 3 3 3 1 Apx/Shroom domain ASD2 ASD1 PF08688.10 KFP01570.1 - 3.3e-59 200.3 6.0 3.3e-59 200.3 6.0 5.4 6 2 1 7 7 7 1 Apx/Shroom domain ASD1 Claudin_2 PF13903.6 KFP01571.1 - 7.4e-14 51.9 7.0 1.2e-13 51.3 7.0 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFP01571.1 - 4.4e-06 26.7 8.5 7.8e-06 25.9 8.5 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family YtpI PF14007.6 KFP01571.1 - 0.5 10.5 5.9 0.077 13.1 1.3 1.9 2 0 0 2 2 2 0 YtpI-like protein UnbV_ASPIC PF07593.12 KFP01572.1 - 0.21 11.6 0.3 32 4.6 0.2 2.9 2 0 0 2 2 2 0 ASPIC and UnbV DUF4055 PF13264.6 KFP01572.1 - 6 7.0 7.4 8.5 6.5 0.4 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4055) Voltage_CLC PF00654.20 KFP01573.1 - 1.5e-106 356.7 18.0 1.5e-106 356.7 18.0 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KFP01573.1 - 2.6e-13 50.2 0.7 6.5e-07 29.7 0.1 2.5 2 0 0 2 2 2 2 CBS domain COS PF18568.1 KFP01574.1 - 5.6e-33 112.7 1.0 1.3e-32 111.5 0.2 2.1 3 0 0 3 3 3 1 TRIM C-terminal subgroup One Signature domain SPRY PF00622.28 KFP01574.1 - 1.1e-16 61.0 0.0 2.5e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 SPRY domain PRY PF13765.6 KFP01574.1 - 8.9e-13 47.7 0.0 2.8e-12 46.0 0.0 1.9 1 0 0 1 1 1 1 SPRY-associated domain zf-B_box PF00643.24 KFP01574.1 - 3.5e-09 36.7 0.8 3.5e-09 36.7 0.8 4.9 4 1 0 4 4 3 2 B-box zinc finger fn3 PF00041.21 KFP01574.1 - 3.2e-08 33.8 0.2 6.6e-08 32.8 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III domain zf-RING_UBOX PF13445.6 KFP01574.1 - 4.1e-07 29.9 9.6 4.1e-07 29.9 9.6 3.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFP01574.1 - 1.2e-06 28.3 7.5 1.2e-06 28.3 7.5 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP01574.1 - 3.6e-06 26.7 11.6 3.6e-06 26.7 11.6 3.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFP01574.1 - 9.4e-06 25.7 12.3 9.4e-06 25.7 12.3 4.7 4 1 1 5 5 5 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KFP01574.1 - 1.1e-05 25.2 7.1 1.1e-05 25.2 7.1 3.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP01574.1 - 7.7e-05 23.0 11.4 7.7e-05 23.0 11.4 3.3 3 0 0 3 3 2 2 Ring finger domain zf-RING_5 PF14634.6 KFP01574.1 - 0.0017 18.3 9.9 0.0017 18.3 9.9 3.7 3 1 0 3 3 2 1 zinc-RING finger domain Pur_ac_phosph_N PF16656.5 KFP01574.1 - 0.0066 17.0 0.3 0.018 15.6 0.2 1.9 2 0 0 2 2 1 1 Purple acid Phosphatase, N-terminal domain fn3_4 PF16794.5 KFP01574.1 - 0.084 12.8 0.0 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 Fibronectin-III type domain U-box PF04564.15 KFP01574.1 - 0.2 11.8 1.2 0.94 9.7 0.2 2.6 2 1 0 2 2 2 0 U-box domain RhoGAP PF00620.27 KFP01575.1 - 7.5e-48 162.2 0.1 1.9e-47 160.9 0.1 1.7 1 0 0 1 1 1 1 RhoGAP domain DUF1679 PF07914.11 KFP01575.1 - 0.061 12.2 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) FERM_M PF00373.18 KFP01577.1 - 2.9e-18 66.4 0.1 9e-18 64.8 0.1 1.9 1 0 0 1 1 1 1 FERM central domain WW PF00397.26 KFP01577.1 - 0.0013 18.7 0.1 0.003 17.6 0.1 1.7 1 0 0 1 1 1 1 WW domain FERM_f0 PF16511.5 KFP01577.1 - 0.0034 17.6 0.0 0.0081 16.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM Vfa1 PF08432.10 KFP01577.1 - 1.6 9.0 11.8 0.05 13.9 2.1 2.9 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 Pribosyl_synth PF14572.6 KFP01578.1 - 4.7e-45 153.9 1.9 2e-37 129.0 0.6 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KFP01578.1 - 2.6e-33 114.4 0.2 1.2e-32 112.2 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KFP01578.1 - 1e-13 51.1 0.2 2e-13 50.2 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KFP01578.1 - 0.00032 20.2 0.1 0.00052 19.5 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Chlorosome_CsmC PF11098.8 KFP01578.1 - 0.12 12.4 0.4 0.2 11.7 0.4 1.4 1 0 0 1 1 1 0 Chlorosome envelope protein C DUF3247 PF11607.8 KFP01578.1 - 0.16 12.3 0.1 0.35 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) LRR_8 PF13855.6 KFP01579.1 - 6e-76 250.1 89.1 3.4e-11 42.7 3.5 14.5 11 3 3 14 14 14 14 Leucine rich repeat LRR_4 PF12799.7 KFP01579.1 - 1e-35 121.1 96.8 6.3e-06 26.4 2.8 14.6 8 4 10 18 18 18 14 Leucine Rich repeats (2 copies) TIR PF01582.20 KFP01579.1 - 1.7e-16 60.5 0.2 2.7e-16 59.8 0.2 1.3 1 0 0 1 1 1 1 TIR domain LRR_5 PF13306.6 KFP01579.1 - 8.1e-14 51.7 34.1 7.9e-06 25.8 0.2 7.4 5 1 0 7 7 7 5 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP01579.1 - 1.4e-13 50.7 34.1 0.00033 20.2 5.5 7.2 4 2 3 7 7 7 6 Leucine-rich repeat LRR_12 PF18837.1 KFP01579.1 - 7.2e-12 44.7 0.2 7.2e-12 44.7 0.2 4.2 3 0 0 3 3 3 1 Leucine-rich repeat LRR_1 PF00560.33 KFP01579.1 - 3e-10 39.2 84.3 1.4 9.8 0.1 20.8 21 3 1 22 22 22 7 Leucine Rich Repeat TIR_2 PF13676.6 KFP01579.1 - 5.7e-09 36.6 0.2 2e-08 34.9 0.1 1.9 2 0 0 2 2 2 1 TIR domain LRR_6 PF13516.6 KFP01579.1 - 0.00011 21.9 66.1 4.2 7.7 0.1 17.2 19 0 0 19 19 19 3 Leucine Rich repeat Yae1_N PF09811.9 KFP01580.1 - 1.4e-11 43.9 35.4 5.1e+02 0.5 35.4 3.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal EGF_CA PF07645.15 KFP01581.1 - 1.9e-23 82.4 39.6 5e-11 42.6 9.9 6.1 4 2 2 6 6 6 3 Calcium-binding EGF domain MAM PF00629.23 KFP01581.1 - 1.4e-20 73.8 0.0 3.6e-20 72.5 0.0 1.7 1 1 0 1 1 1 1 MAM domain, meprin/A5/mu cEGF PF12662.7 KFP01581.1 - 5.4e-15 55.0 40.8 5.1e-05 23.1 0.3 5.7 5 0 0 5 5 5 5 Complement Clr-like EGF-like EGF PF00008.27 KFP01581.1 - 5.6e-12 45.7 69.4 3.3e-05 24.1 5.3 5.8 5 0 0 5 5 5 4 EGF-like domain EGF_3 PF12947.7 KFP01581.1 - 2e-11 43.9 21.9 9e-10 38.6 11.3 6.3 4 1 1 5 5 5 3 EGF domain FXa_inhibition PF14670.6 KFP01581.1 - 3.3e-09 36.9 75.4 4.8e-06 26.7 8.2 5.7 3 1 2 5 5 5 4 Coagulation Factor Xa inhibitory site hEGF PF12661.7 KFP01581.1 - 0.0021 18.6 1.2 0.0021 18.6 1.2 6.9 6 0 0 6 6 6 3 Human growth factor-like EGF MYT1 PF08474.11 KFP01581.1 - 0.16 11.9 0.9 0.26 11.2 0.9 1.3 1 0 0 1 1 1 0 Myelin transcription factor 1 TFIIS_M PF07500.14 KFP01582.1 - 8.3e-28 97.1 1.4 8.3e-28 97.1 1.4 2.0 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain Med26 PF08711.11 KFP01582.1 - 6.4e-09 35.7 0.1 2e-08 34.1 0.1 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TFIIS_C PF01096.18 KFP01582.1 - 0.017 15.0 4.9 0.027 14.3 0.2 2.8 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) MutS_III PF05192.18 KFP01582.1 - 0.031 14.5 1.1 0.05 13.8 0.8 1.5 1 1 0 1 1 1 0 MutS domain III Ribosomal_L37e PF01907.19 KFP01582.1 - 0.11 12.7 3.2 1.3 9.2 0.2 2.5 2 0 0 2 2 2 0 Ribosomal protein L37e Ras PF00071.22 KFP01583.1 - 1.5e-57 193.7 0.0 1.7e-57 193.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP01583.1 - 3.6e-30 104.6 0.0 5.7e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP01583.1 - 7e-12 45.1 0.0 8.1e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP01583.1 - 5.3e-06 26.5 0.0 8.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP01583.1 - 4.3e-05 23.5 0.0 0.011 15.6 0.1 2.3 2 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KFP01583.1 - 0.00014 21.3 0.0 0.00018 21.0 0.0 1.2 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 KFP01583.1 - 0.0051 16.6 0.2 0.028 14.2 0.0 1.9 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 KFP01583.1 - 0.007 16.1 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 KFP01583.1 - 0.0086 15.3 2.4 0.17 11.0 0.2 2.5 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.27 KFP01583.1 - 0.018 14.6 0.0 0.058 12.9 0.0 1.8 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 KFP01583.1 - 0.02 14.4 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KFP01583.1 - 0.022 15.1 0.0 0.031 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 KFP01583.1 - 0.14 11.7 0.1 0.21 11.1 0.0 1.7 1 1 1 2 2 2 0 Ferrous iron transport protein B AAA_22 PF13401.6 KFP01583.1 - 0.14 12.4 0.0 1.5 9.1 0.0 2.2 2 1 1 3 3 3 0 AAA domain Sedlin_N PF04628.13 KFP01584.1 - 1.9e-48 163.9 0.4 2.2e-48 163.7 0.4 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KFP01584.1 - 2.2e-09 37.4 0.1 2.8e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 Sybindin-like family Suv3_N PF18114.1 KFP01584.1 - 0.026 14.6 0.1 0.032 14.3 0.1 1.1 1 0 0 1 1 1 0 Suv3 helical N-terminal domain LisH_2 PF16045.5 KFP01585.1 - 1.7e-14 52.5 0.5 4.1e-14 51.3 0.5 1.7 1 0 0 1 1 1 1 LisH LisH PF08513.11 KFP01585.1 - 0.0071 16.3 0.1 0.026 14.5 0.0 2.1 2 0 0 2 2 2 1 LisH FOP_dimer PF09398.10 KFP01585.1 - 0.01 16.1 2.1 0.8 10.0 0.0 4.1 4 0 0 4 4 4 0 FOP N terminal dimerisation domain DUF3301 PF11743.8 KFP01585.1 - 1.1 9.0 3.5 2.8 7.7 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) Myelin_PLP PF01275.19 KFP01586.1 - 1e-99 333.2 18.6 1.2e-99 333.0 18.6 1.0 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) PspB PF06667.12 KFP01586.1 - 0.074 13.1 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Phage shock protein B LapA_dom PF06305.11 KFP01586.1 - 0.15 11.9 1.6 0.36 10.7 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Saf_2TM PF18303.1 KFP01586.1 - 0.28 10.7 3.2 0.67 9.5 0.6 2.5 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain GEMIN8 PF15348.6 KFP01587.1 - 7.2e-95 317.7 19.9 8.1e-95 317.5 19.9 1.0 1 0 0 1 1 1 1 Gemini of Cajal bodies-associated protein 8 Neur_chan_LBD PF02931.23 KFP01588.1 - 1.9e-52 177.8 0.0 2.5e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP01588.1 - 2e-40 139.4 0.1 7.7e-34 117.8 0.0 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region CRAL_TRIO PF00650.20 KFP01590.1 - 4.6e-28 97.9 0.5 7.5e-28 97.2 0.5 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Motile_Sperm PF00635.26 KFP01590.1 - 9.6e-22 76.9 0.0 2.3e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 MSP (Major sperm protein) domain CRAL_TRIO_2 PF13716.6 KFP01590.1 - 0.031 14.4 0.1 0.058 13.5 0.1 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Zn-C2H2_12 PF18112.1 KFP01591.1 - 0.18 12.3 0.0 0.89 10.1 0.0 1.9 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Ank_4 PF13637.6 KFP01592.1 - 2.4e-31 107.7 2.3 6.6e-08 32.9 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP01592.1 - 6e-30 103.7 2.9 9.7e-14 51.7 0.4 3.8 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP01592.1 - 1.6e-24 83.3 3.4 0.018 15.5 0.2 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 KFP01592.1 - 1.6e-24 85.2 9.4 0.0012 19.3 0.1 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 KFP01592.1 - 3.7e-18 65.3 3.4 1.2e-05 25.5 0.2 5.2 2 2 3 5 5 5 4 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFP01592.1 - 1.9e-06 28.1 3.3 3.5e-06 27.3 3.3 1.5 1 0 0 1 1 1 1 SOCS box Phospholip_A2_2 PF05826.12 KFP01592.1 - 0.042 14.1 1.0 6.5 7.1 0.1 2.3 2 0 0 2 2 2 0 Phospholipase A2 DUF1843 PF08898.10 KFP01592.1 - 0.091 13.3 0.0 6.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Ank_2 PF12796.7 KFP01593.1 - 4.7e-40 136.1 8.2 3.8e-13 49.8 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP01593.1 - 8.6e-30 102.7 2.5 6.4e-10 39.4 0.1 4.8 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP01593.1 - 2.3e-28 95.1 2.9 0.0016 18.7 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KFP01593.1 - 1.4e-26 92.2 6.3 7.2e-07 29.4 0.1 5.4 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KFP01593.1 - 2.7e-26 90.8 6.6 0.00096 19.5 0.1 6.9 6 1 1 7 7 7 6 Ankyrin repeat SOCS_box PF07525.16 KFP01593.1 - 1.1e-11 44.9 3.2 2.3e-11 43.9 3.2 1.5 1 0 0 1 1 1 1 SOCS box Nucleotid_trans PF03407.16 KFP01593.1 - 0.21 11.6 0.0 0.58 10.1 0.0 1.7 2 0 0 2 2 2 0 Nucleotide-diphospho-sugar transferase CXCXC PF03128.14 KFP01594.1 - 0.022 15.2 5.2 0.022 15.2 5.2 6.0 6 0 0 6 6 6 0 CXCXC repeat Collectrin PF16959.5 KFP01595.1 - 9.4e-69 230.1 0.3 1.5e-68 229.4 0.3 1.3 1 0 0 1 1 1 1 Renal amino acid transporter YajC PF02699.15 KFP01595.1 - 0.011 15.6 0.9 0.02 14.8 0.0 1.9 3 0 0 3 3 3 0 Preprotein translocase subunit DUF5305 PF17231.2 KFP01595.1 - 0.023 14.1 0.0 0.045 13.2 0.0 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5305) MscL PF01741.18 KFP01595.1 - 0.031 14.6 0.1 0.06 13.7 0.1 1.4 1 1 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL UPF0524 PF15823.5 KFP01595.1 - 0.054 12.9 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 UPF0524 of C3orf70 DUF4381 PF14316.6 KFP01595.1 - 0.062 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CcmH PF03918.14 KFP01595.1 - 0.068 12.5 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Cytochrome C biogenesis protein EphA2_TM PF14575.6 KFP01595.1 - 0.092 13.6 0.1 0.26 12.2 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Pilin_N PF07790.11 KFP01595.1 - 0.11 13.4 0.3 0.78 10.7 0.0 2.3 3 1 0 3 3 3 0 Archaeal Type IV pilin, N-terminal zf-CCCH PF00642.24 KFP01596.1 - 9.5e-13 47.7 13.0 1.6e-06 27.9 4.2 2.8 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFP01596.1 - 2.9e-06 27.1 13.6 0.00019 21.3 2.3 2.7 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KFP01596.1 - 6.9e-06 25.7 12.4 0.00047 19.9 4.3 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger RRM_1 PF00076.22 KFP01596.1 - 9.5e-05 22.1 0.0 0.00021 21.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFP01596.1 - 0.0056 16.7 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Torus PF16131.5 KFP01596.1 - 0.013 16.2 0.2 0.013 16.2 0.2 4.1 3 2 0 3 3 3 0 Torus domain DUF3430 PF11912.8 KFP01596.1 - 0.11 12.5 0.6 0.17 11.9 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) Clat_adaptor_s PF01217.20 KFP01598.1 - 2.2e-60 202.7 2.2 2.6e-60 202.5 2.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF629 PF04780.12 KFP01598.1 - 0.002 16.7 0.3 0.0026 16.4 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF629) PulA_N1 PF17999.1 KFP01598.1 - 0.07 13.9 0.1 0.13 13.1 0.1 1.4 1 0 0 1 1 1 0 Pullulanase N1-terminal domain 7tm_1 PF00001.21 KFP01599.1 - 6.2e-55 186.4 13.7 8.2e-55 186.0 13.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFP01599.1 - 1.7e-09 37.4 10.3 3e-09 36.7 10.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.9 KFP01599.1 - 2.1e-09 37.1 13.4 2.1e-09 37.1 13.4 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP01599.1 - 0.00011 22.1 12.2 0.00026 20.8 12.2 1.7 1 1 0 1 1 1 1 Olfactory receptor CTP_synth_N PF06418.14 KFP01600.1 - 1.9e-123 411.0 0.1 2.4e-123 410.7 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KFP01600.1 - 1.3e-56 191.4 0.0 2.2e-56 190.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KFP01600.1 - 2.4e-09 37.3 0.0 6.5e-09 35.9 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 KFP01600.1 - 0.0051 16.9 0.0 0.013 15.5 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain VWD PF00094.25 KFP01601.1 - 2.8e-26 92.7 0.0 9.5e-12 45.5 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type D domain C8 PF08742.11 KFP01601.1 - 2.4e-21 75.9 1.3 2.4e-21 75.9 1.3 3.1 3 0 0 3 3 3 1 C8 domain TIL PF01826.17 KFP01601.1 - 5.2e-21 74.6 34.1 4.2e-12 46.1 12.6 4.9 5 0 0 5 5 5 2 Trypsin Inhibitor like cysteine rich domain TILa PF12714.7 KFP01601.1 - 2e-08 34.1 8.2 2e-08 34.1 8.2 4.4 3 2 2 5 5 5 1 TILa domain TILa PF12714.7 KFP01602.1 - 1e-14 54.2 98.8 0.021 14.7 3.2 11.1 7 4 4 11 11 11 11 TILa domain RRM_7 PF16367.5 KFP01602.1 - 0.075 13.2 0.0 21 5.3 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif Dicty_spore_N PF04562.12 KFP01602.1 - 0.37 11.5 66.2 0.39 11.4 3.4 6.8 2 2 5 7 7 7 0 Dictyostelium spore coat protein, N terminus MACPF PF01823.19 KFP01603.1 - 1.7e-07 31.5 0.2 6.3e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 MAC/Perforin domain BTB PF00651.31 KFP01604.1 - 6.4e-27 94.0 0.3 1.1e-26 93.2 0.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFP01604.1 - 3.7e-16 58.7 17.6 4.2e-07 30.1 4.1 4.4 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFP01604.1 - 3.4e-12 46.1 20.7 2.1e-05 24.7 1.9 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP01604.1 - 2.7e-09 37.1 18.3 0.0042 17.8 1.1 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger DUF3342 PF11822.8 KFP01604.1 - 1.8e-05 24.8 0.1 3.5e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) zf-C2H2_2 PF12756.7 KFP01604.1 - 0.00075 19.8 7.0 0.076 13.4 0.0 3.4 1 1 2 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFP01604.1 - 0.0018 18.6 16.6 0.035 14.5 0.7 4.4 5 0 0 5 5 3 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFP01604.1 - 0.0028 17.4 3.7 1.2 8.9 0.2 2.9 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFP01604.1 - 0.011 15.9 9.9 0.11 12.9 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KFP01604.1 - 0.073 13.5 8.7 2.7 8.5 1.2 3.5 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger BTB_2 PF02214.22 KFP01604.1 - 0.1 13.0 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain PyrI_C PF02748.15 KFP01604.1 - 0.27 11.2 3.4 10 6.1 0.1 3.2 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zinc_ribbon_15 PF17032.5 KFP01604.1 - 0.31 11.8 2.7 1.1 10.0 0.6 2.2 1 1 1 2 2 2 0 zinc-ribbon family zf-Di19 PF05605.12 KFP01604.1 - 0.54 10.6 9.0 0.14 12.5 0.9 2.5 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Elf1 PF05129.13 KFP01604.1 - 0.97 9.5 3.3 0.85 9.7 0.6 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-AN1 PF01428.16 KFP01604.1 - 1.3 9.2 7.0 19 5.5 0.1 3.2 3 0 0 3 3 3 0 AN1-like Zinc finger HNH_5 PF14279.6 KFP01604.1 - 1.9 8.4 5.2 27 4.7 0.1 3.3 3 0 0 3 3 3 0 HNH endonuclease zf_C2H2_ZHX PF18387.1 KFP01604.1 - 1.9 8.2 9.1 15 5.3 0.2 3.3 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-trcl PF13451.6 KFP01604.1 - 2.2 8.2 5.6 2.4 8.1 0.2 2.6 2 1 1 3 3 3 0 Probable zinc-ribbon domain zf-C2H2_11 PF16622.5 KFP01604.1 - 2.9 7.7 15.7 2.4 8.0 1.0 3.7 4 0 0 4 4 3 0 zinc-finger C2H2-type zf-BED PF02892.15 KFP01604.1 - 3.5 7.7 16.3 4.8 7.3 0.7 3.5 1 1 1 2 2 2 0 BED zinc finger PriA_CRR PF18319.1 KFP01604.1 - 4.4 7.4 7.8 27 4.9 0.9 3.3 3 0 0 3 3 3 0 PriA DNA helicase Cys-rich region (CRR) domain zf-C2H2_6 PF13912.6 KFP01604.1 - 4.6 7.4 13.7 0.75 9.9 1.6 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KFP01604.1 - 6.1 7.5 8.0 19 5.9 0.6 3.3 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_12 PF18658.1 KFP01604.1 - 8.4 6.0 8.1 0.8 9.3 0.4 2.8 1 1 2 3 3 3 0 Zinc-finger C2H2-type DUF3694 PF12473.8 KFP01605.1 - 4.8e-37 128.0 0.2 2e-36 126.0 0.2 1.8 1 1 0 1 1 1 1 Kinesin protein 7tm_1 PF00001.21 KFP01606.1 - 1.8e-39 135.7 18.9 2.7e-39 135.1 18.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP01606.1 - 6.4e-08 32.7 11.9 6.4e-08 32.7 11.9 1.8 2 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP01606.1 - 3e-06 27.1 19.4 3e-06 27.1 19.4 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Orf78 PF06024.12 KFP01606.1 - 1.8 8.9 0.0 1.8 8.9 0.0 3.0 3 1 1 4 4 4 0 Orf78 (ac78) CS PF04969.16 KFP01608.1 - 2.7e-15 57.1 0.6 5.8e-15 56.1 0.2 1.7 2 0 0 2 2 2 1 CS domain Siah-Interact_N PF09032.11 KFP01608.1 - 4.4e-12 46.1 2.3 4.4e-12 46.1 2.3 2.5 2 1 0 2 2 2 1 Siah interacting protein, N terminal SGS PF05002.15 KFP01608.1 - 1.2e-06 28.6 2.6 2.5e-06 27.5 2.6 1.5 1 0 0 1 1 1 1 SGS domain Pih1_fungal_CS PF18482.1 KFP01608.1 - 0.26 11.8 4.4 0.18 12.3 0.6 2.4 2 1 1 3 3 3 0 Fungal Pih1 CS domain Ribosomal_S14 PF00253.21 KFP01609.1 - 5.7e-20 70.8 0.6 5.7e-20 70.8 0.6 2.0 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e fn3 PF00041.21 KFP01610.1 - 1.8e-117 383.9 24.4 2.1e-15 56.8 0.0 9.3 9 0 0 9 9 9 9 Fibronectin type III domain Fibrinogen_C PF00147.18 KFP01610.1 - 5.6e-81 271.6 8.0 1e-80 270.7 8.0 1.5 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain EGF_Tenascin PF18720.1 KFP01610.1 - 8.7e-26 89.5 86.4 9.6e-12 44.7 17.7 5.3 5 0 0 5 5 4 4 Tenascin EGF domain Pur_ac_phosph_N PF16656.5 KFP01610.1 - 3.1e-17 62.9 20.0 0.0028 18.2 0.0 9.4 7 3 0 7 7 7 5 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFP01610.1 - 1.8e-13 50.7 0.0 0.0079 16.5 0.1 7.4 8 0 0 8 8 8 2 Interferon-alpha/beta receptor, fibronectin type III EGF_2 PF07974.13 KFP01610.1 - 1.1e-11 44.9 94.6 0.00042 20.6 12.3 5.8 6 0 0 6 6 5 5 EGF-like domain fn3_2 PF16893.5 KFP01610.1 - 1e-06 28.8 1.9 4.6 7.5 0.0 6.6 7 0 0 7 7 7 1 Fibronectin type III domain DUF4998 PF16389.5 KFP01610.1 - 2e-05 24.3 0.0 0.26 10.8 0.0 4.5 5 0 0 5 5 5 2 Domain of unknown function DUF4959 PF16323.5 KFP01610.1 - 4.8e-05 23.6 0.1 0.45 10.8 0.0 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4959) DUF2369 PF10179.9 KFP01610.1 - 0.00023 21.5 4.4 60 4.1 0.0 6.7 7 1 0 7 7 7 0 Uncharacterised conserved protein (DUF2369) Big_10 PF17964.1 KFP01610.1 - 0.0027 17.7 8.8 4 7.4 0.1 5.1 5 1 1 6 6 6 1 Bacterial Ig domain CarboxypepD_reg PF13620.6 KFP01610.1 - 0.036 14.3 8.4 0.28 11.5 0.3 4.5 4 0 0 4 4 4 0 Carboxypeptidase regulatory-like domain Lzipper-MIP1 PF14389.6 KFP01610.1 - 0.041 14.2 0.2 0.098 13.0 0.2 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 EGF PF00008.27 KFP01610.1 - 0.097 13.0 73.5 0.25 11.7 9.2 5.8 5 0 0 5 5 5 0 EGF-like domain TSC22 PF01166.18 KFP01610.1 - 0.24 11.8 0.3 0.57 10.5 0.3 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family WD40 PF00400.32 KFP01611.1 - 1.8e-22 79.2 4.4 0.034 15.0 0.0 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat zf-C3HC4_2 PF13923.6 KFP01611.1 - 7.7e-16 57.6 10.8 2e-15 56.4 10.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP01611.1 - 5.8e-10 38.9 12.1 1.7e-09 37.4 12.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP01611.1 - 1.4e-08 34.5 7.6 3.5e-08 33.2 7.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP01611.1 - 4.2e-08 33.1 7.3 1.5e-07 31.3 7.3 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFP01611.1 - 5.5e-08 33.0 10.1 5.5e-08 33.0 10.1 2.8 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.6 KFP01611.1 - 6.8e-08 32.3 10.7 6.8e-08 32.3 10.7 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFP01611.1 - 1.5e-06 28.2 10.9 5.7e-06 26.4 10.9 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING ANAPC4_WD40 PF12894.7 KFP01611.1 - 0.00017 21.8 0.4 2.3 8.5 0.0 4.3 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFP01611.1 - 0.00034 20.1 0.0 0.0019 17.6 0.0 2.1 1 1 1 2 2 2 1 WD40-like domain zf_C2H2_10 PF18414.1 KFP01611.1 - 0.0064 16.0 0.6 0.14 11.8 0.1 2.7 2 0 0 2 2 2 1 C2H2 type zinc-finger zf-rbx1 PF12678.7 KFP01611.1 - 0.0069 16.6 10.5 0.0069 16.6 10.5 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFP01611.1 - 0.011 15.6 9.7 0.06 13.2 9.5 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KFP01611.1 - 0.012 15.4 10.3 0.062 13.1 10.7 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 KFP01611.1 - 0.024 14.7 4.2 0.082 13.1 4.2 1.9 1 0 0 1 1 1 0 zinc RING finger of MSL2 DZR PF12773.7 KFP01611.1 - 0.1 12.6 5.4 0.4 10.8 5.4 2.0 1 0 0 1 1 1 0 Double zinc ribbon zf-Nse PF11789.8 KFP01611.1 - 2.6 7.9 10.6 0.39 10.6 5.7 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit AAA_23 PF13476.6 KFP01611.1 - 4.7 7.7 6.2 11 6.5 6.2 1.6 1 0 0 1 1 1 0 AAA domain Laminin_G_3 PF13385.6 KFP01612.1 - 1.1e-17 64.6 0.2 2.1e-17 63.6 0.2 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Peptidase_M43 PF05572.13 KFP01612.1 - 1.3e-11 44.6 0.2 1.3e-11 44.6 0.2 2.0 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Sushi PF00084.20 KFP01612.1 - 9.9e-08 32.5 61.0 3.5e-06 27.5 1.4 8.9 9 1 0 9 9 9 4 Sushi repeat (SCR repeat) DUF4215 PF13948.6 KFP01612.1 - 3.2e-05 24.3 1.4 3.2e-05 24.3 1.4 6.2 6 0 0 6 6 6 1 Domain of unknown function (DUF4215) Reprolysin_3 PF13582.6 KFP01612.1 - 0.015 15.8 0.6 0.028 14.9 0.6 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Laminin_G_2 PF02210.24 KFP01612.1 - 0.019 15.6 0.0 0.039 14.5 0.0 1.5 1 0 0 1 1 1 0 Laminin G domain DUF4953 PF16313.5 KFP01612.1 - 0.088 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M66 PF10462.9 KFP01612.1 - 0.23 10.4 1.7 0.4 9.6 1.7 1.3 1 0 0 1 1 1 0 Peptidase M66 Annexin_like PF18411.1 KFP01613.1 - 2.5e-49 165.5 0.0 5.3e-49 164.4 0.0 1.6 1 0 0 1 1 1 1 Annexin-like domain FXa_inhibition PF14670.6 KFP01613.1 - 8.2e-13 48.4 33.9 3e-09 37.0 3.5 4.0 3 0 0 3 3 3 3 Coagulation Factor Xa inhibitory site Tme5_EGF_like PF09064.10 KFP01613.1 - 0.00086 19.2 1.5 0.00086 19.2 1.5 2.9 2 0 0 2 2 2 1 Thrombomodulin like fifth domain, EGF-like ASTN_2_hairpin PF18577.1 KFP01613.1 - 0.0017 18.4 0.1 0.0045 17.1 0.1 1.7 1 0 0 1 1 1 1 Astrotactin-2 C-terminal beta-hairpin domain MACPF PF01823.19 KFP01613.1 - 0.0023 18.1 0.2 0.011 15.9 0.0 2.0 2 0 0 2 2 2 1 MAC/Perforin domain UPF0560 PF10577.9 KFP01613.1 - 0.075 11.5 0.4 0.14 10.6 0.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 MACPF PF01823.19 KFP01614.1 - 2.3e-06 27.8 0.0 4.6e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 MAC/Perforin domain Sec16_C PF12931.7 KFP01615.1 - 1.6e-43 149.5 0.1 4.5e-43 148.0 0.1 1.6 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KFP01615.1 - 4.9e-09 36.8 0.0 1.1e-08 35.7 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region zf-nanos PF05741.13 KFP01615.1 - 0.087 13.1 0.2 0.45 10.8 0.1 2.3 2 0 0 2 2 2 0 Nanos RNA binding domain RasGEF PF00617.19 KFP01616.1 - 4.9e-53 179.9 0.4 3e-52 177.4 0.2 2.0 1 1 1 2 2 2 1 RasGEF domain PH PF00169.29 KFP01616.1 - 1.8e-09 38.0 0.5 3.6e-09 37.1 0.1 1.8 2 0 0 2 2 2 1 PH domain CRISPR_Cas9_WED PF18061.1 KFP01616.1 - 0.0062 16.6 0.1 0.012 15.7 0.1 1.4 1 0 0 1 1 1 1 CRISPR-Cas9 WED domain Fibrinogen_C PF00147.18 KFP01617.1 - 1e-72 244.5 10.4 1.4e-72 244.1 10.4 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain ZirS_C PF16583.5 KFP01617.1 - 0.012 15.2 0.2 0.13 11.8 0.1 2.1 2 0 0 2 2 2 0 Zinc-regulated secreted antivirulence protein C-terminal domain Fer4_NifH PF00142.18 KFP01617.1 - 0.27 10.7 0.9 0.4 10.1 0.9 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SlyX PF04102.12 KFP01617.1 - 1.6 9.4 5.5 7.5 7.3 0.8 2.9 1 1 0 2 2 2 0 SlyX ZapB PF06005.12 KFP01617.1 - 3.1 8.3 9.0 3.2 8.2 2.6 2.3 2 0 0 2 2 2 0 Cell division protein ZapB Fam20C PF06702.12 KFP01618.1 - 1.1e-86 290.1 0.0 1.7e-86 289.6 0.0 1.3 1 0 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 FAM198 PF15051.6 KFP01618.1 - 0.0019 17.2 0.0 0.0034 16.3 0.0 1.4 1 0 0 1 1 1 1 FAM198 protein HipA_C PF07804.12 KFP01618.1 - 0.16 11.6 0.0 1.8 8.2 0.0 2.3 3 0 0 3 3 3 0 HipA-like C-terminal domain Torsin PF06309.11 KFP01619.1 - 2.2e-46 157.0 1.3 4.2e-46 156.2 0.7 1.8 2 0 0 2 2 2 1 Torsin AAA PF00004.29 KFP01619.1 - 0.00012 22.4 0.0 0.00019 21.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFP01619.1 - 0.00024 21.4 0.1 0.044 14.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFP01619.1 - 0.0012 19.3 0.0 0.0032 17.9 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KFP01619.1 - 0.0027 18.1 0.0 0.0046 17.3 0.0 1.4 1 0 0 1 1 1 1 RNA helicase PIF1 PF05970.14 KFP01619.1 - 0.0055 15.9 0.1 0.032 13.4 0.1 1.9 1 1 0 1 1 1 1 PIF1-like helicase NACHT PF05729.12 KFP01619.1 - 0.018 15.0 0.2 0.045 13.7 0.2 1.9 1 1 0 1 1 1 0 NACHT domain SEFIR PF08357.11 KFP01619.1 - 0.038 14.3 0.1 0.13 12.6 0.0 1.9 1 1 1 2 2 2 0 SEFIR domain APS_kinase PF01583.20 KFP01619.1 - 0.15 12.0 0.0 0.46 10.4 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase PI3K_P85_iSH2 PF16454.5 KFP01619.1 - 0.23 11.0 2.3 0.18 11.4 0.3 1.6 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Pkinase_Tyr PF07714.17 KFP01620.1 - 2.5e-97 325.2 0.0 3.9e-97 324.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP01620.1 - 7.7e-47 159.9 0.0 1.4e-46 159.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain F_actin_bind PF08919.10 KFP01620.1 - 7.3e-28 96.9 0.0 1.6e-27 95.8 0.0 1.6 1 0 0 1 1 1 1 F-actin binding SH2 PF00017.24 KFP01620.1 - 2.2e-24 85.3 0.2 5.1e-24 84.2 0.2 1.7 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFP01620.1 - 3.6e-12 45.7 0.0 6.7e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP01620.1 - 4.7e-07 29.6 0.0 1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP01620.1 - 5.3e-07 29.2 0.0 1.1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFP01620.1 - 3.1e-05 24.2 0.6 9.2e-05 22.6 0.6 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain Haspin_kinase PF12330.8 KFP01620.1 - 0.0035 16.3 0.0 0.0071 15.3 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain SH3_6 PF12913.7 KFP01620.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 SH3 domain (SH3b1 type) RGS12_us1 PF16613.5 KFP01620.1 - 1.2 9.5 8.0 0.12 12.7 2.7 2.1 2 0 0 2 2 2 0 Unstructured region of RGS12 MBOAT PF03062.19 KFP01621.1 - 1.5e-56 192.3 36.1 2.2e-56 191.7 36.1 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family RETICULATA-like PF11891.8 KFP01621.1 - 0.019 14.8 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein RETICULATA-related BamHI PF02923.15 KFP01621.1 - 0.18 11.5 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease BamHI Ax_dynein_light PF10211.9 KFP01622.1 - 8.6e-10 38.9 11.6 6.9e-09 35.9 9.6 2.4 2 0 0 2 2 2 1 Axonemal dynein light chain Fungal_trans_2 PF11951.8 KFP01622.1 - 0.018 13.9 1.4 0.034 13.0 1.4 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain COG2 PF06148.11 KFP01622.1 - 0.34 11.0 6.5 14 5.8 0.0 2.9 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Peptidase_S46 PF10459.9 KFP01622.1 - 0.81 8.3 3.5 1.1 7.8 3.5 1.1 1 0 0 1 1 1 0 Peptidase S46 Band_7 PF01145.25 KFP01623.1 - 3.3e-26 92.4 0.0 4e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KFP01623.1 - 0.0036 17.0 0.3 0.0059 16.3 0.3 1.2 1 0 0 1 1 1 1 SPFH domain-Band 7 family GatB_N PF02934.15 KFP01623.1 - 0.013 14.9 0.1 0.016 14.6 0.1 1.1 1 0 0 1 1 1 0 GatB/GatE catalytic domain PRTP PF01366.18 KFP01623.1 - 0.033 12.3 0.2 0.039 12.0 0.2 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Synapsin PF02078.16 KFP01623.1 - 0.053 13.8 0.1 0.11 12.8 0.1 1.5 1 1 0 1 1 1 0 Synapsin, N-terminal domain OST-HTH PF12872.7 KFP01624.1 - 2.4e-05 24.1 0.0 7.3e-05 22.5 0.0 1.8 3 0 0 3 3 3 1 OST-HTH/LOTUS domain MAP65_ASE1 PF03999.12 KFP01624.1 - 0.15 10.7 0.2 0.17 10.5 0.2 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) TUDOR PF00567.24 KFP01625.1 - 2.7e-14 53.2 0.1 5.6e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 Tudor domain FAM163 PF15069.6 KFP01626.1 - 2e-65 220.2 1.0 2.2e-65 220.0 1.0 1.0 1 0 0 1 1 1 1 FAM163 family DUF4006 PF13179.6 KFP01626.1 - 0.01 15.7 0.5 0.017 15.0 0.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF4006) PRIMA1 PF16101.5 KFP01626.1 - 0.12 12.5 0.3 0.12 12.5 0.3 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 EphA2_TM PF14575.6 KFP01626.1 - 0.17 12.8 0.0 0.21 12.5 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DHDPS PF00701.22 KFP01627.1 - 2.3e-46 157.8 0.0 2.7e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family dsrm PF00035.26 KFP01628.1 - 3.1e-23 82.3 0.2 3.2e-11 43.8 0.1 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif Helicase_C PF00271.31 KFP01628.1 - 3.2e-15 56.4 0.0 7.9e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFP01628.1 - 2.8e-07 30.5 0.0 1.6e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase HA2 PF04408.23 KFP01628.1 - 2.8e-05 24.4 0.0 7.6e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) AAA_14 PF13173.6 KFP01628.1 - 0.0059 16.6 0.1 0.053 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KFP01628.1 - 0.0063 15.6 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 KFP01628.1 - 0.01 15.8 0.1 0.2 11.6 0.1 2.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Dicer_dimer PF03368.14 KFP01628.1 - 0.017 15.2 0.0 0.16 12.1 0.0 2.6 3 0 0 3 3 3 0 Dicer dimerisation domain PhoH PF02562.16 KFP01628.1 - 0.055 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.6 KFP01628.1 - 0.078 13.3 0.0 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 KFP01628.1 - 0.085 12.2 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 KFP01628.1 - 0.097 12.9 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ploopntkinase2 PF18747.1 KFP01628.1 - 0.18 11.1 0.0 0.47 9.7 0.0 1.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase2 OB_NTP_bind PF07717.16 KFP01629.1 - 8.6e-14 51.7 0.0 1.5e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Rh5 PF18515.1 KFP01630.1 - 0.0034 16.7 0.3 0.0049 16.2 0.3 1.2 1 0 0 1 1 1 1 Rh5 coiled-coil domain Laminin_II PF06009.12 KFP01630.1 - 0.0035 17.4 14.8 0.19 11.7 1.6 3.1 1 1 2 3 3 3 2 Laminin Domain II AAA_13 PF13166.6 KFP01630.1 - 0.013 14.2 14.6 0.016 13.8 14.6 1.0 1 0 0 1 1 1 0 AAA domain CK2S PF15011.6 KFP01630.1 - 0.027 14.4 3.4 0.065 13.1 0.9 2.4 2 1 0 2 2 2 0 Casein Kinase 2 substrate GET2 PF08690.10 KFP01630.1 - 0.034 13.8 12.8 0.045 13.4 7.4 2.0 2 0 0 2 2 2 0 GET complex subunit GET2 CODH_A_N PF18537.1 KFP01630.1 - 0.06 13.4 3.3 2.2 8.4 0.5 2.9 2 1 0 3 3 2 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain Orthopox_B11R PF07033.11 KFP01630.1 - 0.073 12.9 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 Orthopoxvirus B11R protein TRAF_BIRC3_bd PF16673.5 KFP01630.1 - 0.11 12.3 5.8 0.73 9.7 0.1 3.2 3 1 1 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain PHM7_cyt PF14703.6 KFP01630.1 - 0.15 12.3 4.5 1.4 9.1 4.0 2.1 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Cas_DxTHG PF09455.10 KFP01630.1 - 0.15 11.6 3.6 0.2 11.2 3.6 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family DUF3450 PF11932.8 KFP01630.1 - 0.24 10.7 20.5 1.5 8.0 1.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) LMBR1 PF04791.16 KFP01630.1 - 0.37 9.6 4.0 0.45 9.4 4.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein BLOC1_2 PF10046.9 KFP01630.1 - 0.39 11.1 15.7 2 8.8 1.2 3.8 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 KFP01630.1 - 0.42 10.9 8.9 2.6 8.4 0.3 3.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) SesA PF17107.5 KFP01630.1 - 0.45 10.7 9.0 12 6.1 0.6 3.5 1 1 2 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Alanine_zipper PF11839.8 KFP01630.1 - 0.48 10.8 34.7 0.66 10.4 12.5 3.1 3 1 1 4 4 4 0 Alanine-zipper, major outer membrane lipoprotein DUF1664 PF07889.12 KFP01630.1 - 1.3 9.1 11.1 2.8 8.0 1.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KFP01630.1 - 1.5 9.3 7.6 9.8 6.7 0.3 3.6 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) BST2 PF16716.5 KFP01630.1 - 1.6 9.4 14.0 0.33 11.5 1.7 3.0 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 Med9 PF07544.13 KFP01630.1 - 1.6 8.9 8.6 4.4 7.5 0.3 3.4 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Seryl_tRNA_N PF02403.22 KFP01630.1 - 2.3 8.5 20.7 3.8 7.8 2.4 3.2 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FUSC PF04632.12 KFP01630.1 - 2.4 6.6 5.4 3 6.3 5.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family V_ATPase_I PF01496.19 KFP01630.1 - 2.4 5.9 9.0 3.8 5.3 8.7 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.12 KFP01630.1 - 2.7 8.0 21.3 0.76 9.8 11.9 2.9 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein CC2-LZ PF16516.5 KFP01630.1 - 3.3 8.1 12.8 1.1 9.6 3.5 2.9 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator APG6_N PF17675.1 KFP01630.1 - 3.5 8.2 19.1 0.6 10.6 7.2 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region CCDC-167 PF15188.6 KFP01630.1 - 4.6 7.7 7.3 1.1 9.6 0.2 2.8 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 SlyX PF04102.12 KFP01630.1 - 5.1 7.8 11.2 5.6 7.7 0.7 3.0 2 2 0 2 2 2 0 SlyX CHD5 PF04420.14 KFP01630.1 - 6.4 6.6 5.1 1.5 8.6 1.3 2.0 2 1 0 2 2 2 0 CHD5-like protein DNA_ligase_A_N PF04675.14 KFP01630.1 - 6.8 7.0 9.2 3.2 8.1 5.3 2.1 1 1 1 2 2 2 0 DNA ligase N terminus YlqD PF11068.8 KFP01630.1 - 9.6 6.6 14.5 1.2 9.5 6.3 2.4 1 1 2 3 3 3 0 YlqD protein HisKA_3 PF07730.13 KFP01630.1 - 9.7 6.8 15.3 7 7.2 3.6 4.3 1 1 3 4 4 4 0 Histidine kinase Laminin_EGF PF00053.24 KFP01631.1 - 5e-31 106.6 105.4 3.1e-10 40.0 12.1 7.8 7 0 0 7 7 7 6 Laminin EGF domain Laminin_B PF00052.18 KFP01631.1 - 1.4e-24 86.5 0.0 4.4e-24 84.9 0.0 1.9 1 0 0 1 1 1 1 Laminin B (Domain IV) Sec34 PF04136.15 KFP01631.1 - 4.4 7.2 11.6 3.6 7.5 2.0 3.9 3 1 0 3 3 3 0 Sec34-like family CTP_transf_like PF01467.26 KFP01632.1 - 9e-16 58.4 0.0 1.5e-14 54.4 0.0 2.1 1 1 0 1 1 1 1 Cytidylyltransferase-like SH3_1 PF00018.28 KFP01633.1 - 2.3e-28 97.5 0.0 7.3e-16 57.5 0.0 2.9 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KFP01633.1 - 6.4e-24 83.6 0.3 6.9e-13 48.2 0.0 3.3 3 0 0 3 3 3 2 Variant SH3 domain TPR_1 PF00515.28 KFP01633.1 - 2.6e-18 65.0 3.0 9.6e-05 22.0 0.2 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat SH3_2 PF07653.17 KFP01633.1 - 2.4e-17 62.4 0.0 8.5e-11 41.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain TPR_2 PF07719.17 KFP01633.1 - 2.5e-16 58.4 3.5 0.002 18.1 0.3 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFP01633.1 - 2.4e-11 43.8 1.3 0.00045 20.5 0.1 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat PB1 PF00564.24 KFP01633.1 - 3e-09 36.7 0.2 6.4e-09 35.6 0.2 1.6 1 0 0 1 1 1 1 PB1 domain TPR_8 PF13181.6 KFP01633.1 - 1.2e-07 31.3 0.6 0.028 14.6 0.0 3.8 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFP01633.1 - 4.9e-07 29.3 0.8 0.0039 17.1 0.0 4.0 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFP01633.1 - 6.4e-06 25.9 0.4 0.81 9.6 0.0 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFP01633.1 - 0.00077 20.1 0.2 0.088 13.5 0.0 3.4 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFP01633.1 - 0.0016 19.0 2.0 24 5.9 0.1 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFP01633.1 - 0.0071 16.6 0.1 3.5 8.2 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Cobl PF09469.10 KFP01633.1 - 0.011 16.0 0.1 0.032 14.5 0.1 1.7 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain TPR_14 PF13428.6 KFP01633.1 - 0.013 16.3 1.8 11 7.2 0.1 4.0 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFP01633.1 - 0.015 15.5 0.8 6.5 7.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat RBD PF02196.15 KFP01633.1 - 0.041 13.9 0.0 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 Raf-like Ras-binding domain RINT1_TIP1 PF04437.13 KFP01633.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 RINT-1 / TIP-1 family P16-Arc PF04699.14 KFP01634.1 - 1.3e-47 162.0 0.1 1.4e-47 161.9 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 KFP01634.1 - 0.0036 17.6 0.0 0.0049 17.2 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family RasGEF PF00617.19 KFP01635.1 - 4.3e-60 202.9 1.8 8.2e-60 202.0 1.8 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KFP01635.1 - 2.2e-18 66.4 1.4 6.4e-18 64.9 0.1 2.5 3 0 0 3 3 3 1 RasGEF N-terminal motif RA PF00788.23 KFP01635.1 - 2.3e-13 50.6 0.1 5e-12 46.3 0.0 3.0 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain DUF5423 PF17461.2 KFP01635.1 - 4.4 6.1 16.5 6.6 5.5 16.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Glyco_transf_25 PF01755.17 KFP01636.1 - 5.5e-39 134.1 0.0 7.6e-38 130.4 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_tranf_2_4 PF13704.6 KFP01636.1 - 3e-19 69.3 0.4 1e-18 67.6 0.4 2.0 1 0 0 1 1 1 1 Glycosyl transferase family 2 Anp1 PF03452.14 KFP01636.1 - 1.8e-06 27.6 0.0 9.7e-06 25.2 0.0 2.1 1 1 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 KFP01636.1 - 8.5e-05 22.4 0.1 0.003 17.4 0.1 2.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 Chordopox_A30L PF06015.12 KFP01636.1 - 0.0046 16.8 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Chordopoxvirus A30L protein IF4E PF01652.18 KFP01636.1 - 0.037 13.8 0.0 0.082 12.7 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic initiation factor 4E CAP59_mtransfer PF11735.8 KFP01636.1 - 0.091 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 Sen15 PF09631.10 KFP01637.1 - 3.9e-25 88.1 0.0 5e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein DUF4612 PF15389.6 KFP01638.1 - 4.8e-19 69.5 3.1 5.2e-19 69.4 3.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4612) Glyco_hydro_47 PF01532.20 KFP01639.1 - 5.6e-115 384.8 0.0 1.1e-114 383.9 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 KFP01639.1 - 4.3e-12 45.9 0.1 9.1e-12 44.8 0.1 1.5 1 0 0 1 1 1 1 PA domain Glyco_hydro_127 PF07944.12 KFP01639.1 - 0.14 10.7 0.0 0.24 9.8 0.0 1.3 1 0 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 Clathrin_H_link PF13838.6 KFP01640.1 - 0.056 13.4 1.1 0.088 12.7 0.1 1.9 2 0 0 2 2 2 0 Clathrin-H-link DUF3970 PF13113.6 KFP01640.1 - 0.12 12.6 0.5 7.9 6.8 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3970) RAWUL PF16207.5 KFP01641.1 - 6.3e-30 103.7 0.2 1.4e-29 102.6 0.2 1.6 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 KFP01641.1 - 4.8e-16 58.3 10.3 8.1e-16 57.6 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP01641.1 - 5.6e-10 38.9 10.4 1e-09 38.1 10.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP01641.1 - 5.4e-09 36.2 8.5 9.2e-09 35.5 8.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFP01641.1 - 6.2e-08 32.4 7.9 9.3e-08 31.8 7.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP01641.1 - 5.6e-06 26.3 8.0 1.1e-05 25.3 8.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP01641.1 - 1.6e-05 24.7 8.5 3e-05 23.9 8.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFP01641.1 - 4.9e-05 23.4 7.6 9.6e-05 22.5 7.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KFP01641.1 - 0.00021 21.1 5.5 0.00036 20.3 5.5 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KFP01641.1 - 0.00023 20.9 6.6 0.00048 19.8 6.6 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KFP01641.1 - 0.001 18.9 3.7 0.0018 18.1 3.7 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KFP01641.1 - 0.0015 18.7 7.1 0.0046 17.2 7.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_5 PF17121.5 KFP01641.1 - 0.035 14.0 7.1 0.34 10.8 7.4 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 KFP01641.1 - 0.042 13.9 1.9 0.14 12.3 1.9 1.9 1 0 0 1 1 1 0 Zinc-binding RING-finger Prok-RING_4 PF14447.6 KFP01641.1 - 0.066 13.1 8.4 0.9 9.4 8.8 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFP01641.1 - 0.21 11.6 2.5 0.43 10.7 2.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KFP01641.1 - 0.39 10.5 4.6 0.95 9.3 4.6 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-MIZ PF02891.20 KFP01641.1 - 0.76 9.6 6.8 1.5 8.7 6.8 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C4_Topoisom PF01396.19 KFP01641.1 - 2.1 8.2 5.1 0.27 11.1 0.9 1.7 2 0 0 2 2 1 0 Topoisomerase DNA binding C4 zinc finger TRM PF02005.16 KFP01642.1 - 1.3e-68 231.9 4.6 1.6e-57 195.4 1.1 2.8 2 1 0 3 3 3 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 KFP01642.1 - 0.0049 16.6 0.2 0.012 15.4 0.2 1.6 1 1 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.6 KFP01642.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KFP01642.1 - 0.12 11.9 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain MdoG PF04349.12 KFP01643.1 - 0.18 10.7 1.1 0.2 10.5 1.1 1.0 1 0 0 1 1 1 0 Periplasmic glucan biosynthesis protein, MdoG PIN_4 PF13638.6 KFP01644.1 - 4.2e-31 107.9 0.1 9.5e-31 106.8 0.1 1.6 1 0 0 1 1 1 1 PIN domain PIN_12 PF16289.5 KFP01644.1 - 0.0016 18.9 1.1 0.0073 16.8 0.0 2.4 2 1 1 3 3 3 1 PIN domain PIN_9 PF18477.1 KFP01644.1 - 0.0049 17.2 0.4 0.032 14.5 0.1 2.6 2 1 0 2 2 2 1 PIN like domain Mitofilin PF09731.9 KFP01644.1 - 0.055 12.3 0.2 0.087 11.7 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Cnl2_NKP2 PF09447.10 KFP01644.1 - 0.063 13.4 0.1 1.6 9.0 0.0 3.0 3 0 0 3 3 3 0 Cnl2/NKP2 family protein Kelch_1 PF01344.25 KFP01646.1 - 7e-86 281.6 9.5 1.3e-14 53.5 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFP01646.1 - 2e-50 167.5 2.4 2.4e-10 40.3 0.0 6.4 1 1 5 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KFP01646.1 - 8e-39 131.2 8.2 1.6e-08 34.6 0.1 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP01646.1 - 1.1e-38 129.7 1.6 9.8e-05 22.2 0.1 6.8 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 KFP01646.1 - 5.9e-32 109.4 3.0 6.3e-07 29.3 0.0 6.1 5 1 1 6 6 6 5 Galactose oxidase, central domain BTB PF00651.31 KFP01646.1 - 9.4e-27 93.5 0.5 1.4e-26 92.9 0.5 1.3 1 0 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.6 KFP01646.1 - 8.8e-17 60.7 4.9 0.003 17.5 0.0 6.2 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 KFP01646.1 - 3.1e-11 43.3 0.1 1.6e-10 41.0 0.0 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch XPA_C PF05181.12 KFP01646.1 - 0.2 11.7 3.9 19 5.3 0.0 4.1 5 0 0 5 5 5 0 XPA protein C-terminus PQQ_3 PF13570.6 KFP01646.1 - 3 8.4 9.2 10 6.8 0.2 4.5 5 0 0 5 5 5 0 PQQ-like domain I-set PF07679.16 KFP01647.1 - 0 2164.3 0.0 5.9e-21 74.3 0.1 42.1 42 1 0 42 42 41 41 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP01647.1 - 0 1950.6 74.1 1.5e-16 60.7 0.0 42.1 41 1 0 41 41 41 41 Immunoglobulin domain Ig_2 PF13895.6 KFP01647.1 - 0 1366.0 32.9 4.7e-13 49.3 0.0 41.9 41 0 0 41 41 41 40 Immunoglobulin domain ig PF00047.25 KFP01647.1 - 0 1101.9 0.0 4.2e-10 39.6 0.1 42.7 41 2 0 41 41 41 41 Immunoglobulin domain V-set PF07686.17 KFP01647.1 - 6e-131 428.6 102.6 0.00053 20.1 0.1 67.7 45 30 6 51 51 51 27 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP01647.1 - 1e-111 365.3 48.5 0.00042 20.3 0.0 39.3 40 0 0 40 40 40 25 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFP01647.1 - 9.1e-88 287.7 0.0 0.086 12.4 0.0 40.8 44 0 0 44 44 42 15 Immunoglobulin domain Ig_5 PF16681.5 KFP01647.1 - 3.4e-80 264.5 0.0 0.0047 17.3 0.0 37.2 40 0 0 40 40 40 13 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain EGF_CA PF07645.15 KFP01647.1 - 3.6e-64 212.7 119.3 8.3e-13 48.3 6.2 10.4 9 0 0 9 9 9 8 Calcium-binding EGF domain Ig_4 PF16680.5 KFP01647.1 - 1e-59 198.7 0.0 0.28 11.5 0.0 33.9 39 0 0 39 39 35 8 T-cell surface glycoprotein CD3 delta chain TSP_1 PF00090.19 KFP01647.1 - 5.6e-58 193.0 136.3 6.2e-13 48.8 8.7 8.8 9 0 0 9 9 6 6 Thrombospondin type 1 domain G2F PF07474.12 KFP01647.1 - 2.3e-53 180.7 0.0 5.2e-53 179.6 0.0 1.7 1 0 0 1 1 1 1 G2F domain cEGF PF12662.7 KFP01647.1 - 2.8e-49 164.6 64.8 1.5e-11 44.0 1.5 10.4 9 0 0 9 9 9 8 Complement Clr-like EGF-like Izumo-Ig PF16706.5 KFP01647.1 - 2e-38 130.3 5.7 1.5 9.0 0.0 31.7 39 0 0 39 39 37 3 Izumo-like Immunoglobulin domain C1-set PF07654.15 KFP01647.1 - 2.2e-37 127.3 12.0 0.91 10.0 0.0 28.8 34 0 0 34 34 29 5 Immunoglobulin C1-set domain Receptor_2B4 PF11465.8 KFP01647.1 - 1.6e-30 105.5 0.0 5.9 7.2 0.0 26.3 32 0 0 32 32 30 2 Natural killer cell receptor 2B4 Ig_C17orf99 PF17736.1 KFP01647.1 - 3.4e-29 100.7 18.8 0.11 12.6 0.0 27.1 34 0 0 34 34 30 2 C17orf99 Ig domain V-set_CD47 PF08204.11 KFP01647.1 - 1.7e-20 73.3 0.8 23 5.0 0.0 21.9 28 1 1 29 29 25 0 CD47 immunoglobulin-like domain C2-set PF05790.15 KFP01647.1 - 4e-19 68.6 0.0 5.1 7.4 0.0 21.1 28 0 0 28 28 23 1 Immunoglobulin C2-set domain FXa_inhibition PF14670.6 KFP01647.1 - 1.6e-12 47.5 147.6 8.9e-07 29.1 9.3 11.3 11 1 1 12 12 10 6 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 KFP01647.1 - 1.7e-07 31.3 109.8 0.00026 21.1 7.7 9.5 8 0 0 8 8 8 5 EGF domain A2M PF00207.22 KFP01647.1 - 0.0016 18.2 2.6 53 3.8 0.1 7.3 9 0 0 9 9 8 0 Alpha-2-macroglobulin family ANAPC4_WD40 PF12894.7 KFP01647.1 - 0.024 14.9 0.0 7.8 6.9 0.0 4.5 4 0 0 4 4 3 0 Anaphase-promoting complex subunit 4 WD40 domain RGS PF00615.19 KFP01648.1 - 9.1e-37 125.9 1.6 1.2e-36 125.5 1.6 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Sas6_CC PF18594.1 KFP01648.1 - 0.025 14.4 0.3 0.057 13.2 0.3 1.6 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain RGS PF00615.19 KFP01649.1 - 1.3e-37 128.6 2.1 1.6e-37 128.4 2.1 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS-like PF09128.11 KFP01649.1 - 0.0045 16.7 0.1 0.0057 16.4 0.1 1.1 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain Gag_p19 PF02228.16 KFP01649.1 - 0.03 14.8 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 2 0 Major core protein p19 DUF4929 PF16283.5 KFP01649.1 - 0.036 13.1 0.1 0.045 12.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4929) NAD_binding_10 PF13460.6 KFP01650.1 - 2.2e-08 34.2 0.0 3.1e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding bZIP_1 PF00170.21 KFP01651.1 - 1.2e-10 41.3 15.8 2.4e-10 40.4 15.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFP01651.1 - 6.5e-06 26.1 14.3 6.5e-06 26.1 14.3 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFP01651.1 - 0.0047 17.4 10.2 0.0047 17.4 10.2 2.2 2 0 0 2 2 2 1 bZIP Maf transcription factor DUF3450 PF11932.8 KFP01651.1 - 2.9 7.1 7.2 0.35 10.1 2.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) PikAIV_N PF18605.1 KFP01651.1 - 2.9 7.5 5.9 0.62 9.7 1.3 2.2 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain OLF PF02191.16 KFP01652.1 - 1.5e-85 286.7 10.0 2.1e-85 286.3 10.0 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain Noelin-1 PF12308.8 KFP01652.1 - 0.0016 18.4 0.6 0.012 15.6 0.0 2.4 2 0 0 2 2 2 1 Neurogenesis glycoprotein Pkinase_Tyr PF07714.17 KFP01654.1 - 2.5e-85 285.9 0.0 3.3e-85 285.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP01654.1 - 2.9e-43 148.1 0.0 1.9e-41 142.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain F5_F8_type_C PF00754.25 KFP01654.1 - 0.00058 20.0 0.0 0.0071 16.5 0.0 2.3 2 0 0 2 2 2 1 F5/8 type C domain Haspin_kinase PF12330.8 KFP01654.1 - 0.023 13.6 0.0 0.043 12.7 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Shisa PF13908.6 KFP01654.1 - 0.094 13.0 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4834 PF16118.5 KFP01654.1 - 0.19 12.7 0.0 0.36 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) F5_F8_type_C PF00754.25 KFP01655.1 - 3.2e-14 53.1 0.1 3.8e-14 52.9 0.1 1.0 1 0 0 1 1 1 1 F5/8 type C domain UDPGP PF01704.18 KFP01656.1 - 2.4e-61 207.6 0.0 3e-61 207.3 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Pkinase PF00069.25 KFP01657.1 - 6.6e-25 88.0 0.0 1.6e-24 86.7 0.0 1.6 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP01657.1 - 4.1e-10 39.4 0.0 9e-10 38.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase RRM_1 PF00076.22 KFP01657.1 - 3.4e-08 33.2 0.0 6.6e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinase-like PF14531.6 KFP01657.1 - 6.3e-06 25.7 0.0 8.4e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 KFP01657.1 - 0.0086 15.7 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KFP01657.1 - 0.0094 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFP01657.1 - 0.022 14.3 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KFP01657.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4628 PF15429.6 KFP01658.1 - 8.1e-41 140.5 1.2 9e-41 140.4 1.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4628) PID PF00640.23 KFP01659.1 - 9.2e-30 103.5 1.0 9.2e-30 103.5 1.0 2.0 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) Phage_GPO PF05929.11 KFP01659.1 - 0.23 11.0 7.6 0.097 12.3 2.9 2.1 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase SIN1_PH PF16979.5 KFP01659.1 - 0.29 11.4 3.5 0.69 10.2 3.5 1.6 1 0 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology FAM194 PF14977.6 KFP01659.1 - 0.7 9.2 3.8 0.26 10.6 0.3 2.0 2 1 0 2 2 2 0 FAM194 protein CECR6_TMEM121 PF14997.6 KFP01660.1 - 2.5e-60 203.6 11.4 4.3e-60 202.9 11.4 1.3 1 0 0 1 1 1 1 CECR6/TMEM121 family DUF5083 PF16890.5 KFP01660.1 - 9.4e-05 22.2 1.3 9.4e-05 22.2 1.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5083) LIM PF00412.22 KFP01661.1 - 2.7e-13 49.9 2.3 2.9e-13 49.8 2.3 1.1 1 0 0 1 1 1 1 LIM domain zf_UBZ PF18439.1 KFP01661.1 - 3.9 7.2 7.4 0.35 10.5 1.1 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger LIM PF00412.22 KFP01662.1 - 7.2e-25 87.0 14.8 2.3e-14 53.4 4.0 2.2 2 0 0 2 2 2 2 LIM domain NinD PF17466.2 KFP01662.1 - 0.0098 16.0 13.8 0.22 11.6 0.1 3.4 2 1 1 3 3 3 2 Family of unknown function zf-CCHC_5 PF14787.6 KFP01662.1 - 0.013 15.2 0.0 0.013 15.2 0.0 3.6 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger YacG PF03884.14 KFP01662.1 - 0.018 14.8 8.4 3.5 7.4 0.5 3.5 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG Metallothio_Pro PF02069.16 KFP01662.1 - 0.034 14.4 6.2 2.7 8.3 0.8 2.6 2 0 0 2 2 2 0 Prokaryotic metallothionein Ribosomal_L37e PF01907.19 KFP01662.1 - 0.039 14.1 11.8 2 8.6 0.2 3.4 2 1 1 3 3 3 0 Ribosomal protein L37e Pea-VEAacid PF08111.11 KFP01662.1 - 0.082 13.2 2.6 15 6.2 0.2 2.7 2 0 0 2 2 2 0 Pea-VEAacid family Integrase_H2C2 PF17921.1 KFP01662.1 - 1.4 9.0 6.7 1.3 9.2 0.2 2.5 2 1 0 2 2 2 0 Integrase zinc binding domain zinc_ribbon_12 PF11331.8 KFP01662.1 - 1.8 8.5 7.3 2 8.3 2.0 2.4 2 0 0 2 2 2 0 Probable zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 KFP01662.1 - 1.8 8.6 11.9 0.2 11.6 4.2 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Mut7-C PF01927.16 KFP01662.1 - 3.8 7.6 6.6 12 6.0 1.3 2.4 2 1 0 2 2 2 0 Mut7-C RNAse domain zf_UBZ PF18439.1 KFP01662.1 - 3.9 7.2 25.9 0.65 9.6 1.1 4.4 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger MTA_R1 PF17226.2 KFP01663.1 - 2.7e-37 126.8 6.3 1.5e-34 118.0 1.9 2.7 2 0 0 2 2 2 2 MTA R1 domain BAH PF01426.18 KFP01663.1 - 1e-23 83.5 0.4 2e-23 82.6 0.2 1.6 2 0 0 2 2 2 1 BAH domain ELM2 PF01448.24 KFP01663.1 - 3e-13 50.3 0.2 1.5e-12 48.1 0.0 2.3 2 0 0 2 2 2 1 ELM2 domain GATA PF00320.27 KFP01663.1 - 8.8e-10 38.0 10.0 2.1e-09 36.8 10.0 1.7 1 0 0 1 1 1 1 GATA zinc finger Myb_DNA-binding PF00249.31 KFP01663.1 - 2.8e-06 27.4 0.1 6.9e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFP01663.1 - 0.017 15.0 0.3 0.017 15.0 0.3 2.1 2 0 0 2 2 2 0 Myb DNA-binding like Pacs-1 PF10254.9 KFP01664.1 - 3.6e-203 675.1 0.1 3.6e-203 675.1 0.1 1.6 2 0 0 2 2 2 1 PACS-1 cytosolic sorting protein CSRNP_N PF16019.5 KFP01664.1 - 5.7 6.8 8.2 0.19 11.6 0.8 2.2 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Longin PF13774.6 KFP01665.1 - 3.9e-23 81.3 0.1 5e-23 80.9 0.1 1.2 1 0 0 1 1 1 1 Regulated-SNARE-like domain EGF PF00008.27 KFP01666.1 - 1.1e-117 383.7 217.8 3.8e-10 39.9 6.5 15.3 15 0 0 15 15 15 15 EGF-like domain hEGF PF12661.7 KFP01666.1 - 1.7e-82 269.5 193.3 2e-07 31.4 3.8 17.0 16 0 0 16 16 15 15 Human growth factor-like EGF EGF_CA PF07645.15 KFP01666.1 - 8.6e-50 166.7 214.5 4.8e-08 33.1 6.1 15.2 11 4 4 15 15 15 13 Calcium-binding EGF domain EGF_2 PF07974.13 KFP01666.1 - 1.3e-22 79.8 244.0 0.0045 17.3 4.3 15.3 15 0 0 15 15 15 13 EGF-like domain EGF_3 PF12947.7 KFP01666.1 - 4.4e-15 55.6 204.7 3.1e-05 24.1 4.0 16.2 14 2 1 15 15 15 11 EGF domain FXa_inhibition PF14670.6 KFP01666.1 - 2.9e-08 33.8 198.0 0.097 13.0 4.6 15.2 5 4 10 15 15 15 8 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFP01666.1 - 2e-06 27.6 185.7 0.0016 18.3 0.6 17.8 16 4 0 16 16 16 10 Complement Clr-like EGF-like Phage_Orf51 PF06194.11 KFP01666.1 - 0.0021 18.0 0.0 1.8 8.7 0.0 3.6 4 0 0 4 4 4 1 Phage Conserved Open Reading Frame 51 EGF_MSP1_1 PF12946.7 KFP01666.1 - 0.0074 16.3 5.9 0.0074 16.3 5.9 14.6 15 1 0 15 15 15 7 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.11 KFP01666.1 - 0.03 14.6 4.6 0.03 14.6 4.6 15.3 13 2 2 15 15 15 0 Pvs28 EGF domain Laminin_EGF PF00053.24 KFP01666.1 - 6.2 7.1 198.5 6.4 7.0 6.7 14.5 5 4 9 14 14 14 0 Laminin EGF domain Ank_2 PF12796.7 KFP01667.1 - 4.8e-34 116.8 15.1 1.1e-12 48.4 1.2 4.2 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 KFP01667.1 - 2.4e-30 103.6 11.4 4.3e-07 30.1 0.0 6.9 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KFP01667.1 - 1.7e-26 91.9 11.8 1.2e-09 38.2 0.4 5.1 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP01667.1 - 9e-21 71.8 3.8 0.0058 17.1 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 KFP01667.1 - 1.5e-19 70.1 3.0 3.9e-06 27.3 0.3 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Lectin_C PF00059.21 KFP01669.1 - 5.1e-17 62.6 1.4 6.7e-17 62.2 1.4 1.2 1 0 0 1 1 1 1 Lectin C-type domain HMG_CoA_synt_C PF08540.10 KFP01670.1 - 5.6e-122 406.7 0.0 7.2e-122 406.4 0.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFP01670.1 - 3.9e-99 329.7 0.2 5.6e-99 329.2 0.2 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Abhydrolase_1 PF00561.20 KFP01670.1 - 0.012 15.2 0.1 0.012 15.2 0.1 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold ACP_syn_III PF08545.10 KFP01670.1 - 0.043 13.7 0.3 0.1 12.5 0.3 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 2-Hacid_dh_C PF02826.19 KFP01671.1 - 1.1e-59 200.8 0.0 1.8e-59 200.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFP01671.1 - 1e-37 128.8 0.0 2e-37 127.8 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain SMYLE_N PF18615.1 KFP01672.1 - 1.4e-175 584.5 0.2 1.4e-175 584.5 0.2 4.0 2 1 2 4 4 4 1 Short myomegalin-like EB1 binding proteins, N-terminal domain zf-AD PF07776.15 KFP01672.1 - 0.00082 19.6 1.5 0.00082 19.6 1.5 3.5 3 1 1 4 4 4 1 Zinc-finger associated domain (zf-AD) Cnd1 PF12717.7 KFP01672.1 - 0.0015 18.6 3.5 0.0015 18.6 3.5 3.2 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 NMT1_3 PF16868.5 KFP01672.1 - 0.077 12.4 0.2 0.28 10.5 0.0 1.9 2 0 0 2 2 2 0 NMT1-like family DUF211 PF02680.14 KFP01672.1 - 0.14 12.3 0.0 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 Olduvai PF06758.13 KFP01674.1 - 0.016 15.4 3.6 0.051 13.8 3.6 1.8 1 0 0 1 1 1 0 Olduvai domain AMPK1_CBM PF16561.5 KFP01675.1 - 3.8e-36 123.2 0.2 6.3e-36 122.5 0.2 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KFP01675.1 - 8.4e-28 96.5 2.9 1.5e-27 95.6 2.9 1.4 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 KFP01675.1 - 0.0026 18.1 0.0 0.0052 17.1 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) FMO-like PF00743.19 KFP01676.1 - 6e-250 830.2 0.0 6.7e-250 830.0 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFP01676.1 - 5.1e-15 55.5 0.1 9.6e-11 41.5 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFP01676.1 - 3.4e-13 49.5 0.0 7.5e-10 38.5 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFP01676.1 - 1.5e-08 34.2 0.1 5.8e-06 25.7 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KFP01676.1 - 1.9e-05 24.8 0.3 0.00049 20.3 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFP01676.1 - 6.7e-05 22.6 1.2 0.2 11.2 0.0 3.8 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KFP01676.1 - 0.00015 21.8 0.6 3.3 7.7 0.1 4.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KFP01676.1 - 0.00052 20.5 1.1 0.016 15.8 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFP01676.1 - 0.0044 15.8 0.8 1.6 7.3 0.2 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 KFP01676.1 - 0.015 14.4 1.7 1.6 7.7 0.1 2.8 3 0 0 3 3 3 0 FAD binding domain Thi4 PF01946.17 KFP01676.1 - 0.021 14.1 0.1 6.1 6.0 0.0 2.3 2 0 0 2 2 2 0 Thi4 family Prenylcys_lyase PF07156.14 KFP01676.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Prenylcysteine lyase FMO-like PF00743.19 KFP01677.1 - 1.8e-254 845.1 0.0 2e-254 844.9 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFP01677.1 - 2e-18 66.7 0.0 2.1e-13 50.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFP01677.1 - 4.7e-15 55.6 0.0 2.1e-11 43.6 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFP01677.1 - 3.2e-07 29.8 0.2 4.1e-05 22.9 0.0 3.1 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KFP01677.1 - 1.8e-06 28.1 0.0 7.1e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KFP01677.1 - 6.9e-06 26.1 0.9 0.12 12.3 0.1 4.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 KFP01677.1 - 9.3e-06 25.0 0.0 0.092 12.0 0.0 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.24 KFP01677.1 - 0.00019 21.2 1.2 0.21 11.1 0.0 3.2 2 1 1 4 4 4 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFP01677.1 - 0.00027 21.4 0.4 0.042 14.4 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFP01677.1 - 0.0013 17.5 0.4 0.12 11.1 0.1 2.5 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KFP01677.1 - 0.015 14.7 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Prenylcys_lyase PF07156.14 KFP01677.1 - 0.038 13.1 0.0 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 Prenylcysteine lyase FAD_binding_3 PF01494.19 KFP01677.1 - 0.052 12.8 0.2 0.66 9.2 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.24 KFP01677.1 - 0.067 12.3 0.1 5.7 5.9 0.0 2.6 3 0 0 3 3 3 0 FAD binding domain PAP2 PF01569.21 KFP01678.1 - 6.6e-21 74.5 3.3 1.1e-20 73.8 3.3 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KFP01678.1 - 2e-06 27.6 11.5 8.1e-06 25.7 11.5 1.9 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KFP01678.1 - 0.00049 20.6 2.6 0.00081 19.9 1.0 2.0 2 0 0 2 2 2 1 PAP2 superfamily C-terminal MNHE PF01899.16 KFP01678.1 - 4.4 7.0 9.2 3.7 7.3 4.3 2.2 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit RFC1 PF08519.12 KFP01679.1 - 0.05 13.8 0.0 0.061 13.5 0.0 1.2 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain AhpC-TSA PF00578.21 KFP01680.1 - 2e-12 47.1 0.0 3.7e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 KFP01680.1 - 1.1e-11 44.4 0.2 1.7e-11 43.8 0.2 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 KFP01680.1 - 0.00015 21.5 0.0 0.00026 20.7 0.0 1.3 1 0 0 1 1 1 1 Redoxin SAGA-Tad1 PF12767.7 KFP01681.1 - 1.1e-27 97.3 0.3 2.1e-15 57.1 0.1 2.2 1 1 1 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.14 KFP01681.1 - 0.012 15.4 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family TNF PF00229.18 KFP01683.1 - 2.6e-29 101.7 0.1 4.3e-29 101.0 0.1 1.4 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Sad1_UNC PF07738.13 KFP01684.1 - 4e-37 127.2 0.0 9.2e-37 126.0 0.0 1.7 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal dNK PF01712.19 KFP01684.1 - 0.0083 16.0 0.4 0.017 14.9 0.4 1.5 1 0 0 1 1 1 1 Deoxynucleoside kinase MbeD_MobD PF04899.12 KFP01684.1 - 0.099 12.8 4.9 0.28 11.3 4.9 1.8 1 0 0 1 1 1 0 MbeD/MobD like TetR_C_37 PF18665.1 KFP01684.1 - 0.12 13.0 0.8 0.29 11.8 0.8 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Telomere_reg-2 PF10193.9 KFP01684.1 - 0.18 12.2 2.6 0.72 10.3 2.6 2.0 1 0 0 1 1 1 0 Telomere length regulation protein Trehalase PF01204.18 KFP01684.1 - 0.2 10.5 2.8 2.1 7.1 0.0 2.6 2 0 0 2 2 2 0 Trehalase Tweety PF04906.13 KFP01684.1 - 0.2 10.3 4.5 0.34 9.5 4.5 1.2 1 0 0 1 1 1 0 Tweety SlyX PF04102.12 KFP01684.1 - 3.4 8.4 9.2 4 8.1 4.1 2.9 1 1 1 2 2 2 0 SlyX Baculo_PEP_C PF04513.12 KFP01684.1 - 5.3 7.1 12.4 0.21 11.6 6.0 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GPI2 PF06432.11 KFP01685.1 - 6.3e-58 196.4 7.9 7e-58 196.3 7.9 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase zf-LITAF-like PF10601.9 KFP01685.1 - 1.6 9.0 6.0 1.1 9.6 0.2 2.7 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain Dynamin_M PF01031.20 KFP01686.1 - 2.1e-103 345.5 5.7 2.1e-103 345.5 5.7 2.1 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KFP01686.1 - 1.8e-42 145.2 0.0 6.2e-42 143.5 0.0 2.0 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KFP01686.1 - 7.1e-28 96.6 4.8 7.1e-28 96.6 4.8 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain PH PF00169.29 KFP01686.1 - 1.5e-13 51.2 0.7 3.4e-13 50.0 0.7 1.6 1 0 0 1 1 1 1 PH domain TetR_C_27 PF17935.1 KFP01686.1 - 0.056 13.5 0.4 10 6.2 0.0 3.3 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain PH_11 PF15413.6 KFP01686.1 - 0.11 12.9 1.4 0.62 10.5 1.4 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain Methyltransf_25 PF13649.6 KFP01687.1 - 1.3e-20 73.9 0.0 3.7e-12 46.8 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KFP01687.1 - 9.2e-20 71.0 0.0 1.2e-11 44.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KFP01687.1 - 1.1e-18 67.6 0.1 4.7e-14 52.8 0.0 2.9 2 1 0 2 2 2 2 Methyltransferase domain Spermine_synth PF01564.17 KFP01687.1 - 8.7e-12 44.8 0.0 1.6e-10 40.7 0.0 2.2 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Methyltransf_12 PF08242.12 KFP01687.1 - 1.3e-06 29.1 0.0 0.0065 17.2 0.0 2.9 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KFP01687.1 - 1.7e-05 24.7 0.0 0.047 13.5 0.0 3.2 2 1 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 KFP01687.1 - 4.3e-05 23.1 0.0 0.19 11.3 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase small domain Ubie_methyltran PF01209.18 KFP01687.1 - 0.0014 18.0 0.0 0.013 14.9 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Ham1p_like PF01725.16 KFP01688.1 - 2.1e-36 125.6 0.0 8.6e-18 64.9 0.0 2.0 2 0 0 2 2 2 2 Ham1 family Synaptobrevin PF00957.21 KFP01689.1 - 5.2e-32 109.5 3.0 5.7e-32 109.4 3.0 1.0 1 0 0 1 1 1 1 Synaptobrevin Fzo_mitofusin PF04799.13 KFP01689.1 - 0.013 15.1 0.9 0.013 15.1 0.9 1.4 1 1 0 1 1 1 0 fzo-like conserved region MCU PF04678.13 KFP01689.1 - 0.02 15.0 0.2 0.022 14.8 0.2 1.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter UPF0258 PF06789.12 KFP01689.1 - 0.058 13.5 5.8 0.065 13.4 5.5 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0258) Ferlin_C PF16165.5 KFP01689.1 - 0.065 13.2 0.1 0.07 13.1 0.1 1.1 1 0 0 1 1 1 0 Ferlin C-terminus DHR10 PF18595.1 KFP01689.1 - 0.069 13.2 0.7 0.078 13.0 0.7 1.1 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain GP41 PF00517.17 KFP01689.1 - 4 7.3 10.2 0.15 12.0 0.6 1.9 1 1 1 2 2 2 0 Retroviral envelope protein LRR_8 PF13855.6 KFP01690.1 - 3.1e-50 167.8 49.9 3.3e-12 46.0 5.2 6.9 2 2 5 7 7 7 7 Leucine rich repeat LRR_5 PF13306.6 KFP01690.1 - 2.2e-15 56.7 0.0 7.1e-07 29.2 0.1 2.5 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFP01690.1 - 3.3e-14 52.7 44.7 0.011 16.2 2.5 9.1 3 2 7 11 11 11 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP01690.1 - 6e-07 29.1 15.8 0.009 15.5 0.4 4.3 2 2 2 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 KFP01690.1 - 3.9e-05 23.6 31.4 8 7.5 0.7 10.6 11 1 0 11 11 11 2 Leucine Rich Repeat LRRNT PF01462.18 KFP01690.1 - 0.78 9.5 17.0 0.037 13.7 3.1 3.1 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain Yae1_N PF09811.9 KFP01691.1 - 6e-12 45.1 37.3 2.9e+03 -1.9 37.3 4.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Myotub-related PF06602.14 KFP01693.1 - 2.2e-142 474.2 0.1 3.5e-142 473.5 0.1 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 KFP01693.1 - 0.0034 17.0 0.0 0.0093 15.6 0.0 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFP01693.1 - 0.0044 16.8 0.1 0.02 14.7 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP01693.1 - 0.026 14.5 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Xylo_C PF12529.8 KFP01693.1 - 0.094 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Xylosyltransferase C terminal Nucleoporin_FG2 PF15967.5 KFP01694.1 - 1.2e-247 823.3 60.9 1.4e-247 823.1 60.9 1.0 1 0 0 1 1 1 1 Nucleoporin FG repeated region PSY3 PF16836.5 KFP01694.1 - 0.047 13.2 0.3 0.088 12.3 0.3 1.4 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description Shisa PF13908.6 KFP01695.1 - 3.1e-24 86.3 1.5 5.8e-24 85.4 1.5 1.6 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator Gag_MA PF01140.19 KFP01695.1 - 0.034 13.9 1.0 0.059 13.1 0.2 1.6 1 1 1 2 2 2 0 Matrix protein (MA), p15 Rhabdo_glycop PF00974.18 KFP01695.1 - 0.095 11.1 0.1 0.14 10.6 0.1 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein PhoLip_ATPase_C PF16212.5 KFP01696.1 - 7.3e-74 248.7 15.4 7.3e-74 248.7 15.4 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFP01696.1 - 1.9e-19 69.1 0.8 1.9e-19 69.1 0.8 2.0 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KFP01696.1 - 1.9e-14 53.5 0.0 1.8e-13 50.3 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFP01696.1 - 1.1e-13 51.1 0.0 3.4e-13 49.5 0.0 1.8 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KFP01696.1 - 1.6e-07 31.8 0.4 0.0022 18.3 0.2 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Colicin_im PF03857.13 KFP01696.1 - 0.0047 16.9 0.2 0.0047 16.9 0.2 2.8 2 0 0 2 2 2 1 Colicin immunity protein Hydrolase_3 PF08282.12 KFP01696.1 - 0.013 15.3 0.7 0.041 13.6 0.2 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Fungal_lectin PF07938.12 KFP01696.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal fucose-specific lectin zf-RING_2 PF13639.6 KFP01697.1 - 6.6e-13 48.8 8.2 1e-12 48.2 8.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFP01697.1 - 8.6e-10 38.8 7.2 1.7e-09 37.8 7.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KFP01697.1 - 3.7e-08 33.1 6.9 5.8e-08 32.5 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFP01697.1 - 1.6e-07 31.0 5.2 1.6e-07 31.0 5.2 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KFP01697.1 - 2.6e-07 30.4 7.8 4.2e-07 29.7 7.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFP01697.1 - 1.2e-05 25.3 1.7 2.5e-05 24.3 1.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KFP01697.1 - 7.1e-05 22.6 4.7 0.00011 22.0 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP01697.1 - 9.5e-05 22.3 6.5 0.00015 21.6 6.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP01697.1 - 0.0042 16.9 5.5 0.0075 16.1 5.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFP01697.1 - 0.0046 17.0 1.6 0.0046 17.0 1.6 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 KFP01697.1 - 0.05 13.4 4.6 0.086 12.7 4.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KFP01697.1 - 0.19 11.4 5.5 0.32 10.7 5.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 KFP01697.1 - 0.42 11.0 6.2 0.7 10.3 6.2 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 KFP01697.1 - 2.4 8.3 7.1 5.8 7.1 7.0 1.7 1 1 0 1 1 1 0 RING-variant domain Pkinase PF00069.25 KFP01698.1 - 7.9e-56 189.3 0.1 9.8e-56 189.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP01698.1 - 3.5e-20 72.4 0.0 5.7e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFP01698.1 - 0.0059 16.6 0.1 0.0094 15.9 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFP01698.1 - 0.012 14.9 0.1 0.027 13.8 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KFP01698.1 - 0.12 11.3 0.1 0.63 9.0 0.0 1.8 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase WH2 PF02205.20 KFP01699.1 - 4.1e-07 29.6 0.1 7.4e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 WH2 motif ChaB PF06150.12 KFP01699.1 - 0.053 14.1 0.0 0.15 12.7 0.0 1.7 1 0 0 1 1 1 0 ChaB 7tm_1 PF00001.21 KFP01700.1 - 7.8e-36 123.8 20.5 9.4e-36 123.5 20.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP01700.1 - 1.2e-05 24.8 11.6 1.2e-05 24.8 11.6 2.0 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP01700.1 - 5.4e-05 23.1 19.4 0.0003 20.6 19.4 2.5 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP01700.1 - 0.43 10.2 23.9 0.036 13.7 15.9 2.5 1 1 2 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srx UCH PF00443.29 KFP01701.1 - 1.3e-60 205.1 2.3 1.5e-60 204.9 2.3 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP01701.1 - 6.7e-31 108.1 3.4 9.2e-31 107.6 3.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KFP01701.1 - 0.0061 16.1 10.2 0.013 15.0 7.4 2.5 2 1 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase CEBP_ZZ PF16366.5 KFP01701.1 - 0.78 10.0 6.8 0.51 10.6 1.7 2.4 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Ribosomal_L21e PF01157.18 KFP01702.1 - 2.2e-50 168.7 8.8 2.2e-50 168.7 8.8 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e Nudix_hydro PF18290.1 KFP01702.1 - 0.0033 17.4 0.3 0.005 16.8 0.3 1.3 1 0 0 1 1 1 1 Nudix hydrolase domain CLP_protease PF00574.23 KFP01702.1 - 0.043 13.7 0.1 0.061 13.2 0.1 1.2 1 0 0 1 1 1 0 Clp protease Ras PF00071.22 KFP01703.1 - 3.3e-31 108.1 0.0 4e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP01703.1 - 2.3e-09 37.5 0.0 4.1e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KFP01703.1 - 2.3e-06 27.7 0.0 3.5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KFP01703.1 - 9.6e-05 21.8 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KFP01703.1 - 0.0045 16.9 0.1 1.7 8.5 0.0 2.5 2 1 0 2 2 2 2 RsgA GTPase AlkA_N PF06029.11 KFP01703.1 - 0.021 15.1 0.0 0.063 13.6 0.0 1.8 1 1 0 1 1 1 0 AlkA N-terminal domain AAA_22 PF13401.6 KFP01703.1 - 0.04 14.2 0.0 0.099 12.9 0.0 1.7 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 KFP01703.1 - 0.048 14.1 0.0 0.078 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 KFP01703.1 - 0.097 12.7 0.0 0.18 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain PadR PF03551.14 KFP01703.1 - 0.17 11.9 0.0 0.45 10.5 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family zf-C2H2 PF00096.26 KFP01704.1 - 5.3e-29 99.0 62.9 4.2e-05 23.8 2.0 8.2 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP01704.1 - 3.7e-16 58.7 61.3 0.00013 22.2 1.3 8.5 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP01704.1 - 8e-15 54.3 56.0 0.0025 18.5 1.1 8.0 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFP01704.1 - 0.0034 17.7 29.0 0.61 10.4 8.0 4.7 1 1 4 5 5 5 4 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 KFP01704.1 - 0.0056 16.4 0.9 0.0056 16.4 0.9 7.7 9 0 0 9 9 8 2 C2H2-type zinc-finger domain zf_Hakai PF18408.1 KFP01704.1 - 0.0079 15.9 0.2 0.0079 15.9 0.2 6.1 6 1 0 6 6 6 1 C2H2 Hakai zinc finger domain FOXP-CC PF16159.5 KFP01704.1 - 0.011 16.4 35.5 0.076 13.6 0.0 7.0 3 2 3 7 7 7 0 FOXP coiled-coil domain zf-Di19 PF05605.12 KFP01704.1 - 0.015 15.6 26.7 0.23 11.8 5.8 4.8 2 2 4 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_ZHX PF18387.1 KFP01704.1 - 0.16 11.6 0.2 0.16 11.6 0.2 4.2 1 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Ogr_Delta PF04606.12 KFP01704.1 - 0.35 10.9 0.1 0.35 10.9 0.1 6.0 5 1 2 7 7 7 0 Ogr/Delta-like zinc finger zf-C2H2_jaz PF12171.8 KFP01704.1 - 0.39 11.1 38.8 0.39 11.1 0.2 6.3 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP01704.1 - 0.78 10.2 28.1 3.5 8.2 0.1 6.7 7 0 0 7 7 6 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFP01704.1 - 1.2 8.9 0.0 1.2 8.9 0.0 4.1 4 0 0 4 4 4 0 zinc-finger C2H2-type IF3_N PF05198.16 KFP01705.1 - 3.9e-17 62.3 0.1 4.3e-16 58.9 0.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 KFP01705.1 - 1.2e-08 34.8 1.1 3.2e-08 33.4 0.7 2.1 1 1 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain HTH_33 PF13592.6 KFP01705.1 - 0.077 12.6 0.1 0.2 11.3 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn helix DUF4974 PF16344.5 KFP01705.1 - 0.11 12.5 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) PDZ PF00595.24 KFP01706.1 - 6e-65 215.6 1.5 8.8e-16 58.0 0.0 4.2 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 KFP01706.1 - 1.6e-30 104.7 1.2 1.7e-07 31.0 0.0 4.4 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 KFP01706.1 - 1.3e-17 63.9 0.2 3.5e-05 24.0 0.0 4.3 4 0 0 4 4 4 4 PDZ domain zf-C3HC4_2 PF13923.6 KFP01706.1 - 2.7e-08 33.5 8.4 2.7e-08 33.5 8.4 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP01706.1 - 4.3e-08 32.9 6.7 4.3e-08 32.9 6.7 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP01706.1 - 6.2e-07 29.6 6.1 6.2e-07 29.6 6.1 3.5 5 0 0 5 5 4 1 Ring finger domain zf-RING_UBOX PF13445.6 KFP01706.1 - 8.2e-07 28.9 7.9 8.2e-07 28.9 7.9 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFP01706.1 - 2e-06 27.5 3.1 2e-06 27.5 3.1 3.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP01706.1 - 8.4e-06 25.6 5.4 8.4e-06 25.6 5.4 2.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFP01706.1 - 9.2e-05 22.5 7.6 9.2e-05 22.5 7.6 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KFP01706.1 - 0.0022 18.2 4.3 0.0022 18.2 4.3 2.4 2 1 0 2 2 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFP01706.1 - 0.13 12.1 9.7 0.061 13.2 5.0 2.8 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KFP01706.1 - 0.15 11.9 2.2 0.39 10.6 2.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit eIF3g PF12353.8 KFP01706.1 - 0.56 10.6 2.9 6.5 7.2 0.4 2.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G DZR PF12773.7 KFP01706.1 - 0.61 10.2 10.2 1.3 9.1 5.9 3.1 2 1 0 2 2 2 0 Double zinc ribbon zf-RING_11 PF17123.5 KFP01706.1 - 1.4 8.7 7.8 1 9.1 4.4 2.7 2 1 0 2 2 2 0 RING-like zinc finger WDCP PF15390.6 KFP01707.1 - 0.5 8.7 5.1 0.45 8.9 5.1 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family LCD1 PF09798.9 KFP01707.1 - 3 6.3 5.9 3.4 6.1 5.9 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Pan3_PK PF18101.1 KFP01709.1 - 1.4e-62 209.7 0.0 2.3e-62 209.0 0.0 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KFP01709.1 - 0.0015 18.0 0.0 0.0046 16.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP01710.1 - 7.7e-105 349.8 0.0 1.2e-104 349.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP01710.1 - 1.6e-43 149.0 0.0 2.7e-29 102.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.6 KFP01710.1 - 9.5e-27 93.4 0.5 4.4e-14 52.9 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFP01710.1 - 2.5e-26 91.6 0.0 1.6e-16 60.1 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP01710.1 - 2.9e-22 78.8 0.0 2.5e-11 43.7 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP01710.1 - 4.8e-19 68.3 0.0 4.8e-08 33.1 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain VEGFR-2_TMD PF17988.1 KFP01710.1 - 9.9e-18 63.3 0.4 1.8e-17 62.4 0.4 1.5 1 0 0 1 1 1 1 VEGFR-2 Transmembrane domain V-set PF07686.17 KFP01710.1 - 2.5e-10 40.5 1.1 0.00018 21.6 0.1 4.1 2 2 1 3 3 3 2 Immunoglobulin V-set domain Ig_4 PF16680.5 KFP01710.1 - 6.7e-06 26.3 0.0 0.014 15.7 0.0 3.0 2 0 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFP01710.1 - 0.00051 20.0 0.1 0.6 10.2 0.0 2.9 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFP01710.1 - 0.0024 17.4 0.0 0.19 11.3 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain Haspin_kinase PF12330.8 KFP01710.1 - 0.0068 15.4 0.0 0.015 14.3 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Herpes_gE PF02480.16 KFP01710.1 - 0.0082 14.9 0.0 0.097 11.4 0.0 2.2 1 1 0 2 2 2 1 Alphaherpesvirus glycoprotein E C2-set_2 PF08205.12 KFP01710.1 - 0.31 11.1 1.6 1 9.5 0.0 2.5 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain UMP1 PF05348.11 KFP01711.1 - 4e-24 85.1 0.0 4.3e-24 85.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 MFS_1 PF07690.16 KFP01712.1 - 1.6e-14 53.6 27.9 1.6e-14 53.6 27.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF5360 PF17314.2 KFP01712.1 - 0.2 11.7 0.1 0.2 11.7 0.1 3.8 3 1 1 4 4 4 0 Family of unknown function (DUF5360) RTBV_P46 PF06216.11 KFP01713.1 - 2.7 6.8 7.3 0.56 9.0 2.5 2.0 1 1 0 2 2 2 0 Rice tungro bacilliform virus P46 protein Spore_YhcN_YlaJ PF09580.10 KFP01713.1 - 4.7 7.3 9.1 1.4 9.0 2.9 2.8 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) AA_permease_2 PF13520.6 KFP01715.1 - 1.1e-54 185.9 23.4 1.1e-54 185.9 23.4 2.3 2 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 KFP01715.1 - 1.5e-42 145.8 22.8 1.5e-42 145.8 22.8 2.5 2 1 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 KFP01715.1 - 3.5e-25 87.8 9.5 3.5e-25 87.8 9.5 4.0 5 0 0 5 5 5 1 C-terminus of AA_permease OST3_OST6 PF04756.13 KFP01715.1 - 0.0095 15.3 1.7 0.0095 15.3 1.7 3.3 4 1 0 4 4 4 1 OST3 / OST6 family, transporter family DUF3278 PF11683.8 KFP01715.1 - 0.31 11.1 9.9 0.16 12.1 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) Rad60-SLD_2 PF13881.6 KFP01716.1 - 3.7e-33 113.9 0.0 4.2e-33 113.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KFP01716.1 - 8.9e-05 22.2 0.0 0.00019 21.1 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KFP01716.1 - 0.045 14.3 0.0 0.06 13.9 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Met_gamma_lyase PF06838.11 KFP01716.1 - 0.077 11.5 0.0 0.098 11.2 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase AAA PF00004.29 KFP01717.1 - 7.1e-40 136.5 0.0 1.6e-39 135.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFP01717.1 - 6.7e-14 51.4 2.9 1.5e-13 50.3 0.4 2.9 2 1 0 2 2 2 1 AAA+ lid domain Vps4_C PF09336.10 KFP01717.1 - 1.7e-09 37.5 0.1 1.1e-08 35.0 0.0 2.4 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 KFP01717.1 - 1.5e-05 24.8 0.0 2.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KFP01717.1 - 2.3e-05 24.6 0.0 4.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KFP01717.1 - 3e-05 24.2 0.0 5.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KFP01717.1 - 3.7e-05 24.2 0.1 0.023 15.1 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KFP01717.1 - 0.0002 21.3 0.2 0.0016 18.4 0.2 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KFP01717.1 - 0.0003 20.1 0.0 0.0005 19.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 KFP01717.1 - 0.00075 18.9 0.2 0.0016 17.8 0.2 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KFP01717.1 - 0.0014 18.6 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KFP01717.1 - 0.0024 18.2 0.4 0.075 13.3 0.2 2.9 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.6 KFP01717.1 - 0.0025 17.9 0.0 0.0065 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFP01717.1 - 0.0034 17.1 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 KFP01717.1 - 0.0044 16.8 0.1 0.33 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFP01717.1 - 0.0059 17.1 0.5 0.028 15.0 0.5 2.1 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KFP01717.1 - 0.0076 15.8 0.3 0.019 14.5 0.2 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region ATPase PF06745.13 KFP01717.1 - 0.03 13.6 0.2 2.5 7.4 0.1 2.3 1 1 1 2 2 2 0 KaiC NACHT PF05729.12 KFP01717.1 - 0.044 13.7 0.1 0.12 12.3 0.1 1.7 1 1 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 KFP01717.1 - 0.052 13.8 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KFP01717.1 - 0.056 12.9 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 KFP01717.1 - 0.069 13.5 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 KFP01717.1 - 0.069 13.6 0.0 0.22 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain TPR_8 PF13181.6 KFP01717.1 - 0.11 12.7 1.9 5.9 7.4 0.2 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat Guanylate_kin PF00625.21 KFP01717.1 - 0.12 12.0 0.0 0.48 10.1 0.0 2.0 2 0 0 2 2 2 0 Guanylate kinase AAA_30 PF13604.6 KFP01717.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KFP01717.1 - 0.16 11.5 0.3 0.63 9.6 0.3 2.0 1 1 1 2 2 2 0 AAA domain HMG_box PF00505.19 KFP01718.1 - 3.7e-42 142.6 12.6 2e-27 95.4 0.5 2.8 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP01718.1 - 7.7e-41 138.5 20.2 9.9e-27 93.4 7.4 2.6 3 0 0 3 3 3 2 HMG-box domain HMG_box_5 PF14887.6 KFP01718.1 - 0.086 12.8 16.4 0.48 10.4 3.9 2.5 2 1 0 2 2 2 0 HMG (high mobility group) box 5 Astro_capsid_p PF12226.8 KFP01718.1 - 1.5 7.9 16.2 2 7.5 16.2 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CENP-I PF07778.11 KFP01718.1 - 2.2 6.9 7.6 3.2 6.3 7.6 1.2 1 0 0 1 1 1 0 Mis6 NOA36 PF06524.12 KFP01718.1 - 3.3 6.9 27.0 0.065 12.5 20.4 1.5 2 0 0 2 2 2 0 NOA36 protein DUF4650 PF15509.6 KFP01719.1 - 3.4e-152 508.4 22.1 3.4e-152 508.4 22.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4650) Peptidase_C98 PF15499.6 KFP01719.1 - 1.4e-121 405.1 8.3 1.4e-121 405.1 8.3 2.0 2 0 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase MAPEG PF01124.18 KFP01720.1 - 4.4e-08 33.1 0.6 5.3e-08 32.8 0.6 1.2 1 0 0 1 1 1 1 MAPEG family Fringe PF02434.16 KFP01721.1 - 7.9e-66 222.1 0.0 4.4e-58 196.7 0.0 2.6 2 1 1 3 3 3 2 Fringe-like Galactosyl_T PF01762.21 KFP01721.1 - 2.9e-08 33.8 0.0 0.13 12.1 0.0 3.3 2 1 1 3 3 3 3 Galactosyltransferase DUF604 PF04646.12 KFP01721.1 - 0.00014 21.4 0.1 0.0022 17.5 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF604 Glycos_transf_2 PF00535.26 KFP01721.1 - 0.0033 17.3 0.0 0.0074 16.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 RVT_1 PF00078.27 KFP01722.1 - 4.4e-22 78.7 0.0 6.8e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFP01722.1 - 5.7e-05 23.1 0.0 9.8e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-C3HC4_2 PF13923.6 KFP01723.1 - 6.6e-12 45.1 9.5 1.6e-11 43.8 9.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RAWUL PF16207.5 KFP01723.1 - 6.7e-12 45.9 0.7 1.6e-11 44.7 0.3 1.9 2 0 0 2 2 2 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4 PF00097.25 KFP01723.1 - 3.1e-09 36.6 10.3 3.1e-09 36.6 10.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP01723.1 - 1.1e-07 32.0 9.0 1.1e-07 32.0 9.0 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFP01723.1 - 1.6e-05 24.6 9.8 1.6e-05 24.6 9.8 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP01723.1 - 3.2e-05 23.8 11.0 3.2e-05 23.8 11.0 2.6 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFP01723.1 - 0.0001 22.2 6.2 0.0001 22.2 6.2 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 KFP01723.1 - 0.00013 22.1 6.2 0.00013 22.1 6.2 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KFP01723.1 - 0.0015 18.6 9.6 0.0015 18.6 9.6 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KFP01723.1 - 0.0066 16.2 9.1 0.01 15.6 6.0 2.5 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain GAGA PF09237.11 KFP01723.1 - 0.028 14.2 0.1 0.088 12.6 0.1 1.8 1 0 0 1 1 1 0 GAGA factor zf-Nse PF11789.8 KFP01723.1 - 0.035 13.9 3.9 0.061 13.1 3.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 KFP01723.1 - 0.036 14.2 6.1 0.036 14.2 6.1 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 KFP01723.1 - 0.26 11.2 17.2 0.13 12.2 12.1 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 DZR PF12773.7 KFP01723.1 - 1 9.5 9.7 1.2 9.2 5.7 2.4 2 0 0 2 2 2 0 Double zinc ribbon DUF1272 PF06906.11 KFP01723.1 - 1.5 8.9 9.1 1.2 9.3 6.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DUF3337 PF11816.8 KFP01723.1 - 1.8 8.4 5.1 37 4.1 5.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3337) MRP-S33 PF08293.11 KFP01724.1 - 7.3e-26 90.2 2.6 9.3e-26 89.9 2.6 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Pkinase_Tyr PF07714.17 KFP01725.1 - 1.5e-63 214.5 0.0 2.2e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP01725.1 - 1e-58 198.8 0.0 1.4e-58 198.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RBD PF02196.15 KFP01725.1 - 1.5e-26 92.2 0.0 3.6e-26 91.0 0.0 1.7 1 0 0 1 1 1 1 Raf-like Ras-binding domain C1_1 PF00130.22 KFP01725.1 - 3.3e-12 46.1 7.1 6.4e-12 45.2 7.1 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 KFP01725.1 - 1.1e-08 34.7 0.0 1.7e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like zf-RING-like PF08746.11 KFP01725.1 - 7.7e-05 22.9 2.7 0.00021 21.6 2.7 1.7 1 0 0 1 1 1 1 RING-like domain C1_2 PF03107.16 KFP01725.1 - 0.0032 17.8 3.6 0.007 16.7 3.6 1.6 1 0 0 1 1 1 1 C1 domain Pkinase_fungal PF17667.1 KFP01725.1 - 0.0043 15.9 0.0 0.0071 15.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP01725.1 - 0.052 13.5 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KFP01725.1 - 0.11 11.9 0.1 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 KFP01726.1 - 1.7e-18 66.9 0.0 8.4e-15 55.0 0.0 2.9 3 0 0 3 3 3 2 ABC1 family APH PF01636.23 KFP01726.1 - 0.018 15.0 0.0 0.018 15.0 0.0 2.5 3 1 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 KFP01726.1 - 0.067 12.5 0.6 2.6 7.3 0.0 2.4 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DENN PF02141.21 KFP01727.1 - 3.8e-57 193.3 1.1 7.9e-57 192.2 1.1 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KFP01727.1 - 4.7e-16 59.3 0.2 1e-15 58.2 0.2 1.6 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KFP01727.1 - 8.8e-12 44.8 0.7 2.6e-11 43.3 0.7 1.9 1 0 0 1 1 1 1 dDENN domain SPA PF08616.10 KFP01727.1 - 0.19 11.7 0.1 0.4 10.6 0.1 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis Indigoidine_A PF04227.12 KFP01728.1 - 2.6e-130 434.0 2.8 3.3e-130 433.7 2.2 1.4 2 0 0 2 2 2 1 Indigoidine synthase A like protein PfkB PF00294.24 KFP01728.1 - 3.7e-18 65.9 0.0 7.5e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase MKRN1_C PF15815.5 KFP01729.1 - 2.6e-30 104.6 6.4 8.9e-30 102.9 6.4 1.9 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase makorin-1, C-terminal zf-CCCH_4 PF18044.1 KFP01729.1 - 4.6e-26 90.1 38.6 2e-07 30.6 0.4 4.6 4 0 0 4 4 4 4 CCCH-type zinc finger Torus PF16131.5 KFP01729.1 - 7.3e-16 58.8 16.4 3.7e-05 24.4 1.1 4.4 3 1 1 4 4 4 4 Torus domain zf-CCCH PF00642.24 KFP01729.1 - 3.7e-14 52.2 33.9 1.5e-05 24.7 0.1 4.4 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFP01729.1 - 5.8e-13 48.4 39.6 2.4e-05 24.2 2.4 5.0 4 1 0 4 4 4 3 Zinc finger domain zf-C3HC4 PF00097.25 KFP01729.1 - 7e-07 29.0 7.1 7e-07 29.0 7.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP01729.1 - 9.7e-06 25.5 3.0 2.7e-05 24.1 3.0 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP01729.1 - 3.8e-05 23.6 6.1 3.8e-05 23.6 6.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFP01729.1 - 6.4e-05 23.2 6.2 6.4e-05 23.2 6.2 2.8 2 1 0 2 2 1 1 Ring finger domain zf-CCCH_3 PF15663.5 KFP01729.1 - 0.00014 22.0 4.3 0.00014 22.0 4.3 3.2 3 1 0 3 3 3 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KFP01729.1 - 0.00048 20.5 29.5 0.98 10.0 1.3 4.9 4 1 0 4 4 4 4 RNA-binding, Nab2-type zinc finger zf-ANAPC11 PF12861.7 KFP01729.1 - 0.00056 19.9 2.6 0.00056 19.9 2.6 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KFP01729.1 - 0.001 19.3 5.0 0.001 19.3 5.0 3.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KFP01729.1 - 0.0038 17.4 4.0 0.0038 17.4 4.0 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KFP01729.1 - 0.015 15.0 2.4 0.058 13.1 2.4 2.1 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFP01729.1 - 0.75 9.7 15.9 0.55 10.1 10.1 3.6 3 1 0 3 3 2 0 Zinc finger, C3HC4 type (RING finger) Ras PF00071.22 KFP01730.1 - 3.8e-56 189.2 0.6 4.4e-56 189.0 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP01730.1 - 6e-36 123.3 0.4 9.1e-36 122.7 0.4 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP01730.1 - 2.6e-15 56.3 0.2 3.3e-15 56.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP01730.1 - 9.2e-06 25.3 0.6 4.5e-05 23.1 0.6 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFP01730.1 - 4.4e-05 23.5 0.1 6.8e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFP01730.1 - 0.00012 21.5 0.2 0.00018 21.0 0.2 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFP01730.1 - 0.00027 20.4 0.1 0.00066 19.1 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KFP01730.1 - 0.0005 19.6 0.4 0.056 13.0 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B TniB PF05621.11 KFP01730.1 - 0.0022 17.4 0.1 0.0037 16.7 0.1 1.3 1 0 0 1 1 1 1 Bacterial TniB protein PduV-EutP PF10662.9 KFP01730.1 - 0.0043 16.8 0.5 0.091 12.5 0.1 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 KFP01730.1 - 0.034 13.9 0.0 0.049 13.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 KFP01730.1 - 0.079 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Septin MFS_1 PF07690.16 KFP01731.1 - 7.4e-41 140.2 26.2 3.6e-37 128.1 13.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP01731.1 - 8.4e-05 21.6 31.3 0.0023 16.8 9.6 3.0 2 2 0 2 2 2 2 Sugar (and other) transporter Gly-zipper_YMGG PF13441.6 KFP01731.1 - 3.3 7.5 0.0 3.3 7.5 0.0 3.8 4 1 0 4 4 4 0 YMGG-like Gly-zipper JHD PF17811.1 KFP01732.1 - 3.5e-43 146.4 1.3 4.8e-43 145.9 0.1 2.0 2 0 0 2 2 2 1 Jumonji helical domain JmjC PF02373.22 KFP01732.1 - 3e-11 43.8 2.1 5.6e-10 39.7 2.1 2.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KFP01732.1 - 7.3e-09 35.7 6.4 3e-08 33.7 0.3 2.8 2 1 0 2 2 2 1 Cupin-like domain AA_permease_2 PF13520.6 KFP01733.1 - 3.8e-51 174.3 36.4 4.4e-51 174.1 36.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFP01733.1 - 5.4e-25 87.9 26.5 5.4e-25 87.9 26.5 1.9 2 0 0 2 2 2 2 Amino acid permease PARP PF00644.20 KFP01734.1 - 4e-40 137.5 0.0 1.4e-39 135.7 0.0 1.7 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain HJURP_C PF12347.8 KFP01734.1 - 0.056 13.5 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat Aldo_ket_red PF00248.21 KFP01735.1 - 1e-44 152.9 0.0 1.4e-44 152.5 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Bromodomain PF00439.25 KFP01736.1 - 4.7e-22 77.9 0.1 1.1e-21 76.6 0.1 1.7 1 0 0 1 1 1 1 Bromodomain zf-B_box PF00643.24 KFP01736.1 - 3.2e-11 43.2 24.0 1.9e-09 37.5 7.7 4.7 5 0 0 5 5 5 2 B-box zinc finger PHD PF00628.29 KFP01736.1 - 1.1e-07 31.6 11.1 1.1e-07 31.6 11.1 4.5 4 1 0 4 4 4 1 PHD-finger zf-Sec23_Sec24 PF04810.15 KFP01736.1 - 7.7 6.7 8.6 3 8.0 2.4 3.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger MFS_1 PF07690.16 KFP01737.1 - 2.6e-30 105.5 42.7 1.8e-22 79.7 20.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP01737.1 - 9.1e-22 77.5 33.5 9.2e-19 67.6 10.0 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter V_ATPase_I PF01496.19 KFP01738.1 - 0 1063.0 7.1 0 1062.8 7.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family TMEM213 PF15192.6 KFP01739.1 - 6.8e-32 109.3 1.5 7.1e-32 109.2 1.5 1.0 1 0 0 1 1 1 1 TMEM213 family DUF3827 PF12877.7 KFP01740.1 - 4.8e-300 996.9 1.9 6.1e-300 996.5 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) SKG6 PF08693.10 KFP01740.1 - 0.0011 18.4 1.9 0.0023 17.3 1.9 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Pkinase PF00069.25 KFP01741.1 - 5.9e-52 176.6 0.0 1.4e-51 175.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP01741.1 - 1.9e-24 86.3 0.0 3.3e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFP01741.1 - 3.3e-07 29.9 0.0 2.7e-05 23.7 0.0 2.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFP01741.1 - 0.0033 16.3 0.0 0.0054 15.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP01741.1 - 0.0078 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KFP01741.1 - 0.0082 15.2 0.1 0.012 14.6 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase FTA2 PF13095.6 KFP01741.1 - 0.073 12.7 0.1 9.7 5.7 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RVT_1 PF00078.27 KFP01742.1 - 0.0036 16.8 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) p450 PF00067.22 KFP01743.1 - 1.5e-90 304.2 0.7 7.1e-72 242.6 0.2 2.0 2 0 0 2 2 2 2 Cytochrome P450 PARP PF00644.20 KFP01744.1 - 2.4e-42 144.7 0.8 8.4e-42 143.0 0.8 1.7 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain I-set PF07679.16 KFP01745.1 - 1e-58 195.4 4.5 4.2e-13 49.2 0.0 5.5 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP01745.1 - 8.7e-38 128.8 0.1 4.8e-07 30.3 0.0 5.9 6 0 0 6 6 5 5 Immunoglobulin domain fn3 PF00041.21 KFP01745.1 - 5.6e-26 90.7 0.0 5.1e-14 52.4 0.0 3.5 3 1 0 3 3 3 2 Fibronectin type III domain Ig_2 PF13895.6 KFP01745.1 - 1.2e-24 86.4 0.0 0.00018 21.7 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin domain THB PF18362.1 KFP01745.1 - 1.4e-21 75.8 0.4 6.8e-21 73.6 0.0 2.1 2 0 0 2 2 2 1 Tri-helix bundle domain ig PF00047.25 KFP01745.1 - 1.2e-20 73.5 0.1 0.00012 22.1 0.0 5.6 5 0 0 5 5 5 4 Immunoglobulin domain V-set PF07686.17 KFP01745.1 - 1.3e-09 38.2 0.9 4.9 7.4 0.1 6.3 5 1 0 5 5 5 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP01745.1 - 0.00058 19.9 0.0 2.7 8.1 0.0 4.4 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain PKD_3 PF16820.5 KFP01745.1 - 0.0011 18.7 1.2 4.6 7.1 0.1 4.4 4 0 0 4 4 4 1 PKD-like domain C1-set PF07654.15 KFP01745.1 - 0.0012 19.2 1.3 4 7.9 0.0 3.8 4 0 0 4 4 4 1 Immunoglobulin C1-set domain Ig_5 PF16681.5 KFP01745.1 - 0.0019 18.6 3.4 3 8.3 0.1 4.7 5 0 0 5 5 5 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Top6b_C PF18000.1 KFP01745.1 - 0.018 15.2 0.0 0.082 13.1 0.0 2.2 1 1 0 1 1 1 0 Type 2 DNA topoisomerase 6 subunit B C-terminal domain SusE PF14292.6 KFP01745.1 - 0.024 14.9 0.0 0.064 13.5 0.0 1.7 1 0 0 1 1 1 0 SusE outer membrane protein Ig_4 PF16680.5 KFP01745.1 - 0.071 13.4 4.9 2.2 8.6 0.0 4.2 4 1 1 5 5 5 0 T-cell surface glycoprotein CD3 delta chain LIFR_D2 PF17971.1 KFP01745.1 - 0.096 12.9 0.1 2.1 8.5 0.0 2.8 3 0 0 3 3 3 0 Leukemia inhibitory factor receptor D2 domain DUF4251 PF14059.6 KFP01745.1 - 0.11 12.5 0.3 1.6 8.7 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4251) Izumo-Ig PF16706.5 KFP01745.1 - 0.19 11.8 0.4 44 4.2 0.0 3.1 4 0 0 4 4 2 0 Izumo-like Immunoglobulin domain Cullin PF00888.22 KFP01747.1 - 6.9e-14 51.4 0.0 7.5e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Cullin family Herpes_pp85 PF04637.12 KFP01747.1 - 0.0044 15.5 0.0 0.0066 14.9 0.0 1.3 1 0 0 1 1 1 1 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DNA_repr_REX1B PF14966.6 KFP01747.1 - 0.024 15.3 0.1 0.052 14.2 0.1 1.6 1 0 0 1 1 1 0 DNA repair REX1-B DUF4853 PF16145.5 KFP01747.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4853) PCI PF01399.27 KFP01748.1 - 3e-19 69.4 0.1 3e-19 69.4 0.1 4.4 5 0 0 5 5 5 1 PCI domain SPA PF08616.10 KFP01749.1 - 8.3e-11 41.8 0.0 1.6e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KFP01749.1 - 9.4e-11 41.0 0.0 5.9e-07 28.5 0.0 2.1 1 1 1 2 2 2 2 Transport protein Avl9 DUF2347 PF09804.9 KFP01749.1 - 1.8e-08 34.4 0.1 5e-08 32.9 0.1 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Toxin-deaminase PF14424.6 KFP01749.1 - 0.0081 16.3 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 The BURPS668_1122 family of deaminases Mtc PF03820.17 KFP01750.1 - 1.4e-57 195.1 0.1 1.7e-57 194.9 0.1 1.1 1 0 0 1 1 1 1 Tricarboxylate carrier SSF PF00474.17 KFP01750.1 - 0.032 13.1 2.5 0.39 9.5 0.3 2.1 2 0 0 2 2 2 0 Sodium:solute symporter family AhpC-TSA PF00578.21 KFP01751.1 - 1.5e-36 125.0 0.0 2.1e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFP01751.1 - 1.3e-16 60.7 0.0 1.6e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KFP01751.1 - 4.6e-14 52.0 0.0 7.5e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 KFP01751.1 - 0.004 17.1 0.5 0.0075 16.2 0.1 1.5 2 0 0 2 2 2 1 SCO1/SenC Thioredoxin_8 PF13905.6 KFP01751.1 - 0.061 13.6 0.0 0.11 12.8 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like Endothelin PF00322.17 KFP01751.1 - 0.8 9.4 3.2 1.7 8.4 3.2 1.6 1 1 0 1 1 1 0 Endothelin family Pkinase PF00069.25 KFP01752.1 - 7.3e-66 222.2 0.0 1.1e-65 221.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP01752.1 - 7e-34 117.3 0.0 1.1e-33 116.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 KFP01752.1 - 2.6e-23 82.5 0.1 7.4e-23 81.1 0.1 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain Kinase-like PF14531.6 KFP01752.1 - 6.2e-05 22.5 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP01752.1 - 0.0013 17.6 0.0 0.0039 16.0 0.0 1.6 1 1 0 1 1 1 1 Fungal protein kinase Arteri_nucleo PF01481.16 KFP01752.1 - 0.18 12.1 0.8 5.5 7.3 0.0 3.2 4 0 0 4 4 4 0 Arterivirus nucleocapsid protein RGS PF00615.19 KFP01754.1 - 7.4e-33 113.3 5.8 7.4e-33 113.3 5.8 1.5 2 0 0 2 2 2 1 Regulator of G protein signaling domain RGS-like PF09128.11 KFP01754.1 - 0.00028 20.6 0.2 0.00049 19.9 0.1 1.4 1 1 0 1 1 1 1 Regulator of G protein signalling-like domain RRM_1 PF00076.22 KFP01755.1 - 4.3e-60 199.5 0.0 1.2e-21 76.3 0.0 4.2 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP01755.1 - 4.6e-09 36.0 0.0 5.1e-05 23.0 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 KFP01755.1 - 7e-08 32.5 0.2 0.26 11.4 0.0 4.4 3 1 0 3 3 3 3 RNA recognition motif Nup35_RRM_2 PF14605.6 KFP01755.1 - 8.1e-05 22.5 0.3 0.15 12.1 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Calcipressin PF04847.12 KFP01755.1 - 0.00091 19.0 0.0 0.39 10.4 0.0 2.6 3 0 0 3 3 3 2 Calcipressin Nup35_RRM PF05172.13 KFP01755.1 - 0.00093 19.1 0.2 0.36 10.8 0.2 3.5 1 1 1 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KFP01755.1 - 0.0098 15.9 0.0 12 6.0 0.0 3.2 3 0 0 3 3 3 1 RNA binding motif DbpA PF03880.15 KFP01755.1 - 0.15 12.1 0.0 4 7.5 0.0 2.8 3 0 0 3 3 3 0 DbpA RNA binding domain BAG PF02179.16 KFP01756.1 - 2.2e-18 66.5 4.1 3.8e-18 65.7 4.1 1.4 1 0 0 1 1 1 1 BAG domain Syja_N PF02383.18 KFP01757.1 - 1e-98 330.6 0.8 2e-98 329.7 0.8 1.5 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 KFP01757.1 - 7.1e-21 74.1 0.0 3.5e-20 71.8 0.0 2.2 2 0 0 2 2 2 1 Inositol phosphatase HSM3_C PF18794.1 KFP01757.1 - 0.025 14.2 0.3 0.81 9.2 0.1 2.5 2 0 0 2 2 2 0 DNA mismatch repair protein HSM3, C terminal domain DHO_dh PF01180.21 KFP01757.1 - 0.11 11.7 0.1 0.28 10.3 0.1 1.6 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase MCM_bind PF09739.9 KFP01758.1 - 9.7e-239 793.7 0.0 1.1e-238 793.5 0.0 1.0 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor WWE PF02825.20 KFP01759.1 - 2.5e-11 44.0 2.8 5e-05 23.8 0.2 2.4 1 1 1 2 2 2 2 WWE domain zf-CCHH PF10283.9 KFP01760.1 - 4.4e-25 87.3 16.4 4.3e-13 49.0 2.6 2.4 2 0 0 2 2 2 2 PBZ domain HUN PF08729.10 KFP01760.1 - 0.0039 17.2 10.2 0.011 15.7 10.2 1.8 1 0 0 1 1 1 1 HPC2 and ubinuclein domain SsgA PF04686.12 KFP01760.1 - 0.04 13.9 0.0 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 Streptomyces sporulation and cell division protein, SsgA F-box-like PF12937.7 KFP01761.1 - 8.7e-11 41.5 0.2 1.9e-10 40.5 0.0 1.7 1 1 1 2 2 2 1 F-box-like F-box PF00646.33 KFP01761.1 - 1.7e-05 24.5 0.0 1.7e-05 24.5 0.0 2.2 3 0 0 3 3 3 1 F-box domain PH PF00169.29 KFP01762.1 - 2.6e-34 117.9 0.0 2.2e-16 60.3 0.0 2.4 2 0 0 2 2 2 2 PH domain DEP PF00610.21 KFP01762.1 - 1.7e-12 47.2 0.0 3.1e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_9 PF15410.6 KFP01762.1 - 3.2e-10 40.4 0.0 5.9e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain PH_6 PF15406.6 KFP01762.1 - 2.2e-09 37.6 0.0 3.8e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH_13 PF16652.5 KFP01762.1 - 7.2e-06 25.9 0.1 0.15 11.9 0.0 2.3 2 0 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 KFP01762.1 - 0.00058 20.2 4.3 1.5 9.2 0.2 4.1 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 KFP01762.1 - 0.00073 19.8 0.1 0.2 12.0 0.0 3.5 2 2 1 3 3 3 1 Pleckstrin homology domain PH_2 PF08458.10 KFP01762.1 - 0.079 13.3 0.0 3 8.3 0.0 2.2 2 0 0 2 2 2 0 Plant pleckstrin homology-like region PH_16 PF17838.1 KFP01762.1 - 0.1 12.4 0.2 5.7 6.8 0.1 2.4 2 0 0 2 2 2 0 PH domain CNRIP1 PF15043.6 KFP01763.1 - 5.8e-66 220.9 0.0 6.4e-66 220.7 0.0 1.0 1 0 0 1 1 1 1 CB1 cannabinoid receptor-interacting protein 1 EF-hand_1 PF00036.32 KFP01764.1 - 8.3e-28 93.8 14.2 1.2e-06 27.6 0.4 4.9 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 KFP01764.1 - 5.7e-26 90.8 5.4 2.1e-14 53.7 0.5 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP01764.1 - 3.7e-22 76.3 6.6 1.3e-05 24.7 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFP01764.1 - 4.3e-22 76.6 9.5 2.5e-05 23.6 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KFP01764.1 - 5.8e-19 67.7 7.4 0.0015 18.4 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFP01764.1 - 5.5e-09 36.3 0.2 0.0015 18.9 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFP01764.1 - 1.8e-07 31.0 4.6 0.0075 16.2 0.2 3.7 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFP01764.1 - 0.00065 20.0 0.2 0.079 13.3 0.0 2.7 2 1 1 3 3 3 1 EF-hand domain Caleosin PF05042.13 KFP01764.1 - 0.029 14.3 3.1 9.7 6.1 0.1 3.4 2 2 2 4 4 4 0 Caleosin related protein Dockerin_1 PF00404.18 KFP01764.1 - 9 6.6 9.8 15 5.9 2.9 3.3 2 2 1 3 3 3 0 Dockerin type I domain KH_8 PF17903.1 KFP01765.1 - 7.4e-05 22.8 0.1 0.00013 22.0 0.1 1.3 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KFP01765.1 - 0.00023 20.9 0.8 0.00056 19.7 0.8 1.6 1 0 0 1 1 1 1 KH domain WD40 PF00400.32 KFP01766.1 - 6.2e-13 49.0 3.5 0.00018 22.2 0.0 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP01766.1 - 0.001 19.3 0.0 0.97 9.8 0.0 2.9 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Itfg2 PF15907.5 KFP01766.1 - 0.0073 15.4 0.3 0.11 11.5 0.0 2.4 1 1 1 2 2 2 1 Integrin-alpha FG-GAP repeat-containing protein 2 BBS2_Mid PF14783.6 KFP01766.1 - 0.012 15.6 0.1 0.27 11.3 0.0 2.6 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.11 KFP01766.1 - 0.022 14.6 0.0 7.6 6.4 0.0 3.0 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A PHTB1_N PF14727.6 KFP01766.1 - 0.12 11.7 0.0 13 5.0 0.0 2.7 2 1 1 3 3 3 0 PTHB1 N-terminus Sas10_Utp3 PF04000.15 KFP01767.1 - 9.6e-17 61.4 0.5 1.5e-16 60.8 0.5 1.3 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DUF932 PF06067.11 KFP01767.1 - 0.011 15.5 1.0 0.011 15.5 0.3 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF932) ING PF12998.7 KFP01767.1 - 0.095 13.3 1.4 2.1 9.0 1.4 2.1 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding ETAA1 PF15350.6 KFP01768.1 - 2.5e-242 806.8 42.1 6.6e-147 491.2 11.2 2.0 1 1 1 2 2 2 2 Ewing's tumour-associated antigen 1 homologue Rotamase_2 PF13145.6 KFP01768.1 - 0.17 12.7 3.0 1.9 9.3 0.1 2.8 2 0 0 2 2 2 0 PPIC-type PPIASE domain Meis_PKNOX_N PF16493.5 KFP01769.1 - 1.7e-45 153.2 0.2 2.8e-45 152.6 0.2 1.3 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 Homeobox_KN PF05920.11 KFP01769.1 - 1.1e-20 73.2 1.0 2e-20 72.4 1.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFP01769.1 - 2.2e-08 33.8 1.2 3.7e-08 33.1 0.3 1.8 2 0 0 2 2 2 1 Homeodomain Sprouty PF05210.13 KFP01770.1 - 3e-29 101.4 25.8 3e-29 101.4 25.8 1.8 2 0 0 2 2 2 1 Sprouty protein (Spry) WH1 PF00568.23 KFP01770.1 - 2.5e-10 40.3 0.0 4.1e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 WH1 domain Actin PF00022.19 KFP01771.1 - 1.5e-112 376.2 0.0 1.2e-111 373.2 0.0 1.9 1 1 0 1 1 1 1 Actin Ras PF00071.22 KFP01772.1 - 1.8e-67 226.0 1.1 2.2e-67 225.7 1.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP01772.1 - 8.6e-38 129.2 0.1 1.6e-37 128.4 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP01772.1 - 2e-17 63.2 0.2 2.4e-17 62.9 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFP01772.1 - 5.1e-07 29.7 0.7 0.0074 16.2 0.1 2.4 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFP01772.1 - 6.6e-06 25.8 0.4 1.8e-05 24.3 0.2 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFP01772.1 - 7e-06 25.6 0.1 9.6e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP01772.1 - 8e-06 25.9 0.1 2.7e-05 24.2 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFP01772.1 - 1.4e-05 24.6 0.1 2.1e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 KFP01772.1 - 0.00079 19.8 0.0 0.12 12.8 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 KFP01772.1 - 0.0033 17.0 0.0 0.018 14.6 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KFP01772.1 - 0.018 15.5 0.0 0.022 15.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 KFP01772.1 - 0.019 14.7 0.1 0.95 9.2 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KFP01772.1 - 0.045 14.0 0.0 0.084 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFP01772.1 - 0.045 13.3 0.1 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 KFP01772.1 - 0.055 14.0 0.0 0.078 13.5 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Septin PF00735.18 KFP01772.1 - 0.06 12.6 0.1 0.14 11.5 0.0 1.6 1 1 0 1 1 1 0 Septin AAA_5 PF07728.14 KFP01772.1 - 0.063 13.3 0.0 0.12 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) LANC_like PF05147.13 KFP01772.1 - 0.074 11.6 0.1 0.16 10.5 0.0 1.5 1 1 1 2 2 2 0 Lanthionine synthetase C-like protein AAA_29 PF13555.6 KFP01772.1 - 0.075 12.8 0.2 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 KFP01772.1 - 0.14 11.5 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein Dioxygenase_N PF04444.14 KFP01772.1 - 0.16 11.8 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Catechol dioxygenase N terminus TOH_N PF12549.8 KFP01774.1 - 0.014 15.2 2.0 0.014 15.2 2.0 2.4 2 0 0 2 2 2 0 Tyrosine hydroxylase N terminal SDF PF00375.18 KFP01775.1 - 2e-96 323.4 14.5 2.4e-96 323.1 14.5 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family VMA21 PF09446.10 KFP01775.1 - 0.022 14.8 1.5 0.097 12.8 1.5 2.2 1 0 0 1 1 1 0 VMA21-like domain MH2 PF03166.14 KFP01776.1 - 1.1e-79 266.9 0.1 1.6e-79 266.4 0.1 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 KFP01776.1 - 2.8e-45 152.8 4.5 5.1e-45 151.9 4.5 1.5 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.9 KFP01776.1 - 0.006 16.4 0.0 0.0094 15.8 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 BTB PF00651.31 KFP01777.1 - 5.1e-33 113.6 1.0 1.1e-32 112.5 0.4 1.8 2 0 0 2 2 2 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFP01777.1 - 2.7e-21 75.0 32.3 8e-09 35.5 1.0 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFP01777.1 - 4.4e-14 52.1 25.0 5.2e-05 23.5 1.4 5.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP01777.1 - 2.2e-12 46.7 20.9 0.0022 18.7 0.7 5.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 KFP01777.1 - 0.0022 18.4 17.6 0.055 13.9 0.4 4.8 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zinc_ribbon_9 PF14369.6 KFP01777.1 - 0.0062 16.8 0.8 0.77 10.1 0.0 3.6 3 0 0 3 3 3 1 zinc-ribbon DUF3268 PF11672.8 KFP01777.1 - 0.031 14.6 1.5 0.37 11.1 0.9 2.6 2 0 0 2 2 2 0 zinc-finger-containing domain zf-C2H2_6 PF13912.6 KFP01777.1 - 0.044 13.8 0.1 0.044 13.8 0.1 5.1 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KFP01777.1 - 0.075 12.9 4.7 13 5.7 0.1 3.7 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 KFP01777.1 - 0.11 12.3 5.4 0.32 10.8 0.1 3.5 1 1 3 4 4 4 0 GAGA factor zf-C2H2_jaz PF12171.8 KFP01777.1 - 0.17 12.2 21.1 0.17 12.2 1.4 5.3 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFP01777.1 - 0.56 10.6 14.3 5.4 7.4 1.0 4.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) PTPRCAP PF15713.5 KFP01777.1 - 2.1 8.7 7.5 3.7 7.8 7.5 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated zf-Sec23_Sec24 PF04810.15 KFP01777.1 - 4 7.6 13.8 26 5.0 0.1 4.7 3 2 0 3 3 3 0 Sec23/Sec24 zinc finger Endonuclease_7 PF02945.15 KFP01777.1 - 5.2 7.1 10.8 3.1 7.8 3.5 3.0 1 1 1 2 2 2 0 Recombination endonuclease VII dNK PF01712.19 KFP01778.1 - 2e-35 122.5 0.0 2.5e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Deoxynucleoside kinase SKI PF01202.22 KFP01778.1 - 0.00011 22.3 0.3 0.032 14.4 0.1 2.5 3 0 0 3 3 3 2 Shikimate kinase Thymidylate_kin PF02223.17 KFP01778.1 - 0.0045 16.7 0.4 0.013 15.2 0.2 1.9 2 1 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.6 KFP01778.1 - 0.009 16.3 0.0 0.021 15.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 KFP01778.1 - 0.03 14.5 0.0 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase-like family TsaE PF02367.17 KFP01778.1 - 0.061 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 KFP01778.1 - 0.088 13.2 0.1 7.9 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 KFP01778.1 - 0.093 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase Hist_deacetyl PF00850.19 KFP01779.1 - 3.8e-84 282.8 7.5 9.2e-84 281.5 0.0 2.5 2 0 0 2 2 2 1 Histone deacetylase domain HDAC4_Gln PF12203.8 KFP01779.1 - 8e-35 118.9 46.0 8e-35 118.9 46.0 3.6 2 1 1 3 3 3 1 Glutamine rich N terminal domain of histone deacetylase 4 HLH PF00010.26 KFP01780.1 - 1.4e-15 56.9 0.6 3e-15 55.9 0.6 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_51 PF18558.1 KFP01780.1 - 0.0033 17.3 0.0 0.005 16.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain DUF773 PF05600.12 KFP01780.1 - 0.019 13.7 0.8 0.023 13.4 0.8 1.1 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 GDH_N PF12466.8 KFP01780.1 - 0.05 13.8 0.1 0.076 13.2 0.1 1.3 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal L27 PF02828.16 KFP01780.1 - 0.1 12.4 0.3 5.5 6.8 0.0 2.5 2 0 0 2 2 2 0 L27 domain Ank_2 PF12796.7 KFP01781.1 - 3.6e-21 75.5 0.2 3.9e-13 49.8 0.0 3.6 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP01781.1 - 5.5e-19 66.3 4.1 0.0008 19.7 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KFP01781.1 - 1.5e-18 66.3 4.2 0.00037 20.8 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 KFP01781.1 - 2.2e-17 62.9 0.7 6e-06 26.4 0.0 4.8 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP01781.1 - 2.5e-14 53.5 1.2 1.1e-07 32.2 0.0 4.8 2 2 2 4 4 4 3 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFP01781.1 - 3.8e-08 33.5 2.9 8e-08 32.5 2.9 1.4 1 0 0 1 1 1 1 SOCS box MIP-T3_C PF17749.1 KFP01782.1 - 1.2e-48 165.0 12.7 1.2e-48 165.0 12.7 3.9 2 1 1 3 3 3 1 Microtubule-binding protein MIP-T3 C-terminal region MIP-T3 PF10243.9 KFP01782.1 - 9.6e-18 64.2 0.1 5.9e-17 61.7 0.0 2.5 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 CH-like domain ANAPC4 PF12896.7 KFP01782.1 - 0.021 14.3 1.1 0.044 13.3 1.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 UCH PF00443.29 KFP01783.1 - 1.4e-39 136.1 1.6 4.5e-34 118.1 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP01783.1 - 9.9e-18 64.8 0.1 1.1e-16 61.3 0.1 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase YukD PF08817.10 KFP01783.1 - 0.1 13.3 0.2 4.9 7.9 0.0 3.8 5 0 0 5 5 5 0 WXG100 protein secretion system (Wss), protein YukD UDPGT PF00201.18 KFP01784.1 - 3.4e-38 131.7 0.2 3.7e-38 131.6 0.2 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.18 KFP01785.1 - 9.6e-38 130.2 0.2 1.1e-37 130.1 0.2 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.18 KFP01786.1 - 1.8e-45 155.7 0.0 2e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.18 KFP01787.1 - 2.4e-45 155.3 0.2 2.7e-45 155.1 0.2 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.18 KFP01788.1 - 1.2e-172 575.2 0.9 1.3e-89 301.3 0.1 2.1 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KFP01788.1 - 2e-05 24.6 0.0 3.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain TMEM52 PF14979.6 KFP01788.1 - 0.16 11.9 3.5 0.31 11.0 3.5 1.5 1 0 0 1 1 1 0 Transmembrane 52 Pro_3_hydrox_C PF05373.11 KFP01788.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal UPF0560 PF10577.9 KFP01788.1 - 0.38 9.2 1.9 0.51 8.8 1.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 SH3_2 PF07653.17 KFP01789.1 - 1.8e-22 78.8 0.1 8.7e-11 41.3 0.2 3.3 3 0 0 3 3 3 2 Variant SH3 domain SH3_9 PF14604.6 KFP01789.1 - 2.6e-10 40.0 0.3 2.4e-09 36.9 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFP01789.1 - 3.9e-10 39.2 0.6 2.6e-09 36.6 0.0 2.6 2 1 0 2 2 2 1 SH3 domain ZU5 PF00791.20 KFP01789.1 - 2.9e-09 37.2 0.2 5.8e-09 36.2 0.2 1.5 1 0 0 1 1 1 1 ZU5 domain Death PF00531.22 KFP01789.1 - 0.0009 19.4 2.0 0.48 10.6 0.1 3.6 2 1 1 3 3 3 2 Death domain IR1-M PF12185.8 KFP01789.1 - 0.071 13.1 0.0 2.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain Arf PF00025.21 KFP01790.1 - 3.6e-62 208.9 0.0 4e-62 208.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFP01790.1 - 6.1e-16 58.7 0.0 8.1e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP01790.1 - 1.5e-15 57.2 0.0 1.7e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFP01790.1 - 4.6e-11 42.5 0.0 7e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFP01790.1 - 2.7e-08 33.4 0.1 1.4e-05 24.5 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KFP01790.1 - 8.5e-08 32.3 0.0 1.2e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP01790.1 - 0.0003 20.4 0.1 0.00096 18.7 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFP01790.1 - 0.0022 17.4 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region 6PF2K PF01591.18 KFP01790.1 - 0.06 12.6 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase cobW PF02492.19 KFP01790.1 - 0.13 11.8 0.0 1.1 8.8 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain B_solenoid_dext PF18841.1 KFP01791.1 - 6.7 7.1 5.0 28 5.1 0.5 2.4 1 1 1 2 2 2 0 Beta solenoid repeat from Dextranase Spp-24 PF07448.11 KFP01792.1 - 1.5e-18 66.7 0.2 2.5e-18 66.0 0.2 1.4 1 0 0 1 1 1 1 Secreted phosphoprotein 24 (Spp-24) cystatin-like domain Cathelicidins PF00666.17 KFP01792.1 - 5.9e-08 32.9 0.0 8e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Cathelicidin Cystatin PF00031.21 KFP01792.1 - 0.0031 17.7 0.0 0.0048 17.1 0.0 1.2 1 0 0 1 1 1 1 Cystatin domain LSDAT_euk PF18139.1 KFP01793.1 - 1.9e-65 220.9 0.0 3.2e-65 220.2 0.0 1.3 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 KFP01793.1 - 7.5e-19 67.8 0.0 1.4e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 KFP01793.1 - 3.3e-13 49.4 21.0 3.3e-13 49.4 21.0 1.9 2 0 0 2 2 2 1 Ion transport protein ArfGap PF01412.18 KFP01794.1 - 3.4e-40 136.8 0.0 7.9e-40 135.6 0.0 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ras PF00071.22 KFP01794.1 - 2.4e-18 66.2 0.0 4.3e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Ras family Ank_2 PF12796.7 KFP01794.1 - 2.8e-11 43.9 0.1 6.1e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) PH PF00169.29 KFP01794.1 - 6.1e-11 42.8 3.2 9.5e-05 22.9 0.1 3.5 3 0 0 3 3 3 2 PH domain Ank PF00023.30 KFP01794.1 - 8.9e-10 38.6 0.0 4.1e-06 27.0 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KFP01794.1 - 3.5e-09 36.8 0.3 8.8e-09 35.5 0.3 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP01794.1 - 1.7e-07 31.7 0.1 2.2e-05 24.9 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP01794.1 - 1.2e-05 25.3 0.1 0.00049 20.3 0.0 3.0 3 0 0 3 3 2 1 Ankyrin repeat Roc PF08477.13 KFP01794.1 - 0.00043 20.5 0.0 0.0023 18.1 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase PH_6 PF15406.6 KFP01794.1 - 0.0015 18.8 0.3 0.0038 17.5 0.3 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain MAGI_u1 PF16663.5 KFP01794.1 - 0.024 14.7 0.1 0.086 12.9 0.1 2.0 1 0 0 1 1 1 0 Unstructured region on MAGI PH_11 PF15413.6 KFP01794.1 - 0.028 14.9 7.8 0.44 11.0 0.3 3.3 4 0 0 4 4 3 0 Pleckstrin homology domain PH_8 PF15409.6 KFP01794.1 - 0.067 13.5 0.6 5.9 7.2 0.1 2.9 3 0 0 3 3 3 0 Pleckstrin homology domain TniB PF05621.11 KFP01794.1 - 0.14 11.6 0.0 9.4 5.6 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein AAA PF00004.29 KFP01795.1 - 8.7e-15 55.3 0.0 2e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IQ PF00612.27 KFP01795.1 - 6.5e-06 25.5 0.7 1.4e-05 24.5 0.7 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif CSN8_PSD8_EIF3K PF10075.9 KFP01796.1 - 3.5e-35 121.1 0.0 4.4e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 KFP01796.1 - 0.018 15.5 0.0 0.028 14.9 0.0 1.3 1 0 0 1 1 1 0 PCI domain LRRFIP PF09738.9 KFP01798.1 - 4.2e-79 266.1 70.2 5.2e-43 147.6 33.8 5.4 3 1 1 4 4 4 3 LRRFIP family BRE1 PF08647.11 KFP01798.1 - 0.0043 17.1 10.9 0.0043 17.1 10.9 5.5 4 2 1 5 5 5 1 BRE1 E3 ubiquitin ligase APG6_N PF17675.1 KFP01798.1 - 0.011 16.3 10.7 0.011 16.3 10.7 5.1 3 2 1 4 4 4 0 Apg6 coiled-coil region AIP3 PF03915.13 KFP01798.1 - 0.33 10.0 34.9 0.062 12.4 15.5 2.3 2 0 0 2 2 2 0 Actin interacting protein 3 DUF4279 PF14106.6 KFP01798.1 - 0.39 10.9 0.1 0.39 10.9 0.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4279) HALZ PF02183.18 KFP01798.1 - 0.6 10.4 28.7 0.79 10.0 0.1 5.8 5 1 1 6 6 6 0 Homeobox associated leucine zipper DASH_Dam1 PF08653.10 KFP01798.1 - 1.5 8.7 3.1 4.5 7.2 0.0 3.4 4 0 0 4 4 4 0 DASH complex subunit Dam1 TPR_MLP1_2 PF07926.12 KFP01798.1 - 1.7 8.7 66.7 0.039 14.0 11.3 5.4 3 2 1 4 4 4 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.6 KFP01798.1 - 2.7 6.6 38.2 0.6 8.7 12.4 2.5 2 0 0 2 2 2 0 AAA domain DUF724 PF05266.14 KFP01798.1 - 2.7 7.8 54.1 0.093 12.5 6.9 4.9 3 2 2 5 5 5 0 Protein of unknown function (DUF724) Fib_alpha PF08702.10 KFP01798.1 - 4.3 7.5 37.4 0.84 9.8 11.3 4.2 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family UQ_con PF00179.26 KFP01800.1 - 4.3e-29 101.0 0.0 5e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-DBF PF07535.12 KFP01801.1 - 7.5e-06 26.0 9.4 7.5e-06 26.0 9.4 2.0 2 0 0 2 2 2 1 DBF zinc finger 7tm_1 PF00001.21 KFP01802.1 - 2.7e-43 148.2 23.3 3.7e-43 147.7 23.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFP01802.1 - 0.00024 20.5 5.5 0.00024 20.5 5.5 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 KFP01802.1 - 0.15 11.7 27.8 0.022 14.4 18.6 2.4 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx EF1_GNE PF00736.19 KFP01803.1 - 1.8e-37 127.4 0.3 3.4e-37 126.5 0.3 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KFP01803.1 - 1.5e-13 50.9 9.7 6.7e-13 48.8 9.7 2.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region Tnp_22_trimer PF17489.2 KFP01803.1 - 0.042 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 L1 transposable element trimerization domain YL1 PF05764.13 KFP01803.1 - 0.09 12.9 4.1 0.11 12.6 4.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Molybdopterin PF00384.22 KFP01804.1 - 4.8e-74 249.9 0.0 5.4e-73 246.4 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KFP01804.1 - 4.2e-18 65.2 0.2 1.1e-17 63.8 0.1 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 KFP01804.1 - 3.1e-17 61.8 0.1 7.8e-17 60.5 0.1 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 KFP01804.1 - 1.8e-10 41.4 0.3 3.8e-10 40.3 0.3 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 KFP01804.1 - 1.3e-09 37.9 0.4 1.3e-09 37.9 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 KFP01804.1 - 0.048 13.4 1.0 7 6.4 0.1 2.9 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain zf-C3Hc3H PF13891.6 KFP01805.1 - 1.6e-16 60.4 8.6 1.6e-16 60.4 8.6 2.2 3 0 0 3 3 3 1 Potential DNA-binding domain HemY_N PF07219.13 KFP01805.1 - 0.29 11.4 0.9 0.62 10.3 0.9 1.5 1 0 0 1 1 1 0 HemY protein N-terminus Coilin_N PF15862.5 KFP01809.1 - 0.2 11.4 11.9 0.27 11.0 11.9 1.3 1 0 0 1 1 1 0 Coilin N-terminus RR_TM4-6 PF06459.12 KFP01809.1 - 0.28 11.0 9.9 0.29 10.9 9.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KFP01809.1 - 1 8.0 6.0 1.1 8.0 6.0 1.1 1 0 0 1 1 1 0 Presenilin RNA_polI_A34 PF08208.11 KFP01809.1 - 2.3 8.2 26.4 3.1 7.8 26.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Zip PF02535.22 KFP01809.1 - 3.9 6.6 6.7 4.5 6.4 6.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Connexin PF00029.19 KFP01809.1 - 5.5 6.7 6.2 6.5 6.4 6.2 1.2 1 0 0 1 1 1 0 Connexin PDZ PF00595.24 KFP01810.1 - 1.2e-21 76.8 0.2 1.8e-18 66.7 0.2 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFP01810.1 - 4.5e-13 48.8 0.1 8.6e-10 38.3 0.1 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFP01810.1 - 7.6e-10 39.0 0.0 1.8e-08 34.5 0.0 2.2 2 0 0 2 2 2 1 PDZ domain FAD_binding_1 PF00667.20 KFP01811.1 - 4.4e-80 268.4 0.0 7.2e-80 267.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFP01811.1 - 3.8e-40 137.4 0.2 1.8e-39 135.2 0.3 2.1 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 KFP01811.1 - 4.1e-19 69.2 0.1 2.4e-18 66.8 0.0 2.3 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain DUF4761 PF15958.5 KFP01811.1 - 0.021 15.0 0.1 2.3 8.4 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4761) NAD_binding_6 PF08030.12 KFP01811.1 - 0.042 14.0 0.0 0.095 12.8 0.0 1.6 1 1 0 1 1 1 0 Ferric reductase NAD binding domain Glyco_tran_WecB PF03808.13 KFP01811.1 - 0.15 12.0 0.0 0.76 9.7 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family TMPIT PF07851.13 KFP01812.1 - 6.2e-153 508.8 18.6 7e-153 508.6 18.6 1.0 1 0 0 1 1 1 1 TMPIT-like protein Atg14 PF10186.9 KFP01812.1 - 0.079 12.0 3.1 0.11 11.6 3.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DSPc PF00782.20 KFP01813.1 - 3.1e-24 85.3 0.0 5.2e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 KFP01813.1 - 0.00028 21.4 0.0 0.0059 17.1 0.0 2.5 1 1 0 1 1 1 1 Rhodanese-like domain Ldh_1_N PF00056.23 KFP01814.1 - 4.3e-49 166.2 0.0 6.4e-49 165.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KFP01814.1 - 2e-44 151.4 0.1 7.4e-44 149.6 0.1 2.0 2 1 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Semialdhyde_dh PF01118.24 KFP01814.1 - 0.00025 21.5 0.0 0.0036 17.7 0.0 2.3 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KFP01814.1 - 0.0015 17.6 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KFP01814.1 - 0.0018 18.2 0.0 0.04 13.8 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H-binding DapB_N PF01113.20 KFP01814.1 - 0.013 15.6 0.0 0.049 13.8 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus THF_DHG_CYH_C PF02882.19 KFP01814.1 - 0.022 14.1 0.2 0.18 11.1 0.0 2.5 2 1 1 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_trans_1_4 PF13692.6 KFP01814.1 - 0.067 13.6 0.1 0.72 10.3 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferases group 1 HSP20 PF00011.21 KFP01815.1 - 2.7e-13 49.9 0.3 3.6e-13 49.5 0.3 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family YabP PF07873.11 KFP01815.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 YabP family 14-3-3 PF00244.20 KFP01816.1 - 5.1e-96 320.5 7.1 5.7e-96 320.3 7.1 1.0 1 0 0 1 1 1 1 14-3-3 protein Peptidase_C98 PF15499.6 KFP01816.1 - 0.072 12.5 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase FlaC_arch PF05377.11 KFP01816.1 - 0.14 12.5 0.8 0.34 11.3 0.8 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DTC PF18102.1 KFP01817.1 - 5.4e-60 201.3 0.0 1e-59 200.5 0.0 1.5 1 0 0 1 1 1 1 Deltex C-terminal domain WWE PF02825.20 KFP01817.1 - 2.1e-34 117.9 0.5 9.9e-16 58.1 0.0 2.5 2 0 0 2 2 2 2 WWE domain zf-C3HC4 PF00097.25 KFP01817.1 - 5.6e-05 22.9 9.1 0.00013 21.7 9.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP01817.1 - 8.8e-05 22.4 2.1 0.0003 20.8 2.1 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KFP01817.1 - 0.0029 17.9 6.0 0.0061 16.8 6.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-UDP PF14569.6 KFP01817.1 - 0.0098 16.0 0.9 0.028 14.5 0.9 1.8 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-RING_11 PF17123.5 KFP01817.1 - 0.011 15.4 6.6 0.13 12.0 0.1 2.6 2 0 0 2 2 2 0 RING-like zinc finger zf-ANAPC11 PF12861.7 KFP01817.1 - 0.02 14.9 1.5 0.071 13.2 1.5 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KFP01817.1 - 0.024 14.5 3.2 0.024 14.5 3.2 3.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP01817.1 - 0.065 13.2 11.4 0.029 14.3 8.3 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-Nse PF11789.8 KFP01817.1 - 0.086 12.7 1.0 0.2 11.5 1.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.6 KFP01817.1 - 0.16 12.3 17.6 0.029 14.7 11.3 2.8 2 1 0 2 2 2 0 Ring finger domain MHC2-interact PF09307.10 KFP01818.1 - 0.099 12.6 0.0 3.2 7.8 0.0 2.2 2 0 0 2 2 2 0 CLIP, MHC2 interacting C2 PF00168.30 KFP01819.1 - 4.5e-44 149.0 0.0 9e-26 90.2 0.0 2.3 2 0 0 2 2 2 2 C2 domain RasGAP PF00616.19 KFP01819.1 - 6.4e-32 111.0 0.0 2.4e-31 109.1 0.0 1.8 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RNA_pol_L_2 PF13656.6 KFP01820.1 - 1.2e-29 101.8 0.1 1.5e-29 101.5 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KFP01820.1 - 1.3e-10 40.5 0.0 1.8e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SHNi-TPR PF10516.9 KFP01820.1 - 0.12 11.9 0.1 0.39 10.2 0.0 1.8 1 1 1 2 2 2 0 SHNi-TPR LRR_4 PF12799.7 KFP01821.1 - 7.6e-08 32.5 6.1 7.6e-08 32.5 6.1 3.0 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP01821.1 - 2.8e-06 27.0 10.2 0.0021 17.8 2.4 2.8 1 1 0 2 2 2 2 Leucine rich repeat WD40 PF00400.32 KFP01821.1 - 0.00098 19.9 0.4 0.031 15.2 0.0 3.6 4 0 0 4 4 4 1 WD domain, G-beta repeat LRR_9 PF14580.6 KFP01821.1 - 0.037 13.5 4.3 0.065 12.7 4.3 1.3 1 0 0 1 1 1 0 Leucine-rich repeat LRR_1 PF00560.33 KFP01821.1 - 9.1 7.3 10.7 5.3 8.0 1.2 4.0 3 0 0 3 3 3 0 Leucine Rich Repeat 2OG-FeII_Oxy_2 PF13532.6 KFP01822.1 - 7.5e-05 23.0 0.0 0.00012 22.4 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Orai-1 PF07856.12 KFP01823.1 - 1.1e-71 240.1 6.8 1.3e-71 239.8 6.8 1.1 1 0 0 1 1 1 1 Mediator of CRAC channel activity CopD PF05425.13 KFP01823.1 - 0.061 13.7 2.8 1 9.8 0.0 2.3 1 1 1 2 2 2 0 Copper resistance protein D DUF2207 PF09972.9 KFP01823.1 - 0.14 10.9 1.5 0.22 10.2 1.5 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Asp5 PF17000.5 KFP01823.1 - 0.48 10.6 7.3 0.13 12.4 0.9 2.2 2 0 0 2 2 2 0 Accessory secretory protein Sec, Asp5 DUF1168 PF06658.12 KFP01824.1 - 2.3e-47 160.2 23.4 2.9e-47 159.9 23.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Caldesmon PF02029.15 KFP01824.1 - 0.0058 15.4 25.2 0.0068 15.2 25.2 1.0 1 0 0 1 1 1 1 Caldesmon BPL_N PF09825.9 KFP01824.1 - 0.13 11.4 9.4 0.16 11.0 9.4 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal FAM60A PF15396.6 KFP01824.1 - 0.13 12.2 12.1 0.17 11.9 12.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Spem1 PF15670.5 KFP01824.1 - 0.2 11.2 8.5 0.26 10.8 8.5 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 CNDH2_C PF16858.5 KFP01824.1 - 0.84 9.4 20.1 1.1 9.1 20.1 1.0 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Vfa1 PF08432.10 KFP01824.1 - 0.96 9.8 24.2 1.2 9.4 24.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GAGA_bind PF06217.12 KFP01824.1 - 1.4 9.1 14.8 1.6 8.9 14.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 KFP01824.1 - 1.5 8.6 18.1 1.9 8.3 18.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DASH_Spc19 PF08287.11 KFP01824.1 - 1.6 8.6 21.8 2.1 8.2 21.8 1.1 1 0 0 1 1 1 0 Spc19 DUF4746 PF15928.5 KFP01824.1 - 1.9 7.9 19.9 2.3 7.6 19.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CobT PF06213.12 KFP01824.1 - 2.3 7.5 24.4 3.1 7.1 24.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RNA_pol_3_Rpc31 PF11705.8 KFP01824.1 - 3.1 8.0 23.7 4 7.6 23.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DDHD PF02862.17 KFP01824.1 - 3.6 7.7 10.1 4.6 7.3 10.1 1.2 1 0 0 1 1 1 0 DDHD domain Spore_coat_CotO PF14153.6 KFP01824.1 - 4.5 7.2 23.8 5.8 6.8 23.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO SAPS PF04499.15 KFP01824.1 - 5.3 5.7 16.0 6.3 5.5 16.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RP-C_C PF11800.8 KFP01824.1 - 6.1 6.9 14.0 8.6 6.4 14.0 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region VIR_N PF15912.5 KFP01824.1 - 6.9 6.2 14.5 8.5 5.9 14.5 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Neur_chan_memb PF02932.16 KFP01824.1 - 7.5 6.5 9.3 9.1 6.3 9.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region V_ATPase_I PF01496.19 KFP01824.1 - 8.5 4.2 14.5 9.4 4.0 14.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CUT PF02376.15 KFP01825.1 - 1.6e-78 258.9 0.0 5.1e-25 87.4 0.0 3.9 3 0 0 3 3 3 3 CUT domain Homeodomain PF00046.29 KFP01825.1 - 3.3e-15 55.6 0.7 3.3e-15 55.6 0.7 2.6 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KFP01825.1 - 1.2e-05 25.1 0.6 4.5e-05 23.3 0.6 2.1 1 0 0 1 1 1 1 Homeobox KN domain DUF5572 PF17733.1 KFP01825.1 - 0.0015 18.3 0.0 26 4.7 0.0 4.0 3 0 0 3 3 3 0 Family of unknown function (DUF5572) NPV_P10 PF05531.12 KFP01825.1 - 0.025 15.1 12.8 0.029 14.8 1.3 3.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein HTH_40 PF14493.6 KFP01825.1 - 0.034 14.6 5.9 5.3 7.6 0.4 3.8 3 0 0 3 3 3 0 Helix-turn-helix domain DUF4618 PF15397.6 KFP01825.1 - 4.5 6.6 38.1 0.048 13.1 23.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) EF-hand_1 PF00036.32 KFP01826.1 - 1.2e-14 52.6 3.7 5.1e-06 25.7 0.9 3.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFP01826.1 - 1.2e-10 40.4 3.4 2e-06 27.2 0.8 3.1 2 1 1 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KFP01826.1 - 2e-10 40.9 0.2 9.2e-05 22.8 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFP01826.1 - 2.3e-08 33.8 1.2 0.015 15.1 0.1 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KFP01826.1 - 0.00043 19.6 2.2 0.0017 17.7 1.0 2.6 2 0 0 2 2 2 1 EF hand 3Beta_HSD PF01073.19 KFP01827.1 - 1e-49 169.0 0.0 1.2e-49 168.8 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFP01827.1 - 1.8e-10 40.7 0.0 2.4e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KFP01827.1 - 3.1e-07 29.8 0.0 3.8e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Collagen PF01391.18 KFP01828.1 - 1.1e-19 70.0 75.8 3.4e-09 36.3 30.2 3.4 2 1 0 2 2 2 2 Collagen triple helix repeat (20 copies) EMI PF07546.13 KFP01828.1 - 4.4e-18 65.8 11.0 8.7e-18 64.8 11.0 1.5 1 0 0 1 1 1 1 EMI domain Roc PF08477.13 KFP01829.1 - 4.3e-09 36.6 0.0 5.9e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP01829.1 - 1.4e-06 28.0 0.0 1.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KFP01829.1 - 0.014 14.9 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family RILP PF11461.8 KFP01830.1 - 8.7e-21 73.9 6.1 8.7e-21 73.9 6.1 2.9 3 1 0 3 3 3 1 Rab interacting lysosomal protein DIRP PF06584.13 KFP01830.1 - 0.0043 17.2 0.5 0.0043 17.2 0.5 2.7 2 1 1 3 3 3 1 DIRP Leu_zip PF15294.6 KFP01830.1 - 0.0044 16.6 11.4 0.006 16.1 11.4 1.3 1 0 0 1 1 1 1 Leucine zipper Takusan PF04822.13 KFP01830.1 - 0.06 13.2 0.9 0.06 13.2 0.9 3.3 2 1 1 3 3 3 0 Takusan Kinesin_assoc PF16183.5 KFP01830.1 - 0.081 13.1 1.6 0.74 9.9 1.3 2.1 2 0 0 2 2 2 0 Kinesin-associated Nas2_N PF18265.1 KFP01830.1 - 0.089 12.7 4.0 3.8 7.5 0.2 3.1 1 1 3 4 4 4 0 Nas2 N_terminal domain Ovate PF04844.13 KFP01830.1 - 0.097 12.7 0.1 0.28 11.2 0.1 1.8 1 0 0 1 1 1 0 Transcriptional repressor, ovate NPV_P10 PF05531.12 KFP01830.1 - 0.24 11.9 2.2 2 8.9 0.9 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein W2 PF02020.18 KFP01830.1 - 0.37 10.9 5.5 0.13 12.4 2.2 1.9 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon Striatin PF08232.12 KFP01830.1 - 1.1 9.8 14.3 0.61 10.7 11.2 1.9 2 0 0 2 2 2 0 Striatin family Jnk-SapK_ap_N PF09744.9 KFP01830.1 - 3 8.0 21.4 1.6 9.0 0.7 3.3 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 DivIVA PF05103.13 KFP01830.1 - 4.5 7.4 15.9 1.3 9.2 5.2 2.6 2 1 0 2 2 2 0 DivIVA protein Atg14 PF10186.9 KFP01830.1 - 6.3 5.8 16.8 3.3 6.7 13.7 1.8 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 PROCN PF08083.11 KFP01831.1 - 4.9e-237 786.3 8.2 4.9e-237 786.3 8.2 1.6 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KFP01831.1 - 2.2e-130 433.2 0.6 3.9e-130 432.4 0.6 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KFP01831.1 - 9.5e-90 298.6 3.4 2.2e-89 297.5 3.4 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KFP01831.1 - 3.8e-87 289.9 5.4 3.9e-87 289.9 3.7 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KFP01831.1 - 3.9e-74 247.1 0.0 7.9e-74 246.1 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 KFP01831.1 - 4.2e-54 181.7 0.0 1e-53 180.5 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 KFP01831.1 - 2.9e-47 158.9 0.5 7.6e-47 157.6 0.5 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 KFP01831.1 - 1.5e-13 50.8 0.0 4.2e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease WD40 PF00400.32 KFP01833.1 - 2.3e-15 56.7 5.7 1.6e-06 28.7 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP01833.1 - 0.0055 17.0 0.0 0.31 11.4 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KFP01833.1 - 0.038 13.6 0.0 0.24 11.0 0.0 2.3 3 0 0 3 3 3 0 PQQ-like domain Nup160 PF11715.8 KFP01833.1 - 0.092 11.4 0.0 0.2 10.3 0.0 1.5 1 0 0 1 1 1 0 Nucleoporin Nup120/160 BAF1_ABF1 PF04684.13 KFP01833.1 - 0.49 9.4 4.9 0.7 8.9 4.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Myc_N PF01056.18 KFP01833.1 - 2.4 8.0 8.6 3.8 7.3 8.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region BSP_II PF05432.11 KFP01833.1 - 3 7.5 12.6 4.5 6.9 12.6 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Serpin PF00079.20 KFP01834.1 - 1.2e-89 301.3 1.8 1.3e-89 301.1 1.8 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFP01835.1 - 9e-85 285.2 0.1 1e-84 285.0 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Rep_fac-A_C PF08646.10 KFP01836.1 - 1.1e-54 184.2 13.3 2.3e-51 173.4 8.5 2.8 3 0 0 3 3 3 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KFP01836.1 - 2.4e-39 133.2 1.0 3.8e-37 126.1 0.5 2.4 2 0 0 2 2 2 2 Replication protein A OB domain Rep-A_N PF04057.12 KFP01836.1 - 7.1e-28 96.6 0.2 1.3e-27 95.8 0.2 1.4 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KFP01836.1 - 4.7e-13 48.9 0.5 3.6e-11 42.9 0.0 3.3 2 1 1 3 3 3 1 OB-fold nucleic acid binding domain DUF5521 PF17659.1 KFP01836.1 - 0.00061 17.8 0.1 0.0022 15.9 0.0 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5521) DUF4939 PF16297.5 KFP01836.1 - 0.026 14.4 0.1 0.15 11.9 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4939) DUF223 PF02721.14 KFP01836.1 - 0.05 13.9 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF223 IBR PF01485.21 KFP01836.1 - 0.11 12.7 3.8 0.3 11.3 3.8 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain FSH1 PF03959.13 KFP01837.1 - 1.1e-51 175.5 0.0 1.3e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KFP01837.1 - 0.038 13.8 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.13 KFP01837.1 - 0.087 12.7 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Serine hydrolase BTB PF00651.31 KFP01838.1 - 8.5e-25 87.1 0.0 1.2e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 KFP01838.1 - 1.6e-24 84.9 27.1 8.2e-06 26.0 1.7 6.1 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP01838.1 - 1.6e-23 81.4 21.1 0.00018 22.0 0.6 6.1 6 0 0 6 6 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP01838.1 - 2.5e-20 71.9 24.0 2e-07 31.1 0.1 6.6 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFP01838.1 - 2.2e-15 56.5 2.3 0.00051 20.3 0.2 5.6 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP01838.1 - 1.2e-11 44.3 21.1 0.009 16.0 0.3 6.1 5 1 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 KFP01838.1 - 1.5e-10 41.1 15.0 0.014 15.8 0.4 6.1 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 KFP01838.1 - 2.2e-06 28.4 6.1 0.00025 21.7 0.3 3.9 1 1 2 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 KFP01838.1 - 2.9e-05 23.7 18.2 0.14 11.9 0.3 5.7 6 0 0 6 6 6 3 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KFP01838.1 - 0.00012 22.4 17.3 1.2 9.5 8.0 5.5 3 1 2 5 5 4 3 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 KFP01838.1 - 0.0011 19.2 12.2 0.04 14.2 0.7 3.4 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 KFP01838.1 - 0.0017 18.6 8.8 0.4 11.0 0.0 3.6 2 1 1 3 3 3 1 C2H2-type zinc ribbon zf_UBZ PF18439.1 KFP01838.1 - 0.0021 17.6 8.7 17 5.1 0.0 5.2 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFP01838.1 - 0.014 15.5 13.1 0.15 12.2 1.1 4.4 2 1 1 3 3 3 0 Zinc ribbon domain zf_C2H2_ZHX PF18387.1 KFP01838.1 - 0.034 13.8 7.0 2.1 8.1 0.2 3.6 4 0 0 4 4 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_9 PF16293.5 KFP01838.1 - 0.035 13.9 2.2 12 5.9 0.0 3.9 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_15 PF17032.5 KFP01838.1 - 0.054 14.2 4.6 22 5.9 0.1 3.2 1 1 2 3 3 3 0 zinc-ribbon family GAGA PF09237.11 KFP01838.1 - 0.11 12.3 0.6 2.8 7.8 0.0 2.5 2 0 0 2 2 2 0 GAGA factor zf-UBP PF02148.19 KFP01838.1 - 0.11 12.8 11.1 1.2 9.5 0.2 3.5 2 1 1 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein LIM PF00412.22 KFP01838.1 - 0.43 10.8 9.1 0.28 11.5 0.3 3.6 2 1 2 4 4 4 0 LIM domain zf-H2C2_5 PF13909.6 KFP01838.1 - 0.57 10.0 24.3 5.5 6.8 0.5 4.9 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-C2HE PF16278.5 KFP01838.1 - 2.1 8.8 13.3 22 5.6 0.5 4.9 2 1 3 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger zinc-ribbons_6 PF07191.12 KFP01838.1 - 5.3 7.1 8.0 24 5.0 0.5 3.8 1 1 2 3 3 3 0 zinc-ribbons HNH_5 PF14279.6 KFP01838.1 - 5.3 7.0 9.2 34 4.4 0.0 4.5 4 1 0 4 4 4 0 HNH endonuclease zf-HYPF PF07503.12 KFP01838.1 - 6 6.7 9.1 13 5.6 1.5 3.7 3 1 0 3 3 3 0 HypF finger EST1_DNA_bind PF10373.9 KFP01839.1 - 1.1e-59 202.3 0.7 3e-59 200.8 0.0 2.0 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain PIN_4 PF13638.6 KFP01839.1 - 1.5e-20 73.8 0.0 1.5e-20 73.8 0.0 2.9 3 0 0 3 3 3 1 PIN domain EST1 PF10374.9 KFP01839.1 - 1.2e-15 58.4 2.1 2.8e-15 57.1 0.5 2.7 2 0 0 2 2 2 1 Telomerase activating protein Est1 PIN_9 PF18477.1 KFP01839.1 - 0.0024 18.1 0.4 0.33 11.3 0.0 3.3 3 0 0 3 3 3 1 PIN like domain PKI PF02827.16 KFP01839.1 - 0.051 13.8 2.8 0.4 10.9 2.8 2.6 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor TPR_2 PF07719.17 KFP01839.1 - 0.41 10.9 1.8 5.5 7.4 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat PALP PF00291.25 KFP01841.1 - 1.6e-78 264.1 0.9 1.8e-78 263.9 0.9 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme RIBIOP_C PF04950.12 KFP01842.1 - 5.6e-127 423.2 0.0 5.6e-127 423.2 0.0 1.5 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KFP01842.1 - 2.5e-20 72.4 0.0 5.8e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain CDC45 PF02724.14 KFP01842.1 - 3.8 5.7 8.3 5.2 5.2 8.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF525 PF04379.14 KFP01843.1 - 4.2e-27 94.2 0.1 7.2e-27 93.5 0.1 1.4 1 0 0 1 1 1 1 ApaG domain YccV-like PF08755.11 KFP01843.1 - 5.1e-13 49.3 0.4 2.8e-12 47.0 0.0 2.1 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Vma12 PF11712.8 KFP01844.1 - 4.3e-25 88.4 0.0 5.1e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Kinesin PF00225.23 KFP01845.1 - 5.6e-90 301.6 0.0 6.7e-90 301.4 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFP01845.1 - 1.7e-17 63.8 0.0 2.4e-16 60.0 0.0 2.2 1 1 0 1 1 1 1 Microtubule binding Prp19 PF08606.11 KFP01845.1 - 0.14 12.2 0.2 0.27 11.2 0.2 1.4 1 0 0 1 1 1 0 Prp19/Pso4-like Hemopexin PF00045.19 KFP01846.1 - 3.4e-49 164.6 19.1 3.3e-16 59.0 0.1 5.3 5 0 0 5 5 5 4 Hemopexin Somatomedin_B PF01033.17 KFP01846.1 - 8.8e-10 38.8 19.0 1.6e-09 38.0 19.0 1.5 1 0 0 1 1 1 1 Somatomedin B domain SAM_2 PF07647.17 KFP01847.1 - 2.3e-30 104.5 0.9 9e-17 61.0 0.1 2.9 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFP01847.1 - 3.7e-19 68.9 0.3 1.2e-13 51.3 0.1 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) TIR_2 PF13676.6 KFP01847.1 - 2.3e-13 50.8 0.1 1.3e-12 48.3 0.0 2.3 2 0 0 2 2 2 1 TIR domain SAM_3 PF18016.1 KFP01847.1 - 2e-05 24.3 0.0 8.4e-05 22.3 0.0 2.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) MFS_1 PF07690.16 KFP01848.1 - 6.3e-14 51.7 29.1 6.3e-14 51.7 29.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Na_sulph_symp PF00939.19 KFP01849.1 - 1.6e-123 413.2 16.7 2e-123 412.9 16.7 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KFP01849.1 - 2.1e-24 86.3 32.7 2e-14 53.5 12.2 3.1 3 0 0 3 3 3 2 Citrate transporter Forkhead PF00250.18 KFP01850.1 - 1.5e-34 118.1 1.4 1.6e-34 118.0 0.2 1.8 2 0 0 2 2 2 1 Forkhead domain GMP_PDE_delta PF05351.11 KFP01851.1 - 4.6e-79 264.0 3.1 5.2e-79 263.8 3.1 1.0 1 0 0 1 1 1 1 GMP-PDE, delta subunit IIGP PF05049.13 KFP01851.1 - 0.11 11.5 0.2 0.15 11.1 0.2 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) PIG-S PF10510.9 KFP01852.1 - 3.3e-114 382.6 0.2 3.7e-114 382.4 0.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Glycolytic PF00274.19 KFP01853.1 - 1.3e-185 616.1 0.0 1.5e-185 615.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Paramyx_P_V_C PF03210.13 KFP01854.1 - 0.02 14.7 0.3 0.026 14.3 0.3 1.3 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal HMMR_C PF15908.5 KFP01854.1 - 0.59 10.4 8.5 0.76 10.0 1.4 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal APG6_N PF17675.1 KFP01854.1 - 1.8 9.1 14.7 2.5 8.6 14.7 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Fib_alpha PF08702.10 KFP01854.1 - 5.3 7.2 7.6 17 5.6 2.9 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Pkinase PF00069.25 KFP01855.1 - 7.8e-39 133.6 0.0 8.4e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP01855.1 - 3e-18 66.0 0.0 3.5e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP01855.1 - 3.6e-06 26.5 0.2 1.1e-05 24.9 0.1 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFP01855.1 - 0.0012 18.3 0.3 0.0014 18.0 0.3 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFP01855.1 - 0.0012 17.8 0.2 0.0025 16.8 0.2 1.2 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KFP01855.1 - 0.0018 17.1 0.1 0.0025 16.7 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 KFP01855.1 - 0.028 13.5 0.0 0.089 11.8 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 APH PF01636.23 KFP01855.1 - 0.03 14.2 0.2 0.037 13.9 0.2 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family MIR PF02815.19 KFP01856.1 - 3e-08 33.8 0.1 4.7e-07 29.8 0.1 2.0 1 1 1 2 2 2 2 MIR domain SH2_2 PF14633.6 KFP01857.1 - 4.9e-82 274.5 0.3 4.9e-82 274.5 0.3 2.2 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.6 KFP01857.1 - 2e-71 238.6 0.0 6.5e-71 237.0 0.0 2.0 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 KFP01857.1 - 2e-50 169.5 0.1 4.7e-50 168.3 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.6 KFP01857.1 - 4.6e-26 91.5 2.1 1.4e-25 89.9 2.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 KFP01857.1 - 9.5e-16 58.2 30.7 9.5e-16 58.2 30.7 8.1 7 1 2 9 9 7 2 Acidic N-terminal SPT6 Tex_N PF09371.10 KFP01857.1 - 1.6e-08 34.4 0.0 0.0056 16.4 0.0 3.2 2 1 0 2 2 2 2 Tex-like protein N-terminal domain HHH_3 PF12836.7 KFP01857.1 - 1.3e-07 31.8 0.0 4.6e-07 30.0 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif S1 PF00575.23 KFP01857.1 - 2e-06 28.0 0.1 5.7e-06 26.6 0.1 1.8 1 0 0 1 1 1 1 S1 RNA binding domain SH2 PF00017.24 KFP01857.1 - 4.3e-06 26.7 0.0 1.2e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 SH2 domain HHH_9 PF17674.1 KFP01857.1 - 1.1e-05 26.3 0.1 7.7e-05 23.5 0.1 2.7 1 0 0 1 1 1 1 HHH domain Tex_YqgF PF16921.5 KFP01857.1 - 0.00025 21.5 0.0 0.00054 20.4 0.0 1.5 1 0 0 1 1 1 1 Tex protein YqgF-like domain zf-Sec23_Sec24 PF04810.15 KFP01857.1 - 0.16 12.1 0.2 0.47 10.6 0.2 1.7 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Ras PF00071.22 KFP01858.1 - 3.5e-46 156.8 0.1 3.9e-46 156.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP01858.1 - 4.1e-31 107.7 0.0 6.1e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP01858.1 - 2.7e-16 59.5 0.0 3.2e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP01858.1 - 1.4e-07 31.6 0.0 2.6e-07 30.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFP01858.1 - 1.7e-05 24.3 0.0 2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFP01858.1 - 0.00018 21.0 0.0 0.00021 20.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KFP01858.1 - 0.0012 18.4 0.1 0.4 10.2 0.0 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 KFP01858.1 - 0.0045 17.0 0.0 0.0064 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 KFP01858.1 - 0.0046 17.0 0.0 0.62 10.1 0.0 2.7 2 1 1 3 3 3 1 Dynamin family TniB PF05621.11 KFP01858.1 - 0.03 13.8 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein DUF695 PF05117.12 KFP01858.1 - 0.047 13.9 0.0 0.083 13.1 0.0 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF695) RsgA_GTPase PF03193.16 KFP01858.1 - 0.073 13.0 0.1 9.7 6.1 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase cobW PF02492.19 KFP01858.1 - 0.12 11.9 0.1 2.8 7.5 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KFP01858.1 - 0.16 11.7 0.0 0.59 9.9 0.0 1.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation TRAM_LAG1_CLN8 PF03798.16 KFP01859.1 - 6.9e-16 58.6 11.4 8.2e-16 58.3 11.4 1.1 1 0 0 1 1 1 1 TLC domain Pkinase PF00069.25 KFP01860.1 - 1.1e-59 202.0 0.1 1.6e-59 201.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain RCC1 PF00415.18 KFP01860.1 - 7.6e-46 154.5 24.5 7.2e-12 45.7 0.6 8.1 7 1 1 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.17 KFP01860.1 - 2e-41 142.0 0.0 3.3e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1_2 PF13540.6 KFP01860.1 - 1.6e-19 69.2 30.5 6.5e-06 25.8 0.2 6.8 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Kinase-like PF14531.6 KFP01860.1 - 0.00015 21.2 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFP01860.1 - 0.00036 19.6 0.8 0.00058 18.9 0.8 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFP01860.1 - 0.016 15.1 1.5 0.069 13.1 0.8 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFP01860.1 - 0.1 11.4 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase MATH PF00917.26 KFP01861.1 - 3.2e-05 24.0 0.0 0.022 14.9 0.0 2.0 1 1 1 2 2 2 2 MATH domain FAM222A PF15258.6 KFP01862.1 - 1.1e-280 932.3 39.1 1.2e-280 932.1 39.1 1.0 1 0 0 1 1 1 1 Protein family of FAM222A MMR_HSR1 PF01926.23 KFP01863.1 - 1e-21 77.2 0.0 1.5e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KFP01863.1 - 9.8e-11 42.0 0.4 1e-05 25.7 0.1 2.2 2 0 0 2 2 2 2 Dynamin family FeoB_N PF02421.18 KFP01863.1 - 4.4e-09 36.0 0.0 6.9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KFP01863.1 - 1.9e-08 34.1 0.0 0.00046 19.8 0.0 2.9 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain KH_2 PF07650.17 KFP01863.1 - 2.2e-08 33.8 0.0 3.6e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 KH domain AIG1 PF04548.16 KFP01863.1 - 7.5e-08 32.0 0.0 1.1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KFP01863.1 - 8.1e-07 29.1 0.2 0.0027 17.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 KFP01863.1 - 0.00028 21.2 0.0 0.024 14.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain cobW PF02492.19 KFP01863.1 - 0.00035 20.2 0.5 0.002 17.8 0.1 1.9 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.22 KFP01863.1 - 0.00079 19.1 0.0 0.0035 16.9 0.0 1.9 1 1 0 1 1 1 1 Ras family GBP PF02263.19 KFP01863.1 - 0.0018 17.6 0.1 0.013 14.8 0.1 2.0 1 1 0 1 1 1 1 Guanylate-binding protein, N-terminal domain KH_1 PF00013.29 KFP01863.1 - 0.0022 17.8 0.1 0.0044 16.8 0.1 1.4 1 0 0 1 1 1 1 KH domain G-alpha PF00503.20 KFP01863.1 - 0.0032 16.7 0.2 1.4 8.0 0.1 2.1 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.21 KFP01863.1 - 0.0043 16.5 0.3 0.08 12.4 0.3 2.2 1 1 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 KFP01863.1 - 0.0053 16.6 0.2 0.038 13.8 0.1 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Roc PF08477.13 KFP01863.1 - 0.0068 16.6 0.0 0.1 12.8 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KFP01863.1 - 0.11 11.9 0.0 0.29 10.5 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_18 PF13238.6 KFP01863.1 - 0.12 12.9 0.0 0.27 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Band_7 PF01145.25 KFP01864.1 - 1.3e-19 70.9 0.1 1.3e-19 70.9 0.1 2.5 2 1 0 2 2 2 1 SPFH domain / Band 7 family Flot PF15975.5 KFP01864.1 - 3.3e-11 43.4 6.1 3.3e-11 43.4 6.1 3.4 1 1 2 4 4 4 2 Flotillin YjbH PF06082.11 KFP01864.1 - 0.32 9.7 5.8 0.43 9.3 5.8 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Sushi PF00084.20 KFP01866.1 - 1.3e-33 115.3 13.9 8.8e-11 42.2 2.7 4.3 4 0 0 4 4 4 4 Sushi repeat (SCR repeat) CUB PF00431.20 KFP01866.1 - 1.2e-16 61.0 0.0 2.1e-15 57.0 0.0 2.3 2 0 0 2 2 2 1 CUB domain SKG6 PF08693.10 KFP01866.1 - 0.12 11.8 0.8 0.22 10.9 0.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain cEGF PF12662.7 KFP01866.1 - 1.7 8.6 12.1 1.3 9.0 0.1 4.1 4 1 0 4 4 4 0 Complement Clr-like EGF-like Myosin_head PF00063.21 KFP01868.1 - 5.5e-76 256.2 0.0 1.6e-41 142.4 0.0 4.1 4 0 0 4 4 4 3 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KFP01868.1 - 1.4e-18 66.2 178.8 9.2e-15 53.6 103.0 4.1 1 1 1 2 2 2 2 Myosin tail PDZ PF00595.24 KFP01868.1 - 1.4e-09 38.2 0.0 4e-09 36.7 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP01868.1 - 7.7e-09 35.3 0.3 2.2e-08 33.8 0.3 1.8 1 0 0 1 1 1 1 PDZ domain IQ PF00612.27 KFP01868.1 - 0.00013 21.4 2.7 0.00018 21.0 0.2 2.6 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_16 PF13191.6 KFP01868.1 - 0.085 13.2 0.0 0.085 13.2 0.0 6.6 5 1 1 6 6 6 0 AAA ATPase domain AAA_5 PF07728.14 KFP01868.1 - 0.19 11.7 4.0 5.9 6.9 0.0 3.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF1843 PF08898.10 KFP01868.1 - 1.1 9.8 9.5 3.4 8.3 3.9 4.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) RsgA_GTPase PF03193.16 KFP01868.1 - 4.5 7.1 6.5 2.2 8.1 0.0 3.8 4 1 0 4 4 4 0 RsgA GTPase Crystall PF00030.19 KFP01869.1 - 9.2e-60 198.8 6.5 6.5e-30 103.2 0.3 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.13 KFP01869.1 - 0.0039 17.1 1.3 0.93 9.5 0.0 2.8 2 1 0 2 2 2 2 Peptidase inhibitor family I36 IL4_i_Ig PF18258.1 KFP01869.1 - 0.02 15.1 5.9 29 5.0 0.0 4.0 1 1 2 4 4 4 0 Interleukin-4 inducing immunoglobulin-binding domain NUFIP2 PF15293.6 KFP01870.1 - 3.1e-303 1007.2 25.4 3.5e-303 1007.1 25.4 1.0 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 2 Pkinase PF00069.25 KFP01871.1 - 3.1e-65 220.2 0.0 3.1e-65 220.2 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP01871.1 - 2.3e-44 151.6 1.2 4.9e-44 150.6 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFP01871.1 - 0.022 14.7 3.2 0.027 14.4 0.0 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family TcdB_N PF12918.7 KFP01871.1 - 4.7 7.6 14.1 2 8.8 5.3 4.0 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain Hydrolase_4 PF12146.8 KFP01872.1 - 0.00017 20.9 0.0 0.00028 20.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 GIT1_C PF12205.8 KFP01873.1 - 1.1e-47 160.9 4.9 1.4e-47 160.6 0.8 2.5 2 0 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term GIT_CC PF16559.5 KFP01873.1 - 7.7e-33 112.2 5.1 7.7e-33 112.2 5.1 2.2 2 0 0 2 2 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor GIT_SHD PF08518.11 KFP01873.1 - 1.1e-25 89.0 5.9 2.5e-13 49.4 0.5 2.8 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT ArfGap PF01412.18 KFP01873.1 - 8e-22 77.5 0.0 2.2e-21 76.1 0.0 1.8 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_2 PF12796.7 KFP01873.1 - 5.8e-09 36.4 0.0 1.7e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP01873.1 - 9.7e-08 32.1 0.0 3.7e-07 30.3 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP01873.1 - 4.7e-07 30.2 0.0 0.00064 20.2 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFP01873.1 - 0.00047 20.5 0.2 0.0048 17.3 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 KFP01873.1 - 0.014 15.9 0.0 5 8.0 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeat T7SS_ESX_EspC PF10824.8 KFP01873.1 - 0.015 15.7 4.6 0.021 15.3 0.1 3.0 3 0 0 3 3 2 0 Excreted virulence factor EspC, type VII ESX diderm YabA PF06156.13 KFP01873.1 - 0.026 15.1 0.2 0.11 13.1 0.0 2.1 2 0 0 2 2 1 0 Initiation control protein YabA ZapB PF06005.12 KFP01873.1 - 0.041 14.3 1.3 0.041 14.3 1.3 2.5 3 0 0 3 3 2 0 Cell division protein ZapB Shugoshin_N PF07558.11 KFP01873.1 - 0.044 13.6 4.0 0.13 12.2 4.0 1.8 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region WDCP PF15390.6 KFP01873.1 - 0.064 11.6 2.5 0.1 11.0 2.5 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Fib_alpha PF08702.10 KFP01873.1 - 0.091 12.9 2.3 9.3 6.4 1.5 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4147 PF13660.6 KFP01873.1 - 0.15 11.6 0.1 9.7 5.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) TTRAP PF14203.6 KFP01873.1 - 0.18 11.8 0.1 0.18 11.8 0.1 2.3 3 0 0 3 3 2 0 Putative tranposon-transfer assisting protein CRIC_ras_sig PF10534.9 KFP01873.1 - 5.9 7.1 7.7 1.2 9.4 0.1 3.5 4 0 0 4 4 4 0 Connector enhancer of kinase suppressor of ras bZIP_1 PF00170.21 KFP01873.1 - 7 6.8 8.0 0.57 10.3 2.4 2.2 2 0 0 2 2 2 0 bZIP transcription factor GPCR_chapero_1 PF11904.8 KFP01874.1 - 6.1e-102 341.2 0.0 8e-102 340.8 0.0 1.1 1 0 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.7 KFP01874.1 - 5.5e-10 39.7 0.0 1.2e-09 38.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP01874.1 - 1.7e-08 34.9 0.0 3.6e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP01874.1 - 1.2e-07 31.8 0.0 2.8e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KFP01874.1 - 1e-06 28.9 0.0 4.3e-06 26.9 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KFP01874.1 - 3.3e-06 27.0 0.0 0.00065 20.0 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat UIM PF02809.20 KFP01874.1 - 8.2 6.6 24.4 0.71 9.9 2.1 4.1 4 0 0 4 4 4 0 Ubiquitin interaction motif DUF1899 PF08953.11 KFP01875.1 - 9.6e-32 108.7 0.0 2.7e-31 107.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KFP01875.1 - 2.9e-22 78.3 0.1 5.2e-22 77.5 0.1 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KFP01875.1 - 1e-13 51.5 4.1 0.00015 22.5 0.3 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP01875.1 - 1.1e-07 32.1 0.4 0.0085 16.4 0.0 2.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DSPc PF00782.20 KFP01876.1 - 4.8e-34 117.0 0.0 1.7e-33 115.2 0.0 2.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DEK_C PF08766.11 KFP01876.1 - 5e-11 42.3 5.1 1.1e-10 41.3 5.1 1.6 1 0 0 1 1 1 1 DEK C terminal domain Y_phosphatase PF00102.27 KFP01876.1 - 0.022 14.3 0.0 0.075 12.6 0.0 1.9 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF2040 PF09745.9 KFP01877.1 - 4.2e-38 130.1 24.0 4.2e-38 130.1 24.0 5.4 3 1 2 5 5 5 1 Coiled-coil domain-containing protein 55 (DUF2040) SNF PF00209.18 KFP01878.1 - 5e-229 761.3 36.0 5.7e-229 761.1 36.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family 5HT_transport_N PF03491.13 KFP01878.1 - 2.8e-07 30.6 1.0 6e-07 29.5 1.0 1.5 1 0 0 1 1 1 1 Serotonin (5-HT) neurotransmitter transporter, N-terminus Peptidase_C1_2 PF03051.15 KFP01879.1 - 2e-204 679.4 0.5 2.2e-204 679.2 0.5 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KFP01879.1 - 5.7e-07 29.9 0.5 0.0085 16.2 0.2 2.8 3 0 0 3 3 3 2 Papain family cysteine protease Ig_3 PF13927.6 KFP01880.1 - 9.3e-22 77.4 3.8 4.2e-17 62.5 1.4 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP01880.1 - 4.3e-19 68.5 3.3 1e-12 48.0 1.3 2.2 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP01880.1 - 8.7e-18 64.2 0.7 1.7e-16 60.1 0.2 2.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP01880.1 - 2.3e-17 63.1 2.3 2.6e-13 50.1 0.6 2.1 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFP01880.1 - 2e-10 40.8 6.0 7.2e-08 32.6 2.5 3.6 2 2 1 3 3 3 1 Immunoglobulin V-set domain Ig_4 PF16680.5 KFP01880.1 - 0.00019 21.6 2.7 0.075 13.3 1.3 2.8 2 1 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFP01880.1 - 0.00023 21.5 1.2 0.014 15.8 0.7 2.4 2 1 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFP01880.1 - 0.00088 18.8 0.2 0.72 9.5 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 KFP01880.1 - 0.0012 18.9 4.0 0.006 16.6 1.3 2.7 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFP01880.1 - 0.0023 18.0 0.2 0.026 14.6 0.1 2.4 2 1 0 2 2 2 1 Izumo-like Immunoglobulin domain C1-set PF07654.15 KFP01880.1 - 0.02 15.3 1.4 0.2 12.0 0.8 2.5 3 0 0 3 3 3 0 Immunoglobulin C1-set domain V-set_CD47 PF08204.11 KFP01880.1 - 0.045 13.7 0.3 0.11 12.5 0.3 1.6 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain Peptidase_M14 PF00246.24 KFP01881.1 - 1.8e-173 576.1 0.0 4.9e-85 285.8 0.0 3.2 3 0 0 3 3 3 3 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 KFP01881.1 - 2.3e-37 127.1 2.5 1.1e-13 51.2 0.0 3.5 3 0 0 3 3 3 3 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KFP01881.1 - 3.4e-20 71.8 0.3 9.7e-08 31.9 0.0 3.4 3 0 0 3 3 3 3 CarboxypepD_reg-like domain PEGA PF08308.11 KFP01881.1 - 3.8e-08 33.1 0.1 0.023 14.6 0.0 3.7 3 0 0 3 3 3 3 PEGA domain AstE_AspA PF04952.14 KFP01881.1 - 0.00094 18.3 0.1 0.026 13.6 0.1 2.4 2 0 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF3823 PF12866.7 KFP01881.1 - 0.026 14.8 0.0 1.5 9.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3823) N-terminal domain Calycin_like PF13944.6 KFP01881.1 - 0.072 13.4 0.1 8.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Calycin-like beta-barrel domain fn3_3 PF14686.6 KFP01881.1 - 0.23 11.3 0.8 28 4.6 0.1 2.5 2 0 0 2 2 2 0 Polysaccharide lyase family 4, domain II V-SNARE_C PF12352.8 KFP01882.1 - 7.3e-22 77.4 3.6 7.3e-22 77.4 3.6 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KFP01882.1 - 0.0031 17.4 1.1 0.018 14.9 0.2 2.2 2 0 0 2 2 2 1 Sec20 Abi_C PF14355.6 KFP01882.1 - 0.1 12.7 0.1 2 8.6 0.0 2.4 2 0 0 2 2 2 0 Abortive infection C-terminus DUF1664 PF07889.12 KFP01882.1 - 0.13 12.3 1.5 0.24 11.4 0.5 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Muted PF14942.6 KFP01882.1 - 0.24 11.7 4.8 1.8 8.9 2.0 2.3 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein CD225 PF04505.12 KFP01883.1 - 8.3e-25 86.7 0.3 1.3e-24 86.1 0.3 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF4190 PF13828.6 KFP01883.1 - 6.6e-05 22.6 4.8 0.00097 18.9 3.9 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4190) DUF2852 PF11014.8 KFP01883.1 - 0.019 15.1 0.1 0.032 14.4 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2852) RhoGAP PF00620.27 KFP01884.1 - 2.7e-48 163.7 0.0 6.7e-48 162.4 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain RhoGEF PF00621.20 KFP01884.1 - 3.2e-32 112.2 2.4 7e-32 111.1 2.4 1.6 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 KFP01884.1 - 2.7e-10 40.7 4.8 2.2e-09 37.8 1.8 3.2 2 1 0 2 2 2 1 PH domain C2 PF00168.30 KFP01884.1 - 1.6e-07 31.5 0.1 4.2e-07 30.2 0.1 1.7 1 0 0 1 1 1 1 C2 domain Phage_antiter_Q PF06323.11 KFP01884.1 - 0.015 14.9 0.1 0.031 13.8 0.1 1.5 1 0 0 1 1 1 0 Phage antitermination protein Q Tim17 PF02466.19 KFP01885.1 - 1.5e-29 102.6 4.7 1.8e-29 102.4 4.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CH PF00307.31 KFP01886.1 - 8.2e-22 77.5 0.0 2.9e-21 75.7 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFP01886.1 - 3.4e-06 26.8 0.3 1.2e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 CAMSAP CH domain Fez1 PF06818.15 KFP01886.1 - 0.0056 17.1 2.1 0.0056 17.1 2.1 5.3 2 1 3 5 5 5 1 Fez1 DUF641 PF04859.12 KFP01886.1 - 0.02 15.2 0.5 0.02 15.2 0.5 6.6 4 2 3 7 7 7 0 Plant protein of unknown function (DUF641) DUF5475 PF17569.2 KFP01886.1 - 0.1 12.9 0.4 0.3 11.4 0.4 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5475) 7tm_1 PF00001.21 KFP01887.1 - 9.5e-54 182.5 15.4 1.2e-53 182.2 15.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP01887.1 - 4.2e-14 52.6 17.0 4.8e-08 32.7 4.7 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP01887.1 - 2.9e-13 50.2 16.0 4.5e-13 49.6 16.0 1.2 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP01887.1 - 9.8e-06 25.4 17.9 9.8e-06 25.4 17.9 2.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx GPR_Gpa2_C PF11970.8 KFP01887.1 - 0.0056 16.7 0.2 0.021 14.9 0.2 2.0 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term SWIM PF04434.17 KFP01888.1 - 2.4e-07 30.3 3.3 4.1e-07 29.5 3.3 1.4 1 0 0 1 1 1 1 SWIM zinc finger TPR_12 PF13424.6 KFP01889.1 - 1.9e-25 89.0 17.8 2.6e-12 46.9 0.2 4.3 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFP01889.1 - 8.2e-15 53.7 16.4 0.0073 16.3 0.2 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 KFP01889.1 - 9e-14 50.8 13.2 0.005 16.7 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP01889.1 - 3.7e-13 49.5 18.5 1.5e-07 31.1 3.8 2.2 1 1 1 2 2 2 2 MalT-like TPR region TPR_1 PF00515.28 KFP01889.1 - 8.3e-11 41.2 19.2 0.014 15.2 0.3 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFP01889.1 - 7.9e-07 28.8 17.9 0.14 12.4 0.3 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP01889.1 - 1.2e-06 28.8 16.9 0.74 10.8 0.3 6.2 2 2 4 6 6 6 2 Tetratricopeptide repeat ComR_TPR PF18710.1 KFP01889.1 - 1.2e-06 28.2 9.3 7.3e-06 25.7 3.7 2.4 2 1 0 2 2 2 1 ComR tetratricopeptide TPR_19 PF14559.6 KFP01889.1 - 3.9e-06 27.3 19.5 0.0024 18.4 0.1 4.3 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFP01889.1 - 1.2e-05 25.0 13.5 0.053 13.6 0.1 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFP01889.1 - 0.0001 22.9 13.9 0.027 15.1 0.7 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 KFP01889.1 - 0.00012 22.4 0.0 2.3 9.1 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFP01889.1 - 0.0003 21.0 12.8 1.7 9.2 0.0 6.3 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_21 PF09976.9 KFP01889.1 - 0.051 13.3 20.5 0.32 10.7 6.2 3.2 2 2 0 2 2 2 0 Tetratricopeptide repeat-like domain ANAPC5 PF12862.7 KFP01889.1 - 0.063 13.3 12.0 0.13 12.3 0.9 3.5 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 5 LsmAD PF06741.13 KFP01889.1 - 0.36 11.4 3.9 0.87 10.2 0.0 3.1 3 0 0 3 3 3 0 LsmAD domain PPR PF01535.20 KFP01889.1 - 0.48 10.8 1.8 5.7 7.4 0.2 3.3 4 0 0 4 4 3 0 PPR repeat NRBF2_MIT PF17169.4 KFP01889.1 - 1.1 9.5 7.5 0.59 10.4 1.5 3.4 1 1 3 4 4 4 0 MIT domain of nuclear receptor-binding factor 2 Usp PF00582.26 KFP01889.1 - 6.2 7.3 10.1 23 5.5 0.4 3.0 2 2 0 2 2 2 0 Universal stress protein family GPS2_interact PF15784.5 KFP01890.1 - 9.8e-36 122.1 5.0 9.8e-36 122.1 5.0 6.7 8 0 0 8 8 8 1 G-protein pathway suppressor 2-interacting domain Myb_DNA-binding PF00249.31 KFP01890.1 - 6.7e-17 61.4 0.3 2.2e-12 47.0 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFP01890.1 - 0.0025 18.0 2.3 0.066 13.5 0.3 3.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain PIG-L PF02585.17 KFP01891.1 - 4.3e-11 43.6 0.0 1.4e-10 41.9 0.0 1.6 2 0 0 2 2 2 1 GlcNAc-PI de-N-acetylase GFA PF04828.14 KFP01892.1 - 9.9e-10 38.6 1.5 9.9e-10 38.6 1.5 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme ASFV_p27 PF06556.11 KFP01892.1 - 0.047 13.8 0.2 0.067 13.3 0.2 1.2 1 0 0 1 1 1 0 IAP-like protein p27 C-terminus ubiquitin PF00240.23 KFP01893.1 - 8.1e-133 432.4 14.0 4.2e-34 116.1 0.3 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 KFP01893.1 - 7e-64 211.6 14.8 4.5e-16 58.4 0.4 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFP01893.1 - 1e-24 86.8 4.7 0.00011 22.6 0.1 5.6 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 KFP01893.1 - 1.5e-17 63.3 1.3 0.012 15.5 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KFP01893.1 - 2.7e-15 56.4 1.6 0.044 13.9 0.0 5.1 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KFP01893.1 - 2.5e-13 50.2 5.0 0.045 14.1 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain DUF2407 PF10302.9 KFP01893.1 - 3.3e-12 46.9 0.1 0.44 11.1 0.0 4.2 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 KFP01893.1 - 2.9e-06 27.2 0.1 2.2 8.1 0.0 3.8 1 1 3 4 4 4 2 Silencing defective 2 N-terminal ubiquitin domain TUG-UBL1 PF11470.8 KFP01893.1 - 3.5e-06 27.1 0.0 2.4 8.4 0.0 4.1 4 0 0 4 4 4 1 TUG ubiquitin-like domain Methyltrans_RNA PF04452.14 KFP01893.1 - 4e-06 26.3 0.2 1.9 7.8 0.0 3.2 3 0 0 3 3 3 3 RNA methyltransferase Ubiquitin_4 PF18036.1 KFP01893.1 - 8.1e-06 25.8 18.1 23 5.1 0.2 7.4 7 1 0 7 7 7 0 Ubiquitin-like domain DUF2870 PF11069.8 KFP01893.1 - 2.3e-05 24.7 0.0 28 5.2 0.0 4.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) RBD PF02196.15 KFP01893.1 - 2.5e-05 24.2 0.0 32 4.7 0.0 4.3 4 0 0 4 4 4 0 Raf-like Ras-binding domain UDP-g_GGTase PF06427.11 KFP01893.1 - 4.2e-05 23.6 1.8 5.1 7.3 0.0 3.9 4 0 0 4 4 4 2 UDP-glucose:Glycoprotein Glucosyltransferase DUF3861 PF12977.7 KFP01893.1 - 0.00014 22.0 1.2 39 4.5 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) Big_7 PF17957.1 KFP01893.1 - 0.0015 19.3 0.0 1.3e+02 3.4 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig domain DUF969 PF06149.12 KFP01893.1 - 0.004 16.6 0.0 20 4.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF969) GDYXXLXY PF14345.6 KFP01893.1 - 0.0062 16.4 0.1 1e+02 2.6 0.0 4.1 4 0 0 4 4 4 0 GDYXXLXY protein TraK PF06586.11 KFP01893.1 - 0.0083 15.8 0.2 87 2.7 0.0 3.9 4 0 0 4 4 4 0 TraK protein FlgD_ig PF13860.6 KFP01893.1 - 0.0087 15.9 5.5 54 3.7 0.1 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain CorA PF01544.18 KFP01893.1 - 0.0091 15.3 0.3 73 2.5 0.0 3.9 4 0 0 4 4 4 0 CorA-like Mg2+ transporter protein ProRS-C_2 PF09181.10 KFP01893.1 - 0.031 14.4 3.1 1.2e+02 2.9 0.0 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal ORF11CD3 PF10549.9 KFP01893.1 - 0.036 14.2 0.0 85 3.4 0.0 4.0 3 0 0 3 3 3 0 ORF11CD3 domain Phage_sheath_1N PF17481.2 KFP01893.1 - 0.042 14.3 3.6 38 4.8 0.3 3.9 1 1 1 2 2 2 0 Phage tail sheath protein beta-sandwich domain Transglut_core2 PF13369.6 KFP01893.1 - 0.056 13.0 0.1 23 4.5 0.0 3.1 3 0 0 3 3 3 0 Transglutaminase-like superfamily DUF5450 PF17529.2 KFP01893.1 - 0.065 13.4 0.0 1.1e+02 2.8 0.0 3.5 4 0 0 4 4 4 0 Family of unknown function (DUF5450) PI3K_p85B PF02192.16 KFP01893.1 - 2.4 7.9 7.1 1.5e+02 2.2 0.1 4.1 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Ank_2 PF12796.7 KFP01894.1 - 8e-21 74.4 0.6 1.8e-10 41.3 0.0 4.3 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP01894.1 - 4.2e-13 48.2 0.0 5.7e-05 23.2 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 KFP01894.1 - 2e-11 44.2 0.2 0.0022 18.6 0.1 5.0 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP01894.1 - 6.3e-11 42.3 0.1 7.8e-05 22.9 0.0 4.6 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFP01894.1 - 1.1e-10 41.5 0.2 0.0001 22.6 0.1 5.2 5 0 0 5 5 5 2 Ankyrin repeat Ion_trans PF00520.31 KFP01894.1 - 4.3e-09 36.0 21.6 7.1e-09 35.3 21.6 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KFP01894.1 - 0.053 12.2 15.2 0.12 11.0 15.2 1.6 1 1 0 1 1 1 0 Polycystin cation channel P2X_receptor PF00864.19 KFP01895.1 - 3.6e-165 549.5 0.7 4.1e-165 549.3 0.7 1.0 1 0 0 1 1 1 1 ATP P2X receptor WAP PF00095.21 KFP01895.1 - 3 8.3 6.1 0.54 10.7 1.8 2.0 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Rab5ip PF07019.12 KFP01896.1 - 3e-23 82.2 8.6 3.3e-23 82.1 8.6 1.0 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF5084 PF16894.5 KFP01896.1 - 0.025 15.0 1.3 0.033 14.6 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5084) DUF2070 PF09843.9 KFP01896.1 - 0.37 9.0 1.8 0.39 9.0 1.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PDZ PF00595.24 KFP01897.1 - 3.5e-20 72.1 0.2 4.4e-20 71.8 0.2 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP01897.1 - 1.8e-11 44.2 0.3 2.5e-11 43.7 0.3 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP01897.1 - 3.9e-11 42.6 0.1 7.2e-11 41.8 0.1 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KFP01897.1 - 0.13 12.6 0.1 0.23 11.8 0.0 1.4 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain PQ-loop PF04193.14 KFP01898.1 - 6.7e-25 86.6 9.6 2.4e-19 68.9 3.7 2.6 2 0 0 2 2 2 2 PQ loop repeat DUF4929 PF16283.5 KFP01898.1 - 0.012 14.6 0.2 0.018 14.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4929) Blt1 PF12754.7 KFP01898.1 - 0.076 13.3 0.3 0.12 12.7 0.3 1.2 1 0 0 1 1 1 0 Blt1 N-terminal domain FGGY_N PF00370.21 KFP01899.1 - 7.2e-25 88.0 0.0 1e-23 84.2 0.0 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KFP01899.1 - 0.0074 15.8 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family GBP_PSP PF02425.15 KFP01899.1 - 0.16 11.6 2.2 0.63 9.7 0.2 2.5 2 0 0 2 2 2 0 Paralytic/GBP/PSP peptide Ank_2 PF12796.7 KFP01900.1 - 1.4e-15 57.7 1.6 1.8e-08 34.8 0.2 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ion_trans PF00520.31 KFP01900.1 - 1.6e-13 50.5 19.5 2.5e-13 49.8 19.5 1.3 1 0 0 1 1 1 1 Ion transport protein Ank_3 PF13606.6 KFP01900.1 - 2.1e-11 43.0 0.1 6.2e-05 23.1 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KFP01900.1 - 9.9e-11 41.6 0.3 5.2e-05 23.5 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KFP01900.1 - 5.8e-10 39.2 0.4 0.0016 18.7 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP01900.1 - 2.7e-08 34.2 0.0 6.7e-05 23.4 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) DUF3562 PF12085.8 KFP01900.1 - 0.052 13.2 0.0 5 6.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3562) Ank_2 PF12796.7 KFP01901.1 - 1.8e-20 73.3 1.8 5.2e-09 36.6 0.3 3.7 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP01901.1 - 8.1e-13 47.3 0.1 0.0059 17.0 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KFP01901.1 - 5.9e-12 45.5 0.1 0.029 14.8 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KFP01901.1 - 1.1e-10 41.5 0.1 0.073 13.4 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP01901.1 - 2.1e-09 37.7 0.1 0.009 16.6 0.0 4.9 3 1 1 5 5 5 3 Ankyrin repeats (many copies) Ion_trans PF00520.31 KFP01901.1 - 3.4e-09 36.3 19.9 6.1e-09 35.5 19.9 1.4 1 0 0 1 1 1 1 Ion transport protein DUF2070 PF09843.9 KFP01901.1 - 4.3 5.5 16.7 6.3 5.0 16.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) AstE_AspA PF04952.14 KFP01902.1 - 1.4e-60 204.8 0.0 1.6e-60 204.7 0.0 1.0 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family UPF0258 PF06789.12 KFP01903.1 - 0.074 13.2 1.8 0.14 12.2 1.8 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) L_HMGIC_fpl PF10242.9 KFP01904.1 - 4.6e-14 53.0 0.5 5.7e-14 52.7 0.5 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein DUF1240 PF06836.12 KFP01904.1 - 0.069 13.7 0.2 0.086 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) Claudin_2 PF13903.6 KFP01904.1 - 0.088 12.6 0.4 0.097 12.4 0.4 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction RGS PF00615.19 KFP01905.1 - 3.8e-31 107.8 2.0 2.9e-12 46.9 0.1 3.4 3 0 0 3 3 3 3 Regulator of G protein signaling domain TetR_C_8 PF14278.6 KFP01905.1 - 2.7 8.1 4.6 1.4 9.1 0.4 2.5 2 1 0 2 2 2 0 Transcriptional regulator C-terminal region WD40 PF00400.32 KFP01906.1 - 1.9e-46 155.1 18.9 2.6e-09 37.6 0.1 7.1 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP01906.1 - 2.6e-18 66.1 0.9 8e-06 26.1 0.1 4.7 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 KFP01906.1 - 5e-13 49.4 0.1 1.1e-12 48.3 0.1 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 KFP01906.1 - 2.3e-06 26.8 0.1 0.055 12.4 0.0 4.0 3 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFP01906.1 - 0.00049 20.0 0.0 1.7 8.5 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KFP01906.1 - 0.00074 19.4 0.4 0.26 11.3 0.1 3.6 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KFP01906.1 - 0.0014 17.4 0.5 8.6 4.9 0.3 3.9 3 1 1 4 4 4 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KFP01906.1 - 0.0018 17.3 2.1 0.11 11.4 0.2 2.5 2 0 0 2 2 2 2 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 KFP01906.1 - 0.0046 15.3 0.0 0.043 12.1 0.0 2.2 2 1 1 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz nos_propeller PF18764.1 KFP01906.1 - 0.18 11.7 0.1 13 5.7 0.0 3.3 3 1 1 4 4 4 0 Nitrous oxide reductase propeller repeat Lipase_GDSL_2 PF13472.6 KFP01907.1 - 0.00085 19.8 0.0 0.0026 18.2 0.0 1.7 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 KFP01907.1 - 0.0015 17.8 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 OSK domain GDPD PF03009.17 KFP01908.1 - 3.9e-20 72.7 0.0 5.1e-17 62.5 0.0 2.2 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KFP01908.1 - 0.11 13.0 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Leader_Thr PF08254.11 KFP01908.1 - 0.48 10.2 2.0 1.1 9.1 2.0 1.6 1 0 0 1 1 1 0 Threonine leader peptide DUF4131 PF13567.6 KFP01908.1 - 1.6 8.4 7.3 0.75 9.4 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) TMEM190 PF15431.6 KFP01908.1 - 6.3 6.9 7.2 1.1 9.4 2.6 2.0 2 0 0 2 2 2 0 Transmembrane protein 190 Kelch_1 PF01344.25 KFP01911.1 - 2.8e-43 145.3 12.6 9.1e-12 44.4 0.0 7.7 6 2 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFP01911.1 - 4.4e-34 115.6 7.8 4.1e-08 33.2 0.1 6.4 4 1 2 6 6 6 5 Kelch motif BACK PF07707.15 KFP01911.1 - 2.2e-33 114.4 0.4 6.2e-33 113.0 0.2 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 KFP01911.1 - 2.6e-29 101.7 0.0 1.1e-28 99.6 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 KFP01911.1 - 6.9e-28 95.5 7.4 0.00011 22.0 0.0 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KFP01911.1 - 2.8e-19 68.8 8.3 0.003 17.5 0.0 6.6 5 2 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP01911.1 - 6.2e-16 58.2 3.6 0.00028 21.1 0.1 6.4 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP01911.1 - 1.2e-14 53.9 9.0 0.034 14.2 0.0 6.2 6 0 0 6 6 6 4 Kelch motif DUF3342 PF11822.8 KFP01911.1 - 4.1e-05 23.7 0.0 0.00046 20.3 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) STOP PF05217.12 KFP01912.1 - 1 9.7 5.2 1.1 9.6 0.8 2.8 3 0 0 3 3 3 0 STOP protein DAGAT PF03982.13 KFP01913.1 - 4.6e-117 390.2 0.0 5.4e-117 389.9 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 KFP01913.1 - 0.057 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Acyltransferase DAGAT PF03982.13 KFP01914.1 - 2.1e-142 473.3 0.0 2.6e-142 473.1 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 KFP01914.1 - 0.0055 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase wnt PF00110.19 KFP01916.1 - 1.2e-107 360.1 16.0 1.4e-107 359.9 16.0 1.0 1 0 0 1 1 1 1 wnt family THAP PF05485.12 KFP01917.1 - 3e-17 63.3 3.7 1.1e-16 61.6 3.7 2.0 1 0 0 1 1 1 1 THAP domain DUF4371 PF14291.6 KFP01917.1 - 1.7e-12 47.5 0.0 3.6e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFP01917.1 - 3.4e-10 39.6 0.1 1e-09 38.1 0.1 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region L27 PF02828.16 KFP01917.1 - 0.022 14.5 0.1 4.5 7.1 0.1 2.6 2 0 0 2 2 2 0 L27 domain Guanylate_cyc PF00211.20 KFP01918.1 - 1.9e-65 220.0 0.0 4.8e-65 218.6 0.0 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 KFP01918.1 - 2.3e-64 217.7 0.0 3.3e-64 217.2 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 KFP01918.1 - 5e-35 121.0 0.0 7.9e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP01918.1 - 4.5e-26 91.8 0.0 9e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 KFP01918.1 - 3.4e-06 26.6 2.3 5.6e-06 25.9 2.3 1.3 1 0 0 1 1 1 1 Heme NO binding associated Kinase-like PF14531.6 KFP01918.1 - 0.076 12.3 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Catalase_C PF18011.1 KFP01918.1 - 0.085 12.5 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 C-terminal domain found in long catalases LRR_8 PF13855.6 KFP01919.1 - 9.4e-37 124.6 26.5 1e-12 47.6 2.9 6.4 3 2 3 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 KFP01919.1 - 1.3e-21 76.3 30.5 0.00013 22.2 1.7 7.2 3 2 6 9 9 9 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP01919.1 - 2.1e-12 47.1 0.0 1.7e-06 28.0 0.2 2.4 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFP01919.1 - 3.7e-11 42.0 24.5 0.031 14.8 0.3 9.8 8 1 1 9 9 9 3 Leucine Rich Repeat LRR_6 PF13516.6 KFP01919.1 - 3.4e-05 23.6 26.6 0.75 10.0 0.0 8.7 10 0 0 10 10 10 3 Leucine Rich repeat LRR_9 PF14580.6 KFP01919.1 - 0.0029 17.1 5.9 1.3 8.5 1.0 3.2 1 1 1 3 3 3 2 Leucine-rich repeat LRRNT PF01462.18 KFP01919.1 - 0.12 12.0 1.7 0.45 10.2 0.5 2.5 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain RVT_1 PF00078.27 KFP01921.1 - 0.041 13.4 0.0 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ceramidase PF05875.12 KFP01923.1 - 6.8e-76 255.2 14.4 8.3e-76 254.9 14.4 1.0 1 0 0 1 1 1 1 Ceramidase HMw1_D2 PF18254.1 KFP01923.1 - 0.14 12.6 0.4 3 8.3 0.0 2.2 2 0 0 2 2 2 0 HMW1 domain 2 DUF2070 PF09843.9 KFP01923.1 - 1.2 7.4 4.5 1.5 7.0 4.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Peptidase_C2 PF00648.21 KFP01924.1 - 1.4e-123 411.7 1.5 2e-123 411.2 1.5 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KFP01924.1 - 1.2e-37 129.3 0.0 2.1e-37 128.5 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III C2 PF00168.30 KFP01924.1 - 1.2e-12 48.0 0.0 3.2e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain Myosin_head PF00063.21 KFP01925.1 - 2e-245 816.2 3.7 2.7e-245 815.8 3.7 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.17 KFP01925.1 - 9.7e-64 212.6 0.2 4e-32 110.9 0.0 3.3 3 0 0 3 3 2 2 MyTH4 domain FERM_M PF00373.18 KFP01925.1 - 1.2e-27 96.7 7.1 2e-18 66.9 0.0 4.5 5 0 0 5 5 4 2 FERM central domain IQ PF00612.27 KFP01925.1 - 8.1e-18 62.5 10.4 0.00033 20.2 0.1 5.0 4 0 0 4 4 4 4 IQ calmodulin-binding motif FERM_N PF09379.10 KFP01925.1 - 7e-09 35.5 0.2 0.0036 17.2 0.1 2.7 2 0 0 2 2 2 2 FERM N-terminal domain SH3_9 PF14604.6 KFP01925.1 - 0.026 14.4 0.0 0.13 12.1 0.0 2.3 1 0 0 1 1 1 0 Variant SH3 domain Borrelia_P83 PF05262.11 KFP01925.1 - 0.029 12.9 1.2 0.047 12.2 1.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein PID PF00640.23 KFP01925.1 - 0.038 14.0 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) AAA_22 PF13401.6 KFP01925.1 - 0.051 13.8 3.8 0.18 12.1 0.0 3.6 3 1 1 4 4 4 0 AAA domain AAA_16 PF13191.6 KFP01925.1 - 0.059 13.8 0.4 0.37 11.1 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain SH3_1 PF00018.28 KFP01925.1 - 0.069 12.8 1.8 0.73 9.5 0.1 3.1 3 0 0 3 3 3 0 SH3 domain SH3_2 PF07653.17 KFP01925.1 - 0.1 12.3 0.7 0.54 10.0 0.0 2.6 2 0 0 2 2 2 0 Variant SH3 domain DUF3752 PF12572.8 KFP01925.1 - 0.24 11.9 8.5 0.58 10.7 8.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) ABC_tran PF00005.27 KFP01925.1 - 0.29 11.6 2.4 0.33 11.4 0.0 2.2 2 0 0 2 2 2 0 ABC transporter DUF4407 PF14362.6 KFP01925.1 - 5 6.4 7.2 8.9 5.6 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GDPD PF03009.17 KFP01926.1 - 1.4e-17 64.2 0.0 1.8e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CENP-T_C PF15511.6 KFP01926.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Pkinase PF00069.25 KFP01927.1 - 7.5e-73 245.1 0.0 1.3e-72 244.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP01927.1 - 3.7e-47 160.8 0.0 6e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KFP01927.1 - 3.5e-25 88.1 0.0 1.1e-24 86.5 0.0 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KFP01927.1 - 1.5e-07 31.1 0.0 0.00024 20.5 0.0 2.4 1 1 1 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KFP01927.1 - 1.6e-06 27.1 0.0 4.6e-06 25.7 0.0 1.6 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFP01927.1 - 0.0058 16.6 0.0 0.12 12.2 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family DSHCT PF08148.12 KFP01927.1 - 0.013 15.1 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 DSHCT (NUC185) domain Kdo PF06293.14 KFP01927.1 - 0.039 13.3 0.0 0.097 12.0 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MIP PF00230.20 KFP01928.1 - 5.7e-09 36.0 4.8 5.7e-09 36.0 4.8 1.7 1 1 0 2 2 2 1 Major intrinsic protein SLATT_5 PF18160.1 KFP01928.1 - 0.14 11.4 0.4 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Voldacs PF03517.13 KFP01929.1 - 3.8e-29 101.6 1.1 4.9e-29 101.2 1.1 1.1 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling WHIM1 PF15612.6 KFP01930.1 - 1e-11 44.1 0.1 2.4e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 PHD PF00628.29 KFP01930.1 - 2e-10 40.4 4.3 7.3e-10 38.6 4.3 2.1 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 KFP01930.1 - 0.27 11.2 2.5 0.92 9.5 2.5 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Polyoma_lg_T_C PF06431.11 KFP01930.1 - 8.5 5.1 12.4 1.7 7.5 1.9 2.8 2 0 0 2 2 2 0 Polyomavirus large T antigen C-terminus DUF498 PF04430.14 KFP01931.1 - 1.6e-19 70.0 0.0 1.8e-19 69.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Indigoidine_A PF04227.12 KFP01931.1 - 0.011 15.2 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 Indigoidine synthase A like protein HflK_N PF12221.8 KFP01931.1 - 0.065 13.2 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial membrane protein N terminal HEAT PF02985.22 KFP01932.1 - 9e-21 72.2 6.9 0.021 15.1 0.0 8.7 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.6 KFP01932.1 - 1.1e-15 57.8 5.5 1.2e-05 25.6 0.1 5.1 4 1 1 6 6 6 3 HEAT repeats Adaptin_N PF01602.20 KFP01932.1 - 3e-10 39.3 4.4 0.00026 19.7 0.1 3.2 2 1 1 3 3 3 3 Adaptin N terminal region Cnd1 PF12717.7 KFP01932.1 - 6.5e-10 39.3 4.6 0.0022 18.1 0.5 4.3 2 1 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KFP01932.1 - 2.2e-08 34.6 1.0 0.00023 21.7 0.1 4.5 4 2 1 5 5 4 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KFP01932.1 - 3.6e-06 26.7 0.4 4.1 6.9 0.1 4.7 2 2 3 5 5 5 4 CLASP N terminal Cohesin_HEAT PF12765.7 KFP01932.1 - 0.00017 21.8 0.5 0.19 12.1 0.0 4.4 5 0 0 5 5 5 1 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.7 KFP01932.1 - 0.00053 19.3 3.0 0.094 11.9 0.1 2.8 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 KFP01932.1 - 0.0019 18.4 3.9 0.73 10.0 0.1 4.6 2 1 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF445 PF04286.12 KFP01932.1 - 0.0042 17.0 1.1 0.36 10.6 0.1 2.7 1 1 0 2 2 2 1 Protein of unknown function (DUF445) HEAT_PBS PF03130.16 KFP01932.1 - 0.12 13.1 0.6 41 5.3 0.0 4.7 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat MMS19_N PF14500.6 KFP01932.1 - 0.44 10.1 5.2 5.9 6.4 0.0 4.0 3 2 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II BTB_2 PF02214.22 KFP01933.1 - 2.2e-18 66.4 0.0 3.6e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Spot_14 PF07084.12 KFP01934.1 - 4.8e-24 85.2 0.2 7e-24 84.7 0.2 1.2 1 0 0 1 1 1 1 Thyroid hormone-inducible hepatic protein Spot 14 Spot_14 PF07084.12 KFP01935.1 - 1.9e-26 93.1 0.1 2.2e-26 92.8 0.1 1.0 1 0 0 1 1 1 1 Thyroid hormone-inducible hepatic protein Spot 14 ATP-synt_D PF01813.17 KFP01935.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 ATP synthase subunit D NDUF_C2 PF06374.11 KFP01936.1 - 9.9e-26 90.0 0.1 1.1e-25 89.9 0.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Alg6_Alg8 PF03155.15 KFP01937.1 - 7.5e-169 562.7 30.0 8.6e-169 562.6 30.0 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family BTB_2 PF02214.22 KFP01938.1 - 3e-21 75.6 0.0 6.2e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KFP01938.1 - 7.7e-05 22.8 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain PH PF00169.29 KFP01939.1 - 3.3e-19 69.3 0.4 1.9e-18 66.9 0.2 2.5 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 KFP01939.1 - 0.00015 22.2 3.9 0.0003 21.2 1.2 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 KFP01939.1 - 0.016 15.1 0.4 0.16 11.8 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain PH_2 PF08458.10 KFP01939.1 - 0.028 14.8 0.0 0.066 13.6 0.0 1.5 1 0 0 1 1 1 0 Plant pleckstrin homology-like region PH_3 PF14593.6 KFP01939.1 - 0.18 11.9 0.3 0.58 10.3 0.3 1.8 1 1 0 1 1 1 0 PH domain tRNA-synt_2 PF00152.20 KFP01940.1 - 1.1e-98 330.2 0.0 1.3e-98 330.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFP01940.1 - 6.5e-10 38.9 0.0 1.1e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KFP01940.1 - 0.0014 18.2 1.4 1.1 8.7 0.6 2.7 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 KFP01940.1 - 0.12 12.3 0.1 0.47 10.4 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) Ten_N PF06484.12 KFP01941.1 - 2.7e-31 109.8 12.4 3.8e-31 109.3 12.4 1.2 1 0 0 1 1 1 1 Teneurin Intracellular Region Tox-GHH PF15636.6 KFP01941.1 - 1.2e-30 105.3 0.7 2.3e-30 104.4 0.7 1.5 1 0 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin EGF_2 PF07974.13 KFP01941.1 - 3.9e-20 71.9 158.4 0.00032 21.0 13.7 9.6 9 0 0 9 9 9 8 EGF-like domain RHS_repeat PF05593.14 KFP01941.1 - 3.8e-13 49.6 27.3 0.0048 17.4 0.0 9.5 9 1 2 11 11 11 5 RHS Repeat NHL PF01436.21 KFP01941.1 - 3.9e-07 29.8 5.4 0.015 15.3 0.0 6.0 6 0 0 6 6 6 2 NHL repeat CarboxypepD_reg PF13620.6 KFP01941.1 - 0.03 14.6 1.5 0.067 13.5 0.0 2.4 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain NAGLU_N PF12971.7 KFP01941.1 - 0.033 14.0 0.1 1.6 8.6 0.0 3.2 2 0 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain hEGF PF12661.7 KFP01941.1 - 3.8 8.3 119.6 0.027 15.1 7.3 9.7 9 0 0 9 9 9 0 Human growth factor-like EGF Ten_N PF06484.12 KFP01942.1 - 1e-31 111.2 6.9 1.1e-31 111.0 6.9 1.0 1 0 0 1 1 1 1 Teneurin Intracellular Region DUF1203 PF06718.11 KFP01942.1 - 0.056 13.7 0.1 0.069 13.4 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1203) Yae1_N PF09811.9 KFP01944.1 - 3e-13 49.2 49.6 2.9e+02 1.3 0.1 5.3 1 1 1 2 2 2 0 Essential protein Yae1, N terminal HEAT_2 PF13646.6 KFP01945.1 - 2.1e-05 24.8 0.9 0.0091 16.4 0.1 1.9 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 KFP01945.1 - 0.022 15.0 0.4 0.78 10.2 0.0 3.1 4 0 0 4 4 4 0 HEAT repeat SH2 PF00017.24 KFP01946.1 - 2.6e-17 62.7 0.0 4e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 SH2 domain Nucleos_tra2_C PF07662.13 KFP01947.1 - 6.9e-77 258.0 7.2 6.9e-77 258.0 7.2 2.0 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KFP01947.1 - 1e-21 77.3 5.1 1e-21 77.3 5.1 3.6 4 1 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 KFP01947.1 - 4.3e-09 36.6 7.5 4.3e-09 36.6 7.5 3.8 3 3 0 3 3 3 1 Nucleoside recognition Alpha_kinase PF02816.18 KFP01948.1 - 8.6e-26 91.2 0.1 9.8e-26 91.0 0.1 1.0 1 0 0 1 1 1 1 Alpha-kinase family Peptidase_C14 PF00656.22 KFP01949.1 - 1.4e-20 74.4 0.1 4.7e-20 72.6 0.1 1.8 1 1 0 1 1 1 1 Caspase domain Peptidase_S24 PF00717.23 KFP01950.1 - 1.4e-09 37.8 0.1 2.3e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like Bombesin PF02044.17 KFP01951.1 - 0.025 14.6 3.5 0.041 14.0 3.5 1.4 1 0 0 1 1 1 0 Bombesin-like peptide DuoxA PF10204.9 KFP01952.1 - 4.5e-106 353.9 7.3 5e-106 353.8 7.3 1.0 1 0 0 1 1 1 1 Dual oxidase maturation factor Claudin_2 PF13903.6 KFP01952.1 - 0.09 12.5 14.5 0.48 10.2 5.9 2.4 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction BRI3BP PF14965.6 KFP01952.1 - 1.6 8.2 13.9 0.21 11.1 3.7 2.3 2 0 0 2 2 2 0 Negative regulator of p53/TP53 DUF4191 PF13829.6 KFP01952.1 - 2.5 7.4 10.9 3.7 6.8 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DuoxA PF10204.9 KFP01953.1 - 4.1e-112 373.7 11.1 4.7e-112 373.5 11.1 1.0 1 0 0 1 1 1 1 Dual oxidase maturation factor TMEM40 PF15817.5 KFP01953.1 - 3.6 7.4 5.8 8.7 6.1 0.2 2.6 2 1 0 2 2 2 0 Transmembrane protein 40 family An_peroxidase PF03098.15 KFP01954.1 - 1.3e-133 446.4 0.0 1.7e-133 446.0 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase NAD_binding_6 PF08030.12 KFP01954.1 - 3.6e-31 108.4 0.1 1.2e-30 106.7 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KFP01954.1 - 1.7e-19 70.1 16.8 4.8e-19 68.7 16.8 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFP01954.1 - 3e-18 65.9 0.0 2.7e-16 59.6 0.0 2.7 2 0 0 2 2 2 1 FAD-binding domain EF-hand_1 PF00036.32 KFP01954.1 - 2.8e-14 51.5 6.2 1.1e-06 27.8 0.8 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFP01954.1 - 4.2e-12 46.3 6.8 9.6e-08 32.4 2.5 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFP01954.1 - 1.2e-09 37.8 7.7 2.5e-05 24.0 0.2 3.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP01954.1 - 1.5e-09 37.0 5.9 0.00062 19.5 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KFP01954.1 - 6.2e-08 31.8 3.6 0.0036 16.7 0.5 2.9 2 0 0 2 2 2 2 EF hand NAD_binding_1 PF00175.21 KFP01954.1 - 0.00021 21.9 0.4 0.07 13.8 0.0 3.4 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain PufQ PF05398.11 KFP01954.1 - 0.044 13.9 1.0 0.1 12.8 0.1 2.1 2 0 0 2 2 2 0 PufQ cytochrome subunit ADH_zinc_N PF00107.26 KFP01955.1 - 1.1e-21 77.1 0.3 2.2e-21 76.2 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFP01955.1 - 6.3e-10 38.9 1.8 3.3e-09 36.5 1.8 1.9 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KFP01955.1 - 3.2e-05 23.3 1.1 4.8e-05 22.8 1.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KFP01955.1 - 0.035 15.1 0.0 0.076 14.1 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N PF08240.12 KFP01955.1 - 0.05 13.5 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Glyco_trans_1_4 PF13692.6 KFP01955.1 - 0.059 13.8 0.8 0.12 12.9 0.4 1.6 2 0 0 2 2 2 0 Glycosyl transferases group 1 DUF281 PF03436.13 KFP01955.1 - 0.072 13.5 0.2 0.2 12.1 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF281) DUF2249 PF10006.9 KFP01955.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) RRM_1 PF00076.22 KFP01956.1 - 5.9e-12 45.2 0.0 9.3e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP01956.1 - 0.17 12.0 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif PHM7_cyt PF14703.6 KFP01956.1 - 0.17 12.1 0.1 1.1 9.5 0.0 2.0 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter zf-C2H2 PF00096.26 KFP01957.1 - 1.2e-49 164.1 78.0 5.3e-07 29.8 1.4 10.5 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP01957.1 - 2.2e-33 113.2 70.4 2.9e-08 33.8 1.2 11.7 12 0 0 12 12 11 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP01957.1 - 8.7e-33 110.2 73.0 0.00084 20.0 0.6 10.6 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFP01957.1 - 1.7e-13 50.2 64.4 9e-05 22.4 0.2 10.1 10 0 0 10 10 10 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP01957.1 - 3.1e-11 43.2 56.7 0.0028 17.9 0.8 10.9 11 0 0 11 11 11 6 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFP01957.1 - 2.1e-06 27.4 61.8 4.4e-05 23.1 2.4 9.1 9 1 0 9 9 8 5 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 KFP01957.1 - 0.00056 20.2 39.1 0.16 12.3 8.2 5.8 2 1 3 5 5 5 3 C2H2-type zinc ribbon zf-BED PF02892.15 KFP01957.1 - 0.00065 19.7 0.5 0.00065 19.7 0.5 7.7 3 3 5 8 8 8 3 BED zinc finger GAGA PF09237.11 KFP01957.1 - 0.0075 16.1 19.2 2.5 8.0 0.2 5.7 3 1 2 5 5 5 3 GAGA factor Zn-ribbon_8 PF09723.10 KFP01957.1 - 0.0082 16.2 1.6 0.0082 16.2 1.6 7.9 7 2 1 8 8 8 2 Zinc ribbon domain zf-C2H2_11 PF16622.5 KFP01957.1 - 0.02 14.7 57.4 0.051 13.3 0.8 8.5 10 0 0 10 10 9 0 zinc-finger C2H2-type zf-met PF12874.7 KFP01957.1 - 0.039 14.3 48.2 0.37 11.2 0.2 9.6 9 0 0 9 9 9 0 Zinc-finger of C2H2 type PyrI_C PF02748.15 KFP01957.1 - 0.23 11.4 27.9 0.35 10.8 0.0 6.9 6 1 1 7 7 7 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zinc_ribbon_15 PF17032.5 KFP01957.1 - 2.6 8.8 44.5 0.24 12.2 0.6 6.6 2 2 7 9 9 9 0 zinc-ribbon family BolA PF01722.18 KFP01957.1 - 9.2 6.6 13.4 22 5.4 0.0 5.7 5 3 2 7 7 5 0 BolA-like protein BAH PF01426.18 KFP01958.1 - 1.3e-41 141.3 0.0 3.9e-22 78.4 0.0 2.4 2 0 0 2 2 2 2 BAH domain zf-CXXC PF02008.20 KFP01958.1 - 3.7e-15 55.7 21.5 1.1e-14 54.2 21.5 1.8 1 0 0 1 1 1 1 CXXC zinc finger domain DNMT1-RFD PF12047.8 KFP01958.1 - 8.3e-05 22.7 0.2 0.00036 20.6 0.0 2.2 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain KH_1 PF00013.29 KFP01959.1 - 4.9e-33 112.8 5.9 9.8e-17 60.6 0.8 3.1 3 0 0 3 3 3 2 KH domain KH_2 PF07650.17 KFP01959.1 - 4.9e-08 32.7 3.6 3e-05 23.8 0.2 2.4 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 KFP01959.1 - 1.4e-06 28.0 2.5 0.0082 16.0 0.0 2.8 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 KFP01959.1 - 0.096 12.8 2.0 1.3 9.2 0.1 2.4 2 0 0 2 2 2 0 NusA-like KH domain RVT_1 PF00078.27 KFP01960.1 - 0.11 12.0 0.0 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Sec3-PIP2_bind PF15277.6 KFP01961.1 - 4e-24 84.6 0.1 6.4e-24 83.9 0.1 1.3 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Synaptobrevin PF00957.21 KFP01961.1 - 6.9e-06 25.8 0.5 6.9e-06 25.8 0.5 1.8 2 0 0 2 2 2 1 Synaptobrevin DSX_dimer PF08828.10 KFP01961.1 - 0.21 11.3 0.2 5.1 6.9 0.1 2.3 2 0 0 2 2 2 0 Doublesex dimerisation domain Actin PF00022.19 KFP01962.1 - 3.7e-148 493.5 0.0 1.2e-147 491.8 0.0 1.7 1 1 0 1 1 1 1 Actin Aquarius_N PF16399.5 KFP01963.1 - 0 1073.3 0.7 0 1073.0 0.7 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 KFP01963.1 - 6.4e-26 91.2 0.1 1.5e-24 86.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KFP01963.1 - 1.1e-24 87.7 0.0 1.3e-23 84.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KFP01963.1 - 1.8e-06 28.3 0.0 2.2e-05 24.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 KFP01963.1 - 7.4e-06 26.1 0.0 2e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.17 KFP01963.1 - 0.0023 17.1 0.0 0.0042 16.2 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 KFP01963.1 - 0.0023 17.7 0.0 0.96 9.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.6 KFP01963.1 - 0.0031 17.3 0.2 0.0081 16.0 0.2 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 KFP01963.1 - 0.013 14.8 0.1 0.22 10.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 KFP01963.1 - 0.015 15.7 0.0 0.037 14.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 KFP01963.1 - 0.025 14.1 0.1 0.25 10.8 0.0 2.4 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_7 PF12775.7 KFP01963.1 - 0.061 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF4088 PF13317.6 KFP01963.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) DUF755 PF05501.11 KFP01963.1 - 0.38 11.0 1.7 0.86 9.9 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Diphthami_syn_2 PF01902.17 KFP01964.1 - 9.8e-43 146.2 0.0 1.9e-42 145.2 0.0 1.4 1 1 0 1 1 1 1 Diphthamide synthase TPD PF14811.6 KFP01965.1 - 2.9e-55 185.9 0.3 5.7e-55 184.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function TPD sequence-motif Sec34 PF04136.15 KFP01965.1 - 0.024 14.5 0.4 0.037 13.9 0.4 1.3 1 0 0 1 1 1 0 Sec34-like family PRP9_N PF16958.5 KFP01965.1 - 0.13 12.2 2.9 0.23 11.5 2.9 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor PRP9 N-terminus Meis_PKNOX_N PF16493.5 KFP01966.1 - 4.2e-35 120.0 0.8 1e-34 118.7 0.8 1.6 1 1 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 Homeobox_KN PF05920.11 KFP01966.1 - 1.1e-20 73.2 1.0 2e-20 72.4 1.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFP01966.1 - 2e-08 33.9 0.4 4e-08 33.0 0.4 1.5 1 0 0 1 1 1 1 Homeodomain Oxidored_q3 PF00499.20 KFP01967.1 - 1.4e-11 44.3 3.0 1.4e-11 44.3 3.0 1.5 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF2065 PF09838.9 KFP01967.1 - 0.23 11.5 8.0 1.3 9.1 8.0 2.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) Yae1_N PF09811.9 KFP01968.1 - 7.8e-16 57.5 49.2 0.0011 18.6 8.7 5.4 1 1 2 3 3 3 3 Essential protein Yae1, N terminal DUF2465 PF10239.9 KFP01969.1 - 2.5e-130 434.4 0.7 2.9e-130 434.2 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) DotA PF11388.8 KFP01969.1 - 0.16 12.2 0.1 0.73 10.1 0.0 2.0 2 0 0 2 2 2 0 Phagosome trafficking protein DotA RasGEF PF00617.19 KFP01970.1 - 4.5e-45 154.0 1.2 6.1e-45 153.6 0.2 1.7 2 0 0 2 2 2 1 RasGEF domain C1_1 PF00130.22 KFP01970.1 - 9.2e-15 54.3 7.8 2e-14 53.2 7.8 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RasGEF_N PF00618.20 KFP01970.1 - 2.3e-07 31.0 3.2 2.6e-07 30.8 0.9 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif EF-hand_7 PF13499.6 KFP01970.1 - 9.9e-07 29.1 3.5 0.00093 19.6 0.4 3.5 3 2 2 5 5 5 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP01970.1 - 8.7e-06 25.3 0.1 5.4e-05 22.8 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KFP01970.1 - 2.8e-05 23.3 3.0 3.9e-05 22.9 0.2 2.9 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 KFP01970.1 - 0.00012 21.4 2.4 0.00032 20.0 0.1 2.8 3 0 0 3 3 3 1 EF hand ACDC PF14733.6 KFP01970.1 - 0.0018 18.6 1.3 0.0051 17.1 0.3 2.3 2 0 0 2 2 2 1 AP2-coincident C-terminal EF-hand_8 PF13833.6 KFP01970.1 - 0.01 15.7 0.2 0.051 13.4 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain pair UvrD_C PF13361.6 KFP01970.1 - 0.023 14.1 0.9 0.078 12.3 0.4 1.9 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Borrelia_orfX PF04160.12 KFP01970.1 - 0.26 11.3 2.0 0.58 10.2 0.5 2.0 2 0 0 2 2 2 0 Orf-X protein RhoGAP PF00620.27 KFP01971.1 - 4.5e-31 107.7 0.2 9e-31 106.8 0.2 1.5 1 0 0 1 1 1 1 RhoGAP domain WIF PF02019.18 KFP01971.1 - 0.14 11.8 1.2 0.66 9.7 0.4 2.4 2 0 0 2 2 2 0 WIF domain DAN PF03045.15 KFP01972.1 - 1.6e-42 144.1 10.6 2.3e-42 143.6 10.6 1.2 1 0 0 1 1 1 1 DAN domain zf-C2HCIx2C PF10782.9 KFP01972.1 - 1.8 8.5 8.5 3.2 7.7 2.3 2.4 1 1 1 2 2 2 0 Zinc-finger FH2 PF02181.23 KFP01973.1 - 7.7e-97 324.7 6.9 1.5e-96 323.8 6.9 1.5 1 0 0 1 1 1 1 Formin Homology 2 Domain SpoIIID PF12116.8 KFP01974.1 - 0.069 13.2 0.0 0.087 12.9 0.0 1.2 1 0 0 1 1 1 0 Stage III sporulation protein D Adhesin_P1_N PF18652.1 KFP01974.1 - 0.13 12.3 0.4 0.18 11.9 0.4 1.1 1 0 0 1 1 1 0 Adhesin P1 N-terminal domain GP63 PF17471.2 KFP01975.1 - 0.0056 16.8 0.2 0.016 15.4 0.2 1.7 1 0 0 1 1 1 1 Gene product 63 ARL2_Bind_BART PF11527.8 KFP01976.1 - 2.5e-32 111.4 6.7 3e-32 111.1 6.7 1.1 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART MARVEL PF01284.23 KFP01977.1 - 4e-21 75.6 22.4 4.7e-21 75.3 22.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain Claudin_3 PF06653.11 KFP01977.1 - 0.0089 16.0 8.9 0.013 15.4 8.9 1.3 1 0 0 1 1 1 1 Tight junction protein, Claudin-like CLTH PF10607.9 KFP01980.1 - 3.6e-43 147.0 0.1 5.2e-43 146.5 0.1 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 KFP01980.1 - 4.6e-26 91.3 0.2 4.6e-26 91.3 0.2 2.0 2 0 0 2 2 2 1 SPRY domain LisH PF08513.11 KFP01980.1 - 8.8e-06 25.5 0.0 2.1e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 LisH PARM PF17061.5 KFP01980.1 - 0.56 10.3 21.6 0.9 9.6 21.6 1.3 1 0 0 1 1 1 0 PARM Macoilin PF09726.9 KFP01980.1 - 2.1 6.8 9.8 2.7 6.5 9.8 1.1 1 0 0 1 1 1 0 Macoilin family Peptidase_S64 PF08192.11 KFP01980.1 - 3.2 6.1 12.5 4.5 5.6 12.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 Presenilin PF01080.17 KFP01980.1 - 3.9 6.1 5.2 5.2 5.7 5.2 1.2 1 0 0 1 1 1 0 Presenilin CENP-T_C PF15511.6 KFP01981.1 - 4.3e-29 100.8 0.1 4.8e-29 100.6 0.1 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KFP01981.1 - 4.5e-08 33.4 0.0 5.6e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KFP01981.1 - 7.4e-05 23.0 0.0 9.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFP01981.1 - 0.0016 18.8 0.1 0.0019 18.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KFP01981.1 - 0.095 12.7 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated NTF2 PF02136.20 KFP01982.1 - 5.4e-33 114.1 0.0 6.1e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 KFP01982.1 - 0.073 13.5 0.0 0.088 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Pkinase PF00069.25 KFP01983.1 - 1.4e-69 234.4 0.0 1.6e-69 234.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP01983.1 - 1.3e-31 109.8 0.0 1.7e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP01983.1 - 8.7e-06 25.2 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFP01983.1 - 0.00043 19.7 0.0 0.00067 19.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP01983.1 - 0.0024 17.9 0.2 0.34 10.8 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Trypsin PF00089.26 KFP01984.1 - 1.1e-39 136.6 0.3 1.7e-39 135.9 0.3 1.3 1 1 0 1 1 1 1 Trypsin DUF316 PF03761.15 KFP01984.1 - 0.018 14.6 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 Peptidase_C37 PF05416.12 KFP01984.1 - 0.16 10.5 0.1 0.19 10.2 0.1 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Trypsin PF00089.26 KFP01985.1 - 0.029 14.2 0.1 0.033 14.0 0.1 1.1 1 0 0 1 1 1 0 Trypsin Sec6 PF06046.13 KFP01986.1 - 2.9e-119 399.1 2.4 2.9e-119 399.1 2.4 1.4 2 0 0 2 2 2 1 Exocyst complex component Sec6 Sec8_exocyst PF04048.14 KFP01986.1 - 0.014 15.3 2.1 0.049 13.5 0.8 2.5 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF720 PF05302.11 KFP01986.1 - 0.03 14.2 3.5 0.086 12.7 3.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF720) SOAR PF16533.5 KFP01986.1 - 1.4 8.9 5.6 2.4 8.2 0.5 3.3 3 0 0 3 3 3 0 STIM1 Orai1-activating region E2F_CC-MB PF16421.5 KFP01987.1 - 2.7e-30 104.6 0.2 4.1e-30 104.0 0.2 1.3 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 KFP01987.1 - 2.1e-14 53.3 0.2 4.6e-14 52.2 0.2 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Rx_N PF18052.1 KFP01987.1 - 0.068 13.4 0.2 0.12 12.6 0.2 1.5 1 0 0 1 1 1 0 Rx N-terminal domain XhlA PF10779.9 KFP01987.1 - 1.4 9.2 4.6 2.7 8.3 4.6 1.4 1 0 0 1 1 1 0 Haemolysin XhlA DUF3361 PF11841.8 KFP01988.1 - 2.4e-55 186.7 1.8 6e-55 185.4 1.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.13 KFP01988.1 - 7.7e-43 146.7 0.3 1.2e-42 146.0 0.3 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 KFP01988.1 - 1.1e-35 123.1 0.0 1.9e-35 122.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DUF1704 PF08014.11 KFP01989.1 - 1.4e-12 47.4 0.0 2.8e-12 46.4 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1704) LCAT PF02450.15 KFP01990.1 - 5.8e-119 397.8 2.1 3.1e-118 395.4 2.1 1.8 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 KFP01990.1 - 2.4e-05 25.1 0.0 3.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFP01990.1 - 0.00023 20.5 0.0 0.00049 19.5 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF915 PF06028.11 KFP01990.1 - 0.026 13.8 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF900 PF05990.12 KFP01990.1 - 0.036 13.6 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.13 KFP01990.1 - 0.05 13.5 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase DUF1749 PF08538.10 KFP01990.1 - 0.1 11.7 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) UBA_3 PF09288.10 KFP01990.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Adaptin_N PF01602.20 KFP01991.1 - 2.6e-32 112.1 0.1 5.6e-26 91.2 0.0 2.0 2 0 0 2 2 2 2 Adaptin N terminal region PuR_N PF09182.10 KFP01991.1 - 0.056 13.4 0.0 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal Ank_4 PF13637.6 KFP01992.1 - 5.1e-55 183.2 17.6 5.5e-12 46.0 0.1 6.0 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP01992.1 - 1.2e-53 179.6 10.7 2.5e-15 56.8 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP01992.1 - 8e-44 142.6 6.5 7.1e-05 22.9 0.0 9.2 9 0 0 9 9 9 8 Ankyrin repeat Ank PF00023.30 KFP01992.1 - 1.2e-41 139.3 11.7 1.3e-06 28.6 0.0 9.1 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 KFP01992.1 - 4.5e-38 128.8 12.5 4.5e-09 36.4 0.1 8.5 1 1 8 9 9 9 9 Ankyrin repeats (many copies) INTS5_C PF14838.6 KFP01992.1 - 0.0092 14.7 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 Integrator complex subunit 5 C-terminus Arm PF00514.23 KFP01993.1 - 3.9e-32 109.3 1.0 4.7e-08 32.8 0.0 7.2 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 KFP01993.1 - 4.6e-06 26.3 1.3 0.003 17.1 0.0 2.7 2 1 0 2 2 2 2 Armadillo-like Atx10homo_assoc PF09759.9 KFP01993.1 - 0.00021 21.2 0.3 0.018 15.1 0.1 3.1 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 KFP01993.1 - 0.0035 17.5 0.2 4.3 7.9 0.0 3.8 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 KFP01993.1 - 0.065 13.6 0.8 0.53 10.7 0.2 2.4 2 0 0 2 2 2 0 HEAT repeats HEAT_EZ PF13513.6 KFP01993.1 - 0.072 13.6 0.3 3.7 8.2 0.1 3.6 3 1 1 4 4 4 0 HEAT-like repeat zf-C3HC PF07967.13 KFP01994.1 - 1.9e-34 118.5 10.9 2.1e-34 118.4 2.8 3.1 3 0 0 3 3 3 1 C3HC zinc finger-like Rsm1 PF08600.10 KFP01994.1 - 1.6e-13 50.6 12.8 1.8e-09 37.6 1.7 3.3 3 0 0 3 3 3 2 Rsm1-like UQ_con PF00179.26 KFP01995.1 - 1.5e-37 128.3 0.0 1.9e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Uteroglobin PF01099.17 KFP01995.1 - 0.14 12.5 1.2 0.27 11.6 0.9 1.6 1 1 0 2 2 2 0 Uteroglobin family Nrf1_DNA-bind PF10491.9 KFP01996.1 - 1.4e-116 387.6 0.1 2.1e-116 387.0 0.1 1.3 1 0 0 1 1 1 1 NLS-binding and DNA-binding and dimerisation domains of Nrf1 Nrf1_activ_bdg PF10492.9 KFP01996.1 - 0.00088 19.9 6.7 0.00088 19.9 6.7 5.7 3 2 0 3 3 3 1 Nrf1 activator activation site binding domain DUF5008 PF16400.5 KFP01996.1 - 0.054 13.6 0.0 0.21 11.7 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5008) DUF3459 PF11941.8 KFP01996.1 - 0.092 13.1 0.6 0.37 11.2 0.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Peptidase_M23 PF01551.22 KFP01996.1 - 0.28 11.4 3.8 0.39 10.9 1.0 2.5 1 1 2 3 3 3 0 Peptidase family M23 AdoHcyase PF05221.17 KFP01998.1 - 3.6e-33 115.0 0.1 1.1e-32 113.4 0.1 1.6 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase PT PF04886.12 KFP01999.1 - 6.7e-22 76.7 198.6 1.8e+04 -159.2 198.6 9.5 1 1 0 1 1 1 0 PT repeat Ank_2 PF12796.7 KFP02001.1 - 3.2e-17 62.9 0.1 1e-16 61.3 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP02001.1 - 7.6e-17 61.5 0.0 2.1e-11 44.1 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFP02001.1 - 4.9e-14 52.0 0.0 5.1e-06 26.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFP02001.1 - 9.4e-14 50.2 0.0 4e-05 23.7 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat SH3_1 PF00018.28 KFP02001.1 - 1.3e-11 44.0 1.2 2.6e-11 43.0 1.2 1.5 1 0 0 1 1 1 1 SH3 domain Ank_5 PF13857.6 KFP02001.1 - 7.7e-10 38.8 0.6 4.8e-08 33.1 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SH3_9 PF14604.6 KFP02001.1 - 1.3e-09 37.8 0.2 2.9e-09 36.6 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP02001.1 - 3.3e-07 29.9 0.0 6.5e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain RA PF00788.23 KFP02001.1 - 0.0011 19.6 0.4 0.036 14.7 0.4 2.7 1 1 0 1 1 1 1 Ras association (RalGDS/AF-6) domain cwf21 PF08312.12 KFP02001.1 - 2.2 8.5 6.2 1.9 8.7 3.5 2.4 2 0 0 2 2 2 0 cwf21 domain ATG16 PF08614.11 KFP02002.1 - 2.7e-05 24.5 3.1 2.7e-05 24.5 3.1 1.8 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) FAM76 PF16046.5 KFP02002.1 - 8.6e-05 22.0 1.2 0.00016 21.2 1.2 1.6 1 0 0 1 1 1 1 FAM76 protein DUF3287 PF11690.8 KFP02002.1 - 0.0029 17.3 1.4 0.011 15.5 0.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3287) SlyX PF04102.12 KFP02002.1 - 0.0038 17.8 8.5 0.0038 17.8 8.5 2.7 2 1 1 3 3 3 1 SlyX Spc7 PF08317.11 KFP02002.1 - 0.0063 15.4 8.2 0.012 14.6 8.2 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Filament PF00038.21 KFP02002.1 - 0.0073 15.9 8.2 0.015 14.9 8.2 1.4 1 0 0 1 1 1 1 Intermediate filament protein TMF_DNA_bd PF12329.8 KFP02002.1 - 0.07 13.1 11.4 0.61 10.1 7.1 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.8 KFP02002.1 - 0.13 11.6 9.1 0.3 10.4 9.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF16 PF01519.16 KFP02002.1 - 0.15 12.5 8.0 0.047 14.2 4.5 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF2730 PF10805.8 KFP02002.1 - 0.2 11.7 3.3 1.6 8.9 3.3 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) SKA1 PF07160.12 KFP02002.1 - 0.23 11.3 8.9 0.48 10.2 8.9 1.6 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 HemX PF04375.14 KFP02002.1 - 0.36 10.1 9.9 0.75 9.0 9.9 1.5 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase YabA PF06156.13 KFP02002.1 - 0.66 10.6 7.2 3.2 8.4 5.0 2.5 1 1 1 2 2 2 0 Initiation control protein YabA DUF4407 PF14362.6 KFP02002.1 - 0.69 9.2 5.2 1.2 8.4 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) COG2 PF06148.11 KFP02002.1 - 1.4 9.0 6.7 3.9 7.6 3.8 2.7 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ABC_tran_CTD PF16326.5 KFP02002.1 - 1.6 9.1 11.0 6.4 7.1 10.9 2.1 1 1 0 1 1 1 0 ABC transporter C-terminal domain FlaC_arch PF05377.11 KFP02002.1 - 2 8.8 4.8 1.5 9.3 1.9 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) OmpH PF03938.14 KFP02002.1 - 2.4 8.5 15.2 2.1 8.7 13.4 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) NPV_P10 PF05531.12 KFP02002.1 - 3.6 8.1 10.2 12 6.4 8.3 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein KASH_CCD PF14662.6 KFP02002.1 - 3.9 7.3 17.1 1.2 8.9 3.4 2.6 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH TMF_TATA_bd PF12325.8 KFP02002.1 - 4.7 7.5 14.5 3.8 7.8 11.3 2.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FA_desaturase PF00487.24 KFP02003.1 - 5.6e-25 88.6 15.3 5.6e-25 88.6 15.3 1.6 2 0 0 2 2 2 1 Fatty acid desaturase Lipid_DES PF08557.10 KFP02003.1 - 0.0021 17.5 0.2 0.0043 16.5 0.2 1.6 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) AAA PF00004.29 KFP02004.1 - 1e-94 313.9 0.0 1.5e-48 164.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Nucleolin_bd PF16725.5 KFP02004.1 - 2.3e-28 97.6 0.2 6.3e-28 96.2 0.2 1.7 1 0 0 1 1 1 1 Nucleolin binding domain AAA_lid_3 PF17862.1 KFP02004.1 - 3.1e-24 84.5 0.1 2.2e-11 43.3 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 KFP02004.1 - 8.8e-14 51.5 0.0 1.2e-05 25.2 0.0 3.1 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KFP02004.1 - 1.3e-12 48.2 0.0 6.2e-05 23.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KFP02004.1 - 1.5e-11 45.0 7.8 0.0078 16.6 0.0 5.6 4 2 1 6 6 5 2 AAA ATPase domain AAA_22 PF13401.6 KFP02004.1 - 2.9e-11 43.8 5.1 0.00039 20.7 0.2 5.0 4 2 1 5 5 3 2 AAA domain AAA_5 PF07728.14 KFP02004.1 - 3.9e-10 39.9 1.5 0.00015 21.8 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KFP02004.1 - 7.6e-09 35.2 0.0 0.0042 16.3 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 KFP02004.1 - 1.8e-08 34.5 0.0 0.0076 16.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KFP02004.1 - 5.5e-08 33.1 0.0 0.0049 17.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KFP02004.1 - 9e-08 31.7 0.3 0.0051 16.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KFP02004.1 - 7.2e-07 29.6 0.0 0.055 13.9 0.0 2.9 2 1 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 KFP02004.1 - 9.2e-07 29.2 0.0 0.045 14.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KFP02004.1 - 1.8e-06 27.4 0.2 0.0032 16.8 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin Viral_helicase1 PF01443.18 KFP02004.1 - 1.9e-06 27.8 0.0 0.038 13.7 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 KFP02004.1 - 2.1e-06 27.6 0.0 0.075 12.8 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 KFP02004.1 - 2.5e-06 28.0 0.0 0.028 15.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KFP02004.1 - 6.7e-06 26.1 0.6 0.046 13.6 0.0 3.0 2 1 0 2 2 2 2 NACHT domain TsaE PF02367.17 KFP02004.1 - 7.9e-06 25.9 0.0 0.075 13.0 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 KFP02004.1 - 9.1e-06 25.6 0.0 0.058 13.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KFP02004.1 - 1.7e-05 24.3 2.6 0.66 9.3 0.0 4.3 3 1 1 4 4 4 2 KaiC ABC_tran PF00005.27 KFP02004.1 - 3.1e-05 24.5 0.0 0.41 11.2 0.0 2.9 2 1 0 2 2 2 2 ABC transporter Rad17 PF03215.15 KFP02004.1 - 3.4e-05 23.8 0.1 0.11 12.4 0.0 2.8 2 1 1 3 3 2 2 Rad17 P-loop domain AAA_17 PF13207.6 KFP02004.1 - 4.4e-05 23.9 0.6 0.61 10.5 0.0 3.2 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.26 KFP02004.1 - 7.9e-05 22.4 0.0 0.5 10.1 0.0 3.4 2 1 0 2 2 2 1 Sigma-54 interaction domain Cytidylate_kin2 PF13189.6 KFP02004.1 - 0.00016 21.9 0.0 0.13 12.3 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase-like family Vps4_C PF09336.10 KFP02004.1 - 0.00029 20.8 0.2 0.38 10.8 0.0 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Sigma54_activ_2 PF14532.6 KFP02004.1 - 0.00031 20.9 0.8 0.6 10.2 0.0 2.7 3 0 0 3 3 2 2 Sigma-54 interaction domain NB-ARC PF00931.22 KFP02004.1 - 0.00031 20.0 0.0 1.1 8.4 0.0 2.8 3 0 0 3 3 3 2 NB-ARC domain AAA_11 PF13086.6 KFP02004.1 - 0.00037 20.4 0.2 1.2 8.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 KFP02004.1 - 0.00075 19.1 4.6 1.7 8.2 0.2 3.8 2 2 1 4 4 4 2 AAA domain AAA_7 PF12775.7 KFP02004.1 - 0.00096 18.7 0.0 2 7.9 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region DUF2075 PF09848.9 KFP02004.1 - 0.0022 17.3 0.0 1.2 8.3 0.0 3.2 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KFP02004.1 - 0.0034 16.9 0.1 1.6 8.1 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein PduV-EutP PF10662.9 KFP02004.1 - 0.0057 16.4 0.0 3 7.6 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 KFP02004.1 - 0.0066 15.6 0.0 0.35 10.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 KFP02004.1 - 0.0066 15.6 0.0 2.7 7.0 0.0 2.6 2 1 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 KFP02004.1 - 0.0099 15.6 0.0 4.9 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KFP02004.1 - 0.01 15.7 0.0 6.4 6.7 0.0 3.2 2 1 1 3 3 3 0 NTPase SKI PF01202.22 KFP02004.1 - 0.011 15.9 1.0 2.6 8.2 0.0 3.6 4 0 0 4 4 4 0 Shikimate kinase ATPase_2 PF01637.18 KFP02004.1 - 0.012 15.5 0.1 16 5.3 0.0 3.6 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KFP02004.1 - 0.022 15.1 0.5 9.9 6.5 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFP02004.1 - 0.054 13.2 0.0 8.1 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF4559 PF15112.6 KFP02004.1 - 0.068 12.8 1.0 0.13 12.0 0.4 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4559) DAP3 PF10236.9 KFP02004.1 - 0.16 11.2 0.1 6.1 5.9 0.0 2.8 2 1 1 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Zot PF05707.12 KFP02004.1 - 0.16 11.6 0.1 5.8 6.5 0.0 3.0 2 2 1 3 3 2 0 Zonular occludens toxin (Zot) Phage_Gp17 PF17549.2 KFP02004.1 - 0.69 9.9 2.5 0.45 10.5 0.1 1.8 2 0 0 2 2 1 0 Gene Product 17 AAA_23 PF13476.6 KFP02004.1 - 2 8.9 7.1 15 6.1 0.0 3.9 4 0 0 4 4 4 0 AAA domain Cornichon PF03311.14 KFP02005.1 - 1e-48 164.6 9.7 1.2e-48 164.4 9.7 1.0 1 0 0 1 1 1 1 Cornichon protein DUF2650 PF10853.8 KFP02005.1 - 2.2 8.0 7.5 0.36 10.6 1.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2650) WD40 PF00400.32 KFP02006.1 - 8e-28 96.1 11.4 6.4e-06 26.8 0.0 6.3 5 1 1 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP02006.1 - 4.6e-08 33.2 0.2 0.12 12.7 0.0 5.1 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP02006.1 - 1.8e-05 24.7 0.0 0.00029 20.8 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFP02006.1 - 0.003 16.6 0.1 0.032 13.2 0.0 2.5 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KFP02006.1 - 0.056 13.4 0.1 72 3.5 0.1 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat RVT_1 PF00078.27 KFP02007.1 - 0.0049 16.4 0.0 0.0078 15.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) REC114-like PF15165.6 KFP02008.1 - 1.8e-87 293.0 3.0 5.9e-85 284.8 3.0 2.0 1 1 0 1 1 1 1 Meiotic recombination protein REC114-like Tryp_alpha_amyl PF00234.22 KFP02008.1 - 0.03 14.7 6.5 0.045 14.2 6.5 1.3 1 0 0 1 1 1 0 Protease inhibitor/seed storage/LTP family Ig_3 PF13927.6 KFP02009.1 - 3.2e-21 75.7 4.5 1e-11 45.3 0.2 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP02009.1 - 4.7e-16 58.6 0.2 6e-12 45.5 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP02009.1 - 9.7e-12 45.1 1.8 1.2e-05 25.5 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP02009.1 - 2.1e-10 40.6 1.5 7.8e-06 26.0 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_4 PF16680.5 KFP02009.1 - 0.001 19.3 0.0 0.19 12.0 0.0 2.5 2 0 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFP02009.1 - 0.0038 17.6 0.0 1.5 9.3 0.0 2.6 2 0 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFP02009.1 - 0.0078 15.8 0.0 4 7.1 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP02010.1 - 1.3e-13 50.9 0.4 2.8e-06 27.4 0.1 2.6 2 1 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 KFP02010.1 - 6.5e-13 49.1 0.0 5.7e-06 26.8 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP02010.1 - 2.5e-09 37.1 0.2 0.00058 19.9 0.1 2.9 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP02010.1 - 7.5e-09 35.8 0.5 6.6e-05 23.2 0.2 3.0 2 1 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.15 KFP02010.1 - 2.1e-07 31.2 0.2 1.1e-06 29.0 0.1 2.2 3 0 0 3 3 3 1 Immunoglobulin C1-set domain V-set PF07686.17 KFP02010.1 - 3.1e-07 30.5 0.1 3.1e-06 27.3 0.0 2.4 2 1 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP02010.1 - 5.9e-07 29.5 0.8 1.4e-05 25.0 0.1 2.9 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain FAM163 PF15069.6 KFP02010.1 - 0.029 14.8 0.1 0.06 13.8 0.1 1.5 1 0 0 1 1 1 0 FAM163 family FAM176 PF14851.6 KFP02010.1 - 0.049 13.3 0.2 0.084 12.5 0.2 1.3 1 0 0 1 1 1 0 FAM176 family Ig_6 PF18452.1 KFP02010.1 - 0.086 12.4 0.5 0.21 11.2 0.0 1.9 3 0 0 3 3 3 0 Immunoglobulin domain Zona_pellucida PF00100.23 KFP02011.1 - 1e-46 159.9 0.0 1.2e-46 159.7 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Lysyl_oxidase PF01186.17 KFP02012.1 - 1e-95 319.2 3.7 1.2e-95 319.1 3.7 1.0 1 0 0 1 1 1 1 Lysyl oxidase CARDB PF07705.11 KFP02012.1 - 0.00044 20.5 0.0 0.0062 16.8 0.0 2.3 2 0 0 2 2 2 1 CARDB Integrin_alpha2 PF08441.12 KFP02013.1 - 1.6e-34 119.6 0.0 1.8e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Integrin alpha Alpha_adaptinC2 PF02883.20 KFP02013.1 - 0.11 12.8 0.0 9.4 6.6 0.1 2.6 2 1 1 3 3 3 0 Adaptin C-terminal domain G-patch PF01585.23 KFP02014.1 - 1.4e-13 50.5 1.0 3.7e-13 49.1 1.0 1.7 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 KFP02014.1 - 6.1e-07 29.6 8.9 6.1e-07 29.6 8.9 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP02014.1 - 0.0018 18.6 2.0 0.0047 17.3 2.0 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type G-patch_2 PF12656.7 KFP02014.1 - 0.0038 17.3 0.3 0.02 15.0 0.3 2.4 1 0 0 1 1 1 1 G-patch domain zf-C2H2_2 PF12756.7 KFP02014.1 - 0.019 15.3 2.1 0.043 14.1 2.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.12 KFP02014.1 - 0.054 13.6 5.3 0.13 12.4 5.3 1.7 1 0 0 1 1 1 0 DBF zinc finger Frizzled PF01534.17 KFP02015.1 - 9.5e-140 465.2 20.0 1.2e-139 464.8 20.0 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 KFP02015.1 - 1.1e-51 174.1 10.6 8.5e-34 116.5 4.5 2.5 3 0 0 3 3 3 2 Fz domain RPN6_N PF18055.1 KFP02016.1 - 5.3e-19 68.7 0.1 5.5e-19 68.6 0.1 1.0 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN6 N-terminal domain SEN1_N PF12726.7 KFP02016.1 - 0.032 12.4 0.0 0.032 12.4 0.0 1.0 1 0 0 1 1 1 0 SEN1 N terminal Myosin_head PF00063.21 KFP02017.1 - 2.2e-206 687.2 6.7 8.1e-181 602.7 6.0 2.0 2 0 0 2 2 2 2 Myosin head (motor domain) Zeta_toxin PF06414.12 KFP02017.1 - 0.024 13.9 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 KFP02017.1 - 0.025 14.8 0.0 0.069 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KFP02017.1 - 0.028 14.1 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 KFP02017.1 - 0.047 14.1 0.0 0.15 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Hpr_kinase_C PF07475.12 KFP02017.1 - 0.16 11.4 1.4 9.8 5.7 0.3 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain WIYLD PF10440.9 KFP02017.1 - 0.19 11.6 0.9 5.7 6.8 0.1 3.3 2 1 1 3 3 3 0 Ubiquitin-binding WIYLD domain Pkinase PF00069.25 KFP02018.1 - 1.2e-46 159.3 0.0 1.9e-46 158.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP02018.1 - 7.7e-29 100.8 0.0 1.2e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP02018.1 - 1.1e-05 24.4 0.0 2.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KFP02019.1 - 6.8e-21 74.8 0.0 8e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP02019.1 - 2.2e-06 27.2 0.0 2.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase HEXIM PF15313.6 KFP02020.1 - 7.4e-62 207.7 4.3 1.3e-61 207.0 4.3 1.4 1 0 0 1 1 1 1 Hexamethylene bis-acetamide-inducible protein HIP1_clath_bdg PF16515.5 KFP02020.1 - 0.6 10.7 9.9 3.7 8.2 6.4 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Shugoshin_N PF07558.11 KFP02020.1 - 5.7 6.9 11.1 0.17 11.8 1.0 2.4 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region NMT_C PF02799.15 KFP02021.1 - 2.1e-83 279.0 0.0 3.1e-83 278.4 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KFP02021.1 - 5.6e-75 250.6 0.0 8.9e-75 249.9 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 KFP02021.1 - 0.00016 21.9 0.0 0.00038 20.7 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KFP02021.1 - 0.056 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CoaE PF01121.20 KFP02022.1 - 2.4e-60 203.3 0.0 2.8e-60 203.0 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KFP02022.1 - 0.00028 21.4 0.0 0.0013 19.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFP02022.1 - 0.00063 19.9 0.0 0.0018 18.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KFP02022.1 - 0.011 16.2 0.0 0.054 13.9 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_31 PF13614.6 KFP02022.1 - 0.14 12.1 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sec10 PF07393.11 KFP02022.1 - 0.15 10.5 0.1 0.23 9.9 0.1 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec10 AAA_28 PF13521.6 KFP02022.1 - 0.16 12.2 0.0 0.46 10.7 0.0 1.8 2 1 1 3 3 3 0 AAA domain C1q PF00386.21 KFP02023.1 - 1.9e-17 63.6 0.0 2.1e-17 63.5 0.0 1.0 1 0 0 1 1 1 1 C1q domain Kinesin PF00225.23 KFP02024.1 - 5.4e-110 367.4 0.0 7.1e-110 367.0 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFP02024.1 - 5.8e-26 91.2 0.0 4e-24 85.2 0.0 2.3 2 0 0 2 2 2 2 Microtubule binding V-set PF07686.17 KFP02025.1 - 4.3e-12 46.2 0.0 1.4e-07 31.6 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP02025.1 - 5.8e-09 36.4 0.0 0.0063 17.1 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP02025.1 - 6.6e-08 32.6 0.0 0.0082 16.3 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP02025.1 - 1.7e-05 24.8 0.0 0.13 12.3 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP02025.1 - 0.00041 20.6 0.0 0.1 12.9 0.0 2.8 2 1 0 2 2 2 1 Immunoglobulin domain Ig_6 PF18452.1 KFP02025.1 - 0.012 15.1 0.0 5.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain Receptor_2B4 PF11465.8 KFP02025.1 - 0.097 12.9 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 RPAP3_C PF13877.6 KFP02026.1 - 4.6e-19 68.7 0.0 9.6e-19 67.7 0.0 1.5 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 Dynein_attach_N PF15867.5 KFP02026.1 - 3.6e-06 26.8 0.1 7.3e-06 25.8 0.1 1.6 1 0 0 1 1 1 1 Dynein attachment factor N-terminus GTP_EFTU PF00009.27 KFP02027.1 - 6.1e-46 156.4 0.0 9.3e-46 155.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KFP02027.1 - 7.9e-39 133.0 9.5 1.3e-38 132.3 9.5 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KFP02027.1 - 1.1e-23 83.2 0.0 2.4e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KFP02027.1 - 9.8e-23 80.0 0.0 2.2e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFP02027.1 - 9.8e-13 48.3 0.0 2.7e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KFP02027.1 - 3e-08 33.6 0.0 8.3e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Septin PF00735.18 KFP02027.1 - 0.06 12.6 0.0 0.099 11.9 0.0 1.2 1 0 0 1 1 1 0 Septin Connexin PF00029.19 KFP02028.1 - 2.3e-97 325.4 0.1 2.6e-97 325.2 0.1 1.0 1 0 0 1 1 1 1 Connexin Reprolysin PF01421.19 KFP02029.1 - 5.1e-66 222.4 0.0 1e-65 221.4 0.0 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Disintegrin PF00200.23 KFP02029.1 - 1.5e-15 57.7 29.5 1.5e-15 57.7 29.5 3.0 2 0 0 2 2 2 1 Disintegrin Reprolysin_3 PF13582.6 KFP02029.1 - 6.4e-10 39.6 0.1 1.2e-09 38.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFP02029.1 - 4.6e-09 36.7 0.4 1e-08 35.6 0.4 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 EGF_2 PF07974.13 KFP02029.1 - 0.0004 20.7 10.7 0.0004 20.7 10.7 5.8 6 1 0 6 6 6 2 EGF-like domain Reprolysin_2 PF13574.6 KFP02029.1 - 0.00075 19.5 0.1 0.002 18.0 0.1 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_Tenascin PF18720.1 KFP02029.1 - 0.0012 18.9 3.4 0.0012 18.9 3.4 4.1 4 0 0 4 4 4 1 Tenascin EGF domain Reprolysin_4 PF13583.6 KFP02029.1 - 0.0042 16.7 0.2 0.0092 15.6 0.2 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DicB PF05358.11 KFP02030.1 - 0.31 11.2 2.1 1.1 9.5 0.1 2.6 3 0 0 3 3 3 0 DicB protein MEIOC PF15189.6 KFP02031.1 - 2.3e-83 277.8 2.4 2.7e-83 277.6 2.4 1.0 1 0 0 1 1 1 1 Meiosis-specific coiled-coil domain-containing protein MEIOC CAMSAP_CC1 PF17095.5 KFP02031.1 - 0.0045 16.8 1.3 0.014 15.2 0.1 2.1 2 0 0 2 2 2 1 Spectrin-binding region of Ca2+-Calmodulin NTPase_1 PF03266.15 KFP02031.1 - 0.0069 16.3 0.0 0.0096 15.8 0.0 1.2 1 0 0 1 1 1 1 NTPase DUF1517 PF07466.11 KFP02031.1 - 0.13 12.4 1.1 0.14 12.2 0.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) AAA PF00004.29 KFP02032.1 - 1.1e-57 194.1 0.0 1.7e-41 141.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.18 KFP02032.1 - 1.1e-12 47.9 0.0 3.1e-11 43.3 0.0 2.7 3 0 0 3 3 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_lid_3 PF17862.1 KFP02032.1 - 2.8e-10 39.8 0.3 6e-10 38.8 0.3 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KFP02032.1 - 1.3e-09 38.5 0.2 0.014 15.7 0.0 4.3 2 2 2 4 4 4 2 AAA domain CDC48_2 PF02933.17 KFP02032.1 - 7.6e-09 35.2 0.8 8.7e-08 31.8 0.0 2.7 3 0 0 3 3 2 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.6 KFP02032.1 - 2.7e-08 34.4 0.0 0.0034 17.8 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 KFP02032.1 - 4.4e-08 33.0 0.0 0.01 15.6 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KFP02032.1 - 5.7e-08 33.1 0.1 0.013 15.9 0.0 3.3 4 0 0 4 4 2 2 RNA helicase AAA_2 PF07724.14 KFP02032.1 - 5.9e-08 33.0 0.0 7.6e-06 26.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KFP02032.1 - 6.6e-07 29.4 0.0 0.025 14.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KFP02032.1 - 7.9e-07 29.1 0.0 0.001 19.0 0.1 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KFP02032.1 - 2.1e-06 28.3 0.0 0.017 15.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 KFP02032.1 - 2.6e-06 26.9 0.0 0.046 12.9 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 KFP02032.1 - 2.7e-06 27.6 0.0 0.092 12.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KFP02032.1 - 1.1e-05 24.9 0.1 0.0043 16.5 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 KFP02032.1 - 1.7e-05 24.9 0.1 0.29 11.0 0.0 4.0 2 2 2 4 4 4 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KFP02032.1 - 3.1e-05 23.8 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 KFP02032.1 - 3.9e-05 23.6 0.0 0.058 13.4 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KFP02032.1 - 9.7e-05 22.3 0.0 0.73 9.7 0.0 3.6 3 1 0 3 3 3 2 NACHT domain AAA_17 PF13207.6 KFP02032.1 - 0.00049 20.5 0.0 1.5 9.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 KFP02032.1 - 0.0011 18.4 0.1 0.02 14.3 0.0 2.8 2 1 1 3 3 3 1 KaiC AAA_3 PF07726.11 KFP02032.1 - 0.0026 17.6 0.0 0.38 10.6 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KFP02032.1 - 0.0026 18.0 0.0 0.29 11.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KFP02032.1 - 0.003 16.9 0.0 1.3 8.2 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin ABC_tran PF00005.27 KFP02032.1 - 0.0034 17.9 0.0 0.017 15.7 0.0 2.2 2 0 0 2 2 1 1 ABC transporter Sigma54_activat PF00158.26 KFP02032.1 - 0.004 16.9 0.0 1.6 8.4 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 KFP02032.1 - 0.0049 16.4 0.0 0.099 12.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region KTI12 PF08433.10 KFP02032.1 - 0.0052 16.3 0.7 3.9 6.8 0.0 3.4 4 0 0 4 4 4 1 Chromatin associated protein KTI12 IstB_IS21 PF01695.17 KFP02032.1 - 0.0084 15.9 0.0 0.29 10.9 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein NB-ARC PF00931.22 KFP02032.1 - 0.0091 15.2 0.0 1 8.5 0.1 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.6 KFP02032.1 - 0.0093 15.6 0.2 2 7.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 KFP02032.1 - 0.015 15.1 0.0 1.6 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KFP02032.1 - 0.015 15.2 0.1 0.2 11.5 0.0 2.7 3 1 0 3 3 3 0 Rad17 P-loop domain Parvo_NS1 PF01057.17 KFP02032.1 - 0.016 14.3 0.0 2.2 7.3 0.0 2.6 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 KFP02032.1 - 0.052 13.9 0.2 4.1 7.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 KFP02032.1 - 0.068 13.1 0.0 16 5.3 0.0 3.1 2 1 0 2 2 2 0 NTPase CPT PF07931.12 KFP02032.1 - 0.087 12.7 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein wnt PF00110.19 KFP02033.1 - 9.8e-125 416.2 15.7 1.1e-124 416.1 15.7 1.0 1 0 0 1 1 1 1 wnt family V-SNARE_C PF12352.8 KFP02034.1 - 3.1e-18 65.8 1.4 3.1e-18 65.8 1.4 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KFP02034.1 - 4.5e-06 26.5 0.8 6.9e-06 25.9 0.1 1.7 2 0 0 2 2 2 1 Sec20 V-SNARE PF05008.15 KFP02034.1 - 0.00053 20.3 1.6 0.0013 19.1 1.6 1.6 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus EF-G-binding_N PF07299.11 KFP02034.1 - 0.008 16.7 1.9 0.014 15.9 0.6 2.1 2 0 0 2 2 2 1 Elongation factor G-binding protein, N-terminal EzrA PF06160.12 KFP02034.1 - 0.014 13.6 5.5 0.018 13.3 5.5 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA HSCB_C PF07743.13 KFP02034.1 - 0.051 14.1 1.0 0.45 11.0 0.4 2.5 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain DUF2344 PF10105.9 KFP02034.1 - 0.063 13.1 0.2 0.085 12.7 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Ran-binding PF05508.11 KFP02034.1 - 0.07 12.1 1.9 0.1 11.6 1.9 1.1 1 0 0 1 1 1 0 RanGTP-binding protein GIT_CC PF16559.5 KFP02034.1 - 0.08 12.8 2.0 1.7 8.6 0.0 2.7 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cytokin_check_N PF10407.9 KFP02034.1 - 0.085 12.8 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus DUF1690 PF07956.11 KFP02034.1 - 0.18 12.3 5.9 0.38 11.2 5.9 1.6 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) FlxA PF14282.6 KFP02034.1 - 0.28 11.2 4.5 1.2 9.2 0.3 2.3 1 1 1 2 2 2 0 FlxA-like protein zf-U11-48K PF05253.12 KFP02035.1 - 5.7e-18 64.4 14.3 4.6e-09 36.0 6.8 2.4 2 0 0 2 2 2 2 U11-48K-like CHHC zinc finger zf-TRAF_2 PF15965.5 KFP02035.1 - 0.024 15.1 1.9 0.04 14.4 1.9 1.4 1 0 0 1 1 1 0 TRAF-like zinc-finger Peptidase_C48 PF02902.19 KFP02036.1 - 8.1e-34 117.4 1.7 8.7e-20 71.5 0.3 2.6 2 1 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain Myosin_head PF00063.21 KFP02037.1 - 2.1e-237 789.7 0.8 2.1e-237 789.7 0.8 1.8 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin-VI_CBD PF16521.5 KFP02037.1 - 1.5e-45 153.1 1.1 3.1e-44 148.9 0.0 3.2 4 0 0 4 4 4 1 Myosin VI cargo binding domain Myosin_N PF02736.19 KFP02037.1 - 0.00022 21.0 0.0 0.00042 20.1 0.0 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain IQ PF00612.27 KFP02037.1 - 0.0018 17.9 1.5 0.0048 16.6 1.5 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif AAA_16 PF13191.6 KFP02037.1 - 0.51 10.7 0.0 0.51 10.7 0.0 3.0 3 1 0 3 3 3 0 AAA ATPase domain SEA PF01390.20 KFP02038.1 - 1.1e-31 109.1 2.3 9.1e-16 57.9 0.3 2.4 2 0 0 2 2 2 2 SEA domain DUF4214 PF13946.6 KFP02038.1 - 0.02 14.9 0.0 0.061 13.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4214) EGF PF00008.27 KFP02038.1 - 0.046 14.0 9.8 0.95 9.8 2.1 2.4 2 0 0 2 2 2 0 EGF-like domain Plasmod_Pvs28 PF06247.11 KFP02038.1 - 0.065 13.5 2.6 0.15 12.4 2.6 1.6 1 0 0 1 1 1 0 Pvs28 EGF domain cEGF PF12662.7 KFP02038.1 - 0.21 11.5 2.0 0.64 10.0 2.0 1.8 1 0 0 1 1 1 0 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 KFP02038.1 - 0.51 10.4 4.3 1.2 9.2 4.3 1.7 1 0 0 1 1 1 0 MSP1 EGF domain 1 EGF_3 PF12947.7 KFP02038.1 - 4.1 7.7 8.3 0.22 11.8 1.8 2.0 2 0 0 2 2 2 0 EGF domain Yae1_N PF09811.9 KFP02039.1 - 4.5e-08 32.7 27.9 75 3.1 27.9 3.2 1 1 0 1 1 1 1 Essential protein Yae1, N terminal 7tm_1 PF00001.21 KFP02040.1 - 1.9e-82 276.5 13.2 2.3e-82 276.3 13.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP02040.1 - 2.1e-10 40.5 11.9 1.8e-09 37.4 11.9 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP02040.1 - 4.2e-07 30.0 9.4 2.5e-05 24.2 5.4 2.2 2 0 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP02040.1 - 9.1e-07 28.8 8.1 9.1e-07 28.8 8.1 2.2 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF1761 PF08570.10 KFP02040.1 - 0.36 11.1 9.9 0.59 10.4 0.1 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1761) Mei4 PF13971.6 KFP02042.1 - 5.5e-75 253.0 10.2 6.3e-75 252.8 10.2 1.0 1 0 0 1 1 1 1 Meiosis-specific protein Mei4 Bromodomain PF00439.25 KFP02043.1 - 2.4e-37 126.9 2.6 3.3e-18 65.5 0.0 3.0 3 0 0 3 3 3 2 Bromodomain WD40 PF00400.32 KFP02043.1 - 3.2e-33 113.2 15.1 3.2e-05 24.6 0.1 8.8 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP02043.1 - 0.00046 20.4 0.2 0.49 10.7 0.1 4.3 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain HMG14_17 PF01101.18 KFP02044.1 - 1.6e-21 77.1 22.4 1.7e-21 77.0 22.4 1.0 1 0 0 1 1 1 1 HMG14 and HMG17 TT_ORF2 PF02957.15 KFP02044.1 - 0.13 13.2 9.9 0.15 13.0 9.9 1.0 1 0 0 1 1 1 0 TT viral ORF2 DUF2477 PF10631.9 KFP02044.1 - 0.33 11.6 3.3 0.35 11.5 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) Lebercilin PF15619.6 KFP02045.1 - 4.5e-69 232.0 54.1 4.5e-69 232.0 54.1 2.3 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease IFT57 PF10498.9 KFP02045.1 - 0.3 10.0 33.1 1.2 8.0 12.6 2.6 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Golgin_A5 PF09787.9 KFP02045.1 - 6.9 6.0 49.9 0.58 9.6 16.0 3.1 2 1 1 3 3 3 0 Golgin subfamily A member 5 ELO PF01151.18 KFP02046.1 - 2.2e-64 217.4 25.2 2.6e-64 217.1 25.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Pkinase PF00069.25 KFP02047.1 - 2.4e-64 217.2 0.9 5.4e-64 216.1 0.9 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP02047.1 - 5.8e-33 114.3 0.1 1e-32 113.5 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP02047.1 - 2.8e-08 33.4 2.1 1e-05 25.0 0.0 3.4 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 KFP02047.1 - 1e-05 25.6 0.0 0.18 11.7 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family FTA2 PF13095.6 KFP02047.1 - 5.7e-05 22.8 0.1 0.36 10.4 0.0 2.6 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KFP02047.1 - 0.00019 20.9 0.0 0.0004 19.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFP02047.1 - 0.0012 18.5 2.8 0.0095 15.5 0.4 2.3 1 1 1 2 2 2 1 RIO1 family Mad3_BUB1_I_2 PF17014.5 KFP02047.1 - 0.0028 17.8 0.2 0.0098 16.0 0.2 1.9 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Tubulin PF00091.25 KFP02047.1 - 0.0056 16.9 0.2 0.051 13.8 0.0 2.3 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Mad3_BUB1_I PF08311.12 KFP02047.1 - 0.0066 16.4 0.0 0.023 14.7 0.0 2.0 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Kinase-PolyVal PF18762.1 KFP02047.1 - 0.017 15.1 1.0 0.046 13.7 1.0 1.7 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Transket_pyr PF02779.24 KFP02048.1 - 3.7e-43 147.3 0.0 4.8e-43 146.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFP02048.1 - 8.4e-36 122.6 0.0 1.8e-35 121.6 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Yae1_N PF09811.9 KFP02049.1 - 7.7e-18 63.9 63.5 1.8e+04 -28.3 63.5 6.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal NTP_transf_7 PF07984.12 KFP02050.1 - 1.3e-108 363.1 1.2 1.5e-108 362.9 1.2 1.0 1 0 0 1 1 1 1 Nucleotidyltransferase BTB PF00651.31 KFP02051.1 - 2.4e-30 105.0 6.2 3.5e-15 56.2 1.2 3.0 2 1 1 3 3 3 2 BTB/POZ domain RCC1 PF00415.18 KFP02051.1 - 7.1e-30 103.4 16.6 8.2e-11 42.4 1.9 5.0 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Ank_5 PF13857.6 KFP02051.1 - 1.1e-11 44.7 0.0 8.3e-06 26.0 0.0 3.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP02051.1 - 1.5e-08 35.1 0.0 4.9e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) RCC1_2 PF13540.6 KFP02051.1 - 2e-08 33.8 17.3 6.1e-05 22.7 0.0 5.8 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 KFP02051.1 - 2.5e-08 34.3 0.0 2.6e-05 24.7 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP02051.1 - 0.00017 21.8 0.0 1.8 9.3 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KFP02051.1 - 0.0003 21.1 0.0 0.29 11.7 0.0 3.2 2 0 0 2 2 2 1 Ankyrin repeat Bcr-Abl_Oligo PF09036.10 KFP02051.1 - 0.04 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain DUF1265 PF06887.14 KFP02051.1 - 0.12 12.3 0.5 0.34 10.9 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1265) SUKH-3 PF14433.6 KFP02051.1 - 0.17 12.4 0.1 52 4.3 0.0 3.9 4 1 1 5 5 5 0 SUKH-3 immunity protein HECT_2 PF09814.9 KFP02053.1 - 3.8e-68 230.1 0.9 4.5e-68 229.8 0.9 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Dopey_N PF04118.14 KFP02054.1 - 1.8e-106 355.7 0.2 1.2e-105 353.0 0.1 2.5 2 0 0 2 2 2 1 Dopey, N-terminal PGM_PMM_I PF02878.16 KFP02055.1 - 5.2e-19 68.3 0.1 9.7e-08 31.8 0.0 3.4 2 2 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KFP02055.1 - 3.7e-11 43.0 0.3 3.7e-11 43.0 0.3 2.6 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 KFP02055.1 - 0.00028 21.0 0.5 0.00094 19.4 0.5 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III CinA_KH PF18146.1 KFP02055.1 - 0.029 14.5 0.5 3.5 7.9 0.0 2.8 2 0 0 2 2 2 0 Damage-inducible protein CinA KH domain DUF4385 PF14328.6 KFP02055.1 - 0.14 12.2 0.1 18 5.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4385) DUF1115 PF06544.12 KFP02056.1 - 3.4e-14 53.2 0.3 1.6e-13 51.0 0.1 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1115) RWD PF05773.22 KFP02056.1 - 9e-14 51.7 0.0 1.8e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 RWD domain THDPS_N_2 PF14805.6 KFP02056.1 - 0.039 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Herpes_US9 PF06072.11 KFP02056.1 - 0.091 12.6 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 SAUGI PF06106.11 KFP02056.1 - 0.093 13.2 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 S. aureus uracil DNA glycosylase inhibitor Acylphosphatase PF00708.18 KFP02056.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Acylphosphatase Malic_M PF03949.15 KFP02057.1 - 7.5e-81 271.2 0.4 1.7e-80 270.0 0.4 1.6 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KFP02057.1 - 3.1e-80 268.2 0.0 5.1e-80 267.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Trypsin PF00089.26 KFP02058.1 - 4.5e-11 43.0 0.0 4e-09 36.6 0.0 2.5 3 0 0 3 3 3 1 Trypsin Trypsin_2 PF13365.6 KFP02058.1 - 5.7e-06 27.3 0.0 1.2e-05 26.2 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 KFP02058.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 LAP1C PF05609.12 KFP02058.1 - 0.16 11.1 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) ANTH PF07651.16 KFP02059.1 - 6.5e-85 284.5 0.5 7.8e-85 284.2 0.5 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KFP02059.1 - 7.2e-15 55.1 0.0 1.2e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 ENTH domain VHS PF00790.19 KFP02059.1 - 0.055 13.3 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 VHS domain Ripply PF14998.6 KFP02060.1 - 1.6e-29 102.4 0.2 2e-29 102.1 0.2 1.1 1 0 0 1 1 1 1 Transcription Regulator Cyt-b5 PF00173.28 KFP02061.1 - 5.4e-24 84.1 0.0 1.4e-23 82.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.21 KFP02061.1 - 5.4e-18 65.6 0.0 1.9e-17 63.9 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KFP02061.1 - 2e-17 63.4 0.0 7e-17 61.6 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain CS PF04969.16 KFP02061.1 - 3.4e-08 34.4 0.3 9.5e-08 33.0 0.3 1.8 1 0 0 1 1 1 1 CS domain NAD_binding_6 PF08030.12 KFP02061.1 - 3.7e-05 23.9 0.0 0.0023 18.1 0.0 2.5 1 1 1 2 2 2 1 Ferric reductase NAD binding domain DUF3858 PF12970.7 KFP02061.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3858) MRAP PF15183.6 KFP02062.1 - 2.2e-34 117.3 0.1 3.3e-34 116.7 0.1 1.2 1 0 0 1 1 1 1 Melanocortin-2 receptor accessory protein family WD40_4 PF16300.5 KFP02062.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Type of WD40 repeat DUF2553 PF10830.8 KFP02063.1 - 0.11 13.4 2.6 0.82 10.5 2.6 2.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2553) VGPC1_C PF16799.5 KFP02063.1 - 2.8 8.0 26.1 0.76 9.8 1.7 5.3 3 1 1 4 4 4 0 C-terminal membrane-localisation domain of ion-channel, VCN1 GPHR_N PF12537.8 KFP02063.1 - 3.5 7.8 7.4 3 8.0 0.0 4.8 5 0 0 5 5 5 0 The Golgi pH Regulator (GPHR) Family N-terminal T-box PF00907.22 KFP02064.1 - 1.2e-80 270.1 0.0 1.4e-80 269.9 0.0 1.0 1 0 0 1 1 1 1 T-box Glyco_hydro_36C PF16874.5 KFP02064.1 - 0.14 12.6 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 36 C-terminal domain Pkinase PF00069.25 KFP02065.1 - 2.6e-73 246.7 0.0 3.1e-73 246.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP02065.1 - 1.1e-42 146.2 0.0 1.5e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP02065.1 - 1.2e-11 44.5 0.1 3.2e-10 39.8 0.0 2.0 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFP02065.1 - 2.5e-05 23.7 0.1 4.7e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFP02065.1 - 0.0001 21.4 0.3 0.00014 20.9 0.3 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KFP02065.1 - 0.00048 19.8 0.3 0.00085 19.0 0.4 1.5 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 KFP02065.1 - 0.0012 18.8 0.2 0.0024 17.8 0.2 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KFP02065.1 - 0.04 13.5 0.1 0.086 12.5 0.1 1.4 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 WaaY PF06176.11 KFP02065.1 - 0.078 12.6 0.9 0.38 10.3 0.9 1.9 1 1 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) 5_nucleotid_C PF02872.18 KFP02066.1 - 1.7e-40 138.8 0.0 3e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KFP02066.1 - 0.0004 20.9 0.0 0.00076 20.0 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PXA PF02194.15 KFP02067.1 - 1.1e-37 129.7 0.5 3.3e-37 128.2 0.5 1.8 1 0 0 1 1 1 1 PXA domain PX PF00787.24 KFP02067.1 - 2.2e-20 72.7 1.1 2.2e-20 72.7 1.1 2.7 3 0 0 3 3 3 1 PX domain Nexin_C PF08628.12 KFP02067.1 - 7.4e-15 55.5 0.0 2.5e-14 53.8 0.0 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal RGS PF00615.19 KFP02067.1 - 1.4e-12 47.9 2.0 3.2e-12 46.8 1.1 2.2 2 0 0 2 2 2 1 Regulator of G protein signaling domain dDENN PF03455.19 KFP02067.1 - 0.16 12.0 3.5 3.7 7.6 0.4 3.9 4 0 0 4 4 4 0 dDENN domain RRM_1 PF00076.22 KFP02068.1 - 2e-45 152.5 1.3 8.6e-16 57.5 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) hnRNP_Q_AcD PF18360.1 KFP02068.1 - 3.2e-33 113.5 0.3 1.9e-32 111.0 0.1 2.2 2 0 0 2 2 2 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain RRM_5 PF13893.6 KFP02068.1 - 6.3e-07 29.0 0.0 0.00027 20.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP02068.1 - 3e-06 27.2 0.3 0.92 9.7 0.0 4.3 3 2 0 3 3 3 2 RNA recognition motif Limkain-b1 PF11608.8 KFP02068.1 - 7.7e-05 22.7 0.1 0.31 11.1 0.1 3.6 3 1 0 3 3 3 2 Limkain b1 RRM_occluded PF16842.5 KFP02068.1 - 0.0039 17.0 0.1 0.081 12.8 0.0 2.9 3 0 0 3 3 3 1 Occluded RNA-recognition motif Calcipressin PF04847.12 KFP02068.1 - 0.019 14.7 0.1 0.14 11.9 0.3 2.3 3 0 0 3 3 3 0 Calcipressin PHM7_cyt PF14703.6 KFP02068.1 - 0.02 15.1 2.4 7.5 6.8 0.1 4.3 3 2 0 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter Yae1_N PF09811.9 KFP02069.1 - 2.5e-16 59.1 57.0 1.8e+04 -21.9 57.0 5.4 1 1 0 1 1 1 0 Essential protein Yae1, N terminal 7tm_1 PF00001.21 KFP02070.1 - 7.4e-74 248.4 10.2 9.6e-74 248.0 10.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP02070.1 - 3.9e-08 33.3 14.6 7.4e-08 32.3 14.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFP02070.1 - 5.6e-07 29.2 12.1 1.1e-06 28.3 12.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP02070.1 - 2.8e-05 24.0 12.4 0.0003 20.6 12.4 2.1 1 1 0 1 1 1 1 Olfactory receptor Hormone_6 PF00236.18 KFP02071.1 - 6.7e-53 176.7 8.9 8e-53 176.4 8.9 1.1 1 0 0 1 1 1 1 Glycoprotein hormone PDGF PF00341.17 KFP02071.1 - 0.07 13.4 8.9 0.13 12.6 8.9 1.5 1 1 0 1 1 1 0 PDGF/VEGF domain zf-C2H2 PF00096.26 KFP02072.1 - 2.7e-14 52.7 99.8 0.012 16.0 1.5 16.0 16 0 0 16 16 16 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP02072.1 - 2.3e-11 43.5 99.7 0.22 12.5 2.3 16.0 16 0 0 16 16 16 10 C2H2-type zinc finger zinc_ribbon_11 PF11682.8 KFP02072.1 - 0.0031 17.5 0.2 0.022 14.8 0.2 2.5 1 0 0 1 1 1 1 Probable zinc-ribbon FOXP-CC PF16159.5 KFP02072.1 - 0.054 14.1 44.4 2.7 8.7 0.7 12.2 9 2 4 13 13 13 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 KFP02072.1 - 0.17 11.7 8.5 2 8.2 0.1 4.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Zn_ribbon_SprT PF17283.2 KFP02072.1 - 0.3 11.0 5.4 0.76 9.7 1.7 3.0 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Zn-C2H2_12 PF18112.1 KFP02072.1 - 0.36 11.3 7.1 12 6.4 0.7 3.4 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf_Hakai PF18408.1 KFP02072.1 - 0.51 10.1 25.3 0.56 10.0 0.1 6.3 6 0 0 6 6 6 0 C2H2 Hakai zinc finger domain zf-C2H2_8 PF15909.5 KFP02072.1 - 0.59 10.5 54.3 1.8 8.9 0.8 10.7 9 3 3 12 12 12 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 KFP02072.1 - 0.61 10.1 48.1 0.26 11.3 0.6 8.8 10 0 0 10 10 9 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KFP02072.1 - 1.3 8.7 6.2 0.6 9.8 0.1 3.7 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Connexin PF00029.19 KFP02073.1 - 3.3e-80 269.2 8.4 2.8e-45 154.9 0.7 2.0 1 1 1 2 2 2 2 Connexin Lustrin_cystein PF14625.6 KFP02073.1 - 0.038 14.4 1.1 0.31 11.4 0.1 2.2 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain Yae1_N PF09811.9 KFP02074.1 - 1.9e-13 49.9 50.6 1.8e+04 -15.8 50.4 5.3 1 1 0 1 1 1 0 Essential protein Yae1, N terminal FAP206 PF12018.8 KFP02075.1 - 7.7e-98 327.4 6.0 1.7e-97 326.3 6.0 1.6 1 0 0 1 1 1 1 Domain of unknown function HpaP PF09483.10 KFP02075.1 - 0.024 14.9 0.1 0.073 13.3 0.1 1.8 1 0 0 1 1 1 0 Type III secretion protein (HpaP) ATP-synt_D PF01813.17 KFP02075.1 - 0.084 12.7 1.7 1.8 8.3 0.2 3.4 3 1 1 4 4 4 0 ATP synthase subunit D THP2 PF09432.10 KFP02075.1 - 0.1 12.7 3.2 0.66 10.0 0.1 2.7 2 0 0 2 2 2 0 Tho complex subunit THP2 PMD PF10536.9 KFP02075.1 - 0.12 11.5 1.6 0.12 11.5 0.2 1.6 2 0 0 2 2 2 0 Plant mobile domain Nuc_sug_transp PF04142.15 KFP02076.1 - 3e-120 401.1 28.1 3.5e-120 400.9 28.1 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KFP02076.1 - 0.001 19.3 33.1 0.24 11.5 16.8 3.0 2 1 0 2 2 2 2 EamA-like transporter family Phage_holin_3_5 PF16085.5 KFP02076.1 - 1.1 9.4 7.3 0.74 10.0 2.8 2.6 2 0 0 2 2 2 0 Bacteriophage holin Hol, superfamily III tRNA-synt_1d PF00750.19 KFP02077.1 - 1.8e-88 296.9 2.1 2.3e-88 296.5 2.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KFP02077.1 - 6.8e-21 74.7 2.6 7.2e-21 74.6 0.3 2.3 3 0 0 3 3 3 1 DALR anticodon binding domain tRNA-synt_1g PF09334.11 KFP02077.1 - 0.029 13.1 0.6 1.1 7.9 0.1 2.4 1 1 1 2 2 2 0 tRNA synthetases class I (M) GDH_N PF12466.8 KFP02077.1 - 0.06 13.6 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal ORC3_N PF07034.11 KFP02078.1 - 3.5e-127 424.1 4.3 8.5e-127 422.8 4.3 1.6 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 KFP02078.1 - 1.3e-30 106.3 0.0 8.5e-29 100.4 0.0 2.8 1 1 0 1 1 1 1 Origin recognition complex winged helix C-terminal EF-G-binding_N PF07299.11 KFP02078.1 - 0.82 10.2 5.1 7.9 7.1 0.1 3.9 3 0 0 3 3 3 0 Elongation factor G-binding protein, N-terminal TAFH PF07531.14 KFP02078.1 - 3.8 7.7 9.8 2.4 8.3 0.1 4.3 5 0 0 5 5 5 0 NHR1 homology to TAF PET10 PF17316.2 KFP02079.1 - 0.032 13.7 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 Petite colonies protein 10 Gelsolin PF00626.22 KFP02080.1 - 0.00073 19.4 0.1 0.0048 16.8 0.0 2.2 3 0 0 3 3 3 1 Gelsolin repeat Sec23_helical PF04815.15 KFP02080.1 - 0.022 14.6 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Sec23/Sec24 helical domain RAMP4 PF06624.12 KFP02081.1 - 0.011 15.7 0.1 0.018 15.1 0.1 1.4 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 DUF5383 PF17355.2 KFP02081.1 - 0.017 15.5 0.1 0.021 15.2 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5383) TMEM223 PF14640.6 KFP02081.1 - 0.021 15.0 0.1 0.033 14.4 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 223 DUF930 PF06059.12 KFP02081.1 - 0.027 15.0 0.1 0.032 14.8 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF930) DUF5305 PF17231.2 KFP02081.1 - 0.04 13.3 0.4 0.052 12.9 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) EssA PF10661.9 KFP02081.1 - 0.043 13.7 0.3 0.049 13.5 0.3 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA Peptidase_M56 PF05569.11 KFP02081.1 - 0.057 12.6 0.1 0.057 12.6 0.1 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF2207 PF09972.9 KFP02081.1 - 0.066 12.0 0.0 0.066 12.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4366 PF14283.6 KFP02081.1 - 0.1 12.6 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Orf78 PF06024.12 KFP02081.1 - 0.12 12.7 0.1 0.14 12.4 0.1 1.2 1 0 0 1 1 1 0 Orf78 (ac78) 7tm_1 PF00001.21 KFP02082.1 - 2.8e-45 154.7 16.7 4.2e-45 154.1 16.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP02082.1 - 1.9e-12 47.1 17.0 2.9e-12 46.5 17.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP02082.1 - 1e-09 38.6 13.5 3.2e-06 27.1 3.7 2.5 2 1 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP02082.1 - 4.3e-07 29.8 9.8 4.3e-07 29.8 9.8 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx YlaC PF10777.9 KFP02082.1 - 0.12 12.2 3.7 0.3 10.9 0.3 2.6 3 0 0 3 3 3 0 Inner membrane protein YlaC mRNA_cap_enzyme PF01331.19 KFP02083.1 - 7.1e-76 254.4 0.1 1e-75 253.9 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KFP02083.1 - 5.9e-20 71.9 0.0 1.2e-19 71.0 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DSPc PF00782.20 KFP02083.1 - 1.1e-10 41.4 0.0 2.6e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DNA_ligase_A_M PF01068.21 KFP02083.1 - 7.6e-06 25.7 0.0 0.0065 16.1 0.0 2.6 1 1 1 2 2 2 2 ATP dependent DNA ligase domain Y_phosphatase PF00102.27 KFP02083.1 - 0.00037 20.2 0.0 0.00061 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KFP02083.1 - 0.04 13.5 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KFP02083.1 - 0.16 12.0 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family PNRC PF15365.6 KFP02084.1 - 6.2e-07 29.0 6.9 6.2e-07 29.0 6.9 1.6 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator motif M20_dimer PF07687.14 KFP02085.1 - 7.3e-10 38.7 0.0 1.4e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KFP02085.1 - 0.00028 20.6 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 KfrB PF18790.1 KFP02085.1 - 0.14 12.4 0.2 0.45 10.8 0.0 1.9 2 0 0 2 2 2 0 KfrB protein Neur_chan_LBD PF02931.23 KFP02086.1 - 9.5e-52 175.6 0.6 1.4e-51 175.1 0.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP02086.1 - 1.1e-35 123.8 6.2 1.3e-30 107.3 3.7 2.3 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_memb PF02932.16 KFP02087.1 - 2.5e-36 125.9 5.1 1.1e-32 114.0 1.9 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFP02087.1 - 3.5e-32 111.6 0.7 2.4e-31 108.9 0.7 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Gtr1_RagA PF04670.12 KFP02088.1 - 4.7e-73 245.4 0.7 6.6e-73 244.9 0.7 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KFP02088.1 - 9.2e-07 28.5 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFP02088.1 - 1.4e-05 24.6 0.1 3.2e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KFP02088.1 - 2.5e-05 24.5 0.0 4.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP02088.1 - 0.0049 16.5 0.0 0.0077 15.8 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KFP02088.1 - 0.0082 16.2 0.0 0.025 14.7 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFP02088.1 - 0.15 12.4 0.0 0.35 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Ank_2 PF12796.7 KFP02089.1 - 8.8e-41 138.4 14.6 1.8e-10 41.3 0.1 4.6 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP02089.1 - 2.3e-38 130.1 19.2 9.8e-10 38.8 0.3 6.4 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP02089.1 - 3.2e-37 126.1 12.3 3.3e-10 40.0 0.1 5.7 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KFP02089.1 - 2.1e-36 122.8 21.2 7.8e-08 32.4 0.7 7.8 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 KFP02089.1 - 2.8e-31 104.1 9.2 1.4e-05 25.0 0.1 8.2 8 0 0 8 8 8 6 Ankyrin repeat Phasin PF05597.11 KFP02089.1 - 0.048 13.7 6.5 0.64 10.0 0.8 3.2 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) EccE PF11203.8 KFP02089.1 - 0.059 13.7 4.4 4.3 7.7 0.4 3.1 2 1 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE DUF5320 PF17253.2 KFP02089.1 - 0.37 11.9 2.1 1.4 10.1 2.1 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5320) CLZ PF16526.5 KFP02089.1 - 6.2 7.3 13.5 2.1 8.8 2.5 3.2 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Complex1_LYR PF05347.15 KFP02090.1 - 6e-20 71.1 0.8 7.3e-20 70.8 0.8 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFP02090.1 - 1.4e-08 35.4 1.2 1.8e-08 35.0 1.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KFP02090.1 - 6.4e-06 26.7 0.6 8.5e-06 26.3 0.5 1.2 1 1 0 1 1 1 1 Complex1_LYR-like ETC_C1_NDUFA5 PF04716.14 KFP02090.1 - 0.028 14.2 0.3 0.081 12.7 0.3 1.8 1 1 0 1 1 1 0 ETC complex I subunit conserved region AAA_5 PF07728.14 KFP02091.1 - 9.9e-123 404.6 0.0 6.3e-25 87.8 0.0 8.9 7 1 0 8 8 8 8 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KFP02091.1 - 1.5e-64 214.8 4.3 5.9e-26 90.7 0.1 6.7 6 0 0 6 6 6 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 KFP02091.1 - 1.6e-33 115.0 0.3 2.7e-32 111.0 0.0 3.2 3 0 0 3 3 2 1 Midasin AAA lid domain AAA PF00004.29 KFP02091.1 - 1.2e-24 87.3 0.4 0.00077 19.9 0.1 7.2 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 KFP02091.1 - 4.9e-23 81.4 0.0 1.7e-07 31.1 0.0 7.2 7 0 0 7 7 7 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KFP02091.1 - 2.4e-21 76.0 3.4 0.00095 18.7 0.0 6.7 6 0 0 6 6 6 4 P-loop containing dynein motor region AAA_16 PF13191.6 KFP02091.1 - 8.5e-21 75.1 26.6 0.00069 20.0 0.1 9.6 10 2 0 10 10 7 6 AAA ATPase domain Dynein_heavy PF03028.15 KFP02091.1 - 3.8e-17 62.5 0.0 0.00071 19.7 0.0 7.9 9 0 0 9 9 6 3 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 KFP02091.1 - 5.5e-17 62.3 2.9 0.0028 17.9 0.0 8.2 7 0 0 7 7 7 4 AAA domain AAA_18 PF13238.6 KFP02091.1 - 2.5e-16 60.4 4.1 0.28 11.7 0.0 8.8 7 0 0 7 7 7 4 AAA domain TsaE PF02367.17 KFP02091.1 - 3.1e-15 56.3 4.5 0.21 11.6 0.1 6.9 6 0 0 6 6 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KFP02091.1 - 4.1e-15 56.0 0.0 0.015 15.4 0.0 7.4 6 1 1 7 7 7 3 AAA domain ABC_tran PF00005.27 KFP02091.1 - 3e-14 53.7 6.8 0.0072 16.8 0.0 7.7 7 0 0 7 7 6 2 ABC transporter Sigma54_activat PF00158.26 KFP02091.1 - 1.4e-13 50.9 1.3 0.45 10.2 0.0 7.1 7 0 0 7 7 7 3 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 KFP02091.1 - 3.1e-12 46.8 1.1 0.00051 20.2 0.0 6.5 7 0 0 7 7 5 2 Sigma-54 interaction domain AAA_6 PF12774.7 KFP02091.1 - 6.2e-11 41.8 2.3 0.086 11.8 0.0 6.9 8 0 0 8 8 6 2 Hydrolytic ATP binding site of dynein motor region RsgA_GTPase PF03193.16 KFP02091.1 - 1.2e-10 41.5 5.9 0.35 10.8 0.0 6.8 6 0 0 6 6 6 2 RsgA GTPase NACHT PF05729.12 KFP02091.1 - 3.4e-09 36.8 4.1 1.6 8.7 0.0 7.1 6 0 0 6 6 6 1 NACHT domain AAA_30 PF13604.6 KFP02091.1 - 1.6e-08 34.5 1.2 2.5 7.8 0.0 6.5 6 1 0 6 6 6 1 AAA domain Roc PF08477.13 KFP02091.1 - 2.3e-08 34.2 1.6 3.9 7.7 0.0 6.5 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase Mg_chelatase PF01078.21 KFP02091.1 - 3.5e-08 33.1 7.7 4 6.8 0.0 8.0 6 2 1 7 7 7 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KFP02091.1 - 5.3e-08 33.1 1.9 0.27 11.4 0.0 6.3 6 0 0 6 6 5 1 AAA domain RNA_helicase PF00910.22 KFP02091.1 - 5.7e-08 33.1 0.4 5.5 7.4 0.0 6.6 6 0 0 6 6 6 0 RNA helicase DUF815 PF05673.13 KFP02091.1 - 9.1e-08 31.6 2.2 0.084 12.0 0.0 5.6 6 0 0 6 6 6 2 Protein of unknown function (DUF815) Rad17 PF03215.15 KFP02091.1 - 5.7e-07 29.6 1.3 8.4 6.3 0.0 5.9 5 0 0 5 5 5 0 Rad17 P-loop domain PduV-EutP PF10662.9 KFP02091.1 - 6.2e-07 29.3 3.1 0.23 11.2 0.1 5.8 6 0 0 6 6 5 1 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 KFP02091.1 - 1.3e-06 28.0 0.9 4.8 7.0 0.0 6.3 6 0 0 6 6 6 0 P-loop containing region of AAA domain AAA_8 PF12780.7 KFP02091.1 - 2e-06 27.3 2.5 0.3 10.4 0.0 5.7 6 0 0 6 6 6 1 P-loop containing dynein motor region D4 RuvB_N PF05496.12 KFP02091.1 - 2.2e-06 27.5 6.3 4.3 7.0 0.0 6.8 7 0 0 7 7 7 0 Holliday junction DNA helicase RuvB P-loop domain SRP54 PF00448.22 KFP02091.1 - 2.5e-06 27.2 2.3 2.9 7.5 0.0 5.2 5 0 0 5 5 5 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 KFP02091.1 - 6.4e-06 26.6 2.6 1.6 9.0 0.0 5.8 5 0 0 5 5 4 1 AAA domain AAA_25 PF13481.6 KFP02091.1 - 6.4e-06 25.9 10.7 0.98 9.0 0.0 6.5 7 0 0 7 7 6 2 AAA domain Zeta_toxin PF06414.12 KFP02091.1 - 3e-05 23.4 1.1 8.1 5.7 0.0 5.7 6 0 0 6 6 6 0 Zeta toxin IstB_IS21 PF01695.17 KFP02091.1 - 4.1e-05 23.4 2.0 8.9 6.0 0.0 6.0 6 0 0 6 6 6 0 IstB-like ATP binding protein AAA_28 PF13521.6 KFP02091.1 - 7.1e-05 23.1 12.9 3.9 7.7 0.0 7.9 8 0 0 8 8 7 0 AAA domain MMR_HSR1 PF01926.23 KFP02091.1 - 8.3e-05 22.6 0.7 31 4.7 0.0 6.5 6 0 0 6 6 6 0 50S ribosome-binding GTPase SRPRB PF09439.10 KFP02091.1 - 0.00015 21.2 2.3 12 5.2 0.0 5.6 6 0 0 6 6 6 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 KFP02091.1 - 0.00034 20.4 4.0 17 5.0 0.0 6.2 7 0 0 7 7 5 0 AAA domain TniB PF05621.11 KFP02091.1 - 0.00074 19.0 0.2 0.77 9.1 0.0 4.7 6 0 0 6 6 5 1 Bacterial TniB protein DEAD PF00270.29 KFP02091.1 - 0.00074 19.3 0.1 5.4 6.8 0.0 4.2 4 0 0 4 4 4 0 DEAD/DEAH box helicase MCM PF00493.23 KFP02091.1 - 0.00082 18.5 0.2 0.41 9.7 0.0 4.2 5 0 0 5 5 4 1 MCM P-loop domain CPT PF07931.12 KFP02091.1 - 0.00093 19.1 3.3 18 5.1 0.0 5.7 7 0 0 7 7 5 0 Chloramphenicol phosphotransferase-like protein ATPase PF06745.13 KFP02091.1 - 0.0073 15.7 0.8 1.5 8.1 0.0 3.7 3 0 0 3 3 3 1 KaiC ATP-synt_ab PF00006.25 KFP02091.1 - 0.012 15.3 0.0 3 7.4 0.0 3.4 4 0 0 4 4 3 0 ATP synthase alpha/beta family, nucleotide-binding domain dNK PF01712.19 KFP02091.1 - 0.04 13.8 6.9 2.9 7.7 0.0 5.5 6 0 0 6 6 5 0 Deoxynucleoside kinase CbiA PF01656.23 KFP02091.1 - 0.1 12.7 2.2 58 3.7 0.1 5.1 6 0 0 6 6 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 KFP02091.1 - 0.49 10.1 4.5 67 3.2 0.1 4.8 5 0 0 5 5 4 0 Conserved hypothetical ATP binding protein cobW PF02492.19 KFP02091.1 - 0.9 9.1 5.3 37 3.9 0.0 4.4 5 0 0 5 5 5 0 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.22 KFP02091.1 - 1.1 8.9 6.5 23 4.6 0.0 4.7 5 0 0 5 5 5 0 Ras family AAA_21 PF13304.6 KFP02091.1 - 4.8 6.9 6.6 24 4.6 0.0 4.0 4 0 0 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system F_actin_bind PF08919.10 KFP02091.1 - 5.4 7.1 6.4 9.8 6.3 0.1 4.7 4 0 0 4 4 2 0 F-actin binding Connexin PF00029.19 KFP02092.1 - 2.1e-89 299.3 0.2 2.3e-89 299.2 0.2 1.0 1 0 0 1 1 1 1 Connexin BTB PF00651.31 KFP02093.1 - 3.8e-28 97.9 0.3 6.4e-28 97.2 0.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain bZIP_Maf PF03131.17 KFP02093.1 - 4.6e-13 49.5 2.5 1.1e-12 48.3 2.5 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 KFP02093.1 - 1.3e-09 38.0 6.7 2.4e-09 37.1 6.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFP02093.1 - 1.8e-05 24.7 7.5 3e-05 24.0 7.5 1.4 1 0 0 1 1 1 1 Basic region leucine zipper DUF3342 PF11822.8 KFP02093.1 - 0.038 14.2 0.0 0.15 12.3 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) Pkinase_Tyr PF07714.17 KFP02094.1 - 2.4e-60 204.0 0.0 3.9e-60 203.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP02094.1 - 1e-55 189.0 0.0 2.8e-55 187.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 KFP02094.1 - 0.0048 16.8 0.0 0.013 15.4 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Lectin_N PF03954.14 KFP02094.1 - 4 7.2 7.6 0.16 11.7 0.7 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF3432 PF11914.8 KFP02095.1 - 1.3e-33 115.1 39.2 1.3e-33 115.1 39.2 3.7 3 2 1 4 4 2 1 Domain of unknown function (DUF3432) DUF3446 PF11928.8 KFP02095.1 - 1.8e-26 92.3 16.5 1.8e-26 92.3 16.5 4.1 3 1 1 4 4 3 1 Early growth response N-terminal domain zf-H2C2_2 PF13465.6 KFP02095.1 - 1.3e-16 60.1 19.3 6.1e-08 32.8 0.8 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFP02095.1 - 3.6e-15 55.5 16.5 3.5e-05 24.0 0.3 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP02095.1 - 2.1e-11 43.6 12.8 0.0021 18.7 2.1 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP02095.1 - 0.00054 20.2 1.6 11 6.5 0.2 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFP02095.1 - 0.0021 17.9 8.9 0.2 11.6 0.5 3.4 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-BED PF02892.15 KFP02095.1 - 0.006 16.6 7.8 0.012 15.6 2.9 2.6 1 1 1 2 2 2 1 BED zinc finger Zf_RING PF16744.5 KFP02095.1 - 0.0063 16.6 1.6 0.26 11.4 0.1 2.3 1 1 1 2 2 2 1 KIAA1045 RING finger zf-C2H2_6 PF13912.6 KFP02095.1 - 0.019 15.0 4.5 7.8 6.6 0.5 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFP02095.1 - 0.23 11.3 6.9 26 4.7 0.1 3.8 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 KFP02095.1 - 1.2 9.6 4.7 23 5.5 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-CHY PF05495.12 KFP02095.1 - 1.6 9.3 4.7 8.6 6.9 4.8 2.0 1 1 0 1 1 1 0 CHY zinc finger DUF629 PF04780.12 KFP02095.1 - 4.8 5.6 4.5 11 4.3 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF629) TB2_DP1_HVA22 PF03134.19 KFP02096.1 - 3.1e-28 97.5 10.0 4.4e-28 97.0 10.0 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2306 PF10067.9 KFP02096.1 - 0.028 14.6 0.5 0.044 14.0 0.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) JmjC PF02373.22 KFP02097.1 - 8e-16 58.5 0.0 1.9e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KFP02097.1 - 0.12 12.1 0.1 0.45 10.3 0.0 1.9 2 0 0 2 2 2 0 Cupin domain C1_2 PF03107.16 KFP02097.1 - 0.12 12.7 4.9 0.42 11.0 4.9 2.0 1 0 0 1 1 1 0 C1 domain zf-C5HC2 PF02928.16 KFP02097.1 - 0.13 12.7 3.3 0.5 10.8 3.3 2.0 1 0 0 1 1 1 0 C5HC2 zinc finger 2-Hacid_dh_C PF02826.19 KFP02098.1 - 8.3e-57 191.4 0.0 1.2e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFP02098.1 - 4.4e-27 94.4 0.0 5.3e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFP02098.1 - 7.9e-05 22.9 0.0 0.00016 21.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 KFP02098.1 - 0.083 13.4 0.0 0.26 11.8 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain F420_oxidored PF03807.17 KFP02098.1 - 0.15 12.7 0.0 0.88 10.2 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent GDNF PF02351.16 KFP02099.1 - 3.7e-41 140.0 44.4 3.8e-23 82.3 9.3 3.1 3 0 0 3 3 3 3 GDNF/GAS1 domain TPR_1 PF00515.28 KFP02100.1 - 2.9e-27 93.3 38.1 6.7e-06 25.7 0.1 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 KFP02100.1 - 1.8e-25 87.0 38.1 0.00049 20.0 0.1 10.5 10 0 0 10 10 10 8 Tetratricopeptide repeat ANAPC8 PF04049.13 KFP02100.1 - 4.4e-24 85.1 7.6 1e-23 84.0 2.2 2.7 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.6 KFP02100.1 - 1.6e-19 68.4 30.9 7.9e-05 22.6 0.0 10.6 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFP02100.1 - 2.5e-14 52.8 19.7 0.0045 17.7 0.0 9.4 8 2 2 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFP02100.1 - 5.7e-13 49.2 20.6 0.0013 19.2 0.1 7.8 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFP02100.1 - 3e-09 37.4 14.2 0.0013 19.3 0.0 7.6 6 2 2 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFP02100.1 - 9.6e-09 34.7 21.9 0.091 12.8 0.2 8.6 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFP02100.1 - 1e-08 34.7 22.1 1.8e-06 27.5 0.2 5.9 5 1 1 6 6 6 3 TPR repeat ANAPC3 PF12895.7 KFP02100.1 - 4.4e-07 30.0 36.7 0.00045 20.4 0.9 6.4 5 1 2 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KFP02100.1 - 6.5e-07 29.3 17.0 0.098 13.1 0.0 6.8 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFP02100.1 - 8.3e-06 26.1 31.2 1.7 9.5 0.0 9.7 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFP02100.1 - 1.1e-05 25.6 29.7 0.28 11.5 0.1 8.7 5 2 4 9 9 9 3 Tetratricopeptide repeat DUF772 PF05598.11 KFP02100.1 - 0.009 16.0 0.1 0.025 14.6 0.1 1.8 1 0 0 1 1 1 1 Transposase domain (DUF772) TPR_10 PF13374.6 KFP02100.1 - 0.015 15.2 15.2 11 6.1 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFP02100.1 - 0.019 15.1 0.2 0.019 15.1 0.2 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 KFP02100.1 - 0.13 12.5 1.6 16 6.0 0.0 4.6 5 0 0 5 5 5 0 PPR repeat TPR_15 PF13429.6 KFP02100.1 - 0.24 10.6 10.3 0.1 11.8 1.7 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat JAKMIP_CC3 PF16034.5 KFP02101.1 - 7.7e-84 280.6 20.0 7.7e-84 280.6 20.0 6.7 3 2 3 6 6 6 1 JAKMIP CC3 domain Pox_A_type_inc PF04508.12 KFP02101.1 - 0.018 14.8 0.0 0.018 14.8 0.0 7.8 10 0 0 10 10 10 0 Viral A-type inclusion protein repeat Amidohydro_1 PF01979.20 KFP02102.1 - 5.9e-40 137.6 0.1 7.7e-40 137.2 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFP02102.1 - 6.8e-15 55.5 0.8 5e-07 29.6 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_2 PF04909.14 KFP02102.1 - 0.00089 19.1 0.0 0.0026 17.6 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase DUF3928 PF13065.6 KFP02102.1 - 0.14 12.9 0.0 0.28 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3928) Pkinase PF00069.25 KFP02103.1 - 4.2e-65 219.7 0.0 5.9e-65 219.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP02103.1 - 6e-39 133.9 0.0 7.8e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP02103.1 - 3.6e-13 49.5 0.1 4.7e-13 49.1 0.1 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFP02103.1 - 0.00075 18.5 0.4 0.0014 17.7 0.4 1.5 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFP02103.1 - 0.002 18.1 0.1 0.0028 17.6 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFP02103.1 - 0.0026 16.6 0.0 0.0046 15.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Endonuclease_5 PF04493.14 KFP02103.1 - 0.081 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Endonuclease V WD40 PF00400.32 KFP02104.1 - 3.4e-10 40.3 2.4 1.1 10.3 0.1 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP02104.1 - 0.00014 22.0 0.0 12 6.3 0.0 4.7 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 KFP02105.1 - 8.5e-10 38.3 0.6 0.00011 21.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFP02105.1 - 8.4e-09 35.3 0.0 0.00012 22.0 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 KFP02105.1 - 2.1e-05 24.4 0.6 0.098 12.6 0.0 3.1 2 2 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PWI PF01480.17 KFP02105.1 - 0.00013 22.2 0.0 0.00034 20.9 0.0 1.7 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.24 KFP02105.1 - 0.00014 21.6 1.1 0.00025 20.9 1.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF4840 PF16128.5 KFP02105.1 - 0.039 14.0 1.4 1.1 9.3 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4840) Herpes_UL6 PF01763.16 KFP02105.1 - 0.13 10.8 6.3 0.2 10.1 6.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like zf_CCCH_4 PF18345.1 KFP02105.1 - 0.17 12.0 0.6 0.29 11.3 0.6 1.4 1 0 0 1 1 1 0 Zinc finger domain FapA PF03961.13 KFP02105.1 - 0.36 9.4 11.2 0.63 8.6 11.2 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Ly49 PF08391.10 KFP02105.1 - 1.1 9.6 5.8 5.1 7.5 5.8 2.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region tRNA-synt_1 PF00133.22 KFP02106.1 - 7.5e-39 133.5 0.0 8.7e-25 87.0 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KFP02106.1 - 1.3e-18 66.9 0.0 2.4e-09 36.4 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KFP02106.1 - 8.9e-18 64.7 0.0 2.8e-17 63.1 0.0 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KFP02106.1 - 1.2e-06 28.1 0.0 2.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 KFP02106.1 - 0.025 13.5 0.4 0.076 11.9 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (K) DnaJ_CXXCXGXG PF00684.19 KFP02107.1 - 0.0083 16.5 10.3 0.015 15.6 9.8 1.7 1 1 1 2 2 2 2 DnaJ central domain DZR PF12773.7 KFP02107.1 - 4.1 7.5 15.8 14 5.8 0.0 3.1 2 1 0 2 2 2 0 Double zinc ribbon BTB_2 PF02214.22 KFP02108.1 - 4.4e-16 59.0 0.0 1.1e-15 57.8 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KFP02108.1 - 0.0056 16.8 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Yip1 PF04893.17 KFP02110.1 - 1.3e-09 38.0 16.7 1.8e-09 37.6 16.7 1.3 1 0 0 1 1 1 1 Yip1 domain DUF2374 PF09574.10 KFP02110.1 - 0.0076 16.1 1.3 0.022 14.6 1.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (Duf2374) GCR PF02155.15 KFP02111.1 - 1.4e-179 596.9 4.0 1.8e-179 596.6 4.0 1.1 1 0 0 1 1 1 1 Glucocorticoid receptor Hormone_recep PF00104.30 KFP02111.1 - 1.3e-29 103.3 5.2 1.3e-29 103.3 5.2 1.5 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFP02111.1 - 1.3e-23 83.2 15.8 8.6e-23 80.6 15.8 2.2 1 1 0 1 1 1 1 Zinc finger, C4 type (two domains) BAR_3 PF16746.5 KFP02112.1 - 9.9e-66 221.8 10.2 2e-65 220.8 10.2 1.5 1 0 0 1 1 1 1 BAR domain of APPL family RhoGAP PF00620.27 KFP02112.1 - 7.6e-41 139.5 1.4 2.1e-40 138.1 0.7 2.0 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 KFP02112.1 - 3.1e-10 40.5 0.2 1.5e-09 38.3 0.0 2.3 2 0 0 2 2 2 1 PH domain SH3_9 PF14604.6 KFP02112.1 - 3.8e-10 39.5 0.0 8.4e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP02112.1 - 4.4e-08 32.6 0.0 8.2e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP02112.1 - 7.6e-06 25.5 0.0 1.7e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain IMD PF08397.11 KFP02112.1 - 0.0068 15.8 5.2 0.0068 15.8 5.2 2.2 1 1 0 2 2 2 1 IRSp53/MIM homology domain Sld5 PF05916.11 KFP02112.1 - 5.5 7.5 7.0 5.1 7.6 0.7 3.3 3 1 1 4 4 4 0 GINS complex protein FGF PF00167.18 KFP02113.1 - 2.8e-41 140.5 0.0 3.3e-41 140.3 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.13 KFP02113.1 - 0.0032 17.7 0.0 0.005 17.0 0.0 1.3 1 0 0 1 1 1 1 Fascin domain DUF2370 PF10176.9 KFP02115.1 - 1.8e-06 27.8 5.6 0.00036 20.3 0.3 2.7 1 1 2 3 3 3 2 Protein of unknown function (DUF2370) Comm PF15957.5 KFP02115.1 - 0.017 15.4 0.1 0.032 14.6 0.1 1.5 1 0 0 1 1 1 0 Commissureless Herpes_UL56 PF04534.12 KFP02115.1 - 0.18 11.3 0.8 0.26 10.8 0.8 1.2 1 0 0 1 1 1 0 Herpesvirus UL56 protein WBP-1 PF11669.8 KFP02115.1 - 0.31 11.7 4.0 0.42 11.3 0.1 2.7 2 1 1 3 3 3 0 WW domain-binding protein 1 Phage_holin_3_6 PF07332.11 KFP02115.1 - 0.42 10.7 2.3 0.7 10.0 2.3 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III 2TM PF13239.6 KFP02115.1 - 4.8 7.6 11.6 0.2 11.9 4.6 1.9 2 0 0 2 2 2 0 2TM domain Glucosamine_iso PF01182.20 KFP02116.1 - 1.5e-12 47.9 0.0 2.5e-12 47.2 0.0 1.3 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase RWD PF05773.22 KFP02117.1 - 1.3e-25 89.9 0.0 2.6e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 RWD domain IBR PF01485.21 KFP02117.1 - 2.7e-17 62.7 23.5 5.5e-13 48.9 6.1 4.6 4 1 1 5 5 5 3 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 KFP02117.1 - 0.00034 20.5 13.3 0.00034 20.5 13.3 4.9 4 1 1 5 5 5 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFP02117.1 - 0.0025 18.1 10.3 0.0025 18.1 10.3 5.1 4 1 1 5 5 5 1 Ring finger domain DUF3644 PF12358.8 KFP02117.1 - 0.033 14.6 0.0 6.2 7.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3644) TBPIP PF07106.13 KFP02117.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain zf-RING_11 PF17123.5 KFP02117.1 - 0.47 10.3 12.1 0.66 9.8 7.6 3.5 2 0 0 2 2 2 0 RING-like zinc finger HSP70 PF00012.20 KFP02118.1 - 3.2e-184 613.5 10.2 1.4e-177 591.5 0.0 3.0 1 1 2 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 KFP02118.1 - 1.8e-07 30.3 0.0 0.00041 19.3 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Raco_middle PF17651.1 KFP02118.1 - 0.016 14.9 0.1 6.3 6.4 0.1 2.5 2 0 0 2 2 2 0 RACo middle region DUF853 PF05872.12 KFP02118.1 - 6 5.3 10.9 0.61 8.6 1.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) zf-CCHC_3 PF13917.6 KFP02119.1 - 1.1e-18 66.9 3.7 2.4e-18 65.8 3.7 1.6 1 0 0 1 1 1 1 Zinc knuckle CLIP1_ZNF PF16641.5 KFP02119.1 - 0.058 13.3 1.6 0.095 12.6 1.6 1.4 1 0 0 1 1 1 0 CLIP1 zinc knuckle Macoilin PF09726.9 KFP02119.1 - 1.1 7.7 31.6 1.5 7.3 31.6 1.3 1 0 0 1 1 1 0 Macoilin family Menin PF05053.13 KFP02119.1 - 1.6 7.0 17.0 2.1 6.6 17.0 1.2 1 0 0 1 1 1 0 Menin Rrn6 PF10214.9 KFP02119.1 - 2.1 6.8 34.1 2.2 6.7 34.1 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor PNISR PF15996.5 KFP02119.1 - 3.1 8.0 22.9 3.9 7.7 22.9 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR SPX PF03105.19 KFP02119.1 - 7.8 6.3 40.0 9 6.1 40.0 1.0 1 0 0 1 1 1 0 SPX domain AF-4 PF05110.13 KFP02120.1 - 0 1406.3 124.6 0 1406.2 124.6 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein LEAP-2 PF07359.11 KFP02121.1 - 6.7e-35 118.8 3.8 7.3e-35 118.6 3.8 1.0 1 0 0 1 1 1 1 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) EB PF01683.18 KFP02121.1 - 0.0027 18.0 0.3 0.0027 18.0 0.3 1.2 1 0 0 1 1 1 1 EB module UcrQ PF02939.16 KFP02122.1 - 1.8e-32 111.1 0.1 2e-32 111.0 0.1 1.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 KFP02122.1 - 0.0038 17.6 0.0 0.0043 17.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 TGF_beta PF00019.20 KFP02123.1 - 3.1e-26 92.4 0.3 6e-26 91.4 0.3 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFP02123.1 - 0.083 12.6 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 TGF-beta propeptide ASD1 PF08688.10 KFP02124.1 - 8.3e-38 130.5 12.4 8.6e-38 130.5 7.1 2.2 2 1 0 2 2 2 2 Apx/Shroom domain ASD1 ASD2 PF08687.11 KFP02125.1 - 9.9e-78 261.6 17.8 1.1e-77 261.5 17.8 1.0 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 DUF2721 PF11026.8 KFP02125.1 - 0.017 15.0 1.1 0.039 13.9 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF5320 PF17253.2 KFP02125.1 - 0.14 13.3 3.7 2.8 9.0 0.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Septin PF00735.18 KFP02126.1 - 4.9e-99 331.2 2.1 4.9e-99 331.2 2.1 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KFP02126.1 - 1.9e-06 27.9 0.6 4.5e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP02126.1 - 1.3e-05 25.1 4.3 0.0032 17.4 0.0 3.7 3 1 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 KFP02126.1 - 2.6e-05 23.8 3.5 0.57 9.7 0.3 3.3 3 0 0 3 3 3 3 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KFP02126.1 - 0.00021 21.6 0.1 0.00078 19.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 KFP02126.1 - 0.00037 20.7 0.0 0.0012 19.1 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KFP02126.1 - 0.00043 20.7 0.1 0.0016 18.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 KFP02126.1 - 0.003 18.1 1.5 0.024 15.2 0.1 2.5 2 1 0 2 2 2 1 ABC transporter Ras PF00071.22 KFP02126.1 - 0.0044 16.6 0.4 0.015 14.9 0.0 2.1 2 0 0 2 2 2 1 Ras family AAA_7 PF12775.7 KFP02126.1 - 0.0075 15.8 0.0 0.019 14.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region SWI-SNF_Ssr4 PF08549.10 KFP02126.1 - 0.018 13.7 4.4 0.026 13.2 4.4 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) AIG1 PF04548.16 KFP02126.1 - 0.026 13.8 5.5 0.066 12.5 0.0 2.5 2 0 0 2 2 2 0 AIG1 family Atg14 PF10186.9 KFP02126.1 - 0.043 12.9 10.5 0.11 11.6 10.5 1.7 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RNA_helicase PF00910.22 KFP02126.1 - 0.043 14.2 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Microtub_bd PF16796.5 KFP02126.1 - 0.074 13.0 0.0 0.074 13.0 0.0 2.7 2 1 0 2 2 2 0 Microtubule binding AAA_24 PF13479.6 KFP02126.1 - 0.089 12.5 1.0 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KFP02126.1 - 0.13 12.3 7.2 2.7 8.0 0.1 3.1 2 1 0 2 2 2 0 Dynamin family DUF87 PF01935.17 KFP02126.1 - 0.16 12.0 5.3 0.92 9.6 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_29 PF13555.6 KFP02126.1 - 0.17 11.7 0.1 0.46 10.3 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KFP02126.1 - 0.17 12.3 17.1 0.71 10.3 0.6 2.4 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 KFP02126.1 - 0.19 10.7 0.0 0.19 10.7 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein IMD PF08397.11 KFP02126.1 - 0.34 10.3 11.5 0.66 9.3 11.5 1.4 1 0 0 1 1 1 0 IRSp53/MIM homology domain Fzo_mitofusin PF04799.13 KFP02126.1 - 0.54 9.8 9.2 0.38 10.3 7.1 1.8 2 0 0 2 2 2 0 fzo-like conserved region Exonuc_VII_L PF02601.15 KFP02126.1 - 2.3 7.7 9.3 4.2 6.8 9.3 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP_bind_1 PF03029.17 KFP02126.1 - 3.8 7.2 7.9 22 4.7 0.1 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_11 PF13086.6 KFP02126.1 - 7.8 6.2 9.9 14 5.4 9.9 1.4 1 0 0 1 1 1 0 AAA domain Kinesin PF00225.23 KFP02127.1 - 1.7e-108 362.5 0.0 1.7e-108 362.5 0.0 1.7 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFP02127.1 - 6.3e-27 94.4 0.1 4e-26 91.7 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding CheZ PF04344.13 KFP02127.1 - 0.0037 17.2 6.5 0.0037 17.2 6.5 2.3 2 0 0 2 2 2 1 Chemotaxis phosphatase, CheZ PIF1 PF05970.14 KFP02127.1 - 0.019 14.2 0.4 0.047 12.8 0.0 1.7 2 0 0 2 2 2 0 PIF1-like helicase AAA_22 PF13401.6 KFP02127.1 - 0.073 13.3 5.9 1.9 8.8 0.0 3.1 2 1 0 2 2 2 0 AAA domain DUF1492 PF07374.11 KFP02127.1 - 1.8 8.8 8.1 1.8 8.8 0.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1492) Phage_GPO PF05929.11 KFP02127.1 - 2 8.0 14.6 4.2 6.9 14.6 1.6 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase AAA_23 PF13476.6 KFP02128.1 - 8.3e-33 114.6 3.3 8.3e-33 114.6 3.3 10.1 2 1 5 7 7 3 1 AAA domain AAA_15 PF13175.6 KFP02128.1 - 2.9e-12 47.0 19.3 8.5e-10 38.9 0.8 5.4 1 1 2 4 4 2 2 AAA ATPase domain Rad50_zn_hook PF04423.14 KFP02128.1 - 2.4e-11 43.3 0.1 2.4e-11 43.3 0.1 6.0 4 0 0 4 4 4 1 Rad50 zinc hook motif AAA_21 PF13304.6 KFP02128.1 - 4.4e-11 43.2 8.0 1e-05 25.5 0.0 3.9 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KFP02128.1 - 4.9e-07 29.9 0.0 2.9e-06 27.4 0.0 2.4 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 KFP02128.1 - 1e-05 25.1 38.7 2.7e-05 23.7 0.1 3.2 3 2 0 3 3 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFP02128.1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2703 PF10865.8 KFP02128.1 - 0.019 15.1 0.2 0.019 15.1 0.2 5.5 5 2 1 6 6 6 0 Domain of unknown function (DUF2703) AAA_16 PF13191.6 KFP02128.1 - 0.36 11.2 0.0 0.36 11.2 0.0 4.6 5 1 0 5 5 5 0 AAA ATPase domain HCMV_UL139 PF12507.8 KFP02128.1 - 0.38 11.1 0.1 0.38 11.1 0.1 7.3 5 3 2 7 7 6 0 Human Cytomegalovirus UL139 protein AAA_13 PF13166.6 KFP02128.1 - 0.97 8.0 0.0 0.97 8.0 0.0 7.6 3 1 5 8 8 7 0 AAA domain AAA_19 PF13245.6 KFP02128.1 - 4.2 7.7 12.2 15 5.9 0.1 4.4 4 1 0 4 4 4 0 AAA domain IRF PF00605.17 KFP02129.1 - 2.1e-40 137.2 0.6 3.4e-40 136.6 0.6 1.3 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor Sugar_tr PF00083.24 KFP02130.1 - 2.3e-24 86.1 22.8 3.5e-24 85.5 22.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP02130.1 - 3.6e-21 75.5 56.2 3.2e-19 69.1 34.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFP02130.1 - 0.00073 18.2 4.0 0.00073 18.2 4.0 4.5 2 2 1 4 4 4 2 MFS/sugar transport protein DUF4749 PF15936.5 KFP02131.1 - 4.3e-17 63.0 0.0 7.4e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4749) LIM PF00412.22 KFP02131.1 - 3.8e-15 55.8 3.5 6.8e-15 55.0 3.5 1.3 1 0 0 1 1 1 1 LIM domain PDZ PF00595.24 KFP02131.1 - 8.1e-12 45.3 0.1 1.8e-11 44.2 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP02131.1 - 2.9e-08 33.4 0.0 6e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP02131.1 - 0.0014 18.9 0.0 0.0024 18.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain P4Ha_N PF08336.11 KFP02132.1 - 1.1e-39 135.5 0.4 1.1e-39 135.5 0.4 2.0 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 KFP02132.1 - 6.9e-16 58.9 0.0 1.9e-15 57.5 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KFP02132.1 - 6.4e-06 26.6 0.0 1.6e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.28 KFP02133.1 - 1.1e-109 366.9 0.0 1.5e-109 366.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFP02133.1 - 4.9e-05 24.2 0.0 0.00016 22.6 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FNIP_M PF14637.6 KFP02135.1 - 6.4e-89 297.8 0.0 1.2e-88 296.9 0.0 1.5 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain FNIP_C PF14638.6 KFP02135.1 - 5.7e-73 244.6 0.1 1.5e-72 243.3 0.1 1.7 1 0 0 1 1 1 1 Folliculin-interacting protein C-terminus FNIP_N PF14636.6 KFP02135.1 - 5.6e-27 95.6 5.8 3.7e-25 89.7 2.3 3.3 2 1 0 2 2 2 1 Folliculin-interacting protein N-terminus RasGEF_N PF00618.20 KFP02136.1 - 3.8e-14 52.8 0.8 1.3e-12 47.8 0.8 2.5 1 1 0 1 1 1 1 RasGEF N-terminal motif RA PF00788.23 KFP02136.1 - 2.7e-12 47.1 0.0 8.7e-12 45.5 0.0 2.0 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PDZ PF00595.24 KFP02136.1 - 3.2e-12 46.6 0.0 6.6e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain cNMP_binding PF00027.29 KFP02136.1 - 8.2e-12 45.0 0.0 8.4e-07 29.0 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PDZ_6 PF17820.1 KFP02136.1 - 1.4e-11 44.0 0.0 2.8e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP02136.1 - 5.5e-05 23.4 0.0 0.00015 22.0 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Ig_3 PF13927.6 KFP02137.1 - 1.6e-27 95.9 0.0 3.3e-17 62.8 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFP02137.1 - 7e-25 86.9 0.0 4.1e-15 55.6 0.0 3.5 4 0 0 4 4 4 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP02137.1 - 5.1e-15 55.6 0.0 8.2e-09 35.7 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP02137.1 - 5.7e-13 48.8 0.0 3.8e-07 30.2 0.0 3.3 3 1 0 3 3 3 2 Immunoglobulin domain EF-hand_1 PF00036.32 KFP02137.1 - 8.6e-09 34.3 0.0 2.7e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 EF hand Kazal_2 PF07648.15 KFP02137.1 - 2.7e-08 33.8 5.5 2.7e-08 33.8 5.5 2.0 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain EF-hand_6 PF13405.6 KFP02137.1 - 2.3e-07 30.2 0.4 0.0031 17.3 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFP02137.1 - 3.2e-07 29.6 0.0 0.015 14.8 0.0 2.6 2 0 0 2 2 2 2 EF hand V-set PF07686.17 KFP02137.1 - 2.4e-06 27.7 1.5 0.38 11.0 0.0 3.8 2 1 1 3 3 3 2 Immunoglobulin V-set domain Kazal_1 PF00050.21 KFP02137.1 - 1.2e-05 25.2 7.5 3.3e-05 23.8 7.5 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.6 KFP02137.1 - 2.4e-05 24.7 2.2 5.4e-05 23.6 2.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair Ig_6 PF18452.1 KFP02137.1 - 3.3e-05 23.4 0.0 0.018 14.6 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin domain SPARC_Ca_bdg PF10591.9 KFP02137.1 - 0.00014 22.2 0.4 0.00028 21.2 0.4 1.5 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region C2-set_2 PF08205.12 KFP02137.1 - 0.0054 16.8 0.0 0.15 12.2 0.0 2.6 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain EF-hand_8 PF13833.6 KFP02137.1 - 0.007 16.2 0.2 0.71 9.8 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair C1-set PF07654.15 KFP02137.1 - 0.016 15.6 0.0 0.32 11.4 0.0 3.2 4 0 0 4 4 4 0 Immunoglobulin C1-set domain EF-hand_4 PF12763.7 KFP02137.1 - 0.14 12.2 0.2 0.33 10.9 0.2 1.6 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 KFP02137.1 - 0.15 12.0 0.2 18 5.2 0.0 2.4 1 1 1 2 2 2 0 Caleosin related protein Izumo-Ig PF16706.5 KFP02137.1 - 0.21 11.7 1.2 6.4 6.9 0.0 3.0 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain KCT2 PF17818.1 KFP02138.1 - 1.6e-84 282.7 0.6 2.5e-84 282.0 0.6 1.3 1 0 0 1 1 1 1 Keratinocyte-associated gene product TMEM40 PF15817.5 KFP02138.1 - 0.039 13.7 0.1 0.088 12.6 0.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 40 family Porin_3 PF01459.22 KFP02139.1 - 5.6e-82 275.2 3.3 6.3e-82 275.1 3.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin SusE PF14292.6 KFP02139.1 - 0.056 13.7 1.7 0.072 13.3 0.3 1.9 2 0 0 2 2 2 0 SusE outer membrane protein CTNNB1_binding PF08347.11 KFP02140.1 - 2.6e-49 168.2 6.8 2.6e-49 168.2 6.8 1.8 3 0 0 3 3 3 1 N-terminal CTNNB1 binding HMG_box PF00505.19 KFP02140.1 - 1.7e-22 79.6 1.1 3.6e-22 78.6 1.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP02140.1 - 7.5e-09 36.1 1.4 2e-08 34.7 1.4 1.7 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 KFP02140.1 - 0.018 14.4 0.1 0.028 13.8 0.1 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Skp1_POZ PF03931.15 KFP02141.1 - 2.2e-30 104.6 0.7 4.9e-30 103.5 0.2 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 KFP02141.1 - 2.4e-30 104.4 1.6 4.7e-30 103.5 1.6 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Metallophos PF00149.28 KFP02142.1 - 1e-34 120.9 0.5 1.7e-34 120.2 0.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFP02142.1 - 0.016 15.6 0.1 0.034 14.6 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 KFP02142.1 - 0.021 14.5 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF5378 PF17349.2 KFP02142.1 - 0.066 12.5 0.0 0.093 12.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5378) YqzH PF14164.6 KFP02142.1 - 1.7 8.8 3.9 1.5 9.0 1.4 2.1 2 0 0 2 2 2 0 YqzH-like protein UQ_con PF00179.26 KFP02143.1 - 1.9e-51 173.4 0.1 2.1e-51 173.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFP02143.1 - 0.00092 19.5 0.1 0.0013 19.0 0.1 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KFP02143.1 - 0.042 13.7 0.1 0.079 12.8 0.1 1.4 1 1 0 1 1 1 0 UEV domain zf-HC5HC2H_2 PF13832.6 KFP02144.1 - 9.6e-30 103.0 8.0 9.6e-30 103.0 8.0 2.9 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFP02144.1 - 3.7e-23 81.6 8.1 3.7e-23 81.6 8.1 3.7 4 0 0 4 4 4 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KFP02144.1 - 2.6e-12 46.1 7.0 2.6e-12 46.1 7.0 4.0 5 0 0 5 5 5 1 PHD-finger PHD PF00628.29 KFP02144.1 - 2.7e-10 40.0 7.8 2.7e-10 40.0 7.8 3.3 3 0 0 3 3 3 2 PHD-finger EPL1 PF10513.9 KFP02144.1 - 1.3e-06 28.9 1.2 1.3e-06 28.9 1.2 3.2 4 1 0 4 4 4 1 Enhancer of polycomb-like C1_1 PF00130.22 KFP02144.1 - 0.0051 16.7 4.1 0.0051 16.7 4.1 3.3 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FerA PF08165.11 KFP02144.1 - 0.085 12.8 1.3 0.29 11.1 0.2 2.3 2 0 0 2 2 2 0 FerA (NUC095) domain C1_2 PF03107.16 KFP02144.1 - 0.86 10.0 25.0 0.084 13.2 5.0 3.4 3 0 0 3 3 3 0 C1 domain Arf PF00025.21 KFP02145.1 - 8.6e-62 207.7 0.0 9.8e-62 207.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KFP02145.1 - 3.8e-10 39.5 0.0 7.3e-08 32.0 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KFP02145.1 - 9.5e-09 34.9 0.0 1.2e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KFP02145.1 - 2.1e-07 31.2 0.0 4.5e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP02145.1 - 1.3e-06 28.2 0.0 1.3e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KFP02145.1 - 3.2e-06 27.2 0.0 4.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP02145.1 - 0.00054 19.6 0.0 0.006 16.1 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Metalloenzyme PF01676.18 KFP02145.1 - 0.002 17.5 0.0 0.029 13.7 0.0 1.9 1 1 1 2 2 2 1 Metalloenzyme superfamily Gtr1_RagA PF04670.12 KFP02145.1 - 0.0081 15.5 0.0 0.0094 15.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region CAML PF14963.6 KFP02146.1 - 4.3e-115 384.5 0.0 4.8e-115 384.3 0.0 1.0 1 0 0 1 1 1 1 Calcium signal-modulating cyclophilin ligand DUF5568 PF17724.1 KFP02147.1 - 8.5e-97 322.4 10.4 9.4e-97 322.2 10.4 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5568) Thioredoxin PF00085.20 KFP02148.1 - 7.3e-10 38.8 0.0 1.3e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Pterin_4a PF01329.19 KFP02149.1 - 7.5e-32 109.4 0.1 8.4e-32 109.2 0.1 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase IF-2 PF11987.8 KFP02149.1 - 0.039 14.1 0.0 0.12 12.5 0.0 1.7 1 1 1 2 2 2 0 Translation-initiation factor 2 OAR PF03826.17 KFP02150.1 - 1.8e-07 30.8 1.3 4e-07 29.6 1.3 1.7 1 0 0 1 1 1 1 OAR domain Homeodomain PF00046.29 KFP02150.1 - 0.09 12.6 2.2 0.19 11.6 2.2 1.5 1 0 0 1 1 1 0 Homeodomain Macro PF01661.21 KFP02151.1 - 2.4e-28 98.6 0.0 4.3e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 Macro domain Histone_H2A_C PF16211.5 KFP02151.1 - 6.8e-18 64.1 1.5 6.8e-18 64.1 1.5 2.6 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.24 KFP02151.1 - 1.4e-15 57.8 1.9 3e-14 53.5 0.0 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFP02151.1 - 0.0048 17.2 0.0 0.017 15.4 0.0 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1764 PF08576.10 KFP02151.1 - 0.014 16.3 1.7 0.033 15.1 1.7 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Clp_N PF02861.20 KFP02151.1 - 0.093 12.9 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Clp amino terminal domain, pathogenicity island component YihI PF04220.12 KFP02151.1 - 0.12 12.1 5.5 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Der GTPase activator (YihI) HLH PF00010.26 KFP02152.1 - 1.5e-16 60.1 0.1 1.5e-16 60.1 0.1 2.3 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain IL8 PF00048.20 KFP02153.1 - 0.0017 18.5 2.1 0.0023 18.0 2.1 1.2 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like HCO3_cotransp PF00955.21 KFP02154.1 - 6.3e-73 246.3 2.8 8.4e-73 245.9 2.8 1.2 1 0 0 1 1 1 1 HCO3- transporter family Xan_ur_permease PF00860.20 KFP02154.1 - 0.003 16.3 0.9 0.003 16.3 0.9 2.0 2 0 0 2 2 2 1 Permease family ARID PF01388.21 KFP02155.1 - 1e-09 38.9 0.0 1e-09 38.9 0.0 1.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain BSP_II PF05432.11 KFP02156.1 - 0.0036 17.1 5.3 0.0055 16.4 5.3 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Radial_spoke PF04712.12 KFP02156.1 - 0.07 12.1 4.9 0.098 11.6 4.9 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein CENP-B_dimeris PF09026.10 KFP02156.1 - 0.24 11.8 4.3 0.42 11.0 4.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain C2 PF00168.30 KFP02159.1 - 2.2e-22 79.3 0.0 4.9e-13 49.3 0.0 3.4 2 1 0 2 2 2 2 C2 domain Ferlin_C PF16165.5 KFP02159.1 - 4.7e-17 62.4 0.1 7.7e-13 48.7 0.0 2.2 1 1 1 2 2 2 2 Ferlin C-terminus B9-C2 PF07162.11 KFP02159.1 - 0.067 13.4 0.1 0.16 12.2 0.1 1.6 1 1 0 1 1 1 0 Ciliary basal body-associated, B9 protein Lectin_leg-like PF03388.13 KFP02160.1 - 2.4e-80 269.2 0.0 2.9e-80 268.9 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 KFP02160.1 - 6.1e-08 32.9 0.0 8e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial lectin PMP1_2 PF08114.11 KFP02160.1 - 0.0021 17.7 0.2 0.0043 16.8 0.2 1.5 1 0 0 1 1 1 1 ATPase proteolipid family DUF4134 PF13572.6 KFP02160.1 - 0.052 13.8 0.1 0.1 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) Col_cuticle_N PF01484.17 KFP02160.1 - 0.11 12.6 0.8 0.22 11.6 0.8 1.5 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain DUF21 PF01595.20 KFP02161.1 - 3.4e-29 101.8 0.0 5.5e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KFP02161.1 - 2.2e-07 31.2 0.2 0.00062 20.2 0.0 2.7 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.29 KFP02161.1 - 0.016 15.3 0.1 0.31 11.1 0.0 2.4 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain Sema PF01403.19 KFP02162.1 - 2.5e-89 300.0 0.2 2.8e-89 299.9 0.2 1.0 1 0 0 1 1 1 1 Sema domain Sec63 PF02889.16 KFP02163.1 - 2.5e-20 72.8 0.1 3.4e-20 72.3 0.1 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DUF603 PF04645.12 KFP02163.1 - 0.0006 19.6 0.3 0.001 18.8 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function, DUF603 WD40 PF00400.32 KFP02164.1 - 4.1e-25 87.5 13.6 1.8e-08 34.9 0.6 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP02164.1 - 5e-10 39.6 0.3 0.00016 21.9 0.2 3.9 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KFP02164.1 - 0.18 10.8 0.1 0.76 8.8 0.2 1.7 1 1 1 2 2 2 0 Coatomer WD associated region DUF2387 PF09526.10 KFP02164.1 - 5.2 7.3 6.6 21 5.4 0.1 3.7 4 0 0 4 4 4 0 Probable metal-binding protein (DUF2387) EMP24_GP25L PF01105.24 KFP02165.1 - 1e-42 146.2 0.0 1.2e-42 145.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 KFP02165.1 - 0.047 13.9 0.0 0.068 13.4 0.0 1.3 1 0 0 1 1 1 0 SdrD B-like domain CarboxypepD_reg PF13620.6 KFP02165.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain MRP-S24 PF14955.6 KFP02166.1 - 5.4e-48 162.4 0.0 5.9e-48 162.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S24 zf-tcix PF14952.6 KFP02167.1 - 1.8e-20 72.2 6.8 1.8e-20 72.2 6.8 1.9 2 0 0 2 2 2 1 Putative treble-clef, zinc-finger, Zn-binding Mu-like_Com PF10122.9 KFP02167.1 - 0.003 17.0 1.8 0.013 14.9 1.8 2.1 1 0 0 1 1 1 1 Mu-like prophage protein Com Dynein_C PF18199.1 KFP02167.1 - 0.093 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Dynein heavy chain C-terminal domain Histone PF00125.24 KFP02168.1 - 5.6e-19 68.8 0.0 6.3e-19 68.6 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KFP02168.1 - 3.9e-12 45.7 0.2 7.3e-12 44.8 0.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KFP02168.1 - 0.0091 16.3 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone S-AdoMet_synt_C PF02773.16 KFP02169.1 - 6.2e-68 227.1 0.0 1.1e-67 226.2 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.20 KFP02169.1 - 6.2e-35 119.8 0.4 1e-34 119.1 0.4 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 KFP02169.1 - 1.8e-15 57.2 0.3 5.1e-15 55.8 0.1 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain Synaptobrevin PF00957.21 KFP02170.1 - 2.3e-25 88.2 0.1 2.5e-25 88.1 0.1 1.0 1 0 0 1 1 1 1 Synaptobrevin MCU PF04678.13 KFP02170.1 - 0.0074 16.4 0.1 0.0081 16.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial calcium uniporter DUF2721 PF11026.8 KFP02170.1 - 0.024 14.5 0.4 0.029 14.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Sec20 PF03908.13 KFP02170.1 - 0.048 13.6 0.2 0.074 13.0 0.2 1.4 1 0 0 1 1 1 0 Sec20 Integrase_H2C2 PF17921.1 KFP02170.1 - 0.098 12.8 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Integrase zinc binding domain OppC_N PF12911.7 KFP02170.1 - 0.21 11.6 1.4 0.31 11.0 1.4 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C UCH PF00443.29 KFP02171.1 - 1.3e-40 139.5 0.4 1.6e-40 139.2 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP02171.1 - 2.4e-05 24.1 1.0 0.00025 20.7 1.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFP02171.1 - 4.7e-05 23.6 0.2 0.00011 22.4 0.2 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Hexokinase_2 PF03727.16 KFP02172.1 - 2.8e-176 583.5 0.6 2.3e-88 295.7 0.1 2.3 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.21 KFP02172.1 - 4.1e-146 483.8 0.3 1.2e-72 244.0 0.1 2.3 2 0 0 2 2 2 2 Hexokinase CSD PF00313.22 KFP02172.1 - 0.096 12.6 0.0 0.65 9.9 0.0 2.2 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain FGGY_N PF00370.21 KFP02172.1 - 0.12 11.9 0.0 3.8 7.0 0.0 2.2 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain BTB PF00651.31 KFP02173.1 - 5.8e-15 55.5 0.0 4e-14 52.8 0.0 2.3 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFP02173.1 - 1e-06 28.7 1.0 3.1e-06 27.2 0.2 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch Annexin PF00191.20 KFP02174.1 - 5.2e-36 122.5 0.4 5.8e-26 90.4 0.1 2.0 2 0 0 2 2 2 2 Annexin Pkinase PF00069.25 KFP02175.1 - 3.4e-42 144.6 0.0 3.4e-42 144.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP02175.1 - 6.4e-25 87.9 0.0 6.4e-25 87.9 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP02175.1 - 2e-07 30.6 0.0 2e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFP02175.1 - 0.02 13.7 0.0 0.02 13.7 0.0 2.6 2 1 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 KFP02175.1 - 0.028 13.4 0.0 0.028 13.4 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 KFP02175.1 - 0.081 12.8 0.3 0.081 12.8 0.3 3.1 2 2 1 3 3 3 0 Phosphotransferase enzyme family BMP2K_C PF15282.6 KFP02176.1 - 0.007 16.3 0.1 0.0079 16.1 0.1 1.1 1 0 0 1 1 1 1 BMP-2-inducible protein kinase C-terminus BMP2K_C PF15282.6 KFP02177.1 - 3e-32 112.5 18.5 2.5e-26 93.1 6.1 3.2 2 2 1 3 3 3 2 BMP-2-inducible protein kinase C-terminus Nfu_N PF08712.11 KFP02178.1 - 1.2e-34 118.2 0.0 2e-34 117.5 0.0 1.4 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KFP02178.1 - 8.7e-26 89.9 0.1 1.2e-25 89.4 0.1 1.2 1 0 0 1 1 1 1 NifU-like domain SIS PF01380.22 KFP02179.1 - 4e-69 230.5 0.1 2e-36 124.8 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KFP02179.1 - 4.3e-16 59.3 0.0 1.6e-15 57.5 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KFP02179.1 - 8e-12 45.1 0.0 1.9e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KFP02179.1 - 8.1e-05 21.7 0.0 0.00014 20.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 KFP02179.1 - 0.00052 18.8 0.0 0.00094 18.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 KFP02179.1 - 0.021 14.9 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 SIS domain Ant_C PF05586.11 KFP02180.1 - 5.7e-44 148.6 0.5 7e-44 148.3 0.5 1.1 1 0 0 1 1 1 1 Anthrax receptor C-terminus region Sulfotransfer_1 PF00685.27 KFP02181.1 - 4.3e-35 121.5 0.3 5.4e-35 121.2 0.3 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP02181.1 - 1.4e-10 42.0 0.0 8.6e-06 26.3 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFP02181.1 - 0.0029 17.5 0.2 0.0045 16.9 0.2 1.3 1 0 0 1 1 1 1 Sulfotransferase family Hist_deacetyl PF00850.19 KFP02182.1 - 8.1e-86 288.3 0.1 1.1e-85 287.8 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Laminin_G_2 PF02210.24 KFP02184.1 - 2.3e-93 309.4 0.1 9.9e-23 81.1 0.1 5.8 5 1 0 5 5 5 5 Laminin G domain Laminin_G_1 PF00054.23 KFP02184.1 - 2.3e-75 251.1 0.0 1.1e-20 74.2 0.0 5.5 5 0 0 5 5 5 5 Laminin G domain Laminin_II PF06009.12 KFP02184.1 - 1.5e-32 112.5 2.2 1.5e-32 112.5 2.2 3.8 3 1 1 4 4 4 2 Laminin Domain II Laminin_EGF PF00053.24 KFP02184.1 - 6.6e-23 80.6 65.9 7.2e-11 42.1 10.3 5.6 4 1 1 5 5 5 3 Laminin EGF domain Laminin_G_3 PF13385.6 KFP02184.1 - 2.2e-17 63.6 0.0 2.1e-07 31.2 0.0 5.1 5 0 0 5 5 5 2 Concanavalin A-like lectin/glucanases superfamily Laminin_I PF06008.14 KFP02184.1 - 0.056 13.1 18.7 0.065 12.9 0.1 4.0 3 1 1 4 4 4 0 Laminin Domain I Tubulin PF00091.25 KFP02185.1 - 6e-65 219.1 0.0 8.6e-65 218.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFP02185.1 - 1.8e-30 105.7 0.0 3e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 KFP02185.1 - 0.00051 19.3 0.0 0.00079 18.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin like Tubulin_3 PF14881.6 KFP02185.1 - 0.015 15.0 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain XTBD PF11952.8 KFP02185.1 - 0.058 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 XRN-Two Binding Domain, XTBD IGFBP PF00219.18 KFP02186.1 - 9e-11 42.3 21.1 9e-11 42.3 21.1 4.1 3 2 1 4 4 4 1 Insulin-like growth factor binding protein Cys_knot PF00007.22 KFP02186.1 - 2.2e-05 24.7 12.6 2.2e-05 24.7 12.6 3.5 2 1 1 3 3 3 1 Cystine-knot domain VWC PF00093.18 KFP02186.1 - 0.00066 19.9 0.2 0.00066 19.9 0.2 5.0 4 2 0 4 4 4 1 von Willebrand factor type C domain Pkinase_Tyr PF07714.17 KFP02188.1 - 1.8e-92 309.3 0.0 2.4e-92 308.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP02188.1 - 2.3e-46 158.3 0.0 3.5e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFP02188.1 - 5.8e-29 100.0 0.3 1.3e-28 98.9 0.3 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFP02188.1 - 1.1e-20 72.9 0.3 6.2e-20 70.6 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFP02188.1 - 2.2e-13 49.8 0.4 5.7e-13 48.5 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KFP02188.1 - 7.8e-12 44.7 0.0 3e-11 42.8 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain Haspin_kinase PF12330.8 KFP02188.1 - 0.0067 15.4 0.0 0.03 13.3 0.0 1.8 1 1 0 1 1 1 1 Haspin like kinase domain SH3_10 PF17902.1 KFP02188.1 - 0.015 15.4 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 SH3 domain SH3_3 PF08239.11 KFP02188.1 - 0.046 14.0 0.1 0.099 12.9 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain zf-RING_14 PF17978.1 KFP02188.1 - 0.083 13.3 0.1 0.41 11.1 0.0 2.1 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain SEFIR PF08357.11 KFP02189.1 - 9.9e-33 113.5 0.1 1.4e-32 113.1 0.1 1.2 1 0 0 1 1 1 1 SEFIR domain TIR_2 PF13676.6 KFP02189.1 - 4.3e-05 24.1 0.0 6.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 TIR domain DUF4683 PF15735.5 KFP02190.1 - 5.4e-172 572.9 14.0 5.4e-172 572.9 14.0 5.7 7 1 0 7 7 7 1 Domain of unknown function (DUF4683) DNA_pol_B PF00136.21 KFP02190.1 - 2.1e-98 330.0 0.1 3.5e-98 329.3 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KFP02190.1 - 3.8e-26 92.0 0.1 1e-14 54.5 0.1 3.0 3 1 0 3 3 3 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KFP02190.1 - 2.8e-13 50.1 11.6 2e-12 47.4 11.6 2.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta MFS_1 PF07690.16 KFP02191.1 - 3.3e-18 65.8 42.5 6.6e-10 38.4 24.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KFP02192.1 - 1.9e-28 99.4 45.2 1.5e-15 57.0 26.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ras PF00071.22 KFP02193.1 - 8.4e-05 22.2 0.0 9.1e-05 22.1 0.0 1.0 1 0 0 1 1 1 1 Ras family ATP_bind_1 PF03029.17 KFP02193.1 - 0.13 12.0 0.0 0.15 11.8 0.0 1.0 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein rve PF00665.26 KFP02194.1 - 3.5e-16 59.5 0.0 6.1e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_Zn PF02022.19 KFP02194.1 - 1.7e-06 27.9 2.0 4.4e-06 26.5 2.0 1.7 1 0 0 1 1 1 1 Integrase Zinc binding domain B12-binding_2 PF02607.17 KFP02194.1 - 0.16 12.4 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain FH2 PF02181.23 KFP02195.1 - 2.4e-97 326.4 13.7 1.2e-96 324.1 13.7 2.1 1 1 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 KFP02195.1 - 1.7e-61 207.3 3.6 1.7e-61 207.3 3.6 2.5 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 KFP02195.1 - 3.3e-49 167.0 0.6 1.3e-48 165.1 0.5 2.1 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain FlaC_arch PF05377.11 KFP02195.1 - 0.099 13.1 2.0 1.6 9.2 0.1 3.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Ion_trans_2 PF07885.16 KFP02196.1 - 1.8e-33 114.3 16.0 1.2e-18 66.8 0.3 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 KFP02196.1 - 1.1e-05 24.8 8.5 0.00058 19.2 1.0 2.3 1 1 1 2 2 2 2 Ion transport protein Ion_trans_2 PF07885.16 KFP02197.1 - 3.5e-31 107.0 10.6 1.4e-17 63.4 1.7 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 KFP02197.1 - 0.00046 19.5 3.7 0.0011 18.3 0.2 2.1 2 0 0 2 2 2 1 Ion transport protein IRK PF01007.20 KFP02197.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.6 3 0 0 3 3 3 0 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 KFP02198.1 - 2.6e-30 104.2 19.6 8.5e-18 64.1 2.0 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 KFP02198.1 - 0.0051 16.1 9.9 0.018 14.3 0.4 2.3 2 1 0 2 2 2 2 Ion transport protein DUF4312 PF14189.6 KFP02198.1 - 0.093 12.7 0.4 0.2 11.7 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4312) 7tm_2 PF00002.24 KFP02199.1 - 5.8e-81 271.4 24.8 8.3e-81 270.9 24.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFP02199.1 - 3.6e-16 59.2 3.4 9.4e-16 57.9 3.4 1.8 1 0 0 1 1 1 1 Hormone receptor domain Dicty_CAR PF05462.11 KFP02199.1 - 2e-05 23.9 17.4 2e-05 23.9 17.4 1.6 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor Glyoxalase PF00903.25 KFP02200.1 - 1.2e-25 90.1 0.0 1.5e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KFP02200.1 - 4.1e-09 36.7 0.0 1.5e-08 34.9 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KFP02200.1 - 6.7e-06 26.9 0.0 1.2e-05 26.1 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KFP02200.1 - 0.022 14.7 0.0 2 8.4 0.0 2.2 1 1 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KFP02200.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.8 3 0 0 3 3 3 0 Glyoxalase-like domain PIG-X PF08320.12 KFP02200.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 PIG-X / PBN1 BTB PF00651.31 KFP02201.1 - 6.8e-28 97.1 0.2 2.9e-26 91.9 0.0 2.5 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFP02201.1 - 6.8e-24 83.9 0.4 1.6e-22 79.5 0.4 2.4 1 1 1 2 2 2 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 KFP02201.1 - 1.6e-22 80.0 0.1 1.1e-10 41.7 0.1 2.2 2 0 0 2 2 2 2 F5/8 type C domain DUF3342 PF11822.8 KFP02201.1 - 0.076 13.2 0.0 1.7 8.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) zf-AN1 PF01428.16 KFP02202.1 - 1.2e-08 34.9 8.0 2.8e-08 33.8 8.0 1.6 1 0 0 1 1 1 1 AN1-like Zinc finger Yae1_N PF09811.9 KFP02203.1 - 4.8e-09 35.8 29.6 0.016 14.9 18.7 3.3 2 1 0 2 2 2 2 Essential protein Yae1, N terminal Ig_3 PF13927.6 KFP02204.1 - 3.6e-70 232.6 13.5 4.7e-13 49.5 0.3 6.7 7 0 0 7 7 6 6 Immunoglobulin domain I-set PF07679.16 KFP02204.1 - 2.2e-60 200.7 0.0 1.7e-11 44.0 0.0 6.4 6 0 0 6 6 6 6 Immunoglobulin I-set domain MAM PF00629.23 KFP02204.1 - 2.3e-50 170.7 0.0 5.3e-50 169.5 0.0 1.7 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Ig_2 PF13895.6 KFP02204.1 - 1e-47 160.3 4.7 3.8e-07 30.3 0.2 6.6 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.25 KFP02204.1 - 2.7e-47 158.8 2.1 8.1e-09 35.5 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin domain V-set PF07686.17 KFP02204.1 - 1.5e-25 89.5 13.6 0.0016 18.6 0.1 10.7 6 5 2 8 8 8 4 Immunoglobulin V-set domain Ig_5 PF16681.5 KFP02204.1 - 9.1e-10 38.8 0.0 3.2 8.2 0.0 6.0 5 0 0 5 5 5 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KFP02204.1 - 4.1e-09 36.4 2.3 0.79 9.8 0.0 5.4 5 0 0 5 5 5 3 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFP02204.1 - 6.5e-09 35.9 0.1 0.43 10.9 0.0 6.0 5 1 0 5 5 5 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFP02204.1 - 1e-08 34.6 1.3 0.15 11.6 0.0 6.0 6 0 0 6 6 6 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFP02204.1 - 1.2e-05 25.3 1.7 9.1 6.4 0.0 5.7 6 0 0 6 6 6 1 Izumo-like Immunoglobulin domain C1-set PF07654.15 KFP02204.1 - 0.00031 21.1 0.5 0.8 10.1 0.0 4.7 4 0 0 4 4 4 1 Immunoglobulin C1-set domain CCDC-167 PF15188.6 KFP02205.1 - 1.1e-27 96.2 2.6 1.2e-27 96.1 2.6 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 FtsJ PF01728.19 KFP02206.1 - 4.6e-38 131.1 0.0 8.5e-38 130.2 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase G-patch PF01585.23 KFP02206.1 - 8.7e-13 47.9 2.3 2.5e-12 46.5 2.3 1.9 1 0 0 1 1 1 1 G-patch domain WW PF00397.26 KFP02206.1 - 9.9e-05 22.3 2.0 0.00023 21.2 0.0 2.3 2 0 0 2 2 2 1 WW domain mRNA_cap_enzyme PF01331.19 KFP02206.1 - 0.0026 17.6 0.1 0.0064 16.3 0.1 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.21 KFP02206.1 - 0.018 14.7 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 ATP dependent DNA ligase domain G-patch_2 PF12656.7 KFP02206.1 - 0.033 14.3 2.9 0.051 13.7 1.3 2.1 2 0 0 2 2 2 0 G-patch domain zf-C3HC4_3 PF13920.6 KFP02207.1 - 1.6e-10 40.7 9.4 1.6e-10 40.7 9.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP02207.1 - 9.2e-10 38.2 15.0 1.3e-09 37.7 12.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP02207.1 - 3.8e-09 36.2 11.6 6.3e-09 35.5 10.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFP02207.1 - 3.7e-08 33.4 7.7 3.7e-08 33.4 7.7 2.4 3 1 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFP02207.1 - 4.6e-08 33.3 11.6 4.6e-08 33.3 11.6 2.2 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 KFP02207.1 - 5.5e-08 32.7 7.2 1.5e-07 31.3 3.5 2.4 1 1 1 2 2 2 2 RING-type zinc-finger zf-RING_5 PF14634.6 KFP02207.1 - 4.8e-07 29.6 11.4 4.8e-07 29.6 11.4 1.9 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP02207.1 - 1.7e-06 27.8 9.0 1.7e-06 27.8 9.0 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFP02207.1 - 4.4e-06 26.9 12.3 3.3e-05 24.1 11.2 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFP02207.1 - 0.00046 20.2 4.0 0.0012 18.9 4.0 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 KFP02207.1 - 0.0011 18.8 4.8 0.0011 18.8 4.8 2.2 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KFP02207.1 - 0.018 15.2 7.2 0.018 15.2 7.2 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 KFP02207.1 - 2.7 7.8 18.3 3.7 7.4 1.0 3.0 2 1 0 2 2 2 0 RING-like zinc finger FHA PF00498.26 KFP02208.1 - 2.2e-16 59.9 0.0 3.5e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFP02208.1 - 1.4e-05 25.3 0.0 2.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain tRNA-synt_2c PF01411.19 KFP02209.1 - 4.8e-189 629.4 0.0 6.3e-189 629.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KFP02209.1 - 1.2e-07 31.7 1.2 2e-07 31.0 0.2 2.0 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KFP02209.1 - 2.2e-05 24.9 0.0 5.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 DHHA1 domain LRR_6 PF13516.6 KFP02210.1 - 1.1e-20 71.8 28.2 3.1e-06 26.8 0.4 8.0 8 0 0 8 8 8 6 Leucine Rich repeat LRR_4 PF12799.7 KFP02210.1 - 4.5e-05 23.7 17.0 0.0022 18.3 0.3 4.9 5 1 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP02210.1 - 0.00015 21.8 12.0 1.5 9.7 0.0 6.2 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_8 PF13855.6 KFP02210.1 - 0.001 18.8 19.9 0.0085 15.8 1.0 5.4 2 1 4 6 6 6 4 Leucine rich repeat GnHR_trans PF12369.8 KFP02210.1 - 0.51 11.2 1.9 5 8.0 0.0 2.9 3 0 0 3 3 3 0 Gonadotropin hormone receptor transmembrane region TMEM151 PF14857.6 KFP02211.1 - 6.2e-216 717.3 19.1 8.3e-216 716.9 19.1 1.1 1 0 0 1 1 1 1 TMEM151 family UAA PF08449.11 KFP02212.1 - 1.8e-78 263.8 19.9 2.2e-78 263.5 19.9 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KFP02212.1 - 7.8e-08 32.6 22.9 0.00025 21.2 15.4 2.6 2 1 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 KFP02212.1 - 0.004 16.1 15.0 0.03 13.3 4.2 2.1 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 KFP02212.1 - 0.069 12.5 11.9 0.085 12.2 5.9 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family MNHE PF01899.16 KFP02212.1 - 0.43 10.3 4.4 0.86 9.3 0.5 2.5 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit DUF983 PF06170.12 KFP02212.1 - 6.3 7.3 8.2 0.77 10.2 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF983) HSP90 PF00183.18 KFP02213.1 - 1.8e-235 782.8 28.2 2.3e-235 782.4 28.2 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KFP02213.1 - 3e-13 50.2 0.0 6.8e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFP02213.1 - 5.4e-10 39.2 0.1 1.6e-09 37.7 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 KFP02213.1 - 0.11 12.6 0.3 0.38 10.8 0.1 2.1 2 0 0 2 2 2 0 Tumour suppressor protein Med26 PF08711.11 KFP02213.1 - 4.8 7.3 7.9 1.9 8.6 0.0 3.5 4 0 0 4 4 4 0 TFIIS helical bundle-like domain CDC45 PF02724.14 KFP02213.1 - 9.8 4.3 14.6 19 3.4 14.6 1.4 1 0 0 1 1 1 0 CDC45-like protein Nucleoside_tran PF01733.18 KFP02214.1 - 9.6e-107 356.9 10.8 1.5e-106 356.3 10.8 1.3 1 0 0 1 1 1 1 Nucleoside transporter Spectrin PF00435.21 KFP02216.1 - 0.0081 16.6 1.8 4.7 7.8 1.2 2.5 2 1 0 2 2 2 2 Spectrin repeat DUF3037 PF11236.8 KFP02216.1 - 0.12 12.8 0.1 0.18 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) Peptidase_C2 PF00648.21 KFP02217.1 - 8.6e-127 422.2 0.0 1.2e-126 421.8 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KFP02217.1 - 2.2e-53 180.3 0.0 3.7e-53 179.6 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_6 PF13405.6 KFP02217.1 - 2e-07 30.4 1.0 0.0031 17.3 0.0 4.8 4 0 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.6 KFP02217.1 - 2.1e-07 30.6 0.4 4.1e-05 23.3 0.2 3.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP02217.1 - 1.1e-06 27.8 2.3 0.043 13.4 0.0 4.6 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.6 KFP02217.1 - 0.00022 21.6 2.7 2.1 8.9 0.1 4.3 3 2 0 3 3 3 2 EF-hand domain pair RSN1_7TM PF02714.15 KFP02218.1 - 5.1e-62 209.7 23.1 1.3e-61 208.4 23.1 1.7 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KFP02218.1 - 4.3e-39 134.6 0.2 6.4e-39 134.0 0.2 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KFP02218.1 - 2.7e-19 69.5 0.0 2.7e-19 69.5 0.0 5.6 6 1 1 7 7 7 1 Late exocytosis, associated with Golgi transport RRM_1 PF00076.22 KFP02218.1 - 0.086 12.7 0.1 3.9 7.4 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4006 PF13179.6 KFP02218.1 - 5.8 6.9 7.0 29 4.7 0.5 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF4006) Ribosomal_L14 PF00238.19 KFP02219.1 - 1.8e-16 60.3 0.0 1.4e-15 57.5 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein L14p/L23e PDGF PF00341.17 KFP02220.1 - 5e-26 90.8 5.6 5e-26 90.8 5.6 2.2 2 1 0 2 2 2 1 PDGF/VEGF domain VEGF_C PF14554.6 KFP02220.1 - 2.1e-25 88.6 14.6 2.1e-25 88.6 14.6 2.6 3 0 0 3 3 3 1 VEGF heparin-binding domain DUF3408 PF11888.8 KFP02220.1 - 0.034 14.3 1.3 0.034 14.3 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Yae1_N PF09811.9 KFP02221.1 - 7.5e-18 64.0 63.3 1.8e+04 -28.1 63.3 6.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Radial_spoke PF04712.12 KFP02222.1 - 3.9e-05 22.8 0.3 7.4e-05 21.9 0.2 1.9 1 1 0 1 1 1 1 Radial spokehead-like protein EHN PF06441.12 KFP02223.1 - 2.7e-34 117.8 0.1 5.4e-34 116.8 0.1 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KFP02223.1 - 2.6e-25 89.5 0.0 8.5e-25 87.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFP02223.1 - 3.1e-05 24.7 0.0 7.9e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family p31comet PF06581.12 KFP02224.1 - 1.3e-70 237.6 0.0 1.8e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Mad1 and Cdc20-bound-Mad2 binding GTP_EFTU PF00009.27 KFP02225.1 - 2e-26 92.7 0.0 3.3e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KFP02225.1 - 3.5e-05 24.1 0.0 0.00018 21.9 0.0 2.3 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFP02225.1 - 0.00096 19.2 0.0 0.0028 17.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP02225.1 - 0.0016 18.3 0.0 0.07 13.0 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 KFP02225.1 - 0.0035 17.1 0.1 20 4.9 0.0 3.4 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 KFP02225.1 - 0.027 14.6 0.1 2.2 8.3 0.2 2.4 1 1 1 2 2 2 0 Dynamin family GTP_EFTU_D3 PF03143.17 KFP02225.1 - 0.047 14.0 0.3 0.11 12.8 0.1 1.8 2 0 0 2 2 2 0 Elongation factor Tu C-terminal domain SRPRB PF09439.10 KFP02225.1 - 0.052 13.0 0.2 6.1 6.2 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KFP02225.1 - 0.078 12.5 0.1 4.4 6.8 0.1 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 KFP02225.1 - 0.14 12.0 0.1 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein zf_UBZ PF18439.1 KFP02226.1 - 1.1e-12 47.3 2.3 3.4e-12 45.7 2.3 1.9 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 KFP02226.1 - 4.3e-11 43.5 0.0 9e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS PF00817.20 KFP02226.1 - 1.9e-08 34.5 0.0 6.4e-07 29.5 0.0 2.5 2 0 0 2 2 2 1 impB/mucB/samB family Xpo1 PF08389.12 KFP02227.1 - 9.7e-36 123.1 2.7 2.4e-35 121.8 1.9 2.2 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 KFP02227.1 - 2.4e-05 24.1 0.0 0.00012 21.9 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain RNA_pol_A_bac PF01000.26 KFP02228.1 - 8e-30 103.5 0.0 1.3e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KFP02228.1 - 3.8e-22 77.5 0.0 4.9e-22 77.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain INCENP_N PF12178.8 KFP02228.1 - 0.11 12.5 0.7 9.9 6.3 0.0 2.6 2 0 0 2 2 2 0 Chromosome passenger complex (CPC) protein INCENP N terminal Yip1 PF04893.17 KFP02229.1 - 1.1e-06 28.5 16.5 1.1e-06 28.5 16.5 1.4 1 1 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 KFP02229.1 - 0.00049 19.7 11.2 0.042 13.4 11.2 2.2 1 1 0 1 1 1 1 YIF1 Romo1 PF10247.9 KFP02229.1 - 0.011 16.1 0.9 0.032 14.6 0.9 1.9 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Yip1 PF04893.17 KFP02230.1 - 1.9e-06 27.7 17.8 1.9e-06 27.7 17.8 1.5 1 1 0 1 1 1 1 Yip1 domain Romo1 PF10247.9 KFP02230.1 - 0.017 15.5 2.5 0.043 14.2 2.2 2.0 1 1 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 YIF1 PF03878.15 KFP02230.1 - 0.46 10.0 10.3 0.64 9.5 10.2 1.3 1 1 0 1 1 1 0 YIF1 LRR_6 PF13516.6 KFP02231.1 - 1.7e-10 40.1 4.5 0.11 12.5 0.2 5.6 6 0 0 6 6 6 4 Leucine Rich repeat LRR_1 PF00560.33 KFP02231.1 - 5.6e-06 26.2 1.2 3.6 8.5 0.0 5.1 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_4 PF12799.7 KFP02231.1 - 0.00017 21.9 3.5 6.9 7.2 1.2 4.2 2 2 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP02231.1 - 0.24 11.2 6.9 11 5.8 0.4 4.1 3 2 0 3 3 3 0 Leucine rich repeat Pilt PF15453.6 KFP02232.1 - 6.2e-145 483.2 27.1 8.1e-116 387.4 17.5 2.6 1 1 1 2 2 2 2 Protein incorporated later into Tight Junctions Spc7 PF08317.11 KFP02232.1 - 0.01 14.8 14.2 0.016 14.1 12.2 2.2 2 1 1 3 3 3 1 Spc7 kinetochore protein HMMR_N PF15905.5 KFP02232.1 - 0.067 12.7 15.4 0.11 12.0 15.4 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Lebercilin PF15619.6 KFP02232.1 - 0.28 10.8 18.0 2 8.1 17.9 2.1 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF641 PF04859.12 KFP02232.1 - 0.59 10.5 7.3 0.18 12.1 2.9 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Fib_alpha PF08702.10 KFP02232.1 - 0.64 10.2 7.0 1.1 9.5 5.9 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 KFP02232.1 - 1.1 8.6 4.5 1.1 8.5 3.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 KFP02232.1 - 1.3 9.4 11.6 0.83 10.0 9.4 1.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 KFP02232.1 - 1.5 8.3 6.3 3 7.3 6.3 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Syntaxin_2 PF14523.6 KFP02232.1 - 1.7 9.1 6.2 0.81 10.1 2.4 2.3 3 0 0 3 3 2 0 Syntaxin-like protein HIP1_clath_bdg PF16515.5 KFP02232.1 - 3.5 8.3 15.5 0.37 11.4 10.2 2.2 2 0 0 2 2 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Syntaxin-6_N PF09177.11 KFP02232.1 - 5 7.7 12.0 0.64 10.6 2.5 3.2 2 1 1 3 3 3 0 Syntaxin 6, N-terminal V_ATPase_I PF01496.19 KFP02232.1 - 5.4 4.8 7.5 6.1 4.6 6.7 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Tropomyosin_1 PF12718.7 KFP02232.1 - 5.7 7.1 20.8 8.8 6.5 10.7 2.3 1 1 1 2 2 2 0 Tropomyosin like DUF4795 PF16043.5 KFP02232.1 - 7.4 6.1 12.6 6.2 6.4 10.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Wtap PF17098.5 KFP02232.1 - 8.4 6.3 13.6 8.7 6.3 10.0 2.6 1 1 1 2 2 2 0 WTAP/Mum2p family ADIP PF11559.8 KFP02232.1 - 8.5 6.4 17.7 38 4.3 6.1 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMPIT PF07851.13 KFP02232.1 - 9 5.4 7.0 2.1 7.5 3.0 1.7 1 1 1 2 2 2 0 TMPIT-like protein EGF PF00008.27 KFP02233.1 - 3.8e-28 97.4 79.1 1.1e-07 32.0 7.3 6.4 6 0 0 6 6 6 5 EGF-like domain hEGF PF12661.7 KFP02233.1 - 4.8e-17 61.9 78.9 2.1e-05 25.0 5.0 7.4 7 0 0 7 7 7 5 Human growth factor-like EGF EGF_2 PF07974.13 KFP02233.1 - 1.2e-07 31.9 103.1 0.021 15.2 10.5 6.3 6 0 0 6 6 6 5 EGF-like domain Laminin_EGF PF00053.24 KFP02233.1 - 0.058 13.6 84.6 0.33 11.1 16.3 6.4 2 2 4 6 6 6 0 Laminin EGF domain EGF_3 PF12947.7 KFP02233.1 - 1.5 9.1 69.9 0.31 11.3 5.1 6.5 2 2 3 5 5 5 0 EGF domain EGF_CA PF07645.15 KFP02233.1 - 2.1 8.6 87.8 0.1 12.8 6.9 6.4 3 1 3 6 6 6 0 Calcium-binding EGF domain zf-C2H2_jaz PF12171.8 KFP02234.1 - 0.00019 21.6 1.9 0.00019 21.6 1.9 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFP02234.1 - 0.014 15.7 2.4 2 8.8 0.3 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFP02234.1 - 8.3 7.0 15.1 0.43 11.0 1.9 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF2465 PF10239.9 KFP02235.1 - 6.1e-131 436.4 0.0 7.9e-131 436.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) RasGEF PF00617.19 KFP02236.1 - 6.4e-46 156.8 0.5 1e-45 156.1 0.5 1.3 1 0 0 1 1 1 1 RasGEF domain C1_1 PF00130.22 KFP02236.1 - 2.3e-13 49.8 9.3 5.5e-13 48.6 9.3 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_1 PF00036.32 KFP02236.1 - 1.2e-09 37.0 5.4 0.00017 20.9 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFP02236.1 - 3e-09 36.1 1.4 0.0002 21.0 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFP02236.1 - 5.6e-09 35.1 0.4 0.0048 16.3 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFP02236.1 - 8.2e-09 35.8 3.8 0.00065 20.1 0.1 3.6 4 0 0 4 4 4 2 EF-hand domain pair RasGEF_N PF00618.20 KFP02236.1 - 6e-07 29.7 0.1 2.6e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif EF-hand_8 PF13833.6 KFP02236.1 - 2.9e-05 23.8 1.2 0.086 12.7 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair EGF_CA PF07645.15 KFP02237.1 - 2.9e-101 331.5 240.6 2.2e-09 37.4 6.1 17.6 17 1 0 17 17 17 15 Calcium-binding EGF domain TB PF00683.17 KFP02237.1 - 6e-52 173.2 68.6 1.1e-16 60.2 9.9 6.4 6 0 0 6 6 6 4 TB domain cEGF PF12662.7 KFP02237.1 - 1.6e-50 168.6 146.3 1.8e-07 31.0 2.6 17.4 16 1 0 16 16 16 12 Complement Clr-like EGF-like EGF PF00008.27 KFP02237.1 - 2.1e-33 114.2 228.0 0.00029 21.1 7.1 18.0 17 0 0 17 17 17 14 EGF-like domain EGF_3 PF12947.7 KFP02237.1 - 6.3e-17 61.5 188.6 0.00041 20.5 6.2 18.3 16 2 1 17 17 17 12 EGF domain hEGF PF12661.7 KFP02237.1 - 6.2e-16 58.4 212.1 0.00014 22.4 1.9 19.4 19 1 0 19 19 19 10 Human growth factor-like EGF FXa_inhibition PF14670.6 KFP02237.1 - 2.3e-08 34.2 246.8 0.00048 20.4 7.4 18.7 16 3 3 19 19 19 10 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 KFP02237.1 - 0.00022 21.5 13.5 0.0014 18.9 3.4 16.1 16 1 0 16 16 16 7 Pvs28 EGF domain EGF_MSP1_1 PF12946.7 KFP02237.1 - 0.00062 19.8 1.8 0.00062 19.8 1.8 18.5 21 0 0 21 21 21 7 MSP1 EGF domain 1 Lipase_GDSL_2 PF13472.6 KFP02238.1 - 0.00016 22.1 0.0 0.00036 21.0 0.0 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family NAPRTase_N PF17767.1 KFP02238.1 - 0.049 14.0 0.0 0.083 13.3 0.0 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DUF16 PF01519.16 KFP02238.1 - 0.057 13.9 0.2 0.13 12.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF1192 PF06698.11 KFP02238.1 - 0.29 11.2 1.5 0.78 9.8 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) TLV_coat PF00429.19 KFP02239.1 - 0.0046 15.7 0.2 0.0048 15.6 0.2 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) AKNA PF12443.8 KFP02239.1 - 0.027 15.1 0.2 0.03 15.0 0.2 1.1 1 0 0 1 1 1 0 AT-hook-containing transcription factor Alpha-amylase_C PF02806.18 KFP02240.1 - 4.4e-14 52.7 0.9 1e-13 51.6 0.4 1.9 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 KFP02240.1 - 3.6e-13 49.8 0.0 5.9e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain LSR PF05624.14 KFP02240.1 - 0.14 12.1 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) RRM_1 PF00076.22 KFP02241.1 - 1.7e-11 43.8 0.3 5e-07 29.5 0.3 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PTCB-BRCT PF12738.7 KFP02242.1 - 1.6e-18 66.4 4.8 6e-17 61.4 0.7 3.5 3 0 0 3 3 3 1 twin BRCT domain BRCT_2 PF16589.5 KFP02242.1 - 1.1e-17 64.2 0.9 3e-08 34.0 0.1 3.6 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KFP02242.1 - 4.4e-17 62.2 4.7 7.2e-05 23.1 0.2 3.9 3 1 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KFP02242.1 - 0.0038 17.5 1.5 0.056 13.7 0.2 2.9 3 0 0 3 3 3 1 DNA ligase 3 BRCT domain Spectrin PF00435.21 KFP02242.1 - 0.0089 16.5 1.5 0.17 12.4 1.8 2.5 1 1 1 2 2 2 1 Spectrin repeat BRCT_3 PF18428.1 KFP02242.1 - 0.014 15.5 6.3 0.95 9.6 0.2 4.0 3 1 1 4 4 4 0 BRCA1 C Terminus (BRCT) domain Pik1 PF11522.8 KFP02242.1 - 0.02 14.8 1.9 0.33 10.9 0.2 3.2 3 0 0 3 3 3 0 Yeast phosphatidylinositol-4-OH kinase Pik1 RTT107_BRCT_5 PF16770.5 KFP02242.1 - 0.05 13.5 0.0 4.4 7.2 0.0 3.2 3 0 0 3 3 3 0 Regulator of Ty1 transposition protein 107 BRCT domain PRKG1_interact PF15898.5 KFP02242.1 - 9.6 7.2 7.5 0.95 10.4 1.8 2.3 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Fibrinogen_C PF00147.18 KFP02243.1 - 4.8e-69 232.5 7.2 7.1e-69 232.0 7.2 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Spc29 PF17082.5 KFP02243.1 - 0.054 13.3 13.7 0.85 9.4 2.7 2.3 1 1 1 2 2 2 0 Spindle Pole Component 29 DUF3601 PF12208.8 KFP02243.1 - 0.11 12.7 0.3 0.64 10.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3601) DUF724 PF05266.14 KFP02243.1 - 2.4 8.0 13.6 2.2 8.1 11.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) SlyX PF04102.12 KFP02243.1 - 2.7 8.7 26.0 0.12 13.0 6.2 3.2 1 1 2 3 3 3 0 SlyX Phage_lysis PF03245.13 KFP02243.1 - 3.9 7.6 12.6 0.052 13.7 4.4 2.0 2 1 0 2 2 2 0 Bacteriophage Rz lysis protein TMPIT PF07851.13 KFP02243.1 - 4.1 6.5 18.1 0.18 11.1 10.0 2.0 1 1 1 2 2 2 0 TMPIT-like protein CENP-H PF05837.12 KFP02243.1 - 7.7 7.0 23.2 0.58 10.6 5.0 2.9 1 1 2 3 3 3 0 Centromere protein H (CENP-H) Herpes_UL6 PF01763.16 KFP02243.1 - 8.4 4.8 15.9 15 4.0 15.8 1.5 1 1 0 1 1 1 0 Herpesvirus UL6 like Acyltransferase PF01553.21 KFP02244.1 - 4.7e-19 68.3 0.0 1e-18 67.3 0.0 1.5 2 0 0 2 2 2 1 Acyltransferase Acyltransf_C PF16076.5 KFP02244.1 - 3e-18 65.7 0.8 6.4e-18 64.6 0.8 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus zf-DNL PF05180.12 KFP02244.1 - 0.1 12.6 0.4 19 5.3 0.1 2.6 2 0 0 2 2 2 0 DNL zinc finger Tmemb_14 PF03647.13 KFP02245.1 - 3.4e-16 59.7 1.8 3.6e-16 59.7 1.8 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Myco_arth_vir_N PF09610.10 KFP02245.1 - 9 6.5 8.1 1.6 8.9 0.8 2.2 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) GST_C_3 PF14497.6 KFP02246.1 - 1.9e-18 66.4 0.0 3.2e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFP02246.1 - 9.1e-18 64.3 0.0 1.5e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFP02246.1 - 2.7e-16 59.7 0.0 4.3e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFP02246.1 - 0.0022 18.0 0.4 0.005 16.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFP02246.1 - 0.0085 16.5 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFP02247.1 - 1.3e-18 67.0 0.0 2.3e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFP02247.1 - 5.5e-17 61.9 0.0 1.2e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFP02247.1 - 3e-14 53.0 0.0 5.5e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFP02247.1 - 0.012 15.6 0.1 0.053 13.5 0.1 2.2 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFP02247.1 - 0.017 15.5 0.0 0.048 14.1 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFP02248.1 - 4.7e-20 71.6 0.0 7.1e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFP02248.1 - 2.4e-18 66.3 0.0 4.7e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFP02248.1 - 7.7e-17 61.3 0.1 1.2e-16 60.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFP02248.1 - 0.0062 16.9 0.0 0.026 14.9 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFP02248.1 - 0.017 15.2 0.0 0.04 13.9 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Sa_NUDIX PF18167.1 KFP02248.1 - 0.055 13.3 0.0 0.24 11.2 0.0 1.8 1 1 1 2 2 2 0 SMODS-associated NUDIX domain Pkinase PF00069.25 KFP02249.1 - 9.9e-79 264.4 0.0 1.3e-78 264.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP02249.1 - 4.5e-37 127.7 0.1 2.1e-36 125.6 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFP02249.1 - 0.00087 18.3 0.1 0.0015 17.6 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Anoct_dimer PF16178.5 KFP02249.1 - 0.005 16.6 0.6 0.01 15.5 0.6 1.4 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin F-box-like PF12937.7 KFP02250.1 - 9.8e-12 44.6 1.4 1.8e-11 43.7 1.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFP02250.1 - 2.2e-08 33.8 1.6 4.1e-08 32.9 1.6 1.5 1 0 0 1 1 1 1 F-box domain MIT PF04212.18 KFP02250.1 - 0.00046 20.2 0.8 0.00083 19.4 0.8 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Xol-1_N PF09108.10 KFP02250.1 - 0.019 14.8 0.1 0.031 14.1 0.1 1.2 1 0 0 1 1 1 0 Switch protein XOL-1, N-terminal GCM PF03615.15 KFP02251.1 - 4.3e-70 234.1 6.0 5.8e-70 233.6 6.0 1.2 1 0 0 1 1 1 1 GCM motif protein ELO PF01151.18 KFP02252.1 - 2.5e-67 227.0 25.4 3.1e-67 226.7 25.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family GCS PF03074.16 KFP02253.1 - 7.2e-181 601.4 0.0 8.7e-181 601.1 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 KFP02253.1 - 0.032 13.6 0.0 0.067 12.5 0.0 1.5 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) SANT_DAMP1_like PF16282.5 KFP02253.1 - 0.067 13.4 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Kelch_1 PF01344.25 KFP02254.1 - 1.1e-46 156.2 13.6 4e-12 45.5 0.0 6.8 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KFP02254.1 - 2.6e-35 119.5 7.3 1.4e-08 34.7 0.2 6.0 2 2 4 6 6 6 5 Kelch motif BACK PF07707.15 KFP02254.1 - 1.1e-25 89.7 0.3 1.1e-25 89.7 0.3 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 KFP02254.1 - 1.5e-22 79.9 0.9 3.5e-22 78.7 0.4 1.8 1 1 1 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 KFP02254.1 - 3e-22 77.7 4.1 1.8e-08 34.0 0.2 6.5 6 1 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 KFP02254.1 - 1.1e-21 76.6 1.4 7e-05 23.0 0.0 5.0 5 0 0 5 5 4 4 Galactose oxidase, central domain Kelch_4 PF13418.6 KFP02254.1 - 8e-19 67.4 0.3 8.3e-05 22.5 0.0 5.8 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP02254.1 - 3.1e-12 46.2 5.9 0.00048 20.1 0.1 5.4 5 0 0 5 5 5 4 Kelch motif Glyoxal_oxid_N PF07250.11 KFP02254.1 - 0.00016 21.0 0.6 0.031 13.5 0.1 2.4 2 1 0 2 2 2 2 Glyoxal oxidase N-terminus DUF1668 PF07893.13 KFP02254.1 - 0.019 14.4 0.0 0.19 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1668) ThiG PF05690.14 KFP02254.1 - 0.081 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG DnaJ PF00226.31 KFP02254.1 - 0.17 12.0 0.0 0.89 9.7 0.0 2.1 2 0 0 2 2 2 0 DnaJ domain LRR_8 PF13855.6 KFP02255.1 - 2.6e-31 107.2 38.4 2.8e-08 33.4 2.6 6.1 2 2 2 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFP02255.1 - 6.7e-28 96.3 46.0 3e-05 24.3 0.0 8.4 6 1 1 8 8 8 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP02255.1 - 6.1e-10 38.9 18.5 0.00021 20.8 2.1 4.8 2 1 3 5 5 5 3 Leucine-rich repeat LRR_1 PF00560.33 KFP02255.1 - 0.022 15.2 40.0 10 7.1 0.1 12.4 9 3 3 12 12 12 0 Leucine Rich Repeat Tropomyosin_1 PF12718.7 KFP02255.1 - 0.054 13.6 3.1 0.14 12.3 3.1 1.6 1 0 0 1 1 1 0 Tropomyosin like DUF2322 PF10084.9 KFP02255.1 - 0.18 11.9 0.4 3.4 7.8 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2322) HMw1_D2 PF18254.1 KFP02255.1 - 0.19 12.1 1.4 3.7 8.0 0.0 3.7 4 1 0 4 4 4 0 HMW1 domain 2 H-kinase_dim PF02895.14 KFP02255.1 - 0.6 10.5 4.8 0.29 11.6 0.2 2.9 3 2 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain LRR_6 PF13516.6 KFP02255.1 - 5.9 7.2 32.1 12 6.2 0.1 9.5 10 0 0 10 10 10 0 Leucine Rich repeat MLIP PF15274.6 KFP02256.1 - 5.5e-113 377.0 5.3 1.2e-112 375.9 5.3 1.6 1 1 0 1 1 1 1 Muscular LMNA-interacting protein Peptidase_C1 PF00112.23 KFP02257.1 - 6e-54 183.4 6.5 6e-54 183.4 6.5 1.7 2 0 0 2 2 2 1 Papain family cysteine protease Pacifastin_I PF05375.13 KFP02257.1 - 0.0004 20.1 3.0 0.0017 18.1 3.0 2.1 1 0 0 1 1 1 1 Pacifastin inhibitor (LCMII) Propeptide_C1 PF08127.13 KFP02257.1 - 0.00066 19.5 0.0 0.0017 18.2 0.0 1.7 1 0 0 1 1 1 1 Peptidase family C1 propeptide Somatomedin_B PF01033.17 KFP02257.1 - 0.027 14.9 17.0 0.027 14.9 17.0 2.4 2 0 0 2 2 2 0 Somatomedin B domain Peptidase_C1_2 PF03051.15 KFP02257.1 - 0.045 12.5 2.8 0.045 12.5 0.8 1.9 3 0 0 3 3 3 0 Peptidase C1-like family FAM83 PF07894.12 KFP02258.1 - 1.9e-106 355.6 0.0 4.3e-106 354.5 0.0 1.6 1 0 0 1 1 1 1 FAM83 A-H PLDc_2 PF13091.6 KFP02258.1 - 1.3e-09 38.0 0.2 2.4e-09 37.2 0.2 1.5 1 0 0 1 1 1 1 PLD-like domain Regulator_TrmB PF11495.8 KFP02258.1 - 0.014 14.6 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB 7tm_1 PF00001.21 KFP02259.1 - 1.3e-57 195.1 21.6 1.7e-57 194.8 21.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Orexin_rec2 PF03827.13 KFP02259.1 - 2.6e-29 101.0 3.1 3.6e-29 100.5 1.5 2.1 2 0 0 2 2 2 1 Orexin receptor type 2 7TM_GPCR_Srsx PF10320.9 KFP02259.1 - 6.6e-05 22.4 20.8 0.00022 20.7 20.8 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP02259.1 - 0.00018 21.3 9.9 0.00018 21.3 9.9 1.8 2 0 0 2 2 2 1 Olfactory receptor GDNF PF02351.16 KFP02260.1 - 2.2e-21 76.6 51.0 1.3e-10 42.0 12.0 3.5 3 1 1 4 4 4 3 GDNF/GAS1 domain HMGL-like PF00682.19 KFP02262.1 - 7e-66 222.5 0.0 8e-66 222.3 0.0 1.0 1 0 0 1 1 1 1 HMGL-like TGFb_propeptide PF00688.18 KFP02263.1 - 1.7e-93 312.9 0.0 2.7e-93 312.2 0.0 1.3 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 KFP02263.1 - 2e-37 128.3 0.6 5.6e-37 126.9 0.5 1.8 2 0 0 2 2 2 1 Transforming growth factor beta like domain YkuD_2 PF13645.6 KFP02263.1 - 0.093 12.2 1.1 0.2 11.1 0.2 1.9 2 0 0 2 2 2 0 L,D-transpeptidase catalytic domain Spectrin PF00435.21 KFP02264.1 - 3e-228 741.2 482.9 1.3e-16 61.0 7.0 42.5 39 4 4 44 44 42 33 Spectrin repeat CH PF00307.31 KFP02264.1 - 2.1e-39 134.1 1.3 1.7e-19 70.0 0.0 5.7 4 0 0 4 4 3 2 Calponin homology (CH) domain GAS2 PF02187.17 KFP02264.1 - 2.7e-30 104.3 0.4 1.1e-29 102.3 0.4 2.2 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Spectrin_like PF18373.1 KFP02264.1 - 9.2e-30 102.6 0.7 9.2e-30 102.6 0.7 9.5 10 0 0 10 10 8 1 Spectrin like domain SH3_10 PF17902.1 KFP02264.1 - 2.8e-20 72.1 0.2 1.1e-19 70.3 0.2 2.1 1 0 0 1 1 1 1 SH3 domain EF-hand_1 PF00036.32 KFP02264.1 - 8.5e-12 43.7 2.3 0.0001 21.6 0.8 3.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFP02264.1 - 7.8e-11 42.3 5.0 1.2e-09 38.5 1.0 5.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP02264.1 - 7.8e-11 41.0 1.6 0.00037 20.2 0.4 3.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFP02264.1 - 1.3e-07 30.8 4.5 5e-05 22.6 1.1 3.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFP02264.1 - 6e-07 29.2 6.5 3.4e-06 26.8 0.1 4.4 4 1 1 5 5 4 2 EF-hand domain pair CAMSAP_CH PF11971.8 KFP02264.1 - 3.5e-06 26.8 0.3 0.0054 16.5 0.0 3.7 3 0 0 3 3 3 2 CAMSAP CH domain Laminin_II PF06009.12 KFP02264.1 - 0.006 16.6 0.3 0.006 16.6 0.3 30.9 23 8 6 35 35 33 3 Laminin Domain II HTH_57 PF18679.1 KFP02264.1 - 0.034 14.5 1.7 1.9 8.8 1.7 4.5 1 0 0 1 1 1 0 ThcOx helix turn helix domain GCSF PF16647.5 KFP02264.1 - 0.078 12.8 0.7 0.23 11.3 0.0 2.2 2 0 0 2 2 2 0 Granulocyte colony-stimulating factor DUF5304 PF17230.2 KFP02264.1 - 3.8 7.7 13.6 1 9.6 0.4 6.7 5 0 0 5 5 5 0 Family of unknown function (DUF5304) Scm3 PF10384.9 KFP02264.1 - 7.3 6.4 8.6 1.4 8.8 0.2 4.6 5 0 0 5 5 4 0 Centromere protein Scm3 BEN PF10523.9 KFP02266.1 - 9.9e-13 48.1 0.0 2e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 BEN domain DUF1087 PF06465.13 KFP02266.1 - 0.052 13.6 0.5 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) bZIP_2 PF07716.15 KFP02266.1 - 0.17 12.0 0.3 0.17 12.0 0.3 1.8 2 0 0 2 2 2 0 Basic region leucine zipper PIN_11 PF18479.1 KFP02267.1 - 1.8e-63 212.0 1.1 8e-63 209.9 0.0 2.6 3 0 0 3 3 3 1 PIN like domain zf-C2H2_4 PF13894.6 KFP02267.1 - 0.0031 18.2 86.7 0.41 11.6 0.8 13.4 15 0 0 15 15 15 7 C2H2-type zinc finger zf-DBF PF07535.12 KFP02267.1 - 0.0034 17.5 0.9 0.0034 17.5 0.9 6.2 7 1 1 8 8 8 1 DBF zinc finger zf_C2H2_10 PF18414.1 KFP02267.1 - 0.73 9.4 7.8 15 5.2 4.1 4.0 3 0 0 3 3 3 0 C2H2 type zinc-finger DUF4347 PF14252.6 KFP02268.1 - 0.096 12.5 0.1 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4347) Ras PF00071.22 KFP02269.1 - 1.4e-53 180.8 1.4 2.1e-53 180.3 1.4 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP02269.1 - 2.8e-33 114.7 0.8 4.5e-33 114.0 0.3 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP02269.1 - 2.6e-10 40.0 0.9 3.5e-10 39.6 0.9 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP02269.1 - 9.4e-07 28.9 0.1 2e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP02269.1 - 0.0001 22.3 2.5 0.013 15.4 0.2 2.3 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFP02269.1 - 0.00011 21.8 0.5 0.00019 21.1 0.5 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFP02269.1 - 0.00044 19.7 0.2 0.00061 19.2 0.2 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 KFP02269.1 - 0.0085 15.0 1.5 1 8.1 0.1 2.2 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) ATP_bind_1 PF03029.17 KFP02269.1 - 0.0088 15.9 4.3 0.012 15.4 0.9 2.3 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 KFP02269.1 - 0.013 15.1 0.2 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B YwhD PF08741.10 KFP02269.1 - 0.02 14.6 0.1 0.031 14.0 0.1 1.4 1 0 0 1 1 1 0 YwhD family MMR_HSR1_Xtn PF16897.5 KFP02269.1 - 0.071 13.1 0.4 0.18 11.9 0.4 1.6 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DNA_primase_lrg PF04104.14 KFP02270.1 - 2.8e-94 315.5 0.0 5.3e-94 314.6 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Syntaxin PF00804.25 KFP02270.1 - 0.16 11.6 0.9 0.38 10.4 0.1 1.8 2 0 0 2 2 2 0 Syntaxin 7tm_2 PF00002.24 KFP02271.1 - 6.4e-78 261.4 8.4 7.9e-78 261.1 8.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF1129 PF06570.11 KFP02271.1 - 0.099 12.1 2.4 0.2 11.1 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Condensin2nSMC PF12422.8 KFP02272.1 - 2.2e-56 190.2 1.1 2.2e-56 190.2 1.1 3.8 4 1 0 4 4 4 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.22 KFP02272.1 - 1.5e-08 34.2 1.3 3 8.3 0.0 5.9 6 0 0 6 6 5 3 HEAT repeat Cnd1 PF12717.7 KFP02272.1 - 1.2e-05 25.4 1.5 0.073 13.1 0.0 4.3 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFP02272.1 - 0.00039 20.7 0.0 1 9.8 0.0 3.1 2 1 0 2 2 2 2 HEAT repeats Adaptin_N PF01602.20 KFP02272.1 - 0.00048 18.8 1.3 0.00095 17.8 0.1 2.2 2 1 0 2 2 2 1 Adaptin N terminal region DUF577 PF04510.12 KFP02272.1 - 0.0024 17.8 3.1 0.27 11.1 0.0 4.0 4 0 0 4 4 4 1 Family of unknown function (DUF577) DUF5389 PF17364.2 KFP02272.1 - 0.0073 16.3 0.0 0.029 14.4 0.0 2.0 1 0 0 1 1 1 1 Family of unknown function (DUF5389) TIP120 PF08623.10 KFP02272.1 - 0.037 13.8 2.2 0.12 12.1 0.0 2.9 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) Vac14_Fab1_bd PF12755.7 KFP02272.1 - 0.039 14.6 0.1 1.2 9.8 0.0 3.5 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Tautomerase PF01361.21 KFP02272.1 - 0.054 13.4 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 Tautomerase enzyme PPR PF01535.20 KFP02272.1 - 0.14 12.5 0.0 0.57 10.6 0.0 2.1 1 0 0 1 1 1 0 PPR repeat Y_phosphatase PF00102.27 KFP02274.1 - 5e-73 245.5 0.4 7e-73 245.1 0.4 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFP02274.1 - 0.001 18.9 0.0 0.0023 17.7 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFP02274.1 - 0.15 12.2 0.6 3.2 7.8 0.0 2.6 3 0 0 3 3 3 0 Inositol hexakisphosphate DnaJ PF00226.31 KFP02275.1 - 3.2e-29 100.8 4.2 5.5e-29 100.1 4.2 1.4 1 0 0 1 1 1 1 DnaJ domain DUF5064 PF16703.5 KFP02275.1 - 0.084 13.4 0.1 0.26 11.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5064) HECT PF00632.25 KFP02276.1 - 2.1e-96 323.0 0.0 3.5e-96 322.3 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KFP02276.1 - 0.00037 20.0 0.1 0.00096 18.8 0.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Homeodomain PF00046.29 KFP02277.1 - 4.7e-23 80.8 6.8 6.4e-23 80.4 6.8 1.2 1 0 0 1 1 1 1 Homeodomain QLQ PF08880.11 KFP02277.1 - 0.00018 21.2 0.4 0.00018 21.2 0.4 1.7 2 0 0 2 2 2 1 QLQ MA3 PF02847.17 KFP02278.1 - 2.2e-27 95.3 1.2 1.1e-26 93.0 1.2 2.3 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 KFP02278.1 - 1.6e-21 76.9 5.6 1.6e-21 76.9 5.6 2.3 2 1 0 2 2 2 1 MIF4G domain LMBR1 PF04791.16 KFP02279.1 - 3.3e-92 310.0 25.8 5.3e-56 190.6 13.7 2.0 1 1 1 2 2 2 2 LMBR1-like membrane protein Orf78 PF06024.12 KFP02279.1 - 0.072 13.4 0.2 0.072 13.4 0.2 3.5 4 0 0 4 4 4 0 Orf78 (ac78) Sigma_reg_N PF13800.6 KFP02279.1 - 0.1 12.9 0.1 0.1 12.9 0.1 4.3 5 1 0 5 5 5 0 Sigma factor regulator N-terminal RRM_1 PF00076.22 KFP02280.1 - 0.007 16.2 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP02280.1 - 0.036 13.9 0.1 0.41 10.5 0.1 2.5 3 0 0 3 3 3 0 Occluded RNA-recognition motif RRM_3 PF08777.11 KFP02280.1 - 1.3 9.1 0.0 1.3 9.1 0.0 4.2 5 0 0 5 5 5 0 RNA binding motif DUF3456 PF11938.8 KFP02281.1 - 0.00013 22.5 0.4 0.00015 22.4 0.4 1.0 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP SapB_2 PF03489.17 KFP02281.1 - 0.058 13.5 0.1 0.073 13.2 0.1 1.2 1 0 0 1 1 1 0 Saposin-like type B, region 2 INSIG PF07281.12 KFP02282.1 - 2.8e-37 128.4 4.5 3e-36 125.1 4.5 2.1 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) 7tm_1 PF00001.21 KFP02283.1 - 5.5e-73 245.5 9.4 7.6e-73 245.1 9.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP02283.1 - 5.2e-07 29.6 5.5 1.1e-06 28.4 5.5 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP02283.1 - 0.001 18.9 1.0 0.003 17.3 0.8 1.8 2 0 0 2 2 2 1 Olfactory receptor OppC_N PF12911.7 KFP02283.1 - 0.042 13.8 0.3 0.042 13.8 0.3 2.9 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C PTCB-BRCT PF12738.7 KFP02285.1 - 4.5e-55 183.5 2.7 7.4e-21 73.9 0.0 4.7 4 0 0 4 4 4 4 twin BRCT domain BRCT PF00533.26 KFP02285.1 - 5.7e-51 170.8 0.3 2.9e-13 50.0 0.0 6.0 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KFP02285.1 - 2e-31 108.2 0.2 6.9e-07 29.6 0.0 6.1 6 0 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KFP02285.1 - 6.4e-25 87.0 4.2 2.3e-20 72.3 0.1 4.1 4 0 0 4 4 4 2 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 KFP02285.1 - 2.9e-13 49.9 3.0 0.00038 20.7 0.0 5.8 5 1 0 5 5 5 3 DNA ligase 3 BRCT domain DPPIV_N PF00930.21 KFP02286.1 - 4.1e-110 367.9 0.3 6e-110 367.3 0.3 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KFP02286.1 - 6.6e-37 127.0 0.1 1.1e-36 126.3 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 KFP02286.1 - 5.2e-07 29.4 0.0 0.029 14.3 0.0 3.6 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat DLH PF01738.18 KFP02286.1 - 1.8e-05 24.4 0.5 7.5e-05 22.4 0.5 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family A_deaminase PF00962.22 KFP02287.1 - 8.7e-20 71.3 0.0 1.6e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 KFP02287.1 - 5.1e-17 62.0 0.1 1.6e-16 60.4 0.0 1.8 2 0 0 2 2 2 1 Adenosine/AMP deaminase N-terminal Nrap_D2 PF17403.2 KFP02287.1 - 0.048 13.4 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Hydrolase_like PF13242.6 KFP02288.1 - 2.9e-09 36.9 0.0 1e-08 35.1 0.0 1.9 1 1 0 1 1 1 1 HAD-hyrolase-like FNIP_C PF14638.6 KFP02288.1 - 0.078 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus Hydrolase_6 PF13344.6 KFP02288.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase IL17R_fnIII_D1 PF16556.5 KFP02289.1 - 9.5e-61 203.9 0.3 2.1e-60 202.8 0.3 1.6 1 0 0 1 1 1 1 Interleukin-17 receptor, fibronectin-III-like domain 1 SEFIR PF08357.11 KFP02289.1 - 1.1e-42 145.8 0.7 2.1e-42 144.9 0.0 1.8 2 0 0 2 2 2 1 SEFIR domain IL17R_fnIII_D2 PF16578.5 KFP02289.1 - 3.8e-38 130.2 0.7 3.8e-38 130.2 0.7 2.3 2 0 0 2 2 2 1 Interleukin 17 receptor D Adeno_terminal PF02459.15 KFP02289.1 - 1.3 7.4 3.9 1.9 6.8 3.9 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein DCP1 PF06058.13 KFP02290.1 - 3.6e-28 97.8 0.1 9.2e-28 96.5 0.0 1.8 2 0 0 2 2 2 1 Dcp1-like decapping family mRNA_decap_C PF16741.5 KFP02290.1 - 7.6e-20 70.0 1.1 1.5e-19 69.0 1.1 1.5 1 0 0 1 1 1 1 mRNA-decapping enzyme C-terminus wnt PF00110.19 KFP02291.1 - 6.7e-121 403.6 23.0 7.6e-121 403.4 23.0 1.0 1 0 0 1 1 1 1 wnt family LRR_6 PF13516.6 KFP02292.1 - 2.7e-22 76.9 44.3 0.00028 20.7 0.2 11.4 12 0 0 12 12 12 8 Leucine Rich repeat LRR_4 PF12799.7 KFP02292.1 - 2.7e-17 62.6 18.3 0.0069 16.8 1.5 7.0 5 2 2 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP02292.1 - 0.0005 19.8 24.3 4.2 7.2 2.5 7.6 3 2 2 6 6 6 2 Leucine rich repeat LRR_1 PF00560.33 KFP02292.1 - 0.00098 19.4 40.0 11 7.1 1.1 10.3 9 3 0 9 9 9 1 Leucine Rich Repeat SAM_Ste50p PF09235.10 KFP02292.1 - 0.0027 17.9 4.5 0.25 11.6 0.3 4.4 4 1 1 5 5 5 1 Ste50p, sterile alpha motif LRR_2 PF07723.13 KFP02292.1 - 0.059 14.1 8.8 20 6.0 0.1 6.1 6 0 0 6 6 6 0 Leucine Rich Repeat Bac_DnaA_C PF08299.11 KFP02292.1 - 0.12 12.4 0.0 0.94 9.6 0.0 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein helix-turn-helix Cast PF10174.9 KFP02293.1 - 0 1076.7 147.3 0 1076.5 147.3 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone PKcGMP_CC PF16808.5 KFP02293.1 - 0.0022 17.8 0.6 0.0022 17.8 0.6 12.8 13 3 3 16 16 16 4 Coiled-coil N-terminus of cGMP-dependent protein kinase Spc7 PF08317.11 KFP02293.1 - 0.0024 16.8 17.3 0.0024 16.8 17.3 7.6 1 1 7 8 8 8 4 Spc7 kinetochore protein Fib_alpha PF08702.10 KFP02293.1 - 0.01 16.0 12.0 0.01 16.0 12.0 8.5 1 1 4 8 8 8 0 Fibrinogen alpha/beta chain family DUF5486 PF17588.2 KFP02293.1 - 0.78 9.7 6.2 0.12 12.3 0.4 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5486) Phage_tail_NK PF16532.5 KFP02293.1 - 5.3 6.6 7.8 8 6.0 0.5 3.5 3 0 0 3 3 3 0 Sf6-type phage tail needle knob or tip of some Caudovirales Ninjurin PF04923.12 KFP02294.1 - 2.3e-35 120.6 10.4 2.6e-35 120.5 10.4 1.0 1 0 0 1 1 1 1 Ninjurin DUF1418 PF07214.12 KFP02294.1 - 0.072 13.0 2.9 0.12 12.2 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) FixS PF03597.15 KFP02294.1 - 4.8 7.0 8.9 0.59 9.9 1.1 2.3 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Ninjurin PF04923.12 KFP02295.1 - 2.3e-35 120.6 10.4 2.6e-35 120.5 10.4 1.0 1 0 0 1 1 1 1 Ninjurin DUF1418 PF07214.12 KFP02295.1 - 0.072 13.0 2.9 0.12 12.2 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) FixS PF03597.15 KFP02295.1 - 4.8 7.0 8.9 0.59 9.9 1.1 2.3 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type CHGN PF05679.16 KFP02296.1 - 6.1e-25 88.0 0.0 2.6e-24 85.9 0.0 1.9 1 1 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 KFP02296.1 - 2.4e-12 46.3 0.7 5.4e-12 45.2 0.7 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase PA14 PF07691.12 KFP02296.1 - 5e-06 26.4 0.0 1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Glycos_transf_2 PF00535.26 KFP02296.1 - 0.00034 20.5 0.0 0.00067 19.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 GLEYA PF10528.9 KFP02296.1 - 0.035 14.5 0.0 0.069 13.6 0.0 1.5 1 0 0 1 1 1 0 GLEYA domain CENP-B_dimeris PF09026.10 KFP02296.1 - 0.31 11.4 2.9 0.76 10.2 2.9 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SNF PF00209.18 KFP02297.1 - 9.4e-246 816.5 35.4 1.1e-245 816.3 35.4 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 KFP02298.1 - 1.2e-244 812.8 36.6 1.4e-244 812.6 36.6 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 KFP02299.1 - 7.8e-229 760.7 41.2 9e-229 760.5 41.2 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Sec7 PF01369.20 KFP02300.1 - 6.5e-62 208.5 0.0 1.5e-61 207.2 0.0 1.7 1 0 0 1 1 1 1 Sec7 domain IQ_SEC7_PH PF16453.5 KFP02300.1 - 1.3e-61 206.6 2.9 2e-61 206.0 0.9 2.2 2 0 0 2 2 2 1 PH domain AAA_35 PF14516.6 KFP02300.1 - 0.023 13.5 0.0 0.044 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain IQ PF00612.27 KFP02300.1 - 0.39 10.6 2.2 0.51 10.3 0.3 2.2 2 0 0 2 2 2 0 IQ calmodulin-binding motif WASH_WAHD PF11945.8 KFP02301.1 - 9.2e-125 416.0 0.4 1.3e-124 415.5 0.4 1.2 1 0 0 1 1 1 1 WAHD domain of WASH complex FliD_N PF02465.18 KFP02301.1 - 0.11 13.2 0.4 3.7 8.3 0.2 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Helicase_C_2 PF13307.6 KFP02302.1 - 3.6e-57 193.3 0.7 1.7e-56 191.1 0.0 2.6 4 0 0 4 4 4 1 Helicase C-terminal domain DEAD_2 PF06733.15 KFP02302.1 - 3.3e-54 183.2 0.7 7.9e-54 181.9 0.7 1.7 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 KFP02302.1 - 0.16 12.0 0.6 1 9.4 0.6 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit zf-H2C2_2 PF13465.6 KFP02303.1 - 2.1e-51 170.1 43.4 1.3e-10 41.2 0.4 6.9 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFP02303.1 - 4.7e-46 152.8 51.2 5e-08 33.0 1.9 7.1 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP02303.1 - 1.3e-27 94.1 46.3 2.8e-05 24.6 0.9 7.1 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP02303.1 - 1.1e-14 54.3 22.6 0.0062 16.8 0.1 6.4 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP02303.1 - 3.4e-14 52.4 43.8 2.3e-05 24.2 0.9 7.1 7 0 0 7 7 7 5 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFP02303.1 - 2.6e-09 37.0 25.1 0.0018 18.3 2.6 4.7 2 1 3 5 5 5 5 Zinc ribbon domain zf_UBZ PF18439.1 KFP02303.1 - 3.9e-09 35.9 21.3 0.27 10.9 0.0 6.2 6 0 0 6 6 6 4 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 KFP02303.1 - 2.8e-08 33.9 39.2 0.4 11.1 0.5 7.0 7 0 0 7 7 7 5 Zinc-finger of C2H2 type XPA_N PF01286.18 KFP02303.1 - 5.3e-08 32.8 23.1 0.076 13.1 0.6 6.1 6 0 0 6 6 6 2 XPA protein N-terminal zinc_ribbon_15 PF17032.5 KFP02303.1 - 8.5e-07 29.6 19.4 0.027 15.2 4.3 3.1 1 1 2 3 3 3 3 zinc-ribbon family CpXC PF14353.6 KFP02303.1 - 0.0004 20.4 18.2 0.42 10.7 0.2 5.8 3 2 1 5 5 5 1 CpXC protein LIM PF00412.22 KFP02303.1 - 0.00054 20.1 21.9 0.065 13.5 5.0 4.6 2 2 2 4 4 4 1 LIM domain DUF2072 PF09845.9 KFP02303.1 - 0.00072 19.8 21.7 0.51 10.6 0.3 5.5 4 2 2 6 6 6 1 Zn-ribbon containing protein zf-LYAR PF08790.11 KFP02303.1 - 0.0015 18.4 24.7 0.95 9.4 0.2 6.5 7 0 0 7 7 6 2 LYAR-type C2HC zinc finger zf_C2H2_13 PF18508.1 KFP02303.1 - 0.0021 17.6 6.3 8.4 6.1 0.0 4.8 5 0 0 5 5 5 0 Zinc finger domain HypA PF01155.19 KFP02303.1 - 0.0023 17.9 18.2 0.43 10.6 0.8 3.5 1 1 2 3 3 3 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Yippee-Mis18 PF03226.14 KFP02303.1 - 0.0026 17.9 16.6 2.7 8.3 1.8 4.4 3 2 0 3 3 3 2 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2256 PF10013.9 KFP02303.1 - 0.0053 16.9 14.0 17 5.6 0.1 6.0 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) DNA_RNApol_7kD PF03604.13 KFP02303.1 - 0.006 16.2 17.1 12 5.6 0.2 5.9 6 0 0 6 6 6 0 DNA directed RNA polymerase, 7 kDa subunit Zn_Tnp_IS1595 PF12760.7 KFP02303.1 - 0.0062 16.5 29.8 0.59 10.1 1.0 5.2 4 1 2 6 6 6 2 Transposase zinc-ribbon domain YhfH PF14149.6 KFP02303.1 - 0.0072 16.3 17.7 2.7 8.1 0.2 5.2 5 0 0 5 5 5 1 YhfH-like protein zf-C2H2_11 PF16622.5 KFP02303.1 - 0.0072 16.1 34.3 1.3 8.8 0.4 6.6 7 0 0 7 7 6 2 zinc-finger C2H2-type Zn_ribbon_SprT PF17283.2 KFP02303.1 - 0.0081 16.0 0.4 0.0081 16.0 0.4 4.7 3 3 1 4 4 4 1 SprT-like zinc ribbon domain zf-AN1 PF01428.16 KFP02303.1 - 0.01 15.9 28.6 6.6 7.0 0.2 6.3 5 1 1 6 6 6 0 AN1-like Zinc finger C1_4 PF07975.12 KFP02303.1 - 0.019 15.2 25.5 0.081 13.2 5.6 4.5 1 1 5 6 6 6 0 TFIIH C1-like domain GAGA PF09237.11 KFP02303.1 - 0.022 14.6 14.8 1.2 9.0 0.0 4.3 1 1 3 5 5 5 0 GAGA factor FYDLN_acid PF09538.10 KFP02303.1 - 0.023 15.3 15.5 8.2 7.2 1.9 5.4 1 1 4 5 5 5 0 Protein of unknown function (FYDLN_acid) TFIIS_C PF01096.18 KFP02303.1 - 0.024 14.5 27.1 1.1 9.1 0.4 6.0 6 0 0 6 6 6 0 Transcription factor S-II (TFIIS) zf-C2HC_2 PF13913.6 KFP02303.1 - 0.04 13.8 18.8 0.68 9.9 0.1 5.6 5 0 0 5 5 5 0 zinc-finger of a C2HC-type Zn_ribbon_recom PF13408.6 KFP02303.1 - 0.046 14.2 20.8 0.42 11.2 0.5 4.8 2 2 2 4 4 4 0 Recombinase zinc beta ribbon domain DUF3268 PF11672.8 KFP02303.1 - 0.047 14.0 14.8 2.2 8.6 0.8 4.0 1 1 1 4 4 4 0 zinc-finger-containing domain OSTMP1 PF09777.9 KFP02303.1 - 0.054 12.9 9.9 0.16 11.4 9.9 1.7 1 1 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor Baculo_IE-1 PF05290.11 KFP02303.1 - 0.059 13.3 8.8 7.9 6.4 0.1 3.9 1 1 1 3 3 3 0 Baculovirus immediate-early protein (IE-0) HalOD2 PF18547.1 KFP02303.1 - 0.065 13.1 17.2 0.38 10.7 1.2 4.1 3 2 1 4 4 3 0 Halobacterial output domain 2 zf-C2H2_2 PF12756.7 KFP02303.1 - 0.079 13.3 27.9 0.45 10.9 0.4 5.4 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) GF_recep_IV PF14843.6 KFP02303.1 - 0.091 12.6 20.2 0.11 12.3 7.7 2.2 1 1 1 2 2 2 0 Growth factor receptor domain IV zinc-ribbons_6 PF07191.12 KFP02303.1 - 0.1 12.6 25.4 1.3 9.0 6.4 4.7 1 1 1 2 2 1 0 zinc-ribbons Zn-C2H2_12 PF18112.1 KFP02303.1 - 0.15 12.5 0.0 0.15 12.5 0.0 5.5 6 0 0 6 6 5 0 Autophagy receptor zinc finger-C2H2 domain MBD PF01429.19 KFP02303.1 - 0.17 11.6 2.3 7.4 6.4 2.3 3.4 1 1 1 2 2 2 0 Methyl-CpG binding domain ADK_lid PF05191.14 KFP02303.1 - 0.19 11.8 13.3 3.7 7.6 1.0 4.5 3 1 0 3 3 3 0 Adenylate kinase, active site lid zf-trcl PF13451.6 KFP02303.1 - 0.36 10.8 21.1 18 5.3 0.1 5.9 6 0 0 6 6 6 0 Probable zinc-ribbon domain HNH PF01844.23 KFP02303.1 - 0.38 11.0 29.0 4 7.7 0.4 6.7 7 0 0 7 7 7 0 HNH endonuclease zf-ribbon_3 PF13248.6 KFP02303.1 - 0.53 9.8 15.0 3 7.4 0.2 4.9 5 0 0 5 5 5 0 zinc-ribbon domain zf-C2HE PF16278.5 KFP02303.1 - 1.2 9.7 30.9 6.3 7.3 0.8 5.9 2 2 2 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger BolA PF01722.18 KFP02303.1 - 1.2 9.4 17.5 18 5.7 0.1 4.3 2 1 1 3 3 3 0 BolA-like protein zinc_ribbon_9 PF14369.6 KFP02303.1 - 1.3 9.4 19.3 1.9 8.8 0.1 5.7 5 1 1 6 6 6 0 zinc-ribbon DUF899 PF05988.12 KFP02303.1 - 2.1 7.8 6.4 3.7 7.0 0.3 3.0 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF899) CxC7 PF18866.1 KFP02303.1 - 5 7.3 17.7 6 7.1 0.2 5.1 1 1 5 6 6 6 0 CxC7 like cysteine cluster associated with KDZ transposases zf-RING_5 PF14634.6 KFP02303.1 - 6.7 6.8 26.4 4.8 7.2 6.5 4.6 2 2 1 3 3 3 0 zinc-RING finger domain zf-Paramyx-P PF13008.7 KFP02303.1 - 8.1 6.0 19.9 17 5.0 0.1 5.5 6 0 0 6 6 6 0 Zinc-binding domain of Paramyxoviridae V protein PBP_sp32 PF07222.12 KFP02304.1 - 1.9e-30 106.2 0.4 2e-30 106.1 0.4 1.0 1 0 0 1 1 1 1 Proacrosin binding protein sp32 IBN_N PF03810.19 KFP02305.1 - 5.3e-19 67.9 0.0 1.1e-16 60.5 0.0 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 KFP02305.1 - 3.2e-09 36.1 3.6 3.2e-09 36.1 3.6 3.0 2 1 0 3 3 3 1 Cse1 DUF1539 PF07560.11 KFP02305.1 - 0.028 14.5 3.9 0.22 11.6 0.0 3.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) Cwf_Cwc_15 PF04889.12 KFP02305.1 - 0.097 12.4 5.1 0.19 11.4 5.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RTP1_C1 PF10363.9 KFP02305.1 - 0.14 12.4 1.6 4 7.7 0.1 3.6 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Xpo1 PF08389.12 KFP02305.1 - 0.16 12.1 12.6 0.089 12.8 0.7 4.3 4 1 0 4 4 4 0 Exportin 1-like protein FYDLN_acid PF09538.10 KFP02305.1 - 0.25 12.0 3.8 0.62 10.8 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF5367 PF17329.2 KFP02305.1 - 0.27 11.4 1.4 2.8 8.1 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5367) BUD22 PF09073.10 KFP02305.1 - 0.31 10.3 3.7 0.62 9.3 3.7 1.4 1 0 0 1 1 1 0 BUD22 BSP_II PF05432.11 KFP02305.1 - 1.4 8.6 12.1 2.2 7.9 12.1 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TT_ORF2 PF02957.15 KFP02305.1 - 2 9.3 8.6 4.4 8.2 8.6 1.5 1 0 0 1 1 1 0 TT viral ORF2 Caprin-1_C PF12287.8 KFP02306.1 - 3.9e-120 402.0 28.2 3.9e-120 402.0 28.2 3.2 3 1 1 4 4 4 1 Cytoplasmic activation/proliferation-associated protein-1 C term Caprin-1_dimer PF18293.1 KFP02306.1 - 1.7e-39 134.9 0.3 4.4e-39 133.6 0.3 1.8 1 0 0 1 1 1 1 Caprin-1 dimerization domain C1q PF00386.21 KFP02306.1 - 4.5e-33 114.2 0.0 9.1e-33 113.2 0.0 1.6 1 0 0 1 1 1 1 C1q domain DUF1460 PF07313.12 KFP02306.1 - 0.068 12.6 0.3 0.13 11.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) FAM60A PF15396.6 KFP02307.1 - 7.1e-83 277.8 10.3 9e-83 277.4 10.3 1.1 1 0 0 1 1 1 1 Protein Family FAM60A DENN PF02141.21 KFP02308.1 - 6.2e-63 212.1 6.3 1.5e-62 210.9 3.8 2.4 2 0 0 2 2 2 1 DENN (AEX-3) domain RUN PF02759.19 KFP02308.1 - 5.9e-41 139.6 5.2 3.2e-20 72.5 3.4 3.0 3 0 0 3 3 3 2 RUN domain dDENN PF03455.19 KFP02308.1 - 6.3e-18 64.5 2.9 6.3e-18 64.5 2.9 2.5 2 0 0 2 2 2 1 dDENN domain uDENN PF03456.18 KFP02308.1 - 5.6e-14 52.6 0.0 1.6e-13 51.2 0.0 1.9 1 0 0 1 1 1 1 uDENN domain PLAT PF01477.23 KFP02308.1 - 4.3e-12 46.6 0.0 8.7e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain PrmA PF06325.13 KFP02309.1 - 1.6e-10 40.9 0.1 2.3e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KFP02309.1 - 2.8e-09 37.0 0.0 8e-09 35.5 0.0 1.7 1 1 0 1 1 1 1 Lysine methyltransferase Met_10 PF02475.16 KFP02309.1 - 0.00022 21.0 0.0 0.00031 20.5 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 KFP02309.1 - 0.0056 16.2 0.0 0.0079 15.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 KFP02309.1 - 0.081 12.6 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 KFP02309.1 - 0.11 13.2 0.0 0.2 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KFP02309.1 - 0.22 11.2 0.0 0.3 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) LRR_6 PF13516.6 KFP02310.1 - 6.9e-13 47.5 6.1 0.042 13.9 0.0 7.1 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.7 KFP02310.1 - 2e-06 28.0 2.3 0.0029 18.0 0.1 4.3 3 1 3 6 6 6 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP02310.1 - 0.0026 18.1 3.9 46 5.1 0.0 5.2 4 1 0 4 4 4 1 Leucine Rich Repeat DUF4617 PF15395.6 KFP02311.1 - 3.8e-280 932.8 115.9 3.8e-280 932.8 115.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4617) BicD PF09730.9 KFP02312.1 - 0 1144.2 64.7 0 1144.2 64.7 1.9 2 0 0 2 2 2 1 Microtubule-associated protein Bicaudal-D Bap31_Bap29_C PF18035.1 KFP02312.1 - 0.00011 22.1 4.3 0.00011 22.1 4.3 8.7 8 2 0 8 8 8 1 Bap31/Bap29 cytoplasmic coiled-coil domain Med4 PF10018.9 KFP02312.1 - 0.0015 18.3 1.3 0.0015 18.3 1.3 5.6 5 2 1 6 6 6 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF1759 PF03564.15 KFP02312.1 - 0.0032 17.4 5.9 0.0032 17.4 5.9 5.8 5 2 1 6 6 6 1 Protein of unknown function (DUF1759) ADIP PF11559.8 KFP02312.1 - 0.0056 16.8 5.8 0.0056 16.8 5.8 7.4 4 2 2 8 8 8 2 Afadin- and alpha -actinin-Binding HALZ PF02183.18 KFP02312.1 - 0.011 15.9 2.4 0.011 15.9 2.4 9.2 8 1 1 9 9 9 0 Homeobox associated leucine zipper ApoO PF09769.9 KFP02312.1 - 2.7 8.0 16.7 0.15 12.0 0.7 4.6 4 2 0 4 4 4 0 Apolipoprotein O Spc7 PF08317.11 KFP02312.1 - 2.9 6.7 96.8 0.39 9.6 4.4 6.2 4 2 1 5 5 5 0 Spc7 kinetochore protein RhoGEF PF00621.20 KFP02313.1 - 1.9e-46 158.6 0.5 1.9e-46 158.6 0.5 1.7 2 0 0 2 2 1 1 RhoGEF domain PH PF00169.29 KFP02313.1 - 1e-25 90.2 0.3 1.4e-12 48.1 0.0 3.3 2 1 1 3 3 3 2 PH domain FYVE PF01363.21 KFP02313.1 - 6e-18 64.8 11.4 1.7e-17 63.3 11.4 1.8 1 0 0 1 1 1 1 FYVE zinc finger IQ_SEC7_PH PF16453.5 KFP02313.1 - 6e-08 32.8 0.4 1.2e-06 28.5 0.3 2.4 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 KFP02313.1 - 7.5e-05 22.6 8.1 0.013 15.4 3.0 3.9 3 1 0 3 3 3 1 Pleckstrin homology domain PH_6 PF15406.6 KFP02313.1 - 0.00071 19.8 0.0 1.5 9.1 0.0 2.7 2 0 0 2 2 2 2 Pleckstrin homology domain FYVE_2 PF02318.16 KFP02313.1 - 0.0015 18.8 11.6 0.0052 17.0 11.0 2.3 1 1 0 1 1 1 1 FYVE-type zinc finger PH_11 PF15413.6 KFP02313.1 - 0.0032 17.9 1.2 1.3 9.5 0.0 3.8 3 1 0 3 3 2 1 Pleckstrin homology domain PH_2 PF08458.10 KFP02313.1 - 0.0054 17.1 0.1 0.81 10.1 0.1 2.8 2 0 0 2 2 2 1 Plant pleckstrin homology-like region Presenilin PF01080.17 KFP02313.1 - 0.019 13.8 1.7 0.033 13.0 1.7 1.3 1 0 0 1 1 1 0 Presenilin PH_5 PF15405.6 KFP02313.1 - 0.073 13.2 0.2 8.8 6.4 0.1 3.1 1 1 1 2 2 2 0 Pleckstrin homology domain zf-RING_UBOX PF13445.6 KFP02313.1 - 0.2 11.7 6.9 0.71 9.9 6.9 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 KFP02313.1 - 0.24 11.4 12.7 0.54 10.3 12.7 1.7 1 0 0 1 1 1 0 zinc-RING finger domain PH_16 PF17838.1 KFP02313.1 - 0.24 11.2 2.1 3.4 7.5 0.1 2.8 3 0 0 3 3 3 0 PH domain DUF4162 PF13732.6 KFP02313.1 - 0.55 11.0 4.8 3.2 8.5 0.1 3.5 4 0 0 4 4 2 0 Domain of unknown function (DUF4162) IBR PF01485.21 KFP02313.1 - 5.4 7.3 13.2 25 5.2 13.1 2.2 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Dynamin_M PF01031.20 KFP02314.1 - 2.8e-104 348.3 0.1 9.2e-104 346.6 0.0 1.9 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.23 KFP02314.1 - 1.8e-50 171.3 0.5 4.4e-50 170.0 0.1 1.8 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 KFP02314.1 - 1.8e-31 108.2 2.7 1.8e-31 108.2 2.7 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain LRR_8 PF13855.6 KFP02315.1 - 3.9e-37 125.8 29.1 4.2e-14 52.1 12.2 3.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFP02315.1 - 1.8e-17 63.2 17.3 8.7e-06 26.0 0.1 4.6 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) I-set PF07679.16 KFP02315.1 - 1.6e-15 56.9 0.0 3.4e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_5 PF13306.6 KFP02315.1 - 3e-15 56.3 0.1 1e-14 54.6 0.1 1.9 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) Ig_3 PF13927.6 KFP02315.1 - 3e-13 50.2 0.0 7.1e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP02315.1 - 7.7e-10 38.8 0.0 1.5e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.33 KFP02315.1 - 1.1e-09 37.5 8.5 0.95 10.3 0.0 6.7 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_9 PF14580.6 KFP02315.1 - 6.4e-09 35.5 5.7 5.6e-05 22.7 3.7 2.5 1 1 1 2 2 2 2 Leucine-rich repeat Ig_2 PF13895.6 KFP02315.1 - 8.4e-07 29.2 0.0 2.2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.21 KFP02315.1 - 0.00022 21.5 0.0 0.00063 20.0 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain C2-set_2 PF08205.12 KFP02315.1 - 0.0073 16.3 0.0 0.02 14.9 0.0 1.8 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain LSR PF05624.14 KFP02315.1 - 0.013 15.4 1.5 0.013 15.4 1.5 2.4 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) V-set PF07686.17 KFP02315.1 - 0.037 14.2 0.0 8.6 6.6 0.0 2.4 1 1 1 2 2 2 0 Immunoglobulin V-set domain DUF240 PF03086.14 KFP02315.1 - 0.12 12.3 4.6 0.2 11.6 3.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF240) PDEase_I PF00233.19 KFP02316.1 - 9.2e-28 97.6 2.8 9.7e-28 97.5 2.8 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Neuro_bHLH PF12533.8 KFP02317.1 - 1.3e-19 71.6 1.1 2.3e-19 70.8 0.3 1.8 2 0 0 2 2 2 1 Neuronal helix-loop-helix transcription factor HLH PF00010.26 KFP02317.1 - 7e-16 57.9 2.5 9e-16 57.6 0.8 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain CCDC106 PF15794.5 KFP02317.1 - 0.0025 17.6 1.1 0.0033 17.2 1.1 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 106 Nop53 PF07767.11 KFP02317.1 - 0.018 14.5 8.9 0.022 14.2 8.9 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) eIF3_subunit PF08597.10 KFP02317.1 - 0.033 14.1 6.8 0.047 13.6 6.8 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CDC45 PF02724.14 KFP02317.1 - 0.048 11.9 3.7 0.055 11.8 3.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_60s PF00428.19 KFP02317.1 - 3.4 8.3 9.5 18 6.0 9.6 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein XendoU PF09412.10 KFP02318.1 - 4e-94 314.8 0.0 4.5e-94 314.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU Somatomedin_B PF01033.17 KFP02318.1 - 7e-08 32.7 14.9 1.1e-07 32.1 14.9 1.3 1 0 0 1 1 1 1 Somatomedin B domain EndoU_bacteria PF14436.6 KFP02318.1 - 0.0012 19.2 0.1 0.0022 18.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial EndoU nuclease PDZ PF00595.24 KFP02321.1 - 2e-20 72.9 0.2 2.2e-15 56.7 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFP02321.1 - 1.2e-15 57.1 1.5 3.4e-13 49.2 0.3 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFP02321.1 - 3e-07 30.7 0.1 1.1e-06 28.9 0.0 1.9 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 KFP02321.1 - 0.02 14.9 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain Glyco_transf_8 PF01501.20 KFP02322.1 - 7.8e-08 32.2 1.1 1.4e-07 31.3 1.1 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KFP02322.1 - 0.019 14.4 0.3 0.032 13.7 0.3 1.4 1 1 0 1 1 1 0 Glucosyltransferase 24 YAF2_RYBP PF17219.3 KFP02323.1 - 1.1e-19 69.7 0.2 1.8e-19 69.0 0.2 1.4 1 0 0 1 1 1 1 Yaf2/RYBP C-terminal binding motif U3_snoRNA_assoc PF08297.11 KFP02323.1 - 0.52 11.1 11.5 1.1 10.0 11.5 1.6 1 1 0 1 1 1 0 U3 snoRNA associated CPSF100_C PF13299.6 KFP02323.1 - 8.5 6.5 9.5 1.7 8.8 5.5 1.7 1 1 1 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RRM_1 PF00076.22 KFP02324.1 - 3.1e-22 78.2 0.2 5e-22 77.5 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP02324.1 - 7.3e-09 35.3 0.0 1.2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KFP02324.1 - 3.2e-05 23.8 2.0 5.6e-05 23.0 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle SET_assoc PF11767.8 KFP02324.1 - 0.01 15.5 0.0 0.026 14.2 0.0 1.7 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated zf-CCHC_3 PF13917.6 KFP02324.1 - 0.013 15.5 0.8 0.024 14.6 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle BRAP2 PF07576.12 KFP02324.1 - 0.015 15.5 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 BRCA1-associated protein 2 RRM_7 PF16367.5 KFP02324.1 - 0.019 15.0 0.0 0.051 13.7 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif RRM_occluded PF16842.5 KFP02324.1 - 0.025 14.4 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KFP02324.1 - 0.037 14.1 0.3 0.16 12.0 0.3 2.0 1 1 0 1 1 1 0 Limkain b1 PET PF06297.14 KFP02325.1 - 5.5e-39 132.4 1.1 1.5e-38 130.9 1.1 1.8 1 0 0 1 1 1 1 PET Domain LIM PF00412.22 KFP02325.1 - 3.5e-25 88.0 40.3 2e-09 37.5 3.3 3.7 3 0 0 3 3 3 3 LIM domain Vasculin PF15337.6 KFP02325.1 - 0.0028 18.5 1.0 0.015 16.2 0.0 2.6 2 0 0 2 2 2 1 Vascular protein family Vasculin-like 1 Pkinase PF00069.25 KFP02326.1 - 1.1e-52 179.0 0.0 1.5e-52 178.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP02326.1 - 1e-48 165.9 0.0 1.8e-48 165.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP02326.1 - 0.00013 20.9 0.0 0.00022 20.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Death PF00531.22 KFP02326.1 - 0.005 17.0 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 Death domain Cofilin_ADF PF00241.20 KFP02327.1 - 1.6e-40 137.7 0.1 2.5e-20 72.5 0.0 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein TusA PF01206.17 KFP02327.1 - 0.15 11.9 0.0 0.46 10.3 0.0 1.8 1 0 0 1 1 1 0 Sulfurtransferase TusA TMEM117 PF15113.6 KFP02328.1 - 5.1e-228 756.9 28.0 5.9e-228 756.7 28.0 1.0 1 0 0 1 1 1 1 TMEM117 protein family 7tm_1 PF00001.21 KFP02329.1 - 9e-30 103.9 23.5 1.3e-29 103.3 23.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PHO4 PF01384.20 KFP02329.1 - 3.8 6.5 7.9 5 6.1 7.8 1.5 1 1 0 1 1 1 0 Phosphate transporter family EGF_CA PF07645.15 KFP02330.1 - 1.7e-29 101.7 63.9 7.5e-12 45.3 6.6 11.0 9 2 1 10 10 8 5 Calcium-binding EGF domain VWC PF00093.18 KFP02330.1 - 2.2e-18 66.3 63.6 2.8e-10 40.4 14.4 10.3 6 1 3 9 9 6 4 von Willebrand factor type C domain EGF_3 PF12947.7 KFP02330.1 - 2.6e-13 49.9 38.2 1.3e-08 34.9 14.1 10.6 10 2 1 11 11 9 5 EGF domain cEGF PF12662.7 KFP02330.1 - 3.3e-10 39.7 12.2 6e-08 32.5 3.1 10.8 11 0 0 11 11 11 5 Complement Clr-like EGF-like Laminin_G_2 PF02210.24 KFP02330.1 - 2.1e-07 31.6 0.1 3.8e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 Laminin G domain EGF PF00008.27 KFP02330.1 - 6.9e-06 26.2 21.0 6.2e-05 23.2 8.4 11.7 12 1 1 13 13 8 5 EGF-like domain hEGF PF12661.7 KFP02330.1 - 5.5e-05 23.6 30.6 0.0018 18.9 5.9 12.3 12 0 0 12 12 9 5 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 KFP02330.1 - 0.00015 21.7 8.8 0.00015 21.7 8.8 8.9 9 0 0 9 9 9 3 MSP1 EGF domain 1 TILa PF12714.7 KFP02330.1 - 0.00016 21.5 24.5 0.00074 19.4 7.4 11.5 8 5 3 11 11 8 4 TILa domain Laminin_G_3 PF13385.6 KFP02330.1 - 0.00018 21.7 0.0 0.00032 20.9 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_1 PF00054.23 KFP02330.1 - 0.00028 21.1 0.0 0.00075 19.7 0.0 1.7 1 1 0 1 1 1 1 Laminin G domain FXa_inhibition PF14670.6 KFP02330.1 - 0.013 15.8 6.5 0.013 15.8 6.5 10.8 8 2 3 11 11 8 0 Coagulation Factor Xa inhibitory site Hormone_1 PF00103.20 KFP02331.1 - 3.2e-29 102.2 1.1 3.8e-29 102.0 1.1 1.1 1 0 0 1 1 1 1 Somatotropin hormone family Homeodomain PF00046.29 KFP02332.1 - 4.8e-21 74.4 4.9 1.1e-20 73.3 4.9 1.6 1 0 0 1 1 1 1 Homeodomain DUF2986 PF11661.8 KFP02332.1 - 0.0043 17.5 1.9 0.0077 16.7 0.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2986) Homeobox_KN PF05920.11 KFP02332.1 - 0.032 14.1 2.0 0.034 14.0 0.2 2.0 3 0 0 3 3 3 0 Homeobox KN domain ARID PF01388.21 KFP02333.1 - 2.4e-25 89.0 0.2 9.5e-25 87.1 0.0 2.2 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain RFX_DNA_binding PF02257.15 KFP02333.1 - 1.9e-23 82.8 0.1 3.8e-23 81.9 0.1 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain BAF250_C PF12031.8 KFP02333.1 - 0.62 9.3 6.9 1.1 8.5 0.7 3.0 1 1 1 2 2 2 0 SWI/SNF-like complex subunit BAF250/Osa Aa_trans PF01490.18 KFP02335.1 - 7.2e-76 255.5 40.3 9e-76 255.2 40.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Cation_ATPase_C PF00689.21 KFP02335.1 - 5.7e-05 22.9 11.3 5.7e-05 22.9 11.3 3.2 1 1 2 3 3 3 1 Cation transporting ATPase, C-terminus Aa_trans PF01490.18 KFP02336.1 - 3.8e-79 266.3 42.6 4.5e-79 266.1 42.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 KFP02337.1 - 3.7e-82 276.2 34.5 7.1e-46 156.7 13.3 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein LRR_8 PF13855.6 KFP02338.1 - 3.8e-23 81.0 7.9 1.4e-12 47.2 4.4 4.3 2 1 2 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 KFP02338.1 - 8e-12 45.2 15.4 1.7e-05 25.1 2.4 4.7 1 1 6 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP02338.1 - 4.7e-07 29.4 14.1 0.063 13.9 0.2 7.3 7 1 0 7 7 7 2 Leucine Rich Repeat LRR_5 PF13306.6 KFP02338.1 - 9.3e-07 28.9 0.2 2e-06 27.8 0.2 1.5 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP02338.1 - 1.2e-06 28.2 0.3 2.8e-06 26.9 0.2 1.6 1 1 0 1 1 1 1 Leucine-rich repeat Ig_3 PF13927.6 KFP02338.1 - 2.2e-06 28.2 0.0 5.8e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP02338.1 - 7e-06 26.1 0.0 1.7e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP02338.1 - 0.00018 21.5 0.0 0.00036 20.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 KFP02338.1 - 0.00022 21.3 0.0 0.00056 20.0 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin V-set domain LRRNT PF01462.18 KFP02338.1 - 0.0037 16.9 1.7 0.0037 16.9 1.7 3.6 5 0 0 5 5 5 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 KFP02338.1 - 0.0053 16.7 11.4 1.3 9.3 0.1 5.7 6 0 0 6 6 6 1 Leucine Rich repeat UPF0220 PF05255.11 KFP02338.1 - 0.025 14.1 0.0 4 6.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0220) Ig_2 PF13895.6 KFP02338.1 - 0.027 14.8 0.0 0.064 13.6 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Herpes_gE PF02480.16 KFP02338.1 - 0.051 12.3 0.0 3.7 6.2 0.0 2.1 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E TPR_1 PF00515.28 KFP02339.1 - 1.6e-36 122.6 23.3 4.6e-06 26.2 1.1 7.0 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 KFP02339.1 - 1.3e-28 96.8 22.6 9.9e-05 22.2 0.1 6.7 6 0 0 6 6 6 6 Tetratricopeptide repeat RPAP3_C PF13877.6 KFP02339.1 - 1.1e-25 89.9 0.6 3.8e-25 88.2 0.6 2.0 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_8 PF13181.6 KFP02339.1 - 3.5e-20 70.5 17.0 0.0022 18.1 0.4 7.3 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 KFP02339.1 - 2.5e-18 65.5 17.6 6.3e-05 22.6 0.3 6.2 3 2 3 6 6 6 4 TPR repeat TPR_7 PF13176.6 KFP02339.1 - 4.2e-16 57.7 5.9 0.00011 22.0 0.0 5.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFP02339.1 - 3.9e-13 49.0 1.5 0.0062 17.3 0.1 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFP02339.1 - 8.2e-13 48.8 4.9 0.0021 18.6 2.3 4.3 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFP02339.1 - 5.2e-11 42.7 14.3 0.04 14.2 2.8 5.5 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 KFP02339.1 - 2.4e-10 40.4 0.4 0.0023 18.1 0.2 4.5 3 2 2 5 5 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFP02339.1 - 3.3e-09 37.1 10.4 0.017 15.6 0.6 4.6 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFP02339.1 - 0.00011 22.5 10.0 9.7 7.1 0.6 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFP02339.1 - 0.00013 22.1 19.4 0.22 12.0 0.3 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFP02339.1 - 0.0021 17.9 10.5 5.5 7.0 0.5 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP02339.1 - 0.0034 17.6 4.2 0.07 13.4 0.1 3.6 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 KFP02339.1 - 0.0047 17.0 18.1 0.12 12.4 0.1 6.1 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 KFP02339.1 - 0.0067 16.5 11.2 0.71 10.0 0.1 4.9 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain PPR PF01535.20 KFP02339.1 - 0.011 15.9 0.9 10 6.6 0.0 4.0 3 0 0 3 3 3 0 PPR repeat FAT PF02259.23 KFP02339.1 - 0.096 11.9 9.1 0.41 9.8 0.3 2.7 1 1 1 2 2 2 0 FAT domain Reprolysin_5 PF13688.6 KFP02339.1 - 0.13 12.4 0.1 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 Metallo-peptidase family M12 RPN7 PF10602.9 KFP02339.1 - 0.16 11.7 0.0 0.16 11.7 0.0 4.3 4 1 1 5 5 5 0 26S proteasome subunit RPN7 MutS_IV PF05190.18 KFP02339.1 - 2.6 8.4 7.1 2.5 8.5 2.1 3.3 3 0 0 3 3 3 0 MutS family domain IV Alkyl_sulf_dimr PF14863.6 KFP02339.1 - 6.2 7.3 6.4 84 3.6 0.4 3.5 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation Peptidase_M76 PF09768.9 KFP02340.1 - 3.5e-55 186.4 6.8 4.1e-55 186.2 6.8 1.0 1 0 0 1 1 1 1 Peptidase M76 family HypD PF01924.16 KFP02340.1 - 0.014 14.5 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase formation hypA family Peptidase_M90 PF06167.12 KFP02340.1 - 0.033 13.8 0.2 0.046 13.3 0.2 1.2 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 SprT-like PF10263.9 KFP02340.1 - 0.046 13.6 1.2 0.084 12.7 1.2 1.4 1 0 0 1 1 1 0 SprT-like family LRR_8 PF13855.6 KFP02341.1 - 5.3e-94 308.0 101.2 1.1e-15 57.1 2.2 7.8 2 1 8 10 10 10 10 Leucine rich repeat I-set PF07679.16 KFP02341.1 - 2.8e-49 165.1 0.0 1.8e-19 69.6 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP02341.1 - 2.9e-44 149.5 0.0 5.9e-14 52.4 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain LRR_4 PF12799.7 KFP02341.1 - 1.5e-36 123.8 52.5 3.6e-06 27.2 0.8 9.6 3 2 8 12 12 12 11 Leucine Rich repeats (2 copies) Ig_2 PF13895.6 KFP02341.1 - 3.1e-28 97.9 0.0 1.1e-07 32.1 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain LRR_5 PF13306.6 KFP02341.1 - 3.6e-28 98.1 0.8 7.2e-11 42.1 0.0 4.0 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) ig PF00047.25 KFP02341.1 - 2e-26 92.0 0.0 4.8e-07 29.9 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain LRR_9 PF14580.6 KFP02341.1 - 5.7e-19 68.3 19.8 1.3e-05 24.8 1.0 5.4 1 1 4 5 5 5 5 Leucine-rich repeat V-set PF07686.17 KFP02341.1 - 1.5e-12 47.7 3.0 0.018 15.2 0.2 5.7 3 3 1 4 4 4 3 Immunoglobulin V-set domain LRR_1 PF00560.33 KFP02341.1 - 1.3e-10 40.3 34.9 0.31 11.7 1.0 13.6 14 1 0 14 14 14 2 Leucine Rich Repeat Ig_6 PF18452.1 KFP02341.1 - 3.2e-09 36.2 0.0 0.029 13.9 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 KFP02341.1 - 7.2e-09 35.6 0.0 0.0028 17.7 0.0 3.7 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFP02341.1 - 4.2e-07 30.3 0.0 0.3 11.5 0.0 4.5 3 1 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFP02341.1 - 3.9e-05 23.6 1.1 2.5 8.2 0.0 4.2 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain C1-set PF07654.15 KFP02341.1 - 0.00075 19.8 0.1 0.019 15.3 0.0 3.0 3 0 0 3 3 3 1 Immunoglobulin C1-set domain C2-set PF05790.15 KFP02341.1 - 0.033 14.4 0.3 7.7 6.8 0.0 3.9 5 0 0 5 5 5 0 Immunoglobulin C2-set domain Receptor_2B4 PF11465.8 KFP02341.1 - 0.067 13.4 0.0 2.3 8.5 0.0 2.7 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 LRR_6 PF13516.6 KFP02341.1 - 5.3 7.3 58.1 1.9 8.7 1.0 13.0 15 0 0 15 15 13 0 Leucine Rich repeat MFS_1 PF07690.16 KFP02342.1 - 8e-41 140.1 32.3 1.7e-35 122.6 27.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFP02342.1 - 0.00038 19.4 12.4 0.029 13.2 0.1 3.4 2 1 0 3 3 3 3 MFS_1 like family Sugar_tr PF00083.24 KFP02342.1 - 0.0023 16.8 9.2 0.0023 16.8 9.2 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter DUF2140 PF09911.9 KFP02342.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Pardaxin PF07425.11 KFP02342.1 - 1.6 8.4 4.9 0.28 10.8 0.6 2.1 2 0 0 2 2 2 0 Pardaxin dUTPase PF00692.19 KFP02343.1 - 9e-13 48.0 0.0 1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 dUTPase RVT_1 PF00078.27 KFP02345.1 - 1.1e-16 61.0 0.0 2.6e-16 59.8 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) 7tm_4 PF13853.6 KFP02346.1 - 5e-13 49.4 0.2 5.2e-13 49.4 0.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP02346.1 - 6.7e-13 48.6 0.5 6.8e-13 48.5 0.5 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP02346.1 - 0.0032 16.9 0.1 0.0033 16.9 0.1 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Gsf2 PF11055.8 KFP02346.1 - 0.15 10.8 0.0 0.15 10.8 0.0 1.0 1 0 0 1 1 1 0 Glucose signalling factor 2 Ank_2 PF12796.7 KFP02347.1 - 0.0084 16.7 0.0 0.029 14.9 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) MFS_1 PF07690.16 KFP02348.1 - 1.2e-37 129.7 29.6 1.9e-25 89.5 18.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP02348.1 - 2.7e-33 115.5 21.2 4.4e-30 104.9 6.6 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter Pentapeptide_4 PF13599.6 KFP02348.1 - 2e-08 34.3 5.4 3.5e-08 33.5 5.4 1.4 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) MFS_4 PF06779.14 KFP02348.1 - 0.0004 19.8 9.3 0.0004 19.8 9.3 2.3 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB Pentapeptide_3 PF13576.6 KFP02348.1 - 0.0027 17.8 4.2 0.096 12.9 3.1 2.9 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) MFS_3 PF05977.13 KFP02348.1 - 0.019 13.4 6.5 0.48 8.8 0.3 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Pentapeptide PF00805.22 KFP02348.1 - 0.053 13.2 0.1 1.7 8.4 0.0 2.6 1 1 2 3 3 3 0 Pentapeptide repeats (8 copies) OATP PF03137.20 KFP02349.1 - 3.6e-176 586.7 7.8 4.3e-176 586.4 7.8 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFP02349.1 - 1.2e-26 93.5 8.4 1.2e-26 93.5 8.4 2.9 2 2 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.15 KFP02349.1 - 7.7e-07 29.1 14.0 1.3e-06 28.4 10.3 2.5 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFP02349.1 - 0.0081 16.2 8.6 0.038 14.0 8.6 2.1 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain PUCC PF03209.15 KFP02349.1 - 0.2 10.6 13.6 0.27 10.2 0.1 3.8 4 0 0 4 4 4 0 PUCC protein Glyco_transf_29 PF00777.18 KFP02350.1 - 8.4e-74 248.4 0.0 9.4e-74 248.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) DUF1180 PF06679.12 KFP02351.1 - 5.7e-19 69.1 1.1 6e-19 69.1 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) SNF2_N PF00176.23 KFP02352.1 - 5.9e-67 225.8 0.6 1.1e-66 224.9 0.6 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain CDH1_2_SANT_HL1 PF18375.1 KFP02352.1 - 6.6e-34 116.5 0.0 6.6e-34 116.5 0.0 5.5 5 1 0 5 5 5 1 CDH1/2 SANT-Helical linker 1 Chromo PF00385.24 KFP02352.1 - 1.3e-31 108.3 10.5 1.6e-20 72.7 0.0 3.8 3 1 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 KFP02352.1 - 4.2e-25 88.0 0.9 4.2e-25 88.0 0.9 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 KFP02352.1 - 9.6e-20 71.0 0.0 2.7e-19 69.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP02352.1 - 1.5e-08 34.8 0.0 1.5e-08 34.8 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CHDCT2 PF08074.11 KFP02352.1 - 0.00065 19.9 0.0 0.033 14.4 0.0 3.2 2 0 0 2 2 2 1 CHDCT2 (NUC038) domain Myb_DNA-binding PF00249.31 KFP02352.1 - 0.0028 17.8 0.1 0.053 13.7 0.1 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain SLIDE PF09111.10 KFP02352.1 - 0.005 16.8 0.1 0.005 16.8 0.1 3.4 3 1 0 3 3 3 1 SLIDE RGM_C PF06534.13 KFP02353.1 - 3.9e-73 244.6 0.0 5.3e-73 244.2 0.0 1.2 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) C-terminus RGM_N PF06535.12 KFP02353.1 - 4.5e-72 241.6 1.2 6.8e-72 241.0 1.2 1.3 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) N-terminus C8 PF08742.11 KFP02353.1 - 1.4 9.4 5.6 2.5 8.6 0.0 3.0 3 0 0 3 3 3 0 C8 domain DUF4578 PF15147.6 KFP02354.1 - 0.25 12.2 5.4 0.26 12.2 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4578) PBC PF03792.13 KFP02355.1 - 4.2e-67 225.6 0.5 6.2e-67 225.0 0.1 1.5 2 0 0 2 2 2 1 PBC domain Homeodomain PF00046.29 KFP02355.1 - 8.6e-20 70.3 0.9 2e-19 69.1 0.9 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP02355.1 - 4.5e-16 58.5 0.0 1.1e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 KFP02355.1 - 0.0021 17.9 0.0 0.0051 16.6 0.0 1.6 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 KFP02355.1 - 0.0089 16.1 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix Sec15 PF04091.12 KFP02355.1 - 0.01 15.3 0.6 0.015 14.7 0.6 1.3 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like LZ3wCH PF18517.1 KFP02355.1 - 0.15 12.2 0.0 1 9.5 0.0 2.3 2 0 0 2 2 2 0 Leucine zipper with capping helix domain NUC130_3NT PF08158.12 KFP02355.1 - 0.45 10.9 1.6 26 5.2 0.1 3.0 3 1 0 3 3 3 0 NUC130/3NT domain LIM PF00412.22 KFP02356.1 - 2e-31 108.0 22.8 3.1e-16 59.3 6.7 2.3 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 KFP02356.1 - 4.9e-18 64.7 2.5 8.4e-18 64.0 2.5 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP02356.1 - 0.00011 22.0 0.0 0.00026 20.8 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain DUF4636 PF15468.6 KFP02356.1 - 0.36 10.5 3.2 0.52 10.0 2.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4636) Hormone_recep PF00104.30 KFP02357.1 - 3.1e-38 131.4 0.0 6.1e-38 130.5 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Nuc_recep-AF1 PF11825.8 KFP02357.1 - 2.4e-33 114.6 14.6 4.3e-33 113.7 14.6 1.4 1 0 0 1 1 1 1 Nuclear/hormone receptor activator site AF-1 zf-C4 PF00105.18 KFP02357.1 - 4.5e-32 110.3 15.8 7.8e-32 109.6 15.8 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Sushi PF00084.20 KFP02358.1 - 1e-51 173.4 61.4 1.1e-09 38.7 2.8 7.2 7 0 0 7 7 7 6 Sushi repeat (SCR repeat) Lectin_C PF00059.21 KFP02358.1 - 1.4e-21 77.3 4.7 1.4e-21 77.3 4.7 2.7 4 0 0 4 4 4 1 Lectin C-type domain EGF_2 PF07974.13 KFP02358.1 - 6.4e-05 23.2 10.2 6.4e-05 23.2 10.2 3.9 4 0 0 4 4 4 1 EGF-like domain EGF PF00008.27 KFP02358.1 - 0.0014 18.9 11.6 0.0014 18.9 11.6 4.1 6 0 0 6 6 6 1 EGF-like domain hEGF PF12661.7 KFP02358.1 - 0.015 15.9 6.6 0.015 15.9 6.6 5.4 4 0 0 4 4 4 0 Human growth factor-like EGF Antistasin PF02822.14 KFP02358.1 - 0.93 10.2 26.7 22 5.8 0.1 8.4 8 0 0 8 8 8 0 Antistasin family Ocnus PF05005.15 KFP02359.1 - 7.3e-41 138.6 0.4 8.1e-41 138.5 0.4 1.0 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) Methyltransf_16 PF10294.9 KFP02360.1 - 3.7e-13 49.6 0.1 2.2e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 KFP02360.1 - 4.8e-07 29.8 0.0 7.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP02360.1 - 4.7e-06 26.5 0.1 0.014 15.2 0.1 2.2 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 KFP02360.1 - 3.1e-05 23.6 0.0 5.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KFP02360.1 - 0.00012 22.7 0.0 0.49 11.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain PrmA PF06325.13 KFP02360.1 - 0.00029 20.3 0.0 0.00047 19.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 KFP02360.1 - 0.015 15.0 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 KFP02360.1 - 0.023 15.4 0.0 0.082 13.6 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase domain AbiJ_NTD5 PF18865.1 KFP02360.1 - 0.061 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 Pkinase PF00069.25 KFP02361.1 - 0.00039 19.9 0.0 0.0031 16.9 0.0 2.2 1 1 1 2 2 2 1 Protein kinase domain KAP PF05804.12 KFP02362.1 - 0 1241.0 24.1 0 1240.9 24.1 1.0 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Arm PF00514.23 KFP02362.1 - 0.0043 17.1 13.5 0.67 10.1 0.1 6.6 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat FPL PF09758.9 KFP02362.1 - 0.13 12.2 7.5 0.065 13.2 2.9 2.8 3 0 0 3 3 3 0 Uncharacterised conserved protein Methyltransf_PK PF05891.12 KFP02363.1 - 4e-69 232.5 0.0 7.6e-69 231.6 0.0 1.4 2 0 0 2 2 2 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KFP02363.1 - 2.7e-06 28.0 0.0 4.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP02363.1 - 0.00035 21.2 0.0 0.00056 20.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP02363.1 - 0.0015 19.2 0.0 0.0024 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KFP02363.1 - 0.0089 15.3 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Transcrip_act PF04949.13 KFP02364.1 - 3.8e-07 30.1 18.7 6.8e-07 29.3 18.7 1.4 1 1 0 1 1 1 1 Transcriptional activator DUF1828 PF08861.10 KFP02364.1 - 8.1 6.8 6.8 1.4 9.2 1.3 2.4 2 1 0 2 2 2 0 Domain of unknown function DUF1828 Homeodomain PF00046.29 KFP02365.1 - 3.4e-23 81.2 6.4 6.3e-23 80.4 6.4 1.5 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 KFP02365.1 - 4.7e-08 32.6 0.1 9.1e-08 31.7 0.1 1.5 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 KFP02365.1 - 0.00049 19.9 0.2 0.0014 18.4 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain FMO-like PF00743.19 KFP02366.1 - 2.5e-234 778.6 0.0 2.8e-234 778.5 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFP02366.1 - 1e-16 61.1 0.0 2.7e-13 49.9 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFP02366.1 - 1e-12 47.9 0.0 4.3e-11 42.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFP02366.1 - 7.4e-10 38.5 0.0 4.7e-08 32.6 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KFP02366.1 - 0.00018 21.7 0.0 0.00043 20.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFP02366.1 - 0.00031 20.4 0.0 0.13 11.8 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KFP02366.1 - 0.00034 20.6 0.0 0.0023 17.9 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KFP02366.1 - 0.0031 18.0 0.3 2.8 8.5 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase OLF PF02191.16 KFP02367.1 - 1e-82 277.5 0.0 1.1e-82 277.3 0.0 1.0 1 0 0 1 1 1 1 Olfactomedin-like domain Glyco_hydro_1 PF00232.18 KFP02368.1 - 1e-162 541.7 3.6 1.2e-162 541.5 3.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_10 PF00331.20 KFP02368.1 - 0.016 14.4 0.4 0.55 9.3 0.0 2.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 10 Zwilch PF09817.9 KFP02369.1 - 7.9e-168 559.5 1.8 1.3e-167 558.8 1.8 1.3 1 1 0 1 1 1 1 RZZ complex, subunit zwilch PPR PF01535.20 KFP02369.1 - 0.035 14.4 0.1 23 5.5 0.0 3.4 2 0 0 2 2 2 0 PPR repeat WD40 PF00400.32 KFP02370.1 - 9.1e-20 70.6 11.2 1.8e-06 28.5 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KFP02370.1 - 0.00085 18.2 0.4 1 8.0 0.1 2.8 2 2 1 3 3 3 2 Nup133 N terminal like ANAPC4_WD40 PF12894.7 KFP02370.1 - 0.0017 18.6 0.1 5.9 7.3 0.0 3.8 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFP02370.1 - 0.066 12.5 0.0 2.2 7.5 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain CX9C PF16860.5 KFP02371.1 - 0.0011 18.9 2.7 0.36 10.9 0.2 2.1 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 KFP02371.1 - 0.002 18.2 8.6 0.0029 17.7 8.6 1.3 1 0 0 1 1 1 1 CHCH domain DB PF01682.19 KFP02371.1 - 0.0085 16.4 1.0 0.0093 16.2 1.0 1.1 1 0 0 1 1 1 1 DB module Cmc1 PF08583.10 KFP02371.1 - 0.021 14.9 4.7 0.42 10.7 1.0 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 KFP02371.1 - 0.052 13.9 3.1 0.074 13.4 3.1 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) DUF3128 PF11326.8 KFP02371.1 - 0.12 12.8 3.1 4.5 7.7 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) Ribosomal_S10 PF00338.22 KFP02372.1 - 4.1e-16 59.0 0.4 6.6e-16 58.3 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e CarD_CdnL_TRCF PF02559.16 KFP02372.1 - 0.075 13.8 0.2 0.2 12.4 0.2 1.9 1 1 0 1 1 1 0 CarD-like/TRCF domain Ras PF00071.22 KFP02373.1 - 1.3e-53 180.9 0.8 1.6e-53 180.7 0.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP02373.1 - 1.8e-32 112.0 0.2 2.8e-32 111.5 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP02373.1 - 4e-12 45.9 0.4 4.4e-12 45.8 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP02373.1 - 3.1e-05 23.6 0.4 6.3e-05 22.6 0.2 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFP02373.1 - 0.00016 21.2 0.1 0.00019 20.9 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFP02373.1 - 0.0012 18.9 0.1 0.0021 18.1 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase PH PF00169.29 KFP02375.1 - 8.4e-09 35.9 0.0 1.1e-08 35.6 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFP02375.1 - 0.00075 19.9 0.4 0.0014 19.0 0.4 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KFP02375.1 - 0.0028 17.9 0.2 0.037 14.3 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_15 PF17339.2 KFP02375.1 - 0.13 12.1 0.0 0.25 11.3 0.0 1.4 1 1 0 1 1 1 0 PH domain TCRP1 PF14944.6 KFP02377.1 - 6.2e-104 347.3 47.7 7e-104 347.1 47.7 1.0 1 0 0 1 1 1 1 Tongue Cancer Chemotherapy Resistant Protein 1 RhoGEF PF00621.20 KFP02378.1 - 8.6e-44 149.9 3.1 1.5e-43 149.2 3.1 1.4 1 0 0 1 1 1 1 RhoGEF domain BBS2_Mid PF14783.6 KFP02378.1 - 0.0011 18.9 0.0 0.0028 17.7 0.0 1.6 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, middle region PIN_5 PF08745.11 KFP02378.1 - 0.1 12.0 0.5 0.21 11.0 0.5 1.4 1 0 0 1 1 1 0 PINc domain ribonuclease Amidohydro_1 PF01979.20 KFP02379.1 - 9.4e-20 71.2 0.0 1.2e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFP02379.1 - 1.5e-07 31.3 0.0 2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Pkinase PF00069.25 KFP02380.1 - 3.8e-16 59.2 0.0 6.1e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP02380.1 - 0.0064 15.8 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase FancD2 PF14631.6 KFP02380.1 - 0.093 10.1 0.1 0.1 10.0 0.1 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Yae1_N PF09811.9 KFP02381.1 - 1.8e-10 40.3 29.8 17 5.2 29.8 3.2 1 1 0 1 1 1 1 Essential protein Yae1, N terminal Paralemmin PF03285.15 KFP02382.1 - 3.1e-92 309.5 23.5 4.5e-91 305.7 23.5 2.0 1 1 0 1 1 1 1 Paralemmin AKAP2_C PF15304.6 KFP02383.1 - 2.6e-15 56.6 18.7 2.6e-15 56.6 18.7 2.8 2 1 0 2 2 2 1 A-kinase anchor protein 2 C-terminus Misat_Tub_SegII PF10644.9 KFP02383.1 - 0.059 13.7 0.1 0.059 13.7 0.1 3.1 3 1 0 3 3 3 0 Misato Segment II tubulin-like domain PX PF00787.24 KFP02384.1 - 6.7e-24 84.0 1.8 1.3e-23 83.1 1.8 1.4 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KFP02384.1 - 3.5e-08 33.3 1.7 0.0015 18.2 0.0 2.5 2 1 1 3 3 3 2 Vps5 C terminal like BAR PF03114.18 KFP02384.1 - 5.7e-07 29.4 0.3 5.7e-07 29.4 0.3 1.6 2 0 0 2 2 2 1 BAR domain BAR_3_WASP_bdg PF10456.9 KFP02384.1 - 0.0074 15.8 0.2 0.018 14.5 0.0 1.6 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein SOSSC PF15925.5 KFP02385.1 - 6.7e-23 81.9 0.8 4.7e-22 79.2 0.8 1.9 1 1 0 1 1 1 1 SOSS complex subunit C DUF3504 PF12012.8 KFP02386.1 - 4.6e-20 72.2 0.0 1.5e-19 70.5 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3504) Phage_int_SAM_5 PF13102.6 KFP02386.1 - 0.0022 18.3 0.3 0.0059 16.9 0.3 1.7 1 0 0 1 1 1 1 Phage integrase SAM-like domain Phage_int_SAM_4 PF13495.6 KFP02386.1 - 0.1 13.1 0.2 0.35 11.4 0.1 1.9 1 1 1 2 2 2 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.17 KFP02386.1 - 0.12 12.7 0.5 19 5.6 0.1 2.6 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain adh_short PF00106.25 KFP02387.1 - 1.7e-33 115.7 0.2 3.1e-33 114.9 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP02387.1 - 4.4e-27 95.2 0.5 7.1e-27 94.5 0.5 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SCP2 PF02036.17 KFP02387.1 - 4.3e-23 81.7 0.1 8.7e-23 80.7 0.1 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family KR PF08659.10 KFP02387.1 - 0.00066 19.6 0.9 0.0009 19.2 0.2 1.5 2 0 0 2 2 2 1 KR domain Alkyl_sulf_C PF14864.6 KFP02387.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal RRM_5 PF13893.6 KFP02388.1 - 7.3e-52 174.2 1.7 5.1e-38 129.5 0.0 4.1 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KFP02388.1 - 2.2e-32 110.7 0.6 2.7e-09 36.7 0.0 5.1 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KFP02388.1 - 6.6e-13 48.7 0.0 5.2e-12 45.8 0.0 2.3 2 0 0 2 2 2 1 RRM-like domain RRM_occluded PF16842.5 KFP02388.1 - 1.5e-10 40.8 0.2 0.032 14.1 0.0 4.4 4 0 0 4 4 4 4 Occluded RNA-recognition motif EGF_CA PF07645.15 KFP02389.1 - 1.2e-15 57.4 24.4 2.3e-09 37.3 8.0 4.4 5 0 0 5 5 5 2 Calcium-binding EGF domain EGF_3 PF12947.7 KFP02389.1 - 1.1e-13 51.1 33.9 2e-06 27.9 4.9 4.4 3 1 1 4 4 4 3 EGF domain Sushi PF00084.20 KFP02389.1 - 3.2e-13 50.1 26.8 8.9e-08 32.6 0.6 5.4 5 0 0 5 5 5 2 Sushi repeat (SCR repeat) cEGF PF12662.7 KFP02389.1 - 6.9e-12 45.1 26.7 1.3e-07 31.5 2.4 4.8 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 KFP02389.1 - 4.3e-06 26.7 29.4 0.00079 19.4 7.8 3.9 3 0 0 3 3 3 3 MSP1 EGF domain 1 FXa_inhibition PF14670.6 KFP02389.1 - 2.9e-05 24.3 32.6 0.0032 17.7 6.2 4.3 3 1 1 4 4 4 2 Coagulation Factor Xa inhibitory site hEGF PF12661.7 KFP02389.1 - 0.00034 21.1 32.8 0.22 12.2 7.8 4.9 3 0 0 3 3 3 3 Human growth factor-like EGF EGF PF00008.27 KFP02389.1 - 0.0014 18.8 7.6 0.0014 18.8 7.6 5.0 5 0 0 5 5 5 1 EGF-like domain fn3 PF00041.21 KFP02389.1 - 0.0054 17.1 0.0 19 5.7 0.0 3.4 3 0 0 3 3 3 1 Fibronectin type III domain Glyco_transf_21 PF13506.6 KFP02391.1 - 1e-58 197.6 0.0 1.4e-58 197.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KFP02391.1 - 1.1e-23 84.4 0.0 1.3e-23 84.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KFP02391.1 - 3.6e-12 46.6 3.8 4.7e-12 46.2 3.8 1.1 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KFP02391.1 - 0.00041 20.2 0.0 0.00089 19.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 Chitin_synth_2 PF03142.15 KFP02391.1 - 0.043 12.4 0.0 0.071 11.7 0.0 1.3 1 0 0 1 1 1 0 Chitin synthase G-gamma PF00631.22 KFP02392.1 - 1e-09 38.2 0.0 1.1e-09 38.2 0.0 1.0 1 0 0 1 1 1 1 GGL domain L31 PF09784.9 KFP02393.1 - 0.046 14.1 2.2 0.13 12.7 2.2 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 Ecm29 PF13001.7 KFP02394.1 - 3.9e-146 487.6 0.4 3.9e-146 487.6 0.4 3.9 5 0 0 5 5 5 1 Proteasome stabiliser HEAT_2 PF13646.6 KFP02394.1 - 3.5e-13 49.8 3.3 0.96 9.9 0.0 8.7 7 1 1 8 8 8 4 HEAT repeats Vac14_Fab1_bd PF12755.7 KFP02394.1 - 3.2e-12 46.9 0.0 0.00096 19.7 0.1 8.3 9 1 1 10 10 10 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KFP02394.1 - 1.4e-11 43.6 14.2 1.5 9.3 0.0 12.9 14 0 0 14 14 14 3 HEAT repeat HEAT_EZ PF13513.6 KFP02394.1 - 9.7e-11 41.9 10.5 3.3 8.3 0.1 11.0 12 0 0 12 12 12 2 HEAT-like repeat IFRD PF05004.13 KFP02394.1 - 1.1e-05 24.7 18.9 0.022 13.9 0.0 6.5 6 0 0 6 6 6 2 Interferon-related developmental regulator (IFRD) Adaptin_N PF01602.20 KFP02394.1 - 0.00036 19.2 13.8 0.063 11.8 0.4 6.1 5 2 0 6 6 6 3 Adaptin N terminal region CLASP_N PF12348.8 KFP02394.1 - 0.18 11.3 14.4 0.11 12.1 0.2 5.5 6 1 1 7 7 7 0 CLASP N terminal Catalase-rel PF06628.12 KFP02394.1 - 0.2 11.9 0.1 9 6.6 0.0 3.3 3 0 0 3 3 3 0 Catalase-related immune-responsive RTP1_C1 PF10363.9 KFP02394.1 - 1.2 9.3 8.5 15 5.8 0.1 5.4 7 0 0 7 7 7 0 Required for nuclear transport of RNA pol II C-terminus 1 ADH_N_2 PF16884.5 KFP02395.1 - 4.5e-36 123.0 0.0 8.7e-36 122.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KFP02395.1 - 3e-22 79.0 0.0 4.5e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFP02395.1 - 5.3e-10 40.5 0.0 9.8e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Prot_ATP_ID_OB PF16450.5 KFP02395.1 - 0.14 12.1 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain Thioredoxin PF00085.20 KFP02396.1 - 2e-30 104.8 0.9 2.1e-30 104.7 0.9 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KFP02396.1 - 7.8e-06 26.1 0.3 1.2e-05 25.5 0.3 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KFP02396.1 - 4.5e-05 23.9 0.2 0.00012 22.5 0.2 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFP02396.1 - 0.00019 21.5 0.1 0.0003 20.9 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 KFP02396.1 - 0.00032 20.9 0.3 0.00056 20.1 0.3 1.4 1 0 0 1 1 1 1 Glutaredoxin AhpC-TSA PF00578.21 KFP02396.1 - 0.00074 19.4 0.2 0.001 19.0 0.2 1.3 1 1 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 KFP02396.1 - 0.00076 18.9 0.3 0.00085 18.8 0.3 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DIM1 PF02966.16 KFP02396.1 - 0.0045 16.8 0.1 0.0048 16.7 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Redoxin PF08534.10 KFP02396.1 - 0.0092 15.7 0.2 0.012 15.3 0.2 1.3 1 1 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.6 KFP02396.1 - 0.014 15.2 0.1 0.021 14.6 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin Pkinase_Tyr PF07714.17 KFP02397.1 - 2.4e-94 315.4 0.0 3.3e-94 315.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase I-set PF07679.16 KFP02397.1 - 3.4e-46 155.2 0.0 5.4e-20 71.3 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP02397.1 - 2e-41 140.5 0.4 2.9e-16 59.8 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Pkinase PF00069.25 KFP02397.1 - 6.2e-40 137.2 0.0 1.4e-39 136.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Ig_2 PF13895.6 KFP02397.1 - 2.3e-27 95.1 2.4 8.2e-11 42.1 0.0 3.8 4 0 0 4 4 3 3 Immunoglobulin domain Kringle PF00051.18 KFP02397.1 - 2.5e-23 82.2 6.5 6.1e-23 80.9 6.5 1.7 1 0 0 1 1 1 1 Kringle domain ig PF00047.25 KFP02397.1 - 3.6e-17 62.3 0.0 3.2e-08 33.6 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain Fz PF01392.22 KFP02397.1 - 1.2e-15 58.1 4.4 2.7e-15 56.9 4.4 1.7 1 0 0 1 1 1 1 Fz domain C2-set_2 PF08205.12 KFP02397.1 - 2.5e-10 40.3 0.2 0.0055 16.8 0.0 3.7 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFP02397.1 - 6e-09 36.1 3.6 0.0061 16.7 0.0 5.1 4 2 0 4 4 4 2 Immunoglobulin V-set domain Ig_6 PF18452.1 KFP02397.1 - 6e-06 25.7 0.0 0.17 11.5 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain Herpes_gE PF02480.16 KFP02397.1 - 0.00061 18.6 1.9 0.43 9.3 0.0 3.6 3 1 1 4 4 4 2 Alphaherpesvirus glycoprotein E Ig_4 PF16680.5 KFP02397.1 - 0.00063 20.0 0.0 0.85 9.9 0.0 3.9 4 1 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Adeno_E3_CR1 PF02440.15 KFP02397.1 - 0.0037 17.0 0.0 1.5 8.6 0.0 2.9 3 0 0 3 3 3 1 Adenovirus E3 region protein CR1 Haspin_kinase PF12330.8 KFP02397.1 - 0.022 13.7 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Izumo-Ig PF16706.5 KFP02397.1 - 0.042 13.9 0.1 0.74 9.9 0.0 2.4 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain CD34_antigen PF06365.12 KFP02397.1 - 0.068 12.7 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family TMEM100 PF16311.5 KFP02397.1 - 0.14 11.8 0.1 0.27 10.8 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 100 Sterol-sensing PF12349.8 KFP02397.1 - 1.8 8.4 3.8 10 5.9 0.0 2.3 2 0 0 2 2 2 0 Sterol-sensing domain of SREBP cleavage-activation 7tm_1 PF00001.21 KFP02398.1 - 2.3e-39 135.3 23.3 3.1e-39 134.9 23.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP02398.1 - 1.7e-05 24.7 17.0 0.00032 20.5 17.0 2.1 1 1 0 1 1 1 1 Olfactory receptor PRODH PF18327.1 KFP02399.1 - 0.07 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Proline utilization A proline dehydrogenase N-terminal domain RVT_1 PF00078.27 KFP02399.1 - 0.074 12.6 0.0 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Guanylate_cyc PF00211.20 KFP02400.1 - 3.6e-62 209.2 0.2 3e-61 206.2 0.0 2.1 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 KFP02400.1 - 8.3e-42 143.3 0.0 1.3e-41 142.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP02400.1 - 6.2e-34 117.6 0.0 1.1e-33 116.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 KFP02400.1 - 1.5e-06 27.8 1.5 2.4e-06 27.2 1.5 1.3 1 0 0 1 1 1 1 Heme NO binding associated TMEM215 PF15746.5 KFP02401.1 - 3.4e-117 389.7 0.9 3.8e-117 389.6 0.9 1.0 1 0 0 1 1 1 1 TMEM215 family zf-C3HC4_2 PF13923.6 KFP02402.1 - 1.1e-10 41.2 7.9 1.1e-10 41.2 7.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP02402.1 - 1e-09 38.1 5.5 1e-09 38.1 5.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP02402.1 - 3e-09 36.6 7.1 3e-09 36.6 7.1 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP02402.1 - 7.8e-09 35.7 9.0 7.8e-09 35.7 9.0 2.1 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFP02402.1 - 1.6e-07 31.2 3.6 2.4e-07 30.7 1.8 2.4 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFP02402.1 - 7e-06 26.1 7.7 2.6e-05 24.3 7.7 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KFP02402.1 - 9.9e-06 25.8 5.5 4.3e-05 23.7 5.5 2.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFP02402.1 - 1.6e-05 24.7 8.2 1.6e-05 24.7 8.2 2.2 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP02402.1 - 0.00086 19.1 10.0 0.017 15.0 9.6 2.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFP02402.1 - 0.0041 17.1 3.1 0.01 15.9 3.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KFP02402.1 - 0.083 12.7 9.2 0.32 10.8 9.2 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain TLV_coat PF00429.19 KFP02403.1 - 0.012 14.3 0.2 0.014 14.1 0.2 1.0 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) Yae1_N PF09811.9 KFP02404.1 - 7.7e-18 63.9 63.5 1.8e+04 -28.3 63.5 6.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal RVT_1 PF00078.27 KFP02406.1 - 0.069 12.6 0.0 5.6 6.4 0.0 2.7 3 0 0 3 3 3 0 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.22 KFP02407.1 - 1.9e-67 223.0 0.1 2e-21 75.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP02407.1 - 3.7e-12 45.9 0.0 0.00013 21.6 0.0 3.1 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KFP02407.1 - 0.00015 22.0 0.0 0.72 10.1 0.0 2.8 3 0 0 3 3 3 2 BRCA1-associated protein 2 RRM_occluded PF16842.5 KFP02407.1 - 0.00031 20.5 0.0 0.97 9.3 0.0 3.4 3 1 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 KFP02407.1 - 0.00052 20.1 0.0 1.1 9.5 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif RRM_3 PF08777.11 KFP02407.1 - 0.00055 19.9 0.0 0.5 10.5 0.0 2.5 2 0 0 2 2 2 2 RNA binding motif RRM_2 PF04059.12 KFP02407.1 - 0.039 14.2 0.1 0.29 11.4 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif 2 RNA_bind PF08675.11 KFP02407.1 - 0.11 12.6 0.0 2.8 8.0 0.0 2.7 2 1 0 2 2 2 0 RNA binding domain Yae1_N PF09811.9 KFP02409.1 - 1.2e-12 47.2 37.5 10 5.9 0.2 4.4 2 1 0 2 2 2 2 Essential protein Yae1, N terminal CAAP1 PF15335.6 KFP02410.1 - 3.6e-29 101.1 9.5 6.1e-29 100.4 9.5 1.4 1 0 0 1 1 1 1 Caspase activity and apoptosis inhibitor 1 PUL PF08324.11 KFP02411.1 - 7.2e-64 215.7 4.8 1e-63 215.2 4.8 1.1 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 KFP02411.1 - 3.4e-40 136.8 0.2 6e-40 136.0 0.2 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 KFP02411.1 - 6.8e-35 118.5 9.7 7.5e-06 26.6 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat WD40_like PF17005.5 KFP02411.1 - 0.00038 19.9 0.0 0.45 9.8 0.0 2.5 1 1 1 2 2 2 2 WD40-like domain BBS2_Mid PF14783.6 KFP02411.1 - 0.0031 17.5 0.0 2.6 8.1 0.0 3.0 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Spc7 PF08317.11 KFP02412.1 - 1.2 7.9 80.0 0.009 14.9 6.4 5.2 1 1 3 4 4 4 0 Spc7 kinetochore protein PilJ PF13675.6 KFP02412.1 - 2.3 8.3 13.3 0.19 11.8 0.5 4.3 2 2 2 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term Occludin_ELL PF07303.13 KFP02412.1 - 4.4 8.1 61.1 0.39 11.5 7.3 6.4 3 2 3 6 6 6 0 Occludin homology domain FUSC PF04632.12 KFP02412.1 - 5.1 5.5 13.4 0.16 10.5 1.0 2.2 1 1 1 3 3 3 0 Fusaric acid resistance protein family LRR19-TM PF15176.6 KFP02413.1 - 6.5e-26 90.3 0.0 1.1e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain LRR_8 PF13855.6 KFP02413.1 - 6.2e-18 64.3 18.1 5.9e-15 54.8 6.7 3.3 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KFP02413.1 - 1.6e-06 28.3 25.8 0.0026 18.1 4.9 3.8 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP02413.1 - 7.9e-05 22.6 8.1 7.9e-05 22.6 8.1 2.7 3 1 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFP02413.1 - 0.00018 21.6 15.8 2.4 9.0 0.0 6.2 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_9 PF14580.6 KFP02413.1 - 0.0017 17.8 2.5 0.0017 17.8 2.5 2.0 1 1 1 2 2 2 1 Leucine-rich repeat Pkinase_Tyr PF07714.17 KFP02414.1 - 4.9e-92 307.9 0.0 7.1e-92 307.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP02414.1 - 3e-44 151.4 0.0 4.9e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ig_Tie2_1 PF10430.9 KFP02414.1 - 1e-39 134.8 0.1 2.6e-39 133.5 0.1 1.7 1 0 0 1 1 1 1 Tie-2 Ig-like domain 1 fn3 PF00041.21 KFP02414.1 - 4.9e-30 103.7 4.9 2e-11 44.0 0.7 3.4 3 0 0 3 3 3 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFP02414.1 - 2.6e-12 47.2 1.7 0.0024 18.4 0.2 4.3 4 0 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain Ig_3 PF13927.6 KFP02414.1 - 1.3e-06 28.9 0.2 0.027 15.0 0.0 5.1 5 0 0 5 5 5 1 Immunoglobulin domain I-set PF07679.16 KFP02414.1 - 3.8e-06 26.9 0.0 0.00028 20.9 0.0 3.4 3 0 0 3 3 3 1 Immunoglobulin I-set domain fn3_2 PF16893.5 KFP02414.1 - 7e-06 26.1 0.1 0.019 15.1 0.1 3.8 4 0 0 4 4 3 1 Fibronectin type III domain EGF_2 PF07974.13 KFP02414.1 - 0.00017 21.9 12.0 0.00017 21.9 12.0 5.1 5 0 0 5 5 5 2 EGF-like domain ig PF00047.25 KFP02414.1 - 0.00048 20.3 0.0 0.015 15.4 0.0 3.2 3 0 0 3 3 3 1 Immunoglobulin domain hEGF PF12661.7 KFP02414.1 - 0.0007 20.1 6.6 0.0007 20.1 6.6 4.7 4 0 0 4 4 3 2 Human growth factor-like EGF APH PF01636.23 KFP02414.1 - 0.0016 18.4 0.0 0.14 12.1 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Interfer-bind PF09294.10 KFP02414.1 - 0.0056 17.0 0.4 25 5.3 0.0 3.5 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III V-set PF07686.17 KFP02414.1 - 0.0057 16.8 0.0 1 9.5 0.0 3.2 3 0 0 3 3 2 1 Immunoglobulin V-set domain EGF PF00008.27 KFP02414.1 - 0.014 15.7 11.9 0.014 15.7 11.9 4.6 4 0 0 4 4 4 0 EGF-like domain Laminin_EGF PF00053.24 KFP02414.1 - 0.024 14.8 48.5 3.8 7.7 11.8 4.1 2 1 1 3 3 3 0 Laminin EGF domain Haspin_kinase PF12330.8 KFP02414.1 - 0.046 12.7 0.0 0.083 11.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Glyco_hydro_36C PF16874.5 KFP02414.1 - 0.048 14.1 0.0 1.1 9.9 0.0 2.9 3 0 0 3 3 2 0 Glycosyl hydrolase family 36 C-terminal domain Izumo-Ig PF16706.5 KFP02414.1 - 0.092 12.8 0.0 0.86 9.7 0.0 2.7 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain DUF4702 PF15774.5 KFP02414.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4702) Pkinase_fungal PF17667.1 KFP02414.1 - 0.15 10.8 0.0 0.29 9.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Mob1_phocein PF03637.17 KFP02415.1 - 1.1e-80 269.6 0.2 1.2e-80 269.4 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family C9orf72-like PF15019.6 KFP02416.1 - 2.2e-97 325.4 0.0 3.2e-97 324.9 0.0 1.2 1 0 0 1 1 1 1 C9orf72-like protein family LRR_8 PF13855.6 KFP02417.1 - 1.1e-57 191.7 57.5 6.4e-13 48.3 1.0 6.3 2 2 5 7 7 7 7 Leucine rich repeat LRR_5 PF13306.6 KFP02417.1 - 8.2e-26 90.5 0.0 1.2e-09 38.2 0.0 3.2 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFP02417.1 - 7.3e-20 70.7 31.7 0.00012 22.4 1.0 7.5 3 2 5 9 9 9 7 Leucine Rich repeats (2 copies) I-set PF07679.16 KFP02417.1 - 7.9e-17 61.1 0.0 1.3e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP02417.1 - 1.6e-14 54.3 0.0 3.6e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP02417.1 - 7.5e-09 35.7 0.0 1.7e-08 34.5 0.0 1.6 2 0 0 2 2 1 1 Immunoglobulin domain LRR_1 PF00560.33 KFP02417.1 - 5.7e-07 29.2 28.6 47 5.1 0.1 12.1 12 1 0 12 12 12 0 Leucine Rich Repeat Ig_2 PF13895.6 KFP02417.1 - 1.4e-06 28.5 0.7 2.3e-06 27.9 0.0 1.7 2 0 0 2 2 1 1 Immunoglobulin domain LRRNT PF01462.18 KFP02417.1 - 2.8e-05 23.7 2.6 2.8e-05 23.7 2.6 3.3 4 0 0 4 4 4 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 KFP02417.1 - 0.00039 20.0 14.5 0.054 13.0 4.5 3.3 2 1 1 3 3 3 3 Leucine-rich repeat V-set PF07686.17 KFP02417.1 - 0.00082 19.5 0.1 0.017 15.3 0.1 2.7 2 1 0 2 2 2 1 Immunoglobulin V-set domain Ig_C17orf99 PF17736.1 KFP02417.1 - 0.02 14.9 0.0 0.068 13.2 0.0 1.9 2 0 0 2 2 2 0 C17orf99 Ig domain Ig_6 PF18452.1 KFP02417.1 - 0.062 12.9 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain HTH_Tnp_IS630 PF01710.16 KFP02417.1 - 0.064 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Transposase TLV_coat PF00429.19 KFP02419.1 - 0.0048 15.6 0.1 0.005 15.6 0.1 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) AKNA PF12443.8 KFP02419.1 - 0.022 15.4 0.1 0.026 15.2 0.1 1.1 1 0 0 1 1 1 0 AT-hook-containing transcription factor Tetraspanin PF00335.20 KFP02420.1 - 5.2e-22 78.7 8.0 6.8e-22 78.3 8.0 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF4635 PF15466.6 KFP02420.1 - 0.031 13.8 0.4 0.072 12.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) CD225 PF04505.12 KFP02420.1 - 0.67 10.1 7.2 2.5 8.3 0.0 3.4 2 1 1 3 3 3 0 Interferon-induced transmembrane protein DUF1899 PF08953.11 KFP02421.1 - 1.1e-29 102.1 0.2 1.8e-29 101.4 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KFP02421.1 - 2.4e-20 72.1 0.0 4e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KFP02421.1 - 4e-18 65.5 5.7 2.7e-06 28.0 0.3 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP02421.1 - 4e-09 36.7 0.0 4.2e-05 23.8 0.0 3.2 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Sacchrp_dh_NADP PF03435.18 KFP02421.1 - 0.031 14.5 0.0 0.082 13.2 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ge1_WD40 PF16529.5 KFP02421.1 - 0.16 10.9 0.1 2.9 6.7 0.0 2.4 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RabGAP-TBC PF00566.18 KFP02422.1 - 7.3e-53 179.4 1.2 7.3e-53 179.4 1.2 2.7 2 1 0 3 3 3 1 Rab-GTPase-TBC domain PH PF00169.29 KFP02422.1 - 1.8e-10 41.3 0.1 5.8e-10 39.6 0.1 1.9 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFP02422.1 - 0.00015 22.0 0.2 0.00043 20.5 0.1 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 KFP02422.1 - 0.0007 20.0 0.5 0.0051 17.2 0.5 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain MHC_II_beta PF00969.19 KFP02422.1 - 0.14 12.3 0.5 1.4 9.1 0.2 2.8 3 0 0 3 3 3 0 Class II histocompatibility antigen, beta domain Mce4_CUP1 PF11887.8 KFP02422.1 - 3.9 6.8 6.2 0.55 9.7 1.7 1.7 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative PKcGMP_CC PF16808.5 KFP02422.1 - 4 7.4 11.1 0.86 9.5 3.1 3.3 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DnaJ_C PF01556.18 KFP02423.1 - 4.3e-44 150.2 0.3 5.7e-44 149.8 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KFP02423.1 - 4.2e-15 55.9 20.7 7.9e-15 55.0 20.7 1.5 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.31 KFP02423.1 - 5.3e-06 26.5 0.2 1e-05 25.5 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain Anti-TRAP PF15777.5 KFP02423.1 - 0.029 14.3 11.8 0.43 10.6 4.5 2.6 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KFP02423.1 - 0.061 13.3 8.1 0.72 9.9 0.9 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA UL97 PF06734.12 KFP02423.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 UL97 WD40 PF00400.32 KFP02424.1 - 1.2e-40 136.8 8.9 7.6e-08 32.9 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP02424.1 - 5.5e-18 65.1 0.1 1.2e-05 25.5 0.0 5.5 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP02424.1 - 9.4e-14 51.1 0.5 0.0025 16.8 0.1 3.6 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH_TPL PF17814.1 KFP02424.1 - 1.2e-13 50.4 0.2 2.3e-13 49.5 0.2 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain Nup160 PF11715.8 KFP02424.1 - 3.9e-09 35.7 0.3 0.0011 17.8 0.1 3.9 2 1 2 4 4 4 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KFP02424.1 - 0.0022 17.9 1.5 1.5 8.7 0.2 3.6 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Hira PF07569.11 KFP02424.1 - 0.0033 17.2 1.7 1.6 8.4 0.0 4.4 5 0 0 5 5 5 1 TUP1-like enhancer of split PD40 PF07676.12 KFP02424.1 - 0.018 14.9 0.0 0.7 9.9 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat LisH PF08513.11 KFP02424.1 - 0.022 14.7 0.0 0.051 13.6 0.0 1.7 1 0 0 1 1 1 0 LisH Glyco_transf_7N PF13733.6 KFP02425.1 - 1.8e-58 196.0 0.1 2.4e-58 195.5 0.1 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 KFP02425.1 - 3.5e-32 109.9 0.2 6.3e-32 109.1 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KFP02425.1 - 0.043 13.3 0.1 0.21 11.0 0.1 1.9 1 1 1 2 2 2 0 Glycosyltransferase like family 2 Kazal_1 PF00050.21 KFP02426.1 - 3e-16 59.2 5.3 5e-16 58.5 1.8 2.0 1 1 1 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KFP02426.1 - 6.5e-12 45.4 2.8 1.3e-11 44.4 1.1 1.9 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Peptidase_C62 PF12380.8 KFP02426.1 - 0.08 12.1 0.1 0.085 12.0 0.1 1.1 1 0 0 1 1 1 0 Gill-associated viral 3C-like peptidase zf-RING_11 PF17123.5 KFP02426.1 - 0.5 10.2 4.1 0.24 11.2 0.7 2.0 2 0 0 2 2 2 0 RING-like zinc finger XPA_C PF05181.12 KFP02429.1 - 2.4e-29 101.0 1.2 2.8e-29 100.8 1.2 1.0 1 0 0 1 1 1 1 XPA protein C-terminus MIF4G_like_2 PF09090.11 KFP02430.1 - 8.7e-86 287.7 3.2 8.7e-86 287.7 3.2 1.5 2 0 0 2 2 2 1 MIF4G like MIF4G_like PF09088.11 KFP02430.1 - 8.1e-37 126.9 0.9 5.4e-36 124.2 0.6 2.3 2 0 0 2 2 2 1 MIF4G like MIF4G PF02854.19 KFP02430.1 - 4.4e-26 91.8 2.2 6.7e-26 91.2 0.1 2.5 3 0 0 3 3 3 1 MIF4G domain DUF4611 PF15387.6 KFP02430.1 - 0.033 14.4 1.0 0.033 14.4 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Nuf2 PF03800.14 KFP02430.1 - 0.066 13.3 0.0 4.2 7.5 0.0 2.7 1 1 1 2 2 2 0 Nuf2 family Vfa1 PF08432.10 KFP02430.1 - 0.071 13.4 1.2 0.14 12.5 1.2 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mis12 PF05859.12 KFP02430.1 - 0.087 12.9 1.9 0.36 10.9 1.4 2.3 2 0 0 2 2 2 0 Mis12 protein ApoA-II PF04711.13 KFP02430.1 - 0.12 12.6 0.6 0.61 10.3 0.0 2.5 3 0 0 3 3 3 0 Apolipoprotein A-II (ApoA-II) DASH_Spc34 PF08657.10 KFP02430.1 - 0.39 10.5 5.7 0.74 9.6 5.7 1.4 1 0 0 1 1 1 0 DASH complex subunit Spc34 PBP1_TM PF14812.6 KFP02430.1 - 0.92 9.9 10.9 0.11 12.9 5.6 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UPF0176_N PF17773.1 KFP02431.1 - 4.5e-17 62.2 0.0 7.8e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 KFP02431.1 - 5.9e-15 55.4 14.2 2.3e-14 53.5 14.2 2.1 1 0 0 1 1 1 1 Rhodanase C-terminal Rhodanese PF00581.20 KFP02431.1 - 3.1e-07 30.9 0.0 7e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Tropomodulin PF03250.14 KFP02432.1 - 7.9e-41 139.4 9.9 8.8e-41 139.3 7.0 2.4 2 1 0 2 2 2 1 Tropomodulin LRR_6 PF13516.6 KFP02432.1 - 0.012 15.7 0.2 0.06 13.4 0.1 2.4 2 0 0 2 2 2 0 Leucine Rich repeat DUF3644 PF12358.8 KFP02432.1 - 0.073 13.6 0.2 0.25 11.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3644) DAGK_acc PF00609.19 KFP02433.1 - 4e-50 170.3 0.0 8.1e-50 169.3 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KFP02433.1 - 7.5e-23 80.5 0.0 1.5e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain RA PF00788.23 KFP02433.1 - 6.6e-17 61.9 2.0 5.1e-10 39.9 0.4 3.3 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain C1_1 PF00130.22 KFP02433.1 - 1.1e-14 54.0 40.9 9e-12 44.7 6.1 4.0 3 1 1 4 4 4 3 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KFP02433.1 - 0.0057 16.9 4.1 0.0057 16.9 4.1 3.9 3 1 1 4 4 4 2 C1 domain Aconitase PF00330.20 KFP02434.1 - 5.3e-180 599.3 0.0 7e-180 598.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KFP02434.1 - 1.5e-45 154.7 0.0 2.9e-44 150.5 0.0 2.3 2 0 0 2 2 2 1 Aconitase C-terminal domain RIG-I_C PF18119.1 KFP02435.1 - 5.1e-36 123.8 1.7 5.1e-36 123.8 1.7 2.5 2 0 0 2 2 2 1 RIG-I receptor C-terminal domain RIG-I_C-RD PF11648.8 KFP02435.1 - 8.8e-32 109.8 4.0 8.8e-32 109.8 4.0 2.4 3 0 0 3 3 3 1 C-terminal domain of RIG-I CARD_2 PF16739.5 KFP02435.1 - 1.1e-20 73.4 2.3 1.1e-20 73.3 0.3 2.2 2 0 0 2 2 2 1 Caspase recruitment domain DEAD PF00270.29 KFP02435.1 - 6e-20 71.7 0.1 2.2e-19 69.9 0.1 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KFP02435.1 - 2.5e-18 66.7 1.2 6.8e-17 62.0 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFP02435.1 - 1.1e-13 51.4 0.0 4.5e-13 49.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 KFP02435.1 - 0.0077 16.6 0.1 0.21 11.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFP02435.1 - 0.017 15.4 0.2 0.11 12.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KFP02435.1 - 0.025 14.1 0.0 0.07 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 KFP02435.1 - 0.15 11.5 3.9 2.1 7.8 0.0 2.7 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain PNP_UDP_1 PF01048.20 KFP02436.1 - 2.9e-47 160.9 0.0 3.2e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily NLPC_P60 PF00877.19 KFP02436.1 - 0.03 14.3 0.0 0.057 13.4 0.0 1.6 1 0 0 1 1 1 0 NlpC/P60 family Carboxyl_trans PF01039.22 KFP02437.1 - 5.5e-144 480.5 0.0 2.9e-71 240.6 0.0 2.0 2 0 0 2 2 2 2 Carboxyl transferase domain MdcE PF06833.11 KFP02437.1 - 0.00046 19.7 0.1 0.42 10.1 0.0 2.3 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) Myb_DNA-bind_7 PF15963.5 KFP02438.1 - 3.8e-28 97.2 3.7 3.8e-28 97.2 3.7 3.3 4 1 1 5 5 5 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KFP02438.1 - 0.00026 21.1 0.0 0.00058 20.0 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ctr PF04145.15 KFP02438.1 - 0.19 12.3 0.1 3.4 8.3 0.0 2.3 1 1 1 2 2 2 0 Ctr copper transporter family RNA_pol_3_Rpc31 PF11705.8 KFP02438.1 - 0.33 11.2 25.6 0.39 10.9 9.0 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CNDH2_C PF16858.5 KFP02438.1 - 1.8 8.4 21.7 1.3 8.9 2.7 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Zip PF02535.22 KFP02438.1 - 7.7 5.6 10.2 8.1 5.6 4.0 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Pox_Ag35 PF03286.14 KFP02438.1 - 9.4 6.0 25.8 1.3 8.7 3.8 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein 4F5 PF04419.14 KFP02439.1 - 2.4e-08 34.7 10.6 2.4e-08 34.7 10.6 2.1 2 0 0 2 2 2 1 4F5 protein family Ssl1 PF04056.14 KFP02440.1 - 1e-92 309.2 0.1 1.4e-92 308.8 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 KFP02440.1 - 3.6e-13 50.1 0.0 9.5e-13 48.7 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain C1_4 PF07975.12 KFP02440.1 - 2.9e-11 43.4 25.8 3.2e-10 40.1 19.0 2.9 2 1 0 2 2 2 2 TFIIH C1-like domain VWA PF00092.28 KFP02440.1 - 8.4e-07 29.4 0.0 1.2e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFP02440.1 - 0.027 14.4 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain Matrix PF00661.21 KFP02440.1 - 0.1 11.3 0.2 0.14 10.9 0.2 1.2 1 0 0 1 1 1 0 Viral matrix protein IBR PF01485.21 KFP02440.1 - 1.3 9.3 20.1 0.76 10.0 12.3 2.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Occludin_ELL PF07303.13 KFP02441.1 - 1.4e-29 102.8 11.2 2.4e-29 102.0 11.2 1.4 1 0 0 1 1 1 1 Occludin homology domain MARVEL PF01284.23 KFP02441.1 - 1.4e-14 54.4 7.2 1.8e-14 54.0 7.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain Sec34 PF04136.15 KFP02441.1 - 0.039 13.8 1.9 0.042 13.7 0.3 1.7 2 0 0 2 2 2 0 Sec34-like family Tex_N PF09371.10 KFP02441.1 - 0.056 13.1 2.7 0.091 12.4 2.7 1.3 1 0 0 1 1 1 0 Tex-like protein N-terminal domain DUF1241 PF06840.11 KFP02441.1 - 0.06 13.0 0.3 0.11 12.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) DUF202 PF02656.15 KFP02441.1 - 2.3 8.7 6.0 15 6.1 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) EMP24_GP25L PF01105.24 KFP02442.1 - 1.1e-33 116.7 0.0 1.3e-33 116.5 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CDO_I PF05995.12 KFP02443.1 - 4e-53 179.2 0.1 4.6e-53 179.0 0.1 1.0 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KFP02443.1 - 0.00011 21.7 0.3 0.00045 19.7 0.3 1.8 1 1 0 1 1 1 1 PCO_ADO Clat_adaptor_s PF01217.20 KFP02444.1 - 1.4e-41 141.7 2.9 1.7e-41 141.5 2.9 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ARF7EP_C PF14949.6 KFP02445.1 - 1.4e-35 122.1 14.6 1.6e-35 121.9 14.6 1.0 1 0 0 1 1 1 1 ARF7 effector protein C-terminus COMM_domain PF07258.14 KFP02446.1 - 2.9e-06 27.3 0.1 2.9e-06 27.3 0.1 2.4 3 0 0 3 3 3 1 COMM domain Sema PF01403.19 KFP02447.1 - 1e-134 449.6 0.1 1.5e-134 449.0 0.1 1.2 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 KFP02447.1 - 5e-07 30.2 3.0 1.3e-06 28.8 3.0 1.7 1 0 0 1 1 1 1 Plexin repeat DUF3481 PF11980.8 KFP02447.1 - 0.084 12.6 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein DTW PF03942.15 KFP02449.1 - 2.9e-40 138.1 0.2 3.5e-40 137.8 0.2 1.1 1 0 0 1 1 1 1 DTW domain Rav1p_C PF12234.8 KFP02450.1 - 9.4e-89 298.5 0.8 1.6e-76 258.1 0.1 2.3 1 1 0 2 2 2 2 RAVE protein 1 C terminal WD40 PF00400.32 KFP02450.1 - 8.1e-13 48.6 30.7 0.019 15.8 0.0 12.2 14 0 0 14 14 14 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP02450.1 - 0.00053 20.2 0.0 16 5.9 0.0 4.8 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF758 PF05527.11 KFP02451.1 - 3.7e-77 258.4 8.9 4.1e-77 258.3 8.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) Pico_P2B PF01552.17 KFP02451.1 - 0.0024 18.0 0.8 0.0054 16.9 0.4 1.8 2 1 0 2 2 2 1 Picornavirus 2B protein DUF2408 PF10303.9 KFP02451.1 - 0.029 14.9 3.7 0.081 13.5 3.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) HD_3 PF13023.6 KFP02451.1 - 0.034 14.1 0.9 0.075 13.0 1.0 1.5 2 0 0 2 2 2 0 HD domain DUF459 PF04311.13 KFP02451.1 - 0.038 13.0 0.3 0.051 12.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF459) DUF4771 PF15995.5 KFP02451.1 - 0.038 14.2 1.0 0.048 13.9 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4771) Nup54 PF13874.6 KFP02451.1 - 0.049 13.7 3.2 0.043 13.9 1.7 1.7 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 MaoC_dehydratas PF01575.19 KFP02452.1 - 4.5e-38 129.6 0.0 8.2e-38 128.7 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain adh_short PF00106.25 KFP02452.1 - 7.7e-34 116.9 0.0 1.8e-33 115.6 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP02452.1 - 1.4e-32 113.1 0.0 3.5e-32 111.9 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SCP2 PF02036.17 KFP02452.1 - 2.6e-26 92.1 0.4 5.7e-26 91.0 0.4 1.6 1 0 0 1 1 1 1 SCP-2 sterol transfer family KR PF08659.10 KFP02452.1 - 4.5e-11 43.0 0.0 8.6e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 KR domain MaoC_dehydrat_N PF13452.6 KFP02452.1 - 1.1e-08 35.2 0.0 4.7e-07 30.0 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Alkyl_sulf_C PF14864.6 KFP02452.1 - 1.2e-07 32.0 0.1 2.6e-07 30.9 0.1 1.5 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal ApoC-I PF04691.12 KFP02452.1 - 0.067 13.1 0.1 0.59 10.1 0.0 2.3 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) Collagen PF01391.18 KFP02455.1 - 3e-32 110.2 118.7 1e-10 41.2 21.0 4.1 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) C4 PF01413.19 KFP02456.1 - 1.4e-83 276.5 1.2 3.6e-45 152.9 0.1 2.0 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Integrase_H2C2 PF17921.1 KFP02456.1 - 0.08 13.1 1.4 8.4 6.6 0.1 2.4 2 0 0 2 2 2 0 Integrase zinc binding domain Ras PF00071.22 KFP02457.1 - 6.5e-32 110.4 0.0 2.1e-31 108.7 0.0 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFP02457.1 - 1.8e-23 83.1 0.0 2.8e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP02457.1 - 7.1e-14 51.6 0.0 8.8e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP02457.1 - 3.9e-05 23.7 0.0 8e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP02457.1 - 0.00025 20.7 0.0 0.0024 17.5 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFP02457.1 - 0.04 13.8 0.1 11 5.8 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 KFP02457.1 - 0.058 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KFP02457.1 - 0.083 13.3 0.0 0.12 12.8 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1_Xtn PF16897.5 KFP02457.1 - 0.098 12.7 0.0 4.3 7.4 0.0 2.2 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain Carb_kinase PF01256.17 KFP02458.1 - 1.4e-55 188.5 0.0 1.7e-55 188.2 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 KFP02458.1 - 0.043 13.2 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family Suc_Fer-like PF06999.12 KFP02458.1 - 0.051 13.4 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 Sucrase/ferredoxin-like tRNA-synt_1e PF01406.19 KFP02459.1 - 1e-98 330.5 0.5 1.3e-98 330.1 0.5 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KFP02459.1 - 5.7e-08 31.9 1.2 0.00025 19.9 0.2 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KFP02459.1 - 0.00038 18.9 0.0 0.00048 18.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.11 KFP02459.1 - 0.0023 18.4 0.0 0.0057 17.1 0.0 1.7 1 0 0 1 1 1 1 DALR domain tRNA-synt_1f PF01921.18 KFP02459.1 - 0.046 12.6 0.5 0.087 11.7 0.1 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (K) ING PF12998.7 KFP02460.1 - 3e-30 104.8 5.2 3e-30 104.8 5.2 2.0 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KFP02460.1 - 1.9e-06 27.7 8.4 4.6e-06 26.4 8.4 1.7 1 0 0 1 1 1 1 PHD-finger SRP-alpha_N PF04086.13 KFP02460.1 - 0.0011 19.0 13.4 0.0016 18.4 13.4 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal PHD_2 PF13831.6 KFP02460.1 - 0.013 15.1 3.1 0.024 14.2 3.1 1.4 1 0 0 1 1 1 0 PHD-finger DUF4661 PF15576.6 KFP02460.1 - 0.014 15.3 4.1 0.021 14.7 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) ZYG-11_interact PF05884.12 KFP02460.1 - 0.06 12.7 0.5 0.088 12.2 0.5 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 SF3A3 PF16837.5 KFP02460.1 - 0.09 13.3 0.3 0.2 12.2 0.3 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 NPR3 PF03666.13 KFP02460.1 - 0.091 11.5 6.6 0.14 10.9 6.6 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 zf-HC5HC2H PF13771.6 KFP02460.1 - 0.095 13.0 3.1 0.4 11.0 3.0 2.3 1 1 0 1 1 1 0 PHD-like zinc-binding domain CDC45 PF02724.14 KFP02460.1 - 0.24 9.6 9.7 0.24 9.7 9.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Virul_Fac PF10139.9 KFP02460.1 - 0.89 7.7 10.3 1.2 7.3 10.3 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor ALMT PF11744.8 KFP02460.1 - 1.1 8.0 8.3 1.4 7.6 8.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Zip PF02535.22 KFP02460.1 - 1.6 7.9 4.7 1.7 7.7 4.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 KFP02460.1 - 1.7 8.4 13.1 2.5 7.9 13.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 zf-C4pol PF14260.6 KFP02460.1 - 2 8.9 10.4 5.4 7.5 0.9 3.6 3 1 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta Presenilin PF01080.17 KFP02460.1 - 2.4 6.8 12.0 3.3 6.4 12.0 1.2 1 0 0 1 1 1 0 Presenilin Ank_2 PF12796.7 KFP02461.1 - 1.9e-24 86.0 0.6 1.1e-12 48.4 0.3 2.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP02461.1 - 4.2e-16 59.1 0.3 9.1e-08 32.5 0.0 3.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP02461.1 - 7.2e-12 45.3 0.3 9.4e-07 29.0 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KFP02461.1 - 1.8e-11 43.9 0.7 0.00028 21.2 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KFP02461.1 - 3e-09 36.3 0.0 0.0049 17.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat RhoGEF67_u2 PF16614.5 KFP02462.1 - 1.5e-50 169.8 4.4 1.5e-50 169.8 4.4 2.7 2 1 0 2 2 2 1 Unstructured region two on RhoGEF 6 and 7 betaPIX_CC PF16523.5 KFP02462.1 - 3.3e-41 139.0 10.1 3.3e-41 139.0 10.1 3.1 4 0 0 4 4 4 1 betaPIX coiled coil RhoGEF PF00621.20 KFP02462.1 - 1.4e-31 110.2 0.6 1.4e-31 110.2 0.6 2.0 2 0 0 2 2 2 1 RhoGEF domain SH3_9 PF14604.6 KFP02462.1 - 1.2e-17 63.5 0.1 2.4e-17 62.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP02462.1 - 2e-17 62.5 0.2 3.7e-17 61.7 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP02462.1 - 1.1e-16 60.2 0.3 2.3e-16 59.2 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain RhoGEF67_u1 PF16615.5 KFP02462.1 - 3.4e-16 59.5 2.6 3.4e-16 59.5 2.6 3.4 4 0 0 4 4 3 1 Unstructured region one on RhoGEF 6 and 7 PH PF00169.29 KFP02462.1 - 3.3e-08 34.0 0.1 8.6e-08 32.6 0.1 1.7 1 0 0 1 1 1 1 PH domain DUF2057 PF09829.9 KFP02462.1 - 0.036 14.2 0.4 0.096 12.8 0.4 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) AKNA PF12443.8 KFP02462.1 - 0.075 13.7 5.0 0.65 10.7 0.1 3.1 2 0 0 2 2 2 0 AT-hook-containing transcription factor GlutR_dimer PF00745.20 KFP02462.1 - 0.2 12.1 3.5 0.71 10.3 3.5 1.9 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain TCTP PF00838.17 KFP02462.1 - 0.31 11.4 2.8 1 9.6 0.9 2.4 2 0 0 2 2 2 0 Translationally controlled tumour protein CENP-Q PF13094.6 KFP02462.1 - 0.47 10.6 12.1 0.8 9.9 4.7 3.2 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Cnn_1N PF07989.11 KFP02462.1 - 2.2 8.5 8.9 0.26 11.5 3.5 2.4 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 FCH PF00611.23 KFP02462.1 - 4.9 7.5 7.3 1.1 9.6 0.3 3.2 3 0 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain ZapB PF06005.12 KFP02462.1 - 6.7 7.2 13.7 0.32 11.5 6.7 2.5 2 0 0 2 2 2 0 Cell division protein ZapB HLH PF00010.26 KFP02463.1 - 2.5e-05 24.2 0.6 3.2e-05 23.8 0.6 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RhoGAP PF00620.27 KFP02464.1 - 7.7e-48 162.2 0.8 1.5e-47 161.2 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain RhoGAP-FF1 PF16512.5 KFP02464.1 - 6.7e-30 103.6 14.0 2.4e-28 98.6 6.7 4.4 4 0 0 4 4 4 1 p190-A and -B Rho GAPs FF domain Ras PF00071.22 KFP02464.1 - 1.6e-13 50.5 4.1 5.2e-05 22.9 0.4 4.5 4 0 0 4 4 4 4 Ras family FF PF01846.19 KFP02464.1 - 7.5e-13 48.4 16.3 7.5e-10 38.8 1.3 4.9 5 0 0 5 5 5 3 FF domain AAA_22 PF13401.6 KFP02464.1 - 0.0062 16.8 0.1 3.5 7.9 0.1 3.0 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 KFP02464.1 - 0.0064 16.0 0.2 0.023 14.2 0.2 2.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain NOG1 PF06858.14 KFP02464.1 - 0.0072 16.1 0.2 0.022 14.5 0.2 1.9 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) Roc PF08477.13 KFP02464.1 - 0.014 15.6 0.1 0.63 10.3 0.0 3.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KFP02464.1 - 0.062 13.4 0.0 0.42 10.7 0.0 2.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase U5_2-snRNA_bdg PF10597.9 KFP02464.1 - 0.098 12.7 0.9 0.31 11.1 0.2 2.0 2 0 0 2 2 2 0 U5-snRNA binding site 2 of PrP8 SR-25 PF10500.9 KFP02464.1 - 4.2 6.9 13.8 11 5.6 13.8 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ParA PF10609.9 KFP02465.1 - 7.4e-97 323.6 1.0 8.4e-97 323.4 1.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KFP02465.1 - 4.7e-11 42.8 0.0 1.2e-10 41.5 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KFP02465.1 - 2.3e-08 34.1 0.2 3.6e-06 27.0 0.1 2.2 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 KFP02465.1 - 6.2e-07 29.0 0.0 1.1e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 KFP02465.1 - 3.8e-05 23.0 0.6 0.00098 18.4 0.4 2.5 2 1 1 3 3 3 1 Anion-transporting ATPase Fer4_NifH PF00142.18 KFP02465.1 - 0.00085 18.8 0.8 0.0041 16.6 0.8 2.1 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 KFP02465.1 - 0.0025 17.4 0.4 0.0063 16.1 0.1 1.7 2 0 0 2 2 2 1 AAA domain VirC1 PF07015.11 KFP02465.1 - 0.014 14.7 0.1 0.032 13.5 0.0 1.5 2 0 0 2 2 2 0 VirC1 protein AAA_26 PF13500.6 KFP02465.1 - 0.13 12.1 0.6 1.2 8.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain Tyr_Deacylase PF02580.16 KFP02466.1 - 1.1e-29 103.8 0.0 1.3e-29 103.6 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase HEAT PF02985.22 KFP02467.1 - 9.5e-11 41.0 32.0 0.019 15.2 0.7 11.1 11 0 0 11 11 11 4 HEAT repeat HEAT_2 PF13646.6 KFP02467.1 - 3.5e-09 36.9 14.3 1.8 9.0 0.1 8.8 7 1 1 9 9 9 5 HEAT repeats Vac14_Fab1_bd PF12755.7 KFP02467.1 - 0.0001 22.8 0.1 0.002 18.7 0.0 3.3 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KFP02467.1 - 0.018 15.1 6.6 4.1 7.4 0.1 6.0 5 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 OSCP PF00213.18 KFP02467.1 - 0.029 14.5 0.5 0.098 12.8 0.0 2.2 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit HEAT_EZ PF13513.6 KFP02467.1 - 0.035 14.6 29.1 0.43 11.2 0.5 9.4 10 0 0 10 10 10 0 HEAT-like repeat IFRD PF05004.13 KFP02467.1 - 0.15 11.1 18.0 0.39 9.8 0.3 6.4 7 1 0 7 7 7 0 Interferon-related developmental regulator (IFRD) HECT PF00632.25 KFP02468.1 - 5.2e-74 249.5 0.0 1.2e-73 248.3 0.0 1.6 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) BTHB PF18410.1 KFP02468.1 - 1.4e-27 95.3 0.1 2.9e-27 94.3 0.1 1.6 1 0 0 1 1 1 1 Basic tilted helix bundle domain MIB_HERC2 PF06701.13 KFP02468.1 - 1.4e-23 82.9 2.7 3.3e-23 81.7 2.7 1.7 1 0 0 1 1 1 1 Mib_herc2 Sad1_UNC PF07738.13 KFP02468.1 - 2e-23 82.9 0.0 4e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Ank_2 PF12796.7 KFP02468.1 - 1.4e-13 51.2 0.0 1.2e-08 35.4 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP02468.1 - 4.8e-11 42.7 0.0 8.8e-08 32.3 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP02468.1 - 4.1e-08 33.6 0.0 5.1e-06 26.9 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KFP02468.1 - 8.4e-08 32.3 0.0 0.00037 20.8 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 KFP02468.1 - 1.1e-07 31.5 0.0 0.12 13.0 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat F5_F8_type_C PF00754.25 KFP02468.1 - 7.9e-06 26.0 0.1 2.1e-05 24.7 0.1 1.7 1 0 0 1 1 1 1 F5/8 type C domain Clat_adaptor_s PF01217.20 KFP02469.1 - 5.1e-38 130.2 7.6 5.8e-38 130.0 7.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PHD_like PF12910.7 KFP02469.1 - 0.016 15.2 0.7 0.021 14.8 0.7 1.2 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system WD40 PF00400.32 KFP02470.1 - 3.9e-36 122.4 11.0 3e-08 34.2 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Striatin PF08232.12 KFP02470.1 - 6.4e-27 95.1 2.6 6.4e-27 95.1 2.6 2.7 2 1 0 2 2 2 1 Striatin family ANAPC4_WD40 PF12894.7 KFP02470.1 - 6e-08 32.9 0.2 0.11 12.9 0.0 4.8 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP02470.1 - 8.1e-05 21.5 0.3 0.78 8.3 0.0 3.5 4 0 0 4 4 4 2 Nucleoporin Nup120/160 VWA PF00092.28 KFP02471.1 - 9.2e-82 273.5 0.1 5e-42 144.1 0.1 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 KFP02471.1 - 1.3e-27 96.5 0.0 2.8e-12 47.2 0.1 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain LCCL PF03815.19 KFP02471.1 - 8.3e-23 80.3 0.0 2.2e-22 79.0 0.0 1.7 1 0 0 1 1 1 1 LCCL domain VWA_3 PF13768.6 KFP02471.1 - 9.7e-06 25.6 0.0 0.099 12.6 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain Rxt3 PF08642.10 KFP02471.1 - 0.19 12.5 0.0 0.72 10.6 0.0 1.9 1 1 0 1 1 1 0 Histone deacetylation protein Rxt3 Sec1 PF00995.23 KFP02472.1 - 4e-125 419.3 2.0 4.5e-125 419.1 2.0 1.0 1 0 0 1 1 1 1 Sec1 family cwf21 PF08312.12 KFP02472.1 - 0.087 13.0 0.1 0.58 10.4 0.0 2.4 2 0 0 2 2 2 0 cwf21 domain zf-HC5HC2H PF13771.6 KFP02473.1 - 3.8e-19 68.7 4.0 3.8e-19 68.7 4.0 3.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain HECT PF00632.25 KFP02473.1 - 9.9e-11 41.7 0.2 1.8e-10 40.8 0.2 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-HC5HC2H_2 PF13832.6 KFP02473.1 - 2.6e-07 30.8 5.5 2.6e-07 30.8 5.5 3.7 2 1 1 3 3 3 1 PHD-zinc-finger like domain Pkinase PF00069.25 KFP02474.1 - 5.7e-70 235.7 0.0 9e-70 235.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP02474.1 - 1.8e-32 112.6 0.0 3.2e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KFP02474.1 - 3.6e-29 100.4 19.9 1.1e-14 54.0 7.9 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 KFP02474.1 - 1.5e-08 35.1 0.0 1.2e-07 32.2 0.0 2.4 2 0 0 2 2 2 1 PH domain C1_2 PF03107.16 KFP02474.1 - 1.3e-05 25.4 15.0 0.0097 16.2 6.2 2.6 2 0 0 2 2 2 2 C1 domain Kinase-like PF14531.6 KFP02474.1 - 3.5e-05 23.3 0.0 0.00013 21.4 0.0 1.9 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFP02474.1 - 8.4e-05 22.0 0.0 0.00018 21.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KFP02474.1 - 0.11 11.4 0.1 0.17 10.8 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-RING_9 PF13901.6 KFP02474.1 - 0.12 12.3 12.5 1 9.3 0.5 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon PHD PF00628.29 KFP02474.1 - 0.34 10.8 17.7 1.9 8.5 5.3 2.5 2 0 0 2 2 2 0 PHD-finger FYVE_2 PF02318.16 KFP02474.1 - 1.6 9.0 11.0 6.9 6.9 5.5 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger PHD_2 PF13831.6 KFP02474.1 - 7.6 6.2 10.2 12 5.5 0.7 3.0 2 0 0 2 2 2 0 PHD-finger RVT_1 PF00078.27 KFP02475.1 - 0.0055 16.3 0.0 0.0087 15.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 KFP02476.1 - 2e-34 119.1 0.0 2.9e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP02476.1 - 3e-32 111.9 0.0 4.2e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.12 KFP02476.1 - 5.5e-16 57.7 0.7 1.1e-15 56.8 0.7 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.23 KFP02476.1 - 4e-13 50.2 12.1 4e-13 50.2 12.1 2.3 2 0 0 2 2 2 1 Activin types I and II receptor domain Pkinase_fungal PF17667.1 KFP02476.1 - 2e-05 23.5 0.0 3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KFP02476.1 - 0.025 14.2 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KFP02476.1 - 0.069 12.1 0.1 0.15 11.0 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Comm PF15957.5 KFP02476.1 - 0.083 13.2 0.5 1.7 9.0 0.1 2.7 3 0 0 3 3 3 0 Commissureless APH PF01636.23 KFP02476.1 - 0.21 11.5 0.0 0.41 10.5 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family LIM PF00412.22 KFP02477.1 - 2.8e-37 126.8 31.8 1.9e-13 50.4 4.4 3.2 3 0 0 3 3 3 3 LIM domain DUF4749 PF15936.5 KFP02477.1 - 2.3e-10 41.5 0.4 8.5e-10 39.6 0.4 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4749) PDZ PF00595.24 KFP02477.1 - 2.1e-08 34.4 0.3 4.3e-08 33.4 0.3 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP02477.1 - 3.6e-05 23.5 0.0 6.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP02477.1 - 0.0011 19.2 0.1 0.0023 18.2 0.1 1.5 1 0 0 1 1 1 1 PDZ domain 7tm_1 PF00001.21 KFP02478.1 - 7e-53 179.6 16.9 8.3e-53 179.4 16.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP02478.1 - 5.5e-14 52.2 15.8 7.6e-14 51.7 15.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP02478.1 - 4.9e-10 39.5 17.6 7.7e-10 38.8 17.6 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFP02478.1 - 1.4e-05 24.6 9.4 2e-05 24.1 9.4 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFP02478.1 - 0.015 15.0 14.7 0.24 11.1 14.7 2.6 1 1 0 1 1 1 0 Olfactory receptor Git3 PF11710.8 KFP02478.1 - 1.4 8.6 18.3 0.063 13.1 12.6 1.6 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 WTF PF03303.13 KFP02478.1 - 2.4 7.8 10.9 0.11 12.2 3.8 2.0 2 0 0 2 2 2 0 WTF protein DUF3742 PF12553.8 KFP02478.1 - 5.5 7.1 5.7 4.2 7.5 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) WAPL PF07814.13 KFP02479.1 - 4.3e-117 391.0 8.0 6.6e-117 390.4 8.0 1.3 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Wap1 PF16997.5 KFP02479.1 - 0.00043 19.6 4.3 0.007 15.6 0.1 2.5 2 1 0 2 2 2 2 Wap1 domain NARP1 PF12569.8 KFP02479.1 - 0.091 11.6 0.0 0.091 11.6 0.0 2.4 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 ANF_receptor PF01094.28 KFP02480.1 - 0.0041 16.3 0.1 0.0041 16.3 0.1 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region UPF0560 PF10577.9 KFP02481.1 - 1.8e-130 437.0 10.6 8.2e-82 276.0 2.5 2.8 1 1 1 2 2 2 2 Uncharacterised protein family UPF0560 Prominin PF05478.11 KFP02481.1 - 0.00018 19.6 0.1 0.00029 19.0 0.1 1.2 1 0 0 1 1 1 1 Prominin Orthoreo_P10 PF07204.11 KFP02481.1 - 0.3 11.1 1.3 0.43 10.6 0.2 1.8 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 Integrin_alpha2 PF08441.12 KFP02482.1 - 1.2e-123 413.5 0.0 1.4e-123 413.2 0.0 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 KFP02482.1 - 8.6e-30 102.5 19.6 1.6e-09 37.7 0.2 4.6 4 0 0 4 4 4 4 FG-GAP repeat VCBS PF13517.6 KFP02482.1 - 8.2e-16 58.4 8.9 6.6e-06 26.6 1.4 4.8 3 1 2 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.20 KFP02482.1 - 7.8e-05 22.4 0.7 0.00017 21.3 0.7 1.6 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region LYRIC PF15686.5 KFP02482.1 - 0.00016 21.4 0.0 0.00024 20.8 0.0 1.2 1 0 0 1 1 1 1 Lysine-rich CEACAM1 co-isolated protein family DFRP_C PF16543.5 KFP02483.1 - 4.3e-23 81.6 0.8 4.3e-23 81.6 0.8 4.2 4 0 0 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH_4 PF18044.1 KFP02483.1 - 7.7e-09 35.2 6.1 9.7e-07 28.5 1.2 3.3 3 0 0 3 3 3 2 CCCH-type zinc finger Torus PF16131.5 KFP02483.1 - 4.3e-07 30.6 11.8 2e-05 25.3 3.6 3.3 1 1 1 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KFP02483.1 - 1.2e-06 28.4 6.1 1.2e-06 28.4 6.1 3.2 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH PF00642.24 KFP02483.1 - 2.7e-06 27.2 2.6 2.7e-06 27.1 0.9 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KFP02483.1 - 0.0087 16.5 12.4 0.056 13.9 3.9 3.0 2 1 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KFP02483.1 - 0.03 14.5 8.9 0.26 11.5 3.8 3.1 1 1 1 2 2 2 0 Zinc-finger containing family zf-C2H2_jaz PF12171.8 KFP02485.1 - 1.7e-06 28.2 9.2 7.9e-06 26.0 9.2 2.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP02485.1 - 0.005 17.2 2.2 0.005 17.2 2.2 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 KFP02485.1 - 0.21 11.7 6.6 1.1 9.4 6.6 2.3 1 0 0 1 1 1 0 DBF zinc finger Frizzled PF01534.17 KFP02489.1 - 1.5e-139 464.5 20.2 1.8e-139 464.4 20.2 1.0 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region DUF3493 PF11998.8 KFP02489.1 - 0.25 11.5 0.1 0.25 11.5 0.1 1.7 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 Rad60-SLD PF11976.8 KFP02490.1 - 6.3e-22 77.2 0.2 7.5e-22 76.9 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KFP02490.1 - 1.7e-18 66.1 0.7 2.1e-18 65.8 0.7 1.1 1 0 0 1 1 1 1 Ubiquitin family Nop PF01798.18 KFP02491.1 - 7.7e-85 284.0 0.2 1.4e-84 283.2 0.2 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KFP02491.1 - 2.5e-13 50.2 1.4 2.5e-13 50.2 1.4 2.6 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DUF2247 PF10004.9 KFP02491.1 - 0.015 15.1 1.9 0.13 12.0 0.1 2.6 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2247) Pkinase PF00069.25 KFP02492.1 - 8e-33 113.9 0.0 1.5e-32 113.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP02492.1 - 2.5e-29 102.3 0.0 5.5e-29 101.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Activin_recp PF01064.23 KFP02492.1 - 1.4e-11 45.4 7.4 1.4e-11 45.4 7.4 2.1 2 0 0 2 2 2 1 Activin types I and II receptor domain APH PF01636.23 KFP02492.1 - 0.0015 18.5 0.0 0.0037 17.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KFP02492.1 - 0.042 13.5 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 FAM117 PF15388.6 KFP02493.1 - 5.1e-123 410.5 13.1 6.4e-123 410.1 13.1 1.1 1 0 0 1 1 1 1 Protein Family FAM117 CagY_I PF14585.6 KFP02493.1 - 1.4 9.1 5.1 1.7 8.8 2.8 2.3 2 0 0 2 2 2 0 CagY type 1 repeat WD40 PF00400.32 KFP02494.1 - 2.9e-34 116.5 27.5 2.3e-05 25.0 0.9 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat NLE PF08154.12 KFP02494.1 - 8.2e-14 51.9 0.0 1.5e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 KFP02494.1 - 5.8e-05 23.3 4.9 0.015 15.6 0.1 4.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP02494.1 - 0.12 11.0 5.6 2.8 6.5 0.2 2.9 1 1 1 3 3 3 0 Nucleoporin Nup120/160 ALS2CR8 PF15299.6 KFP02495.1 - 9.3e-55 185.9 0.1 1.3e-54 185.4 0.1 1.1 1 0 0 1 1 1 1 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 zf-RING_9 PF13901.6 KFP02496.1 - 6.8e-68 228.7 8.1 1.5e-67 227.6 8.1 1.6 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon PH PF00169.29 KFP02496.1 - 2e-12 47.6 0.3 8.3e-09 35.9 0.0 2.9 3 0 0 3 3 3 2 PH domain PH_13 PF16652.5 KFP02496.1 - 0.019 14.8 0.5 1.1 9.1 0.0 2.8 2 1 1 3 3 3 0 Pleckstrin homology domain MAAL_N PF05034.13 KFP02496.1 - 0.049 13.3 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase N-terminus B12D PF06522.11 KFP02496.1 - 0.098 12.5 0.0 20 5.1 0.0 2.6 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Frizzled PF01534.17 KFP02497.1 - 1.5e-140 467.9 13.9 1.7e-140 467.7 13.9 1.0 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 KFP02497.1 - 8.9e-05 23.1 0.1 0.00022 21.8 0.1 1.7 1 0 0 1 1 1 1 Fz domain DUF1230 PF06799.11 KFP02497.1 - 0.1 12.7 0.5 0.24 11.5 0.0 1.8 2 0 0 2 2 2 0 Conserved in the green lineage and diatoms 27 FxsA PF04186.13 KFP02497.1 - 0.83 9.8 4.8 3.3 7.9 0.0 3.5 3 1 1 4 4 4 0 FxsA cytoplasmic membrane protein Cyclin_N PF00134.23 KFP02498.1 - 8.1e-16 57.9 0.2 1.4e-15 57.1 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KFP02498.1 - 8.9e-11 42.4 0.2 1.2e-10 42.0 0.2 1.4 1 0 0 1 1 1 1 Cyclin Methyltransf_16 PF10294.9 KFP02499.1 - 6.4e-43 146.5 0.0 7.9e-43 146.2 0.0 1.0 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KFP02499.1 - 2.2e-05 24.4 0.0 2.8e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFP02499.1 - 5.7e-05 22.7 0.0 6.9e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KFP02499.1 - 0.00073 19.1 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KFP02499.1 - 0.014 16.0 0.0 0.023 15.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MOR2-PAG1_mid PF14228.6 KFP02499.1 - 0.054 11.1 0.0 0.066 10.9 0.0 1.1 1 0 0 1 1 1 0 Cell morphogenesis central region zf-H2C2_2 PF13465.6 KFP02500.1 - 9.5e-10 38.5 20.8 1.7e-05 25.0 0.7 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFP02500.1 - 7.1e-07 29.3 26.6 0.00013 22.3 0.5 4.0 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP02500.1 - 0.0077 17.0 19.7 0.057 14.3 0.7 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger FOXP-CC PF16159.5 KFP02500.1 - 0.037 14.7 3.6 1.4 9.6 0.4 2.6 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KFP02500.1 - 0.35 11.2 5.8 0.17 12.2 2.6 2.2 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 KFP02500.1 - 6.4 6.6 23.7 0.3 10.9 2.1 4.3 4 1 0 4 4 4 0 C2H2-type zinc-finger domain Peptidase_M14 PF00246.24 KFP02501.1 - 2.7e-89 299.8 0.1 3.3e-89 299.5 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KFP02501.1 - 6.7e-13 48.8 0.2 6.7e-13 48.8 0.2 2.0 2 0 0 2 2 2 1 Carboxypeptidase activation peptide FAST_1 PF06743.15 KFP02502.1 - 2.2e-22 78.8 0.3 2.2e-22 78.8 0.3 4.6 4 3 2 6 6 6 1 FAST kinase-like protein, subdomain 1 RAP PF08373.10 KFP02502.1 - 1e-08 35.1 0.0 2.1e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 RAP domain FAST_2 PF08368.12 KFP02502.1 - 1.7e-08 35.1 0.1 1e-07 32.6 0.0 2.5 2 0 0 2 2 2 1 FAST kinase-like protein, subdomain 2 DUF3781 PF12636.7 KFP02502.1 - 0.041 13.8 0.3 0.54 10.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) Ldh_1_C PF02866.18 KFP02503.1 - 1.2e-12 48.1 0.0 1e-09 38.5 0.0 2.4 2 0 0 2 2 2 2 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glutaredoxin PF00462.24 KFP02503.1 - 0.13 12.5 0.1 1.1 9.5 0.0 2.6 2 0 0 2 2 2 0 Glutaredoxin EF-hand_3 PF09069.11 KFP02504.1 - 1.9e-17 63.4 0.0 2.7e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 EF-hand EF-hand_2 PF09068.11 KFP02504.1 - 0.00083 19.5 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 EF hand DED PF01335.21 KFP02507.1 - 2e-40 136.9 16.3 7.8e-22 77.4 2.1 2.8 3 0 0 3 3 3 2 Death effector domain Peptidase_C14 PF00656.22 KFP02507.1 - 2.8e-38 132.3 0.0 4.2e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.22 KFP02508.1 - 5.3e-44 151.0 0.0 7.9e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 Caspase domain DED PF01335.21 KFP02508.1 - 4.2e-38 129.5 19.7 3.4e-20 72.1 4.0 2.9 3 0 0 3 3 3 2 Death effector domain UBA_6 PF18039.1 KFP02508.1 - 0.79 9.7 2.8 1.6 8.7 0.1 2.6 2 0 0 2 2 2 0 UBA-like domain Pro_isomerase PF00160.21 KFP02509.1 - 1.9e-52 177.7 0.0 2.1e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NIF3 PF01784.18 KFP02510.1 - 1.9e-81 273.3 0.0 2.7e-81 272.8 0.0 1.2 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) ORC2 PF04084.14 KFP02511.1 - 1.4e-105 352.9 0.7 1.9e-105 352.4 0.7 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Hyccin PF09790.9 KFP02512.1 - 6.2e-120 400.1 0.0 8e-120 399.8 0.0 1.1 1 0 0 1 1 1 1 Hyccin NDUF_B12 PF08122.12 KFP02513.1 - 6.8e-22 77.3 1.4 9.4e-22 76.8 1.4 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Pkinase PF00069.25 KFP02514.1 - 4.4e-55 186.9 0.0 5.8e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP02514.1 - 9e-26 90.7 0.0 4.2e-25 88.5 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFP02514.1 - 0.055 13.4 0.4 9.5 6.1 0.0 2.9 3 1 0 3 3 3 0 Phosphotransferase enzyme family CCDC106 PF15794.5 KFP02514.1 - 7.4 6.2 12.0 13 5.4 12.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Shugoshin_C PF07557.11 KFP02515.1 - 2.1e-10 40.2 1.9 3.4e-10 39.5 1.9 1.4 1 0 0 1 1 1 1 Shugoshin C terminus BTB_2 PF02214.22 KFP02516.1 - 9.6e-14 51.5 0.0 4e-13 49.5 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 KFP02516.1 - 0.00083 19.4 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ashwin PF15323.6 KFP02516.1 - 0.15 12.1 3.4 0.28 11.2 3.4 1.4 1 1 0 1 1 1 0 Developmental protein DUF1387 PF07139.11 KFP02517.1 - 4.2e-134 447.2 21.0 4.2e-134 447.2 21.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1387) DUF1296 PF06972.11 KFP02517.1 - 0.37 11.0 5.0 0.12 12.5 1.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1296) Ig_4 PF16680.5 KFP02517.1 - 0.9 9.8 4.0 1.2 9.4 1.5 2.6 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain Tim44 PF04280.15 KFP02518.1 - 0.00015 21.9 0.2 0.00056 20.0 0.1 1.8 2 0 0 2 2 2 1 Tim44-like domain MBA1 PF07961.11 KFP02518.1 - 0.0028 16.8 0.0 0.0041 16.2 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein Cupin_8 PF13621.6 KFP02519.1 - 1.5e-40 139.5 0.0 1.9e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KFP02519.1 - 1.4e-10 41.2 0.0 1.9e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 KFP02519.1 - 0.0073 16.7 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase UPF0565 PF10561.9 KFP02520.1 - 5.1e-93 311.5 0.1 5.9e-93 311.3 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0565 CUT PF02376.15 KFP02521.1 - 2e-48 162.5 2.9 3.3e-24 84.8 0.1 3.3 3 0 0 3 3 3 2 CUT domain CUTL PF16557.5 KFP02521.1 - 1.8e-42 143.4 1.5 1.8e-42 143.4 1.5 3.0 3 0 0 3 3 3 1 CUT1-like DNA-binding domain of SATB ULD PF16534.5 KFP02521.1 - 2.1e-36 124.3 0.0 5.3e-36 123.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-like oligomerisation domain of SATB Homeodomain PF00046.29 KFP02521.1 - 1.6e-06 27.8 0.0 6.1e-06 26.0 0.0 2.1 1 0 0 1 1 1 1 Homeodomain PI-PLC-X PF00388.19 KFP02522.1 - 9.3e-52 174.5 0.0 1.8e-51 173.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFP02522.1 - 9.8e-41 138.7 0.5 2.5e-40 137.4 0.1 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain PH_12 PF16457.5 KFP02522.1 - 3.3e-19 69.7 0.0 9.7e-19 68.2 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain C2 PF00168.30 KFP02522.1 - 7e-18 64.8 0.0 2.4e-17 63.1 0.0 1.9 2 0 0 2 2 2 1 C2 domain EF-hand_like PF09279.11 KFP02522.1 - 3.8e-15 56.2 0.0 1.2e-14 54.6 0.0 1.9 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like PH_14 PF17787.1 KFP02522.1 - 1e-07 31.8 0.1 3.5e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 PH domain EF-hand_7 PF13499.6 KFP02522.1 - 0.0021 18.5 1.5 0.011 16.2 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain pair Mcp5_PH PF12814.7 KFP02522.1 - 0.02 15.0 0.0 0.043 13.9 0.0 1.6 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KFP02522.1 - 0.1 13.1 0.0 0.32 11.5 0.0 1.9 1 0 0 1 1 1 0 PH domain Raftlin PF15250.6 KFP02523.1 - 2.7e-184 613.3 0.0 1.3e-183 611.1 0.0 1.8 1 1 0 1 1 1 1 Raftlin Mob1_phocein PF03637.17 KFP02524.1 - 1.6e-34 119.4 1.5 1.9e-34 119.1 0.9 1.4 1 1 1 2 2 2 1 Mob1/phocein family Cpn10 PF00166.21 KFP02525.1 - 2.3e-30 104.5 0.3 2.5e-30 104.4 0.3 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn60_TCP1 PF00118.24 KFP02526.1 - 1.7e-87 294.1 17.6 4.4e-87 292.8 17.6 1.6 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family 4HB_MCP_1 PF12729.7 KFP02526.1 - 1.1 8.8 5.4 4 6.9 1.8 2.3 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Polyketide_cyc PF03364.20 KFP02527.1 - 3.6e-24 85.4 0.0 4.5e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KFP02527.1 - 0.0027 18.0 0.0 0.0037 17.5 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Ank_2 PF12796.7 KFP02528.1 - 2.3e-164 534.4 78.1 1.3e-19 70.6 1.7 14.9 2 2 10 15 15 15 15 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP02528.1 - 1.8e-152 493.9 58.0 2.8e-14 53.2 0.2 21.5 6 6 18 24 24 24 23 Ankyrin repeats (many copies) Ank PF00023.30 KFP02528.1 - 3.7e-146 469.8 74.8 2.6e-07 30.8 0.1 27.3 27 0 0 27 27 27 25 Ankyrin repeat Ank_5 PF13857.6 KFP02528.1 - 1.9e-117 381.8 62.2 8.8e-11 41.8 0.1 23.0 6 3 18 24 24 24 23 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP02528.1 - 1.2e-115 363.3 54.2 1.7e-06 27.9 0.4 27.2 27 0 0 27 27 27 23 Ankyrin repeat GATase_7 PF13537.6 KFP02528.1 - 0.023 14.6 0.0 97 2.9 0.0 5.9 7 0 0 7 7 7 0 Glutamine amidotransferase domain Ribosomal_S6 PF01250.17 KFP02528.1 - 0.028 14.7 0.0 1.4 9.2 0.0 3.7 3 1 1 4 4 4 0 Ribosomal protein S6 Prok-RING_1 PF14446.6 KFP02528.1 - 9.5 6.2 6.6 6.5 6.8 0.1 4.2 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 DUF4720 PF15846.5 KFP02529.1 - 5.4e-47 157.6 0.1 6.1e-47 157.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4720) HECT PF00632.25 KFP02530.1 - 2e-104 349.4 0.0 3e-104 348.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECW_N PF16562.5 KFP02530.1 - 1.8e-59 198.8 0.0 3.2e-59 198.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 HECW1_helix PF18436.1 KFP02530.1 - 1.1e-36 124.7 2.9 4.7e-35 119.5 1.0 3.1 3 0 0 3 3 3 1 Helical box domain of E3 ubiquitin-protein ligase HECW1 WW PF00397.26 KFP02530.1 - 2e-17 63.0 0.4 1.7e-09 37.6 0.3 2.5 2 0 0 2 2 2 2 WW domain C2 PF00168.30 KFP02530.1 - 6.9e-13 48.8 0.0 1.9e-12 47.3 0.0 1.8 2 0 0 2 2 2 1 C2 domain PPP4R2 PF09184.11 KFP02530.1 - 9.8 5.7 16.1 27 4.2 16.1 1.8 1 0 0 1 1 1 0 PPP4R2 Pkinase PF00069.25 KFP02531.1 - 1.8e-69 234.0 0.0 2.2e-69 233.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP02531.1 - 4.6e-36 124.4 0.0 5.6e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP02531.1 - 0.00091 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFP02531.1 - 0.03 13.9 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KFP02531.1 - 0.033 14.1 0.2 0.065 13.1 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KFP02531.1 - 0.051 12.9 0.0 0.095 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BIR PF00653.21 KFP02532.1 - 2.8e-21 75.9 5.1 2.8e-21 75.9 5.1 1.7 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 KFP02532.1 - 0.0012 18.9 1.2 0.0018 18.3 1.2 1.4 1 0 0 1 1 1 1 C3HC zinc finger-like Zip PF02535.22 KFP02533.1 - 2.4e-101 339.3 18.2 2.4e-101 339.3 18.2 4.7 2 2 1 3 3 3 1 ZIP Zinc transporter Feld-I_B PF09252.10 KFP02533.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Allergen Fel d I-B chain Dicty_REP PF05086.12 KFP02533.1 - 5.9 4.7 6.4 11 3.9 6.4 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Yae1_N PF09811.9 KFP02534.1 - 0.63 9.8 7.0 3.2 7.5 2.0 2.2 1 1 1 2 2 2 0 Essential protein Yae1, N terminal PT PF04886.12 KFP02535.1 - 0.088 12.4 0.0 9 5.9 0.0 3.1 3 0 0 3 3 3 0 PT repeat RVT_1 PF00078.27 KFP02536.1 - 0.0003 20.4 0.0 0.00047 19.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MIF4G PF02854.19 KFP02537.1 - 9.3e-28 97.3 6.2 1.4e-27 96.7 6.2 1.2 1 0 0 1 1 1 1 MIF4G domain Sec34 PF04136.15 KFP02537.1 - 0.04 13.8 2.7 0.08 12.8 2.7 1.5 1 0 0 1 1 1 0 Sec34-like family Cauli_AT PF03233.13 KFP02537.1 - 0.1 12.5 2.8 0.22 11.4 2.8 1.5 1 0 0 1 1 1 0 Aphid transmission protein MH2 PF03166.14 KFP02538.1 - 1.8e-50 171.7 0.4 2.2e-50 171.5 0.4 1.1 1 0 0 1 1 1 1 MH2 domain SH3BP5 PF05276.14 KFP02539.1 - 1e-75 254.5 19.8 1e-75 254.5 19.8 1.4 2 0 0 2 2 2 1 SH3 domain-binding protein 5 (SH3BP5) DUF812 PF05667.11 KFP02539.1 - 0.074 11.9 13.6 0.13 11.2 13.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Exonuc_VII_L PF02601.15 KFP02539.1 - 0.17 11.5 11.5 0.31 10.6 11.5 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Peptidase_C98 PF15499.6 KFP02539.1 - 0.37 10.2 4.9 0.19 11.2 2.5 1.6 1 1 1 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF4735 PF15882.5 KFP02539.1 - 1.4 8.3 7.0 0.86 9.0 1.5 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4735) Phage_GP20 PF06810.11 KFP02539.1 - 1.9 8.3 13.3 0.077 12.8 5.8 2.2 1 1 0 2 2 2 0 Phage minor structural protein GP20 LMBR1 PF04791.16 KFP02539.1 - 4.9 5.9 6.6 8.7 5.1 6.6 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Calpain_III PF01067.22 KFP02540.1 - 8.2e-13 48.8 3.5 1.5e-07 31.7 1.5 3.4 2 2 0 2 2 2 2 Calpain large subunit, domain III Phosphoesterase PF04185.14 KFP02540.1 - 0.054 12.7 0.1 0.069 12.3 0.1 1.1 1 0 0 1 1 1 0 Phosphoesterase family Peptidase_C2 PF00648.21 KFP02541.1 - 1.2e-28 100.0 0.3 3.8e-26 91.8 0.0 2.1 2 0 0 2 2 2 2 Calpain family cysteine protease MIT PF04212.18 KFP02541.1 - 3e-15 56.0 8.3 1.4e-12 47.4 4.8 2.4 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 KFP02541.1 - 0.12 12.7 2.2 0.25 11.7 2.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFP02541.1 - 0.12 12.1 0.1 0.29 10.8 0.1 1.7 1 0 0 1 1 1 0 TPR repeat TPR_8 PF13181.6 KFP02541.1 - 0.17 12.2 1.3 0.46 10.8 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat T2SSF PF00482.23 KFP02541.1 - 0.2 11.6 1.8 0.28 11.1 0.1 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F TPR_2 PF07719.17 KFP02541.1 - 0.23 11.7 0.1 0.23 11.7 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Use1 PF09753.9 KFP02541.1 - 0.89 9.2 9.2 8.8 6.0 9.2 2.0 1 1 0 1 1 1 0 Membrane fusion protein Use1 YtxH PF12732.7 KFP02541.1 - 2.2 8.9 5.7 1.1e+02 3.4 5.7 2.4 1 1 0 1 1 1 0 YtxH-like protein Pkinase PF00069.25 KFP02542.1 - 9.6e-20 71.0 0.0 1.3e-12 47.7 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain WD40 PF00400.32 KFP02542.1 - 1.4e-13 51.0 16.5 4.6e-05 24.1 0.3 6.8 6 0 0 6 6 6 3 WD domain, G-beta repeat HEAT PF02985.22 KFP02542.1 - 1.3e-08 34.3 0.9 0.72 10.3 0.0 5.0 5 0 0 5 5 5 3 HEAT repeat Pkinase_Tyr PF07714.17 KFP02542.1 - 1.5e-06 27.7 0.0 1.2e-05 24.7 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase ANAPC4_WD40 PF12894.7 KFP02542.1 - 0.00038 20.7 0.2 2.2 8.6 0.0 4.4 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 PF13646.6 KFP02542.1 - 0.057 13.8 0.2 2.9 8.4 0.0 3.5 3 2 0 3 3 3 0 HEAT repeats Nucleoporin_N PF08801.11 KFP02542.1 - 0.089 11.5 0.1 13 4.3 0.0 3.1 3 0 0 3 3 3 0 Nup133 N terminal like XPG_I_2 PF12813.7 KFP02543.1 - 5e-08 32.7 0.0 3.5e-06 26.7 0.0 2.4 2 0 0 2 2 2 2 XPG domain containing Pkinase PF00069.25 KFP02544.1 - 2e-61 207.7 0.0 4.9e-61 206.4 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP02544.1 - 3.2e-45 154.4 0.0 9.2e-45 152.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFP02544.1 - 0.16 11.9 0.2 0.36 10.7 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family DHR10 PF18595.1 KFP02544.1 - 7.4 6.7 15.8 1.2 9.2 10.9 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Ribosomal_L3 PF00297.22 KFP02545.1 - 2.3e-54 184.8 0.1 2e-51 175.1 0.1 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 Copine PF07002.16 KFP02546.1 - 1.9e-95 318.4 0.0 2.7e-95 318.0 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 KFP02546.1 - 1.2e-26 93.0 0.1 3e-13 49.9 0.1 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 KFP02546.1 - 3.3e-05 24.1 0.0 5.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 KFP02546.1 - 0.0006 20.1 0.0 0.0012 19.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain His_Phos_2 PF00328.22 KFP02547.1 - 5.1e-34 118.3 2.9 1.8e-32 113.2 2.9 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Rax2 PF12768.7 KFP02547.1 - 0.022 14.2 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity GYF_2 PF14237.6 KFP02548.1 - 1.8e-18 66.1 1.0 4.5e-18 64.8 1.0 1.8 1 0 0 1 1 1 1 GYF domain 2 DnaJ PF00226.31 KFP02548.1 - 3.5e-15 55.9 3.1 5.5e-15 55.2 0.3 2.5 2 0 0 2 2 2 1 DnaJ domain GYF PF02213.16 KFP02548.1 - 0.1 12.3 4.1 0.068 12.9 1.8 2.0 2 0 0 2 2 2 0 GYF domain DUF3361 PF11841.8 KFP02548.1 - 4 7.4 5.5 3.9 7.4 0.6 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) APH PF01636.23 KFP02549.1 - 3.4e-42 145.0 0.1 5.6e-42 144.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.24 KFP02549.1 - 3.6e-33 114.9 0.7 6e-33 114.2 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFP02549.1 - 6.2e-17 61.6 0.0 1.1e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KFP02549.1 - 1.1e-12 48.6 0.1 3e-12 47.2 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KFP02549.1 - 9.5e-12 45.3 0.5 3.9e-11 43.4 0.3 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain EcKinase PF02958.20 KFP02549.1 - 0.0016 17.8 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 KFP02549.1 - 0.0033 17.1 0.0 0.86 9.2 0.0 3.2 3 0 0 3 3 3 1 RIO1 family 7tm_1 PF00001.21 KFP02550.1 - 9.7e-49 166.1 17.1 1.3e-48 165.7 17.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP02550.1 - 2.6e-06 27.0 14.1 3.4e-06 26.6 14.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF621 PF04789.15 KFP02550.1 - 0.0012 18.1 4.8 0.0024 17.1 4.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF621) SirB PF04247.12 KFP02550.1 - 0.0097 16.0 1.0 0.0097 16.0 1.0 2.2 2 0 0 2 2 2 1 Invasion gene expression up-regulator, SirB TMEM108 PF15759.5 KFP02551.1 - 7.6e-136 454.1 8.5 8.6e-136 453.9 8.5 1.0 1 0 0 1 1 1 1 TMEM108 family Filament PF00038.21 KFP02552.1 - 1.1e-55 189.5 25.1 1.3e-55 189.2 25.1 1.0 1 0 0 1 1 1 1 Intermediate filament protein KASH_CCD PF14662.6 KFP02552.1 - 0.0068 16.2 9.2 0.0068 16.2 9.2 3.0 2 2 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH TSC22 PF01166.18 KFP02552.1 - 0.031 14.6 0.2 0.031 14.6 0.2 4.3 4 1 0 4 4 4 0 TSC-22/dip/bun family Baculo_PEP_C PF04513.12 KFP02552.1 - 0.05 13.7 4.9 0.18 11.8 0.2 2.7 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lectin_N PF03954.14 KFP02552.1 - 0.13 12.0 6.5 4.4 7.1 3.0 2.6 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF1759 PF03564.15 KFP02552.1 - 4.8 7.1 7.3 1.7 8.6 0.9 3.0 2 2 2 4 4 4 0 Protein of unknown function (DUF1759) YabA PF06156.13 KFP02552.1 - 8 7.2 22.9 6.4 7.5 0.1 5.0 1 1 3 5 5 5 0 Initiation control protein YabA DivIC PF04977.15 KFP02552.1 - 9.6 6.1 16.4 10 6.0 0.4 4.8 4 1 0 4 4 4 0 Septum formation initiator CDV3 PF15359.6 KFP02553.1 - 2.2e-40 138.1 11.2 3.1e-40 137.6 11.2 1.2 1 0 0 1 1 1 1 Carnitine deficiency-associated protein 3 MecA_N PF05223.11 KFP02553.1 - 0.19 12.0 2.3 3.2 8.0 0.6 2.1 2 0 0 2 2 2 0 NTF2-like N-terminal transpeptidase domain BRCT PF00533.26 KFP02554.1 - 2.1e-43 146.6 1.1 2e-17 63.3 0.1 4.2 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KFP02554.1 - 1.2e-41 140.5 6.8 1.4e-23 82.6 1.4 4.0 4 0 0 4 4 4 3 twin BRCT domain BRCT_2 PF16589.5 KFP02554.1 - 1.5e-18 66.9 0.8 2.3e-08 34.3 0.0 3.7 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KFP02554.1 - 1.1e-14 54.5 0.0 2.7e-07 30.8 0.0 3.4 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 KFP02554.1 - 6.2e-07 29.2 0.0 0.0046 16.8 0.0 3.6 3 0 0 3 3 3 2 Regulator of Ty1 transposition protein 107 BRCT domain 7tm_1 PF00001.21 KFP02555.1 - 1.8e-53 181.6 20.3 2.2e-53 181.2 20.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP02555.1 - 3.3e-09 36.5 22.6 4.3e-09 36.1 22.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Sprouty PF05210.13 KFP02555.1 - 0.12 12.8 1.8 0.66 10.4 0.2 2.4 2 0 0 2 2 2 0 Sprouty protein (Spry) CrgA PF06781.12 KFP02555.1 - 0.13 12.3 1.1 4.3 7.5 0.1 2.7 2 1 0 2 2 2 0 Cell division protein CrgA 7tm_1 PF00001.21 KFP02556.1 - 3.6e-54 183.8 21.6 4.5e-54 183.5 21.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP02556.1 - 6.3e-08 32.3 25.1 8.3e-08 31.9 25.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP02556.1 - 0.00026 20.7 15.7 0.00026 20.7 15.7 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Sprouty PF05210.13 KFP02556.1 - 0.33 11.4 3.7 3 8.3 0.1 2.8 2 1 0 2 2 2 0 Sprouty protein (Spry) COX7C PF02935.16 KFP02556.1 - 1.5 9.1 5.5 3.5 8.0 1.2 3.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc 7tm_1 PF00001.21 KFP02557.1 - 3.9e-53 180.5 23.3 5.1e-53 180.1 23.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP02557.1 - 0.00036 20.0 23.9 0.00049 19.6 23.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx FYVE PF01363.21 KFP02559.1 - 4.6e-16 58.7 18.7 2.2e-15 56.5 18.7 2.3 1 0 0 1 1 1 1 FYVE zinc finger RUN PF02759.19 KFP02559.1 - 3e-08 33.7 0.0 3e-08 33.7 0.0 4.7 4 1 0 4 4 4 1 RUN domain GOLD_2 PF13897.6 KFP02559.1 - 4.8e-05 23.9 0.0 4.8e-05 23.9 0.0 5.6 5 1 1 6 6 6 1 Golgi-dynamics membrane-trafficking Med20 PF08612.11 KFP02559.1 - 0.046 13.1 4.8 0.036 13.4 1.2 2.8 2 0 0 2 2 2 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Ldl_recept_b PF00058.17 KFP02560.1 - 2e-151 492.3 45.1 3.5e-13 49.8 0.0 20.5 20 0 0 20 20 20 20 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 KFP02560.1 - 1.3e-38 131.0 65.0 1.1e-12 48.0 8.1 5.5 5 0 0 5 5 5 4 Coagulation Factor Xa inhibitory site Ldl_recept_a PF00057.18 KFP02560.1 - 9.9e-31 105.7 51.2 4.4e-11 42.8 10.3 4.3 4 0 0 4 4 4 3 Low-density lipoprotein receptor domain class A DUF5050 PF16472.5 KFP02560.1 - 4.6e-23 81.8 0.0 3.2e-05 23.3 0.0 6.0 4 2 2 6 6 6 6 Domain of unknown function (DUF5050) SGL PF08450.12 KFP02560.1 - 2.9e-19 69.6 21.5 0.015 14.9 0.6 11.3 9 3 2 11 11 11 6 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KFP02560.1 - 4.4e-09 36.4 0.0 11 6.3 0.0 8.2 8 1 1 9 9 9 1 Arylesterase EGF PF00008.27 KFP02560.1 - 5.6e-07 29.8 52.0 0.0086 16.4 4.9 5.6 5 0 0 5 5 4 4 EGF-like domain NHL PF01436.21 KFP02560.1 - 0.038 14.1 0.0 15 5.8 0.0 4.9 5 0 0 5 5 5 0 NHL repeat cEGF PF12662.7 KFP02560.1 - 0.06 13.3 22.3 0.035 14.0 1.5 4.9 4 0 0 4 4 4 0 Complement Clr-like EGF-like Methyltransf_12 PF08242.12 KFP02560.1 - 0.099 13.4 0.4 2e+02 2.8 0.0 5.4 5 2 1 6 6 6 0 Methyltransferase domain Insulin_TMD PF17870.1 KFP02560.1 - 0.13 12.4 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Mucin PF01456.17 KFP02561.1 - 0.026 14.5 18.7 0.078 13.0 18.7 1.7 1 1 0 1 1 1 0 Mucin-like glycoprotein Toxin_3 PF00537.18 KFP02561.1 - 0.046 13.9 0.5 0.076 13.2 0.5 1.4 1 0 0 1 1 1 0 Scorpion toxin-like domain SET PF00856.28 KFP02562.1 - 3e-12 47.2 1.3 1.2e-11 45.3 0.1 2.6 2 0 0 2 2 2 1 SET domain CSRNP_N PF16019.5 KFP02562.1 - 0.13 12.2 0.1 0.13 12.2 0.1 3.5 3 0 0 3 3 3 0 Cysteine/serine-rich nuclear protein N-terminus DUF3970 PF13113.6 KFP02562.1 - 1.2 9.4 4.5 0.28 11.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3970) CENP-B_dimeris PF09026.10 KFP02562.1 - 2 8.9 14.0 0.36 11.2 9.2 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Choline_kinase PF01633.20 KFP02563.1 - 1.6e-76 256.7 0.1 2.1e-76 256.2 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KFP02563.1 - 1.3e-10 41.6 0.0 2.2e-10 40.9 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFP02563.1 - 7.7e-08 32.0 0.3 4e-07 29.6 0.3 1.9 1 1 0 1 1 1 1 Ecdysteroid kinase Helo_like_N PF17111.5 KFP02563.1 - 0.034 13.5 0.1 0.056 12.8 0.1 1.3 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Kdo PF06293.14 KFP02563.1 - 0.08 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFP02563.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase LRR_6 PF13516.6 KFP02564.1 - 1.9e-34 114.8 34.1 0.00012 21.8 0.0 12.2 13 0 0 13 13 13 8 Leucine Rich repeat LRR_RI_capping PF18779.1 KFP02564.1 - 9e-17 60.4 3.6 9e-17 60.4 3.6 2.9 3 0 0 3 3 3 1 Capping Ribonuclease inhibitor Leucine Rich Repeat LRR_4 PF12799.7 KFP02564.1 - 1.8e-14 53.6 37.2 0.0005 20.4 0.3 8.5 5 1 4 10 10 10 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP02564.1 - 0.0026 17.5 25.5 6 6.7 2.8 7.7 5 1 2 7 7 7 3 Leucine rich repeat LRR_1 PF00560.33 KFP02564.1 - 0.026 15.0 40.8 4.1 8.3 0.2 11.7 12 1 0 12 12 12 0 Leucine Rich Repeat RabGAP-TBC PF00566.18 KFP02565.1 - 4.9e-54 183.2 6.0 6.7e-54 182.8 6.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3907 PF13047.6 KFP02565.1 - 0.089 12.8 1.5 0.61 10.1 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3907) DUF4890 PF16231.5 KFP02565.1 - 1.9 9.0 8.3 0.27 11.7 3.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4890) Ras PF00071.22 KFP02566.1 - 9.6e-59 197.6 0.0 1.1e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP02566.1 - 8.6e-22 77.6 0.0 1.2e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP02566.1 - 1.1e-09 38.0 0.0 1.4e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP02566.1 - 1.5e-06 27.9 0.2 8.6e-06 25.4 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFP02566.1 - 6.4e-06 26.2 0.0 0.046 13.6 0.0 2.5 2 1 1 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 KFP02566.1 - 1.6e-05 25.0 0.0 2.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFP02566.1 - 0.0037 16.8 0.0 0.032 13.8 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 KFP02566.1 - 0.017 14.5 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Septin PF00735.18 KFP02566.1 - 0.028 13.7 0.0 0.052 12.8 0.0 1.6 1 1 0 1 1 1 0 Septin G-alpha PF00503.20 KFP02566.1 - 0.028 13.6 0.0 1.3 8.1 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit ATP_bind_1 PF03029.17 KFP02566.1 - 0.032 14.0 0.5 0.72 9.6 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KFP02566.1 - 0.13 12.5 0.1 2.4 8.4 0.1 2.4 1 1 1 2 2 2 0 AAA domain Ldh_1_N PF00056.23 KFP02566.1 - 0.15 12.2 0.0 0.44 10.6 0.0 1.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain AAA_25 PF13481.6 KFP02566.1 - 0.16 11.5 0.0 0.39 10.3 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KFP02566.1 - 0.2 12.0 0.1 0.26 11.7 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain LRR_4 PF12799.7 KFP02567.1 - 5.8e-13 48.8 11.3 8.7e-06 26.0 0.2 4.1 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP02567.1 - 3.9e-09 36.1 13.7 1e-05 25.2 3.7 3.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 KFP02567.1 - 1.8e-06 27.5 1.7 3.6e-05 23.3 0.7 2.0 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 KFP02567.1 - 0.0022 17.9 17.0 0.11 12.6 0.2 5.8 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 KFP02567.1 - 0.019 15.4 14.6 4.9 8.1 0.3 5.4 5 1 0 5 5 5 0 Leucine Rich Repeat VWD PF00094.25 KFP02568.1 - 8.3e-30 104.1 0.6 8.3e-30 104.1 0.6 2.1 2 0 0 2 2 2 1 von Willebrand factor type D domain C8 PF08742.11 KFP02568.1 - 2.6e-16 59.8 4.0 2.6e-16 59.8 4.0 5.6 6 0 0 6 6 6 1 C8 domain Cys_knot PF00007.22 KFP02568.1 - 7.7e-11 42.2 18.1 7.7e-11 42.2 18.1 6.1 3 1 2 6 6 6 1 Cystine-knot domain VWC PF00093.18 KFP02568.1 - 4.9e-07 30.0 40.9 2.1e-06 28.0 13.8 8.8 7 1 2 9 9 9 3 von Willebrand factor type C domain TIL PF01826.17 KFP02568.1 - 0.0018 18.5 8.9 0.0018 18.5 8.9 10.5 7 3 2 10 10 10 1 Trypsin Inhibitor like cysteine rich domain VWD PF00094.25 KFP02569.1 - 9.3e-35 120.2 3.2 9.3e-35 120.2 3.2 1.5 2 0 0 2 2 2 1 von Willebrand factor type D domain C8 PF08742.11 KFP02569.1 - 6.1e-19 68.2 16.4 6.1e-19 68.2 16.4 2.2 2 0 0 2 2 2 1 C8 domain VWC PF00093.18 KFP02569.1 - 2.1e-05 24.8 7.1 2.1e-05 24.8 7.1 4.4 4 1 0 4 4 4 1 von Willebrand factor type C domain TIL PF01826.17 KFP02569.1 - 0.0013 18.9 5.4 0.0013 18.9 5.4 5.0 3 1 0 3 3 3 1 Trypsin Inhibitor like cysteine rich domain Pacifastin_I PF05375.13 KFP02569.1 - 0.013 15.2 11.7 0.013 15.2 11.7 4.0 3 1 0 3 3 3 0 Pacifastin inhibitor (LCMII) VWD PF00094.25 KFP02570.1 - 2.3e-35 122.2 2.2 2.3e-35 122.2 2.2 2.9 3 0 0 3 3 3 1 von Willebrand factor type D domain C8 PF08742.11 KFP02570.1 - 2.1e-16 60.1 4.5 2.1e-16 60.1 4.5 5.8 5 1 1 6 6 6 1 C8 domain TIL PF01826.17 KFP02570.1 - 9.4e-06 25.8 12.1 9.4e-06 25.8 12.1 11.2 5 3 4 9 9 9 1 Trypsin Inhibitor like cysteine rich domain VWC PF00093.18 KFP02570.1 - 4.8e-05 23.6 33.7 0.00051 20.3 10.6 9.0 6 3 1 7 7 7 4 von Willebrand factor type C domain VWD PF00094.25 KFP02571.1 - 1.6e-30 106.4 1.5 1.6e-30 106.4 1.5 2.4 2 0 0 2 2 2 1 von Willebrand factor type D domain C8 PF08742.11 KFP02571.1 - 1.2e-18 67.2 15.4 1.2e-18 67.2 15.4 2.7 3 1 0 3 3 3 1 C8 domain VWC PF00093.18 KFP02571.1 - 8.7e-05 22.8 7.9 8.7e-05 22.8 7.9 4.2 4 1 0 4 4 4 1 von Willebrand factor type C domain TIL PF01826.17 KFP02571.1 - 0.0016 18.7 5.9 0.0016 18.7 5.9 4.9 4 1 0 4 4 4 1 Trypsin Inhibitor like cysteine rich domain Pacifastin_I PF05375.13 KFP02571.1 - 0.0022 17.7 14.6 0.0022 17.7 14.6 3.9 3 2 0 3 3 3 1 Pacifastin inhibitor (LCMII) VWD PF00094.25 KFP02572.1 - 1.7e-28 99.9 0.2 2.4e-28 99.4 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.11 KFP02572.1 - 2e-16 60.1 6.8 4.3e-16 59.1 6.8 1.6 1 0 0 1 1 1 1 C8 domain VWD PF00094.25 KFP02573.1 - 1.4e-78 262.6 17.1 9.9e-30 103.9 0.9 3.7 4 0 0 4 4 4 3 von Willebrand factor type D domain C8 PF08742.11 KFP02573.1 - 8.3e-38 128.7 37.5 1.4e-17 63.8 12.8 6.0 6 1 1 7 7 7 3 C8 domain TIL PF01826.17 KFP02573.1 - 4.9e-18 65.1 57.8 9.4e-11 41.8 18.5 9.5 9 2 0 9 9 9 3 Trypsin Inhibitor like cysteine rich domain VWC PF00093.18 KFP02573.1 - 7.8e-06 26.1 19.5 1.3e-05 25.4 3.7 9.5 7 4 1 8 8 8 2 von Willebrand factor type C domain Adaptin_N PF01602.20 KFP02574.1 - 5.2e-146 487.3 4.3 6.6e-146 486.9 4.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KFP02574.1 - 2.4e-45 153.4 0.0 6.2e-45 152.0 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KFP02574.1 - 1e-16 61.2 0.2 2.1e-16 60.2 0.2 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KFP02574.1 - 4.2e-09 36.6 0.4 9.4e-07 29.0 0.0 2.6 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFP02574.1 - 1e-05 25.8 3.9 0.0089 16.4 0.1 4.7 3 1 1 5 5 5 1 HEAT repeats RIX1 PF08167.12 KFP02574.1 - 0.001 18.8 3.1 0.1 12.3 0.2 3.5 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis TIP120 PF08623.10 KFP02574.1 - 0.021 14.6 1.5 3.8 7.2 0.1 2.5 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) IFRD PF05004.13 KFP02574.1 - 1.5 7.8 5.2 0.53 9.3 0.6 2.5 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) Glyco_hydro_18 PF00704.28 KFP02575.1 - 8.2e-20 71.7 0.0 9.8e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Tetraspanin PF00335.20 KFP02576.1 - 1.7e-41 142.5 12.3 1.9e-41 142.3 12.3 1.0 1 0 0 1 1 1 1 Tetraspanin family CD20 PF04103.15 KFP02576.1 - 0.00079 19.5 5.6 0.0016 18.6 5.6 1.5 1 0 0 1 1 1 1 CD20-like family GP38 PF05268.11 KFP02576.1 - 0.043 13.5 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 DUF2207 PF09972.9 KFP02576.1 - 3.6 6.2 4.5 4.5 5.9 4.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RNA_pol_N PF01194.17 KFP02577.1 - 1.3e-33 115.0 0.2 1.5e-33 114.9 0.2 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Tetraspanin PF00335.20 KFP02578.1 - 4.7e-59 199.9 14.3 5.3e-59 199.7 14.3 1.0 1 0 0 1 1 1 1 Tetraspanin family CD20 PF04103.15 KFP02578.1 - 7.1e-07 29.4 4.1 7.1e-07 29.4 4.1 1.7 2 0 0 2 2 2 1 CD20-like family DUF4199 PF13858.6 KFP02578.1 - 7.6e-05 23.2 1.9 7.6e-05 23.2 1.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4199) Baculo_11_kDa PF06143.11 KFP02578.1 - 0.007 15.9 4.1 9.9 5.8 0.3 3.2 3 0 0 3 3 3 2 Baculovirus 11 kDa family EI24 PF07264.11 KFP02578.1 - 0.0078 16.5 1.6 0.016 15.5 1.6 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF996 PF06195.13 KFP02578.1 - 0.051 13.9 5.3 0.12 12.6 3.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF996) DUF2569 PF10754.9 KFP02578.1 - 0.1 13.0 6.5 0.4 11.1 6.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) DUF4500 PF14937.6 KFP02578.1 - 0.13 12.3 2.9 13 5.9 0.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4500) DUF3810 PF12725.7 KFP02578.1 - 0.43 9.9 4.7 0.12 11.7 2.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) DUF373 PF04123.13 KFP02578.1 - 0.89 8.9 6.9 3 7.2 5.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF373) SUR7 PF06687.12 KFP02578.1 - 1.1 8.9 12.8 0.024 14.3 4.7 2.2 2 1 1 3 3 3 0 SUR7/PalI family DUF3139 PF11337.8 KFP02578.1 - 1.6 9.4 6.4 0.18 12.5 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Claudin_2 PF13903.6 KFP02578.1 - 2.6 7.8 14.7 0.37 10.5 5.0 2.7 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Saf_2TM PF18303.1 KFP02578.1 - 4 7.0 5.0 2 8.0 0.6 2.2 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Ras PF00071.22 KFP02579.1 - 4.8e-49 166.1 0.0 5.3e-49 165.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP02579.1 - 9.7e-30 103.3 0.1 1.3e-29 102.9 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP02579.1 - 1e-13 51.2 0.0 1.2e-13 50.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP02579.1 - 4.4e-08 33.2 0.0 5.5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP02579.1 - 8.4e-07 28.7 0.1 2.3e-06 27.3 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFP02579.1 - 9.6e-07 28.4 0.0 1.2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KFP02579.1 - 0.0009 19.2 0.1 0.0071 16.3 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase NTPase_P4 PF11602.8 KFP02579.1 - 0.016 14.4 0.1 0.072 12.3 0.0 1.8 2 0 0 2 2 2 0 ATPase P4 of dsRNA bacteriophage phi-12 SRPRB PF09439.10 KFP02579.1 - 0.018 14.5 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF3067 PF11267.8 KFP02579.1 - 0.061 13.9 0.0 0.086 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3067) Dynamin_N PF00350.23 KFP02579.1 - 0.093 12.8 0.2 5.2 7.1 0.1 2.3 2 0 0 2 2 2 0 Dynamin family AAA_33 PF13671.6 KFP02579.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFP02579.1 - 0.14 11.9 0.1 0.43 10.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFP02579.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region EF-hand_7 PF13499.6 KFP02580.1 - 4.2e-08 33.5 1.0 4.2e-06 27.1 0.3 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP02580.1 - 4.4e-07 29.3 0.1 0.0098 15.8 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KFP02580.1 - 1.9e-06 27.0 0.8 0.029 13.9 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KFP02580.1 - 0.0017 18.2 0.0 0.0059 16.4 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain pair TMEM215 PF15746.5 KFP02580.1 - 0.31 10.5 1.0 0.58 9.6 1.0 1.5 1 0 0 1 1 1 0 TMEM215 family Peptidase_S46 PF10459.9 KFP02580.1 - 4.9 5.7 16.7 8 5.0 16.7 1.4 1 0 0 1 1 1 0 Peptidase S46 Ribosomal_60s PF00428.19 KFP02581.1 - 2.4e-06 28.0 0.1 2.8e-06 27.8 0.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 KFP02581.1 - 0.045 14.1 0.0 0.045 14.1 0.0 1.1 1 0 0 1 1 1 0 EF-hand domain Peptidase_S68 PF10461.9 KFP02582.1 - 6.4e-18 64.6 13.0 1.1e-16 60.7 6.2 2.7 2 0 0 2 2 2 2 Peptidase S68 ZU5 PF00791.20 KFP02582.1 - 1.2e-16 60.8 0.6 2.5e-13 50.2 0.0 2.4 2 0 0 2 2 2 2 ZU5 domain LRR_8 PF13855.6 KFP02582.1 - 1.1e-15 57.1 23.1 2.9e-07 30.1 3.4 5.3 5 1 1 6 6 6 4 Leucine rich repeat Death PF00531.22 KFP02582.1 - 2.5e-13 50.0 0.1 7.3e-13 48.5 0.1 1.8 1 0 0 1 1 1 1 Death domain LRR_4 PF12799.7 KFP02582.1 - 1.1e-09 38.4 23.3 0.025 15.0 0.9 7.2 5 1 3 8 8 8 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP02582.1 - 0.0028 18.0 24.1 3.4 8.6 1.6 7.4 5 1 0 5 5 5 2 Leucine Rich Repeat LRRNT PF01462.18 KFP02582.1 - 2.8 7.7 5.6 1.1 9.0 0.7 2.8 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 KFP02582.1 - 7.9 6.8 21.0 3.3 8.0 0.9 6.2 6 0 0 6 6 6 0 Leucine Rich repeat Mito_carr PF00153.27 KFP02583.1 - 5e-65 215.5 0.5 7.5e-24 83.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Telomere_reg-2 PF10193.9 KFP02583.1 - 0.12 12.8 0.0 0.32 11.5 0.0 1.7 1 0 0 1 1 1 0 Telomere length regulation protein IRF-3 PF10401.9 KFP02584.1 - 1.7e-45 155.0 0.3 2.3e-45 154.6 0.3 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.17 KFP02584.1 - 1.2e-38 131.6 0.1 2.1e-38 130.8 0.1 1.4 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor COR PF16095.5 KFP02585.1 - 0.00017 21.5 0.1 0.00031 20.6 0.1 1.5 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain RA PF00788.23 KFP02586.1 - 5.2e-11 43.0 0.1 1.7e-10 41.4 0.1 1.9 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain TGS PF02824.21 KFP02586.1 - 0.095 12.8 0.0 22 5.2 0.0 2.3 2 0 0 2 2 2 0 TGS domain Cauli_DNA-bind PF03310.13 KFP02586.1 - 0.17 12.0 1.2 0.41 10.7 1.1 1.8 1 1 0 1 1 1 0 Caulimovirus DNA-binding protein SET PF00856.28 KFP02586.1 - 0.19 12.1 0.5 0.29 11.5 0.5 1.3 1 0 0 1 1 1 0 SET domain ATG16 PF08614.11 KFP02586.1 - 0.4 10.9 27.7 0.06 13.6 22.4 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Sec20 PF03908.13 KFP02586.1 - 1.1 9.3 4.7 0.88 9.5 1.7 2.4 2 1 1 3 3 3 0 Sec20 Atg14 PF10186.9 KFP02586.1 - 1.5 7.8 12.7 0.96 8.5 11.2 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 KFP02586.1 - 3.2 7.0 21.1 0.21 10.9 8.8 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 KFP02586.1 - 3.5 7.8 14.2 1.6 8.9 8.5 2.6 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 KFP02586.1 - 5.5 6.2 12.7 11 5.3 12.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 KFP02586.1 - 8.2 5.2 8.0 10 4.9 8.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Sipho_Gp157 PF05565.11 KFP02586.1 - 9.8 6.2 13.8 6.8 6.7 10.9 1.9 1 1 1 2 2 2 0 Siphovirus Gp157 Carn_acyltransf PF00755.20 KFP02587.1 - 6.5e-199 662.4 0.0 7.6e-199 662.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CPT_N PF16484.5 KFP02587.1 - 7.3e-28 96.3 0.2 1.5e-27 95.3 0.2 1.6 1 0 0 1 1 1 1 Carnitine O-palmitoyltransferase N-terminus Galanin PF01296.18 KFP02588.1 - 9.3e-21 73.5 1.4 1.7e-20 72.7 1.4 1.4 1 0 0 1 1 1 1 Galanin GMAP PF06540.11 KFP02588.1 - 9.4e-20 70.4 0.0 1.3e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Galanin message associated peptide (GMAP) SAPS PF04499.15 KFP02589.1 - 7e-105 351.6 13.4 1.5e-66 225.2 8.4 4.0 3 2 1 4 4 4 2 SIT4 phosphatase-associated protein FliC PF12445.8 KFP02589.1 - 0.015 15.7 4.0 0.043 14.2 4.0 1.7 1 0 0 1 1 1 0 Flagellin protein Atx10homo_assoc PF09759.9 KFP02589.1 - 0.026 14.5 3.2 0.073 13.1 0.5 2.9 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain DJ-1_PfpI PF01965.24 KFP02590.1 - 0.00026 20.8 0.1 0.00081 19.2 0.1 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family GATase_5 PF13507.6 KFP02590.1 - 0.0095 15.1 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain IL4 PF00727.18 KFP02590.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Interleukin 4 dUTPase PF00692.19 KFP02591.1 - 1.9e-14 53.5 0.0 2.5e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 dUTPase RVP PF00077.20 KFP02591.1 - 0.01 16.1 0.1 0.028 14.7 0.0 1.8 2 0 0 2 2 2 0 Retroviral aspartyl protease Cornifin PF02389.15 KFP02593.1 - 0.014 15.5 56.7 0.023 14.9 56.7 1.3 1 0 0 1 1 1 0 Cornifin (SPRR) family S_100 PF01023.19 KFP02595.1 - 7.7e-18 63.9 0.4 1.4e-17 63.1 0.1 1.6 2 0 0 2 2 2 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.32 KFP02595.1 - 3.4e-08 32.5 1.4 4.2e-06 25.9 0.4 2.3 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KFP02595.1 - 1.5e-05 24.3 1.5 0.00016 21.0 0.3 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KFP02595.1 - 1.9e-05 25.0 0.2 2.9e-05 24.4 0.2 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP02595.1 - 6.5e-05 22.6 0.5 0.12 12.4 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KFP02595.1 - 8.1e-05 22.4 1.8 0.001 18.9 1.7 2.1 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_11 PF08976.11 KFP02595.1 - 0.023 15.6 0.0 0.028 15.3 0.0 1.1 1 0 0 1 1 1 0 EF-hand domain PORR PF11955.8 KFP02595.1 - 0.046 12.7 0.1 0.05 12.5 0.1 1.0 1 0 0 1 1 1 0 Plant organelle RNA recognition domain EF-hand_4 PF12763.7 KFP02595.1 - 0.051 13.5 0.1 0.066 13.2 0.1 1.3 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand HLH PF00010.26 KFP02596.1 - 5.9e-19 67.8 0.2 5.9e-19 67.8 0.2 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain HTH_51 PF18558.1 KFP02596.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.6 1 1 1 2 2 2 0 Helix-turn-helix domain SecM PF06558.12 KFP02596.1 - 0.15 12.1 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Secretion monitor precursor protein (SecM) DUF4703 PF15775.5 KFP02596.1 - 1.7 8.4 5.1 2.4 7.9 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4703) Strabismus PF06638.11 KFP02597.1 - 6.5e-207 688.1 3.0 2.7e-138 461.8 0.0 2.7 2 1 0 2 2 2 2 Strabismus protein IL28A PF15177.6 KFP02597.1 - 0.028 14.3 0.1 0.048 13.5 0.1 1.3 1 0 0 1 1 1 0 Interleukin-28A V-set PF07686.17 KFP02598.1 - 2.2e-06 27.8 0.0 1.4e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KFP02598.1 - 2.8e-05 24.3 0.5 0.0049 17.2 0.1 2.6 1 1 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 KFP02598.1 - 0.0035 17.9 1.8 0.17 12.5 0.0 3.2 2 1 1 3 3 3 1 Immunoglobulin domain ig PF00047.25 KFP02598.1 - 0.0044 17.2 2.9 0.082 13.1 0.0 3.6 4 1 0 4 4 4 1 Immunoglobulin domain I-set PF07679.16 KFP02598.1 - 0.0074 16.3 0.3 0.065 13.3 0.0 2.6 2 2 0 2 2 2 1 Immunoglobulin I-set domain Izumo-Ig PF16706.5 KFP02598.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain ig PF00047.25 KFP02599.1 - 0.028 14.6 0.1 7.1 6.9 0.1 2.5 2 0 0 2 2 2 0 Immunoglobulin domain SLAM PF06214.11 KFP02599.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Signaling lymphocytic activation molecule (SLAM) protein Ig_3 PF13927.6 KFP02600.1 - 8.8e-33 112.8 4.4 7.3e-12 45.7 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFP02600.1 - 1.5e-24 85.9 1.0 5.7e-08 32.7 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP02600.1 - 1.8e-23 82.7 1.4 2.2e-07 31.1 0.1 3.2 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFP02600.1 - 9e-22 77.1 3.7 1.4e-06 28.3 0.6 3.5 3 1 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.12 KFP02600.1 - 3.8e-17 62.1 0.5 3.8e-17 62.1 0.5 2.6 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFP02600.1 - 2.4e-13 50.2 4.9 1.5e-07 31.6 0.0 4.0 2 1 1 3 3 3 3 Immunoglobulin V-set domain Ig_5 PF16681.5 KFP02600.1 - 1.9e-07 31.4 2.1 0.031 14.7 0.0 4.2 3 2 1 4 4 4 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 KFP02600.1 - 5.4e-07 29.9 1.1 4.2e-06 27.1 0.1 2.6 2 1 0 2 2 2 1 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 KFP02600.1 - 0.0026 17.8 0.0 4.4 7.4 0.0 2.8 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFP02600.1 - 0.011 15.3 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain Syndecan PF01034.20 KFP02600.1 - 0.013 15.4 0.1 0.24 11.3 0.0 2.8 3 0 0 3 3 2 0 Syndecan domain C2-set PF05790.15 KFP02600.1 - 0.025 14.7 5.3 3.4 7.9 0.9 3.6 4 1 0 4 4 4 0 Immunoglobulin C2-set domain Marek_A PF02124.15 KFP02600.1 - 0.23 11.3 1.3 1.4 8.7 0.1 2.3 2 0 0 2 2 2 0 Marek's disease glycoprotein A Ig_3 PF13927.6 KFP02601.1 - 7.5e-51 170.7 0.0 1.3e-13 51.3 0.0 5.8 6 0 0 6 6 6 5 Immunoglobulin domain I-set PF07679.16 KFP02601.1 - 1.9e-40 136.8 0.0 4.4e-12 45.9 0.0 6.0 6 0 0 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP02601.1 - 7e-35 119.2 0.7 5.5e-09 36.2 0.0 5.3 5 0 0 5 5 5 4 Immunoglobulin domain ig PF00047.25 KFP02601.1 - 5.9e-31 106.5 0.5 1.7e-09 37.7 0.1 5.4 5 0 0 5 5 5 3 Immunoglobulin domain fn3 PF00041.21 KFP02601.1 - 1.1e-20 73.7 0.0 5.7e-10 39.4 0.0 3.0 2 0 0 2 2 2 2 Fibronectin type III domain V-set PF07686.17 KFP02601.1 - 8.2e-19 67.8 2.5 0.00053 20.1 0.0 7.4 6 3 1 7 7 7 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP02601.1 - 7e-07 29.2 0.4 0.71 10.0 0.1 3.6 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFP02601.1 - 2.3e-06 27.1 0.0 4.3 7.0 0.0 5.2 5 0 0 5 5 5 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFP02601.1 - 0.00048 20.1 0.0 6.5 6.9 0.0 4.6 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain C2-set PF05790.15 KFP02601.1 - 0.051 13.8 0.2 1.3 9.2 0.0 3.1 3 0 0 3 3 3 0 Immunoglobulin C2-set domain V-set_CD47 PF08204.11 KFP02601.1 - 0.079 12.9 0.1 5.3 7.0 0.0 3.2 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain CH PF00307.31 KFP02602.1 - 1.2e-20 73.7 0.0 1.5e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 KFP02602.1 - 1e-13 50.6 6.2 1e-13 50.6 6.2 1.9 2 0 0 2 2 2 1 Calponin family repeat CDC24 PF06395.11 KFP02602.1 - 0.034 14.4 0.0 0.049 13.9 0.0 1.2 1 0 0 1 1 1 0 CDC24 Calponin TPH PF13868.6 KFP02603.1 - 0.00014 20.5 6.1 0.00017 20.2 6.1 1.1 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain DoxA PF07680.11 KFP02603.1 - 0.082 12.8 0.0 0.096 12.6 0.0 1.1 1 0 0 1 1 1 0 TQO small subunit DoxA DP PF08781.10 KFP02603.1 - 0.12 12.2 1.9 0.11 12.4 1.9 1.1 1 0 0 1 1 1 0 Transcription factor DP Kri1 PF05178.12 KFP02603.1 - 0.12 12.9 2.6 0.13 12.8 2.6 1.2 1 0 0 1 1 1 0 KRI1-like family Porin_3 PF01459.22 KFP02604.1 - 2.3e-28 99.4 0.0 2.7e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin UCH PF00443.29 KFP02605.1 - 2e-11 43.9 0.0 2.3e-11 43.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP02605.1 - 1.1e-09 38.4 0.4 1.3e-09 38.1 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.32 KFP02608.1 - 2.9e-10 40.6 0.6 5.9e-07 30.1 0.5 2.8 3 0 0 3 3 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP02608.1 - 0.01 16.1 0.2 0.27 11.6 0.0 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Presenilin PF01080.17 KFP02608.1 - 0.13 11.0 10.7 0.16 10.7 10.7 1.1 1 0 0 1 1 1 0 Presenilin NARP1 PF12569.8 KFP02608.1 - 0.25 10.2 7.3 0.34 9.8 7.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SDA1 PF05285.12 KFP02608.1 - 0.32 10.4 23.6 0.43 9.9 23.6 1.1 1 0 0 1 1 1 0 SDA1 Zip PF02535.22 KFP02608.1 - 0.38 9.9 2.8 0.45 9.7 2.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter LAP1C PF05609.12 KFP02608.1 - 1.3 8.0 12.8 1.8 7.5 12.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4661 PF15576.6 KFP02608.1 - 1.7 8.5 7.5 2.4 8.0 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) V_ATPase_I PF01496.19 KFP02608.1 - 3 5.6 6.2 3.5 5.4 6.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 KFP02608.1 - 5.2 6.8 15.5 7.6 6.3 15.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 KFP02608.1 - 5.8 5.1 22.4 7.8 4.7 22.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Raftlin PF15250.6 KFP02608.1 - 5.8 5.5 11.3 7.7 5.1 11.3 1.1 1 0 0 1 1 1 0 Raftlin Nop14 PF04147.12 KFP02608.1 - 6.6 4.8 23.7 8.3 4.5 23.7 1.0 1 0 0 1 1 1 0 Nop14-like family SLC12 PF03522.15 KFP02608.1 - 7.6 5.4 8.6 11 4.9 8.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DED PF01335.21 KFP02609.1 - 1.7e-20 73.1 0.1 2.2e-20 72.7 0.1 1.2 1 0 0 1 1 1 1 Death effector domain DUF4381 PF14316.6 KFP02609.1 - 0.079 13.2 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) E1-E2_ATPase PF00122.20 KFP02610.1 - 3.7e-46 156.9 0.4 3.7e-46 156.9 0.4 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFP02610.1 - 2e-20 73.3 0.0 2e-20 73.3 0.0 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFP02610.1 - 5.1e-14 53.1 1.5 2.1e-06 28.2 0.0 3.4 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFP02610.1 - 1.7e-11 44.0 0.0 3.2e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFP02610.1 - 0.00062 19.6 0.4 0.0013 18.6 0.4 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sigma70_r4 PF04545.16 KFP02610.1 - 0.03 13.8 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 DUF742 PF05331.11 KFP02610.1 - 0.18 11.7 0.2 9.3 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF742) IRK_C PF17655.1 KFP02611.1 - 5.1e-65 218.3 0.0 6.6e-65 218.0 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFP02611.1 - 1.1e-57 193.8 1.5 1.5e-57 193.4 1.5 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 KFP02611.1 - 0.0077 16.2 8.6 0.032 14.2 8.5 2.1 1 1 0 1 1 1 1 Ion channel DUF3938 PF13074.6 KFP02611.1 - 2.6 8.4 4.8 1.7 9.0 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) IRK_C PF17655.1 KFP02612.1 - 1e-65 220.6 0.0 1.5e-65 220.0 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFP02612.1 - 8e-58 194.3 0.9 1.4e-57 193.5 0.9 1.4 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain DUF2182 PF09948.9 KFP02612.1 - 0.019 14.8 0.8 0.037 13.9 0.8 1.4 1 0 0 1 1 1 0 Predicted metal-binding integral membrane protein (DUF2182) Ion_trans_2 PF07885.16 KFP02612.1 - 0.041 13.9 3.9 0.093 12.7 3.9 1.7 1 1 0 1 1 1 0 Ion channel Sugar_tr PF00083.24 KFP02613.1 - 8.8e-26 90.8 8.2 1.3e-25 90.2 8.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP02613.1 - 8.6e-20 70.9 29.8 8.6e-20 70.9 29.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily PHD PF00628.29 KFP02614.1 - 3.6e-08 33.2 9.9 3.6e-08 33.2 9.9 2.1 2 1 1 3 3 3 1 PHD-finger PHD_4 PF16866.5 KFP02614.1 - 0.0046 17.0 8.7 0.0046 17.0 8.7 2.1 1 1 1 2 2 2 1 PHD-finger Lar_restr_allev PF14354.6 KFP02614.1 - 0.083 13.3 13.9 33 5.0 13.9 2.5 1 1 0 1 1 1 0 Restriction alleviation protein Lar Inositol_P PF00459.25 KFP02615.1 - 8.7e-54 182.8 0.7 1e-53 182.7 0.7 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Cation_efflux PF01545.21 KFP02616.1 - 2.6e-41 141.6 0.2 7.3e-41 140.1 0.2 1.6 1 1 0 1 1 1 1 Cation efflux family TED_complement PF07678.14 KFP02617.1 - 7.3e-90 301.2 2.4 1.8e-89 299.9 2.4 1.7 1 1 0 1 1 1 1 A-macroglobulin TED domain A2M PF00207.22 KFP02617.1 - 2.5e-29 101.0 1.2 2e-28 98.1 0.3 2.9 3 0 0 3 3 3 1 Alpha-2-macroglobulin family A2M_BRD PF07703.14 KFP02617.1 - 3.1e-25 89.1 1.0 5.3e-22 78.7 0.0 3.6 4 0 0 4 4 4 2 Alpha-2-macroglobulin bait region domain A2M_recep PF07677.14 KFP02617.1 - 5.6e-24 84.7 2.6 2.5e-23 82.6 0.0 3.3 3 0 0 3 3 3 1 A-macroglobulin receptor binding domain NTR PF01759.21 KFP02617.1 - 5.7e-23 80.8 0.1 2.4e-22 78.8 0.1 2.2 1 0 0 1 1 1 1 UNC-6/NTR/C345C module MG1 PF17790.1 KFP02617.1 - 9.5e-23 80.5 2.0 3.8e-22 78.6 1.6 2.3 2 0 0 2 2 2 1 Macroglobulin domain MG1 MG2 PF01835.19 KFP02617.1 - 3.9e-16 59.3 0.1 1.5e-13 51.0 0.0 4.0 4 0 0 4 4 4 1 MG2 domain MG3 PF17791.1 KFP02617.1 - 1.1e-14 54.5 0.1 5.3e-14 52.2 0.1 2.3 1 0 0 1 1 1 1 Macroglobulin domain MG3 ANATO PF01821.18 KFP02617.1 - 2e-11 44.5 8.3 5.2e-11 43.2 8.3 1.8 1 0 0 1 1 1 1 Anaphylotoxin-like domain MG4 PF17789.1 KFP02617.1 - 1.4e-10 41.1 0.1 8.3e-10 38.7 0.1 2.4 1 0 0 1 1 1 1 Macroglobulin domain MG4 Band_7 PF01145.25 KFP02618.1 - 1.2e-27 97.1 2.5 1.5e-27 96.7 2.5 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KFP02618.1 - 0.015 15.0 0.1 0.025 14.3 0.1 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Phlebovirus_G1 PF07243.11 KFP02618.1 - 0.069 11.5 0.1 0.096 11.0 0.1 1.2 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 PG_binding_3 PF09374.10 KFP02618.1 - 0.086 13.1 0.2 0.26 11.6 0.0 1.9 2 0 0 2 2 2 0 Predicted Peptidoglycan domain DUF4476 PF14771.6 KFP02619.1 - 1.8e-31 108.3 2.5 6e-23 81.0 0.7 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4476) NHL PF01436.21 KFP02620.1 - 8.6e-11 41.3 4.1 1e-06 28.5 0.1 5.0 6 0 0 6 6 6 3 NHL repeat SGL PF08450.12 KFP02620.1 - 2.5e-05 24.0 0.3 0.086 12.4 0.0 4.0 3 1 2 5 5 5 2 SMP-30/Gluconolactonase/LRE-like region Tachylectin PF14517.6 KFP02620.1 - 0.0022 17.6 0.1 0.0045 16.6 0.1 1.5 1 0 0 1 1 1 1 Tachylectin Lipase_GDSL_2 PF13472.6 KFP02621.1 - 0.00085 19.8 0.0 0.0031 18.0 0.0 1.9 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 KFP02621.1 - 0.0048 16.2 0.0 0.0089 15.3 0.0 1.3 1 0 0 1 1 1 1 OSK domain Tmemb_cc2 PF10267.9 KFP02621.1 - 0.065 12.4 0.5 0.094 11.8 0.5 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Lipase_GDSL PF00657.22 KFP02621.1 - 0.22 11.5 0.0 0.85 9.6 0.0 1.9 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase MBOAT PF03062.19 KFP02622.1 - 2.8e-30 105.8 10.0 6.9e-30 104.6 10.0 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family KAP_NTPase PF07693.14 KFP02623.1 - 2.4e-108 362.2 0.1 3.4e-108 361.8 0.1 1.2 1 0 0 1 1 1 1 KAP family P-loop domain Ank_2 PF12796.7 KFP02623.1 - 8.8e-75 247.4 2.3 2.1e-13 50.6 0.0 6.8 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP02623.1 - 3.2e-62 205.8 10.0 1.7e-11 44.1 0.4 10.4 2 1 8 10 10 10 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP02623.1 - 2.7e-58 193.6 0.1 1.4e-10 41.5 0.0 8.9 5 1 4 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 KFP02623.1 - 6.7e-55 181.3 2.3 1.9e-06 28.1 0.0 11.8 11 0 0 11 11 11 10 Ankyrin repeat Ank_3 PF13606.6 KFP02623.1 - 3.4e-49 159.1 2.1 8e-06 25.8 0.0 12.4 12 0 0 12 12 12 10 Ankyrin repeat SAM_1 PF00536.30 KFP02623.1 - 0.001 19.4 0.0 0.0047 17.3 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) NACHT PF05729.12 KFP02623.1 - 0.0012 18.8 0.2 0.13 12.2 0.0 2.9 3 0 0 3 3 3 1 NACHT domain ABC2_membrane_2 PF12679.7 KFP02623.1 - 3.8 6.7 7.6 1 8.6 1.9 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein MgtE PF01769.16 KFP02623.1 - 4 7.8 10.1 5.3 7.4 2.8 2.3 2 0 0 2 2 2 0 Divalent cation transporter DUF2207 PF09972.9 KFP02623.1 - 7.6 5.2 6.3 4.3 6.0 0.3 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) HLH PF00010.26 KFP02624.1 - 4.4e-14 52.2 0.4 7.2e-14 51.5 0.4 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain AKNA PF12443.8 KFP02625.1 - 0.021 15.5 0.2 0.021 15.5 0.2 1.1 1 0 0 1 1 1 0 AT-hook-containing transcription factor Sulfotransfer_1 PF00685.27 KFP02627.1 - 1.6e-38 132.8 0.3 2.1e-38 132.3 0.3 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP02627.1 - 3.7e-15 56.9 0.4 6e-10 39.9 0.3 2.3 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFP02627.1 - 0.002 18.1 0.5 0.0059 16.5 0.1 1.8 2 0 0 2 2 2 1 Sulfotransferase family AKAP2_C PF15304.6 KFP02627.1 - 0.14 11.4 0.0 0.57 9.4 0.0 1.8 2 0 0 2 2 2 0 A-kinase anchor protein 2 C-terminus zf-H2C2_5 PF13909.6 KFP02628.1 - 1.1e-05 25.0 0.9 1.1e-05 25.0 0.9 4.1 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KFP02628.1 - 1.8e-05 24.9 0.5 1.8e-05 24.9 0.5 5.6 6 0 0 6 6 6 1 Zinc-finger double domain zf-C2H2 PF00096.26 KFP02628.1 - 0.0017 18.7 31.0 0.23 12.0 0.1 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP02628.1 - 0.24 12.4 29.2 0.92 10.5 2.2 6.0 5 0 0 5 5 5 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KFP02628.1 - 0.64 9.7 9.2 8.4 6.1 0.2 4.8 4 0 0 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zinc_ribbon_15 PF17032.5 KFP02628.1 - 7.8 7.3 17.8 1.7 9.5 1.3 5.1 3 1 1 4 4 4 0 zinc-ribbon family WD40 PF00400.32 KFP02629.1 - 9e-39 130.8 24.7 1.1e-05 26.1 0.2 10.4 10 1 0 10 10 10 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP02629.1 - 1.2e-19 70.4 0.4 1.7e-05 25.0 0.0 6.5 3 3 5 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP02629.1 - 5e-12 46.1 0.4 0.0047 16.8 0.0 5.1 2 1 3 5 5 5 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KFP02629.1 - 0.00024 21.0 1.3 7.4 6.6 0.1 4.9 4 1 1 5 5 5 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KFP02629.1 - 0.00046 19.3 4.6 0.067 12.1 0.0 4.3 3 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 KFP02629.1 - 0.00076 17.6 0.0 0.076 11.0 0.0 3.0 2 1 1 3 3 3 1 IKI3 family PQQ PF01011.21 KFP02629.1 - 0.0058 16.5 0.1 0.024 14.5 0.1 2.1 1 0 0 1 1 1 1 PQQ enzyme repeat BBS2_Mid PF14783.6 KFP02629.1 - 0.0064 16.5 0.0 0.15 12.1 0.0 3.0 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 KFP02629.1 - 0.081 11.6 0.0 0.51 8.9 0.1 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Sugar_tr PF00083.24 KFP02630.1 - 8.8e-109 364.4 25.9 1e-108 364.1 25.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP02630.1 - 2.4e-29 102.4 41.7 1.6e-22 79.9 22.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily 7tm_1 PF00001.21 KFP02631.1 - 4.7e-74 249.0 15.8 5.8e-74 248.7 15.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP02631.1 - 3.2e-12 46.4 12.6 2.7e-11 43.3 12.6 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP02631.1 - 1.3e-06 28.2 18.3 1.6e-06 28.0 11.4 2.7 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx Otopetrin PF03189.13 KFP02632.1 - 5e-48 164.0 21.6 5e-20 71.8 6.2 3.8 2 1 0 3 3 3 3 Otopetrin DUF1345 PF07077.11 KFP02632.1 - 0.088 12.5 1.4 0.61 9.8 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) zf-LYAR PF08790.11 KFP02634.1 - 2.3e-14 52.9 2.0 2.3e-14 52.9 2.0 2.6 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-ACC PF17848.1 KFP02634.1 - 7.2e-06 26.0 4.1 3e-05 24.0 4.1 2.2 1 0 0 1 1 1 1 Acetyl-coA carboxylase zinc finger domain zf_UBZ PF18439.1 KFP02634.1 - 0.14 11.7 2.5 7.8 6.2 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger CDC45 PF02724.14 KFP02634.1 - 0.16 10.2 17.5 0.24 9.6 17.5 1.4 1 0 0 1 1 1 0 CDC45-like protein IBR PF01485.21 KFP02634.1 - 4.3 7.6 12.5 13 6.1 12.5 1.9 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-H2C2_2 PF13465.6 KFP02635.1 - 6.6e-45 149.6 51.6 7.3e-09 35.7 3.8 8.3 8 0 0 8 8 7 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFP02635.1 - 9.1e-37 123.5 49.5 5.4e-06 26.6 1.1 7.9 7 0 0 7 7 7 7 Zinc finger, C2H2 type BTB PF00651.31 KFP02635.1 - 2.2e-25 89.0 0.8 4.3e-25 88.1 0.8 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.6 KFP02635.1 - 4.3e-24 83.1 48.5 0.00086 20.0 0.9 8.3 8 0 0 8 8 7 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP02635.1 - 3.8e-15 55.7 30.8 0.0032 17.7 0.7 8.4 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP02635.1 - 1.4e-12 47.3 51.4 6.9e-05 22.7 0.3 7.5 7 0 0 7 7 7 4 C2H2-type zinc finger zf-met PF12874.7 KFP02635.1 - 3.2e-10 40.1 44.0 0.0052 17.1 0.6 8.6 9 0 0 9 9 9 5 Zinc-finger of C2H2 type zf_UBZ PF18439.1 KFP02635.1 - 1.7e-07 30.7 23.7 1 9.0 0.1 7.6 7 0 0 7 7 7 3 Ubiquitin-Binding Zinc Finger GAGA PF09237.11 KFP02635.1 - 0.00016 21.4 20.6 0.22 11.4 0.1 6.4 3 2 4 7 7 7 3 GAGA factor Zn-ribbon_8 PF09723.10 KFP02635.1 - 0.0059 16.7 27.4 0.53 10.4 1.9 5.4 2 2 4 6 6 6 4 Zinc ribbon domain zf-C2H2_11 PF16622.5 KFP02635.1 - 0.0079 15.9 40.6 0.0082 15.9 1.5 7.2 8 0 0 8 8 7 3 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KFP02635.1 - 0.009 16.7 21.2 0.74 10.5 0.3 5.9 1 1 2 4 4 4 2 Zinc finger C2H2-type, 3 repeats zf-C2HC_2 PF13913.6 KFP02635.1 - 0.041 13.8 30.3 0.47 10.4 0.5 7.3 7 0 0 7 7 7 0 zinc-finger of a C2HC-type zf-MYST PF17772.1 KFP02635.1 - 0.29 10.8 17.5 18 5.1 0.1 5.9 5 2 1 6 6 6 0 MYST family zinc finger domain BolA PF01722.18 KFP02635.1 - 0.35 11.2 5.9 12 6.2 0.3 4.3 1 1 0 2 2 2 0 BolA-like protein ADK_lid PF05191.14 KFP02635.1 - 0.59 10.2 15.1 7.5 6.6 0.0 4.9 3 1 1 4 4 4 0 Adenylate kinase, active site lid zf-RING_7 PF02591.15 KFP02635.1 - 0.91 9.8 0.0 0.91 9.8 0.0 5.2 7 0 0 7 7 5 0 C4-type zinc ribbon domain zinc_ribbon_15 PF17032.5 KFP02635.1 - 1 10.2 26.3 1.8 9.4 0.3 5.1 3 2 0 5 5 5 0 zinc-ribbon family DUF3268 PF11672.8 KFP02635.1 - 2.7 8.4 17.7 3.5 8.0 0.4 4.4 2 2 1 4 4 4 0 zinc-finger-containing domain FYVE PF01363.21 KFP02635.1 - 7.5 6.8 37.6 4.8 7.4 0.7 5.4 1 1 4 5 5 5 0 FYVE zinc finger Calcyon PF06387.11 KFP02636.1 - 6e-88 293.6 0.2 6.9e-88 293.4 0.2 1.0 1 0 0 1 1 1 1 D1 dopamine receptor-interacting protein (calcyon) MgsA_C PF12002.8 KFP02636.1 - 0.052 13.5 0.3 0.094 12.7 0.3 1.4 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal zf-LITAF-like PF10601.9 KFP02636.1 - 0.25 11.6 1.5 0.27 11.5 0.2 1.6 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Syntaxin-18_N PF10496.9 KFP02637.1 - 4.2e-24 84.6 0.5 4.2e-24 84.6 0.5 2.2 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus Phage_Integr_2 PF13009.6 KFP02637.1 - 0.032 13.4 0.8 0.055 12.6 0.8 1.4 1 0 0 1 1 1 0 Putative phage integrase Prominin PF05478.11 KFP02637.1 - 0.47 8.3 3.9 1.2 7.0 0.2 2.4 2 1 1 3 3 3 0 Prominin ISG65-75 PF11727.8 KFP02637.1 - 1.1 8.5 4.8 1.4 8.1 0.4 2.3 2 0 0 2 2 2 0 Invariant surface glycoprotein Homeodomain PF00046.29 KFP02638.1 - 1.5e-21 76.0 4.7 2.3e-21 75.4 4.7 1.3 1 0 0 1 1 1 1 Homeodomain DUF2457 PF10446.9 KFP02638.1 - 1 8.4 9.7 1.2 8.1 9.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CYTL1 PF15153.6 KFP02639.1 - 2.2e-55 186.0 3.3 2.5e-55 185.9 3.3 1.0 1 0 0 1 1 1 1 Cytokine-like protein 1 PET PF06297.14 KFP02640.1 - 2.5e-41 139.9 2.7 4.2e-41 139.1 2.7 1.4 1 0 0 1 1 1 1 PET Domain LIM PF00412.22 KFP02640.1 - 3.9e-26 91.1 59.6 1.9e-13 50.4 7.1 4.9 4 2 0 4 4 4 3 LIM domain SHIRT PF18655.1 KFP02640.1 - 0.029 15.0 0.7 1.3 9.7 0.1 2.4 2 0 0 2 2 2 0 SHIRT domain DUF530 PF04409.12 KFP02640.1 - 0.16 10.3 0.4 0.25 9.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF530) DUF3371 PF11851.8 KFP02641.1 - 3.7e-34 118.6 5.6 3.7e-34 118.6 5.6 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3371) HLH PF00010.26 KFP02641.1 - 1.4e-15 57.0 0.3 3.1e-15 55.9 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MITF_TFEB_C_3_N PF15951.5 KFP02641.1 - 1.7e-13 51.5 1.6 1.7e-13 51.5 1.6 2.4 2 1 0 2 2 2 1 MITF/TFEB/TFEC/TFE3 N-terminus Lipase_GDSL_2 PF13472.6 KFP02642.1 - 0.00085 19.8 0.0 0.0031 18.0 0.0 1.9 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 KFP02642.1 - 0.0048 16.2 0.0 0.0089 15.3 0.0 1.3 1 0 0 1 1 1 1 OSK domain Tmemb_cc2 PF10267.9 KFP02642.1 - 0.065 12.4 0.5 0.094 11.8 0.5 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Lipase_GDSL PF00657.22 KFP02642.1 - 0.22 11.5 0.0 0.85 9.6 0.0 1.9 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase MDFI PF15316.6 KFP02643.1 - 1.3e-71 240.2 36.5 2e-71 239.6 36.5 1.3 1 0 0 1 1 1 1 MyoD family inhibitor Forkhead PF00250.18 KFP02644.1 - 2.7e-36 123.7 0.0 3.1e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 Forkhead domain Linker_histone PF00538.19 KFP02644.1 - 0.043 14.2 0.0 0.065 13.6 0.0 1.3 1 0 0 1 1 1 0 linker histone H1 and H5 family CBM_21 PF03370.13 KFP02645.1 - 3.6e-28 98.0 0.2 7.7e-28 96.9 0.2 1.6 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KFP02645.1 - 4.1e-07 30.5 0.2 1.5e-06 28.7 0.2 2.0 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) DUF4730 PF15873.5 KFP02647.1 - 5.2e-22 77.9 2.8 5.9e-22 77.7 2.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4730) Antimicrobial10 PF08105.11 KFP02647.1 - 0.44 10.7 3.6 0.28 11.3 1.9 1.6 1 1 1 2 2 2 0 Metchnikowin family Bmt2 PF11968.8 KFP02648.1 - 5.9e-08 32.8 0.4 2.9e-05 24.0 0.3 2.1 1 1 1 2 2 2 2 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 COX7a PF02238.15 KFP02649.1 - 0.45 10.9 3.1 5.7 7.4 0.3 2.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII DUF4577 PF15145.6 KFP02650.1 - 1.5e-44 151.1 0.2 1.7e-44 150.9 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4577) MscL PF01741.18 KFP02650.1 - 0.0048 17.2 1.3 0.0057 17.0 1.3 1.2 1 1 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL Cadherin_C_2 PF16492.5 KFP02650.1 - 0.01 16.5 0.1 0.02 15.6 0.1 1.6 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal BatD PF13584.6 KFP02650.1 - 0.037 12.8 0.0 0.04 12.7 0.0 1.0 1 0 0 1 1 1 0 Oxygen tolerance DUF5305 PF17231.2 KFP02650.1 - 0.039 13.4 0.6 0.064 12.6 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5305) COX2_TM PF02790.15 KFP02650.1 - 0.053 13.7 0.1 0.072 13.2 0.1 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain DUF2976 PF11190.8 KFP02650.1 - 0.055 13.3 0.1 0.085 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) Tetraspanin PF00335.20 KFP02650.1 - 0.12 12.0 0.3 0.16 11.6 0.3 1.1 1 0 0 1 1 1 0 Tetraspanin family IFRD PF05004.13 KFP02651.1 - 8.5e-110 366.6 5.8 1e-109 366.4 5.8 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.12 KFP02651.1 - 3.3e-24 85.2 0.7 3.3e-24 85.2 0.7 2.2 2 0 0 2 2 2 1 Interferon-related protein conserved region HEAT PF02985.22 KFP02651.1 - 0.018 15.2 0.4 13 6.3 0.1 3.1 3 0 0 3 3 3 0 HEAT repeat zf-C2H2_2 PF12756.7 KFP02652.1 - 5.7e-42 142.2 24.5 7.1e-24 84.1 6.4 3.3 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFP02652.1 - 2.3e-10 40.4 21.2 0.0011 19.7 0.4 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP02652.1 - 0.00011 22.3 3.4 0.00011 22.3 3.4 4.3 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KFP02652.1 - 0.00042 20.6 1.6 0.00042 20.6 1.6 5.3 5 1 0 5 5 5 2 Zinc finger, C2H2 type zf-BED PF02892.15 KFP02652.1 - 0.0053 16.7 0.3 0.0053 16.7 0.3 5.1 5 0 0 5 5 5 2 BED zinc finger zf-C2H2_11 PF16622.5 KFP02652.1 - 0.017 14.9 11.0 0.52 10.1 1.7 3.8 3 0 0 3 3 3 0 zinc-finger C2H2-type PyrI_C PF02748.15 KFP02652.1 - 0.066 13.1 0.6 0.066 13.1 0.6 4.8 5 0 0 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-met PF12874.7 KFP02652.1 - 0.066 13.6 1.3 0.066 13.6 1.3 4.0 4 1 0 4 4 4 0 Zinc-finger of C2H2 type YokU PF14122.6 KFP02652.1 - 0.12 12.4 0.1 0.12 12.4 0.1 3.1 4 0 0 4 4 4 0 YokU-like protein, putative antitoxin DOCK_N PF16172.5 KFP02653.1 - 1.6e-102 343.3 0.1 3.1e-102 342.3 0.1 1.5 1 0 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 KFP02653.1 - 5.2e-90 302.6 11.3 2.6e-88 297.0 11.3 3.0 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 KFP02653.1 - 1.2e-53 181.8 0.0 3e-52 177.3 0.0 2.7 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins SH3_1 PF00018.28 KFP02653.1 - 0.00085 18.9 0.0 0.0018 17.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP02653.1 - 0.0014 18.4 0.0 0.0033 17.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP02653.1 - 0.0023 17.6 0.1 0.0077 15.9 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain Peptidase_S24 PF00717.23 KFP02654.1 - 1.4e-09 37.7 0.3 2.7e-09 36.8 0.3 1.5 1 1 0 1 1 1 1 Peptidase S24-like DUF2798 PF11391.8 KFP02654.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) LRR_8 PF13855.6 KFP02655.1 - 2.8e-40 135.9 35.4 8.6e-15 54.3 4.7 7.0 2 1 6 8 8 8 7 Leucine rich repeat LRR_5 PF13306.6 KFP02655.1 - 4.6e-22 78.3 0.1 1.8e-08 34.4 0.0 3.6 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFP02655.1 - 2.9e-21 75.2 45.6 0.00013 22.3 3.9 8.4 4 2 1 7 7 7 6 Leucine Rich repeats (2 copies) I-set PF07679.16 KFP02655.1 - 6.8e-13 48.5 0.0 4.2e-12 46.0 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP02655.1 - 1.7e-12 47.7 0.0 5.1e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.6 KFP02655.1 - 2.5e-10 40.2 23.9 7.3e-05 22.3 0.6 4.5 1 1 4 5 5 5 4 Leucine-rich repeat ig PF00047.25 KFP02655.1 - 1.6e-08 34.6 0.0 3.5e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.21 KFP02655.1 - 9.4e-08 32.3 0.1 2e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Ig_2 PF13895.6 KFP02655.1 - 1.4e-06 28.5 0.2 4.5e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain LRRCT PF01463.24 KFP02655.1 - 0.0019 18.6 0.1 0.0048 17.3 0.1 1.8 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain V-set PF07686.17 KFP02655.1 - 0.0029 17.7 0.2 0.39 10.9 0.1 2.8 1 1 0 1 1 1 1 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 KFP02655.1 - 0.029 14.9 0.1 0.073 13.7 0.1 1.6 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain LRRNT PF01462.18 KFP02655.1 - 0.47 10.1 7.4 0.07 12.8 1.1 3.0 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KFP02655.1 - 7.5 7.5 35.2 13 6.8 0.6 10.5 12 1 0 12 12 10 0 Leucine Rich Repeat DnaJ PF00226.31 KFP02656.1 - 1.6e-28 98.6 2.2 2.7e-28 97.9 2.2 1.4 1 0 0 1 1 1 1 DnaJ domain THAP PF05485.12 KFP02657.1 - 7e-13 49.3 0.2 1.9e-12 48.0 0.2 1.7 1 0 0 1 1 1 1 THAP domain CENP-R PF06729.12 KFP02657.1 - 0.21 11.5 3.8 0.47 10.4 0.3 2.5 2 0 0 2 2 2 0 Kinetochore component, CENP-R RVT_1 PF00078.27 KFP02658.1 - 0.027 14.0 0.0 0.095 12.2 0.0 1.9 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Trypsin PF00089.26 KFP02659.1 - 5.3e-49 167.0 0.0 5.9e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFP02659.1 - 4.5e-05 23.8 0.0 7.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF2905 PF11146.8 KFP02659.1 - 0.12 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2905) Trypsin_2 PF13365.6 KFP02659.1 - 0.16 12.9 0.0 0.62 10.9 0.0 1.9 1 1 0 1 1 1 0 Trypsin-like peptidase domain Sox17_18_mid PF12067.8 KFP02660.1 - 2.6e-21 75.4 5.2 8.7e-21 73.7 5.2 1.9 1 0 0 1 1 1 1 Sox 17/18 central domain HMG_box PF00505.19 KFP02660.1 - 4.4e-08 33.4 0.4 7.9e-08 32.6 0.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP02660.1 - 0.0035 17.9 0.1 0.0073 16.9 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain G-patch PF01585.23 KFP02661.1 - 9.9e-17 60.6 3.4 1.6e-16 59.9 3.4 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFP02661.1 - 2.6e-09 37.0 2.6 4.3e-09 36.3 1.2 2.0 2 0 0 2 2 2 1 G-patch domain DUF3437 PF11919.8 KFP02661.1 - 0.18 11.7 3.5 1.5 8.8 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) XK-related PF09815.9 KFP02662.1 - 1.2e-100 336.9 21.2 1.4e-100 336.7 21.2 1.0 1 0 0 1 1 1 1 XK-related protein ECF_trnsprt PF12822.7 KFP02662.1 - 0.063 13.4 7.4 0.12 12.5 7.4 1.5 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Meleagrin PF08189.11 KFP02663.1 - 5.8e-22 77.1 14.4 7e-22 76.8 14.4 1.1 1 0 0 1 1 1 1 Meleagrin/Cygnin family DIM PF08194.12 KFP02663.1 - 0.036 14.3 1.6 0.075 13.2 1.6 1.5 1 0 0 1 1 1 0 DIM protein Meleagrin PF08189.11 KFP02664.1 - 3.2e-23 81.1 17.1 3.9e-23 80.9 17.1 1.1 1 0 0 1 1 1 1 Meleagrin/Cygnin family Meleagrin PF08189.11 KFP02665.1 - 3.1e-22 78.0 14.4 3.7e-22 77.7 14.4 1.1 1 0 0 1 1 1 1 Meleagrin/Cygnin family Myotub-related PF06602.14 KFP02666.1 - 1.7e-78 264.0 4.6 2.1e-78 263.8 4.6 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Hydrolase_6 PF13344.6 KFP02666.1 - 0.099 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Epimerase PF01370.21 KFP02667.1 - 4.1e-18 65.7 0.0 5.3e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFP02667.1 - 6.9e-13 48.7 0.0 1.2e-12 47.9 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KFP02667.1 - 1e-07 31.4 0.0 1.3e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KFP02667.1 - 1.7e-07 30.5 0.0 2.6e-07 29.9 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KFP02667.1 - 8.8e-05 21.8 0.0 0.0067 15.6 0.2 2.7 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KFP02667.1 - 0.00056 19.2 0.6 0.0045 16.2 0.0 2.4 2 1 0 2 2 2 1 Male sterility protein KR PF08659.10 KFP02667.1 - 0.035 14.0 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 KR domain FAM167 PF11652.8 KFP02669.1 - 5.2e-38 129.4 2.3 9.8e-38 128.5 2.3 1.5 1 0 0 1 1 1 1 FAM167 LURAP PF14854.6 KFP02669.1 - 0.0031 17.5 0.3 0.0058 16.6 0.3 1.4 1 0 0 1 1 1 1 Leucine rich adaptor protein DUF2388 PF09498.10 KFP02669.1 - 0.056 13.4 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) CEP209_CC5 PF16574.5 KFP02669.1 - 0.074 13.2 3.2 0.29 11.3 0.3 2.2 2 0 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 DUF4530 PF15039.6 KFP02669.1 - 0.17 12.0 2.8 0.2 11.8 2.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4530) ERM PF00769.19 KFP02669.1 - 1.7 8.4 7.9 9.9 5.9 7.8 2.2 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Dapper PF15268.6 KFP02669.1 - 2.2 7.1 5.7 2.8 6.7 5.7 1.4 1 1 0 1 1 1 0 Dapper Pkinase_Tyr PF07714.17 KFP02670.1 - 4e-64 216.4 0.0 4.9e-61 206.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFP02670.1 - 4.3e-27 95.1 0.0 1.1e-25 90.5 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain SH2 PF00017.24 KFP02670.1 - 1.8e-25 88.9 0.1 2.9e-25 88.2 0.1 1.4 1 0 0 1 1 1 1 SH2 domain Haspin_kinase PF12330.8 KFP02670.1 - 0.027 13.4 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain SPRY PF00622.28 KFP02672.1 - 4.8e-18 65.4 0.4 1.1e-17 64.3 0.4 1.6 1 1 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.6 KFP02672.1 - 1.7e-08 34.1 14.1 1.7e-08 34.1 14.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP02672.1 - 7.3e-05 22.5 10.7 0.00023 21.0 10.7 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Nefa_Nip30_N PF10187.9 KFP02673.1 - 6e-32 110.1 22.9 1.3e-31 109.1 22.9 1.6 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Herpes_UL92 PF03048.14 KFP02673.1 - 0.18 11.5 0.2 0.32 10.8 0.2 1.3 1 0 0 1 1 1 0 UL92 family Copine PF07002.16 KFP02674.1 - 1.4e-89 299.2 0.0 2.2e-89 298.6 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.30 KFP02674.1 - 2.6e-26 91.9 0.0 8.8e-13 48.4 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 KFP02674.1 - 7.8e-06 26.1 0.0 1.6e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 KFP02674.1 - 0.092 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain Oxidored_q3 PF00499.20 KFP02675.1 - 3.6e-12 46.2 9.8 3.6e-12 46.2 9.8 1.3 2 0 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 LBP_BPI_CETP PF01273.25 KFP02676.1 - 1.2e-27 96.5 0.4 2.9e-27 95.3 0.0 1.8 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP_C PF02886.17 KFP02676.1 - 4.6e-27 95.0 1.1 1.2e-25 90.4 0.2 2.2 2 0 0 2 2 2 2 LBP / BPI / CETP family, C-terminal domain ubiquitin PF00240.23 KFP02677.1 - 0.0043 16.8 0.5 0.0098 15.6 0.5 1.7 1 0 0 1 1 1 1 Ubiquitin family Glycoprotein PF03409.15 KFP02677.1 - 0.18 10.6 0.3 0.25 10.1 0.3 1.2 1 0 0 1 1 1 0 Transmembrane glycoprotein Pex14_N PF04695.13 KFP02677.1 - 0.22 12.1 6.8 0.083 13.6 1.3 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PB1 PF00564.24 KFP02678.1 - 2.8e-12 46.4 0.3 6.2e-12 45.3 0.0 1.6 2 0 0 2 2 2 1 PB1 domain PDZ PF00595.24 KFP02678.1 - 2.2e-11 44.0 0.3 4.4e-11 43.0 0.2 1.6 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFP02678.1 - 1.5e-07 31.1 0.1 3.4e-07 30.0 0.1 1.6 1 0 0 1 1 1 1 PDZ domain Enkurin PF13864.6 KFP02679.1 - 1.2e-26 92.9 3.2 1.2e-26 92.9 3.2 2.9 3 0 0 3 3 3 1 Calmodulin-binding DUF2262 PF10020.9 KFP02679.1 - 0.14 12.6 0.1 0.14 12.6 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2262) GFO_IDH_MocA PF01408.22 KFP02680.1 - 1.3e-14 55.0 0.0 5.8e-14 52.9 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 KFP02680.1 - 0.00074 20.0 0.0 0.0026 18.3 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent PmbA_TldD PF01523.16 KFP02680.1 - 0.036 13.9 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative modulator of DNA gyrase Shikimate_DH PF01488.20 KFP02680.1 - 0.065 13.3 0.0 0.2 11.7 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase CIAPIN1 PF05093.13 KFP02681.1 - 1.7e-22 79.8 16.7 4.6e-17 62.4 4.3 2.6 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Methyltransf_11 PF08241.12 KFP02681.1 - 1.4e-05 25.7 0.0 2.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP02681.1 - 3.1e-05 23.8 0.0 6.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP02681.1 - 0.0078 16.9 0.0 0.015 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP02681.1 - 0.048 14.4 0.0 0.097 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KFP02681.1 - 0.065 13.1 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 KFP02681.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Tat PF00539.18 KFP02681.1 - 8.8 6.6 13.3 0.11 12.7 1.7 2.3 1 1 1 2 2 2 0 Transactivating regulatory protein (Tat) COQ9 PF08511.11 KFP02682.1 - 3.5e-36 122.8 0.3 6.8e-36 121.9 0.3 1.5 1 0 0 1 1 1 1 COQ9 RNA_pol_A_bac PF01000.26 KFP02683.1 - 2.6e-40 137.3 0.0 3.6e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KFP02683.1 - 4e-12 45.4 0.0 5.6e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain IRS PF02174.17 KFP02684.1 - 6.9e-30 102.9 0.0 1.2e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.29 KFP02684.1 - 3.5e-06 27.5 0.3 6.4e-06 26.6 0.3 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFP02684.1 - 0.0075 16.7 1.5 0.055 13.9 1.5 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain RGM_C PF06534.13 KFP02684.1 - 0.023 14.2 0.4 0.04 13.4 0.4 1.3 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) C-terminus Furin-like PF00757.20 KFP02684.1 - 0.04 13.8 1.7 0.08 12.8 1.7 1.4 1 0 0 1 1 1 0 Furin-like cysteine rich region Myosin_tail_1 PF01576.19 KFP02685.1 - 6.8e-08 30.8 41.4 6.8e-08 30.8 41.4 3.2 2 1 1 3 3 3 2 Myosin tail Filament PF00038.21 KFP02685.1 - 0.015 14.9 64.2 0.052 13.1 1.4 3.9 1 1 2 3 3 3 0 Intermediate filament protein CRISPR_Cas2 PF09827.9 KFP02685.1 - 0.069 13.3 2.6 0.15 12.2 0.4 2.8 2 0 0 2 2 2 0 CRISPR associated protein Cas2 Fungal_TACC PF12709.7 KFP02685.1 - 0.15 12.5 0.1 0.15 12.5 0.1 6.3 3 1 1 6 6 6 0 Fungal Transforming acidic coiled-coil (TACC) proteins NPV_P10 PF05531.12 KFP02685.1 - 0.19 12.2 21.8 0.11 12.9 1.1 5.5 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 KFP02685.1 - 0.87 8.4 69.2 0.025 13.5 23.3 3.8 2 1 2 4 4 4 0 Spc7 kinetochore protein DUF2163 PF09931.9 KFP02685.1 - 0.93 9.7 7.1 0.62 10.3 2.0 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2163) DUF3450 PF11932.8 KFP02685.1 - 1 8.6 53.4 0.042 13.2 0.8 4.7 2 1 3 5 5 5 0 Protein of unknown function (DUF3450) PLL PF18587.1 KFP02686.1 - 3e-51 173.1 0.6 6.7e-51 171.9 0.6 1.6 1 0 0 1 1 1 1 PTX/LNS-Like (PLL) domain 7tm_2 PF00002.24 KFP02686.1 - 6.4e-30 104.2 18.9 9e-30 103.7 18.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 KFP02686.1 - 3.4e-12 46.7 6.8 3.4e-12 46.7 6.8 2.0 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif Zona_pellucida PF00100.23 KFP02687.1 - 6.8e-47 160.4 0.3 8.3e-47 160.1 0.3 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain EGF PF00008.27 KFP02687.1 - 8.3e-08 32.4 8.6 2.4e-07 30.9 8.6 1.9 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 KFP02687.1 - 0.0012 19.3 4.9 0.0012 19.3 4.9 2.3 3 0 0 3 3 3 1 Human growth factor-like EGF EGF_2 PF07974.13 KFP02687.1 - 0.0015 18.8 9.3 0.0038 17.5 9.3 1.7 1 0 0 1 1 1 1 EGF-like domain cEGF PF12662.7 KFP02687.1 - 0.032 14.2 2.1 0.094 12.7 2.1 1.9 1 0 0 1 1 1 0 Complement Clr-like EGF-like EGF_3 PF12947.7 KFP02687.1 - 1.3 9.3 6.9 3.1 8.1 6.9 1.7 1 0 0 1 1 1 0 EGF domain Katanin_con80 PF13925.6 KFP02690.1 - 3.6e-51 173.4 3.2 2.6e-50 170.6 3.2 2.1 1 1 0 1 1 1 1 con80 domain of Katanin WD40 PF00400.32 KFP02690.1 - 5.3e-49 163.2 8.1 1.2e-11 44.9 0.2 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP02690.1 - 1.4e-19 70.2 0.0 2.8e-05 24.3 0.0 5.6 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP02690.1 - 3.4e-06 27.1 0.0 0.00074 19.4 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KFP02690.1 - 0.002 16.8 0.1 9.2 4.8 0.0 3.9 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFP02690.1 - 0.0034 16.4 0.0 0.43 9.5 0.0 3.1 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KFP02690.1 - 0.079 11.7 0.1 3.2 6.4 0.0 3.2 1 1 3 4 4 4 0 Nup133 N terminal like cNMP_binding PF00027.29 KFP02691.1 - 1.4e-18 66.7 0.0 2.4e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain zf-C2H2 PF00096.26 KFP02692.1 - 2.5e-57 188.3 150.3 2.6e-06 27.6 0.9 17.2 17 0 0 17 17 17 15 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP02692.1 - 2.2e-53 176.4 140.7 1.6e-10 40.9 1.3 17.4 18 0 0 18 18 18 13 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP02692.1 - 9.4e-39 128.7 135.8 0.0013 19.4 2.1 17.1 17 0 0 17 17 17 15 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP02692.1 - 2.1e-24 85.2 86.5 0.00089 19.5 0.3 15.0 15 0 0 15 15 15 10 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP02692.1 - 5.8e-15 55.1 97.3 0.015 15.7 0.7 14.9 15 0 0 15 15 14 9 Zinc-finger of C2H2 type BolA PF01722.18 KFP02692.1 - 2.4e-06 27.7 35.4 0.34 11.2 0.3 8.8 3 2 5 10 10 10 4 BolA-like protein zf-C2H2_6 PF13912.6 KFP02692.1 - 2.8e-05 24.0 9.6 5.1e-05 23.2 1.6 17.2 17 1 0 17 17 17 8 C2H2-type zinc finger MRP-S23 PF10484.9 KFP02692.1 - 0.0088 16.3 0.3 75 3.6 0.0 5.1 3 2 1 5 5 5 0 Mitochondrial ribosomal protein S23 Antimicrobial_3 PF08025.11 KFP02692.1 - 0.18 11.8 1.0 39 4.3 0.1 4.0 3 0 0 3 3 3 0 Spider antimicrobial peptide UPF0728 PF15092.6 KFP02692.1 - 0.85 9.5 7.3 3.8 7.4 0.1 4.6 4 1 1 5 5 4 0 Uncharacterised protein family UPF0728 Ta0938 PF11494.8 KFP02692.1 - 3.1 8.1 19.3 9.2 6.6 2.0 6.9 2 2 6 8 8 8 0 Ta0938 HVSL PF09749.9 KFP02693.1 - 6.4e-62 209.1 0.0 7e-62 209.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein Peptidase_M10 PF00413.24 KFP02694.1 - 1.3e-58 197.3 0.0 1.9e-58 196.8 0.0 1.2 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 KFP02694.1 - 3.6e-41 138.9 18.6 1.8e-15 56.6 1.2 4.6 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 KFP02694.1 - 1.5e-09 37.9 0.1 2.9e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Reprolysin_3 PF13582.6 KFP02694.1 - 0.0021 18.6 0.1 0.004 17.7 0.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 KFP02694.1 - 0.015 15.0 0.6 1.3 8.6 0.1 2.2 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) DUF4953 PF16313.5 KFP02694.1 - 0.035 13.3 0.2 0.054 12.7 0.2 1.2 1 0 0 1 1 1 0 Met-zincin Metallopep PF12044.8 KFP02694.1 - 0.044 12.4 0.0 0.067 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_5 PF13688.6 KFP02694.1 - 0.049 13.8 0.0 0.072 13.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M54 PF07998.11 KFP02694.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 Peptidase_M66 PF10462.9 KFP02694.1 - 0.13 11.2 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 DUF667 PF05018.13 KFP02695.1 - 4.3e-76 254.8 0.7 4.8e-76 254.6 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) DUF667 PF05018.13 KFP02696.1 - 1.2e-77 259.8 0.4 1.3e-77 259.7 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Pkinase PF00069.25 KFP02698.1 - 9.6e-71 238.2 0.9 1.2e-70 238.0 0.9 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP02698.1 - 1.1e-20 74.0 0.2 2e-20 73.2 0.1 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFP02698.1 - 8.5e-10 38.9 0.0 1.7e-06 28.1 0.0 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFP02698.1 - 0.00089 18.1 0.1 0.0075 15.1 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KFP02698.1 - 0.0061 15.9 0.4 0.011 15.1 0.4 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFP02698.1 - 0.007 16.0 0.2 0.016 14.8 0.2 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 KFP02698.1 - 0.036 13.4 0.4 0.17 11.1 0.1 2.1 2 1 0 2 2 2 0 Kinase-like PAS_3 PF08447.12 KFP02698.1 - 0.086 13.1 0.1 0.26 11.6 0.1 1.8 1 0 0 1 1 1 0 PAS fold ABC1 PF03109.16 KFP02698.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 ABC1 family DUF4201 PF13870.6 KFP02699.1 - 3.4e-33 114.8 21.9 3.4e-33 114.8 21.9 2.2 1 1 0 2 2 2 2 Domain of unknown function (DUF4201) DUF948 PF06103.11 KFP02699.1 - 0.051 13.8 0.3 0.051 13.8 0.3 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4980 PF16352.5 KFP02699.1 - 0.083 12.9 1.0 0.2 11.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4980) GAS PF13851.6 KFP02699.1 - 1.7 7.9 30.8 0.41 10.0 1.8 3.2 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 KFP02699.1 - 3.8 7.6 16.6 0.75 9.8 0.7 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) HIP1_clath_bdg PF16515.5 KFP02699.1 - 5.8 7.6 33.7 0.23 12.1 1.1 4.1 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Sld5 PF05916.11 KFP02700.1 - 1.3e-09 38.5 0.0 1.6e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein I-set PF07679.16 KFP02701.1 - 3.9e-42 142.2 0.0 1.9e-12 47.1 0.1 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP02701.1 - 3.4e-38 130.1 0.0 1.4e-12 48.0 0.1 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFP02701.1 - 1.7e-27 95.6 1.5 8.8e-10 38.8 0.0 4.2 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 KFP02701.1 - 4.9e-20 71.5 0.0 7.3e-07 29.3 0.1 3.7 3 0 0 3 3 3 3 Immunoglobulin domain Ig_4 PF16680.5 KFP02701.1 - 1.7e-09 37.8 0.0 0.0017 18.6 0.0 3.5 3 0 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFP02701.1 - 1.2e-08 34.9 0.5 0.11 12.6 0.0 4.2 3 2 1 4 4 4 3 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFP02701.1 - 2.3e-07 30.9 0.4 0.0011 19.2 0.0 4.7 3 3 2 5 5 5 1 Immunoglobulin V-set domain TSP_1 PF00090.19 KFP02701.1 - 1.3e-06 28.6 46.8 4.7e-06 26.7 10.1 4.9 4 1 0 4 4 4 3 Thrombospondin type 1 domain Ig_C17orf99 PF17736.1 KFP02701.1 - 0.00086 19.3 0.0 4.2 7.5 0.0 3.4 3 0 0 3 3 3 2 C17orf99 Ig domain TSP_1 PF00090.19 KFP02702.1 - 2.6e-21 75.6 75.6 1.2e-05 25.4 3.9 7.9 7 2 0 7 7 7 6 Thrombospondin type 1 domain ADAM_spacer1 PF05986.14 KFP02702.1 - 0.0077 16.3 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 BAR PF03114.18 KFP02704.1 - 1.6e-74 250.6 7.2 1.8e-74 250.4 7.2 1.0 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KFP02704.1 - 3.2e-15 55.5 0.3 1.7e-14 53.2 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFP02704.1 - 1.2e-13 50.6 0.0 2.2e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFP02704.1 - 1.5e-13 50.4 0.1 2.9e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.9 KFP02704.1 - 4.1e-08 32.7 4.1 1.4e-07 30.9 2.6 1.9 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 KFP02704.1 - 5e-05 23.1 4.6 0.00074 19.3 4.6 2.2 1 1 0 1 1 1 1 BAR domain of APPL family MRF_C1 PF13887.6 KFP02704.1 - 0.032 13.4 0.1 0.18 11.0 0.1 2.1 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 DNA_pol_B_2 PF03175.13 KFP02704.1 - 0.11 11.4 0.9 0.15 10.9 0.9 1.1 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Exonuc_VII_L PF02601.15 KFP02704.1 - 1.7 8.1 5.1 2.5 7.6 5.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit BRE1 PF08647.11 KFP02705.1 - 0.0053 16.8 14.6 0.0053 16.8 14.6 3.4 1 1 1 3 3 3 1 BRE1 E3 ubiquitin ligase PGA_cap PF09587.10 KFP02705.1 - 0.01 15.3 0.3 0.022 14.2 0.1 1.7 1 1 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Fib_alpha PF08702.10 KFP02705.1 - 0.16 12.2 25.9 0.044 14.0 10.6 3.0 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KFP02705.1 - 0.68 10.0 18.9 0.53 10.3 5.7 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 KFP02705.1 - 1.1 9.5 9.4 8.4 6.7 2.4 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Frataxin_Cyay PF01491.16 KFP02705.1 - 2.4 8.3 8.4 0.17 12.0 0.8 2.9 1 1 0 2 2 2 0 Frataxin-like domain COG2 PF06148.11 KFP02705.1 - 4.4 7.4 20.4 0.26 11.3 4.1 2.9 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2316 PF10078.9 KFP02705.1 - 6 7.2 16.2 5.4 7.3 2.4 3.9 1 1 3 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2316) zf-C2H2 PF00096.26 KFP02706.1 - 6.9e-11 42.0 32.8 0.0037 17.6 1.8 7.2 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-met PF12874.7 KFP02706.1 - 5.2e-08 33.0 18.9 0.0045 17.3 0.1 5.6 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFP02706.1 - 2.6e-07 30.9 35.8 0.0067 17.2 1.1 7.5 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP02706.1 - 8.8e-06 25.9 14.7 0.092 13.1 0.6 4.9 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 KFP02706.1 - 0.049 13.8 10.1 0.22 11.7 0.3 3.7 3 0 0 3 3 3 0 Aberrant zinc-finger DUF5472 PF17566.2 KFP02706.1 - 0.92 9.5 6.0 37 4.4 0.1 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5472) DMSP_lyase PF16867.5 KFP02707.1 - 3 7.5 7.9 26 4.4 1.8 3.7 2 1 0 2 2 2 0 Dimethlysulfonioproprionate lyase LEDGF PF11467.8 KFP02708.1 - 4.7e-28 97.2 5.6 4.7e-28 97.2 5.6 2.4 3 0 0 3 3 3 1 Lens epithelium-derived growth factor (LEDGF) PWWP PF00855.17 KFP02708.1 - 2.1e-08 34.5 0.1 2.1e-08 34.5 0.1 4.3 4 2 0 4 4 4 1 PWWP domain zf-SNAP50_C PF12251.8 KFP02709.1 - 7.4e-76 254.3 3.0 9.4e-76 253.9 3.0 1.1 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal DUF3808 PF10300.9 KFP02710.1 - 5.5e-167 556.3 9.7 6.8e-167 556.0 9.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_12 PF13424.6 KFP02710.1 - 2.1e-10 40.7 1.5 0.00016 21.9 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFP02710.1 - 2.1e-06 27.3 4.8 0.11 12.3 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFP02710.1 - 3.2e-06 26.8 11.5 0.39 11.0 0.3 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFP02710.1 - 0.014 15.9 5.5 0.16 12.5 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP02710.1 - 0.014 15.4 1.5 1 9.5 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat B1 PF02246.15 KFP02710.1 - 0.046 13.8 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Protein L b1 domain TPR_6 PF13174.6 KFP02710.1 - 0.08 13.6 17.0 0.33 11.7 0.3 6.8 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFP02710.1 - 0.16 12.2 6.6 5.3 7.5 0.6 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DAN PF03045.15 KFP02711.1 - 6.5e-29 100.2 9.1 6.5e-29 100.2 9.1 1.7 2 0 0 2 2 2 1 DAN domain Cys_knot PF00007.22 KFP02711.1 - 0.00016 22.0 7.4 0.00024 21.3 7.4 1.3 1 0 0 1 1 1 1 Cystine-knot domain Sclerostin PF05463.11 KFP02711.1 - 0.00021 21.1 2.8 0.00065 19.5 2.8 1.8 1 1 0 1 1 1 1 Sclerostin (SOST) ET PF01684.16 KFP02711.1 - 0.19 12.1 3.0 0.3 11.5 2.7 1.5 1 1 0 1 1 1 0 ET module DUF1661 PF07877.11 KFP02711.1 - 0.27 11.0 0.2 0.27 11.0 0.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1661) DHHC PF01529.20 KFP02712.1 - 3.9e-34 117.6 11.0 3.9e-34 117.6 11.0 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase CTF_NFI PF00859.18 KFP02713.1 - 3.5e-111 371.8 24.8 4.7e-111 371.4 24.8 1.2 1 0 0 1 1 1 1 CTF/NF-I family transcription modulation region LURAP PF14854.6 KFP02714.1 - 1.8e-13 50.5 0.4 2.4e-13 50.1 0.4 1.2 1 0 0 1 1 1 1 Leucine rich adaptor protein LURAP PF14854.6 KFP02715.1 - 5e-39 132.9 2.2 6.2e-39 132.6 2.2 1.1 1 0 0 1 1 1 1 Leucine rich adaptor protein Tax PF02959.16 KFP02715.1 - 0.16 11.4 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 HTLV Tax Tyrosinase PF00264.20 KFP02716.1 - 4.8e-34 118.6 0.1 7.4e-34 118.0 0.1 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Laminin_EGF PF00053.24 KFP02716.1 - 0.61 10.3 13.4 2.1 8.5 9.8 3.0 2 1 0 2 2 2 0 Laminin EGF domain GDC-P PF02347.16 KFP02717.1 - 1.1e-167 558.2 0.0 3.3e-156 520.4 0.0 3.0 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KFP02717.1 - 7.4e-09 35.3 0.0 1.9e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KFP02717.1 - 1.1e-05 24.6 0.1 0.00014 20.9 0.1 2.3 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KFP02717.1 - 0.016 14.4 0.0 0.05 12.8 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class I and II Pyridoxal_deC PF00282.19 KFP02717.1 - 0.021 13.6 0.2 1.2 7.8 0.1 2.2 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain TTD PF12148.8 KFP02718.1 - 1.7e-67 226.2 0.6 3.3e-67 225.2 0.6 1.5 1 0 0 1 1 1 1 Tandem tudor domain within UHRF1 SAD_SRA PF02182.17 KFP02718.1 - 4.6e-53 179.1 1.7 5.8e-53 178.8 0.0 2.0 2 1 0 2 2 2 1 SAD/SRA domain PHD PF00628.29 KFP02718.1 - 1.2e-09 37.9 11.3 1.2e-09 37.9 11.3 3.5 2 2 1 3 3 2 1 PHD-finger zf-C3HC4_2 PF13923.6 KFP02718.1 - 2.4e-05 24.0 13.4 2.4e-05 24.0 13.4 3.0 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP02718.1 - 0.0001 22.1 10.6 0.0001 22.1 10.6 4.2 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP02718.1 - 0.0002 21.3 9.4 0.0002 21.3 9.4 3.6 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFP02718.1 - 0.00034 20.4 13.4 0.00034 20.4 13.4 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP02718.1 - 0.0013 18.7 9.9 0.0052 16.8 9.9 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_10 PF16685.5 KFP02718.1 - 0.0017 18.4 7.1 0.0017 18.4 7.1 3.1 2 1 0 2 2 2 1 zinc RING finger of MSL2 PHD_2 PF13831.6 KFP02718.1 - 0.0074 15.8 1.4 0.0074 15.8 1.4 3.6 3 0 0 3 3 3 1 PHD-finger Prok-RING_4 PF14447.6 KFP02718.1 - 0.013 15.4 8.5 0.013 15.4 8.5 3.5 2 1 0 2 2 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KFP02718.1 - 0.022 15.1 12.9 0.022 15.1 12.9 3.0 2 1 0 2 2 2 0 Ring finger domain ubiquitin PF00240.23 KFP02718.1 - 0.16 11.8 0.3 0.45 10.3 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin family Peptidase_C62 PF12380.8 KFP02719.1 - 0.047 12.8 0.1 0.055 12.6 0.1 1.1 1 0 0 1 1 1 0 Gill-associated viral 3C-like peptidase MOZ_SAS PF01853.18 KFP02719.1 - 0.091 12.4 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 MOZ/SAS family MCU PF04678.13 KFP02720.1 - 1.7 8.7 5.1 3 7.9 0.4 2.3 2 0 0 2 2 2 0 Mitochondrial calcium uniporter MLANA PF14991.6 KFP02722.1 - 1.1e-37 128.9 0.0 1.2e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 Protein melan-A WBP-1 PF11669.8 KFP02722.1 - 0.0052 17.4 0.0 0.0069 17.0 0.0 1.1 1 0 0 1 1 1 1 WW domain-binding protein 1 TMEM190 PF15431.6 KFP02722.1 - 0.19 11.9 0.0 0.21 11.7 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 190 RmuC PF02646.16 KFP02722.1 - 0.27 10.4 0.1 0.27 10.3 0.1 1.1 1 0 0 1 1 1 0 RmuC family SKG6 PF08693.10 KFP02722.1 - 0.39 10.2 2.8 0.73 9.3 2.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Peptidase_M28 PF04389.17 KFP02723.1 - 2.8e-48 164.2 0.0 3.9e-48 163.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KFP02723.1 - 0.00018 21.3 0.0 0.0006 19.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KFP02723.1 - 0.18 10.8 0.0 0.33 9.9 0.0 1.3 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase Adeno_GP19K PF04881.13 KFP02723.1 - 8.1 6.4 6.3 1.8 8.6 0.7 2.2 2 0 0 2 2 2 0 Adenovirus GP19K Ig_3 PF13927.6 KFP02724.1 - 2.1e-09 37.9 0.1 0.00072 20.1 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP02724.1 - 4.6e-08 33.0 0.1 0.0082 16.2 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 KFP02724.1 - 1.8e-07 31.3 0.2 6.9e-07 29.4 0.0 1.9 1 1 1 2 2 2 1 Immunoglobulin V-set domain ig PF00047.25 KFP02724.1 - 3.2e-06 27.2 0.4 0.011 15.8 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFP02724.1 - 0.0018 18.3 0.1 0.0077 16.3 0.0 2.0 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFP02724.1 - 0.01 16.2 0.3 0.027 14.8 0.1 1.9 2 0 0 2 2 2 0 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFP02724.1 - 0.026 14.1 0.0 0.7 9.5 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin domain MBF2 PF15868.5 KFP02724.1 - 0.041 14.4 0.1 0.32 11.5 0.1 2.2 2 0 0 2 2 2 0 Transcription activator MBF2 Ig_3 PF13927.6 KFP02725.1 - 5.4e-13 49.4 0.3 8.1e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFP02725.1 - 4.8e-12 46.0 0.0 1e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFP02725.1 - 2e-09 37.4 0.2 9.2e-06 25.6 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP02725.1 - 1.3e-07 31.8 1.0 0.0047 17.2 0.0 2.8 1 1 1 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP02725.1 - 1.4e-06 28.4 2.7 0.00029 20.9 0.1 3.1 2 2 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFP02725.1 - 0.00018 21.5 0.1 0.006 16.6 0.1 2.2 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFP02725.1 - 0.0032 17.0 0.0 0.0072 15.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFP02725.1 - 0.023 14.7 0.0 0.26 11.4 0.0 2.4 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain C1-set PF07654.15 KFP02725.1 - 0.1 13.0 0.7 0.41 11.1 0.2 2.1 2 0 0 2 2 2 0 Immunoglobulin C1-set domain DUF2368 PF10166.9 KFP02726.1 - 3.3e-37 127.1 0.2 3.6e-37 127.0 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2368) Insulin PF00049.18 KFP02727.1 - 0.011 16.8 0.0 0.013 16.5 0.0 1.2 1 0 0 1 1 1 0 Insulin/IGF/Relaxin family HIF-1 PF11413.8 KFP02727.1 - 0.16 11.4 0.5 0.28 10.6 0.5 1.4 1 0 0 1 1 1 0 Hypoxia-inducible factor-1 Pkinase_Tyr PF07714.17 KFP02728.1 - 2.4e-146 485.8 0.0 1.1e-85 287.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFP02728.1 - 6.5e-75 251.9 0.0 3.9e-51 173.9 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain FERM_F2 PF18377.1 KFP02728.1 - 1.1e-43 148.3 0.2 2.8e-43 147.0 0.2 1.8 1 0 0 1 1 1 1 FERM F2 acyl-CoA binding protein-like domain FERM_F1 PF18379.1 KFP02728.1 - 5e-40 135.4 0.7 5e-40 135.4 0.7 2.2 3 0 0 3 3 3 1 FERM F1 ubiquitin-like domain Jak1_Phl PF17887.1 KFP02728.1 - 3.3e-20 72.5 1.4 1.4e-18 67.3 0.2 2.4 1 1 1 2 2 2 1 Jak1 pleckstrin homology-like domain Kdo PF06293.14 KFP02728.1 - 2.8e-06 26.9 0.7 0.014 14.7 0.2 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFP02728.1 - 6.5e-05 22.4 0.0 0.0076 15.6 0.0 2.8 2 1 0 2 2 2 1 Kinase-like FERM_M PF00373.18 KFP02728.1 - 0.00063 20.1 0.1 0.0018 18.7 0.1 1.8 1 0 0 1 1 1 1 FERM central domain RIO1 PF01163.22 KFP02728.1 - 0.0014 18.3 1.1 0.23 11.0 0.1 2.5 2 0 0 2 2 2 2 RIO1 family APH PF01636.23 KFP02728.1 - 0.019 14.9 0.0 1 9.2 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family RTC PF01137.21 KFP02730.1 - 2.2e-42 144.8 0.0 2.5e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KFP02730.1 - 1.3e-36 125.2 0.0 2.1e-36 124.6 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain SDF PF00375.18 KFP02731.1 - 2.5e-133 444.9 25.5 2.8e-133 444.7 25.5 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF5083 PF16890.5 KFP02731.1 - 5.4 6.7 6.9 0.44 10.3 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5083) DUF3021 PF11457.8 KFP02731.1 - 9.8 6.5 20.3 0.51 10.7 7.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3021) Sad1_UNC PF07738.13 KFP02733.1 - 1.6e-33 115.5 0.0 1.8e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF5000 PF16391.5 KFP02733.1 - 0.026 14.6 0.0 0.61 10.2 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function ADK PF00406.22 KFP02734.1 - 1e-51 175.0 0.0 1.2e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KFP02734.1 - 3.5e-21 76.0 0.0 6.9e-21 75.1 0.0 1.5 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 KFP02734.1 - 5.3e-17 61.5 0.0 1.2e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KFP02734.1 - 1.5e-06 28.8 0.0 2.5e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFP02734.1 - 8.8e-05 22.7 0.0 0.00039 20.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KFP02734.1 - 0.0028 17.4 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase RNA_helicase PF00910.22 KFP02734.1 - 0.19 12.1 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase CDC37_M PF08565.11 KFP02735.1 - 5e-19 68.4 0.1 1e-18 67.4 0.1 1.5 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain Ribosomal_S8e PF01201.22 KFP02737.1 - 1.6e-47 161.1 1.2 2.4e-47 160.6 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e GTP_EFTU PF00009.27 KFP02738.1 - 9.7e-68 227.5 0.0 1.5e-67 226.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KFP02738.1 - 1.2e-28 99.0 0.0 5.6e-28 96.9 0.0 2.3 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 KFP02738.1 - 2.9e-23 81.7 0.0 6.8e-23 80.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 KFP02738.1 - 8.1e-12 45.0 0.0 2.5e-11 43.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 KFP02738.1 - 2.4e-08 34.2 0.0 5.4e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KFP02738.1 - 2.6e-08 33.8 0.0 3.1e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 KFP02738.1 - 6.9e-05 22.9 0.0 0.00015 21.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFP02738.1 - 0.018 14.6 0.0 0.095 12.2 0.0 2.1 2 1 0 2 2 2 0 Ferrous iron transport protein B AIG1 PF04548.16 KFP02738.1 - 0.066 12.5 0.0 0.16 11.2 0.0 1.6 1 0 0 1 1 1 0 AIG1 family AvrPtoB_bdg PF16847.5 KFP02738.1 - 0.073 13.6 0.0 1.2 9.6 0.0 2.9 3 0 0 3 3 3 0 Avirulence AvrPtoB, BAK1-binding domain Glyco_hydro_20 PF00728.22 KFP02739.1 - 2.5e-82 277.1 0.0 3.6e-82 276.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KFP02739.1 - 9.1e-05 23.1 0.0 0.00017 22.3 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Kelch_1 PF01344.25 KFP02741.1 - 6.8e-50 166.4 7.6 1.5e-11 43.6 0.0 5.6 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 KFP02741.1 - 1.3e-30 105.5 2.2 3.9e-30 104.0 1.5 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 KFP02741.1 - 4.1e-29 101.0 0.2 8.2e-29 100.1 0.2 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.6 KFP02741.1 - 6.3e-24 83.4 5.6 2.3e-05 24.5 0.0 5.9 2 1 4 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KFP02741.1 - 3.6e-21 74.2 2.6 0.00017 21.4 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 KFP02741.1 - 6.6e-20 70.9 0.8 3e-07 30.3 0.0 5.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP02741.1 - 1.4e-19 69.8 4.3 5.1e-05 23.4 0.0 6.1 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP02741.1 - 1.5e-13 50.4 6.5 8.5e-07 28.8 0.0 5.2 6 0 0 6 6 6 3 Kelch motif DUF3342 PF11822.8 KFP02741.1 - 0.00027 21.1 0.4 0.0017 18.5 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3342) PFU PF09070.11 KFP02741.1 - 0.027 14.7 0.0 0.073 13.3 0.0 1.8 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) UTP15_C PF09384.10 KFP02742.1 - 2.8e-47 160.1 0.1 4.3e-47 159.5 0.1 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KFP02742.1 - 9.5e-24 83.2 7.1 7.1e-06 26.7 0.1 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP02742.1 - 1.3e-11 44.6 0.0 0.00024 21.3 0.1 4.4 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KFP02742.1 - 6.8e-05 22.9 0.0 0.067 13.2 0.0 3.3 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Ank_2 PF12796.7 KFP02743.1 - 3.9e-25 88.3 0.0 9e-13 48.6 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP02743.1 - 7.4e-22 77.1 0.2 2.2e-08 34.2 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP02743.1 - 4.2e-19 66.6 0.0 5.1e-06 26.4 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KFP02743.1 - 6.1e-19 67.6 0.0 6.5e-06 26.3 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KFP02743.1 - 3.1e-18 65.9 0.2 2.6e-07 31.1 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DUF1296 PF06972.11 KFP02743.1 - 0.23 11.7 0.8 2.8 8.1 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1296) NAC PF01849.18 KFP02744.1 - 1.9e-26 91.8 0.2 2.9e-26 91.2 0.2 1.3 1 0 0 1 1 1 1 NAC domain LolA PF03548.15 KFP02744.1 - 0.037 13.7 0.4 0.046 13.4 0.4 1.1 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA Myco_19_kDa PF05481.12 KFP02744.1 - 0.045 14.0 0.1 0.055 13.8 0.1 1.2 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen TMEM174 PF15029.6 KFP02745.1 - 1.3e-108 362.2 0.0 1.5e-108 362.0 0.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 174 TMEM171 PF15471.6 KFP02746.1 - 2.4e-151 503.2 1.4 2.8e-151 503.0 1.4 1.0 1 0 0 1 1 1 1 Transmembrane protein family 171 Phage_holin_3_6 PF07332.11 KFP02746.1 - 0.0089 16.1 2.1 0.3 11.1 0.2 2.3 2 1 0 2 2 2 1 Putative Actinobacterial Holin-X, holin superfamily III Tetraspanin PF00335.20 KFP02746.1 - 0.064 13.0 6.3 0.17 11.5 0.1 2.3 2 0 0 2 2 2 0 Tetraspanin family DUF2371 PF10177.9 KFP02746.1 - 0.12 12.6 0.2 1.4 9.1 0.1 2.4 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) TMEM174 PF15029.6 KFP02746.1 - 0.12 12.1 7.1 0.55 9.9 3.3 3.0 2 1 0 2 2 2 0 Transmembrane protein 174 Sec61_beta PF03911.16 KFP02747.1 - 1.1e-19 70.2 0.0 1.4e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Sec61beta family zf-C4 PF00105.18 KFP02748.1 - 3.6e-31 107.4 18.3 6.4e-31 106.6 18.3 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFP02748.1 - 2.2e-19 69.9 0.0 3.8e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor SNARE PF05739.19 KFP02749.1 - 1.9e-06 27.7 0.2 3.7e-06 26.8 0.2 1.5 1 0 0 1 1 1 1 SNARE domain Red1 PF07964.11 KFP02749.1 - 0.0042 15.4 1.2 0.0076 14.5 1.2 1.3 1 0 0 1 1 1 1 Rec10 / Red1 Phage_holin_3_6 PF07332.11 KFP02749.1 - 0.0099 15.9 0.3 0.023 14.8 0.3 1.6 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III Vac_Fusion PF02346.16 KFP02749.1 - 0.044 13.4 0.9 0.1 12.2 0.1 2.1 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 SlyX PF04102.12 KFP02749.1 - 0.045 14.4 0.2 0.045 14.4 0.2 2.7 3 0 0 3 3 3 0 SlyX RseC_MucC PF04246.12 KFP02749.1 - 0.064 13.2 0.0 0.095 12.7 0.0 1.3 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC ThrE PF06738.12 KFP02749.1 - 0.099 12.0 0.3 0.28 10.5 0.0 1.7 2 0 0 2 2 2 0 Putative threonine/serine exporter GrpE PF01025.19 KFP02749.1 - 2.9 7.5 6.2 0.84 9.3 1.0 2.2 2 0 0 2 2 2 0 GrpE Gly-zipper_Omp PF13488.6 KFP02749.1 - 4.8 7.3 17.7 13 5.9 17.7 1.6 1 1 0 1 1 1 0 Glycine zipper Thioredoxin_6 PF13848.6 KFP02750.1 - 9.3e-46 156.0 0.1 1.3e-41 142.5 0.1 2.4 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 KFP02750.1 - 3.3e-21 75.2 0.0 8.4e-21 73.9 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Calsequestrin PF01216.17 KFP02750.1 - 1.2e-07 31.1 0.2 2.6e-07 30.0 0.1 1.5 2 0 0 2 2 2 1 Calsequestrin OST3_OST6 PF04756.13 KFP02750.1 - 2.5e-05 23.8 0.0 4.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KFP02750.1 - 0.00043 20.7 0.1 0.0018 18.7 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain HyaE PF07449.11 KFP02750.1 - 0.00065 19.6 0.0 0.0021 18.0 0.0 1.8 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 KFP02750.1 - 0.0063 16.8 0.2 0.091 13.1 0.1 2.5 1 1 1 2 2 2 1 Thioredoxin-like Ank_2 PF12796.7 KFP02751.1 - 1.7e-88 291.3 17.7 1.1e-16 61.2 0.0 8.2 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP02751.1 - 1.3e-69 229.7 18.8 9.7e-11 42.0 0.1 11.3 5 2 8 13 13 13 11 Ankyrin repeats (many copies) Ank PF00023.30 KFP02751.1 - 2.2e-63 208.1 24.0 3.9e-05 23.9 0.1 15.8 16 0 0 16 16 16 14 Ankyrin repeat Ank_3 PF13606.6 KFP02751.1 - 6.9e-63 201.2 18.5 0.00043 20.5 0.0 15.8 16 0 0 16 16 16 13 Ankyrin repeat Ank_5 PF13857.6 KFP02751.1 - 1.8e-61 203.3 22.3 1.1e-09 38.3 0.1 11.9 5 4 7 12 12 12 12 Ankyrin repeats (many copies) IQ PF00612.27 KFP02751.1 - 6e-08 31.8 7.8 0.0026 17.4 0.9 2.9 2 0 0 2 2 2 2 IQ calmodulin-binding motif Ipi1_N PF12333.8 KFP02752.1 - 3.6e-23 82.1 0.8 3.6e-23 82.1 0.8 3.7 4 0 0 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation Vac14_Fab1_bd PF12755.7 KFP02752.1 - 0.016 15.8 0.1 0.16 12.6 0.0 2.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 KFP02752.1 - 0.033 14.6 0.0 0.25 11.7 0.0 2.5 2 0 0 2 2 2 0 HEAT repeats HEAT_EZ PF13513.6 KFP02752.1 - 0.034 14.7 1.6 0.33 11.5 0.0 3.4 4 0 0 4 4 4 0 HEAT-like repeat DUF2474 PF10617.9 KFP02752.1 - 4.4 7.2 6.8 3.3 7.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2474) Myb_DNA-bind_5 PF13873.6 KFP02753.1 - 5e-23 81.0 2.1 5e-23 81.0 2.1 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KFP02753.1 - 0.0067 16.7 2.6 0.0067 16.7 2.6 2.5 2 1 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Macro PF01661.21 KFP02753.1 - 0.11 12.6 0.0 0.45 10.6 0.0 1.9 1 1 0 1 1 1 0 Macro domain RecU PF03838.14 KFP02753.1 - 0.42 10.6 6.4 0.17 11.9 1.8 2.2 2 1 0 2 2 2 0 Recombination protein U EF-hand_7 PF13499.6 KFP02754.1 - 7.8e-25 87.1 2.1 2.1e-11 44.1 0.7 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KFP02754.1 - 6.7e-24 81.6 9.9 3.1e-07 29.5 0.1 5.3 5 1 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 KFP02754.1 - 2.2e-22 77.0 5.3 4.3e-07 29.3 0.1 5.2 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.6 KFP02754.1 - 1.4e-20 72.8 4.5 9.5e-07 28.6 0.2 4.9 2 2 3 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.6 KFP02754.1 - 6.4e-12 44.4 9.8 0.00035 19.9 0.1 4.4 5 0 0 5 5 5 3 EF hand EF-hand_9 PF14658.6 KFP02754.1 - 0.0037 17.5 0.0 0.57 10.6 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain WWE PF02825.20 KFP02754.1 - 0.013 16.1 0.3 0.56 10.8 0.2 2.5 2 1 0 2 2 2 0 WWE domain EF-hand_2 PF09068.11 KFP02754.1 - 0.043 14.0 0.0 2.6 8.2 0.0 2.5 2 1 0 2 2 2 0 EF hand SPARC_Ca_bdg PF10591.9 KFP02754.1 - 0.13 12.6 0.5 3.1 8.2 0.1 2.7 1 1 2 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DHC_N1 PF08385.12 KFP02755.1 - 9.8e-58 196.1 5.3 1.1e-57 196.0 5.3 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 FerA PF08165.11 KFP02755.1 - 0.0041 17.0 1.2 0.59 10.1 0.0 3.2 2 1 0 2 2 2 1 FerA (NUC095) domain DCX PF03607.17 KFP02755.1 - 0.093 12.9 0.1 6.7 6.9 0.1 2.7 1 1 0 1 1 1 0 Doublecortin PTRF_SDPR PF15237.6 KFP02756.1 - 9.5e-91 303.8 21.2 1.3e-90 303.4 21.2 1.1 1 0 0 1 1 1 1 PTRF/SDPR family DUF1664 PF07889.12 KFP02756.1 - 0.0078 16.2 8.0 0.0078 16.2 8.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Vac_Fusion PF02346.16 KFP02756.1 - 0.11 12.1 2.8 1.5 8.5 0.2 2.8 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 ACOX PF01756.19 KFP02756.1 - 0.15 11.6 2.9 0.14 11.7 1.1 1.8 2 0 0 2 2 2 0 Acyl-CoA oxidase MCPsignal PF00015.21 KFP02756.1 - 0.58 9.9 12.5 0.37 10.6 4.2 2.5 2 2 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 KFP02756.1 - 2.3 8.5 6.1 15 6.0 6.1 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF3287 PF11690.8 KFP02756.1 - 2.8 7.7 10.1 0.11 12.2 0.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3287) Hormone_1 PF00103.20 KFP02756.1 - 9.3 5.9 8.4 3.7 7.2 1.3 2.8 2 1 1 3 3 3 0 Somatotropin hormone family Kazal_2 PF07648.15 KFP02757.1 - 1.1e-19 70.3 26.2 9e-12 44.9 6.2 3.6 3 0 0 3 3 3 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFP02757.1 - 9.3e-14 51.2 27.2 1.2e-07 31.6 9.5 3.5 2 1 1 3 3 3 2 Kazal-type serine protease inhibitor domain DUF3844 PF12955.7 KFP02757.1 - 0.0027 17.8 1.3 0.0027 17.8 1.3 3.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3844) EphA2_TM PF14575.6 KFP02757.1 - 0.012 16.5 0.3 0.037 14.9 0.3 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain GRA6 PF05084.13 KFP02757.1 - 0.092 12.7 0.4 0.21 11.6 0.0 1.7 2 0 0 2 2 2 0 Granule antigen protein (GRA6) EGF PF00008.27 KFP02757.1 - 3 8.3 35.2 0.096 13.0 6.9 4.4 3 1 0 3 3 3 0 EGF-like domain Zip PF02535.22 KFP02758.1 - 8.3e-06 25.3 19.6 2.9e-05 23.4 19.6 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter OAD_gamma PF04277.13 KFP02758.1 - 0.21 12.2 0.6 0.29 11.7 0.6 1.4 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain GCV_H PF01597.19 KFP02759.1 - 6.1e-08 32.6 0.0 1e-07 31.8 0.0 1.4 2 0 0 2 2 2 1 Glycine cleavage H-protein Vinculin PF01044.19 KFP02760.1 - 1.1e-52 179.5 19.7 7.7e-33 113.8 5.4 3.3 3 1 0 3 3 3 3 Vinculin family WXG100 PF06013.12 KFP02760.1 - 0.11 12.8 5.5 0.051 13.8 1.0 2.9 3 0 0 3 3 3 0 Proteins of 100 residues with WXG COG5 PF10392.9 KFP02760.1 - 0.26 11.5 10.3 0.084 13.1 3.1 3.7 3 2 1 4 4 4 0 Golgi transport complex subunit 5 WD40 PF00400.32 KFP02761.1 - 4.6e-38 128.5 26.1 0.00052 20.8 0.0 12.7 13 0 0 13 13 13 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP02761.1 - 4.4e-05 23.7 5.1 6.6 7.1 0.1 7.0 5 3 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain bHLH-MYC_N PF14215.6 KFP02761.1 - 0.027 14.7 0.1 0.1 12.8 0.1 2.0 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal eIF2A PF08662.11 KFP02761.1 - 0.12 12.2 5.2 5.9 6.7 0.1 3.5 4 1 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KFP02761.1 - 1.6 8.8 6.2 62 3.7 0.0 4.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat 7tm_3 PF00003.22 KFP02762.1 - 7e-59 199.4 12.1 9.6e-59 199.0 12.1 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR GBR2_CC PF18455.1 KFP02762.1 - 2.7e-26 91.4 3.3 5.1e-26 90.5 3.3 1.5 1 0 0 1 1 1 1 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain Cation_ATPase_C PF00689.21 KFP02762.1 - 0.0031 17.2 13.0 0.052 13.3 0.5 2.9 2 1 1 3 3 3 2 Cation transporting ATPase, C-terminus UPF0242 PF06785.11 KFP02762.1 - 0.021 14.9 0.1 0.039 14.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GWT1 PF06423.12 KFP02762.1 - 0.057 13.5 3.8 0.58 10.3 0.5 2.7 2 1 1 3 3 3 0 GWT1 HOOK PF05622.12 KFP02762.1 - 0.058 11.5 6.1 0.079 11.1 6.1 1.1 1 0 0 1 1 1 0 HOOK protein TMEM52 PF14979.6 KFP02762.1 - 0.61 10.0 3.4 0.59 10.0 0.4 2.3 3 0 0 3 3 3 0 Transmembrane 52 Lectin_N PF03954.14 KFP02762.1 - 1.2 8.9 5.1 0.47 10.2 2.3 1.8 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF1418 PF07214.12 KFP02762.1 - 1.9 8.4 6.5 13 5.7 0.1 3.3 3 2 1 4 4 4 0 Protein of unknown function (DUF1418) Kelch_1 PF01344.25 KFP02765.1 - 1.7e-41 139.5 9.6 7.6e-10 38.2 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KFP02765.1 - 1.7e-40 136.0 5.3 4.5e-07 29.9 0.0 6.1 5 1 1 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KFP02765.1 - 2.6e-36 123.4 9.6 1.9e-10 40.6 0.0 5.9 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP02765.1 - 7.2e-33 112.0 7.2 4.9e-06 26.4 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KFP02765.1 - 1.7e-32 111.0 13.2 2.1e-07 31.1 0.0 7.1 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP02765.1 - 6.1e-26 89.4 13.6 7.5e-06 25.7 0.1 6.8 5 2 1 6 6 6 6 Kelch motif YccF PF03733.13 KFP02766.1 - 1.3e-19 70.6 12.7 1.3e-19 70.6 12.7 5.9 6 1 1 7 7 7 2 Inner membrane component domain Na_Ca_ex PF01699.24 KFP02766.1 - 1.4e-18 67.3 29.0 5.6e-14 52.4 15.3 3.4 5 0 0 5 5 5 2 Sodium/calcium exchanger protein CytochromB561_N PF09786.9 KFP02767.1 - 2.7e-124 416.3 1.3 1e-122 411.1 1.3 2.1 1 1 0 1 1 1 1 Cytochrome B561, N terminal Propep_M14 PF02244.16 KFP02768.1 - 1.4e-20 73.4 1.0 2.2e-20 72.8 1.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Peptidase_M14 PF00246.24 KFP02768.1 - 7.6e-06 25.9 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase GATA PF00320.27 KFP02769.1 - 6.3e-10 38.5 4.1 1.2e-09 37.6 4.1 1.5 1 0 0 1 1 1 1 GATA zinc finger LIM PF00412.22 KFP02769.1 - 0.0009 19.4 1.1 0.0016 18.6 1.1 1.4 1 0 0 1 1 1 1 LIM domain FAM76 PF16046.5 KFP02769.1 - 0.01 15.2 3.4 0.015 14.7 3.4 1.2 1 0 0 1 1 1 0 FAM76 protein DUF4603 PF15376.6 KFP02769.1 - 0.035 11.5 1.7 0.041 11.3 1.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DZR PF12773.7 KFP02769.1 - 0.082 12.9 3.0 0.17 12.0 3.0 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.15 KFP02769.1 - 0.19 11.8 3.9 1.1 9.4 2.0 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DUF1178 PF06676.11 KFP02769.1 - 0.53 10.7 5.2 0.2 12.0 2.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) TORC_M PF12885.7 KFP02770.1 - 6.5e-33 113.9 15.2 1.7e-32 112.6 9.6 2.6 2 1 0 2 2 2 2 Transducer of regulated CREB activity middle domain PAH PF02671.21 KFP02771.1 - 1.7e-10 40.8 3.4 6e-06 26.3 0.2 3.5 3 0 0 3 3 3 2 Paired amphipathic helix repeat Myb_DNA-bind_6 PF13921.6 KFP02771.1 - 0.00047 20.3 0.1 0.019 15.2 0.0 3.3 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFP02771.1 - 0.0021 18.2 0.0 0.014 15.5 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Tubulin_3 PF14881.6 KFP02772.1 - 3.1e-24 85.6 0.0 4.6e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 KFP02772.1 - 3.9e-07 30.5 0.0 6.4e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain DAP3 PF10236.9 KFP02773.1 - 1.6e-90 303.4 0.0 1.9e-90 303.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_25 PF13481.6 KFP02773.1 - 0.0091 15.6 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KFP02773.1 - 0.0094 15.9 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 KFP02773.1 - 0.06 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KFP02773.1 - 0.079 13.3 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KFP02773.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 KFP02773.1 - 0.15 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KFP02773.1 - 0.15 12.3 0.0 0.39 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KFP02773.1 - 0.19 11.5 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein BAH PF01426.18 KFP02774.1 - 6.9e-22 77.6 0.1 4.1e-21 75.1 0.1 2.5 2 0 0 2 2 2 1 BAH domain AWS PF17907.1 KFP02774.1 - 1.9e-16 59.8 12.6 1.9e-16 59.8 12.6 2.1 3 0 0 3 3 3 1 AWS domain Bromodomain PF00439.25 KFP02774.1 - 3.5e-15 55.8 0.1 1.2e-14 54.1 0.0 2.0 2 0 0 2 2 2 1 Bromodomain SET PF00856.28 KFP02774.1 - 1.1e-08 35.7 0.7 5.4e-06 26.9 0.1 4.0 2 1 0 2 2 2 1 SET domain PHD PF00628.29 KFP02774.1 - 1.2e-05 25.1 13.4 1.2e-05 25.1 13.4 2.3 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KFP02774.1 - 0.098 12.2 9.8 0.22 11.1 9.8 1.7 1 0 0 1 1 1 0 PHD-finger RUN PF02759.19 KFP02775.1 - 2.4e-18 66.4 0.0 4e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 RUN domain SH3_1 PF00018.28 KFP02775.1 - 2.7e-09 36.5 0.0 8.6e-09 34.9 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFP02775.1 - 2.5e-08 33.5 0.1 8.8e-08 31.7 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KFP02775.1 - 2.7e-07 30.3 0.0 6.1e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 KFP02775.1 - 0.079 13.0 0.3 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 SH3 domain polyprenyl_synt PF00348.17 KFP02776.1 - 7.2e-78 261.2 0.0 8.9e-78 260.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Ion_trans PF00520.31 KFP02777.1 - 7.6e-24 84.3 13.0 1.3e-23 83.5 13.0 1.4 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KFP02777.1 - 1.9e-18 66.3 0.0 3.9e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KFP02777.1 - 4.7e-05 23.3 0.1 0.00016 21.5 0.0 1.9 2 0 0 2 2 2 1 Ion channel SCAMP PF04144.13 KFP02778.1 - 4e-68 229.1 18.7 4.7e-68 228.9 18.7 1.1 1 0 0 1 1 1 1 SCAMP family FluMu_N PF17891.1 KFP02778.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Mu-like prophage FluMu N-terminal domain CD20 PF04103.15 KFP02779.1 - 4.2e-18 65.9 10.7 4.8e-18 65.7 10.7 1.0 1 0 0 1 1 1 1 CD20-like family UPF0139 PF03669.13 KFP02779.1 - 0.82 9.6 3.7 0.93 9.4 0.5 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) Glyco_hydro_30 PF02055.16 KFP02780.1 - 1.3e-165 550.5 0.6 1.5e-165 550.3 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 KFP02780.1 - 9.2e-09 35.4 0.1 1.5e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 KFP02780.1 - 9.3e-08 31.6 0.2 1.4e-07 31.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 DUF229 PF02995.17 KFP02780.1 - 0.14 10.7 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Glyco_hydro_30 PF02055.16 KFP02781.1 - 3e-145 483.6 0.2 3.5e-145 483.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain DUF229 PF02995.17 KFP02781.1 - 0.064 11.8 0.0 0.11 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Glyco_hydro_30 PF02055.16 KFP02782.1 - 3.2e-32 111.9 0.1 3.9e-32 111.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30 PF02055.16 KFP02783.1 - 1.9e-81 273.7 0.0 2.2e-81 273.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 KFP02783.1 - 1.8e-07 30.7 0.0 2.2e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 TSP_C PF05735.12 KFP02784.1 - 6.4e-70 235.1 0.7 8.6e-70 234.7 0.7 1.2 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.18 KFP02784.1 - 1.2e-61 204.1 132.3 1.6e-14 53.3 10.1 9.6 7 2 1 8 8 8 7 Thrombospondin type 3 repeat COMP PF11598.8 KFP02784.1 - 2.8e-19 69.3 4.5 5e-19 68.5 4.5 1.5 1 0 0 1 1 1 1 Cartilage oligomeric matrix protein EGF_CA PF07645.15 KFP02784.1 - 1.3e-12 47.7 20.2 9.1e-08 32.2 1.3 5.7 5 0 0 5 5 5 2 Calcium-binding EGF domain cEGF PF12662.7 KFP02784.1 - 3e-07 30.2 33.8 0.0002 21.2 1.8 5.4 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF_3 PF12947.7 KFP02784.1 - 5.4e-06 26.5 6.0 5.4e-06 26.5 6.0 7.0 4 2 1 5 5 5 3 EGF domain Laminin_G_2 PF02210.24 KFP02784.1 - 0.0042 17.7 0.0 0.0074 16.9 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain EGF PF00008.27 KFP02784.1 - 0.0042 17.4 6.6 0.0042 17.4 6.6 5.2 4 0 0 4 4 4 2 EGF-like domain TMEM52 PF14979.6 KFP02785.1 - 0.0029 17.6 0.4 0.0034 17.3 0.4 1.2 1 0 0 1 1 1 1 Transmembrane 52 EphA2_TM PF14575.6 KFP02785.1 - 0.041 14.8 0.0 0.047 14.6 0.0 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LAT PF15234.6 KFP02785.1 - 0.042 13.6 0.1 0.042 13.6 0.1 1.1 1 0 0 1 1 1 0 Linker for activation of T-cells Herpes_gE PF02480.16 KFP02785.1 - 0.054 12.2 0.0 0.054 12.2 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Keratin_assoc PF09775.9 KFP02786.1 - 3.4e-46 156.1 0.3 3.7e-46 155.9 0.3 1.0 1 0 0 1 1 1 1 Keratinocyte-associated protein 2 MtN3_slv PF03083.16 KFP02787.1 - 1.1e-29 102.3 0.3 1.6e-29 101.8 0.3 1.2 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 KFP02787.1 - 0.0034 17.1 1.1 0.0071 16.1 0.1 2.1 2 0 0 2 2 2 1 PQ loop repeat DC_STAMP PF07782.13 KFP02788.1 - 6.3e-39 133.8 4.4 7.7e-39 133.5 4.4 1.1 1 0 0 1 1 1 1 DC-STAMP-like protein DC_STAMP PF07782.13 KFP02789.1 - 1.2e-53 181.8 0.0 2.6e-53 180.7 0.0 1.6 1 0 0 1 1 1 1 DC-STAMP-like protein PAPS_reduct PF01507.19 KFP02790.1 - 7.9e-31 107.4 0.0 3.5e-28 98.8 0.0 2.3 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family MoCF_biosynth PF00994.24 KFP02790.1 - 5.7e-14 52.0 0.0 9.8e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain PID PF00640.23 KFP02791.1 - 3.4e-32 111.4 0.0 4.6e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.24 KFP02791.1 - 3.3e-18 65.5 0.0 5.3e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 SH2 domain Delta_lysin PF05372.11 KFP02791.1 - 0.062 12.6 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Delta lysin family A_deamin PF02137.18 KFP02792.1 - 1.9e-112 375.9 0.0 2.7e-112 375.5 0.0 1.2 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain z-alpha PF02295.17 KFP02792.1 - 2.5e-38 129.9 0.0 1.2e-18 66.9 0.0 2.8 2 0 0 2 2 2 2 Adenosine deaminase z-alpha domain dsrm PF00035.26 KFP02792.1 - 7.9e-37 125.8 0.3 1.1e-12 48.4 0.0 3.9 3 0 0 3 3 3 3 Double-stranded RNA binding motif CAP_N PF01213.19 KFP02792.1 - 3.5e-06 26.7 0.9 3.5e-06 26.7 0.9 2.2 2 1 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal TrmB PF01978.19 KFP02792.1 - 0.00019 21.2 0.0 1 9.3 0.0 2.8 3 0 0 3 3 3 2 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 KFP02792.1 - 0.15 12.0 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 MarR family PRIMA1 PF16101.5 KFP02792.1 - 0.73 9.9 9.6 2.2 8.4 3.3 2.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 UQ_con PF00179.26 KFP02793.1 - 1.6e-10 40.8 0.0 6e-10 38.9 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFP02793.1 - 0.0035 17.1 0.0 0.011 15.4 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic E2 family B IL13 PF03487.13 KFP02793.1 - 0.015 15.0 0.0 1.5 8.6 0.0 2.7 2 1 1 3 3 3 0 Interleukin-13 NA37 PF04245.13 KFP02793.1 - 0.058 12.9 0.1 0.092 12.2 0.1 1.4 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein Josephin PF02099.17 KFP02793.1 - 0.1 12.7 0.0 0.15 12.2 0.0 1.4 1 1 0 1 1 1 0 Josephin DUF2408 PF10303.9 KFP02793.1 - 0.22 12.1 1.5 0.46 11.0 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KIAA1430 PF13879.6 KFP02793.1 - 0.56 11.0 3.3 0.9 10.3 0.3 2.6 2 1 1 3 3 3 0 KIAA1430 homologue PhoLip_ATPase_C PF16212.5 KFP02795.1 - 2.8e-86 289.3 22.5 2.8e-86 289.3 22.5 2.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFP02795.1 - 1.8e-22 78.8 7.3 4.8e-22 77.4 7.3 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KFP02795.1 - 1.2e-11 44.5 0.0 6.3e-11 42.2 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFP02795.1 - 3.3e-10 40.6 0.9 0.00093 19.5 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFP02795.1 - 4.7e-07 29.5 0.1 2.1e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFP02795.1 - 0.00057 19.7 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Formyl_trans_C PF02911.18 KFP02795.1 - 0.18 12.0 0.0 0.76 10.1 0.0 2.1 2 0 0 2 2 2 0 Formyl transferase, C-terminal domain DUF3899 PF13038.6 KFP02795.1 - 4.4 7.9 9.1 0.21 12.1 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) MIP PF00230.20 KFP02796.1 - 1.9e-38 132.4 7.0 2.2e-38 132.2 7.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein NICE-3 PF07406.11 KFP02798.1 - 1.1e-39 136.3 0.2 1.7e-39 135.7 0.1 1.3 2 0 0 2 2 2 1 NICE-3 protein Tropomyosin PF00261.20 KFP02799.1 - 1.6e-70 237.1 72.2 4.9e-65 219.2 45.7 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 KFP02799.1 - 2.7e-34 118.4 61.0 3.6e-34 118.0 44.5 2.2 1 1 1 2 2 2 1 Tropomyosin like CLZ PF16526.5 KFP02799.1 - 8.7e-07 29.2 41.3 2.1e-06 28.0 12.4 4.0 2 2 2 4 4 4 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Laminin_II PF06009.12 KFP02799.1 - 0.00017 21.6 26.7 0.03 14.4 11.5 3.0 1 1 2 3 3 3 2 Laminin Domain II XhlA PF10779.9 KFP02799.1 - 0.0013 18.9 3.3 0.0013 18.9 3.3 4.8 1 1 4 5 5 5 3 Haemolysin XhlA ATG16 PF08614.11 KFP02799.1 - 0.0056 16.9 23.5 0.0056 16.9 23.5 2.6 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) ERM PF00769.19 KFP02799.1 - 0.0075 16.1 59.0 0.051 13.4 43.1 2.2 1 1 0 2 2 2 2 Ezrin/radixin/moesin family HrpB7 PF09486.10 KFP02799.1 - 0.0087 16.5 17.9 0.0087 16.5 17.9 3.2 1 1 1 3 3 3 3 Bacterial type III secretion protein (HrpB7) DHR10 PF18595.1 KFP02799.1 - 0.017 15.2 17.1 0.017 15.2 17.1 3.9 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain DUF1794 PF08768.11 KFP02799.1 - 0.036 14.0 3.2 2.5 8.0 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1794) MscS_porin PF12795.7 KFP02799.1 - 0.12 11.9 42.9 1.6 8.2 33.6 2.2 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF1664 PF07889.12 KFP02799.1 - 0.18 11.9 24.4 1.7 8.7 7.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF745 PF05335.13 KFP02799.1 - 0.19 11.4 38.4 0.045 13.5 15.5 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF745) CENP-F_leu_zip PF10473.9 KFP02799.1 - 0.4 10.7 55.1 0.13 12.3 16.2 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2333 PF10095.9 KFP02799.1 - 0.46 9.4 9.6 0.44 9.5 8.7 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) Uds1 PF15456.6 KFP02799.1 - 0.52 10.5 39.8 1 9.5 17.2 3.5 1 1 2 3 3 3 0 Up-regulated During Septation BORCS7 PF16088.5 KFP02799.1 - 0.55 10.5 13.5 0.63 10.3 0.3 3.4 2 2 0 3 3 3 0 BLOC-1-related complex sub-unit 7 Spc7 PF08317.11 KFP02799.1 - 0.58 9.0 50.4 3.6 6.4 33.0 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein NPV_P10 PF05531.12 KFP02799.1 - 0.67 10.5 10.1 11 6.6 0.1 3.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Laminin_I PF06008.14 KFP02799.1 - 1.1 8.9 48.1 0.36 10.5 20.6 3.1 1 1 2 3 3 3 0 Laminin Domain I Golgin_A5 PF09787.9 KFP02799.1 - 1.3 8.5 43.4 1.3 8.5 29.6 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 ADIP PF11559.8 KFP02799.1 - 1.5 8.9 41.3 7.5 6.6 11.5 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding FPP PF05911.11 KFP02799.1 - 1.8 6.7 49.0 0.42 8.8 20.5 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil AAA_13 PF13166.6 KFP02799.1 - 2.7 6.5 37.1 61 2.0 37.1 2.0 1 1 0 1 1 1 0 AAA domain BST2 PF16716.5 KFP02799.1 - 3.1 8.5 38.3 0.91 10.2 9.0 3.4 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 SNARE PF05739.19 KFP02799.1 - 4.2 7.5 12.7 1.5 8.8 0.1 4.2 4 0 0 4 4 4 0 SNARE domain Lebercilin PF15619.6 KFP02799.1 - 5.2 6.7 50.5 9.5 5.8 27.0 2.8 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease ApoO PF09769.9 KFP02799.1 - 6.1 6.8 6.0 41 4.1 0.5 3.2 2 1 1 3 3 3 0 Apolipoprotein O GAS PF13851.6 KFP02799.1 - 6.9 6.0 51.6 0.43 9.9 27.8 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4200 PF13863.6 KFP02799.1 - 7.1 7.1 57.6 0.061 13.7 13.2 3.8 1 1 2 3 3 2 0 Domain of unknown function (DUF4200) DUF3527 PF12043.8 KFP02799.1 - 7.8 6.0 12.2 9.2 5.7 12.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) DLP_helical PF18709.1 KFP02799.1 - 8.5 5.5 31.2 1.3 8.2 5.8 3.3 1 1 1 3 3 3 0 Dynamin-like helical domain TRAP_beta PF05753.14 KFP02800.1 - 1.4e-50 171.2 0.0 1.6e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) Cpn60_TCP1 PF00118.24 KFP02801.1 - 5.1e-72 243.1 2.1 5.7e-72 242.9 2.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EST1 PF10374.9 KFP02802.1 - 2.5e-26 93.0 2.0 2.5e-26 93.0 2.0 2.5 3 0 0 3 3 3 1 Telomerase activating protein Est1 EST1_DNA_bind PF10373.9 KFP02802.1 - 8.8e-22 77.9 0.7 1.2e-21 77.4 0.7 1.2 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain MTBP_N PF14918.6 KFP02802.1 - 0.095 12.2 0.1 1.9 7.9 0.0 2.0 2 0 0 2 2 2 0 MDM2-binding Trypsin PF00089.26 KFP02803.1 - 1.2e-60 205.1 0.2 1.4e-60 204.9 0.2 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFP02803.1 - 8.5e-05 22.9 0.0 0.00018 21.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 KFP02803.1 - 0.00052 20.9 0.1 0.00086 20.2 0.1 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KFP02804.1 - 3.5e-66 223.2 0.1 3.9e-66 223.0 0.1 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFP02804.1 - 2.6e-05 24.6 0.0 4.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 KFP02804.1 - 2.9e-05 25.0 0.0 4.6e-05 24.4 0.0 1.3 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KFP02805.1 - 2.5e-54 184.4 0.0 2.7e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFP02805.1 - 0.00017 21.9 0.0 0.00031 21.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) PCI PF01399.27 KFP02806.1 - 9.8e-18 64.6 1.9 2.3e-17 63.4 1.9 1.7 1 0 0 1 1 1 1 PCI domain Cullin PF00888.22 KFP02807.1 - 1.1e-190 635.4 19.6 1.6e-190 634.8 19.6 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KFP02807.1 - 3.3e-24 84.7 0.3 1.3e-23 82.8 0.3 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain SecA_SW PF07516.13 KFP02807.1 - 0.012 15.7 0.2 0.012 15.7 0.2 3.2 3 1 0 3 3 3 0 SecA Wing and Scaffold domain PG_binding_4 PF12229.8 KFP02807.1 - 1.1 9.6 4.1 3.4 8.0 0.1 3.5 4 0 0 4 4 4 0 Putative peptidoglycan binding domain Lamp PF01299.17 KFP02808.1 - 2.7e-62 209.0 9.4 2.2e-49 167.1 0.4 2.1 2 0 0 2 2 2 2 Lysosome-associated membrane glycoprotein (Lamp) ATP-synt_S1 PF05827.12 KFP02808.1 - 6.9e-09 35.7 1.0 1.5e-06 28.1 0.0 2.3 2 0 0 2 2 2 2 Vacuolar ATP synthase subunit S1 (ATP6S1) Imm10 PF15588.6 KFP02808.1 - 0.081 13.1 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 Immunity protein 10 RabGAP-TBC PF00566.18 KFP02809.1 - 5.3e-57 192.9 0.1 7.3e-57 192.5 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ADP_ribosyl_GH PF03747.14 KFP02811.1 - 1e-53 183.0 0.0 1.1e-53 182.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Cullin_binding PF03556.15 KFP02812.1 - 3.1e-38 130.9 0.6 3.1e-38 130.9 0.6 2.0 2 1 0 2 2 2 1 Cullin binding UBA_4 PF14555.6 KFP02812.1 - 3.3e-09 36.4 2.7 4.3e-09 36.1 0.0 2.6 3 0 0 3 3 3 1 UBA-like domain VMR2 PF17055.5 KFP02812.1 - 0.087 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Viral matrix protein M2 Na_H_Exchanger PF00999.21 KFP02813.1 - 9.4e-71 238.6 41.8 1.2e-70 238.2 41.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Glyco_hydro_36 PF17167.4 KFP02813.1 - 0.074 11.7 0.4 0.11 11.1 0.4 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain DUF16 PF01519.16 KFP02813.1 - 3.2 8.3 7.0 6 7.4 6.6 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 DP PF08781.10 KFP02814.1 - 1.4e-64 216.1 2.1 4e-64 214.7 2.1 1.8 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.20 KFP02814.1 - 9.1e-27 92.9 0.1 2e-26 91.8 0.1 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain LMBR1 PF04791.16 KFP02814.1 - 0.15 10.9 1.4 0.17 10.8 1.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FAM70 PF14967.6 KFP02815.1 - 2.3e-163 543.4 6.3 2.5e-163 543.2 6.3 1.0 1 0 0 1 1 1 1 FAM70 protein DUF4064 PF13273.6 KFP02815.1 - 0.00012 22.3 12.1 0.0021 18.3 7.1 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF4064) Phage_holin_3_2 PF04550.12 KFP02815.1 - 0.19 12.3 3.9 0.6 10.7 0.4 2.3 2 0 0 2 2 2 0 Phage holin family 2 Laminin_G_1 PF00054.23 KFP02816.1 - 9.6e-30 103.5 0.0 5e-21 75.3 0.0 2.3 2 0 0 2 2 2 2 Laminin G domain Laminin_G_2 PF02210.24 KFP02816.1 - 1.5e-26 93.5 0.0 3.4e-14 53.5 0.0 2.3 2 0 0 2 2 2 2 Laminin G domain EGF_CA PF07645.15 KFP02816.1 - 5.5e-22 77.7 52.5 4.2e-08 33.3 6.9 5.0 4 0 0 4 4 4 4 Calcium-binding EGF domain Gla PF00594.20 KFP02816.1 - 7.8e-17 61.2 9.1 7.8e-17 61.2 9.1 1.8 2 0 0 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain cEGF PF12662.7 KFP02816.1 - 3.8e-16 58.7 30.4 5.6e-08 32.6 3.1 4.9 4 0 0 4 4 4 3 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFP02816.1 - 1.1e-13 51.2 59.8 6.6e-09 35.9 10.9 4.6 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site EGF PF00008.27 KFP02816.1 - 3.3e-12 46.5 43.5 3.6e-06 27.1 5.7 4.8 4 0 0 4 4 4 4 EGF-like domain hEGF PF12661.7 KFP02816.1 - 4.9e-05 23.8 32.6 0.033 14.8 1.7 5.4 4 0 0 4 4 4 3 Human growth factor-like EGF EGF_3 PF12947.7 KFP02816.1 - 0.00011 22.3 46.8 0.0046 17.1 4.5 4.8 4 0 0 4 4 4 2 EGF domain ANAPC3 PF12895.7 KFP02817.1 - 5.7e-29 100.2 16.1 3.1e-21 75.4 9.9 5.6 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KFP02817.1 - 3.8e-24 82.8 19.2 0.00015 21.6 0.1 10.5 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.28 KFP02817.1 - 9.7e-22 75.8 20.1 5e-08 32.4 0.2 8.9 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFP02817.1 - 1e-16 61.0 15.8 4.7e-10 39.6 0.1 6.3 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP02817.1 - 6.5e-16 57.2 10.3 0.0017 18.4 0.0 7.7 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFP02817.1 - 2.4e-13 49.1 5.9 1.6e-05 24.6 0.1 5.1 5 1 1 6 6 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFP02817.1 - 6.9e-12 44.8 1.8 0.00049 19.9 0.3 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFP02817.1 - 1.3e-09 38.5 5.5 0.37 11.3 3.7 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFP02817.1 - 2.9e-09 36.4 1.9 3.7e-06 26.5 0.0 5.1 5 1 0 5 5 5 1 TPR repeat TPR_17 PF13431.6 KFP02817.1 - 5e-09 35.9 0.1 1.2 9.6 0.0 6.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFP02817.1 - 4.8e-08 33.0 0.5 0.076 13.2 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFP02817.1 - 3.8e-07 30.6 11.8 0.13 12.9 0.0 5.3 5 1 0 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFP02817.1 - 2.5e-05 24.7 15.8 3.9 8.5 0.0 8.1 5 3 4 9 9 8 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KFP02817.1 - 0.00065 19.7 9.3 0.0076 16.3 2.8 3.5 3 0 0 3 3 3 1 Putative TPR-like repeat TPR_3 PF07720.12 KFP02817.1 - 0.027 14.5 2.0 7.4 6.7 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFP02817.1 - 0.065 13.9 13.0 1.3 9.9 0.5 6.1 8 0 0 8 8 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFP02817.1 - 0.29 11.2 8.0 1.5 9.0 0.3 4.3 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF5113 PF17140.4 KFP02817.1 - 3.5 7.4 10.7 3.1 7.6 0.0 4.4 4 1 1 5 5 5 0 Domain of unknown function (DUF5113) Smg4_UPF3 PF03467.15 KFP02818.1 - 3.4e-49 167.2 0.1 3.4e-49 167.2 0.1 3.4 2 1 0 2 2 2 1 Smg-4/UPF3 family zf-H2C2_2 PF13465.6 KFP02819.1 - 0.0025 18.2 0.8 0.0025 18.2 0.8 5.4 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP02819.1 - 0.011 16.4 0.1 0.011 16.4 0.1 6.0 5 0 0 5 5 5 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFP02819.1 - 0.11 12.3 0.0 0.11 12.3 0.0 4.6 6 0 0 6 6 6 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFP02819.1 - 0.14 12.7 0.1 0.14 12.7 0.1 5.3 5 0 0 5 5 5 0 Zinc finger, C2H2 type Septin PF00735.18 KFP02820.1 - 3.9e-95 318.4 0.7 3.9e-95 318.4 0.7 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KFP02820.1 - 0.00011 22.3 0.0 0.0003 20.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFP02820.1 - 0.00051 20.5 0.1 0.002 18.6 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFP02820.1 - 0.0012 19.1 0.1 0.0071 16.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KFP02820.1 - 0.0048 16.8 4.9 0.029 14.3 0.0 3.4 3 1 1 4 4 4 1 RsgA GTPase Roc PF08477.13 KFP02820.1 - 0.0049 17.1 0.1 0.027 14.7 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KFP02820.1 - 0.017 14.7 5.5 0.75 9.3 0.1 3.4 3 1 1 4 4 4 0 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 KFP02820.1 - 0.018 14.6 0.0 0.018 14.6 0.0 2.0 3 0 0 3 3 3 0 P-loop containing dynein motor region Microtub_bd PF16796.5 KFP02820.1 - 0.03 14.3 3.0 0.19 11.7 0.0 3.0 3 0 0 3 3 3 0 Microtubule binding AAA_24 PF13479.6 KFP02820.1 - 0.091 12.5 0.8 0.48 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFP02820.1 - 0.097 13.2 0.5 0.34 11.4 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 KFP02820.1 - 0.12 12.9 14.2 2.4 8.6 7.7 2.4 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KFP02820.1 - 0.15 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 KFP02820.1 - 0.58 10.2 7.7 0.85 9.7 0.0 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain MukB PF04310.12 KFP02820.1 - 0.79 9.5 3.4 23 4.7 1.0 2.9 3 0 0 3 3 3 0 MukB N-terminal Dynamin_N PF00350.23 KFP02820.1 - 0.95 9.5 4.2 0.96 9.5 0.0 2.3 2 1 0 2 2 2 0 Dynamin family SID-1_RNA_chan PF13965.6 KFP02822.1 - 0.035 12.5 0.3 0.045 12.2 0.3 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CLN3 PF02487.17 KFP02822.1 - 0.084 11.9 0.5 0.12 11.4 0.5 1.1 1 0 0 1 1 1 0 CLN3 protein KI67R PF08065.12 KFP02822.1 - 1.1 9.9 5.3 0.69 10.5 2.5 2.0 2 0 0 2 2 2 0 KI67R (NUC007) repeat OAD_gamma PF04277.13 KFP02822.1 - 1.2 9.8 9.7 17 6.1 9.7 2.2 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain TNFR_c6 PF00020.18 KFP02822.1 - 1.2 9.5 23.3 0.052 13.9 8.1 3.7 1 1 3 4 4 4 0 TNFR/NGFR cysteine-rich region Pro_isomerase PF00160.21 KFP02824.1 - 7.5e-42 143.3 0.7 8.1e-42 143.2 0.7 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ran_BP1 PF00638.18 KFP02825.1 - 4.4e-57 191.6 0.6 5e-57 191.5 0.6 1.0 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 KFP02825.1 - 5.6e-05 23.0 0.1 0.0001 22.2 0.1 1.4 1 1 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 KFP02825.1 - 0.0064 16.7 0.1 0.0079 16.5 0.1 1.1 1 0 0 1 1 1 1 VID27 PH-like domain TPR_2 PF07719.17 KFP02826.1 - 2.2e-09 36.7 0.2 1.3e-05 24.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFP02826.1 - 3.3e-08 33.0 0.1 4.4e-05 23.1 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP02826.1 - 5.2e-07 30.0 0.1 0.0024 18.5 0.0 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFP02826.1 - 7.7e-05 22.8 0.6 0.032 14.6 0.1 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFP02826.1 - 0.00051 20.0 0.1 0.01 16.0 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP02826.1 - 0.0011 19.5 0.2 0.81 10.2 0.0 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFP02826.1 - 0.011 15.7 0.1 0.37 10.9 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFP02826.1 - 0.015 15.2 0.4 4.7 7.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFP02826.1 - 0.023 14.4 0.2 0.36 10.5 0.0 2.7 2 1 1 3 3 3 0 TPR repeat TPR_9 PF13371.6 KFP02826.1 - 0.035 14.3 0.0 0.22 11.7 0.0 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFP02826.1 - 0.061 13.6 0.2 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFP02826.1 - 0.078 13.6 0.0 23 5.8 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.12 KFP02826.1 - 0.17 12.6 0.4 28 5.6 0.1 2.7 2 1 0 2 2 2 0 Sel1 repeat LIM PF00412.22 KFP02827.1 - 6.2e-63 208.9 62.4 1.7e-14 53.8 3.0 5.1 5 0 0 5 5 5 5 LIM domain zf-RRN7 PF11781.8 KFP02827.1 - 0.29 10.9 0.1 0.29 10.9 0.1 9.1 10 1 0 10 10 10 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Rab_bind PF16704.5 KFP02828.1 - 9.2e-38 128.1 7.2 9.2e-38 128.1 7.2 10.4 9 4 3 12 12 12 1 Rab binding domain GRIP PF01465.20 KFP02828.1 - 3.5e-17 62.0 0.6 1.4e-16 60.1 0.3 2.3 2 0 0 2 2 2 1 GRIP domain Sulfotransfer_1 PF00685.27 KFP02829.1 - 1.2e-91 306.9 1.6 1.4e-91 306.7 1.6 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP02829.1 - 2.5e-06 28.1 0.1 8.2e-06 26.4 0.1 1.9 1 1 0 1 1 1 1 Sulfotransferase family Fe_dep_repr_C PF02742.15 KFP02829.1 - 0.044 13.9 0.0 0.099 12.7 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain SSF PF00474.17 KFP02830.1 - 4.9e-34 117.9 31.3 6.9e-34 117.4 31.3 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Alpha_GJ PF03229.13 KFP02830.1 - 0.24 12.0 2.2 1.1 9.8 0.6 2.6 2 0 0 2 2 2 0 Alphavirus glycoprotein J Glyco_transf_29 PF00777.18 KFP02831.1 - 9.2e-37 126.9 0.0 2.1e-36 125.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) fn3 PF00041.21 KFP02832.1 - 1.3e-86 285.0 0.1 1.1e-18 67.4 0.0 6.0 5 0 0 5 5 5 5 Fibronectin type III domain I-set PF07679.16 KFP02832.1 - 2e-62 207.2 3.9 1.3e-17 63.6 0.2 7.8 7 0 0 7 7 7 7 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP02832.1 - 8.9e-46 154.4 1.1 2.5e-11 44.0 0.0 7.7 7 0 0 7 7 7 7 Immunoglobulin domain ig PF00047.25 KFP02832.1 - 1.2e-30 105.5 8.2 8.5e-06 25.9 0.1 7.6 7 0 0 7 7 7 6 Immunoglobulin domain Ig_2 PF13895.6 KFP02832.1 - 5e-27 94.1 2.2 5.2e-06 26.7 0.0 6.8 6 0 0 6 6 6 5 Immunoglobulin domain V-set PF07686.17 KFP02832.1 - 1.1e-15 57.8 18.3 0.084 13.1 0.3 10.4 7 4 1 8 8 8 5 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 KFP02832.1 - 5.6e-12 46.1 0.1 0.22 12.1 0.0 6.8 5 2 0 5 5 5 3 Purple acid Phosphatase, N-terminal domain C2-set_2 PF08205.12 KFP02832.1 - 5.6e-07 29.5 0.4 0.13 12.4 0.0 4.5 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Interfer-bind PF09294.10 KFP02832.1 - 3.3e-06 27.4 0.0 4.3 7.7 0.0 4.5 5 0 0 5 5 5 3 Interferon-alpha/beta receptor, fibronectin type III fn3_2 PF16893.5 KFP02832.1 - 2.9e-05 24.1 0.0 0.19 11.9 0.0 3.5 3 0 0 3 3 3 2 Fibronectin type III domain Ig_5 PF16681.5 KFP02832.1 - 0.00017 21.9 7.8 7.1 7.1 0.0 6.6 6 0 0 6 6 6 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain DUF4926 PF16277.5 KFP02832.1 - 0.042 13.2 0.2 7 6.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4926) RRM_1 PF00076.22 KFP02833.1 - 1.4e-10 40.8 0.0 3.1e-10 39.7 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PNRC PF15365.6 KFP02834.1 - 1.1e-07 31.5 6.7 3.6e-07 29.8 6.7 2.0 1 0 0 1 1 1 1 Proline-rich nuclear receptor coactivator motif 7tm_1 PF00001.21 KFP02835.1 - 4.5e-37 127.8 22.9 6.5e-37 127.3 22.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP02835.1 - 2.7e-09 37.2 14.9 5.3e-09 36.2 14.9 1.5 1 1 0 1 1 1 1 Olfactory receptor Alpha_L_fucos PF01120.17 KFP02836.1 - 2.2e-86 290.5 1.0 2.5e-86 290.3 1.0 1.0 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 KFP02836.1 - 1.2e-21 77.0 0.0 3.4e-21 75.6 0.0 1.8 2 0 0 2 2 2 1 Alpha-L-fucosidase C-terminal domain HMGL-like PF00682.19 KFP02837.1 - 4.5e-72 242.8 0.1 5.1e-72 242.6 0.1 1.0 1 0 0 1 1 1 1 HMGL-like AnfO_nitrog PF09582.10 KFP02837.1 - 0.16 11.3 0.0 0.53 9.6 0.0 1.7 2 0 0 2 2 2 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) Cys_knot PF00007.22 KFP02838.1 - 1.3e-12 48.0 7.5 1.3e-12 48.0 7.5 3.8 4 0 0 4 4 4 1 Cystine-knot domain IGFBP PF00219.18 KFP02838.1 - 2.8e-10 40.7 23.2 2.8e-10 40.7 23.2 6.0 3 2 2 5 5 5 1 Insulin-like growth factor binding protein VWC PF00093.18 KFP02838.1 - 1.4e-08 34.9 10.1 1.4e-08 34.9 10.1 5.2 4 3 1 5 5 5 1 von Willebrand factor type C domain TSP_1 PF00090.19 KFP02838.1 - 4.3e-06 26.8 7.1 4.3e-06 26.8 7.1 3.7 2 1 0 2 2 2 1 Thrombospondin type 1 domain 4_1_CTD PF05902.13 KFP02839.1 - 5e-49 164.8 13.0 1.8e-48 163.0 13.0 2.1 1 0 0 1 1 1 1 4.1 protein C-terminal domain (CTD) FERM_C PF09380.10 KFP02839.1 - 2.6e-25 88.6 0.1 8e-25 87.1 0.0 1.9 2 0 0 2 2 2 1 FERM C-terminal PH-like domain SAB PF04382.13 KFP02839.1 - 3.5e-23 81.4 2.9 1.1e-22 79.9 2.9 1.9 1 0 0 1 1 1 1 SAB domain FERM_M PF00373.18 KFP02839.1 - 2.8e-19 69.7 0.7 7.4e-19 68.3 0.0 2.1 2 0 0 2 2 2 1 FERM central domain FA PF08736.11 KFP02839.1 - 3.8e-19 68.5 3.3 1.2e-18 66.9 3.3 2.0 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_N PF09379.10 KFP02839.1 - 1.3e-17 63.5 0.2 4.3e-17 61.8 0.1 1.9 2 0 0 2 2 2 1 FERM N-terminal domain YAcAr PF10686.9 KFP02839.1 - 0.14 12.1 0.2 0.42 10.6 0.1 1.9 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family MBT PF02820.18 KFP02840.1 - 2.2e-94 309.8 1.3 3.6e-30 104.1 0.0 3.1 3 0 0 3 3 3 3 mbt repeat zf-C2HC PF01530.18 KFP02840.1 - 9e-12 45.0 11.4 1.7e-11 44.1 11.4 1.5 1 0 0 1 1 1 1 Zinc finger, C2HC type Glyco_hydro_2_N PF02837.18 KFP02840.1 - 0.021 14.7 0.0 8.6 6.2 0.0 2.8 3 0 0 3 3 3 0 Glycosyl hydrolases family 2, sugar binding domain Tudor-knot PF11717.8 KFP02840.1 - 0.039 13.8 3.8 0.4 10.6 0.4 3.0 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain DUF4882 PF16223.5 KFP02840.1 - 0.7 9.1 2.2 3.1 7.0 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4882) RRM_1 PF00076.22 KFP02842.1 - 6.8e-22 77.1 0.0 1.2e-13 50.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFP02842.1 - 2.2e-05 24.5 0.0 9.9e-05 22.3 0.0 2.2 1 0 0 1 1 1 1 RNA binding motif ADH_zinc_N PF00107.26 KFP02843.1 - 2.2e-21 76.2 0.0 3.4e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFP02843.1 - 2.7e-08 33.7 0.1 6.3e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFP02843.1 - 3.1e-07 31.5 0.0 6.2e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CoA_binding_2 PF13380.6 KFP02843.1 - 0.11 13.0 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 CoA binding domain DUF4265 PF14085.6 KFP02843.1 - 0.17 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) Y_phosphatase PF00102.27 KFP02844.1 - 6.1e-137 454.7 1.4 1.1e-77 260.8 0.1 2.6 3 0 0 3 3 3 2 Protein-tyrosine phosphatase MAM PF00629.23 KFP02844.1 - 7.1e-36 123.5 0.0 1.7e-35 122.3 0.0 1.7 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu fn3 PF00041.21 KFP02844.1 - 1.5e-31 108.6 1.3 4e-12 46.3 0.1 5.0 5 0 0 5 5 5 3 Fibronectin type III domain DSPc PF00782.20 KFP02844.1 - 9.8e-07 28.7 0.8 0.032 14.0 0.1 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP02844.1 - 2.9e-05 24.1 0.0 0.03 14.3 0.0 2.4 2 0 0 2 2 2 2 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFP02844.1 - 0.00022 21.4 0.0 0.097 12.8 0.0 2.5 2 0 0 2 2 2 2 Inositol hexakisphosphate Pur_ac_phosph_N PF16656.5 KFP02844.1 - 0.00032 21.2 0.1 0.2 12.2 0.0 3.6 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain ig PF00047.25 KFP02844.1 - 0.0055 16.8 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP02844.1 - 0.021 15.1 0.0 0.063 13.6 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.6 KFP02844.1 - 0.025 15.2 0.0 0.073 13.7 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFP02844.1 - 0.036 14.1 0.0 0.091 12.8 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin I-set domain PsbX PF06596.11 KFP02844.1 - 1.1 9.3 5.3 2.2 8.3 5.3 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) VWA PF00092.28 KFP02845.1 - 9.8e-103 341.8 4.6 2.8e-54 184.0 0.6 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 KFP02845.1 - 8e-38 129.4 0.2 3.1e-18 66.4 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain Matrilin_ccoil PF10393.9 KFP02845.1 - 7.8e-11 41.7 0.4 2.7e-10 39.9 0.4 2.0 1 0 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin FXa_inhibition PF14670.6 KFP02845.1 - 2.8e-09 37.1 7.3 2.8e-09 37.1 7.3 1.7 2 0 0 2 2 1 1 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFP02845.1 - 2.3e-06 27.4 1.6 2.3e-06 27.4 1.6 1.9 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF_CA PF07645.15 KFP02845.1 - 4.2e-06 26.9 5.7 8.9e-06 25.8 5.7 1.6 1 0 0 1 1 1 1 Calcium-binding EGF domain Copine PF07002.16 KFP02845.1 - 0.006 16.1 0.1 1.4 8.3 0.0 3.1 3 0 0 3 3 3 1 Copine EGF PF00008.27 KFP02845.1 - 0.024 14.9 4.0 0.057 13.7 4.0 1.7 1 0 0 1 1 1 0 EGF-like domain DUF2242 PF10001.9 KFP02845.1 - 0.03 14.5 0.3 5.7 7.1 0.0 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2242) hEGF PF12661.7 KFP02845.1 - 0.08 13.6 0.4 0.08 13.6 0.4 2.2 2 0 0 2 2 1 0 Human growth factor-like EGF EGF_3 PF12947.7 KFP02845.1 - 0.91 9.8 12.2 0.11 12.8 7.7 1.8 2 0 0 2 2 2 0 EGF domain Plasmod_Pvs28 PF06247.11 KFP02845.1 - 1.6 9.1 10.4 0.11 12.8 4.7 2.0 2 0 0 2 2 2 0 Pvs28 EGF domain Mtp PF03821.16 KFP02846.1 - 2.6e-94 315.2 15.5 2.8e-94 315.0 15.5 1.0 1 0 0 1 1 1 1 Golgi 4-transmembrane spanning transporter DUF4728 PF15860.5 KFP02846.1 - 0.0037 17.9 15.6 0.024 15.3 7.1 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4728) CybS PF05328.12 KFP02846.1 - 0.24 11.1 3.8 2.4 7.9 0.6 2.6 2 0 0 2 2 2 0 CybS, succinate dehydrogenase cytochrome B small subunit DUF1475 PF07343.11 KFP02846.1 - 0.72 9.6 8.4 0.3 10.9 4.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1475) Tetraspanin PF00335.20 KFP02846.1 - 7.1 6.3 12.8 0.73 9.5 6.8 2.1 2 1 0 2 2 2 0 Tetraspanin family Syndecan PF01034.20 KFP02847.1 - 3.9e-28 97.1 0.2 5.9e-28 96.6 0.2 1.3 1 0 0 1 1 1 1 Syndecan domain ECF_trnsprt PF12822.7 KFP02847.1 - 0.023 14.8 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Glycophorin_A PF01102.18 KFP02847.1 - 1.8 8.8 0.0 1.8 8.8 0.0 3.1 4 0 0 4 4 4 0 Glycophorin A PUF PF00806.19 KFP02848.1 - 1.4e-73 238.6 8.3 5.6e-09 35.2 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 KFP02848.1 - 0.046 14.1 0.6 5 7.5 0.1 3.6 1 1 1 3 3 3 0 CPL (NUC119) domain sCache_2 PF17200.4 KFP02848.1 - 0.091 12.6 0.0 57 3.5 0.0 3.6 4 0 0 4 4 4 0 Single Cache domain 2 Importin_rep_3 PF18806.1 KFP02848.1 - 0.15 12.1 0.2 0.83 9.7 0.0 2.2 2 0 0 2 2 2 0 Importin 13 repeat Mt_ATP-synt_B PF05405.14 KFP02848.1 - 0.86 9.2 2.7 8.9 5.9 0.1 3.1 3 0 0 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) NKAIN PF05640.14 KFP02849.1 - 1.1e-79 266.5 6.9 1.2e-79 266.4 6.9 1.0 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein Peptidase_M48 PF01435.18 KFP02851.1 - 2.1e-70 236.5 0.0 2.8e-70 236.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M48_N PF16491.5 KFP02851.1 - 9.5e-69 230.9 4.1 9.5e-69 230.9 4.1 1.7 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices DUF4710 PF15828.5 KFP02851.1 - 0.085 13.0 2.0 0.32 11.1 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) Amino_oxidase PF01593.24 KFP02852.1 - 3.7e-136 455.0 0.0 3e-135 452.0 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 KFP02852.1 - 5e-18 65.2 0.3 3.1e-17 62.7 0.0 2.5 3 0 0 3 3 2 1 SWIRM domain NAD_binding_8 PF13450.6 KFP02852.1 - 3.4e-14 52.8 0.7 7.7e-14 51.7 0.7 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFP02852.1 - 5.4e-08 32.8 0.0 2.7e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFP02852.1 - 3.2e-06 26.6 0.1 1.7e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KFP02852.1 - 5.9e-06 25.7 0.4 1.7e-05 24.2 0.4 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KFP02852.1 - 3.3e-05 23.2 0.8 7.6e-05 22.0 0.6 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KFP02852.1 - 5e-05 23.8 0.2 5e-05 23.8 0.2 3.2 4 0 0 4 4 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFP02852.1 - 0.00083 18.7 0.3 0.0015 17.9 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KFP02852.1 - 0.00085 18.1 0.4 0.00085 18.1 0.4 2.3 1 1 1 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KFP02852.1 - 0.0013 18.0 0.1 0.0025 17.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KFP02852.1 - 0.0054 16.1 1.8 0.0054 16.1 1.8 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KFP02852.1 - 0.011 15.1 3.3 0.013 14.7 0.1 2.4 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KFP02852.1 - 0.017 14.5 0.1 0.067 12.6 0.1 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KFP02852.1 - 0.045 12.8 5.4 0.11 11.6 0.3 2.2 1 1 0 2 2 2 0 Glucose inhibited division protein A MRPL52 PF18699.1 KFP02852.1 - 0.068 13.4 3.9 0.24 11.6 3.9 1.9 1 1 0 1 1 1 0 Mitoribosomal protein mL52 Lycopene_cycl PF05834.12 KFP02852.1 - 0.092 11.8 0.1 0.17 10.9 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein MCRA PF06100.11 KFP02852.1 - 0.093 11.5 0.4 0.2 10.4 0.1 1.7 1 1 0 1 1 1 0 MCRA family IlvN PF07991.12 KFP02852.1 - 0.098 12.2 0.5 0.36 10.4 0.2 1.9 1 1 1 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain SlyX PF04102.12 KFP02852.1 - 0.12 13.0 5.3 1.8 9.2 2.8 2.6 2 0 0 2 2 2 0 SlyX AgI_II_C2 PF17998.1 KFP02852.1 - 0.14 12.5 0.2 0.28 11.5 0.2 1.4 1 0 0 1 1 1 0 Cell surface antigen I/II C2 terminal domain MutS_IV PF05190.18 KFP02852.1 - 0.15 12.4 3.1 1.4 9.3 0.6 2.5 2 0 0 2 2 2 0 MutS family domain IV DASH_Dad3 PF08656.10 KFP02852.1 - 0.18 11.9 1.4 7.1 6.8 0.1 2.6 2 0 0 2 2 2 0 DASH complex subunit Dad3 Snapin_Pallidin PF14712.6 KFP02852.1 - 0.52 10.8 7.3 7 7.1 7.3 2.4 1 1 0 1 1 1 0 Snapin/Pallidin AATF-Che1 PF13339.6 KFP02852.1 - 0.78 10.4 6.1 2.5 8.8 5.9 2.0 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor DivIC PF04977.15 KFP02852.1 - 1.3 8.9 7.5 15 5.5 0.1 2.5 2 0 0 2 2 2 0 Septum formation initiator 7tm_1 PF00001.21 KFP02853.1 - 6.6e-78 261.7 14.8 8.5e-78 261.3 14.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP02853.1 - 1.3e-10 41.1 10.6 5.2e-10 39.1 10.6 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP02853.1 - 3e-05 23.8 9.0 3e-05 23.8 9.0 2.0 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP02853.1 - 0.00019 21.3 14.0 0.011 15.5 10.5 2.5 2 1 0 2 2 2 2 Olfactory receptor RRM_1 PF00076.22 KFP02855.1 - 5.1e-45 151.2 1.6 1.6e-15 56.6 0.4 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) hnRNP_Q_AcD PF18360.1 KFP02855.1 - 5e-32 109.7 0.1 1.2e-31 108.4 0.1 1.7 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain RRM_7 PF16367.5 KFP02855.1 - 4.6e-10 39.5 0.2 0.006 16.7 0.0 4.4 2 2 1 3 3 3 3 RNA recognition motif RRM_5 PF13893.6 KFP02855.1 - 1.3e-06 28.0 0.0 2.5e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP02855.1 - 0.00046 20.0 0.0 0.0065 16.3 0.0 2.7 3 0 0 3 3 3 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KFP02855.1 - 0.00052 20.0 0.1 1.7 8.8 0.1 3.9 3 1 0 3 3 3 1 Limkain b1 Nup35_RRM_2 PF14605.6 KFP02855.1 - 0.0071 16.3 0.0 15 5.7 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KFP02855.1 - 0.012 15.9 1.1 31 4.8 0.0 4.5 3 2 2 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter Spo7_2_N PF15407.6 KFP02855.1 - 0.074 12.7 0.0 11 5.7 0.0 2.5 2 0 0 2 2 2 0 Sporulation protein family 7 Cep57_MT_bd PF06657.13 KFP02856.1 - 0.0029 18.0 4.9 0.0041 17.5 4.9 1.4 1 0 0 1 1 1 1 Centrosome microtubule-binding domain of Cep57 DivIC PF04977.15 KFP02856.1 - 0.0053 16.5 5.5 0.0082 15.9 5.5 1.4 1 1 0 1 1 1 1 Septum formation initiator TolA_bind_tri PF16331.5 KFP02856.1 - 0.013 15.5 1.3 0.017 15.2 1.3 1.4 1 1 0 1 1 1 0 TolA binding protein trimerisation Fib_alpha PF08702.10 KFP02856.1 - 0.015 15.4 3.3 0.017 15.3 3.3 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Val_tRNA-synt_C PF10458.9 KFP02856.1 - 0.026 14.8 2.0 0.026 14.8 2.0 2.0 1 1 1 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Csm1_N PF18504.1 KFP02856.1 - 0.032 14.6 2.9 0.032 14.6 2.9 1.6 1 1 1 2 2 2 0 Csm1 N-terminal domain Phage_lysis PF03245.13 KFP02856.1 - 0.036 14.2 2.8 0.037 14.2 2.8 1.2 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein TMF_DNA_bd PF12329.8 KFP02856.1 - 0.046 13.7 8.4 0.056 13.5 7.4 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Bcr-Abl_Oligo PF09036.10 KFP02856.1 - 0.064 13.3 3.2 0.073 13.1 3.2 1.1 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain Spc29 PF17082.5 KFP02856.1 - 0.067 13.0 2.4 0.066 13.1 2.4 1.1 1 0 0 1 1 1 0 Spindle Pole Component 29 Prefoldin_2 PF01920.20 KFP02856.1 - 0.071 13.1 8.5 0.077 13.0 8.5 1.1 1 0 0 1 1 1 0 Prefoldin subunit FlaC_arch PF05377.11 KFP02856.1 - 0.072 13.5 1.0 0.078 13.4 1.0 1.2 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) XhlA PF10779.9 KFP02856.1 - 0.073 13.3 4.7 0.082 13.1 4.7 1.2 1 0 0 1 1 1 0 Haemolysin XhlA DUF1192 PF06698.11 KFP02856.1 - 0.082 13.0 5.9 0.18 11.8 5.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) THOC7 PF05615.13 KFP02856.1 - 0.12 12.6 8.1 0.13 12.6 8.1 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 OmpH PF03938.14 KFP02856.1 - 0.14 12.5 5.7 0.13 12.6 5.7 1.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF812 PF05667.11 KFP02856.1 - 0.14 11.0 6.8 0.14 11.0 6.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ABC_tran_Xtn PF12848.7 KFP02856.1 - 0.19 11.8 8.7 0.29 11.2 8.7 1.4 1 1 0 1 1 1 0 ABC transporter DUF3450 PF11932.8 KFP02856.1 - 0.2 10.9 3.4 0.21 10.9 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Dzip-like_N PF13815.6 KFP02856.1 - 0.25 11.3 5.7 0.28 11.2 5.7 1.0 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF4407 PF14362.6 KFP02856.1 - 0.27 10.5 3.1 0.25 10.7 3.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IATP PF04568.12 KFP02856.1 - 0.3 11.5 12.5 0.19 12.1 11.3 1.3 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP TMPIT PF07851.13 KFP02856.1 - 0.51 9.5 4.7 0.5 9.6 4.7 1.0 1 0 0 1 1 1 0 TMPIT-like protein Lipoprotein_20 PF13942.6 KFP02856.1 - 0.82 9.6 5.8 0.93 9.4 5.8 1.0 1 0 0 1 1 1 0 YfhG lipoprotein IMD PF08397.11 KFP02856.1 - 0.98 8.8 8.4 0.98 8.8 8.4 1.0 1 0 0 1 1 1 0 IRSp53/MIM homology domain Borrelia_P83 PF05262.11 KFP02856.1 - 1.1 7.7 8.1 1.1 7.7 8.1 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein UPF0242 PF06785.11 KFP02856.1 - 1.2 9.2 8.5 1.2 9.2 8.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4140 PF13600.6 KFP02856.1 - 1.5 9.3 4.3 1.5 9.3 4.3 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) LCD1 PF09798.9 KFP02856.1 - 3.2 6.1 9.3 3.2 6.1 9.3 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein Atg14 PF10186.9 KFP02856.1 - 6 5.8 8.6 6 5.8 8.6 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DnaJ PF00226.31 KFP02857.1 - 7.7e-17 61.2 1.3 7.7e-17 61.2 1.3 2.1 2 0 0 2 2 2 1 DnaJ domain DUF3089 PF11288.8 KFP02857.1 - 0.16 11.5 1.2 0.26 10.8 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3089) 7tm_1 PF00001.21 KFP02858.1 - 3.9e-43 147.7 24.5 3.9e-43 147.7 24.5 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Serpentine_r_xa PF03383.15 KFP02858.1 - 0.0099 15.9 23.8 0.024 14.6 0.8 3.2 2 1 0 3 3 3 2 Caenorhabditis serpentine receptor-like protein, class xa Pox_A21 PF05323.12 KFP02858.1 - 0.05 14.2 2.1 0.16 12.6 2.1 1.9 1 0 0 1 1 1 0 Poxvirus A21 Protein XK-related PF09815.9 KFP02860.1 - 1.6e-74 251.0 15.5 1.8e-74 250.9 15.5 1.0 1 0 0 1 1 1 1 XK-related protein Metallophos PF00149.28 KFP02861.1 - 1.4e-15 58.4 0.3 2.1e-15 57.8 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STI1 PF17830.1 KFP02861.1 - 0.13 12.2 0.0 9.4 6.3 0.0 2.3 2 0 0 2 2 2 0 STI1 domain RPA_C PF08784.11 KFP02862.1 - 9.4e-24 84.1 0.0 2.3e-23 82.8 0.0 1.6 1 1 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KFP02862.1 - 0.006 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain TFA2_Winged_2 PF18121.1 KFP02862.1 - 0.0062 16.2 0.0 0.017 14.8 0.0 1.7 1 1 0 1 1 1 1 TFA2 Winged helix domain 2 RMI2 PF16100.5 KFP02862.1 - 0.079 12.8 0.1 6.6 6.6 0.0 2.3 1 1 1 2 2 2 0 RecQ-mediated genome instability protein 2 Syntaxin_2 PF14523.6 KFP02863.1 - 3.8e-25 88.2 14.2 7.8e-25 87.2 7.9 2.3 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KFP02863.1 - 3.7e-20 71.6 0.4 7.3e-20 70.7 0.4 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KFP02863.1 - 6.4e-13 48.8 12.1 6.4e-13 48.8 12.1 1.5 2 0 0 2 2 2 1 Syntaxin Prominin PF05478.11 KFP02863.1 - 0.0011 17.0 0.7 0.0011 17.0 0.7 1.9 1 1 0 2 2 2 1 Prominin Sortilin-Vps10 PF15902.5 KFP02863.1 - 0.035 12.9 0.3 0.046 12.5 0.3 1.1 1 0 0 1 1 1 0 Sortilin, neurotensin receptor 3, Fusion_gly PF00523.18 KFP02863.1 - 0.15 10.3 3.7 1.5 7.0 0.4 2.1 2 0 0 2 2 2 0 Fusion glycoprotein F0 ABC_tran_CTD PF16326.5 KFP02863.1 - 0.43 10.9 16.2 0.16 12.2 0.8 3.9 2 2 2 4 4 4 0 ABC transporter C-terminal domain ThrE PF06738.12 KFP02863.1 - 0.43 9.9 2.5 3.9 6.8 0.1 2.1 1 1 1 2 2 2 0 Putative threonine/serine exporter MCU PF04678.13 KFP02863.1 - 0.94 9.5 10.4 0.078 13.1 1.3 2.2 1 1 1 2 2 2 0 Mitochondrial calcium uniporter PEP-utilisers_N PF05524.13 KFP02863.1 - 2.3 8.4 11.1 9.9 6.4 10.6 2.2 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Synaptobrevin PF00957.21 KFP02863.1 - 2.4 8.0 8.2 0.61 9.9 2.0 2.6 2 1 0 2 2 2 0 Synaptobrevin Noelin-1 PF12308.8 KFP02863.1 - 2.5 8.1 7.0 6.4 6.8 0.8 2.9 2 2 0 2 2 2 0 Neurogenesis glycoprotein TMPIT PF07851.13 KFP02863.1 - 5.6 6.1 11.1 2.4 7.3 2.6 2.1 1 1 1 2 2 2 0 TMPIT-like protein MBT PF02820.18 KFP02864.1 - 1.8e-49 165.9 0.0 7.8e-26 90.2 0.0 2.3 2 0 0 2 2 2 2 mbt repeat SLED PF12140.8 KFP02864.1 - 8.4e-37 126.1 0.1 1.4e-36 125.4 0.1 1.3 1 0 0 1 1 1 1 SLED domain RBR PF17208.3 KFP02864.1 - 1.5e-10 41.6 16.5 1.5e-10 41.6 16.5 2.3 2 0 0 2 2 2 1 RNA binding Region GATase PF00117.28 KFP02865.1 - 7.7e-55 185.6 0.0 1e-54 185.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CTP_synth_N PF06418.14 KFP02865.1 - 2.2e-28 99.4 0.0 2.9e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus Peptidase_C26 PF07722.13 KFP02865.1 - 1.3e-09 38.1 0.0 2.7e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 Transket_pyr PF02779.24 KFP02865.1 - 0.025 14.3 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain CITED PF04487.12 KFP02866.1 - 2.8e-78 263.1 14.4 3.1e-78 263.0 14.4 1.0 1 0 0 1 1 1 1 CITED rve PF00665.26 KFP02867.1 - 1.4e-29 102.6 0.0 2.3e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Integrase_Zn PF02022.19 KFP02867.1 - 1.6e-10 40.7 0.7 4.8e-10 39.2 0.7 1.9 1 0 0 1 1 1 1 Integrase Zinc binding domain rve_3 PF13683.6 KFP02867.1 - 0.1 12.4 0.1 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain DDE_Tnp_IS240 PF13610.6 KFP02867.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 DDE domain HU-CCDC81_euk_1 PF14908.6 KFP02868.1 - 4.2e-06 26.8 0.0 5.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 HU-CCDC81_euk_2 PF18289.1 KFP02868.1 - 1.2e-05 25.4 0.0 2.3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 RVT_1 PF00078.27 KFP02869.1 - 0.00017 21.2 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.11 KFP02869.1 - 0.7 9.6 2.8 0.43 10.3 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1725) Lig_chan PF00060.26 KFP02870.1 - 2.7e-29 102.0 0.1 7.7e-29 100.5 0.0 1.8 2 0 0 2 2 2 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFP02870.1 - 4.9e-27 94.4 0.0 4.1e-26 91.4 0.0 2.3 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFP02870.1 - 6.6e-21 74.8 0.0 1.1e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 KFP02870.1 - 0.00047 19.4 0.1 0.073 12.2 0.0 2.2 1 1 1 2 2 2 2 Receptor family ligand binding region zf-C3HC4_3 PF13920.6 KFP02871.1 - 1.2e-06 28.2 11.6 2.2e-06 27.4 11.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP02871.1 - 7.1e-05 22.6 14.6 0.00013 21.7 14.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP02871.1 - 0.00022 21.0 14.6 0.0004 20.2 14.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP02871.1 - 0.00033 20.5 13.6 0.0016 18.4 14.0 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFP02871.1 - 0.0016 18.7 13.3 0.0028 17.9 13.3 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KFP02871.1 - 0.008 16.0 9.2 0.015 15.1 9.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFP02871.1 - 0.012 15.8 8.0 0.028 14.7 8.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFP02871.1 - 0.019 15.0 10.4 0.039 14.0 10.4 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 KFP02871.1 - 0.59 10.2 4.8 1.1 9.4 4.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KFP02871.1 - 1.7 8.9 10.0 4.8 7.4 10.1 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING NAPRTase_N PF17767.1 KFP02871.1 - 9.1 6.7 11.4 7.9 6.9 0.8 4.7 4 0 0 4 4 4 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Glycolytic PF00274.19 KFP02873.1 - 1.3e-177 589.8 0.2 1.4e-177 589.6 0.2 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Ribosomal_L50 PF10501.9 KFP02874.1 - 2e-12 47.2 0.2 2.9e-12 46.7 0.0 1.3 2 0 0 2 2 2 1 Ribosomal subunit 39S Lpp-LpqN PF10738.9 KFP02874.1 - 0.048 13.1 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 Probable lipoprotein LpqN PAP2 PF01569.21 KFP02875.1 - 4e-21 75.2 0.6 7.7e-21 74.3 0.6 1.4 1 0 0 1 1 1 1 PAP2 superfamily UCH PF00443.29 KFP02876.1 - 5e-50 170.4 0.0 6.3e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP02876.1 - 1.5e-15 57.6 0.1 3.9e-14 53.0 0.1 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KFP02876.1 - 0.48 9.8 3.2 1 8.8 0.2 2.6 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Yae1_N PF09811.9 KFP02878.1 - 7.7e-18 63.9 63.5 1.8e+04 -28.3 63.5 6.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Peptidase_S49_N PF08496.10 KFP02879.1 - 5.6 7.0 10.6 9.3 6.3 10.6 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CPP1-like PF11833.8 KFP02879.1 - 7.6 6.1 7.5 13 5.4 7.5 1.4 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Ank_2 PF12796.7 KFP02880.1 - 6.6e-42 142.0 9.8 1.7e-15 57.4 0.4 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP02880.1 - 1.8e-39 133.2 10.5 7.8e-11 42.0 0.1 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP02880.1 - 5.4e-39 132.1 10.8 1.4e-09 38.3 0.0 6.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KFP02880.1 - 3.8e-33 112.5 10.5 1.3e-06 28.6 0.2 6.8 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 KFP02880.1 - 1.7e-27 92.4 1.8 0.00014 22.0 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Fez1 PF06818.15 KFP02880.1 - 0.00024 21.6 26.2 0.00024 21.6 26.2 4.7 1 1 1 4 4 4 1 Fez1 Surfac_D-trimer PF09006.11 KFP02880.1 - 2.6 8.0 6.8 2.4 8.1 3.5 2.8 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation C1q PF00386.21 KFP02881.1 - 4.3e-33 114.2 3.4 5.2e-33 114.0 3.4 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFP02881.1 - 1.5e-11 43.9 50.7 2.9e-10 39.8 32.4 2.0 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Baculo_LEF-3 PF05847.11 KFP02881.1 - 0.042 13.1 0.1 0.052 12.7 0.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus late expression factor 3 (LEF-3) CoA_transf_3 PF02515.17 KFP02882.1 - 2.1e-53 181.8 0.0 2.4e-53 181.6 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III MFS_2 PF13347.6 KFP02883.1 - 1.2e-09 37.3 4.2 1.2e-09 37.3 4.2 2.9 3 0 0 3 3 3 2 MFS/sugar transport protein 7tm_1 PF00001.21 KFP02884.1 - 1.2e-48 165.8 18.4 1.4e-48 165.5 18.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TSP_1 PF00090.19 KFP02885.1 - 4.1e-35 119.8 125.4 1.3e-09 38.1 6.6 11.0 10 1 0 10 10 10 8 Thrombospondin type 1 domain ADAM_spacer1 PF05986.14 KFP02885.1 - 7.7e-34 116.2 0.1 2.1e-33 114.8 0.0 1.8 2 0 0 2 2 2 1 ADAM-TS Spacer 1 Pep_M12B_propep PF01562.19 KFP02885.1 - 2.1e-32 112.3 0.8 4.1e-32 111.3 0.8 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 KFP02885.1 - 8.2e-27 94.4 0.0 1.6e-26 93.5 0.0 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 KFP02885.1 - 4.3e-21 75.2 7.8 4.3e-21 75.2 7.8 6.4 5 2 1 6 6 2 2 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 KFP02885.1 - 4.5e-15 56.3 0.0 1.5e-14 54.6 0.0 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFP02885.1 - 2.1e-08 34.7 0.2 6.9e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFP02885.1 - 0.0001 22.3 0.0 0.00022 21.2 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP02885.1 - 0.00015 21.4 0.0 0.00027 20.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like SAM_decarbox PF01536.16 KFP02885.1 - 0.11 11.5 0.2 0.18 10.8 0.2 1.2 1 0 0 1 1 1 0 Adenosylmethionine decarboxylase PLAC PF08686.11 KFP02885.1 - 2 9.3 7.3 15 6.4 7.3 2.8 1 0 0 1 1 1 0 PLAC (protease and lacunin) domain tRNA-synt_2b PF00587.25 KFP02886.1 - 8.9e-36 123.5 0.0 1.6e-35 122.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KFP02886.1 - 3.1e-20 72.1 0.1 7e-20 71.0 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 KFP02886.1 - 4.4e-18 65.1 0.0 3.9e-17 62.0 0.0 2.3 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.14 KFP02886.1 - 1.5e-12 47.4 0.1 3.6e-12 46.2 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain GSDH PF07995.11 KFP02887.1 - 2.7e-38 132.1 0.0 3.3e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Folate_rec PF03024.14 KFP02887.1 - 7e-07 29.3 1.0 7e-07 29.3 1.0 1.6 2 0 0 2 2 2 1 Folate receptor family p450 PF00067.22 KFP02888.1 - 1.1e-89 301.3 0.6 1.4e-89 301.0 0.6 1.0 1 0 0 1 1 1 1 Cytochrome P450 Rab5-bind PF09311.11 KFP02888.1 - 0.024 14.0 0.3 0.024 14.0 0.3 1.5 2 0 0 2 2 2 0 Rabaptin-like protein Remorin_C PF03763.13 KFP02888.1 - 0.13 12.2 0.8 0.25 11.2 0.8 1.4 1 0 0 1 1 1 0 Remorin, C-terminal region PIP49_C PF12260.8 KFP02889.1 - 7.8e-06 25.7 0.1 1.3e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Nodulin_late PF07127.11 KFP02889.1 - 1.1 9.7 3.7 1.2 9.5 1.3 2.1 2 0 0 2 2 2 0 Late nodulin protein HELP PF03451.14 KFP02890.1 - 1.5e-31 108.0 0.1 3e-31 107.1 0.1 1.5 1 0 0 1 1 1 1 HELP motif WD40 PF00400.32 KFP02890.1 - 9.8e-28 95.9 40.1 0.00021 22.0 0.8 10.7 10 1 0 10 10 10 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP02890.1 - 2.3e-06 27.8 0.1 0.00065 19.9 0.0 4.5 4 2 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PKcGMP_CC PF16808.5 KFP02890.1 - 0.049 13.5 0.2 0.098 12.5 0.2 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DPPIV_N PF00930.21 KFP02890.1 - 0.057 12.2 0.0 0.12 11.1 0.0 1.5 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region SlyX PF04102.12 KFP02890.1 - 0.67 10.6 2.5 0.73 10.5 1.3 1.7 2 0 0 2 2 2 0 SlyX FA_desaturase PF00487.24 KFP02891.1 - 1e-24 87.8 16.8 2e-24 86.8 16.8 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 KFP02891.1 - 8.4e-05 22.0 0.2 0.00019 20.8 0.2 1.7 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) zf-C2H2 PF00096.26 KFP02892.1 - 3e-19 68.3 23.3 8.8e-06 25.9 0.4 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP02892.1 - 1.1e-16 60.4 21.7 2.4e-07 30.8 0.2 4.8 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP02892.1 - 2.7e-13 49.5 20.5 0.01 16.6 0.2 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KFP02892.1 - 0.00057 20.1 6.5 1.5 8.9 0.1 3.2 1 1 2 3 3 3 2 Aberrant zinc-finger IBR PF01485.21 KFP02892.1 - 0.0064 16.7 6.7 0.0086 16.3 1.6 2.6 1 1 1 2 2 2 1 IBR domain, a half RING-finger domain zf-TRAF PF02176.18 KFP02892.1 - 0.0066 17.1 12.3 2.6 8.8 0.1 3.3 1 1 2 3 3 3 2 TRAF-type zinc finger Transpos_assoc PF13963.6 KFP02892.1 - 0.0095 16.2 5.8 0.29 11.5 0.1 3.2 2 1 1 3 3 3 1 Transposase-associated domain Raffinose_syn PF05691.12 KFP02892.1 - 0.011 13.6 0.0 0.013 13.3 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 CHORD PF04968.12 KFP02892.1 - 0.013 16.2 11.5 4.2 8.2 2.0 3.7 1 1 3 4 4 4 0 CHORD zinc_ribbon_9 PF14369.6 KFP02892.1 - 0.021 15.1 3.1 0.93 9.8 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon CCAP PF11105.8 KFP02892.1 - 0.022 14.7 4.5 0.37 10.7 0.7 2.3 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a zf_UBZ PF18439.1 KFP02892.1 - 0.03 13.9 0.9 1.4 8.5 0.2 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 KFP02892.1 - 0.033 14.5 12.0 4 7.8 0.4 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-CGNR PF11706.8 KFP02892.1 - 0.044 13.6 7.0 3 7.8 0.8 3.4 3 1 0 3 3 3 0 CGNR zinc finger zf-C2H2_11 PF16622.5 KFP02892.1 - 0.085 12.6 7.2 1.6 8.5 0.4 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 KFP02892.1 - 0.31 11.5 6.5 4.2 7.9 0.3 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type XPA_N PF01286.18 KFP02892.1 - 0.52 10.4 4.6 1.5 9.0 0.1 3.0 4 0 0 4 4 3 0 XPA protein N-terminal FOXP-CC PF16159.5 KFP02892.1 - 2.4 8.9 7.7 9.9 6.9 1.8 2.9 3 1 0 3 3 3 0 FOXP coiled-coil domain Mito_carr PF00153.27 KFP02893.1 - 1.8e-63 210.5 1.9 3.4e-23 81.4 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 KFP02894.1 - 6.9e-69 227.9 0.9 2.4e-24 85.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 KFP02894.1 - 0.046 14.1 3.1 0.35 11.3 1.2 2.9 2 2 1 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family DUF4574 PF15141.6 KFP02894.1 - 0.058 13.3 0.0 5.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 DUF5440 PF17509.2 KFP02894.1 - 0.16 11.6 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5440) tRNA-synt_1b PF00579.25 KFP02895.1 - 2.2e-24 86.3 0.0 4.1e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) WHEP-TRS PF00458.20 KFP02895.1 - 2.7e-21 75.5 0.1 6.3e-21 74.3 0.1 1.7 1 0 0 1 1 1 1 WHEP-TRS domain WD40 PF00400.32 KFP02896.1 - 3.7e-21 75.1 5.2 7.8e-05 23.4 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP02896.1 - 1.8e-12 47.4 0.0 7.5e-05 23.0 0.0 3.9 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP02896.1 - 4.1e-10 39.9 0.0 0.00021 21.2 0.0 3.3 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFP02896.1 - 0.0058 15.6 1.5 0.011 14.7 0.0 2.2 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFP02896.1 - 0.025 13.2 0.1 0.069 11.8 0.0 1.7 2 0 0 2 2 2 0 Nucleoporin Nup120/160 IFT57 PF10498.9 KFP02897.1 - 0.017 14.1 7.7 0.046 12.7 7.7 1.7 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Spc7 PF08317.11 KFP02897.1 - 0.031 13.2 12.7 0.072 12.0 9.5 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 KFP02897.1 - 0.19 9.6 2.1 0.45 8.4 2.1 1.6 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 KFP02897.1 - 0.98 9.5 4.7 1.2 9.2 1.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CENP-H PF05837.12 KFP02897.1 - 1.2 9.6 9.5 1.2 9.6 6.2 2.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) FapA PF03961.13 KFP02897.1 - 1.9 7.0 7.7 3.2 6.3 7.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A XhlA PF10779.9 KFP02897.1 - 5.1 7.4 5.1 1.1 9.5 1.3 1.9 2 0 0 2 2 2 0 Haemolysin XhlA WD40 PF00400.32 KFP02898.1 - 2.1e-40 136.0 25.9 6.2e-09 36.4 0.2 6.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP02898.1 - 6.4e-11 42.4 0.4 0.0028 17.9 0.0 4.6 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP02898.1 - 2.6e-06 27.5 0.1 0.013 15.4 0.0 2.7 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFP02898.1 - 4.7e-05 22.5 0.1 0.61 9.0 0.0 4.0 2 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFP02898.1 - 0.00013 20.8 4.3 0.098 11.3 0.1 3.9 2 1 2 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KFP02898.1 - 0.0056 16.0 0.0 2.1 7.6 0.0 2.1 2 0 0 2 2 2 2 WD40-like domain Cytochrom_D1 PF02239.16 KFP02898.1 - 0.009 14.6 0.0 0.017 13.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome D1 heme domain Env-gp36 PF09590.10 KFP02898.1 - 0.053 12.0 0.1 0.062 11.7 0.1 1.1 1 0 0 1 1 1 0 Lentivirus surface glycoprotein PD40 PF07676.12 KFP02898.1 - 0.26 11.3 4.5 15 5.7 0.0 4.6 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat zf-C3HC4_4 PF15227.6 KFP02899.1 - 5.9e-14 51.9 0.9 8.7e-14 51.4 0.9 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KFP02899.1 - 6.9e-11 42.0 0.8 9.2e-11 41.6 0.8 1.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFP02899.1 - 1.3e-10 40.9 0.2 1.8e-10 40.5 0.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP02899.1 - 1.4e-09 37.7 0.5 1.8e-09 37.3 0.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP02899.1 - 1.7e-06 28.2 1.3 2.4e-06 27.7 1.3 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFP02899.1 - 3.5e-06 26.8 0.5 4.5e-06 26.4 0.5 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KFP02899.1 - 0.0002 21.1 1.0 0.00027 20.7 1.0 1.1 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 KFP02899.1 - 0.0023 17.9 2.7 0.0049 16.8 2.7 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 KFP02899.1 - 0.01 16.0 1.6 0.015 15.4 1.6 1.2 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 KFP02899.1 - 0.023 14.5 0.1 0.029 14.2 0.1 1.2 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Baculo_IE-1 PF05290.11 KFP02899.1 - 0.031 14.2 0.4 0.039 13.9 0.4 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 KFP02899.1 - 0.032 14.1 0.9 0.046 13.6 0.9 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KFP02899.1 - 0.094 12.5 3.3 0.29 10.9 3.3 1.8 1 1 0 1 1 1 0 RING-like zinc finger Fer2 PF00111.27 KFP02899.1 - 1.1 9.2 5.2 0.28 11.1 1.3 1.9 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain PRY PF13765.6 KFP02900.1 - 7.4e-20 70.3 0.2 1.3e-19 69.5 0.2 1.4 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.28 KFP02900.1 - 2.2e-06 27.8 0.0 2.8e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 SPRY domain PRY PF13765.6 KFP02901.1 - 1.1e-19 69.7 0.1 3.3e-19 68.2 0.1 1.7 2 0 0 2 2 2 1 SPRY-associated domain SPRY PF00622.28 KFP02901.1 - 7.9e-12 45.3 0.0 9.4e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 SPRY domain DUF4723 PF15851.5 KFP02902.1 - 0.00079 19.5 7.5 0.001 19.1 7.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4723) Activin_recp PF01064.23 KFP02902.1 - 0.28 12.3 12.6 0.43 11.7 12.6 1.4 1 1 0 1 1 1 0 Activin types I and II receptor domain Toxin_TOLIP PF00087.21 KFP02902.1 - 0.34 11.2 13.0 0.71 10.2 13.1 1.6 1 1 0 1 1 1 0 Snake toxin and toxin-like protein PRY PF13765.6 KFP02903.1 - 2.2e-18 65.6 0.1 3.8e-18 64.9 0.1 1.4 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.28 KFP02903.1 - 1.5e-15 57.3 0.2 2.1e-15 56.9 0.2 1.2 1 0 0 1 1 1 1 SPRY domain Neuralized PF07177.12 KFP02903.1 - 0.0027 17.7 0.0 0.0043 17.1 0.0 1.3 1 0 0 1 1 1 1 Neuralized Amino_oxidase PF01593.24 KFP02904.1 - 1.1e-70 239.2 0.0 3.7e-69 234.2 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFP02904.1 - 1e-15 57.7 0.3 6e-15 55.2 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFP02904.1 - 3.4e-07 30.2 0.1 6.6e-06 25.9 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFP02904.1 - 1e-06 29.2 0.8 1.8e-06 28.4 0.1 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFP02904.1 - 1.1e-06 28.1 0.1 2.2e-06 27.2 0.0 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFP02904.1 - 3.5e-06 26.4 0.1 5.7e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 KFP02904.1 - 6.7e-06 25.6 0.1 1.2e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KFP02904.1 - 7.9e-06 25.2 0.0 1.3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KFP02904.1 - 1.2e-05 24.8 0.5 3.8e-05 23.1 0.5 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KFP02904.1 - 4.2e-05 22.4 0.3 6.7e-05 21.8 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KFP02904.1 - 7.5e-05 22.2 0.1 0.00011 21.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KFP02904.1 - 0.00078 18.8 0.2 0.0016 17.8 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KFP02904.1 - 0.004 16.8 1.6 0.018 14.7 0.3 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA MCRA PF06100.11 KFP02904.1 - 0.0088 14.9 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 1 MCRA family FMO-like PF00743.19 KFP02904.1 - 0.011 14.1 0.0 0.019 13.4 0.0 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 KFP02904.1 - 0.013 15.5 0.2 0.031 14.2 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KFP02904.1 - 0.026 13.4 0.4 0.039 12.8 0.4 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_7 PF13241.6 KFP02904.1 - 0.035 14.5 0.0 0.74 10.3 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.22 KFP02904.1 - 0.037 13.1 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KFP02904.1 - 0.05 13.5 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KFP02904.1 - 0.056 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF2207 PF09972.9 KFP02904.1 - 0.084 11.6 2.4 0.12 11.2 2.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TrkA_N PF02254.18 KFP02904.1 - 0.11 12.7 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.12 KFP02904.1 - 0.16 11.0 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.23 KFP02904.1 - 0.16 11.9 0.1 0.46 10.5 0.0 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus zf-C2H2 PF00096.26 KFP02905.1 - 2.9e-39 131.3 54.4 8.2e-06 26.0 0.7 9.2 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP02905.1 - 1.3e-37 126.6 69.5 1e-08 35.2 0.7 9.9 9 1 1 10 10 10 8 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP02905.1 - 4.9e-22 76.7 53.3 0.00073 20.2 0.8 9.0 9 0 0 9 9 9 8 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFP02905.1 - 1.6e-08 34.5 35.6 0.00099 19.2 2.1 6.4 4 2 2 6 6 6 4 Zinc ribbon domain zf-C2H2_11 PF16622.5 KFP02905.1 - 7.3e-08 32.0 42.4 0.044 13.6 0.2 8.8 9 0 0 9 9 9 5 zinc-finger C2H2-type zf_UBZ PF18439.1 KFP02905.1 - 3.5e-06 26.5 31.8 1.8 8.2 0.0 8.8 9 0 0 9 9 9 4 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 KFP02905.1 - 0.00015 22.0 20.7 4.5 7.7 0.0 8.1 8 1 1 9 9 9 2 Zinc-finger double-stranded RNA-binding zf-trcl PF13451.6 KFP02905.1 - 0.00028 20.7 35.7 1.7 8.6 0.6 8.1 5 3 1 6 6 6 3 Probable zinc-ribbon domain zinc_ribbon_15 PF17032.5 KFP02905.1 - 0.00088 20.0 20.8 2 9.2 0.2 4.4 2 2 1 3 3 3 2 zinc-ribbon family zf-LYAR PF08790.11 KFP02905.1 - 0.00099 19.0 19.1 2.9 7.9 0.1 8.0 9 0 0 9 9 9 1 LYAR-type C2HC zinc finger XPA_N PF01286.18 KFP02905.1 - 0.0028 17.6 29.1 4.9 7.3 0.1 8.7 9 0 0 9 9 9 1 XPA protein N-terminal HypA PF01155.19 KFP02905.1 - 0.006 16.6 23.5 1.3 9.0 1.0 4.7 2 1 2 4 4 4 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FYDLN_acid PF09538.10 KFP02905.1 - 0.0075 16.9 16.8 1.4 9.7 0.1 6.3 1 1 5 6 6 6 2 Protein of unknown function (FYDLN_acid) CpXC PF14353.6 KFP02905.1 - 0.0099 15.9 23.3 6.4 6.8 0.4 7.6 3 3 3 6 6 6 1 CpXC protein Zn_ribbon_SprT PF17283.2 KFP02905.1 - 0.011 15.6 39.8 0.48 10.4 0.2 7.4 5 3 1 6 6 6 0 SprT-like zinc ribbon domain ADK_lid PF05191.14 KFP02905.1 - 0.025 14.6 23.9 1.4 9.0 2.0 6.5 5 2 1 6 6 6 0 Adenylate kinase, active site lid DUF3268 PF11672.8 KFP02905.1 - 0.14 12.5 18.8 1.6 9.1 0.4 4.1 3 1 1 4 4 4 0 zinc-finger-containing domain Mut7-C PF01927.16 KFP02905.1 - 0.37 10.9 22.8 3.4 7.7 4.5 5.4 2 2 3 5 5 5 0 Mut7-C RNAse domain Zn_ribbon_recom PF13408.6 KFP02905.1 - 1.6 9.3 35.6 7.7 7.1 2.7 6.4 5 1 2 7 7 7 0 Recombinase zinc beta ribbon domain zf-C2H2 PF00096.26 KFP02906.1 - 1.6e-09 37.7 6.0 9.3e-05 22.7 0.4 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP02906.1 - 1.4e-08 34.8 1.1 1.4e-08 34.8 1.1 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_11 PF16622.5 KFP02906.1 - 3.5e-07 29.8 3.9 0.00025 20.7 0.3 2.1 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KFP02906.1 - 0.0011 19.6 6.0 0.15 13.0 0.5 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger DUF2256 PF10013.9 KFP02906.1 - 0.0018 18.4 1.3 0.083 13.0 0.2 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-trcl PF13451.6 KFP02906.1 - 0.016 15.1 0.4 0.053 13.4 0.0 1.8 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-H2C2_5 PF13909.6 KFP02906.1 - 0.02 14.6 11.8 0.17 11.6 0.1 2.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain PRY PF13765.6 KFP02907.1 - 8.3e-22 76.6 0.2 1.4e-21 75.8 0.2 1.4 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.28 KFP02907.1 - 3e-16 59.6 0.1 3.8e-16 59.3 0.1 1.1 1 0 0 1 1 1 1 SPRY domain PUL PF08324.11 KFP02908.1 - 0.013 14.8 0.6 0.34 10.1 0.3 2.3 1 1 1 2 2 2 0 PUL domain MAS20 PF02064.15 KFP02909.1 - 1.3e-46 157.8 0.8 2.5e-46 157.0 0.8 1.4 1 1 0 1 1 1 1 MAS20 protein import receptor RSN1_7TM PF02714.15 KFP02909.1 - 0.027 13.8 0.0 0.034 13.5 0.0 1.1 1 0 0 1 1 1 0 Calcium-dependent channel, 7TM region, putative phosphate TPR_1 PF00515.28 KFP02909.1 - 0.084 12.7 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat RRM_1 PF00076.22 KFP02910.1 - 5.1e-29 99.9 0.9 4.5e-15 55.2 0.0 3.4 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP02910.1 - 1.7e-09 37.7 0.2 0.0015 18.6 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif RRM_Rrp7 PF17799.1 KFP02910.1 - 0.00044 20.1 1.7 0.0057 16.5 0.1 2.7 3 0 0 3 3 3 1 Rrp7 RRM-like N-terminal domain Nup35_RRM PF05172.13 KFP02910.1 - 0.0012 18.8 0.1 1.9 8.5 0.1 2.6 2 1 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 KFP02910.1 - 0.0029 17.6 0.0 0.088 12.8 0.0 2.6 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Cellulose_synt PF03552.14 KFP02910.1 - 0.17 10.3 7.9 0.24 9.8 7.9 1.2 1 0 0 1 1 1 0 Cellulose synthase DUF2228 PF10228.9 KFP02910.1 - 4.1 7.1 12.3 3.5 7.3 10.7 1.7 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2228) RBB1NT PF08169.11 KFP02911.1 - 1.6e-34 117.9 0.4 1.6e-34 117.9 0.4 2.7 2 0 0 2 2 2 1 RBB1NT (NUC162) domain ARID PF01388.21 KFP02911.1 - 1.5e-20 73.7 0.1 3.1e-20 72.6 0.1 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Tudor-knot PF11717.8 KFP02911.1 - 2.7e-11 43.2 0.3 2.7e-11 43.2 0.3 2.3 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Tudor_2 PF18104.1 KFP02911.1 - 2.9e-05 23.6 0.8 0.00015 21.3 0.2 2.4 2 0 0 2 2 2 1 Jumonji domain-containing protein 2A Tudor domain DUF4537 PF15057.6 KFP02911.1 - 0.013 15.5 0.1 2.5 8.1 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) polyprenyl_synt PF00348.17 KFP02912.1 - 4.4e-62 209.5 0.0 5.7e-62 209.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase LRR_4 PF12799.7 KFP02913.1 - 4.1e-14 52.5 24.0 0.0001 22.6 2.0 5.3 2 2 2 5 5 5 5 Leucine Rich repeats (2 copies) CAP_GLY PF01302.25 KFP02913.1 - 8e-14 51.4 0.2 1.5e-13 50.5 0.2 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_9 PF14580.6 KFP02913.1 - 1.4e-11 44.2 4.2 1.3e-10 41.0 0.8 2.4 1 1 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 KFP02913.1 - 2.2e-10 40.1 20.5 8.3e-05 22.3 6.7 4.9 2 1 1 4 4 4 4 Leucine rich repeat Ubiquitin_2 PF14560.6 KFP02913.1 - 2.9e-06 27.6 0.0 1e-05 25.9 0.0 2.0 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_6 PF13516.6 KFP02913.1 - 0.0017 18.2 14.7 0.41 10.8 0.3 6.2 7 0 0 7 7 7 1 Leucine Rich repeat LRR_1 PF00560.33 KFP02913.1 - 1.3 9.9 15.9 59 4.8 0.0 6.6 6 1 0 6 6 6 0 Leucine Rich Repeat Galactosyl_T PF01762.21 KFP02914.1 - 4.2e-29 101.8 0.0 2.2e-25 89.7 0.0 2.2 2 0 0 2 2 2 2 Galactosyltransferase G-gamma PF00631.22 KFP02915.1 - 3.5e-16 59.0 0.0 4.2e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 GGL domain G2F PF07474.12 KFP02916.1 - 3.7e-72 242.0 0.3 6.4e-72 241.2 0.3 1.4 1 0 0 1 1 1 1 G2F domain Ldl_recept_b PF00058.17 KFP02916.1 - 2.2e-38 130.4 2.9 3.7e-11 43.3 0.1 4.7 4 0 0 4 4 4 3 Low-density lipoprotein receptor repeat class B EGF_3 PF12947.7 KFP02916.1 - 1.5e-31 108.3 102.1 4e-09 36.5 10.2 6.6 6 0 0 6 6 6 5 EGF domain NIDO PF06119.14 KFP02916.1 - 2.7e-22 79.5 0.4 9.9e-22 77.7 0.4 2.1 1 0 0 1 1 1 1 Nidogen-like cEGF PF12662.7 KFP02916.1 - 2.3e-20 72.2 51.6 6.9e-08 32.3 1.4 6.8 6 0 0 6 6 6 5 Complement Clr-like EGF-like EGF_CA PF07645.15 KFP02916.1 - 2.4e-20 72.4 90.2 7.7e-09 35.6 7.0 6.8 6 0 0 6 6 5 5 Calcium-binding EGF domain Thyroglobulin_1 PF00086.18 KFP02916.1 - 2.2e-18 65.7 1.6 9.5e-18 63.6 1.6 2.2 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat FXa_inhibition PF14670.6 KFP02916.1 - 2.3e-17 63.0 88.9 2.8e-08 33.9 7.1 6.6 5 1 1 6 6 6 4 Coagulation Factor Xa inhibitory site EGF PF00008.27 KFP02916.1 - 6.8e-11 42.3 92.7 0.006 16.9 7.1 7.2 6 1 1 7 7 7 6 EGF-like domain SGL PF08450.12 KFP02916.1 - 9.7e-06 25.3 0.1 5.1e-05 23.0 0.1 2.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region EGF_MSP1_1 PF12946.7 KFP02916.1 - 0.00014 21.8 65.9 0.014 15.4 6.7 5.9 6 0 0 6 6 5 4 MSP1 EGF domain 1 hEGF PF12661.7 KFP02916.1 - 0.013 16.1 4.6 0.013 16.1 4.6 8.2 7 1 0 7 7 6 0 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 KFP02916.1 - 1 9.7 52.0 0.12 12.7 4.3 5.9 5 0 0 5 5 5 0 Pvs28 EGF domain PspB PF06667.12 KFP02917.1 - 2.5 8.2 7.9 0.45 10.6 3.4 2.1 2 0 0 2 2 2 0 Phage shock protein B ERO1 PF04137.15 KFP02918.1 - 1.4e-127 425.8 0.0 1.6e-127 425.6 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Death PF00531.22 KFP02919.1 - 1.4e-09 38.0 0.0 2.5e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Death domain DUF1307 PF06998.11 KFP02919.1 - 0.026 14.5 0.7 0.051 13.6 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1307) Gal-bind_lectin PF00337.22 KFP02920.1 - 8.9e-78 258.3 0.0 3.7e-39 133.3 0.0 2.1 2 0 0 2 2 2 2 Galactoside-binding lectin WIF PF02019.18 KFP02920.1 - 0.00022 21.0 0.0 0.3 10.8 0.0 2.5 2 0 0 2 2 2 2 WIF domain Spectrin PF00435.21 KFP02921.1 - 4.2e-71 236.1 33.6 1e-22 80.6 8.6 4.4 4 0 0 4 4 4 4 Spectrin repeat CH PF00307.31 KFP02921.1 - 1.2e-53 179.9 0.4 7e-27 93.8 0.0 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KFP02921.1 - 7.8e-28 96.4 0.0 3.9e-27 94.2 0.0 2.3 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_1 PF00036.32 KFP02921.1 - 7.4e-09 34.5 1.0 0.004 16.6 0.0 3.0 2 0 0 2 2 2 2 EF hand CAMSAP_CH PF11971.8 KFP02921.1 - 1.5e-08 34.4 0.0 3.2e-07 30.1 0.0 2.5 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_8 PF13833.6 KFP02921.1 - 1.8e-06 27.7 2.7 4.8e-06 26.3 0.3 2.9 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 KFP02921.1 - 3.9e-06 27.2 0.4 3.9e-06 27.2 0.4 2.8 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP02921.1 - 0.00011 21.9 3.7 0.024 14.5 0.5 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_11 PF08976.11 KFP02921.1 - 0.04 14.8 0.2 0.21 12.5 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain IATP PF04568.12 KFP02921.1 - 0.054 13.9 5.7 0.31 11.5 0.7 3.3 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Nsp1_C PF05064.13 KFP02921.1 - 0.078 12.8 0.2 0.078 12.8 0.2 4.9 4 2 0 5 5 5 0 Nsp1-like C-terminal region XisI PF08869.11 KFP02921.1 - 0.24 11.8 6.6 0.075 13.4 1.2 2.7 2 0 0 2 2 2 0 XisI protein Met_synt_B12 PF02965.17 KFP02922.1 - 4.6e-114 380.5 0.0 7.4e-114 379.8 0.0 1.3 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 KFP02922.1 - 8.6e-79 265.1 0.0 1.8e-78 264.1 0.0 1.6 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 KFP02922.1 - 4.4e-58 196.8 0.1 1.7e-57 194.9 0.0 2.0 2 0 0 2 2 2 1 Pterin binding enzyme B12-binding_2 PF02607.17 KFP02922.1 - 3.9e-24 84.9 0.0 1.1e-23 83.5 0.0 1.8 1 0 0 1 1 1 1 B12 binding domain B12-binding PF02310.19 KFP02922.1 - 6e-18 65.0 0.2 1.8e-17 63.5 0.2 1.8 1 0 0 1 1 1 1 B12 binding domain CdhD PF03599.16 KFP02922.1 - 0.005 15.6 0.1 0.009 14.8 0.1 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit NPR1_like_C PF12313.8 KFP02922.1 - 0.063 12.8 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 NPR1/NIM1 like defence protein C terminal IPT PF01745.16 KFP02922.1 - 0.072 12.5 0.1 0.2 11.0 0.1 1.8 1 0 0 1 1 1 0 Isopentenyl transferase PMP22_Claudin PF00822.20 KFP02923.1 - 1.3e-09 38.1 0.0 1.5e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP02923.1 - 6.3e-06 26.1 0.0 8.2e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction MoaC PF01967.21 KFP02924.1 - 1.3e-28 99.8 0.0 2e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 KFP02925.1 - 7.6e-43 145.5 0.0 1.1e-42 144.9 0.0 1.3 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KFP02925.1 - 1.1e-32 113.8 0.1 1.6e-32 113.2 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KFP02925.1 - 4.2e-10 40.0 0.0 8.9e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KFP02925.1 - 1e-05 25.7 0.0 2.8e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Lipoprotein_9 PF03180.14 KFP02925.1 - 0.14 11.2 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 NLPA lipoprotein LRR_8 PF13855.6 KFP02926.1 - 1.5e-43 146.4 51.4 1.1e-12 47.5 4.2 3.5 1 1 4 5 5 5 5 Leucine rich repeat I-set PF07679.16 KFP02926.1 - 7e-15 54.9 0.0 1.4e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_5 PF13306.6 KFP02926.1 - 5.3e-14 52.3 0.1 4.4e-11 42.8 0.0 2.2 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) Ig_3 PF13927.6 KFP02926.1 - 3.5e-13 49.9 0.0 1.1e-12 48.4 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain LRR_4 PF12799.7 KFP02926.1 - 5.1e-13 49.0 24.3 1.3e-05 25.5 2.8 4.7 2 2 3 5 5 5 3 Leucine Rich repeats (2 copies) ig PF00047.25 KFP02926.1 - 7.8e-10 38.8 0.0 1.6e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.21 KFP02926.1 - 9.7e-08 32.3 0.1 7.6e-07 29.4 0.0 2.5 2 0 0 2 2 2 1 Fibronectin type III domain LRR_9 PF14580.6 KFP02926.1 - 1.1e-06 28.2 6.6 0.00021 20.8 1.0 2.3 1 1 1 2 2 2 2 Leucine-rich repeat Ig_2 PF13895.6 KFP02926.1 - 1.9e-05 24.9 0.0 5.4e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFP02926.1 - 0.0049 16.9 0.1 0.035 14.1 0.0 2.2 2 0 0 2 2 2 1 C17orf99 Ig domain LRR_1 PF00560.33 KFP02926.1 - 0.018 15.5 23.5 1.9 9.3 0.7 6.9 7 1 1 8 8 6 0 Leucine Rich Repeat LRRCT PF01463.24 KFP02926.1 - 0.036 14.6 0.0 0.14 12.8 0.0 2.1 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain Bromo_TP PF07524.13 KFP02927.1 - 6.8e-22 77.3 0.3 1.4e-21 76.3 0.0 1.7 2 0 0 2 2 2 1 Bromodomain associated MAGE_N PF12440.8 KFP02927.1 - 0.83 10.4 4.3 11 6.8 0.1 2.6 2 1 0 2 2 2 0 Melanoma associated antigen family N terminal Dicer_dimer PF03368.14 KFP02928.1 - 0.002 18.3 0.0 0.0048 17.0 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain dsrm PF00035.26 KFP02928.1 - 0.027 15.2 0.0 0.089 13.5 0.0 2.0 1 0 0 1 1 1 0 Double-stranded RNA binding motif OGFr_N PF04664.13 KFP02928.1 - 0.07 12.6 0.0 0.34 10.4 0.0 1.9 2 0 0 2 2 2 0 Opioid growth factor receptor (OGFr) conserved region PfkB PF00294.24 KFP02931.1 - 1.4e-58 198.6 0.1 1.8e-58 198.3 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KFP02931.1 - 6.7e-06 25.7 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Glyco_tranf_2_5 PF13712.6 KFP02931.1 - 0.2 11.3 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family BRE PF06113.12 KFP02932.1 - 7e-140 465.4 0.0 7.9e-140 465.2 0.0 1.0 1 0 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) UQ_con PF00179.26 KFP02932.1 - 0.012 15.3 2.5 1.5 8.4 0.1 2.7 3 0 0 3 3 3 0 Ubiquitin-conjugating enzyme Ank PF00023.30 KFP02932.1 - 0.11 13.0 0.1 5.8 7.5 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat UL17 PF17640.2 KFP02932.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized UL17 bZIP_1 PF00170.21 KFP02933.1 - 5.7e-09 35.9 19.7 9.4e-09 35.3 19.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFP02933.1 - 1.1e-05 25.4 19.3 2e-05 24.6 19.3 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFP02933.1 - 3e-05 24.5 14.1 5e-05 23.7 14.1 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor ASD2 PF08687.11 KFP02933.1 - 0.0051 16.4 3.9 0.0073 15.9 3.9 1.2 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 UPF0242 PF06785.11 KFP02933.1 - 0.038 14.1 6.0 0.058 13.5 6.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF5320 PF17253.2 KFP02933.1 - 0.29 12.2 1.6 0.49 11.5 1.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5320) APG6_N PF17675.1 KFP02933.1 - 1.6 9.3 13.9 2.9 8.4 13.9 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Spc7 PF08317.11 KFP02933.1 - 2.7 6.8 10.6 3.7 6.3 10.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein PEHE PF15275.6 KFP02933.1 - 2.9 8.5 9.3 0.45 11.1 4.9 2.0 2 0 0 2 2 2 0 PEHE domain Pox_G5 PF04599.12 KFP02933.1 - 4.7 6.1 4.3 6.4 5.7 4.3 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein Lipase_GDSL PF00657.22 KFP02934.1 - 9.5e-70 234.6 0.0 3.5e-22 79.4 0.0 3.2 3 0 0 3 3 3 3 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KFP02934.1 - 5.3e-25 88.9 1.9 6.2e-08 33.2 1.2 4.5 3 3 0 3 3 3 3 GDSL-like Lipase/Acylhydrolase family DUF5351 PF17302.2 KFP02934.1 - 0.31 11.3 1.7 59 4.0 0.1 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5351) Metallophos PF00149.28 KFP02935.1 - 1.4e-39 136.7 0.1 1.7e-39 136.4 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFP02935.1 - 2.2e-16 60.0 0.8 3.7e-16 59.3 0.4 1.6 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain EF-hand_1 PF00036.32 KFP02937.1 - 5.9e-44 144.4 9.7 3.8e-10 38.6 0.4 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFP02937.1 - 5.9e-37 126.0 3.0 2.1e-19 69.7 0.8 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFP02937.1 - 4.7e-35 119.2 9.9 4.2e-15 55.3 0.3 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KFP02937.1 - 6e-32 106.8 5.0 1.1e-09 37.4 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFP02937.1 - 7.3e-28 94.8 6.8 1.1e-06 27.8 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KFP02937.1 - 5.6e-16 58.6 0.2 1.9e-09 37.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KFP02937.1 - 1.5e-09 37.7 0.5 4.3e-05 23.4 0.1 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFP02937.1 - 5.4e-08 33.2 0.0 0.003 17.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 KFP02937.1 - 2.1e-06 28.5 0.0 0.0008 20.3 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 KFP02937.1 - 9.8e-06 25.5 0.0 0.037 14.0 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KFP02937.1 - 2.1e-05 24.5 0.2 6.9e-05 22.9 0.1 2.0 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 KFP02937.1 - 0.00015 21.8 4.3 0.026 14.7 0.3 2.9 1 1 1 2 2 2 2 Dockerin type I domain DUF1103 PF06513.11 KFP02937.1 - 0.00074 19.2 1.6 0.00087 19.0 1.6 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.13 KFP02937.1 - 0.00078 19.4 0.8 0.65 9.9 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein TerB PF05099.13 KFP02937.1 - 0.0018 18.2 0.4 0.49 10.4 0.0 2.1 1 1 1 2 2 2 1 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.16 KFP02937.1 - 0.0039 17.5 1.2 1.5 9.2 0.1 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb4 DUF5580 PF17743.1 KFP02937.1 - 0.0052 15.4 0.0 0.0053 15.4 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 KFP02937.1 - 0.0062 16.4 0.7 0.33 10.8 0.2 2.2 1 1 1 2 2 2 1 SurA N-terminal domain Poly_export PF02563.16 KFP02937.1 - 0.0089 16.2 0.1 0.55 10.5 0.0 3.0 1 1 1 2 2 2 1 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 KFP02937.1 - 0.011 16.2 0.0 0.78 10.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4497) EF-hand_14 PF17959.1 KFP02937.1 - 0.019 15.3 0.1 8 6.9 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain SurA_N_3 PF13624.6 KFP02937.1 - 0.043 13.6 0.3 0.65 9.8 0.3 2.0 1 1 1 2 2 2 0 SurA N-terminal domain MotA_activ PF09114.10 KFP02937.1 - 0.047 13.8 0.4 0.78 9.9 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain Fe_hyd_lg_C PF02906.14 KFP02937.1 - 0.063 12.9 0.5 0.25 11.0 0.5 1.9 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain TetR_C_7 PF14246.6 KFP02937.1 - 0.066 13.2 0.1 6.8 6.8 0.0 2.7 2 1 1 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain dCache_2 PF08269.11 KFP02937.1 - 0.079 12.1 0.1 6.2 5.9 0.1 2.4 1 1 1 2 2 2 0 Cache domain RuvA_C PF07499.13 KFP02937.1 - 0.1 13.1 0.1 11 6.5 0.0 2.9 3 0 0 3 3 3 0 RuvA, C-terminal domain CMD PF02627.20 KFP02937.1 - 0.18 11.8 0.1 6.2 7.0 0.0 2.5 1 1 1 2 2 2 0 Carboxymuconolactone decarboxylase family TPR_2 PF07719.17 KFP02938.1 - 4.5e-25 85.7 20.0 3.4e-05 23.6 0.1 10.8 12 0 0 12 12 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 KFP02938.1 - 9.3e-20 69.6 12.0 3.7e-05 23.3 0.0 9.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFP02938.1 - 7.6e-18 63.7 18.8 0.017 15.9 0.1 10.7 5 2 5 10 10 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 KFP02938.1 - 1.6e-17 62.9 2.5 4.8e-05 22.9 0.0 6.9 6 1 2 8 8 8 4 TPR repeat TPR_16 PF13432.6 KFP02938.1 - 2.1e-15 57.1 8.7 3.1e-05 24.5 0.2 5.9 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFP02938.1 - 3.5e-15 56.1 22.2 8.7e-06 25.9 0.4 7.5 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFP02938.1 - 6.2e-15 54.1 20.9 0.0015 18.6 0.0 10.0 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_17 PF13431.6 KFP02938.1 - 1.3e-14 53.5 3.4 0.033 14.6 0.0 6.4 7 0 0 7 7 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 KFP02938.1 - 9.2e-10 38.5 10.9 0.22 11.7 3.0 5.5 3 2 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFP02938.1 - 5e-09 36.5 19.6 0.009 16.5 0.0 7.7 5 4 2 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP02938.1 - 6.2e-09 36.0 18.1 0.0031 17.7 2.5 6.0 5 1 1 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KFP02938.1 - 1.2e-08 34.4 12.2 0.057 13.5 0.0 8.8 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFP02938.1 - 2.2e-06 27.3 18.5 0.024 14.5 0.0 7.0 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFP02938.1 - 3.2e-06 27.4 18.3 0.6 10.9 0.1 8.9 10 0 0 10 10 7 2 Tetratricopeptide repeat TPR_20 PF14561.6 KFP02938.1 - 1e-05 25.8 9.2 0.014 15.7 1.5 4.6 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFP02938.1 - 2.6e-05 23.6 11.5 0.00018 20.9 0.8 4.2 3 1 0 3 3 3 1 Tetratricopeptide repeat DUF3808 PF10300.9 KFP02938.1 - 0.00011 21.1 3.1 0.00044 19.1 0.1 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF3808) NARP1 PF12569.8 KFP02938.1 - 0.0012 17.9 2.0 0.28 10.0 0.0 3.3 2 2 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_MalT PF17874.1 KFP02938.1 - 0.0021 17.5 22.0 0.48 9.7 0.5 5.1 3 2 1 4 4 4 3 MalT-like TPR region TPR_3 PF07720.12 KFP02938.1 - 0.012 15.6 0.9 19 5.3 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.10 KFP02938.1 - 0.012 14.6 5.0 5.5 5.9 1.0 3.4 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.14 KFP02938.1 - 0.023 15.3 7.2 8 7.4 0.1 5.1 4 0 0 4 4 3 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KFP02938.1 - 0.045 13.4 8.1 11 5.7 0.3 4.5 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) MIT PF04212.18 KFP02938.1 - 0.085 12.9 7.0 7.8 6.7 0.0 5.9 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain RB_B PF01857.20 KFP02938.1 - 0.12 12.4 0.6 0.5 10.4 0.2 2.2 2 0 0 2 2 2 0 Retinoblastoma-associated protein B domain PPR PF01535.20 KFP02938.1 - 0.18 12.1 0.7 1.2e+02 3.2 0.0 4.6 5 0 0 5 5 3 0 PPR repeat MAS20 PF02064.15 KFP02938.1 - 0.32 11.1 2.5 17 5.5 0.0 3.9 4 0 0 4 4 4 0 MAS20 protein import receptor DUF3209 PF11483.8 KFP02938.1 - 1.3 9.5 5.2 4.4 7.8 0.8 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3209) EF-hand_6 PF13405.6 KFP02939.1 - 1.4e-09 37.1 0.3 0.00036 20.2 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KFP02939.1 - 1.1e-08 35.4 3.2 1.6e-08 34.9 1.7 1.9 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP02939.1 - 3.8e-07 29.2 0.4 0.0007 19.0 0.2 2.7 2 1 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KFP02939.1 - 0.00089 18.6 2.8 0.0069 15.8 0.7 2.8 2 1 1 3 3 3 1 EF hand EF-hand_8 PF13833.6 KFP02939.1 - 0.012 15.5 1.1 0.053 13.4 0.4 2.4 2 1 0 2 2 2 0 EF-hand domain pair PBECR3 PF18812.1 KFP02939.1 - 0.18 11.8 4.7 1.9 8.5 0.4 2.1 1 1 1 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 Cript PF10235.9 KFP02940.1 - 1.3e-24 86.6 1.1 1.3e-24 86.6 1.1 1.6 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT zf-BED PF02892.15 KFP02940.1 - 0.22 11.6 4.2 0.7 10.0 0.5 2.4 2 0 0 2 2 2 0 BED zinc finger PIG-F PF06699.11 KFP02941.1 - 8.9e-44 149.8 12.3 1.1e-43 149.5 12.3 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Ras PF00071.22 KFP02942.1 - 8.6e-42 142.5 0.0 9.8e-42 142.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP02942.1 - 4.4e-11 43.0 0.0 6.2e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP02942.1 - 0.01 15.3 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP02942.1 - 0.04 13.5 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain TMEM247 PF15444.6 KFP02943.1 - 3.2e-07 30.6 0.3 3.3e-07 30.6 0.3 1.1 1 0 0 1 1 1 1 Transmembrane protein 247 PAS_3 PF08447.12 KFP02944.1 - 2.2e-27 95.2 0.0 1.4e-20 73.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KFP02944.1 - 1.9e-22 79.5 0.2 5e-19 68.5 0.1 2.6 2 0 0 2 2 2 2 PAS domain HIF-1a_CTAD PF08778.10 KFP02944.1 - 3.2e-19 68.3 1.0 7.4e-19 67.1 1.0 1.7 1 0 0 1 1 1 1 HIF-1 alpha C terminal transactivation domain HIF-1 PF11413.8 KFP02944.1 - 2.1e-18 65.4 2.6 2.1e-17 62.2 2.1 2.4 2 0 0 2 2 2 1 Hypoxia-inducible factor-1 PAS PF00989.25 KFP02944.1 - 5.5e-14 52.1 0.7 3e-06 27.2 0.0 2.6 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 KFP02944.1 - 2.2e-08 34.3 0.0 0.0075 16.5 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KFP02944.1 - 4.2e-07 30.2 0.0 0.038 14.2 0.0 2.4 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 KFP02944.1 - 0.074 13.0 0.4 0.14 12.1 0.4 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Corona_I PF03187.14 KFP02944.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Corona nucleocapsid I protein Pkinase PF00069.25 KFP02945.1 - 1.4e-65 221.3 0.0 2.3e-65 220.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP02945.1 - 1e-37 129.9 0.0 1.7e-37 129.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KFP02945.1 - 3.8e-33 113.1 22.9 6.7e-17 61.1 5.4 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KFP02945.1 - 6.8e-10 39.5 0.1 1.6e-09 38.3 0.1 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain FTA2 PF13095.6 KFP02945.1 - 0.0012 18.5 0.1 0.2 11.3 0.0 2.5 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KFP02945.1 - 0.0056 16.0 0.0 0.0096 15.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFP02945.1 - 0.022 14.1 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFP02945.1 - 0.085 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain C1_2 PF03107.16 KFP02945.1 - 0.09 13.1 17.4 0.68 10.3 3.2 2.7 2 0 0 2 2 2 0 C1 domain APH PF01636.23 KFP02945.1 - 0.11 12.4 0.1 0.33 10.8 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Zf_RING PF16744.5 KFP02945.1 - 0.44 10.7 14.2 1.5 9.0 5.0 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger PHD PF00628.29 KFP02945.1 - 8.9 6.3 21.4 1.7 8.6 4.9 2.6 2 0 0 2 2 2 0 PHD-finger C2 PF00168.30 KFP02946.1 - 2.1e-15 56.9 0.0 2.3e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 C2 domain SIX1_SD PF16878.5 KFP02947.1 - 7.9e-25 87.5 0.8 7.9e-25 87.5 0.8 1.7 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 KFP02947.1 - 1.1e-14 54.0 2.0 1.3e-14 53.7 0.4 1.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KFP02947.1 - 5.1e-13 48.7 1.1 1.1e-12 47.6 1.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 KFP02947.1 - 0.003 17.0 0.5 0.011 15.2 0.1 2.1 3 0 0 3 3 3 1 Homeodomain leucine-zipper encoding, Homez HTH_3 PF01381.22 KFP02947.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix YdaS_antitoxin PF15943.5 KFP02947.1 - 0.045 13.6 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Menin PF05053.13 KFP02947.1 - 0.67 8.3 2.3 0.78 8.0 2.3 1.1 1 0 0 1 1 1 0 Menin SIX1_SD PF16878.5 KFP02948.1 - 5.2e-42 142.9 0.0 7.7e-42 142.3 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator, SIX1, N-terminal SD domain Methyltransf_16 PF10294.9 KFP02949.1 - 4.5e-17 62.3 0.1 5.3e-17 62.1 0.1 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_11 PF08241.12 KFP02949.1 - 0.00068 20.2 0.0 0.0011 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP02949.1 - 0.0011 19.6 0.0 0.0017 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FAE1_CUT1_RppA PF08392.12 KFP02949.1 - 0.0038 16.6 0.1 0.0055 16.0 0.1 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein Methyltransf_23 PF13489.6 KFP02949.1 - 0.0042 16.9 0.0 0.0094 15.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP02949.1 - 0.018 15.8 0.0 0.044 14.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Sensor_TM1 PF13755.6 KFP02949.1 - 0.17 11.7 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain Peptidase_S9 PF00326.21 KFP02950.1 - 2.6e-34 118.6 0.0 4.7e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 KFP02950.1 - 1.3e-25 90.1 1.3 2.2e-25 89.3 1.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Myb_DNA-bind_5 PF13873.6 KFP02950.1 - 0.0073 16.4 1.9 0.052 13.6 0.6 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Hydrolase_4 PF12146.8 KFP02950.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KFP02950.1 - 0.031 14.1 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Alpha-amylase PF00128.24 KFP02951.1 - 6.4e-79 265.9 1.3 9.2e-79 265.4 1.3 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain SLC3A2_N PF16028.5 KFP02951.1 - 1.8e-05 24.2 0.7 3.5e-05 23.3 0.7 1.4 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus PP2C PF00481.21 KFP02952.1 - 2.3e-83 279.8 0.0 2.9e-83 279.4 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.13 KFP02952.1 - 4.8e-31 107.1 0.1 9e-31 106.2 0.1 1.5 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain PP2C_2 PF13672.6 KFP02952.1 - 0.0019 17.9 0.0 0.0056 16.3 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KFP02952.1 - 0.0028 17.6 0.0 2 8.3 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PPR_2 PF13041.6 KFP02953.1 - 1.8e-36 124.1 18.2 6.3e-07 29.5 0.0 14.6 14 1 3 17 17 17 9 PPR repeat family PPR PF01535.20 KFP02953.1 - 2.2e-34 115.3 34.1 0.00093 19.3 0.0 18.3 19 0 0 19 19 19 6 PPR repeat PPR_1 PF12854.7 KFP02953.1 - 1.4e-26 91.9 3.2 7.1e-06 25.6 0.0 10.1 11 0 0 11 11 11 6 PPR repeat PPR_long PF17177.4 KFP02953.1 - 8.6e-26 90.6 10.6 4.8e-07 29.4 0.0 9.0 6 3 3 9 9 9 5 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 KFP02953.1 - 7.5e-23 80.4 15.0 2.5e-07 30.6 0.0 11.3 10 3 5 15 15 15 6 Pentatricopeptide repeat domain TPR_14 PF13428.6 KFP02953.1 - 1.4e-07 31.7 3.2 26 6.0 0.0 9.1 10 1 1 11 11 8 0 Tetratricopeptide repeat ATP13 PF12921.7 KFP02953.1 - 1.8e-05 24.5 0.5 2.8 7.8 0.0 6.7 6 2 1 7 7 7 1 Mitochondrial ATPase expression TPR_16 PF13432.6 KFP02953.1 - 1.9e-05 25.2 0.3 6.1 7.6 0.0 6.2 8 0 0 8 8 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP02953.1 - 2.2e-05 24.9 5.5 10 6.7 0.0 8.2 8 2 2 10 10 9 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFP02953.1 - 0.011 15.9 5.4 13 6.3 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFP02953.1 - 0.026 14.6 0.2 91 3.6 0.1 5.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP02953.1 - 0.053 13.6 0.1 39 4.6 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP02953.1 - 0.11 11.8 0.7 17 4.6 0.0 4.2 5 0 0 5 5 5 0 MalT-like TPR region ANAPC3 PF12895.7 KFP02953.1 - 0.16 12.2 8.9 7.3 6.9 0.3 5.8 5 2 2 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KFP02953.1 - 0.21 11.9 2.4 1.2e+02 3.1 0.0 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat ABC_tran PF00005.27 KFP02954.1 - 2.2e-29 102.7 0.0 3.8e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KFP02954.1 - 8.2e-21 74.4 7.7 1.4e-20 73.7 7.7 1.4 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 KFP02954.1 - 9.8e-07 28.9 0.6 0.02 14.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFP02954.1 - 5.2e-06 27.1 0.0 9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KFP02954.1 - 1.7e-05 24.5 0.2 3.6e-05 23.4 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KFP02954.1 - 5.1e-05 22.8 0.8 0.0029 17.1 0.9 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KFP02954.1 - 0.0062 16.5 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KFP02954.1 - 0.0075 16.7 0.0 0.014 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 KFP02954.1 - 0.018 15.0 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 NTPase DUF5524 PF17662.1 KFP02954.1 - 0.042 13.2 0.0 0.061 12.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5524) NB-ARC PF00931.22 KFP02954.1 - 0.042 13.0 0.0 0.07 12.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.14 KFP02954.1 - 0.075 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.15 KFP02954.1 - 0.091 12.7 0.1 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 KFP02954.1 - 0.091 12.7 0.2 0.23 11.4 0.1 1.8 2 0 0 2 2 2 0 NACHT domain AzlD PF05437.12 KFP02954.1 - 0.94 9.7 6.1 0.21 11.8 2.0 2.1 2 0 0 2 2 1 0 Branched-chain amino acid transport protein (AzlD) DLIC PF05783.11 KFP02955.1 - 9.9e-12 44.4 0.1 4.9e-09 35.6 0.0 2.1 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) Arf PF00025.21 KFP02955.1 - 0.0038 16.7 0.0 0.0079 15.7 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFP02955.1 - 0.0051 16.2 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KFP02955.1 - 0.0056 16.9 0.0 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Elongin_A PF06881.11 KFP02955.1 - 0.41 11.2 3.3 5.2 7.7 1.8 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A MyTH4 PF00784.17 KFP02956.1 - 2e-33 115.1 2.0 2e-33 115.1 2.0 2.6 3 0 0 3 3 3 1 MyTH4 domain PH PF00169.29 KFP02956.1 - 9.4e-28 96.8 0.7 6.2e-19 68.5 0.1 3.9 3 0 0 3 3 3 2 PH domain FERM_M PF00373.18 KFP02956.1 - 4.9e-13 49.5 0.1 4.9e-13 49.5 0.1 2.4 2 0 0 2 2 2 1 FERM central domain PH_8 PF15409.6 KFP02956.1 - 5.8e-07 29.7 0.1 5.1e-05 23.5 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 KFP02956.1 - 2.1e-05 24.9 2.1 2.1e-05 24.9 2.1 4.7 4 1 0 4 4 4 1 Pleckstrin homology domain V_ATPase_I PF01496.19 KFP02956.1 - 4.9 4.9 14.3 9.7 4.0 14.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family 3-HAO PF06052.12 KFP02959.1 - 3.8e-74 247.4 0.1 1.7e-71 238.8 0.3 2.1 2 0 0 2 2 2 2 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KFP02959.1 - 9.4e-13 47.7 0.0 5e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KFP02959.1 - 5.5e-05 22.8 0.1 0.011 15.4 0.1 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KFP02959.1 - 0.0011 18.8 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain MTA_R1 PF17226.2 KFP02960.1 - 6.4e-30 103.1 2.7 1.4e-29 102.0 2.2 1.9 2 0 0 2 2 2 1 MTA R1 domain BAH PF01426.18 KFP02960.1 - 2.5e-27 95.1 4.5 3.6e-27 94.7 1.4 2.4 2 1 0 2 2 2 1 BAH domain ELM2 PF01448.24 KFP02960.1 - 7.4e-17 61.9 0.2 7.4e-17 61.9 0.2 2.8 3 0 0 3 3 3 1 ELM2 domain GATA PF00320.27 KFP02960.1 - 1.2e-09 37.7 8.0 2.8e-09 36.4 8.0 1.7 1 0 0 1 1 1 1 GATA zinc finger Myb_DNA-binding PF00249.31 KFP02960.1 - 4e-06 26.9 0.1 1.8e-05 24.9 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFP02960.1 - 0.01 15.7 0.1 0.027 14.3 0.1 1.7 1 0 0 1 1 1 0 Myb DNA-binding like Herpes_US12 PF05363.12 KFP02960.1 - 0.015 16.0 0.4 0.11 13.2 0.0 2.4 2 0 0 2 2 2 0 Herpesvirus US12 family COX7a PF02238.15 KFP02961.1 - 6.5e-09 36.0 0.0 9.3e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII HELP PF03451.14 KFP02962.1 - 7.3e-31 105.8 0.1 1.7e-30 104.6 0.1 1.7 1 0 0 1 1 1 1 HELP motif WD40 PF00400.32 KFP02962.1 - 1.5e-29 101.6 22.4 0.00038 21.2 0.4 9.7 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP02962.1 - 5.4e-07 29.8 0.1 1.1 9.6 0.0 5.8 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S7 PF00177.21 KFP02962.1 - 0.037 13.7 0.6 0.071 12.8 0.6 1.4 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e Ndc1_Nup PF09531.10 KFP02962.1 - 0.042 12.5 2.8 0.065 11.9 2.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CPSF_A PF03178.15 KFP02962.1 - 0.17 11.2 0.0 2.4 7.4 0.0 2.4 2 1 0 2 2 2 0 CPSF A subunit region PIP49_C PF12260.8 KFP02964.1 - 7.9e-12 45.2 0.0 1.4e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Yae1_N PF09811.9 KFP02965.1 - 2.5e-11 43.1 28.2 0.093 12.5 0.1 3.9 2 1 0 2 2 2 2 Essential protein Yae1, N terminal GLTSCR1 PF15249.6 KFP02967.1 - 1.3e-32 112.3 1.3 4.1e-32 110.6 1.3 2.0 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein Tetraspanin PF00335.20 KFP02969.1 - 4.7e-28 98.5 5.0 6.3e-28 98.0 5.0 1.1 1 0 0 1 1 1 1 Tetraspanin family ClpS PF02617.17 KFP02970.1 - 8.3e-23 80.0 0.5 2.2e-22 78.6 0.5 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-UBR PF02207.20 KFP02970.1 - 6.5e-21 74.3 8.9 6.5e-21 74.3 8.9 2.6 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) zf-C2H2_6 PF13912.6 KFP02971.1 - 9.1e-18 63.8 6.0 4.5e-07 29.7 0.3 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KFP02971.1 - 2.7e-10 40.2 7.7 0.03 15.1 0.2 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP02971.1 - 1e-08 35.1 8.2 0.047 14.2 1.2 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type ELM2 PF01448.24 KFP02971.1 - 1.5e-07 32.0 0.0 1.5e-07 32.0 0.0 2.8 3 0 0 3 3 3 1 ELM2 domain Myb_DNA-binding PF00249.31 KFP02971.1 - 3.9e-05 23.8 0.2 8.5e-05 22.7 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C2H2_jaz PF12171.8 KFP02971.1 - 0.0013 19.0 0.8 2.6 8.4 0.3 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP02971.1 - 0.0022 18.3 5.2 0.094 13.1 0.2 4.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFP02971.1 - 0.012 15.9 0.0 0.012 15.9 0.0 4.1 4 1 0 4 4 4 0 C2H2 type zinc-finger (2 copies) Myb_DNA-bind_7 PF15963.5 KFP02971.1 - 0.012 15.5 0.2 0.012 15.5 0.2 2.4 2 0 0 2 2 2 0 Myb DNA-binding like Ribosomal_S10 PF00338.22 KFP02972.1 - 4.1e-26 91.1 0.1 5.7e-26 90.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e UTP25 PF06862.12 KFP02973.1 - 2.3e-191 636.7 6.5 3e-191 636.3 6.5 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 KFP02973.1 - 0.0017 18.2 0.0 0.3 10.8 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase C2 PF00168.30 KFP02974.1 - 2.5e-21 75.9 0.1 1.7e-13 50.7 0.0 2.2 2 0 0 2 2 2 2 C2 domain Bcr-Abl_Oligo PF09036.10 KFP02974.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain SERTA PF06031.13 KFP02975.1 - 1.7e-15 56.4 0.1 2.9e-15 55.6 0.1 1.4 1 0 0 1 1 1 1 SERTA motif MBOAT PF03062.19 KFP02976.1 - 3.5e-42 145.0 24.6 4.9e-42 144.5 24.6 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Ion_trans PF00520.31 KFP02977.1 - 7.5e-36 123.6 8.7 1e-35 123.1 8.7 1.2 1 0 0 1 1 1 1 Ion transport protein PAS_9 PF13426.7 KFP02977.1 - 5.1e-18 65.2 0.1 1.4e-17 63.9 0.1 1.7 1 0 0 1 1 1 1 PAS domain cNMP_binding PF00027.29 KFP02977.1 - 1.7e-14 53.6 0.0 4.5e-14 52.3 0.0 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KFP02977.1 - 5e-12 45.6 3.0 5e-12 45.6 3.0 2.0 2 0 0 2 2 2 1 Ion channel PAS PF00989.25 KFP02977.1 - 1e-06 28.7 0.1 4.6e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 KFP02977.1 - 3e-05 24.2 0.0 8.7e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 PAS fold Cupin_3 PF05899.12 KFP02977.1 - 0.013 15.1 0.1 0.041 13.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF861) PAS_4 PF08448.10 KFP02977.1 - 0.026 14.8 0.0 0.057 13.7 0.0 1.6 1 0 0 1 1 1 0 PAS fold Cupin_2 PF07883.11 KFP02977.1 - 0.03 14.0 0.1 0.075 12.8 0.1 1.6 1 0 0 1 1 1 0 Cupin domain Myb_DNA-binding PF00249.31 KFP02978.1 - 4.6e-19 68.3 0.0 1.5e-10 41.1 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFP02978.1 - 1.6e-08 34.3 3.7 0.00073 19.4 0.1 3.2 2 1 1 3 3 3 2 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 KFP02978.1 - 4.3e-06 26.9 3.2 0.0018 18.5 0.1 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain ELM2 PF01448.24 KFP02978.1 - 0.00012 22.7 0.2 0.00064 20.4 0.0 2.4 2 0 0 2 2 2 1 ELM2 domain zf-TRAF PF02176.18 KFP02979.1 - 1.9e-23 82.9 24.1 2.2e-14 53.9 6.5 4.0 3 1 1 4 4 3 2 TRAF-type zinc finger zf-TRAF_2 PF15965.5 KFP02979.1 - 1.2e-07 32.1 35.3 1.8e-07 31.5 10.0 3.5 3 1 1 4 4 2 2 TRAF-like zinc-finger zf-ACC PF17848.1 KFP02979.1 - 9.1e-07 28.8 4.9 0.0004 20.4 0.2 3.9 3 0 0 3 3 3 2 Acetyl-coA carboxylase zinc finger domain zf-C3HC4_2 PF13923.6 KFP02979.1 - 1.1e-05 25.2 7.0 1.1e-05 25.2 7.0 4.3 5 1 0 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP02979.1 - 1.6e-05 24.6 6.0 1.6e-05 24.6 6.0 4.6 4 1 1 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFP02979.1 - 0.00025 21.1 5.2 0.00025 21.1 5.2 3.5 4 0 0 4 4 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KFP02979.1 - 0.00091 19.2 5.5 0.00091 19.2 5.5 3.7 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP02979.1 - 0.0018 18.2 6.2 0.0018 18.2 6.2 4.4 3 1 1 4 4 2 1 zinc-RING finger domain DUF4941 PF16299.5 KFP02979.1 - 0.003 16.9 0.8 0.0051 16.2 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4941) zf-RING_2 PF13639.6 KFP02979.1 - 0.022 15.1 6.2 0.022 15.1 6.2 3.8 3 1 1 4 4 3 0 Ring finger domain Coat_F PF07875.12 KFP02979.1 - 0.084 13.1 3.4 6.6 7.1 0.2 2.8 2 0 0 2 2 2 0 Coat F domain DUF4279 PF14106.6 KFP02979.1 - 0.23 11.7 3.7 4.5 7.5 3.6 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4279) Med4 PF10018.9 KFP02979.1 - 1.4 8.6 8.7 1.5 8.4 7.2 1.8 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Tropomyosin_1 PF12718.7 KFP02979.1 - 2 8.6 11.6 5.3 7.2 11.6 1.8 1 1 0 1 1 1 0 Tropomyosin like DUF4795 PF16043.5 KFP02979.1 - 3.2 7.3 18.2 11 5.6 18.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) zf-RING_6 PF14835.6 KFP02979.1 - 4.7 7.2 14.4 0.027 14.3 2.9 3.2 2 1 0 3 3 3 0 zf-RING of BARD1-type protein RD3 PF14473.6 KFP02980.1 - 4.1e-48 162.5 2.1 5.7e-48 162.1 2.1 1.2 1 0 0 1 1 1 1 RD3 protein CALCOCO1 PF07888.11 KFP02980.1 - 0.0095 14.9 0.5 0.0095 14.9 0.5 1.7 2 0 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like Cation_efflux PF01545.21 KFP02981.1 - 4e-09 36.5 0.2 0.0024 17.6 0.7 2.1 2 0 0 2 2 2 2 Cation efflux family Pkinase PF00069.25 KFP02982.1 - 5.6e-55 186.6 1.0 3e-54 184.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP02982.1 - 1.6e-39 135.8 1.6 5.8e-39 133.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP02982.1 - 6.6e-06 25.7 0.0 1.3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFP02982.1 - 0.0088 16.0 2.1 0.26 11.2 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Exonuc_VII_L PF02601.15 KFP02982.1 - 1.3 8.5 4.4 1.8 8.1 4.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3552 PF12072.8 KFP02982.1 - 1.3 8.4 16.9 0.035 13.5 10.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Acyltransf_C PF16076.5 KFP02983.1 - 2.4e-16 59.6 0.0 6e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 KFP02983.1 - 1.9e-07 30.8 0.1 3.1e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 Acyltransferase HEAT_2 PF13646.6 KFP02984.1 - 0.00015 22.1 2.9 0.25 11.8 0.1 4.7 4 0 0 4 4 4 1 HEAT repeats TPR_6 PF13174.6 KFP02984.1 - 0.0044 17.6 1.4 2.2 9.1 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Paz_1 PF18349.1 KFP02984.1 - 0.012 15.5 0.0 0.68 9.9 0.0 2.4 2 0 0 2 2 2 0 PAZ domain DUF3453 PF11935.8 KFP02984.1 - 0.029 14.0 5.6 0.058 13.0 0.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3453) Spindle_Spc25 PF08234.12 KFP02984.1 - 0.079 13.2 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 TPR_2 PF07719.17 KFP02984.1 - 0.21 11.8 0.5 12 6.4 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat SPG48 PF14764.6 KFP02984.1 - 0.45 11.0 5.8 0.32 11.5 0.2 3.7 3 2 0 3 3 3 0 AP-5 complex subunit, vesicle trafficking FANCI_S2 PF14676.6 KFP02984.1 - 2.1 8.6 9.9 2.5 8.4 2.0 2.9 3 0 0 3 3 3 0 FANCI solenoid 2 WD40 PF00400.32 KFP02985.1 - 1.2e-20 73.4 8.4 0.00026 21.7 0.1 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP02985.1 - 0.00014 22.1 0.1 0.039 14.3 0.1 3.5 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain B56 PF01603.20 KFP02986.1 - 3.9e-191 635.5 11.2 4.6e-191 635.3 11.2 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KFP02986.1 - 0.036 14.0 2.5 1 9.2 0.2 3.3 2 1 1 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal TMEM206 PF15122.6 KFP02987.1 - 1.1e-171 569.7 2.3 1.3e-171 569.5 2.3 1.0 1 0 0 1 1 1 1 TMEM206 protein family Tetraspanin PF00335.20 KFP02987.1 - 0.019 14.7 0.2 0.059 13.1 0.0 1.8 2 0 0 2 2 2 0 Tetraspanin family OppC_N PF12911.7 KFP02987.1 - 1.8 8.6 4.0 5.4 7.1 0.4 2.7 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Cyt-b5 PF00173.28 KFP02988.1 - 8.6e-11 41.8 0.0 1.1e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain bZIP_1 PF00170.21 KFP02989.1 - 7.8e-12 45.1 18.2 1.4e-11 44.3 18.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFP02989.1 - 1.1e-09 38.2 19.2 1.7e-09 37.6 19.2 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFP02989.1 - 9.3e-08 32.5 7.9 9.3e-08 32.5 7.9 1.6 2 0 0 2 2 2 1 bZIP Maf transcription factor Dapper PF15268.6 KFP02989.1 - 0.0057 15.6 2.0 0.0059 15.5 2.0 1.0 1 0 0 1 1 1 1 Dapper APG6_N PF17675.1 KFP02989.1 - 0.0065 17.0 8.7 0.01 16.4 8.7 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region FemAB PF02388.16 KFP02989.1 - 0.018 14.0 1.4 0.022 13.7 1.4 1.1 1 0 0 1 1 1 0 FemAB family Ribosomal_L6e PF01159.19 KFP02989.1 - 0.058 13.9 6.7 0.13 12.8 6.5 1.6 1 1 1 2 2 2 0 Ribosomal protein L6e Afi1 PF07792.12 KFP02989.1 - 0.074 13.5 2.8 0.11 13.0 2.8 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DivIC PF04977.15 KFP02989.1 - 0.3 10.9 7.5 0.41 10.4 6.7 1.7 2 0 0 2 2 2 0 Septum formation initiator Macoilin PF09726.9 KFP02989.1 - 1.1 7.7 10.8 1.4 7.4 10.8 1.1 1 0 0 1 1 1 0 Macoilin family Fungal_TACC PF12709.7 KFP02989.1 - 1.6 9.2 9.9 0.97 9.9 7.7 1.7 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Mis14 PF08641.12 KFP02990.1 - 9.9e-21 74.4 0.7 2.2e-20 73.3 0.7 1.6 1 1 0 1 1 1 1 Kinetochore protein Mis14 like TatD_DNase PF01026.21 KFP02991.1 - 2.2e-48 164.9 0.1 5.3e-48 163.6 0.1 1.5 1 1 0 1 1 1 1 TatD related DNase Flexi_CP_N PF08358.10 KFP02991.1 - 0.012 15.5 0.1 0.043 13.8 0.0 1.9 2 0 0 2 2 2 0 Carlavirus coat MFS_1 PF07690.16 KFP02992.1 - 6.4e-28 97.7 33.3 6.4e-28 97.7 33.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily UL45 PF05473.12 KFP02992.1 - 5.9 6.5 6.4 1.8 8.2 0.1 2.9 3 1 0 3 3 3 0 UL45 protein, carbohydrate-binding C-type lectin-like Exo_endo_phos PF03372.23 KFP02993.1 - 1.7e-24 86.7 0.0 2.2e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KFP02993.1 - 0.02 14.8 1.4 0.11 12.3 0.0 2.8 4 0 0 4 4 4 0 Endonuclease-reverse transcriptase Pkinase PF00069.25 KFP02994.1 - 1.4e-28 100.0 0.0 5.1e-25 88.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain MIT PF04212.18 KFP02994.1 - 3.5e-18 65.4 1.4 6.6e-18 64.5 1.4 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain PX PF00787.24 KFP02994.1 - 2.6e-12 46.7 0.3 4.9e-12 45.8 0.3 1.5 1 0 0 1 1 1 1 PX domain Pkinase_Tyr PF07714.17 KFP02994.1 - 3e-11 43.1 0.0 1.7e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP02994.1 - 1.5e-05 24.5 0.0 2.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KFP02994.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 USP8_dimer PF08969.11 KFP02994.1 - 0.13 12.4 0.1 0.36 11.0 0.1 1.7 1 0 0 1 1 1 0 USP8 dimerisation domain APH PF01636.23 KFP02994.1 - 0.15 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KFP02994.1 - 0.16 11.3 0.1 0.3 10.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HPD PF05044.12 KFP02995.1 - 1.5e-83 278.2 2.8 2.8e-83 277.4 2.8 1.4 1 0 0 1 1 1 1 Homeo-prospero domain NifQ PF04891.12 KFP02995.1 - 0.015 15.7 3.5 0.47 10.8 0.0 3.4 3 0 0 3 3 3 0 NifQ MCU PF04678.13 KFP02995.1 - 0.15 12.1 1.4 0.32 11.1 1.4 1.6 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Metal_resist PF13801.6 KFP02995.1 - 0.22 11.7 9.8 0.3 11.3 8.1 2.1 2 0 0 2 2 2 0 Heavy-metal resistance FliD_N PF02465.18 KFP02995.1 - 0.23 12.2 4.2 7 7.4 5.5 2.8 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus AATF-Che1 PF13339.6 KFP02995.1 - 0.46 11.2 9.5 2 9.1 9.4 2.2 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor Exonuc_VII_L PF02601.15 KFP02995.1 - 0.73 9.3 6.2 1.4 8.4 6.2 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 KFP02995.1 - 1.1 7.8 3.9 1.6 7.2 3.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2968 PF11180.8 KFP02995.1 - 1.2 8.7 15.8 2.4 7.8 15.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) WDCP PF15390.6 KFP02995.1 - 1.8 6.8 8.8 2.8 6.2 8.8 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family PP_kinase_N PF13089.6 KFP02995.1 - 1.9 8.8 10.2 3 8.2 4.7 3.3 2 1 1 3 3 3 0 Polyphosphate kinase N-terminal domain Nop25 PF09805.9 KFP02995.1 - 2.3 8.7 18.5 5 7.6 18.5 1.6 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF4407 PF14362.6 KFP02995.1 - 5.6 6.2 8.4 8.8 5.6 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SET PF00856.28 KFP02996.1 - 8.8e-12 45.7 0.1 2e-11 44.6 0.1 1.6 1 0 0 1 1 1 1 SET domain TPR_12 PF13424.6 KFP02996.1 - 1.3e-05 25.4 0.0 0.0015 18.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFP02996.1 - 0.00092 19.3 0.1 0.0026 17.8 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFP02996.1 - 0.0017 18.2 0.0 0.0067 16.3 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFP02996.1 - 0.026 14.6 0.2 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFP02996.1 - 0.092 13.6 0.1 0.54 11.2 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat CENP-F_N PF10481.9 KFP02997.1 - 8.8e-70 235.8 26.9 9.8e-70 235.6 26.9 1.0 1 0 0 1 1 1 1 Cenp-F N-terminal domain Fez1 PF06818.15 KFP02997.1 - 0.00028 21.4 19.2 0.00034 21.1 19.2 1.0 1 0 0 1 1 1 1 Fez1 Spc7 PF08317.11 KFP02997.1 - 0.0022 16.9 22.0 0.0025 16.8 22.0 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein ATG16 PF08614.11 KFP02997.1 - 0.017 15.4 23.7 0.085 13.1 23.5 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF2514 PF10721.9 KFP02997.1 - 0.024 14.7 2.7 0.024 14.6 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) TPR_MLP1_2 PF07926.12 KFP02997.1 - 0.031 14.3 25.0 0.15 12.1 11.1 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein GrpE PF01025.19 KFP02997.1 - 0.052 13.2 18.3 0.12 12.0 18.3 1.6 1 1 0 1 1 1 0 GrpE RACo_linker PF17650.1 KFP02997.1 - 0.066 13.1 1.6 0.38 10.6 0.1 2.5 1 1 0 2 2 2 0 RACo linker region OmpH PF03938.14 KFP02997.1 - 0.076 13.3 24.6 0.23 11.8 24.6 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) PuR_N PF09182.10 KFP02997.1 - 0.084 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal V_ATPase_I PF01496.19 KFP02997.1 - 0.087 10.7 13.2 0.094 10.6 13.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FUSC PF04632.12 KFP02997.1 - 0.093 11.2 4.5 0.097 11.2 4.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family HIP1_clath_bdg PF16515.5 KFP02997.1 - 0.1 13.3 22.6 0.11 13.1 10.8 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FlaC_arch PF05377.11 KFP02997.1 - 0.14 12.6 16.1 1.2 9.6 1.4 3.2 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) CREPT PF16566.5 KFP02997.1 - 0.17 12.0 14.2 0.064 13.4 11.3 1.6 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour ADIP PF11559.8 KFP02997.1 - 0.28 11.3 25.8 0.055 13.6 14.3 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Prominin PF05478.11 KFP02997.1 - 0.35 8.8 9.9 0.48 8.3 9.9 1.2 1 0 0 1 1 1 0 Prominin UPF0242 PF06785.11 KFP02997.1 - 0.38 10.8 20.7 0.51 10.4 20.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 KFP02997.1 - 0.45 10.0 14.7 0.51 9.9 14.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit APG6_N PF17675.1 KFP02997.1 - 0.46 11.0 25.2 2.7 8.5 25.2 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region Calici_MSP PF05752.11 KFP02997.1 - 0.47 10.2 3.9 0.56 10.0 3.3 1.5 1 1 1 2 2 2 0 Calicivirus minor structural protein DUF4407 PF14362.6 KFP02997.1 - 0.48 9.7 12.2 0.55 9.5 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 KFP02997.1 - 0.49 8.9 14.3 0.57 8.7 14.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF848 PF05852.11 KFP02997.1 - 0.67 10.1 12.4 1.1 9.3 11.5 1.7 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) PHM7_cyt PF14703.6 KFP02997.1 - 0.71 10.1 8.6 0.97 9.6 8.6 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter YlqD PF11068.8 KFP02997.1 - 0.89 9.9 23.2 0.65 10.4 13.5 2.1 1 1 1 2 2 2 0 YlqD protein Bacillus_HBL PF05791.11 KFP02997.1 - 1.2 9.0 15.2 0.46 10.3 8.8 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) UPF0231 PF06062.11 KFP02997.1 - 1.3 9.3 12.0 1.9 8.8 6.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0231) Macoilin PF09726.9 KFP02997.1 - 1.4 7.4 16.6 1.7 7.1 16.6 1.1 1 0 0 1 1 1 0 Macoilin family COG2 PF06148.11 KFP02997.1 - 2.3 8.3 14.1 1.1 9.3 8.7 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 5_nucleotid PF05761.14 KFP02997.1 - 2.3 7.0 10.6 2.5 6.9 10.6 1.1 1 0 0 1 1 1 0 5' nucleotidase family DUF2205 PF10224.9 KFP02997.1 - 3 7.9 16.2 1 9.4 11.1 2.4 1 1 0 2 2 2 0 Short coiled-coil protein CENP-H PF05837.12 KFP02997.1 - 3.5 8.1 21.6 4.7 7.7 19.3 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Fib_alpha PF08702.10 KFP02997.1 - 3.6 7.8 17.0 5.8 7.1 17.0 1.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family End3 PF12761.7 KFP02997.1 - 3.8 7.6 20.2 6.2 6.9 20.2 1.4 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 YabA PF06156.13 KFP02997.1 - 4 8.1 16.7 9.9 6.9 12.5 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Cdh1_DBD_1 PF18196.1 KFP02997.1 - 4.1 7.7 13.1 2 8.7 9.5 1.9 1 1 1 2 2 2 0 Chromodomain helicase DNA-binding domain 1 DUF3552 PF12072.8 KFP02997.1 - 4.5 6.6 26.6 3.5 7.0 17.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DivIC PF04977.15 KFP02997.1 - 5.6 6.8 26.4 4.6 7.1 7.4 3.1 1 1 2 3 3 3 0 Septum formation initiator DUF641 PF04859.12 KFP02997.1 - 5.7 7.3 17.4 19 5.6 5.9 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) SpecificRecomb PF10136.9 KFP02997.1 - 5.8 5.1 7.1 7 4.8 7.1 1.0 1 0 0 1 1 1 0 Site-specific recombinase HemX PF04375.14 KFP02997.1 - 8.1 5.6 23.6 11 5.2 12.2 2.0 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Spc24 PF08286.11 KFP02997.1 - 8.9 6.6 20.8 15 5.9 10.9 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Filament PF00038.21 KFP02998.1 - 0.0038 16.9 13.1 0.027 14.1 13.1 1.8 1 1 0 1 1 1 1 Intermediate filament protein FliJ PF02050.16 KFP02998.1 - 0.0056 16.9 10.2 0.018 15.3 9.7 1.8 1 1 0 1 1 1 1 Flagellar FliJ protein KBP_C PF12309.8 KFP02998.1 - 0.0099 15.4 5.4 0.012 15.2 5.4 1.2 1 0 0 1 1 1 1 KIF-1 binding protein C terminal Baculo_PEP_C PF04513.12 KFP02998.1 - 0.015 15.3 7.0 0.042 13.9 7.0 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lebercilin PF15619.6 KFP02998.1 - 0.022 14.5 19.6 0.53 9.9 2.5 2.0 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease SlyX PF04102.12 KFP02998.1 - 0.03 14.9 1.0 0.03 14.9 1.0 2.1 1 1 1 2 2 2 0 SlyX FlaC_arch PF05377.11 KFP02998.1 - 0.045 14.1 1.4 0.045 14.1 1.4 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) ApoLp-III PF07464.11 KFP02998.1 - 0.093 12.8 11.1 0.17 12.0 5.0 2.0 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) TetR_C_37 PF18665.1 KFP02998.1 - 0.1 13.2 4.8 0.16 12.6 4.6 1.4 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Spc7 PF08317.11 KFP02998.1 - 0.1 11.4 17.9 0.18 10.6 17.9 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 KFP02998.1 - 0.12 12.7 11.0 0.1 12.9 6.1 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF641 PF04859.12 KFP02998.1 - 0.13 12.6 14.9 0.15 12.4 6.9 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Apolipoprotein PF01442.18 KFP02998.1 - 0.13 12.1 11.3 1.9 8.3 11.2 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Spectrin PF00435.21 KFP02998.1 - 0.18 12.3 13.4 0.18 12.3 5.9 2.0 1 1 1 2 2 2 0 Spectrin repeat MIP-T3_C PF17749.1 KFP02998.1 - 0.22 11.5 11.4 2.7 7.9 11.3 2.1 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region CREPT PF16566.5 KFP02998.1 - 0.26 11.4 13.7 0.63 10.2 4.5 2.1 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour CENP-F_leu_zip PF10473.9 KFP02998.1 - 0.27 11.2 20.2 1.1 9.3 20.4 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HIP1_clath_bdg PF16515.5 KFP02998.1 - 0.31 11.7 17.6 2.5 8.8 8.1 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Uso1_p115_C PF04871.13 KFP02998.1 - 0.35 11.2 15.0 0.65 10.4 15.0 1.5 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4763 PF15960.5 KFP02998.1 - 0.44 9.8 14.8 0.53 9.6 14.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Syntaxin-6_N PF09177.11 KFP02998.1 - 0.44 11.1 10.2 5.3 7.7 9.4 2.1 1 1 0 1 1 1 0 Syntaxin 6, N-terminal ApoO PF09769.9 KFP02998.1 - 0.45 10.5 3.8 0.54 10.2 1.2 1.9 1 1 1 2 2 2 0 Apolipoprotein O DUF1664 PF07889.12 KFP02998.1 - 0.55 10.3 9.6 1.7 8.7 9.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 KFP02998.1 - 0.59 9.9 13.0 0.73 9.6 13.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Fib_alpha PF08702.10 KFP02998.1 - 0.73 10.0 13.7 0.14 12.4 5.9 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 KFP02998.1 - 0.87 8.8 12.0 1 8.5 12.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Exonuc_VII_L PF02601.15 KFP02998.1 - 1 8.8 9.1 1.1 8.7 9.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 KFP02998.1 - 1.1 7.1 9.0 1.2 6.9 9.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.14 KFP02998.1 - 1.2 9.5 14.8 1.9 8.8 14.8 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3450 PF11932.8 KFP02998.1 - 1.2 8.4 12.5 3.4 6.9 12.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) P4Ha_N PF08336.11 KFP02998.1 - 1.3 9.0 12.4 1.1 9.3 5.3 2.3 1 1 2 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF948 PF06103.11 KFP02998.1 - 1.5 9.1 6.7 3.7 7.9 2.0 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Mt_ATP-synt_D PF05873.12 KFP02998.1 - 1.6 8.6 10.4 1.2 8.9 3.5 2.2 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) UPF0242 PF06785.11 KFP02998.1 - 1.7 8.7 18.8 1.6 8.8 10.0 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 KFP02998.1 - 1.7 9.2 19.4 4.8 7.7 17.5 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 KFP02998.1 - 1.8 8.8 16.8 11 6.4 7.9 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FapA PF03961.13 KFP02998.1 - 1.9 7.0 13.1 2.3 6.7 13.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A FliD_N PF02465.18 KFP02998.1 - 3.1 8.5 9.0 0.67 10.7 3.4 2.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Nas2_N PF18265.1 KFP02998.1 - 3.5 7.6 8.4 6 6.9 1.0 2.7 2 1 0 2 2 2 0 Nas2 N_terminal domain DUF2203 PF09969.9 KFP02998.1 - 3.7 8.3 8.4 2.3 8.9 4.6 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Cnn_1N PF07989.11 KFP02998.1 - 3.8 7.7 19.9 2.4 8.4 3.1 3.1 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 Prefoldin PF02996.17 KFP02998.1 - 5.5 6.9 14.9 4.6 7.2 2.1 2.9 1 1 0 2 2 2 0 Prefoldin subunit H-kinase_dim PF02895.14 KFP02998.1 - 6.2 7.3 8.8 3.5e+02 1.7 8.8 2.6 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain ArlS_N PF18719.1 KFP02998.1 - 6.6 7.0 11.8 17 5.6 8.6 2.0 1 1 1 2 2 2 0 ArlS sensor domain DUF2730 PF10805.8 KFP02998.1 - 6.8 6.9 10.1 2.2 8.4 4.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) CCDC-167 PF15188.6 KFP02998.1 - 7.6 7.0 17.4 1.5 9.2 4.4 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF16 PF01519.16 KFP02998.1 - 7.7 7.1 13.0 31 5.1 13.0 1.8 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF4407 PF14362.6 KFP02998.1 - 7.8 5.8 10.2 13 5.0 10.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ACCA PF03255.14 KFP02998.1 - 10 6.0 12.7 5.3 6.9 4.1 2.0 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit CENP-F_C_Rb_bdg PF10490.9 KFP02999.1 - 1.1e-05 24.8 0.3 2.2e-05 23.8 0.1 1.7 2 0 0 2 2 2 1 Rb-binding domain of kinetochore protein Cenp-F/LEK1 DUF87 PF01935.17 KFP02999.1 - 0.21 11.6 2.4 0.29 11.2 2.4 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain Trehalase_Ca-bi PF07492.11 KFP02999.1 - 0.78 9.5 4.0 0.25 11.1 0.7 1.9 2 0 0 2 2 2 0 Neutral trehalase Ca2+ binding domain V_ATPase_I PF01496.19 KFP02999.1 - 4.8 5.0 7.1 5.1 4.9 7.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ion_trans_2 PF07885.16 KFP03000.1 - 2.6e-37 126.7 29.5 7.8e-20 70.6 10.9 4.0 3 1 1 4 4 4 3 Ion channel bZIP_Maf PF03131.17 KFP03000.1 - 0.0065 17.0 0.5 0.013 16.0 0.5 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Hormone_recep PF00104.30 KFP03001.1 - 1.9e-32 112.6 0.4 2.9e-32 112.0 0.4 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFP03001.1 - 6.6e-31 106.6 12.3 1.3e-30 105.7 12.3 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) GAT PF03127.14 KFP03001.1 - 0.19 12.0 2.1 0.6 10.5 0.3 2.4 2 0 0 2 2 2 0 GAT domain G-patch PF01585.23 KFP03002.1 - 4.1e-16 58.6 1.9 8.4e-16 57.6 1.9 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFP03002.1 - 1.7e-08 34.4 0.5 1.7e-08 34.4 0.5 2.5 3 0 0 3 3 3 1 G-patch domain IQ PF00612.27 KFP03003.1 - 1.3e-13 49.4 22.7 7.6e-05 22.2 1.6 3.8 3 0 0 3 3 3 3 IQ calmodulin-binding motif Rrp15p PF07890.12 KFP03004.1 - 2.2e-34 118.7 14.0 3.8e-34 117.9 14.0 1.4 1 0 0 1 1 1 1 Rrp15p Baseplate_J PF04865.14 KFP03004.1 - 0.019 14.1 0.1 0.029 13.5 0.1 1.2 1 0 0 1 1 1 0 Baseplate J-like protein TGFb_propeptide PF00688.18 KFP03005.1 - 2.3e-36 125.8 0.0 3e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 KFP03005.1 - 5.1e-24 85.2 1.3 1.4e-23 83.8 1.3 1.8 1 0 0 1 1 1 1 Transforming growth factor beta like domain SPEG_u2 PF16650.5 KFP03005.1 - 0.76 10.0 4.4 0.16 12.1 0.5 1.8 2 0 0 2 2 2 0 Unstructured region on SPEG complex protein Abhydrolase_2 PF02230.16 KFP03006.1 - 5.7e-36 124.4 0.0 6.7e-36 124.1 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KFP03006.1 - 2.4e-06 27.6 0.0 0.00045 20.1 0.0 2.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFP03006.1 - 3.7e-05 23.1 0.0 0.0014 18.0 0.0 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFP03006.1 - 4.8e-05 22.9 0.3 0.0058 16.1 0.3 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KFP03006.1 - 0.0012 18.5 0.1 0.0039 16.9 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KFP03006.1 - 0.0015 18.3 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KFP03006.1 - 0.0022 17.6 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 KFP03006.1 - 0.0065 16.1 0.0 0.0065 16.1 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 KFP03006.1 - 0.013 15.6 0.0 0.028 14.5 0.0 1.6 1 1 0 1 1 1 0 Thioesterase domain Abhydrolase_6 PF12697.7 KFP03006.1 - 0.016 15.8 0.0 0.02 15.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 KFP03006.1 - 0.024 14.5 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Yae1_N PF09811.9 KFP03008.1 - 1.2e-15 56.9 65.2 1.8e+04 -28.7 65.2 5.9 1 1 0 1 1 1 0 Essential protein Yae1, N terminal HMG_box PF00505.19 KFP03010.1 - 8.7e-27 93.3 2.5 8.8e-26 90.1 3.5 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP03010.1 - 1.5e-08 35.1 0.6 3e-08 34.1 0.6 1.5 1 0 0 1 1 1 1 HMG-box domain Roughex PF06020.11 KFP03010.1 - 0.21 10.6 2.0 0.43 9.6 2.0 1.5 1 0 0 1 1 1 0 Drosophila roughex protein Thymidylate_kin PF02223.17 KFP03011.1 - 8.7e-10 38.6 0.1 5.6e-09 35.9 0.1 2.1 1 1 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.6 KFP03011.1 - 0.00085 19.5 0.0 0.0011 19.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain PPK2 PF03976.14 KFP03011.1 - 0.018 14.6 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) AAA_16 PF13191.6 KFP03011.1 - 0.022 15.2 0.0 0.029 14.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain 6PF2K PF01591.18 KFP03011.1 - 0.11 11.8 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Arf PF00025.21 KFP03011.1 - 0.16 11.4 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family TniB PF05621.11 KFP03011.1 - 0.17 11.2 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein Radical_SAM PF04055.21 KFP03012.1 - 5.1e-15 56.2 0.0 1.5e-14 54.7 0.0 1.8 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 KFP03012.1 - 2.8e-08 33.9 0.6 4.6e-07 30.0 0.1 2.2 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 KFP03012.1 - 3.8e-08 33.7 0.2 7.2e-08 32.8 0.2 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain IBR PF01485.21 KFP03013.1 - 7.8e-20 70.9 26.8 4.2e-13 49.3 11.4 4.6 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KFP03013.1 - 0.022 15.1 7.0 0.022 15.1 7.0 4.9 4 2 1 5 5 5 0 Ring finger domain Histone PF00125.24 KFP03014.1 - 6.4e-26 91.3 0.3 7.8e-26 91.0 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFP03014.1 - 9.4e-07 29.0 0.7 1.8e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KFP03014.1 - 0.0034 17.8 0.0 0.006 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KFP03014.1 - 0.0059 16.7 0.2 0.0067 16.5 0.2 1.1 1 0 0 1 1 1 1 YscO-like protein AMP-binding PF00501.28 KFP03015.1 - 1.7e-09 36.8 0.0 2.2e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFP03015.1 - 0.0041 18.1 0.3 0.0066 17.4 0.3 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LRR_9 PF14580.6 KFP03016.1 - 6.6e-26 90.9 18.0 9.3e-16 57.8 3.6 3.8 2 1 1 3 3 3 3 Leucine-rich repeat LRR_4 PF12799.7 KFP03016.1 - 9e-20 70.5 42.1 4.7e-08 33.2 5.9 5.6 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP03016.1 - 1.7e-11 43.7 41.3 2.4e-05 24.0 6.1 6.6 5 1 0 7 7 7 4 Leucine rich repeat DUF2322 PF10084.9 KFP03016.1 - 0.98 9.5 3.6 8.8 6.4 0.2 3.5 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2322) LRR_3 PF07725.12 KFP03016.1 - 3.1 7.8 6.2 36 4.4 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich Repeat DUF4413 PF14372.6 KFP03016.1 - 5.1 7.5 7.4 1 9.7 1.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) LRR_6 PF13516.6 KFP03016.1 - 9.9 6.5 17.1 2.6 8.3 0.2 5.7 5 0 0 5 5 5 0 Leucine Rich repeat La PF05383.17 KFP03017.1 - 6e-22 77.5 0.2 1.8e-21 75.9 0.2 1.8 1 0 0 1 1 1 1 La domain AbiEi_2 PF09952.9 KFP03017.1 - 0.075 13.3 0.2 0.11 12.7 0.2 1.2 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system A_deaminase PF00962.22 KFP03018.1 - 1.6e-35 123.0 0.0 1.8e-35 122.8 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 KFP03018.1 - 0.013 14.8 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase family TM2 PF05154.16 KFP03019.1 - 8.6e-15 54.8 7.9 1.4e-14 54.1 7.9 1.3 1 0 0 1 1 1 1 TM2 domain tRNA-synt_2b PF00587.25 KFP03020.1 - 6.3e-35 120.7 0.0 1e-34 120.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KFP03020.1 - 7.6e-20 70.9 0.1 1.8e-19 69.7 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 KFP03020.1 - 3.4e-13 49.5 0.1 7.7e-13 48.3 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 KFP03020.1 - 2.9e-12 46.4 0.0 5.1e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 TGS domain PDZ PF00595.24 KFP03021.1 - 1.1e-46 157.0 7.2 3.5e-15 56.1 0.1 3.5 3 0 0 3 3 3 3 PDZ domain ZU5 PF00791.20 KFP03021.1 - 1.9e-36 124.3 0.0 6e-36 122.7 0.0 1.9 1 0 0 1 1 1 1 ZU5 domain PDZ_6 PF17820.1 KFP03021.1 - 2.6e-24 84.8 2.4 3.7e-09 36.3 0.1 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 KFP03021.1 - 3.5e-16 59.3 3.8 8.3e-05 22.8 0.1 3.6 3 0 0 3 3 3 3 PDZ domain Guanylate_kin PF00625.21 KFP03021.1 - 3.3e-12 46.5 0.0 6.1e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.17 KFP03021.1 - 4.7e-11 42.2 0.1 1.2e-10 40.9 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP03021.1 - 0.0026 17.3 0.1 0.021 14.4 0.0 2.5 2 0 0 2 2 2 1 SH3 domain RPOL_N PF14700.6 KFP03021.1 - 0.057 12.8 2.0 0.35 10.2 0.1 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal CD20 PF04103.15 KFP03022.1 - 8e-19 68.3 12.1 1.7e-18 67.2 12.1 1.6 1 0 0 1 1 1 1 CD20-like family PID PF00640.23 KFP03023.1 - 6e-52 175.4 5.4 1.6e-51 174.0 2.3 2.4 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.24 KFP03023.1 - 5.5e-27 93.9 10.9 1.7e-13 50.7 0.9 2.8 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 KFP03023.1 - 3.3e-15 55.7 2.3 9.6e-08 31.8 0.1 2.9 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 KFP03023.1 - 1.2e-05 25.5 0.1 0.0017 18.6 0.0 2.6 2 0 0 2 2 2 1 PDZ domain NRho PF16733.5 KFP03023.1 - 0.085 12.9 1.3 0.21 11.7 0.1 2.3 3 0 0 3 3 3 0 Rhomboid N-terminal domain Glyoxalase_4 PF13669.6 KFP03024.1 - 1.9e-22 79.6 0.0 2.3e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 KFP03024.1 - 9.3e-12 45.3 0.0 1.1e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KFP03024.1 - 3e-08 34.0 0.0 3.6e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KFP03024.1 - 0.00043 20.2 0.0 0.00089 19.2 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain DUF1338 PF07063.13 KFP03024.1 - 0.12 11.6 0.0 2.5 7.2 0.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1338) Myco_arth_vir_N PF09610.10 KFP03024.1 - 1.2 9.3 4.5 0.54 10.4 1.6 1.9 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Mpp10 PF04006.12 KFP03025.1 - 1.6e-202 674.3 81.1 1.9e-202 674.0 81.1 1.1 1 0 0 1 1 1 1 Mpp10 protein VRR_NUC PF08774.11 KFP03026.1 - 2.1e-24 85.7 0.0 4.5e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain zf-WRNIP1_ubi PF18279.1 KFP03026.1 - 0.002 18.6 2.1 0.0025 18.3 0.2 2.3 2 0 0 2 2 2 1 Werner helicase-interacting protein 1 ubiquitin-binding domain PRP21_like_P PF12230.8 KFP03026.1 - 0.014 15.2 1.4 0.018 14.9 0.1 1.7 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein zf-TRAF PF02176.18 KFP03026.1 - 0.048 14.4 2.5 0.081 13.6 0.1 2.6 2 0 0 2 2 2 0 TRAF-type zinc finger zf_UBZ PF18439.1 KFP03026.1 - 0.053 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Myotub-related PF06602.14 KFP03027.1 - 4.3e-69 233.1 5.4 6.6e-57 193.0 2.5 2.1 1 1 1 2 2 2 2 Myotubularin-like phosphatase domain 3-PAP PF12578.8 KFP03027.1 - 8.7e-56 187.3 0.0 1.5e-55 186.5 0.0 1.4 1 0 0 1 1 1 1 Myotubularin-associated protein RVT_1 PF00078.27 KFP03028.1 - 1.6e-31 109.6 0.0 2.3e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 KFP03028.1 - 6.6e-07 29.1 1.0 1.2e-06 28.3 1.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase thumb domain zf_C2H2_ZHX PF18387.1 KFP03029.1 - 9.2e-14 50.8 116.3 0.0013 18.3 0.6 22.2 21 2 2 23 23 23 15 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_5 PF13909.6 KFP03029.1 - 1.1e-05 25.0 0.3 6.2e-05 22.7 0.1 20.4 21 0 0 21 21 21 8 C2H2-type zinc-finger domain Peptidase_M75 PF09375.10 KFP03029.1 - 0.006 16.1 0.2 0.44 10.0 0.0 2.6 2 0 0 2 2 2 1 Imelysin DUF4817 PF16087.5 KFP03029.1 - 0.098 12.5 3.0 19 5.1 0.0 4.9 6 0 0 6 6 6 0 Helix-turn-helix domain (DUF4817) GyrB_insert PF18053.1 KFP03029.1 - 0.65 9.9 2.7 10 6.0 0.3 3.1 2 0 0 2 2 2 0 DNA gyrase B subunit insert domain IRK_C PF17655.1 KFP03031.1 - 1.3e-72 243.0 0.0 1.9e-72 242.5 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFP03031.1 - 4.4e-58 195.1 3.1 6.6e-58 194.5 3.1 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 KFP03031.1 - 0.17 11.9 10.8 0.69 9.9 10.8 2.0 1 1 0 1 1 1 0 Ion channel Pkinase PF00069.25 KFP03032.1 - 7.1e-50 169.8 0.0 1.1e-49 169.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP03032.1 - 5.2e-22 78.4 0.0 9.4e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Filament_head PF04732.14 KFP03032.1 - 0.38 11.6 26.2 0.44 11.4 8.0 2.8 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region Vps26 PF03643.15 KFP03033.1 - 5.1e-67 225.8 0.2 5.8e-67 225.6 0.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KFP03033.1 - 0.0018 18.4 0.1 0.017 15.2 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain TPR_1 PF00515.28 KFP03034.1 - 1e-15 56.8 8.2 0.00063 19.5 0.0 6.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFP03034.1 - 7.8e-12 44.4 13.8 0.058 13.5 0.0 6.8 7 0 0 7 7 6 4 Tetratricopeptide repeat zf-RING_2 PF13639.6 KFP03034.1 - 1.9e-08 34.5 13.7 1.9e-08 34.5 13.7 3.3 2 0 0 2 2 2 1 Ring finger domain TPR_11 PF13414.6 KFP03034.1 - 7.1e-08 32.0 6.8 9e-06 25.3 0.0 4.3 4 0 0 4 4 3 1 TPR repeat zf-rbx1 PF12678.7 KFP03034.1 - 5.8e-06 26.5 9.2 5.8e-06 26.5 9.2 3.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain TPR_16 PF13432.6 KFP03034.1 - 6.5e-06 26.7 0.0 0.094 13.4 0.0 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFP03034.1 - 9.3e-06 25.9 1.6 0.025 14.9 0.0 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat zf-C3HC4_2 PF13923.6 KFP03034.1 - 3.5e-05 23.5 12.8 3.5e-05 23.5 12.8 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP03034.1 - 9.1e-05 22.3 13.3 9.1e-05 22.3 13.3 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) TPR_8 PF13181.6 KFP03034.1 - 0.0007 19.6 3.9 16 6.0 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-ANAPC11 PF12861.7 KFP03034.1 - 0.0011 19.0 5.5 0.0011 19.0 5.5 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_19 PF14559.6 KFP03034.1 - 0.0046 17.4 0.1 1.5 9.4 0.0 3.8 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFP03034.1 - 0.013 15.8 3.1 0.37 11.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat BCDHK_Adom3 PF10436.9 KFP03034.1 - 0.096 12.5 8.2 0.64 9.8 5.8 2.6 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase PAM2 PF07145.15 KFP03034.1 - 0.14 11.9 0.2 0.31 10.8 0.2 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region zf-Nse PF11789.8 KFP03034.1 - 0.48 10.3 4.7 1.3 8.9 4.7 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KFP03034.1 - 2.7 8.1 15.0 2.9 8.0 11.7 2.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING-like PF08746.11 KFP03034.1 - 3.7 7.9 22.4 3.3 8.1 12.7 3.2 2 0 0 2 2 2 0 RING-like domain PIG-P PF08510.12 KFP03035.1 - 1.9e-39 134.3 1.2 2.2e-39 134.1 1.2 1.0 1 0 0 1 1 1 1 PIG-P Phage_holin_3_6 PF07332.11 KFP03035.1 - 0.11 12.5 1.1 0.15 12.1 1.1 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III AgrB PF04647.15 KFP03035.1 - 0.19 11.0 3.5 4.1 6.7 1.0 2.0 1 1 1 2 2 2 0 Accessory gene regulator B DPM2 PF07297.12 KFP03035.1 - 1.3 9.3 10.3 5.1 7.5 10.3 1.8 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Ripply PF14998.6 KFP03036.1 - 1.2e-22 80.3 0.0 1.3e-22 80.2 0.0 1.0 1 0 0 1 1 1 1 Transcription Regulator BPL_N PF09825.9 KFP03038.1 - 1.2e-17 64.0 0.0 3.7e-08 32.9 0.0 2.2 1 1 1 2 2 2 2 Biotin-protein ligase, N terminal ABC_transp_aux PF09822.9 KFP03038.1 - 9.6e-05 22.0 0.1 0.0002 20.9 0.1 1.5 1 1 0 1 1 1 1 ABC-type uncharacterized transport system CppA_C PF14507.6 KFP03038.1 - 0.036 14.8 0.1 0.11 13.2 0.1 1.9 1 1 0 1 1 1 0 CppA C-terminal BPL_LplA_LipB PF03099.19 KFP03039.1 - 2.5e-23 82.4 0.0 3.8e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 KFP03039.1 - 1e-10 41.3 0.0 2e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain SIM_C PF06621.12 KFP03040.1 - 3e-63 214.6 8.5 4e-63 214.2 8.5 1.2 1 0 0 1 1 1 1 Single-minded protein C-terminus PAS_3 PF08447.12 KFP03040.1 - 1.9e-24 85.7 0.7 1e-18 67.4 0.1 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KFP03040.1 - 2.8e-19 69.3 0.3 8.5e-14 51.6 0.1 2.6 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 KFP03040.1 - 1.2e-16 60.7 0.0 3.6e-11 43.1 0.0 2.5 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 KFP03040.1 - 0.00014 21.7 0.6 0.00027 20.8 0.6 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 KFP03040.1 - 0.00028 21.1 0.0 0.042 14.1 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 KFP03040.1 - 0.0064 16.7 0.0 0.1 12.9 0.0 2.3 2 0 0 2 2 2 1 PAS fold PMP22_Claudin PF00822.20 KFP03041.1 - 2.7e-32 112.0 7.1 3.2e-32 111.7 7.1 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP03041.1 - 8.9e-09 35.4 10.9 2.8e-07 30.5 10.9 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.11 KFP03041.1 - 0.34 10.7 7.4 0.54 10.1 6.7 1.9 1 1 0 1 1 1 0 Amastin surface glycoprotein DUF872 PF05915.12 KFP03041.1 - 1.2 9.3 3.1 2.3 8.4 1.2 2.4 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) CAF-1_p60_C PF15512.6 KFP03042.1 - 1.3e-53 182.2 22.6 1.8e-53 181.7 22.6 1.2 1 0 0 1 1 1 1 Chromatin assembly factor complex 1 subunit p60, C-terminal WD40 PF00400.32 KFP03042.1 - 4.6e-24 84.2 11.0 1.4e-06 28.9 0.5 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP03042.1 - 8.4e-14 51.6 0.3 0.001 19.3 0.4 5.4 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KFP03042.1 - 2.1e-05 23.8 0.1 0.0091 15.1 0.0 2.7 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.11 KFP03042.1 - 2.7e-05 24.2 1.0 0.0019 18.1 0.1 3.5 4 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KFP03042.1 - 0.0016 16.6 0.4 0.097 10.6 0.1 2.2 2 0 0 2 2 2 2 IKI3 family Ge1_WD40 PF16529.5 KFP03042.1 - 0.0019 17.2 0.1 0.33 9.9 0.0 3.1 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFP03042.1 - 0.041 12.5 0.4 1.3 7.6 0.0 2.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PD40 PF07676.12 KFP03042.1 - 2.1 8.4 7.1 7.7 6.6 1.2 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Dopey_N PF04118.14 KFP03043.1 - 4.9e-98 328.0 1.5 1.2e-97 326.7 1.5 1.8 1 0 0 1 1 1 1 Dopey, N-terminal adh_short PF00106.25 KFP03044.1 - 1.2e-33 116.2 0.0 8.8e-27 93.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFP03044.1 - 7.8e-25 87.8 0.0 1.5e-17 63.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP03044.1 - 9.6e-07 28.9 0.0 1.4e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KFP03044.1 - 0.0017 17.6 0.0 0.003 16.8 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein HATPase_c PF02518.26 KFP03044.1 - 0.019 15.4 0.0 0.26 11.8 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SET PF00856.28 KFP03045.1 - 6.4e-14 52.7 0.0 1.3e-13 51.7 0.0 1.5 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 KFP03045.1 - 2.4e-11 44.5 0.5 4.1e-11 43.7 0.5 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Dna2 PF08696.11 KFP03045.1 - 0.12 12.2 0.5 0.26 11.1 0.5 1.5 1 0 0 1 1 1 0 DNA replication factor Dna2 Runt PF00853.19 KFP03047.1 - 2.2e-53 179.2 0.3 3.2e-53 178.7 0.3 1.2 1 0 0 1 1 1 1 Runt domain RunxI PF08504.11 KFP03047.1 - 9.7e-43 144.9 4.7 2.1e-42 143.8 4.7 1.6 1 0 0 1 1 1 1 Runx inhibition domain DUF3037 PF11236.8 KFP03047.1 - 0.045 14.2 0.0 0.072 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) GST_C_2 PF13410.6 KFP03049.1 - 1.4e-07 31.4 0.0 2.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFP03049.1 - 2.9e-05 24.3 0.0 6.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFP03049.1 - 6.1e-05 23.4 0.0 0.00012 22.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFP03049.1 - 0.0011 19.2 0.3 0.0056 16.9 0.1 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain EST1_DNA_bind PF10373.9 KFP03049.1 - 0.025 14.1 0.1 0.034 13.6 0.1 1.2 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain GST_C_3 PF14497.6 KFP03049.1 - 0.035 14.3 0.2 0.1 12.8 0.1 1.9 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Calcipressin PF04847.12 KFP03050.1 - 6.6e-60 202.0 0.7 7.4e-60 201.9 0.7 1.0 1 0 0 1 1 1 1 Calcipressin ISK_Channel PF02060.15 KFP03051.1 - 1.1e-56 189.7 0.1 1.3e-56 189.6 0.1 1.0 1 0 0 1 1 1 1 Slow voltage-gated potassium channel TrbL PF04610.14 KFP03051.1 - 0.019 14.7 0.1 0.023 14.4 0.1 1.1 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein FAM165 PF14981.6 KFP03053.1 - 1.8e-30 104.5 4.7 1.9e-30 104.4 4.7 1.0 1 0 0 1 1 1 1 FAM165 family MadM PF03818.13 KFP03053.1 - 0.0067 16.3 0.0 0.0074 16.1 0.0 1.1 1 0 0 1 1 1 1 Malonate/sodium symporter MadM subunit ISK_Channel PF02060.15 KFP03054.1 - 2.4e-17 62.8 0.5 3e-17 62.5 0.5 1.1 1 0 0 1 1 1 1 Slow voltage-gated potassium channel Ribosomal_S6 PF01250.17 KFP03055.1 - 9.9e-15 54.6 0.0 1.2e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 OSCP PF00213.18 KFP03056.1 - 1.7e-44 152.0 0.1 1.9e-44 151.8 0.1 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF2630 PF10944.8 KFP03056.1 - 0.09 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) PH_13 PF16652.5 KFP03057.1 - 7.7e-74 246.7 0.1 7.7e-74 246.7 0.1 4.0 3 1 1 4 4 2 1 Pleckstrin homology domain SH3_9 PF14604.6 KFP03057.1 - 1.2e-68 226.7 6.7 2.7e-16 59.1 0.1 5.4 5 0 0 5 5 5 5 Variant SH3 domain SH3_1 PF00018.28 KFP03057.1 - 1e-63 210.7 14.1 1.1e-16 60.1 0.3 5.5 5 0 0 5 5 5 5 SH3 domain SH3_2 PF07653.17 KFP03057.1 - 2.8e-57 190.3 1.5 4.7e-14 51.8 0.0 5.6 5 0 0 5 5 5 5 Variant SH3 domain INTAP PF16617.5 KFP03057.1 - 1.5e-56 189.7 14.8 1.5e-56 189.7 14.8 2.0 2 0 0 2 2 2 1 Intersectin and clathrin adaptor AP2 binding region RhoGEF PF00621.20 KFP03057.1 - 5.6e-46 157.1 2.0 5.6e-46 157.1 2.0 3.2 3 1 0 3 3 1 1 RhoGEF domain EF-hand_4 PF12763.7 KFP03057.1 - 7.3e-31 106.2 0.0 1.1e-14 54.2 0.0 3.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand C2 PF00168.30 KFP03057.1 - 2.3e-21 76.0 0.0 6.3e-21 74.6 0.0 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_1 PF00036.32 KFP03057.1 - 9.9e-09 34.1 0.4 0.0029 17.1 0.0 3.5 4 0 0 4 4 3 2 EF hand EF-hand_6 PF13405.6 KFP03057.1 - 6e-07 28.9 0.2 0.39 10.8 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 KFP03057.1 - 2e-06 28.2 0.0 0.0032 17.9 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain pair PH PF00169.29 KFP03057.1 - 0.00075 20.0 0.0 0.0024 18.4 0.0 1.9 1 0 0 1 1 1 1 PH domain EF-hand_5 PF13202.6 KFP03057.1 - 0.0034 16.8 0.2 0.62 9.7 0.0 2.9 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KFP03057.1 - 0.051 13.4 0.0 0.99 9.3 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair GSH_synthase PF03199.15 KFP03057.1 - 0.1 13.1 2.7 0.35 11.3 0.6 3.2 2 1 0 2 2 2 0 Eukaryotic glutathione synthase Dockerin_1 PF00404.18 KFP03057.1 - 0.19 12.0 0.0 2.3 8.5 0.0 2.5 2 0 0 2 2 2 0 Dockerin type I domain ADH_zinc_N PF00107.26 KFP03058.1 - 6.8e-07 29.3 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFP03058.1 - 1.1e-05 25.3 0.1 2.1e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFP03058.1 - 0.061 14.4 0.0 0.16 13.0 0.0 1.8 2 1 0 2 2 2 0 Zinc-binding dehydrogenase G-patch PF01585.23 KFP03060.1 - 2.3e-17 62.6 3.0 5.2e-17 61.5 3.0 1.6 1 0 0 1 1 1 1 G-patch domain dsrm PF00035.26 KFP03060.1 - 8.4e-15 55.2 0.0 2.5e-14 53.7 0.0 1.9 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KFP03060.1 - 6.7e-12 45.5 0.0 2.4e-11 43.7 0.0 2.0 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 G-patch_2 PF12656.7 KFP03060.1 - 2.4e-07 30.8 1.0 8.4e-07 29.0 1.0 1.9 1 0 0 1 1 1 1 G-patch domain RSRP PF17069.5 KFP03060.1 - 0.00032 20.4 0.9 0.00063 19.4 0.9 1.4 1 0 0 1 1 1 1 Arginine/Serine-Rich protein 1 GARS_A PF01071.19 KFP03061.1 - 3.2e-90 301.1 0.0 6.5e-90 300.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Formyl_trans_N PF00551.19 KFP03061.1 - 9.8e-68 227.5 0.1 2e-67 226.5 0.1 1.5 1 0 0 1 1 1 1 Formyl transferase AIRS_C PF02769.22 KFP03061.1 - 3.1e-40 137.9 0.8 3.2e-39 134.5 0.0 3.0 4 0 0 4 4 4 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 KFP03061.1 - 5.1e-39 132.9 2.9 4e-36 123.7 0.2 3.8 3 1 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 KFP03061.1 - 7.3e-28 96.7 0.8 3.6e-27 94.4 0.2 2.5 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KFP03061.1 - 4.4e-17 62.5 1.6 1.8e-16 60.6 0.7 2.5 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_3 PF02655.14 KFP03061.1 - 0.0005 20.2 0.0 0.0012 18.9 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 KFP03061.1 - 0.00087 18.9 0.1 0.0024 17.5 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KFP03061.1 - 0.0093 15.5 0.3 0.029 13.8 0.1 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_2 PF08442.10 KFP03061.1 - 0.034 13.7 0.0 0.088 12.4 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.11 KFP03061.1 - 0.038 13.6 0.1 0.1 12.2 0.0 1.8 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Sacchrp_dh_NADP PF03435.18 KFP03061.1 - 0.063 13.5 0.0 0.27 11.5 0.0 2.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ATP-grasp_4 PF13535.6 KFP03061.1 - 0.066 12.8 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain DUF1992 PF09350.10 KFP03062.1 - 2.5e-23 82.0 0.1 7.2e-23 80.5 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) DnaJ PF00226.31 KFP03062.1 - 4e-11 42.9 0.2 1.6e-10 40.9 0.1 2.2 1 1 0 1 1 1 1 DnaJ domain DUF3597 PF12200.8 KFP03062.1 - 0.037 14.6 0.1 0.082 13.5 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) UPF0220 PF05255.11 KFP03063.1 - 9.3e-51 171.7 4.6 1e-50 171.5 4.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF1218 PF06749.12 KFP03063.1 - 4.2 7.9 7.3 0.95 10.0 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) Tissue_fac PF01108.17 KFP03064.1 - 2.3e-20 72.4 0.5 2.3e-20 72.4 0.5 1.8 2 0 0 2 2 2 1 Tissue factor Interfer-bind PF09294.10 KFP03064.1 - 7.3e-17 61.6 0.3 1.6e-16 60.5 0.3 1.6 1 1 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.21 KFP03064.1 - 6e-09 36.1 2.6 1.4e-07 31.8 0.1 2.7 2 1 1 3 3 3 1 Fibronectin type III domain Interfer-bind PF09294.10 KFP03065.1 - 6.4e-43 145.3 0.4 4.2e-20 72.0 0.1 3.1 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.17 KFP03065.1 - 9.4e-29 99.4 11.6 2.3e-14 53.1 1.5 3.2 3 0 0 3 3 3 2 Tissue factor fn3 PF00041.21 KFP03065.1 - 1.2e-05 25.6 11.7 0.0024 18.2 0.0 4.7 5 1 0 5 5 5 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFP03065.1 - 0.00073 20.1 2.3 0.81 10.3 0.0 3.4 3 1 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFP03066.1 - 1.8e-26 92.4 0.9 3.1e-26 91.7 0.0 1.7 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.21 KFP03066.1 - 0.0013 19.0 0.2 0.0013 19.0 0.2 2.0 3 0 0 3 3 3 1 Fibronectin type III domain Interfer-bind PF09294.10 KFP03067.1 - 4e-21 75.3 0.4 4.9e-21 75.0 0.4 1.1 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.21 KFP03067.1 - 0.042 14.2 0.4 0.072 13.4 0.4 1.3 1 0 0 1 1 1 0 Fibronectin type III domain Yae1_N PF09811.9 KFP03068.1 - 9.9e-12 44.4 34.3 4.4e+02 0.7 34.3 3.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal DUF4571 PF15137.6 KFP03069.1 - 1.1e-100 335.7 5.5 1.2e-100 335.6 5.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4571) ArlS_N PF18719.1 KFP03069.1 - 0.035 14.3 0.0 0.058 13.6 0.0 1.3 1 0 0 1 1 1 0 ArlS sensor domain GCFC PF07842.12 KFP03070.1 - 2.9e-34 119.0 0.6 8.6e-34 117.4 0.6 1.8 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein Syja_N PF02383.18 KFP03071.1 - 7.5e-70 235.8 0.2 1.1e-69 235.2 0.2 1.3 1 0 0 1 1 1 1 SacI homology domain DUF1866 PF08952.11 KFP03071.1 - 1.1e-56 190.8 0.2 6e-55 185.1 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1866) Exo_endo_phos PF03372.23 KFP03071.1 - 5.6e-16 58.8 0.1 1.1e-15 57.8 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2870 PF11069.8 KFP03072.1 - 8.9e-46 154.2 2.4 8.9e-46 154.2 2.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2870) ubiquitin PF00240.23 KFP03072.1 - 0.0042 16.8 1.1 0.051 13.3 0.0 2.8 3 0 0 3 3 3 1 Ubiquitin family NodZ PF05830.11 KFP03072.1 - 0.089 11.6 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) FAM176 PF14851.6 KFP03073.1 - 6.8e-52 175.0 0.1 1.1e-51 174.4 0.1 1.3 1 0 0 1 1 1 1 FAM176 family Gal_Lectin PF02140.18 KFP03073.1 - 6.2e-39 132.3 7.9 1.4e-19 70.3 0.8 2.4 2 0 0 2 2 2 2 Galactose binding lectin domain DUF4210 PF13915.6 KFP03073.1 - 0.11 13.1 0.6 0.41 11.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4210) VIT1 PF01988.19 KFP03073.1 - 0.47 10.3 1.5 0.58 10.0 0.2 1.7 2 0 0 2 2 2 0 VIT family Pes-10 PF07149.11 KFP03073.1 - 1.3 8.0 4.2 1.9 7.5 4.2 1.2 1 0 0 1 1 1 0 Pes-10 Npa1 PF11707.8 KFP03074.1 - 1.4e-92 310.7 2.2 7.2e-90 301.8 0.0 3.1 3 0 0 3 3 3 2 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KFP03074.1 - 7.3e-60 202.0 4.4 2.1e-59 200.5 1.5 3.3 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 Yippee-Mis18 PF03226.14 KFP03075.1 - 7.8e-18 64.6 0.4 6.2e-17 61.7 0.4 1.9 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF1289 PF06945.13 KFP03075.1 - 0.11 12.4 5.0 0.39 10.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) Pkinase PF00069.25 KFP03077.1 - 1.2e-65 221.5 0.0 1.7e-65 221.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP03077.1 - 5.1e-36 124.3 0.0 8.2e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP03077.1 - 3.8e-12 46.1 0.0 6.6e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFP03077.1 - 1.4e-06 27.8 0.2 2.8e-06 26.8 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFP03077.1 - 4.6e-05 23.1 0.6 0.00013 21.6 0.3 1.9 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KFP03077.1 - 8.3e-05 22.6 0.0 0.00019 21.4 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFP03077.1 - 0.0067 15.4 0.2 0.0067 15.4 0.2 2.1 2 0 0 2 2 2 1 Haspin like kinase domain tRNA_bind_2 PF13725.6 KFP03077.1 - 0.021 14.6 1.1 0.16 11.6 0.2 2.4 2 0 0 2 2 2 0 Possible tRNA binding domain Pkinase_fungal PF17667.1 KFP03077.1 - 0.026 13.3 0.0 0.042 12.6 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 KFP03077.1 - 0.049 13.2 0.1 0.15 11.7 0.1 1.8 1 0 0 1 1 1 0 Choline/ethanolamine kinase CTD_bind PF04818.13 KFP03078.1 - 1.8e-17 63.9 0.0 6.1e-17 62.2 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 KFP03078.1 - 5.3e-09 35.8 0.0 1.1e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP03078.1 - 0.026 14.4 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif ATP_sub_h PF10775.9 KFP03078.1 - 4.2 7.4 8.0 1.4 9.0 0.3 2.8 1 1 1 2 2 2 0 ATP synthase complex subunit h Yae1_N PF09811.9 KFP03079.1 - 3.7e-12 45.7 39.6 1.8e+04 -4.6 39.5 4.1 1 1 0 1 1 1 0 Essential protein Yae1, N terminal ANF_receptor PF01094.28 KFP03081.1 - 1.5e-75 254.6 0.0 2e-75 254.1 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 KFP03081.1 - 7.2e-54 181.7 0.1 1.1e-53 181.0 0.1 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFP03081.1 - 9.4e-47 158.0 0.1 4.6e-46 155.7 0.0 2.1 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFP03081.1 - 5.9e-19 68.4 0.0 1.2e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.6 KFP03081.1 - 8.2e-08 32.3 0.0 1.6e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein BTB PF00651.31 KFP03082.1 - 1.7e-24 86.2 0.5 4.6e-24 84.8 0.2 1.9 2 0 0 2 2 2 1 BTB/POZ domain bZIP_Maf PF03131.17 KFP03082.1 - 3.8e-16 59.4 4.9 8.9e-16 58.2 4.9 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 KFP03082.1 - 1.2e-09 38.1 7.8 2.9e-09 36.9 7.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFP03082.1 - 6.8e-07 29.3 9.1 1.6e-06 28.1 9.1 1.5 1 0 0 1 1 1 1 Basic region leucine zipper TMF_TATA_bd PF12325.8 KFP03082.1 - 0.092 13.0 3.5 0.23 11.7 3.5 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 KFP03083.1 - 0.0015 19.0 10.9 0.0023 18.5 10.9 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region Nup88 PF10168.9 KFP03083.1 - 0.031 12.1 11.0 0.037 11.8 11.0 1.0 1 0 0 1 1 1 0 Nuclear pore component FTA4 PF13093.6 KFP03083.1 - 0.046 13.6 4.3 0.053 13.4 4.3 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 GAS PF13851.6 KFP03083.1 - 0.051 12.9 14.1 0.068 12.5 14.1 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding GIT_CC PF16559.5 KFP03083.1 - 0.17 11.8 3.3 0.36 10.7 3.3 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor CENP-H PF05837.12 KFP03083.1 - 0.17 12.3 13.7 3.2 8.2 13.5 2.2 1 1 0 1 1 1 0 Centromere protein H (CENP-H) DASH_Spc19 PF08287.11 KFP03083.1 - 0.38 10.6 10.6 0.57 10.1 10.6 1.3 1 0 0 1 1 1 0 Spc19 SLATT_5 PF18160.1 KFP03083.1 - 0.63 9.3 5.2 0.9 8.8 5.2 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Spc24 PF08286.11 KFP03083.1 - 0.63 10.3 10.9 3.3 8.0 8.3 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Cdc6_C PF09079.11 KFP03083.1 - 0.79 9.7 4.6 0.98 9.4 0.6 2.2 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain Takusan PF04822.13 KFP03083.1 - 1.2 9.1 8.7 2.2 8.2 8.7 1.5 1 0 0 1 1 1 0 Takusan Seryl_tRNA_N PF02403.22 KFP03083.1 - 1.2 9.4 10.5 1.9 8.7 10.5 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain CCDC-167 PF15188.6 KFP03083.1 - 1.4 9.3 11.6 2.6 8.4 11.6 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 UPF0242 PF06785.11 KFP03083.1 - 3.6 7.7 15.6 6.9 6.7 15.5 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 KFP03083.1 - 7.7 7.0 18.0 1.6 9.2 5.2 2.3 1 1 1 2 2 2 0 Cell division protein ZapB UCH PF00443.29 KFP03084.1 - 8.1e-52 176.3 7.7 1.6e-51 175.3 7.7 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFP03084.1 - 1.9e-22 79.4 11.3 6.4e-22 77.6 11.3 2.0 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein MMR_HSR1 PF01926.23 KFP03084.1 - 0.00036 20.6 0.5 0.005 16.9 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF1115 PF06544.12 KFP03085.1 - 4.2e-18 65.8 0.3 1.8e-17 63.8 0.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) RWD PF05773.22 KFP03085.1 - 1.6e-16 60.6 0.1 3e-16 59.7 0.1 1.5 1 0 0 1 1 1 1 RWD domain MTS PF05175.14 KFP03086.1 - 1.3e-07 31.4 0.0 1.6e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 KFP03086.1 - 0.00012 21.6 0.0 0.00074 19.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KFP03086.1 - 0.0075 16.1 0.0 0.059 13.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP03086.1 - 0.011 16.4 0.0 0.02 15.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 KFP03086.1 - 0.021 14.5 0.1 0.028 14.1 0.1 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_12 PF08242.12 KFP03086.1 - 0.034 14.9 0.0 0.074 13.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_24 PF13578.6 KFP03086.1 - 0.054 14.5 0.0 0.1 13.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain NinF PF05810.12 KFP03087.1 - 0.063 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 NinF protein ADAM_spacer1 PF05986.14 KFP03088.1 - 7.8e-34 116.1 0.1 1.2e-33 115.5 0.1 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin PF01421.19 KFP03088.1 - 2.3e-22 79.9 0.1 4.9e-22 78.8 0.1 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 KFP03088.1 - 1.1e-21 77.2 15.8 1.5e-20 73.5 5.9 5.4 5 1 1 6 6 6 2 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 KFP03088.1 - 3.2e-13 50.3 1.3 7.2e-13 49.1 1.3 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFP03088.1 - 1.4e-12 48.2 1.8 3.7e-12 46.8 1.8 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like TSP_1 PF00090.19 KFP03088.1 - 1.2e-09 38.2 5.7 1.2e-09 38.2 5.7 4.3 4 0 0 4 4 3 2 Thrombospondin type 1 domain Reprolysin_4 PF13583.6 KFP03088.1 - 5e-06 26.3 0.2 8.7e-06 25.5 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFP03088.1 - 6.2e-06 26.2 0.8 1.6e-05 24.9 0.8 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFP03088.1 - 0.0011 18.8 1.0 0.0022 17.9 1.0 1.5 1 0 0 1 1 1 1 Matrixin Astacin PF01400.24 KFP03088.1 - 0.018 14.6 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) DUF3285 PF11688.8 KFP03088.1 - 0.037 14.0 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) Peptidase_M54 PF07998.11 KFP03088.1 - 0.09 12.8 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M54 DUF4953 PF16313.5 KFP03088.1 - 0.15 11.2 1.9 0.13 11.4 0.5 1.5 2 0 0 2 2 2 0 Met-zincin CxC6 PF18721.1 KFP03088.1 - 5.5 7.3 14.4 0.14 12.4 4.4 3.3 2 0 0 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases ADAM_spacer1 PF05986.14 KFP03090.1 - 3.7e-32 110.7 0.0 6.2e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 ADAM_CR_2 PF17771.1 KFP03090.1 - 9.6e-24 83.7 30.8 1.1e-22 80.3 9.7 4.3 4 1 0 4 4 4 2 ADAM cysteine-rich domain Reprolysin PF01421.19 KFP03090.1 - 8.9e-20 71.4 0.0 1.4e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease TSP_1 PF00090.19 KFP03090.1 - 4.7e-16 58.7 49.7 5.9e-09 36.0 6.6 6.1 6 0 0 6 6 6 3 Thrombospondin type 1 domain Reprolysin_5 PF13688.6 KFP03090.1 - 1.1e-12 48.5 0.2 2.1e-12 47.6 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFP03090.1 - 3.2e-11 43.8 0.0 6.2e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFP03090.1 - 0.00032 20.7 0.0 0.00065 19.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP03090.1 - 0.00033 20.4 0.0 0.00054 19.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like CxC6 PF18721.1 KFP03090.1 - 0.011 16.0 3.1 0.011 16.0 3.1 3.8 5 0 0 5 5 5 0 CxC6 like cysteine cluster associated with KDZ transposases Yae1_N PF09811.9 KFP03091.1 - 2.4e-13 49.5 43.3 1.8e+04 -8.0 43.3 4.2 1 1 0 1 1 1 0 Essential protein Yae1, N terminal CYYR1 PF10873.8 KFP03092.1 - 5.1e-75 250.9 20.4 5.5e-75 250.8 20.4 1.0 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 WBP-1 PF11669.8 KFP03092.1 - 0.00014 22.4 4.7 0.00023 21.7 4.7 1.3 1 0 0 1 1 1 1 WW domain-binding protein 1 Shisa PF13908.6 KFP03092.1 - 0.038 14.2 0.1 0.038 14.2 0.1 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Podoplanin PF05808.11 KFP03092.1 - 2.8 8.0 5.4 4.1 7.5 5.4 1.1 1 0 0 1 1 1 0 Podoplanin Ets PF00178.22 KFP03094.1 - 9.1e-34 115.8 0.3 2e-33 114.7 0.3 1.6 1 0 0 1 1 1 1 Ets-domain GABP-alpha PF11620.8 KFP03094.1 - 6.5e-32 109.6 0.8 1.3e-31 108.6 0.8 1.5 1 0 0 1 1 1 1 GA-binding protein alpha chain SAM_PNT PF02198.16 KFP03094.1 - 1.2e-28 98.9 0.1 3.7e-28 97.3 0.1 1.9 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Syntaxin-18_N PF10496.9 KFP03094.1 - 0.17 12.1 0.0 0.41 10.9 0.0 1.5 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus ATP-synt_F6 PF05511.11 KFP03095.1 - 2.3e-44 149.8 0.1 2.5e-44 149.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 DUF1707 PF08044.11 KFP03095.1 - 0.093 12.8 0.4 0.19 11.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) Ig_3 PF13927.6 KFP03096.1 - 2.2e-20 73.1 1.2 8.4e-14 51.9 0.6 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP03096.1 - 1.9e-17 63.2 1.3 9.1e-09 35.4 0.3 2.6 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFP03096.1 - 1.1e-16 60.9 1.0 7.3e-08 32.5 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin V-set domain I-set PF07679.16 KFP03096.1 - 1.4e-16 60.3 0.4 4.4e-10 39.5 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP03096.1 - 6.2e-15 55.3 1.1 2e-10 40.8 0.5 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 KFP03096.1 - 3.4e-06 26.5 0.0 0.002 17.6 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFP03096.1 - 4.9e-05 23.3 0.0 0.00083 19.4 0.0 2.6 2 1 0 2 2 2 1 C17orf99 Ig domain Izumo-Ig PF16706.5 KFP03096.1 - 0.00016 21.7 0.4 0.045 13.8 0.1 2.6 2 1 0 2 2 2 2 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 KFP03096.1 - 0.00045 20.4 1.6 6.2 7.2 0.0 3.6 3 1 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Receptor_2B4 PF11465.8 KFP03096.1 - 0.0079 16.4 0.3 2.4 8.4 0.1 2.8 1 1 1 2 2 2 1 Natural killer cell receptor 2B4 DUF4307 PF14155.6 KFP03096.1 - 0.0088 15.9 3.5 0.11 12.4 0.4 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4307) C2-set_2 PF08205.12 KFP03096.1 - 0.03 14.4 0.1 0.066 13.3 0.1 1.6 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFP03096.1 - 0.054 13.9 4.2 0.84 10.1 0.3 3.2 2 2 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain TGS PF02824.21 KFP03097.1 - 0.00024 21.1 0.0 0.00084 19.3 0.0 1.9 2 0 0 2 2 2 1 TGS domain DUF2469 PF10611.9 KFP03097.1 - 0.0031 18.0 0.0 0.01 16.4 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2469) tRNA_SAD PF07973.14 KFP03097.1 - 0.068 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Threonyl and Alanyl tRNA synthetase second additional domain RVT_1 PF00078.27 KFP03098.1 - 0.00029 20.4 0.0 0.00045 19.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Keratin PF02422.16 KFP03099.1 - 1.6e-33 114.2 19.9 1.8e-33 114.1 19.9 1.0 1 0 0 1 1 1 1 Keratin Yae1_N PF09811.9 KFP03101.1 - 2.1e-11 43.3 34.2 3.1e+02 1.2 34.2 3.6 1 1 0 1 1 1 0 Essential protein Yae1, N terminal RVT_1 PF00078.27 KFP03102.1 - 3.8e-08 33.1 0.0 6.1e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Gcn1_N PF12074.8 KFP03102.1 - 0.02 14.2 0.0 0.029 13.6 0.0 1.1 1 0 0 1 1 1 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal CENP-T_C PF15511.6 KFP03104.1 - 1.8e-08 34.5 0.1 2.2e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KFP03104.1 - 2.5e-05 24.4 0.2 3.5e-05 23.9 0.2 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KFP03104.1 - 4.6e-05 23.7 0.1 6.1e-05 23.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 KFP03104.1 - 0.00017 21.9 0.3 0.00019 21.8 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFP03104.1 - 0.00028 21.1 0.1 0.00046 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFP03104.1 - 0.0059 16.7 0.0 0.0067 16.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KFP03104.1 - 0.024 14.6 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KFP03104.1 - 0.21 11.4 0.1 0.25 11.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Guanylate_cyc PF00211.20 KFP03106.1 - 2.7e-53 180.3 0.0 3.8e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 KFP03108.1 - 1.9e-61 206.9 0.1 2.7e-61 206.4 0.1 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF512 PF04459.12 KFP03108.1 - 0.027 13.8 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF512) LAP1C PF05609.12 KFP03108.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF2207 PF09972.9 KFP03108.1 - 0.24 10.1 2.9 0.99 8.1 0.9 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) AC_N PF16214.5 KFP03108.1 - 0.46 9.6 0.0 0.46 9.6 0.0 2.5 3 0 0 3 3 3 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Dynamin_N PF00350.23 KFP03109.1 - 7.6e-15 55.4 0.0 3.5e-13 50.0 0.0 2.6 2 1 0 2 2 2 1 Dynamin family EHD_N PF16880.5 KFP03109.1 - 7.4e-11 41.7 0.0 2.2e-10 40.3 0.0 1.9 1 0 0 1 1 1 1 N-terminal EH-domain containing protein MMR_HSR1 PF01926.23 KFP03109.1 - 1.3e-08 34.9 0.0 3.2e-08 33.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP03109.1 - 0.0008 19.4 0.0 0.2 11.5 0.0 3.5 4 0 0 4 4 4 1 RsgA GTPase Roc PF08477.13 KFP03109.1 - 0.067 13.4 0.0 7.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KFP03109.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain HLH PF00010.26 KFP03110.1 - 1.5e-07 31.2 0.9 4e-07 29.9 0.1 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4940 PF16298.5 KFP03110.1 - 0.079 12.6 3.6 0.18 11.5 2.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4940) Lzipper-MIP1 PF14389.6 KFP03110.1 - 0.45 10.8 20.6 3.5 8.0 16.6 3.1 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 zf-H2C2_2 PF13465.6 KFP03111.1 - 1.3e-11 44.3 10.6 1.4e-07 31.6 3.3 4.3 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFP03111.1 - 3.5e-10 39.8 28.3 2.2e-05 24.7 3.3 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFP03111.1 - 1.1e-05 25.3 1.0 1.1e-05 25.3 1.0 3.2 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KFP03111.1 - 0.0006 20.4 24.9 0.16 12.9 1.9 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 KFP03111.1 - 0.0053 17.1 6.1 0.012 16.0 1.1 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP03111.1 - 0.016 15.5 0.6 0.016 15.5 0.6 3.4 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KFP03111.1 - 0.026 15.1 0.6 0.026 15.1 0.6 3.5 1 1 3 4 4 4 0 FOXP coiled-coil domain zf_C2H2_ZHX PF18387.1 KFP03111.1 - 0.049 13.3 0.6 0.13 11.9 0.6 1.7 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf_ZIC PF18366.1 KFP03111.1 - 7.2 6.8 13.8 2.6 8.2 0.8 3.7 3 2 1 4 4 4 0 Zic proteins zinc finger domain Pam16 PF03656.13 KFP03112.1 - 2.7e-53 179.3 5.2 2.9e-53 179.2 5.2 1.0 1 0 0 1 1 1 1 Pam16 Integrase_Zn PF02022.19 KFP03112.1 - 0.82 9.7 3.0 22 5.1 0.2 2.3 2 0 0 2 2 2 0 Integrase Zinc binding domain WD40_4 PF16300.5 KFP03113.1 - 1.8e-19 69.3 0.1 3.5e-19 68.4 0.1 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KFP03113.1 - 1.6e-13 50.9 1.1 0.0011 19.7 0.0 4.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP03113.1 - 1.8e-06 28.2 0.0 0.025 14.9 0.0 2.8 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain VP40 PF07447.12 KFP03113.1 - 0.063 12.4 0.2 4.2 6.4 0.1 2.2 1 1 0 2 2 2 0 Matrix protein VP40 PD40 PF07676.12 KFP03113.1 - 0.16 11.9 0.8 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 KFP03114.1 - 6.7e-13 48.9 2.4 0.0002 22.1 0.1 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP03114.1 - 3.5e-06 27.2 0.0 0.0011 19.2 0.0 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1899 PF08953.11 KFP03114.1 - 0.017 15.0 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1899) Ank_2 PF12796.7 KFP03115.1 - 5e-36 123.2 0.5 1.6e-14 54.3 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFP03115.1 - 3.4e-28 96.8 2.0 3e-05 24.2 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 KFP03115.1 - 8.5e-28 93.3 0.3 3.1e-05 24.0 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KFP03115.1 - 1.2e-24 86.0 0.2 7.3e-08 32.5 0.0 4.8 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP03115.1 - 5.1e-24 84.3 0.6 1.6e-08 34.9 0.0 4.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) SAM_1 PF00536.30 KFP03115.1 - 9.7e-13 48.4 0.0 2.1e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP03115.1 - 4.5e-12 45.9 0.0 9.1e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 KFP03115.1 - 0.061 13.4 0.1 0.27 11.4 0.0 2.0 2 0 0 2 2 2 0 IGR protein motif YlqD PF11068.8 KFP03115.1 - 0.1 13.0 2.3 0.19 12.1 2.3 1.3 1 0 0 1 1 1 0 YlqD protein FH2 PF02181.23 KFP03115.1 - 0.25 10.4 1.8 0.4 9.8 1.8 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain 7tm_2 PF00002.24 KFP03116.1 - 2e-75 253.3 16.5 2.5e-75 252.9 16.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFP03116.1 - 1.9e-18 66.5 3.9 3.4e-18 65.7 3.9 1.4 1 0 0 1 1 1 1 Hormone receptor domain Dicty_CAR PF05462.11 KFP03116.1 - 0.037 13.1 16.6 0.072 12.2 16.6 1.5 1 1 0 1 1 1 0 Slime mold cyclic AMP receptor PulG PF11773.8 KFP03116.1 - 0.12 12.2 0.5 0.27 11.1 0.5 1.6 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin Cluap1 PF10234.9 KFP03117.1 - 3.5e-112 374.2 11.2 5e-112 373.7 11.2 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 SseC PF04888.12 KFP03117.1 - 2e-05 24.4 2.0 2.4e-05 24.1 1.2 1.6 1 1 0 1 1 1 1 Secretion system effector C (SseC) like family DUF3445 PF11927.8 KFP03117.1 - 0.13 11.9 3.1 0.21 11.2 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) A_deaminase_N PF08451.11 KFP03117.1 - 0.33 11.3 6.5 1.1 9.6 6.5 1.9 1 0 0 1 1 1 0 Adenosine/AMP deaminase N-terminal DUF3332 PF11810.8 KFP03117.1 - 1.3 8.6 5.5 2.3 7.8 5.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) BUD22 PF09073.10 KFP03117.1 - 1.6 8.0 21.0 2.2 7.5 21.0 1.3 1 0 0 1 1 1 0 BUD22 Spore_III_AB PF09548.10 KFP03117.1 - 6.7 6.8 15.1 0.47 10.5 3.2 2.3 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Pkinase PF00069.25 KFP03118.1 - 3.5e-53 180.7 0.0 4.3e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP03118.1 - 4.2e-30 104.9 0.0 4.7e-30 104.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP03118.1 - 3.7e-07 29.7 0.0 5e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFP03118.1 - 0.00092 19.2 0.0 0.26 11.2 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KFP03118.1 - 0.001 18.4 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KFP03118.1 - 0.016 14.2 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Xpo1 PF08389.12 KFP03119.1 - 9.7e-25 87.4 18.1 1e-22 80.8 0.1 6.6 6 1 0 6 6 6 4 Exportin 1-like protein IBN_N PF03810.19 KFP03119.1 - 6.8e-10 38.7 1.3 6.1e-09 35.7 0.0 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain NDK PF00334.19 KFP03120.1 - 5e-55 185.2 0.0 5.7e-55 185.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.18 KFP03120.1 - 0.039 14.5 0.0 0.067 13.7 0.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ adh_short_C2 PF13561.6 KFP03121.1 - 6.4e-54 183.0 0.1 8.7e-54 182.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFP03121.1 - 3.7e-44 150.5 0.1 4.8e-44 150.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFP03121.1 - 1.2e-08 35.1 0.2 1.8e-08 34.5 0.2 1.1 1 0 0 1 1 1 1 KR domain His_biosynth PF00977.21 KFP03121.1 - 0.048 13.1 0.1 0.088 12.2 0.1 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein 3HCDH_N PF02737.18 KFP03121.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KFP03121.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Septin PF00735.18 KFP03122.1 - 2.9e-90 302.4 0.1 3.4e-90 302.1 0.1 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFP03122.1 - 1.1e-07 32.0 0.2 2.3e-07 30.9 0.2 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP03122.1 - 2.3e-06 27.6 0.9 4.2e-05 23.5 0.3 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KFP03122.1 - 3.7e-05 23.9 2.0 0.0017 18.4 1.0 2.3 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.16 KFP03122.1 - 5.5e-05 22.6 0.1 8.6e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 KFP03122.1 - 0.00037 20.7 0.1 0.00071 19.8 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KFP03122.1 - 0.00066 20.1 0.2 0.008 16.6 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 KFP03122.1 - 0.0017 18.9 0.8 0.0053 17.3 0.3 1.8 1 1 0 2 2 2 1 ABC transporter GTP_EFTU PF00009.27 KFP03122.1 - 0.0017 17.9 0.9 1.1 8.7 0.1 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain IIGP PF05049.13 KFP03122.1 - 0.002 17.3 0.1 0.05 12.6 0.0 2.2 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.18 KFP03122.1 - 0.0024 17.3 0.1 0.0039 16.6 0.1 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Gtr1_RagA PF04670.12 KFP03122.1 - 0.0032 16.8 0.7 0.28 10.5 0.0 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Ras PF00071.22 KFP03122.1 - 0.008 15.8 0.1 0.019 14.5 0.1 1.7 1 1 0 1 1 1 1 Ras family AAA_22 PF13401.6 KFP03122.1 - 0.015 15.6 0.2 0.036 14.3 0.1 1.8 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFP03122.1 - 0.022 14.3 0.2 0.035 13.6 0.2 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KFP03122.1 - 0.025 14.3 0.2 0.2 11.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KFP03122.1 - 0.025 14.3 0.1 0.047 13.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 KFP03122.1 - 0.036 13.2 1.5 0.36 10.0 0.1 2.2 2 1 1 3 3 3 0 G-protein alpha subunit AAA_32 PF13654.6 KFP03122.1 - 0.036 12.9 0.0 0.059 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KFP03122.1 - 0.067 12.9 0.3 0.15 11.8 0.1 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.22 KFP03122.1 - 0.079 12.1 0.3 0.13 11.5 0.3 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KFP03122.1 - 0.13 12.7 0.3 0.33 11.3 0.0 1.9 2 0 0 2 2 2 0 RNA helicase DUF1542 PF07564.11 KFP03122.1 - 0.13 12.4 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) IP_trans PF02121.18 KFP03123.1 - 3.8e-101 337.8 0.1 4.3e-101 337.6 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein TPR_8 PF13181.6 KFP03124.1 - 9.7e-17 59.7 4.9 0.0021 18.1 0.0 7.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFP03124.1 - 8.4e-16 56.7 11.6 0.0034 17.4 0.0 8.0 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFP03124.1 - 2.1e-13 49.4 12.5 0.0085 15.9 0.0 8.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFP03124.1 - 4.1e-12 45.8 0.2 0.025 15.4 0.0 6.7 2 2 5 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFP03124.1 - 2.7e-10 40.4 7.3 0.00012 22.3 0.0 5.6 5 2 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP03124.1 - 6.7e-07 29.4 12.9 0.00049 20.3 0.3 3.7 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KFP03124.1 - 2.1e-05 25.0 0.0 0.2 12.3 0.0 3.9 3 2 1 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFP03124.1 - 2.5e-05 24.7 9.6 0.02 15.4 0.1 4.8 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFP03124.1 - 0.00059 20.0 1.8 30 5.3 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFP03124.1 - 0.00069 19.2 0.1 0.88 9.3 0.0 4.5 5 0 0 5 5 5 1 TPR repeat TPR_15 PF13429.6 KFP03124.1 - 0.0042 16.3 0.0 2.1 7.5 0.0 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFP03124.1 - 0.012 15.7 2.1 0.77 9.9 0.1 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP03124.1 - 0.029 14.4 5.9 9.4 6.5 0.0 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFP03124.1 - 0.051 14.2 2.3 64 4.5 0.0 4.8 5 0 0 5 5 3 0 Tetratricopeptide repeat FolB PF02152.18 KFP03124.1 - 0.11 13.1 0.4 0.82 10.2 0.2 2.2 2 0 0 2 2 2 0 Dihydroneopterin aldolase WD40 PF00400.32 KFP03125.1 - 6.2e-48 159.8 46.3 1.1e-06 29.3 0.1 20.5 21 0 0 21 21 21 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP03125.1 - 2e-22 79.3 0.0 0.0019 18.5 0.2 10.8 9 2 4 13 13 13 5 Anaphase-promoting complex subunit 4 WD40 domain DUF667 PF05018.13 KFP03125.1 - 1.1e-12 48.0 0.0 1.9e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Ge1_WD40 PF16529.5 KFP03125.1 - 2.1e-06 27.0 3.0 0.019 13.9 0.0 5.1 4 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein HELP PF03451.14 KFP03125.1 - 0.0015 18.4 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 2 HELP motif RAB3GAP2_N PF14655.6 KFP03125.1 - 0.0043 16.4 0.4 0.65 9.2 0.0 3.6 3 1 1 4 4 4 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Nup160 PF11715.8 KFP03125.1 - 0.023 13.4 3.3 0.31 9.6 0.0 4.1 5 1 1 6 6 6 0 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KFP03125.1 - 0.052 13.6 0.0 9.4 6.3 0.0 3.7 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.11 KFP03125.1 - 0.068 11.9 0.2 4.9 5.8 0.1 3.7 5 1 0 5 5 5 0 Nup133 N terminal like Nbas_N PF15492.6 KFP03125.1 - 0.18 11.1 1.5 12 5.2 0.0 3.9 3 2 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal EF_assoc_2 PF08356.12 KFP03126.1 - 3.6e-36 123.0 0.0 7.9e-36 121.9 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 KFP03126.1 - 2.8e-23 81.3 0.6 1.9e-22 78.6 0.0 2.3 2 1 0 2 2 2 1 EF hand associated Ras PF00071.22 KFP03126.1 - 5.6e-21 74.8 0.0 7.1e-16 58.2 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KFP03126.1 - 1.2e-08 35.2 0.0 2.2e-05 24.6 0.0 2.8 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_7 PF13499.6 KFP03126.1 - 1.1e-06 29.0 0.1 0.0034 17.8 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP03126.1 - 1.9e-06 27.4 0.9 0.00022 20.9 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KFP03126.1 - 2.1e-06 26.9 0.7 0.0014 18.0 0.1 2.5 2 0 0 2 2 2 2 EF hand MMR_HSR1 PF01926.23 KFP03126.1 - 0.00025 21.1 0.0 0.5 10.5 0.0 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 KFP03126.1 - 0.00029 21.0 0.1 0.14 12.2 0.0 2.3 2 0 0 2 2 2 2 Dynamin family EF-hand_5 PF13202.6 KFP03126.1 - 0.00097 18.5 0.1 0.0022 17.4 0.1 1.6 1 0 0 1 1 1 1 EF hand RsgA_GTPase PF03193.16 KFP03126.1 - 0.028 14.3 0.1 42 4.0 0.0 4.3 5 0 0 5 5 5 0 RsgA GTPase Arf PF00025.21 KFP03126.1 - 0.035 13.5 0.0 0.36 10.2 0.0 2.5 3 1 0 3 3 3 0 ADP-ribosylation factor family AAA_14 PF13173.6 KFP03126.1 - 0.046 13.8 0.0 4.2 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain EF-hand_10 PF14788.6 KFP03126.1 - 0.047 13.6 1.1 1.5 8.7 0.1 2.5 2 0 0 2 2 2 0 EF hand SPARC_Ca_bdg PF10591.9 KFP03126.1 - 0.057 13.7 0.1 4.5 7.6 0.0 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region ABC_tran PF00005.27 KFP03126.1 - 0.075 13.5 0.0 7.3 7.1 0.0 2.4 2 0 0 2 2 2 0 ABC transporter EF-hand_8 PF13833.6 KFP03126.1 - 0.19 11.6 0.1 33 4.4 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain pair U-box PF04564.15 KFP03127.1 - 3.5e-31 107.2 0.0 5.7e-31 106.5 0.0 1.3 1 0 0 1 1 1 1 U-box domain CHIP_TPR_N PF18391.1 KFP03127.1 - 1.5e-25 89.7 14.5 1.5e-25 89.7 14.5 1.7 2 0 0 2 2 2 1 CHIP N-terminal tetratricopeptide repeat domain TPR_1 PF00515.28 KFP03127.1 - 8.4e-16 57.0 6.9 8.5e-10 38.0 0.8 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFP03127.1 - 1.5e-12 46.6 5.9 1e-05 25.2 0.6 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP03127.1 - 4e-11 43.0 1.6 8.8e-11 41.9 1.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KFP03127.1 - 7.6e-11 42.2 10.9 1.5e-08 34.8 4.6 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP03127.1 - 4.5e-10 38.9 4.1 0.00024 21.1 0.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFP03127.1 - 1.7e-07 31.6 2.9 4.4e-07 30.3 2.9 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFP03127.1 - 1.9e-06 27.4 0.6 0.0067 16.1 0.0 2.4 1 1 1 2 2 2 2 TPR repeat TPR_17 PF13431.6 KFP03127.1 - 1.5e-05 25.0 1.2 0.37 11.3 0.3 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFP03127.1 - 1.7e-05 24.8 0.5 4e-05 23.7 0.5 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFP03127.1 - 2.1e-05 25.1 0.2 3.9e-05 24.2 0.2 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFP03127.1 - 5.2e-05 23.0 3.4 0.14 12.3 0.3 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP03127.1 - 0.0002 21.9 0.3 0.016 16.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFP03127.1 - 0.00075 20.0 7.1 0.62 10.8 0.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 KFP03127.1 - 0.0055 16.1 1.2 0.044 13.3 0.1 2.3 2 0 0 2 2 2 1 SHNi-TPR TPR_10 PF13374.6 KFP03127.1 - 0.0091 15.8 3.2 0.45 10.5 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-NOSIP PF15906.5 KFP03127.1 - 0.06 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein TPR_20 PF14561.6 KFP03127.1 - 1 9.7 9.4 4.3 7.7 2.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Cupin_8 PF13621.6 KFP03128.1 - 4e-09 36.5 0.4 4e-09 36.5 0.4 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KFP03128.1 - 0.0002 20.9 0.3 0.0003 20.4 0.3 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 KFP03128.1 - 0.00087 19.7 0.0 0.0019 18.6 0.0 1.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KFP03128.1 - 0.0023 17.6 0.7 0.016 14.9 0.7 2.0 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KFP03128.1 - 0.019 14.5 0.1 0.18 11.4 0.1 2.0 1 1 0 1 1 1 0 Cupin WD40 PF00400.32 KFP03129.1 - 7.5e-17 61.4 6.6 1.4e-05 25.8 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP03129.1 - 0.00029 21.1 0.4 1.3 9.4 0.0 3.9 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain LRR_6 PF13516.6 KFP03130.1 - 8.9e-12 44.1 11.0 0.067 13.3 0.0 8.6 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.7 KFP03130.1 - 1e-08 35.3 2.4 0.059 13.8 0.1 4.9 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP03130.1 - 0.00015 21.4 3.9 1.3 8.8 0.5 4.6 4 1 0 4 4 4 2 Leucine rich repeat F-box-like PF12937.7 KFP03130.1 - 0.0038 17.1 1.0 0.014 15.2 1.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 KFP03130.1 - 0.0083 16.5 14.4 0.46 11.2 0.0 6.5 7 1 0 7 7 7 2 Leucine Rich Repeat F-box PF00646.33 KFP03130.1 - 0.034 14.0 0.1 0.034 14.0 0.1 3.0 3 0 0 3 3 3 0 F-box domain Methyltransf_31 PF13847.6 KFP03132.1 - 0.004 17.0 0.0 0.0048 16.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP03132.1 - 0.0062 16.4 0.0 0.0067 16.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP03132.1 - 0.03 15.0 0.0 0.045 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KFP03132.1 - 0.058 14.1 0.0 0.083 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF4219 PF13961.6 KFP03132.1 - 8.2 6.2 6.4 18 5.1 2.9 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4219) RBD-FIP PF09457.10 KFP03133.1 - 0.0089 15.9 3.1 1.6 8.7 0.5 3.9 2 1 0 2 2 2 1 FIP domain DUF3600 PF12207.8 KFP03133.1 - 0.015 15.3 1.5 0.068 13.1 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3600) DIRP PF06584.13 KFP03133.1 - 0.03 14.5 0.4 0.12 12.5 0.1 2.2 2 0 0 2 2 2 0 DIRP Ribosomal_S20p PF01649.18 KFP03133.1 - 0.42 11.3 8.1 4.7 7.9 0.2 3.6 3 1 1 4 4 4 0 Ribosomal protein S20 EzrA PF06160.12 KFP03133.1 - 2 6.5 19.8 0.0081 14.4 7.1 2.7 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA BLOC1S3 PF15753.5 KFP03133.1 - 2.1 8.5 9.9 0.32 11.1 5.7 1.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF1664 PF07889.12 KFP03133.1 - 9.3 6.3 11.8 5.6 7.0 5.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) ParA PF10609.9 KFP03134.1 - 5.9e-100 333.8 0.0 6.6e-100 333.6 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KFP03134.1 - 1.2e-12 48.0 0.0 6.2e-12 45.7 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 KFP03134.1 - 1.4e-08 34.4 0.0 5.7e-08 32.4 0.0 1.8 1 1 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.6 KFP03134.1 - 2.5e-08 34.1 0.3 1.7e-07 31.3 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_26 PF13500.6 KFP03134.1 - 6.6e-07 29.3 0.0 4.1e-06 26.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KFP03134.1 - 8.2e-07 28.5 0.9 5.2e-06 25.9 0.1 2.4 2 1 1 3 3 3 1 Anion-transporting ATPase Fer4_NifH PF00142.18 KFP03134.1 - 3.1e-05 23.6 0.0 0.0016 17.9 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MeaB PF03308.16 KFP03134.1 - 3.9e-05 22.8 0.1 5.4e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CBP_BcsQ PF06564.12 KFP03134.1 - 0.0011 18.5 0.0 0.0038 16.7 0.0 1.7 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 KFP03134.1 - 0.0045 16.6 0.0 0.0099 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KFP03134.1 - 0.009 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase KTI12 PF08433.10 KFP03134.1 - 0.013 15.0 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SRP54 PF00448.22 KFP03134.1 - 0.016 14.9 0.1 0.062 12.9 0.1 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 KFP03134.1 - 0.018 14.2 0.1 0.028 13.6 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 KFP03134.1 - 0.031 13.5 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin CLP1_P PF16575.5 KFP03134.1 - 0.048 13.5 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NTPase_1 PF03266.15 KFP03134.1 - 0.12 12.3 0.2 0.24 11.3 0.2 1.5 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.6 KFP03134.1 - 0.16 11.7 0.1 0.3 10.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFP03134.1 - 0.29 11.0 1.4 0.53 10.2 0.8 1.7 2 0 0 2 2 2 0 RsgA GTPase SPRY PF00622.28 KFP03135.1 - 2.6e-19 69.5 0.1 6.3e-19 68.3 0.1 1.6 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.16 KFP03135.1 - 0.00017 21.9 1.6 0.00035 20.9 1.6 1.5 1 0 0 1 1 1 1 SOCS box PDZ PF00595.24 KFP03136.1 - 2.4e-32 111.1 2.7 4e-20 72.0 0.1 2.1 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFP03136.1 - 3.9e-13 49.0 0.7 1.9e-07 30.8 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFP03136.1 - 7.3e-08 32.6 0.6 0.00093 19.5 0.1 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_assoc PF10600.9 KFP03136.1 - 0.0016 19.2 1.4 0.0028 18.5 1.4 1.4 1 0 0 1 1 1 1 PDZ-associated domain of NMDA receptors ThiS-like PF14453.6 KFP03136.1 - 0.17 11.9 0.1 1.1e+02 3.0 0.1 3.1 2 1 1 3 3 3 0 ThiS-like ubiquitin Fur_reg_FbpA PF13076.6 KFP03136.1 - 0.95 9.2 2.5 32 4.3 0.0 2.6 3 0 0 3 3 3 0 Fur-regulated basic protein A efb-c PF12199.8 KFP03137.1 - 0.019 15.0 0.3 0.022 14.8 0.3 1.1 1 0 0 1 1 1 0 Extracellular fibrinogen binding protein C terminal L27_1 PF09058.10 KFP03137.1 - 0.029 14.4 3.1 0.064 13.3 0.3 2.1 2 0 0 2 2 2 0 L27_1 Phage_ABA_S PF18066.1 KFP03137.1 - 0.044 14.5 0.5 0.045 14.4 0.5 1.1 1 0 0 1 1 1 0 Phage ABA sandwich domain TMEM126 PF07114.11 KFP03138.1 - 1.8e-73 245.8 0.8 2.2e-73 245.5 0.8 1.0 1 0 0 1 1 1 1 Transmembrane protein 126 DUF4618 PF15397.6 KFP03139.1 - 0.15 11.5 12.9 0.16 11.3 12.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF1664 PF07889.12 KFP03139.1 - 0.47 10.5 4.7 0.3 11.1 1.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Cortex-I_coil PF09304.10 KFP03139.1 - 0.99 9.6 9.7 0.21 11.8 2.4 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil ANTH PF07651.16 KFP03140.1 - 9.8e-83 277.3 0.8 1.4e-82 276.9 0.8 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KFP03140.1 - 9.7e-14 51.5 0.1 2e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 ENTH domain Ribosomal_60s PF00428.19 KFP03140.1 - 2.9 8.6 5.6 33 5.2 1.0 2.6 1 1 1 2 2 2 0 60s Acidic ribosomal protein WD40 PF00400.32 KFP03141.1 - 4.4e-11 43.1 9.7 1e-05 26.1 0.0 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP03141.1 - 0.0019 18.5 0.3 8.1 6.8 0.0 4.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP03141.1 - 0.0021 16.8 0.0 0.0081 14.8 0.0 1.9 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Lipoprotein_3 PF00938.17 KFP03141.1 - 0.16 12.2 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 Lipoprotein DUF775 PF05603.12 KFP03142.1 - 5.3e-49 166.5 0.3 7.8e-49 165.9 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF775) RVT_1 PF00078.27 KFP03144.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Yae1_N PF09811.9 KFP03145.1 - 9.1e-11 41.3 63.7 0.65 9.7 2.4 11.2 10 1 1 11 11 11 11 Essential protein Yae1, N terminal RRM_1 PF00076.22 KFP03147.1 - 0.00022 21.0 0.0 0.00045 20.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.8 KFP03147.1 - 0.27 11.6 2.1 0.5 10.7 2.1 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP03147.1 - 2.2 8.8 5.0 4.3 7.9 5.0 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type PAM2 PF07145.15 KFP03148.1 - 6.6e-07 28.6 0.2 6.6e-07 28.6 0.2 1.8 2 0 0 2 2 2 1 Ataxin-2 C-terminal region DUF3886 PF13025.6 KFP03148.1 - 4.5 7.5 10.2 1.2 9.3 5.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3886) ATP-synt_ab PF00006.25 KFP03149.1 - 1.3e-49 168.7 0.0 1.8e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Homeodomain PF00046.29 KFP03150.1 - 1.2e-12 47.5 1.8 1.4e-12 47.3 1.8 1.1 1 0 0 1 1 1 1 Homeodomain Ig_2 PF13895.6 KFP03151.1 - 6.4e-52 173.8 8.9 1.3e-12 47.9 0.4 6.2 5 1 1 6 6 6 5 Immunoglobulin domain Ig_3 PF13927.6 KFP03151.1 - 7.2e-49 164.3 10.7 2.2e-13 50.6 0.3 6.3 6 0 0 6 6 6 5 Immunoglobulin domain I-set PF07679.16 KFP03151.1 - 2.6e-40 136.4 0.5 4.2e-08 33.2 0.1 7.7 6 3 0 6 6 6 5 Immunoglobulin I-set domain ig PF00047.25 KFP03151.1 - 6.1e-24 84.0 18.7 5.8e-05 23.2 0.3 8.4 6 4 0 6 6 6 5 Immunoglobulin domain V-set PF07686.17 KFP03151.1 - 2.8e-23 82.2 12.6 0.0026 17.9 0.0 9.2 6 4 3 9 9 9 5 Immunoglobulin V-set domain Ig_4 PF16680.5 KFP03151.1 - 4.3e-15 55.7 0.0 0.0069 16.6 0.0 4.8 4 0 0 4 4 4 4 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFP03151.1 - 9.4e-12 45.2 0.1 0.066 13.6 0.0 5.5 6 0 0 6 6 6 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFP03151.1 - 1.4e-11 44.3 0.0 0.22 11.6 0.0 5.6 5 0 0 5 5 5 3 Izumo-like Immunoglobulin domain C1-set PF07654.15 KFP03151.1 - 3.6e-09 36.9 3.1 0.0068 16.8 0.0 5.4 5 1 1 6 6 6 2 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFP03151.1 - 3e-08 33.1 0.0 0.26 10.9 0.0 5.1 5 0 0 5 5 5 2 Immunoglobulin domain C2-set_2 PF08205.12 KFP03151.1 - 7.1e-07 29.2 13.3 8.8e-05 22.5 0.5 5.6 5 2 1 6 6 6 2 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 KFP03151.1 - 0.024 14.7 3.5 26 4.9 0.1 5.1 5 2 0 5 5 5 0 C17orf99 Ig domain ASH PF15780.5 KFP03151.1 - 0.039 14.2 0.8 8.3 6.7 0.0 3.7 3 1 0 3 3 3 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin AP-5_subunit_s1 PF15001.6 KFP03152.1 - 5.7e-33 114.6 0.0 6.1e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 AP-5 complex subunit sigma-1 TRC8_N PF13705.6 KFP03153.1 - 3.5e-76 257.1 16.3 3.9e-76 257.0 16.3 1.0 1 0 0 1 1 1 1 TRC8 N-terminal domain IQ PF00612.27 KFP03153.1 - 0.15 12.0 1.0 0.77 9.7 1.0 2.3 1 0 0 1 1 1 0 IQ calmodulin-binding motif CbiQ PF02361.16 KFP03153.1 - 3.3 7.3 14.2 1.2 8.7 2.0 2.2 1 1 1 2 2 2 0 Cobalt transport protein Peptidase_M14 PF00246.24 KFP03154.1 - 8.8e-77 258.7 0.1 1.2e-76 258.3 0.1 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase F5_F8_type_C PF00754.25 KFP03154.1 - 4.4e-29 101.2 0.3 9.9e-29 100.0 0.1 1.8 2 0 0 2 2 2 1 F5/8 type C domain AstE_AspA PF04952.14 KFP03154.1 - 0.16 11.0 0.1 0.36 9.9 0.0 1.6 2 0 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family Vps16_N PF04841.13 KFP03155.1 - 2.8e-121 405.1 0.0 3.5e-121 404.8 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 KFP03155.1 - 7.1e-114 380.2 0.6 1.1e-113 379.5 0.6 1.3 1 0 0 1 1 1 1 Vps16, C-terminal region Iso_dh PF00180.20 KFP03156.1 - 1.3e-73 248.2 0.1 1.6e-73 247.9 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase AAA_3 PF07726.11 KFP03156.1 - 0.022 14.6 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Dynactin PF12455.8 KFP03157.1 - 5.2e-47 160.5 1.9 5.2e-47 160.5 1.9 4.6 2 1 1 5 5 5 1 Dynein associated protein Filament PF00038.21 KFP03157.1 - 0.0035 17.0 78.8 0.18 11.4 24.7 3.9 2 1 0 2 2 2 2 Intermediate filament protein TolA_bind_tri PF16331.5 KFP03157.1 - 0.0043 17.1 11.7 0.0043 17.1 11.7 6.8 4 2 3 7 7 7 2 TolA binding protein trimerisation Spc7 PF08317.11 KFP03157.1 - 0.14 11.0 86.3 0.5 9.2 27.2 4.7 1 1 3 4 4 4 0 Spc7 kinetochore protein Phage_GP20 PF06810.11 KFP03157.1 - 0.21 11.4 72.2 0.2 11.4 18.0 4.9 1 1 2 4 4 4 0 Phage minor structural protein GP20 BRI3BP PF14965.6 KFP03157.1 - 1.8 8.0 5.9 3 7.3 0.0 3.6 3 1 1 4 4 4 0 Negative regulator of p53/TP53 GAS PF13851.6 KFP03157.1 - 2.2 7.6 92.7 0.26 10.6 26.0 5.5 2 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding CAP_GLY PF01302.25 KFP03158.1 - 5.5e-25 87.2 2.0 7e-25 86.8 2.0 1.1 1 0 0 1 1 1 1 CAP-Gly domain adh_short PF00106.25 KFP03159.1 - 6.3e-07 29.1 0.0 6.6e-07 29.0 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP03159.1 - 3.2e-05 23.6 0.0 3.6e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Neurexophilin PF06312.12 KFP03161.1 - 1.8e-47 161.5 0.0 2.8e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Neurexophilin Filamin PF00630.19 KFP03161.1 - 4.4e-05 24.2 0.0 9.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Filamin/ABP280 repeat CD20 PF04103.15 KFP03161.1 - 0.059 13.5 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 CD20-like family Invasin_D3 PF09134.10 KFP03161.1 - 0.2 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Invasin, domain 3 Ank_2 PF12796.7 KFP03162.1 - 8.6e-25 87.2 8.7 2.6e-12 47.1 0.2 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP03162.1 - 9.1e-23 80.3 3.3 0.00014 22.3 0.0 5.8 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KFP03162.1 - 2.1e-21 75.3 9.2 0.0003 21.1 0.1 6.9 6 2 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 KFP03162.1 - 3.5e-18 63.8 3.7 0.067 13.8 0.1 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KFP03162.1 - 1.4e-11 44.4 8.1 0.0067 16.7 0.2 5.8 3 2 2 5 5 5 4 Ankyrin repeats (many copies) PD-C2-AF1 PF09310.10 KFP03162.1 - 0.0035 16.8 0.0 0.015 14.7 0.0 2.0 2 0 0 2 2 2 1 POU domain, class 2, associating factor 1 Zona_pellucida PF00100.23 KFP03163.1 - 6.9e-43 147.3 1.9 8.7e-43 147.0 1.9 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Yae1_N PF09811.9 KFP03164.1 - 9.1e-15 54.1 53.5 0.43 10.3 1.1 5.5 1 1 1 2 2 2 1 Essential protein Yae1, N terminal Ig_3 PF13927.6 KFP03165.1 - 8.2e-30 103.2 13.2 7.2e-08 32.9 0.1 6.5 5 2 1 6 6 6 6 Immunoglobulin domain C2-set_2 PF08205.12 KFP03165.1 - 1.8e-25 88.8 2.5 5.6e-19 68.0 0.0 4.4 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 KFP03165.1 - 2.8e-25 88.5 8.8 3.6e-07 30.4 0.1 5.1 6 0 0 6 6 6 4 Immunoglobulin domain ig PF00047.25 KFP03165.1 - 2.5e-16 59.6 14.0 0.0013 18.9 0.5 7.3 5 3 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 KFP03165.1 - 2e-15 56.6 16.3 0.0014 18.7 0.1 7.9 5 3 0 6 6 6 4 Immunoglobulin I-set domain V-set PF07686.17 KFP03165.1 - 1.8e-09 37.7 11.9 0.0019 18.4 0.0 7.1 4 3 1 6 6 6 2 Immunoglobulin V-set domain C1-set PF07654.15 KFP03165.1 - 4.7e-07 30.1 10.1 0.00071 19.9 0.1 5.0 4 2 1 6 6 6 2 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFP03165.1 - 0.00055 19.4 0.0 0.14 11.8 0.0 3.0 3 0 0 3 3 3 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFP03165.1 - 0.0058 16.7 0.3 1 9.5 0.0 3.5 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain CD34_antigen PF06365.12 KFP03165.1 - 0.02 14.5 0.0 0.04 13.5 0.0 1.6 1 0 0 1 1 1 0 CD34/Podocalyxin family Amnionless PF14828.6 KFP03165.1 - 0.031 13.1 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 Amnionless PepSY_TM PF03929.16 KFP03165.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 PepSY-associated TM region Cbl_N PF02262.16 KFP03166.1 - 3e-47 159.7 1.7 5.5e-47 158.9 1.7 1.5 1 0 0 1 1 1 1 CBL proto-oncogene N-terminal domain 1 Cbl_N3 PF02762.14 KFP03166.1 - 4.8e-45 151.3 0.0 8.3e-45 150.6 0.0 1.4 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain Cbl_N2 PF02761.14 KFP03166.1 - 3.7e-40 136.5 1.3 7.2e-40 135.6 1.3 1.5 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain Prok-RING_4 PF14447.6 KFP03166.1 - 2.4e-13 49.7 9.0 5.2e-13 48.6 9.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFP03166.1 - 4.7e-11 42.4 8.0 1.1e-10 41.2 8.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP03166.1 - 1.4e-08 34.4 7.4 1.4e-08 34.4 7.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP03166.1 - 2.8e-08 34.0 7.5 2.8e-08 34.0 7.5 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP03166.1 - 6.4e-05 22.7 8.0 6.4e-05 22.7 8.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP03166.1 - 0.00068 19.6 5.2 0.00068 19.6 5.2 2.4 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP03166.1 - 0.0032 17.4 10.3 0.0088 16.0 10.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFP03166.1 - 0.017 15.3 8.0 0.049 13.8 8.0 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KFP03166.1 - 0.71 9.5 7.7 1.8 8.3 7.7 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KFP03166.1 - 0.78 10.1 12.5 0.047 14.0 7.2 1.8 2 0 0 2 2 1 0 RING-H2 zinc finger domain zf-UDP PF14569.6 KFP03166.1 - 0.87 9.8 6.1 2.5 8.3 6.1 1.8 1 1 0 1 1 1 0 Zinc-binding RING-finger DUF2028 PF09667.10 KFP03167.1 - 3.1e-62 210.1 9.9 1.2e-61 208.1 9.9 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF2028) HMG_box PF00505.19 KFP03167.1 - 3.2e-17 62.7 0.8 9.7e-17 61.2 0.8 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP03167.1 - 4.8e-11 43.1 0.7 1.7e-10 41.3 0.7 2.0 1 0 0 1 1 1 1 HMG-box domain CD47 PF04549.14 KFP03168.1 - 3.5e-41 140.8 26.2 4.7e-41 140.4 26.2 1.2 1 0 0 1 1 1 1 CD47 transmembrane region V-set_CD47 PF08204.11 KFP03168.1 - 1e-34 119.3 0.0 1.6e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 CD47 immunoglobulin-like domain Baculo_p74 PF04583.12 KFP03168.1 - 1 8.8 0.0 1 8.8 0.0 2.5 3 0 0 3 3 3 0 Baculoviridae p74 conserved region Claudin_2 PF13903.6 KFP03168.1 - 3.4 7.4 12.1 1.5 8.6 4.3 2.3 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction IFT57 PF10498.9 KFP03169.1 - 4.7e-135 450.2 4.4 5.4e-135 450.0 4.4 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 TPR_MLP1_2 PF07926.12 KFP03169.1 - 0.015 15.4 3.3 0.015 15.4 3.3 3.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein MCPsignal PF00015.21 KFP03169.1 - 0.019 14.8 0.4 0.05 13.4 0.3 1.7 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Lipoprotein_20 PF13942.6 KFP03169.1 - 0.059 13.3 5.1 0.16 11.8 0.7 2.6 2 1 1 3 3 3 0 YfhG lipoprotein Glyco_transf_25 PF01755.17 KFP03169.1 - 0.13 12.1 3.7 0.19 11.5 0.9 2.2 2 0 0 2 2 2 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Mod_r PF07200.13 KFP03169.1 - 0.88 9.7 15.2 0.19 11.8 4.3 3.0 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Med9 PF07544.13 KFP03169.1 - 1.2 9.3 6.3 0.19 11.8 1.1 2.3 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Prominin PF05478.11 KFP03169.1 - 1.8 6.4 8.0 0.41 8.5 4.4 1.6 1 1 0 1 1 1 0 Prominin DUF4407 PF14362.6 KFP03169.1 - 1.8 7.8 7.8 0.33 10.3 1.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 KFP03169.1 - 6.1 7.2 19.6 0.25 11.8 9.7 2.6 1 1 1 2 2 2 0 Fez1 Spc7 PF08317.11 KFP03169.1 - 7.4 5.4 22.1 0.024 13.5 10.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Myosin_head PF00063.21 KFP03170.1 - 2.1e-286 951.6 0.1 2.1e-286 951.6 0.1 2.9 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KFP03170.1 - 3.7e-161 538.3 266.4 4.4e-161 538.1 266.4 1.0 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 KFP03170.1 - 2.7e-16 59.1 3.6 7.5e-16 57.7 3.6 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Filament PF00038.21 KFP03170.1 - 0.00083 19.0 48.0 0.00083 19.0 48.0 8.1 1 1 6 8 8 8 5 Intermediate filament protein DUF1664 PF07889.12 KFP03170.1 - 0.069 13.2 147.2 0.053 13.6 8.6 13.8 2 2 12 15 15 15 0 Protein of unknown function (DUF1664) AAA_22 PF13401.6 KFP03170.1 - 0.071 13.4 0.0 0.071 13.4 0.0 5.8 4 2 1 5 5 5 0 AAA domain AAA_16 PF13191.6 KFP03170.1 - 0.24 11.8 0.0 0.24 11.8 0.0 5.8 3 2 0 4 4 4 0 AAA ATPase domain SH2 PF00017.24 KFP03171.1 - 5.3e-15 55.3 0.4 7.2e-15 54.9 0.4 1.2 1 0 0 1 1 1 1 SH2 domain Repressor_Mnt PF11423.8 KFP03171.1 - 0.12 12.2 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Regulatory protein Mnt SIT PF15330.6 KFP03172.1 - 2.9e-24 85.7 0.5 4.8e-24 85.0 0.5 1.4 1 0 0 1 1 1 1 SHP2-interacting transmembrane adaptor protein, SIT Brr6_like_C_C PF10104.9 KFP03172.1 - 0.075 12.8 0.3 0.11 12.2 0.3 1.3 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain EF-hand_7 PF13499.6 KFP03173.1 - 5.6e-09 36.3 4.1 0.0001 22.6 0.1 1.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFP03173.1 - 8.5e-07 28.1 0.8 2.2e-06 26.8 0.4 1.9 1 1 1 2 2 2 1 EF hand EF-hand_5 PF13202.6 KFP03173.1 - 8.9e-07 28.1 1.0 2.3e-06 26.8 0.2 2.0 1 1 1 2 2 2 1 EF hand EF-hand_8 PF13833.6 KFP03173.1 - 4.3e-06 26.5 0.1 5.9e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP03173.1 - 2.8e-05 23.7 0.2 8.8e-05 22.1 0.1 1.8 1 1 1 2 2 2 1 EF-hand domain Importin_rep_3 PF18806.1 KFP03173.1 - 0.032 14.3 0.1 1.6 8.8 0.0 2.7 1 1 2 3 3 3 0 Importin 13 repeat C2-set_2 PF08205.12 KFP03176.1 - 2.4e-17 62.8 0.0 6.7e-17 61.4 0.0 1.7 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 KFP03176.1 - 1.8e-11 44.5 0.2 1.9e-07 31.5 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP03176.1 - 3.5e-09 36.7 0.0 3.8e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP03176.1 - 9.4e-08 32.3 0.0 0.00015 22.0 0.1 2.5 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP03176.1 - 0.00065 19.7 0.1 0.041 14.0 0.1 2.6 2 1 0 2 2 2 1 Immunoglobulin I-set domain Ig_6 PF18452.1 KFP03176.1 - 0.0074 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain C1-set PF07654.15 KFP03176.1 - 0.055 13.8 0.0 2.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin C1-set domain V-set PF07686.17 KFP03177.1 - 4.2e-09 36.5 0.5 0.0002 21.5 0.1 2.5 2 1 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.25 KFP03177.1 - 0.0067 16.6 0.1 5.3 7.3 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP03177.1 - 0.018 15.1 0.0 0.05 13.7 0.0 1.8 2 0 0 2 2 2 0 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP03177.1 - 0.065 13.8 0.2 3.6 8.2 0.0 2.4 2 1 0 2 2 2 0 Immunoglobulin domain PI-PLC-X PF00388.19 KFP03178.1 - 0.01 15.5 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain PH PF00169.29 KFP03179.1 - 1.1e-13 51.6 0.2 3.2e-13 50.1 0.2 1.9 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFP03179.1 - 0.00098 19.4 0.1 0.0027 17.9 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFP03179.1 - 0.0012 19.3 0.6 0.0061 17.0 0.6 2.4 1 0 0 1 1 1 1 Pleckstrin homology domain Abhydrolase_1 PF00561.20 KFP03180.1 - 1.3e-12 47.9 0.0 2.7e-11 43.6 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFP03180.1 - 4.6e-11 42.4 0.0 8.6e-07 28.5 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFP03180.1 - 7.5e-09 35.4 0.0 1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KFP03180.1 - 5.6e-08 33.7 0.0 1.8e-07 32.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2920 PF11144.8 KFP03180.1 - 0.0065 15.7 0.0 0.033 13.4 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2920) UPF0227 PF05728.12 KFP03180.1 - 0.008 16.1 0.0 0.059 13.3 0.0 2.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) Ser_hydrolase PF06821.13 KFP03180.1 - 0.018 14.9 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_2 PF02230.16 KFP03180.1 - 0.062 13.1 0.0 4.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase BAAT_C PF08840.11 KFP03180.1 - 0.11 12.3 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF515 PF04415.12 KFP03180.1 - 0.12 10.8 0.1 0.17 10.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) CH PF00307.31 KFP03181.1 - 1.2e-21 77.0 0.0 1.6e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 KFP03181.1 - 2.4e-14 52.6 6.4 2.4e-14 52.6 6.4 1.8 2 0 0 2 2 2 1 Calponin family repeat Trypsin PF00089.26 KFP03182.1 - 7e-65 218.9 0.3 1.3e-64 218.0 0.3 1.5 1 0 0 1 1 1 1 Trypsin SEA PF01390.20 KFP03182.1 - 5.5e-20 71.4 0.6 9.7e-20 70.7 0.6 1.4 1 0 0 1 1 1 1 SEA domain Ldl_recept_a PF00057.18 KFP03182.1 - 7e-20 71.0 38.5 2.8e-09 37.0 6.1 3.9 2 1 1 3 3 3 3 Low-density lipoprotein receptor domain class A CUB PF00431.20 KFP03182.1 - 1.3e-11 44.8 0.6 2.6e-05 24.5 0.5 3.2 2 1 0 2 2 2 2 CUB domain DUF1986 PF09342.11 KFP03182.1 - 0.0035 17.7 0.1 0.016 15.6 0.1 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 KFP03182.1 - 0.005 17.8 0.0 0.01 16.7 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain V-set PF07686.17 KFP03184.1 - 4.5e-07 30.0 0.0 5.2e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFP03184.1 - 9.9e-05 22.4 0.0 0.00016 21.8 0.0 1.4 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFP03184.1 - 0.00032 21.2 0.0 0.0005 20.6 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP03184.1 - 0.00058 19.9 0.0 0.00092 19.2 0.0 1.2 1 1 0 1 1 1 1 Immunoglobulin I-set domain Antimicrobial_4 PF08024.11 KFP03184.1 - 0.17 12.0 0.5 0.38 10.8 0.5 1.5 1 0 0 1 1 1 0 Ant antimicrobial peptide ig PF00047.25 KFP03185.1 - 1.2e-18 67.0 6.5 3.5e-13 49.5 1.2 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 KFP03185.1 - 1.4e-13 51.2 5.9 1e-07 32.4 0.3 2.4 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP03185.1 - 2.8e-11 43.3 1.0 2.5e-06 27.5 0.1 2.4 2 1 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 KFP03185.1 - 3e-10 40.2 0.5 6.6e-10 39.1 0.5 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP03185.1 - 1.3e-08 34.8 1.0 1.1e-05 25.4 0.2 2.3 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 KFP03185.1 - 5.9e-05 23.3 5.5 0.0093 16.3 0.9 2.7 2 1 0 2 2 2 2 Immunoglobulin domain Lep_receptor_Ig PF06328.11 KFP03185.1 - 0.0031 17.4 4.8 0.46 10.5 0.2 2.7 2 1 0 2 2 2 2 Ig-like C2-type domain Ig_6 PF18452.1 KFP03185.1 - 0.01 15.4 0.2 0.01 15.4 0.2 2.2 3 0 0 3 3 3 1 Immunoglobulin domain AKAP95 PF04988.12 KFP03186.1 - 0.00011 22.5 0.5 0.00016 22.0 0.5 1.4 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.7 KFP03186.1 - 0.0031 17.8 1.4 0.0043 17.4 0.8 1.5 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Mut7-C PF01927.16 KFP03186.1 - 0.012 15.7 1.6 0.41 10.7 0.2 2.2 1 1 1 2 2 2 0 Mut7-C RNAse domain HV_small_capsid PF17086.5 KFP03186.1 - 0.063 13.6 0.1 0.18 12.1 0.0 1.8 1 1 1 2 2 2 0 Small capsid protein of Herpesviridae ADD_ATRX PF17981.1 KFP03186.1 - 0.14 12.1 0.1 0.14 12.1 0.1 1.7 2 0 0 2 2 2 0 Cysteine Rich ADD domain zf-C2H2_12 PF18658.1 KFP03186.1 - 0.23 11.0 1.4 0.37 10.4 0.2 1.9 2 1 1 3 3 3 0 Zinc-finger C2H2-type zf-met PF12874.7 KFP03186.1 - 2 8.9 6.0 38 4.9 6.0 2.5 1 1 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KFP03188.1 - 5.3e-08 32.9 39.2 0.022 15.2 1.9 6.2 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP03188.1 - 1.4e-05 25.5 44.0 0.026 15.3 2.6 7.5 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFP03188.1 - 0.0095 16.2 5.5 0.0095 16.2 5.5 4.6 3 1 1 4 4 4 1 C2H2-type zinc ribbon DUF1178 PF06676.11 KFP03188.1 - 0.035 14.5 8.0 1.2 9.5 2.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) zf-met PF12874.7 KFP03188.1 - 0.31 11.5 13.6 0.52 10.8 0.6 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type ARS2 PF04959.13 KFP03188.1 - 0.31 11.4 2.9 11 6.3 0.4 2.8 2 0 0 2 2 2 0 Arsenite-resistance protein 2 zf-BED PF02892.15 KFP03188.1 - 1.6 8.8 23.5 0.076 13.0 4.0 3.7 3 0 0 3 3 3 0 BED zinc finger zf-MYND PF01753.18 KFP03188.1 - 5.1 7.3 9.6 2 8.6 4.4 3.1 2 0 0 2 2 2 0 MYND finger zf-LYAR PF08790.11 KFP03188.1 - 7.8 6.5 8.6 18 5.3 0.1 4.0 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger DUF4518 PF15008.6 KFP03189.1 - 1e-107 359.4 0.1 1.2e-107 359.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) Ish1 PF10281.9 KFP03189.1 - 0.025 14.9 0.0 0.06 13.7 0.0 1.7 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein DUF1731 PF08338.11 KFP03190.1 - 3.5e-19 68.4 0.1 7e-19 67.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 KFP03190.1 - 2.2e-07 30.6 0.0 1.3e-06 28.1 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFP03190.1 - 0.0034 17.3 0.1 0.0068 16.3 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KFP03190.1 - 0.04 13.3 0.2 0.077 12.4 0.2 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase KR PF08659.10 KFP03190.1 - 0.16 11.9 0.2 17 5.3 0.0 2.2 1 1 1 2 2 2 0 KR domain Keratin PF02422.16 KFP03191.1 - 6.1e-35 118.8 13.6 6.6e-35 118.7 13.6 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFP03193.1 - 2e-27 94.7 13.0 2.2e-27 94.6 13.0 1.0 1 0 0 1 1 1 1 Keratin V-set PF07686.17 KFP03195.1 - 1e-08 35.3 0.1 1.2e-08 35.1 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP03195.1 - 0.0049 17.4 0.0 0.0064 17.1 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain NUMOD4 PF07463.11 KFP03195.1 - 0.0081 16.3 0.0 0.011 15.9 0.0 1.4 1 1 0 1 1 1 1 NUMOD4 motif I-set PF07679.16 KFP03195.1 - 0.094 12.8 0.0 0.15 12.1 0.0 1.4 1 1 0 1 1 1 0 Immunoglobulin I-set domain V-set PF07686.17 KFP03196.1 - 6.3e-09 36.0 0.1 7.2e-09 35.8 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP03196.1 - 0.0002 21.9 0.1 0.00025 21.6 0.1 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP03196.1 - 0.0055 16.7 0.0 0.0088 16.1 0.0 1.3 1 1 0 1 1 1 1 Immunoglobulin I-set domain C2-set_2 PF08205.12 KFP03196.1 - 0.025 14.6 0.2 0.027 14.5 0.2 1.1 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Keratin PF02422.16 KFP03197.1 - 5.5e-35 118.9 14.5 6e-35 118.8 14.5 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFP03199.1 - 5.5e-35 118.9 14.5 6e-35 118.8 14.5 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFP03201.1 - 2.3e-34 116.9 8.2 2.5e-34 116.8 8.2 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFP03204.1 - 4.3e-33 112.9 13.0 4.7e-33 112.8 13.0 1.0 1 0 0 1 1 1 1 Keratin V-set PF07686.17 KFP03206.1 - 5.1e-09 36.3 0.1 5.9e-09 36.1 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP03206.1 - 0.0054 17.3 0.0 0.007 16.9 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain NUMOD4 PF07463.11 KFP03206.1 - 0.0082 16.3 0.0 0.011 15.9 0.0 1.4 1 1 0 1 1 1 1 NUMOD4 motif I-set PF07679.16 KFP03206.1 - 0.1 12.7 0.0 0.16 12.0 0.0 1.4 1 1 0 1 1 1 0 Immunoglobulin I-set domain V-set PF07686.17 KFP03207.1 - 1.1e-08 35.3 0.1 1.2e-08 35.1 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP03207.1 - 0.0023 18.5 0.0 0.003 18.1 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP03207.1 - 0.033 14.2 0.0 0.053 13.6 0.0 1.4 1 1 0 1 1 1 0 Immunoglobulin I-set domain V-set PF07686.17 KFP03210.1 - 3.1e-08 33.7 0.0 3.6e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFP03210.1 - 0.0012 18.9 0.0 0.0019 18.2 0.0 1.3 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP03210.1 - 0.0025 18.4 0.0 0.0033 18.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP03210.1 - 0.12 12.7 0.0 0.29 11.5 0.0 1.7 1 1 0 1 1 1 0 Immunoglobulin domain Keratin PF02422.16 KFP03211.1 - 4.1e-31 106.5 19.3 4.5e-31 106.4 19.3 1.0 1 0 0 1 1 1 1 Keratin Rhomboid PF01694.22 KFP03212.1 - 3.6e-27 95.2 14.1 5.6e-27 94.6 14.1 1.3 1 0 0 1 1 1 1 Rhomboid family TMEM100 PF16311.5 KFP03212.1 - 0.19 11.3 0.6 0.48 10.0 0.6 1.7 1 0 0 1 1 1 0 Transmembrane protein 100 Caps_synth_CapC PF14102.6 KFP03212.1 - 1.3 9.4 7.4 0.3 11.5 3.8 1.9 2 0 0 2 2 2 0 Capsule biosynthesis CapC PMP22_Claudin PF00822.20 KFP03213.1 - 7.8e-32 110.4 11.6 9.6e-32 110.1 11.6 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP03213.1 - 6.1e-07 29.4 13.9 2e-06 27.7 13.9 1.9 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.12 KFP03213.1 - 0.00033 20.2 8.2 0.0087 15.6 0.7 2.1 1 1 1 2 2 2 2 Clc-like Amastin PF07344.11 KFP03213.1 - 0.0045 16.9 4.1 0.0045 16.9 4.1 2.0 1 1 1 2 2 2 1 Amastin surface glycoprotein DUF202 PF02656.15 KFP03213.1 - 6.8 7.2 10.1 16 6.0 2.5 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF4231 PF14015.6 KFP03213.1 - 9.8 6.7 7.1 1.9 9.0 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DSPc PF00782.20 KFP03214.1 - 5.7e-32 110.3 0.0 6.3e-32 110.2 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KFP03214.1 - 0.012 15.9 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 KFP03214.1 - 0.05 13.7 0.0 0.07 13.2 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Toxin_17 PF08086.11 KFP03214.1 - 0.05 13.9 0.4 0.099 12.9 0.4 1.4 1 0 0 1 1 1 0 Ergtoxin family LPD5 PF18799.1 KFP03214.1 - 0.052 14.0 0.0 0.058 13.8 0.0 1.1 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 5 DSPn PF14671.6 KFP03214.1 - 0.052 14.0 0.0 0.078 13.4 0.0 1.2 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half Y_phosphatase PF00102.27 KFP03214.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Glypican PF01153.19 KFP03215.1 - 6.8e-110 368.5 5.6 7.6e-110 368.3 5.6 1.0 1 0 0 1 1 1 1 Glypican Fz PF01392.22 KFP03215.1 - 0.052 14.2 0.8 0.052 14.2 0.8 2.2 2 0 0 2 2 2 0 Fz domain DUF577 PF04510.12 KFP03215.1 - 0.057 13.3 0.1 0.36 10.7 0.1 2.3 1 1 0 1 1 1 0 Family of unknown function (DUF577) Glypican PF01153.19 KFP03216.1 - 4.3e-204 679.4 5.4 4.8e-204 679.3 5.4 1.0 1 0 0 1 1 1 1 Glypican Fz PF01392.22 KFP03216.1 - 0.004 17.7 1.0 0.014 16.0 1.0 1.9 1 0 0 1 1 1 1 Fz domain CBS PF00571.28 KFP03217.1 - 8.8e-33 112.5 3.3 2.6e-09 37.4 0.5 4.3 4 0 0 4 4 4 4 CBS domain Cbl_N3 PF02762.14 KFP03217.1 - 0.098 12.5 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain IF-2 PF11987.8 KFP03217.1 - 0.11 12.6 0.4 0.21 11.7 0.4 1.3 1 0 0 1 1 1 0 Translation-initiation factor 2 Glycos_transf_2 PF00535.26 KFP03218.1 - 4.6e-31 107.9 0.0 7.6e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFP03218.1 - 6.9e-22 78.0 1.9 1e-21 77.5 1.9 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 KFP03218.1 - 8.2e-07 29.1 0.0 1.3e-05 25.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KFP03218.1 - 7.8e-05 22.3 0.0 0.00019 21.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.6 KFP03218.1 - 0.0028 18.4 0.3 3.4 8.5 0.1 2.5 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Glyco_tranf_2_2 PF10111.9 KFP03218.1 - 0.025 14.1 0.0 0.047 13.2 0.0 1.5 1 1 0 1 1 1 0 Glycosyltransferase like family 2 PHD PF00628.29 KFP03219.1 - 5e-36 122.4 141.9 8.5e-10 38.4 6.9 10.4 7 2 3 10 10 10 6 PHD-finger FYRC PF05965.14 KFP03219.1 - 1.6e-25 89.0 0.0 9.3e-25 86.6 0.0 2.5 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 KFP03219.1 - 1.4e-19 69.7 0.0 2.6e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus SET PF00856.28 KFP03219.1 - 4e-18 66.4 0.3 4e-18 66.4 0.3 4.6 5 0 0 5 5 5 1 SET domain zf-HC5HC2H PF13771.6 KFP03219.1 - 2.1e-15 56.7 26.6 1.1e-09 38.5 9.2 10.2 5 2 5 10 10 10 3 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFP03219.1 - 5.1e-15 55.6 27.9 2.2e-10 40.7 8.9 9.2 3 2 5 8 8 8 3 PHD-zinc-finger like domain HMG_box PF00505.19 KFP03219.1 - 0.00013 22.3 0.2 0.00013 22.3 0.2 2.6 2 0 0 2 2 2 1 HMG (high mobility group) box Rad51 PF08423.11 KFP03220.1 - 2.2e-18 66.5 0.0 2.6e-18 66.2 0.0 1.0 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KFP03220.1 - 0.0038 16.7 0.0 0.0068 15.9 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 KFP03220.1 - 0.06 12.9 0.0 0.29 10.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KFP03220.1 - 0.064 13.0 0.0 0.48 10.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 KFP03220.1 - 0.069 13.1 0.5 1.3 9.0 0.5 2.4 1 1 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KFP03220.1 - 0.1 13.0 0.0 0.21 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KFP03220.1 - 0.12 12.5 0.0 0.32 11.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain Actin PF00022.19 KFP03221.1 - 1.6e-86 290.5 0.0 2.1e-51 174.8 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 KFP03221.1 - 2e-05 23.6 0.0 0.038 12.8 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 KFP03221.1 - 0.0077 16.6 0.0 0.019 15.4 0.0 1.8 1 1 0 1 1 1 1 Cell division protein FtsA KilA-N PF04383.13 KFP03221.1 - 0.044 13.6 0.1 0.58 10.0 0.0 2.2 2 0 0 2 2 2 0 KilA-N domain Robl_LC7 PF03259.17 KFP03221.1 - 0.071 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Roadblock/LC7 domain Sec15 PF04091.12 KFP03222.1 - 2.2e-86 290.2 1.8 2.2e-86 290.2 1.8 1.5 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like AKAP7_NLS PF10469.9 KFP03222.1 - 0.025 14.5 1.1 0.058 13.3 1.1 1.6 1 0 0 1 1 1 0 AKAP7 2'5' RNA ligase-like domain L27_1 PF09058.10 KFP03222.1 - 0.025 14.5 0.3 0.13 12.3 0.3 2.3 2 0 0 2 2 2 0 L27_1 Mitovir_RNA_pol PF05919.11 KFP03222.1 - 0.067 12.3 0.5 0.1 11.8 0.5 1.2 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase adh_short PF00106.25 KFP03223.1 - 2e-14 53.5 0.0 2.9e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP03223.1 - 1.2e-08 34.8 0.0 1.3e-08 34.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Mtc PF03820.17 KFP03224.1 - 5.3e-114 380.5 0.2 5.9e-114 380.3 0.2 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier DUF1980 PF09323.10 KFP03224.1 - 0.048 13.6 0.1 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) RBD-FIP PF09457.10 KFP03225.1 - 7.4e-11 41.8 6.4 1.3e-10 41.0 6.4 1.4 1 0 0 1 1 1 1 FIP domain ATG16 PF08614.11 KFP03225.1 - 4.1 7.6 10.2 16 5.7 10.2 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Homeodomain PF00046.29 KFP03226.1 - 1.6e-22 79.1 4.7 2.2e-22 78.6 4.7 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP03226.1 - 0.053 13.4 0.7 0.094 12.6 0.1 1.8 2 0 0 2 2 2 0 Homeobox KN domain SET PF00856.28 KFP03227.1 - 1.1e-13 51.9 0.0 6.1e-13 49.5 0.0 2.1 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 KFP03227.1 - 0.00058 19.9 14.2 0.00058 19.9 14.2 2.9 2 2 0 2 2 2 1 MYND finger zf-HIT PF04438.16 KFP03227.1 - 2.1 8.3 13.7 0.065 13.1 4.9 2.6 2 0 0 2 2 2 0 HIT zinc finger PA PF02225.22 KFP03228.1 - 3.6e-06 26.9 0.0 5.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 PA domain MOSC PF03473.17 KFP03229.1 - 1.3e-24 86.7 0.0 1.4e-24 86.6 0.0 1.0 1 0 0 1 1 1 1 MOSC domain Homeodomain PF00046.29 KFP03231.1 - 3.1e-09 36.5 0.0 5.3e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Homeodomain DSPc PF00782.20 KFP03232.1 - 8.3e-42 142.2 0.6 1.9e-41 141.0 0.1 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 KFP03232.1 - 1.1e-14 54.9 0.0 2.9e-13 50.2 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain PTPlike_phytase PF14566.6 KFP03232.1 - 1e-05 25.7 0.0 2.2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KFP03232.1 - 9.1e-05 22.1 0.1 0.0024 17.5 0.0 2.2 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KFP03232.1 - 0.0023 18.2 0.6 0.017 15.4 0.0 2.6 3 0 0 3 3 3 1 Rit1 DUSP-like domain Herpes_UL7 PF01677.16 KFP03232.1 - 0.13 11.9 0.1 0.28 10.9 0.1 1.6 1 0 0 1 1 1 0 Herpesvirus UL7 like AAA_18 PF13238.6 KFP03232.1 - 0.13 12.8 0.0 6.1 7.4 0.0 2.3 1 1 1 2 2 2 0 AAA domain TAF1_subA PF14929.6 KFP03233.1 - 5.7e-124 414.3 16.3 6.5e-124 414.1 16.3 1.0 1 0 0 1 1 1 1 TAF RNA Polymerase I subunit A Apo-CIII PF05778.12 KFP03233.1 - 0.58 9.8 4.8 0.62 9.7 1.9 2.5 3 0 0 3 3 3 0 Apolipoprotein CIII (Apo-CIII) DUF4363 PF14276.6 KFP03233.1 - 2.7 8.2 7.2 79 3.4 3.5 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) NPIP PF06409.11 KFP03234.1 - 1.6e-12 47.1 17.3 1.5e-07 30.8 8.0 2.7 2 1 0 2 2 2 2 Nuclear pore complex interacting protein (NPIP) SH3_2 PF07653.17 KFP03234.1 - 1.1e-07 31.4 0.0 2.6e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain KELK PF15796.5 KFP03234.1 - 0.001 19.5 11.4 0.001 19.5 11.4 7.5 4 2 3 7 7 7 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase Aida_C2 PF14186.6 KFP03235.1 - 6.1e-65 217.3 0.3 8.2e-65 216.9 0.3 1.2 1 0 0 1 1 1 1 Cytoskeletal adhesion Aida_N PF08910.10 KFP03235.1 - 2e-22 79.5 1.2 3.7e-22 78.7 1.2 1.5 1 0 0 1 1 1 1 Aida N-terminus BRO1 PF03097.18 KFP03236.1 - 1e-40 139.8 0.4 1.3e-40 139.4 0.4 1.0 1 0 0 1 1 1 1 BRO1-like domain Patched PF02460.18 KFP03237.1 - 7.9e-18 63.9 38.8 1.6e-10 39.8 19.3 2.8 2 1 0 2 2 2 2 Patched family MMPL PF03176.15 KFP03237.1 - 6.6e-14 51.6 22.8 9.3e-09 34.7 7.1 2.3 2 0 0 2 2 2 2 MMPL family Sterol-sensing PF12349.8 KFP03237.1 - 4.7e-11 42.7 13.2 4.7e-11 42.7 13.2 2.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation RICTOR_M PF14666.6 KFP03237.1 - 0.18 11.6 0.7 1.6 8.5 0.1 2.6 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain DHR10 PF18595.1 KFP03237.1 - 2.7 8.1 8.5 0.51 10.4 1.4 2.6 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain ERM PF00769.19 KFP03238.1 - 1.9e-70 237.5 39.4 1.9e-70 237.5 39.4 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_C PF09380.10 KFP03238.1 - 6.3e-28 97.0 0.5 1.9e-27 95.4 0.0 2.1 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_M PF00373.18 KFP03238.1 - 6.3e-27 94.3 0.2 6.3e-27 94.3 0.2 3.3 2 1 1 3 3 3 1 FERM central domain FERM_N PF09379.10 KFP03238.1 - 9e-15 54.4 0.5 4.5e-14 52.1 0.1 2.4 2 0 0 2 2 2 1 FERM N-terminal domain C2 PF00168.30 KFP03239.1 - 9e-20 70.9 0.0 1.1e-17 64.1 0.1 2.5 2 0 0 2 2 2 1 C2 domain FYVE_2 PF02318.16 KFP03239.1 - 5.3e-18 65.4 12.0 5.3e-18 65.4 12.0 2.0 2 0 0 2 2 2 1 FYVE-type zinc finger PI3K_C2 PF00792.24 KFP03239.1 - 0.021 14.7 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 DOCK-C2 PF14429.6 KFP03239.1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins Tctex-1 PF03645.13 KFP03240.1 - 1.7e-33 115.0 0.6 1.8e-33 114.8 0.6 1.0 1 0 0 1 1 1 1 Tctex-1 family MIG-14_Wnt-bd PF06664.12 KFP03241.1 - 9.7e-94 313.9 35.2 9.7e-94 313.9 35.2 1.9 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion PSII_Ycf12 PF05969.11 KFP03241.1 - 5.9 7.0 6.4 2.4 8.2 0.1 2.8 2 1 0 2 2 2 0 Photosystem II complex subunit Ycf12 Tub PF01167.18 KFP03242.1 - 4.4e-30 105.2 0.3 2.6e-24 86.3 0.1 3.9 3 1 0 3 3 3 2 Tub family ANAPC4_WD40 PF12894.7 KFP03242.1 - 2.7e-08 34.0 1.6 0.00054 20.2 0.0 4.1 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain SOCS_box PF07525.16 KFP03242.1 - 0.00031 21.0 1.2 0.0009 19.5 1.2 1.8 1 0 0 1 1 1 1 SOCS box DUF3527 PF12043.8 KFP03242.1 - 0.085 12.4 0.1 0.085 12.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) Tfb5 PF06331.12 KFP03243.1 - 1.3e-29 102.0 0.2 1.4e-29 101.9 0.2 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 PGAP1 PF07819.13 KFP03244.1 - 9.9e-05 22.2 0.0 0.00035 20.4 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein HEAT_2 PF13646.6 KFP03244.1 - 0.018 15.4 0.3 7.9 6.9 0.0 2.5 2 0 0 2 2 2 0 HEAT repeats Abhydrolase_6 PF12697.7 KFP03244.1 - 0.053 14.1 0.0 0.13 12.9 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFP03244.1 - 0.094 12.0 0.0 0.32 10.2 0.0 1.9 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Syja_N PF02383.18 KFP03245.1 - 9.7e-64 215.7 0.1 2.4e-63 214.4 0.0 1.7 2 0 0 2 2 2 1 SacI homology domain DUF1866 PF08952.11 KFP03245.1 - 5e-55 185.4 0.0 1e-54 184.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1866) Exo_endo_phos PF03372.23 KFP03245.1 - 2.5e-13 50.1 0.0 4.5e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RRM_1 PF00076.22 KFP03245.1 - 0.0025 17.6 0.2 0.0078 16.0 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BAR_3_WASP_bdg PF10456.9 KFP03246.1 - 6e-113 376.1 0.4 7.7e-113 375.7 0.4 1.1 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.24 KFP03246.1 - 1.4e-23 83.0 0.2 3e-23 82.0 0.2 1.6 1 0 0 1 1 1 1 PX domain SH3_1 PF00018.28 KFP03246.1 - 1.2e-09 37.6 0.4 3.5e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFP03246.1 - 9.2e-09 35.0 0.2 2.4e-08 33.7 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KFP03246.1 - 5.7e-07 29.1 0.0 1.2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.10 KFP03246.1 - 0.0097 15.5 0.0 1.5 8.3 0.1 2.3 1 1 1 2 2 2 2 Vps5 C terminal like Yae1_N PF09811.9 KFP03247.1 - 1.5e-13 50.2 43.7 1.8e+04 -8.5 43.7 4.3 1 1 0 1 1 1 0 Essential protein Yae1, N terminal DUF1358 PF07096.11 KFP03248.1 - 1.1e-50 170.4 2.4 1.4e-50 170.1 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1358) BAF250_C PF12031.8 KFP03249.1 - 1.3e-121 404.7 0.0 2.4e-121 403.9 0.0 1.4 1 0 0 1 1 1 1 SWI/SNF-like complex subunit BAF250/Osa ARID PF01388.21 KFP03249.1 - 1.2e-17 64.3 0.0 2.9e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain NAD_binding_6 PF08030.12 KFP03252.1 - 8e-34 117.0 0.0 5.3e-33 114.4 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KFP03252.1 - 1.7e-26 92.8 1.7 3.5e-26 91.8 1.7 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFP03252.1 - 2.8e-23 82.1 0.0 6.2e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.24 KFP03252.1 - 5.9e-05 23.3 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain PDGLE PF13190.6 KFP03252.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 PDGLE domain NAD_binding_1 PF00175.21 KFP03252.1 - 0.11 13.1 0.0 1.1 10.0 0.0 2.3 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain RrnaAD PF00398.20 KFP03253.1 - 7.7e-41 139.9 0.0 9.7e-41 139.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PMP22_Claudin PF00822.20 KFP03254.1 - 1.3e-27 96.7 9.4 1.6e-27 96.4 9.4 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP03254.1 - 1.5e-08 34.7 8.6 3.8e-07 30.1 7.3 2.5 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction CD20 PF04103.15 KFP03254.1 - 0.15 12.1 8.8 0.055 13.6 3.0 2.5 3 0 0 3 3 3 0 CD20-like family RhoGEF PF00621.20 KFP03255.1 - 1.1e-26 94.2 0.7 1.1e-26 94.2 0.7 2.0 3 0 0 3 3 3 1 RhoGEF domain PH_10 PF15411.6 KFP03255.1 - 0.08 13.2 0.0 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain Stm1_N PF09598.10 KFP03255.1 - 0.082 13.8 0.5 0.24 12.3 0.5 1.8 1 0 0 1 1 1 0 Stm1 FadA PF09403.10 KFP03255.1 - 0.54 10.8 4.6 0.69 10.4 0.4 2.5 2 0 0 2 2 2 0 Adhesion protein FadA Tiam_CC_Ex PF18385.1 KFP03256.1 - 1.4e-55 185.7 0.1 2e-55 185.2 0.1 1.3 1 0 0 1 1 1 1 T-lymphoma invasion and metastasis CC-Ex domain PH PF00169.29 KFP03256.1 - 1e-08 35.6 0.2 3.6e-08 33.9 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 KFP03256.1 - 3.9e-07 30.5 0.0 1.1e-06 29.0 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 KFP03256.1 - 0.016 15.0 0.0 0.034 13.9 0.0 1.6 1 1 0 1 1 1 0 Pleckstrin homology domain Nup96 PF12110.8 KFP03256.1 - 0.026 13.6 0.1 0.039 13.1 0.1 1.2 1 0 0 1 1 1 0 Nuclear protein 96 DUF4660 PF15559.6 KFP03256.1 - 0.074 13.4 0.5 0.3 11.4 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4660) DUF1170 PF06663.13 KFP03257.1 - 1.4e-57 194.8 0.4 2.6e-57 194.0 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1170) CRIC_ras_sig PF10534.9 KFP03257.1 - 2.9e-37 126.7 0.1 7.2e-37 125.4 0.1 1.7 1 0 0 1 1 1 1 Connector enhancer of kinase suppressor of ras SAM_1 PF00536.30 KFP03257.1 - 1.2e-12 48.0 0.4 2.7e-12 47.0 0.4 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 KFP03257.1 - 3.6e-12 46.7 0.6 7e-12 45.8 0.6 1.5 1 0 0 1 1 1 1 PH domain PDZ PF00595.24 KFP03257.1 - 1.2e-09 38.3 0.0 2.8e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain SAM_2 PF07647.17 KFP03257.1 - 2.1e-08 34.2 0.5 4.8e-08 33.0 0.5 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ_6 PF17820.1 KFP03257.1 - 3.2e-07 30.1 0.3 1e-06 28.5 0.1 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KFP03257.1 - 0.001 19.3 0.0 0.0019 18.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain 7tm_1 PF00001.21 KFP03258.1 - 3.5e-58 197.0 25.3 4.4e-58 196.7 25.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFP03258.1 - 8.6e-09 35.2 15.0 1.1e-08 34.8 15.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 KFP03258.1 - 0.00026 20.7 22.8 0.00042 20.0 22.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP03258.1 - 0.0083 15.9 14.4 0.017 14.9 14.4 1.5 1 1 0 1 1 1 1 Olfactory receptor DUF2824 PF11039.8 KFP03258.1 - 0.0093 15.9 0.2 0.037 14.0 0.1 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2824) CitMHS PF03600.16 KFP03258.1 - 0.48 9.6 6.3 0.69 9.1 6.3 1.3 1 0 0 1 1 1 0 Citrate transporter RGS PF00615.19 KFP03260.1 - 5e-36 123.6 1.0 6.7e-36 123.1 1.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain F-box PF00646.33 KFP03261.1 - 3.4e-08 33.2 0.1 7.7e-08 32.0 0.1 1.6 1 0 0 1 1 1 1 F-box domain IBR PF01485.21 KFP03261.1 - 1.3e-06 28.5 10.0 3.5e-06 27.1 10.0 1.8 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain F-box-like PF12937.7 KFP03261.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 F-box-like Hormone_2 PF00123.20 KFP03262.1 - 2.2e-23 81.8 1.5 9.5e-12 44.6 0.2 2.4 2 0 0 2 2 2 2 Peptide hormone Oest_recep PF02159.15 KFP03263.1 - 7.8e-67 224.0 8.9 7.8e-67 224.0 8.9 1.8 2 0 0 2 2 2 1 Oestrogen receptor Hormone_recep PF00104.30 KFP03263.1 - 6.8e-34 117.3 3.6 1.1e-33 116.6 3.6 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFP03263.1 - 1.5e-31 108.7 13.9 2.6e-31 107.9 13.9 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) ESR1_C PF12743.7 KFP03263.1 - 1.7e-20 72.5 2.5 1.7e-20 72.5 2.5 2.2 2 0 0 2 2 2 1 Oestrogen-type nuclear receptor final C-terminal Thyroglob_assoc PF16597.5 KFP03263.1 - 0.045 14.1 0.2 0.094 13.0 0.2 1.5 1 0 0 1 1 1 0 Thyroglobulin_1 repeat associated disordered domain HAP1_N PF04849.13 KFP03264.1 - 0.00032 20.0 17.6 0.00032 20.0 17.6 5.7 2 2 0 4 4 4 1 HAP1 N-terminal conserved region Fib_alpha PF08702.10 KFP03264.1 - 0.0069 16.6 9.3 0.0069 16.6 9.3 6.3 2 1 4 7 7 7 2 Fibrinogen alpha/beta chain family SF3A3 PF16837.5 KFP03264.1 - 0.1 13.1 0.9 3.7 8.1 0.1 3.2 3 0 0 3 3 3 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 CIDE-N PF02017.15 KFP03264.1 - 0.13 12.3 0.1 0.13 12.3 0.1 3.0 3 0 0 3 3 3 0 CIDE-N domain ADIP PF11559.8 KFP03264.1 - 0.24 11.5 88.6 0.059 13.4 6.4 6.0 3 1 2 5 5 5 0 Afadin- and alpha -actinin-Binding AsiA PF09010.10 KFP03264.1 - 0.58 10.3 5.8 11 6.3 0.0 4.0 4 0 0 4 4 4 0 Anti-Sigma Factor A DUF89 PF01937.19 KFP03265.1 - 1e-119 399.6 0.3 1.2e-119 399.5 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 CLTH PF10607.9 KFP03265.1 - 0.043 13.7 2.0 1.1 9.2 2.0 2.5 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain DUF155 PF02582.14 KFP03266.1 - 2e-28 99.7 0.6 3.8e-28 98.8 0.6 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 BTB PF00651.31 KFP03267.1 - 4.3e-19 68.8 0.2 9e-19 67.8 0.2 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 KFP03267.1 - 3.2e-14 52.5 30.2 0.00023 21.5 1.5 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP03267.1 - 2.9e-12 46.4 19.9 0.00013 22.3 2.9 5.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP03267.1 - 3.2e-09 36.8 27.2 0.012 16.4 1.3 5.1 5 0 0 5 5 4 3 C2H2-type zinc finger zf-met PF12874.7 KFP03267.1 - 1.1e-08 35.1 21.9 0.16 12.4 1.5 4.8 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP03267.1 - 5.8e-07 29.6 16.6 0.014 15.7 0.1 4.7 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 KFP03267.1 - 0.0001 23.0 8.4 0.29 11.8 0.0 3.9 2 1 2 4 4 4 2 Zinc finger C2H2-type, 3 repeats zf-C2HE PF16278.5 KFP03267.1 - 0.036 14.5 15.9 6.2 7.3 0.1 4.5 3 1 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 KFP03267.1 - 0.038 14.0 30.5 0.74 9.9 0.5 4.8 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFP03267.1 - 0.098 12.6 19.0 0.36 10.8 0.4 4.3 4 0 0 4 4 4 0 zinc-finger of a C2HC-type FYVE PF01363.21 KFP03267.1 - 0.18 12.0 16.5 5.9 7.1 0.0 3.9 3 1 0 3 3 3 0 FYVE zinc finger zf-C2H2_2 PF12756.7 KFP03267.1 - 0.24 11.8 17.5 4.1 7.8 0.3 3.5 2 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-AN1 PF01428.16 KFP03267.1 - 1.3 9.3 21.7 0.31 11.2 2.7 4.7 4 1 0 4 4 4 0 AN1-like Zinc finger Zn-ribbon_8 PF09723.10 KFP03267.1 - 1.4 9.1 16.2 5 7.3 0.1 4.4 4 0 0 4 4 4 0 Zinc ribbon domain zf-CCHC_2 PF13696.6 KFP03267.1 - 3.6 7.5 15.9 10 6.0 2.2 3.7 3 0 0 3 3 3 0 Zinc knuckle zf_UBZ PF18439.1 KFP03267.1 - 5.4 6.7 12.4 24 4.6 0.4 4.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger WSK PF03832.13 KFP03270.1 - 4.2e-15 55.1 10.1 4e-13 48.8 2.3 3.9 4 0 0 4 4 4 2 WSK motif RhoGEF PF00621.20 KFP03271.1 - 1.7e-44 152.3 1.8 1.7e-44 152.3 1.8 2.2 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 KFP03271.1 - 0.0001 22.7 0.1 0.00036 21.0 0.1 2.0 1 1 0 1 1 1 1 PH domain PH_10 PF15411.6 KFP03271.1 - 0.016 15.5 0.1 0.016 15.5 0.1 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 KFP03271.1 - 0.042 13.8 0.1 0.16 11.9 0.1 2.0 1 0 0 1 1 1 0 PH domain SICA_alpha PF12887.7 KFP03271.1 - 0.095 12.6 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 SICA extracellular alpha domain Nitroreductase PF00881.24 KFP03272.1 - 7.9e-21 74.8 0.0 1.1e-20 74.4 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KFP03272.1 - 0.0004 20.0 0.0 1.4 8.4 0.0 3.1 2 1 0 2 2 2 2 Putative TM nitroreductase Ac110_PIF PF07280.11 KFP03272.1 - 0.1 12.4 0.1 0.26 11.1 0.1 1.7 1 0 0 1 1 1 0 Per os infectivity factor AC110 Ldl_recept_a PF00057.18 KFP03273.1 - 1.8e-07 31.3 11.3 3.9e-07 30.2 11.3 1.6 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A fn3_2 PF16893.5 KFP03273.1 - 0.07 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III domain Phage_TTP_1 PF04630.12 KFP03273.1 - 0.078 12.3 0.2 0.13 11.6 0.2 1.2 1 0 0 1 1 1 0 Phage tail tube protein DUF4625 PF15418.6 KFP03273.1 - 0.086 13.1 0.0 0.33 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4625) PCMT PF01135.19 KFP03274.1 - 2.9e-81 272.2 0.0 3.3e-81 272.0 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KFP03274.1 - 4.4e-07 30.5 0.0 7.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP03274.1 - 1.6e-06 28.0 0.0 3.4e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP03274.1 - 6.4e-05 23.5 0.1 0.00018 22.1 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFP03274.1 - 8e-05 22.1 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GCD14 PF08704.10 KFP03274.1 - 0.00011 22.0 0.0 0.00013 21.7 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PrmA PF06325.13 KFP03274.1 - 0.00014 21.4 0.0 0.00016 21.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KFP03274.1 - 0.0018 18.2 0.0 0.0055 16.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFP03274.1 - 0.026 14.1 0.1 0.037 13.6 0.1 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 KFP03274.1 - 0.073 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Fibrillarin PF01269.17 KFP03274.1 - 0.092 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin FtsJ PF01728.19 KFP03274.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 KFP03274.1 - 0.18 11.5 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase WD40 PF00400.32 KFP03275.1 - 6.6e-05 23.6 10.3 0.0022 18.8 0.1 4.8 6 1 1 7 7 7 2 WD domain, G-beta repeat Hira PF07569.11 KFP03275.1 - 0.059 13.1 0.3 18 5.0 0.0 3.1 2 1 1 4 4 4 0 TUP1-like enhancer of split PHTB1_N PF14727.6 KFP03275.1 - 0.08 12.3 0.0 1.8 7.8 0.0 2.3 2 1 0 2 2 2 0 PTHB1 N-terminus Pkinase PF00069.25 KFP03276.1 - 1.7e-61 207.9 0.4 1.5e-39 136.0 0.0 3.1 4 0 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFP03276.1 - 3e-28 98.8 0.0 5.3e-20 71.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase UBA PF00627.31 KFP03276.1 - 3.3e-09 36.5 2.5 4e-09 36.2 0.4 2.2 2 0 0 2 2 2 1 UBA/TS-N domain Haspin_kinase PF12330.8 KFP03276.1 - 0.00059 18.9 0.2 0.001 18.1 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFP03276.1 - 0.0036 16.6 0.1 0.024 13.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFP03276.1 - 0.0038 17.2 0.5 0.025 14.5 0.4 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family UBA_3 PF09288.10 KFP03276.1 - 0.038 13.8 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Pkinase_C PF00433.24 KFP03276.1 - 0.062 14.0 1.3 0.42 11.3 1.3 2.6 1 0 0 1 1 1 0 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.11 KFP03276.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HOIP-UBA PF16678.5 KFP03276.1 - 0.13 12.3 0.5 0.8 9.7 0.0 2.1 2 0 0 2 2 2 0 HOIP UBA domain pair Cas_Cas6 PF01881.16 KFP03276.1 - 0.21 12.1 2.8 0.42 11.2 2.8 1.4 1 0 0 1 1 1 0 CRISPR associated protein Cas6 AAA PF00004.29 KFP03277.1 - 1.1e-39 135.9 0.0 2.2e-39 134.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFP03277.1 - 1e-16 60.5 1.2 9.9e-16 57.3 1.2 2.7 1 1 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 KFP03277.1 - 5.7e-09 35.8 0.2 2.3e-08 33.9 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 KFP03277.1 - 6.4e-06 26.4 0.1 1.8e-05 25.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KFP03277.1 - 1.3e-05 25.0 0.0 5.5e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KFP03277.1 - 5e-05 23.5 0.0 0.00015 21.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFP03277.1 - 0.00054 20.0 0.3 0.004 17.2 0.3 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KFP03277.1 - 0.0011 18.3 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KFP03277.1 - 0.0016 18.2 0.0 0.0082 15.9 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 KFP03277.1 - 0.0018 18.3 0.0 0.0055 16.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 KFP03277.1 - 0.0033 16.8 0.0 0.0075 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KFP03277.1 - 0.0043 17.5 0.1 0.011 16.1 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KFP03277.1 - 0.0045 16.5 0.2 0.012 15.2 0.2 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region TsaE PF02367.17 KFP03277.1 - 0.0062 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KFP03277.1 - 0.0065 16.7 1.4 0.08 13.2 0.4 3.0 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 KFP03277.1 - 0.0076 15.6 0.5 1.2 8.5 0.1 2.6 2 1 1 3 3 2 1 KaiC PhoH PF02562.16 KFP03277.1 - 0.023 14.2 0.1 0.054 12.9 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 KFP03277.1 - 0.025 15.1 0.8 0.16 12.5 0.8 2.4 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KFP03277.1 - 0.038 13.8 1.3 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFP03277.1 - 0.064 13.8 0.0 0.4 11.2 0.0 2.2 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 KFP03277.1 - 0.07 13.5 0.8 0.17 12.3 0.0 2.2 2 1 0 2 2 1 0 RNA helicase TPR_8 PF13181.6 KFP03277.1 - 0.15 12.3 0.8 0.52 10.7 0.1 2.3 2 0 0 2 2 1 0 Tetratricopeptide repeat Sigma54_activat PF00158.26 KFP03277.1 - 0.16 11.7 0.0 0.52 10.0 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.6 KFP03277.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TPR_1 PF00515.28 KFP03277.1 - 0.17 11.8 0.2 0.57 10.1 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat AAA_24 PF13479.6 KFP03277.1 - 0.19 11.4 1.8 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.21 KFP03277.1 - 0.2 11.3 1.8 1 9.0 0.0 2.8 3 0 0 3 3 3 0 Guanylate kinase TPR_2 PF07719.17 KFP03277.1 - 0.34 11.1 1.7 1.2 9.4 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Yae1_N PF09811.9 KFP03279.1 - 1.9e-11 43.4 34.3 3.5e+02 1.0 34.3 3.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Pro_isomerase PF00160.21 KFP03280.1 - 4.9e-31 108.1 0.2 4.9e-31 108.1 0.2 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KFP03280.1 - 5.3e-18 64.6 0.0 1.1e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_Zc3h12a PF11977.8 KFP03281.1 - 2.1e-63 212.8 0.0 2.9e-63 212.3 0.0 1.2 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain UBA_6 PF18039.1 KFP03281.1 - 7.9e-20 70.5 0.1 1.4e-19 69.7 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain zf-CCCH_4 PF18044.1 KFP03281.1 - 1.5e-05 24.7 5.5 1.5e-05 24.7 5.5 1.9 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 KFP03281.1 - 0.006 16.5 5.9 0.013 15.4 4.0 2.4 1 1 1 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PRORP PF16953.5 KFP03281.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein-only RNase P zf-CCCH_2 PF14608.6 KFP03281.1 - 0.11 13.0 9.6 0.25 11.9 9.6 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Omega-toxin PF06357.11 KFP03281.1 - 0.37 10.6 3.7 0.78 9.6 3.7 1.5 1 0 0 1 1 1 0 Omega-atracotoxin zf_CCCH_4 PF18345.1 KFP03281.1 - 4.2 7.5 8.5 1.5 9.0 4.4 2.4 2 1 1 3 3 3 0 Zinc finger domain CUE PF02845.16 KFP03282.1 - 3.4e-09 36.2 0.3 6.2e-09 35.4 0.3 1.4 1 0 0 1 1 1 1 CUE domain zf-RanBP PF00641.18 KFP03282.1 - 1.4e-05 24.3 2.0 3.3e-05 23.1 2.0 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Spc29 PF17082.5 KFP03282.1 - 0.0012 18.7 1.4 0.0038 17.1 1.4 1.9 1 0 0 1 1 1 1 Spindle Pole Component 29 DivIC PF04977.15 KFP03282.1 - 0.059 13.2 3.3 0.52 10.1 2.8 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF1640 PF07798.11 KFP03282.1 - 0.36 10.9 4.6 0.74 9.8 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) XhlA PF10779.9 KFP03282.1 - 2.7 8.3 4.6 4.7 7.5 4.6 1.3 1 0 0 1 1 1 0 Haemolysin XhlA SlyX PF04102.12 KFP03282.1 - 2.8 8.6 5.8 3 8.5 3.8 2.1 1 1 1 2 2 2 0 SlyX 7tm_2 PF00002.24 KFP03283.1 - 1.2e-80 270.4 19.8 1.5e-80 270.0 19.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFP03283.1 - 1.6e-18 66.8 8.0 3.1e-18 65.8 8.0 1.5 1 0 0 1 1 1 1 Hormone receptor domain DUF4034 PF13226.6 KFP03283.1 - 0.082 12.3 0.4 0.15 11.4 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4034) DUF2070 PF09843.9 KFP03283.1 - 1.9 6.6 10.0 2.9 6.1 10.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PID PF00640.23 KFP03284.1 - 2e-30 105.6 0.5 3e-30 105.1 0.5 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFP03284.1 - 8.2e-12 45.4 0.3 1.5e-11 44.6 0.3 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.6 KFP03284.1 - 2e-05 24.6 0.0 2.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Ax_dynein_light PF10211.9 KFP03284.1 - 0.0019 18.2 0.4 0.003 17.5 0.4 1.3 1 0 0 1 1 1 1 Axonemal dynein light chain TSC22 PF01166.18 KFP03284.1 - 0.0027 18.0 1.7 0.0081 16.5 1.7 1.8 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF2004 PF09406.10 KFP03284.1 - 0.0036 17.6 0.2 0.013 15.8 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF2004) DivIC PF04977.15 KFP03284.1 - 0.0041 16.9 4.7 0.0072 16.1 4.7 1.3 1 0 0 1 1 1 1 Septum formation initiator bZIP_2 PF07716.15 KFP03284.1 - 0.0075 16.3 4.7 0.0075 16.3 4.7 1.6 2 0 0 2 2 1 1 Basic region leucine zipper ZapB PF06005.12 KFP03284.1 - 0.01 16.3 2.1 0.02 15.3 2.1 1.4 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_1 PF00170.21 KFP03284.1 - 0.012 15.7 2.0 0.022 14.9 2.0 1.4 1 0 0 1 1 1 0 bZIP transcription factor KASH_CCD PF14662.6 KFP03284.1 - 0.013 15.4 0.6 0.023 14.5 0.6 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Pox_A_type_inc PF04508.12 KFP03284.1 - 0.016 15.1 2.9 0.097 12.6 0.2 2.6 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat DUF4337 PF14235.6 KFP03284.1 - 0.019 15.1 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) HAP1_N PF04849.13 KFP03284.1 - 0.021 14.1 0.3 0.029 13.6 0.3 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Cnn_1N PF07989.11 KFP03284.1 - 0.025 14.7 0.6 0.052 13.7 0.6 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Spc24 PF08286.11 KFP03284.1 - 0.045 14.0 0.5 0.096 12.9 0.5 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 BST2 PF16716.5 KFP03284.1 - 0.054 14.1 1.9 0.13 12.9 1.9 1.6 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 Herpes_UL6 PF01763.16 KFP03284.1 - 0.054 12.0 0.2 0.091 11.3 0.2 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like GIT_CC PF16559.5 KFP03284.1 - 0.079 12.8 0.5 0.079 12.8 0.5 1.8 2 0 0 2 2 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor APG6_N PF17675.1 KFP03284.1 - 0.09 13.3 1.7 0.17 12.4 1.7 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 KFP03284.1 - 0.11 13.1 1.6 0.29 11.8 1.6 1.7 1 0 0 1 1 1 0 SlyX CCD48 PF15799.5 KFP03284.1 - 0.16 10.3 0.6 0.28 9.4 0.6 1.3 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 48 TMF_DNA_bd PF12329.8 KFP03284.1 - 0.59 10.2 6.7 0.11 12.5 2.8 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding COLFI PF01410.18 KFP03285.1 - 2.9e-54 183.9 0.0 3.1e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain COLFI PF01410.18 KFP03286.1 - 2.6e-53 180.7 0.1 2.8e-53 180.6 0.1 1.0 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain WD40 PF00400.32 KFP03287.1 - 7.7e-18 64.5 16.7 0.00051 20.8 0.2 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP03287.1 - 8e-07 29.3 0.2 1.4 9.2 0.0 5.7 3 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain FPN1 PF06963.12 KFP03288.1 - 6.1e-187 621.5 14.0 7e-187 621.3 14.0 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Vezatin PF12632.7 KFP03288.1 - 0.6 9.4 2.9 0.97 8.8 2.9 1.3 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes DUF347 PF03988.12 KFP03288.1 - 6.2 7.1 13.9 0.53 10.5 0.3 4.4 3 2 1 4 4 4 0 Repeat of Unknown Function (DUF347) Peptidase_M22 PF00814.25 KFP03289.1 - 2e-55 188.4 0.7 2.3e-55 188.2 0.7 1.0 1 0 0 1 1 1 1 Glycoprotease family stn_TNFRSF12A PF12191.8 KFP03289.1 - 0.038 14.2 0.8 0.078 13.2 0.1 1.7 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain ORMDL PF04061.14 KFP03290.1 - 6.1e-54 181.5 2.1 6.8e-54 181.4 2.1 1.0 1 0 0 1 1 1 1 ORMDL family DNA_mis_repair PF01119.19 KFP03291.1 - 1.2e-24 86.2 0.0 1.5e-23 82.8 0.0 2.5 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HMG_box PF00505.19 KFP03291.1 - 2.3e-15 56.8 3.6 2.3e-15 56.8 3.6 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HATPase_c_3 PF13589.6 KFP03291.1 - 4.7e-12 45.9 0.2 1.3e-11 44.5 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HMG_box_2 PF09011.10 KFP03291.1 - 1.1e-11 45.1 2.9 2.7e-11 43.9 2.9 1.6 1 0 0 1 1 1 1 HMG-box domain HATPase_c PF02518.26 KFP03291.1 - 1.1e-08 35.6 0.2 2.4e-08 34.5 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HMG_box_5 PF14887.6 KFP03291.1 - 0.001 19.0 2.0 0.0026 17.7 2.0 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box 5 CHDNT PF08073.12 KFP03291.1 - 0.0082 16.1 0.0 0.031 14.3 0.0 2.0 2 0 0 2 2 2 1 CHDNT (NUC034) domain IL5 PF02025.15 KFP03291.1 - 0.53 10.6 6.9 0.79 10.0 0.1 3.1 3 0 0 3 3 3 0 Interleukin 5 TGFb_propeptide PF00688.18 KFP03292.1 - 3.9e-34 118.5 0.0 4.9e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 KFP03292.1 - 1.7e-28 99.6 0.9 4.5e-28 98.3 0.9 1.7 1 0 0 1 1 1 1 Transforming growth factor beta like domain LydB PF16084.5 KFP03292.1 - 0.094 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 LydA-holin antagonist ECH_2 PF16113.5 KFP03293.1 - 1.1e-139 465.6 0.0 1.4e-139 465.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KFP03293.1 - 4.9e-33 114.5 0.0 1e-30 106.9 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Thioredox_DsbH PF03190.15 KFP03293.1 - 0.068 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 MFS_1_like PF12832.7 KFP03294.1 - 6.4e-93 311.7 10.0 8.6e-93 311.2 10.0 1.2 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFP03294.1 - 3.3e-30 105.2 24.1 5.8e-17 61.7 11.0 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KFP03294.1 - 1e-07 31.3 7.0 1e-07 31.3 7.0 3.6 3 1 0 3 3 3 1 Nucleoside H+ symporter LacY_symp PF01306.19 KFP03294.1 - 1.6e-06 27.2 18.7 0.0037 16.1 5.2 3.2 3 0 0 3 3 3 3 LacY proton/sugar symporter MFS_2 PF13347.6 KFP03294.1 - 9.7e-05 21.1 16.0 0.023 13.3 0.0 3.6 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.13 KFP03294.1 - 0.00071 18.1 1.7 0.00096 17.7 0.7 1.7 2 0 0 2 2 2 1 Transmembrane secretion effector SieB PF14163.6 KFP03294.1 - 0.17 11.4 0.5 2.3 7.7 0.0 2.6 2 0 0 2 2 2 0 Super-infection exclusion protein B OppC_N PF12911.7 KFP03294.1 - 4.1 7.4 12.6 4.4 7.4 0.1 4.0 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C Hamartin PF04388.12 KFP03294.1 - 5.1 5.6 6.6 9.6 4.7 6.6 1.4 1 0 0 1 1 1 0 Hamartin protein NEMP PF10225.9 KFP03295.1 - 1.7e-79 267.0 6.1 2.2e-79 266.6 6.1 1.2 1 0 0 1 1 1 1 NEMP family DUF5381 PF17353.2 KFP03295.1 - 4.2 7.1 8.2 11 5.7 4.8 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5381) Nab1 PF04902.12 KFP03296.1 - 3.9e-58 196.8 0.0 7.7e-58 195.9 0.0 1.5 1 0 0 1 1 1 1 Conserved region in Nab1 NCD2 PF04905.13 KFP03296.1 - 2.4e-56 189.1 1.0 4e-56 188.4 1.0 1.3 1 0 0 1 1 1 1 NAB conserved region 2 (NCD2) NCD1 PF04904.13 KFP03296.1 - 2.8e-41 139.4 0.0 4.6e-41 138.7 0.0 1.3 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) tRNA-synt_1b PF00579.25 KFP03296.1 - 0.16 11.3 0.6 3.8 6.7 0.1 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Ribosomal_S3_C PF00189.20 KFP03297.1 - 2.8e-23 82.2 0.1 1e-22 80.4 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KFP03297.1 - 1.6e-11 43.9 0.1 2.5e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 KH domain SH3_1 PF00018.28 KFP03298.1 - 6.7e-26 89.6 1.4 2e-12 46.5 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KFP03298.1 - 7.5e-25 86.5 1.8 2.1e-13 49.9 0.2 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KFP03298.1 - 2.3e-21 75.2 0.2 5.4e-11 42.0 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 KFP03298.1 - 8.8e-05 22.7 0.3 8.8e-05 22.7 0.3 3.3 3 2 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain hSH3 PF14603.6 KFP03298.1 - 0.00097 19.5 0.1 0.0064 16.9 0.0 2.4 2 0 0 2 2 2 1 Helically-extended SH3 domain SH3_3 PF08239.11 KFP03298.1 - 0.0025 18.1 0.5 0.0058 16.9 0.1 1.9 2 0 0 2 2 2 1 Bacterial SH3 domain H-kinase_dim PF02895.14 KFP03298.1 - 0.064 13.7 2.8 5.3 7.5 0.1 3.7 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Vac14_Fab1_bd PF12755.7 KFP03298.1 - 0.093 13.3 1.4 0.28 11.8 0.4 2.2 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region 3H PF02829.14 KFP03298.1 - 0.098 13.0 1.6 0.36 11.2 0.0 2.7 3 2 0 3 3 3 0 3H domain Med21 PF11221.8 KFP03298.1 - 3.1 8.1 12.1 1.6 9.0 3.0 2.4 2 0 0 2 2 2 0 Subunit 21 of Mediator complex SseC PF04888.12 KFP03298.1 - 6.3 6.3 8.8 9.1 5.8 0.9 2.5 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family Pkinase PF00069.25 KFP03300.1 - 8.7e-44 149.9 0.0 1e-43 149.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP03300.1 - 3.8e-27 95.2 0.0 4.8e-27 94.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP03300.1 - 4e-05 23.1 0.0 5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFP03300.1 - 6e-05 23.1 0.5 0.11 12.4 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KFP03300.1 - 7.8e-05 22.1 0.1 0.00011 21.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFP03300.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Glyco_hydro_35 PF01301.19 KFP03301.1 - 7.7e-100 334.6 0.0 9.5e-100 334.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KFP03301.1 - 2.7e-10 40.8 0.1 5.4e-09 36.6 0.1 2.6 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Glyco_hydro_42 PF02449.15 KFP03301.1 - 1.2e-09 38.1 0.0 1.4e-08 34.5 0.0 2.0 1 1 0 1 1 1 1 Beta-galactosidase bVLRF1 PF18826.1 KFP03302.1 - 2.1e-51 173.7 0.0 5.2e-51 172.4 0.0 1.7 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor VATC PF18716.1 KFP03302.1 - 1.8e-19 69.3 2.3 1.8e-19 69.3 2.3 2.5 3 0 0 3 3 3 1 Vms1-associating treble clef domain Ank_5 PF13857.6 KFP03302.1 - 3.6e-08 33.5 0.5 5.2e-07 29.8 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP03302.1 - 2.9e-06 27.8 0.0 1.2e-05 25.8 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP03302.1 - 3.8e-05 23.7 0.1 0.00024 21.3 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 KFP03302.1 - 5.5e-05 23.4 0.1 0.00015 22.0 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 KFP03302.1 - 0.0049 17.4 0.1 0.15 12.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) zf-FCS PF06467.14 KFP03302.1 - 0.031 14.2 11.2 2.1 8.4 0.3 3.4 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif APG9 PF04109.16 KFP03303.1 - 1.6e-158 528.7 8.5 5.6e-158 526.9 8.5 1.8 1 1 0 1 1 1 1 Autophagy protein Apg9 EMP24_GP25L PF01105.24 KFP03303.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD MTABC_N PF16185.5 KFP03304.1 - 6.4e-43 147.0 5.0 1.6e-42 145.7 5.0 1.7 1 0 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region ABC_membrane PF00664.23 KFP03304.1 - 1.7e-39 136.1 12.3 2.6e-39 135.5 12.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFP03304.1 - 9.2e-35 120.1 0.0 1.6e-34 119.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFP03304.1 - 8.8e-07 28.6 0.1 8.2e-05 22.1 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFP03304.1 - 8.4e-05 23.0 0.0 0.00018 21.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFP03304.1 - 0.0009 19.5 0.0 0.0046 17.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KFP03304.1 - 0.0022 17.9 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KFP03304.1 - 0.0031 17.2 0.0 0.0076 16.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 KFP03304.1 - 0.0075 16.7 0.0 0.13 12.7 0.0 2.5 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 KFP03304.1 - 0.013 15.3 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 KFP03304.1 - 0.024 14.4 0.0 0.053 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Acyl-CoA_dh_1 PF00441.24 KFP03304.1 - 0.03 14.6 0.1 0.095 12.9 0.0 1.8 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Cytidylate_kin PF02224.18 KFP03304.1 - 0.039 13.7 0.1 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase AAA_30 PF13604.6 KFP03304.1 - 0.049 13.4 0.0 0.097 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KFP03304.1 - 0.049 12.9 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 KFP03304.1 - 0.057 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KFP03304.1 - 0.061 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain SbcCD_C PF13558.6 KFP03304.1 - 0.062 13.5 0.3 1.4 9.2 0.3 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 KFP03304.1 - 0.082 12.9 0.1 0.38 10.8 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KFP03304.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) zf-AN1 PF01428.16 KFP03305.1 - 1.4e-20 73.2 25.7 2.2e-12 46.9 10.5 2.9 2 1 1 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 KFP03305.1 - 0.039 14.3 16.4 0.5 10.8 2.9 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zinc_ribbon_4 PF13717.6 KFP03305.1 - 0.11 12.5 10.6 0.27 11.2 1.6 3.4 3 0 0 3 3 3 0 zinc-ribbon domain UCH_1 PF13423.6 KFP03305.1 - 1.1 8.8 4.9 1.3 8.5 4.9 1.0 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase IBR PF01485.21 KFP03305.1 - 4 7.7 25.9 23 5.3 16.8 3.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zinc-ribbons_6 PF07191.12 KFP03305.1 - 4.2 7.4 19.1 0.47 10.5 3.8 2.4 2 0 0 2 2 2 0 zinc-ribbons Reticulon PF02453.17 KFP03306.1 - 0.19 11.6 0.8 0.36 10.8 0.8 1.3 1 0 0 1 1 1 0 Reticulon Cyclin PF08613.11 KFP03307.1 - 2e-07 31.5 0.0 2.6e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KFP03307.1 - 3.9e-06 26.6 0.0 6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Xan_ur_permease PF00860.20 KFP03308.1 - 4.8e-63 213.2 23.7 6.3e-63 212.8 23.7 1.2 1 0 0 1 1 1 1 Permease family Bap31 PF05529.12 KFP03308.1 - 0.087 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region XLF PF09302.11 KFP03309.1 - 5.4e-34 117.9 0.0 8.4e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Hint PF01079.20 KFP03310.1 - 1.6e-60 204.3 0.0 1.4e-57 194.7 0.0 2.1 1 1 0 1 1 1 1 Hint module HH_signal PF01085.18 KFP03310.1 - 1e-49 168.3 0.3 1.3e-49 167.9 0.3 1.1 1 0 0 1 1 1 1 Hedgehog amino-terminal signalling domain Peptidase_M15_3 PF08291.11 KFP03310.1 - 0.0004 20.4 0.0 0.0006 19.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase M15 Homeodomain PF00046.29 KFP03311.1 - 1.6e-22 79.1 7.2 2.6e-22 78.4 7.2 1.3 1 0 0 1 1 1 1 Homeodomain QLQ PF08880.11 KFP03311.1 - 0.00097 18.8 0.4 0.0015 18.2 0.4 1.3 1 0 0 1 1 1 1 QLQ ASH PF15780.5 KFP03312.1 - 6.3e-37 125.7 0.6 1.7e-07 31.3 0.0 9.3 10 0 0 10 10 10 7 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 KFP03312.1 - 1.1e-15 57.4 0.0 0.047 13.5 0.0 8.3 8 0 0 8 8 8 4 MSP (Major sperm protein) domain TMEM131_like PF12371.8 KFP03312.1 - 5.1e-07 29.9 0.2 0.35 11.2 0.0 4.7 5 0 0 5 5 5 3 Transmembrane protein 131-like PapD-like PF14874.6 KFP03312.1 - 1.9e-05 24.8 0.7 4.2 7.6 0.0 5.7 6 0 0 6 6 6 2 Flagellar-associated PapD-like Crystall PF00030.19 KFP03313.1 - 3.9e-57 190.4 5.6 4.3e-28 97.3 0.8 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.13 KFP03313.1 - 0.0002 21.2 0.2 0.019 14.9 0.2 2.6 2 1 0 2 2 2 1 Peptidase inhibitor family I36 IL4_i_Ig PF18258.1 KFP03313.1 - 0.0003 20.9 2.7 0.29 11.4 0.3 3.6 2 2 2 4 4 4 3 Interleukin-4 inducing immunoglobulin-binding domain Ets PF00178.22 KFP03314.1 - 2.5e-36 124.0 0.4 3.4e-36 123.5 0.4 1.2 1 0 0 1 1 1 1 Ets-domain wnt PF00110.19 KFP03315.1 - 1.4e-123 412.4 20.7 1.6e-123 412.2 20.7 1.0 1 0 0 1 1 1 1 wnt family TTL PF03133.15 KFP03316.1 - 9.7e-102 340.0 0.1 1.5e-101 339.5 0.1 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KFP03316.1 - 4.9e-07 29.3 0.1 0.00026 20.3 0.0 2.9 2 2 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KFP03316.1 - 0.00093 18.5 0.0 0.0099 15.2 0.0 2.1 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp Pkinase PF00069.25 KFP03317.1 - 3e-77 259.6 0.0 4.4e-77 259.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP03317.1 - 1.8e-42 145.4 0.0 3e-42 144.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 KFP03317.1 - 3.7e-09 36.1 14.0 0.011 15.9 0.3 7.2 7 0 0 7 7 6 3 HEAT repeat HEAT_2 PF13646.6 KFP03317.1 - 2.3e-08 34.3 2.6 1.4e-06 28.6 2.5 3.5 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.6 KFP03317.1 - 7.4e-08 32.7 6.4 0.021 15.3 0.2 5.6 4 1 1 5 5 5 2 HEAT-like repeat Arm PF00514.23 KFP03317.1 - 9.8e-08 31.8 7.8 0.00016 21.6 0.3 5.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Haspin_kinase PF12330.8 KFP03317.1 - 0.0011 18.0 0.0 0.0022 17.0 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Cnd1 PF12717.7 KFP03317.1 - 0.0014 18.6 0.0 0.056 13.5 0.0 2.8 1 1 2 3 3 3 3 non-SMC mitotic condensation complex subunit 1 Kinase-like PF14531.6 KFP03317.1 - 0.0015 17.9 0.0 0.0032 16.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP03317.1 - 0.0039 16.0 0.0 0.0074 15.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP03317.1 - 0.005 16.8 5.6 0.01 15.8 0.1 3.5 3 1 1 4 4 4 1 Phosphotransferase enzyme family Adaptin_N PF01602.20 KFP03317.1 - 0.021 13.4 0.1 0.098 11.2 0.0 1.9 2 0 0 2 2 2 0 Adaptin N terminal region DUF4407 PF14362.6 KFP03317.1 - 0.032 13.6 0.1 0.055 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HEAT_PBS PF03130.16 KFP03317.1 - 0.055 14.2 3.7 2.1 9.3 0.1 4.0 3 0 0 3 3 2 0 PBS lyase HEAT-like repeat RIO1 PF01163.22 KFP03317.1 - 0.14 11.7 0.1 0.27 10.8 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 KFP03317.1 - 0.18 10.8 0.1 0.3 10.1 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RWD PF05773.22 KFP03318.1 - 6.1e-17 62.0 0.1 1.1e-16 61.1 0.1 1.4 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 KFP03318.1 - 1.7e-06 28.3 7.6 1.2e-05 25.6 7.6 2.2 1 1 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFP03318.1 - 6.7e-06 25.8 5.1 6.7e-06 25.8 5.1 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KFP03318.1 - 7.5e-05 22.6 8.0 0.00019 21.3 8.0 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFP03318.1 - 0.0045 16.8 7.3 0.0068 16.2 3.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP03318.1 - 0.0095 15.8 5.0 0.094 12.6 5.4 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP03318.1 - 0.025 14.6 7.1 0.029 14.4 1.1 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 KFP03318.1 - 0.21 11.6 4.9 0.39 10.8 1.7 2.3 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zf_RING PF16744.5 KFP03318.1 - 0.25 11.5 4.4 0.65 10.2 4.4 1.6 1 1 0 1 1 1 0 KIAA1045 RING finger BCS1_N PF08740.11 KFP03319.1 - 1.2e-44 152.5 1.3 1.7e-44 152.1 1.3 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KFP03319.1 - 2.8e-20 73.1 0.0 4.3e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFP03319.1 - 0.00059 20.3 0.1 0.002 18.6 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KFP03319.1 - 0.001 19.4 0.0 0.0024 18.2 0.0 1.7 1 1 0 1 1 1 1 RNA helicase DUF815 PF05673.13 KFP03319.1 - 0.0025 17.0 0.0 0.0042 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Rad17 PF03215.15 KFP03319.1 - 0.0063 16.4 0.0 0.021 14.7 0.0 1.7 1 1 1 2 2 2 1 Rad17 P-loop domain ABC_tran PF00005.27 KFP03319.1 - 0.0076 16.8 0.0 0.013 16.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KFP03319.1 - 0.013 15.2 0.1 0.073 12.8 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KFP03319.1 - 0.018 14.6 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KFP03319.1 - 0.02 14.9 0.0 0.048 13.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KFP03319.1 - 0.023 14.9 0.0 0.065 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KFP03319.1 - 0.093 13.0 0.0 0.91 9.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KFP03319.1 - 0.099 13.2 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KFP03319.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KFP03319.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KFP03319.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Polyoma_lg_T_C PF06431.11 KFP03319.1 - 0.16 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus MMR_HSR1 PF01926.23 KFP03319.1 - 0.21 11.7 0.0 0.73 9.9 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP03319.1 - 0.22 11.4 0.0 0.58 10.0 0.0 1.7 1 1 0 1 1 1 0 RsgA GTPase Rcd1 PF04078.13 KFP03320.1 - 1.2e-134 447.6 0.8 1.3e-134 447.4 0.8 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like UCH PF00443.29 KFP03321.1 - 5.4e-56 189.9 8.4 9.9e-56 189.1 8.4 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_N PF16674.5 KFP03321.1 - 1.1e-43 147.4 0.0 2.3e-43 146.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal of ubiquitin carboxyl-terminal hydrolase 37 UCH_1 PF13423.6 KFP03321.1 - 2e-10 40.8 21.4 1.3e-07 31.6 21.4 3.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UIM PF02809.20 KFP03321.1 - 2.2e-08 33.5 20.7 0.00025 20.7 0.2 3.8 3 0 0 3 3 3 3 Ubiquitin interaction motif Peptidase_C98 PF15499.6 KFP03321.1 - 0.04 13.4 6.2 0.18 11.2 3.1 3.0 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Gelsolin PF00626.22 KFP03322.1 - 7e-100 327.0 0.1 4e-19 68.3 0.0 6.3 6 0 0 6 6 6 6 Gelsolin repeat VHP PF02209.19 KFP03322.1 - 4.6e-17 61.8 1.1 1e-16 60.7 1.1 1.7 1 0 0 1 1 1 1 Villin headpiece domain NIF PF03031.18 KFP03323.1 - 1.7e-49 167.6 0.0 2.2e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF3652 PF12372.8 KFP03323.1 - 0.2 11.6 1.5 0.79 9.7 1.5 2.1 1 1 0 1 1 1 0 Huntingtin protein region Nramp PF01566.18 KFP03324.1 - 4.5e-115 384.5 14.3 7.1e-115 383.8 14.3 1.3 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Lactamase_B PF00753.27 KFP03326.1 - 0.016 15.3 0.0 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Bax1-I PF01027.20 KFP03327.1 - 8.5e-28 97.6 25.4 1.4e-27 96.9 25.4 1.3 1 1 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Claudin_2 PF13903.6 KFP03327.1 - 0.09 12.5 4.3 0.24 11.1 0.7 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction BaxI_1 PF12811.7 KFP03327.1 - 0.31 10.6 13.9 0.037 13.6 7.6 2.0 2 0 0 2 2 2 0 Bax inhibitor 1 like LRRC37AB_C PF14914.6 KFP03327.1 - 0.86 9.5 4.2 0.26 11.2 1.2 1.6 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain DUF2070 PF09843.9 KFP03327.1 - 1 7.6 11.6 1.4 7.1 11.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CitMHS PF03600.16 KFP03327.1 - 5.3 6.1 17.3 7.8 5.6 17.1 1.4 1 1 0 1 1 1 0 Citrate transporter Wzy_C PF04932.15 KFP03327.1 - 10 5.8 11.4 13 5.4 3.6 3.1 2 1 0 2 2 2 0 O-Antigen ligase WD40 PF00400.32 KFP03328.1 - 4.5e-30 103.2 14.7 1.3e-05 25.8 0.2 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP03328.1 - 1.4e-20 73.4 1.7 1.9e-06 28.1 0.0 5.6 1 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP03328.1 - 1.9e-08 34.4 0.3 0.01 15.7 0.1 3.7 2 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KFP03328.1 - 2.6e-05 23.7 0.0 0.29 10.4 0.0 3.0 3 0 0 3 3 3 2 WD40-like domain PQQ PF01011.21 KFP03328.1 - 0.0049 16.7 4.4 1.4 8.9 0.0 4.5 4 0 0 4 4 4 1 PQQ enzyme repeat Nup160 PF11715.8 KFP03328.1 - 0.015 13.9 0.1 0.56 8.8 0.0 2.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFP03328.1 - 0.093 11.7 0.3 1.1 8.1 0.0 2.7 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein P34-Arc PF04045.14 KFP03329.1 - 2.5e-99 331.9 2.2 2.9e-99 331.6 2.2 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 KFP03329.1 - 0.026 14.2 0.1 0.067 12.8 0.1 1.7 2 0 0 2 2 2 0 ARP2/3 complex 20 kDa subunit (ARPC4) Calici_coat PF00915.20 KFP03329.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Calicivirus coat protein RUN PF02759.19 KFP03330.1 - 2.1e-12 47.2 0.5 2.3e-12 47.0 0.5 1.0 1 0 0 1 1 1 1 RUN domain PTB PF08416.13 KFP03331.1 - 4.8e-38 130.3 0.0 1e-37 129.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PTEN_C2 PF10409.9 KFP03331.1 - 2e-32 111.8 0.0 3.1e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein SH2 PF00017.24 KFP03331.1 - 9.6e-09 35.2 0.0 2e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 SH2 domain Thyroglobulin_1 PF00086.18 KFP03332.1 - 3.3e-19 68.3 3.3 6.2e-19 67.4 3.3 1.5 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat Thyroglobulin_1 PF00086.18 KFP03333.1 - 1.6e-16 59.7 0.8 3.5e-16 58.6 0.8 1.5 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat Cys_rich_CWC PF14375.6 KFP03333.1 - 0.036 14.5 0.6 0.085 13.3 0.6 1.7 1 0 0 1 1 1 0 Cysteine-rich CWC Ribosomal_L37ae PF01780.19 KFP03334.1 - 3.8e-47 158.3 11.2 4.2e-47 158.1 11.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 KFP03334.1 - 0.005 16.9 5.0 0.0071 16.4 4.2 1.6 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Elf1 PF05129.13 KFP03334.1 - 0.011 15.8 0.3 0.015 15.3 0.3 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Rsm1 PF08600.10 KFP03334.1 - 0.013 15.6 0.6 0.018 15.2 0.6 1.3 1 0 0 1 1 1 0 Rsm1-like Zn_Tnp_IS1595 PF12760.7 KFP03334.1 - 0.051 13.6 1.8 0.075 13.0 1.8 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C4_ClpX PF06689.13 KFP03334.1 - 0.13 12.2 4.0 0.4 10.6 4.0 1.9 1 1 0 1 1 1 0 ClpX C4-type zinc finger zf-BED PF02892.15 KFP03334.1 - 0.73 9.9 6.0 5.1 7.2 0.7 2.2 1 1 1 2 2 2 0 BED zinc finger HARP PF07443.13 KFP03335.1 - 4e-53 176.9 1.0 1.7e-25 88.4 0.1 2.4 2 0 0 2 2 2 2 HepA-related protein (HARP) SNF2_N PF00176.23 KFP03335.1 - 5.8e-25 87.7 0.0 9.6e-25 87.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFP03335.1 - 2.3e-14 53.6 0.1 8.1e-14 51.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KFP03335.1 - 1.8e-07 30.6 0.3 1e-05 24.9 0.1 2.3 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KFP03335.1 - 1.3e-06 28.6 0.0 5.6e-05 23.2 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit RVT_1 PF00078.27 KFP03336.1 - 0.025 14.1 0.0 0.16 11.4 0.0 2.1 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RINGv PF12906.7 KFP03337.1 - 5.3e-07 29.7 10.8 1.1e-06 28.6 10.8 1.6 1 0 0 1 1 1 1 RING-variant domain Ku_N PF03731.15 KFP03339.1 - 6e-59 199.4 0.5 6e-59 199.4 0.5 2.1 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.16 KFP03339.1 - 3.9e-48 163.9 1.2 6.9e-48 163.1 1.2 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 KFP03339.1 - 7.7e-30 103.5 5.0 2.7e-29 101.8 1.5 2.8 3 0 0 3 3 3 1 Ku C terminal domain like Ku_C PF03730.14 KFP03339.1 - 6e-21 74.9 2.4 2.1e-20 73.2 2.4 2.0 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm VWA PF00092.28 KFP03339.1 - 0.0019 18.5 0.1 0.0057 16.9 0.1 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain PDDEXK_7 PF04411.12 KFP03339.1 - 0.022 14.7 0.5 0.069 13.1 0.5 1.8 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Cnl2_NKP2 PF09447.10 KFP03339.1 - 0.91 9.7 3.1 3.8 7.7 0.2 3.2 3 0 0 3 3 3 0 Cnl2/NKP2 family protein TMEM169 PF15052.6 KFP03340.1 - 4.1e-63 211.3 8.9 5.4e-63 210.9 8.9 1.1 1 0 0 1 1 1 1 TMEM169 protein family adh_short_C2 PF13561.6 KFP03341.1 - 9.9e-51 172.5 0.2 1.1e-50 172.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFP03341.1 - 1.2e-42 145.6 0.4 1.5e-42 145.3 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFP03341.1 - 0.008 16.1 0.1 0.013 15.4 0.1 1.4 1 1 0 1 1 1 1 KR domain CABS1 PF15367.6 KFP03341.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 Sacchrp_dh_NADP PF03435.18 KFP03341.1 - 0.14 12.4 0.0 0.35 11.1 0.0 1.6 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KFP03341.1 - 0.15 12.7 0.0 0.42 11.2 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pkinase PF00069.25 KFP03342.1 - 7.5e-66 222.2 0.0 9.7e-66 221.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP03342.1 - 4.3e-39 134.4 0.0 5.8e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.24 KFP03342.1 - 9.5e-13 47.9 0.2 2e-12 46.8 0.2 1.6 1 0 0 1 1 1 1 PB1 domain Kinase-like PF14531.6 KFP03342.1 - 5.7e-06 25.9 0.0 0.0014 18.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like FTA2 PF13095.6 KFP03342.1 - 0.03 14.0 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KFP03342.1 - 0.041 13.2 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ERCC3_RAD25_C PF16203.5 KFP03343.1 - 6.8e-125 415.2 2.0 1.1e-124 414.5 2.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KFP03343.1 - 1.6e-38 131.7 0.0 4.9e-38 130.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP03343.1 - 4.5e-16 59.3 0.0 1.4e-15 57.7 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFP03343.1 - 1.9e-09 37.9 0.1 4.7e-09 36.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KFP03343.1 - 0.0012 17.6 0.1 0.0023 16.7 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain p450 PF00067.22 KFP03344.1 - 1.3e-102 344.0 0.0 1.4e-102 343.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Importin_rep_6 PF18829.1 KFP03344.1 - 0.02 15.0 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 Importin repeat 6 BAR PF03114.18 KFP03345.1 - 3.4e-43 148.0 9.1 4.5e-43 147.6 9.1 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 KFP03345.1 - 7.2e-12 45.0 0.2 3.3e-11 42.9 0.2 2.0 1 1 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP03345.1 - 4e-07 29.5 0.1 9.7e-07 28.3 0.1 1.7 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP03345.1 - 4.6e-06 26.2 0.0 1.1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 KFP03345.1 - 0.0017 18.1 8.2 0.0044 16.8 7.9 1.8 1 1 0 1 1 1 1 BAR domain of APPL family Jnk-SapK_ap_N PF09744.9 KFP03345.1 - 0.019 15.2 1.1 0.019 15.2 1.1 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 OmpH PF03938.14 KFP03345.1 - 0.024 15.0 6.3 0.04 14.2 0.3 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF3104 PF11302.8 KFP03345.1 - 0.08 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) BLOC1_2 PF10046.9 KFP03345.1 - 0.88 9.9 9.1 0.37 11.1 1.8 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PTS_IIA PF02255.16 KFP03345.1 - 1.4 9.0 6.0 6.4 6.9 1.4 2.8 2 1 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit Arfaptin PF06456.13 KFP03345.1 - 1.8 8.1 7.6 4.6 6.8 7.6 1.7 1 1 0 1 1 1 0 Arfaptin-like domain RVT_1 PF00078.27 KFP03346.1 - 0.029 13.9 0.0 0.078 12.5 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Syndecan PF01034.20 KFP03347.1 - 0.00052 19.9 0.1 0.00076 19.4 0.1 1.3 1 0 0 1 1 1 1 Syndecan domain Protocadherin PF08374.11 KFP03347.1 - 0.0037 17.3 0.0 0.0039 17.2 0.0 1.1 1 0 0 1 1 1 1 Protocadherin Spore_SspJ PF09575.10 KFP03347.1 - 0.015 15.7 0.8 0.021 15.2 0.8 1.2 1 0 0 1 1 1 0 Small spore protein J (Spore_SspJ) FAM163 PF15069.6 KFP03347.1 - 0.022 15.2 0.0 0.024 15.1 0.0 1.1 1 0 0 1 1 1 0 FAM163 family EphA2_TM PF14575.6 KFP03347.1 - 0.024 15.5 0.0 0.028 15.3 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MAP17 PF15807.5 KFP03347.1 - 0.024 14.8 0.0 0.03 14.6 0.0 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 FTCD_C PF04961.12 KFP03347.1 - 0.04 13.7 0.0 0.043 13.6 0.0 1.0 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Chordopox_A13L PF05961.11 KFP03347.1 - 0.058 13.6 0.0 0.07 13.4 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Baculo_11_kDa PF06143.11 KFP03347.1 - 0.078 12.6 0.0 0.098 12.2 0.0 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF202 PF02656.15 KFP03347.1 - 0.11 12.9 0.3 0.14 12.6 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF202) DUF4692 PF15763.5 KFP03347.1 - 0.12 12.8 0.0 0.14 12.6 0.0 1.1 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) ODV-E18 PF10717.9 KFP03347.1 - 0.13 12.1 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Adeno_E3_CR2 PF02439.15 KFP03347.1 - 0.51 10.1 6.4 0.82 9.5 6.4 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Laminin_G_2 PF02210.24 KFP03348.1 - 4.9e-62 208.1 1.1 2.3e-22 79.9 0.0 3.3 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.23 KFP03348.1 - 2.5e-47 160.4 0.1 9.1e-19 68.0 0.0 3.4 3 0 0 3 3 3 3 Laminin G domain Laminin_G_3 PF13385.6 KFP03348.1 - 8.3e-10 39.0 0.0 0.00033 20.8 0.0 3.3 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 KFP03348.1 - 8e-08 32.5 33.7 7.6e-05 22.9 5.7 3.9 3 1 1 4 4 4 2 EGF-like domain EGF_2 PF07974.13 KFP03348.1 - 0.0069 16.7 13.2 0.0069 16.7 13.2 3.8 4 0 0 4 4 4 2 EGF-like domain PMP1_2 PF08114.11 KFP03348.1 - 0.071 12.9 0.2 0.13 12.0 0.2 1.4 1 0 0 1 1 1 0 ATPase proteolipid family Protocadherin PF08374.11 KFP03348.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Protocadherin hEGF PF12661.7 KFP03348.1 - 1.8 9.3 32.1 0.035 14.7 8.1 4.2 4 0 0 4 4 4 0 Human growth factor-like EGF F5_F8_type_C PF00754.25 KFP03349.1 - 2.6e-16 59.9 1.6 2.8e-16 59.8 1.6 1.0 1 0 0 1 1 1 1 F5/8 type C domain Ras PF00071.22 KFP03350.1 - 2.6e-53 180.0 0.0 2.9e-53 179.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP03350.1 - 2.3e-20 73.0 0.0 3e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KFP03350.1 - 4.3e-07 29.7 0.1 1.2e-06 28.2 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KFP03350.1 - 1.4e-06 27.9 0.0 1.7e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFP03350.1 - 2.4e-05 24.3 0.6 0.025 14.5 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFP03350.1 - 0.0018 18.3 0.0 0.0027 17.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KFP03350.1 - 0.014 15.2 0.7 0.059 13.1 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KFP03350.1 - 0.069 13.5 0.1 0.12 12.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1_Xtn PF16897.5 KFP03350.1 - 0.085 12.9 0.0 0.16 12.0 0.0 1.4 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Gtr1_RagA PF04670.12 KFP03350.1 - 0.097 12.0 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FERM_C PF09380.10 KFP03352.1 - 1e-21 77.1 0.0 1.8e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FA PF08736.11 KFP03352.1 - 2.6e-14 53.0 12.0 5.8e-14 51.9 12.0 1.6 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_M PF00373.18 KFP03352.1 - 3.4e-14 53.3 1.0 1.7e-13 51.0 0.4 2.4 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.10 KFP03352.1 - 6.7e-14 51.6 0.2 2.4e-13 49.8 0.1 1.9 2 0 0 2 2 2 1 FERM N-terminal domain Ras PF00071.22 KFP03353.1 - 7.6e-55 184.9 0.1 8.7e-55 184.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP03353.1 - 3.8e-21 75.5 0.0 6e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP03353.1 - 4.3e-10 39.3 0.0 5e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFP03353.1 - 1.3e-09 38.1 0.1 1.4e-05 25.1 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KFP03353.1 - 2e-05 24.1 0.0 2.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KFP03353.1 - 6.7e-05 22.5 0.0 0.00026 20.6 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFP03353.1 - 0.00051 20.1 0.0 0.00084 19.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFP03353.1 - 0.00079 18.8 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_25 PF13481.6 KFP03353.1 - 0.0029 17.2 0.0 0.0054 16.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain Septin PF00735.18 KFP03353.1 - 0.0075 15.6 0.0 1 8.6 0.0 2.1 2 0 0 2 2 2 2 Septin FeoB_N PF02421.18 KFP03353.1 - 0.029 13.9 0.0 0.36 10.3 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B Ser_hydrolase PF06821.13 KFP03353.1 - 0.17 11.7 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase zf-C2H2 PF00096.26 KFP03354.1 - 4e-18 64.8 37.2 0.00034 20.9 0.5 6.4 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP03354.1 - 4.2e-12 45.9 30.6 1.7e-06 28.2 1.4 5.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP03354.1 - 1.1e-05 25.9 32.1 0.0052 17.5 0.3 6.2 6 0 0 6 6 6 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFP03354.1 - 2.1e-05 25.1 26.8 0.026 15.1 0.1 5.8 2 1 2 5 5 5 2 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 KFP03354.1 - 0.17 12.0 16.8 1.6 8.8 3.4 3.6 2 1 1 3 3 3 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 KFP03354.1 - 5.4 7.1 5.4 2.8 8.0 2.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger PcF PF09461.10 KFP03354.1 - 9.3 6.7 7.8 44 4.6 0.3 4.1 3 1 1 4 4 4 0 Phytotoxin PcF protein CP2 PF04516.15 KFP03355.1 - 7.6e-57 192.2 0.0 1.1e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 CP2 transcription factor SAM_3 PF18016.1 KFP03355.1 - 2.4e-17 62.5 0.0 4.4e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFP03355.1 - 0.022 14.7 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain CLASP_N PF12348.8 KFP03356.1 - 4.4e-55 186.7 14.4 2.2e-36 125.6 0.5 4.9 4 1 0 4 4 4 3 CLASP N terminal HEAT PF02985.22 KFP03356.1 - 5e-19 66.8 8.6 1.2e-05 25.1 0.0 9.7 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.6 KFP03356.1 - 7.7e-12 45.5 2.1 0.016 15.7 0.1 5.9 6 0 0 6 6 4 3 HEAT-like repeat HEAT_2 PF13646.6 KFP03356.1 - 1.3e-10 41.5 4.1 0.1 13.0 0.0 7.8 5 2 4 10 10 10 4 HEAT repeats Cnd1 PF12717.7 KFP03356.1 - 4.9e-08 33.2 8.6 0.0046 17.0 0.9 6.2 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Sec7_N PF12783.7 KFP03356.1 - 1.2e-07 31.8 6.8 0.017 15.0 0.0 5.3 5 0 0 5 5 5 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Vac14_Fab1_bd PF12755.7 KFP03356.1 - 2.4e-07 31.3 1.7 1.9 9.2 0.0 6.0 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 KFP03356.1 - 5.7e-06 26.5 9.8 0.061 13.5 0.1 5.6 6 2 1 7 7 6 2 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KFP03356.1 - 1.1e-05 24.2 8.5 1.2 7.6 0.0 5.9 5 2 0 7 7 7 3 Adaptin N terminal region Tti2 PF10521.9 KFP03356.1 - 0.00013 21.6 4.6 2.4 7.6 0.0 5.3 4 1 0 5 5 5 2 Tti2 family ParcG PF10274.9 KFP03356.1 - 0.00022 21.4 0.5 0.0075 16.4 0.1 3.1 1 1 1 2 2 2 1 Parkin co-regulated protein TFCD_C PF12612.8 KFP03356.1 - 0.00086 19.2 1.1 0.026 14.4 0.2 3.6 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal MMS19_C PF12460.8 KFP03356.1 - 0.0024 17.1 1.4 1.6 7.8 0.1 3.3 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 KFP03356.1 - 0.0029 17.2 6.0 0.61 9.6 0.2 4.6 3 2 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II Dopey_N PF04118.14 KFP03356.1 - 0.0079 15.4 4.1 0.36 9.9 0.1 3.5 4 0 0 4 4 4 1 Dopey, N-terminal TAN PF11640.8 KFP03356.1 - 0.015 15.4 2.4 0.22 11.7 0.1 3.9 4 0 0 4 4 4 0 Telomere-length maintenance and DNA damage repair XRN_M PF17846.1 KFP03356.1 - 0.02 13.9 0.0 0.039 12.9 0.0 1.4 1 0 0 1 1 1 0 Xrn1 helical domain HMW1C_N PF18071.1 KFP03356.1 - 0.068 13.0 0.0 2.2 8.1 0.0 2.5 2 0 0 2 2 2 0 HMW1C N-terminal RasGEF_N_2 PF14663.6 KFP03356.1 - 0.082 13.3 0.2 8.2 6.9 0.1 3.8 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain TPR_20 PF14561.6 KFP03356.1 - 0.1 13.0 3.1 0.35 11.2 0.4 3.3 2 1 1 3 3 2 0 Tetratricopeptide repeat hNIFK_binding PF12196.8 KFP03357.1 - 1.4e-18 66.1 2.8 2.4e-18 65.3 2.8 1.4 1 0 0 1 1 1 1 FHA Ki67 binding domain of hNIFK RRM_1 PF00076.22 KFP03357.1 - 1.3e-06 28.1 0.0 2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Translin PF01997.16 KFP03358.1 - 1.4e-45 155.8 0.1 1.5e-45 155.7 0.1 1.0 1 0 0 1 1 1 1 Translin family RhoGEF PF00621.20 KFP03359.1 - 1.4e-37 129.7 2.6 2.9e-37 128.7 2.6 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 KFP03359.1 - 0.033 14.0 0.0 0.079 12.8 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Sda PF08970.10 KFP03359.1 - 0.034 13.9 1.0 0.081 12.7 1.0 1.7 1 0 0 1 1 1 0 Sporulation inhibitor A IDEAL PF08858.10 KFP03359.1 - 0.13 12.0 1.6 0.38 10.5 1.6 1.8 1 0 0 1 1 1 0 IDEAL domain MKRN1_C PF15815.5 KFP03359.1 - 0.18 12.2 2.1 1.8 9.0 0.2 2.7 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase makorin-1, C-terminal IQ PF00612.27 KFP03361.1 - 1.6e-12 46.0 19.4 3.9e-06 26.2 0.7 5.2 4 0 0 4 4 4 2 IQ calmodulin-binding motif Caudo_TAP PF02413.17 KFP03361.1 - 0.015 15.5 0.7 0.015 15.5 0.7 2.1 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK Pneumo_NS1 PF03438.13 KFP03361.1 - 0.065 13.4 0.3 0.31 11.2 0.2 2.1 2 0 0 2 2 2 0 Pneumovirus NS1 protein Ndr PF03096.14 KFP03361.1 - 0.47 9.1 2.2 1.5 7.5 0.2 2.1 2 0 0 2 2 2 0 Ndr family EAF PF09816.9 KFP03362.1 - 2.5e-14 53.5 0.2 7.6e-14 51.9 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor AF-4 PF05110.13 KFP03362.1 - 0.0043 15.2 24.5 0.0055 14.9 24.5 1.3 1 0 0 1 1 1 1 AF-4 proto-oncoprotein PAN_3 PF08277.12 KFP03362.1 - 0.049 13.4 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 PAN-like domain BBP1_C PF15272.6 KFP03362.1 - 0.31 10.8 6.4 0.47 10.3 6.4 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Macoilin PF09726.9 KFP03362.1 - 0.32 9.5 11.2 0.35 9.4 11.2 1.1 1 0 0 1 1 1 0 Macoilin family Cwf_Cwc_15 PF04889.12 KFP03362.1 - 0.77 9.4 10.9 1.3 8.8 10.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.9 KFP03362.1 - 0.85 9.2 23.3 1.5 8.4 23.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Lin-8 PF03353.15 KFP03362.1 - 1.1 8.8 9.4 1.3 8.5 9.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PTR2 PF00854.21 KFP03363.1 - 2.2e-48 165.1 4.6 3e-48 164.6 4.6 1.2 1 0 0 1 1 1 1 POT family Cupin_8 PF13621.6 KFP03364.1 - 2.6e-36 125.7 0.0 3.7e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KFP03364.1 - 2.8e-09 36.9 0.0 4.6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 KFP03364.1 - 0.00073 19.9 0.1 0.0015 19.0 0.1 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Pox_C7_F8A PF03287.14 KFP03364.1 - 0.078 13.0 0.0 4.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Poxvirus C7/F8A protein MFS_1 PF07690.16 KFP03365.1 - 8.9e-06 24.9 27.4 8.9e-06 24.9 27.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sema PF01403.19 KFP03366.1 - 1.2e-132 442.8 0.7 2.3e-132 441.8 0.1 1.8 2 0 0 2 2 2 1 Sema domain TSP_1 PF00090.19 KFP03366.1 - 2.2e-43 146.2 96.4 1.4e-10 41.2 9.0 7.7 7 0 0 7 7 7 5 Thrombospondin type 1 domain 7TM_GPCR_Srz PF10325.9 KFP03366.1 - 0.076 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz Thioredoxin PF00085.20 KFP03367.1 - 2e-71 236.5 3.3 2.4e-24 85.3 0.0 4.2 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_2 PF13098.6 KFP03367.1 - 2.6e-27 95.4 4.3 3.9e-08 33.7 0.3 4.2 4 1 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFP03367.1 - 1.2e-17 63.8 0.1 1.5e-05 25.1 0.0 3.6 3 0 0 3 3 3 3 Thioredoxin-like AhpC-TSA PF00578.21 KFP03367.1 - 6.5e-17 61.6 0.6 1.9e-05 24.5 0.1 3.6 3 0 0 3 3 3 3 AhpC/TSA family Thioredoxin_8 PF13905.6 KFP03367.1 - 1.9e-14 53.8 0.5 0.00057 20.2 0.1 5.1 3 2 2 5 5 5 3 Thioredoxin-like OST3_OST6 PF04756.13 KFP03367.1 - 3.1e-13 49.7 0.0 9.3e-05 21.9 0.0 3.1 2 1 1 3 3 3 3 OST3 / OST6 family, transporter family Thioredoxin_6 PF13848.6 KFP03367.1 - 4.2e-12 46.3 0.3 0.01 15.8 0.0 4.2 5 0 0 5 5 5 3 Thioredoxin-like domain Redoxin PF08534.10 KFP03367.1 - 5.3e-12 45.7 1.3 0.011 15.5 0.0 3.4 2 1 1 3 3 3 3 Redoxin TraF PF13728.6 KFP03367.1 - 1.5e-08 34.8 0.0 0.14 11.9 0.0 3.6 3 0 0 3 3 3 3 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 KFP03367.1 - 2e-08 34.1 0.0 0.035 13.9 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin HyaE PF07449.11 KFP03367.1 - 3.4e-05 23.8 0.0 1.4 8.9 0.0 3.7 3 1 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 KFP03367.1 - 0.00011 22.2 0.3 0.29 11.2 0.0 3.5 3 0 0 3 3 3 1 Thioredoxin domain Glutaredoxin PF00462.24 KFP03367.1 - 0.017 15.4 13.6 0.61 10.3 0.2 4.8 4 2 0 4 4 4 0 Glutaredoxin Thioredoxin_4 PF13462.6 KFP03367.1 - 0.19 11.9 7.7 7 6.8 0.8 3.6 2 1 0 3 3 3 0 Thioredoxin DSBA PF01323.20 KFP03367.1 - 0.42 10.4 5.2 20 4.9 0.2 4.6 3 3 3 6 6 6 0 DSBA-like thioredoxin domain Longin PF13774.6 KFP03368.1 - 6.6e-20 71.0 0.2 1.3e-19 70.0 0.2 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Guanylate_cyc PF00211.20 KFP03369.1 - 3.4e-122 404.9 3.0 1.2e-62 210.8 0.5 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 KFP03369.1 - 9.6e-57 193.0 3.8 9.6e-57 193.0 3.8 2.3 2 0 0 2 2 2 1 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF1053 PF06327.14 KFP03369.1 - 1.7e-25 89.5 0.4 4.9e-25 88.1 0.4 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) HNOBA PF07701.14 KFP03369.1 - 0.0014 18.1 1.2 0.4 10.1 0.1 2.5 2 0 0 2 2 2 2 Heme NO binding associated TBK1_ULD PF18396.1 KFP03369.1 - 0.021 14.8 0.1 0.049 13.6 0.1 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain PTPLA PF04387.14 KFP03370.1 - 2.7e-42 144.3 10.0 3e-42 144.2 10.0 1.0 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA I-set PF07679.16 KFP03371.1 - 1.3e-212 688.6 11.0 1.3e-28 98.8 0.1 10.1 10 0 0 10 10 10 9 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP03371.1 - 4.6e-134 437.3 9.1 3.5e-15 56.3 0.0 10.4 10 0 0 10 10 10 9 Immunoglobulin domain ig PF00047.25 KFP03371.1 - 1.8e-92 303.6 12.6 8e-12 45.2 0.0 9.6 9 0 0 9 9 9 9 Immunoglobulin domain Ig_2 PF13895.6 KFP03371.1 - 2.2e-84 277.9 11.0 1.2e-10 41.5 0.0 9.9 10 0 0 10 10 10 9 Immunoglobulin domain Pkinase PF00069.25 KFP03371.1 - 7.8e-77 258.2 0.0 1.5e-76 257.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain 23ISL PF16620.5 KFP03371.1 - 3.1e-43 147.8 15.4 3.1e-43 147.8 15.4 3.1 3 0 0 3 3 1 1 Unstructured linker between I-set domains 2 and 3 on MYLCK V-set PF07686.17 KFP03371.1 - 2.6e-42 143.4 22.3 0.00013 22.1 0.3 16.0 10 7 1 11 11 10 9 Immunoglobulin V-set domain Pkinase_Tyr PF07714.17 KFP03371.1 - 1.1e-35 123.2 0.0 2.1e-35 122.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase C2-set_2 PF08205.12 KFP03371.1 - 1.3e-24 86.1 4.2 0.014 15.5 0.0 9.2 8 0 0 8 8 8 6 CD80-like C2-set immunoglobulin domain fn3 PF00041.21 KFP03371.1 - 4.3e-17 62.2 2.1 8.7e-17 61.3 0.2 2.6 2 0 0 2 2 2 1 Fibronectin type III domain Ig_6 PF18452.1 KFP03371.1 - 3.4e-11 42.5 0.5 0.41 10.3 0.0 7.3 8 0 0 8 8 7 3 Immunoglobulin domain Receptor_2B4 PF11465.8 KFP03371.1 - 5.2e-11 42.7 2.7 0.091 13.0 0.0 8.2 9 0 0 9 9 9 2 Natural killer cell receptor 2B4 Ig_C17orf99 PF17736.1 KFP03371.1 - 1.2e-10 41.2 0.4 0.19 11.8 0.1 7.7 10 0 0 10 10 8 2 C17orf99 Ig domain Izumo-Ig PF16706.5 KFP03371.1 - 5.7e-09 35.9 10.5 0.042 13.9 0.0 8.4 9 0 0 9 9 9 2 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 KFP03371.1 - 9.6e-09 35.4 14.4 1.4 9.2 0.0 8.9 9 0 0 9 9 8 3 T-cell surface glycoprotein CD3 delta chain BiPBP_C PF06832.12 KFP03371.1 - 1.4e-08 34.6 0.1 13 5.9 0.0 7.3 7 0 0 7 7 7 0 Penicillin-Binding Protein C-terminus Family Herpes_gE PF02480.16 KFP03371.1 - 1.2e-07 30.8 0.2 0.0034 16.2 0.0 5.1 7 0 0 7 7 7 1 Alphaherpesvirus glycoprotein E Kinase-like PF14531.6 KFP03371.1 - 0.0012 18.2 0.0 0.0048 16.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFP03371.1 - 0.028 13.8 0.1 0.066 12.6 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family V-set_CD47 PF08204.11 KFP03371.1 - 0.035 14.1 7.2 17 5.4 0.0 5.9 7 0 0 7 7 7 0 CD47 immunoglobulin-like domain Pur_ac_phosph_N PF16656.5 KFP03371.1 - 0.037 14.6 0.2 0.23 12.0 0.2 2.5 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain RIO1 PF01163.22 KFP03371.1 - 0.049 13.2 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Kelch_1 PF01344.25 KFP03371.1 - 1.9 8.2 4.4 0.42 10.2 0.3 2.0 2 0 0 2 2 2 0 Kelch motif CCDC14 PF15254.6 KFP03373.1 - 0 1123.1 34.8 0 1122.9 34.8 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 14 GM_CSF PF01109.17 KFP03373.1 - 0.083 13.0 0.6 0.66 10.1 0.1 2.4 2 0 0 2 2 2 0 Granulocyte-macrophage colony-stimulating factor Mto2_bdg PF12808.7 KFP03373.1 - 5.2 7.5 13.3 0.64 10.4 1.3 4.2 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Spectrin PF00435.21 KFP03374.1 - 1e-44 151.3 82.6 1.5e-10 41.5 2.2 9.6 7 2 1 8 8 8 6 Spectrin repeat RhoGEF PF00621.20 KFP03374.1 - 2.3e-36 125.8 0.5 2.3e-36 125.8 0.5 4.9 3 1 2 5 5 4 1 RhoGEF domain SH3_1 PF00018.28 KFP03374.1 - 1.9e-07 30.6 0.0 6.3e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFP03374.1 - 3.7e-07 29.9 0.2 1.4e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain PH PF00169.29 KFP03374.1 - 8.7e-07 29.4 0.9 4.1e-06 27.2 0.2 2.6 2 0 0 2 2 2 1 PH domain CRAL_TRIO_2 PF13716.6 KFP03374.1 - 1.3e-05 25.4 0.0 0.00049 20.3 0.0 3.2 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain SH3_2 PF07653.17 KFP03374.1 - 0.00073 19.2 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_10 PF15411.6 KFP03374.1 - 0.0024 18.1 0.2 0.016 15.4 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain SH3-RhoG_link PF16609.5 KFP03374.1 - 0.0052 16.6 0.3 0.011 15.5 0.3 1.6 1 0 0 1 1 1 1 SH3-RhoGEF linking unstructured region T4_Rnl2_C PF18043.1 KFP03374.1 - 0.01 15.9 2.0 0.018 15.2 0.1 2.5 2 0 0 2 2 2 0 T4 RNA ligase 2 C-terminal Exonuc_VII_S PF02609.16 KFP03374.1 - 2.8 8.1 6.3 3.8 7.6 0.2 3.8 3 0 0 3 3 3 0 Exonuclease VII small subunit Nod1 PF17114.5 KFP03374.1 - 6.9 6.8 10.2 3.3 7.8 0.9 4.3 3 1 1 4 4 4 0 Gef2-related medial cortical node protein Nod1 Pkinase PF00069.25 KFP03375.1 - 1.1e-18 67.6 0.0 1.2e-18 67.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP03375.1 - 3.4e-06 26.6 0.0 4.4e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase T2SSK PF03934.13 KFP03375.1 - 0.092 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K OMPdecase PF00215.24 KFP03376.1 - 5.3e-76 255.1 0.0 8.9e-76 254.4 0.0 1.4 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 KFP03376.1 - 6.5e-13 48.5 0.0 1.8e-12 47.0 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Integrin_beta PF00362.18 KFP03377.1 - 8.5e-110 366.2 0.0 1.2e-109 365.8 0.0 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_B_tail PF07965.12 KFP03377.1 - 1.4e-17 64.0 4.8 1.4e-17 64.0 4.8 4.4 3 1 1 4 4 4 1 Integrin beta tail domain Integrin_b_cyt PF08725.11 KFP03377.1 - 5.6e-17 61.1 0.2 5.6e-17 61.1 0.2 1.9 2 0 0 2 2 2 1 Integrin beta cytoplasmic domain PSI_integrin PF17205.3 KFP03377.1 - 5.6e-13 48.4 8.9 5.6e-13 48.4 8.9 4.5 4 0 0 4 4 4 1 Integrin plexin domain EGF_2 PF07974.13 KFP03377.1 - 6e-08 32.9 73.6 0.00022 21.5 15.9 4.5 4 0 0 4 4 4 3 EGF-like domain I-EGF_1 PF18372.1 KFP03377.1 - 0.0047 17.0 12.1 0.0047 17.0 12.1 4.4 4 0 0 4 4 4 2 Integrin beta epidermal growth factor like domain 1 DUF2975 PF11188.8 KFP03377.1 - 0.091 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) EGF_CA PF07645.15 KFP03379.1 - 9.4e-07 28.9 5.7 9.4e-07 28.9 5.7 4.7 2 2 3 5 5 5 2 Calcium-binding EGF domain EGF_MSP1_1 PF12946.7 KFP03379.1 - 0.0002 21.4 7.1 0.0002 21.4 7.1 3.8 3 1 1 4 4 4 1 MSP1 EGF domain 1 hEGF PF12661.7 KFP03379.1 - 0.00021 21.8 11.5 0.0044 17.6 2.0 4.1 3 0 0 3 3 3 2 Human growth factor-like EGF EGF_3 PF12947.7 KFP03379.1 - 0.00025 21.2 23.4 0.0091 16.2 6.7 3.4 2 1 1 3 3 3 2 EGF domain EGF PF00008.27 KFP03379.1 - 0.00035 20.8 5.5 0.00035 20.8 5.5 4.1 4 1 0 4 4 4 2 EGF-like domain Orthoreo_P10 PF07204.11 KFP03379.1 - 0.013 15.4 0.2 0.03 14.3 0.2 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 FXa_inhibition PF14670.6 KFP03379.1 - 0.31 11.3 31.9 0.24 11.7 10.5 4.3 2 1 1 3 3 3 0 Coagulation Factor Xa inhibitory site EB PF01683.18 KFP03379.1 - 1 9.7 33.0 0.19 12.1 7.6 3.8 3 1 1 4 4 4 0 EB module cEGF PF12662.7 KFP03379.1 - 3.5 7.6 24.1 0.69 9.9 2.4 4.6 4 0 0 4 4 4 0 Complement Clr-like EGF-like AA_permease PF00324.21 KFP03380.1 - 9.4e-44 149.8 37.4 9.4e-44 149.8 37.4 2.0 2 0 0 2 2 2 2 Amino acid permease HR1 PF02185.16 KFP03380.1 - 0.19 11.9 1.0 0.4 10.8 1.0 1.4 1 0 0 1 1 1 0 Hr1 repeat zf-H2C2_2 PF13465.6 KFP03381.1 - 1.7e-22 78.8 22.4 4.2e-07 30.1 0.3 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFP03381.1 - 2.7e-12 46.4 37.8 0.00032 21.0 4.0 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP03381.1 - 9.4e-10 38.5 33.8 0.025 15.4 1.0 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger RBFA PF02033.18 KFP03381.1 - 0.042 14.3 0.2 0.11 13.0 0.2 1.7 1 0 0 1 1 1 0 Ribosome-binding factor A zf-C2H2_jaz PF12171.8 KFP03381.1 - 0.38 11.1 15.3 3.1 8.2 2.2 3.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DNA_RNApol_7kD PF03604.13 KFP03381.1 - 0.39 10.4 1.7 1.2 8.8 0.3 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.7 KFP03381.1 - 0.8 9.8 7.6 7.4 6.7 1.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 KFP03381.1 - 4.1 8.2 9.4 20 6.0 1.5 2.7 1 1 1 2 2 2 0 zinc-ribbon family zf-MYST PF17772.1 KFP03381.1 - 8.1 6.1 16.5 0.049 13.2 3.3 2.9 2 1 1 3 3 3 0 MYST family zinc finger domain PX PF00787.24 KFP03382.1 - 4.9e-23 81.3 0.0 1.2e-22 80.1 0.0 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KFP03382.1 - 1.3e-05 24.9 10.8 0.0028 17.2 10.8 2.2 1 1 0 1 1 1 1 Vps5 C terminal like FlgM PF04316.13 KFP03382.1 - 0.042 14.2 0.2 0.13 12.7 0.2 1.9 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM Indigoidine_A PF04227.12 KFP03382.1 - 0.19 11.0 0.1 0.31 10.3 0.1 1.2 1 0 0 1 1 1 0 Indigoidine synthase A like protein V-SNARE PF05008.15 KFP03382.1 - 2.1 8.8 7.4 0.95 9.9 0.7 3.1 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Tnp_22_trimer PF17489.2 KFP03382.1 - 3 7.9 6.1 2.7 8.0 0.8 2.5 2 0 0 2 2 2 0 L1 transposable element trimerization domain Med9 PF07544.13 KFP03382.1 - 3.3 7.9 6.0 16 5.7 5.8 2.3 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 ecTbetaR2 PF08917.10 KFP03383.1 - 4.9e-43 145.6 12.8 1.2e-42 144.3 12.8 1.7 1 0 0 1 1 1 1 Transforming growth factor beta receptor 2 ectodomain Pkinase PF00069.25 KFP03383.1 - 2e-30 106.0 0.0 3.5e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP03383.1 - 1.2e-28 100.1 0.0 3.4e-28 98.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP03383.1 - 3.9e-05 22.6 0.0 6.3e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase SIT PF15330.6 KFP03383.1 - 0.063 13.7 0.1 1 9.8 0.1 2.5 3 0 0 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT Oxysterol_BP PF01237.18 KFP03384.1 - 9.6e-83 278.1 3.3 6.1e-81 272.1 3.3 2.2 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 KFP03384.1 - 6.2e-12 46.0 0.0 1.3e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFP03384.1 - 1.6e-08 34.7 0.0 3.8e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 KFP03384.1 - 3.1e-05 24.2 0.0 7.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 KFP03384.1 - 0.003 17.9 0.1 0.0083 16.5 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 KFP03384.1 - 0.042 13.6 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain NAD_Gly3P_dh_C PF07479.14 KFP03385.1 - 1.2e-51 174.7 0.8 4e-51 173.0 0.3 2.1 3 0 0 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KFP03385.1 - 1.9e-45 154.7 0.1 3.8e-45 153.7 0.0 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GerD PF17898.1 KFP03385.1 - 0.03 14.2 0.2 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 Spore germination GerD central core domain Peptidase_M8 PF01457.16 KFP03386.1 - 8.5e-49 166.6 10.0 1e-19 70.7 0.0 4.0 3 1 1 4 4 4 4 Leishmanolysin WWE PF02825.20 KFP03387.1 - 4.4e-06 27.2 0.1 2.2e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 WWE domain DUF4318 PF14201.6 KFP03387.1 - 0.058 13.9 0.0 0.78 10.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4318) LSM PF01423.22 KFP03387.1 - 0.1 12.3 0.4 0.29 10.9 0.0 1.9 2 0 0 2 2 2 0 LSM domain RRM_occluded PF16842.5 KFP03388.1 - 3.2e-05 23.7 0.0 8.2e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 Occluded RNA-recognition motif ING PF12998.7 KFP03388.1 - 0.022 15.3 0.9 0.058 14.0 0.8 1.6 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding GBR_NSP5 PF17580.2 KFP03388.1 - 0.028 14.2 0.1 0.034 14.0 0.1 1.1 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 RRM_occluded PF16842.5 KFP03389.1 - 0.0014 18.4 0.1 0.32 10.9 0.1 2.4 1 1 1 2 2 2 2 Occluded RNA-recognition motif Collagen_bind PF05737.12 KFP03389.1 - 0.02 15.1 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 Collagen binding domain PA-IL PF07828.12 KFP03389.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 PA-IL-like protein DTC PF18102.1 KFP03390.1 - 3.3e-63 211.7 0.0 6.7e-63 210.7 0.0 1.6 1 0 0 1 1 1 1 Deltex C-terminal domain zf-C3HC4_2 PF13923.6 KFP03390.1 - 4.1e-11 42.5 13.3 8.2e-11 41.6 13.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP03390.1 - 9.8e-09 35.4 11.4 2.2e-08 34.3 11.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFP03390.1 - 2.4e-07 30.5 14.4 5.2e-07 29.4 14.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP03390.1 - 3.7e-06 26.7 9.0 7.7e-06 25.7 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP03390.1 - 3.3e-05 23.8 4.2 3.3e-05 23.8 4.2 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 KFP03390.1 - 0.00011 22.4 8.3 0.00035 20.8 8.3 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain Endonuclease_7 PF02945.15 KFP03390.1 - 0.0029 17.5 3.3 0.0073 16.2 3.3 1.6 1 0 0 1 1 1 1 Recombination endonuclease VII zf-RING_5 PF14634.6 KFP03390.1 - 0.003 17.5 12.8 0.0064 16.4 12.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain KH_1 PF00013.29 KFP03390.1 - 0.0055 16.5 0.0 0.16 11.8 0.0 2.6 2 0 0 2 2 2 1 KH domain zf-Nse PF11789.8 KFP03390.1 - 0.011 15.6 9.0 0.029 14.2 9.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 KFP03390.1 - 0.018 14.9 2.5 0.037 13.9 2.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Siva PF05458.12 KFP03390.1 - 0.032 13.9 1.6 0.06 13.0 1.6 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-RING_4 PF14570.6 KFP03390.1 - 0.054 13.3 9.4 0.16 11.8 9.4 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KFP03390.1 - 0.065 13.0 5.6 0.19 11.5 5.6 1.9 1 0 0 1 1 1 0 RING-like zinc finger Prok-RING_4 PF14447.6 KFP03390.1 - 0.079 12.8 11.5 5.1 7.0 12.1 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFP03390.1 - 0.086 13.0 9.2 0.22 11.7 9.2 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KFP03390.1 - 0.19 11.9 9.9 0.095 12.9 7.2 1.9 2 0 0 2 2 1 0 zinc RING finger of MSL2 DZR PF12773.7 KFP03390.1 - 0.33 11.0 9.3 0.89 9.6 9.3 1.7 1 0 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 KFP03390.1 - 0.71 9.9 6.5 1.8 8.6 6.5 1.7 1 0 0 1 1 1 0 zinc-ribbons Macro PF01661.21 KFP03391.1 - 5e-43 145.9 0.5 1.2e-32 112.4 0.8 2.5 2 0 0 2 2 2 2 Macro domain PARP PF00644.20 KFP03391.1 - 8.6e-06 25.5 0.6 6.2e-05 22.7 0.6 2.3 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain FAIM1 PF06905.13 KFP03392.1 - 1.4e-85 285.3 2.8 1.6e-85 285.2 2.8 1.0 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) DUF3748 PF12566.8 KFP03392.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) CBM-like PF14683.6 KFP03392.1 - 0.092 12.6 0.1 0.18 11.7 0.1 1.4 1 1 0 1 1 1 0 Polysaccharide lyase family 4, domain III SMP_LBD PF17047.5 KFP03393.1 - 2.4e-65 219.4 0.2 4.1e-65 218.6 0.2 1.4 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 KFP03393.1 - 3.7e-35 120.3 0.1 6.4e-22 77.8 0.0 2.4 2 0 0 2 2 2 2 C2 domain cPLA2_C2 PF18695.1 KFP03393.1 - 0.072 13.1 0.2 0.19 11.7 0.2 1.7 1 0 0 1 1 1 0 Cytosolic phospholipases A2 C2-domain 2OG-FeII_Oxy_4 PF13661.6 KFP03393.1 - 0.15 12.7 0.2 38 5.0 0.0 2.7 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily TackOD1 PF18551.1 KFP03394.1 - 0.074 12.7 0.2 0.16 11.6 0.2 1.5 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 YtxH PF12732.7 KFP03394.1 - 2.4 8.7 4.9 14 6.3 0.3 2.9 2 1 0 2 2 2 0 YtxH-like protein PapD-like PF14874.6 KFP03395.1 - 0.00012 22.2 0.1 0.0002 21.4 0.1 1.3 1 0 0 1 1 1 1 Flagellar-associated PapD-like ASH PF15780.5 KFP03395.1 - 0.022 14.9 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 KFP03395.1 - 0.038 14.3 0.0 0.083 13.1 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 131-like 7tm_2 PF00002.24 KFP03396.1 - 2.7e-91 305.3 16.6 3.9e-91 304.7 16.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFP03396.1 - 2.5e-19 69.3 3.4 2.5e-19 69.3 3.4 1.9 2 0 0 2 2 2 1 Hormone receptor domain Insulin_TMD PF17870.1 KFP03396.1 - 0.066 13.3 0.1 0.19 11.8 0.1 1.8 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment TMEM37 PF15108.6 KFP03397.1 - 2.5e-88 294.7 15.2 2.8e-88 294.6 15.2 1.0 1 0 0 1 1 1 1 Voltage-dependent calcium channel gamma-like subunit protein family DUF2340 PF10209.9 KFP03398.1 - 4.5e-44 149.8 0.0 5e-44 149.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) F420_oxidored PF03807.17 KFP03399.1 - 3e-16 59.8 0.1 1.8e-15 57.3 0.1 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Ferric_reduct PF01794.19 KFP03399.1 - 6.7e-13 48.8 6.8 1.3e-12 48.0 3.7 2.3 1 1 1 2 2 2 2 Ferric reductase like transmembrane component NAD_binding_2 PF03446.15 KFP03399.1 - 7.3e-05 23.0 0.0 0.0003 21.0 0.1 1.9 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KFP03399.1 - 0.0007 19.2 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 KFP03399.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KFP03399.1 - 0.014 15.5 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Malt_amylase_C PF16657.5 KFP03399.1 - 0.14 12.3 0.1 4.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Maltogenic Amylase, C-terminal domain Sacchrp_dh_NADP PF03435.18 KFP03399.1 - 0.25 11.6 0.8 0.7 10.1 0.1 2.2 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain C1q PF00386.21 KFP03400.1 - 1.4e-18 67.3 0.0 1.5e-18 67.2 0.0 1.0 1 0 0 1 1 1 1 C1q domain TNF PF00229.18 KFP03400.1 - 0.036 14.0 0.0 0.039 13.9 0.0 1.1 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family Collagen PF01391.18 KFP03401.1 - 1.2e-36 124.3 123.2 1.2e-09 37.8 25.9 4.8 2 2 2 4 4 4 4 Collagen triple helix repeat (20 copies) SRCR PF00530.18 KFP03401.1 - 1.2e-27 96.4 1.4 1.8e-27 95.7 1.4 1.3 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFP03401.1 - 1.9e-05 25.1 0.0 3.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain MHC2-interact PF09307.10 KFP03401.1 - 0.032 14.2 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 CLIP, MHC2 interacting Hepsin-SRCR PF09272.10 KFP03401.1 - 0.072 13.6 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 Hepsin, SRCR domain INSIG PF07281.12 KFP03402.1 - 2.9e-37 128.4 3.5 3e-36 125.1 3.5 2.1 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) KOG2701 PF09762.9 KFP03403.1 - 3.6e-77 258.6 0.0 3.6e-77 258.6 0.0 4.5 2 1 1 3 3 3 1 Coiled-coil domain-containing protein (DUF2037) Baculo_PEP_C PF04513.12 KFP03403.1 - 0.067 13.2 6.7 0.096 12.7 1.9 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 KFP03403.1 - 0.77 10.3 9.0 3.3 8.2 3.7 3.7 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF2730 PF10805.8 KFP03403.1 - 2.9 8.0 20.6 0.4 10.8 0.8 4.8 4 1 1 5 5 5 0 Protein of unknown function (DUF2730) CorA PF01544.18 KFP03403.1 - 4.4 6.5 23.8 3.1 7.0 3.9 2.6 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.12 KFP03403.1 - 4.9 7.2 24.4 0.31 11.1 1.4 4.8 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) 7tm_1 PF00001.21 KFP03404.1 - 1.7e-70 237.3 8.8 2.2e-70 237.0 8.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP03404.1 - 3.6e-07 30.1 1.2 3.6e-07 30.1 1.2 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFP03404.1 - 1.5e-05 24.5 5.7 4.2e-05 23.0 5.3 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2208 PF09973.9 KFP03404.1 - 0.0016 18.1 2.1 0.0034 17.0 0.0 2.0 2 0 0 2 2 2 1 Predicted membrane protein (DUF2208) 7tm_4 PF13853.6 KFP03404.1 - 0.0035 17.1 1.7 0.0035 17.1 1.7 1.7 2 0 0 2 2 2 1 Olfactory receptor OppC_N PF12911.7 KFP03404.1 - 0.023 14.6 3.4 0.059 13.3 0.0 2.8 2 1 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C ATP11 PF06644.11 KFP03405.1 - 0.072 12.9 0.3 0.08 12.7 0.3 1.0 1 0 0 1 1 1 0 ATP11 protein MBOAT_2 PF13813.6 KFP03405.1 - 0.33 11.2 2.9 0.3 11.4 1.0 1.8 1 1 0 2 2 2 0 Membrane bound O-acyl transferase family DEAD PF00270.29 KFP03406.1 - 3.2e-47 160.5 0.1 6.9e-47 159.5 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP03406.1 - 3e-24 85.5 0.0 9.3e-23 80.7 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFP03406.1 - 4.6e-17 62.0 0.3 8.2e-17 61.2 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KFP03406.1 - 1e-07 32.1 0.0 1.8e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DPPIV_N PF00930.21 KFP03407.1 - 6e-105 350.9 0.2 7.9e-105 350.5 0.2 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KFP03407.1 - 3.9e-50 170.3 0.0 5.9e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KFP03407.1 - 1.1e-07 31.6 0.0 4.1e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KFP03407.1 - 1.9e-05 24.1 0.4 0.17 11.1 0.2 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 PD40 PF07676.12 KFP03407.1 - 0.00011 22.1 0.1 1.6 8.7 0.0 3.3 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Abhydrolase_3 PF07859.13 KFP03407.1 - 0.0071 16.2 0.0 0.13 12.1 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KFP03407.1 - 0.025 14.4 1.6 0.064 13.1 0.1 2.2 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 KFP03407.1 - 0.028 14.0 0.0 2.4 7.7 0.0 2.8 2 1 1 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) Pecanex_C PF05041.15 KFP03407.1 - 0.032 13.8 0.0 0.071 12.7 0.0 1.5 1 0 0 1 1 1 0 Pecanex protein (C-terminus) BAAT_C PF08840.11 KFP03407.1 - 0.04 13.8 0.8 0.22 11.4 0.3 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2920 PF11144.8 KFP03407.1 - 0.041 13.1 0.3 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) FlaC_arch PF05377.11 KFP03408.1 - 0.031 14.7 6.3 0.37 11.2 1.5 3.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) PI_PP_I PF18363.1 KFP03408.1 - 0.95 9.7 5.9 0.38 11.0 1.9 2.3 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain SLATT_6 PF18169.1 KFP03408.1 - 1.3 8.6 3.8 4.8 6.8 3.8 2.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 LRR_4 PF12799.7 KFP03409.1 - 2.1e-06 27.9 1.2 0.0026 18.1 0.1 3.9 2 1 3 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP03409.1 - 6.4e-05 22.6 5.3 0.01 15.6 0.2 3.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 KFP03409.1 - 0.00023 20.7 0.6 0.00056 19.5 0.5 1.5 1 1 0 1 1 1 1 Leucine-rich repeat Serpin PF00079.20 KFP03410.1 - 3e-114 382.2 1.8 3.4e-114 382.0 1.8 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF1280 PF06918.14 KFP03410.1 - 0.027 14.0 0.5 0.047 13.3 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) Rsbr_N PF08678.10 KFP03410.1 - 0.12 12.5 0.9 1.9 8.5 0.2 2.3 2 0 0 2 2 2 0 Rsbr N terminal DUF1241 PF06840.11 KFP03411.1 - 2.1e-63 212.4 3.2 2.9e-63 212.0 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) FH2 PF02181.23 KFP03411.1 - 0.00077 18.7 2.1 0.00077 18.7 2.1 1.5 1 1 0 1 1 1 1 Formin Homology 2 Domain CENP-L PF13092.6 KFP03411.1 - 0.0072 16.5 0.1 0.0088 16.3 0.1 1.3 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 CREPT PF16566.5 KFP03411.1 - 0.018 15.2 0.8 0.032 14.4 0.8 1.5 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Med11 PF10280.9 KFP03411.1 - 0.028 14.9 1.1 0.077 13.5 0.4 2.0 1 1 2 3 3 3 0 Mediator complex protein SabA_adhesion PF18304.1 KFP03411.1 - 0.038 13.2 0.6 0.053 12.7 0.6 1.2 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain DUF5344 PF17279.2 KFP03411.1 - 0.056 14.0 1.5 0.23 12.0 0.5 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5344) DUF4208 PF13907.6 KFP03411.1 - 0.059 13.8 1.1 20 5.7 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4208) SesA PF17107.5 KFP03411.1 - 0.077 13.2 2.4 0.1 12.8 0.9 2.0 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases GCN5L1 PF06320.13 KFP03411.1 - 0.083 13.0 2.0 0.42 10.8 0.8 2.2 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) Syntaxin_2 PF14523.6 KFP03411.1 - 0.11 12.9 5.7 0.39 11.1 5.7 1.9 1 1 0 1 1 1 0 Syntaxin-like protein Sec23_trunk PF04811.15 KFP03411.1 - 0.12 11.9 1.9 1.5 8.3 0.3 2.6 1 1 1 2 2 2 0 Sec23/Sec24 trunk domain TFIIF_beta PF02270.15 KFP03411.1 - 0.12 12.5 0.9 0.39 10.9 0.2 2.2 2 0 0 2 2 2 0 TFIIF, beta subunit HTH domain NAAA-beta PF15508.6 KFP03411.1 - 0.19 12.0 0.7 2.8 8.3 0.1 2.7 3 0 0 3 3 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase KLRAQ PF10205.9 KFP03412.1 - 0.0013 19.0 5.2 0.0016 18.7 5.2 1.2 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein CENP-Q PF13094.6 KFP03412.1 - 0.014 15.6 7.4 0.015 15.5 7.4 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Uso1_p115_C PF04871.13 KFP03412.1 - 0.088 13.2 8.1 0.1 12.9 8.1 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region TMCO5 PF14992.6 KFP03412.1 - 0.096 12.2 6.4 0.099 12.2 6.4 1.0 1 0 0 1 1 1 0 TMCO5 family FapA PF03961.13 KFP03412.1 - 0.11 11.1 2.6 0.11 11.1 2.6 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A LMBR1 PF04791.16 KFP03412.1 - 0.23 10.3 0.7 0.21 10.4 0.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein AChE_tetra PF08674.10 KFP03415.1 - 1.9e-23 81.8 8.5 3.4e-23 81.0 8.5 1.4 1 0 0 1 1 1 1 Acetylcholinesterase tetramerisation domain COesterase PF00135.28 KFP03415.1 - 0.015 14.2 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Pkinase_Tyr PF07714.17 KFP03416.1 - 1.4e-103 345.7 0.0 1.9e-103 345.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RET_CLD1 PF17756.1 KFP03416.1 - 2e-54 183.2 0.0 4.1e-53 179.0 0.0 2.9 3 0 0 3 3 3 1 RET Cadherin like domain 1 RET_CLD3 PF17812.1 KFP03416.1 - 5.7e-53 178.1 0.1 1.2e-52 177.0 0.1 1.6 1 0 0 1 1 1 1 RET Cadherin like domain 3 Pkinase PF00069.25 KFP03416.1 - 6.7e-45 153.5 0.0 1.4e-44 152.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain RET_CLD4 PF17813.1 KFP03416.1 - 1.7e-44 150.4 0.5 7.2e-44 148.4 0.3 2.2 2 0 0 2 2 2 1 RET Cadherin like domain 4 Cadherin PF00028.17 KFP03416.1 - 6.6e-19 68.1 0.1 1.7e-09 38.0 0.0 4.8 4 1 0 4 4 4 2 Cadherin domain Cadherin_2 PF08266.12 KFP03416.1 - 0.013 15.3 0.4 1 9.3 0.0 3.0 3 0 0 3 3 3 0 Cadherin-like RIO1 PF01163.22 KFP03416.1 - 0.03 13.9 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 KFP03416.1 - 0.085 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KFP03416.1 - 0.11 11.4 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain CHGN PF05679.16 KFP03417.1 - 3.6e-83 280.1 0.1 4.8e-83 279.7 0.1 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 KFP03417.1 - 3e-08 33.2 0.2 7.2e-08 32.0 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase KfrA_N PF11740.8 KFP03417.1 - 0.00075 20.2 0.3 0.0014 19.3 0.3 1.4 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term Glyco_tranf_2_2 PF10111.9 KFP03417.1 - 0.0049 16.4 0.4 2 7.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Dsl1_N PF11988.8 KFP03417.1 - 0.038 13.0 0.0 0.066 12.2 0.0 1.3 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 N terminal mCpol PF18182.1 KFP03417.1 - 0.046 14.1 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 minimal CRISPR polymerase domain Prefoldin PF02996.17 KFP03417.1 - 0.066 13.1 2.3 0.2 11.6 2.3 1.8 1 0 0 1 1 1 0 Prefoldin subunit Fmp27_WPPW PF10359.9 KFP03417.1 - 0.07 12.0 1.6 0.1 11.5 1.6 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Atg14 PF10186.9 KFP03417.1 - 0.11 11.6 4.0 0.17 11.0 4.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 KFP03417.1 - 0.15 12.7 2.7 0.38 11.4 2.7 1.6 1 0 0 1 1 1 0 SlyX FapA PF03961.13 KFP03417.1 - 0.32 9.5 1.9 0.49 9.0 1.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 KFP03417.1 - 0.35 11.1 3.7 0.82 9.9 3.7 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4140 PF13600.6 KFP03417.1 - 0.79 10.2 3.3 1.8 9.0 3.3 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Cnn_1N PF07989.11 KFP03417.1 - 1.9 8.7 7.6 0.93 9.7 5.1 1.8 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Csm1_N PF18504.1 KFP03417.1 - 2.8 8.3 8.5 6.1 7.3 8.0 1.8 2 0 0 2 2 1 0 Csm1 N-terminal domain DUF5320 PF17253.2 KFP03417.1 - 7.3 7.7 6.0 0.64 11.1 0.4 2.2 3 0 0 3 3 1 0 Family of unknown function (DUF5320) T2SSM PF04612.12 KFP03417.1 - 8.3 6.4 6.6 12 5.9 1.6 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DUF4407 PF14362.6 KFP03417.1 - 9.1 5.5 8.8 0.18 11.1 1.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RasGEF PF00617.19 KFP03418.1 - 1.7e-46 158.7 3.1 1.7e-46 158.7 3.1 2.2 2 1 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KFP03418.1 - 1.1e-12 48.2 0.2 3.9e-12 46.3 0.1 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif H2TH PF06831.14 KFP03418.1 - 0.065 13.2 0.0 24 5.0 0.0 3.0 2 0 0 2 2 2 0 Formamidopyrimidine-DNA glycosylase H2TH domain VHS PF00790.19 KFP03418.1 - 0.085 12.7 1.6 0.94 9.3 0.2 2.3 1 1 1 2 2 2 0 VHS domain RRT14 PF17075.5 KFP03418.1 - 0.17 12.0 4.0 0.13 12.4 2.4 1.6 2 0 0 2 2 2 0 Regular of rDNA transcription protein 14 Zn-C2H2_12 PF18112.1 KFP03419.1 - 0.15 12.6 0.0 5.2 7.6 0.0 2.1 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Lectin_C PF00059.21 KFP03420.1 - 5e-20 72.3 0.0 5.6e-20 72.1 0.0 1.0 1 0 0 1 1 1 1 Lectin C-type domain E1_4HB PF16191.5 KFP03420.1 - 0.14 12.4 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 four-helix bundle Lectin_C PF00059.21 KFP03421.1 - 1.1e-19 71.2 0.0 1.2e-19 71.0 0.0 1.1 1 0 0 1 1 1 1 Lectin C-type domain S-AdoMet_synt_C PF02773.16 KFP03422.1 - 2.2e-68 228.5 0.1 4.3e-68 227.6 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KFP03422.1 - 4.3e-46 156.1 0.0 8e-46 155.2 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KFP03422.1 - 3.2e-43 146.4 0.5 5.6e-43 145.6 0.1 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 KFP03422.1 - 0.04 12.7 0.2 0.09 11.5 0.2 1.5 1 1 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) Dpy-30 PF05186.13 KFP03423.1 - 2.9e-14 52.5 0.1 4.9e-14 51.7 0.0 1.4 2 0 0 2 2 2 1 Dpy-30 motif RIIa PF02197.17 KFP03423.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit KH_6 PF15985.5 KFP03424.1 - 1.6e-16 60.4 0.0 2.4e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 KH domain Radial_spoke_3 PF06098.11 KFP03425.1 - 0.1 11.8 0.1 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 Tetraspanin PF00335.20 KFP03426.1 - 6e-60 202.8 9.3 6.7e-60 202.6 9.3 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2371 PF10177.9 KFP03426.1 - 0.34 11.1 4.1 13 5.9 1.6 3.0 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Arm PF00514.23 KFP03427.1 - 7.9e-20 70.2 22.0 1.7e-08 34.2 0.3 7.8 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KFP03427.1 - 6.4e-08 32.9 13.6 0.048 14.1 0.0 5.5 3 1 2 5 5 5 4 HEAT repeats V-ATPase_H_C PF11698.8 KFP03427.1 - 3e-06 27.3 11.2 2.7e-05 24.3 0.3 4.5 4 1 1 5 5 5 1 V-ATPase subunit H HEAT PF02985.22 KFP03427.1 - 6.5e-05 22.9 3.5 0.45 10.9 0.1 5.2 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 KFP03427.1 - 8.1e-05 23.0 11.2 1.3 9.6 0.1 6.5 5 2 2 7 7 7 2 HEAT-like repeat Vps39_1 PF10366.9 KFP03427.1 - 0.025 14.9 0.6 0.025 14.9 0.6 4.1 3 2 1 4 4 4 0 Vacuolar sorting protein 39 domain 1 RTTN_N PF14726.6 KFP03427.1 - 0.091 13.6 8.9 4.4 8.2 0.0 4.1 3 2 1 4 4 4 0 Rotatin, an armadillo repeat protein, centriole functioning SapB_1 PF05184.15 KFP03427.1 - 0.22 11.6 1.5 1.4 9.0 0.5 3.1 2 0 0 2 2 2 0 Saposin-like type B, region 1 dsDNA_bind PF01984.20 KFP03427.1 - 1.6 9.0 10.6 0.39 11.0 1.4 3.3 2 1 0 2 2 2 0 Double-stranded DNA-binding domain SH2 PF00017.24 KFP03428.1 - 4e-11 42.9 0.4 1.1e-10 41.4 0.0 1.9 2 0 0 2 2 2 1 SH2 domain DUF5486 PF17588.2 KFP03428.1 - 0.024 14.5 0.9 0.024 14.5 0.9 3.3 4 1 1 5 5 5 0 Family of unknown function (DUF5486) PSCyt2 PF07583.11 KFP03428.1 - 0.24 11.3 8.2 0.23 11.3 6.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1549) Zip PF02535.22 KFP03428.1 - 2.2 7.4 2.9 3.4 6.8 2.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter RVT_1 PF00078.27 KFP03429.1 - 0.0013 18.3 0.0 0.0023 17.5 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Muted PF14942.6 KFP03431.1 - 9.9e-55 184.9 17.2 1.1e-54 184.7 17.2 1.0 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein FliD_C PF07195.12 KFP03431.1 - 0.48 9.8 8.8 1.5 8.2 8.8 1.8 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Nucleoporin_FG2 PF15967.5 KFP03431.1 - 0.97 7.9 2.0 1.2 7.6 2.0 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region UMPH-1 PF05822.12 KFP03431.1 - 1.2 8.6 8.5 2.4 7.6 8.2 1.5 1 1 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) DUF848 PF05852.11 KFP03431.1 - 1.2 9.2 14.6 1.3 9.2 10.6 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF148 PF02520.17 KFP03431.1 - 1.3 9.2 12.7 1.1 9.4 6.6 2.5 1 1 1 2 2 2 0 Domain of unknown function DUF148 DUF3810 PF12725.7 KFP03431.1 - 1.4 8.1 10.0 6.2 6.1 10.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) Exonuc_VII_L PF02601.15 KFP03431.1 - 3 7.3 7.9 3.5 7.1 7.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 KFP03431.1 - 4 5.2 11.2 4.8 5.0 11.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GST_C PF00043.25 KFP03432.1 - 1.6e-07 31.4 0.2 3.6e-07 30.3 0.1 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFP03432.1 - 3.2e-05 24.1 0.1 4.9e-05 23.5 0.1 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFP03432.1 - 0.00036 20.5 0.0 0.0008 19.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain UAA PF08449.11 KFP03433.1 - 1.6e-96 323.1 24.2 1.9e-96 322.8 24.2 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KFP03433.1 - 0.023 14.8 31.0 0.038 14.2 15.8 2.7 2 1 1 3 3 3 0 EamA-like transporter family OFCC1 PF15680.5 KFP03436.1 - 2.2e-57 192.3 2.3 2.2e-57 192.3 2.3 1.4 2 0 0 2 2 2 1 Orofacial cleft 1 candidate gene 1 protein LRRC37AB_C PF14914.6 KFP03436.1 - 0.12 12.3 0.1 0.12 12.3 0.1 1.8 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain LAT2 PF15703.5 KFP03436.1 - 0.16 11.9 3.0 0.3 10.9 2.9 1.6 1 1 0 1 1 1 0 Linker for activation of T-cells family member 2 DUF4193 PF13834.6 KFP03436.1 - 0.65 10.5 4.2 1.8 9.1 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4193) TF_AP-2 PF03299.14 KFP03437.1 - 3.7e-79 265.3 0.0 4.4e-79 265.0 0.0 1.0 1 0 0 1 1 1 1 Transcription factor AP-2 DUF2624 PF11116.8 KFP03437.1 - 0.043 14.7 0.0 0.093 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) Peptidase_Prp PF04327.12 KFP03437.1 - 0.057 13.7 0.0 0.66 10.3 0.0 2.1 2 0 0 2 2 2 0 Cysteine protease Prp Branch PF02485.21 KFP03438.1 - 1.4e-56 191.8 0.0 1.7e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Tmemb_14 PF03647.13 KFP03439.1 - 3.1e-17 63.1 6.7 4.1e-17 62.7 6.7 1.3 1 1 0 1 1 1 1 Transmembrane proteins 14C Pkinase PF00069.25 KFP03440.1 - 5.8e-78 261.9 0.0 7.3e-78 261.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP03440.1 - 6.1e-36 124.0 0.3 2.9e-35 121.8 0.3 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase GCM PF03615.15 KFP03441.1 - 3.7e-72 240.7 1.3 3.7e-72 240.7 1.3 1.7 2 0 0 2 2 2 1 GCM motif protein ELO PF01151.18 KFP03442.1 - 3.3e-60 203.7 23.8 3.7e-60 203.5 23.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CAS_C PF12026.8 KFP03443.1 - 1.8e-80 270.0 7.4 1.8e-80 270.0 7.4 1.9 2 1 1 3 3 3 1 Crk-Associated Substrate C-terminal domain Serine_rich PF08824.10 KFP03443.1 - 2.3e-58 196.7 3.8 2.3e-58 196.7 3.8 2.8 3 0 0 3 3 3 1 Serine rich protein interaction domain SH3_9 PF14604.6 KFP03443.1 - 2.2e-13 49.8 0.0 3.9e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP03443.1 - 3.1e-11 42.7 0.0 5.8e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP03443.1 - 4.3e-11 42.3 0.0 7.6e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Tmemb_170 PF10190.9 KFP03444.1 - 3.9e-36 123.6 12.5 4.3e-36 123.5 12.5 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 Gly_kinase PF02595.15 KFP03444.1 - 0.0035 16.4 0.0 0.0038 16.3 0.0 1.0 1 0 0 1 1 1 1 Glycerate kinase family Far-17a_AIG1 PF04750.14 KFP03445.1 - 4e-61 205.9 15.6 4.6e-61 205.7 15.6 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein zf-C2H2 PF00096.26 KFP03446.1 - 1.9e-18 65.8 41.1 0.00015 22.0 1.6 6.1 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP03446.1 - 1.6e-09 37.7 11.0 8.8e-07 29.1 0.6 5.7 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP03446.1 - 1.5e-07 31.6 35.5 0.038 14.8 1.8 6.0 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP03446.1 - 1.8e-06 28.1 41.1 0.012 15.8 1.4 6.1 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding NOA36 PF06524.12 KFP03446.1 - 0.00036 20.0 21.3 0.0071 15.7 1.1 2.9 3 0 0 3 3 3 2 NOA36 protein zf-H2C2_5 PF13909.6 KFP03446.1 - 0.00087 19.0 5.8 0.00087 19.0 5.8 5.7 5 0 0 5 5 5 3 C2H2-type zinc-finger domain zf-met PF12874.7 KFP03446.1 - 0.22 12.0 38.5 1.4 9.5 0.5 5.7 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Endothelin PF00322.17 KFP03447.1 - 2.1e-23 81.6 14.2 4.4e-20 71.0 4.5 2.4 2 0 0 2 2 2 2 Endothelin family Glyco_hydro_38N PF01074.22 KFP03447.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 N-terminal domain RPEL PF02755.15 KFP03448.1 - 2e-32 109.9 29.0 2.5e-09 36.5 2.9 4.8 4 0 0 4 4 4 4 RPEL repeat Sod_Ni PF09055.11 KFP03448.1 - 0.18 12.4 2.3 0.22 12.1 0.6 2.0 2 0 0 2 2 2 0 Nickel-containing superoxide dismutase RabGAP-TBC PF00566.18 KFP03449.1 - 8.2e-05 22.4 6.1 0.0015 18.2 3.9 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DrrA_P4M PF14860.6 KFP03449.1 - 0.048 13.5 0.1 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain GFO_IDH_MocA PF01408.22 KFP03450.1 - 1.2e-07 32.6 0.0 2.2e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KFP03450.1 - 0.043 13.8 0.2 0.093 12.7 0.2 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Tmemb_14 PF03647.13 KFP03451.1 - 9.4e-22 77.6 3.3 1e-21 77.4 3.3 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C WD40 PF00400.32 KFP03452.1 - 1.2e-24 86.1 4.3 3.5e-06 27.6 0.3 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP03452.1 - 3.3e-09 36.9 2.1 0.0014 18.9 0.0 4.7 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP03452.1 - 7.2e-05 21.9 2.7 0.2 10.6 0.2 3.0 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 KFP03452.1 - 0.00077 19.5 3.6 0.1 12.7 0.1 3.3 3 2 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 KFP03452.1 - 0.0039 16.5 1.0 0.62 9.3 0.0 2.4 1 1 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 KFP03452.1 - 0.0041 15.8 1.4 0.62 8.6 0.1 2.9 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Trnau1ap PF17654.1 KFP03453.1 - 1.4e-29 102.9 24.2 3.7e-29 101.6 24.2 1.6 1 1 0 1 1 1 1 Selenocysteine tRNA 1 associated proteins RRM_1 PF00076.22 KFP03453.1 - 1.5e-10 40.7 0.0 2.5e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_assoc PF14363.6 KFP03453.1 - 0.0026 18.0 2.7 0.74 10.2 1.0 2.2 2 0 0 2 2 2 2 Domain associated at C-terminal with AAA Nup153 PF08604.10 KFP03454.1 - 3.5e-217 722.2 46.5 3.5e-217 722.2 46.5 5.5 2 2 2 5 5 5 1 Nucleoporin Nup153-like zf-RanBP PF00641.18 KFP03454.1 - 1.4e-36 123.5 35.5 4.3e-12 45.1 2.4 4.5 4 0 0 4 4 4 4 Zn-finger in Ran binding protein and others Nup_retrotrp_bd PF10599.9 KFP03454.1 - 2.8e-11 43.9 15.3 2.8e-11 43.9 15.3 12.9 6 4 6 12 12 12 1 Retro-transposon transporting motif Vps36-NZF-N PF16988.5 KFP03454.1 - 2.5 7.6 14.0 6.6 6.2 0.4 4.0 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF3615 PF12274.8 KFP03454.1 - 6.1 7.4 8.2 28 5.3 0.3 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3615) RDD PF06271.12 KFP03455.1 - 6e-12 46.0 5.1 1.6e-10 41.3 5.1 2.0 1 1 0 1 1 1 1 RDD family CAP_N PF01213.19 KFP03456.1 - 5.7e-87 292.1 3.1 1.8e-64 218.2 1.5 2.2 2 0 0 2 2 2 2 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KFP03456.1 - 4.6e-64 214.8 3.8 6.1e-64 214.4 3.8 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 KFP03456.1 - 0.0002 21.1 2.8 0.00047 19.9 2.7 1.6 1 1 0 1 1 1 1 Tubulin binding cofactor C AXH PF08517.12 KFP03457.1 - 2e-42 144.4 0.1 3.8e-42 143.5 0.1 1.5 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) ATXN-1_C PF12547.8 KFP03457.1 - 3.1e-21 75.5 2.7 3.1e-21 75.5 2.7 3.8 3 0 0 3 3 3 1 Capicua transcriptional repressor modulator IMPDH PF00478.25 KFP03458.1 - 1.4e-81 274.2 3.1 4e-81 272.7 3.1 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KFP03458.1 - 7.6e-05 21.9 0.7 0.00013 21.1 0.7 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase FERM_M PF00373.18 KFP03459.1 - 2.1e-16 60.4 1.5 4.4e-16 59.4 1.5 1.5 1 0 0 1 1 1 1 FERM central domain zf-C3HC4_3 PF13920.6 KFP03459.1 - 4.6e-11 42.4 20.5 1.2e-10 41.1 20.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FERM_N PF09379.10 KFP03459.1 - 6e-09 35.7 0.0 1.3e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 FERM N-terminal domain FERM_C PF09380.10 KFP03459.1 - 1.9e-05 25.0 0.0 6.8e-05 23.2 0.0 1.9 2 1 0 2 2 2 1 FERM C-terminal PH-like domain Prok-RING_4 PF14447.6 KFP03459.1 - 0.0039 17.0 21.5 0.011 15.5 21.5 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Rab_eff_C PF04698.12 KFP03459.1 - 3.8 5.7 5.2 0.42 8.8 0.3 1.7 2 0 0 2 2 2 0 Rab effector MyRIP/melanophilin C-terminus Dysbindin PF04440.16 KFP03460.1 - 1.2e-67 226.6 10.1 2.4e-67 225.6 10.1 1.5 1 0 0 1 1 1 1 Dysbindin (Dystrobrevin binding protein 1) DUF4829 PF16111.5 KFP03460.1 - 0.11 13.3 0.7 0.61 10.9 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4829) DUF2730 PF10805.8 KFP03460.1 - 0.21 11.7 0.1 0.21 11.7 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) AIP3 PF03915.13 KFP03460.1 - 0.25 10.4 13.7 0.064 12.3 10.1 1.7 2 0 0 2 2 2 0 Actin interacting protein 3 JmjC PF02373.22 KFP03461.1 - 7.6e-22 77.9 1.2 1.1e-20 74.1 0.7 3.0 2 1 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.21 KFP03461.1 - 7.7e-13 48.9 0.0 2.8e-12 47.1 0.0 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 KFP03461.1 - 7.7e-13 48.2 0.0 3e-12 46.3 0.1 2.0 2 0 0 2 2 2 1 jmjN domain zf-C5HC2 PF02928.16 KFP03461.1 - 3.7e-08 33.6 7.1 9.8e-08 32.3 7.1 1.8 1 0 0 1 1 1 1 C5HC2 zinc finger zf-C3HC4_2 PF13923.6 KFP03461.1 - 7.3 6.5 7.9 20 5.1 7.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP03462.1 - 2.9e-07 30.7 9.4 2.9e-07 30.7 9.4 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KFP03462.1 - 1.3e-05 25.1 9.9 1.3e-05 25.1 9.9 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFP03462.1 - 0.0003 20.6 9.8 0.00075 19.3 9.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP03462.1 - 0.00032 20.7 7.3 0.0012 18.8 7.3 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFP03462.1 - 0.036 14.2 9.9 0.17 12.0 9.7 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFP03462.1 - 0.071 13.0 10.9 0.19 11.6 10.9 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FYVE PF01363.21 KFP03462.1 - 0.14 12.3 9.8 0.32 11.2 9.8 1.6 1 0 0 1 1 1 0 FYVE zinc finger DUF1640 PF07798.11 KFP03463.1 - 9.8e-62 208.1 11.5 1.1e-61 207.9 11.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) YscO-like PF16789.5 KFP03463.1 - 0.027 14.5 6.5 0.027 14.5 6.5 2.0 1 1 1 2 2 2 0 YscO-like protein PID PF00640.23 KFP03463.1 - 0.21 11.6 3.7 0.11 12.5 0.7 1.8 1 1 1 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) Baculo_PEP_C PF04513.12 KFP03463.1 - 2.3 8.3 10.0 1 9.4 5.5 2.1 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 KFP03463.1 - 2.5 8.6 7.7 1.2 9.6 2.1 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) YabA PF06156.13 KFP03463.1 - 7.1 7.3 10.7 90 3.8 10.2 2.4 1 1 0 1 1 1 0 Initiation control protein YabA CLTH PF10607.9 KFP03464.1 - 4.5e-48 162.9 0.1 6.5e-48 162.4 0.1 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 KFP03464.1 - 1.9e-25 89.3 0.2 4e-25 88.3 0.2 1.6 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 KFP03464.1 - 1.3e-06 28.2 0.0 3e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 LisH SIR2 PF02146.17 KFP03465.1 - 7e-49 166.1 0.0 1.1e-48 165.5 0.0 1.3 1 0 0 1 1 1 1 Sir2 family PNTB PF02233.16 KFP03465.1 - 0.00024 20.2 0.1 0.0035 16.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit TPP_enzyme_M PF00205.22 KFP03465.1 - 0.12 12.1 0.0 18 5.0 0.0 2.6 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain Kinesin PF00225.23 KFP03466.1 - 1.7e-106 355.9 0.2 3.3e-106 355.0 0.2 1.5 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 KFP03466.1 - 2.3e-29 103.0 0.0 9.4e-29 101.1 0.0 2.1 1 1 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 KFP03466.1 - 4.2e-24 85.7 22.8 2e-19 70.4 2.2 4.1 4 1 1 5 5 5 2 Kinesin-associated CAP_GLY PF01302.25 KFP03466.1 - 2.1e-23 82.1 1.8 6.5e-23 80.5 1.7 1.9 2 0 0 2 2 2 1 CAP-Gly domain Microtub_bd PF16796.5 KFP03466.1 - 2.3e-21 76.3 0.0 7.5e-21 74.6 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 KFP03466.1 - 2.5e-16 59.8 0.0 8.2e-16 58.2 0.0 2.0 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.26 KFP03466.1 - 6.9e-05 23.1 0.1 0.00098 19.4 0.0 2.5 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KFP03466.1 - 0.0042 17.4 0.0 0.015 15.6 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Dynamin_N PF00350.23 KFP03466.1 - 0.019 15.0 1.7 0.34 10.9 0.0 3.4 3 0 0 3 3 3 0 Dynamin family KMP11 PF03037.16 KFP03466.1 - 0.22 12.3 7.7 0.26 12.1 1.4 2.9 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 CSN5_C PF18323.1 KFP03466.1 - 1.9 9.5 4.5 9.1 7.3 0.1 3.2 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Fib_alpha PF08702.10 KFP03466.1 - 5 7.3 16.6 11 6.2 2.0 4.2 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family NHL PF01436.21 KFP03467.1 - 3.3e-20 71.0 6.5 0.00092 19.1 0.0 6.4 6 0 0 6 6 6 6 NHL repeat SGL PF08450.12 KFP03467.1 - 0.068 12.7 0.0 0.97 9.0 0.0 2.5 1 1 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region PQQ_3 PF13570.6 KFP03467.1 - 2.7 8.6 4.6 1.5 9.4 0.4 2.7 4 0 0 4 4 4 0 PQQ-like domain TPMT PF05724.11 KFP03468.1 - 2.4e-68 230.1 0.0 2.8e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 KFP03468.1 - 0.027 15.1 0.0 0.082 13.6 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KFP03468.1 - 0.038 14.7 0.0 0.42 11.4 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Amino_oxidase PF01593.24 KFP03469.1 - 3.6e-90 303.4 0.0 5.2e-90 302.9 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFP03469.1 - 4.4e-12 46.0 0.1 1.1e-11 44.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain zf-CW PF07496.15 KFP03469.1 - 5.4e-11 42.3 1.9 2.1e-10 40.5 1.9 2.1 1 0 0 1 1 1 1 CW-type Zinc Finger SWIRM PF04433.17 KFP03469.1 - 3.1e-08 33.9 0.1 7.6e-08 32.6 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain Pyr_redox PF00070.27 KFP03469.1 - 1e-07 32.4 0.4 2.3e-05 24.9 0.2 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFP03469.1 - 2.3e-07 30.3 0.1 5.9e-07 29.0 0.1 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KFP03469.1 - 4e-07 29.6 0.2 2e-05 24.0 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFP03469.1 - 1.4e-06 27.3 0.9 6.8e-05 21.7 0.4 2.9 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 KFP03469.1 - 6.4e-06 25.5 0.8 6.1e-05 22.3 0.9 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KFP03469.1 - 1.2e-05 24.7 1.5 0.0024 17.2 0.6 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFP03469.1 - 2.4e-05 23.8 0.2 0.00029 20.2 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KFP03469.1 - 7e-05 22.6 2.4 0.00061 19.5 2.4 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFP03469.1 - 0.0001 21.5 0.1 0.00041 19.5 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KFP03469.1 - 0.00041 19.8 0.0 0.0012 18.2 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KFP03469.1 - 0.00045 20.2 0.6 0.11 12.5 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KFP03469.1 - 0.0009 18.7 0.1 0.0016 17.9 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KFP03469.1 - 0.006 15.7 0.5 0.0098 15.0 0.5 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KFP03469.1 - 0.0099 15.2 0.1 0.018 14.3 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 KFP03469.1 - 0.018 14.6 0.2 0.031 13.9 0.2 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain YjeF_N PF03853.15 KFP03469.1 - 0.067 13.1 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus NAD_binding_7 PF13241.6 KFP03469.1 - 0.082 13.4 3.0 0.11 13.0 0.2 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding zf-C3HC4 PF00097.25 KFP03469.1 - 0.099 12.5 4.0 0.39 10.6 4.0 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Attractin PF08037.11 KFP03469.1 - 0.11 12.5 2.1 0.51 10.4 2.1 2.1 1 0 0 1 1 1 0 Attractin family zf-RING_2 PF13639.6 KFP03469.1 - 4.3 7.7 12.8 0.39 11.1 7.3 2.2 2 0 0 2 2 1 0 Ring finger domain DEK_C PF08766.11 KFP03470.1 - 5.3e-18 64.7 0.3 1.2e-17 63.5 0.3 1.7 1 0 0 1 1 1 1 DEK C terminal domain SAP PF02037.27 KFP03470.1 - 5.7e-06 26.0 1.6 1.6e-05 24.5 0.1 2.7 2 0 0 2 2 2 1 SAP domain Nucleolin_bd PF16725.5 KFP03470.1 - 0.018 14.7 0.2 0.068 12.8 0.1 2.1 2 0 0 2 2 2 0 Nucleolin binding domain Nop14 PF04147.12 KFP03470.1 - 0.074 11.3 40.4 0.27 9.4 12.3 2.1 2 0 0 2 2 2 0 Nop14-like family DUF2052 PF09747.9 KFP03470.1 - 0.75 9.9 35.9 3.2 7.8 16.5 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) ORC6 PF05460.13 KFP03470.1 - 1.6 7.9 35.2 0.023 14.0 21.8 2.1 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) CDC45 PF02724.14 KFP03470.1 - 5.4 5.2 36.4 1.1 7.5 8.8 2.2 2 0 0 2 2 2 0 CDC45-like protein CCSAP PF15748.5 KFP03470.1 - 6.6 6.8 37.6 1.2 9.2 8.4 2.4 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Apt1 PF10351.9 KFP03470.1 - 7.9 5.2 30.3 0.36 9.6 17.4 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain IBR PF01485.21 KFP03471.1 - 1.6e-19 69.8 20.3 1.4e-13 50.8 7.2 4.6 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KFP03471.1 - 0.044 14.1 57.2 0.044 14.1 8.4 5.0 4 1 0 4 4 4 0 Ring finger domain RVT_1 PF00078.27 KFP03472.1 - 0.038 13.5 0.0 0.044 13.3 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) HLH PF00010.26 KFP03473.1 - 4.1e-14 52.3 0.1 5.9e-14 51.8 0.1 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RAMP PF04901.13 KFP03474.1 - 1.1e-44 150.9 3.2 1.2e-44 150.7 3.2 1.0 1 0 0 1 1 1 1 Receptor activity modifying family LRRNT PF01462.18 KFP03474.1 - 0.13 11.9 0.1 0.37 10.5 0.1 1.8 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Guanylate_cyc PF00211.20 KFP03477.1 - 5.1e-131 433.6 0.7 1.3e-66 223.7 0.2 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 KFP03477.1 - 9.5e-34 117.2 3.1 9.5e-34 117.2 3.1 2.3 3 0 0 3 3 3 1 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF1053 PF06327.14 KFP03477.1 - 0.022 15.3 0.3 0.041 14.4 0.3 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) HNOBA PF07701.14 KFP03477.1 - 0.082 12.3 1.6 0.39 10.1 0.3 2.2 2 0 0 2 2 2 0 Heme NO binding associated TBK1_ULD PF18396.1 KFP03477.1 - 0.12 12.4 0.4 0.52 10.3 0.0 2.2 3 0 0 3 3 3 0 TANK binding kinase 1 ubiquitin-like domain Thyroglobulin_1 PF00086.18 KFP03479.1 - 1.2e-21 76.1 4.4 2.2e-21 75.3 4.4 1.4 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat 7tm_4 PF13853.6 KFP03480.1 - 1.1e-42 146.7 8.0 1.3e-42 146.5 8.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP03480.1 - 8.3e-27 94.2 8.7 1.5e-26 93.3 8.7 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP03480.1 - 0.0023 17.4 8.6 0.004 16.6 8.1 1.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx zf-H2C2_2 PF13465.6 KFP03481.1 - 2.2e-51 170.1 71.0 1e-09 38.3 0.5 8.7 9 0 0 9 9 8 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFP03481.1 - 4.5e-42 140.2 67.3 5.3e-06 26.6 3.5 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP03481.1 - 3.4e-23 80.3 64.0 0.0015 19.2 0.1 8.3 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFP03481.1 - 5.2e-12 45.3 39.2 0.0012 18.6 0.1 7.6 8 0 0 8 8 7 4 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KFP03481.1 - 1.4e-11 44.3 32.7 0.0071 16.4 1.4 6.3 3 2 3 6 6 6 5 Zinc ribbon domain zf-C2H2_jaz PF12171.8 KFP03481.1 - 7.7e-10 38.8 28.8 0.088 13.1 0.3 8.1 8 0 0 8 8 8 3 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFP03481.1 - 2.4e-09 36.6 30.1 0.46 10.1 0.0 8.2 8 0 0 8 8 8 4 Ubiquitin-Binding Zinc Finger zf-trcl PF13451.6 KFP03481.1 - 3e-09 36.6 22.1 0.016 15.1 0.0 7.4 7 1 1 8 8 8 3 Probable zinc-ribbon domain zf-LYAR PF08790.11 KFP03481.1 - 1.1e-08 34.8 31.5 1.5 8.8 0.1 8.3 8 0 0 8 8 8 5 LYAR-type C2HC zinc finger XPA_N PF01286.18 KFP03481.1 - 2.5e-08 33.8 28.1 0.4 10.8 0.1 8.3 8 1 0 8 8 8 3 XPA protein N-terminal zinc_ribbon_9 PF14369.6 KFP03481.1 - 2.2e-07 31.0 20.0 0.057 13.7 0.1 7.1 7 0 0 7 7 7 2 zinc-ribbon zf-C2H2_6 PF13912.6 KFP03481.1 - 3.7e-07 30.0 52.1 0.021 14.8 0.6 8.9 9 0 0 9 9 8 3 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 KFP03481.1 - 4.7e-07 29.6 30.6 0.0052 16.7 2.8 6.1 5 1 1 6 6 6 2 SprT-like zinc ribbon domain DUF2256 PF10013.9 KFP03481.1 - 5.2e-06 26.5 22.0 1.5 9.0 0.0 7.6 8 0 0 8 8 8 2 Uncharacterized protein conserved in bacteria (DUF2256) DUF3268 PF11672.8 KFP03481.1 - 9.7e-06 25.9 14.5 0.032 14.6 0.3 4.2 4 0 0 4 4 4 2 zinc-finger-containing domain HypA PF01155.19 KFP03481.1 - 1.5e-05 25.0 18.8 0.043 13.8 1.8 4.4 1 1 3 4 4 4 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Di19 PF05605.12 KFP03481.1 - 3.2e-05 24.1 12.2 0.0015 18.8 2.6 5.8 2 1 5 7 7 7 2 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.7 KFP03481.1 - 4.9e-05 23.3 26.7 8 6.6 14.5 5.0 1 1 1 2 2 2 0 Double zinc ribbon FYDLN_acid PF09538.10 KFP03481.1 - 0.00045 20.8 13.9 7.2 7.3 0.1 6.3 1 1 5 7 7 7 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_15 PF17032.5 KFP03481.1 - 0.00087 20.0 22.3 0.25 12.1 0.6 4.5 1 1 2 4 4 4 2 zinc-ribbon family HNH PF01844.23 KFP03481.1 - 0.0014 18.8 39.9 2.6 8.3 1.0 7.8 8 0 0 8 8 8 3 HNH endonuclease zf-HIT PF04438.16 KFP03481.1 - 0.0035 17.2 31.3 0.77 9.7 0.3 7.1 7 0 0 7 7 7 2 HIT zinc finger YhfH PF14149.6 KFP03481.1 - 0.0054 16.7 25.2 7.4 6.6 0.1 7.5 8 0 0 8 8 8 0 YhfH-like protein DUF2039 PF10217.9 KFP03481.1 - 0.013 15.9 0.3 0.013 15.9 0.3 4.0 1 1 2 4 4 3 0 Uncharacterized conserved protein (DUF2039) TerY_C PF15616.6 KFP03481.1 - 0.014 15.5 10.9 0.15 12.1 1.0 3.5 2 1 1 3 3 3 0 TerY-C metal binding domain zinc-ribbons_6 PF07191.12 KFP03481.1 - 0.022 14.7 25.8 0.41 10.7 1.2 5.6 1 1 2 3 3 3 0 zinc-ribbons DNA_RNApol_7kD PF03604.13 KFP03481.1 - 0.028 14.1 24.3 12 5.7 0.1 7.6 8 0 0 8 8 8 0 DNA directed RNA polymerase, 7 kDa subunit GAGA PF09237.11 KFP03481.1 - 0.042 13.6 7.7 2.5 8.0 0.2 3.5 1 1 2 3 3 3 0 GAGA factor zf-C2HC_2 PF13913.6 KFP03481.1 - 0.13 12.2 0.1 0.13 12.2 0.1 6.8 8 1 0 8 8 5 0 zinc-finger of a C2HC-type TFIIS_C PF01096.18 KFP03481.1 - 0.13 12.1 38.3 3.3 7.6 0.6 7.6 7 2 0 7 7 7 0 Transcription factor S-II (TFIIS) C1_4 PF07975.12 KFP03481.1 - 0.15 12.3 29.3 4.5 7.6 1.0 6.0 2 1 5 7 7 7 0 TFIIH C1-like domain Arc_trans_TRASH PF08394.10 KFP03481.1 - 0.21 12.0 14.6 61 4.1 0.3 6.8 6 2 0 6 6 6 0 Archaeal TRASH domain HalOD2 PF18547.1 KFP03481.1 - 0.22 11.4 25.2 0.32 10.9 0.8 6.2 5 1 1 6 6 6 0 Halobacterial output domain 2 zf-RING_7 PF02591.15 KFP03481.1 - 0.36 11.1 21.7 3.2 8.0 0.1 6.4 7 0 0 7 7 6 0 C4-type zinc ribbon domain PyrI_C PF02748.15 KFP03481.1 - 0.42 10.5 0.2 0.42 10.5 0.2 6.4 5 2 2 7 7 7 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain CpXC PF14353.6 KFP03481.1 - 0.47 10.5 24.8 24 5.0 2.1 6.7 1 1 5 7 7 7 0 CpXC protein TF_Zn_Ribbon PF08271.12 KFP03481.1 - 0.48 10.0 24.5 4.8 6.8 2.5 6.2 6 1 0 6 6 6 0 TFIIB zinc-binding zf-C2HE PF16278.5 KFP03481.1 - 1.4 9.4 38.7 0.8 10.2 0.1 6.9 2 1 4 6 6 5 0 C2HE / C2H2 / C2HC zinc-binding finger OGG_N PF07934.12 KFP03481.1 - 1.5 8.9 4.4 6 7.0 0.6 2.9 1 1 1 2 2 2 0 8-oxoguanine DNA glycosylase, N-terminal domain zf-FPG_IleRS PF06827.14 KFP03481.1 - 5.8 6.9 15.6 43 4.1 0.2 5.2 4 1 0 4 4 4 0 Zinc finger found in FPG and IleRS PknG_rubred PF16919.5 KFP03481.1 - 8.6 6.5 19.9 0.99 9.6 1.1 4.5 2 1 3 5 5 5 0 Protein kinase G rubredoxin domain Pou PF00157.17 KFP03482.1 - 6.5e-24 83.7 2.6 3.4e-14 52.6 0.1 3.0 3 0 0 3 3 3 2 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KFP03482.1 - 1.1e-17 63.6 0.9 1.1e-17 63.6 0.9 2.1 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KFP03482.1 - 0.0067 16.3 0.2 0.052 13.5 0.0 2.4 2 0 0 2 2 2 1 Homeobox KN domain HOCHOB PF17943.1 KFP03482.1 - 0.0078 16.9 0.1 0.016 15.9 0.1 1.4 1 0 0 1 1 1 1 Homeobox-cysteine loop-homeobox FtsX_ECD PF18075.1 KFP03482.1 - 0.069 13.8 0.0 0.069 13.8 0.0 3.0 3 0 0 3 3 3 0 FtsX extracellular domain CLN3 PF02487.17 KFP03482.1 - 0.28 10.2 3.8 0.61 9.1 3.8 1.5 1 0 0 1 1 1 0 CLN3 protein DUF4179 PF13786.6 KFP03482.1 - 0.42 11.1 1.5 2.4 8.7 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) Macoilin PF09726.9 KFP03482.1 - 2.8 6.4 16.3 0.37 9.3 8.0 2.2 2 0 0 2 2 2 0 Macoilin family DUF2052 PF09747.9 KFP03482.1 - 5.8 7.0 12.1 12 6.0 12.1 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Yae1_N PF09811.9 KFP03483.1 - 1.4e-13 50.3 1.7 2.1e-13 49.7 1.7 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal DUF2385 PF09539.10 KFP03483.1 - 0.042 14.4 0.0 0.24 11.9 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2385) Ras PF00071.22 KFP03484.1 - 7.8e-56 188.1 0.3 9.3e-56 187.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP03484.1 - 1.7e-19 70.2 0.0 3.1e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP03484.1 - 2e-10 40.4 0.0 2.6e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFP03484.1 - 7.1e-09 35.8 0.1 5.3e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFP03484.1 - 6.9e-05 22.5 0.2 0.0002 20.9 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFP03484.1 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KFP03484.1 - 0.01 15.2 0.1 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_25 PF13481.6 KFP03484.1 - 0.012 15.2 0.2 0.055 13.0 0.1 1.9 1 1 1 2 2 2 0 AAA domain ThiF PF00899.21 KFP03484.1 - 0.11 11.8 2.0 0.18 11.1 0.1 2.1 2 0 0 2 2 2 0 ThiF family MeaB PF03308.16 KFP03484.1 - 0.15 11.0 0.4 2 7.3 0.3 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CoA_transf_3 PF02515.17 KFP03485.1 - 5.2e-64 216.7 0.0 6.4e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III LRR_8 PF13855.6 KFP03486.1 - 2.9e-16 59.0 14.5 2.6e-11 43.1 7.0 2.6 1 1 1 2 2 2 2 Leucine rich repeat GPS PF01825.21 KFP03486.1 - 1.4e-07 32.0 0.0 1.4e-07 32.0 0.0 3.2 4 0 0 4 4 4 1 GPCR proteolysis site, GPS, motif I-set PF07679.16 KFP03486.1 - 2.1e-06 27.7 0.0 5.6e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_4 PF12799.7 KFP03486.1 - 3.2e-05 24.2 10.3 0.00084 19.7 1.5 2.9 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP03486.1 - 0.00033 20.6 0.1 0.00098 19.1 0.1 1.8 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) ig PF00047.25 KFP03486.1 - 0.0008 19.5 0.2 0.0022 18.1 0.1 1.9 2 0 0 2 2 2 1 Immunoglobulin domain HRM PF02793.22 KFP03486.1 - 0.0011 19.2 1.0 0.003 17.8 1.0 1.8 1 0 0 1 1 1 1 Hormone receptor domain LRR_1 PF00560.33 KFP03486.1 - 0.0056 17.0 5.0 0.56 11.0 0.3 3.7 2 0 0 2 2 2 1 Leucine Rich Repeat LRR_9 PF14580.6 KFP03486.1 - 0.029 13.9 0.3 0.054 13.0 0.3 1.4 1 0 0 1 1 1 0 Leucine-rich repeat EF-hand_7 PF13499.6 KFP03487.1 - 1.3e-25 89.6 4.3 9.1e-19 67.7 0.3 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFP03487.1 - 2.8e-22 76.6 8.3 3.4e-08 32.5 0.2 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KFP03487.1 - 6.2e-19 66.3 7.8 5.8e-06 25.8 0.1 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KFP03487.1 - 1.1e-17 62.6 3.7 9.6e-06 24.9 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KFP03487.1 - 3e-13 49.4 9.9 1.6e-05 24.6 1.7 3.8 2 1 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFP03487.1 - 1.1e-08 35.4 2.3 1.3e-05 25.4 0.4 3.3 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFP03487.1 - 0.00016 21.6 2.8 0.0086 16.0 0.3 2.9 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFP03487.1 - 0.0011 19.2 0.3 6.6 7.1 0.1 3.4 2 1 0 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 KFP03487.1 - 0.0032 17.6 0.2 0.2 11.9 0.0 2.4 1 1 1 2 2 2 2 Dockerin type I domain Caleosin PF05042.13 KFP03487.1 - 0.04 13.9 6.2 3.4 7.6 0.1 3.2 2 1 1 3 3 3 0 Caleosin related protein ParcG PF10274.9 KFP03488.1 - 1.3e-47 162.3 0.0 1.7e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein LRR_8 PF13855.6 KFP03489.1 - 2.6e-90 296.1 84.2 1.3e-13 50.5 0.0 10.2 4 4 6 10 10 10 10 Leucine rich repeat LRR_5 PF13306.6 KFP03489.1 - 1.5e-32 112.2 10.7 4.3e-09 36.4 0.1 5.1 6 0 0 6 6 4 4 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFP03489.1 - 2.2e-31 107.4 63.6 3.3e-05 24.2 0.1 12.1 7 5 8 16 16 16 11 Leucine Rich repeats (2 copies) EGF PF00008.27 KFP03489.1 - 1.9e-28 98.4 89.8 4.1e-08 33.4 7.7 8.1 8 0 0 8 8 7 5 EGF-like domain LRRNT PF01462.18 KFP03489.1 - 2.3e-22 78.1 30.9 1.7e-08 33.9 3.3 6.8 5 0 0 5 5 5 3 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 KFP03489.1 - 3.6e-22 78.7 16.1 6.3e-07 29.1 0.5 4.6 4 1 0 4 4 4 4 Leucine-rich repeat Laminin_G_1 PF00054.23 KFP03489.1 - 9.2e-18 64.7 0.0 1.5e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain LRRCT PF01463.24 KFP03489.1 - 1.8e-17 62.4 8.1 0.0026 18.2 0.1 6.1 6 0 0 6 6 5 4 Leucine rich repeat C-terminal domain Laminin_G_2 PF02210.24 KFP03489.1 - 2.6e-15 57.1 0.0 4.8e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain hEGF PF12661.7 KFP03489.1 - 4.9e-11 42.8 38.5 1.1e-06 29.0 5.7 9.6 11 0 0 11 11 8 5 Human growth factor-like EGF LRR_1 PF00560.33 KFP03489.1 - 3.7e-05 23.7 45.0 2.6 9.0 0.6 14.3 16 2 0 16 16 16 3 Leucine Rich Repeat FXa_inhibition PF14670.6 KFP03489.1 - 0.0007 19.8 4.2 0.0007 19.8 4.2 7.0 4 2 2 6 6 5 3 Coagulation Factor Xa inhibitory site TPKR_C2 PF16920.5 KFP03489.1 - 3.4 7.9 19.4 7.8 6.7 0.5 6.4 6 0 0 6 6 5 0 Tyrosine-protein kinase receptor C2 Ig-like domain RFX_DNA_binding PF02257.15 KFP03491.1 - 4.2e-34 117.0 0.1 1e-33 115.8 0.1 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain RFX1_trans_act PF04589.13 KFP03491.1 - 5.9e-16 59.1 11.5 5.9e-16 59.1 11.5 1.8 2 0 0 2 2 2 1 RFX1 transcription activation region Pox_D5 PF03288.16 KFP03491.1 - 0.039 14.4 0.0 0.078 13.5 0.0 1.4 1 0 0 1 1 1 0 Poxvirus D5 protein-like RVT_1 PF00078.27 KFP03492.1 - 2.8e-17 63.0 0.0 4e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFP03494.1 - 0.072 12.6 0.0 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Cadherin PF00028.17 KFP03497.1 - 9.3e-103 336.9 11.3 6.2e-20 71.5 0.1 7.4 7 0 0 7 7 7 7 Cadherin domain Protocadherin PF08374.11 KFP03497.1 - 2.3e-75 253.3 0.2 4.2e-75 252.5 0.2 1.4 1 0 0 1 1 1 1 Protocadherin Cadherin_2 PF08266.12 KFP03497.1 - 1.6e-20 72.7 0.0 2e-08 34.0 0.0 6.1 6 0 0 6 6 6 4 Cadherin-like Cadherin_3 PF16184.5 KFP03497.1 - 1.6e-09 37.7 17.6 0.19 11.7 0.1 6.2 6 0 0 6 6 6 5 Cadherin-like RET_CLD1 PF17756.1 KFP03497.1 - 0.00026 21.3 0.0 0.27 11.5 0.0 3.2 3 1 0 3 3 3 1 RET Cadherin like domain 1 Cadherin_4 PF17803.1 KFP03497.1 - 0.00036 21.1 24.5 0.03 14.9 0.6 5.6 5 0 0 5 5 5 3 Bacterial cadherin-like domain EphA2_TM PF14575.6 KFP03497.1 - 0.0031 18.4 0.3 0.0073 17.2 0.3 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Invasin_D3 PF09134.10 KFP03497.1 - 0.0034 17.7 8.1 2.7 8.4 0.0 5.4 4 1 1 5 5 5 1 Invasin, domain 3 Big_9 PF17963.1 KFP03497.1 - 0.006 17.3 32.4 0.072 13.8 0.4 6.3 6 0 0 6 6 6 2 Bacterial Ig domain AP3D1 PF06375.11 KFP03497.1 - 0.019 15.2 0.1 0.042 14.1 0.1 1.5 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 V_ATPase_I PF01496.19 KFP03497.1 - 0.041 11.8 0.0 0.059 11.3 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family He_PIG PF05345.12 KFP03497.1 - 0.072 13.3 9.8 22 5.3 0.0 5.6 5 1 0 5 5 5 0 Putative Ig domain Shisa PF13908.6 KFP03497.1 - 0.08 13.2 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Yae1_N PF09811.9 KFP03499.1 - 1.6e-10 40.5 40.1 1.5e+02 2.2 33.7 4.7 2 1 0 2 2 2 2 Essential protein Yae1, N terminal IRK_C PF17655.1 KFP03500.1 - 2.4e-65 219.4 0.2 3.5e-65 218.8 0.2 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFP03500.1 - 2.3e-57 192.8 1.3 4.1e-57 192.0 1.3 1.4 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 KFP03500.1 - 0.0031 17.4 2.7 0.0072 16.3 2.7 1.6 1 1 0 1 1 1 1 Ion channel Ets PF00178.22 KFP03501.1 - 2e-36 124.3 0.4 3.8e-36 123.4 0.4 1.5 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 KFP03501.1 - 2.1e-26 91.7 0.0 4.3e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.17 KFP03501.1 - 0.0077 16.3 0.1 0.081 13.0 0.1 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_3 PF18016.1 KFP03501.1 - 0.019 14.8 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFP03501.1 - 0.082 13.4 0.2 0.22 12.0 0.2 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Ets PF00178.22 KFP03502.1 - 1.2e-36 125.0 1.1 1.2e-36 125.0 1.1 2.0 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.16 KFP03502.1 - 2.3e-34 117.2 1.4 4.5e-34 116.3 1.4 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PAC1 PF16094.5 KFP03503.1 - 1.1e-98 330.0 0.5 1.2e-98 329.8 0.5 1.0 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Bromodomain PF00439.25 KFP03504.1 - 4.8e-38 129.1 0.1 6.3e-18 64.6 0.0 2.7 2 0 0 2 2 2 2 Bromodomain WD40 PF00400.32 KFP03504.1 - 3.5e-37 125.8 14.9 4.7e-06 27.2 0.6 8.8 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP03504.1 - 1.2e-08 35.2 0.6 0.053 13.8 0.1 5.5 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP03504.1 - 0.011 15.7 0.1 0.76 9.6 0.0 2.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KFP03504.1 - 0.054 12.1 1.5 0.69 8.5 0.1 2.6 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Auxin_resp PF06507.13 KFP03504.1 - 0.13 12.6 0.0 0.61 10.4 0.0 2.2 1 0 0 1 1 1 0 Auxin response factor WD40_like PF17005.5 KFP03504.1 - 0.22 10.8 0.0 5.9 6.1 0.0 2.7 3 0 0 3 3 3 0 WD40-like domain HMG14_17 PF01101.18 KFP03505.1 - 1.1e-22 80.8 21.8 1.2e-22 80.7 21.8 1.0 1 0 0 1 1 1 1 HMG14 and HMG17 F-112 PF09645.10 KFP03505.1 - 0.044 13.9 1.0 0.046 13.8 1.0 1.1 1 0 0 1 1 1 0 F-112 protein CHD5 PF04420.14 KFP03506.1 - 3.2e-36 124.6 0.5 3.5e-36 124.5 0.5 1.0 1 0 0 1 1 1 1 CHD5-like protein DUF1043 PF06295.12 KFP03506.1 - 0.0058 16.6 0.6 0.0073 16.3 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) DUF2203 PF09969.9 KFP03506.1 - 0.012 16.4 1.1 0.54 11.0 0.4 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Lectin_N PF03954.14 KFP03506.1 - 0.07 12.9 0.5 0.11 12.3 0.5 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain MCU PF04678.13 KFP03506.1 - 0.11 12.6 4.2 0.6 10.2 4.2 1.8 1 1 0 1 1 1 0 Mitochondrial calcium uniporter THOC7 PF05615.13 KFP03506.1 - 0.2 12.0 3.3 0.27 11.5 3.3 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 DUF1640 PF07798.11 KFP03506.1 - 0.3 11.1 5.9 0.72 9.9 5.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) SH3BGR PF04908.15 KFP03508.1 - 1.5e-47 159.8 0.1 1.7e-47 159.6 0.1 1.0 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 KFP03508.1 - 0.0004 20.5 0.0 0.00057 20.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin I-set PF07679.16 KFP03509.1 - 3.1e-15 56.0 0.0 1.5e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP03509.1 - 4e-14 53.0 1.5 3.7e-07 30.6 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFP03509.1 - 4e-09 36.4 1.1 3.4e-05 23.8 0.1 2.4 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 KFP03509.1 - 9.2e-09 35.5 0.6 8e-05 22.9 0.1 2.6 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP03509.1 - 1.6e-08 34.6 3.9 0.0013 18.8 0.2 2.7 2 1 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.15 KFP03509.1 - 0.00012 22.4 0.6 0.00069 20.0 0.0 2.4 2 1 0 2 2 2 1 Immunoglobulin C1-set domain V-set PF07686.17 KFP03509.1 - 0.00014 22.0 1.8 0.077 13.2 0.2 3.0 2 2 0 2 2 2 2 Immunoglobulin V-set domain TMEM154 PF15102.6 KFP03509.1 - 0.0046 16.9 1.2 0.0046 16.9 1.2 1.8 2 0 0 2 2 2 1 TMEM154 protein family Marek_A PF02124.15 KFP03509.1 - 0.12 12.2 5.9 0.31 10.8 5.9 1.7 1 1 0 1 1 1 0 Marek's disease glycoprotein A Protocadherin PF08374.11 KFP03509.1 - 0.26 11.2 1.9 0.49 10.3 1.9 1.5 1 0 0 1 1 1 0 Protocadherin Shisa PF13908.6 KFP03509.1 - 0.74 10.0 4.1 0.39 10.9 1.7 1.8 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator IQ PF00612.27 KFP03510.1 - 0.0093 15.7 0.5 0.013 15.2 0.5 1.2 1 0 0 1 1 1 1 IQ calmodulin-binding motif I-set PF07679.16 KFP03511.1 - 3.6e-105 344.2 5.4 6.9e-14 51.7 0.0 10.8 12 0 0 12 12 12 8 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP03511.1 - 4.1e-101 331.7 14.1 4.9e-15 55.9 0.5 10.2 10 0 0 10 10 9 8 Immunoglobulin domain Ig_2 PF13895.6 KFP03511.1 - 2.1e-76 252.3 11.0 6.6e-10 39.2 0.0 9.4 9 0 0 9 9 9 8 Immunoglobulin domain fn3 PF00041.21 KFP03511.1 - 2.2e-70 233.0 12.7 7.1e-14 51.9 0.0 8.0 8 0 0 8 8 7 6 Fibronectin type III domain ig PF00047.25 KFP03511.1 - 4.7e-66 219.0 6.0 8.2e-09 35.5 0.0 9.5 9 0 0 9 9 9 8 Immunoglobulin domain V-set PF07686.17 KFP03511.1 - 6.5e-27 93.9 26.1 0.0016 18.6 0.1 13.4 9 6 0 9 9 8 7 Immunoglobulin V-set domain Ig_5 PF16681.5 KFP03511.1 - 2.8e-21 75.7 0.0 0.078 13.4 0.0 8.8 8 1 0 8 8 8 4 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KFP03511.1 - 3.1e-15 56.0 4.1 2 8.6 0.1 8.8 8 0 0 8 8 8 5 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFP03511.1 - 2.1e-13 49.6 0.1 0.59 9.7 0.0 6.8 7 0 0 7 7 7 4 Immunoglobulin domain Ig_4 PF16680.5 KFP03511.1 - 6.7e-12 45.5 1.1 1.4 9.3 0.0 8.3 7 2 0 7 7 7 2 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 KFP03511.1 - 5e-09 36.4 5.1 0.026 14.9 0.0 7.3 9 0 0 9 9 6 1 Immunoglobulin C1-set domain Interfer-bind PF09294.10 KFP03511.1 - 1.9e-07 31.3 0.3 0.1 12.9 0.0 4.9 5 0 0 5 5 5 2 Interferon-alpha/beta receptor, fibronectin type III Izumo-Ig PF16706.5 KFP03511.1 - 3.4e-07 30.2 0.6 23 5.1 0.0 7.0 7 0 0 7 7 7 0 Izumo-like Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFP03511.1 - 2.2e-06 28.1 10.9 1.2 9.7 0.0 7.6 6 2 0 6 6 6 2 Purple acid Phosphatase, N-terminal domain Ig_C17orf99 PF17736.1 KFP03511.1 - 2.4e-06 27.5 0.0 0.93 9.6 0.0 6.0 6 0 0 6 6 6 1 C17orf99 Ig domain Receptor_2B4 PF11465.8 KFP03511.1 - 4.4e-06 26.9 0.2 3.9 7.7 0.0 5.3 5 0 0 5 5 4 2 Natural killer cell receptor 2B4 ChitinaseA_N PF08329.10 KFP03511.1 - 7.7e-06 25.6 0.0 0.0046 16.6 0.0 3.1 2 0 0 2 2 2 1 Chitinase A, N-terminal domain V-set_CD47 PF08204.11 KFP03511.1 - 0.00015 21.8 0.7 1.7 8.6 0.0 5.8 7 0 0 7 7 7 1 CD47 immunoglobulin-like domain EphA2_TM PF14575.6 KFP03511.1 - 0.13 13.2 0.1 0.29 12.1 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR1 PF02440.15 KFP03511.1 - 0.18 11.6 0.0 0.18 11.6 0.0 4.2 6 0 0 6 6 4 0 Adenovirus E3 region protein CR1 DUF4446 PF14584.6 KFP03511.1 - 0.45 10.5 2.3 0.76 9.8 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Ig_2 PF13895.6 KFP03512.1 - 9.3e-06 25.9 0.0 4.2e-05 23.8 0.0 2.0 2 1 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 KFP03512.1 - 0.00026 21.5 0.0 0.0024 18.4 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Asp PF00026.23 KFP03513.1 - 1e-39 136.8 0.1 2e-39 135.9 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KFP03513.1 - 6.5e-13 48.8 0.0 9.5e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 KFP03513.1 - 0.00046 20.5 0.1 0.0019 18.5 0.1 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal ILEI PF15711.5 KFP03514.1 - 3.2e-18 66.0 0.0 5.3e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Interleukin-like EMT inducer Dynamin_M PF01031.20 KFP03515.1 - 3.6e-70 236.4 11.6 5e-70 235.9 11.6 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KFP03515.1 - 3.1e-43 147.7 0.5 1.2e-42 145.8 0.0 2.2 3 0 0 3 3 3 1 Dynamin family GED PF02212.18 KFP03515.1 - 9.2e-14 51.4 0.2 6.5e-13 48.6 0.1 2.6 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KFP03515.1 - 1.1e-05 25.5 0.1 5.2e-05 23.3 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KFP03515.1 - 0.006 17.1 0.0 0.022 15.3 0.0 1.9 1 0 0 1 1 1 1 ABC transporter AAA_15 PF13175.6 KFP03515.1 - 0.013 15.3 0.1 0.013 15.3 0.1 3.0 2 1 1 3 3 3 0 AAA ATPase domain AAA_29 PF13555.6 KFP03515.1 - 0.014 15.2 0.1 0.029 14.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KFP03515.1 - 0.043 14.2 4.9 0.13 12.6 0.0 3.0 3 1 0 3 3 3 0 AAA ATPase domain AAA_21 PF13304.6 KFP03515.1 - 0.053 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system FeoB_N PF02421.18 KFP03515.1 - 0.11 12.1 0.1 0.69 9.4 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Trypsin PF00089.26 KFP03516.1 - 4.2e-53 180.4 0.2 6.8e-53 179.7 0.2 1.3 1 0 0 1 1 1 1 Trypsin SRCR_2 PF15494.6 KFP03516.1 - 4.7e-30 104.0 0.0 1.1e-29 102.8 0.0 1.7 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFP03516.1 - 5.4e-10 39.8 0.2 1.7e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 Hepsin, SRCR domain DUF1986 PF09342.11 KFP03516.1 - 5.3e-08 33.3 0.1 1.2e-07 32.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Ldl_recept_a PF00057.18 KFP03516.1 - 5.7e-06 26.5 5.7 1.6e-05 25.0 5.7 1.8 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A SRCR PF00530.18 KFP03516.1 - 8e-06 26.3 0.0 2.1e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Trypsin_2 PF13365.6 KFP03516.1 - 0.003 18.4 0.0 0.018 16.0 0.0 2.1 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF3149 PF11346.8 KFP03516.1 - 6.3 6.5 6.2 15 5.3 6.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) zf-C2H2 PF00096.26 KFP03517.1 - 9e-47 155.0 141.3 7.7e-06 26.1 1.1 17.8 18 0 0 18 18 17 16 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP03517.1 - 7.6e-44 144.6 130.0 0.00056 20.5 0.5 18.0 18 0 0 18 18 18 16 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP03517.1 - 7e-30 102.1 113.7 1.4e-05 25.3 0.5 17.4 18 0 0 18 18 17 10 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFP03517.1 - 1.1e-20 73.4 95.4 0.0065 16.7 0.8 17.7 18 0 0 18 18 18 9 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP03517.1 - 4.9e-14 52.2 106.7 0.078 13.4 2.3 16.9 18 0 0 18 18 17 11 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFP03517.1 - 2.4e-05 24.2 106.6 0.27 11.3 0.0 16.8 17 0 0 17 17 17 6 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFP03517.1 - 0.00031 20.6 50.4 0.021 14.7 0.2 10.9 11 0 0 11 11 11 4 zinc-finger of a C2HC-type SET PF00856.28 KFP03517.1 - 0.00078 19.9 0.1 0.011 16.2 0.0 2.7 3 0 0 3 3 2 1 SET domain zf_PR_Knuckle PF18445.1 KFP03517.1 - 0.0019 18.0 0.7 0.0019 18.0 0.7 4.1 3 0 0 3 3 3 1 PR zinc knuckle motif zf-MYST PF17772.1 KFP03517.1 - 0.015 14.9 0.9 0.015 14.9 0.9 10.1 10 2 2 12 12 12 0 MYST family zinc finger domain BolA PF01722.18 KFP03517.1 - 0.14 12.5 15.3 54 4.2 0.2 7.3 5 2 3 8 8 8 0 BolA-like protein zinc_ribbon_15 PF17032.5 KFP03517.1 - 2.9 8.7 75.0 2 9.2 0.8 9.6 7 2 2 10 10 9 0 zinc-ribbon family SMP_C2CD2L PF18696.1 KFP03518.1 - 3.3e-43 147.2 3.8 3.3e-43 147.2 3.8 1.9 2 0 0 2 2 2 1 Synaptotagmin-like, mitochondrial and lipid-binding domain C2 PF00168.30 KFP03518.1 - 2.1e-08 34.4 0.1 1.2e-07 32.0 0.0 2.3 2 0 0 2 2 2 1 C2 domain CEP76-C2 PF15627.6 KFP03518.1 - 0.065 12.8 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 CEP76 C2 domain BTB PF00651.31 KFP03519.1 - 7.2e-26 90.6 0.1 1.4e-25 89.7 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf_C2H2_6 PF18450.1 KFP03519.1 - 1.9e-17 62.6 5.9 1.9e-17 62.6 5.9 3.6 3 0 0 3 3 3 1 Zinc Finger domain zf-C2H2 PF00096.26 KFP03519.1 - 1.3e-14 53.8 69.8 0.001 19.4 1.6 9.4 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP03519.1 - 2.2e-14 52.9 73.2 0.016 16.0 0.9 9.6 9 0 0 9 9 9 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP03519.1 - 0.0063 16.9 4.7 0.0063 16.9 4.7 10.8 11 1 0 11 11 11 3 Zinc-finger double domain zf-met PF12874.7 KFP03519.1 - 0.018 15.4 40.1 0.042 14.2 2.4 7.6 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KFP03519.1 - 0.1 13.1 0.0 0.1 13.1 0.0 6.5 5 2 1 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger zf-MYST PF17772.1 KFP03519.1 - 0.29 10.8 0.0 0.29 10.8 0.0 6.2 7 1 1 8 8 8 0 MYST family zinc finger domain zf-C2H2_6 PF13912.6 KFP03519.1 - 0.39 10.8 52.9 0.51 10.4 0.5 8.3 9 0 0 9 9 9 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP03519.1 - 3.7 7.9 50.6 0.14 12.5 2.3 9.0 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFP03519.1 - 6.9 6.5 26.7 1.6 8.6 0.4 6.1 6 0 0 6 6 6 0 zinc-finger C2H2-type Zona_pellucida PF00100.23 KFP03520.1 - 1.4e-40 139.8 4.9 1.4e-40 139.8 4.9 2.5 2 1 1 3 3 3 1 Zona pellucida-like domain EGF_CA PF07645.15 KFP03520.1 - 4.2e-17 62.1 42.3 6.3e-08 32.7 6.9 4.7 4 0 0 4 4 4 3 Calcium-binding EGF domain SEA PF01390.20 KFP03520.1 - 8.1e-13 48.4 8.4 1.5e-07 31.5 0.4 3.4 4 0 0 4 4 4 2 SEA domain WAP PF00095.21 KFP03520.1 - 7.5e-07 29.4 9.0 7.5e-07 29.4 9.0 3.7 4 0 0 4 4 3 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' EGF_3 PF12947.7 KFP03520.1 - 1.5e-05 25.1 6.7 1.5e-05 25.1 6.7 4.0 4 0 0 4 4 3 2 EGF domain fn3 PF00041.21 KFP03520.1 - 0.087 13.2 0.1 0.37 11.2 0.1 2.1 2 0 0 2 2 1 0 Fibronectin type III domain Arylsulfotran_N PF17425.2 KFP03520.1 - 0.12 12.4 0.1 0.33 11.0 0.1 1.8 1 0 0 1 1 1 0 Arylsulfotransferase Ig-like domain EMI PF07546.13 KFP03520.1 - 0.28 12.0 14.8 0.021 15.6 8.3 2.7 2 0 0 2 2 1 0 EMI domain EGF PF00008.27 KFP03520.1 - 1 9.7 29.2 0.024 15.0 6.1 4.1 4 0 0 4 4 4 0 EGF-like domain Plasmod_Pvs28 PF06247.11 KFP03520.1 - 4.1 7.8 21.9 1.4 9.3 3.9 4.0 3 0 0 3 3 3 0 Pvs28 EGF domain hEGF PF12661.7 KFP03520.1 - 9.1 7.1 28.7 0.093 13.4 4.5 4.4 4 0 0 4 4 3 0 Human growth factor-like EGF ABC2_membrane PF01061.24 KFP03521.1 - 1.1e-46 159.0 25.7 1.1e-46 159.0 25.7 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KFP03521.1 - 6.3e-30 104.5 0.0 1e-29 103.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFP03521.1 - 3.4e-07 30.4 0.0 0.0037 17.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFP03521.1 - 4.3e-07 29.6 0.0 1.5e-06 27.8 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KFP03521.1 - 0.00012 22.0 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_13 PF13166.6 KFP03521.1 - 0.0056 15.4 0.0 0.087 11.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFP03521.1 - 0.007 16.1 0.6 0.016 14.9 0.6 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KFP03521.1 - 0.0074 16.7 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 KFP03521.1 - 0.013 15.6 0.1 0.024 14.7 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 KFP03521.1 - 0.029 14.9 0.3 0.048 14.1 0.3 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFP03521.1 - 0.047 14.2 0.0 0.095 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFP03521.1 - 0.052 13.8 0.1 0.16 12.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFP03521.1 - 0.068 13.4 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFP03521.1 - 0.072 12.8 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KFP03521.1 - 0.092 12.7 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Cytidylate_kin PF02224.18 KFP03521.1 - 0.19 11.4 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase DUF1440 PF07274.12 KFP03521.1 - 0.31 11.4 4.4 3.8 7.9 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1440) Trefoil PF00088.18 KFP03522.1 - 9.3e-27 92.7 26.4 2.1e-14 53.1 9.3 2.2 2 0 0 2 2 2 2 Trefoil (P-type) domain Trypsin PF00089.26 KFP03523.1 - 3.8e-73 245.9 0.4 5.3e-73 245.5 0.4 1.2 1 0 0 1 1 1 1 Trypsin SRCR_2 PF15494.6 KFP03523.1 - 1.6e-25 89.5 1.2 3.2e-25 88.5 1.2 1.5 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFP03523.1 - 4.9e-10 39.9 1.0 1.2e-09 38.6 1.0 1.6 1 0 0 1 1 1 1 Hepsin, SRCR domain DUF1986 PF09342.11 KFP03523.1 - 9.3e-07 29.2 0.1 2.1e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) SRCR PF00530.18 KFP03523.1 - 1.5e-06 28.7 0.2 1.5e-06 28.7 0.2 2.0 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Ldl_recept_a PF00057.18 KFP03523.1 - 6.9e-06 26.2 8.0 2.3e-05 24.5 8.0 1.9 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Trypsin_2 PF13365.6 KFP03523.1 - 3.3e-05 24.8 0.0 6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain His_Phos_1 PF00300.22 KFP03524.1 - 4.7e-17 62.3 0.0 1.2e-16 60.9 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SH3_9 PF14604.6 KFP03524.1 - 3.4e-13 49.2 0.0 6.4e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP03524.1 - 0.00026 20.6 0.0 0.00068 19.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP03524.1 - 0.00031 20.3 0.0 0.00065 19.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain UBA PF00627.31 KFP03524.1 - 0.044 13.7 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain 2_5_RNA_ligase2 PF13563.6 KFP03524.1 - 0.13 12.2 0.4 0.83 9.5 0.4 2.1 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KFP03524.1 - 0.15 12.2 0.1 31 4.9 0.0 2.8 2 0 0 2 2 2 0 LigT like Phosphoesterase MORN PF02493.20 KFP03525.1 - 4.4e-36 120.6 43.4 1.9e-10 40.0 1.9 7.3 7 0 0 7 7 7 7 MORN repeat DUF1579 PF07617.11 KFP03525.1 - 0.081 12.8 2.5 0.43 10.5 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1579) MFS_1 PF07690.16 KFP03526.1 - 1.4e-33 116.3 38.1 1.7e-28 99.6 28.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KFP03526.1 - 0.0088 14.4 9.7 0.017 13.4 4.2 3.0 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 KFP03526.1 - 0.042 12.7 16.0 0.056 12.3 8.6 2.6 2 1 0 2 2 2 0 MFS_1 like family DUF2985 PF11204.8 KFP03526.1 - 0.06 13.5 2.9 3.8 7.7 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2985) PDEase_I PF00233.19 KFP03527.1 - 3.7e-87 292.0 4.1 3.7e-87 292.0 4.1 2.0 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase 4HB_MCP_1 PF12729.7 KFP03527.1 - 0.08 12.5 0.2 0.2 11.2 0.2 1.6 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction TRAF_BIRC3_bd PF16673.5 KFP03528.1 - 3.9e-21 74.6 2.0 8.4e-21 73.5 2.0 1.5 1 0 0 1 1 1 1 TNF receptor-associated factor BIRC3 binding domain zf-TRAF PF02176.18 KFP03528.1 - 9.3e-05 23.0 7.0 9.3e-05 23.0 7.0 3.4 3 0 0 3 3 3 2 TRAF-type zinc finger zf-C3HC4 PF00097.25 KFP03528.1 - 0.00024 20.9 10.4 0.00024 20.9 10.4 3.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP03528.1 - 0.0031 17.5 2.5 0.0031 17.5 2.5 3.6 3 1 0 3 3 3 1 RING-type zinc-finger Cast PF10174.9 KFP03528.1 - 0.052 11.8 0.8 0.071 11.3 0.8 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF641 PF04859.12 KFP03528.1 - 0.18 12.1 0.8 3.3 8.1 0.8 2.3 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) zf_UBZ PF18439.1 KFP03528.1 - 1.6 8.4 7.8 15 5.3 0.3 3.8 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger PHD PF00628.29 KFP03529.1 - 6.5e-15 54.8 16.8 1.2e-09 37.9 1.3 2.5 2 0 0 2 2 2 2 PHD-finger Tudor_2 PF18104.1 KFP03529.1 - 3.2e-14 52.3 0.2 7.2e-14 51.2 0.2 1.6 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain PHD_2 PF13831.6 KFP03529.1 - 0.00015 21.3 2.8 0.00015 21.3 2.8 3.6 3 2 0 3 3 3 1 PHD-finger Prok-RING_1 PF14446.6 KFP03529.1 - 0.0015 18.4 1.7 0.0015 18.4 1.7 3.3 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 DUF4537 PF15057.6 KFP03529.1 - 0.0023 17.9 0.0 0.0037 17.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) C1_1 PF00130.22 KFP03529.1 - 0.016 15.1 0.6 0.016 15.1 0.6 3.9 3 1 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) LBR_tudor PF09465.10 KFP03529.1 - 0.14 12.0 0.3 0.25 11.2 0.3 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Mtf2_C PF14061.6 KFP03530.1 - 3.6e-27 94.3 0.1 5.3e-27 93.7 0.1 1.3 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 Chromo PF00385.24 KFP03530.1 - 0.16 11.9 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain CutA1 PF03091.15 KFP03531.1 - 8.4e-32 109.0 0.0 1e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein Proteasom_PSMB PF10508.9 KFP03532.1 - 1.1e-176 588.2 0.0 1.2e-176 588.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit RICTOR_V PF14668.6 KFP03532.1 - 4.8e-05 23.5 0.6 3.1 8.1 0.0 4.1 4 0 0 4 4 4 2 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_2 PF13646.6 KFP03532.1 - 6.5e-05 23.2 0.1 0.046 14.1 0.0 4.1 3 3 2 5 5 5 1 HEAT repeats V-ATPase_H_C PF11698.8 KFP03532.1 - 0.01 15.9 0.1 6 7.0 0.0 3.4 3 0 0 3 3 3 0 V-ATPase subunit H STAG PF08514.11 KFP03532.1 - 0.053 13.4 0.0 0.37 10.7 0.0 2.3 2 0 0 2 2 2 0 STAG domain Neurochondrin PF05536.11 KFP03532.1 - 0.062 11.7 0.6 1.9 6.7 0.2 2.6 1 1 1 2 2 2 0 Neurochondrin Galactosyl_T PF01762.21 KFP03533.1 - 5.2e-36 124.3 0.0 6.5e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 KFP03533.1 - 0.094 12.1 0.0 0.17 11.3 0.0 1.5 1 1 0 1 1 1 0 Fringe-like CAMSAP_CH PF11971.8 KFP03534.1 - 7.4e-35 118.7 0.3 1.8e-34 117.4 0.3 1.7 1 0 0 1 1 1 1 CAMSAP CH domain CAMSAP_CC1 PF17095.5 KFP03534.1 - 7.7e-24 83.3 5.4 7.7e-24 83.3 5.4 3.0 2 1 0 2 2 2 1 Spectrin-binding region of Ca2+-Calmodulin CAMSAP_CKK PF08683.11 KFP03534.1 - 1.4e-12 47.8 0.0 2.7e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated CH PF00307.31 KFP03534.1 - 0.1 12.8 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 Calponin homology (CH) domain UBA PF00627.31 KFP03535.1 - 3.9e-17 61.8 1.0 1.4e-07 31.3 0.0 2.4 2 0 0 2 2 2 2 UBA/TS-N domain STI1 PF17830.1 KFP03535.1 - 0.0039 17.1 0.3 0.013 15.4 0.3 2.0 1 0 0 1 1 1 1 STI1 domain UBA_3 PF09288.10 KFP03535.1 - 0.0068 16.2 0.1 1.3 8.9 0.0 3.0 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain UBA_2 PF08587.11 KFP03535.1 - 0.018 15.2 0.0 0.056 13.6 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) BTB PF00651.31 KFP03536.1 - 1.2e-23 83.4 0.0 2.3e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BEN PF10523.9 KFP03536.1 - 4.7e-10 39.6 0.1 1.2e-09 38.3 0.1 1.7 1 0 0 1 1 1 1 BEN domain LIM PF00412.22 KFP03537.1 - 1.8e-14 53.7 8.2 2.6e-14 53.2 8.2 1.3 1 0 0 1 1 1 1 LIM domain Homeodomain PF00046.29 KFP03537.1 - 5.9e-14 51.6 0.3 1.1e-13 50.8 0.3 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP03537.1 - 0.00033 20.5 0.0 0.00099 19.0 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain Furin-like_2 PF15913.5 KFP03537.1 - 0.0022 18.1 1.0 0.0044 17.2 1.0 1.4 1 0 0 1 1 1 1 Furin-like repeat, cysteine-rich DUF4449 PF14613.6 KFP03537.1 - 0.11 12.6 0.1 0.17 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) QSOX_Trx1 PF18108.1 KFP03538.1 - 1.8e-42 143.9 0.0 3.8e-42 142.8 0.0 1.6 1 0 0 1 1 1 1 QSOX Trx-like domain FAD_SOX PF18371.1 KFP03538.1 - 2.8e-31 107.9 0.2 3.3e-30 104.5 0.0 3.0 2 1 0 2 2 2 1 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Evr1_Alr PF04777.13 KFP03538.1 - 1.4e-26 92.9 1.1 3.3e-26 91.7 0.4 2.1 2 0 0 2 2 2 1 Erv1 / Alr family Thioredoxin PF00085.20 KFP03538.1 - 0.074 13.1 0.0 0.56 10.2 0.0 2.4 3 0 0 3 3 3 0 Thioredoxin Zn-ribbon_8 PF09723.10 KFP03538.1 - 0.21 11.7 2.4 8.1 6.6 0.2 2.7 2 0 0 2 2 2 0 Zinc ribbon domain zf-C3HC4_3 PF13920.6 KFP03538.1 - 0.51 10.2 1.8 12 5.8 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-HYPF PF07503.12 KFP03538.1 - 1.1 9.0 2.9 25 4.8 0.2 2.6 2 0 0 2 2 2 0 HypF finger FlhE PF06366.13 KFP03540.1 - 0.093 12.7 0.5 0.14 12.2 0.4 1.6 1 1 0 1 1 1 0 Flagellar protein FlhE CRISPR_Cas9_WED PF18061.1 KFP03540.1 - 0.1 12.7 0.9 0.13 12.3 0.9 1.2 1 0 0 1 1 1 0 CRISPR-Cas9 WED domain GoLoco PF02188.17 KFP03541.1 - 6.6e-41 137.3 25.7 9.3e-11 41.0 2.1 4.4 4 0 0 4 4 4 4 GoLoco motif TPR_12 PF13424.6 KFP03541.1 - 4.1e-40 135.9 28.6 1e-09 38.5 1.9 6.0 4 2 2 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 KFP03541.1 - 2.1e-35 119.1 30.9 1.9e-05 24.3 0.6 8.8 10 0 0 10 10 8 7 Tetratricopeptide repeat TPR_7 PF13176.6 KFP03541.1 - 1.1e-30 103.4 18.3 3.4e-06 26.7 0.2 9.0 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 KFP03541.1 - 2.1e-21 74.3 25.0 0.0031 17.6 0.5 8.8 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 KFP03541.1 - 5.7e-20 69.8 28.9 0.012 15.7 0.0 9.1 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_10 PF13374.6 KFP03541.1 - 9.3e-20 69.9 18.2 0.00048 19.9 0.0 8.4 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.6 KFP03541.1 - 8.5e-07 29.3 4.5 29 5.8 0.0 7.7 4 3 4 8 8 8 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP03541.1 - 1.3e-06 28.1 8.3 0.033 13.6 2.8 3.1 2 1 1 3 3 3 3 MalT-like TPR region Rapsyn_N PF10579.9 KFP03541.1 - 1.3e-05 25.1 1.5 0.84 9.8 0.1 4.6 3 2 2 5 5 5 2 Rapsyn N-terminal myristoylation and linker region TPR_4 PF07721.14 KFP03541.1 - 2.6e-05 24.4 5.3 17 6.4 0.0 6.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFP03541.1 - 9.1e-05 22.1 22.0 0.16 11.7 0.2 7.7 7 2 0 7 7 6 1 TPR repeat TPR_16 PF13432.6 KFP03541.1 - 0.00014 22.4 12.9 0.15 12.7 0.0 7.3 4 2 1 7 7 7 1 Tetratricopeptide repeat UreE_C PF05194.12 KFP03541.1 - 0.064 13.8 0.9 6.8 7.3 0.1 3.0 2 1 1 3 3 2 0 UreE urease accessory protein, C-terminal domain DUF4807 PF16065.5 KFP03541.1 - 0.1 12.3 0.1 22 4.7 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4807) ANAPC5 PF12862.7 KFP03541.1 - 0.19 11.8 1.0 30 4.8 0.0 3.9 2 1 3 5 5 5 0 Anaphase-promoting complex subunit 5 TPR_15 PF13429.6 KFP03541.1 - 0.28 10.4 3.6 13 4.9 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat FliJ PF02050.16 KFP03541.1 - 0.28 11.4 3.6 0.89 9.8 0.2 3.1 2 2 1 3 3 3 0 Flagellar FliJ protein TPR_17 PF13431.6 KFP03541.1 - 0.69 10.4 15.7 21 5.8 0.0 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFP03541.1 - 2.3 9.0 9.8 1.8e+02 3.1 0.1 6.7 8 1 0 8 8 8 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP03541.1 - 3.2 8.0 14.2 35 4.7 0.0 4.7 4 2 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-DNL PF05180.12 KFP03542.1 - 1.1e-26 92.5 0.1 1.4e-26 92.2 0.1 1.1 1 0 0 1 1 1 1 DNL zinc finger Rib PF08428.10 KFP03542.1 - 0.1 12.6 1.1 2.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Rib/alpha-like repeat CARD PF00619.21 KFP03543.1 - 1.6e-21 76.1 0.0 1.6e-21 76.1 0.0 2.5 3 0 0 3 3 3 1 Caspase recruitment domain CARD_2 PF16739.5 KFP03543.1 - 8.5e-06 25.7 0.2 5.1e-05 23.2 0.0 2.6 2 0 0 2 2 2 1 Caspase recruitment domain Myb_DNA-binding PF00249.31 KFP03544.1 - 2.4e-56 187.7 17.7 1.3e-15 57.3 1.2 5.7 5 0 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFP03544.1 - 1.1e-40 137.6 14.1 1.5e-13 50.8 0.1 5.7 1 1 4 5 5 5 5 Myb-like DNA-binding domain SLIDE PF09111.10 KFP03544.1 - 1.6e-07 31.3 19.9 0.019 15.0 0.0 5.6 4 1 2 7 7 7 3 SLIDE Myb_DNA-bind_2 PF08914.11 KFP03544.1 - 0.0034 17.5 0.3 1.2 9.3 0.1 3.2 2 1 0 2 2 2 1 Rap1 Myb domain SANT_DAMP1_like PF16282.5 KFP03544.1 - 0.013 15.7 10.5 0.59 10.4 0.6 4.4 2 2 2 4 4 4 0 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 KFP03544.1 - 0.022 14.8 0.0 0.58 10.3 0.0 3.2 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF5320 PF17253.2 KFP03544.1 - 0.34 12.0 3.5 0.79 10.8 1.7 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5320) MerR-DNA-bind PF09278.11 KFP03544.1 - 0.62 10.6 4.4 12 6.5 0.6 3.0 2 0 0 2 2 2 0 MerR, DNA binding Myb_DNA-bind_5 PF13873.6 KFP03544.1 - 1.2 9.3 12.5 16 5.6 0.1 5.3 5 1 0 5 5 5 0 Myb/SANT-like DNA-binding domain VGPC1_C PF16799.5 KFP03544.1 - 1.6 8.8 0.0 1.6 8.8 0.0 4.1 4 1 1 5 5 5 0 C-terminal membrane-localisation domain of ion-channel, VCN1 ERM PF00769.19 KFP03545.1 - 0.015 15.1 15.6 0.018 14.9 15.6 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Monooxygenase_B PF04744.12 KFP03545.1 - 0.023 13.6 0.8 0.025 13.4 0.8 1.1 1 0 0 1 1 1 0 Monooxygenase subunit B protein AP1AR PF15745.5 KFP03545.1 - 0.041 13.5 9.1 0.053 13.1 9.1 1.2 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein LNP1 PF15419.6 KFP03545.1 - 0.076 13.2 6.3 0.13 12.5 6.3 1.4 1 1 0 1 1 1 0 Leukemia NUP98 fusion partner 1 Tropomyosin PF00261.20 KFP03545.1 - 0.082 12.3 20.4 0.15 11.4 18.1 2.3 1 1 0 1 1 1 0 Tropomyosin CENP-O PF09496.10 KFP03545.1 - 0.16 11.9 5.4 0.2 11.6 5.4 1.2 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component CLZ PF16526.5 KFP03545.1 - 0.57 10.6 15.5 0.43 11.0 9.2 3.2 1 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2514 PF10721.9 KFP03545.1 - 0.84 9.6 9.7 0.9 9.6 7.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2514) DUF724 PF05266.14 KFP03545.1 - 1 9.2 17.0 0.26 11.1 13.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 KFP03545.1 - 1.8 6.4 11.4 2 6.2 11.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EPL1 PF10513.9 KFP03545.1 - 2.1 8.7 8.7 3.1 8.1 8.7 1.3 1 1 0 1 1 1 0 Enhancer of polycomb-like TPR_MLP1_2 PF07926.12 KFP03545.1 - 2.4 8.3 26.5 1.1 9.4 22.7 1.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF5094 PF17015.5 KFP03545.1 - 6.2 6.9 15.9 8.9 6.4 13.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5094) Peptidase_M16_C PF05193.21 KFP03546.1 - 3.8e-42 144.4 0.0 6.4e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KFP03546.1 - 1.5e-40 138.6 0.0 3.4e-40 137.4 0.0 1.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF2695 PF10905.8 KFP03546.1 - 0.013 15.7 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) Exo_endo_phos PF03372.23 KFP03547.1 - 2.4e-09 37.1 0.5 2.2e-08 33.9 0.0 2.3 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family K_channel_TID PF07941.11 KFP03547.1 - 0.094 13.2 3.8 0.17 12.4 3.8 1.3 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Sec16_C PF12931.7 KFP03548.1 - 5.5e-43 147.7 0.0 1.1e-42 146.8 0.0 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KFP03548.1 - 1.4e-06 28.9 0.0 3.7e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region CadC_C1 PF18500.1 KFP03548.1 - 0.081 13.1 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 CadC C-terminal domain 1 Ank_2 PF12796.7 KFP03549.1 - 8e-38 128.9 23.4 1.5e-12 47.9 1.8 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 KFP03549.1 - 1.3e-30 104.4 8.3 1.7e-05 25.0 0.0 6.8 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KFP03549.1 - 6e-25 87.0 10.0 1.6e-10 41.0 0.2 5.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP03549.1 - 1.5e-23 80.3 1.6 0.00035 20.8 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 KFP03549.1 - 4.6e-22 78.1 9.0 5.7e-07 30.0 0.0 5.1 2 1 4 6 6 6 5 Ankyrin repeats (many copies) PUB_1 PF18486.1 KFP03549.1 - 0.069 13.0 0.5 3.3 7.6 0.1 2.6 2 0 0 2 2 2 0 PNGase/UBA- or UBX-containing domain EGF PF00008.27 KFP03550.1 - 7e-110 358.7 239.2 4e-10 39.8 8.0 15.3 15 0 0 15 15 15 15 EGF-like domain hEGF PF12661.7 KFP03550.1 - 7.5e-65 213.5 208.1 1.1e-06 29.1 7.9 17.6 17 0 0 17 17 17 15 Human growth factor-like EGF EGF_CA PF07645.15 KFP03550.1 - 6.1e-48 160.8 233.9 1.9e-07 31.2 9.5 15.2 8 3 7 15 15 15 15 Calcium-binding EGF domain EGF_2 PF07974.13 KFP03550.1 - 4.9e-19 68.4 255.6 0.0048 17.2 6.3 15.4 15 0 0 15 15 15 13 EGF-like domain EGF_3 PF12947.7 KFP03550.1 - 4.4e-10 39.6 212.2 0.0017 18.5 2.9 16.5 9 6 6 15 15 15 10 EGF domain FXa_inhibition PF14670.6 KFP03550.1 - 1.2e-08 35.1 210.2 0.4 11.0 4.0 15.7 5 3 10 15 15 15 10 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFP03550.1 - 0.0012 18.8 206.1 0.007 16.3 5.2 19.1 18 6 0 18 18 18 10 Complement Clr-like EGF-like EMI PF07546.13 KFP03551.1 - 3.8e-17 62.8 5.3 3.8e-17 62.8 5.3 2.1 2 0 0 2 2 1 1 EMI domain FXa_inhibition PF14670.6 KFP03551.1 - 3.3e-10 40.1 6.3 3.3e-10 40.1 6.3 3.2 2 1 1 3 3 3 1 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 KFP03551.1 - 3.6e-10 39.9 4.8 3.6e-10 39.9 4.8 3.2 2 1 1 3 3 3 1 Calcium-binding EGF domain cEGF PF12662.7 KFP03551.1 - 1.6e-05 24.7 0.5 1.6e-05 24.7 0.5 3.5 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF_2 PF07974.13 KFP03551.1 - 0.00085 19.6 10.0 0.00085 19.6 10.0 3.4 4 0 0 4 4 4 1 EGF-like domain EGF_3 PF12947.7 KFP03551.1 - 0.008 16.4 1.9 0.008 16.4 1.9 3.2 3 0 0 3 3 3 1 EGF domain hEGF PF12661.7 KFP03551.1 - 0.011 16.3 8.6 0.011 16.3 8.6 4.1 4 0 0 4 4 4 0 Human growth factor-like EGF EGF PF00008.27 KFP03551.1 - 0.015 15.6 8.5 0.015 15.6 8.5 3.9 4 0 0 4 4 4 0 EGF-like domain Seryl_tRNA_N PF02403.22 KFP03551.1 - 0.049 13.9 0.2 0.16 12.2 0.0 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain bZIP_2 PF07716.15 KFP03551.1 - 0.059 13.5 3.7 2.9 8.0 1.0 2.2 2 0 0 2 2 2 0 Basic region leucine zipper DUF5320 PF17253.2 KFP03551.1 - 0.089 13.9 1.0 12 7.0 0.6 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5320) DUF4988 PF16378.5 KFP03551.1 - 0.23 11.1 0.1 3.5 7.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function Uds1 PF15456.6 KFP03551.1 - 0.54 10.4 2.2 2.6 8.2 0.3 2.1 2 0 0 2 2 2 0 Up-regulated During Septation Pox_A_type_inc PF04508.12 KFP03551.1 - 4.7 7.2 9.0 0.6 10.0 1.2 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat PIP49_C PF12260.8 KFP03552.1 - 2.6e-60 203.3 0.2 2.6e-60 203.3 0.2 1.7 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 PIP49_N PF14875.6 KFP03552.1 - 8.3e-59 198.0 0.1 1.7e-58 197.0 0.0 1.6 2 0 0 2 2 2 1 N-term cysteine-rich ER, FAM69 EF-hand_1 PF00036.32 KFP03552.1 - 0.00048 19.5 0.1 0.0037 16.7 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 KFP03552.1 - 0.0034 16.8 0.2 0.031 13.8 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KFP03552.1 - 0.086 13.3 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair Ribosomal_S2 PF00318.20 KFP03553.1 - 4.4e-43 147.0 0.3 3.2e-22 78.8 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 PPP1R26_N PF15740.5 KFP03554.1 - 0 1014.8 61.7 1.6e-303 1009.8 61.7 2.0 1 1 0 1 1 1 1 Protein phosphatase 1 regulatory subunit 26 N-terminus WHEP-TRS PF00458.20 KFP03554.1 - 0.11 12.7 6.7 5.3 7.3 1.7 3.5 3 0 0 3 3 3 0 WHEP-TRS domain OLF PF02191.16 KFP03555.1 - 1.4e-88 296.7 4.6 2.2e-88 296.0 4.6 1.3 1 0 0 1 1 1 1 Olfactomedin-like domain Noelin-1 PF12308.8 KFP03555.1 - 4.5e-48 161.3 9.6 7.6e-47 157.4 5.2 2.7 3 0 0 3 3 3 1 Neurogenesis glycoprotein Helo_like_N PF17111.5 KFP03555.1 - 0.0017 17.8 0.7 0.0017 17.8 0.7 2.4 1 1 1 2 2 2 1 Fungal N-terminal domain of STAND proteins EzrA PF06160.12 KFP03555.1 - 0.0019 16.4 7.1 0.004 15.4 7.1 1.4 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA zf-C4H2 PF10146.9 KFP03555.1 - 0.0024 18.2 1.7 0.0038 17.6 1.7 1.3 1 0 0 1 1 1 1 Zinc finger-containing protein Baculo_PEP_C PF04513.12 KFP03555.1 - 0.012 15.6 2.0 0.13 12.3 0.3 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lipoprotein_7 PF01540.16 KFP03555.1 - 0.013 14.8 1.9 0.02 14.2 1.9 1.2 1 0 0 1 1 1 0 Adhesin lipoprotein GCP_C_terminal PF04130.13 KFP03555.1 - 0.016 14.7 2.3 0.028 13.9 2.3 1.3 1 0 0 1 1 1 0 Gamma tubulin complex component C-terminal AAA_13 PF13166.6 KFP03555.1 - 0.067 11.8 4.7 0.13 10.8 4.7 1.5 1 0 0 1 1 1 0 AAA domain Xpo1 PF08389.12 KFP03555.1 - 0.068 13.2 1.4 0.13 12.3 0.4 1.8 1 1 0 1 1 1 0 Exportin 1-like protein NPV_P10 PF05531.12 KFP03555.1 - 0.1 13.0 3.3 4.3 7.9 2.7 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TBCC_N PF16752.5 KFP03555.1 - 0.11 13.0 12.1 0.11 12.9 8.5 2.4 1 1 2 3 3 3 0 Tubulin-specific chaperone C N-terminal domain Exonuc_VII_L PF02601.15 KFP03555.1 - 0.11 12.1 5.6 0.18 11.4 5.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4795 PF16043.5 KFP03555.1 - 0.11 12.1 11.7 0.51 9.9 11.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Atg14 PF10186.9 KFP03555.1 - 0.12 11.4 9.2 0.22 10.6 9.2 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG17 PF04108.12 KFP03555.1 - 0.17 11.0 10.5 0.39 9.8 10.6 1.4 1 1 0 1 1 1 0 Autophagy protein Apg17 DUF1664 PF07889.12 KFP03555.1 - 0.23 11.5 9.2 2.6 8.1 4.4 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.6 KFP03555.1 - 0.33 11.4 10.6 10 6.6 9.4 2.6 1 1 0 1 1 1 0 Syntaxin-like protein FUSC PF04632.12 KFP03555.1 - 0.45 9.0 3.5 0.66 8.4 3.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-Q PF13094.6 KFP03555.1 - 0.47 10.6 12.8 1.2 9.4 12.8 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit PriC PF07445.12 KFP03555.1 - 0.77 9.7 12.9 0.45 10.4 6.8 2.2 2 0 0 2 2 2 0 Primosomal replication protein priC BLOC1_2 PF10046.9 KFP03555.1 - 0.86 9.9 14.8 0.19 12.1 1.3 3.6 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Csm2_III-A PF03750.13 KFP03555.1 - 0.93 10.3 8.3 5.2 7.9 4.1 2.4 1 1 1 2 2 2 0 Csm2 Type III-A MitMem_reg PF13012.6 KFP03555.1 - 1.1 9.7 4.0 5.8 7.4 4.0 2.1 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function CLZ PF16526.5 KFP03555.1 - 1.2 9.6 14.4 2.8 8.4 4.4 3.4 2 2 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Bacillus_HBL PF05791.11 KFP03555.1 - 1.2 8.9 6.9 8.3 6.2 2.6 2.4 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Laminin_II PF06009.12 KFP03555.1 - 1.4 8.9 8.6 0.79 9.7 3.6 2.4 1 1 1 2 2 2 0 Laminin Domain II H-kinase_dim PF02895.14 KFP03555.1 - 1.7 9.1 7.2 43 4.6 7.2 2.7 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain ABC_tran_CTD PF16326.5 KFP03555.1 - 1.8 8.8 15.1 0.58 10.4 2.6 3.7 1 1 3 4 4 4 0 ABC transporter C-terminal domain Fib_alpha PF08702.10 KFP03555.1 - 5.4 7.2 11.3 2.2 8.5 5.4 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2203 PF09969.9 KFP03555.1 - 5.4 7.8 10.8 4.1 8.2 0.9 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Latarcin PF10279.9 KFP03555.1 - 6.9 7.2 8.4 3.2 8.2 2.0 2.3 2 0 0 2 2 2 0 Latarcin precursor Spectrin PF00435.21 KFP03555.1 - 7 7.2 12.5 18 5.9 0.5 2.9 2 1 1 3 3 2 0 Spectrin repeat FapA PF03961.13 KFP03555.1 - 7.1 5.1 10.9 1.8 7.1 5.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Occludin_ELL PF07303.13 KFP03555.1 - 7.4 7.4 13.4 27 5.6 6.4 2.6 1 1 1 2 2 2 0 Occludin homology domain DASH_Dad3 PF08656.10 KFP03555.1 - 8 6.6 10.5 7.7 6.7 0.4 3.8 2 1 2 4 4 3 0 DASH complex subunit Dad3 PCRF PF03462.18 KFP03555.1 - 8.4 6.2 12.9 2.5 7.9 5.3 2.2 1 1 1 2 2 2 0 PCRF domain Collagen PF01391.18 KFP03556.1 - 6.2e-164 531.9 679.8 1.2e-09 37.7 23.8 22.1 4 2 13 17 17 17 13 Collagen triple helix repeat (20 copies) COLFI PF01410.18 KFP03556.1 - 1.3e-96 322.5 0.0 1.8e-96 322.0 0.0 1.2 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Laminin_G_2 PF02210.24 KFP03556.1 - 7.1e-05 23.4 0.0 0.00012 22.7 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.6 KFP03556.1 - 0.0028 17.8 0.0 0.0049 17.0 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_1 PF00054.23 KFP03556.1 - 0.047 13.9 0.0 0.09 13.0 0.0 1.3 1 0 0 1 1 1 0 Laminin G domain Hormone_recep PF00104.30 KFP03557.1 - 4.2e-40 137.6 0.0 7.1e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Nuc_recep-AF1 PF11825.8 KFP03557.1 - 2.8e-38 130.5 23.7 4.3e-38 129.9 23.7 1.3 1 0 0 1 1 1 1 Nuclear/hormone receptor activator site AF-1 zf-C4 PF00105.18 KFP03557.1 - 4.1e-32 110.5 16.3 6.8e-32 109.7 16.3 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Yae1_N PF09811.9 KFP03558.1 - 3.6e-11 42.6 38.0 0.015 14.9 3.6 4.0 1 1 1 2 2 2 2 Essential protein Yae1, N terminal WD40 PF00400.32 KFP03559.1 - 1.1e-62 206.4 19.9 5e-10 39.8 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP03559.1 - 4.2e-27 94.3 2.0 4.1e-05 23.8 0.1 6.2 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP03559.1 - 8.7e-15 54.3 4.7 0.0017 17.1 0.1 4.8 1 1 4 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.11 KFP03559.1 - 2.6e-12 47.0 0.1 3.1e-06 27.2 0.0 3.7 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFP03559.1 - 1.5e-06 27.5 5.1 0.026 13.5 0.8 4.1 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFP03559.1 - 1.5e-06 27.8 0.1 0.0091 15.3 0.0 3.3 1 1 3 4 4 4 3 WD40-like domain PALB2_WD40 PF16756.5 KFP03559.1 - 6.5e-06 25.3 1.9 2.1 7.2 0.0 4.2 1 1 2 4 4 4 3 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 KFP03559.1 - 0.00034 19.1 0.0 0.021 13.1 0.0 2.4 1 1 2 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz VID27 PF08553.10 KFP03559.1 - 0.0077 15.3 0.0 0.11 11.5 0.0 2.6 2 1 1 4 4 4 2 VID27 C-terminal WD40-like domain Hira PF07569.11 KFP03559.1 - 0.018 14.7 1.9 28 4.4 0.0 4.4 3 1 1 4 4 4 0 TUP1-like enhancer of split CDtoxinA PF03498.14 KFP03559.1 - 0.039 13.5 1.2 0.26 10.9 0.1 2.5 1 1 0 2 2 2 0 Cytolethal distending toxin A/C domain SBD PF17882.1 KFP03559.1 - 0.11 12.3 0.1 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 OAA-family lectin sugar binding domain Nucleoporin_N PF08801.11 KFP03559.1 - 0.14 10.8 5.3 0.32 9.7 1.7 3.0 1 1 1 2 2 2 0 Nup133 N terminal like Bromodomain PF00439.25 KFP03560.1 - 4.8e-42 141.9 5.3 2.3e-21 75.6 0.3 2.4 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KFP03560.1 - 3.5e-29 100.8 0.1 3.5e-29 100.8 0.1 2.3 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Mitofilin PF09731.9 KFP03560.1 - 5.5 5.7 40.1 10 4.8 40.1 1.4 1 0 0 1 1 1 0 Mitochondrial inner membrane protein RhoGEF PF00621.20 KFP03561.1 - 1.7e-39 135.9 7.5 1.7e-39 135.9 7.5 2.2 2 0 0 2 2 2 1 RhoGEF domain SH3_2 PF07653.17 KFP03561.1 - 5.7e-28 96.4 0.4 2.9e-14 52.5 0.1 3.7 3 0 0 3 3 3 2 Variant SH3 domain CAMSAP_CH PF11971.8 KFP03561.1 - 2.3e-24 85.0 0.3 1.2e-23 82.8 0.1 2.4 2 0 0 2 2 2 1 CAMSAP CH domain SH3_1 PF00018.28 KFP03561.1 - 1.9e-21 75.4 0.6 3.2e-12 45.9 0.1 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KFP03561.1 - 1.3e-19 69.8 0.5 2.7e-11 43.1 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain CH PF00307.31 KFP03561.1 - 1.9e-19 69.9 1.8 8.7e-19 67.7 0.0 2.8 3 0 0 3 3 3 1 Calponin homology (CH) domain SH2 PF00017.24 KFP03561.1 - 2.3e-15 56.5 0.1 8.1e-15 54.7 0.1 2.0 1 0 0 1 1 1 1 SH2 domain C1_1 PF00130.22 KFP03561.1 - 4.8e-10 39.2 2.8 1.1e-09 38.0 2.8 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 KFP03561.1 - 1.1e-08 35.5 1.9 2e-08 34.7 0.9 2.0 2 0 0 2 2 1 1 PH domain CDC24 PF06395.11 KFP03561.1 - 0.0067 16.6 0.0 0.02 15.1 0.0 1.8 1 0 0 1 1 1 1 CDC24 Calponin PH_10 PF15411.6 KFP03561.1 - 0.012 15.9 2.3 0.043 14.1 0.1 2.6 1 1 1 2 2 2 0 Pleckstrin homology domain Prok-RING_1 PF14446.6 KFP03561.1 - 0.022 14.7 2.9 0.067 13.1 2.9 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 KFP03561.1 - 0.049 13.3 0.8 0.15 11.7 0.8 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type C1_2 PF03107.16 KFP03561.1 - 0.25 11.7 8.8 0.043 14.1 4.1 2.2 2 0 0 2 2 2 0 C1 domain SH3_3 PF08239.11 KFP03561.1 - 0.31 11.3 4.5 3.4 8.0 2.2 2.8 3 0 0 3 3 3 0 Bacterial SH3 domain CotJB PF12652.7 KFP03561.1 - 1.2 9.4 6.7 1.3 9.3 0.1 3.0 3 0 0 3 3 2 0 CotJB protein GCV_T PF01571.21 KFP03562.1 - 1.3e-63 214.8 0.0 2.1e-63 214.1 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 KFP03562.1 - 1.8e-62 212.0 1.1 2.4e-62 211.6 1.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAO_M PF16350.5 KFP03562.1 - 5.1e-17 61.9 0.6 1e-16 61.0 0.6 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain GCV_T_C PF08669.11 KFP03562.1 - 4.2e-13 49.0 0.0 1e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyr_redox_2 PF07992.14 KFP03562.1 - 0.00032 20.0 0.0 0.0015 17.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFP03562.1 - 0.0051 15.9 0.1 0.01 14.9 0.1 1.5 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KFP03562.1 - 0.013 14.7 0.5 0.023 13.9 0.1 1.5 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 KFP03562.1 - 0.014 14.6 0.0 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KFP03562.1 - 0.018 14.4 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 ThiF family Pyr_redox PF00070.27 KFP03562.1 - 0.022 15.3 0.0 0.13 12.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SoxG PF04268.12 KFP03562.1 - 0.033 14.3 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 Sarcosine oxidase, gamma subunit family ApbA PF02558.16 KFP03562.1 - 0.047 13.3 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 KFP03562.1 - 0.048 12.9 2.1 0.099 11.9 0.3 2.0 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 KFP03562.1 - 0.048 13.9 0.1 0.21 11.8 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KFP03562.1 - 0.11 11.6 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Shikimate_DH PF01488.20 KFP03562.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ADAM_spacer1 PF05986.14 KFP03563.1 - 2.7e-26 91.9 0.1 4.3e-26 91.2 0.1 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.19 KFP03563.1 - 2e-22 79.1 106.5 1.4e-05 25.2 5.0 9.3 8 2 0 8 8 8 7 Thrombospondin type 1 domain PLAC PF08686.11 KFP03563.1 - 8.1e-10 39.3 9.8 4.4e-09 36.9 9.8 2.5 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain DUF3522 PF12036.8 KFP03564.1 - 6.4e-59 199.4 7.7 7.5e-59 199.2 7.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) Oxidored_q5_N PF01059.17 KFP03564.1 - 0.077 13.1 6.3 0.05 13.7 3.2 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus Sugar_tr PF00083.24 KFP03565.1 - 1.5e-85 287.8 16.0 1.8e-85 287.5 16.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP03565.1 - 1.3e-25 90.1 32.3 2.1e-25 89.4 26.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cg6151-P PF10233.9 KFP03566.1 - 1.7e-29 102.4 5.8 2.1e-29 102.1 5.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P TMEM72 PF16054.5 KFP03566.1 - 0.0088 15.8 1.1 0.011 15.5 1.1 1.2 1 0 0 1 1 1 1 Transmembrane protein family 72 DUF4191 PF13829.6 KFP03566.1 - 0.02 14.2 0.1 0.02 14.2 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) COPI_assoc PF08507.10 KFP03566.1 - 0.18 11.9 3.6 0.35 10.9 3.6 1.7 1 1 0 1 1 1 0 COPI associated protein CUB PF00431.20 KFP03567.1 - 0.0004 20.7 0.1 0.0017 18.7 0.0 1.9 2 0 0 2 2 2 1 CUB domain Reprolysin_3 PF13582.6 KFP03568.1 - 8.7e-06 26.3 0.0 9.6e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like BetaGal_dom4_5 PF13364.6 KFP03568.1 - 0.012 16.2 0.0 0.018 15.6 0.0 1.3 1 1 0 1 1 1 0 Beta-galactosidase jelly roll domain Reprolysin_4 PF13583.6 KFP03568.1 - 0.012 15.2 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 KFP03568.1 - 0.062 13.2 0.0 0.076 12.9 0.0 1.2 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease RNase_T PF00929.24 KFP03569.1 - 5.8e-20 72.5 0.0 1.1e-19 71.6 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KFP03569.1 - 0.00018 21.2 0.0 0.00058 19.6 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease Hamartin PF04388.12 KFP03569.1 - 0.88 8.2 7.6 1.3 7.6 7.6 1.1 1 0 0 1 1 1 0 Hamartin protein IFRD PF05004.13 KFP03570.1 - 0.051 12.7 1.6 2.9 6.9 0.3 2.3 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) Pkinase PF00069.25 KFP03571.1 - 1.4e-34 119.6 0.7 1.7e-34 119.4 0.7 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP03571.1 - 2.3e-26 92.6 1.7 2.5e-26 92.5 1.7 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP03571.1 - 8.8e-05 21.9 0.0 0.0001 21.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFP03571.1 - 0.024 14.0 0.1 0.027 13.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SURF4 PF02077.15 KFP03572.1 - 1.3e-122 408.6 9.5 1.4e-122 408.4 9.5 1.0 1 0 0 1 1 1 1 SURF4 family SURF2 PF05477.11 KFP03572.1 - 6e-38 130.9 0.0 6.5e-38 130.7 0.0 1.0 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) DoxX PF07681.12 KFP03572.1 - 0.11 13.2 0.2 0.11 13.2 0.2 3.5 4 1 1 5 5 5 0 DoxX DUF3043 PF11241.8 KFP03572.1 - 5.7 6.9 5.4 2 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) SURF2 PF05477.11 KFP03573.1 - 4.3e-84 281.9 2.3 4.9e-84 281.7 2.3 1.0 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) SURF1 PF02104.15 KFP03574.1 - 9.1e-44 149.8 0.0 1.1e-43 149.5 0.0 1.1 1 0 0 1 1 1 1 SURF1 family Ribosomal_L7Ae PF01248.26 KFP03575.1 - 4.9e-10 39.0 0.0 1.2e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Med22 PF06179.12 KFP03576.1 - 4.7e-37 126.4 5.1 6e-37 126.1 5.1 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex UPRTase PF14681.6 KFP03576.1 - 0.048 13.1 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DUF2746 PF10874.8 KFP03576.1 - 0.26 11.7 0.9 2.2 8.8 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2746) SURF6 PF04935.12 KFP03577.1 - 1.2e-36 126.4 66.4 1.2e-36 126.4 66.4 2.2 1 1 1 2 2 2 2 Surfeit locus protein 6 DUF4455 PF14643.6 KFP03578.1 - 9.6e-46 156.4 10.7 1.1e-45 156.3 10.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) Mannosyl_trans2 PF04188.13 KFP03578.1 - 0.029 13.7 0.2 0.032 13.6 0.2 1.0 1 0 0 1 1 1 0 Mannosyltransferase (PIG-V) NYD-SP28 PF14772.6 KFP03579.1 - 0.094 12.8 1.8 0.88 9.7 0.1 2.6 3 0 0 3 3 3 0 Sperm tail DUF4456 PF14644.6 KFP03580.1 - 1.3e-48 165.5 7.2 1.4e-48 165.3 7.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4456) Glyco_transf_6 PF03414.13 KFP03581.1 - 1.2e-138 461.3 0.0 1.4e-138 461.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 6 Glyco_tranf_2_4 PF13704.6 KFP03581.1 - 0.025 15.1 0.0 0.046 14.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Tau95 PF09734.9 KFP03582.1 - 7.5e-41 140.2 0.4 7.5e-41 140.2 0.4 2.0 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KFP03582.1 - 9.6e-30 103.4 0.1 3.9e-29 101.4 0.0 1.9 2 0 0 2 2 2 1 Tau95 Triple barrel domain FYDLN_acid PF09538.10 KFP03582.1 - 0.033 14.9 6.8 0.29 11.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) FAM176 PF14851.6 KFP03582.1 - 0.81 9.3 4.7 2.6 7.7 2.2 2.2 2 0 0 2 2 2 0 FAM176 family PTPRCAP PF15713.5 KFP03582.1 - 1 9.7 9.0 0.15 12.4 4.0 1.9 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated COesterase PF00135.28 KFP03583.1 - 2.7e-149 498.4 0.0 3.3e-149 498.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFP03583.1 - 1.8e-07 31.3 0.0 3.8e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFP03583.1 - 0.0023 17.4 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family zf-H2C2_2 PF13465.6 KFP03584.1 - 7e-30 102.1 42.8 8.9e-08 32.2 2.0 7.2 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFP03584.1 - 4.1e-29 99.4 46.0 1.1e-05 25.5 1.4 6.6 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP03584.1 - 2.4e-21 74.6 44.6 0.00031 21.3 1.2 6.7 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP03584.1 - 3.7e-15 55.8 26.5 0.003 17.8 0.0 6.9 7 0 0 7 7 6 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP03584.1 - 3.6e-10 39.6 42.4 0.0024 17.8 2.8 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger zf-met PF12874.7 KFP03584.1 - 3.3e-08 33.7 36.3 0.0075 16.6 0.3 6.8 7 0 0 7 7 7 3 Zinc-finger of C2H2 type Ta0938 PF11494.8 KFP03584.1 - 2.6e-05 24.4 0.8 0.079 13.2 0.0 2.7 2 1 1 3 3 3 2 Ta0938 zf-CHCC PF10276.9 KFP03584.1 - 0.00051 20.0 9.5 0.43 10.7 0.3 4.5 4 0 0 4 4 4 2 Zinc-finger domain zf-C2H2_3rep PF18868.1 KFP03584.1 - 0.0052 17.5 20.9 1.4 9.6 2.1 5.1 1 1 2 3 3 3 1 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 KFP03584.1 - 0.0071 16.4 22.7 1.6 8.9 1.3 5.0 3 2 2 6 6 6 3 Zinc ribbon domain zf-C2H2_8 PF15909.5 KFP03584.1 - 0.0091 16.3 20.3 0.11 12.9 1.7 3.5 1 1 3 4 4 4 2 C2H2-type zinc ribbon zf_C2H2_ZHX PF18387.1 KFP03584.1 - 0.01 15.5 3.6 0.01 15.5 3.6 3.7 3 1 2 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain FYVE PF01363.21 KFP03584.1 - 0.01 16.0 26.6 0.37 11.0 9.8 3.8 1 1 4 5 5 5 0 FYVE zinc finger zf_UBZ PF18439.1 KFP03584.1 - 0.014 15.0 19.2 6.9 6.4 0.3 5.9 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger HypA PF01155.19 KFP03584.1 - 0.028 14.4 13.3 5 7.2 6.9 3.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Prok-RING_1 PF14446.6 KFP03584.1 - 0.032 14.2 16.4 8.5 6.4 0.1 5.9 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 zf-BED PF02892.15 KFP03584.1 - 0.035 14.1 35.2 0.2 11.7 7.2 5.7 4 1 2 6 6 6 0 BED zinc finger zinc_ribbon_15 PF17032.5 KFP03584.1 - 0.051 14.3 15.2 1.2 9.9 2.0 3.5 1 1 1 3 3 3 0 zinc-ribbon family BolA PF01722.18 KFP03584.1 - 0.057 13.7 8.7 3.8 7.8 2.1 3.7 2 2 1 3 3 3 0 BolA-like protein HNH_5 PF14279.6 KFP03584.1 - 0.093 12.6 18.2 4 7.4 0.9 6.3 6 1 0 6 6 5 0 HNH endonuclease GAGA PF09237.11 KFP03584.1 - 0.17 11.7 7.7 6.9 6.6 0.1 3.9 2 2 2 4 4 4 0 GAGA factor zf-AN1 PF01428.16 KFP03584.1 - 0.19 12.0 30.9 3.5 7.9 0.2 6.9 7 0 0 7 7 7 0 AN1-like Zinc finger zf-Di19 PF05605.12 KFP03584.1 - 0.46 10.8 34.3 0.11 12.9 4.9 4.6 3 2 1 5 5 4 0 Drought induced 19 protein (Di19), zinc-binding XPA_N PF01286.18 KFP03584.1 - 0.62 10.2 21.6 7.5 6.7 0.1 6.3 6 0 0 6 6 6 0 XPA protein N-terminal zf-C2H2_11 PF16622.5 KFP03584.1 - 1.2 8.9 28.3 8 6.3 0.1 6.3 6 0 0 6 6 6 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KFP03584.1 - 1.4 9.3 30.6 2.5 8.5 0.4 6.4 2 1 4 6 6 6 0 C2H2 type zinc-finger (2 copies) PyrI_C PF02748.15 KFP03584.1 - 1.8 8.5 17.4 1.5 8.8 0.1 5.3 4 1 2 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain HalOD2 PF18547.1 KFP03584.1 - 2.3 8.2 5.7 29 4.6 0.2 3.3 3 0 0 3 3 3 0 Halobacterial output domain 2 Sprouty PF05210.13 KFP03584.1 - 2.4 8.6 12.2 3.9 7.9 0.4 2.9 2 1 0 2 2 2 0 Sprouty protein (Spry) zinc-ribbons_6 PF07191.12 KFP03584.1 - 3.5 7.7 18.8 63 3.7 2.3 4.7 1 1 2 3 3 3 0 zinc-ribbons zf-C2H2_12 PF18658.1 KFP03584.1 - 5.3 6.7 11.0 0.94 9.1 1.1 3.8 3 2 1 4 4 4 0 Zinc-finger C2H2-type ADK_lid PF05191.14 KFP03584.1 - 6.2 6.9 14.2 49 4.0 0.4 4.2 2 2 1 3 3 3 0 Adenylate kinase, active site lid Yippee-Mis18 PF03226.14 KFP03584.1 - 6.4 7.0 13.0 12 6.2 5.9 3.0 1 1 2 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C2HC_2 PF13913.6 KFP03584.1 - 8.1 6.5 28.0 1.6 8.7 1.0 5.7 6 0 0 6 6 5 0 zinc-finger of a C2HC-type HNH PF01844.23 KFP03584.1 - 9.2 6.5 25.7 1.9 8.7 0.7 5.9 7 0 0 7 7 7 0 HNH endonuclease Zf_RING PF16744.5 KFP03584.1 - 9.9 6.4 20.0 11 6.2 0.7 5.6 1 1 5 6 6 6 0 KIAA1045 RING finger SPACA9 PF15120.6 KFP03585.1 - 2e-74 248.8 0.1 2.2e-74 248.7 0.1 1.0 1 0 0 1 1 1 1 Sperm acrosome-associated protein 9 ADK PF00406.22 KFP03586.1 - 2.3e-40 138.1 0.0 2.2e-22 79.8 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 KFP03586.1 - 2.1e-19 70.3 0.0 4.3e-09 36.9 0.0 2.4 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 KFP03586.1 - 1e-13 51.7 0.0 1e-08 35.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KFP03586.1 - 2.4e-13 50.8 0.0 1.1e-09 38.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Hydin_ADK PF17213.3 KFP03586.1 - 1.3e-10 41.9 0.0 0.053 13.8 0.0 4.1 4 0 0 4 4 4 3 Hydin Adenylate kinase-like domain AAA PF00004.29 KFP03586.1 - 3.8e-09 37.1 0.1 0.0006 20.3 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFP03586.1 - 5.1e-06 27.0 0.0 0.063 13.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain KTI12 PF08433.10 KFP03586.1 - 6e-06 25.9 0.2 0.017 14.6 0.0 2.5 3 0 0 3 3 3 2 Chromatin associated protein KTI12 RuvB_N PF05496.12 KFP03586.1 - 1.9e-05 24.5 0.0 0.2 11.4 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFP03586.1 - 4e-05 23.9 0.1 0.21 11.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 KFP03586.1 - 0.00043 20.1 0.0 0.38 10.5 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 KFP03586.1 - 0.00084 18.8 0.0 0.36 10.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KFP03586.1 - 0.001 19.5 0.0 2.4 8.6 0.0 2.5 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.27 KFP03586.1 - 0.0012 19.4 0.0 1.3 9.5 0.0 2.4 2 1 0 2 2 2 2 ABC transporter ResIII PF04851.15 KFP03586.1 - 0.0015 18.6 0.0 0.04 13.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_5 PF07728.14 KFP03586.1 - 0.0021 18.0 0.1 1.9 8.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KFP03586.1 - 0.0022 17.7 0.0 0.83 9.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KFP03586.1 - 0.0023 18.2 0.0 0.69 10.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 KFP03586.1 - 0.0036 17.1 0.1 0.32 10.7 0.0 2.5 2 1 0 2 2 2 1 Cytidylate kinase Sigma54_activ_2 PF14532.6 KFP03586.1 - 0.0093 16.1 0.0 1.5 9.0 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Thymidylate_kin PF02223.17 KFP03586.1 - 0.011 15.5 0.0 4.4 6.9 0.0 3.0 3 0 0 3 3 3 0 Thymidylate kinase NACHT PF05729.12 KFP03586.1 - 0.014 15.4 0.0 0.8 9.6 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 KFP03586.1 - 0.016 14.7 0.0 5.1 6.6 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_19 PF13245.6 KFP03586.1 - 0.04 14.3 0.0 0.56 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KFP03586.1 - 0.042 13.8 0.1 8.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain Zeta_toxin PF06414.12 KFP03586.1 - 0.048 12.9 0.0 7.3 5.8 0.0 2.6 3 0 0 3 3 2 0 Zeta toxin AAA_11 PF13086.6 KFP03586.1 - 0.052 13.3 0.0 2 8.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KFP03586.1 - 0.068 12.7 0.0 5.8 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KFP03586.1 - 0.073 12.8 0.0 4.1 7.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain PMBR PF09373.10 KFP03586.1 - 0.099 12.8 0.0 9 6.7 0.0 2.6 2 0 0 2 2 2 0 Pseudomurein-binding repeat Sigma54_activat PF00158.26 KFP03586.1 - 0.12 12.0 0.0 2.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Ploopntkinase3 PF18751.1 KFP03586.1 - 0.15 12.0 0.0 15 5.4 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 ADK PF00406.22 KFP03587.1 - 0.057 13.5 0.0 0.064 13.4 0.0 1.1 1 0 0 1 1 1 0 Adenylate kinase SYS1 PF09801.9 KFP03588.1 - 3.4e-07 30.5 18.2 4.6e-07 30.1 18.2 1.2 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Trep_Strep PF09605.10 KFP03588.1 - 1.5 8.7 18.3 0.56 10.2 7.9 2.1 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Na_K-ATPase PF00287.18 KFP03588.1 - 8.6 5.4 11.2 0.21 10.7 3.7 1.8 1 1 1 2 2 2 0 Sodium / potassium ATPase beta chain Laminin_G_1 PF00054.23 KFP03589.1 - 2.8e-08 34.0 0.0 4.1e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.24 KFP03589.1 - 0.00034 21.2 0.0 0.00058 20.4 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_I PF06008.14 KFP03590.1 - 8.3e-51 173.2 15.7 9.3e-51 173.0 15.7 1.0 1 0 0 1 1 1 1 Laminin Domain I Spc7 PF08317.11 KFP03590.1 - 0.0013 17.7 11.5 0.0013 17.7 11.5 2.0 1 1 1 2 2 2 1 Spc7 kinetochore protein ADIP PF11559.8 KFP03590.1 - 0.016 15.3 11.6 0.016 15.3 11.6 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMF_TATA_bd PF12325.8 KFP03590.1 - 0.017 15.4 8.4 0.017 15.4 8.4 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CLZ PF16526.5 KFP03590.1 - 0.032 14.6 12.2 0.53 10.7 3.2 3.5 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ApoLp-III PF07464.11 KFP03590.1 - 0.044 13.9 8.1 0.12 12.5 3.7 2.9 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF3763 PF12592.8 KFP03590.1 - 0.049 13.7 0.6 18 5.5 0.0 3.5 3 1 1 4 4 3 0 Protein of unknown function (DUF3763) LPP PF04728.13 KFP03590.1 - 0.14 12.6 0.4 0.14 12.6 0.4 3.8 2 2 2 4 4 4 0 Lipoprotein leucine-zipper TIP120 PF08623.10 KFP03590.1 - 0.16 11.7 4.9 0.061 13.1 1.4 1.9 1 1 1 2 2 2 0 TATA-binding protein interacting (TIP20) DUF3829 PF12889.7 KFP03590.1 - 0.18 11.3 8.4 0.076 12.5 1.2 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3829) TPR_MLP1_2 PF07926.12 KFP03590.1 - 0.2 11.7 17.3 0.4 10.7 3.9 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Cytochrom_C_2 PF01322.20 KFP03590.1 - 0.21 12.5 6.9 0.19 12.7 0.5 2.3 1 1 1 2 2 2 0 Cytochrome C' DUF1068 PF06364.12 KFP03590.1 - 0.21 11.5 4.2 0.19 11.6 2.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1068) zf-ZPR1 PF03367.13 KFP03590.1 - 0.24 11.2 6.7 3.3 7.5 1.3 2.2 1 1 0 2 2 2 0 ZPR1 zinc-finger domain ISG65-75 PF11727.8 KFP03590.1 - 0.27 10.4 11.3 1.3 8.2 1.9 2.1 1 1 1 2 2 2 0 Invariant surface glycoprotein CK2S PF15011.6 KFP03590.1 - 0.36 10.7 10.1 1.3 8.9 1.6 2.5 1 1 1 2 2 2 0 Casein Kinase 2 substrate DUF883 PF05957.13 KFP03590.1 - 0.44 11.2 18.2 1.2 9.8 1.7 3.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF948 PF06103.11 KFP03590.1 - 0.81 10.0 10.4 5.1 7.4 2.2 3.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF334 PF03904.13 KFP03590.1 - 1.3 8.5 6.8 1.8 8.1 6.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF334) TAN PF11640.8 KFP03590.1 - 2.4 8.3 6.7 0.48 10.5 1.3 2.1 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair Prominin PF05478.11 KFP03590.1 - 2.5 6.0 7.0 3.5 5.5 7.0 1.2 1 0 0 1 1 1 0 Prominin YlqD PF11068.8 KFP03590.1 - 2.5 8.5 13.5 1.4 9.3 4.1 2.8 1 1 1 2 2 2 0 YlqD protein Spore_II_R PF09551.10 KFP03590.1 - 2.6 8.5 7.7 8.1 6.9 0.2 3.0 2 1 1 3 3 3 0 Stage II sporulation protein R (spore_II_R) HisKA_3 PF07730.13 KFP03590.1 - 3.1 8.4 14.8 8.7 6.9 0.2 4.4 1 1 3 4 4 4 0 Histidine kinase Exonuc_VII_L PF02601.15 KFP03590.1 - 3.3 7.2 17.6 1.9 8.0 7.5 2.0 1 1 1 2 2 2 0 Exonuclease VII, large subunit NACHT_N PF17100.5 KFP03590.1 - 5.3 6.8 8.8 1 9.2 0.7 2.1 1 1 1 2 2 2 0 N-terminal domain of NWD NACHT-NTPase YtxH PF12732.7 KFP03590.1 - 8.2 7.0 10.5 4e+03 -1.6 10.5 3.3 1 1 0 1 1 1 0 YtxH-like protein CENP-O PF09496.10 KFP03590.1 - 8.3 6.3 11.4 0.48 10.4 0.3 2.4 1 1 1 2 2 2 0 Cenp-O kinetochore centromere component Ribosomal_S20p PF01649.18 KFP03590.1 - 9.5 6.9 9.6 14 6.4 3.9 3.2 3 1 0 3 3 3 0 Ribosomal protein S20 Laminin_N PF00055.17 KFP03591.1 - 6.5e-73 245.2 0.0 6.5e-73 245.2 0.0 2.8 3 0 0 3 3 3 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 KFP03591.1 - 2e-50 168.7 146.0 1e-09 38.4 10.3 8.9 9 0 0 9 9 9 8 Laminin EGF domain Laminin_B PF00052.18 KFP03591.1 - 2.4e-34 118.1 0.0 3.4e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Laminin B (Domain IV) Aa_trans PF01490.18 KFP03592.1 - 1.5e-70 238.0 29.4 1.7e-70 237.9 29.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Y_phosphatase PF00102.27 KFP03593.1 - 6.4e-152 503.8 0.1 3.4e-86 288.6 0.1 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 KFP03593.1 - 6.1e-25 87.4 0.3 5.5e-10 39.5 0.0 5.1 5 0 0 5 5 5 2 Fibronectin type III domain MAM PF00629.23 KFP03593.1 - 3.2e-20 72.6 0.0 6.9e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu DSPc PF00782.20 KFP03593.1 - 2.7e-08 33.7 1.1 0.0047 16.8 0.1 2.7 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain I-set PF07679.16 KFP03593.1 - 5e-07 29.7 0.0 1.3e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP03593.1 - 3.6e-05 24.3 0.0 9.2e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP03593.1 - 7.3e-05 22.9 0.0 0.00018 21.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Y_phosphatase3 PF13350.6 KFP03593.1 - 9.7e-05 22.4 0.0 0.061 13.3 0.0 2.5 2 0 0 2 2 2 2 Tyrosine phosphatase family Ig_2 PF13895.6 KFP03593.1 - 0.00078 19.7 0.0 0.002 18.4 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain PTPlike_phytase PF14566.6 KFP03593.1 - 0.0035 17.5 0.0 0.16 12.1 0.0 2.6 2 0 0 2 2 2 1 Inositol hexakisphosphate Protocadherin PF08374.11 KFP03593.1 - 0.021 14.8 0.1 0.045 13.7 0.1 1.5 1 0 0 1 1 1 0 Protocadherin Ly49 PF08391.10 KFP03593.1 - 0.03 14.7 0.0 0.57 10.5 0.0 2.4 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region V-set PF07686.17 KFP03593.1 - 0.05 13.8 0.1 0.57 10.4 0.1 2.5 1 1 0 1 1 1 0 Immunoglobulin V-set domain DUF1310 PF07006.11 KFP03593.1 - 0.097 12.7 0.2 14 5.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1310) ECSCR PF15820.5 KFP03593.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator CABIT PF12736.7 KFP03594.1 - 5.8e-102 340.8 5.6 6.1e-53 179.9 0.2 2.2 2 0 0 2 2 2 2 Cell-cycle sustaining, positive selection, DUF1966 PF09260.11 KFP03594.1 - 0.024 14.9 0.0 0.061 13.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1966) Leg1 PF05612.12 KFP03595.1 - 3.9e-89 299.1 0.0 5.3e-89 298.6 0.0 1.2 1 0 0 1 1 1 1 Leg1 SOGA PF11365.8 KFP03596.1 - 4.2e-63 210.5 48.0 1.7e-31 109.2 1.1 5.2 5 1 1 6 6 6 3 Protein SOGA ERM PF00769.19 KFP03596.1 - 0.0015 18.4 6.5 0.0015 18.4 6.5 4.5 3 1 0 3 3 3 1 Ezrin/radixin/moesin family DUF2968 PF11180.8 KFP03596.1 - 0.0034 17.1 7.3 0.0034 17.1 7.3 3.8 2 1 1 3 3 3 1 Protein of unknown function (DUF2968) TSC22 PF01166.18 KFP03596.1 - 0.0094 16.2 0.3 0.0094 16.2 0.3 6.9 7 1 0 7 7 7 3 TSC-22/dip/bun family Halo_GVPC PF05465.13 KFP03596.1 - 0.036 14.3 0.6 0.092 13.0 0.6 1.7 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat SlyX PF04102.12 KFP03596.1 - 0.6 10.8 41.1 1.4 9.6 0.2 7.6 5 3 2 7 7 7 0 SlyX APG6_N PF17675.1 KFP03596.1 - 1.7 9.2 64.4 3.9 8.0 5.3 6.2 3 1 2 5 5 5 0 Apg6 coiled-coil region YabA PF06156.13 KFP03596.1 - 6.3 7.5 47.7 1.1 10.0 3.5 6.9 3 3 4 7 7 7 0 Initiation control protein YabA DUF4482 PF14818.6 KFP03597.1 - 1.3e-32 113.6 16.3 1.3e-32 113.6 16.3 4.1 3 1 1 4 4 4 1 Domain of unknown function (DUF4482) WWE PF02825.20 KFP03598.1 - 5.9e-16 58.8 5.2 6.3e-16 58.7 3.1 2.0 2 0 0 2 2 2 1 WWE domain zf-C3HC4_3 PF13920.6 KFP03598.1 - 3.9e-07 29.8 10.6 7.3e-07 29.0 10.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP03598.1 - 1.8e-05 24.5 9.4 4.3e-05 23.3 9.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP03598.1 - 0.00014 21.8 9.3 0.00032 20.6 9.0 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFP03598.1 - 0.00016 21.9 12.5 0.00028 21.2 12.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP03598.1 - 0.00047 19.9 12.0 0.00083 19.1 12.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP03598.1 - 0.0032 17.3 9.9 0.0061 16.4 9.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFP03598.1 - 0.016 15.4 10.6 0.016 15.4 10.6 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KFP03598.1 - 0.016 15.2 11.4 0.029 14.3 11.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_10 PF16685.5 KFP03598.1 - 0.028 14.5 7.4 0.051 13.7 7.4 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Yae1_N PF09811.9 KFP03599.1 - 4e-17 61.6 56.0 0.0095 15.6 6.7 5.3 1 1 1 2 2 2 1 Essential protein Yae1, N terminal AKAP7_RIRII_bdg PF10470.9 KFP03600.1 - 2.7 8.1 10.0 7.7 6.7 2.3 2.3 1 1 1 2 2 2 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein CENP-W PF15510.6 KFP03601.1 - 7.8e-16 58.1 0.3 8.2e-16 58.0 0.3 1.0 1 0 0 1 1 1 1 CENP-W protein CBFD_NFYB_HMF PF00808.23 KFP03601.1 - 0.0037 17.5 0.3 0.0044 17.3 0.3 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone UPF0020 PF01170.18 KFP03602.1 - 2.9e-11 43.4 0.0 8.7e-11 41.9 0.0 1.7 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 KFP03602.1 - 2.7e-05 23.6 0.0 5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase N6_N4_Mtase PF01555.18 KFP03602.1 - 0.0055 16.4 0.1 0.51 10.0 0.0 2.4 2 0 0 2 2 2 2 DNA methylase Eco57I PF07669.11 KFP03602.1 - 0.058 13.9 0.0 0.2 12.2 0.0 1.9 1 0 0 1 1 1 0 Eco57I restriction-modification methylase Costars PF14705.6 KFP03603.1 - 6.9e-34 115.9 0.1 8.4e-34 115.6 0.1 1.1 1 0 0 1 1 1 1 Costars DcpS_C PF11969.8 KFP03604.1 - 9.9e-31 106.6 0.0 1.2e-30 106.3 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KFP03604.1 - 2.5e-08 34.6 1.3 4e-08 33.9 1.3 1.4 1 1 0 1 1 1 1 HIT domain TLD PF07534.16 KFP03605.1 - 1.4e-38 132.3 0.5 1.5e-38 132.1 0.5 1.0 1 0 0 1 1 1 1 TLD HLH PF00010.26 KFP03606.1 - 3.2e-18 65.4 3.4 5e-18 64.8 3.4 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 KFP03606.1 - 3.8e-14 52.6 0.1 7e-14 51.7 0.1 1.4 1 0 0 1 1 1 1 Hairy Orange dCache_2 PF08269.11 KFP03606.1 - 0.0065 15.7 0.0 0.0074 15.5 0.0 1.1 1 0 0 1 1 1 1 Cache domain HTH_Crp_2 PF13545.6 KFP03606.1 - 0.1 12.6 1.7 0.26 11.3 1.7 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DUF3772 PF12607.8 KFP03606.1 - 0.19 11.5 3.2 2.3 8.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) HD_3 PF13023.6 KFP03607.1 - 1.2e-46 158.6 1.2 1.5e-46 158.4 1.2 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KFP03607.1 - 3.7e-16 59.4 0.7 4.7e-16 59.1 0.7 1.3 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KFP03607.1 - 0.00024 21.3 0.4 0.00043 20.5 0.4 1.4 1 0 0 1 1 1 1 HD domain DUF4259 PF14078.6 KFP03607.1 - 0.2 12.4 2.9 0.26 12.0 2.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4259) TPD52 PF04201.15 KFP03608.1 - 1.3e-61 207.0 4.4 1.7e-61 206.6 4.4 1.1 1 0 0 1 1 1 1 Tumour protein D52 family IBR PF01485.21 KFP03609.1 - 2e-18 66.4 28.5 1.4e-09 38.0 8.1 2.9 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-UDP PF14569.6 KFP03609.1 - 1.8 8.7 22.4 2.5 8.3 0.3 3.7 1 1 2 3 3 3 0 Zinc-binding RING-finger NKAIN PF05640.14 KFP03610.1 - 9.9e-81 269.9 6.4 1.1e-80 269.8 6.4 1.0 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein DUF1003 PF06210.11 KFP03610.1 - 6.1 7.0 5.5 4.8 7.3 4.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1003) Asp-B-Hydro_N PF05279.11 KFP03611.1 - 2.4e-07 31.1 1.7 2.4e-07 31.1 1.7 2.1 2 0 0 2 2 2 1 Aspartyl beta-hydroxylase N-terminal region CDC45 PF02724.14 KFP03611.1 - 0.25 9.6 13.4 0.3 9.3 13.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KFP03611.1 - 0.37 9.5 18.9 0.035 12.9 13.6 1.8 2 0 0 2 2 2 0 Presenilin DUF2839 PF10999.8 KFP03611.1 - 0.43 11.0 0.1 0.43 11.0 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2839) Mitofilin PF09731.9 KFP03611.1 - 1.1 8.0 32.1 1.6 7.5 32.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein AAA_13 PF13166.6 KFP03611.1 - 9.9 4.7 24.7 13 4.3 24.7 1.0 1 0 0 1 1 1 0 AAA domain CRAL_TRIO PF00650.20 KFP03612.1 - 1.5e-34 119.0 0.0 2.3e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFP03612.1 - 1.7e-08 34.7 0.0 2.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFP03612.1 - 2.1e-06 27.8 0.1 4.8e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Metallophos PF00149.28 KFP03613.1 - 5.9e-14 53.0 0.1 8e-14 52.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Lipocalin PF00061.23 KFP03614.1 - 6.5e-29 101.0 2.1 7.1e-29 100.9 2.1 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 KFP03614.1 - 7.5e-07 29.1 1.1 9.6e-07 28.8 1.1 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Myosin_N PF02736.19 KFP03614.1 - 0.89 9.4 6.0 2.8 7.8 0.3 3.0 2 1 1 3 3 3 0 Myosin N-terminal SH3-like domain PKI PF02827.16 KFP03615.1 - 7.4e-25 86.9 0.0 7.9e-25 86.9 0.0 1.0 1 0 0 1 1 1 1 cAMP-dependent protein kinase inhibitor Serinc PF03348.15 KFP03616.1 - 3.4e-176 586.4 13.5 3.8e-176 586.2 13.5 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Vert_HS_TF PF06546.11 KFP03617.1 - 2.2e-71 240.7 16.4 2.2e-71 240.7 16.4 1.7 2 0 0 2 2 2 1 Vertebrate heat shock transcription factor HSF_DNA-bind PF00447.17 KFP03617.1 - 3.2e-24 85.4 0.7 6.9e-24 84.3 0.7 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding bZIP_2 PF07716.15 KFP03617.1 - 0.017 15.2 1.6 0.046 13.8 1.6 1.8 1 0 0 1 1 1 0 Basic region leucine zipper HALZ PF02183.18 KFP03617.1 - 0.021 15.1 0.4 0.054 13.7 0.4 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper APG6_N PF17675.1 KFP03617.1 - 0.021 15.3 1.5 0.042 14.4 1.5 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region AATF-Che1 PF13339.6 KFP03617.1 - 0.087 13.5 3.1 0.064 13.9 1.1 1.8 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Trans_coact PF16805.5 KFP03617.1 - 0.15 12.2 1.8 0.41 10.8 1.8 1.7 1 0 0 1 1 1 0 Phage late-transcription coactivator LMBR1 PF04791.16 KFP03617.1 - 0.91 8.4 3.7 1.4 7.8 3.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein ZapB PF06005.12 KFP03617.1 - 1.2 9.7 7.7 3.3 8.2 7.7 1.8 1 0 0 1 1 1 0 Cell division protein ZapB Connexin PF00029.19 KFP03619.1 - 8.5e-95 317.0 2.4 1.3e-94 316.4 2.4 1.2 1 0 0 1 1 1 1 Connexin Connexin43 PF03508.13 KFP03619.1 - 4.6e-11 42.0 15.4 1e-10 41.0 15.4 1.6 1 0 0 1 1 1 1 Gap junction alpha-1 protein (Cx43) Connexin40_C PF16791.5 KFP03619.1 - 4.7e-06 27.8 1.7 7.5e-06 27.2 1.7 1.3 1 0 0 1 1 1 1 Connexin 40 C-terminal domain TEX29 PF15839.5 KFP03619.1 - 4.3 8.0 5.8 1.5 9.5 0.2 2.5 2 1 0 2 2 2 0 Testis-expressed sequence 29 protein MctB PF11382.8 KFP03620.1 - 0.063 13.0 0.1 0.12 12.1 0.0 1.4 1 1 0 1 1 1 0 Copper transport outer membrane protein, MctB BROMI PF14961.6 KFP03621.1 - 0 2037.3 26.5 0 2033.0 26.5 1.9 1 1 0 1 1 1 1 Broad-minded protein RabGAP-TBC PF00566.18 KFP03621.1 - 0.048 13.3 8.1 0.035 13.8 4.5 2.6 2 1 0 2 2 2 0 Rab-GTPase-TBC domain UBN_AB PF14075.6 KFP03621.1 - 0.053 13.2 2.3 3.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Ubinuclein conserved middle domain Glyco_hydro_47 PF01532.20 KFP03622.1 - 4.8e-155 516.9 0.0 5.5e-155 516.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.13 KFP03622.1 - 0.095 11.8 1.3 0.14 11.2 0.1 1.9 3 0 0 3 3 3 0 Glycosyl Hydrolase Family 88 TBPIP PF07106.13 KFP03622.1 - 0.13 12.2 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain MCM PF00493.23 KFP03623.1 - 2.2e-77 259.2 0.0 3.8e-77 258.4 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFP03623.1 - 8.8e-22 77.3 4.0 2.6e-21 75.8 4.0 1.7 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFP03623.1 - 3.9e-16 59.2 1.9 2e-15 57.0 2.0 2.1 2 0 0 2 2 2 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KFP03623.1 - 7.6e-09 35.3 0.1 0.00035 20.0 0.0 2.7 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFP03623.1 - 2e-07 31.1 0.0 3.9e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFP03623.1 - 0.0064 16.3 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFP03623.1 - 0.046 13.4 0.0 5.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.6 KFP03623.1 - 0.078 13.4 0.1 0.31 11.4 0.1 2.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KFP03623.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 KFP03623.1 - 0.21 11.3 0.9 0.5 10.1 0.1 2.0 2 1 0 2 2 2 0 AAA domain Rota_NS6 PF04866.12 KFP03623.1 - 2.1 8.6 7.4 14 6.0 0.2 3.3 2 1 1 3 3 3 0 Rotavirus non-structural protein 6 ASF1_hist_chap PF04729.13 KFP03624.1 - 6.7e-72 240.5 0.1 8.3e-72 240.2 0.1 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone UPF0154 PF03672.13 KFP03624.1 - 0.074 13.1 0.0 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0154) Phospholamban PF04272.14 KFP03625.1 - 4.1e-33 112.6 8.4 4.5e-33 112.5 8.4 1.0 1 0 0 1 1 1 1 Phospholamban Sarcolipin PF05366.11 KFP03625.1 - 0.0066 16.1 4.5 0.01 15.5 4.5 1.4 1 0 0 1 1 1 1 Sarcolipin Anoctamin PF04547.12 KFP03625.1 - 0.11 11.3 0.4 0.11 11.4 0.4 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel SLC35F PF06027.12 KFP03626.1 - 1e-120 402.8 19.3 1.2e-120 402.6 19.3 1.0 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 KFP03626.1 - 1.9e-14 54.0 24.5 3.1e-09 37.1 11.2 2.0 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 KFP03626.1 - 2.6e-09 36.5 7.7 2.6e-09 36.5 7.7 1.9 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Mg_trans_NIPA PF05653.14 KFP03626.1 - 0.001 18.3 2.8 0.001 18.3 2.8 1.9 1 1 0 1 1 1 1 Magnesium transporter NIPA DUF809 PF05663.11 KFP03626.1 - 0.12 12.5 0.1 0.12 12.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF809) Prenyltransf PF01255.19 KFP03627.1 - 1.8e-08 34.2 0.0 2e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF5099 PF17025.5 KFP03627.1 - 0.043 14.2 0.1 0.16 12.4 0.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5099) Methyltransf_11 PF08241.12 KFP03627.1 - 0.12 13.0 0.1 0.19 12.4 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain LRR_8 PF13855.6 KFP03628.1 - 7e-55 182.6 52.7 3.8e-13 49.0 2.0 7.2 6 1 0 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFP03628.1 - 1.3e-32 111.2 55.8 4.9e-06 26.8 1.4 9.7 2 2 8 12 12 12 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP03628.1 - 2.2e-11 42.7 38.1 0.28 11.9 0.1 13.7 14 1 0 14 14 14 3 Leucine Rich Repeat LRR_5 PF13306.6 KFP03628.1 - 9.8e-11 41.7 1.4 2.3e-05 24.3 0.3 3.7 2 1 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP03628.1 - 1e-09 38.2 27.2 0.0056 16.2 0.7 5.8 1 1 3 6 6 6 4 Leucine-rich repeat LRR_6 PF13516.6 KFP03628.1 - 4.6e-05 23.1 33.4 0.37 11.0 0.1 10.8 11 0 0 11 11 11 4 Leucine Rich repeat FNIP PF05725.12 KFP03628.1 - 0.58 10.4 0.0 0.58 10.4 0.0 4.3 3 2 0 3 3 3 0 FNIP Repeat PDZ PF00595.24 KFP03630.1 - 3.1e-16 59.5 1.8 4e-16 59.1 0.5 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFP03630.1 - 1.1e-08 34.7 0.1 2.3e-08 33.7 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP03630.1 - 5.5e-05 23.4 0.5 0.00045 20.5 0.1 2.4 2 0 0 2 2 2 1 PDZ domain DUF903 PF06004.12 KFP03630.1 - 0.016 15.1 0.1 0.034 14.0 0.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) bZIP_2 PF07716.15 KFP03630.1 - 0.018 15.1 7.7 0.018 15.1 7.7 2.6 2 0 0 2 2 2 0 Basic region leucine zipper JAKMIP_CC3 PF16034.5 KFP03630.1 - 0.63 10.0 8.4 0.062 13.3 2.1 2.1 1 1 0 2 2 2 0 JAKMIP CC3 domain DivIC PF04977.15 KFP03630.1 - 1.5 8.6 12.8 1.3 8.9 2.8 2.7 2 0 0 2 2 2 0 Septum formation initiator Atg14 PF10186.9 KFP03630.1 - 3.3 6.7 8.6 4.6 6.2 8.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PRKG1_interact PF15898.5 KFP03630.1 - 3.4 8.6 11.6 1.7 9.6 9.1 1.7 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain F5_F8_type_C PF00754.25 KFP03631.1 - 3.4e-26 91.9 2.3 3.4e-26 91.9 2.3 1.7 2 0 0 2 2 2 1 F5/8 type C domain CUB PF00431.20 KFP03631.1 - 3.4e-19 69.2 0.3 8.5e-19 67.9 0.0 1.9 2 0 0 2 2 2 1 CUB domain LCCL PF03815.19 KFP03631.1 - 3.8e-14 52.6 0.1 8.9e-14 51.4 0.1 1.6 1 0 0 1 1 1 1 LCCL domain Pkinase_Tyr PF07714.17 KFP03632.1 - 8.7e-96 320.2 0.0 1.5e-95 319.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase fn3 PF00041.21 KFP03632.1 - 2.3e-43 146.4 32.5 8.6e-08 32.4 0.0 10.0 9 0 0 9 9 9 8 Fibronectin type III domain Pkinase PF00069.25 KFP03632.1 - 5.2e-41 140.8 0.0 8.5e-41 140.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Vg_Tdu PF07545.14 KFP03633.1 - 1e-19 70.0 0.4 1.8e-19 69.2 0.4 1.4 1 0 0 1 1 1 1 Vestigial/Tondu family FAM181 PF15238.6 KFP03633.1 - 0.31 10.8 7.0 0.06 13.2 3.2 1.7 2 0 0 2 2 2 0 FAM181 DUF3123 PF11321.8 KFP03633.1 - 0.49 11.1 12.7 0.47 11.1 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3123) SelP_N PF04592.14 KFP03633.1 - 4.3 6.7 10.6 6.4 6.1 10.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RFX_DNA_binding PF02257.15 KFP03634.1 - 3.4e-31 107.7 0.1 1.1e-30 106.1 0.1 1.9 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 KFP03634.1 - 0.093 13.2 0.1 0.24 11.9 0.1 1.7 1 0 0 1 1 1 0 Poxvirus D5 protein-like DUF1075 PF06388.11 KFP03635.1 - 8.5e-39 132.3 0.3 1.1e-38 132.0 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1075) Arm PF00514.23 KFP03636.1 - 6e-89 289.7 15.2 7.7e-13 48.0 0.6 8.7 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KFP03636.1 - 2.3e-27 95.2 1.7 5.5e-27 94.0 1.7 1.7 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.6 KFP03636.1 - 1.5e-23 83.0 0.0 5.9e-07 29.8 0.0 5.0 3 1 1 5 5 4 4 HEAT repeats HEAT_EZ PF13513.6 KFP03636.1 - 5.7e-23 81.0 4.3 2.1e-07 31.3 0.0 6.1 4 2 1 5 5 5 4 HEAT-like repeat Arm_3 PF16186.5 KFP03636.1 - 8.9e-23 79.6 3.2 2.9e-22 78.0 2.5 2.3 3 0 0 3 3 3 1 Atypical Arm repeat HEAT PF02985.22 KFP03636.1 - 4.4e-19 66.9 4.7 0.00049 20.1 0.0 8.3 9 0 0 9 9 8 3 HEAT repeat V-ATPase_H_C PF11698.8 KFP03636.1 - 4.8e-06 26.7 0.0 0.13 12.4 0.0 4.5 3 3 2 5 5 5 1 V-ATPase subunit H RICTOR_V PF14668.6 KFP03636.1 - 1.1e-05 25.6 0.5 0.19 12.0 0.0 4.6 4 2 1 5 5 4 1 Rapamycin-insensitive companion of mTOR, domain 5 Adaptin_N PF01602.20 KFP03636.1 - 0.00014 20.6 0.0 0.002 16.8 0.0 2.3 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.13 KFP03636.1 - 0.00036 20.1 0.0 0.21 11.0 0.0 3.0 1 1 2 3 3 3 1 Armadillo-like V-ATPase_H_N PF03224.14 KFP03636.1 - 0.00078 18.8 0.1 0.55 9.5 0.0 3.5 2 2 1 3 3 3 1 V-ATPase subunit H HEAT_PBS PF03130.16 KFP03636.1 - 0.002 18.6 0.4 6.5 7.7 0.0 4.9 5 0 0 5 5 4 1 PBS lyase HEAT-like repeat NopRA1 PF16201.5 KFP03636.1 - 0.011 15.4 0.0 4.1 6.9 0.0 3.6 1 1 1 2 2 2 0 Nucleolar pre-ribosomal-associated protein 1 Atx10homo_assoc PF09759.9 KFP03636.1 - 0.02 14.9 0.1 0.37 10.8 0.0 2.6 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain CTNNBL PF08216.11 KFP03636.1 - 0.064 13.4 0.0 14 5.9 0.0 3.7 4 0 0 4 4 4 0 Catenin-beta-like, Arm-motif containing nuclear UNC45-central PF11701.8 KFP03636.1 - 0.087 12.8 0.1 0.91 9.5 0.0 2.5 2 2 0 2 2 2 0 Myosin-binding striated muscle assembly central Big_5 PF13205.6 KFP03636.1 - 0.14 12.8 0.1 0.27 12.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain NUSAP PF16006.5 KFP03636.1 - 0.22 11.3 4.4 0.29 10.8 4.4 1.2 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein Peptidase_C78 PF07910.13 KFP03637.1 - 3.4e-70 235.8 0.0 5.4e-70 235.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 KFP03637.1 - 0.0015 18.0 0.1 0.0022 17.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase family C54 DDRGK PF09756.9 KFP03637.1 - 0.022 14.3 3.5 0.036 13.7 3.5 1.4 1 0 0 1 1 1 0 DDRGK domain Zn-C2H2_12 PF18112.1 KFP03637.1 - 1.1 9.7 4.2 5.3 7.6 4.2 2.2 1 1 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain Sulfotransfer_1 PF00685.27 KFP03638.1 - 1.3e-74 251.0 0.3 1.6e-74 250.8 0.3 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP03638.1 - 3.9e-07 30.7 0.0 0.00023 21.6 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase family RWD PF05773.22 KFP03639.1 - 5.8e-17 62.0 0.1 5.8e-17 62.0 0.1 1.7 2 1 0 2 2 2 1 RWD domain DFRP_C PF16543.5 KFP03639.1 - 5.4e-07 30.0 6.1 5.4e-07 30.0 6.1 2.4 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 DUF445 PF04286.12 KFP03639.1 - 0.0026 17.6 5.3 0.003 17.4 5.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) ACC_central PF08326.12 KFP03639.1 - 0.0053 15.0 3.3 0.0059 14.9 3.3 1.0 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Folliculin PF11704.8 KFP03639.1 - 0.04 13.8 1.8 0.062 13.2 1.8 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF3929 PF13066.6 KFP03639.1 - 0.044 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3929) SeleniumBinding PF11524.8 KFP03639.1 - 0.11 13.0 0.6 0.38 11.2 0.5 1.9 1 1 0 1 1 1 0 Selenium binding protein A_deaminase_N PF08451.11 KFP03639.1 - 0.71 10.2 6.3 1.1 9.7 5.8 1.6 1 1 0 1 1 1 0 Adenosine/AMP deaminase N-terminal DHHA1 PF02272.19 KFP03639.1 - 0.82 10.1 6.7 1.4 9.4 6.1 1.7 1 1 1 2 2 2 0 DHHA1 domain Ca_hom_mod PF14798.6 KFP03640.1 - 2.1e-84 282.6 3.8 2.5e-84 282.4 3.8 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator Wzy_C PF04932.15 KFP03640.1 - 1.5 8.4 5.4 1.8 8.2 0.0 2.5 2 1 0 2 2 2 0 O-Antigen ligase TRAPP PF04051.16 KFP03641.1 - 3.2e-29 101.5 0.0 3.6e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ca_hom_mod PF14798.6 KFP03642.1 - 2.9e-87 292.0 12.9 3.4e-87 291.7 12.9 1.1 1 0 0 1 1 1 1 Calcium homeostasis modulator LRR19-TM PF15176.6 KFP03642.1 - 0.051 13.6 2.0 0.092 12.8 0.2 2.3 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF5010_C PF18099.1 KFP03642.1 - 0.19 11.9 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 DUF5010 C-terminal domain DUF4962 PF16332.5 KFP03643.1 - 1.6e-07 30.2 3.7 1.6e-07 30.2 3.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4962) Hepar_II_III PF07940.13 KFP03643.1 - 0.037 13.6 0.0 3.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Heparinase II/III-like protein SYF2 PF08231.12 KFP03643.1 - 0.073 13.5 1.3 0.15 12.4 1.3 1.5 1 0 0 1 1 1 0 SYF2 splicing factor DUF3340 PF11818.8 KFP03643.1 - 0.69 10.1 6.5 1.3 9.2 6.5 1.3 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Glyco_hydro_38N PF01074.22 KFP03644.1 - 1.3e-79 267.6 3.5 1.3e-79 267.6 3.5 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KFP03644.1 - 5.5e-25 88.7 0.3 9.7e-25 87.9 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KFP03644.1 - 1.2e-19 70.3 0.1 3.2e-19 68.9 0.1 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KFP03644.1 - 4.7e-09 36.2 0.0 1.1e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain S_100 PF01023.19 KFP03645.1 - 3.2e-20 71.6 0.1 9.9e-20 70.0 0.0 1.9 2 0 0 2 2 2 1 S-100/ICaBP type calcium binding domain EF-hand_7 PF13499.6 KFP03645.1 - 1.3e-08 35.1 0.4 1.6e-08 34.8 0.4 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP03645.1 - 2.8e-07 29.9 1.1 0.00031 20.5 0.5 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KFP03645.1 - 5.3e-05 22.5 4.9 5.9e-05 22.3 1.1 2.5 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 KFP03645.1 - 0.0021 17.9 1.2 0.0033 17.2 1.2 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KFP03645.1 - 0.03 13.8 4.3 0.23 11.0 2.4 2.5 2 0 0 2 2 2 0 EF hand EF-hand_4 PF12763.7 KFP03645.1 - 0.084 12.8 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand DUF4603 PF15376.6 KFP03646.1 - 0 2273.8 63.0 0 1612.7 24.3 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4603) Transglut_i_TM PF14400.6 KFP03646.1 - 0.085 12.9 0.1 0.085 12.9 0.1 2.2 2 0 0 2 2 2 0 Inactive transglutaminase fused to 7 transmembrane helices SWIRM PF04433.17 KFP03647.1 - 0.036 14.4 0.6 0.12 12.7 0.0 2.2 2 1 0 2 2 2 0 SWIRM domain Pertussis_S1 PF02917.14 KFP03647.1 - 0.045 13.5 0.0 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Pertussis toxin, subunit 1 GrpE PF01025.19 KFP03648.1 - 1.3e-46 158.3 3.9 1.5e-46 158.1 3.9 1.1 1 0 0 1 1 1 1 GrpE DUF2205 PF10224.9 KFP03648.1 - 0.025 14.5 3.8 0.025 14.5 3.8 1.7 1 1 1 2 2 2 0 Short coiled-coil protein LOH1CR12 PF10158.9 KFP03648.1 - 0.027 14.5 1.5 0.039 14.0 1.5 1.3 1 0 0 1 1 1 0 Tumour suppressor protein CRR7 PF12095.8 KFP03648.1 - 0.044 14.2 2.1 0.044 14.2 2.1 1.9 2 1 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 DUF1993 PF09351.10 KFP03648.1 - 0.073 13.2 2.2 5.8 7.0 1.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) DUF3391 PF11871.8 KFP03648.1 - 0.22 12.0 5.4 0.42 11.1 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) POX PF07526.11 KFP03648.1 - 0.23 12.0 4.1 0.39 11.3 4.1 1.3 1 0 0 1 1 1 0 Associated with HOX AvrM-A PF18241.1 KFP03648.1 - 0.36 11.2 7.1 0.54 10.7 7.1 1.3 1 0 0 1 1 1 0 Flax-rust effector AvrM-A Connexin PF00029.19 KFP03648.1 - 0.59 9.9 1.9 0.75 9.5 1.9 1.1 1 0 0 1 1 1 0 Connexin DUF3347 PF11827.8 KFP03648.1 - 0.63 10.2 6.0 0.8 9.9 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) TERB2 PF15101.6 KFP03648.1 - 0.71 9.9 3.7 0.96 9.5 3.7 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4407 PF14362.6 KFP03648.1 - 5.7 6.2 6.9 7.1 5.9 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hexapep PF00132.24 KFP03649.1 - 9.9e-05 21.9 15.7 0.0003 20.4 3.8 3.9 4 1 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Yeast-kill-tox PF09207.11 KFP03649.1 - 0.027 15.1 0.6 0.039 14.6 0.6 1.3 1 0 0 1 1 1 0 Yeast killer toxin RRM_1 PF00076.22 KFP03650.1 - 6.3e-12 45.1 0.0 9.4e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIE_beta PF02186.15 KFP03651.1 - 5.2e-21 74.7 0.1 5.2e-21 74.7 0.1 2.3 3 0 0 3 3 3 1 TFIIE beta subunit core domain TFA2_Winged_2 PF18121.1 KFP03651.1 - 2.4e-10 40.0 0.1 5.4e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 PDZ PF00595.24 KFP03651.1 - 0.043 14.2 0.1 0.096 13.0 0.1 1.5 1 0 0 1 1 1 0 PDZ domain EF-hand_11 PF08976.11 KFP03651.1 - 0.044 14.6 0.0 0.081 13.8 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain DUF4713 PF15831.5 KFP03652.1 - 5.2e-22 78.0 7.8 6.4e-22 77.8 7.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4713) Baculo_F PF12259.8 KFP03652.1 - 0.014 13.9 0.6 0.014 13.9 0.6 1.1 1 0 0 1 1 1 0 Baculovirus F protein Gemini_mov PF01708.16 KFP03652.1 - 0.08 12.7 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 Geminivirus putative movement protein EVC2_like PF12297.8 KFP03652.1 - 0.11 11.1 0.1 0.12 11.0 0.1 1.0 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein PurA PF04845.13 KFP03653.1 - 2.8e-106 353.8 0.0 3.3e-106 353.5 0.0 1.0 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein DUF3276 PF11680.8 KFP03653.1 - 0.18 12.0 6.4 6.3 6.9 0.3 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3276) Metallophos PF00149.28 KFP03654.1 - 2.5e-35 122.8 0.6 3.8e-35 122.3 0.5 1.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KFP03654.1 - 0.017 14.7 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF5378 PF17349.2 KFP03654.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Pyr_redox_2 PF07992.14 KFP03655.1 - 6.8e-49 166.7 0.2 1.6e-48 165.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFP03655.1 - 7.6e-35 119.5 0.5 1.4e-34 118.7 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFP03655.1 - 3.7e-17 62.7 0.3 1.6e-16 60.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFP03655.1 - 6.6e-08 32.2 0.0 9.1e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFP03655.1 - 0.038 13.1 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) TMEM154 PF15102.6 KFP03656.1 - 9.1e-05 22.4 0.1 0.00011 22.1 0.1 1.1 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 KFP03656.1 - 0.00012 22.8 0.3 0.00021 22.1 0.3 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Vpu PF00558.19 KFP03656.1 - 0.0018 18.0 0.2 0.0026 17.5 0.2 1.2 1 0 0 1 1 1 1 Vpu protein EGF_2 PF07974.13 KFP03656.1 - 0.0033 17.8 6.0 0.0033 17.8 6.0 2.2 2 0 0 2 2 1 1 EGF-like domain TMEM52 PF14979.6 KFP03656.1 - 0.0037 17.2 0.5 0.0048 16.8 0.5 1.2 1 0 0 1 1 1 1 Transmembrane 52 Laminin_EGF PF00053.24 KFP03656.1 - 0.0055 16.8 3.1 0.0055 16.8 3.1 2.1 2 0 0 2 2 2 1 Laminin EGF domain PAG PF15347.6 KFP03656.1 - 0.0086 15.1 0.1 0.011 14.8 0.1 1.0 1 0 0 1 1 1 1 Phosphoprotein associated with glycosphingolipid-enriched Rax2 PF12768.7 KFP03656.1 - 0.011 15.2 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Shisa PF13908.6 KFP03656.1 - 0.017 15.3 2.4 0.017 15.3 2.4 1.3 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Sigma_reg_N PF13800.6 KFP03656.1 - 0.019 15.2 0.0 0.026 14.8 0.0 1.1 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DAG1 PF05454.11 KFP03656.1 - 0.024 14.0 0.3 0.028 13.8 0.3 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Comm PF15957.5 KFP03656.1 - 0.044 14.1 0.0 0.06 13.7 0.0 1.2 1 0 0 1 1 1 0 Commissureless TRP PF06011.12 KFP03656.1 - 0.044 12.5 0.3 0.054 12.2 0.3 1.0 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Baculo_F PF12259.8 KFP03656.1 - 0.047 12.2 0.3 0.055 12.0 0.3 1.1 1 0 0 1 1 1 0 Baculovirus F protein FAM176 PF14851.6 KFP03656.1 - 0.058 13.0 0.1 0.065 12.9 0.1 1.1 1 0 0 1 1 1 0 FAM176 family Protocadherin PF08374.11 KFP03656.1 - 0.06 13.3 0.1 0.076 13.0 0.1 1.2 1 0 0 1 1 1 0 Protocadherin DUF5385 PF17359.2 KFP03656.1 - 0.08 12.5 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) WBP-1 PF11669.8 KFP03656.1 - 0.092 13.4 5.6 0.16 12.6 5.6 1.5 1 1 0 1 1 1 0 WW domain-binding protein 1 SIT PF15330.6 KFP03656.1 - 0.1 13.0 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT LRR19-TM PF15176.6 KFP03656.1 - 0.17 11.9 0.2 0.25 11.3 0.2 1.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain AJAP1_PANP_C PF15298.6 KFP03656.1 - 0.17 12.0 1.5 0.29 11.3 1.5 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Sec66 PF09802.9 KFP03656.1 - 0.18 11.4 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 FAM163 PF15069.6 KFP03656.1 - 1.1 9.7 6.3 0.17 12.3 2.0 1.7 1 1 1 2 2 2 0 FAM163 family ETRAMP PF09716.10 KFP03656.1 - 7.1 6.8 5.8 37 4.5 6.0 1.8 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) PAP1 PF08601.10 KFP03657.1 - 0.7 9.6 6.0 0.69 9.6 6.0 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Pkinase PF00069.25 KFP03658.1 - 2.8e-74 249.8 0.0 4.1e-74 249.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP03658.1 - 1.6e-37 129.2 0.0 1.1e-36 126.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP03658.1 - 3.5e-05 23.3 0.0 0.00013 21.5 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFP03658.1 - 0.0002 20.5 0.1 0.00035 19.6 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KFP03658.1 - 0.00046 19.8 0.1 0.00089 18.9 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KFP03658.1 - 0.014 14.8 0.0 0.034 13.5 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP03658.1 - 0.03 14.3 0.0 0.25 11.2 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family MdcG PF10620.9 KFP03658.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG AP1AR PF15745.5 KFP03659.1 - 1.2e-150 500.7 10.1 1.4e-150 500.5 10.1 1.0 1 0 0 1 1 1 1 AP-1 complex-associated regulatory protein PA26 PF04636.13 KFP03659.1 - 7.3 5.4 7.8 5.9 5.7 6.8 1.3 1 1 0 1 1 1 0 PA26 p53-induced protein (sestrin) FHA PF00498.26 KFP03660.1 - 0.0017 18.7 0.0 0.0024 18.2 0.0 1.2 1 0 0 1 1 1 1 FHA domain Alpha_kinase PF02816.18 KFP03661.1 - 9.3e-46 156.3 0.8 1.6e-45 155.5 0.8 1.4 1 0 0 1 1 1 1 Alpha-kinase family AAA_12 PF13087.6 KFP03662.1 - 1.3e-52 178.3 0.0 3e-52 177.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFP03662.1 - 1.7e-26 93.6 0.0 3.4e-19 69.7 0.2 2.5 1 1 1 2 2 2 2 AAA domain zf-GRF PF06839.12 KFP03662.1 - 1.5e-14 53.8 0.1 3.3e-14 52.7 0.1 1.6 1 0 0 1 1 1 1 GRF zinc finger Viral_helicase1 PF01443.18 KFP03662.1 - 5.8e-08 32.8 1.1 0.042 13.6 0.1 3.5 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KFP03662.1 - 0.0026 17.5 0.0 0.036 13.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KFP03662.1 - 0.0082 16.0 0.1 0.02 14.7 0.1 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KFP03662.1 - 0.014 15.7 0.0 0.05 13.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain UvrD_C PF13361.6 KFP03662.1 - 0.044 13.2 0.3 3.7 6.8 0.0 2.6 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain SNN_linker PF09050.10 KFP03662.1 - 4.3 7.2 5.1 16 5.3 1.0 2.5 2 0 0 2 2 2 0 Stannin unstructured linker RRM_3 PF08777.11 KFP03663.1 - 4.3e-28 97.3 0.1 6.1e-28 96.9 0.1 3.9 5 0 0 5 5 5 2 RNA binding motif RRM_1 PF00076.22 KFP03663.1 - 7.6e-21 73.7 0.0 9.4e-17 60.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) La PF05383.17 KFP03663.1 - 9.9e-21 73.6 0.0 2.6e-20 72.2 0.0 1.8 1 0 0 1 1 1 1 La domain Nup35_RRM_2 PF14605.6 KFP03663.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Exo_endo_phos PF03372.23 KFP03665.1 - 1.7e-21 76.8 0.0 1e-20 74.3 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 KFP03665.1 - 3.2e-12 46.0 12.7 2.5e-11 43.1 10.0 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFP03665.1 - 8.3e-10 38.8 16.9 1e-07 32.1 3.0 3.5 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP03665.1 - 0.013 15.0 0.9 0.029 13.9 0.9 1.5 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 KFP03665.1 - 0.038 14.1 11.2 3.9 7.8 2.7 4.1 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 KFP03665.1 - 0.098 13.3 18.5 8.1 7.4 0.1 5.7 5 0 0 5 5 5 0 Leucine Rich Repeat IL8 PF00048.20 KFP03666.1 - 4.4e-15 55.6 0.4 4.8e-15 55.5 0.4 1.0 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like IL8 PF00048.20 KFP03667.1 - 3.6e-16 59.0 1.0 4e-16 58.9 1.0 1.0 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Gp_UL130 PF11668.8 KFP03667.1 - 0.083 12.8 0.0 0.089 12.7 0.0 1.0 1 0 0 1 1 1 0 HCMV glycoprotein pUL130 Cyclin_N PF00134.23 KFP03669.1 - 1.6e-16 60.2 0.2 1.6e-16 60.2 0.2 2.2 1 1 1 2 2 2 1 Cyclin, N-terminal domain Cyclin_N PF00134.23 KFP03670.1 - 8.8e-24 83.7 0.8 6.8e-23 80.8 0.2 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP03670.1 - 0.00054 20.0 4.1 0.0013 18.8 2.2 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain Septin PF00735.18 KFP03671.1 - 7.6e-99 330.5 1.3 7.6e-99 330.5 1.3 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KFP03671.1 - 5e-07 29.8 0.0 5e-07 29.8 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF3080 PF11279.8 KFP03671.1 - 9e-05 21.8 6.5 0.00014 21.2 6.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3080) Roc PF08477.13 KFP03671.1 - 0.00039 20.6 0.0 0.0014 18.8 0.0 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KFP03671.1 - 0.00041 20.8 0.1 0.0014 19.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFP03671.1 - 0.0005 20.3 0.3 0.0017 18.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain Ras PF00071.22 KFP03671.1 - 0.002 17.8 0.0 0.006 16.2 0.0 1.9 1 0 0 1 1 1 1 Ras family AAA_23 PF13476.6 KFP03671.1 - 0.011 16.3 21.8 0.24 11.9 0.3 2.6 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KFP03671.1 - 0.012 15.4 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 KFP03671.1 - 0.02 14.4 8.6 0.97 8.9 0.1 3.5 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 KFP03671.1 - 0.03 13.8 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Dynamin_N PF00350.23 KFP03671.1 - 0.061 13.4 9.7 0.72 9.9 0.1 3.1 2 1 0 2 2 2 0 Dynamin family Fzo_mitofusin PF04799.13 KFP03671.1 - 0.072 12.6 8.1 0.21 11.2 8.1 1.8 1 0 0 1 1 1 0 fzo-like conserved region RsgA_GTPase PF03193.16 KFP03671.1 - 0.076 12.9 6.7 0.2 11.6 0.0 3.1 3 1 0 3 3 3 0 RsgA GTPase Atg14 PF10186.9 KFP03671.1 - 0.29 10.2 15.0 0.43 9.6 13.5 1.9 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF87 PF01935.17 KFP03671.1 - 0.34 11.0 7.8 2.2 8.3 0.0 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain ABC_tran PF00005.27 KFP03671.1 - 1.2 9.7 6.8 0.25 11.8 0.1 2.6 2 1 0 2 2 2 0 ABC transporter Ank_5 PF13857.6 KFP03672.1 - 1.1e-11 44.7 0.0 1.2e-08 35.0 0.0 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KFP03672.1 - 1.2e-07 31.9 0.5 1.8e-05 25.0 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 KFP03672.1 - 3.2e-07 30.8 0.0 4.2e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP03672.1 - 3.7e-05 23.8 0.2 0.015 15.7 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KFP03672.1 - 6.5e-05 23.4 0.2 0.00074 20.0 0.2 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Gal-bind_lectin PF00337.22 KFP03673.1 - 2.6e-28 98.2 0.0 3e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin CD36 PF01130.21 KFP03674.1 - 1.3e-149 498.7 0.5 1.5e-149 498.5 0.5 1.0 1 0 0 1 1 1 1 CD36 family Nup54 PF13874.6 KFP03675.1 - 5.5e-46 156.2 2.4 5.5e-46 156.2 2.4 1.9 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nup54_C PF18437.1 KFP03675.1 - 6e-18 64.5 6.8 6e-18 64.5 6.8 2.8 2 0 0 2 2 2 1 Nup54 C-terminal interacting domain XhlA PF10779.9 KFP03675.1 - 0.071 13.3 1.2 0.26 11.5 1.2 1.9 1 0 0 1 1 1 0 Haemolysin XhlA Regulator_TrmB PF11495.8 KFP03675.1 - 0.21 10.7 1.1 21 4.2 0.1 2.9 2 1 0 3 3 3 0 Archaeal transcriptional regulator TrmB Keratin_2_head PF16208.5 KFP03675.1 - 0.39 10.8 19.4 0.74 9.9 19.4 1.4 1 0 0 1 1 1 0 Keratin type II head KRTAP PF11759.8 KFP03675.1 - 0.57 10.8 15.2 1.4 9.5 15.2 1.6 1 0 0 1 1 1 0 Keratin-associated matrix TBCC_N PF16752.5 KFP03675.1 - 6.9 7.1 11.1 1.3 9.5 3.7 3.2 2 1 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain Metallophos PF00149.28 KFP03676.1 - 4.3e-27 96.0 0.0 6.5e-21 75.8 0.0 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 KFP03676.1 - 1.6e-17 63.7 6.4 7.3e-11 42.4 2.9 3.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KFP03676.1 - 3.6e-17 60.6 1.9 5.9e-06 25.5 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KFP03676.1 - 1.6e-14 52.5 1.8 0.0016 18.2 0.1 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 KFP03676.1 - 1.9e-11 43.6 3.3 1.6e-05 24.6 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain pair PPP5 PF08321.12 KFP03676.1 - 2e-10 40.8 4.6 6.4e-10 39.2 0.0 3.4 3 1 0 3 3 3 1 PPP5 TPR repeat region EF-hand_5 PF13202.6 KFP03676.1 - 9.3e-09 34.4 4.6 0.00047 19.5 0.0 3.4 3 0 0 3 3 3 2 EF hand IQ PF00612.27 KFP03676.1 - 0.00012 21.6 1.4 0.00031 20.3 1.4 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif EF-hand_4 PF12763.7 KFP03676.1 - 0.00014 21.7 4.4 0.025 14.5 0.3 3.4 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFP03676.1 - 0.0011 19.3 0.0 2 8.8 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KFP03676.1 - 0.003 17.9 0.5 4.6 7.6 0.3 2.9 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region HIT PF01230.23 KFP03676.1 - 0.13 13.0 0.5 1.1 10.0 0.0 2.7 3 0 0 3 3 3 0 HIT domain SDA1 PF05285.12 KFP03678.1 - 6.3e-67 226.5 39.1 2.9e-38 132.2 3.5 3.1 2 1 1 3 3 3 3 SDA1 NUC130_3NT PF08158.12 KFP03678.1 - 1e-26 93.0 3.4 3.1e-26 91.5 1.0 3.0 3 0 0 3 3 3 1 NUC130/3NT domain Ribosomal_L22 PF00237.19 KFP03678.1 - 0.0092 16.2 0.6 0.039 14.2 0.1 2.3 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Ig_J_chain PF15097.6 KFP03679.1 - 3e-64 214.9 6.7 3.3e-64 214.8 6.7 1.0 1 0 0 1 1 1 1 Immunoglobulin J chain IL8 PF00048.20 KFP03679.1 - 0.068 13.3 3.4 0.72 10.0 0.4 2.5 2 0 0 2 2 2 0 Small cytokines (intecrine/chemokine), interleukin-8 like Sas10 PF09368.10 KFP03680.1 - 2e-26 92.2 8.0 2e-26 92.2 8.0 2.4 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KFP03680.1 - 5.4e-17 62.2 3.5 7e-17 61.8 0.1 2.5 2 1 0 2 2 2 1 Sas10/Utp3/C1D family RUN PF02759.19 KFP03681.1 - 3.1e-20 72.5 0.5 1.4e-19 70.4 0.0 2.3 2 0 0 2 2 2 1 RUN domain Trimer_CC PF08954.11 KFP03681.1 - 0.0031 17.0 5.5 0.1 12.2 0.0 3.1 3 0 0 3 3 3 2 Trimerisation motif Asparaginase PF00710.20 KFP03681.1 - 0.069 12.7 0.2 0.34 10.4 0.2 2.0 2 0 0 2 2 2 0 Asparaginase, N-terminal APC_N_CC PF16689.5 KFP03681.1 - 0.72 10.0 8.8 8.7 6.5 0.7 3.2 2 1 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain ATG16 PF08614.11 KFP03681.1 - 1 9.6 30.3 6.1 7.0 30.3 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF641 PF04859.12 KFP03681.1 - 1.4 9.2 21.4 0.41 11.0 1.9 3.2 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) KASH_CCD PF14662.6 KFP03681.1 - 1.9 8.3 34.9 4.4 7.1 27.7 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF4407 PF14362.6 KFP03681.1 - 2.7 7.3 19.0 6.2 6.1 17.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) XhlA PF10779.9 KFP03681.1 - 2.9 8.1 10.4 0.86 9.8 2.4 2.8 2 0 0 2 2 2 0 Haemolysin XhlA Macoilin PF09726.9 KFP03681.1 - 3.8 6.0 29.3 7.5 5.0 29.3 1.5 1 1 0 1 1 1 0 Macoilin family DUF1664 PF07889.12 KFP03681.1 - 5.3 7.1 23.4 0.14 12.2 2.9 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 KFP03681.1 - 7.2 6.7 30.3 10 6.2 9.5 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus RRM_1 PF00076.22 KFP03682.1 - 6.5e-17 61.1 0.0 5.6e-06 26.1 0.0 3.4 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFP03682.1 - 0.0017 18.3 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif DPRP PF04244.13 KFP03682.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein Mob1_phocein PF03637.17 KFP03683.1 - 4.6e-84 280.6 0.2 5.5e-84 280.3 0.2 1.1 1 0 0 1 1 1 1 Mob1/phocein family dNK PF01712.19 KFP03684.1 - 4.9e-73 245.3 0.2 5.5e-73 245.2 0.2 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_28 PF13521.6 KFP03684.1 - 0.00037 20.8 0.1 0.001 19.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFP03684.1 - 0.00055 20.5 0.1 0.0063 17.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFP03684.1 - 0.0028 17.8 0.0 0.01 16.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KFP03684.1 - 0.0061 16.3 0.2 0.035 13.8 0.1 2.1 2 0 0 2 2 2 1 Thymidylate kinase DUF5066 PF16728.5 KFP03684.1 - 0.034 13.5 0.1 0.049 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5066) AAA_17 PF13207.6 KFP03684.1 - 0.095 13.1 0.1 0.28 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain HCO3_cotransp PF00955.21 KFP03685.1 - 7.1e-240 797.1 7.1 8.9e-240 796.8 7.1 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 KFP03685.1 - 2e-73 247.5 7.4 1.7e-68 231.4 2.2 3.2 1 1 1 2 2 2 2 Band 3 cytoplasmic domain PTS_EIIA_2 PF00359.22 KFP03685.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Serum_albumin PF00273.20 KFP03686.1 - 1.1e-70 236.9 14.0 2.6e-33 115.3 1.4 3.4 3 1 0 3 3 3 3 Serum albumin family VitD-bind_III PF09164.10 KFP03686.1 - 1.8e-28 98.3 25.5 5.1e-28 96.9 1.1 6.1 5 1 1 6 6 6 4 Vitamin D binding protein, domain III 7tm_1 PF00001.21 KFP03687.1 - 2.1e-57 194.5 12.3 3.1e-57 193.9 12.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP03687.1 - 1.7e-08 34.1 13.2 2.4e-07 30.4 13.2 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP03687.1 - 6.5e-06 26.1 8.9 1.2e-05 25.3 8.9 1.3 1 0 0 1 1 1 1 Olfactory receptor 60KD_IMP PF02096.20 KFP03688.1 - 3.6e-15 56.3 0.0 6.7e-15 55.4 0.0 1.4 1 1 0 1 1 1 1 60Kd inner membrane protein HlyC PF02794.16 KFP03688.1 - 0.045 13.6 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 RTX toxin acyltransferase family Ank_2 PF12796.7 KFP03689.1 - 2.5e-152 495.8 33.8 1.5e-19 70.3 0.7 12.4 3 3 9 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP03689.1 - 8.8e-126 408.8 17.4 1.9e-12 47.4 0.0 16.8 8 4 10 19 19 19 18 Ankyrin repeats (many copies) Ank PF00023.30 KFP03689.1 - 8.1e-116 373.9 54.9 5.4e-08 32.9 0.0 24.9 25 0 0 25 25 25 21 Ankyrin repeat Ank_3 PF13606.6 KFP03689.1 - 3.3e-106 334.3 32.4 7.3e-05 22.9 0.0 25.2 25 0 0 25 25 25 23 Ankyrin repeat Ank_5 PF13857.6 KFP03689.1 - 6.6e-97 316.3 43.2 2.3e-10 40.5 0.0 20.2 7 4 14 21 21 21 21 Ankyrin repeats (many copies) KH_1 PF00013.29 KFP03689.1 - 2.6e-15 56.0 2.9 7.8e-15 54.5 2.9 1.9 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 KFP03689.1 - 0.074 12.9 0.0 0.32 10.9 0.0 2.1 1 0 0 1 1 1 0 KH domain Serum_albumin PF00273.20 KFP03690.1 - 3.7e-155 512.1 35.6 4e-57 192.8 9.7 3.1 3 0 0 3 3 3 3 Serum albumin family CYTL1 PF15153.6 KFP03690.1 - 0.0092 15.9 0.2 0.0092 15.9 0.2 2.6 3 0 0 3 3 3 1 Cytokine-like protein 1 VitD-bind_III PF09164.10 KFP03690.1 - 0.1 12.6 23.6 1 9.4 0.1 6.3 7 1 0 7 7 7 0 Vitamin D binding protein, domain III Serum_albumin PF00273.20 KFP03691.1 - 5e-149 492.1 38.4 6.5e-57 192.1 13.1 3.1 3 0 0 3 3 3 3 Serum albumin family VitD-bind_III PF09164.10 KFP03691.1 - 0.0017 18.3 16.8 0.0035 17.3 1.0 5.0 5 0 0 5 5 5 2 Vitamin D binding protein, domain III ThiP_synth PF10120.9 KFP03691.1 - 0.077 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Thiamine-phosphate synthase RA PF00788.23 KFP03692.1 - 6.3e-13 49.2 0.0 1.4e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Nore1-SARAH PF16517.5 KFP03692.1 - 2.6e-10 40.0 4.6 2.6e-10 40.0 4.6 2.1 2 0 0 2 2 2 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Ras_bdg_2 PF14847.6 KFP03692.1 - 0.0057 17.0 0.1 0.028 14.8 0.0 2.0 1 1 1 2 2 2 1 Ras-binding domain of Byr2 RecO_C PF02565.15 KFP03692.1 - 0.07 12.9 0.6 0.36 10.6 0.0 2.4 2 1 1 3 3 3 0 Recombination protein O C terminal YusW PF14039.6 KFP03692.1 - 0.12 12.9 1.6 0.31 11.6 0.0 2.2 3 0 0 3 3 3 0 YusW-like protein TUG-UBL1 PF11470.8 KFP03692.1 - 0.14 12.4 0.3 0.39 11.0 0.0 1.9 2 0 0 2 2 2 0 TUG ubiquitin-like domain IL8 PF00048.20 KFP03693.1 - 2.3e-16 59.7 0.1 2.7e-16 59.5 0.1 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like IL8 PF00048.20 KFP03694.1 - 8.7e-18 64.2 0.5 1e-17 64.0 0.5 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like bPH_6 PF10756.9 KFP03694.1 - 0.053 13.6 0.0 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial PH domain THF_DHG_CYH_C PF02882.19 KFP03695.1 - 1.1e-61 206.8 4.1 1.5e-61 206.4 4.1 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KFP03695.1 - 1.9e-38 131.3 0.1 2.7e-38 130.8 0.1 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AlaDh_PNT_C PF01262.21 KFP03695.1 - 0.026 13.8 0.1 0.043 13.1 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain EGF PF00008.27 KFP03696.1 - 0.04 14.2 3.4 0.086 13.2 3.4 1.6 1 0 0 1 1 1 0 EGF-like domain Rad60-SLD_2 PF13881.6 KFP03696.1 - 0.091 12.9 0.1 0.14 12.3 0.1 1.2 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF4514 PF14986.6 KFP03696.1 - 0.12 12.4 0.5 0.24 11.4 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) SKG6 PF08693.10 KFP03696.1 - 0.69 9.4 5.0 1.7 8.1 5.0 1.7 1 1 0 1 1 1 0 Transmembrane alpha-helix domain EGF PF00008.27 KFP03697.1 - 8.8e-05 22.7 3.4 0.00017 21.8 3.4 1.5 1 0 0 1 1 1 1 EGF-like domain CD34_antigen PF06365.12 KFP03697.1 - 0.0059 16.2 0.8 0.0059 16.2 0.8 1.3 1 1 0 1 1 1 1 CD34/Podocalyxin family Oxidored_q2 PF00420.24 KFP03697.1 - 0.044 13.4 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L EGF_2 PF07974.13 KFP03697.1 - 0.13 12.7 3.2 0.4 11.1 3.2 1.9 1 1 0 1 1 1 0 EGF-like domain InaF-motif PF15018.6 KFP03697.1 - 0.95 9.4 6.1 1.6 8.7 6.1 1.3 1 0 0 1 1 1 0 TRP-interacting helix EGF PF00008.27 KFP03698.1 - 0.00089 19.5 3.1 0.0016 18.7 3.1 1.4 1 0 0 1 1 1 1 EGF-like domain Ycf70 PF17382.2 KFP03698.1 - 0.0014 19.0 0.9 0.0071 16.7 0.1 2.0 2 0 0 2 2 2 1 Uncharacterized Ycf70-like PRIMA1 PF16101.5 KFP03698.1 - 0.02 15.0 0.1 0.043 13.9 0.1 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 FtsL PF04999.13 KFP03698.1 - 0.03 14.3 0.2 0.047 13.7 0.2 1.3 1 0 0 1 1 1 0 Cell division protein FtsL DUF3377 PF11857.8 KFP03698.1 - 0.035 14.0 0.3 0.079 12.9 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) TMEM154 PF15102.6 KFP03698.1 - 0.038 13.9 1.1 0.054 13.4 0.1 1.7 2 0 0 2 2 2 0 TMEM154 protein family ECSCR PF15820.5 KFP03698.1 - 0.041 13.7 0.4 0.041 13.7 0.4 1.8 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator Protocadherin PF08374.11 KFP03698.1 - 0.52 10.3 3.4 0.77 9.7 0.1 2.0 2 0 0 2 2 2 0 Protocadherin EphA2_TM PF14575.6 KFP03698.1 - 2.3 9.2 4.7 0.67 10.9 0.2 2.1 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Uso1_p115_head PF04869.14 KFP03699.1 - 9.2e-52 176.1 0.2 9.2e-52 176.1 0.2 3.1 3 1 0 3 3 3 1 Uso1 / p115 like vesicle tethering protein, head region Arm_vescicular PF18770.1 KFP03699.1 - 7.1e-23 80.3 2.4 7.1e-23 80.3 2.4 3.1 2 0 0 2 2 2 1 Armadillo tether-repeat of vescicular transport factor Uso1_p115_C PF04871.13 KFP03699.1 - 1.2e-10 41.9 26.2 1.2e-10 41.9 26.2 4.4 2 1 4 6 6 6 1 Uso1 / p115 like vesicle tethering protein, C terminal region TMF_TATA_bd PF12325.8 KFP03699.1 - 0.0011 19.2 13.9 0.0011 19.2 13.9 4.8 3 1 2 5 5 5 2 TATA element modulatory factor 1 TATA binding DUF812 PF05667.11 KFP03699.1 - 0.24 10.2 37.1 0.019 13.9 24.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF812) VPS11_C PF12451.8 KFP03699.1 - 1.5 9.1 7.2 0.61 10.4 0.3 3.7 2 1 1 3 3 3 0 Vacuolar protein sorting protein 11 C terminal Surfac_D-trimer PF09006.11 KFP03699.1 - 2 8.4 3.8 27 4.8 0.7 3.5 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation LRRFIP PF09738.9 KFP03699.1 - 2.8 7.3 39.9 5 6.5 21.4 3.1 1 1 2 3 3 3 0 LRRFIP family HIP1_clath_bdg PF16515.5 KFP03699.1 - 4.7 7.9 48.1 0.07 13.7 11.1 4.8 3 1 1 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 KFP03699.1 - 9.2 5.0 53.0 1.1 8.0 15.9 3.7 2 1 1 3 3 3 0 Spc7 kinetochore protein NTF2 PF02136.20 KFP03700.1 - 3e-33 114.9 0.1 5.1e-33 114.2 0.1 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KFP03700.1 - 3.8e-14 52.3 0.1 8.5e-14 51.1 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP03700.1 - 8.6e-06 25.8 0.0 2.1e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif eIF3_subunit PF08597.10 KFP03700.1 - 2.9 7.8 11.8 5.2 6.9 11.8 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Pkinase PF00069.25 KFP03701.1 - 1.5e-42 145.8 0.4 4.2e-42 144.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP03701.1 - 3.2e-24 85.6 0.0 3.2e-24 85.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP03701.1 - 1.8e-08 34.0 0.9 1.2e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFP03701.1 - 0.0023 17.0 0.1 0.0023 17.0 0.1 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KFP03701.1 - 0.0036 16.1 0.1 0.0098 14.7 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFP03701.1 - 0.023 14.6 0.1 0.023 14.6 0.1 2.7 2 2 1 3 3 3 0 Phosphotransferase enzyme family BMP2K_C PF15282.6 KFP03702.1 - 1.1e-113 379.4 16.9 5.2e-112 373.9 9.6 2.4 2 1 0 2 2 2 2 BMP-2-inducible protein kinase C-terminus HlyIII PF03006.20 KFP03703.1 - 4.3e-49 167.3 24.4 5.2e-49 167.0 24.4 1.0 1 0 0 1 1 1 1 Haemolysin-III related Presenilin PF01080.17 KFP03703.1 - 1 8.0 9.9 7.7 5.2 0.0 2.4 2 1 0 2 2 2 0 Presenilin Ant_C PF05586.11 KFP03704.1 - 5.4e-42 142.3 0.6 5.4e-42 142.3 0.6 1.8 2 0 0 2 2 2 1 Anthrax receptor C-terminus region VWA PF00092.28 KFP03705.1 - 9.4e-10 39.0 0.1 1e-09 38.9 0.1 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFP03705.1 - 0.0019 18.8 0.0 0.0035 18.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain FGF PF00167.18 KFP03707.1 - 1.2e-31 109.4 0.1 1.3e-31 109.3 0.1 1.0 1 0 0 1 1 1 1 Fibroblast growth factor DUF4464 PF14713.6 KFP03708.1 - 3e-75 252.6 0.0 3.3e-75 252.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) SHOCT PF09851.9 KFP03708.1 - 0.19 11.5 1.7 0.5 10.2 1.7 1.7 1 0 0 1 1 1 0 Short C-terminal domain TGF_beta PF00019.20 KFP03709.1 - 1.9e-11 44.8 0.1 1.9e-11 44.8 0.1 2.2 3 0 0 3 3 3 1 Transforming growth factor beta like domain Arc_C PF18162.1 KFP03710.1 - 7.3e-47 157.2 1.4 2e-46 155.8 1.4 1.8 1 0 0 1 1 1 1 Arc C-lobe Retrotrans_gag PF03732.17 KFP03710.1 - 0.0012 19.1 2.1 0.0021 18.3 0.5 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein DUF842 PF05811.13 KFP03710.1 - 0.0089 15.7 0.3 0.04 13.6 0.3 2.0 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF842) DUF2120 PF09893.9 KFP03710.1 - 0.01 16.0 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) THOC7 PF05615.13 KFP03710.1 - 0.013 15.8 0.4 0.023 15.0 0.4 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 KxDL PF10241.9 KFP03710.1 - 0.017 15.4 1.6 3.5 8.0 0.1 3.0 4 0 0 4 4 4 0 Uncharacterized conserved protein FH2 PF02181.23 KFP03710.1 - 0.034 13.3 0.5 0.067 12.3 0.5 1.4 1 0 0 1 1 1 0 Formin Homology 2 Domain ThiD2 PF17792.1 KFP03710.1 - 0.15 12.6 1.1 0.31 11.5 1.1 1.5 1 0 0 1 1 1 0 ThiD2 family SYCE1 PF15233.6 KFP03710.1 - 0.24 11.4 6.0 0.61 10.1 0.2 2.8 2 1 0 2 2 2 0 Synaptonemal complex central element protein 1 DDE_Tnp_ISL3 PF01610.17 KFP03710.1 - 0.44 10.2 6.2 9.7 5.8 2.5 2.6 3 0 0 3 3 3 0 Transposase UPAR_LY6 PF00021.21 KFP03713.1 - 4.4e-07 30.5 17.8 5.4e-07 30.2 17.8 1.1 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Toxin_TOLIP PF00087.21 KFP03713.1 - 1.1e-06 28.8 15.3 1.3e-06 28.5 15.3 1.1 1 0 0 1 1 1 1 Snake toxin and toxin-like protein DUF4345 PF14248.6 KFP03713.1 - 0.075 12.9 0.0 0.096 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4345) FlaC_arch PF05377.11 KFP03713.1 - 0.18 12.2 0.0 0.28 11.6 0.0 1.2 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) UPAR_LY6 PF00021.21 KFP03714.1 - 2.5e-05 24.9 10.5 3.1e-05 24.6 10.5 1.1 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Toxin_TOLIP PF00087.21 KFP03714.1 - 0.00023 21.4 10.8 0.00028 21.1 10.8 1.1 1 0 0 1 1 1 1 Snake toxin and toxin-like protein UPAR_LY6_2 PF16975.5 KFP03714.1 - 0.15 12.3 8.7 0.24 11.6 8.7 1.4 1 1 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 UPAR_LY6 PF00021.21 KFP03715.1 - 0.0057 17.3 0.6 0.0079 16.9 0.6 1.2 1 0 0 1 1 1 1 u-PAR/Ly-6 domain BAMBI PF06211.12 KFP03715.1 - 0.0076 16.5 0.6 0.0094 16.2 0.6 1.2 1 0 0 1 1 1 1 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Toxin_TOLIP PF00087.21 KFP03715.1 - 0.016 15.5 1.6 0.024 14.9 1.6 1.3 1 0 0 1 1 1 0 Snake toxin and toxin-like protein UPAR_LY6 PF00021.21 KFP03716.1 - 2.9e-15 56.7 9.9 3.5e-15 56.4 9.9 1.1 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Toxin_TOLIP PF00087.21 KFP03716.1 - 2.7e-10 40.3 9.1 3.3e-10 40.1 9.1 1.1 1 0 0 1 1 1 1 Snake toxin and toxin-like protein UPAR_LY6_2 PF16975.5 KFP03716.1 - 0.011 15.9 7.1 0.016 15.4 7.1 1.3 1 1 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 Toxin_TOLIP PF00087.21 KFP03717.1 - 7.3e-12 45.4 16.9 9.6e-12 45.0 16.9 1.2 1 0 0 1 1 1 1 Snake toxin and toxin-like protein UPAR_LY6 PF00021.21 KFP03717.1 - 7.9e-10 39.3 17.2 1e-09 39.0 17.2 1.1 1 0 0 1 1 1 1 u-PAR/Ly-6 domain UPAR_LY6_2 PF16975.5 KFP03717.1 - 5.2e-05 23.4 15.3 0.00013 22.2 15.3 1.6 1 1 0 1 1 1 1 Ly6/PLAUR domain-containing protein 6, Lypd6 DUF1075 PF06388.11 KFP03717.1 - 0.064 13.3 1.3 0.1 12.7 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1075) Toxin_TOLIP PF00087.21 KFP03718.1 - 1.7e-10 41.0 18.0 2.2e-10 40.6 18.0 1.2 1 0 0 1 1 1 1 Snake toxin and toxin-like protein UPAR_LY6 PF00021.21 KFP03718.1 - 1.1e-08 35.6 17.5 1.4e-08 35.3 17.5 1.1 1 0 0 1 1 1 1 u-PAR/Ly-6 domain UPAR_LY6 PF00021.21 KFP03719.1 - 4.2e-09 37.0 14.5 5e-09 36.7 14.5 1.1 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Toxin_TOLIP PF00087.21 KFP03719.1 - 2.9e-07 30.6 16.3 4.2e-07 30.1 16.3 1.3 1 0 0 1 1 1 1 Snake toxin and toxin-like protein Topoisom_I_N PF02919.15 KFP03720.1 - 2.6e-99 331.0 6.0 2.6e-99 331.0 6.0 4.3 4 1 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 KFP03720.1 - 5.8e-92 307.1 8.5 5.8e-92 307.1 8.5 1.7 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 KFP03720.1 - 1.4e-33 114.6 0.1 1.4e-33 114.6 0.1 2.4 2 0 0 2 2 2 1 C-terminal topoisomerase domain DUF641 PF04859.12 KFP03720.1 - 1.8 8.9 18.2 0.028 14.7 5.2 3.5 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) BRO1 PF03097.18 KFP03721.1 - 1.8e-95 320.0 0.2 2.7e-95 319.5 0.2 1.2 1 0 0 1 1 1 1 BRO1-like domain HR1 PF02185.16 KFP03721.1 - 2.3e-20 72.4 4.8 5.5e-20 71.3 4.8 1.7 1 0 0 1 1 1 1 Hr1 repeat PDZ PF00595.24 KFP03721.1 - 5.7e-14 52.2 0.0 1.1e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP03721.1 - 1.8e-12 46.9 0.1 3.7e-12 45.9 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP03721.1 - 2.7e-05 24.4 0.0 8.5e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 PDZ domain Uds1 PF15456.6 KFP03721.1 - 0.027 14.6 3.7 0.07 13.3 3.7 1.6 1 0 0 1 1 1 0 Up-regulated During Septation Tricorn_PDZ PF14685.6 KFP03721.1 - 0.17 11.8 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain RVT_1 PF00078.27 KFP03723.1 - 4.8e-10 39.3 0.0 6.5e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AA_kinase PF00696.28 KFP03724.1 - 8.2e-36 123.8 0.1 1.7e-35 122.8 0.1 1.5 1 0 0 1 1 1 1 Amino acid kinase family Aldedh PF00171.22 KFP03724.1 - 2.5e-10 39.5 0.3 3.5e-07 29.1 0.2 2.7 2 1 0 2 2 2 2 Aldehyde dehydrogenase family 7tm_1 PF00001.21 KFP03725.1 - 5.4e-45 153.8 14.4 6.5e-45 153.5 14.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP03725.1 - 8e-08 32.0 13.0 9.4e-08 31.7 13.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 KFP03725.1 - 4.1e-07 29.7 7.7 4.1e-07 29.7 7.7 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.9 KFP03725.1 - 8.9e-06 25.2 13.7 0.0001 21.7 13.4 2.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 KFP03725.1 - 0.00045 20.0 13.0 0.0033 17.2 13.0 1.9 1 1 0 1 1 1 1 Olfactory receptor Homeodomain PF00046.29 KFP03726.1 - 3e-22 78.2 1.1 4.9e-22 77.5 1.1 1.3 1 0 0 1 1 1 1 Homeodomain PKK PF12474.8 KFP03726.1 - 0.0012 19.0 1.9 0.0024 18.0 1.9 1.4 1 0 0 1 1 1 1 Polo kinase kinase Homez PF11569.8 KFP03726.1 - 0.021 14.3 0.1 0.057 12.9 0.0 1.7 1 1 1 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 KFP03726.1 - 0.045 13.6 0.0 0.099 12.6 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain Exo_endo_phos PF03372.23 KFP03727.1 - 1.7e-17 63.7 0.0 2.2e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family OLF PF02191.16 KFP03727.1 - 0.047 13.2 1.3 0.084 12.4 1.3 1.4 1 0 0 1 1 1 0 Olfactomedin-like domain Pkinase PF00069.25 KFP03728.1 - 1.1e-62 211.8 0.6 1.4e-62 211.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP03728.1 - 6.7e-35 120.6 0.1 9.8e-35 120.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP03728.1 - 1.1e-09 38.0 0.0 1.5e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP03728.1 - 0.00035 19.5 0.4 0.001 18.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KFP03728.1 - 0.0062 15.9 0.3 0.0062 15.9 0.3 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP03728.1 - 0.0099 15.8 0.1 0.019 14.9 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family v110 PF01639.17 KFP03728.1 - 0.13 12.1 1.1 1 9.3 0.1 2.2 2 0 0 2 2 2 0 Viral family 110 JAKMIP_CC3 PF16034.5 KFP03729.1 - 3.1e-84 281.9 21.3 3.1e-84 281.9 21.3 7.1 4 2 4 8 8 8 1 JAKMIP CC3 domain Coat_F PF07875.12 KFP03729.1 - 0.017 15.3 0.5 0.1 12.9 0.5 2.4 1 0 0 1 1 1 0 Coat F domain HEPN_RES_NTD1 PF18870.1 KFP03729.1 - 8.2 6.6 8.4 1.2 9.4 1.4 2.9 2 1 0 2 2 2 0 HEPN/RES N-terminal domain 1 BNIP3 PF06553.12 KFP03730.1 - 2.5e-82 275.3 5.0 2.9e-82 275.1 5.0 1.0 1 0 0 1 1 1 1 BNIP3 SIR4_SID PF16991.5 KFP03730.1 - 0.054 13.5 1.0 0.082 13.0 1.0 1.2 1 0 0 1 1 1 0 Sir4 SID domain WD40 PF00400.32 KFP03731.1 - 1.3e-08 35.4 3.8 5.1 8.1 0.1 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP03731.1 - 0.00047 20.4 0.0 18 5.7 0.0 4.6 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Y_phosphatase2 PF03162.13 KFP03731.1 - 0.0032 17.0 0.3 0.21 11.2 0.0 2.4 2 0 0 2 2 2 2 Tyrosine phosphatase family FF PF01846.19 KFP03732.1 - 3.3e-20 72.0 11.7 4.3e-10 39.6 1.1 2.4 2 0 0 2 2 2 2 FF domain WW PF00397.26 KFP03732.1 - 2.8e-05 24.1 0.1 2.8e-05 24.1 0.1 1.9 2 0 0 2 2 2 1 WW domain DUF3835 PF12927.7 KFP03732.1 - 0.47 11.4 4.5 0.4 11.6 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) HEAT_EZ PF13513.6 KFP03733.1 - 1.7e-32 111.4 0.2 4.9e-12 46.1 0.0 9.8 8 2 1 9 9 9 3 HEAT-like repeat HEAT PF02985.22 KFP03733.1 - 4.8e-31 104.1 7.7 0.0056 16.8 0.0 11.5 11 0 0 11 11 11 7 HEAT repeat HEAT_2 PF13646.6 KFP03733.1 - 4.7e-20 71.8 0.0 4.6e-06 26.9 0.0 6.2 4 2 2 6 6 6 5 HEAT repeats IBN_N PF03810.19 KFP03733.1 - 2.7e-16 59.2 0.1 1.5e-15 56.8 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.23 KFP03733.1 - 6.2e-16 57.8 7.9 0.0058 16.6 0.0 7.9 9 0 0 9 9 8 3 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KFP03733.1 - 1.7e-15 57.4 0.5 0.00023 21.2 0.3 4.3 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KFP03733.1 - 4.3e-14 52.9 0.6 0.00063 20.3 0.2 6.3 4 2 3 7 7 7 5 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KFP03733.1 - 2.2e-08 33.2 3.7 0.032 12.8 0.3 4.6 2 2 1 4 4 4 3 Adaptin N terminal region UNC45-central PF11701.8 KFP03733.1 - 8.9e-05 22.5 3.6 0.007 16.3 0.2 4.1 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central Dopey_N PF04118.14 KFP03733.1 - 0.00027 20.2 1.5 0.001 18.3 0.1 2.5 2 1 0 2 2 2 1 Dopey, N-terminal CLASP_N PF12348.8 KFP03733.1 - 0.00052 19.6 0.4 2.5 7.6 0.0 4.3 3 1 0 3 3 3 1 CLASP N terminal MMS19_C PF12460.8 KFP03733.1 - 0.001 18.3 4.8 0.3 10.1 0.1 4.7 3 2 1 4 4 4 2 RNAPII transcription regulator C-terminal Xpo1 PF08389.12 KFP03733.1 - 0.0021 18.1 3.1 4.4 7.4 0.3 4.6 3 1 0 3 3 3 1 Exportin 1-like protein RTP1_C1 PF10363.9 KFP03733.1 - 0.0024 18.1 0.2 0.051 13.8 0.1 3.1 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF3689 PF12463.8 KFP03733.1 - 0.015 14.6 0.0 0.1 11.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3689) TAFH PF07531.14 KFP03733.1 - 0.054 13.6 3.1 8.3 6.6 0.0 4.6 5 1 1 6 6 6 0 NHR1 homology to TAF Tti2 PF10521.9 KFP03733.1 - 0.12 11.9 0.3 37 3.7 0.0 4.2 3 2 3 6 6 6 0 Tti2 family HSP20 PF00011.21 KFP03734.1 - 9e-17 61.1 0.0 1.2e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family YabP PF07873.11 KFP03734.1 - 0.023 14.5 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 YabP family PDZ_5 PF17817.1 KFP03734.1 - 0.088 13.1 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 PDZ domain SRRM_C PF15230.6 KFP03735.1 - 3e-28 98.2 27.9 3e-28 98.2 27.9 9.2 4 3 4 8 8 8 1 Serine/arginine repetitive matrix protein C-terminus Sds3 PF08598.11 KFP03736.1 - 4.3e-08 33.4 6.2 7.7e-08 32.6 5.1 1.9 2 0 0 2 2 2 1 Sds3-like EAP30 PF04157.16 KFP03736.1 - 0.023 14.0 0.6 0.034 13.4 0.6 1.4 1 0 0 1 1 1 0 EAP30/Vps36 family Retrotrans_gag PF03732.17 KFP03736.1 - 0.094 13.0 3.7 0.22 11.8 3.7 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein PBP PF01161.20 KFP03737.1 - 1.8e-17 63.9 0.0 2.2e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein OrfB_IS605 PF01385.19 KFP03738.1 - 0.064 13.5 2.7 0.083 13.1 2.7 1.2 1 0 0 1 1 1 0 Probable transposase Rootletin PF15035.6 KFP03738.1 - 0.085 12.9 6.7 0.11 12.6 6.7 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TRP PF06011.12 KFP03738.1 - 0.087 11.5 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF4407 PF14362.6 KFP03738.1 - 0.12 11.7 4.1 0.14 11.5 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ACCA PF03255.14 KFP03738.1 - 0.13 12.1 1.7 0.16 11.9 1.7 1.1 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ABC_tran_CTD PF16326.5 KFP03738.1 - 1.1 9.5 8.9 0.31 11.3 6.1 1.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain DEAD PF00270.29 KFP03739.1 - 3.4e-50 170.3 0.0 6.8e-50 169.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP03739.1 - 1.2e-24 86.8 0.0 8.2e-24 84.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KFP03739.1 - 7e-19 67.8 7.6 1.8e-18 66.5 7.6 1.8 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.15 KFP03739.1 - 2.7e-08 34.0 0.0 1.7e-07 31.4 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Ion_trans PF00520.31 KFP03740.1 - 9.8e-54 182.2 61.1 2.6e-27 95.6 29.8 2.3 2 0 0 2 2 2 2 Ion transport protein ECSCR PF15820.5 KFP03740.1 - 0.1 12.4 0.1 0.66 9.8 0.2 2.3 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator Pilin_N PF07790.11 KFP03740.1 - 0.14 13.1 0.2 1.1 10.2 0.2 2.3 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal SurA_N_2 PF13623.6 KFP03740.1 - 3.5 7.5 5.5 0.75 9.7 1.0 2.2 2 0 0 2 2 2 0 SurA N-terminal domain Na_Ca_ex PF01699.24 KFP03741.1 - 1.1e-45 155.3 46.2 5.4e-25 88.1 17.4 3.0 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Cyt_c_ox_IV PF12270.8 KFP03741.1 - 0.0088 16.2 0.0 0.0088 16.2 0.0 3.6 4 0 0 4 4 4 1 Cytochrome c oxidase subunit IV PRCH PF03967.13 KFP03741.1 - 0.06 13.6 0.1 0.06 13.6 0.1 2.7 2 1 1 3 3 3 0 Photosynthetic reaction centre, H-chain N-terminal region Phospholip_B PF04916.13 KFP03742.1 - 1e-165 552.4 0.0 1.1e-165 552.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase B PALP PF00291.25 KFP03743.1 - 5.5e-46 157.3 0.0 6.1e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GIDA PF01134.22 KFP03743.1 - 0.0089 15.1 0.2 0.013 14.6 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AIRC PF00731.20 KFP03743.1 - 0.012 15.1 0.1 0.017 14.7 0.1 1.2 1 0 0 1 1 1 0 AIR carboxylase AlaDh_PNT_C PF01262.21 KFP03743.1 - 0.055 12.8 0.0 0.067 12.5 0.0 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KFP03743.1 - 0.062 12.4 0.2 0.09 11.8 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain LIM PF00412.22 KFP03744.1 - 3.2e-27 94.5 22.1 8.6e-19 67.5 1.7 2.2 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 KFP03744.1 - 5.6e-10 38.9 0.1 1.1e-09 38.0 0.1 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP03744.1 - 0.16 11.9 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain RRM_1 PF00076.22 KFP03746.1 - 2.1e-79 261.3 2.5 8.3e-19 67.2 0.0 6.4 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP03746.1 - 6.7e-06 26.1 0.0 0.86 9.8 0.0 4.5 4 0 0 4 4 4 2 RNA recognition motif RRM_occluded PF16842.5 KFP03746.1 - 4.3e-05 23.3 0.0 4.5 7.2 0.0 4.1 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 KFP03746.1 - 0.0001 22.2 7.5 0.88 9.4 0.0 5.4 6 0 0 6 6 6 2 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 KFP03746.1 - 0.00021 21.3 0.7 1.5 8.8 0.0 4.7 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 KFP03746.1 - 0.0012 18.8 0.0 1.3 9.1 0.0 4.1 4 0 0 4 4 4 1 Limkain b1 RRM_3 PF08777.11 KFP03746.1 - 0.047 13.7 17.1 0.9 9.6 0.0 6.5 6 2 1 7 7 7 0 RNA binding motif DUF1838 PF08894.11 KFP03747.1 - 0.0091 15.7 7.2 5.8 6.6 0.1 3.6 1 1 3 4 4 4 4 Protein of unknown function (DUF1838) CTD PF12815.7 KFP03747.1 - 0.055 14.0 14.8 2.4 8.8 14.8 2.4 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF1838 PF08894.11 KFP03748.1 - 0.003 17.3 19.6 13 5.5 0.1 6.5 1 1 7 8 8 8 8 Protein of unknown function (DUF1838) CTD PF12815.7 KFP03748.1 - 0.026 15.1 27.6 1.8e+04 -3.8 27.6 3.2 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 T-box PF00907.22 KFP03749.1 - 9e-39 133.6 0.3 2.2e-31 109.5 0.0 2.6 3 0 0 3 3 3 2 T-box BatD PF13584.6 KFP03749.1 - 0.048 12.5 0.0 0.048 12.5 0.0 1.7 2 0 0 2 2 2 0 Oxygen tolerance TMEM154 PF15102.6 KFP03749.1 - 0.13 12.1 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 TMEM154 protein family T-box PF00907.22 KFP03750.1 - 2e-73 246.6 0.2 2.2e-73 246.4 0.2 1.0 1 0 0 1 1 1 1 T-box Med13_C PF06333.12 KFP03751.1 - 4.4e-118 394.3 0.5 4.4e-118 394.3 0.5 3.8 4 0 0 4 4 4 1 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 KFP03751.1 - 3.6e-99 331.5 0.6 2.7e-98 328.7 0.0 2.7 3 0 0 3 3 3 1 MID domain of medPIWI DUF2054 PF10218.9 KFP03752.1 - 1.3e-45 154.7 16.6 1.7e-45 154.3 16.6 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2054) APS-reductase_C PF12139.8 KFP03752.1 - 0.019 15.1 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 Adenosine-5'-phosphosulfate reductase beta subunit DUF3369 PF11849.8 KFP03752.1 - 0.084 13.1 0.1 0.18 12.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3369) F-box-like PF12937.7 KFP03754.1 - 3.2e-13 49.3 0.1 9.8e-13 47.8 0.1 1.9 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 KFP03754.1 - 5.2e-09 36.6 2.4 6.1 7.9 0.0 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat F-box PF00646.33 KFP03754.1 - 2.9e-08 33.4 0.0 9e-08 31.8 0.0 1.9 2 0 0 2 2 2 1 F-box domain BBS2_Mid PF14783.6 KFP03754.1 - 0.0035 17.4 0.0 0.061 13.4 0.0 2.4 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region EF-hand_7 PF13499.6 KFP03755.1 - 2.7e-11 43.8 11.0 1.2e-06 28.9 0.5 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFP03755.1 - 1.6e-08 33.5 0.2 1.4e-06 27.4 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KFP03755.1 - 6.3e-06 25.7 0.4 3.9e-05 23.3 0.1 2.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 KFP03755.1 - 7.8e-05 22.0 0.0 0.00024 20.4 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KFP03755.1 - 0.0078 16.0 2.4 0.17 11.8 0.6 2.6 2 0 0 2 2 2 1 EF-hand domain pair Caleosin PF05042.13 KFP03755.1 - 0.048 13.6 0.2 0.42 10.5 0.2 2.3 1 1 1 2 2 2 0 Caleosin related protein DUF4196 PF13846.6 KFP03755.1 - 0.051 13.8 0.1 0.088 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4196) Gb3_synth PF04572.12 KFP03755.1 - 0.056 13.6 0.0 0.083 13.1 0.0 1.2 1 0 0 1 1 1 0 Alpha 1,4-glycosyltransferase conserved region Phage_GP20 PF06810.11 KFP03755.1 - 0.13 12.1 0.2 0.29 10.9 0.2 1.6 1 1 1 2 2 2 0 Phage minor structural protein GP20 Transglut_core2 PF13369.6 KFP03756.1 - 1.4e-42 144.9 0.0 2.4e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily YccV-like PF08755.11 KFP03756.1 - 3.3e-29 101.3 0.5 5.3e-28 97.4 0.0 2.8 2 1 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Pkinase_Tyr PF07714.17 KFP03757.1 - 5.4e-46 157.0 0.0 7.1e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP03757.1 - 1.4e-40 139.4 0.0 1.9e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain C1_1 PF00130.22 KFP03757.1 - 1.7e-05 24.6 11.8 4.2e-05 23.3 11.8 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 KFP03757.1 - 0.00054 19.4 0.0 0.0013 18.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFP03757.1 - 0.023 14.3 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KFP03757.1 - 0.024 14.0 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING-like PF08746.11 KFP03757.1 - 0.058 13.7 6.9 0.15 12.4 6.9 1.7 1 0 0 1 1 1 0 RING-like domain FTA2 PF13095.6 KFP03757.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFP03757.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family C1_2 PF03107.16 KFP03757.1 - 6.7 7.1 11.6 0.78 10.1 6.5 2.1 2 0 0 2 2 2 0 C1 domain Rep_fac_C PF08542.11 KFP03758.1 - 6.2e-25 87.4 0.2 1.7e-24 86.0 0.1 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 KFP03758.1 - 9.3e-16 58.5 0.0 1.6e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KFP03758.1 - 4.4e-13 49.3 0.0 4.9e-11 42.7 0.0 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 KFP03758.1 - 2e-06 28.3 0.0 5.6e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KFP03758.1 - 8.1e-06 25.7 0.0 1.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFP03758.1 - 1.1e-05 25.7 0.1 0.025 14.8 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_assoc_2 PF16193.5 KFP03758.1 - 2.1e-05 24.8 0.0 4.7e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 KFP03758.1 - 2.1e-05 24.4 0.0 0.00037 20.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 KFP03758.1 - 0.00017 21.9 0.2 0.021 15.1 0.0 3.0 2 1 1 3 3 3 1 AAA domain ResIII PF04851.15 KFP03758.1 - 0.00023 21.2 0.0 0.068 13.2 0.0 2.3 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit DNA_pol3_delta PF06144.13 KFP03758.1 - 0.00032 20.5 0.0 0.0007 19.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_5 PF07728.14 KFP03758.1 - 0.00057 19.9 0.1 0.0034 17.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TniB PF05621.11 KFP03758.1 - 0.0011 18.4 0.0 0.023 14.1 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein DEAD PF00270.29 KFP03758.1 - 0.0015 18.4 0.1 0.039 13.7 0.0 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_14 PF13173.6 KFP03758.1 - 0.0015 18.6 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFP03758.1 - 0.0017 18.1 0.0 0.03 14.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 KFP03758.1 - 0.0033 16.9 0.3 0.17 11.3 0.0 2.7 2 1 0 3 3 3 1 PhoH-like protein RuvB_N PF05496.12 KFP03758.1 - 0.0042 16.8 0.0 0.01 15.6 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KFP03758.1 - 0.019 14.5 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KFP03758.1 - 0.027 14.2 0.1 0.19 11.4 0.1 2.1 1 1 0 1 1 1 0 IstB-like ATP binding protein Rad17 PF03215.15 KFP03758.1 - 0.029 14.3 0.1 0.28 11.1 0.0 2.5 2 1 0 3 3 3 0 Rad17 P-loop domain AAA_25 PF13481.6 KFP03758.1 - 0.031 13.9 0.0 0.46 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KFP03758.1 - 0.05 13.0 0.0 0.76 9.1 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Hydantoinase_B PF02538.14 KFP03758.1 - 0.072 11.5 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase AAA_3 PF07726.11 KFP03758.1 - 0.094 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SNF2_N PF00176.23 KFP03758.1 - 0.1 11.3 0.0 0.16 10.6 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain TIP49 PF06068.13 KFP03758.1 - 0.12 11.5 0.0 0.26 10.4 0.0 1.5 2 0 0 2 2 2 0 TIP49 P-loop domain Thioredoxin_6 PF13848.6 KFP03758.1 - 0.19 11.6 0.0 0.68 9.8 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin-like domain WD40 PF00400.32 KFP03759.1 - 3.7e-23 81.4 15.4 4.1e-07 30.6 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat SOCS_box PF07525.16 KFP03759.1 - 9.6e-09 35.5 0.6 1.8e-08 34.6 0.6 1.4 1 0 0 1 1 1 1 SOCS box ANAPC4_WD40 PF12894.7 KFP03759.1 - 4.2e-05 23.8 0.0 2.2 8.6 0.0 4.5 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP03759.1 - 0.049 12.3 0.2 0.17 10.5 0.1 1.8 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFP03759.1 - 0.11 11.5 0.0 30 3.4 0.0 3.3 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KFP03759.1 - 4 7.5 6.9 4.4 7.4 0.4 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DTC PF18102.1 KFP03760.1 - 1.7e-60 203.0 0.0 2.7e-60 202.3 0.0 1.3 1 0 0 1 1 1 1 Deltex C-terminal domain zf-C3HC4 PF00097.25 KFP03760.1 - 5.9e-06 26.1 0.7 1.5e-05 24.7 0.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP03760.1 - 1.2e-05 25.5 0.9 6.8e-05 23.1 0.9 2.2 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFP03760.1 - 4.1e-05 23.8 2.2 0.00013 22.2 0.8 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFP03760.1 - 0.00012 22.1 0.0 0.00037 20.5 0.0 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP03760.1 - 0.00043 20.2 0.7 0.001 19.0 0.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KFP03760.1 - 0.001 18.8 1.2 0.63 9.8 0.1 2.6 2 0 0 2 2 2 2 RING-like zinc finger zf-ANAPC11 PF12861.7 KFP03760.1 - 0.0022 18.0 1.7 0.0043 17.1 0.7 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-LITAF-like PF10601.9 KFP03760.1 - 0.025 14.8 0.7 0.025 14.8 0.7 2.2 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain zf-UDP PF14569.6 KFP03760.1 - 0.035 14.2 0.9 0.067 13.3 0.1 1.8 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.6 KFP03760.1 - 0.063 13.1 5.7 1.2 9.0 1.8 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KFP03760.1 - 0.12 12.3 0.3 0.12 12.3 0.3 1.9 2 0 0 2 2 2 0 PHD-finger zf-C3HC4_4 PF15227.6 KFP03760.1 - 0.83 9.9 3.5 0.58 10.4 0.7 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING ADK_lid PF05191.14 KFP03760.1 - 1.5 8.8 8.7 9 6.4 0.1 4.0 4 0 0 4 4 4 0 Adenylate kinase, active site lid zf-RanBP PF00641.18 KFP03761.1 - 6.9e-13 47.7 7.4 1e-12 47.1 7.4 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 KFP03761.1 - 1.9e-10 40.4 0.1 7.5e-10 38.5 0.1 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Adaptin_N PF01602.20 KFP03762.1 - 1.1e-164 548.9 15.1 1.4e-164 548.5 15.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KFP03762.1 - 9.1e-69 230.6 12.7 1.2e-66 223.7 1.3 3.6 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 KFP03762.1 - 1.3e-37 128.3 0.1 3.5e-37 126.9 0.1 1.8 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 KFP03762.1 - 9.2e-23 80.4 3.9 1.4e-08 35.0 0.0 6.1 3 2 4 7 7 7 6 HEAT repeats HEAT PF02985.22 KFP03762.1 - 2.8e-13 48.9 8.6 0.008 16.3 0.1 7.4 7 0 0 7 7 7 3 HEAT repeat Alpha_adaptinC2 PF02883.20 KFP03762.1 - 1.2e-09 38.5 0.3 1.2e-09 38.5 0.3 1.9 2 0 0 2 2 1 1 Adaptin C-terminal domain Cnd3 PF12719.7 KFP03762.1 - 1.8e-09 37.2 4.2 1.1e-05 24.8 0.3 2.7 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 KFP03762.1 - 6.4e-07 29.2 4.6 0.02 15.0 0.0 5.6 6 0 0 6 6 5 2 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KFP03762.1 - 1.6e-05 25.0 6.9 0.047 13.9 0.0 5.2 2 2 1 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KFP03762.1 - 8.9e-05 22.2 2.0 0.75 9.3 0.1 4.1 2 2 1 3 3 3 2 CLASP N terminal Arm_2 PF04826.13 KFP03762.1 - 0.0072 15.8 0.2 0.028 13.9 0.0 2.1 2 0 0 2 2 2 1 Armadillo-like UNC45-central PF11701.8 KFP03762.1 - 0.011 15.7 0.5 1.4 8.8 0.0 3.5 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central Alpha_adaptin_C PF02296.16 KFP03762.1 - 0.021 15.0 0.2 0.099 12.8 0.0 2.3 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain HEAT_EZ PF13513.6 KFP03762.1 - 0.049 14.1 7.6 12 6.5 0.0 6.0 7 0 0 7 7 7 0 HEAT-like repeat Cohesin_HEAT PF12765.7 KFP03762.1 - 0.089 13.1 0.1 84 3.6 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Mo25 PF08569.11 KFP03762.1 - 0.37 10.1 6.4 0.19 11.1 0.3 2.6 2 1 0 2 2 2 0 Mo25-like Sec7_N PF12783.7 KFP03762.1 - 0.69 9.8 7.6 0.26 11.2 0.4 3.5 3 1 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Filament PF00038.21 KFP03763.1 - 8.5e-38 130.7 15.7 8.5e-38 130.7 15.7 2.5 3 0 0 3 3 3 1 Intermediate filament protein FmiP_Thoc5 PF09766.9 KFP03764.1 - 3.7e-125 418.0 6.3 5.4e-125 417.5 6.3 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 DUF4611 PF15387.6 KFP03764.1 - 0.78 10.0 3.9 2.7 8.3 0.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) NIPSNAP PF07978.13 KFP03765.1 - 4.4e-11 42.9 1.2 1e-06 28.9 0.2 2.9 2 1 0 2 2 2 2 NIPSNAP SLC12 PF03522.15 KFP03766.1 - 1.3e-156 521.9 2.1 1.6e-103 347.0 0.6 2.1 1 1 1 2 2 2 2 Solute carrier family 12 AA_permease PF00324.21 KFP03766.1 - 1.2e-150 502.3 37.8 1.4e-150 502.0 37.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFP03766.1 - 1.9e-18 66.5 44.3 3.1e-18 65.8 44.3 1.2 1 0 0 1 1 1 1 Amino acid permease NTPase_I-T PF01931.18 KFP03767.1 - 5.6e-10 39.3 0.0 1.7e-09 37.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function DUF84 Laminin_EGF PF00053.24 KFP03768.1 - 3e-46 155.3 327.0 0.0019 18.3 16.0 18.2 5 3 13 18 18 18 16 Laminin EGF domain hEGF PF12661.7 KFP03768.1 - 2.5e-27 94.5 257.4 1.8e-05 25.2 5.3 22.4 21 2 1 22 22 22 16 Human growth factor-like EGF EGF_2 PF07974.13 KFP03768.1 - 2e-11 44.0 380.3 0.0007 19.9 17.3 25.9 21 9 4 25 25 25 13 EGF-like domain EGF PF00008.27 KFP03768.1 - 0.00013 22.2 328.1 0.0091 16.3 13.4 23.3 24 1 0 24 24 24 12 EGF-like domain Baculo_11_kDa PF06143.11 KFP03768.1 - 0.024 14.2 0.5 0.041 13.5 0.5 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family Syndecan PF01034.20 KFP03768.1 - 0.024 14.5 2.0 0.045 13.7 2.0 1.4 1 0 0 1 1 1 0 Syndecan domain Orf78 PF06024.12 KFP03768.1 - 0.24 11.7 0.2 0.4 11.0 0.2 1.2 1 0 0 1 1 1 0 Orf78 (ac78) DUF202 PF02656.15 KFP03768.1 - 0.32 11.5 0.9 0.52 10.8 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF202) RVT_1 PF00078.27 KFP03769.1 - 0.0058 16.2 0.0 0.0087 15.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF836 PF05768.14 KFP03771.1 - 1.8e-10 41.1 0.1 2.2e-10 40.8 0.1 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KFP03771.1 - 0.015 15.5 0.1 0.022 14.9 0.1 1.5 1 1 0 1 1 1 0 Glutaredoxin RINGv PF12906.7 KFP03772.1 - 3e-15 56.0 9.8 3e-15 56.0 9.8 1.9 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.6 KFP03772.1 - 0.0017 18.6 9.7 0.0017 18.6 9.7 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KFP03772.1 - 0.091 12.7 5.9 0.42 10.5 5.9 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vpu PF00558.19 KFP03772.1 - 0.12 12.2 0.4 0.19 11.5 0.4 1.3 1 0 0 1 1 1 0 Vpu protein Baculo_IE-1 PF05290.11 KFP03772.1 - 0.13 12.2 1.8 0.23 11.4 1.8 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) FANCL_C PF11793.8 KFP03772.1 - 6.2 7.1 10.5 0.87 9.8 4.5 2.5 2 1 1 3 3 3 0 FANCL C-terminal domain RNA_GG_bind PF10258.9 KFP03773.1 - 8.4e-33 112.3 2.9 1.2e-32 111.8 0.2 2.5 3 0 0 3 3 3 1 PHAX RNA-binding domain FoP_duplication PF13865.6 KFP03773.1 - 0.00078 20.0 0.8 0.0024 18.4 0.8 1.9 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 zf-C2H2 PF00096.26 KFP03774.1 - 3.2e-17 61.9 21.7 1e-05 25.7 2.8 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP03774.1 - 5.9e-11 42.3 11.1 1.2e-06 28.7 2.9 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP03774.1 - 4.1e-09 36.5 19.8 0.0055 17.4 2.5 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFP03774.1 - 0.028 14.8 4.4 1.8 9.1 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KFP03774.1 - 0.031 14.9 6.2 2.6 8.7 1.7 2.7 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KFP03774.1 - 0.083 13.2 4.0 0.16 12.3 4.0 1.5 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2HE PF16278.5 KFP03774.1 - 0.095 13.2 6.4 2.5 8.6 2.3 2.3 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger DUF3850 PF12961.7 KFP03774.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) zf-C2H2_11 PF16622.5 KFP03774.1 - 0.4 10.5 9.3 11 5.9 1.0 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFP03774.1 - 1.5 9.2 7.0 5.3 7.5 0.4 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding XPC-binding PF09280.11 KFP03775.1 - 4e-26 90.5 19.0 7e-26 89.7 19.0 1.4 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 KFP03775.1 - 4.4e-26 90.4 2.5 9.8e-14 50.9 0.3 2.5 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 KFP03775.1 - 1.7e-13 50.1 0.2 4.2e-13 48.8 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family UBA_3 PF09288.10 KFP03775.1 - 0.00041 20.1 0.0 0.011 15.6 0.0 2.3 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.6 KFP03775.1 - 0.002 18.2 0.0 0.0037 17.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KFP03775.1 - 0.034 14.7 0.0 0.072 13.7 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF1296 PF06972.11 KFP03775.1 - 0.098 12.8 0.0 2.8 8.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) DUF1421 PF07223.11 KFP03775.1 - 0.1 12.5 0.0 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 UBA-like domain (DUF1421) UBA_2 PF08587.11 KFP03775.1 - 0.11 12.6 0.1 0.28 11.3 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) Rad60-SLD PF11976.8 KFP03775.1 - 0.18 11.7 0.1 0.33 10.8 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DEC-1_N PF04625.13 KFP03775.1 - 0.91 8.5 19.4 0.67 8.9 9.6 2.1 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region STI1 PF17830.1 KFP03775.1 - 1.8 8.6 6.4 11 6.0 6.3 2.3 1 1 0 1 1 1 0 STI1 domain INTAP PF16617.5 KFP03775.1 - 3 8.2 13.6 0.13 12.6 2.3 3.0 3 0 0 3 3 3 0 Intersectin and clathrin adaptor AP2 binding region zf-H2C2_5 PF13909.6 KFP03776.1 - 3.2e-16 58.8 28.3 1.2e-07 31.3 1.8 28.7 30 0 0 30 30 30 16 C2H2-type zinc-finger domain zf_C2H2_ZHX PF18387.1 KFP03776.1 - 1.4e-09 37.4 157.1 0.0082 15.8 1.4 27.0 26 3 4 30 30 30 14 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 KFP03776.1 - 0.0073 16.7 6.6 0.0073 16.7 6.6 28.7 34 0 0 34 34 34 10 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP03776.1 - 0.012 16.4 0.2 0.012 16.4 0.2 34.4 35 0 0 35 35 35 0 C2H2-type zinc finger DUF4367 PF14285.6 KFP03776.1 - 0.052 14.0 2.8 0.19 12.1 2.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) zf-C2H2 PF00096.26 KFP03776.1 - 0.054 14.0 0.1 0.054 14.0 0.1 32.4 35 0 0 35 35 35 0 Zinc finger, C2H2 type DDRGK PF09756.9 KFP03777.1 - 8.7 5.9 14.7 9.5 5.8 14.7 1.0 1 0 0 1 1 1 0 DDRGK domain TRIC PF05197.13 KFP03778.1 - 7.5e-83 276.8 5.8 8.8e-83 276.6 5.8 1.0 1 0 0 1 1 1 1 TRIC channel UPF0126 PF03458.13 KFP03778.1 - 0.012 15.5 7.4 0.11 12.3 0.2 2.7 2 1 0 2 2 2 0 UPF0126 domain HLH PF00010.26 KFP03779.1 - 1.8e-17 63.0 0.5 2.4e-17 62.6 0.5 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain COE1_HLH PF16423.5 KFP03779.1 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 Transcription factor COE1 helix-loop-helix domain PMBR PF09373.10 KFP03779.1 - 0.081 13.1 0.1 0.2 11.9 0.0 1.7 2 0 0 2 2 2 0 Pseudomurein-binding repeat RF-1 PF00472.20 KFP03779.1 - 0.15 12.0 0.2 0.22 11.5 0.2 1.2 1 0 0 1 1 1 0 RF-1 domain LicD PF04991.13 KFP03780.1 - 8.8e-07 29.3 0.6 5.9e-06 26.6 0.1 2.5 2 1 1 3 3 3 1 LicD family SPRY PF00622.28 KFP03781.1 - 1.8e-13 50.7 0.1 4.1e-13 49.5 0.1 1.6 1 0 0 1 1 1 1 SPRY domain fn3 PF00041.21 KFP03781.1 - 1.8e-06 28.2 0.0 5.5e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain Helo_like_N PF17111.5 KFP03781.1 - 0.014 14.8 0.5 0.031 13.6 0.5 1.5 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Fib_alpha PF08702.10 KFP03781.1 - 0.021 15.0 2.8 0.04 14.1 2.8 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Ntox28 PF15605.6 KFP03781.1 - 0.026 14.8 0.5 0.11 12.7 0.2 2.1 2 0 0 2 2 2 0 Bacterial toxin 28 COS PF18568.1 KFP03781.1 - 0.13 12.2 0.1 0.28 11.2 0.1 1.6 1 0 0 1 1 1 0 TRIM C-terminal subgroup One Signature domain Hrs_helical PF12210.8 KFP03781.1 - 0.18 12.4 1.1 0.38 11.3 1.1 1.5 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Sec20 PF03908.13 KFP03781.1 - 0.24 11.3 2.2 1.7 8.6 0.6 2.6 1 1 1 2 2 2 0 Sec20 Choline_transpo PF04515.12 KFP03782.1 - 2.4e-102 342.5 37.4 2.4e-102 342.5 37.4 2.1 1 1 1 2 2 2 1 Plasma-membrane choline transporter PBP_N PF17093.5 KFP03782.1 - 2.1 8.6 4.3 21 5.4 0.4 2.6 2 1 0 2 2 2 0 Penicillin-binding protein N-terminus AF-4 PF05110.13 KFP03783.1 - 4.5e-98 329.9 25.3 1.3e-66 225.6 16.6 2.0 1 1 1 2 2 2 2 AF-4 proto-oncoprotein DUF4551 PF15087.6 KFP03783.1 - 6.8 5.4 11.2 8.9 5.0 11.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ins145_P3_rec PF08709.11 KFP03784.1 - 4.5e-15 55.4 0.2 4.8e-15 55.3 0.2 1.0 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor 7tm_4 PF13853.6 KFP03785.1 - 2.7e-22 79.8 2.1 3.2e-22 79.6 2.1 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP03785.1 - 2.5e-17 63.1 3.7 3.3e-17 62.7 3.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP03785.1 - 4.6e-05 22.9 1.5 5.8e-05 22.6 1.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Ribosomal_L27A PF00828.19 KFP03786.1 - 2.2e-28 99.5 0.0 3.1e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Abhydrolase_2 PF02230.16 KFP03787.1 - 1e-74 251.0 0.0 1.2e-74 250.8 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KFP03787.1 - 2.6e-06 26.9 0.0 0.0013 18.1 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KFP03787.1 - 3.9e-06 26.9 0.0 4.4e-05 23.4 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Cutinase PF01083.22 KFP03787.1 - 0.00096 19.2 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.20 KFP03787.1 - 0.0013 18.5 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.8 KFP03787.1 - 0.0043 16.6 0.0 0.0062 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.21 KFP03787.1 - 0.0085 15.6 0.0 2.1 7.8 0.0 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 KFP03787.1 - 0.018 14.6 0.0 0.024 14.2 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KFP03787.1 - 0.023 15.3 0.0 0.023 15.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2920 PF11144.8 KFP03787.1 - 0.063 12.4 0.0 0.19 10.8 0.0 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2920) FSH1 PF03959.13 KFP03787.1 - 0.064 12.9 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Esterase PF00756.20 KFP03787.1 - 0.066 12.9 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 KFP03787.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.12 KFP03787.1 - 0.18 10.4 0.0 0.27 9.9 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) TFIIS_M PF07500.14 KFP03788.1 - 2.1e-37 128.1 2.1 2.1e-37 128.1 2.1 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KFP03788.1 - 2.7e-19 68.7 8.0 6e-19 67.6 8.0 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KFP03788.1 - 3.9e-10 39.6 1.1 1.4e-09 37.9 1.1 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DBD_Tnp_Mut PF03108.15 KFP03788.1 - 0.0017 18.3 0.2 0.0041 17.1 0.2 1.6 1 0 0 1 1 1 1 MuDR family transposase tRNA_synt_1c_R2 PF04557.15 KFP03788.1 - 1.5 9.8 9.1 0.41 11.6 1.4 2.9 2 1 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Ku_C PF03730.14 KFP03788.1 - 5.4 7.8 10.3 0.32 11.7 3.4 2.4 2 1 0 2 2 2 0 Ku70/Ku80 C-terminal arm RGS PF00615.19 KFP03789.1 - 7.4e-35 119.8 1.6 9.8e-35 119.4 1.6 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain V-ATPase_H_N PF03224.14 KFP03790.1 - 2.3e-106 355.7 6.1 2.3e-106 355.7 6.1 1.4 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KFP03790.1 - 4.3e-29 101.0 2.9 8.8e-29 100.0 0.0 2.8 3 0 0 3 3 3 1 V-ATPase subunit H Arm PF00514.23 KFP03790.1 - 1.9e-07 30.9 0.1 0.00039 20.4 0.0 4.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat DRIM PF07539.12 KFP03790.1 - 5e-05 21.8 1.8 0.00082 17.8 0.8 2.1 2 0 0 2 2 2 1 Down-regulated in metastasis DUF2326 PF10088.9 KFP03790.1 - 0.0078 16.0 0.2 0.0078 16.0 0.2 1.9 2 0 0 2 2 2 1 Uncharacterised protein conserved in bacteria (DUF2326) YlbD_coat PF14071.6 KFP03790.1 - 0.013 15.7 2.1 0.013 15.7 2.1 2.0 2 0 0 2 2 2 0 Putative coat protein DUF3829 PF12889.7 KFP03790.1 - 0.049 13.1 0.3 0.049 13.1 0.3 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3829) Muted PF14942.6 KFP03790.1 - 0.063 13.6 6.1 0.14 12.5 0.4 2.4 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein SPOB_ab PF14682.6 KFP03790.1 - 0.1 12.7 1.9 0.2 11.7 0.3 2.4 2 0 0 2 2 2 0 Sporulation initiation phospho-transferase B, C-terminal 7tm_1 PF00001.21 KFP03791.1 - 1.3e-59 201.7 22.2 1.6e-59 201.4 22.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFP03791.1 - 7.5e-09 35.3 16.1 9.9e-09 35.0 16.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.9 KFP03791.1 - 4e-07 29.7 21.8 4.8e-07 29.4 21.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP03791.1 - 0.014 15.1 23.0 0.015 14.9 21.4 1.9 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Saf_2TM PF18303.1 KFP03791.1 - 0.3 10.7 4.4 0.095 12.3 0.8 2.0 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain ATG11 PF10377.9 KFP03792.1 - 1.6e-20 73.4 0.0 1.6e-20 73.4 0.0 5.5 5 1 1 6 6 6 1 Autophagy-related protein 11 TBK1_ULD PF18396.1 KFP03792.1 - 0.0019 18.1 0.1 0.015 15.2 0.0 2.5 2 0 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain Ribosomal_L13 PF00572.18 KFP03792.1 - 0.16 12.2 2.2 6.2 7.1 0.0 3.3 2 1 1 3 3 3 0 Ribosomal protein L13 MYT1 PF08474.11 KFP03793.1 - 9.1e-86 287.7 6.2 9.1e-86 287.7 6.2 2.2 2 0 0 2 2 1 1 Myelin transcription factor 1 zf-C2HC PF01530.18 KFP03793.1 - 1.5e-82 271.4 80.1 1.1e-15 57.5 7.4 6.5 6 0 0 6 6 6 6 Zinc finger, C2HC type DUF1664 PF07889.12 KFP03793.1 - 0.037 14.0 0.9 0.13 12.3 0.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) YabA PF06156.13 KFP03793.1 - 0.12 13.0 7.5 0.06 14.0 3.5 2.7 2 0 0 2 2 2 0 Initiation control protein YabA DUF2408 PF10303.9 KFP03793.1 - 0.15 12.7 3.0 0.42 11.2 1.8 2.5 2 0 0 2 2 1 0 Protein of unknown function (DUF2408) CENP-H PF05837.12 KFP03793.1 - 0.19 12.2 7.8 0.14 12.5 4.1 2.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) ADIP PF11559.8 KFP03793.1 - 0.23 11.5 9.0 0.046 13.8 4.1 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding zf-RAG1 PF10426.9 KFP03793.1 - 0.38 10.9 8.2 9.6 6.4 0.0 5.5 5 0 0 5 5 5 0 Recombination-activating protein 1 zinc-finger domain Prefoldin PF02996.17 KFP03793.1 - 0.38 10.7 6.3 0.17 11.8 2.0 2.5 2 0 0 2 2 2 0 Prefoldin subunit HAUS-augmin3 PF14932.6 KFP03793.1 - 0.68 9.5 11.5 0.075 12.6 6.0 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 FapA PF03961.13 KFP03793.1 - 1.1 7.8 8.5 0.24 10.0 4.5 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF16 PF01519.16 KFP03793.1 - 1.7 9.2 5.8 0.87 10.1 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.12 KFP03793.1 - 2 9.1 11.6 0.3 11.7 3.9 2.9 2 0 0 2 2 2 0 SlyX IBR PF01485.21 KFP03793.1 - 2.5 8.4 21.7 19 5.5 0.2 6.5 3 2 3 6 6 6 0 IBR domain, a half RING-finger domain PCMT PF01135.19 KFP03794.1 - 1.4e-28 100.1 0.0 2e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SOCS_box PF07525.16 KFP03794.1 - 1e-06 29.0 1.2 0.011 16.1 0.8 2.6 2 0 0 2 2 2 2 SOCS box DOT1 PF08123.13 KFP03794.1 - 0.00013 21.6 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 KFP03794.1 - 0.0025 17.6 0.0 0.0041 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 KFP03794.1 - 0.0064 16.2 0.0 0.018 14.8 0.0 1.6 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_25 PF13649.6 KFP03794.1 - 0.014 16.1 0.0 0.033 14.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PDZ PF00595.24 KFP03796.1 - 4e-17 62.3 0.7 6.9e-17 61.6 0.7 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP03796.1 - 1.2e-07 31.4 0.4 2.9e-07 30.2 0.1 1.8 2 0 0 2 2 2 1 PDZ domain PH PF00169.29 KFP03796.1 - 0.00032 21.2 4.6 0.23 12.0 0.3 3.2 2 1 1 3 3 3 2 PH domain Tricorn_PDZ PF14685.6 KFP03796.1 - 0.16 11.9 0.1 0.83 9.7 0.0 2.1 2 0 0 2 2 2 0 Tricorn protease PDZ domain PDZ_2 PF13180.6 KFP03796.1 - 0.2 12.0 0.0 0.4 11.1 0.0 1.4 1 0 0 1 1 1 0 PDZ domain PPDFL PF15060.6 KFP03797.1 - 1.7e-06 28.5 1.2 0.00025 21.5 0.0 2.2 2 0 0 2 2 2 2 Differentiation and proliferation regulator zf-C2H2 PF00096.26 KFP03798.1 - 8.5e-28 95.2 32.3 2.8e-06 27.5 1.3 5.5 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP03798.1 - 3.8e-21 73.9 32.1 6e-05 23.5 1.1 5.7 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP03798.1 - 2.8e-19 68.6 33.4 4.7e-08 33.1 0.5 5.9 5 1 0 5 5 5 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFP03798.1 - 1.5e-14 53.8 26.4 0.00052 20.2 0.1 6.4 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP03798.1 - 1.5e-10 40.8 29.4 0.0011 18.8 0.7 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger zf-met PF12874.7 KFP03798.1 - 1.6e-08 34.6 26.2 0.0033 17.8 0.3 5.9 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFP03798.1 - 6.3e-08 32.8 17.1 0.0042 17.4 2.9 3.5 3 0 0 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 KFP03798.1 - 5e-05 23.1 16.0 1.1 9.2 1.1 5.5 5 0 0 5 5 5 2 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 KFP03798.1 - 0.0047 17.2 22.1 2.1 8.7 0.3 5.1 1 1 4 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 KFP03798.1 - 0.0048 16.9 29.9 0.31 11.1 0.2 5.6 3 1 2 6 6 5 2 BED zinc finger Elf1 PF05129.13 KFP03798.1 - 0.0065 16.5 18.3 0.019 15.0 0.8 3.2 2 1 1 3 3 3 1 Transcription elongation factor Elf1 like zinc_ribbon_15 PF17032.5 KFP03798.1 - 0.0067 17.2 1.0 0.0067 17.2 1.0 2.9 2 1 0 2 2 1 1 zinc-ribbon family DUF4764 PF15961.5 KFP03798.1 - 0.013 14.2 7.9 0.025 13.3 2.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4764) zf-H2C2_5 PF13909.6 KFP03798.1 - 0.039 13.7 0.6 0.039 13.7 0.6 5.6 5 1 0 5 5 4 0 C2H2-type zinc-finger domain PyrI_C PF02748.15 KFP03798.1 - 0.049 13.6 17.5 2.8 7.9 1.6 4.9 5 0 0 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn-ribbon_8 PF09723.10 KFP03798.1 - 0.061 13.4 22.4 0.54 10.4 2.1 4.3 3 1 0 3 3 3 0 Zinc ribbon domain Trm112p PF03966.16 KFP03798.1 - 0.27 11.8 2.2 12 6.5 0.5 3.6 3 1 0 3 3 3 0 Trm112p-like protein zf_UBZ PF18439.1 KFP03798.1 - 0.47 10.1 16.1 17 5.1 0.1 5.4 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-AN1 PF01428.16 KFP03798.1 - 0.73 10.1 26.1 8.4 6.7 1.9 5.3 5 0 0 5 5 5 0 AN1-like Zinc finger zf_ZIC PF18366.1 KFP03798.1 - 0.89 9.7 14.2 12 6.1 1.3 4.9 2 2 3 5 5 5 0 Zic proteins zinc finger domain zinc_ribbon_9 PF14369.6 KFP03798.1 - 1.1 9.6 9.3 0.71 10.2 0.3 4.0 4 0 0 4 4 4 0 zinc-ribbon zf-LYAR PF08790.11 KFP03798.1 - 1.8 8.5 12.9 6 6.9 0.2 4.8 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger Ogr_Delta PF04606.12 KFP03798.1 - 3.2 7.8 12.5 0.058 13.4 3.7 2.6 3 1 0 3 3 3 0 Ogr/Delta-like zinc finger Zn_Tnp_IS1595 PF12760.7 KFP03798.1 - 4 7.5 26.7 0.078 13.0 5.8 4.0 2 2 2 4 4 4 0 Transposase zinc-ribbon domain zf-CHY PF05495.12 KFP03798.1 - 4.9 7.7 26.1 0.97 10.0 6.3 2.6 1 1 0 2 2 2 0 CHY zinc finger Voltage_CLC PF00654.20 KFP03799.1 - 8e-22 78.0 8.6 8.9e-22 77.8 8.6 1.0 1 0 0 1 1 1 1 Voltage gated chloride channel UQ_con PF00179.26 KFP03800.1 - 2e-18 66.4 0.0 2.3e-18 66.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFP03800.1 - 0.0098 16.2 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 1 RWD domain MCM PF00493.23 KFP03801.1 - 1.4e-99 331.7 0.0 2.1e-99 331.2 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFP03801.1 - 2.5e-39 134.0 0.3 4.4e-39 133.2 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFP03801.1 - 6.5e-26 90.6 1.0 2.2e-25 88.9 1.0 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFP03801.1 - 4.7e-19 68.9 3.1 1.3e-18 67.4 1.0 2.5 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFP03801.1 - 5.7e-08 32.4 0.0 1.4e-05 24.6 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFP03801.1 - 8.7e-08 32.3 0.1 6.4e-07 29.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFP03801.1 - 2.9e-05 23.9 0.0 5.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CDT1_C PF16679.5 KFP03801.1 - 0.006 17.0 0.6 0.024 15.0 0.1 2.2 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain Sigma54_activat PF00158.26 KFP03801.1 - 0.014 15.1 0.0 3 7.5 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 KFP03801.1 - 0.032 14.7 0.0 0.098 13.1 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HypA PF01155.19 KFP03801.1 - 0.073 13.1 0.8 0.17 11.9 0.1 2.0 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NTPase_1 PF03266.15 KFP03801.1 - 0.14 12.0 0.4 6.9 6.5 0.0 2.7 2 1 1 3 3 3 0 NTPase FANC_SAP PF18081.1 KFP03801.1 - 0.18 12.0 1.1 1 9.6 1.1 2.4 1 0 0 1 1 1 0 Fanconi anemia-associated nuclease SAP domain CRISPR_Cse2 PF09485.10 KFP03801.1 - 1.2 9.7 3.6 0.79 10.3 0.1 2.5 3 1 0 3 3 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) NUC194 PF08163.12 KFP03802.1 - 7.1e-162 538.7 0.7 1.3e-161 537.9 0.7 1.5 1 0 0 1 1 1 1 NUC194 domain FAT PF02259.23 KFP03802.1 - 1.4e-68 231.7 9.8 1.4e-68 231.7 9.8 2.5 3 0 0 3 3 3 1 FAT domain PI3_PI4_kinase PF00454.27 KFP03802.1 - 3e-63 214.0 1.6 1.3e-62 211.8 0.0 2.6 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KFP03802.1 - 5.6e-12 45.3 0.2 1.3e-11 44.1 0.2 1.7 1 0 0 1 1 1 1 FATC domain TPR_2 PF07719.17 KFP03802.1 - 0.11 12.6 6.2 3.5 8.0 2.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFP03802.1 - 0.17 11.8 3.7 4.7 7.2 1.7 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP03802.1 - 0.17 12.0 1.6 18 5.6 0.5 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFP03802.1 - 9.3 6.8 7.7 1.1e+02 3.4 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4503 PF14951.6 KFP03803.1 - 8.6e-169 561.1 8.5 8.6e-169 561.1 8.5 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4503) DUF4502 PF14950.6 KFP03803.1 - 5.2e-52 177.5 0.5 7.6e-52 177.0 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4502) DUF4502 PF14950.6 KFP03804.1 - 2e-42 146.0 20.3 2.3e-42 145.8 20.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4502) CDP-OH_P_transf PF01066.21 KFP03805.1 - 6.8e-16 58.8 0.4 6.8e-16 58.8 0.4 3.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase EB1 PF03271.17 KFP03806.1 - 2.4e-16 59.7 0.2 9.4e-16 57.8 0.2 2.1 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 KFP03806.1 - 4.3e-13 49.4 0.3 7e-13 48.7 0.3 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFP03806.1 - 0.0018 18.1 0.1 0.0041 16.9 0.1 1.6 1 0 0 1 1 1 1 CAMSAP CH domain ING PF12998.7 KFP03806.1 - 0.063 13.9 1.0 0.15 12.7 1.0 1.8 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding EF-hand_2 PF09068.11 KFP03807.1 - 1.1e-34 119.2 1.5 3e-34 117.8 0.7 2.1 2 0 0 2 2 2 1 EF hand EF-hand_3 PF09069.11 KFP03807.1 - 3.2e-30 104.4 0.1 1.6e-29 102.1 0.0 2.3 2 0 0 2 2 2 1 EF-hand ZZ PF00569.17 KFP03807.1 - 2.9e-09 36.6 9.7 2.9e-09 36.6 9.7 1.6 2 0 0 2 2 2 1 Zinc finger, ZZ type C1_2 PF03107.16 KFP03807.1 - 0.0017 18.6 7.4 0.0036 17.6 7.4 1.5 1 0 0 1 1 1 1 C1 domain Seryl_tRNA_N PF02403.22 KFP03807.1 - 0.019 15.2 7.1 0.08 13.2 7.1 2.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain SOGA PF11365.8 KFP03807.1 - 0.37 12.0 11.4 0.17 13.0 7.7 2.5 2 1 0 2 2 2 0 Protein SOGA FapA PF03961.13 KFP03807.1 - 0.64 8.5 5.0 1.2 7.7 5.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A CRISPR_Cse2 PF09485.10 KFP03807.1 - 0.71 10.4 9.4 1.8 9.1 9.3 1.7 1 1 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) MerR-DNA-bind PF09278.11 KFP03807.1 - 2.3 8.8 11.9 3 8.5 10.1 2.2 1 1 1 2 2 2 0 MerR, DNA binding CEBP_ZZ PF16366.5 KFP03807.1 - 3.7 7.9 12.2 7.9 6.8 12.2 1.5 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Integrase_H2C2 PF17921.1 KFP03808.1 - 0.00019 21.5 3.5 0.0011 19.0 0.2 2.5 2 1 0 2 2 2 1 Integrase zinc binding domain BEN PF10523.9 KFP03808.1 - 0.0081 16.4 0.3 0.29 11.4 0.0 2.8 2 0 0 2 2 2 1 BEN domain DUF3432 PF11914.8 KFP03809.1 - 1.4e-05 25.2 70.3 1.1 9.6 7.7 7.8 1 1 6 7 7 7 7 Domain of unknown function (DUF3432) ASXH PF13919.6 KFP03810.1 - 1.6e-34 118.9 0.2 1.6e-34 118.9 0.2 2.9 3 0 0 3 3 3 1 Asx homology domain PHD_3 PF13922.6 KFP03810.1 - 7.6e-18 64.7 22.2 2.2e-16 60.0 22.2 3.4 1 1 0 1 1 1 1 PHD domain of transcriptional enhancer, Asx HARE-HTH PF05066.13 KFP03810.1 - 2.8e-14 53.3 0.0 6.5e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain PRIMA1 PF16101.5 KFP03810.1 - 0.28 11.2 6.8 1.5 8.9 6.8 2.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Radial_spoke_3 PF06098.11 KFP03811.1 - 0.13 11.6 3.5 0.16 11.2 3.0 1.5 1 1 1 2 2 2 0 Radial spoke protein 3 LRS4 PF10422.9 KFP03812.1 - 0.75 9.3 5.7 1.1 8.7 5.7 1.3 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 DUF4140 PF13600.6 KFP03812.1 - 2.3 8.7 5.5 5.3 7.5 0.9 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TSNAXIP1_N PF15739.5 KFP03812.1 - 8.8 6.8 16.7 0.059 13.7 2.9 2.6 2 1 1 3 3 3 0 Translin-associated factor X-interacting N-terminus RVT_1 PF00078.27 KFP03813.1 - 0.082 12.4 0.0 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFP03814.1 - 0.00025 20.6 0.0 0.00038 20.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ras PF00071.22 KFP03816.1 - 4.7e-45 153.1 0.1 5.9e-45 152.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP03816.1 - 1.6e-20 73.5 0.2 2.4e-20 73.0 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP03816.1 - 1.8e-08 34.1 0.2 2e-08 33.9 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP03816.1 - 0.00034 20.2 0.0 0.00056 19.5 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFP03816.1 - 0.012 14.9 0.2 0.018 14.4 0.1 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region CABIT PF12736.7 KFP03817.1 - 2e-54 184.8 0.4 3.3e-54 184.1 0.4 1.3 1 0 0 1 1 1 1 Cell-cycle sustaining, positive selection, SAM_1 PF00536.30 KFP03817.1 - 0.0027 18.1 0.1 0.0049 17.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PKD PF00801.20 KFP03817.1 - 0.12 12.2 0.1 5.3 7.0 0.2 2.9 3 0 0 3 3 3 0 PKD domain Astacin PF01400.24 KFP03818.1 - 6.7e-71 237.9 0.3 1.4e-70 236.9 0.1 1.6 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) MAM PF00629.23 KFP03818.1 - 2.7e-39 134.7 0.1 6.5e-39 133.4 0.1 1.6 2 0 0 2 2 2 1 MAM domain, meprin/A5/mu EGF PF00008.27 KFP03818.1 - 0.00027 21.1 2.6 0.00076 19.7 2.6 1.8 1 0 0 1 1 1 1 EGF-like domain DAG1 PF05454.11 KFP03818.1 - 0.03 13.7 0.2 0.043 13.2 0.2 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) hEGF PF12661.7 KFP03818.1 - 0.1 13.3 2.7 0.35 11.6 2.7 2.0 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_2 PF07974.13 KFP03818.1 - 1.9 8.9 5.1 6.4 7.2 5.1 1.9 1 0 0 1 1 1 0 EGF-like domain zf_C2HC_14 PF18574.1 KFP03819.1 - 1.7e-16 59.7 7.7 4.8e-16 58.2 7.7 1.8 1 0 0 1 1 1 1 C2HC Zing finger domain zf-Di19 PF05605.12 KFP03819.1 - 8e-16 58.1 1.9 8e-16 58.1 1.9 2.9 2 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_2 PF13923.6 KFP03819.1 - 0.0022 17.8 3.3 0.0022 17.8 3.3 3.6 2 1 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP03819.1 - 0.032 14.6 3.8 0.032 14.6 3.8 4.2 4 1 2 6 6 6 0 Ring finger domain zf-RING_4 PF14570.6 KFP03819.1 - 0.044 13.6 1.3 0.044 13.6 1.3 3.5 4 1 0 4 4 4 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KFP03819.1 - 0.048 13.5 1.2 0.048 13.5 1.2 4.2 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP03819.1 - 0.049 13.5 1.0 0.049 13.5 1.0 4.0 4 0 0 4 4 4 0 Prokaryotic RING finger family 4 zf-C2H2_4 PF13894.6 KFP03819.1 - 0.12 13.3 1.9 0.12 13.3 1.9 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger GAGA PF09237.11 KFP03819.1 - 0.67 9.8 13.5 0.14 11.9 2.6 3.5 2 1 1 3 3 3 0 GAGA factor zf_C2HC_14 PF18574.1 KFP03820.1 - 5.4e-16 58.1 6.5 5.4e-16 58.1 6.5 2.0 2 0 0 2 2 2 1 C2HC Zing finger domain zf-Di19 PF05605.12 KFP03820.1 - 0.004 17.4 1.2 0.004 17.4 1.2 3.8 3 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding CDC24_OB3 PF17244.2 KFP03820.1 - 0.17 11.5 3.8 0.1 12.3 2.4 1.3 1 1 0 1 1 1 0 Cell division control protein 24, OB domain 3 TRAPPC-Trs85 PF12739.7 KFP03821.1 - 5.3e-88 295.7 6.6 1e-87 294.8 6.6 1.5 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit SNAP PF14938.6 KFP03821.1 - 0.03 13.7 3.9 0.064 12.7 0.2 2.5 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP Glyco_transf_7N PF13733.6 KFP03822.1 - 1.4e-54 183.4 0.0 2.1e-54 182.8 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 KFP03822.1 - 3.9e-28 96.9 0.7 6.8e-28 96.1 0.7 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Transthyretin PF00576.21 KFP03823.1 - 1.2e-13 51.7 0.1 1.5e-13 51.3 0.1 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family Transthyretin PF00576.21 KFP03824.1 - 7.9e-21 74.8 0.1 1e-20 74.5 0.1 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family Lipase_C PF18067.1 KFP03824.1 - 0.016 15.8 0.0 0.023 15.2 0.0 1.3 1 0 0 1 1 1 0 Lipase C-terminal domain Cadherin PF00028.17 KFP03825.1 - 1.6e-58 195.2 4.1 3.3e-18 65.9 0.0 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_2 PF08266.12 KFP03825.1 - 6.5e-07 29.1 0.0 0.21 11.5 0.0 4.3 4 1 0 4 4 4 2 Cadherin-like Cadherin_C PF01049.17 KFP03825.1 - 0.00038 20.8 0.0 0.00068 20.0 0.0 1.4 1 0 0 1 1 1 1 Cadherin cytoplasmic region RET_CLD1 PF17756.1 KFP03825.1 - 0.09 13.1 0.0 0.6 10.4 0.0 2.3 2 0 0 2 2 2 0 RET Cadherin like domain 1 DUF4690 PF15756.5 KFP03825.1 - 0.12 13.0 3.2 0.67 10.6 0.0 3.3 3 0 0 3 3 3 0 Small Novel Rich in Cartilage SEC-C PF02810.15 KFP03825.1 - 0.51 10.3 2.0 1.4 8.9 2.0 1.7 1 0 0 1 1 1 0 SEC-C motif Cadherin PF00028.17 KFP03826.1 - 3.6e-52 174.8 0.1 4.7e-16 59.0 0.0 4.4 4 0 0 4 4 4 4 Cadherin domain Cadherin_C PF01049.17 KFP03826.1 - 1e-06 29.1 0.0 2.1e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.12 KFP03826.1 - 0.0045 16.8 0.0 2.9 7.8 0.0 3.2 3 0 0 3 3 3 2 Cadherin-like Cadherin PF00028.17 KFP03827.1 - 2.1e-64 214.0 2.3 1.1e-14 54.6 0.0 6.2 7 0 0 7 7 7 5 Cadherin domain Cadherin_pro PF08758.11 KFP03827.1 - 3.4e-18 65.6 0.4 8.7e-17 61.1 0.3 3.0 3 0 0 3 3 3 1 Cadherin prodomain like Cadherin_C PF01049.17 KFP03827.1 - 2.3e-07 31.3 0.1 5e-07 30.1 0.1 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_3 PF16184.5 KFP03827.1 - 0.00038 20.4 2.8 8 6.5 0.0 4.3 4 0 0 4 4 4 2 Cadherin-like Cadherin_2 PF08266.12 KFP03827.1 - 0.0029 17.4 0.0 8.5 6.3 0.0 3.5 4 0 0 4 4 4 2 Cadherin-like Cadherin PF00028.17 KFP03828.1 - 9e-91 298.5 2.0 8.7e-23 80.6 0.1 5.8 6 0 0 6 6 6 5 Cadherin domain Cadherin_C PF01049.17 KFP03828.1 - 1.5e-53 181.0 0.4 2.9e-53 180.1 0.4 1.4 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_pro PF08758.11 KFP03828.1 - 2.9e-29 101.1 0.2 2.9e-28 97.8 0.1 2.4 2 0 0 2 2 2 1 Cadherin prodomain like Cadherin_3 PF16184.5 KFP03828.1 - 4.5e-07 29.8 6.4 0.079 13.0 0.1 4.7 4 0 0 4 4 4 3 Cadherin-like He_PIG PF05345.12 KFP03828.1 - 3.7e-06 27.0 2.9 0.89 9.8 0.4 5.7 5 0 0 5 5 5 2 Putative Ig domain Cadherin_2 PF08266.12 KFP03828.1 - 6.7e-05 22.7 0.0 3.8 7.4 0.0 3.4 3 0 0 3 3 3 2 Cadherin-like EphA2_TM PF14575.6 KFP03828.1 - 0.015 16.1 0.0 0.035 15.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Cadherin_4 PF17803.1 KFP03828.1 - 0.089 13.4 21.3 0.33 11.6 0.1 5.0 5 1 0 5 5 4 0 Bacterial cadherin-like domain Prok-E2_A PF14457.6 KFP03828.1 - 0.1 12.2 0.3 6.7 6.3 0.2 2.3 2 0 0 2 2 2 0 Prokaryotic E2 family A Stevor PF17410.2 KFP03828.1 - 0.13 11.8 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4381 PF14316.6 KFP03828.1 - 0.19 12.0 0.1 0.34 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF5385 PF17359.2 KFP03828.1 - 1.6 8.3 4.4 0.22 11.1 0.2 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5385) Sulfotransfer_2 PF03567.14 KFP03829.1 - 2.3e-61 207.9 1.6 2.9e-61 207.6 1.6 1.1 1 0 0 1 1 1 1 Sulfotransferase family MIP PF00230.20 KFP03830.1 - 3.3e-73 246.2 13.9 4.1e-73 245.8 13.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein BTB_2 PF02214.22 KFP03831.1 - 2.5e-17 63.0 0.0 4e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain TAF4 PF05236.14 KFP03832.1 - 4.5e-51 174.2 8.6 7.4e-51 173.5 8.6 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TAFH PF07531.14 KFP03832.1 - 1.9e-38 130.5 4.2 1.9e-38 130.5 4.2 2.3 2 0 0 2 2 2 1 NHR1 homology to TAF SSXT PF05030.12 KFP03833.1 - 8e-27 92.7 4.2 1.5e-26 91.8 4.2 1.4 1 0 0 1 1 1 1 SSXT protein (N-terminal region) zf-C2H2_4 PF13894.6 KFP03834.1 - 5.8e-68 219.6 213.6 0.00037 21.1 0.8 31.2 31 0 0 31 31 31 26 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP03834.1 - 1.6e-49 163.7 219.0 0.0012 19.2 3.0 30.7 31 0 0 31 31 31 24 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFP03834.1 - 4.9e-33 112.5 181.0 9e-08 31.9 0.1 26.5 26 1 1 27 27 26 14 C2H2-type zinc finger zf-Di19 PF05605.12 KFP03834.1 - 1.2e-21 76.8 168.6 6.5e-05 23.1 3.4 19.3 15 3 4 20 20 20 12 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KFP03834.1 - 1.3e-19 69.6 187.4 6.7e-06 26.3 1.0 28.3 32 1 0 32 32 31 13 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFP03834.1 - 4.8e-09 36.3 181.6 0.013 15.7 0.6 25.8 29 0 0 29 29 28 11 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFP03834.1 - 2.8e-05 24.4 167.5 0.11 12.9 0.9 24.5 8 6 13 22 22 22 9 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFP03834.1 - 0.00014 22.1 14.1 0.0079 16.6 1.2 21.6 25 0 0 25 25 25 8 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFP03834.1 - 0.01 16.1 1.6 0.01 16.1 1.6 13.8 9 4 5 14 14 14 0 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 KFP03834.1 - 0.063 13.2 0.1 0.063 13.2 0.1 16.5 17 1 1 18 18 17 0 zinc-finger of a C2HC-type Zn-C2H2_12 PF18112.1 KFP03834.1 - 0.11 13.0 0.2 0.11 13.0 0.2 10.8 13 0 0 13 13 10 0 Autophagy receptor zinc finger-C2H2 domain 7tm_1 PF00001.21 KFP03835.1 - 2.5e-61 207.3 8.1 2.9e-61 207.1 8.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP03835.1 - 4.8e-07 29.4 10.7 0.00017 21.0 5.3 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP03835.1 - 0.00023 21.0 6.6 0.00043 20.1 6.6 1.5 1 0 0 1 1 1 1 Olfactory receptor UPF0029 PF01205.19 KFP03836.1 - 4.4e-35 120.2 0.0 6.9e-35 119.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KFP03836.1 - 5.5e-17 62.1 1.0 5.5e-17 62.1 1.0 1.7 2 1 0 2 2 2 1 RWD domain Oxysterol_BP PF01237.18 KFP03837.1 - 5.6e-151 502.6 0.8 7.7e-151 502.2 0.8 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein Ank PF00023.30 KFP03837.1 - 2.2e-22 78.4 4.9 5.5e-08 32.9 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KFP03837.1 - 2.2e-22 78.8 2.8 5.2e-09 36.2 0.1 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP03837.1 - 1.4e-21 76.9 1.4 4.4e-13 49.6 0.2 2.9 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP03837.1 - 9.3e-20 70.7 2.7 7.5e-05 23.2 0.0 5.4 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP03837.1 - 1.3e-15 55.9 0.6 5.1e-05 23.4 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat PH PF00169.29 KFP03837.1 - 0.024 15.2 0.5 0.024 15.2 0.5 3.1 3 0 0 3 3 3 0 PH domain PH_11 PF15413.6 KFP03837.1 - 0.042 14.3 0.2 0.042 14.3 0.2 3.6 3 0 0 3 3 3 0 Pleckstrin homology domain DUF3808 PF10300.9 KFP03838.1 - 5.4e-126 421.1 6.7 6.5e-126 420.9 6.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Cohesin_load PF10345.9 KFP03838.1 - 3e-07 29.3 0.8 7.7e-07 27.9 0.8 1.7 1 0 0 1 1 1 1 Cohesin loading factor TPR_2 PF07719.17 KFP03838.1 - 3.1e-06 26.9 1.9 0.095 12.9 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFP03838.1 - 4.5e-05 23.1 1.2 0.076 12.9 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFP03838.1 - 0.00097 19.4 0.5 0.72 10.2 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFP03838.1 - 0.0014 19.1 0.4 12 6.8 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat VEFS-Box PF09733.9 KFP03838.1 - 0.015 15.1 0.2 0.045 13.5 0.0 1.9 2 0 0 2 2 2 0 VEFS-Box of polycomb protein TPR_7 PF13176.6 KFP03838.1 - 0.016 15.2 0.3 0.15 12.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFP03838.1 - 0.063 14.1 0.1 2 9.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFP03838.1 - 0.1 12.8 0.5 2.3 8.6 0.0 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Laminin_EGF PF00053.24 KFP03839.1 - 1.8e-97 319.3 310.8 6.1e-10 39.1 12.2 17.1 15 2 2 17 17 17 15 Laminin EGF domain Laminin_G_2 PF02210.24 KFP03839.1 - 4.7e-77 256.6 0.0 3.9e-23 82.4 0.1 5.7 5 0 0 5 5 5 5 Laminin G domain Laminin_N PF00055.17 KFP03839.1 - 1.4e-68 231.0 0.0 1.4e-68 231.0 0.0 3.1 3 0 0 3 3 3 1 Laminin N-terminal (Domain VI) Laminin_G_1 PF00054.23 KFP03839.1 - 8.4e-63 210.4 0.6 5.4e-21 75.2 0.1 6.1 5 1 1 6 6 6 4 Laminin G domain Laminin_I PF06008.14 KFP03839.1 - 7.4e-52 176.6 32.3 7.4e-52 176.6 32.3 3.2 2 1 0 3 3 3 1 Laminin Domain I Laminin_II PF06009.12 KFP03839.1 - 5.3e-35 120.4 0.6 5.3e-35 120.4 0.6 5.5 3 2 2 5 5 5 1 Laminin Domain II Laminin_B PF00052.18 KFP03839.1 - 7.7e-31 106.8 0.0 2e-30 105.4 0.0 1.8 1 0 0 1 1 1 1 Laminin B (Domain IV) Laminin_G_3 PF13385.6 KFP03839.1 - 3.3e-14 53.3 0.0 0.00016 21.9 0.0 4.2 4 0 0 4 4 4 2 Concanavalin A-like lectin/glucanases superfamily Activator-TraM PF11657.8 KFP03839.1 - 0.043 13.6 4.6 0.039 13.8 2.7 1.9 1 1 0 1 1 1 0 Transcriptional activator TraM Polysacc_lyase PF14099.6 KFP03839.1 - 0.083 12.7 0.0 18 5.1 0.0 2.6 2 0 0 2 2 2 0 Polysaccharide lyase Ank_2 PF12796.7 KFP03840.1 - 4.3e-48 161.8 0.8 4.4e-14 52.8 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP03840.1 - 3.2e-41 139.2 6.9 1.5e-08 35.0 0.1 6.3 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 KFP03840.1 - 3.1e-33 112.8 7.0 4.2e-05 23.8 0.0 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 KFP03840.1 - 1.4e-30 104.9 6.1 1e-08 35.2 0.1 7.5 2 1 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP03840.1 - 3.1e-28 94.7 0.7 0.021 15.3 0.0 8.2 8 0 0 8 8 8 6 Ankyrin repeat NIT PF08376.10 KFP03840.1 - 0.031 14.7 1.2 0.19 12.2 1.2 2.2 1 1 0 1 1 1 0 Nitrate and nitrite sensing Patched PF02460.18 KFP03841.1 - 1.4e-82 278.2 22.1 4.5e-82 276.4 21.3 2.2 1 1 1 2 2 2 1 Patched family NPC1_N PF16414.5 KFP03841.1 - 4.5e-79 265.4 4.6 4.5e-79 265.4 4.6 2.1 2 0 0 2 2 2 1 Niemann-Pick C1 N terminus Sterol-sensing PF12349.8 KFP03841.1 - 4.2e-57 192.3 6.4 4.2e-57 192.3 6.4 2.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 KFP03841.1 - 2.5e-05 23.4 4.2 2.5e-05 23.4 4.2 2.3 2 0 0 2 2 2 1 MMPL family ACR_tran PF00873.19 KFP03841.1 - 0.0002 19.2 7.1 0.0002 19.2 7.1 2.2 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family Mic1 PF07035.12 KFP03842.1 - 2.3e-70 235.4 2.4 2.9e-70 235.0 1.1 1.8 2 0 0 2 2 2 1 Colon cancer-associated protein Mic1-like RIO1 PF01163.22 KFP03843.1 - 4e-75 251.5 0.3 9.5e-75 250.3 0.3 1.7 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 KFP03843.1 - 0.00042 19.8 0.3 0.001 18.5 0.3 1.6 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KFP03843.1 - 0.0029 17.0 0.2 0.012 15.0 0.2 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFP03843.1 - 0.026 14.1 0.1 0.064 12.8 0.1 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 KFP03843.1 - 0.042 13.8 0.2 0.79 9.6 0.2 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family TPT PF03151.16 KFP03844.1 - 4.8e-06 26.1 1.0 6.3e-06 25.7 1.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family TssN PF17555.2 KFP03844.1 - 0.03 13.7 2.1 0.05 13.0 2.1 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssN EamA PF00892.20 KFP03844.1 - 0.17 12.0 15.9 0.6 10.3 6.9 2.2 2 0 0 2 2 2 0 EamA-like transporter family Cyclin_N PF00134.23 KFP03845.1 - 5.8e-08 32.5 0.2 8.7e-08 32.0 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain CtIP_N PF10482.9 KFP03846.1 - 7e-51 171.3 21.0 7e-51 171.3 21.0 2.4 2 0 0 2 2 2 1 Tumour-suppressor protein CtIP N-terminal domain SAE2 PF08573.10 KFP03846.1 - 3.5e-05 24.9 0.3 3.5e-05 24.9 0.3 5.3 4 1 1 5 5 5 2 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF4407 PF14362.6 KFP03846.1 - 8.8 5.6 13.3 0.15 11.4 5.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Ank_2 PF12796.7 KFP03848.1 - 2.5e-48 162.6 10.5 7.3e-15 55.3 0.0 5.0 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP03848.1 - 4.1e-47 157.6 13.3 2.8e-13 49.8 0.0 7.2 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP03848.1 - 7.2e-46 154.0 19.7 3.5e-11 43.4 0.1 7.7 2 1 7 9 9 9 8 Ankyrin repeats (many copies) SH3_15 PF18346.1 KFP03848.1 - 5.6e-44 148.3 6.3 1.5e-21 76.5 0.0 3.6 4 0 0 4 4 4 2 Mind bomb SH3 repeat domain Ank PF00023.30 KFP03848.1 - 8.8e-41 136.6 12.7 3.9e-08 33.4 0.9 9.2 8 1 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.6 KFP03848.1 - 2.2e-29 98.2 16.1 0.00058 20.1 0.3 10.5 12 0 0 12 12 10 6 Ankyrin repeat MIB_HERC2 PF06701.13 KFP03848.1 - 1.4e-28 98.9 4.8 1.4e-28 98.9 4.8 4.0 4 0 0 4 4 4 1 Mib_herc2 zf-C3HC4_3 PF13920.6 KFP03848.1 - 2.8e-27 94.3 59.7 1.8e-10 40.5 7.9 4.7 4 1 0 4 4 4 3 Zinc finger, C3HC4 type (RING finger) ZZ PF00569.17 KFP03848.1 - 2.5e-11 43.2 8.4 2.5e-11 43.2 8.4 3.6 3 0 0 3 3 2 1 Zinc finger, ZZ type zf-C3HC4_2 PF13923.6 KFP03848.1 - 2.7e-08 33.5 9.8 2.7e-08 33.5 9.8 4.7 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP03848.1 - 0.00058 19.7 55.8 0.0095 15.8 8.3 5.1 4 1 1 5 5 4 3 Prokaryotic RING finger family 4 Hydrolase_4 PF12146.8 KFP03849.1 - 3.4e-09 36.3 0.0 4.9e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFP03849.1 - 5.4e-09 36.1 0.0 4.2e-08 33.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFP03849.1 - 1.8e-05 25.5 0.0 2.7e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Acetyltransf_13 PF13880.6 KFP03850.1 - 7.3e-30 102.8 0.0 1.5e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 KFP03850.1 - 3.1e-15 55.7 0.0 6.9e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO GREB1 PF15782.5 KFP03851.1 - 0 3220.1 11.2 0 3219.9 11.2 1.0 1 0 0 1 1 1 1 Gene regulated by oestrogen in breast cancer Rcd1 PF04078.13 KFP03851.1 - 0.0093 15.3 0.2 0.018 14.4 0.2 1.4 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Pkinase PF00069.25 KFP03852.1 - 1.6e-62 211.2 0.0 1.6e-62 211.2 0.0 3.7 4 2 0 4 4 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP03852.1 - 4e-30 105.0 0.0 4e-30 105.0 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase Rho_Binding PF08912.11 KFP03852.1 - 3.4e-22 79.0 12.1 3.4e-22 79.0 12.1 13.4 4 3 8 13 13 10 1 Rho Binding PH PF00169.29 KFP03852.1 - 4.1e-06 27.3 3.7 9.4e-05 22.9 0.1 3.3 3 0 0 3 3 3 1 PH domain C1_1 PF00130.22 KFP03852.1 - 0.0004 20.2 5.9 0.00083 19.2 5.9 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) APH PF01636.23 KFP03852.1 - 0.00098 19.1 0.3 0.029 14.3 0.2 2.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family FPP PF05911.11 KFP03852.1 - 0.0021 16.3 36.4 0.0021 16.3 36.4 5.1 1 1 4 5 5 3 1 Filament-like plant protein, long coiled-coil Cortex-I_coil PF09304.10 KFP03852.1 - 0.0033 17.6 9.5 0.0033 17.6 9.5 8.7 1 1 8 10 10 4 1 Cortexillin I, coiled coil HR1 PF02185.16 KFP03852.1 - 0.0068 16.5 13.5 0.0068 16.5 13.5 10.7 6 3 3 9 9 5 2 Hr1 repeat Pkinase_C PF00433.24 KFP03852.1 - 0.022 15.5 4.1 0.073 13.8 4.1 2.0 1 1 0 1 1 1 0 Protein kinase C terminal domain DUF1192 PF06698.11 KFP03852.1 - 0.026 14.5 0.6 0.026 14.5 0.6 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) UCH PF00443.29 KFP03853.1 - 4.8e-50 170.5 0.6 5.7e-50 170.2 0.6 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP03853.1 - 9.9e-13 48.4 4.5 2.4e-12 47.1 4.5 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KFP03853.1 - 0.00059 19.5 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.6 KFP03853.1 - 0.00074 19.1 1.9 0.019 14.4 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase PFEMP PF03011.15 KFP03853.1 - 1.2 9.7 7.6 1.8 9.2 0.1 2.8 3 0 0 3 3 3 0 PFEMP DBL domain efThoc1 PF11957.8 KFP03854.1 - 1.8e-146 488.7 8.4 2.9e-146 488.0 8.4 1.3 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Death PF00531.22 KFP03854.1 - 5.1e-18 65.0 1.6 2.3e-17 62.9 0.5 2.5 2 0 0 2 2 2 1 Death domain CARD_2 PF16739.5 KFP03854.1 - 0.083 12.9 0.6 0.26 11.3 0.2 2.1 2 0 0 2 2 2 0 Caspase recruitment domain DUF4093 PF13331.6 KFP03854.1 - 0.16 12.5 1.9 12 6.4 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4093) Collagen PF01391.18 KFP03855.1 - 8.2e-24 83.1 103.6 1.3e-09 37.7 34.7 3.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Lectin_C PF00059.21 KFP03855.1 - 8.3e-21 74.8 1.6 8.3e-21 74.8 1.6 2.3 2 0 0 2 2 2 1 Lectin C-type domain Spc7 PF08317.11 KFP03855.1 - 0.00041 19.3 33.0 0.0073 15.2 14.0 2.5 1 1 1 2 2 2 2 Spc7 kinetochore protein Filament PF00038.21 KFP03855.1 - 0.0013 18.4 30.3 0.0013 18.4 30.3 2.1 1 1 1 2 2 2 1 Intermediate filament protein Fib_alpha PF08702.10 KFP03855.1 - 0.0067 16.6 6.8 0.0067 16.6 6.8 4.1 1 1 3 4 4 4 2 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KFP03855.1 - 0.13 12.3 30.3 1.5 8.9 7.5 4.5 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF3584 PF12128.8 KFP03855.1 - 0.66 7.4 35.8 0.15 9.5 6.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) HalX PF08663.10 KFP03855.1 - 1.2 9.5 4.4 14 6.0 0.0 3.4 2 2 1 3 3 3 0 HalX domain GAS PF13851.6 KFP03855.1 - 3.1 7.1 37.3 0.055 12.8 7.4 3.1 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 KFP03855.1 - 4.6 6.2 32.6 0.088 11.9 14.0 2.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4208 PF13907.6 KFP03855.1 - 4.7 7.7 7.7 2.6 8.5 1.7 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4208) DUF948 PF06103.11 KFP03855.1 - 4.8 7.5 28.2 1.2 9.4 1.7 5.1 2 2 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Jnk-SapK_ap_N PF09744.9 KFP03855.1 - 9.8 6.4 27.5 0.85 9.8 6.5 3.5 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Clusterin PF01093.17 KFP03856.1 - 6.4e-167 556.0 11.4 7.3e-167 555.8 11.4 1.0 1 0 0 1 1 1 1 Clusterin Carbpep_Y_N PF05388.11 KFP03856.1 - 0.0074 16.8 4.2 0.91 10.1 4.6 3.1 2 1 1 3 3 3 1 Carboxypeptidase Y pro-peptide Sulfatase_C PF14707.6 KFP03856.1 - 0.011 16.4 11.8 0.26 12.0 0.2 3.5 2 2 1 3 3 3 0 C-terminal region of aryl-sulfatase L27_1 PF09058.10 KFP03856.1 - 0.042 13.8 0.7 0.23 11.5 0.4 2.4 2 0 0 2 2 2 0 L27_1 Fib_alpha PF08702.10 KFP03856.1 - 0.062 13.5 8.7 1.2 9.3 1.3 2.9 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Cbl_N PF02262.16 KFP03856.1 - 0.4 10.7 7.5 18 5.4 0.0 3.6 3 1 0 3 3 3 0 CBL proto-oncogene N-terminal domain 1 DUF745 PF05335.13 KFP03856.1 - 0.84 9.3 5.9 38 3.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) FapA PF03961.13 KFP03856.1 - 0.86 8.1 4.9 5 5.6 4.2 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A ALIX_LYPXL_bnd PF13949.6 KFP03856.1 - 2.1 7.5 15.0 4.8 6.4 6.7 3.5 2 2 2 4 4 4 0 ALIX V-shaped domain binding to HIV Thymidylat_synt PF00303.19 KFP03857.1 - 8.2e-120 398.9 0.0 9.3e-120 398.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Pkinase_Tyr PF07714.17 KFP03858.1 - 7.1e-93 310.6 0.0 9e-93 310.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP03858.1 - 1.5e-45 155.7 0.0 2e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFP03858.1 - 3.2e-28 97.7 0.2 6.2e-28 96.7 0.2 1.5 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFP03858.1 - 7.3e-20 70.3 0.4 3.3e-19 68.2 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFP03858.1 - 6.3e-15 54.8 0.0 1.9e-14 53.2 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP03858.1 - 4.6e-11 42.2 0.1 1.4e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Haspin_kinase PF12330.8 KFP03858.1 - 0.0023 17.0 0.0 0.004 16.1 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain SH3_10 PF17902.1 KFP03858.1 - 0.004 17.2 0.0 0.0086 16.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.11 KFP03858.1 - 0.014 15.6 0.1 0.033 14.5 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain zf-RING_14 PF17978.1 KFP03858.1 - 0.057 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain YdjC PF04794.12 KFP03858.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 YdjC-like protein hSH3 PF14603.6 KFP03858.1 - 0.12 12.8 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Helically-extended SH3 domain MT-A70 PF05063.14 KFP03859.1 - 1.9e-28 99.5 0.5 3.1e-28 98.9 0.5 1.3 1 0 0 1 1 1 1 MT-A70 N6-adenineMlase PF10237.9 KFP03859.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase Ndc80_HEC PF03801.13 KFP03860.1 - 8.5e-50 168.3 0.0 4.7e-49 165.9 0.0 2.3 2 0 0 2 2 2 1 HEC/Ndc80p family DUF5595 PF18077.1 KFP03860.1 - 1.9e-32 111.2 3.6 1.9e-32 111.2 3.6 6.0 5 2 3 8 8 8 1 Domain of unknown function (DUF5595) KASH_CCD PF14662.6 KFP03860.1 - 0.0026 17.6 10.8 0.0026 17.6 10.8 3.7 2 2 1 3 3 3 1 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 KFP03860.1 - 0.0027 17.8 0.8 0.0027 17.8 0.8 5.5 4 2 1 5 5 5 1 bZIP transcription factor DUF4164 PF13747.6 KFP03860.1 - 0.02 15.2 4.4 0.02 15.2 4.4 4.0 2 2 1 3 3 3 0 Domain of unknown function (DUF4164) HrpB7 PF09486.10 KFP03860.1 - 3.1 8.2 31.1 0.082 13.3 7.3 4.0 2 2 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) GABP-alpha PF11620.8 KFP03860.1 - 4.5 7.5 9.2 20 5.5 1.3 3.6 3 1 0 3 3 3 0 GA-binding protein alpha chain DUF1192 PF06698.11 KFP03860.1 - 4.6 7.4 13.6 5.7 7.1 0.3 4.7 3 1 2 5 5 5 0 Protein of unknown function (DUF1192) HATPase_c_3 PF13589.6 KFP03861.1 - 2.1e-14 53.5 0.0 3.8e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KFP03861.1 - 0.00061 20.3 0.0 0.001 19.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Vinculin PF01044.19 KFP03862.1 - 6e-229 762.9 39.8 3.7e-179 598.1 23.5 2.0 1 1 1 2 2 2 2 Vinculin family AAA_32 PF13654.6 KFP03862.1 - 0.04 12.7 17.5 0.19 10.4 0.1 4.0 2 1 1 4 4 4 0 AAA domain DUF5564 PF17719.1 KFP03862.1 - 0.18 12.0 2.0 1.8 8.8 0.2 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5564) EcsC PF12787.7 KFP03862.1 - 1.2 8.8 6.2 6.3 6.4 0.0 3.8 4 1 0 4 4 4 0 EcsC protein family adh_short_C2 PF13561.6 KFP03862.1 - 2.3 7.7 5.5 6.5 6.2 0.1 3.3 4 0 0 4 4 4 0 Enoyl-(Acyl carrier protein) reductase LRR_8 PF13855.6 KFP03863.1 - 2.9e-55 183.9 63.3 2.6e-14 52.7 5.7 5.8 1 1 5 6 6 6 6 Leucine rich repeat LRR_5 PF13306.6 KFP03863.1 - 2.9e-30 104.9 0.2 7.6e-13 48.5 0.2 3.0 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFP03863.1 - 4.8e-19 68.1 39.5 5.7e-05 23.4 3.3 6.5 1 1 7 9 9 9 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP03863.1 - 4.2e-10 39.4 7.5 0.00017 21.1 3.6 3.5 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 KFP03863.1 - 5.9e-07 29.2 38.7 1.2 9.9 0.6 10.6 10 1 0 10 10 10 2 Leucine Rich Repeat LRR_6 PF13516.6 KFP03863.1 - 6.9e-06 25.7 30.7 1.1 9.5 0.2 9.6 10 0 0 10 10 10 2 Leucine Rich repeat LRRNT PF01462.18 KFP03863.1 - 3e-05 23.6 0.6 3e-05 23.6 0.6 2.5 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain EphA2_TM PF14575.6 KFP03863.1 - 0.12 13.3 0.3 0.33 11.8 0.1 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain LRR_2 PF07723.13 KFP03863.1 - 6.2 7.7 12.7 10 7.0 0.2 6.3 7 1 1 8 8 8 0 Leucine Rich Repeat DnaJ PF00226.31 KFP03864.1 - 1.4e-19 70.0 0.1 3.5e-19 68.7 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain SIR2 PF02146.17 KFP03865.1 - 1.6e-63 213.8 0.0 2.7e-63 213.1 0.0 1.4 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KFP03865.1 - 0.0011 18.7 0.0 0.44 10.3 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 KFP03865.1 - 0.006 16.4 0.2 0.01 15.6 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) HECT PF00632.25 KFP03866.1 - 2.6e-90 303.1 0.2 1e-89 301.1 0.1 2.0 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.18 KFP03866.1 - 1.2e-89 294.7 21.2 7.9e-15 55.2 0.1 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFP03866.1 - 5.5e-48 159.9 33.4 8.4e-10 38.2 0.3 7.6 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat HLH PF00010.26 KFP03867.1 - 1.2e-18 66.8 0.1 1.7e-18 66.3 0.1 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DERM PF14704.6 KFP03867.1 - 0.03 14.8 0.9 0.45 11.0 0.2 2.1 1 1 1 2 2 2 0 Dermatopontin DUF1295 PF06966.12 KFP03867.1 - 0.11 12.0 0.1 0.15 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) PhzC-PhzF PF02567.16 KFP03868.1 - 4.5e-61 206.8 0.0 5.1e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein RRM_1 PF00076.22 KFP03869.1 - 1e-21 76.5 0.0 1.1e-10 41.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dna2 PF08696.11 KFP03870.1 - 7.3e-62 208.8 0.1 1.5e-61 207.7 0.1 1.6 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 KFP03870.1 - 2.2e-48 164.5 0.4 3.5e-31 108.4 0.1 2.9 2 1 1 3 3 3 2 AAA domain AAA_11 PF13086.6 KFP03870.1 - 1.5e-32 113.4 0.4 3.5e-16 59.8 0.2 2.6 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 KFP03870.1 - 2e-15 57.0 0.0 6.7e-15 55.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFP03870.1 - 1.9e-12 47.7 0.0 1.2e-10 41.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KFP03870.1 - 3.1e-09 36.9 0.6 0.0026 17.6 0.1 4.2 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PDDEXK_1 PF12705.7 KFP03870.1 - 6.2e-09 36.1 0.0 8.9e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.17 KFP03870.1 - 1.7e-05 25.0 6.1 0.0057 16.8 1.8 3.6 2 1 0 2 2 2 1 Domain of unknown function DUF83 SRP54 PF00448.22 KFP03870.1 - 0.0024 17.5 0.0 0.0062 16.2 0.0 1.7 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain UvrD_C_2 PF13538.6 KFP03870.1 - 0.0025 17.6 0.0 0.005 16.6 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain cobW PF02492.19 KFP03870.1 - 0.0039 16.8 0.0 0.008 15.8 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 KFP03870.1 - 0.0088 15.6 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 KFP03870.1 - 0.0098 15.4 0.3 0.074 12.5 0.0 2.7 3 0 0 3 3 3 1 PhoH-like protein CbiA PF01656.23 KFP03870.1 - 0.0099 15.9 2.4 0.071 13.2 2.3 2.5 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain UvrD-helicase PF00580.21 KFP03870.1 - 0.014 14.9 2.6 0.034 13.7 0.0 2.7 2 1 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_7 PF12775.7 KFP03870.1 - 0.016 14.8 0.2 0.033 13.7 0.2 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF853 PF05872.12 KFP03870.1 - 0.02 13.5 0.1 0.031 12.9 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA PF00004.29 KFP03870.1 - 0.027 14.9 0.1 0.089 13.2 0.1 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFP03870.1 - 0.039 14.3 0.0 0.092 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KFP03870.1 - 0.044 14.3 2.1 0.12 12.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KFP03870.1 - 0.07 12.9 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Helicase_RecD PF05127.14 KFP03870.1 - 0.076 12.9 0.0 0.28 11.0 0.0 2.0 2 1 0 2 2 1 0 Helicase ResIII PF04851.15 KFP03870.1 - 0.083 12.9 0.5 0.53 10.3 0.3 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KFP03870.1 - 0.092 13.0 0.1 0.97 9.7 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KFP03870.1 - 0.095 12.7 0.9 0.42 10.6 0.1 2.6 4 0 0 4 4 1 0 AAA domain (dynein-related subfamily) MobB PF03205.14 KFP03870.1 - 0.14 12.1 0.1 0.36 10.7 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 KFP03870.1 - 0.15 12.6 0.1 0.48 11.0 0.1 1.9 1 0 0 1 1 1 0 AAA domain Mito_carr PF00153.27 KFP03871.1 - 1.1e-67 224.0 6.8 5.5e-23 80.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFP03871.1 - 6.2e-05 22.3 1.1 0.014 14.5 0.2 2.8 2 2 1 3 3 3 2 Gammaproteobacterial serine protease Tet_JBP PF12851.7 KFP03872.1 - 3e-74 250.4 0.0 3e-74 250.4 0.0 2.6 2 1 0 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily zf-CXXC PF02008.20 KFP03872.1 - 1.5e-05 24.9 28.8 7.3e-05 22.7 28.8 2.3 1 0 0 1 1 1 1 CXXC zinc finger domain GUCT PF08152.12 KFP03873.1 - 3.7e-33 113.7 0.0 6.7e-33 112.9 0.0 1.4 1 0 0 1 1 1 1 GUCT (NUC152) domain Helicase_C PF00271.31 KFP03873.1 - 6.9e-26 90.8 0.0 6e-25 87.8 0.0 2.5 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KFP03873.1 - 0.0068 15.7 0.0 0.023 13.9 0.0 1.8 1 1 1 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase GUCT PF08152.12 KFP03874.1 - 1.3e-32 112.0 0.0 7.4e-32 109.5 0.0 2.1 2 0 0 2 2 2 1 GUCT (NUC152) domain Helicase_C PF00271.31 KFP03874.1 - 3.3e-25 88.6 0.0 7.6e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KFP03874.1 - 0.0036 16.5 0.0 0.0072 15.6 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase KBP_C PF12309.8 KFP03875.1 - 1.5e-128 429.3 12.4 1.5e-128 429.3 12.4 2.2 2 0 0 2 2 2 1 KIF-1 binding protein C terminal AbiJ_NTD5 PF18865.1 KFP03875.1 - 0.0094 15.7 0.0 0.031 14.1 0.0 1.9 1 0 0 1 1 1 1 AbiJ N-terminal domain 5 TPR_7 PF13176.6 KFP03875.1 - 0.015 15.3 10.2 1.8 8.8 0.6 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFP03875.1 - 0.044 13.6 0.5 0.044 13.6 0.5 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat RGS PF00615.19 KFP03875.1 - 0.13 12.6 0.3 0.13 12.6 0.3 3.0 3 0 0 3 3 3 0 Regulator of G protein signaling domain TPR_12 PF13424.6 KFP03875.1 - 0.67 10.3 12.3 1.3 9.4 1.9 4.7 5 1 0 5 5 5 0 Tetratricopeptide repeat Serglycin PF04360.12 KFP03876.1 - 2.6e-27 95.6 0.0 2.7e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 Serglycin Vps26 PF03643.15 KFP03877.1 - 1.4e-132 440.8 6.4 1.6e-132 440.6 6.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KFP03877.1 - 0.0038 17.3 0.2 0.28 11.2 0.0 3.0 2 1 1 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KFP03877.1 - 0.0043 17.5 0.2 0.065 13.7 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Suv3_N PF18114.1 KFP03878.1 - 1.1e-34 119.0 1.0 1.9e-34 118.3 0.3 1.8 2 0 0 2 2 2 1 Suv3 helical N-terminal domain Suv3_C_1 PF18147.1 KFP03878.1 - 6e-16 58.0 0.2 1.1e-15 57.1 0.2 1.5 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 SUV3_C PF12513.8 KFP03878.1 - 1.8e-15 56.6 0.1 4.5e-15 55.3 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 KFP03878.1 - 2.1e-11 44.2 0.0 4.6e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Hexokinase_2 PF03727.16 KFP03879.1 - 1.6e-168 558.1 1.2 6.5e-89 297.5 0.2 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.21 KFP03879.1 - 9.8e-136 449.9 0.0 2e-70 236.8 0.0 2.3 2 0 0 2 2 2 2 Hexokinase CAS_CSE1 PF03378.15 KFP03879.1 - 0.025 13.1 0.0 0.45 8.9 0.0 2.6 3 0 0 3 3 3 0 CAS/CSE protein, C-terminus CSD PF00313.22 KFP03879.1 - 0.16 11.8 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain Hexokinase_2 PF03727.16 KFP03880.1 - 1.6e-170 564.6 0.9 1.5e-86 289.8 0.3 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.21 KFP03880.1 - 2.1e-142 471.7 0.1 1.5e-71 240.4 0.0 2.3 2 0 0 2 2 2 2 Hexokinase CSD PF00313.22 KFP03880.1 - 0.0035 17.2 0.0 0.19 11.6 0.0 2.7 2 0 0 2 2 2 1 'Cold-shock' DNA-binding domain 7tm_1 PF00001.21 KFP03881.1 - 5e-57 193.2 21.7 6.2e-57 192.9 21.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP03881.1 - 4.2e-08 32.9 24.6 5.4e-08 32.5 24.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Git3 PF11710.8 KFP03881.1 - 0.00032 20.6 6.3 0.00032 20.6 6.3 2.9 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7tm_4 PF13853.6 KFP03881.1 - 0.0021 17.8 22.9 0.0036 17.1 22.9 1.4 1 1 0 1 1 1 1 Olfactory receptor Tetraspanin PF00335.20 KFP03882.1 - 2.3e-47 161.6 8.0 2.8e-47 161.4 8.0 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF2206 PF09971.9 KFP03882.1 - 0.96 8.1 5.3 1.5 7.5 5.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Macro PF01661.21 KFP03883.1 - 6.6e-27 93.9 0.1 1.1e-26 93.2 0.1 1.4 1 0 0 1 1 1 1 Macro domain Histone_H2A_C PF16211.5 KFP03883.1 - 1.6e-16 59.7 0.6 1.6e-16 59.7 0.6 2.5 3 0 0 3 3 3 1 C-terminus of histone H2A Histone PF00125.24 KFP03883.1 - 7.8e-13 48.9 6.2 4.5e-12 46.5 0.0 2.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFP03883.1 - 0.0062 16.8 0.0 0.017 15.4 0.0 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Clp_N PF02861.20 KFP03883.1 - 0.069 13.3 0.2 0.49 10.6 0.0 2.5 3 0 0 3 3 3 0 Clp amino terminal domain, pathogenicity island component DUF1764 PF08576.10 KFP03883.1 - 0.13 13.1 3.9 0.34 11.8 3.9 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Sulfotransfer_1 PF00685.27 KFP03884.1 - 2.6e-49 168.1 0.0 3.4e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP03884.1 - 8.4e-10 39.4 0.1 3.1e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 Sulfotransferase family SapB_1 PF05184.15 KFP03885.1 - 7.2e-44 147.3 24.6 1.9e-13 50.1 0.8 5.7 5 0 0 5 5 5 4 Saposin-like type B, region 1 SapB_2 PF03489.17 KFP03885.1 - 2.6e-42 142.6 46.8 1.1e-11 44.6 2.4 6.1 7 0 0 7 7 7 4 Saposin-like type B, region 2 SapA PF02199.15 KFP03885.1 - 3.2e-16 59.3 9.5 3.2e-16 59.3 9.5 4.0 4 0 0 4 4 4 2 Saposin A-type domain TLE_N PF03920.15 KFP03885.1 - 0.0025 17.9 5.3 0.049 13.7 0.2 2.9 3 1 0 3 3 3 2 Groucho/TLE N-terminal Q-rich domain DUF4451 PF14616.6 KFP03885.1 - 5.1 7.3 10.6 19 5.5 0.1 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4451) DUF3456 PF11938.8 KFP03885.1 - 7.4 7.1 23.5 21 5.6 0.5 6.2 4 3 1 6 6 6 0 TLR4 regulator and MIR-interacting MSAP SapB_1 PF05184.15 KFP03886.1 - 5.3e-22 77.5 11.2 1.1e-12 47.6 2.9 2.5 2 0 0 2 2 2 2 Saposin-like type B, region 1 SapB_2 PF03489.17 KFP03886.1 - 5.4e-16 58.4 2.1 9.1e-10 38.5 0.5 3.0 2 0 0 2 2 2 2 Saposin-like type B, region 2 Helicase_C_3 PF13625.6 KFP03886.1 - 0.023 14.8 0.0 0.062 13.4 0.0 1.6 2 0 0 2 2 2 0 Helicase conserved C-terminal domain SFTA2 PF15210.6 KFP03886.1 - 0.045 13.7 0.4 3.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Surfactant-associated protein 2 Cadherin PF00028.17 KFP03887.1 - 0 1470.3 40.6 6.4e-22 77.8 0.1 27.3 27 0 0 27 27 27 27 Cadherin domain Cadherin_2 PF08266.12 KFP03887.1 - 8.9e-26 89.6 0.0 0.35 10.7 0.0 15.3 17 0 0 17 17 17 7 Cadherin-like Cadherin_3 PF16184.5 KFP03887.1 - 5.5e-20 71.4 39.3 0.025 14.6 0.1 20.2 24 0 0 24 24 24 9 Cadherin-like RET_CLD1 PF17756.1 KFP03887.1 - 8.6e-12 45.4 0.0 1.3 9.3 0.0 9.7 11 0 0 11 11 11 3 RET Cadherin like domain 1 SusE PF14292.6 KFP03887.1 - 0.0077 16.5 9.6 1.4 9.2 0.0 7.4 9 0 0 9 9 9 1 SusE outer membrane protein ig PF00047.25 KFP03888.1 - 9.1e-07 29.0 0.4 2.3e-05 24.5 0.4 2.2 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP03888.1 - 1.5e-06 28.3 0.2 9.3e-06 25.8 0.2 2.0 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP03888.1 - 3.4e-05 24.4 0.1 0.00021 21.8 0.1 2.2 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP03888.1 - 6.1e-05 23.3 0.1 0.29 11.5 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP03888.1 - 0.0075 16.3 0.0 2.9 8.0 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Nucleoside_tran PF01733.18 KFP03890.1 - 1.8e-68 231.2 8.4 1.8e-68 231.2 8.4 2.1 1 1 1 2 2 2 1 Nucleoside transporter DUF4191 PF13829.6 KFP03890.1 - 3.3 7.0 4.3 92 2.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) UPA PF17217.3 KFP03891.1 - 3.5e-72 240.8 0.0 6e-72 240.1 0.0 1.4 1 0 0 1 1 1 1 UPA domain ZU5 PF00791.20 KFP03891.1 - 6.9e-32 109.7 0.0 1.5e-31 108.6 0.0 1.6 1 0 0 1 1 1 1 ZU5 domain Death PF00531.22 KFP03891.1 - 1.2e-14 54.2 0.2 2.3e-14 53.3 0.2 1.5 1 0 0 1 1 1 1 Death domain Ig_3 PF13927.6 KFP03891.1 - 3.6e-11 43.5 0.0 1.7e-07 31.7 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain TSP_1 PF00090.19 KFP03891.1 - 7e-11 42.2 26.9 1.9e-07 31.2 9.9 2.8 2 0 0 2 2 2 2 Thrombospondin type 1 domain I-set PF07679.16 KFP03891.1 - 2.5e-10 40.3 0.0 4.3e-09 36.3 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 KFP03891.1 - 1.4e-06 28.4 0.0 4.1e-05 23.7 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFP03891.1 - 1.7e-05 25.1 0.0 0.00041 20.6 0.0 2.8 2 0 0 2 2 2 1 Immunoglobulin domain Pterin_4a PF01329.19 KFP03892.1 - 6.8e-32 109.5 0.0 7.6e-32 109.3 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Pyridoxal_deC PF00282.19 KFP03893.1 - 8.8e-19 67.5 0.0 1.6e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KFP03893.1 - 2.3e-13 49.9 0.0 1.4e-12 47.2 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFP03893.1 - 0.016 14.5 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase SepSecS PF05889.13 KFP03893.1 - 0.094 11.4 0.0 0.25 10.0 0.0 1.7 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Vitellogenin_N PF01347.22 KFP03894.1 - 1.1e-11 43.9 0.0 1.6e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Lipoprotein amino terminal region DUF1943 PF09172.11 KFP03894.1 - 1.5e-06 27.7 0.4 5.5e-06 25.8 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1943) Pep_M12B_propep PF01562.19 KFP03895.1 - 9.1e-31 107.0 0.0 1.9e-30 105.9 0.0 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide TSP_1 PF00090.19 KFP03895.1 - 7.8e-24 83.6 57.8 1.4e-11 44.4 5.7 6.0 5 0 0 5 5 5 4 Thrombospondin type 1 domain ADAM_spacer1 PF05986.14 KFP03895.1 - 5.1e-22 78.1 0.1 8.2e-22 77.4 0.1 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 ADAM_CR_2 PF17771.1 KFP03895.1 - 1.4e-20 73.5 17.1 2.7e-20 72.6 6.1 5.2 5 0 0 5 5 4 2 ADAM cysteine-rich domain Reprolysin PF01421.19 KFP03895.1 - 1.9e-20 73.7 0.0 4e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 KFP03895.1 - 1e-15 58.4 0.8 2.2e-15 57.4 0.8 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFP03895.1 - 6.1e-10 39.7 0.2 1.2e-09 38.7 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFP03895.1 - 4.4e-09 36.5 0.3 8e-09 35.7 0.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP03895.1 - 6.9e-07 29.1 0.2 1.4e-06 28.1 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like PLAC PF08686.11 KFP03895.1 - 0.0017 19.1 5.8 0.0017 19.1 5.8 3.0 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain Peptidase_M10 PF00413.24 KFP03895.1 - 0.003 17.4 0.2 0.0053 16.6 0.2 1.5 1 0 0 1 1 1 1 Matrixin zf-RING_5 PF14634.6 KFP03895.1 - 0.0093 15.9 2.6 0.092 12.7 2.6 2.9 1 0 0 1 1 1 1 zinc-RING finger domain DUF4953 PF16313.5 KFP03895.1 - 0.097 11.9 0.2 0.15 11.2 0.2 1.2 1 0 0 1 1 1 0 Met-zincin PTPlike_phytase PF14566.6 KFP03896.1 - 4e-82 273.9 0.0 4.6e-40 137.3 0.1 2.6 2 0 0 2 2 2 2 Inositol hexakisphosphate Y_phosphatase PF00102.27 KFP03896.1 - 0.00037 20.1 0.0 0.2 11.2 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFP03896.1 - 0.018 15.0 0.0 0.4 10.6 0.0 2.3 2 0 0 2 2 2 0 Tyrosine phosphatase family HTH_48 PF17906.1 KFP03896.1 - 0.11 12.6 0.1 0.37 11.0 0.1 1.9 1 0 0 1 1 1 0 HTH domain in Mos1 transposase eIF_4EBP PF05456.11 KFP03897.1 - 6.9e-24 84.0 0.0 7.5e-24 83.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) LRR_8 PF13855.6 KFP03898.1 - 3.8e-17 61.8 3.1 2e-08 33.9 3.7 2.7 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KFP03898.1 - 3.8e-14 52.6 1.6 0.00036 20.9 1.2 4.0 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP03898.1 - 4.4e-08 32.6 3.6 0.53 11.0 0.2 5.7 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 KFP03898.1 - 1.2e-06 28.1 2.6 4.7 7.5 0.0 5.3 5 0 0 5 5 5 3 Leucine Rich repeat LRR_9 PF14580.6 KFP03898.1 - 4.6e-05 23.0 0.3 0.00012 21.7 0.2 1.6 1 1 0 1 1 1 1 Leucine-rich repeat 7tm_1 PF00001.21 KFP03899.1 - 1.8e-55 188.1 15.5 1.8e-55 188.1 15.5 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP03899.1 - 4.7e-09 36.0 14.0 6.6e-09 35.5 14.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP03899.1 - 5.8e-05 23.0 14.0 9.9e-05 22.2 14.0 1.4 1 1 0 1 1 1 1 Olfactory receptor DUF3382 PF11862.8 KFP03899.1 - 0.01 16.1 0.7 1.1 9.6 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) Pyrophosphatase PF00719.19 KFP03900.1 - 2.4e-61 206.2 0.7 3e-61 205.9 0.7 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Arf PF00025.21 KFP03901.1 - 1.2e-63 213.7 0.0 1.4e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFP03901.1 - 2.7e-09 36.7 0.0 3.4e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFP03901.1 - 1.8e-08 33.9 0.1 3.6e-06 26.4 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KFP03901.1 - 6.2e-08 32.9 0.0 1.3e-07 31.9 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP03901.1 - 5.5e-07 29.3 0.0 6.3e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KFP03901.1 - 6.7e-06 26.2 0.0 9.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP03901.1 - 0.0005 19.7 0.0 0.0051 16.4 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Metalloenzyme PF01676.18 KFP03901.1 - 0.0033 16.8 0.0 0.03 13.7 0.0 1.9 1 1 1 2 2 2 1 Metalloenzyme superfamily Gtr1_RagA PF04670.12 KFP03901.1 - 0.015 14.7 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SPARC_Ca_bdg PF10591.9 KFP03902.1 - 1.7e-20 73.4 0.2 3.2e-20 72.6 0.0 1.5 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Thyroglobulin_1 PF00086.18 KFP03902.1 - 2.1e-16 59.3 0.9 2.1e-16 59.3 0.9 1.7 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat EF-hand_7 PF13499.6 KFP03902.1 - 6.6e-05 23.3 0.0 0.00017 21.9 0.0 1.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP03902.1 - 0.00094 18.9 0.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KFP03902.1 - 0.0018 17.7 0.0 0.075 12.6 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_10 PF14788.6 KFP03902.1 - 0.011 15.6 0.1 0.15 11.9 0.0 2.1 1 1 1 2 2 2 0 EF hand EF-hand_5 PF13202.6 KFP03902.1 - 0.03 13.8 0.0 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 KFP03902.1 - 0.084 12.7 0.0 3 7.8 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair AKAP7_NLS PF10469.9 KFP03903.1 - 9.2e-59 198.8 0.2 1.1e-58 198.5 0.2 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain KH_1 PF00013.29 KFP03903.1 - 1.4e-10 40.8 1.2 3.3e-10 39.6 1.2 1.6 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 KFP03903.1 - 0.026 14.3 0.1 0.056 13.3 0.1 1.5 1 0 0 1 1 1 0 KH domain ANAPC16 PF17256.2 KFP03904.1 - 2.2e-56 188.2 0.1 2.6e-56 188.0 0.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 16 DUF2110 PF09883.9 KFP03904.1 - 0.078 12.6 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) RTP801_C PF07809.11 KFP03905.1 - 6e-38 129.4 0.0 7.6e-38 129.1 0.0 1.1 1 0 0 1 1 1 1 RTP801 C-terminal region DUF1977 PF09320.11 KFP03906.1 - 2.7e-28 98.3 0.2 4.9e-28 97.5 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 KFP03906.1 - 3.9e-27 94.2 0.9 5.9e-27 93.6 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 KFP03906.1 - 0.011 15.6 0.0 0.26 11.2 0.0 2.3 2 0 0 2 2 2 0 A repeated domain in UCH-protein MCU PF04678.13 KFP03908.1 - 5e-69 231.9 1.4 6.1e-69 231.6 1.4 1.1 1 0 0 1 1 1 1 Mitochondrial calcium uniporter DUF2960 PF11173.8 KFP03908.1 - 0.018 15.5 0.0 0.064 13.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2960) Zona_pellucida PF00100.23 KFP03909.1 - 9.3e-47 160.0 0.6 2.7e-46 158.5 0.2 1.9 2 0 0 2 2 2 1 Zona pellucida-like domain FXa_inhibition PF14670.6 KFP03909.1 - 3.4e-17 62.4 30.7 5.4e-11 42.6 11.4 4.7 6 0 0 6 6 6 2 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFP03909.1 - 1.1e-06 28.5 17.1 0.0028 17.5 0.7 4.4 3 0 0 3 3 3 3 Complement Clr-like EGF-like EGF_3 PF12947.7 KFP03909.1 - 0.022 14.9 6.4 0.022 14.9 6.4 4.7 5 0 0 5 5 5 0 EGF domain PLA2G12 PF06951.11 KFP03910.1 - 4.7e-89 297.1 8.4 5.2e-89 297.0 8.4 1.0 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) P4Ha_N PF08336.11 KFP03911.1 - 1.2e-40 138.6 1.3 1.5e-40 138.4 0.1 1.7 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 KFP03911.1 - 4.8e-16 59.4 0.0 1e-15 58.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KFP03911.1 - 1.2e-08 35.4 0.0 2.3e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fis1_TPR_C PF14853.6 KFP03911.1 - 0.0012 18.9 0.5 0.013 15.6 0.5 2.6 1 1 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 KFP03911.1 - 0.05 13.7 0.8 0.35 11.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFP03911.1 - 0.072 13.9 0.2 0.3 12.0 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat NUDIX PF00293.28 KFP03912.1 - 4.6e-15 55.8 0.0 7.7e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KFP03912.1 - 1.4e-10 41.7 0.0 2.6e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KFP03912.1 - 2.8e-08 33.3 0.3 5.7e-08 32.3 0.3 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain SGT1 PF07093.11 KFP03913.1 - 3.6e-194 646.5 0.7 4.2e-194 646.3 0.7 1.0 1 0 0 1 1 1 1 SGT1 protein PI3K_1B_p101 PF10486.9 KFP03913.1 - 8.8 4.0 7.7 12 3.6 7.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF3719 PF12516.8 KFP03914.1 - 7.2e-21 73.7 0.1 1.9e-20 72.3 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3719) FAM220 PF15487.6 KFP03914.1 - 0.52 9.9 6.3 0.76 9.4 1.4 2.6 2 1 1 3 3 3 0 FAM220 family NAT PF04768.13 KFP03915.1 - 0.11 12.1 0.5 0.29 10.8 0.4 1.6 1 1 1 2 2 2 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase DUF1266 PF06889.11 KFP03915.1 - 0.13 12.3 3.0 0.12 12.4 1.3 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1266) HrpJ PF07201.11 KFP03915.1 - 1.5 9.2 8.6 1.5 9.1 7.4 1.5 2 0 0 2 2 2 0 HrpJ-like domain HMG_box PF00505.19 KFP03916.1 - 4.6e-29 100.6 12.3 8.1e-21 74.2 5.3 3.1 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP03916.1 - 4.4e-17 62.4 21.6 5.6e-10 39.7 5.2 3.0 3 1 0 3 3 3 2 HMG-box domain YABBY PF04690.13 KFP03916.1 - 0.0028 18.2 0.3 0.0028 18.2 0.3 2.9 1 1 2 3 3 3 1 YABBY protein DUF1612 PF07756.12 KFP03916.1 - 0.085 13.1 5.1 1.3 9.2 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1612) Inhibitor_I9 PF05922.16 KFP03916.1 - 0.19 12.4 0.2 0.19 12.4 0.2 2.1 2 1 0 2 2 2 0 Peptidase inhibitor I9 COX4 PF02936.14 KFP03916.1 - 0.27 11.3 8.7 0.35 10.9 0.2 2.5 2 1 0 2 2 2 0 Cytochrome c oxidase subunit IV DUF4055 PF13264.6 KFP03916.1 - 0.53 10.4 7.7 1.7 8.8 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) UQ_con PF00179.26 KFP03917.1 - 1.4e-52 177.0 0.0 1.6e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFP03917.1 - 0.0015 18.8 0.0 0.0022 18.3 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KFP03917.1 - 0.0063 16.2 0.0 0.0074 16.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KFP03917.1 - 0.09 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 UEV domain zf-CDGSH PF09360.10 KFP03918.1 - 6.6e-10 39.1 0.3 1.2e-09 38.2 0.3 1.5 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type MitoNEET_N PF10660.9 KFP03918.1 - 7.9e-08 32.2 0.3 1.1e-07 31.8 0.3 1.2 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus CHDNT PF08073.12 KFP03918.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 CHDNT (NUC034) domain IPK PF03770.16 KFP03919.1 - 7e-67 225.1 0.3 1e-66 224.6 0.3 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase RVT_1 PF00078.27 KFP03922.1 - 0.068 12.7 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) IRF PF00605.17 KFP03923.1 - 3.3e-18 65.9 0.0 3.5e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor IRF-3 PF10401.9 KFP03924.1 - 3e-17 63.0 0.0 4.7e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 Xpo1 PF08389.12 KFP03926.1 - 7.1e-25 87.8 0.5 1.1e-24 87.2 0.5 1.3 1 0 0 1 1 1 1 Exportin 1-like protein CCM2_C PF16545.5 KFP03927.1 - 2e-47 159.8 0.3 3.6e-47 159.0 0.3 1.4 1 0 0 1 1 1 1 Cerebral cavernous malformation protein, harmonin-homology PID PF00640.23 KFP03927.1 - 0.011 15.7 0.0 0.044 13.8 0.0 1.9 1 1 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) DUF1722 PF08349.11 KFP03927.1 - 0.027 14.7 0.1 0.071 13.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) HTH_48 PF17906.1 KFP03927.1 - 0.18 11.9 0.0 0.47 10.6 0.0 1.7 1 0 0 1 1 1 0 HTH domain in Mos1 transposase FAST_1 PF06743.15 KFP03928.1 - 3.9e-05 23.5 0.0 5.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 FAST kinase-like protein, subdomain 1 BORCS8 PF10167.9 KFP03929.1 - 1.1e-26 92.9 0.1 1.2e-26 92.8 0.1 1.0 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 8 TMEM71 PF15121.6 KFP03929.1 - 0.076 12.7 0.0 0.077 12.7 0.0 1.1 1 0 0 1 1 1 0 TMEM71 protein family F5_F8_type_C PF00754.25 KFP03930.1 - 3e-05 24.2 0.0 4.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain ApeA_NTD1 PF18862.1 KFP03930.1 - 0.016 14.8 0.0 0.021 14.4 0.0 1.1 1 0 0 1 1 1 0 ApeA N-terminal domain 1 ANAPC10 PF03256.16 KFP03930.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) Xlink PF00193.17 KFP03931.1 - 3.2e-48 162.1 1.7 9.3e-34 115.7 0.0 2.2 2 0 0 2 2 2 2 Extracellular link domain V-set PF07686.17 KFP03931.1 - 1.1e-10 41.6 0.0 2e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP03931.1 - 2.1e-07 31.4 0.0 4.6e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP03931.1 - 2.9e-07 30.5 0.0 6.1e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFP03931.1 - 2.8e-06 27.4 0.0 7.8e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Chordopox_A33R PF05966.12 KFP03931.1 - 6.8e-06 25.5 0.2 0.0038 16.5 0.0 2.1 2 0 0 2 2 2 2 Chordopoxvirus A33R protein Ig_2 PF13895.6 KFP03931.1 - 2.5e-05 24.5 0.0 0.00011 22.4 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin domain Lectin_C PF00059.21 KFP03931.1 - 0.0093 16.7 0.8 2.6 8.8 0.1 2.3 2 0 0 2 2 2 2 Lectin C-type domain V-set_CD47 PF08204.11 KFP03931.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.6 1 1 0 1 1 1 0 CD47 immunoglobulin-like domain DUF2781 PF10914.8 KFP03932.1 - 8.6e-11 42.4 7.1 1.2e-10 42.0 3.5 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2781) PRIMA1 PF16101.5 KFP03932.1 - 0.015 15.4 0.1 0.028 14.4 0.1 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 KFP03932.1 - 0.2 11.1 0.1 0.25 10.8 0.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Surp PF01805.20 KFP03933.1 - 6.3e-29 99.7 3.5 2.6e-15 56.1 0.1 2.8 2 0 0 2 2 2 2 Surp module G-patch PF01585.23 KFP03933.1 - 3.4e-15 55.7 2.8 8.3e-15 54.4 2.8 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFP03933.1 - 3.9e-07 30.1 1.7 4.2e-06 26.8 0.4 2.8 2 0 0 2 2 2 1 G-patch domain RtcB PF01139.17 KFP03933.1 - 0.034 13.3 1.4 0.068 12.3 1.4 1.4 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB Cohesin_load PF10345.9 KFP03934.1 - 6.7e-123 411.2 13.8 7.6e-123 411.0 13.8 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.6 KFP03934.1 - 1.5e-09 38.0 12.0 0.0017 18.6 0.1 5.7 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFP03934.1 - 1.3e-07 31.1 7.3 0.24 11.6 0.2 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP03934.1 - 9e-07 28.6 16.0 0.00057 19.4 2.4 3.9 2 1 2 4 4 4 2 MalT-like TPR region TPR_10 PF13374.6 KFP03934.1 - 2.2e-06 27.3 0.1 3.9 7.5 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP03934.1 - 0.00012 22.0 5.8 1.4 9.3 0.1 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP03934.1 - 0.00079 19.9 4.7 0.018 15.5 0.1 4.0 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFP03934.1 - 0.0031 17.3 5.1 1.8 8.5 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat HemY_N PF07219.13 KFP03934.1 - 0.0039 17.4 0.0 0.089 13.0 0.0 2.8 2 0 0 2 2 2 1 HemY protein N-terminus TPR_11 PF13414.6 KFP03934.1 - 0.098 12.4 0.1 6.9 6.4 0.0 3.4 3 0 0 3 3 3 0 TPR repeat DUF4110 PF13422.6 KFP03934.1 - 0.14 12.2 0.0 22 5.2 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4110) ANAPC3 PF12895.7 KFP03934.1 - 0.51 10.6 8.2 4.4 7.6 0.6 4.1 3 2 3 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 P66_CC PF16563.5 KFP03935.1 - 4.8e-20 70.9 11.4 1.4e-19 69.4 11.4 1.9 1 0 0 1 1 1 1 Coiled-coil and interaction region of P66A and P66B with MBD2 GATA PF00320.27 KFP03935.1 - 2e-07 30.5 8.1 2e-07 30.5 8.1 2.2 2 0 0 2 2 2 1 GATA zinc finger DUF2299 PF10061.9 KFP03935.1 - 0.14 11.9 0.7 0.36 10.6 0.7 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) Ig_3 PF13927.6 KFP03936.1 - 2e-12 47.5 0.1 4.1e-12 46.5 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP03936.1 - 6.9e-10 39.1 0.1 1.3e-09 38.2 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain CarboxypepD_reg PF13620.6 KFP03936.1 - 2.1e-08 34.3 0.1 0.0011 19.1 0.0 2.9 2 0 0 2 2 2 2 Carboxypeptidase regulatory-like domain TSP_1 PF00090.19 KFP03936.1 - 7e-08 32.6 11.7 2.2e-07 31.0 11.7 1.9 1 0 0 1 1 1 1 Thrombospondin type 1 domain CarbopepD_reg_2 PF13715.6 KFP03936.1 - 2.5e-06 27.4 0.0 0.00023 21.1 0.0 2.4 2 0 0 2 2 2 1 CarboxypepD_reg-like domain I-set PF07679.16 KFP03936.1 - 4.4e-06 26.7 0.0 7.9e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFP03936.1 - 0.002 18.3 0.0 0.0048 17.0 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP03936.1 - 0.15 12.3 0.0 6.7 6.9 0.0 2.5 1 1 1 2 2 2 0 Immunoglobulin V-set domain DDA1 PF10172.9 KFP03937.1 - 1.8e-30 105.0 0.1 2.7e-30 104.4 0.1 1.3 1 0 0 1 1 1 1 Det1 complexing ubiquitin ligase zf-H2C2_2 PF13465.6 KFP03938.1 - 1.8e-24 85.0 10.9 1.8e-11 43.9 0.2 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFP03938.1 - 2.2e-18 65.6 11.9 1.3e-07 31.6 0.1 3.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP03938.1 - 2.2e-12 46.7 10.0 6.2e-05 23.5 0.1 3.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFP03938.1 - 1.2e-10 40.9 4.0 0.00037 20.2 0.3 3.0 3 0 0 3 3 3 2 zinc-finger C2H2-type zinc_ribbon_9 PF14369.6 KFP03938.1 - 8.7e-09 35.5 6.9 0.022 15.0 0.1 3.0 3 0 0 3 3 3 2 zinc-ribbon zf-Di19 PF05605.12 KFP03938.1 - 3.7e-08 33.5 4.0 9e-05 22.7 0.0 2.4 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KFP03938.1 - 9.9e-08 32.1 0.0 0.025 14.9 0.0 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KFP03938.1 - 1e-06 28.7 9.8 0.00026 21.0 2.7 2.3 1 1 1 2 2 2 2 Zinc ribbon domain zf-H2C2_5 PF13909.6 KFP03938.1 - 2e-06 27.4 2.3 0.0017 18.0 0.1 3.5 4 0 0 4 4 3 2 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 KFP03938.1 - 1.6e-05 24.6 10.0 0.059 13.3 0.1 3.2 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KFP03938.1 - 1.7e-05 24.3 2.6 0.3 10.7 0.2 3.2 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger Zn_ribbon_SprT PF17283.2 KFP03938.1 - 2.7e-05 24.0 9.6 0.011 15.6 1.5 3.5 1 1 1 2 2 2 2 SprT-like zinc ribbon domain zf-ribbon_3 PF13248.6 KFP03938.1 - 5.4e-05 22.5 12.5 0.11 12.0 0.3 3.2 3 0 0 3 3 3 3 zinc-ribbon domain zf-C2H2_6 PF13912.6 KFP03938.1 - 6e-05 22.9 10.9 0.07 13.2 0.7 3.4 3 1 0 3 3 3 2 C2H2-type zinc finger DZR PF12773.7 KFP03938.1 - 0.00014 21.8 3.7 0.0033 17.4 3.7 2.3 1 1 0 1 1 1 1 Double zinc ribbon zinc_ribbon_4 PF13717.6 KFP03938.1 - 0.00056 19.8 5.1 3.4 7.7 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain ADK_lid PF05191.14 KFP03938.1 - 0.00084 19.3 2.1 0.072 13.1 0.2 2.6 2 1 0 2 2 2 1 Adenylate kinase, active site lid HypA PF01155.19 KFP03938.1 - 0.00093 19.2 0.8 0.0054 16.7 0.1 2.0 1 1 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sgf11 PF08209.11 KFP03938.1 - 0.0016 17.9 5.3 1.6 8.4 0.1 3.3 3 0 0 3 3 3 1 Sgf11 (transcriptional regulation protein) zf-C2H2_9 PF16293.5 KFP03938.1 - 0.0017 18.1 0.2 1.6 8.6 0.0 2.7 1 1 2 3 3 3 1 C2H2 type zinc-finger (1 copy) zf-HIT PF04438.16 KFP03938.1 - 0.0021 17.9 9.7 0.14 12.1 0.4 3.1 3 0 0 3 3 3 2 HIT zinc finger Zn-C2H2_12 PF18112.1 KFP03938.1 - 0.0032 17.9 2.5 13 6.4 0.0 3.3 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain IBR PF01485.21 KFP03938.1 - 0.0033 17.6 2.3 0.071 13.3 2.3 2.0 1 1 0 1 1 1 1 IBR domain, a half RING-finger domain zf-met PF12874.7 KFP03938.1 - 0.004 17.5 4.3 1.7 9.2 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type CpXC PF14353.6 KFP03938.1 - 0.0044 17.1 4.7 1.8 8.6 0.3 3.0 1 1 1 2 2 2 1 CpXC protein DUF1610 PF07754.11 KFP03938.1 - 0.0048 16.8 21.3 0.36 10.8 0.1 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF1610) zf-RING_7 PF02591.15 KFP03938.1 - 0.0061 16.7 8.9 1.9 8.7 0.1 3.1 3 0 0 3 3 3 0 C4-type zinc ribbon domain Ogr_Delta PF04606.12 KFP03938.1 - 0.0068 16.4 8.9 0.012 15.5 1.1 2.6 1 1 0 2 2 2 1 Ogr/Delta-like zinc finger C1_4 PF07975.12 KFP03938.1 - 0.0069 16.6 1.2 1 9.6 1.1 2.3 1 1 1 2 2 2 1 TFIIH C1-like domain zinc_ribbon_15 PF17032.5 KFP03938.1 - 0.0086 16.8 1.5 0.1 13.3 1.5 2.0 1 1 0 1 1 1 1 zinc-ribbon family FYDLN_acid PF09538.10 KFP03938.1 - 0.009 16.7 2.4 3.2 8.5 0.2 3.0 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) YacG PF03884.14 KFP03938.1 - 0.011 15.5 4.6 11 5.9 0.1 3.2 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG zinc_ribbon_2 PF13240.6 KFP03938.1 - 0.017 14.8 16.9 1.2 9.0 0.8 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_8 PF15909.5 KFP03938.1 - 0.018 15.3 0.5 0.025 14.9 0.5 1.3 1 0 0 1 1 1 0 C2H2-type zinc ribbon TRAF6_Z2 PF18048.1 KFP03938.1 - 0.018 15.1 1.9 6.7 6.9 0.0 3.2 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 XPA_N PF01286.18 KFP03938.1 - 0.019 15.0 3.6 7.9 6.6 0.3 3.1 3 0 0 3 3 3 0 XPA protein N-terminal DUF2225 PF09986.9 KFP03938.1 - 0.019 14.7 0.5 1.8 8.2 0.0 2.6 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) HNH PF01844.23 KFP03938.1 - 0.022 15.0 4.0 2.8 8.2 0.0 3.0 3 0 0 3 3 3 0 HNH endonuclease Zn_Tnp_IS1595 PF12760.7 KFP03938.1 - 0.022 14.7 9.1 0.47 10.5 2.6 2.6 1 1 1 2 2 2 0 Transposase zinc-ribbon domain YhfH PF14149.6 KFP03938.1 - 0.022 14.7 7.4 2.3 8.3 0.2 3.2 3 0 0 3 3 3 0 YhfH-like protein zf-BED PF02892.15 KFP03938.1 - 0.025 14.6 5.1 0.32 11.1 0.4 2.6 1 1 2 3 3 3 0 BED zinc finger TF_Zn_Ribbon PF08271.12 KFP03938.1 - 0.027 14.0 12.6 0.85 9.2 0.9 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding zf-C2HE PF16278.5 KFP03938.1 - 0.029 14.8 4.2 4.6 7.8 0.2 3.0 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-LYAR PF08790.11 KFP03938.1 - 0.031 14.2 0.8 18 5.4 0.0 3.2 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Rad50_zn_hook PF04423.14 KFP03938.1 - 0.031 14.1 5.0 15 5.5 0.2 3.3 1 1 2 3 3 3 0 Rad50 zinc hook motif zinc-ribbons_6 PF07191.12 KFP03938.1 - 0.031 14.3 1.9 0.14 12.2 1.9 2.0 1 1 0 1 1 1 0 zinc-ribbons TFIIS_C PF01096.18 KFP03938.1 - 0.039 13.8 7.7 4 7.4 0.2 3.1 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) FYVE PF01363.21 KFP03938.1 - 0.045 13.9 1.7 0.47 10.6 1.3 2.2 1 1 0 1 1 1 0 FYVE zinc finger zf-IS66 PF13005.7 KFP03938.1 - 0.048 14.1 5.4 11 6.5 0.0 3.2 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 zinc_ribbon_10 PF10058.9 KFP03938.1 - 0.05 13.3 4.9 2.8 7.7 0.0 2.9 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-AN1 PF01428.16 KFP03938.1 - 0.06 13.5 10.7 0.83 9.9 0.6 3.1 2 1 1 3 3 3 0 AN1-like Zinc finger zf-Mss51 PF13824.6 KFP03938.1 - 0.063 13.4 9.6 1.5 9.0 0.5 2.8 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 FOXP-CC PF16159.5 KFP03938.1 - 0.072 13.7 1.2 8.8 7.0 0.0 2.2 2 0 0 2 2 2 0 FOXP coiled-coil domain C1_1 PF00130.22 KFP03938.1 - 0.074 12.9 1.5 7.9 6.5 0.1 2.6 1 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TerY_C PF15616.6 KFP03938.1 - 0.078 13.1 1.5 0.31 11.2 0.1 1.9 1 1 1 2 2 2 0 TerY-C metal binding domain Cys_rich_CPXG PF14255.6 KFP03938.1 - 0.079 12.9 5.7 9.2 6.3 0.1 3.3 3 0 0 3 3 3 0 Cysteine-rich CPXCG DUF2256 PF10013.9 KFP03938.1 - 0.091 12.9 3.3 31 4.8 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Prok-RING_1 PF14446.6 KFP03938.1 - 0.11 12.5 4.5 19 5.3 0.0 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 DUF3268 PF11672.8 KFP03938.1 - 0.13 12.6 0.9 1.4 9.3 0.1 1.9 1 1 1 2 2 2 0 zinc-finger-containing domain zf-CHY PF05495.12 KFP03938.1 - 0.15 12.6 2.2 18 5.9 0.2 2.4 1 1 0 2 2 2 0 CHY zinc finger zf-RING_5 PF14634.6 KFP03938.1 - 0.16 12.0 3.7 6.7 6.8 0.4 2.6 1 1 1 2 2 2 0 zinc-RING finger domain zf-C2H2_3 PF13878.6 KFP03938.1 - 0.18 11.7 3.2 8.6 6.3 0.0 3.1 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO zf-MYND PF01753.18 KFP03938.1 - 0.22 11.7 3.1 3.5 7.8 3.1 2.3 1 1 0 1 1 1 0 MYND finger zf-LITAF-like PF10601.9 KFP03938.1 - 0.24 11.7 5.0 18 5.7 0.0 3.1 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain zf-CCHC_5 PF14787.6 KFP03938.1 - 0.25 11.1 12.7 2.6 7.8 0.6 3.2 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger HalOD2 PF18547.1 KFP03938.1 - 0.29 11.1 5.4 14 5.7 0.1 3.0 3 0 0 3 3 3 0 Halobacterial output domain 2 zinc_ribbon_5 PF13719.6 KFP03938.1 - 0.29 10.9 5.3 30 4.5 0.3 3.1 3 0 0 3 3 3 0 zinc-ribbon domain PADR1 PF08063.12 KFP03938.1 - 0.33 10.8 7.4 11 5.9 0.1 3.1 3 0 0 3 3 3 0 PADR1 (NUC008) domain OrfB_Zn_ribbon PF07282.11 KFP03938.1 - 0.33 10.9 6.5 2.7 8.0 1.2 2.7 1 1 1 2 2 2 0 Putative transposase DNA-binding domain GAGA PF09237.11 KFP03938.1 - 0.35 10.7 4.3 0.79 9.6 0.2 2.7 1 1 2 3 3 3 0 GAGA factor Ribosomal_L37ae PF01780.19 KFP03938.1 - 0.35 11.0 4.7 9.1 6.4 0.3 2.7 1 1 1 2 2 2 0 Ribosomal L37ae protein family zf-C4_Topoisom PF01396.19 KFP03938.1 - 0.38 10.6 10.6 3.4 7.5 0.5 3.2 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger DUF2321 PF10083.9 KFP03938.1 - 0.47 10.1 2.0 0.74 9.4 2.0 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Nudix_N_2 PF14803.6 KFP03938.1 - 0.53 10.3 7.8 25 4.9 2.6 3.4 2 1 1 3 3 3 0 Nudix N-terminal DUF1272 PF06906.11 KFP03938.1 - 0.63 10.2 8.3 8.5 6.6 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1272) Zn_ribbon_recom PF13408.6 KFP03938.1 - 0.75 10.4 7.2 1.2 9.7 1.6 2.7 1 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Zn_Tnp_IS91 PF14319.6 KFP03938.1 - 0.8 9.8 4.4 6.8 6.8 2.6 2.6 1 1 1 2 2 2 0 Transposase zinc-binding domain zf-trcl PF13451.6 KFP03938.1 - 0.84 9.6 4.1 14 5.6 0.1 2.9 3 0 0 3 3 3 0 Probable zinc-ribbon domain Rubredoxin PF00301.20 KFP03938.1 - 0.85 9.7 8.2 12 6.1 0.1 3.1 3 0 0 3 3 3 0 Rubredoxin DNA_RNApol_7kD PF03604.13 KFP03938.1 - 0.95 9.2 7.8 4.3 7.1 0.1 3.1 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-HYPF PF07503.12 KFP03938.1 - 1.2 9.0 8.2 19 5.2 0.2 3.2 3 0 0 3 3 3 0 HypF finger zf-ISL3 PF14690.6 KFP03938.1 - 1.3 9.7 14.1 15 6.3 1.4 3.9 3 2 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 PhnA_Zn_Ribbon PF08274.12 KFP03938.1 - 1.4 8.9 8.5 13 5.8 0.4 3.2 3 0 0 3 3 3 0 PhnA Zinc-Ribbon DUF35_N PF12172.8 KFP03938.1 - 1.5 8.8 8.8 20 5.2 0.1 3.2 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf_Rg PF17915.1 KFP03938.1 - 1.6 8.2 9.3 5.2 6.5 0.2 3.0 3 0 0 3 3 3 0 Reverse gyrase zinc finger A2L_zn_ribbon PF08792.10 KFP03938.1 - 2.2 8.1 8.3 4.8 7.0 0.1 3.0 3 0 0 3 3 3 0 A2L zinc ribbon domain Opy2 PF09463.10 KFP03938.1 - 2.7 8.4 11.1 10 6.6 0.2 3.1 3 0 0 3 3 3 0 Opy2 protein zf-TFIIB PF13453.6 KFP03938.1 - 3 7.3 8.7 20 4.6 0.3 3.0 2 1 1 3 3 3 0 Transcription factor zinc-finger DUF4764 PF15961.5 KFP03938.1 - 3.5 6.2 5.5 2.2 6.9 3.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4764) zf_C2H2_13 PF18508.1 KFP03938.1 - 3.8 7.2 7.0 16 5.2 0.1 3.1 3 1 0 3 3 3 0 Zinc finger domain zf-NADH-PPase PF09297.11 KFP03938.1 - 4.1 7.2 8.2 25 4.6 0.1 3.2 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain DUF2752 PF10825.8 KFP03938.1 - 6.6 6.9 7.0 23 5.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2752) zf-ACC PF17848.1 KFP03938.1 - 6.7 6.9 12.6 7.3 6.8 1.1 3.3 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain DUF983 PF06170.12 KFP03938.1 - 7.1 7.1 5.0 1e+02 3.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF983) zf-tcix PF14952.6 KFP03938.1 - 7.3 6.3 13.7 8.3 6.1 1.1 3.2 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding DUF3797 PF12677.7 KFP03938.1 - 8.9 6.3 13.1 12 5.8 0.8 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF3797) Rubredoxin_2 PF18073.1 KFP03938.1 - 9.7 6.0 14.9 8.7 6.2 0.4 3.2 3 0 0 3 3 3 0 Rubredoxin metal binding domain UPF0547 PF10571.9 KFP03938.1 - 9.8 6.4 13.5 3.4 7.8 0.6 3.1 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Trypsin PF00089.26 KFP03939.1 - 6.5e-31 107.9 0.1 7.2e-31 107.7 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFP03939.1 - 0.0014 19.6 0.0 0.0017 19.2 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFP03939.1 - 0.0019 18.6 0.2 0.004 17.5 0.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) c-SKI_SMAD_bind PF08782.10 KFP03940.1 - 0.096 12.9 0.6 15 5.9 0.1 2.4 2 0 0 2 2 2 0 c-SKI Smad4 binding domain Peptidase_A21 PF03566.13 KFP03940.1 - 1 7.6 5.3 1.5 7.0 5.0 1.4 1 1 0 1 1 1 0 Peptidase family A21 AP3D1 PF06375.11 KFP03940.1 - 4.6 7.5 21.8 0.11 12.8 10.0 2.6 1 1 1 2 2 2 0 AP-3 complex subunit delta-1 C2 PF00168.30 KFP03941.1 - 1.3e-19 70.3 0.1 1.6e-18 66.9 0.0 2.4 2 0 0 2 2 2 1 C2 domain RBD-FIP PF09457.10 KFP03941.1 - 1.8e-16 59.8 3.0 3.7e-16 58.8 3.0 1.6 1 0 0 1 1 1 1 FIP domain Yae1_N PF09811.9 KFP03942.1 - 5.5e-13 48.4 41.6 0.003 17.2 7.4 4.1 1 1 1 2 2 2 1 Essential protein Yae1, N terminal zf-CCHC PF00098.23 KFP03943.1 - 1.7e-05 24.7 1.6 3.4e-05 23.7 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KFP03943.1 - 0.015 15.0 2.2 0.12 12.1 0.5 2.7 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 KFP03943.1 - 0.033 14.2 0.4 0.061 13.3 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle KH_1 PF00013.29 KFP03943.1 - 0.038 13.8 0.9 0.1 12.5 0.9 1.8 1 1 0 1 1 1 0 KH domain Transglut_C PF00927.22 KFP03945.1 - 6.8e-37 125.8 0.2 1.6e-19 70.0 0.0 2.7 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_N PF00868.20 KFP03945.1 - 7.7e-32 110.1 0.8 1.7e-31 109.0 0.8 1.5 1 0 0 1 1 1 1 Transglutaminase family Transglut_core PF01841.19 KFP03945.1 - 2e-15 57.2 0.2 3.9e-15 56.3 0.2 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily MG2 PF01835.19 KFP03945.1 - 0.00036 20.9 0.1 0.001 19.5 0.1 1.8 1 0 0 1 1 1 1 MG2 domain Transglut_N PF00868.20 KFP03946.1 - 3.1e-29 101.7 0.0 9e-29 100.2 0.0 1.9 1 0 0 1 1 1 1 Transglutaminase family Transglut_C PF00927.22 KFP03946.1 - 6e-27 93.9 0.2 4.1e-14 52.6 0.0 2.6 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 KFP03946.1 - 4e-17 62.7 0.2 1e-16 61.3 0.2 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_N PF00868.20 KFP03947.1 - 1e-32 112.9 0.1 2.7e-32 111.6 0.0 1.8 2 0 0 2 2 2 1 Transglutaminase family Transglut_C PF00927.22 KFP03947.1 - 1.7e-28 98.8 0.4 1.5e-14 54.0 0.1 2.5 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 KFP03947.1 - 1.6e-16 60.7 0.1 4.4e-16 59.3 0.1 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily MG2 PF01835.19 KFP03947.1 - 0.085 13.3 0.0 1.5 9.3 0.0 2.5 2 0 0 2 2 2 0 MG2 domain Transglut_N PF00868.20 KFP03948.1 - 4.2e-32 111.0 0.0 7.8e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase family Transglut_C PF00927.22 KFP03948.1 - 9.4e-28 96.5 0.0 8.8e-16 58.0 0.0 3.4 3 0 0 3 3 3 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 KFP03948.1 - 1.9e-18 67.0 1.1 3.4e-18 66.1 1.1 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily MG2 PF01835.19 KFP03948.1 - 0.0056 17.1 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 MG2 domain GCIP PF13324.6 KFP03949.1 - 4.6e-89 298.5 2.9 5.3e-89 298.3 2.9 1.0 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting AAA_12 PF13087.6 KFP03950.1 - 3.9e-40 137.6 0.0 1.2e-39 136.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFP03950.1 - 7.3e-28 98.1 7.3 1.2e-24 87.6 7.3 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFP03950.1 - 6.3e-11 42.8 2.0 2.9e-09 37.4 2.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFP03950.1 - 2.1e-08 34.2 1.0 0.00017 21.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 KFP03950.1 - 0.00018 20.9 0.6 0.0033 16.7 0.0 3.0 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 KFP03950.1 - 0.0029 17.4 0.8 0.012 15.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KFP03950.1 - 0.0089 16.0 0.0 0.026 14.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KFP03950.1 - 0.012 15.1 0.1 0.038 13.4 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 KFP03950.1 - 0.041 14.1 3.6 0.73 10.1 0.0 3.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KFP03950.1 - 0.13 11.8 1.1 0.64 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain CheB_methylest PF01339.17 KFP03950.1 - 0.17 11.6 0.1 0.39 10.4 0.1 1.6 1 0 0 1 1 1 0 CheB methylesterase AAA PF00004.29 KFP03950.1 - 0.19 12.2 0.1 1.4 9.4 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP-synt_E_2 PF08112.11 KFP03950.1 - 2.1 8.7 4.8 0.55 10.6 0.7 2.1 2 0 0 2 2 1 0 ATP synthase epsilon subunit UvrD-helicase PF00580.21 KFP03950.1 - 6.8 6.1 13.7 1.8 8.0 6.4 3.5 3 1 0 3 3 3 0 UvrD/REP helicase N-terminal domain DEAD PF00270.29 KFP03951.1 - 4.5e-46 156.8 0.3 4.3e-45 153.6 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP03951.1 - 1.5e-29 102.5 0.2 6e-28 97.4 0.1 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP03951.1 - 2.6e-06 27.6 0.0 2.6e-06 27.6 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KFP03951.1 - 0.00058 18.7 3.4 0.11 11.2 0.1 3.5 2 1 1 3 3 3 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 KFP03951.1 - 0.0023 18.2 1.7 0.035 14.4 1.7 2.9 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 KFP03951.1 - 0.07 12.9 2.6 0.26 11.0 0.0 2.7 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family LSM PF01423.22 KFP03952.1 - 0.016 14.9 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 LSM domain DUF3361 PF11841.8 KFP03953.1 - 2.2e-59 199.8 7.0 4.8e-59 198.7 7.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.13 KFP03953.1 - 5.1e-40 137.5 0.3 9e-40 136.7 0.3 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 KFP03953.1 - 1.8e-38 132.1 0.1 8.4e-38 129.9 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain SIL1 PF16782.5 KFP03953.1 - 0.0039 16.4 2.7 0.0099 15.1 2.7 1.7 1 1 0 1 1 1 1 Nucleotide exchange factor SIL1 Cas_CT1975 PF09344.10 KFP03953.1 - 0.051 13.0 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 CT1975-like protein Cadherin PF00028.17 KFP03954.1 - 5.1e-84 276.9 12.0 2.8e-20 72.5 0.1 5.5 5 1 1 6 6 6 5 Cadherin domain Cadherin_C PF01049.17 KFP03954.1 - 1.6e-46 158.2 0.1 3.2e-46 157.2 0.1 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.12 KFP03954.1 - 4.1e-07 29.7 0.1 0.28 11.1 0.0 4.3 4 0 0 4 4 4 2 Cadherin-like Cadherin_3 PF16184.5 KFP03954.1 - 1.4e-05 25.0 6.9 1.7 8.6 0.2 5.3 5 0 0 5 5 5 2 Cadherin-like Cadherin_4 PF17803.1 KFP03954.1 - 0.029 15.0 2.7 0.029 15.0 2.7 4.2 5 0 0 5 5 5 0 Bacterial cadherin-like domain Cadherin_pro PF08758.11 KFP03954.1 - 0.11 12.7 0.0 0.36 11.0 0.0 1.9 1 0 0 1 1 1 0 Cadherin prodomain like Stevor PF17410.2 KFP03954.1 - 0.17 11.4 0.1 0.28 10.7 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame 7TM_GPCR_Srw PF10324.9 KFP03954.1 - 0.17 11.1 0.1 0.25 10.6 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw ODV-E18 PF10717.9 KFP03954.1 - 0.18 11.7 1.0 0.41 10.5 1.0 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Invasin_D3 PF09134.10 KFP03954.1 - 0.2 11.9 4.9 5.8 7.3 0.1 3.7 3 0 0 3 3 3 0 Invasin, domain 3 TNFR_c6 PF00020.18 KFP03955.1 - 1.3e-15 57.4 38.1 4.4e-07 30.2 1.0 4.5 4 0 0 4 4 4 3 TNFR/NGFR cysteine-rich region AA_permease PF00324.21 KFP03956.1 - 3.3e-52 177.7 21.4 2.9e-40 138.3 4.5 2.1 2 0 0 2 2 2 2 Amino acid permease SLC12 PF03522.15 KFP03956.1 - 4.7e-52 177.5 6.0 1.6e-18 67.0 2.2 3.2 2 1 1 3 3 3 3 Solute carrier family 12 AA_permease_2 PF13520.6 KFP03956.1 - 3.8e-16 59.0 9.4 3.8e-16 59.0 9.4 2.1 2 0 0 2 2 2 2 Amino acid permease Peptidase_M10 PF00413.24 KFP03957.1 - 1.3e-67 226.6 0.0 8.5e-67 223.9 0.0 2.2 2 1 0 2 2 2 1 Matrixin fn2 PF00040.19 KFP03957.1 - 1.4e-55 185.3 35.7 1.5e-18 66.8 7.7 3.6 3 0 0 3 3 3 3 Fibronectin type II domain Hemopexin PF00045.19 KFP03957.1 - 5.4e-20 71.1 1.5 3.5e-08 33.2 0.1 3.7 3 1 0 3 3 3 3 Hemopexin PG_binding_1 PF01471.18 KFP03957.1 - 6.4e-06 26.3 0.4 1.5e-05 25.1 0.4 1.7 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Reprolysin_4 PF13583.6 KFP03957.1 - 0.002 17.8 0.0 0.003 17.2 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 KFP03957.1 - 0.017 14.8 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 KFP03957.1 - 0.023 15.2 0.0 0.05 14.1 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFP03957.1 - 0.044 13.9 0.0 0.075 13.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF4953 PF16313.5 KFP03957.1 - 0.07 12.3 0.2 0.13 11.5 0.2 1.3 1 0 0 1 1 1 0 Met-zincin Peptidase_M66 PF10462.9 KFP03957.1 - 0.13 11.1 0.1 0.21 10.5 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Homeobox_KN PF05920.11 KFP03958.1 - 1.9e-15 56.4 0.0 2.5e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFP03958.1 - 6.7e-07 29.1 0.1 7.2e-07 29.0 0.1 1.1 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 KFP03958.1 - 0.018 14.5 0.1 0.032 13.7 0.1 1.5 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Phage_P2_GpE PF06528.12 KFP03958.1 - 0.087 12.4 0.1 0.087 12.4 0.1 1.6 2 0 0 2 2 2 0 Phage P2 GpE LBP_BPI_CETP_C PF02886.17 KFP03959.1 - 2.5e-59 200.6 0.6 4.4e-59 199.8 0.6 1.4 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 KFP03959.1 - 1.3e-31 109.4 0.2 2e-30 105.6 0.1 2.2 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain TGBp3 PF02495.17 KFP03959.1 - 0.093 12.4 0.1 16 5.3 0.0 2.4 2 0 0 2 2 2 0 Triple gene block 3 Peptidase_S10 PF00450.22 KFP03960.1 - 7e-132 440.8 0.1 8e-132 440.6 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Neuralized PF07177.12 KFP03961.1 - 3.6e-36 124.4 0.0 5.3e-36 123.9 0.0 1.3 1 1 0 1 1 1 1 Neuralized SOCS_box PF07525.16 KFP03961.1 - 2.5e-09 37.3 2.8 6e-09 36.1 2.8 1.6 1 0 0 1 1 1 1 SOCS box 4HBT_3 PF13622.6 KFP03962.1 - 4.3e-66 223.7 0.7 4.9e-66 223.5 0.7 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KFP03962.1 - 1.1e-36 125.6 0.0 6.5e-27 94.0 0.0 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase EF-hand_1 PF00036.32 KFP03964.1 - 7.7e-26 87.7 23.1 2.6e-08 32.8 0.7 5.0 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 KFP03964.1 - 1.8e-25 89.1 10.7 3.3e-12 46.7 2.7 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 KFP03964.1 - 4.7e-25 87.2 16.2 3.2e-13 49.3 0.6 3.4 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP03964.1 - 3.3e-20 70.2 13.3 5.3e-06 25.9 0.2 5.7 4 1 2 6 6 6 4 EF-hand domain EF-hand_5 PF13202.6 KFP03964.1 - 8.2e-17 59.9 19.5 0.00044 19.6 2.4 5.0 5 0 0 5 5 5 4 EF hand EF-hand_9 PF14658.6 KFP03964.1 - 4.1e-13 49.4 0.5 2.5e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KFP03964.1 - 4.7e-08 32.9 3.2 0.003 17.5 0.1 2.8 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFP03964.1 - 8.9e-05 22.8 1.0 0.059 13.7 0.4 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region p25-alpha PF05517.12 KFP03964.1 - 0.00059 20.0 0.4 0.036 14.2 0.0 2.2 1 1 1 2 2 2 1 p25-alpha TerB PF05099.13 KFP03964.1 - 0.002 18.1 4.8 0.47 10.4 0.7 2.2 2 0 0 2 2 2 2 Tellurite resistance protein TerB DUF1456 PF07308.13 KFP03964.1 - 0.0033 17.7 4.2 0.098 13.0 0.4 2.8 3 1 0 3 3 2 1 Protein of unknown function (DUF1456) EF-hand_11 PF08976.11 KFP03964.1 - 0.034 15.0 0.0 4.4 8.2 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain Phage_TAC_12 PF12363.8 KFP03964.1 - 0.056 13.9 1.6 9.4 6.7 0.1 2.2 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC UPF0154 PF03672.13 KFP03964.1 - 0.057 13.5 0.2 18 5.4 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) FlgD PF03963.14 KFP03964.1 - 0.057 13.7 0.1 4.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Flagellar hook capping protein - N-terminal region SapB_1 PF05184.15 KFP03964.1 - 0.079 13.0 0.3 3.3 7.8 0.0 2.5 2 0 0 2 2 2 0 Saposin-like type B, region 1 Syntaxin PF00804.25 KFP03964.1 - 0.094 12.4 3.4 1.1 8.8 0.5 2.2 2 0 0 2 2 2 0 Syntaxin PTS_2-RNA PF01885.16 KFP03964.1 - 0.17 11.9 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF533 PF04391.12 KFP03964.1 - 6.9 6.2 7.8 0.84 9.2 0.8 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF533) DNTTIP1_dimer PF18192.1 KFP03965.1 - 1.6e-26 92.5 0.0 2.2e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 DNTTIP1 dimerisation domain LolA PF03548.15 KFP03965.1 - 0.048 13.4 0.0 2.5 7.8 0.0 2.4 2 1 0 2 2 2 0 Outer membrane lipoprotein carrier protein LolA DUF4385 PF14328.6 KFP03965.1 - 0.11 12.6 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4385) Kunitz_BPTI PF00014.23 KFP03966.1 - 7.8e-17 61.3 13.7 1e-16 60.9 13.7 1.2 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain WAP PF00095.21 KFP03967.1 - 1.5e-12 47.7 17.2 2.6e-12 46.9 17.2 1.4 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' CTNNBL PF08216.11 KFP03968.1 - 4.2e-40 136.1 2.1 1.7e-39 134.2 2.1 2.0 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.23 KFP03968.1 - 0.0021 18.0 4.6 4.3 7.5 0.2 3.8 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 KFP03968.1 - 0.042 13.9 0.1 0.2 11.7 0.1 2.2 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain RecO_C PF02565.15 KFP03968.1 - 0.046 13.5 1.1 40 4.0 0.1 3.6 2 1 0 3 3 3 0 Recombination protein O C terminal DASH_Dad4 PF08650.10 KFP03968.1 - 0.082 12.9 0.8 11 6.1 0.1 3.7 3 0 0 3 3 3 0 DASH complex subunit Dad4 Pox_Ag35 PF03286.14 KFP03968.1 - 2 8.1 7.0 4.9 6.9 7.0 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein VHS PF00790.19 KFP03969.1 - 0.018 14.9 0.6 1.1 9.1 0.0 3.9 4 0 0 4 4 4 0 VHS domain Vac14_Fab1_bd PF12755.7 KFP03969.1 - 0.018 15.6 0.1 4.3 8.0 0.0 4.0 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region CTD_bind PF04818.13 KFP03969.1 - 0.055 14.3 0.1 17 6.3 0.0 3.6 2 0 0 2 2 2 0 RNA polymerase II-binding domain. DUF5331 PF17265.2 KFP03969.1 - 0.079 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5331) Dopey_N PF04118.14 KFP03969.1 - 0.11 11.6 2.7 1.6 7.7 0.0 3.5 2 2 1 3 3 3 0 Dopey, N-terminal DUF493 PF04359.14 KFP03969.1 - 0.15 12.6 0.0 2.9 8.6 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF493) MMS19_N PF14500.6 KFP03969.1 - 0.95 9.0 5.1 25 4.3 0.0 4.1 5 0 0 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II HEAT PF02985.22 KFP03969.1 - 5.3 7.6 21.5 33 5.1 0.0 8.4 8 0 0 8 8 8 0 HEAT repeat CREPT PF16566.5 KFP03970.1 - 1.8e-62 209.9 5.0 1.8e-62 209.9 5.0 2.1 3 0 0 3 3 3 1 Cell-cycle alteration and expression-elevated protein in tumour CTD_bind PF04818.13 KFP03970.1 - 1.9e-22 79.9 2.2 9.6e-22 77.6 0.0 3.1 4 0 0 4 4 4 1 RNA polymerase II-binding domain. Rep_4 PF05797.11 KFP03970.1 - 0.038 13.1 2.4 0.15 11.1 1.2 2.1 2 0 0 2 2 2 0 Yeast trans-acting factor (REP1/REP2) CTK3 PF12243.8 KFP03970.1 - 0.074 13.1 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 DUF2294 PF10057.9 KFP03970.1 - 0.13 12.4 1.6 0.54 10.4 0.4 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) Takusan PF04822.13 KFP03970.1 - 1.5 8.8 10.5 2.3 8.2 1.3 3.0 2 0 0 2 2 2 0 Takusan FemAB PF02388.16 KFP03970.1 - 3.9 6.3 6.9 0.21 10.5 1.2 1.7 2 0 0 2 2 2 0 FemAB family Transglut_C PF00927.22 KFP03971.1 - 2.3e-47 159.5 0.0 1.7e-23 82.8 0.0 2.8 3 0 0 3 3 3 2 Transglutaminase family, C-terminal ig like domain Transglut_N PF00868.20 KFP03971.1 - 6.3e-35 120.1 0.0 1.1e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase family Transglut_core PF01841.19 KFP03971.1 - 1.2e-17 64.4 0.7 2.4e-17 63.4 0.7 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily LBP_BPI_CETP_C PF02886.17 KFP03974.1 - 9.3e-66 221.7 0.5 1.3e-65 221.1 0.5 1.2 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 KFP03974.1 - 3.5e-33 114.5 0.0 8.4e-33 113.3 0.0 1.7 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain Radical_SAM PF04055.21 KFP03975.1 - 1.3e-30 106.9 0.0 2.5e-30 106.1 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 KFP03975.1 - 5.5e-30 103.3 0.0 1.2e-29 102.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 KFP03975.1 - 4.1e-12 45.9 0.0 7.8e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 TRAM domain LBP_BPI_CETP_C PF02886.17 KFP03976.1 - 3.5e-08 33.2 2.3 1.1e-07 31.6 1.1 2.3 2 1 0 2 2 2 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 KFP03976.1 - 1.1e-05 25.1 1.9 8.7e-05 22.2 0.2 2.7 2 1 1 3 3 3 1 LBP / BPI / CETP family, N-terminal domain TamB PF04357.13 KFP03976.1 - 0.085 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 TamB, inner membrane protein subunit of TAM complex LBP_BPI_CETP PF01273.25 KFP03977.1 - 5.2e-19 68.4 7.8 5.2e-19 68.4 7.8 2.1 2 1 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP_C PF02886.17 KFP03977.1 - 4.2e-13 49.3 2.6 1.3e-12 47.7 0.2 2.4 2 1 0 2 2 2 1 LBP / BPI / CETP family, C-terminal domain EB1 PF03271.17 KFP03978.1 - 2.9e-18 65.8 0.9 1.9e-17 63.2 0.7 2.2 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.31 KFP03978.1 - 1.9e-13 50.5 0.8 2.8e-13 50.0 0.2 1.6 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFP03978.1 - 0.008 16.0 0.1 0.023 14.5 0.0 1.8 2 1 1 3 3 3 1 CAMSAP CH domain SUIM_assoc PF16619.5 KFP03978.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 CCDC106 PF15794.5 KFP03978.1 - 0.22 11.2 0.1 0.35 10.5 0.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 ADD_DNMT3 PF17980.1 KFP03979.1 - 1e-25 89.5 0.4 2.3e-25 88.3 0.4 1.7 1 0 0 1 1 1 1 Cysteine rich ADD domain in DNMT3 DNA_methylase PF00145.17 KFP03979.1 - 3e-08 33.4 0.0 1.4e-06 27.9 0.0 2.4 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase PWWP PF00855.17 KFP03979.1 - 4.5e-07 30.2 0.0 1.2e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 PWWP domain COMM_domain PF07258.14 KFP03980.1 - 1.1e-17 63.8 0.1 2e-17 63.1 0.1 1.4 1 0 0 1 1 1 1 COMM domain Integrase_H2C2 PF17921.1 KFP03981.1 - 4.8e-05 23.4 0.0 8.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFP03981.1 - 0.053 13.7 0.4 0.11 12.7 0.4 1.6 1 1 0 1 1 1 0 H2C2 zinc finger ASXH PF13919.6 KFP03983.1 - 2.4e-36 124.8 0.1 6.3e-36 123.5 0.1 1.8 1 0 0 1 1 1 1 Asx homology domain HARE-HTH PF05066.13 KFP03983.1 - 3.6e-15 56.1 0.0 7.5e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain Kinesin PF00225.23 KFP03984.1 - 8.7e-122 406.2 0.6 8.7e-122 406.2 0.6 2.2 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KFP03984.1 - 2e-28 99.2 0.0 2e-28 99.2 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding AAA_16 PF13191.6 KFP03984.1 - 0.061 13.7 0.0 0.061 13.7 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain DUF948 PF06103.11 KFP03984.1 - 7.8 6.8 11.0 0.66 10.3 3.7 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) O-FucT PF10250.9 KFP03985.1 - 1.4e-61 209.1 0.0 1.6e-61 208.9 0.0 1.0 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase zf-C2H2_4 PF13894.6 KFP03986.1 - 4.1e-20 70.7 51.0 0.00074 20.2 1.6 6.6 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP03986.1 - 5.6e-17 61.2 58.7 5.8e-05 23.3 1.9 6.5 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP03986.1 - 5.2e-14 51.9 54.2 0.0006 20.1 6.6 7.6 7 1 0 7 7 7 5 Zinc-finger double domain zf-C2H2_6 PF13912.6 KFP03986.1 - 0.00014 21.8 0.8 0.00014 21.8 0.8 6.0 6 0 0 6 6 6 2 C2H2-type zinc finger Acyltransf_C PF16076.5 KFP03986.1 - 0.004 17.2 0.8 1.6 8.9 0.2 2.5 2 0 0 2 2 2 2 Acyltransferase C-terminus zf-Di19 PF05605.12 KFP03986.1 - 0.007 16.6 32.7 0.032 14.5 1.2 4.5 1 1 3 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KFP03986.1 - 0.029 14.7 34.6 0.26 11.6 6.2 6.0 5 1 1 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP03986.1 - 0.063 13.7 19.2 1 9.9 0.2 4.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 KFP03986.1 - 0.27 12.0 11.4 2.2 9.1 1.8 3.6 3 1 0 3 3 3 0 zinc-ribbon family zf-C2H2_11 PF16622.5 KFP03986.1 - 0.48 10.2 0.1 0.14 11.9 0.6 5.4 6 0 0 6 6 5 0 zinc-finger C2H2-type HNH_5 PF14279.6 KFP03986.1 - 1.1 9.2 13.2 1.8 8.5 0.5 4.2 3 1 0 3 3 3 0 HNH endonuclease Equine_IAV_S2 PF06502.11 KFP03986.1 - 1.7 8.8 3.9 0.5 10.5 0.3 2.0 2 0 0 2 2 1 0 Equine infectious anaemia virus S2 protein zf-C2H2_2 PF12756.7 KFP03986.1 - 3.8 7.9 34.1 6.1 7.2 0.6 5.5 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-CHCC PF10276.9 KFP03986.1 - 5.9 7.0 14.2 14 5.8 0.4 4.3 4 0 0 4 4 4 0 Zinc-finger domain FYDLN_acid PF09538.10 KFP03986.1 - 7.4 7.3 10.7 88 3.9 0.0 4.2 2 2 2 4 4 4 0 Protein of unknown function (FYDLN_acid) HypA PF01155.19 KFP03986.1 - 8 6.5 9.8 83 3.3 5.2 3.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA EMP70 PF02990.16 KFP03987.1 - 2.1e-206 686.6 13.7 3e-206 686.1 13.7 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 DUF4493 PF14900.6 KFP03987.1 - 0.11 12.4 0.1 0.17 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4493) XK-related PF09815.9 KFP03988.1 - 4.8e-87 292.2 19.2 5.4e-87 292.0 19.2 1.0 1 0 0 1 1 1 1 XK-related protein ECF_trnsprt PF12822.7 KFP03988.1 - 0.015 15.4 12.0 0.04 14.0 12.1 1.7 1 1 0 1 1 1 0 ECF transporter, substrate-specific component DSPc PF00782.20 KFP03989.1 - 4.5e-32 110.7 0.0 5.8e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFP03989.1 - 7.2e-07 29.5 0.0 1.1e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KFP03989.1 - 1.5e-06 28.0 0.0 1.9e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Pkinase PF00069.25 KFP03990.1 - 1.1e-21 77.4 0.0 1.3e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP03990.1 - 2.1e-05 23.9 0.0 2.7e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase TPX2_importin PF12214.8 KFP03991.1 - 8.7e-44 149.6 67.3 1.3e-37 129.6 11.9 7.2 4 3 2 6 6 6 3 Cell cycle regulated microtubule associated protein Aurora-A_bind PF09041.10 KFP03991.1 - 4e-25 87.7 0.8 1.1e-24 86.2 0.8 1.8 1 0 0 1 1 1 1 Aurora-A binding TPX2 PF06886.11 KFP03991.1 - 2.6e-12 46.8 18.1 2.6e-12 46.8 18.1 7.4 8 0 0 8 8 8 1 Targeting protein for Xklp2 (TPX2) LBP_BPI_CETP_C PF02886.17 KFP03992.1 - 2.8e-25 89.2 0.0 3.5e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain Peptidase_A22B PF04258.13 KFP03993.1 - 4.7e-103 344.6 9.0 5.6e-103 344.4 9.0 1.0 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 KFP03993.1 - 2.6e-05 23.9 8.2 6e-05 22.7 8.2 1.5 1 1 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease Presenilin PF01080.17 KFP03993.1 - 0.00094 18.1 4.7 0.00094 18.1 4.7 1.6 1 1 1 2 2 2 1 Presenilin DUF4345 PF14248.6 KFP03993.1 - 0.12 12.3 0.0 0.12 12.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4345) Ras PF00071.22 KFP03994.1 - 3.6e-19 68.9 0.0 4.3e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP03994.1 - 1.3e-09 38.3 0.0 1.7e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KFP03994.1 - 8e-06 25.5 0.0 1.4e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 KFP03994.1 - 9.7e-06 25.6 0.0 1.4e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP03994.1 - 4.5e-05 23.4 0.0 0.0061 16.5 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 KFP03994.1 - 0.00067 20.2 0.0 0.00073 20.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter Arf PF00025.21 KFP03994.1 - 0.002 17.6 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 KFP03994.1 - 0.003 18.0 0.1 0.0062 16.9 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KFP03994.1 - 0.0086 15.8 0.0 0.0086 15.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KFP03994.1 - 0.0094 15.4 0.0 0.42 10.0 0.0 2.3 2 1 0 2 2 2 1 Bacterial TniB protein AAA_5 PF07728.14 KFP03994.1 - 0.011 15.7 0.2 0.11 12.5 0.1 2.2 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KFP03994.1 - 0.018 15.5 0.2 0.11 12.9 0.2 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DLIC PF05783.11 KFP03994.1 - 0.023 13.5 0.0 0.049 12.5 0.0 1.6 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_22 PF13401.6 KFP03994.1 - 0.045 14.0 0.1 0.58 10.4 0.0 2.1 1 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KFP03994.1 - 0.048 13.9 0.1 0.08 13.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 KFP03994.1 - 0.094 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain RuvB_N PF05496.12 KFP03994.1 - 0.099 12.4 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain cobW PF02492.19 KFP03994.1 - 0.12 11.9 0.1 3.6 7.1 0.1 2.4 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KFP03994.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF4618 PF15397.6 KFP03995.1 - 4.7e-50 170.4 24.2 1e-28 100.5 6.4 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4618) Spc7 PF08317.11 KFP03995.1 - 0.0058 15.5 13.9 0.0058 15.5 13.9 2.1 1 1 1 2 2 2 1 Spc7 kinetochore protein DUF1664 PF07889.12 KFP03995.1 - 0.036 14.1 17.7 0.45 10.6 0.7 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) COG5 PF10392.9 KFP03995.1 - 0.13 12.5 10.1 0.25 11.5 0.6 3.0 1 1 0 2 2 2 0 Golgi transport complex subunit 5 bZIP_2 PF07716.15 KFP03995.1 - 0.17 12.0 0.5 0.17 12.0 0.5 5.0 4 2 2 6 6 6 0 Basic region leucine zipper FlaC_arch PF05377.11 KFP03995.1 - 0.19 12.2 11.6 5.9 7.4 0.6 3.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Syntaxin-6_N PF09177.11 KFP03995.1 - 0.19 12.3 13.6 37 5.0 0.4 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal SATase_N PF06426.14 KFP03995.1 - 0.21 11.9 0.2 0.21 11.9 0.2 2.2 2 1 0 2 2 2 0 Serine acetyltransferase, N-terminal CLZ PF16526.5 KFP03995.1 - 1.1 9.6 23.1 0.3 11.5 9.3 3.7 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Med9 PF07544.13 KFP03995.1 - 1.2 9.3 19.0 1.3 9.2 0.3 3.8 1 1 3 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 NPV_P10 PF05531.12 KFP03995.1 - 1.2 9.6 12.8 4.3 7.9 2.2 3.1 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF641 PF04859.12 KFP03995.1 - 1.8 8.9 19.5 0.13 12.6 8.8 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF935 PF06074.12 KFP03995.1 - 1.9 7.1 13.7 0.4 9.4 8.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF935) DUF4298 PF14131.6 KFP03995.1 - 3.5 7.7 11.8 0.36 10.8 3.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4298) PI3K_P85_iSH2 PF16454.5 KFP03995.1 - 3.6 7.2 23.8 3 7.4 17.9 2.1 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ATG16 PF08614.11 KFP03995.1 - 4.3 7.5 27.2 13 6.0 21.0 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) MbeD_MobD PF04899.12 KFP03995.1 - 7.6 6.7 13.0 4.9 7.3 7.9 2.6 2 1 0 2 2 2 0 MbeD/MobD like DUF3450 PF11932.8 KFP03995.1 - 7.7 5.7 25.7 4 6.7 5.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) LMBR1 PF04791.16 KFP03995.1 - 8 5.2 8.7 9.7 5.0 8.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein RabGAP-TBC PF00566.18 KFP03996.1 - 6.3e-26 91.4 0.0 9.2e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF1030 PF06270.11 KFP03996.1 - 0.13 12.0 0.1 0.26 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1030) Pkinase PF00069.25 KFP03997.1 - 3e-72 243.2 0.3 3.5e-72 242.9 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP03997.1 - 1.6e-20 73.5 0.0 2.1e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFP03997.1 - 4.7e-08 33.2 0.0 6.4e-06 26.3 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFP03997.1 - 0.00035 20.0 0.1 0.00058 19.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFP03997.1 - 0.0053 15.6 0.1 0.016 14.0 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KFP03997.1 - 0.0089 15.4 0.1 0.047 13.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 KFP03997.1 - 0.02 14.5 0.2 0.02 14.5 0.2 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase ABC1 PF03109.16 KFP03997.1 - 0.067 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 ABC1 family FTA2 PF13095.6 KFP03997.1 - 0.08 12.6 0.2 1.4 8.5 0.0 2.7 2 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 DUF1011 PF06237.12 KFP03998.1 - 4.6e-40 136.0 10.3 4.6e-40 136.0 10.3 3.4 4 0 0 4 4 4 1 Protein of unknown function (DUF1011) Fibrinogen_C PF00147.18 KFP03999.1 - 2.1e-66 223.9 0.5 3.3e-66 223.2 0.0 1.5 2 0 0 2 2 2 1 Fibrinogen beta and gamma chains, C-terminal globular domain ACT_6 PF13740.6 KFP03999.1 - 0.008 16.1 1.0 0.014 15.4 1.0 1.3 1 0 0 1 1 1 1 ACT domain Furin-like_2 PF15913.5 KFP04000.1 - 4.3e-48 161.9 21.3 4.3e-48 161.9 21.3 1.5 2 0 0 2 2 2 1 Furin-like repeat, cysteine-rich TSP_1 PF00090.19 KFP04000.1 - 0.00015 21.9 9.9 0.00015 21.9 9.9 3.0 2 1 0 2 2 2 1 Thrombospondin type 1 domain PI31_Prot_N PF11566.8 KFP04001.1 - 1.5e-16 60.6 0.0 1.9e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KFP04001.1 - 3.6e-09 37.7 13.9 1.2e-08 36.0 13.9 1.9 1 1 0 1 1 1 1 PI31 proteasome regulator Rad21_Rec8_N PF04825.13 KFP04002.1 - 1e-36 125.4 0.0 2.4e-36 124.2 0.0 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein PDZ_6 PF17820.1 KFP04003.1 - 2.3e-22 78.6 0.2 5e-15 55.1 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 KFP04003.1 - 2.2e-20 72.8 4.6 8.4e-12 45.3 0.1 2.7 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 KFP04003.1 - 5.6e-11 42.6 0.3 4.6e-07 30.1 0.0 2.3 1 1 0 2 2 2 2 PDZ domain Aha1_N PF09229.11 KFP04003.1 - 0.065 13.4 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 Activator of Hsp90 ATPase, N-terminal Cas_VVA1548 PF09652.10 KFP04003.1 - 0.067 13.4 0.1 3.2 8.1 0.0 2.4 2 1 0 2 2 2 0 Putative CRISPR-associated protein (Cas_VVA1548) FKBP_C PF00254.28 KFP04004.1 - 6.1e-29 100.2 0.0 6.7e-29 100.1 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase SEP PF08059.13 KFP04005.1 - 1.8e-26 92.5 0.2 4.9e-26 91.1 0.0 1.8 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 KFP04005.1 - 5.6e-19 68.1 0.1 1.1e-18 67.1 0.1 1.5 1 0 0 1 1 1 1 UBX domain V-set PF07686.17 KFP04006.1 - 1.8e-10 40.9 0.1 3.8e-10 39.9 0.1 1.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP04006.1 - 2e-10 41.1 0.1 4.4e-10 40.0 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP04006.1 - 4.4e-08 33.2 0.0 8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP04006.1 - 1.9e-06 27.9 0.0 3.1e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP04006.1 - 1.2e-05 25.5 0.1 3.7e-05 24.0 0.1 1.8 1 1 0 1 1 1 1 Immunoglobulin domain EphA2_TM PF14575.6 KFP04006.1 - 0.091 13.7 0.0 0.15 13.0 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DAG1 PF05454.11 KFP04006.1 - 0.1 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) LST1 PF05083.13 KFP04006.1 - 1.3 9.3 0.1 1.3 9.3 0.1 2.3 2 0 0 2 2 2 0 LST-1 protein Pkinase PF00069.25 KFP04007.1 - 1.3e-39 136.2 0.0 1.5e-39 136.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP04007.1 - 2.3e-23 82.8 0.1 4.5e-22 78.6 0.1 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFP04007.1 - 0.00052 19.4 0.0 0.00084 18.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP04007.1 - 0.0037 17.2 0.0 0.019 14.9 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFP04007.1 - 0.0062 15.9 0.0 0.043 13.1 0.0 2.1 1 1 0 1 1 1 1 Kinase-like PhaC_N PF07167.13 KFP04007.1 - 0.024 14.3 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus RIO1 PF01163.22 KFP04007.1 - 0.025 14.2 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KFP04007.1 - 0.029 13.2 0.0 0.035 12.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 KFP04007.1 - 0.031 13.8 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.11 KFP04007.1 - 0.092 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF5581 PF17744.1 KFP04008.1 - 8.5e-102 340.7 3.7 9.6e-102 340.5 3.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5581) fn3 PF00041.21 KFP04008.1 - 1.1e-06 28.9 0.1 2.2e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III domain AAA_12 PF13087.6 KFP04009.1 - 2.8e-73 245.8 0.8 1.3e-45 155.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 KFP04009.1 - 3.6e-72 243.3 4.9 9.3e-51 173.1 1.0 3.9 2 2 0 3 3 3 3 AAA domain RNB PF00773.19 KFP04009.1 - 5.7e-56 190.2 0.1 1.3e-55 189.1 0.1 1.6 1 0 0 1 1 1 1 RNB domain AAA_30 PF13604.6 KFP04009.1 - 7e-18 65.0 0.0 1.8e-05 24.6 0.0 3.9 3 1 0 3 3 3 3 AAA domain AAA_19 PF13245.6 KFP04009.1 - 3.9e-17 62.9 0.0 1.3e-08 35.3 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 KFP04009.1 - 9.9e-08 32.3 0.0 0.021 15.1 0.0 3.8 3 0 0 3 3 2 2 AAA domain ResIII PF04851.15 KFP04009.1 - 3.7e-06 27.1 0.0 0.016 15.2 0.0 3.2 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 KFP04009.1 - 5.3e-06 26.2 0.2 0.0015 18.3 0.0 3.3 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KFP04009.1 - 6.6e-06 26.0 3.3 0.025 14.3 0.1 4.5 3 2 2 5 5 5 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 KFP04009.1 - 2.6e-05 23.8 0.1 2.1 7.8 0.1 4.0 4 0 0 4 4 4 2 PhoH-like protein UvrD-helicase PF00580.21 KFP04009.1 - 3e-05 23.7 0.0 0.0065 16.0 0.0 3.2 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain zf-met PF12874.7 KFP04009.1 - 0.00019 21.7 3.5 0.00089 19.6 3.5 2.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF2075 PF09848.9 KFP04009.1 - 0.00024 20.5 0.0 0.0036 16.6 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 KFP04009.1 - 0.00024 21.5 0.0 0.69 10.3 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KFP04009.1 - 0.0016 18.8 0.0 2.4 8.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KFP04009.1 - 0.0054 15.8 0.1 0.48 9.4 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein zf-C2H2_jaz PF12171.8 KFP04009.1 - 0.0083 16.4 1.6 0.0083 16.4 1.6 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding OB_Dis3 PF17849.1 KFP04009.1 - 0.009 16.0 0.0 0.043 13.8 0.0 2.3 2 0 0 2 2 1 1 Dis3-like cold-shock domain 2 (CSD2) UvrD_C PF13361.6 KFP04009.1 - 0.027 13.9 0.0 11 5.3 0.0 2.8 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain AAA_7 PF12775.7 KFP04009.1 - 0.04 13.4 0.0 5.4 6.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Bac_DnaA PF00308.18 KFP04009.1 - 0.061 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_24 PF13479.6 KFP04009.1 - 0.083 12.6 0.0 2.3 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KFP04009.1 - 0.09 12.8 0.0 20 5.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KFP04009.1 - 0.12 11.7 0.0 6.5 6.1 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KFP04009.1 - 0.17 11.2 0.0 2.3 7.5 0.0 2.4 2 0 0 2 2 2 0 KaiC Helicase_RecD PF05127.14 KFP04009.1 - 0.18 11.6 0.0 1.6 8.6 0.0 2.7 2 0 0 2 2 2 0 Helicase SAND PF01342.21 KFP04010.1 - 3.1e-24 84.5 0.0 6.2e-24 83.5 0.0 1.5 1 0 0 1 1 1 1 SAND domain KfrA_N PF11740.8 KFP04010.1 - 0.72 10.6 5.0 0.28 11.8 0.4 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Stathmin PF00836.19 KFP04011.1 - 2.2e-49 166.9 15.1 2.7e-49 166.6 15.1 1.1 1 0 0 1 1 1 1 Stathmin family HrpF PF06266.12 KFP04011.1 - 0.11 12.8 0.4 0.19 12.0 0.4 1.4 1 0 0 1 1 1 0 HrpF protein UPF0242 PF06785.11 KFP04011.1 - 0.39 10.8 10.0 0.43 10.6 10.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus KNOX2 PF03791.13 KFP04011.1 - 3.8 7.1 7.8 1.1 8.9 0.1 2.8 2 1 1 3 3 3 0 KNOX2 domain Arf PF00025.21 KFP04012.1 - 1.7e-46 157.8 0.1 2.3e-46 157.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFP04012.1 - 1.6e-14 54.2 0.1 2.1e-14 53.8 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP04012.1 - 2.9e-14 53.0 0.0 3.6e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KFP04012.1 - 1e-10 41.3 0.1 2e-06 27.2 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KFP04012.1 - 1.8e-10 40.6 0.0 2.2e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFP04012.1 - 4.2e-08 33.3 0.0 5.7e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFP04012.1 - 3.6e-07 29.8 0.0 4.4e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_18 PF13238.6 KFP04012.1 - 0.047 14.2 0.0 0.071 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain G-patch PF01585.23 KFP04013.1 - 4.7e-11 42.4 0.5 4.7e-11 42.4 0.5 2.0 2 0 0 2 2 2 1 G-patch domain zf-CCCH_4 PF18044.1 KFP04013.1 - 1.1e-05 25.0 3.8 1.8e-05 24.4 3.8 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger Tudor_2 PF18104.1 KFP04013.1 - 0.004 16.8 0.0 0.0089 15.7 0.0 1.6 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain Agenet PF05641.12 KFP04013.1 - 0.0068 16.8 0.0 0.017 15.6 0.0 1.7 1 0 0 1 1 1 1 Agenet domain zf_CCCH_4 PF18345.1 KFP04013.1 - 0.016 15.3 2.5 0.028 14.5 2.5 1.4 1 0 0 1 1 1 0 Zinc finger domain G-patch_2 PF12656.7 KFP04013.1 - 0.029 14.5 0.0 0.21 11.7 0.0 2.5 2 0 0 2 2 2 0 G-patch domain zf-CCCH PF00642.24 KFP04013.1 - 0.25 11.3 2.5 0.42 10.6 2.5 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FAM176 PF14851.6 KFP04013.1 - 0.36 10.5 5.1 4.3 7.0 2.8 2.6 2 0 0 2 2 2 0 FAM176 family zf-CCCH_2 PF14608.6 KFP04013.1 - 0.45 11.1 5.2 0.72 10.4 5.2 1.3 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger NOA36 PF06524.12 KFP04013.1 - 9.2 5.5 7.7 16 4.7 7.7 1.3 1 0 0 1 1 1 0 NOA36 protein PAG PF15347.6 KFP04014.1 - 0.02 13.9 0.0 0.04 12.9 0.0 1.5 1 1 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched TPD52 PF04201.15 KFP04016.1 - 6.7e-68 227.4 5.1 4.3e-37 127.2 0.7 2.0 1 1 1 2 2 2 2 Tumour protein D52 family HIP1_clath_bdg PF16515.5 KFP04016.1 - 0.17 12.5 3.5 5.2 7.7 0.5 2.8 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DnaJ PF00226.31 KFP04017.1 - 5.1e-28 97.0 2.5 8.4e-28 96.3 2.5 1.4 1 0 0 1 1 1 1 DnaJ domain Corona_S2 PF01601.16 KFP04017.1 - 0.82 8.1 7.0 0.91 7.9 7.0 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein PRK PF00485.18 KFP04018.1 - 2.2e-59 200.5 0.0 2.5e-59 200.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CPT PF07931.12 KFP04018.1 - 3.1e-07 30.4 0.1 5e-07 29.7 0.1 1.6 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 KFP04018.1 - 0.00013 22.5 0.0 0.0002 21.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFP04018.1 - 0.0008 19.6 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KFP04018.1 - 0.00095 19.0 0.2 0.29 10.8 0.0 2.1 1 1 0 2 2 2 2 Cytidylate kinase AAA_17 PF13207.6 KFP04018.1 - 0.005 17.3 1.3 0.13 12.6 1.3 2.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFP04018.1 - 0.014 14.7 0.0 0.031 13.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin CoaE PF01121.20 KFP04018.1 - 0.018 14.8 0.0 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase CbiA PF01656.23 KFP04018.1 - 0.15 12.1 0.3 0.43 10.6 0.3 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain zf-C2H2_4 PF13894.6 KFP04019.1 - 1.4e-10 41.1 44.6 0.038 14.8 0.8 8.2 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP04019.1 - 1.5e-09 37.8 38.4 0.004 17.5 0.6 7.6 8 0 0 8 8 8 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFP04019.1 - 8e-09 35.6 20.6 0.034 14.4 0.3 5.8 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding CpXC PF14353.6 KFP04019.1 - 4.4e-07 29.9 7.7 0.042 13.9 0.0 4.4 4 0 0 4 4 4 3 CpXC protein DUF629 PF04780.12 KFP04019.1 - 9.5e-06 24.4 13.4 0.19 10.2 0.1 4.2 4 0 0 4 4 4 4 Protein of unknown function (DUF629) zf-BED PF02892.15 KFP04019.1 - 5.7e-05 23.0 31.3 0.44 10.6 0.2 6.3 4 2 2 6 6 6 3 BED zinc finger zf-C2H2_2 PF12756.7 KFP04019.1 - 0.00026 21.3 25.7 0.32 11.4 0.5 6.1 4 2 2 6 6 6 3 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFP04019.1 - 0.0011 19.2 24.7 0.85 10.1 0.3 5.9 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFP04019.1 - 0.0012 18.5 19.5 0.42 10.4 0.1 5.4 6 0 0 6 6 6 2 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KFP04019.1 - 0.0051 17.5 10.5 0.19 12.4 0.4 4.5 4 1 0 4 4 4 1 Zinc finger C2H2-type, 3 repeats zf-FCS PF06467.14 KFP04019.1 - 0.009 15.9 6.9 0.2 11.6 0.2 4.1 3 0 0 3 3 3 1 MYM-type Zinc finger with FCS sequence motif zinc_ribbon_2 PF13240.6 KFP04019.1 - 0.014 15.1 1.6 0.014 15.1 1.6 3.8 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2H2_aberr PF17017.5 KFP04019.1 - 0.12 12.5 31.1 1.7 8.7 0.3 5.4 4 1 1 5 5 5 0 Aberrant zinc-finger zf-Di19 PF05605.12 KFP04019.1 - 0.77 10.1 28.1 0.21 11.9 0.9 5.4 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_7 PF02591.15 KFP04019.1 - 0.82 9.9 9.2 9.5 6.5 0.1 4.2 5 0 0 5 5 4 0 C4-type zinc ribbon domain DUF1610 PF07754.11 KFP04019.1 - 2.4 8.2 7.4 0.11 12.4 0.6 2.4 2 0 0 2 2 1 0 Domain of unknown function (DUF1610) zinc_ribbon_9 PF14369.6 KFP04019.1 - 2.6 8.4 8.2 37 4.7 0.3 4.4 4 0 0 4 4 4 0 zinc-ribbon Zn-ribbon_8 PF09723.10 KFP04019.1 - 8.6 6.6 22.1 12 6.1 2.0 5.6 5 0 0 5 5 5 0 Zinc ribbon domain SAM_2 PF07647.17 KFP04020.1 - 3.2e-17 62.4 0.2 4.5e-17 61.9 0.2 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFP04020.1 - 4.4e-08 33.4 0.1 7.8e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFP04020.1 - 1.4e-05 24.9 0.0 2.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PilI PF10623.9 KFP04020.1 - 0.032 14.4 0.0 0.069 13.3 0.0 1.5 1 0 0 1 1 1 0 Plasmid conjugative transfer protein PilI YdaS_antitoxin PF15943.5 KFP04020.1 - 0.098 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT PRP1_N PF06424.12 KFP04021.1 - 1.3e-48 165.1 7.7 3.2e-48 163.9 7.7 1.7 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 KFP04021.1 - 8.3e-31 104.0 26.4 0.0019 18.9 0.1 13.6 6 3 9 15 15 14 8 Tetratricopeptide repeat TPR_19 PF14559.6 KFP04021.1 - 4.1e-24 84.9 10.5 9.4e-07 29.3 0.1 9.1 7 2 4 11 11 11 5 Tetratricopeptide repeat TPR_17 PF13431.6 KFP04021.1 - 4e-12 45.6 0.7 0.14 12.6 0.0 8.9 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFP04021.1 - 9.5e-10 39.0 12.8 0.00081 20.0 0.0 8.2 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFP04021.1 - 1.1e-09 37.6 12.4 0.08 13.1 0.0 10.0 11 1 1 12 12 11 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP04021.1 - 1.1e-07 31.4 0.1 0.35 11.2 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat Suf PF05843.14 KFP04021.1 - 3.3e-07 30.6 1.5 0.099 12.6 0.0 5.5 6 0 0 6 6 6 1 Suppressor of forked protein (Suf) TPR_1 PF00515.28 KFP04021.1 - 2.2e-05 24.1 0.4 0.37 10.7 0.0 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat FAT PF02259.23 KFP04021.1 - 9.1e-05 21.8 15.3 0.1 11.8 1.2 4.6 1 1 3 4 4 4 2 FAT domain TPR_9 PF13371.6 KFP04021.1 - 0.00013 22.0 2.5 19 5.5 0.0 5.7 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 KFP04021.1 - 0.0056 16.4 7.9 0.29 10.8 1.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat-like domain TPR_12 PF13424.6 KFP04021.1 - 0.012 15.8 6.7 29 5.0 0.1 6.3 5 1 0 6 6 6 0 Tetratricopeptide repeat SURF2 PF05477.11 KFP04021.1 - 0.72 9.5 6.1 49 3.5 0.0 2.4 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) RGS PF00615.19 KFP04022.1 - 5.6e-36 123.4 0.9 6.8e-36 123.1 0.9 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain 7tm_1 PF00001.21 KFP04023.1 - 4.9e-64 216.2 17.9 7.5e-64 215.6 17.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP04023.1 - 1e-13 51.3 18.9 1.6e-13 50.7 18.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 KFP04023.1 - 3.8e-08 33.0 7.4 3.8e-08 33.0 7.4 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFP04023.1 - 8.7e-08 32.2 16.2 6.5e-07 29.4 16.2 1.9 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP04023.1 - 9.2e-07 28.8 17.8 9.2e-07 28.8 17.8 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4381 PF14316.6 KFP04023.1 - 0.26 11.5 0.0 0.53 10.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) MYT1 PF08474.11 KFP04024.1 - 8.3e-78 261.7 17.4 4.5e-52 177.4 12.6 4.8 3 2 1 4 4 4 2 Myelin transcription factor 1 zf-C2HC PF01530.18 KFP04024.1 - 1e-64 214.3 69.1 1.5e-15 57.0 7.4 6.6 6 0 0 6 6 6 5 Zinc finger, C2HC type DUF1664 PF07889.12 KFP04024.1 - 0.15 12.1 3.0 0.34 11.0 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) IBR PF01485.21 KFP04024.1 - 0.52 10.6 17.4 11 6.3 0.3 5.9 4 1 1 5 5 5 0 IBR domain, a half RING-finger domain XhlA PF10779.9 KFP04024.1 - 6 7.1 8.0 22 5.3 8.0 2.0 1 1 0 1 1 1 0 Haemolysin XhlA PCMT PF01135.19 KFP04025.1 - 4.4e-26 91.9 0.0 6e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SOCS_box PF07525.16 KFP04025.1 - 4.1e-05 23.8 8.0 0.082 13.3 0.0 2.5 2 0 0 2 2 2 2 SOCS box DOT1 PF08123.13 KFP04025.1 - 0.00019 21.0 0.0 0.00032 20.3 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 KFP04025.1 - 0.0011 18.8 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 KFP04025.1 - 0.015 15.0 0.4 0.032 13.9 0.0 1.7 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_25 PF13649.6 KFP04025.1 - 0.018 15.7 0.0 0.13 12.9 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_12 PF08242.12 KFP04025.1 - 0.018 15.8 1.6 0.082 13.7 0.0 2.7 3 0 0 3 3 3 0 Methyltransferase domain REV PF00424.18 KFP04025.1 - 0.056 13.5 0.6 0.11 12.6 0.6 1.5 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) HicB_lk_antitox PF15919.5 KFP04025.1 - 0.16 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system Pkinase_Tyr PF07714.17 KFP04026.1 - 7.7e-90 300.7 0.0 9.7e-90 300.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP04026.1 - 2.3e-47 161.6 0.0 3e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFP04026.1 - 7.8e-24 83.6 0.0 1.7e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 KFP04026.1 - 7.1e-09 35.4 0.0 1.5e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP04026.1 - 8.2e-07 28.5 0.0 1.5e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Haspin_kinase PF12330.8 KFP04026.1 - 6.8e-05 22.0 0.1 0.00026 20.0 0.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KFP04026.1 - 0.00035 20.2 0.1 0.00058 19.5 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KFP04026.1 - 0.0097 15.3 0.3 0.023 14.1 0.3 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFP04026.1 - 0.028 13.8 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like SH3_2 PF07653.17 KFP04026.1 - 0.051 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain GTP_EFTU PF00009.27 KFP04027.1 - 2.4e-55 187.1 0.0 3.4e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFP04027.1 - 3.8e-40 136.7 0.0 8.2e-40 135.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KFP04027.1 - 7.9e-15 55.0 1.4 1.5e-14 54.1 0.4 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFP04027.1 - 0.00033 20.7 0.2 0.0084 16.2 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KFP04027.1 - 0.018 14.9 0.7 0.047 13.6 0.1 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Dynamin_N PF00350.23 KFP04027.1 - 0.039 14.0 0.1 10 6.1 0.0 2.4 2 0 0 2 2 2 0 Dynamin family G-alpha PF00503.20 KFP04027.1 - 0.19 10.9 0.4 0.53 9.4 0.1 1.8 2 0 0 2 2 2 0 G-protein alpha subunit KCNQ_channel PF03520.14 KFP04028.1 - 2.1e-83 278.8 0.0 3.4e-83 278.1 0.0 1.3 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel KCNQC3-Ank-G_bd PF11956.8 KFP04028.1 - 3.9e-45 152.3 0.7 3.9e-45 152.3 0.7 1.7 2 0 0 2 2 2 1 Ankyrin-G binding motif of KCNQ2-3 KCNQ2_u3 PF16642.5 KFP04028.1 - 2.4e-32 111.8 10.1 2.4e-32 111.8 10.1 2.6 3 0 0 3 3 3 1 Unstructured region on Potassium channel subunit alpha KvLQT2 Ion_trans PF00520.31 KFP04028.1 - 2e-29 102.6 5.7 2.9e-29 102.0 5.7 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFP04028.1 - 2e-13 50.1 3.1 5.2e-13 48.8 3.1 1.7 1 0 0 1 1 1 1 Ion channel Neur_chan_memb PF02932.16 KFP04029.1 - 3.4e-35 122.2 0.0 4.6e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFP04029.1 - 7.5e-35 120.3 2.5 1.2e-34 119.7 2.5 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DEP PF00610.21 KFP04030.1 - 2.6e-44 149.2 0.9 3.7e-22 78.2 0.1 2.3 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ_6 PF17820.1 KFP04030.1 - 1.7e-06 27.8 0.0 3.2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFP04030.1 - 0.094 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 PDZ domain PDZ_2 PF13180.6 KFP04030.1 - 0.1 12.9 0.0 0.44 10.9 0.0 1.9 2 0 0 2 2 2 0 PDZ domain ArfGap PF01412.18 KFP04031.1 - 1e-32 112.7 0.5 1e-32 112.7 0.5 2.5 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf zf-piccolo PF05715.13 KFP04031.1 - 0.029 14.5 1.4 0.074 13.2 1.4 1.6 1 0 0 1 1 1 0 Piccolo Zn-finger Ribosomal_L37ae PF01780.19 KFP04031.1 - 0.05 13.7 0.2 0.12 12.4 0.2 1.7 1 0 0 1 1 1 0 Ribosomal L37ae protein family NKAIN PF05640.14 KFP04032.1 - 5.7e-84 280.5 8.6 9.1e-84 279.9 8.6 1.3 1 1 0 1 1 1 1 Na,K-Atpase Interacting protein DUF1003 PF06210.11 KFP04032.1 - 0.17 12.0 3.3 0.31 11.2 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) BIR PF00653.21 KFP04033.1 - 2.5e-41 140.2 14.6 1.6e-23 83.1 0.5 3.0 3 1 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 KFP04033.1 - 1.6e-14 53.4 6.9 1.6e-14 53.4 6.9 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP04033.1 - 3.8e-07 29.9 5.9 3.8e-07 29.9 5.9 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KFP04033.1 - 0.00057 20.2 8.0 0.00057 20.2 8.0 2.7 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP04033.1 - 0.0059 16.4 8.4 0.0059 16.4 8.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF2039 PF10217.9 KFP04033.1 - 0.34 11.3 3.0 0.62 10.4 3.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) YTH PF04146.15 KFP04034.1 - 3.9e-42 144.0 0.4 1.2e-41 142.4 0.4 1.8 1 1 0 1 1 1 1 YT521-B-like domain Yae1_N PF09811.9 KFP04035.1 - 3.1e-18 65.2 55.5 1.8e+04 -20.9 55.5 5.9 1 1 0 1 1 1 0 Essential protein Yae1, N terminal MFS_1 PF07690.16 KFP04036.1 - 8.8e-45 153.1 29.0 8.8e-45 153.1 29.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Caveolin PF01146.17 KFP04036.1 - 0.11 12.4 1.7 0.4 10.6 1.7 2.0 1 1 0 1 1 1 0 Caveolin TMEM70 PF06979.12 KFP04036.1 - 5.1 7.5 6.2 0.91 9.9 0.9 2.4 2 0 0 2 2 2 0 Assembly, mitochondrial proton-transport ATP synth complex CLTH PF10607.9 KFP04037.1 - 2.6e-34 118.3 5.2 3.3e-34 117.9 5.2 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KFP04037.1 - 1.2e-12 47.3 0.5 4.7e-11 42.2 0.1 2.7 2 0 0 2 2 2 1 LisH SPOC PF07744.13 KFP04038.1 - 4.8e-29 101.2 0.0 1.5e-28 99.6 0.0 1.9 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 KFP04038.1 - 8.5e-29 100.3 4.0 9.9e-29 100.1 0.9 2.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 KFP04038.1 - 3.6e-11 42.8 8.0 9.5e-11 41.4 8.0 1.8 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.6 KFP04038.1 - 0.081 13.3 0.2 0.62 10.5 0.2 2.6 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx SlyX PF04102.12 KFP04038.1 - 0.65 10.7 9.6 0.056 14.1 2.2 3.3 2 0 0 2 2 2 0 SlyX HLH PF00010.26 KFP04039.1 - 1.5e-09 37.7 1.2 2.5e-09 37.0 0.2 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Trm5_N PF18093.1 KFP04039.1 - 0.055 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 tRNA methyltransferase 5 N-terminal domain Collagen PF01391.18 KFP04040.1 - 1e-17 63.6 57.8 1.1e-09 37.9 30.9 2.5 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) OGFr_N PF04664.13 KFP04041.1 - 4.1e-102 340.1 11.1 5.4e-102 339.7 11.1 1.1 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region Eaf7 PF07904.13 KFP04042.1 - 3e-08 34.0 3.5 1e-07 32.2 3.5 2.3 1 1 0 1 1 1 1 Chromatin modification-related protein EAF7 Asp-B-Hydro_N PF05279.11 KFP04042.1 - 0.03 14.4 4.8 0.034 14.2 4.8 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RAP1 PF07218.11 KFP04042.1 - 0.68 8.1 4.2 0.82 7.9 4.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) 7tm_1 PF00001.21 KFP04043.1 - 1.6e-13 50.6 8.8 1.9e-13 50.3 8.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) OATP PF03137.20 KFP04044.1 - 5.5e-35 120.7 1.5 5.9e-35 120.6 1.5 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family GATA PF00320.27 KFP04045.1 - 2.6e-29 100.5 16.3 1.2e-15 56.8 5.4 2.4 2 0 0 2 2 2 2 GATA zinc finger GATA-N PF05349.12 KFP04045.1 - 1.3e-17 64.7 1.3 1.3e-17 64.7 1.3 1.9 2 0 0 2 2 2 1 GATA-type transcription activator, N-terminal TF_Zn_Ribbon PF08271.12 KFP04045.1 - 3.4e-05 23.3 9.5 0.021 14.3 3.4 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.18 KFP04045.1 - 0.002 18.2 0.9 0.18 11.9 0.1 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf eIF-5_eIF-2B PF01873.17 KFP04045.1 - 0.014 15.2 5.7 2.1 8.2 2.3 2.6 2 0 0 2 2 2 0 Domain found in IF2B/IF5 DUF2387 PF09526.10 KFP04045.1 - 0.066 13.4 5.5 3.9 7.7 0.4 3.1 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) DZR PF12773.7 KFP04045.1 - 0.16 12.1 7.8 2 8.5 0.4 2.8 1 1 2 3 3 3 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 KFP04045.1 - 0.19 11.9 7.3 2.2 8.4 1.3 2.9 2 1 1 3 3 3 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 KFP04045.1 - 0.34 10.9 6.9 1.8 8.5 0.2 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Auto_anti-p27 PF06677.12 KFP04045.1 - 0.66 10.2 8.9 0.48 10.6 0.5 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Vps36-NZF-N PF16988.5 KFP04045.1 - 1.1 8.7 11.4 0.16 11.4 1.5 3.6 1 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Prim_Zn_Ribbon PF08273.12 KFP04045.1 - 3.3 8.1 13.1 0.27 11.5 2.5 3.2 3 2 0 3 3 3 0 Zinc-binding domain of primase-helicase Cytochrom_c3_2 PF14537.6 KFP04045.1 - 7.8 7.1 8.3 1.6 9.3 2.5 2.1 1 1 1 2 2 2 0 Cytochrome c3 CtIP_N PF10482.9 KFP04046.1 - 2.9e-54 182.2 19.4 2.9e-54 182.2 19.4 2.1 2 0 0 2 2 2 1 Tumour-suppressor protein CtIP N-terminal domain DivIC PF04977.15 KFP04046.1 - 0.043 13.6 0.8 0.043 13.6 0.8 3.9 5 0 0 5 5 5 0 Septum formation initiator NRBF2 PF08961.10 KFP04046.1 - 0.086 12.4 17.8 0.033 13.8 4.6 3.3 2 1 1 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator ZapB PF06005.12 KFP04046.1 - 0.51 10.8 28.5 0.077 13.4 1.3 4.1 4 0 0 4 4 4 0 Cell division protein ZapB SidE PF12252.8 KFP04046.1 - 1.1 6.6 4.8 1.6 6.2 4.8 1.1 1 0 0 1 1 1 0 Dot/Icm substrate protein HI0933_like PF03486.14 KFP04046.1 - 2.9 6.5 4.2 4.5 5.9 4.2 1.3 1 0 0 1 1 1 0 HI0933-like protein FapA PF03961.13 KFP04046.1 - 4.3 5.8 7.9 6.7 5.2 7.9 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A JIP_LZII PF16471.5 KFP04046.1 - 8.3 6.7 15.0 0.94 9.7 1.2 3.4 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II Cyclin_N PF00134.23 KFP04047.1 - 2.3e-09 37.1 0.5 4e-09 36.3 0.5 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain HGTP_anticodon PF03129.20 KFP04047.1 - 0.13 12.4 0.0 0.7 10.1 0.0 2.1 2 0 0 2 2 2 0 Anticodon binding domain Laminin_EGF PF00053.24 KFP04048.1 - 7.7e-157 509.4 440.3 2e-11 43.8 14.0 22.8 19 3 3 22 22 22 22 Laminin EGF domain Laminin_G_2 PF02210.24 KFP04048.1 - 5.7e-63 211.1 0.0 1e-19 71.4 0.0 6.1 6 0 0 6 6 6 5 Laminin G domain Laminin_I PF06008.14 KFP04048.1 - 5.6e-50 170.5 41.7 5.6e-50 170.5 41.7 2.6 2 1 0 2 2 2 1 Laminin Domain I Laminin_G_1 PF00054.23 KFP04048.1 - 7.7e-50 168.5 0.0 6e-16 58.8 0.0 5.4 5 0 0 5 5 5 5 Laminin G domain Laminin_N PF00055.17 KFP04048.1 - 1.6e-46 158.8 0.0 1.6e-46 158.8 0.0 3.3 4 0 0 4 4 4 1 Laminin N-terminal (Domain VI) Laminin_B PF00052.18 KFP04048.1 - 1.3e-37 128.7 0.8 2.5e-37 127.8 0.0 1.9 2 0 0 2 2 2 1 Laminin B (Domain IV) Laminin_II PF06009.12 KFP04048.1 - 5.6e-37 126.8 6.1 5.6e-37 126.8 6.1 5.3 3 1 3 6 6 6 1 Laminin Domain II Laminin_G_3 PF13385.6 KFP04048.1 - 1.1e-13 51.7 0.1 2.2e-05 24.6 0.0 3.5 3 0 0 3 3 3 3 Concanavalin A-like lectin/glucanases superfamily RPN13_C PF16550.5 KFP04049.1 - 3.2e-36 123.9 2.4 5.5e-36 123.1 2.4 1.4 1 0 0 1 1 1 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 KFP04049.1 - 3.6e-33 113.9 0.1 6.5e-33 113.1 0.1 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor ASXH PF13919.6 KFP04049.1 - 0.0089 16.0 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Asx homology domain GerD PF17898.1 KFP04049.1 - 0.02 14.8 1.2 0.065 13.2 0.2 2.1 2 0 0 2 2 2 0 Spore germination GerD central core domain Oxysterol_BP PF01237.18 KFP04050.1 - 1.4e-144 481.6 0.2 1.6e-144 481.4 0.2 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein 7tm_1 PF00001.21 KFP04051.1 - 2.4e-46 158.2 8.0 4.8e-46 157.2 8.0 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GTP1_OBG PF01018.22 KFP04052.1 - 2.3e-46 157.2 7.8 3e-46 156.8 7.8 1.1 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 KFP04052.1 - 1.1e-24 86.8 0.0 1.6e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFP04052.1 - 4.5e-13 49.0 0.0 1.2e-12 47.6 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.22 KFP04052.1 - 0.005 16.5 0.0 0.023 14.3 0.0 1.9 1 1 0 1 1 1 1 Ras family Arf PF00025.21 KFP04052.1 - 0.0051 16.3 0.0 0.0083 15.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Dynamin_N PF00350.23 KFP04052.1 - 0.014 15.4 0.0 0.77 9.8 0.0 2.2 1 1 1 2 2 2 0 Dynamin family Roc PF08477.13 KFP04052.1 - 0.033 14.4 0.0 0.33 11.2 0.0 2.1 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SSXT PF05030.12 KFP04053.1 - 1e-32 111.6 5.0 2.9e-32 110.1 5.0 1.8 1 0 0 1 1 1 1 SSXT protein (N-terminal region) Elf4 PF07011.11 KFP04053.1 - 0.034 14.1 1.5 1.4 8.9 0.1 2.5 1 1 1 2 2 2 0 Early Flowering 4 domain Proteasome PF00227.26 KFP04054.1 - 3.5e-64 215.8 0.2 4.4e-64 215.5 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFP04054.1 - 1.1e-14 53.7 0.4 2.7e-14 52.5 0.2 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Hormone_3 PF00159.18 KFP04054.1 - 0.15 12.2 0.5 5.7 7.1 0.1 2.3 2 0 0 2 2 2 0 Pancreatic hormone peptide FDF PF09532.10 KFP04055.1 - 2.5e-25 89.4 8.7 5.3e-25 88.3 8.7 1.5 1 0 0 1 1 1 1 FDF domain LSM14 PF12701.7 KFP04055.1 - 2.5e-12 46.7 0.0 4.1e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain TAF4 PF05236.14 KFP04056.1 - 2.3e-76 257.2 9.1 2.8e-76 256.9 9.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TAF PF02969.17 KFP04056.1 - 0.0013 18.8 0.2 0.23 11.7 0.1 2.7 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) LacI PF00356.21 KFP04056.1 - 0.062 13.1 0.2 15 5.5 0.0 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family AAA_23 PF13476.6 KFP04056.1 - 0.39 11.2 6.9 0.56 10.7 6.9 1.3 1 0 0 1 1 1 0 AAA domain Glu-tRNAGln PF02686.15 KFP04056.1 - 1.2 9.4 3.9 1.1 9.6 1.6 2.1 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit FAM217 PF15344.6 KFP04057.1 - 1.6e-85 286.9 4.3 2.1e-85 286.4 4.3 1.2 1 0 0 1 1 1 1 FAM217 family DUF4125 PF13526.6 KFP04057.1 - 0.095 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4125) CBM_21 PF03370.13 KFP04059.1 - 6.9e-32 110.0 0.1 9.3e-32 109.6 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KFP04059.1 - 5.7e-14 52.5 0.2 1.1e-13 51.6 0.2 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) CBM_25 PF03423.13 KFP04059.1 - 0.065 13.5 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) RPEL PF02755.15 KFP04060.1 - 5.8e-21 73.5 21.3 9.7e-07 28.3 3.2 4.7 4 0 0 4 4 4 4 RPEL repeat Sod_Ni PF09055.11 KFP04060.1 - 0.027 15.0 2.3 0.05 14.2 1.0 2.1 2 0 0 2 2 2 0 Nickel-containing superoxide dismutase Endothelin PF00322.17 KFP04061.1 - 0.022 14.3 4.3 0.031 13.9 4.3 1.2 1 0 0 1 1 1 0 Endothelin family zf-C2H2 PF00096.26 KFP04064.1 - 2.3e-07 30.9 10.2 0.00014 22.1 0.8 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP04064.1 - 2.4e-07 30.9 0.1 2.4e-07 30.9 0.1 3.1 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFP04064.1 - 1.1e-05 25.6 4.4 0.018 15.3 1.3 3.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KFP04064.1 - 3.2e-05 24.4 7.3 0.05 14.5 0.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-RRN7 PF11781.8 KFP04064.1 - 0.87 9.3 4.3 0.6 9.8 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 ATPase-cat_bd PF12156.8 KFP04064.1 - 0.99 10.2 6.1 0.37 11.6 1.1 2.6 2 0 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase zf-C2H2_6 PF13912.6 KFP04064.1 - 6.2 6.9 6.9 0.81 9.8 0.5 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 KFP04064.1 - 7.8 7.0 10.8 8.4 6.9 0.3 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type PRELI PF04707.14 KFP04065.1 - 2.4e-57 193.1 0.1 2.9e-57 192.9 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family ATP-synt_Eps PF04627.13 KFP04066.1 - 2.5e-13 49.8 2.3 2.7e-13 49.7 2.3 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Tubulin PF00091.25 KFP04067.1 - 6.4e-71 238.6 0.0 8.9e-71 238.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFP04067.1 - 1.3e-40 138.5 0.0 2e-40 137.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KFP04067.1 - 7.5e-05 23.0 0.0 0.00023 21.5 0.0 1.8 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KFP04067.1 - 0.0047 16.2 0.0 0.0076 15.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin like Tubulin_3 PF14881.6 KFP04067.1 - 0.0048 16.6 0.0 0.0091 15.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Peptidase_C1 PF00112.23 KFP04068.1 - 5.7e-51 173.7 13.4 7.2e-51 173.4 13.4 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Ral PF11058.8 KFP04068.1 - 0.063 12.8 0.9 0.13 11.8 0.9 1.5 1 0 0 1 1 1 0 Antirestriction protein Ral Peptidase_C1_2 PF03051.15 KFP04068.1 - 0.088 11.6 0.7 0.25 10.1 0.8 1.6 2 0 0 2 2 2 0 Peptidase C1-like family TH1 PF04858.13 KFP04069.1 - 1.2e-281 935.5 0.7 1.4e-281 935.3 0.7 1.0 1 0 0 1 1 1 1 TH1 protein G-alpha PF00503.20 KFP04070.1 - 3.9e-103 345.3 1.1 4.4e-103 345.1 1.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFP04070.1 - 1.9e-14 53.5 1.5 1.4e-13 50.7 0.5 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 KFP04070.1 - 0.0012 19.0 1.6 0.033 14.4 0.2 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KFP04070.1 - 0.021 14.3 0.0 0.34 10.4 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Peptidase_M17 PF00883.21 KFP04071.1 - 1.2e-100 336.8 0.1 1.5e-100 336.5 0.1 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 KFP04071.1 - 4.7e-17 62.4 0.3 1.7e-16 60.6 0.1 2.0 2 0 0 2 2 2 1 M17 aminopeptidase N-terminal domain 2 APCDDC PF14921.6 KFP04072.1 - 5.6e-119 395.8 0.0 2e-87 292.6 0.0 2.1 2 0 0 2 2 2 2 Adenomatosis polyposis coli down-regulated 1 Motile_Sperm PF00635.26 KFP04073.1 - 1.7e-29 101.8 0.1 3.4e-29 100.9 0.1 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ZapB PF06005.12 KFP04073.1 - 0.0071 16.8 0.6 0.012 16.0 0.6 1.3 1 0 0 1 1 1 1 Cell division protein ZapB Com_YlbF PF06133.11 KFP04073.1 - 0.031 14.9 0.5 0.055 14.1 0.5 1.3 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA LcrG PF07216.12 KFP04073.1 - 0.048 13.6 0.3 0.083 12.8 0.3 1.3 1 0 0 1 1 1 0 LcrG protein IF2_N PF04760.15 KFP04073.1 - 0.064 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region CHD5 PF04420.14 KFP04073.1 - 0.17 11.7 1.4 0.45 10.4 0.9 1.7 2 0 0 2 2 2 0 CHD5-like protein Ras PF00071.22 KFP04074.1 - 6.8e-56 188.3 0.0 7.8e-56 188.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP04074.1 - 2.5e-36 124.5 0.0 3.9e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP04074.1 - 1.9e-14 53.5 0.0 2e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP04074.1 - 3.6e-05 23.8 0.0 7.1e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFP04074.1 - 7.4e-05 22.2 0.0 9.7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFP04074.1 - 0.00012 21.7 0.0 0.00052 19.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFP04074.1 - 0.00037 20.4 0.6 0.13 12.2 0.0 2.4 1 1 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 KFP04074.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KFP04074.1 - 0.013 15.9 0.0 0.026 14.9 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KFP04074.1 - 0.049 13.4 0.0 0.1 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain DIT1_PvcA PF05141.12 KFP04074.1 - 0.076 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein CNTF PF01110.17 KFP04074.1 - 0.076 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Ciliary neurotrophic factor AAA_5 PF07728.14 KFP04074.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) HEAT PF02985.22 KFP04075.1 - 4e-24 82.6 15.5 0.0086 16.3 0.0 9.6 9 0 0 9 9 9 7 HEAT repeat HEAT_2 PF13646.6 KFP04075.1 - 3.7e-10 40.0 0.9 0.19 12.1 0.0 7.0 5 3 3 8 8 8 4 HEAT repeats WRNPLPNID PF15017.6 KFP04075.1 - 2.4e-07 31.5 0.1 2.4e-07 31.5 0.1 3.3 3 0 0 3 3 3 1 Putative WW-binding domain and destruction box Vac14_Fab1_bd PF12755.7 KFP04075.1 - 0.00085 19.9 2.0 1.8 9.2 0.1 5.1 4 3 1 5 5 5 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KFP04075.1 - 0.0051 16.9 8.2 9.5 6.2 0.0 6.0 5 2 3 8 8 8 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KFP04075.1 - 0.067 13.7 1.8 2.6 8.7 0.2 4.1 4 0 0 4 4 4 0 HEAT-like repeat Ins134_P3_kin PF05770.11 KFP04075.1 - 0.18 11.3 1.3 0.72 9.3 0.1 2.4 2 0 0 2 2 2 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ank_2 PF12796.7 KFP04076.1 - 9.7e-20 71.0 1.5 6.9e-10 39.4 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP04076.1 - 1.5e-11 44.5 0.5 1.7e-10 41.2 0.6 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP04076.1 - 3.6e-10 39.9 1.5 2.1e-05 24.7 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFP04076.1 - 5.8e-09 36.0 0.6 0.0023 18.3 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFP04076.1 - 3.1e-08 33.2 1.9 0.00068 19.9 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ubiquitin_2 PF14560.6 KFP04076.1 - 3.7e-05 24.1 0.0 6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 KFP04076.1 - 0.014 15.2 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family DIX PF00778.17 KFP04076.1 - 0.14 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 DIX domain Rad60-SLD PF11976.8 KFP04076.1 - 0.21 11.4 0.1 0.34 10.8 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like LLC1 PF14945.6 KFP04077.1 - 4.4e-39 133.7 1.0 5.3e-39 133.5 1.0 1.0 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Spc7_N PF15402.6 KFP04077.1 - 0.24 9.6 0.7 0.28 9.4 0.7 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 SP_C-Propep PF08999.10 KFP04078.1 - 0.7 9.7 3.7 2 8.3 3.7 1.7 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide PEPCK_GTP PF00821.18 KFP04079.1 - 2e-168 559.8 0.4 2.4e-168 559.5 0.4 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 KFP04079.1 - 3.5e-98 327.5 0.0 4.7e-98 327.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain TPK_catalytic PF04263.16 KFP04079.1 - 0.078 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain zf-H2C2_2 PF13465.6 KFP04080.1 - 3.8e-36 121.9 67.6 2.5e-08 34.0 1.6 8.2 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFP04080.1 - 9.9e-20 69.8 74.6 2.4e-05 24.5 0.6 8.9 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP04080.1 - 2.3e-18 65.3 69.0 0.0012 19.5 0.7 9.1 9 0 0 9 9 9 7 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFP04080.1 - 3.9e-12 45.7 68.9 1.8e-05 24.4 2.1 9.6 9 1 0 9 9 9 6 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFP04080.1 - 1.7e-08 34.5 38.8 0.06 13.6 2.6 7.5 7 0 0 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP04080.1 - 0.011 15.7 2.4 0.011 15.7 2.4 9.8 12 0 0 12 12 12 0 C2H2-type zinc finger zinc_ribbon_15 PF17032.5 KFP04080.1 - 0.032 15.0 30.4 0.44 11.3 1.4 4.1 3 1 1 4 4 4 0 zinc-ribbon family GAGA PF09237.11 KFP04080.1 - 0.035 13.9 9.0 7.1 6.5 0.0 4.7 1 1 4 5 5 5 0 GAGA factor zf-met PF12874.7 KFP04080.1 - 0.047 14.1 36.9 0.096 13.1 0.5 6.9 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFP04080.1 - 0.13 12.0 0.1 0.13 12.0 0.1 6.8 9 0 0 9 9 9 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KFP04080.1 - 0.59 10.5 42.7 1.5 9.2 13.3 5.6 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) BolA PF01722.18 KFP04080.1 - 2.1 8.7 8.2 23 5.3 0.1 3.6 1 1 2 3 3 3 0 BolA-like protein RNA_POL_M_15KD PF02150.16 KFP04080.1 - 3.8 7.5 25.5 4.8 7.1 0.2 6.3 7 0 0 7 7 7 0 RNA polymerases M/15 Kd subunit WD40 PF00400.32 KFP04082.1 - 9e-11 42.2 17.3 0.02 15.8 0.2 5.9 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP04082.1 - 0.0007 19.9 0.0 0.97 9.8 0.2 3.6 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP04082.1 - 0.0096 14.6 0.4 0.92 8.1 0.1 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 TP6A_N PF04406.14 KFP04084.1 - 6.3e-25 86.9 0.5 1.2e-24 86.1 0.5 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF760 PF05542.11 KFP04084.1 - 0.028 14.8 0.1 1.3 9.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF760) TGFb_propeptide PF00688.18 KFP04085.1 - 6e-68 229.2 0.0 8.4e-68 228.8 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 KFP04085.1 - 2.1e-37 128.2 0.9 6e-37 126.8 0.7 1.9 2 0 0 2 2 2 1 Transforming growth factor beta like domain TF_AP-2 PF03299.14 KFP04086.1 - 1.3e-87 292.9 0.0 1.8e-87 292.4 0.0 1.2 1 0 0 1 1 1 1 Transcription factor AP-2 4PPT_N PF17837.1 KFP04086.1 - 0.1 12.7 0.0 0.48 10.6 0.0 2.1 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain Rtf2 PF04641.12 KFP04087.1 - 9.5e-84 280.8 9.5 1.2e-83 280.5 9.5 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 KFP04087.1 - 0.03 14.5 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein DUF1180 PF06679.12 KFP04087.1 - 0.8 10.1 3.0 1.3 9.4 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) MAS20 PF02064.15 KFP04087.1 - 1.4 9.0 3.8 1.3 9.1 2.5 1.6 1 1 0 1 1 1 0 MAS20 protein import receptor Branch PF02485.21 KFP04088.1 - 6.9e-52 176.4 1.0 1.1e-51 175.7 0.2 1.6 2 0 0 2 2 2 1 Core-2/I-Branching enzyme WD40 PF00400.32 KFP04089.1 - 3.6e-33 113.1 1.8 2.1e-06 28.3 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat CSTF1_dimer PF16699.5 KFP04089.1 - 8.7e-23 79.8 0.3 1.5e-22 79.1 0.3 1.4 1 0 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain ANAPC4_WD40 PF12894.7 KFP04089.1 - 2.9e-12 46.7 0.0 0.017 15.4 0.0 4.7 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KFP04089.1 - 6.5e-06 24.7 0.1 0.00012 20.6 0.0 2.2 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KFP04089.1 - 0.0017 17.4 1.0 0.6 9.0 0.2 2.9 1 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Pkinase PF00069.25 KFP04090.1 - 1.1e-63 215.1 0.0 1.9e-63 214.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP04090.1 - 6.4e-38 130.5 0.1 1.1e-37 129.7 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP04090.1 - 0.00049 19.5 0.0 0.0038 16.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFP04090.1 - 0.0056 15.5 1.8 0.011 14.5 1.8 1.4 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP04090.1 - 0.028 14.3 0.0 0.059 13.3 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KFP04090.1 - 0.034 13.8 0.7 1.4 8.4 0.0 2.5 1 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 KFP04090.1 - 0.048 13.2 0.0 0.048 13.2 0.0 2.2 1 1 0 2 2 2 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.11 KFP04090.1 - 0.065 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RNA_pol_Rpc4 PF05132.14 KFP04090.1 - 0.15 12.5 7.5 0.25 11.8 7.5 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Connexin PF00029.19 KFP04090.1 - 0.15 11.8 2.0 0.23 11.2 2.0 1.2 1 0 0 1 1 1 0 Connexin DUF3408 PF11888.8 KFP04090.1 - 0.32 11.1 8.8 0.72 10.0 8.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Zip PF02535.22 KFP04090.1 - 0.47 9.6 0.8 0.62 9.2 0.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 KFP04090.1 - 0.51 9.0 6.8 0.64 8.7 6.8 1.1 1 0 0 1 1 1 0 Presenilin CCSAP PF15748.5 KFP04090.1 - 0.61 10.2 13.7 0.99 9.5 13.7 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated RR_TM4-6 PF06459.12 KFP04090.1 - 1 9.1 10.6 1.5 8.6 10.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1279 PF06916.13 KFP04091.1 - 2.9e-28 98.2 0.9 3.4e-28 98.0 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) 7tm_1 PF00001.21 KFP04092.1 - 3.6e-37 128.1 37.8 1.1e-35 123.3 37.8 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP04092.1 - 4.3e-08 33.2 29.7 1.7e-07 31.2 25.1 2.7 1 1 1 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KFP04092.1 - 2.3e-06 27.2 38.0 4.8e-06 26.1 38.0 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP04092.1 - 0.00043 20.0 28.0 0.00043 20.0 28.0 2.8 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx C1q PF00386.21 KFP04093.1 - 4.9e-19 68.8 0.4 5.4e-19 68.7 0.4 1.0 1 0 0 1 1 1 1 C1q domain PH_2 PF08458.10 KFP04093.1 - 0.029 14.7 0.0 7.6 6.9 0.0 2.1 1 1 1 2 2 2 0 Plant pleckstrin homology-like region Prefoldin_2 PF01920.20 KFP04094.1 - 3.5e-26 91.2 10.3 4.1e-26 91.0 10.3 1.0 1 0 0 1 1 1 1 Prefoldin subunit NPV_P10 PF05531.12 KFP04094.1 - 0.00016 22.1 6.6 0.0083 16.6 1.1 2.1 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein DUF5082 PF16888.5 KFP04094.1 - 0.00037 20.8 10.6 0.0014 18.9 10.6 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF5082) Prefoldin PF02996.17 KFP04094.1 - 0.0013 18.6 8.6 0.13 12.2 8.6 2.2 1 1 0 1 1 1 1 Prefoldin subunit KxDL PF10241.9 KFP04094.1 - 0.002 18.4 5.9 0.016 15.5 0.8 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein DUF5320 PF17253.2 KFP04094.1 - 0.0036 18.4 4.2 0.013 16.5 0.4 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF5320) DivIVA PF05103.13 KFP04094.1 - 0.004 17.2 5.4 0.0054 16.8 5.4 1.2 1 0 0 1 1 1 1 DivIVA protein DUF4854 PF16146.5 KFP04094.1 - 0.007 16.7 1.6 0.0098 16.2 1.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4854) TPR_MLP1_2 PF07926.12 KFP04094.1 - 0.0075 16.3 10.5 0.17 12.0 4.4 2.1 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein FliD_C PF07195.12 KFP04094.1 - 0.0089 15.5 3.2 0.019 14.4 0.1 2.0 2 0 0 2 2 2 1 Flagellar hook-associated protein 2 C-terminus Helo_like_N PF17111.5 KFP04094.1 - 0.009 15.4 6.0 0.33 10.3 0.8 2.0 1 1 1 2 2 2 2 Fungal N-terminal domain of STAND proteins Med30 PF11315.8 KFP04094.1 - 0.0094 16.2 5.5 0.012 15.8 5.5 1.1 1 0 0 1 1 1 1 Mediator complex subunit 30 Sec2p PF06428.11 KFP04094.1 - 0.01 15.8 7.5 0.11 12.5 1.0 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Cep57_CLD_2 PF14197.6 KFP04094.1 - 0.01 15.9 7.9 0.72 10.0 1.0 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF4618 PF15397.6 KFP04094.1 - 0.015 14.8 6.9 0.064 12.7 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Spc24 PF08286.11 KFP04094.1 - 0.015 15.5 7.4 0.34 11.2 1.7 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Fib_alpha PF08702.10 KFP04094.1 - 0.019 15.1 6.1 0.72 10.0 0.5 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.22 KFP04094.1 - 0.02 15.1 6.7 1.4 9.2 0.5 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4140 PF13600.6 KFP04094.1 - 0.025 15.0 5.0 0.82 10.1 0.3 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 KFP04094.1 - 0.027 14.2 5.9 0.8 9.5 0.5 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF1664 PF07889.12 KFP04094.1 - 0.031 14.3 5.6 0.067 13.2 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FAM76 PF16046.5 KFP04094.1 - 0.032 13.6 5.3 0.042 13.2 5.3 1.2 1 0 0 1 1 1 0 FAM76 protein DUF2721 PF11026.8 KFP04094.1 - 0.037 13.9 0.8 3.2 7.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) ABC_tran_CTD PF16326.5 KFP04094.1 - 0.037 14.3 9.7 0.73 10.1 3.6 2.5 2 1 0 2 2 2 0 ABC transporter C-terminal domain Rx_N PF18052.1 KFP04094.1 - 0.041 14.2 6.5 0.065 13.5 0.8 2.2 2 0 0 2 2 2 0 Rx N-terminal domain FlaC_arch PF05377.11 KFP04094.1 - 0.041 14.3 9.2 1.4 9.4 1.2 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Atg14 PF10186.9 KFP04094.1 - 0.045 12.8 1.9 0.092 11.8 1.9 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RNA_pol_L_2 PF13656.6 KFP04094.1 - 0.052 13.3 0.5 4.4 7.2 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Fzo_mitofusin PF04799.13 KFP04094.1 - 0.054 13.0 4.1 0.6 9.7 0.5 2.1 2 0 0 2 2 2 0 fzo-like conserved region APG6_N PF17675.1 KFP04094.1 - 0.058 13.9 10.3 0.72 10.4 3.5 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region HIP1_clath_bdg PF16515.5 KFP04094.1 - 0.061 13.9 7.5 1.4 9.6 0.8 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 YabA PF06156.13 KFP04094.1 - 0.064 13.9 7.0 0.12 13.0 0.6 2.3 1 1 1 2 2 2 0 Initiation control protein YabA BLI1 PF17324.2 KFP04094.1 - 0.068 13.8 6.6 0.64 10.7 1.2 2.2 2 0 0 2 2 2 0 BLOC-1 interactor 1 GARP PF16731.5 KFP04094.1 - 0.078 12.7 2.6 1.8 8.2 0.3 2.1 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma CdvA PF18822.1 KFP04094.1 - 0.083 12.7 9.8 0.059 13.2 2.5 2.1 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Mod_r PF07200.13 KFP04094.1 - 0.087 12.9 9.5 0.45 10.6 9.5 1.9 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein UPF0242 PF06785.11 KFP04094.1 - 0.095 12.8 11.8 0.15 12.2 11.8 1.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GvpL_GvpF PF06386.11 KFP04094.1 - 0.095 12.6 2.5 0.29 11.0 0.2 1.9 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF LXG PF04740.12 KFP04094.1 - 0.15 11.8 8.3 2.1 8.0 0.6 2.2 2 0 0 2 2 2 0 LXG domain of WXG superfamily Med9 PF07544.13 KFP04094.1 - 0.16 12.1 12.9 0.54 10.4 3.2 3.2 2 2 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DASH_Dam1 PF08653.10 KFP04094.1 - 0.19 11.5 2.5 2.2 8.1 0.2 2.6 2 1 1 3 3 3 0 DASH complex subunit Dam1 DUF4709 PF15821.5 KFP04094.1 - 0.2 11.9 5.5 0.38 11.0 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) DASH_Spc34 PF08657.10 KFP04094.1 - 0.21 11.4 8.1 0.66 9.7 7.1 1.9 1 1 1 2 2 2 0 DASH complex subunit Spc34 FlxA PF14282.6 KFP04094.1 - 0.22 11.5 12.2 0.46 10.5 0.9 2.2 1 1 1 2 2 2 0 FlxA-like protein V_ATPase_I PF01496.19 KFP04094.1 - 0.24 9.3 4.4 0.28 9.0 4.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CCDC-167 PF15188.6 KFP04094.1 - 0.25 11.7 8.5 0.55 10.6 3.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 TMF_DNA_bd PF12329.8 KFP04094.1 - 0.27 11.3 13.0 1.8 8.6 1.3 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding UPF0449 PF15136.6 KFP04094.1 - 0.29 11.6 7.0 1.1 9.7 1.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 GrpE PF01025.19 KFP04094.1 - 0.31 10.7 7.9 1.3 8.6 1.4 2.1 2 0 0 2 2 2 0 GrpE ERM PF00769.19 KFP04094.1 - 0.32 10.8 10.1 0.34 10.7 3.7 2.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family FmiP_Thoc5 PF09766.9 KFP04094.1 - 0.39 10.0 8.6 0.83 8.9 1.5 2.0 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 Csm1_N PF18504.1 KFP04094.1 - 0.43 11.0 9.7 3.4 8.1 1.6 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain TBCA PF02970.16 KFP04094.1 - 0.56 10.6 9.6 1.2 9.5 8.4 2.0 1 1 1 2 2 2 0 Tubulin binding cofactor A DUF2508 PF10704.9 KFP04094.1 - 0.61 10.3 6.6 2.6 8.3 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) DUF2203 PF09969.9 KFP04094.1 - 0.65 10.7 4.7 2 9.1 4.7 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) CHD5 PF04420.14 KFP04094.1 - 0.66 9.8 2.6 2.3 8.1 0.2 2.0 2 0 0 2 2 2 0 CHD5-like protein Syntaxin-6_N PF09177.11 KFP04094.1 - 0.72 10.4 7.9 22 5.7 7.9 2.1 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Fmp27_WPPW PF10359.9 KFP04094.1 - 0.97 8.2 9.4 0.35 9.7 2.1 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain KfrA_N PF11740.8 KFP04094.1 - 0.98 10.1 5.7 1.8 9.3 5.1 1.7 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term HalX PF08663.10 KFP04094.1 - 1.2 9.6 7.3 8.4 6.8 1.6 2.3 2 0 0 2 2 2 0 HalX domain PspB PF06667.12 KFP04094.1 - 1.2 9.2 3.7 2.1 8.5 0.6 2.4 2 1 0 2 2 2 0 Phage shock protein B Med4 PF10018.9 KFP04094.1 - 1.3 8.6 9.4 1.8 8.2 1.3 2.1 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 bZIP_1 PF00170.21 KFP04094.1 - 1.3 9.1 10.4 2.4 8.3 3.5 2.3 2 0 0 2 2 2 0 bZIP transcription factor DUF4407 PF14362.6 KFP04094.1 - 1.4 8.2 5.7 4.6 6.5 5.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MetOD2 PF18548.1 KFP04094.1 - 1.4 9.1 7.4 4.1 7.6 1.7 2.2 2 0 0 2 2 2 0 Metanogen output domain 2 SlyX PF04102.12 KFP04094.1 - 1.6 9.4 8.2 2.8 8.6 1.3 2.4 2 1 0 2 2 2 0 SlyX Mt_ATP-synt_D PF05873.12 KFP04094.1 - 3.4 7.5 8.3 1.3 8.8 1.0 2.1 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) PCRF PF03462.18 KFP04094.1 - 4.3 7.2 10.5 28 4.5 10.5 1.9 1 1 0 1 1 1 0 PCRF domain AAA_23 PF13476.6 KFP04094.1 - 4.6 7.7 12.8 6.3 7.2 12.8 1.3 1 1 0 1 1 1 0 AAA domain Med7 PF05983.11 KFP04094.1 - 9.1 6.3 8.8 11 6.0 2.5 2.2 2 0 0 2 2 2 0 MED7 protein TMPIT PF07851.13 KFP04094.1 - 9.1 5.4 7.7 42 3.2 7.7 1.8 1 1 0 1 1 1 0 TMPIT-like protein p450 PF00067.22 KFP04095.1 - 8.5e-89 298.4 0.2 9.7e-89 298.2 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Actin PF00022.19 KFP04095.1 - 0.15 10.6 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Actin zf-C2H2 PF00096.26 KFP04096.1 - 5.2e-20 70.7 50.3 0.00017 21.9 1.0 8.9 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP04096.1 - 3.7e-18 64.7 53.6 0.001 19.7 0.9 9.0 8 0 0 8 8 8 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP04096.1 - 2.3e-08 34.1 68.8 1.1e-07 32.0 0.4 12.0 14 0 0 14 14 12 5 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFP04096.1 - 4.6e-05 23.1 3.1 4.6e-05 23.1 3.1 8.7 9 1 0 9 9 9 3 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KFP04096.1 - 0.00034 20.9 33.7 0.00049 20.4 1.9 6.8 4 2 1 6 6 6 1 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 KFP04096.1 - 0.00037 21.2 1.2 0.00037 21.2 1.2 5.8 5 2 2 7 7 6 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 KFP04096.1 - 0.014 15.4 1.0 0.014 15.4 1.0 7.9 7 2 0 7 7 7 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFP04096.1 - 0.17 11.8 15.0 0.65 10.0 0.8 5.8 5 0 0 5 5 5 0 zinc-finger of a C2HC-type CpXC PF14353.6 KFP04096.1 - 0.17 11.9 16.3 4 7.5 0.1 5.7 4 1 0 4 4 4 0 CpXC protein zf_C2H2_ZHX PF18387.1 KFP04096.1 - 0.32 10.7 14.4 4 7.2 0.0 5.3 5 0 0 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 KFP04096.1 - 0.63 10.4 28.1 0.8 10.1 0.9 6.5 6 0 0 6 6 5 0 Zinc-finger double-stranded RNA-binding C1_1 PF00130.22 KFP04096.1 - 2.4 8.1 19.8 1.5 8.8 0.8 5.1 4 1 1 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2256 PF10013.9 KFP04096.1 - 3.6 7.8 10.8 43 4.3 0.0 5.2 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) GAGA PF09237.11 KFP04096.1 - 4 7.3 6.6 1.7 8.5 0.1 3.0 3 0 0 3 3 3 0 GAGA factor zf-C2H2_4 PF13894.6 KFP04098.1 - 5.9e-10 39.1 28.5 0.049 14.5 0.1 6.1 6 0 0 6 6 5 4 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFP04098.1 - 1.9e-09 37.7 27.0 0.005 17.1 0.3 4.7 3 1 1 4 4 4 4 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 KFP04098.1 - 0.00038 21.1 20.8 0.18 12.5 0.8 5.1 4 1 1 5 5 5 3 Zinc finger C2H2-type, 3 repeats zf-C2H2 PF00096.26 KFP04098.1 - 0.00052 20.3 34.4 0.4 11.2 0.1 6.1 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-met PF12874.7 KFP04098.1 - 0.0052 17.1 11.6 0.34 11.4 0.3 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP04098.1 - 0.008 16.4 15.0 0.02 15.2 0.2 3.9 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding Zn_Tnp_IS1 PF03811.13 KFP04098.1 - 0.52 10.1 3.5 8.9 6.1 0.9 2.9 2 0 0 2 2 2 0 InsA N-terminal domain zf-C2H2_12 PF18658.1 KFP04098.1 - 0.92 9.1 8.1 5.4 6.7 0.0 3.7 3 0 0 3 3 3 0 Zinc-finger C2H2-type PhnA_Zn_Ribbon PF08274.12 KFP04098.1 - 1.2 9.1 3.7 3.6 7.6 0.0 2.9 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-CpG_bind_C PF12269.8 KFP04098.1 - 1.9 8.2 13.8 0.11 12.3 2.1 3.2 3 0 0 3 3 3 0 CpG binding protein zinc finger C terminal domain zf-H2C2_2 PF13465.6 KFP04098.1 - 3.5 8.2 18.8 7.1 7.2 0.3 5.8 5 0 0 5 5 5 0 Zinc-finger double domain PhoLip_ATPase_C PF16212.5 KFP04099.1 - 1.8e-51 175.3 24.4 1.8e-51 175.3 24.4 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFP04099.1 - 3.8e-16 58.5 3.5 1e-15 57.2 3.5 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFP04099.1 - 3e-14 53.8 2.7 3.5e-11 43.8 2.7 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFP04099.1 - 3e-10 39.9 0.0 3e-10 39.9 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KFP04099.1 - 2.2e-08 34.1 0.0 2.9e-07 30.5 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFP04099.1 - 0.0069 16.2 0.0 0.03 14.1 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase GNVR PF13807.6 KFP04099.1 - 0.042 13.8 0.1 0.16 11.9 0.1 2.0 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase DUF4174 PF13778.6 KFP04099.1 - 0.19 12.2 0.1 0.49 10.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) RHD_dimer PF16179.5 KFP04100.1 - 7.3e-25 87.0 0.3 1.6e-24 85.8 0.3 1.6 1 0 0 1 1 1 1 Rel homology dimerisation domain RHD_DNA_bind PF00554.22 KFP04100.1 - 1.9e-22 80.0 0.5 5.8e-22 78.4 0.5 1.8 1 1 0 1 1 1 1 Rel homology DNA-binding domain TIG PF01833.24 KFP04100.1 - 3.3e-06 27.1 0.2 1.9e-05 24.7 0.0 2.5 2 0 0 2 2 2 1 IPT/TIG domain Ion_trans PF00520.31 KFP04101.1 - 1.7e-37 129.0 9.2 2.5e-37 128.4 9.2 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFP04101.1 - 1.5e-26 92.5 0.0 3.5e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFP04101.1 - 4.4e-14 52.2 3.0 4.4e-14 52.2 3.0 2.1 2 0 0 2 2 2 1 Ion channel ThiF PF00899.21 KFP04102.1 - 4.5e-35 121.2 0.0 6.7e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KFP04102.1 - 1.3e-10 41.8 0.0 2.7e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Glycos_transf_2 PF00535.26 KFP04103.1 - 3.4e-33 114.9 0.0 4e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KFP04103.1 - 1.3e-09 38.3 0.0 2.7e-09 37.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KFP04103.1 - 4.4e-05 23.0 0.0 8.4e-05 22.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 KFP04103.1 - 0.001 18.6 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KFP04103.1 - 0.13 12.8 0.0 0.27 11.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Homeodomain PF00046.29 KFP04104.1 - 2e-07 30.8 0.5 5.2e-07 29.4 0.5 1.7 1 0 0 1 1 1 1 Homeodomain zf-C2H2_4 PF13894.6 KFP04104.1 - 0.00074 20.2 53.1 0.011 16.5 0.3 9.3 9 0 0 9 9 9 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KFP04104.1 - 0.019 15.7 10.9 2.3 8.9 0.6 5.0 4 0 0 4 4 4 0 Zinc finger C2H2-type, 3 repeats Homeobox_KN PF05920.11 KFP04104.1 - 0.074 13.0 0.3 0.28 11.1 0.3 2.0 1 0 0 1 1 1 0 Homeobox KN domain zf-Di19 PF05605.12 KFP04104.1 - 0.1 12.9 0.2 0.1 12.9 0.2 7.4 7 2 1 8 8 8 0 Drought induced 19 protein (Di19), zinc-binding Thioredoxin_3 PF13192.6 KFP04104.1 - 0.26 11.4 3.5 8.5 6.5 0.0 4.7 5 0 0 5 5 5 0 Thioredoxin domain zf-C2H2_9 PF16293.5 KFP04104.1 - 3.3 7.6 12.1 0.13 12.1 0.2 4.3 5 0 0 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 KFP04104.1 - 6.5 7.2 32.8 0.033 14.5 4.2 6.9 4 4 3 7 7 7 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 KFP04104.1 - 8.2 6.2 21.6 1.4 8.7 0.0 5.3 5 1 1 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain PB1 PF00564.24 KFP04105.1 - 7.2e-13 48.3 0.0 1.2e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 PB1 domain PDZ PF00595.24 KFP04105.1 - 4.8e-11 42.8 0.0 9.1e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP04105.1 - 2.7e-08 33.5 0.1 5.3e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 PDZ domain CENP-F_leu_zip PF10473.9 KFP04106.1 - 6.6e-05 23.0 29.6 6.6e-05 23.0 29.6 7.7 1 1 7 8 8 8 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KFP04106.1 - 0.00071 19.9 25.6 0.00071 19.9 25.6 8.1 1 1 6 7 7 7 1 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 KFP04106.1 - 0.0009 19.2 19.8 0.0009 19.2 19.8 12.1 3 3 10 13 13 13 4 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 KFP04106.1 - 0.0023 18.0 6.8 0.0023 18.0 6.8 8.6 1 1 5 8 8 8 2 Protein of unknown function (DUF1664) Y_phosphatase PF00102.27 KFP04107.1 - 1.5e-80 270.2 0.0 2e-80 269.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFP04107.1 - 8.1e-05 22.4 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP04107.1 - 0.0033 17.4 0.0 0.006 16.6 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFP04107.1 - 0.048 13.8 0.1 0.21 11.7 0.1 2.2 1 1 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.12 KFP04107.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Serinc PF03348.15 KFP04108.1 - 9.7e-175 581.6 16.5 1.1e-174 581.4 16.5 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) CRAL_TRIO PF00650.20 KFP04109.1 - 3.6e-33 114.5 0.0 5.2e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFP04109.1 - 2.2e-07 30.9 0.2 6.1e-07 29.5 0.2 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFP04109.1 - 4.5e-05 23.6 0.0 7.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Hormone_recep PF00104.30 KFP04110.1 - 1.7e-40 138.8 0.0 3.2e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFP04110.1 - 3.4e-30 104.3 18.4 5.5e-30 103.6 18.4 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) CAP PF00188.26 KFP04111.1 - 2.8e-25 89.6 3.8 3.7e-25 89.2 3.8 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Myticin-prepro PF10690.9 KFP04111.1 - 0.98 9.7 4.9 1.9 8.8 4.9 1.4 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel Scs3p PF10261.9 KFP04112.1 - 3e-25 89.2 16.0 2.3e-17 63.3 3.8 2.4 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.21 KFP04112.1 - 0.00015 21.5 3.1 0.00015 21.5 3.1 2.6 1 1 1 2 2 2 1 PAP2 superfamily ARL6IP6 PF15062.6 KFP04112.1 - 0.077 13.1 0.3 0.077 13.1 0.3 2.5 2 1 1 3 3 3 0 Haemopoietic lineage transmembrane helix GST_N_2 PF13409.6 KFP04113.1 - 3.6e-07 30.4 0.0 7.9e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFP04113.1 - 1.8e-06 28.2 0.0 3.7e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFP04113.1 - 3.2e-05 23.9 0.0 0.00017 21.5 0.0 2.1 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFP04113.1 - 5e-05 23.4 0.0 9.5e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFP04113.1 - 5.9e-05 23.3 0.0 0.00013 22.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFP04113.1 - 0.003 17.7 0.0 0.0083 16.3 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KFP04113.1 - 0.082 13.2 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Nsp1 PF11501.8 KFP04113.1 - 0.19 11.8 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 Non structural protein Nsp1 DUF776 PF05604.11 KFP04114.1 - 5.7e-53 180.0 6.2 5.7e-53 180.0 6.2 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF776) SIP1 PF04938.12 KFP04114.1 - 0.0014 18.4 0.2 0.002 17.9 0.2 1.2 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF776 PF05604.11 KFP04115.1 - 1.6e-69 233.9 9.5 2.7e-69 233.2 9.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF776) MORN PF02493.20 KFP04116.1 - 8e-35 116.7 68.5 7.3e-07 28.7 3.2 8.7 9 0 0 9 9 9 8 MORN repeat DUF1180 PF06679.12 KFP04117.1 - 0.0064 16.9 0.3 0.0069 16.8 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) CrgA PF06781.12 KFP04117.1 - 0.31 11.1 1.7 1.4 9.0 1.7 1.9 1 1 0 1 1 1 0 Cell division protein CrgA 7tm_1 PF00001.21 KFP04118.1 - 5.8e-46 156.9 22.7 7e-46 156.7 22.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP04118.1 - 2.1e-07 30.6 20.6 8.8e-07 28.6 20.6 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 KFP04118.1 - 7.5e-06 25.4 19.4 2.8e-05 23.6 19.4 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 KFP04118.1 - 6.4e-05 22.7 17.4 6.4e-05 22.7 17.4 2.3 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx DC_STAMP PF07782.13 KFP04119.1 - 6.9e-35 120.6 0.0 6.9e-35 120.6 0.0 1.8 2 1 0 2 2 2 1 DC-STAMP-like protein EI24 PF07264.11 KFP04119.1 - 0.27 11.4 13.0 0.99 9.6 4.1 2.5 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Na_sulph_symp PF00939.19 KFP04120.1 - 2e-99 333.8 14.8 1.5e-95 321.0 6.6 2.0 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KFP04120.1 - 3e-33 115.3 27.8 6.9e-20 71.4 4.3 3.1 2 1 1 3 3 3 3 Citrate transporter DNA_III_psi PF03603.13 KFP04120.1 - 0.1 12.8 0.2 0.22 11.7 0.2 1.6 1 0 0 1 1 1 0 DNA polymerase III psi subunit Kdo PF06293.14 KFP04121.1 - 1.5e-07 31.0 0.0 1.8e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KFP04121.1 - 6.4e-05 22.4 0.0 7e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KFP04121.1 - 0.0021 18.0 0.0 0.0046 16.9 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFP04121.1 - 0.0067 15.8 0.0 0.0073 15.6 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 KFP04121.1 - 0.0075 15.9 0.0 0.0097 15.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 KFP04121.1 - 0.027 13.8 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase YrbL-PhoP_reg PF10707.9 KFP04121.1 - 0.042 13.4 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.11 KFP04121.1 - 0.054 12.5 0.9 1.9 7.5 0.1 2.0 1 1 1 2 2 2 0 Seadornavirus VP7 Choline_kinase PF01633.20 KFP04121.1 - 0.1 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Sugar_tr PF00083.24 KFP04122.1 - 3e-88 296.6 26.6 1.9e-63 214.9 13.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFP04122.1 - 3.4e-28 98.6 43.8 1.9e-21 76.4 28.3 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Hydrolase PF00702.26 KFP04123.1 - 3.9e-05 24.0 0.0 5.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3544 PF12064.8 KFP04124.1 - 1.2e-96 323.0 20.4 1.2e-96 323.0 20.4 3.3 4 1 1 5 5 5 1 Protein kinase C-binding protein 1 Bromodomain PF00439.25 KFP04124.1 - 1.9e-16 59.9 0.0 5.9e-16 58.3 0.0 1.9 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 KFP04124.1 - 8.8e-07 28.7 13.1 8.8e-07 28.7 13.1 3.7 3 0 0 3 3 3 1 PHD-finger PWWP PF00855.17 KFP04124.1 - 2.2e-06 28.0 0.4 2.2e-06 28.0 0.4 2.5 2 0 0 2 2 2 1 PWWP domain DUF1640 PF07798.11 KFP04124.1 - 0.0002 21.5 2.6 0.0002 21.5 2.6 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1640) zf-MYND PF01753.18 KFP04124.1 - 0.0017 18.4 17.1 0.0017 18.4 17.1 4.2 3 1 0 3 3 3 1 MYND finger DUF3740 PF12548.8 KFP04125.1 - 2.6e-54 183.7 1.7 2.6e-54 183.7 1.7 2.3 3 0 0 3 3 3 1 Sulfatase protein Sulfatase PF00884.23 KFP04125.1 - 1.4e-48 165.9 1.4 2.2e-48 165.3 1.4 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFP04125.1 - 0.012 15.2 0.2 6 6.3 0.0 2.6 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase RAI1 PF08652.11 KFP04125.1 - 0.12 12.6 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease TPR_MLP1_2 PF07926.12 KFP04125.1 - 0.23 11.5 2.8 2.6 8.1 0.1 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF5082 PF16888.5 KFP04125.1 - 0.48 10.7 3.8 2 8.7 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) DEP PF00610.21 KFP04126.1 - 3.7e-42 142.2 0.3 2.9e-21 75.3 0.0 3.4 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGEF PF00621.20 KFP04126.1 - 9.7e-37 127.0 1.7 4.7e-36 124.7 0.1 3.0 3 0 0 3 3 3 1 RhoGEF domain PDZ PF00595.24 KFP04126.1 - 1.6e-08 34.7 0.0 0.0031 17.8 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFP04126.1 - 3.3e-07 30.0 0.0 0.0084 15.9 0.0 3.0 3 0 0 3 3 3 2 PDZ domain PH PF00169.29 KFP04126.1 - 2.9e-05 24.5 0.1 0.00022 21.7 0.2 2.5 2 0 0 2 2 2 1 PH domain PDZ_2 PF13180.6 KFP04126.1 - 0.00065 20.0 0.0 0.65 10.4 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PH_10 PF15411.6 KFP04126.1 - 0.0013 19.0 0.8 0.0049 17.1 0.2 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain UPF1_Zn_bind PF09416.10 KFP04126.1 - 0.0099 15.9 0.0 0.033 14.1 0.0 1.9 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) Sec7 PF01369.20 KFP04127.1 - 2.5e-72 242.4 1.0 6.7e-72 241.0 1.0 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KFP04127.1 - 3.2e-51 173.3 3.4 9.1e-51 171.9 2.2 2.6 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KFP04127.1 - 8.7e-38 129.8 0.1 2.7e-36 124.9 0.1 3.1 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 KFP04127.1 - 1.1e-34 118.1 0.2 1.1e-34 118.1 0.2 5.8 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) CAS_CSE1 PF03378.15 KFP04128.1 - 1.3e-175 584.1 7.2 1.6e-175 583.9 4.8 2.1 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KFP04128.1 - 4.6e-168 558.8 5.2 9.9e-168 557.7 5.2 1.6 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 KFP04128.1 - 3.9e-11 42.7 0.1 3.4e-10 39.7 0.1 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KFP04128.1 - 0.011 15.7 0.0 0.011 15.7 0.0 4.0 3 1 1 4 4 4 0 Exportin 1-like protein PUF PF00806.19 KFP04128.1 - 0.054 13.2 0.1 1.2 9.0 0.0 3.1 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat Arm PF00514.23 KFP04128.1 - 0.11 12.6 1.5 54 4.0 0.1 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KFP04128.1 - 0.21 12.0 0.5 22 5.7 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat DUF3385 PF11865.8 KFP04128.1 - 0.98 9.3 4.9 0.43 10.5 0.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) Staufen_C PF16482.5 KFP04129.1 - 5.2e-55 184.4 2.5 2.2e-49 166.3 0.0 5.0 5 0 0 5 5 5 3 Staufen C-terminal domain dsrm PF00035.26 KFP04129.1 - 4.8e-48 161.7 4.3 2.2e-12 47.5 0.0 4.9 5 0 0 5 5 5 4 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KFP04129.1 - 4.2e-07 30.1 6.1 0.2 12.0 0.0 5.3 5 2 0 5 5 5 3 double strand RNA binding domain from DEAD END PROTEIN 1 LPP20 PF02169.16 KFP04129.1 - 0.041 14.2 0.1 6.2 7.3 0.0 3.3 3 0 0 3 3 3 0 LPP20 lipoprotein Pro-NT_NN PF07421.11 KFP04132.1 - 5.5e-71 238.1 1.5 6.2e-71 237.9 1.5 1.0 1 0 0 1 1 1 1 Neurotensin/neuromedin N precursor Neurokinin_B PF03823.14 KFP04132.1 - 0.12 12.4 0.8 0.37 10.8 0.8 1.8 1 0 0 1 1 1 0 Neurokinin B RA PF00788.23 KFP04133.1 - 3.7e-06 27.5 0.0 1.6e-05 25.5 0.0 2.1 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Homeodomain PF00046.29 KFP04135.1 - 7.2e-24 83.4 6.3 1.6e-23 82.3 6.3 1.6 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 KFP04135.1 - 3.9e-09 36.0 3.2 9.2e-09 34.9 3.2 1.7 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 KFP04135.1 - 0.0011 18.8 0.2 0.0035 17.2 0.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain IQ PF00612.27 KFP04136.1 - 2.9e-06 26.6 0.1 6.1e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif LRR_4 PF12799.7 KFP04137.1 - 9.5e-19 67.2 57.8 4.1e-06 27.0 4.6 8.0 4 2 6 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP04137.1 - 7e-16 57.8 41.2 6.7e-05 22.6 2.1 6.9 3 3 4 7 7 7 5 Leucine rich repeat LRR_9 PF14580.6 KFP04137.1 - 1.1e-06 28.2 7.9 8.7e-06 25.3 0.3 4.8 3 2 1 4 4 4 3 Leucine-rich repeat IQ PF00612.27 KFP04137.1 - 0.00034 20.2 0.1 0.00085 18.9 0.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif CRISPR_Cas2 PF09827.9 KFP04137.1 - 0.04 14.1 0.2 0.04 14.1 0.2 2.7 2 0 0 2 2 2 0 CRISPR associated protein Cas2 SNF PF00209.18 KFP04138.1 - 5.6e-225 748.0 30.3 6.9e-225 747.7 30.3 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Tmemb_18A PF09771.9 KFP04138.1 - 0.53 10.7 0.1 0.53 10.7 0.1 2.8 3 0 0 3 3 3 0 Transmembrane protein 188 BNIP3 PF06553.12 KFP04139.1 - 2.4e-19 69.8 0.1 4.1e-19 69.0 0.1 1.5 1 1 0 1 1 1 1 BNIP3 CUE PF02845.16 KFP04140.1 - 1.2e-10 40.9 0.0 2.3e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 CUE domain 7tm_4 PF13853.6 KFP04142.1 - 6.4e-45 154.0 21.0 7.2e-45 153.9 21.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP04142.1 - 1.9e-27 96.3 24.0 2.4e-27 95.9 24.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Bac_export_2 PF01312.19 KFP04142.1 - 0.038 13.2 5.9 0.049 12.8 5.9 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family 7tm_4 PF13853.6 KFP04143.1 - 3.2e-54 184.5 12.5 3.7e-54 184.3 12.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP04143.1 - 1.6e-27 96.5 15.8 2.1e-27 96.1 15.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4293 PF14126.6 KFP04143.1 - 0.014 15.7 0.2 0.014 15.7 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) 7tm_4 PF13853.6 KFP04144.1 - 6.5e-56 190.1 25.5 7.4e-56 189.9 25.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP04144.1 - 2e-30 106.0 29.3 2.6e-30 105.6 29.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP04145.1 - 2.3e-55 188.3 17.2 2.7e-55 188.1 17.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP04145.1 - 1.3e-25 90.3 19.0 1.7e-25 89.9 19.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP04145.1 - 0.043 13.2 20.8 0.19 11.1 13.3 2.1 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx PNTB_4TM PF12769.7 KFP04145.1 - 2.3 8.7 9.9 0.12 12.8 2.7 2.4 2 1 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch 7tm_4 PF13853.6 KFP04146.1 - 3.1e-54 184.6 18.2 3.5e-54 184.4 18.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP04146.1 - 4.3e-25 88.5 19.6 5.8e-25 88.1 19.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP04147.1 - 1e-53 182.9 11.4 1.2e-53 182.7 11.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP04147.1 - 1.3e-27 96.8 15.2 1.7e-27 96.4 15.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PRY PF13765.6 KFP04148.1 - 2.9e-16 58.8 0.0 4.5e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.28 KFP04148.1 - 1e-11 45.0 0.1 1.3e-11 44.7 0.1 1.1 1 0 0 1 1 1 1 SPRY domain GNT-I PF03071.15 KFP04149.1 - 7.7e-172 571.9 0.0 8.9e-171 568.4 0.0 1.9 1 1 0 2 2 2 1 GNT-I family Glyco_tranf_2_3 PF13641.6 KFP04149.1 - 0.0035 17.3 0.2 0.024 14.6 0.1 2.5 2 1 0 2 2 2 1 Glycosyltransferase like family 2 7tm_1 PF00001.21 KFP04150.1 - 2e-24 86.3 11.9 2.3e-24 86.2 11.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFP04150.1 - 8e-06 25.4 6.5 1.1e-05 25.0 6.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv TAS2R PF05296.13 KFP04150.1 - 0.00011 21.4 0.7 0.00013 21.2 0.7 1.1 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) BCD PF15461.6 KFP04150.1 - 0.002 17.7 3.0 0.0021 17.6 2.1 1.4 1 1 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase DUF2975 PF11188.8 KFP04150.1 - 0.004 17.0 3.5 0.0054 16.6 3.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2975) HemY_N PF07219.13 KFP04150.1 - 1.6 9.0 5.4 1.4 9.2 0.2 2.4 1 1 1 2 2 2 0 HemY protein N-terminus GDP_Man_Dehyd PF16363.5 KFP04151.1 - 1.2e-35 123.5 1.0 5.7e-23 81.8 0.0 3.8 2 2 1 3 3 3 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFP04151.1 - 8.3e-33 113.8 1.1 9e-21 74.4 0.0 3.2 2 1 1 3 3 3 3 NAD dependent epimerase/dehydratase family UXS1_N PF11803.8 KFP04151.1 - 1.4e-23 83.0 0.1 2.8e-23 82.1 0.1 1.5 1 0 0 1 1 1 1 UDP-glucuronate decarboxylase N-terminal RmlD_sub_bind PF04321.17 KFP04151.1 - 0.00017 20.8 0.0 0.21 10.7 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain 3Beta_HSD PF01073.19 KFP04151.1 - 0.0003 19.9 0.2 0.0047 16.0 0.1 2.6 3 1 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KFP04151.1 - 0.0011 18.2 1.5 0.18 10.9 0.1 2.9 3 1 1 4 4 4 2 Male sterility protein Polysacc_synt_2 PF02719.15 KFP04151.1 - 0.0028 16.8 0.2 0.73 8.9 0.0 2.3 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Glyco_transf_4 PF13439.6 KFP04151.1 - 0.2 11.7 0.5 3 7.8 0.1 2.8 3 1 1 4 4 4 0 Glycosyltransferase Family 4 Augurin PF15187.6 KFP04152.1 - 1.9e-51 173.1 3.2 2e-51 172.9 3.2 1.0 1 0 0 1 1 1 1 Oesophageal cancer-related gene 4 SH3_1 PF00018.28 KFP04153.1 - 3.1e-42 142.0 10.0 7.1e-14 51.1 0.1 4.7 5 0 0 5 5 5 3 SH3 domain SH3_9 PF14604.6 KFP04153.1 - 1.1e-39 134.1 2.8 1.7e-14 53.4 0.1 3.8 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 KFP04153.1 - 9.2e-28 95.7 6.9 1.8e-09 37.2 0.2 4.4 4 1 1 5 5 5 3 Variant SH3 domain SH2 PF00017.24 KFP04153.1 - 3.4e-22 78.3 0.0 6.7e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SH3_3 PF08239.11 KFP04153.1 - 3e-09 37.0 9.6 0.0029 17.9 0.5 3.5 3 0 0 3 3 3 3 Bacterial SH3 domain SH3_10 PF17902.1 KFP04153.1 - 6.5e-07 29.3 3.5 0.0014 18.7 0.3 3.0 3 0 0 3 3 3 2 SH3 domain hSH3 PF14603.6 KFP04153.1 - 3.2e-05 24.3 0.0 0.011 16.2 0.0 2.6 2 0 0 2 2 2 1 Helically-extended SH3 domain SH2_2 PF14633.6 KFP04153.1 - 0.0051 16.2 0.1 0.025 14.0 0.1 1.8 1 1 0 1 1 1 1 SH2 domain DUF5350 PF17299.2 KFP04153.1 - 0.15 12.5 3.3 1.4 9.4 0.2 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5350) SH3_4 PF06347.13 KFP04153.1 - 0.84 9.5 4.1 16 5.5 0.8 2.8 2 0 0 2 2 2 0 Bacterial SH3 domain LIM PF00412.22 KFP04154.1 - 2.3e-47 159.0 70.0 7e-13 48.6 7.4 5.1 5 0 0 5 5 5 5 LIM domain zf-ribbon_3 PF13248.6 KFP04154.1 - 0.057 12.9 0.1 0.057 12.9 0.1 8.6 11 1 0 11 11 11 0 zinc-ribbon domain Sgf11 PF08209.11 KFP04154.1 - 0.16 11.6 0.3 0.16 11.6 0.3 9.0 10 0 0 10 10 10 0 Sgf11 (transcriptional regulation protein) Ashwin PF15323.6 KFP04155.1 - 5.7e-71 239.1 9.9 6.3e-71 238.9 9.9 1.0 1 0 0 1 1 1 1 Developmental protein Vps39_2 PF10367.9 KFP04156.1 - 3e-28 98.5 0.0 7.7e-28 97.1 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KFP04156.1 - 5.7e-27 94.1 7.2 8.8e-27 93.5 1.5 3.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 KFP04156.1 - 2.2e-14 53.5 14.5 3.3e-09 36.7 5.1 2.5 2 0 0 2 2 2 2 Region in Clathrin and VPS CNH PF00780.22 KFP04156.1 - 8.6e-13 48.5 0.2 2.4e-12 47.0 0.1 1.8 2 0 0 2 2 2 1 CNH domain TPR_2 PF07719.17 KFP04156.1 - 0.54 10.5 4.7 5.3 7.4 0.4 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFP04156.1 - 4.8 7.2 6.4 50 4.0 0.4 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S9 PF00380.19 KFP04157.1 - 1.4e-35 122.4 0.1 2.4e-35 121.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Claudin_2 PF13903.6 KFP04159.1 - 6.4e-50 169.6 7.6 7.3e-50 169.4 7.6 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFP04159.1 - 0.0002 21.3 9.0 0.086 12.7 4.8 2.2 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family DUF4538 PF15061.6 KFP04159.1 - 4.9 7.0 11.1 7.9 6.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4538) MFS_1 PF07690.16 KFP04160.1 - 2.1e-39 135.5 22.4 2.6e-39 135.2 22.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP04160.1 - 5.5e-10 38.7 2.4 5.5e-10 38.7 2.4 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 KFP04160.1 - 0.0001 21.3 14.0 0.00068 18.6 14.0 1.9 1 1 0 1 1 1 1 MFS_1 like family MFS_4 PF06779.14 KFP04160.1 - 0.00039 19.8 5.1 0.00039 19.8 5.1 2.5 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB Na_H_Exchanger PF00999.21 KFP04161.1 - 1.1e-90 304.2 41.3 1.3e-90 304.0 41.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.21 KFP04162.1 - 5.7e-84 282.1 36.6 6.7e-84 281.9 36.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NEXCaM_BD PF16644.5 KFP04162.1 - 3.3e-36 124.0 4.2 3.3e-36 124.0 4.2 1.7 2 0 0 2 2 2 1 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin Tim17 PF02466.19 KFP04162.1 - 0.023 15.1 2.6 0.029 14.7 0.9 2.2 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family TIR PF01582.20 KFP04163.1 - 9.4e-37 126.5 0.0 2.1e-36 125.4 0.0 1.6 1 0 0 1 1 1 1 TIR domain Ig_6 PF18452.1 KFP04163.1 - 1e-24 85.8 0.5 2.7e-21 74.8 0.2 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 KFP04163.1 - 7e-16 58.6 2.6 8.2e-06 26.3 0.0 3.7 3 1 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFP04163.1 - 2e-12 47.1 4.1 0.00025 21.2 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFP04163.1 - 7.6e-11 41.9 2.1 0.002 18.1 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP04163.1 - 5.9e-10 39.3 2.7 0.0064 16.8 0.6 3.5 3 0 0 3 3 3 3 Immunoglobulin domain TIR_2 PF13676.6 KFP04163.1 - 8.4e-10 39.3 0.0 1.8e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 TIR domain C1-set PF07654.15 KFP04163.1 - 0.0012 19.2 0.5 2.1 8.8 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin C1-set domain Ig_5 PF16681.5 KFP04163.1 - 0.0023 18.3 4.1 3.5 8.1 0.1 4.2 3 1 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set_CD47 PF08204.11 KFP04163.1 - 0.0087 16.0 1.3 0.049 13.6 0.1 2.6 3 0 0 3 3 3 1 CD47 immunoglobulin-like domain Ig_4 PF16680.5 KFP04163.1 - 2.1 8.7 9.0 0.28 11.4 0.4 3.6 3 2 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain TIR PF01582.20 KFP04164.1 - 2.5e-37 128.4 1.9 2.7e-37 128.3 0.0 2.0 2 1 0 2 2 2 1 TIR domain Ig_2 PF13895.6 KFP04164.1 - 4.2e-12 46.2 5.6 2.6e-07 30.8 0.3 3.7 3 1 0 3 3 3 2 Immunoglobulin domain Ig_6 PF18452.1 KFP04164.1 - 1.6e-10 40.3 0.1 0.0001 21.8 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin domain TIR_2 PF13676.6 KFP04164.1 - 5.3e-09 36.7 0.0 1.6e-08 35.2 0.0 1.8 2 0 0 2 2 2 1 TIR domain Ig_3 PF13927.6 KFP04164.1 - 9.4e-08 32.6 8.9 0.01 16.4 0.3 4.1 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 KFP04164.1 - 1.5e-05 25.1 8.1 0.25 11.5 0.1 5.3 3 2 2 5 5 5 1 Immunoglobulin V-set domain ig PF00047.25 KFP04164.1 - 0.00013 22.1 3.7 0.84 9.9 0.2 3.7 3 0 0 3 3 3 2 Immunoglobulin domain Ig_5 PF16681.5 KFP04164.1 - 0.00037 20.8 5.4 0.003 17.9 0.5 3.2 3 0 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFP04164.1 - 0.0011 19.2 0.6 0.0011 19.2 0.6 2.9 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain I-set PF07679.16 KFP04164.1 - 0.0025 17.9 7.6 0.78 9.9 0.2 4.0 5 0 0 5 5 5 2 Immunoglobulin I-set domain Mqo PF06039.15 KFP04164.1 - 0.055 12.0 1.0 0.081 11.5 0.1 1.6 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) TIR PF01582.20 KFP04165.1 - 5.1e-31 107.8 0.4 7.4e-31 107.3 0.4 1.2 1 0 0 1 1 1 1 TIR domain Ig_3 PF13927.6 KFP04165.1 - 5e-20 71.9 0.2 2.1e-07 31.4 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFP04165.1 - 3.3e-19 69.0 2.3 1e-06 29.0 0.4 3.4 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFP04165.1 - 1.3e-13 50.9 7.5 1.2e-05 25.4 0.2 3.7 4 0 0 4 4 3 3 Immunoglobulin domain I-set PF07679.16 KFP04165.1 - 2.4e-13 50.0 2.5 4.6e-05 23.4 0.0 3.7 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_6 PF18452.1 KFP04165.1 - 5.7e-13 48.2 3.4 8.9e-12 44.4 0.1 3.1 3 0 0 3 3 3 1 Immunoglobulin domain V-set PF07686.17 KFP04165.1 - 1.2e-05 25.5 9.2 0.16 12.1 0.1 5.2 4 3 1 5 5 5 2 Immunoglobulin V-set domain TIR_2 PF13676.6 KFP04165.1 - 5.3e-05 23.8 0.1 0.0001 22.9 0.1 1.4 1 0 0 1 1 1 1 TIR domain V-set_CD47 PF08204.11 KFP04165.1 - 0.0029 17.6 1.0 0.45 10.5 0.0 3.1 3 0 0 3 3 3 1 CD47 immunoglobulin-like domain Ig_4 PF16680.5 KFP04165.1 - 0.071 13.4 1.9 3.1 8.1 0.1 3.4 3 1 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain C2-set PF05790.15 KFP04165.1 - 0.15 12.3 0.0 35 4.7 0.0 2.8 2 0 0 2 2 2 0 Immunoglobulin C2-set domain BiPBP_C PF06832.12 KFP04165.1 - 0.16 12.0 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family TIR PF01582.20 KFP04166.1 - 7.4e-32 110.6 0.0 1.2e-31 109.8 0.0 1.3 1 0 0 1 1 1 1 TIR domain Ig_3 PF13927.6 KFP04166.1 - 1.6e-20 73.4 0.4 3.5e-07 30.7 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFP04166.1 - 1.5e-19 69.8 0.2 1.8e-05 24.7 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP04166.1 - 2.7e-18 66.1 1.3 8.5e-08 32.4 0.1 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Ig_6 PF18452.1 KFP04166.1 - 9.6e-13 47.5 0.1 2.2e-09 36.7 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP04166.1 - 3.4e-11 43.2 0.8 0.024 14.8 0.0 4.1 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFP04166.1 - 5.2e-08 33.0 8.3 0.097 12.9 0.2 5.4 3 2 2 5 5 5 4 Immunoglobulin V-set domain Ig_5 PF16681.5 KFP04166.1 - 0.0004 20.7 0.6 3.4 8.2 0.0 4.0 3 1 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain TIR_2 PF13676.6 KFP04166.1 - 0.017 15.8 0.0 0.034 14.7 0.0 1.5 1 0 0 1 1 1 0 TIR domain Lep_receptor_Ig PF06328.11 KFP04166.1 - 0.022 14.7 0.1 2.1 8.3 0.0 3.4 3 0 0 3 3 3 0 Ig-like C2-type domain Adeno_E3_CR1 PF02440.15 KFP04166.1 - 0.08 12.7 4.8 0.11 12.2 0.3 3.1 3 0 0 3 3 3 0 Adenovirus E3 region protein CR1 TIR PF01582.20 KFP04167.1 - 7.3e-36 123.6 0.0 1.1e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 TIR domain Ig_3 PF13927.6 KFP04167.1 - 1.7e-16 60.5 0.0 0.00062 20.3 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFP04167.1 - 1.9e-15 56.9 0.2 1.7e-06 28.3 0.0 3.4 3 1 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFP04167.1 - 3.9e-14 52.5 0.0 0.00015 21.7 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 KFP04167.1 - 9.4e-12 44.9 0.0 0.00023 21.3 0.0 3.5 3 1 0 3 3 3 3 Immunoglobulin domain Ig_6 PF18452.1 KFP04167.1 - 1.4e-11 43.7 0.1 7.6e-07 28.6 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFP04167.1 - 7.8e-08 32.5 4.6 0.059 13.5 2.2 4.7 3 2 1 4 4 4 3 Immunoglobulin V-set domain TIR_2 PF13676.6 KFP04167.1 - 0.00074 20.1 0.0 0.0024 18.5 0.0 1.8 1 1 0 1 1 1 1 TIR domain Izumo-Ig PF16706.5 KFP04167.1 - 0.026 14.6 0.0 3 8.0 0.0 2.6 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Arm-DNA-bind_2 PF12167.8 KFP04167.1 - 0.13 12.2 0.3 11 6.0 0.0 3.0 3 0 0 3 3 3 0 Arm DNA-binding domain Ig_6 PF18452.1 KFP04168.1 - 9.1e-16 57.2 0.0 6.8e-13 48.0 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 KFP04168.1 - 1.8e-15 57.3 0.2 0.0027 18.3 0.1 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFP04168.1 - 2.6e-13 50.1 0.0 0.00028 21.2 0.0 3.5 3 1 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFP04168.1 - 3.7e-11 43.0 0.2 0.0029 17.7 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFP04168.1 - 3.9e-10 39.7 0.0 0.0082 16.2 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin I-set domain V-set PF07686.17 KFP04168.1 - 3.8e-09 36.7 2.5 0.0043 17.2 0.0 4.3 3 2 0 3 3 3 3 Immunoglobulin V-set domain DUF4516 PF14990.6 KFP04168.1 - 0.012 15.4 1.2 0.023 14.4 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) Izumo-Ig PF16706.5 KFP04168.1 - 0.017 15.2 0.1 0.66 10.1 0.0 2.6 2 1 0 2 2 2 0 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 KFP04168.1 - 0.029 14.6 0.1 6.2 7.2 0.1 3.4 3 1 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFP04168.1 - 0.17 12.3 3.6 4.9 7.6 0.1 4.0 3 3 0 3 3 3 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain CNH PF00780.22 KFP04169.1 - 3.7e-60 203.9 0.0 5.6e-60 203.3 0.0 1.3 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.25 KFP04169.1 - 3.9e-55 187.1 0.0 7.2e-55 186.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP04169.1 - 1.3e-40 139.4 0.0 2.4e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Borrelia_P83 PF05262.11 KFP04169.1 - 0.17 10.4 25.0 0.28 9.6 25.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Pyrid_oxidase_2 PF13883.6 KFP04170.1 - 6.1e-46 156.5 0.0 6.7e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 KFP04170.1 - 0.0002 21.5 0.0 0.00027 21.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase zf-RING_2 PF13639.6 KFP04171.1 - 1e-12 48.2 8.1 1.6e-12 47.5 8.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFP04171.1 - 2.8e-10 39.8 3.1 5.3e-10 38.9 3.1 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFP04171.1 - 1.6e-09 37.5 7.7 2.5e-09 36.8 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFP04171.1 - 3.5e-08 33.6 5.6 9e-08 32.3 5.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFP04171.1 - 1.6e-07 31.1 7.3 2.6e-07 30.4 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP04171.1 - 4.9e-07 29.6 5.0 7.6e-07 29.0 5.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP04171.1 - 1.1e-06 28.4 5.0 1.9e-06 27.6 5.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 PA PF02225.22 KFP04171.1 - 8.1e-06 25.8 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-RING_UBOX PF13445.6 KFP04171.1 - 9.2e-06 25.6 5.0 1.6e-05 24.8 5.0 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFP04171.1 - 0.00013 21.7 4.8 0.0002 21.1 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CrgA PF06781.12 KFP04171.1 - 0.0029 17.6 1.8 0.0036 17.3 0.5 1.7 2 0 0 2 2 2 1 Cell division protein CrgA PspB PF06667.12 KFP04171.1 - 0.0093 16.0 1.0 0.014 15.4 0.1 1.8 2 0 0 2 2 2 1 Phage shock protein B zf-ANAPC11 PF12861.7 KFP04171.1 - 0.029 14.4 4.4 0.059 13.4 4.4 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFP04171.1 - 0.044 13.4 5.6 0.13 11.9 5.6 1.8 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 KFP04171.1 - 0.045 13.8 5.6 0.11 12.5 5.6 1.7 1 0 0 1 1 1 0 Zinc-finger CDC24_OB3 PF17244.2 KFP04171.1 - 0.089 12.5 0.2 0.13 12.0 0.2 1.2 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 PHD PF00628.29 KFP04171.1 - 1.2 9.0 4.7 2.7 8.0 4.7 1.6 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 KFP04171.1 - 2.9 8.1 5.2 16 5.7 5.5 2.1 1 1 1 2 2 2 0 FANCL C-terminal domain RINGv PF12906.7 KFP04171.1 - 5.4 7.2 6.3 11 6.2 6.3 1.5 1 0 0 1 1 1 0 RING-variant domain CNOT11 PF10155.9 KFP04172.1 - 4.6e-55 185.1 6.3 6.9e-55 184.5 6.3 1.3 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 Ribosomal_L31e PF01198.19 KFP04173.1 - 2.5e-53 178.2 1.0 3.3e-53 177.9 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e Vsr PF03852.15 KFP04173.1 - 0.0067 16.3 0.1 0.014 15.2 0.0 1.6 1 1 1 2 2 2 1 DNA mismatch endonuclease Vsr PAS_11 PF14598.6 KFP04174.1 - 1.1e-20 73.9 0.6 1.2e-19 70.5 0.0 3.1 4 0 0 4 4 4 1 PAS domain PAS_3 PF08447.12 KFP04174.1 - 1.3e-16 60.6 0.1 9.5e-15 54.7 0.1 2.5 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 KFP04174.1 - 3.1e-11 43.3 0.0 6.3e-08 32.6 0.0 2.8 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 KFP04174.1 - 1.6e-09 37.6 0.4 3.7e-09 36.4 0.4 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 KFP04174.1 - 0.027 14.7 0.0 0.08 13.2 0.0 1.8 1 0 0 1 1 1 0 PAS domain Phosducin PF02114.16 KFP04175.1 - 1e-16 60.7 0.9 1.3e-16 60.4 0.6 1.3 1 1 0 1 1 1 1 Phosducin UPF0175 PF03683.13 KFP04175.1 - 0.0011 18.7 3.7 0.0017 18.0 0.8 2.7 3 1 0 4 4 4 1 Uncharacterised protein family (UPF0175) Histone PF00125.24 KFP04176.1 - 1.1e-13 51.7 0.0 1.3e-13 51.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KFP04176.1 - 3.2e-13 49.1 0.4 7.4e-13 48.0 0.0 1.7 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KFP04176.1 - 0.00011 22.4 0.0 0.00016 21.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Sulfotransfer_2 PF03567.14 KFP04177.1 - 1.1e-51 176.2 0.1 1.3e-51 175.9 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family DUF1075 PF06388.11 KFP04177.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1075) LON_substr_bdg PF02190.16 KFP04178.1 - 8.9e-23 81.3 0.0 1.5e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KFP04178.1 - 9.2e-11 41.4 15.8 2.3e-10 40.1 15.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP04178.1 - 7.9e-10 38.4 9.5 1.5e-09 37.6 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP04178.1 - 3e-07 30.2 14.7 7.4e-07 28.9 14.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP04178.1 - 3e-07 30.3 8.6 3e-07 30.3 8.6 2.8 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFP04178.1 - 9.1e-07 29.1 14.8 9.1e-07 29.1 14.8 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KFP04178.1 - 5.6e-06 26.4 13.3 1.3e-05 25.2 13.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFP04178.1 - 5.7e-06 26.1 11.3 1.1e-05 25.2 11.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFP04178.1 - 8.6e-06 25.6 13.4 1.8e-05 24.6 13.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain U-box PF04564.15 KFP04178.1 - 0.00074 19.6 0.0 0.0016 18.6 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-rbx1 PF12678.7 KFP04178.1 - 0.0014 18.8 10.4 0.0036 17.5 10.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KFP04178.1 - 0.0021 18.2 7.9 0.0042 17.2 7.9 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KFP04178.1 - 0.04 13.8 6.4 0.084 12.8 6.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KFP04178.1 - 0.043 13.6 9.2 0.11 12.3 9.2 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain AF-4 PF05110.13 KFP04179.1 - 1.7e-72 245.1 19.3 5.8e-48 163.9 6.2 2.0 1 1 1 2 2 2 2 AF-4 proto-oncoprotein BRD4_CDT PF17105.5 KFP04179.1 - 0.47 10.1 2.1 0.92 9.2 2.1 1.5 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 AF-4 PF05110.13 KFP04180.1 - 1.1e-77 262.4 46.0 1.1e-47 163.0 34.3 2.0 1 1 1 2 2 2 2 AF-4 proto-oncoprotein MACPF PF01823.19 KFP04180.1 - 0.75 9.9 9.9 0.021 14.9 3.3 1.7 2 0 0 2 2 2 0 MAC/Perforin domain IMS PF00817.20 KFP04181.1 - 2.1e-43 147.9 0.0 3.9e-43 147.0 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KFP04181.1 - 2e-15 57.5 0.0 4.1e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain REV1_C PF16727.5 KFP04181.1 - 5.3e-14 52.4 0.7 1e-13 51.4 0.7 1.5 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain BRCT_2 PF16589.5 KFP04181.1 - 5.7e-10 39.5 0.0 1.3e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KFP04181.1 - 7.5e-08 32.7 0.0 1.9e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain UBM PF14377.6 KFP04181.1 - 3.2e-07 29.6 4.7 0.0075 15.7 0.2 2.6 2 0 0 2 2 2 2 Ubiquitin binding region LIG3_BRCT PF16759.5 KFP04181.1 - 6.5e-07 29.6 0.0 1.9e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain IMS_HHH PF11798.8 KFP04181.1 - 0.00028 21.0 0.0 0.032 14.6 0.0 2.8 2 0 0 2 2 2 1 IMS family HHH motif PTCB-BRCT PF12738.7 KFP04181.1 - 0.0015 18.5 0.0 0.0036 17.2 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain mCpol PF18182.1 KFP04181.1 - 0.014 15.7 0.0 0.04 14.3 0.0 1.8 1 0 0 1 1 1 0 minimal CRISPR polymerase domain Cdd1 PF11731.8 KFP04181.1 - 0.02 15.2 0.0 0.055 13.7 0.0 1.8 1 0 0 1 1 1 0 Pathogenicity locus DUF1805 PF08827.11 KFP04181.1 - 0.091 13.1 0.0 0.33 11.3 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Thioredoxin PF00085.20 KFP04182.1 - 3.4e-11 43.1 0.1 7.7e-11 41.9 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 KFP04182.1 - 6.2e-09 35.2 0.6 8.1e-09 34.8 0.6 1.1 1 0 0 1 1 1 1 Phosducin eIF-3_zeta PF05091.12 KFP04182.1 - 0.025 13.6 0.9 0.032 13.2 0.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Sds3 PF08598.11 KFP04182.1 - 0.084 12.9 3.5 0.42 10.6 4.4 1.6 2 0 0 2 2 2 0 Sds3-like PSII_Pbs27 PF13326.6 KFP04182.1 - 0.12 12.6 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 Photosystem II Pbs27 BAG PF02179.16 KFP04182.1 - 0.24 11.9 6.0 0.51 10.8 6.0 1.5 1 0 0 1 1 1 0 BAG domain PTPlike_phytase PF14566.6 KFP04182.1 - 0.24 11.5 1.9 0.37 10.9 1.9 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate FapA PF03961.13 KFP04182.1 - 2 7.0 5.6 2.3 6.7 5.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A SLT PF01464.20 KFP04183.1 - 0.0077 15.9 0.0 0.029 14.0 0.0 1.8 2 0 0 2 2 2 1 Transglycosylase SLT domain SLT PF01464.20 KFP04184.1 - 2.3e-06 27.2 0.0 7.2e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 Transglycosylase SLT domain Ribosomal_L30 PF00327.20 KFP04185.1 - 9.2e-15 54.3 1.0 1.3e-14 53.8 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e BPL_LplA_LipB PF03099.19 KFP04186.1 - 0.0049 16.8 0.0 0.023 14.6 0.0 2.0 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family DUF4592 PF15262.6 KFP04187.1 - 2.8e-31 108.9 12.3 3.8e-31 108.5 3.9 3.3 2 2 0 2 2 2 1 Domain of unknown function (DUF4592) Glyco_transf_54 PF04666.13 KFP04189.1 - 4.4e-136 452.5 1.5 6.1e-136 452.0 1.5 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF4750 PF15938.5 KFP04189.1 - 0.27 10.9 1.4 0.64 9.7 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4750) UNC-50 PF05216.13 KFP04190.1 - 2.3e-91 305.3 22.7 2.7e-91 305.1 22.7 1.0 1 0 0 1 1 1 1 UNC-50 family C2 PF00168.30 KFP04191.1 - 0.00098 19.4 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain NHR2 PF08788.11 KFP04191.1 - 0.0061 16.3 0.5 0.21 11.4 0.2 2.8 2 0 0 2 2 2 1 NHR2 domain like TMEM131_like PF12371.8 KFP04192.1 - 1.5e-23 82.8 10.8 2.3e-23 82.2 0.8 4.5 4 0 0 4 4 4 1 Transmembrane protein 131-like ASH PF15780.5 KFP04192.1 - 2.2e-10 40.6 6.4 0.00093 19.4 0.2 7.2 7 0 0 7 7 7 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin fn3_5 PF06280.12 KFP04192.1 - 0.054 14.2 1.1 0.4 11.4 0.7 2.8 2 0 0 2 2 2 0 Fn3-like domain VWA_3 PF13768.6 KFP04193.1 - 0.019 14.9 0.3 0.03 14.3 0.3 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Ion_trans PF00520.31 KFP04194.1 - 9.3e-32 110.2 10.6 1.4e-31 109.6 10.6 1.2 1 0 0 1 1 1 1 Ion transport protein CLZ PF16526.5 KFP04194.1 - 1.1e-29 102.5 5.9 1.1e-29 102.5 5.9 3.1 3 0 0 3 3 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels cNMP_binding PF00027.29 KFP04194.1 - 5.7e-19 68.0 0.0 9.8e-19 67.2 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain RR_TM4-6 PF06459.12 KFP04194.1 - 0.00062 19.7 9.9 0.00062 19.7 9.9 1.8 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 AAA_23 PF13476.6 KFP04194.1 - 0.00091 19.8 16.5 0.013 16.1 8.5 2.4 2 0 0 2 2 2 2 AAA domain CPSF100_C PF13299.6 KFP04194.1 - 0.0036 17.5 5.1 0.0036 17.5 5.1 1.9 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Adaptin_binding PF10199.9 KFP04194.1 - 0.0059 17.2 9.7 0.052 14.2 6.4 2.4 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 DDHD PF02862.17 KFP04194.1 - 0.0074 16.5 0.4 0.013 15.7 0.0 1.6 2 0 0 2 2 1 1 DDHD domain NPR3 PF03666.13 KFP04194.1 - 0.0082 15.0 8.3 0.013 14.4 8.3 1.2 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 KFP04194.1 - 0.015 14.1 2.8 0.023 13.5 2.8 1.3 1 0 0 1 1 1 0 Presenilin MID_MedPIWI PF18296.1 KFP04194.1 - 0.016 15.0 1.4 0.02 14.7 0.2 1.7 2 0 0 2 2 2 0 MID domain of medPIWI Ion_trans_2 PF07885.16 KFP04194.1 - 0.038 14.0 4.3 0.13 12.3 4.3 2.0 1 0 0 1 1 1 0 Ion channel DUF948 PF06103.11 KFP04194.1 - 0.074 13.3 0.6 5.8 7.2 0.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3043 PF11241.8 KFP04194.1 - 0.081 13.0 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF913 PF06025.12 KFP04194.1 - 0.11 11.4 3.8 0.21 10.5 3.8 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SAPS PF04499.15 KFP04194.1 - 0.11 11.2 5.5 0.17 10.6 5.5 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BSMAP PF12280.8 KFP04194.1 - 0.13 12.5 0.9 0.35 11.0 0.9 1.8 1 0 0 1 1 1 0 Brain specific membrane anchored protein Tim54 PF11711.8 KFP04194.1 - 0.23 10.2 14.1 0.4 9.4 14.1 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FAM76 PF16046.5 KFP04194.1 - 0.24 10.7 21.6 0.091 12.1 0.7 2.3 2 0 0 2 2 2 0 FAM76 protein SpoIIP PF07454.11 KFP04194.1 - 0.33 10.4 15.9 0.64 9.4 15.9 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PPL5 PF18168.1 KFP04194.1 - 0.5 9.6 9.0 0.93 8.7 9.0 1.4 1 0 0 1 1 1 0 Prim-pol family 5 Neur_chan_memb PF02932.16 KFP04194.1 - 0.76 9.8 4.7 3.4 7.7 3.5 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF2151 PF10221.9 KFP04194.1 - 0.79 8.2 10.1 1.3 7.6 10.1 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator DUF4820 PF16091.5 KFP04194.1 - 1.4 8.2 7.7 3 7.2 7.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RNA_pol_Rpc4 PF05132.14 KFP04194.1 - 1.4 9.3 16.6 3.4 8.1 16.6 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 TFB6 PF17110.5 KFP04194.1 - 2 8.2 6.8 5.5 6.7 6.8 1.8 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF4637 PF15470.6 KFP04194.1 - 2.7 7.7 12.3 5.4 6.7 12.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) RP-C_C PF11800.8 KFP04194.1 - 2.7 8.0 6.7 0.89 9.6 2.5 2.0 2 0 0 2 2 2 0 Replication protein C C-terminal region PTPRCAP PF15713.5 KFP04194.1 - 3.2 8.0 15.9 8.5 6.7 15.9 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Zip PF02535.22 KFP04194.1 - 3.5 6.7 7.0 6.1 6.0 7.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SpoIIIAH PF12685.7 KFP04194.1 - 4 7.2 19.8 0.039 13.8 7.4 2.6 3 0 0 3 3 3 0 SpoIIIAH-like protein Coilin_N PF15862.5 KFP04194.1 - 4.7 7.0 23.8 0.65 9.8 19.4 1.8 2 0 0 2 2 1 0 Coilin N-terminus CSRNP_N PF16019.5 KFP04194.1 - 4.9 7.0 9.8 10 6.0 9.1 1.9 2 0 0 2 2 1 0 Cysteine/serine-rich nuclear protein N-terminus DUF1980 PF09323.10 KFP04194.1 - 5.3 6.9 5.8 25 4.7 6.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) CDC45 PF02724.14 KFP04194.1 - 6.7 4.9 21.9 1 7.6 15.1 2.1 2 0 0 2 2 2 0 CDC45-like protein TMEM214 PF10151.9 KFP04194.1 - 6.8 5.0 16.3 12 4.2 16.3 1.3 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DUF3464 PF11947.8 KFP04194.1 - 7.4 6.3 12.8 16 5.2 12.8 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Amidinotransf PF02274.17 KFP04194.1 - 8.6 5.3 10.9 5.5 6.0 6.0 2.2 2 0 0 2 2 2 0 Amidinotransferase TRAP_alpha PF03896.16 KFP04194.1 - 9.7 5.3 12.3 19 4.4 12.3 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit HECT PF00632.25 KFP04195.1 - 1.2e-93 314.0 0.2 2.5e-93 312.9 0.2 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 KFP04195.1 - 5.4e-18 65.0 3.5 1.5e-17 63.6 3.5 1.8 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A LPD11 PF18824.1 KFP04195.1 - 0.012 15.7 0.4 9.6 6.4 0.0 3.5 4 0 0 4 4 4 0 Large polyvalent protein-associated domain 11 PhoLip_ATPase_C PF16212.5 KFP04197.1 - 1.1e-78 264.4 23.7 1.1e-78 264.4 23.7 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFP04197.1 - 7.3e-20 70.4 4.1 2.6e-19 68.7 4.1 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFP04197.1 - 3.2e-12 47.2 0.0 1.2e-05 25.7 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFP04197.1 - 6.7e-09 35.7 0.0 7.5e-08 32.4 0.0 2.7 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFP04197.1 - 0.0013 18.5 1.7 0.0022 17.8 0.2 2.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Yae1_N PF09811.9 KFP04198.1 - 7.7e-18 63.9 63.5 1.8e+04 -28.3 63.5 6.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Neur_chan_memb PF02932.16 KFP04199.1 - 5.5e-51 173.9 0.3 1e-50 173.0 0.3 1.4 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFP04199.1 - 2.9e-38 131.5 0.0 4.5e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain OAD_gamma PF04277.13 KFP04199.1 - 0.079 13.6 0.1 0.19 12.3 0.0 1.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Neur_chan_LBD PF02931.23 KFP04200.1 - 3.1e-49 167.3 0.0 4.4e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP04200.1 - 7.4e-39 134.2 4.7 1.3e-32 113.8 2.8 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region CytochromB561_N PF09786.9 KFP04200.1 - 0.0007 18.7 1.8 0.00095 18.3 1.8 1.1 1 0 0 1 1 1 1 Cytochrome B561, N terminal Neur_chan_LBD PF02931.23 KFP04201.1 - 2e-43 148.3 2.7 2.7e-43 147.9 2.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP04201.1 - 4.4e-40 138.2 6.6 1e-39 137.1 6.6 1.6 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region YesK PF14150.6 KFP04201.1 - 1.7 8.9 5.0 12 6.2 0.8 3.1 2 1 1 3 3 3 0 YesK-like protein CitMHS PF03600.16 KFP04202.1 - 4.2e-57 193.6 17.5 4.2e-57 193.6 17.5 2.2 2 1 1 3 3 3 1 Citrate transporter Na_sulph_symp PF00939.19 KFP04202.1 - 1.9e-15 56.9 33.3 5.8e-11 42.1 13.7 2.7 2 1 0 2 2 2 2 Sodium:sulfate symporter transmembrane region ArsB PF02040.15 KFP04202.1 - 3.1e-08 33.4 23.3 8.8e-05 22.0 5.2 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein MatC_N PF07158.11 KFP04202.1 - 0.01 15.9 12.2 0.01 15.9 12.2 3.0 3 0 0 3 3 3 0 Dicarboxylate carrier protein MatC N-terminus YIF1 PF03878.15 KFP04202.1 - 7.6 6.0 9.8 2.1 7.8 0.0 3.2 3 0 0 3 3 3 0 YIF1 RCC1 PF00415.18 KFP04203.1 - 2.4e-231 748.5 85.9 2.7e-15 56.7 0.1 21.7 21 0 0 21 21 21 19 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFP04203.1 - 1.3e-92 302.1 111.7 9.2e-08 31.7 0.3 21.9 22 0 0 22 22 22 16 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.25 KFP04203.1 - 2e-60 204.9 0.0 3.7e-60 204.0 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Cul7 PF11515.8 KFP04203.1 - 3.5e-35 120.1 2.4 4.8e-35 119.7 0.8 2.1 2 0 0 2 2 2 1 Mouse development and cellular proliferation protein Cullin-7 MIB_HERC2 PF06701.13 KFP04203.1 - 5.5e-22 77.8 5.0 5.5e-22 77.8 5.0 5.8 7 0 0 7 7 7 1 Mib_herc2 Cyt-b5 PF00173.28 KFP04203.1 - 2.5e-10 40.3 0.0 9.3e-10 38.5 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain ZZ PF00569.17 KFP04203.1 - 9e-10 38.2 7.0 2.1e-09 37.0 7.0 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type ANAPC10 PF03256.16 KFP04203.1 - 4e-06 26.6 0.0 7.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) SH3_15 PF18346.1 KFP04203.1 - 6.7e-06 26.3 5.3 0.00014 22.1 0.6 3.6 3 0 0 3 3 3 1 Mind bomb SH3 repeat domain Hira PF07569.11 KFP04203.1 - 0.02 14.6 0.6 26 4.4 0.0 5.5 6 0 0 6 6 6 0 TUP1-like enhancer of split Med3 PF11593.8 KFP04203.1 - 0.094 11.9 0.3 0.23 10.6 0.3 1.6 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ubie_methyltran PF01209.18 KFP04203.1 - 0.11 11.8 0.7 20 4.4 0.0 3.7 4 0 0 4 4 4 0 ubiE/COQ5 methyltransferase family zf-UBR PF02207.20 KFP04203.1 - 0.45 10.7 5.3 0.22 11.7 2.2 2.1 2 0 0 2 2 1 0 Putative zinc finger in N-recognin (UBR box) Mg_trans_NIPA PF05653.14 KFP04204.1 - 2.2e-70 237.1 14.9 2.5e-70 236.9 14.9 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KFP04204.1 - 0.0042 17.3 4.5 0.0042 17.3 4.5 3.2 2 1 1 3 3 3 2 EamA-like transporter family DUF3611 PF12263.8 KFP04204.1 - 0.048 13.5 0.2 0.048 13.5 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3611) Acyl_transf_3 PF01757.22 KFP04204.1 - 0.51 9.4 14.1 0.61 9.1 10.8 2.1 1 1 1 2 2 2 0 Acyltransferase family DUF2973 PF11189.8 KFP04204.1 - 1.4 9.0 3.3 0.49 10.5 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) Mg_trans_NIPA PF05653.14 KFP04205.1 - 1.8e-148 493.4 17.1 2.1e-148 493.2 17.1 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KFP04205.1 - 3.2e-09 37.1 4.0 3.2e-09 37.1 4.0 4.1 3 1 0 3 3 3 1 EamA-like transporter family DUF2627 PF11118.8 KFP04205.1 - 0.25 12.0 3.2 13 6.5 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) FragX_IP PF05994.11 KFP04206.1 - 0 1329.6 5.8 0 1329.6 5.8 1.7 2 0 0 2 2 2 1 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 KFP04206.1 - 4e-08 32.9 6.0 1e-07 31.6 6.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) zf-CW PF07496.15 KFP04206.1 - 0.099 12.7 0.4 0.25 11.4 0.4 1.7 1 0 0 1 1 1 0 CW-type Zinc Finger fn3 PF00041.21 KFP04207.1 - 3.1e-05 24.2 0.2 5.3e-05 23.5 0.2 1.4 1 0 0 1 1 1 1 Fibronectin type III domain FAM163 PF15069.6 KFP04207.1 - 0.0016 18.9 0.2 0.0032 17.9 0.0 1.7 2 0 0 2 2 2 1 FAM163 family MLANA PF14991.6 KFP04207.1 - 0.019 15.2 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A Interfer-bind PF09294.10 KFP04207.1 - 0.037 14.4 0.4 0.067 13.5 0.4 1.4 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III Afaf PF15339.6 KFP04207.1 - 0.044 13.5 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Acrosome formation-associated factor Pur_ac_phosph_N PF16656.5 KFP04207.1 - 0.049 14.2 0.2 0.074 13.6 0.2 1.3 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain DUF2207 PF09972.9 KFP04207.1 - 0.16 10.7 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) GCP_C_terminal PF04130.13 KFP04208.1 - 3.5e-40 138.4 10.2 3.5e-40 138.4 8.5 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KFP04208.1 - 2e-27 96.6 2.3 2e-27 96.6 2.3 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP5-Mod21 PF14609.6 KFP04208.1 - 7.4e-05 21.3 1.4 0.00028 19.4 0.1 2.4 2 0 0 2 2 2 1 gamma-Tubulin ring complex non-core subunit mod21 DUF5601 PF18151.1 KFP04208.1 - 0.054 13.8 0.7 1.7 9.0 0.1 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) TBCC PF07986.12 KFP04209.1 - 2.8e-46 156.1 5.4 4.6e-46 155.4 5.4 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 KFP04209.1 - 0.00072 19.2 2.8 0.0014 18.3 2.8 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal NDK PF00334.19 KFP04209.1 - 0.00085 19.3 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Nucleoside diphosphate kinase SGL PF08450.12 KFP04210.1 - 4.9e-75 252.3 0.1 5.6e-75 252.1 0.1 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 KFP04210.1 - 0.037 14.2 0.0 0.33 11.3 0.0 2.6 2 0 0 2 2 2 0 Two component regulator propeller NHL PF01436.21 KFP04210.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 NHL repeat SGL PF08450.12 KFP04211.1 - 1.1e-81 274.1 0.0 1.2e-81 273.9 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 KFP04211.1 - 0.051 13.8 0.0 1.2 9.6 0.0 3.0 2 1 0 2 2 2 0 Two component regulator propeller Kelch_6 PF13964.6 KFP04211.1 - 0.22 11.9 3.5 30 5.1 0.1 3.7 4 1 1 5 5 5 0 Kelch motif PI-PLC-X PF00388.19 KFP04212.1 - 0.0016 18.1 0.5 0.0049 16.5 0.4 1.8 1 1 1 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain GTP-bdg_M PF16360.5 KFP04213.1 - 1.6e-21 76.6 6.9 3.9e-21 75.4 6.9 1.7 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region GTP-bdg_N PF13167.6 KFP04213.1 - 6.8e-14 52.3 0.5 3.9e-13 49.9 0.1 2.3 2 0 0 2 2 2 1 GTP-binding GTPase N-terminal MMR_HSR1 PF01926.23 KFP04213.1 - 1.2e-12 47.9 0.0 3.4e-12 46.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Rad17 PF03215.15 KFP04213.1 - 0.002 18.1 0.2 0.43 10.5 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 KFP04213.1 - 0.0043 17.0 0.0 4.5 7.2 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 KFP04213.1 - 0.0056 16.4 0.1 0.1 12.3 0.0 2.7 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 KFP04213.1 - 0.0076 15.8 1.1 0.039 13.5 1.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KFP04213.1 - 0.022 15.1 0.0 0.059 13.7 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KFP04213.1 - 0.035 14.6 0.4 0.14 12.7 0.1 2.0 2 1 0 2 2 2 0 ABC transporter GTP_EFTU PF00009.27 KFP04213.1 - 0.056 13.0 0.1 4.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MobB PF03205.14 KFP04213.1 - 0.065 13.1 0.3 0.28 11.1 0.0 2.3 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1_Xtn PF16897.5 KFP04213.1 - 0.086 12.9 0.0 0.33 11.0 0.0 1.9 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain MnmE_helical PF12631.7 KFP04213.1 - 0.087 13.0 0.0 0.19 11.9 0.0 1.4 1 1 0 1 1 1 0 MnmE helical domain STAG PF08514.11 KFP04214.1 - 2.6e-33 114.3 0.1 2.6e-33 114.3 0.1 2.3 2 0 0 2 2 2 1 STAG domain DUF4020 PF13212.6 KFP04214.1 - 0.0079 16.0 0.7 0.7 9.7 0.0 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4020) HEAT PF02985.22 KFP04214.1 - 0.069 13.4 0.0 46 4.7 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat AHSP PF09236.10 KFP04214.1 - 0.27 11.7 5.5 1.9 9.0 0.1 3.5 3 0 0 3 3 3 0 Alpha-haemoglobin stabilising protein EF-hand_13 PF17958.1 KFP04215.1 - 5.4e-43 144.7 0.0 3.6e-41 138.9 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KFP04215.1 - 3.1e-26 91.6 9.8 6.3e-18 65.0 0.8 4.1 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP04215.1 - 4.2e-12 45.0 0.0 0.00037 19.9 0.0 4.1 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 KFP04215.1 - 4.2e-10 38.7 2.7 0.036 14.0 0.0 5.3 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 KFP04215.1 - 2.6e-09 36.0 1.8 0.064 12.8 0.1 5.5 6 0 0 6 6 6 2 EF hand EF-hand_8 PF13833.6 KFP04215.1 - 4.3e-08 32.9 0.5 0.55 10.1 0.0 5.6 6 0 0 6 6 6 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFP04215.1 - 0.00057 20.2 8.3 0.018 15.4 0.3 3.6 1 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Yae1_N PF09811.9 KFP04216.1 - 1e-17 63.5 63.9 1.8e+04 -28.7 63.9 6.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Homeodomain PF00046.29 KFP04217.1 - 6.5e-25 86.7 2.9 1.2e-24 85.9 2.9 1.5 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 KFP04217.1 - 1.8e-07 30.7 2.4 5.9e-07 29.1 2.4 1.9 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 KFP04217.1 - 0.0002 21.2 0.3 0.0011 18.8 0.0 2.3 2 0 0 2 2 2 1 Homeobox KN domain MRP-L20 PF12824.7 KFP04217.1 - 0.0074 16.5 0.5 0.019 15.2 0.5 1.7 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 CCDC53 PF10152.9 KFP04217.1 - 0.13 12.6 2.8 0.061 13.7 0.4 1.9 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex IL6Ra-bind PF09240.10 KFP04218.1 - 5e-22 78.1 2.1 5e-22 78.1 2.1 1.5 2 0 0 2 2 2 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.10 KFP04218.1 - 0.95 9.7 7.7 0.14 12.3 3.0 1.9 2 0 0 2 2 2 0 Erythropoietin receptor, ligand binding Mito_carr PF00153.27 KFP04219.1 - 8.6e-56 185.9 2.5 2.8e-23 81.7 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Methyltransf_2 PF00891.18 KFP04220.1 - 6.2e-54 182.5 0.0 1.1e-53 181.6 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Maf PF02545.14 KFP04220.1 - 1.9e-43 148.2 0.0 3.3e-43 147.4 0.0 1.4 1 0 0 1 1 1 1 Maf-like protein Dimerisation2 PF16864.5 KFP04220.1 - 2e-32 111.0 0.2 6.7e-32 109.3 0.2 1.9 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_23 PF13489.6 KFP04220.1 - 2.8e-06 27.3 0.0 5.7e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP04220.1 - 1.8e-05 25.3 0.0 7.3e-05 23.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP04220.1 - 7.6e-05 23.4 0.0 0.00021 22.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain 7tm_1 PF00001.21 KFP04221.1 - 4.9e-43 147.4 26.6 6.3e-43 147.0 26.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFP04221.1 - 0.0076 15.6 25.0 0.01 15.2 25.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv VHS PF00790.19 KFP04221.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 VHS domain DUF2254 PF10011.9 KFP04221.1 - 0.23 10.2 1.4 0.58 8.9 1.4 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) ANF_receptor PF01094.28 KFP04222.1 - 1.7e-24 86.6 0.1 2.1e-24 86.3 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region DUF4690 PF15756.5 KFP04222.1 - 0.075 13.6 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 Small Novel Rich in Cartilage PC4 PF02229.16 KFP04223.1 - 1.3e-25 88.7 0.4 2.1e-25 88.1 0.4 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) QLQ PF08880.11 KFP04223.1 - 0.024 14.4 0.2 0.035 13.9 0.2 1.2 1 0 0 1 1 1 0 QLQ RNA_pol_Rpc4 PF05132.14 KFP04223.1 - 0.047 14.1 3.4 0.051 14.0 3.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DZF PF07528.14 KFP04224.1 - 2.4e-65 220.6 0.0 3.8e-65 220.0 0.0 1.3 1 0 0 1 1 1 1 DZF domain zf-met PF12874.7 KFP04224.1 - 1e-21 76.6 15.3 1.8e-06 28.2 2.2 3.6 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP04224.1 - 8e-14 51.5 18.5 0.00026 21.2 2.4 4.3 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFP04224.1 - 0.0073 16.6 17.2 1.1 9.6 0.4 4.1 3 1 1 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.12 KFP04224.1 - 0.12 12.2 18.3 0.38 10.6 2.6 3.6 3 0 0 3 3 3 0 U1 zinc finger zf-C2H2_4 PF13894.6 KFP04224.1 - 1.8 9.6 10.7 14 6.8 1.5 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP04224.1 - 6.3 7.5 15.5 5.6 7.6 0.1 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type GPP34 PF05719.11 KFP04225.1 - 1e-53 182.5 0.3 1.2e-53 182.2 0.3 1.0 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Peptidase_M15_2 PF05951.13 KFP04225.1 - 0.16 11.6 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) PDZ PF00595.24 KFP04227.1 - 3e-52 174.9 6.1 1.6e-20 73.3 0.5 4.6 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 KFP04227.1 - 5.2e-31 106.3 1.9 1.4e-08 34.4 0.0 4.5 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 KFP04227.1 - 4.9e-17 62.0 0.4 0.0013 19.0 0.0 5.6 5 1 0 5 5 5 4 PDZ domain Collagen PF01391.18 KFP04228.1 - 1.7e-14 53.3 48.4 7.5e-08 32.0 26.3 2.4 2 0 0 2 2 2 2 Collagen triple helix repeat (20 copies) cEGF PF12662.7 KFP04228.1 - 3.5e-10 39.6 9.3 2.4e-05 24.1 1.5 3.0 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF_CA PF07645.15 KFP04228.1 - 1.8e-09 37.6 8.8 1.8e-09 37.6 8.8 3.0 3 1 0 3 3 3 1 Calcium-binding EGF domain FXa_inhibition PF14670.6 KFP04228.1 - 4.5e-09 36.4 29.2 4.9e-09 36.3 8.5 2.8 3 0 0 3 3 3 2 Coagulation Factor Xa inhibitory site EGF PF00008.27 KFP04228.1 - 3.2e-05 24.1 18.0 0.0011 19.2 4.5 2.9 2 0 0 2 2 2 2 EGF-like domain EGF_3 PF12947.7 KFP04228.1 - 0.0074 16.5 22.0 0.18 12.0 4.6 2.9 2 0 0 2 2 2 2 EGF domain hEGF PF12661.7 KFP04228.1 - 0.012 16.3 3.9 0.012 16.3 3.9 4.2 5 1 0 5 5 5 0 Human growth factor-like EGF Tme5_EGF_like PF09064.10 KFP04228.1 - 0.036 14.0 5.3 0.036 14.0 5.3 2.8 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like RhoGEF PF00621.20 KFP04229.1 - 1.2e-32 113.6 1.8 1.8e-32 113.0 1.8 1.3 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 KFP04229.1 - 3.2e-05 24.4 0.0 6.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 PH domain Myosin_head PF00063.21 KFP04230.1 - 1.7e-154 515.7 0.0 3.4e-154 514.7 0.0 1.5 1 1 0 1 1 1 1 Myosin head (motor domain) ER-remodelling PF14755.6 KFP04231.1 - 2.3e-05 24.7 6.2 2.5e-05 24.6 6.2 1.1 1 0 0 1 1 1 1 Intracellular membrane remodeller SH2 PF00017.24 KFP04232.1 - 0.0027 17.7 0.0 0.0031 17.6 0.0 1.1 1 0 0 1 1 1 1 SH2 domain Auxin_inducible PF02519.14 KFP04232.1 - 0.031 14.5 0.1 0.035 14.3 0.1 1.0 1 0 0 1 1 1 0 Auxin responsive protein Trm56 PF01994.16 KFP04232.1 - 0.16 11.9 0.0 0.18 11.7 0.0 1.0 1 0 0 1 1 1 0 tRNA ribose 2'-O-methyltransferase, aTrm56 Carb_anhydrase PF00194.21 KFP04233.1 - 1.6e-61 208.1 0.1 5e-33 114.7 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase Aph-1 PF06105.12 KFP04234.1 - 4e-85 284.9 12.0 4.5e-85 284.7 12.0 1.0 1 0 0 1 1 1 1 Aph-1 protein YqfD PF06898.11 KFP04234.1 - 0.0066 15.3 0.4 0.01 14.7 0.4 1.2 1 0 0 1 1 1 1 Putative stage IV sporulation protein YqfD OST3_OST6 PF04756.13 KFP04234.1 - 0.11 11.8 4.8 0.054 12.8 1.1 2.0 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Tropomyosin PF00261.20 KFP04235.1 - 6.2e-88 294.2 74.8 7.2e-82 274.3 46.6 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 KFP04235.1 - 9.4e-34 116.6 71.1 6.3e-29 101.0 42.1 3.3 1 1 0 2 2 2 2 Tropomyosin like CLZ PF16526.5 KFP04235.1 - 4.2e-05 23.8 46.2 5.2e-05 23.5 11.6 5.1 3 1 1 5 5 5 3 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Laminin_II PF06009.12 KFP04235.1 - 0.0001 22.3 33.7 0.00038 20.5 4.9 3.9 1 1 3 4 4 4 3 Laminin Domain II YscO PF07321.12 KFP04235.1 - 0.0045 17.0 2.4 0.0045 17.0 2.4 4.6 1 1 4 5 5 5 1 Type III secretion protein YscO MscS_porin PF12795.7 KFP04235.1 - 0.01 15.4 40.6 0.12 11.9 21.6 2.7 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain SlyX PF04102.12 KFP04235.1 - 0.015 15.9 0.4 0.015 15.9 0.4 5.6 1 1 5 6 6 6 0 SlyX TMF_DNA_bd PF12329.8 KFP04235.1 - 0.025 14.6 8.9 0.025 14.6 8.9 5.9 2 2 2 5 5 5 0 TATA element modulatory factor 1 DNA binding ERM PF00769.19 KFP04235.1 - 0.055 13.3 71.4 0.17 11.7 11.6 2.8 1 1 2 3 3 3 0 Ezrin/radixin/moesin family DUF16 PF01519.16 KFP04235.1 - 0.073 13.6 0.6 0.073 13.6 0.6 4.2 1 1 3 4 4 4 0 Protein of unknown function DUF16 Laminin_I PF06008.14 KFP04235.1 - 0.073 12.8 47.0 0.5 10.0 13.6 3.1 1 1 2 3 3 3 0 Laminin Domain I CENP-F_leu_zip PF10473.9 KFP04235.1 - 0.14 12.2 64.6 0.018 15.0 27.3 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HrpB7 PF09486.10 KFP04235.1 - 0.4 11.1 45.9 3.3 8.1 5.9 4.8 1 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) SNARE PF05739.19 KFP04235.1 - 1.1 9.3 12.7 3 7.9 0.1 4.0 4 0 0 4 4 4 0 SNARE domain DUF4164 PF13747.6 KFP04235.1 - 1.3 9.4 51.9 0.034 14.4 11.0 4.5 2 1 3 5 5 5 0 Domain of unknown function (DUF4164) HOOK PF05622.12 KFP04235.1 - 1.7 6.7 56.5 0.01 14.1 11.4 2.2 1 1 1 2 2 2 0 HOOK protein Lebercilin PF15619.6 KFP04235.1 - 2 8.0 62.5 0.22 11.2 12.3 3.2 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Exonuc_VII_L PF02601.15 KFP04235.1 - 2.1 7.9 34.3 4.5 6.7 17.5 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit Fib_alpha PF08702.10 KFP04235.1 - 2.1 8.5 31.8 0.18 12.0 5.2 3.3 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family ATG16 PF08614.11 KFP04235.1 - 3.2 7.9 56.4 0.62 10.3 7.4 3.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) XhlA PF10779.9 KFP04235.1 - 6.6 7.0 52.3 0.23 11.7 1.3 6.6 2 2 5 7 7 7 0 Haemolysin XhlA Spectrin PF00435.21 KFP04235.1 - 7.5 7.1 43.7 0.16 12.5 3.5 4.6 1 1 3 4 4 4 0 Spectrin repeat DUF745 PF05335.13 KFP04235.1 - 8.4 6.1 46.6 2.8 7.6 5.8 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF745) DUF948 PF06103.11 KFP04235.1 - 8.7 6.7 16.5 4.3 7.7 1.4 4.1 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) TPR_MLP1_2 PF07926.12 KFP04235.1 - 8.8 6.4 69.8 1 9.4 15.4 4.3 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein Avidin PF01382.17 KFP04236.1 - 8.7e-32 110.0 1.9 9.6e-32 109.9 1.9 1.0 1 0 0 1 1 1 1 Avidin family Avidin PF01382.17 KFP04237.1 - 1.4e-37 128.6 2.7 1.6e-37 128.5 2.7 1.0 1 0 0 1 1 1 1 Avidin family Avidin PF01382.17 KFP04238.1 - 9.2e-38 129.3 3.5 1e-37 129.1 3.5 1.0 1 0 0 1 1 1 1 Avidin family Big_1 PF02369.16 KFP04238.1 - 0.09 12.8 0.6 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) DUF608 PF04685.13 KFP04239.1 - 2.4e-171 569.8 6.6 3.2e-171 569.4 6.6 1.2 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Glyco_hydr_116N PF12215.8 KFP04239.1 - 4.7e-107 358.1 0.0 6.9e-107 357.5 0.0 1.3 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Bac_rhamnosid6H PF17389.2 KFP04239.1 - 0.0022 17.3 1.3 0.004 16.5 1.3 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain GDE_C PF06202.14 KFP04239.1 - 0.023 13.6 0.2 0.037 13.0 0.2 1.2 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase DUF5127 PF17168.4 KFP04239.1 - 0.024 14.4 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5127) Glyco_hydro_36 PF17167.4 KFP04239.1 - 0.032 12.9 0.4 0.057 12.1 0.4 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain Rgp1 PF08737.10 KFP04240.1 - 8.5e-34 117.4 0.7 7.7e-25 87.9 0.0 2.5 2 1 1 3 3 3 2 Rgp1 PSP94 PF05825.11 KFP04241.1 - 7.4e-08 32.9 5.0 9.7e-08 32.5 5.0 1.1 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) ANF_receptor PF01094.28 KFP04242.1 - 4e-15 55.8 0.1 4.5e-15 55.6 0.1 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Guanylate_cyc PF00211.20 KFP04243.1 - 2.4e-39 134.8 0.1 1.7e-37 128.9 0.0 2.1 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KFP04243.1 - 2e-05 24.2 0.6 2.7e-05 23.7 0.6 1.2 1 0 0 1 1 1 1 Heme NO binding associated Pkinase_Tyr PF07714.17 KFP04243.1 - 0.00041 19.7 0.0 0.00084 18.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase dsDNA_bind PF01984.20 KFP04243.1 - 0.029 14.6 0.0 0.053 13.8 0.0 1.4 1 0 0 1 1 1 0 Double-stranded DNA-binding domain Fe_bilin_red PF05996.12 KFP04243.1 - 0.085 12.5 0.3 7.3 6.2 0.2 2.1 1 1 1 2 2 2 0 Ferredoxin-dependent bilin reductase HIT PF01230.23 KFP04244.1 - 1.5e-21 76.9 0.1 1.7e-21 76.8 0.1 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KFP04244.1 - 4e-15 56.3 0.0 4.6e-15 56.1 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF3522 PF12036.8 KFP04246.1 - 3e-09 37.4 4.3 4.9e-09 36.7 4.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) Plasmod_Pvs28 PF06247.11 KFP04246.1 - 0.64 10.4 5.6 1.9 8.8 5.6 1.8 1 0 0 1 1 1 0 Pvs28 EGF domain EGF_2 PF07974.13 KFP04246.1 - 4.3 7.8 8.5 16 5.9 8.5 2.1 1 0 0 1 1 1 0 EGF-like domain Lectin_C PF00059.21 KFP04248.1 - 2.1e-06 28.4 3.8 5.9e-06 27.0 3.8 1.8 1 1 0 1 1 1 1 Lectin C-type domain CENP-F_leu_zip PF10473.9 KFP04248.1 - 0.0013 18.8 1.1 0.0019 18.2 1.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HemX PF04375.14 KFP04248.1 - 0.013 14.8 0.3 0.018 14.4 0.3 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase APG6_N PF17675.1 KFP04248.1 - 0.016 15.7 1.6 0.028 14.9 1.6 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Spc7 PF08317.11 KFP04248.1 - 0.025 13.5 0.9 0.036 12.9 0.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein MscS_porin PF12795.7 KFP04248.1 - 0.093 12.3 7.8 0.2 11.2 7.8 1.4 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain HMMR_N PF15905.5 KFP04248.1 - 0.11 11.9 0.1 0.15 11.5 0.1 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF1664 PF07889.12 KFP04248.1 - 0.17 11.9 0.1 0.43 10.6 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 KFP04248.1 - 0.21 11.8 7.3 0.31 11.2 7.3 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Pkinase_Tyr PF07714.17 KFP04249.1 - 9.4e-46 156.2 0.0 1.1e-45 155.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP04249.1 - 5.2e-41 140.7 0.0 8e-41 140.1 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KFP04249.1 - 0.00023 20.6 0.0 0.00038 19.9 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFP04249.1 - 0.00031 19.7 0.0 0.00044 19.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP04249.1 - 0.012 15.5 0.0 0.93 9.4 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Y_phosphatase PF00102.27 KFP04250.1 - 1.6e-15 57.4 0.1 1.7e-15 57.3 0.1 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFP04250.1 - 1.2e-05 25.2 0.1 1.5e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP04251.1 - 1.4e-102 342.3 0.0 1.4e-83 280.1 0.0 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 KFP04251.1 - 5.9e-06 26.1 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP04251.1 - 0.0031 17.5 0.0 0.0057 16.6 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFP04251.1 - 0.046 13.8 0.1 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate PhoLip_ATPase_C PF16212.5 KFP04252.1 - 1e-82 277.7 29.2 1e-82 277.7 29.2 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFP04252.1 - 3.7e-26 90.6 9.7 9.8e-26 89.2 9.7 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFP04252.1 - 4.2e-12 46.8 0.1 2e-05 25.0 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFP04252.1 - 6.7e-11 42.1 0.0 1.9e-09 37.4 0.0 2.7 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFP04252.1 - 4.2e-06 26.4 0.0 1.4e-05 24.7 0.0 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFP04252.1 - 0.00035 20.4 0.0 0.0013 18.5 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFP04252.1 - 0.022 14.9 2.1 2.4 8.2 0.0 2.9 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase C2 PF00168.30 KFP04253.1 - 3.6e-09 36.8 0.1 4.6e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 C2 domain Chromosome_seg PF13889.6 KFP04255.1 - 1.3e-16 60.4 0.3 3e-16 59.3 0.1 1.8 2 0 0 2 2 2 1 Chromosome segregation during meiosis DUF4210 PF13915.6 KFP04255.1 - 2.3e-14 53.7 0.0 4.1e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Band_7 PF01145.25 KFP04256.1 - 2.4e-31 109.1 0.2 2.4e-31 109.1 0.2 2.0 1 1 1 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KFP04256.1 - 3.2e-18 65.5 0.7 9.5e-18 64.0 0.7 1.9 1 0 0 1 1 1 1 C-terminal region of band_7 DUF4769 PF15992.5 KFP04256.1 - 0.021 14.7 0.4 0.031 14.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) Band_7_1 PF13421.6 KFP04256.1 - 0.077 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Phosphodiest PF01663.22 KFP04257.1 - 8.1e-13 48.7 0.5 1.2e-12 48.1 0.1 1.4 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KFP04257.1 - 0.00033 20.1 0.0 0.00065 19.1 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily PglZ PF08665.12 KFP04257.1 - 0.018 15.1 2.5 1.2 9.2 0.0 3.0 3 0 0 3 3 3 0 PglZ domain TPR_2 PF07719.17 KFP04258.1 - 5.3e-18 63.6 5.9 0.0039 17.2 0.0 7.3 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 KFP04258.1 - 1.3e-14 53.3 7.1 5.2e-05 22.9 0.0 6.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP04258.1 - 1.8e-10 40.7 16.3 0.0093 16.7 0.0 7.3 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFP04258.1 - 3.1e-10 40.4 11.7 0.0072 16.8 0.1 5.5 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFP04258.1 - 3.1e-09 37.0 12.9 0.00094 19.4 0.1 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP04258.1 - 7.5e-08 32.0 0.0 5.2 7.5 0.0 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFP04258.1 - 3.1e-07 30.9 14.7 5 7.9 0.1 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFP04258.1 - 2.3e-05 24.1 10.0 0.88 9.7 0.0 6.3 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 KFP04258.1 - 3.7e-05 23.1 0.5 0.068 12.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFP04258.1 - 0.00012 21.7 1.1 0.27 10.9 0.0 4.5 5 0 0 5 5 4 1 TPR repeat ANAPC3 PF12895.7 KFP04258.1 - 0.00069 19.8 7.5 3.3 8.0 1.8 4.9 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KFP04258.1 - 0.0007 19.4 12.2 5.6 7.0 0.0 6.4 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFP04258.1 - 0.0017 18.9 5.9 18 6.2 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 KFP04258.1 - 0.0071 16.7 5.1 5.5 7.4 0.1 5.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 KFP04258.1 - 0.0093 16.5 13.8 16 6.5 0.1 6.2 6 1 0 6 6 6 0 Tetratricopeptide repeat BTAD PF03704.17 KFP04258.1 - 0.021 15.3 7.5 0.14 12.6 0.0 4.2 4 2 1 5 5 5 0 Bacterial transcriptional activator domain TPR_9 PF13371.6 KFP04258.1 - 0.025 14.7 2.0 12 6.1 0.1 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat DnaJ_C PF01556.18 KFP04259.1 - 2.1e-45 154.4 0.1 2.8e-45 154.0 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFP04259.1 - 3.8e-29 100.6 4.3 6e-29 100.0 4.3 1.3 1 0 0 1 1 1 1 DnaJ domain Zf_RING PF16744.5 KFP04260.1 - 2e-37 127.1 8.5 4.2e-37 126.1 8.5 1.5 1 0 0 1 1 1 1 KIAA1045 RING finger EF-hand_1 PF00036.32 KFP04260.1 - 2.9e-07 29.6 0.2 0.013 15.0 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFP04260.1 - 1.5e-06 27.7 0.2 0.0083 16.0 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KFP04260.1 - 3.6e-06 27.3 0.5 0.035 14.5 0.1 2.9 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFP04260.1 - 2.5e-05 24.0 0.0 0.065 13.1 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair Zn_ribbon_17 PF17120.5 KFP04260.1 - 0.00071 19.2 2.7 0.00071 19.2 2.7 2.1 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type EF-hand_5 PF13202.6 KFP04260.1 - 0.014 14.9 1.4 1.4 8.5 0.1 2.9 3 0 0 3 3 3 0 EF hand DUF3673 PF12425.8 KFP04260.1 - 0.089 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3673) PHD_4 PF16866.5 KFP04260.1 - 0.97 9.6 8.4 0.55 10.4 5.4 2.3 1 1 1 2 2 2 0 PHD-finger PHD PF00628.29 KFP04260.1 - 9.7 6.2 16.6 0.33 10.9 10.0 2.1 2 1 0 2 2 2 0 PHD-finger IL8 PF00048.20 KFP04261.1 - 1.8e-19 69.7 0.1 2e-19 69.5 0.1 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Ig_3 PF13927.6 KFP04262.1 - 0.0019 18.8 0.2 0.01 16.4 0.0 2.2 2 1 0 2 2 2 1 Immunoglobulin domain IL12p40_C PF10420.9 KFP04262.1 - 0.0034 17.9 0.1 0.0069 16.9 0.1 1.4 1 0 0 1 1 1 1 Cytokine interleukin-12p40 C-terminus ISK_Channel PF02060.15 KFP04262.1 - 0.0065 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Slow voltage-gated potassium channel EpoR_lig-bind PF09067.10 KFP04262.1 - 0.0072 16.5 0.2 0.012 15.8 0.2 1.4 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding TMEM154 PF15102.6 KFP04262.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Stevor PF17410.2 KFP04262.1 - 0.042 13.4 0.0 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF2207 PF09972.9 KFP04262.1 - 0.059 12.1 0.0 0.084 11.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) fn3 PF00041.21 KFP04263.1 - 3.3e-07 30.6 1.1 7.7e-07 29.4 0.2 2.2 2 0 0 2 2 2 1 Fibronectin type III domain Ig_5 PF16681.5 KFP04263.1 - 2.7e-05 24.5 0.1 5.9e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_2 PF13895.6 KFP04263.1 - 0.00018 21.8 0.2 0.00052 20.3 0.2 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFP04263.1 - 0.00019 22.0 0.2 0.00019 22.0 0.2 2.7 3 0 0 3 3 3 1 Immunoglobulin domain Ig_4 PF16680.5 KFP04263.1 - 0.0024 18.1 0.1 0.0052 17.0 0.1 1.6 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 delta chain I-set PF07679.16 KFP04263.1 - 0.023 14.7 0.4 0.3 11.2 0.1 2.7 2 0 0 2 2 2 0 Immunoglobulin I-set domain IL12p40_C PF10420.9 KFP04263.1 - 0.024 15.1 0.1 0.082 13.4 0.1 1.9 1 0 0 1 1 1 0 Cytokine interleukin-12p40 C-terminus DUF5124 PF17160.4 KFP04263.1 - 0.053 14.3 0.2 0.092 13.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5124) ig PF00047.25 KFP04263.1 - 0.083 13.1 0.5 0.64 10.2 0.2 2.4 2 0 0 2 2 2 0 Immunoglobulin domain CysA_C_terminal PF17850.1 KFP04264.1 - 0.12 12.9 5.2 1.2e+02 3.4 5.2 3.5 1 1 0 1 1 1 0 CysA C-terminal regulatory domain GalP_UDP_transf PF01087.22 KFP04265.1 - 2.4e-63 213.9 0.1 3.2e-63 213.5 0.1 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KFP04265.1 - 1.1e-32 113.1 0.1 2.3e-32 112.0 0.1 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4931 PF16285.5 KFP04265.1 - 0.00061 19.2 0.0 0.00089 18.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4931) HIT PF01230.23 KFP04265.1 - 0.0047 17.6 0.0 0.021 15.6 0.0 1.9 2 0 0 2 2 2 1 HIT domain Tropomodulin PF03250.14 KFP04265.1 - 0.07 13.2 0.0 0.43 10.6 0.0 2.0 2 0 0 2 2 2 0 Tropomodulin ERG2_Sigma1R PF04622.12 KFP04266.1 - 1.8e-64 216.9 0.4 2.1e-64 216.7 0.4 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein ARID PF01388.21 KFP04267.1 - 9.1e-18 64.7 0.0 2.2e-17 63.5 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain ketoacyl-synt PF00109.26 KFP04267.1 - 0.0092 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PSP1 PF04468.12 KFP04267.1 - 0.1 12.9 0.1 5.9 7.2 0.0 2.7 2 1 1 3 3 3 0 PSP1 C-terminal conserved region Dynactin_p22 PF07426.11 KFP04268.1 - 4.4e-37 127.5 4.1 5.1e-37 127.3 4.1 1.0 1 0 0 1 1 1 1 Dynactin subunit p22 Myb_DNA-bind_3 PF12776.7 KFP04268.1 - 0.013 16.5 0.1 0.016 16.2 0.1 1.2 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Alba PF01918.21 KFP04269.1 - 4.7e-16 58.4 0.9 6.4e-16 57.9 0.9 1.2 1 0 0 1 1 1 1 Alba WD40 PF00400.32 KFP04270.1 - 3.3e-09 37.2 14.6 0.0064 17.3 2.8 6.4 6 1 1 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP04270.1 - 4.6e-07 30.0 0.5 0.1 12.9 0.0 4.8 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain ELYS-bb PF16687.5 KFP04270.1 - 0.054 12.1 0.0 0.08 11.5 0.0 1.2 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin FAM219A PF15260.6 KFP04271.1 - 3.3e-48 163.2 2.6 4.1e-48 162.9 2.6 1.1 1 0 0 1 1 1 1 Protein family FAM219A SMRP1 PF15181.6 KFP04272.1 - 3.1e-56 190.9 4.3 3.8e-56 190.6 4.3 1.0 1 0 0 1 1 1 1 Spermatid-specific manchette-related protein 1 Glyco_hydro_31 PF01055.26 KFP04273.1 - 2.5e-58 198.3 1.7 2.1e-34 119.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 Melibiase PF02065.18 KFP04273.1 - 0.0049 15.9 0.1 0.0099 14.9 0.1 1.5 1 0 0 1 1 1 1 Melibiase Glyco_hydro_31 PF01055.26 KFP04275.1 - 1.8e-59 202.1 1.8 2.2e-34 119.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 Melibiase PF02065.18 KFP04275.1 - 0.0033 16.4 0.1 0.0062 15.5 0.1 1.4 1 0 0 1 1 1 1 Melibiase DPM2 PF07297.12 KFP04275.1 - 1.3 9.3 3.1 53 4.2 0.0 2.7 2 0 0 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Ricin_B_lectin PF00652.22 KFP04277.1 - 2.5e-11 43.9 4.5 4.7e-11 43.0 4.3 1.5 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain NUDIX PF00293.28 KFP04278.1 - 4.9e-20 71.9 0.1 5.8e-20 71.7 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain I-set PF07679.16 KFP04278.1 - 0.078 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain Kinesin PF00225.23 KFP04279.1 - 2.5e-51 174.6 1.7 5.5e-51 173.4 1.7 1.6 1 0 0 1 1 1 1 Kinesin motor domain SAM_1 PF00536.30 KFP04279.1 - 0.0028 18.1 0.1 0.0066 16.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP04279.1 - 0.023 14.8 0.1 0.048 13.8 0.1 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) UBA PF00627.31 KFP04280.1 - 2.1e-06 27.5 0.6 0.00014 21.6 0.0 3.4 4 0 0 4 4 4 1 UBA/TS-N domain UBA_3 PF09288.10 KFP04280.1 - 0.002 17.9 0.8 0.46 10.3 0.0 3.0 3 0 0 3 3 3 2 Fungal ubiquitin-associated domain MerR-DNA-bind PF09278.11 KFP04280.1 - 0.067 13.7 0.1 0.22 12.1 0.1 2.0 1 0 0 1 1 1 0 MerR, DNA binding DUF1421 PF07223.11 KFP04280.1 - 0.11 12.3 0.0 0.33 10.8 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain (DUF1421) DUF2203 PF09969.9 KFP04280.1 - 0.34 11.6 2.3 0.93 10.2 0.1 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) WD40 PF00400.32 KFP04281.1 - 8.7e-05 23.2 1.7 1 10.4 1.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat WD40_like PF17005.5 KFP04281.1 - 0.00023 20.6 0.0 0.34 10.2 0.0 2.4 3 0 0 3 3 3 2 WD40-like domain ANAPC4_WD40 PF12894.7 KFP04281.1 - 0.01 16.1 0.0 8.8 6.7 0.0 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain CNH PF00780.22 KFP04281.1 - 0.087 12.4 0.0 4.5 6.8 0.0 2.1 2 0 0 2 2 2 0 CNH domain Interferon PF00143.19 KFP04282.1 - 3.7e-32 111.7 0.1 4.3e-32 111.5 0.1 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain UQ_con PF00179.26 KFP04283.1 - 6.9e-30 103.5 0.3 8.7e-30 103.2 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Nrap_D4 PF17405.2 KFP04284.1 - 2.1e-55 187.4 0.0 3.9e-55 186.5 0.0 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 KFP04284.1 - 4.2e-52 176.2 0.6 4.3e-50 169.6 0.1 2.6 3 0 0 3 3 3 1 Nrap protein PAP/OAS1-like domain 5 Nrap PF03813.14 KFP04284.1 - 3.7e-49 166.7 0.0 1.1e-48 165.1 0.0 1.8 2 0 0 2 2 2 1 Nrap protein domain 1 Nrap_D2 PF17403.2 KFP04284.1 - 3.3e-44 150.3 0.9 1.8e-41 141.4 0.1 2.4 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap_D3 PF17404.2 KFP04284.1 - 1e-40 139.4 0.0 1.8e-40 138.6 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 KFP04284.1 - 7.9e-33 113.5 0.0 1.6e-32 112.5 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 6 MIP PF00230.20 KFP04285.1 - 2.8e-51 174.4 13.5 3.4e-51 174.1 13.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein CPP1-like PF11833.8 KFP04285.1 - 9.9 5.8 6.8 44 3.6 0.0 2.8 3 1 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like MIP PF00230.20 KFP04286.1 - 1.3e-44 152.6 10.1 1.6e-44 152.3 10.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF3172 PF11371.8 KFP04286.1 - 0.051 13.3 1.1 0.066 12.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3172) aGPT-Pplase1 PF18723.1 KFP04286.1 - 0.19 11.2 0.2 0.29 10.5 0.2 1.2 1 0 0 1 1 1 0 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 SMI1_KNR4 PF09346.10 KFP04287.1 - 0.0098 16.3 0.0 0.016 15.6 0.0 1.4 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) RRM_1 PF00076.22 KFP04288.1 - 2.7e-37 126.4 0.0 1.5e-17 63.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP04288.1 - 0.00038 20.0 0.0 0.26 10.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFP04288.1 - 0.0036 17.3 0.0 0.14 12.1 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.11 KFP04288.1 - 0.012 15.6 0.0 1.8 8.6 0.0 3.0 2 1 0 2 2 2 0 RNA binding domain RRM_3 PF08777.11 KFP04288.1 - 0.024 14.7 0.0 5.6 7.1 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif RRM_7 PF16367.5 KFP04288.1 - 0.03 14.4 0.0 11 6.2 0.0 2.8 2 1 0 2 2 2 0 RNA recognition motif PHM7_cyt PF14703.6 KFP04288.1 - 0.25 11.5 1.0 17 5.6 0.1 2.9 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter TF_Otx PF03529.13 KFP04288.1 - 0.37 11.2 15.0 0.26 11.7 3.6 2.5 2 0 0 2 2 2 0 Otx1 transcription factor RRM_1 PF00076.22 KFP04289.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RVT_1 PF00078.27 KFP04290.1 - 0.055 13.0 0.1 0.18 11.3 0.0 1.9 3 0 0 3 3 3 0 Reverse transcriptase (RNA-dependent DNA polymerase) Yae1_N PF09811.9 KFP04291.1 - 5.4e-11 42.0 30.9 32 4.3 30.9 3.3 1 1 0 1 1 1 1 Essential protein Yae1, N terminal PI3Ka PF00613.20 KFP04292.1 - 1.2e-57 194.3 1.8 2.5e-57 193.3 1.8 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KFP04292.1 - 3e-53 181.2 0.0 1.7e-49 168.9 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KFP04292.1 - 1.9e-49 167.2 0.0 3.5e-49 166.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 KFP04292.1 - 0.0051 16.2 0.0 0.014 14.8 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4135) HEAT_2 PF13646.6 KFP04292.1 - 0.0087 16.4 0.2 0.022 15.2 0.2 1.7 1 0 0 1 1 1 1 HEAT repeats Ras PF00071.22 KFP04294.1 - 1.8e-42 144.7 0.0 2.1e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP04294.1 - 6.1e-11 42.6 0.0 1e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP04294.1 - 5.2e-05 22.8 0.0 7.4e-05 22.3 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP04294.1 - 0.002 17.7 0.0 0.0024 17.5 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KFP04294.1 - 0.0082 15.9 0.0 0.0096 15.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein NADH_Oxid_Nqo15 PF11497.8 KFP04294.1 - 0.064 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 C2 PF00168.30 KFP04295.1 - 2.8e-44 149.6 0.0 4.9e-21 75.0 0.0 2.3 2 0 0 2 2 2 2 C2 domain PTEN_C2 PF10409.9 KFP04295.1 - 0.0059 16.4 0.1 0.018 14.8 0.0 1.9 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein CEP76-C2 PF15627.6 KFP04295.1 - 0.023 14.3 0.0 3 7.4 0.0 2.4 2 0 0 2 2 2 0 CEP76 C2 domain Glypican PF01153.19 KFP04296.1 - 8.3e-226 751.1 7.0 1e-225 750.9 7.0 1.0 1 0 0 1 1 1 1 Glypican DUF1910 PF08928.10 KFP04296.1 - 0.013 15.5 0.4 0.14 12.1 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) DUF5082 PF16888.5 KFP04296.1 - 0.046 14.0 0.3 0.34 11.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Sulfotransfer_2 PF03567.14 KFP04297.1 - 1e-11 45.3 0.1 1e-11 45.3 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase family SH3_9 PF14604.6 KFP04299.1 - 4.1e-11 42.6 0.0 8.1e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP04299.1 - 0.00013 21.5 0.0 0.00025 20.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain NodZ PF05830.11 KFP04299.1 - 0.018 13.9 0.4 0.04 12.7 0.0 1.7 2 0 0 2 2 2 0 Nodulation protein Z (NodZ) Wtap PF17098.5 KFP04299.1 - 0.07 13.1 1.0 1.5 8.7 0.2 2.3 2 0 0 2 2 2 0 WTAP/Mum2p family SKI PF01202.22 KFP04299.1 - 0.093 12.8 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase GrpE PF01025.19 KFP04299.1 - 0.17 11.5 0.5 0.36 10.5 0.5 1.6 1 0 0 1 1 1 0 GrpE C1q PF00386.21 KFP04300.1 - 1.4e-71 238.7 1.6 2.2e-38 131.3 0.1 2.1 2 0 0 2 2 2 2 C1q domain BclA_C PF18573.1 KFP04300.1 - 1.1e-06 28.6 0.0 0.041 13.8 0.0 2.1 2 0 0 2 2 2 2 BclA C-terminal domain Rhodanese PF00581.20 KFP04300.1 - 0.00067 20.1 0.0 0.65 10.5 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain DUF3531 PF12049.8 KFP04300.1 - 0.044 13.7 0.1 11 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3531) Complex1_30kDa PF00329.19 KFP04301.1 - 2.8e-43 147.4 0.0 3.6e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit BTB PF00651.31 KFP04302.1 - 5.9e-26 90.9 2.3 1.1e-25 90.0 2.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.6 KFP04302.1 - 9e-18 63.9 5.0 5.2e-06 26.5 0.0 5.3 3 2 2 5 5 5 3 Kelch motif BACK PF07707.15 KFP04302.1 - 9.8e-10 38.5 0.8 9.2e-08 32.1 0.1 2.5 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 KFP04302.1 - 3.7e-07 29.9 0.4 0.048 13.6 0.1 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 KFP04302.1 - 1.8e-06 27.4 1.0 0.026 14.1 0.0 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 KFP04302.1 - 0.00046 20.1 0.4 0.1 12.6 0.0 3.4 3 0 0 3 3 3 1 Galactose oxidase, central domain DSPc PF00782.20 KFP04303.1 - 2.1e-16 59.9 0.0 2.3e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP04303.1 - 2.7e-05 23.9 0.4 0.00023 20.8 0.3 1.9 1 1 1 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KFP04303.1 - 0.001 18.7 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPn PF14671.6 KFP04303.1 - 0.0016 18.9 0.0 0.0021 18.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half PTPlike_phytase PF14566.6 KFP04303.1 - 0.074 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate RRM_1 PF00076.22 KFP04304.1 - 1.5e-51 172.1 0.0 2.3e-18 65.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 KFP04304.1 - 7.2e-10 38.8 0.0 0.1 12.7 0.0 3.9 3 2 0 3 3 3 3 RNA binding domain RRM_7 PF16367.5 KFP04304.1 - 0.0002 21.4 0.0 0.75 10.0 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif PHM7_cyt PF14703.6 KFP04304.1 - 0.0036 17.5 5.9 4.2 7.6 1.4 4.3 3 2 1 4 4 4 2 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 KFP04304.1 - 0.016 15.2 0.0 0.56 10.3 0.0 2.9 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif AID PF18767.1 KFP04304.1 - 0.074 13.1 0.0 2.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Activation induced deaminase BRAP2 PF07576.12 KFP04304.1 - 0.084 13.1 0.1 4.3 7.6 0.0 2.8 3 0 0 3 3 3 0 BRCA1-associated protein 2 Rapsyn_N PF10579.9 KFP04305.1 - 1.6e-43 146.6 0.3 1.9e-42 143.3 0.1 2.5 2 0 0 2 2 2 1 Rapsyn N-terminal myristoylation and linker region TPR_1 PF00515.28 KFP04305.1 - 6.3e-21 73.3 13.1 0.00018 21.2 0.1 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 KFP04305.1 - 3.6e-20 72.0 3.5 9.7e-07 29.0 0.0 5.3 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 KFP04305.1 - 1.7e-15 55.8 11.6 0.0047 16.9 0.1 6.7 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFP04305.1 - 9.7e-12 44.1 8.7 0.038 14.2 0.1 6.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFP04305.1 - 3.8e-11 42.2 1.5 0.062 13.4 0.0 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP04305.1 - 4.9e-08 32.7 1.6 2.5e-06 27.1 0.2 2.8 2 1 1 3 3 3 1 MalT-like TPR region zf-RING_2 PF13639.6 KFP04305.1 - 8.4e-08 32.4 4.1 8.4e-08 32.4 4.1 3.8 4 0 0 4 4 4 1 Ring finger domain TPR_10 PF13374.6 KFP04305.1 - 2.2e-06 27.4 1.4 0.0014 18.5 0.2 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat zf-RING_11 PF17123.5 KFP04305.1 - 2.8e-06 27.0 2.5 2.8e-06 27.0 2.5 2.9 3 0 0 3 3 2 1 RING-like zinc finger DUF3856 PF12968.7 KFP04305.1 - 1.8e-05 24.8 1.9 0.4 10.7 0.0 3.9 3 1 1 4 4 4 2 Domain of Unknown Function (DUF3856) TPR_19 PF14559.6 KFP04305.1 - 9.3e-05 22.9 0.4 2.7 8.6 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFP04305.1 - 0.00014 21.4 0.5 6.7 6.5 0.0 4.9 5 0 0 5 5 5 0 TPR repeat SNAP PF14938.6 KFP04305.1 - 0.00051 19.6 0.2 0.76 9.1 0.2 2.3 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP zf-RING_5 PF14634.6 KFP04305.1 - 0.00062 19.7 6.1 0.00062 19.7 6.1 3.6 3 0 0 3 3 3 1 zinc-RING finger domain TPR_6 PF13174.6 KFP04305.1 - 0.0024 18.4 4.5 1.8 9.4 0.1 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFP04305.1 - 0.0039 17.9 2.4 3.1 8.9 0.1 4.9 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFP04305.1 - 0.0041 17.7 0.3 68 4.2 0.1 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat Prok-RING_4 PF14447.6 KFP04305.1 - 0.0094 15.8 4.4 0.0094 15.8 4.4 3.0 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 Fis1_TPR_C PF14853.6 KFP04305.1 - 0.01 15.9 4.3 0.41 10.8 0.0 4.2 5 0 0 5 5 3 0 Fis1 C-terminal tetratricopeptide repeat zf-C3HC4 PF00097.25 KFP04305.1 - 0.011 15.6 4.4 0.011 15.6 4.4 3.6 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) RPN7 PF10602.9 KFP04305.1 - 0.023 14.4 5.1 1.1 9.0 1.1 3.6 2 1 2 4 4 4 0 26S proteasome subunit RPN7 PCYCGC PF13798.6 KFP04305.1 - 0.034 14.0 1.9 0.092 12.6 0.6 2.4 3 0 0 3 3 3 0 Protein of unknown function with PCYCGC motif zf-rbx1 PF12678.7 KFP04305.1 - 0.055 13.8 7.0 0.27 11.6 7.0 2.3 1 0 0 1 1 1 0 RING-H2 zinc finger domain ANAPC5 PF12862.7 KFP04305.1 - 0.075 13.1 1.2 15 5.7 0.7 3.7 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 5 Cys_rich_CPXG PF14255.6 KFP04305.1 - 0.53 10.2 0.1 0.53 10.2 0.1 3.1 4 0 0 4 4 3 0 Cysteine-rich CPXCG ANAPC3 PF12895.7 KFP04305.1 - 0.91 9.8 9.5 7.4 6.9 0.6 3.7 3 1 1 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-RING_UBOX PF13445.6 KFP04305.1 - 2.5 8.2 12.8 1.6 8.8 5.7 3.2 3 0 0 3 3 2 0 RING-type zinc-finger TPR_17 PF13431.6 KFP04305.1 - 9.3 6.9 10.0 23 5.6 0.8 4.9 5 1 0 5 5 3 0 Tetratricopeptide repeat AAA PF00004.29 KFP04306.1 - 6.1e-42 143.2 0.0 1.4e-41 142.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KFP04306.1 - 5.3e-20 71.1 0.1 1.3e-19 69.9 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KFP04306.1 - 2.7e-10 39.9 1.1 4.5e-10 39.2 0.3 1.9 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 KFP04306.1 - 3.1e-06 27.2 0.4 2.3e-05 24.4 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFP04306.1 - 1.8e-05 25.2 0.2 0.004 17.6 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KFP04306.1 - 4e-05 23.4 0.0 0.00015 21.6 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KFP04306.1 - 0.00019 21.6 0.0 0.00082 19.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFP04306.1 - 0.00059 20.1 0.3 0.09 13.1 0.1 2.6 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFP04306.1 - 0.0032 17.6 0.1 0.0067 16.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KFP04306.1 - 0.0032 16.7 0.0 0.0062 15.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PhoH PF02562.16 KFP04306.1 - 0.0044 16.5 0.1 0.021 14.3 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 KFP04306.1 - 0.0057 16.0 0.1 0.017 14.5 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 KFP04306.1 - 0.008 16.0 0.2 0.54 10.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Prot_ATP_OB_N PF17758.1 KFP04306.1 - 0.011 15.3 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain IstB_IS21 PF01695.17 KFP04306.1 - 0.022 14.5 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 KFP04306.1 - 0.042 13.6 0.0 0.28 10.9 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 KFP04306.1 - 0.05 13.3 0.6 0.14 11.9 0.2 2.0 2 1 0 2 2 1 0 AAA domain ATPase PF06745.13 KFP04306.1 - 0.061 12.7 1.2 0.19 11.0 0.0 2.2 3 0 0 3 3 3 0 KaiC Dsl1_C PF11989.8 KFP04306.1 - 0.075 12.8 0.6 0.13 11.9 0.6 1.4 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal DUF3713 PF12506.8 KFP04306.1 - 0.082 13.2 1.6 0.56 10.5 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) AAA_7 PF12775.7 KFP04306.1 - 0.091 12.3 0.0 0.21 11.1 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KFP04306.1 - 0.16 12.4 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 KFP04306.1 - 0.18 11.4 0.8 1.6 8.3 0.2 2.2 1 1 1 2 2 2 0 AAA domain JIP_LZII PF16471.5 KFP04306.1 - 0.48 10.6 6.4 1.1 9.4 6.4 1.6 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II Claudin_2 PF13903.6 KFP04307.1 - 8.6e-13 48.5 5.1 1e-12 48.2 5.1 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFP04307.1 - 0.019 14.8 8.3 0.027 14.3 8.3 1.3 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF3961 PF13106.6 KFP04307.1 - 0.14 11.8 1.1 0.27 10.9 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) Zip PF02535.22 KFP04308.1 - 1.9e-55 188.5 7.9 6.3e-55 186.7 7.9 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter ABC2_membrane_3 PF12698.7 KFP04308.1 - 1 8.4 4.6 0.18 10.8 0.3 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein Ets PF00178.22 KFP04309.1 - 2.3e-23 82.5 2.9 3.7e-23 81.8 2.9 1.3 1 0 0 1 1 1 1 Ets-domain I-set PF07679.16 KFP04310.1 - 4.2e-106 347.3 12.6 6.8e-17 61.3 0.0 8.9 8 1 0 8 8 8 8 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP04310.1 - 3.2e-72 239.1 0.9 6.5e-13 49.1 0.0 8.6 8 0 0 8 8 8 8 Immunoglobulin domain ig PF00047.25 KFP04310.1 - 1.3e-43 147.0 3.2 4.7e-08 33.1 0.0 8.4 8 0 0 8 8 8 8 Immunoglobulin domain fn3 PF00041.21 KFP04310.1 - 1.8e-39 134.0 0.0 2.3e-11 43.8 0.0 4.3 4 0 0 4 4 4 3 Fibronectin type III domain Ig_2 PF13895.6 KFP04310.1 - 1.2e-32 112.0 0.3 3.9e-05 23.9 0.0 9.0 7 2 1 8 8 8 6 Immunoglobulin domain THB PF18362.1 KFP04310.1 - 8.1e-22 76.5 0.1 2e-21 75.3 0.1 1.7 1 0 0 1 1 1 1 Tri-helix bundle domain V-set PF07686.17 KFP04310.1 - 6.9e-20 71.2 9.8 0.013 15.6 0.0 11.0 7 5 1 8 8 8 5 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP04310.1 - 1.2e-09 38.1 0.2 0.062 13.4 0.0 6.3 5 1 0 5 5 5 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFP04310.1 - 7.1e-06 26.3 4.3 20 5.7 0.0 6.8 5 1 1 6 6 6 0 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 KFP04310.1 - 0.00089 19.3 1.3 76 3.5 0.0 6.3 7 0 0 7 7 7 0 Izumo-like Immunoglobulin domain PKD_3 PF16820.5 KFP04310.1 - 0.032 14.0 8.8 0.39 10.5 0.1 5.1 6 0 0 6 6 6 0 PKD-like domain Yae1_N PF09811.9 KFP04311.1 - 2e-12 46.6 39.1 1.1e+04 -3.8 39.1 4.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal DENN PF02141.21 KFP04312.1 - 6.4e-33 114.3 2.0 1.6e-32 113.0 2.0 1.7 1 1 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KFP04312.1 - 1.9e-18 66.9 0.8 5.8e-18 65.4 0.8 1.9 1 0 0 1 1 1 1 uDENN domain DEADboxA PF12343.8 KFP04312.1 - 6.3 7.4 6.5 2.8 8.5 1.9 2.4 1 1 1 2 2 2 0 Cold shock protein DEAD box A Hormone_recep PF00104.30 KFP04313.1 - 2.1e-27 96.1 2.0 3.5e-27 95.3 2.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFP04313.1 - 3.7e-19 69.0 6.6 6.8e-19 68.1 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) C1_2 PF03107.16 KFP04313.1 - 0.41 11.0 6.1 1.2 9.5 2.2 2.6 1 1 1 2 2 2 0 C1 domain His_Phos_2 PF00328.22 KFP04314.1 - 2.7e-20 73.1 0.0 3.4e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Tox-MPTase2 PF15638.6 KFP04314.1 - 0.1 12.4 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 2 WD40 PF00400.32 KFP04315.1 - 7.2e-11 42.5 11.5 0.00016 22.4 0.1 6.2 7 0 0 7 7 7 3 WD domain, G-beta repeat ArfGap PF01412.18 KFP04316.1 - 1.1e-27 96.4 1.5 3e-27 95.0 1.5 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PknG_rubred PF16919.5 KFP04316.1 - 0.27 11.4 5.8 0.91 9.7 1.9 2.7 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain TGF_beta PF00019.20 KFP04318.1 - 7.2e-31 107.2 1.2 1.6e-30 106.2 1.2 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFP04318.1 - 8.9e-10 38.7 1.4 6.8e-09 35.8 1.4 2.2 1 1 0 1 1 1 1 TGF-beta propeptide Yae1_N PF09811.9 KFP04319.1 - 1.2e-16 60.1 61.4 0.0037 16.9 8.3 6.0 1 1 3 4 4 4 3 Essential protein Yae1, N terminal zf-C2H2 PF00096.26 KFP04320.1 - 2.3e-20 71.8 30.5 0.00032 21.0 0.5 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP04320.1 - 1.2e-11 44.5 31.0 1.6e-06 28.3 1.4 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP04320.1 - 3.7e-07 30.4 29.0 0.0049 17.6 0.3 6.0 5 0 0 5 5 5 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFP04320.1 - 1.8e-06 28.5 20.5 0.045 14.4 6.7 5.1 1 1 2 4 4 4 2 FOXP coiled-coil domain zf_ZIC PF18366.1 KFP04320.1 - 0.24 11.6 9.4 1.7 8.8 0.6 3.8 1 1 2 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_aberr PF17017.5 KFP04320.1 - 0.98 9.5 15.7 9.3 6.4 2.4 3.4 2 1 1 3 3 3 0 Aberrant zinc-finger PcF PF09461.10 KFP04320.1 - 3.4 8.1 5.4 38 4.7 0.3 3.5 2 1 1 3 3 3 0 Phytotoxin PcF protein zf-H2C2_5 PF13909.6 KFP04320.1 - 9.9 6.0 9.6 2.2 8.1 0.0 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Thiolase_N PF00108.23 KFP04321.1 - 5.2e-90 301.3 0.4 8.2e-90 300.7 0.1 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFP04321.1 - 1e-51 173.7 0.5 2.1e-51 172.7 0.5 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFP04321.1 - 3.9e-05 23.4 1.1 0.0045 16.6 0.5 2.7 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain IZUMO PF15005.6 KFP04322.1 - 0.0038 17.7 3.2 0.0038 17.7 3.2 1.6 2 0 0 2 2 2 1 Izumo sperm-egg fusion, Ig domain-associated bZIP_1 PF00170.21 KFP04322.1 - 0.0039 17.3 15.8 0.038 14.1 7.0 2.4 2 0 0 2 2 2 2 bZIP transcription factor Csm1_N PF18504.1 KFP04322.1 - 0.0077 16.6 15.6 0.048 14.0 2.2 2.5 3 0 0 3 3 2 2 Csm1 N-terminal domain FapA PF03961.13 KFP04322.1 - 0.011 14.4 9.0 0.012 14.3 9.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2508 PF10704.9 KFP04322.1 - 0.011 15.9 2.4 0.011 15.9 2.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2508) LMBR1 PF04791.16 KFP04322.1 - 0.038 12.9 5.0 0.043 12.7 5.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Fez1 PF06818.15 KFP04322.1 - 0.038 14.4 13.6 0.05 14.1 13.6 1.1 1 0 0 1 1 1 0 Fez1 LpqV PF17301.2 KFP04322.1 - 0.047 13.9 0.9 2.4 8.4 0.1 2.1 2 0 0 2 2 2 0 Putative lipoprotein LpqV DUF2492 PF10678.9 KFP04322.1 - 0.069 13.4 1.0 0.12 12.6 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2492) DUF1825 PF08855.10 KFP04322.1 - 0.07 13.1 5.8 0.048 13.6 3.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1825) GAS PF13851.6 KFP04322.1 - 0.14 11.5 21.9 0.12 11.7 9.6 2.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 KFP04322.1 - 0.16 12.5 21.5 0.34 11.4 21.1 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region Clr5 PF14420.6 KFP04322.1 - 0.21 11.9 5.5 2.7 8.3 1.9 3.1 2 1 0 2 2 2 0 Clr5 domain betaPIX_CC PF16523.5 KFP04322.1 - 0.33 10.8 12.8 0.58 10.0 5.2 2.3 1 1 0 2 2 2 0 betaPIX coiled coil Amidinotransf PF02274.17 KFP04322.1 - 0.34 10.0 4.9 0.44 9.6 4.9 1.1 1 0 0 1 1 1 0 Amidinotransferase DUF4407 PF14362.6 KFP04322.1 - 0.37 10.1 5.8 0.49 9.7 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 KFP04322.1 - 0.44 11.0 7.2 4.7 7.8 1.5 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ECH_2 PF16113.5 KFP04322.1 - 0.52 9.7 3.9 0.58 9.6 3.9 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Uteroglobin PF01099.17 KFP04322.1 - 0.68 10.3 4.4 0.99 9.8 0.0 2.6 3 1 0 3 3 2 0 Uteroglobin family TMF_TATA_bd PF12325.8 KFP04322.1 - 0.72 10.1 19.3 2.1 8.6 8.1 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF812 PF05667.11 KFP04322.1 - 0.76 8.6 14.9 0.94 8.3 14.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Phage_GP20 PF06810.11 KFP04322.1 - 0.89 9.4 15.0 0.78 9.5 2.1 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 Prefoldin PF02996.17 KFP04322.1 - 1.1 9.2 11.9 1.1 9.2 1.4 2.4 3 0 0 3 3 2 0 Prefoldin subunit Seryl_tRNA_N PF02403.22 KFP04322.1 - 1.2 9.4 12.5 19 5.5 12.5 2.2 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4795 PF16043.5 KFP04322.1 - 1.3 8.6 14.2 2.4 7.7 14.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) ALMT PF11744.8 KFP04322.1 - 1.5 7.6 5.4 1.7 7.4 5.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter TolA_bind_tri PF16331.5 KFP04322.1 - 1.7 8.8 15.8 4.1 7.5 5.6 2.4 1 1 1 2 2 2 0 TolA binding protein trimerisation V_ATPase_I PF01496.19 KFP04322.1 - 1.7 6.5 10.7 2 6.2 10.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.9 KFP04322.1 - 1.7 8.6 21.5 3.8 7.5 21.5 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Uso1_p115_C PF04871.13 KFP04322.1 - 2.2 8.7 16.0 0.98 9.8 11.3 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Histidinol_dh PF00815.20 KFP04322.1 - 2.2 7.2 4.4 3 6.7 4.4 1.2 1 0 0 1 1 1 0 Histidinol dehydrogenase SEO_N PF14576.6 KFP04322.1 - 2.5 7.2 6.9 0.6 9.2 2.1 1.9 1 1 1 2 2 2 0 Sieve element occlusion N-terminus Jnk-SapK_ap_N PF09744.9 KFP04322.1 - 2.7 8.2 21.2 5 7.3 21.2 1.5 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Prominin PF05478.11 KFP04322.1 - 6 4.7 8.1 7.7 4.3 8.1 1.1 1 0 0 1 1 1 0 Prominin TPD52 PF04201.15 KFP04322.1 - 6.6 6.3 10.7 4.8 6.8 9.5 1.5 1 1 0 1 1 1 0 Tumour protein D52 family HU-CCDC81_bac_2 PF18175.1 KFP04322.1 - 6.7 6.7 8.0 13 5.7 1.9 2.4 1 1 1 2 2 2 0 CCDC81-like prokaryotic HU domain 2 PRKG1_interact PF15898.5 KFP04322.1 - 6.9 7.6 17.9 3 8.8 6.8 2.4 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Speriolin_N PF15058.6 KFP04322.1 - 8.1 6.5 8.2 0.89 9.6 2.1 2.0 1 1 1 2 2 2 0 Speriolin N terminus Rx_N PF18052.1 KFP04322.1 - 8.2 6.8 11.9 2.9 8.2 4.3 2.3 1 1 1 2 2 2 0 Rx N-terminal domain CENP-H PF05837.12 KFP04322.1 - 9 6.7 15.7 3.2 8.2 6.7 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Cnn_1N PF07989.11 KFP04322.1 - 9.8 6.4 18.8 12 6.1 16.1 2.4 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 F-box-like PF12937.7 KFP04326.1 - 5.6e-11 42.2 2.3 7.9e-11 41.7 0.8 2.1 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KFP04326.1 - 4.9e-09 35.8 0.6 4.9e-09 35.8 0.6 2.3 2 0 0 2 2 2 1 F-box domain Peptidase_M23 PF01551.22 KFP04327.1 - 9.4e-10 38.6 0.1 0.00048 20.3 0.0 3.0 2 1 0 2 2 2 2 Peptidase family M23 PRRSV_2b PF07069.11 KFP04327.1 - 0.19 12.2 0.3 13 6.4 0.1 2.4 2 0 0 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b Fasciclin PF02469.22 KFP04328.1 - 1.5e-102 338.8 3.4 1.2e-32 112.8 0.2 4.2 4 0 0 4 4 4 4 Fasciclin domain Fibrillin_U_N PF18193.1 KFP04328.1 - 1.1 9.5 6.3 1.1 9.5 1.8 2.4 2 0 0 2 2 2 0 Fibrillin 1 unique N-terminal domain MH2 PF03166.14 KFP04329.1 - 6e-76 254.8 1.4 8.4e-76 254.3 1.4 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 KFP04329.1 - 2.6e-42 143.2 0.3 5.9e-42 142.1 0.3 1.6 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.9 KFP04329.1 - 0.00015 21.6 0.0 0.00025 20.9 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 DUF4223 PF13978.6 KFP04329.1 - 0.13 12.2 0.8 0.27 11.2 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) Ion_trans PF00520.31 KFP04330.1 - 4.5e-34 117.8 34.5 9.9e-24 83.9 27.1 2.1 2 0 0 2 2 2 2 Ion transport protein Yae1_N PF09811.9 KFP04331.1 - 4.5e-14 51.8 56.1 5.7 6.7 1.0 5.9 2 1 0 2 2 2 1 Essential protein Yae1, N terminal Cyclin_N PF00134.23 KFP04332.1 - 3.1e-38 130.4 2.4 3.1e-38 130.4 2.4 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP04332.1 - 7.9e-21 74.3 2.8 1.5e-20 73.4 0.4 2.3 2 1 1 3 3 3 1 Cyclin, C-terminal domain Yae1_N PF09811.9 KFP04333.1 - 6.5e-11 41.7 6.6 9.8e-11 41.2 6.6 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal FGF PF00167.18 KFP04334.1 - 8.6e-19 67.9 0.0 1e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 Fibroblast growth factor FGF PF00167.18 KFP04335.1 - 3.7e-32 111.1 0.0 4.4e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor FGF PF00167.18 KFP04336.1 - 4.7e-36 123.6 0.1 5.3e-36 123.5 0.1 1.0 1 0 0 1 1 1 1 Fibroblast growth factor Anoctamin PF04547.12 KFP04337.1 - 1.2e-144 482.5 5.8 3.6e-86 289.8 0.1 2.2 1 1 1 2 2 2 2 Calcium-activated chloride channel Anoct_dimer PF16178.5 KFP04337.1 - 3e-84 282.3 0.9 3e-84 282.3 0.9 2.5 3 0 0 3 3 3 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Ni_hydr_CYTB PF01292.20 KFP04337.1 - 0.048 13.3 0.2 0.13 11.9 0.2 1.7 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DED PF01335.21 KFP04338.1 - 3.2e-19 69.0 3.3 5.4e-19 68.3 3.3 1.4 1 0 0 1 1 1 1 Death effector domain Death PF00531.22 KFP04338.1 - 1.2e-17 63.9 0.6 3.6e-16 59.1 0.3 2.2 2 0 0 2 2 2 1 Death domain eIF-4B PF06273.11 KFP04338.1 - 0.26 10.3 0.4 0.3 10.1 0.4 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B SAM_1 PF00536.30 KFP04339.1 - 1.1e-23 83.4 0.3 7.4e-12 45.5 0.1 3.8 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP04339.1 - 7e-22 77.3 0.2 6.3e-08 32.6 0.1 3.6 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) DUF4472 PF14739.6 KFP04339.1 - 0.016 15.9 13.9 0.016 15.9 13.9 6.5 3 2 3 6 6 6 0 Domain of unknown function (DUF4472) DUF5082 PF16888.5 KFP04339.1 - 0.14 12.4 0.0 0.14 12.4 0.0 7.1 4 2 2 7 7 7 0 Domain of unknown function (DUF5082) HWE_HK PF07536.14 KFP04339.1 - 0.19 12.5 23.8 0.17 12.6 2.5 6.1 3 1 3 6 6 6 0 HWE histidine kinase Yae1_N PF09811.9 KFP04340.1 - 3.5e-14 52.2 35.3 0.0022 17.7 4.7 4.1 1 1 1 2 2 2 2 Essential protein Yae1, N terminal HS1_rep PF02218.15 KFP04341.1 - 1.5e-110 361.2 67.2 1.2e-21 76.8 3.5 7.3 7 0 0 7 7 7 6 Repeat in HS1/Cortactin SH3_9 PF14604.6 KFP04341.1 - 2.4e-17 62.5 0.2 5.3e-17 61.4 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP04341.1 - 1.7e-16 59.6 0.2 4.3e-16 58.2 0.2 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP04341.1 - 4.5e-10 39.0 0.0 1.1e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain TMEM210 PF15195.6 KFP04341.1 - 1.7e-07 31.7 5.6 11 6.5 0.0 6.2 1 1 5 6 6 6 4 TMEM210 family AMP-binding_C_2 PF14535.6 KFP04341.1 - 0.095 13.0 4.8 0.23 11.8 0.4 3.2 3 1 0 3 3 3 0 AMP-binding enzyme C-terminal domain Tho2 PF11262.8 KFP04341.1 - 0.55 9.4 7.2 1.1 8.4 7.2 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Ank_2 PF12796.7 KFP04342.1 - 1.2e-23 83.5 7.5 3e-10 40.5 0.2 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) SAM_1 PF00536.30 KFP04342.1 - 4e-20 72.0 0.2 9.9e-20 70.8 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank_4 PF13637.6 KFP04342.1 - 2e-19 69.7 4.1 6.3e-07 29.8 1.1 4.7 3 1 2 5 5 5 3 Ankyrin repeats (many copies) SAM_2 PF07647.17 KFP04342.1 - 3.2e-18 65.6 0.2 6.9e-18 64.5 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank PF00023.30 KFP04342.1 - 4.7e-16 58.4 8.0 0.0035 17.7 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 KFP04342.1 - 9e-14 50.3 2.7 0.66 10.7 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KFP04342.1 - 2.5e-13 50.0 4.1 4.1e-06 27.0 0.1 4.5 2 2 3 5 5 5 3 Ankyrin repeats (many copies) SH3_2 PF07653.17 KFP04342.1 - 5.3e-13 48.4 0.5 1.2e-12 47.4 0.5 1.6 1 0 0 1 1 1 1 Variant SH3 domain PDZ_6 PF17820.1 KFP04342.1 - 5.7e-10 38.9 0.2 3.2e-09 36.5 0.2 2.3 2 0 0 2 2 2 1 PDZ domain SH3_9 PF14604.6 KFP04342.1 - 2.2e-09 37.0 0.0 5.5e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PDZ PF00595.24 KFP04342.1 - 3.1e-08 33.8 0.0 1.3e-07 31.9 0.0 2.1 1 0 0 1 1 1 1 PDZ domain FERM_f0 PF16511.5 KFP04342.1 - 8.3e-07 29.2 0.0 2.6e-06 27.6 0.0 1.8 2 0 0 2 2 1 1 N-terminal or F0 domain of Talin-head FERM SH3_1 PF00018.28 KFP04342.1 - 4.1e-06 26.3 0.0 8.2e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SAM_4 PF18017.1 KFP04342.1 - 0.046 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFP04342.1 - 0.19 11.7 0.0 0.44 10.6 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain UPAR_LY6 PF00021.21 KFP04343.1 - 0.035 14.8 12.4 0.18 12.6 12.4 2.0 1 1 0 1 1 1 0 u-PAR/Ly-6 domain DUF525 PF04379.14 KFP04344.1 - 1.1e-29 102.5 0.1 3.4e-29 100.9 0.1 1.9 2 0 0 2 2 2 1 ApaG domain SMI1_KNR4 PF09346.10 KFP04344.1 - 2.3e-10 41.0 0.0 5.8e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 KFP04344.1 - 0.003 18.0 0.0 0.0088 16.5 0.0 1.9 1 1 0 1 1 1 1 SMI1-KNR4 cell-wall SUKH_5 PF14567.6 KFP04344.1 - 0.034 13.9 0.0 0.087 12.6 0.0 1.7 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall LIM PF00412.22 KFP04345.1 - 1.5e-28 98.7 20.8 1.1e-15 57.6 9.0 2.0 2 0 0 2 2 2 2 LIM domain C1_4 PF07975.12 KFP04345.1 - 0.019 15.2 5.4 0.019 15.2 5.4 2.6 2 1 0 2 2 2 0 TFIIH C1-like domain TDH PF03347.13 KFP04345.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Vibrio thermostable direct hemolysin Caprin-1_dimer PF18293.1 KFP04346.1 - 2.1e-34 118.4 0.5 2.1e-34 118.4 0.5 1.9 2 0 0 2 2 2 1 Caprin-1 dimerization domain RBFA PF02033.18 KFP04346.1 - 0.038 14.4 0.4 0.067 13.6 0.4 1.4 1 0 0 1 1 1 0 Ribosome-binding factor A Aida_N PF08910.10 KFP04346.1 - 0.17 12.3 2.4 0.31 11.5 2.3 1.5 1 1 0 1 1 1 0 Aida N-terminus SKIP_SNW PF02731.15 KFP04346.1 - 3.3 7.4 7.6 5.1 6.7 7.6 1.3 1 0 0 1 1 1 0 SKIP/SNW domain GNAT_acetyltr_2 PF13718.6 KFP04347.1 - 2.4e-91 305.2 0.3 1.1e-90 303.0 0.0 2.2 3 0 0 3 3 3 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KFP04347.1 - 1.3e-80 270.5 3.6 2.6e-80 269.5 3.6 1.5 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KFP04347.1 - 3.7e-65 219.1 0.1 1.2e-64 217.5 0.0 2.0 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KFP04347.1 - 5.3e-35 119.2 0.1 1.4e-34 117.9 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 KFP04347.1 - 8.3e-05 22.4 0.0 0.31 10.7 0.0 2.7 2 1 0 2 2 2 2 AAA domain Acetyltransf_7 PF13508.7 KFP04347.1 - 0.00055 20.3 0.0 0.0031 17.9 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_22 PF13401.6 KFP04347.1 - 0.0013 19.1 0.1 1.9 8.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain Acetyltransf_1 PF00583.25 KFP04347.1 - 0.0029 17.8 0.0 0.0086 16.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Focal_AT PF03623.13 KFP04347.1 - 0.038 14.0 2.7 0.05 13.6 1.1 2.0 2 0 0 2 2 2 0 Focal adhesion targeting region Acetyltransf_10 PF13673.7 KFP04347.1 - 0.13 12.2 0.0 5.6 6.9 0.0 3.2 4 0 0 4 4 4 0 Acetyltransferase (GNAT) domain BTB PF00651.31 KFP04348.1 - 6.5e-24 84.3 0.7 1.6e-23 83.0 0.6 1.8 1 1 0 1 1 1 1 BTB/POZ domain Ank_2 PF12796.7 KFP04348.1 - 1.9e-20 73.2 0.0 2.7e-11 43.9 0.0 4.0 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP04348.1 - 7.3e-16 58.3 0.2 8.1e-10 39.0 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP04348.1 - 9.1e-16 56.4 0.9 5.4e-05 23.3 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KFP04348.1 - 1.1e-13 50.9 4.5 2.1e-05 24.7 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KFP04348.1 - 4.4e-11 42.8 2.0 0.0029 17.9 0.0 5.0 3 1 2 5 5 5 3 Ankyrin repeats (many copies) BACK PF07707.15 KFP04348.1 - 0.001 19.2 0.4 0.0038 17.3 0.1 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch LAGLIDADG_2 PF03161.13 KFP04348.1 - 0.14 12.1 0.5 0.31 11.0 0.5 1.6 1 0 0 1 1 1 0 LAGLIDADG DNA endonuclease family Catalase PF00199.19 KFP04349.1 - 2.6e-197 655.5 0.0 3.4e-197 655.1 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KFP04349.1 - 5.2e-20 71.4 0.9 1.4e-19 70.1 0.3 2.0 2 0 0 2 2 2 1 Catalase-related immune-responsive FA_desaturase PF00487.24 KFP04350.1 - 1e-32 114.0 23.7 1e-32 114.0 23.7 1.4 1 1 1 2 2 2 1 Fatty acid desaturase FA_desaturase PF00487.24 KFP04351.1 - 1.7e-06 28.1 1.9 1.9e-06 28.0 1.9 1.0 1 0 0 1 1 1 1 Fatty acid desaturase Thiol_cytolysin PF01289.19 KFP04351.1 - 0.08 11.8 0.2 0.083 11.8 0.2 1.0 1 0 0 1 1 1 0 Thiol-activated cytolysin Cyt-b5 PF00173.28 KFP04352.1 - 1.1e-18 67.2 0.1 1.9e-18 66.4 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 KFP04352.1 - 7.4e-12 45.6 2.6 7.4e-12 45.6 2.6 2.1 1 1 1 2 2 2 2 Fatty acid desaturase FA_desaturase PF00487.24 KFP04353.1 - 2.1e-22 80.2 27.5 2.1e-22 80.2 27.5 1.9 1 1 1 2 2 2 2 Fatty acid desaturase FA_desaturase PF00487.24 KFP04354.1 - 1.1e-28 100.7 24.6 1.9e-26 93.4 22.0 2.9 1 1 1 2 2 2 2 Fatty acid desaturase Cyt-b5 PF00173.28 KFP04354.1 - 1.6e-21 76.2 0.0 2.9e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CHDNT PF08073.12 KFP04354.1 - 0.054 13.5 0.0 0.2 11.7 0.0 1.9 1 0 0 1 1 1 0 CHDNT (NUC034) domain EpuA PF11772.8 KFP04354.1 - 0.079 12.7 0.2 0.45 10.2 0.1 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta Sec2p PF06428.11 KFP04355.1 - 8.2e-09 35.3 10.7 8.2e-09 35.3 10.7 2.3 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p AviRa PF11599.8 KFP04355.1 - 0.037 13.5 1.0 0.053 13.0 1.0 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa IATP PF04568.12 KFP04355.1 - 0.058 13.8 1.8 0.16 12.4 1.8 1.8 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Spc7 PF08317.11 KFP04355.1 - 0.096 11.5 14.6 0.15 10.9 14.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KFP04355.1 - 0.11 12.6 14.7 0.23 11.5 14.7 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 KFP04355.1 - 0.34 10.2 5.8 0.51 9.6 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cob_adeno_trans PF01923.18 KFP04355.1 - 0.34 11.0 5.3 1.9 8.6 5.1 2.1 1 1 0 1 1 1 0 Cobalamin adenosyltransferase UPF0242 PF06785.11 KFP04355.1 - 0.6 10.2 14.1 0.99 9.5 14.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HSP70 PF00012.20 KFP04355.1 - 0.75 7.9 9.5 1.1 7.3 9.5 1.2 1 0 0 1 1 1 0 Hsp70 protein DUF2203 PF09969.9 KFP04355.1 - 1 10.1 6.1 2.5 8.8 6.1 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Borrelia_P83 PF05262.11 KFP04355.1 - 1.1 7.7 7.9 1.5 7.3 7.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein GlutR_dimer PF00745.20 KFP04355.1 - 1.3 9.5 8.1 3.7 8.1 7.8 1.9 1 1 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain Exonuc_VII_L PF02601.15 KFP04355.1 - 2.3 7.7 7.8 3.2 7.2 7.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 KFP04355.1 - 3.1 7.9 5.4 9.6 6.3 5.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Uds1 PF15456.6 KFP04355.1 - 3.6 7.8 14.8 2.1 8.5 7.0 2.6 1 1 1 2 2 2 0 Up-regulated During Septation Syntaxin-6_N PF09177.11 KFP04355.1 - 4.4 7.9 9.7 12 6.5 8.4 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal FapA PF03961.13 KFP04355.1 - 6.9 5.2 8.3 9.4 4.7 8.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A XhlA PF10779.9 KFP04355.1 - 8 6.7 10.1 0.58 10.4 2.0 2.3 1 1 1 2 2 2 0 Haemolysin XhlA Bestrophin PF01062.21 KFP04356.1 - 1.2e-109 366.3 3.3 1.4e-109 366.0 3.3 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Ferritin PF00210.24 KFP04357.1 - 3.5e-31 108.0 2.5 4.1e-31 107.8 2.5 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 KFP04357.1 - 0.0041 17.5 0.3 0.0051 17.2 0.3 1.3 1 0 0 1 1 1 1 Rubrerythrin FCH PF00611.23 KFP04357.1 - 0.1 12.9 2.9 0.19 12.0 2.9 1.7 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Ferritin PF00210.24 KFP04358.1 - 3.9e-31 107.9 2.7 4.5e-31 107.7 2.7 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 KFP04358.1 - 0.0029 18.0 0.6 0.0036 17.7 0.6 1.2 1 0 0 1 1 1 1 Rubrerythrin IcmF_C PF06744.12 KFP04358.1 - 0.042 13.5 0.0 0.046 13.3 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion protein IcmF C-terminal FCH PF00611.23 KFP04358.1 - 0.069 13.4 1.8 0.12 12.6 1.8 1.5 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain 7tm_4 PF13853.6 KFP04359.1 - 2.5e-53 181.6 22.0 2.9e-53 181.4 22.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP04359.1 - 2.1e-29 102.7 24.6 3.6e-29 101.9 24.6 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP04359.1 - 0.00015 21.2 11.9 0.00015 21.2 11.9 2.3 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP04359.1 - 0.022 14.4 23.7 0.089 12.4 23.7 1.9 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx SLC3A2_N PF16028.5 KFP04359.1 - 0.098 12.2 1.4 0.62 9.7 0.1 2.5 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus 7tm_4 PF13853.6 KFP04360.1 - 1.6e-20 74.0 2.9 1.8e-20 73.8 2.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP04360.1 - 1.3e-16 60.7 0.7 1.8e-16 60.3 0.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP04360.1 - 5.6e-05 22.6 2.0 7e-05 22.3 2.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2842 PF11003.8 KFP04360.1 - 8.7 6.7 8.4 1.7 9.0 1.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2842) 7tm_4 PF13853.6 KFP04361.1 - 5.1e-51 174.0 18.0 6e-51 173.8 18.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP04361.1 - 1.9e-30 106.1 15.8 2.7e-30 105.6 15.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP04361.1 - 3.8e-06 26.5 14.2 6.1e-06 25.8 14.2 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP04361.1 - 0.00046 19.9 11.3 0.00046 19.9 11.3 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx SLC3A2_N PF16028.5 KFP04361.1 - 0.075 12.6 0.5 0.24 11.0 0.1 2.0 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus 7tm_4 PF13853.6 KFP04362.1 - 4.3e-46 157.9 16.1 5.8e-46 157.5 16.1 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP04362.1 - 2e-24 86.3 24.3 3.3e-24 85.6 24.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP04362.1 - 3.6e-05 23.3 22.1 0.00016 21.1 22.0 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP04362.1 - 0.0022 17.6 14.0 0.0022 17.6 14.0 2.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx SLC3A2_N PF16028.5 KFP04362.1 - 0.16 11.6 2.1 1.3 8.6 0.1 2.5 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus 7tm_4 PF13853.6 KFP04363.1 - 1.4e-45 156.2 19.4 1.8e-45 155.9 19.4 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP04363.1 - 1.6e-21 76.9 24.2 2.7e-21 76.1 24.2 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP04363.1 - 2.9e-06 26.9 20.8 5.7e-06 25.9 20.8 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP04363.1 - 9e-05 22.2 16.4 9e-05 22.2 16.4 2.5 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx SLC3A2_N PF16028.5 KFP04363.1 - 0.67 9.5 2.7 14 5.3 0.2 2.8 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus 7tm_4 PF13853.6 KFP04364.1 - 1.1e-46 159.8 21.2 1.3e-46 159.6 21.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP04364.1 - 4.9e-26 91.6 22.6 8.7e-26 90.8 22.6 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP04364.1 - 9.7e-05 21.9 21.1 0.00043 19.7 21.1 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 KFP04365.1 - 4.9e-07 29.4 11.7 2.1e-06 27.3 11.7 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srbc PF10316.9 KFP04365.1 - 0.00032 20.3 0.8 0.00032 20.3 0.8 2.4 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc RseC_MucC PF04246.12 KFP04365.1 - 5.6 6.9 5.5 2.6 8.0 2.0 2.0 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Tom5 PF10642.9 KFP04366.1 - 1.6e-09 37.6 0.0 1.8e-09 37.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase DUF1077 PF06417.12 KFP04367.1 - 7.5e-14 51.8 0.3 7.8e-14 51.7 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DnaJ_C PF01556.18 KFP04370.1 - 5.2e-41 140.2 0.0 6.7e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFP04370.1 - 4.9e-20 71.4 0.2 8e-20 70.7 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KFP04370.1 - 5.1e-13 49.2 19.9 8.4e-13 48.5 19.9 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KFP04370.1 - 0.026 14.5 9.1 0.065 13.3 0.6 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 KFP04370.1 - 0.13 12.3 15.1 0.27 11.2 4.1 2.9 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Ribosomal_L32p PF01783.23 KFP04370.1 - 6.9 7.0 8.7 3.7 7.9 0.9 2.5 2 0 0 2 2 2 0 Ribosomal L32p protein family Filament PF00038.21 KFP04371.1 - 1.3e-23 84.1 28.6 1.6e-23 83.7 28.6 1.1 1 0 0 1 1 1 1 Intermediate filament protein DUF1664 PF07889.12 KFP04371.1 - 0.13 12.3 4.2 0.49 10.5 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Phlebovirus_NSM PF07246.11 KFP04371.1 - 0.47 9.8 9.5 1.7 7.9 0.0 2.8 3 0 0 3 3 3 0 Phlebovirus nonstructural protein NS-M SPT16 PF08644.11 KFP04371.1 - 4 7.6 6.3 8.8 6.5 6.3 1.7 1 1 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DUF4472 PF14739.6 KFP04371.1 - 4.5 8.0 28.3 3.5 8.4 0.4 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4472) Ammonium_transp PF00909.21 KFP04372.1 - 3.7e-48 164.2 16.4 4.3e-48 164.0 16.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family HKR_ArcB_TM PF18415.1 KFP04372.1 - 0.1 13.4 3.2 0.2 12.5 1.7 2.4 2 0 0 2 2 2 0 Histidine kinase receptor ArcB trans-membrane domain Peptidase_M14 PF00246.24 KFP04373.1 - 2.5e-91 306.5 0.1 3.1e-91 306.2 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KFP04373.1 - 3.3e-23 81.9 1.1 6.3e-23 81.0 0.5 1.9 2 0 0 2 2 2 1 Carboxypeptidase activation peptide Rhodanese PF00581.20 KFP04374.1 - 0.0034 17.9 0.0 0.0084 16.6 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Abhydrolase_1 PF00561.20 KFP04375.1 - 3.7e-08 33.3 0.2 3.5e-07 30.1 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFP04375.1 - 1.1e-07 32.6 0.1 1.3e-07 32.4 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFP04375.1 - 2e-05 24.0 0.1 9.3e-05 21.8 0.1 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 KFP04375.1 - 0.0074 15.4 0.0 0.01 14.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) COP-gamma_platf PF08752.10 KFP04376.1 - 8.6e-22 77.9 0.1 1.4e-21 77.2 0.1 1.3 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Adaptin_N PF01602.20 KFP04376.1 - 0.064 11.8 0.0 0.087 11.4 0.0 1.2 1 0 0 1 1 1 0 Adaptin N terminal region Laminin_G_2 PF02210.24 KFP04378.1 - 9.9e-21 74.6 0.1 7.8e-16 58.8 0.1 2.2 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 KFP04378.1 - 1.7e-14 54.2 0.0 1.7e-10 41.2 0.0 2.1 2 0 0 2 2 2 2 Laminin G domain DUF4154 PF13689.6 KFP04378.1 - 0.046 14.0 0.0 0.069 13.4 0.0 1.4 1 0 0 1 1 1 0 YfiR/HmsC-like DUF3791 PF12668.7 KFP04378.1 - 0.13 12.3 0.1 0.71 10.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) F5_F8_type_C PF00754.25 KFP04379.1 - 1e-17 64.4 2.6 1.2e-17 64.3 2.6 1.0 1 0 0 1 1 1 1 F5/8 type C domain Claudin_2 PF13903.6 KFP04381.1 - 6.9e-19 68.4 1.5 1.1e-18 67.7 1.5 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFP04381.1 - 2.3e-09 37.3 4.9 8.9e-07 28.9 1.1 2.3 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin family SUR7 PF06687.12 KFP04381.1 - 0.00071 19.3 5.9 0.0021 17.8 6.0 1.9 1 1 0 1 1 1 1 SUR7/PalI family TMEM190 PF15431.6 KFP04381.1 - 0.061 13.5 0.2 0.061 13.5 0.2 1.7 2 0 0 2 2 2 0 Transmembrane protein 190 Phospholip_A2_1 PF00068.19 KFP04382.1 - 3.5e-33 114.4 15.4 4.5e-33 114.0 15.4 1.1 1 0 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.10 KFP04382.1 - 0.025 14.7 0.0 0.045 13.9 0.0 1.5 1 0 0 1 1 1 0 Parvovirus coat protein VP1 DHHC PF01529.20 KFP04383.1 - 1.2e-30 106.3 9.1 1.2e-30 106.3 9.1 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Spo7 PF03907.13 KFP04383.1 - 1.5 8.2 3.9 0.88 9.0 1.0 2.0 2 0 0 2 2 2 0 Spo7-like protein DUF347 PF03988.12 KFP04383.1 - 9.7 6.5 11.1 4.2 7.6 2.0 3.2 3 1 0 3 3 3 0 Repeat of Unknown Function (DUF347) TGT PF01702.18 KFP04385.1 - 6.1e-80 269.0 0.0 6.7e-80 268.9 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase 7tm_1 PF00001.21 KFP04386.1 - 4.2e-79 265.6 12.0 6.6e-79 264.9 12.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP04386.1 - 6.6e-12 45.3 14.5 5.6e-09 35.8 13.8 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP04386.1 - 3.6e-05 23.5 14.6 3.6e-05 23.5 14.6 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFP04386.1 - 6.7e-05 22.4 20.7 0.00037 19.9 15.6 2.6 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srv BTB PF00651.31 KFP04387.1 - 6.4e-24 84.3 0.1 1.9e-23 82.8 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2 PF00096.26 KFP04387.1 - 3.1e-22 77.7 42.1 1e-06 28.8 1.9 6.2 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP04387.1 - 3.4e-20 71.5 42.7 1.9e-06 28.0 2.7 7.2 7 1 0 7 7 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP04387.1 - 1e-15 57.0 35.3 0.00021 21.9 1.5 6.1 5 0 0 5 5 5 5 C2H2-type zinc finger zf-met PF12874.7 KFP04387.1 - 1.3e-06 28.6 34.2 0.0035 17.7 1.1 6.0 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KFP04387.1 - 1.1e-05 25.2 6.4 0.43 10.5 0.0 4.4 4 0 0 4 4 4 3 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KFP04387.1 - 4.5e-05 23.3 29.2 0.0024 17.8 0.6 5.6 5 0 0 5 5 5 3 C2H2-type zinc finger BolA PF01722.18 KFP04387.1 - 0.0012 19.1 1.3 0.66 10.3 0.2 3.8 2 1 1 3 3 3 1 BolA-like protein zf-C2H2_2 PF12756.7 KFP04387.1 - 0.0021 18.3 23.8 0.022 15.1 9.3 4.2 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KFP04387.1 - 0.0046 16.7 18.3 0.79 9.5 2.0 4.9 5 0 0 5 5 5 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFP04387.1 - 0.0074 16.6 21.4 0.1 12.9 0.7 4.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFP04387.1 - 0.016 15.5 22.2 1.4 9.3 3.4 4.2 2 1 3 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_11 PF17123.5 KFP04387.1 - 0.22 11.3 8.5 18 5.2 0.0 4.8 5 0 0 5 5 5 0 RING-like zinc finger DUF2225 PF09986.9 KFP04387.1 - 2.2 7.9 13.0 1.4 8.6 0.2 3.9 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) Endonuclease_7 PF02945.15 KFP04387.1 - 4.3 7.3 13.0 1.6 8.7 4.4 3.6 1 1 1 2 2 2 0 Recombination endonuclease VII HNH_5 PF14279.6 KFP04387.1 - 7.3 6.5 13.5 2.3 8.1 0.2 4.0 4 1 0 4 4 4 0 HNH endonuclease Neuromodulin PF06614.11 KFP04389.1 - 1e-61 208.2 68.9 1e-61 208.2 68.9 1.8 2 1 0 2 2 2 1 Neuromodulin Neuromodulin_N PF10580.9 KFP04389.1 - 1.8e-14 53.2 7.5 7.8e-14 51.2 7.5 2.2 1 0 0 1 1 1 1 Gap junction protein N-terminal region IQ PF00612.27 KFP04389.1 - 1.7e-06 27.3 0.4 2.7e-06 26.7 0.4 1.3 1 0 0 1 1 1 1 IQ calmodulin-binding motif I-set PF07679.16 KFP04390.1 - 6.2e-40 135.2 1.5 5.3e-16 58.5 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP04390.1 - 9.9e-40 135.0 3.1 5.5e-17 62.2 0.1 3.1 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFP04390.1 - 9.9e-30 102.7 1.5 5.2e-13 49.1 0.1 3.2 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFP04390.1 - 9.3e-26 89.8 0.8 4.1e-11 42.9 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFP04390.1 - 2.5e-17 63.0 1.1 2.6e-05 24.3 0.0 5.1 3 2 2 5 5 5 4 Immunoglobulin V-set domain Ig_5 PF16681.5 KFP04390.1 - 1.3e-10 41.5 0.1 0.032 14.6 0.0 3.6 3 1 0 3 3 3 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFP04390.1 - 4.2e-08 33.1 0.5 0.0072 16.4 0.1 3.5 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 KFP04390.1 - 4.6e-07 30.0 1.6 0.11 12.8 0.0 4.0 3 2 1 4 4 4 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFP04390.1 - 3.7e-06 26.9 1.0 0.1 12.6 0.0 2.7 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFP04390.1 - 7.1e-06 25.5 0.0 0.068 12.7 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin domain V-set_CD47 PF08204.11 KFP04390.1 - 0.00017 21.6 0.7 0.29 11.1 0.2 3.2 2 1 1 3 3 3 2 CD47 immunoglobulin-like domain Adeno_E3_CR1 PF02440.15 KFP04390.1 - 0.0016 18.1 3.6 4.3 7.2 0.2 4.0 3 1 0 3 3 3 2 Adenovirus E3 region protein CR1 Ig_C17orf99 PF17736.1 KFP04390.1 - 0.0018 18.3 0.9 1 9.4 0.1 4.0 3 2 0 3 3 3 1 C17orf99 Ig domain C2-set PF05790.15 KFP04390.1 - 0.059 13.6 0.1 19 5.5 0.0 3.7 4 0 0 4 4 4 0 Immunoglobulin C2-set domain RVT_1 PF00078.27 KFP04391.1 - 0.0055 16.3 0.0 0.0087 15.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_POL_M_15KD PF02150.16 KFP04392.1 - 1.2e-11 44.3 1.7 1.2e-11 44.3 1.7 1.5 1 1 0 1 1 1 1 RNA polymerases M/15 Kd subunit Pkinase PF00069.25 KFP04393.1 - 4.3e-77 259.0 0.0 5.5e-77 258.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP04393.1 - 1.2e-36 126.3 0.0 1.8e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KFP04393.1 - 1.3e-11 45.0 2.8 2.2e-05 24.9 0.2 2.6 2 0 0 2 2 2 2 PH domain Kinase-like PF14531.6 KFP04393.1 - 3.4e-10 39.7 0.0 2.9e-09 36.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 KFP04393.1 - 2.6e-08 34.4 0.5 5e-08 33.5 0.5 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Seadorna_VP7 PF07387.11 KFP04393.1 - 0.21 10.6 0.0 0.33 10.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PH_11 PF15413.6 KFP04393.1 - 0.52 10.8 2.1 34 4.9 0.4 2.7 3 0 0 3 3 3 0 Pleckstrin homology domain TAF6_C PF07571.13 KFP04394.1 - 4.4e-16 59.0 0.0 6.8e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain zf-H2C2_2 PF13465.6 KFP04396.1 - 2.3e-30 103.7 46.9 1.8e-09 37.6 2.0 6.1 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFP04396.1 - 2.6e-24 84.2 41.8 6.5e-06 26.3 5.3 6.0 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP04396.1 - 1e-15 57.1 39.6 0.00055 20.6 2.8 5.6 6 0 0 6 6 5 4 C2H2-type zinc finger zf_UBZ PF18439.1 KFP04396.1 - 1.4e-07 31.0 19.7 0.1 12.2 0.0 5.4 4 1 2 6 6 6 4 Ubiquitin-Binding Zinc Finger zinc_ribbon_9 PF14369.6 KFP04396.1 - 4.4e-07 30.0 9.9 0.029 14.6 0.1 4.5 4 0 0 4 4 4 2 zinc-ribbon Zn-ribbon_8 PF09723.10 KFP04396.1 - 2e-06 27.8 19.0 0.0026 17.8 1.6 4.2 2 1 2 4 4 4 4 Zinc ribbon domain zf-C2H2_jaz PF12171.8 KFP04396.1 - 3.1e-06 27.3 15.7 0.16 12.3 0.5 5.0 5 0 0 5 5 4 2 Zinc-finger double-stranded RNA-binding XPA_N PF01286.18 KFP04396.1 - 8.8e-06 25.7 14.5 2.5 8.2 0.0 5.2 5 0 0 5 5 5 1 XPA protein N-terminal zf-trcl PF13451.6 KFP04396.1 - 1.7e-05 24.6 15.8 0.15 12.0 3.1 5.0 4 1 0 4 4 4 2 Probable zinc-ribbon domain zf-C2H2_6 PF13912.6 KFP04396.1 - 1.9e-05 24.5 33.5 0.15 12.1 1.6 6.6 6 1 0 6 6 6 3 C2H2-type zinc finger GAGA PF09237.11 KFP04396.1 - 2e-05 24.3 0.5 0.15 11.9 0.0 2.5 1 1 1 2 2 2 2 GAGA factor DZR PF12773.7 KFP04396.1 - 0.00018 21.4 15.8 0.011 15.8 7.9 3.3 2 2 0 2 2 2 1 Double zinc ribbon zf-C2H2_11 PF16622.5 KFP04396.1 - 0.00038 20.2 25.4 0.024 14.4 2.8 5.1 5 0 0 5 5 5 1 zinc-finger C2H2-type Evr1_Alr PF04777.13 KFP04396.1 - 0.00038 20.9 12.0 1.1 9.7 0.3 3.9 1 1 3 4 4 4 2 Erv1 / Alr family zf-Di19 PF05605.12 KFP04396.1 - 0.00097 19.4 18.5 0.0053 17.0 1.8 4.0 2 1 1 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_15 PF17032.5 KFP04396.1 - 0.0012 19.6 11.2 1 10.2 3.9 3.0 1 1 1 2 2 2 2 zinc-ribbon family zf-RING_7 PF02591.15 KFP04396.1 - 0.0016 18.5 8.9 1.1 9.5 0.1 4.2 4 0 0 4 4 4 1 C4-type zinc ribbon domain HypA PF01155.19 KFP04396.1 - 0.0018 18.3 11.0 8.7 6.4 7.3 3.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-AN1 PF01428.16 KFP04396.1 - 0.0031 17.6 19.0 3.1 8.0 0.6 4.6 5 0 0 5 5 4 0 AN1-like Zinc finger zf-LYAR PF08790.11 KFP04396.1 - 0.0033 17.3 17.2 1.6 8.7 0.6 5.3 5 0 0 5 5 5 1 LYAR-type C2HC zinc finger DUF2256 PF10013.9 KFP04396.1 - 0.0041 17.2 10.4 14 5.9 0.1 5.1 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc-ribbons_6 PF07191.12 KFP04396.1 - 0.0053 16.7 15.3 3.2 7.8 0.4 4.0 2 1 0 2 2 2 0 zinc-ribbons zf-HIT PF04438.16 KFP04396.1 - 0.0056 16.5 14.6 0.59 10.1 0.3 4.3 4 0 0 4 4 4 2 HIT zinc finger zf-C2HC_2 PF13913.6 KFP04396.1 - 0.0063 16.4 0.6 0.2 11.6 0.2 4.7 5 0 0 5 5 4 2 zinc-finger of a C2HC-type HscB_4_cys PF18256.1 KFP04396.1 - 0.015 15.1 8.9 5.3 6.9 0.1 4.3 4 0 0 4 4 4 0 Co-chaperone HscB tetracysteine metal binding motif TerY_C PF15616.6 KFP04396.1 - 0.018 15.1 1.6 0.018 15.1 1.6 2.8 1 1 2 3 3 3 0 TerY-C metal binding domain CpXC PF14353.6 KFP04396.1 - 0.019 15.0 13.8 7.7 6.6 0.7 4.5 1 1 3 4 4 4 0 CpXC protein BolA PF01722.18 KFP04396.1 - 0.039 14.2 1.2 0.039 14.2 1.2 2.1 3 0 0 3 3 1 0 BolA-like protein YhfH PF14149.6 KFP04396.1 - 0.046 13.7 14.2 3.8 7.6 0.4 4.9 5 0 0 5 5 5 0 YhfH-like protein zf-C2H2_9 PF16293.5 KFP04396.1 - 0.063 13.1 3.4 23 4.9 0.1 3.6 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) LIM PF00412.22 KFP04396.1 - 0.08 13.2 18.1 0.12 12.6 2.7 4.1 1 1 3 4 4 4 0 LIM domain C1_4 PF07975.12 KFP04396.1 - 0.12 12.6 16.7 0.88 9.9 0.7 3.7 1 1 2 4 4 4 0 TFIIH C1-like domain DUF3268 PF11672.8 KFP04396.1 - 0.18 12.2 8.7 0.47 10.8 0.3 3.1 1 1 4 5 5 5 0 zinc-finger-containing domain zinc_ribbon_4 PF13717.6 KFP04396.1 - 0.18 11.8 16.2 11 6.1 0.3 4.5 5 0 0 5 5 4 0 zinc-ribbon domain zf-RING_4 PF14570.6 KFP04396.1 - 0.21 11.4 11.8 2.1 8.2 0.1 3.7 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain TFIIS_C PF01096.18 KFP04396.1 - 0.31 10.9 16.7 13 5.8 0.8 4.9 5 0 0 5 5 5 0 Transcription factor S-II (TFIIS) FYDLN_acid PF09538.10 KFP04396.1 - 0.34 11.6 8.1 30 5.4 1.0 3.7 2 1 1 3 3 3 0 Protein of unknown function (FYDLN_acid) zf_C2H2_13 PF18508.1 KFP04396.1 - 0.36 10.4 5.9 25 4.6 0.0 3.6 4 0 0 4 4 3 0 Zinc finger domain ADK_lid PF05191.14 KFP04396.1 - 0.38 10.8 9.0 3 7.9 0.3 4.5 4 2 1 5 5 5 0 Adenylate kinase, active site lid zf-ribbon_3 PF13248.6 KFP04396.1 - 0.49 9.9 20.2 0.5 9.9 0.2 4.5 5 0 0 5 5 4 0 zinc-ribbon domain zf-UBR PF02207.20 KFP04396.1 - 0.5 10.6 20.6 1.6 8.9 6.5 4.0 1 1 1 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Zn_ribbon_SprT PF17283.2 KFP04396.1 - 0.62 10.0 20.4 5.4 7.0 0.4 4.5 3 2 0 3 3 3 0 SprT-like zinc ribbon domain T4_baseplate PF12322.8 KFP04396.1 - 0.85 9.0 3.9 13 5.2 0.0 3.3 2 1 2 4 4 4 0 T4 bacteriophage base plate protein Zn_Tnp_IS1595 PF12760.7 KFP04396.1 - 1 9.4 24.3 0.79 9.8 4.7 3.8 2 2 0 3 3 3 0 Transposase zinc-ribbon domain PHD PF00628.29 KFP04396.1 - 1.1 9.2 13.6 3.6 7.6 4.7 3.4 3 0 0 3 3 3 0 PHD-finger YacG PF03884.14 KFP04396.1 - 1.3 8.8 11.9 7 6.5 0.1 4.6 5 0 0 5 5 5 0 DNA gyrase inhibitor YacG PyrI_C PF02748.15 KFP04396.1 - 1.5 8.8 9.8 3.6 7.6 0.1 3.6 4 0 0 4 4 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Yippee-Mis18 PF03226.14 KFP04396.1 - 1.7 8.9 8.8 16 5.7 0.4 3.3 2 1 1 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zf_RING PF16744.5 KFP04396.1 - 2.1 8.5 13.9 3.1 8.0 0.2 3.8 1 1 3 4 4 4 0 KIAA1045 RING finger zf-RING_5 PF14634.6 KFP04396.1 - 2.3 8.3 17.5 27 4.8 0.1 3.9 3 2 0 3 3 3 0 zinc-RING finger domain TRAF6_Z2 PF18048.1 KFP04396.1 - 2.4 8.3 15.1 12 6.1 0.1 4.2 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 Arc_trans_TRASH PF08394.10 KFP04396.1 - 2.8 8.3 0.0 2.8 8.3 0.0 4.2 3 1 1 4 4 4 0 Archaeal TRASH domain Mut7-C PF01927.16 KFP04396.1 - 3.3 7.8 16.1 13 5.8 0.2 3.9 2 1 2 4 4 4 0 Mut7-C RNAse domain zinc_ribbon_5 PF13719.6 KFP04396.1 - 3.5 7.5 17.5 2 8.3 0.2 4.5 5 0 0 5 5 4 0 zinc-ribbon domain Nudix_N_2 PF14803.6 KFP04396.1 - 4 7.4 13.9 19 5.3 0.1 4.5 4 1 0 4 4 3 0 Nudix N-terminal Rubredoxin_2 PF18073.1 KFP04396.1 - 5.7 6.8 19.6 3.5 7.5 0.7 4.9 5 0 0 5 5 4 0 Rubredoxin metal binding domain DNA_RNApol_7kD PF03604.13 KFP04396.1 - 5.7 6.7 14.1 38 4.1 0.1 4.9 4 1 1 5 5 5 0 DNA directed RNA polymerase, 7 kDa subunit IBR PF01485.21 KFP04396.1 - 6.5 7.1 23.4 11 6.3 2.1 3.7 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain zf-C2H2_7 PF15269.6 KFP04396.1 - 8.4 6.6 12.9 3.7 7.7 0.5 3.2 2 1 1 3 3 3 0 Zinc-finger Ank PF00023.30 KFP04398.1 - 2.1e-28 97.5 1.5 3.4e-06 27.2 0.0 5.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 KFP04398.1 - 7.2e-28 96.6 3.7 3.1e-09 37.2 0.1 4.7 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP04398.1 - 7.6e-26 90.5 0.6 3.3e-12 46.8 0.7 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP04398.1 - 3.1e-23 79.3 1.3 0.00013 22.1 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KFP04398.1 - 2e-19 69.4 3.0 5.8e-07 29.7 0.2 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFP04398.1 - 1.8e-10 41.0 2.1 3.3e-10 40.2 2.1 1.5 1 0 0 1 1 1 1 SOCS box DUF1356 PF07092.12 KFP04399.1 - 3.5e-67 226.1 5.0 3.8e-67 225.9 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) LEA_2 PF03168.13 KFP04399.1 - 0.00067 20.2 0.3 0.00099 19.6 0.3 1.2 1 0 0 1 1 1 1 Late embryogenesis abundant protein COLFI PF01410.18 KFP04400.1 - 1.1e-55 188.4 0.0 1.2e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Plasmodium_HRP PF05403.11 KFP04401.1 - 0.58 9.9 16.3 6.1 6.6 7.1 2.0 1 1 1 2 2 2 0 Plasmodium histidine-rich protein (HRPII/III) RVT_1 PF00078.27 KFP04402.1 - 1.6e-16 60.5 0.0 2.3e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) adh_short PF00106.25 KFP04403.1 - 1.6e-19 70.2 0.0 3.8e-19 68.9 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP04403.1 - 6.6e-15 55.3 0.0 1e-14 54.7 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PRY PF13765.6 KFP04405.1 - 2.9e-19 68.4 0.1 4.4e-19 67.8 0.1 1.3 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.28 KFP04405.1 - 6.9e-06 26.2 0.0 7.7e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 SPRY domain zf-H2C2_2 PF13465.6 KFP04406.1 - 4.6e-43 143.8 61.9 8.5e-09 35.5 1.9 9.3 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFP04406.1 - 8.5e-37 123.6 61.1 1.5e-06 28.4 3.7 8.1 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP04406.1 - 2.9e-32 108.5 58.3 0.00016 22.2 3.8 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFP04406.1 - 6.4e-24 83.4 57.3 7.1e-05 22.7 1.2 8.1 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP04406.1 - 3.5e-13 49.5 15.2 0.029 14.7 0.0 7.9 8 0 0 8 8 8 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFP04406.1 - 1.6e-10 40.5 48.5 0.0068 16.1 1.4 7.3 7 0 0 7 7 7 6 zinc-finger C2H2-type zf_UBZ PF18439.1 KFP04406.1 - 2.7e-09 36.5 25.7 0.72 9.5 0.1 8.1 8 0 0 8 8 8 3 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFP04406.1 - 9.8e-08 32.0 32.4 0.018 15.2 0.8 5.7 3 1 3 6 6 6 5 Zinc ribbon domain zf-Di19 PF05605.12 KFP04406.1 - 8.8e-06 25.9 31.1 0.031 14.6 1.9 5.7 3 3 2 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_15 PF17032.5 KFP04406.1 - 2.4e-05 25.0 17.1 0.17 12.7 0.8 4.2 4 0 0 4 4 4 2 zinc-ribbon family HypA PF01155.19 KFP04406.1 - 0.00033 20.6 19.1 0.25 11.4 0.1 4.3 1 1 2 4 4 4 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA HalOD2 PF18547.1 KFP04406.1 - 0.0035 17.2 0.3 0.0035 17.2 0.3 5.9 6 1 0 6 6 6 1 Halobacterial output domain 2 DUF3268 PF11672.8 KFP04406.1 - 0.0043 17.4 13.9 0.072 13.4 0.3 3.7 3 1 1 4 4 4 2 zinc-finger-containing domain C1_1 PF00130.22 KFP04406.1 - 0.016 15.0 24.2 20 5.2 1.3 6.1 1 1 5 6 6 6 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_4 PF07975.12 KFP04406.1 - 0.02 15.1 22.5 0.083 13.1 0.3 5.0 3 3 2 5 5 5 0 TFIIH C1-like domain zf-C2H2_8 PF15909.5 KFP04406.1 - 0.021 15.1 24.5 0.22 11.9 3.1 4.2 1 1 2 3 3 3 0 C2H2-type zinc ribbon OSTMP1 PF09777.9 KFP04406.1 - 0.026 13.9 1.5 0.046 13.1 0.8 1.8 1 1 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor FYDLN_acid PF09538.10 KFP04406.1 - 0.031 15.0 21.4 4.4 8.0 0.1 7.2 3 2 4 7 7 7 0 Protein of unknown function (FYDLN_acid) zf-ribbon_3 PF13248.6 KFP04406.1 - 0.031 13.7 0.1 0.031 13.7 0.1 7.6 8 0 0 8 8 8 0 zinc-ribbon domain Trm112p PF03966.16 KFP04406.1 - 0.041 14.5 0.2 0.041 14.5 0.2 3.4 4 1 0 4 4 3 0 Trm112p-like protein TerY_C PF15616.6 KFP04406.1 - 0.048 13.8 0.1 0.048 13.8 0.1 3.9 2 1 3 5 5 5 0 TerY-C metal binding domain Zn_ribbon_SprT PF17283.2 KFP04406.1 - 0.056 13.4 36.6 0.075 12.9 0.7 6.4 4 3 2 6 6 6 0 SprT-like zinc ribbon domain LIM PF00412.22 KFP04406.1 - 0.063 13.5 24.3 0.51 10.6 0.2 5.6 3 3 1 4 4 4 0 LIM domain BDHCT_assoc PF16204.5 KFP04406.1 - 0.07 12.8 0.4 3.2 7.4 0.1 2.2 1 1 2 3 3 3 0 BDHCT-box associated domain on Bloom syndrome protein Ogr_Delta PF04606.12 KFP04406.1 - 0.086 12.8 0.9 0.086 12.8 0.9 6.3 5 2 1 7 7 7 0 Ogr/Delta-like zinc finger zf-RING_7 PF02591.15 KFP04406.1 - 0.11 12.6 0.2 0.11 12.6 0.2 6.1 7 0 0 7 7 7 0 C4-type zinc ribbon domain zf-met PF12874.7 KFP04406.1 - 0.2 12.1 38.2 1.6 9.2 0.2 7.8 8 0 0 8 8 8 0 Zinc-finger of C2H2 type CpXC PF14353.6 KFP04406.1 - 0.27 11.3 29.1 1.7 8.7 0.1 7.5 4 3 4 8 8 8 0 CpXC protein zf-LYAR PF08790.11 KFP04406.1 - 0.34 10.8 23.8 2.1 8.3 0.2 7.0 8 0 0 8 8 7 0 LYAR-type C2HC zinc finger zf-C2HC_2 PF13913.6 KFP04406.1 - 0.41 10.6 55.4 0.45 10.5 1.5 8.9 9 1 0 9 9 8 0 zinc-finger of a C2HC-type zinc_ribbon_9 PF14369.6 KFP04406.1 - 0.45 10.8 0.1 0.45 10.8 0.1 7.0 7 1 1 8 8 7 0 zinc-ribbon zf-C2H2_2 PF12756.7 KFP04406.1 - 0.55 10.6 27.3 12 6.3 0.4 7.3 2 2 4 7 7 7 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 KFP04406.1 - 1.2 8.8 19.2 2.2 8.0 0.3 5.2 2 1 4 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-BED PF02892.15 KFP04406.1 - 2.2 8.4 37.8 0.13 12.3 1.2 7.0 2 1 3 5 5 5 0 BED zinc finger Mut7-C PF01927.16 KFP04406.1 - 3 7.9 20.5 0.83 9.7 1.7 5.3 2 2 2 4 4 4 0 Mut7-C RNAse domain GAGA PF09237.11 KFP04406.1 - 3.8 7.4 26.8 1.2 9.0 1.1 5.4 3 2 3 6 6 6 0 GAGA factor ADK_lid PF05191.14 KFP04406.1 - 5.1 7.2 26.6 0.86 9.6 0.2 5.7 5 2 1 6 6 6 0 Adenylate kinase, active site lid zf-MYST PF17772.1 KFP04406.1 - 7.1 6.3 16.4 23 4.7 0.1 5.6 5 2 2 7 7 6 0 MYST family zinc finger domain Membr_traf_MHD PF10540.9 KFP04407.1 - 6.6e-55 185.4 3.5 1.8e-54 184.0 3.5 1.8 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KFP04407.1 - 8.3e-54 180.2 4.8 2.2e-26 92.1 0.3 4.1 4 0 0 4 4 4 3 C2 domain DUF1041 PF06292.17 KFP04407.1 - 8.6e-37 125.8 3.3 3.1e-36 124.0 0.1 3.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1041) C1_1 PF00130.22 KFP04407.1 - 2.8e-11 43.1 6.1 7.7e-11 41.7 6.1 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) CTF_NFI PF00859.18 KFP04408.1 - 2.4e-138 461.0 24.0 2.9e-138 460.7 24.0 1.1 1 0 0 1 1 1 1 CTF/NF-I family transcription modulation region NfI_DNAbd_pre-N PF10524.9 KFP04408.1 - 1.2e-25 89.0 4.3 2.1e-25 88.3 4.3 1.4 1 0 0 1 1 1 1 Nuclear factor I protein pre-N-terminus MH1 PF03165.16 KFP04408.1 - 4.2e-12 46.2 0.5 7.9e-12 45.3 0.5 1.5 1 0 0 1 1 1 1 MH1 domain HEAT_2 PF13646.6 KFP04409.1 - 6.5e-22 77.7 0.1 1.6e-13 50.9 0.0 2.0 1 1 1 2 2 2 2 HEAT repeats HEAT_PBS PF03130.16 KFP04409.1 - 1.1e-14 53.5 0.7 6.2e-06 26.4 0.0 3.3 3 0 0 3 3 3 3 PBS lyase HEAT-like repeat HEAT PF02985.22 KFP04409.1 - 0.0017 18.5 0.3 0.047 14.0 0.0 3.0 4 0 0 4 4 4 1 HEAT repeat Arm PF00514.23 KFP04409.1 - 0.032 14.3 0.1 0.1 12.6 0.0 2.0 2 1 0 2 2 2 0 Armadillo/beta-catenin-like repeat DDE_Tnp_4 PF13359.6 KFP04410.1 - 6.4e-30 103.9 0.0 9.1e-30 103.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFP04410.1 - 7.6e-13 48.5 0.0 1.1e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein HTH_Tnp_4 PF13613.6 KFP04410.1 - 0.00014 21.5 0.0 0.0003 20.4 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KFP04410.1 - 0.095 12.3 0.2 0.21 11.2 0.2 1.7 1 1 0 1 1 1 0 Transposase DDE domain WD40 PF00400.32 KFP04411.1 - 1.4e-15 57.4 6.0 0.00097 19.9 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP04411.1 - 3.5e-10 40.0 1.4 0.00015 22.0 0.1 3.4 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP04411.1 - 0.00012 22.0 0.0 0.058 13.3 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KFP04411.1 - 0.005 15.5 0.1 0.011 14.4 0.1 1.5 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFP04411.1 - 0.013 14.4 0.0 0.12 11.3 0.0 2.3 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MFS_2 PF13347.6 KFP04412.1 - 1.3e-14 53.6 16.1 1.3e-14 53.6 16.1 1.9 2 1 0 2 2 2 1 MFS/sugar transport protein TMIE PF16038.5 KFP04412.1 - 2.5 8.0 6.1 5.2 7.0 6.1 1.4 1 0 0 1 1 1 0 TMIE protein HMG_box PF00505.19 KFP04413.1 - 2.3e-20 72.8 1.1 7e-20 71.2 1.1 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP04413.1 - 9e-12 45.4 0.4 9e-12 45.4 0.4 2.2 3 0 0 3 3 3 1 HMG-box domain LMBR1 PF04791.16 KFP04413.1 - 0.0082 15.1 0.7 0.0097 14.9 0.7 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein PI3K_P85_iSH2 PF16454.5 KFP04413.1 - 0.087 12.4 20.1 0.027 14.1 6.5 2.3 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF812 PF05667.11 KFP04413.1 - 0.2 10.5 13.9 0.37 9.6 13.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Leu_zip PF15294.6 KFP04413.1 - 0.38 10.2 13.2 0.052 13.1 5.9 2.1 2 0 0 2 2 2 0 Leucine zipper DUF724 PF05266.14 KFP04413.1 - 1.2 8.9 12.8 0.11 12.3 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) AAA_23 PF13476.6 KFP04413.1 - 1.8 9.0 17.4 5.3 7.5 3.0 2.1 2 0 0 2 2 2 0 AAA domain APG6_N PF17675.1 KFP04413.1 - 4.6 7.8 27.1 9.5 6.8 4.8 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region NEMP PF10225.9 KFP04413.1 - 9.4 5.8 10.0 0.33 10.6 0.5 2.1 1 1 0 2 2 2 0 NEMP family PDZ PF00595.24 KFP04414.1 - 1.8e-07 31.4 0.0 2.8e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP04414.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 PDZ domain PIP5K PF01504.18 KFP04415.1 - 3.5e-93 311.8 0.0 4.3e-93 311.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Toxin_33 PF08121.11 KFP04415.1 - 0.2 11.5 0.8 0.39 10.6 0.8 1.5 1 0 0 1 1 1 0 Waglerin family PID PF00640.23 KFP04416.1 - 1.2e-43 148.5 0.1 1.9e-43 147.8 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.24 KFP04416.1 - 6e-29 100.2 1.2 5.3e-14 52.3 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFP04416.1 - 1.4e-15 56.9 0.7 1.6e-07 31.1 0.1 2.7 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 KFP04416.1 - 3.3e-06 27.3 0.0 0.00052 20.3 0.0 2.4 2 0 0 2 2 2 1 PDZ domain DUF993 PF06187.11 KFP04416.1 - 0.0068 15.3 0.1 0.011 14.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF993) NRho PF16733.5 KFP04416.1 - 0.044 13.8 0.6 0.11 12.6 0.1 1.8 2 0 0 2 2 2 0 Rhomboid N-terminal domain DUF1435 PF07256.12 KFP04416.1 - 0.35 11.0 0.7 0.66 10.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) Ribosomal_L37 PF08561.10 KFP04417.1 - 1.3e-10 41.9 0.1 1.8e-10 41.4 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 Homeodomain PF00046.29 KFP04418.1 - 1.9e-24 85.3 4.7 3e-24 84.6 4.7 1.3 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 KFP04418.1 - 2e-10 40.1 1.4 4.3e-10 39.1 1.4 1.6 1 0 0 1 1 1 1 OAR domain T6SS_TssF PF05947.12 KFP04418.1 - 0.0019 16.8 0.0 0.0022 16.6 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF Homeobox_KN PF05920.11 KFP04418.1 - 0.055 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Homeobox KN domain Pkinase_Tyr PF07714.17 KFP04419.1 - 1.4e-88 296.6 0.0 1.8e-88 296.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP04419.1 - 2.4e-47 161.5 0.0 3.7e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFP04419.1 - 9.3e-20 70.5 0.0 2e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFP04419.1 - 7.3e-10 38.3 0.0 1.4e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP04419.1 - 4.1e-06 26.4 0.1 8e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFP04419.1 - 4.4e-06 26.4 0.0 1.3e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain APH PF01636.23 KFP04419.1 - 0.0018 18.3 0.0 0.0068 16.3 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFP04419.1 - 0.0064 15.3 0.0 0.0099 14.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KFP04419.1 - 0.0071 16.0 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KFP04419.1 - 0.014 14.4 0.1 0.025 13.5 0.1 1.4 1 1 0 1 1 1 0 Haspin like kinase domain SH3_3 PF08239.11 KFP04419.1 - 0.032 14.5 0.2 0.068 13.5 0.2 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain Kinase-like PF14531.6 KFP04419.1 - 0.064 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like SAS-6_N PF16531.5 KFP04419.1 - 0.16 12.6 0.0 0.35 11.5 0.0 1.5 1 0 0 1 1 1 0 Centriolar protein SAS N-terminal RRM_1 PF00076.22 KFP04420.1 - 1.9e-62 207.0 0.1 1.3e-19 69.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP04420.1 - 2.5e-11 43.2 0.0 0.0014 18.2 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KFP04420.1 - 1.2e-05 25.4 0.0 0.04 14.1 0.0 2.9 3 0 0 3 3 3 2 BRCA1-associated protein 2 RRM_3 PF08777.11 KFP04420.1 - 0.00042 20.3 0.0 0.17 11.9 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif RRM_occluded PF16842.5 KFP04420.1 - 0.0022 17.8 0.0 1.2 9.0 0.0 2.9 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 KFP04420.1 - 0.0042 17.2 0.0 1.5 9.0 0.0 3.3 3 0 0 3 3 3 1 RNA recognition motif E2 PF08199.11 KFP04420.1 - 0.1 12.5 0.0 0.35 10.8 0.0 1.9 1 0 0 1 1 1 0 Bacteriophage E2-like protein SET_assoc PF11767.8 KFP04420.1 - 0.12 12.1 0.0 5.9 6.6 0.0 2.6 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated SDF PF00375.18 KFP04421.1 - 4.2e-125 417.8 27.0 4.7e-125 417.6 27.0 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family hSH3 PF14603.6 KFP04422.1 - 3.9e-26 91.3 0.0 4.4e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Helically-extended SH3 domain SH3_2 PF07653.17 KFP04422.1 - 0.00019 21.0 0.0 0.00027 20.6 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFP04422.1 - 0.037 13.9 0.0 0.053 13.4 0.0 1.2 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.28 KFP04422.1 - 0.056 13.1 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 SH3 domain Myosin_head PF00063.21 KFP04423.1 - 3.2e-249 828.7 0.0 3.8e-249 828.5 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 KFP04423.1 - 1.6e-15 55.4 25.8 0.00034 20.2 0.8 4.8 4 0 0 4 4 4 4 IQ calmodulin-binding motif AAA_16 PF13191.6 KFP04423.1 - 0.015 15.7 0.9 0.059 13.8 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 KFP04423.1 - 0.048 13.9 0.2 0.18 12.1 0.2 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KFP04423.1 - 0.11 11.8 0.5 0.22 10.8 0.1 1.6 2 0 0 2 2 2 0 Zeta toxin MBD_C PF14048.6 KFP04424.1 - 6.5e-36 122.9 0.4 1.2e-35 122.1 0.1 1.6 2 0 0 2 2 2 1 C-terminal domain of methyl-CpG binding protein 2 and 3 MBDa PF16564.5 KFP04424.1 - 6.8e-31 106.3 0.8 1.4e-30 105.3 0.8 1.5 1 0 0 1 1 1 1 p55-binding region of Methyl-CpG-binding domain proteins MBD MBD PF01429.19 KFP04424.1 - 3e-08 33.2 0.1 0.00041 20.0 0.0 2.3 2 0 0 2 2 2 2 Methyl-CpG binding domain RasGAP PF00616.19 KFP04424.1 - 0.0015 18.3 0.0 0.0024 17.6 0.0 1.4 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase NUMOD1 PF07453.13 KFP04424.1 - 0.19 12.0 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 NUMOD1 domain TLV_coat PF00429.19 KFP04425.1 - 4.6e-111 372.2 0.4 5.2e-111 372.1 0.4 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) SlyX PF04102.12 KFP04425.1 - 0.031 14.9 0.1 0.031 14.9 0.1 2.5 1 1 2 3 3 3 0 SlyX UCR_6-4kD PF08997.10 KFP04426.1 - 4e-28 97.1 2.5 4.3e-28 97.0 2.5 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein QCR10 PF09796.9 KFP04426.1 - 2.6e-05 24.2 1.8 0.0002 21.4 1.8 1.9 1 1 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) HLH PF00010.26 KFP04427.1 - 2.1e-09 37.2 2.8 5.6e-09 35.8 2.8 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CDC45 PF02724.14 KFP04427.1 - 0.18 10.1 8.2 0.24 9.7 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Homeodomain PF00046.29 KFP04428.1 - 1.7e-11 43.8 1.4 2.4e-11 43.3 1.4 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP04428.1 - 2.2e-05 24.2 0.6 4.5e-05 23.3 0.1 1.7 2 0 0 2 2 2 1 Homeobox KN domain PhoLip_ATPase_C PF16212.5 KFP04429.1 - 5.2e-68 229.5 19.0 5.2e-68 229.5 19.0 3.0 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFP04429.1 - 2.3e-25 88.0 5.5 7.4e-25 86.4 5.5 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KFP04429.1 - 1.2e-15 57.3 0.1 7.7e-14 51.6 0.0 3.1 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFP04429.1 - 5.5e-12 46.4 3.5 1.5e-06 28.6 0.6 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFP04429.1 - 2.1e-05 24.1 4.1 3.8e-05 23.3 0.1 2.9 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFP04429.1 - 0.00017 21.4 0.0 0.00034 20.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_4 PF12146.8 KFP04430.1 - 4.7e-14 52.2 0.0 1.3e-07 31.2 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFP04430.1 - 5.2e-08 32.8 0.1 0.0022 17.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFP04430.1 - 5.5e-07 29.3 0.0 5.7e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KFP04430.1 - 2.3e-06 28.4 0.0 0.00018 22.2 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF818 PF05677.12 KFP04430.1 - 0.0014 17.7 0.1 0.0021 17.1 0.1 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DLH PF01738.18 KFP04430.1 - 0.0015 18.2 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family UPF0227 PF05728.12 KFP04430.1 - 0.0019 18.2 0.0 0.018 15.0 0.0 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) Asp2 PF16929.5 KFP04430.1 - 0.004 16.2 0.0 0.0056 15.7 0.0 1.1 1 0 0 1 1 1 1 Accessory Sec system GspB-transporter FSH1 PF03959.13 KFP04430.1 - 0.0061 16.2 0.0 0.0095 15.6 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 KFP04430.1 - 0.016 15.0 0.0 0.029 14.1 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KFP04430.1 - 0.018 14.8 0.0 0.14 11.9 0.0 2.1 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase zf-A20 PF01754.16 KFP04431.1 - 6.9e-13 48.3 6.9 2.4e-12 46.5 6.9 2.0 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.16 KFP04431.1 - 3.2e-09 36.8 6.8 3.2e-09 36.8 6.8 2.3 2 0 0 2 2 2 1 AN1-like Zinc finger CTU2 PF10288.9 KFP04431.1 - 0.8 10.0 8.2 4.5 7.5 8.2 2.2 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-C4 PF00105.18 KFP04432.1 - 2.1e-33 114.6 13.6 4.3e-33 113.6 13.6 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) SCAMP PF04144.13 KFP04433.1 - 5.3e-68 228.7 23.3 6e-68 228.5 23.3 1.0 1 0 0 1 1 1 1 SCAMP family DUF4051 PF13260.6 KFP04433.1 - 0.35 10.6 0.0 0.35 10.6 0.0 2.6 4 0 0 4 4 4 0 Protein of unknown function (DUF4051) Pkinase PF00069.25 KFP04434.1 - 2.4e-25 89.4 0.0 3.1e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain CK1gamma_C PF12605.8 KFP04434.1 - 6.6e-25 88.2 3.9 1.3e-24 87.3 3.9 1.5 1 0 0 1 1 1 1 Casein kinase 1 gamma C terminal Pkinase_Tyr PF07714.17 KFP04434.1 - 1.4e-14 54.0 0.0 1.8e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP04434.1 - 7.3e-08 31.6 0.1 9.7e-08 31.2 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase PIP49_C PF12260.8 KFP04434.1 - 0.049 13.3 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 PHR PF08005.12 KFP04435.1 - 5e-54 183.1 1.1 7.9e-54 182.4 1.1 1.3 1 0 0 1 1 1 1 PHR domain BTB PF00651.31 KFP04435.1 - 6.8e-22 77.8 0.4 5.8e-20 71.6 0.0 2.8 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.15 KFP04435.1 - 2.5e-10 40.3 0.8 6.5e-09 35.8 0.2 3.0 1 1 2 3 3 3 1 BTB And C-terminal Kelch DUF4082 PF13313.6 KFP04435.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) Pkinase PF00069.25 KFP04436.1 - 1.8e-48 165.2 0.0 2.4e-47 161.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP04436.1 - 5.2e-17 62.0 0.0 2e-16 60.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFP04436.1 - 2.8e-05 23.6 0.1 5.2e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFP04436.1 - 0.0025 16.6 0.0 0.0042 15.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase zf-RRN7 PF11781.8 KFP04436.1 - 0.0099 15.5 0.1 0.023 14.4 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 FTA2 PF13095.6 KFP04436.1 - 0.027 14.1 0.0 2.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFP04436.1 - 0.078 12.9 0.2 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Mob1_phocein PF03637.17 KFP04437.1 - 6.6e-83 276.8 0.3 7.5e-83 276.6 0.3 1.0 1 0 0 1 1 1 1 Mob1/phocein family DOT1 PF08123.13 KFP04438.1 - 5e-83 277.7 0.4 1.4e-82 276.2 0.0 1.9 2 0 0 2 2 2 1 Histone methylation protein DOT1 DUF2000 PF09391.10 KFP04438.1 - 0.68 9.9 2.4 20 5.1 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2000) SF3A2 PF16835.5 KFP04439.1 - 2.9e-40 136.5 0.2 4.9e-40 135.8 0.2 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KFP04439.1 - 3.3e-07 30.5 2.0 3.3e-07 30.5 2.0 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 KFP04439.1 - 0.004 17.1 0.1 0.0066 16.4 0.1 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 KFP04439.1 - 0.051 13.1 3.2 0.094 12.3 3.2 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like LPD24 PF18839.1 KFP04439.1 - 0.22 11.8 0.7 28 5.0 0.0 2.7 3 0 0 3 3 3 0 Large polyvalent protein associated domain 24 zf-C2H2_jaz PF12171.8 KFP04439.1 - 4.9 7.6 6.7 9.9 6.6 5.1 2.3 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding AMH_N PF04709.12 KFP04441.1 - 2.7e-73 247.2 1.3 5.5e-59 200.0 0.2 2.1 1 1 1 2 2 2 2 Anti-Mullerian hormone, N terminal region TGF_beta PF00019.20 KFP04441.1 - 3e-17 63.5 0.5 5.3e-17 62.7 0.5 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain MRP-L20 PF12824.7 KFP04441.1 - 0.48 10.6 2.9 0.92 9.7 2.9 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 JSRP PF15312.6 KFP04442.1 - 1e-10 41.4 2.8 1e-09 38.2 2.8 2.5 1 1 0 1 1 1 1 Junctional sarcoplasmic reticulum protein RXT2_N PF08595.11 KFP04442.1 - 0.09 12.8 0.2 0.16 12.0 0.2 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Pkinase PF00069.25 KFP04443.1 - 0.00094 18.6 0.0 0.34 10.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFP04443.1 - 0.088 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase LRR_8 PF13855.6 KFP04444.1 - 2.3e-59 197.0 71.2 1.2e-12 47.4 3.2 6.0 1 1 8 9 9 9 9 Leucine rich repeat LRR_5 PF13306.6 KFP04444.1 - 5.3e-27 94.3 0.6 7.6e-12 45.3 0.1 2.6 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFP04444.1 - 2.3e-17 62.8 29.6 9.9e-06 25.8 2.1 7.1 4 2 1 7 7 7 6 Leucine Rich repeats (2 copies) I-set PF07679.16 KFP04444.1 - 4.6e-17 61.9 0.0 7.2e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP04444.1 - 1.5e-14 54.3 0.0 3.4e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP04444.1 - 4.7e-11 42.7 0.1 9.9e-11 41.7 0.0 1.6 2 0 0 2 2 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP04444.1 - 9.2e-08 32.3 0.0 1.8e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.33 KFP04444.1 - 3.8e-06 26.7 31.8 0.38 11.5 0.0 10.8 12 0 0 12 12 11 2 Leucine Rich Repeat LRRNT PF01462.18 KFP04444.1 - 3.6e-05 23.3 4.1 3.6e-05 23.3 4.1 3.0 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain V-set PF07686.17 KFP04444.1 - 0.00096 19.3 0.2 0.05 13.8 0.1 2.6 2 1 0 2 2 2 1 Immunoglobulin V-set domain LRR_9 PF14580.6 KFP04444.1 - 0.01 15.4 11.5 0.13 11.8 4.2 2.9 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 KFP04444.1 - 0.012 15.6 23.5 1.5 9.0 0.0 8.4 10 0 0 10 10 10 0 Leucine Rich repeat Ig_6 PF18452.1 KFP04444.1 - 0.021 14.4 0.0 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain LRRCT PF01463.24 KFP04444.1 - 0.032 14.8 2.1 0.26 11.9 0.2 3.6 3 0 0 3 3 3 0 Leucine rich repeat C-terminal domain C2-set_2 PF08205.12 KFP04444.1 - 0.056 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain CUB PF00431.20 KFP04446.1 - 7.2e-13 48.8 0.0 7.8e-13 48.7 0.0 1.0 1 0 0 1 1 1 1 CUB domain TFIID_20kDa PF03847.13 KFP04447.1 - 3.5e-36 123.5 2.8 4.9e-36 123.1 2.8 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KFP04447.1 - 6.6e-06 26.3 0.2 1e-05 25.7 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFP04447.1 - 3.5e-05 24.2 1.2 3.6e-05 24.1 0.1 1.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KFP04447.1 - 9.7e-05 22.4 0.2 0.0002 21.4 0.1 1.6 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KFP04447.1 - 0.0048 17.0 0.1 0.0081 16.3 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF4 PF05236.14 KFP04447.1 - 0.01 15.6 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Ras PF00071.22 KFP04448.1 - 3.4e-26 91.8 0.0 4.1e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP04448.1 - 3.8e-05 23.9 0.0 0.0001 22.5 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP04448.1 - 0.15 11.5 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family Trnau1ap PF17654.1 KFP04449.1 - 3.3e-42 143.5 20.3 4.4e-42 143.1 20.3 1.2 1 0 0 1 1 1 1 Selenocysteine tRNA 1 associated proteins RRM_1 PF00076.22 KFP04449.1 - 5e-13 48.7 0.0 7.7e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GDP_Man_Dehyd PF16363.5 KFP04450.1 - 3.7e-58 197.5 0.0 4.4e-58 197.3 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFP04450.1 - 5.1e-51 173.5 0.0 6.2e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFP04450.1 - 5.1e-19 68.3 0.0 8.2e-17 61.1 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KFP04450.1 - 1.5e-12 47.2 0.0 3e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KFP04450.1 - 5.5e-12 45.4 0.0 2.9e-11 43.1 0.0 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KFP04450.1 - 7.8e-07 29.2 0.0 2e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KFP04450.1 - 1.6e-06 27.5 0.0 0.00012 21.3 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KFP04450.1 - 2.3e-05 23.9 0.0 0.0001 21.8 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 KFP04450.1 - 2.6e-05 23.9 0.4 0.033 13.7 0.1 2.5 2 1 0 2 2 2 2 NmrA-like family KR PF08659.10 KFP04450.1 - 8.9e-05 22.5 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 KR domain L27 PF02828.16 KFP04450.1 - 0.13 12.1 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 L27 domain Abhydrolase_2 PF02230.16 KFP04451.1 - 4.3e-88 294.7 0.0 4.8e-88 294.6 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KFP04451.1 - 3.2e-07 30.4 0.0 5.1e-06 26.5 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFP04451.1 - 2.4e-06 27.0 0.0 0.023 14.0 0.0 2.9 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFP04451.1 - 5.1e-06 27.2 0.0 6.4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KFP04451.1 - 6.5e-05 22.6 0.0 9.7e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KFP04451.1 - 0.00018 21.2 0.3 0.0095 15.6 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 KFP04451.1 - 0.00051 19.8 0.0 0.0055 16.4 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KFP04451.1 - 0.00091 18.8 0.1 0.13 11.7 0.0 2.7 2 1 1 3 3 3 1 Prolyl oligopeptidase family DUF2974 PF11187.8 KFP04451.1 - 0.0029 17.2 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Cutinase PF01083.22 KFP04451.1 - 0.0033 17.4 0.0 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 Cutinase Palm_thioest PF02089.15 KFP04451.1 - 0.2 11.5 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase AXE1 PF05448.12 KFP04451.1 - 0.22 10.2 0.0 0.36 9.5 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) PITH PF06201.13 KFP04452.1 - 2.7e-30 105.6 0.0 3.4e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 PITH domain BLOC1S3 PF15753.5 KFP04452.1 - 0.031 14.4 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Elongin_A PF06881.11 KFP04453.1 - 2.4e-23 82.6 0.2 2.4e-23 82.6 0.2 3.1 3 0 0 3 3 3 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Med26 PF08711.11 KFP04453.1 - 2.2e-13 50.0 0.6 5e-13 48.9 0.6 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Ribosomal_L5 PF00281.19 KFP04454.1 - 7.4e-23 80.7 0.0 5.2e-21 74.7 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 KFP04454.1 - 2.9e-21 75.4 0.0 4.6e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Palm_thioest PF02089.15 KFP04455.1 - 2.7e-82 276.2 0.0 3.1e-82 276.0 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 KFP04455.1 - 0.0083 15.8 0.0 0.038 13.6 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold CAP_N PF01213.19 KFP04456.1 - 1.1e-99 333.9 3.1 4.2e-98 328.7 3.1 2.4 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KFP04456.1 - 7.4e-66 220.6 4.3 1.1e-65 220.0 4.3 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 KFP04456.1 - 0.00013 21.6 2.6 0.00031 20.5 2.6 1.6 1 1 0 1 1 1 1 Tubulin binding cofactor C Bestrophin PF01062.21 KFP04456.1 - 0.054 12.9 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel WH2 PF02205.20 KFP04456.1 - 0.071 13.0 0.1 0.18 11.7 0.1 1.7 1 0 0 1 1 1 0 WH2 motif DUF3114 PF11311.8 KFP04456.1 - 0.14 11.7 0.2 0.25 10.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3114) MFS_2 PF13347.6 KFP04457.1 - 3.6e-109 365.2 22.4 4.1e-108 361.7 22.4 1.9 1 1 0 1 1 1 1 MFS/sugar transport protein Myc_N PF01056.18 KFP04458.1 - 1.9e-36 126.6 4.9 1.1e-27 97.8 0.4 2.5 1 1 1 2 2 2 2 Myc amino-terminal region HLH PF00010.26 KFP04458.1 - 1.9e-13 50.2 0.5 8e-13 48.1 0.4 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF3287 PF11690.8 KFP04458.1 - 0.08 12.7 1.8 0.13 12.0 1.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) IPPT PF01715.17 KFP04459.1 - 2.9e-65 220.3 0.1 3.7e-65 219.9 0.1 1.1 1 0 0 1 1 1 1 IPP transferase Mst1_SARAH PF11629.8 KFP04459.1 - 0.27 11.4 0.1 0.27 11.4 0.1 3.3 3 1 0 3 3 3 0 C terminal SARAH domain of Mst1 SF3a60_bindingd PF12108.8 KFP04459.1 - 3.1 7.8 4.6 0.5 10.3 0.4 1.8 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain DUF1394 PF07159.12 KFP04460.1 - 1.3e-87 293.9 0.6 3e-72 243.4 0.3 1.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1394) EF-hand_7 PF13499.6 KFP04461.1 - 1.7e-24 86.0 5.3 1.6e-15 57.3 0.9 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KFP04461.1 - 1.1e-23 80.9 15.0 9e-08 31.1 0.1 4.8 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KFP04461.1 - 3.7e-22 76.3 6.3 2.1e-07 30.3 0.1 4.8 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 KFP04461.1 - 1.1e-15 56.3 13.9 5.3e-06 25.7 0.1 4.8 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 KFP04461.1 - 3.1e-12 46.1 12.3 2.8e-06 27.1 1.6 4.0 2 1 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFP04461.1 - 9.8e-05 22.6 2.7 1.5 9.2 0.0 3.4 1 1 2 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KFP04461.1 - 0.00014 21.9 0.0 0.023 14.9 0.0 2.5 2 0 0 2 2 2 1 Dockerin type I domain Caleosin PF05042.13 KFP04461.1 - 0.00094 19.1 3.6 0.57 10.1 0.1 3.3 1 1 2 3 3 3 1 Caleosin related protein EF-hand_4 PF12763.7 KFP04461.1 - 0.0046 16.9 7.1 5 7.1 0.6 3.7 2 1 2 4 4 4 2 Cytoskeletal-regulatory complex EF hand p25-alpha PF05517.12 KFP04461.1 - 0.0089 16.2 1.0 0.38 10.9 0.3 2.3 2 0 0 2 2 2 1 p25-alpha YxiJ PF14176.6 KFP04461.1 - 0.072 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 YxiJ-like protein EF-hand_10 PF14788.6 KFP04461.1 - 0.89 9.5 3.6 27 4.7 0.2 3.0 3 0 0 3 3 3 0 EF hand 5-nucleotidase PF06189.12 KFP04462.1 - 3.9e-106 353.9 0.0 3.5e-105 350.7 0.0 1.9 1 1 1 2 2 2 2 5'-nucleotidase Pro_isomerase PF00160.21 KFP04463.1 - 1.1e-16 61.6 0.1 1.6e-16 61.0 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KFP04463.1 - 3e-09 36.5 0.1 6.4e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP04463.1 - 0.0077 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TGFb_propeptide PF00688.18 KFP04464.1 - 1.9e-45 155.5 0.0 2.6e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 KFP04464.1 - 1.1e-37 129.1 2.9 1.8e-37 128.5 2.9 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain WD40 PF00400.32 KFP04465.1 - 2.5e-51 170.5 5.3 4.3e-07 30.5 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP04465.1 - 5.5e-16 58.6 0.1 0.0019 18.5 0.0 5.7 3 3 3 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP04465.1 - 6.2e-09 36.0 0.3 0.0058 16.5 0.1 3.1 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFP04465.1 - 5.7e-06 25.5 0.1 4.4 6.2 0.0 4.6 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KFP04465.1 - 0.00035 19.2 0.1 0.29 9.6 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.8 KFP04465.1 - 0.0011 17.8 5.2 2.6 6.6 0.0 4.1 1 1 3 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KFP04465.1 - 0.0071 15.7 0.0 0.13 11.6 0.0 2.4 1 1 0 1 1 1 1 WD40-like domain PD40 PF07676.12 KFP04465.1 - 0.075 13.0 0.0 0.9 9.6 0.1 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat zf-CCHC_3 PF13917.6 KFP04466.1 - 0.00047 20.1 1.3 0.00047 20.1 1.3 1.8 2 0 0 2 2 2 1 Zinc knuckle SR-25 PF10500.9 KFP04466.1 - 0.018 14.7 31.3 0.027 14.1 31.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_UL55 PF04537.12 KFP04466.1 - 0.082 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL55 protein Rtf2 PF04641.12 KFP04466.1 - 0.091 12.1 19.9 0.12 11.8 19.9 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger LYRIC PF15686.5 KFP04466.1 - 0.52 9.8 24.3 0.65 9.5 24.3 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family DUF913 PF06025.12 KFP04466.1 - 1.8 7.5 7.4 1.9 7.4 7.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4692 PF15763.5 KFP04466.1 - 3.3 8.1 7.3 5 7.6 7.3 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) RR_TM4-6 PF06459.12 KFP04466.1 - 5.4 6.8 14.8 5.6 6.7 14.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 KFP04466.1 - 6.2 5.0 18.6 7.4 4.7 18.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Vpu PF00558.19 KFP04466.1 - 6.5 6.6 5.4 16 5.4 5.4 1.6 1 0 0 1 1 1 0 Vpu protein Hid1 PF12722.7 KFP04466.1 - 9.5 4.2 7.8 9 4.3 7.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Lipocalin PF00061.23 KFP04467.1 - 1.9e-30 106.0 1.9 2e-30 105.9 1.9 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 KFP04467.1 - 5.8e-09 36.0 0.8 6.8e-09 35.7 0.8 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Serinc PF03348.15 KFP04468.1 - 6e-159 529.6 16.8 6.9e-159 529.4 16.8 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Pox_A14 PF05767.12 KFP04468.1 - 0.13 12.4 6.1 0.23 11.6 2.6 2.9 2 1 0 2 2 2 0 Poxvirus virion envelope protein A14 Endothelin PF00322.17 KFP04470.1 - 3.8e-22 77.5 18.1 3.8e-21 74.3 7.2 2.2 2 0 0 2 2 2 2 Endothelin family PXA PF02194.15 KFP04471.1 - 1.2e-30 106.8 0.0 3.7e-30 105.2 0.0 1.9 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 KFP04471.1 - 1.7e-21 76.9 1.3 3.5e-21 75.9 0.1 2.2 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 KFP04471.1 - 1.1e-19 70.5 0.1 2.5e-19 69.3 0.1 1.6 1 0 0 1 1 1 1 PX domain Com_YlbF PF06133.11 KFP04471.1 - 2.6 8.7 5.0 0.71 10.5 0.3 2.4 3 1 0 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA ADAM_spacer1 PF05986.14 KFP04472.1 - 5e-34 116.8 0.0 7.7e-34 116.2 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 ADAM_CR_2 PF17771.1 KFP04472.1 - 4.9e-21 75.0 14.3 4.7e-19 68.7 7.8 4.9 5 0 0 5 5 5 2 ADAM cysteine-rich domain Reprolysin PF01421.19 KFP04472.1 - 1.2e-18 67.8 0.0 1.2e-18 67.8 0.0 1.9 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease TSP_1 PF00090.19 KFP04472.1 - 1.1e-13 51.1 46.4 1.1e-07 32.0 3.7 6.1 7 0 0 7 7 7 3 Thrombospondin type 1 domain Reprolysin_5 PF13688.6 KFP04472.1 - 1.3e-12 48.3 0.0 2.1e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFP04472.1 - 2.4e-08 34.5 0.0 3.7e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFP04472.1 - 0.0015 18.4 0.0 0.0031 17.4 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP04472.1 - 0.18 11.4 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like ADAM_spacer1 PF05986.14 KFP04473.1 - 5.4e-32 110.2 0.0 8e-32 109.7 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 ADAM_CR_2 PF17771.1 KFP04473.1 - 6.9e-22 77.8 12.6 6.6e-20 71.4 6.3 5.1 4 1 1 5 5 5 2 ADAM cysteine-rich domain Reprolysin PF01421.19 KFP04473.1 - 8.2e-22 78.1 0.0 1.2e-21 77.6 0.0 1.2 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease TSP_1 PF00090.19 KFP04473.1 - 1.7e-16 60.1 57.8 8.4e-10 38.7 9.8 6.3 6 0 0 6 6 6 3 Thrombospondin type 1 domain Reprolysin_5 PF13688.6 KFP04473.1 - 2.6e-14 53.8 0.0 2.6e-14 53.8 0.0 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFP04473.1 - 2.6e-12 47.4 0.0 4.9e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFP04473.1 - 1.8e-05 24.7 0.0 3.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP04473.1 - 0.00034 20.3 0.0 0.00054 19.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_Tenascin PF18720.1 KFP04473.1 - 0.18 11.9 5.4 7.4 6.7 0.8 4.1 3 0 0 3 3 3 0 Tenascin EGF domain BTB PF00651.31 KFP04474.1 - 2.1e-29 102.0 0.6 3.6e-29 101.2 0.6 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 KFP04474.1 - 4.7e-19 67.7 24.4 0.00014 22.1 0.4 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP04474.1 - 4e-15 55.2 18.1 0.0022 18.7 0.4 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP04474.1 - 3.9e-13 49.2 23.1 2.8e-06 27.5 0.3 5.0 5 0 0 5 5 5 4 Zinc-finger double domain zf-met PF12874.7 KFP04474.1 - 2.2e-10 40.5 19.4 0.013 15.8 0.3 5.6 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFP04474.1 - 1.1e-08 34.9 24.1 0.0055 16.7 0.1 4.9 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFP04474.1 - 1.3e-07 31.2 20.3 0.012 15.4 0.3 4.8 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFP04474.1 - 2.8e-06 27.4 9.5 0.025 14.9 0.0 4.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFP04474.1 - 0.00014 22.1 13.0 0.3 11.4 2.4 4.1 1 1 3 4 4 4 2 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 KFP04474.1 - 0.0013 18.8 9.7 5.7 7.1 3.0 4.0 2 1 2 4 4 4 2 Zinc ribbon domain zf-C2H2_3rep PF18868.1 KFP04474.1 - 0.011 16.4 6.9 0.36 11.5 0.4 3.8 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_9 PF16293.5 KFP04474.1 - 0.023 14.5 3.3 0.16 11.8 0.1 3.1 3 0 0 3 3 2 0 C2H2 type zinc-finger (1 copy) zf-C2HE PF16278.5 KFP04474.1 - 0.026 15.0 13.7 0.21 12.1 0.0 4.9 3 1 2 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger Glyco_tran_10_N PF17039.5 KFP04474.1 - 0.035 14.5 0.2 0.14 12.6 0.2 2.1 1 0 0 1 1 1 0 Fucosyltransferase, N-terminal zf-H2C2_5 PF13909.6 KFP04474.1 - 0.097 12.5 0.1 0.097 12.5 0.1 3.0 3 0 0 3 3 2 0 C2H2-type zinc-finger domain Zn_Tnp_IS1595 PF12760.7 KFP04474.1 - 0.61 10.1 20.3 0.18 11.8 3.6 3.2 1 1 2 3 3 3 0 Transposase zinc-ribbon domain FYVE PF01363.21 KFP04474.1 - 0.8 9.9 14.5 4.1 7.6 4.5 4.2 1 1 1 2 2 2 0 FYVE zinc finger CpXC PF14353.6 KFP04474.1 - 1 9.4 9.2 43 4.2 6.4 3.6 1 1 2 3 3 3 0 CpXC protein zf-AN1 PF01428.16 KFP04474.1 - 2.3 8.5 12.3 6.1 7.1 0.1 4.5 4 0 0 4 4 4 0 AN1-like Zinc finger C1_1 PF00130.22 KFP04474.1 - 3.1 7.8 9.6 1 9.3 3.8 2.8 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf_UBZ PF18439.1 KFP04474.1 - 3.5 7.3 11.0 2.2 7.9 0.1 4.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger LIM PF00412.22 KFP04474.1 - 4.7 7.5 12.5 3.1 8.1 6.2 3.5 3 1 0 3 3 3 0 LIM domain dUTPase PF00692.19 KFP04475.1 - 4.7e-13 49.0 0.0 6e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 dUTPase 7tm_4 PF13853.6 KFP04476.1 - 1e-30 107.4 8.3 4.3e-22 79.2 2.4 2.0 1 1 1 2 2 2 2 Olfactory receptor 7tm_1 PF00001.21 KFP04476.1 - 1.4e-17 64.0 2.7 1.4e-17 64.0 2.7 2.0 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP04476.1 - 0.00055 19.4 4.4 0.0024 17.3 2.6 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx FEZ PF07763.13 KFP04477.1 - 6.4e-63 212.7 0.7 8.8e-63 212.3 0.7 1.1 1 0 0 1 1 1 1 FEZ-like protein BUD22 PF09073.10 KFP04477.1 - 0.55 9.5 6.8 0.79 9.0 6.8 1.1 1 0 0 1 1 1 0 BUD22 Meis_PKNOX_N PF16493.5 KFP04478.1 - 1.8e-39 133.9 1.4 3.1e-39 133.2 1.4 1.4 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 Homeobox_KN PF05920.11 KFP04478.1 - 8.4e-20 70.4 2.3 2.2e-19 69.1 2.3 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFP04478.1 - 5.5e-08 32.5 0.5 1.3e-07 31.3 0.5 1.6 1 0 0 1 1 1 1 Homeodomain RNA_pol_3_Rpc31 PF11705.8 KFP04478.1 - 0.02 15.2 7.2 0.051 13.8 7.2 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 BSP_II PF05432.11 KFP04478.1 - 0.076 12.7 10.1 0.13 12.0 10.1 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Med4 PF10018.9 KFP04478.1 - 0.1 12.3 9.7 0.44 10.2 0.0 2.4 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 NOA36 PF06524.12 KFP04478.1 - 0.7 9.2 9.5 0.063 12.6 4.9 1.5 2 0 0 2 2 2 0 NOA36 protein TRAP_alpha PF03896.16 KFP04478.1 - 0.79 8.9 6.5 1.5 7.9 6.5 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Paf1 PF03985.13 KFP04478.1 - 0.88 8.5 10.6 1.4 7.9 10.6 1.2 1 0 0 1 1 1 0 Paf1 FAM176 PF14851.6 KFP04478.1 - 1.6 8.4 6.6 6.9 6.3 6.3 2.0 2 0 0 2 2 2 0 FAM176 family TT_ORF2 PF02957.15 KFP04478.1 - 2.2 9.2 12.2 3.6 8.5 4.9 2.6 2 0 0 2 2 2 0 TT viral ORF2 PBP_sp32 PF07222.12 KFP04478.1 - 3.6 7.0 7.4 7.2 6.0 7.4 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DNA_pol_phi PF04931.13 KFP04478.1 - 4.5 5.2 14.1 1.6 6.8 11.4 1.5 2 0 0 2 2 2 0 DNA polymerase phi DUF4746 PF15928.5 KFP04478.1 - 7.9 5.8 11.0 15 4.9 11.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Gemini_mov PF01708.16 KFP04479.1 - 0.013 15.3 0.5 0.02 14.6 0.1 1.6 1 1 0 1 1 1 0 Geminivirus putative movement protein MFS_1 PF07690.16 KFP04480.1 - 1.2e-39 136.2 30.1 1.6e-34 119.4 20.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KFP04480.1 - 0.00018 19.9 1.0 0.0038 15.6 0.0 2.8 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family SecY PF00344.20 KFP04480.1 - 0.24 10.6 5.7 0.2 10.9 2.4 2.2 2 0 0 2 2 2 0 SecY translocase MFS_1_like PF12832.7 KFP04480.1 - 2.1 7.1 19.8 0.3 9.9 10.1 2.5 2 1 0 2 2 2 0 MFS_1 like family Ig_3 PF13927.6 KFP04481.1 - 1.2e-15 57.8 0.0 2.3e-10 40.9 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP04481.1 - 3.4e-14 52.7 0.0 1.1e-07 31.9 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 KFP04481.1 - 6.6e-12 45.6 0.0 1.9e-08 34.5 0.0 2.8 2 1 1 3 3 3 2 Immunoglobulin V-set domain ig PF00047.25 KFP04481.1 - 5e-08 33.0 0.0 0.0046 17.1 0.1 3.0 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP04481.1 - 5.4e-08 33.1 0.0 3.5e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain DUF2434 PF10361.9 KFP04481.1 - 0.25 10.3 0.0 0.36 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) I-set PF07679.16 KFP04482.1 - 7.3e-15 54.8 0.1 2.4e-14 53.1 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP04482.1 - 4.8e-14 52.7 0.1 4.6e-13 49.6 0.0 2.4 3 0 0 3 3 3 1 Immunoglobulin domain fn3 PF00041.21 KFP04482.1 - 5.1e-11 42.8 0.5 0.00022 21.5 0.1 2.5 2 0 0 2 2 2 2 Fibronectin type III domain Ig_2 PF13895.6 KFP04482.1 - 6.2e-09 36.1 0.0 1.1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP04482.1 - 1.2e-07 31.8 0.3 0.00014 22.0 0.0 2.9 3 1 0 3 3 3 1 Immunoglobulin V-set domain ig PF00047.25 KFP04482.1 - 2.7e-07 30.7 0.0 6.5e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.12 KFP04482.1 - 0.00024 21.1 0.0 0.00069 19.6 0.0 1.9 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFP04482.1 - 0.011 15.3 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain Receptor_2B4 PF11465.8 KFP04482.1 - 0.041 14.1 0.0 0.059 13.6 0.0 1.3 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 Herpes_gE PF02480.16 KFP04482.1 - 0.17 10.6 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E I-set PF07679.16 KFP04483.1 - 7.9e-13 48.3 0.0 1.7e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP04483.1 - 1.3e-12 48.1 0.0 4.6e-12 46.4 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain fn3 PF00041.21 KFP04483.1 - 6.9e-11 42.3 0.2 0.00039 20.7 0.0 2.4 2 0 0 2 2 2 2 Fibronectin type III domain ig PF00047.25 KFP04483.1 - 1.7e-06 28.1 0.0 3.2e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP04483.1 - 2.5e-05 24.5 0.0 6.4e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFP04483.1 - 0.00043 20.4 0.0 0.54 10.4 0.0 2.6 1 1 1 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP04483.1 - 0.0029 17.6 0.0 0.0065 16.5 0.0 1.6 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFP04483.1 - 0.048 13.2 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain Ig_5 PF16681.5 KFP04483.1 - 0.068 13.6 0.0 0.17 12.3 0.0 1.6 1 1 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_3 PF13927.6 KFP04485.1 - 3e-14 53.4 0.0 6.1e-10 39.6 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP04485.1 - 2.7e-12 46.7 0.7 6.6e-06 26.2 0.1 2.6 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP04485.1 - 1.1e-11 44.7 0.0 1.5e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 KFP04485.1 - 7e-10 39.1 0.5 0.00069 19.8 0.0 3.1 2 1 1 3 3 3 3 Immunoglobulin V-set domain Ig_2 PF13895.6 KFP04485.1 - 1.3e-09 38.2 0.1 8.1e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 KFP04485.1 - 2.2e-05 23.9 0.0 0.089 12.4 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFP04485.1 - 0.0019 18.2 0.1 0.004 17.2 0.0 1.6 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.8 KFP04485.1 - 0.017 15.4 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 Ig_4 PF16680.5 KFP04485.1 - 0.032 14.5 0.0 0.71 10.2 0.0 2.4 2 1 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain IQ PF00612.27 KFP04486.1 - 7e-06 25.4 0.4 1e-05 24.9 0.4 1.3 1 0 0 1 1 1 1 IQ calmodulin-binding motif RIIa PF02197.17 KFP04487.1 - 1.2e-13 50.5 0.5 1.5e-13 50.2 0.5 1.1 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit SASA PF03629.18 KFP04488.1 - 6.8e-13 48.8 0.0 1.2e-05 25.1 0.0 2.4 2 1 0 2 2 2 2 Carbohydrate esterase, sialic acid-specific acetylesterase Innexin PF00876.18 KFP04489.1 - 3.1e-11 43.2 0.5 1.5e-10 40.9 0.5 1.9 1 1 0 1 1 1 1 Innexin PseudoU_synth_2 PF00849.22 KFP04490.1 - 1e-28 100.4 0.0 1.6e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase PseudoU_synth_1 PF01416.20 KFP04491.1 - 3.6e-34 117.5 0.0 1.2e-31 109.3 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase HYLS1_C PF15311.6 KFP04492.1 - 5.9e-18 65.4 0.4 6.5e-18 65.3 0.4 1.0 1 0 0 1 1 1 1 Hydrolethalus syndrome protein 1 C-terminus Helicase_C PF00271.31 KFP04493.1 - 2.8e-26 92.1 0.2 5.4e-26 91.1 0.2 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFP04493.1 - 3.1e-25 89.0 0.0 5.4e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KFP04493.1 - 0.018 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 KFP04493.1 - 0.1 12.6 0.0 0.28 11.2 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Pox_RNA_pol PF03293.14 KFP04493.1 - 0.12 12.1 0.0 0.42 10.3 0.0 1.9 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Ig_3 PF13927.6 KFP04494.1 - 1.1e-63 211.7 2.1 1.1e-15 58.0 0.1 5.8 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 KFP04494.1 - 1.4e-48 162.9 0.0 3.5e-11 43.0 0.0 6.0 6 0 0 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP04494.1 - 2e-47 159.4 0.2 1.5e-09 38.1 0.0 5.5 4 1 1 5 5 5 5 Immunoglobulin domain fn3 PF00041.21 KFP04494.1 - 4.6e-38 129.4 5.3 5.5e-16 58.7 0.1 3.7 3 0 0 3 3 3 3 Fibronectin type III domain ig PF00047.25 KFP04494.1 - 1.8e-33 114.5 0.1 4.6e-06 26.7 0.0 6.1 5 1 0 5 5 5 5 Immunoglobulin domain V-set PF07686.17 KFP04494.1 - 5.9e-20 71.5 8.5 0.00068 19.8 0.0 8.9 7 3 3 10 10 10 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP04494.1 - 5.2e-08 32.9 2.9 0.057 13.5 0.0 5.4 5 0 0 5 5 5 1 CD80-like C2-set immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFP04494.1 - 6.4e-08 33.1 1.2 0.012 16.1 0.0 3.9 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Ig_6 PF18452.1 KFP04494.1 - 6.5e-08 32.0 0.0 6.1 6.5 0.0 5.4 5 0 0 5 5 5 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFP04494.1 - 6.4e-06 26.1 0.0 2.6 8.2 0.0 4.7 5 0 0 5 5 5 2 Izumo-like Immunoglobulin domain BiPBP_C PF06832.12 KFP04494.1 - 0.00057 19.9 0.1 1.4 9.0 0.0 4.2 4 0 0 4 4 4 1 Penicillin-Binding Protein C-terminus Family Tissue_fac PF01108.17 KFP04494.1 - 0.0019 18.0 0.1 0.071 13.0 0.0 3.1 3 0 0 3 3 3 1 Tissue factor Protocadherin PF08374.11 KFP04494.1 - 0.066 13.2 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Protocadherin EphA2_TM PF14575.6 KFP04494.1 - 0.1 13.5 0.0 0.2 12.5 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TNFR_16_TM PF18422.1 KFP04494.1 - 0.13 12.2 1.7 0.27 11.2 1.7 1.4 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain STT3 PF02516.14 KFP04495.1 - 3.4e-164 547.4 42.9 3.3e-159 530.9 38.3 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.6 KFP04495.1 - 1.1e-06 29.0 15.6 1.1e-06 29.0 15.6 2.7 4 0 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF2985 PF11204.8 KFP04495.1 - 0.28 11.3 7.0 0.36 11.0 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2985) EI24 PF07264.11 KFP04496.1 - 1.5e-18 67.7 19.3 2.4e-18 67.0 18.9 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Herpes_pp85 PF04637.12 KFP04496.1 - 3.6 5.9 7.8 5.6 5.3 7.8 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DAO PF01266.24 KFP04497.1 - 4.7e-19 69.2 0.0 5.7e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase SRP-alpha_N PF04086.13 KFP04498.1 - 1.2e-57 196.1 12.0 1.7e-57 195.6 12.0 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KFP04498.1 - 3.2e-47 160.7 0.4 2.7e-46 157.7 0.4 2.2 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KFP04498.1 - 3.4e-10 40.0 0.2 2.1e-09 37.4 0.1 2.4 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KFP04498.1 - 1.2e-07 31.0 0.0 2.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KFP04498.1 - 0.0084 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KFP04498.1 - 0.0095 16.0 0.2 0.57 10.3 0.0 2.6 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 KFP04498.1 - 0.013 15.7 0.1 0.1 12.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain ArsA_ATPase PF02374.15 KFP04498.1 - 0.024 13.8 0.0 0.71 9.0 0.0 2.5 2 0 0 2 2 2 0 Anion-transporting ATPase Fer4_NifH PF00142.18 KFP04498.1 - 0.048 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_16 PF13191.6 KFP04498.1 - 0.053 13.9 0.0 0.14 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 KFP04498.1 - 0.064 13.2 0.3 0.59 10.0 0.0 2.5 2 1 0 2 2 2 0 NTPase SIR2_2 PF13289.6 KFP04499.1 - 5.4e-23 81.7 0.2 1e-22 80.8 0.1 1.6 2 0 0 2 2 2 1 SIR2-like domain RFC1 PF08519.12 KFP04499.1 - 0.064 13.4 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain TIR_2 PF13676.6 KFP04500.1 - 2.7e-19 69.9 0.0 3.6e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 KFP04500.1 - 2.3e-09 37.3 0.0 2.9e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 TIR domain DcpS_C PF11969.8 KFP04501.1 - 5.4e-33 113.9 0.2 1.2e-32 112.8 0.0 1.6 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 KFP04501.1 - 1.8e-13 51.2 0.1 4.5e-13 50.0 0.0 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DUF2145 PF09916.9 KFP04501.1 - 0.065 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2145) Glyco_transf_29 PF00777.18 KFP04502.1 - 5e-65 219.6 0.0 6.2e-65 219.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Ets PF00178.22 KFP04504.1 - 3.1e-36 123.7 0.4 7.3e-36 122.5 0.4 1.7 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 KFP04504.1 - 1.6e-26 92.1 0.1 3.8e-26 90.9 0.1 1.7 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain IRK_C PF17655.1 KFP04505.1 - 4.9e-71 237.9 0.0 6.7e-71 237.5 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFP04505.1 - 7.9e-59 197.5 3.8 8.1e-59 197.5 2.4 1.8 2 0 0 2 2 2 1 Inward rectifier potassium channel transmembrane domain DUF2182 PF09948.9 KFP04505.1 - 0.033 14.1 1.1 0.08 12.8 0.1 2.0 2 1 1 3 3 3 0 Predicted metal-binding integral membrane protein (DUF2182) CrgA PF06781.12 KFP04505.1 - 0.12 12.5 0.1 0.28 11.3 0.1 1.6 1 0 0 1 1 1 0 Cell division protein CrgA Ion_trans_2 PF07885.16 KFP04505.1 - 0.69 9.9 6.3 2.1 8.4 6.2 1.9 1 1 0 1 1 1 0 Ion channel IRK_C PF17655.1 KFP04506.1 - 8.6e-75 250.1 0.1 1.2e-74 249.7 0.1 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFP04506.1 - 7.2e-58 194.4 2.6 1e-57 193.9 2.6 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 KFP04506.1 - 0.023 14.6 9.3 0.072 13.1 9.3 1.8 1 1 0 1 1 1 0 Ion channel Ion_trans PF00520.31 KFP04506.1 - 0.028 13.6 3.4 0.041 13.1 3.4 1.2 1 0 0 1 1 1 0 Ion transport protein Homeodomain PF00046.29 KFP04507.1 - 2e-21 75.6 3.4 4e-21 74.6 3.4 1.5 1 0 0 1 1 1 1 Homeodomain CCDC53 PF10152.9 KFP04507.1 - 3 8.2 11.2 17 5.8 0.2 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF716 PF04819.12 KFP04508.1 - 2.7e-28 98.3 9.0 5.6e-28 97.3 9.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF716) TnpB_IS66 PF05717.13 KFP04508.1 - 0.092 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 IS66 Orf2 like protein DUF716 PF04819.12 KFP04509.1 - 4.2e-25 88.0 5.3 4.2e-25 88.0 5.3 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF716) APP_E2 PF12925.7 KFP04511.1 - 5.3e-70 235.0 16.3 1.1e-69 233.9 16.3 1.5 1 0 0 1 1 1 1 E2 domain of amyloid precursor protein APP_N PF02177.16 KFP04511.1 - 1.2e-42 144.3 0.5 1.2e-42 144.3 0.5 2.3 2 0 0 2 2 2 1 Amyloid A4 N-terminal heparin-binding APP_Cu_bd PF12924.7 KFP04511.1 - 7.4e-27 93.9 5.7 7.4e-27 93.9 5.7 3.6 3 0 0 3 3 3 1 Copper-binding of amyloid precursor, CuBD APP_amyloid PF10515.9 KFP04511.1 - 7.7e-26 90.4 0.2 4.1e-25 88.0 0.2 2.4 1 0 0 1 1 1 1 Beta-amyloid precursor protein C-terminus Kunitz_BPTI PF00014.23 KFP04511.1 - 3.9e-20 71.8 5.4 3.9e-20 71.8 5.4 2.3 3 0 0 3 3 3 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Insulin_TMD PF17870.1 KFP04511.1 - 0.48 10.5 1.4 0.98 9.5 1.4 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment FNIP_M PF14637.6 KFP04511.1 - 1 9.3 4.0 12 5.8 0.4 2.3 2 0 0 2 2 2 0 Folliculin-interacting protein middle domain Activator-TraM PF11657.8 KFP04511.1 - 1.5 8.6 6.1 3.5 7.4 6.1 1.6 1 0 0 1 1 1 0 Transcriptional activator TraM Tristanin_u2 PF16638.5 KFP04512.1 - 8.6e-49 165.7 5.3 8.6e-49 165.7 5.3 4.1 4 1 0 4 4 2 1 Unstructured region on methyltransferase between zinc-fingers zf-C2H2 PF00096.26 KFP04512.1 - 6.1e-33 111.4 77.2 5.5e-05 23.4 2.5 10.8 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP04512.1 - 5.9e-27 92.0 79.8 0.0046 17.7 1.7 11.0 11 0 0 11 11 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP04512.1 - 5.1e-18 64.6 66.5 0.00047 20.5 0.4 12.2 11 1 0 11 11 11 7 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFP04512.1 - 3.2e-15 55.9 56.8 0.0024 18.1 0.0 10.7 11 0 0 11 11 11 7 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFP04512.1 - 3.4e-08 33.7 47.2 0.15 12.4 10.8 9.3 5 2 1 7 7 7 4 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KFP04512.1 - 4.2e-07 29.8 49.3 0.0032 17.4 0.4 9.0 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KFP04512.1 - 5.7e-06 27.0 29.6 2 9.1 1.0 8.0 6 1 2 8 8 7 4 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 KFP04512.1 - 7.7e-06 26.1 2.6 0.0032 17.8 0.0 9.4 9 0 0 9 9 8 3 Zinc-finger of C2H2 type zf_PR_Knuckle PF18445.1 KFP04512.1 - 8.3e-06 25.5 2.0 8.3e-06 25.5 2.0 3.9 4 0 0 4 4 3 1 PR zinc knuckle motif zf-Di19 PF05605.12 KFP04512.1 - 0.0033 17.7 44.1 0.084 13.2 2.6 7.6 6 1 3 9 9 9 4 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 KFP04512.1 - 0.0083 15.7 40.3 1.1 8.9 0.1 8.9 9 0 0 9 9 9 3 Ubiquitin-Binding Zinc Finger DUF629 PF04780.12 KFP04512.1 - 0.0088 14.6 37.7 0.29 9.6 0.0 7.2 4 2 3 7 7 7 3 Protein of unknown function (DUF629) zf-BED PF02892.15 KFP04512.1 - 0.015 15.3 3.0 0.015 15.3 3.0 7.5 6 2 1 7 7 7 0 BED zinc finger zf_C2H2_ZHX PF18387.1 KFP04512.1 - 0.46 10.2 0.0 0.46 10.2 0.0 7.9 7 1 2 9 9 9 0 Zinc-fingers and homeoboxes C2H2 finger domain Zn_Tnp_IS1595 PF12760.7 KFP04512.1 - 1.4 8.9 26.9 0.096 12.7 2.0 5.7 5 0 0 5 5 5 0 Transposase zinc-ribbon domain Zn-C2H2_12 PF18112.1 KFP04512.1 - 5.9 7.5 19.3 2.8 8.5 0.3 5.4 5 0 0 5 5 5 0 Autophagy receptor zinc finger-C2H2 domain DUF4428 PF14471.6 KFP04512.1 - 6.1 6.9 12.4 0.74 9.8 0.0 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4428) NFRKB_winged PF14465.6 KFP04513.1 - 1.4e-32 111.9 2.7 2.2e-32 111.3 0.9 2.4 2 0 0 2 2 2 1 NFRKB Winged Helix-like ATP-synt_E PF05680.12 KFP04513.1 - 4.6 7.7 6.4 1.6 9.1 1.6 2.5 2 0 0 2 2 2 0 ATP synthase E chain Trypsin PF00089.26 KFP04514.1 - 3.9e-65 219.8 0.1 6.6e-65 219.0 0.1 1.4 1 0 0 1 1 1 1 Trypsin Ldl_recept_a PF00057.18 KFP04514.1 - 1.3e-36 124.5 82.7 1.2e-09 38.2 14.4 5.2 5 0 0 5 5 5 4 Low-density lipoprotein receptor domain class A CUB PF00431.20 KFP04514.1 - 1.7e-36 124.9 0.3 1e-19 70.9 0.4 2.5 2 0 0 2 2 2 2 CUB domain SEA PF01390.20 KFP04514.1 - 2.5e-12 46.8 0.0 5.1e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 SEA domain DUF1986 PF09342.11 KFP04514.1 - 2e-05 24.9 0.1 5.3e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) CUB_2 PF02408.20 KFP04514.1 - 8.3e-05 22.3 2.1 0.00019 21.2 0.9 2.2 2 0 0 2 2 2 1 CUB-like domain IBR PF01485.21 KFP04515.1 - 4e-06 26.9 41.9 0.00016 21.8 9.5 4.1 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain DUF226 PF02890.14 KFP04515.1 - 0.11 12.5 0.8 0.21 11.6 0.8 1.4 1 0 0 1 1 1 0 Borrelia family of unknown function DUF226 Fascin PF06268.13 KFP04516.1 - 3.4e-63 210.8 0.4 2.6e-23 82.3 0.2 3.0 3 0 0 3 3 3 3 Fascin domain FRG1 PF06229.12 KFP04516.1 - 3.7e-12 46.4 1.2 0.0025 17.6 0.0 4.6 2 2 3 5 5 5 4 FRG1-like domain Actin PF00022.19 KFP04517.1 - 1.3e-151 504.9 0.0 4.1e-151 503.2 0.0 1.6 1 1 0 1 1 1 1 Actin F-box PF00646.33 KFP04519.1 - 6.6e-07 29.1 1.6 6.6e-07 29.1 1.6 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KFP04519.1 - 1.9e-06 27.6 1.3 1.9e-06 27.6 1.3 2.6 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 KFP04519.1 - 0.00068 20.0 18.0 0.041 14.3 0.6 6.0 5 2 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFP04519.1 - 0.0081 16.1 16.5 12 6.2 0.7 6.9 6 0 0 6 6 6 2 Leucine Rich repeat Nucleoside_tran PF01733.18 KFP04520.1 - 2.6e-49 168.3 4.2 2.6e-49 168.3 4.2 2.1 2 1 0 2 2 2 1 Nucleoside transporter WD40 PF00400.32 KFP04521.1 - 3.6e-05 24.5 0.0 4 8.5 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP04521.1 - 0.0015 18.7 0.0 0.17 12.2 0.0 3.3 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP04521.1 - 0.063 12.2 0.2 5.6 5.8 0.0 2.3 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 KFP04521.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain HlyIII PF03006.20 KFP04522.1 - 2.6e-18 66.6 18.9 3.3e-18 66.2 18.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related DIL PF01843.19 KFP04523.1 - 1e-22 80.4 2.8 2.3e-22 79.2 2.5 1.7 2 0 0 2 2 2 1 DIL domain RA PF00788.23 KFP04523.1 - 2.7e-17 63.2 0.0 5e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PDZ PF00595.24 KFP04523.1 - 3.6e-11 43.3 0.0 6.4e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP04523.1 - 1.2e-09 37.9 0.0 2.5e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP04523.1 - 0.00028 21.2 0.0 0.00053 20.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain SPG48 PF14764.6 KFP04524.1 - 3.9e-43 146.7 8.6 7.5e-43 145.8 2.1 3.7 4 0 0 4 4 4 1 AP-5 complex subunit, vesicle trafficking FANCF PF11107.8 KFP04524.1 - 0.011 15.0 0.3 0.02 14.1 0.3 1.4 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) TetR_C_30 PF17939.1 KFP04524.1 - 0.081 13.2 0.0 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Forkhead PF00250.18 KFP04525.1 - 1e-41 141.1 0.2 1.7e-41 140.3 0.2 1.4 1 0 0 1 1 1 1 Forkhead domain p450 PF00067.22 KFP04526.1 - 1.3e-125 419.8 0.1 1.5e-125 419.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFP04527.1 - 4.9e-115 384.9 0.4 5.5e-115 384.8 0.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 CbtB PF09489.10 KFP04527.1 - 0.24 11.5 0.3 0.59 10.3 0.3 1.6 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) CARD PF00619.21 KFP04528.1 - 2.6e-21 75.5 0.0 9.3e-21 73.7 0.0 2.1 1 0 0 1 1 1 1 Caspase recruitment domain PDZ PF00595.24 KFP04528.1 - 2.4e-06 27.8 0.0 5.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Guanylate_kin PF00625.21 KFP04528.1 - 1.5e-05 24.8 0.1 1.5e-05 24.8 0.1 2.6 2 0 0 2 2 2 1 Guanylate kinase PDZ_6 PF17820.1 KFP04528.1 - 0.00043 20.1 0.0 0.0019 18.0 0.0 2.2 2 0 0 2 2 2 1 PDZ domain Peptidase_M54 PF07998.11 KFP04529.1 - 7.8e-06 26.0 1.3 9.8e-05 22.4 3.2 1.8 2 0 0 2 2 2 1 Peptidase family M54 Peptidase_M10 PF00413.24 KFP04529.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Matrixin DUF4241 PF14025.6 KFP04529.1 - 0.15 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) HEAT PF02985.22 KFP04530.1 - 1.4e-10 40.5 2.8 0.012 15.8 0.0 6.5 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 KFP04530.1 - 1.9e-05 24.9 0.3 0.0032 17.8 0.0 3.6 4 0 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 KFP04530.1 - 0.0014 19.1 0.0 1.5 9.4 0.0 4.5 4 0 0 4 4 4 1 HEAT-like repeat RTP1_C1 PF10363.9 KFP04530.1 - 0.012 15.8 0.0 0.079 13.1 0.0 2.4 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 KFP04530.1 - 0.041 13.9 0.7 0.99 9.4 0.0 3.4 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 SOGA PF11365.8 KFP04531.1 - 0.0057 17.8 17.6 0.038 15.1 9.0 3.0 2 1 0 2 2 2 1 Protein SOGA DivIC PF04977.15 KFP04531.1 - 0.01 15.6 19.1 0.59 9.9 3.9 3.7 3 1 1 4 4 4 0 Septum formation initiator YabA PF06156.13 KFP04531.1 - 0.013 16.1 22.7 0.098 13.3 2.4 3.4 2 1 1 3 3 3 0 Initiation control protein YabA Cnn_1N PF07989.11 KFP04531.1 - 0.025 14.7 0.4 0.025 14.7 0.4 3.6 2 1 0 2 2 1 0 Centrosomin N-terminal motif 1 SlyX PF04102.12 KFP04531.1 - 0.04 14.5 15.3 0.1 13.2 1.9 3.4 2 1 0 3 3 3 0 SlyX APG6_N PF17675.1 KFP04531.1 - 0.087 13.3 28.9 2.2 8.8 14.2 3.0 1 1 0 2 2 2 0 Apg6 coiled-coil region ADIP PF11559.8 KFP04531.1 - 0.13 12.4 21.8 0.81 9.8 4.7 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Chibby PF14645.6 KFP04531.1 - 0.29 11.6 16.3 0.27 11.7 4.5 2.7 2 1 0 2 2 2 0 Chibby family LPP PF04728.13 KFP04531.1 - 0.41 11.1 8.0 2.4 8.6 0.6 3.5 3 0 0 3 3 3 0 Lipoprotein leucine-zipper betaPIX_CC PF16523.5 KFP04531.1 - 0.42 10.5 16.6 0.035 13.9 1.8 3.1 3 0 0 3 3 3 0 betaPIX coiled coil ATG16 PF08614.11 KFP04531.1 - 0.93 9.7 27.7 3.5 7.8 0.3 3.3 1 1 0 3 3 3 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 KFP04531.1 - 1 9.5 18.8 4.5 7.5 2.2 3.2 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Allexi_40kDa PF05549.11 KFP04531.1 - 1.4 8.3 9.2 0.18 11.3 4.3 1.8 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF5595 PF18077.1 KFP04531.1 - 2.5 8.2 11.4 1.8 8.7 0.2 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF5595) GAS PF13851.6 KFP04531.1 - 3.4 7.0 28.2 0.15 11.4 7.7 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding GIT_CC PF16559.5 KFP04531.1 - 3.9 7.4 12.3 1.7 8.6 2.1 3.4 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor HisKA PF00512.25 KFP04531.1 - 4.2 7.5 8.5 1.4 9.0 0.3 2.9 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain HIP1_clath_bdg PF16515.5 KFP04531.1 - 6.2 7.5 22.4 2.4 8.8 1.7 3.7 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Seryl_tRNA_N PF02403.22 KFP04531.1 - 6.4 7.1 23.5 6.1 7.1 4.8 3.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Prefoldin_2 PF01920.20 KFP04531.1 - 6.9 6.7 21.0 6.9 6.7 9.8 2.6 1 1 0 2 2 2 0 Prefoldin subunit DUF641 PF04859.12 KFP04531.1 - 8.8 6.7 23.4 11 6.3 5.3 3.3 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) CENP-H PF05837.12 KFP04531.1 - 9.6 6.7 21.6 8.1 6.9 6.9 2.8 1 1 0 2 2 2 0 Centromere protein H (CENP-H) Spc7 PF08317.11 KFP04531.1 - 9.9 4.9 27.8 8.4 5.2 6.7 2.9 1 1 0 2 2 2 0 Spc7 kinetochore protein Tweety PF04906.13 KFP04532.1 - 7.6e-171 568.3 11.6 9.1e-171 568.0 11.6 1.0 1 0 0 1 1 1 1 Tweety DUF2721 PF11026.8 KFP04532.1 - 0.0016 18.3 0.4 0.0016 18.3 0.4 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2721) DUF4131 PF13567.6 KFP04532.1 - 0.011 15.4 0.6 0.011 15.4 0.6 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Pex24p PF06398.11 KFP04532.1 - 0.11 11.4 0.0 0.59 9.1 0.0 2.1 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin Prominin PF05478.11 KFP04532.1 - 3.1 5.6 13.6 0.096 10.6 2.7 2.6 2 1 0 3 3 3 0 Prominin MgtE PF01769.16 KFP04532.1 - 3.7 7.9 8.5 2.8 8.3 0.7 2.8 3 0 0 3 3 3 0 Divalent cation transporter DUF3413 PF11893.8 KFP04532.1 - 6.6 5.8 8.9 0.28 10.3 2.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) Fringe PF02434.16 KFP04533.1 - 5.8e-107 356.8 0.0 6.5e-107 356.7 0.0 1.0 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 KFP04533.1 - 0.00071 19.4 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Gal-bind_lectin PF00337.22 KFP04534.1 - 4.6e-35 120.1 0.1 5.1e-35 119.9 0.1 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin 7tm_1 PF00001.21 KFP04535.1 - 1.8e-43 148.8 16.2 2e-43 148.6 16.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP04535.1 - 2e-07 30.9 14.2 7.6e-07 29.0 9.8 2.0 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP04535.1 - 0.0001 22.1 3.7 0.0001 22.1 3.7 1.6 1 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srv PF10323.9 KFP04535.1 - 0.0061 15.9 8.4 0.013 14.8 8.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Serpentine_r_xa PF03383.15 KFP04535.1 - 0.012 15.6 2.8 0.012 15.6 2.8 2.3 1 1 1 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa DUF2434 PF10361.9 KFP04535.1 - 0.21 10.6 9.5 0.65 8.9 1.5 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2434) Sulfotransfer_2 PF03567.14 KFP04536.1 - 4.1e-64 216.9 2.3 6.1e-64 216.4 2.3 1.3 1 0 0 1 1 1 1 Sulfotransferase family eIF2A PF08662.11 KFP04537.1 - 4.2e-72 242.1 6.7 2e-66 223.6 2.1 4.1 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KFP04537.1 - 6.2e-07 29.1 0.1 1.4e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC4_WD40 PF12894.7 KFP04537.1 - 9.9e-06 25.8 2.2 0.98 9.8 0.0 6.1 4 2 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Methyltr_RsmF_N PF17125.5 KFP04537.1 - 0.042 14.4 0.2 2.3 8.8 0.0 3.5 2 1 1 3 3 3 0 N-terminal domain of 16S rRNA methyltransferase RsmF Nup35_RRM PF05172.13 KFP04537.1 - 0.061 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PD40 PF07676.12 KFP04537.1 - 0.21 11.6 4.6 66 3.6 0.1 4.9 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 KFP04537.1 - 0.32 11.9 5.2 2.1e+02 3.0 0.1 6.1 6 1 0 6 6 6 0 WD domain, G-beta repeat PX PF00787.24 KFP04538.1 - 1.7e-21 76.3 2.0 1.7e-21 76.3 2.0 2.0 2 1 0 2 2 2 1 PX domain Perilipin PF03036.16 KFP04538.1 - 0.0013 17.8 2.8 0.0085 15.2 2.6 2.0 2 0 0 2 2 2 1 Perilipin family EPSP_synthase PF00275.20 KFP04538.1 - 0.093 11.4 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) NUDIX PF00293.28 KFP04539.1 - 5.1e-15 55.7 0.1 6.5e-15 55.3 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain FtsJ PF01728.19 KFP04540.1 - 2.3e-53 180.9 0.0 2.9e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 KFP04540.1 - 0.014 15.2 0.1 4.8 7.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain TPIP1 PF15338.6 KFP04540.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 p53-regulated apoptosis-inducing protein 1 MAD PF05557.13 KFP04541.1 - 2.5e-236 786.2 101.8 2.8e-236 786.0 101.8 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein TSC22 PF01166.18 KFP04541.1 - 1e-05 25.7 5.1 1e-05 25.7 5.1 10.4 8 2 2 10 10 10 3 TSC-22/dip/bun family DUF4200 PF13863.6 KFP04541.1 - 0.0017 18.8 9.0 0.0017 18.8 9.0 8.2 4 3 2 6 6 6 1 Domain of unknown function (DUF4200) LRR_8 PF13855.6 KFP04542.1 - 8.3e-24 83.1 11.5 7.3e-13 48.1 0.3 3.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFP04542.1 - 4.9e-10 39.5 11.2 0.00034 21.0 0.4 3.7 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP04542.1 - 1.2e-08 35.0 0.4 2.6e-08 33.9 0.4 1.6 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP04542.1 - 0.00076 19.0 3.3 0.017 14.6 0.3 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFP04542.1 - 0.00097 19.4 5.8 25 5.9 0.0 5.3 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.6 KFP04542.1 - 0.071 13.2 7.9 5.7 7.3 0.1 4.6 4 0 0 4 4 4 0 Leucine Rich repeat PAC3 PF10178.9 KFP04543.1 - 8.6e-29 99.5 0.0 1.3e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 Solute_trans_a PF03619.16 KFP04544.1 - 6.1e-94 314.4 23.0 7.8e-94 314.1 23.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha bZIP_Maf PF03131.17 KFP04545.1 - 1.6e-34 118.3 12.5 1.9e-34 118.0 12.5 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor DivIC PF04977.15 KFP04545.1 - 0.00011 21.9 5.0 0.00011 21.9 5.0 2.1 1 1 1 2 2 2 1 Septum formation initiator bZIP_1 PF00170.21 KFP04545.1 - 0.0002 21.4 16.6 0.0046 17.0 16.6 2.4 1 1 0 1 1 1 1 bZIP transcription factor Cnn_1N PF07989.11 KFP04545.1 - 0.003 17.7 7.8 0.0074 16.4 7.7 1.8 1 1 0 1 1 1 1 Centrosomin N-terminal motif 1 DUF1192 PF06698.11 KFP04545.1 - 0.0054 16.8 6.2 0.043 13.9 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) Prominin PF05478.11 KFP04545.1 - 0.013 13.5 1.2 0.016 13.2 1.2 1.0 1 0 0 1 1 1 0 Prominin Spc24 PF08286.11 KFP04545.1 - 0.033 14.4 1.4 0.06 13.6 0.2 1.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 bZIP_2 PF07716.15 KFP04545.1 - 0.035 14.2 11.5 0.035 14.2 11.5 2.5 1 1 2 3 3 3 0 Basic region leucine zipper FapA PF03961.13 KFP04545.1 - 0.087 11.4 2.5 0.092 11.3 2.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DASH_Spc19 PF08287.11 KFP04545.1 - 0.25 11.2 10.1 0.35 10.7 10.1 1.2 1 0 0 1 1 1 0 Spc19 DUF4164 PF13747.6 KFP04545.1 - 0.28 11.5 8.3 0.66 10.3 8.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) GIT_CC PF16559.5 KFP04545.1 - 0.3 11.0 4.6 0.16 11.8 1.7 2.1 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Mst1_SARAH PF11629.8 KFP04545.1 - 0.34 11.0 6.3 7.6 6.7 2.0 2.6 2 1 0 2 2 2 0 C terminal SARAH domain of Mst1 YabA PF06156.13 KFP04545.1 - 0.36 11.5 6.9 0.16 12.7 2.5 2.0 1 1 1 2 2 2 0 Initiation control protein YabA Nup54 PF13874.6 KFP04545.1 - 1.1 9.3 8.6 1.9 8.6 8.6 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Spc7 PF08317.11 KFP04545.1 - 1.4 7.7 9.5 2.3 7.0 9.5 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein ZapB PF06005.12 KFP04545.1 - 2.2 8.8 13.5 4.2 7.9 7.8 2.4 1 1 1 2 2 2 0 Cell division protein ZapB DUF2205 PF10224.9 KFP04545.1 - 2.8 8.0 8.2 0.83 9.7 3.1 2.2 1 1 1 2 2 2 0 Short coiled-coil protein XkdW PF09636.10 KFP04545.1 - 8.5 6.5 6.4 6.2 7.0 2.4 2.1 1 1 1 2 2 2 0 XkdW protein APG6_N PF17675.1 KFP04545.1 - 8.9 6.8 12.9 27 5.3 12.9 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region Glyco_hydro_31 PF01055.26 KFP04546.1 - 1.2e-160 535.6 0.1 1.4e-160 535.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KFP04546.1 - 1.8e-13 50.7 0.1 2.9e-13 50.0 0.1 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KFP04546.1 - 1.1e-10 41.6 0.3 1.2e-09 38.3 0.1 2.8 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KFP04546.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) DUF3677 PF12432.8 KFP04547.1 - 5.7e-32 109.9 9.8 7.5e-32 109.5 3.9 3.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3677) UNC45-central PF11701.8 KFP04547.1 - 0.0059 16.6 4.0 0.25 11.3 0.1 5.1 4 1 1 5 5 5 1 Myosin-binding striated muscle assembly central DUF3585 PF12130.8 KFP04548.1 - 1.9e-39 134.9 26.0 3.2e-39 134.2 26.0 1.4 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain CH PF00307.31 KFP04548.1 - 7e-24 84.1 0.0 1.6e-23 83.0 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFP04548.1 - 4.1e-09 36.2 0.0 8.8e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain LIM PF00412.22 KFP04548.1 - 1.5e-05 25.1 3.7 4.7e-05 23.5 3.7 1.9 1 0 0 1 1 1 1 LIM domain zf-AN1 PF01428.16 KFP04549.1 - 7.7e-20 70.8 25.3 6.5e-12 45.4 10.5 2.8 3 0 0 3 3 3 2 AN1-like Zinc finger IBR PF01485.21 KFP04549.1 - 0.15 12.3 25.2 4.3 7.6 17.3 3.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Tropomodulin PF03250.14 KFP04549.1 - 0.16 12.0 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Tropomodulin Transp_Tc5_C PF04236.15 KFP04549.1 - 0.17 12.2 17.5 0.86 10.0 6.4 2.7 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain zf-C3HC PF07967.13 KFP04549.1 - 0.29 11.2 7.3 0.17 12.0 1.1 2.2 2 0 0 2 2 2 0 C3HC zinc finger-like zinc_ribbon_4 PF13717.6 KFP04549.1 - 1 9.3 12.0 1.5 8.8 0.7 3.8 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2H2_4 PF13894.6 KFP04549.1 - 1.9 9.5 9.8 19 6.4 0.7 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-RRN7 PF11781.8 KFP04549.1 - 7.3 6.4 10.1 7.7 6.3 0.3 3.3 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 7tm_1 PF00001.21 KFP04550.1 - 1.3e-41 142.7 17.1 1.9e-41 142.2 17.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP04550.1 - 8.6e-05 22.0 16.1 0.00012 21.6 16.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Abhydrolase_9_N PF15420.6 KFP04550.1 - 0.87 9.6 3.4 1.4 8.9 3.4 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus PHO4 PF01384.20 KFP04550.1 - 2.6 7.0 6.6 0.94 8.5 4.2 1.5 1 1 1 2 2 2 0 Phosphate transporter family 7tm_1 PF00001.21 KFP04552.1 - 1.4e-13 50.8 16.6 2.1e-13 50.2 16.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Col_cuticle_N PF01484.17 KFP04552.1 - 1.1 9.4 0.1 1.1 9.4 0.1 3.1 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain DUF2373 PF10180.9 KFP04553.1 - 2.7e-23 81.6 0.3 4.2e-23 81.0 0.3 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) p450 PF00067.22 KFP04554.1 - 1.4e-124 416.4 0.7 1.5e-124 416.3 0.7 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFP04555.1 - 1.1e-118 397.0 0.6 1.2e-118 396.8 0.6 1.0 1 0 0 1 1 1 1 Cytochrome P450 ArfGap PF01412.18 KFP04556.1 - 3e-28 98.2 0.1 5.1e-28 97.5 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 KFP04556.1 - 1.1e-22 80.5 0.3 6.6e-13 49.1 0.1 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KFP04556.1 - 1.3e-08 35.2 2.0 2.8e-05 24.5 0.4 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 KFP04556.1 - 0.0001 22.5 4.1 0.08 13.2 0.1 2.9 3 1 0 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.6 KFP04556.1 - 0.0011 19.0 0.2 0.19 11.8 0.0 2.8 3 0 0 3 3 3 1 PH domain DUF410 PF04190.13 KFP04557.1 - 4.9e-66 223.1 0.1 2.9e-64 217.3 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF410) SDH_C PF18317.1 KFP04557.1 - 0.27 11.0 1.0 1.3 8.9 0.9 2.2 2 0 0 2 2 2 0 Shikimate 5'-dehydrogenase C-terminal domain Sad1_UNC PF07738.13 KFP04558.1 - 1.8e-45 154.2 0.0 7.6e-45 152.2 0.0 2.0 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal MRP PF09387.10 KFP04558.1 - 2.1e-38 132.3 0.7 3.6e-38 131.5 0.7 1.3 1 0 0 1 1 1 1 Mitochondrial RNA binding protein MRP Sun2_CC2 PF18580.1 KFP04558.1 - 4.7e-11 42.7 2.6 2.7e-10 40.3 2.8 2.3 2 0 0 2 2 2 1 SUN2 coiled coil domain 2 HEAT_2 PF13646.6 KFP04559.1 - 9.3e-13 48.4 0.5 6.7e-05 23.2 0.0 6.0 3 2 1 5 5 5 3 HEAT repeats Vac14_Fab1_bd PF12755.7 KFP04559.1 - 2e-09 37.9 0.5 0.062 13.9 0.0 5.1 3 2 2 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KFP04559.1 - 1.3e-06 28.1 24.5 0.13 12.6 0.3 9.2 10 0 0 10 10 9 2 HEAT repeat CLASP_N PF12348.8 KFP04559.1 - 1e-05 25.2 8.6 0.24 10.9 0.0 4.9 4 2 1 5 5 5 2 CLASP N terminal HEAT_EZ PF13513.6 KFP04559.1 - 2.4e-05 24.7 12.0 0.59 10.7 0.2 7.6 8 0 0 8 8 8 1 HEAT-like repeat MMS19_N PF14500.6 KFP04559.1 - 0.0055 16.3 4.9 8.7 5.8 0.1 4.7 4 1 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II Tti2 PF10521.9 KFP04559.1 - 0.0072 15.9 3.1 3.7 7.0 0.4 4.7 3 1 0 3 3 3 1 Tti2 family IFRD PF05004.13 KFP04559.1 - 0.012 14.7 0.1 0.012 14.7 0.1 3.8 3 2 2 5 5 5 0 Interferon-related developmental regulator (IFRD) NUC173 PF08161.12 KFP04559.1 - 0.03 14.0 5.3 11 5.6 0.2 4.4 5 1 0 5 5 5 0 NUC173 domain UME PF08064.13 KFP04559.1 - 0.03 14.2 7.3 11 6.0 0.0 4.1 4 1 0 4 4 4 0 UME (NUC010) domain Telomere_reg-2 PF10193.9 KFP04559.1 - 0.052 14.0 5.6 0.13 12.7 1.5 3.5 3 0 0 3 3 3 0 Telomere length regulation protein RTP1_C1 PF10363.9 KFP04559.1 - 0.055 13.7 1.1 38 4.5 0.1 4.1 2 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF2201_N PF13203.6 KFP04559.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain cNMP_binding PF00027.29 KFP04560.1 - 1.6e-42 143.5 0.1 1.8e-20 72.8 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 KFP04560.1 - 7.5e-14 51.1 0.1 1.5e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DUF5582 PF17819.1 KFP04560.1 - 0.017 15.6 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5582) DUF5586 PF17824.1 KFP04560.1 - 0.1 11.7 0.3 0.18 10.8 0.1 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5586) PDGF PF00341.17 KFP04561.1 - 1.1e-21 76.9 10.1 1.7e-21 76.3 10.1 1.3 1 0 0 1 1 1 1 PDGF/VEGF domain PDGF_N PF04692.13 KFP04561.1 - 7.3e-06 26.7 1.7 1e-05 26.2 0.1 1.9 2 0 0 2 2 2 1 Platelet-derived growth factor, N terminal region Forkhead PF00250.18 KFP04562.1 - 2.3e-37 127.1 0.2 2.8e-37 126.8 0.2 1.1 1 0 0 1 1 1 1 Forkhead domain DUF3277 PF11681.8 KFP04562.1 - 0.057 13.3 0.0 0.071 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) Fam20C PF06702.12 KFP04563.1 - 2.5e-106 354.4 0.2 3.4e-106 354.0 0.2 1.2 1 0 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 FAT PF02259.23 KFP04565.1 - 5.2e-66 223.2 9.9 1.4e-65 221.8 9.9 1.8 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 KFP04565.1 - 9.7e-16 58.3 0.0 2.6e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KFP04565.1 - 1.7e-05 24.5 0.3 8.7e-05 22.3 0.1 2.5 2 0 0 2 2 2 1 FATC domain HEAT_EZ PF13513.6 KFP04565.1 - 0.048 14.2 1.9 2.9 8.5 0.2 4.8 5 0 0 5 5 5 0 HEAT-like repeat ACDC PF14733.6 KFP04565.1 - 0.2 12.0 2.0 1.1 9.6 0.3 3.3 2 0 0 2 2 2 0 AP2-coincident C-terminal DUF3361 PF11841.8 KFP04565.1 - 0.22 11.4 3.2 0.68 9.9 0.3 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) Sec7_N PF12783.7 KFP04565.1 - 0.94 9.4 16.1 0.53 10.2 3.4 5.8 4 2 2 6 6 6 0 Guanine nucleotide exchange factor in Golgi transport N-terminal TPR_2 PF07719.17 KFP04565.1 - 1 9.6 5.5 5.5 7.4 0.9 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3385 PF11865.8 KFP04565.1 - 6.2 6.7 8.1 2.5 8.0 0.2 4.7 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) PKD PF00801.20 KFP04566.1 - 7.7e-05 22.5 0.1 0.21 11.5 0.1 2.7 2 0 0 2 2 2 2 PKD domain PalH PF08733.10 KFP04566.1 - 0.016 14.2 0.2 0.029 13.4 0.2 1.3 1 0 0 1 1 1 0 PalH/RIM21 Pentaxin PF00354.17 KFP04567.1 - 3.8e-34 118.1 0.0 5.6e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.6 KFP04567.1 - 3e-14 53.4 0.0 4.7e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily SlyX PF04102.12 KFP04567.1 - 0.00029 21.4 7.0 0.28 11.8 0.2 3.1 3 0 0 3 3 3 2 SlyX T3SS_basalb_I PF17001.5 KFP04567.1 - 0.031 14.9 0.1 0.077 13.6 0.1 1.6 1 0 0 1 1 1 0 Type III secretion basal body protein I, YscI, HrpB, PscI GOLGA2L5 PF15070.6 KFP04567.1 - 0.048 12.3 4.8 0.067 11.8 4.8 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Sun2_CC2 PF18580.1 KFP04567.1 - 0.049 13.9 3.8 0.21 11.8 1.2 2.5 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 LIAS_N PF16881.5 KFP04567.1 - 0.1 13.0 0.1 0.32 11.4 0.1 1.9 1 1 0 1 1 1 0 N-terminal domain of lipoyl synthase of Radical_SAM family Laminin_G_2 PF02210.24 KFP04567.1 - 0.12 13.0 0.0 0.23 12.1 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain DUF1664 PF07889.12 KFP04567.1 - 0.16 12.0 0.4 25 4.9 0.0 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) NBP1 PF08537.10 KFP04567.1 - 0.25 10.7 1.4 0.39 10.1 1.4 1.2 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 CCDC-167 PF15188.6 KFP04567.1 - 0.26 11.7 1.7 0.66 10.4 1.7 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 CdvA PF18822.1 KFP04567.1 - 0.83 9.5 3.8 12 5.8 1.7 2.8 1 1 2 3 3 3 0 CdvA-like coiled-coil domain Apolipoprotein PF01442.18 KFP04567.1 - 3.9 7.3 10.4 0.19 11.6 3.7 2.0 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain PRKG1_interact PF15898.5 KFP04567.1 - 4.8 8.1 7.6 1 10.3 3.6 1.8 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Actin PF00022.19 KFP04568.1 - 6.1e-151 502.6 0.0 2e-150 501.0 0.0 1.6 1 1 0 1 1 1 1 Actin ubiquitin PF00240.23 KFP04570.1 - 1.5e-08 34.2 0.0 3.5e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KFP04570.1 - 1.8e-05 24.5 0.0 4.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 KFP04570.1 - 0.0084 15.9 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Rad60-SLD PF11976.8 KFP04570.1 - 0.012 15.4 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KFP04570.1 - 0.078 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Sema PF01403.19 KFP04571.1 - 6.3e-24 84.6 0.0 6.9e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 Sema domain p450 PF00067.22 KFP04572.1 - 4.2e-23 81.8 0.2 4.5e-23 81.7 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 PKD PF00801.20 KFP04573.1 - 0.12 12.3 0.5 0.44 10.4 0.0 2.1 3 0 0 3 3 3 0 PKD domain RBP_receptor PF14752.6 KFP04574.1 - 5.2e-251 834.5 22.4 5.8e-251 834.4 22.4 1.0 1 0 0 1 1 1 1 Retinol binding protein receptor LRR_8 PF13855.6 KFP04575.1 - 1.4e-25 88.8 12.4 3.9e-14 52.1 4.6 2.1 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFP04575.1 - 2.1e-14 53.4 9.5 3.9e-07 30.3 2.1 3.3 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP04575.1 - 3.6e-07 29.8 0.1 4.5e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 KFP04575.1 - 3.8e-06 26.7 7.7 0.84 10.4 0.3 4.7 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_5 PF13306.6 KFP04575.1 - 6.3e-05 22.9 0.0 8.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) TPKR_C2 PF16920.5 KFP04575.1 - 0.0086 16.2 0.8 0.021 14.9 0.3 2.0 2 0 0 2 2 2 1 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_6 PF13516.6 KFP04575.1 - 0.026 14.5 0.5 0.026 14.5 0.5 4.1 5 0 0 5 5 5 0 Leucine Rich repeat LRR_8 PF13855.6 KFP04576.1 - 3.8e-20 71.4 8.7 2.4e-11 43.2 1.1 2.2 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFP04576.1 - 8.5e-12 45.1 11.5 0.00013 22.2 2.8 3.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP04576.1 - 1.9e-06 27.5 1.1 0.0028 17.2 0.1 1.9 1 1 0 1 1 1 1 Leucine-rich repeat LRR_5 PF13306.6 KFP04576.1 - 5.3e-06 26.4 0.1 9.4e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFP04576.1 - 0.00083 19.6 8.3 1.5 9.7 0.1 4.8 4 1 0 4 4 4 1 Leucine Rich Repeat TPKR_C2 PF16920.5 KFP04576.1 - 0.0014 18.7 1.5 0.0014 18.7 1.5 2.1 2 0 0 2 2 2 1 Tyrosine-protein kinase receptor C2 Ig-like domain Beta_helix PF13229.6 KFP04576.1 - 0.14 12.0 0.0 0.27 11.0 0.0 1.4 1 1 0 1 1 1 0 Right handed beta helix region LRR_6 PF13516.6 KFP04576.1 - 0.42 10.8 6.1 1.2 9.3 0.1 3.5 4 0 0 4 4 4 0 Leucine Rich repeat Zona_pellucida PF00100.23 KFP04577.1 - 3.2e-43 148.4 0.0 3.7e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.23 KFP04578.1 - 4e-45 154.6 0.0 4.6e-45 154.4 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Dymeclin PF09742.9 KFP04579.1 - 2.6e-10 39.4 0.5 2.7e-10 39.3 0.5 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein RVT_1 PF00078.27 KFP04580.1 - 0.0051 16.4 0.0 0.0082 15.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ig_3 PF13927.6 KFP04581.1 - 3.1e-21 75.8 1.6 2.6e-11 43.9 0.1 3.4 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 KFP04581.1 - 6.7e-19 68.1 2.2 1.7e-15 57.1 0.0 3.8 3 1 1 4 4 4 2 Immunoglobulin V-set domain ig PF00047.25 KFP04581.1 - 4.7e-17 61.9 2.8 2.4e-08 34.0 0.2 3.5 3 1 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KFP04581.1 - 2.2e-15 56.8 0.5 3.8e-08 33.6 0.2 3.5 3 1 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFP04581.1 - 1.9e-12 47.1 0.1 7.7e-06 25.9 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_5 PF16681.5 KFP04581.1 - 0.013 15.9 0.0 0.51 10.8 0.0 2.9 3 0 0 3 3 3 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFP04581.1 - 0.013 15.0 0.1 6.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain DUF3619 PF12279.8 KFP04581.1 - 0.032 14.6 0.0 0.06 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) EphA2_TM PF14575.6 KFP04581.1 - 0.037 14.9 0.0 0.064 14.1 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FAM163 PF15069.6 KFP04581.1 - 0.082 13.3 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 FAM163 family Shisa PF13908.6 KFP04581.1 - 0.11 12.7 0.1 0.28 11.4 0.0 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF5582 PF17819.1 KFP04582.1 - 2.7e-25 89.5 1.7 4.2e-25 88.9 1.7 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5582) DUF5586 PF17824.1 KFP04582.1 - 0.00016 20.9 0.2 0.00029 20.1 0.2 1.4 2 0 0 2 2 2 1 Family of unknown function (DUF5586) RIIa PF02197.17 KFP04582.1 - 0.027 14.1 0.1 0.044 13.5 0.1 1.3 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Tetraspanin PF00335.20 KFP04583.1 - 1.4e-28 100.2 5.3 1.7e-28 99.9 5.3 1.0 1 0 0 1 1 1 1 Tetraspanin family UPF0220 PF05255.11 KFP04583.1 - 3 7.4 8.9 9.3 5.8 0.4 2.5 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0220) RhoGAP PF00620.27 KFP04584.1 - 6.8e-32 110.4 0.4 1.6e-31 109.2 0.4 1.6 1 0 0 1 1 1 1 RhoGAP domain Glyco_transf_43 PF03360.16 KFP04585.1 - 3.3e-72 242.6 0.0 3.8e-72 242.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 Glyco_transf_7N PF13733.6 KFP04586.1 - 6.9e-59 197.3 0.1 1e-58 196.8 0.1 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 KFP04586.1 - 7.4e-28 96.0 0.3 1.8e-27 94.8 0.3 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Phycoerythr_ab PF02972.14 KFP04586.1 - 0.032 14.0 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 Phycoerythrin, alpha/beta chain Glyco_tranf_2_2 PF10111.9 KFP04586.1 - 0.11 11.9 0.0 0.36 10.3 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Tmp39 PF10271.9 KFP04587.1 - 8e-178 591.9 18.1 9.2e-178 591.7 18.1 1.0 1 0 0 1 1 1 1 Putative transmembrane protein Amidase PF01425.21 KFP04588.1 - 6.3e-89 299.0 0.0 4.3e-88 296.3 0.0 1.8 1 1 0 1 1 1 1 Amidase SNF2_N PF00176.23 KFP04589.1 - 8.8e-56 189.1 0.4 2.4e-55 187.7 0.4 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KFP04589.1 - 1.2e-12 48.2 0.0 3.1e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFP04589.1 - 3.2e-11 43.6 0.0 1.5e-09 38.2 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFP04589.1 - 1.1e-07 31.7 0.0 2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KFP04589.1 - 0.0011 18.2 0.0 0.0046 16.2 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.6 KFP04589.1 - 0.021 15.1 0.0 0.1 12.9 0.0 2.2 1 1 0 1 1 1 0 AAA domain TT_ORF2 PF02957.15 KFP04589.1 - 0.083 13.8 0.7 0.22 12.4 0.7 1.7 1 0 0 1 1 1 0 TT viral ORF2 MCU PF04678.13 KFP04589.1 - 1.3 9.1 4.6 3.2 7.8 2.4 2.3 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Strabismus PF06638.11 KFP04590.1 - 3.9e-256 850.5 0.1 4.7e-256 850.2 0.1 1.0 1 0 0 1 1 1 1 Strabismus protein CDT1_C PF16679.5 KFP04590.1 - 0.03 14.8 2.7 0.059 13.8 2.4 1.6 1 1 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain Calsequestrin PF01216.17 KFP04591.1 - 2.4e-212 704.9 43.3 1.1e-211 702.8 43.3 1.8 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_6 PF13848.6 KFP04591.1 - 2.4e-21 76.5 4.5 2e-19 70.2 2.3 2.3 2 1 0 2 2 2 2 Thioredoxin-like domain SDA1 PF05285.12 KFP04591.1 - 0.14 11.6 17.8 0.2 11.1 17.8 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 KFP04591.1 - 3 6.0 20.5 4.4 5.5 20.5 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 KFP04591.1 - 6.4 6.0 12.1 8.8 5.5 12.1 1.3 1 0 0 1 1 1 0 BUD22 Sugar_tr PF00083.24 KFP04592.1 - 6.7e-30 104.3 14.7 9.3e-30 103.9 14.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP04592.1 - 2.9e-27 95.5 43.5 9.3e-25 87.3 30.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Mab-21 PF03281.14 KFP04593.1 - 4.6e-83 278.9 5.3 6.1e-83 278.5 5.3 1.2 1 0 0 1 1 1 1 Mab-21 protein Yae1_N PF09811.9 KFP04594.1 - 1.1e-12 47.4 58.0 0.0078 15.9 9.7 5.9 3 2 0 3 3 3 3 Essential protein Yae1, N terminal Cation_ATPase_C PF00689.21 KFP04595.1 - 4.7e-44 150.3 0.3 4.7e-44 150.3 0.3 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KFP04595.1 - 1.6e-43 148.3 0.5 1.6e-43 148.3 0.5 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KFP04595.1 - 8.5e-24 83.5 0.0 2e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFP04595.1 - 8.3e-19 68.7 0.2 3.7e-15 56.8 0.2 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFP04595.1 - 4.3e-18 64.7 0.0 8.2e-18 63.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFP04595.1 - 7.4e-06 25.9 1.1 0.00084 19.2 0.5 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF742 PF05331.11 KFP04595.1 - 0.11 12.3 0.0 15 5.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF742) Ig_3 PF13927.6 KFP04596.1 - 1.5e-11 44.7 0.0 5.1e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP04596.1 - 1.2e-07 31.8 0.0 8.2e-06 25.9 0.0 2.3 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFP04596.1 - 2.2e-06 27.6 0.2 7.8e-05 22.7 0.0 2.4 2 1 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP04596.1 - 0.00015 22.1 0.6 0.018 15.4 0.0 2.4 2 1 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFP04596.1 - 0.00024 21.2 0.2 0.011 15.9 0.1 2.6 2 1 0 2 2 2 1 Immunoglobulin V-set domain Receptor_2B4 PF11465.8 KFP04596.1 - 0.0037 17.5 0.1 0.0088 16.2 0.0 1.6 2 0 0 2 2 2 1 Natural killer cell receptor 2B4 DUF2139 PF09910.9 KFP04596.1 - 0.069 12.3 0.1 0.09 11.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2139) Lipase PF00151.19 KFP04597.1 - 5.2e-100 335.0 0.0 7e-100 334.6 0.0 1.2 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 KFP04597.1 - 0.0012 19.5 2.4 0.0017 19.0 2.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Popeye PF04831.13 KFP04598.1 - 9.3e-50 168.4 0.3 1.1e-49 168.2 0.3 1.1 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.29 KFP04598.1 - 0.0017 18.4 0.0 0.0037 17.3 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain CAP_N PF01213.19 KFP04598.1 - 0.27 10.7 7.7 0.37 10.2 7.7 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TMEM208_SND2 PF05620.11 KFP04598.1 - 0.74 9.6 4.1 0.85 9.4 3.3 1.5 1 1 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 CFAP91 PF14738.6 KFP04599.1 - 1.2e-61 207.3 8.8 1.9e-61 206.6 8.4 1.6 2 0 0 2 2 2 1 Cilia- and flagella-associated protein 91 eIF-4B PF06273.11 KFP04599.1 - 0.47 9.4 5.3 0.64 9.0 5.3 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Pkinase PF00069.25 KFP04600.1 - 7.7e-69 232.0 0.0 9e-69 231.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP04600.1 - 2e-24 86.3 0.0 2.4e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP04600.1 - 3.7e-05 23.2 0.0 0.00032 20.1 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KFP04600.1 - 0.0042 17.0 0.1 0.014 15.4 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFP04600.1 - 0.02 14.3 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 KFP04600.1 - 0.065 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Choline_kinase PF01633.20 KFP04600.1 - 0.18 11.4 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase 7tm_3 PF00003.22 KFP04601.1 - 2.2e-39 135.6 18.8 3e-39 135.2 18.8 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NYD-SP28 PF14772.6 KFP04601.1 - 0.2 11.7 0.3 0.33 11.0 0.3 1.3 1 0 0 1 1 1 0 Sperm tail LRR_4 PF12799.7 KFP04602.1 - 3.8e-15 55.7 21.3 1.3e-07 31.8 0.1 3.6 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP04602.1 - 2.7e-13 49.5 12.3 1.6e-11 43.8 6.0 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 KFP04602.1 - 6.7e-05 22.5 0.5 0.00014 21.4 0.5 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 KFP04602.1 - 0.00019 21.5 13.6 1.4 9.7 0.0 6.0 5 1 0 5 5 5 2 Leucine Rich Repeat NDUF_B4 PF07225.12 KFP04603.1 - 1.4e-53 180.1 0.1 1.5e-53 179.9 0.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Pho86 PF11124.8 KFP04603.1 - 0.21 11.0 0.0 0.3 10.5 0.0 1.1 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 HgmA PF04209.13 KFP04604.1 - 7.3e-222 736.6 0.1 8.2e-222 736.4 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Roc PF08477.13 KFP04605.1 - 1.2e-15 57.8 0.0 5.8e-15 55.6 0.0 1.9 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP04605.1 - 2.4e-13 50.0 0.0 8.4e-13 48.2 0.0 1.8 1 1 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KFP04605.1 - 1.1e-05 25.5 0.0 1.5e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFP04605.1 - 4.6e-05 22.9 0.0 0.0001 21.7 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KFP04605.1 - 0.00019 20.9 0.2 0.00063 19.3 0.2 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFP04605.1 - 0.00049 20.1 0.1 0.0029 17.5 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KFP04605.1 - 0.0021 18.5 0.0 0.008 16.6 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain IIGP PF05049.13 KFP04605.1 - 0.0091 15.1 0.0 0.018 14.1 0.0 1.6 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 KFP04605.1 - 0.028 14.9 0.0 0.059 13.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KFP04605.1 - 0.038 13.7 0.0 0.094 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 KFP04605.1 - 0.039 13.2 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_5 PF07728.14 KFP04605.1 - 0.048 13.7 0.0 0.087 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 KFP04605.1 - 0.048 13.7 0.0 0.099 12.7 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain DUF815 PF05673.13 KFP04605.1 - 0.065 12.4 0.1 0.11 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KFP04605.1 - 0.082 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KFP04605.1 - 0.11 12.9 0.0 0.31 11.4 0.0 1.7 2 0 0 2 2 2 0 RNA helicase TFIIE_alpha PF02002.17 KFP04606.1 - 8.5e-36 122.0 0.6 1.5e-35 121.2 0.6 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 KFP04606.1 - 4.8e-30 103.7 5.3 1.5e-29 102.1 5.3 1.9 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.12 KFP04606.1 - 9.4e-12 44.2 1.0 1.8e-11 43.3 1.0 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 KFP04606.1 - 0.052 13.5 0.1 0.093 12.7 0.1 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-Sec23_Sec24 PF04810.15 KFP04606.1 - 0.13 12.3 0.4 11 6.2 0.1 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger PyrI_C PF02748.15 KFP04606.1 - 0.37 10.7 1.6 1.3 9.0 1.8 1.9 1 1 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_4 PF13894.6 KFP04606.1 - 0.98 10.4 3.0 5.9 8.0 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger LLGL PF08366.13 KFP04607.1 - 1.6e-34 118.3 0.2 2.5e-33 114.5 0.0 2.5 2 0 0 2 2 2 1 LLGL2 WD40 PF00400.32 KFP04607.1 - 1.7e-10 41.3 1.9 0.14 13.1 0.1 6.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP04607.1 - 2.8e-09 37.1 0.1 1.1 9.6 0.0 6.6 3 2 5 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Lgl_C PF08596.10 KFP04607.1 - 6.3e-06 25.1 0.0 0.00012 20.9 0.0 3.0 3 1 0 3 3 3 1 Lethal giant larvae(Lgl) like, C-terminal Synaptobrevin PF00957.21 KFP04607.1 - 0.0011 18.7 0.1 0.0025 17.6 0.1 1.5 1 0 0 1 1 1 1 Synaptobrevin ELYS-bb PF16687.5 KFP04607.1 - 0.026 13.2 0.0 1.8 7.1 0.0 2.5 2 1 0 2 2 2 0 beta-propeller of ELYS nucleoporin RAB3GAP2_N PF14655.6 KFP04607.1 - 0.03 13.6 0.0 2.9 7.0 0.0 2.9 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Frtz PF11768.8 KFP04607.1 - 0.074 11.3 0.0 0.2 9.9 0.0 1.6 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Death PF00531.22 KFP04608.1 - 1.1e-16 60.7 0.2 1.8e-16 60.1 0.2 1.3 1 0 0 1 1 1 1 Death domain TNFR_c6 PF00020.18 KFP04608.1 - 2.4e-15 56.6 58.7 6.1e-10 39.3 9.8 5.0 5 1 0 5 5 5 4 TNFR/NGFR cysteine-rich region NinF PF05810.12 KFP04608.1 - 0.034 14.0 1.0 0.034 14.0 1.0 2.7 3 0 0 3 3 3 0 NinF protein CTC1 PF15489.6 KFP04609.1 - 9.3e-50 169.2 0.3 1e-49 169.1 0.3 1.0 1 0 0 1 1 1 1 CST, telomere maintenance, complex subunit CTC1 Ig_3 PF13927.6 KFP04610.1 - 1e-10 42.0 0.7 4.4e-05 24.0 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFP04610.1 - 2.3e-10 40.6 0.2 4.2e-09 36.6 0.0 2.8 3 1 0 3 3 3 1 Immunoglobulin V-set domain I-set PF07679.16 KFP04610.1 - 3.5e-07 30.2 3.4 0.00073 19.6 0.0 3.8 2 2 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFP04610.1 - 1.2e-05 25.4 1.7 0.0004 20.5 0.0 3.3 1 1 1 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFP04610.1 - 3.2e-05 24.2 0.6 0.038 14.3 0.0 2.8 1 1 0 2 2 2 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFP04610.1 - 0.0045 17.0 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 Izumo-like Immunoglobulin domain C1-set PF07654.15 KFP04610.1 - 0.012 15.9 0.6 0.6 10.5 0.3 2.8 2 1 0 3 3 3 0 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFP04610.1 - 0.028 14.0 0.0 0.89 9.2 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain Receptor_2B4 PF11465.8 KFP04610.1 - 0.07 13.3 0.0 5.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 EpuA PF11772.8 KFP04610.1 - 0.091 12.5 3.0 0.17 11.6 3.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Filamin PF00630.19 KFP04611.1 - 6.4e-21 75.1 0.2 1.2e-20 74.3 0.2 1.4 1 0 0 1 1 1 1 Filamin/ABP280 repeat zf-B_box PF00643.24 KFP04611.1 - 6.7e-09 35.8 12.0 6.7e-09 35.8 12.0 3.4 3 0 0 3 3 3 1 B-box zinc finger Laminin_II PF06009.12 KFP04611.1 - 0.033 14.2 0.4 0.058 13.4 0.4 1.3 1 0 0 1 1 1 0 Laminin Domain II Wyosine_form PF08608.12 KFP04611.1 - 0.062 13.7 0.2 0.2 12.0 0.2 1.9 1 0 0 1 1 1 0 Wyosine base formation FEZ PF07763.13 KFP04611.1 - 0.099 12.4 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 FEZ-like protein Y_Y_Y PF07495.13 KFP04611.1 - 0.11 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Y_Y_Y domain Clusterin PF01093.17 KFP04611.1 - 5.4 5.9 8.8 1.2 8.2 0.7 2.1 2 0 0 2 2 2 0 Clusterin SPICE PF15678.5 KFP04612.1 - 1e-149 499.4 27.4 1e-149 499.4 27.4 2.6 2 1 1 3 3 3 1 Centriole duplication and mitotic chromosome congression SOGA PF11365.8 KFP04612.1 - 0.024 15.8 0.1 0.024 15.8 0.1 4.5 4 1 1 5 5 5 0 Protein SOGA DUF2461 PF09365.10 KFP04612.1 - 0.43 10.5 5.6 1.4 8.8 0.6 3.1 3 1 0 3 3 3 0 Conserved hypothetical protein (DUF2461) COE1_HLH PF16423.5 KFP04613.1 - 5.3e-37 125.3 3.0 3.7e-30 103.4 0.4 2.4 2 0 0 2 2 2 2 Transcription factor COE1 helix-loop-helix domain COE1_DBD PF16422.5 KFP04613.1 - 3.7e-33 114.9 2.7 5.1e-33 114.4 2.7 1.2 1 0 0 1 1 1 1 Transcription factor COE1 DNA-binding domain TIG PF01833.24 KFP04613.1 - 3.1e-12 46.4 0.3 3.1e-12 46.4 0.3 2.5 3 0 0 3 3 3 1 IPT/TIG domain HLH PF00010.26 KFP04613.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain TRC8_N PF13705.6 KFP04614.1 - 2.3e-135 452.4 40.2 2.8e-135 452.1 40.2 1.1 1 0 0 1 1 1 1 TRC8 N-terminal domain zf-RING_2 PF13639.6 KFP04614.1 - 5.4e-10 39.4 7.2 5.4e-10 39.4 7.2 2.0 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP04614.1 - 3.3e-09 36.4 7.2 9.6e-09 35.0 7.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFP04614.1 - 6.2e-08 32.8 6.9 1.7e-07 31.4 6.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFP04614.1 - 1.3e-06 28.3 1.2 1.3e-06 28.3 1.2 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFP04614.1 - 4.2e-06 26.5 6.5 4.2e-06 26.5 6.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP04614.1 - 7.8e-06 25.7 8.7 7.8e-06 25.7 8.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP04614.1 - 3.8e-05 23.5 8.7 3.8e-05 23.5 8.7 1.7 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KFP04614.1 - 0.00018 21.1 4.4 0.00018 21.1 4.4 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KFP04614.1 - 0.0025 17.7 10.4 0.0025 17.7 10.4 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KFP04614.1 - 0.015 15.3 7.0 0.038 14.0 7.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFP04614.1 - 0.5 10.0 15.0 0.11 12.2 8.4 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-P11 PF03854.14 KFP04614.1 - 0.71 9.6 7.7 3.3 7.4 7.7 2.2 1 0 0 1 1 1 0 P-11 zinc finger NIF PF03031.18 KFP04615.1 - 1.7e-30 105.8 0.2 2.6e-30 105.2 0.2 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 KFP04615.1 - 7e-08 32.1 0.1 1.6e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family DUF705 PF05152.12 KFP04615.1 - 0.0017 17.9 0.1 0.0028 17.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF705) Ubiquitin_2 PF14560.6 KFP04615.1 - 0.013 16.0 0.1 0.034 14.6 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain Kazal_1 PF00050.21 KFP04616.1 - 2.2e-18 66.0 4.6 2.5e-18 65.8 4.6 1.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KFP04616.1 - 5.6e-09 36.0 2.6 7.4e-09 35.6 2.6 1.2 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFP04617.1 - 1.9e-51 171.9 30.7 5.6e-18 64.7 5.5 3.1 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KFP04617.1 - 2.7e-27 94.6 27.9 1.4e-10 41.1 4.8 3.5 3 1 0 3 3 3 3 Kazal-type serine protease inhibitor domain zf-BED PF02892.15 KFP04617.1 - 0.76 9.9 9.4 1.8 8.7 0.6 3.8 3 1 1 4 4 4 0 BED zinc finger DUF393 PF04134.12 KFP04617.1 - 9 7.7 11.6 44 5.5 0.3 3.4 3 1 0 3 3 3 0 Protein of unknown function, DUF393 Kazal_1 PF00050.21 KFP04618.1 - 3.4e-113 369.6 64.8 1.9e-20 72.6 4.5 6.1 6 0 0 6 6 6 6 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KFP04618.1 - 1e-60 201.6 47.5 8.1e-11 41.9 2.6 6.3 6 0 0 6 6 6 6 Kazal-type serine protease inhibitor domain FmdE PF02663.14 KFP04618.1 - 0.068 13.2 6.8 0.56 10.3 0.2 3.6 3 0 0 3 3 3 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Kazal_1 PF00050.21 KFP04619.1 - 1.1e-11 44.5 2.6 1.1e-11 44.5 2.6 1.1 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KFP04619.1 - 3.9e-06 26.9 0.9 4.3e-06 26.7 0.9 1.1 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain 7tm_1 PF00001.21 KFP04620.1 - 1.9e-70 237.2 19.2 2.3e-70 236.9 19.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP04620.1 - 1.3e-12 47.7 15.7 1.7e-12 47.3 15.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP04620.1 - 1.5e-07 31.5 12.7 1e-06 28.7 13.7 1.9 2 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP04620.1 - 6.9e-05 22.6 15.7 6.9e-05 22.6 15.7 1.8 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx T_cell_tran_alt PF15128.6 KFP04620.1 - 0.067 13.0 1.2 1.2 9.0 0.2 2.4 2 0 0 2 2 2 0 T-cell leukemia translocation-altered CoxIIa PF08113.11 KFP04620.1 - 2.4 8.1 7.8 0.16 11.8 1.0 2.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family Synaphin PF05835.12 KFP04621.1 - 1.1e-39 135.9 17.5 1.3e-39 135.7 17.5 1.0 1 0 0 1 1 1 1 Synaphin protein LD_cluster2 PF18163.1 KFP04621.1 - 0.094 12.2 3.4 0.13 11.8 3.4 1.1 1 0 0 1 1 1 0 SLOG cluster2 Spt5_N PF11942.8 KFP04621.1 - 0.4 11.7 19.4 0.12 13.4 12.2 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal RR_TM4-6 PF06459.12 KFP04621.1 - 0.71 9.6 11.2 0.93 9.3 11.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Borrelia_P83 PF05262.11 KFP04621.1 - 2.9 6.3 14.1 3.2 6.2 14.1 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4407 PF14362.6 KFP04621.1 - 4.3 6.6 7.2 4.8 6.4 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MDM10 PF12519.8 KFP04621.1 - 4.5 6.0 5.8 5.5 5.7 5.8 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 NODP PF07684.12 KFP04622.1 - 0.071 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 NOTCH protein 6PF2K PF01591.18 KFP04622.1 - 0.11 11.8 0.0 0.25 10.6 0.0 1.7 1 0 0 1 1 1 0 6-phosphofructo-2-kinase P33MONOX PF15302.6 KFP04623.1 - 8.2e-135 449.1 10.8 9.4e-135 448.9 10.8 1.0 1 0 0 1 1 1 1 P33 mono-oxygenase DUF865 PF05906.11 KFP04623.1 - 0.18 11.6 2.5 0.25 11.2 0.2 2.3 2 0 0 2 2 2 0 Herpesvirus-7 repeat of unknown function (DUF865) Nop16 PF09420.10 KFP04624.1 - 7.8e-20 71.8 0.6 3.3e-14 53.4 0.6 2.1 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 Baculo_p33 PF05214.12 KFP04624.1 - 0.0077 16.0 0.9 0.01 15.6 0.9 1.2 1 0 0 1 1 1 1 Baculovirus P33 DUF3781 PF12636.7 KFP04624.1 - 0.22 11.4 1.4 0.39 10.6 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) HIG_1_N PF04588.13 KFP04625.1 - 1.1e-23 83.2 0.8 1.5e-23 82.8 0.8 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF2301 PF10063.9 KFP04625.1 - 0.1 13.0 0.2 0.13 12.7 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized integral membrane protein (DUF2301) Clathrin_lg_ch PF01086.17 KFP04626.1 - 1.6e-44 152.7 6.9 2.2e-44 152.3 6.9 1.2 1 0 0 1 1 1 1 Clathrin light chain Peptidase_M9_N PF08453.10 KFP04626.1 - 0.035 13.8 0.1 0.59 9.8 0.1 2.0 2 0 0 2 2 2 0 Peptidase family M9 N-terminal UBA_4 PF14555.6 KFP04627.1 - 1.3e-07 31.3 0.2 6.9e-07 29.0 0.1 2.0 2 0 0 2 2 2 1 UBA-like domain DUF1682 PF07946.14 KFP04627.1 - 7.9e-06 25.3 8.0 1.1e-05 24.8 8.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) UBX PF00789.20 KFP04627.1 - 1.8e-05 24.8 0.2 7.9e-05 22.8 0.2 2.1 1 1 0 1 1 1 1 UBX domain LIM_bind PF01803.16 KFP04627.1 - 0.035 13.6 0.1 0.044 13.3 0.1 1.3 1 0 0 1 1 1 0 LIM-domain binding protein Thioredoxin_7 PF13899.6 KFP04627.1 - 0.062 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like NARP1 PF12569.8 KFP04627.1 - 0.11 11.4 11.0 0.18 10.7 11.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AAA_23 PF13476.6 KFP04627.1 - 0.16 12.5 11.9 0.34 11.4 11.9 1.6 1 0 0 1 1 1 0 AAA domain Serinc PF03348.15 KFP04627.1 - 0.21 10.5 0.4 0.3 10.0 0.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4366 PF14283.6 KFP04627.1 - 0.44 10.6 3.9 0.74 9.8 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Presenilin PF01080.17 KFP04627.1 - 0.86 8.3 6.7 1.2 7.8 6.7 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 KFP04627.1 - 2.5 6.3 9.6 3.3 5.9 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF5401 PF17380.2 KFP04627.1 - 3 5.8 21.3 4.3 5.3 21.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) MRP-S26 PF14943.6 KFP04627.1 - 6.2 6.7 20.3 11 5.9 20.3 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Connexin PF00029.19 KFP04627.1 - 6.3 6.5 5.3 9.9 5.8 5.3 1.3 1 0 0 1 1 1 0 Connexin Cadherin PF00028.17 KFP04628.1 - 1.4e-98 323.6 16.2 1.2e-16 61.0 0.2 9.7 9 0 0 9 9 9 9 Cadherin domain Cadherin_2 PF08266.12 KFP04628.1 - 4.3e-12 45.7 0.0 0.068 13.0 0.0 5.2 4 0 0 4 4 4 4 Cadherin-like Cadherin_3 PF16184.5 KFP04628.1 - 5.7e-10 39.2 26.4 0.0074 16.3 0.1 8.6 8 2 1 9 9 9 6 Cadherin-like Adeno_E3_CR2 PF02439.15 KFP04628.1 - 6.2 6.7 6.8 20 5.1 6.8 1.8 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Synuclein PF01387.17 KFP04630.1 - 4e-16 59.5 3.3 1.8e-15 57.3 3.3 1.8 1 1 0 1 1 1 1 Synuclein IF4E PF01652.18 KFP04631.1 - 3.2e-56 189.5 0.9 3.7e-56 189.3 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E UPA PF17217.3 KFP04632.1 - 4.1e-69 230.9 0.1 6.9e-69 230.2 0.1 1.4 1 0 0 1 1 1 1 UPA domain ZU5 PF00791.20 KFP04632.1 - 6e-29 100.3 0.0 1.4e-28 99.1 0.0 1.6 1 0 0 1 1 1 1 ZU5 domain Death PF00531.22 KFP04632.1 - 3.3e-12 46.4 0.0 6.4e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Death domain I-set PF07679.16 KFP04632.1 - 9.9e-12 44.8 0.0 2.6e-09 37.0 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP04632.1 - 1.4e-11 44.8 0.1 4.8e-08 33.5 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain TSP_1 PF00090.19 KFP04632.1 - 7.7e-11 42.0 34.4 4.4e-08 33.2 13.7 2.7 2 0 0 2 2 2 2 Thrombospondin type 1 domain ig PF00047.25 KFP04632.1 - 3.2e-05 24.0 0.0 0.01 16.0 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP04632.1 - 3.3e-05 24.1 0.0 0.00036 20.8 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain Hexokinase_2 PF03727.16 KFP04633.1 - 3.1e-149 495.0 1.6 3.9e-82 275.3 0.3 2.1 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.21 KFP04633.1 - 3.5e-121 402.4 0.0 2.9e-65 219.9 0.0 2.3 2 0 0 2 2 2 2 Hexokinase RAP80_UIM PF18282.1 KFP04634.1 - 4.3e-33 112.9 10.4 4.3e-33 112.9 10.4 2.3 2 0 0 2 2 2 1 RAP80 N-terminal ubiquitin interaction motif UIM PF02809.20 KFP04634.1 - 0.012 15.4 8.7 0.2 11.7 0.8 2.9 2 0 0 2 2 2 0 Ubiquitin interaction motif zf-WRNIP1_ubi PF18279.1 KFP04634.1 - 0.018 15.6 0.5 0.051 14.2 0.1 2.1 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Rad50_zn_hook PF04423.14 KFP04634.1 - 0.36 10.7 3.4 12 5.8 0.0 3.6 3 0 0 3 3 3 0 Rad50 zinc hook motif SIR4_SID PF16991.5 KFP04634.1 - 4.2 7.4 7.4 0.56 10.2 2.3 2.0 2 0 0 2 2 2 0 Sir4 SID domain zf-met PF12874.7 KFP04635.1 - 1e-13 51.1 16.4 3.4e-07 30.4 0.5 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP04635.1 - 4.4e-09 36.4 8.5 0.00012 22.3 1.8 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFP04635.1 - 0.0017 18.7 8.8 0.13 12.6 0.9 2.2 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) CTU2 PF10288.9 KFP04635.1 - 0.002 18.3 5.6 0.039 14.2 4.4 2.1 1 1 1 2 2 2 2 Cytoplasmic tRNA 2-thiolation protein 2 zf-U1 PF06220.12 KFP04635.1 - 0.0076 16.0 9.7 0.14 12.0 1.5 3.2 3 0 0 3 3 3 2 U1 zinc finger zf-RING_UBOX PF13445.6 KFP04635.1 - 0.0085 16.1 0.3 0.64 10.1 0.1 2.5 2 0 0 2 2 2 1 RING-type zinc-finger Vps39_2 PF10367.9 KFP04635.1 - 0.023 15.1 1.1 4.2 7.9 0.0 2.3 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-DBF PF07535.12 KFP04635.1 - 0.14 12.3 4.1 0.8 9.9 0.9 2.5 2 0 0 2 2 2 0 DBF zinc finger zf_C2H2_6 PF18450.1 KFP04635.1 - 0.17 11.6 0.6 0.17 11.6 0.6 2.1 2 0 0 2 2 2 0 Zinc Finger domain zf-SCNM1 PF15803.5 KFP04635.1 - 0.25 11.0 2.8 1.9 8.2 0.4 3.3 3 1 0 3 3 3 0 Zinc-finger of sodium channel modifier 1 zf-C2H2_4 PF13894.6 KFP04635.1 - 0.81 10.7 12.1 0.74 10.8 1.2 3.1 3 2 0 3 3 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP04635.1 - 1.1 9.9 11.8 0.65 10.6 1.0 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_9 PF16293.5 KFP04635.1 - 1.4 8.8 4.0 1.2 9.0 0.6 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Pkinase_Tyr PF07714.17 KFP04636.1 - 6.3e-104 346.8 0.0 8.3e-104 346.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP04636.1 - 1.9e-44 152.0 0.0 2.9e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.16 KFP04636.1 - 1.7e-27 95.3 0.0 4e-14 52.4 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP04636.1 - 2.1e-26 92.3 0.0 3.9e-13 49.8 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP04636.1 - 4.7e-21 74.8 0.0 1.5e-10 41.1 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP04636.1 - 3.1e-19 69.1 0.0 3e-10 40.3 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFP04636.1 - 2e-09 37.6 0.1 0.013 15.6 0.1 4.1 2 2 0 2 2 2 2 Immunoglobulin V-set domain Ig_5 PF16681.5 KFP04636.1 - 0.00037 20.8 0.0 1.7 9.1 0.0 2.9 2 0 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFP04636.1 - 0.0071 15.9 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain FGFR3_TM PF18123.1 KFP04636.1 - 0.0084 15.6 0.3 0.014 14.9 0.3 1.4 1 0 0 1 1 1 1 Fibroblast growth factor receptor 3 transmembrane domain Haspin_kinase PF12330.8 KFP04636.1 - 0.039 12.9 0.0 0.074 12.0 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Izumo-Ig PF16706.5 KFP04636.1 - 0.055 13.5 0.0 7.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Pkinase_fungal PF17667.1 KFP04636.1 - 0.066 12.0 0.0 0.098 11.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase C2-set_2 PF08205.12 KFP04636.1 - 0.071 13.2 0.0 0.38 10.9 0.0 2.1 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Kinase-like PF14531.6 KFP04636.1 - 0.093 12.0 0.0 0.25 10.6 0.0 1.6 2 0 0 2 2 2 0 Kinase-like C5HCH PF17982.1 KFP04638.1 - 1.2e-22 79.8 8.6 1.2e-22 79.8 8.6 5.1 3 1 1 4 4 4 1 NSD Cys-His rich domain SET PF00856.28 KFP04638.1 - 1.6e-20 74.2 1.7 1.3e-19 71.2 0.9 2.8 3 1 0 3 3 3 1 SET domain PWWP PF00855.17 KFP04638.1 - 9.2e-19 67.7 0.4 2e-18 66.6 0.4 1.6 1 0 0 1 1 1 1 PWWP domain AWS PF17907.1 KFP04638.1 - 1.9e-17 63.0 6.9 1.9e-17 63.0 6.9 5.6 7 1 0 7 7 7 1 AWS domain PHD PF00628.29 KFP04638.1 - 1.2e-14 53.9 70.2 2e-06 27.6 10.6 6.8 4 2 2 6 6 6 4 PHD-finger PHD_2 PF13831.6 KFP04638.1 - 2.3e-05 23.9 39.1 0.00035 20.0 1.9 5.8 5 0 0 5 5 5 2 PHD-finger Ras PF00071.22 KFP04639.1 - 3e-14 52.9 0.1 4.2e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP04639.1 - 0.019 15.2 0.0 0.047 13.9 0.0 1.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KFP04639.1 - 0.044 13.7 0.0 0.053 13.4 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase PRELI PF04707.14 KFP04640.1 - 4.9e-39 133.7 0.1 7e-39 133.2 0.1 1.2 1 0 0 1 1 1 1 PRELI-like family Hs1pro-1_C PF07014.12 KFP04642.1 - 0.014 14.9 0.1 0.022 14.2 0.1 1.3 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus FAM193_C PF15914.5 KFP04643.1 - 5.3e-29 99.7 0.9 1.1e-28 98.7 0.9 1.6 1 0 0 1 1 1 1 FAM193 family C-terminal NARP1 PF12569.8 KFP04643.1 - 0.057 12.3 5.5 0.089 11.7 5.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DEAD PF00270.29 KFP04644.1 - 1.6e-44 151.8 0.0 7.7e-44 149.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP04644.1 - 5.1e-32 110.5 0.0 3.8e-30 104.5 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain zf-CCHC PF00098.23 KFP04644.1 - 0.0013 18.7 1.5 0.0025 17.8 1.5 1.5 1 0 0 1 1 1 1 Zinc knuckle ResIII PF04851.15 KFP04644.1 - 0.015 15.3 0.0 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 KFP04644.1 - 0.092 12.0 0.0 0.19 11.0 0.0 1.5 1 1 0 1 1 1 0 SecA DEAD-like domain UTP25 PF06862.12 KFP04644.1 - 0.11 11.2 0.0 0.36 9.6 0.0 1.7 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CMS1 PF14617.6 KFP04644.1 - 0.23 10.7 2.1 0.58 9.5 0.0 2.2 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 KFP04644.1 - 0.27 10.4 0.0 0.27 10.4 0.0 2.1 3 0 0 3 3 3 0 ERCC3/RAD25/XPB C-terminal helicase IRS PF02174.17 KFP04645.1 - 5.9e-29 99.9 0.0 1.1e-28 99.0 0.0 1.4 2 0 0 2 2 2 1 PTB domain (IRS-1 type) LIM PF00412.22 KFP04646.1 - 1e-41 140.9 33.0 2.4e-15 56.5 6.5 3.3 3 0 0 3 3 3 3 LIM domain PDZ PF00595.24 KFP04646.1 - 6e-14 52.2 0.0 9.9e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP04646.1 - 1.5e-05 24.8 0.0 3.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP04646.1 - 0.0028 18.0 0.0 0.0048 17.2 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Pkinase PF00069.25 KFP04647.1 - 1.2e-67 228.0 0.0 1.8e-67 227.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP04647.1 - 3e-35 121.7 0.0 4.5e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 KFP04647.1 - 2.3e-20 73.0 0.5 9.6e-20 71.0 0.0 2.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain Pkinase_fungal PF17667.1 KFP04647.1 - 2.6e-05 23.2 0.0 5.1e-05 22.2 0.0 1.3 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KFP04647.1 - 7e-05 22.3 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like 7tm_1 PF00001.21 KFP04648.1 - 5.1e-69 232.5 10.7 6.1e-69 232.3 10.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP04648.1 - 9.8e-07 28.4 4.8 0.0089 15.4 0.6 2.4 2 1 1 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP04648.1 - 0.00018 21.4 1.2 0.00037 20.3 1.2 1.6 1 0 0 1 1 1 1 Olfactory receptor Dr_adhesin PF12393.8 KFP04648.1 - 0.033 14.5 0.5 0.12 12.7 0.5 2.1 1 0 0 1 1 1 0 Dr family adhesin Na_Pi_cotrans PF02690.15 KFP04649.1 - 1e-40 139.1 24.2 1.6e-25 89.8 6.0 2.9 2 1 0 2 2 2 2 Na+/Pi-cotransporter DUF2207 PF09972.9 KFP04649.1 - 5 5.8 8.0 83 1.8 8.0 2.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) RBD PF02196.15 KFP04650.1 - 5.8e-29 100.0 0.2 4.5e-22 77.9 0.0 2.4 2 0 0 2 2 2 2 Raf-like Ras-binding domain RGS PF00615.19 KFP04650.1 - 1.2e-26 93.3 2.4 2.3e-26 92.4 2.4 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain GoLoco PF02188.17 KFP04650.1 - 0.014 14.9 1.3 0.03 13.8 1.3 1.6 1 0 0 1 1 1 0 GoLoco motif Bclx_interact PF08945.10 KFP04650.1 - 0.044 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain SopA PF13981.6 KFP04650.1 - 0.19 12.2 0.2 0.19 12.2 0.2 2.3 2 1 1 3 3 3 0 SopA-like central domain RGS12_us1 PF16613.5 KFP04650.1 - 0.4 11.0 6.1 3.8 7.9 6.1 2.5 1 1 0 1 1 1 0 Unstructured region of RGS12 Arf PF00025.21 KFP04651.1 - 1.8e-67 226.1 0.0 2e-67 226.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFP04651.1 - 1.7e-13 50.9 0.0 2.3e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFP04651.1 - 1.4e-12 47.4 0.0 1.7e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KFP04651.1 - 1.9e-12 47.0 0.0 2.3e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KFP04651.1 - 6e-09 35.6 0.0 7.5e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KFP04651.1 - 7.1e-09 35.3 0.1 5.1e-05 22.6 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KFP04651.1 - 1.9e-08 34.4 0.0 2.7e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP04651.1 - 2.9e-05 23.7 0.0 0.0044 16.6 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 KFP04651.1 - 0.0028 18.2 0.0 0.0045 17.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 KFP04651.1 - 0.0091 15.7 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KFP04651.1 - 0.013 15.4 0.1 3.3 7.6 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 KFP04651.1 - 0.024 14.9 0.0 0.04 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KFP04651.1 - 0.032 13.8 0.1 8.5 5.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 KFP04651.1 - 0.039 13.5 0.0 0.099 12.2 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.27 KFP04651.1 - 0.096 13.2 0.1 0.13 12.8 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 KFP04651.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Lectin_leg-like PF03388.13 KFP04652.1 - 3.5e-89 298.1 0.0 4.1e-89 297.9 0.0 1.0 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 KFP04652.1 - 1.5e-07 31.7 0.0 1.8e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial lectin UL42 PF17638.2 KFP04652.1 - 0.04 13.9 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 HCMV UL42 Glyco_transf_7C PF02709.14 KFP04653.1 - 7.3e-27 92.8 0.2 1.4e-26 92.0 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 KFP04653.1 - 7.6e-22 77.4 0.0 1.2e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.9 KFP04653.1 - 0.08 12.4 0.1 2.6 7.5 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Ribosomal_L7Ae PF01248.26 KFP04654.1 - 9.4e-22 76.6 0.0 1.1e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Kinesin PF00225.23 KFP04655.1 - 1.2e-102 343.3 0.5 1.2e-102 343.3 0.5 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFP04655.1 - 4.8e-18 65.5 2.9 7.9e-16 58.3 0.0 3.3 3 0 0 3 3 3 2 Microtubule binding OmpH PF03938.14 KFP04655.1 - 0.083 13.2 0.1 0.083 13.2 0.1 3.9 2 1 2 4 4 4 0 Outer membrane protein (OmpH-like) MscS_porin PF12795.7 KFP04655.1 - 5.1 6.6 44.7 2.1 7.9 30.9 3.6 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Mtc PF03820.17 KFP04656.1 - 6.9e-154 511.5 0.2 8.2e-154 511.2 0.2 1.1 1 0 0 1 1 1 1 Tricarboxylate carrier 7tm_1 PF00001.21 KFP04657.1 - 2.4e-71 240.2 19.0 2.9e-71 239.9 19.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP04657.1 - 2.1e-09 37.1 17.1 3.6e-09 36.4 17.1 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP04657.1 - 1.1e-06 28.5 14.5 1.1e-06 28.5 14.5 2.3 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF621 PF04789.15 KFP04657.1 - 0.042 13.0 16.6 0.021 14.0 13.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF621) Homeodomain PF00046.29 KFP04658.1 - 3.3e-22 78.1 5.2 4.8e-22 77.6 5.2 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP04658.1 - 0.049 13.5 0.4 0.11 12.4 0.4 1.6 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.8 KFP04658.1 - 0.13 11.8 0.5 0.63 9.6 0.1 2.0 1 1 1 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Calcyon PF06387.11 KFP04659.1 - 8.4e-88 293.1 0.1 9.4e-88 293.0 0.1 1.0 1 0 0 1 1 1 1 D1 dopamine receptor-interacting protein (calcyon) NB PF04159.13 KFP04659.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 NB glycoprotein COMPASS-Shg1 PF05205.12 KFP04660.1 - 1.6e-22 80.1 0.0 2e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 Stanniocalcin PF03298.13 KFP04661.1 - 1.4e-83 279.2 13.7 1.7e-83 278.9 13.7 1.1 1 0 0 1 1 1 1 Stanniocalcin family Homeodomain PF00046.29 KFP04662.1 - 6.9e-20 70.7 4.3 6.9e-20 70.7 4.3 1.8 2 0 0 2 2 2 1 Homeodomain Homez PF11569.8 KFP04662.1 - 0.066 12.7 0.5 0.19 11.3 0.3 1.8 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 KFP04662.1 - 1 9.3 3.4 0.64 10.0 0.1 2.5 3 0 0 3 3 3 0 Homeobox KN domain Sec20 PF03908.13 KFP04663.1 - 3e-33 113.6 3.3 3e-33 113.6 3.3 2.2 2 0 0 2 2 2 1 Sec20 DUF2777 PF10949.8 KFP04663.1 - 0.00038 20.2 3.2 0.00044 20.0 2.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2777) Sec16 PF12932.7 KFP04663.1 - 0.086 13.4 0.2 0.086 13.4 0.2 2.1 2 1 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region 7tm_6 PF02949.20 KFP04663.1 - 0.17 11.0 3.3 0.071 12.2 1.0 1.5 2 0 0 2 2 2 0 7tm Odorant receptor DUF2721 PF11026.8 KFP04663.1 - 0.21 11.5 5.8 1.1 9.1 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) Tombus_P33 PF08500.10 KFP04663.1 - 0.4 10.6 2.4 0.39 10.7 0.4 1.8 2 0 0 2 2 2 0 Tombusvirus p33 Cep57_MT_bd PF06657.13 KFP04663.1 - 1.2 9.6 12.9 0.17 12.4 2.2 2.6 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 ACCA PF03255.14 KFP04663.1 - 1.8 8.4 10.8 0.19 11.6 3.5 2.1 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF1664 PF07889.12 KFP04663.1 - 2.4 8.2 11.7 7.4 6.6 2.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Med9 PF07544.13 KFP04663.1 - 9.6 6.4 16.8 9.2 6.4 1.6 3.1 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 bZIP_1 PF00170.21 KFP04664.1 - 0.0036 17.4 3.3 0.0036 17.4 3.3 2.9 3 0 0 3 3 3 1 bZIP transcription factor BUD22 PF09073.10 KFP04664.1 - 0.17 11.2 13.5 0.32 10.3 13.5 1.5 1 0 0 1 1 1 0 BUD22 bZIP_2 PF07716.15 KFP04664.1 - 2.1 8.5 10.7 0.03 14.4 2.8 2.1 2 0 0 2 2 2 0 Basic region leucine zipper Ribosomal_L26 PF16906.5 KFP04665.1 - 9.1e-44 147.8 5.8 1.2e-43 147.4 5.8 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KFP04665.1 - 6.9e-08 32.2 5.9 2.2e-07 30.6 5.9 2.0 1 1 0 1 1 1 1 KOW motif BLYB PF05289.11 KFP04665.1 - 0.033 14.4 1.9 0.055 13.7 1.9 1.4 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein COPIIcoated_ERV PF07970.12 KFP04666.1 - 1e-36 126.8 0.1 1.8e-36 126.1 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KFP04666.1 - 7.9e-36 122.3 0.0 7.9e-36 122.3 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DSPc PF00782.20 KFP04667.1 - 1.9e-49 166.9 0.0 2.3e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP04667.1 - 3.2e-06 26.9 0.0 3.9e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KFP04667.1 - 0.012 15.9 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 KFP04667.1 - 0.034 14.3 0.0 0.052 13.7 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.12 KFP04667.1 - 0.098 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Neuralized PF07177.12 KFP04668.1 - 6.9e-89 295.5 0.0 1.5e-44 151.6 0.0 2.6 3 0 0 3 3 3 2 Neuralized zf-C3HC4_3 PF13920.6 KFP04668.1 - 5.2e-13 48.6 13.3 1.2e-12 47.4 13.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP04668.1 - 2.5e-05 24.0 12.5 6.2e-05 22.8 12.5 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFP04668.1 - 0.016 15.1 13.9 0.04 13.9 13.9 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFP04668.1 - 0.12 12.3 15.4 0.26 11.2 15.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SH3_1 PF00018.28 KFP04669.1 - 4e-38 128.8 13.4 9.1e-13 47.6 0.1 4.4 4 0 0 4 4 4 4 SH3 domain SH3_9 PF14604.6 KFP04669.1 - 1.3e-34 117.8 5.8 1.3e-12 47.4 0.1 4.5 4 0 0 4 4 4 4 Variant SH3 domain SH3_2 PF07653.17 KFP04669.1 - 3.5e-30 103.5 5.2 6.7e-09 35.3 0.1 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.11 KFP04669.1 - 1.6e-11 44.3 12.8 0.00066 19.9 0.4 4.5 4 0 0 4 4 4 4 Bacterial SH3 domain PX PF00787.24 KFP04669.1 - 1e-06 28.7 2.2 3.1e-06 27.1 0.1 2.4 2 0 0 2 2 2 1 PX domain SH3_4 PF06347.13 KFP04669.1 - 0.0007 19.4 0.8 0.0007 19.4 0.8 3.9 4 0 0 4 4 4 2 Bacterial SH3 domain UBD PF16455.5 KFP04670.1 - 4.4e-39 132.9 0.0 6.1e-39 132.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 KFP04670.1 - 4.1e-14 52.1 0.0 6.5e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KFP04670.1 - 1.2e-05 25.0 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TPR_12 PF13424.6 KFP04671.1 - 3.5e-12 46.4 39.1 4e-05 23.8 3.0 7.8 6 1 1 7 7 7 5 Tetratricopeptide repeat SH3_2 PF07653.17 KFP04671.1 - 2.3e-10 40.0 0.1 5.7e-05 22.7 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KFP04671.1 - 1.9e-08 33.8 0.2 0.00074 19.1 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KFP04671.1 - 6.7e-08 32.3 0.3 0.0064 16.3 0.0 3.3 3 0 0 3 3 3 2 Variant SH3 domain SNAP PF14938.6 KFP04671.1 - 2.3e-06 27.3 2.4 6.7e-06 25.7 0.8 2.5 3 0 0 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_1 PF00515.28 KFP04671.1 - 4e-05 23.3 31.1 0.0015 18.2 0.0 8.8 8 2 1 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFP04671.1 - 0.037 14.1 0.1 0.037 14.1 0.1 10.9 11 1 1 12 12 12 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFP04671.1 - 0.19 12.1 39.1 2.8 8.4 0.5 11.0 12 1 1 13 13 13 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP04671.1 - 3.7 7.8 20.0 35 4.8 0.1 8.4 8 1 1 9 9 9 0 Tetratricopeptide repeat AbLIM_anchor PF16182.5 KFP04672.1 - 8.2e-87 292.5 25.7 1.2e-72 245.8 4.1 3.1 1 1 2 3 3 3 3 Putative adherens-junction anchoring region of AbLIM LIM PF00412.22 KFP04672.1 - 6.1e-43 144.9 48.3 2e-14 53.6 3.8 4.8 4 1 1 5 5 5 4 LIM domain VHP PF02209.19 KFP04672.1 - 5.2e-16 58.4 0.3 2.8e-15 56.1 0.8 2.0 2 0 0 2 2 2 1 Villin headpiece domain PH PF00169.29 KFP04673.1 - 1.7e-20 73.5 0.1 1.7e-09 38.1 0.1 2.5 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KFP04673.1 - 5.2e-05 23.6 1.0 0.071 13.5 0.0 3.6 2 1 0 2 2 2 2 Pleckstrin homology domain Sharpin_PH PF16764.5 KFP04673.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 Sharpin PH domain tify PF06200.14 KFP04673.1 - 0.2 11.0 0.2 0.83 9.0 0.2 2.0 2 0 0 2 2 2 0 tify domain PH_9 PF15410.6 KFP04673.1 - 0.22 11.9 2.1 30 5.0 0.1 3.6 3 2 0 3 3 3 0 Pleckstrin homology domain Spc7 PF08317.11 KFP04673.1 - 2.9 6.7 12.7 5.2 5.9 12.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0449 PF15136.6 KFP04673.1 - 3.6 8.1 7.2 5.9 7.4 2.3 2.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 GrpE PF01025.19 KFP04674.1 - 2.5e-41 141.1 0.0 2.9e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 GrpE CLZ PF16526.5 KFP04674.1 - 0.018 15.4 0.9 0.4 11.1 0.1 2.1 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2408 PF10303.9 KFP04674.1 - 0.018 15.6 0.2 0.026 15.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Prenylcys_lyase PF07156.14 KFP04675.1 - 3.2e-148 493.7 0.0 3.8e-148 493.4 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 KFP04675.1 - 3.4e-08 33.6 0.2 9.3e-08 32.2 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KFP04675.1 - 1.4e-05 24.6 0.0 2.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KFP04675.1 - 0.016 15.2 0.1 0.033 14.2 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding DAO PF01266.24 KFP04675.1 - 0.086 12.4 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase IL17 PF06083.11 KFP04676.1 - 2.2e-27 95.4 1.8 3.4e-27 94.7 1.8 1.3 1 0 0 1 1 1 1 Interleukin-17 Pkinase PF00069.25 KFP04677.1 - 4.4e-19 68.9 0.0 5.6e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KFP04677.1 - 1.8e-10 40.2 0.1 1.8e-10 40.2 0.1 1.4 2 0 0 2 2 2 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KFP04677.1 - 1.2e-09 37.8 0.0 1.4e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KFP04677.1 - 0.017 14.1 0.1 0.028 13.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KFP04677.1 - 0.071 12.4 1.1 0.13 11.6 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-B_box PF00643.24 KFP04678.1 - 4.1e-10 39.6 27.9 3.4e-09 36.7 8.1 3.9 3 1 1 4 4 4 3 B-box zinc finger zf-UBR PF02207.20 KFP04678.1 - 0.023 14.9 2.3 0.023 14.9 2.3 2.7 3 1 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) zf-UBP_var PF17807.1 KFP04678.1 - 0.054 13.3 5.4 0.091 12.5 0.5 2.5 2 0 0 2 2 2 0 Variant UBP zinc finger Papo_T_antigen PF02380.15 KFP04678.1 - 0.85 9.8 12.9 0.078 13.1 3.8 2.3 2 0 0 2 2 2 0 T-antigen specific domain CTU2 PF10288.9 KFP04678.1 - 6.6 7.0 16.7 0.15 12.3 5.0 2.8 1 1 1 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-B_box PF00643.24 KFP04679.1 - 0.00088 19.4 7.8 0.00088 19.4 7.8 3.7 3 1 0 3 3 3 1 B-box zinc finger FAM91_C PF14648.6 KFP04679.1 - 0.096 11.5 0.9 0.1 11.4 0.9 1.1 1 0 0 1 1 1 0 FAM91 C-terminus Sulfate_transp PF00916.20 KFP04680.1 - 2.3e-130 434.8 18.5 3.3e-130 434.2 18.5 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFP04680.1 - 2.6e-28 98.0 0.0 4.7e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain Sulfate_transp PF00916.20 KFP04681.1 - 1.3e-112 376.3 16.8 1.8e-112 375.8 16.8 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFP04681.1 - 6.6e-25 87.0 0.0 1.1e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain PAP2 PF01569.21 KFP04681.1 - 0.26 11.1 0.0 0.26 11.1 0.0 3.9 3 2 1 4 4 4 0 PAP2 superfamily 7tm_1 PF00001.21 KFP04682.1 - 5.4e-68 229.2 13.2 7.1e-68 228.8 13.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP04682.1 - 0.00019 21.3 11.9 0.00034 20.5 11.9 1.3 1 0 0 1 1 1 1 Olfactory receptor DUF621 PF04789.15 KFP04682.1 - 0.087 12.0 13.2 0.13 11.4 13.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF621) Git3 PF11710.8 KFP04682.1 - 1.6 8.5 15.0 4.8 6.9 15.0 1.8 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 F-box PF00646.33 KFP04683.1 - 0.0002 21.2 0.1 0.00058 19.7 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFP04683.1 - 0.0026 17.6 0.3 0.0064 16.4 0.3 1.6 1 0 0 1 1 1 1 F-box-like IL12p40_C PF10420.9 KFP04684.1 - 1.7e-23 82.9 2.2 2.3e-23 82.5 0.7 2.0 2 0 0 2 2 2 1 Cytokine interleukin-12p40 C-terminus Ig_5 PF16681.5 KFP04684.1 - 1.3e-05 25.5 0.5 0.00026 21.3 0.0 2.9 3 0 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain ig PF00047.25 KFP04684.1 - 6.3e-05 23.1 0.9 0.0032 17.6 0.3 3.3 2 1 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 KFP04684.1 - 0.00041 20.9 0.5 0.00041 20.9 0.5 3.3 3 1 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 KFP04684.1 - 0.00051 20.3 3.3 0.0018 18.6 0.2 3.0 1 1 3 4 4 4 1 Immunoglobulin domain Ig_4 PF16680.5 KFP04684.1 - 0.0022 18.2 0.7 0.12 12.6 0.2 2.9 1 1 1 2 2 2 1 T-cell surface glycoprotein CD3 delta chain SH2 PF00017.24 KFP04684.1 - 0.0042 17.1 0.0 0.11 12.6 0.0 2.7 2 1 0 2 2 2 1 SH2 domain Ig_6 PF18452.1 KFP04684.1 - 0.015 14.8 0.1 1.9 8.1 0.0 2.7 2 0 0 2 2 2 0 Immunoglobulin domain NtCtMGAM_N PF16863.5 KFP04684.1 - 0.025 14.8 0.0 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase V-set PF07686.17 KFP04684.1 - 0.026 14.7 4.9 0.31 11.2 0.4 3.4 3 1 1 4 4 3 0 Immunoglobulin V-set domain I-set PF07679.16 KFP04684.1 - 0.08 13.0 2.2 3.9 7.6 0.2 3.9 3 2 2 5 5 5 0 Immunoglobulin I-set domain DUF5412 PF17428.2 KFP04684.1 - 0.09 12.6 0.4 11 5.9 0.1 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5412) Neur_chan_memb PF02932.16 KFP04685.1 - 3.7e-41 141.7 6.4 3.5e-38 132.0 1.1 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFP04685.1 - 8.6e-39 133.2 1.9 1.2e-38 132.8 1.9 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.23 KFP04686.1 - 5.9e-51 173.0 0.0 7.7e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP04686.1 - 1.5e-38 133.2 4.5 5.5e-31 108.4 5.0 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFP04687.1 - 1.9e-50 171.3 0.0 2.5e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP04687.1 - 2.4e-39 135.8 3.5 6.9e-35 121.2 1.9 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Cyclin_N PF00134.23 KFP04687.1 - 0.038 13.7 0.4 0.067 12.9 0.4 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain Mito_fiss_reg PF05308.11 KFP04687.1 - 0.062 13.4 3.1 0.096 12.8 3.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF4396 PF14342.6 KFP04687.1 - 0.25 11.7 10.2 0.14 12.5 5.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4396) CAP_N PF01213.19 KFP04687.1 - 0.44 10.0 7.4 0.69 9.3 7.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 KFP04687.1 - 0.94 9.5 8.3 2 8.5 8.3 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Neur_chan_LBD PF02931.23 KFP04688.1 - 1.2e-49 168.7 0.0 2.1e-49 167.9 0.0 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP04688.1 - 1.1e-47 163.1 0.8 5.3e-47 160.9 0.8 1.8 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region PhoLip_ATPase_C PF16212.5 KFP04689.1 - 3e-79 266.3 25.9 3e-79 266.3 25.9 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFP04689.1 - 3.7e-21 74.6 0.2 3.7e-21 74.6 0.2 2.4 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFP04689.1 - 6.6e-13 49.4 0.1 1.4e-06 28.7 0.1 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFP04689.1 - 6.5e-09 35.8 0.0 4.7e-08 33.0 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFP04689.1 - 4.7e-06 26.2 0.0 1.7e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFP04689.1 - 0.0052 16.5 1.7 0.012 15.3 0.2 2.3 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Securin PF04856.13 KFP04690.1 - 4.2e-14 53.1 0.2 5.1e-14 52.8 0.2 1.1 1 0 0 1 1 1 1 Securin sister-chromatid separation inhibitor DUF3881 PF12997.7 KFP04690.1 - 0.045 13.0 0.0 0.055 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) Slu7 PF11708.8 KFP04691.1 - 4.1e-109 364.5 12.0 4.1e-109 364.5 12.0 2.7 3 1 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 KFP04691.1 - 0.02 14.6 0.1 0.04 13.6 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle C1q PF00386.21 KFP04692.1 - 1.1e-38 132.3 0.0 1.4e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFP04692.1 - 1.2e-17 63.3 62.0 9.6e-10 38.1 34.4 2.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) BclA_C PF18573.1 KFP04692.1 - 0.0047 16.8 0.0 0.0067 16.3 0.0 1.2 1 0 0 1 1 1 1 BclA C-terminal domain Cyclin_C PF02984.19 KFP04693.1 - 1.8e-21 76.4 4.1 1.3e-18 67.2 0.3 2.4 2 1 0 2 2 2 2 Cyclin, C-terminal domain Cyclin_N PF00134.23 KFP04693.1 - 1.9e-18 66.4 1.4 3.9e-18 65.4 1.4 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 KFP04693.1 - 0.25 11.4 0.0 0.25 11.4 0.0 1.7 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Lipocalin_7 PF14651.6 KFP04694.1 - 6.6e-61 203.9 1.6 7.4e-61 203.7 1.6 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family PWWP PF00855.17 KFP04695.1 - 5.2e-12 46.0 0.0 5.2e-12 46.0 0.0 3.2 2 1 0 2 2 2 1 PWWP domain TPR_1 PF00515.28 KFP04696.1 - 7.6e-24 82.5 0.8 3.3e-07 29.8 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFP04696.1 - 2.2e-18 64.8 1.0 2.1e-05 24.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFP04696.1 - 8.7e-13 47.7 2.1 0.00049 19.7 0.1 3.5 2 1 1 3 3 3 3 TPR repeat TPR_12 PF13424.6 KFP04696.1 - 1.3e-10 41.4 0.3 6e-05 23.2 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP04696.1 - 1.4e-10 40.6 7.9 0.00064 19.7 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFP04696.1 - 4.4e-08 33.5 2.8 6.7e-06 26.5 0.5 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFP04696.1 - 8.4e-07 28.5 2.2 0.0019 17.4 0.2 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFP04696.1 - 1.2e-06 28.5 1.3 1.3e-05 25.3 1.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFP04696.1 - 2e-06 28.1 1.1 0.063 14.1 0.3 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFP04696.1 - 3.4e-05 24.4 0.3 0.03 15.0 0.2 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFP04696.1 - 9.8e-05 22.1 0.4 0.4 10.8 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFP04696.1 - 0.0001 22.7 0.6 0.0054 17.3 0.1 3.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFP04696.1 - 0.001 19.3 4.8 0.0041 17.4 0.1 4.0 5 1 0 5 5 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFP04696.1 - 0.018 14.9 0.5 7.2 6.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 KFP04696.1 - 0.039 13.7 6.2 0.23 11.1 1.0 2.9 3 0 0 3 3 3 0 26S proteasome subunit RPN7 DUF3856 PF12968.7 KFP04696.1 - 0.047 13.8 0.3 4.1 7.5 0.3 2.9 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) MG2 PF01835.19 KFP04696.1 - 0.14 12.6 0.0 0.39 11.2 0.0 1.9 2 0 0 2 2 1 0 MG2 domain Fis1_TPR_C PF14853.6 KFP04696.1 - 0.15 12.2 1.5 6.2 7.0 0.1 3.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF3870 PF12986.7 KFP04696.1 - 0.16 12.2 0.0 0.41 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) MAS20 PF02064.15 KFP04696.1 - 4.3 7.4 8.3 0.35 11.0 1.3 2.4 2 0 0 2 2 2 0 MAS20 protein import receptor 7tm_1 PF00001.21 KFP04697.1 - 1.1e-80 270.8 6.9 1.4e-80 270.4 6.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP04697.1 - 2.8e-16 59.7 3.7 6.8e-16 58.4 3.7 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP04697.1 - 1.1e-05 25.3 11.3 1.3e-05 25.1 4.5 2.7 3 0 0 3 3 3 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP04697.1 - 1.5e-05 24.8 10.5 1.5e-05 24.8 10.5 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFP04697.1 - 0.00051 19.5 0.3 0.00051 19.5 0.3 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv Shisa PF13908.6 KFP04697.1 - 0.18 12.1 0.8 8.7 6.5 1.0 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF1980 PF09323.10 KFP04697.1 - 0.37 10.7 0.0 0.37 10.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF1949 PF09186.11 KFP04698.1 - 0.25 11.3 2.0 0.44 10.4 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1949) zf-CCCH_6 PF18585.1 KFP04698.1 - 1.3 9.0 4.7 7.3 6.5 0.2 4.1 3 0 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 DOCK_N PF16172.5 KFP04699.1 - 6.5e-114 380.8 0.1 1.2e-113 379.9 0.1 1.5 1 0 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 KFP04699.1 - 1.2e-99 334.4 7.3 1.2e-99 334.4 7.3 2.7 2 1 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 KFP04699.1 - 9.3e-58 195.3 0.0 9.6e-57 191.9 0.0 2.5 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins SH3_1 PF00018.28 KFP04699.1 - 8.5e-06 25.3 0.0 2e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP04699.1 - 5.2e-05 23.0 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP04699.1 - 0.00083 19.0 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain FliX PF10768.9 KFP04699.1 - 0.13 12.8 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 Class II flagellar assembly regulator DUF1539 PF07560.11 KFP04699.1 - 1.6 8.8 6.5 0.63 10.1 1.1 3.3 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) FAM196 PF15265.6 KFP04700.1 - 9.8e-138 460.7 21.7 1.1e-137 460.5 21.7 1.0 1 0 0 1 1 1 1 FAM196 family Forkhead PF00250.18 KFP04701.1 - 7.7e-40 135.0 0.0 9.1e-40 134.8 0.0 1.1 1 0 0 1 1 1 1 Forkhead domain SH2 PF00017.24 KFP04702.1 - 2.1e-13 50.2 0.0 3.7e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SAM_2 PF07647.17 KFP04702.1 - 1e-10 41.6 0.0 1.6e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFP04702.1 - 0.0054 17.2 0.0 0.0091 16.4 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) YL1 PF05764.13 KFP04702.1 - 0.51 10.4 6.3 0.78 9.8 6.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein NOA36 PF06524.12 KFP04702.1 - 2.6 7.3 6.8 3.7 6.8 6.8 1.2 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 KFP04702.1 - 7.6 5.9 8.6 11 5.4 8.6 1.1 1 0 0 1 1 1 0 SDA1 CaKB PF03185.15 KFP04703.1 - 8.9e-72 240.9 0.6 1e-71 240.7 0.6 1.0 1 0 0 1 1 1 1 Calcium-activated potassium channel, beta subunit zf-LITAF-like PF10601.9 KFP04703.1 - 0.93 9.8 4.3 2.6 8.4 0.6 2.3 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain EF-hand_7 PF13499.6 KFP04704.1 - 4e-24 84.8 1.6 1.7e-18 66.8 0.3 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFP04704.1 - 5.7e-18 63.1 6.2 2.5e-07 29.8 0.2 4.0 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFP04704.1 - 8e-16 56.6 5.5 0.00029 20.5 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KFP04704.1 - 1.5e-15 56.7 3.4 5.3e-05 23.0 0.0 3.5 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KFP04704.1 - 2.1e-12 46.0 4.1 2.9e-05 23.4 0.1 3.7 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.9 KFP04704.1 - 2.7e-06 27.7 1.2 0.00054 20.3 1.0 3.0 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFP04704.1 - 0.0015 18.5 1.6 0.068 13.1 0.1 2.8 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFP04704.1 - 0.0025 18.1 0.1 7.4 7.0 0.0 3.7 4 0 0 4 4 4 1 EF-hand domain Dockerin_1 PF00404.18 KFP04704.1 - 0.095 12.9 0.6 1.2 9.4 0.5 2.3 1 1 1 2 2 2 0 Dockerin type I domain Troponin PF00992.20 KFP04704.1 - 0.14 12.5 0.1 0.4 11.0 0.1 1.8 1 1 1 2 2 2 0 Troponin Caleosin PF05042.13 KFP04704.1 - 0.32 10.9 3.2 6.2 6.7 0.1 2.9 2 1 0 2 2 2 0 Caleosin related protein Neur_chan_LBD PF02931.23 KFP04705.1 - 9.2e-46 156.0 0.5 1.4e-45 155.4 0.1 1.4 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP04705.1 - 7.1e-24 85.2 9.7 1.3e-21 77.7 3.8 2.1 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region I-set PF07679.16 KFP04706.1 - 1.4e-14 53.9 0.0 2.2e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP04706.1 - 2e-13 50.8 0.2 5.1e-13 49.4 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin domain IGFBP PF00219.18 KFP04706.1 - 8.3e-07 29.6 21.2 8.3e-07 29.6 21.2 2.2 2 0 0 2 2 2 1 Insulin-like growth factor binding protein ig PF00047.25 KFP04706.1 - 8.1e-06 25.9 0.0 1.9e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Kazal_2 PF07648.15 KFP04706.1 - 0.0007 19.7 2.5 0.0007 19.7 2.5 2.7 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Ig_2 PF13895.6 KFP04706.1 - 0.002 18.4 0.0 0.0039 17.5 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP04706.1 - 0.0028 17.8 0.0 0.0059 16.8 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain Kazal_1 PF00050.21 KFP04706.1 - 0.013 15.5 14.8 0.078 13.0 14.8 2.4 1 1 0 1 1 1 0 Kazal-type serine protease inhibitor domain Nucleoplasmin PF03066.15 KFP04707.1 - 8.3e-37 125.8 0.0 2e-36 124.6 0.0 1.7 1 0 0 1 1 1 1 Nucleoplasmin/nucleophosmin domain NPM1-C PF16276.5 KFP04707.1 - 1.4e-28 98.6 0.7 3.5e-28 97.3 0.7 1.7 1 0 0 1 1 1 1 Nucleophosmin C-terminal domain TFIIF_alpha PF05793.12 KFP04707.1 - 0.00046 18.9 17.4 0.0005 18.8 17.4 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 KFP04707.1 - 0.0015 16.9 18.1 0.0021 16.4 18.1 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 KFP04707.1 - 0.0024 17.4 14.9 0.0033 16.9 14.9 1.2 1 0 0 1 1 1 1 SDA1 NOA36 PF06524.12 KFP04707.1 - 0.082 12.2 18.3 0.17 11.2 18.3 1.4 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 KFP04707.1 - 0.35 9.1 14.5 0.48 8.6 14.5 1.2 1 0 0 1 1 1 0 CDC45-like protein GCIP PF13324.6 KFP04707.1 - 0.38 10.3 6.2 0.87 9.1 6.2 1.7 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF2922 PF11148.8 KFP04707.1 - 0.86 9.4 3.1 0.58 9.9 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2922) SLAIN PF15301.6 KFP04707.1 - 1 8.5 9.3 2.2 7.4 8.9 1.7 1 1 0 1 1 1 0 SLAIN motif-containing family DNA_pol_phi PF04931.13 KFP04707.1 - 1.4 6.9 21.4 2.1 6.3 21.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi XAP5 PF04921.14 KFP04707.1 - 3.4 7.4 12.3 8.7 6.1 12.3 1.7 1 0 0 1 1 1 0 XAP5, circadian clock regulator RRN3 PF05327.11 KFP04707.1 - 8.7 4.8 14.4 13 4.1 14.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SURF2 PF05477.11 KFP04707.1 - 9.8 5.8 16.8 16 5.1 16.8 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) FGF PF00167.18 KFP04708.1 - 1.1e-42 145.0 0.1 1.6e-42 144.6 0.1 1.2 1 0 0 1 1 1 1 Fibroblast growth factor WD40 PF00400.32 KFP04709.1 - 6.7e-40 134.4 17.9 6.7e-07 29.9 0.2 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat Beta-TrCP_D PF12125.8 KFP04709.1 - 9.9e-26 89.4 2.3 2.1e-25 88.3 2.3 1.6 1 0 0 1 1 1 1 D domain of beta-TrCP ANAPC4_WD40 PF12894.7 KFP04709.1 - 3.6e-11 43.2 2.7 0.0095 16.2 0.1 4.6 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 KFP04709.1 - 1.1e-09 38.0 0.1 2.6e-09 36.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFP04709.1 - 1.4e-06 28.0 0.0 4.2e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 KFP04709.1 - 1.8e-06 27.5 0.1 0.0082 15.5 0.4 2.5 1 1 1 2 2 2 2 WD40-like domain Nup160 PF11715.8 KFP04709.1 - 7.8e-05 21.5 10.3 0.095 11.3 0.2 4.5 3 2 3 6 6 6 2 Nucleoporin Nup120/160 DUF5046 PF16465.5 KFP04709.1 - 0.0092 15.5 0.2 0.91 8.9 0.2 3.2 1 1 2 3 3 3 1 Domain of unknown function (DUF5046) eIF2A PF08662.11 KFP04709.1 - 0.022 14.7 0.0 4.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF4508 PF14969.6 KFP04709.1 - 0.09 13.0 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) DUF1513 PF07433.11 KFP04709.1 - 0.12 11.5 0.0 1.2 8.1 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1513) Prot_ATP_ID_OB PF16450.5 KFP04709.1 - 0.14 12.1 0.2 15 5.7 0.0 3.2 2 1 0 2 2 2 0 Proteasomal ATPase OB C-terminal domain eRF1_2 PF03464.15 KFP04710.1 - 1.4e-46 158.1 0.1 2.4e-46 157.3 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KFP04710.1 - 4.3e-39 133.5 0.3 9.3e-39 132.4 0.3 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KFP04710.1 - 3.7e-18 65.8 0.0 7.1e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 KFP04710.1 - 8.8e-11 42.2 0.1 1.3e-10 41.7 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 KFP04710.1 - 7.1e-09 36.0 0.0 1.2e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Ribosomal_L7Ae PF01248.26 KFP04710.1 - 0.011 15.5 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF4825 PF16107.5 KFP04710.1 - 0.12 12.5 0.1 3.9 7.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4825) RmlD_sub_bind PF04321.17 KFP04711.1 - 3.4e-84 282.3 0.0 3.9e-84 282.1 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KFP04711.1 - 2.5e-21 76.3 0.0 3.2e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFP04711.1 - 1.3e-09 37.6 0.1 7.1e-07 28.6 0.1 2.7 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KFP04711.1 - 9.7e-09 35.1 0.0 3.4e-08 33.3 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KFP04711.1 - 4.9e-06 25.9 0.0 0.0016 17.7 0.0 2.7 2 1 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 KFP04711.1 - 0.00091 18.3 0.1 0.0055 15.7 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KFP04711.1 - 0.063 12.7 0.0 1.9 7.9 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase HMMR_N PF15905.5 KFP04712.1 - 4e-95 319.1 60.9 4e-95 319.1 60.9 4.4 2 1 3 5 5 5 1 Hyaluronan mediated motility receptor N-terminal HMMR_C PF15908.5 KFP04712.1 - 4.1e-60 202.6 19.0 4.1e-60 202.6 19.0 6.2 2 1 4 6 6 6 1 Hyaluronan mediated motility receptor C-terminal PLAC9 PF15205.6 KFP04712.1 - 2 8.9 9.4 3.8 8.0 0.4 4.0 3 0 0 3 3 3 0 Placenta-specific protein 9 Cyclin_N PF00134.23 KFP04713.1 - 3.7e-22 78.4 0.2 8.5e-22 77.2 0.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP04713.1 - 0.033 14.3 2.5 0.058 13.5 1.2 2.0 2 0 0 2 2 2 0 Cyclin, C-terminal domain RD3 PF14473.6 KFP04713.1 - 0.046 13.6 0.7 0.25 11.2 0.1 2.2 1 1 1 2 2 2 0 RD3 protein tRNA-synt_1d PF00750.19 KFP04714.1 - 5.2e-158 525.5 0.0 7.1e-158 525.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) Arg_tRNA_synt_N PF03485.16 KFP04714.1 - 8e-22 77.6 0.1 3.3e-21 75.7 0.0 2.1 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain DALR_1 PF05746.15 KFP04714.1 - 1.3e-20 73.8 0.1 3.3e-20 72.4 0.1 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain CCDC14 PF15254.6 KFP04714.1 - 0.041 12.5 0.5 0.069 11.8 0.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 tRNA-synt_1e PF01406.19 KFP04714.1 - 0.11 11.9 0.1 0.46 9.8 0.0 2.1 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1 PF00133.22 KFP04714.1 - 0.11 10.7 0.0 0.19 9.9 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) WW PF00397.26 KFP04715.1 - 1.4e-09 37.8 0.2 3.1e-09 36.8 0.2 1.6 1 0 0 1 1 1 1 WW domain C2 PF00168.30 KFP04715.1 - 8.9e-05 22.7 0.0 0.00028 21.1 0.0 1.9 1 0 0 1 1 1 1 C2 domain Sec2p PF06428.11 KFP04715.1 - 0.013 15.5 1.5 0.013 15.5 1.5 5.7 6 1 0 6 6 6 0 GDP/GTP exchange factor Sec2p DUF3138 PF11336.8 KFP04715.1 - 0.27 9.8 1.9 0.27 9.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Ten_N PF06484.12 KFP04717.1 - 4.3e-33 115.7 3.1 4.8e-33 115.6 3.1 1.0 1 0 0 1 1 1 1 Teneurin Intracellular Region OSK PF17182.4 KFP04718.1 - 0.0011 18.3 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 OSK domain Lipase_GDSL_2 PF13472.6 KFP04718.1 - 0.0024 18.3 0.0 0.006 17.0 0.0 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF1192 PF06698.11 KFP04718.1 - 0.24 11.5 1.0 0.68 10.0 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Perilipin PF03036.16 KFP04720.1 - 3.3e-42 144.9 1.2 3.6e-42 144.8 1.2 1.0 1 0 0 1 1 1 1 Perilipin family DUF5536 PF17688.1 KFP04720.1 - 0.021 14.7 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5536) Snf7 PF03357.21 KFP04721.1 - 3.5e-46 156.9 8.8 3.9e-46 156.8 8.8 1.0 1 0 0 1 1 1 1 Snf7 SYF2 PF08231.12 KFP04721.1 - 0.00033 21.1 1.2 0.00041 20.8 1.2 1.2 1 0 0 1 1 1 1 SYF2 splicing factor ABC_tran_CTD PF16326.5 KFP04721.1 - 1.1 9.5 13.2 6.7 7.0 0.5 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain zf-C2H2 PF00096.26 KFP04722.1 - 8.2e-34 114.2 113.4 4.9e-05 23.6 1.6 12.4 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP04722.1 - 1.6e-31 107.3 95.3 7e-09 35.7 0.0 13.2 13 0 0 13 13 13 10 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP04722.1 - 1.3e-27 94.0 101.6 0.00083 20.0 0.4 12.5 12 0 0 12 12 12 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP04722.1 - 4.2e-11 42.8 84.8 0.017 15.4 3.2 11.8 11 1 1 12 12 12 9 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP04722.1 - 4.8e-05 23.3 2.4 4.8e-05 23.3 2.4 11.8 12 0 0 12 12 12 5 C2H2-type zinc finger BolA PF01722.18 KFP04722.1 - 0.00013 22.2 15.3 0.0082 16.4 0.1 5.1 4 2 1 5 5 5 2 BolA-like protein zf-C2H2_2 PF12756.7 KFP04722.1 - 0.00085 19.6 67.7 0.23 11.8 0.8 8.6 2 2 7 9 9 9 5 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 KFP04722.1 - 0.0012 18.6 9.7 1.2 9.0 0.4 3.8 3 0 0 3 3 3 3 GAGA factor zf-H2C2_5 PF13909.6 KFP04722.1 - 0.019 14.7 0.1 0.019 14.7 0.1 10.6 10 2 0 10 10 10 0 C2H2-type zinc-finger domain zf-met PF12874.7 KFP04722.1 - 0.075 13.4 74.9 0.62 10.5 1.2 11.3 12 0 0 12 12 12 0 Zinc-finger of C2H2 type zf-Paramyx-P PF13008.7 KFP04722.1 - 0.22 11.0 4.2 0.42 10.1 1.2 3.0 2 0 0 2 2 2 0 Zinc-binding domain of Paramyxoviridae V protein zf-CHCC PF10276.9 KFP04722.1 - 2.1 8.4 8.2 18 5.5 0.1 4.7 4 0 0 4 4 4 0 Zinc-finger domain Tim17 PF02466.19 KFP04723.1 - 2.1e-11 44.2 0.3 3.7e-11 43.4 0.3 1.4 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family E2F_CC-MB PF16421.5 KFP04724.1 - 1.3e-19 70.4 0.0 2.1e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain EF-hand_5 PF13202.6 KFP04725.1 - 3.8e-07 29.3 4.1 1.6e-05 24.2 0.9 2.6 1 1 1 2 2 2 2 EF hand EF-hand_1 PF00036.32 KFP04725.1 - 1.2e-06 27.6 2.4 1.1e-05 24.6 0.7 2.5 1 1 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KFP04725.1 - 3.3e-05 23.5 1.1 0.0021 17.9 0.4 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 KFP04725.1 - 7.3e-05 22.5 2.3 0.00022 21.0 0.4 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 KFP04725.1 - 0.0013 19.1 0.7 0.0034 17.8 0.3 1.9 2 0 0 2 2 2 1 EF-hand domain pair ABM PF03992.16 KFP04725.1 - 0.0026 17.9 0.1 0.0069 16.5 0.0 1.7 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase Spore_III_AB PF09548.10 KFP04725.1 - 0.081 13.0 0.2 0.13 12.3 0.2 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) PH_17 PF18012.1 KFP04727.1 - 5.6e-26 90.0 0.1 1.1e-25 89.2 0.1 1.5 1 0 0 1 1 1 1 PH domain PDZ PF00595.24 KFP04727.1 - 1.6e-14 54.0 0.1 3.2e-14 53.0 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP04727.1 - 1.8e-05 24.5 0.0 3.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 KFP04727.1 - 0.00024 21.6 0.0 0.13 12.8 0.0 2.3 2 0 0 2 2 2 2 PH domain PDZ_2 PF13180.6 KFP04727.1 - 0.002 18.4 0.1 0.0044 17.3 0.1 1.5 1 0 0 1 1 1 1 PDZ domain SRCR PF00530.18 KFP04729.1 - 4.8e-122 399.3 39.6 2e-31 108.4 1.9 4.1 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFP04729.1 - 2.8e-13 50.2 18.9 0.0066 17.0 0.2 4.3 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFP04729.1 - 6.4e-05 23.4 2.6 13 6.3 0.1 4.3 4 0 0 4 4 4 2 Hepsin, SRCR domain Ribosomal_S27e PF01667.17 KFP04729.1 - 0.41 10.4 2.3 2.4 8.0 0.1 2.8 3 0 0 3 3 3 0 Ribosomal protein S27 SRCR PF00530.18 KFP04730.1 - 1.1e-126 414.1 43.1 4.4e-33 113.8 6.1 4.1 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFP04730.1 - 1.4e-20 73.6 13.7 0.00017 22.0 0.3 4.4 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFP04730.1 - 7.9e-08 32.8 6.2 0.78 10.3 0.0 4.3 4 0 0 4 4 4 4 Hepsin, SRCR domain PEP-utilizers PF00391.23 KFP04730.1 - 0.028 14.2 0.1 31 4.4 0.0 3.4 3 0 0 3 3 3 0 PEP-utilising enzyme, mobile domain zf-H2C2_2 PF13465.6 KFP04731.1 - 7.3e-43 143.1 48.8 8.8e-09 35.4 0.3 6.7 7 0 0 7 7 6 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFP04731.1 - 6.6e-36 120.8 41.8 6.4e-07 29.5 1.7 6.1 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP04731.1 - 1.1e-20 72.5 43.7 0.00019 22.0 0.4 6.1 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP04731.1 - 8.3e-16 57.8 20.1 0.012 15.9 0.0 6.2 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP04731.1 - 6.5e-12 45.4 33.7 0.0035 17.7 1.1 6.2 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFP04731.1 - 1.4e-06 28.1 40.8 0.23 11.5 0.3 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger DUF3268 PF11672.8 KFP04731.1 - 2.2e-05 24.7 10.1 0.091 13.1 0.1 3.1 3 0 0 3 3 3 2 zinc-finger-containing domain C1_1 PF00130.22 KFP04731.1 - 2.3e-05 24.2 20.4 0.055 13.4 0.9 4.9 2 2 3 5 5 5 2 Phorbol esters/diacylglycerol binding domain (C1 domain) XPA_N PF01286.18 KFP04731.1 - 2.7e-05 24.1 15.7 1.1 9.4 0.3 6.1 6 0 0 6 6 6 1 XPA protein N-terminal Zn-ribbon_8 PF09723.10 KFP04731.1 - 4.7e-05 23.4 19.1 0.024 14.8 1.6 4.8 3 3 2 5 5 5 2 Zinc ribbon domain zf-Di19 PF05605.12 KFP04731.1 - 5.8e-05 23.3 27.2 0.11 12.8 1.1 4.4 2 1 3 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 KFP04731.1 - 6.5e-05 22.4 16.3 1.6 8.4 0.0 6.0 6 0 0 6 6 6 2 Ubiquitin-Binding Zinc Finger Prok-RING_1 PF14446.6 KFP04731.1 - 9.9e-05 22.2 13.5 12 6.0 0.0 6.1 5 1 0 5 5 5 0 Prokaryotic RING finger family 1 PHF5 PF03660.14 KFP04731.1 - 0.00094 19.4 7.8 0.68 10.2 0.2 3.1 1 1 2 3 3 3 1 PHF5-like protein Zf_RING PF16744.5 KFP04731.1 - 0.001 19.1 15.5 1.9 8.7 0.1 5.6 1 1 4 5 5 5 1 KIAA1045 RING finger BolA PF01722.18 KFP04731.1 - 0.0023 18.2 4.7 1.4 9.2 0.1 3.3 1 1 2 3 3 3 1 BolA-like protein zf-trcl PF13451.6 KFP04731.1 - 0.0054 16.6 16.1 0.59 10.1 0.1 5.8 6 0 0 6 6 6 1 Probable zinc-ribbon domain FYDLN_acid PF09538.10 KFP04731.1 - 0.0072 17.0 9.4 1.4 9.7 0.2 4.8 1 1 3 4 4 4 1 Protein of unknown function (FYDLN_acid) zf-AN1 PF01428.16 KFP04731.1 - 0.01 16.0 26.4 2.9 8.1 0.2 6.2 5 1 1 6 6 6 1 AN1-like Zinc finger C1_2 PF03107.16 KFP04731.1 - 0.011 16.0 26.0 9.5 6.6 3.2 5.9 1 1 4 5 5 5 0 C1 domain LIM PF00412.22 KFP04731.1 - 0.013 15.7 19.3 0.29 11.4 1.8 5.1 1 1 4 5 5 5 0 LIM domain zinc-ribbons_6 PF07191.12 KFP04731.1 - 0.053 13.5 19.8 8.4 6.5 0.2 5.3 2 2 1 4 4 4 0 zinc-ribbons Zn_ribbon_SprT PF17283.2 KFP04731.1 - 0.071 13.0 20.3 0.2 11.6 0.4 4.5 3 2 1 4 4 4 0 SprT-like zinc ribbon domain zf-C2HC_2 PF13913.6 KFP04731.1 - 0.076 12.9 0.1 0.076 12.9 0.1 6.7 6 2 0 6 6 6 0 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 KFP04731.1 - 0.09 13.5 12.2 1.4 9.7 0.8 3.4 1 1 2 3 3 3 0 zinc-ribbon family HypA PF01155.19 KFP04731.1 - 0.14 12.2 13.0 0.58 10.2 0.9 3.4 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_C2H2_ZHX PF18387.1 KFP04731.1 - 0.15 11.7 0.3 0.15 11.7 0.3 4.6 1 1 5 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF2225 PF09986.9 KFP04731.1 - 0.17 11.6 13.1 0.98 9.1 0.3 4.4 3 2 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF2256 PF10013.9 KFP04731.1 - 0.21 11.8 18.2 9.5 6.4 0.0 6.0 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) CpXC PF14353.6 KFP04731.1 - 0.22 11.5 15.4 3.1 7.9 0.2 5.1 2 2 2 5 5 5 0 CpXC protein FYVE PF01363.21 KFP04731.1 - 0.23 11.6 22.5 12 6.1 13.1 4.0 1 1 1 2 2 2 0 FYVE zinc finger Scramblase PF03803.15 KFP04731.1 - 0.29 10.4 1.1 3.9 6.7 0.1 2.1 1 1 0 2 2 2 0 Scramblase PyrI_C PF02748.15 KFP04731.1 - 0.4 10.6 15.6 6.2 6.8 0.3 5.3 3 1 3 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF2180 PF09947.9 KFP04731.1 - 0.54 10.3 13.1 2.5 8.2 0.3 3.9 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) PHD PF00628.29 KFP04731.1 - 0.62 10.0 14.7 13 5.8 5.4 4.6 3 1 1 4 4 4 0 PHD-finger Ribosomal_L28 PF00830.19 KFP04731.1 - 0.72 10.1 15.8 1 9.6 0.3 4.9 6 0 0 6 6 5 0 Ribosomal L28 family zinc_ribbon_9 PF14369.6 KFP04731.1 - 0.76 10.1 0.1 0.76 10.1 0.1 5.1 6 0 0 6 6 5 0 zinc-ribbon zf-nanos PF05741.13 KFP04731.1 - 0.81 10.0 20.1 6.3 7.1 0.3 5.9 5 1 0 5 5 5 0 Nanos RNA binding domain Baculo_IE-1 PF05290.11 KFP04731.1 - 1.3 9.0 11.8 14 5.6 0.4 4.7 2 2 3 5 5 5 0 Baculovirus immediate-early protein (IE-0) Chordopox_RPO7 PF05864.12 KFP04731.1 - 1.6 9.1 7.0 4.9 7.5 0.0 4.0 5 1 0 5 5 4 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) zf-HIT PF04438.16 KFP04731.1 - 1.6 8.7 26.1 1.2 9.1 0.6 5.8 6 0 0 6 6 6 0 HIT zinc finger zf-MYST PF17772.1 KFP04731.1 - 1.7 8.3 14.3 7.7 6.2 1.3 4.9 3 2 3 6 6 6 0 MYST family zinc finger domain DUF530 PF04409.12 KFP04731.1 - 1.9 6.8 4.0 1.8 6.9 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF530) Zn_ribbon_recom PF13408.6 KFP04731.1 - 2.3 8.8 19.6 15 6.2 2.4 4.3 1 1 2 3 3 3 0 Recombinase zinc beta ribbon domain C1_4 PF07975.12 KFP04731.1 - 3.4 8.0 24.6 7.4 6.9 5.3 4.5 1 1 4 5 5 5 0 TFIIH C1-like domain zf-C2H2_9 PF16293.5 KFP04731.1 - 3.6 7.5 0.0 3.6 7.5 0.0 3.3 6 0 0 6 6 3 0 C2H2 type zinc-finger (1 copy) zf-LYAR PF08790.11 KFP04731.1 - 3.7 7.6 15.9 1.4 8.9 0.5 4.9 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger Snf7 PF03357.21 KFP04732.1 - 7.3e-21 74.5 14.8 8.2e-21 74.4 14.8 1.0 1 0 0 1 1 1 1 Snf7 HAP1_N PF04849.13 KFP04732.1 - 0.0037 16.5 4.5 0.0044 16.3 4.5 1.0 1 0 0 1 1 1 1 HAP1 N-terminal conserved region YlqD PF11068.8 KFP04732.1 - 0.087 13.2 6.0 0.16 12.4 6.0 1.5 1 1 0 1 1 1 0 YlqD protein Cytochrom_B562 PF07361.11 KFP04732.1 - 1 10.1 9.6 0.2 12.3 1.3 2.8 1 1 1 2 2 2 0 Cytochrome b562 Spc24 PF08286.11 KFP04732.1 - 1.9 8.7 5.5 2.7 8.3 4.7 1.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 SH3_9 PF14604.6 KFP04733.1 - 1e-15 57.3 0.2 1.7e-15 56.6 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain PID PF00640.23 KFP04733.1 - 2.8e-09 37.1 0.0 9.4e-09 35.4 0.0 1.7 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) SH3_1 PF00018.28 KFP04733.1 - 5.3e-08 32.4 0.0 9.2e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP04733.1 - 0.00067 19.3 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain FERM_f0 PF16511.5 KFP04734.1 - 0.00023 21.4 0.0 0.0011 19.3 0.0 1.9 2 0 0 2 2 2 1 N-terminal or F0 domain of Talin-head FERM Thioredoxin_8 PF13905.6 KFP04735.1 - 2.9e-24 85.2 0.0 4.6e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KFP04735.1 - 9.4e-05 22.8 0.0 0.00016 22.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 KFP04735.1 - 0.00059 19.7 0.0 0.037 13.8 0.0 2.3 2 0 0 2 2 2 1 F plasmid transfer operon protein Redoxin PF08534.10 KFP04735.1 - 0.0013 18.5 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 KFP04735.1 - 0.014 15.4 0.0 0.073 13.1 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin Urotensin_II PF02083.15 KFP04735.1 - 0.15 11.8 1.0 0.31 10.8 1.0 1.5 1 0 0 1 1 1 0 Urotensin II AhpC-TSA PF00578.21 KFP04735.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.6 1 1 0 1 1 1 0 AhpC/TSA family AMP-binding PF00501.28 KFP04736.1 - 1.1e-69 235.1 0.0 1.4e-69 234.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFP04736.1 - 1.4e-05 26.0 0.0 3.3e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TRAPP PF04051.16 KFP04737.1 - 3.1e-29 101.6 0.0 4e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component La PF05383.17 KFP04739.1 - 3.2e-18 65.5 0.2 6.3e-18 64.6 0.2 1.5 1 0 0 1 1 1 1 La domain AMP-binding PF00501.28 KFP04740.1 - 1.5e-83 280.8 0.3 1.3e-58 198.7 0.0 2.4 2 1 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.11 KFP04740.1 - 9e-25 87.7 0.3 1.8e-24 86.7 0.3 1.6 1 0 0 1 1 1 1 DMAP1-binding Domain zf-C2H2 PF00096.26 KFP04742.1 - 2.4e-21 74.9 23.2 1.8e-05 24.9 0.5 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP04742.1 - 1.2e-16 60.3 35.3 8.8e-08 32.2 1.4 5.6 5 1 1 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP04742.1 - 8.2e-11 41.8 21.6 0.00026 21.5 0.3 4.7 4 1 0 4 4 4 4 C2H2-type zinc finger FOXP-CC PF16159.5 KFP04742.1 - 6.6e-06 26.7 15.8 0.0013 19.3 0.1 4.5 1 1 4 5 5 5 2 FOXP coiled-coil domain PcF PF09461.10 KFP04742.1 - 0.0019 18.5 5.2 2.4 8.6 0.4 3.2 2 1 1 3 3 3 2 Phytotoxin PcF protein zf-met PF12874.7 KFP04742.1 - 0.0026 18.1 6.0 1.7 9.2 0.2 4.2 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFP04742.1 - 0.004 17.4 7.6 0.086 13.1 0.7 3.0 1 1 2 3 3 3 2 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KFP04742.1 - 0.0041 17.3 13.0 0.42 10.8 2.7 3.6 2 1 1 3 3 3 2 Aberrant zinc-finger CHORD PF04968.12 KFP04742.1 - 0.052 14.3 16.7 3.3 8.5 0.3 3.9 2 1 2 4 4 4 0 CHORD zf-H2C2_5 PF13909.6 KFP04742.1 - 0.061 13.1 15.4 0.16 11.8 0.0 4.8 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFP04742.1 - 0.19 12.1 16.0 1.2 9.5 0.2 4.9 4 2 0 4 4 4 0 Zinc-finger double-stranded RNA-binding DUF629 PF04780.12 KFP04742.1 - 3.8 5.9 7.0 8.4 4.8 4.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF629) SUZ PF12752.7 KFP04743.1 - 6e-12 46.1 4.4 6e-12 46.1 4.4 4.5 5 0 0 5 5 5 1 SUZ domain R3H PF01424.22 KFP04743.1 - 9.5e-11 41.5 0.1 2.8e-10 40.0 0.1 1.9 1 0 0 1 1 1 1 R3H domain STAC2_u1 PF16664.5 KFP04744.1 - 1.1e-06 29.1 0.0 1.5e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Unstructured on SH3 and cysteine-rich domain-containing protein 2 C1_1 PF00130.22 KFP04744.1 - 0.0019 18.0 5.8 0.0071 16.2 6.3 1.7 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.11 KFP04744.1 - 0.043 14.1 5.2 0.093 13.0 5.2 1.6 1 0 0 1 1 1 0 RING-like domain SHMT PF00464.19 KFP04745.1 - 5.2e-209 693.8 0.0 6e-209 693.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Coat_F PF07875.12 KFP04745.1 - 0.48 10.7 2.2 0.37 11.1 0.2 1.8 2 0 0 2 2 2 0 Coat F domain STAT_bind PF02864.15 KFP04746.1 - 3.7e-41 140.8 1.5 7.5e-41 139.8 1.5 1.5 1 0 0 1 1 1 1 STAT protein, DNA binding domain SH2 PF00017.24 KFP04746.1 - 9.4e-10 38.5 0.0 2.2e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 SH2 domain NEMP PF10225.9 KFP04747.1 - 0.027 14.2 0.6 0.036 13.7 0.6 1.1 1 0 0 1 1 1 0 NEMP family NEMP PF10225.9 KFP04748.1 - 4.5e-23 82.2 0.0 5.9e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 NEMP family BTB PF00651.31 KFP04749.1 - 1.3e-23 83.3 0.1 2.6e-23 82.3 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFP04749.1 - 1.4e-15 56.9 44.2 2.9e-07 30.6 5.2 9.3 10 0 0 10 10 10 5 Zinc-finger double domain zf-C2H2_3rep PF18868.1 KFP04749.1 - 1e-05 26.2 3.9 1e-05 26.2 3.9 4.1 2 2 1 4 4 4 3 Zinc finger C2H2-type, 3 repeats zf-C2H2 PF00096.26 KFP04749.1 - 3.8e-05 23.9 82.1 0.0027 18.1 3.6 9.7 10 0 0 10 10 10 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP04749.1 - 5.2e-05 23.7 79.2 0.19 12.6 2.9 10.4 10 0 0 10 10 10 7 C2H2-type zinc finger BolA PF01722.18 KFP04749.1 - 0.087 13.1 5.2 8.7 6.7 0.1 3.8 3 1 1 4 4 4 0 BolA-like protein zinc_ribbon_15 PF17032.5 KFP04749.1 - 0.86 10.4 24.2 8.7 7.2 0.7 5.5 1 1 5 6 6 6 0 zinc-ribbon family DNA_primase_S PF01896.19 KFP04750.1 - 3.3e-26 92.4 0.0 2.6e-25 89.5 0.0 2.1 1 1 0 1 1 1 1 DNA primase small subunit NAC PF01849.18 KFP04751.1 - 2.4e-25 88.3 1.0 9.9e-25 86.3 0.2 2.2 2 0 0 2 2 2 1 NAC domain RNA_pol_Rpo13 PF12136.8 KFP04751.1 - 0.043 13.7 3.9 0.097 12.6 3.9 1.6 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain CS PF04969.16 KFP04752.1 - 5e-08 33.9 0.2 7e-08 33.4 0.2 1.2 1 0 0 1 1 1 1 CS domain Pkinase_C PF00433.24 KFP04752.1 - 0.38 11.5 7.2 1.2 9.9 7.2 1.9 2 0 0 2 2 2 0 Protein kinase C terminal domain ATP-synt_ab PF00006.25 KFP04753.1 - 2e-27 96.2 0.0 2.9e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KFP04753.1 - 1.5e-06 28.6 0.4 3.5e-06 27.4 0.4 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 KFP04753.1 - 0.0064 15.7 0.1 0.0077 15.4 0.1 1.1 1 0 0 1 1 1 1 NB-ARC domain RsgA_GTPase PF03193.16 KFP04753.1 - 0.0073 16.2 0.0 0.0095 15.9 0.0 1.1 1 0 0 1 1 1 1 RsgA GTPase ATPase PF06745.13 KFP04753.1 - 0.0077 15.6 0.1 0.011 15.2 0.1 1.2 1 0 0 1 1 1 1 KaiC ATPase_2 PF01637.18 KFP04753.1 - 0.028 14.3 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KFP04753.1 - 0.033 13.9 0.1 0.18 11.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KFP04753.1 - 0.046 14.0 0.3 0.08 13.3 0.3 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFP04753.1 - 0.05 14.1 0.1 0.078 13.5 0.1 1.3 1 0 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 KFP04753.1 - 0.088 12.0 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 KFP04753.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 KFP04753.1 - 0.14 12.6 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 KFP04753.1 - 0.15 12.4 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KFP04753.1 - 0.2 11.1 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 KFP04753.1 - 0.2 10.5 0.1 0.28 10.0 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ATP-synt_ab PF00006.25 KFP04754.1 - 7.7e-23 81.3 0.2 1e-22 80.9 0.2 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain T3SS_ATPase_C PF18269.1 KFP04754.1 - 0.0052 16.6 0.2 0.077 12.9 0.2 2.3 1 1 0 1 1 1 1 T3SS EscN ATPase C-terminal domain MIP PF00230.20 KFP04755.1 - 5.1e-54 183.4 1.6 5.8e-54 183.2 1.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein TIMELESS PF04821.14 KFP04756.1 - 5.8e-80 268.5 0.1 8.1e-80 268.0 0.1 1.2 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 KFP04756.1 - 7.4e-35 121.1 0.0 1.2e-34 120.5 0.0 1.3 1 0 0 1 1 1 1 Timeless protein C terminal region UCH_1 PF13423.6 KFP04757.1 - 2.3e-104 349.4 0.1 3.2e-104 349.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 KFP04757.1 - 1.1e-07 31.6 0.6 2.1e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase WD40_like PF17005.5 KFP04757.1 - 4e-05 23.1 0.1 6.8e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 WD40-like domain Citrate_synt PF00285.21 KFP04758.1 - 8.1e-103 344.3 0.0 9.4e-103 344.0 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Queuosine_synth PF02547.15 KFP04758.1 - 0.0093 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein PAS_3 PF08447.12 KFP04758.1 - 0.089 13.1 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 PAS fold Polyketide_cyc PF03364.20 KFP04759.1 - 3.3e-26 92.0 0.1 3.9e-26 91.8 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KFP04759.1 - 0.00012 22.3 0.0 0.00016 22.0 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Ank_2 PF12796.7 KFP04760.1 - 4.1e-160 520.8 71.8 3.3e-19 69.3 0.1 13.8 2 2 13 15 15 15 15 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP04760.1 - 2.7e-144 467.9 42.8 9.8e-11 42.0 0.2 19.9 10 4 11 21 21 21 20 Ankyrin repeats (many copies) Ank PF00023.30 KFP04760.1 - 2.2e-122 394.7 72.3 1.4e-06 28.4 0.2 26.7 26 1 0 26 26 26 26 Ankyrin repeat Ank_3 PF13606.6 KFP04760.1 - 8.4e-112 351.4 53.3 0.00022 21.4 0.0 28.0 27 1 0 27 27 27 25 Ankyrin repeat Ank_5 PF13857.6 KFP04760.1 - 3.5e-107 349.1 57.3 5.4e-10 39.3 0.1 21.8 6 5 16 23 23 23 21 Ankyrin repeats (many copies) GATase_7 PF13537.6 KFP04760.1 - 0.00073 19.4 0.1 29 4.6 0.0 6.3 6 1 0 6 6 6 0 Glutamine amidotransferase domain PEGA PF08308.11 KFP04760.1 - 0.0098 15.8 0.0 25 4.9 0.0 5.2 4 0 0 4 4 4 1 PEGA domain USP8_interact PF08941.10 KFP04761.1 - 2.1e-14 53.7 4.4 3.6e-14 53.0 4.4 1.4 1 0 0 1 1 1 1 USP8 interacting zf-rbx1 PF12678.7 KFP04761.1 - 4.2e-06 27.0 5.4 4.2e-06 27.0 5.4 2.6 2 1 1 3 3 3 1 RING-H2 zinc finger domain Sina PF03145.16 KFP04761.1 - 4.6e-06 26.7 2.4 6.3e-06 26.3 2.4 1.2 1 0 0 1 1 1 1 Seven in absentia protein family zf-C3HC4 PF00097.25 KFP04761.1 - 2.6e-05 24.0 3.7 2.6e-05 24.0 3.7 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP04761.1 - 2.7e-05 24.4 4.6 2.7e-05 24.4 4.6 2.4 3 1 1 4 4 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP04761.1 - 0.00012 21.8 5.6 0.00012 21.8 5.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 KFP04761.1 - 0.00023 21.8 3.5 0.046 14.4 1.8 2.7 1 1 1 2 2 2 1 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 KFP04761.1 - 0.00027 20.8 1.4 0.00027 20.8 1.4 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Trimer_CC PF08954.11 KFP04761.1 - 0.00084 18.9 0.4 0.0037 16.8 0.2 2.1 2 0 0 2 2 2 1 Trimerisation motif zf-RING_5 PF14634.6 KFP04761.1 - 0.0013 18.7 3.6 0.0013 18.7 3.6 2.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KFP04761.1 - 0.0063 16.5 2.2 0.016 15.2 2.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KFP04761.1 - 0.017 15.0 2.1 0.017 15.0 2.1 1.8 2 0 0 2 2 1 0 Prokaryotic RING finger family 4 BLOC1_2 PF10046.9 KFP04761.1 - 0.019 15.3 3.1 0.038 14.3 3.1 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-RING_UBOX PF13445.6 KFP04761.1 - 0.021 14.9 4.7 0.021 14.9 4.7 2.2 3 0 0 3 3 3 0 RING-type zinc-finger zf-RING_6 PF14835.6 KFP04761.1 - 0.023 14.5 0.1 0.023 14.5 0.1 2.2 2 1 0 2 2 2 0 zf-RING of BARD1-type protein DUF641 PF04859.12 KFP04761.1 - 0.024 14.9 0.9 0.042 14.2 0.9 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Atx10homo_assoc PF09759.9 KFP04761.1 - 0.037 14.0 1.7 0.61 10.1 0.4 2.2 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain zf-C3HC4_4 PF15227.6 KFP04761.1 - 0.047 13.8 3.4 0.047 13.8 3.4 2.4 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-CCCH_6 PF18585.1 KFP04761.1 - 0.081 12.8 2.5 0.17 11.8 0.1 2.6 3 0 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 zf-TRAF_2 PF15965.5 KFP04761.1 - 0.081 13.4 11.6 0.098 13.1 7.8 2.4 1 1 1 2 2 2 0 TRAF-like zinc-finger SlyX PF04102.12 KFP04761.1 - 0.088 13.4 5.5 0.25 12.0 5.4 1.9 1 1 0 1 1 1 0 SlyX DUF1754 PF08555.10 KFP04761.1 - 0.13 13.0 0.5 0.18 12.6 0.5 1.2 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Zn_ribbon_17 PF17120.5 KFP04761.1 - 0.66 9.6 13.3 0.089 12.4 4.0 2.5 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type Swi5 PF07061.11 KFP04761.1 - 1.4 9.1 8.2 0.18 11.9 3.3 1.9 2 0 0 2 2 2 0 Swi5 zinc_ribbon_16 PF17034.5 KFP04761.1 - 1.9 8.7 9.5 2.4 8.4 2.8 2.2 2 0 0 2 2 2 0 Zinc-ribbon like family EF-hand_1 PF00036.32 KFP04762.1 - 0.00022 20.5 1.2 0.062 12.9 0.0 3.6 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.6 KFP04762.1 - 0.0036 17.7 0.0 0.016 15.7 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP04762.1 - 0.0057 16.5 0.1 0.058 13.4 0.0 2.6 3 1 0 3 3 3 1 EF-hand domain Ets PF00178.22 KFP04763.1 - 5.6e-23 81.2 0.2 6.5e-23 81.0 0.2 1.1 1 0 0 1 1 1 1 Ets-domain HSF_DNA-bind PF00447.17 KFP04763.1 - 0.035 14.7 0.0 0.041 14.5 0.0 1.2 1 0 0 1 1 1 0 HSF-type DNA-binding Cadherin PF00028.17 KFP04764.1 - 3.8e-10 40.1 0.0 4.3e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 Cadherin domain zf-H2C2_2 PF13465.6 KFP04766.1 - 3.9e-59 194.6 60.2 8e-10 38.7 0.6 8.3 9 0 0 9 9 8 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFP04766.1 - 1.1e-53 176.8 58.4 3.8e-08 33.3 0.7 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP04766.1 - 4.2e-35 117.4 56.7 3.9e-05 24.1 0.5 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP04766.1 - 9.9e-22 76.7 20.0 0.018 15.3 0.5 8.2 8 0 0 8 8 8 7 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFP04766.1 - 3.6e-17 61.6 25.5 0.09 12.4 0.2 8.2 8 0 0 8 8 8 5 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFP04766.1 - 2.3e-15 56.4 31.4 0.0014 18.7 1.9 6.2 4 2 2 6 6 6 6 Zinc ribbon domain zf-C2H2_11 PF16622.5 KFP04766.1 - 2.8e-12 46.2 33.0 0.00073 19.2 0.5 7.4 8 0 0 8 8 7 3 zinc-finger C2H2-type zf-LYAR PF08790.11 KFP04766.1 - 7.4e-12 45.0 28.2 0.26 11.2 0.1 8.2 8 0 0 8 8 8 3 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 KFP04766.1 - 5.6e-11 42.2 47.6 0.019 15.0 1.6 8.3 8 0 0 8 8 8 5 C2H2-type zinc finger zf-Di19 PF05605.12 KFP04766.1 - 7.1e-11 42.2 29.2 0.00066 19.9 1.1 5.2 3 2 0 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_9 PF14369.6 KFP04766.1 - 1.4e-10 41.3 25.7 0.098 12.9 0.2 7.8 8 0 0 8 8 8 3 zinc-ribbon DZR PF12773.7 KFP04766.1 - 5.9e-10 39.0 23.3 0.0013 18.7 6.0 5.0 1 1 2 3 3 3 3 Double zinc ribbon XPA_N PF01286.18 KFP04766.1 - 3.9e-09 36.4 26.6 0.19 11.8 0.2 8.0 8 0 0 8 8 8 3 XPA protein N-terminal Zn_ribbon_SprT PF17283.2 KFP04766.1 - 8e-08 32.1 35.4 0.11 12.5 3.8 6.8 4 3 4 8 8 8 5 SprT-like zinc ribbon domain zinc_ribbon_15 PF17032.5 KFP04766.1 - 7.8e-07 29.8 21.4 0.16 12.8 4.8 4.6 1 1 3 4 4 4 4 zinc-ribbon family zf-met PF12874.7 KFP04766.1 - 8.4e-07 29.2 40.2 0.43 11.0 1.0 8.1 8 0 0 8 8 8 3 Zinc-finger of C2H2 type zf-trcl PF13451.6 KFP04766.1 - 9.1e-07 28.7 21.5 0.74 9.8 0.2 7.6 8 0 0 8 8 8 1 Probable zinc-ribbon domain FYDLN_acid PF09538.10 KFP04766.1 - 1.2e-06 29.2 14.5 23 5.7 0.1 7.0 3 2 3 6 6 6 0 Protein of unknown function (FYDLN_acid) HypA PF01155.19 KFP04766.1 - 2e-06 27.8 19.7 0.13 12.3 0.1 4.6 1 1 3 4 4 4 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA YhfH PF14149.6 KFP04766.1 - 2e-05 24.4 26.3 3.7 7.6 0.2 7.8 8 0 0 8 8 8 0 YhfH-like protein zf-AN1 PF01428.16 KFP04766.1 - 3.4e-05 23.9 33.4 2.4 8.4 0.2 8.1 7 1 1 8 8 8 1 AN1-like Zinc finger TFIIS_C PF01096.18 KFP04766.1 - 4.3e-05 23.3 29.0 3.4 7.6 0.2 8.0 8 0 0 8 8 8 0 Transcription factor S-II (TFIIS) zf-BED PF02892.15 KFP04766.1 - 7.5e-05 22.7 38.9 0.56 10.3 0.4 7.6 1 1 6 7 7 7 1 BED zinc finger zf-C2H2_8 PF15909.5 KFP04766.1 - 0.00011 22.4 22.6 0.09 13.1 0.6 4.5 1 1 4 5 5 5 2 C2H2-type zinc ribbon zf-HIT PF04438.16 KFP04766.1 - 0.00015 21.6 33.1 0.73 9.8 0.3 7.8 8 0 0 8 8 8 1 HIT zinc finger ADK_lid PF05191.14 KFP04766.1 - 0.00018 21.4 22.2 0.031 14.3 0.8 5.8 5 2 0 5 5 5 2 Adenylate kinase, active site lid DUF3268 PF11672.8 KFP04766.1 - 0.00021 21.6 16.4 0.7 10.2 0.1 4.3 2 1 0 4 4 4 2 zinc-finger-containing domain Zn-C2H2_12 PF18112.1 KFP04766.1 - 0.00093 19.6 12.2 6 7.4 0.0 5.9 6 0 0 6 6 5 0 Autophagy receptor zinc finger-C2H2 domain zinc-ribbons_6 PF07191.12 KFP04766.1 - 0.0019 18.1 24.7 0.53 10.3 0.6 5.6 1 1 2 3 3 3 1 zinc-ribbons CpXC PF14353.6 KFP04766.1 - 0.0021 18.1 26.6 3 7.9 0.1 7.5 1 1 6 8 8 8 1 CpXC protein zf-C2HC_2 PF13913.6 KFP04766.1 - 0.0026 17.6 30.9 0.53 10.2 0.9 7.5 7 1 0 7 7 7 1 zinc-finger of a C2HC-type zf-ribbon_3 PF13248.6 KFP04766.1 - 0.0036 16.7 33.6 0.69 9.4 0.1 7.8 8 0 0 8 8 8 2 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 KFP04766.1 - 0.004 16.6 25.3 2.4 7.8 0.1 7.5 8 0 0 8 8 8 1 TFIIB zinc-binding PRP21_like_P PF12230.8 KFP04766.1 - 0.0043 17.0 0.9 1.2 8.9 0.1 2.4 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Zn_Tnp_IS1595 PF12760.7 KFP04766.1 - 0.0045 16.9 41.3 0.058 13.4 3.0 6.0 2 2 4 7 7 7 3 Transposase zinc-ribbon domain DNA_RNApol_7kD PF03604.13 KFP04766.1 - 0.0062 16.2 24.4 15 5.4 0.1 7.9 8 0 0 8 8 8 0 DNA directed RNA polymerase, 7 kDa subunit zf-RING_7 PF02591.15 KFP04766.1 - 0.0073 16.5 25.6 5.1 7.4 0.2 7.7 8 0 0 8 8 8 0 C4-type zinc ribbon domain C1_4 PF07975.12 KFP04766.1 - 0.0075 16.5 27.7 1.9 8.8 0.7 6.0 1 1 5 7 7 7 2 TFIIH C1-like domain GAGA PF09237.11 KFP04766.1 - 0.012 15.5 23.6 1.5 8.7 1.0 5.3 3 2 2 5 5 5 0 GAGA factor HalOD2 PF18547.1 KFP04766.1 - 0.041 13.8 27.2 0.76 9.7 0.2 6.9 5 1 2 7 7 7 0 Halobacterial output domain 2 zf-C2HE PF16278.5 KFP04766.1 - 0.05 14.1 38.0 0.18 12.2 1.0 7.6 1 1 5 7 7 7 0 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_4 PF13717.6 KFP04766.1 - 0.051 13.5 30.8 1.7 8.6 2.1 7.3 6 2 0 6 6 6 0 zinc-ribbon domain DUF2256 PF10013.9 KFP04766.1 - 0.057 13.5 21.2 67 3.7 0.1 7.8 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) IBR PF01485.21 KFP04766.1 - 0.07 13.4 30.1 0.43 10.8 1.9 4.9 1 1 3 4 4 4 0 IBR domain, a half RING-finger domain TerY_C PF15616.6 KFP04766.1 - 0.085 13.0 16.0 0.36 10.9 1.4 3.6 1 1 1 3 3 3 0 TerY-C metal binding domain LIM PF00412.22 KFP04766.1 - 0.1 12.8 26.8 0.11 12.8 1.1 6.4 1 1 6 7 7 6 0 LIM domain Ogr_Delta PF04606.12 KFP04766.1 - 0.12 12.4 0.2 0.12 12.4 0.2 6.1 5 1 1 6 6 6 0 Ogr/Delta-like zinc finger Zn_ribbon_recom PF13408.6 KFP04766.1 - 0.18 12.3 28.2 1.9 9.0 1.2 6.0 1 1 5 6 6 6 0 Recombinase zinc beta ribbon domain Raffinose_syn PF05691.12 KFP04766.1 - 0.18 9.5 0.4 2.9 5.5 0.0 2.5 1 1 1 2 2 2 0 Raffinose synthase or seed imbibition protein Sip1 zf-C2H2_2 PF12756.7 KFP04766.1 - 2.2 8.7 26.8 4 7.8 0.6 6.2 1 1 4 6 6 6 0 C2H2 type zinc-finger (2 copies) YacG PF03884.14 KFP04766.1 - 2.5 7.9 19.0 16 5.3 0.0 6.2 8 0 0 8 8 7 0 DNA gyrase inhibitor YacG zf_C2H2_ZHX PF18387.1 KFP04766.1 - 4.8 6.9 34.9 1.4 8.6 0.3 7.0 1 1 6 7 7 7 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HC5 PF06221.13 KFP04766.1 - 5.1 7.2 29.2 0.17 11.9 1.8 6.8 4 1 3 7 7 7 0 Putative zinc finger motif, C2HC5-type zf-C2H2_9 PF16293.5 KFP04766.1 - 5.1 7.0 12.6 45 4.0 0.1 5.3 5 1 1 6 6 5 0 C2H2 type zinc-finger (1 copy) Terminase_GpA PF05876.12 KFP04766.1 - 5.2 5.5 23.1 1.8 7.0 3.3 3.9 3 1 1 4 4 4 0 Phage terminase large subunit (GpA) zinc_ribbon_10 PF10058.9 KFP04766.1 - 8.3 6.2 26.5 45 3.9 0.1 7.4 7 1 1 8 8 8 0 Predicted integral membrane zinc-ribbon metal-binding protein TRAF6_Z2 PF18048.1 KFP04766.1 - 9.1 6.5 13.2 44 4.3 1.2 4.8 5 0 0 5 5 4 0 TNF receptor-associated factor 6 zinc finger 2 Cys_rich_CPXG PF14255.6 KFP04766.1 - 10 6.1 19.1 13 5.8 0.1 6.0 7 0 0 7 7 6 0 Cysteine-rich CPXCG Ion_trans PF00520.31 KFP04767.1 - 3.7e-48 163.9 11.9 4.9e-48 163.5 11.9 1.0 1 0 0 1 1 1 1 Ion transport protein 7tm_2 PF00002.24 KFP04768.1 - 1.4e-82 276.7 21.7 1.8e-82 276.3 21.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFP04768.1 - 8.1e-12 45.3 1.5 8.1e-12 45.3 1.5 2.6 4 0 0 4 4 4 1 Hormone receptor domain DUF4418 PF14387.6 KFP04768.1 - 0.7 10.1 9.3 0.12 12.6 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) Acyltransferase PF01553.21 KFP04769.1 - 6e-32 110.1 0.2 1.1e-31 109.3 0.0 1.5 2 0 0 2 2 2 1 Acyltransferase UBA2_C PF16195.5 KFP04770.1 - 0.33 11.7 12.1 0.1 13.3 3.9 2.2 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus MIase PF02426.16 KFP04770.1 - 6.1 7.1 7.0 0.94 9.7 0.9 2.2 2 0 0 2 2 2 0 Muconolactone delta-isomerase AAA_lid_3 PF17862.1 KFP04771.1 - 1.5e-12 47.1 0.0 3.2e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KFP04771.1 - 2.5e-07 30.5 0.5 4.8e-07 29.6 0.5 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain RILP PF11461.8 KFP04771.1 - 0.018 15.2 3.5 0.037 14.3 3.5 1.5 1 0 0 1 1 1 0 Rab interacting lysosomal protein HR1 PF02185.16 KFP04771.1 - 0.31 11.2 5.6 0.7 10.0 5.6 1.6 1 0 0 1 1 1 0 Hr1 repeat SWIB PF02201.18 KFP04772.1 - 8.9e-21 73.6 0.1 2.2e-20 72.3 0.1 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain RVT_1 PF00078.27 KFP04773.1 - 0.053 13.0 0.0 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) 7tm_1 PF00001.21 KFP04775.1 - 1.1e-65 221.6 24.5 1.3e-65 221.3 24.5 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP04775.1 - 2.6e-15 56.5 21.0 3e-15 56.3 21.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP04775.1 - 1.3e-10 41.3 20.3 2.8e-10 40.3 20.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFP04775.1 - 2.8e-08 33.5 20.0 4.1e-08 32.9 20.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv TctB PF07331.11 KFP04775.1 - 0.0016 18.7 7.6 0.0016 18.7 7.6 2.5 2 1 1 3 3 3 1 Tripartite tricarboxylate transporter TctB family C1q PF00386.21 KFP04776.1 - 9.9e-35 119.5 1.2 1.2e-34 119.2 1.2 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFP04776.1 - 2.8e-08 33.4 13.2 4.4e-08 32.8 13.2 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Ion_trans PF00520.31 KFP04777.1 - 1.2e-243 804.1 77.9 3.9e-74 249.0 17.5 4.2 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 KFP04777.1 - 3.4e-12 45.8 80.3 1.8e-05 23.6 0.6 9.6 6 3 3 9 9 9 6 Polycystin cation channel UPF0542 PF15086.6 KFP04777.1 - 0.05 13.5 13.2 2.8 7.9 0.1 4.5 4 0 0 4 4 4 0 Uncharacterised protein family UPF0542 Shisa PF13908.6 KFP04777.1 - 0.077 13.2 0.1 44 4.2 0.0 4.4 4 1 0 4 4 4 0 Wnt and FGF inhibitory regulator MscL PF01741.18 KFP04777.1 - 0.079 13.3 3.7 16 5.9 0.0 4.1 4 0 0 4 4 4 0 Large-conductance mechanosensitive channel, MscL TMEM208_SND2 PF05620.11 KFP04777.1 - 0.66 9.7 4.5 2.5 7.8 0.0 3.6 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 NicO PF03824.16 KFP04777.1 - 8.8 5.6 15.0 22 4.3 0.0 3.7 2 1 0 2 2 2 0 High-affinity nickel-transport protein SieB PF14163.6 KFP04777.1 - 9.5 5.7 17.3 0.95 8.9 0.0 4.9 5 0 0 5 5 5 0 Super-infection exclusion protein B B9-C2 PF07162.11 KFP04778.1 - 4.9e-48 163.5 0.1 5.6e-48 163.3 0.1 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein DUF1143 PF06608.11 KFP04778.1 - 0.087 12.9 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1143) ENTH PF01417.20 KFP04779.1 - 9.3e-54 180.8 0.2 2.2e-53 179.6 0.2 1.7 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KFP04779.1 - 3.6e-06 26.2 0.1 5.3e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 KFP04779.1 - 7.7e-05 22.6 0.9 0.00014 21.7 0.3 1.7 2 0 0 2 2 2 1 VHS domain UIM PF02809.20 KFP04779.1 - 1.6 8.8 14.3 0.21 11.6 5.1 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif Pribosyl_synth PF14572.6 KFP04780.1 - 1.8e-100 334.5 1.4 2.8e-100 333.9 1.4 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KFP04780.1 - 3.6e-40 136.5 0.5 7.9e-40 135.4 0.5 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KFP04780.1 - 2.5e-08 33.6 0.1 3e-06 26.8 0.1 2.2 2 0 0 2 2 2 2 Phosphoribosyl transferase domain UN_NPL4 PF11543.8 KFP04780.1 - 0.041 14.4 0.0 0.077 13.5 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 RelB PF04221.12 KFP04780.1 - 0.045 13.7 0.2 5.4 7.0 0.0 2.6 2 0 0 2 2 2 0 RelB antitoxin 7tm_1 PF00001.21 KFP04781.1 - 2.3e-43 148.4 20.7 3.2e-43 147.9 20.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Cyt_bd_oxida_II PF02322.15 KFP04781.1 - 0.00012 21.5 18.3 0.00022 20.7 17.7 1.5 1 1 1 2 2 2 1 Cytochrome bd terminal oxidase subunit II 7TM_GPCR_Srx PF10328.9 KFP04781.1 - 0.002 17.8 13.1 0.002 17.8 13.1 2.4 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Folliculin PF11704.8 KFP04782.1 - 2.7e-08 33.9 0.1 5.6e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Topoisom_bac PF01131.20 KFP04783.1 - 1.5e-116 389.8 0.0 4.6e-116 388.2 0.0 1.7 2 0 0 2 2 2 1 DNA topoisomerase zf-GRF PF06839.12 KFP04783.1 - 1e-36 124.7 20.7 7.6e-20 70.7 5.5 3.3 3 0 0 3 3 3 2 GRF zinc finger Toprim PF01751.22 KFP04783.1 - 3.2e-17 62.6 0.0 1.3e-16 60.6 0.0 2.0 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 KFP04783.1 - 4.5e-12 45.5 1.7 4.5e-12 45.5 1.7 3.6 4 0 0 4 4 4 1 Topoisomerase DNA binding C4 zinc finger zf-C2H2_10 PF16588.5 KFP04783.1 - 0.0036 17.0 1.7 0.01 15.5 1.7 1.7 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC PF00098.23 KFP04783.1 - 0.084 13.0 5.6 0.11 12.7 3.5 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 KFP04783.1 - 0.61 10.0 5.8 2.5 8.0 5.8 2.2 1 0 0 1 1 1 0 Zinc knuckle Gelsolin PF00626.22 KFP04784.1 - 3.5e-62 206.3 2.2 2.8e-15 56.0 0.0 6.7 6 0 0 6 6 6 6 Gelsolin repeat LRR_8 PF13855.6 KFP04784.1 - 1.7e-38 130.1 44.8 1.4e-09 37.5 10.5 6.5 5 1 1 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFP04784.1 - 8.6e-21 73.7 60.4 2.8e-07 30.7 4.2 8.3 2 1 10 12 12 12 12 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP04784.1 - 0.00097 18.7 21.3 0.069 12.7 4.3 4.2 1 1 3 4 4 4 3 Leucine-rich repeat SRP-alpha_N PF04086.13 KFP04784.1 - 0.007 16.3 0.8 0.007 16.3 0.8 1.8 2 0 0 2 2 2 1 Signal recognition particle, alpha subunit, N-terminal LRR_1 PF00560.33 KFP04784.1 - 0.0071 16.7 51.0 2.4 9.1 0.4 11.7 12 1 0 12 12 12 3 Leucine Rich Repeat 2OG-FeII_Oxy_2 PF13532.6 KFP04785.1 - 2.5e-09 37.6 0.0 4.3e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ApoO PF09769.9 KFP04785.1 - 0.078 12.9 0.2 0.14 12.1 0.2 1.3 1 0 0 1 1 1 0 Apolipoprotein O MMR_HSR1_Xtn PF16897.5 KFP04786.1 - 5.8e-43 145.2 0.0 1.1e-42 144.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KFP04786.1 - 4.9e-24 84.1 0.0 8.9e-24 83.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KFP04786.1 - 9.4e-20 70.8 0.0 1.7e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFP04786.1 - 6.2e-10 38.8 0.0 1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KFP04786.1 - 0.023 14.8 0.3 1.5 8.8 0.0 2.3 1 1 1 2 2 2 0 Dynamin family Vac_ImportDeg PF09783.9 KFP04787.1 - 7.9e-55 185.1 5.0 8.9e-55 184.9 5.0 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein ATP12 PF07542.11 KFP04788.1 - 1.3e-37 128.8 0.1 1.9e-37 128.2 0.1 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein VHS PF00790.19 KFP04789.1 - 7.4e-45 152.3 0.2 2.2e-44 150.7 0.0 1.8 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 KFP04789.1 - 1e-27 96.2 2.4 2.4e-27 95.0 2.4 1.7 1 0 0 1 1 1 1 GAT domain ENTH PF01417.20 KFP04789.1 - 0.0095 16.0 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 ENTH domain HEAT_2 PF13646.6 KFP04789.1 - 0.04 14.3 0.1 11 6.5 0.0 2.6 2 0 0 2 2 2 0 HEAT repeats Pap_E4 PF02711.14 KFP04789.1 - 0.23 12.4 1.5 0.36 11.8 0.5 1.8 2 0 0 2 2 2 0 E4 protein HLH PF00010.26 KFP04790.1 - 1.1e-18 66.9 1.2 2.6e-18 65.7 1.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PRKG1_interact PF15898.5 KFP04790.1 - 2.3 9.2 6.7 0.14 13.1 0.8 1.9 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain zf-HC5HC2H PF13771.6 KFP04791.1 - 1.8e-10 40.9 9.5 1.8e-10 40.9 9.5 3.0 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFP04791.1 - 1.4e-09 38.1 8.6 1.4e-09 38.1 8.6 2.3 2 1 0 2 2 2 1 PHD-zinc-finger like domain PEMT PF04191.13 KFP04792.1 - 7.6e-32 109.9 4.5 7.6e-32 109.9 4.5 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase Ras PF00071.22 KFP04793.1 - 3.8e-37 127.4 0.0 5.5e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP04793.1 - 7.3e-13 48.8 0.0 1.1e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP04793.1 - 4e-07 29.6 0.0 7.7e-07 28.7 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP04793.1 - 0.00032 20.3 0.0 0.0034 17.0 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFP04793.1 - 0.009 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 KFP04793.1 - 0.046 13.1 0.0 0.16 11.3 0.0 1.9 2 1 0 2 2 2 0 Bacterial TniB protein GAPT PF11770.8 KFP04793.1 - 0.089 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) MMR_HSR1 PF01926.23 KFP04793.1 - 0.09 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Med9 PF07544.13 KFP04794.1 - 2.8e-20 72.2 5.1 3.1e-20 72.1 5.1 1.0 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.8 KFP04794.1 - 5.3e-08 33.2 3.0 6.1e-08 33.0 3.0 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex APG17 PF04108.12 KFP04794.1 - 0.0019 17.4 0.5 0.0021 17.3 0.5 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 DASH_Duo1 PF08651.10 KFP04794.1 - 0.0088 15.8 0.5 0.012 15.3 0.5 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 HSBP1 PF06825.12 KFP04794.1 - 0.015 15.2 0.7 0.015 15.2 0.7 1.8 2 0 0 2 2 2 0 Heat shock factor binding protein 1 4HB_MCP_1 PF12729.7 KFP04794.1 - 0.015 14.8 0.3 0.017 14.7 0.3 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction COG6 PF06419.11 KFP04794.1 - 0.023 12.9 3.0 0.025 12.8 3.0 1.0 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 ELK PF03789.13 KFP04794.1 - 0.027 14.6 1.8 0.13 12.4 0.5 2.3 2 0 0 2 2 2 0 ELK domain Mrpl_C PF18502.1 KFP04794.1 - 0.032 14.5 1.1 0.037 14.3 1.1 1.1 1 0 0 1 1 1 0 54S ribosomal protein L8 C-terminal domain RPW8 PF05659.11 KFP04794.1 - 0.034 13.8 1.3 0.035 13.8 1.3 1.0 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF3452 PF11934.8 KFP04794.1 - 0.037 13.6 0.9 0.047 13.3 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Enkurin PF13864.6 KFP04794.1 - 0.063 13.7 4.8 0.17 12.3 0.8 2.0 1 1 1 2 2 2 0 Calmodulin-binding FapA PF03961.13 KFP04794.1 - 0.073 11.7 3.1 0.084 11.5 3.1 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A XPC-binding PF09280.11 KFP04794.1 - 0.074 12.8 7.1 4.5 7.1 3.9 2.5 2 1 0 2 2 2 0 XPC-binding domain DUF932 PF06067.11 KFP04794.1 - 0.078 12.7 0.4 0.081 12.7 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF932) DUF2232 PF09991.9 KFP04794.1 - 0.26 10.4 1.1 0.3 10.2 1.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) KIP1 PF07765.12 KFP04794.1 - 0.37 10.9 2.7 0.69 10.1 2.7 1.5 1 1 0 1 1 1 0 KIP1-like protein NT5C PF06941.12 KFP04795.1 - 5.3e-27 94.8 0.0 6e-27 94.7 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) PCI PF01399.27 KFP04796.1 - 1.3e-19 70.7 1.0 5.1e-19 68.7 0.2 2.3 2 0 0 2 2 2 1 PCI domain RasGEF PF00617.19 KFP04796.1 - 0.0052 17.0 0.9 0.49 10.6 0.1 2.9 3 0 0 3 3 3 1 RasGEF domain TPR_1 PF00515.28 KFP04796.1 - 0.0077 16.0 2.5 0.017 15.0 0.9 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFP04796.1 - 0.045 14.0 2.1 1.4 9.3 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat MAS20 PF02064.15 KFP04796.1 - 0.05 13.7 0.2 0.31 11.1 0.1 2.2 2 0 0 2 2 2 0 MAS20 protein import receptor Sel1 PF08238.12 KFP04796.1 - 0.066 13.9 1.0 0.17 12.6 1.0 1.8 1 0 0 1 1 1 0 Sel1 repeat TPR_10 PF13374.6 KFP04796.1 - 0.067 13.1 0.3 1.1 9.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFP04796.1 - 0.073 13.2 2.3 0.16 12.2 0.9 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFP04796.1 - 0.11 12.9 0.1 2.5 8.4 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Folliculin_C PF16692.5 KFP04797.1 - 8.3e-91 303.7 0.1 1.5e-90 302.9 0.1 1.4 1 0 0 1 1 1 1 Folliculin C-terminal domain Folliculin PF11704.8 KFP04797.1 - 1.3e-51 175.2 0.0 2.2e-51 174.4 0.0 1.4 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport DUF5357 PF17310.2 KFP04797.1 - 0.03 12.9 0.0 0.048 12.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5357) PH PF00169.29 KFP04798.1 - 3.3e-19 69.3 0.9 1.8e-16 60.6 0.4 2.6 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KFP04798.1 - 0.0028 18.1 8.7 0.013 15.9 3.3 3.8 3 1 0 3 3 3 1 Pleckstrin homology domain OmpH PF03938.14 KFP04798.1 - 0.0093 16.3 12.7 0.0093 16.3 12.7 4.7 3 1 2 5 5 5 3 Outer membrane protein (OmpH-like) TACI-CRD2 PF09305.10 KFP04799.1 - 2.2e-23 82.0 22.7 1.5e-20 72.9 7.3 3.9 4 0 0 4 4 4 2 TACI, cysteine-rich domain BCMA-Tall_bind PF09257.10 KFP04799.1 - 0.012 15.7 7.0 0.012 15.7 7.0 3.6 4 0 0 4 4 4 0 BCMA, TALL-1 binding UCH PF00443.29 KFP04800.1 - 9.5e-58 195.7 0.1 1.2e-57 195.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP04800.1 - 8.6e-25 88.0 2.8 3.5e-24 86.0 2.8 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFP04800.1 - 6.3e-14 52.0 10.7 6.3e-14 52.0 10.7 2.3 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_C98 PF15499.6 KFP04800.1 - 3.5e-05 23.4 3.3 0.011 15.3 0.1 3.3 3 0 0 3 3 3 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase ISG65-75 PF11727.8 KFP04800.1 - 0.3 10.3 4.6 0.055 12.7 0.7 1.7 2 0 0 2 2 2 0 Invariant surface glycoprotein zf-RING_13 PF17977.1 KFP04800.1 - 0.92 9.7 7.6 4.1 7.6 7.6 2.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain adh_short PF00106.25 KFP04801.1 - 1.5e-52 177.9 0.3 2e-52 177.5 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP04801.1 - 5.2e-37 127.6 0.7 6.6e-37 127.3 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP04801.1 - 2.3e-12 47.2 0.1 3.4e-12 46.7 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFP04801.1 - 2.3e-06 27.2 0.1 3e-05 23.6 0.0 2.6 2 2 0 2 2 2 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 KFP04801.1 - 0.00021 20.5 0.1 0.00029 20.1 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.15 KFP04801.1 - 0.0014 18.9 0.1 0.0031 17.7 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KFP04801.1 - 0.039 14.0 0.2 0.19 11.8 0.2 2.1 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 KFP04801.1 - 0.069 12.5 0.3 0.58 9.5 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HEPN PF05168.14 KFP04801.1 - 0.1 12.7 0.0 0.78 9.9 0.0 2.3 3 0 0 3 3 3 0 HEPN domain Mito_morph_reg PF14972.6 KFP04802.1 - 7.5e-78 259.7 0.7 8.4e-78 259.5 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial morphogenesis regulator Acetyltransf_CG PF14542.6 KFP04803.1 - 1.3e-22 79.7 0.2 1.6e-22 79.4 0.2 1.0 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 KFP04803.1 - 0.0027 17.9 0.0 0.0029 17.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFP04803.1 - 0.017 15.1 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3222 PF11519.8 KFP04803.1 - 0.075 13.3 0.0 0.1 12.9 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3222) Acetyltransf_7 PF13508.7 KFP04803.1 - 0.08 13.4 0.1 0.11 13.0 0.1 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.25 KFP04804.1 - 1.5e-56 191.7 0.0 1.8e-56 191.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP04804.1 - 1.7e-39 135.6 0.0 2.2e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP04804.1 - 1.3e-05 24.6 0.0 2.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFP04804.1 - 0.0016 17.4 0.0 0.0029 16.6 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KFP04804.1 - 0.0034 16.5 0.2 0.0054 15.8 0.2 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 KFP04804.1 - 0.009 14.8 0.1 0.021 13.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFP04804.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFP04804.1 - 0.021 14.4 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF4344 PF14247.6 KFP04804.1 - 0.033 13.9 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase DHR-2 PF06920.13 KFP04804.1 - 0.089 11.4 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Dock homology region 2 RIO1 PF01163.22 KFP04804.1 - 0.098 12.2 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 RIO1 family IRK_C PF17655.1 KFP04806.1 - 1.2e-77 259.5 0.0 1.6e-77 259.1 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFP04806.1 - 9.2e-66 220.0 1.4 1.3e-65 219.5 1.4 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain IRK_N PF08466.10 KFP04806.1 - 2.3e-24 85.3 0.2 4.4e-24 84.4 0.2 1.5 1 0 0 1 1 1 1 Inward rectifier potassium channel N-terminal Ion_trans_2 PF07885.16 KFP04806.1 - 0.038 14.0 5.9 0.096 12.7 5.9 1.7 1 1 0 1 1 1 0 Ion channel WRW PF10206.9 KFP04807.1 - 2.7e-17 63.0 0.0 3.6e-17 62.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f zf-CCCH PF00642.24 KFP04808.1 - 2.5e-18 65.5 33.1 1.8e-07 30.9 0.5 5.5 6 0 0 6 6 6 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFP04808.1 - 1.1e-10 41.2 46.9 6.9e-07 29.1 2.6 7.4 7 1 0 7 7 7 3 Zinc finger domain zf-CCCH_4 PF18044.1 KFP04808.1 - 2.7e-07 30.2 3.8 3.1e-06 26.8 0.3 5.7 7 0 0 7 7 7 2 CCCH-type zinc finger Torus PF16131.5 KFP04808.1 - 2.8e-07 31.2 30.4 0.00024 21.8 1.0 5.4 1 1 4 5 5 5 3 Torus domain zf-CCHC PF00098.23 KFP04808.1 - 2e-06 27.6 3.6 2e-06 27.6 3.6 3.4 4 0 0 4 4 4 1 Zinc knuckle zf-CCCH_3 PF15663.5 KFP04808.1 - 1.3e-05 25.4 10.2 1.3e-05 25.4 10.2 2.9 2 1 1 3 3 3 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 KFP04808.1 - 0.0043 17.5 40.8 0.41 11.2 1.0 7.2 6 2 0 6 6 6 3 RNA-binding, Nab2-type zinc finger zf-CCHC_3 PF13917.6 KFP04808.1 - 0.077 13.0 8.5 0.27 11.2 2.7 3.0 2 0 0 2 2 2 0 Zinc knuckle zf-C3H1 PF10650.9 KFP04808.1 - 0.1 12.4 17.1 0.68 9.7 0.2 4.7 5 0 0 5 5 5 0 Putative zinc-finger domain PPR_2 PF13041.6 KFP04809.1 - 1.3e-47 159.7 0.4 9.6e-15 54.5 0.0 9.0 5 3 4 9 9 9 9 PPR repeat family PPR_3 PF13812.6 KFP04809.1 - 1.4e-35 121.2 0.4 3.2e-07 30.3 0.1 6.4 6 0 0 6 6 6 6 Pentatricopeptide repeat domain PPR PF01535.20 KFP04809.1 - 1.1e-19 69.2 12.4 8.2e-07 28.9 0.1 9.1 10 1 0 10 10 10 4 PPR repeat PPR_long PF17177.4 KFP04809.1 - 1e-18 67.5 0.0 1.9e-12 47.0 0.0 4.4 2 2 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KFP04809.1 - 1.1e-11 44.2 8.1 0.00036 20.2 0.0 8.5 11 0 0 11 11 11 2 PPR repeat MNE1 PF13762.6 KFP04809.1 - 0.11 12.4 0.2 1.3 9.0 0.0 2.8 2 2 1 3 3 3 0 Mitochondrial splicing apparatus component G10 PF01125.17 KFP04810.1 - 1e-53 181.0 8.5 1.1e-53 180.9 8.5 1.0 1 0 0 1 1 1 1 G10 protein PP28 PF10252.9 KFP04811.1 - 2.7e-30 104.6 15.8 2.7e-30 104.6 15.8 2.5 2 1 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 RPN2_C PF18004.1 KFP04811.1 - 0.0086 16.0 7.2 0.0086 16.0 7.2 2.3 1 1 1 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain Nop53 PF07767.11 KFP04811.1 - 3.8 6.8 32.8 4.5 6.6 32.8 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) WD40 PF00400.32 KFP04812.1 - 4e-12 46.4 9.6 3.3e-05 24.5 0.1 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP04812.1 - 1.3e-10 41.5 0.1 0.0017 18.6 0.0 3.1 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP04812.1 - 0.00016 21.6 0.6 0.12 12.2 0.1 2.7 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A GD_N PF16030.5 KFP04812.1 - 0.17 12.2 0.0 0.47 10.8 0.0 1.7 2 0 0 2 2 2 0 Serine protease gd N-terminus WD40 PF00400.32 KFP04813.1 - 1.5e-12 47.8 15.8 0.00015 22.5 0.5 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP04813.1 - 2.4e-11 43.8 0.7 0.026 14.8 0.0 3.8 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain LytB_WW PF18342.1 KFP04813.1 - 0.057 13.6 1.1 0.3 11.2 0.2 2.3 2 0 0 2 2 2 0 Endo-beta-N-acetylglucosaminidase LytB WW domain Arm PF00514.23 KFP04814.1 - 2e-78 256.3 14.7 2.9e-11 43.0 0.1 9.4 9 0 0 9 9 9 9 Armadillo/beta-catenin-like repeat IBB PF01749.20 KFP04814.1 - 3e-23 82.1 1.0 6.2e-23 81.1 1.0 1.6 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.6 KFP04814.1 - 1.3e-20 73.4 1.3 2.7e-07 30.9 0.0 5.6 5 1 1 6 6 6 4 HEAT-like repeat Arm_3 PF16186.5 KFP04814.1 - 2.7e-18 65.2 1.1 4.5e-18 64.5 0.2 1.8 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.6 KFP04814.1 - 1.2e-15 57.6 1.6 2.8e-05 24.4 0.0 6.0 3 2 4 7 7 7 5 HEAT repeats HEAT PF02985.22 KFP04814.1 - 4.1e-08 32.8 1.2 0.012 15.8 0.0 6.1 6 0 0 6 6 6 1 HEAT repeat V-ATPase_H_C PF11698.8 KFP04814.1 - 0.00049 20.2 0.9 3.2 7.9 0.1 3.6 3 1 1 4 4 4 2 V-ATPase subunit H HEAT_PBS PF03130.16 KFP04814.1 - 0.024 15.3 6.1 26 5.9 0.1 6.1 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat PXA PF02194.15 KFP04814.1 - 0.08 12.9 0.0 10 6.0 0.0 2.9 2 1 0 2 2 2 0 PXA domain CCD48 PF15799.5 KFP04815.1 - 9.1e-49 166.3 7.0 9.9e-49 166.1 7.0 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 CCD48 PF15799.5 KFP04816.1 - 2.9e-120 402.3 20.6 2e-76 257.6 14.8 2.0 1 1 1 2 2 2 2 Coiled-coil domain-containing protein 48 BLOC1_2 PF10046.9 KFP04816.1 - 0.0028 17.9 8.1 0.0038 17.5 5.1 2.2 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 EF-hand_7 PF13499.6 KFP04816.1 - 0.016 15.6 0.0 0.05 14.1 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair SIKE PF05769.11 KFP04816.1 - 0.04 13.8 7.6 0.1 12.5 0.3 2.3 2 0 0 2 2 2 0 SIKE family EF-hand_6 PF13405.6 KFP04816.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain DUF4633 PF15464.6 KFP04816.1 - 0.078 13.1 1.1 0.15 12.2 0.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4633) gpW PF02831.15 KFP04816.1 - 0.11 12.4 1.5 1.1 9.2 0.1 2.8 3 0 0 3 3 2 0 gpW PspA_IM30 PF04012.12 KFP04816.1 - 0.24 11.0 11.1 0.91 9.1 3.9 2.3 2 0 0 2 2 2 0 PspA/IM30 family Spc7 PF08317.11 KFP04816.1 - 0.3 9.9 12.4 0.49 9.2 12.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Hemerythrin PF01814.23 KFP04816.1 - 0.35 11.5 9.6 0.85 10.2 0.4 3.4 4 0 0 4 4 4 0 Hemerythrin HHE cation binding domain HisKA_3 PF07730.13 KFP04816.1 - 0.99 10.0 5.9 1.5 9.4 0.7 2.7 2 1 0 2 2 2 0 Histidine kinase COG2 PF06148.11 KFP04816.1 - 1.1 9.4 9.7 0.79 9.8 4.1 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ABC_tran_CTD PF16326.5 KFP04816.1 - 1.5 9.1 10.0 0.36 11.1 0.4 3.1 2 1 1 3 3 3 0 ABC transporter C-terminal domain DUF3958 PF13125.6 KFP04816.1 - 1.8 8.8 11.7 0.43 10.8 6.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) RasGAP_C PF03836.15 KFP04816.1 - 1.9 8.7 8.5 8.9 6.5 5.0 2.8 1 1 1 2 2 2 0 RasGAP C-terminus TMF_TATA_bd PF12325.8 KFP04816.1 - 1.9 8.7 16.6 3.8 7.8 8.7 2.4 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Med9 PF07544.13 KFP04816.1 - 1.9 8.6 11.2 14 5.8 0.1 2.9 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF4094 PF13334.6 KFP04816.1 - 2.8 8.4 5.5 5.4 7.5 4.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) Seryl_tRNA_N PF02403.22 KFP04816.1 - 3.9 7.7 8.7 3.4 7.9 5.0 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Cnn_1N PF07989.11 KFP04816.1 - 4.3 7.6 10.6 10 6.3 2.6 2.9 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 CENP-F_leu_zip PF10473.9 KFP04816.1 - 6.4 6.8 17.8 27 4.8 17.8 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Gla PF00594.20 KFP04816.1 - 6.6 7.0 10.6 29 5.0 5.0 2.7 2 0 0 2 2 2 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain Atg14 PF10186.9 KFP04816.1 - 7.8 5.5 11.8 15 4.6 11.8 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Acyl-CoA_dh_1 PF00441.24 KFP04818.1 - 2.4e-38 131.7 0.1 3.3e-33 115.0 0.1 2.7 2 1 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFP04818.1 - 3.4e-27 94.5 0.1 6.1e-27 93.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KFP04818.1 - 2.8e-24 85.9 0.0 7.4e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KFP04818.1 - 1.8e-07 31.5 0.0 1.4e-06 28.6 0.0 2.4 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain IQ_SEC7_PH PF16453.5 KFP04819.1 - 1.8e-67 225.6 2.1 4e-67 224.4 0.0 2.5 3 0 0 3 3 3 1 PH domain Sec7 PF01369.20 KFP04819.1 - 4.1e-63 212.4 0.1 8.9e-63 211.3 0.0 1.7 2 0 0 2 2 2 1 Sec7 domain bZIP_2 PF07716.15 KFP04820.1 - 0.00082 19.4 2.8 0.0013 18.8 2.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper NRBF2 PF08961.10 KFP04820.1 - 0.0024 17.5 1.4 0.0027 17.3 1.4 1.0 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator TSC22 PF01166.18 KFP04820.1 - 0.0038 17.5 1.0 0.0041 17.4 1.0 1.2 1 0 0 1 1 1 1 TSC-22/dip/bun family bZIP_1 PF00170.21 KFP04820.1 - 0.0093 16.0 2.1 0.0094 16.0 2.1 1.2 1 0 0 1 1 1 1 bZIP transcription factor DivIC PF04977.15 KFP04820.1 - 0.012 15.4 1.2 0.012 15.4 1.2 1.2 1 0 0 1 1 1 0 Septum formation initiator Phage_Gp23 PF10669.9 KFP04820.1 - 0.029 14.7 0.2 0.032 14.5 0.2 1.1 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) HSBP1 PF06825.12 KFP04820.1 - 0.041 13.8 0.1 0.054 13.4 0.1 1.3 1 0 0 1 1 1 0 Heat shock factor binding protein 1 BMFP PF04380.13 KFP04820.1 - 0.05 14.1 1.8 0.065 13.7 1.8 1.2 1 0 0 1 1 1 0 Membrane fusogenic activity ORF6C PF10552.9 KFP04820.1 - 0.063 13.4 1.0 0.062 13.4 1.0 1.0 1 0 0 1 1 1 0 ORF6C domain DUF4439 PF14530.6 KFP04820.1 - 0.079 13.7 0.0 0.09 13.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4439) Big_2 PF02368.18 KFP04821.1 - 2.9e-15 55.9 16.6 5.8e-13 48.5 0.1 5.2 7 0 0 7 7 7 2 Bacterial Ig-like domain (group 2) AlphaC_N PF08829.10 KFP04821.1 - 0.036 14.1 0.1 1.7 8.7 0.0 3.4 3 0 0 3 3 3 0 Alpha C protein N terminal Hist_deacetyl PF00850.19 KFP04822.1 - 1.8e-51 175.5 0.0 2.2e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Shisa PF13908.6 KFP04823.1 - 1.3e-18 67.9 10.8 1.3e-18 67.9 10.8 1.7 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator Comm PF15957.5 KFP04823.1 - 0.096 13.0 4.0 0.17 12.3 4.0 1.4 1 1 0 1 1 1 0 Commissureless Corona_S2 PF01601.16 KFP04823.1 - 3.3 6.1 6.6 3.9 5.8 6.6 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein BTG PF07742.12 KFP04824.1 - 6.1e-29 100.2 0.0 1e-28 99.5 0.0 1.3 2 0 0 2 2 2 1 BTG family Ins_P5_2-kin PF06090.12 KFP04825.1 - 4.6e-92 309.0 0.5 5.3e-92 308.8 0.5 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase zf-C3HC4 PF00097.25 KFP04825.1 - 0.16 11.9 1.7 0.61 10.0 1.7 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) LRR_8 PF13855.6 KFP04826.1 - 1.1e-51 172.4 17.3 2.9e-16 59.0 0.1 6.5 5 1 2 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 KFP04826.1 - 1e-29 102.0 29.4 1.2e-05 25.5 0.1 8.7 6 1 3 10 10 10 8 Leucine Rich repeats (2 copies) VWC PF00093.18 KFP04826.1 - 1.7e-10 41.1 14.5 3.5e-10 40.0 14.5 1.6 1 0 0 1 1 1 1 von Willebrand factor type C domain LRR_1 PF00560.33 KFP04826.1 - 2.3e-10 39.6 26.0 10 7.1 0.2 11.8 11 1 0 11 11 11 2 Leucine Rich Repeat LRR_9 PF14580.6 KFP04826.1 - 4.9e-10 39.2 7.1 0.00012 21.6 0.4 5.2 1 1 2 4 4 4 3 Leucine-rich repeat LRR_5 PF13306.6 KFP04826.1 - 4.2e-09 36.5 0.0 0.00028 20.8 0.0 3.1 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KFP04826.1 - 2.5e-07 30.2 20.7 0.15 12.2 0.0 9.6 11 0 0 11 11 11 2 Leucine Rich repeat Amnionless PF14828.6 KFP04826.1 - 0.13 11.1 11.1 0.2 10.4 11.1 1.2 1 0 0 1 1 1 0 Amnionless FNIP PF05725.12 KFP04826.1 - 0.24 11.6 12.7 7.2 6.9 0.3 4.7 4 1 0 4 4 4 0 FNIP Repeat LRR_8 PF13855.6 KFP04827.1 - 3.1e-70 231.8 48.7 8.3e-12 44.7 1.1 9.7 5 3 3 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 KFP04827.1 - 2.5e-36 123.1 61.8 0.00061 20.1 1.6 12.2 4 3 7 12 12 12 12 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP04827.1 - 2e-20 73.0 8.3 1.9e-06 27.8 0.0 5.9 2 2 3 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP04827.1 - 1.6e-13 50.6 29.4 0.00028 20.4 1.1 5.8 3 2 2 6 6 6 5 Leucine-rich repeat LRRNT PF01462.18 KFP04827.1 - 8.5e-12 44.4 31.3 2.6e-07 30.1 2.7 6.4 8 0 0 8 8 8 2 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KFP04827.1 - 2.3e-06 27.4 49.0 2 9.3 0.1 15.4 14 4 1 15 15 15 3 Leucine Rich Repeat LRR_6 PF13516.6 KFP04827.1 - 0.00097 19.0 43.0 7.2 6.9 0.1 13.3 15 0 0 15 15 15 3 Leucine Rich repeat FNIP PF05725.12 KFP04827.1 - 5.3 7.3 22.8 24 5.2 0.9 6.9 5 1 1 6 6 6 0 FNIP Repeat LRR_8 PF13855.6 KFP04828.1 - 2e-19 69.1 3.8 8.3e-08 31.9 0.0 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFP04828.1 - 7.3e-13 48.5 7.6 0.00025 21.4 0.1 4.2 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP04828.1 - 1.4e-06 28.3 0.5 0.0089 16.0 0.0 2.3 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFP04828.1 - 5.5e-06 26.2 3.6 4.5 8.2 0.1 5.7 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 KFP04828.1 - 0.0011 18.8 3.3 2.7 8.3 0.0 4.6 4 0 0 4 4 4 1 Leucine Rich repeat LRR_9 PF14580.6 KFP04828.1 - 0.059 12.9 1.6 0.5 9.9 1.3 2.1 1 1 0 1 1 1 0 Leucine-rich repeat CENP-P PF13096.6 KFP04829.1 - 1e-33 116.5 1.0 1.9e-33 115.7 1.0 1.4 1 0 0 1 1 1 1 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P Csm1_N PF18504.1 KFP04829.1 - 0.1 12.9 1.5 0.33 11.3 0.7 2.1 2 0 0 2 2 2 0 Csm1 N-terminal domain OmpH PF03938.14 KFP04829.1 - 0.36 11.2 3.8 0.54 10.6 3.8 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) T6PP_N PF18572.1 KFP04829.1 - 0.52 10.2 4.3 1.3 8.9 3.3 2.2 1 1 1 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain DUF1474 PF07342.11 KFP04829.1 - 0.68 10.5 6.5 2.4 8.7 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1474) Jnk-SapK_ap_N PF09744.9 KFP04829.1 - 0.78 9.9 5.6 1.5 9.1 5.7 1.5 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 SlyX PF04102.12 KFP04829.1 - 1.8 9.3 5.7 28 5.4 3.9 3.0 2 1 0 2 2 2 0 SlyX DUF4404 PF14357.6 KFP04829.1 - 2 9.1 4.7 2.2 9.0 1.3 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) zf-HC5HC2H PF13771.6 KFP04830.1 - 1.8e-06 28.1 0.6 1.8e-06 28.1 0.6 3.6 3 2 0 3 3 3 2 PHD-like zinc-binding domain zf-RING_2 PF13639.6 KFP04830.1 - 4.4e-05 23.7 9.6 4.4e-05 23.7 9.6 3.6 3 1 0 3 3 3 2 Ring finger domain zf-HC5HC2H_2 PF13832.6 KFP04830.1 - 0.0076 16.4 1.0 0.0076 16.4 1.0 3.3 2 1 1 3 3 3 2 PHD-zinc-finger like domain DUF2545 PF10810.8 KFP04830.1 - 0.08 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2545) zf-RING_11 PF17123.5 KFP04830.1 - 0.42 10.4 9.1 0.25 11.1 2.9 3.4 2 1 0 2 2 2 0 RING-like zinc finger SPRY PF00622.28 KFP04831.1 - 1.4e-26 92.9 0.1 2.9e-26 92.0 0.1 1.6 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.6 KFP04831.1 - 1.1e-08 34.8 8.3 1.1e-08 34.8 8.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP04831.1 - 0.0012 19.1 11.7 0.0032 17.8 11.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFP04831.1 - 0.017 15.0 14.0 0.047 13.6 14.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP04831.1 - 0.021 14.7 12.2 0.061 13.2 12.2 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP04831.1 - 0.029 14.4 9.9 0.085 12.8 9.9 1.9 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP04831.1 - 0.13 12.1 14.3 0.049 13.5 9.8 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KFP04831.1 - 2.3 8.4 8.0 1 9.5 5.1 1.9 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 KFP04831.1 - 4.9 7.3 12.0 11 6.1 12.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFP04831.1 - 7.2 6.9 10.7 20 5.5 10.7 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING NTP_transferase PF00483.23 KFP04832.1 - 2.1e-28 99.6 0.0 4e-28 98.6 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 KFP04832.1 - 3.8e-09 35.9 11.7 1e-08 34.6 5.5 3.2 1 1 1 2 2 2 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFP04832.1 - 1.5e-05 24.6 2.5 1.5e-05 24.6 2.5 2.9 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KFP04832.1 - 0.0088 14.2 0.3 0.013 13.7 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) IPK PF03770.16 KFP04833.1 - 7.8e-65 218.4 0.0 1.2e-64 217.8 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase E1_UFD PF09358.10 KFP04834.1 - 3.1e-11 43.8 0.0 3.5e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fold domain zinc_ribbon_13 PF09855.9 KFP04834.1 - 0.04 14.1 0.0 0.055 13.6 0.0 1.3 1 0 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) She9_MDM33 PF05546.11 KFP04834.1 - 0.04 13.7 0.1 0.044 13.6 0.1 1.1 1 0 0 1 1 1 0 She9 / Mdm33 family Phage_P2_GpE PF06528.12 KFP04834.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Phage P2 GpE HGWP PF03578.15 KFP04834.1 - 0.2 11.2 0.5 0.2 11.2 0.5 1.7 2 0 0 2 2 2 0 HGWP repeat ThiF PF00899.21 KFP04835.1 - 2.5e-78 262.8 0.0 6.8e-58 195.9 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KFP04835.1 - 7.8e-74 248.8 0.0 1.1e-73 248.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 KFP04835.1 - 4e-20 71.8 0.0 7e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 KFP04835.1 - 2.7e-16 59.5 0.4 6.4e-16 58.3 0.4 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Pyr_redox_2 PF07992.14 KFP04835.1 - 0.22 10.7 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NHL PF01436.21 KFP04835.1 - 3.6 7.8 4.5 9.5 6.5 0.2 3.3 3 0 0 3 3 3 0 NHL repeat DAG1 PF05454.11 KFP04837.1 - 2.2e-153 509.7 7.4 3.3e-153 509.1 7.4 1.3 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) a_DG1_N2 PF18424.1 KFP04837.1 - 6.8e-67 223.2 0.1 1.1e-66 222.5 0.1 1.4 1 0 0 1 1 1 1 Alpha-Dystroglycan N-terminal domain 2 TMEM154 PF15102.6 KFP04837.1 - 0.0049 16.8 0.1 0.0049 16.8 0.1 2.0 2 0 0 2 2 2 1 TMEM154 protein family Peptidase_S9 PF00326.21 KFP04838.1 - 1e-28 100.2 0.0 1.6e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KFP04838.1 - 4.4e-11 42.5 0.0 4e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFP04838.1 - 2.2e-10 40.6 0.0 7.3e-09 35.6 0.1 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 KFP04838.1 - 2.8e-05 23.8 0.0 5.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KFP04838.1 - 0.0005 19.8 0.0 0.55 9.8 0.0 2.2 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 KFP04838.1 - 0.014 15.1 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative esterase BAAT_C PF08840.11 KFP04838.1 - 0.068 13.1 0.0 0.19 11.6 0.0 1.7 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 KFP04838.1 - 0.19 11.4 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KFP04839.1 - 1.5e-35 122.6 0.0 2.3e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KFP04839.1 - 7.7e-11 42.1 0.2 8.9e-07 28.8 0.3 2.7 2 1 1 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFP04839.1 - 3.2e-10 39.7 0.0 4.3e-05 22.9 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 KFP04839.1 - 8.8e-07 28.7 0.0 3.6e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KFP04839.1 - 4.2e-06 26.8 0.0 8.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KFP04839.1 - 2.3e-05 24.1 0.0 0.2 11.2 0.0 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KFP04839.1 - 0.00021 22.0 7.8 0.00021 22.0 7.8 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family COesterase PF00135.28 KFP04839.1 - 0.00036 19.6 0.0 0.00055 18.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family BAAT_C PF08840.11 KFP04839.1 - 0.002 18.1 0.0 0.0045 16.9 0.0 1.4 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 KFP04839.1 - 0.019 14.6 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PhoPQ_related PF10142.9 KFP04839.1 - 0.04 12.6 0.0 0.062 12.0 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Esterase PF00756.20 KFP04839.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative esterase AXE1 PF05448.12 KFP04839.1 - 0.18 10.4 0.0 1.9 7.1 0.0 2.4 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 KFP04839.1 - 0.19 11.2 0.4 0.59 9.6 0.4 1.8 1 1 0 1 1 1 0 Esterase PHB depolymerase HIP1_clath_bdg PF16515.5 KFP04840.1 - 0.022 15.4 7.1 0.022 15.4 7.1 3.5 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4907 PF16250.5 KFP04840.1 - 0.054 13.4 0.0 0.18 11.7 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4907) GAS PF13851.6 KFP04840.1 - 0.11 11.8 37.0 0.61 9.4 14.0 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 KFP04840.1 - 0.15 12.2 28.0 0.28 11.4 18.5 2.3 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) MAD PF05557.13 KFP04840.1 - 0.35 9.2 31.6 0.96 7.7 31.3 1.7 1 1 0 1 1 1 0 Mitotic checkpoint protein KASH_CCD PF14662.6 KFP04840.1 - 0.62 9.9 37.2 3.5 7.4 7.6 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH IFT57 PF10498.9 KFP04840.1 - 0.64 8.9 24.4 0.033 13.2 7.6 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 T3SSipB PF16535.5 KFP04840.1 - 0.8 10.2 21.1 0.17 12.4 6.6 3.4 2 2 1 3 3 3 0 Type III cell invasion protein SipB HMMR_N PF15905.5 KFP04840.1 - 0.95 8.9 38.3 3.7 6.9 16.7 2.6 1 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal WEMBL PF05701.11 KFP04840.1 - 0.98 8.0 27.9 7.6 5.1 17.4 2.8 1 1 1 2 2 2 0 Weak chloroplast movement under blue light APG17 PF04108.12 KFP04840.1 - 1.2 8.2 18.7 2.3 7.2 6.7 2.5 1 1 1 2 2 2 0 Autophagy protein Apg17 Laminin_II PF06009.12 KFP04840.1 - 1.7 8.7 21.6 0.32 11.0 6.8 2.9 2 1 0 2 2 2 0 Laminin Domain II PI3K_P85_iSH2 PF16454.5 KFP04840.1 - 1.9 8.1 29.9 1.2 8.7 10.6 2.3 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain CHAD PF05235.14 KFP04840.1 - 2.3 8.1 10.9 0.18 11.7 4.9 2.0 1 1 1 2 2 2 0 CHAD domain Spc7 PF08317.11 KFP04840.1 - 2.3 7.0 34.4 0.66 8.8 14.1 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein RP-C_C PF11800.8 KFP04840.1 - 3 7.9 11.9 0.11 12.6 1.7 2.5 1 1 1 2 2 2 0 Replication protein C C-terminal region DUF3450 PF11932.8 KFP04840.1 - 3.6 6.8 22.5 1.1 8.5 2.4 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) CC2-LZ PF16516.5 KFP04840.1 - 7.8 6.9 26.1 1.1 9.6 6.0 3.0 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF87 PF01935.17 KFP04840.1 - 7.8 6.5 17.7 1 9.4 3.8 2.3 1 1 1 2 2 2 0 Helicase HerA, central domain Pkinase PF00069.25 KFP04841.1 - 6.3e-61 206.1 0.1 7.6e-61 205.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP04841.1 - 2.4e-23 82.8 0.0 3.1e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP04841.1 - 4.5e-06 26.2 0.0 0.00035 20.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KFP04841.1 - 0.023 14.0 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KFP04842.1 - 3.5e-87 291.9 0.0 4.7e-87 291.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP04842.1 - 2.7e-34 118.7 0.0 4.4e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Sema PF01403.19 KFP04842.1 - 1.5e-24 86.7 0.0 2.2e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Sema domain TIG PF01833.24 KFP04842.1 - 5.5e-22 77.7 0.1 6.2e-09 35.8 0.0 4.6 4 0 0 4 4 4 3 IPT/TIG domain PSI PF01437.25 KFP04842.1 - 0.0004 20.9 16.4 0.0004 20.9 16.4 2.3 2 0 0 2 2 2 1 Plexin repeat Kinase-like PF14531.6 KFP04842.1 - 0.051 12.9 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Mon1 PF03164.14 KFP04843.1 - 2.5e-144 481.3 0.2 2.9e-144 481.1 0.2 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 OCRE PF17780.1 KFP04844.1 - 4.9e-19 68.1 1.9 1.1e-18 67.0 1.9 1.6 1 0 0 1 1 1 1 OCRE domain G-patch PF01585.23 KFP04844.1 - 7.2e-05 22.6 0.8 0.0002 21.2 0.8 1.8 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 KFP04844.1 - 0.12 12.7 0.3 0.35 11.2 0.3 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding RRM_1 PF00076.22 KFP04844.1 - 0.15 11.9 0.0 8.3 6.3 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sema PF01403.19 KFP04845.1 - 2.3e-121 405.6 0.0 3.5e-69 233.7 0.0 2.1 2 0 0 2 2 2 2 Sema domain ig PF00047.25 KFP04845.1 - 1.1e-05 25.5 0.0 3e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFP04845.1 - 2.2e-05 25.0 0.0 5.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP04845.1 - 0.00021 21.3 0.0 0.00037 20.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain PSI PF01437.25 KFP04845.1 - 0.0031 18.0 10.2 0.011 16.3 10.2 2.0 1 0 0 1 1 1 1 Plexin repeat V-set PF07686.17 KFP04845.1 - 0.0098 16.1 0.1 0.063 13.4 0.1 2.2 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KFP04845.1 - 0.1 12.9 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain SNF2_N PF00176.23 KFP04846.1 - 8.2e-50 169.5 0.0 1.5e-49 168.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFP04846.1 - 7.8e-15 55.2 0.0 2.1e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP04846.1 - 6.3e-08 32.8 0.0 2.6e-07 30.8 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFP04846.1 - 0.00017 20.9 0.0 0.41 9.8 0.0 2.8 2 0 0 2 2 2 2 ERCC3/RAD25/XPB C-terminal helicase CdiA_C PF18451.1 KFP04846.1 - 0.0093 16.2 0.0 0.036 14.3 0.0 2.0 1 0 0 1 1 1 1 Contact-dependent growth inhibition CdiA C-terminal domain PI3K_1B_p101 PF10486.9 KFP04846.1 - 5.2 4.7 11.5 9.7 3.8 11.5 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SPOC PF07744.13 KFP04847.1 - 2.1e-35 121.9 0.0 3.1e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 SPOC domain RRM_1 PF00076.22 KFP04847.1 - 1.2e-25 89.1 0.0 2e-14 53.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFP04847.1 - 0.00027 20.9 0.0 0.0012 18.9 0.0 2.0 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 KFP04847.1 - 0.0013 18.7 0.0 0.0074 16.3 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KFP04847.1 - 0.035 14.2 0.0 3.3 7.9 0.0 2.8 2 0 0 2 2 2 0 RNA recognition motif Armet PF10208.9 KFP04848.1 - 1.1e-52 177.8 2.5 1.3e-52 177.6 2.5 1.0 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding Cauli_DNA-bind PF03310.13 KFP04848.1 - 0.029 14.4 1.3 0.053 13.6 1.3 1.4 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein HeH PF12949.7 KFP04848.1 - 0.03 14.0 0.1 0.061 13.0 0.1 1.6 1 0 0 1 1 1 0 HeH/LEM domain Epsilon_antitox PF08998.11 KFP04848.1 - 0.08 13.2 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial epsilon antitoxin Hamartin PF04388.12 KFP04848.1 - 0.1 11.3 0.0 0.12 11.0 0.0 1.0 1 0 0 1 1 1 0 Hamartin protein DHR-2 PF06920.13 KFP04849.1 - 5.5e-133 444.4 6.7 5.5e-133 444.4 6.7 2.4 3 0 0 3 3 3 1 Dock homology region 2 DOCK_N PF16172.5 KFP04849.1 - 1.4e-100 336.9 0.5 2.5e-100 336.1 0.5 1.4 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 KFP04849.1 - 1.3e-46 158.8 0.0 3.9e-46 157.3 0.0 1.8 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Pkinase PF00069.25 KFP04850.1 - 8.3e-69 231.9 0.0 1.4e-68 231.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP04850.1 - 2.4e-29 102.4 0.0 3.7e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFP04850.1 - 2.1e-07 30.5 0.1 3.9e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFP04850.1 - 0.0021 17.4 0.0 0.0055 16.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFP04850.1 - 0.0027 16.6 0.0 0.0069 15.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase VF530 PF09905.9 KFP04850.1 - 0.048 13.9 0.0 0.41 10.8 0.0 2.3 2 0 0 2 2 2 0 DNA-binding protein VF530 PAXIP1_C PF15364.6 KFP04850.1 - 0.049 13.9 0.7 0.33 11.3 0.2 2.5 3 0 0 3 3 3 0 PAXIP1-associated-protein-1 C term PTIP binding protein Choline_kinase PF01633.20 KFP04850.1 - 0.087 12.4 0.0 0.35 10.4 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase SH2 PF00017.24 KFP04851.1 - 3.5e-13 49.4 0.0 6.6e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.16 KFP04851.1 - 7.9e-12 45.3 0.7 2.9e-11 43.5 0.7 2.0 1 0 0 1 1 1 1 SOCS box SH2_2 PF14633.6 KFP04851.1 - 0.19 11.1 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 SH2 domain MTS PF05175.14 KFP04852.1 - 5.4e-12 45.6 0.0 3.1e-11 43.1 0.0 1.9 1 1 0 2 2 2 1 Methyltransferase small domain PrmC_N PF17827.1 KFP04852.1 - 1e-09 38.8 0.0 1.9e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 PrmC N-terminal domain Methyltransf_31 PF13847.6 KFP04852.1 - 1.1e-07 31.8 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP04852.1 - 1.8e-07 31.8 0.0 4.1e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFP04852.1 - 3.1e-07 30.1 0.0 4.8e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 KFP04852.1 - 1e-06 28.5 0.0 2.3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_4 PF02390.17 KFP04852.1 - 6.3e-06 25.8 0.0 2.1e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase UPF0020 PF01170.18 KFP04852.1 - 0.0002 21.1 0.1 0.00063 19.5 0.1 1.8 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 KFP04852.1 - 0.00061 20.5 0.0 0.0011 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP04852.1 - 0.00075 20.1 0.0 0.0015 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 KFP04852.1 - 0.0081 15.8 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_18 PF12847.7 KFP04852.1 - 0.0092 15.9 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KFP04852.1 - 0.0093 17.0 0.0 0.019 16.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 KFP04852.1 - 0.014 15.0 0.0 0.034 13.7 0.0 1.6 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase N6_N4_Mtase PF01555.18 KFP04852.1 - 0.024 14.4 0.0 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 DNA methylase PCMT PF01135.19 KFP04852.1 - 0.046 13.5 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 KFP04852.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_23 PF13489.6 KFP04852.1 - 0.14 11.9 0.0 0.46 10.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain PRMT5 PF05185.16 KFP04852.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase CEP19 PF14933.6 KFP04853.1 - 0.055 13.8 0.1 0.069 13.5 0.1 1.1 1 0 0 1 1 1 0 CEP19-like protein Gram_pos_anchor PF00746.21 KFP04853.1 - 0.059 13.3 0.3 0.09 12.7 0.3 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif LapA_dom PF06305.11 KFP04853.1 - 0.21 11.4 1.2 0.39 10.6 1.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain VWA PF00092.28 KFP04855.1 - 1.8e-09 38.1 0.0 2.2e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFP04855.1 - 4.5e-05 23.4 0.0 5.8e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFP04855.1 - 0.0081 16.8 0.0 0.032 14.9 0.0 1.8 1 1 1 2 2 2 1 von Willebrand factor type A domain VGCC_alpha2 PF08473.11 KFP04856.1 - 8.2e-134 446.6 0.4 3.7e-132 441.2 0.1 2.0 2 0 0 2 2 2 2 Neuronal voltage-dependent calcium channel alpha 2acd Cytochrom_B561 PF03188.16 KFP04857.1 - 7.5e-32 110.3 7.2 1.1e-31 109.8 7.2 1.2 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 IPTL-CTERM PF18203.1 KFP04857.1 - 7.9 6.5 11.4 0.36 10.8 4.8 2.3 2 0 0 2 2 2 0 IPTL-CTERM motif NPR2 PF06218.11 KFP04858.1 - 1.7e-77 261.0 6.7 5.8e-41 140.7 2.6 3.0 1 1 2 3 3 3 3 Nitrogen permease regulator 2 zf-MYND PF01753.18 KFP04859.1 - 1.1e-09 38.2 18.6 1.1e-09 38.2 18.6 2.1 2 0 0 2 2 2 1 MYND finger Mlh1_C PF16413.5 KFP04859.1 - 0.011 15.1 0.2 0.018 14.4 0.2 1.3 1 0 0 1 1 1 0 DNA mismatch repair protein Mlh1 C-terminus zf-HIT PF04438.16 KFP04859.1 - 0.14 12.1 7.6 0.25 11.3 7.6 1.4 1 0 0 1 1 1 0 HIT zinc finger RA PF00788.23 KFP04860.1 - 1.2e-16 61.1 1.7 2e-16 60.4 0.1 2.1 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain Nore1-SARAH PF16517.5 KFP04860.1 - 8.9e-16 57.5 2.0 8.9e-16 57.5 2.0 2.7 3 0 0 3 3 3 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Ras_bdg_2 PF14847.6 KFP04860.1 - 0.0092 16.3 0.0 0.075 13.4 0.0 2.0 2 0 0 2 2 2 1 Ras-binding domain of Byr2 Mst1_SARAH PF11629.8 KFP04860.1 - 0.066 13.3 0.5 0.2 11.8 0.5 1.8 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 FERM_N PF09379.10 KFP04860.1 - 0.08 12.9 0.0 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 FERM N-terminal domain TUSC2 PF15000.6 KFP04861.1 - 4.9e-33 113.7 0.1 5.4e-33 113.6 0.1 1.0 1 0 0 1 1 1 1 Tumour suppressor candidate 2 Glyco_hydro_56 PF01630.18 KFP04862.1 - 5.5e-145 482.6 0.3 6.4e-145 482.4 0.3 1.0 1 0 0 1 1 1 1 Hyaluronidase EGF PF00008.27 KFP04862.1 - 0.0071 16.6 4.0 0.14 12.5 0.2 2.6 2 0 0 2 2 2 2 EGF-like domain EGF_2 PF07974.13 KFP04862.1 - 0.72 10.3 13.5 3.1 8.2 4.5 2.6 2 0 0 2 2 2 0 EGF-like domain Glyco_hydro_56 PF01630.18 KFP04863.1 - 1.3e-130 435.3 0.0 1.5e-130 435.1 0.0 1.0 1 0 0 1 1 1 1 Hyaluronidase EGF_2 PF07974.13 KFP04863.1 - 0.025 14.9 9.4 0.23 11.9 0.9 2.4 2 0 0 2 2 2 0 EGF-like domain 6PF2K PF01591.18 KFP04864.1 - 2.5e-102 340.9 1.4 3.2e-102 340.6 0.7 1.5 2 0 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KFP04864.1 - 1.6e-42 145.4 0.0 2.2e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KFP04864.1 - 4.8e-08 33.3 0.0 1.2e-07 32.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain Prefoldin PF02996.17 KFP04864.1 - 0.00074 19.4 1.0 0.0012 18.7 0.0 1.9 2 0 0 2 2 2 1 Prefoldin subunit KTI12 PF08433.10 KFP04864.1 - 0.00079 18.9 0.1 0.0015 18.1 0.1 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 KFP04864.1 - 0.013 16.0 0.0 0.027 15.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain His_Phos_2 PF00328.22 KFP04864.1 - 0.028 13.8 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Zeta_toxin PF06414.12 KFP04864.1 - 0.073 12.3 0.0 0.23 10.7 0.0 2.0 1 1 0 1 1 1 0 Zeta toxin Pkinase PF00069.25 KFP04865.1 - 1.2e-61 208.4 0.0 1.7e-61 207.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP04865.1 - 6.3e-38 130.5 0.0 1.2e-37 129.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KFP04865.1 - 8.1e-32 108.9 20.4 3.6e-17 62.0 7.1 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KFP04865.1 - 1.1e-08 35.6 1.7 2.2e-08 34.7 1.7 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain C1_2 PF03107.16 KFP04865.1 - 3.4e-05 24.0 13.8 0.0012 19.1 3.1 2.5 2 0 0 2 2 2 2 C1 domain Kinase-like PF14531.6 KFP04865.1 - 0.00062 19.2 0.0 0.0015 17.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like zf-RING-like PF08746.11 KFP04865.1 - 0.00068 19.9 19.2 0.043 14.1 6.7 2.7 2 0 0 2 2 2 2 RING-like domain Zf_RING PF16744.5 KFP04865.1 - 0.0028 17.7 9.3 0.0029 17.7 1.5 2.4 2 0 0 2 2 2 1 KIAA1045 RING finger Haspin_kinase PF12330.8 KFP04865.1 - 0.019 13.9 0.1 0.048 12.6 0.1 1.6 1 1 0 1 1 1 0 Haspin like kinase domain zf-RING_9 PF13901.6 KFP04865.1 - 0.021 14.8 14.2 0.24 11.4 4.0 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon PHD PF00628.29 KFP04865.1 - 0.023 14.6 18.3 0.091 12.7 3.5 2.6 2 0 0 2 2 2 0 PHD-finger DUF2318 PF10080.9 KFP04865.1 - 0.046 13.9 11.0 0.044 13.9 1.6 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Pkinase_fungal PF17667.1 KFP04865.1 - 0.071 11.9 0.0 0.16 10.7 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KFP04865.1 - 0.15 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DZR PF12773.7 KFP04865.1 - 0.15 12.1 12.6 0.46 10.6 2.7 2.7 2 0 0 2 2 2 0 Double zinc ribbon Prok-RING_1 PF14446.6 KFP04865.1 - 0.23 11.4 13.0 1.7 8.6 3.0 2.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 CxC3 PF18804.1 KFP04865.1 - 0.8 9.6 6.0 1 9.2 0.5 3.0 3 0 0 3 3 3 0 CxC3 like cysteine cluster associated with KDZ transposases PADR1 PF08063.12 KFP04865.1 - 2 8.3 12.1 0.052 13.3 2.8 2.7 2 0 0 2 2 2 0 PADR1 (NUC008) domain FYVE_2 PF02318.16 KFP04865.1 - 3.4 7.9 10.1 2.7 8.2 2.0 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger zf-ACC PF17848.1 KFP04865.1 - 5.7 7.1 10.6 29 4.9 2.6 3.5 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain Rft-1 PF04506.13 KFP04866.1 - 3.5e-143 478.0 27.2 4e-143 477.9 27.2 1.0 1 0 0 1 1 1 1 Rft protein Phtf-FEM1B_bdg PF12129.8 KFP04866.1 - 0.094 12.5 4.0 0.11 12.3 2.0 2.2 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor Sec62 PF03839.16 KFP04866.1 - 0.31 10.5 7.7 0.047 13.2 3.4 1.8 2 0 0 2 2 2 0 Translocation protein Sec62 MBT PF02820.18 KFP04867.1 - 7.2e-89 292.2 0.9 2.3e-22 79.1 0.0 4.5 4 0 0 4 4 4 4 mbt repeat SLED PF12140.8 KFP04867.1 - 1.2e-39 135.2 0.0 2.8e-39 134.1 0.0 1.6 1 0 0 1 1 1 1 SLED domain SAM_1 PF00536.30 KFP04867.1 - 6.3e-10 39.3 0.0 1.2e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP04867.1 - 1.3e-06 28.5 0.0 3.4e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFP04867.1 - 0.00068 19.5 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_Ste50p PF09235.10 KFP04867.1 - 0.011 15.9 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Agenet PF05641.12 KFP04867.1 - 0.06 13.8 0.2 5 7.7 0.0 3.2 3 0 0 3 3 3 0 Agenet domain DUF4637 PF15470.6 KFP04867.1 - 5 6.8 9.9 12 5.6 9.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Nucleo_P87 PF07267.11 KFP04867.1 - 5.7 5.7 7.5 8.3 5.1 7.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 STIMATE PF12400.8 KFP04868.1 - 1.3e-27 96.8 4.6 1.3e-27 96.8 4.6 1.5 2 0 0 2 2 2 1 STIMATE family Mustang PF15682.5 KFP04869.1 - 1e-40 137.7 3.4 1.1e-40 137.6 3.4 1.0 1 0 0 1 1 1 1 Musculoskeletal, temporally activated-embryonic nuclear protein 1 VIT PF08487.10 KFP04870.1 - 5.6e-34 116.7 1.3 5.6e-34 116.7 1.3 2.0 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 KFP04870.1 - 8.5e-25 88.0 0.1 1.6e-24 87.1 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFP04870.1 - 5.2e-18 65.5 0.0 9.6e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFP04870.1 - 1.7e-15 57.6 0.7 1.3e-14 54.7 0.2 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KFP04870.1 - 2e-06 27.4 0.0 3.3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 KFP04870.1 - 7.2e-05 23.0 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus DUF2201 PF09967.9 KFP04870.1 - 0.022 14.9 0.1 0.057 13.6 0.1 1.7 1 0 0 1 1 1 0 VWA-like domain (DUF2201) Spectrin PF00435.21 KFP04870.1 - 0.041 14.4 2.2 0.3 11.6 0.4 2.5 2 0 0 2 2 2 0 Spectrin repeat DUF1194 PF06707.11 KFP04870.1 - 0.048 12.9 0.1 0.13 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) Ribosomal_TL5_C PF14693.6 KFP04870.1 - 0.13 12.6 0.1 28 5.2 0.1 2.7 2 0 0 2 2 2 0 Ribosomal protein TL5, C-terminal domain ITI_HC_C PF06668.12 KFP04871.1 - 6.5e-72 241.2 0.0 1.1e-71 240.4 0.0 1.4 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus VIT PF08487.10 KFP04871.1 - 5.5e-32 110.3 3.2 1.1e-31 109.2 3.2 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 KFP04871.1 - 8e-21 75.1 0.0 1.5e-20 74.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFP04871.1 - 6.2e-15 55.5 0.0 1.2e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFP04871.1 - 5.3e-11 43.1 0.0 1.5e-10 41.7 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 KFP04871.1 - 5.6e-05 23.4 0.0 0.0001 22.5 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_CoxE PF05762.14 KFP04871.1 - 0.024 14.0 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein SPC12 PF06645.13 KFP04872.1 - 1.5e-31 108.3 1.2 1.7e-31 108.1 1.2 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MFS_1 PF07690.16 KFP04872.1 - 0.0026 16.8 0.0 0.0028 16.6 0.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3169 PF11368.8 KFP04872.1 - 0.045 13.3 0.4 0.056 13.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) LapA_dom PF06305.11 KFP04872.1 - 2.1 8.2 3.7 14 5.6 0.6 2.1 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain Glyco_transf_8 PF01501.20 KFP04873.1 - 3.4e-58 197.2 0.1 4e-58 197.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KFP04873.1 - 0.0013 18.3 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 Glucosyltransferase 24 Glyco_tranf_2_3 PF13641.6 KFP04873.1 - 0.056 13.3 0.2 3.7 7.4 0.1 2.6 3 1 0 3 3 3 0 Glycosyltransferase like family 2 Synapsin_N PF10581.9 KFP04873.1 - 0.14 12.1 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 Synapsin N-terminal Bromodomain PF00439.25 KFP04874.1 - 7.1e-113 368.9 27.0 3.4e-23 81.5 0.1 6.8 6 0 0 6 6 6 6 Bromodomain BAH PF01426.18 KFP04874.1 - 1.1e-54 183.5 3.7 6.4e-29 100.3 1.4 2.9 2 0 0 2 2 2 2 BAH domain HMG_box PF00505.19 KFP04874.1 - 2.7e-14 53.3 0.6 2.7e-14 53.3 0.6 2.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP04874.1 - 1.5e-10 41.5 1.3 4.8e-10 39.9 1.3 1.9 1 0 0 1 1 1 1 HMG-box domain UPF0640 PF15114.6 KFP04875.1 - 2.1e-35 120.3 2.6 2.3e-35 120.2 2.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0640 5_nucleotid PF05761.14 KFP04876.1 - 1.7e-154 515.1 5.3 1.9e-154 514.9 5.3 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.6 KFP04876.1 - 0.0026 17.9 0.7 0.039 14.0 1.2 2.7 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase PX PF00787.24 KFP04878.1 - 4e-19 68.7 2.5 4.8e-19 68.4 2.5 1.0 1 0 0 1 1 1 1 PX domain EBV-NA3 PF05009.12 KFP04878.1 - 0.095 12.2 0.0 0.095 12.2 0.0 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) EF-hand_7 PF13499.6 KFP04879.1 - 1e-27 96.3 9.8 1.7e-16 60.4 6.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFP04879.1 - 1.1e-27 95.6 15.6 3.9e-15 55.4 0.4 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KFP04879.1 - 7.4e-26 87.7 24.1 3.3e-08 32.5 1.0 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 KFP04879.1 - 5.7e-21 72.6 15.6 3.2e-07 29.7 2.1 5.0 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFP04879.1 - 2.9e-15 55.0 20.4 1.1e-06 27.8 0.3 5.0 4 1 1 5 5 5 3 EF hand EF-hand_9 PF14658.6 KFP04879.1 - 6.1e-13 48.9 1.0 3.7e-06 27.2 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KFP04879.1 - 2.4e-06 27.5 7.4 0.023 14.6 0.1 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFP04879.1 - 4.3e-05 23.8 1.5 0.0012 19.1 0.4 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 KFP04879.1 - 0.0021 18.0 0.1 1.3 8.9 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF1707 PF08044.11 KFP04879.1 - 0.0041 17.1 0.5 1.8 8.7 0.1 3.3 3 1 1 4 4 4 1 Domain of unknown function (DUF1707) UPF0154 PF03672.13 KFP04879.1 - 0.0069 16.4 0.0 2.1 8.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) DUF5580 PF17743.1 KFP04879.1 - 0.015 13.9 0.0 0.018 13.6 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_10 PF14788.6 KFP04879.1 - 0.029 14.2 4.1 0.097 12.5 0.8 2.7 2 1 1 3 3 2 0 EF hand DUF1456 PF07308.13 KFP04879.1 - 0.03 14.6 2.3 2.5 8.5 0.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1456) EMG1 PF03587.14 KFP04879.1 - 0.074 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 EMG1/NEP1 methyltransferase PolyA_pol_arg_C PF12626.7 KFP04879.1 - 0.1 12.6 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus SapB_1 PF05184.15 KFP04879.1 - 0.14 12.2 0.3 9.6 6.3 0.0 3.0 3 0 0 3 3 3 0 Saposin-like type B, region 1 Syntaxin PF00804.25 KFP04879.1 - 0.16 11.6 2.3 1.7 8.3 0.4 2.2 2 0 0 2 2 2 0 Syntaxin RNA_pol_Rpb4 PF03874.16 KFP04879.1 - 0.8 10.0 3.7 22 5.4 0.1 2.5 3 0 0 3 3 3 0 RNA polymerase Rpb4 HSF_DNA-bind PF00447.17 KFP04880.1 - 9e-21 74.3 0.3 1.1e-20 74.1 0.3 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding DSPc PF00782.20 KFP04881.1 - 1.9e-43 147.5 0.0 2.5e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP04881.1 - 0.00034 20.3 0.0 0.00046 19.8 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KFP04881.1 - 0.0053 17.0 0.0 0.0087 16.4 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 KFP04881.1 - 0.021 14.9 0.0 0.03 14.4 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate WD40 PF00400.32 KFP04882.1 - 3.3e-64 211.3 22.4 1.5e-09 38.3 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP04882.1 - 8.3e-23 80.5 0.1 9.2e-05 22.7 0.0 6.7 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP04882.1 - 2.4e-11 43.9 0.2 8.1e-06 25.9 0.0 2.6 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFP04882.1 - 2.9e-11 42.9 2.8 0.0072 15.3 0.1 4.9 1 1 4 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KFP04882.1 - 2.2e-05 23.2 0.1 0.25 9.8 0.0 3.1 1 1 2 3 3 3 3 Cytochrome D1 heme domain Frtz PF11768.8 KFP04882.1 - 0.002 16.6 0.1 0.54 8.5 0.0 3.2 2 1 1 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Proteasome_A_N PF10584.9 KFP04882.1 - 0.0034 17.0 0.8 1 9.1 0.0 3.5 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature Syntaxin-6_N PF09177.11 KFP04882.1 - 0.0052 17.3 0.6 0.01 16.4 0.6 1.5 1 0 0 1 1 1 1 Syntaxin 6, N-terminal WD40_like PF17005.5 KFP04882.1 - 0.034 13.5 0.0 29 3.8 0.0 3.9 1 1 2 5 5 5 0 WD40-like domain DUF4908 PF16252.5 KFP04882.1 - 0.11 12.1 0.0 0.43 10.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4908) PD40 PF07676.12 KFP04882.1 - 0.12 12.3 1.2 2.2 8.3 0.0 3.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat CLZ PF16526.5 KFP04882.1 - 0.23 11.8 3.1 2.1 8.8 3.3 2.1 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Aminotran_1_2 PF00155.21 KFP04883.1 - 1.1e-78 264.9 0.0 1.6e-78 264.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Preseq_ALAS PF09029.10 KFP04883.1 - 3.3e-43 146.9 6.0 6.9e-43 145.9 6.0 1.6 1 0 0 1 1 1 1 5-aminolevulinate synthase presequence Cys_Met_Meta_PP PF01053.20 KFP04883.1 - 2.8e-07 29.4 0.0 2.2e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KFP04883.1 - 1.9e-05 23.8 0.0 3.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFP04883.1 - 0.00066 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KFP04883.1 - 0.011 15.1 0.3 0.035 13.4 0.3 1.8 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cofilin_ADF PF00241.20 KFP04884.1 - 2.6e-41 140.2 0.5 2.8e-22 78.8 0.6 2.7 3 0 0 3 3 3 2 Cofilin/tropomyosin-type actin-binding protein WD40 PF00400.32 KFP04884.1 - 4e-17 62.3 0.7 3.7e-05 24.4 0.0 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP04884.1 - 5e-10 39.5 0.0 0.00081 19.6 0.0 3.9 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain MinC_C PF03775.16 KFP04884.1 - 0.17 11.9 0.0 0.58 10.2 0.0 1.9 1 0 0 1 1 1 0 Septum formation inhibitor MinC, C-terminal domain PD40 PF07676.12 KFP04884.1 - 1.1 9.3 5.0 15 5.6 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PP2C PF00481.21 KFP04885.1 - 3.5e-34 118.6 0.0 2.6e-15 56.8 0.0 3.0 2 1 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 KFP04885.1 - 9.4e-05 22.4 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KFP04885.1 - 0.046 13.3 0.0 1.8 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein phosphatase 2C DUF4147 PF13660.6 KFP04886.1 - 9.2e-80 267.5 0.2 1.2e-79 267.1 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 KFP04886.1 - 8.9e-37 125.6 0.4 1.6e-36 124.8 0.4 1.4 1 0 0 1 1 1 1 MOFRL family Med23 PF11573.8 KFP04886.1 - 0.11 10.1 0.1 0.13 9.9 0.1 1.0 1 0 0 1 1 1 0 Mediator complex subunit 23 HAUS-augmin3 PF14932.6 KFP04887.1 - 1.5e-80 270.5 13.9 1.5e-80 270.5 13.9 3.8 3 1 1 4 4 4 1 HAUS augmin-like complex subunit 3 TetR_C_24 PF17932.1 KFP04887.1 - 0.075 13.3 0.4 0.075 13.3 0.4 2.9 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain DUF2129 PF09902.9 KFP04887.1 - 0.12 12.5 0.2 0.55 10.3 0.2 2.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2129) FDX-ACB PF03147.14 KFP04887.1 - 0.16 12.4 1.8 0.8 10.2 0.2 2.8 2 0 0 2 2 2 0 Ferredoxin-fold anticodon binding domain Fmp27_SW PF10305.9 KFP04887.1 - 0.17 12.6 1.5 1.4 9.7 0.0 2.9 3 0 0 3 3 3 0 RNA pol II promoter Fmp27 protein domain Sema PF01403.19 KFP04888.1 - 9.5e-144 479.3 0.0 1.2e-143 479.0 0.0 1.1 1 0 0 1 1 1 1 Sema domain ig PF00047.25 KFP04888.1 - 7.4e-05 22.8 0.0 0.00016 21.8 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFP04888.1 - 0.00029 21.4 0.0 0.00076 20.0 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP04888.1 - 0.00033 20.8 0.1 0.018 15.2 0.1 2.4 1 1 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFP04888.1 - 0.0043 17.1 0.0 0.0093 16.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain PSI PF01437.25 KFP04888.1 - 0.021 15.3 9.4 0.049 14.2 9.4 1.7 1 0 0 1 1 1 0 Plexin repeat Ig_2 PF13895.6 KFP04888.1 - 0.057 13.8 0.0 0.48 10.8 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin domain Act-Frag_cataly PF09192.10 KFP04888.1 - 0.27 10.6 0.1 0.43 9.9 0.1 1.2 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic Peptidase_M20 PF01546.28 KFP04889.1 - 1.3e-35 123.0 0.0 1.8e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFP04889.1 - 4.8e-13 49.0 0.0 8.2e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KFP04889.1 - 2.4e-05 24.1 0.0 3.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Abhydrolase_6 PF12697.7 KFP04890.1 - 4.3e-06 27.5 0.2 0.0014 19.3 0.3 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFP04890.1 - 4.3e-06 26.6 0.0 7.1e-05 22.6 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFP04890.1 - 0.0013 18.0 0.1 0.03 13.6 0.0 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 KFP04890.1 - 0.0056 16.3 0.0 0.0061 16.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 KFP04890.1 - 0.039 13.6 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KFP04890.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KFP04891.1 - 0.00043 20.0 0.1 0.0022 17.7 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 KFP04891.1 - 0.042 13.4 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family KH_1 PF00013.29 KFP04892.1 - 8.3e-47 156.9 14.0 5.5e-18 64.6 0.4 3.2 2 1 1 3 3 3 3 KH domain KH_2 PF07650.17 KFP04892.1 - 2.5e-11 43.3 5.4 0.00045 20.0 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KFP04892.1 - 2.9e-08 33.4 0.8 0.0094 15.8 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KFP04892.1 - 7.4e-05 22.8 8.1 1.1 9.4 0.2 3.3 2 1 1 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 KFP04892.1 - 0.0012 18.7 0.1 0.02 14.9 0.0 2.6 2 1 1 3 3 3 1 KH-like RNA-binding domain G-patch PF01585.23 KFP04893.1 - 4.3e-19 68.1 3.1 7.8e-19 67.3 3.1 1.5 1 0 0 1 1 1 1 G-patch domain OCRE PF17780.1 KFP04893.1 - 1.1e-18 67.0 18.5 1.1e-18 67.0 18.5 2.1 2 0 0 2 2 2 1 OCRE domain RRM_1 PF00076.22 KFP04893.1 - 3.2e-15 55.7 0.0 5.4e-08 32.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 KFP04893.1 - 7e-11 41.2 3.5 1.3e-10 40.4 3.5 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.7 KFP04893.1 - 4.9e-08 33.0 1.4 4.9e-08 33.0 1.4 2.5 3 0 0 3 3 3 1 G-patch domain GSIII_N PF12437.8 KFP04893.1 - 0.0011 18.6 0.5 0.0024 17.6 0.5 1.5 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal zf-C2HE PF16278.5 KFP04893.1 - 0.03 14.8 3.2 0.47 10.9 1.0 2.9 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger LegC3_N PF18654.1 KFP04893.1 - 0.67 9.1 11.5 0.053 12.7 1.3 2.3 2 0 0 2 2 2 0 LegC3 N-terminal coiled-coil domain Sema PF01403.19 KFP04894.1 - 3.4e-143 477.5 0.0 4.3e-143 477.2 0.0 1.1 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 KFP04894.1 - 0.0025 18.3 7.0 0.0078 16.7 7.0 1.9 1 0 0 1 1 1 1 Plexin repeat G-alpha PF00503.20 KFP04895.1 - 2.9e-120 401.7 2.1 3.5e-120 401.4 2.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFP04895.1 - 1.3e-14 54.0 2.9 4.8e-11 42.4 0.3 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFP04895.1 - 6e-05 22.5 0.8 0.069 12.5 0.2 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KFP04895.1 - 0.00032 20.9 0.3 0.37 11.0 0.0 2.7 1 1 2 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KFP04895.1 - 0.036 13.5 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NB-ARC PF00931.22 KFP04895.1 - 0.095 11.9 0.4 0.21 10.8 0.1 1.7 2 0 0 2 2 2 0 NB-ARC domain DAP3 PF10236.9 KFP04895.1 - 0.11 11.7 0.4 0.17 11.0 0.4 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 KFP04895.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 KFP04896.1 - 3.4e-117 391.6 3.9 3.9e-117 391.4 3.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFP04896.1 - 1e-13 51.2 0.1 9.4e-13 48.0 0.1 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family Aa_trans PF01490.18 KFP04897.1 - 1.8e-07 30.2 1.8 2.1e-07 30.0 1.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sema PF01403.19 KFP04898.1 - 4.6e-155 516.6 0.0 5.5e-155 516.3 0.0 1.1 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 KFP04898.1 - 0.0066 17.0 6.3 0.0066 17.0 6.3 2.5 3 0 0 3 3 3 1 Plexin repeat OAS1_C PF10421.9 KFP04899.1 - 1e-68 230.5 0.1 2.6e-68 229.2 0.0 1.7 2 0 0 2 2 2 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus ubiquitin PF00240.23 KFP04899.1 - 8.1e-24 83.2 0.3 3.1e-16 58.9 0.1 2.7 2 1 0 2 2 2 2 Ubiquitin family Ubiquitin_2 PF14560.6 KFP04899.1 - 4e-10 40.0 0.2 0.00053 20.4 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-like domain Rad60-SLD PF11976.8 KFP04899.1 - 4.1e-09 36.1 0.1 6.1e-06 26.0 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like NTP_transf_2 PF01909.23 KFP04899.1 - 3.7e-07 30.3 0.0 1.3e-06 28.6 0.0 2.0 1 0 0 1 1 1 1 Nucleotidyltransferase domain Ubiquitin_4 PF18036.1 KFP04899.1 - 0.045 13.8 0.0 10 6.3 0.0 2.8 2 0 0 2 2 2 0 Ubiquitin-like domain Glyco_transf_52 PF07922.11 KFP04899.1 - 0.11 11.7 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 52 SMODS PF18144.1 KFP04899.1 - 0.13 12.4 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain V-ATPase_H_N PF03224.14 KFP04899.1 - 0.14 11.4 0.1 2 7.6 0.0 2.1 2 0 0 2 2 2 0 V-ATPase subunit H IFRD PF05004.13 KFP04900.1 - 1.8e-85 286.8 0.1 2.1e-85 286.5 0.1 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.12 KFP04900.1 - 2.5e-21 76.0 0.3 2.5e-21 76.0 0.3 2.0 3 0 0 3 3 3 1 Interferon-related protein conserved region Glyco_hydro_56 PF01630.18 KFP04901.1 - 2.9e-126 421.0 0.0 3.3e-126 420.8 0.0 1.0 1 0 0 1 1 1 1 Hyaluronidase WD40 PF00400.32 KFP04902.1 - 2.1e-37 126.4 8.7 5.5e-06 27.0 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP04902.1 - 4.3e-06 27.0 0.0 0.026 14.8 0.0 4.4 2 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFP04902.1 - 0.11 11.8 0.0 0.29 10.4 0.0 1.7 1 1 0 1 1 1 0 WD40-like domain ANF_receptor PF01094.28 KFP04903.1 - 1.4e-100 336.8 0.1 1.8e-100 336.5 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 KFP04903.1 - 8.9e-61 205.6 16.6 1.4e-60 205.0 16.6 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 KFP04903.1 - 5.3e-13 48.7 10.1 1.6e-12 47.2 10.1 1.9 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.6 KFP04903.1 - 6.4e-10 39.2 0.6 1.1e-09 38.4 0.6 1.3 1 0 0 1 1 1 1 Periplasmic binding protein DUF543 PF04418.12 KFP04903.1 - 0.0078 16.2 0.3 1.3 9.1 0.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF543) PALP PF00291.25 KFP04903.1 - 0.16 11.4 0.1 0.33 10.3 0.1 1.5 1 1 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme GyrI-like PF06445.15 KFP04904.1 - 0.0042 17.4 0.0 0.0074 16.6 0.0 1.3 1 0 0 1 1 1 1 GyrI-like small molecule binding domain UCH PF00443.29 KFP04905.1 - 1.4e-85 286.9 0.1 2.4e-85 286.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_3 PF14836.6 KFP04905.1 - 2.3e-30 104.4 0.1 5.4e-30 103.2 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain DUSP PF06337.12 KFP04905.1 - 1.7e-22 79.8 0.3 5.1e-22 78.3 0.3 1.9 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 KFP04905.1 - 5.6e-16 59.0 0.2 5.5e-09 36.1 0.2 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 KFP04905.1 - 2e-07 30.9 0.0 1.6e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.8 KFP04905.1 - 5.4e-05 22.6 1.0 0.00043 19.7 0.3 2.5 3 0 0 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 EMC3_TMCO1 PF01956.16 KFP04906.1 - 1.9e-36 125.4 4.7 3.3e-36 124.6 0.3 2.1 2 0 0 2 2 2 2 Integral membrane protein EMC3/TMCO1-like Transket_pyr PF02779.24 KFP04907.1 - 7.5e-41 139.8 0.0 1.6e-40 138.7 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_N PF00456.21 KFP04907.1 - 1.6e-39 135.8 0.0 3.2e-39 134.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 KFP04907.1 - 1.9e-33 115.0 0.4 3.6e-33 114.1 0.4 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 KFP04907.1 - 2.8e-07 29.8 0.1 8.6e-07 28.2 0.0 1.8 2 0 0 2 2 2 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KFP04907.1 - 1.7e-05 24.6 0.1 0.00084 19.2 0.2 3.2 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KFP04907.1 - 2.4e-05 23.7 0.0 0.00089 18.5 0.0 2.4 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.10 KFP04907.1 - 0.0055 15.6 0.1 0.026 13.3 0.0 1.9 1 1 1 2 2 2 1 XFP N-terminal domain DCP1 PF06058.13 KFP04908.1 - 5.5e-27 94.0 0.0 1.2e-26 93.0 0.0 1.6 1 0 0 1 1 1 1 Dcp1-like decapping family mRNA_decap_C PF16741.5 KFP04908.1 - 7.9e-22 76.3 0.6 1.7e-21 75.3 0.6 1.6 1 0 0 1 1 1 1 mRNA-decapping enzyme C-terminus GMC_oxred_N PF00732.19 KFP04909.1 - 2.4e-96 322.6 0.0 3.2e-96 322.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFP04909.1 - 5.2e-40 137.3 0.0 8.6e-40 136.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KFP04909.1 - 3.7e-05 22.9 0.0 5.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KFP04909.1 - 0.0002 21.1 0.0 0.00031 20.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFP04909.1 - 0.00094 18.4 0.0 0.15 11.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KFP04909.1 - 0.0027 17.9 0.0 0.0084 16.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KFP04909.1 - 0.013 14.8 0.0 2.1 7.5 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFP04909.1 - 0.015 14.5 0.0 0.033 13.4 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Actin PF00022.19 KFP04910.1 - 4.9e-30 104.5 0.0 5.1e-15 55.0 0.0 2.8 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 KFP04910.1 - 1.7e-15 57.1 0.1 4.9e-08 32.6 0.1 2.1 2 0 0 2 2 2 2 Putative actin-like family SelK_SelG PF10961.8 KFP04911.1 - 3.1e-24 85.4 0.2 3.4e-24 85.3 0.2 1.0 1 0 0 1 1 1 1 Selenoprotein SelK_SelG VWA_N PF08399.11 KFP04912.1 - 2.2e-34 118.6 0.2 4.5e-34 117.6 0.2 1.6 1 0 0 1 1 1 1 VWA N-terminal VGCC_alpha2 PF08473.11 KFP04912.1 - 1.1e-26 93.6 3.7 2.2e-26 92.6 3.1 1.8 2 1 0 2 2 2 1 Neuronal voltage-dependent calcium channel alpha 2acd VWA_3 PF13768.6 KFP04912.1 - 4.6e-14 52.6 0.0 9.1e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain dCache_1 PF02743.18 KFP04912.1 - 9.8e-13 48.5 1.5 3.6e-11 43.3 0.0 3.1 3 1 0 3 3 3 1 Cache domain VWA PF00092.28 KFP04912.1 - 5.4e-12 46.3 0.1 9.9e-12 45.4 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFP04912.1 - 1.4e-09 38.6 0.0 2.6e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain dCache_2 PF08269.11 KFP04912.1 - 0.001 18.3 0.1 0.0037 16.5 0.1 1.8 2 0 0 2 2 2 1 Cache domain Cache_3-Cache_2 PF17201.4 KFP04912.1 - 0.0077 15.5 0.0 0.024 13.9 0.1 1.7 2 0 0 2 2 2 1 Cache 3/Cache 2 fusion domain VWA_CoxE PF05762.14 KFP04912.1 - 0.028 13.8 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein LRR_8 PF13855.6 KFP04913.1 - 1.9e-28 98.0 24.1 7e-16 57.7 4.7 4.0 2 1 2 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 KFP04913.1 - 2.4e-09 36.9 6.0 0.00012 21.6 0.9 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 KFP04913.1 - 1.7e-08 34.6 21.6 0.0011 19.4 2.1 3.5 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP04913.1 - 5.7e-07 29.5 0.0 2.1e-06 27.7 0.1 1.7 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFP04913.1 - 1.3e-05 25.1 14.7 0.046 14.3 0.2 5.1 5 0 0 5 5 5 2 Leucine Rich Repeat LRRNT PF01462.18 KFP04913.1 - 0.0011 18.6 1.7 0.0011 18.6 1.7 2.1 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 KFP04913.1 - 0.0063 16.5 10.8 0.2 11.8 0.1 4.2 4 0 0 4 4 4 1 Leucine Rich repeat RVT_1 PF00078.27 KFP04914.1 - 0.073 12.6 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) wnt PF00110.19 KFP04915.1 - 6.5e-122 406.9 23.3 7.5e-122 406.7 23.3 1.0 1 0 0 1 1 1 1 wnt family EndoU_bacteria PF14436.6 KFP04915.1 - 0.15 12.4 0.0 0.51 10.7 0.0 1.8 1 1 0 1 1 1 0 Bacterial EndoU nuclease K_channel_TID PF07941.11 KFP04915.1 - 3.3 8.2 6.8 1.4 9.4 0.2 2.7 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain Cast PF10174.9 KFP04916.1 - 0 1246.7 155.3 0 1061.5 125.1 2.0 2 0 0 2 2 2 2 RIM-binding protein of the cytomatrix active zone PKcGMP_CC PF16808.5 KFP04916.1 - 0.00038 20.3 1.0 0.00038 20.3 1.0 13.7 13 2 2 16 16 16 3 Coiled-coil N-terminus of cGMP-dependent protein kinase MAD PF05557.13 KFP04916.1 - 0.00082 17.9 28.6 0.00082 17.9 28.6 6.1 2 1 4 6 6 6 3 Mitotic checkpoint protein ATG16 PF08614.11 KFP04916.1 - 0.00083 19.6 36.7 0.0026 18.0 14.9 9.7 2 2 7 9 9 9 4 Autophagy protein 16 (ATG16) AAA_13 PF13166.6 KFP04916.1 - 0.0015 17.3 23.7 0.0015 17.3 23.7 4.9 1 1 3 5 5 5 2 AAA domain Lebercilin PF15619.6 KFP04916.1 - 0.0078 15.9 15.6 0.0078 15.9 15.6 8.0 2 2 2 6 6 6 3 Ciliary protein causing Leber congenital amaurosis disease CCDC66 PF15236.6 KFP04917.1 - 3.1e-50 170.0 38.5 3.1e-50 170.0 38.5 4.5 5 0 0 5 5 5 2 Coiled-coil domain-containing protein 66 DUF3715 PF12509.8 KFP04918.1 - 1e-55 187.9 0.0 3.4e-55 186.2 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3715) RhoGEF PF00621.20 KFP04919.1 - 1.4e-39 136.2 0.4 2.5e-39 135.4 0.1 1.6 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.6 KFP04919.1 - 1.2e-06 28.7 0.5 1.1e-05 25.6 0.5 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFP04919.1 - 0.00022 21.7 0.2 0.0009 19.7 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 KFP04919.1 - 0.00033 20.5 0.3 0.0042 16.9 0.2 2.6 1 1 1 2 2 2 1 Pleckstrin homology domain PH_16 PF17838.1 KFP04919.1 - 0.029 14.2 0.6 0.58 10.0 0.6 2.4 1 1 0 1 1 1 0 PH domain zf-Di19 PF05605.12 KFP04919.1 - 0.86 9.9 3.6 0.34 11.2 0.4 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding IL17R_D_N PF16742.5 KFP04920.1 - 8.7e-65 216.3 0.1 1.7e-64 215.4 0.1 1.5 1 0 0 1 1 1 1 N-terminus of interleukin 17 receptor D SEFIR PF08357.11 KFP04920.1 - 1e-56 191.4 0.7 2.2e-56 190.3 0.7 1.6 1 0 0 1 1 1 1 SEFIR domain TIR_2 PF13676.6 KFP04920.1 - 0.0014 19.3 0.0 0.0038 17.8 0.0 1.8 1 1 0 1 1 1 1 TIR domain fn3 PF00041.21 KFP04920.1 - 0.027 14.8 0.0 8.5 6.8 0.0 2.7 3 0 0 3 3 3 0 Fibronectin type III domain DUF2141 PF09912.9 KFP04920.1 - 0.072 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2141) Homeodomain PF00046.29 KFP04921.1 - 8.3e-24 83.2 0.4 1.7e-23 82.2 0.4 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP04921.1 - 0.0048 16.8 0.2 0.011 15.6 0.0 1.7 2 0 0 2 2 2 1 Homeobox KN domain BAR_3 PF16746.5 KFP04922.1 - 8.1e-55 186.1 11.2 8.1e-55 186.1 11.2 2.2 2 0 0 2 2 2 1 BAR domain of APPL family PID PF00640.23 KFP04922.1 - 1.7e-12 47.6 1.6 6.8e-12 45.6 0.0 2.9 2 1 1 3 3 3 1 Phosphotyrosine interaction domain (PTB/PID) PH PF00169.29 KFP04922.1 - 1.8e-07 31.6 0.1 7e-06 26.5 0.0 2.7 2 0 0 2 2 2 1 PH domain PTB PF08416.13 KFP04922.1 - 0.0028 17.8 0.0 0.0096 16.1 0.0 1.9 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PH_9 PF15410.6 KFP04922.1 - 0.0091 16.4 0.6 0.07 13.5 0.0 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain Gemin6 PF06372.12 KFP04922.1 - 0.056 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Gemin6 protein DUF1664 PF07889.12 KFP04922.1 - 0.45 10.6 7.2 7.3 6.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Ank_2 PF12796.7 KFP04923.1 - 4.6e-49 164.9 5.0 3.1e-11 43.7 0.0 6.2 1 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP04923.1 - 5.6e-41 138.4 8.7 5.8e-10 39.5 0.0 8.1 6 2 2 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP04923.1 - 3.7e-40 131.3 13.4 0.00023 21.4 0.0 11.2 11 0 0 11 11 11 10 Ankyrin repeat Ank PF00023.30 KFP04923.1 - 1.5e-31 107.4 16.0 0.00012 22.4 0.0 10.1 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 KFP04923.1 - 4.1e-22 78.0 19.4 9.1e-06 25.9 0.0 9.2 4 2 7 11 11 11 6 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFP04923.1 - 4.5e-11 42.9 6.5 4.5e-11 42.9 6.5 2.3 2 0 0 2 2 2 1 SOCS box Exo_endo_phos PF03372.23 KFP04924.1 - 6e-22 78.3 0.0 1.4e-21 77.1 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Arf PF00025.21 KFP04925.1 - 1.8e-72 242.4 0.2 2e-72 242.3 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFP04925.1 - 2e-14 53.5 0.0 2.2e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP04925.1 - 3.7e-14 53.0 0.0 5.1e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFP04925.1 - 5.6e-13 48.7 0.0 6.6e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFP04925.1 - 9.7e-11 41.4 1.0 1.7e-09 37.3 0.3 2.4 1 1 1 2 2 2 1 G-protein alpha subunit Gtr1_RagA PF04670.12 KFP04925.1 - 2.4e-10 40.2 0.0 2.7e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP04925.1 - 1.7e-05 24.8 0.0 2.5e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KFP04925.1 - 0.1 11.9 0.1 0.15 11.4 0.1 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase SPA PF08616.10 KFP04926.1 - 1.3e-16 60.6 0.2 2.9e-15 56.2 0.0 2.5 2 0 0 2 2 2 1 Stabilization of polarity axis DENN PF02141.21 KFP04926.1 - 7.8e-07 29.2 3.2 7.8e-07 29.2 3.2 2.2 2 1 0 2 2 2 1 DENN (AEX-3) domain Avl9 PF09794.9 KFP04926.1 - 0.0018 17.0 0.0 0.0036 16.0 0.0 1.5 1 0 0 1 1 1 1 Transport protein Avl9 RAM PF15320.6 KFP04926.1 - 0.2 12.3 0.1 0.42 11.3 0.1 1.5 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein FHA PF00498.26 KFP04927.1 - 7e-18 64.8 0.1 2.7e-17 62.9 0.0 2.1 2 0 0 2 2 2 1 FHA domain Tropomyosin PF00261.20 KFP04927.1 - 0.0024 17.3 31.2 0.0024 17.3 31.2 4.8 2 2 1 3 3 3 1 Tropomyosin GAS PF13851.6 KFP04927.1 - 0.0029 17.0 116.9 0.025 13.9 11.1 6.7 3 2 2 6 6 6 4 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 KFP04927.1 - 0.0046 17.2 9.5 0.0046 17.2 9.5 6.1 2 2 3 6 6 6 4 Fibrinogen alpha/beta chain family Lectin_N PF03954.14 KFP04927.1 - 0.0073 16.0 5.2 0.0073 16.0 5.2 6.7 3 3 3 6 6 6 3 Hepatic lectin, N-terminal domain T3SSipB PF16535.5 KFP04927.1 - 0.011 16.2 7.9 0.011 16.2 7.9 5.9 2 2 3 6 6 6 0 Type III cell invasion protein SipB DUF3138 PF11336.8 KFP04927.1 - 0.89 8.1 4.5 0.3 9.6 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Filamin PF00630.19 KFP04928.1 - 0 1255.3 50.1 5e-20 72.2 0.0 24.1 24 0 0 24 24 24 24 Filamin/ABP280 repeat CH PF00307.31 KFP04928.1 - 9.9e-18 64.3 0.0 1.8e-14 53.8 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain Y_Y_Y PF07495.13 KFP04928.1 - 1.3e-17 63.5 23.1 0.42 10.6 0.0 14.3 16 0 0 16 16 16 5 Y_Y_Y domain Big_3_5 PF16640.5 KFP04928.1 - 1.7e-16 60.2 28.0 0.11 12.7 1.5 14.0 14 0 0 14 14 14 4 Bacterial Ig-like domain (group 3) Invasin_D3 PF09134.10 KFP04928.1 - 2.9e-13 49.9 21.5 0.027 14.8 0.0 10.7 13 1 0 13 13 12 5 Invasin, domain 3 DUF5060 PF16586.5 KFP04928.1 - 6.1e-12 45.7 1.3 2.2 8.7 0.0 11.9 15 0 0 15 15 15 3 Domain of unknown function (DUF5060) YtkA PF13115.6 KFP04928.1 - 9.3e-09 35.8 13.9 1.9 9.1 0.1 12.5 15 0 0 15 15 14 1 YtkA-like DUF2141 PF09912.9 KFP04928.1 - 0.00011 22.0 0.8 48 3.9 0.0 6.6 7 0 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2141) BatD PF13584.6 KFP04928.1 - 0.00036 19.5 1.2 0.99 8.1 0.0 3.8 5 0 0 5 5 5 2 Oxygen tolerance EMP24_GP25L PF01105.24 KFP04928.1 - 0.00068 19.6 0.0 60 3.5 0.0 6.9 8 0 0 8 8 8 0 emp24/gp25L/p24 family/GOLD Big_1 PF02369.16 KFP04928.1 - 0.0078 16.2 5.8 60 3.7 0.1 7.7 8 0 0 8 8 8 0 Bacterial Ig-like domain (group 1) PapC_N PF13954.6 KFP04928.1 - 0.016 15.2 0.0 9.5 6.2 0.0 5.2 6 0 0 6 6 6 0 PapC N-terminal domain PEGA PF08308.11 KFP04928.1 - 0.25 11.3 4.9 1.2e+02 2.6 0.2 7.1 7 0 0 7 7 7 0 PEGA domain Exo_endo_phos PF03372.23 KFP04929.1 - 7.3e-12 45.3 0.0 9.1e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KFP04929.1 - 0.15 11.9 0.1 0.32 10.8 0.1 1.7 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Abhydrolase_1 PF00561.20 KFP04930.1 - 9.9e-24 84.4 0.0 2.2e-16 60.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFP04930.1 - 1.5e-20 74.7 0.0 3e-20 73.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFP04930.1 - 4e-15 55.7 0.0 9.9e-15 54.5 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KFP04930.1 - 9.9e-06 24.5 0.0 4.4e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 Ndr family DUF1057 PF06342.12 KFP04930.1 - 0.0027 16.8 0.0 0.0036 16.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Thioesterase PF00975.20 KFP04930.1 - 0.0074 16.4 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain UPF0227 PF05728.12 KFP04930.1 - 0.0086 16.0 0.2 3.5 7.5 0.0 2.4 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0227) FSH1 PF03959.13 KFP04930.1 - 0.017 14.8 0.1 1.4 8.5 0.0 2.5 2 1 1 3 3 3 0 Serine hydrolase (FSH1) Palm_thioest PF02089.15 KFP04930.1 - 0.034 14.0 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Ser_hydrolase PF06821.13 KFP04930.1 - 0.18 11.6 0.0 6.2 6.6 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase IPK PF03770.16 KFP04931.1 - 1.7e-64 217.4 0.6 1.7e-64 217.4 0.6 1.6 2 0 0 2 2 2 1 Inositol polyphosphate kinase DUF2013 PF09431.10 KFP04932.1 - 5e-34 117.4 0.3 1.2e-33 116.2 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Rcd1 PF04078.13 KFP04932.1 - 0.083 12.2 2.7 1.1 8.5 0.1 3.0 2 1 1 3 3 3 0 Cell differentiation family, Rcd1-like DUF1646 PF07854.12 KFP04932.1 - 0.15 11.4 0.1 0.58 9.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1646) Cadherin PF00028.17 KFP04933.1 - 4.7e-143 466.1 18.0 4.7e-22 78.3 0.1 8.5 8 0 0 8 8 8 8 Cadherin domain Sulfate_transp PF00916.20 KFP04933.1 - 7.7e-110 367.2 19.1 7.7e-110 367.2 19.1 1.8 2 0 0 2 2 2 1 Sulfate permease family GAIN PF16489.5 KFP04933.1 - 6.5e-62 208.7 0.0 1.1e-61 207.9 0.0 1.4 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain 7tm_2 PF00002.24 KFP04933.1 - 9.6e-49 165.9 16.1 9.6e-49 165.9 16.1 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Laminin_G_2 PF02210.24 KFP04933.1 - 4.7e-46 156.5 1.8 6.4e-27 94.6 0.0 3.4 4 0 0 4 4 4 2 Laminin G domain Laminin_G_1 PF00054.23 KFP04933.1 - 3.1e-27 95.4 0.1 2.4e-18 66.6 0.0 3.8 3 1 0 3 3 3 2 Laminin G domain STAS PF01740.21 KFP04933.1 - 2.6e-22 78.7 0.2 6.5e-22 77.4 0.0 1.8 2 0 0 2 2 1 1 STAS domain Cadherin_3 PF16184.5 KFP04933.1 - 2.6e-14 53.2 18.6 0.013 15.5 0.3 7.5 7 0 0 7 7 7 4 Cadherin-like EGF PF00008.27 KFP04933.1 - 3.4e-12 46.4 119.7 1.5e-07 31.6 7.3 9.3 10 1 0 10 10 8 5 EGF-like domain hEGF PF12661.7 KFP04933.1 - 5.9e-09 36.2 81.9 0.0066 17.0 6.2 9.3 8 0 0 8 8 8 4 Human growth factor-like EGF Laminin_EGF PF00053.24 KFP04933.1 - 4.5e-08 33.1 13.0 4.5e-08 33.1 13.0 8.3 6 2 2 8 8 8 2 Laminin EGF domain GPS PF01825.21 KFP04933.1 - 9e-07 29.3 4.4 9e-07 29.3 4.4 3.1 3 0 0 3 3 1 1 GPCR proteolysis site, GPS, motif Cadherin_2 PF08266.12 KFP04933.1 - 6.7e-06 25.8 0.1 11 6.0 0.0 6.7 7 0 0 7 7 7 1 Cadherin-like Cadherin_4 PF17803.1 KFP04933.1 - 0.00019 22.0 32.7 0.38 11.4 0.4 8.2 8 0 0 8 8 8 2 Bacterial cadherin-like domain Dicty_CAR PF05462.11 KFP04933.1 - 1 8.4 11.2 0.22 10.6 7.6 1.6 2 0 0 2 2 2 0 Slime mold cyclic AMP receptor GPS2_interact PF15784.5 KFP04933.1 - 1.3 9.5 6.3 4 7.9 6.3 1.7 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Peptidase_M16 PF00675.20 KFP04934.1 - 4.2e-50 169.6 0.0 6.5e-50 169.0 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFP04934.1 - 2.7e-36 125.3 0.0 1.6e-35 122.8 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain Alpha_Helical PF18489.1 KFP04934.1 - 0.11 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha helical domain PvlArgDC PF01862.16 KFP04934.1 - 0.14 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Adaptin_N PF01602.20 KFP04935.1 - 1.4e-135 452.9 10.4 1.7e-135 452.5 10.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KFP04935.1 - 2.4e-40 138.1 0.1 6e-40 136.8 0.1 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KFP04935.1 - 4.9e-38 129.8 0.0 1e-37 128.8 0.0 1.6 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KFP04935.1 - 3.1e-18 66.0 0.1 3.7e-08 33.6 0.0 6.3 4 2 3 7 7 7 3 HEAT repeats Cnd1 PF12717.7 KFP04935.1 - 9.8e-12 45.2 13.0 0.0089 16.1 0.3 5.3 3 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFP04935.1 - 9.1e-06 25.5 4.0 8.7 6.9 0.0 7.0 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.6 KFP04935.1 - 4e-05 24.0 0.7 0.49 10.9 0.1 4.0 4 0 0 4 4 3 2 HEAT-like repeat MOR2-PAG1_C PF14225.6 KFP04935.1 - 0.053 13.4 0.2 0.13 12.1 0.2 1.6 1 0 0 1 1 1 0 Cell morphogenesis C-terminal HEAT_PBS PF03130.16 KFP04935.1 - 0.07 13.8 1.4 28 5.8 0.0 4.6 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Arm PF00514.23 KFP04935.1 - 0.08 13.0 0.1 6.6 6.9 0.0 4.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 KFP04935.1 - 0.26 11.2 3.4 0.44 10.5 0.2 3.0 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central SRAP PF02586.14 KFP04936.1 - 4e-67 226.0 0.0 5.9e-67 225.4 0.0 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Linker_histone PF00538.19 KFP04937.1 - 1.1e-10 41.7 0.1 2.3e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family Ras PF00071.22 KFP04938.1 - 1.6e-58 196.9 0.1 1.9e-58 196.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP04938.1 - 2.3e-32 111.7 0.0 3.8e-32 111.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP04938.1 - 2.5e-13 49.9 0.1 3e-13 49.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP04938.1 - 2.4e-07 30.8 0.0 4.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP04938.1 - 2.6e-06 27.5 0.2 0.0033 17.3 0.1 2.2 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KFP04938.1 - 3.5e-06 26.5 0.0 4.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFP04938.1 - 1.2e-05 25.0 0.0 0.00077 19.0 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.19 KFP04938.1 - 0.0026 17.4 0.0 0.0096 15.5 0.0 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 KFP04938.1 - 0.0028 17.0 0.6 0.021 14.1 0.1 2.1 2 1 0 2 2 2 1 Septin ATP_bind_1 PF03029.17 KFP04938.1 - 0.0031 17.3 0.3 0.084 12.6 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KFP04938.1 - 0.0051 17.1 0.0 0.014 15.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 KFP04938.1 - 0.0053 16.5 0.0 0.12 12.1 0.1 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KFP04938.1 - 0.012 15.2 0.1 0.019 14.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KFP04938.1 - 0.015 15.0 0.1 0.027 14.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 KFP04938.1 - 0.016 14.7 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KFP04938.1 - 0.019 15.3 0.1 0.036 14.4 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 KFP04938.1 - 0.023 14.6 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.14 KFP04938.1 - 0.025 14.6 0.0 0.041 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 KFP04938.1 - 0.04 13.1 1.2 0.3 10.2 0.2 2.2 2 1 1 3 3 3 0 G-protein alpha subunit TniB PF05621.11 KFP04938.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein ATPase_2 PF01637.18 KFP04938.1 - 0.07 13.0 0.7 0.11 12.3 0.1 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KFP04938.1 - 0.087 12.0 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 KFP04938.1 - 0.089 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KFP04938.1 - 0.18 12.4 0.1 0.5 10.9 0.0 1.7 2 0 0 2 2 2 0 ABC transporter Ribophorin_I PF04597.14 KFP04939.1 - 4.9e-136 454.4 6.9 6.1e-136 454.1 6.9 1.1 1 0 0 1 1 1 1 Ribophorin I DNA_repr_REX1B PF14966.6 KFP04939.1 - 0.001 19.7 0.4 0.0027 18.3 0.4 1.7 1 0 0 1 1 1 1 DNA repair REX1-B GATA PF00320.27 KFP04940.1 - 1.7e-29 101.1 19.2 1e-14 53.8 6.3 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KFP04940.1 - 0.00081 18.9 10.9 0.063 12.8 0.5 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding DUF2387 PF09526.10 KFP04940.1 - 0.24 11.6 7.9 6.5 7.0 1.1 3.2 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) TDP43_N PF18694.1 KFP04940.1 - 0.25 11.2 0.2 5.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain Zn-ribbon_8 PF09723.10 KFP04940.1 - 0.69 10.1 6.5 3.9 7.7 0.6 2.8 2 1 0 2 2 2 0 Zinc ribbon domain Auto_anti-p27 PF06677.12 KFP04940.1 - 2.1 8.5 8.4 3.2 8.0 0.3 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Prim_Zn_Ribbon PF08273.12 KFP04940.1 - 6.9 7.0 12.9 0.39 11.0 1.9 2.8 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase GTP_EFTU PF00009.27 KFP04941.1 - 3.7e-15 56.0 0.0 6.5e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KFP04941.1 - 1.1e-07 32.2 0.1 2.8e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 cobW PF02492.19 KFP04941.1 - 7e-05 22.5 0.1 0.00011 21.9 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain FliS_cochap PF16522.5 KFP04941.1 - 0.019 14.9 1.0 0.046 13.7 0.3 1.9 2 0 0 2 2 2 0 Flagellar FLiS export co-chaperone, HP1076 RsgA_GTPase PF03193.16 KFP04941.1 - 0.038 13.9 1.1 0.32 10.9 0.0 2.4 3 0 0 3 3 3 0 RsgA GTPase Gtr1_RagA PF04670.12 KFP04941.1 - 0.059 12.7 0.4 0.29 10.5 0.4 2.1 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region TIP49 PF06068.13 KFP04942.1 - 2.2e-156 520.5 0.3 2.7e-156 520.2 0.3 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KFP04942.1 - 2.1e-27 95.0 0.1 5.8e-27 93.6 0.1 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KFP04942.1 - 3.3e-13 50.2 0.3 2.4e-08 34.5 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFP04942.1 - 5.4e-09 36.0 0.1 1.6e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFP04942.1 - 2e-06 28.1 0.1 0.1 12.9 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KFP04942.1 - 3.7e-05 23.7 0.1 0.0036 17.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFP04942.1 - 4e-05 24.1 0.0 0.00037 20.9 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KFP04942.1 - 0.00013 21.6 0.0 0.00077 19.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KFP04942.1 - 0.00028 20.6 0.1 0.3 10.8 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.6 KFP04942.1 - 0.00083 19.7 1.8 0.024 15.0 1.8 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFP04942.1 - 0.0011 19.5 0.0 0.0092 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KFP04942.1 - 0.0014 18.1 0.1 0.081 12.3 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KFP04942.1 - 0.0021 17.9 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 KFP04942.1 - 0.0021 18.3 0.1 0.004 17.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KFP04942.1 - 0.0026 17.1 0.0 0.0055 16.1 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Zeta_toxin PF06414.12 KFP04942.1 - 0.0092 15.3 0.2 0.028 13.7 0.1 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 KFP04942.1 - 0.01 16.0 0.0 0.026 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 KFP04942.1 - 0.01 15.3 0.1 0.033 13.6 0.1 1.8 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 KFP04942.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ResIII PF04851.15 KFP04942.1 - 0.012 15.6 0.1 0.39 10.7 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 KFP04942.1 - 0.014 14.9 0.1 0.056 13.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_11 PF13086.6 KFP04942.1 - 0.018 14.8 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KFP04942.1 - 0.019 14.9 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KFP04942.1 - 0.027 14.2 0.1 0.71 9.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KFP04942.1 - 0.029 13.7 1.1 0.18 11.1 0.0 2.5 3 0 0 3 3 3 0 KaiC AAA_14 PF13173.6 KFP04942.1 - 0.045 13.8 0.0 7.4 6.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KFP04942.1 - 0.063 12.5 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.17 KFP04942.1 - 0.068 12.2 0.1 0.13 11.4 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DNA_pol3_delta2 PF13177.6 KFP04942.1 - 0.071 12.9 0.0 1.9 8.2 0.0 2.2 2 1 0 2 2 2 0 DNA polymerase III, delta subunit AAA_lid_4 PF17864.1 KFP04942.1 - 0.071 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 RuvB AAA lid domain RNA_helicase PF00910.22 KFP04942.1 - 0.083 13.3 0.0 0.21 12.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase SecY PF00344.20 KFP04943.1 - 7.1e-77 258.7 12.0 9.5e-77 258.3 12.0 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KFP04943.1 - 8.2e-19 67.2 0.2 2.4e-18 65.7 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p YlaH PF14036.6 KFP04943.1 - 0.11 12.8 3.3 1.9 8.8 0.2 3.2 3 0 0 3 3 3 0 YlaH-like protein DUF2975 PF11188.8 KFP04943.1 - 0.25 11.2 9.1 0.065 13.1 0.7 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF2975) Kelch_1 PF01344.25 KFP04944.1 - 2.9e-33 113.2 11.0 4.3e-12 45.4 0.0 5.2 5 1 0 5 5 5 4 Kelch motif BACK PF07707.15 KFP04944.1 - 3.4e-29 101.0 1.3 3.4e-29 101.0 1.3 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFP04944.1 - 3.7e-24 84.2 5.9 3.6e-09 36.6 0.0 5.5 3 2 2 5 5 5 3 Kelch motif BTB PF00651.31 KFP04944.1 - 4.6e-24 84.8 2.8 4.6e-24 84.8 2.8 1.9 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 KFP04944.1 - 8.8e-16 57.2 4.8 1.6e-07 31.0 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 KFP04944.1 - 2.3e-14 53.1 2.3 0.00045 20.2 0.0 5.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP04944.1 - 1.2e-10 41.1 1.4 0.00011 22.1 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 KFP04944.1 - 2.3e-10 40.5 2.5 0.0019 18.4 0.0 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain DUF3342 PF11822.8 KFP04944.1 - 2.1e-05 24.6 0.6 0.00032 20.8 0.3 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3342) Trypsin PF00089.26 KFP04945.1 - 3.3e-60 203.7 0.6 3.6e-60 203.5 0.6 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFP04945.1 - 0.04 14.8 0.0 0.053 14.4 0.0 1.2 1 0 0 1 1 1 0 Trypsin-like peptidase domain C1-set PF07654.15 KFP04946.1 - 9e-17 61.2 0.0 1.1e-16 61.0 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.6 KFP04946.1 - 0.0016 19.0 0.0 0.0019 18.8 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP04947.1 - 6.5e-14 52.0 0.1 8.1e-14 51.7 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP04947.1 - 0.0015 19.0 0.0 0.0024 18.4 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Pkinase_Tyr PF07714.17 KFP04948.1 - 1.7e-95 319.2 0.0 2.3e-95 318.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.19 KFP04948.1 - 6.6e-70 234.8 0.1 1e-69 234.1 0.1 1.3 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.25 KFP04948.1 - 1.4e-45 155.7 0.0 2.1e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 KFP04948.1 - 4.5e-25 87.8 0.8 4.6e-14 52.5 0.1 3.2 3 0 0 3 3 3 2 Fibronectin type III domain SAM_2 PF07647.17 KFP04948.1 - 1.9e-20 72.7 0.0 3.6e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFP04948.1 - 9.1e-19 67.7 0.1 2.1e-18 66.5 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EphA2_TM PF14575.6 KFP04948.1 - 8.7e-18 65.0 0.0 1.8e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Ephrin_rec_like PF07699.13 KFP04948.1 - 5.1e-06 26.1 1.9 5.1e-06 26.1 1.9 2.6 2 1 0 2 2 2 1 Putative ephrin-receptor like Pur_ac_phosph_N PF16656.5 KFP04948.1 - 0.00021 21.8 0.1 0.0012 19.4 0.1 2.3 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Caskin1-CID PF16600.5 KFP04948.1 - 0.0073 16.9 0.1 0.026 15.1 0.1 2.0 1 0 0 1 1 1 1 Caskin1 CASK-interaction domain cEGF PF12662.7 KFP04948.1 - 0.024 14.5 0.6 0.085 12.8 0.6 1.9 1 0 0 1 1 1 0 Complement Clr-like EGF-like Kdo PF06293.14 KFP04948.1 - 0.07 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFP04948.1 - 0.078 11.9 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Interfer-bind PF09294.10 KFP04948.1 - 0.13 12.6 0.0 2.3 8.5 0.0 2.7 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III Pkinase_fungal PF17667.1 KFP04948.1 - 0.13 11.0 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase EGF_CA PF07645.15 KFP04948.1 - 3.9 7.8 8.4 12 6.2 0.5 2.7 2 0 0 2 2 2 0 Calcium-binding EGF domain Ank_2 PF12796.7 KFP04949.1 - 1.6e-23 83.1 9.2 2.8e-11 43.8 1.9 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP04949.1 - 1.8e-17 61.6 3.8 0.00013 22.1 0.1 5.9 5 0 0 5 5 5 4 Ankyrin repeat Ion_trans PF00520.31 KFP04949.1 - 3.6e-15 55.8 19.3 1.3e-12 47.5 19.3 2.3 1 1 0 1 1 1 1 Ion transport protein Ank_4 PF13637.6 KFP04949.1 - 2.5e-14 53.4 1.7 0.00017 22.1 0.0 4.9 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP04949.1 - 3.7e-13 49.4 5.1 0.083 13.2 0.1 5.3 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KFP04949.1 - 1.6e-11 44.1 3.3 0.014 15.9 0.2 5.1 5 0 0 5 5 5 3 Ankyrin repeat OKR_DC_1 PF01276.20 KFP04949.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain DSBA PF01323.20 KFP04950.1 - 6.9e-36 123.8 0.0 8.2e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Rap_GAP PF02145.15 KFP04951.1 - 1.7e-65 220.1 0.0 2.7e-65 219.4 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP GoLoco PF02188.17 KFP04951.1 - 0.00014 21.3 1.6 0.00029 20.2 1.6 1.6 1 0 0 1 1 1 1 GoLoco motif TMEM51 PF15345.6 KFP04952.1 - 0.083 12.7 2.6 0.1 12.4 2.6 1.3 1 1 0 1 1 1 0 Transmembrane protein 51 Peptidase_C14 PF00656.22 KFP04953.1 - 1.3e-43 149.8 0.4 1.1e-42 146.7 0.3 1.9 2 0 0 2 2 2 1 Caspase domain CARD PF00619.21 KFP04953.1 - 9.6e-19 67.2 0.5 2.2e-18 66.0 0.5 1.7 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 KFP04953.1 - 6.6e-07 29.2 0.5 1.2e-06 28.4 0.5 1.5 1 0 0 1 1 1 1 Caspase recruitment domain Yae1_N PF09811.9 KFP04954.1 - 6.1e-12 45.0 34.1 3.6e+02 1.0 34.1 3.5 1 1 0 1 1 1 0 Essential protein Yae1, N terminal FAM131 PF15010.6 KFP04955.1 - 1.3e-97 327.3 11.8 2.6e-97 326.3 11.8 1.4 1 1 0 1 1 1 1 Putative cell signalling LIM PF00412.22 KFP04956.1 - 6.1e-34 116.0 34.0 5.5e-13 48.9 8.8 3.3 3 0 0 3 3 3 3 LIM domain zf_C2H2_13 PF18508.1 KFP04956.1 - 0.043 13.4 1.7 0.072 12.7 0.2 2.2 2 0 0 2 2 2 0 Zinc finger domain DUF2321 PF10083.9 KFP04956.1 - 5.8 6.5 16.9 8.5 6.0 7.8 2.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Pkinase_Tyr PF07714.17 KFP04957.1 - 3.6e-97 324.7 0.0 5.6e-97 324.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.19 KFP04957.1 - 6.3e-52 176.2 1.0 9.6e-52 175.6 1.0 1.3 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.25 KFP04957.1 - 5.5e-48 163.6 0.0 8e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 KFP04957.1 - 7.3e-23 80.7 0.0 2.9e-10 40.3 0.0 2.8 3 0 0 3 3 2 2 Fibronectin type III domain SAM_1 PF00536.30 KFP04957.1 - 5e-21 74.9 0.0 1.1e-20 73.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP04957.1 - 1.1e-17 63.9 0.0 2.2e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EphA2_TM PF14575.6 KFP04957.1 - 8.5e-15 55.4 0.0 1.6e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Pur_ac_phosph_N PF16656.5 KFP04957.1 - 5.2e-08 33.4 0.0 3.3e-05 24.4 0.0 2.7 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Ephrin_rec_like PF07699.13 KFP04957.1 - 1.5e-06 27.8 3.1 1.5e-06 27.8 3.1 3.0 2 1 1 3 3 3 1 Putative ephrin-receptor like Tissue_fac PF01108.17 KFP04957.1 - 0.012 15.4 0.0 0.66 9.8 0.0 2.4 2 0 0 2 2 2 0 Tissue factor Haspin_kinase PF12330.8 KFP04957.1 - 0.028 13.4 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KFP04957.1 - 0.037 13.4 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFP04957.1 - 0.21 10.3 0.0 0.32 9.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase PMP1_2 PF08114.11 KFP04957.1 - 0.35 10.6 3.0 23 4.8 0.0 2.5 2 0 0 2 2 2 0 ATPase proteolipid family 7tm_4 PF13853.6 KFP04958.1 - 7.6e-39 134.1 20.7 9.3e-39 133.8 20.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP04958.1 - 2.8e-20 72.7 15.5 4.9e-20 72.0 15.5 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Gaa1 PF04114.14 KFP04958.1 - 3.9 6.4 12.6 11 4.9 12.6 1.7 1 1 0 1 1 1 0 Gaa1-like, GPI transamidase component TPR_1 PF00515.28 KFP04959.1 - 3.3e-24 83.7 1.4 3.3e-06 26.7 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFP04959.1 - 4.3e-20 70.2 5.2 0.00016 21.5 0.4 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFP04959.1 - 1.7e-18 66.0 0.3 3.3e-05 23.5 0.2 5.4 3 1 3 6 6 6 3 TPR repeat TPR_16 PF13432.6 KFP04959.1 - 2.4e-18 66.5 1.8 3.8e-06 27.5 0.4 4.7 2 2 1 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFP04959.1 - 5e-17 60.6 0.1 0.00082 19.4 0.0 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 KFP04959.1 - 2.6e-15 55.6 0.6 0.046 14.1 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFP04959.1 - 1.4e-14 53.5 14.2 0.012 16.4 0.2 8.1 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFP04959.1 - 4.8e-13 49.4 3.7 0.0026 18.2 0.0 4.8 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFP04959.1 - 2e-10 40.8 5.6 9.2e-05 22.7 0.1 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFP04959.1 - 9.4e-09 34.7 4.9 0.25 11.4 0.0 6.2 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_20 PF14561.6 KFP04959.1 - 7.9e-08 32.5 1.7 0.13 12.6 0.1 5.0 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFP04959.1 - 1.1e-06 28.7 6.8 0.058 13.5 0.2 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFP04959.1 - 9.9e-06 25.9 4.2 4.1 8.2 0.1 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFP04959.1 - 1.2e-05 25.0 4.7 0.05 13.5 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP04959.1 - 1.5e-05 25.1 2.4 0.065 13.5 0.1 3.0 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 MAS20 PF02064.15 KFP04959.1 - 0.03 14.4 0.7 4.4 7.4 0.0 3.1 2 2 1 3 3 3 0 MAS20 protein import receptor Secretin_N_2 PF07655.13 KFP04959.1 - 0.047 14.2 0.1 0.12 12.9 0.1 1.7 1 0 0 1 1 1 0 Secretin N-terminal domain DUF1641 PF07849.11 KFP04959.1 - 0.062 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) TPR_4 PF07721.14 KFP04959.1 - 0.075 13.7 0.5 1.3e+02 3.7 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 KFP04959.1 - 0.18 12.2 4.8 3 8.3 0.0 4.0 4 1 0 4 4 4 0 Bacterial transcriptional activator domain Mito_carr PF00153.27 KFP04960.1 - 4.4e-62 206.1 0.3 3.7e-21 74.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Lipocalin_7 PF14651.6 KFP04961.1 - 0.021 14.8 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family CUB PF00431.20 KFP04962.1 - 1.1e-51 173.7 0.2 7.9e-28 97.0 0.0 2.4 2 0 0 2 2 2 2 CUB domain Trypsin PF00089.26 KFP04962.1 - 2.9e-50 171.1 0.0 4.6e-50 170.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin Sushi PF00084.20 KFP04962.1 - 2.5e-15 56.8 15.8 4.1e-09 36.9 1.7 3.7 3 0 0 3 3 3 2 Sushi repeat (SCR repeat) FXa_inhibition PF14670.6 KFP04962.1 - 1.5e-10 41.2 7.9 8.6e-10 38.7 6.3 2.8 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 KFP04962.1 - 0.0001 22.4 8.7 0.00013 22.0 6.0 2.7 2 0 0 2 2 2 1 Calcium-binding EGF domain cEGF PF12662.7 KFP04962.1 - 0.00024 21.0 6.0 0.0011 18.9 3.0 3.0 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF PF00008.27 KFP04962.1 - 0.0021 18.3 4.9 0.01 16.1 4.9 2.2 1 0 0 1 1 1 1 EGF-like domain CUB_2 PF02408.20 KFP04962.1 - 0.007 16.1 0.2 1.6 8.5 0.0 3.0 3 0 0 3 3 3 1 CUB-like domain Trypsin_2 PF13365.6 KFP04962.1 - 0.098 13.6 0.0 0.22 12.4 0.0 1.7 1 0 0 1 1 1 0 Trypsin-like peptidase domain HRM PF02793.22 KFP04962.1 - 0.22 11.8 7.1 5.7 7.3 1.2 3.6 3 0 0 3 3 3 0 Hormone receptor domain hEGF PF12661.7 KFP04962.1 - 0.81 10.4 7.7 0.19 12.4 2.9 2.6 2 0 0 2 2 2 0 Human growth factor-like EGF Trypsin PF00089.26 KFP04963.1 - 6.1e-33 114.5 0.0 6.7e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 KFP04964.1 - 6.1e-19 68.4 1.1 2.1e-18 66.6 0.1 2.1 2 0 0 2 2 2 1 CUB domain FXa_inhibition PF14670.6 KFP04964.1 - 5e-09 36.3 6.5 9.3e-09 35.4 6.5 1.5 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 KFP04964.1 - 3e-06 27.3 9.0 5.9e-06 26.4 9.0 1.5 1 0 0 1 1 1 1 Calcium-binding EGF domain EGF PF00008.27 KFP04964.1 - 0.01 16.1 9.6 0.022 15.0 9.6 1.6 1 0 0 1 1 1 0 EGF-like domain CUB_2 PF02408.20 KFP04964.1 - 0.037 13.8 1.0 0.094 12.5 1.0 2.0 1 1 0 1 1 1 0 CUB-like domain MBOAT PF03062.19 KFP04965.1 - 1.4e-62 212.1 12.9 1.4e-62 212.1 12.9 2.1 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family EMG1 PF03587.14 KFP04966.1 - 1.1e-65 220.9 0.0 1.3e-65 220.7 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Band_7 PF01145.25 KFP04967.1 - 4.6e-17 62.6 5.0 4.6e-17 62.6 5.0 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family Med2 PF11214.8 KFP04967.1 - 0.00029 20.9 1.9 0.00056 20.0 1.9 1.4 1 0 0 1 1 1 1 Mediator complex subunit 2 Y_phosphatase PF00102.27 KFP04968.1 - 1.7e-78 263.4 0.3 2.9e-78 262.7 0.3 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase SH2 PF00017.24 KFP04968.1 - 6.8e-47 157.5 0.8 2e-22 79.1 0.0 2.9 3 0 0 3 3 3 2 SH2 domain DSPc PF00782.20 KFP04968.1 - 1.7e-05 24.6 0.1 7.2e-05 22.6 0.1 2.0 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP04968.1 - 0.0007 19.6 0.0 0.0024 17.9 0.0 1.9 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFP04968.1 - 0.022 14.9 0.9 0.06 13.5 0.0 2.3 3 0 0 3 3 3 0 Inositol hexakisphosphate MRNIP PF15749.5 KFP04968.1 - 0.065 14.0 0.3 0.065 14.0 0.3 2.4 2 0 0 2 2 2 0 MRN-interacting protein Enolase_C PF00113.22 KFP04969.1 - 4e-158 525.3 0.0 5e-158 525.0 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KFP04969.1 - 1.1e-59 200.3 0.0 2e-59 199.5 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KFP04969.1 - 2.8e-09 36.9 0.0 4.1e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KFP04969.1 - 3.5e-05 23.1 0.3 7.7e-05 22.0 0.3 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus LRR_4 PF12799.7 KFP04970.1 - 6.1e-20 71.0 35.7 8.2e-07 29.3 2.7 6.3 4 2 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP04970.1 - 1.8e-17 63.4 12.5 2.6e-15 56.3 3.9 3.1 1 1 1 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 KFP04970.1 - 1.2e-16 60.2 32.0 2.2e-07 30.5 2.8 5.7 2 1 2 5 5 5 5 Leucine rich repeat LRR_6 PF13516.6 KFP04970.1 - 1.3e-07 31.0 15.6 1.8 8.8 0.1 8.0 8 0 0 8 8 8 4 Leucine Rich repeat LRR_3 PF07725.12 KFP04970.1 - 0.013 15.3 5.9 3.9 7.5 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat TIM PF00121.18 KFP04971.1 - 3.8e-88 295.0 0.2 4.3e-88 294.8 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase WD40 PF00400.32 KFP04972.1 - 3.3e-43 144.8 19.3 3.9e-07 30.6 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP04972.1 - 3.5e-16 59.3 0.0 0.00097 19.4 0.1 5.7 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP04972.1 - 5.4e-08 32.9 0.0 0.036 14.0 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KFP04972.1 - 2.9e-06 26.8 0.1 0.0017 17.8 0.0 3.2 1 1 2 3 3 3 2 WD40-like domain Cytochrom_D1 PF02239.16 KFP04972.1 - 0.024 13.2 0.0 0.12 10.9 0.0 2.0 3 0 0 3 3 3 0 Cytochrome D1 heme domain 2OG-FeII_Oxy_3 PF13640.6 KFP04973.1 - 8.3e-10 39.4 0.0 2e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KFP04973.1 - 4e-05 24.0 0.0 0.00011 22.7 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KFP04973.1 - 0.017 15.7 0.0 0.044 14.5 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF2524 PF10732.9 KFP04973.1 - 0.12 12.7 0.3 0.48 10.8 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) TPR_6 PF13174.6 KFP04973.1 - 0.37 11.5 4.2 1.3 9.8 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat V-set PF07686.17 KFP04974.1 - 5.5e-14 52.3 2.6 0.00029 21.0 0.2 4.2 4 1 0 4 4 4 3 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP04974.1 - 6.7e-10 39.4 0.6 0.41 11.3 0.0 4.5 4 0 0 4 4 4 4 Immunoglobulin domain Izumo-Ig PF16706.5 KFP04974.1 - 1.9e-08 34.3 0.0 0.065 13.3 0.0 4.4 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain Ig_2 PF13895.6 KFP04974.1 - 3.6e-08 33.6 2.5 0.3 11.5 0.0 4.3 3 1 1 4 4 4 3 Immunoglobulin domain Tcell_CD4_C PF12104.8 KFP04974.1 - 7.2e-08 32.2 15.1 1.3e-07 31.4 15.1 1.5 1 0 0 1 1 1 1 T cell CD4 receptor C terminal region I-set PF07679.16 KFP04974.1 - 2.3e-07 30.8 0.5 0.59 10.2 0.0 4.5 4 2 1 5 5 5 3 Immunoglobulin I-set domain CD4-extracel PF09191.10 KFP04974.1 - 1.7e-06 28.4 0.3 4.4e-06 27.1 0.3 1.7 1 0 0 1 1 1 1 CD4, extracellular ig PF00047.25 KFP04974.1 - 2.7e-06 27.4 7.5 1.6 8.9 0.1 4.8 5 1 0 5 5 4 3 Immunoglobulin domain Ig_6 PF18452.1 KFP04974.1 - 3.5e-05 23.3 0.3 0.22 11.1 0.0 3.6 3 0 0 3 3 3 1 Immunoglobulin domain C2-set PF05790.15 KFP04974.1 - 0.0017 18.5 1.0 0.67 10.2 0.0 3.5 4 0 0 4 4 4 1 Immunoglobulin C2-set domain IgaA PF07095.11 KFP04974.1 - 0.039 12.0 0.2 0.9 7.4 0.0 2.0 2 0 0 2 2 2 0 Intracellular growth attenuator protein IgaA Egh16-like PF11327.8 KFP04974.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.5 1 1 0 1 1 1 0 Egh16-like virulence factor Ig_3 PF13927.6 KFP04975.1 - 5.3e-10 39.8 0.0 1.7e-06 28.5 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP04975.1 - 9.7e-10 38.7 0.1 3.8e-06 27.2 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP04975.1 - 1.1e-09 38.3 0.1 0.0027 17.8 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFP04975.1 - 1.6e-09 37.9 0.3 0.00027 21.1 0.0 3.0 2 1 1 3 3 3 2 Immunoglobulin V-set domain I-set PF07679.16 KFP04975.1 - 1.1e-08 35.1 0.0 0.00019 21.4 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Receptor_2B4 PF11465.8 KFP04975.1 - 0.017 15.3 0.0 0.54 10.5 0.0 2.1 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 Izumo-Ig PF16706.5 KFP04975.1 - 0.022 14.8 0.1 1.3 9.2 0.0 2.5 2 1 0 2 2 2 0 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFP04975.1 - 0.035 13.7 0.0 8.7 6.0 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin domain Mlf1IP PF10248.9 KFP04977.1 - 1.5e-60 204.1 4.5 1.8e-60 203.8 4.5 1.1 1 0 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein CSN7a_helixI PF18392.1 KFP04978.1 - 3.7e-21 74.7 2.5 6.2e-21 74.0 2.5 1.4 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain PCI PF01399.27 KFP04978.1 - 1.6e-07 31.8 0.2 6.2e-07 29.9 0.1 1.9 2 1 0 2 2 2 1 PCI domain DUF4200 PF13863.6 KFP04978.1 - 0.015 15.7 1.5 0.036 14.5 1.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Ribosomal_S3_C PF00189.20 KFP04978.1 - 0.026 15.0 0.1 0.045 14.3 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S3, C-terminal domain Band_3_cyto PF07565.13 KFP04978.1 - 0.24 11.2 2.5 0.34 10.7 2.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain AJAP1_PANP_C PF15298.6 KFP04979.1 - 1.6e-08 35.0 0.3 2e-07 31.5 0.0 2.0 1 1 1 2 2 2 1 AJAP1/PANP C-terminus EphA2_TM PF14575.6 KFP04979.1 - 0.062 14.2 0.0 0.095 13.6 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.6 KFP04979.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) zf-C2H2 PF00096.26 KFP04980.1 - 1.1e-22 79.1 53.8 1.8e-05 24.9 3.2 7.5 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP04980.1 - 2.3e-22 78.3 51.0 1.3e-06 28.6 0.3 7.7 8 0 0 8 8 8 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP04980.1 - 3.4e-11 43.0 52.2 0.002 18.8 3.0 7.9 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP04980.1 - 0.0027 17.9 32.5 0.0087 16.3 0.6 6.4 5 1 1 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFP04980.1 - 0.0037 17.1 0.9 0.0037 17.1 0.9 4.6 5 0 0 5 5 4 1 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 KFP04980.1 - 0.012 15.4 1.7 0.012 15.4 1.7 6.9 9 0 0 9 9 9 0 C2H2-type zinc-finger domain zf-C2HE PF16278.5 KFP04980.1 - 0.018 15.5 22.7 0.1 13.1 2.4 4.1 3 1 1 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 KFP04980.1 - 0.11 13.0 39.3 0.26 11.7 2.4 6.8 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFP04980.1 - 0.42 10.4 15.6 2.9 7.7 0.1 4.8 4 0 0 4 4 4 0 zinc-finger C2H2-type TerY_C PF15616.6 KFP04980.1 - 1.9 8.6 11.1 0.82 9.8 0.9 3.1 3 0 0 3 3 3 0 TerY-C metal binding domain zf-Di19 PF05605.12 KFP04980.1 - 2.7 8.3 35.6 0.2 12.0 4.1 4.5 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 KFP04980.1 - 3.8 7.7 20.4 0.1 12.8 2.4 4.2 3 1 1 4 4 4 0 Zinc ribbon domain ING PF12998.7 KFP04981.1 - 6.2e-27 94.1 2.0 6.2e-27 94.1 2.0 1.9 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KFP04981.1 - 2.2e-06 27.5 7.6 4.2e-06 26.6 7.6 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KFP04981.1 - 0.006 16.1 1.1 0.01 15.3 1.1 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KFP04981.1 - 0.008 16.4 0.5 0.019 15.2 0.5 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain Spc7 PF08317.11 KFP04981.1 - 0.013 14.4 7.5 0.016 14.1 7.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein AP3D1 PF06375.11 KFP04981.1 - 0.014 15.6 5.7 0.017 15.3 5.7 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DUF1319 PF07028.11 KFP04981.1 - 0.13 12.5 1.0 0.62 10.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) SOGA PF11365.8 KFP04981.1 - 0.19 12.9 11.2 1.5 10.0 5.5 2.9 1 1 1 2 2 2 0 Protein SOGA ABC_tran_CTD PF16326.5 KFP04981.1 - 0.22 11.8 5.4 0.77 10.0 0.7 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain ORF6C PF10552.9 KFP04981.1 - 0.32 11.1 7.5 1 9.4 2.2 2.1 2 0 0 2 2 2 0 ORF6C domain DASH_Spc19 PF08287.11 KFP04981.1 - 7.6 6.4 15.7 1.5 8.7 8.8 2.0 1 1 0 2 2 2 0 Spc19 PBP_sp32 PF07222.12 KFP04982.1 - 5.5e-38 130.8 6.3 2.1e-36 125.6 0.2 2.4 2 0 0 2 2 2 2 Proacrosin binding protein sp32 Kazal_2 PF07648.15 KFP04982.1 - 0.002 18.2 1.0 0.002 18.2 1.0 4.1 3 1 0 3 3 3 1 Kazal-type serine protease inhibitor domain 7tm_1 PF00001.21 KFP04983.1 - 7.1e-48 163.2 23.4 8.4e-48 163.0 23.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF983 PF06170.12 KFP04983.1 - 0.069 13.6 0.4 0.069 13.6 0.4 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF983) GPR_Gpa2_C PF11970.8 KFP04983.1 - 0.71 10.0 7.3 0.61 10.2 0.6 3.4 2 1 1 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term CitMHS PF03600.16 KFP04983.1 - 8.7 5.4 8.6 0.17 11.1 1.0 1.9 2 0 0 2 2 2 0 Citrate transporter CHDCT2 PF08074.11 KFP04984.1 - 1.1e-87 292.6 0.4 3.4e-87 291.0 0.4 1.9 1 0 0 1 1 1 1 CHDCT2 (NUC038) domain DUF1086 PF06461.11 KFP04984.1 - 4.2e-62 208.1 0.0 1.3e-61 206.5 0.0 1.9 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) SNF2_N PF00176.23 KFP04984.1 - 1.2e-59 201.8 0.2 3.2e-59 200.4 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF1087 PF06465.13 KFP04984.1 - 1.9e-26 91.8 6.0 1.9e-26 91.8 6.0 2.8 3 0 0 3 3 2 1 Domain of Unknown Function (DUF1087) CHDNT PF08073.12 KFP04984.1 - 9.6e-26 89.5 0.2 2.6e-25 88.1 0.2 1.8 1 0 0 1 1 1 1 CHDNT (NUC034) domain Helicase_C PF00271.31 KFP04984.1 - 2e-22 79.6 0.0 4.4e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD PF00628.29 KFP04984.1 - 2.3e-21 75.4 27.7 1.4e-10 40.9 8.8 2.5 2 0 0 2 2 2 2 PHD-finger Chromo PF00385.24 KFP04984.1 - 6.5e-19 67.6 6.7 1.3e-12 47.4 1.2 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 KFP04984.1 - 7.3e-10 39.1 0.0 4.1e-09 36.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KFP04984.1 - 1.3e-05 24.5 0.0 1.3e-05 24.5 0.0 2.1 2 1 0 2 2 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD_2 PF13831.6 KFP04984.1 - 0.0081 15.7 11.6 0.22 11.1 2.7 2.6 2 0 0 2 2 2 2 PHD-finger Filament PF00038.21 KFP04985.1 - 1.4e-15 57.7 28.0 3.8e-10 39.8 3.6 2.8 3 0 0 3 3 3 2 Intermediate filament protein CENP-F_leu_zip PF10473.9 KFP04985.1 - 0.018 15.0 5.4 0.018 15.0 5.4 3.3 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HlyE PF06109.13 KFP04985.1 - 0.12 11.7 2.0 0.13 11.5 0.0 2.0 3 0 0 3 3 3 0 Haemolysin E (HlyE) T2SSF PF00482.23 KFP04985.1 - 0.17 11.8 0.3 0.4 10.6 0.3 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F PAPA-1 PF04795.12 KFP04985.1 - 0.55 11.1 0.1 0.55 11.1 0.1 3.3 3 1 1 4 4 4 0 PAPA-1-like conserved region Snapin_Pallidin PF14712.6 KFP04985.1 - 0.82 10.1 14.3 0.16 12.4 4.3 3.1 3 1 0 3 3 3 0 Snapin/Pallidin DUF883 PF05957.13 KFP04985.1 - 4.5 8.0 10.9 0.43 11.2 0.5 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) SOAR PF16533.5 KFP04985.1 - 9.5 6.3 10.4 0.85 9.6 0.5 2.7 3 0 0 3 3 3 0 STIM1 Orai1-activating region Gp_dh_C PF02800.20 KFP04986.1 - 7.5e-69 230.3 0.0 1.2e-68 229.6 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KFP04986.1 - 1.5e-34 118.4 0.1 4.2e-34 116.9 0.1 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain OstA PF03968.14 KFP04986.1 - 0.017 15.3 0.0 0.044 14.0 0.0 1.7 1 0 0 1 1 1 0 OstA-like protein MRP-L51 PF10244.9 KFP04987.1 - 2.6e-35 120.5 0.6 3e-35 120.3 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit DUF4817 PF16087.5 KFP04987.1 - 0.27 11.1 1.5 9.3 6.1 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) Synaptobrevin PF00957.21 KFP04988.1 - 2e-29 101.2 1.0 2.1e-29 101.1 1.0 1.0 1 0 0 1 1 1 1 Synaptobrevin Orf78 PF06024.12 KFP04988.1 - 0.011 16.0 0.1 0.012 15.9 0.1 1.1 1 0 0 1 1 1 0 Orf78 (ac78) MgtE PF01769.16 KFP04988.1 - 0.025 15.0 0.1 0.028 14.8 0.1 1.1 1 0 0 1 1 1 0 Divalent cation transporter PRIMA1 PF16101.5 KFP04988.1 - 0.03 14.4 0.3 0.038 14.0 0.3 1.1 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Ferlin_C PF16165.5 KFP04988.1 - 0.031 14.2 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 Ferlin C-terminus Duffy_binding PF05424.11 KFP04988.1 - 0.053 13.6 0.0 0.06 13.4 0.0 1.1 1 0 0 1 1 1 0 Duffy binding domain MCU PF04678.13 KFP04988.1 - 0.069 13.2 0.1 0.073 13.2 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter SNARE PF05739.19 KFP04988.1 - 1.4 9.0 8.3 0.5 10.4 5.6 1.7 2 0 0 2 2 2 0 SNARE domain Ank_2 PF12796.7 KFP04989.1 - 4.5e-37 126.5 4.7 3.6e-12 46.7 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP04989.1 - 4.9e-37 125.5 8.1 7.6e-08 32.5 0.4 6.5 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP04989.1 - 1.4e-32 111.6 3.0 3.1e-08 34.0 0.1 4.9 4 1 0 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KFP04989.1 - 2e-30 103.9 8.2 8.6e-05 22.8 0.1 6.9 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 KFP04989.1 - 2.2e-30 101.3 1.6 5.3e-05 23.3 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat SAM_1 PF00536.30 KFP04989.1 - 4.7e-26 91.0 0.0 3e-15 56.4 0.0 2.8 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP04989.1 - 6.1e-22 77.5 1.6 1e-14 54.3 0.1 2.8 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) PID PF00640.23 KFP04990.1 - 1.2e-21 77.2 0.3 1.5e-21 76.9 0.3 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Coq4 PF05019.13 KFP04990.1 - 7.5e-05 22.2 0.1 0.00039 19.8 0.1 1.9 1 1 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 PTB PF08416.13 KFP04990.1 - 0.0031 17.7 0.1 0.0087 16.2 0.1 1.7 1 1 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.6 KFP04990.1 - 0.033 14.1 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) WD40 PF00400.32 KFP04991.1 - 1.1e-58 193.8 43.8 4.1e-09 36.9 0.0 13.3 13 0 0 13 13 13 10 WD domain, G-beta repeat NB-ARC PF00931.22 KFP04991.1 - 2.3e-57 194.1 0.7 3.6e-57 193.5 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain APAF1_C PF17908.1 KFP04991.1 - 3.5e-54 182.4 0.5 9.1e-54 181.1 0.5 1.8 1 0 0 1 1 1 1 APAF-1 helical domain ANAPC4_WD40 PF12894.7 KFP04991.1 - 6e-24 84.2 13.0 0.00085 19.6 0.1 9.9 2 2 7 10 10 10 8 Anaphase-promoting complex subunit 4 WD40 domain CARD PF00619.21 KFP04991.1 - 4.2e-17 61.9 1.0 1.5e-16 60.1 1.0 2.1 1 0 0 1 1 1 1 Caspase recruitment domain Ge1_WD40 PF16529.5 KFP04991.1 - 1.6e-11 43.8 8.6 0.0059 15.6 1.2 7.5 4 3 3 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein CARD_2 PF16739.5 KFP04991.1 - 6.5e-10 38.9 0.3 2e-09 37.3 0.3 1.9 1 0 0 1 1 1 1 Caspase recruitment domain WD40_like PF17005.5 KFP04991.1 - 1.7e-09 37.5 6.4 0.19 11.0 0.1 6.2 3 2 3 6 6 6 3 WD40-like domain eIF2A PF08662.11 KFP04991.1 - 1.5e-08 34.7 8.1 0.0023 17.9 0.1 4.8 3 1 2 5 5 5 2 Eukaryotic translation initiation factor eIF2A AAA_16 PF13191.6 KFP04991.1 - 0.00083 19.8 0.0 0.0018 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFP04991.1 - 0.014 15.7 0.0 0.17 12.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF2415 PF10313.9 KFP04991.1 - 0.081 12.9 0.5 0.96 9.4 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) DUF4795 PF16043.5 KFP04992.1 - 0.0013 18.4 9.2 0.0013 18.4 9.2 2.7 1 1 2 3 3 3 1 Domain of unknown function (DUF4795) MHC2-interact PF09307.10 KFP04992.1 - 0.0045 17.0 0.0 0.02 14.8 0.0 2.1 1 0 0 1 1 1 1 CLIP, MHC2 interacting CAMP_factor PF07373.11 KFP04992.1 - 0.0059 16.2 11.1 0.0081 15.8 7.2 2.3 2 1 0 2 2 2 1 CAMP factor (Cfa) DUF148 PF02520.17 KFP04992.1 - 0.012 15.8 2.3 0.012 15.8 2.3 3.2 2 1 1 3 3 3 0 Domain of unknown function DUF148 COG5 PF10392.9 KFP04992.1 - 0.035 14.3 13.5 0.86 9.8 3.9 3.6 1 1 2 3 3 3 0 Golgi transport complex subunit 5 Snapin_Pallidin PF14712.6 KFP04992.1 - 0.13 12.7 17.6 0.072 13.5 1.4 4.6 3 1 0 4 4 4 0 Snapin/Pallidin PvlArgDC PF01862.16 KFP04992.1 - 0.13 12.1 0.6 0.24 11.2 0.6 1.5 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) NPV_P10 PF05531.12 KFP04992.1 - 0.18 12.3 16.3 1.2 9.7 5.4 4.2 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF641 PF04859.12 KFP04992.1 - 3.5 8.0 8.6 5.4 7.4 0.3 3.5 2 2 1 3 3 3 0 Plant protein of unknown function (DUF641) DUF948 PF06103.11 KFP04992.1 - 3.5 7.9 14.3 6.5 7.1 3.4 4.1 1 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 KFP04992.1 - 4.2 7.6 18.8 0.9 9.7 3.5 4.0 1 1 4 5 5 5 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.12 KFP04992.1 - 4.7 7.3 15.9 1.8 8.6 1.3 3.7 2 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.22 KFP04992.1 - 9.4 6.5 16.5 1.4 9.2 0.5 3.9 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Aida_N PF08910.10 KFP04992.1 - 9.8 6.6 9.3 1.7 9.1 1.1 3.3 1 1 1 3 3 3 0 Aida N-terminus Mito_carr PF00153.27 KFP04993.1 - 1.1e-45 153.5 8.7 5.5e-19 67.9 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein LEM PF03020.15 KFP04994.1 - 2e-20 72.1 0.5 4e-20 71.1 0.5 1.6 1 0 0 1 1 1 1 LEM domain A1_Propeptide PF07966.12 KFP04995.1 - 0.065 13.1 0.2 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 A1 Propeptide Pkinase PF00069.25 KFP04996.1 - 1.5e-72 244.2 0.0 2.8e-72 243.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP04996.1 - 5.3e-35 120.9 0.0 1.1e-34 119.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFP04996.1 - 5e-07 29.0 0.1 2.4e-06 26.8 0.1 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFP04996.1 - 3.2e-06 26.7 0.0 7.7e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFP04996.1 - 0.00028 20.3 0.3 0.00072 19.0 0.3 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KFP04996.1 - 0.056 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KFP04996.1 - 0.07 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFP04996.1 - 0.12 11.1 0.2 3 6.5 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase Ets PF00178.22 KFP04997.1 - 1.8e-34 118.0 3.0 3.2e-34 117.2 3.0 1.4 1 0 0 1 1 1 1 Ets-domain Translat_reg PF01818.17 KFP04997.1 - 0.048 13.7 0.0 0.13 12.2 0.0 1.7 1 1 0 1 1 1 0 Bacteriophage translational regulator TPK_catalytic PF04263.16 KFP04999.1 - 4e-41 139.8 0.0 4.5e-41 139.6 0.0 1.0 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain Peptidase_C15 PF01470.17 KFP04999.1 - 0.056 13.6 0.0 0.073 13.2 0.0 1.1 1 0 0 1 1 1 0 Pyroglutamyl peptidase Abhydrolase_1 PF00561.20 KFP05001.1 - 7.9e-24 84.7 0.1 4.1e-18 65.9 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFP05001.1 - 8.9e-17 61.1 0.7 2e-15 56.8 0.7 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFP05001.1 - 5.2e-15 56.7 0.0 1.1e-14 55.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KFP05001.1 - 0.00017 21.5 0.3 0.52 10.1 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase DUF2920 PF11144.8 KFP05001.1 - 0.0061 15.8 0.0 0.23 10.6 0.0 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2920) UBA_6 PF18039.1 KFP05001.1 - 0.011 15.7 0.2 0.039 13.9 0.1 2.0 2 0 0 2 2 2 0 UBA-like domain FSH1 PF03959.13 KFP05001.1 - 0.013 15.1 0.0 0.035 13.8 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KFP05001.1 - 0.023 14.2 0.1 0.19 11.2 0.0 2.2 2 1 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.18 KFP05001.1 - 0.041 13.4 0.0 8.2 5.9 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_4 PF08386.10 KFP05001.1 - 0.042 14.0 0.0 0.093 12.8 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Ndr PF03096.14 KFP05001.1 - 0.075 11.7 0.1 0.48 9.1 0.1 2.0 1 1 0 1 1 1 0 Ndr family Ser_hydrolase PF06821.13 KFP05001.1 - 0.089 12.6 0.0 13 5.6 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase BAAT_C PF08840.11 KFP05001.1 - 0.13 12.2 0.0 1 9.2 0.0 2.3 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal LIP PF03583.14 KFP05001.1 - 0.16 11.3 0.0 0.44 9.8 0.0 1.7 1 1 1 2 2 2 0 Secretory lipase Abhydrolase_8 PF06259.12 KFP05001.1 - 0.19 11.3 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase VirJ PF06057.11 KFP05001.1 - 0.21 11.5 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Hormone_recep PF00104.30 KFP05002.1 - 5.7e-39 133.8 0.0 7.2e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor RTC PF01137.21 KFP05003.1 - 0.1 11.8 0.0 0.11 11.7 0.0 1.0 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase CaMBD PF02888.16 KFP05004.1 - 5e-24 84.3 5.6 8.4e-24 83.6 5.6 1.4 1 0 0 1 1 1 1 Calmodulin binding domain SK_channel PF03530.14 KFP05004.1 - 1.9e-15 56.9 0.7 2.8e-14 53.1 0.0 2.4 2 0 0 2 2 2 1 Calcium-activated SK potassium channel Ccdc124 PF06244.12 KFP05005.1 - 1.4e-41 142.0 9.7 1.4e-41 142.0 9.7 2.4 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 KFP05005.1 - 0.0038 17.6 0.8 0.0038 17.6 0.8 2.9 3 1 1 4 4 4 1 HMG (high mobility group) box UPF0240 PF06784.11 KFP05005.1 - 0.083 12.9 12.3 0.019 15.0 9.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) TMEM214 PF10151.9 KFP05005.1 - 6.5 5.1 12.1 10 4.5 12.1 1.4 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator SSF PF00474.17 KFP05006.1 - 1.5e-24 86.6 14.7 1.1e-12 47.6 6.3 2.1 1 1 1 2 2 2 2 Sodium:solute symporter family Lactamase_B_6 PF16661.5 KFP05007.1 - 0.18 11.2 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Ribosomal_L7Ae PF01248.26 KFP05008.1 - 6.8e-09 35.4 0.0 9.2e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family G-gamma PF00631.22 KFP05009.1 - 7.4e-19 67.5 0.0 8e-19 67.4 0.0 1.0 1 0 0 1 1 1 1 GGL domain FtsX_ECD PF18075.1 KFP05009.1 - 0.0048 17.5 0.0 0.0053 17.3 0.0 1.0 1 0 0 1 1 1 1 FtsX extracellular domain CP12 PF02672.15 KFP05009.1 - 0.021 15.6 0.1 0.027 15.2 0.1 1.2 1 0 0 1 1 1 0 CP12 domain Zip PF02535.22 KFP05010.1 - 3.7e-48 164.5 13.6 3.7e-47 161.2 13.6 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter DUF1129 PF06570.11 KFP05010.1 - 0.56 9.7 3.2 0.58 9.6 1.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) TPR_1 PF00515.28 KFP05011.1 - 1.5e-27 94.2 5.8 3.2e-10 39.4 0.0 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat SGTA_dimer PF16546.5 KFP05011.1 - 1.7e-22 78.9 1.0 4.2e-22 77.7 0.1 2.0 2 0 0 2 2 2 1 Homodimerisation domain of SGTA TPR_2 PF07719.17 KFP05011.1 - 5.7e-20 69.8 4.5 4.6e-06 26.3 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFP05011.1 - 9.6e-20 69.1 3.3 1.9e-07 30.7 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFP05011.1 - 6.6e-17 60.9 6.3 9.2e-07 28.4 0.3 4.1 2 1 2 4 4 4 3 TPR repeat TPR_17 PF13431.6 KFP05011.1 - 8e-14 50.9 3.5 6.7e-06 26.1 0.3 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFP05011.1 - 3.2e-12 45.6 0.2 0.00082 19.2 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP05011.1 - 3.7e-10 39.7 0.0 0.014 16.1 0.0 4.3 3 1 2 5 5 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFP05011.1 - 7.1e-10 39.4 1.4 1.4e-05 25.7 0.1 2.8 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFP05011.1 - 7.3e-09 35.8 2.2 4.3e-07 30.1 0.2 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP05011.1 - 1.1e-08 35.4 0.4 9.6e-06 26.0 0.0 3.3 3 1 1 4 4 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFP05011.1 - 3.4e-08 33.1 3.8 0.0084 15.9 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFP05011.1 - 7.7e-05 22.8 0.1 0.0028 17.8 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TOM20_plant PF06552.12 KFP05011.1 - 9e-05 22.3 1.6 0.3 10.8 0.1 3.0 3 1 0 3 3 3 2 Plant specific mitochondrial import receptor subunit TOM20 TPR_6 PF13174.6 KFP05011.1 - 0.00011 22.6 0.7 1.1 10.1 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFP05011.1 - 0.00014 21.8 5.0 0.048 13.7 0.1 3.2 3 1 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 KFP05011.1 - 0.0019 18.6 1.7 0.33 11.4 0.1 2.9 2 1 1 3 3 3 1 Bacterial transcriptional activator domain NARP1 PF12569.8 KFP05011.1 - 0.0023 16.9 0.4 1.1 8.0 0.3 2.2 1 1 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 KFP05011.1 - 0.0047 16.2 0.0 1.6 7.8 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat DUF627 PF04781.12 KFP05011.1 - 0.008 16.2 0.2 0.31 11.1 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF627) MIT PF04212.18 KFP05011.1 - 0.11 12.6 7.1 9.7 6.4 0.1 4.2 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain DUF3856 PF12968.7 KFP05011.1 - 0.11 12.5 1.1 8.2 6.5 1.1 3.1 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) TrbI PF03743.14 KFP05011.1 - 0.2 11.5 2.8 0.31 10.8 2.7 1.5 1 1 0 1 1 1 0 Bacterial conjugation TrbI-like protein XPC-binding PF09280.11 KFP05011.1 - 0.44 10.3 9.9 3.1 7.6 4.0 2.7 2 0 0 2 2 2 0 XPC-binding domain STI1 PF17830.1 KFP05011.1 - 0.65 10.0 5.6 0.33 10.9 0.6 2.5 2 0 0 2 2 2 0 STI1 domain Peptidase_M3 PF01432.20 KFP05012.1 - 4.3e-165 550.4 0.0 5.5e-165 550.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 DUF4085 PF13315.6 KFP05012.1 - 0.048 13.3 0.3 0.13 11.8 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4085) CdvA PF18822.1 KFP05012.1 - 0.13 12.1 3.7 0.073 12.9 0.9 1.9 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Peptidase_S8 PF00082.22 KFP05013.1 - 2.4e-33 115.7 0.3 3.5e-33 115.2 0.3 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KFP05013.1 - 4e-27 94.1 0.1 6.9e-27 93.3 0.1 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KFP05013.1 - 2.7e-21 76.1 0.4 5.8e-21 75.1 0.4 1.6 1 0 0 1 1 1 1 Peptidase S8 pro-domain Furin-like_2 PF15913.5 KFP05013.1 - 0.033 14.3 0.9 0.033 14.3 0.9 2.5 1 1 1 2 2 2 0 Furin-like repeat, cysteine-rich Imm32 PF15566.6 KFP05013.1 - 0.14 12.0 0.5 4 7.3 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 32 TB2_DP1_HVA22 PF03134.19 KFP05014.1 - 1.3e-24 85.9 2.4 1.5e-24 85.7 2.4 1.0 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Ribosomal_S19 PF00203.21 KFP05015.1 - 2.4e-25 88.2 0.1 2.7e-25 88.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19 DUF3619 PF12279.8 KFP05015.1 - 0.089 13.1 0.1 0.094 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) RRM_1 PF00076.22 KFP05016.1 - 2e-36 123.7 0.2 8.8e-18 63.9 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP05016.1 - 9.9e-13 48.0 0.3 2.3e-07 30.8 0.1 2.5 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KFP05016.1 - 1.5e-05 24.9 0.2 0.062 13.3 0.1 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KFP05016.1 - 0.00045 20.5 0.0 0.54 10.5 0.0 2.8 2 1 1 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter CSD PF00313.22 KFP05016.1 - 0.029 14.2 1.1 1.5 8.8 0.1 2.3 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain Oxidored_q6 PF01058.22 KFP05018.1 - 7.3e-06 25.8 0.0 0.043 13.6 0.0 2.1 2 0 0 2 2 2 2 NADH ubiquinone oxidoreductase, 20 Kd subunit Pkinase PF00069.25 KFP05019.1 - 7e-48 163.3 0.0 1.8e-30 106.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFP05019.1 - 1.9e-11 43.8 0.0 3.2e-05 23.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Ephrin PF00812.17 KFP05020.1 - 2.1e-34 118.5 0.1 2.3e-34 118.3 0.1 1.0 1 0 0 1 1 1 1 Ephrin DUF1180 PF06679.12 KFP05021.1 - 8.9e-15 55.5 5.9 8.7e-13 49.0 0.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1180) RRM_1 PF00076.22 KFP05022.1 - 4.6e-26 90.4 0.1 7.3e-26 89.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP05022.1 - 0.00015 21.8 0.1 0.00029 20.9 0.1 1.5 1 1 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 KFP05022.1 - 0.00043 20.1 0.0 0.00088 19.1 0.0 1.4 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KFP05022.1 - 0.077 13.0 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 RNA binding motif RRM_5 PF13893.6 KFP05022.1 - 0.083 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KFP05022.1 - 0.26 11.5 0.0 0.34 11.1 0.0 1.2 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter API5 PF05918.11 KFP05022.1 - 0.37 9.5 2.2 0.49 9.1 2.2 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF3540 PF12059.8 KFP05023.1 - 0.047 13.5 2.6 0.057 13.3 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3540) Pkinase PF00069.25 KFP05024.1 - 8e-57 192.6 0.0 9.8e-57 192.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP05024.1 - 5e-34 117.8 0.0 7.2e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP05024.1 - 1.1e-11 44.6 0.0 2.3e-11 43.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP05024.1 - 0.0035 16.2 0.0 0.012 14.4 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KFP05024.1 - 0.0051 16.2 0.1 0.012 15.0 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP05024.1 - 0.081 12.8 0.0 0.77 9.6 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family RNA_pol_Rpb5_C PF01191.19 KFP05025.1 - 4.1e-35 119.5 0.5 1e-34 118.2 0.2 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KFP05025.1 - 6.9e-35 119.5 0.0 1.2e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain FumaraseC_C PF10415.9 KFP05025.1 - 0.1 13.0 0.8 4.6 7.8 0.0 2.5 2 0 0 2 2 2 0 Fumarase C C-terminus Calponin PF00402.18 KFP05026.1 - 1.1e-40 136.9 30.9 2.2e-16 59.1 1.6 4.7 5 0 0 5 5 5 3 Calponin family repeat CH PF00307.31 KFP05026.1 - 3.7e-23 81.8 0.1 6.3e-23 81.0 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFP05026.1 - 0.0012 18.7 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain CDC24 PF06395.11 KFP05026.1 - 0.16 12.3 0.1 0.28 11.5 0.1 1.3 1 0 0 1 1 1 0 CDC24 Calponin Membralin PF09746.9 KFP05027.1 - 4.7e-174 578.9 6.0 7.9e-174 578.1 6.0 1.3 1 0 0 1 1 1 1 Tumour-associated protein WD40 PF00400.32 KFP05029.1 - 4.2e-23 81.2 5.1 9.6e-10 38.9 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat WD40_alt PF14077.6 KFP05029.1 - 3.2e-20 71.7 0.5 5.3e-20 71.0 0.5 1.4 1 0 0 1 1 1 1 Alternative WD40 repeat motif ANAPC4_WD40 PF12894.7 KFP05029.1 - 4.8e-06 26.8 0.0 0.00067 19.9 0.0 2.6 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP05029.1 - 0.0014 17.3 0.5 0.013 14.2 0.4 2.0 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFP05029.1 - 0.15 11.0 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Med16 PF11635.8 KFP05030.1 - 2.7e-136 455.5 0.2 3.4e-136 455.1 0.2 1.1 1 0 0 1 1 1 1 Mediator complex subunit 16 WD40 PF00400.32 KFP05030.1 - 0.00013 22.7 5.4 0.00026 21.7 1.9 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP05030.1 - 0.00027 21.2 0.3 0.062 13.6 0.2 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PAP2 PF01569.21 KFP05031.1 - 6.1e-14 51.9 4.5 1.1e-13 51.1 4.5 1.3 1 0 0 1 1 1 1 PAP2 superfamily RRM_5 PF13893.6 KFP05032.1 - 5.3e-57 190.8 1.1 1.9e-39 134.1 0.0 4.1 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KFP05032.1 - 2.1e-35 120.4 0.2 6.2e-09 35.6 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KFP05032.1 - 1.8e-14 53.7 0.0 1.8e-13 50.5 0.0 2.2 2 0 0 2 2 2 1 RRM-like domain RRM_occluded PF16842.5 KFP05032.1 - 5.2e-11 42.3 0.8 0.25 11.2 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif AKAP2_C PF15304.6 KFP05033.1 - 4.2e-36 125.0 21.0 4.2e-36 125.0 21.0 4.3 4 1 0 4 4 4 2 A-kinase anchor protein 2 C-terminus Trypsin PF00089.26 KFP05034.1 - 2.3e-51 174.7 0.0 3e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFP05034.1 - 0.0001 22.6 0.0 0.00017 22.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 KFP05034.1 - 0.0096 16.8 0.1 0.19 12.6 0.1 2.2 1 1 0 1 1 1 1 Trypsin-like peptidase domain zf-RING_2 PF13639.6 KFP05035.1 - 1.2e-13 51.2 6.5 1.2e-13 51.2 6.5 1.6 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP05035.1 - 5.3e-09 35.8 6.4 5.3e-09 35.8 6.4 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFP05035.1 - 1.8e-08 34.0 1.2 1.8e-08 34.0 1.2 1.8 2 0 0 2 2 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KFP05035.1 - 2.1e-08 34.3 4.9 2.1e-08 34.3 4.9 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFP05035.1 - 2.8e-07 30.4 4.5 3.7e-07 30.1 2.3 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFP05035.1 - 4.4e-07 29.7 5.6 4.4e-07 29.7 5.6 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP05035.1 - 1.8e-06 27.7 2.4 1.8e-06 27.7 2.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP05035.1 - 3.8e-06 26.7 4.9 3.8e-06 26.7 4.9 1.9 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP05035.1 - 7.5e-05 22.5 7.6 7.5e-05 22.5 7.6 2.5 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFP05035.1 - 8.7e-05 22.5 3.5 0.00024 21.1 3.5 1.7 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_9 PF14369.6 KFP05035.1 - 0.0035 17.6 6.2 0.006 16.8 0.5 3.1 3 0 0 3 3 3 1 zinc-ribbon zf-Nse PF11789.8 KFP05035.1 - 0.0059 16.4 2.9 0.012 15.4 2.9 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Vps39_2 PF10367.9 KFP05035.1 - 0.0098 16.3 0.9 2.2 8.8 0.4 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Zn_ribbon_17 PF17120.5 KFP05035.1 - 0.029 14.0 3.8 0.029 14.0 3.8 1.6 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type Rad50_zn_hook PF04423.14 KFP05035.1 - 0.089 12.7 4.9 0.53 10.2 0.0 3.0 3 0 0 3 3 3 0 Rad50 zinc hook motif DUF983 PF06170.12 KFP05035.1 - 0.099 13.1 0.1 4.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF983) zf-RING_4 PF14570.6 KFP05035.1 - 0.099 12.5 6.0 4.7 7.1 0.0 2.9 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Opy2 PF09463.10 KFP05035.1 - 0.47 10.8 4.3 33 4.9 0.1 3.2 3 0 0 3 3 3 0 Opy2 protein zf-H2C2_2 PF13465.6 KFP05035.1 - 1.5 9.4 3.8 37 5.0 0.1 3.0 3 0 0 3 3 2 0 Zinc-finger double domain PHD PF00628.29 KFP05035.1 - 2.5 8.1 9.4 2.9 7.8 4.9 2.5 2 0 0 2 2 2 0 PHD-finger FANCL_C PF11793.8 KFP05035.1 - 3.3 7.9 7.7 60 3.9 7.8 2.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KFP05035.1 - 9.1 6.7 12.3 0.092 13.1 4.8 1.6 2 0 0 2 2 1 0 RING-like domain FGF PF00167.18 KFP05036.1 - 5.3e-34 117.0 0.0 5.8e-34 116.9 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor RNA_pol PF00940.19 KFP05038.1 - 1.8e-164 547.5 0.0 2.3e-164 547.2 0.0 1.1 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KFP05038.1 - 7.2e-55 186.7 0.0 1.2e-54 186.0 0.0 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Rx_N PF18052.1 KFP05038.1 - 0.064 13.5 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 Rx N-terminal domain Ion_trans PF00520.31 KFP05039.1 - 2.1e-22 79.6 16.5 3.2e-22 79.0 16.5 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KFP05039.1 - 1.4e-18 66.7 0.0 2.9e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KFP05039.1 - 0.0015 18.5 0.2 0.0064 16.4 0.2 2.1 2 0 0 2 2 2 1 Ion channel Ig_3 PF13927.6 KFP05040.1 - 1.7e-16 60.6 9.5 4.1e-12 46.5 0.5 3.6 3 1 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFP05040.1 - 1.6e-12 47.6 5.3 6.2e-08 32.9 0.5 3.4 2 1 1 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFP05040.1 - 1.9e-12 47.1 0.9 9.7e-09 35.2 0.0 3.4 3 1 1 4 4 4 2 Immunoglobulin I-set domain V-set PF07686.17 KFP05040.1 - 2.2e-09 37.5 2.4 0.00069 19.8 0.3 4.2 3 2 0 3 3 3 3 Immunoglobulin V-set domain ig PF00047.25 KFP05040.1 - 3.4e-06 27.1 3.7 0.0082 16.3 0.2 3.8 3 2 0 3 3 3 1 Immunoglobulin domain Ig_6 PF18452.1 KFP05040.1 - 0.0023 17.4 0.1 4.6 6.9 0.0 3.6 3 0 0 3 3 3 2 Immunoglobulin domain Ig_4 PF16680.5 KFP05040.1 - 0.0024 18.1 1.7 18 5.7 0.0 3.6 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFP05040.1 - 0.005 17.2 0.9 6.1 7.3 0.0 3.5 3 1 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Orthoreo_P10 PF07204.11 KFP05040.1 - 0.024 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 C2-set PF05790.15 KFP05040.1 - 0.15 12.2 0.0 2.7 8.3 0.0 3.0 4 0 0 4 4 4 0 Immunoglobulin C2-set domain UQ_con PF00179.26 KFP05041.1 - 2.8e-43 146.9 0.0 3.7e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFP05041.1 - 0.024 14.3 0.0 0.075 12.7 0.0 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B MFS_1 PF07690.16 KFP05042.1 - 5.8e-34 117.5 37.9 2.1e-33 115.7 37.7 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KFP05042.1 - 2.4e-11 43.1 24.5 3.2e-08 32.8 24.5 3.2 1 1 0 1 1 1 1 MFS_1 like family PID PF00640.23 KFP05043.1 - 1.9e-30 105.7 0.0 2.6e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) C2 PF00168.30 KFP05044.1 - 2.4e-10 40.6 0.0 4.2e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain ELM2 PF01448.24 KFP05045.1 - 2.9e-11 43.9 1.6 5.2e-11 43.1 0.1 2.3 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-binding PF00249.31 KFP05045.1 - 3.7e-07 30.2 0.6 1.1e-06 28.7 0.6 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2002 PF09400.10 KFP05045.1 - 0.047 13.7 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2002) PAP2 PF01569.21 KFP05046.1 - 1.1e-26 93.2 1.6 1.1e-26 93.2 1.6 1.5 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KFP05046.1 - 0.0061 17.1 2.4 0.0061 17.1 2.4 2.3 2 1 0 2 2 2 1 PAP2 superfamily C-terminal DUF2976 PF11190.8 KFP05046.1 - 0.4 10.5 2.1 0.52 10.1 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Cytochrom_B561 PF03188.16 KFP05046.1 - 0.61 10.2 5.2 1.1 9.4 0.6 2.4 1 1 0 2 2 2 0 Eukaryotic cytochrome b561 PAP2_3 PF14378.6 KFP05046.1 - 1.7 8.3 7.8 1 9.0 4.4 2.2 2 1 0 2 2 2 0 PAP2 superfamily TLE_N PF03920.15 KFP05047.1 - 3.4e-65 218.0 10.9 4.5e-65 217.6 10.9 1.2 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain HEPN_STY4199 PF18729.1 KFP05047.1 - 0.017 14.4 1.3 0.024 13.9 1.0 1.3 1 1 0 1 1 1 0 STY4199-like HEPN HALZ PF02183.18 KFP05047.1 - 0.035 14.3 0.2 0.079 13.2 0.2 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper TLE_N PF03920.15 KFP05048.1 - 8.4e-69 229.7 7.3 1e-68 229.4 7.3 1.1 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain HALZ PF02183.18 KFP05048.1 - 0.002 18.3 0.9 0.0052 17.0 0.9 1.7 1 0 0 1 1 1 1 Homeobox associated leucine zipper FliG_N PF14842.6 KFP05048.1 - 0.014 15.9 0.6 0.025 15.1 0.3 1.6 2 0 0 2 2 2 0 FliG N-terminal domain G-alpha PF00503.20 KFP05049.1 - 1.3e-108 363.4 2.0 1.5e-108 363.2 2.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFP05049.1 - 4.4e-12 45.8 0.2 2.7e-11 43.2 0.2 2.2 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP05049.1 - 0.14 12.2 0.1 2 8.5 0.1 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase Trypsin PF00089.26 KFP05050.1 - 2.2e-24 86.5 0.0 5.5e-17 62.3 0.0 2.0 1 1 1 2 2 2 2 Trypsin DUF1986 PF09342.11 KFP05050.1 - 0.031 14.7 0.0 0.04 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Trypsin PF00089.26 KFP05051.1 - 3.4e-60 203.6 0.0 3.8e-60 203.4 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFP05051.1 - 0.0004 21.3 0.0 0.00087 20.2 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_M28 PF04389.17 KFP05052.1 - 4.7e-12 46.0 0.0 9.3e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.15 KFP05052.1 - 8.9e-07 28.6 0.0 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Nicastrin RRM_1 PF00076.22 KFP05053.1 - 1.1e-37 127.7 0.0 5.2e-17 61.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFP05053.1 - 0.0071 16.3 0.0 1.6 8.8 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KFP05053.1 - 0.14 12.4 0.2 18 5.5 0.0 2.5 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Peripla_BP_4 PF13407.6 KFP05053.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein domain QIL1 PF15884.5 KFP05054.1 - 2.2e-24 85.8 0.0 2.6e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 MICOS complex subunit MIC13, QIL1 ABC_sub_bind PF04392.12 KFP05054.1 - 0.15 11.2 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 ABC transporter substrate binding protein CAF1-p150_C2 PF15539.6 KFP05055.1 - 4e-117 390.8 1.3 1.4e-116 389.0 1.3 2.0 1 0 0 1 1 1 1 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term CAF-1_p150 PF11600.8 KFP05055.1 - 6.2e-65 217.9 67.9 1.9e-64 216.3 67.9 1.9 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal CAF1-p150_N PF15557.6 KFP05055.1 - 6.3e-40 137.5 7.9 6.3e-40 137.5 7.9 2.4 2 0 0 2 2 2 1 CAF1 complex subunit p150, region binding to PCNA CAF1A PF12253.8 KFP05055.1 - 3.4e-26 91.2 9.5 3.4e-26 91.2 9.5 5.3 4 1 0 4 4 4 1 Chromatin assembly factor 1 subunit A DUF262 PF03235.14 KFP05055.1 - 5.2 7.2 10.2 14 5.8 10.2 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF262 PUB PF09409.10 KFP05056.1 - 3.9e-25 87.6 0.2 9.3e-25 86.4 0.1 1.7 2 0 0 2 2 2 1 PUB domain UBX PF00789.20 KFP05056.1 - 2e-08 34.3 0.0 4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 UBX domain LEDGF PF11467.8 KFP05057.1 - 4.7e-27 94.0 1.3 1.2e-26 92.7 1.3 1.7 1 0 0 1 1 1 1 Lens epithelium-derived growth factor (LEDGF) PWWP PF00855.17 KFP05057.1 - 0.0032 17.8 4.5 0.0032 17.8 0.0 2.8 3 0 0 3 3 3 1 PWWP domain Pex14_N PF04695.13 KFP05057.1 - 0.069 13.8 0.0 0.069 13.8 0.0 3.7 2 1 2 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MAT1 PF06391.13 KFP05057.1 - 0.72 9.6 21.1 1.4 8.7 12.8 2.7 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Perilipin PF03036.16 KFP05058.1 - 1.9e-155 517.8 25.5 1.8e-154 514.5 25.5 1.9 1 1 0 1 1 1 1 Perilipin family Prefoldin_3 PF13758.6 KFP05058.1 - 0.0036 17.3 0.4 0.01 15.9 0.4 1.8 1 0 0 1 1 1 1 Prefoldin subunit DUF2218 PF09981.9 KFP05058.1 - 0.014 15.8 0.1 0.4 11.1 0.1 2.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2218) DUF445 PF04286.12 KFP05058.1 - 0.12 12.1 0.7 0.36 10.6 0.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Spc7 PF08317.11 KFP05058.1 - 0.4 9.5 6.8 0.42 9.4 1.3 2.4 3 0 0 3 3 3 0 Spc7 kinetochore protein ApoLp-III PF07464.11 KFP05058.1 - 0.77 9.8 12.0 0.94 9.6 0.2 3.7 3 2 1 4 4 4 0 Apolipophorin-III precursor (apoLp-III) DUF1664 PF07889.12 KFP05058.1 - 2.1 8.4 8.7 8 6.5 0.1 3.5 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 KFP05058.1 - 5.9 7.2 7.2 51 4.2 0.1 4.3 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Glypican PF01153.19 KFP05059.1 - 1.9e-111 373.7 1.6 2.1e-111 373.5 1.6 1.0 1 0 0 1 1 1 1 Glypican Fz PF01392.22 KFP05059.1 - 0.079 13.6 0.3 0.079 13.6 0.3 2.4 2 1 0 2 2 2 0 Fz domain CysA_C_terminal PF17850.1 KFP05060.1 - 0.12 12.9 5.2 1.2e+02 3.4 5.2 3.5 1 1 0 1 1 1 0 CysA C-terminal regulatory domain fn3 PF00041.21 KFP05061.1 - 8.3e-136 442.7 24.4 3.4e-16 59.4 0.1 9.3 9 0 0 9 9 9 9 Fibronectin type III domain Fibrinogen_C PF00147.18 KFP05061.1 - 1.3e-70 237.7 6.9 2.6e-70 236.7 6.9 1.5 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain EGF_2 PF07974.13 KFP05061.1 - 4.8e-18 65.2 88.6 0.00031 21.1 12.8 5.8 5 0 0 5 5 5 5 EGF-like domain EGF_Tenascin PF18720.1 KFP05061.1 - 1.9e-17 62.9 65.5 1.7e-06 27.9 4.4 5.6 5 0 0 5 5 5 4 Tenascin EGF domain Pur_ac_phosph_N PF16656.5 KFP05061.1 - 5.3e-14 52.6 20.8 0.002 18.7 0.2 10.2 8 6 0 8 8 8 3 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFP05061.1 - 3.9e-12 46.4 0.0 0.84 10.0 0.0 7.9 8 1 1 9 9 9 3 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 KFP05061.1 - 1.3e-08 35.1 0.1 0.43 11.0 0.0 6.4 6 0 0 6 6 6 1 Uncharacterised conserved protein (DUF2369) DUF4998 PF16389.5 KFP05061.1 - 9.2e-08 31.9 0.1 0.087 12.4 0.0 5.6 7 0 0 7 7 7 2 Domain of unknown function fn3_2 PF16893.5 KFP05061.1 - 1e-07 32.0 0.1 0.92 9.7 0.0 6.9 7 0 0 7 7 7 1 Fibronectin type III domain EGF PF00008.27 KFP05061.1 - 5.3e-06 26.6 83.7 0.00013 22.2 9.3 5.9 6 0 0 6 6 5 4 EGF-like domain DUF4959 PF16323.5 KFP05061.1 - 0.028 14.7 0.0 21 5.5 0.0 4.8 4 2 2 6 6 6 0 Domain of unknown function (DUF4959) DUF4945 PF16303.5 KFP05061.1 - 0.2 11.6 1.6 55 3.7 0.0 4.8 6 0 0 6 6 6 0 Domain of unknown function (DUF4945) hEGF PF12661.7 KFP05061.1 - 2.9 8.7 60.7 0.024 15.3 4.4 5.9 5 0 0 5 5 5 0 Human growth factor-like EGF TNF PF00229.18 KFP05062.1 - 6.4e-14 52.0 0.0 1.1e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family TNF PF00229.18 KFP05063.1 - 1.4e-35 122.0 0.1 2e-35 121.5 0.1 1.2 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family DUF4481 PF14800.6 KFP05064.1 - 5.2e-47 160.7 4.2 5.7e-47 160.6 4.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4481) CDP-OH_P_transf PF01066.21 KFP05064.1 - 0.12 13.2 0.2 0.21 12.4 0.2 1.3 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase V-ATPase_G PF03179.15 KFP05065.1 - 1e-24 87.1 6.6 1.1e-24 86.9 6.6 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit RRF PF01765.19 KFP05065.1 - 0.12 12.3 3.3 0.16 11.9 3.3 1.1 1 0 0 1 1 1 0 Ribosome recycling factor Con-6 PF10346.9 KFP05065.1 - 0.74 9.9 3.0 1.9 8.6 3.0 1.6 1 0 0 1 1 1 0 Conidiation protein 6 Sds3 PF08598.11 KFP05065.1 - 2 8.4 6.8 7.7 6.5 0.1 2.0 1 1 0 2 2 2 0 Sds3-like PDZ PF00595.24 KFP05066.1 - 2.9e-24 85.2 0.7 6.7e-15 55.2 0.1 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFP05066.1 - 3.8e-16 58.7 0.0 5.9e-08 32.4 0.0 3.0 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFP05066.1 - 1.1e-08 35.3 0.0 0.00016 21.9 0.0 3.2 2 1 1 3 3 3 2 PDZ domain Sec1 PF00995.23 KFP05067.1 - 3.7e-15 56.2 0.0 4.1e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.23 KFP05068.1 - 1.1e-103 348.4 5.3 1.3e-103 348.3 5.3 1.0 1 0 0 1 1 1 1 Sec1 family YlbD_coat PF14071.6 KFP05068.1 - 0.029 14.6 0.8 0.071 13.4 0.8 1.6 1 0 0 1 1 1 0 Putative coat protein DUF365 PF04033.12 KFP05068.1 - 0.11 12.7 0.2 1.7 9.0 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF365) Ctr PF04145.15 KFP05069.1 - 9.3e-19 68.5 7.0 2.7e-18 67.0 7.0 1.6 1 1 0 1 1 1 1 Ctr copper transporter family Ion_trans PF00520.31 KFP05070.1 - 1.6e-250 826.6 77.6 1.1e-65 221.3 25.7 4.1 4 0 0 4 4 4 4 Ion transport protein Ca_chan_IQ PF08763.11 KFP05070.1 - 1.9e-32 111.3 0.0 4.8e-32 110.0 0.0 1.8 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain GPHH PF16905.5 KFP05070.1 - 8e-31 105.6 0.2 3.1e-30 103.7 0.4 2.0 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 KFP05070.1 - 2.3e-08 33.1 85.6 4.4e-06 25.6 10.7 9.5 6 4 3 9 9 9 4 Polycystin cation channel Tmemb_9 PF05434.11 KFP05070.1 - 0.3 11.0 2.1 12 5.8 0.0 3.1 2 0 0 2 2 2 0 TMEM9 Ank_2 PF12796.7 KFP05071.1 - 5.3e-46 155.1 2.4 6.7e-16 58.6 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP05071.1 - 6.1e-42 141.5 4.9 8.6e-13 48.5 0.0 5.4 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP05071.1 - 8.9e-35 114.8 5.3 2e-05 24.6 0.0 7.7 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KFP05071.1 - 1.3e-34 117.8 8.9 5.1e-10 39.4 0.0 6.4 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KFP05071.1 - 8.1e-34 114.6 2.8 5.4e-05 23.5 0.0 7.0 7 0 0 7 7 7 6 Ankyrin repeat SET PF00856.28 KFP05071.1 - 2.6e-23 83.2 0.1 2.6e-23 83.2 0.1 3.8 3 1 0 3 3 3 1 SET domain Pre-SET PF05033.16 KFP05071.1 - 2.6e-16 60.2 13.2 2.6e-16 60.2 13.2 3.1 3 0 0 3 3 3 1 Pre-SET motif Arrestin_C PF02752.22 KFP05072.1 - 3.8e-23 82.4 0.1 2.9e-21 76.3 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KFP05072.1 - 7.1e-14 52.1 0.1 5e-13 49.4 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KFP05072.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Arrestin_N terminal like Gln-synt_C PF00120.24 KFP05073.1 - 6e-16 58.4 0.0 1.7e-11 43.8 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KFP05073.1 - 2e-12 46.7 0.0 3.5e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain COBRA1 PF06209.13 KFP05074.1 - 3.1e-251 834.2 3.0 3.7e-251 833.9 3.0 1.1 1 0 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) Nnf1 PF03980.14 KFP05074.1 - 0.72 10.3 3.5 0.56 10.6 0.8 2.1 2 0 0 2 2 2 0 Nnf1 GDA1_CD39 PF01150.17 KFP05075.1 - 3.6e-36 124.7 0.0 4.3e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Tubulin_C PF03953.17 KFP05076.1 - 1.6e-43 147.9 0.1 2.6e-43 147.2 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 KFP05076.1 - 2.6e-42 145.3 0.0 4.5e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 KFP05076.1 - 0.0052 16.5 0.0 0.0089 15.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KFP05076.1 - 0.011 15.0 0.1 0.025 13.8 0.0 1.6 2 0 0 2 2 2 0 Tubulin like DUF2475 PF10629.9 KFP05078.1 - 2.4e-08 34.0 0.6 9.8e-05 22.5 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2475) DUF2475 PF10629.9 KFP05079.1 - 3.7e-08 33.5 3.6 5.4e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2475) Pkinase_Tyr PF07714.17 KFP05080.1 - 1.2e-83 280.4 0.0 1.6e-83 280.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP05080.1 - 2.9e-41 141.6 0.0 2.1e-40 138.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain TMEM154 PF15102.6 KFP05080.1 - 0.00082 19.3 0.3 0.0014 18.6 0.3 1.3 1 0 0 1 1 1 1 TMEM154 protein family Mid2 PF04478.12 KFP05080.1 - 0.0053 16.6 0.4 0.01 15.7 0.4 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor F5_F8_type_C PF00754.25 KFP05080.1 - 0.0058 16.8 0.6 0.014 15.5 0.0 2.0 3 0 0 3 3 3 1 F5/8 type C domain DUF2062 PF09835.9 KFP05080.1 - 0.015 15.2 0.1 0.031 14.1 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Haspin_kinase PF12330.8 KFP05080.1 - 0.02 13.8 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF3377 PF11857.8 KFP05080.1 - 0.061 13.3 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) F5_F8_type_C PF00754.25 KFP05081.1 - 1.7e-12 47.5 0.0 2e-12 47.3 0.0 1.0 1 0 0 1 1 1 1 F5/8 type C domain Torsin PF06309.11 KFP05082.1 - 2.8e-14 53.3 0.0 7.7e-14 51.9 0.0 1.7 2 0 0 2 2 2 1 Torsin AAA_16 PF13191.6 KFP05082.1 - 1.4e-05 25.6 0.0 0.011 16.2 0.0 3.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KFP05082.1 - 0.00073 19.8 0.1 0.67 10.2 0.0 2.9 1 1 1 2 2 2 2 AAA domain AAA_18 PF13238.6 KFP05082.1 - 0.0086 16.6 0.0 0.033 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KFP05082.1 - 0.042 14.3 0.0 0.12 12.8 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cullin PF00888.22 KFP05083.1 - 8e-31 107.3 1.3 8e-31 107.3 1.3 2.1 2 0 0 2 2 2 1 Cullin family ANAPC2 PF08672.11 KFP05083.1 - 4e-24 84.9 1.3 2e-23 82.6 0.7 2.6 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 Cor1 PF04803.12 KFP05083.1 - 0.03 14.5 6.8 2.1 8.5 1.1 3.5 3 0 0 3 3 3 0 Cor1/Xlr/Xmr conserved region Phostensin PF13914.6 KFP05084.1 - 1.4e-42 145.6 10.2 3.5e-42 144.3 1.0 2.6 3 0 0 3 3 3 2 Phostensin PP1-binding and SH3-binding region DUF4347 PF14252.6 KFP05085.1 - 0.00028 20.8 0.0 0.00049 20.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4347) IQ PF00612.27 KFP05085.1 - 0.05 13.4 12.3 0.15 11.9 0.1 4.0 4 0 0 4 4 4 0 IQ calmodulin-binding motif MCM3AP_GANP PF16769.5 KFP05085.1 - 0.13 10.5 0.3 0.19 10.0 0.3 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP MRP-L27 PF09809.9 KFP05086.1 - 7.3e-44 148.2 0.0 8.3e-44 148.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 WD40 PF00400.32 KFP05087.1 - 2.4e-07 31.3 4.8 0.11 13.4 0.0 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat zf-MYND PF01753.18 KFP05088.1 - 2.8e-07 30.5 15.2 4.4e-07 29.9 15.2 1.4 1 0 0 1 1 1 1 MYND finger HNH_3 PF13392.6 KFP05088.1 - 2.7e-05 23.9 0.2 5.9e-05 22.7 0.2 1.6 1 0 0 1 1 1 1 HNH endonuclease SHIPPO-rpt PF07004.12 KFP05090.1 - 0.036 15.0 0.2 0.078 13.9 0.2 1.7 1 1 0 1 1 1 0 Sperm-tail PG-rich repeat Ribosomal_L11 PF00298.19 KFP05091.1 - 5.8e-18 65.2 0.2 8e-18 64.7 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KFP05091.1 - 1e-10 41.3 0.0 1.7e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain LRR_8 PF13855.6 KFP05092.1 - 6.3e-21 73.9 13.2 2.3e-12 46.5 4.5 3.8 3 1 1 4 4 4 3 Leucine rich repeat zf-C3HC4_3 PF13920.6 KFP05092.1 - 2.4e-11 43.3 20.3 2.4e-11 43.3 20.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) LRR_4 PF12799.7 KFP05092.1 - 4e-09 36.6 16.5 2.7e-06 27.6 3.5 4.2 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) SAM_1 PF00536.30 KFP05092.1 - 7.4e-06 26.3 0.6 0.00013 22.4 0.0 2.9 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) Prok-RING_4 PF14447.6 KFP05092.1 - 1e-05 25.3 18.7 2.5e-05 24.0 18.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 SAM_2 PF07647.17 KFP05092.1 - 0.0017 18.4 0.2 0.013 15.6 0.0 2.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) LRR_1 PF00560.33 KFP05092.1 - 0.0066 16.8 9.2 20 6.2 0.1 5.9 6 0 0 6 6 6 2 Leucine Rich Repeat Ctr PF04145.15 KFP05093.1 - 5.9e-33 114.6 7.1 1.5e-32 113.3 7.1 1.6 1 1 0 1 1 1 1 Ctr copper transporter family HAD_2 PF13419.6 KFP05094.1 - 1.6e-16 60.9 0.0 1.8e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFP05094.1 - 1.8e-12 48.0 0.0 2e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFP05094.1 - 8.2e-09 35.4 0.0 1.5e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like ALAD PF00490.21 KFP05095.1 - 4.7e-115 384.1 0.0 5.8e-115 383.8 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase CBFD_NFYB_HMF PF00808.23 KFP05096.1 - 2.8e-07 30.7 0.0 5.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SpoU_methylase PF00588.19 KFP05096.1 - 0.0042 17.2 0.0 0.0053 16.9 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family DUF4746 PF15928.5 KFP05096.1 - 0.029 13.8 8.0 0.029 13.8 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Histone PF00125.24 KFP05096.1 - 0.034 14.5 7.3 0.069 13.5 0.0 2.1 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Myc_N PF01056.18 KFP05096.1 - 0.065 13.1 6.5 0.061 13.2 6.5 1.1 1 0 0 1 1 1 0 Myc amino-terminal region BUD22 PF09073.10 KFP05096.1 - 0.096 12.0 14.9 0.1 11.9 14.9 1.1 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.14 KFP05096.1 - 0.1 12.4 10.8 0.11 12.3 10.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOA36 PF06524.12 KFP05096.1 - 0.15 11.4 10.8 0.15 11.4 10.8 1.1 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.12 KFP05096.1 - 0.18 11.2 16.2 0.21 10.9 16.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Afi1 PF07792.12 KFP05096.1 - 0.21 12.1 11.7 0.29 11.6 11.7 1.3 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CDC45 PF02724.14 KFP05096.1 - 0.56 8.4 9.8 0.52 8.5 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2956 PF11169.8 KFP05096.1 - 0.67 10.2 8.1 1 9.6 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Vfa1 PF08432.10 KFP05096.1 - 0.83 10.0 14.6 0.98 9.7 14.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF913 PF06025.12 KFP05096.1 - 0.87 8.5 4.1 0.79 8.6 4.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RPN2_C PF18004.1 KFP05096.1 - 0.92 9.4 12.0 0.97 9.3 12.0 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain V_ATPase_I PF01496.19 KFP05096.1 - 1.1 7.0 4.4 1 7.2 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 KFP05096.1 - 1.4 8.6 3.9 1.4 8.6 3.9 1.2 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 KFP05096.1 - 1.5 7.5 6.1 1.4 7.6 6.1 1.1 1 0 0 1 1 1 0 Presenilin DNA_pol_phi PF04931.13 KFP05096.1 - 1.5 6.8 21.5 1.7 6.6 21.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi Serinc PF03348.15 KFP05096.1 - 1.6 7.6 2.9 1.7 7.5 2.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) NPR3 PF03666.13 KFP05096.1 - 4.1 6.1 8.6 4.5 5.9 8.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 C2 PF00168.30 KFP05097.1 - 4.5e-18 65.4 0.1 5.9e-18 65.1 0.1 1.2 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.6 KFP05097.1 - 0.0027 17.3 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 CEP76 C2 domain RGS PF00615.19 KFP05098.1 - 5.8e-39 133.0 4.1 6.5e-39 132.9 4.1 1.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain Rod_C PF10493.9 KFP05098.1 - 0.036 12.5 1.0 0.04 12.3 1.0 1.0 1 0 0 1 1 1 0 Rough deal protein C-terminal region Inhibitor_I10 PF12559.8 KFP05098.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Serine endopeptidase inhibitors zf-C2H2_4 PF13894.6 KFP05099.1 - 1.5e-09 37.9 23.4 0.029 15.2 2.3 5.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP05099.1 - 1.2e-07 31.8 28.3 0.13 12.8 2.9 5.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type Dimer_Tnp_hAT PF05699.14 KFP05099.1 - 2e-05 24.3 0.2 6.3e-05 22.7 0.2 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DBD_Tnp_Hermes PF10683.9 KFP05099.1 - 0.086 12.5 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain C1_2 PF03107.16 KFP05099.1 - 0.088 13.1 27.4 0.31 11.4 2.4 5.2 5 0 0 5 5 5 0 C1 domain DUF4413 PF14372.6 KFP05099.1 - 0.096 13.1 0.0 0.26 11.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) zf_UBZ PF18439.1 KFP05099.1 - 0.15 11.7 14.1 0.53 9.9 1.3 4.5 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger RNA_pol_Rpb1_1 PF04997.12 KFP05099.1 - 0.19 11.1 5.4 3.4 6.9 0.1 3.5 3 0 0 3 3 3 0 RNA polymerase Rpb1, domain 1 zf-C2H2_3rep PF18868.1 KFP05099.1 - 0.27 11.9 5.8 1.1 10.0 0.0 3.9 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-BED PF02892.15 KFP05099.1 - 1.4 9.0 24.6 1.9 8.6 2.9 4.9 5 0 0 5 5 5 0 BED zinc finger ANF_receptor PF01094.28 KFP05100.1 - 1.5e-33 116.4 0.0 1.5e-31 109.8 0.0 2.3 1 1 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 KFP05100.1 - 1.5e-32 112.5 0.1 2.6e-32 111.7 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFP05100.1 - 6.9e-32 110.0 0.1 3.8e-30 104.4 0.0 2.5 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFP05100.1 - 2e-19 69.9 0.0 4.5e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 CaM_bdg_C0 PF10562.9 KFP05100.1 - 9.6e-14 51.1 3.9 2.2e-13 50.0 3.9 1.7 1 0 0 1 1 1 1 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit Peripla_BP_6 PF13458.6 KFP05100.1 - 0.0063 16.2 0.0 0.17 11.5 0.0 2.2 2 0 0 2 2 2 1 Periplasmic binding protein zf-RING_2 PF13639.6 KFP05101.1 - 1.1e-07 32.0 6.1 1.1e-07 32.0 6.1 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KFP05101.1 - 1.9e-07 31.0 1.0 1.9e-07 31.0 1.0 2.4 2 2 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP05102.1 - 0.0018 18.2 13.8 0.0018 18.2 13.8 2.9 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFP05102.1 - 0.0028 17.9 11.8 0.0028 17.9 11.8 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KFP05102.1 - 0.003 17.6 11.2 0.003 17.6 11.2 2.8 2 1 1 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFP05102.1 - 0.01 15.7 14.1 0.01 15.7 14.1 3.0 2 2 1 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFP05102.1 - 0.018 14.9 14.1 0.018 14.9 14.1 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GcpE PF04551.14 KFP05102.1 - 0.24 10.4 5.4 0.044 12.9 1.0 1.8 1 1 1 2 2 2 0 GcpE protein ADK_lid PF05191.14 KFP05102.1 - 4 7.5 9.0 0.95 9.5 3.2 2.5 2 1 0 2 2 2 0 Adenylate kinase, active site lid Zn_Tnp_IS1595 PF12760.7 KFP05102.1 - 5.2 7.1 15.5 1.8 8.6 2.1 3.0 2 2 1 3 3 3 0 Transposase zinc-ribbon domain zf-RING_5 PF14634.6 KFP05103.1 - 5.6e-09 35.8 5.2 8.5e-09 35.2 5.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFP05103.1 - 6.3e-09 35.7 2.5 6.3e-09 35.7 2.5 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFP05103.1 - 1.5e-08 34.9 6.5 2.5e-08 34.1 6.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFP05103.1 - 1.8e-08 34.1 5.3 3.2e-08 33.3 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP05103.1 - 1.9e-07 30.8 7.5 8.5e-07 28.7 7.5 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFP05103.1 - 9.5e-07 28.9 3.2 2.3e-06 27.7 3.2 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KFP05103.1 - 1.1e-05 25.1 5.3 2.8e-05 23.8 5.4 1.6 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KFP05103.1 - 1.6e-05 24.7 8.2 0.00064 19.5 8.7 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFP05103.1 - 0.0051 16.8 3.0 0.0079 16.2 3.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KFP05103.1 - 0.0054 17.0 4.9 0.006 16.9 4.1 1.5 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KFP05103.1 - 0.018 14.9 11.4 0.28 11.0 11.6 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) NMD3 PF04981.13 KFP05103.1 - 0.018 14.5 3.3 0.022 14.2 3.3 1.1 1 0 0 1 1 1 0 NMD3 family DUF4428 PF14471.6 KFP05103.1 - 0.027 14.4 3.4 0.45 10.5 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) zf-P11 PF03854.14 KFP05103.1 - 0.046 13.4 10.0 0.13 11.9 3.5 2.7 1 1 1 2 2 2 0 P-11 zinc finger zf-RING_11 PF17123.5 KFP05103.1 - 0.086 12.6 0.3 0.086 12.6 0.3 2.4 3 0 0 3 3 3 0 RING-like zinc finger Gin PF10764.9 KFP05103.1 - 0.14 12.2 3.4 0.17 11.9 0.1 2.3 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin DZR PF12773.7 KFP05103.1 - 0.15 12.1 5.8 2 8.5 5.9 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_10 PF16685.5 KFP05103.1 - 0.22 11.7 5.9 0.56 10.4 6.0 1.8 1 1 0 1 1 1 0 zinc RING finger of MSL2 Zn-C2H2_12 PF18112.1 KFP05103.1 - 0.31 11.5 4.1 3 8.4 0.3 2.4 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-Sec23_Sec24 PF04810.15 KFP05103.1 - 0.44 10.7 5.6 0.31 11.1 1.6 2.3 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger zf-WRNIP1_ubi PF18279.1 KFP05103.1 - 0.78 10.5 0.3 0.78 10.5 0.3 2.7 2 1 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain YacG PF03884.14 KFP05103.1 - 6.2 6.6 10.7 2.8 7.7 1.0 2.3 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG zf-Di19 PF05605.12 KFP05103.1 - 6.7 7.1 7.9 13 6.2 2.0 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FAD_binding_1 PF00667.20 KFP05104.1 - 2.5e-47 161.3 0.0 3.7e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFP05104.1 - 1e-33 116.6 0.0 1.6e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KFP05104.1 - 3.5e-16 59.8 0.0 7e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Tmemb_185A PF10269.9 KFP05105.1 - 1e-05 25.3 6.7 1e-05 25.3 6.7 1.8 1 1 0 1 1 1 1 Transmembrane Fragile-X-F protein GDA1_CD39 PF01150.17 KFP05106.1 - 9.8e-102 340.8 0.0 1.2e-101 340.4 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family SH3_1 PF00018.28 KFP05107.1 - 2.1e-16 59.2 0.0 8.2e-13 47.7 0.0 2.3 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KFP05107.1 - 3e-10 39.8 0.0 5.9e-08 32.5 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KFP05107.1 - 2.8e-07 30.1 0.0 0.00028 20.5 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.24 KFP05107.1 - 0.0001 22.2 0.0 0.00018 21.4 0.0 1.4 1 0 0 1 1 1 1 PB1 domain TPR_2 PF07719.17 KFP05108.1 - 1.6e-08 34.0 1.7 0.0054 16.8 0.0 3.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFP05108.1 - 4.1e-07 29.5 0.0 0.0017 18.1 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFP05108.1 - 8e-06 26.1 1.8 0.036 14.4 1.9 2.3 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFP05108.1 - 0.00018 21.6 0.2 0.23 11.7 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFP05108.1 - 0.0005 19.9 0.3 0.035 14.1 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFP05108.1 - 0.014 15.3 0.2 4.8 7.2 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFP05108.1 - 0.018 15.6 0.3 0.31 11.8 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP05108.1 - 0.029 14.6 1.2 0.16 12.2 0.4 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KFP05108.1 - 0.059 13.9 0.8 0.2 12.2 0.8 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFP05108.1 - 0.076 13.9 0.8 1.8 9.6 0.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DNA_pol_A_exo1 PF01612.20 KFP05109.1 - 2.3e-20 73.1 0.1 5.5e-20 71.8 0.1 1.7 1 0 0 1 1 1 1 3'-5' exonuclease Mut7-C PF01927.16 KFP05109.1 - 1.6e-13 51.0 1.5 1.9e-13 50.8 0.2 1.9 2 0 0 2 2 2 1 Mut7-C RNAse domain Fels1 PF05666.11 KFP05109.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Fels-1 Prophage Protein-like Kunitz_BPTI PF00014.23 KFP05110.1 - 7.7e-35 118.9 21.7 2.5e-17 62.8 7.2 2.6 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Lipocalin PF00061.23 KFP05110.1 - 2.1e-27 96.1 0.0 2.9e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Megourin PF17560.2 KFP05110.1 - 1.3 9.3 10.3 1.2 9.4 3.3 2.4 2 0 0 2 2 2 0 Aphid Megourins Ras PF00071.22 KFP05111.1 - 8.3e-12 45.0 0.1 1.1e-05 25.1 0.3 2.3 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KFP05111.1 - 4.1e-07 30.2 1.0 4.1e-07 30.2 1.0 2.7 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP05111.1 - 6.6e-06 25.7 0.1 2.2e-05 24.0 0.1 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP05111.1 - 0.00012 22.1 0.0 0.00045 20.3 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KFP05111.1 - 0.065 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation zf-MYND PF01753.18 KFP05112.1 - 0.00045 20.2 15.9 0.00089 19.3 15.9 1.5 1 0 0 1 1 1 1 MYND finger Ocnus PF05005.15 KFP05113.1 - 1.2e-23 83.3 0.0 1.3e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) MBF1 PF08523.10 KFP05114.1 - 1.6e-25 89.4 5.1 3.7e-25 88.2 5.1 1.6 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KFP05114.1 - 1.7e-12 47.2 0.2 2.6e-12 46.6 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KFP05114.1 - 0.00027 21.2 0.0 0.00045 20.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KFP05114.1 - 0.041 13.9 0.2 0.063 13.3 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 KFP05114.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain BTB PF00651.31 KFP05115.1 - 9e-27 93.5 0.0 1.6e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFP05115.1 - 4.2e-09 36.4 16.2 2.1e-06 27.9 0.6 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFP05115.1 - 0.00035 20.9 27.8 0.0015 18.8 2.5 4.4 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP05115.1 - 0.0011 19.6 21.4 0.031 15.1 1.8 4.3 3 0 0 3 3 3 2 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 KFP05115.1 - 0.0032 17.4 2.9 0.0032 17.4 2.9 1.9 2 0 0 2 2 2 1 SprT-like zinc ribbon domain zf-C2H2_8 PF15909.5 KFP05115.1 - 0.13 12.6 7.8 0.51 10.7 5.2 2.8 3 0 0 3 3 3 0 C2H2-type zinc ribbon zf-met PF12874.7 KFP05115.1 - 0.72 10.3 11.1 11 6.5 0.7 3.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type BTB PF00651.31 KFP05116.1 - 6e-26 90.8 0.2 9.7e-26 90.2 0.2 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 KFP05116.1 - 6.9e-17 60.9 16.9 3.7e-05 24.0 2.1 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP05116.1 - 2.1e-14 53.2 16.9 2e-07 31.1 0.6 4.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP05116.1 - 7.2e-13 48.2 14.8 0.00036 21.1 0.3 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFP05116.1 - 1.2e-08 35.0 7.2 0.0042 17.4 0.2 3.9 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP05116.1 - 6.8e-06 26.2 6.3 0.26 11.6 0.0 3.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding DUF3342 PF11822.8 KFP05116.1 - 1.2e-05 25.4 0.1 2.6e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) zf-C2H2_11 PF16622.5 KFP05116.1 - 1.7e-05 24.4 14.2 0.0052 16.5 0.2 4.1 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-BED PF02892.15 KFP05116.1 - 0.00048 20.1 15.4 0.31 11.1 0.7 3.7 1 1 2 3 3 3 2 BED zinc finger DUF4187 PF13821.6 KFP05116.1 - 0.0054 16.5 0.5 1.6 8.6 0.1 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) zf-C2H2_6 PF13912.6 KFP05116.1 - 0.021 14.8 11.4 0.71 9.9 0.8 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFP05116.1 - 0.024 15.0 10.8 0.14 12.5 0.1 3.9 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 KFP05116.1 - 0.034 13.9 5.6 1.2 9.0 0.1 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Chordopox_A33R PF05966.12 KFP05116.1 - 0.046 13.0 0.1 0.086 12.1 0.1 1.4 1 0 0 1 1 1 0 Chordopoxvirus A33R protein PyrI_C PF02748.15 KFP05116.1 - 0.46 10.4 7.3 7.4 6.6 0.1 3.4 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-Di19 PF05605.12 KFP05116.1 - 0.7 10.2 9.0 0.4 11.0 2.8 2.9 2 1 1 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding HNH_5 PF14279.6 KFP05116.1 - 2.2 8.2 7.3 5.5 6.9 0.1 3.3 3 0 0 3 3 3 0 HNH endonuclease zf_UBZ PF18439.1 KFP05116.1 - 3.2 7.4 5.6 4 7.1 0.3 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 KFP05116.1 - 3.3 7.7 12.0 3.3 7.7 0.1 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_3rep PF18868.1 KFP05116.1 - 3.7 8.2 8.8 19 6.0 0.6 3.4 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2HE PF16278.5 KFP05116.1 - 5.6 7.5 9.5 7 7.2 0.1 3.4 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-AN1 PF01428.16 KFP05116.1 - 9.1 6.5 10.4 5.1 7.3 0.2 3.7 3 0 0 3 3 3 0 AN1-like Zinc finger RasGEF PF00617.19 KFP05117.1 - 3e-51 174.1 2.5 1.3e-50 172.0 1.4 2.0 1 1 1 2 2 2 1 RasGEF domain PH PF00169.29 KFP05117.1 - 8.7e-11 42.3 0.0 2e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 PH domain Fibrinogen_C PF00147.18 KFP05118.1 - 6.9e-75 251.6 12.3 9.6e-75 251.2 12.3 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fer4_NifH PF00142.18 KFP05118.1 - 0.017 14.6 1.5 0.05 13.0 1.8 1.6 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF16 PF01519.16 KFP05118.1 - 3 8.4 12.9 2.1 8.9 5.0 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 LMBR1 PF04791.16 KFP05118.1 - 9.8 5.0 6.3 13 4.5 6.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein WD40 PF00400.32 KFP05119.1 - 8.5e-16 58.1 11.0 1.4e-05 25.7 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat F-box-like PF12937.7 KFP05119.1 - 4.5e-08 32.9 4.7 1.7e-07 31.0 3.2 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFP05119.1 - 2.1e-05 24.3 1.5 8.1e-05 22.4 0.7 2.3 1 1 1 2 2 2 1 F-box domain Rap_GAP PF02145.15 KFP05120.1 - 8.3e-68 227.6 0.1 1.6e-67 226.7 0.1 1.5 1 0 0 1 1 1 1 Rap/ran-GAP CNH PF00780.22 KFP05120.1 - 6.5e-66 222.8 0.2 1.4e-65 221.7 0.2 1.6 1 0 0 1 1 1 1 CNH domain HEPN_STY4199 PF18729.1 KFP05120.1 - 0.082 12.1 0.4 2.4 7.3 0.1 2.2 2 0 0 2 2 2 0 STY4199-like HEPN Laminin_G_3 PF13385.6 KFP05121.1 - 2.7e-21 76.3 0.0 5.2e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Sushi PF00084.20 KFP05121.1 - 1.2e-20 73.9 48.0 1.6e-07 31.8 3.7 8.9 7 2 1 8 8 8 4 Sushi repeat (SCR repeat) Peptidase_M43 PF05572.13 KFP05121.1 - 6.4e-08 32.6 0.8 2.2e-07 30.9 0.1 2.4 1 1 1 2 2 2 1 Pregnancy-associated plasma protein-A DUF4215 PF13948.6 KFP05121.1 - 0.00023 21.5 5.9 0.00023 21.5 5.9 8.3 9 1 0 9 9 9 1 Domain of unknown function (DUF4215) Notch PF00066.17 KFP05121.1 - 0.0004 20.8 5.0 0.0004 20.8 5.0 6.9 7 0 0 7 7 7 3 LNR domain Reprolysin_3 PF13582.6 KFP05121.1 - 0.0051 17.3 0.2 0.013 16.0 0.2 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP05121.1 - 0.076 12.7 0.1 0.23 11.1 0.1 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFP05121.1 - 0.67 9.8 1.9 1.7 8.5 1.9 1.6 1 0 0 1 1 1 0 Matrixin Annexin_like PF18411.1 KFP05122.1 - 8.7e-55 183.0 0.1 2.4e-54 181.6 0.1 1.8 1 0 0 1 1 1 1 Annexin-like domain ASTN_2_hairpin PF18577.1 KFP05122.1 - 2.3e-27 94.8 0.6 5.3e-27 93.7 0.6 1.7 1 0 0 1 1 1 1 Astrotactin-2 C-terminal beta-hairpin domain FXa_inhibition PF14670.6 KFP05122.1 - 3.1e-11 43.4 43.5 1.1e-10 41.6 4.0 4.1 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site MACPF PF01823.19 KFP05122.1 - 3.1e-07 30.7 0.6 1.7e-06 28.3 0.2 2.1 2 0 0 2 2 2 1 MAC/Perforin domain cEGF PF12662.7 KFP05122.1 - 0.003 17.4 5.1 0.14 12.1 0.4 3.2 2 0 0 2 2 2 2 Complement Clr-like EGF-like Herpes_gE PF02480.16 KFP05122.1 - 0.022 13.5 0.0 0.051 12.3 0.0 1.6 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E fn3 PF00041.21 KFP05122.1 - 0.028 14.8 0.0 0.11 12.9 0.0 1.9 1 1 0 1 1 1 0 Fibronectin type III domain MAP17 PF15807.5 KFP05122.1 - 0.19 11.9 0.0 0.5 10.6 0.0 1.7 1 1 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Frag1 PF10277.9 KFP05122.1 - 0.23 11.0 0.5 7.8 6.0 0.1 2.3 2 0 0 2 2 2 0 Frag1/DRAM/Sfk1 family NHL PF01436.21 KFP05123.1 - 1.2e-31 107.1 2.7 4.9e-06 26.3 0.1 5.9 5 0 0 5 5 5 5 NHL repeat zf-RING_UBOX PF13445.6 KFP05123.1 - 3.4e-10 39.8 7.4 3.4e-10 39.8 7.4 2.7 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFP05123.1 - 5.5e-09 36.2 9.2 5.5e-09 36.2 9.2 3.0 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.6 KFP05123.1 - 4.8e-07 29.6 9.1 4.8e-07 29.6 9.1 3.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFP05123.1 - 2.6e-06 27.2 10.4 2.6e-06 27.2 10.4 3.0 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 KFP05123.1 - 4e-05 23.7 3.5 4e-05 23.7 3.5 3.2 3 1 0 3 3 2 1 B-box zinc finger zf-C3HC4_4 PF15227.6 KFP05123.1 - 0.00012 22.1 8.6 0.00012 22.1 8.6 3.1 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 KFP05123.1 - 0.00012 22.0 0.8 0.00012 22.0 0.8 2.4 3 0 0 3 3 3 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_2 PF13923.6 KFP05123.1 - 0.00014 21.7 9.7 0.00014 21.7 9.7 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KFP05123.1 - 0.00035 20.3 5.8 0.00035 20.3 5.8 2.6 3 0 0 3 3 2 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KFP05123.1 - 0.001 18.9 9.8 0.001 18.9 9.8 3.9 4 1 1 5 5 4 1 Prokaryotic RING finger family 4 SGL PF08450.12 KFP05123.1 - 0.0013 18.4 0.0 22 4.5 0.0 3.9 2 1 2 4 4 4 0 SMP-30/Gluconolactonase/LRE-like region OmpH PF03938.14 KFP05123.1 - 0.023 15.0 4.4 0.038 14.3 4.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Borrelia_lipo_1 PF05714.11 KFP05123.1 - 0.051 13.3 0.5 0.078 12.7 0.5 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein zf-RING_11 PF17123.5 KFP05123.1 - 0.07 12.9 6.7 0.23 11.2 6.7 2.0 1 0 0 1 1 1 0 RING-like zinc finger Zn_Tnp_IS1595 PF12760.7 KFP05123.1 - 0.51 10.4 0.0 0.51 10.4 0.0 3.6 4 0 0 4 4 3 0 Transposase zinc-ribbon domain FYVE PF01363.21 KFP05123.1 - 1.4 9.1 27.0 1.2e+03 -0.3 20.2 3.0 2 1 0 2 2 1 0 FYVE zinc finger CEBP_ZZ PF16366.5 KFP05123.1 - 1.6 9.0 11.9 3 8.2 1.8 3.5 3 0 0 3 3 3 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Rad50_zn_hook PF04423.14 KFP05123.1 - 3.4 7.6 7.1 1.1 9.2 0.3 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif LRR_8 PF13855.6 KFP05124.1 - 1.3e-48 162.5 58.7 2.7e-12 46.3 3.0 9.7 6 4 4 10 10 10 9 Leucine rich repeat TIR PF01582.20 KFP05124.1 - 4e-21 75.6 0.1 7.6e-21 74.7 0.1 1.4 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 KFP05124.1 - 1.2e-19 70.0 60.6 4.3e-05 23.8 3.8 10.7 4 3 6 11 11 11 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP05124.1 - 3.7e-13 49.5 0.1 3.6e-07 30.2 0.1 5.5 2 2 4 6 6 6 4 BspA type Leucine rich repeat region (6 copies) TIR_2 PF13676.6 KFP05124.1 - 4.9e-11 43.3 0.0 1.7e-10 41.5 0.0 1.9 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.33 KFP05124.1 - 1.3e-05 25.0 52.8 3.8 8.4 0.3 14.0 14 1 0 14 14 14 3 Leucine Rich Repeat LRR_9 PF14580.6 KFP05124.1 - 7e-05 22.4 16.2 0.053 13.0 0.4 4.3 2 1 2 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 KFP05124.1 - 0.48 10.6 54.1 0.93 9.7 0.4 12.1 14 0 0 14 14 14 0 Leucine Rich repeat Col_cuticle_N PF01484.17 KFP05124.1 - 0.68 10.0 4.3 2 8.5 4.3 1.8 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Yae1_N PF09811.9 KFP05125.1 - 3.6e-10 39.4 30.4 34 4.2 30.4 3.2 1 1 0 1 1 1 1 Essential protein Yae1, N terminal Biliv-reduc_cat PF09166.10 KFP05127.1 - 9.6e-58 193.4 0.0 1.5e-57 192.8 0.0 1.3 1 0 0 1 1 1 1 Biliverdin reductase, catalytic GFO_IDH_MocA PF01408.22 KFP05127.1 - 9.2e-18 65.2 0.4 2.4e-17 63.9 0.2 1.8 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold HECT PF00632.25 KFP05128.1 - 4.2e-103 345.1 0.0 6e-103 344.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECW_N PF16562.5 KFP05128.1 - 3.6e-59 197.8 0.6 7.9e-59 196.7 0.6 1.6 1 0 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 HECW1_helix PF18436.1 KFP05128.1 - 7.6e-38 128.5 4.4 8.3e-35 118.7 2.7 2.7 2 0 0 2 2 2 2 Helical box domain of E3 ubiquitin-protein ligase HECW1 WW PF00397.26 KFP05128.1 - 2.1e-17 62.9 0.5 8.9e-10 38.5 0.5 2.7 2 0 0 2 2 2 2 WW domain C2 PF00168.30 KFP05128.1 - 5.3e-11 42.7 0.0 2e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 C2 domain Keratin_B2_2 PF13885.6 KFP05128.1 - 1.6 8.7 22.3 5.3 7.1 22.3 1.9 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein RFXA_RFXANK_bdg PF15289.6 KFP05128.1 - 8.9 6.7 8.4 1.4 9.2 0.1 2.9 3 0 0 3 3 3 0 Regulatory factor X-associated C-terminal binding domain Ribosomal_L32p PF01783.23 KFP05129.1 - 2.5e-08 34.1 7.4 3.9e-08 33.4 7.4 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family RecR PF02132.15 KFP05129.1 - 0.00028 20.4 1.0 0.0005 19.6 1.0 1.4 1 0 0 1 1 1 1 RecR protein DZR PF12773.7 KFP05129.1 - 0.065 13.3 1.6 0.17 11.9 1.0 1.8 1 1 1 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KFP05129.1 - 0.094 12.2 2.1 0.2 11.1 2.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Proteasome PF00227.26 KFP05130.1 - 1.9e-60 203.6 0.0 2.5e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFP05130.1 - 1.8e-05 24.3 0.1 3.1e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PBP_dimer PF03717.15 KFP05130.1 - 0.049 14.0 0.0 6.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Penicillin-binding Protein dimerisation domain DUF5614 PF18474.1 KFP05131.1 - 1.1e-125 417.3 0.8 1.7e-125 416.6 0.8 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5614) DUF1308 PF07000.11 KFP05131.1 - 3.3e-71 238.5 0.1 1.3e-70 236.6 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) Yae1_N PF09811.9 KFP05134.1 - 4.9e-11 42.1 68.3 1.8e+04 -38.4 68.3 6.5 1 1 0 1 1 1 0 Essential protein Yae1, N terminal LAMTOR5 PF16672.5 KFP05135.1 - 7.4e-34 115.5 0.7 8.1e-34 115.4 0.7 1.0 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 Robl_LC7 PF03259.17 KFP05135.1 - 0.033 13.9 0.0 0.04 13.7 0.0 1.1 1 0 0 1 1 1 0 Roadblock/LC7 domain MFS_1 PF07690.16 KFP05136.1 - 2.6e-32 112.1 35.6 5.4e-18 65.1 15.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SPOC PF07744.13 KFP05137.1 - 1.6e-38 132.0 0.0 2.5e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 SPOC domain RRM_1 PF00076.22 KFP05137.1 - 8.5e-20 70.4 0.0 1.5e-12 47.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFP05137.1 - 7.5e-07 29.1 0.0 0.00063 19.7 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KFP05137.1 - 0.00052 20.0 0.0 0.0052 16.8 0.0 2.2 1 1 1 2 2 2 1 RNA binding motif RRM_7 PF16367.5 KFP05137.1 - 0.035 14.2 0.0 3.5 7.8 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif Ion_trans PF00520.31 KFP05138.1 - 1.1e-42 146.0 16.9 1.4e-42 145.6 16.9 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFP05138.1 - 1.4e-28 99.1 0.0 3.1e-28 98.0 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFP05138.1 - 1.4e-10 40.9 9.1 2.1e-10 40.4 4.6 2.5 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.5 KFP05138.1 - 0.00089 19.3 0.0 0.0033 17.5 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain PKD_channel PF08016.12 KFP05138.1 - 2.1 6.9 7.5 0.22 10.1 1.5 1.9 1 1 1 2 2 2 0 Polycystin cation channel SNF PF00209.18 KFP05139.1 - 3.2e-222 738.9 34.3 3.9e-222 738.6 34.3 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Tmemb_18A PF09771.9 KFP05139.1 - 0.39 11.1 0.1 0.39 11.1 0.1 3.2 4 0 0 4 4 4 0 Transmembrane protein 188 Homeodomain PF00046.29 KFP05140.1 - 9.3e-25 86.3 7.3 1.1e-24 86.0 7.3 1.1 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP05140.1 - 7.7e-05 22.5 0.2 0.00015 21.6 0.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain DUF3402 PF11882.8 KFP05141.1 - 6e-101 338.8 24.7 2e-65 221.7 5.2 3.6 2 1 2 4 4 4 3 Domain of unknown function (DUF3402) N1221 PF07923.13 KFP05141.1 - 8.2e-36 123.7 0.0 1.6e-35 122.7 0.0 1.5 1 0 0 1 1 1 1 N1221-like protein ELM2 PF01448.24 KFP05141.1 - 0.081 13.7 0.4 0.21 12.3 0.4 1.7 1 0 0 1 1 1 0 ELM2 domain AdoHcyase PF05221.17 KFP05142.1 - 1.2e-29 103.4 0.8 9.9e-27 93.8 0.8 2.1 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase SR-25 PF10500.9 KFP05142.1 - 0.13 11.8 6.4 0.17 11.5 6.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF515 PF04415.12 KFP05142.1 - 0.41 9.0 4.4 0.52 8.6 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) GST_C_3 PF14497.6 KFP05143.1 - 1.6e-16 60.3 0.1 2.2e-16 59.9 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFP05143.1 - 2.4e-16 59.7 0.1 3.5e-16 59.2 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFP05143.1 - 2.3e-06 27.9 0.0 5.3e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KFP05143.1 - 2e-05 24.3 0.5 5.4e-05 22.9 0.5 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFP05143.1 - 0.00021 21.3 0.0 0.00046 20.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFP05143.1 - 0.059 13.8 0.0 0.13 12.7 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain YpzG PF14139.6 KFP05143.1 - 0.15 12.2 0.0 0.4 10.9 0.0 1.7 1 0 0 1 1 1 0 YpzG-like protein A_deaminase PF00962.22 KFP05144.1 - 1.1e-130 435.8 1.4 2.5e-130 434.6 1.4 1.5 1 1 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 KFP05144.1 - 0.072 12.4 0.1 3.4 6.9 0.0 2.2 2 0 0 2 2 2 0 Amidohydrolase family G-alpha PF00503.20 KFP05145.1 - 2.2e-116 388.9 2.5 2.5e-116 388.7 2.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFP05145.1 - 3.4e-14 52.7 0.4 6.4e-13 48.5 0.1 2.7 2 1 1 3 3 3 1 ADP-ribosylation factor family Proteasome PF00227.26 KFP05146.1 - 4.8e-56 189.3 0.0 5.7e-56 189.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFP05146.1 - 1.4e-11 43.8 0.0 2.3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature tRNA-synt_2b PF00587.25 KFP05147.1 - 1.3e-14 54.6 0.0 1.6e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Cytochrom_C552 PF02335.15 KFP05147.1 - 0.02 13.9 0.2 0.023 13.6 0.2 1.1 1 0 0 1 1 1 0 Cytochrome c552 Shisa PF13908.6 KFP05148.1 - 1.8e-11 44.6 11.6 1.9e-11 44.5 11.6 1.0 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Tropomodulin PF03250.14 KFP05149.1 - 2.2e-08 34.2 5.8 2.2e-08 34.2 5.8 4.0 2 1 1 4 4 4 1 Tropomodulin WH2 PF02205.20 KFP05149.1 - 7.6e-05 22.4 0.4 7.6e-05 22.4 0.4 2.0 2 0 0 2 2 2 1 WH2 motif LRR_6 PF13516.6 KFP05149.1 - 0.0096 15.9 0.8 0.069 13.2 0.1 2.5 2 0 0 2 2 2 1 Leucine Rich repeat Tim17 PF02466.19 KFP05150.1 - 2.5e-31 108.3 5.1 3.2e-31 108.0 5.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HlyIII PF03006.20 KFP05151.1 - 3.9e-73 245.9 19.5 4.7e-73 245.6 19.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4405 PF14358.6 KFP05151.1 - 0.012 16.1 3.4 0.012 16.1 3.4 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4405) DUF962 PF06127.11 KFP05151.1 - 1.6 8.8 9.2 0.058 13.5 1.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF962) UQ_con PF00179.26 KFP05152.1 - 6.7e-37 126.3 0.0 7.4e-37 126.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KFP05152.1 - 0.0048 16.8 0.1 0.0093 15.8 0.1 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 KFP05152.1 - 0.013 15.8 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 KFP05152.1 - 0.017 14.8 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Frag1 PF10277.9 KFP05153.1 - 1.7e-46 158.5 18.5 1.9e-46 158.3 18.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family TMEM70 PF06979.12 KFP05153.1 - 0.067 13.6 4.5 0.24 11.8 0.9 2.3 2 0 0 2 2 2 0 Assembly, mitochondrial proton-transport ATP synth complex TssN PF17555.2 KFP05153.1 - 0.15 11.4 11.8 0.26 10.6 11.8 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssN TMEMspv1-c74-12 PF11044.8 KFP05153.1 - 1.7 8.7 4.5 6.8 6.8 0.0 3.1 3 0 0 3 3 3 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Bac_export_2 PF01312.19 KFP05153.1 - 1.8 7.7 5.8 2.6 7.1 5.8 1.3 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family CDP-OH_P_transf PF01066.21 KFP05154.1 - 1.2e-18 67.6 0.1 1.2e-18 67.6 0.1 3.1 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase DENN PF02141.21 KFP05155.1 - 3.5e-57 193.4 2.1 6.7e-57 192.5 2.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KFP05155.1 - 9.3e-16 58.3 0.0 2.2e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KFP05155.1 - 9e-10 38.4 2.2 1.8e-09 37.4 2.2 1.5 1 0 0 1 1 1 1 dDENN domain HPD PF05044.12 KFP05155.1 - 0.034 14.0 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 Homeo-prospero domain 7tm_6 PF02949.20 KFP05155.1 - 0.064 12.3 0.1 0.1 11.7 0.1 1.4 1 0 0 1 1 1 0 7tm Odorant receptor SPA PF08616.10 KFP05155.1 - 0.093 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis I-set PF07679.16 KFP05156.1 - 2.2e-33 114.2 0.0 1.4e-16 60.3 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin I-set domain fn3 PF00041.21 KFP05156.1 - 2.9e-20 72.4 0.0 2.4e-14 53.4 0.0 2.6 2 0 0 2 2 2 2 Fibronectin type III domain Ig_3 PF13927.6 KFP05156.1 - 3.8e-20 72.3 0.0 1.7e-10 41.4 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP05156.1 - 1.8e-12 47.4 0.0 4.3e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP05156.1 - 1.4e-07 31.6 0.0 0.0024 18.0 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFP05156.1 - 6.3e-06 26.2 0.1 0.021 14.9 0.0 2.4 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFP05156.1 - 8.5e-05 22.7 0.0 0.25 11.5 0.0 3.1 2 1 1 3 3 3 2 Immunoglobulin V-set domain C1-set PF07654.15 KFP05156.1 - 0.0014 19.0 0.0 1 9.8 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin C1-set domain fn3_2 PF16893.5 KFP05156.1 - 0.012 15.8 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 Fibronectin type III domain DUF2369 PF10179.9 KFP05156.1 - 0.1 13.0 0.0 0.9 10.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) FAP PF07174.11 KFP05156.1 - 3.5 7.0 31.1 5.4 6.4 31.1 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) 7tm_1 PF00001.21 KFP05157.1 - 6e-45 153.6 13.0 6.8e-45 153.4 13.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP05157.1 - 1.5e-10 40.9 10.8 9.2e-10 38.3 10.8 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP05157.1 - 4e-10 39.9 5.9 5.1e-10 39.5 5.9 1.2 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP05157.1 - 5.6e-08 32.7 12.2 5.6e-08 32.7 12.2 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx CcmH PF03918.14 KFP05157.1 - 0.16 11.3 0.3 0.65 9.3 0.0 2.1 3 0 0 3 3 3 0 Cytochrome C biogenesis protein UPF0182 PF03699.13 KFP05157.1 - 0.23 9.5 7.3 0.25 9.4 7.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Renin_r PF07850.14 KFP05157.1 - 0.27 11.8 0.1 0.27 11.8 0.1 1.9 2 0 0 2 2 2 0 Renin receptor-like protein Basic PF01586.16 KFP05158.1 - 8.2e-31 107.0 0.2 1.7e-30 106.0 0.1 1.6 2 0 0 2 2 2 1 Myogenic Basic domain HLH PF00010.26 KFP05158.1 - 8.4e-13 48.1 5.9 1.4e-12 47.4 5.9 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3080 PF11279.8 KFP05158.1 - 0.0013 18.0 0.1 0.0017 17.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3080) SAM_1 PF00536.30 KFP05159.1 - 7e-27 93.7 1.4 3.9e-13 49.6 0.2 4.0 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP05159.1 - 2.4e-25 88.4 1.1 6.8e-11 42.1 0.1 3.9 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) CREPT PF16566.5 KFP05159.1 - 0.0014 18.8 8.3 0.0014 18.8 8.3 5.6 4 2 1 5 5 5 2 Cell-cycle alteration and expression-elevated protein in tumour HWE_HK PF07536.14 KFP05159.1 - 0.029 15.0 1.0 0.029 15.0 1.0 5.4 4 1 0 5 5 5 0 HWE histidine kinase DUF2576 PF10845.8 KFP05159.1 - 0.098 12.3 0.2 0.38 10.4 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) DUF2087 PF09860.9 KFP05159.1 - 5.5 7.2 8.4 0.84 9.8 0.3 3.7 4 1 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2087) F-box-like PF12937.7 KFP05160.1 - 0.036 13.9 2.6 0.08 12.9 2.6 1.6 1 0 0 1 1 1 0 F-box-like Tmemb_9 PF05434.11 KFP05161.1 - 1.1e-48 164.9 0.2 1.6e-48 164.3 0.2 1.3 1 0 0 1 1 1 1 TMEM9 fn3 PF00041.21 KFP05162.1 - 3.2e-58 194.0 12.1 8.2e-16 58.1 0.3 5.1 5 0 0 5 5 5 4 Fibronectin type III domain I-set PF07679.16 KFP05162.1 - 2.2e-54 181.5 0.6 8.7e-17 61.0 0.0 7.2 8 1 1 9 9 9 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP05162.1 - 1.5e-33 115.2 3.8 2.4e-13 50.4 0.1 7.3 8 1 0 8 8 8 4 Immunoglobulin domain Ig_2 PF13895.6 KFP05162.1 - 4.9e-16 58.8 0.0 2.9e-07 30.7 0.0 4.4 4 0 0 4 4 4 2 Immunoglobulin domain Tissue_fac PF01108.17 KFP05162.1 - 2.1e-12 46.8 0.1 0.018 14.9 0.0 4.4 4 0 0 4 4 4 4 Tissue factor ig PF00047.25 KFP05162.1 - 1.1e-11 44.8 2.6 0.012 15.8 0.0 5.8 6 1 0 6 6 6 3 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFP05162.1 - 3.8e-10 40.2 10.8 0.15 12.7 0.1 6.3 5 3 0 5 5 5 4 Purple acid Phosphatase, N-terminal domain Receptor_2B4 PF11465.8 KFP05162.1 - 4.4e-09 36.5 0.0 0.011 15.9 0.0 3.9 3 0 0 3 3 3 2 Natural killer cell receptor 2B4 DUF2369 PF10179.9 KFP05162.1 - 1.2e-06 28.8 0.0 1.2 9.6 0.0 5.6 6 0 0 6 6 6 1 Uncharacterised conserved protein (DUF2369) V-set PF07686.17 KFP05162.1 - 9.6e-05 22.5 0.7 0.71 10.1 0.0 5.6 5 2 0 5 5 4 1 Immunoglobulin V-set domain SusE PF14292.6 KFP05162.1 - 0.0001 22.5 3.3 1.4 9.1 0.0 4.7 4 2 1 5 5 4 2 SusE outer membrane protein C2-set_2 PF08205.12 KFP05162.1 - 0.00015 21.8 0.2 0.35 11.0 0.0 3.1 3 0 0 3 3 2 2 CD80-like C2-set immunoglobulin domain NAR2 PF16974.5 KFP05162.1 - 0.0051 16.2 1.5 17 4.8 0.0 4.4 3 1 1 4 4 4 0 High-affinity nitrate transporter accessory ChitinaseA_N PF08329.10 KFP05162.1 - 0.04 13.6 0.1 8 6.1 0.0 2.9 2 0 0 2 2 2 0 Chitinase A, N-terminal domain Herpes_gE PF02480.16 KFP05162.1 - 0.11 11.3 0.0 1 8.0 0.0 2.4 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein E Arm PF00514.23 KFP05163.1 - 2.9e-29 100.1 5.6 2.8e-09 36.7 0.0 7.6 9 0 0 9 9 9 5 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KFP05163.1 - 4.1e-07 30.4 2.4 0.037 14.5 0.1 5.2 4 1 1 5 5 5 2 HEAT-like repeat HEAT PF02985.22 KFP05163.1 - 0.0021 18.2 1.4 1.2 9.6 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat V-ATPase_H_C PF11698.8 KFP05163.1 - 0.0034 17.5 0.1 0.017 15.3 0.1 2.2 2 0 0 2 2 2 1 V-ATPase subunit H HEAT_2 PF13646.6 KFP05163.1 - 0.0062 16.9 0.4 0.51 10.8 0.0 3.0 2 1 1 3 3 3 1 HEAT repeats Mo25 PF08569.11 KFP05163.1 - 0.011 15.1 0.0 0.026 13.9 0.0 1.8 1 1 0 1 1 1 0 Mo25-like Adaptin_N PF01602.20 KFP05163.1 - 0.039 12.5 0.6 4.1 5.9 0.0 2.6 1 1 0 2 2 2 0 Adaptin N terminal region Arm_2 PF04826.13 KFP05163.1 - 0.42 10.0 1.8 0.75 9.2 0.1 2.2 2 2 0 2 2 2 0 Armadillo-like Troponin PF00992.20 KFP05164.1 - 1.6e-36 125.6 47.6 1.8e-32 112.4 39.3 2.0 1 1 1 2 2 2 2 Troponin UCR_TM PF02921.14 KFP05164.1 - 0.93 10.0 0.1 0.93 10.0 0.1 2.6 3 1 0 3 3 3 0 Ubiquinol cytochrome reductase transmembrane region Troponin PF00992.20 KFP05165.1 - 9.6e-48 161.9 6.3 1.3e-47 161.5 6.3 1.2 1 0 0 1 1 1 1 Troponin Tup_N PF08581.10 KFP05165.1 - 0.022 15.1 0.2 0.022 15.1 0.2 2.1 3 0 0 3 3 3 0 Tup N-terminal XkdW PF09636.10 KFP05165.1 - 0.059 13.5 1.5 0.26 11.4 1.5 2.1 1 1 0 1 1 1 0 XkdW protein ADIP PF11559.8 KFP05165.1 - 0.073 13.2 2.3 0.25 11.4 1.9 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2951 PF11166.8 KFP05165.1 - 0.2 11.9 5.1 0.67 10.2 2.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2951) PH_15 PF17339.2 KFP05166.1 - 4.9e-06 26.4 0.1 1e-05 25.4 0.1 1.5 1 1 0 1 1 1 1 PH domain PH PF00169.29 KFP05166.1 - 3e-05 24.5 0.1 3.7e-05 24.2 0.1 1.1 1 0 0 1 1 1 1 PH domain LIM PF00412.22 KFP05167.1 - 4.6e-30 103.6 25.1 5.1e-17 61.8 5.1 2.1 2 0 0 2 2 2 2 LIM domain zf_UBZ PF18439.1 KFP05167.1 - 0.033 13.8 9.8 1.1 8.9 0.3 4.0 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-ACC PF17848.1 KFP05167.1 - 0.41 10.8 0.2 0.41 10.8 0.2 4.9 6 0 0 6 6 6 0 Acetyl-coA carboxylase zinc finger domain Dynactin_p62 PF05502.13 KFP05167.1 - 1.1 7.9 10.7 1.4 7.6 3.0 2.1 2 0 0 2 2 2 0 Dynactin p62 family Zn-ribbon_8 PF09723.10 KFP05167.1 - 4.2 7.6 22.8 0.2 11.8 3.3 3.8 4 0 0 4 4 4 0 Zinc ribbon domain TNFR_c6 PF00020.18 KFP05167.1 - 5.5 7.5 19.8 0.47 10.9 0.6 4.3 3 1 2 5 5 5 0 TNFR/NGFR cysteine-rich region zf-C2H2_12 PF18658.1 KFP05167.1 - 8.4 6.0 9.2 3.4 7.3 1.6 2.9 3 0 0 3 3 3 0 Zinc-finger C2H2-type C2 PF00168.30 KFP05168.1 - 2.5e-55 185.1 0.2 2e-28 98.7 0.0 2.3 2 0 0 2 2 2 2 C2 domain MAP17 PF15807.5 KFP05168.1 - 9.2e-06 25.9 0.1 2.4e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 CEP76-C2 PF15627.6 KFP05168.1 - 2.8e-05 23.7 0.0 0.097 12.2 0.0 2.4 1 1 1 2 2 2 2 CEP76 C2 domain DOCK-C2 PF14429.6 KFP05168.1 - 0.00072 19.4 0.1 0.77 9.5 0.0 2.4 2 0 0 2 2 2 2 C2 domain in Dock180 and Zizimin proteins PI3K_C2 PF00792.24 KFP05168.1 - 0.00076 19.4 0.0 0.48 10.3 0.0 2.7 2 0 0 2 2 2 2 Phosphoinositide 3-kinase C2 TMEM52 PF14979.6 KFP05168.1 - 0.00092 19.2 2.3 0.0017 18.3 2.3 1.4 1 0 0 1 1 1 1 Transmembrane 52 FAM176 PF14851.6 KFP05168.1 - 0.0037 16.9 0.5 0.0072 16.0 0.5 1.4 1 0 0 1 1 1 1 FAM176 family EphA2_TM PF14575.6 KFP05168.1 - 0.0075 17.1 0.0 0.018 15.9 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Comm PF15957.5 KFP05168.1 - 0.02 15.2 0.0 0.044 14.1 0.0 1.5 1 0 0 1 1 1 0 Commissureless Transglut_C PF00927.22 KFP05168.1 - 0.039 14.1 0.8 6.9 6.9 0.1 2.4 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain Peptidase_M1 PF01433.20 KFP05169.1 - 2.2e-50 171.2 0.0 3.9e-50 170.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KFP05169.1 - 9.2e-32 109.5 0.3 1.5e-31 108.8 0.3 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KFP05169.1 - 7.3e-13 49.1 0.9 1.2e-12 48.4 0.9 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 KFP05169.1 - 0.034 13.8 0.6 0.12 12.1 0.0 2.1 3 0 0 3 3 3 0 Peptidase MA superfamily Kelch_3 PF13415.6 KFP05170.1 - 6.7e-39 131.5 2.9 9.5e-06 25.8 0.1 8.1 8 0 0 8 8 8 7 Galactose oxidase, central domain BTB PF00651.31 KFP05170.1 - 1.2e-33 115.7 5.8 5.5e-21 74.9 0.0 4.8 2 2 2 4 4 4 3 BTB/POZ domain Kelch_1 PF01344.25 KFP05170.1 - 2e-32 110.5 2.4 1.9e-08 33.8 0.0 5.3 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 KFP05170.1 - 4.8e-32 109.7 3.7 1.3e-08 34.7 0.0 5.5 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP05170.1 - 8.3e-31 105.5 4.6 4.5e-07 29.7 0.3 5.4 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 KFP05170.1 - 4.9e-26 90.1 5.3 4.2e-09 36.4 0.0 5.4 4 1 1 5 5 5 5 Kelch motif Kelch_2 PF07646.15 KFP05170.1 - 2.3e-19 68.5 2.0 1.8e-06 27.7 0.0 5.3 5 0 0 5 5 5 3 Kelch motif BACK PF07707.15 KFP05170.1 - 0.0025 17.9 12.7 0.0057 16.7 1.1 4.6 5 0 0 5 5 5 1 BTB And C-terminal Kelch RAG2 PF03089.14 KFP05170.1 - 0.0032 16.5 0.0 0.026 13.5 0.0 2.2 2 0 0 2 2 2 1 Recombination activating protein 2 PLU-1 PF08429.11 KFP05171.1 - 6e-94 315.0 11.0 3.8e-90 302.5 3.4 3.9 4 0 0 4 4 4 3 PLU-1-like protein JmjC PF02373.22 KFP05171.1 - 7e-45 152.1 0.7 1.6e-44 150.9 0.7 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 KFP05171.1 - 3.8e-25 87.5 37.7 1.1e-11 44.4 4.1 4.2 4 0 0 4 4 4 3 PHD-finger ARID PF01388.21 KFP05171.1 - 1.2e-17 64.3 0.0 3e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.16 KFP05171.1 - 5.6e-14 52.3 11.4 5.6e-14 52.3 11.4 2.9 2 0 0 2 2 2 1 C5HC2 zinc finger PHD_2 PF13831.6 KFP05171.1 - 0.088 12.4 28.3 0.24 11.0 2.7 4.1 4 0 0 4 4 4 0 PHD-finger Lipoprotein_20 PF13942.6 KFP05171.1 - 0.17 11.8 0.0 0.17 11.8 0.0 2.6 3 0 0 3 3 3 0 YfhG lipoprotein zf-PHD-like PF15446.6 KFP05171.1 - 3.6 7.2 16.9 0.18 11.4 0.4 4.1 4 0 0 4 4 4 0 PHD/FYVE-zinc-finger like domain Tubulin PF00091.25 KFP05172.1 - 1.7e-68 230.8 0.0 2.2e-68 230.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFP05172.1 - 3.4e-48 163.0 0.0 6.2e-48 162.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFP05172.1 - 0.0017 18.1 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain hNIFK_binding PF12196.8 KFP05173.1 - 0.087 12.3 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK Trypsin PF00089.26 KFP05174.1 - 4.1e-68 229.5 0.3 4.6e-68 229.3 0.3 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFP05174.1 - 5.7e-05 24.1 0.1 8.7e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFP05174.1 - 0.0012 19.2 1.1 0.0014 19.0 0.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) DUF316 PF03761.15 KFP05174.1 - 0.0029 17.2 0.0 0.68 9.5 0.0 2.2 1 1 0 2 2 2 2 Chymotrypsin family Peptidase-S1 Ion_trans PF00520.31 KFP05175.1 - 7.6e-250 824.4 82.4 5.5e-70 235.4 4.5 4.1 4 0 0 4 4 4 4 Ion transport protein Ca_chan_IQ PF08763.11 KFP05175.1 - 3.1e-29 101.0 0.1 6.9e-29 99.9 0.1 1.6 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain GPHH PF16905.5 KFP05175.1 - 1.4e-28 98.4 0.1 4.4e-28 96.8 0.1 1.9 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 KFP05175.1 - 3.8e-10 39.0 33.4 5.4e-09 35.2 10.8 8.7 7 3 1 8 8 8 3 Polycystin cation channel SieB PF14163.6 KFP05175.1 - 0.078 12.5 4.9 1.5 8.3 0.1 3.6 3 0 0 3 3 3 0 Super-infection exclusion protein B DUF5305 PF17231.2 KFP05175.1 - 0.14 11.5 0.1 2.5 7.4 0.0 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Kinesin PF00225.23 KFP05176.1 - 3.4e-103 345.1 0.0 3.4e-103 345.1 0.0 2.4 2 0 0 2 2 2 1 Kinesin motor domain WD40 PF00400.32 KFP05176.1 - 4.3e-27 93.8 7.4 0.0013 19.5 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat Microtub_bd PF16796.5 KFP05176.1 - 4.9e-20 72.0 0.0 1.9e-19 70.1 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding Nup160 PF11715.8 KFP05176.1 - 0.00028 19.7 1.8 5.6 5.5 0.0 4.9 3 1 2 5 5 5 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KFP05176.1 - 0.0085 16.4 0.0 22 5.5 0.0 4.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4094 PF13334.6 KFP05176.1 - 0.092 13.2 0.1 0.092 13.2 0.1 5.4 4 1 2 6 6 6 0 Domain of unknown function (DUF4094) Ets PF00178.22 KFP05177.1 - 8.2e-31 106.3 1.3 1.6e-30 105.4 1.3 1.5 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 KFP05177.1 - 4.8e-18 64.9 0.1 2.3e-17 62.7 0.1 2.1 3 0 0 3 3 3 1 Sterile alpha motif (SAM)/Pointed domain AT_hook PF02178.19 KFP05177.1 - 0.32 11.0 6.0 0.83 9.7 6.0 1.7 1 0 0 1 1 1 0 AT hook motif 7tm_1 PF00001.21 KFP05178.1 - 1.2e-23 83.8 14.7 1.8e-23 83.2 14.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PDR_CDR PF06422.12 KFP05178.1 - 0.06 13.3 4.3 0.24 11.3 0.0 2.5 2 0 0 2 2 2 0 CDR ABC transporter Arf PF00025.21 KFP05179.1 - 2.5e-39 134.5 0.0 3e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFP05179.1 - 6.9e-14 51.8 0.0 7.6e-14 51.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP05179.1 - 7.7e-11 42.3 0.0 1.2e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KFP05179.1 - 2.3e-06 27.1 0.0 2.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KFP05179.1 - 1.9e-05 24.0 0.0 2.3e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.23 KFP05179.1 - 0.0011 19.1 0.0 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFP05179.1 - 0.0028 17.1 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Y_phosphatase PF00102.27 KFP05180.1 - 1e-72 244.6 0.0 1.3e-72 244.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFP05180.1 - 5e-05 23.1 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP05180.1 - 0.0045 17.0 0.0 0.0087 16.1 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFP05180.1 - 0.13 12.3 0.1 0.61 10.2 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate LRR_8 PF13855.6 KFP05181.1 - 1.3e-77 255.5 40.7 6.3e-16 57.9 1.0 7.3 3 2 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 KFP05181.1 - 3.1e-37 126.0 28.2 5.3e-06 26.7 0.3 9.5 5 2 5 10 10 10 10 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP05181.1 - 1.7e-21 76.5 0.0 1.4e-08 34.8 0.0 3.9 1 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP05181.1 - 9.9e-16 57.7 9.7 0.0013 18.3 0.3 4.7 1 1 4 5 5 5 5 Leucine-rich repeat LRR_1 PF00560.33 KFP05181.1 - 4.1e-08 32.7 28.1 5.7 7.9 0.0 11.7 11 2 0 11 11 11 4 Leucine Rich Repeat 7tm_1 PF00001.21 KFP05181.1 - 0.00011 21.7 12.5 0.00026 20.4 12.5 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_6 PF13516.6 KFP05181.1 - 0.019 15.0 34.3 0.17 12.0 0.0 9.1 12 0 0 12 12 12 0 Leucine Rich repeat LRR_8 PF13855.6 KFP05183.1 - 3.2e-59 196.6 75.9 1.9e-14 53.2 6.7 6.6 1 1 6 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 KFP05183.1 - 1.1e-23 82.9 45.0 0.00044 20.6 3.7 8.0 2 1 9 11 11 11 11 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP05183.1 - 1.6e-17 63.7 0.0 1e-08 35.2 0.0 2.8 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP05183.1 - 4.6e-15 55.6 17.8 5.4e-05 22.8 2.0 4.6 1 1 4 5 5 5 5 Leucine-rich repeat I-set PF07679.16 KFP05183.1 - 1.1e-13 51.1 0.0 2.1e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP05183.1 - 5.8e-10 39.6 0.0 1.3e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.33 KFP05183.1 - 3.4e-06 26.9 31.8 0.3 11.8 0.1 10.6 11 0 0 11 11 10 2 Leucine Rich Repeat Ig_2 PF13895.6 KFP05183.1 - 8.5e-06 26.0 0.0 1.7e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP05183.1 - 0.00037 20.6 0.0 0.00084 19.5 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP05183.1 - 0.0059 16.8 0.0 1.6 8.9 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin V-set domain LRRCT PF01463.24 KFP05183.1 - 0.044 14.3 0.2 0.23 12.1 0.2 2.4 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain Ig_6 PF18452.1 KFP05183.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain LRRNT PF01462.18 KFP05183.1 - 4.8 6.9 6.6 0.6 9.8 1.2 2.4 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain zf-C3HC4_3 PF13920.6 KFP05184.1 - 1e-10 41.3 6.4 1e-10 41.3 6.4 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RanBP PF00641.18 KFP05184.1 - 2.2e-06 26.9 8.4 2.2e-06 26.9 8.4 2.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others SWIB PF02201.18 KFP05184.1 - 5.7e-06 26.1 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DZR PF12773.7 KFP05184.1 - 0.43 10.6 17.6 2.3 8.3 2.2 3.0 2 0 0 2 2 2 0 Double zinc ribbon PI3_PI4_kinase PF00454.27 KFP05186.1 - 4.5e-56 190.5 0.6 1.5e-55 188.7 0.6 1.8 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KFP05186.1 - 7.3e-37 126.6 0.3 1.6e-36 125.5 0.3 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 KFP05186.1 - 8e-31 106.8 0.0 1.9e-30 105.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 KFP05186.1 - 1.3e-25 89.6 0.0 4.8e-25 87.8 0.1 2.0 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain C2 PF00168.30 KFP05186.1 - 1.4e-17 63.9 0.0 3.3e-17 62.6 0.0 1.7 2 0 0 2 2 2 1 C2 domain PX PF00787.24 KFP05186.1 - 0.00021 21.2 0.0 0.0031 17.5 0.0 2.6 1 1 0 1 1 1 1 PX domain DUF4135 PF13575.6 KFP05186.1 - 0.00087 18.7 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) PP1c_bdg PF10488.9 KFP05187.1 - 1.3e-121 405.5 7.3 1.5e-121 405.3 7.3 1.0 1 0 0 1 1 1 1 Phosphatase-1 catalytic subunit binding region DCA16 PF15349.6 KFP05187.1 - 0.02 14.4 1.2 0.033 13.8 1.2 1.3 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 SDA1 PF05285.12 KFP05187.1 - 0.23 10.8 9.1 0.31 10.4 9.1 1.2 1 0 0 1 1 1 0 SDA1 VEFS-Box PF09733.9 KFP05187.1 - 0.51 10.2 5.6 2.8 7.7 0.2 2.3 2 0 0 2 2 2 0 VEFS-Box of polycomb protein PH PF00169.29 KFP05188.1 - 1e-12 48.5 0.2 3.5e-12 46.8 0.2 2.0 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 KFP05188.1 - 0.00013 22.3 2.3 0.0041 17.5 2.3 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain AAA_13 PF13166.6 KFP05188.1 - 0.034 12.8 3.6 0.077 11.6 3.6 1.5 1 0 0 1 1 1 0 AAA domain PI3K_1B_p101 PF10486.9 KFP05188.1 - 0.056 11.2 4.0 0.074 10.8 3.0 1.5 1 1 1 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Got1 PF04178.12 KFP05189.1 - 7.5e-16 58.6 18.5 8.1e-16 58.5 18.5 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family Asp PF00026.23 KFP05190.1 - 1.4e-110 369.7 0.0 1.6e-110 369.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFP05190.1 - 1.2e-10 41.9 0.1 5.5e-09 36.5 0.1 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.12 KFP05190.1 - 7.5e-05 22.5 0.2 0.00015 21.6 0.2 1.5 1 0 0 1 1 1 1 A1 Propeptide TAXi_C PF14541.6 KFP05190.1 - 0.00087 19.1 0.0 0.0027 17.5 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Kelch_6 PF13964.6 KFP05190.1 - 0.13 12.6 2.3 16 6.0 0.1 2.7 2 1 0 2 2 2 0 Kelch motif Choline_kinase PF01633.20 KFP05191.1 - 1.2e-59 201.4 0.0 1.8e-59 200.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KFP05191.1 - 1.3e-11 44.9 0.0 1.9e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFP05191.1 - 0.00022 20.6 0.4 0.00061 19.2 0.4 1.7 1 1 0 1 1 1 1 Ecdysteroid kinase LSM PF01423.22 KFP05192.1 - 1.8e-17 62.8 0.2 2e-17 62.6 0.2 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KFP05192.1 - 0.0017 17.9 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Hfq protein DUF777 PF05606.11 KFP05192.1 - 0.026 14.3 0.2 0.031 14.0 0.2 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF777) Cation_ATPase_C PF00689.21 KFP05193.1 - 2.2e-44 151.4 3.4 1.3e-43 148.8 1.2 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KFP05193.1 - 2.3e-35 121.7 14.4 8.5e-27 93.8 1.8 2.9 3 0 0 3 3 3 2 E1-E2 ATPase ATP_Ca_trans_C PF12424.8 KFP05193.1 - 3.1e-27 94.8 0.1 1.2e-26 92.9 0.1 2.1 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal Cation_ATPase PF13246.6 KFP05193.1 - 2e-20 72.7 0.0 4.6e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFP05193.1 - 2e-15 56.2 0.0 8e-15 54.3 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KFP05193.1 - 3.3e-14 53.7 0.6 6.4e-13 49.5 0.6 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFP05193.1 - 1.5e-06 28.2 0.2 0.00015 21.6 0.2 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Ferlin_C PF16165.5 KFP05193.1 - 0.15 12.0 0.9 26 4.7 0.0 2.7 2 0 0 2 2 2 0 Ferlin C-terminus Trypan_PARP PF05887.11 KFP05193.1 - 2 8.4 7.1 28 4.7 0.3 3.0 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) LRR_8 PF13855.6 KFP05194.1 - 1.6e-32 111.0 37.3 3.1e-12 46.1 9.1 7.4 3 3 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 KFP05194.1 - 1.4e-24 85.7 36.8 1.2e-06 28.8 2.3 7.3 5 2 2 7 7 7 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP05194.1 - 3e-06 26.9 16.1 0.0034 16.9 4.5 4.2 1 1 3 4 4 4 3 Leucine-rich repeat LRRNT PF01462.18 KFP05194.1 - 3.5e-06 26.5 4.4 3.5e-06 26.5 4.4 3.2 4 0 0 4 4 4 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KFP05194.1 - 2.5e-05 24.2 33.2 0.57 10.9 0.1 10.5 9 2 0 9 9 9 1 Leucine Rich Repeat LRR_6 PF13516.6 KFP05194.1 - 0.0018 18.2 22.2 8 6.8 0.0 7.7 8 0 0 8 8 8 3 Leucine Rich repeat LRR_5 PF13306.6 KFP05194.1 - 0.0029 17.6 0.9 0.037 14.0 0.3 2.5 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) FNIP PF05725.12 KFP05194.1 - 0.022 14.9 8.7 5.2 7.3 0.1 4.3 2 2 2 4 4 4 0 FNIP Repeat LRR_8 PF13855.6 KFP05195.1 - 2e-30 104.3 23.2 8.7e-10 38.2 0.3 6.2 2 2 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFP05195.1 - 2.1e-23 82.0 25.2 1.8e-06 28.1 0.7 7.1 1 1 6 8 8 8 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP05195.1 - 2.7e-11 43.3 7.2 9.6e-05 22.0 0.3 4.2 1 1 3 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 KFP05195.1 - 4.6e-11 41.7 18.9 0.29 11.8 0.0 9.6 9 1 0 9 9 9 4 Leucine Rich Repeat LRR_6 PF13516.6 KFP05195.1 - 1.4e-08 34.1 17.3 0.095 12.8 0.0 7.9 8 0 0 8 8 8 4 Leucine Rich repeat LRRNT PF01462.18 KFP05195.1 - 3.4e-07 29.8 9.2 7.9e-07 28.6 2.0 3.3 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.6 KFP05195.1 - 1.6e-06 28.1 3.9 3.9e-05 23.6 0.0 2.7 2 2 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) BTG PF07742.12 KFP05196.1 - 4.6e-36 123.2 0.0 5.4e-36 123.0 0.0 1.1 1 0 0 1 1 1 1 BTG family Glyco_hydro_18 PF00704.28 KFP05197.1 - 5.3e-97 325.3 0.2 6.2e-97 325.1 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 KFP05197.1 - 1.8e-10 40.8 7.2 3.6e-10 39.8 7.2 1.6 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Kelch_1 PF01344.25 KFP05197.1 - 0.052 13.1 0.0 12 5.6 0.0 2.7 2 0 0 2 2 2 0 Kelch motif Bromo_TP PF07524.13 KFP05199.1 - 1.3e-30 105.2 0.7 3.3e-30 103.9 0.2 1.8 2 0 0 2 2 2 1 Bromodomain associated TAF8_C PF10406.9 KFP05199.1 - 1e-22 80.4 2.5 3.2e-22 78.8 1.3 2.3 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term TFIID-31kDa PF02291.15 KFP05199.1 - 2.8e-05 24.2 0.0 4.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP_like PF17027.5 KFP05199.1 - 0.00027 21.1 0.0 0.00053 20.1 0.0 1.5 1 0 0 1 1 1 1 Histone-fold protein DUF3090 PF11290.8 KFP05199.1 - 0.0051 16.6 0.4 0.018 14.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3090) CENP-S PF15630.6 KFP05199.1 - 0.02 15.3 0.0 0.052 13.9 0.0 1.7 1 1 0 1 1 1 0 CENP-S protein CBFD_NFYB_HMF PF00808.23 KFP05199.1 - 0.046 14.0 0.1 0.095 13.0 0.1 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KFP05199.1 - 0.08 13.1 0.0 0.22 11.7 0.0 1.8 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T histone fold Type2_restr_D3 PF16902.5 KFP05199.1 - 0.085 12.8 0.2 47 4.0 0.0 3.5 4 0 0 4 4 4 0 Type-2 restriction enzyme D3 domain Cyclin_N PF00134.23 KFP05200.1 - 1.2e-27 96.2 0.4 1.8e-27 95.6 0.4 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP05200.1 - 2.6e-19 69.4 0.7 8.4e-19 67.8 0.2 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain K-cyclin_vir_C PF09080.10 KFP05200.1 - 0.00079 19.8 0.4 0.0013 19.1 0.4 1.3 1 0 0 1 1 1 1 K cyclin, C terminal Herp-Cyclin PF09241.10 KFP05200.1 - 0.0059 17.2 0.1 0.01 16.5 0.1 1.4 1 0 0 1 1 1 1 Herpesviridae viral cyclin PMEI PF04043.15 KFP05200.1 - 0.027 14.8 0.5 0.044 14.1 0.5 1.4 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Bystin PF05291.11 KFP05201.1 - 3.6e-141 469.6 0.6 4.6e-141 469.2 0.6 1.0 1 0 0 1 1 1 1 Bystin Med20 PF08612.11 KFP05202.1 - 4.6e-41 140.6 0.0 5.2e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex FXa_inhibition PF14670.6 KFP05203.1 - 4.2e-57 190.1 187.9 1.1e-10 41.6 8.5 12.9 12 2 0 12 12 12 9 Coagulation Factor Xa inhibitory site Ephrin_rec_like PF07699.13 KFP05203.1 - 4.2e-39 132.1 44.4 2.6e-14 52.7 6.4 6.7 5 1 1 6 6 6 3 Putative ephrin-receptor like cEGF PF12662.7 KFP05203.1 - 1.5e-35 120.7 106.4 2.5e-08 33.7 0.1 12.3 13 1 0 13 13 13 8 Complement Clr-like EGF-like EGF_CA PF07645.15 KFP05203.1 - 4.7e-28 97.1 95.8 5.6e-09 36.1 10.1 11.8 13 1 0 13 13 13 6 Calcium-binding EGF domain EGF_3 PF12947.7 KFP05203.1 - 2.8e-20 72.2 145.1 3.6e-10 39.9 11.7 11.8 11 1 0 11 11 11 8 EGF domain CUB PF00431.20 KFP05203.1 - 2.1e-18 66.6 0.0 6.4e-18 65.1 0.0 1.9 1 0 0 1 1 1 1 CUB domain EGF PF00008.27 KFP05203.1 - 1.9e-17 63.3 131.3 1.7e-05 25.0 7.2 11.9 10 0 0 10 10 10 8 EGF-like domain hEGF PF12661.7 KFP05203.1 - 0.001 19.6 1.4 0.001 19.6 1.4 12.9 12 0 0 12 12 12 5 Human growth factor-like EGF PID PF00640.23 KFP05204.1 - 2.2e-19 69.9 0.9 4.2e-19 69.0 0.9 1.5 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFP05204.1 - 0.00037 20.6 0.0 0.00056 20.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.6 KFP05204.1 - 0.003 17.5 0.0 0.0036 17.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Coq4 PF05019.13 KFP05204.1 - 0.084 12.2 0.0 0.16 11.3 0.0 1.5 2 0 0 2 2 2 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Ank_2 PF12796.7 KFP05205.1 - 4.3e-40 136.2 8.2 4.5e-18 65.6 0.6 3.8 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP05205.1 - 5.4e-38 128.6 16.7 8e-11 42.0 0.0 6.7 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP05205.1 - 3.7e-36 123.0 5.1 2.9e-08 34.1 0.1 5.4 3 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KFP05205.1 - 2.3e-35 119.5 15.7 1.6e-05 25.1 0.0 6.9 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 KFP05205.1 - 5.1e-35 115.5 3.3 5.5e-05 23.3 0.0 6.9 6 0 0 6 6 6 6 Ankyrin repeat SAM_1 PF00536.30 KFP05205.1 - 1.5e-22 79.8 0.1 7.4e-13 48.7 0.0 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP05205.1 - 2.3e-20 72.4 0.3 3.4e-13 49.5 0.1 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) TAFII28 PF04719.14 KFP05206.1 - 1.3e-39 134.1 0.0 2.3e-39 133.3 0.0 1.4 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.23 KFP05206.1 - 2.5e-06 27.7 0.0 5.5e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-X PF09415.10 KFP05206.1 - 0.029 14.7 1.6 8.4 6.8 0.4 2.7 3 0 0 3 3 3 0 CENP-S associating Centromere protein X Chorein_N PF12624.7 KFP05207.1 - 1.1e-15 57.8 0.1 6.3e-14 52.1 0.0 3.0 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 zf-U1 PF06220.12 KFP05208.1 - 1.9e-20 72.3 8.3 2.5e-20 71.9 8.3 1.2 1 0 0 1 1 1 1 U1 zinc finger Phage_int_SAM_3 PF14659.6 KFP05208.1 - 0.12 12.6 0.1 0.7 10.2 0.1 1.9 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain zf-C2H2_jaz PF12171.8 KFP05208.1 - 2.1 8.7 9.9 25 5.3 9.9 2.1 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP05208.1 - 2.5 8.6 5.1 24 5.5 5.1 2.1 1 1 0 1 1 1 0 Zinc-finger of C2H2 type N_BRCA1_IG PF16158.5 KFP05209.1 - 1.7e-34 118.6 0.1 3.1e-34 117.8 0.1 1.4 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene CARDB PF07705.11 KFP05209.1 - 0.073 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 CARDB Ets PF00178.22 KFP05210.1 - 1.8e-34 118.0 1.0 3.6e-34 117.1 1.0 1.5 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 KFP05210.1 - 4.6e-25 87.4 0.1 8.6e-25 86.5 0.1 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_3 PF18016.1 KFP05210.1 - 0.072 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) FCH PF00611.23 KFP05211.1 - 4.6e-17 62.1 0.5 4.6e-17 62.1 0.5 3.0 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 KFP05211.1 - 2.7e-15 56.0 0.4 6e-15 54.8 0.4 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP05211.1 - 1e-14 53.8 0.1 2e-14 52.9 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP05211.1 - 2.3e-07 30.4 0.0 4.1e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain KAP_NTPase PF07693.14 KFP05211.1 - 0.016 14.5 0.7 0.023 14.0 0.7 1.3 1 0 0 1 1 1 0 KAP family P-loop domain PAP_central PF04928.17 KFP05211.1 - 0.35 9.8 3.6 0.74 8.7 3.6 1.5 1 0 0 1 1 1 0 Poly(A) polymerase central domain EzrA PF06160.12 KFP05211.1 - 0.54 8.4 19.7 0.64 8.1 18.7 1.5 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA PilJ PF13675.6 KFP05211.1 - 0.92 9.6 5.6 0.5 10.4 0.2 2.7 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Tho2 PF11262.8 KFP05211.1 - 2.6 7.2 18.0 0.49 9.5 11.4 2.4 1 1 2 3 3 3 0 Transcription factor/nuclear export subunit protein 2 Laminin_II PF06009.12 KFP05211.1 - 3.6 7.6 9.3 0.35 10.9 3.5 2.2 2 1 1 3 3 3 0 Laminin Domain II DUF2935 PF11155.8 KFP05211.1 - 4.2 7.7 7.6 2.7e+02 1.9 7.6 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Phlebovirus_NSM PF07246.11 KFP05211.1 - 4.6 6.5 12.1 7 5.9 11.4 1.6 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M ApoO PF09769.9 KFP05211.1 - 6.5 6.7 4.9 4.4 7.3 2.2 2.1 1 1 0 2 2 2 0 Apolipoprotein O LOH1CR12 PF10158.9 KFP05211.1 - 6.7 6.7 9.5 3.7 7.6 5.1 2.4 1 1 2 3 3 3 0 Tumour suppressor protein NUDIX PF00293.28 KFP05213.1 - 1.4e-16 60.7 0.3 1.7e-16 60.5 0.3 1.1 1 0 0 1 1 1 1 NUDIX domain ANF_receptor PF01094.28 KFP05214.1 - 1.3e-107 360.0 0.0 1.7e-107 359.6 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 KFP05214.1 - 1.3e-57 195.3 17.2 1.8e-57 194.8 17.2 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 KFP05214.1 - 3e-13 49.5 12.3 6.3e-13 48.5 12.3 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.6 KFP05214.1 - 6.7e-11 42.4 0.0 5.1e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 Periplasmic binding protein Haem_degrading PF03928.14 KFP05214.1 - 0.016 15.3 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 Haem-degrading DUF2318 PF10080.9 KFP05214.1 - 0.027 14.6 1.4 0.068 13.3 1.4 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) 7tm_1 PF00001.21 KFP05215.1 - 1.4e-45 155.7 10.5 1.9e-45 155.2 10.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Rhodopsin_N PF10413.9 KFP05215.1 - 1.1e-25 89.1 3.3 2.6e-25 87.9 3.3 1.7 1 0 0 1 1 1 1 Amino terminal of the G-protein receptor rhodopsin 7TM_GPCR_Srw PF10324.9 KFP05215.1 - 1.7e-11 44.0 11.6 1.2e-10 41.3 11.6 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 KFP05215.1 - 7.4e-08 32.1 12.9 1.2e-07 31.4 12.9 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 KFP05215.1 - 4.7e-06 26.2 13.7 7.1e-06 25.6 13.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv DUF2852 PF11014.8 KFP05215.1 - 0.21 11.8 2.1 0.9 9.7 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2852) TAS2R PF05296.13 KFP05215.1 - 0.4 9.8 11.5 2.1 7.4 1.1 2.2 2 0 0 2 2 2 0 Taste receptor protein (TAS2R) 7tm_4 PF13853.6 KFP05215.1 - 0.47 10.1 15.2 29 4.3 15.2 2.9 1 1 0 1 1 1 0 Olfactory receptor DUF4407 PF14362.6 KFP05215.1 - 1.2 8.4 5.6 2.1 7.7 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4079 PF13301.6 KFP05215.1 - 1.8 8.7 7.0 0.08 13.1 0.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) 60KD_IMP PF02096.20 KFP05215.1 - 3.8 7.4 7.6 30 4.4 7.6 2.5 1 1 0 1 1 1 0 60Kd inner membrane protein MSC PF09402.10 KFP05216.1 - 4.8e-20 72.3 0.4 6.6e-20 71.8 0.4 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain Bcl-2 PF00452.19 KFP05217.1 - 5.4e-26 91.2 0.3 1.1e-25 90.2 0.0 1.6 2 0 0 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family Bcl-2_3 PF15286.6 KFP05217.1 - 0.091 13.4 0.0 0.17 12.6 0.0 1.6 1 1 0 1 1 1 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like TspO_MBR PF03073.15 KFP05218.1 - 1.2e-47 161.4 9.3 1.3e-47 161.2 9.3 1.0 1 0 0 1 1 1 1 TspO/MBR family Macro PF01661.21 KFP05219.1 - 2.8e-08 33.8 0.0 4.3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Macro domain Il2rg PF15874.5 KFP05219.1 - 0.073 13.3 0.0 0.095 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative Interleukin 2 receptor, gamma chain CBFB_NFYA PF02045.15 KFP05220.1 - 2.1e-27 95.5 8.7 3.4e-27 94.8 8.7 1.3 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B V-set PF07686.17 KFP05221.1 - 2.9e-12 46.7 0.3 4.9e-12 46.0 0.3 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain Herpes_gE PF02480.16 KFP05221.1 - 0.0049 15.7 0.0 0.011 14.5 0.0 1.5 1 1 0 1 1 1 1 Alphaherpesvirus glycoprotein E FSAP_sig_propep PF03032.15 KFP05221.1 - 0.0089 16.0 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Frog skin active peptide family signal and propeptide Sterol-sensing PF12349.8 KFP05221.1 - 0.014 15.2 0.1 0.022 14.6 0.1 1.3 1 0 0 1 1 1 0 Sterol-sensing domain of SREBP cleavage-activation Ig_3 PF13927.6 KFP05221.1 - 0.042 14.5 0.5 0.13 12.9 0.5 1.9 1 1 0 1 1 1 0 Immunoglobulin domain Gemini_mov PF01708.16 KFP05221.1 - 0.087 12.6 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Geminivirus putative movement protein ig PF00047.25 KFP05221.1 - 0.14 12.4 0.1 0.14 12.4 0.1 1.9 2 1 0 2 2 2 0 Immunoglobulin domain Egh16-like PF11327.8 KFP05221.1 - 0.18 12.3 0.0 0.39 11.1 0.0 1.3 1 1 0 1 1 1 0 Egh16-like virulence factor MDFI PF15316.6 KFP05222.1 - 1.3e-47 162.0 41.4 1.5e-47 161.9 41.4 1.1 1 0 0 1 1 1 1 MyoD family inhibitor Asp PF00026.23 KFP05223.1 - 2.2e-82 277.0 0.0 2.7e-82 276.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFP05223.1 - 5.4e-10 39.8 0.0 1.3e-08 35.3 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KFP05223.1 - 0.00028 20.7 0.0 0.00068 19.4 0.0 1.6 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal A1_Propeptide PF07966.12 KFP05223.1 - 0.003 17.4 0.2 0.0067 16.3 0.2 1.6 1 0 0 1 1 1 1 A1 Propeptide Asp PF00026.23 KFP05224.1 - 1.1e-104 350.3 0.0 1.3e-104 350.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFP05224.1 - 6.1e-12 46.1 1.3 1.5e-08 35.1 0.1 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal A1_Propeptide PF07966.12 KFP05224.1 - 9.3e-10 38.2 1.1 2e-09 37.1 1.1 1.6 1 0 0 1 1 1 1 A1 Propeptide Asp_protease_2 PF13650.6 KFP05224.1 - 2.7e-05 24.7 0.0 0.032 14.8 0.0 2.7 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KFP05224.1 - 0.00097 18.9 0.1 0.015 15.1 0.0 2.7 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KFP05224.1 - 0.069 13.7 0.0 26 5.5 0.0 2.7 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease IRS PF02174.17 KFP05225.1 - 1.8e-26 91.9 0.1 3.8e-26 90.9 0.1 1.4 1 0 0 1 1 1 1 PTB domain (IRS-1 type) LIM PF00412.22 KFP05226.1 - 2.6e-15 56.4 17.8 1.6e-07 31.4 3.6 2.4 2 0 0 2 2 2 2 LIM domain PET PF06297.14 KFP05226.1 - 3.8e-13 49.6 0.6 6.2e-13 48.9 0.6 1.4 1 0 0 1 1 1 1 PET Domain GETHR PF05671.11 KFP05227.1 - 0.34 10.3 17.0 5.3 6.5 2.9 3.2 1 1 3 4 4 4 0 GETHR pentapeptide repeat (5 copies) UCH PF00443.29 KFP05228.1 - 1.3e-57 195.2 0.2 1.3e-57 195.2 0.2 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFP05228.1 - 9.9e-22 77.0 7.5 9.9e-22 77.0 7.5 2.9 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KFP05228.1 - 1.2e-15 57.9 0.8 1.2e-15 57.9 0.8 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 KFP05228.1 - 0.03 14.1 0.4 0.03 14.1 0.4 2.5 2 0 0 2 2 2 0 Variant UBP zinc finger Stc1 PF12898.7 KFP05228.1 - 0.28 11.7 0.1 0.28 11.7 0.1 3.0 3 0 0 3 3 3 0 Stc1 domain ArfGap PF01412.18 KFP05228.1 - 7.1 6.7 9.6 0.3 11.2 2.4 2.4 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf Yae1_N PF09811.9 KFP05229.1 - 0.025 14.3 25.0 4.1e+03 -2.4 25.0 3.1 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Ribosomal_L1 PF00687.21 KFP05230.1 - 6.3e-45 153.4 5.5 7.6e-45 153.2 5.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family TetR PF13972.6 KFP05230.1 - 0.069 12.9 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Bacterial transcriptional repressor DUF3671 PF12420.8 KFP05230.1 - 0.07 13.2 3.0 0.13 12.4 2.9 1.5 1 1 0 1 1 1 0 Protein of unknown function zf-H2C2_2 PF13465.6 KFP05231.1 - 5.2e-22 77.2 15.2 3.6e-09 36.6 0.4 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFP05231.1 - 1.4e-13 50.5 12.0 9e-08 32.2 0.5 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP05231.1 - 2e-09 37.5 10.4 6.9e-05 23.3 0.3 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP05231.1 - 2.2e-05 24.6 0.7 0.01 16.1 0.2 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 KFP05231.1 - 4.5e-05 24.0 0.9 4.5e-05 24.0 0.9 1.7 1 1 1 2 2 2 1 TRAF-type zinc finger zf-C2H2_aberr PF17017.5 KFP05231.1 - 0.0058 16.8 1.8 0.024 14.8 0.5 2.1 1 1 0 1 1 1 1 Aberrant zinc-finger zf-Di19 PF05605.12 KFP05231.1 - 0.0081 16.4 3.9 0.67 10.3 0.7 2.2 1 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding Ogr_Delta PF04606.12 KFP05231.1 - 0.034 14.1 2.0 1.6 8.8 0.7 2.7 1 1 2 3 3 3 0 Ogr/Delta-like zinc finger DUF3268 PF11672.8 KFP05231.1 - 0.11 12.9 0.4 0.17 12.2 0.1 1.5 2 0 0 2 2 2 0 zinc-finger-containing domain IBR PF01485.21 KFP05231.1 - 0.17 12.1 6.7 0.35 11.1 1.0 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-UBP PF02148.19 KFP05231.1 - 0.2 12.0 2.6 0.87 10.0 0.1 2.3 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein CCAP PF11105.8 KFP05231.1 - 0.29 11.1 0.9 0.3 11.1 0.9 1.2 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a zf-H2C2_5 PF13909.6 KFP05231.1 - 0.31 10.8 15.7 0.085 12.6 2.6 4.0 3 2 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFP05231.1 - 0.83 9.7 4.1 2.4 8.3 0.9 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFP05231.1 - 3.6 7.6 9.5 8.2 6.5 0.9 3.5 3 2 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 KFP05232.1 - 1.2e-07 31.8 10.8 0.0013 19.1 2.4 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP05232.1 - 0.00041 21.0 12.9 0.078 13.9 1.4 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KFP05232.1 - 0.017 15.8 4.3 0.036 14.7 0.4 2.1 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 KFP05232.1 - 0.2 11.8 5.9 0.088 12.9 2.0 1.9 1 1 1 2 2 2 0 Aberrant zinc-finger zf-H2C2_2 PF13465.6 KFP05232.1 - 0.2 12.1 17.6 1.5 9.3 7.2 3.0 3 0 0 3 3 3 0 Zinc-finger double domain DUF629 PF04780.12 KFP05232.1 - 1.4 7.4 6.2 2.6 6.5 1.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) PH PF00169.29 KFP05233.1 - 3.3e-20 72.6 1.1 1e-19 71.0 1.1 1.9 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 KFP05233.1 - 1e-06 28.8 0.2 1e-06 28.8 0.2 2.4 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KFP05233.1 - 2.8e-06 27.7 5.5 2.8e-06 27.7 5.5 3.4 2 2 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 KFP05233.1 - 0.00012 22.3 0.2 0.00052 20.2 0.1 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_2 PF08458.10 KFP05233.1 - 0.0007 19.9 4.8 0.0051 17.1 0.2 3.4 2 1 0 2 2 2 1 Plant pleckstrin homology-like region EF-hand_6 PF13405.6 KFP05233.1 - 0.018 14.9 0.0 0.09 12.8 0.0 2.3 1 0 0 1 1 1 0 EF-hand domain zf-C4 PF00105.18 KFP05235.1 - 4.6e-09 36.6 5.0 7.2e-09 36.0 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Zn_Tnp_IS91 PF14319.6 KFP05235.1 - 0.11 12.6 1.4 0.14 12.2 1.4 1.3 1 0 0 1 1 1 0 Transposase zinc-binding domain FA_FANCE PF11510.8 KFP05236.1 - 6.6e-65 219.1 15.3 9.7e-65 218.5 15.3 1.2 1 0 0 1 1 1 1 Fanconi Anaemia group E protein FANCE MRVI1 PF05781.12 KFP05237.1 - 1.7e-52 178.8 3.5 2.3e-52 178.4 3.5 1.0 1 0 0 1 1 1 1 MRVI1 protein Not3 PF04065.15 KFP05237.1 - 0.0056 16.1 1.0 0.0074 15.7 1.0 1.1 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component DUF3826 PF12875.7 KFP05237.1 - 0.04 14.1 0.8 0.056 13.6 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3826) Gag_p17 PF00540.18 KFP05237.1 - 0.27 11.2 2.3 0.39 10.7 1.1 1.7 1 1 1 2 2 2 0 gag gene protein p17 (matrix protein) FapA PF03961.13 KFP05237.1 - 0.6 8.7 2.6 0.74 8.4 2.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A CENP-Q PF13094.6 KFP05237.1 - 0.99 9.6 16.0 1.6 8.9 8.2 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit P4Ha_N PF08336.11 KFP05237.1 - 2 8.4 7.1 1.5 8.9 3.8 2.0 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Plasmid_RAQPRD PF09686.10 KFP05237.1 - 3.2 8.0 9.5 15 5.9 6.0 2.6 1 1 1 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Exo_endo_phos PF03372.23 KFP05239.1 - 6.1e-13 48.8 0.0 1.2e-12 47.8 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YBD PF17725.1 KFP05240.1 - 4.8e-96 320.6 0.5 6.2e-96 320.2 0.5 1.1 1 0 0 1 1 1 1 YAP binding domain TEA PF01285.18 KFP05240.1 - 4e-27 94.1 0.0 8.3e-27 93.1 0.0 1.5 1 0 0 1 1 1 1 TEA/ATTS domain Rotamase_2 PF13145.6 KFP05240.1 - 0.12 13.2 0.0 0.24 12.2 0.0 1.4 1 0 0 1 1 1 0 PPIC-type PPIASE domain Tub PF01167.18 KFP05241.1 - 1.6e-95 319.4 0.0 1.9e-95 319.2 0.0 1.0 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.8 KFP05241.1 - 0.03 13.9 0.1 0.17 11.4 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3527) FKBP_C PF00254.28 KFP05242.1 - 2.4e-46 156.0 0.0 4.7e-28 97.4 0.0 2.3 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 KFP05242.1 - 2.4e-16 58.8 8.4 1.1e-08 34.5 0.9 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFP05242.1 - 8e-11 41.2 6.4 5e-05 23.1 0.5 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP05242.1 - 2.5e-10 39.7 4.7 2.3e-05 24.2 0.4 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFP05242.1 - 1.8e-06 28.1 0.9 0.00047 20.4 0.6 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP05242.1 - 2e-06 28.2 0.4 0.00085 19.8 0.3 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFP05242.1 - 8.8e-06 25.4 0.3 4.5e-05 23.2 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFP05242.1 - 1.2e-05 25.7 1.3 0.048 14.3 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFP05242.1 - 3.1e-05 23.9 1.6 0.005 16.9 0.1 2.5 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 KFP05242.1 - 8.6e-05 22.1 1.7 0.024 14.3 0.0 3.3 2 1 1 3 3 3 1 TPR repeat TPR_9 PF13371.6 KFP05242.1 - 0.0011 19.1 0.1 0.0049 17.0 0.0 2.1 3 0 0 3 3 3 1 Tetratricopeptide repeat FKBP_N_2 PF18023.1 KFP05242.1 - 0.004 17.2 0.1 0.078 13.1 0.0 3.0 3 1 0 3 3 3 1 BDBT FKBP like N-terminal DUF3856 PF12968.7 KFP05242.1 - 0.041 13.9 0.2 0.075 13.1 0.2 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) PknG_TPR PF16918.5 KFP05242.1 - 0.046 12.5 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat TPR_16 PF13432.6 KFP05242.1 - 0.059 14.0 0.1 0.32 11.7 0.0 2.2 3 0 0 3 3 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP05242.1 - 0.081 13.2 5.5 0.15 12.3 1.0 2.7 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KFP05242.1 - 0.67 10.5 2.6 96 3.7 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Colipase_C PF02740.14 KFP05243.1 - 7.9e-27 93.2 4.8 1.4e-26 92.4 4.8 1.4 1 0 0 1 1 1 1 Colipase, C-terminal domain Colipase PF01114.18 KFP05243.1 - 2.8e-16 58.9 7.7 5.5e-16 57.9 7.7 1.5 1 0 0 1 1 1 1 Colipase, N-terminal domain Colipase-like PF15083.6 KFP05243.1 - 0.001 19.2 6.5 0.0012 18.9 6.5 1.1 1 0 0 1 1 1 1 Colipase-like L_HMGIC_fpl PF10242.9 KFP05244.1 - 1.4e-60 204.6 6.7 1.6e-60 204.4 6.7 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.20 KFP05244.1 - 0.00045 20.1 6.1 0.00066 19.6 6.1 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Pkinase PF00069.25 KFP05245.1 - 1.5e-42 145.8 0.1 3.1e-22 79.2 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFP05245.1 - 8.2e-14 51.5 0.0 6.4e-10 38.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP05245.1 - 0.026 13.3 0.5 0.037 12.8 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Pkinase PF00069.25 KFP05246.1 - 0.0012 18.3 0.0 0.0014 18.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 KFP05247.1 - 3.7e-65 219.9 0.1 4.4e-65 219.7 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP05247.1 - 7.6e-27 94.2 0.1 1.1e-26 93.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFP05247.1 - 5.4e-05 23.2 0.1 0.00011 22.2 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFP05247.1 - 0.00039 19.8 0.2 0.00059 19.2 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFP05247.1 - 0.0046 16.3 0.2 0.015 14.6 0.0 1.9 2 1 0 2 2 2 1 Kinase-like DUF3754 PF12576.8 KFP05247.1 - 0.02 14.8 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) Haspin_kinase PF12330.8 KFP05247.1 - 0.029 13.3 0.1 0.045 12.7 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KFP05247.1 - 0.076 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 zf-HC5HC2H_2 PF13832.6 KFP05248.1 - 1.2e-36 125.1 6.1 1.2e-36 125.1 6.1 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 KFP05248.1 - 5.2e-35 121.2 0.4 5.2e-35 121.2 0.4 3.1 3 0 0 3 3 3 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 KFP05248.1 - 2.3e-25 88.7 4.1 2.3e-25 88.7 4.1 3.4 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.25 KFP05248.1 - 2.1e-24 85.4 0.1 5.3e-24 84.1 0.1 1.7 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.17 KFP05248.1 - 2.6e-17 63.0 0.0 1.1e-16 61.0 0.0 2.2 1 0 0 1 1 1 1 PWWP domain PHD_2 PF13831.6 KFP05248.1 - 3.9e-12 45.5 6.8 3.9e-12 45.5 6.8 2.7 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 KFP05248.1 - 2.3e-06 27.4 28.6 0.0001 22.1 16.8 2.7 2 0 0 2 2 2 2 PHD-finger DNA_topoisoIV PF00521.20 KFP05248.1 - 0.022 13.7 4.3 0.041 12.8 4.3 1.4 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Elf-1_N PF12310.8 KFP05248.1 - 0.1 13.2 0.0 0.33 11.5 0.0 1.8 1 0 0 1 1 1 0 Transcription factor protein N terminal C1_1 PF00130.22 KFP05248.1 - 1.9 8.4 19.2 0.041 13.8 6.5 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RabGAP-TBC PF00566.18 KFP05249.1 - 5.1e-53 179.9 2.1 7.1e-53 179.4 2.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF4864 PF16156.5 KFP05249.1 - 0.095 13.4 0.0 0.23 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4864) MIF4G PF02854.19 KFP05249.1 - 0.095 12.3 0.0 1.7 8.2 0.0 2.4 1 1 1 2 2 2 0 MIF4G domain Pkinase PF00069.25 KFP05250.1 - 4.2e-47 160.7 0.0 5.7e-47 160.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP05250.1 - 1.8e-12 47.1 0.0 3.5e-12 46.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFP05250.1 - 1.9e-06 27.4 0.0 2.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFP05250.1 - 2e-06 27.3 0.0 2.4e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP05250.1 - 0.03 13.1 0.0 0.035 12.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KFP05250.1 - 0.033 14.1 0.2 0.054 13.4 0.2 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFP05250.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 KFP05250.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KFP05250.1 - 0.18 11.3 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Mito_carr PF00153.27 KFP05251.1 - 8e-14 51.3 0.2 8.3e-09 35.3 0.0 2.7 3 0 0 3 3 3 2 Mitochondrial carrier protein CAP PF00188.26 KFP05252.1 - 6.7e-21 75.4 0.2 1.3e-20 74.5 0.2 1.5 1 1 0 1 1 1 1 Cysteine-rich secretory protein family FGAR-AT_linker PF18072.1 KFP05252.1 - 0.067 13.7 0.1 0.37 11.4 0.1 2.2 2 1 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain CDI PF02234.19 KFP05254.1 - 3.2e-20 72.1 4.4 3.5e-20 71.9 4.4 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor RRM_1 PF00076.22 KFP05255.1 - 3e-18 65.4 0.0 4.4e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP05255.1 - 0.0016 18.0 0.0 0.0022 17.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP05255.1 - 0.093 12.6 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Occluded RNA-recognition motif Pkinase PF00069.25 KFP05256.1 - 1.5e-58 198.2 0.1 1.5e-58 198.2 0.1 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP05256.1 - 5.8e-29 101.1 2.3 1.3e-20 73.8 0.2 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KFP05256.1 - 2e-07 31.6 1.2 5.2e-07 30.3 0.8 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KFP05256.1 - 1.6e-05 24.0 0.6 3.6e-05 22.9 0.2 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFP05256.1 - 5.3e-05 22.7 0.4 0.0015 17.9 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFP05256.1 - 0.0006 19.8 0.1 0.036 14.0 0.2 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFP05256.1 - 0.0014 18.0 0.0 0.0029 17.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KFP05256.1 - 0.094 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 MEKHLA PF08670.11 KFP05256.1 - 0.18 11.7 1.3 1.5 8.7 0.8 2.2 2 0 0 2 2 2 0 MEKHLA domain BTB_3 PF16017.5 KFP05257.1 - 3.4e-49 165.3 0.0 5.4e-49 164.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 KFP05257.1 - 1.3e-05 25.5 0.0 2.7e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.31 KFP05258.1 - 3.9e-51 173.7 7.2 5.2e-51 173.2 7.2 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFP05258.1 - 2.3e-28 98.4 0.0 4e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFP05258.1 - 1.1e-13 50.9 5.8 1.1e-13 50.9 5.8 2.5 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.12 KFP05258.1 - 0.0013 17.5 0.8 0.0019 16.9 0.3 1.5 1 1 0 1 1 1 1 Polycystin cation channel Sigma_reg_N PF13800.6 KFP05258.1 - 0.18 12.1 0.8 26 5.2 0.1 3.5 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Ion_trans PF00520.31 KFP05259.1 - 1e-51 175.6 5.2 1.4e-51 175.1 5.2 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFP05259.1 - 2e-18 66.5 0.1 3.9e-18 65.6 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFP05259.1 - 1.1e-13 51.0 5.8 1.1e-13 51.0 5.8 2.5 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.12 KFP05259.1 - 0.0011 17.7 0.9 0.0027 16.4 0.9 1.6 1 0 0 1 1 1 1 Polycystin cation channel Sigma_reg_N PF13800.6 KFP05259.1 - 0.12 12.7 0.6 25 5.3 0.1 3.5 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Ion_trans PF00520.31 KFP05260.1 - 1.8e-51 174.7 9.0 2.5e-51 174.3 9.0 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFP05260.1 - 2e-28 98.6 0.0 3.5e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFP05260.1 - 1.6e-14 53.6 4.7 1.6e-14 53.6 4.7 2.5 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.12 KFP05260.1 - 0.013 14.2 0.9 0.013 14.2 0.9 1.6 2 0 0 2 2 2 0 Polycystin cation channel Sigma_reg_N PF13800.6 KFP05260.1 - 0.098 13.0 0.7 10 6.5 0.0 3.4 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Ion_trans PF00520.31 KFP05261.1 - 4.2e-49 167.0 12.9 5.4e-49 166.6 12.9 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFP05261.1 - 9.8e-24 83.5 0.1 2.4e-23 82.3 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFP05261.1 - 2.1e-13 50.0 5.8 2.1e-13 50.0 5.8 2.9 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.12 KFP05261.1 - 0.001 17.9 0.2 0.001 17.9 0.2 2.4 1 1 2 3 3 3 1 Polycystin cation channel DUF423 PF04241.15 KFP05261.1 - 0.46 10.7 3.3 0.92 9.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF423) DUF202 PF02656.15 KFP05261.1 - 1.1 9.8 5.5 1.1e+02 3.3 4.8 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Sigma_reg_N PF13800.6 KFP05261.1 - 3.9 7.8 7.4 16 5.8 0.1 3.6 4 0 0 4 4 4 0 Sigma factor regulator N-terminal Ig_3 PF13927.6 KFP05262.1 - 2.2e-75 249.3 0.5 4.2e-14 52.9 0.0 7.1 7 0 0 7 7 7 6 Immunoglobulin domain I-set PF07679.16 KFP05262.1 - 1.8e-72 239.5 0.0 2.5e-13 49.9 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP05262.1 - 1.9e-50 169.1 0.0 9.6e-10 38.7 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.25 KFP05262.1 - 4e-45 151.9 0.0 3.2e-09 36.8 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin domain fn3 PF00041.21 KFP05262.1 - 2.5e-42 143.1 16.9 5.5e-12 45.9 0.1 5.6 5 0 0 5 5 5 5 Fibronectin type III domain Bravo_FIGEY PF13882.6 KFP05262.1 - 1.1e-26 94.0 5.9 3.1e-26 92.6 5.9 1.8 1 0 0 1 1 1 1 Bravo-like intracellular region V-set PF07686.17 KFP05262.1 - 2.2e-15 56.8 6.6 0.0012 19.0 0.0 9.7 8 4 2 10 10 10 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP05262.1 - 8.4e-10 38.6 0.4 0.15 12.2 0.0 6.4 6 2 1 7 7 7 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFP05262.1 - 9.4e-10 37.9 0.0 0.15 11.7 0.0 5.8 5 0 0 5 5 5 2 Immunoglobulin domain Ig_5 PF16681.5 KFP05262.1 - 1.9e-08 34.6 0.0 0.027 14.9 0.0 5.1 5 0 0 5 5 5 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFP05262.1 - 2.4e-07 30.9 2.1 0.87 9.9 0.0 6.2 6 1 0 6 6 6 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFP05262.1 - 0.0013 18.7 0.0 16 5.7 0.0 4.4 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain BiPBP_C PF06832.12 KFP05262.1 - 0.0018 18.3 0.0 0.35 10.9 0.0 3.8 5 0 0 5 5 4 1 Penicillin-Binding Protein C-terminus Family V-set_CD47 PF08204.11 KFP05262.1 - 0.0048 16.9 0.3 12 5.9 0.0 3.9 4 0 0 4 4 3 0 CD47 immunoglobulin-like domain Herpes_gE PF02480.16 KFP05262.1 - 0.055 12.2 0.0 2.9 6.6 0.0 3.1 3 1 1 4 4 4 0 Alphaherpesvirus glycoprotein E Ig_3 PF13927.6 KFP05263.1 - 2.5e-74 245.9 1.0 3.2e-12 46.9 0.0 7.4 7 0 0 7 7 7 6 Immunoglobulin domain I-set PF07679.16 KFP05263.1 - 5.2e-68 225.2 0.0 8.1e-16 57.9 0.0 6.8 7 0 0 7 7 7 6 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP05263.1 - 2.7e-52 175.0 0.0 7.6e-11 42.2 0.0 6.5 5 1 1 6 6 6 5 Immunoglobulin domain ig PF00047.25 KFP05263.1 - 5.6e-51 170.7 1.2 6.1e-09 35.9 0.0 6.9 7 0 0 7 7 6 6 Immunoglobulin domain fn3 PF00041.21 KFP05263.1 - 6.9e-45 151.3 4.5 2e-16 60.1 0.0 4.5 4 0 0 4 4 4 4 Fibronectin type III domain V-set PF07686.17 KFP05263.1 - 9.3e-22 77.3 7.8 0.01 16.0 0.0 9.5 6 4 1 8 8 8 5 Immunoglobulin V-set domain Ig_6 PF18452.1 KFP05263.1 - 5.1e-13 48.4 0.0 0.0058 16.2 0.0 6.2 6 0 0 6 6 6 2 Immunoglobulin domain Ig_5 PF16681.5 KFP05263.1 - 2.6e-12 47.0 0.0 0.97 9.9 0.0 6.3 6 1 0 6 6 6 4 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFP05263.1 - 2.6e-10 40.4 0.1 0.12 12.6 0.0 5.4 6 0 0 6 6 5 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFP05263.1 - 5.5e-09 36.0 0.1 0.18 11.9 0.0 5.7 6 0 0 6 6 6 2 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 KFP05263.1 - 9.3e-09 35.2 0.1 0.7 10.0 0.0 6.3 6 0 0 6 6 6 2 C17orf99 Ig domain Pur_ac_phosph_N PF16656.5 KFP05263.1 - 2.9e-07 30.9 0.0 0.00083 19.9 0.1 3.4 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain C2-set_2 PF08205.12 KFP05263.1 - 8.1e-07 29.0 1.7 0.03 14.4 0.0 4.8 5 0 0 5 5 5 1 CD80-like C2-set immunoglobulin domain C2-set PF05790.15 KFP05263.1 - 0.00023 21.3 0.1 9.5 6.5 0.0 5.4 5 1 1 6 6 6 1 Immunoglobulin C2-set domain Interfer-bind PF09294.10 KFP05263.1 - 0.012 15.9 0.0 0.22 11.8 0.0 2.6 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III Izumo-Ig PF16706.5 KFP05264.1 - 0.00011 22.2 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 Izumo-like Immunoglobulin domain ig PF00047.25 KFP05264.1 - 0.0022 18.2 0.0 0.0057 16.8 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP05264.1 - 0.024 14.8 0.0 0.088 13.0 0.0 1.9 1 1 0 1 1 1 0 Immunoglobulin V-set domain Ig_6 PF18452.1 KFP05264.1 - 0.038 13.6 0.0 0.077 12.6 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.6 KFP05264.1 - 0.042 14.5 0.0 0.086 13.5 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Ig_2 PF13895.6 KFP05264.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain TSP_1 PF00090.19 KFP05264.1 - 1.3 9.3 6.3 0.87 9.9 2.7 2.2 2 0 0 2 2 2 0 Thrombospondin type 1 domain WD40 PF00400.32 KFP05265.1 - 7.5e-11 42.4 18.4 0.00021 22.0 1.7 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP05265.1 - 5.2e-10 39.5 0.3 0.011 16.0 0.0 3.9 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain BUD22 PF09073.10 KFP05265.1 - 1.7 7.9 12.0 2.5 7.3 12.0 1.2 1 0 0 1 1 1 0 BUD22 Pkinase PF00069.25 KFP05266.1 - 4.2e-37 128.0 0.0 1.1e-36 126.5 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP05266.1 - 9.2e-36 123.4 0.0 1.7e-35 122.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP05266.1 - 3.6e-05 22.7 0.0 6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFP05266.1 - 9.3e-05 21.9 0.0 0.0002 20.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFP05266.1 - 0.00038 19.5 0.0 0.00096 18.2 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFP05266.1 - 0.0018 17.7 0.6 0.0042 16.5 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP05266.1 - 0.3 11.0 0.0 0.3 11.0 0.0 3.0 4 0 0 4 4 4 0 Phosphotransferase enzyme family Tmemb_cc2 PF10267.9 KFP05267.1 - 1e-177 591.3 6.7 1.5e-177 590.8 6.7 1.2 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein LMBR1 PF04791.16 KFP05267.1 - 0.00096 18.2 5.1 0.0042 16.1 0.6 2.1 2 0 0 2 2 2 1 LMBR1-like membrane protein Exonuc_VII_L PF02601.15 KFP05267.1 - 0.0023 17.6 16.3 0.15 11.6 0.7 2.2 2 0 0 2 2 2 2 Exonuclease VII, large subunit TraG_N PF07916.11 KFP05267.1 - 0.0041 16.0 0.5 0.0088 14.9 0.5 1.5 1 0 0 1 1 1 1 TraG-like protein, N-terminal region Prominin PF05478.11 KFP05267.1 - 0.0054 14.8 18.0 0.0054 14.8 7.8 2.2 2 0 0 2 2 2 2 Prominin 7TMR-HDED PF07697.11 KFP05267.1 - 0.0071 16.5 13.0 0.19 11.8 0.4 2.4 2 0 0 2 2 2 2 7TM-HD extracellular Baculo_PEP_C PF04513.12 KFP05267.1 - 0.037 14.1 0.8 0.037 14.1 0.8 3.5 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1479 PF07350.12 KFP05267.1 - 0.051 12.3 4.2 0.12 11.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) Atg14 PF10186.9 KFP05267.1 - 0.062 12.4 20.5 0.055 12.5 3.6 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2313 PF10076.9 KFP05267.1 - 0.1 12.5 5.9 0.051 13.4 0.9 2.4 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2313) Lipoprotein_20 PF13942.6 KFP05267.1 - 0.41 10.6 17.9 0.7 9.8 2.1 2.5 2 1 0 2 2 2 0 YfhG lipoprotein UPF0565 PF10561.9 KFP05267.1 - 0.45 9.7 5.1 0.15 11.3 0.3 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 CorA PF01544.18 KFP05267.1 - 0.84 8.9 14.2 0.59 9.4 4.1 2.7 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein GET2 PF08690.10 KFP05267.1 - 1.1 8.8 9.0 0.069 12.8 0.3 2.4 2 1 0 2 2 2 0 GET complex subunit GET2 OmpH PF03938.14 KFP05267.1 - 1.8 8.9 37.1 7.9 6.8 18.1 3.4 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF1690 PF07956.11 KFP05267.1 - 1.8 9.0 22.9 7 7.1 8.5 2.6 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Erythro_esteras PF05139.14 KFP05267.1 - 3 7.6 10.7 0.44 10.3 0.3 2.2 2 0 0 2 2 2 0 Erythromycin esterase Phage_GPO PF05929.11 KFP05267.1 - 9.4 5.8 22.1 0.43 10.2 4.4 3.4 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase CortBP2 PF09727.9 KFP05267.1 - 9.9 6.0 28.2 0.29 11.0 13.9 2.5 2 0 0 2 2 2 0 Cortactin-binding protein-2 Kelch_1 PF01344.25 KFP05268.1 - 2.2e-48 161.6 0.5 7.5e-10 38.2 0.0 7.1 7 0 0 7 7 7 7 Kelch motif Kelch_6 PF13964.6 KFP05268.1 - 1.1e-36 123.9 0.5 5.7e-08 32.8 0.0 7.1 3 3 4 7 7 7 7 Kelch motif Kelch_4 PF13418.6 KFP05268.1 - 9.8e-22 76.7 0.1 2.3e-06 27.5 0.0 6.4 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP05268.1 - 1.5e-19 69.1 0.0 3.9e-05 23.4 0.0 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 KFP05268.1 - 8.9e-18 64.1 0.2 0.0011 19.2 0.0 6.2 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP05268.1 - 1.4e-09 37.8 1.3 0.0086 16.0 0.0 5.1 5 0 0 5 5 5 2 Kelch motif WYL_2 PF10902.8 KFP05268.1 - 0.18 12.2 0.3 51 4.3 0.0 3.3 4 0 0 4 4 4 0 WYL_2, Sm-like SH3 beta-barrel fold Ribosomal_L34e PF01199.18 KFP05269.1 - 6e-43 145.1 7.3 7.6e-43 144.8 7.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e OST3_OST6 PF04756.13 KFP05270.1 - 2.4e-06 27.1 0.4 2.8e-06 26.9 0.4 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Aminotran_3 PF00202.21 KFP05271.1 - 4.9e-84 282.3 0.0 6.1e-84 282.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Sec23_trunk PF04811.15 KFP05272.1 - 8e-79 264.6 0.1 1.9e-78 263.4 0.0 1.6 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KFP05272.1 - 6.7e-27 93.3 3.6 2.1e-26 91.7 3.6 2.0 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KFP05272.1 - 3.3e-21 75.8 0.0 9e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KFP05272.1 - 1.1e-14 54.2 5.3 2.2e-14 53.2 5.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KFP05272.1 - 1.9e-10 40.5 0.0 4.2e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Sen15 PF09631.10 KFP05272.1 - 0.061 13.6 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 Sen15 protein HpaB PF03241.13 KFP05272.1 - 0.13 11.3 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal MCU PF04678.13 KFP05273.1 - 4.8e-68 228.7 1.6 6.1e-68 228.4 1.6 1.1 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Nup96 PF12110.8 KFP05273.1 - 0.0066 15.6 0.3 0.021 14.0 0.1 1.6 1 1 1 2 2 2 1 Nuclear protein 96 Creatinase_N_2 PF16189.5 KFP05273.1 - 0.13 12.3 1.3 0.21 11.7 0.4 1.7 2 0 0 2 2 2 0 Creatinase/Prolidase N-terminal domain CHD5 PF04420.14 KFP05273.1 - 0.24 11.2 2.8 16 5.3 0.2 2.6 2 1 1 3 3 3 0 CHD5-like protein HARP PF07443.13 KFP05273.1 - 0.26 11.0 2.3 0.43 10.3 0.2 2.2 2 0 0 2 2 2 0 HepA-related protein (HARP) Ribosomal_L29 PF00831.23 KFP05273.1 - 0.65 10.0 5.8 0.72 9.9 0.9 2.4 2 0 0 2 2 2 0 Ribosomal L29 protein Peptidase_C14 PF00656.22 KFP05274.1 - 4.7e-56 190.5 0.0 5.6e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain PLA2G12 PF06951.11 KFP05275.1 - 1.3e-61 207.6 10.1 1.5e-61 207.5 10.1 1.0 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) Phospholip_A2_2 PF05826.12 KFP05275.1 - 0.51 10.6 14.8 0.88 9.8 2.6 2.5 1 1 1 2 2 2 0 Phospholipase A2 Trypsin PF00089.26 KFP05276.1 - 3.5e-34 118.6 0.0 3.5e-34 118.6 0.0 1.6 2 0 0 2 2 2 1 Trypsin Ldl_recept_a PF00057.18 KFP05276.1 - 6.6e-15 55.0 29.5 5.3e-09 36.1 13.2 4.2 4 0 0 4 4 4 2 Low-density lipoprotein receptor domain class A SRCR PF00530.18 KFP05276.1 - 7.2e-10 39.3 1.7 7.2e-10 39.3 1.7 3.1 2 1 1 3 3 3 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFP05276.1 - 7e-05 23.3 3.3 7.1e-05 23.3 0.8 2.2 1 1 1 2 2 2 1 Scavenger receptor cysteine-rich domain Trypsin_2 PF13365.6 KFP05276.1 - 0.029 15.3 0.0 0.053 14.4 0.0 1.4 1 0 0 1 1 1 0 Trypsin-like peptidase domain Gar1 PF04410.14 KFP05277.1 - 1.6e-34 118.9 0.0 2e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region 7tm_1 PF00001.21 KFP05278.1 - 3.8e-43 147.7 14.9 4.7e-43 147.4 14.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP05278.1 - 2.2e-11 43.6 12.2 2.7e-11 43.3 12.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx NOT2_3_5 PF04153.18 KFP05278.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family TMEM223 PF14640.6 KFP05278.1 - 0.27 11.4 4.8 0.32 11.2 1.8 2.4 2 0 0 2 2 2 0 Transmembrane protein 223 Ldl_recept_b PF00058.17 KFP05279.1 - 3.1e-42 142.8 3.3 2.9e-09 37.2 0.0 7.9 8 0 0 8 8 8 6 Low-density lipoprotein receptor repeat class B cEGF PF12662.7 KFP05279.1 - 1.2e-35 121.0 75.0 1.6e-05 24.7 4.2 11.3 11 0 0 11 11 11 9 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFP05279.1 - 1.5e-35 121.1 145.8 7.7e-08 32.5 5.6 11.4 11 0 0 11 11 11 8 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 KFP05279.1 - 1.1e-21 76.8 51.4 1.5e-07 31.4 10.1 11.3 11 0 0 11 11 11 5 Calcium-binding EGF domain EGF PF00008.27 KFP05279.1 - 8.2e-18 64.4 123.9 5.3e-05 23.4 4.3 11.2 11 0 0 11 11 11 8 EGF-like domain EGF_3 PF12947.7 KFP05279.1 - 1.2e-12 47.8 123.1 5.3e-06 26.5 12.0 10.8 10 0 0 10 10 10 7 EGF domain DUF5050 PF16472.5 KFP05279.1 - 2e-10 40.4 0.0 8e-06 25.3 0.0 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF5050) SGL PF08450.12 KFP05279.1 - 4.6e-07 29.7 0.2 0.31 10.6 0.0 4.5 2 1 2 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region hEGF PF12661.7 KFP05279.1 - 0.00099 19.7 97.9 0.035 14.7 6.6 10.6 9 0 0 9 9 9 5 Human growth factor-like EGF PEPCK_ATP PF01293.20 KFP05279.1 - 0.17 10.5 2.7 0.27 9.8 2.7 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase ELO PF01151.18 KFP05280.1 - 2.2e-67 227.2 24.8 2.6e-67 227.0 24.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Homeodomain PF00046.29 KFP05281.1 - 7.1e-23 80.2 9.4 1.2e-22 79.5 9.4 1.4 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 KFP05281.1 - 7.2e-09 35.2 1.2 1.6e-08 34.1 1.2 1.6 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 KFP05281.1 - 0.0031 17.4 0.6 0.0031 17.4 0.6 2.2 2 0 0 2 2 2 1 Homeobox KN domain DUF4605 PF15378.6 KFP05282.1 - 7.6e-26 89.7 6.4 7.6e-26 89.7 6.4 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4605) PHO4 PF01384.20 KFP05283.1 - 1.2e-139 465.1 7.6 1.5e-139 464.8 7.6 1.1 1 0 0 1 1 1 1 Phosphate transporter family Vpu PF00558.19 KFP05283.1 - 0.023 14.4 0.2 0.023 14.4 0.2 2.1 2 0 0 2 2 2 0 Vpu protein Syndecan PF01034.20 KFP05283.1 - 4.5 7.3 4.7 6 6.9 0.0 3.4 3 0 0 3 3 3 0 Syndecan domain Pkinase_Tyr PF07714.17 KFP05284.1 - 8.9e-09 35.0 0.1 1.4e-07 31.1 0.1 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KFP05284.1 - 1.7e-05 24.3 0.0 0.0006 19.3 0.1 2.2 2 0 0 2 2 2 1 Protein kinase domain PIP49_C PF12260.8 KFP05284.1 - 0.00031 20.4 0.1 0.00048 19.8 0.1 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 PIP49_N PF14875.6 KFP05284.1 - 0.044 13.6 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 N-term cysteine-rich ER, FAM69 TPR_19 PF14559.6 KFP05285.1 - 0.074 13.6 0.2 0.44 11.1 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat CHGN PF05679.16 KFP05286.1 - 9.4e-81 272.2 0.8 1.2e-80 271.9 0.8 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 KFP05286.1 - 2.7e-09 36.6 1.3 6.3e-09 35.4 1.3 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KFP05286.1 - 1.9e-05 24.3 0.4 6.9e-05 22.4 0.4 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KFP05286.1 - 0.0025 17.7 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Jnk-SapK_ap_N PF09744.9 KFP05286.1 - 0.03 14.6 0.5 0.058 13.6 0.5 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4094 PF13334.6 KFP05286.1 - 0.1 13.0 0.0 0.3 11.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) SH2 PF00017.24 KFP05287.1 - 8.9e-14 51.4 0.0 2e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 SH2 domain Sulfotransfer_1 PF00685.27 KFP05288.1 - 4.3e-86 288.7 0.0 5e-86 288.5 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP05288.1 - 1.7e-05 25.3 0.2 0.0071 16.8 0.1 2.3 2 0 0 2 2 2 2 Sulfotransferase family UDPGT PF00201.18 KFP05289.1 - 1.9e-223 742.8 0.0 2.1e-223 742.7 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KFP05289.1 - 1.6e-06 28.2 0.0 2.8e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Pro_3_hydrox_C PF05373.11 KFP05289.1 - 0.029 14.5 0.0 0.064 13.4 0.0 1.5 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal Glyco_trans_1_3 PF13528.6 KFP05289.1 - 0.077 12.2 0.0 7.8 5.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 1 YTH PF04146.15 KFP05290.1 - 2.3e-41 141.5 0.1 2.3e-41 141.5 0.1 3.7 2 2 0 2 2 2 1 YT521-B-like domain Pkinase_Tyr PF07714.17 KFP05291.1 - 7.1e-100 333.6 0.0 8.3e-100 333.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP05291.1 - 1.7e-49 168.6 0.0 2e-49 168.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.6 KFP05291.1 - 1.3e-15 58.0 0.3 2.4e-15 57.2 0.3 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Haspin_kinase PF12330.8 KFP05291.1 - 0.0033 16.4 0.0 0.0051 15.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFP05291.1 - 0.0097 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFP05291.1 - 0.032 13.0 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase ADH_zinc_N PF00107.26 KFP05292.1 - 2.1e-27 95.7 0.1 4e-27 94.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFP05292.1 - 6.5e-26 90.4 0.6 1.4e-25 89.3 0.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain IGFBP PF00219.18 KFP05292.1 - 0.012 16.2 0.2 0.034 14.8 0.2 1.7 1 0 0 1 1 1 0 Insulin-like growth factor binding protein 2-Hacid_dh_C PF02826.19 KFP05292.1 - 0.016 14.5 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KFP05292.1 - 0.049 13.2 1.1 0.13 11.9 0.9 1.8 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N_2 PF13602.6 KFP05292.1 - 0.094 13.8 0.0 0.18 12.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N PF08240.12 KFP05293.1 - 1.3e-25 89.4 1.1 3.4e-25 88.0 1.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFP05293.1 - 1.8e-23 82.9 0.4 3.6e-23 82.0 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFP05293.1 - 0.0014 19.6 0.0 0.0026 18.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KFP05293.1 - 0.091 12.1 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peptidase_M24 PF00557.24 KFP05294.1 - 3.1e-54 183.9 0.3 3.8e-54 183.6 0.3 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KFP05294.1 - 0.0043 17.3 1.1 0.0043 17.3 1.1 1.9 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding Pyr_redox_dim PF02852.22 KFP05294.1 - 0.1 12.8 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain IF4E PF01652.18 KFP05295.1 - 2.7e-56 189.8 0.1 3.2e-56 189.5 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Tetraspanin PF00335.20 KFP05296.1 - 3e-62 210.3 9.7 3.5e-62 210.1 9.7 1.0 1 0 0 1 1 1 1 Tetraspanin family Arm PF00514.23 KFP05297.1 - 2.5e-32 109.9 18.0 1.6e-08 34.3 0.2 8.1 8 0 0 8 8 8 5 Armadillo/beta-catenin-like repeat WAPL PF07814.13 KFP05297.1 - 0.0005 19.0 11.2 0.019 13.8 0.0 3.9 3 1 2 5 5 5 2 Wings apart-like protein regulation of heterochromatin HEAT_2 PF13646.6 KFP05297.1 - 0.002 18.5 7.9 0.84 10.1 0.0 4.7 3 2 0 3 3 3 1 HEAT repeats RTTN_N PF14726.6 KFP05297.1 - 0.0075 17.0 7.4 4.7 8.1 0.0 4.4 2 1 2 4 4 4 2 Rotatin, an armadillo repeat protein, centriole functioning HEAT_EZ PF13513.6 KFP05297.1 - 0.0087 16.5 10.3 1.3 9.6 0.1 5.1 5 0 0 5 5 5 2 HEAT-like repeat Nitr_red_bet_C PF14711.6 KFP05297.1 - 0.079 12.7 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal HEAT PF02985.22 KFP05297.1 - 0.22 11.9 1.9 1.3e+02 3.2 0.0 4.8 3 0 0 3 3 3 0 HEAT repeat Yae1_N PF09811.9 KFP05298.1 - 2.1e-12 46.5 40.7 1.8e+04 -6.1 40.7 4.2 1 1 0 1 1 1 0 Essential protein Yae1, N terminal UPA PF17217.3 KFP05299.1 - 1.2e-71 239.1 0.4 2.1e-71 238.3 0.4 1.4 1 0 0 1 1 1 1 UPA domain ZU5 PF00791.20 KFP05299.1 - 1.2e-34 118.5 0.0 3.1e-34 117.2 0.0 1.7 1 0 0 1 1 1 1 ZU5 domain Death PF00531.22 KFP05299.1 - 1.5e-13 50.7 0.2 4.1e-13 49.3 0.1 1.9 2 0 0 2 2 2 1 Death domain Ig_3 PF13927.6 KFP05299.1 - 3.5e-13 50.0 0.2 3.7e-09 37.0 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFP05299.1 - 3.1e-12 46.4 1.8 6.2e-11 42.2 0.1 3.1 3 0 0 3 3 3 1 Immunoglobulin I-set domain TSP_1 PF00090.19 KFP05299.1 - 3.1e-10 40.1 29.7 4e-08 33.3 8.8 2.7 2 0 0 2 2 2 2 Thrombospondin type 1 domain Ig_2 PF13895.6 KFP05299.1 - 6e-08 32.9 0.1 7.3e-06 26.2 0.0 3.5 3 0 0 3 3 3 1 Immunoglobulin domain ig PF00047.25 KFP05299.1 - 1.6e-06 28.2 0.0 3.6e-05 23.9 0.0 2.9 3 0 0 3 3 3 1 Immunoglobulin domain V-set PF07686.17 KFP05299.1 - 0.012 15.8 0.4 1.8 8.8 0.1 3.2 2 1 0 2 2 2 0 Immunoglobulin V-set domain AtuA PF07287.11 KFP05299.1 - 0.032 13.0 0.0 0.053 12.2 0.0 1.2 1 0 0 1 1 1 0 Acyclic terpene utilisation family protein AtuA SKG6 PF08693.10 KFP05299.1 - 0.12 11.8 1.9 0.29 10.6 1.9 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 KFP05299.1 - 0.18 11.6 2.5 0.39 10.5 2.5 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Pkinase_Tyr PF07714.17 KFP05300.1 - 9.9e-38 129.9 0.0 1.3e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP05300.1 - 4e-36 124.7 0.0 6.4e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.12 KFP05300.1 - 4.3e-16 58.1 0.5 9.2e-16 57.0 0.5 1.6 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.23 KFP05300.1 - 5.7e-10 40.1 2.4 6.2e-10 40.0 0.8 1.8 2 0 0 2 2 2 1 Activin types I and II receptor domain FTA2 PF13095.6 KFP05300.1 - 0.008 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Adeno_E3_CR2 PF02439.15 KFP05300.1 - 0.019 14.7 0.6 0.035 13.9 0.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Haspin_kinase PF12330.8 KFP05300.1 - 0.081 11.9 0.1 0.14 11.1 0.1 1.4 1 1 0 1 1 1 0 Haspin like kinase domain UPAR_LY6_2 PF16975.5 KFP05300.1 - 0.11 12.7 0.4 0.26 11.5 0.4 1.6 1 0 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 Protocadherin PF08374.11 KFP05300.1 - 0.19 11.7 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Protocadherin APH PF01636.23 KFP05300.1 - 0.2 11.5 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family 7tm_1 PF00001.21 KFP05301.1 - 3.6e-53 180.6 19.7 4.5e-53 180.3 19.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP05301.1 - 7.2e-17 61.6 16.4 9.2e-17 61.3 16.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP05301.1 - 1.6e-12 47.6 19.9 2.8e-12 46.8 19.9 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFP05301.1 - 1.7e-09 37.5 7.0 3e-09 36.6 7.0 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFP05301.1 - 0.00019 21.3 13.8 0.0025 17.6 13.8 2.5 1 1 0 1 1 1 1 Olfactory receptor Git3 PF11710.8 KFP05301.1 - 0.00049 19.9 11.8 0.00049 19.9 11.8 1.5 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 SNARE PF05739.19 KFP05301.1 - 1.1 9.3 3.8 19 5.3 0.1 2.6 2 0 0 2 2 2 0 SNARE domain GST_C_3 PF14497.6 KFP05303.1 - 3.7e-17 62.3 0.0 6.6e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFP05303.1 - 5.9e-12 45.8 0.1 1.3e-11 44.6 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFP05303.1 - 1.3e-05 25.4 0.1 1.9e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFP05303.1 - 0.00031 21.1 0.0 0.0007 20.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KFP05303.1 - 0.0016 19.1 0.0 0.0028 18.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 KFP05303.1 - 0.0028 17.7 1.3 0.0078 16.2 1.3 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFP05303.1 - 0.0051 17.1 0.0 0.01 16.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KFP05303.1 - 0.038 13.8 0.1 0.09 12.6 0.1 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SNF2_N PF00176.23 KFP05304.1 - 5.1e-59 199.8 2.1 8.5e-59 199.0 2.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFP05304.1 - 5.6e-18 65.3 0.0 2.1e-17 63.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP05304.1 - 2.1e-09 37.6 0.4 1.4e-08 34.9 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CUE PF02845.16 KFP05304.1 - 9.9e-07 28.4 0.6 0.035 13.8 0.0 2.7 2 0 0 2 2 2 2 CUE domain ERCC3_RAD25_C PF16203.5 KFP05304.1 - 7.5e-06 25.3 1.6 1.1e-05 24.8 0.1 2.0 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase HHH_3 PF12836.7 KFP05304.1 - 0.01 16.1 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Pre-PUA PF17832.1 KFP05304.1 - 0.23 12.2 4.6 36 5.1 0.0 4.2 4 0 0 4 4 4 0 Pre-PUA-like domain Mito_carr PF00153.27 KFP05305.1 - 6.5e-53 176.6 5.1 2.3e-21 75.5 0.4 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFP05305.1 - 0.037 13.2 1.8 0.43 9.7 0.0 2.6 2 1 1 3 3 3 0 Gammaproteobacterial serine protease LRR_8 PF13855.6 KFP05306.1 - 4e-82 269.9 68.6 8.5e-16 57.5 4.9 7.6 2 1 7 9 9 9 9 Leucine rich repeat I-set PF07679.16 KFP05306.1 - 4.1e-54 180.6 0.0 1.5e-21 76.2 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP05306.1 - 1.7e-48 163.1 0.0 8.7e-17 61.5 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain LRR_4 PF12799.7 KFP05306.1 - 1e-38 130.7 47.3 1.9e-05 24.9 1.2 9.1 5 2 3 9 9 9 9 Leucine Rich repeats (2 copies) Ig_2 PF13895.6 KFP05306.1 - 1.7e-34 118.0 0.0 2.9e-11 43.5 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFP05306.1 - 2.2e-30 104.6 0.4 6.2e-11 42.3 0.1 3.6 3 0 0 3 3 3 3 Immunoglobulin domain LRR_5 PF13306.6 KFP05306.1 - 2.1e-27 95.6 0.0 2.8e-09 37.0 0.0 4.0 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP05306.1 - 1.6e-17 63.5 8.5 0.00015 21.3 0.0 5.4 1 1 4 5 5 5 5 Leucine-rich repeat V-set PF07686.17 KFP05306.1 - 3.2e-17 62.7 3.5 0.0001 22.4 0.0 5.7 3 3 0 3 3 3 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP05306.1 - 9.3e-11 41.6 0.0 0.00099 19.1 0.0 3.7 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain LRR_1 PF00560.33 KFP05306.1 - 6.3e-09 35.2 37.1 11 7.0 0.1 14.1 15 0 0 15 15 14 0 Leucine Rich Repeat Ig_5 PF16681.5 KFP05306.1 - 2e-08 34.5 0.0 0.078 13.4 0.0 4.0 3 1 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFP05306.1 - 6.9e-06 25.5 0.0 1.6 8.4 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFP05306.1 - 5.4e-05 23.2 2.6 0.64 10.1 0.0 4.0 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain LRRCT PF01463.24 KFP05306.1 - 0.00032 21.0 0.0 0.0013 19.1 0.0 2.1 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain Ig_4 PF16680.5 KFP05306.1 - 0.0018 18.5 0.1 0.2 12.0 0.0 3.6 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 KFP05306.1 - 0.0091 16.3 0.1 0.3 11.5 0.0 3.0 3 0 0 3 3 3 1 Immunoglobulin C1-set domain Receptor_2B4 PF11465.8 KFP05306.1 - 0.024 14.8 0.0 0.71 10.1 0.0 2.9 3 0 0 3 3 3 0 Natural killer cell receptor 2B4 C2-set PF05790.15 KFP05306.1 - 0.027 14.6 0.1 14 6.0 0.0 3.3 3 0 0 3 3 3 0 Immunoglobulin C2-set domain DUF2201 PF09967.9 KFP05306.1 - 0.043 14.0 0.0 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 VWA-like domain (DUF2201) BACK PF07707.15 KFP05307.1 - 8.1e-32 109.4 1.3 7.5e-31 106.3 0.4 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_1 PF01344.25 KFP05307.1 - 7.8e-29 99.0 12.2 8e-11 41.3 0.6 5.5 5 0 0 5 5 5 4 Kelch motif BTB PF00651.31 KFP05307.1 - 2.5e-28 98.5 0.2 5.2e-28 97.5 0.2 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.6 KFP05307.1 - 1.8e-21 75.6 6.6 6.3e-05 23.1 0.0 5.9 4 2 1 5 5 5 5 Kelch motif Kelch_2 PF07646.15 KFP05307.1 - 3.9e-12 45.6 6.7 4.7e-06 26.4 0.2 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 KFP05307.1 - 1.4e-10 41.0 1.0 0.0094 15.9 0.0 4.4 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP05307.1 - 3e-09 37.0 2.0 0.013 15.8 0.0 4.6 5 0 0 5 5 5 2 Galactose oxidase, central domain DUF3342 PF11822.8 KFP05307.1 - 0.0092 16.2 0.8 0.067 13.4 0.0 2.7 3 1 0 3 3 3 1 Domain of unknown function (DUF3342) DUF4262 PF14081.6 KFP05307.1 - 0.078 13.2 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4262) Kelch_5 PF13854.6 KFP05307.1 - 0.099 12.7 5.0 40 4.4 0.0 4.1 4 0 0 4 4 4 0 Kelch motif PSII_BNR PF14870.6 KFP05307.1 - 0.1 11.8 0.0 0.25 10.6 0.0 1.6 2 0 0 2 2 2 0 Photosynthesis system II assembly factor YCF48 MFS_1 PF07690.16 KFP05308.1 - 1.6e-44 152.3 23.0 2.7e-38 131.8 25.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFP05308.1 - 3.8e-08 32.6 2.9 0.0056 15.6 0.0 3.8 1 1 1 3 3 3 3 MFS_1 like family ATP-grasp_2 PF08442.10 KFP05309.1 - 6.5e-77 257.7 0.8 1.1e-76 256.9 0.8 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 KFP05309.1 - 6e-27 94.4 0.2 1.3e-26 93.3 0.2 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KFP05309.1 - 2e-09 37.2 0.3 3.6e-09 36.4 0.1 1.4 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 KFP05309.1 - 0.0011 18.7 0.1 0.002 17.9 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain SepF PF04472.12 KFP05309.1 - 0.039 14.2 0.1 1.5 9.1 0.0 2.5 2 0 0 2 2 2 0 Cell division protein SepF TAFA PF12020.8 KFP05310.1 - 5.4e-45 151.8 12.6 6e-45 151.6 12.6 1.0 1 0 0 1 1 1 1 TAFA family EGF PF00008.27 KFP05310.1 - 6.1 7.2 14.3 0.69 10.3 0.7 3.4 2 1 0 2 2 2 0 EGF-like domain TAFA PF12020.8 KFP05311.1 - 1.6e-22 79.8 1.9 1.6e-22 79.8 1.9 1.5 2 0 0 2 2 2 1 TAFA family rhaM PF05336.13 KFP05311.1 - 0.13 12.3 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 L-rhamnose mutarotase DUF563 PF04577.14 KFP05312.1 - 4.7e-28 98.7 0.4 7.3e-28 98.1 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) TMF_TATA_bd PF12325.8 KFP05313.1 - 1.2e-32 112.5 11.2 1.2e-32 112.5 11.2 7.8 2 1 4 7 7 7 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KFP05313.1 - 5.5e-19 67.9 25.4 5.5e-19 67.9 25.4 10.5 6 3 5 12 12 12 5 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 KFP05313.1 - 0.0034 18.0 3.6 0.0034 18.0 3.6 10.4 4 3 6 10 10 10 2 SlyX NPH-II PF12011.8 KFP05313.1 - 0.12 12.3 1.9 0.54 10.1 1.9 2.2 1 0 0 1 1 1 0 RNA helicase NPH-II ThiF PF00899.21 KFP05314.1 - 2.3e-49 168.0 0.0 1.1e-48 165.7 0.0 1.8 1 1 0 1 1 1 1 ThiF family E2_bind PF08825.10 KFP05314.1 - 4.9e-25 87.5 0.4 9.9e-25 86.5 0.4 1.5 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 KFP05314.1 - 0.00092 19.3 0.1 0.0022 18.1 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UAE_UbL PF14732.6 KFP05314.1 - 0.0021 18.6 0.0 0.0042 17.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Pyr_redox PF00070.27 KFP05314.1 - 0.089 13.4 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PRA1 PF03208.19 KFP05315.1 - 6.2e-15 55.1 3.5 7.2e-15 54.9 3.5 1.0 1 0 0 1 1 1 1 PRA1 family protein Halogen_Hydrol PF10112.9 KFP05315.1 - 0.047 13.7 0.3 0.086 12.9 0.1 1.5 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein LapA_dom PF06305.11 KFP05315.1 - 0.059 13.2 3.0 1.6 8.6 0.0 2.5 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain PsbX PF06596.11 KFP05315.1 - 0.061 13.3 0.4 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) RBD-FIP PF09457.10 KFP05315.1 - 0.12 12.3 0.2 0.24 11.4 0.2 1.5 1 0 0 1 1 1 0 FIP domain DUF3487 PF11990.8 KFP05315.1 - 0.71 9.8 5.0 0.58 10.1 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3487) DUF3413 PF11893.8 KFP05315.1 - 8.9 5.4 9.7 37 3.4 0.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3413) DUF3338 PF11819.8 KFP05316.1 - 4.7e-54 182.0 8.0 4.7e-54 182.0 8.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3338) FERM_C PF09380.10 KFP05316.1 - 5.9e-23 81.1 0.5 1.9e-22 79.5 0.5 1.9 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 KFP05316.1 - 4.1e-18 65.9 2.4 2.6e-17 63.3 0.1 2.7 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.10 KFP05316.1 - 1.5e-11 44.0 0.5 4.3e-11 42.6 0.5 1.8 1 0 0 1 1 1 1 FERM N-terminal domain T2SSG PF08334.11 KFP05316.1 - 0.86 9.7 3.4 0.26 11.4 0.1 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein G zf-C4pol PF14260.6 KFP05316.1 - 4.4 7.8 4.7 1.3 9.5 0.5 2.2 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Med30 PF11315.8 KFP05316.1 - 9.7 6.4 9.0 12 6.1 3.8 2.4 2 0 0 2 2 2 0 Mediator complex subunit 30 DHQ_synthase PF01761.20 KFP05317.1 - 4e-57 193.3 0.0 5.1e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 KFP05317.1 - 1.4e-15 57.7 0.0 7.6e-15 55.3 0.0 1.9 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 KFP05317.1 - 7e-05 21.8 0.0 0.00012 21.0 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase SwrA PF17423.2 KFP05317.1 - 0.026 14.5 0.1 0.047 13.7 0.1 1.3 1 0 0 1 1 1 0 Swarming motility protein MDFI PF15316.6 KFP05318.1 - 3.1e-50 170.6 15.6 3.6e-50 170.4 15.6 1.0 1 0 0 1 1 1 1 MyoD family inhibitor FOXP-CC PF16159.5 KFP05319.1 - 2.6e-34 117.7 5.3 2.6e-34 117.7 5.3 4.7 5 1 1 6 6 6 1 FOXP coiled-coil domain Forkhead PF00250.18 KFP05319.1 - 4e-28 97.5 0.1 8.9e-28 96.4 0.1 1.6 1 0 0 1 1 1 1 Forkhead domain Zap1_zf2 PF18217.1 KFP05319.1 - 0.098 12.7 0.6 0.19 11.8 0.6 1.5 1 0 0 1 1 1 0 Zap1 zinc finger 2 Auxin_repressed PF05564.12 KFP05319.1 - 1.4 9.6 6.0 2 9.2 2.5 2.7 2 0 0 2 2 2 0 Dormancy/auxin associated protein Yae1_N PF09811.9 KFP05320.1 - 1.9e-21 75.5 79.6 1.8e+04 -37.9 79.6 6.2 1 1 0 1 1 1 0 Essential protein Yae1, N terminal IF4E PF01652.18 KFP05321.1 - 1.3e-36 125.8 0.0 1.6e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E 7tm_1 PF00001.21 KFP05322.1 - 7e-31 107.5 10.5 8.4e-31 107.2 10.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) UPF0114 PF03350.16 KFP05322.1 - 1.8 8.8 6.9 0.88 9.8 3.7 2.0 1 1 0 2 2 2 0 Uncharacterized protein family, UPF0114 Prokineticin PF06607.11 KFP05323.1 - 1.1e-39 134.6 9.4 1.2e-39 134.5 9.4 1.0 1 0 0 1 1 1 1 Prokineticin MIT_LIKE_ACTX PF17556.2 KFP05323.1 - 0.002 18.7 7.4 0.0027 18.3 7.4 1.3 1 0 0 1 1 1 1 MIT-like atracotoxin family YAF2_RYBP PF17219.3 KFP05324.1 - 1.4e-20 72.5 1.2 3.2e-20 71.4 1.2 1.6 1 0 0 1 1 1 1 Yaf2/RYBP C-terminal binding motif zf-RanBP PF00641.18 KFP05324.1 - 1.8e-08 33.5 2.4 3.6e-08 32.6 2.4 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others C1_2 PF03107.16 KFP05324.1 - 0.11 12.9 1.0 0.21 12.0 1.0 1.4 1 0 0 1 1 1 0 C1 domain DUF4808 PF16066.5 KFP05324.1 - 9.1 6.9 7.0 2.3 8.8 0.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4808) SHQ1 PF04925.15 KFP05325.1 - 2.1e-68 229.3 1.5 3.3e-68 228.7 1.5 1.3 1 0 0 1 1 1 1 SHQ1 protein Glyco_transf_8 PF01501.20 KFP05326.1 - 4e-12 46.2 0.0 7.1e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KFP05326.1 - 0.0023 17.4 0.5 0.0029 17.0 0.5 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 PPP4R2 PF09184.11 KFP05327.1 - 1.2e-77 261.4 11.7 1.2e-77 261.4 11.7 2.5 1 1 1 2 2 2 1 PPP4R2 CDC27 PF09507.10 KFP05327.1 - 8.6 5.6 41.4 11 5.2 41.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PDZ PF00595.24 KFP05328.1 - 6.4e-20 71.3 0.7 3e-14 53.1 0.1 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFP05328.1 - 1.4e-15 56.8 0.5 4e-12 45.8 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFP05328.1 - 7.5e-07 29.4 0.2 8.4e-06 26.0 0.1 2.4 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 KFP05328.1 - 0.013 15.5 0.0 0.036 14.0 0.0 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain zf-C3HC4_2 PF13923.6 KFP05329.1 - 4.5e-10 39.2 7.7 1.1e-09 38.0 7.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP05329.1 - 8.1e-08 32.0 6.2 2.1e-07 30.7 6.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PDZ PF00595.24 KFP05329.1 - 8.8e-08 32.4 0.3 1.5e-07 31.7 0.3 1.3 1 0 0 1 1 1 1 PDZ domain zf-RING_UBOX PF13445.6 KFP05329.1 - 2.7e-07 30.5 6.4 8e-07 29.0 6.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFP05329.1 - 1.4e-06 28.5 7.6 4.3e-06 26.9 7.6 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFP05329.1 - 1.7e-06 27.7 5.3 3.8e-06 26.7 5.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP05329.1 - 4.1e-06 26.6 7.2 9.6e-06 25.4 7.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFP05329.1 - 6e-06 26.1 6.3 1.5e-05 24.8 6.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFP05329.1 - 1.6e-05 24.9 7.5 3.4e-05 23.9 7.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KFP05329.1 - 0.0018 18.5 5.4 0.007 16.6 5.4 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain U-box PF04564.15 KFP05329.1 - 0.0059 16.7 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 U-box domain Sina PF03145.16 KFP05329.1 - 0.011 15.8 0.1 0.019 15.0 0.1 1.3 1 0 0 1 1 1 0 Seven in absentia protein family PDZ_2 PF13180.6 KFP05329.1 - 0.016 15.6 0.0 0.026 14.9 0.0 1.4 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 KFP05329.1 - 0.065 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 PDZ domain zf-RING_6 PF14835.6 KFP05329.1 - 0.068 13.1 3.3 0.19 11.6 2.8 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein CP12 PF02672.15 KFP05329.1 - 0.19 12.5 0.1 0.51 11.1 0.1 1.6 1 0 0 1 1 1 0 CP12 domain zf-RING_10 PF16685.5 KFP05329.1 - 0.25 11.5 7.0 0.58 10.3 7.0 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 Syntaxin_2 PF14523.6 KFP05330.1 - 8.2e-24 83.9 8.4 8.2e-24 83.9 8.4 2.2 2 0 0 2 2 2 1 Syntaxin-like protein Syntaxin PF00804.25 KFP05330.1 - 8.5e-09 35.4 11.0 3.7e-07 30.0 11.4 2.3 1 1 0 1 1 1 1 Syntaxin DUF1664 PF07889.12 KFP05330.1 - 0.027 14.5 10.6 2 8.4 1.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Cauli_AT PF03233.13 KFP05330.1 - 0.16 11.9 5.6 0.31 11.0 0.2 2.3 1 1 0 2 2 2 0 Aphid transmission protein DUF2849 PF11011.8 KFP05330.1 - 0.26 12.0 1.2 0.59 10.8 0.2 2.0 2 1 1 3 3 2 0 Protein of unknown function (DUF2849) MCPsignal PF00015.21 KFP05330.1 - 0.29 10.9 10.6 1.3 8.8 1.2 2.5 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FUSC PF04632.12 KFP05330.1 - 0.37 9.3 1.8 1.1 7.7 0.3 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein family 4HB_MCP_1 PF12729.7 KFP05330.1 - 0.47 10.0 7.3 0.085 12.4 1.5 2.3 2 1 0 2 2 2 0 Four helix bundle sensory module for signal transduction TMF_TATA_bd PF12325.8 KFP05330.1 - 0.66 10.2 10.3 5.4 7.3 0.7 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Noelin-1 PF12308.8 KFP05330.1 - 0.8 9.7 5.6 0.31 11.0 0.3 2.5 2 1 0 2 2 2 0 Neurogenesis glycoprotein MerR-DNA-bind PF09278.11 KFP05330.1 - 0.82 10.2 5.3 0.84 10.2 1.0 2.6 2 1 1 3 3 3 0 MerR, DNA binding Syntaxin-6_N PF09177.11 KFP05330.1 - 1.2 9.7 7.3 1.8 9.2 2.6 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal TMPIT PF07851.13 KFP05330.1 - 1.8 7.7 6.7 2.8 7.1 2.2 2.1 2 0 0 2 2 2 0 TMPIT-like protein NYD-SP28 PF14772.6 KFP05330.1 - 1.9 8.6 9.3 0.27 11.3 0.5 3.3 2 1 2 4 4 4 0 Sperm tail COMMD1_N PF17221.3 KFP05330.1 - 2.1 8.7 5.9 3.2 8.1 0.3 2.5 2 1 0 2 2 2 0 COMMD1 N-terminal domain DUF4446 PF14584.6 KFP05330.1 - 2.1 8.3 6.3 1.4 8.9 0.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) DASH_Dad1 PF08649.10 KFP05330.1 - 2.9 8.1 7.8 5.3 7.3 0.4 2.8 3 0 0 3 3 2 0 DASH complex subunit Dad1 Fib_alpha PF08702.10 KFP05330.1 - 4.8 7.4 13.3 1.3 9.2 5.5 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 KFP05330.1 - 5.3 7.7 12.5 25 5.6 0.5 3.9 2 1 2 4 4 4 0 SlyX Mod_r PF07200.13 KFP05330.1 - 6.3 6.9 14.4 1.1 9.4 5.5 2.5 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein 7tm_4 PF13853.6 KFP05331.1 - 5.8e-26 91.8 11.4 7e-26 91.6 11.4 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP05331.1 - 1.3e-15 57.5 9.6 2.5e-15 56.5 9.6 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4133 PF13571.6 KFP05331.1 - 1.3 9.4 5.3 3.2 8.2 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4133) Cadherin PF00028.17 KFP05332.1 - 1.4e-83 275.4 2.3 2.1e-18 66.6 0.0 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFP05332.1 - 2.1e-52 177.3 0.6 4.5e-52 176.2 0.6 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_3 PF16184.5 KFP05332.1 - 3.6e-07 30.2 4.7 0.091 12.8 0.0 4.9 5 0 0 5 5 5 2 Cadherin-like Cadherin_2 PF08266.12 KFP05332.1 - 8.4e-06 25.5 0.0 0.49 10.3 0.0 4.4 4 0 0 4 4 4 2 Cadherin-like Cadherin_4 PF17803.1 KFP05332.1 - 0.069 13.8 16.2 0.28 11.8 0.4 4.5 4 1 0 4 4 4 0 Bacterial cadherin-like domain Invasin_D3 PF09134.10 KFP05332.1 - 0.58 10.5 5.0 46 4.4 0.0 4.6 6 0 0 6 6 6 0 Invasin, domain 3 Big_9 PF17963.1 KFP05332.1 - 6.3 7.6 17.6 1.5 9.6 2.1 4.8 4 1 1 5 5 5 0 Bacterial Ig domain 7tm_1 PF00001.21 KFP05333.1 - 5.2e-36 124.3 34.3 1.3e-34 119.7 34.3 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP05333.1 - 8.2e-11 42.2 25.7 2.2e-10 40.7 17.6 2.5 1 1 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KFP05333.1 - 1.5e-10 40.9 34.0 2.9e-10 40.0 34.0 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP05333.1 - 0.00051 19.8 23.8 0.00051 19.8 23.8 2.8 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx UPF0489 PF12640.7 KFP05334.1 - 3.8e-59 199.9 0.1 7.2e-59 199.0 0.1 1.5 1 0 0 1 1 1 1 UPF0489 domain Ribonucleas_3_3 PF14622.6 KFP05335.1 - 5.4e-44 149.5 0.7 4.7e-24 85.0 0.0 3.2 3 0 0 3 3 3 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KFP05335.1 - 1e-42 145.0 0.3 1.1e-20 74.2 0.0 3.2 2 0 0 2 2 2 2 Ribonuclease III domain dsrm PF00035.26 KFP05335.1 - 5.7e-15 55.8 0.0 2.1e-14 54.0 0.0 2.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif Cadherin PF00028.17 KFP05336.1 - 5.6e-77 254.3 10.4 5.1e-19 68.5 0.1 5.4 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFP05336.1 - 1.4e-58 197.4 0.6 3e-58 196.3 0.6 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_3 PF16184.5 KFP05336.1 - 1.7e-08 34.5 6.2 0.079 13.0 0.1 5.4 5 0 0 5 5 5 3 Cadherin-like Cadherin_4 PF17803.1 KFP05336.1 - 3.3e-05 24.4 20.2 0.0088 16.6 0.5 4.7 4 0 0 4 4 4 2 Bacterial cadherin-like domain Cadherin_2 PF08266.12 KFP05336.1 - 6.5e-05 22.7 0.0 1.2 9.0 0.0 3.6 3 0 0 3 3 3 2 Cadherin-like ASFV_J13L PF05568.11 KFP05336.1 - 0.0062 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 African swine fever virus J13L protein Invasin_D3 PF09134.10 KFP05336.1 - 0.019 15.3 3.3 17 5.8 0.1 4.7 4 0 0 4 4 4 0 Invasin, domain 3 Stevor PF17410.2 KFP05336.1 - 0.035 13.7 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame 7TM_GPCR_Srw PF10324.9 KFP05336.1 - 0.1 11.9 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Big_9 PF17963.1 KFP05336.1 - 1.7 9.5 20.0 0.79 10.5 1.4 4.5 5 0 0 5 5 5 0 Bacterial Ig domain Peptidase_S8 PF00082.22 KFP05337.1 - 1.6e-50 172.1 1.0 2.1e-50 171.7 1.0 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KFP05337.1 - 5.8e-29 100.0 0.3 1.1e-28 99.1 0.3 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Proho_convert PF12177.8 KFP05337.1 - 2e-22 78.9 2.5 8.8e-22 76.8 2.5 2.2 1 0 0 1 1 1 1 Prohormone convertase enzyme S8_pro-domain PF16470.5 KFP05337.1 - 3.3e-14 53.4 4.0 6.9e-14 52.4 4.0 1.6 1 0 0 1 1 1 1 Peptidase S8 pro-domain Peptidase_S8_N PF16361.5 KFP05337.1 - 0.023 15.2 0.3 0.061 13.8 0.3 1.7 1 0 0 1 1 1 0 N-terminal of Subtilase family Calpain_inhib PF00748.19 KFP05340.1 - 1.1e-118 391.9 101.1 2.3e-37 128.5 19.5 6.1 5 1 1 6 6 6 5 Calpain inhibitor ERAP1_C PF11838.8 KFP05341.1 - 1e-69 235.5 0.0 1.4e-69 235.1 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KFP05341.1 - 1.2e-62 211.4 0.3 2.7e-62 210.2 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KFP05341.1 - 1.2e-44 152.7 0.4 2.4e-44 151.8 0.1 1.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 KFP05341.1 - 0.019 14.6 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily Pkinase PF00069.25 KFP05342.1 - 5.7e-72 242.3 0.0 1.2e-71 241.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP05342.1 - 3.8e-39 134.5 0.0 6.6e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KFP05342.1 - 1e-10 41.2 0.1 2.1e-10 40.2 0.1 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 KFP05342.1 - 3.5e-06 26.5 0.0 6.5e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFP05342.1 - 6.5e-05 23.0 0.1 0.038 13.9 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KFP05342.1 - 0.00017 21.0 0.2 0.00034 20.0 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFP05342.1 - 0.00081 18.4 0.1 0.0015 17.6 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KFP05342.1 - 0.017 14.7 0.1 0.042 13.5 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 KFP05342.1 - 0.039 13.5 0.1 0.12 11.9 0.1 1.8 1 0 0 1 1 1 0 Choline/ethanolamine kinase PAX PF00292.18 KFP05345.1 - 2.3e-75 250.5 0.7 3.7e-75 249.8 0.7 1.3 1 0 0 1 1 1 1 'Paired box' domain Pax2_C PF12403.8 KFP05345.1 - 7.1e-39 132.4 7.0 7.1e-39 132.4 7.0 2.1 2 0 0 2 2 2 1 Paired-box protein 2 C terminal HTH_32 PF13565.6 KFP05345.1 - 3.1e-06 27.7 0.2 0.0025 18.4 0.0 2.4 1 1 1 2 2 2 2 Homeodomain-like domain HTH_23 PF13384.6 KFP05345.1 - 4.2e-05 23.2 0.0 8.6e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFP05345.1 - 0.03 14.5 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_IS1 PF12759.7 KFP05345.1 - 0.058 13.0 0.1 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 InsA C-terminal domain Homeodomain PF00046.29 KFP05345.1 - 0.11 12.4 0.1 0.27 11.1 0.1 1.7 1 0 0 1 1 1 0 Homeodomain zf-CCHC PF00098.23 KFP05347.1 - 3.4e-11 42.7 46.0 3.5e-07 30.0 1.2 5.3 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_3 PF13917.6 KFP05347.1 - 0.00011 22.1 9.4 0.0019 18.1 3.8 5.1 1 1 4 5 5 5 3 Zinc knuckle zf-CCHC_2 PF13696.6 KFP05347.1 - 0.00021 21.1 40.5 0.0016 18.2 2.3 5.4 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_4 PF14392.6 KFP05347.1 - 0.074 12.8 34.6 0.15 11.8 0.6 5.2 4 1 1 5 5 5 0 Zinc knuckle 2-Hacid_dh_C PF02826.19 KFP05348.1 - 3.6e-60 202.4 0.0 4.3e-60 202.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KFP05348.1 - 1.5e-07 31.7 0.0 2.2e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh PF00389.30 KFP05348.1 - 4.7e-07 29.5 0.0 6e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 KFP05348.1 - 5.2e-07 30.2 0.0 9.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 KFP05348.1 - 0.0033 17.0 0.0 0.0043 16.6 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 KFP05348.1 - 0.031 14.3 0.0 0.11 12.5 0.0 1.9 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase MCM PF00493.23 KFP05348.1 - 0.072 12.2 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain ThiF PF00899.21 KFP05348.1 - 0.14 11.5 1.1 0.21 10.9 0.1 1.7 2 1 0 2 2 2 0 ThiF family BTB PF00651.31 KFP05349.1 - 1.6e-29 102.4 1.1 3e-29 101.5 1.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF3342 PF11822.8 KFP05349.1 - 0.008 16.4 0.2 0.016 15.4 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Rota_NS35 PF02509.14 KFP05349.1 - 0.066 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Rotavirus non-structural protein 35 GP79 PF17463.2 KFP05349.1 - 0.17 11.9 0.1 18 5.4 0.1 2.8 2 0 0 2 2 2 0 Gene product 79 RNA_pol_I_A49 PF06870.12 KFP05350.1 - 5.9e-91 305.2 0.0 2.1e-90 303.4 0.0 1.7 1 1 0 1 1 1 1 A49-like RNA polymerase I associated factor RgpF PF05045.12 KFP05350.1 - 0.17 10.7 0.1 0.22 10.2 0.1 1.1 1 0 0 1 1 1 0 Rhamnan synthesis protein F Mito_carr PF00153.27 KFP05351.1 - 4e-30 103.6 0.2 2.4e-09 37.0 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 KFP05352.1 - 2.8e-12 46.9 11.1 0.0004 21.1 0.8 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP05352.1 - 7.4e-05 23.0 0.0 7.1 7.0 0.1 4.3 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.6 KFP05352.1 - 0.042 13.8 0.1 7.9 6.4 0.0 2.9 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal CMD PF02627.20 KFP05353.1 - 2.7e-13 49.8 0.1 6.4e-12 45.4 0.0 2.1 1 1 1 2 2 2 1 Carboxymuconolactone decarboxylase family DUF1961 PF09224.11 KFP05353.1 - 0.02 14.3 0.1 0.029 13.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1961) PA26 PF04636.13 KFP05353.1 - 0.023 13.7 0.0 0.028 13.3 0.0 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) tRNA_m1G_MT PF01746.21 KFP05354.1 - 4.1e-23 82.1 0.0 4.9e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase DUF543 PF04418.12 KFP05354.1 - 0.17 11.9 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF543) Opiods_neuropep PF01160.18 KFP05355.1 - 4.6e-17 61.8 1.7 6.8e-17 61.3 1.7 1.3 1 0 0 1 1 1 1 Vertebrate endogenous opioids neuropeptide Op_neuropeptide PF08035.11 KFP05355.1 - 0.0072 16.2 40.4 0.81 9.6 0.2 7.2 7 0 0 7 7 7 6 Opioids neuropeptide Amdo_NSP PF12475.8 KFP05355.1 - 0.051 13.7 0.3 48 4.2 0.0 3.9 5 0 0 5 5 5 0 Amdovirus non-structural protein RVT_1 PF00078.27 KFP05356.1 - 1e-13 51.3 0.0 2.8e-13 49.9 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFP05356.1 - 0.0054 16.7 0.0 0.014 15.5 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase WD40_like PF17005.5 KFP05357.1 - 0.00024 20.5 0.0 0.19 11.0 0.0 2.1 2 0 0 2 2 2 2 WD40-like domain WD40 PF00400.32 KFP05357.1 - 0.00026 21.7 3.7 0.8 10.7 1.0 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP05357.1 - 0.024 14.9 0.0 5.7 7.3 0.0 3.2 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain RVT_1 PF00078.27 KFP05358.1 - 3.7e-05 23.4 0.0 4.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.11 KFP05358.1 - 0.18 11.5 0.6 0.27 10.9 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) RNF111_N PF15303.6 KFP05359.1 - 1.8e-38 132.9 31.2 4.4e-38 131.6 31.2 1.7 1 1 0 1 1 1 1 E3 ubiquitin-protein ligase Arkadia N-terminus Presenilin PF01080.17 KFP05359.1 - 6.1 5.5 5.5 8.7 5.0 5.5 1.4 1 0 0 1 1 1 0 Presenilin ATP-synt_ab PF00006.25 KFP05360.1 - 2e-74 249.9 0.0 3.1e-74 249.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KFP05360.1 - 3.4e-47 159.9 2.3 5.5e-47 159.2 2.3 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KFP05360.1 - 1.2e-17 64.2 1.8 3e-17 62.9 1.8 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF4142 PF13628.6 KFP05360.1 - 0.00014 22.1 2.4 0.00025 21.3 2.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4142) E3_UFM1_ligase PF09743.9 KFP05361.1 - 3e-107 358.3 0.3 3e-107 358.3 0.3 2.1 3 0 0 3 3 3 1 E3 UFM1-protein ligase 1 HTH_9 PF08221.11 KFP05361.1 - 0.09 12.9 0.0 1.6 8.9 0.0 3.0 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF4140 PF13600.6 KFP05361.1 - 0.18 12.2 7.4 2.4 8.6 0.4 3.1 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Tn7_Tnp_TnsA_C PF08721.11 KFP05361.1 - 0.97 10.1 6.7 5.6 7.7 0.0 4.4 5 1 1 6 6 6 0 TnsA endonuclease C terminal LIM PF00412.22 KFP05362.1 - 1.6e-47 159.6 63.7 3.8e-13 49.4 6.8 5.1 5 0 0 5 5 5 5 LIM domain 7tm_1 PF00001.21 KFP05363.1 - 3.1e-50 170.9 23.6 4.6e-50 170.4 23.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP05363.1 - 7.8e-07 28.7 25.1 1.5e-06 27.8 25.1 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP05363.1 - 0.0014 18.4 9.4 0.0014 18.4 9.4 3.0 3 0 0 3 3 3 1 Olfactory receptor DUF5527 PF17665.1 KFP05363.1 - 0.044 13.3 0.7 0.11 12.1 0.7 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5527) UPF0240 PF06784.11 KFP05364.1 - 7.9e-37 127.0 0.2 8.7e-37 126.8 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0240) Kelch_1 PF01344.25 KFP05365.1 - 3.5e-35 119.3 14.3 7.8e-08 31.8 0.1 6.8 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KFP05365.1 - 3.1e-33 113.0 8.7 1.6e-06 28.2 0.0 7.4 4 2 2 6 6 6 5 Kelch motif BTB PF00651.31 KFP05365.1 - 8.5e-27 93.6 2.0 1.9e-26 92.5 0.3 2.3 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.6 KFP05365.1 - 8.3e-17 61.0 3.4 0.0017 18.6 0.0 6.9 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KFP05365.1 - 1.3e-16 60.3 2.2 0.12 12.4 0.0 6.7 6 1 0 6 6 6 4 Galactose oxidase, central domain BACK PF07707.15 KFP05365.1 - 2.6e-16 59.6 1.8 6.9e-16 58.2 1.8 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 KFP05365.1 - 6.4e-16 57.6 3.3 0.033 14.2 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 KFP05365.1 - 4.7e-14 52.0 2.4 0.12 12.4 0.1 6.3 6 0 0 6 6 6 4 Kelch motif PQQ_3 PF13570.6 KFP05365.1 - 0.034 14.6 1.0 49 4.6 0.0 4.7 5 0 0 5 5 5 0 PQQ-like domain Rubis-subs-bind PF09273.11 KFP05365.1 - 0.23 12.2 1.8 1.6 9.4 0.0 2.6 3 0 0 3 3 3 0 Rubisco LSMT substrate-binding Pou PF00157.17 KFP05367.1 - 4.8e-38 129.0 0.3 9.2e-38 128.1 0.3 1.5 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KFP05367.1 - 1e-19 70.1 0.3 2.4e-19 68.9 0.3 1.6 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 KFP05367.1 - 0.00014 22.1 0.0 0.023 15.1 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain Homeobox_KN PF05920.11 KFP05367.1 - 0.003 17.4 0.0 0.007 16.3 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain DUF521 PF04412.13 KFP05367.1 - 0.12 11.1 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) LRR_4 PF12799.7 KFP05368.1 - 3.2e-10 40.1 12.0 0.0054 17.1 0.0 7.1 4 1 4 8 8 8 5 Leucine Rich repeats (2 copies) F-box PF00646.33 KFP05368.1 - 4e-08 32.9 0.4 4e-08 32.9 0.4 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KFP05368.1 - 6.4e-08 32.4 2.8 2.6e-07 30.4 2.8 2.2 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 KFP05368.1 - 0.00033 20.5 7.7 3.7 7.8 0.1 6.3 6 0 0 6 6 6 1 Leucine Rich repeat LRR_9 PF14580.6 KFP05368.1 - 0.00062 19.3 0.2 0.48 9.9 0.1 2.5 2 0 0 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KFP05368.1 - 0.0013 18.4 5.9 0.55 10.0 0.0 4.6 3 2 2 5 5 5 3 Leucine rich repeat F-box_4 PF15966.5 KFP05368.1 - 0.0021 17.9 0.1 0.0063 16.4 0.1 1.9 1 0 0 1 1 1 1 F-box LRR_1 PF00560.33 KFP05368.1 - 0.0051 17.2 18.0 2.3 9.1 0.2 7.4 7 1 0 7 7 7 2 Leucine Rich Repeat Adeno_E3_CR2 PF02439.15 KFP05368.1 - 0.26 11.1 0.9 0.5 10.2 0.9 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 GST_N_4 PF17172.4 KFP05369.1 - 6.3e-32 110.3 0.0 1.1e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KFP05369.1 - 4.2e-19 68.1 0.0 7.5e-19 67.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KFP05369.1 - 1.7e-14 54.2 0.1 4.2e-14 52.9 0.0 1.6 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 KFP05369.1 - 5.7e-05 23.1 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFP05369.1 - 0.0021 18.4 0.0 0.037 14.4 0.0 2.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Methyltransf_23 PF13489.6 KFP05370.1 - 5.5e-21 75.1 0.0 9e-21 74.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP05370.1 - 1.1e-18 67.7 0.0 1.7e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP05370.1 - 2.2e-15 57.2 0.0 3.5e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP05370.1 - 2e-14 54.1 0.0 3.5e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP05370.1 - 6.1e-13 48.8 0.0 8.4e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KFP05370.1 - 2.4e-08 33.6 0.0 3.1e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KFP05370.1 - 9.4e-07 28.5 0.0 1.3e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KFP05370.1 - 5.2e-05 22.7 0.0 8.6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 KFP05370.1 - 6.4e-05 22.7 0.0 9.2e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 KFP05370.1 - 8.6e-05 22.2 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 KFP05370.1 - 0.00099 18.9 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_9 PF08003.11 KFP05370.1 - 0.001 18.0 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.14 KFP05370.1 - 0.002 17.6 0.0 0.0028 17.1 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_PK PF05891.12 KFP05370.1 - 0.005 16.4 0.0 0.0066 16.0 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_32 PF13679.6 KFP05370.1 - 0.062 13.3 0.1 0.15 12.0 0.0 1.6 1 1 1 2 2 2 0 Methyltransferase domain PNISR PF15996.5 KFP05371.1 - 3.2e-53 181.0 24.7 3.2e-53 181.0 24.7 6.1 2 2 3 5 5 5 1 Arginine/serine-rich protein PNISR UCH PF00443.29 KFP05372.1 - 7.7e-46 156.7 1.9 1.2e-45 156.0 1.9 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFP05372.1 - 2.1e-17 63.2 10.0 2.1e-17 63.2 10.0 2.6 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein THOC7 PF05615.13 KFP05372.1 - 0.037 14.3 1.0 0.037 14.3 1.0 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 GIT1_C PF12205.8 KFP05372.1 - 0.18 11.9 1.5 0.65 10.1 1.5 1.9 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term Rhodanese PF00581.20 KFP05373.1 - 1.3e-07 32.1 0.0 1.4e-07 32.0 0.0 1.0 1 0 0 1 1 1 1 Rhodanese-like domain HK PF02110.15 KFP05373.1 - 0.067 12.6 0.0 0.072 12.5 0.0 1.1 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family Cyclin_N PF00134.23 KFP05374.1 - 2.4e-14 53.2 3.7 7.9e-13 48.3 0.7 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KFP05374.1 - 5.9e-07 29.8 0.3 2.2e-06 28.0 0.3 2.0 1 1 0 1 1 1 1 Cyclin C-terminal domain TFIIB PF00382.19 KFP05374.1 - 0.007 16.4 0.1 0.11 12.6 0.0 2.2 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C PF02984.19 KFP05374.1 - 0.0081 16.2 0.7 0.065 13.3 0.1 2.5 2 1 1 3 3 3 1 Cyclin, C-terminal domain SIM_C PF06621.12 KFP05375.1 - 1e-109 367.1 14.7 1.5e-109 366.6 14.7 1.2 1 0 0 1 1 1 1 Single-minded protein C-terminus PAS_3 PF08447.12 KFP05375.1 - 1.8e-22 79.5 1.6 4.6e-15 55.7 0.0 3.2 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.6 KFP05375.1 - 1.9e-16 60.2 0.1 2.4e-10 40.6 0.0 2.8 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 KFP05375.1 - 9.3e-16 57.8 0.0 6.9e-12 45.4 0.0 2.7 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 KFP05375.1 - 6.1e-06 26.1 2.1 5.4e-05 23.1 0.7 2.6 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 KFP05375.1 - 1.1e-05 25.6 0.0 0.017 15.3 0.0 2.7 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 KFP05375.1 - 1.2e-05 25.5 0.0 0.03 14.6 0.0 2.8 3 0 0 3 3 3 2 PAS fold Sec63 PF02889.16 KFP05376.1 - 4e-153 507.9 0.2 5.4e-83 278.1 0.1 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KFP05376.1 - 3e-52 176.9 4.2 1.9e-26 92.9 0.5 3.2 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 KFP05376.1 - 1.2e-25 90.4 1.4 1.1e-11 45.1 0.1 2.8 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFP05376.1 - 2.9e-12 46.9 0.3 4.3e-07 30.3 0.0 3.7 3 1 0 3 3 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFP05376.1 - 6.8e-06 26.4 3.4 0.041 14.1 0.1 3.9 3 1 0 3 3 3 2 AAA domain T2SSE PF00437.20 KFP05376.1 - 0.00017 20.8 0.0 0.64 9.0 0.0 3.2 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA PF00004.29 KFP05376.1 - 0.00082 19.8 0.4 0.81 10.1 0.0 3.6 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KFP05376.1 - 0.0012 19.2 0.5 0.12 12.7 0.2 2.8 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 KFP05376.1 - 0.0025 17.3 0.1 1.8 8.0 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_7 PF12775.7 KFP05376.1 - 0.0058 16.2 0.0 3.3 7.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 KFP05376.1 - 0.033 13.9 0.7 0.38 10.5 0.0 3.0 4 0 0 4 4 4 0 IstB-like ATP binding protein UvrD-helicase PF00580.21 KFP05376.1 - 0.24 10.9 0.9 1.6 8.2 0.1 2.5 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain DUF5525 PF17663.1 KFP05377.1 - 1.1e-69 235.7 2.1 1.2e-69 235.6 2.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5525) Flavoprotein PF02441.19 KFP05378.1 - 3.3e-48 163.4 0.0 3.6e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein SCAMP PF04144.13 KFP05379.1 - 6e-70 235.1 16.3 7.1e-70 234.8 16.3 1.1 1 0 0 1 1 1 1 SCAMP family Alba PF01918.21 KFP05380.1 - 1.5e-19 69.6 0.8 1.9e-19 69.2 0.8 1.1 1 0 0 1 1 1 1 Alba COX5A PF02284.16 KFP05381.1 - 5.1e-47 158.1 0.0 5.8e-47 157.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va PMI_typeI PF01238.21 KFP05382.1 - 3.3e-128 428.0 0.0 4.1e-128 427.7 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I SCAMP PF04144.13 KFP05383.1 - 4.1e-69 232.3 16.4 5e-69 232.1 16.4 1.1 1 0 0 1 1 1 1 SCAMP family OmpH PF03938.14 KFP05383.1 - 0.22 11.8 3.5 0.14 12.5 1.4 1.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) UPF0542 PF15086.6 KFP05383.1 - 0.44 10.5 0.0 0.44 10.5 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 KfrA_N PF11740.8 KFP05383.1 - 8.8 7.0 15.0 0.62 10.8 10.2 1.5 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Pkinase PF00069.25 KFP05384.1 - 5.7e-66 222.6 0.0 8.1e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP05384.1 - 3.3e-39 134.7 0.0 4.6e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MIT PF04212.18 KFP05384.1 - 1.4e-31 108.4 15.3 9.6e-20 70.4 3.0 3.0 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain Kdo PF06293.14 KFP05384.1 - 3.3e-05 23.3 0.1 6.8e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFP05384.1 - 0.01 15.4 0.0 0.031 13.9 0.0 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 KFP05384.1 - 0.05 13.5 0.1 0.05 13.5 0.1 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family Synaphin PF05835.12 KFP05385.1 - 6.3e-48 162.7 11.4 7.5e-48 162.4 11.4 1.1 1 0 0 1 1 1 1 Synaphin protein Pkinase_Tyr PF07714.17 KFP05386.1 - 3.7e-78 262.4 0.2 1.3e-59 201.6 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFP05386.1 - 2.3e-39 135.4 0.0 1.5e-25 90.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain SH2 PF00017.24 KFP05386.1 - 5.2e-24 84.1 0.1 1.1e-23 83.1 0.1 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFP05386.1 - 1.4e-13 50.2 0.0 2.6e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP05386.1 - 4.1e-08 32.9 0.0 9.9e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP05386.1 - 1.7e-06 27.6 0.0 3.5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain APH PF01636.23 KFP05386.1 - 0.0052 16.7 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFP05386.1 - 0.047 13.0 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like SH3_3 PF08239.11 KFP05386.1 - 0.16 12.3 0.1 0.4 11.0 0.1 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain Edc3_linker PF16598.5 KFP05387.1 - 4.6e-43 145.8 3.1 4.6e-43 145.8 3.1 1.7 2 0 0 2 2 2 1 Linker region of enhancer of mRNA-decapping protein 3 YjeF_N PF03853.15 KFP05387.1 - 8e-20 71.4 0.0 1.3e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 KFP05387.1 - 3.9e-15 56.6 0.0 7.9e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 FDF domain LSM14 PF12701.7 KFP05387.1 - 6.4e-10 39.0 0.0 1.7e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Scd6-like Sm domain DUF5096 PF17019.5 KFP05387.1 - 0.016 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5096) Pkinase PF00069.25 KFP05388.1 - 1.6e-45 155.6 0.1 2e-45 155.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP05388.1 - 3.3e-22 79.0 0.1 1.1e-20 74.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase SR-25 PF10500.9 KFP05388.1 - 5.8 6.5 22.7 13 5.3 22.7 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ARID PF01388.21 KFP05389.1 - 6.2e-14 52.4 0.0 1.1e-13 51.7 0.0 1.4 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF1451 PF07295.11 KFP05389.1 - 0.11 12.6 0.3 0.16 12.0 0.3 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Yae1_N PF09811.9 KFP05390.1 - 5.9e-11 41.9 32.6 1e+02 2.7 32.6 3.4 1 1 0 1 1 1 1 Essential protein Yae1, N terminal RUN PF02759.19 KFP05391.1 - 5.6e-05 23.1 0.1 0.00011 22.1 0.0 1.5 2 0 0 2 2 2 1 RUN domain zf-RING_9 PF13901.6 KFP05392.1 - 6.7e-58 196.1 1.5 1.1e-57 195.3 1.5 1.4 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon PH PF00169.29 KFP05392.1 - 6.2e-08 33.1 0.0 0.0014 19.1 0.0 2.5 2 0 0 2 2 2 2 PH domain zf-RRN7 PF11781.8 KFP05392.1 - 0.00057 19.5 1.5 0.044 13.5 0.5 2.7 2 0 0 2 2 2 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 PH_13 PF16652.5 KFP05392.1 - 0.019 14.8 0.0 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain FYVE_2 PF02318.16 KFP05392.1 - 0.79 10.0 3.6 2.8 8.2 0.3 2.6 2 0 0 2 2 2 0 FYVE-type zinc finger Prok-RING_2 PF14445.6 KFP05392.1 - 1.4 9.2 9.7 1.1 9.5 0.6 3.5 3 1 1 4 4 4 0 Prokaryotic RING finger family 2 GCIP PF13324.6 KFP05393.1 - 2.2e-07 30.8 0.0 2.4e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting FAM163 PF15069.6 KFP05393.1 - 0.00048 20.6 0.1 0.00054 20.5 0.1 1.2 1 0 0 1 1 1 1 FAM163 family Cadherin_C_2 PF16492.5 KFP05393.1 - 0.0061 17.3 0.0 0.0089 16.8 0.0 1.4 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal Ribosomal_S19e PF01090.19 KFP05394.1 - 3.7e-20 72.0 0.2 5.6e-12 45.5 0.0 2.0 2 0 0 2 2 2 2 Ribosomal protein S19e HTH_12 PF08461.10 KFP05394.1 - 0.023 14.6 0.1 0.035 14.0 0.1 1.3 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain ANF_receptor PF01094.28 KFP05395.1 - 8.3e-83 278.4 0.0 9.7e-83 278.2 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.9 KFP05395.1 - 4.1e-26 91.4 0.1 2.7e-25 88.8 0.0 2.3 3 0 0 3 3 3 1 Ligated ion channel L-glutamate- and glycine-binding site Peripla_BP_6 PF13458.6 KFP05395.1 - 2e-09 37.6 0.0 2.9e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein NUDE_C PF04880.13 KFP05396.1 - 5.4e-46 157.3 14.0 6e-46 157.1 0.7 2.4 2 1 0 2 2 2 1 NUDE protein, C-terminal conserved region PRKG1_interact PF15898.5 KFP05396.1 - 0.0048 17.8 8.0 0.0048 17.8 8.0 2.9 1 1 1 3 3 3 2 cGMP-dependent protein kinase interacting domain HALZ PF02183.18 KFP05396.1 - 0.022 15.0 2.4 0.022 15.0 2.4 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF5576 PF17739.1 KFP05396.1 - 0.029 14.5 0.4 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5576) bZIP_2 PF07716.15 KFP05396.1 - 0.043 13.9 2.1 0.043 13.9 2.1 4.9 2 2 3 5 5 5 0 Basic region leucine zipper DUF1664 PF07889.12 KFP05396.1 - 0.083 12.9 9.9 0.078 13.0 4.7 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 KFP05396.1 - 0.089 12.2 22.9 0.14 11.6 22.9 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 ATG16 PF08614.11 KFP05396.1 - 0.092 13.0 34.0 0.28 11.4 6.3 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Rootletin PF15035.6 KFP05396.1 - 0.092 12.8 31.7 0.25 11.4 12.9 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion HAD_SAK_1 PF10307.9 KFP05396.1 - 0.13 12.1 4.7 0.18 11.6 0.9 2.1 2 0 0 2 2 2 0 HAD domain family 1 in Swiss Army Knife RNA repair proteins TPR_MLP1_2 PF07926.12 KFP05396.1 - 0.17 12.0 33.6 0.053 13.6 8.8 3.5 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Fzo_mitofusin PF04799.13 KFP05396.1 - 0.99 8.9 15.8 0.078 12.5 5.2 3.0 1 1 3 4 4 4 0 fzo-like conserved region KxDL PF10241.9 KFP05396.1 - 1.2 9.4 13.8 0.26 11.6 4.7 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein FlaC_arch PF05377.11 KFP05396.1 - 1.8 9.0 8.6 4.3 7.8 0.9 4.0 2 1 1 4 4 4 0 Flagella accessory protein C (FlaC) YabA PF06156.13 KFP05396.1 - 2.4 8.8 20.2 4.6 7.9 6.4 3.3 1 1 1 2 2 2 0 Initiation control protein YabA DUF5595 PF18077.1 KFP05396.1 - 2.5 8.2 17.4 0.091 12.9 3.0 3.6 2 2 2 4 4 4 0 Domain of unknown function (DUF5595) BST2 PF16716.5 KFP05396.1 - 4.2 8.0 24.9 1.3 9.6 13.4 2.9 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 YojJ PF10372.9 KFP05396.1 - 4.7 7.4 7.4 1.8 8.7 1.1 2.9 2 1 1 3 3 3 0 Bacterial membrane-spanning protein N-terminus Lectin_N PF03954.14 KFP05396.1 - 5 6.9 10.8 1.4 8.7 3.8 3.0 2 1 2 4 4 4 0 Hepatic lectin, N-terminal domain ADIP PF11559.8 KFP05396.1 - 9.8 6.2 28.4 1.2 9.2 9.8 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding HCO3_cotransp PF00955.21 KFP05398.1 - 1.4e-216 720.2 7.4 1.8e-216 719.9 7.4 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 KFP05398.1 - 5.4e-84 282.2 0.0 8e-84 281.6 0.0 1.3 1 0 0 1 1 1 1 Band 3 cytoplasmic domain PTS_EIIA_2 PF00359.22 KFP05398.1 - 0.12 12.2 0.0 0.3 11.0 0.0 1.6 2 0 0 2 2 2 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 MFS_MOT1 PF16983.5 KFP05398.1 - 0.96 9.9 9.4 0.94 9.9 1.3 3.4 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily DUF4200 PF13863.6 KFP05399.1 - 2e-21 76.6 29.1 2e-21 76.6 29.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) V-set PF07686.17 KFP05400.1 - 0.00016 21.8 0.0 0.00024 21.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain ComGF PF15980.5 KFP05400.1 - 0.019 15.3 0.0 0.039 14.3 0.0 1.5 1 0 0 1 1 1 0 Putative Competence protein ComGF Septin PF00735.18 KFP05401.1 - 1.8e-111 372.0 2.9 2e-111 371.8 2.9 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFP05401.1 - 3.9e-10 39.8 0.1 8.9e-10 38.7 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP05401.1 - 3.9e-07 30.1 1.3 3.6e-06 27.0 0.6 2.3 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KFP05401.1 - 9e-06 25.3 1.1 0.00013 21.6 0.2 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KFP05401.1 - 1.3e-05 24.7 0.1 2.3e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KFP05401.1 - 2.7e-05 24.3 2.1 0.0071 16.4 0.9 2.4 1 1 1 2 2 2 2 Dynamin family Roc PF08477.13 KFP05401.1 - 5e-05 23.5 0.1 0.00012 22.3 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP05401.1 - 0.00011 21.9 0.2 0.00039 20.1 0.0 2.0 2 0 0 2 2 2 1 Ras family AAA_16 PF13191.6 KFP05401.1 - 0.00074 19.9 0.0 0.0015 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KFP05401.1 - 0.0013 18.5 0.2 0.01 15.6 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KFP05401.1 - 0.0019 18.5 0.0 0.0039 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain IIGP PF05049.13 KFP05401.1 - 0.0021 17.2 0.9 0.022 13.8 0.0 2.4 3 0 0 3 3 3 1 Interferon-inducible GTPase (IIGP) G-alpha PF00503.20 KFP05401.1 - 0.0021 17.3 2.0 0.0045 16.2 1.2 1.7 1 1 0 1 1 1 1 G-protein alpha subunit ABC_tran PF00005.27 KFP05401.1 - 0.0022 18.5 1.3 0.004 17.7 0.8 1.7 1 1 0 2 2 2 1 ABC transporter NB-ARC PF00931.22 KFP05401.1 - 0.0074 15.5 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain FtsK_SpoIIIE PF01580.18 KFP05401.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Gtr1_RagA PF04670.12 KFP05401.1 - 0.012 14.9 0.2 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 KFP05401.1 - 0.015 15.1 0.3 0.18 11.5 0.1 2.3 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KFP05401.1 - 0.015 14.8 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 KFP05401.1 - 0.016 14.9 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 KFP05401.1 - 0.018 14.8 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein tRNA_synthFbeta PF17759.1 KFP05401.1 - 0.025 14.0 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Phenylalanyl tRNA synthetase beta chain CLM domain Arf PF00025.21 KFP05401.1 - 0.036 13.5 0.1 0.075 12.5 0.1 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_14 PF13173.6 KFP05401.1 - 0.046 13.7 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KFP05401.1 - 0.053 13.0 0.2 0.16 11.5 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Ploopntkinase3 PF18751.1 KFP05401.1 - 0.059 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Sigma54_activat PF00158.26 KFP05401.1 - 0.066 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KFP05401.1 - 0.13 12.6 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase TNRC6-PABC_bdg PF16608.5 KFP05402.1 - 2.6e-102 342.5 36.0 2.3e-75 254.0 7.5 8.5 7 2 2 9 9 9 2 TNRC6-PABC binding domain M_domain PF12938.7 KFP05402.1 - 7e-67 225.8 42.6 7e-67 225.8 42.6 6.6 4 1 5 9 9 9 1 M domain of GW182 Ago_hook PF10427.9 KFP05402.1 - 1.7e-20 74.2 29.0 1.7e-20 74.2 29.0 11.5 3 2 6 9 9 9 1 Argonaute hook UBA PF00627.31 KFP05402.1 - 4.7e-06 26.4 0.1 9.3e-06 25.4 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RRM_1 PF00076.22 KFP05402.1 - 0.00014 21.6 0.0 0.00024 20.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP05402.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF2748 PF10871.8 KFP05402.1 - 0.56 8.8 4.6 1.5 7.4 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2748) THOC7 PF05615.13 KFP05402.1 - 3.2 8.0 8.2 5.9 7.2 8.2 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 Ras PF00071.22 KFP05404.1 - 4.6e-39 133.6 0.0 5.3e-39 133.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP05404.1 - 3.7e-16 59.4 0.0 5e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP05404.1 - 1.8e-09 37.3 0.0 2.1e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFP05404.1 - 1.8e-05 24.3 0.0 2.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KFP05404.1 - 3.2e-05 23.9 0.2 0.11 12.4 0.0 2.1 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFP05404.1 - 0.00015 21.9 0.0 0.00022 21.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP05404.1 - 0.00015 21.4 0.0 0.0093 15.5 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFP05404.1 - 0.013 15.9 0.1 0.026 14.9 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KFP05404.1 - 0.021 14.8 0.0 0.089 12.7 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 KFP05404.1 - 0.026 14.8 0.2 0.17 12.2 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFP05404.1 - 0.05 13.1 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AP1AR PF15745.5 KFP05404.1 - 0.072 12.7 0.1 0.091 12.4 0.1 1.1 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein G-alpha PF00503.20 KFP05404.1 - 0.087 12.0 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit ATPase_2 PF01637.18 KFP05404.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PRELI PF04707.14 KFP05405.1 - 8.5e-52 175.1 0.4 1.3e-51 174.5 0.4 1.3 1 0 0 1 1 1 1 PRELI-like family CRAL_TRIO PF00650.20 KFP05405.1 - 4.9e-41 140.1 0.0 8.5e-41 139.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFP05405.1 - 7.9e-06 26.0 0.1 2e-05 24.7 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Glyco_transf_18 PF15024.6 KFP05407.1 - 5.1e-267 887.0 0.0 6.1e-267 886.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 18 UL42 PF17638.2 KFP05407.1 - 1.5 8.8 5.2 3.8 7.5 5.2 1.6 1 0 0 1 1 1 0 HCMV UL42 RRM_1 PF00076.22 KFP05408.1 - 7.8e-18 64.1 0.0 1.2e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFP05408.1 - 0.019 15.0 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Methyltransf_16 PF10294.9 KFP05409.1 - 2.9e-07 30.4 0.0 0.00011 21.9 0.0 2.1 1 1 1 2 2 2 2 Lysine methyltransferase JmjC PF02373.22 KFP05410.1 - 7.9e-30 103.6 0.0 1.6e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KFP05410.1 - 1.9e-18 67.1 0.1 4.3e-18 65.9 0.1 1.5 1 1 0 1 1 1 1 Cupin-like domain SR-25 PF10500.9 KFP05410.1 - 0.016 14.8 12.1 0.03 13.9 12.1 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 KFP05410.1 - 0.13 10.4 14.2 0.17 9.9 14.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Glyco_transf_29 PF00777.18 KFP05411.1 - 8.9e-70 235.2 0.0 1e-69 234.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Globin PF00042.22 KFP05412.1 - 1.7e-24 86.5 0.1 2.6e-24 85.9 0.1 1.3 1 0 0 1 1 1 1 Globin DUF592 PF04574.13 KFP05412.1 - 0.075 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF592) Acetyltransf_1 PF00583.25 KFP05413.1 - 5.6e-15 55.6 0.0 7e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFP05413.1 - 1.7e-08 34.5 0.0 2.2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFP05413.1 - 2.6e-06 27.8 0.0 3.8e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFP05413.1 - 0.03 14.4 0.0 0.083 13.0 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain UQ_con PF00179.26 KFP05414.1 - 2e-23 82.6 0.0 5e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DAGK_cat PF00781.24 KFP05415.1 - 1.2e-19 70.1 0.0 1.5e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Pribosyl_synth PF14572.6 KFP05416.1 - 8.5e-101 335.6 0.6 8.5e-101 335.6 0.6 1.6 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KFP05416.1 - 2.3e-38 130.7 0.2 4.7e-38 129.7 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KFP05416.1 - 6.2e-06 25.8 0.1 1.6e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain DUF4795 PF16043.5 KFP05417.1 - 0.025 14.2 2.3 0.025 14.2 2.3 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4795) NPV_P10 PF05531.12 KFP05417.1 - 9.2 6.8 10.6 2.9 8.4 0.1 3.6 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein zf-C3HC4_3 PF13920.6 KFP05418.1 - 4e-08 33.0 6.8 9.3e-08 31.8 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP05418.1 - 0.088 12.7 9.4 0.22 11.4 9.4 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Forkhead PF00250.18 KFP05419.1 - 1.2e-36 124.8 0.0 2.1e-36 124.0 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Exo70 PF03081.15 KFP05420.1 - 1.9e-84 283.9 2.4 1.9e-84 283.9 2.4 1.7 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Sec34 PF04136.15 KFP05420.1 - 0.0031 17.4 2.7 0.011 15.6 2.2 2.2 2 0 0 2 2 2 1 Sec34-like family Vps52 PF04129.12 KFP05420.1 - 0.015 14.1 4.4 0.25 10.1 1.3 2.3 2 0 0 2 2 2 0 Vps52 / Sac2 family DUF4404 PF14357.6 KFP05420.1 - 0.054 14.1 0.2 0.93 10.2 0.1 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) MTD PF01993.18 KFP05420.1 - 0.072 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase Sec20 PF03908.13 KFP05420.1 - 0.44 10.5 2.5 1.1 9.2 1.3 2.4 3 0 0 3 3 3 0 Sec20 COG6 PF06419.11 KFP05420.1 - 0.49 8.5 10.6 0.4 8.8 1.5 2.2 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 COG5 PF10392.9 KFP05420.1 - 2.3 8.4 10.2 0.038 14.2 1.7 2.5 3 0 0 3 3 3 0 Golgi transport complex subunit 5 7tm_1 PF00001.21 KFP05421.1 - 3.7e-54 183.8 21.4 4.4e-54 183.6 21.4 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFP05421.1 - 1e-12 48.0 17.9 3.2e-11 43.1 17.9 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 KFP05421.1 - 7.2e-11 41.9 19.7 8.5e-11 41.7 19.7 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP05421.1 - 2.5e-06 27.4 19.3 8.7e-06 25.7 19.3 1.7 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP05421.1 - 2.8e-05 23.9 22.1 3e-05 23.8 21.1 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx SecG PF03840.14 KFP05421.1 - 0.028 14.5 2.6 5.3 7.2 0.0 3.5 3 0 0 3 3 3 0 Preprotein translocase SecG subunit SRP68 PF16969.5 KFP05422.1 - 4.6e-155 517.8 13.4 5.2e-155 517.6 13.4 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 TPR_6 PF13174.6 KFP05422.1 - 0.0011 19.4 3.1 0.85 10.4 0.2 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFP05422.1 - 0.024 14.5 2.3 1.1 9.1 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF5340 PF17275.2 KFP05422.1 - 0.22 11.7 6.1 0.8 9.9 0.3 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5340) FRP PF18032.1 KFP05422.1 - 0.22 12.1 2.4 2.6 8.7 0.1 2.9 2 0 0 2 2 2 0 Photoprotection regulator fluorescence recovery protein TPR_2 PF07719.17 KFP05422.1 - 0.4 10.9 11.5 0.43 10.8 0.3 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat GCOM2 PF15328.6 KFP05422.1 - 0.79 10.1 6.3 0.24 11.7 2.2 2.1 2 0 0 2 2 2 0 Putative GRINL1B complex locus protein 2 Plectin PF00681.20 KFP05423.1 - 3.8e-49 164.3 0.6 4.5e-13 48.9 0.0 7.6 5 1 2 7 7 7 6 Plectin repeat SH3_10 PF17902.1 KFP05423.1 - 8.1e-20 70.7 0.1 2.8e-19 68.9 0.1 2.0 1 0 0 1 1 1 1 SH3 domain ADH_N_2 PF16884.5 KFP05423.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase DUF4810 PF16068.5 KFP05423.1 - 6.6 7.4 7.1 13 6.4 0.1 5.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4810) Ten1_2 PF15490.6 KFP05424.1 - 5.2e-44 148.8 0.0 5.7e-44 148.6 0.0 1.0 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit ACOX PF01756.19 KFP05425.1 - 3.4e-69 232.0 0.8 8e-69 230.8 0.8 1.6 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KFP05425.1 - 4.2e-26 91.9 0.9 1.1e-25 90.6 0.1 2.1 3 0 0 3 3 3 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KFP05425.1 - 7.5e-12 45.3 0.0 1.4e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KFP05425.1 - 0.0082 16.4 0.0 0.026 14.7 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain QRPTase_C PF01729.19 KFP05426.1 - 3.9e-23 82.1 0.0 4.2e-23 82.0 0.0 1.0 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain PIRT PF15099.6 KFP05427.1 - 4.2e-68 226.9 2.5 4.7e-68 226.8 2.5 1.0 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family TMEM100 PF16311.5 KFP05427.1 - 9e-05 22.1 0.1 9.6e-05 22.0 0.1 1.1 1 0 0 1 1 1 1 Transmembrane protein 100 Phage_holin_3_6 PF07332.11 KFP05427.1 - 0.0081 16.2 0.1 0.011 15.8 0.1 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III YajC PF02699.15 KFP05427.1 - 0.013 15.4 0.4 0.027 14.3 0.4 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit Claudin_2 PF13903.6 KFP05427.1 - 0.023 14.4 0.1 0.026 14.3 0.1 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF872 PF05915.12 KFP05427.1 - 0.058 13.6 0.0 0.077 13.2 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) SdpI PF13630.6 KFP05427.1 - 0.096 12.8 2.6 0.71 10.0 2.6 2.0 1 1 0 1 1 1 0 SdpI/YhfL protein family Neurensin PF14927.6 KFP05427.1 - 0.2 11.4 1.6 2.1 8.0 0.1 2.1 1 1 1 2 2 2 0 Neurensin EphA2_TM PF14575.6 KFP05427.1 - 1.2 10.0 2.8 41 5.1 2.8 2.2 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3040 PF11239.8 KFP05427.1 - 1.8 8.9 3.9 23 5.3 3.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) PI3K_1B_p101 PF10486.9 KFP05428.1 - 2.4e-64 217.6 0.8 2.6e-64 217.4 0.8 1.0 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Laminin_N PF00055.17 KFP05429.1 - 9.2e-45 153.0 0.1 9.2e-45 153.0 0.1 2.9 2 1 2 4 4 4 1 Laminin N-terminal (Domain VI) NTR PF01759.21 KFP05429.1 - 1.7e-31 108.2 1.2 3.3e-31 107.3 1.2 1.5 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Laminin_EGF PF00053.24 KFP05429.1 - 2.3e-10 40.5 14.6 2.3e-10 40.5 14.6 3.4 3 0 0 3 3 3 2 Laminin EGF domain Baculo_PEP_C PF04513.12 KFP05430.1 - 0.0084 16.2 5.0 0.068 13.2 0.2 2.4 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus SNARE PF05739.19 KFP05430.1 - 0.085 12.9 0.2 0.19 11.7 0.2 1.6 1 0 0 1 1 1 0 SNARE domain ApoLp-III PF07464.11 KFP05430.1 - 0.31 11.1 5.6 0.41 10.7 0.3 2.6 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF1664 PF07889.12 KFP05430.1 - 6 6.9 6.7 4.7 7.3 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF745 PF05335.13 KFP05430.1 - 8.5 6.1 7.3 6.9 6.4 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) TLD PF07534.16 KFP05431.1 - 1.9e-28 99.5 0.0 8.8e-15 55.1 0.0 2.4 2 0 0 2 2 2 2 TLD RabGAP-TBC PF00566.18 KFP05431.1 - 3.5e-24 85.7 0.1 6.3e-24 84.8 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain WD40 PF00400.32 KFP05432.1 - 4.3e-35 119.1 23.4 0.00013 22.7 0.3 11.4 11 1 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP05432.1 - 5.7e-09 36.2 4.1 2.9 8.2 0.1 7.8 2 2 8 11 11 11 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFP05432.1 - 1.3e-06 28.0 2.5 0.0077 15.6 0.1 3.9 3 1 1 4 4 4 3 WD40-like domain Lgl_C PF08596.10 KFP05432.1 - 0.00096 18.0 0.1 0.0048 15.6 0.0 2.0 1 1 1 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal BBS2_Mid PF14783.6 KFP05432.1 - 0.0011 19.0 0.6 0.37 10.8 0.0 4.2 2 1 3 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.11 KFP05432.1 - 0.0065 15.3 4.7 5.5 5.6 0.2 4.7 2 1 2 4 4 4 2 Nup133 N terminal like UCH PF00443.29 KFP05433.1 - 4.6e-05 23.0 0.0 6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase BAR PF03114.18 KFP05434.1 - 2e-57 194.6 4.7 4.1e-57 193.6 4.7 1.5 1 0 0 1 1 1 1 BAR domain RhoGAP PF00620.27 KFP05434.1 - 6.5e-46 155.9 0.1 4.2e-45 153.3 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain Atg14 PF10186.9 KFP05434.1 - 4 6.4 6.1 0.43 9.6 0.8 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 p450 PF00067.22 KFP05435.1 - 8.6e-130 433.6 0.1 9.7e-130 433.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF846 PF05832.12 KFP05436.1 - 1.3e-54 184.0 8.3 1.6e-54 183.8 8.3 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF2079 PF09852.9 KFP05436.1 - 0.055 12.3 2.0 0.31 9.8 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2079) TMEM192 PF14802.6 KFP05436.1 - 0.22 10.6 1.8 0.35 9.9 1.8 1.3 1 0 0 1 1 1 0 TMEM192 family PMP22_Claudin PF00822.20 KFP05437.1 - 1.3e-31 109.7 7.9 1.4e-31 109.6 7.9 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP05437.1 - 4.4e-08 33.1 10.6 5.1e-08 32.9 10.6 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF2723 PF11028.8 KFP05437.1 - 0.0028 17.6 4.0 0.0034 17.3 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2723) SUR7 PF06687.12 KFP05437.1 - 0.04 13.6 10.0 0.05 13.2 10.0 1.1 1 0 0 1 1 1 0 SUR7/PalI family Amastin PF07344.11 KFP05437.1 - 0.042 13.7 6.4 0.048 13.5 6.4 1.1 1 0 0 1 1 1 0 Amastin surface glycoprotein Sugar_tr PF00083.24 KFP05437.1 - 0.084 11.7 6.7 0.095 11.5 6.7 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter DUF1980 PF09323.10 KFP05437.1 - 0.096 12.6 0.1 0.15 11.9 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) L_HMGIC_fpl PF10242.9 KFP05437.1 - 0.1 12.8 7.6 0.051 13.8 5.9 1.4 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein Clc-like PF07062.12 KFP05437.1 - 0.23 10.9 10.1 0.43 10.0 10.1 1.6 1 1 0 1 1 1 0 Clc-like 7TMR-DISM_7TM PF07695.11 KFP05437.1 - 0.5 10.2 14.0 0.79 9.6 12.3 1.7 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF4064 PF13273.6 KFP05437.1 - 6 7.2 12.0 0.53 10.6 4.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Comm PF15957.5 KFP05437.1 - 9 6.7 5.7 12 6.3 5.7 1.5 1 1 0 1 1 1 0 Commissureless Sulfotransfer_1 PF00685.27 KFP05438.1 - 3.3e-31 108.8 0.0 3.9e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP05438.1 - 3.7e-11 43.8 0.0 5.6e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFP05438.1 - 0.0069 16.3 0.0 0.063 13.2 0.0 2.0 2 0 0 2 2 2 1 Sulfotransferase family UbiA PF01040.18 KFP05439.1 - 2.2e-57 194.3 14.8 3.1e-57 193.7 14.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Sulfotransfer_1 PF00685.27 KFP05440.1 - 3.3e-31 108.8 0.0 3.9e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP05440.1 - 3.7e-11 43.8 0.0 5.6e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFP05440.1 - 0.0069 16.3 0.0 0.063 13.2 0.0 2.0 2 0 0 2 2 2 1 Sulfotransferase family NTR PF01759.21 KFP05441.1 - 0.011 15.6 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 UNC-6/NTR/C345C module TIMP PF00965.17 KFP05441.1 - 0.05 13.4 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 Tissue inhibitor of metalloproteinase WSD PF15613.6 KFP05441.1 - 0.19 12.2 0.0 0.36 11.3 0.0 1.4 1 0 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Glycos_transf_2 PF00535.26 KFP05442.1 - 1.4e-17 64.0 0.0 3e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KFP05442.1 - 7.9e-06 25.9 0.0 9.9e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KFP05442.1 - 0.00063 20.2 0.0 0.0076 16.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 TFCD_C PF12612.8 KFP05443.1 - 1.7e-70 236.7 0.5 3.8e-69 232.3 0.0 3.2 4 0 0 4 4 4 1 Tubulin folding cofactor D C terminal HEAT_EZ PF13513.6 KFP05443.1 - 3.6e-06 27.4 12.2 0.34 11.5 0.0 7.6 9 1 0 9 9 9 2 HEAT-like repeat HEAT PF02985.22 KFP05443.1 - 2.3e-05 24.3 10.0 0.17 12.2 0.0 8.3 9 0 0 9 9 9 1 HEAT repeat HEAT_2 PF13646.6 KFP05443.1 - 0.00072 19.9 2.8 0.84 10.1 0.0 4.6 5 0 0 5 5 5 2 HEAT repeats Cnd1 PF12717.7 KFP05443.1 - 0.0019 18.3 0.0 1.7 8.7 0.0 4.7 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 STAG PF08514.11 KFP05443.1 - 0.073 13.0 0.5 15 5.6 0.0 3.2 2 0 0 2 2 2 0 STAG domain HEAT_PBS PF03130.16 KFP05443.1 - 0.28 12.0 4.6 31 5.6 0.0 5.7 8 0 0 8 8 8 0 PBS lyase HEAT-like repeat zf-C2H2_7 PF15269.6 KFP05444.1 - 1.8e-36 123.9 11.3 5.9e-36 122.3 11.3 1.9 1 0 0 1 1 1 1 Zinc-finger zf-H2C2_5 PF13909.6 KFP05444.1 - 0.15 11.9 5.5 0.34 10.7 5.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFP05444.1 - 3.2 8.4 11.3 1.2 9.7 5.9 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type Fructosamin_kin PF03881.14 KFP05445.1 - 1.4e-74 250.9 0.0 3.6e-74 249.6 0.0 1.6 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KFP05445.1 - 2.1e-14 54.0 0.0 3e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFP05445.1 - 0.0015 18.2 0.0 0.031 13.9 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Pkinase_Tyr PF07714.17 KFP05445.1 - 0.0067 15.7 0.0 0.0087 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Fructosamin_kin PF03881.14 KFP05446.1 - 1.6e-69 234.3 0.4 5.7e-69 232.5 0.4 1.7 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KFP05446.1 - 2.8e-08 34.0 0.0 3.6e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4763 PF15960.5 KFP05446.1 - 0.025 13.9 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) PI3K_P85_iSH2 PF16454.5 KFP05446.1 - 0.044 13.4 0.2 0.064 12.8 0.2 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain RIO1 PF01163.22 KFP05446.1 - 0.13 11.8 0.0 5.4 6.6 0.0 2.2 2 0 0 2 2 2 0 RIO1 family ANAPC4_WD40 PF12894.7 KFP05447.1 - 1.6e-05 25.1 0.0 0.22 11.8 0.0 3.7 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 KFP05447.1 - 0.089 11.9 0.0 0.19 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) PHTB1_N PF14727.6 KFP05447.1 - 0.095 12.0 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 PTHB1 N-terminus WD40 PF00400.32 KFP05447.1 - 0.18 12.8 7.4 0.78 10.7 0.2 4.2 4 2 1 5 5 5 0 WD domain, G-beta repeat Forkhead PF00250.18 KFP05448.1 - 5.3e-41 138.8 0.2 8.9e-41 138.1 0.2 1.4 1 0 0 1 1 1 1 Forkhead domain Fe_hyd_lg_C PF02906.14 KFP05449.1 - 1.7e-70 237.4 0.1 2.9e-70 236.7 0.1 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 KFP05449.1 - 4.5e-09 36.3 1.1 5.6e-09 35.9 0.1 1.8 2 0 0 2 2 2 1 Iron hydrogenase small subunit DUF4564 PF15169.6 KFP05450.1 - 8.8e-80 266.8 0.0 9.7e-80 266.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4564) UbiA PF01040.18 KFP05450.1 - 0.049 12.9 0.6 0.059 12.7 0.1 1.3 2 0 0 2 2 2 0 UbiA prenyltransferase family Glyco_hydro_20 PF00728.22 KFP05451.1 - 1.9e-09 37.4 1.0 3.8e-09 36.4 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain DUF3546 PF12066.8 KFP05451.1 - 0.99 9.6 2.8 0.71 10.1 0.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3546) 2OG-FeII_Oxy_3 PF13640.6 KFP05452.1 - 9.7e-11 42.4 0.1 1.7e-10 41.6 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Oxygenase-NA PF09859.9 KFP05452.1 - 0.042 13.4 0.3 0.36 10.3 0.3 2.3 1 1 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA 7tm_1 PF00001.21 KFP05453.1 - 3.6e-21 75.7 4.5 4.2e-21 75.5 4.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFP05453.1 - 0.0003 20.2 0.9 0.0004 19.8 0.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw O-ag_pol_Wzy PF14296.6 KFP05453.1 - 0.0036 16.0 3.4 0.0051 15.5 2.9 1.5 1 1 1 2 2 2 1 O-antigen polysaccharide polymerase Wzy DUF443 PF04276.12 KFP05453.1 - 0.023 14.5 0.7 0.039 13.7 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF443) Anticodon_1 PF08264.13 KFP05453.1 - 0.033 14.1 0.3 0.073 13.0 0.2 1.6 1 1 0 1 1 1 0 Anticodon-binding domain of tRNA FA_desaturase PF00487.24 KFP05453.1 - 0.085 12.7 1.1 0.11 12.3 0.7 1.3 1 1 0 1 1 1 0 Fatty acid desaturase Defensin_beta PF00711.19 KFP05454.1 - 2.2e-08 34.0 11.2 2.7e-08 33.7 11.2 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_propep PF00879.18 KFP05454.1 - 0.00014 22.1 3.8 0.00016 21.9 3.8 1.1 1 0 0 1 1 1 1 Defensin propeptide Defensin_big PF14862.6 KFP05454.1 - 0.81 10.0 5.2 1.3 9.4 5.2 1.6 1 1 0 1 1 1 0 Big defensin TRAM_LAG1_CLN8 PF03798.16 KFP05456.1 - 1.1e-22 80.8 16.6 1.1e-22 80.8 16.6 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KFP05456.1 - 7.9e-20 70.3 0.4 7.9e-20 70.3 0.4 2.3 2 0 0 2 2 2 1 TRAM1-like protein RhodobacterPufX PF11511.8 KFP05456.1 - 0.039 13.5 0.0 0.15 11.7 0.0 2.0 1 0 0 1 1 1 0 Intrinsic membrane protein PufX DUF2207 PF09972.9 KFP05456.1 - 0.95 8.1 5.4 0.31 9.8 2.7 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4834 PF16118.5 KFP05456.1 - 1.6 9.7 9.4 5.1 8.1 0.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF1126 PF06565.12 KFP05457.1 - 8.6e-103 337.3 2.9 1.1e-34 118.4 0.2 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_6 PF13405.6 KFP05457.1 - 0.085 12.8 0.1 0.36 10.9 0.1 2.2 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 KFP05457.1 - 0.094 12.3 0.2 0.35 10.5 0.2 2.1 1 0 0 1 1 1 0 EF hand HlyIII PF03006.20 KFP05458.1 - 1.3e-50 172.2 17.5 1.3e-50 172.2 17.5 1.4 2 0 0 2 2 2 1 Haemolysin-III related DUF5504 PF17608.2 KFP05458.1 - 0.013 15.6 4.5 0.013 15.6 4.5 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5504) MCM PF00493.23 KFP05459.1 - 5.6e-97 323.2 0.0 8.9e-97 322.6 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFP05459.1 - 7.9e-35 119.5 1.2 9.4e-35 119.2 0.2 1.6 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 KFP05459.1 - 2.1e-21 76.1 3.2 5.3e-21 74.8 3.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFP05459.1 - 2.3e-08 34.6 1.0 5.5e-08 33.3 0.0 2.2 2 0 0 2 2 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFP05459.1 - 1.2e-07 31.4 0.0 7.5e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KFP05459.1 - 0.0029 17.5 0.0 0.0096 15.8 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFP05459.1 - 0.012 15.7 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KFP05459.1 - 0.059 13.1 0.0 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain CPSF100_C PF13299.6 KFP05459.1 - 0.09 13.0 4.7 0.19 11.9 4.7 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FAM176 PF14851.6 KFP05459.1 - 0.66 9.6 5.2 0.66 9.6 3.5 1.9 2 0 0 2 2 2 0 FAM176 family Gar1 PF04410.14 KFP05459.1 - 1.6 8.5 5.2 3.6 7.3 5.2 1.6 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region IL17 PF06083.11 KFP05460.1 - 3.1e-29 101.3 0.1 4.5e-29 100.8 0.1 1.3 1 0 0 1 1 1 1 Interleukin-17 IL17 PF06083.11 KFP05461.1 - 1.4e-31 108.7 0.8 2e-31 108.3 0.2 1.5 2 0 0 2 2 2 1 Interleukin-17 TF_AP-2 PF03299.14 KFP05462.1 - 1.9e-87 292.3 0.0 2.6e-87 291.9 0.0 1.2 1 0 0 1 1 1 1 Transcription factor AP-2 TF_AP-2 PF03299.14 KFP05463.1 - 4.3e-85 284.7 0.0 7.5e-85 283.9 0.0 1.4 1 0 0 1 1 1 1 Transcription factor AP-2 CAP PF00188.26 KFP05464.1 - 1.2e-24 87.5 8.9 1.5e-24 87.3 8.9 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Crisp PF08562.10 KFP05464.1 - 1.1 10.0 8.8 0.33 11.6 5.3 2.1 2 0 0 2 2 2 0 Crisp Crisp PF08562.10 KFP05465.1 - 1.5e-21 76.7 15.0 4e-21 75.3 15.0 1.8 1 0 0 1 1 1 1 Crisp CAP PF00188.26 KFP05465.1 - 2.6e-21 76.8 4.5 4e-21 76.1 4.5 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ShK PF01549.24 KFP05465.1 - 0.061 13.9 7.1 0.061 13.9 7.1 3.5 3 1 1 4 4 4 0 ShK domain-like Ammonium_transp PF00909.21 KFP05466.1 - 1.5e-74 251.1 25.4 1.7e-74 250.9 25.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family GWT1 PF06423.12 KFP05466.1 - 0.02 15.0 1.2 0.05 13.7 1.2 1.6 1 0 0 1 1 1 0 GWT1 Corona_M PF01635.18 KFP05466.1 - 0.79 9.0 5.5 0.54 9.5 2.6 2.0 1 1 1 2 2 2 0 Coronavirus M matrix/glycoprotein p450 PF00067.22 KFP05467.1 - 9.1e-118 393.9 1.3 3.7e-117 391.9 0.0 1.9 1 1 1 2 2 2 2 Cytochrome P450 CENP-Q PF13094.6 KFP05468.1 - 4e-14 53.2 14.9 6e-14 52.6 14.9 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit MAD PF05557.13 KFP05468.1 - 0.00058 18.4 13.1 0.00062 18.3 13.1 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein ATG16 PF08614.11 KFP05468.1 - 0.0025 18.1 9.0 0.0025 18.1 9.0 1.4 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) Interfer-bind PF09294.10 KFP05468.1 - 0.092 13.1 0.7 0.34 11.3 0.1 2.0 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III DUF4449 PF14613.6 KFP05468.1 - 0.093 12.8 2.6 0.15 12.2 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) Nsp1_C PF05064.13 KFP05468.1 - 0.77 9.6 12.8 1.8 8.4 6.6 2.4 2 0 0 2 2 2 0 Nsp1-like C-terminal region MatP_C PF17414.2 KFP05468.1 - 2.1 8.6 7.0 0.43 10.8 0.4 2.8 2 1 0 2 2 2 0 MatP C-terminal ribbon-helix-helix domain Hrs_helical PF12210.8 KFP05468.1 - 2.4 8.7 9.7 5 7.7 0.9 3.2 1 1 1 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Syntaxin-6_N PF09177.11 KFP05468.1 - 8.4 7.0 9.9 6.2 7.4 4.2 3.0 2 1 1 3 3 3 0 Syntaxin 6, N-terminal MM_CoA_mutase PF01642.22 KFP05469.1 - 4.1e-235 781.2 0.0 4.8e-235 780.9 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 KFP05469.1 - 8e-14 51.7 0.1 2e-13 50.4 0.1 1.7 1 0 0 1 1 1 1 B12 binding domain PMBR PF09373.10 KFP05469.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Pseudomurein-binding repeat 7tm_1 PF00001.21 KFP05470.1 - 5.1e-35 121.1 13.4 6.3e-35 120.8 13.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFP05470.1 - 7.5e-06 25.5 13.2 1.4e-05 24.6 13.2 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Bac_rhodopsin PF01036.18 KFP05470.1 - 0.16 11.5 9.6 0.045 13.3 5.1 2.1 2 1 0 2 2 2 0 Bacteriorhodopsin-like protein 7tm_4 PF13853.6 KFP05470.1 - 0.18 11.5 7.1 0.46 10.2 7.1 1.9 1 1 0 1 1 1 0 Olfactory receptor DHHC PF01529.20 KFP05470.1 - 6.9 6.8 12.5 6.1 7.0 3.8 2.4 2 1 0 2 2 2 0 DHHC palmitoyltransferase zf-H2C2_2 PF13465.6 KFP05472.1 - 1.4e-27 94.9 86.1 2e-07 31.1 4.4 10.2 9 2 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFP05472.1 - 2.8e-18 65.3 77.2 0.002 18.4 9.0 8.5 9 0 0 9 9 8 7 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFP05472.1 - 9.4e-16 57.3 12.9 5.9e-08 32.3 0.2 9.2 8 2 0 8 8 8 4 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KFP05472.1 - 1.6e-12 47.1 74.9 0.01 16.6 0.2 8.8 9 0 0 9 9 8 6 C2H2-type zinc finger zf-C2H2_7 PF15269.6 KFP05472.1 - 0.0058 16.7 2.4 0.0058 16.7 2.4 6.6 3 3 4 7 7 6 3 Zinc-finger BolA PF01722.18 KFP05472.1 - 0.02 15.2 7.5 0.98 9.7 0.6 3.2 3 0 0 3 3 3 0 BolA-like protein C1_2 PF03107.16 KFP05472.1 - 0.025 14.9 33.6 12 6.4 0.9 7.9 8 0 0 8 8 8 0 C1 domain DUF678 PF05077.12 KFP05472.1 - 0.033 14.3 0.5 1.6 8.9 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF678) DUF1764 PF08576.10 KFP05472.1 - 0.072 14.0 2.6 0.61 11.0 0.2 2.4 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DUF2225 PF09986.9 KFP05472.1 - 0.078 12.7 0.4 0.078 12.7 0.4 3.8 4 1 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) GAGA PF09237.11 KFP05472.1 - 0.14 12.0 12.6 0.28 11.0 0.3 3.9 4 0 0 4 4 4 0 GAGA factor zinc_ribbon_15 PF17032.5 KFP05472.1 - 5.5 7.8 22.6 2.4 9.0 3.6 4.4 1 1 4 5 5 5 0 zinc-ribbon family zf-C2H2_jaz PF12171.8 KFP05472.1 - 9.7 6.6 0.0 0.35 11.2 1.8 7.6 8 1 0 8 8 7 0 Zinc-finger double-stranded RNA-binding Myb_Cef PF11831.8 KFP05473.1 - 1.6e-87 293.0 5.3 1.6e-87 293.0 5.3 3.8 5 0 0 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KFP05473.1 - 3.3e-20 72.0 6.5 1.3e-11 44.5 1.9 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFP05473.1 - 1.6e-18 66.7 9.0 1.9e-13 50.4 4.5 3.1 2 1 1 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.8 KFP05473.1 - 0.033 14.3 0.6 0.2 11.7 0.2 2.6 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Pox_A_type_inc PF04508.12 KFP05473.1 - 4.7 7.2 8.4 1.4 8.9 2.2 3.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat TFIID-18kDa PF02269.16 KFP05475.1 - 1.5e-29 101.8 0.1 5.4e-29 100.1 0.3 1.9 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit GST_C_2 PF13410.6 KFP05476.1 - 9.2e-09 35.2 0.0 2.4e-08 33.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFP05476.1 - 2.7e-06 27.7 0.0 4.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFP05476.1 - 9.9e-06 25.8 0.0 1.7e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFP05476.1 - 0.00034 20.8 0.6 0.0019 18.4 0.2 2.5 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFP05476.1 - 0.021 15.0 0.7 0.052 13.7 0.2 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Phosphodiest PF01663.22 KFP05478.1 - 3e-84 283.7 1.6 3.5e-84 283.4 1.6 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KFP05478.1 - 7.9e-07 28.8 0.0 0.00024 20.6 0.0 2.4 3 0 0 3 3 3 2 Sulfatase Metalloenzyme PF01676.18 KFP05478.1 - 0.00046 19.6 0.0 0.00072 19.0 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF1501 PF07394.12 KFP05478.1 - 0.035 13.2 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Phosphodiest PF01663.22 KFP05479.1 - 1.2e-84 284.9 1.7 1.4e-84 284.7 1.7 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KFP05479.1 - 1.4e-06 28.0 0.0 0.022 14.1 0.0 2.4 2 1 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 KFP05479.1 - 0.055 12.8 0.0 0.11 11.9 0.0 1.6 1 1 0 1 1 1 0 Metalloenzyme superfamily Calcipressin PF04847.12 KFP05480.1 - 4.2e-64 215.7 0.3 5.3e-64 215.4 0.3 1.1 1 0 0 1 1 1 1 Calcipressin RRM_1 PF00076.22 KFP05480.1 - 0.013 15.3 0.3 0.023 14.5 0.3 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP05480.1 - 0.035 13.9 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif p450 PF00067.22 KFP05481.1 - 1.2e-58 199.0 0.2 1.7e-58 198.5 0.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 Utp13 PF08625.11 KFP05481.1 - 0.13 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Mito_carr PF00153.27 KFP05482.1 - 2.1e-67 223.1 0.8 7.4e-21 73.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein TUDOR PF00567.24 KFP05483.1 - 2.5e-153 502.1 8.3 2.5e-31 108.2 0.3 7.7 7 0 0 7 7 7 7 Tudor domain SMN PF06003.12 KFP05483.1 - 7.2e-13 48.4 0.1 0.0031 16.8 0.0 4.5 4 0 0 4 4 4 4 Survival motor neuron protein (SMN) DUF4537 PF15057.6 KFP05483.1 - 2.6e-11 43.6 0.2 0.43 10.6 0.0 6.4 6 0 0 6 6 6 3 Domain of unknown function (DUF4537) Agenet PF05641.12 KFP05483.1 - 2.9e-10 40.5 5.1 0.12 12.9 0.0 7.3 7 0 0 7 7 7 2 Agenet domain DUF1325 PF07039.11 KFP05483.1 - 5.2e-06 26.6 0.0 0.62 10.1 0.0 3.9 4 0 0 4 4 4 2 SGF29 tudor-like domain Tudor_2 PF18104.1 KFP05483.1 - 0.057 13.1 3.9 4 7.2 0.0 3.7 3 0 0 3 3 3 0 Jumonji domain-containing protein 2A Tudor domain Spore_coat_CotO PF14153.6 KFP05483.1 - 0.068 13.1 0.3 10 6.0 0.0 3.5 4 0 0 4 4 4 0 Spore coat protein CotO Tudor_FRX1 PF18336.1 KFP05483.1 - 0.14 12.1 0.0 7 6.6 0.0 3.1 3 0 0 3 3 3 0 Fragile X mental retardation Tudor domain PAF-AH_p_II PF03403.13 KFP05485.1 - 1.6e-172 573.2 0.0 2e-172 572.9 0.0 1.0 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KFP05485.1 - 1.1e-09 37.5 0.0 1e-08 34.4 0.0 2.0 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KFP05485.1 - 9.5e-06 24.8 0.0 0.03 13.4 0.0 2.3 2 0 0 2 2 2 2 Chlorophyllase Hydrolase_4 PF12146.8 KFP05485.1 - 2.8e-05 23.5 0.0 0.086 12.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFP05485.1 - 5.5e-05 22.7 0.0 0.00017 21.1 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 KFP05485.1 - 0.0014 18.5 0.0 0.0049 16.6 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 KFP05485.1 - 0.0028 17.2 0.0 0.0061 16.1 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 KFP05485.1 - 0.017 14.8 0.0 0.088 12.4 0.0 2.0 2 0 0 2 2 2 0 Putative esterase AXE1 PF05448.12 KFP05485.1 - 0.019 13.6 0.0 0.69 8.5 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 KFP05485.1 - 0.036 13.9 0.1 1.3 8.7 0.0 2.4 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KFP05485.1 - 0.042 13.7 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFP05485.1 - 0.11 13.1 0.0 0.19 12.3 0.0 1.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family Fungal_lectin_2 PF18647.1 KFP05485.1 - 0.11 13.0 0.2 1.1 9.8 0.1 2.1 2 0 0 2 2 2 0 Alpha-galactosyl-binding fungal lectin Lipase_3 PF01764.25 KFP05485.1 - 0.16 11.9 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) S4 PF01479.25 KFP05486.1 - 2e-07 30.6 0.0 5.5e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 KFP05486.1 - 0.0011 19.8 2.4 0.003 18.4 2.4 1.8 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Ank_2 PF12796.7 KFP05487.1 - 7.1e-17 61.8 0.0 4.7e-15 56.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP05487.1 - 5.7e-15 55.5 1.0 3.3e-09 37.1 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP05487.1 - 6e-13 47.7 0.4 0.00086 19.6 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KFP05487.1 - 4.3e-12 46.0 1.4 6.6e-05 23.1 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFP05487.1 - 3.8e-08 33.4 3.4 7.3e-05 23.0 0.2 3.5 3 1 0 3 3 3 2 Ankyrin repeat TAS2R PF05296.13 KFP05488.1 - 1.9e-58 198.0 37.9 2.1e-58 197.8 37.9 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) TAS2R PF05296.13 KFP05489.1 - 3.4e-57 193.9 33.3 4e-57 193.6 33.3 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) Myosin_head PF00063.21 KFP05490.1 - 2.8e-264 878.5 10.1 3.4e-264 878.2 10.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 KFP05490.1 - 8.5e-06 25.1 6.3 0.0016 18.0 1.8 2.6 2 0 0 2 2 2 2 IQ calmodulin-binding motif Myosin_N PF02736.19 KFP05490.1 - 0.00086 19.1 1.5 0.0013 18.5 0.4 1.9 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 KFP05490.1 - 0.0037 17.6 0.0 0.018 15.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFP05490.1 - 0.02 15.3 0.0 0.064 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 KFP05490.1 - 0.077 12.3 0.1 1 8.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin T2SSE PF00437.20 KFP05490.1 - 0.12 11.5 0.0 0.29 10.2 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 KFP05490.1 - 0.12 12.0 0.1 0.52 10.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain LMBR1 PF04791.16 KFP05491.1 - 0.0038 16.2 8.1 0.004 16.1 8.1 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein bZIP_1 PF00170.21 KFP05491.1 - 0.0061 16.6 17.3 0.038 14.1 7.0 2.4 2 0 0 2 2 2 1 bZIP transcription factor DUF2508 PF10704.9 KFP05491.1 - 0.0099 16.0 2.8 0.0099 16.0 2.8 2.4 1 1 0 2 2 2 1 Protein of unknown function (DUF2508) FapA PF03961.13 KFP05491.1 - 0.014 14.0 10.5 0.016 13.9 10.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Taxilin PF09728.9 KFP05491.1 - 0.016 14.4 7.0 0.016 14.4 7.0 2.4 2 1 1 3 3 3 0 Myosin-like coiled-coil protein Csm1_N PF18504.1 KFP05491.1 - 0.02 15.2 19.1 0.13 12.7 2.8 2.5 3 0 0 3 3 2 0 Csm1 N-terminal domain dCache_1 PF02743.18 KFP05491.1 - 0.034 13.9 0.7 0.042 13.6 0.7 1.3 1 0 0 1 1 1 0 Cache domain DUF2492 PF10678.9 KFP05491.1 - 0.058 13.7 1.0 0.12 12.6 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2492) DUF4407 PF14362.6 KFP05491.1 - 0.093 12.1 7.1 0.13 11.6 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1825 PF08855.10 KFP05491.1 - 0.11 12.5 7.9 0.044 13.7 4.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1825) DUF2408 PF10303.9 KFP05491.1 - 0.11 13.1 9.5 0.13 12.9 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) TMF_DNA_bd PF12329.8 KFP05491.1 - 0.14 12.2 16.6 0.36 10.9 3.7 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ApoO PF09769.9 KFP05491.1 - 0.14 12.1 2.8 2.6 8.0 0.3 2.2 2 0 0 2 2 2 0 Apolipoprotein O GAS PF13851.6 KFP05491.1 - 0.14 11.4 24.9 0.99 8.7 24.9 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Baculo_p24 PF05073.12 KFP05491.1 - 0.17 11.6 3.5 0.22 11.3 3.5 1.2 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Seryl_tRNA_N PF02403.22 KFP05491.1 - 0.19 12.0 14.0 2.9 8.2 14.0 2.2 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain RasGAP_C PF03836.15 KFP05491.1 - 0.23 11.6 14.1 0.32 11.2 4.3 2.1 1 1 1 2 2 2 0 RasGAP C-terminus Prefoldin PF02996.17 KFP05491.1 - 0.31 11.0 16.6 0.65 9.9 4.6 2.4 3 0 0 3 3 2 0 Prefoldin subunit ECH_2 PF16113.5 KFP05491.1 - 0.31 10.5 3.8 0.32 10.4 3.8 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase IZUMO PF15005.6 KFP05491.1 - 0.36 11.3 14.8 0.23 12.0 12.0 1.8 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated KxDL PF10241.9 KFP05491.1 - 0.45 10.8 14.7 0.39 11.0 3.9 2.4 1 1 0 2 2 2 0 Uncharacterized conserved protein betaPIX_CC PF16523.5 KFP05491.1 - 0.48 10.3 14.1 3.9 7.4 9.2 2.5 1 1 1 2 2 2 0 betaPIX coiled coil DHHA1 PF02272.19 KFP05491.1 - 0.62 10.5 7.7 1.1 9.7 0.8 2.1 2 0 0 2 2 2 0 DHHA1 domain DUF812 PF05667.11 KFP05491.1 - 0.82 8.5 19.5 1 8.2 19.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TMF_TATA_bd PF12325.8 KFP05491.1 - 0.92 9.8 20.8 2 8.7 7.7 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 KFP05491.1 - 1 9.9 28.7 0.4 11.2 11.1 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region NPV_P10 PF05531.12 KFP05491.1 - 1.2 9.6 10.1 3.8 8.0 1.4 2.5 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 KFP05491.1 - 1.3 9.1 7.0 9.6 6.2 5.9 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 KFP05491.1 - 1.3 6.9 7.6 1.6 6.6 7.6 1.2 1 0 0 1 1 1 0 Prominin OmpH PF03938.14 KFP05491.1 - 1.6 9.0 25.7 8.5 6.7 21.0 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Uso1_p115_C PF04871.13 KFP05491.1 - 1.8 8.9 18.8 1.3 9.4 16.3 1.9 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region RNase_E_G PF10150.9 KFP05491.1 - 1.8 7.9 10.2 9.6 5.5 10.2 1.8 1 1 0 1 1 1 0 Ribonuclease E/G family ALMT PF11744.8 KFP05491.1 - 1.9 7.3 7.8 2.1 7.1 7.8 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF724 PF05266.14 KFP05491.1 - 2.4 7.9 15.0 2.6 7.8 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Sulfatase_C PF14707.6 KFP05491.1 - 2.6 8.8 5.1 14 6.4 0.9 2.2 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase TMPIT PF07851.13 KFP05491.1 - 2.9 7.1 15.4 0.7 9.1 5.0 2.0 1 1 1 2 2 2 0 TMPIT-like protein Vir_act_alpha_C PF10400.9 KFP05491.1 - 3.2 8.5 18.6 5.4 7.8 8.3 2.6 1 1 1 2 2 2 0 Virulence activator alpha C-term DUF4795 PF16043.5 KFP05491.1 - 3.2 7.3 18.4 15 5.1 16.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Spc7 PF08317.11 KFP05491.1 - 3.9 6.3 20.9 12 4.7 20.9 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein SEO_N PF14576.6 KFP05491.1 - 4.4 6.4 9.2 0.63 9.2 2.0 2.1 1 1 1 2 2 2 0 Sieve element occlusion N-terminus Exonuc_VII_L PF02601.15 KFP05491.1 - 4.9 6.6 11.0 6.1 6.3 11.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-C4H2 PF10146.9 KFP05491.1 - 5.5 7.2 11.4 7.5 6.8 11.4 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein Phage_GP20 PF06810.11 KFP05491.1 - 5.5 6.8 18.8 0.9 9.3 3.0 2.4 2 1 1 3 3 2 0 Phage minor structural protein GP20 Prefoldin_2 PF01920.20 KFP05491.1 - 5.7 6.9 23.5 1.6 8.8 7.6 2.7 3 0 0 3 3 2 0 Prefoldin subunit V_ATPase_I PF01496.19 KFP05491.1 - 5.8 4.7 12.3 7 4.4 12.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.10 KFP05491.1 - 5.9 7.1 13.0 6.5 6.9 12.0 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family ABC_tran_Xtn PF12848.7 KFP05491.1 - 6.3 6.9 14.9 2 8.5 4.1 2.2 2 0 0 2 2 2 0 ABC transporter DUF3450 PF11932.8 KFP05491.1 - 6.4 6.0 19.6 1.8 7.8 4.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TPD52 PF04201.15 KFP05491.1 - 6.6 6.3 11.7 3.3 7.3 9.6 1.6 1 1 0 1 1 1 0 Tumour protein D52 family Peptidase_S46 PF10459.9 KFP05491.1 - 7 5.2 10.4 8.7 4.8 10.4 1.0 1 0 0 1 1 1 0 Peptidase S46 HU-CCDC81_bac_2 PF18175.1 KFP05491.1 - 7.4 6.5 8.9 14 5.7 2.5 2.5 1 1 1 2 2 2 0 CCDC81-like prokaryotic HU domain 2 DivIC PF04977.15 KFP05491.1 - 7.8 6.4 21.3 7.7 6.4 5.9 2.6 2 1 0 2 2 2 0 Septum formation initiator YajC PF02699.15 KFP05491.1 - 8.5 6.3 9.0 0.3 11.0 0.2 2.6 3 1 0 3 3 2 0 Preprotein translocase subunit XhlA PF10779.9 KFP05491.1 - 8.6 6.7 12.2 6.9 6.9 1.7 2.4 2 0 0 2 2 2 0 Haemolysin XhlA TEX13 PF15186.6 KFP05491.1 - 9.3 5.9 16.2 2.1 8.0 7.3 2.3 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family Spore_GerAC PF05504.11 KFP05491.1 - 9.9 6.4 14.3 0.21 11.8 3.7 2.0 1 1 1 2 2 2 0 Spore germination B3/ GerAC like, C-terminal IQ PF00612.27 KFP05492.1 - 0.00021 20.8 0.4 0.00044 19.8 0.4 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif WW PF00397.26 KFP05494.1 - 2.7e-10 40.2 0.1 3.9e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 WW domain Asp PF00026.23 KFP05495.1 - 4.4e-37 128.2 0.0 5.6e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KFP05495.1 - 1.8e-10 40.8 0.0 2.6e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal zf-RING_2 PF13639.6 KFP05496.1 - 8.9e-06 25.9 10.3 1.5e-05 25.2 10.3 1.4 1 0 0 1 1 1 1 Ring finger domain Zn_ribbon_17 PF17120.5 KFP05496.1 - 7.6e-05 22.3 7.2 0.00012 21.6 7.2 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KFP05496.1 - 0.0017 18.6 10.7 0.0036 17.6 10.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFP05496.1 - 0.028 14.3 11.2 0.055 13.4 11.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP05496.1 - 0.06 13.4 10.3 0.12 12.4 10.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFP05496.1 - 0.14 12.0 12.5 0.28 11.1 12.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KFP05496.1 - 0.15 12.2 9.3 0.28 11.3 9.3 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_5 PF14634.6 KFP05496.1 - 0.19 11.7 8.7 0.47 10.5 8.7 1.7 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING-like PF08746.11 KFP05496.1 - 0.23 11.8 6.3 0.42 11.0 6.3 1.4 1 0 0 1 1 1 0 RING-like domain zf-ANAPC11 PF12861.7 KFP05496.1 - 0.32 11.1 6.7 0.79 9.8 6.6 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KFP05496.1 - 0.72 9.8 9.9 1.4 8.9 9.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KFP05496.1 - 4.7 7.0 6.6 12 5.7 6.6 1.8 1 0 0 1 1 1 0 RING-like zinc finger Peptidase_S8 PF00082.22 KFP05497.1 - 4.7e-37 127.9 0.9 6.5e-37 127.4 0.9 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KFP05497.1 - 2.4e-27 94.8 0.0 5.4e-27 93.6 0.0 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain Peptidase_S8_N PF16361.5 KFP05497.1 - 0.00089 19.8 0.2 0.0016 18.9 0.2 1.4 1 0 0 1 1 1 1 N-terminal of Subtilase family S8_pro-domain PF16470.5 KFP05497.1 - 0.0012 19.5 1.1 0.0025 18.5 1.1 1.5 1 0 0 1 1 1 1 Peptidase S8 pro-domain CH PF00307.31 KFP05498.1 - 4.6e-17 62.2 0.0 7.2e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 KFP05498.1 - 2.4e-11 43.1 4.2 6.5e-11 41.7 2.8 2.1 2 0 0 2 2 2 1 Calponin family repeat SID-1_RNA_chan PF13965.6 KFP05499.1 - 6.2e-226 751.5 22.2 1.7e-88 297.6 9.6 3.0 3 0 0 3 3 3 3 dsRNA-gated channel SID-1 ResB PF05140.14 KFP05499.1 - 0.064 12.0 0.8 0.086 11.6 0.8 1.1 1 0 0 1 1 1 0 ResB-like family PROL5-SMR PF15621.6 KFP05499.1 - 0.075 13.6 0.1 0.075 13.6 0.1 2.2 3 0 0 3 3 3 0 Proline-rich submaxillary gland androgen-regulated family MARVEL PF01284.23 KFP05499.1 - 3.6 7.6 15.3 0.054 13.5 1.6 3.0 3 0 0 3 3 3 0 Membrane-associating domain Lipase_GDSL_2 PF13472.6 KFP05500.1 - 0.00061 20.2 0.0 0.14 12.6 0.0 2.3 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Pkinase PF00069.25 KFP05501.1 - 2.2e-67 227.2 0.0 4.9e-67 226.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP05501.1 - 1.9e-35 122.4 1.7 3.2e-35 121.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP05501.1 - 7.4e-06 25.5 0.0 1.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFP05501.1 - 0.0034 16.8 0.7 0.0094 15.3 0.7 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFP05501.1 - 0.064 12.2 0.1 0.064 12.2 0.1 1.9 2 0 0 2 2 2 0 Haspin like kinase domain Apolipoprotein PF01442.18 KFP05502.1 - 2.7e-49 167.6 17.0 3.4e-49 167.3 15.5 1.7 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 KFP05502.1 - 4.9e-09 36.6 13.0 0.0021 18.5 0.3 5.2 1 1 3 4 4 4 2 YtxH-like protein DUF883 PF05957.13 KFP05502.1 - 3.6e-07 30.7 10.4 0.099 13.3 1.2 5.0 1 1 4 5 5 5 1 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.11 KFP05502.1 - 9.9e-06 25.7 8.5 0.0036 17.4 0.3 3.2 1 1 0 2 2 2 2 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 KFP05502.1 - 3.1e-05 24.0 6.3 0.078 13.0 0.4 3.6 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 KFP05502.1 - 0.0002 21.5 2.5 0.61 10.4 0.1 4.1 1 1 2 3 3 3 1 Bacterial protein of unknown function (DUF948) ApoA-II PF04711.13 KFP05502.1 - 0.00083 19.5 9.1 1.4 9.1 0.1 4.5 2 1 1 3 3 3 1 Apolipoprotein A-II (ApoA-II) Exonuc_VII_L PF02601.15 KFP05502.1 - 0.0009 18.9 8.2 0.0024 17.5 8.0 1.7 1 1 0 1 1 1 1 Exonuclease VII, large subunit Prominin PF05478.11 KFP05502.1 - 0.0011 17.0 3.8 0.035 12.1 3.0 2.0 1 1 1 2 2 2 2 Prominin VirE PF05272.11 KFP05502.1 - 0.0017 18.1 2.0 0.0069 16.1 0.2 2.2 1 1 1 2 2 2 1 Virulence-associated protein E Bacillus_HBL PF05791.11 KFP05502.1 - 0.002 18.0 6.3 0.069 13.0 0.6 2.8 1 1 2 3 3 3 1 Bacillus haemolytic enterotoxin (HBL) KMP11 PF03037.16 KFP05502.1 - 0.0058 17.4 3.2 2.3 9.1 0.3 3.4 1 1 2 3 3 3 1 Kinetoplastid membrane protein 11 DUF1978 PF09321.10 KFP05502.1 - 0.0061 15.9 4.1 0.0061 15.9 4.1 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF1978) DUF2959 PF11172.8 KFP05502.1 - 0.0079 16.3 11.7 0.089 12.9 4.5 2.6 1 1 2 3 3 3 1 Protein of unknown function (DUF2959) PIN_8 PF18476.1 KFP05502.1 - 0.0089 15.9 7.0 0.096 12.5 1.6 2.2 1 1 1 2 2 2 1 PIN like domain ApoO PF09769.9 KFP05502.1 - 0.011 15.7 4.0 1.1 9.2 1.1 3.7 1 1 1 2 2 2 0 Apolipoprotein O QIL1 PF15884.5 KFP05502.1 - 0.011 16.3 4.6 19 6.0 0.0 4.5 1 1 4 5 5 5 0 MICOS complex subunit MIC13, QIL1 Atg14 PF10186.9 KFP05502.1 - 0.012 14.7 8.1 0.017 14.3 8.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4015 PF13200.6 KFP05502.1 - 0.015 14.4 0.3 0.44 9.5 0.1 2.3 2 0 0 2 2 2 0 Putative glycosyl hydrolase domain Erp_C PF06780.11 KFP05502.1 - 0.017 15.1 1.5 0.017 15.1 1.5 2.7 1 1 0 2 2 2 0 Erp protein C-terminus 4HB_MCP_1 PF12729.7 KFP05502.1 - 0.026 14.1 8.6 0.063 12.8 4.2 2.3 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction Gp58 PF07902.11 KFP05502.1 - 0.028 12.7 0.8 0.05 11.9 0.3 1.4 1 1 0 1 1 1 0 gp58-like protein Phasin PF05597.11 KFP05502.1 - 0.029 14.4 8.5 1.1 9.3 1.6 2.9 1 1 2 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Fib_alpha PF08702.10 KFP05502.1 - 0.032 14.4 6.3 0.13 12.5 1.6 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF668 PF05003.12 KFP05502.1 - 0.034 14.6 3.7 0.24 11.9 0.2 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF668) Atypical_Card PF18461.1 KFP05502.1 - 0.035 14.3 5.6 2.3 8.5 0.9 3.1 2 1 1 3 3 3 0 Atypical caspase recruitment domain DUF2884 PF11101.8 KFP05502.1 - 0.036 13.6 1.8 0.5 9.8 1.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) LMP PF04778.12 KFP05502.1 - 0.039 13.9 7.5 0.041 13.8 0.9 2.4 1 1 1 2 2 2 0 LMP repeated region DUF445 PF04286.12 KFP05502.1 - 0.042 13.7 8.8 0.13 12.0 3.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF445) RapH_N PF18801.1 KFP05502.1 - 0.043 13.9 4.7 5.4 7.2 0.2 3.3 3 0 0 3 3 3 0 response regulator aspartate phosphatase H, N terminal BshC PF10079.9 KFP05502.1 - 0.047 12.4 13.0 0.14 10.9 7.4 2.1 1 1 1 2 2 2 0 Bacillithiol biosynthesis BshC APP_E2 PF12925.7 KFP05502.1 - 0.059 13.1 7.7 0.35 10.6 0.1 2.6 1 1 1 2 2 2 0 E2 domain of amyloid precursor protein Raptor_N PF14538.6 KFP05502.1 - 0.098 12.6 1.0 18 5.3 0.1 2.8 2 2 1 3 3 3 0 Raptor N-terminal CASPase like domain DUF1640 PF07798.11 KFP05502.1 - 0.14 12.2 10.6 15 5.6 10.6 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) ALS2CR8 PF15299.6 KFP05502.1 - 0.16 11.8 2.0 2.5 7.9 2.0 2.1 1 1 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 OmpH PF03938.14 KFP05502.1 - 0.17 12.3 14.7 0.3 11.4 5.5 2.6 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) BAG6 PF12057.8 KFP05502.1 - 0.17 11.6 5.9 26 4.6 0.0 4.4 2 2 2 4 4 4 0 BCL2-associated athanogene 6 DLP_helical PF18709.1 KFP05502.1 - 0.17 11.0 7.8 0.24 10.6 3.5 2.7 1 1 1 2 2 2 0 Dynamin-like helical domain TetR_C_13 PF16925.5 KFP05502.1 - 0.2 11.6 1.7 33 4.5 0.0 3.4 2 1 1 4 4 3 0 Tetracyclin repressor-like, C-terminal domain Imm49 PF15575.6 KFP05502.1 - 0.2 11.4 4.6 0.4 10.4 1.7 2.3 1 1 1 2 2 2 0 Immunity protein 49 DUF1451 PF07295.11 KFP05502.1 - 0.2 11.7 10.4 0.058 13.4 3.0 2.7 1 1 2 3 3 3 0 Zinc-ribbon containing domain ApoB100_C PF12491.8 KFP05502.1 - 0.25 11.3 3.8 2.4 8.2 0.0 4.1 3 2 2 5 5 4 0 Apolipoprotein B100 C terminal DUF1690 PF07956.11 KFP05502.1 - 0.28 11.6 14.0 3.2 8.2 0.7 3.2 1 1 2 3 3 3 0 Protein of Unknown function (DUF1690) FUSC PF04632.12 KFP05502.1 - 0.3 9.6 6.3 0.67 8.4 0.3 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family Snapin_Pallidin PF14712.6 KFP05502.1 - 0.32 11.4 13.4 2.1 8.8 2.1 3.6 1 1 1 3 3 2 0 Snapin/Pallidin PGK PF00162.19 KFP05502.1 - 0.34 9.8 1.3 0.6 9.0 0.5 1.7 1 1 1 2 2 2 0 Phosphoglycerate kinase Stathmin PF00836.19 KFP05502.1 - 0.35 10.8 11.6 2.4 8.1 2.4 3.2 2 1 1 3 3 3 0 Stathmin family KapB PF08810.10 KFP05502.1 - 0.37 11.0 6.5 1.9 8.7 1.2 3.4 1 1 1 3 3 3 0 Kinase associated protein B Histidinol_dh PF00815.20 KFP05502.1 - 0.38 9.7 1.9 0.71 8.8 0.4 1.8 2 0 0 2 2 2 0 Histidinol dehydrogenase TetR_C_37 PF18665.1 KFP05502.1 - 0.42 11.2 4.7 6 7.5 0.2 3.6 2 2 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain NPV_P10 PF05531.12 KFP05502.1 - 0.47 10.9 8.1 1.8 9.0 2.0 3.8 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein LUC7 PF03194.15 KFP05502.1 - 0.54 9.9 5.3 1 9.0 5.3 1.5 1 1 0 1 1 1 0 LUC7 N_terminus TipAS PF07739.13 KFP05502.1 - 0.61 10.7 7.4 16 6.1 5.9 3.3 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain Cnn_1N PF07989.11 KFP05502.1 - 0.67 10.1 12.2 7.7 6.8 3.7 3.5 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 PP_kinase_N PF13089.6 KFP05502.1 - 0.68 10.3 7.3 17 5.8 0.1 3.3 2 2 1 3 3 3 0 Polyphosphate kinase N-terminal domain CHASE6_C PF17150.4 KFP05502.1 - 0.71 10.6 6.4 6 7.6 0.8 3.3 1 1 2 3 3 3 0 C-terminal domain of two-partite extracellular sensor domain DUF2605 PF10792.9 KFP05502.1 - 0.77 9.7 6.0 1.5 8.8 0.2 3.0 2 1 0 3 3 2 0 Protein of unknown function (DUF2605) Gp49 PF05973.14 KFP05502.1 - 0.81 9.9 4.2 17 5.6 0.2 3.1 1 1 2 3 3 3 0 Phage derived protein Gp49-like (DUF891) DctP PF03480.13 KFP05502.1 - 0.82 8.9 7.5 2.4 7.4 0.3 2.7 1 1 2 3 3 3 0 Bacterial extracellular solute-binding protein, family 7 FAM76 PF16046.5 KFP05502.1 - 0.93 8.8 11.8 2.7 7.3 3.4 2.1 2 0 0 2 2 2 0 FAM76 protein Muted PF14942.6 KFP05502.1 - 1.1 9.6 10.6 3.4 8.0 6.3 2.8 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein DUF3106 PF11304.8 KFP05502.1 - 1.1 9.8 9.6 0.29 11.6 4.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) kleA_kleC PF17383.2 KFP05502.1 - 1.3 9.4 8.0 4.3 7.7 1.1 3.4 2 1 1 3 3 3 0 Uncharacterized KorC regulated protein A 7TMR-HDED PF07697.11 KFP05502.1 - 1.6 8.8 11.5 4.7 7.3 11.5 1.9 1 1 0 1 1 1 0 7TM-HD extracellular DUF4735 PF15882.5 KFP05502.1 - 2.1 7.7 3.9 4.2 6.7 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4735) IZUMO PF15005.6 KFP05502.1 - 2.7 8.5 9.9 2.7 8.5 3.9 2.6 1 1 2 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated DUF2203 PF09969.9 KFP05502.1 - 4.9 7.9 8.8 2.9e+02 2.2 8.8 3.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Gon7 PF08738.10 KFP05502.1 - 5.2 7.2 8.8 4.7 7.3 0.4 3.3 1 1 3 4 4 4 0 Gon7 family YlqD PF11068.8 KFP05502.1 - 5.2 7.4 12.2 2 8.8 2.5 2.9 1 1 1 2 2 2 0 YlqD protein CRR7 PF12095.8 KFP05502.1 - 6.1 7.4 8.7 2.9 8.4 0.9 3.3 1 1 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 CENP-H PF05837.12 KFP05502.1 - 7.3 7.0 15.1 9.2 6.7 6.0 3.1 1 1 2 3 3 3 0 Centromere protein H (CENP-H) YojJ PF10372.9 KFP05502.1 - 8.2 6.6 11.8 9 6.5 0.1 4.7 3 1 2 6 6 4 0 Bacterial membrane-spanning protein N-terminus MerR-DNA-bind PF09278.11 KFP05502.1 - 8.2 7.0 15.2 19 5.9 3.0 4.5 2 1 3 5 5 5 0 MerR, DNA binding zf-ZPR1 PF03367.13 KFP05504.1 - 2.5e-99 329.7 0.1 9.9e-50 168.5 0.0 2.0 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zinc-ribbons_6 PF07191.12 KFP05504.1 - 0.053 13.5 0.3 0.053 13.5 0.3 2.0 2 0 0 2 2 2 0 zinc-ribbons Zn-ribbon_8 PF09723.10 KFP05504.1 - 0.072 13.2 3.6 11 6.2 0.1 3.4 3 0 0 3 3 3 0 Zinc ribbon domain HypA PF01155.19 KFP05504.1 - 0.29 11.2 3.4 0.29 11.2 0.3 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 KFP05504.1 - 0.5 9.8 7.0 2.2 7.8 0.3 2.8 3 0 0 3 3 3 0 zinc-ribbon domain CpXC PF14353.6 KFP05504.1 - 0.53 10.3 3.2 0.44 10.6 0.5 2.2 2 1 0 2 2 2 0 CpXC protein DZR PF12773.7 KFP05504.1 - 2.1 8.5 6.4 1.4 9.0 2.5 2.6 2 1 0 2 2 2 0 Double zinc ribbon UPF0547 PF10571.9 KFP05504.1 - 5 7.3 6.6 3.1 7.9 0.3 3.0 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Ig_3 PF13927.6 KFP05505.1 - 2.1e-30 105.1 7.0 1.7e-14 54.2 0.1 3.5 4 0 0 4 4 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFP05505.1 - 7.7e-26 90.2 0.7 2.1e-10 40.8 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFP05505.1 - 1.5e-25 89.1 0.1 3e-11 43.2 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 KFP05505.1 - 2e-24 85.5 0.7 3.9e-10 39.8 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFP05505.1 - 4.9e-19 68.5 3.8 1.1e-07 32.0 0.1 4.5 3 1 1 4 4 4 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP05505.1 - 1.5e-12 47.4 0.1 2.6e-10 40.2 0.0 3.2 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFP05505.1 - 1.9e-05 24.7 0.0 0.19 11.8 0.0 2.6 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Adeno_E3_CR1 PF02440.15 KFP05505.1 - 0.00062 19.5 0.6 0.18 11.6 0.0 3.0 3 0 0 3 3 2 1 Adenovirus E3 region protein CR1 Syndecan PF01034.20 KFP05505.1 - 0.013 15.4 0.0 0.53 10.2 0.1 2.4 2 0 0 2 2 2 0 Syndecan domain C2-set PF05790.15 KFP05505.1 - 0.017 15.3 0.1 29 4.9 0.0 4.1 4 0 0 4 4 4 0 Immunoglobulin C2-set domain C1-set PF07654.15 KFP05505.1 - 0.018 15.4 0.4 0.38 11.2 0.0 3.0 3 0 0 3 3 3 0 Immunoglobulin C1-set domain Ig_C17orf99 PF17736.1 KFP05505.1 - 0.066 13.3 0.0 0.58 10.2 0.0 2.6 3 1 0 3 3 3 0 C17orf99 Ig domain V-set_2 PF15910.5 KFP05505.1 - 0.16 12.1 1.3 3.7 7.7 0.1 3.0 2 1 1 3 3 3 0 ICOS V-set domain DUF3439 PF11921.8 KFP05505.1 - 0.49 10.4 9.4 1.1 9.3 9.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glycoprotein PF03409.15 KFP05505.1 - 2 7.2 8.1 6 5.6 0.1 2.2 2 0 0 2 2 2 0 Transmembrane glycoprotein RNase_T PF00929.24 KFP05506.1 - 1.3e-27 97.4 0.0 1.6e-27 97.0 0.0 1.1 1 0 0 1 1 1 1 Exonuclease RRM_1 PF00076.22 KFP05507.1 - 6.9e-09 35.4 0.0 1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-H2C2_2 PF13465.6 KFP05508.1 - 1.5e-36 123.1 47.2 9.8e-07 28.9 1.2 9.5 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP05508.1 - 7.5e-30 101.0 58.0 0.00016 22.2 1.8 9.5 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP05508.1 - 4.8e-27 92.9 59.7 0.00023 21.4 2.6 9.4 9 0 0 9 9 9 8 Zinc finger, C2H2 type BTB PF00651.31 KFP05508.1 - 9.7e-26 90.2 3.0 1.9e-25 89.2 3.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_6 PF13912.6 KFP05508.1 - 1.8e-16 59.7 54.0 8.2e-06 25.7 1.0 9.8 10 0 0 10 10 10 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP05508.1 - 2.4e-16 59.6 34.0 0.00015 21.9 0.4 9.8 10 0 0 10 10 10 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP05508.1 - 2.5e-14 53.1 42.2 0.00017 21.8 0.4 9.5 9 0 0 9 9 9 4 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 KFP05508.1 - 0.0081 16.9 23.6 0.82 10.5 1.8 5.1 1 1 3 4 4 4 2 zinc-ribbon family zf-C2H2_8 PF15909.5 KFP05508.1 - 0.01 16.1 25.8 2.3 8.6 0.6 4.8 1 1 4 5 5 5 0 C2H2-type zinc ribbon Endonuclease_7 PF02945.15 KFP05508.1 - 0.013 15.4 1.3 0.013 15.4 1.3 3.9 2 2 2 4 4 4 0 Recombination endonuclease VII zf_UBZ PF18439.1 KFP05508.1 - 0.019 14.6 35.3 0.14 11.8 0.1 8.0 9 0 0 9 9 9 0 Ubiquitin-Binding Zinc Finger DZR PF12773.7 KFP05508.1 - 0.023 14.7 28.6 4.1 7.5 2.9 5.2 2 1 1 3 3 3 0 Double zinc ribbon zf-C2H2_2 PF12756.7 KFP05508.1 - 0.024 15.0 42.2 0.2 12.0 0.5 8.1 1 1 7 8 8 8 0 C2H2 type zinc-finger (2 copies) MIX PF18529.1 KFP05508.1 - 0.027 14.2 0.1 0.054 13.2 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial membrane-anchored proteins zf-C2H2_11 PF16622.5 KFP05508.1 - 0.028 14.2 1.4 0.028 14.2 1.4 7.7 8 0 0 8 8 8 0 zinc-finger C2H2-type zf-MYST PF17772.1 KFP05508.1 - 0.27 10.9 21.5 0.68 9.6 0.5 6.3 6 3 1 7 7 7 0 MYST family zinc finger domain DUF3268 PF11672.8 KFP05508.1 - 2.9 8.2 18.9 4.5 7.6 0.2 4.6 4 1 1 5 5 5 0 zinc-finger-containing domain HypA PF01155.19 KFP05508.1 - 7.1 6.7 20.5 27 4.8 4.8 4.4 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Neur_chan_LBD PF02931.23 KFP05509.1 - 1.4e-54 184.8 4.0 1.8e-54 184.5 4.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP05509.1 - 1.2e-30 107.4 2.0 2.1e-30 106.5 2.0 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region UCH PF00443.29 KFP05510.1 - 2.6e-49 168.1 0.5 4.5e-49 167.3 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP05510.1 - 0.14 11.7 11.5 0.052 13.1 2.3 3.8 2 2 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 KFP05510.1 - 0.65 9.9 2.5 0.51 10.2 0.2 2.0 2 0 0 2 2 2 0 UBA-like domain DUF3322 PF11795.8 KFP05510.1 - 1.2 9.1 5.7 0.72 9.8 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) PMP22_Claudin PF00822.20 KFP05511.1 - 2.2e-14 53.7 0.3 2.5e-14 53.5 0.3 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP05511.1 - 0.00032 20.5 6.1 0.024 14.4 6.1 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction IRK_C PF17655.1 KFP05512.1 - 3.9e-72 241.5 0.0 5.3e-72 241.1 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFP05512.1 - 6.8e-53 178.3 2.7 1e-52 177.8 2.7 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ufd2P_core PF10408.9 KFP05513.1 - 1.6e-160 535.8 11.3 2.5e-160 535.1 11.3 1.3 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KFP05513.1 - 2e-32 111.2 0.6 6.7e-32 109.5 0.6 2.0 1 0 0 1 1 1 1 U-box domain ATP-synt_G PF04718.15 KFP05514.1 - 6.1e-24 84.8 0.0 7e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit FYRC PF05965.14 KFP05515.1 - 5.3e-21 74.6 0.0 1.7e-20 73.0 0.0 2.0 1 0 0 1 1 1 1 F/Y rich C-terminus SET PF00856.28 KFP05515.1 - 7.8e-21 75.2 0.7 7.8e-21 75.2 0.7 4.3 4 0 0 4 4 4 1 SET domain FYRN PF05964.14 KFP05515.1 - 2.4e-16 59.3 0.2 6.3e-16 58.0 0.2 1.8 1 0 0 1 1 1 1 F/Y-rich N-terminus PHD PF00628.29 KFP05515.1 - 1.3e-14 53.8 55.6 1.5e-08 34.4 12.0 5.9 5 1 2 7 7 7 3 PHD-finger zf-CXXC PF02008.20 KFP05515.1 - 2.5e-13 49.8 24.3 2.5e-13 49.8 24.3 5.4 5 0 0 5 5 5 1 CXXC zinc finger domain zf-HC5HC2H PF13771.6 KFP05515.1 - 2.9e-10 40.3 11.0 2.9e-10 40.3 11.0 5.8 4 1 1 5 5 5 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFP05515.1 - 8.7e-09 35.5 10.1 8.7e-09 35.5 10.1 5.3 4 1 1 5 5 5 1 PHD-zinc-finger like domain PHD_2 PF13831.6 KFP05515.1 - 0.00014 21.3 23.5 0.018 14.5 2.5 4.2 3 0 0 3 3 3 2 PHD-finger Bromodomain PF00439.25 KFP05515.1 - 0.0091 16.0 0.0 0.64 10.1 0.0 2.7 2 0 0 2 2 2 1 Bromodomain PHD_4 PF16866.5 KFP05515.1 - 0.25 11.4 41.6 0.015 15.4 10.1 4.5 2 1 1 3 3 3 0 PHD-finger TPR_2 PF07719.17 KFP05516.1 - 0.0011 19.0 0.2 0.19 11.9 0.0 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFP05516.1 - 0.15 12.0 0.0 10 6.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Adap_comp_sub PF00928.21 KFP05518.1 - 2.2e-35 122.3 0.4 3.2e-35 121.8 0.4 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFP05518.1 - 5.6e-06 26.3 0.3 1e-05 25.5 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Dermcidin PF15291.6 KFP05518.1 - 0.072 13.6 0.3 0.13 12.8 0.3 1.5 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide MFS_1 PF07690.16 KFP05519.1 - 7e-39 133.7 31.6 9.6e-39 133.3 26.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP05519.1 - 2.1 7.1 36.5 0.11 11.4 10.6 4.0 2 2 0 4 4 4 0 Sugar (and other) transporter Sybindin PF04099.12 KFP05520.1 - 5.5e-50 169.0 0.0 6.1e-50 168.9 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KFP05520.1 - 6.3e-08 32.8 0.0 7.9e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Ribosomal_S25 PF03297.15 KFP05521.1 - 1.3e-49 166.6 3.2 1.3e-49 166.6 3.2 1.3 1 1 0 1 1 1 1 S25 ribosomal protein Mt_ATP-synt_D PF05873.12 KFP05521.1 - 0.031 14.1 0.2 0.041 13.7 0.2 1.1 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) AIPR PF10592.9 KFP05521.1 - 0.097 12.3 0.6 0.12 12.0 0.6 1.2 1 1 0 1 1 1 0 AIPR protein TrmB PF01978.19 KFP05521.1 - 0.13 12.1 0.2 0.3 11.0 0.1 1.7 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB CCDC84 PF14968.6 KFP05522.1 - 7e-44 150.9 4.9 7.8e-44 150.7 4.9 1.0 1 0 0 1 1 1 1 Coiled coil protein 84 Forkhead PF00250.18 KFP05523.1 - 9.9e-29 99.5 0.0 1.2e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Forkhead domain DUF3872 PF12988.7 KFP05523.1 - 0.059 13.2 0.0 0.09 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3872) DEAD PF00270.29 KFP05525.1 - 1e-41 142.6 1.5 2.5e-41 141.4 0.4 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP05525.1 - 2.4e-28 98.7 0.7 3.5e-27 94.9 0.5 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KFP05525.1 - 0.00073 19.0 0.2 0.0012 18.2 0.2 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 KFP05525.1 - 0.0013 18.7 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit VPS11_C PF12451.8 KFP05526.1 - 1.7e-18 66.6 1.0 5.1e-18 65.0 0.3 2.3 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.20 KFP05526.1 - 2.1e-16 60.1 13.7 1.7e-15 57.1 3.1 2.9 2 1 0 2 2 2 2 Region in Clathrin and VPS zf-C3HC4_2 PF13923.6 KFP05526.1 - 3e-09 36.6 8.2 6.7e-09 35.4 8.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP05526.1 - 3.4e-08 33.7 8.8 8.7e-08 32.4 8.8 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFP05526.1 - 3.9e-05 23.8 6.7 0.00011 22.4 6.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFP05526.1 - 0.00015 21.6 8.0 0.00033 20.5 8.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 KFP05526.1 - 0.001 19.0 9.4 0.0026 17.8 9.4 1.7 1 0 0 1 1 1 1 Zinc-finger zf-RING_5 PF14634.6 KFP05526.1 - 0.0026 17.7 8.3 0.0066 16.4 8.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFP05526.1 - 0.0095 15.9 9.5 0.028 14.4 9.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFP05526.1 - 0.014 15.3 5.2 0.028 14.3 5.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DivIC PF04977.15 KFP05526.1 - 0.018 14.8 3.9 0.053 13.3 3.9 1.8 1 0 0 1 1 1 0 Septum formation initiator Paralemmin PF03285.15 KFP05526.1 - 0.034 13.7 0.4 0.057 13.0 0.4 1.3 1 0 0 1 1 1 0 Paralemmin zf-ANAPC11 PF12861.7 KFP05526.1 - 0.038 14.0 1.8 0.13 12.3 1.8 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KFP05526.1 - 0.16 12.1 9.0 0.46 10.7 9.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DLP_helical PF18709.1 KFP05526.1 - 0.17 11.0 2.4 0.46 9.6 2.4 1.6 1 0 0 1 1 1 0 Dynamin-like helical domain zf-RING-like PF08746.11 KFP05526.1 - 0.23 11.8 7.2 0.75 10.2 7.2 2.0 1 0 0 1 1 1 0 RING-like domain zf-RING_11 PF17123.5 KFP05526.1 - 0.28 11.0 8.5 0.77 9.6 8.5 1.9 1 0 0 1 1 1 0 RING-like zinc finger TPR_11 PF13414.6 KFP05526.1 - 0.41 10.4 4.4 1.7 8.4 0.0 3.9 5 0 0 5 5 5 0 TPR repeat GHL13 PF14883.6 KFP05526.1 - 0.73 8.8 5.1 0.99 8.4 0.1 2.8 3 0 0 3 3 3 0 Hypothetical glycosyl hydrolase family 13 WASH_WAHD PF11945.8 KFP05526.1 - 1 8.9 5.5 3.4 7.1 0.7 2.2 2 0 0 2 2 2 0 WAHD domain of WASH complex Prefoldin_2 PF01920.20 KFP05526.1 - 2 8.4 11.9 6.1 6.8 4.4 3.7 3 0 0 3 3 3 0 Prefoldin subunit Zn_ribbon_17 PF17120.5 KFP05526.1 - 6.8 6.4 10.5 2.3 7.9 6.3 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Porphobil_deam PF01379.20 KFP05527.1 - 1.4e-76 256.6 0.0 1.8e-76 256.2 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KFP05527.1 - 8.1e-20 71.0 0.1 4.9e-19 68.5 0.0 2.2 1 1 1 2 2 2 1 Porphobilinogen deaminase, C-terminal domain CUE PF02845.16 KFP05527.1 - 0.0031 17.2 0.0 0.33 10.7 0.0 2.7 2 0 0 2 2 2 1 CUE domain MGS PF02142.22 KFP05527.1 - 0.025 14.7 0.0 0.061 13.5 0.0 1.7 1 0 0 1 1 1 0 MGS-like domain SMP_C2CD2L PF18696.1 KFP05528.1 - 1.7e-45 154.5 0.9 4e-45 153.4 0.9 1.7 1 0 0 1 1 1 1 Synaptotagmin-like, mitochondrial and lipid-binding domain Nuf2 PF03800.14 KFP05529.1 - 1.5e-34 119.1 6.8 2.4e-34 118.4 0.1 2.9 3 0 0 3 3 3 1 Nuf2 family SAVED PF18145.1 KFP05529.1 - 0.008 16.0 5.0 1.1 9.1 0.1 3.2 3 0 0 3 3 3 2 SMODS-associated and fused to various effectors sensor domain Filament PF00038.21 KFP05529.1 - 0.014 15.0 47.0 0.014 15.0 13.1 4.0 1 1 3 4 4 4 0 Intermediate filament protein HMMR_N PF15905.5 KFP05529.1 - 0.13 11.7 56.1 0.88 9.0 20.6 2.3 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF2385 PF09539.10 KFP05529.1 - 0.17 12.4 3.3 0.37 11.3 0.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2385) G-gamma PF00631.22 KFP05529.1 - 0.24 11.4 4.6 1.1 9.4 0.1 3.1 2 0 0 2 2 2 0 GGL domain FAM76 PF16046.5 KFP05529.1 - 1.8 7.9 37.8 0.75 9.1 8.0 2.9 2 2 0 2 2 2 0 FAM76 protein Atg14 PF10186.9 KFP05529.1 - 1.9 7.5 42.5 0.37 9.8 18.3 2.5 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 COG5 PF10392.9 KFP05529.1 - 2.5 8.3 27.7 0.029 14.5 10.7 4.1 2 1 2 5 5 4 0 Golgi transport complex subunit 5 KASH_CCD PF14662.6 KFP05529.1 - 2.9 7.7 53.7 0.41 10.4 17.6 3.1 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH Fez1 PF06818.15 KFP05529.1 - 4 7.9 44.3 0.046 14.2 20.7 2.8 1 1 1 3 3 3 0 Fez1 ATG16 PF08614.11 KFP05529.1 - 4.4 7.5 45.4 0.069 13.4 26.0 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF724 PF05266.14 KFP05529.1 - 4.6 7.0 43.1 0.63 9.8 17.4 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF724) DUF3584 PF12128.8 KFP05529.1 - 5.3 4.4 47.6 8 3.8 17.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Complex1_49kDa PF00346.19 KFP05529.1 - 7.2 5.6 12.1 0.17 10.9 1.2 2.7 3 0 0 3 3 3 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit ApoLp-III PF07464.11 KFP05529.1 - 9 6.4 32.6 28 4.8 7.0 3.6 1 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF1664 PF07889.12 KFP05529.1 - 9.9 6.2 29.2 0.53 10.3 5.0 3.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) MAPEG PF01124.18 KFP05530.1 - 1.3e-22 80.1 1.3 1.6e-22 79.8 1.3 1.1 1 0 0 1 1 1 1 MAPEG family DmsC PF04976.12 KFP05530.1 - 0.049 13.1 0.2 0.085 12.3 0.2 1.4 1 0 0 1 1 1 0 DMSO reductase anchor subunit (DmsC) Aldedh PF00171.22 KFP05531.1 - 1.8e-174 580.6 0.0 2.1e-174 580.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family EMC3_TMCO1 PF01956.16 KFP05532.1 - 7.2e-38 130.0 0.9 8.1e-38 129.8 0.9 1.0 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like TRAM1 PF08390.11 KFP05532.1 - 0.0027 17.3 0.0 0.005 16.5 0.0 1.4 1 0 0 1 1 1 1 TRAM1-like protein DUF2368 PF10166.9 KFP05532.1 - 0.013 15.1 0.1 0.02 14.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) DivIC PF04977.15 KFP05532.1 - 0.11 12.2 0.6 0.11 12.2 0.6 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF4257 PF14074.6 KFP05532.1 - 0.12 12.6 0.1 0.24 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4257) DUF3671 PF12420.8 KFP05532.1 - 0.18 11.9 2.8 0.16 12.0 1.1 1.7 1 1 1 2 2 2 0 Protein of unknown function XhlA PF10779.9 KFP05532.1 - 0.86 9.9 6.5 5 7.4 6.5 2.0 1 1 0 1 1 1 0 Haemolysin XhlA Atg14 PF10186.9 KFP05532.1 - 1.7 7.6 6.6 2.3 7.2 6.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1090 PF06476.12 KFP05532.1 - 3.3 7.9 15.1 1.2 9.3 12.9 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) PRK PF00485.18 KFP05533.1 - 3.3e-47 160.8 0.8 3.8e-47 160.6 0.8 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family DUF826 PF05696.11 KFP05533.1 - 0.088 12.9 0.0 6.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF826) Kelch_1 PF01344.25 KFP05534.1 - 9.9e-92 300.3 21.1 3.5e-17 61.7 0.5 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFP05534.1 - 4.1e-54 179.2 7.8 4.5e-10 39.5 0.0 6.4 2 2 4 6 6 6 6 Kelch motif BACK PF07707.15 KFP05534.1 - 2.5e-38 130.3 0.5 4.2e-38 129.6 0.1 1.6 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 KFP05534.1 - 5.3e-36 122.4 8.0 3.4e-06 27.0 0.1 6.2 2 2 4 6 6 6 6 Galactose oxidase, central domain BTB PF00651.31 KFP05534.1 - 9.2e-33 112.8 0.7 1.5e-32 112.1 0.3 1.6 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 KFP05534.1 - 2.1e-31 106.7 7.0 1.2e-06 28.2 0.2 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KFP05534.1 - 1e-29 102.2 16.7 9.3e-06 25.8 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP05534.1 - 8.3e-06 25.7 8.8 1.9 8.5 0.1 5.9 6 0 0 6 6 6 3 Kelch motif XPA_C PF05181.12 KFP05534.1 - 0.043 13.8 0.3 7.8 6.6 0.0 3.3 4 0 0 4 4 4 0 XPA protein C-terminus Glu_cyclase_2 PF05096.12 KFP05534.1 - 0.085 12.3 0.0 31 3.9 0.0 2.7 1 1 0 3 3 3 0 Glutamine cyclotransferase PQQ_3 PF13570.6 KFP05534.1 - 5.2 7.7 16.8 1.1 9.9 0.5 4.8 5 0 0 5 5 5 0 PQQ-like domain CENP-L PF13092.6 KFP05535.1 - 1.2e-31 110.1 0.0 1.6e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Ge1_WD40 PF16529.5 KFP05535.1 - 0.069 12.1 0.1 0.19 10.6 0.0 1.7 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein tRNA-synt_2 PF00152.20 KFP05536.1 - 1.4e-95 320.0 0.0 1.8e-95 319.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GAD PF02938.14 KFP05536.1 - 2e-12 47.2 0.0 5.6e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 GAD domain tRNA_anti-codon PF01336.25 KFP05536.1 - 1.7e-08 34.3 0.0 3.2e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RGS PF00615.19 KFP05537.1 - 4.9e-38 130.0 2.0 6.3e-38 129.7 2.0 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain DNA_gyraseB_C PF00986.21 KFP05537.1 - 0.053 13.7 0.0 11 6.3 0.0 2.3 2 0 0 2 2 2 0 DNA gyrase B subunit, carboxyl terminus Arteri_nsp7a PF16749.5 KFP05537.1 - 0.11 12.7 0.1 0.15 12.2 0.1 1.2 1 0 0 1 1 1 0 Arterivirus nonstructural protein 7 alpha RGS PF00615.19 KFP05538.1 - 6.7e-37 126.4 3.7 8.4e-37 126.1 3.7 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS PF00615.19 KFP05540.1 - 2.3e-08 34.3 0.0 0.0016 18.7 0.0 3.5 4 0 0 4 4 4 2 Regulator of G protein signaling domain Gln-synt_C PF00120.24 KFP05541.1 - 1.4e-17 63.7 0.0 1.9e-12 46.9 0.0 2.2 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KFP05541.1 - 3e-14 52.5 0.0 5.2e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain F-box-like PF12937.7 KFP05541.1 - 0.095 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 F-box-like AhpC-TSA PF00578.21 KFP05542.1 - 1.6e-13 50.6 0.0 1.7e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFP05542.1 - 1.1e-05 25.2 0.0 1.1e-05 25.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin Syntaxin-6_N PF09177.11 KFP05543.1 - 5.7e-31 107.0 0.9 5.7e-31 107.0 0.9 2.8 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KFP05543.1 - 1.7e-13 50.4 1.5 4.4e-13 49.0 1.5 1.8 1 0 0 1 1 1 1 SNARE domain Prominin PF05478.11 KFP05543.1 - 0.0053 14.8 4.8 0.026 12.5 0.6 1.9 1 1 0 2 2 2 2 Prominin FliD_C PF07195.12 KFP05543.1 - 0.048 13.1 3.1 2.7 7.3 0.0 2.4 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Use1 PF09753.9 KFP05543.1 - 0.052 13.3 4.3 0.069 12.9 4.3 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 APG17 PF04108.12 KFP05543.1 - 0.063 12.4 8.6 0.045 12.9 1.8 2.3 1 1 1 2 2 2 0 Autophagy protein Apg17 FAM167 PF11652.8 KFP05543.1 - 0.11 12.9 1.5 10 6.7 0.0 2.7 2 1 0 2 2 2 0 FAM167 Ran-binding PF05508.11 KFP05543.1 - 0.33 9.9 4.8 0.16 10.9 0.9 1.9 2 0 0 2 2 2 0 RanGTP-binding protein DUF1664 PF07889.12 KFP05543.1 - 0.43 10.6 6.5 9.5 6.3 2.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 KFP05543.1 - 4 6.9 8.2 11 5.5 8.2 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit KxDL PF10241.9 KFP05543.1 - 4 7.8 8.1 2.4 8.5 3.1 2.7 3 1 0 3 3 3 0 Uncharacterized conserved protein EXS PF03124.14 KFP05544.1 - 4.1e-107 358.3 24.6 5.4e-107 357.9 24.6 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KFP05544.1 - 5.4e-20 72.7 14.2 3.3e-14 53.6 3.9 2.2 1 1 1 2 2 2 2 SPX domain Ank_4 PF13637.6 KFP05545.1 - 2.8e-19 69.2 0.9 3.9e-14 52.8 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP05545.1 - 1.8e-16 60.5 0.1 3.2e-16 59.7 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFP05545.1 - 2.3e-15 56.2 0.1 9.9e-07 28.9 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KFP05545.1 - 3.5e-15 55.9 0.1 2e-10 40.7 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) ACBP PF00887.19 KFP05545.1 - 1.2e-14 54.2 0.1 2.2e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_3 PF13606.6 KFP05545.1 - 8.7e-14 50.3 0.3 8.3e-05 22.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat GBP_repeat PF02526.14 KFP05545.1 - 0.12 12.1 0.0 6.4 6.6 0.0 3.0 3 0 0 3 3 3 0 Glycophorin-binding protein LIM PF00412.22 KFP05546.1 - 2.4e-32 110.9 19.5 1.1e-16 60.8 2.9 2.2 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 KFP05546.1 - 1.7e-21 75.8 2.4 2.8e-21 75.1 2.4 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP05546.1 - 9.9e-05 22.2 0.0 0.00026 20.8 0.0 1.8 1 1 0 1 1 1 1 Homeobox KN domain Furin-like_2 PF15913.5 KFP05546.1 - 0.0043 17.2 7.1 0.0043 17.2 7.1 2.1 1 1 1 2 2 2 1 Furin-like repeat, cysteine-rich PHF5 PF03660.14 KFP05546.1 - 1.8 8.8 10.2 0.094 12.9 3.3 2.1 1 1 1 2 2 2 0 PHF5-like protein FAD_SOX PF18371.1 KFP05547.1 - 1.7e-42 144.0 0.0 3.3e-42 143.1 0.0 1.5 1 0 0 1 1 1 1 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase QSOX_Trx1 PF18108.1 KFP05547.1 - 2.4e-42 143.5 0.0 7.2e-42 142.0 0.0 1.8 2 0 0 2 2 2 1 QSOX Trx-like domain Evr1_Alr PF04777.13 KFP05547.1 - 2.2e-25 89.0 0.2 1.7e-24 86.2 0.1 2.2 2 0 0 2 2 2 1 Erv1 / Alr family Thioredoxin PF00085.20 KFP05547.1 - 0.00048 20.1 0.0 0.0096 15.9 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 KFP05547.1 - 0.00076 19.9 0.0 15 6.1 0.0 3.6 3 1 0 3 3 3 1 Thioredoxin-like domain HyaE PF07449.11 KFP05547.1 - 0.072 13.1 0.0 4.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Zn-ribbon_8 PF09723.10 KFP05547.1 - 0.42 10.8 4.8 6.8 6.9 0.4 2.6 2 0 0 2 2 2 0 Zinc ribbon domain CAP_GLY PF01302.25 KFP05548.1 - 2e-21 75.7 0.2 3.6e-21 75.0 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain Glyco_hydro_92 PF07971.12 KFP05548.1 - 0.33 9.8 5.3 0.11 11.4 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 92 LAP1C PF05609.12 KFP05549.1 - 2.6e-103 346.6 0.2 2.8e-103 346.4 0.2 1.0 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) Stap_Strp_tox_C PF02876.17 KFP05549.1 - 0.024 14.9 0.1 0.053 13.8 0.1 1.6 1 1 0 1 1 1 0 Staphylococcal/Streptococcal toxin, beta-grasp domain LAP1C PF05609.12 KFP05550.1 - 1.9e-95 320.6 0.1 2.2e-95 320.5 0.1 1.0 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) F5_F8_type_C PF00754.25 KFP05551.1 - 1.3e-25 89.9 2.8 1.6e-25 89.7 0.5 2.0 2 0 0 2 2 2 1 F5/8 type C domain CUB PF00431.20 KFP05551.1 - 2.2e-24 85.9 0.0 3.8e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 CUB domain LCCL PF03815.19 KFP05551.1 - 1.7e-13 50.5 0.6 3.5e-13 49.5 0.1 1.8 2 0 0 2 2 2 1 LCCL domain Syndecan PF01034.20 KFP05551.1 - 0.0046 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Syndecan domain DUF4448 PF14610.6 KFP05551.1 - 0.034 13.9 0.2 0.058 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) CDC50 PF03381.15 KFP05552.1 - 7.2e-87 291.5 2.6 9.3e-87 291.1 2.6 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CMS1 PF14617.6 KFP05553.1 - 1.2e-28 100.1 1.5 2.9e-28 98.9 1.5 1.5 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KFP05553.1 - 1.3e-06 28.3 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Herpes_ori_bp PF02399.15 KFP05553.1 - 0.003 15.7 0.2 0.0031 15.7 0.2 1.0 1 0 0 1 1 1 1 Origin of replication binding protein CortBP2 PF09727.9 KFP05554.1 - 7.6e-61 205.4 29.1 7.6e-61 205.4 29.1 7.2 1 1 6 7 7 7 3 Cortactin-binding protein-2 Occludin_ELL PF07303.13 KFP05554.1 - 0.0016 19.2 7.9 0.0016 19.2 7.9 9.0 3 3 7 10 10 10 3 Occludin homology domain RabGAP-TBC PF00566.18 KFP05555.1 - 9.1e-21 74.5 1.6 1.7e-20 73.6 1.6 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.20 KFP05555.1 - 1.3e-07 32.1 0.0 3.9e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain CN_hydrolase PF00795.22 KFP05556.1 - 2.9e-65 220.2 0.0 3.3e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TPR_1 PF00515.28 KFP05557.1 - 5.6e-37 124.1 23.0 4.6e-07 29.4 0.1 10.1 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 KFP05557.1 - 1.1e-31 106.3 24.5 3.2e-05 23.7 0.1 10.6 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_11 PF13414.6 KFP05557.1 - 1.2e-27 95.3 11.4 3.2e-06 26.7 0.1 7.7 6 2 2 8 8 8 6 TPR repeat TPR_8 PF13181.6 KFP05557.1 - 1.2e-27 93.7 18.0 0.00016 21.6 0.0 9.9 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_14 PF13428.6 KFP05557.1 - 3.7e-21 74.0 7.4 0.0013 19.4 0.0 8.7 4 2 6 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 KFP05557.1 - 4.3e-18 65.4 10.4 8.5e-05 22.8 0.1 7.0 3 2 4 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFP05557.1 - 1.2e-16 59.7 19.8 0.0037 17.5 0.1 9.7 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFP05557.1 - 1.1e-12 47.8 8.2 1.3 9.8 0.0 9.1 9 1 0 9 9 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFP05557.1 - 2e-11 43.9 3.4 0.0012 19.0 0.3 6.9 4 2 1 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP05557.1 - 2.2e-10 40.9 14.9 0.041 14.4 0.1 6.7 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFP05557.1 - 1.4e-08 35.3 3.7 3.9 8.2 0.0 6.9 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFP05557.1 - 3.2e-08 33.0 2.8 0.1 12.7 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF5569 PF17729.1 KFP05557.1 - 2.9e-06 27.3 2.8 1.2e-05 25.3 0.2 2.6 2 1 1 3 3 3 1 Family of unknown function (DUF5569) MIT PF04212.18 KFP05557.1 - 2.3e-05 24.4 8.8 0.21 11.7 0.6 5.6 4 1 0 4 4 4 2 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 KFP05557.1 - 0.00078 19.2 16.9 4.8 7.2 0.0 6.8 6 1 1 7 7 6 1 Tetratricopeptide repeat NRBF2_MIT PF17169.4 KFP05557.1 - 0.0032 17.7 1.0 0.031 14.5 0.1 2.9 2 0 0 2 2 2 1 MIT domain of nuclear receptor-binding factor 2 Hypoth_Ymh PF09509.10 KFP05557.1 - 0.019 14.9 0.7 6.4 6.7 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (Hypoth_ymh) TPR_MalT PF17874.1 KFP05557.1 - 0.028 13.8 3.9 0.095 12.1 0.1 3.1 3 3 0 3 3 3 0 MalT-like TPR region PPR PF01535.20 KFP05557.1 - 0.044 14.1 0.3 7.5 7.0 0.0 3.6 3 0 0 3 3 2 0 PPR repeat RPN7 PF10602.9 KFP05557.1 - 0.082 12.6 10.9 0.048 13.4 0.5 3.8 3 1 1 4 4 4 0 26S proteasome subunit RPN7 SHNi-TPR PF10516.9 KFP05557.1 - 0.087 12.3 0.4 4.2 6.9 0.0 4.0 4 1 1 5 5 5 0 SHNi-TPR HrpB1_HrpK PF09613.10 KFP05557.1 - 0.12 12.0 3.1 6.8 6.3 0.1 3.6 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) Mad3_BUB1_I PF08311.12 KFP05557.1 - 0.27 11.2 8.9 0.59 10.1 0.2 4.3 4 2 0 4 4 4 0 Mad3/BUB1 homology region 1 ANAPC3 PF12895.7 KFP05557.1 - 3.1 8.1 23.3 6.8 7.0 0.2 5.8 4 3 2 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 LNP1 PF15419.6 KFP05558.1 - 4.9e-64 215.8 25.9 7.4e-64 215.3 25.9 1.3 1 1 0 1 1 1 1 Leukemia NUP98 fusion partner 1 DUF716 PF04819.12 KFP05559.1 - 1.2e-34 118.9 13.6 2.2e-34 118.1 13.6 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF716) 7tm_2 PF00002.24 KFP05560.1 - 3.9e-39 134.4 16.0 6.9e-39 133.6 16.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 KFP05560.1 - 1.8e-10 41.2 8.5 2.4e-10 40.8 5.5 2.4 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif EGF PF00008.27 KFP05560.1 - 0.16 12.3 4.7 0.39 11.1 4.7 1.6 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 KFP05560.1 - 0.36 10.9 4.1 0.8 9.8 4.1 1.6 1 0 0 1 1 1 0 Tenascin EGF domain DUF4131 PF13567.6 KFP05560.1 - 5 6.8 5.7 3.4 7.3 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) PB1 PF00564.24 KFP05561.1 - 2.9e-11 43.2 0.4 5.2e-11 42.3 0.2 1.5 2 0 0 2 2 2 1 PB1 domain fn3 PF00041.21 KFP05562.1 - 3.8e-16 59.2 8.6 3.5e-10 40.1 0.9 3.8 3 1 0 3 3 3 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFP05562.1 - 7.8e-08 32.8 6.8 0.0023 18.5 0.4 3.3 3 1 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFP05562.1 - 7.4e-05 23.0 0.5 0.34 11.2 0.0 3.5 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 KFP05562.1 - 0.1 13.0 1.5 3 8.3 0.0 3.1 3 1 0 3 3 3 0 Uncharacterised conserved protein (DUF2369) SEA PF01390.20 KFP05564.1 - 7.7e-25 87.0 4.4 2.2e-16 59.8 0.5 3.1 3 0 0 3 3 3 2 SEA domain EGF PF00008.27 KFP05564.1 - 0.00035 20.8 14.9 0.00035 20.8 4.0 2.4 2 0 0 2 2 2 2 EGF-like domain DUF4214 PF13946.6 KFP05564.1 - 0.0049 16.9 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4214) Dam PF05869.11 KFP05564.1 - 0.044 13.4 0.1 0.091 12.3 0.1 1.4 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) Arb2 PF09757.9 KFP05565.1 - 1.7e-08 33.9 0.2 2.4e-08 33.4 0.2 1.3 1 1 0 1 1 1 1 Arb2 domain PGAP1 PF07819.13 KFP05565.1 - 0.039 13.7 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 KFP05565.1 - 0.12 11.9 0.2 2.6 7.5 0.1 2.1 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DIM1 PF02966.16 KFP05566.1 - 3.4e-55 185.4 0.1 3.9e-55 185.2 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KFP05566.1 - 4.5e-06 26.6 0.0 5.8e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin tRNA_m1G_MT PF01746.21 KFP05567.1 - 2.4e-33 115.5 1.0 3.1e-33 115.1 0.1 1.6 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase PCNP PF15473.6 KFP05568.1 - 2.4e-68 229.8 12.5 2.7e-68 229.6 12.5 1.0 1 0 0 1 1 1 1 PEST, proteolytic signal-containing nuclear protein family SPATIAL PF15256.6 KFP05568.1 - 0.058 13.7 1.0 0.095 13.0 0.1 1.5 1 1 1 2 2 2 0 SPATIAL zf-H2C2_2 PF13465.6 KFP05569.1 - 3.2e-49 163.3 86.2 5.7e-08 32.8 0.2 13.9 14 0 0 14 14 14 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFP05569.1 - 6.7e-42 139.7 94.7 0.00018 21.8 0.9 13.3 13 0 0 13 13 13 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP05569.1 - 1.3e-39 131.4 89.0 0.00068 20.3 1.5 13.6 13 0 0 13 13 13 12 C2H2-type zinc finger BTB PF00651.31 KFP05569.1 - 2.3e-22 79.3 2.0 5e-22 78.2 2.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_6 PF13912.6 KFP05569.1 - 2.8e-15 55.9 94.2 0.0001 22.2 0.6 12.0 13 1 0 13 13 12 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP05569.1 - 8.5e-12 45.0 59.9 0.00086 19.5 0.6 12.6 12 1 0 12 12 11 5 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFP05569.1 - 9.1e-08 32.3 49.8 0.001 19.3 0.7 8.1 4 2 3 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KFP05569.1 - 2.8e-05 24.4 69.6 0.41 11.0 0.6 11.8 4 2 10 14 14 14 6 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFP05569.1 - 8.3e-05 22.8 62.3 0.21 12.0 0.8 11.6 11 0 0 11 11 10 3 Zinc-finger of C2H2 type HNH_5 PF14279.6 KFP05569.1 - 0.0051 16.6 1.3 0.0051 16.6 1.3 7.4 9 1 0 9 9 7 1 HNH endonuclease zf-C2H2_9 PF16293.5 KFP05569.1 - 0.0083 15.9 15.7 9.7 6.1 0.1 7.7 6 2 2 8 8 8 0 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 KFP05569.1 - 0.019 14.7 59.9 0.045 13.5 0.0 11.5 12 0 0 12 12 12 0 zinc-finger C2H2-type Ta0938 PF11494.8 KFP05569.1 - 0.061 13.6 15.8 0.9 9.8 0.8 5.4 4 2 1 6 6 5 0 Ta0938 SNRNP27 PF08648.12 KFP05569.1 - 0.35 11.0 2.6 9.2 6.4 0.8 3.0 2 0 0 2 2 2 0 U4/U6.U5 small nuclear ribonucleoproteins zf-C2H2_8 PF15909.5 KFP05569.1 - 0.78 10.1 34.7 0.06 13.7 4.8 5.8 2 1 3 5 5 5 0 C2H2-type zinc ribbon zinc_ribbon_15 PF17032.5 KFP05569.1 - 0.79 10.5 44.4 3.6 8.4 1.3 8.4 3 1 6 9 9 9 0 zinc-ribbon family PhnA_Zn_Ribbon PF08274.12 KFP05569.1 - 0.8 9.7 8.6 7.1 6.7 0.0 5.8 6 1 0 6 6 5 0 PhnA Zinc-Ribbon ARS2 PF04959.13 KFP05569.1 - 2.7 8.3 16.5 0.2 12.0 1.7 4.8 4 0 0 4 4 4 0 Arsenite-resistance protein 2 Zn-ribbon_8 PF09723.10 KFP05569.1 - 4.5 7.5 54.5 1.1 9.5 1.2 9.9 6 5 3 9 9 8 0 Zinc ribbon domain Ribosomal_L24e PF01246.20 KFP05570.1 - 7.3e-33 112.6 0.7 7.3e-33 112.6 0.7 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e LRR_9 PF14580.6 KFP05571.1 - 3.3e-20 72.3 1.6 1.1e-15 57.6 0.0 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 KFP05571.1 - 6.2e-17 61.4 27.3 3.1e-05 24.2 3.9 4.9 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP05571.1 - 1.8e-12 46.8 28.2 2.1e-05 24.2 4.4 4.3 1 1 2 4 4 4 4 Leucine rich repeat IQ PF00612.27 KFP05571.1 - 0.0015 18.1 0.1 0.0031 17.2 0.1 1.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif LRR_1 PF00560.33 KFP05571.1 - 0.0096 16.3 9.4 2.5 9.0 0.2 5.8 3 1 1 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 KFP05571.1 - 0.056 13.5 15.5 0.3 11.3 0.5 6.2 6 0 0 6 6 6 0 Leucine Rich repeat Thyroglobulin_1 PF00086.18 KFP05573.1 - 1.3e-37 127.3 18.8 3e-19 68.5 4.5 2.8 2 0 0 2 2 2 2 Thyroglobulin type-1 repeat Thyroglob_assoc PF16597.5 KFP05573.1 - 3.7e-28 97.6 2.6 8.3e-28 96.5 2.6 1.6 1 0 0 1 1 1 1 Thyroglobulin_1 repeat associated disordered domain SPARC_Ca_bdg PF10591.9 KFP05573.1 - 1.5e-11 44.6 1.2 3.3e-11 43.5 0.1 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_2 PF07648.15 KFP05573.1 - 1.8e-07 31.2 4.2 1.8e-07 31.2 4.2 2.3 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.6 KFP05573.1 - 9e-06 26.0 0.1 0.00013 22.4 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP05573.1 - 5.5e-05 22.4 0.2 1.3 8.7 0.0 3.7 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 KFP05573.1 - 0.00013 21.6 0.3 1.4 9.0 0.1 3.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 KFP05573.1 - 0.017 14.6 2.0 0.12 11.9 0.0 3.2 4 0 0 4 4 4 0 EF hand Sulfotransfer_1 PF00685.27 KFP05574.1 - 1.2e-45 156.1 0.9 1.3e-45 156.0 0.9 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP05574.1 - 1.4e-07 32.1 0.0 1.9e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family DUF1266 PF06889.11 KFP05574.1 - 0.0014 18.7 0.4 0.0019 18.3 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1266) Dapper PF15268.6 KFP05575.1 - 6.3e-230 766.3 39.6 7.1e-230 766.1 39.6 1.0 1 0 0 1 1 1 1 Dapper DivIC PF04977.15 KFP05575.1 - 0.0022 17.7 1.1 0.93 9.3 0.1 2.5 2 0 0 2 2 2 2 Septum formation initiator PspA_IM30 PF04012.12 KFP05575.1 - 0.87 9.1 6.0 0.086 12.4 1.0 1.7 2 0 0 2 2 2 0 PspA/IM30 family Spc24 PF08286.11 KFP05575.1 - 1.3 9.3 5.7 7.9 6.8 0.6 2.8 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 DUF724 PF05266.14 KFP05575.1 - 2.5 7.9 4.8 1.5 8.6 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) APG6_N PF17675.1 KFP05575.1 - 4.8 7.7 7.2 34 5.0 2.1 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region FERM_M PF00373.18 KFP05576.1 - 1.7e-20 73.6 0.4 1.7e-20 73.6 0.4 1.7 2 0 0 2 2 2 1 FERM central domain FERM_C PF09380.10 KFP05576.1 - 4.6e-16 59.0 0.0 1.2e-15 57.7 0.0 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KFP05576.1 - 6.6e-13 48.4 0.0 1.5e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 FERM N-terminal domain Kinesin PF00225.23 KFP05577.1 - 9.3e-82 274.6 0.0 1.4e-46 158.9 0.0 2.2 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KFP05577.1 - 1.8e-39 135.1 0.0 3.8e-39 134.0 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding UNC-93 PF05978.16 KFP05579.1 - 2.3e-10 40.4 9.9 2.3e-10 40.4 9.9 3.3 2 2 1 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KFP05579.1 - 1.5e-08 34.0 31.2 4.6e-05 22.5 13.0 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CDH PF02611.15 KFP05579.1 - 0.1 12.2 0.0 0.38 10.3 0.0 1.8 2 0 0 2 2 2 0 CDP-diacylglycerol pyrophosphatase Ribonuclease_T2 PF00445.18 KFP05580.1 - 1.7e-49 168.5 3.9 2e-49 168.3 3.9 1.0 1 0 0 1 1 1 1 Ribonuclease T2 family Pkinase PF00069.25 KFP05581.1 - 4.9e-148 491.6 0.0 9.2e-75 251.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFP05581.1 - 8.5e-78 261.2 0.0 2e-41 142.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFP05581.1 - 1.3e-13 50.9 0.0 4.1e-06 26.3 0.0 2.7 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 KFP05581.1 - 2.2e-10 40.2 0.0 4.9e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.24 KFP05581.1 - 6.6e-08 33.1 1.6 2e-07 31.6 1.6 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 KFP05581.1 - 4.9e-07 28.9 0.0 0.006 15.4 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 KFP05581.1 - 4e-06 26.9 0.0 0.21 11.5 0.0 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFP05581.1 - 4.4e-05 22.6 0.0 0.028 13.4 0.0 2.2 2 0 0 2 2 2 2 Haspin like kinase domain FTA2 PF13095.6 KFP05581.1 - 4.8e-05 23.1 0.1 1.5 8.4 0.0 3.3 3 0 0 3 3 3 3 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 KFP05581.1 - 0.00088 18.9 0.0 0.19 11.2 0.0 2.5 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL RIO1 PF01163.22 KFP05581.1 - 0.005 16.4 0.2 0.36 10.4 0.0 2.6 3 0 0 3 3 3 1 RIO1 family MPC PF03650.13 KFP05583.1 - 1e-31 109.3 0.1 1.1e-31 109.2 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Got1 PF04178.12 KFP05584.1 - 3.4e-35 120.9 16.5 6.7e-35 119.9 15.0 1.8 1 1 1 2 2 2 2 Got1/Sft2-like family DUF4064 PF13273.6 KFP05584.1 - 0.0046 17.2 7.3 0.0098 16.2 1.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF4064) DUF3429 PF11911.8 KFP05584.1 - 0.47 10.7 9.2 0.041 14.2 4.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3429) DoxX_2 PF13564.6 KFP05584.1 - 0.76 9.9 9.6 1.8 8.7 3.6 2.1 1 1 1 2 2 2 0 DoxX-like family Bac_export_2 PF01312.19 KFP05584.1 - 0.79 8.9 4.1 2.9 7.0 4.1 1.8 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family FtsX PF02687.21 KFP05584.1 - 1.2 9.6 14.4 0.084 13.3 7.4 2.1 1 1 1 2 2 2 0 FtsX-like permease family DUF5090 PF17009.5 KFP05584.1 - 2.8 7.9 7.0 1.3 9.0 4.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5090) Phage_holin_5_2 PF16079.5 KFP05584.1 - 3.5 8.0 8.5 2.9 8.3 0.6 2.2 1 1 1 2 2 2 0 Phage holin family Hol44, in holin superfamily V Mad3_BUB1_I PF08311.12 KFP05585.1 - 3.8e-34 117.3 0.0 9.1e-34 116.1 0.0 1.7 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 KFP05585.1 - 5.1e-17 62.1 0.0 8.6e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP05585.1 - 1.4e-07 31.1 0.0 2.1e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 KFP05585.1 - 0.0092 16.1 0.1 0.03 14.4 0.0 1.9 2 0 0 2 2 2 1 Putative Mad3/BUB1 like region 1 protein Pkinase_fungal PF17667.1 KFP05585.1 - 0.079 11.7 0.9 0.16 10.8 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Cyclin_N2 PF16500.5 KFP05585.1 - 0.19 12.4 2.3 0.91 10.3 0.1 2.9 3 0 0 3 3 3 0 N-terminal region of cyclin_N Pox_ser-thr_kin PF05445.11 KFP05585.1 - 0.26 10.2 1.4 0.39 9.6 1.4 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MscS_TM PF12794.7 KFP05585.1 - 6 5.6 5.6 9.3 5.0 5.6 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Pkinase_Tyr PF07714.17 KFP05586.1 - 2e-90 302.6 0.0 2.7e-90 302.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP05586.1 - 3.5e-37 128.2 0.0 5.3e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Ig_2 PF13895.6 KFP05586.1 - 3.7e-15 56.0 0.0 3.4e-07 30.5 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain fn3 PF00041.21 KFP05586.1 - 7.6e-15 55.0 0.0 1.7e-06 28.3 0.2 3.1 3 0 0 3 3 3 2 Fibronectin type III domain Ig_3 PF13927.6 KFP05586.1 - 1.5e-14 54.3 0.8 1.1e-07 32.3 0.1 3.0 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFP05586.1 - 7.2e-11 42.1 0.0 4.8e-05 23.5 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP05586.1 - 8.3e-11 41.8 0.0 0.00014 21.9 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 KFP05586.1 - 0.0068 16.6 0.2 7.6 6.8 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP05586.1 - 0.033 14.3 0.0 2.6 8.1 0.0 2.7 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain zf_CCCH_4 PF18345.1 KFP05587.1 - 3.4e-14 52.3 29.4 1.8e-07 31.0 2.8 3.6 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 KFP05587.1 - 3e-13 49.2 20.6 0.00023 20.9 4.9 3.5 3 0 0 3 3 3 3 CCCH-type zinc finger zf-CCCH PF00642.24 KFP05587.1 - 9.1e-11 41.4 23.0 4.1e-05 23.4 1.7 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KFP05587.1 - 1.1e-06 28.9 21.9 0.021 15.3 1.3 3.6 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KFP05587.1 - 4.9e-05 23.5 16.0 0.00098 19.3 8.6 2.6 1 1 1 2 2 2 2 Zinc-finger containing family Torus PF16131.5 KFP05587.1 - 0.00044 20.9 11.7 0.0021 18.7 1.2 5.0 3 1 2 5 5 5 3 Torus domain SNAP PF14938.6 KFP05588.1 - 9.1e-98 327.1 20.3 1e-97 327.0 20.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KFP05588.1 - 8.8e-08 32.3 14.2 0.002 18.4 4.8 3.8 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFP05588.1 - 7.1e-05 23.4 4.8 0.0034 18.0 0.3 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFP05588.1 - 0.0009 19.7 9.6 4.7 8.1 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFP05588.1 - 0.0011 18.8 10.3 0.48 10.6 0.0 5.7 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFP05588.1 - 0.0019 18.2 16.0 1.7 9.0 0.1 5.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFP05588.1 - 0.0077 17.0 6.0 30 5.8 0.0 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFP05588.1 - 0.064 12.9 11.8 4.3 7.1 0.8 5.1 4 1 1 5 5 5 0 TPR repeat NSF PF02071.20 KFP05588.1 - 0.099 13.4 35.6 0.52 11.3 2.7 8.2 8 0 0 8 8 7 0 Aromatic-di-Alanine (AdAR) repeat TPR_10 PF13374.6 KFP05588.1 - 0.15 11.9 6.5 2.4 8.1 0.0 4.4 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFP05588.1 - 0.41 11.2 8.5 0.9 10.1 2.3 3.5 2 2 2 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.12 KFP05588.1 - 0.64 10.8 8.2 2.4 8.9 0.3 4.2 4 0 0 4 4 4 0 Sel1 repeat TPR_8 PF13181.6 KFP05588.1 - 2.5 8.6 21.9 3.4 8.1 0.5 6.5 6 2 1 7 7 7 0 Tetratricopeptide repeat zf-H2C2_2 PF13465.6 KFP05589.1 - 1.8e-72 236.8 84.6 6.2e-10 39.0 0.5 12.2 12 0 0 12 12 12 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFP05589.1 - 5.1e-51 168.4 97.1 2.1e-06 27.8 0.7 12.2 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP05589.1 - 1.6e-40 134.3 93.8 0.00019 22.0 0.9 12.1 12 0 0 12 12 12 12 C2H2-type zinc finger zf-met PF12874.7 KFP05589.1 - 4.2e-18 65.1 67.8 0.00072 19.9 0.3 12.0 12 0 0 12 12 12 8 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFP05589.1 - 3.2e-16 58.8 72.0 0.00041 20.1 0.5 12.3 12 1 0 12 12 12 7 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFP05589.1 - 7.3e-16 58.0 52.5 0.051 13.9 0.4 11.9 12 0 0 12 12 12 8 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP05589.1 - 3.9e-14 52.2 97.0 0.0068 16.4 3.0 12.7 12 1 0 12 12 12 7 C2H2-type zinc finger zf_UBZ PF18439.1 KFP05589.1 - 1e-07 31.4 51.6 0.58 9.8 0.1 11.9 12 0 0 12 12 12 5 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFP05589.1 - 2.7e-07 30.6 63.7 0.058 13.5 4.1 9.1 6 3 2 9 9 9 7 Zinc ribbon domain BolA PF01722.18 KFP05589.1 - 4.4e-06 26.9 17.2 0.011 16.0 1.6 6.3 3 2 4 7 7 6 2 BolA-like protein zf-C2HC_2 PF13913.6 KFP05589.1 - 7.1e-05 22.6 36.6 1.7 8.7 0.2 8.9 8 0 0 8 8 8 4 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.5 KFP05589.1 - 0.0004 20.6 43.7 0.3 11.4 6.0 5.6 1 1 4 5 5 5 4 C2H2-type zinc ribbon zinc_ribbon_15 PF17032.5 KFP05589.1 - 0.0026 18.5 48.8 2.5 8.9 3.4 6.4 2 2 6 8 8 8 2 zinc-ribbon family Ta0938 PF11494.8 KFP05589.1 - 0.0026 18.0 25.7 1.1 9.5 0.7 6.4 2 2 5 7 7 7 3 Ta0938 DUF3268 PF11672.8 KFP05589.1 - 0.012 16.0 44.0 0.25 11.7 0.4 6.5 3 2 3 8 8 8 0 zinc-finger-containing domain zf-C2H2_3rep PF18868.1 KFP05589.1 - 0.03 15.0 49.2 36 5.0 0.3 9.1 1 1 5 7 7 6 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 KFP05589.1 - 0.051 13.3 0.1 0.051 13.3 0.1 13.0 13 3 0 13 13 11 0 C2H2-type zinc-finger domain HypA PF01155.19 KFP05589.1 - 0.24 11.4 50.9 0.43 10.6 1.6 6.9 1 1 5 7 7 7 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA IBD PF10416.9 KFP05589.1 - 1 9.4 5.9 19 5.3 0.1 4.1 3 1 1 5 5 5 0 Transcription-initiator DNA-binding domain IBD zf-trcl PF13451.6 KFP05589.1 - 1 9.3 57.9 6 6.8 0.2 11.7 12 0 0 12 12 12 0 Probable zinc-ribbon domain ADK_lid PF05191.14 KFP05589.1 - 1.3 9.1 40.7 3.6 7.6 0.3 8.3 4 1 3 7 7 7 0 Adenylate kinase, active site lid 7tm_1 PF00001.21 KFP05590.1 - 6.1e-63 212.6 11.0 7e-63 212.4 11.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP05590.1 - 5.6e-15 55.4 2.9 6.5e-15 55.2 2.9 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP05590.1 - 2.8e-09 37.0 2.1 2.8e-09 37.0 2.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 KFP05590.1 - 0.00045 19.6 6.3 0.0049 16.2 0.1 2.5 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 KFP05590.1 - 0.00078 18.9 2.0 0.0016 17.9 2.0 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFP05590.1 - 0.0027 17.5 8.4 0.0084 15.9 8.4 1.8 1 1 0 1 1 1 1 Olfactory receptor Forkhead PF00250.18 KFP05591.1 - 2.1e-38 130.4 0.2 3.7e-38 129.7 0.2 1.4 1 0 0 1 1 1 1 Forkhead domain HNF_C PF09354.10 KFP05591.1 - 2.5e-26 92.5 11.2 2.5e-26 92.5 11.2 4.1 3 1 0 3 3 3 1 HNF3 C-terminal domain Forkhead_N PF08430.12 KFP05591.1 - 6.8e-25 88.3 45.3 6.8e-25 88.3 45.3 2.3 2 0 0 2 2 2 1 Forkhead N-terminal region Homeodomain PF00046.29 KFP05592.1 - 1.1e-14 54.0 0.0 2.4e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP05592.1 - 0.011 15.6 0.3 0.011 15.6 0.3 2.3 3 0 0 3 3 3 0 Homeobox KN domain XRN_M PF17846.1 KFP05594.1 - 2.4e-165 550.8 0.0 3.3e-165 550.3 0.0 1.2 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KFP05594.1 - 1.5e-103 345.5 0.0 2.7e-103 344.6 0.0 1.4 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Rap_GAP PF02145.15 KFP05595.1 - 4e-45 153.7 0.0 8.5e-45 152.6 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP DUF4821 PF16092.5 KFP05596.1 - 2.9e-100 335.3 4.3 3.3e-91 305.6 0.3 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4821) Pyr_redox_2 PF07992.14 KFP05596.1 - 5.3e-05 22.6 0.0 0.0004 19.7 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase CRAL_TRIO_2 PF13716.6 KFP05596.1 - 0.29 11.3 1.7 0.32 11.1 0.3 1.8 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain Na_Ca_ex PF01699.24 KFP05597.1 - 2e-58 196.7 40.4 3.9e-30 104.8 14.7 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein SPC25 PF06703.11 KFP05597.1 - 0.0041 16.9 2.4 0.029 14.2 0.1 2.6 2 0 0 2 2 2 1 Microsomal signal peptidase 25 kDa subunit (SPC25) BUD22 PF09073.10 KFP05597.1 - 0.0086 15.5 1.7 0.011 15.1 1.7 1.1 1 0 0 1 1 1 1 BUD22 CENP-B_dimeris PF09026.10 KFP05597.1 - 0.014 15.8 9.6 0.032 14.6 9.6 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RXT2_N PF08595.11 KFP05597.1 - 0.044 13.8 3.4 0.074 13.1 3.4 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF3449 PF11931.8 KFP05597.1 - 0.087 12.6 1.7 0.15 11.8 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) RNA_pol_3_Rpc31 PF11705.8 KFP05597.1 - 0.09 13.0 8.7 0.13 12.5 8.7 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 KFP05597.1 - 0.1 11.9 8.6 0.15 11.3 8.6 1.2 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 KFP05597.1 - 0.12 12.0 6.1 0.18 11.4 6.1 1.2 1 0 0 1 1 1 0 PPP4R2 RNA_pol_Rpc4 PF05132.14 KFP05597.1 - 0.13 12.7 0.8 0.19 12.1 0.8 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Cwf_Cwc_15 PF04889.12 KFP05597.1 - 0.19 11.4 8.6 0.28 10.9 8.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Astro_capsid_p PF12226.8 KFP05597.1 - 0.71 9.0 6.0 1.1 8.3 6.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Ribosomal_60s PF00428.19 KFP05597.1 - 1.7 9.3 7.1 3.6 8.2 7.1 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein p53-inducible11 PF14936.6 KFP05597.1 - 1.7 8.6 7.3 0.49 10.4 3.5 1.9 2 0 0 2 2 2 0 Tumour protein p53-inducible protein 11 WRNPLPNID PF15017.6 KFP05597.1 - 3.2 8.7 12.3 6.4 7.7 12.3 1.5 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box Myc_N PF01056.18 KFP05597.1 - 3.5 7.4 5.6 5.6 6.8 5.6 1.3 1 0 0 1 1 1 0 Myc amino-terminal region FAM176 PF14851.6 KFP05597.1 - 6.2 6.5 7.6 28 4.3 7.5 2.0 2 0 0 2 2 2 0 FAM176 family Pox_Ag35 PF03286.14 KFP05597.1 - 8.8 6.1 7.7 15 5.4 7.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TRAP_alpha PF03896.16 KFP05597.1 - 9.6 5.3 7.3 4.6 6.3 5.0 1.5 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit VPS9 PF02204.18 KFP05598.1 - 7.3e-23 80.8 0.2 1.6e-22 79.7 0.2 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain RA PF00788.23 KFP05598.1 - 1.8e-12 47.7 0.1 4.4e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain FERM_f0 PF16511.5 KFP05598.1 - 0.0077 16.5 0.1 0.064 13.6 0.0 2.4 3 0 0 3 3 3 1 N-terminal or F0 domain of Talin-head FERM SH2 PF00017.24 KFP05598.1 - 0.0096 16.0 0.0 0.041 14.0 0.0 2.1 2 0 0 2 2 2 1 SH2 domain VRP3 PF03536.15 KFP05598.1 - 0.075 12.5 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Salmonella virulence-associated 28kDa protein RelB PF04221.12 KFP05598.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 RelB antitoxin Acetyltransf_1 PF00583.25 KFP05599.1 - 8e-12 45.4 0.1 1.1e-11 44.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFP05599.1 - 3.9e-10 39.7 0.0 5.3e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFP05599.1 - 1.7e-08 34.3 0.1 2.7e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KFP05599.1 - 1.8e-08 34.7 0.0 2.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFP05599.1 - 0.002 18.2 0.0 0.0034 17.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Peptidase_C2 PF00648.21 KFP05600.1 - 2.2e-126 420.9 0.0 2.8e-126 420.5 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KFP05600.1 - 1.5e-44 151.6 0.0 2.7e-44 150.9 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_1 PF00036.32 KFP05600.1 - 4e-09 35.4 0.3 0.0028 17.1 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KFP05600.1 - 1.1e-07 31.6 2.3 2.7e-05 23.9 0.1 3.6 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP05600.1 - 2.2e-07 30.3 0.0 0.002 17.9 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KFP05600.1 - 7e-05 23.2 0.3 0.74 10.3 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP05600.1 - 0.0073 15.8 0.1 1.2 8.7 0.0 2.7 2 0 0 2 2 2 1 EF hand RVT_1 PF00078.27 KFP05603.1 - 3.7e-30 105.1 0.0 4.9e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 KFP05603.1 - 2.3e-11 43.4 0.4 5.2e-11 42.2 0.4 1.7 1 0 0 1 1 1 1 Reverse transcriptase thumb domain RVT_1 PF00078.27 KFP05604.1 - 3.8e-13 49.5 0.0 6e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PBECR3 PF18812.1 KFP05604.1 - 0.052 13.5 0.2 0.18 11.7 0.1 1.9 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 NAC PF01849.18 KFP05605.1 - 3.6e-26 90.9 0.2 5.6e-26 90.3 0.2 1.3 1 0 0 1 1 1 1 NAC domain LolA PF03548.15 KFP05605.1 - 0.079 12.7 0.6 0.11 12.2 0.6 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA Myco_19_kDa PF05481.12 KFP05605.1 - 0.083 13.2 0.1 0.12 12.7 0.1 1.2 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen dUTPase PF00692.19 KFP05606.1 - 2.7e-19 69.1 0.0 3.8e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 dUTPase RVP PF00077.20 KFP05606.1 - 0.017 15.5 0.1 0.041 14.2 0.1 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-Di19 PF05605.12 KFP05607.1 - 4.1e-05 23.8 0.1 8.9e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Di19_C PF14571.6 KFP05607.1 - 0.0011 19.4 2.1 0.0011 19.4 2.1 2.2 1 1 1 2 2 2 1 Stress-induced protein Di19, C-terminal PSD1 PF07587.11 KFP05607.1 - 0.15 11.5 11.0 0.22 11.0 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) TFIIA PF03153.13 KFP05607.1 - 0.28 11.2 9.0 0.32 11.0 9.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Kinesin PF00225.23 KFP05609.1 - 3.1e-60 203.9 0.0 5e-60 203.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFP05609.1 - 1.3e-16 60.9 0.0 4.2e-16 59.2 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding DUF1640 PF07798.11 KFP05609.1 - 1.3 9.0 5.6 2.9 7.9 5.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Asparaginase PF00710.20 KFP05610.1 - 2.3e-60 203.4 0.0 6.6e-59 198.7 0.0 2.3 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KFP05610.1 - 1.4e-27 96.2 0.0 3e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_4 PF13637.6 KFP05610.1 - 1.2e-16 60.8 0.2 1.4e-10 41.5 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP05610.1 - 4.2e-15 56.1 0.0 1.2e-13 51.4 0.0 2.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFP05610.1 - 2.7e-11 43.4 0.2 2e-06 28.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KFP05610.1 - 1.8e-10 40.9 0.0 2.7e-05 24.3 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP05610.1 - 2e-09 36.9 0.5 5e-05 23.4 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat HA2 PF04408.23 KFP05611.1 - 4.3e-14 52.7 0.0 1.1e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) TUDOR PF00567.24 KFP05611.1 - 4.5e-14 52.5 0.0 5.6e-13 49.0 0.0 2.5 2 0 0 2 2 2 1 Tudor domain Helicase_C PF00271.31 KFP05611.1 - 7e-13 48.9 0.0 2e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RD3 PF14473.6 KFP05612.1 - 3.3e-51 172.6 3.1 4.3e-51 172.2 3.1 1.1 1 0 0 1 1 1 1 RD3 protein Mit_proteolip PF08039.11 KFP05613.1 - 1.3e-08 35.1 1.5 1.3e-08 35.1 1.5 1.0 1 0 0 1 1 1 1 Mitochondrial proteolipid Ank_4 PF13637.6 KFP05614.1 - 7.8e-17 61.4 1.4 7.7e-12 45.5 0.6 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP05614.1 - 9e-17 61.5 0.0 1.8e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) SH3_1 PF00018.28 KFP05614.1 - 1.7e-13 50.0 1.4 3.3e-13 49.0 1.4 1.5 1 0 0 1 1 1 1 SH3 domain Ank PF00023.30 KFP05614.1 - 2.7e-13 49.7 1.4 2.2e-05 24.7 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFP05614.1 - 1.1e-12 46.9 0.7 2.4e-05 24.4 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat SH3_9 PF14604.6 KFP05614.1 - 2.5e-10 40.0 0.2 6.1e-10 38.8 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP05614.1 - 1.3e-09 37.6 0.0 2.7e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ank_5 PF13857.6 KFP05614.1 - 4.3e-08 33.3 0.2 1.4e-06 28.4 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) ZFYVE21_C PF16696.5 KFP05615.1 - 8.5e-54 180.7 0.0 1e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Zinc finger FYVE domain-containing protein 21 C-terminus FYVE PF01363.21 KFP05615.1 - 6.6e-12 45.4 23.5 1.3e-11 44.5 23.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KFP05615.1 - 8 6.7 19.9 38 4.5 18.8 2.4 1 1 1 2 2 2 0 FYVE-type zinc finger Rad51 PF08423.11 KFP05616.1 - 1.7e-36 125.8 0.0 2.4e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KFP05616.1 - 9.8e-07 28.5 0.0 1.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KFP05616.1 - 2.1e-05 24.2 0.1 0.022 14.2 0.0 2.2 1 1 1 2 2 2 2 recA bacterial DNA recombination protein ATPase PF06745.13 KFP05616.1 - 0.00047 19.6 0.0 0.00096 18.6 0.0 1.5 1 1 0 1 1 1 1 KaiC RNA_pol_A_CTD PF03118.15 KFP05616.1 - 0.027 14.2 0.1 0.067 13.0 0.1 1.6 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain TPR_12 PF13424.6 KFP05617.1 - 9.3e-69 227.7 23.2 1.4e-20 73.4 2.6 5.8 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 KFP05617.1 - 6.5e-63 207.0 14.6 1.2e-15 56.8 0.0 7.1 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 KFP05617.1 - 7.9e-33 110.1 16.8 4.2e-06 26.4 0.0 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 KFP05617.1 - 6.9e-29 98.5 31.3 1.4e-07 31.0 0.5 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KFP05617.1 - 7.6e-21 72.5 27.2 0.00035 20.4 2.7 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KFP05617.1 - 8.3e-14 50.6 27.0 0.0014 18.6 0.1 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFP05617.1 - 8.3e-14 52.0 9.1 0.00029 21.4 1.9 6.0 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP05617.1 - 1e-13 51.4 10.3 5.9e-13 48.9 2.6 3.5 3 1 0 3 3 3 1 MalT-like TPR region TPR_19 PF14559.6 KFP05617.1 - 6.8e-13 48.9 9.5 3e-05 24.5 0.1 4.8 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFP05617.1 - 8.8e-11 41.7 9.6 0.89 10.5 0.3 6.9 3 1 3 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFP05617.1 - 4.2e-10 39.3 10.1 0.027 14.8 0.2 6.8 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 KFP05617.1 - 1.9e-07 31.0 0.0 10 7.1 0.1 6.8 8 0 0 8 8 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP05617.1 - 4.1e-07 30.1 12.0 0.016 15.4 0.5 4.4 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 KFP05617.1 - 0.00016 21.7 2.2 0.13 12.6 0.0 4.5 6 0 0 6 6 4 1 PPR repeat JIP_LZII PF16471.5 KFP05617.1 - 0.0077 16.4 7.7 0.0077 16.4 7.7 2.8 1 1 0 2 2 2 1 JNK-interacting protein leucine zipper II TMF_TATA_bd PF12325.8 KFP05617.1 - 0.02 15.1 10.9 0.02 15.1 10.9 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding WbqC PF08889.11 KFP05617.1 - 0.083 12.8 8.5 10 6.0 0.0 4.2 4 1 1 5 5 4 0 WbqC-like protein family SHNi-TPR PF10516.9 KFP05617.1 - 0.11 11.9 4.7 9.5 5.8 0.1 4.6 5 0 0 5 5 5 0 SHNi-TPR GHL5 PF14872.6 KFP05617.1 - 0.13 10.3 5.7 0.2 9.7 5.7 1.2 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 PPR_2 PF13041.6 KFP05617.1 - 0.14 12.4 3.1 3.3 8.0 0.0 3.7 4 0 0 4 4 3 0 PPR repeat family CPDase PF07823.11 KFP05617.1 - 0.17 11.5 1.2 0.42 10.3 1.2 1.6 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein DUF627 PF04781.12 KFP05617.1 - 0.2 11.7 5.6 2.3 8.3 0.1 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF627) DUF4919 PF16266.5 KFP05617.1 - 0.21 11.5 0.1 0.21 11.5 0.1 3.4 3 2 1 4 4 4 0 Domain of unknown function (DUF4919) COG2 PF06148.11 KFP05617.1 - 0.42 10.7 9.0 0.24 11.5 5.8 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_11 PF13414.6 KFP05617.1 - 1.2 8.9 20.5 0.28 10.9 0.7 6.3 6 0 0 6 6 6 0 TPR repeat MIT PF04212.18 KFP05617.1 - 3.9 7.6 17.0 29 4.8 3.2 6.0 4 2 2 6 6 6 0 MIT (microtubule interacting and transport) domain HIP1_clath_bdg PF16515.5 KFP05617.1 - 6.5 7.4 22.0 20 5.9 9.1 3.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 YabA PF06156.13 KFP05617.1 - 9.5 6.9 19.2 0.11 13.1 5.3 3.7 3 0 0 3 3 3 0 Initiation control protein YabA DUF2315 PF10231.9 KFP05618.1 - 3.3e-47 159.6 0.7 4.1e-47 159.3 0.7 1.1 1 0 0 1 1 1 1 Apoptogenic protein 1 GCD14 PF08704.10 KFP05619.1 - 1.8e-108 361.9 0.0 2.1e-108 361.6 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 KFP05619.1 - 2.1e-07 30.8 0.0 3.2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFP05619.1 - 3e-05 23.9 0.0 4.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KFP05619.1 - 0.002 18.8 0.0 0.0038 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KFP05619.1 - 0.0065 17.5 0.0 0.011 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 KFP05619.1 - 0.034 13.8 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_12 PF08242.12 KFP05619.1 - 0.04 14.7 0.0 0.082 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain GCD14_N PF14801.6 KFP05619.1 - 0.049 13.5 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term CMAS PF02353.20 KFP05619.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase ATP-gua_Ptrans PF00217.19 KFP05620.1 - 2.9e-82 275.3 0.0 3.8e-82 274.9 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 KFP05620.1 - 2.3e-34 117.6 0.1 7.9e-16 58.2 0.0 2.4 2 0 0 2 2 2 2 ATP:guanido phosphotransferase, N-terminal domain Pkinase PF00069.25 KFP05621.1 - 1.6e-75 253.9 0.0 2.5e-75 253.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP05621.1 - 2.6e-45 154.8 0.0 5e-45 153.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KFP05621.1 - 6.7e-21 73.8 0.1 1.7e-20 72.5 0.0 1.8 2 0 0 2 2 2 1 Kinase associated domain 1 Kinase-like PF14531.6 KFP05621.1 - 1.1e-07 31.5 0.0 1.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like UBA PF00627.31 KFP05621.1 - 1.2e-05 25.1 0.0 2.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RIO1 PF01163.22 KFP05621.1 - 0.00028 20.5 0.2 0.0006 19.5 0.2 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KFP05621.1 - 0.0011 18.3 0.2 0.0021 17.5 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UBA_2 PF08587.11 KFP05621.1 - 0.0066 16.5 0.3 0.016 15.3 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Haspin_kinase PF12330.8 KFP05621.1 - 0.052 12.5 0.1 0.052 12.5 0.1 1.6 2 0 0 2 2 2 0 Haspin like kinase domain eIF-5_eIF-2B PF01873.17 KFP05622.1 - 2.2e-42 143.6 0.7 1.2e-41 141.2 0.1 2.3 3 0 0 3 3 3 1 Domain found in IF2B/IF5 W2 PF02020.18 KFP05622.1 - 5.8e-21 74.4 3.6 5.8e-21 74.4 3.6 2.7 2 1 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon PGA2 PF07543.12 KFP05622.1 - 5.6 6.9 10.1 13 5.8 0.2 2.6 2 0 0 2 2 2 0 Protein trafficking PGA2 Luciferase_N PF05295.11 KFP05623.1 - 0.098 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain Mating_N PF12731.7 KFP05623.1 - 0.14 12.2 2.3 0.35 11.0 2.3 1.6 1 0 0 1 1 1 0 Mating-type protein beta 1 Sec6 PF06046.13 KFP05624.1 - 1.3e-73 248.3 11.2 1.5e-73 248.1 11.2 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec6 HD_2 PF12917.7 KFP05624.1 - 0.025 14.3 2.2 5.1 6.8 0.4 2.8 2 1 0 2 2 2 0 HD containing hydrolase-like enzyme MDD_C PF18376.1 KFP05624.1 - 0.036 13.8 0.7 3.8 7.2 0.0 3.1 3 2 0 3 3 3 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain COPI_C PF06957.11 KFP05624.1 - 0.043 12.6 1.0 0.077 11.7 0.4 1.5 1 1 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus Sec6 PF06046.13 KFP05625.1 - 4.1e-64 217.0 6.6 5.7e-64 216.5 6.6 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 DciA PF05258.12 KFP05625.1 - 0.097 13.1 0.1 1.7 9.1 0.0 2.7 2 0 0 2 2 2 0 Dna[CI] antecedent, DciA RGS-like PF09128.11 KFP05625.1 - 0.098 12.4 2.7 0.17 11.6 1.2 2.0 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain DUF5071 PF16804.5 KFP05625.1 - 0.42 10.9 4.2 0.31 11.3 0.3 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF5071) Lbh PF15317.6 KFP05627.1 - 5.7e-25 88.1 1.5 6.7e-25 87.9 1.5 1.1 1 0 0 1 1 1 1 Cardiac transcription factor regulator, Developmental protein CNH PF00780.22 KFP05628.1 - 5.9e-72 242.6 0.1 1.1e-71 241.7 0.1 1.5 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.25 KFP05628.1 - 8.3e-56 189.3 0.0 8.3e-56 189.3 0.0 2.6 3 0 0 3 3 3 1 Protein kinase domain KELK PF15796.5 KFP05628.1 - 1.5e-31 108.7 21.0 1.5e-31 108.7 21.0 7.2 6 2 2 8 8 5 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pkinase_Tyr PF07714.17 KFP05628.1 - 4.3e-29 101.6 0.0 4.3e-29 101.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase DMPK_coil PF08826.10 KFP05628.1 - 9.4e-26 89.7 11.6 9.4e-26 89.7 11.6 9.3 7 2 3 10 10 9 1 DMPK coiled coil domain like C1_1 PF00130.22 KFP05628.1 - 4.6e-10 39.2 5.9 1e-09 38.1 5.9 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 KFP05628.1 - 4.8e-07 29.4 0.0 1.6e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 KFP05628.1 - 0.00049 20.8 1.1 0.0011 19.6 1.1 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain PBD PF00786.28 KFP05628.1 - 0.00087 19.6 0.2 0.0039 17.5 0.2 2.2 1 0 0 1 1 1 1 P21-Rho-binding domain Myosin_tail_1 PF01576.19 KFP05628.1 - 0.0014 16.6 105.9 0.0046 14.9 79.6 3.0 1 1 2 3 3 3 2 Myosin tail PH PF00169.29 KFP05628.1 - 0.014 15.9 0.0 0.11 13.0 0.0 2.6 2 0 0 2 2 2 0 PH domain C1_2 PF03107.16 KFP05628.1 - 0.016 15.5 5.0 0.043 14.1 5.0 1.7 1 0 0 1 1 1 0 C1 domain Filament PF00038.21 KFP05628.1 - 0.028 14.0 87.8 0.021 14.4 2.3 5.2 1 1 2 5 5 5 0 Intermediate filament protein AATF-Che1 PF13339.6 KFP05628.1 - 0.05 14.3 0.5 0.05 14.3 0.5 5.6 3 1 2 5 5 4 0 Apoptosis antagonizing transcription factor DUF3450 PF11932.8 KFP05628.1 - 0.16 11.3 69.6 0.088 12.1 6.2 5.6 2 1 2 5 5 5 0 Protein of unknown function (DUF3450) Baculo_PEP_C PF04513.12 KFP05628.1 - 1.5 8.8 20.2 0.79 9.8 0.6 4.4 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_A3 PF02160.15 KFP05628.1 - 9.8 5.6 13.8 0.18 11.3 5.2 2.5 2 0 0 2 2 2 0 Cauliflower mosaic virus peptidase (A3) Amnionless PF14828.6 KFP05629.1 - 2.3e-136 455.2 0.0 2.6e-136 455.0 0.0 1.0 1 0 0 1 1 1 1 Amnionless zf-TRAF PF02176.18 KFP05630.1 - 1.9e-25 89.3 24.4 2.4e-16 60.1 7.9 4.4 1 1 3 4 4 3 2 TRAF-type zinc finger Sina PF03145.16 KFP05630.1 - 5.4e-05 23.2 24.8 0.004 17.1 8.0 3.5 1 1 2 3 3 3 2 Seven in absentia protein family MPS2 PF17060.5 KFP05630.1 - 0.00073 18.9 6.3 0.0011 18.3 6.3 1.2 1 0 0 1 1 1 1 Monopolar spindle protein 2 zf-C3HC4 PF00097.25 KFP05630.1 - 0.0016 18.3 14.6 0.0016 18.3 14.6 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Cast PF10174.9 KFP05630.1 - 0.0027 16.1 11.6 0.0035 15.6 10.7 1.6 1 1 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone ATG16 PF08614.11 KFP05630.1 - 0.0028 17.9 6.3 0.0028 17.9 6.3 2.2 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) FliJ PF02050.16 KFP05630.1 - 0.0093 16.2 9.3 0.01 16.0 8.3 1.6 1 1 0 1 1 1 1 Flagellar FliJ protein zf-C3HC4_2 PF13923.6 KFP05630.1 - 0.012 15.4 13.3 0.012 15.4 13.3 2.9 2 1 1 3 3 1 0 Zinc finger, C3HC4 type (RING finger) Spc7 PF08317.11 KFP05630.1 - 0.027 13.3 14.7 0.042 12.7 14.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Spc29 PF17082.5 KFP05630.1 - 0.082 12.7 6.3 0.04 13.8 3.7 1.7 1 1 0 1 1 1 0 Spindle Pole Component 29 Tropomyosin_1 PF12718.7 KFP05630.1 - 0.091 12.9 15.5 0.41 10.8 15.5 2.3 1 1 0 1 1 1 0 Tropomyosin like SPATA24 PF15175.6 KFP05630.1 - 0.093 12.6 13.4 0.091 12.6 8.0 2.3 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 KxDL PF10241.9 KFP05630.1 - 0.12 12.7 5.7 0.1 12.9 3.8 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein T3SSipB PF16535.5 KFP05630.1 - 0.13 12.8 3.8 0.11 13.0 2.2 1.6 1 1 0 1 1 1 0 Type III cell invasion protein SipB DUF1664 PF07889.12 KFP05630.1 - 0.13 12.3 5.4 0.24 11.4 4.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 KFP05630.1 - 0.14 12.4 8.3 0.21 11.9 3.9 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-RING_6 PF14835.6 KFP05630.1 - 0.15 12.0 5.8 0.25 11.3 4.2 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein ADIP PF11559.8 KFP05630.1 - 0.17 12.0 15.8 0.077 13.1 10.8 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Exonuc_VII_L PF02601.15 KFP05630.1 - 0.75 9.3 8.7 1.1 8.7 8.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 KFP05630.1 - 1.4 8.1 6.8 2.4 7.3 6.8 1.5 1 0 0 1 1 1 0 TMPIT-like protein LMBR1 PF04791.16 KFP05630.1 - 2.2 7.1 4.9 3.1 6.6 4.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Myb_DNA-binding PF00249.31 KFP05631.1 - 6.2e-17 61.5 0.8 2.3e-09 37.3 0.0 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFP05631.1 - 1e-06 28.5 9.5 0.00094 19.0 0.1 3.2 2 1 1 3 3 3 2 Myb DNA-binding like ELM2 PF01448.24 KFP05631.1 - 7.6e-05 23.4 0.0 7.6e-05 23.4 0.0 2.9 2 1 0 2 2 2 1 ELM2 domain Myb_DNA-bind_6 PF13921.6 KFP05631.1 - 0.00019 21.6 4.1 0.12 12.6 0.1 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Arnt_C PF18583.1 KFP05631.1 - 0.0074 15.9 0.3 4 7.1 0.1 2.7 2 0 0 2 2 2 2 Aminoarabinose transferase C-terminal domain Homeobox_KN PF05920.11 KFP05631.1 - 0.063 13.2 0.1 0.2 11.6 0.1 1.9 1 0 0 1 1 1 0 Homeobox KN domain RR_TM4-6 PF06459.12 KFP05631.1 - 2 8.2 11.8 0.24 11.2 6.5 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Ank_5 PF13857.6 KFP05632.1 - 1.4e-07 31.6 0.4 6.7e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP05632.1 - 6.7e-05 23.4 0.0 0.00024 21.6 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFP05632.1 - 0.00011 22.5 1.4 0.00051 20.4 0.1 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KFP05632.1 - 0.00021 21.8 0.7 0.0017 18.9 0.0 2.5 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP05632.1 - 0.0028 18.0 1.4 0.054 14.1 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeat Hyd_WA PF06462.12 KFP05633.1 - 8.9e-38 128.0 18.5 1e-06 28.6 0.9 8.5 8 0 0 8 8 8 6 Propeller ANAPC4_WD40 PF12894.7 KFP05633.1 - 0.00071 19.8 0.0 0.0028 17.9 0.0 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFP05633.1 - 0.0098 15.2 0.0 0.046 13.0 0.0 2.1 2 0 0 2 2 2 1 WD40-like domain WD40 PF00400.32 KFP05633.1 - 0.01 16.7 0.1 0.27 12.2 0.0 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat BBP1_N PF15271.6 KFP05633.1 - 0.025 15.4 1.5 0.025 15.4 1.5 1.7 2 0 0 2 2 2 0 Spindle pole body component BBP1, Mps2-binding protein DTHCT PF08070.11 KFP05633.1 - 5.8 7.7 9.1 3.8 8.3 3.7 2.6 2 0 0 2 2 2 0 DTHCT (NUC029) region CK2S PF15011.6 KFP05634.1 - 0.027 14.4 3.1 0.053 13.4 3.1 1.6 1 1 0 1 1 1 0 Casein Kinase 2 substrate DUF4764 PF15961.5 KFP05635.1 - 1.8e-19 70.0 3.5 2e-19 69.9 3.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4764) DUF4764 PF15961.5 KFP05636.1 - 2.1e-126 423.6 16.3 1.3e-82 278.8 7.6 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4764) zf-C2H2 PF00096.26 KFP05636.1 - 0.013 15.9 0.1 0.031 14.7 0.1 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Pkinase PF00069.25 KFP05637.1 - 7.7e-70 235.3 0.0 9.6e-70 234.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP05637.1 - 1.1e-31 110.1 0.0 1.5e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP05637.1 - 7e-06 25.6 0.0 1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFP05637.1 - 0.0041 16.5 0.1 0.01 15.2 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KFP05637.1 - 0.02 14.5 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 WD40 PF00400.32 KFP05638.1 - 4.2e-12 46.4 3.7 0.0002 22.1 0.2 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP05638.1 - 2e-08 34.4 0.0 0.49 10.7 0.0 4.2 1 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KFP05638.1 - 0.00043 20.1 0.0 0.84 9.6 0.0 2.5 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KFP05638.1 - 0.019 13.9 0.0 0.064 12.2 0.0 1.8 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFP05638.1 - 0.036 13.9 0.0 0.21 11.5 0.0 2.0 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A HSP90 PF00183.18 KFP05639.1 - 2.5e-234 778.9 32.3 3.2e-234 778.6 32.3 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KFP05639.1 - 1e-13 51.8 0.1 2.4e-13 50.6 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFP05639.1 - 9.5e-12 44.9 0.1 2.9e-11 43.3 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 KFP05639.1 - 0.11 12.5 1.3 0.35 10.9 0.2 2.2 2 0 0 2 2 2 0 Tumour suppressor protein Zip PF02535.22 KFP05639.1 - 0.27 10.4 0.4 0.59 9.3 0.4 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 KFP05639.1 - 2.5 6.3 14.0 4.9 5.3 14.0 1.4 1 0 0 1 1 1 0 CDC45-like protein DHC_N1 PF08385.12 KFP05641.1 - 4.4e-136 454.8 11.8 4.4e-136 454.8 11.8 4.9 5 1 1 6 6 5 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 KFP05641.1 - 1.2e-129 431.9 4.7 1.8e-126 421.5 0.0 4.6 4 1 0 4 4 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KFP05641.1 - 2.2e-102 343.1 14.4 2.2e-102 343.1 14.4 5.5 6 1 0 6 6 4 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KFP05641.1 - 3.8e-72 242.0 0.0 3.8e-72 242.0 0.0 3.7 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 KFP05641.1 - 6.9e-70 235.3 0.0 6.4e-69 232.2 0.0 2.9 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KFP05641.1 - 7e-53 179.8 0.7 7e-53 179.8 0.7 2.6 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 KFP05641.1 - 8.6e-46 155.7 0.0 1.1e-38 132.6 0.0 5.4 6 0 0 6 6 6 2 P-loop containing dynein motor region MT PF12777.7 KFP05641.1 - 2.8e-42 145.0 14.5 2.8e-42 145.0 14.5 2.0 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 KFP05641.1 - 5.6e-42 143.3 0.0 1.5e-41 142.0 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KFP05641.1 - 4e-31 107.6 0.0 8.2e-30 103.3 0.0 3.4 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KFP05641.1 - 3.4e-30 104.8 0.0 2.9e-12 46.8 0.0 5.9 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KFP05641.1 - 4e-18 65.7 0.0 1.6e-17 63.8 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 KFP05641.1 - 4.7e-13 49.6 10.0 0.014 15.7 0.0 7.8 8 0 0 8 8 7 4 AAA domain AAA PF00004.29 KFP05641.1 - 1.2e-12 48.3 0.0 0.05 14.0 0.0 5.3 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KFP05641.1 - 2.5e-11 43.9 0.1 0.035 14.3 0.0 5.9 5 0 0 5 5 4 3 AAA domain AAA_16 PF13191.6 KFP05641.1 - 1.6e-10 41.6 0.0 2.3 8.6 0.0 7.2 6 0 0 6 6 6 3 AAA ATPase domain AAA_18 PF13238.6 KFP05641.1 - 4.4e-10 40.2 4.1 0.12 12.9 0.0 6.7 7 0 0 7 7 5 3 AAA domain Mg_chelatase PF01078.21 KFP05641.1 - 8e-07 28.6 0.5 0.14 11.6 0.0 3.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 KFP05641.1 - 2.6e-05 24.0 0.3 11 5.7 0.0 4.6 4 0 0 4 4 4 0 AAA domain IstB_IS21 PF01695.17 KFP05641.1 - 0.0001 22.1 0.3 0.12 12.1 0.0 4.4 4 0 0 4 4 4 1 IstB-like ATP binding protein ABC_tran PF00005.27 KFP05641.1 - 0.00016 22.2 3.3 4 8.0 0.0 5.3 4 0 0 4 4 3 2 ABC transporter T2SSE PF00437.20 KFP05641.1 - 0.00021 20.5 0.0 0.16 11.0 0.0 3.6 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_29 PF13555.6 KFP05641.1 - 0.00027 20.6 0.0 2.5 7.9 0.0 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_lid_1 PF17857.1 KFP05641.1 - 0.00086 19.5 0.0 0.00086 19.5 0.0 3.0 3 0 0 3 3 1 1 AAA+ lid domain AAA_19 PF13245.6 KFP05641.1 - 0.0012 19.1 2.2 0.24 11.7 0.0 4.8 5 0 0 5 5 4 1 AAA domain AAA_24 PF13479.6 KFP05641.1 - 0.0013 18.5 0.2 29 4.3 0.0 4.8 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.22 KFP05641.1 - 0.002 18.5 0.0 14 6.1 0.0 5.1 5 0 0 5 5 5 0 RNA helicase Rad17 PF03215.15 KFP05641.1 - 0.0023 17.9 1.4 29 4.5 0.0 4.9 5 0 0 5 5 4 0 Rad17 P-loop domain Phlebovirus_NSM PF07246.11 KFP05641.1 - 0.0027 17.2 2.1 0.0027 17.2 2.1 2.7 2 0 0 2 2 1 1 Phlebovirus nonstructural protein NS-M FtsK_SpoIIIE PF01580.18 KFP05641.1 - 0.0031 16.9 0.0 3.8 6.8 0.0 3.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_25 PF13481.6 KFP05641.1 - 0.018 14.7 0.1 0.47 10.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain ERM PF00769.19 KFP05641.1 - 0.023 14.5 41.7 0.0038 17.1 7.0 3.7 3 0 0 3 3 2 0 Ezrin/radixin/moesin family TsaE PF02367.17 KFP05641.1 - 0.19 11.7 1.3 12 5.9 0.0 3.9 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE B56 PF01603.20 KFP05642.1 - 1.6e-200 666.4 10.8 2.1e-200 666.0 10.8 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KFP05642.1 - 0.15 12.0 1.8 2.1 8.3 0.3 2.8 1 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal T4_deiodinase PF00837.17 KFP05643.1 - 9e-54 182.3 0.0 1e-53 182.1 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase DUF5039 PF16442.5 KFP05643.1 - 0.098 12.2 0.0 0.098 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5039) T4_deiodinase PF00837.17 KFP05644.1 - 4.3e-36 124.4 0.0 4.9e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase GTP_cyclohydro2 PF00925.20 KFP05644.1 - 0.23 11.1 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 GTP cyclohydrolase II EGF PF00008.27 KFP05646.1 - 4.6e-34 116.3 86.5 1.9e-09 37.7 10.3 6.7 6 0 0 6 6 6 6 EGF-like domain hEGF PF12661.7 KFP05646.1 - 6e-16 58.4 76.0 0.00016 22.2 5.8 7.6 6 0 0 6 6 6 6 Human growth factor-like EGF EGF_2 PF07974.13 KFP05646.1 - 4.1e-14 52.7 100.2 0.00036 20.8 9.2 6.3 6 0 0 6 6 6 6 EGF-like domain Laminin_EGF PF00053.24 KFP05646.1 - 0.05 13.8 71.3 0.19 11.9 8.1 6.5 3 2 3 6 6 6 0 Laminin EGF domain EGF_CA PF07645.15 KFP05646.1 - 4.2 7.7 81.9 0.26 11.5 9.6 6.7 4 1 2 6 6 6 0 Calcium-binding EGF domain Yae1_N PF09811.9 KFP05647.1 - 7.4e-13 48.0 48.2 1.8e+04 -13.2 48.2 4.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Ribosomal_S4e PF00900.20 KFP05648.1 - 1.9e-39 133.4 0.7 3.1e-39 132.7 0.7 1.4 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.12 KFP05648.1 - 1.4e-21 76.3 4.1 3e-21 75.2 4.1 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain 40S_S4_C PF16121.5 KFP05648.1 - 3.4e-08 33.0 0.5 6.3e-08 32.2 0.5 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 KFP05648.1 - 3.4e-06 26.7 0.0 6.3e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KFP05648.1 - 3.6e-06 26.7 0.2 1.8e-05 24.5 0.2 2.3 1 0 0 1 1 1 1 KOW motif Sipho_tail PF05709.11 KFP05648.1 - 0.046 13.1 0.1 0.059 12.8 0.1 1.2 1 0 0 1 1 1 0 Phage tail protein WND PF07861.11 KFP05648.1 - 0.17 11.3 0.7 0.23 10.9 0.7 1.2 1 0 0 1 1 1 0 WisP family N-Terminal Region Glyco_hydro_15 PF00723.21 KFP05649.1 - 2.5e-152 507.8 0.0 3.1e-152 507.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Lipase_C PF18067.1 KFP05649.1 - 0.07 13.7 0.0 5.9 7.5 0.0 2.5 2 0 0 2 2 2 0 Lipase C-terminal domain TGF_beta PF00019.20 KFP05650.1 - 4.8e-28 98.2 0.1 7.1e-28 97.6 0.1 1.2 1 0 0 1 1 1 1 Transforming growth factor beta like domain ASD2 PF08687.11 KFP05652.1 - 7.5e-57 193.1 6.4 8.3e-57 193.0 6.4 1.0 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 Amido_AtzD_TrzD PF09663.10 KFP05652.1 - 0.033 13.2 0.1 0.039 13.0 0.1 1.1 1 0 0 1 1 1 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) TetR_C_34 PF17929.1 KFP05652.1 - 0.07 13.2 0.2 0.47 10.6 0.1 1.9 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Cyclin_N PF00134.23 KFP05653.1 - 4.5e-06 26.4 0.0 7.5e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Gal_Lectin PF02140.18 KFP05654.1 - 7.5e-39 132.0 8.2 4.9e-20 71.7 1.4 2.3 2 0 0 2 2 2 2 Galactose binding lectin domain FAM176 PF14851.6 KFP05654.1 - 2.4e-09 37.0 0.0 4e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 FAM176 family DUF3395 PF11875.8 KFP05654.1 - 0.0032 17.4 0.0 4.6 7.1 0.0 3.2 2 2 0 2 2 2 2 Domain of unknown function (DUF3395) GST_C_2 PF13410.6 KFP05655.1 - 2.5e-06 27.4 0.0 4.1e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFP05655.1 - 3.9e-06 27.1 0.0 7.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFP05655.1 - 0.00087 19.7 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 KFP05655.1 - 0.0049 17.1 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_C PF00043.25 KFP05655.1 - 0.019 15.2 0.0 0.059 13.6 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF1533 PF07550.11 KFP05655.1 - 0.044 13.7 0.1 0.1 12.5 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1533) Amidase PF01425.21 KFP05657.1 - 1.5e-78 264.8 0.1 4.4e-78 263.3 0.1 1.7 1 1 0 1 1 1 1 Amidase TSC22 PF01166.18 KFP05658.1 - 3.4e-28 97.7 4.9 3.4e-28 97.7 4.9 1.8 2 0 0 2 2 2 1 TSC-22/dip/bun family YabA PF06156.13 KFP05658.1 - 0.00052 20.6 2.6 0.00052 20.6 2.6 1.7 2 0 0 2 2 2 1 Initiation control protein YabA DivIC PF04977.15 KFP05658.1 - 0.0014 18.3 3.5 0.0064 16.2 2.2 2.2 2 0 0 2 2 2 1 Septum formation initiator ZapB PF06005.12 KFP05658.1 - 0.0043 17.4 4.2 0.0043 17.4 4.2 1.7 2 0 0 2 2 2 1 Cell division protein ZapB TBK1_CCD1 PF18394.1 KFP05658.1 - 0.0052 16.4 2.7 0.041 13.4 1.2 2.0 1 1 1 2 2 2 1 TANK-binding kinase 1 coiled-coil domain 1 K-box PF01486.17 KFP05658.1 - 0.009 16.2 1.6 0.009 16.2 1.6 1.9 2 0 0 2 2 2 1 K-box region bZIP_2 PF07716.15 KFP05658.1 - 0.13 12.4 5.4 0.3 11.2 5.4 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Fzo_mitofusin PF04799.13 KFP05658.1 - 0.22 11.1 3.5 0.068 12.7 0.9 1.5 2 0 0 2 2 2 0 fzo-like conserved region CysA_C_terminal PF17850.1 KFP05659.1 - 0.2 12.3 7.0 4.5e+02 1.5 7.0 3.8 1 1 0 1 1 1 0 CysA C-terminal regulatory domain COS PF18568.1 KFP05660.1 - 2.4e-34 117.0 0.8 2.1e-33 114.0 1.1 2.3 2 0 0 2 2 2 1 TRIM C-terminal subgroup One Signature domain SPRY PF00622.28 KFP05660.1 - 5.1e-13 49.2 0.0 9e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 SPRY domain zf-B_box PF00643.24 KFP05660.1 - 5.8e-09 36.0 1.0 5.8e-09 36.0 1.0 4.5 6 0 0 6 6 5 2 B-box zinc finger zf-C3HC4_3 PF13920.6 KFP05660.1 - 2.7e-07 30.3 4.7 2.7e-07 30.3 4.7 4.0 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP05660.1 - 3.3e-07 30.2 8.3 3.3e-07 30.2 8.3 3.5 3 0 0 3 3 3 1 RING-type zinc-finger PRY PF13765.6 KFP05660.1 - 5.4e-07 29.1 0.0 1.8e-06 27.5 0.0 2.0 1 0 0 1 1 1 1 SPRY-associated domain fn3 PF00041.21 KFP05660.1 - 6.2e-07 29.7 0.2 1.3e-06 28.7 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III domain zf-C3HC4 PF00097.25 KFP05660.1 - 9e-07 28.7 8.9 9e-07 28.7 8.9 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP05660.1 - 4.2e-06 26.5 5.4 4.2e-06 26.5 5.4 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFP05660.1 - 6e-06 26.3 11.4 6e-06 26.3 11.4 4.1 5 0 0 5 5 5 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFP05660.1 - 3.2e-05 24.2 9.5 3.2e-05 24.2 9.5 3.5 4 0 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 KFP05660.1 - 0.00036 20.4 7.7 0.00036 20.4 7.7 3.7 4 0 0 4 4 4 1 zinc-RING finger domain CEBP_ZZ PF16366.5 KFP05660.1 - 0.024 14.9 2.8 0.024 14.9 2.8 2.9 3 0 0 3 3 3 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Pur_ac_phosph_N PF16656.5 KFP05660.1 - 0.037 14.6 0.1 0.088 13.4 0.1 1.7 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain FAD-oxidase_C PF02913.19 KFP05660.1 - 0.14 11.8 0.4 0.21 11.2 0.4 1.2 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain SNF2_N PF00176.23 KFP05661.1 - 1.4e-50 172.0 0.4 6.6e-49 166.5 0.1 2.3 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFP05661.1 - 2.3e-20 73.0 0.1 3e-19 69.4 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP05661.1 - 3e-13 50.1 0.0 4.2e-12 46.4 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 KFP05661.1 - 1.4e-05 24.1 0.0 2.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 SWI2_SNF2 PF18766.1 KFP05661.1 - 0.00011 22.0 0.1 0.00064 19.5 0.0 2.0 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DEAD PF00270.29 KFP05661.1 - 0.00069 19.4 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KFP05661.1 - 0.00095 18.4 0.0 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD_2 PF06733.15 KFP05661.1 - 0.06 13.0 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 DEAD_2 DUF2785 PF10978.8 KFP05661.1 - 0.13 12.0 0.1 0.31 10.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) OCRL_clath_bd PF16726.5 KFP05662.1 - 9.3e-32 109.3 0.4 2.2e-31 108.1 0.4 1.7 1 0 0 1 1 1 1 Inositol polyphosphate 5-phosphatase clathrin binding domain RhoGAP PF00620.27 KFP05662.1 - 1.3e-25 90.1 0.1 2.2e-25 89.2 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 KFP05662.1 - 1.5e-16 60.7 0.0 2.2e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family INPP5B_PH PF16776.5 KFP05662.1 - 0.038 13.7 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain Creatinase_N_2 PF16189.5 KFP05663.1 - 2e-39 135.3 0.0 5.8e-39 133.8 0.0 1.7 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Creatinase_N PF01321.18 KFP05663.1 - 9.1e-14 52.2 0.0 4.7e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KFP05664.1 - 3.3e-34 118.4 0.0 3.9e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KFP05664.1 - 1.1e-19 70.2 0.1 1.9e-19 69.5 0.1 1.4 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 SAM_1 PF00536.30 KFP05665.1 - 5.2e-09 36.4 0.2 7.8e-09 35.9 0.2 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP05665.1 - 1.1e-08 35.0 0.7 1.6e-08 34.5 0.7 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SLY PF12485.8 KFP05665.1 - 8.1e-07 29.9 0.3 1.7e-06 28.8 0.3 1.6 1 0 0 1 1 1 1 Lymphocyte signaling adaptor protein SH3_2 PF07653.17 KFP05665.1 - 3.2e-06 26.7 0.0 5.7e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP05665.1 - 0.0043 16.6 0.0 0.0082 15.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain ComC PF03047.14 KFP05665.1 - 0.26 11.1 0.5 0.59 10.0 0.5 1.6 1 0 0 1 1 1 0 COMC family DHHC PF01529.20 KFP05666.1 - 2.4e-36 124.8 11.2 2.4e-36 124.8 11.2 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase UPF0182 PF03699.13 KFP05666.1 - 0.022 12.9 0.1 0.022 12.9 0.1 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0182) Utp14 PF04615.13 KFP05667.1 - 6.3e-144 481.4 33.1 1e-81 275.7 24.9 2.0 2 0 0 2 2 2 2 Utp14 protein PUFD PF16553.5 KFP05668.1 - 7.6e-51 171.1 0.3 1.5e-50 170.1 0.3 1.5 1 0 0 1 1 1 1 BCORL-PCGF1-binding domain Ank_2 PF12796.7 KFP05668.1 - 1.3e-12 48.1 0.1 4.2e-08 33.7 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP05668.1 - 4.4e-11 43.1 0.7 6.9e-07 29.7 0.3 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP05668.1 - 9e-11 41.0 0.4 2.9e-05 24.1 0.3 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KFP05668.1 - 2.7e-08 33.9 0.8 8.3e-05 22.9 0.2 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KFP05668.1 - 4e-07 30.2 2.6 0.00017 21.8 0.4 3.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) AIF_C PF14721.6 KFP05669.1 - 8.9e-59 197.5 0.0 1.3e-58 197.0 0.0 1.2 1 0 0 1 1 1 1 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox_2 PF07992.14 KFP05669.1 - 2.4e-44 151.8 0.0 3.8e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFP05669.1 - 2.7e-14 53.5 0.2 1e-12 48.4 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase AIF-MLS PF14962.6 KFP05669.1 - 5e-08 33.1 0.1 5e-08 33.1 0.1 1.8 2 0 0 2 2 2 1 Mitochondria Localisation Sequence Pyr_redox_3 PF13738.6 KFP05669.1 - 1.6e-06 27.6 0.0 1.4e-05 24.5 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFP05669.1 - 4.9e-05 23.4 3.8 0.17 11.9 0.1 4.1 3 1 1 4 4 4 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KFP05669.1 - 0.00026 20.4 1.4 0.0083 15.5 0.1 2.2 1 1 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KFP05669.1 - 0.0034 16.2 0.6 0.64 8.7 0.0 3.0 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.6 KFP05669.1 - 0.0077 16.4 1.3 2.8 8.2 0.1 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KFP05669.1 - 0.018 14.2 0.0 0.11 11.6 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) PYNP_C PF07831.13 KFP05669.1 - 0.057 13.1 0.1 0.37 10.5 0.0 2.1 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain FAD_oxidored PF12831.7 KFP05669.1 - 0.068 12.5 0.9 0.47 9.7 0.4 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KFP05669.1 - 0.16 10.8 0.2 37 3.0 0.0 3.0 3 0 0 3 3 3 0 Tryptophan halogenase DAO PF01266.24 KFP05669.1 - 2.7 7.5 10.1 4.7 6.7 0.1 3.7 3 1 1 4 4 4 0 FAD dependent oxidoreductase tRNA-synt_1g PF09334.11 KFP05670.1 - 1.3e-68 231.6 0.0 3.3e-68 230.2 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KFP05670.1 - 5.2e-12 44.8 0.0 2.9e-10 39.1 0.0 2.6 2 1 1 3 3 3 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KFP05670.1 - 2.9e-05 24.1 0.0 4.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KFP05670.1 - 0.00035 20.0 0.0 0.00051 19.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain RRM_1 PF00076.22 KFP05671.1 - 2.1e-15 56.3 0.1 3.1e-15 55.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFP05671.1 - 0.049 13.6 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF1314 PF07013.11 KFP05671.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) Mito_carr PF00153.27 KFP05672.1 - 1.3e-39 134.1 0.1 3.9e-20 71.6 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein RRM_1 PF00076.22 KFP05673.1 - 4.3e-07 29.6 0.0 1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP05673.1 - 0.0096 16.0 0.1 0.26 11.4 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif RhoGAP PF00620.27 KFP05674.1 - 8.8e-40 136.0 0.5 3.1e-29 101.7 0.0 2.5 3 0 0 3 3 3 2 RhoGAP domain RGCC PF15151.6 KFP05675.1 - 8e-42 142.7 0.5 9.9e-42 142.4 0.5 1.1 1 0 0 1 1 1 1 Response gene to complement 32 protein family FAM184 PF15665.5 KFP05675.1 - 0.075 12.8 0.0 0.093 12.5 0.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Voltage_CLC PF00654.20 KFP05676.1 - 6.7e-99 331.5 20.9 6.7e-99 331.5 20.9 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KFP05676.1 - 9.8e-15 54.8 2.4 2e-06 28.2 0.1 2.5 2 0 0 2 2 2 2 CBS domain TNF PF00229.18 KFP05677.1 - 1.4e-37 128.5 0.1 2.2e-37 127.8 0.1 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family I-set PF07679.16 KFP05678.1 - 1.6e-13 50.6 0.0 2.1e-09 37.3 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP05678.1 - 2.5e-13 50.4 0.2 3.3e-09 37.2 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFP05678.1 - 1.6e-10 41.1 0.0 9e-07 29.1 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 KFP05678.1 - 4.6e-08 33.3 0.2 6.4e-07 29.6 0.1 2.1 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 KFP05678.1 - 2.2e-06 27.8 0.1 0.00039 20.6 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 KFP05678.1 - 0.008 15.7 0.0 0.61 9.7 0.0 2.7 3 0 0 3 3 3 1 Immunoglobulin domain Flo11 PF10182.9 KFP05678.1 - 0.036 14.2 0.0 0.063 13.4 0.0 1.3 1 0 0 1 1 1 0 Flo11 domain TauD PF02668.16 KFP05679.1 - 1e-38 133.7 0.2 1.4e-38 133.3 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KFP05679.1 - 3.9e-13 49.8 0.1 7.3e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KFP05679.1 - 0.0015 17.7 0.0 0.0066 15.6 0.0 1.8 2 0 0 2 2 2 1 CsiD Pou PF00157.17 KFP05680.1 - 2.7e-31 107.4 0.0 5e-31 106.5 0.0 1.5 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KFP05680.1 - 4.5e-18 64.8 1.7 1e-17 63.7 1.7 1.6 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 KFP05680.1 - 9.2e-05 22.7 0.2 0.014 15.7 0.0 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain Homeobox_KN PF05920.11 KFP05680.1 - 0.035 14.0 0.1 0.071 13.0 0.1 1.5 1 0 0 1 1 1 0 Homeobox KN domain DUF4770 PF15994.5 KFP05680.1 - 0.058 13.6 0.7 0.071 13.3 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) HTH_19 PF12844.7 KFP05680.1 - 0.1 12.6 0.0 2 8.5 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain 7tm_1 PF00001.21 KFP05682.1 - 5.5e-31 107.8 10.3 1.1e-30 106.8 10.3 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP05682.1 - 3e-05 23.5 9.8 0.001 18.5 0.4 3.2 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 KFP05682.1 - 0.0065 15.8 10.0 0.011 15.1 2.0 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw RNA_pol_L_2 PF13656.6 KFP05683.1 - 4.8e-27 93.5 0.0 5.4e-27 93.4 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KFP05683.1 - 1.1e-09 37.6 0.0 1.8e-09 36.9 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Synaptobrevin PF00957.21 KFP05684.1 - 1.8e-28 98.2 2.8 2.8e-28 97.6 2.8 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KFP05684.1 - 1.4e-27 95.5 0.7 2.5e-27 94.7 0.7 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain RIFIN PF02009.16 KFP05684.1 - 0.0078 16.1 1.6 0.0099 15.8 1.6 1.2 1 0 0 1 1 1 1 Rifin Pox_EPC_I2-L1 PF12575.8 KFP05684.1 - 1.5 9.1 6.5 1.4 9.2 2.0 2.7 2 1 1 3 3 3 0 Poxvirus entry protein complex L1 and I2 SLAIN PF15301.6 KFP05685.1 - 1e-135 453.4 49.1 5e-116 388.5 44.1 2.0 1 1 1 2 2 2 2 SLAIN motif-containing family LIM PF00412.22 KFP05686.1 - 0.002 18.3 14.4 0.0028 17.8 14.4 1.3 1 0 0 1 1 1 1 LIM domain Endonuclease_7 PF02945.15 KFP05686.1 - 2.1 8.3 9.3 3.3 7.7 9.3 1.3 1 0 0 1 1 1 0 Recombination endonuclease VII 3Beta_HSD PF01073.19 KFP05687.1 - 1.2e-68 231.1 0.0 1.5e-68 230.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFP05687.1 - 2.4e-37 128.7 0.0 3e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFP05687.1 - 1.1e-18 67.7 0.0 1.7e-17 63.8 0.0 2.2 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KFP05687.1 - 7.1e-15 55.4 0.0 9.5e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KFP05687.1 - 1.6e-14 53.7 0.0 2.3e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KFP05687.1 - 5.1e-09 35.7 0.0 0.00043 19.5 0.0 2.4 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KFP05687.1 - 2.2e-07 30.3 0.0 1.8e-06 27.3 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KFP05687.1 - 1.2e-06 28.2 0.0 2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_2 PF03446.15 KFP05687.1 - 0.031 14.4 0.0 0.058 13.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.10 KFP05687.1 - 0.1 12.5 0.1 2.3 8.1 0.0 2.2 1 1 1 2 2 2 0 KR domain EF-hand_1 PF00036.32 KFP05688.1 - 1.7e-30 102.2 16.7 1.2e-08 33.9 0.8 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFP05688.1 - 2.1e-28 98.6 9.4 2.7e-14 53.4 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP05688.1 - 1.5e-23 80.7 10.3 4.4e-08 32.4 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KFP05688.1 - 4.4e-23 80.9 14.1 7.1e-12 45.0 0.7 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 KFP05688.1 - 1e-16 61.0 0.4 4.3e-07 30.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFP05688.1 - 1.4e-09 37.0 17.0 0.0028 17.1 0.1 4.6 4 1 1 5 5 5 3 EF hand EF-hand_4 PF12763.7 KFP05688.1 - 1.7e-06 27.9 6.3 0.12 12.4 1.1 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 KFP05688.1 - 4.7e-05 23.6 1.8 0.17 12.3 0.2 2.6 1 1 1 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KFP05688.1 - 0.0018 18.6 2.2 0.82 10.0 0.5 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KFP05688.1 - 0.0039 17.3 0.2 0.26 11.5 0.1 2.5 2 1 0 2 2 2 1 Dockerin type I domain DUF853 PF05872.12 KFP05688.1 - 0.004 15.8 0.5 0.02 13.5 0.2 1.8 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF853) EF-hand_11 PF08976.11 KFP05688.1 - 0.0075 17.1 0.4 1.7 9.5 0.1 2.1 1 1 1 2 2 2 1 EF-hand domain SurA_N_3 PF13624.6 KFP05688.1 - 0.012 15.4 3.3 0.45 10.3 1.0 2.2 1 1 1 2 2 2 0 SurA N-terminal domain Sigma54_CBD PF04963.13 KFP05688.1 - 0.034 14.0 0.5 0.047 13.5 0.5 1.2 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain SUB1_ProdP9 PF18213.1 KFP05688.1 - 0.037 13.9 2.2 0.049 13.5 0.5 1.9 1 1 1 2 2 2 0 SUB1 protease Prodomain ProdP9 SurA_N_2 PF13623.6 KFP05688.1 - 0.062 13.2 4.2 1.1 9.2 0.5 2.8 1 1 1 2 2 2 0 SurA N-terminal domain Gp-FAR-1 PF05823.12 KFP05688.1 - 0.4 11.0 0.2 0.4 11.0 0.2 3.1 1 1 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) SRI PF08236.11 KFP05688.1 - 1 9.6 8.0 1 9.6 0.1 3.3 2 1 1 3 3 3 0 SRI (Set2 Rpb1 interacting) domain DUF2757 PF10955.8 KFP05688.1 - 2.6 8.4 4.7 4.9 7.5 0.4 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF2757) DJ-1_PfpI PF01965.24 KFP05689.1 - 0.00026 20.8 0.3 0.00072 19.4 0.3 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family DUF587 PF04532.12 KFP05689.1 - 0.039 13.2 0.1 0.06 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF587) Sua5_yciO_yrdC PF01300.18 KFP05690.1 - 2.3e-30 105.4 0.0 3.3e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination Gpr1_Fun34_YaaH PF01184.19 KFP05690.1 - 0.00013 21.7 18.2 0.00013 21.7 18.2 4.3 3 2 1 4 4 4 1 GPR1/FUN34/yaaH family YpmT PF17431.2 KFP05690.1 - 0.94 9.6 10.0 0.79 9.8 0.9 3.3 2 0 0 2 2 2 0 Uncharacterized YmpT-like MmgE_PrpD PF03972.14 KFP05691.1 - 6e-124 413.9 0.0 7.2e-124 413.7 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF927 PF06048.11 KFP05691.1 - 0.11 12.0 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF927) Glyoxalase PF00903.25 KFP05692.1 - 1.2e-10 41.6 0.0 2e-10 40.9 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 KFP05692.1 - 0.0011 18.9 0.1 0.0046 16.9 0.1 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KFP05692.1 - 0.043 13.9 0.0 0.09 12.9 0.0 1.6 1 1 1 2 2 2 0 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KFP05692.1 - 0.093 13.0 0.0 0.26 11.6 0.0 1.8 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily zf-C2H2 PF00096.26 KFP05694.1 - 9.5e-15 54.1 25.1 4.3e-05 23.7 0.6 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP05694.1 - 1.3e-09 38.0 10.6 8.3e-06 26.0 3.3 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP05694.1 - 1.3e-06 28.8 23.2 0.03 15.1 3.9 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFP05694.1 - 0.0089 16.6 6.2 0.35 11.5 0.2 2.5 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 KFP05694.1 - 0.23 11.3 4.7 0.14 12.0 2.1 2.0 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 KFP05694.1 - 1.9 8.6 5.6 18 5.4 2.0 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger zf-H2C2_2 PF13465.6 KFP05695.1 - 2e-10 40.6 11.6 3.8e-05 23.9 0.8 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFP05695.1 - 6.9e-10 38.8 11.2 0.00011 22.5 0.7 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP05695.1 - 0.00031 21.3 10.1 0.025 15.4 0.8 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KFP05695.1 - 0.0045 17.2 0.8 1.9 8.6 0.1 2.1 2 0 0 2 2 2 2 Aberrant zinc-finger FOXP-CC PF16159.5 KFP05695.1 - 0.069 13.8 3.7 1.4 9.6 0.5 2.2 1 1 1 2 2 2 0 FOXP coiled-coil domain Gtr1_RagA PF04670.12 KFP05696.1 - 1.3e-108 361.7 1.2 1.6e-108 361.4 1.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KFP05696.1 - 7.7e-09 35.8 0.0 2.8e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP05696.1 - 1e-08 34.9 0.0 2.3e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KFP05696.1 - 2.1e-08 33.8 0.1 3.7e-08 33.0 0.0 1.5 1 1 1 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP05696.1 - 9.5e-07 28.9 0.0 3.1e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP05696.1 - 0.0016 18.1 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFP05696.1 - 0.0051 16.3 0.0 0.009 15.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF815 PF05673.13 KFP05696.1 - 0.018 14.2 2.4 0.21 10.7 0.8 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 KFP05696.1 - 0.026 14.3 0.2 0.092 12.5 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 KFP05696.1 - 0.027 15.0 0.2 0.053 14.0 0.2 1.6 1 1 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 KFP05696.1 - 0.039 13.8 0.2 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase SecA_DEAD PF07517.14 KFP05696.1 - 0.052 12.8 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain AAA_24 PF13479.6 KFP05696.1 - 0.078 12.7 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 KFP05696.1 - 0.18 11.5 0.0 0.24 11.2 0.0 1.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_29 PF13555.6 KFP05696.1 - 0.21 11.4 0.3 0.4 10.4 0.3 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 KFP05696.1 - 1.2 8.2 7.9 5.6 6.0 0.8 2.9 2 1 1 3 3 3 0 G-protein alpha subunit DUF5099 PF17025.5 KFP05696.1 - 2.5 8.5 5.7 19 5.7 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5099) DUF4606 PF15379.6 KFP05697.1 - 2.2e-38 130.6 1.0 2.5e-38 130.5 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4606) Myotub-related PF06602.14 KFP05698.1 - 6.6e-145 482.5 0.0 8.6e-145 482.1 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 KFP05698.1 - 0.00056 19.5 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase GRAM PF02893.20 KFP05698.1 - 0.00082 19.2 0.0 0.0025 17.7 0.0 1.8 2 0 0 2 2 2 1 GRAM domain Vps36_ESCRT-II PF11605.8 KFP05698.1 - 0.0022 18.1 0.1 0.0038 17.4 0.1 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Y_phosphatase2 PF03162.13 KFP05698.1 - 0.0025 17.4 0.1 0.15 11.6 0.1 2.5 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 KFP05698.1 - 0.0046 16.8 0.1 0.028 14.3 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP05698.1 - 0.012 15.5 0.1 0.034 14.1 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family WTX PF09422.10 KFP05699.1 - 1.9e-63 215.2 23.5 2.4e-25 89.6 1.2 3.0 2 1 1 3 3 3 3 WTX protein RhoGEF PF00621.20 KFP05701.1 - 1.3e-43 149.3 2.8 1.3e-43 149.3 2.8 1.9 2 1 0 2 2 2 1 RhoGEF domain SH3_1 PF00018.28 KFP05701.1 - 1.9e-10 40.2 1.8 3.9e-10 39.2 1.8 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP05701.1 - 1.1e-09 37.8 0.0 2.9e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFP05701.1 - 3.6e-09 36.3 0.1 7.5e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 KFP05701.1 - 3.9e-07 30.5 0.4 8.4e-07 29.5 0.4 1.6 1 0 0 1 1 1 1 PH domain Pkinase_Tyr PF07714.17 KFP05702.1 - 1.3e-105 352.4 0.0 1.9e-105 351.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP05702.1 - 1.9e-41 142.2 0.0 1.6e-28 99.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain I-set PF07679.16 KFP05702.1 - 1.3e-33 114.9 1.6 6.2e-19 67.9 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP05702.1 - 4.2e-29 101.0 5.3 2.8e-14 53.5 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KFP05702.1 - 1.3e-22 79.9 4.1 4.1e-10 39.9 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFP05702.1 - 1.3e-22 79.7 3.6 1.2e-10 41.4 0.6 3.7 3 1 0 3 3 3 2 Immunoglobulin domain VEGFR-2_TMD PF17988.1 KFP05702.1 - 3.4e-18 64.8 0.7 7.7e-18 63.6 0.7 1.6 1 0 0 1 1 1 1 VEGFR-2 Transmembrane domain V-set PF07686.17 KFP05702.1 - 5.2e-11 42.7 7.2 0.00019 21.6 1.4 5.1 3 2 1 4 4 4 2 Immunoglobulin V-set domain Ig_5 PF16681.5 KFP05702.1 - 8.3e-10 38.9 2.8 0.0026 18.1 0.0 3.6 3 0 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFP05702.1 - 9.4e-09 35.4 2.5 0.0015 18.7 0.0 3.6 3 1 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFP05702.1 - 8e-05 22.1 0.0 2.4 7.8 0.0 3.4 3 0 0 3 3 3 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFP05702.1 - 0.0013 18.8 0.6 2.3 8.4 0.0 3.2 4 0 0 4 4 4 2 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 KFP05702.1 - 0.0015 18.5 0.2 0.027 14.5 0.0 2.4 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Haspin_kinase PF12330.8 KFP05702.1 - 0.0053 15.7 0.1 0.022 13.7 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Adeno_E3_CR1 PF02440.15 KFP05702.1 - 0.006 16.3 1.2 0.38 10.5 0.2 3.1 3 0 0 3 3 3 1 Adenovirus E3 region protein CR1 Ig_C17orf99 PF17736.1 KFP05702.1 - 0.0077 16.2 0.6 17 5.5 0.0 3.5 3 1 0 3 3 3 0 C17orf99 Ig domain ADH_N PF08240.12 KFP05702.1 - 0.054 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain PMC2NT PF08066.12 KFP05702.1 - 0.056 14.1 0.4 0.14 12.8 0.4 1.6 1 0 0 1 1 1 0 PMC2NT (NUC016) domain C2-set PF05790.15 KFP05702.1 - 0.13 12.4 0.5 5 7.4 0.2 2.8 2 1 0 2 2 2 0 Immunoglobulin C2-set domain TNF PF00229.18 KFP05702.1 - 0.16 11.9 0.9 2.7 7.9 0.5 2.3 2 0 0 2 2 2 0 TNF(Tumour Necrosis Factor) family C1-set PF07654.15 KFP05702.1 - 0.17 12.3 0.6 4.5 7.7 0.4 2.4 2 0 0 2 2 2 0 Immunoglobulin C1-set domain Caudal_act PF04731.12 KFP05703.1 - 1.5e-53 180.8 13.7 1.8e-53 180.5 13.7 1.1 1 0 0 1 1 1 1 Caudal like protein activation region Homeodomain PF00046.29 KFP05703.1 - 3.6e-20 71.6 6.0 5.5e-20 71.0 6.0 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP05703.1 - 0.0073 16.2 0.9 0.014 15.2 0.9 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 KFP05703.1 - 0.13 11.7 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez O-antigen_lig PF13425.6 KFP05703.1 - 5.7 5.6 5.5 7 5.3 5.5 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Caudal_act PF04731.12 KFP05704.1 - 1.4e-50 171.2 12.9 1.7e-50 170.9 12.9 1.1 1 0 0 1 1 1 1 Caudal like protein activation region Homeodomain PF00046.29 KFP05704.1 - 9.7e-22 76.6 3.2 1.5e-21 76.0 3.2 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP05704.1 - 0.0022 17.8 0.3 0.0045 16.9 0.3 1.5 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 KFP05704.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Erf4 PF10256.9 KFP05705.1 - 1.7e-10 41.1 0.0 2.1e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Fip1 PF05182.13 KFP05706.1 - 5.6e-26 89.8 1.8 8.7e-26 89.2 1.8 1.3 1 0 0 1 1 1 1 Fip1 motif DUF5404 PF17397.2 KFP05706.1 - 3.2e-11 43.6 0.9 5e-11 42.9 0.9 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5404) Cwf_Cwc_15 PF04889.12 KFP05706.1 - 6.1 6.5 8.7 7.9 6.1 8.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RSRP PF17069.5 KFP05707.1 - 0.19 11.2 33.2 0.24 10.9 33.2 1.1 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 PDZ PF00595.24 KFP05708.1 - 1e-62 208.5 3.3 3.4e-16 59.4 0.1 4.2 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 KFP05708.1 - 9.7e-34 115.0 0.9 5.7e-08 32.5 0.1 4.4 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 KFP05708.1 - 1.2e-18 67.2 0.6 0.0069 16.7 0.0 4.4 4 0 0 4 4 4 4 PDZ domain zf-C3HC4 PF00097.25 KFP05708.1 - 2.7e-07 30.3 8.6 6.8e-07 29.1 8.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP05708.1 - 5.3e-07 29.6 7.1 1.3e-06 28.3 7.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFP05708.1 - 1.4e-06 28.1 3.5 4e-06 26.6 3.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP05708.1 - 1.4e-06 28.0 9.7 1.4e-06 28.0 9.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP05708.1 - 9.8e-06 25.8 6.7 9.8e-06 25.8 6.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KFP05708.1 - 1.2e-05 25.2 6.6 3.7e-05 23.6 6.6 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFP05708.1 - 2e-05 24.7 9.4 6.5e-05 23.0 9.4 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Tricorn_PDZ PF14685.6 KFP05708.1 - 0.00011 22.0 0.2 21 5.2 0.0 4.2 4 0 0 4 4 4 0 Tricorn protease PDZ domain U-box PF04564.15 KFP05708.1 - 0.001 19.2 0.3 0.026 14.7 0.1 2.8 1 1 1 2 2 2 1 U-box domain zf-rbx1 PF12678.7 KFP05708.1 - 0.0037 17.5 4.8 0.013 15.8 4.8 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain SR-25 PF10500.9 KFP05708.1 - 0.009 15.7 1.5 0.009 15.7 1.5 1.9 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Prok-RING_4 PF14447.6 KFP05708.1 - 0.13 12.2 8.1 0.38 10.7 8.1 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 LCE PF14672.6 KFP05708.1 - 0.34 11.5 5.6 0.068 13.8 1.6 1.9 2 0 0 2 2 1 0 Late cornified envelope Ras PF00071.22 KFP05709.1 - 3.9e-23 81.8 0.0 1.6e-22 79.8 0.0 1.8 1 1 0 1 1 1 1 Ras family Arf PF00025.21 KFP05709.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family UCH PF00443.29 KFP05710.1 - 2e-59 201.2 2.7 2.4e-59 200.9 2.7 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP05710.1 - 5.4e-31 108.4 4.0 7.1e-31 108.0 4.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KFP05710.1 - 0.00011 21.8 11.0 0.0009 18.8 8.8 2.4 2 1 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase NapB PF03892.14 KFP05710.1 - 0.14 12.1 2.4 0.36 10.8 2.4 1.7 1 0 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) CEBP_ZZ PF16366.5 KFP05710.1 - 1.3 9.3 6.9 0.56 10.5 1.3 2.4 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain 7tm_1 PF00001.21 KFP05711.1 - 4.8e-29 101.5 12.8 5.6e-29 101.3 12.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MFS_1 PF07690.16 KFP05712.1 - 2e-25 89.5 42.7 3.9e-16 58.9 21.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFP05712.1 - 0.00065 18.4 22.0 0.073 11.6 5.2 3.3 2 1 0 3 3 3 3 MFS/sugar transport protein Phage_holin_2_4 PF16082.5 KFP05712.1 - 0.085 12.6 2.5 9.7 6.0 0.1 3.3 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like zf-RING_2 PF13639.6 KFP05713.1 - 3.5e-13 49.6 8.0 5.5e-13 49.0 8.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFP05713.1 - 3.5e-10 40.0 4.8 7e-10 39.0 4.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KFP05713.1 - 1.6e-08 34.1 3.4 1.6e-08 34.1 3.4 1.7 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFP05713.1 - 4.8e-08 32.7 6.2 7.4e-08 32.1 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP05713.1 - 1.9e-06 27.6 7.6 3.1e-06 26.9 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP05713.1 - 4.3e-05 23.4 6.3 6.8e-05 22.7 6.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KFP05713.1 - 4.6e-05 23.4 1.4 9.6e-05 22.4 1.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KFP05713.1 - 0.00057 19.7 4.7 0.00096 19.0 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP05713.1 - 0.0017 18.1 4.5 0.003 17.4 4.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFP05713.1 - 0.005 16.8 4.0 0.01 15.8 4.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KFP05713.1 - 0.15 11.7 5.1 0.23 11.1 5.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-HC5HC2H_2 PF13832.6 KFP05713.1 - 0.16 12.1 1.2 0.3 11.2 1.2 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_4 PF14570.6 KFP05713.1 - 0.17 11.7 4.5 0.32 10.8 4.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KFP05713.1 - 0.25 11.7 6.2 0.41 11.0 6.2 1.3 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 KFP05713.1 - 1.1 9.4 7.4 2.3 8.4 7.4 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KFP05713.1 - 2.2 8.5 5.2 7.7 6.8 5.2 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain DUF4683 PF15735.5 KFP05714.1 - 4.4e-126 421.7 6.8 4.4e-126 421.7 6.8 3.8 4 1 0 4 4 4 1 Domain of unknown function (DUF4683) RVT_1 PF00078.27 KFP05715.1 - 0.0055 16.3 0.0 0.0087 15.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ABC_membrane PF00664.23 KFP05716.1 - 1.8e-37 129.5 8.1 2.3e-37 129.1 8.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFP05716.1 - 2.6e-34 118.7 0.0 5.1e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFP05716.1 - 9.7e-07 28.4 0.0 0.00032 20.2 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFP05716.1 - 0.0021 18.5 0.0 0.0062 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.17 KFP05716.1 - 0.01 16.0 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 KFP05716.1 - 0.011 15.5 0.2 0.011 15.5 0.2 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_28 PF13521.6 KFP05716.1 - 0.022 15.0 0.0 0.095 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KFP05716.1 - 0.023 14.9 0.1 0.16 12.2 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFP05716.1 - 0.048 13.4 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KFP05716.1 - 0.088 12.0 0.0 0.24 10.5 0.0 1.6 2 0 0 2 2 2 0 G-protein alpha subunit HEAT_2 PF13646.6 KFP05716.1 - 0.092 13.2 0.0 0.33 11.4 0.0 1.9 2 0 0 2 2 2 0 HEAT repeats AAA_18 PF13238.6 KFP05716.1 - 0.12 13.0 0.1 0.48 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFP05716.1 - 0.18 11.3 0.0 0.55 9.7 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_23 PF13476.6 KFP05716.1 - 0.61 10.6 2.2 0.74 10.3 0.0 2.1 3 0 0 3 3 3 0 AAA domain UPRTase PF14681.6 KFP05717.1 - 1.3e-36 126.0 0.0 9.8e-30 103.5 0.0 2.1 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KFP05717.1 - 0.00014 21.4 0.0 0.00017 21.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DHHC PF01529.20 KFP05718.1 - 3e-36 124.5 16.5 3e-36 124.5 16.5 2.1 2 0 0 2 2 2 2 DHHC palmitoyltransferase Spt4 PF06093.13 KFP05718.1 - 3.4 7.8 8.2 4.4 7.5 6.9 1.8 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger FGF PF00167.18 KFP05719.1 - 4.8e-34 117.2 0.1 5.4e-34 117.0 0.1 1.0 1 0 0 1 1 1 1 Fibroblast growth factor MecA PF05389.12 KFP05719.1 - 0.18 11.4 0.1 0.21 11.2 0.1 1.1 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) SNF2_N PF00176.23 KFP05720.1 - 7.8e-62 209.0 0.0 7.8e-62 209.0 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain ADD_ATRX PF17981.1 KFP05720.1 - 6.8e-31 105.9 1.7 1.7e-30 104.7 1.7 1.7 1 0 0 1 1 1 1 Cysteine Rich ADD domain Helicase_C PF00271.31 KFP05720.1 - 4.6e-15 55.9 0.0 2.1e-14 53.8 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OST3_OST6 PF04756.13 KFP05721.1 - 1.3e-106 356.3 0.0 1.5e-106 356.1 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 KFP05721.1 - 4.2e-05 23.5 0.0 6.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF4131 PF13567.6 KFP05721.1 - 0.51 10.0 3.7 0.38 10.4 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) COX7B PF05392.11 KFP05722.1 - 1.6e-38 130.2 0.1 1.7e-38 130.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase chain VIIB HMA PF00403.26 KFP05723.1 - 1.2e-87 288.2 13.5 3.5e-14 53.0 0.1 7.6 7 0 0 7 7 7 6 Heavy-metal-associated domain Hydrolase PF00702.26 KFP05723.1 - 2.7e-61 207.5 0.3 6e-61 206.4 0.3 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFP05723.1 - 3.7e-46 156.9 2.9 3.7e-46 156.9 2.9 1.9 2 0 0 2 2 2 1 E1-E2 ATPase RRM_3 PF08777.11 KFP05723.1 - 4.6e-08 33.0 0.0 0.59 10.2 0.0 5.4 5 0 0 5 5 5 2 RNA binding motif Hydrolase_3 PF08282.12 KFP05723.1 - 3.5e-06 26.9 2.6 0.00032 20.5 1.5 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KFP05723.1 - 0.0043 17.1 0.3 0.024 14.7 0.1 2.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase CT_C_D PF02682.16 KFP05723.1 - 0.0087 15.8 0.0 4.6 6.9 0.0 3.5 3 0 0 3 3 3 1 Carboxyltransferase domain, subdomain C and D HAD_2 PF13419.6 KFP05723.1 - 0.013 15.6 0.1 0.036 14.1 0.1 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF2997 PF11211.8 KFP05723.1 - 9.3 6.1 17.0 0.92 9.3 0.6 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF2997) Ig_3 PF13927.6 KFP05724.1 - 2.3e-14 53.8 1.5 4.8e-10 39.9 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP05724.1 - 9.8e-11 41.6 0.2 5.5e-07 29.6 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFP05724.1 - 3.5e-10 39.9 0.6 2.1e-05 24.6 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFP05724.1 - 1.8e-08 34.6 2.0 0.00019 21.6 0.1 3.7 2 2 1 3 3 3 2 Immunoglobulin V-set domain Ig_2 PF13895.6 KFP05724.1 - 5.3e-08 33.1 1.7 0.0018 18.6 0.0 2.2 1 1 1 2 2 2 2 Immunoglobulin domain Ig_4 PF16680.5 KFP05724.1 - 1.5e-06 28.3 0.1 0.1 12.9 0.0 2.6 3 0 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain V-set_CD47 PF08204.11 KFP05724.1 - 0.006 16.6 0.5 0.14 12.2 0.4 2.7 2 1 0 2 2 2 1 CD47 immunoglobulin-like domain PARP PF00644.20 KFP05725.1 - 2.5e-14 53.3 0.3 5.6e-14 52.2 0.3 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ARTD15_N PF18084.1 KFP05725.1 - 3.1e-05 24.1 0.3 0.00012 22.3 0.1 2.1 2 0 0 2 2 2 1 ARTD15 N-terminal domain LIM PF00412.22 KFP05726.1 - 7.5e-21 74.1 16.1 6e-13 48.8 9.8 2.3 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 KFP05726.1 - 3.1e-15 55.7 0.2 5.2e-15 55.0 0.2 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP05726.1 - 3.6e-05 23.6 0.0 9.3e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain NinD PF17466.2 KFP05726.1 - 0.00078 19.5 2.5 0.03 14.4 0.1 2.5 2 0 0 2 2 2 1 Family of unknown function MerR_1 PF13411.6 KFP05726.1 - 0.13 12.3 0.1 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 MerR HTH family regulatory protein c-SKI_SMAD_bind PF08782.10 KFP05726.1 - 6.5 7.1 14.0 0.9 9.8 1.1 3.1 2 1 1 3 3 3 0 c-SKI Smad4 binding domain eRF1_1 PF03463.15 KFP05727.1 - 1.4e-49 167.4 0.1 2.3e-49 166.7 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 KFP05727.1 - 2.2e-35 121.8 0.1 4e-35 121.0 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KFP05727.1 - 1.2e-26 93.4 0.1 3.5e-26 91.9 0.0 1.8 2 0 0 2 2 2 1 eRF1 domain 3 Integrin_alpha2 PF08441.12 KFP05728.1 - 2e-55 188.5 8.4 3.2e-55 187.9 8.4 1.3 1 0 0 1 1 1 1 Integrin alpha VWA PF00092.28 KFP05728.1 - 1.9e-40 139.0 0.6 3.2e-40 138.2 0.6 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain FG-GAP PF01839.23 KFP05728.1 - 1.2e-16 60.5 8.4 3.7e-08 33.3 0.8 3.7 3 0 0 3 3 3 2 FG-GAP repeat VWA_2 PF13519.6 KFP05728.1 - 1.3e-13 51.5 0.1 3e-13 50.4 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VCBS PF13517.6 KFP05728.1 - 1.8e-06 28.5 5.8 0.0084 16.7 0.2 3.9 4 0 0 4 4 4 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 KFP05728.1 - 2.6e-06 27.6 2.1 0.17 12.2 0.2 4.9 5 0 0 5 5 5 2 FG-GAP repeat LYRIC PF15686.5 KFP05728.1 - 0.053 13.1 0.3 0.08 12.5 0.3 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Integrin_alpha PF00357.20 KFP05728.1 - 0.095 12.7 4.4 0.22 11.6 4.4 1.7 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region Kazal_2 PF07648.15 KFP05729.1 - 2.9e-37 126.5 39.4 2.8e-14 53.0 3.4 4.4 5 0 0 5 5 5 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFP05729.1 - 1.9e-17 63.0 35.6 1.1e-06 28.5 7.9 4.0 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain FOLN PF09289.10 KFP05729.1 - 1.7e-07 31.2 13.6 1.7e-07 31.2 13.6 4.8 5 1 0 5 5 5 2 Follistatin/Osteonectin-like EGF domain ETC_C1_NDUFA4 PF04800.12 KFP05730.1 - 8.7e-29 99.6 1.0 1.1e-28 99.3 0.2 1.5 2 0 0 2 2 2 1 ETC complex I subunit conserved region DUF2188 PF09954.9 KFP05730.1 - 0.011 15.9 0.1 0.03 14.5 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Arf PF00025.21 KFP05731.1 - 8.3e-30 103.5 0.0 9.7e-30 103.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFP05731.1 - 2.2e-09 37.5 0.0 2.8e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFP05731.1 - 4.8e-07 29.4 0.0 5.9e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KFP05731.1 - 5.6e-07 29.3 0.0 6.3e-07 29.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KFP05731.1 - 9.3e-05 21.9 0.0 0.00011 21.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KFP05731.1 - 0.00026 20.3 0.7 0.064 12.4 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KFP05731.1 - 0.0009 19.3 0.0 0.0033 17.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFP05731.1 - 0.0017 18.8 0.0 0.0026 18.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KFP05731.1 - 0.0019 18.7 0.0 0.0027 18.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KFP05731.1 - 0.0035 17.5 0.0 0.0036 17.5 0.0 1.3 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 KFP05731.1 - 0.0091 15.9 0.1 0.21 11.5 0.1 2.1 1 1 0 1 1 1 1 NACHT domain ABC_tran PF00005.27 KFP05731.1 - 0.014 16.0 0.4 0.11 13.1 0.4 2.0 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KFP05731.1 - 0.016 15.5 0.0 0.021 15.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 KFP05731.1 - 0.017 14.7 0.0 0.25 10.9 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 KFP05731.1 - 0.053 13.6 0.0 0.072 13.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFP05731.1 - 0.056 13.8 0.1 0.14 12.5 0.1 1.7 1 1 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.17 KFP05731.1 - 0.11 12.2 0.0 5.6 6.7 0.1 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 KFP05731.1 - 0.12 12.1 0.0 4 7.2 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KFP05731.1 - 0.13 11.7 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KFP05731.1 - 0.15 11.7 0.0 0.18 11.5 0.0 1.3 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFP05731.1 - 0.16 11.9 0.5 0.32 10.9 0.4 1.5 1 1 0 1 1 1 0 RsgA GTPase HSP20 PF00011.21 KFP05732.1 - 1.4e-14 54.1 0.0 2.5e-14 53.3 0.0 1.4 2 0 0 2 2 2 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KFP05732.1 - 0.023 14.3 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 HSP20-like domain found in ArsA HrpB1_HrpK PF09613.10 KFP05732.1 - 0.17 11.5 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) BAR_3_WASP_bdg PF10456.9 KFP05733.1 - 1.3e-106 355.4 6.0 1.8e-106 354.9 6.0 1.2 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.24 KFP05733.1 - 4.1e-23 81.5 0.7 7.8e-23 80.6 0.0 1.8 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 KFP05733.1 - 0.013 15.1 2.9 0.013 15.1 2.9 2.3 2 0 0 2 2 2 0 Vps5 C terminal like HBM PF16591.5 KFP05733.1 - 0.084 12.3 0.1 0.25 10.7 0.0 1.7 1 1 0 1 1 1 0 Helical bimodular sensor domain BAR PF03114.18 KFP05733.1 - 0.53 9.9 7.0 0.064 12.9 2.9 1.5 2 0 0 2 2 2 0 BAR domain IGFBP PF00219.18 KFP05734.1 - 8e-09 36.0 20.5 8e-09 36.0 20.5 2.4 2 0 0 2 2 2 1 Insulin-like growth factor binding protein ANAPC4_WD40 PF12894.7 KFP05735.1 - 0.00082 19.6 0.1 0.6 10.5 0.0 2.1 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFP05735.1 - 0.013 16.4 2.4 0.25 12.3 0.2 2.8 3 0 0 3 3 3 0 WD domain, G-beta repeat GSHPx PF00255.19 KFP05736.1 - 4.3e-36 122.8 0.1 5.7e-36 122.4 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KFP05736.1 - 1.4e-07 31.4 0.0 2.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFP05736.1 - 0.0031 17.2 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 Redoxin HA2 PF04408.23 KFP05737.1 - 5.6e-16 58.8 0.0 5.6e-16 58.8 0.0 3.0 3 1 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFP05737.1 - 2.5e-15 56.6 0.1 1.7e-14 53.9 0.0 2.5 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFP05737.1 - 2e-12 47.5 0.1 7.8e-12 45.5 0.1 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFP05737.1 - 9.8e-11 41.7 0.0 2.4e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFP05737.1 - 8.7e-06 26.1 0.2 2.6e-05 24.5 0.2 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KFP05737.1 - 0.011 14.8 0.2 0.026 13.6 0.2 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KFP05737.1 - 0.03 14.2 0.1 0.79 9.6 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 KFP05737.1 - 0.046 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family ATPase PF06745.13 KFP05737.1 - 0.086 12.2 0.2 0.29 10.4 0.0 1.9 2 0 0 2 2 2 0 KaiC ABC_tran PF00005.27 KFP05737.1 - 0.12 12.9 4.8 0.76 10.3 0.0 3.0 3 0 0 3 3 3 0 ABC transporter rRNA_proc-arch PF13234.6 KFP05738.1 - 9.3e-88 294.6 2.2 1.7e-87 293.8 2.2 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 KFP05738.1 - 7.8e-59 198.0 1.0 1.5e-58 197.0 1.0 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KFP05738.1 - 1.1e-16 61.1 0.0 2.6e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP05738.1 - 1.6e-07 31.6 0.0 1.7e-06 28.3 0.0 2.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFP05738.1 - 0.023 15.0 0.0 0.18 12.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KFP05738.1 - 0.065 13.6 0.0 0.23 11.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain PAP2 PF01569.21 KFP05739.1 - 1.8e-27 95.7 1.5 1.8e-27 95.7 1.5 1.5 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KFP05739.1 - 0.011 16.3 2.9 0.011 16.3 2.9 2.2 2 0 0 2 2 2 0 PAP2 superfamily C-terminal COX4 PF02936.14 KFP05739.1 - 0.027 14.5 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Aa_trans PF01490.18 KFP05740.1 - 8.4e-23 80.7 39.2 9.4e-14 50.9 7.9 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein DEAD PF00270.29 KFP05741.1 - 2.9e-51 173.7 0.0 5e-51 173.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP05741.1 - 3.1e-31 108.0 0.3 3.8e-30 104.5 0.2 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP05741.1 - 0.012 15.6 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit fn3 PF00041.21 KFP05742.1 - 2.8e-26 91.7 6.5 2.1e-09 37.6 0.2 4.1 4 0 0 4 4 4 4 Fibronectin type III domain Big_5 PF13205.6 KFP05742.1 - 0.011 16.4 3.3 0.014 16.1 0.4 2.4 2 0 0 2 2 2 0 Bacterial Ig-like domain Pur_ac_phosph_N PF16656.5 KFP05742.1 - 0.03 14.9 15.3 4.1 8.0 0.1 3.8 3 1 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain RGI_lyase PF18370.1 KFP05742.1 - 0.064 13.6 0.2 0.22 11.9 0.2 1.9 1 0 0 1 1 1 0 Rhamnogalacturonan I lyases beta-sheet domain fn3 PF00041.21 KFP05743.1 - 3.2e-33 113.9 9.4 1.6e-09 38.0 0.5 5.4 5 0 0 5 5 5 4 Fibronectin type III domain Lep_receptor_Ig PF06328.11 KFP05743.1 - 1.5e-29 101.8 2.1 1.9e-29 101.4 0.6 2.0 2 0 0 2 2 2 1 Ig-like C2-type domain EpoR_lig-bind PF09067.10 KFP05743.1 - 5e-06 26.7 0.0 1.1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding IL6Ra-bind PF09240.10 KFP05743.1 - 0.00024 21.5 0.6 0.00093 19.6 0.0 2.3 2 0 0 2 2 2 1 Interleukin-6 receptor alpha chain, binding fn3_2 PF16893.5 KFP05743.1 - 0.00073 19.6 0.1 0.0077 16.4 0.1 2.5 2 0 0 2 2 2 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFP05743.1 - 0.036 14.6 11.4 0.34 11.5 0.0 3.9 4 1 0 4 4 4 0 Purple acid Phosphatase, N-terminal domain DUF4998 PF16389.5 KFP05743.1 - 0.048 13.2 0.1 1.5 8.4 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function IL4Ra_N PF09238.10 KFP05743.1 - 0.097 13.0 0.5 1.3 9.5 0.3 2.5 2 0 0 2 2 2 0 Interleukin-4 receptor alpha chain, N-terminal DUF3377 PF11857.8 KFP05743.1 - 0.2 11.6 0.3 0.49 10.4 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Ank_2 PF12796.7 KFP05744.1 - 1.2e-42 144.4 4.1 4e-10 40.2 0.0 4.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP05744.1 - 6.7e-36 122.2 6.1 1.1e-08 35.4 0.0 7.2 3 1 5 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP05744.1 - 6.8e-31 105.9 6.0 8.6e-08 32.3 0.0 6.5 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KFP05744.1 - 2.8e-29 100.3 9.0 1.8e-05 25.0 0.0 8.4 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 KFP05744.1 - 7.2e-28 93.6 3.2 0.00042 20.5 0.0 8.6 8 0 0 8 8 8 5 Ankyrin repeat Pkinase PF00069.25 KFP05745.1 - 1.9e-56 191.3 0.0 1.1e-55 188.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP05745.1 - 3.5e-32 111.7 0.1 5.5e-31 107.8 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase zf-RING_2 PF13639.6 KFP05745.1 - 2e-05 24.8 11.8 2e-05 24.8 11.8 2.3 2 0 0 2 2 1 1 Ring finger domain SWIM PF04434.17 KFP05745.1 - 6.5e-05 22.5 0.2 0.00013 21.5 0.2 1.6 1 0 0 1 1 1 1 SWIM zinc finger Kinase-like PF14531.6 KFP05745.1 - 7.3e-05 22.2 2.6 0.66 9.2 0.1 3.7 3 1 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 KFP05745.1 - 8.5e-05 21.5 1.0 0.00017 20.5 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase PHD PF00628.29 KFP05745.1 - 0.013 15.3 8.8 0.044 13.7 8.8 2.0 1 0 0 1 1 1 0 PHD-finger Phostensin_N PF13916.6 KFP05745.1 - 0.038 14.3 0.1 0.22 11.9 0.2 2.2 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal APH PF01636.23 KFP05745.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF5507 PF17612.2 KFP05745.1 - 0.084 12.6 0.2 0.23 11.1 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5507) FANCL_C PF11793.8 KFP05745.1 - 0.11 12.7 7.7 0.34 11.1 7.7 1.9 1 0 0 1 1 1 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KFP05745.1 - 0.19 11.8 4.7 0.52 10.4 4.7 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Di19 PF05605.12 KFP05745.1 - 0.57 10.5 6.1 65 3.9 6.4 2.8 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding SET PF00856.28 KFP05746.1 - 1.7e-05 25.3 0.0 2.8e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 SET domain ELM2 PF01448.24 KFP05747.1 - 8.9e-11 42.4 0.0 3e-10 40.7 0.0 1.9 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-binding PF00249.31 KFP05747.1 - 2.4e-06 27.7 0.2 5.2e-06 26.5 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain NEMO PF11577.8 KFP05747.1 - 0.0011 19.0 0.3 0.008 16.2 1.2 2.0 2 0 0 2 2 2 1 NF-kappa-B essential modulator NEMO Myb_DNA-bind_7 PF15963.5 KFP05747.1 - 0.0061 16.4 0.1 0.018 14.9 0.1 1.8 1 0 0 1 1 1 1 Myb DNA-binding like dUTPase PF00692.19 KFP05748.1 - 6.2e-17 61.5 0.0 8.9e-17 61.0 0.0 1.2 1 0 0 1 1 1 1 dUTPase Pkinase PF00069.25 KFP05750.1 - 2.6e-69 233.5 0.0 4e-69 232.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP05750.1 - 1.5e-36 126.1 0.0 2.3e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KFP05750.1 - 9.4e-35 118.6 2.0 4.3e-16 58.8 0.5 2.6 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_fungal PF17667.1 KFP05750.1 - 4.4e-06 25.7 0.0 8.1e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFP05750.1 - 0.00041 19.8 0.0 0.00061 19.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFP05750.1 - 0.28 11.1 0.8 20 5.0 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ras PF00071.22 KFP05751.1 - 3.2e-61 205.7 2.3 4e-61 205.3 2.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP05751.1 - 1.6e-33 115.5 1.1 2.5e-33 114.8 1.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP05751.1 - 3.8e-14 52.5 0.3 5.2e-14 52.1 0.3 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFP05751.1 - 9.3e-08 31.7 1.3 0.00015 21.2 0.1 2.1 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFP05751.1 - 0.00011 22.3 0.2 0.00023 21.2 0.1 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFP05751.1 - 0.00014 21.3 0.5 0.00021 20.8 0.5 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFP05751.1 - 0.00018 21.1 0.1 0.00063 19.3 0.1 1.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KFP05751.1 - 0.0036 16.9 0.0 2.8 7.5 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFP05751.1 - 0.0083 16.0 0.1 1 9.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 KFP05751.1 - 0.025 13.9 0.2 0.4 9.9 0.0 2.2 2 0 0 2 2 2 0 Septin DUF2757 PF10955.8 KFP05751.1 - 0.06 13.6 0.2 0.12 12.6 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2757) AAA_16 PF13191.6 KFP05751.1 - 0.099 13.0 0.0 0.18 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain CysA_C_terminal PF17850.1 KFP05752.1 - 0.24 12.0 3.3 37 5.0 3.3 3.0 1 1 0 1 1 1 0 CysA C-terminal regulatory domain Ribosomal_L4 PF00573.22 KFP05752.1 - 9.7 5.8 16.4 2.4e+02 1.3 16.4 2.4 1 1 0 1 1 1 0 Ribosomal protein L4/L1 family PDEase_I PF00233.19 KFP05754.1 - 6.1e-93 310.9 3.3 6.1e-93 310.9 3.3 1.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase PDE4_UCR PF18100.1 KFP05754.1 - 4.2e-39 133.8 0.6 1.8e-38 131.8 0.6 2.2 1 0 0 1 1 1 1 Phosphodiesterase 4 upstream conserved regions (UCR) DEP PF00610.21 KFP05755.1 - 1.2e-14 54.0 0.0 4.1e-14 52.4 0.0 1.9 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.27 KFP05755.1 - 2e-07 30.9 0.1 7e-07 29.2 0.1 1.9 1 0 0 1 1 1 1 RhoGAP domain ELO PF01151.18 KFP05756.1 - 3.7e-62 210.1 27.9 4.3e-62 209.9 27.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family WD40 PF00400.32 KFP05757.1 - 1.3e-22 79.6 11.6 8.4e-06 26.4 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP05757.1 - 5.2e-09 36.3 0.1 0.031 14.6 0.0 4.6 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP05757.1 - 0.01 14.5 2.0 3 6.4 0.0 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 DUF4763 PF15960.5 KFP05758.1 - 0.045 13.1 0.1 0.045 13.1 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) TLV_coat PF00429.19 KFP05758.1 - 0.059 12.0 0.2 0.067 11.9 0.2 1.0 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) Lectin_N PF03954.14 KFP05758.1 - 0.086 12.6 0.0 0.09 12.5 0.0 1.1 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain NDUFA12 PF05071.16 KFP05759.1 - 7.4e-05 23.5 3.7 7.6e-05 23.5 3.0 1.5 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 UPF0542 PF15086.6 KFP05760.1 - 1.6e-31 108.0 1.7 1.8e-31 107.8 1.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0542 TMEM100 PF16311.5 KFP05760.1 - 0.085 12.4 0.1 0.1 12.2 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 100 DUF4413 PF14372.6 KFP05761.1 - 0.097 13.1 0.1 0.32 11.4 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) SWIM PF04434.17 KFP05761.1 - 0.17 11.6 3.4 0.46 10.2 3.4 1.8 1 0 0 1 1 1 0 SWIM zinc finger Kinesin PF00225.23 KFP05763.1 - 7e-93 311.2 0.1 7e-93 311.2 0.1 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFP05763.1 - 7.4e-15 55.2 0.1 5.9e-14 52.2 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding UPF0242 PF06785.11 KFP05763.1 - 1.8 8.6 12.9 0.67 10.0 6.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CREPT PF16566.5 KFP05763.1 - 2.6 8.2 9.6 0.62 10.2 2.6 3.0 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Lipase PF00151.19 KFP05764.1 - 9.3e-121 403.2 0.0 1.1e-120 402.9 0.0 1.1 1 0 0 1 1 1 1 Lipase PLAT PF01477.23 KFP05764.1 - 2.8e-21 76.2 1.2 5.2e-21 75.4 1.2 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain Abhydrolase_6 PF12697.7 KFP05764.1 - 0.0003 21.5 0.1 0.00043 21.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFP05764.1 - 0.0014 18.4 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Sec7 PF01369.20 KFP05765.1 - 2.9e-44 150.9 0.4 4.9e-44 150.2 0.4 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KFP05765.1 - 8.7e-40 135.8 1.1 2.3e-39 134.4 0.7 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KFP05765.1 - 1.5e-14 54.4 0.2 3.7e-14 53.1 0.2 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFP05765.1 - 0.0011 19.4 0.7 0.005 17.2 0.7 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.10 KFP05765.1 - 0.033 14.5 0.3 0.078 13.3 0.3 1.6 1 0 0 1 1 1 0 Plant pleckstrin homology-like region RNA_pol_Rpb2_2 PF04561.14 KFP05765.1 - 0.085 12.5 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 YscJ_FliF PF01514.17 KFP05766.1 - 0.11 12.2 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family NIPSNAP PF07978.13 KFP05767.1 - 1.8e-52 175.8 0.8 1.7e-29 102.0 0.2 2.0 2 0 0 2 2 2 2 NIPSNAP ABC2_membrane_3 PF12698.7 KFP05768.1 - 9.1e-60 202.6 50.1 9.5e-47 159.8 23.0 3.4 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 KFP05768.1 - 2.4e-52 177.1 0.0 9.8e-29 100.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KFP05768.1 - 7.6e-19 68.6 0.1 2.6e-06 27.5 0.0 4.5 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 KFP05768.1 - 1.4e-05 25.7 0.0 0.021 15.6 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) AAA_23 PF13476.6 KFP05768.1 - 0.0053 17.3 4.0 0.028 14.9 0.3 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFP05768.1 - 0.016 14.9 1.2 0.57 10.0 0.3 3.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_15 PF13175.6 KFP05768.1 - 0.13 12.0 0.3 2.4 7.8 0.0 3.2 4 0 0 4 4 4 0 AAA ATPase domain RsgA_GTPase PF03193.16 KFP05768.1 - 0.19 11.6 0.2 8 6.3 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase Glyco_transf_8 PF01501.20 KFP05769.1 - 1.2e-17 64.4 0.1 5.9e-15 55.5 0.0 2.8 2 1 0 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KFP05769.1 - 0.0016 17.9 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 KFP05769.1 - 0.0078 16.2 0.1 0.015 15.2 0.1 1.5 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Bet_v_1 PF00407.19 KFP05769.1 - 0.067 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Pathogenesis-related protein Bet v I family SNF2_N PF00176.23 KFP05770.1 - 2.7e-82 276.3 0.1 3.8e-82 275.8 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KFP05770.1 - 1.1e-18 66.9 0.0 2.5e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KFP05770.1 - 5e-13 49.4 0.0 2.1e-12 47.3 0.0 2.1 3 0 0 3 3 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 KFP05770.1 - 1.9e-08 34.1 8.0 4.4e-08 32.9 8.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP05770.1 - 2.6e-08 33.6 10.0 7e-08 32.2 10.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP05770.1 - 4e-08 33.1 7.7 1.2e-07 31.6 7.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFP05770.1 - 7e-08 32.2 10.6 1.7e-07 31.0 10.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP05770.1 - 1.4e-06 28.5 9.8 1.4e-06 28.5 9.8 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KFP05770.1 - 5.5e-06 26.2 8.5 5.5e-06 26.2 8.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP05770.1 - 8.6e-06 25.5 10.0 2.3e-05 24.2 10.0 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFP05770.1 - 2.2e-05 24.5 10.7 4.9e-05 23.4 10.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING ResIII PF04851.15 KFP05770.1 - 0.00021 21.3 0.0 0.2 11.6 0.0 2.7 3 0 0 3 3 2 2 Type III restriction enzyme, res subunit zf-ANAPC11 PF12861.7 KFP05770.1 - 0.00029 20.8 1.7 0.00068 19.6 1.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KFP05770.1 - 0.00034 20.9 4.4 0.0011 19.2 4.4 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KFP05770.1 - 0.024 14.5 4.4 0.13 12.1 4.4 2.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 KFP05770.1 - 0.025 14.4 5.2 0.071 12.9 5.2 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KFP05770.1 - 0.037 13.8 2.5 0.085 12.7 2.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain AAA_34 PF13872.6 KFP05770.1 - 0.14 11.0 0.0 13 4.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 zf-RING_11 PF17123.5 KFP05770.1 - 2.1 8.2 8.3 5.7 6.8 8.3 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_10 PF16685.5 KFP05770.1 - 9.3 6.5 9.7 30 4.9 9.7 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 Tubulin PF00091.25 KFP05772.1 - 1.9e-66 224.1 0.0 2.4e-66 223.7 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFP05772.1 - 7.4e-52 174.8 0.0 1.6e-51 173.7 0.0 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFP05772.1 - 0.0025 17.5 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain HPS3_C PF14763.6 KFP05773.1 - 1.5e-168 560.6 4.7 2.8e-168 559.7 4.7 1.4 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3, C-terminal HPS3_Mid PF14762.6 KFP05773.1 - 3e-165 549.7 6.2 5.1e-165 548.9 6.2 1.4 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3, middle region HPS3_N PF14761.6 KFP05773.1 - 1.6e-54 184.7 0.0 4e-54 183.4 0.0 1.7 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3 Cu-oxidase_2 PF07731.14 KFP05774.1 - 1.6e-28 99.2 19.1 7.3e-15 54.9 7.3 6.6 6 2 0 6 6 6 5 Multicopper oxidase Cu-oxidase_3 PF07732.15 KFP05774.1 - 6.3e-28 97.2 7.9 1.3e-08 34.9 0.0 5.9 5 1 0 5 5 5 4 Multicopper oxidase L6_membrane PF05805.12 KFP05775.1 - 8.7e-55 185.3 16.0 9.7e-55 185.1 16.0 1.0 1 0 0 1 1 1 1 L6 membrane protein Rep_fac-A_C PF08646.10 KFP05775.1 - 0.054 13.2 0.2 0.42 10.3 0.1 2.0 2 0 0 2 2 2 0 Replication factor-A C terminal domain DUF2231 PF09990.9 KFP05775.1 - 3.7 8.0 6.5 0.87 10.1 0.2 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) L6_membrane PF05805.12 KFP05776.1 - 5.7e-68 228.3 15.7 6.4e-68 228.1 15.7 1.0 1 0 0 1 1 1 1 L6 membrane protein Yip1 PF04893.17 KFP05776.1 - 0.0011 18.7 1.6 0.0011 18.7 1.6 1.8 2 0 0 2 2 2 1 Yip1 domain L6_membrane PF05805.12 KFP05777.1 - 2.7e-75 252.1 15.4 3.1e-75 251.9 15.4 1.0 1 0 0 1 1 1 1 L6 membrane protein ABC2_membrane_3 PF12698.7 KFP05777.1 - 0.05 12.7 2.0 0.099 11.7 2.0 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein COMM_domain PF07258.14 KFP05779.1 - 1.6e-17 63.4 0.7 1.6e-17 63.4 0.7 1.7 2 0 0 2 2 2 1 COMM domain XPC-binding PF09280.11 KFP05779.1 - 0.095 12.4 2.8 0.1 12.4 0.8 2.0 2 0 0 2 2 2 0 XPC-binding domain HTH_1 PF00126.27 KFP05779.1 - 0.11 12.5 0.4 0.48 10.4 0.1 2.0 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family zf-RING_2 PF13639.6 KFP05780.1 - 3.2e-13 49.8 8.3 5.4e-13 49.1 8.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFP05780.1 - 8.8e-12 44.6 3.9 8.8e-12 44.6 3.9 2.3 2 0 0 2 2 2 1 RING-like zinc finger PA PF02225.22 KFP05780.1 - 3.2e-09 36.7 0.0 7.2e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.6 KFP05780.1 - 1.1e-08 34.8 8.9 1.9e-08 34.0 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP05780.1 - 1.8e-08 34.1 8.4 3e-08 33.4 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP05780.1 - 3.4e-06 26.9 6.9 5.4e-06 26.3 6.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFP05780.1 - 4e-06 26.6 6.3 6.6e-06 25.9 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFP05780.1 - 1.4e-05 25.3 10.9 7.3e-05 23.0 10.9 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFP05780.1 - 6.2e-05 22.9 4.4 0.00014 21.8 2.0 2.3 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFP05780.1 - 0.0015 18.4 6.7 0.0028 17.5 6.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Neur_chan_memb PF02932.16 KFP05780.1 - 0.0028 17.8 0.0 0.0042 17.2 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region zf-ANAPC11 PF12861.7 KFP05780.1 - 0.0031 17.5 6.2 0.0093 16.0 6.2 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger SPX PF03105.19 KFP05780.1 - 0.04 13.8 1.5 0.053 13.4 1.5 1.1 1 0 0 1 1 1 0 SPX domain Baculo_11_kDa PF06143.11 KFP05780.1 - 0.056 13.0 0.6 2 8.0 0.1 3.0 3 0 0 3 3 3 0 Baculovirus 11 kDa family DNA_ligase_ZBD PF03119.16 KFP05780.1 - 0.079 13.0 0.4 0.17 11.9 0.4 1.6 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain FeoB_associated PF12669.7 KFP05780.1 - 0.093 13.1 1.8 0.29 11.6 1.8 1.8 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein PHD PF00628.29 KFP05780.1 - 0.13 12.2 8.6 0.23 11.4 8.6 1.4 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 KFP05780.1 - 0.16 11.6 5.1 0.32 10.6 5.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KFP05780.1 - 0.32 10.8 8.7 0.64 9.9 8.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain STAC2_u1 PF16664.5 KFP05780.1 - 0.8 10.2 6.2 1.7 9.1 6.2 1.5 1 1 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 RINGv PF12906.7 KFP05780.1 - 1 9.5 7.4 2.2 8.5 7.4 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 KFP05780.1 - 4.8 7.3 9.3 15 5.8 9.3 1.8 1 1 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 KFP05780.1 - 7.1 6.9 9.0 57 4.0 9.0 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Profilin PF00235.19 KFP05781.1 - 4.4e-13 49.6 0.0 4.8e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Profilin TSC22 PF01166.18 KFP05782.1 - 3.2e-27 94.6 5.5 3.8e-27 94.4 5.5 1.1 1 0 0 1 1 1 1 TSC-22/dip/bun family K-box PF01486.17 KFP05782.1 - 0.0018 18.4 1.0 0.0024 18.0 1.0 1.3 1 0 0 1 1 1 1 K-box region YabA PF06156.13 KFP05782.1 - 0.002 18.7 3.1 0.0024 18.5 3.1 1.1 1 0 0 1 1 1 1 Initiation control protein YabA DivIC PF04977.15 KFP05782.1 - 0.0055 16.4 3.1 0.0061 16.3 2.6 1.4 1 1 0 1 1 1 1 Septum formation initiator ZapB PF06005.12 KFP05782.1 - 0.091 13.2 6.7 0.13 12.7 6.7 1.5 1 1 0 1 1 1 0 Cell division protein ZapB eIF2A PF08662.11 KFP05783.1 - 2.7e-79 265.6 1.8 7.4e-77 257.6 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KFP05783.1 - 0.0012 19.1 2.4 2 8.8 0.0 4.5 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Rdx PF10262.9 KFP05784.1 - 3.2e-11 43.2 0.0 3.9e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Rdx family FAM194 PF14977.6 KFP05785.1 - 1.2e-51 175.0 0.0 1.4e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 FAM194 protein Sina PF03145.16 KFP05786.1 - 8.8e-84 280.4 0.1 8.8e-84 280.4 0.1 1.3 2 0 0 2 2 2 1 Seven in absentia protein family zf_C2H2_6 PF18450.1 KFP05786.1 - 0.26 11.0 3.0 0.77 9.5 3.0 1.9 1 0 0 1 1 1 0 Zinc Finger domain zf-C3HC4_2 PF13923.6 KFP05786.1 - 0.37 10.7 15.4 0.076 12.9 11.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP05786.1 - 0.69 9.8 9.9 2.4 8.1 9.9 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP05786.1 - 0.82 9.6 12.5 11 6.0 11.7 2.8 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-TRAF_2 PF15965.5 KFP05786.1 - 2.8 8.5 12.0 0.18 12.3 5.5 2.1 1 1 0 1 1 1 0 TRAF-like zinc-finger zf-C3HC4_4 PF15227.6 KFP05786.1 - 6.4 7.0 14.4 0.46 10.7 8.3 2.3 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF4205 PF13898.6 KFP05787.1 - 1.2e-30 106.6 0.0 1.3e-30 106.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) Prot_inhib_II PF02428.15 KFP05787.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Potato type II proteinase inhibitor family Synaptobrevin PF00957.21 KFP05788.1 - 0.23 11.3 1.6 0.43 10.4 0.0 2.1 2 0 0 2 2 2 0 Synaptobrevin Med12-LCEWAV PF12145.8 KFP05789.1 - 2.6e-178 593.8 0.1 4e-178 593.1 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain Med12 PF09497.10 KFP05789.1 - 2.6e-14 53.3 0.2 6e-14 52.1 0.2 1.6 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 CNOT1_HEAT PF16418.5 KFP05789.1 - 0.047 13.8 1.5 5.7 7.0 0.1 3.8 3 0 0 3 3 3 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Cortex-I_coil PF09304.10 KFP05789.1 - 7.6 6.8 7.2 1.3 9.3 2.2 2.3 2 0 0 2 2 2 0 Cortexillin I, coiled coil 7tm_1 PF00001.21 KFP05790.1 - 1e-29 103.7 23.2 1.2e-29 103.5 23.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ni_hydr_CYTB PF01292.20 KFP05790.1 - 0.075 12.6 4.7 0.053 13.1 1.0 2.4 1 1 2 3 3 3 0 Prokaryotic cytochrome b561 DUF948 PF06103.11 KFP05790.1 - 0.098 12.9 0.0 0.49 10.7 0.0 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) OAD_gamma PF04277.13 KFP05790.1 - 0.31 11.6 0.3 0.31 11.6 0.3 2.7 3 1 1 4 4 4 0 Oxaloacetate decarboxylase, gamma chain YtpI PF14007.6 KFP05790.1 - 0.61 10.3 0.1 0.61 10.3 0.1 4.0 3 1 1 4 4 4 0 YtpI-like protein DUF4131 PF13567.6 KFP05790.1 - 4.8 6.8 5.7 0.62 9.7 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) 7tm_1 PF00001.21 KFP05791.1 - 1.5e-37 129.4 21.5 1.7e-37 129.2 21.5 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP05791.1 - 3e-05 23.8 20.3 3e-05 23.8 20.3 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Alg14 PF08660.11 KFP05791.1 - 0.021 14.8 1.3 0.032 14.2 0.6 1.6 1 1 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like Phage_holin_4_2 PF04020.13 KFP05791.1 - 0.57 10.9 10.4 5.7 7.7 4.3 3.3 2 1 0 3 3 3 0 Mycobacterial 4 TMS phage holin, superfamily IV Sigma_reg_N PF13800.6 KFP05791.1 - 6.6 7.1 8.5 10 6.5 0.1 3.1 2 1 1 3 3 3 0 Sigma factor regulator N-terminal 7tm_1 PF00001.21 KFP05792.1 - 2.3e-33 115.6 19.1 2.7e-33 115.4 19.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFP05792.1 - 8.1e-05 22.1 15.4 0.00012 21.6 15.4 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv DUF373 PF04123.13 KFP05792.1 - 0.85 9.0 5.6 0.45 9.9 3.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF373) 7tm_1 PF00001.21 KFP05793.1 - 6.4e-36 124.0 20.9 7.4e-36 123.8 20.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2976 PF11190.8 KFP05793.1 - 0.006 16.4 1.3 0.023 14.5 1.3 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2976) DUF373 PF04123.13 KFP05793.1 - 4.6 6.6 15.6 3.4 7.0 13.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Ig_3 PF13927.6 KFP05794.1 - 3.9e-45 152.3 0.0 2.4e-11 44.1 0.0 4.2 4 0 0 4 4 4 4 Immunoglobulin domain I-set PF07679.16 KFP05794.1 - 2e-44 149.6 0.0 8.6e-11 41.8 0.0 4.2 4 0 0 4 4 4 4 Immunoglobulin I-set domain ig PF00047.25 KFP05794.1 - 6e-32 109.7 0.0 4e-09 36.5 0.0 4.2 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFP05794.1 - 1.3e-25 89.5 0.0 4.9e-06 26.8 0.0 4.8 4 1 0 4 4 4 4 Immunoglobulin domain V-set PF07686.17 KFP05794.1 - 1.9e-15 57.0 0.0 0.0061 16.7 0.0 5.3 4 1 0 4 4 4 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP05794.1 - 3.6e-08 33.4 0.3 0.17 11.9 0.0 4.3 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFP05794.1 - 3.2e-06 26.6 0.0 0.6 9.7 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain Receptor_2B4 PF11465.8 KFP05794.1 - 0.062 13.5 0.0 12 6.2 0.0 2.7 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 DUF5607 PF18355.1 KFP05794.1 - 0.15 12.5 0.0 21 5.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5607) LRR_8 PF13855.6 KFP05795.1 - 1.5e-30 104.7 18.3 2.8e-13 49.4 1.1 4.0 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFP05795.1 - 4.3e-14 52.4 11.4 0.00023 21.4 0.4 4.1 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP05795.1 - 1.2e-08 35.0 0.3 0.00092 19.2 0.0 2.5 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFP05795.1 - 2.6e-05 24.2 10.5 14 6.7 0.1 6.6 5 1 2 7 7 7 3 Leucine Rich Repeat LRR_9 PF14580.6 KFP05795.1 - 0.00015 21.3 3.1 0.014 14.9 0.6 2.9 1 1 2 3 3 3 2 Leucine-rich repeat LRR_3 PF07725.12 KFP05795.1 - 0.19 11.6 5.6 13 5.8 0.1 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat 7tm_1 PF00001.21 KFP05796.1 - 1.7e-36 125.9 14.1 2.2e-36 125.5 14.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP05796.1 - 0.15 11.7 14.8 0.34 10.6 14.8 1.5 1 1 0 1 1 1 0 Olfactory receptor Wzy_C_2 PF11846.8 KFP05796.1 - 7.5 6.4 7.2 3.5 7.5 0.5 2.2 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal zf-CCCH PF00642.24 KFP05797.1 - 3.9e-10 39.4 25.1 0.00024 20.9 1.1 4.9 4 1 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KFP05797.1 - 5.5e-09 36.2 6.1 4.7e-05 23.6 0.2 2.4 2 0 0 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 KFP05797.1 - 2.9e-05 23.7 27.7 0.00035 20.3 2.7 4.7 4 1 0 4 4 4 3 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KFP05797.1 - 5.5e-05 23.5 27.5 0.24 12.0 1.6 4.4 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KFP05797.1 - 0.0012 19.5 19.2 1.4 9.6 0.3 4.4 2 2 2 4 4 4 4 Torus domain zf_CCCH_4 PF18345.1 KFP05797.1 - 0.0048 16.9 33.5 0.051 13.6 4.6 6.7 4 4 0 4 4 4 2 Zinc finger domain DUF1936 PF09151.10 KFP05797.1 - 6.3 6.8 10.4 5.8 6.9 0.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1936) 7tm_1 PF00001.21 KFP05798.1 - 5.8e-43 147.1 19.6 8.8e-43 146.5 19.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pet100 PF09803.9 KFP05798.1 - 0.17 12.4 0.9 0.46 11.0 0.9 1.7 1 0 0 1 1 1 0 Pet100 7TM_GPCR_Srx PF10328.9 KFP05798.1 - 2.1 7.9 24.9 2.9 7.5 20.9 2.3 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx RhoGEF PF00621.20 KFP05799.1 - 9.3e-38 130.3 5.4 1.8e-37 129.3 5.4 1.5 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.6 KFP05799.1 - 3.2e-12 46.1 0.1 6.4e-12 45.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP05799.1 - 4.6e-12 45.4 0.0 1.4e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP05799.1 - 7.7e-10 38.3 0.0 2e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 KFP05799.1 - 4.6e-07 30.3 0.8 2e-06 28.3 0.0 2.3 2 1 0 2 2 2 1 PH domain IQ_SEC7_PH PF16453.5 KFP05799.1 - 0.00057 19.9 1.5 0.0022 18.0 0.0 2.5 2 1 0 2 2 2 1 PH domain PH_13 PF16652.5 KFP05799.1 - 0.028 14.2 2.2 0.47 10.2 0.5 3.3 2 1 0 2 2 2 0 Pleckstrin homology domain Suppressor_P21 PF11479.8 KFP05799.1 - 0.043 14.0 1.0 0.28 11.4 0.2 2.6 2 0 0 2 2 2 0 RNA silencing suppressor P21 C-terminal domain HA2 PF04408.23 KFP05800.1 - 1.1e-20 74.0 0.0 2.8e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFP05800.1 - 2.1e-17 63.3 0.0 4.9e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFP05800.1 - 1.3e-16 60.9 0.1 3.3e-16 59.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFP05800.1 - 2.8e-14 53.3 0.1 8.2e-14 51.8 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFP05800.1 - 2.6e-05 24.5 0.1 7.2e-05 23.1 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFP05800.1 - 0.00096 19.5 0.5 0.0037 17.6 0.0 2.2 3 0 0 3 3 2 1 AAA domain ATPase PF06745.13 KFP05800.1 - 0.0016 17.8 0.0 0.0046 16.3 0.0 1.7 1 0 0 1 1 1 1 KaiC AAA_23 PF13476.6 KFP05800.1 - 0.021 15.3 0.1 0.021 15.3 0.1 2.4 2 1 1 3 3 3 0 AAA domain AAA_14 PF13173.6 KFP05800.1 - 0.033 14.2 0.5 0.74 9.9 0.5 2.8 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KFP05800.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein RsgA_GTPase PF03193.16 KFP05800.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase SmpA_OmlA PF04355.13 KFP05800.1 - 0.15 11.9 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 SmpA / OmlA family NACHT PF05729.12 KFP05800.1 - 0.17 11.8 0.3 0.8 9.6 0.3 2.4 1 1 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KFP05800.1 - 0.21 12.0 0.5 0.96 9.8 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.27 KFP05800.1 - 0.27 11.7 0.8 0.96 10.0 0.1 2.3 2 1 0 2 2 2 0 ABC transporter 7tm_1 PF00001.21 KFP05801.1 - 2.4e-08 33.6 14.0 2.4e-08 33.6 14.0 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Peptidase_M13_N PF05649.13 KFP05802.1 - 1.4e-118 397.0 1.9 2.1e-118 396.4 1.9 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFP05802.1 - 4.5e-72 242.0 0.2 7.8e-72 241.2 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M13 Acatn PF13000.7 KFP05804.1 - 4.8e-119 398.4 16.1 1.1e-70 238.7 7.0 3.2 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 GATase PF00117.28 KFP05805.1 - 5.8e-40 137.1 0.0 2.6e-39 135.0 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 KFP05805.1 - 2.2e-18 66.1 0.0 6e-11 42.3 0.0 3.1 2 1 0 2 2 2 2 GMP synthase C terminal domain NAD_synthase PF02540.17 KFP05805.1 - 6e-13 48.5 0.1 4.6e-09 35.7 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KFP05805.1 - 3.9e-12 46.4 0.1 1.5e-11 44.4 0.1 2.0 1 1 0 1 1 1 1 Peptidase C26 QueC PF06508.13 KFP05805.1 - 3.1e-08 33.4 0.1 3.1e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KFP05805.1 - 4.1e-06 25.8 0.0 1.5e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.21 KFP05805.1 - 0.00027 20.7 0.0 0.00044 20.0 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 KFP05805.1 - 0.00029 20.7 0.0 0.00057 19.7 0.0 1.5 1 0 0 1 1 1 1 PP-loop family ThiI PF02568.14 KFP05805.1 - 0.0007 19.2 0.1 0.0018 17.9 0.1 1.7 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 KFP05805.1 - 0.0011 19.0 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.19 KFP05805.1 - 0.0021 17.4 0.0 0.0034 16.7 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase rve PF00665.26 KFP05805.1 - 0.078 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain Aldo_ket_red PF00248.21 KFP05806.1 - 5.4e-30 104.6 0.0 7.6e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KFP05807.1 - 4.3e-16 59.0 0.0 5.2e-16 58.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2685 PF10886.8 KFP05807.1 - 0.019 15.2 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2685) Ribonuc_red_2_N PF08471.10 KFP05807.1 - 0.1 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase MRF_C1 PF13887.6 KFP05807.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 TRAP-gamma PF07074.12 KFP05808.1 - 7.8e-84 279.4 7.8 8.8e-84 279.2 7.8 1.0 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) Renin_r PF07850.14 KFP05808.1 - 0.0088 16.6 2.6 0.045 14.3 0.3 2.1 2 0 0 2 2 2 1 Renin receptor-like protein SPC25 PF06703.11 KFP05808.1 - 0.22 11.3 4.1 0.13 12.0 2.3 1.6 1 1 1 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) PARP PF00644.20 KFP05809.1 - 1.2e-34 119.6 4.5 1.7e-33 115.9 4.5 1.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Wtap PF17098.5 KFP05810.1 - 0.0086 16.0 22.9 0.011 15.6 15.4 3.0 1 1 1 2 2 2 1 WTAP/Mum2p family OmpH PF03938.14 KFP05810.1 - 0.011 16.1 24.7 0.021 15.2 8.6 2.6 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) IFT57 PF10498.9 KFP05810.1 - 0.013 14.5 25.8 0.097 11.6 10.2 2.3 1 1 0 2 2 2 0 Intra-flagellar transport protein 57 GAS PF13851.6 KFP05810.1 - 0.056 12.8 33.9 0.6 9.4 15.0 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding UPF0231 PF06062.11 KFP05810.1 - 0.17 12.2 11.2 3.2 8.0 0.5 3.4 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0231) APG6_N PF17675.1 KFP05810.1 - 0.17 12.4 30.7 0.57 10.7 9.6 2.7 2 1 0 2 2 2 0 Apg6 coiled-coil region HMMR_N PF15905.5 KFP05810.1 - 0.2 11.1 33.9 0.18 11.2 20.6 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal KASH_CCD PF14662.6 KFP05810.1 - 0.32 10.8 31.2 0.29 11.0 6.2 3.2 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 KFP05810.1 - 0.57 10.2 34.0 0.48 10.4 12.6 3.0 2 2 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EzrA PF06160.12 KFP05810.1 - 0.93 7.6 24.3 0.22 9.6 9.8 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF1664 PF07889.12 KFP05810.1 - 0.94 9.5 15.5 1.1 9.4 1.6 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 KFP05810.1 - 1.1 9.8 10.6 19 5.8 0.0 4.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 KFP05810.1 - 1.1 8.0 31.7 0.86 8.4 11.4 2.4 1 1 0 2 2 2 0 Spc7 kinetochore protein Fez1 PF06818.15 KFP05810.1 - 1.7 9.1 25.6 2.8 8.3 9.6 2.5 1 1 1 2 2 2 0 Fez1 T3SSipB PF16535.5 KFP05810.1 - 1.7 9.1 15.0 88 3.5 14.2 2.4 1 1 0 1 1 1 0 Type III cell invasion protein SipB Bacillus_HBL PF05791.11 KFP05810.1 - 1.9 8.3 16.4 0.053 13.3 2.0 2.7 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) HOOK PF05622.12 KFP05810.1 - 2.2 6.3 29.6 6.9 4.7 29.6 1.7 1 1 0 1 1 1 0 HOOK protein DUF5082 PF16888.5 KFP05810.1 - 2.8 8.3 18.2 2 8.7 3.8 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF5082) DUF2203 PF09969.9 KFP05810.1 - 3.4 8.4 16.6 0.71 10.6 3.7 3.2 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF932 PF06067.11 KFP05810.1 - 4.8 6.9 8.3 0.16 11.7 0.7 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF932) Sec34 PF04136.15 KFP05810.1 - 5.9 6.8 24.0 4.3 7.2 7.1 3.3 1 1 0 3 3 3 0 Sec34-like family GAS PF13851.6 KFP05811.1 - 1.8 7.9 62.7 1.7 7.9 9.1 3.6 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding Cyclin_N PF00134.23 KFP05812.1 - 1.4e-11 44.3 0.3 8.2e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP05812.1 - 9.7e-06 25.7 0.1 9.7e-06 25.7 0.1 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.19 KFP05812.1 - 0.00038 20.5 0.4 0.24 11.5 0.0 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 KFP05812.1 - 0.0058 17.0 0.1 0.013 15.9 0.1 1.8 1 1 0 1 1 1 1 Cyclin C-terminal domain PH PF00169.29 KFP05813.1 - 4.7e-12 46.4 1.4 8.6e-12 45.5 0.5 1.9 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KFP05813.1 - 0.0031 17.9 3.1 0.0073 16.7 2.2 2.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 KFP05813.1 - 0.084 13.2 0.5 0.45 10.9 0.5 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain Homeodomain PF00046.29 KFP05814.1 - 2.8e-06 27.1 9.2 0.0048 16.7 3.5 2.4 2 0 0 2 2 2 2 Homeodomain Mlf1IP PF10248.9 KFP05816.1 - 5e-75 251.2 10.3 5.8e-75 251.0 10.3 1.0 1 0 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein GTP_EFTU PF00009.27 KFP05817.1 - 2.7e-64 216.3 0.0 4e-64 215.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KFP05817.1 - 1.1e-34 118.8 0.2 3.6e-34 117.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 KFP05817.1 - 2.3e-31 107.7 0.0 6.1e-31 106.3 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KFP05817.1 - 5.7e-25 87.2 0.1 1.5e-24 85.9 0.1 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFP05817.1 - 3e-16 59.6 0.1 1.1e-15 57.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KFP05817.1 - 1.1e-07 31.7 0.0 7.2e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 KFP05817.1 - 0.0012 18.9 0.1 0.0026 17.8 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KFP05817.1 - 0.019 14.3 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family SRPRB PF09439.10 KFP05817.1 - 0.14 11.6 0.0 0.46 9.9 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AvrPtoB_bdg PF16847.5 KFP05817.1 - 0.15 12.6 0.0 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain Latexin PF06907.12 KFP05818.1 - 9.4e-54 182.2 0.0 1e-53 182.1 0.0 1.0 1 0 0 1 1 1 1 Latexin Latexin PF06907.12 KFP05819.1 - 9.3e-68 228.0 0.1 1.1e-67 227.8 0.1 1.0 1 0 0 1 1 1 1 Latexin IQCJ-SCHIP1 PF15157.6 KFP05820.1 - 4.3e-50 169.5 1.9 4.9e-50 169.3 1.9 1.0 1 0 0 1 1 1 1 Fusion protein IQCJ-SCHIP1 with IQ-like motif Plasmid_RAQPRD PF09686.10 KFP05820.1 - 0.0046 17.1 0.3 0.0065 16.7 0.3 1.1 1 0 0 1 1 1 1 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF5314 PF17241.2 KFP05820.1 - 0.039 13.6 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5314) IQ PF00612.27 KFP05820.1 - 0.049 13.4 0.2 0.1 12.5 0.2 1.5 1 0 0 1 1 1 0 IQ calmodulin-binding motif PSK_trans_fac PF07704.11 KFP05820.1 - 0.11 13.2 0.1 5.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor SCHIP-1 PF10148.9 KFP05821.1 - 1.1e-89 300.1 11.2 1.2e-89 300.0 11.2 1.0 1 0 0 1 1 1 1 Schwannomin-interacting protein 1 FEZ PF07763.13 KFP05821.1 - 0.00012 21.9 7.9 0.00023 21.0 7.9 1.5 1 1 0 1 1 1 1 FEZ-like protein DUF5102 PF17104.5 KFP05821.1 - 0.0062 16.6 6.4 0.008 16.3 6.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) EURL PF06937.11 KFP05821.1 - 0.15 11.5 6.6 0.33 10.3 3.2 2.0 1 1 1 2 2 2 0 EURL protein ABC_tran_Xtn PF12848.7 KFP05821.1 - 4.3 7.4 7.0 2.7 8.1 3.9 1.9 2 0 0 2 2 2 0 ABC transporter FIIND PF13553.6 KFP05822.1 - 1.1e-25 90.5 0.0 1.2e-25 90.4 0.0 1.0 1 0 0 1 1 1 1 Function to find zf-RING_UBOX PF13445.6 KFP05823.1 - 1.9e-11 43.8 4.4 1.9e-11 43.8 4.4 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-B_box PF00643.24 KFP05823.1 - 3.6e-08 33.4 2.7 3.6e-08 33.4 2.7 3.3 4 0 0 4 4 4 1 B-box zinc finger zf-C3HC4_2 PF13923.6 KFP05823.1 - 6.5e-08 32.3 1.6 6.5e-08 32.3 1.6 2.9 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP05823.1 - 1.7e-07 31.0 3.8 1.7e-07 31.0 3.8 2.8 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP05823.1 - 3.3e-07 30.5 6.3 3.3e-07 30.5 6.3 2.5 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KFP05823.1 - 8.1e-07 28.9 3.7 8.1e-07 28.9 3.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFP05823.1 - 6e-05 23.1 7.2 6e-05 23.1 7.2 3.1 2 2 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KFP05823.1 - 0.00016 21.4 8.0 0.00016 21.4 8.0 2.9 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP05823.1 - 0.00024 20.9 4.3 0.00024 20.9 4.3 2.8 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KFP05823.1 - 0.00054 19.8 2.0 0.00054 19.8 2.0 2.1 3 0 0 3 3 2 1 zf-RING of BARD1-type protein U-box PF04564.15 KFP05823.1 - 0.0052 16.9 0.0 0.15 12.2 0.0 2.5 2 0 0 2 2 2 1 U-box domain Cob_adeno_trans PF01923.18 KFP05823.1 - 0.12 12.5 0.3 0.23 11.6 0.3 1.4 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF349 PF03993.12 KFP05823.1 - 0.19 12.1 4.2 0.08 13.2 1.2 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) AAA_23 PF13476.6 KFP05823.1 - 0.25 11.8 6.5 0.32 11.4 6.5 1.1 1 0 0 1 1 1 0 AAA domain FAM184 PF15665.5 KFP05823.1 - 0.29 10.9 9.2 0.094 12.5 5.6 1.9 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B zf-RING_11 PF17123.5 KFP05823.1 - 0.32 10.8 10.5 0.065 13.0 5.7 2.4 2 0 0 2 2 2 0 RING-like zinc finger DUF2046 PF09755.9 KFP05823.1 - 3.8 6.7 15.9 0.063 12.5 3.7 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) HalX PF08663.10 KFP05823.1 - 5.4 7.4 7.8 0.86 10.0 2.3 2.3 2 1 1 3 3 3 0 HalX domain Arm PF00514.23 KFP05824.1 - 3.7e-92 299.9 18.9 2.9e-13 49.3 0.2 9.2 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 KFP05824.1 - 3.3e-25 87.4 3.1 2.6e-23 81.3 3.2 2.6 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 KFP05824.1 - 2.2e-22 79.1 0.6 4.4e-09 36.6 0.1 5.8 5 0 0 5 5 5 3 HEAT-like repeat HEAT_2 PF13646.6 KFP05824.1 - 3.9e-19 68.8 0.5 5.5e-06 26.7 0.0 6.6 2 2 4 8 8 8 4 HEAT repeats HEAT PF02985.22 KFP05824.1 - 4.4e-17 60.7 4.7 0.0034 17.5 0.0 6.8 7 0 0 7 7 7 4 HEAT repeat IBB PF01749.20 KFP05824.1 - 2.1e-16 60.1 2.7 5.8e-16 58.7 2.7 1.8 1 0 0 1 1 1 1 Importin beta binding domain Adaptin_N PF01602.20 KFP05824.1 - 1.2e-07 30.8 1.7 1e-06 27.6 1.7 2.3 1 1 0 1 1 1 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 KFP05824.1 - 4e-07 30.2 1.0 0.1 12.7 0.1 4.4 4 1 1 5 5 5 3 V-ATPase subunit H V-ATPase_H_N PF03224.14 KFP05824.1 - 1.2e-05 24.8 1.5 0.00052 19.4 0.4 2.6 1 1 0 2 2 2 1 V-ATPase subunit H Cnd1 PF12717.7 KFP05824.1 - 2.4e-05 24.4 1.3 0.07 13.2 0.1 3.3 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Arm_2 PF04826.13 KFP05824.1 - 8.1e-05 22.2 1.2 0.16 11.4 0.3 3.5 2 1 2 4 4 4 2 Armadillo-like Atx10homo_assoc PF09759.9 KFP05824.1 - 0.0013 18.7 1.5 1.6 8.8 0.0 4.8 3 1 2 5 5 5 1 Spinocerebellar ataxia type 10 protein domain DRIM PF07539.12 KFP05824.1 - 0.0048 15.3 0.8 0.78 8.0 0.1 2.4 1 1 1 2 2 2 2 Down-regulated in metastasis RasGEF_N_2 PF14663.6 KFP05824.1 - 0.012 16.0 0.5 14 6.1 0.0 3.9 3 2 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Mo25 PF08569.11 KFP05824.1 - 0.043 13.2 0.1 0.12 11.7 0.1 1.7 1 1 0 1 1 1 0 Mo25-like MMS19_N PF14500.6 KFP05824.1 - 0.12 11.9 0.0 0.9 9.1 0.0 2.3 1 1 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II CTNNBL PF08216.11 KFP05824.1 - 0.14 12.4 5.6 6.9 6.9 0.1 4.2 5 1 0 5 5 5 0 Catenin-beta-like, Arm-motif containing nuclear Arf PF00025.21 KFP05825.1 - 5.7e-59 198.5 0.0 6.3e-59 198.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KFP05825.1 - 1.2e-15 57.6 2.9 2.3e-12 46.8 0.6 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KFP05825.1 - 1.9e-15 57.1 0.1 2.6e-15 56.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP05825.1 - 2.9e-15 56.2 0.0 3.3e-15 56.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KFP05825.1 - 3.5e-09 36.4 0.1 4.3e-09 36.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFP05825.1 - 3.6e-09 36.3 0.0 4.5e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFP05825.1 - 1.4e-06 28.4 0.0 3.6e-06 27.0 0.0 1.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP05825.1 - 0.00013 21.6 0.0 0.00042 19.9 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KFP05825.1 - 0.048 12.6 0.0 1.3 7.9 0.0 2.6 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB P3A PF08727.11 KFP05825.1 - 0.084 12.3 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Poliovirus 3A protein like PP2C PF00481.21 KFP05826.1 - 4.5e-52 177.2 0.0 5.1e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFP05826.1 - 2.5e-08 33.8 0.0 9.1e-08 32.0 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KFP05826.1 - 0.00063 19.7 0.0 0.085 12.8 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Trypsin PF00089.26 KFP05827.1 - 1.2e-69 234.5 0.0 1.3e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFP05827.1 - 5.1e-10 39.7 0.1 8.7e-10 39.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 KFP05827.1 - 0.0002 22.3 0.0 0.00031 21.7 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Lectin_C PF00059.21 KFP05828.1 - 7.3e-14 52.4 0.1 1.5e-13 51.4 0.1 1.6 1 0 0 1 1 1 1 Lectin C-type domain DUF3377 PF11857.8 KFP05828.1 - 0.16 11.9 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) EURL PF06937.11 KFP05829.1 - 3.2e-160 532.1 5.6 3.6e-160 531.9 5.6 1.0 1 0 0 1 1 1 1 EURL protein XRCC4 PF06632.12 KFP05829.1 - 0.0079 15.1 0.9 0.013 14.3 0.9 1.3 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 APG6_N PF17675.1 KFP05829.1 - 0.0089 16.6 1.6 0.025 15.1 1.6 1.7 1 0 0 1 1 1 1 Apg6 coiled-coil region Fzo_mitofusin PF04799.13 KFP05829.1 - 0.019 14.5 0.4 0.036 13.6 0.4 1.4 1 0 0 1 1 1 0 fzo-like conserved region Med21 PF11221.8 KFP05829.1 - 0.18 12.1 3.1 6.1 7.1 1.4 2.3 2 0 0 2 2 2 0 Subunit 21 of Mediator complex V-set PF07686.17 KFP05830.1 - 1.8e-23 82.8 0.8 9.9e-19 67.5 0.0 3.1 2 1 1 3 3 3 2 Immunoglobulin V-set domain I-set PF07679.16 KFP05830.1 - 2.9e-17 62.5 0.0 3.8e-08 33.3 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP05830.1 - 1.5e-16 60.8 0.1 5.5e-09 36.5 0.1 2.8 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP05830.1 - 1.7e-14 53.9 0.7 1.3e-08 35.0 0.1 3.2 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP05830.1 - 3.9e-14 52.6 0.0 2.2e-06 27.7 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin domain Ig_4 PF16680.5 KFP05830.1 - 2e-05 24.8 0.3 0.045 14.0 0.2 2.9 2 1 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 KFP05830.1 - 4e-05 23.6 0.0 0.059 13.4 0.0 2.9 3 0 0 3 3 3 2 C17orf99 Ig domain Ig_5 PF16681.5 KFP05830.1 - 5e-05 23.6 0.1 0.024 15.0 0.1 3.0 3 0 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain FAM163 PF15069.6 KFP05830.1 - 0.00035 21.1 0.0 0.00065 20.2 0.0 1.4 1 0 0 1 1 1 1 FAM163 family Ig_6 PF18452.1 KFP05830.1 - 0.0012 18.4 0.0 0.15 11.6 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain Adeno_E3_CR2 PF02439.15 KFP05830.1 - 0.0012 18.5 0.5 0.0026 17.5 0.5 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 KFP05830.1 - 0.0035 18.2 0.0 0.0068 17.3 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain V-set_CD47 PF08204.11 KFP05830.1 - 0.0053 16.7 0.0 1.4 8.9 0.0 2.5 2 1 0 2 2 2 1 CD47 immunoglobulin-like domain Syndecan PF01034.20 KFP05830.1 - 0.01 15.7 0.2 0.037 13.9 0.2 1.9 2 0 0 2 2 2 0 Syndecan domain Shisa PF13908.6 KFP05830.1 - 0.014 15.7 0.3 0.024 14.9 0.3 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Izumo-Ig PF16706.5 KFP05830.1 - 0.014 15.5 0.0 1 9.5 0.0 2.4 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Mucin15 PF15672.5 KFP05830.1 - 0.068 12.7 2.6 0.061 12.8 0.8 1.7 1 1 1 2 2 2 0 Cell-membrane associated Mucin15 C2-set PF05790.15 KFP05830.1 - 0.068 13.4 0.3 6.5 7.0 0.0 2.7 3 0 0 3 3 2 0 Immunoglobulin C2-set domain Keratin PF02422.16 KFP05831.1 - 1.8e-23 82.0 8.8 2.1e-23 81.9 8.8 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFP05832.1 - 9e-21 73.4 14.6 9.3e-21 73.3 14.6 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.8 KFP05832.1 - 3.3 8.0 10.9 8.5 6.7 10.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.16 KFP05833.1 - 2.3e-29 100.9 11.6 2.9e-29 100.6 11.6 1.2 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.8 KFP05833.1 - 0.0079 16.4 3.6 0.0097 16.1 3.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3432) Keratin PF02422.16 KFP05834.1 - 3.7e-32 109.9 14.5 3.7e-32 109.9 14.5 2.0 1 1 1 2 2 2 1 Keratin DUF3432 PF11914.8 KFP05834.1 - 0.15 12.3 4.0 0.22 11.8 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Cornifin PF02389.15 KFP05834.1 - 0.25 11.5 10.5 0.29 11.3 10.5 1.1 1 0 0 1 1 1 0 Cornifin (SPRR) family Keratin PF02422.16 KFP05835.1 - 3.5e-28 97.1 11.2 3.7e-28 97.0 11.2 1.0 1 0 0 1 1 1 1 Keratin Cornifin PF02389.15 KFP05835.1 - 0.0013 18.9 7.7 0.0015 18.7 7.7 1.1 1 0 0 1 1 1 1 Cornifin (SPRR) family DUF3432 PF11914.8 KFP05835.1 - 0.084 13.1 3.2 0.12 12.7 3.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) DUF3292 PF11696.8 KFP05835.1 - 0.16 10.3 0.1 0.2 10.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Keratin PF02422.16 KFP05836.1 - 3e-28 97.4 17.2 3.1e-28 97.3 17.2 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFP05837.1 - 1.3e-26 92.1 18.1 1.4e-26 92.0 18.1 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFP05838.1 - 6.4e-30 102.7 13.6 7e-30 102.6 13.6 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.8 KFP05838.1 - 0.055 13.7 8.8 0.11 12.7 8.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.16 KFP05839.1 - 5.5e-33 112.5 8.6 6.1e-33 112.4 8.6 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.8 KFP05839.1 - 0.4 11.0 5.9 0.78 10.0 5.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.16 KFP05840.1 - 8.8e-31 105.5 10.5 9.3e-31 105.4 10.5 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.8 KFP05840.1 - 0.11 12.7 3.5 0.21 11.8 3.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.16 KFP05841.1 - 1.6e-43 146.3 6.8 2e-43 146.0 6.8 1.1 1 0 0 1 1 1 1 Keratin Fer4_4 PF12800.7 KFP05841.1 - 0.49 11.0 3.8 19 6.1 0.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Keratin PF02422.16 KFP05843.1 - 1.4e-39 133.7 9.8 2.3e-39 133.0 9.8 1.4 1 1 0 1 1 1 1 Keratin Lamprin PF06403.11 KFP05843.1 - 0.73 9.8 25.1 0.98 9.4 25.1 1.2 1 0 0 1 1 1 0 Lamprin DUF3265 PF11665.8 KFP05843.1 - 7 7.0 9.9 8 6.8 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3265) Keratin PF02422.16 KFP05845.1 - 4.1e-37 125.8 5.8 4.1e-37 125.8 5.8 1.9 1 1 1 2 2 2 1 Keratin Tetraspanin PF00335.20 KFP05847.1 - 1.2e-50 172.4 9.0 1.3e-50 172.2 9.0 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2981 PF11200.8 KFP05847.1 - 0.0024 17.7 2.3 0.0034 17.2 2.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2981) GATase_5 PF13507.6 KFP05847.1 - 0.046 12.8 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Tetraspanin PF00335.20 KFP05848.1 - 1.7e-49 168.6 7.9 1.9e-49 168.4 7.9 1.0 1 0 0 1 1 1 1 Tetraspanin family p53-inducible11 PF14936.6 KFP05849.1 - 9.8e-90 299.5 1.2 1.1e-89 299.3 1.2 1.0 1 0 0 1 1 1 1 Tumour protein p53-inducible protein 11 DUF4345 PF14248.6 KFP05849.1 - 0.00016 21.5 0.7 0.00016 21.5 0.7 1.9 1 1 0 2 2 2 1 Domain of unknown function (DUF4345) DUF3325 PF11804.8 KFP05849.1 - 0.027 14.6 1.3 0.15 12.2 1.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3325) DUF2647 PF10839.8 KFP05849.1 - 0.035 14.2 0.2 0.078 13.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2647) SET PF00856.28 KFP05850.1 - 1.7e-05 25.3 0.4 0.00011 22.7 0.0 2.1 2 0 0 2 2 2 1 SET domain zf_PR_Knuckle PF18445.1 KFP05850.1 - 7.8e-05 22.4 1.7 0.00023 20.9 1.7 1.8 1 0 0 1 1 1 1 PR zinc knuckle motif C2 PF00168.30 KFP05851.1 - 1.5e-24 86.2 0.1 1.9e-14 53.8 0.1 2.3 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 KFP05851.1 - 3.7e-05 23.7 0.1 0.025 14.5 0.0 2.9 2 1 1 3 3 3 2 Phosphoinositide 3-kinase C2 2OG-FeII_Oxy_4 PF13661.6 KFP05851.1 - 0.0095 16.6 0.1 0.025 15.3 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Astacin PF01400.24 KFP05852.1 - 1.3e-59 201.1 0.2 2.7e-59 200.0 0.0 1.6 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) CUB PF00431.20 KFP05852.1 - 2.8e-31 108.1 0.0 8e-31 106.6 0.0 1.8 2 0 0 2 2 2 1 CUB domain C1_2 PF03107.16 KFP05852.1 - 0.081 13.3 0.1 17 5.8 0.0 2.8 2 0 0 2 2 2 0 C1 domain DUF5600 PF18150.1 KFP05853.1 - 3.5e-46 156.2 2.3 7e-46 155.2 2.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 KFP05853.1 - 1.6e-15 57.0 0.0 6.6e-15 54.9 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Dynamin_N PF00350.23 KFP05853.1 - 1.8e-13 50.9 0.0 1.4e-12 48.0 0.0 2.4 2 1 0 2 2 2 1 Dynamin family EHD_N PF16880.5 KFP05853.1 - 2.8e-09 36.7 4.2 2.8e-09 36.7 4.2 2.1 2 0 0 2 2 2 1 N-terminal EH-domain containing protein MMR_HSR1 PF01926.23 KFP05853.1 - 1.6e-07 31.4 0.0 4.6e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 KFP05853.1 - 0.00047 19.5 0.6 0.0018 17.7 0.1 2.3 2 0 0 2 2 2 1 EF hand Roc PF08477.13 KFP05853.1 - 0.0029 17.8 0.0 1.4 9.1 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_7 PF13499.6 KFP05853.1 - 0.01 16.3 0.0 0.072 13.5 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair AAA_16 PF13191.6 KFP05853.1 - 0.04 14.3 0.1 0.23 11.8 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 KFP05853.1 - 0.057 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KFP05853.1 - 0.057 12.9 0.1 0.41 10.2 0.1 2.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain EF-hand_8 PF13833.6 KFP05853.1 - 0.088 12.7 0.7 1.9 8.4 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain pair cobW PF02492.19 KFP05853.1 - 0.13 11.8 0.1 22 4.6 0.0 2.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain RcsD_ABL PF16359.5 KFP05853.1 - 0.14 12.3 0.1 0.32 11.2 0.1 1.5 1 0 0 1 1 1 0 RcsD-ABL domain TsaE PF02367.17 KFP05853.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PLA2_B PF01735.18 KFP05854.1 - 8.2e-27 93.8 0.0 1.1e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain cPLA2_C2 PF18695.1 KFP05854.1 - 6.3e-18 64.8 0.0 1.6e-17 63.5 0.0 1.7 1 1 0 1 1 1 1 Cytosolic phospholipases A2 C2-domain PLA2_B PF01735.18 KFP05855.1 - 1.7e-36 125.7 0.1 7e-33 113.8 0.1 2.5 2 1 0 2 2 2 2 Lysophospholipase catalytic domain cPLA2_C2 PF18695.1 KFP05855.1 - 6.4e-22 77.6 5.0 9.5e-20 70.6 0.5 3.3 3 0 0 3 3 3 2 Cytosolic phospholipases A2 C2-domain C2 PF00168.30 KFP05855.1 - 5.8e-18 65.1 0.5 1.7e-17 63.6 0.1 2.0 2 0 0 2 2 2 1 C2 domain PLA2_B PF01735.18 KFP05856.1 - 1.1e-33 116.5 0.1 3.1e-32 111.6 0.1 2.6 2 1 1 3 3 3 1 Lysophospholipase catalytic domain cPLA2_C2 PF18695.1 KFP05856.1 - 8.4e-27 93.4 0.2 2.1e-26 92.1 0.2 1.6 1 0 0 1 1 1 1 Cytosolic phospholipases A2 C2-domain C2 PF00168.30 KFP05856.1 - 4.5e-13 49.4 0.2 1.3e-12 47.9 0.2 1.8 1 0 0 1 1 1 1 C2 domain PLA2_B PF01735.18 KFP05857.1 - 1.8e-25 89.3 0.0 2.2e-25 89.1 0.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF1133 PF06576.11 KFP05857.1 - 0.0099 15.3 0.1 0.015 14.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1133) C2 PF00168.30 KFP05858.1 - 6.5e-16 58.5 1.1 1e-15 57.9 0.5 1.6 1 1 1 2 2 2 1 C2 domain PLA2_B PF01735.18 KFP05859.1 - 1.1e-40 139.6 0.1 6e-34 117.3 0.0 2.9 2 1 1 3 3 3 3 Lysophospholipase catalytic domain cPLA2_C2 PF18695.1 KFP05859.1 - 1.3e-24 86.3 0.1 2.6e-24 85.3 0.1 1.5 1 0 0 1 1 1 1 Cytosolic phospholipases A2 C2-domain Vps39_1 PF10366.9 KFP05860.1 - 1.1e-32 112.5 3.1 1.1e-32 112.5 3.1 3.2 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KFP05860.1 - 2.2e-31 108.5 4.8 2.2e-31 108.5 4.8 2.7 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 KFP05860.1 - 5.7e-31 108.1 0.1 1.3e-30 106.9 0.1 1.6 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.20 KFP05860.1 - 2.9e-11 43.4 10.1 1.2e-06 28.5 1.0 4.1 3 1 0 3 3 3 2 Region in Clathrin and VPS WD40_like PF17005.5 KFP05860.1 - 0.0018 17.6 0.4 0.0083 15.5 0.0 2.1 2 0 0 2 2 2 1 WD40-like domain Lung_7-TM_R PF06814.13 KFP05861.1 - 5.4e-79 265.5 24.2 2.7e-77 259.9 24.2 2.1 1 1 0 1 1 1 1 Lung seven transmembrane receptor SNAD4 PF18750.1 KFP05861.1 - 0.00032 20.8 0.1 0.00085 19.4 0.1 1.6 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 KFP05861.1 - 0.0065 16.5 0.2 0.024 14.7 0.2 1.9 2 0 0 2 2 2 1 APOBEC2 NAD2 PF18782.1 KFP05861.1 - 0.02 15.0 0.2 0.067 13.3 0.2 1.9 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 NAD1 PF18778.1 KFP05861.1 - 0.043 13.9 0.6 0.09 12.9 0.1 1.7 2 0 0 2 2 2 0 Novel AID APOBEC clade 1 SPT6_acidic PF14632.6 KFP05861.1 - 0.061 13.9 1.1 0.12 13.0 1.1 1.3 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Glyco_hydro_31 PF01055.26 KFP05862.1 - 3.1e-140 468.2 1.4 4.2e-140 467.8 0.9 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KFP05862.1 - 2.3e-17 63.1 0.1 1.1e-16 60.9 0.1 2.3 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 KFP05862.1 - 8.8e-05 22.7 0.0 0.0003 21.0 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) NtCtMGAM_N PF16863.5 KFP05862.1 - 0.0035 17.5 0.1 0.008 16.4 0.1 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Peptidase_C2 PF00648.21 KFP05863.1 - 4e-139 462.7 0.4 6.1e-139 462.1 0.4 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KFP05863.1 - 9.5e-53 178.2 0.0 2.2e-52 177.1 0.0 1.7 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_1 PF00036.32 KFP05863.1 - 1.6e-18 64.8 12.3 2.8e-07 29.6 0.1 6.0 6 0 0 6 6 6 3 EF hand Calpain_u2 PF16648.5 KFP05863.1 - 7e-18 64.9 3.1 1.6e-17 63.7 3.1 1.6 1 0 0 1 1 1 1 Unstructured region on Calpain-3 EF-hand_6 PF13405.6 KFP05863.1 - 1.6e-15 55.6 8.7 0.00025 20.7 0.0 5.5 6 0 0 6 6 6 4 EF-hand domain EF-hand_8 PF13833.6 KFP05863.1 - 7.6e-13 48.1 13.8 6.8e-10 38.6 0.6 4.8 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP05863.1 - 1.8e-11 43.0 6.4 0.0014 18.0 0.0 4.6 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 KFP05863.1 - 2.4e-11 43.9 9.1 0.00016 22.0 0.4 4.6 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 KFP05863.1 - 0.028 14.4 3.5 0.66 10.0 0.3 2.7 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand CEP76-C2 PF15627.6 KFP05863.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 CEP76 C2 domain Ndufs5 PF10200.9 KFP05863.1 - 1.7 9.0 3.7 2.4 8.4 0.0 2.8 3 0 0 3 3 3 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa WD40 PF00400.32 KFP05864.1 - 3.5e-18 65.6 4.8 0.018 15.9 0.1 7.1 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP05864.1 - 5.9e-06 26.5 2.6 0.94 9.8 0.0 5.1 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KFP05864.1 - 0.0023 18.4 2.3 61 4.3 0.0 5.3 6 0 0 6 6 6 0 PQQ-like domain zf-C2H2_aberr PF17017.5 KFP05864.1 - 0.0059 16.8 0.3 0.013 15.7 0.3 1.5 1 0 0 1 1 1 1 Aberrant zinc-finger WD40_like PF17005.5 KFP05864.1 - 0.015 14.6 2.4 0.18 11.1 0.2 2.1 2 0 0 2 2 2 0 WD40-like domain FOXP-CC PF16159.5 KFP05864.1 - 0.14 12.8 5.9 1.2 9.9 4.2 2.8 1 1 1 2 2 2 0 FOXP coiled-coil domain SNAP-25 PF00835.19 KFP05865.1 - 8.4e-23 80.4 1.0 1.6e-22 79.6 1.0 1.5 1 0 0 1 1 1 1 SNAP-25 family DUF5089 PF17002.5 KFP05865.1 - 1.5e-06 28.3 1.9 2.8e-06 27.3 1.9 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF5089) V-SNARE_C PF12352.8 KFP05865.1 - 9.8e-06 25.8 5.5 0.0043 17.3 1.2 2.7 2 1 1 3 3 3 2 Snare region anchored in the vesicle membrane C-terminus SOAR PF16533.5 KFP05865.1 - 0.029 14.3 0.5 0.29 11.1 0.1 2.3 2 0 0 2 2 2 0 STIM1 Orai1-activating region DUF16 PF01519.16 KFP05865.1 - 0.042 14.3 4.4 5.9 7.4 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 KFP05865.1 - 0.079 13.4 3.4 5.7 7.5 0.4 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Sec20 PF03908.13 KFP05865.1 - 0.11 12.4 2.1 0.11 12.5 0.7 1.6 2 0 0 2 2 2 0 Sec20 DUF1664 PF07889.12 KFP05865.1 - 0.12 12.4 6.1 0.29 11.2 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Sulfatase_C PF14707.6 KFP05865.1 - 0.13 13.0 0.6 1.1 10.1 0.2 2.1 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase DUF948 PF06103.11 KFP05865.1 - 0.42 10.9 2.4 5 7.5 0.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) UPF0242 PF06785.11 KFP05865.1 - 1.1 9.3 5.0 11 6.1 5.0 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LRR_8 PF13855.6 KFP05866.1 - 5.8e-22 77.2 38.1 1.9e-08 34.0 0.3 4.1 1 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KFP05866.1 - 7.1e-20 70.8 28.8 4e-06 27.1 0.6 4.7 3 1 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP05866.1 - 9.3e-09 35.0 8.6 1.3e-05 24.7 1.2 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFP05866.1 - 1.2e-07 31.3 24.6 0.33 11.7 0.3 7.6 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.6 KFP05866.1 - 1.5e-05 24.6 23.8 2.1 8.6 0.1 7.5 7 0 0 7 7 7 4 Leucine Rich repeat RsmF_methylt_CI PF17126.5 KFP05866.1 - 0.0015 18.5 0.3 2.1 8.5 0.1 4.3 2 1 1 4 4 4 1 RsmF rRNA methyltransferase first C-terminal domain HAUS2 PF15003.6 KFP05867.1 - 5.1e-35 120.9 4.2 5.6e-35 120.8 4.2 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 Laminin_II PF06009.12 KFP05867.1 - 0.017 15.2 0.7 0.038 14.0 0.3 1.7 1 1 0 1 1 1 0 Laminin Domain II DUF3910 PF13049.6 KFP05867.1 - 0.041 14.2 0.0 0.066 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3910) Vac_Fusion PF02346.16 KFP05867.1 - 1.9 8.1 5.9 2.2 8.0 0.1 2.8 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 Kinesin PF00225.23 KFP05868.1 - 1.8e-69 234.3 0.0 2.2e-39 135.3 0.0 3.4 4 0 0 4 4 4 2 Kinesin motor domain Microtub_bd PF16796.5 KFP05868.1 - 1.3e-21 77.0 0.1 3.5e-20 72.5 0.0 2.7 2 0 0 2 2 2 1 Microtubule binding FHA PF00498.26 KFP05868.1 - 8.1e-06 26.1 0.2 3.1e-05 24.2 0.2 2.1 1 0 0 1 1 1 1 FHA domain Kinesin_assoc PF16183.5 KFP05868.1 - 3.4e-05 24.1 0.5 3.4e-05 24.1 0.5 4.8 4 1 1 5 5 5 2 Kinesin-associated Yop-YscD_cpl PF16697.5 KFP05868.1 - 0.0014 18.9 0.0 0.007 16.7 0.0 2.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain START PF01852.19 KFP05869.1 - 2.2e-11 43.6 0.0 3.7e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 START domain Peptidase_C98 PF15499.6 KFP05869.1 - 0.52 9.7 3.2 0.98 8.8 3.2 1.4 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF1168 PF06658.12 KFP05869.1 - 2.1 8.2 11.4 1.6 8.5 7.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) DUF87 PF01935.17 KFP05869.1 - 7.9 6.5 6.0 13 5.8 6.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain Pkinase PF00069.25 KFP05870.1 - 4.8e-30 104.8 0.0 8.4e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP05870.1 - 1e-17 64.3 0.0 1.6e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SPATA19 PF15212.6 KFP05870.1 - 0.076 13.2 0.1 0.21 11.8 0.1 1.7 1 0 0 1 1 1 0 Spermatogenesis-associated protein 19, mitochondrial Tetraspanin PF00335.20 KFP05871.1 - 1e-19 71.2 7.8 1.2e-19 70.9 7.8 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF1218 PF06749.12 KFP05871.1 - 0.0064 17.0 1.3 0.78 10.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1218) ArfGap PF01412.18 KFP05871.1 - 0.088 12.9 4.1 0.17 11.9 4.1 1.7 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf RVT_1 PF00078.27 KFP05872.1 - 1.9e-16 60.2 0.0 2.9e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) dUTPase PF00692.19 KFP05873.1 - 3.3e-17 62.4 0.0 4.3e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 dUTPase TIR PF01582.20 KFP05874.1 - 1.9e-28 99.5 0.0 2.9e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 KFP05874.1 - 9.6e-07 29.4 0.0 1.8e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 TIR domain ig PF00047.25 KFP05874.1 - 1.8e-06 28.0 0.0 3.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFP05874.1 - 4.3e-06 27.2 0.0 8.8e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP05874.1 - 9.9e-06 25.5 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP05874.1 - 0.00079 19.7 0.0 0.0023 18.2 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin domain Hormone_recep PF00104.30 KFP05875.1 - 5e-20 72.0 0.0 2.2e-19 69.8 0.0 1.8 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor NR_Repeat PF14046.6 KFP05875.1 - 0.0013 18.8 1.7 0.0038 17.3 1.7 1.9 1 0 0 1 1 1 1 Nuclear receptor repeat DUF4569 PF15133.6 KFP05876.1 - 8.4e-100 334.4 5.1 9.5e-100 334.2 5.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4569) FGGY_N PF00370.21 KFP05877.1 - 2e-76 256.8 0.1 2.9e-76 256.3 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KFP05877.1 - 8.9e-63 211.6 0.4 3.1e-62 209.8 0.2 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain CUE PF02845.16 KFP05878.1 - 1.1e-09 37.8 0.2 3e-09 36.4 0.2 1.8 2 0 0 2 2 2 1 CUE domain zf-RanBP PF00641.18 KFP05878.1 - 5.7e-05 22.4 1.7 5.7e-05 22.4 1.7 1.8 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others DUF2201 PF09967.9 KFP05878.1 - 0.1 12.8 0.1 0.27 11.4 0.0 1.7 2 0 0 2 2 2 0 VWA-like domain (DUF2201) HALZ PF02183.18 KFP05879.1 - 0.0021 18.3 8.7 0.085 13.1 3.8 2.4 2 0 0 2 2 2 2 Homeobox associated leucine zipper APG6_N PF17675.1 KFP05879.1 - 0.0049 17.4 0.7 0.0077 16.8 0.7 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region LRRFIP PF09738.9 KFP05879.1 - 0.016 14.7 1.0 0.016 14.7 1.0 1.3 1 0 0 1 1 1 0 LRRFIP family SOGA PF11365.8 KFP05879.1 - 0.035 15.2 2.1 0.078 14.1 2.1 1.8 1 1 0 1 1 1 0 Protein SOGA bZIP_1 PF00170.21 KFP05879.1 - 0.1 12.7 0.9 0.1 12.7 0.9 2.0 2 0 0 2 2 2 0 bZIP transcription factor Nnf1 PF03980.14 KFP05879.1 - 0.18 12.2 4.7 0.2 12.1 3.4 1.9 2 1 0 2 2 2 0 Nnf1 YabA PF06156.13 KFP05879.1 - 0.22 12.2 3.9 0.11 13.2 1.3 1.8 2 0 0 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 KFP05879.1 - 0.35 11.3 9.8 1.7 9.1 4.8 2.5 3 0 0 3 3 3 0 Cell division protein ZapB GIT_CC PF16559.5 KFP05879.1 - 2.2 8.2 6.3 0.58 10.1 1.9 2.1 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1043 PF06295.12 KFP05879.1 - 2.5 8.1 6.1 0.33 10.9 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Spectrin PF00435.21 KFP05880.1 - 2.6e-178 580.7 280.3 5e-20 72.0 4.0 24.7 24 1 0 24 24 24 22 Spectrin repeat CH PF00307.31 KFP05880.1 - 1.8e-43 147.2 9.3 1.5e-20 73.4 0.0 5.6 4 0 0 4 4 4 3 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFP05880.1 - 3.3e-07 30.0 0.2 0.0011 18.7 0.0 4.1 4 0 0 4 4 4 2 CAMSAP CH domain Anti-adapt_IraP PF10796.9 KFP05880.1 - 1.2 9.8 7.6 0.7 10.5 0.1 5.0 3 0 0 3 3 3 0 Sigma-S stabilisation anti-adaptor protein Git3 PF11710.8 KFP05882.1 - 0.016 15.0 1.1 0.018 14.8 1.1 1.1 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 L_HMGIC_fpl PF10242.9 KFP05882.1 - 0.017 15.3 3.8 0.026 14.8 3.8 1.2 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 KFP05882.1 - 0.018 14.8 10.4 0.024 14.4 10.4 1.3 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 KFP05882.1 - 0.077 12.9 3.6 0.1 12.5 3.6 1.2 1 0 0 1 1 1 0 Tight junction protein, Claudin-like ApoO PF09769.9 KFP05882.1 - 0.19 11.7 1.5 0.26 11.3 1.5 1.3 1 0 0 1 1 1 0 Apolipoprotein O DUF3525 PF12039.8 KFP05882.1 - 0.2 10.3 0.3 0.24 10.1 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) SUR7 PF06687.12 KFP05882.1 - 0.45 10.1 7.8 0.6 9.7 7.8 1.2 1 0 0 1 1 1 0 SUR7/PalI family DUF2721 PF11026.8 KFP05882.1 - 0.73 9.7 6.4 1.1 9.2 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) 2TM PF13239.6 KFP05882.1 - 0.81 10.0 3.9 0.28 11.5 1.4 1.6 1 1 1 2 2 2 0 2TM domain Yip1 PF04893.17 KFP05882.1 - 1.1 8.9 12.6 1.7 8.3 12.6 1.3 1 1 0 1 1 1 0 Yip1 domain Glu_cys_ligase PF04262.14 KFP05884.1 - 0.1 11.2 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase ASH PF15780.5 KFP05885.1 - 0.0015 18.7 0.0 0.0026 17.9 0.0 1.4 1 1 1 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 KFP05885.1 - 0.08 13.2 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 131-like UFD1 PF03152.14 KFP05885.1 - 0.16 11.4 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 CAMSAP_CH PF11971.8 KFP05886.1 - 2.7e-05 23.9 0.1 0.00015 21.5 0.0 2.2 2 0 0 2 2 2 1 CAMSAP CH domain CH PF00307.31 KFP05886.1 - 0.015 15.4 0.8 0.062 13.5 0.2 2.3 2 1 0 2 2 2 0 Calponin homology (CH) domain LANC_like PF05147.13 KFP05888.1 - 3.4e-61 206.8 0.0 4.2e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein C5-epim_C PF06662.13 KFP05888.1 - 0.051 13.1 0.9 3.6 7.1 0.2 2.3 1 1 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_127 PF07944.12 KFP05888.1 - 0.11 10.9 0.0 0.39 9.1 0.0 1.6 1 1 1 2 2 2 0 Beta-L-arabinofuranosidase, GH127 XK-related PF09815.9 KFP05889.1 - 7.6e-67 225.8 20.6 8.9e-67 225.6 20.6 1.1 1 0 0 1 1 1 1 XK-related protein Ferric_reduct PF01794.19 KFP05890.1 - 1.7e-24 86.3 6.9 1.7e-24 86.3 6.9 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KFP05890.1 - 4e-22 79.0 0.1 7.5e-13 48.9 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFP05890.1 - 6.7e-22 77.7 0.2 1.6e-21 76.4 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain FAD_binding_6 PF00970.24 KFP05890.1 - 0.00013 22.2 0.0 0.00027 21.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Tctex-1 PF03645.13 KFP05891.1 - 2.2e-30 104.9 2.7 2.4e-30 104.8 2.7 1.0 1 0 0 1 1 1 1 Tctex-1 family C2 PF00168.30 KFP05892.1 - 5.3e-45 151.9 0.6 9.5e-23 80.4 0.1 2.3 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.16 KFP05892.1 - 1.4e-18 67.2 9.4 2.5e-18 66.4 9.4 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger PI3K_C2 PF00792.24 KFP05892.1 - 0.0057 16.6 0.5 0.14 12.0 0.1 2.3 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 DUF4174 PF13778.6 KFP05893.1 - 5.5e-31 107.5 0.0 7.5e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) HYR PF02494.16 KFP05893.1 - 1.5e-28 99.0 0.0 2.7e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 HYR domain Sushi PF00084.20 KFP05893.1 - 7.4e-25 87.3 26.8 5e-11 43.0 3.9 3.4 3 0 0 3 3 3 3 Sushi repeat (SCR repeat) RCC1 PF00415.18 KFP05894.1 - 2.6e-71 236.1 15.1 1.2e-12 48.3 0.1 7.9 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFP05894.1 - 3.3e-40 135.1 19.7 1.7e-08 34.0 0.1 7.8 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Kelch_2 PF07646.15 KFP05894.1 - 0.0008 19.3 0.0 7.5 6.7 0.0 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 KFP05894.1 - 0.0091 16.0 7.9 1.5 8.9 0.1 4.6 4 0 0 4 4 4 2 Galactose oxidase, central domain OTCace PF00185.24 KFP05895.1 - 2.3e-52 177.2 0.0 3.3e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 KFP05895.1 - 5.4e-44 149.8 0.0 9.1e-44 149.1 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain BCOR PF15808.5 KFP05896.1 - 1.1e-78 264.5 28.2 1.1e-78 264.5 28.2 2.9 3 0 0 3 3 3 1 BCL-6 co-repressor, non-ankyrin-repeat region PUFD PF16553.5 KFP05896.1 - 5.4e-53 178.0 0.5 1.5e-52 176.6 0.5 1.8 1 0 0 1 1 1 1 BCORL-PCGF1-binding domain Ank_2 PF12796.7 KFP05896.1 - 1.2e-14 54.7 0.5 7.3e-14 52.1 0.3 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP05896.1 - 3.4e-14 51.5 0.9 8.5e-05 22.7 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KFP05896.1 - 3.6e-12 46.2 2.0 2.5e-08 34.0 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP05896.1 - 1.4e-11 44.7 6.0 3.8e-06 27.3 0.3 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFP05896.1 - 1.1e-08 35.1 0.8 0.02 15.3 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeat Renin_r PF07850.14 KFP05897.1 - 4.5e-37 126.6 1.2 7.2e-37 125.9 1.2 1.3 1 0 0 1 1 1 1 Renin receptor-like protein Glycophorin_A PF01102.18 KFP05897.1 - 0.048 13.9 0.0 0.091 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A DUF2273 PF10031.9 KFP05897.1 - 0.089 12.8 1.0 0.16 12.0 1.0 1.4 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) Med14 PF08638.11 KFP05898.1 - 9.8e-52 175.2 0.0 2.4e-51 173.9 0.0 1.7 1 0 0 1 1 1 1 Mediator complex subunit MED14 RE_SinI PF09570.10 KFP05898.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 SinI restriction endonuclease UCH PF00443.29 KFP05899.1 - 3.9e-50 170.7 0.6 2.3e-49 168.2 0.1 2.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP05899.1 - 3e-27 96.0 0.0 9.2e-26 91.2 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1722 PF08349.11 KFP05899.1 - 0.055 13.8 0.0 15 5.9 0.0 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Vps23_core PF09454.10 KFP05899.1 - 0.07 13.1 0.5 0.48 10.4 0.1 2.8 3 0 0 3 3 3 0 Vps23 core domain FAST_1 PF06743.15 KFP05899.1 - 0.11 12.5 0.2 1.3 9.0 0.0 2.9 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 Cas9_a PF18470.1 KFP05899.1 - 0.18 11.3 0.7 0.46 10.0 0.6 1.7 1 1 0 1 1 1 0 Cas9 alpha-helical lobe domain RVT_1 PF00078.27 KFP05900.1 - 0.066 12.7 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L2_C PF03947.18 KFP05901.1 - 1.2e-48 164.5 3.0 1.9e-48 163.8 3.0 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KFP05901.1 - 3.6e-19 68.5 0.1 1.2e-18 66.8 0.1 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Guanylate_kin PF00625.21 KFP05902.1 - 1.5e-62 210.5 0.1 2e-62 210.1 0.1 1.2 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.17 KFP05902.1 - 6.4e-13 48.2 0.0 1.2e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP05902.1 - 1.7e-08 33.9 0.9 4.5e-08 32.6 0.9 1.8 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP05902.1 - 1.9e-05 24.4 0.0 4.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain 7tm_1 PF00001.21 KFP05903.1 - 8e-18 64.7 26.1 3.5e-16 59.3 26.1 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Amino_oxidase PF01593.24 KFP05904.1 - 2.7e-69 234.6 0.0 3.3e-69 234.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFP05904.1 - 1.1e-09 38.4 0.0 3.5e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KFP05904.1 - 0.019 14.2 0.4 0.068 12.4 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFP05904.1 - 0.093 12.0 0.1 0.2 10.9 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 KFP05905.1 - 9.1e-74 249.4 0.0 1.1e-73 249.1 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFP05905.1 - 7.8e-08 32.4 0.0 2.4e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Cys_knot PF00007.22 KFP05906.1 - 2.4e-06 27.8 13.0 3.5e-06 27.3 13.0 1.2 1 0 0 1 1 1 1 Cystine-knot domain DAN PF03045.15 KFP05906.1 - 9.5e-06 25.6 10.0 1.2e-05 25.4 10.0 1.1 1 0 0 1 1 1 1 DAN domain DUF1126 PF06565.12 KFP05907.1 - 6.7e-102 334.4 3.7 1.3e-32 111.7 0.0 4.3 3 1 0 3 3 3 3 DUF1126 PH-like domain DUF5580 PF17743.1 KFP05907.1 - 0.0085 14.7 0.1 0.012 14.1 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) EF-hand_1 PF00036.32 KFP05907.1 - 0.016 14.8 0.0 0.061 12.9 0.0 2.1 1 0 0 1 1 1 0 EF hand FUN14 PF04930.15 KFP05908.1 - 1.5e-29 102.2 2.7 1.9e-29 101.9 2.7 1.1 1 0 0 1 1 1 1 FUN14 family EutA PF06277.11 KFP05908.1 - 0.053 12.4 0.1 0.063 12.1 0.1 1.0 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA SPC12 PF06645.13 KFP05908.1 - 0.56 10.3 2.9 0.96 9.6 0.9 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) JmjC PF02373.22 KFP05909.1 - 1.3e-31 109.4 1.9 1.3e-31 109.4 1.9 2.2 2 0 0 2 2 2 1 JmjC domain, hydroxylase TPR_1 PF00515.28 KFP05909.1 - 1e-29 101.1 19.1 2e-06 27.4 0.2 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 KFP05909.1 - 2.3e-19 67.9 17.8 0.0012 18.8 0.4 8.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFP05909.1 - 3.4e-15 54.9 16.6 0.0017 18.4 0.7 7.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFP05909.1 - 3.6e-15 56.3 1.2 0.0011 19.5 1.2 5.2 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFP05909.1 - 6.3e-12 45.6 9.8 0.021 15.1 0.4 5.3 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.6 KFP05909.1 - 6.9e-12 44.9 5.4 0.0046 17.2 0.0 5.4 7 0 0 7 7 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFP05909.1 - 4.8e-07 29.8 1.8 0.0076 16.4 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP05909.1 - 1e-06 29.1 4.0 1.5 9.9 0.0 5.9 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP05909.1 - 1.1e-06 29.0 10.7 0.032 14.7 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFP05909.1 - 5.2e-06 26.1 7.5 1.1 9.5 0.0 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFP05909.1 - 0.00014 21.4 16.4 0.089 12.5 0.0 7.2 4 3 4 8 8 8 2 TPR repeat TPR_15 PF13429.6 KFP05909.1 - 0.06 12.6 5.7 0.45 9.7 1.9 3.5 1 1 1 2 2 2 0 Tetratricopeptide repeat SNAP PF14938.6 KFP05909.1 - 0.077 12.4 13.6 0.05 13.0 2.0 3.1 2 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP ANAPC3 PF12895.7 KFP05909.1 - 0.6 10.4 0.0 0.6 10.4 0.0 4.0 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KFP05909.1 - 0.8 10.5 11.0 44 5.0 0.1 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat PIP49_C PF12260.8 KFP05910.1 - 3.6e-42 144.1 0.0 6.6e-42 143.3 0.0 1.4 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 DUF1340 PF07067.11 KFP05910.1 - 0.34 10.3 1.5 0.73 9.2 0.7 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1340) V-set PF07686.17 KFP05911.1 - 3.4e-13 49.7 4.2 1.3e-10 41.4 0.2 2.4 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP05911.1 - 1.4e-12 48.0 1.5 5.9e-06 26.8 0.4 2.6 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP05911.1 - 1e-11 44.8 4.3 1.3e-05 25.2 0.1 3.6 2 2 1 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 KFP05911.1 - 7.3e-10 38.8 0.4 4e-09 36.4 0.1 2.3 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain I-set PF07679.16 KFP05911.1 - 1.4e-09 37.8 0.1 0.00039 20.4 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP05911.1 - 1.1e-06 28.9 2.6 0.00066 20.0 0.4 2.9 2 1 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.15 KFP05911.1 - 5.3e-05 23.5 3.8 0.0011 19.3 0.1 3.2 2 1 1 3 3 3 1 Immunoglobulin C1-set domain Lep_receptor_Ig PF06328.11 KFP05911.1 - 0.00018 21.4 4.3 0.037 14.0 0.0 3.2 3 1 1 4 4 4 2 Ig-like C2-type domain MLANA PF14991.6 KFP05911.1 - 0.0074 16.6 3.4 0.0076 16.5 1.3 2.1 2 1 1 3 3 3 1 Protein melan-A DUF2207 PF09972.9 KFP05911.1 - 0.025 13.4 0.0 0.034 12.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2987 PF11205.8 KFP05911.1 - 0.039 13.9 1.0 0.043 13.7 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2987) YabA PF06156.13 KFP05911.1 - 0.18 12.5 2.2 0.2 12.3 0.7 1.8 2 0 0 2 2 2 0 Initiation control protein YabA V-set PF07686.17 KFP05912.1 - 1.9e-08 34.4 0.1 2.6e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP05912.1 - 0.0002 21.9 0.1 0.001 19.7 0.0 2.1 2 1 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 KFP05912.1 - 0.0012 19.0 0.3 0.023 14.9 0.3 2.3 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP05912.1 - 0.013 15.8 0.1 0.088 13.2 0.1 2.1 1 1 0 1 1 1 0 Immunoglobulin domain V-set_CD47 PF08204.11 KFP05912.1 - 0.034 14.1 0.1 0.048 13.6 0.1 1.2 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain I-set PF07679.16 KFP05912.1 - 0.078 13.1 0.0 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin I-set domain DJ-1_PfpI PF01965.24 KFP05913.1 - 1.3e-06 28.3 0.3 4.3e-06 26.6 0.3 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family WD40 PF00400.32 KFP05914.1 - 3.3e-31 106.8 24.0 1.4e-07 32.0 0.1 11.7 13 0 0 13 13 13 4 WD domain, G-beta repeat Utp12 PF04003.12 KFP05914.1 - 4.5e-24 84.8 0.4 7e-24 84.2 0.4 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KFP05914.1 - 1.2e-18 67.2 0.0 0.088 13.1 0.0 9.0 5 3 5 10 10 10 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP05914.1 - 8.5e-08 32.3 0.5 0.029 14.3 0.0 4.9 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFP05914.1 - 1e-06 27.9 0.1 0.52 9.2 0.1 4.4 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFP05914.1 - 2e-05 24.1 0.5 0.0002 20.8 0.1 2.7 2 1 0 2 2 2 1 WD40-like domain PD40 PF07676.12 KFP05914.1 - 0.00014 21.6 0.1 0.44 10.5 0.0 4.9 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Utp13 PF08625.11 KFP05914.1 - 0.031 14.2 0.4 0.11 12.4 0.4 1.9 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain Osmo_MPGsynth PF09488.10 KFP05914.1 - 0.051 12.3 0.0 0.077 11.7 0.0 1.2 1 0 0 1 1 1 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) Nup160 PF11715.8 KFP05914.1 - 0.11 11.2 3.8 0.11 11.2 0.1 2.4 2 1 0 2 2 2 0 Nucleoporin Nup120/160 TRAPPC10 PF12584.8 KFP05915.1 - 4.6e-28 97.9 0.0 5.5e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.7 KFP05915.1 - 0.18 11.8 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking TRAPPC10 PF12584.8 KFP05916.1 - 1.3e-05 24.9 0.1 2.6e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 Acyltransf_C PF16076.5 KFP05918.1 - 5.3e-28 96.9 0.2 1e-27 96.0 0.2 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 KFP05918.1 - 3.5e-15 55.8 0.0 5.5e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase AKAP95 PF04988.12 KFP05919.1 - 3.1e-20 73.0 2.0 3.4e-20 72.9 2.0 1.0 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.7 KFP05919.1 - 0.0015 18.8 0.0 0.0015 18.8 0.0 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 KFP05919.1 - 0.023 15.0 0.2 0.027 14.7 0.2 1.1 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Actin_micro PF17003.5 KFP05919.1 - 0.024 13.9 0.2 0.024 13.9 0.2 1.0 1 0 0 1 1 1 0 Putative actin-like family DUF3449 PF11931.8 KFP05919.1 - 0.064 13.0 0.5 0.067 13.0 0.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) AKAP95 PF04988.12 KFP05921.1 - 3.1e-74 248.6 7.9 3.1e-74 248.6 7.9 1.6 2 0 0 2 2 2 1 A-kinase anchoring protein 95 (AKAP95) zf-met PF12874.7 KFP05921.1 - 5.2 7.6 7.4 0.75 10.3 0.7 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFP05922.1 - 8.2e-16 57.4 18.3 0.0095 16.7 0.3 5.8 5 0 0 5 5 5 4 C2H2-type zinc finger zf-FCS PF06467.14 KFP05922.1 - 9e-09 35.1 3.1 0.2 11.6 0.0 4.7 5 0 0 5 5 5 3 MYM-type Zinc finger with FCS sequence motif zf-C2H2 PF00096.26 KFP05922.1 - 8.5e-08 32.3 23.8 0.13 12.8 0.3 5.9 5 1 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KFP05922.1 - 0.00038 20.7 4.7 27 5.2 0.0 5.0 5 0 0 5 5 5 0 C2H2 type zinc-finger (2 copies) AnfO_nitrog PF09582.10 KFP05922.1 - 0.0017 17.7 0.0 1.8 7.8 0.0 3.4 4 0 0 4 4 4 1 Iron only nitrogenase protein AnfO (AnfO_nitrog) zf-MYST PF17772.1 KFP05922.1 - 0.0018 17.8 8.3 2.5 7.8 0.1 3.9 4 0 0 4 4 4 2 MYST family zinc finger domain zf-C2H2_3rep PF18868.1 KFP05922.1 - 0.0083 16.8 4.1 83 3.9 0.2 5.0 5 0 0 5 5 5 0 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 KFP05922.1 - 0.015 15.4 15.1 7.6 6.7 0.1 5.4 5 0 0 5 5 5 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 KFP05922.1 - 0.019 15.3 8.9 8.1 6.9 0.1 4.9 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP05922.1 - 0.062 13.7 15.1 2.4 8.7 0.7 5.1 5 0 0 5 5 5 0 Zinc-finger of C2H2 type PyrI_C PF02748.15 KFP05922.1 - 0.11 12.5 5.9 36 4.4 0.1 4.3 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF2256 PF10013.9 KFP05922.1 - 0.18 12.0 2.9 46 4.2 0.0 4.0 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_4 PF13894.6 KFP05923.1 - 7e-10 38.9 23.2 0.13 13.1 0.2 5.6 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP05923.1 - 4.2e-05 23.8 23.3 0.002 18.5 0.2 5.0 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 KFP05923.1 - 0.0015 18.2 9.7 0.31 10.7 0.1 4.1 4 0 0 4 4 4 3 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 KFP05923.1 - 0.0019 18.5 13.6 1.4 9.3 0.0 4.7 3 1 0 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KFP05923.1 - 0.59 10.5 11.0 0.61 10.4 2.4 4.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-Mss51 PF13824.6 KFP05923.1 - 0.66 10.1 9.0 2.1 8.5 0.7 3.7 1 1 2 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 HNH_5 PF14279.6 KFP05923.1 - 1.7 8.6 6.0 7.7 6.5 3.6 2.6 2 0 0 2 2 2 0 HNH endonuclease zf-Di19 PF05605.12 KFP05923.1 - 9.8 6.6 10.2 5.5 7.4 0.1 4.0 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding TED_complement PF07678.14 KFP05924.1 - 3.7e-45 154.3 0.0 4e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 A-macroglobulin TED domain SQHop_cyclase_C PF13243.6 KFP05924.1 - 0.015 14.4 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain WD40 PF00400.32 KFP05925.1 - 1.9e-39 132.9 20.6 0.0014 19.4 0.3 12.8 12 0 0 12 12 12 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP05925.1 - 3.2e-15 56.2 0.3 0.0026 18.0 0.0 7.1 7 1 1 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP05925.1 - 1.5e-05 25.0 0.0 0.00048 20.0 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KFP05925.1 - 0.19 11.0 4.6 2.2 7.5 0.1 3.8 4 0 0 4 4 4 0 WD40-like domain Cytochrom_D1 PF02239.16 KFP05925.1 - 0.66 8.4 2.5 2.6 6.5 0.2 2.8 3 1 0 3 3 3 0 Cytochrome D1 heme domain Pkinase_Tyr PF07714.17 KFP05928.1 - 1.6e-87 293.1 0.0 2.2e-87 292.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP05928.1 - 6e-38 130.7 0.0 8.8e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ig_3 PF13927.6 KFP05928.1 - 1.4e-18 67.3 0.3 2.1e-10 41.0 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFP05928.1 - 2.9e-17 62.5 1.2 4.2e-14 52.4 0.1 2.8 2 1 0 2 2 2 2 Immunoglobulin I-set domain fn3 PF00041.21 KFP05928.1 - 3.5e-15 56.1 0.3 5.2e-09 36.3 0.1 2.6 2 0 0 2 2 2 2 Fibronectin type III domain Ig_2 PF13895.6 KFP05928.1 - 2.6e-14 53.3 0.0 6e-10 39.3 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP05928.1 - 7.4e-12 45.3 0.3 7.9e-09 35.6 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFP05928.1 - 9.5e-06 25.8 0.0 0.002 18.2 0.0 2.8 1 1 0 1 1 1 1 Immunoglobulin V-set domain Kinase-like PF14531.6 KFP05928.1 - 0.21 10.9 0.0 0.37 10.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF4381 PF14316.6 KFP05928.1 - 1.6 8.9 3.9 0.6 10.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) TMEM151 PF14857.6 KFP05929.1 - 3.5e-198 658.8 15.7 4e-198 658.6 15.7 1.0 1 0 0 1 1 1 1 TMEM151 family RPAP1_C PF08620.10 KFP05930.1 - 6.9e-27 93.3 1.0 1.8e-26 92.0 1.0 1.8 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KFP05930.1 - 5e-16 58.2 4.6 1.2e-15 57.0 4.6 1.7 1 0 0 1 1 1 1 RPAP1-like, N-terminal Pkinase_Tyr PF07714.17 KFP05931.1 - 8.2e-87 290.7 0.0 1.2e-86 290.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP05931.1 - 4.9e-32 111.3 0.0 7.2e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Gly_rich PF12810.7 KFP05931.1 - 2.6e-19 70.1 28.9 4.1e-19 69.4 28.9 1.2 1 0 0 1 1 1 1 Glycine rich protein FXa_inhibition PF14670.6 KFP05931.1 - 0.28 11.5 7.5 1.1 9.5 7.5 2.1 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site IPK PF03770.16 KFP05932.1 - 5.5e-42 143.9 0.0 1.3e-41 142.7 0.0 1.6 1 1 0 1 1 1 1 Inositol polyphosphate kinase Sulfotransfer_2 PF03567.14 KFP05933.1 - 6.3e-44 150.8 1.9 7.3e-44 150.6 1.9 1.0 1 0 0 1 1 1 1 Sulfotransferase family Complex1_LYR PF05347.15 KFP05933.1 - 0.063 13.3 1.1 0.17 12.0 0.1 2.3 3 0 0 3 3 3 0 Complex 1 protein (LYR family) Plus-3 PF03126.18 KFP05934.1 - 1.4e-36 125.3 0.1 1.4e-36 125.3 0.1 2.8 2 0 0 2 2 2 1 Plus-3 domain NUSAP PF16006.5 KFP05935.1 - 1.2e-100 337.1 24.4 1.2e-100 337.1 24.4 2.1 2 0 0 2 2 2 1 Nucleolar and spindle-associated protein EF-hand_7 PF13499.6 KFP05936.1 - 8.7e-18 64.5 3.1 3.7e-13 49.7 0.9 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP05936.1 - 1.7e-16 58.6 1.3 5.9e-07 28.9 0.3 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 KFP05936.1 - 1.7e-16 58.4 2.7 1.9e-06 27.0 0.4 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KFP05936.1 - 1.1e-07 31.6 1.6 3.2e-05 23.7 0.3 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP05936.1 - 2.1e-07 30.1 3.7 0.014 14.9 0.2 3.4 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 KFP05936.1 - 3.2e-05 24.2 0.0 0.0014 18.9 0.1 2.4 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region RST PF12174.8 KFP05936.1 - 0.00084 19.2 0.3 0.0039 17.1 0.0 2.2 3 0 0 3 3 3 1 RCD1-SRO-TAF4 (RST) plant domain EF-hand_4 PF12763.7 KFP05936.1 - 0.062 13.3 1.3 2.1 8.3 0.2 2.4 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand SNF2_N PF00176.23 KFP05937.1 - 7.4e-69 232.1 0.6 1.6e-68 231.0 0.6 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 KFP05937.1 - 3.6e-48 163.3 22.9 3.6e-48 163.3 22.9 3.9 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.31 KFP05937.1 - 5.1e-18 65.4 0.6 2.6e-17 63.1 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP05937.1 - 2.3e-06 27.7 11.7 5.1e-06 26.6 0.0 3.8 3 1 1 4 4 4 2 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KFP05937.1 - 1.7e-05 24.1 0.1 1.7e-05 24.1 0.1 3.7 5 0 0 5 5 5 1 Class II histone deacetylase complex subunits 2 and 3 EGF PF00008.27 KFP05938.1 - 4.7e-37 125.9 129.8 6.2e-09 36.0 9.9 8.9 8 0 0 8 8 8 7 EGF-like domain hEGF PF12661.7 KFP05938.1 - 6.2e-24 83.8 105.7 3.1e-07 30.8 6.5 9.9 9 0 0 9 9 9 8 Human growth factor-like EGF EGF_2 PF07974.13 KFP05938.1 - 6.8e-17 61.5 144.1 0.0049 17.2 11.9 8.6 8 0 0 8 8 8 8 EGF-like domain MNNL PF07657.13 KFP05938.1 - 1.6e-16 60.0 0.1 1.6e-16 60.0 0.1 4.4 4 1 2 6 6 6 1 N terminus of Notch ligand Laminin_EGF PF00053.24 KFP05938.1 - 8.2e-06 25.9 104.7 0.023 14.8 9.3 8.6 2 2 6 8 8 8 4 Laminin EGF domain EGF_CA PF07645.15 KFP05938.1 - 9.1e-05 22.6 7.6 9.1e-05 22.6 7.6 9.2 4 2 4 8 8 8 3 Calcium-binding EGF domain cEGF PF12662.7 KFP05938.1 - 0.00028 20.8 81.5 0.014 15.3 2.4 8.8 8 1 0 8 8 8 5 Complement Clr-like EGF-like EGF_3 PF12947.7 KFP05938.1 - 0.0008 19.6 7.6 0.0008 19.6 7.6 9.2 6 3 2 8 8 8 4 EGF domain DUF4381 PF14316.6 KFP05938.1 - 0.062 13.5 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Ly49 PF08391.10 KFP05938.1 - 0.077 13.4 0.1 0.18 12.2 0.1 1.6 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Pep3_Vps18 PF05131.14 KFP05939.1 - 2.4e-41 141.0 0.3 4.1e-40 137.0 0.1 2.5 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KFP05939.1 - 1.4e-12 47.7 17.2 1.1e-09 38.3 3.6 3.0 2 1 0 2 2 2 2 Region in Clathrin and VPS zf-C3HC4_2 PF13923.6 KFP05939.1 - 0.0014 18.4 1.3 0.0014 18.4 1.3 2.8 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KFP05939.1 - 0.0018 17.9 0.1 0.0018 17.9 0.1 2.4 3 0 0 3 3 2 1 Zinc-ribbon, C4HC2 type Vps39_2 PF10367.9 KFP05939.1 - 0.006 17.0 0.3 0.006 17.0 0.3 2.4 3 0 0 3 3 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.6 KFP05939.1 - 0.0062 16.5 0.3 0.027 14.4 0.3 2.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFP05939.1 - 0.015 15.4 0.5 0.054 13.5 0.5 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 KFP05939.1 - 0.02 15.2 0.5 0.02 15.2 0.5 2.7 2 0 0 2 2 2 0 Ring finger domain zf-RING_11 PF17123.5 KFP05939.1 - 0.024 14.4 0.9 0.024 14.4 0.9 2.6 2 0 0 2 2 2 0 RING-like zinc finger Nup54_57_C PF18570.1 KFP05939.1 - 0.034 13.7 1.6 0.099 12.2 0.6 2.2 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain zf-ANAPC11 PF12861.7 KFP05939.1 - 0.036 14.1 0.2 0.12 12.4 0.2 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KFP05939.1 - 0.059 13.7 0.2 0.059 13.7 0.2 2.2 2 0 0 2 2 1 0 RING-H2 zinc finger domain DUF5600 PF18150.1 KFP05939.1 - 0.07 13.7 0.1 0.66 10.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5600) DUF2229 PF09989.9 KFP05939.1 - 0.071 12.7 0.0 0.23 11.1 0.0 1.9 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) KNOX2 PF03791.13 KFP05939.1 - 0.073 12.6 1.0 0.22 11.1 0.3 2.2 2 0 0 2 2 2 0 KNOX2 domain Dzip-like_N PF13815.6 KFP05939.1 - 0.083 12.9 1.1 10 6.1 0.2 2.6 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF1664 PF07889.12 KFP05939.1 - 0.15 12.1 1.2 0.48 10.5 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-C4H2 PF10146.9 KFP05939.1 - 0.16 12.3 2.5 0.52 10.6 1.7 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein Exonuc_VII_S PF02609.16 KFP05939.1 - 3.1 7.9 6.2 32 4.7 1.1 3.5 3 0 0 3 3 3 0 Exonuclease VII small subunit Ras PF00071.22 KFP05940.1 - 2.7e-47 160.4 0.0 3.5e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP05940.1 - 1.7e-22 79.9 0.0 2.7e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP05940.1 - 2.1e-05 24.0 0.0 3.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP05940.1 - 0.046 13.8 0.0 0.081 13.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SNARE PF05739.19 KFP05940.1 - 0.11 12.5 0.2 0.21 11.6 0.2 1.4 1 0 0 1 1 1 0 SNARE domain AAA_7 PF12775.7 KFP05940.1 - 0.17 11.4 0.1 0.62 9.6 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Kunitz_BPTI PF00014.23 KFP05941.1 - 2.8e-32 110.7 21.4 1.3e-18 67.0 6.9 3.2 4 0 0 4 4 4 2 Kunitz/Bovine pancreatic trypsin inhibitor domain MANEC PF07502.14 KFP05941.1 - 6.4e-27 93.7 0.9 6.4e-27 93.7 0.9 2.9 3 1 1 4 4 4 1 MANEC domain Ldl_recept_a PF00057.18 KFP05941.1 - 1.6e-07 31.4 11.3 6.7e-07 29.4 11.3 2.2 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Orf78 PF06024.12 KFP05941.1 - 0.0014 18.9 0.1 0.0036 17.6 0.0 1.7 2 0 0 2 2 2 1 Orf78 (ac78) Y_Y_Y PF07495.13 KFP05941.1 - 0.0057 16.6 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Y_Y_Y domain REJ PF02010.15 KFP05941.1 - 0.008 15.0 0.1 0.012 14.4 0.1 1.2 1 0 0 1 1 1 1 REJ domain Chordopox_A13L PF05961.11 KFP05941.1 - 0.01 16.0 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein PKD PF00801.20 KFP05941.1 - 0.03 14.2 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 PKD domain DUF3377 PF11857.8 KFP05941.1 - 0.09 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) PP1_inhibitor PF05361.12 KFP05942.1 - 1.1e-14 54.6 2.9 1.1e-14 54.6 2.9 1.0 1 0 0 1 1 1 1 PKC-activated protein phosphatase-1 inhibitor FYVE PF01363.21 KFP05943.1 - 0.00064 19.8 12.3 0.00064 19.8 12.3 2.8 2 0 0 2 2 2 1 FYVE zinc finger Tho2 PF11262.8 KFP05943.1 - 1.9 7.6 3.7 1 8.5 0.1 2.0 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 UPF0444 PF15475.6 KFP05945.1 - 2.4e-44 149.5 12.0 2.7e-44 149.3 12.0 1.0 1 0 0 1 1 1 1 Transmembrane protein C12orf23, UPF0444 Sulfotransfer_1 PF00685.27 KFP05946.1 - 3e-58 197.4 0.0 3.7e-58 197.1 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP05946.1 - 3.5e-16 60.3 0.1 1.3e-10 42.0 0.0 2.9 3 0 0 3 3 3 2 Sulfotransferase family TPT PF03151.16 KFP05947.1 - 6.1e-23 81.6 9.7 7.1e-23 81.4 9.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFP05947.1 - 3e-09 37.2 28.5 4e-06 27.0 11.4 2.3 2 0 0 2 2 2 2 EamA-like transporter family FAD_binding_7 PF03441.14 KFP05948.1 - 3.3e-78 261.8 0.2 5.2e-78 261.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KFP05948.1 - 5.9e-26 91.4 0.0 1.4e-25 90.2 0.0 1.6 2 0 0 2 2 2 1 DNA photolyase Peripla_BP_6 PF13458.6 KFP05948.1 - 0.017 14.8 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein PID PF00640.23 KFP05949.1 - 3e-34 118.1 0.3 5.2e-34 117.3 0.3 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH3_9 PF14604.6 KFP05949.1 - 9.2e-14 51.0 0.3 2.3e-13 49.8 0.3 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP05949.1 - 2.1e-05 24.0 0.0 3.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain PID_2 PF14719.6 KFP05949.1 - 0.0016 18.3 0.1 0.0026 17.6 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH3_2 PF07653.17 KFP05949.1 - 0.009 15.7 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PTB PF08416.13 KFP05949.1 - 0.15 12.2 0.7 0.44 10.7 0.1 2.1 2 1 0 2 2 2 0 Phosphotyrosine-binding domain Pex16 PF08610.10 KFP05950.1 - 8.3e-67 225.6 3.0 9.2e-67 225.5 3.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) BESS PF02944.20 KFP05950.1 - 0.13 12.1 0.2 0.3 10.9 0.2 1.6 1 0 0 1 1 1 0 BESS motif Glyco_transf_49 PF13896.6 KFP05951.1 - 1.4e-58 198.8 2.6 3.4e-45 154.9 0.2 2.4 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_transf_8 PF01501.20 KFP05951.1 - 7.8e-19 68.2 0.7 1.2e-18 67.6 0.7 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KFP05951.1 - 9.5e-06 25.2 2.7 1.5e-05 24.6 2.7 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Herpes_BLRF2 PF05812.12 KFP05951.1 - 0.099 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein bZIP_2 PF07716.15 KFP05951.1 - 0.18 11.9 4.8 0.56 10.3 4.8 1.8 1 0 0 1 1 1 0 Basic region leucine zipper PHD PF00628.29 KFP05952.1 - 1.8e-12 46.9 6.6 3.9e-12 45.9 6.6 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KFP05952.1 - 0.0035 17.6 0.1 0.015 15.6 0.1 2.0 1 0 0 1 1 1 1 PHD-like zinc-binding domain C1_1 PF00130.22 KFP05952.1 - 0.005 16.7 2.0 0.005 16.7 2.0 1.9 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) AT_hook PF02178.19 KFP05952.1 - 0.0087 15.8 1.8 0.026 14.4 1.8 1.8 1 0 0 1 1 1 1 AT hook motif PHD_2 PF13831.6 KFP05952.1 - 0.023 14.2 1.0 0.023 14.2 1.0 1.9 2 0 0 2 2 2 0 PHD-finger zf-HC5HC2H_2 PF13832.6 KFP05952.1 - 0.04 14.1 0.1 0.14 12.3 0.1 1.9 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_2 PF13639.6 KFP05952.1 - 0.23 11.8 7.8 0.43 11.0 7.8 1.5 1 0 0 1 1 1 0 Ring finger domain Zf_RING PF16744.5 KFP05952.1 - 0.26 11.5 7.0 1.1 9.4 7.0 2.1 1 1 0 1 1 1 0 KIAA1045 RING finger Seryl_tRNA_N PF02403.22 KFP05952.1 - 0.36 11.1 15.6 0.86 9.9 4.5 2.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain OmpH PF03938.14 KFP05952.1 - 0.43 10.9 29.0 0.029 14.7 4.3 2.6 3 0 0 3 3 2 0 Outer membrane protein (OmpH-like) C1_2 PF03107.16 KFP05952.1 - 0.47 10.8 4.2 0.18 12.2 1.4 1.7 2 0 0 2 2 1 0 C1 domain Zn_ribbon_17 PF17120.5 KFP05952.1 - 1.1 8.9 5.2 1.1 8.9 3.4 1.8 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 KFP05952.1 - 1.4 9.3 4.6 2.8 8.3 4.6 1.6 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.6 KFP05952.1 - 2.1 8.4 6.7 1.8 8.5 3.0 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Leu_zip PF15294.6 KFP05952.1 - 4.6 6.7 20.0 4.6 6.7 7.7 2.3 2 0 0 2 2 2 0 Leucine zipper ADK_lid PF05191.14 KFP05952.1 - 5.4 7.1 8.4 1.2 9.2 3.6 2.4 2 1 0 2 2 2 0 Adenylate kinase, active site lid PhnA_Zn_Ribbon PF08274.12 KFP05952.1 - 5.9 6.9 6.0 6.4 6.8 0.2 2.4 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-PHD-like PF15446.6 KFP05952.1 - 6.1 6.4 11.0 0.12 11.9 0.9 3.0 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain DZR PF12773.7 KFP05952.1 - 6.2 6.9 7.2 2e+02 2.1 7.3 2.4 1 1 0 1 1 1 0 Double zinc ribbon GAS PF13851.6 KFP05952.1 - 7.2 5.9 27.1 0.1 11.9 5.4 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.21 KFP05954.1 - 3.7e-16 59.0 14.5 6.7e-16 58.1 14.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFP05954.1 - 7.1e-09 35.6 9.4 7.1e-09 35.6 9.4 2.3 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.17 KFP05954.1 - 3.7e-05 24.2 10.7 8e-05 23.1 10.7 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Spc29 PF17082.5 KFP05954.1 - 0.0079 16.1 0.4 0.014 15.2 0.4 1.3 1 0 0 1 1 1 1 Spindle Pole Component 29 LMBR1 PF04791.16 KFP05954.1 - 0.015 14.3 0.0 0.018 14.0 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein JMY PF15871.5 KFP05954.1 - 0.029 13.7 3.6 0.051 12.9 3.6 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Tcf25 PF04910.14 KFP05954.1 - 0.044 12.9 0.2 0.059 12.4 0.2 1.1 1 0 0 1 1 1 0 Transcriptional repressor TCF25 HAUS-augmin3 PF14932.6 KFP05954.1 - 0.046 13.3 5.5 0.083 12.5 5.5 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 APG6_N PF17675.1 KFP05954.1 - 0.054 14.0 7.2 0.12 12.9 7.2 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 KFP05954.1 - 0.065 13.3 11.0 0.11 12.5 11.0 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4337 PF14235.6 KFP05954.1 - 0.071 13.2 0.7 0.11 12.6 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Goodbye PF17109.5 KFP05954.1 - 0.087 13.3 0.2 0.18 12.2 0.2 1.6 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain Jnk-SapK_ap_N PF09744.9 KFP05954.1 - 0.13 12.5 6.7 0.25 11.6 6.7 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ADIP PF11559.8 KFP05954.1 - 0.16 12.1 11.5 0.27 11.3 11.5 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4404 PF14357.6 KFP05954.1 - 0.38 11.4 2.6 0.6 10.8 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF724 PF05266.14 KFP05954.1 - 0.39 10.5 4.6 0.76 9.6 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF3552 PF12072.8 KFP05954.1 - 0.61 9.5 9.2 0.95 8.8 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DAGK_acc PF00609.19 KFP05956.1 - 9.6e-47 159.3 0.0 1.7e-46 158.5 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KFP05956.1 - 4.3e-28 97.5 0.0 1e-27 96.3 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ank_2 PF12796.7 KFP05956.1 - 5.7e-13 49.3 0.0 1.2e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) C1_1 PF00130.22 KFP05956.1 - 1.9e-12 46.8 25.8 3e-10 39.8 14.0 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Ank_3 PF13606.6 KFP05956.1 - 4.2e-10 39.0 0.0 0.0006 20.1 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KFP05956.1 - 2e-08 34.6 0.1 0.00022 21.7 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP05956.1 - 3e-07 30.6 0.0 0.0027 18.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFP05956.1 - 3.1e-05 24.2 0.1 0.11 12.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat PTN_MK_N PF05196.13 KFP05957.1 - 1.3e-26 92.6 18.4 1.3e-26 92.6 18.4 2.4 2 1 0 2 2 2 1 PTN/MK heparin-binding protein family, N-terminal domain PTN_MK_C PF01091.18 KFP05957.1 - 2.1e-25 88.8 8.0 2.1e-25 88.8 8.0 2.8 2 1 1 3 3 3 1 PTN/MK heparin-binding protein family, C-terminal domain 7tm_1 PF00001.21 KFP05958.1 - 1.4e-74 250.8 7.7 1.9e-74 250.3 7.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP05958.1 - 8.6e-09 35.4 9.7 8.6e-09 35.4 9.7 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFP05958.1 - 5.9e-07 29.1 15.7 1.2e-05 24.8 7.3 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP05958.1 - 0.0002 21.2 8.6 0.0002 21.2 8.6 2.3 2 1 0 2 2 2 1 Olfactory receptor WD40 PF00400.32 KFP05959.1 - 4.2e-06 27.4 5.4 0.00031 21.5 0.5 4.3 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP05959.1 - 1.2e-05 25.6 0.0 0.1 12.9 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP05959.1 - 0.054 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A CAP_N PF01213.19 KFP05959.1 - 0.14 11.6 2.9 0.37 10.2 2.9 1.7 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Spt20 PF12090.8 KFP05959.1 - 1.2 8.6 6.5 0.32 10.6 1.7 2.5 3 0 0 3 3 3 0 Spt20 family DDE_Tnp_4 PF13359.6 KFP05960.1 - 6.5e-33 113.6 0.0 9.6e-33 113.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFP05960.1 - 7.5e-06 25.7 0.0 6.2e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 KFP05960.1 - 0.14 11.7 0.0 15 5.1 0.0 2.1 2 0 0 2 2 2 0 Transposase DDE domain ATG13 PF10033.9 KFP05961.1 - 3.3e-14 53.2 0.3 7.6e-07 29.1 0.3 3.1 1 1 1 2 2 2 2 Autophagy-related protein 13 RhoGAP PF00620.27 KFP05962.1 - 1.9e-44 151.2 0.2 4e-44 150.1 0.2 1.5 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 KFP05962.1 - 4.7e-40 136.9 1.2 4.7e-40 136.9 1.2 2.1 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KFP05962.1 - 1.2e-09 38.0 0.2 2.6e-09 37.0 0.2 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain zf-H2C2_2 PF13465.6 KFP05963.1 - 1.1e-17 63.5 11.5 8.9e-07 29.1 0.1 3.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFP05963.1 - 8.7e-12 44.8 9.6 2.4e-05 24.6 0.6 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP05963.1 - 2.2e-11 43.6 11.2 0.00013 22.5 0.5 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP05963.1 - 2.6e-10 40.3 2.5 0.00082 19.6 0.0 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP05963.1 - 1.9e-07 30.9 10.1 0.017 15.1 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-AN1 PF01428.16 KFP05963.1 - 7.2e-05 22.9 3.8 1.4 9.2 0.1 3.2 3 0 0 3 3 3 2 AN1-like Zinc finger zf_Hakai PF18408.1 KFP05963.1 - 0.00039 20.1 2.0 0.45 10.3 0.0 2.4 2 0 0 2 2 2 2 C2H2 Hakai zinc finger domain Zn_Tnp_IS1595 PF12760.7 KFP05963.1 - 0.00064 19.6 1.6 0.00064 19.6 1.6 2.1 2 0 0 2 2 2 1 Transposase zinc-ribbon domain zf-met PF12874.7 KFP05963.1 - 0.0011 19.3 5.8 0.023 15.1 0.2 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFP05963.1 - 0.004 16.9 8.9 0.029 14.1 0.3 3.1 3 0 0 3 3 3 1 zinc-finger C2H2-type zf_UBZ PF18439.1 KFP05963.1 - 0.0079 15.8 6.2 0.96 9.1 0.1 3.1 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger FYDLN_acid PF09538.10 KFP05963.1 - 0.0097 16.6 1.5 3.9 8.2 0.1 2.7 1 1 2 3 3 3 1 Protein of unknown function (FYDLN_acid) zf-C2HE PF16278.5 KFP05963.1 - 0.011 16.2 8.3 0.44 11.0 0.3 3.0 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-Di19 PF05605.12 KFP05963.1 - 0.021 15.1 4.8 0.11 12.8 1.3 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 KFP05963.1 - 0.033 14.5 1.0 0.038 14.3 0.8 1.3 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf_C2H2_ZHX PF18387.1 KFP05963.1 - 0.035 13.8 1.1 5.7 6.7 0.1 2.2 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-LYAR PF08790.11 KFP05963.1 - 0.039 13.9 7.2 0.89 9.5 0.1 3.1 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger HypA PF01155.19 KFP05963.1 - 0.041 13.9 0.8 0.041 13.9 0.8 1.8 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 KFP05963.1 - 0.13 12.2 8.6 1.3 9.0 4.4 3.0 2 1 0 2 2 2 0 zinc-ribbon domain zf-DNL PF05180.12 KFP05963.1 - 0.13 12.2 2.4 0.2 11.6 0.3 2.0 2 0 0 2 2 2 0 DNL zinc finger zf-RING_5 PF14634.6 KFP05963.1 - 0.15 12.0 5.3 0.64 10.0 2.0 2.5 2 1 0 2 2 2 0 zinc-RING finger domain DZR PF12773.7 KFP05963.1 - 0.25 11.4 6.9 2.9 8.0 6.9 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_2 PF12756.7 KFP05963.1 - 0.26 11.6 5.1 4.5 7.7 0.2 2.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 KFP05963.1 - 0.31 11.2 4.6 0.22 11.7 0.9 2.1 1 1 0 2 2 2 0 FYVE zinc finger zf_PR_Knuckle PF18445.1 KFP05963.1 - 0.36 10.7 2.9 21 5.0 0.1 3.0 3 0 0 3 3 3 0 PR zinc knuckle motif Zn-ribbon_8 PF09723.10 KFP05963.1 - 0.36 11.0 9.0 1.9 8.7 4.0 2.7 2 1 0 2 2 2 0 Zinc ribbon domain zf-Mss51 PF13824.6 KFP05963.1 - 0.41 10.8 7.9 2.1 8.5 0.1 2.8 1 1 2 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zinc-ribbons_6 PF07191.12 KFP05963.1 - 0.46 10.5 6.0 8.2 6.5 6.1 2.2 1 1 0 1 1 1 0 zinc-ribbons TF_Zn_Ribbon PF08271.12 KFP05963.1 - 0.73 9.4 7.3 4.3 6.9 1.7 2.6 2 1 0 2 2 2 0 TFIIB zinc-binding TFIIS_C PF01096.18 KFP05963.1 - 1.1 9.2 6.8 16 5.4 0.3 3.0 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) zf-HYPF PF07503.12 KFP05963.1 - 1.1 9.1 10.1 24 4.8 0.1 3.0 2 1 0 2 2 2 0 HypF finger DUF2197 PF09963.9 KFP05963.1 - 1.4 9.2 5.3 3.4 8.0 1.7 2.6 1 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) CpXC PF14353.6 KFP05963.1 - 2.1 8.4 7.1 0.73 9.9 0.2 2.7 1 1 2 3 3 3 0 CpXC protein zf-3CxxC_2 PF17180.4 KFP05963.1 - 2.4 9.0 8.9 28 5.5 8.9 2.6 1 1 0 1 1 1 0 Zinc-binding domain Elf1 PF05129.13 KFP05963.1 - 3.4 7.8 6.7 9.2 6.4 2.5 2.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Fer4_4 PF12800.7 KFP05963.1 - 4.7 8.0 8.4 7.9 7.3 0.3 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain zf-trcl PF13451.6 KFP05963.1 - 4.9 7.1 10.5 1e+02 2.9 0.1 3.0 2 1 0 2 2 2 0 Probable zinc-ribbon domain zf-CCHC_5 PF14787.6 KFP05963.1 - 6.1 6.6 8.8 5.9 6.7 0.2 2.7 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger MMS1_N PF10433.9 KFP05964.1 - 2.8e-118 395.6 0.0 6.9e-118 394.4 0.0 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KFP05964.1 - 6.6e-81 272.1 0.0 6.3e-80 268.9 0.0 2.4 2 0 0 2 2 2 1 CPSF A subunit region Dak2 PF02734.17 KFP05965.1 - 5.3e-47 160.0 2.0 7.9e-47 159.4 2.0 1.3 1 0 0 1 1 1 1 DAK2 domain Dak1 PF02733.17 KFP05965.1 - 1.9e-24 86.1 4.5 3.5e-12 45.8 0.1 3.5 3 1 1 4 4 4 3 Dak1 domain Cytochrom_B561 PF03188.16 KFP05966.1 - 5.9e-44 149.5 6.0 1.3e-43 148.4 6.0 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 KFP05966.1 - 0.65 10.1 16.5 0.06 13.5 6.4 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF4079) DUF2427 PF10348.9 KFP05966.1 - 0.86 9.4 6.9 0.42 10.4 1.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) Holin_9 PF16936.5 KFP05966.1 - 2.3 8.4 7.6 0.15 12.2 0.7 2.6 3 0 0 3 3 3 0 Putative holin TMEM138 PF14935.6 KFP05967.1 - 7.9e-34 116.9 1.1 8.7e-34 116.7 1.1 1.0 1 0 0 1 1 1 1 Transmembrane protein 138 Transmemb_17 PF09799.9 KFP05968.1 - 1.8e-15 57.4 1.1 1.9e-15 57.3 1.1 1.0 1 0 0 1 1 1 1 Predicted membrane protein InaF-motif PF15018.6 KFP05968.1 - 0.21 11.5 3.8 0.46 10.4 3.8 1.6 1 1 0 1 1 1 0 TRP-interacting helix RRM_1 PF00076.22 KFP05969.1 - 1.2e-06 28.3 0.0 3.4e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP05969.1 - 0.02 15.0 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif UCMA PF17085.5 KFP05969.1 - 0.087 12.8 5.3 0.17 11.9 5.3 1.5 1 0 0 1 1 1 0 Unique cartilage matrix associated protein PRP38_assoc PF12871.7 KFP05969.1 - 0.39 11.3 31.6 1 10.0 31.6 1.7 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Sdh5 PF03937.16 KFP05970.1 - 2.3e-13 49.9 0.1 3.2e-13 49.5 0.1 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase cNMP_binding PF00027.29 KFP05971.1 - 2.2e-51 171.8 0.1 8.3e-16 57.8 0.0 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Patatin PF01734.22 KFP05971.1 - 4.9e-22 79.1 0.1 1.1e-21 78.0 0.1 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase PKD_channel PF08016.12 KFP05972.1 - 4.7e-11 42.0 14.8 9.4e-11 41.0 14.8 1.5 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KFP05972.1 - 0.048 12.9 28.9 0.1 11.8 28.9 1.5 1 1 0 1 1 1 0 Ion transport protein GPP34 PF05719.11 KFP05973.1 - 8.3e-54 182.7 0.2 9.6e-54 182.5 0.2 1.0 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Peptidase_M15_2 PF05951.13 KFP05973.1 - 0.017 14.8 0.1 0.03 14.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) Lipase_GDSL_2 PF13472.6 KFP05974.1 - 1.5e-05 25.5 0.0 3e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 KFP05974.1 - 0.018 14.3 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 OSK domain NAPRTase_N PF17767.1 KFP05974.1 - 0.19 12.1 0.0 0.35 11.2 0.0 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain RVT_1 PF00078.27 KFP05975.1 - 4.9e-05 22.9 0.0 7.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MuF_C PF18819.1 KFP05975.1 - 0.1 12.6 0.1 0.16 12.0 0.1 1.3 1 1 0 1 1 1 0 Phage MuF-C-terminal domain DUF1725 PF08333.11 KFP05975.1 - 0.24 11.1 0.6 0.38 10.5 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) RVT_1 PF00078.27 KFP05976.1 - 0.0064 16.0 0.0 0.019 14.5 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) CotJB PF12652.7 KFP05976.1 - 0.093 13.0 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 CotJB protein dUTPase PF00692.19 KFP05977.1 - 7.6e-15 54.7 0.1 1.1e-14 54.2 0.1 1.2 1 0 0 1 1 1 1 dUTPase RVP PF00077.20 KFP05977.1 - 0.00072 19.8 0.2 0.0017 18.6 0.2 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease PC4 PF02229.16 KFP05978.1 - 1.2e-25 88.8 0.4 2.1e-25 88.1 0.4 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) QLQ PF08880.11 KFP05978.1 - 0.024 14.4 0.2 0.035 13.9 0.2 1.2 1 0 0 1 1 1 0 QLQ RNA_pol_Rpc4 PF05132.14 KFP05978.1 - 0.026 14.9 3.2 0.028 14.8 3.2 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DTHCT PF08070.11 KFP05978.1 - 0.11 13.3 13.8 0.18 12.5 13.8 1.4 1 0 0 1 1 1 0 DTHCT (NUC029) region dUTPase PF00692.19 KFP05979.1 - 3e-17 62.5 0.1 3.9e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 dUTPase DUF190 PF02641.15 KFP05979.1 - 0.014 15.7 0.2 0.2 12.0 0.1 2.5 1 1 2 3 3 3 0 Uncharacterized ACR, COG1993 TGF_beta PF00019.20 KFP05980.1 - 2.6e-29 102.3 2.0 2.6e-29 102.3 2.0 1.5 2 0 0 2 2 2 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFP05980.1 - 2.5e-18 66.7 0.1 3.4e-18 66.3 0.1 1.1 1 0 0 1 1 1 1 TGF-beta propeptide Tho1_MOS11_C PF18592.1 KFP05981.1 - 0.0026 17.5 11.0 0.28 11.0 1.7 3.7 2 2 1 3 3 3 3 Tho1/MOS11 C-terminal domain HCMV_UL139 PF12507.8 KFP05981.1 - 0.4 11.1 2.8 9.1 6.7 0.1 2.1 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein Jiv90 PF14901.6 KFP05982.1 - 1.7e-23 82.5 0.0 1.9e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 Cleavage inducing molecular chaperone G-alpha PF00503.20 KFP05984.1 - 1.6e-78 264.3 0.3 2e-78 264.1 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFP05984.1 - 3.2e-10 39.7 0.2 1.5e-06 27.8 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.6 KFP05984.1 - 0.039 13.7 0.0 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Roc PF08477.13 KFP05984.1 - 0.053 13.8 0.1 2.4 8.4 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KFP05984.1 - 0.093 12.1 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 KFP05984.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KFP05984.1 - 0.14 12.3 0.0 1.5 8.9 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase HIT PF01230.23 KFP05985.1 - 1.8e-10 41.4 0.0 1.9e-10 41.3 0.0 1.0 1 0 0 1 1 1 1 HIT domain dUTPase PF00692.19 KFP05986.1 - 1.4e-15 57.1 0.0 1.9e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 dUTPase RVP PF00077.20 KFP05986.1 - 0.022 15.0 0.1 0.081 13.2 0.0 1.9 2 1 0 2 2 2 0 Retroviral aspartyl protease RVT_1 PF00078.27 KFP05987.1 - 1.1e-33 116.7 0.0 1.4e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 KFP05987.1 - 2.6e-09 36.8 0.1 4.6e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase thumb domain rve PF00665.26 KFP05988.1 - 6.9e-27 94.0 0.1 1.2e-26 93.2 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_Zn PF02022.19 KFP05988.1 - 2.6e-14 52.9 0.2 6.1e-14 51.7 0.2 1.7 1 0 0 1 1 1 1 Integrase Zinc binding domain RNase_H PF00075.24 KFP05988.1 - 2e-09 37.8 2.4 2.4e-09 37.5 0.3 2.1 2 1 0 2 2 2 1 RNase H DDE_Tnp_IS240 PF13610.6 KFP05988.1 - 6.1e-05 23.3 0.0 0.00012 22.3 0.0 1.5 2 0 0 2 2 2 1 DDE domain rve_3 PF13683.6 KFP05988.1 - 0.084 12.7 0.0 0.27 11.0 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain CNOT1_HEAT PF16418.5 KFP05989.1 - 0.09 12.8 0.0 0.09 12.8 0.0 1.0 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 HEAT repeat CUB PF00431.20 KFP05992.1 - 1.7e-20 73.4 0.0 2.6e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 CUB domain PDGF PF00341.17 KFP05992.1 - 5.9e-11 42.5 4.3 1e-10 41.8 4.3 1.4 1 0 0 1 1 1 1 PDGF/VEGF domain AAA_6 PF12774.7 KFP05993.1 - 3.5e-131 437.0 0.1 1.1e-129 432.1 0.0 3.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KFP05993.1 - 1.9e-107 359.8 3.8 1.9e-107 359.8 3.8 5.4 6 0 0 6 6 4 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KFP05993.1 - 1.3e-72 243.5 1.8 1.3e-72 243.5 1.8 4.6 4 0 0 4 4 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 KFP05993.1 - 8.5e-56 189.2 0.3 2.5e-52 177.8 0.1 3.9 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KFP05993.1 - 2.5e-42 145.2 0.5 2.5e-42 145.2 0.5 3.3 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 KFP05993.1 - 5.4e-38 130.4 0.0 1.8e-37 128.7 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain DHC_N1 PF08385.12 KFP05993.1 - 1.1e-36 126.7 0.9 1.1e-36 126.7 0.9 4.6 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_5 PF07728.14 KFP05993.1 - 3.9e-36 124.1 0.0 1.3e-22 80.3 0.0 5.6 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 KFP05993.1 - 5e-35 120.2 0.1 5.1e-34 116.9 0.2 2.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_7 PF12775.7 KFP05993.1 - 2.1e-27 95.8 0.8 1.3e-24 86.7 0.0 3.5 3 0 0 3 3 3 1 P-loop containing dynein motor region MT PF12777.7 KFP05993.1 - 1.9e-26 92.9 14.8 2.5e-26 92.5 13.0 2.1 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_22 PF13401.6 KFP05993.1 - 1.8e-07 31.5 6.3 0.021 15.1 0.0 5.4 4 1 0 4 4 3 2 AAA domain RsgA_GTPase PF03193.16 KFP05993.1 - 4.2e-06 26.8 0.2 0.002 18.1 0.0 4.5 4 0 0 4 4 4 1 RsgA GTPase AAA_16 PF13191.6 KFP05993.1 - 1.7e-05 25.2 21.7 0.0048 17.3 0.0 7.9 8 1 1 9 9 8 2 AAA ATPase domain AAA PF00004.29 KFP05993.1 - 7.1e-05 23.2 5.5 0.61 10.5 0.0 5.4 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KFP05993.1 - 0.00027 20.7 1.3 0.033 13.9 0.0 3.4 3 0 0 3 3 2 1 AAA domain ABC_tran PF00005.27 KFP05993.1 - 0.00056 20.4 11.8 0.043 14.3 0.0 5.6 6 0 0 6 6 5 2 ABC transporter RNA_helicase PF00910.22 KFP05993.1 - 0.0026 18.1 0.4 1.8 9.0 0.1 4.3 4 0 0 4 4 3 1 RNA helicase ERM PF00769.19 KFP05993.1 - 0.0029 17.5 16.5 0.0029 17.5 16.5 4.8 5 0 0 5 5 5 2 Ezrin/radixin/moesin family AAA_29 PF13555.6 KFP05993.1 - 0.0069 16.1 0.1 1.4 8.7 0.0 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KFP05993.1 - 0.0071 16.1 0.3 2.2 8.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 KFP05993.1 - 0.009 16.3 0.2 0.38 11.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KFP05993.1 - 0.0097 16.5 0.6 8.9 6.9 0.1 5.0 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KFP05993.1 - 0.043 13.6 2.3 0.65 9.7 0.0 3.2 4 0 0 4 4 2 0 IstB-like ATP binding protein ATPase_2 PF01637.18 KFP05993.1 - 0.1 12.5 0.0 0.1 12.5 0.0 5.2 6 0 0 6 6 5 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KFP05993.1 - 0.33 11.1 2.7 0.79 9.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 KFP05993.1 - 0.5 10.8 0.0 0.5 10.8 0.0 8.7 9 0 0 9 9 8 0 AAA domain NACHT PF05729.12 KFP05993.1 - 1.3 8.9 5.1 30 4.5 0.2 4.3 4 0 0 4 4 3 0 NACHT domain DUF2968 PF11180.8 KFP05993.1 - 9.9 5.8 28.6 0.32 10.6 9.1 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Cullin_binding PF03556.15 KFP05994.1 - 2.5e-30 105.4 4.5 3.6e-30 104.9 4.5 1.2 1 0 0 1 1 1 1 Cullin binding Peptidase_M10 PF00413.24 KFP05995.1 - 3.1e-65 218.8 0.0 4.9e-65 218.2 0.0 1.3 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 KFP05995.1 - 3.5e-41 138.9 4.4 1.1e-13 50.8 0.0 4.4 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 KFP05995.1 - 2.4e-11 43.7 0.0 4.3e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.24 KFP05995.1 - 0.0078 15.8 0.1 3.3 7.3 0.0 2.5 3 0 0 3 3 3 2 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 KFP05995.1 - 0.013 16.0 0.0 0.033 14.7 0.0 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP05995.1 - 0.043 13.5 0.1 0.088 12.4 0.0 1.5 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 KFP05995.1 - 0.056 12.7 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Met-zincin Reprolysin_5 PF13688.6 KFP05995.1 - 0.066 13.4 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 MerR_2 PF13591.6 KFP05995.1 - 0.13 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 MerR HTH family regulatory protein Peptidase_M10 PF00413.24 KFP05996.1 - 1.1e-61 207.3 0.0 2.3e-61 206.2 0.0 1.6 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 KFP05996.1 - 2.1e-44 149.2 9.9 4.4e-15 55.4 0.1 4.4 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 KFP05996.1 - 1.5e-12 47.5 0.0 2.7e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.24 KFP05996.1 - 0.0055 16.3 0.1 3.1 7.3 0.2 2.3 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 KFP05996.1 - 0.0082 16.7 0.1 0.02 15.4 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFP05996.1 - 0.048 13.8 0.1 0.093 12.9 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF4953 PF16313.5 KFP05996.1 - 0.071 12.3 0.9 0.1 11.8 0.2 1.6 2 0 0 2 2 2 0 Met-zincin Peptidase_M57 PF12388.8 KFP05996.1 - 0.17 11.4 0.2 0.33 10.5 0.2 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.6 KFP05996.1 - 0.17 11.5 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFP05997.1 - 5.5e-60 201.8 0.1 1.2e-59 200.6 0.0 1.6 2 0 0 2 2 2 1 Matrixin Hemopexin PF00045.19 KFP05997.1 - 9.3e-36 121.5 9.7 1.6e-12 47.1 0.6 4.4 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 KFP05997.1 - 3.5e-09 36.7 0.7 2.7e-08 33.9 0.1 2.5 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Reprolysin_3 PF13582.6 KFP05997.1 - 3.3e-05 24.4 0.0 0.00016 22.2 0.0 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 KFP05997.1 - 0.00038 20.1 0.8 0.61 9.7 0.2 2.6 3 0 0 3 3 3 2 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.6 KFP05997.1 - 0.00061 20.0 0.0 0.00093 19.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KFP05997.1 - 0.0028 17.3 0.0 0.0059 16.3 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 KFP05997.1 - 0.015 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 DUF4953 PF16313.5 KFP05997.1 - 0.054 12.7 0.2 0.13 11.5 0.2 1.5 1 0 0 1 1 1 0 Met-zincin Peptidase_M66 PF10462.9 KFP05997.1 - 0.088 11.7 0.2 0.16 10.9 0.2 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M57 PF12388.8 KFP05997.1 - 0.19 11.3 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Metallopep PF12044.8 KFP05997.1 - 0.19 10.3 0.0 0.31 9.6 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M10 PF00413.24 KFP05998.1 - 7.5e-60 201.3 0.0 1.2e-59 200.7 0.0 1.3 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 KFP05998.1 - 2.6e-43 145.7 5.6 8.3e-13 48.1 0.1 4.3 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 KFP05998.1 - 3.3e-16 59.2 0.5 1.3e-15 57.3 0.2 2.1 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Astacin PF01400.24 KFP05998.1 - 0.0018 18.0 0.2 0.37 10.4 0.1 2.3 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 KFP05998.1 - 0.004 17.7 0.1 0.0076 16.8 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 KFP05998.1 - 0.011 15.0 0.3 0.018 14.3 0.3 1.2 1 0 0 1 1 1 0 Met-zincin Reprolysin_4 PF13583.6 KFP05998.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFP05998.1 - 0.025 14.7 0.1 0.04 14.1 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 KFP05998.1 - 0.038 12.9 0.1 0.07 12.1 0.1 1.4 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M54 PF07998.11 KFP05998.1 - 0.039 13.9 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 Reprolysin_2 PF13574.6 KFP05998.1 - 0.087 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 KFP05998.1 - 0.19 10.3 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M10 PF00413.24 KFP05999.1 - 1.1e-61 207.3 0.0 1.5e-61 206.8 0.0 1.2 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.18 KFP05999.1 - 5.2e-11 42.6 0.0 9.3e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.24 KFP05999.1 - 0.00027 20.6 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) DUF4953 PF16313.5 KFP05999.1 - 0.0047 16.2 0.1 0.007 15.6 0.1 1.2 1 0 0 1 1 1 1 Met-zincin Reprolysin_4 PF13583.6 KFP05999.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 KFP05999.1 - 0.023 15.2 0.7 0.039 14.5 0.7 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFP05999.1 - 0.038 14.1 0.1 0.06 13.5 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 KFP05999.1 - 0.13 11.2 0.1 0.2 10.6 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_2 PF13574.6 KFP05999.1 - 0.23 11.3 0.0 0.36 10.7 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like MGC-24 PF05283.11 KFP06000.1 - 5.3e-09 36.7 8.2 5.8e-09 36.5 8.2 1.1 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin FSA_C PF10479.9 KFP06000.1 - 0.18 9.9 8.0 0.17 10.0 8.0 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Mucin PF01456.17 KFP06000.1 - 6.6 6.7 21.9 8.3 6.4 21.9 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein BIR PF00653.21 KFP06001.1 - 1.1e-64 215.0 12.4 3e-21 75.9 0.8 3.9 4 0 0 4 4 4 3 Inhibitor of Apoptosis domain CARD PF00619.21 KFP06001.1 - 5.3e-22 77.7 0.4 1.3e-21 76.4 0.4 1.7 1 0 0 1 1 1 1 Caspase recruitment domain zf-C3HC4_3 PF13920.6 KFP06001.1 - 1.3e-14 53.8 8.2 1.3e-14 53.8 8.2 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP06001.1 - 2.8e-07 30.3 7.9 2.8e-07 30.3 7.9 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFP06001.1 - 0.0056 16.6 7.1 0.0056 16.6 7.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain DUF2039 PF10217.9 KFP06001.1 - 0.11 12.9 4.4 0.34 11.3 4.4 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) RNA_pol_N PF01194.17 KFP06001.1 - 0.18 12.1 6.8 4.2 7.7 0.0 3.3 3 0 0 3 3 3 0 RNA polymerases N / 8 kDa subunit zf-RING_UBOX PF13445.6 KFP06001.1 - 0.29 11.2 6.2 0.69 10.0 3.5 2.7 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFP06001.1 - 0.5 10.3 13.8 0.21 11.4 9.9 2.6 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) WW PF00397.26 KFP06002.1 - 7.3e-10 38.8 0.3 1.6e-09 37.7 0.3 1.6 1 0 0 1 1 1 1 WW domain TFIIA PF03153.13 KFP06002.1 - 0.18 11.8 10.2 0.22 11.5 10.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4498 PF14926.6 KFP06003.1 - 1.4e-102 342.3 4.6 1.5e-102 342.1 4.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) K1377 PF15352.6 KFP06004.1 - 9.7e-219 729.2 52.3 1.3e-218 728.8 52.3 1.1 1 0 0 1 1 1 1 Susceptibility to monomelic amyotrophy Hormone_recep PF00104.30 KFP06005.1 - 1.1e-27 97.0 7.3 1.8e-27 96.3 7.3 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFP06005.1 - 1.6e-26 92.5 15.7 1.6e-26 92.5 15.7 1.5 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Prog_receptor PF02161.15 KFP06005.1 - 2.6e-19 69.4 10.0 1.2e-18 67.2 10.0 1.8 1 1 0 1 1 1 1 Progesterone receptor BAR_3 PF16746.5 KFP06006.1 - 6.6e-47 160.2 19.4 6e-40 137.4 13.1 2.3 1 1 1 2 2 2 2 BAR domain of APPL family RhoGAP PF00620.27 KFP06006.1 - 1.9e-40 138.2 0.3 1e-39 135.8 0.1 2.2 2 0 0 2 2 2 1 RhoGAP domain SH3_9 PF14604.6 KFP06006.1 - 8.3e-09 35.2 0.0 1.7e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP06006.1 - 1.2e-05 24.8 0.0 2.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP06006.1 - 0.063 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain DUF4211 PF13926.6 KFP06009.1 - 8.3e-33 113.5 1.0 8.3e-33 113.5 1.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) DUF4196 PF13846.6 KFP06009.1 - 1.3e-14 54.4 0.8 1.3e-14 54.4 0.8 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4196) DUF2185 PF09951.9 KFP06009.1 - 0.0061 16.4 0.8 0.048 13.5 0.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2185) Myotub-related PF06602.14 KFP06012.1 - 1.2e-153 511.2 0.0 1.5e-153 510.9 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 KFP06012.1 - 7.5e-19 67.7 0.0 1.6e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Y_phosphatase PF00102.27 KFP06012.1 - 0.00027 20.6 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase 3-PAP PF12578.8 KFP06012.1 - 0.00099 18.9 0.1 0.0025 17.6 0.1 1.7 1 0 0 1 1 1 1 Myotubularin-associated protein DSPc PF00782.20 KFP06012.1 - 0.0043 16.8 0.0 0.0092 15.8 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP06012.1 - 0.033 14.2 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family NYD-SP28_assoc PF14775.6 KFP06012.1 - 0.063 13.4 5.3 0.84 9.8 0.9 3.3 3 0 0 3 3 3 0 Sperm tail C-terminal domain Cep57_CLD PF14073.6 KFP06013.1 - 1.1e-66 224.2 39.1 1.1e-66 224.2 39.1 2.4 2 0 0 2 2 2 1 Centrosome localisation domain of Cep57 Cep57_MT_bd PF06657.13 KFP06013.1 - 3.1e-21 75.6 5.0 3.1e-21 75.6 5.0 4.4 3 1 1 4 4 4 1 Centrosome microtubule-binding domain of Cep57 FAM76 PF16046.5 KFP06014.1 - 1.7e-104 349.4 39.0 1.9e-104 349.2 39.0 1.0 1 0 0 1 1 1 1 FAM76 protein Macoilin PF09726.9 KFP06014.1 - 0.14 10.6 25.7 0.22 10.0 25.7 1.3 1 0 0 1 1 1 0 Macoilin family OmpH PF03938.14 KFP06014.1 - 0.31 11.4 11.6 0.79 10.1 11.6 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MPS2 PF17060.5 KFP06014.1 - 0.59 9.3 13.0 0.98 8.6 11.4 2.0 1 1 1 2 2 2 0 Monopolar spindle protein 2 Kinesin_assoc PF16183.5 KFP06014.1 - 0.83 9.8 6.0 0.37 10.9 1.3 2.1 2 0 0 2 2 2 0 Kinesin-associated DUF3552 PF12072.8 KFP06014.1 - 2.3 7.6 22.5 0.023 14.1 13.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Metal_resist PF13801.6 KFP06014.1 - 2.4 8.4 8.2 13 6.0 3.1 2.3 2 0 0 2 2 2 0 Heavy-metal resistance NicO PF03824.16 KFP06014.1 - 2.7 7.3 9.5 4.5 6.5 9.5 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein DUF2614 PF11023.8 KFP06014.1 - 3.2 7.9 8.6 1.4 9.0 1.2 2.3 1 1 1 2 2 2 0 Zinc-ribbon containing domain DZR PF12773.7 KFP06014.1 - 3.9 7.6 24.6 7.7 6.6 14.0 2.6 1 1 1 2 2 2 0 Double zinc ribbon Innate_immun PF12782.7 KFP06014.1 - 7 6.1 12.9 11 5.4 12.9 1.3 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family bZIP_2 PF07716.15 KFP06014.1 - 9.5 6.4 10.6 3.2 7.9 4.2 2.6 2 0 0 2 2 2 0 Basic region leucine zipper Cwf_Cwc_15 PF04889.12 KFP06016.1 - 3e-77 259.7 21.2 4e-77 259.3 21.2 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein UPF0524 PF15823.5 KFP06016.1 - 0.41 10.0 1.9 0.4 10.0 0.7 1.5 1 1 0 1 1 1 0 UPF0524 of C3orf70 Angiomotin_C PF12240.8 KFP06017.1 - 5e-92 307.1 37.0 3.2e-91 304.5 14.8 3.4 2 1 1 3 3 3 2 Angiomotin C terminal DUF1216 PF06746.11 KFP06017.1 - 0.25 11.3 3.4 0.8 9.7 3.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) MatP_C PF17414.2 KFP06017.1 - 0.62 10.3 2.9 3.6 7.8 0.9 3.1 2 0 0 2 2 2 0 MatP C-terminal ribbon-helix-helix domain NPV_P10 PF05531.12 KFP06017.1 - 0.99 9.9 4.6 0.97 9.9 1.4 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PilO PF04350.13 KFP06017.1 - 1.2 9.3 10.2 6 7.0 0.6 2.9 2 0 0 2 2 2 0 Pilus assembly protein, PilO GIT1_C PF12205.8 KFP06017.1 - 2 8.5 8.3 13 5.9 4.8 2.7 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term JAKMIP_CC3 PF16034.5 KFP06017.1 - 3.3 7.6 36.5 1.4 8.8 21.5 3.1 2 1 1 3 3 3 0 JAKMIP CC3 domain Lebercilin PF15619.6 KFP06017.1 - 4.4 6.9 44.6 0.053 13.2 25.2 3.8 1 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease CCDC144C PF14915.6 KFP06017.1 - 6.6 5.7 40.5 1.8 7.6 4.3 3.9 1 1 2 3 3 3 0 CCDC144C protein coiled-coil region Ank_4 PF13637.6 KFP06018.1 - 1.1e-31 108.7 4.7 1.7e-14 54.0 0.2 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP06018.1 - 3.4e-30 104.5 8.4 9.7e-18 64.6 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFP06018.1 - 4.1e-26 90.3 4.3 2.3e-09 37.3 0.0 4.5 4 1 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KFP06018.1 - 3e-23 79.4 1.9 1.1e-06 28.5 0.0 4.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KFP06018.1 - 9.8e-23 79.9 7.3 8.4e-10 38.7 0.1 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Mre11_DNA_bind PF04152.14 KFP06019.1 - 2.2e-48 164.8 0.7 2.2e-48 164.8 0.7 2.2 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KFP06019.1 - 1.7e-15 58.1 2.4 3.3e-15 57.1 2.4 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFP06019.1 - 3e-06 27.5 0.1 3.8e-05 24.0 0.1 2.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain APG6_N PF17675.1 KFP06019.1 - 2.7 8.5 14.6 6.6 7.3 14.6 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region CdiI_2 PF18593.1 KFP06019.1 - 4.1 8.1 6.1 6.6 7.5 2.0 3.1 1 1 1 3 3 3 0 CdiI immunity protein DUF1764 PF08576.10 KFP06019.1 - 4.7 8.2 7.5 14 6.7 7.5 1.8 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) 7tm_1 PF00001.21 KFP06020.1 - 1.1e-51 175.7 25.2 1.5e-51 175.2 25.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP06020.1 - 4.2e-18 65.7 24.7 5.3e-18 65.3 24.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP06020.1 - 1e-05 25.4 16.7 1.4e-05 24.9 16.7 1.3 1 1 0 1 1 1 1 Olfactory receptor DUF2109 PF09882.9 KFP06020.1 - 0.34 11.0 6.0 0.38 10.8 1.6 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) DUF2116 PF09889.9 KFP06020.1 - 0.6 10.1 3.2 0.65 10.0 0.1 2.6 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Innexin PF00876.18 KFP06021.1 - 2e-16 60.3 4.1 2e-16 60.3 4.1 1.7 1 1 1 2 2 2 1 Innexin DUF2207 PF09972.9 KFP06021.1 - 1.4 7.6 7.5 4.9 5.8 2.9 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) L6_membrane PF05805.12 KFP06022.1 - 1.4e-67 226.9 19.8 1.6e-67 226.8 19.8 1.0 1 0 0 1 1 1 1 L6 membrane protein V-set PF07686.17 KFP06023.1 - 4.1e-06 26.9 0.1 5.6e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Receptor_2B4 PF11465.8 KFP06023.1 - 0.00014 22.0 0.1 0.00024 21.3 0.1 1.3 1 0 0 1 1 1 1 Natural killer cell receptor 2B4 I-set PF07679.16 KFP06023.1 - 0.00054 20.0 0.2 0.0026 17.8 0.2 2.0 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP06023.1 - 0.0064 17.1 0.3 0.026 15.1 0.3 1.9 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP06023.1 - 0.025 14.8 0.3 0.042 14.0 0.3 1.6 1 1 0 1 1 1 0 Immunoglobulin domain Med17 PF10156.9 KFP06024.1 - 1.2e-08 34.1 0.5 1.8e-08 33.5 0.5 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Thioredoxin_12 PF18400.1 KFP06024.1 - 0.043 13.7 1.1 0.076 12.9 0.1 1.9 2 0 0 2 2 2 0 Thioredoxin-like domain DUF1907 PF08925.11 KFP06025.1 - 6.5e-122 406.4 0.0 7.3e-122 406.2 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) TAF1D PF15333.6 KFP06026.1 - 6.4e-67 225.5 17.4 1.8e-66 224.0 17.4 1.7 1 1 0 1 1 1 1 TATA box-binding protein-associated factor 1D FAM199X PF15814.5 KFP06026.1 - 2.7 7.0 6.8 3.5 6.6 6.8 1.1 1 0 0 1 1 1 0 Protein family FAM199X ALMS_motif PF15309.6 KFP06027.1 - 7e-16 58.9 18.4 7e-16 58.9 18.4 1.4 2 0 0 2 2 2 1 ALMS motif MCCD1 PF15707.5 KFP06029.1 - 0.012 16.0 3.4 0.015 15.7 3.4 1.3 1 0 0 1 1 1 0 Mitochondrial coiled-coil domain protein 1 Fmp27_WPPW PF10359.9 KFP06029.1 - 0.057 12.3 2.5 0.059 12.2 2.5 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF530 PF04409.12 KFP06030.1 - 0.11 10.9 2.1 0.12 10.7 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF530) ABC_tran_Xtn PF12848.7 KFP06030.1 - 0.35 10.9 8.0 0.71 9.9 8.0 1.4 1 0 0 1 1 1 0 ABC transporter CPSase_L_D3 PF02787.19 KFP06031.1 - 0.021 15.2 0.4 0.035 14.4 0.4 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain FUSC-like PF12805.7 KFP06031.1 - 0.039 13.0 5.5 0.044 12.8 5.5 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS ISG65-75 PF11727.8 KFP06031.1 - 0.066 12.4 6.3 0.074 12.3 6.3 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein Kri1 PF05178.12 KFP06031.1 - 5.9 7.5 11.8 7.8 7.1 11.7 1.3 1 1 0 1 1 1 0 KRI1-like family DUF4519 PF15012.6 KFP06032.1 - 6.8e-29 99.8 4.5 7.5e-29 99.7 4.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4519) DUF4448 PF14610.6 KFP06032.1 - 0.00044 20.1 0.1 0.00047 20.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Orf78 PF06024.12 KFP06032.1 - 0.00078 19.7 0.0 0.00081 19.7 0.0 1.0 1 0 0 1 1 1 1 Orf78 (ac78) DUF2232 PF09991.9 KFP06032.1 - 0.0024 17.1 0.0 0.0027 16.9 0.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2232) FTCD_C PF04961.12 KFP06032.1 - 0.0036 17.1 0.1 0.0038 17.0 0.1 1.0 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase CrgA PF06781.12 KFP06032.1 - 0.0092 16.0 0.2 0.01 15.9 0.2 1.0 1 0 0 1 1 1 1 Cell division protein CrgA DUF2208 PF09973.9 KFP06032.1 - 0.016 14.9 0.0 0.016 14.9 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Vma12 PF11712.8 KFP06032.1 - 0.031 14.3 0.0 0.034 14.2 0.0 1.1 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF5305 PF17231.2 KFP06032.1 - 0.039 13.4 0.1 0.041 13.3 0.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5305) TMEM154 PF15102.6 KFP06032.1 - 0.048 13.6 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family EMC3_TMCO1 PF01956.16 KFP06032.1 - 0.051 13.3 0.1 0.057 13.1 0.1 1.0 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF3671 PF12420.8 KFP06032.1 - 0.051 13.6 0.0 0.056 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF3899 PF13038.6 KFP06032.1 - 0.062 13.8 0.0 0.063 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) DUF515 PF04415.12 KFP06032.1 - 0.063 11.7 0.2 0.064 11.6 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DotU PF09850.9 KFP06032.1 - 0.065 13.0 0.1 0.069 12.9 0.1 1.0 1 0 0 1 1 1 0 Type VI secretion system protein DotU DUF2116 PF09889.9 KFP06032.1 - 0.13 12.3 0.2 0.19 11.7 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Zn-C2H2_12 PF18112.1 KFP06033.1 - 0.15 12.5 0.0 0.79 10.2 0.0 1.9 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain 7tm_1 PF00001.21 KFP06034.1 - 1.4e-42 145.8 25.5 1.7e-42 145.5 25.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP06034.1 - 1.6e-08 34.6 25.1 3.4e-08 33.5 25.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP06034.1 - 0.077 12.7 16.5 3.4 7.3 16.5 2.3 1 1 0 1 1 1 0 Olfactory receptor Git3 PF11710.8 KFP06034.1 - 1.7 8.4 25.1 0.51 10.1 16.4 2.2 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 Cadherin PF00028.17 KFP06035.1 - 0 1179.0 68.7 1.9e-22 79.5 0.0 25.6 26 0 0 26 26 25 25 Cadherin domain Laminin_G_2 PF02210.24 KFP06035.1 - 7.6e-24 84.7 0.6 1.2e-22 80.8 0.1 3.3 4 0 0 4 4 2 1 Laminin G domain Cadherin_2 PF08266.12 KFP06035.1 - 4.5e-19 68.1 0.3 1.2 9.0 0.0 13.1 13 0 0 13 13 13 3 Cadherin-like RET_CLD1 PF17756.1 KFP06035.1 - 6.4e-18 65.2 0.4 0.014 15.6 0.0 11.3 13 0 0 13 13 13 2 RET Cadherin like domain 1 Laminin_G_1 PF00054.23 KFP06035.1 - 7.3e-17 61.8 0.0 5.1e-16 59.1 0.0 2.5 2 0 0 2 2 2 1 Laminin G domain Cadherin_3 PF16184.5 KFP06035.1 - 7e-15 55.0 56.4 0.19 11.8 0.2 17.2 19 0 0 19 19 19 7 Cadherin-like EGF PF00008.27 KFP06035.1 - 3.2e-11 43.3 55.3 0.00022 21.5 9.0 4.7 4 0 0 4 4 4 3 EGF-like domain EGF_CA PF07645.15 KFP06035.1 - 3.4e-05 24.0 10.7 3.4e-05 24.0 10.7 4.6 3 1 1 4 4 3 1 Calcium-binding EGF domain RMI1_C PF16099.5 KFP06035.1 - 0.00014 21.7 0.6 13 5.6 0.0 5.7 6 0 0 6 6 6 1 Recq-mediated genome instability protein 1, C-terminal OB-fold hEGF PF12661.7 KFP06035.1 - 0.00055 20.5 46.6 0.011 16.4 7.8 4.9 4 0 0 4 4 4 2 Human growth factor-like EGF REJ PF02010.15 KFP06035.1 - 0.083 11.7 2.8 8.3 5.1 0.1 4.1 4 0 0 4 4 4 0 REJ domain Big_9 PF17963.1 KFP06035.1 - 0.085 13.6 0.0 0.085 13.6 0.0 17.1 17 0 0 17 17 17 0 Bacterial Ig domain Cadherin_4 PF17803.1 KFP06035.1 - 0.11 13.1 98.9 0.19 12.4 0.4 15.5 18 0 0 18 18 17 0 Bacterial cadherin-like domain CHORD PF04968.12 KFP06036.1 - 6.5e-47 158.1 19.5 7.1e-27 93.9 8.1 2.9 3 0 0 3 3 3 2 CHORD CS PF04969.16 KFP06036.1 - 5.1e-13 49.8 0.2 1e-12 48.9 0.2 1.5 1 0 0 1 1 1 1 CS domain TFR_dimer PF04253.15 KFP06037.1 - 2.8e-36 124.3 0.0 6.2e-36 123.2 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KFP06037.1 - 6.4e-19 68.4 0.0 2.6e-18 66.5 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 KFP06037.1 - 9.5e-13 48.0 0.0 2.2e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 PA domain TFR_dimer PF04253.15 KFP06038.1 - 9.4e-37 125.8 0.1 2.1e-36 124.7 0.1 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KFP06038.1 - 2.5e-18 66.5 0.0 9.2e-18 64.6 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 KFP06038.1 - 5.8e-13 48.7 0.0 1.2e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 PA domain PPR_3 PF13812.6 KFP06038.1 - 0.011 15.8 0.0 0.03 14.4 0.0 1.7 1 0 0 1 1 1 0 Pentatricopeptide repeat domain Ferric_reduct PF01794.19 KFP06039.1 - 2.8e-23 82.4 5.4 2.8e-23 82.4 5.4 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KFP06039.1 - 1.4e-22 80.5 0.0 5.1e-21 75.4 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFP06039.1 - 1.2e-15 57.5 0.0 2.9e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KFP06039.1 - 0.019 15.6 0.0 0.14 12.9 0.0 2.3 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Heliorhodopsin PF18761.1 KFP06039.1 - 0.021 14.2 0.4 0.047 13.0 0.3 1.6 1 1 0 1 1 1 0 Heliorhodopsin Ni_hydr_CYTB PF01292.20 KFP06039.1 - 0.048 13.3 3.2 3.3 7.3 0.5 2.3 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 Tyrosinase PF00264.20 KFP06040.1 - 6.5e-40 137.8 1.2 6.5e-40 137.8 1.2 1.6 2 0 0 2 2 2 1 Common central domain of tyrosinase Laminin_EGF PF00053.24 KFP06040.1 - 0.0017 18.5 3.4 0.0017 18.5 3.4 2.3 2 0 0 2 2 2 1 Laminin EGF domain Ldr_toxin PF13940.6 KFP06040.1 - 0.03 14.4 1.5 0.063 13.3 1.5 1.5 1 0 0 1 1 1 0 Toxin Ldr, type I toxin-antitoxin system RICTOR_M PF14666.6 KFP06040.1 - 0.098 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain LapA_dom PF06305.11 KFP06040.1 - 3.5 7.5 4.2 0.59 10.0 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain 7tm_3 PF00003.22 KFP06041.1 - 9.2e-58 195.8 24.8 1.3e-57 195.2 24.8 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 KFP06041.1 - 6.4e-46 157.1 0.0 8.8e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region GluR_Homer-bdg PF10606.9 KFP06041.1 - 1.4e-20 73.2 12.1 5.3e-20 71.4 12.1 2.1 1 0 0 1 1 1 1 Homer-binding domain of metabotropic glutamate receptor NCD3G PF07562.14 KFP06041.1 - 3e-16 59.1 14.0 5.9e-16 58.2 14.0 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR DUF5438 PF17506.2 KFP06041.1 - 0.58 10.5 3.3 0.29 11.5 0.5 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5438) Ras PF00071.22 KFP06042.1 - 6.6e-42 142.9 0.0 7.9e-42 142.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP06042.1 - 6.7e-29 100.6 0.0 9.3e-29 100.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP06042.1 - 5.4e-10 39.0 0.1 6.1e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFP06042.1 - 1.1e-06 28.2 0.0 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TniB PF05621.11 KFP06042.1 - 0.0029 17.0 0.0 0.01 15.3 0.0 1.9 1 1 1 2 2 2 1 Bacterial TniB protein MMR_HSR1 PF01926.23 KFP06042.1 - 0.0048 17.0 0.0 0.0071 16.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 KFP06042.1 - 0.012 15.2 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KFP06042.1 - 0.016 15.5 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KFP06042.1 - 0.026 14.2 0.0 0.66 9.7 0.0 2.4 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 KFP06042.1 - 0.15 12.1 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RVT_1 PF00078.27 KFP06043.1 - 0.035 13.6 0.0 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) TMEM135_C_rich PF15982.5 KFP06044.1 - 2.3e-45 154.5 1.4 2.3e-45 154.5 1.4 2.1 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 Tim17 PF02466.19 KFP06044.1 - 1.9e-08 34.7 1.4 9.8e-08 32.4 0.2 2.4 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Frizzled PF01534.17 KFP06045.1 - 4.1e-126 420.4 23.7 1.2e-125 418.9 23.7 1.6 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 KFP06045.1 - 8.6e-14 52.1 1.2 1.7e-13 51.2 1.2 1.5 1 0 0 1 1 1 1 Fz domain DUF5083 PF16890.5 KFP06045.1 - 0.0052 16.5 0.5 0.0099 15.6 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5083) DUF3852 PF12963.7 KFP06045.1 - 5.6 7.4 9.3 0.69 10.3 2.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3852) Trypsin PF00089.26 KFP06046.1 - 9e-11 42.0 0.1 4.9e-10 39.6 0.1 2.2 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFP06046.1 - 6e-08 33.7 0.0 1e-07 32.9 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Malic_M PF03949.15 KFP06047.1 - 1.2e-102 342.6 0.4 1.5e-102 342.3 0.4 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KFP06047.1 - 3.1e-71 239.0 0.0 4.7e-71 238.4 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Peptidase_S28 PF05577.12 KFP06048.1 - 2e-99 333.3 0.0 2.4e-99 333.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.7 KFP06048.1 - 9.3e-05 23.1 0.4 0.00045 20.9 0.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFP06048.1 - 0.00065 19.0 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFP06048.1 - 0.0015 18.1 0.0 0.003 17.0 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S37 PF05576.11 KFP06048.1 - 0.002 16.9 0.0 0.0036 16.0 0.0 1.4 1 0 0 1 1 1 1 PS-10 peptidase S37 DUF2920 PF11144.8 KFP06048.1 - 0.0045 16.2 0.0 0.0071 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Abhydrolase_1 PF00561.20 KFP06048.1 - 0.006 16.2 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Rep_fac-A_C PF08646.10 KFP06049.1 - 5e-11 42.5 0.1 9.6e-11 41.6 0.1 1.4 1 0 0 1 1 1 1 Replication factor-A C terminal domain GAIN_A PF18619.1 KFP06050.1 - 0.22 11.7 2.4 0.49 10.6 1.5 1.9 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Ras PF00071.22 KFP06051.1 - 1.7e-49 167.5 0.0 2.1e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP06051.1 - 6.9e-30 103.7 0.0 1.5e-29 102.6 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP06051.1 - 1.1e-13 51.0 0.0 1.4e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFP06051.1 - 1.9e-06 27.4 0.0 6e-06 25.8 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KFP06051.1 - 9.7e-06 25.6 0.1 0.053 13.4 0.2 2.3 2 1 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 KFP06051.1 - 0.00022 21.1 0.1 0.21 11.4 0.1 2.2 2 1 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA PF00004.29 KFP06051.1 - 0.00033 21.1 0.0 0.002 18.6 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.27 KFP06051.1 - 0.00068 19.2 0.0 0.014 14.9 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFP06051.1 - 0.0012 18.9 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_5 PF07728.14 KFP06051.1 - 0.0016 18.4 0.0 0.0032 17.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KFP06051.1 - 0.0026 17.5 0.0 0.0034 17.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 KFP06051.1 - 0.0038 17.0 0.1 0.045 13.5 0.1 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 KFP06051.1 - 0.0075 16.3 0.1 0.16 11.9 0.0 2.4 2 1 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE FeoB_N PF02421.18 KFP06051.1 - 0.0084 15.7 0.2 2.6 7.6 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA_22 PF13401.6 KFP06051.1 - 0.012 15.9 0.1 0.026 14.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFP06051.1 - 0.015 15.7 0.1 0.029 14.8 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain dNK PF01712.19 KFP06051.1 - 0.021 14.7 0.0 0.059 13.2 0.0 1.8 1 1 1 2 2 2 0 Deoxynucleoside kinase SRPRB PF09439.10 KFP06051.1 - 0.021 14.2 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.12 KFP06051.1 - 0.026 14.5 0.0 0.068 13.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 KFP06051.1 - 0.053 13.1 0.0 11 5.6 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TIR_2 PF13676.6 KFP06051.1 - 0.099 13.2 0.1 0.14 12.8 0.1 1.2 1 0 0 1 1 1 0 TIR domain AAA_28 PF13521.6 KFP06051.1 - 0.13 12.5 0.0 1.2 9.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain CTD_bind PF04818.13 KFP06052.1 - 1.4e-06 29.0 0.0 4.4e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. SHOCT PF09851.9 KFP06052.1 - 0.0027 17.4 0.9 0.013 15.2 0.2 2.4 2 0 0 2 2 2 1 Short C-terminal domain CFIA_Pcf11 PF11526.8 KFP06052.1 - 0.0038 17.7 0.1 0.0038 17.7 0.1 6.6 4 2 0 4 4 4 1 Subunit of cleavage factor IA Pcf11 DNA_pol3_a_NI PF14480.6 KFP06052.1 - 0.081 12.9 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus I Ank_2 PF12796.7 KFP06053.1 - 6.4e-46 154.8 21.2 2.2e-11 44.2 0.4 4.7 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP06053.1 - 3.8e-40 135.8 13.8 2.5e-10 40.7 0.1 7.2 3 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP06053.1 - 7.8e-27 93.0 11.7 1.8e-08 34.5 0.0 6.4 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 KFP06053.1 - 2.5e-25 87.7 12.2 5.6e-06 26.6 0.0 8.0 9 0 0 9 9 9 6 Ankyrin repeat Ank_3 PF13606.6 KFP06053.1 - 1.4e-23 80.4 8.4 0.0019 18.5 0.0 8.5 9 0 0 9 9 9 6 Ankyrin repeat Vps51 PF08700.11 KFP06053.1 - 0.1 12.7 3.2 0.29 11.3 3.2 1.8 1 0 0 1 1 1 0 Vps51/Vps67 Ribosomal_S11 PF00411.19 KFP06053.1 - 0.17 12.3 0.0 2.8 8.4 0.0 2.7 2 1 1 3 3 3 0 Ribosomal protein S11 DUF1640 PF07798.11 KFP06054.1 - 4.6e-60 202.6 15.8 7.2e-60 202.0 15.8 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) Vac_Fusion PF02346.16 KFP06054.1 - 0.067 12.8 3.7 0.17 11.6 0.1 3.1 2 2 1 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 HALZ PF02183.18 KFP06054.1 - 0.28 11.4 2.6 0.3 11.4 1.0 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF2408 PF10303.9 KFP06054.1 - 0.47 11.0 8.1 1.7 9.2 7.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) IZUMO PF15005.6 KFP06054.1 - 1 9.8 7.1 1.8 9.1 6.4 1.7 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated YabA PF06156.13 KFP06054.1 - 3.5 8.3 11.5 0.85 10.3 4.2 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Guanylate_kin PF00625.21 KFP06055.1 - 5.1e-66 221.8 0.1 8e-66 221.2 0.1 1.3 1 0 0 1 1 1 1 Guanylate kinase SH3_1 PF00018.28 KFP06055.1 - 4.5e-09 35.8 0.2 1.1e-08 34.5 0.2 1.7 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP06055.1 - 5e-09 35.7 0.0 1.1e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFP06055.1 - 0.0016 18.3 0.0 0.0045 16.8 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain PDZ PF00595.24 KFP06055.1 - 0.02 15.2 0.0 0.041 14.2 0.0 1.6 1 0 0 1 1 1 0 PDZ domain RHD_DNA_bind PF00554.22 KFP06056.1 - 1.5e-76 256.0 0.0 2.5e-76 255.3 0.0 1.4 1 0 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.5 KFP06056.1 - 3e-37 126.8 0.0 5.1e-37 126.0 0.0 1.4 1 0 0 1 1 1 1 Rel homology dimerisation domain Hamartin PF04388.12 KFP06056.1 - 0.3 9.7 2.5 0.43 9.2 2.5 1.1 1 0 0 1 1 1 0 Hamartin protein TPD PF14811.6 KFP06057.1 - 0.087 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif TFIID_20kDa PF03847.13 KFP06057.1 - 0.33 11.5 3.4 83 3.8 0.0 4.0 4 0 0 4 4 4 0 Transcription initiation factor TFIID subunit A Peroxin-13_N PF04088.13 KFP06058.1 - 3e-44 150.8 1.0 4.8e-44 150.2 1.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_9 PF14604.6 KFP06058.1 - 2e-10 40.3 0.0 4.9e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP06058.1 - 1e-06 28.2 0.0 1.9e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP06058.1 - 1.1e-05 25.0 0.0 2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Pex2_Pex12 PF04757.14 KFP06058.1 - 0.046 13.3 0.3 4.4 6.8 0.0 2.5 1 1 1 2 2 2 0 Pex2 / Pex12 amino terminal region SUZ PF12752.7 KFP06058.1 - 0.4 11.5 2.0 1.6 9.6 0.3 2.3 2 0 0 2 2 2 0 SUZ domain DUF3342 PF11822.8 KFP06059.1 - 2.1e-37 127.2 1.6 4.3e-37 126.2 1.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) CHORD PF04968.12 KFP06059.1 - 3.5 8.4 11.4 0.054 14.2 2.4 2.8 3 1 0 3 3 3 0 CHORD Cadherin PF00028.17 KFP06060.1 - 1.8e-25 89.2 1.2 2.7e-16 59.8 0.2 2.6 2 1 0 2 2 2 2 Cadherin domain RET_CLD1 PF17756.1 KFP06060.1 - 0.0014 18.9 0.0 1.2 9.4 0.0 2.2 2 0 0 2 2 2 2 RET Cadherin like domain 1 Cadherin PF00028.17 KFP06062.1 - 6.4e-07 29.7 0.5 2.1e-06 28.1 0.1 2.0 2 0 0 2 2 2 1 Cadherin domain DUF3213 PF11491.8 KFP06062.1 - 0.08 13.1 1.4 8.7 6.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3213) AHSA1 PF08327.11 KFP06063.1 - 1.1e-16 61.1 0.0 2.3e-16 60.2 0.0 1.5 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Aha1_N PF09229.11 KFP06063.1 - 6e-13 49.2 1.6 1.3e-12 48.1 0.5 2.0 2 1 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal SPATA1_C PF15743.5 KFP06063.1 - 0.043 13.9 1.8 2 8.5 0.0 2.2 2 0 0 2 2 2 0 Spermatogenesis-associated C-terminus Taeniidae_ag PF05596.11 KFP06063.1 - 0.11 12.5 0.9 0.21 11.6 0.1 1.9 2 0 0 2 2 2 0 Taeniidae antigen CRM1_C PF08767.11 KFP06064.1 - 2e-135 451.1 1.6 2e-135 451.1 1.6 3.0 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 KFP06064.1 - 6.5e-38 130.1 3.5 6.5e-38 130.1 3.5 5.2 6 1 0 6 6 6 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KFP06064.1 - 7.6e-36 121.6 2.0 2.8e-35 119.8 2.0 2.1 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KFP06064.1 - 2e-30 104.6 0.7 2e-30 104.6 0.7 2.6 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KFP06064.1 - 2.2e-18 65.5 3.2 4.6e-18 64.4 3.2 1.6 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KFP06064.1 - 1.9e-12 46.9 0.7 9.2e-12 44.7 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Hydrolase_3 PF08282.12 KFP06064.1 - 0.064 13.0 2.5 0.12 12.1 0.0 2.6 3 1 1 4 4 4 0 haloacid dehalogenase-like hydrolase Vac14_Fab1_bd PF12755.7 KFP06064.1 - 0.55 10.9 2.7 4.3 8.0 0.1 3.8 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region UPF0564 PF10595.9 KFP06065.1 - 5.8e-60 203.3 37.1 1.2e-59 202.3 37.1 1.5 1 0 0 1 1 1 1 Uncharacterised protein family UPF0564 MethyltransfD12 PF02086.15 KFP06065.1 - 0.04 13.6 2.2 0.072 12.8 0.1 2.3 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase Cpn60_TCP1 PF00118.24 KFP06066.1 - 3.2e-157 524.1 16.0 3.6e-157 523.9 16.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.12 KFP06066.1 - 0.061 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Phage Tail Protein X LRR_8 PF13855.6 KFP06067.1 - 1.5e-23 82.3 23.1 1.2e-09 37.7 2.1 5.1 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KFP06067.1 - 2.7e-17 62.6 19.6 0.00023 21.5 0.5 6.5 3 2 3 6 6 6 6 Leucine Rich repeats (2 copies) fn3 PF00041.21 KFP06067.1 - 6.3e-11 42.5 0.1 1.7e-10 41.1 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III domain LRR_9 PF14580.6 KFP06067.1 - 0.00055 19.5 1.0 0.041 13.4 0.2 2.3 2 0 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFP06067.1 - 3.2 8.6 25.8 25 6.0 0.0 8.7 8 2 0 8 8 8 0 Leucine Rich Repeat FERM_M PF00373.18 KFP06068.1 - 1.6e-42 144.6 0.0 3.8e-42 143.4 0.0 1.7 1 1 0 1 1 1 1 FERM central domain Kindlin_2_N PF18124.1 KFP06068.1 - 6.7e-35 119.2 5.1 1.7e-34 117.8 5.1 1.8 1 0 0 1 1 1 1 Kindlin-2 N-terminal domain PH PF00169.29 KFP06068.1 - 1.1e-11 45.2 0.0 1.8e-10 41.2 0.0 2.8 3 0 0 3 3 3 1 PH domain FERM_N PF09379.10 KFP06068.1 - 0.0043 17.0 0.0 0.02 14.8 0.0 2.2 1 1 0 1 1 1 1 FERM N-terminal domain PH_17 PF18012.1 KFP06068.1 - 0.051 13.3 0.0 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 PH domain PH_8 PF15409.6 KFP06068.1 - 0.064 13.6 0.0 0.064 13.6 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain TGFb_propeptide PF00688.18 KFP06069.1 - 6.7e-37 127.6 0.5 1.1e-36 126.9 0.5 1.3 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 KFP06069.1 - 1e-34 119.6 0.6 1.9e-34 118.7 0.6 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain FMN_dh PF01070.18 KFP06070.1 - 5.5e-136 453.2 0.0 6.2e-136 453.0 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KFP06070.1 - 7.1e-07 28.5 1.5 1.9e-06 27.1 0.6 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KFP06070.1 - 2.2e-05 23.9 0.5 0.18 11.1 0.0 2.7 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 KFP06070.1 - 2.3e-05 23.7 0.1 3.8e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KFP06070.1 - 0.00057 19.4 0.4 0.0066 15.9 0.1 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein NMO PF03060.15 KFP06070.1 - 0.0026 17.2 1.1 0.0057 16.1 1.2 1.5 1 1 0 1 1 1 1 Nitronate monooxygenase Dus PF01207.17 KFP06070.1 - 0.0032 16.6 0.1 1.6 7.8 0.1 2.3 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) CdhD PF03599.16 KFP06070.1 - 0.0067 15.2 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit DHO_dh PF01180.21 KFP06070.1 - 0.0095 15.2 0.2 0.029 13.6 0.0 1.8 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 KFP06070.1 - 0.045 13.2 0.1 4.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator TMP-TENI PF02581.17 KFP06070.1 - 0.079 12.3 0.4 0.34 10.2 0.0 2.2 3 0 0 3 3 3 0 Thiamine monophosphate synthase MFS_MOT1 PF16983.5 KFP06070.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Molybdate transporter of MFS superfamily Thioredoxin PF00085.20 KFP06071.1 - 6.8e-19 67.8 0.0 8.5e-19 67.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 KFP06071.1 - 0.0067 16.3 0.0 0.0089 15.9 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 KFP06071.1 - 0.018 14.4 0.0 0.022 14.1 0.0 1.4 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KFP06071.1 - 0.039 14.4 0.1 0.11 12.9 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KFP06071.1 - 0.13 12.1 0.1 0.18 11.5 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin AhpC-TSA PF00578.21 KFP06071.1 - 0.13 12.2 0.1 0.18 11.7 0.0 1.3 1 1 0 1 1 1 0 AhpC/TSA family DUF953 PF06110.11 KFP06071.1 - 0.13 11.8 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) PI-PLC-X PF00388.19 KFP06072.1 - 1.8e-58 196.2 0.2 7.4e-58 194.3 0.0 2.3 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PLC-beta_C PF08703.10 KFP06072.1 - 4.7e-47 160.2 46.6 4.7e-47 160.2 46.6 3.0 3 0 0 3 3 3 1 PLC-beta C terminal PI-PLC-Y PF00387.19 KFP06072.1 - 5.9e-40 136.2 1.5 5.9e-40 136.2 1.5 4.0 2 1 2 4 4 4 1 Phosphatidylinositol-specific phospholipase C, Y domain PH_14 PF17787.1 KFP06072.1 - 9.5e-19 67.6 0.0 2.5e-18 66.2 0.0 1.8 1 0 0 1 1 1 1 PH domain EF-hand_like PF09279.11 KFP06072.1 - 5.6e-11 42.8 0.0 5.6e-11 42.8 0.0 3.2 2 1 2 4 4 4 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 KFP06072.1 - 3.8e-07 30.3 0.1 1.4e-06 28.5 0.0 2.1 2 0 0 2 2 2 1 C2 domain DUF1154 PF06631.11 KFP06072.1 - 1e-06 28.7 10.8 1e-06 28.7 10.8 3.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1154) DUF760 PF05542.11 KFP06072.1 - 0.058 13.8 0.4 15 6.0 0.3 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF760) DUF4510 PF14971.6 KFP06072.1 - 1.7 9.0 12.7 26 5.2 9.8 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4510) Lamp PF01299.17 KFP06073.1 - 1.8e-17 63.6 0.1 2.6e-17 63.0 0.1 1.3 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) ATP-synt_S1 PF05827.12 KFP06073.1 - 2.2e-07 30.8 0.9 5.1e-07 29.6 0.9 1.7 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Chordopox_A13L PF05961.11 KFP06073.1 - 0.048 13.9 0.1 0.096 12.9 0.1 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF5305 PF17231.2 KFP06073.1 - 0.064 12.6 0.0 0.12 11.7 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Pkinase PF00069.25 KFP06074.1 - 1.4e-68 231.1 0.0 1.8e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP06074.1 - 5e-45 153.8 0.0 7.1e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KFP06074.1 - 1.9e-15 57.0 0.1 4.3e-15 55.8 0.1 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KFP06074.1 - 4e-08 32.9 0.0 8.5e-08 31.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP06074.1 - 8.9e-05 21.4 0.0 0.00015 20.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP06074.1 - 0.13 12.2 0.2 3.4 7.5 0.0 2.8 1 1 2 3 3 3 0 Phosphotransferase enzyme family adh_short PF00106.25 KFP06075.1 - 6.8e-22 77.9 0.0 1.2e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP06075.1 - 1.7e-13 50.7 0.0 2.1e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KFP06075.1 - 1.4e-05 24.6 0.0 1.6e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) HMG_box PF00505.19 KFP06075.1 - 0.0015 18.9 2.1 0.0024 18.3 0.4 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box Ank_2 PF12796.7 KFP06076.1 - 5e-54 180.8 2.8 1.7e-11 44.6 0.2 5.8 4 1 2 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP06076.1 - 5e-45 146.3 7.1 1e-06 28.6 0.0 10.2 10 0 0 10 10 10 7 Ankyrin repeat Ank_4 PF13637.6 KFP06076.1 - 1.4e-44 149.9 9.7 8.8e-15 54.9 0.1 8.1 5 2 4 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 KFP06076.1 - 8.9e-42 139.8 7.0 1e-06 28.9 0.0 9.5 9 1 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 KFP06076.1 - 2.5e-41 139.2 7.7 1.1e-07 31.9 0.0 8.5 4 3 6 10 10 10 7 Ankyrin repeats (many copies) UDPG_MGDP_dh_C PF03720.15 KFP06076.1 - 0.13 12.7 0.0 77 3.8 0.0 3.8 3 1 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain SNAP-25 PF00835.19 KFP06077.1 - 1.3e-21 76.6 0.2 2.7e-21 75.6 0.2 1.6 1 0 0 1 1 1 1 SNAP-25 family DUF5089 PF17002.5 KFP06077.1 - 6.4e-05 22.9 0.1 8.6e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5089) V-SNARE_C PF12352.8 KFP06077.1 - 0.069 13.4 3.1 0.37 11.1 0.1 2.7 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus DUF349 PF03993.12 KFP06077.1 - 0.12 12.6 1.1 0.43 10.9 0.1 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Rx_N PF18052.1 KFP06077.1 - 0.16 12.3 1.8 0.49 10.7 0.1 2.0 2 0 0 2 2 2 0 Rx N-terminal domain FlaC_arch PF05377.11 KFP06077.1 - 8.4 6.9 7.5 19 5.8 1.1 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Cpn60_TCP1 PF00118.24 KFP06078.1 - 1.2e-99 334.2 0.0 1.3e-99 334.0 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EGF PF00008.27 KFP06079.1 - 2e-79 261.4 285.4 2e-09 37.6 7.7 19.4 19 1 0 19 19 19 14 EGF-like domain hEGF PF12661.7 KFP06079.1 - 5.4e-53 175.9 252.6 4.8e-07 30.2 7.3 20.8 22 0 0 22 22 22 14 Human growth factor-like EGF MNNL PF07657.13 KFP06079.1 - 6e-28 96.7 3.4 6e-28 96.7 3.4 6.8 7 1 0 7 7 7 1 N terminus of Notch ligand EGF_2 PF07974.13 KFP06079.1 - 5.7e-26 90.6 330.4 0.00029 21.1 11.1 19.7 20 0 0 20 20 20 13 EGF-like domain DSL PF01414.19 KFP06079.1 - 4.9e-24 84.4 7.9 4.9e-24 84.4 7.9 15.7 13 2 4 17 17 17 2 Delta serrate ligand EGF_CA PF07645.15 KFP06079.1 - 8e-07 29.2 25.0 5.4e-05 23.3 8.7 19.3 10 5 9 20 20 20 11 Calcium-binding EGF domain DUF2920 PF11144.8 KFP06079.1 - 0.0057 15.9 0.7 0.0097 15.1 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) cEGF PF12662.7 KFP06079.1 - 0.011 15.7 3.3 0.011 15.7 3.3 17.9 16 3 0 16 16 16 0 Complement Clr-like EGF-like MAP17 PF15807.5 KFP06079.1 - 0.15 12.3 0.9 0.29 11.4 0.9 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 CLN3 PF02487.17 KFP06079.1 - 0.22 10.5 0.2 0.33 9.9 0.2 1.1 1 0 0 1 1 1 0 CLN3 protein PHR PF08005.12 KFP06080.1 - 1.4e-43 149.2 0.9 1.4e-43 149.2 0.9 1.7 2 0 0 2 2 2 1 PHR domain BTB PF00651.31 KFP06080.1 - 5.1e-24 84.6 0.0 3.2e-23 82.1 0.0 2.2 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFP06080.1 - 9.4e-08 32.1 3.5 1.1e-07 31.8 1.4 2.2 2 1 0 2 2 2 1 BTB And C-terminal Kelch RVT_1 PF00078.27 KFP06081.1 - 0.072 12.6 0.0 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) CFTR_R PF14396.6 KFP06082.1 - 1.8e-102 341.4 1.2 1.8e-102 341.4 1.2 1.9 2 0 0 2 2 2 1 Cystic fibrosis TM conductance regulator (CFTR), regulator domain ABC_membrane PF00664.23 KFP06082.1 - 4.1e-94 315.3 40.4 6.8e-51 173.5 18.2 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFP06082.1 - 6.9e-35 120.5 0.0 7.4e-22 78.3 0.0 3.6 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFP06082.1 - 5e-06 26.1 0.0 0.0035 16.8 0.0 2.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFP06082.1 - 0.0008 19.3 0.1 0.18 11.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFP06082.1 - 0.02 14.8 0.0 0.052 13.4 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase T2SSE PF00437.20 KFP06082.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 KFP06082.1 - 0.32 11.5 7.0 0.75 10.3 0.1 3.0 3 0 0 3 3 3 0 AAA domain Ank_2 PF12796.7 KFP06083.1 - 4.9e-28 97.5 1.0 5.4e-18 65.4 0.1 3.9 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFP06083.1 - 2e-27 94.4 0.2 1.8e-07 31.3 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KFP06083.1 - 5.8e-23 80.7 3.0 1.4e-11 44.4 0.0 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP06083.1 - 8.1e-22 75.0 1.3 0.0001 22.4 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KFP06083.1 - 2.1e-19 69.6 0.6 1.6e-07 31.7 0.0 4.0 1 1 2 4 4 4 3 Ankyrin repeats (many copies) SAM_1 PF00536.30 KFP06083.1 - 8.7e-10 38.9 0.2 1.7e-09 38.0 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP06083.1 - 8.1e-08 32.3 0.2 2.1e-07 31.0 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) wnt PF00110.19 KFP06084.1 - 5.5e-121 403.9 27.3 6.2e-121 403.7 27.3 1.0 1 0 0 1 1 1 1 wnt family ST7 PF04184.12 KFP06085.1 - 9.4e-274 908.8 5.1 1.4e-273 908.3 5.1 1.3 1 1 0 1 1 1 1 ST7 protein TPR_6 PF13174.6 KFP06085.1 - 0.00038 20.9 0.0 0.0021 18.6 0.0 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Clathrin PF00637.20 KFP06085.1 - 0.048 13.5 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Region in Clathrin and VPS TPR_19 PF14559.6 KFP06085.1 - 0.11 13.0 4.7 0.3 11.6 0.2 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFP06085.1 - 0.13 12.4 5.6 3.4 8.0 0.0 4.5 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFP06085.1 - 0.14 12.0 2.8 23 5.0 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat F-actin_cap_A PF01267.17 KFP06086.1 - 5.2e-107 357.2 2.4 5.9e-107 357.0 2.4 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit DUF5121 PF17165.4 KFP06086.1 - 0.053 13.9 0.3 0.15 12.5 0.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5121) CCP_MauG PF03150.14 KFP06086.1 - 0.068 13.8 0.9 0.26 11.9 0.5 2.1 1 1 1 2 2 2 0 Di-haem cytochrome c peroxidase Pkinase_Tyr PF07714.17 KFP06087.1 - 1.5e-93 312.8 0.0 2.2e-93 312.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Sema PF01403.19 KFP06087.1 - 1.3e-51 175.8 4.2 2e-51 175.1 4.2 1.2 1 0 0 1 1 1 1 Sema domain Pkinase PF00069.25 KFP06087.1 - 3.8e-39 134.6 0.0 7.7e-39 133.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain TIG PF01833.24 KFP06087.1 - 4.9e-35 119.5 7.9 5.5e-15 55.2 0.1 4.9 4 0 0 4 4 4 4 IPT/TIG domain Kinase-like PF14531.6 KFP06087.1 - 8e-05 22.1 0.1 0.00029 20.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like PSI PF01437.25 KFP06087.1 - 0.0002 21.9 16.3 0.0002 21.9 16.3 2.4 2 0 0 2 2 2 1 Plexin repeat Pkinase_fungal PF17667.1 KFP06087.1 - 0.0053 15.6 0.0 0.0082 15.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Caveolin PF01146.17 KFP06088.1 - 2.5e-51 173.1 4.1 2.8e-51 173.0 4.1 1.0 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.17 KFP06089.1 - 1.6e-48 164.1 6.2 1.7e-48 163.9 6.2 1.0 1 0 0 1 1 1 1 Caveolin VraX PF17412.2 KFP06089.1 - 0.02 14.5 0.2 8.5 6.1 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function Flu_C_NS2 PF03555.14 KFP06090.1 - 0.084 13.1 1.3 0.12 12.6 1.3 1.4 1 1 0 1 1 1 0 Influenza C non-structural protein (NS2) Pkinase_Tyr PF07714.17 KFP06092.1 - 7e-48 163.2 0.0 1.3e-47 162.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP06092.1 - 5.6e-39 134.1 0.0 8.7e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SAM_KSR1 PF13543.6 KFP06092.1 - 5.2e-17 62.2 0.1 9.7e-17 61.3 0.1 1.5 1 0 0 1 1 1 1 SAM like domain present in kinase suppressor RAS 1 Kinase-like PF14531.6 KFP06092.1 - 9.2e-05 21.9 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like C1_1 PF00130.22 KFP06092.1 - 0.00061 19.6 12.2 0.0012 18.7 12.2 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RIO1 PF01163.22 KFP06092.1 - 0.003 17.2 0.0 0.0056 16.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KFP06092.1 - 0.082 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KFP06092.1 - 0.14 11.5 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING-like PF08746.11 KFP06092.1 - 0.16 12.3 11.3 0.41 11.0 11.3 1.7 1 0 0 1 1 1 0 RING-like domain FTA2 PF13095.6 KFP06092.1 - 0.17 11.4 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 FAM76 PF16046.5 KFP06092.1 - 0.89 8.8 8.4 1.6 8.0 8.4 1.3 1 0 0 1 1 1 0 FAM76 protein C1_2 PF03107.16 KFP06092.1 - 1.4 9.3 7.0 3.8 7.9 7.0 1.7 1 0 0 1 1 1 0 C1 domain NO_synthase PF02898.15 KFP06093.1 - 3.2e-186 618.6 0.0 4.4e-186 618.2 0.0 1.2 1 0 0 1 1 1 1 Nitric oxide synthase, oxygenase domain FAD_binding_1 PF00667.20 KFP06093.1 - 1.3e-71 240.7 0.0 2.7e-71 239.7 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFP06093.1 - 8.4e-41 139.5 0.0 1.7e-40 138.5 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KFP06093.1 - 8.2e-22 77.9 0.3 2.6e-21 76.3 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Complex1_LYR PF05347.15 KFP06094.1 - 1.8e-16 60.0 0.6 1.9e-16 59.8 0.6 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFP06094.1 - 0.00028 21.6 0.5 0.00032 21.4 0.5 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KFP06094.1 - 0.0013 19.3 0.0 0.0013 19.2 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DUF1320 PF07030.12 KFP06094.1 - 0.037 14.1 2.4 0.97 9.6 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1320) ETC_C1_NDUFA5 PF04716.14 KFP06094.1 - 0.04 13.7 0.1 0.049 13.4 0.1 1.2 1 0 0 1 1 1 0 ETC complex I subunit conserved region DinI PF06183.13 KFP06094.1 - 0.066 13.6 0.1 0.082 13.3 0.1 1.2 1 0 0 1 1 1 0 DinI-like family Sigma70_r4 PF04545.16 KFP06094.1 - 0.071 12.6 1.2 9.5 5.8 0.1 2.3 2 1 0 2 2 2 0 Sigma-70, region 4 Pkinase PF00069.25 KFP06095.1 - 4.9e-64 216.2 0.0 8.2e-64 215.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP06095.1 - 4.7e-31 108.0 0.0 7.4e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFP06095.1 - 6.6e-05 22.0 0.1 0.00014 20.9 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KFP06095.1 - 0.00015 20.7 0.0 0.00023 20.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFP06095.1 - 0.013 14.9 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KFP06095.1 - 0.033 14.1 4.9 0.15 11.9 4.9 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KFP06095.1 - 0.039 13.6 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF2781 PF10914.8 KFP06096.1 - 1.4e-19 70.9 1.3 1.5e-19 70.9 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) IFT20 PF14931.6 KFP06097.1 - 1.4e-32 112.3 8.7 1.6e-32 112.2 8.7 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 HRDC PF00570.23 KFP06097.1 - 0.015 15.3 0.8 0.019 14.9 0.8 1.2 1 0 0 1 1 1 0 HRDC domain Nnf1 PF03980.14 KFP06097.1 - 0.019 15.4 3.4 0.023 15.1 3.4 1.1 1 0 0 1 1 1 0 Nnf1 DUF3467 PF11950.8 KFP06097.1 - 0.064 13.5 0.2 0.095 12.9 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3467) DUF737 PF05300.11 KFP06097.1 - 0.43 10.9 6.3 0.48 10.8 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) BTB_2 PF02214.22 KFP06098.1 - 2.6e-20 72.6 0.0 4.9e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KFP06098.1 - 4.9e-06 26.8 0.0 1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KFP06098.1 - 0.015 15.4 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain PH_RBD PF12068.8 KFP06099.1 - 1.1e-35 122.6 0.2 5.2e-33 113.9 0.0 3.2 2 1 0 2 2 2 2 Rab-binding domain (RBD) RUN PF02759.19 KFP06099.1 - 5.5e-32 110.5 0.0 1.7e-31 109.0 0.0 1.9 1 0 0 1 1 1 1 RUN domain RabGAP-TBC PF00566.18 KFP06099.1 - 1.4e-31 109.9 10.2 1e-29 103.8 6.4 2.6 2 0 0 2 2 2 2 Rab-GTPase-TBC domain zf-BED PF02892.15 KFP06099.1 - 0.0076 16.3 1.6 0.011 15.7 0.1 2.1 2 0 0 2 2 2 1 BED zinc finger HLH PF00010.26 KFP06100.1 - 5.4e-13 48.7 2.2 5.4e-13 48.7 2.2 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain APG6_N PF17675.1 KFP06100.1 - 0.061 13.9 7.2 0.1 13.1 7.2 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Sipho_Gp157 PF05565.11 KFP06100.1 - 0.062 13.3 5.9 0.11 12.5 5.9 1.4 1 1 0 1 1 1 0 Siphovirus Gp157 DUF773 PF05600.12 KFP06100.1 - 0.34 9.6 8.8 0.024 13.4 4.0 1.4 2 0 0 2 2 2 0 CDK5 regulatory subunit-associated protein 3 Fmp27_WPPW PF10359.9 KFP06100.1 - 0.44 9.3 6.6 0.62 8.8 6.6 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain LMBR1 PF04791.16 KFP06100.1 - 0.93 8.3 3.1 1.3 7.9 3.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein WD40 PF00400.32 KFP06101.1 - 8.3e-63 206.8 17.9 1.3e-08 35.3 0.6 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP06101.1 - 2.9e-16 59.5 2.7 0.047 14.0 0.0 5.8 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP06101.1 - 1.5e-12 47.0 11.3 0.01 14.5 0.0 6.4 2 2 4 7 7 7 4 Nucleoporin Nup120/160 LisH PF08513.11 KFP06101.1 - 6.5e-09 35.4 0.4 1.6e-08 34.2 0.4 1.7 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 KFP06101.1 - 3.3e-05 23.9 2.6 0.097 12.5 0.1 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 KFP06101.1 - 4.8e-05 22.3 1.4 0.21 10.3 0.0 4.0 1 1 4 5 5 5 1 Nup133 N terminal like Ge1_WD40 PF16529.5 KFP06101.1 - 0.00035 19.6 8.7 1.3 7.9 0.2 5.1 1 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Pox_A_type_inc PF04508.12 KFP06101.1 - 0.0016 18.2 0.1 0.0037 17.0 0.1 1.6 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat LisH_2 PF16045.5 KFP06101.1 - 0.018 14.1 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 LisH Roc PF08477.13 KFP06101.1 - 0.055 13.7 0.8 1.7 8.9 0.0 3.0 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CLU PF13236.6 KFP06102.1 - 8.2e-88 293.9 0.0 1.4e-87 293.2 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 KFP06102.1 - 4.9e-60 202.6 0.0 1.1e-59 201.4 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 KFP06102.1 - 4.4e-23 81.4 7.3 3.8e-10 39.9 0.3 3.8 1 1 1 3 3 3 3 Tetratricopeptide repeat CLU_N PF15044.6 KFP06102.1 - 6.5e-13 48.8 0.8 2.3e-12 47.1 0.0 2.4 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 KFP06102.1 - 5.9e-08 32.3 5.9 9.5e-05 22.1 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP06102.1 - 2.1e-06 27.4 3.3 6.5e-06 25.7 0.2 2.3 2 0 0 2 2 2 1 MalT-like TPR region DUF727 PF05303.12 KFP06102.1 - 0.00026 21.0 0.0 0.00088 19.3 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_2 PF07719.17 KFP06102.1 - 0.96 9.7 4.0 3.3 8.0 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP06102.1 - 3.4 7.9 6.0 4.3 7.6 0.2 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF1151 PF06625.11 KFP06102.1 - 5.3 7.0 8.3 0.2 11.6 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) CCDC92 PF14916.6 KFP06103.1 - 1.7e-18 66.1 12.0 1.7e-18 66.1 12.0 2.1 2 1 0 2 2 2 1 Coiled-coil domain of unknown function Calici_MSP PF05752.11 KFP06103.1 - 0.0048 16.7 2.6 0.012 15.4 2.6 1.6 1 1 0 1 1 1 1 Calicivirus minor structural protein Lipoprotein_6 PF01441.19 KFP06103.1 - 0.034 14.2 2.2 0.041 13.9 2.2 1.1 1 0 0 1 1 1 0 Lipoprotein Rootletin PF15035.6 KFP06103.1 - 0.048 13.7 15.6 7.6 6.5 15.6 2.2 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Atg14 PF10186.9 KFP06103.1 - 0.051 12.6 14.9 0.064 12.3 14.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Nbl1_Borealin_N PF10444.9 KFP06103.1 - 0.054 13.1 1.4 0.054 13.1 1.4 3.0 2 1 0 3 3 3 0 Nbl1 / Borealin N terminal Cob_adeno_trans PF01923.18 KFP06103.1 - 0.11 12.7 6.6 0.14 12.3 6.6 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase FlxA PF14282.6 KFP06103.1 - 0.17 11.9 12.5 1.2 9.2 4.2 2.1 1 1 1 2 2 2 0 FlxA-like protein GAS PF13851.6 KFP06103.1 - 0.3 10.4 19.8 0.55 9.5 7.2 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding EIAV_Rev PF11129.8 KFP06103.1 - 0.4 10.9 5.1 0.56 10.4 2.4 1.9 1 1 1 2 2 2 0 Rev protein of equine infectious anaemia virus ATG16 PF08614.11 KFP06103.1 - 0.42 10.8 17.6 0.66 10.2 17.2 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) HIP1_clath_bdg PF16515.5 KFP06103.1 - 0.44 11.2 18.8 0.56 10.8 10.2 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TPD52 PF04201.15 KFP06103.1 - 1 9.0 16.6 0.17 11.5 7.3 2.2 1 1 1 2 2 2 0 Tumour protein D52 family DivIC PF04977.15 KFP06103.1 - 2.6 7.9 16.6 1.9 8.3 0.3 3.1 1 1 2 3 3 3 0 Septum formation initiator FlaC_arch PF05377.11 KFP06103.1 - 2.6 8.5 7.3 17 5.9 1.0 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Tox-ODYAM1 PF15642.6 KFP06103.1 - 3.3 6.6 9.0 3.7 6.4 9.0 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus CENP-H PF05837.12 KFP06103.1 - 5.4 7.5 15.1 43 4.6 14.0 2.4 1 1 0 1 1 1 0 Centromere protein H (CENP-H) DUF4407 PF14362.6 KFP06103.1 - 6.3 6.1 7.6 4.4 6.6 5.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ACCA PF03255.14 KFP06103.1 - 6.4 6.6 11.0 1.3 8.9 3.0 2.0 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Rap_GAP PF02145.15 KFP06104.1 - 7.1e-59 198.5 0.0 1.1e-58 197.9 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP WSC PF01822.19 KFP06105.1 - 2.6e-31 107.6 17.6 7.3e-20 71.0 10.1 2.3 2 0 0 2 2 2 2 WSC domain Sulfotransfer_1 PF00685.27 KFP06105.1 - 3.9e-08 33.1 0.2 7.3e-08 32.2 0.2 1.4 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP06105.1 - 0.026 14.9 0.0 0.053 13.9 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase family DUF2859 PF11072.8 KFP06105.1 - 0.04 13.7 0.1 0.081 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) PAN_1 PF00024.26 KFP06105.1 - 1.8 8.6 7.1 15 5.6 0.1 3.2 3 0 0 3 3 3 0 PAN domain XAF1_C PF18608.1 KFP06106.1 - 3.7e-15 55.2 0.5 3.7e-15 55.2 0.5 2.5 3 0 0 3 3 3 1 XIAP-associated factor 1 C-terminal domain zf_UBZ PF18439.1 KFP06106.1 - 1.4e-06 27.8 11.1 0.074 12.7 0.1 4.3 4 0 0 4 4 4 3 Ubiquitin-Binding Zinc Finger DZR PF12773.7 KFP06106.1 - 0.0019 18.2 1.7 0.0019 18.2 1.7 3.3 3 1 0 3 3 3 1 Double zinc ribbon CarbpepA_inh PF02977.15 KFP06106.1 - 0.0096 15.7 1.8 0.0096 15.7 1.8 2.9 3 0 0 3 3 3 1 Carboxypeptidase A inhibitor zf-ACC PF17848.1 KFP06106.1 - 0.043 13.9 0.1 0.043 13.9 0.1 3.4 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain zf-C2H2 PF00096.26 KFP06106.1 - 0.14 12.7 12.1 2.6 8.7 0.8 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP06106.1 - 2.2 9.3 16.8 4.4 8.4 0.1 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger zinc-ribbons_6 PF07191.12 KFP06106.1 - 5.7 7.0 13.5 0.59 10.1 2.0 3.5 3 1 0 3 3 3 0 zinc-ribbons zf-RING_7 PF02591.15 KFP06106.1 - 5.9 7.2 0.0 5.9 7.2 0.0 3.7 4 0 0 4 4 4 0 C4-type zinc ribbon domain Zn-ribbon_8 PF09723.10 KFP06106.1 - 6.7 6.9 9.2 7 6.9 2.1 3.5 3 1 0 3 3 3 0 Zinc ribbon domain Sgf11 PF08209.11 KFP06106.1 - 9.6 5.9 14.2 0.12 12.0 1.8 3.5 4 0 0 4 4 4 0 Sgf11 (transcriptional regulation protein) Na_sulph_symp PF00939.19 KFP06107.1 - 2e-118 396.4 23.5 2.3e-118 396.2 23.5 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KFP06107.1 - 1e-34 120.1 31.2 2.4e-21 76.2 2.6 3.1 2 1 1 3 3 3 3 Citrate transporter DUF4713 PF15831.5 KFP06107.1 - 2.9 8.4 12.7 18 5.9 0.1 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4713) Med31 PF05669.12 KFP06108.1 - 1e-40 137.6 11.2 1.6e-40 137.0 11.2 1.2 1 0 0 1 1 1 1 SOH1 DUF953 PF06110.11 KFP06109.1 - 1.6e-43 147.1 0.0 1.7e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 KFP06109.1 - 0.13 12.1 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin DDHD PF02862.17 KFP06110.1 - 6.1e-51 173.7 0.0 1.8e-50 172.2 0.0 1.9 2 0 0 2 2 2 1 DDHD domain Acid_phosphat_B PF03767.14 KFP06110.1 - 0.019 14.5 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) LNS2 PF08235.13 KFP06110.1 - 0.046 13.2 0.1 0.24 10.8 0.1 2.0 1 1 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) RCS1 PF07326.11 KFP06111.1 - 2.3e-48 165.2 7.5 2.5e-48 165.0 7.5 1.0 1 0 0 1 1 1 1 Regulator of chromosome segregation 1 F-box-like PF12937.7 KFP06112.1 - 1.8e-08 34.2 1.9 1.8e-08 34.2 1.9 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFP06112.1 - 2.5e-06 27.2 0.2 2.5e-06 27.2 0.2 2.7 3 0 0 3 3 3 1 F-box domain F-box_5 PF18511.1 KFP06112.1 - 0.00018 21.0 0.6 0.00054 19.5 0.6 1.7 1 0 0 1 1 1 1 F-box Tektin PF03148.14 KFP06113.1 - 1.4e-141 471.8 33.5 1.5e-141 471.6 33.5 1.0 1 0 0 1 1 1 1 Tektin family CdiI_2 PF18593.1 KFP06113.1 - 0.11 13.2 3.6 0.53 11.0 0.0 3.5 3 1 1 4 4 4 0 CdiI immunity protein V_ATPase_I PF01496.19 KFP06113.1 - 0.66 7.8 15.5 0.43 8.4 4.7 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 KFP06113.1 - 0.79 9.2 21.9 0.37 10.3 5.3 2.7 1 1 1 2 2 2 0 Exonuclease VII, large subunit YlqD PF11068.8 KFP06113.1 - 3.3 8.1 22.5 1.4 9.3 5.6 3.6 3 0 0 3 3 3 0 YlqD protein DUF948 PF06103.11 KFP06113.1 - 4.5 7.6 16.9 6.5 7.1 0.6 4.2 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF883 PF05957.13 KFP06113.1 - 5.5 7.7 17.5 15 6.3 2.5 4.3 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) CH PF00307.31 KFP06114.1 - 5.8e-22 77.9 0.0 9e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFP06114.1 - 7.3e-05 22.5 0.1 0.00012 21.8 0.1 1.4 1 0 0 1 1 1 1 CAMSAP CH domain Ank_5 PF13857.6 KFP06115.1 - 1.2e-17 63.7 0.0 3.4e-10 40.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP06115.1 - 2.3e-17 63.1 0.1 4.3e-12 46.3 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP06115.1 - 2.5e-14 53.6 0.1 3.2e-13 50.1 0.0 2.2 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFP06115.1 - 1.1e-13 51.0 0.1 9.2e-07 29.0 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFP06115.1 - 2.9e-12 45.6 0.1 7e-07 29.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat FAM180 PF15173.6 KFP06117.1 - 2e-61 205.9 0.6 2.3e-61 205.8 0.6 1.0 1 0 0 1 1 1 1 FAM180 family RRP36 PF06102.12 KFP06117.1 - 0.092 12.7 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 Na_sulph_symp PF00939.19 KFP06118.1 - 8.3e-100 335.1 9.0 1.3e-99 334.4 9.0 1.3 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KFP06118.1 - 4.7e-35 121.2 15.7 1.2e-16 60.8 0.0 3.1 2 1 1 3 3 3 3 Citrate transporter SbmA_BacA PF05992.12 KFP06118.1 - 2.2 7.6 6.2 3.4 7.0 1.9 2.5 2 0 0 2 2 2 0 SbmA/BacA-like family Lipase_GDSL_2 PF13472.6 KFP06119.1 - 0.0025 18.2 0.0 0.0045 17.4 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 KFP06119.1 - 0.0066 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 OSK domain DUF4644 PF15486.6 KFP06119.1 - 0.022 14.6 0.1 0.04 13.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4644) Noelin-1 PF12308.8 KFP06119.1 - 0.14 12.1 0.8 0.27 11.3 0.8 1.4 1 0 0 1 1 1 0 Neurogenesis glycoprotein C2 PF00168.30 KFP06121.1 - 7.5e-54 180.4 0.0 1.3e-27 96.0 0.0 2.3 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 KFP06121.1 - 4.5e-05 23.4 0.1 0.62 10.0 0.0 3.2 3 1 0 3 3 3 2 Phosphoinositide 3-kinase C2 CEP76-C2 PF15627.6 KFP06121.1 - 0.0032 17.0 0.0 1.3 8.6 0.0 2.6 3 0 0 3 3 3 2 CEP76 C2 domain MOZART1 PF12554.8 KFP06122.1 - 9e-24 83.0 0.4 1e-23 82.8 0.4 1.0 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Rad50_zn_hook PF04423.14 KFP06122.1 - 0.041 13.7 0.0 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 Rad50 zinc hook motif CBP_BcsN PF17038.5 KFP06122.1 - 0.09 12.1 0.1 0.094 12.1 0.1 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsN BORA_N PF15280.6 KFP06123.1 - 6.2e-67 225.6 5.7 3.7e-66 223.0 5.7 2.1 1 1 0 1 1 1 1 Protein aurora borealis N-terminus IRS PF02174.17 KFP06124.1 - 3.7e-25 87.7 0.1 1.2e-24 86.1 0.1 1.8 2 0 0 2 2 2 1 PTB domain (IRS-1 type) Cpn60_TCP1 PF00118.24 KFP06125.1 - 5.5e-148 493.6 11.7 6.4e-148 493.4 11.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2529 PF10740.9 KFP06125.1 - 0.0067 16.1 0.1 0.029 14.0 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF2529) Ribosomal_S13 PF00416.22 KFP06125.1 - 0.13 12.7 2.1 0.31 11.4 0.3 2.5 3 0 0 3 3 3 0 Ribosomal protein S13/S18 DUF5442 PF17514.2 KFP06125.1 - 0.15 12.2 0.2 0.31 11.2 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5442) Asp PF00026.23 KFP06126.1 - 5e-114 381.0 0.0 5.7e-114 380.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFP06126.1 - 4.2e-12 46.7 0.9 7.7e-10 39.3 0.9 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.12 KFP06126.1 - 5e-10 39.1 0.7 8.6e-10 38.3 0.7 1.4 1 0 0 1 1 1 1 A1 Propeptide TAXi_C PF14541.6 KFP06126.1 - 0.00039 20.2 0.0 0.00098 18.9 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Bestrophin PF01062.21 KFP06127.1 - 1.9e-100 336.1 4.3 2.6e-100 335.6 4.3 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Sec2p PF06428.11 KFP06128.1 - 2e-08 34.1 9.2 2e-08 34.1 9.2 2.1 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p FAM76 PF16046.5 KFP06128.1 - 0.002 17.5 2.9 0.0034 16.8 2.9 1.3 1 0 0 1 1 1 1 FAM76 protein T3SSipB PF16535.5 KFP06128.1 - 0.033 14.7 4.5 0.057 13.9 4.5 1.3 1 0 0 1 1 1 0 Type III cell invasion protein SipB DUF3584 PF12128.8 KFP06128.1 - 0.087 10.3 7.8 0.13 9.7 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3987 PF13148.6 KFP06128.1 - 0.12 11.3 3.0 0.18 10.8 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) UPF0242 PF06785.11 KFP06128.1 - 0.17 12.0 7.7 0.27 11.3 7.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 KFP06128.1 - 0.2 10.5 9.7 0.33 9.8 9.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein GCN5L1 PF06320.13 KFP06128.1 - 0.25 11.5 5.6 0.5 10.5 5.6 1.4 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) DUF5082 PF16888.5 KFP06128.1 - 0.55 10.5 8.0 8.1 6.7 2.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) GAS PF13851.6 KFP06128.1 - 0.77 9.1 11.8 1.4 8.2 11.8 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 KFP06128.1 - 0.79 9.8 14.4 1.8 8.6 14.4 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein FapA PF03961.13 KFP06128.1 - 0.79 8.3 4.0 1.1 7.8 4.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMF_TATA_bd PF12325.8 KFP06128.1 - 0.84 9.9 11.3 2.9 8.1 11.3 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ATG16 PF08614.11 KFP06128.1 - 1.3 9.2 14.0 5.2 7.2 2.0 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CC2-LZ PF16516.5 KFP06128.1 - 1.4 9.4 11.9 1.9 8.9 3.7 2.5 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator PRKG1_interact PF15898.5 KFP06128.1 - 1.5 9.8 9.0 3.7 8.5 9.0 1.7 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain CENP-H PF05837.12 KFP06128.1 - 1.8 9.0 9.5 4.6 7.7 9.5 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF4407 PF14362.6 KFP06128.1 - 6.9 5.9 8.0 16 4.7 8.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) NOT2_3_5 PF04153.18 KFP06129.1 - 3.2e-32 111.4 0.2 6.1e-32 110.5 0.2 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family CaKB PF03185.15 KFP06130.1 - 4.1e-56 189.8 0.1 4.7e-56 189.6 0.1 1.0 1 0 0 1 1 1 1 Calcium-activated potassium channel, beta subunit fn3 PF00041.21 KFP06131.1 - 5.7e-163 529.7 47.3 1.7e-12 47.5 0.5 18.6 19 0 0 19 19 19 16 Fibronectin type III domain Y_phosphatase PF00102.27 KFP06131.1 - 1.6e-78 263.5 0.2 3e-78 262.6 0.2 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase SdrD_B PF17210.3 KFP06131.1 - 3.4e-07 30.5 21.6 2.3 8.5 0.1 10.4 11 1 1 12 12 11 2 SdrD B-like domain Pur_ac_phosph_N PF16656.5 KFP06131.1 - 7.1e-07 29.7 35.6 2.2 8.9 0.2 13.1 12 2 0 12 12 10 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFP06131.1 - 0.00023 21.4 9.2 3.6 7.9 0.0 7.8 8 0 0 8 8 8 1 Interferon-alpha/beta receptor, fibronectin type III Y_phosphatase3 PF13350.6 KFP06131.1 - 0.00058 19.9 0.0 0.0014 18.6 0.0 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family Glyco_hydro_66 PF13199.6 KFP06131.1 - 0.00077 18.2 0.3 0.045 12.4 0.0 3.7 5 0 0 5 5 5 1 Glycosyl hydrolase family 66 DSPc PF00782.20 KFP06131.1 - 0.0048 16.7 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Big_4 PF07532.11 KFP06131.1 - 0.024 14.3 12.2 0.43 10.3 0.1 5.4 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 4) PTPlike_phytase PF14566.6 KFP06131.1 - 0.027 14.6 0.0 0.062 13.4 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate UPF0052 PF01933.18 KFP06131.1 - 0.032 13.5 0.0 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0052 PilA4 PF18682.1 KFP06131.1 - 4.4 7.7 9.1 70 3.9 0.1 6.3 5 1 1 6 6 6 0 Pilin A4 Y_phosphatase PF00102.27 KFP06132.1 - 3.4e-75 252.6 0.1 6.2e-75 251.8 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFP06132.1 - 0.0003 20.6 0.0 0.00075 19.3 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP06132.1 - 0.00044 20.3 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family CyRPA PF18638.1 KFP06132.1 - 0.028 13.6 0.1 0.043 13.0 0.1 1.2 1 0 0 1 1 1 0 Cysteine-Rich Protective Antigen 6 bladed domain PTPlike_phytase PF14566.6 KFP06132.1 - 0.033 14.3 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF1999 PF09390.10 KFP06132.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1999) LRR_8 PF13855.6 KFP06133.1 - 5.6e-72 237.4 36.1 1.9e-12 46.7 4.7 8.5 2 2 7 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 KFP06133.1 - 5.8e-41 137.8 41.1 8.3e-06 26.1 0.2 9.7 6 1 5 11 11 11 11 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP06133.1 - 3.7e-36 123.9 0.0 3e-13 49.9 0.0 4.7 2 1 3 5 5 5 4 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP06133.1 - 1.2e-14 54.2 10.9 0.0027 17.2 0.6 5.4 1 1 3 5 5 5 5 Leucine-rich repeat LRR_1 PF00560.33 KFP06133.1 - 1e-11 43.7 38.6 0.79 10.5 0.1 13.9 13 2 0 13 13 13 4 Leucine Rich Repeat 7tm_1 PF00001.21 KFP06133.1 - 1.2e-10 41.1 15.4 2.6e-10 40.1 15.4 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP06133.1 - 0.0027 17.4 7.6 0.0027 17.4 7.6 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx zf-C3H1 PF10650.9 KFP06134.1 - 6e-09 35.5 4.3 1.4e-08 34.3 4.3 1.7 1 0 0 1 1 1 1 Putative zinc-finger domain TPR_17 PF13431.6 KFP06134.1 - 1.9e-07 31.0 4.5 0.031 14.6 0.2 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP06134.1 - 3.3e-07 30.6 7.4 3 8.9 0.0 7.5 7 1 2 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFP06134.1 - 2e-06 28.2 4.4 0.06 13.9 0.0 6.5 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP06134.1 - 0.017 15.3 3.9 26 5.4 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFP06134.1 - 0.036 13.8 5.8 0.3 10.8 0.2 4.3 4 1 1 5 5 5 0 TPR repeat TPR_12 PF13424.6 KFP06134.1 - 0.15 12.3 5.5 1 9.7 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFP06134.1 - 0.2 11.5 2.0 55 3.8 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat RVT_1 PF00078.27 KFP06135.1 - 0.027 14.0 0.0 0.072 12.6 0.0 1.8 3 0 0 3 3 3 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF92 PF01940.16 KFP06136.1 - 1.9e-78 263.2 2.6 2.7e-78 262.6 2.6 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF92 S_4TM PF18159.1 KFP06136.1 - 0.55 9.5 0.0 0.55 9.5 0.0 2.1 2 1 0 2 2 2 0 SMODS-associating 4TM effector domain Ras PF00071.22 KFP06137.1 - 1.5e-43 148.2 0.1 1.8e-43 148.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP06137.1 - 1.7e-22 79.9 0.1 3.6e-22 78.8 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP06137.1 - 1e-09 38.1 0.1 1.2e-09 37.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP06137.1 - 0.00013 21.6 0.0 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFP06137.1 - 0.003 17.5 0.1 0.0056 16.6 0.1 1.4 1 1 0 1 1 1 1 RsgA GTPase PduV-EutP PF10662.9 KFP06137.1 - 0.039 13.7 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PH_RBD PF12068.8 KFP06138.1 - 2.5e-35 121.4 0.3 3.7e-35 120.9 0.3 1.3 1 0 0 1 1 1 1 Rab-binding domain (RBD) RabGAP-TBC PF00566.18 KFP06138.1 - 4.3e-12 46.1 1.2 7.1e-12 45.4 1.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain KELK PF15796.5 KFP06138.1 - 0.017 15.5 3.9 0.044 14.2 3.9 1.6 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase 7tm_1 PF00001.21 KFP06139.1 - 1.6e-18 67.0 7.3 6.8e-16 58.4 0.5 2.3 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP06139.1 - 0.00015 21.5 3.6 0.00015 21.5 3.6 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DCX PF03607.17 KFP06140.1 - 2.7e-37 126.7 0.0 5.9e-21 74.3 0.0 2.6 2 0 0 2 2 2 2 Doublecortin PLAT PF01477.23 KFP06141.1 - 1.3e-16 61.2 0.0 2.1e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 PLAT/LH2 domain XK-related PF09815.9 KFP06143.1 - 1.3e-105 353.2 26.5 1.5e-105 353.0 26.5 1.0 1 0 0 1 1 1 1 XK-related protein Acyltransferase PF01553.21 KFP06145.1 - 5e-08 32.6 0.0 1.2e-07 31.4 0.0 1.7 1 1 0 1 1 1 1 Acyltransferase DAGAT PF03982.13 KFP06145.1 - 6.6e-05 22.0 0.0 0.00011 21.2 0.0 1.6 1 1 0 1 1 1 1 Diacylglycerol acyltransferase Pkinase_Tyr PF07714.17 KFP06147.1 - 5.7e-96 320.8 0.0 7.3e-96 320.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP06147.1 - 6.5e-48 163.4 0.0 9.2e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFP06147.1 - 8.7e-24 83.4 0.0 1.8e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFP06147.1 - 2.8e-16 58.9 0.1 6.2e-16 57.7 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP06147.1 - 2.1e-08 33.7 0.4 7.8e-08 31.9 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KFP06147.1 - 2.1e-08 33.9 0.0 5.3e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFP06147.1 - 0.002 18.4 0.1 0.0041 17.4 0.1 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain Haspin_kinase PF12330.8 KFP06147.1 - 0.02 13.9 0.1 0.042 12.8 0.1 1.5 1 1 0 1 1 1 0 Haspin like kinase domain DUF2070 PF09843.9 KFP06147.1 - 0.12 10.7 0.0 0.16 10.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Kinesin PF00225.23 KFP06148.1 - 2.2e-96 322.7 0.2 3.8e-96 321.9 0.2 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFP06148.1 - 4.7e-16 59.0 1.8 2.3e-13 50.4 0.1 3.4 3 0 0 3 3 3 2 Microtubule binding FapA PF03961.13 KFP06148.1 - 0.13 10.9 1.5 0.22 10.1 1.5 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Ribosomal_S10 PF00338.22 KFP06149.1 - 4.7e-31 106.9 0.3 5.6e-31 106.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Pkinase PF00069.25 KFP06150.1 - 6.8e-47 160.0 0.0 9.4e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP06150.1 - 2.7e-41 141.6 0.0 3.1e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP06150.1 - 0.0024 17.3 0.0 0.0084 15.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFP06150.1 - 0.038 12.8 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase zf-H2C2_2 PF13465.6 KFP06151.1 - 2.7e-25 87.6 56.2 3.7e-05 23.9 1.0 8.5 8 0 0 8 8 8 8 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP06151.1 - 2e-24 84.1 58.0 0.00058 20.5 1.1 7.5 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP06151.1 - 5.4e-23 80.1 64.8 6.1e-05 23.3 1.4 7.6 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFP06151.1 - 1.6e-05 24.7 51.8 0.023 14.7 0.6 7.3 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP06151.1 - 2.3e-05 24.6 45.1 0.032 14.5 1.1 7.1 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP06151.1 - 0.00027 21.2 26.9 0.29 11.6 0.7 5.8 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFP06151.1 - 0.0021 18.3 30.4 0.038 14.3 10.3 4.3 1 1 2 3 3 3 2 C2H2-type zinc ribbon Acyltransf_C PF16076.5 KFP06151.1 - 0.0052 16.8 3.8 0.92 9.6 0.7 2.7 2 0 0 2 2 2 2 Acyltransferase C-terminus zf-C2H2_11 PF16622.5 KFP06151.1 - 0.035 13.9 0.0 0.035 13.9 0.0 6.6 8 0 0 8 8 8 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KFP06151.1 - 0.1 13.0 40.8 1.1 9.6 1.4 5.5 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KFP06151.1 - 2 8.3 8.7 1.2e+02 2.6 0.0 5.1 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-LITAF-like PF10601.9 KFP06151.1 - 7.3 6.9 14.9 0.25 11.6 2.4 3.7 3 1 0 3 3 3 0 LITAF-like zinc ribbon domain zf-Di19 PF05605.12 KFP06151.1 - 9.3 6.6 37.2 0.8 10.0 1.1 5.0 1 1 6 7 7 7 0 Drought induced 19 protein (Di19), zinc-binding MTCP1 PF08991.10 KFP06152.1 - 0.00068 19.8 0.7 0.00078 19.6 0.7 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 KFP06152.1 - 0.082 13.1 5.3 0.12 12.5 5.3 1.3 1 0 0 1 1 1 0 CHCH domain Trypsin PF00089.26 KFP06153.1 - 1.7e-60 204.6 0.0 1.9e-60 204.5 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFP06153.1 - 0.00025 21.4 0.1 0.00062 20.1 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 KFP06153.1 - 0.00051 21.0 0.0 0.00098 20.0 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Med26 PF08711.11 KFP06154.1 - 1.4e-14 53.9 0.2 4.7e-14 52.2 0.0 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Sulfotransfer_2 PF03567.14 KFP06155.1 - 2.1e-48 165.4 0.5 3e-48 164.9 0.5 1.2 1 0 0 1 1 1 1 Sulfotransferase family DUF3552 PF12072.8 KFP06155.1 - 0.69 9.3 4.9 1.2 8.5 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) PH PF00169.29 KFP06156.1 - 1.9e-10 41.2 0.2 2.5e-10 40.8 0.2 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFP06156.1 - 0.0068 16.8 0.2 0.022 15.1 0.2 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain TCRP1 PF14944.6 KFP06157.1 - 2.3e-95 319.2 58.1 3.6e-87 292.4 44.4 2.0 1 1 1 2 2 2 2 Tongue Cancer Chemotherapy Resistant Protein 1 DUF2076 PF09849.9 KFP06157.1 - 3.7 7.5 5.1 3.7 7.5 4.4 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) 7tm_1 PF00001.21 KFP06158.1 - 1.2e-31 110.1 17.4 1.4e-31 109.8 17.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP06158.1 - 0.0067 16.1 7.9 0.0067 16.1 7.9 2.3 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx DMT_YdcZ PF04657.13 KFP06158.1 - 0.0075 16.5 0.1 0.0075 16.5 0.1 2.7 2 1 0 3 3 3 1 Putative inner membrane exporter, YdcZ 7tm_1 PF00001.21 KFP06159.1 - 1.1e-25 90.4 24.4 1.4e-25 90.2 24.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) C1q PF00386.21 KFP06160.1 - 3.4e-40 137.2 0.4 4.3e-40 136.9 0.4 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFP06160.1 - 6.1e-11 41.9 23.5 1.5e-10 40.6 23.5 1.6 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) BclA_C PF18573.1 KFP06160.1 - 0.01 15.7 0.1 0.014 15.3 0.1 1.1 1 0 0 1 1 1 0 BclA C-terminal domain Glyco_transf_29 PF00777.18 KFP06161.1 - 2.1e-37 129.0 0.1 4.5e-37 127.9 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) MurB_C PF02873.16 KFP06161.1 - 0.08 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain MYEOV2 PF15004.6 KFP06162.1 - 4.8e-34 116.6 6.9 5.3e-34 116.5 6.9 1.0 1 0 0 1 1 1 1 Myeloma-overexpressed-like Sushi PF00084.20 KFP06163.1 - 1.7e-15 57.4 12.0 1e-08 35.6 0.4 2.9 3 0 0 3 3 3 2 Sushi repeat (SCR repeat) Sushi PF00084.20 KFP06164.1 - 3.4e-16 59.6 1.1 2.2e-11 44.2 0.2 2.1 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) Sushi PF00084.20 KFP06165.1 - 5.3e-34 116.6 9.3 1.1e-12 48.3 0.7 3.1 2 1 1 3 3 3 3 Sushi repeat (SCR repeat) HRM PF02793.22 KFP06165.1 - 0.00049 20.3 4.9 0.18 12.1 0.2 3.2 3 0 0 3 3 3 2 Hormone receptor domain CBM_14 PF01607.24 KFP06165.1 - 0.15 12.2 3.7 6.7 7.0 0.1 3.0 3 1 0 3 3 3 0 Chitin binding Peritrophin-A domain cEGF PF12662.7 KFP06165.1 - 1.9 8.5 7.4 3.7 7.6 0.2 3.5 3 1 0 3 3 3 0 Complement Clr-like EGF-like Sushi PF00084.20 KFP06166.1 - 1e-73 243.8 37.2 1.1e-12 48.3 2.1 7.1 7 0 0 7 7 7 7 Sushi repeat (SCR repeat) cEGF PF12662.7 KFP06166.1 - 0.00075 19.4 21.1 0.78 9.7 0.1 6.9 7 0 0 7 7 7 3 Complement Clr-like EGF-like DUF281 PF03436.13 KFP06166.1 - 0.12 12.8 2.7 0.62 10.5 0.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF281) Sushi PF00084.20 KFP06167.1 - 2.8e-59 197.6 28.5 5.1e-11 43.0 0.3 6.1 6 0 0 6 6 6 6 Sushi repeat (SCR repeat) HRM PF02793.22 KFP06167.1 - 3.3e-06 27.3 26.0 0.11 12.8 0.2 6.3 5 1 0 5 5 5 3 Hormone receptor domain C4bp_oligo PF18453.1 KFP06167.1 - 0.00026 21.1 2.5 0.00078 19.6 2.5 1.8 1 0 0 1 1 1 1 Oligomerization domain of C4b-binding protein alpha Sushi PF00084.20 KFP06168.1 - 3.7e-14 53.1 1.7 9.8e-10 38.9 0.7 2.0 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) 6PF2K PF01591.18 KFP06169.1 - 4e-102 340.3 1.4 5.6e-102 339.8 1.4 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KFP06169.1 - 1.1e-41 142.7 0.0 1.4e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KFP06169.1 - 5.1e-08 33.2 0.0 1.3e-07 31.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KFP06169.1 - 5.1e-05 22.9 0.2 9.2e-05 22.0 0.0 1.4 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_17 PF13207.6 KFP06169.1 - 0.0061 17.0 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain His_Phos_2 PF00328.22 KFP06169.1 - 0.048 13.0 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) AAA_18 PF13238.6 KFP06169.1 - 0.094 13.3 0.0 0.27 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain OTU PF02338.19 KFP06170.1 - 2.6e-05 24.7 0.0 4.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease zf-C2H2_2 PF12756.7 KFP06170.1 - 0.036 14.4 0.0 0.073 13.4 0.0 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFP06170.1 - 0.58 10.6 2.4 3.8 8.0 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type SARG PF15385.6 KFP06171.1 - 1.9e-99 334.4 45.2 2.8e-53 182.0 10.3 3.1 1 1 2 3 3 3 3 Specifically androgen-regulated gene protein V-set PF07686.17 KFP06172.1 - 4.2e-52 174.9 13.3 8.5e-13 48.4 0.2 5.4 5 0 0 5 5 5 5 Immunoglobulin V-set domain ig PF00047.25 KFP06172.1 - 8.5e-14 51.5 10.2 7.3e-06 26.1 0.4 7.1 8 0 0 8 8 8 3 Immunoglobulin domain Ig_3 PF13927.6 KFP06172.1 - 8.3e-11 42.3 15.7 0.0095 16.5 1.2 5.7 5 0 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 KFP06172.1 - 8.4e-10 38.6 3.0 0.34 11.0 0.1 5.8 5 2 0 5 5 5 4 Immunoglobulin I-set domain Ig_4 PF16680.5 KFP06172.1 - 1.2e-06 28.7 0.2 0.56 10.5 0.1 5.6 5 0 0 5 5 5 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFP06172.1 - 0.00048 20.1 0.1 2.7 8.1 0.0 4.7 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain DUF3377 PF11857.8 KFP06172.1 - 0.17 11.8 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Pkinase PF00069.25 KFP06173.1 - 1.9e-51 175.0 0.0 2.9e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP06173.1 - 4.8e-24 85.0 0.0 6.9e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFP06173.1 - 1.8e-06 27.5 0.0 2.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFP06173.1 - 0.0018 17.7 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP06173.1 - 0.0062 15.4 0.0 0.0099 14.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 KFP06173.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 KFP06174.1 - 2.9e-58 197.3 0.0 4.3e-58 196.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP06174.1 - 2.5e-21 76.1 0.1 5.7e-21 75.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFP06174.1 - 2.1e-05 24.6 0.0 0.0027 17.6 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KFP06174.1 - 0.0022 17.6 2.3 0.0026 17.4 0.4 1.9 2 0 0 2 2 2 1 RIO1 family YrbL-PhoP_reg PF10707.9 KFP06174.1 - 0.0035 16.9 1.2 0.14 11.7 0.0 2.4 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Choline_kinase PF01633.20 KFP06174.1 - 0.0035 17.0 1.5 0.0064 16.1 1.5 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KFP06174.1 - 0.0068 15.8 0.3 0.012 15.0 0.3 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Staphylcoagulse PF04022.12 KFP06174.1 - 0.051 13.1 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 Staphylocoagulase repeat Nore1-SARAH PF16517.5 KFP06175.1 - 1.4e-18 66.5 5.4 1.4e-18 66.5 5.4 2.5 2 0 0 2 2 2 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain RA PF00788.23 KFP06175.1 - 1.5e-16 60.8 0.1 3.8e-16 59.5 0.0 1.7 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain Pkinase PF00069.25 KFP06176.1 - 3e-47 161.2 0.0 4.2e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain TBK1_ULD PF18396.1 KFP06176.1 - 1.8e-31 107.9 1.3 3.1e-31 107.1 1.3 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Pkinase_Tyr PF07714.17 KFP06176.1 - 2.9e-28 98.9 0.0 4e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase TBK1_CCD1 PF18394.1 KFP06176.1 - 3.7e-08 33.2 0.1 2.7e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 TANK-binding kinase 1 coiled-coil domain 1 Kinase-like PF14531.6 KFP06176.1 - 4.3e-05 23.0 0.0 0.0044 16.4 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFP06176.1 - 6.1e-05 22.0 0.0 0.0014 17.4 0.0 2.2 1 1 0 2 2 2 1 Fungal protein kinase DUF4892 PF16234.5 KFP06176.1 - 0.028 13.9 0.0 0.074 12.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4892) APH PF01636.23 KFP06176.1 - 0.098 12.6 0.0 1.8 8.4 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family RhoGAP PF00620.27 KFP06177.1 - 4.1e-35 120.8 1.4 5.7e-34 117.1 0.0 3.5 2 2 1 3 3 3 1 RhoGAP domain FCH PF00611.23 KFP06177.1 - 1.8e-18 66.6 2.7 8.6e-18 64.4 2.7 2.3 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KFP06177.1 - 1e-09 37.8 0.0 1.9e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP06177.1 - 1.4e-08 34.2 0.0 3.4e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFP06177.1 - 1.1e-07 31.6 0.0 2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF4164 PF13747.6 KFP06177.1 - 0.94 9.8 8.5 0.41 11.0 1.9 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) FlaC_arch PF05377.11 KFP06177.1 - 0.99 9.8 13.2 0.1 13.0 2.3 3.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) FAM72 PF14976.6 KFP06178.1 - 4.7e-37 127.3 0.1 5.1e-37 127.2 0.1 1.0 1 0 0 1 1 1 1 FAM72 protein 7tm_1 PF00001.21 KFP06179.1 - 3.2e-52 177.5 3.1 3.7e-52 177.2 3.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP06179.1 - 7.7e-11 41.9 0.8 1.1e-10 41.3 0.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP06179.1 - 6.8e-06 26.0 1.0 1.2e-05 25.2 1.0 1.4 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srv PF10323.9 KFP06179.1 - 8.7e-06 25.3 0.0 1.5e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Srg PF02118.21 KFP06179.1 - 9.8 5.7 12.1 0.048 13.3 2.4 2.0 2 1 0 2 2 2 0 Srg family chemoreceptor Asp PF00026.23 KFP06180.1 - 6.8e-121 403.5 0.1 7.7e-121 403.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFP06180.1 - 1.4e-14 54.7 3.6 1.2e-10 41.9 0.1 2.6 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal A1_Propeptide PF07966.12 KFP06180.1 - 2e-05 24.4 0.2 3.1e-05 23.7 0.2 1.3 1 0 0 1 1 1 1 A1 Propeptide Asp_protease_2 PF13650.6 KFP06180.1 - 0.00068 20.2 0.2 0.75 10.5 0.1 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KFP06180.1 - 0.018 14.8 0.0 0.09 12.6 0.0 2.0 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Ras PF00071.22 KFP06181.1 - 1.2e-32 112.8 0.0 1.3e-32 112.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP06181.1 - 8.6e-13 48.6 0.0 1.2e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP06181.1 - 2.3e-08 33.7 0.0 2.5e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP06181.1 - 0.0049 16.4 0.0 0.02 14.4 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 KFP06181.1 - 0.085 12.9 0.0 0.097 12.7 0.0 1.2 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Sulfate_transp PF00916.20 KFP06182.1 - 4.4e-77 259.4 17.0 1e-76 258.2 17.0 1.6 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFP06182.1 - 5.7e-25 87.2 0.0 9.2e-25 86.6 0.0 1.3 1 0 0 1 1 1 1 STAS domain Peptidase_M20 PF01546.28 KFP06183.1 - 5.8e-31 107.8 0.0 9.4e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFP06183.1 - 3.2e-17 62.4 0.0 5.1e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain MgtE PF01769.16 KFP06184.1 - 5.2e-55 185.1 24.8 1.9e-30 105.8 3.4 2.8 3 0 0 3 3 3 2 Divalent cation transporter Ras PF00071.22 KFP06185.1 - 1.8e-45 154.5 0.0 2.1e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP06185.1 - 8.6e-32 109.9 0.0 1.3e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP06185.1 - 6.3e-15 55.1 0.1 8.1e-15 54.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family TniB PF05621.11 KFP06185.1 - 0.0001 21.7 0.0 0.00019 20.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein Gtr1_RagA PF04670.12 KFP06185.1 - 0.00013 21.4 0.1 0.00024 20.5 0.1 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP06185.1 - 0.00023 21.2 0.0 0.00032 20.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFP06185.1 - 0.00041 19.8 0.0 0.00061 19.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KFP06185.1 - 0.0024 17.6 0.0 0.0056 16.4 0.0 1.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 KFP06185.1 - 0.0031 17.4 0.1 0.44 10.3 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein DLIC PF05783.11 KFP06185.1 - 0.01 14.7 0.0 0.81 8.5 0.0 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) MMR_HSR1_Xtn PF16897.5 KFP06185.1 - 0.016 15.2 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_16 PF13191.6 KFP06185.1 - 0.031 14.7 0.0 0.046 14.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KFP06185.1 - 0.07 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 KFP06185.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MFS_1 PF07690.16 KFP06187.1 - 5.5e-13 48.6 33.2 1e-09 37.8 10.4 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 KFP06187.1 - 3.9e-07 29.0 2.3 3.9e-07 29.0 2.3 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein CytochromB561_N PF09786.9 KFP06187.1 - 0.69 8.8 3.5 1 8.3 3.5 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Ets PF00178.22 KFP06188.1 - 1.2e-35 121.8 1.9 1.8e-35 121.2 1.9 1.3 1 0 0 1 1 1 1 Ets-domain MFS_1 PF07690.16 KFP06189.1 - 3.4e-13 49.3 33.5 8.4e-08 31.5 19.7 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 KFP06190.1 - 1.5e-69 234.4 0.0 1.8e-69 234.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP06190.1 - 6.6e-33 114.1 0.0 9.4e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP06190.1 - 1.3e-05 24.7 0.0 2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFP06190.1 - 7.7e-05 21.8 0.1 0.00027 20.0 0.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFP06190.1 - 0.0035 16.7 0.1 0.0086 15.5 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KFP06190.1 - 0.021 13.9 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KFP06190.1 - 0.092 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Vac14_Fig4_bd PF11916.8 KFP06191.1 - 7.6e-80 266.8 9.6 1.2e-79 266.1 9.6 1.3 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding IMD PF08397.11 KFP06192.1 - 7.8e-102 339.3 2.4 1e-101 338.9 2.4 1.1 1 0 0 1 1 1 1 IRSp53/MIM homology domain YlqD PF11068.8 KFP06192.1 - 2.1 8.7 5.9 3.7 7.9 5.9 1.3 1 0 0 1 1 1 0 YlqD protein IL34 PF15036.6 KFP06193.1 - 3.2e-43 147.5 1.6 3.5e-43 147.4 1.6 1.0 1 0 0 1 1 1 1 Interleukin 34 COG4 PF08318.12 KFP06194.1 - 2.6e-100 335.8 6.4 5.1e-100 334.8 6.4 1.5 1 0 0 1 1 1 1 COG4 transport protein RINT1_TIP1 PF04437.13 KFP06194.1 - 5.9e-05 22.2 0.1 0.00013 21.0 0.1 1.6 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Bac_thur_toxin PF01338.18 KFP06194.1 - 0.07 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacillus thuringiensis toxin Fucokinase PF07959.12 KFP06195.1 - 1.7e-100 336.9 0.0 2.1e-100 336.6 0.0 1.1 1 0 0 1 1 1 1 L-fucokinase GHMP_kinases_C PF08544.13 KFP06195.1 - 1.2e-06 28.8 0.0 4.1e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 KFP06195.1 - 3.2e-05 24.1 0.4 9.9e-05 22.5 0.4 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain Glyco_transf_29 PF00777.18 KFP06196.1 - 1.1e-81 274.2 0.0 1.3e-81 274.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) G_glu_transpept PF01019.21 KFP06196.1 - 0.0065 15.3 0.0 0.0087 14.9 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase GCV_T PF01571.21 KFP06197.1 - 1.1e-68 231.3 0.0 1.8e-68 230.7 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 KFP06197.1 - 3.6e-57 194.5 0.1 5.6e-57 193.9 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAO_M PF16350.5 KFP06197.1 - 4.1e-15 55.9 0.3 1.1e-14 54.5 0.0 1.9 2 0 0 2 2 1 1 FAD dependent oxidoreductase central domain GCV_T_C PF08669.11 KFP06197.1 - 4.1e-14 52.3 0.0 2.1e-13 50.0 0.0 2.3 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain FAD_binding_2 PF00890.24 KFP06197.1 - 1.9e-06 27.3 0.6 6.1e-06 25.6 0.9 1.7 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KFP06197.1 - 5.9e-06 25.7 0.2 0.013 14.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFP06197.1 - 6.8e-05 22.3 0.9 0.28 10.4 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KFP06197.1 - 0.00012 21.5 0.3 0.27 10.6 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Trp_halogenase PF04820.14 KFP06197.1 - 0.00046 19.2 1.8 0.03 13.2 0.1 2.2 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KFP06197.1 - 0.0074 15.6 2.7 0.16 11.2 3.0 2.5 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KFP06197.1 - 0.018 15.3 0.2 0.063 13.5 0.2 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFP06197.1 - 0.018 14.3 1.1 0.42 9.8 0.1 2.2 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 KFP06197.1 - 0.023 15.2 1.6 6 7.5 0.2 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFP06197.1 - 0.028 13.1 0.5 0.079 11.6 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 KFP06197.1 - 0.1 12.9 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Cys_rich_FGFR PF00839.17 KFP06198.1 - 7.2e-192 621.8 115.8 2e-17 63.1 1.8 15.2 15 0 0 15 15 15 15 Cysteine rich repeat CENP-F_leu_zip PF10473.9 KFP06198.1 - 0.033 14.2 0.7 0.033 14.2 0.7 3.6 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tox-HDC PF15656.6 KFP06198.1 - 0.043 14.0 0.5 1.9 8.7 0.0 3.5 3 1 1 5 5 5 0 Toxin with a H, D/N and C signature IFT43 PF15305.6 KFP06198.1 - 0.052 13.7 0.4 0.21 11.8 0.1 2.1 2 0 0 2 2 2 0 Intraflagellar transport protein 43 DUF445 PF04286.12 KFP06198.1 - 5 6.8 8.5 3.9 7.2 5.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Pkinase_Tyr PF07714.17 KFP06199.1 - 9.5e-42 143.1 0.0 4.3e-40 137.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFP06199.1 - 1.8e-28 99.7 0.0 5.1e-28 98.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain RPW8 PF05659.11 KFP06199.1 - 0.00087 19.0 0.5 0.00087 19.0 0.5 1.8 2 0 0 2 2 2 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 FA_hydroxylase PF04116.13 KFP06200.1 - 2e-16 60.5 11.8 2e-16 60.5 11.8 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 KFP06200.1 - 0.026 14.7 0.5 0.046 13.9 0.5 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region TMEM189_B_dmain PF10520.9 KFP06200.1 - 0.097 12.8 4.1 0.36 10.9 0.9 2.2 2 0 0 2 2 2 0 B domain of TMEM189, localisation domain COX14 PF14880.6 KFP06200.1 - 0.1 12.4 8.7 0.07 13.0 3.5 2.4 2 0 0 2 2 2 0 Cytochrome oxidase c assembly WD40 PF00400.32 KFP06201.1 - 6.2e-13 49.0 21.5 1.6e-05 25.6 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 KFP06201.1 - 2.5e-10 39.8 12.3 2.5e-10 39.8 12.3 2.5 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 KFP06201.1 - 8.5e-07 29.2 3.7 8.5e-07 29.2 3.7 2.4 1 1 1 2 2 2 1 Zinc-ribbon like family ANAPC4_WD40 PF12894.7 KFP06201.1 - 0.0092 16.3 0.9 1.2 9.4 0.0 3.5 1 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_2 PF13639.6 KFP06201.1 - 0.46 10.8 14.6 0.031 14.6 5.5 3.1 2 0 0 2 2 2 0 Ring finger domain zf-rbx1 PF12678.7 KFP06201.1 - 4.6 7.6 16.3 0.35 11.2 10.7 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KFP06202.1 - 6.7e-11 42.4 9.1 1.9e-09 37.7 4.4 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 KFP06202.1 - 2.1e-06 27.5 6.2 5.2e-05 23.0 3.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFP06202.1 - 6.6e-06 25.8 4.4 6.6e-06 25.8 4.4 2.3 2 0 0 2 2 2 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 KFP06202.1 - 0.00043 19.9 3.2 0.00043 19.9 3.2 2.0 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 KFP06202.1 - 0.0016 18.5 4.6 0.0016 18.5 4.6 2.3 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING-like PF08746.11 KFP06202.1 - 0.002 18.4 5.3 0.0082 16.4 2.0 2.2 2 0 0 2 2 2 1 RING-like domain zf-C3HC4_3 PF13920.6 KFP06202.1 - 0.002 17.9 7.7 0.05 13.5 2.4 2.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KFP06202.1 - 0.0026 17.9 6.3 0.075 13.2 3.4 2.5 2 1 0 2 2 2 1 FANCL C-terminal domain zf-C3HC4 PF00097.25 KFP06202.1 - 0.0032 17.3 9.6 0.013 15.4 4.1 2.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP06202.1 - 0.0039 17.1 6.6 0.13 12.3 2.7 2.2 2 0 0 2 2 2 2 zinc-RING finger domain zf-rbx1 PF12678.7 KFP06202.1 - 0.0045 17.2 11.4 0.33 11.3 11.4 2.8 1 1 1 2 2 2 1 RING-H2 zinc finger domain RINGv PF12906.7 KFP06202.1 - 0.0054 16.8 6.0 0.03 14.4 2.2 2.5 2 1 0 2 2 2 1 RING-variant domain RNF220 PF15926.5 KFP06202.1 - 0.0095 15.6 0.1 0.012 15.3 0.1 1.2 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 Prok-RING_4 PF14447.6 KFP06202.1 - 0.013 15.3 7.7 1.2 9.0 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 KFP06202.1 - 0.015 15.2 7.4 0.54 10.2 2.9 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-Di19 PF05605.12 KFP06202.1 - 0.026 14.8 2.3 0.037 14.3 0.1 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 KFP06202.1 - 0.035 13.7 0.2 0.084 12.5 0.2 1.7 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger PRP21_like_P PF12230.8 KFP06202.1 - 0.066 13.1 0.0 0.077 12.9 0.0 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein C1_1 PF00130.22 KFP06202.1 - 0.89 9.5 6.3 15 5.6 0.1 2.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_4 PF14570.6 KFP06202.1 - 1 9.2 9.5 7.1 6.5 4.3 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FAD-oxidase_C PF02913.19 KFP06203.1 - 6e-48 163.7 0.0 8.5e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KFP06203.1 - 4.8e-08 32.8 0.0 1.1e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain Anth_Ig PF05587.13 KFP06204.1 - 8.5e-44 148.0 0.7 1.6e-43 147.2 0.5 1.5 2 0 0 2 2 2 1 Anthrax receptor extracellular domain VWA PF00092.28 KFP06204.1 - 9.6e-25 87.8 0.0 1.2e-24 87.5 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFP06204.1 - 2.3e-10 41.1 0.0 5.5e-10 39.8 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KFP06204.1 - 1.5e-05 24.5 0.0 2.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein RhoGAP PF00620.27 KFP06205.1 - 2.1e-43 147.8 1.8 1.3e-42 145.2 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 KFP06205.1 - 5.5e-20 71.8 0.5 1.4e-19 70.5 0.0 2.0 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 KFP06205.1 - 9.9e-05 22.6 0.0 0.0049 17.1 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain Nsp1_C PF05064.13 KFP06205.1 - 0.019 14.8 12.6 0.024 14.4 10.8 2.0 2 0 0 2 2 2 0 Nsp1-like C-terminal region CENP-F_leu_zip PF10473.9 KFP06205.1 - 0.045 13.8 22.7 0.085 12.9 22.7 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PH_11 PF15413.6 KFP06205.1 - 0.11 12.9 10.3 0.18 12.2 5.1 2.9 2 1 0 2 2 2 0 Pleckstrin homology domain PH_9 PF15410.6 KFP06205.1 - 0.45 10.9 2.8 2.4 8.5 0.1 2.9 3 0 0 3 3 3 0 Pleckstrin homology domain Jnk-SapK_ap_N PF09744.9 KFP06205.1 - 0.6 10.3 21.1 0.35 11.1 11.5 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 KFP06205.1 - 2.7 8.5 18.0 6.3 7.3 18.0 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region Not3 PF04065.15 KFP06205.1 - 2.9 7.2 21.9 0.11 11.9 15.5 1.8 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component CTP_transf_1 PF01148.20 KFP06206.1 - 2.8e-87 292.9 21.6 3.4e-87 292.6 21.6 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family PCNA_C PF02747.15 KFP06207.1 - 6e-64 214.0 0.0 1.4e-63 212.8 0.0 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 KFP06207.1 - 1.2e-58 196.3 0.7 2.4e-58 195.3 0.7 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.16 KFP06207.1 - 1.8e-07 30.5 0.0 4.6e-06 25.9 0.0 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 KFP06207.1 - 7.8e-07 28.8 0.0 9.8e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 KFP06207.1 - 0.004 16.3 0.0 0.02 14.0 0.0 2.1 1 1 0 1 1 1 1 Hus1-like protein DUF872 PF05915.12 KFP06208.1 - 3.8e-21 75.4 0.4 4.4e-21 75.2 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) Neurensin PF14927.6 KFP06208.1 - 0.0041 16.8 0.6 0.13 12.0 0.6 2.0 1 1 0 1 1 1 1 Neurensin DUF2207 PF09972.9 KFP06208.1 - 0.0078 15.0 0.4 0.0088 14.9 0.4 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF3040 PF11239.8 KFP06208.1 - 0.05 13.9 0.1 0.069 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF308 PF03729.13 KFP06208.1 - 0.19 12.1 11.2 0.79 10.1 9.6 2.0 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) Saf_2TM PF18303.1 KFP06208.1 - 1.5 8.4 4.4 1.2 8.8 0.6 2.0 1 1 0 2 2 2 0 SAVED-fused 2TM effector domain Xan_ur_permease PF00860.20 KFP06209.1 - 3.1e-92 309.3 20.6 4.5e-92 308.7 20.6 1.2 1 0 0 1 1 1 1 Permease family Nore1-SARAH PF16517.5 KFP06210.1 - 7.5e-16 57.8 6.7 2.2e-15 56.2 6.7 1.9 1 0 0 1 1 1 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain RA PF00788.23 KFP06210.1 - 2e-13 50.7 0.0 4e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ras_bdg_2 PF14847.6 KFP06210.1 - 0.029 14.7 0.0 0.082 13.3 0.0 1.8 1 0 0 1 1 1 0 Ras-binding domain of Byr2 Prominin PF05478.11 KFP06211.1 - 2.1e-130 436.2 0.0 2.6e-130 435.9 0.0 1.0 1 0 0 1 1 1 1 Prominin Peptidase_S41_N PF11918.8 KFP06211.1 - 0.12 12.7 0.4 2.4 8.4 0.3 2.2 2 0 0 2 2 2 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP JAB PF01398.21 KFP06212.1 - 1.7e-20 73.2 0.0 1.7e-20 73.2 0.0 2.1 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 KFP06212.1 - 5.8e-20 71.6 0.2 5.8e-20 71.6 0.2 2.0 2 1 1 3 3 3 1 USP8 dimerisation domain Prok-JAB PF14464.6 KFP06212.1 - 1.4e-06 28.1 0.5 6.1e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain Actin PF00022.19 KFP06213.1 - 3.4e-149 496.9 0.0 1.1e-148 495.2 0.0 1.7 1 1 0 1 1 1 1 Actin dNK PF01712.19 KFP06214.1 - 6.1e-30 104.6 0.0 6.7e-30 104.5 0.0 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 KFP06214.1 - 0.038 14.5 0.8 0.094 13.3 0.3 1.8 1 1 1 2 2 2 0 AAA domain Yae1_N PF09811.9 KFP06215.1 - 7.7e-18 63.9 63.5 1.8e+04 -28.3 63.5 6.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Tet_JBP PF12851.7 KFP06216.1 - 2.5e-106 355.8 0.1 4.4e-105 351.7 0.1 2.4 1 1 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Ras PF00071.22 KFP06217.1 - 1.4e-43 148.3 0.5 1.6e-43 148.1 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP06217.1 - 5.4e-14 52.4 0.0 1.1e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP06217.1 - 3e-05 23.5 0.1 3.2e-05 23.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP06217.1 - 0.00014 21.5 0.1 0.00016 21.2 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFP06217.1 - 0.0023 17.9 0.1 0.0044 16.9 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase Ubiquitin_5 PF18037.1 KFP06218.1 - 3.9e-34 116.9 2.7 5.3e-34 116.5 1.2 2.0 2 0 0 2 2 2 1 Ubiquitin-like domain UBA PF00627.31 KFP06218.1 - 1.3e-29 101.6 0.0 2.3e-09 37.0 0.0 3.7 3 0 0 3 3 3 3 UBA/TS-N domain HOIP-UBA PF16678.5 KFP06218.1 - 3.3e-07 30.4 6.7 0.00017 21.6 0.3 3.7 3 1 1 4 4 4 2 HOIP UBA domain pair UBA_4 PF14555.6 KFP06218.1 - 2.2e-05 24.2 0.1 0.23 11.3 0.1 3.5 3 0 0 3 3 3 2 UBA-like domain ubiquitin PF00240.23 KFP06218.1 - 0.00029 20.5 1.0 0.002 17.8 0.8 2.5 2 0 0 2 2 2 1 Ubiquitin family TPR_2 PF07719.17 KFP06218.1 - 0.013 15.6 8.4 1.3 9.3 0.4 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFP06218.1 - 0.025 14.8 6.5 0.77 10.1 0.1 3.8 3 1 2 5 5 4 0 Tetratricopeptide repeat RuvA_C PF07499.13 KFP06218.1 - 0.053 14.0 0.0 26 5.4 0.0 3.3 3 0 0 3 3 3 0 RuvA, C-terminal domain SPO22 PF08631.10 KFP06218.1 - 0.19 11.2 3.4 0.2 11.1 0.8 2.3 2 1 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like UBA_3 PF09288.10 KFP06218.1 - 0.37 10.6 4.3 12 5.8 0.0 3.8 4 0 0 4 4 4 0 Fungal ubiquitin-associated domain TPR_8 PF13181.6 KFP06218.1 - 1.2 9.5 4.5 5.8 7.4 0.3 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFP06218.1 - 1.4 8.9 4.3 6.3 6.8 0.3 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4682 PF15733.5 KFP06219.1 - 1.8e-21 77.1 0.0 2.8e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4682) FGGY_N PF00370.21 KFP06220.1 - 7.1e-19 68.3 0.0 7.3e-12 45.4 0.0 2.4 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KFP06220.1 - 8.4e-06 25.7 0.0 2.7e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_C PF02782.16 KFP06221.1 - 1.6e-09 37.8 0.0 1.9e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Phi29_Phage_SSB PF17427.2 KFP06221.1 - 0.061 13.5 0.0 0.065 13.4 0.0 1.1 1 0 0 1 1 1 0 Phage Single-stranded DNA-binding protein Pkinase PF00069.25 KFP06224.1 - 3.9e-31 108.4 0.0 6.2e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP06224.1 - 5.6e-26 91.4 0.0 9e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Activin_recp PF01064.23 KFP06224.1 - 2.2e-09 38.2 14.2 2.2e-09 38.2 14.2 1.9 2 0 0 2 2 2 1 Activin types I and II receptor domain Pkinase_fungal PF17667.1 KFP06224.1 - 0.00081 18.3 0.0 0.0015 17.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KFP06224.1 - 0.18 11.4 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Toxin_TOLIP PF00087.21 KFP06224.1 - 4.4 7.6 14.1 0.51 10.6 9.6 1.8 2 0 0 2 2 2 0 Snake toxin and toxin-like protein Endonuclease_NS PF01223.23 KFP06225.1 - 1.3e-59 201.7 0.0 1.7e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Exog_C PF18026.1 KFP06225.1 - 8.6e-28 96.1 0.6 1.6e-27 95.3 0.6 1.5 1 0 0 1 1 1 1 Endo/exonuclease (EXOG) C-terminal domain UQ_con PF00179.26 KFP06226.1 - 4.5e-48 162.4 0.1 5e-48 162.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFP06226.1 - 0.011 16.1 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 KFP06226.1 - 0.021 14.5 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 KFP06226.1 - 0.054 13.4 0.1 0.086 12.7 0.1 1.4 1 1 0 1 1 1 0 UEV domain TMEM173 PF15009.6 KFP06227.1 - 7.2e-108 360.2 0.5 9.3e-108 359.8 0.5 1.1 1 0 0 1 1 1 1 Transmembrane protein 173 PRMT5_TIM PF17285.2 KFP06227.1 - 0.0032 16.7 0.0 0.0047 16.2 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain LRR_4 PF12799.7 KFP06228.1 - 6.3e-17 61.4 16.0 1.9e-06 28.1 1.2 5.0 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP06228.1 - 2.2e-14 52.9 14.7 1.8e-06 27.6 2.6 4.6 2 2 2 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 KFP06228.1 - 8e-08 31.7 7.4 0.53 10.5 0.0 6.7 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 KFP06228.1 - 0.00011 22.3 17.8 1.2 10.0 0.4 6.7 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_9 PF14580.6 KFP06228.1 - 0.0057 16.2 0.1 2.9 7.4 0.1 2.4 2 0 0 2 2 2 2 Leucine-rich repeat HEAT PF02985.22 KFP06229.1 - 0.011 15.9 5.7 3.8 8.0 0.1 5.0 4 1 1 5 5 5 0 HEAT repeat Tti2 PF10521.9 KFP06229.1 - 0.023 14.2 1.0 2.4 7.6 0.1 2.7 2 1 0 2 2 2 0 Tti2 family HEAT_EZ PF13513.6 KFP06229.1 - 0.028 14.9 0.1 0.028 14.9 0.1 4.8 5 1 1 6 6 6 0 HEAT-like repeat Arm PF00514.23 KFP06229.1 - 0.19 11.8 0.2 0.19 11.8 0.2 7.0 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KFP06229.1 - 0.19 12.1 4.4 60 4.1 0.0 3.9 2 1 1 3 3 3 0 HEAT repeats L51_S25_CI-B8 PF05047.16 KFP06230.1 - 4.7e-17 61.7 0.0 5.6e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain WD40 PF00400.32 KFP06231.1 - 2.9e-15 56.4 5.6 0.001 19.9 0.0 7.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP06231.1 - 1.7e-10 41.0 0.0 0.016 15.5 0.0 3.9 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KFP06231.1 - 0.00056 20.3 0.3 3.9 8.1 0.0 4.4 5 0 0 5 5 5 1 PQQ-like domain WD40_like PF17005.5 KFP06231.1 - 0.011 15.1 0.0 0.46 9.8 0.0 2.6 2 1 1 3 3 3 0 WD40-like domain Ge1_WD40 PF16529.5 KFP06231.1 - 0.11 11.5 0.0 16 4.3 0.0 3.0 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KFP06231.1 - 0.13 11.0 0.0 14 4.3 0.0 2.2 1 1 0 2 2 2 0 Nup133 N terminal like RRM_1 PF00076.22 KFP06232.1 - 5.1e-05 23.0 0.0 7.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) B12-binding_2 PF02607.17 KFP06232.1 - 0.023 15.1 0.0 0.023 15.1 0.0 1.2 1 0 0 1 1 1 0 B12 binding domain tRNA-synt_His PF13393.6 KFP06233.1 - 4.4e-31 108.3 0.0 6.7e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KFP06233.1 - 9.3e-14 51.4 0.0 1.8e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 KFP06233.1 - 8.8e-05 22.1 0.0 0.00012 21.7 0.0 1.1 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs zf-C2H2_jaz PF12171.8 KFP06234.1 - 8e-07 29.2 1.5 8e-07 29.2 1.5 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP06234.1 - 1.6e-06 28.3 1.4 2.5e-06 27.7 1.4 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SNRNP27 PF08648.12 KFP06234.1 - 9.7e-05 22.4 0.3 9.7e-05 22.4 0.3 2.5 4 0 0 4 4 4 1 U4/U6.U5 small nuclear ribonucleoproteins zf-U1 PF06220.12 KFP06234.1 - 0.00015 21.4 1.0 0.00026 20.7 1.0 1.4 1 0 0 1 1 1 1 U1 zinc finger Cgr1 PF03879.14 KFP06234.1 - 0.014 15.7 16.8 0.014 15.7 16.8 2.1 2 0 0 2 2 2 0 Cgr1 family DUF4250 PF14056.6 KFP06234.1 - 0.046 13.7 0.4 0.13 12.3 0.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4250) zf-C2H2 PF00096.26 KFP06234.1 - 0.75 10.4 3.9 0.26 11.8 1.0 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type Vma12 PF11712.8 KFP06234.1 - 2.7 8.1 8.1 19 5.3 5.2 2.1 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Presenilin PF01080.17 KFP06234.1 - 3.4 6.3 3.6 3.2 6.4 3.6 1.2 1 0 0 1 1 1 0 Presenilin Vfa1 PF08432.10 KFP06234.1 - 8.3 6.7 23.5 0.17 12.2 14.6 1.9 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 MPS-4 PF17523.2 KFP06235.1 - 4.2 7.6 5.4 55 4.0 0.2 3.4 2 1 1 3 3 3 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 PID PF00640.23 KFP06237.1 - 9.4e-37 126.2 0.0 3.5e-31 108.1 0.0 2.3 2 1 0 2 2 2 2 Phosphotyrosine interaction domain (PTB/PID) WW PF00397.26 KFP06237.1 - 1.3e-06 28.4 4.9 3.1e-06 27.2 4.9 1.7 1 0 0 1 1 1 1 WW domain PTB PF08416.13 KFP06237.1 - 3e-05 24.2 0.0 8.9e-05 22.7 0.0 1.7 2 1 0 2 2 2 1 Phosphotyrosine-binding domain YbjN PF10722.9 KFP06237.1 - 0.13 12.3 0.0 5.5 7.1 0.0 2.3 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator SRA1 PF07304.11 KFP06238.1 - 6.2e-58 194.7 0.1 7.7e-58 194.4 0.1 1.0 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) GUN4 PF05419.12 KFP06238.1 - 0.094 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 GUN4-like Se-cys_synth_N PF12390.8 KFP06238.1 - 0.22 11.8 1.9 16 5.8 0.1 2.9 3 0 0 3 3 3 0 Selenocysteine synthase N terminal eIF_4EBP PF05456.11 KFP06239.1 - 6.4e-17 61.5 0.1 6.7e-17 61.5 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) HCO3_cotransp PF00955.21 KFP06240.1 - 5.6e-216 718.3 0.0 6.8e-216 718.0 0.0 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 KFP06240.1 - 2.3e-66 224.3 0.0 3.6e-66 223.7 0.0 1.3 1 0 0 1 1 1 1 Band 3 cytoplasmic domain Xan_ur_permease PF00860.20 KFP06240.1 - 2.9 6.5 15.5 0.75 8.4 0.5 3.1 3 0 0 3 3 3 0 Permease family EGF PF00008.27 KFP06241.1 - 7.4e-06 26.2 5.0 1.5e-05 25.1 5.0 1.6 1 0 0 1 1 1 1 EGF-like domain Syndecan PF01034.20 KFP06241.1 - 0.22 11.5 0.7 0.34 10.8 0.7 1.3 1 0 0 1 1 1 0 Syndecan domain EGF_2 PF07974.13 KFP06241.1 - 2.9 8.3 8.3 0.61 10.5 4.6 1.9 2 1 0 2 2 2 0 EGF-like domain hEGF PF12661.7 KFP06241.1 - 4.2 8.2 8.0 2 9.2 4.2 2.5 2 1 0 2 2 2 0 Human growth factor-like EGF Prefoldin_2 PF01920.20 KFP06242.1 - 7.8e-20 70.8 13.0 8.6e-20 70.7 13.0 1.0 1 0 0 1 1 1 1 Prefoldin subunit SPECT1 PF18680.1 KFP06242.1 - 0.016 14.9 1.5 0.019 14.6 0.8 1.5 1 1 0 1 1 1 0 Plasmodium host cell traversal SPECT1 Mei5 PF10376.9 KFP06242.1 - 0.036 13.9 5.2 0.043 13.7 5.2 1.2 1 0 0 1 1 1 0 Double-strand recombination repair protein DUF5320 PF17253.2 KFP06242.1 - 0.23 12.6 0.6 0.29 12.2 0.5 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5320) Phage_GP20 PF06810.11 KFP06242.1 - 0.26 11.1 8.5 0.53 10.1 0.8 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 XhlA PF10779.9 KFP06242.1 - 2.9 8.2 8.3 0.96 9.7 2.9 2.1 2 0 0 2 2 2 0 Haemolysin XhlA Neuregulin PF02158.15 KFP06244.1 - 4e-159 529.8 28.4 4.9e-159 529.5 28.4 1.1 1 0 0 1 1 1 1 Neuregulin intracellular region I-set PF07679.16 KFP06244.1 - 8e-18 64.3 0.0 1.6e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP06244.1 - 1.4e-15 57.7 2.4 1.7e-15 57.4 0.0 2.4 3 0 0 3 3 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFP06244.1 - 4.4e-14 52.6 0.2 1.9e-13 50.5 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 KFP06244.1 - 1.1e-12 47.9 0.0 3.8e-12 46.2 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP06244.1 - 0.00019 21.6 2.4 0.0077 16.4 0.1 2.9 2 1 0 2 2 2 1 Immunoglobulin V-set domain Ig_6 PF18452.1 KFP06244.1 - 0.0088 15.6 0.1 0.03 13.9 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain EGF PF00008.27 KFP06244.1 - 0.022 15.1 6.9 0.09 13.1 6.9 2.2 1 0 0 1 1 1 0 EGF-like domain EGF_2 PF07974.13 KFP06244.1 - 0.061 13.7 10.0 0.17 12.3 10.0 1.8 1 0 0 1 1 1 0 EGF-like domain EphA2_TM PF14575.6 KFP06244.1 - 0.15 12.9 0.0 0.4 11.6 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM132D_C PF15706.5 KFP06244.1 - 0.23 11.2 0.7 0.53 10.1 0.7 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Neur_chan_memb PF02932.16 KFP06244.1 - 0.43 10.6 2.6 0.26 11.3 0.6 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Ig_4 PF16680.5 KFP06244.1 - 1.1 9.6 5.7 0.2 11.9 0.4 2.6 2 1 0 2 2 1 0 T-cell surface glycoprotein CD3 delta chain Sec7 PF01369.20 KFP06245.1 - 1e-42 145.9 0.2 2.7e-42 144.5 0.0 1.8 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.6 KFP06245.1 - 6.4e-38 129.8 3.5 8.6e-38 129.4 0.1 2.6 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 KFP06245.1 - 7.8e-14 52.1 0.1 2.2e-13 50.6 0.1 1.8 1 0 0 1 1 1 1 PH domain COBRA1 PF06209.13 KFP06245.1 - 0.0061 15.5 0.5 0.049 12.5 0.0 2.1 2 0 0 2 2 2 1 Cofactor of BRCA1 (COBRA1) PH_11 PF15413.6 KFP06245.1 - 0.021 15.2 0.2 0.1 13.0 0.2 2.2 1 0 0 1 1 1 0 Pleckstrin homology domain NADPH_Ox PF08414.10 KFP06245.1 - 0.086 13.2 0.1 0.23 11.8 0.1 1.7 1 0 0 1 1 1 0 Respiratory burst NADPH oxidase zf-CXXC PF02008.20 KFP06246.1 - 1.8e-07 31.1 23.5 2.8e-07 30.5 23.5 1.3 1 0 0 1 1 1 1 CXXC zinc finger domain TCO89 PF10452.9 KFP06246.1 - 0.073 12.0 4.6 0.11 11.5 4.6 1.1 1 0 0 1 1 1 0 TORC1 subunit TCO89 QueC PF06508.13 KFP06246.1 - 3.6 7.0 11.0 2 7.9 0.8 2.3 1 1 1 2 2 2 0 Queuosine biosynthesis protein QueC zf-RING_2 PF13639.6 KFP06247.1 - 2.7e-12 46.8 6.6 4.7e-12 46.0 6.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFP06247.1 - 3.8e-10 39.3 1.5 9e-10 38.1 1.5 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFP06247.1 - 3.8e-08 33.0 6.4 7e-08 32.2 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP06247.1 - 1.9e-07 30.8 4.7 3.4e-07 30.0 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP06247.1 - 4.4e-07 29.8 3.5 7.4e-07 29.0 3.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP06247.1 - 1.8e-06 27.7 4.4 3.4e-06 26.8 4.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFP06247.1 - 3.4e-06 27.3 8.3 8.9e-06 25.9 8.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain PA PF02225.22 KFP06247.1 - 3.6e-06 26.9 0.1 7.4e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 PA domain zf-C3HC4_3 PF13920.6 KFP06247.1 - 1.4e-05 24.8 3.6 2.4e-05 24.1 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP06247.1 - 1.8e-05 24.6 4.7 3.4e-05 23.8 4.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger PspB PF06667.12 KFP06247.1 - 0.002 18.1 0.2 0.0034 17.4 0.2 1.3 1 0 0 1 1 1 1 Phage shock protein B Ninjurin PF04923.12 KFP06247.1 - 0.0022 17.9 0.3 0.0047 16.8 0.3 1.5 1 0 0 1 1 1 1 Ninjurin CrgA PF06781.12 KFP06247.1 - 0.003 17.6 0.2 0.0065 16.5 0.2 1.6 1 0 0 1 1 1 1 Cell division protein CrgA zf-ANAPC11 PF12861.7 KFP06247.1 - 0.0098 15.9 2.3 0.019 15.0 2.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger BatD PF13584.6 KFP06247.1 - 0.028 13.2 0.1 0.042 12.7 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance zf-C3H2C3 PF17122.5 KFP06247.1 - 0.052 13.6 2.7 0.12 12.4 2.7 1.6 1 0 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 KFP06247.1 - 0.081 12.6 5.2 0.43 10.2 5.6 1.9 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type Pox_A31 PF05771.11 KFP06247.1 - 0.12 12.3 0.2 0.2 11.7 0.2 1.3 1 0 0 1 1 1 0 Poxvirus A31 protein PHD PF00628.29 KFP06247.1 - 0.22 11.5 4.3 0.42 10.5 4.3 1.5 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 KFP06247.1 - 0.56 10.4 4.4 1.2 9.4 4.4 1.5 1 0 0 1 1 1 0 RING-variant domain NOA36 PF06524.12 KFP06249.1 - 4.1e-165 548.5 43.8 4.9e-165 548.3 43.8 1.0 1 0 0 1 1 1 1 NOA36 protein IL15 PF02372.15 KFP06250.1 - 1e-40 138.9 10.9 1.2e-40 138.6 10.9 1.0 1 0 0 1 1 1 1 Interleukin 15 UCH PF00443.29 KFP06252.1 - 5.1e-41 140.9 0.4 7.9e-41 140.2 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP06252.1 - 2.4e-20 73.4 5.0 2.1e-19 70.3 5.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PH PF00169.29 KFP06253.1 - 1.1e-18 67.7 4.2 1.3e-18 67.4 0.1 3.0 4 0 0 4 4 4 1 PH domain PH_11 PF15413.6 KFP06253.1 - 2e-05 25.0 0.3 0.00012 22.5 0.3 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 KFP06253.1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain PH_3 PF14593.6 KFP06253.1 - 0.11 12.6 0.3 0.31 11.2 0.3 1.7 1 1 0 1 1 1 0 PH domain PH_2 PF08458.10 KFP06253.1 - 0.23 11.8 0.0 0.44 10.9 0.0 1.4 1 0 0 1 1 1 0 Plant pleckstrin homology-like region SNF2_N PF00176.23 KFP06254.1 - 9.6e-80 267.9 0.9 1.8e-79 267.0 0.2 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.10 KFP06254.1 - 4.5e-42 142.7 2.3 1.6e-41 140.9 2.3 2.1 1 0 0 1 1 1 1 SLIDE HAND PF09110.11 KFP06254.1 - 2.5e-31 108.7 2.1 2.5e-31 108.7 2.1 3.5 4 0 0 4 4 4 1 HAND Helicase_C PF00271.31 KFP06254.1 - 3.4e-20 72.4 0.0 2.9e-19 69.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP06254.1 - 1.6e-11 44.5 0.0 1.3e-10 41.6 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFP06254.1 - 8.7e-07 28.9 0.0 3.2e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 KFP06254.1 - 8.1e-05 22.7 0.3 0.37 11.0 0.0 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain HDA2-3 PF11496.8 KFP06254.1 - 0.00012 21.3 0.0 0.00029 20.1 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DBINO PF13892.6 KFP06254.1 - 0.0013 19.1 0.6 0.0013 19.1 0.6 4.0 5 0 0 5 5 5 1 DNA-binding domain GSDH PF07995.11 KFP06255.1 - 3.4e-19 69.3 0.0 5.1e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase EGF_2 PF07974.13 KFP06255.1 - 0.00043 20.6 10.2 0.00043 20.6 10.2 3.3 2 1 1 3 3 3 2 EGF-like domain ANAPC10 PF03256.16 KFP06256.1 - 4.2e-83 277.5 0.0 5e-83 277.3 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 KFP06256.1 - 4.5e-05 23.6 0.0 5.9e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain PITH PF06201.13 KFP06256.1 - 0.0018 18.5 0.1 0.011 15.9 0.1 1.9 1 1 1 2 2 2 1 PITH domain ABC_tran PF00005.27 KFP06257.1 - 7.4e-38 130.2 0.0 1.5e-18 67.6 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 KFP06257.1 - 1.5e-14 53.5 7.2 4.2e-14 52.1 7.2 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 KFP06257.1 - 4.2e-11 42.7 1.6 0.0021 17.5 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFP06257.1 - 9.5e-11 42.0 2.9 0.17 11.7 0.7 4.4 3 2 0 5 5 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 KFP06257.1 - 8.6e-07 28.5 1.7 8.6e-07 28.5 1.7 3.5 4 0 0 4 4 3 1 4Fe-4S binding domain AAA_16 PF13191.6 KFP06257.1 - 1.1e-05 25.8 0.0 0.027 14.8 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 KFP06257.1 - 1.5e-05 24.9 0.0 0.22 11.2 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 KFP06257.1 - 3.1e-05 24.4 0.0 0.05 14.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KFP06257.1 - 3.9e-05 23.6 0.0 0.14 12.0 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KFP06257.1 - 4.9e-05 23.6 0.0 0.011 16.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFP06257.1 - 9.3e-05 22.1 0.4 0.54 10.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4_6 PF12837.7 KFP06257.1 - 0.00015 21.6 1.3 0.00015 21.6 1.3 3.2 3 0 0 3 3 2 1 4Fe-4S binding domain NACHT PF05729.12 KFP06257.1 - 0.00053 19.9 0.4 0.091 12.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Fer4_7 PF12838.7 KFP06257.1 - 0.00083 19.9 7.4 0.01 16.4 1.2 3.2 3 1 0 3 3 3 1 4Fe-4S dicluster domain Rad17 PF03215.15 KFP06257.1 - 0.0013 18.7 0.0 0.67 9.8 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_30 PF13604.6 KFP06257.1 - 0.0016 18.2 0.2 0.079 12.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KFP06257.1 - 0.0019 18.7 2.7 0.061 13.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFP06257.1 - 0.0022 18.2 0.0 0.49 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KFP06257.1 - 0.0022 17.8 0.2 0.57 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFP06257.1 - 0.0024 18.2 0.0 2.1 8.8 0.0 3.4 3 0 0 3 3 3 1 RNA helicase SRP54 PF00448.22 KFP06257.1 - 0.003 17.2 1.9 0.31 10.6 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_2 PF12797.7 KFP06257.1 - 0.0031 17.5 0.7 0.0031 17.5 0.7 2.8 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_28 PF13521.6 KFP06257.1 - 0.011 16.0 0.2 4.4 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_10 PF13237.6 KFP06257.1 - 0.011 15.8 2.0 0.011 15.8 2.0 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain TsaE PF02367.17 KFP06257.1 - 0.014 15.4 0.2 0.23 11.5 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_21 PF14697.6 KFP06257.1 - 0.021 14.9 14.0 0.053 13.7 13.3 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 KFP06257.1 - 0.021 14.9 10.8 0.021 14.9 10.8 1.9 2 0 0 2 2 1 0 4Fe-4S dicluster domain AAA_18 PF13238.6 KFP06257.1 - 0.041 14.4 0.0 9.1 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Fer4_16 PF13484.6 KFP06257.1 - 0.045 14.7 1.0 0.045 14.7 1.0 2.9 3 0 0 3 3 2 0 4Fe-4S double cluster binding domain Septin PF00735.18 KFP06257.1 - 0.078 12.2 0.1 4 6.6 0.0 2.6 3 0 0 3 3 3 0 Septin AAA_5 PF07728.14 KFP06257.1 - 0.083 12.9 1.1 1.2 9.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 KFP06257.1 - 0.085 12.9 0.7 19 5.4 0.0 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.22 KFP06257.1 - 0.089 12.0 0.0 6.9 5.8 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain VirE PF05272.11 KFP06257.1 - 0.1 12.3 0.0 5.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E AAA_7 PF12775.7 KFP06257.1 - 0.12 11.9 0.2 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region MeaB PF03308.16 KFP06257.1 - 0.13 11.2 0.1 8 5.4 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 KFP06257.1 - 0.16 11.8 0.1 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SbcCD_C PF13558.6 KFP06257.1 - 0.2 11.9 0.1 14 6.0 0.0 3.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 KFP06257.1 - 0.39 10.8 3.1 29 4.7 0.0 3.6 3 1 1 4 4 3 0 AAA domain Fer4_17 PF13534.6 KFP06257.1 - 1.9 9.1 9.7 0.12 12.9 0.8 2.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 KFP06257.1 - 4.6 8.0 14.0 0.45 11.1 1.4 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain OTU PF02338.19 KFP06258.1 - 6.9e-14 52.4 0.0 1.5e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease SMN PF06003.12 KFP06258.1 - 0.0021 17.3 0.0 0.0021 17.3 0.0 3.9 5 0 0 5 5 5 1 Survival motor neuron protein (SMN) Peptidase_C65 PF10275.9 KFP06258.1 - 0.047 13.1 0.7 9.9 5.5 0.0 2.5 1 1 1 2 2 2 0 Peptidase C65 Otubain MH2 PF03166.14 KFP06259.1 - 5.4e-45 153.9 0.7 9e-45 153.2 0.7 1.3 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 KFP06259.1 - 2.5e-42 143.3 1.2 5.3e-42 142.2 1.2 1.6 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.9 KFP06259.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Interferon-regulatory factor 3 DUF4223 PF13978.6 KFP06259.1 - 0.13 12.3 0.8 0.24 11.4 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) MeaB PF03308.16 KFP06260.1 - 3.3e-96 321.4 0.2 4.3e-96 321.0 0.2 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KFP06260.1 - 2.4e-05 24.6 1.0 0.00053 20.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 KFP06260.1 - 0.00016 21.3 0.0 0.0014 18.3 0.0 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 KFP06260.1 - 0.0003 20.6 0.0 0.00075 19.3 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 KFP06260.1 - 0.0053 17.3 0.0 0.017 15.6 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_30 PF13604.6 KFP06260.1 - 0.0093 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KFP06260.1 - 0.015 15.8 0.1 0.034 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KFP06260.1 - 0.017 15.2 0.0 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase MnmE_helical PF12631.7 KFP06260.1 - 0.028 14.6 0.0 0.046 13.9 0.0 1.3 1 1 0 1 1 1 0 MnmE helical domain AAA_16 PF13191.6 KFP06260.1 - 0.045 14.1 0.1 0.14 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain Thymidylate_kin PF02223.17 KFP06260.1 - 0.063 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase NTPase_1 PF03266.15 KFP06260.1 - 0.078 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 NTPase Mg_chelatase PF01078.21 KFP06260.1 - 0.078 12.3 0.1 0.53 9.6 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 KFP06260.1 - 0.088 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KFP06260.1 - 0.089 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFP06260.1 - 0.097 12.8 0.2 0.38 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KFP06260.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain AAA_18 PF13238.6 KFP06260.1 - 0.13 12.8 0.1 0.43 11.1 0.1 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFP06260.1 - 0.21 12.0 0.0 0.73 10.3 0.0 1.9 2 0 0 2 2 2 0 RNA helicase zf-C2H2 PF00096.26 KFP06261.1 - 4.7e-16 58.2 76.9 0.00038 20.8 0.2 9.4 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFP06261.1 - 8.3e-14 51.0 54.1 0.00056 19.6 3.1 7.5 7 0 0 7 7 7 5 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KFP06261.1 - 8.2e-10 38.7 75.6 0.00057 20.2 4.7 11.3 11 1 0 11 11 11 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP06261.1 - 1.8e-08 34.5 77.0 0.0026 18.5 0.3 9.6 9 0 0 9 9 9 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFP06261.1 - 0.0013 18.7 0.2 0.0013 18.7 0.2 6.3 8 1 0 8 8 7 2 C2H2-type zinc finger zf-met PF12874.7 KFP06261.1 - 0.0024 18.2 61.8 0.8 10.2 2.8 9.1 9 0 0 9 9 8 6 Zinc-finger of C2H2 type zf-MYST PF17772.1 KFP06261.1 - 0.015 14.9 5.2 0.82 9.3 1.3 3.2 2 1 1 3 3 3 0 MYST family zinc finger domain SRP54_N PF02881.19 KFP06261.1 - 0.04 14.1 3.6 5.5 7.3 0.0 3.4 3 0 0 3 3 3 0 SRP54-type protein, helical bundle domain zf-C2H2_jaz PF12171.8 KFP06261.1 - 0.63 10.4 0.0 0.054 13.8 0.9 7.9 8 0 0 8 8 7 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFP06261.1 - 0.98 9.3 0.0 0.98 9.3 0.0 4.8 5 0 0 5 5 5 0 GAGA factor DUF899 PF05988.12 KFP06261.1 - 2.7 7.4 9.4 0.081 12.4 0.5 2.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF899) zf-C2H2_7 PF15269.6 KFP06261.1 - 7.7 6.7 44.3 0.17 12.0 1.2 7.5 5 2 3 8 8 8 0 Zinc-finger LSM PF01423.22 KFP06262.1 - 8.3e-20 70.3 0.1 9.4e-20 70.1 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFP06262.1 - 4.1e-05 23.6 0.0 4.8e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KFP06262.1 - 0.027 14.6 0.1 0.029 14.4 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain Reeler PF02014.16 KFP06263.1 - 4.1e-30 105.2 0.0 4.8e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 Reeler domain DUF4320 PF14208.6 KFP06263.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) SBF_like PF13593.6 KFP06264.1 - 4.1e-73 246.4 21.2 4.6e-73 246.3 21.2 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 KFP06264.1 - 2.6e-16 59.9 12.5 2.6e-16 59.9 12.5 2.1 2 1 0 2 2 2 1 Sodium Bile acid symporter family Phtf-FEM1B_bdg PF12129.8 KFP06264.1 - 0.89 9.4 6.3 0.64 9.8 0.3 2.6 2 1 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor Oxidored_q4 PF00507.19 KFP06264.1 - 3 8.1 8.9 0.21 11.7 2.5 2.4 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF373 PF04123.13 KFP06264.1 - 8.6 5.7 8.3 1.1e+02 2.0 8.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Pou PF00157.17 KFP06265.1 - 2.4e-31 107.5 0.1 5.2e-31 106.4 0.1 1.6 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KFP06265.1 - 5e-18 64.7 1.9 1.3e-17 63.4 1.9 1.7 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 KFP06265.1 - 0.00011 22.5 0.0 0.011 16.1 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain Homeobox_KN PF05920.11 KFP06265.1 - 0.032 14.1 0.1 0.072 13.0 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain DUF4770 PF15994.5 KFP06265.1 - 0.08 13.2 0.9 0.098 12.9 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) HTH_19 PF12844.7 KFP06265.1 - 0.093 12.8 0.0 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain TPR_12 PF13424.6 KFP06266.1 - 4.1e-11 43.0 13.5 0.0032 17.7 0.0 5.2 4 1 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFP06266.1 - 1.2e-07 31.3 1.6 0.0081 16.1 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFP06266.1 - 3.3e-07 29.9 10.5 0.39 10.9 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFP06266.1 - 1.4e-06 27.9 9.2 0.036 13.9 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP06266.1 - 0.00015 21.2 7.7 0.0016 17.9 0.4 2.7 1 1 1 2 2 2 2 MalT-like TPR region TPR_10 PF13374.6 KFP06266.1 - 0.00022 21.0 0.5 0.52 10.2 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP06266.1 - 0.00031 20.7 9.2 0.092 13.0 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFP06266.1 - 0.016 14.9 4.8 0.16 11.7 0.2 3.8 4 0 0 4 4 4 0 TPR repeat TPR_19 PF14559.6 KFP06266.1 - 0.024 15.1 3.2 0.13 12.7 0.1 3.1 3 1 0 3 3 2 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KFP06266.1 - 0.032 13.7 0.1 1.6 8.2 0.0 2.9 2 0 0 2 2 2 0 SHNi-TPR TPR_14 PF13428.6 KFP06266.1 - 0.04 14.8 4.5 8.5 7.5 0.0 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat Cation_ATPase_N PF00690.26 KFP06266.1 - 0.15 11.8 0.4 5.2 6.8 0.0 2.8 3 0 0 3 3 3 0 Cation transporter/ATPase, N-terminus TPR_4 PF07721.14 KFP06266.1 - 0.21 12.3 3.0 66 4.6 0.4 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat MAS20 PF02064.15 KFP06266.1 - 0.81 9.8 4.4 3.5 7.7 0.1 3.1 2 1 2 4 4 4 0 MAS20 protein import receptor TPR_6 PF13174.6 KFP06266.1 - 1.5 9.6 7.9 1.4e+02 3.4 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat 7tm_1 PF00001.21 KFP06268.1 - 3.6e-35 121.6 9.0 3.6e-35 121.6 9.0 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP06268.1 - 0.0029 17.0 14.0 0.15 11.4 12.7 3.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP06268.1 - 0.012 15.4 3.0 0.018 14.8 3.0 1.6 1 1 0 1 1 1 0 Olfactory receptor Solute_trans_a PF03619.16 KFP06269.1 - 3.4e-101 338.2 19.2 4.1e-101 338.0 19.2 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha zf-C4 PF00105.18 KFP06270.1 - 1.6e-28 99.0 13.0 2.8e-28 98.2 13.0 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFP06270.1 - 1.1e-13 51.3 0.1 1.7e-13 50.7 0.1 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Lipase_GDSL_2 PF13472.6 KFP06271.1 - 0.00015 22.2 0.0 0.00031 21.2 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family NAPRTase_N PF17767.1 KFP06271.1 - 0.18 12.2 0.0 0.28 11.6 0.0 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DUF1192 PF06698.11 KFP06271.1 - 0.26 11.4 1.5 0.71 10.0 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Pkinase PF00069.25 KFP06272.1 - 9.7e-74 248.1 0.0 1.5e-73 247.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DCX PF03607.17 KFP06272.1 - 1.5e-43 146.7 0.1 5.7e-23 80.8 0.0 2.6 2 0 0 2 2 2 2 Doublecortin Pkinase_Tyr PF07714.17 KFP06272.1 - 4.4e-33 114.7 0.0 6.7e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP06272.1 - 0.0016 17.9 0.0 0.0049 16.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFP06272.1 - 0.0038 16.6 0.0 0.0065 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFP06272.1 - 0.045 12.5 0.1 0.11 11.2 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Mab-21 PF03281.14 KFP06273.1 - 5.3e-100 334.5 0.0 6.4e-100 334.2 0.0 1.1 1 0 0 1 1 1 1 Mab-21 protein Beach PF02138.18 KFP06274.1 - 3.4e-126 420.2 0.1 5.7e-126 419.5 0.1 1.3 1 0 0 1 1 1 1 Beige/BEACH domain FYVE PF01363.21 KFP06274.1 - 7e-16 58.1 9.8 1.7e-15 56.9 9.8 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH_BEACH PF14844.6 KFP06274.1 - 1e-12 48.0 0.0 2.9e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 KFP06274.1 - 9.7e-07 29.4 9.3 0.0038 18.0 0.2 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF4704 PF15787.5 KFP06274.1 - 1.8e-06 27.4 3.6 3.6e-06 26.4 0.8 2.9 2 1 1 3 3 3 2 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 KFP06274.1 - 0.0016 18.6 0.0 0.0049 17.0 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4800 PF16057.5 KFP06274.1 - 0.0062 15.8 1.4 0.014 14.6 1.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) E3_UbLigase_R4 PF13764.6 KFP06274.1 - 0.054 11.7 0.2 0.13 10.4 0.2 1.5 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 RVT_1 PF00078.27 KFP06275.1 - 0.13 11.8 0.0 0.32 10.5 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) CTP_transf_1 PF01148.20 KFP06276.1 - 1.8e-85 286.9 20.6 2.2e-85 286.6 20.6 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF373 PF04123.13 KFP06276.1 - 7.8 5.8 9.0 13 5.1 9.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Acyltransferase PF01553.21 KFP06278.1 - 1.2e-19 70.2 0.1 2.7e-19 69.1 0.1 1.6 1 0 0 1 1 1 1 Acyltransferase RlmM_FDX PF18125.1 KFP06278.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 RlmM ferredoxin-like domain Acyltransferase PF01553.21 KFP06279.1 - 1.9e-11 43.7 0.0 3e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Tropomyosin PF00261.20 KFP06280.1 - 0.00024 20.6 0.8 0.00024 20.6 0.8 2.1 2 0 0 2 2 2 1 Tropomyosin DUF2096 PF09869.9 KFP06280.1 - 0.024 14.7 1.4 0.038 14.1 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) Cdh1_DBD_1 PF18196.1 KFP06280.1 - 1.7 9.0 6.3 0.13 12.6 0.8 1.9 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 Ribosomal_S18 PF01084.20 KFP06281.1 - 1.3e-23 82.9 1.0 3.7e-23 81.5 0.0 2.0 3 0 0 3 3 3 1 Ribosomal protein S18 Vps36-NZF-N PF16988.5 KFP06281.1 - 0.024 14.0 0.1 0.042 13.2 0.1 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Glyco_hydro_79n PF03662.14 KFP06282.1 - 1e-26 93.6 0.1 4.6e-26 91.5 0.3 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 79, N-terminal domain UbiA PF01040.18 KFP06283.1 - 8.3e-53 179.3 8.2 9.7e-53 179.0 8.2 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF4018 PF13210.6 KFP06283.1 - 0.0013 18.5 0.4 0.0038 17.0 0.0 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4018) PLAC8 PF04749.17 KFP06284.1 - 7.7e-11 42.9 18.6 1.5e-10 42.0 18.6 1.5 1 1 0 1 1 1 1 PLAC8 family ABC2_membrane PF01061.24 KFP06285.1 - 3e-34 118.3 23.0 3e-34 118.3 23.0 1.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KFP06285.1 - 4.6e-22 79.0 0.1 1e-21 77.9 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KFP06285.1 - 3.4e-07 30.4 0.0 0.0025 17.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFP06285.1 - 3.8e-05 23.2 0.1 0.044 13.2 0.1 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFP06285.1 - 0.00016 22.2 0.8 0.0004 20.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFP06285.1 - 0.0037 17.0 0.1 0.0084 15.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_2 PF12679.7 KFP06285.1 - 0.053 12.8 16.9 0.035 13.4 12.3 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF87 PF01935.17 KFP06285.1 - 0.23 11.5 1.0 0.54 10.3 0.0 2.0 3 0 0 3 3 3 0 Helicase HerA, central domain ABC2_membrane_3 PF12698.7 KFP06285.1 - 0.77 8.8 30.0 2.3 7.3 30.0 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein PKD_channel PF08016.12 KFP06286.1 - 1e-160 535.1 19.1 1.2e-160 534.9 19.1 1.0 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KFP06286.1 - 2.3e-24 86.0 28.9 3.9e-24 85.2 28.9 1.4 1 0 0 1 1 1 1 Ion transport protein EF-hand_1 PF00036.32 KFP06286.1 - 0.00019 20.7 1.2 0.015 14.8 0.3 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KFP06286.1 - 0.0034 17.2 0.7 0.049 13.6 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain DUF21 PF01595.20 KFP06286.1 - 0.016 14.9 2.5 0.078 12.7 0.1 2.6 2 1 0 2 2 2 0 Cyclin M transmembrane N-terminal domain EF-hand_8 PF13833.6 KFP06286.1 - 0.11 12.4 0.4 0.32 10.9 0.4 1.9 1 0 0 1 1 1 0 EF-hand domain pair Osteopontin PF00865.18 KFP06287.1 - 2.8e-16 59.8 11.5 1.3e-14 54.4 11.2 2.3 1 1 0 1 1 1 1 Osteopontin SURF2 PF05477.11 KFP06287.1 - 0.0056 16.4 0.8 0.0068 16.1 0.8 1.2 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) DMP1 PF07263.11 KFP06287.1 - 0.04 12.8 11.7 0.47 9.3 0.0 2.1 1 1 1 2 2 2 0 Dentin matrix protein 1 (DMP1) FAM76 PF16046.5 KFP06287.1 - 0.096 12.0 0.4 0.12 11.7 0.4 1.1 1 0 0 1 1 1 0 FAM76 protein BSP_II PF05432.11 KFP06289.1 - 1.5e-61 208.8 64.8 2.8e-35 122.5 54.3 2.1 2 0 0 2 2 2 2 Bone sialoprotein II (BSP-II) BAT2_N PF07001.11 KFP06289.1 - 0.0077 16.7 6.4 0.0077 16.7 6.4 2.3 1 1 1 2 2 2 1 BAT2 N-terminus SAPS PF04499.15 KFP06289.1 - 0.019 13.8 12.1 0.021 13.6 12.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein UPF0564 PF10595.9 KFP06289.1 - 0.035 13.2 11.1 0.049 12.7 11.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 Drc1-Sld2 PF11719.8 KFP06289.1 - 0.063 12.8 11.0 0.088 12.3 11.0 1.4 1 0 0 1 1 1 0 DNA replication and checkpoint protein SLC12 PF03522.15 KFP06289.1 - 0.17 10.9 6.3 0.24 10.4 6.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF1387 PF07139.11 KFP06289.1 - 0.45 10.2 14.1 0.62 9.7 14.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) rRNA_processing PF08524.11 KFP06289.1 - 1.2 9.2 17.7 2.4 8.2 17.7 1.5 1 0 0 1 1 1 0 rRNA processing LAP1C PF05609.12 KFP06289.1 - 1.7 7.6 13.9 2.5 7.1 13.9 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PA26 PF04636.13 KFP06289.1 - 2.2 7.1 7.9 3.1 6.6 7.9 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Hid1 PF12722.7 KFP06289.1 - 2.2 6.3 10.0 2.8 6.0 10.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC27 PF09507.10 KFP06289.1 - 2.7 7.3 20.4 4.8 6.5 20.4 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 WRNPLPNID PF15017.6 KFP06289.1 - 3.2 8.7 36.2 0.61 11.0 8.2 3.7 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box Presenilin PF01080.17 KFP06289.1 - 3.6 6.3 15.5 5.7 5.6 15.5 1.3 1 0 0 1 1 1 0 Presenilin Menin PF05053.13 KFP06289.1 - 4 5.7 7.8 5.6 5.2 7.8 1.3 1 0 0 1 1 1 0 Menin SDA1 PF05285.12 KFP06289.1 - 6.5 6.1 37.8 2.1 7.7 34.6 1.7 2 0 0 2 2 2 0 SDA1 Apt1 PF10351.9 KFP06289.1 - 8.8 5.0 7.7 13 4.5 7.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain DMP1 PF07263.11 KFP06290.1 - 3.7e-10 39.3 40.6 4.4e-10 39.1 40.6 1.1 1 0 0 1 1 1 1 Dentin matrix protein 1 (DMP1) SPARC_Ca_bdg PF10591.9 KFP06291.1 - 3.6e-39 133.6 0.7 6.3e-39 132.8 0.7 1.4 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_1 PF00050.21 KFP06291.1 - 1.2e-14 54.1 6.4 4.1e-14 52.3 6.4 1.9 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain FOLN PF09289.10 KFP06291.1 - 6.8e-10 38.9 9.7 6.8e-10 38.9 9.7 2.4 2 0 0 2 2 2 1 Follistatin/Osteonectin-like EGF domain Kazal_2 PF07648.15 KFP06291.1 - 1.7e-09 37.6 2.5 1.7e-09 37.6 2.5 2.8 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.6 KFP06291.1 - 0.029 14.8 1.5 2.7 8.5 0.1 2.7 2 1 0 2 2 2 0 EF-hand domain pair NUDIX PF00293.28 KFP06292.1 - 1.3e-09 38.2 1.1 3.2e-09 36.9 1.1 1.7 1 1 0 1 1 1 1 NUDIX domain L27 PF02828.16 KFP06292.1 - 0.089 12.6 0.2 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 L27 domain Bcl-2 PF00452.19 KFP06293.1 - 1e-22 80.7 0.1 2.1e-22 79.7 0.1 1.6 2 0 0 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family TetR_C_20 PF17925.1 KFP06293.1 - 0.077 13.3 0.1 0.14 12.5 0.1 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Pkinase PF00069.25 KFP06294.1 - 1e-70 238.1 0.0 1.3e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP06294.1 - 1.9e-52 178.1 0.0 3e-52 177.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP06294.1 - 1.8e-05 23.7 0.0 3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF1241 PF06840.11 KFP06294.1 - 6.5e-05 22.6 0.0 0.00016 21.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Kinase-like PF14531.6 KFP06294.1 - 0.0032 16.8 0.1 0.02 14.2 0.0 2.1 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFP06294.1 - 0.016 14.2 0.0 0.58 9.1 0.0 2.1 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KFP06294.1 - 0.03 14.3 0.0 0.47 10.3 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family RhoGEF PF00621.20 KFP06295.1 - 1.1e-36 126.8 3.2 3.1e-36 125.3 3.2 1.8 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 KFP06295.1 - 7.9e-26 90.6 0.7 6.1e-14 52.4 0.3 2.7 2 0 0 2 2 2 2 PH domain FERM_C PF09380.10 KFP06295.1 - 4.8e-25 87.8 0.1 1.3e-24 86.4 0.1 1.8 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KFP06295.1 - 2.7e-14 52.8 0.1 7.9e-14 51.4 0.1 1.9 1 0 0 1 1 1 1 FERM N-terminal domain FA PF08736.11 KFP06295.1 - 3.6e-12 46.2 1.3 9.2e-12 44.8 1.3 1.7 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_M PF00373.18 KFP06295.1 - 1e-08 35.6 0.2 3.2e-08 34.0 0.2 1.9 1 0 0 1 1 1 1 FERM central domain IQ_SEC7_PH PF16453.5 KFP06295.1 - 1.5e-06 28.3 0.1 1e-05 25.5 0.0 2.3 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 KFP06295.1 - 0.00043 20.1 3.4 0.3 10.9 0.0 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 KFP06295.1 - 0.037 14.4 3.8 2.9 8.3 1.4 3.4 3 1 0 3 3 3 0 Pleckstrin homology domain PH_11 PF15413.6 KFP06295.1 - 1.7 9.1 9.9 2 8.9 2.4 3.9 3 1 0 3 3 3 0 Pleckstrin homology domain Septin PF00735.18 KFP06296.1 - 2.4e-129 430.6 0.1 3.1e-129 430.2 0.1 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFP06296.1 - 3.1e-08 33.7 0.1 1.2e-07 31.8 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP06296.1 - 7.9e-06 25.5 1.2 0.0042 16.7 0.0 2.6 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFP06296.1 - 2.6e-05 24.2 3.9 0.0014 18.6 0.3 2.9 3 1 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 KFP06296.1 - 0.00021 20.7 0.8 0.00045 19.6 0.0 1.9 2 0 0 2 2 2 1 AIG1 family Ras PF00071.22 KFP06296.1 - 0.00058 19.5 0.0 0.0013 18.3 0.0 1.7 1 0 0 1 1 1 1 Ras family Dynamin_N PF00350.23 KFP06296.1 - 0.00069 19.7 1.5 0.085 12.9 0.0 3.1 2 1 1 3 3 3 1 Dynamin family AAA_22 PF13401.6 KFP06296.1 - 0.0031 17.8 0.9 0.019 15.3 0.1 2.7 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 KFP06296.1 - 0.0045 17.2 0.0 0.009 16.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KFP06296.1 - 0.0051 17.2 0.1 0.019 15.3 0.0 2.1 3 0 0 3 3 3 1 AAA ATPase domain Gtr1_RagA PF04670.12 KFP06296.1 - 0.012 14.9 0.3 0.39 10.0 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 KFP06296.1 - 0.015 15.8 1.2 0.025 15.1 0.1 1.9 2 1 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 KFP06296.1 - 0.021 14.6 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KFP06296.1 - 0.039 13.5 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RGS_DHEX PF18148.1 KFP06296.1 - 0.35 11.0 3.2 6.6 6.9 0.7 2.6 2 1 0 2 2 2 0 Regulator of G-protein signalling DHEX domain AAA_28 PF13521.6 KFP06296.1 - 0.92 9.7 3.7 23 5.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain KH_1 PF00013.29 KFP06297.1 - 1.9e-194 629.8 60.3 4.3e-16 58.5 0.6 15.8 15 1 0 15 15 15 15 KH domain SLS PF14611.6 KFP06297.1 - 8.7e-21 74.8 22.4 9.9e-05 22.3 1.8 9.3 2 2 8 10 10 10 6 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 KFP06297.1 - 2.2e-16 59.4 49.7 0.015 15.1 2.0 12.5 11 2 1 13 13 13 8 KH domain KH_5 PF13184.6 KFP06297.1 - 5.1e-08 32.9 28.9 1.6 8.9 0.3 11.2 11 1 1 12 12 12 4 NusA-like KH domain DUF4530 PF15039.6 KFP06297.1 - 0.0014 18.8 0.1 1.8 8.7 0.0 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4530) BMC PF00936.19 KFP06297.1 - 0.0039 17.2 4.3 55 3.8 0.1 7.4 10 0 0 10 10 10 0 BMC domain Lactamase_B_4 PF13691.6 KFP06297.1 - 0.015 15.0 0.0 21 4.9 0.0 4.0 3 0 0 3 3 3 0 tRNase Z endonuclease SCO1-SenC PF02630.14 KFP06297.1 - 0.019 14.9 8.2 9.7 6.1 0.0 8.0 11 0 0 11 11 11 0 SCO1/SenC DUF2096 PF09869.9 KFP06297.1 - 0.059 13.5 20.1 2.5 8.1 0.4 7.5 9 1 0 10 10 10 0 Uncharacterized protein conserved in archaea (DUF2096) KH_4 PF13083.6 KFP06297.1 - 0.72 9.8 28.0 1.3 9.0 0.0 10.1 9 2 3 12 12 12 0 KH domain DUF531 PF04407.12 KFP06297.1 - 4.7 7.3 8.2 22 5.1 0.1 5.1 4 2 2 6 6 6 0 Protein of unknown function (DUF531) FtsQ PF03799.15 KFP06297.1 - 6.5 7.6 6.9 5.2e+02 1.5 0.1 6.1 4 2 5 9 9 9 0 Cell division protein FtsQ LRR_4 PF12799.7 KFP06298.1 - 2.8e-37 126.1 41.3 2e-09 37.5 2.1 7.2 3 2 2 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP06298.1 - 1.3e-23 82.5 38.6 9.5e-08 31.7 6.3 6.3 2 2 3 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 KFP06298.1 - 1.2e-22 80.2 36.0 2.6e-08 33.6 8.2 4.0 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 KFP06298.1 - 0.0043 17.0 26.1 2.1 8.6 0.0 8.0 8 1 1 9 9 9 3 Leucine Rich repeat Ribosomal_L50 PF10501.9 KFP06298.1 - 0.02 15.1 3.7 9.2 6.5 0.1 3.7 1 1 2 4 4 4 0 Ribosomal subunit 39S LRR_1 PF00560.33 KFP06298.1 - 0.03 14.8 32.5 2.1 9.2 0.3 9.1 8 1 0 8 8 8 0 Leucine Rich Repeat UB2H PF14814.6 KFP06298.1 - 0.12 12.5 9.9 28 4.8 0.1 5.5 2 2 5 7 7 7 0 Bifunctional transglycosylase second domain DUF1773 PF08593.10 KFP06298.1 - 0.68 11.0 13.9 25 6.0 0.0 6.1 5 2 1 6 6 6 0 Domain of unknown function CPSase_L_D3 PF02787.19 KFP06298.1 - 1.8 8.9 4.5 1.2e+02 3.0 0.2 3.4 2 1 2 4 4 4 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain RNA_pol_Rpb1_5 PF04998.17 KFP06298.1 - 6.5 6.1 5.4 13 5.1 5.3 1.5 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Mab-21 PF03281.14 KFP06299.1 - 1.6e-18 67.1 0.0 2.3e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein PP2C PF00481.21 KFP06300.1 - 5.6e-63 213.0 0.2 6.7e-63 212.7 0.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFP06300.1 - 0.00011 21.9 0.0 0.00021 21.0 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C C1q PF00386.21 KFP06301.1 - 0.0016 18.6 0.1 0.004 17.4 0.1 1.7 1 1 0 1 1 1 1 C1q domain DUF5522 PF17653.1 KFP06301.1 - 0.28 11.2 1.4 4.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5522) BACK PF07707.15 KFP06302.1 - 1.2e-28 99.2 0.4 2.7e-28 98.1 0.2 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 KFP06302.1 - 5.9e-27 94.1 0.0 9.9e-27 93.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.25 KFP06302.1 - 1.5e-19 69.3 29.4 1.1e-07 31.4 0.1 8.6 8 1 0 8 8 8 5 Kelch motif Kelch_6 PF13964.6 KFP06302.1 - 7.3e-17 61.0 14.0 0.00045 20.4 0.0 7.0 4 2 2 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KFP06302.1 - 8.9e-13 47.7 6.6 0.34 11.0 0.0 6.7 7 0 0 7 7 7 5 Kelch motif Kelch_4 PF13418.6 KFP06302.1 - 2.3e-09 37.1 9.2 0.00044 20.2 0.0 5.8 5 2 1 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP06302.1 - 3.8e-09 36.6 5.8 3.7e-05 23.9 0.8 4.9 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP06302.1 - 1.8e-08 34.2 3.0 0.031 14.2 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Git3 PF11710.8 KFP06302.1 - 0.2 11.4 0.4 2.2 8.0 0.1 2.2 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 ETS_PEA3_N PF04621.13 KFP06303.1 - 2.4e-151 504.5 13.1 3e-151 504.2 13.1 1.1 1 0 0 1 1 1 1 PEA3 subfamily ETS-domain transcription factor N terminal domain Ets PF00178.22 KFP06303.1 - 2.1e-35 121.0 0.1 3.2e-35 120.4 0.1 1.3 1 0 0 1 1 1 1 Ets-domain DAGK_acc PF00609.19 KFP06304.1 - 6.2e-56 189.1 0.0 9.9e-56 188.5 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAG_kinase_N PF14513.6 KFP06304.1 - 2.4e-53 180.8 0.4 1.6e-51 174.9 0.4 2.4 1 1 0 1 1 1 1 Diacylglycerol kinase N-terminus DAGK_cat PF00781.24 KFP06304.1 - 6e-27 93.8 0.0 1.1e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 KFP06304.1 - 1.2e-23 82.7 25.8 6.1e-12 45.2 8.4 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_1 PF00036.32 KFP06304.1 - 2.3e-11 42.4 0.9 0.00024 20.4 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFP06304.1 - 2.5e-09 37.4 1.0 6.6e-09 36.1 0.6 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP06304.1 - 2.1e-08 33.5 0.1 0.00052 19.7 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFP06304.1 - 6.9e-07 28.5 1.9 0.0037 16.7 0.0 3.0 3 0 0 3 3 3 2 EF hand C1_2 PF03107.16 KFP06304.1 - 0.00019 21.6 15.1 0.059 13.7 1.9 2.8 2 0 0 2 2 2 2 C1 domain EF-hand_8 PF13833.6 KFP06304.1 - 0.00049 19.9 0.5 1 9.2 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFP06304.1 - 0.00095 19.5 0.2 0.005 17.2 0.2 2.1 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region TMIE PF16038.5 KFP06305.1 - 0.015 15.1 4.3 0.022 14.6 4.3 1.4 1 0 0 1 1 1 0 TMIE protein EphA2_TM PF14575.6 KFP06305.1 - 0.021 15.7 0.7 0.042 14.7 0.7 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Comm PF15957.5 KFP06305.1 - 0.036 14.4 0.0 0.049 14.0 0.0 1.2 1 0 0 1 1 1 0 Commissureless U79_P34 PF03064.16 KFP06305.1 - 0.055 12.8 2.6 0.066 12.6 2.6 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 UL40 PF10682.9 KFP06305.1 - 0.16 11.6 2.7 0.2 11.3 2.7 1.1 1 0 0 1 1 1 0 Glycoprotein of human cytomegalovirus HHV-5 Prominin PF05478.11 KFP06305.1 - 0.19 9.6 4.6 0.23 9.4 4.6 1.1 1 0 0 1 1 1 0 Prominin Rad60-SLD PF11976.8 KFP06306.1 - 2.8e-21 75.1 0.5 4.9e-20 71.1 0.5 2.0 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KFP06306.1 - 1.2e-07 31.4 0.1 2.8e-06 27.0 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin family UQ_con PF00179.26 KFP06307.1 - 2.8e-47 159.9 0.0 3.1e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme EPTP PF03736.17 KFP06308.1 - 5.2e-92 301.6 28.2 2.4e-20 72.2 1.0 7.6 7 1 0 7 7 7 7 EPTP domain Laminin_G_3 PF13385.6 KFP06308.1 - 0.00015 22.0 0.0 0.00051 20.2 0.0 1.9 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 KFP06308.1 - 0.00027 21.5 0.0 0.00051 20.6 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFP06308.1 - 0.0036 17.5 0.0 0.0097 16.1 0.0 1.7 2 0 0 2 2 2 1 Laminin G domain DUF2818 PF10993.8 KFP06308.1 - 1.5 9.4 10.2 29 5.3 0.2 4.8 5 1 0 5 5 5 0 Protein of unknown function (DUF2818) LRR_8 PF13855.6 KFP06309.1 - 5.7e-17 61.2 0.3 3.2e-14 52.4 0.0 2.1 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFP06309.1 - 2.1e-09 37.5 0.1 0.0018 18.6 0.0 2.3 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRRNT PF01462.18 KFP06309.1 - 3.5e-07 29.7 3.0 6.6e-07 28.8 3.0 1.5 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KFP06309.1 - 3.8e-06 26.7 0.3 0.47 11.2 0.1 3.8 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 KFP06309.1 - 0.00011 22.0 0.2 0.42 10.8 0.0 2.8 2 0 0 2 2 2 2 Leucine Rich repeat LRR_5 PF13306.6 KFP06309.1 - 0.0075 16.2 0.0 0.01 15.8 0.0 1.1 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) Sigma70_r4 PF04545.16 KFP06309.1 - 0.14 11.7 0.1 3 7.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 LSDAT_euk PF18139.1 KFP06310.1 - 1.1e-79 267.6 0.1 2.2e-79 266.6 0.1 1.4 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 KFP06310.1 - 1.6e-24 86.3 0.1 2.8e-24 85.5 0.1 1.3 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 KFP06310.1 - 4e-20 72.1 17.8 7.1e-20 71.3 17.8 1.4 1 0 0 1 1 1 1 Ion transport protein LDcluster4 PF18306.1 KFP06310.1 - 0.034 13.7 1.1 4.8 6.7 0.2 2.3 2 0 0 2 2 2 0 SLOG cluster4 family PKD_channel PF08016.12 KFP06310.1 - 0.065 11.9 10.2 0.031 13.0 4.5 2.4 1 1 1 2 2 2 0 Polycystin cation channel Osmo_CC PF08946.10 KFP06310.1 - 0.2 11.9 1.0 0.61 10.4 1.0 1.8 1 0 0 1 1 1 0 Osmosensory transporter coiled coil DUF1794 PF08768.11 KFP06311.1 - 1.1e-40 139.0 0.0 1.8e-40 138.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) THAP PF05485.12 KFP06311.1 - 6.9e-12 46.1 0.6 6.9e-12 46.1 0.6 2.1 2 0 0 2 2 2 1 THAP domain HrpB7 PF09486.10 KFP06311.1 - 0.0028 18.1 0.2 0.0076 16.7 0.2 1.7 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) DUF4201 PF13870.6 KFP06311.1 - 0.0041 16.9 0.4 0.0077 16.0 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) NPC1_N PF16414.5 KFP06311.1 - 0.029 13.9 0.8 0.053 13.1 0.8 1.4 1 0 0 1 1 1 0 Niemann-Pick C1 N terminus DivIC PF04977.15 KFP06311.1 - 0.36 10.6 2.3 0.62 9.9 0.3 2.1 2 0 0 2 2 2 0 Septum formation initiator Csm1_N PF18504.1 KFP06311.1 - 4.1 7.8 5.8 1.3 9.5 2.2 2.0 2 0 0 2 2 2 0 Csm1 N-terminal domain Peptidase_C54 PF03416.19 KFP06312.1 - 7.3e-102 340.5 0.0 8.8e-102 340.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Thymidylate_kin PF02223.17 KFP06313.1 - 3.4e-37 127.9 0.0 4.1e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase ING PF12998.7 KFP06314.1 - 1.8e-16 60.5 1.9 2.7e-16 60.0 1.9 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KFP06314.1 - 1.6e-06 27.9 8.1 3.5e-06 26.8 8.1 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KFP06314.1 - 0.016 15.4 1.4 0.024 14.9 0.4 1.9 2 0 0 2 2 2 0 PHD-like zinc-binding domain HD_3 PF13023.6 KFP06314.1 - 0.048 13.6 0.8 0.065 13.2 0.8 1.2 1 0 0 1 1 1 0 HD domain Spectrin_like PF18373.1 KFP06314.1 - 0.07 13.2 0.2 0.15 12.2 0.2 1.6 1 1 0 1 1 1 0 Spectrin like domain RRF PF01765.19 KFP06314.1 - 0.24 11.4 2.5 0.33 10.9 2.5 1.2 1 0 0 1 1 1 0 Ribosome recycling factor zf-C4pol PF14260.6 KFP06314.1 - 5.8 7.5 7.9 1.5 9.3 0.6 2.9 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta Gal-3-0_sulfotr PF06990.11 KFP06315.1 - 2.1e-133 445.1 4.9 2.3e-133 445.0 4.9 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 KFP06315.1 - 0.00024 21.1 0.1 0.00048 20.1 0.1 1.7 1 1 0 1 1 1 1 Sulfotransferase family BNR_2 PF13088.6 KFP06316.1 - 1.6e-34 119.5 0.0 6e-30 104.5 0.0 2.1 2 0 0 2 2 2 2 BNR repeat-like domain BNR_3 PF13859.6 KFP06316.1 - 1e-05 25.0 0.0 1.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 KFP06316.1 - 0.00096 18.8 3.8 0.67 10.2 0.2 3.8 3 0 0 3 3 3 2 BNR/Asp-box repeat L6_membrane PF05805.12 KFP06317.1 - 1.1e-57 194.8 11.9 1.2e-57 194.6 11.9 1.0 1 0 0 1 1 1 1 L6 membrane protein UBX PF00789.20 KFP06318.1 - 4e-19 68.6 0.0 7.4e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.6 KFP06318.1 - 2.1e-15 56.6 0.1 3.9e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 KFP06318.1 - 4.1e-08 32.9 0.1 1.2e-06 28.2 0.0 2.6 2 0 0 2 2 2 1 UBA-like domain UIM PF02809.20 KFP06318.1 - 0.032 14.1 2.8 0.11 12.5 2.8 2.0 1 0 0 1 1 1 0 Ubiquitin interaction motif Thioredox_DsbH PF03190.15 KFP06318.1 - 0.035 14.1 0.2 0.06 13.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.6 KFP06318.1 - 0.12 12.9 0.1 0.27 11.7 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain Prok-RING_4 PF14447.6 KFP06319.1 - 3.7e-05 23.5 8.5 0.00015 21.6 8.5 2.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KFP06319.1 - 0.24 11.8 12.3 1 9.8 12.3 2.2 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 KFP06319.1 - 0.37 10.7 12.4 1.5 8.8 12.4 2.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP06319.1 - 0.79 9.6 15.3 0.038 13.9 9.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP06319.1 - 1.7 8.7 18.3 0.033 14.2 10.9 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFP06319.1 - 1.7 8.6 13.0 5.5 6.9 13.0 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.32 KFP06320.1 - 3.7e-15 56.1 1.3 0.0031 18.3 0.0 6.2 5 1 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP06320.1 - 1.4e-05 25.3 0.0 0.14 12.5 0.0 3.5 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain LRR_8 PF13855.6 KFP06321.1 - 4e-51 170.6 61.8 2.5e-10 40.0 2.4 9.1 6 2 4 10 10 10 9 Leucine rich repeat LRR_4 PF12799.7 KFP06321.1 - 3.2e-27 94.1 59.2 0.00013 22.2 0.4 11.5 7 2 6 14 14 14 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP06321.1 - 2.3e-10 39.5 56.1 4.8 8.1 0.3 17.4 19 1 0 19 19 19 2 Leucine Rich Repeat LRR_9 PF14580.6 KFP06321.1 - 7.2e-05 22.3 16.0 0.051 13.1 0.1 5.2 1 1 3 5 5 5 3 Leucine-rich repeat LRR_5 PF13306.6 KFP06321.1 - 0.0011 18.9 0.1 0.2 11.6 0.0 3.7 3 1 2 5 5 5 2 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KFP06321.1 - 0.63 10.2 69.6 5.1 7.4 0.1 15.7 18 0 0 18 18 18 0 Leucine Rich repeat CEP19 PF14933.6 KFP06322.1 - 8.8e-36 123.7 3.8 9.7e-36 123.6 3.8 1.0 1 0 0 1 1 1 1 CEP19-like protein PIG-X PF08320.12 KFP06323.1 - 1.5e-40 139.4 0.1 1.7e-40 139.2 0.1 1.0 1 0 0 1 1 1 1 PIG-X / PBN1 Pkinase PF00069.25 KFP06324.1 - 5.9e-74 248.7 0.0 8.2e-74 248.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP06324.1 - 1.6e-47 161.9 0.0 2.6e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KFP06324.1 - 3.8e-25 88.0 0.0 9e-25 86.8 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KFP06324.1 - 3.5e-08 33.1 0.1 0.00035 20.0 0.0 2.4 1 1 1 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KFP06324.1 - 3.3e-06 26.1 0.0 6.8e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP06324.1 - 0.0035 17.3 0.0 0.046 13.6 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFP06324.1 - 0.0065 15.5 0.8 0.038 12.9 0.8 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFP06324.1 - 0.03 13.7 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MIP PF00230.20 KFP06325.1 - 2.6e-09 37.1 7.1 4.1e-09 36.5 7.1 1.2 1 0 0 1 1 1 1 Major intrinsic protein Gal-3-0_sulfotr PF06990.11 KFP06326.1 - 3.1e-121 405.0 0.1 3.5e-121 404.9 0.1 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 KFP06326.1 - 3.4e-06 27.1 0.0 9.7e-05 22.4 0.0 2.5 1 1 0 1 1 1 1 Sulfotransferase family RhoGEF PF00621.20 KFP06327.1 - 2e-46 158.6 7.3 2e-46 158.6 7.3 2.1 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 KFP06327.1 - 2.8e-10 40.7 0.7 5.8e-10 39.6 0.7 1.6 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.28 KFP06327.1 - 7.8e-10 38.2 2.0 1.5e-09 37.3 2.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP06327.1 - 6.6e-09 35.5 0.1 1.2e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP06327.1 - 8.9e-08 31.7 0.0 1.7e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Cor1 PF04803.12 KFP06327.1 - 3.2 8.0 10.4 0.69 10.1 0.8 3.2 3 1 1 4 4 4 0 Cor1/Xlr/Xmr conserved region 7tm_1 PF00001.21 KFP06328.1 - 7.7e-06 25.4 27.5 3.4e-05 23.3 27.6 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP06328.1 - 0.0077 16.0 19.1 0.026 14.3 19.1 1.8 1 1 0 1 1 1 1 Olfactory receptor MadM PF03818.13 KFP06328.1 - 0.14 12.1 0.3 0.14 12.1 0.3 2.1 2 0 0 2 2 2 0 Malonate/sodium symporter MadM subunit Kelch_1 PF01344.25 KFP06329.1 - 3.1e-35 119.5 4.4 1.5e-11 43.6 0.0 6.9 6 1 0 6 6 6 5 Kelch motif BACK PF07707.15 KFP06329.1 - 6.8e-31 106.4 0.3 1.6e-30 105.2 0.3 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFP06329.1 - 2e-29 100.9 0.1 5.6e-05 23.3 0.0 6.1 4 2 2 6 6 6 5 Kelch motif BTB PF00651.31 KFP06329.1 - 3.2e-27 95.0 4.5 3.9e-27 94.7 2.5 2.1 1 1 1 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 KFP06329.1 - 2.5e-24 84.3 0.3 0.00016 21.5 0.0 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 KFP06329.1 - 4.4e-14 52.2 0.0 0.075 13.1 0.0 6.2 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP06329.1 - 3.6e-13 49.4 1.3 0.021 15.1 0.0 6.3 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP06329.1 - 1.4e-10 40.9 1.4 0.00077 19.4 0.0 5.6 6 0 0 6 6 6 2 Kelch motif DUF3342 PF11822.8 KFP06329.1 - 9.3e-05 22.6 1.5 0.0012 19.0 0.6 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) Kelch_1 PF01344.25 KFP06330.1 - 2.9e-44 148.4 23.7 8e-14 51.0 0.1 7.2 7 1 0 7 7 7 6 Kelch motif BACK PF07707.15 KFP06330.1 - 2.8e-32 110.9 0.6 2.8e-32 110.9 0.6 1.6 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFP06330.1 - 5.5e-29 99.5 8.0 1.8e-05 24.9 0.0 6.5 3 1 3 6 6 6 6 Kelch motif BTB PF00651.31 KFP06330.1 - 7.6e-29 100.2 1.4 1.7e-28 99.0 0.8 2.0 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.6 KFP06330.1 - 6.5e-26 90.1 3.2 5.2e-05 23.4 0.1 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP06330.1 - 3.8e-21 74.2 11.7 1.3e-05 24.9 0.1 6.6 6 1 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KFP06330.1 - 4e-21 74.8 1.4 0.00031 20.7 0.0 6.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP06330.1 - 2.5e-08 33.7 9.0 0.094 12.7 0.1 5.8 6 0 0 6 6 6 2 Kelch motif DUF3342 PF11822.8 KFP06330.1 - 0.014 15.5 0.7 0.034 14.3 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) YEATS PF03366.16 KFP06331.1 - 3.5e-25 87.8 0.7 3.5e-25 87.8 0.7 1.8 2 0 0 2 2 2 1 YEATS family Aminotran_1_2 PF00155.21 KFP06332.1 - 1.1e-58 199.1 0.0 1.3e-58 198.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KFP06332.1 - 0.0001 21.7 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KFP06332.1 - 0.00048 19.2 0.0 0.00072 18.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cyd_oper_YbgE PF09600.10 KFP06332.1 - 0.072 13.5 0.0 16 5.9 0.0 2.4 2 0 0 2 2 2 0 Cyd operon protein YbgE (Cyd_oper_YbgE) Raf1_HTH PF18579.1 KFP06332.1 - 0.084 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain AMOP PF03782.17 KFP06333.1 - 1.2e-24 87.1 5.1 1.2e-24 87.1 5.1 2.0 2 0 0 2 2 2 1 AMOP domain TSP_1 PF00090.19 KFP06333.1 - 3.8e-07 30.2 12.4 3.8e-07 30.2 12.4 2.6 2 0 0 2 2 2 1 Thrombospondin type 1 domain Asparaginase_2 PF01112.18 KFP06334.1 - 8.4e-52 176.1 0.1 1.4e-51 175.4 0.1 1.4 1 0 0 1 1 1 1 Asparaginase Methyltransf_11 PF08241.12 KFP06335.1 - 2.5e-22 79.3 0.0 4e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP06335.1 - 1.2e-16 61.2 0.0 1.9e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP06335.1 - 1.6e-15 57.3 0.0 2.4e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP06335.1 - 3.5e-12 46.4 0.0 5.4e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP06335.1 - 1.9e-10 41.3 0.0 3e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFP06335.1 - 6.7e-10 38.7 0.0 1.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 KFP06335.1 - 1.7e-06 26.9 0.0 2.3e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.7 KFP06335.1 - 0.0059 16.6 0.0 0.0088 16.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFP06335.1 - 0.01 15.4 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.15 KFP06335.1 - 0.013 15.3 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase MetW PF07021.12 KFP06335.1 - 0.015 14.9 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_7 PF03492.15 KFP06335.1 - 0.15 11.3 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase Macro PF01661.21 KFP06336.1 - 4.9e-43 145.9 0.4 8.6e-43 145.1 0.4 1.4 1 0 0 1 1 1 1 Macro domain LRR_8 PF13855.6 KFP06337.1 - 2.7e-30 103.9 39.5 3.1e-13 49.3 3.8 6.0 3 1 3 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 KFP06337.1 - 2.6e-15 56.3 41.9 0.00019 21.7 2.6 7.2 3 1 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP06337.1 - 5.6e-10 39.0 10.0 0.00023 20.7 1.6 3.5 2 1 1 3 3 3 3 Leucine-rich repeat LRR_5 PF13306.6 KFP06337.1 - 2.3e-08 34.0 0.3 0.00012 22.0 0.0 3.8 1 1 3 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRRNT PF01462.18 KFP06337.1 - 0.0003 20.4 3.9 0.00088 18.9 2.2 2.5 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRRCT PF01463.24 KFP06337.1 - 0.0024 18.3 0.0 0.007 16.8 0.0 1.9 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain fn3 PF00041.21 KFP06337.1 - 0.01 16.2 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III domain TPKR_C2 PF16920.5 KFP06337.1 - 0.073 13.2 0.8 0.27 11.4 0.2 2.4 2 0 0 2 2 2 0 Tyrosine-protein kinase receptor C2 Ig-like domain Kinesin PF00225.23 KFP06338.1 - 1.1e-110 369.7 0.7 1.1e-110 369.7 0.7 3.9 3 1 1 5 5 5 1 Kinesin motor domain Microtub_bd PF16796.5 KFP06338.1 - 1.5e-23 83.4 0.2 1.5e-23 83.4 0.2 2.9 2 0 0 2 2 2 1 Microtubule binding PX PF00787.24 KFP06338.1 - 3.4e-16 59.2 0.5 3.4e-16 59.2 0.5 3.3 2 1 0 2 2 2 1 PX domain Kinesin_assoc PF16183.5 KFP06338.1 - 2.9e-09 37.3 3.8 1.1e-05 25.6 0.3 6.4 2 2 4 6 6 6 3 Kinesin-associated Yop-YscD_cpl PF16697.5 KFP06338.1 - 3.3e-05 24.1 0.8 0.00024 21.3 0.0 2.8 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain DUF2326 PF10088.9 KFP06338.1 - 0.031 14.0 0.0 0.031 14.0 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised protein conserved in bacteria (DUF2326) RRM_1 PF00076.22 KFP06339.1 - 3.6e-27 94.0 0.7 7.6e-15 54.5 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP06339.1 - 1.2e-08 34.7 0.0 0.0004 20.2 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KFP06339.1 - 1.2e-07 31.4 0.2 0.0059 16.2 0.1 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_dom-like PF14714.6 KFP06339.1 - 0.051 13.9 0.1 0.46 10.8 0.1 2.4 2 0 0 2 2 2 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal DUF1027 PF06265.11 KFP06339.1 - 0.18 11.8 0.6 0.77 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1027) SH3_2 PF07653.17 KFP06340.1 - 3.6e-19 68.2 0.0 5e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFP06340.1 - 0.00098 18.9 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain ISK_Channel PF02060.15 KFP06340.1 - 0.11 12.3 0.1 0.17 11.6 0.1 1.4 1 1 0 1 1 1 0 Slow voltage-gated potassium channel RVT_1 PF00078.27 KFP06341.1 - 0.14 11.7 0.0 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_S8 PF00082.22 KFP06342.1 - 1.9e-42 145.6 2.4 2.4e-42 145.2 2.4 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KFP06342.1 - 1.3e-25 89.2 0.1 2.7e-25 88.2 0.1 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KFP06342.1 - 1e-08 35.8 3.2 1.8e-08 35.0 3.2 1.5 1 0 0 1 1 1 1 Peptidase S8 pro-domain Peptidase_S8_N PF16361.5 KFP06342.1 - 0.016 15.7 0.0 0.033 14.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal of Subtilase family Minor_tail_Z PF06763.11 KFP06342.1 - 1.8 8.3 4.1 0.99 9.2 0.1 2.1 2 0 0 2 2 2 0 Prophage minor tail protein Z (GPZ) Filament PF00038.21 KFP06343.1 - 1.3e-22 80.8 44.7 2.4e-22 79.9 21.0 2.9 4 0 0 4 4 4 2 Intermediate filament protein TPR_MLP1_2 PF07926.12 KFP06343.1 - 0.0029 17.6 10.5 0.0029 17.6 10.5 4.9 4 1 1 5 5 5 1 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KFP06343.1 - 0.0045 15.9 13.6 0.0045 15.9 13.6 3.8 3 1 1 4 4 4 1 Spc7 kinetochore protein DUF5065 PF16723.5 KFP06343.1 - 0.14 12.2 1.2 0.34 11.0 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5065) Lectin_N PF03954.14 KFP06343.1 - 0.26 11.1 7.1 0.04 13.7 1.2 2.7 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain LemA PF04011.12 KFP06343.1 - 0.84 9.5 21.2 0.066 13.1 2.4 3.5 2 1 1 3 3 3 0 LemA family PSI_PsaF PF02507.15 KFP06343.1 - 0.98 9.2 8.2 2.4 7.9 0.9 3.7 3 1 0 3 3 3 0 Photosystem I reaction centre subunit III Baculo_PEP_C PF04513.12 KFP06343.1 - 2 8.4 14.3 0.23 11.5 1.0 3.4 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus 7tm_1 PF00001.21 KFP06344.1 - 8.1e-47 159.7 24.0 1e-46 159.4 24.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP06344.1 - 1.9e-05 24.2 27.0 2.5e-05 23.8 27.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP06345.1 - 9.6e-06 25.5 0.6 9.6e-06 25.5 0.6 1.1 1 0 0 1 1 1 1 Olfactory receptor EF-hand_4 PF12763.7 KFP06346.1 - 2.4e-42 143.1 0.0 1.2e-22 79.8 0.0 3.6 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KFP06346.1 - 1.4e-12 46.2 2.9 0.0026 17.2 0.1 4.7 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 KFP06346.1 - 5.1e-10 38.5 0.8 0.051 13.5 0.2 5.2 5 0 0 5 5 5 2 EF-hand domain EzrA PF06160.12 KFP06346.1 - 1.6e-06 26.6 31.5 2.6e-06 25.9 31.5 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA EF-hand_7 PF13499.6 KFP06346.1 - 2.2e-05 24.8 5.5 0.11 12.9 0.1 4.3 4 0 0 4 4 3 2 EF-hand domain pair Macoilin PF09726.9 KFP06346.1 - 2.5e-05 23.1 16.8 3.7e-05 22.5 16.8 1.2 1 0 0 1 1 1 1 Macoilin family BicD PF09730.9 KFP06346.1 - 0.00056 18.5 27.5 0.00083 17.9 27.5 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D EF-hand_5 PF13202.6 KFP06346.1 - 0.00079 18.8 3.5 0.38 10.3 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFP06346.1 - 0.00082 19.2 1.8 0.16 11.9 0.2 3.6 4 0 0 4 4 4 1 EF-hand domain pair Tropomyosin PF00261.20 KFP06346.1 - 0.0017 17.8 20.4 0.0017 17.8 20.4 2.4 2 1 1 3 3 2 1 Tropomyosin ERM PF00769.19 KFP06346.1 - 0.0028 17.5 29.6 0.0028 17.5 29.6 2.2 2 0 0 2 2 2 1 Ezrin/radixin/moesin family DUF4201 PF13870.6 KFP06346.1 - 0.0087 15.8 19.9 0.0087 15.8 19.9 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) Atg14 PF10186.9 KFP06346.1 - 0.038 13.1 41.5 0.36 9.9 8.3 3.2 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 CALCOCO1 PF07888.11 KFP06346.1 - 0.062 12.2 37.7 0.12 11.3 37.7 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4763 PF15960.5 KFP06346.1 - 0.2 10.9 40.8 0.04 13.2 9.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) Prominin PF05478.11 KFP06346.1 - 0.23 9.4 22.5 0.37 8.7 22.5 1.2 1 0 0 1 1 1 0 Prominin DUF948 PF06103.11 KFP06346.1 - 0.49 10.7 18.7 1.8 8.9 3.1 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 KFP06346.1 - 0.5 10.4 29.8 0.027 14.5 4.9 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF745 PF05335.13 KFP06346.1 - 0.52 10.0 33.3 2.3 7.9 18.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) IFT57 PF10498.9 KFP06346.1 - 0.6 9.0 35.9 2.8 6.8 35.8 2.0 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 LMBR1 PF04791.16 KFP06346.1 - 1 8.2 19.9 1.6 7.5 19.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein HMMR_N PF15905.5 KFP06346.1 - 1.1 8.7 44.4 1.6 8.1 16.3 2.5 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal TMPIT PF07851.13 KFP06346.1 - 1.1 8.4 33.4 1.2 8.3 14.3 2.2 1 1 1 2 2 2 0 TMPIT-like protein AAA_13 PF13166.6 KFP06346.1 - 1.2 7.7 31.5 7 5.2 31.6 1.8 1 1 0 1 1 1 0 AAA domain ATG16 PF08614.11 KFP06346.1 - 3.4 7.8 55.9 0.24 11.6 31.3 3.1 2 1 1 3 3 2 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 KFP06346.1 - 4.6 7.6 46.4 0.37 11.2 19.9 2.7 2 1 1 3 3 3 0 Fez1 FUSC PF04632.12 KFP06346.1 - 4.7 5.6 6.9 7.3 5.0 6.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Med30 PF11315.8 KFP06346.1 - 5.1 7.3 26.9 3.9 7.7 23.1 2.5 1 1 2 3 3 3 0 Mediator complex subunit 30 MAD PF05557.13 KFP06346.1 - 6.2 5.1 44.8 31 2.7 44.6 1.8 1 1 0 1 1 1 0 Mitotic checkpoint protein FlaC_arch PF05377.11 KFP06346.1 - 8.8 6.8 30.3 1.3 9.5 2.1 4.7 2 1 1 4 4 4 0 Flagella accessory protein C (FlaC) UPF0240 PF06784.11 KFP06346.1 - 9.3 6.3 13.3 25 4.9 13.3 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) GAS PF13851.6 KFP06346.1 - 9.5 5.5 43.3 4.3 6.6 19.3 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding zf-C2H2 PF00096.26 KFP06347.1 - 4.1e-15 55.3 29.5 9.4e-06 25.8 4.2 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP06347.1 - 3.8e-10 39.7 13.1 5e-07 29.9 4.3 4.7 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP06347.1 - 2.4e-08 34.1 21.5 0.0049 17.6 3.2 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP06347.1 - 0.026 14.8 4.1 2 8.8 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KFP06347.1 - 0.11 13.1 5.8 5.6 7.7 1.8 2.9 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-met PF12874.7 KFP06347.1 - 0.32 11.4 9.5 2.5 8.6 0.7 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KFP06347.1 - 0.36 11.3 5.9 12 6.4 0.1 2.9 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Adap_comp_sub PF00928.21 KFP06348.1 - 3.3e-87 292.2 1.2 8.5e-79 264.6 0.2 2.5 3 0 0 3 3 3 2 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFP06348.1 - 4.2e-05 23.5 0.8 6.9e-05 22.8 0.8 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF5482 PF17579.2 KFP06348.1 - 0.017 15.0 0.0 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5482) DUF1754 PF08555.10 KFP06349.1 - 7.7e-08 33.0 19.6 5.9e-05 23.8 9.8 2.6 2 1 1 3 3 3 2 Eukaryotic family of unknown function (DUF1754) AAA_10 PF12846.7 KFP06349.1 - 0.008 15.1 2.3 0.0096 14.9 2.3 1.0 1 0 0 1 1 1 1 AAA-like domain UPF0172 PF03665.13 KFP06349.1 - 0.021 14.9 0.4 0.028 14.5 0.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) EF-hand_7 PF13499.6 KFP06350.1 - 4.2e-15 55.9 2.3 2.4e-12 47.1 1.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFP06350.1 - 2.3e-11 42.4 4.7 2.5e-05 23.5 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KFP06350.1 - 2.7e-10 39.3 4.2 0.0014 18.4 0.3 3.8 3 1 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 KFP06350.1 - 7.5e-06 25.7 2.8 0.00093 19.0 0.6 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP06350.1 - 0.00026 20.4 2.2 0.0026 17.2 0.2 2.9 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.9 KFP06350.1 - 0.052 13.9 0.6 0.12 12.7 0.6 1.6 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_13 PF17958.1 KFP06350.1 - 0.12 12.2 0.0 18 5.2 0.0 3.1 2 1 0 2 2 2 0 EF-hand domain Dockerin_1 PF00404.18 KFP06350.1 - 1.7 8.9 4.3 0.43 10.8 0.8 1.8 2 1 0 2 2 2 0 Dockerin type I domain Ras PF00071.22 KFP06351.1 - 8.9e-45 152.2 0.1 1.1e-44 151.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP06351.1 - 2.9e-15 56.5 0.2 6.2e-15 55.5 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP06351.1 - 7.7e-06 25.5 0.2 9.1e-06 25.2 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF3963 PF13124.6 KFP06351.1 - 0.058 13.4 0.4 0.11 12.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) Tropomyosin PF00261.20 KFP06352.1 - 1.1e-102 342.4 85.1 1.9e-97 325.3 61.4 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 KFP06352.1 - 1e-39 135.9 71.9 1.1e-35 122.9 40.1 3.1 1 1 0 2 2 2 2 Tropomyosin like Laminin_II PF06009.12 KFP06352.1 - 6.1e-08 32.8 32.4 0.00026 21.0 7.4 3.3 1 1 2 3 3 3 2 Laminin Domain II CLZ PF16526.5 KFP06352.1 - 2.9e-07 30.7 46.9 4.3e-06 27.0 8.7 5.1 2 2 3 5 5 5 3 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Laminin_I PF06008.14 KFP06352.1 - 2.7e-05 24.0 49.8 0.00011 22.0 13.7 3.2 1 1 2 3 3 3 2 Laminin Domain I ATG16 PF08614.11 KFP06352.1 - 0.00029 21.1 56.8 0.0041 17.4 18.6 3.5 1 1 1 2 2 1 1 Autophagy protein 16 (ATG16) ERM PF00769.19 KFP06352.1 - 0.0021 17.9 68.2 0.28 11.0 23.3 2.7 1 1 1 2 2 2 2 Ezrin/radixin/moesin family BST2 PF16716.5 KFP06352.1 - 0.0022 18.5 7.7 0.0022 18.5 7.7 5.0 1 1 4 5 5 5 1 Bone marrow stromal antigen 2 TMF_DNA_bd PF12329.8 KFP06352.1 - 0.005 16.8 14.2 0.005 16.8 14.2 6.4 1 1 4 6 6 5 3 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 KFP06352.1 - 0.0053 16.8 65.2 0.016 15.2 30.9 2.5 2 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 KFP06352.1 - 0.0072 15.7 8.3 0.0072 15.7 8.3 3.7 1 1 3 4 4 4 1 Protein of unknown function (DUF3450) AAA_13 PF13166.6 KFP06352.1 - 0.0078 14.9 46.5 0.21 10.2 26.2 2.0 1 1 1 2 2 2 2 AAA domain DHR10 PF18595.1 KFP06352.1 - 0.015 15.4 28.3 0.015 15.4 28.3 3.4 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain XhlA PF10779.9 KFP06352.1 - 0.019 15.2 2.6 0.019 15.2 2.6 6.5 1 1 6 7 7 7 0 Haemolysin XhlA Lebercilin PF15619.6 KFP06352.1 - 0.027 14.1 58.9 0.12 12.0 16.8 3.3 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease MscS_porin PF12795.7 KFP06352.1 - 0.029 13.9 43.2 0.092 12.3 20.0 3.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain COG2 PF06148.11 KFP06352.1 - 0.048 13.8 1.4 0.048 13.8 1.4 4.1 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 KFP06352.1 - 0.073 13.1 31.4 0.079 13.0 4.1 3.7 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) SNARE PF05739.19 KFP06352.1 - 0.091 12.8 5.9 2.3 8.3 0.1 3.9 3 1 1 4 4 4 0 SNARE domain HrpB7 PF09486.10 KFP06352.1 - 0.094 13.1 50.1 0.046 14.1 13.3 4.4 1 1 3 4 4 4 0 Bacterial type III secretion protein (HrpB7) DUF745 PF05335.13 KFP06352.1 - 0.17 11.6 46.4 0.86 9.3 7.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF745) Spc7 PF08317.11 KFP06352.1 - 0.22 10.4 62.6 0.12 11.2 26.9 2.7 1 1 2 3 3 3 0 Spc7 kinetochore protein SlyX PF04102.12 KFP06352.1 - 0.23 12.1 45.1 0.21 12.2 1.2 5.6 1 1 4 5 5 5 0 SlyX FPP PF05911.11 KFP06352.1 - 0.27 9.4 60.1 0.046 11.9 30.6 2.9 1 1 2 3 3 3 0 Filament-like plant protein, long coiled-coil Golgin_A5 PF09787.9 KFP06352.1 - 0.3 10.5 53.5 4 6.8 21.5 2.7 1 1 2 3 3 3 0 Golgin subfamily A member 5 EzrA PF06160.12 KFP06352.1 - 0.31 9.2 54.6 0.24 9.5 6.4 3.2 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA Exonuc_VII_L PF02601.15 KFP06352.1 - 0.38 10.3 32.9 3.7 7.0 16.8 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF3584 PF12128.8 KFP06352.1 - 0.47 7.9 54.4 0.41 8.1 23.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) NPV_P10 PF05531.12 KFP06352.1 - 0.48 10.9 19.3 3.2 8.3 2.3 4.5 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 KFP06352.1 - 0.8 10.2 39.0 0.54 10.8 6.5 4.4 1 1 3 4 4 4 0 Protein of unknown function DUF16 ADIP PF11559.8 KFP06352.1 - 0.87 9.7 48.3 1.5 8.9 6.9 4.2 1 1 4 5 5 5 0 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 KFP06352.1 - 0.92 9.9 51.1 11 6.4 25.0 3.1 1 1 1 2 2 2 0 Fez1 Fib_alpha PF08702.10 KFP06352.1 - 1.3 9.2 30.8 0.25 11.5 6.5 3.3 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family FH2 PF02181.23 KFP06352.1 - 1.8 7.6 38.7 0.18 10.9 8.8 3.2 1 1 2 3 3 3 0 Formin Homology 2 Domain GAS PF13851.6 KFP06352.1 - 2 7.7 63.5 0.52 9.6 23.3 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Flagellin_N PF00669.20 KFP06352.1 - 2.1 8.5 17.7 2 8.5 5.6 3.8 1 1 3 4 4 4 0 Bacterial flagellin N-terminal helical region FUSC PF04632.12 KFP06352.1 - 2.6 6.5 16.5 4.2 5.8 9.6 2.1 1 1 0 2 2 2 0 Fusaric acid resistance protein family Uds1 PF15456.6 KFP06352.1 - 2.7 8.2 48.0 0.89 9.7 15.2 5.2 1 1 4 5 5 5 0 Up-regulated During Septation DUF1794 PF08768.11 KFP06352.1 - 2.8 7.9 5.1 28 4.6 0.2 3.0 2 2 1 3 3 3 0 Domain of unknown function (DUF1794) HemX PF04375.14 KFP06352.1 - 3.1 7.0 35.6 1.1 8.4 13.4 3.2 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase LOH1CR12 PF10158.9 KFP06352.1 - 4.8 7.2 14.3 0.86 9.6 2.2 3.3 1 1 1 3 3 3 0 Tumour suppressor protein T3SSipB PF16535.5 KFP06352.1 - 5.2 7.5 48.1 1.2 9.6 14.2 4.5 1 1 3 4 4 4 0 Type III cell invasion protein SipB DUF2721 PF11026.8 KFP06352.1 - 7.1 6.5 6.3 9.2 6.2 0.2 3.1 2 1 2 4 4 2 0 Protein of unknown function (DUF2721) TTKRSYEDQ PF10212.9 KFP06352.1 - 7.5 5.4 35.5 2.1 7.3 10.8 2.4 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein ApoO PF09769.9 KFP06352.1 - 7.9 6.5 9.2 8.8 6.3 0.4 3.8 1 1 1 3 3 3 0 Apolipoprotein O SH3BP5 PF05276.14 KFP06352.1 - 8.2 6.2 44.6 1.1 9.0 8.9 4.0 1 1 2 3 3 3 0 SH3 domain-binding protein 5 (SH3BP5) TGF_beta PF00019.20 KFP06353.1 - 1.5e-31 109.4 0.1 1.5e-31 109.4 0.1 1.5 2 0 0 2 2 2 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFP06353.1 - 2.9e-15 56.7 0.0 7.6e-09 35.7 0.0 2.2 1 1 1 2 2 2 2 TGF-beta propeptide CI-B14_5a PF07347.12 KFP06354.1 - 2.7e-29 100.9 1.2 4.5e-29 100.2 1.2 1.4 1 1 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Ribosomal_S28e PF01200.18 KFP06355.1 - 2.9e-31 107.3 1.1 3.1e-31 107.1 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Ank_2 PF12796.7 KFP06356.1 - 4.7e-27 94.4 9.0 2.3e-08 34.5 1.7 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP06356.1 - 4.8e-27 94.0 8.0 1.5e-10 41.4 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KFP06356.1 - 1.2e-24 85.6 6.0 1.2e-06 28.6 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KFP06356.1 - 1.2e-23 82.9 11.3 2.6e-10 40.4 0.2 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP06356.1 - 3.9e-20 69.8 5.0 2.3e-05 24.4 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat CobT PF06213.12 KFP06356.1 - 8.6 5.7 8.6 15 4.8 8.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ank_2 PF12796.7 KFP06357.1 - 2e-41 140.4 2.0 1.2e-17 64.3 0.1 4.8 2 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KFP06357.1 - 4.7e-36 121.7 7.3 9.2e-06 25.9 0.0 7.6 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.6 KFP06357.1 - 2.6e-33 113.9 2.5 1.6e-08 34.9 0.1 6.6 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP06357.1 - 7.2e-31 102.8 3.9 7.1e-05 22.9 0.0 8.4 8 1 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 KFP06357.1 - 8.1e-31 105.7 7.9 3.3e-08 33.6 0.2 7.1 3 1 4 7 7 7 7 Ankyrin repeats (many copies) TPR_12 PF13424.6 KFP06357.1 - 0.00073 19.8 0.1 0.057 13.7 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFP06357.1 - 0.029 14.5 3.4 0.18 12.0 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFP06357.1 - 0.083 12.8 2.5 0.44 10.5 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TRIF-NTD PF17798.1 KFP06358.1 - 2.2e-46 157.8 0.7 3.5e-46 157.2 0.7 1.3 1 0 0 1 1 1 1 TRIF N-terminal domain TIR_2 PF13676.6 KFP06358.1 - 5.3e-05 23.8 0.0 0.00011 22.7 0.0 1.5 1 0 0 1 1 1 1 TIR domain Perilipin PF03036.16 KFP06359.1 - 4.3e-133 444.1 16.2 4.8e-133 444.0 16.2 1.0 1 0 0 1 1 1 1 Perilipin family CdvA PF18822.1 KFP06359.1 - 0.032 14.1 0.1 0.61 9.9 0.1 2.6 2 0 0 2 2 2 0 CdvA-like coiled-coil domain PHA_gran_rgn PF09650.10 KFP06359.1 - 0.053 13.8 0.1 1.4 9.3 0.1 2.8 2 0 0 2 2 2 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) DUF2452 PF10504.9 KFP06359.1 - 0.064 12.7 7.3 0.8 9.2 0.0 3.6 2 2 2 4 4 4 0 Protein of unknown function (DUF2452) CRIC_ras_sig PF10534.9 KFP06359.1 - 0.35 11.1 7.6 4.6 7.5 0.1 3.7 4 0 0 4 4 4 0 Connector enhancer of kinase suppressor of ras Med9 PF07544.13 KFP06359.1 - 0.71 10.0 4.6 21 5.3 0.1 3.5 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 COG5 PF10392.9 KFP06359.1 - 1.5 9.0 7.1 1 9.5 0.1 3.3 3 1 1 4 4 4 0 Golgi transport complex subunit 5 TTD PF12148.8 KFP06360.1 - 7.6e-67 224.0 0.4 1.4e-66 223.2 0.4 1.4 1 0 0 1 1 1 1 Tandem tudor domain within UHRF1 SAD_SRA PF02182.17 KFP06360.1 - 9.9e-57 191.0 0.2 2.5e-56 189.7 0.2 1.8 1 0 0 1 1 1 1 SAD/SRA domain PHD PF00628.29 KFP06360.1 - 2.1e-12 46.7 7.6 2.1e-12 46.7 7.6 3.6 3 1 0 3 3 1 1 PHD-finger zf-C3HC4_2 PF13923.6 KFP06360.1 - 0.00029 20.6 12.8 0.00029 20.6 12.8 3.0 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP06360.1 - 0.00071 19.4 13.2 0.00071 19.4 13.2 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP06360.1 - 0.0013 18.6 9.9 0.0013 18.6 9.9 4.1 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.6 KFP06360.1 - 0.0014 18.1 0.6 0.0014 18.1 0.6 2.9 3 0 0 3 3 2 1 PHD-finger Prok-RING_4 PF14447.6 KFP06360.1 - 0.0017 18.2 9.1 0.0017 18.2 9.1 3.1 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KFP06360.1 - 0.0052 16.9 7.7 0.0052 16.9 7.7 3.0 2 1 0 2 2 1 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 KFP06360.1 - 0.0088 16.4 12.5 0.0088 16.4 12.5 3.1 2 1 1 3 3 3 2 Ring finger domain Agenet PF05641.12 KFP06360.1 - 0.03 14.8 0.1 18 5.9 0.1 2.9 2 1 0 2 2 2 0 Agenet domain Tudor-knot PF11717.8 KFP06360.1 - 0.034 14.0 0.0 2 8.4 0.0 2.5 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain HicB-like_2 PF15970.5 KFP06360.1 - 0.1 12.7 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system DUF3592 PF12158.8 KFP06360.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) XPA_N PF01286.18 KFP06360.1 - 0.95 9.6 9.2 2.1 8.5 0.0 4.1 3 0 0 3 3 3 0 XPA protein N-terminal JmjC PF02373.22 KFP06361.1 - 3e-44 150.1 0.0 7.8e-44 148.7 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 KFP06361.1 - 1.5e-35 121.7 8.9 1.5e-35 121.7 8.9 2.1 2 0 0 2 2 2 1 PHD-zinc-finger like domain Tudor_2 PF18104.1 KFP06361.1 - 8.5e-32 108.5 1.4 1.4e-16 59.9 0.4 2.5 2 0 0 2 2 2 2 Jumonji domain-containing protein 2A Tudor domain zf-HC5HC2H PF13771.6 KFP06361.1 - 8.3e-18 64.4 5.2 8.3e-18 64.4 5.2 3.2 2 1 1 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KFP06361.1 - 1.2e-13 50.3 15.5 2.1e-13 49.6 6.9 2.9 2 0 0 2 2 2 1 PHD-finger JmjN PF02375.17 KFP06361.1 - 3.4e-13 49.3 0.0 1.1e-12 47.7 0.0 2.0 1 0 0 1 1 1 1 jmjN domain PHD PF00628.29 KFP06361.1 - 1.3e-06 28.1 22.2 4.8e-05 23.2 2.7 3.5 3 0 0 3 3 3 2 PHD-finger LBR_tudor PF09465.10 KFP06361.1 - 6.7e-06 25.8 0.7 0.13 12.1 0.0 2.6 2 0 0 2 2 2 2 Lamin-B receptor of TUDOR domain Tudor_3 PF18115.1 KFP06361.1 - 0.0089 15.9 0.5 1.1 9.1 0.2 2.5 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 KFP06361.1 - 0.023 14.7 0.1 0.19 11.8 0.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4537) Rad9_Rad53_bind PF08605.10 KFP06361.1 - 0.03 14.5 0.1 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 Fungal Rad9-like Rad53-binding SLX9 PF15341.6 KFP06361.1 - 0.5 10.8 6.7 1.2 9.5 6.7 1.6 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 Tmemb_161AB PF10268.9 KFP06365.1 - 1.9e-148 495.1 6.0 2.1e-148 494.9 6.0 1.0 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB KleE PF17394.2 KFP06365.1 - 0.74 10.1 4.2 0.39 10.9 1.0 2.1 2 0 0 2 2 2 0 Uncharacterized KleE stable inheritance protein Mito_carr PF00153.27 KFP06366.1 - 4.8e-72 238.0 2.0 5.3e-26 90.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFP06366.1 - 0.0019 17.4 3.9 0.6 9.2 0.1 3.9 2 2 2 4 4 4 2 Gammaproteobacterial serine protease Arm PF00514.23 KFP06367.1 - 5.8e-10 38.9 1.2 0.085 12.9 0.0 5.7 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 KFP06367.1 - 9.9e-05 22.3 4.4 0.14 12.2 0.2 4.6 3 1 3 6 6 6 2 Spinocerebellar ataxia type 10 protein domain UNC45-central PF11701.8 KFP06367.1 - 0.071 13.1 0.5 0.39 10.6 0.0 2.4 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central Surp PF01805.20 KFP06368.1 - 2.7e-15 56.1 0.1 1.7e-09 37.5 0.1 2.6 2 0 0 2 2 2 2 Surp module G-patch PF01585.23 KFP06368.1 - 2.6e-14 52.8 4.2 5.1e-14 51.9 4.2 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFP06368.1 - 0.0046 17.0 4.9 0.0048 17.0 2.7 2.2 2 0 0 2 2 2 1 G-patch domain DUF2591 PF10765.9 KFP06368.1 - 0.094 13.0 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2591) Nop14 PF04147.12 KFP06368.1 - 0.25 9.5 12.3 0.41 8.8 12.3 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KFP06368.1 - 2.5 6.3 6.3 4 5.6 6.3 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KFP06368.1 - 9.3 5.6 14.9 20 4.5 14.9 1.5 1 0 0 1 1 1 0 SDA1 Sema PF01403.19 KFP06369.1 - 7.8e-145 482.9 0.1 3.2e-144 480.9 0.0 1.8 1 1 1 2 2 2 2 Sema domain PSI PF01437.25 KFP06369.1 - 0.0005 20.6 6.8 0.0005 20.6 6.8 2.1 2 0 0 2 2 2 1 Plexin repeat WH1 PF00568.23 KFP06370.1 - 9e-37 125.4 0.3 1.7e-36 124.5 0.3 1.5 1 0 0 1 1 1 1 WH1 domain GAS PF13851.6 KFP06370.1 - 0.00024 20.5 9.8 0.00024 20.5 9.8 2.9 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding DUF3461 PF11944.8 KFP06370.1 - 1.7 8.8 11.1 0.091 12.9 3.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) Leu_zip PF15294.6 KFP06370.1 - 4.2 6.8 30.1 11 5.4 13.1 3.3 2 1 1 3 3 3 0 Leucine zipper CorA PF01544.18 KFP06370.1 - 5.9 6.1 9.5 12 5.1 9.5 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.12 KFP06370.1 - 7 6.7 16.2 1.5 8.8 2.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) DEAD PF00270.29 KFP06371.1 - 1.8e-29 102.8 1.6 1.3e-28 100.0 0.1 2.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP06371.1 - 1.1e-27 96.5 0.1 3.6e-27 94.9 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFP06371.1 - 0.67 10.2 0.1 0.67 10.2 0.1 2.8 3 0 0 3 3 3 0 AAA domain Coatomer_E PF04733.14 KFP06372.1 - 1.6e-113 378.9 3.8 1.8e-113 378.7 3.8 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 KFP06372.1 - 6.2e-10 39.5 8.1 3.7e-05 24.1 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP06372.1 - 2.8e-09 37.0 9.3 0.0017 19.0 0.0 4.4 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFP06372.1 - 3.8e-07 29.7 5.5 0.00028 20.8 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP06372.1 - 5.7e-07 29.7 0.4 0.043 14.1 0.0 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KFP06372.1 - 2e-06 28.0 0.6 0.00094 19.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFP06372.1 - 4e-05 24.2 3.3 0.0048 17.5 0.0 3.7 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFP06372.1 - 5e-05 23.0 1.5 0.006 16.5 0.0 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFP06372.1 - 0.00011 21.9 4.6 0.0018 18.0 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFP06372.1 - 0.0043 17.6 2.3 1.9 9.3 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat FAT PF02259.23 KFP06372.1 - 0.0068 15.7 1.5 0.011 15.0 1.4 1.3 1 1 0 1 1 1 1 FAT domain CysG_dimeriser PF10414.9 KFP06372.1 - 0.039 13.7 0.1 0.092 12.5 0.1 1.6 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region HemY_N PF07219.13 KFP06372.1 - 0.045 13.9 2.2 7.6 6.8 1.0 2.9 2 1 0 2 2 2 0 HemY protein N-terminus TPR_10 PF13374.6 KFP06372.1 - 0.067 13.1 0.1 0.9 9.5 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFP06372.1 - 0.07 13.8 0.1 22 6.0 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 KFP06372.1 - 0.081 13.2 4.8 7.7 7.0 0.1 3.9 4 0 0 4 4 4 0 PPR repeat Com_YlbF PF06133.11 KFP06372.1 - 0.12 12.9 2.8 1.1 9.9 0.0 2.9 3 0 0 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA PPR_2 PF13041.6 KFP06372.1 - 0.31 11.3 3.6 21 5.4 0.3 3.6 4 0 0 4 4 4 0 PPR repeat family TPR_9 PF13371.6 KFP06372.1 - 1.1 9.4 4.5 39 4.5 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TRAM_LAG1_CLN8 PF03798.16 KFP06373.1 - 1.8e-37 129.0 26.7 2.1e-37 128.8 26.7 1.0 1 0 0 1 1 1 1 TLC domain 2TM PF13239.6 KFP06373.1 - 0.012 15.9 1.5 0.012 15.9 1.5 3.1 3 0 0 3 3 3 0 2TM domain TGF_beta PF00019.20 KFP06375.1 - 2.9e-34 118.2 0.1 5.8e-34 117.2 0.1 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFP06375.1 - 0.00062 19.6 0.4 0.00062 19.6 0.4 1.7 1 1 0 2 2 2 1 TGF-beta propeptide UPF1_Zn_bind PF09416.10 KFP06376.1 - 4.3e-75 250.8 6.7 1.6e-74 249.0 6.9 1.8 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 KFP06376.1 - 5.2e-61 205.8 0.0 8.8e-61 205.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFP06376.1 - 5.2e-48 164.1 2.2 7e-27 94.8 0.3 2.4 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KFP06376.1 - 2.4e-31 107.8 0.0 8.4e-30 102.9 0.0 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KFP06376.1 - 1.5e-13 50.9 0.1 2.3e-12 47.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KFP06376.1 - 1.7e-10 41.4 0.1 6.8e-10 39.5 0.1 2.0 2 1 0 2 2 1 1 AAA domain ResIII PF04851.15 KFP06376.1 - 1.5e-05 25.0 0.0 3.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KFP06376.1 - 0.00013 21.3 0.0 0.0083 15.4 0.0 2.7 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 KFP06376.1 - 0.00048 20.0 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Helicase ATPase PF06745.13 KFP06376.1 - 0.00086 18.7 0.0 0.016 14.6 0.0 2.1 2 0 0 2 2 2 1 KaiC SRP54 PF00448.22 KFP06376.1 - 0.0056 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain UvrD-helicase PF00580.21 KFP06376.1 - 0.021 14.4 0.1 0.9 9.0 0.0 2.7 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 KFP06376.1 - 0.038 13.8 0.0 0.44 10.4 0.0 2.3 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain PIF1 PF05970.14 KFP06376.1 - 0.054 12.7 0.0 5.4 6.1 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase DEAD PF00270.29 KFP06376.1 - 0.11 12.2 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_10 PF12846.7 KFP06376.1 - 0.12 11.2 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain TSP_C PF05735.12 KFP06377.1 - 1.9e-98 328.2 1.0 2.5e-98 327.9 1.0 1.1 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.18 KFP06377.1 - 6.8e-55 182.5 134.2 1e-11 44.3 11.3 9.4 7 2 1 8 8 8 8 Thrombospondin type 3 repeat EGF_CA PF07645.15 KFP06377.1 - 1.3e-18 66.9 43.8 4.7e-09 36.3 7.6 5.6 4 0 0 4 4 4 4 Calcium-binding EGF domain COMP PF11598.8 KFP06377.1 - 4.6e-15 55.8 5.1 1e-14 54.7 5.1 1.6 1 0 0 1 1 1 1 Cartilage oligomeric matrix protein cEGF PF12662.7 KFP06377.1 - 1.1e-11 44.4 26.8 1e-05 25.4 3.5 5.7 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF_3 PF12947.7 KFP06377.1 - 3.6e-08 33.5 50.7 0.00014 22.0 5.2 6.1 6 0 0 6 6 6 4 EGF domain TORC_M PF12885.7 KFP06378.1 - 1.1e-68 230.2 9.0 1.1e-68 230.2 9.0 2.9 3 1 1 4 4 4 1 Transducer of regulated CREB activity middle domain TORC_C PF12886.7 KFP06378.1 - 5.1e-33 113.5 2.3 1.4e-32 112.0 2.3 1.8 1 0 0 1 1 1 1 Transducer of regulated CREB activity, C terminus Kelch_1 PF01344.25 KFP06379.1 - 5.4e-36 121.9 19.2 7.1e-09 35.1 0.4 6.3 5 2 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 KFP06379.1 - 9.9e-35 117.7 2.5 5.1e-06 26.6 0.0 5.6 2 1 3 5 5 5 5 Kelch motif BACK PF07707.15 KFP06379.1 - 9.1e-26 90.0 0.3 1.7e-25 89.1 0.3 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 KFP06379.1 - 9.8e-19 66.5 6.4 0.00015 21.6 0.1 6.1 6 1 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 KFP06379.1 - 4.5e-18 65.0 1.9 0.0014 18.6 0.0 5.5 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP06379.1 - 7.2e-15 54.9 0.3 0.0004 20.6 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain BTB PF00651.31 KFP06379.1 - 3.6e-12 46.5 0.0 7e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.6 KFP06379.1 - 1.7e-10 40.6 6.3 0.085 12.9 0.1 5.3 5 0 0 5 5 5 4 Kelch motif PQQ_3 PF13570.6 KFP06379.1 - 0.041 14.4 0.0 25 5.5 0.1 4.0 4 0 0 4 4 4 0 PQQ-like domain BSMAP PF12280.8 KFP06380.1 - 7.4e-18 65.4 0.0 8.3e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Brain specific membrane anchored protein DUF997 PF06196.12 KFP06380.1 - 0.032 14.2 1.4 0.04 13.9 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF997) TrkA_TMD PF18613.1 KFP06380.1 - 0.05 13.0 5.0 0.074 12.5 5.0 1.3 1 0 0 1 1 1 0 Tyrosine kinase receptor A trans-membrane domain EpoR_lig-bind PF09067.10 KFP06381.1 - 7.4e-14 51.8 0.0 1.1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding IL6Ra-bind PF09240.10 KFP06381.1 - 2.1e-07 31.3 0.1 3.6e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding Lep_receptor_Ig PF06328.11 KFP06381.1 - 3.6e-07 30.0 0.0 2.2e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Ig-like C2-type domain ObR_Ig PF18589.1 KFP06381.1 - 0.00024 21.5 0.6 0.019 15.3 0.6 2.3 1 1 0 1 1 1 1 Obesity receptor immunoglobulin like domain fn3 PF00041.21 KFP06381.1 - 0.052 13.9 0.0 0.095 13.1 0.0 1.4 1 0 0 1 1 1 0 Fibronectin type III domain ubiquitin PF00240.23 KFP06382.1 - 9e-35 118.3 0.3 1.2e-34 117.9 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 KFP06382.1 - 3.3e-33 113.3 12.3 5.2e-33 112.7 12.3 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 KFP06382.1 - 1.7e-17 63.0 0.4 1.7e-17 63.0 0.4 1.4 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFP06382.1 - 1e-05 25.9 0.1 3.8e-05 24.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KFP06382.1 - 0.0021 18.0 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KFP06382.1 - 0.0022 18.1 0.0 0.0047 17.0 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KFP06382.1 - 0.0043 17.4 0.0 0.0077 16.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 KFP06382.1 - 0.014 15.4 0.8 3.3 7.8 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 KFP06382.1 - 0.035 14.6 0.1 0.039 14.5 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain KxDL PF10241.9 KFP06383.1 - 6e-24 84.1 1.3 8.1e-24 83.7 1.3 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein TPR_1 PF00515.28 KFP06384.1 - 1.1e-16 59.8 3.5 3.7e-06 26.5 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat FKBP_C PF00254.28 KFP06384.1 - 2.6e-14 53.3 0.0 4.9e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 KFP06384.1 - 4.3e-14 51.4 3.2 8.6e-06 25.5 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFP06384.1 - 3.7e-09 36.7 0.0 1.2e-05 25.7 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFP06384.1 - 6e-09 35.8 1.6 0.00061 19.8 0.1 2.6 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 KFP06384.1 - 2.4e-08 33.5 0.2 3.3e-05 23.5 0.0 2.8 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.6 KFP06384.1 - 1e-07 31.6 1.6 9.7e-05 22.3 0.0 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFP06384.1 - 3.7e-07 29.7 0.6 0.0047 16.9 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFP06384.1 - 8.2e-07 29.1 0.0 4.8e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFP06384.1 - 1.4e-06 28.8 0.3 0.0004 21.0 0.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFP06384.1 - 4.9e-06 26.7 1.3 0.00046 20.4 0.3 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP06384.1 - 1.6e-05 25.3 0.4 0.011 16.2 0.0 2.5 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFP06384.1 - 2.9e-05 24.1 0.4 0.018 15.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP06384.1 - 7.3e-05 22.9 1.2 0.0011 19.2 0.0 2.8 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 KFP06384.1 - 0.00094 18.2 0.5 0.0012 17.9 0.5 1.1 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 KFP06384.1 - 0.0011 18.7 0.9 1.2 9.1 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat MIT PF04212.18 KFP06384.1 - 0.0031 17.6 1.9 0.61 10.2 0.1 3.0 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 KFP06384.1 - 0.0043 17.6 0.5 0.32 11.7 0.1 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat SPO22 PF08631.10 KFP06384.1 - 0.041 13.4 2.4 0.065 12.7 1.2 1.8 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_20 PF14561.6 KFP06384.1 - 0.079 13.3 0.1 0.29 11.5 0.1 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KFP06384.1 - 0.093 13.2 0.4 2.4 8.6 0.0 2.3 1 1 2 3 3 3 0 Alkyl sulfatase dimerisation ELL PF10390.9 KFP06385.1 - 4.6e-98 328.1 0.0 4.6e-98 328.1 0.0 2.2 2 1 1 3 3 3 1 RNA polymerase II elongation factor ELL Occludin_ELL PF07303.13 KFP06385.1 - 3.9e-34 117.4 13.6 3.9e-34 117.4 13.6 2.9 3 0 0 3 3 3 1 Occludin homology domain Conotoxin PF02950.17 KFP06385.1 - 7.7 7.6 7.3 26 5.9 5.8 2.6 2 0 0 2 2 2 0 Conotoxin NAD_binding_5 PF07994.12 KFP06386.1 - 3.5e-116 388.1 0.0 4.4e-116 387.8 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KFP06386.1 - 1.4e-23 83.2 1.4 1.7e-23 83.0 0.4 1.7 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase Peptidase_C15 PF01470.17 KFP06387.1 - 1.5e-16 61.2 0.0 1.8e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Pyroglutamyl peptidase DUF3060 PF11259.8 KFP06387.1 - 0.019 14.7 0.9 3.6 7.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3060) LSM PF01423.22 KFP06388.1 - 1.4e-12 47.1 0.0 2.1e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 LSM domain bZIP_1 PF00170.21 KFP06389.1 - 8e-18 64.3 17.4 9.1e-18 64.1 17.4 1.0 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KFP06389.1 - 2.9e-10 40.5 8.5 3.6e-10 40.2 8.5 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 KFP06389.1 - 1.4e-08 34.7 16.5 3.2e-08 33.5 16.5 1.6 1 1 0 1 1 1 1 Basic region leucine zipper DUF737 PF05300.11 KFP06389.1 - 0.0026 18.1 4.4 0.0036 17.7 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF737) ZapB PF06005.12 KFP06389.1 - 0.0039 17.6 4.9 0.0039 17.6 4.9 2.0 1 1 0 2 2 2 1 Cell division protein ZapB DUF3450 PF11932.8 KFP06389.1 - 0.0043 16.4 2.1 0.0051 16.1 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Jun PF03957.13 KFP06389.1 - 0.0043 17.0 2.3 0.0043 17.0 2.3 1.5 2 0 0 2 2 2 1 Jun-like transcription factor PspA_IM30 PF04012.12 KFP06389.1 - 0.0051 16.4 4.4 0.0051 16.4 4.4 1.6 1 1 1 2 2 2 1 PspA/IM30 family Jnk-SapK_ap_N PF09744.9 KFP06389.1 - 0.0057 16.9 6.3 0.007 16.6 6.3 1.1 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 TSC22 PF01166.18 KFP06389.1 - 0.02 15.2 2.7 0.027 14.8 1.3 1.8 1 1 1 2 2 2 0 TSC-22/dip/bun family Fib_alpha PF08702.10 KFP06389.1 - 0.027 14.7 3.4 0.035 14.3 3.4 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family NBP1 PF08537.10 KFP06389.1 - 0.048 13.1 4.1 0.06 12.7 4.1 1.2 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 FlaC_arch PF05377.11 KFP06389.1 - 0.049 14.0 2.3 0.055 13.9 1.3 1.5 2 0 0 2 2 1 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 KFP06389.1 - 0.072 13.1 3.8 0.092 12.8 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 KFP06389.1 - 0.079 13.2 5.3 0.1 12.8 5.3 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TEX13 PF15186.6 KFP06389.1 - 0.2 11.3 4.7 0.21 11.2 4.1 1.3 1 1 0 1 1 1 0 Testis-expressed sequence 13 protein family ADIP PF11559.8 KFP06389.1 - 0.2 11.7 9.4 0.3 11.2 9.4 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding KELK PF15796.5 KFP06389.1 - 0.25 11.8 8.6 0.18 12.3 6.9 1.6 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF724 PF05266.14 KFP06389.1 - 0.26 11.1 5.8 0.33 10.7 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) SlyX PF04102.12 KFP06389.1 - 0.71 10.5 4.8 0.49 11.1 1.9 2.0 1 1 1 2 2 2 0 SlyX DivIC PF04977.15 KFP06389.1 - 0.77 9.6 9.0 0.5 10.2 3.4 2.3 1 1 1 2 2 2 0 Septum formation initiator NYD-SP28_assoc PF14775.6 KFP06389.1 - 0.79 9.9 5.5 0.26 11.4 2.2 2.0 2 1 0 2 2 2 0 Sperm tail C-terminal domain DUF4315 PF14193.6 KFP06389.1 - 0.92 9.6 10.2 26 4.9 10.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4315) HMMR_C PF15908.5 KFP06389.1 - 0.95 9.7 8.2 0.32 11.3 1.5 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal YabA PF06156.13 KFP06389.1 - 1 10.0 5.3 4.6 7.9 4.3 1.9 1 1 1 2 2 2 0 Initiation control protein YabA Uso1_p115_C PF04871.13 KFP06389.1 - 2.4 8.5 8.4 0.81 10.1 3.9 1.7 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region PDEase_I PF00233.19 KFP06390.1 - 3.6e-91 305.1 5.7 3.6e-91 305.1 5.7 2.0 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase PDE4_UCR PF18100.1 KFP06390.1 - 8.7e-34 116.7 2.8 8.7e-34 116.7 2.8 2.1 2 0 0 2 2 2 1 Phosphodiesterase 4 upstream conserved regions (UCR) DUF4615 PF15393.6 KFP06390.1 - 0.12 12.9 1.6 0.21 12.2 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4615) Ras PF00071.22 KFP06391.1 - 2.3e-61 206.1 0.8 2.7e-61 205.9 0.8 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP06391.1 - 1.3e-33 115.8 0.5 1.9e-33 115.2 0.5 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP06391.1 - 1.6e-14 53.7 0.1 2.1e-14 53.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFP06391.1 - 6e-06 25.8 0.1 7.3e-05 22.3 0.0 2.0 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFP06391.1 - 0.00016 21.7 0.0 0.00027 21.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP06391.1 - 0.00068 19.2 0.0 0.0027 17.3 0.0 1.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFP06391.1 - 0.00086 18.7 0.1 0.0012 18.3 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KFP06391.1 - 0.016 14.8 0.0 1.7 8.2 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_24 PF13479.6 KFP06391.1 - 0.017 14.8 0.5 0.041 13.6 0.5 1.7 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFP06391.1 - 0.023 14.6 0.1 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KFP06391.1 - 0.028 14.8 0.0 0.11 12.9 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain DUF2757 PF10955.8 KFP06391.1 - 0.029 14.6 0.1 0.06 13.6 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2757) Septin PF00735.18 KFP06391.1 - 0.052 12.8 0.0 0.59 9.4 0.0 2.2 2 0 0 2 2 2 0 Septin G-alpha PF00503.20 KFP06391.1 - 0.066 12.4 0.7 4.5 6.3 0.0 2.8 1 1 1 2 2 2 0 G-protein alpha subunit GILT PF03227.16 KFP06392.1 - 8.2e-21 74.3 0.1 1.3e-20 73.6 0.1 1.2 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) PI3K_P85_iSH2 PF16454.5 KFP06393.1 - 7.5e-61 204.4 21.8 1.1e-60 203.8 21.8 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SH2 PF00017.24 KFP06393.1 - 3.9e-41 139.0 0.1 5.5e-20 71.2 0.0 2.7 2 0 0 2 2 2 2 SH2 domain RhoGAP PF00620.27 KFP06393.1 - 1.6e-25 89.8 1.5 8.7e-25 87.3 0.0 2.5 2 1 1 3 3 3 1 RhoGAP domain SH3_1 PF00018.28 KFP06393.1 - 4.2e-05 23.0 1.1 0.0039 16.8 0.0 3.3 4 0 0 4 4 4 1 SH3 domain SH3_9 PF14604.6 KFP06393.1 - 0.0019 18.0 0.2 0.0064 16.3 0.2 2.0 1 1 0 1 1 1 1 Variant SH3 domain ATG11 PF10377.9 KFP06393.1 - 0.019 15.0 0.9 0.019 15.0 0.9 1.9 2 0 0 2 2 2 0 Autophagy-related protein 11 Mod_r PF07200.13 KFP06393.1 - 1.7 8.8 22.5 0.32 11.1 6.8 2.7 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein BRE1 PF08647.11 KFP06393.1 - 2.3 8.3 15.0 0.1 12.7 6.2 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF1908 PF08926.11 KFP06394.1 - 6.2e-133 442.2 0.6 6.2e-133 442.2 0.6 3.3 4 0 0 4 4 3 1 Domain of unknown function (DUF1908) Pkinase PF00069.25 KFP06394.1 - 1.5e-62 211.4 0.3 4.5e-62 209.8 0.0 1.9 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP06394.1 - 6.6e-27 94.4 0.0 1.6e-26 93.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase PDZ_6 PF17820.1 KFP06394.1 - 2.3e-11 43.3 0.1 5e-11 42.3 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFP06394.1 - 2.4e-08 34.2 0.0 5.2e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP06394.1 - 2.2e-06 27.9 0.0 4.9e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain APH PF01636.23 KFP06394.1 - 8.4e-05 22.6 0.3 0.072 13.0 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KFP06394.1 - 0.00048 19.5 0.0 0.0029 17.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Tricorn_PDZ PF14685.6 KFP06394.1 - 0.0045 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Tricorn protease PDZ domain Haspin_kinase PF12330.8 KFP06394.1 - 0.011 14.8 0.0 0.022 13.7 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KFP06394.1 - 0.031 13.9 0.1 0.031 13.9 0.1 1.8 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 KFP06394.1 - 0.078 11.7 0.0 0.078 11.7 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Arrestin_N PF00339.29 KFP06395.1 - 1.5e-40 138.6 0.0 5.1e-39 133.6 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KFP06395.1 - 1.2e-28 100.2 0.0 4.1e-23 82.3 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 KFP06395.1 - 0.0026 17.0 0.0 0.017 14.3 0.0 2.0 2 0 0 2 2 2 1 Rgp1 Vps26 PF03643.15 KFP06395.1 - 0.0028 16.7 0.0 0.0038 16.3 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Spo0M PF07070.11 KFP06395.1 - 0.47 10.0 1.9 7.7 6.0 0.0 3.0 3 1 0 3 3 3 0 SpoOM protein DUF4601 PF15373.6 KFP06396.1 - 4.6e-56 190.6 15.4 6.1e-56 190.2 15.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4601) PEX11 PF05648.14 KFP06397.1 - 2.5e-32 112.2 0.1 2.7e-32 112.0 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) ATP-synt_I PF03899.15 KFP06397.1 - 0.04 14.3 1.6 0.047 14.1 1.0 1.5 1 1 0 1 1 1 0 ATP synthase I chain OAD_gamma PF04277.13 KFP06397.1 - 0.17 12.5 0.0 0.28 11.8 0.0 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Kelch_1 PF01344.25 KFP06398.1 - 1.8e-47 158.6 9.3 2.5e-12 46.2 0.6 5.7 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 KFP06398.1 - 5.2e-30 103.6 1.3 8.8e-30 102.9 0.7 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFP06398.1 - 6.1e-27 93.0 6.5 9.3e-06 25.8 0.3 5.7 1 1 4 5 5 5 5 Kelch motif BTB PF00651.31 KFP06398.1 - 1.2e-26 93.1 0.2 2.2e-26 92.3 0.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.6 KFP06398.1 - 2.2e-23 82.0 3.9 5.7e-06 26.5 0.0 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.6 KFP06398.1 - 2.3e-21 75.6 1.4 1.8e-06 27.8 0.0 5.8 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP06398.1 - 1.6e-19 69.0 5.6 7.2e-05 22.6 0.2 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 KFP06398.1 - 4.4e-12 45.7 3.9 4.1e-05 23.5 0.0 6.1 6 0 0 6 6 6 2 Kelch motif DUF3342 PF11822.8 KFP06398.1 - 0.00069 19.8 0.0 0.0025 18.0 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) PQQ_3 PF13570.6 KFP06398.1 - 0.017 15.6 4.9 0.71 10.4 0.0 3.4 4 0 0 4 4 2 0 PQQ-like domain HTH_12 PF08461.10 KFP06398.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain PH_16 PF17838.1 KFP06399.1 - 3.4e-41 140.0 0.0 7.6e-41 138.9 0.0 1.6 1 0 0 1 1 1 1 PH domain RhoGEF PF00621.20 KFP06399.1 - 4.2e-33 115.1 3.3 4.2e-33 115.1 3.3 2.6 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 KFP06399.1 - 5.8e-06 26.8 0.0 1.5e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 KFP06399.1 - 0.0016 18.2 0.2 0.0016 18.2 0.2 3.9 3 1 0 3 3 3 1 Pleckstrin homology domain DUF5082 PF16888.5 KFP06399.1 - 0.0029 17.9 7.9 0.0029 17.9 7.9 4.3 3 1 0 4 4 4 1 Domain of unknown function (DUF5082) DNA_pol_A_exoN PF18305.1 KFP06399.1 - 0.04 14.2 0.0 0.16 12.3 0.0 2.0 1 0 0 1 1 1 0 3' to 5' exonuclease C-terminal domain DLP_helical PF18709.1 KFP06400.1 - 0.00046 19.5 5.0 0.0024 17.1 0.4 2.1 2 0 0 2 2 2 2 Dynamin-like helical domain ApoLp-III PF07464.11 KFP06400.1 - 0.0058 16.7 3.7 0.011 15.9 3.7 1.5 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) QWRF PF04484.12 KFP06400.1 - 0.024 14.4 1.0 0.031 14.0 1.0 1.1 1 0 0 1 1 1 0 QWRF family Pro_sub2 PF18513.1 KFP06400.1 - 0.045 13.9 0.0 0.099 12.8 0.0 1.6 1 0 0 1 1 1 0 Prodomain subtilisin 2 Baculo_PEP_C PF04513.12 KFP06400.1 - 0.074 13.1 1.0 0.26 11.3 1.0 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus IZUMO PF15005.6 KFP06400.1 - 0.84 10.1 6.1 1.9 9.0 5.4 2.0 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated RNase_H2-Ydr279 PF09468.10 KFP06400.1 - 0.98 9.6 7.8 26 5.0 7.6 2.5 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain FeoB_Cyto PF17910.1 KFP06400.1 - 1.1 9.9 6.3 7.5 7.2 0.3 2.6 2 0 0 2 2 2 0 FeoB cytosolic helical domain Fib_alpha PF08702.10 KFP06400.1 - 1.2 9.3 6.3 0.24 11.6 1.3 2.1 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family KxDL PF10241.9 KFP06400.1 - 2.5 8.4 11.8 0.31 11.4 2.3 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein TED_complement PF07678.14 KFP06401.1 - 1.1e-106 356.4 0.5 1.9e-106 355.6 0.5 1.4 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_BRD PF07703.14 KFP06401.1 - 1.8e-41 141.8 0.4 5e-39 133.8 0.1 4.0 3 1 0 3 3 3 1 Alpha-2-macroglobulin bait region domain Methyltransf_FA PF12248.8 KFP06401.1 - 1.6e-33 115.1 0.6 4.3e-33 113.7 0.6 1.8 1 0 0 1 1 1 1 Farnesoic acid 0-methyl transferase A2M PF00207.22 KFP06401.1 - 9.2e-31 105.6 3.3 5.2e-30 103.1 0.1 3.6 3 0 0 3 3 3 1 Alpha-2-macroglobulin family A2M_recep PF07677.14 KFP06401.1 - 3e-26 91.9 0.0 8.1e-26 90.6 0.0 1.8 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain MG4 PF17789.1 KFP06401.1 - 1.5e-11 44.3 3.5 5e-11 42.6 0.0 3.4 4 0 0 4 4 3 1 Macroglobulin domain MG4 MG2 PF01835.19 KFP06401.1 - 1.8e-11 44.3 0.0 7.7e-11 42.3 0.0 2.2 1 0 0 1 1 1 1 MG2 domain MG3 PF17791.1 KFP06401.1 - 2.4e-11 43.8 0.0 7.6e-11 42.1 0.0 1.9 1 0 0 1 1 1 1 Macroglobulin domain MG3 Kazal_2 PF07648.15 KFP06401.1 - 4e-07 30.1 6.2 1.3e-06 28.4 6.2 2.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain MG1 PF17790.1 KFP06401.1 - 0.00025 21.4 0.0 0.0016 18.8 0.0 2.5 1 0 0 1 1 1 1 Macroglobulin domain MG1 Rib PF08428.10 KFP06401.1 - 0.0018 18.2 0.5 0.012 15.5 0.1 2.6 2 0 0 2 2 2 1 Rib/alpha-like repeat Kazal_1 PF00050.21 KFP06401.1 - 0.0068 16.4 6.9 0.0068 16.4 6.9 1.9 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain 7tm_1 PF00001.21 KFP06402.1 - 9.8e-45 152.9 20.9 9.8e-45 152.9 20.9 1.7 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP06402.1 - 1.4e-07 31.5 13.4 3e-07 30.4 13.4 1.5 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP06402.1 - 0.19 11.3 18.5 0.4 10.3 18.5 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Sin3a_C PF16879.5 KFP06403.1 - 4.7e-86 289.0 6.3 4.7e-86 289.0 6.3 2.4 2 1 0 2 2 2 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 KFP06403.1 - 5.1e-42 141.9 0.2 5.1e-42 141.9 0.2 2.2 2 0 0 2 2 2 1 Sin3 family co-repressor PAH PF02671.21 KFP06403.1 - 9.4e-42 140.9 9.1 4.7e-17 61.9 0.4 4.5 4 0 0 4 4 4 3 Paired amphipathic helix repeat Pkinase_Tyr PF07714.17 KFP06404.1 - 8.3e-88 294.0 0.9 1.1e-87 293.6 0.9 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP06404.1 - 1.2e-45 156.0 0.3 1.6e-45 155.5 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFP06404.1 - 1.1e-40 137.6 0.2 9e-21 73.8 0.1 2.5 2 0 0 2 2 2 2 SH2 domain Haspin_kinase PF12330.8 KFP06404.1 - 0.00023 20.2 0.2 0.00043 19.3 0.2 1.4 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KFP06404.1 - 0.0015 18.2 2.3 0.0025 17.5 2.3 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KFP06404.1 - 0.04 13.3 0.1 0.067 12.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GrlR PF16518.5 KFP06404.1 - 0.093 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 T3SS negative regulator,GrlR Pep_M12B_propep PF01562.19 KFP06405.1 - 1.4e-37 129.1 0.1 2.2e-37 128.4 0.1 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_spacer1 PF05986.14 KFP06405.1 - 8.7e-32 109.5 0.0 1.4e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.19 KFP06405.1 - 3.8e-19 68.6 81.1 5.5e-07 29.7 8.2 7.4 7 0 0 7 7 7 5 Thrombospondin type 1 domain ADAM_CR_2 PF17771.1 KFP06405.1 - 1.5e-17 63.8 9.1 1.5e-17 63.8 9.1 5.5 5 1 0 5 5 5 2 ADAM cysteine-rich domain Reprolysin PF01421.19 KFP06405.1 - 5.8e-12 45.9 0.4 6.4e-11 42.5 0.4 2.4 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease PLAC PF08686.11 KFP06405.1 - 3.5e-09 37.2 11.6 1.6e-08 35.1 11.6 2.3 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Myosin_head PF00063.21 KFP06406.1 - 3e-252 838.7 2.2 3.7e-252 838.4 2.2 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KFP06406.1 - 6e-50 169.5 0.2 1.4e-49 168.3 0.2 1.6 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_9 PF14604.6 KFP06406.1 - 8.3e-15 54.4 0.0 8.5e-14 51.2 0.1 2.7 3 0 0 3 3 3 1 Variant SH3 domain SH3_1 PF00018.28 KFP06406.1 - 2.9e-13 49.2 0.4 1.1e-12 47.3 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFP06406.1 - 1.6e-11 43.7 0.1 3.5e-11 42.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain AAA_16 PF13191.6 KFP06406.1 - 0.014 15.8 0.0 0.046 14.1 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 KFP06406.1 - 0.058 13.3 0.1 0.2 11.6 0.1 1.9 1 0 0 1 1 1 0 Microtubule binding ABC_tran PF00005.27 KFP06406.1 - 0.058 13.9 0.0 0.21 12.1 0.0 2.0 1 0 0 1 1 1 0 ABC transporter DUF2158 PF09926.9 KFP06406.1 - 0.063 13.0 0.3 0.15 11.8 0.3 1.6 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) IQ PF00612.27 KFP06406.1 - 0.081 12.8 1.2 0.25 11.2 1.2 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF2075 PF09848.9 KFP06406.1 - 0.081 12.1 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KFP06406.1 - 0.088 13.1 0.1 0.29 11.4 0.1 1.8 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 KFP06406.1 - 0.16 11.5 0.4 9.2 5.8 0.1 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain ATP_bind_2 PF03668.15 KFP06406.1 - 0.17 11.2 0.5 0.56 9.4 0.2 2.0 2 0 0 2 2 2 0 P-loop ATPase protein family LRR_9 PF14580.6 KFP06407.1 - 3.3e-16 59.3 1.0 4.7e-16 58.8 1.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KFP06407.1 - 1e-09 38.5 19.9 5.2e-08 33.1 6.6 3.2 1 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFP06407.1 - 2.8e-06 26.9 5.5 0.015 15.3 0.2 4.0 3 0 0 3 3 3 2 Leucine Rich repeat LRR_8 PF13855.6 KFP06407.1 - 9.5e-06 25.3 11.2 1.1e-05 25.1 5.8 3.2 1 1 2 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 KFP06407.1 - 0.0015 18.8 8.8 0.98 10.2 0.3 4.5 4 0 0 4 4 4 1 Leucine Rich Repeat SDA1 PF05285.12 KFP06407.1 - 0.38 10.1 31.6 0.48 9.8 31.6 1.2 1 0 0 1 1 1 0 SDA1 Ceramidase PF05875.12 KFP06408.1 - 1.3e-55 188.7 17.1 1.4e-55 188.6 17.1 1.0 1 0 0 1 1 1 1 Ceramidase TMEM173 PF15009.6 KFP06408.1 - 1.6 7.9 7.9 0.39 9.8 2.8 1.9 1 1 1 2 2 2 0 Transmembrane protein 173 DUF373 PF04123.13 KFP06408.1 - 2.3 7.6 3.6 6.5 6.1 3.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF373) DUF2070 PF09843.9 KFP06408.1 - 5 5.3 7.3 6 5.0 7.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) AMP-binding PF00501.28 KFP06409.1 - 1.3e-87 294.1 0.0 1.6e-87 293.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Carla_C4 PF01623.17 KFP06409.1 - 0.048 13.6 2.0 0.12 12.3 2.0 1.6 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein Peptidase_C1 PF00112.23 KFP06410.1 - 5.1e-53 180.4 0.2 8e-53 179.7 0.2 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KFP06410.1 - 3e-15 56.4 0.9 4.8e-15 55.7 0.9 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KFP06410.1 - 0.057 12.2 0.2 0.1 11.4 0.2 1.3 1 0 0 1 1 1 0 Peptidase C1-like family PTPlike_phytase PF14566.6 KFP06410.1 - 0.079 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate UPF0556 PF10572.9 KFP06411.1 - 2.6e-80 267.3 0.0 3e-80 267.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0556 DUF758 PF05527.11 KFP06412.1 - 3.3e-76 255.3 2.2 3.7e-76 255.2 2.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) RPAP3_C PF13877.6 KFP06412.1 - 0.018 15.6 0.5 0.038 14.5 0.3 1.6 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 Pico_P2B PF01552.17 KFP06412.1 - 0.096 12.9 0.1 0.21 11.8 0.1 1.7 1 0 0 1 1 1 0 Picornavirus 2B protein DEP PF00610.21 KFP06412.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) SGP PF17228.2 KFP06413.1 - 0.0013 19.5 8.9 0.058 14.2 8.9 2.1 1 1 0 1 1 1 1 Sulphur globule protein Thioredoxin_6 PF13848.6 KFP06414.1 - 3.6e-23 82.4 0.0 2.9e-21 76.2 0.0 3.1 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin PF00085.20 KFP06414.1 - 4.6e-10 39.4 0.0 2.2e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin E7 PF00527.18 KFP06414.1 - 4.8 7.4 7.3 12 6.2 7.3 1.6 1 0 0 1 1 1 0 E7 protein, Early protein FAM150 PF15129.6 KFP06414.1 - 5.8 7.1 5.1 12 6.1 5.1 1.4 1 0 0 1 1 1 0 FAM150 family CDC45 PF02724.14 KFP06414.1 - 6.8 4.8 7.2 10 4.3 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1084 PF06454.11 KFP06415.1 - 0.061 12.7 13.1 0.24 10.7 13.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1084) DUF389 PF04087.14 KFP06415.1 - 0.4 10.7 5.1 0.17 11.9 1.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF389) AAA PF00004.29 KFP06416.1 - 8e-44 149.3 0.0 1.6e-43 148.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFP06416.1 - 7.2e-12 44.9 0.1 1.7e-11 43.7 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KFP06416.1 - 8.4e-10 38.5 0.6 1.6e-09 37.6 0.0 1.7 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 KFP06416.1 - 5.4e-07 30.1 0.2 0.00062 20.2 0.1 2.9 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KFP06416.1 - 5.5e-06 26.4 0.2 0.00014 21.9 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFP06416.1 - 7.7e-06 26.1 0.0 8.8e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFP06416.1 - 7.8e-06 26.2 0.8 0.0033 17.7 0.0 2.9 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 KFP06416.1 - 2.2e-05 24.3 0.0 5.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KFP06416.1 - 0.00041 20.9 0.0 0.0025 18.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Prot_ATP_OB_N PF17758.1 KFP06416.1 - 0.00065 19.3 0.2 0.0022 17.6 0.0 1.8 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_33 PF13671.6 KFP06416.1 - 0.0014 18.8 0.0 0.0035 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KFP06416.1 - 0.0036 16.8 0.0 0.007 15.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 KFP06416.1 - 0.0039 16.4 0.0 0.014 14.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_3 PF07726.11 KFP06416.1 - 0.0069 16.3 0.0 0.026 14.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KFP06416.1 - 0.0076 16.3 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KFP06416.1 - 0.0081 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KFP06416.1 - 0.0082 15.9 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KFP06416.1 - 0.0099 16.3 0.0 0.024 15.0 0.0 1.7 1 0 0 1 1 1 1 RNA helicase Thymidylate_kin PF02223.17 KFP06416.1 - 0.011 15.4 0.0 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase TIP49 PF06068.13 KFP06416.1 - 0.011 14.9 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 KFP06416.1 - 0.013 14.9 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 KFP06416.1 - 0.014 15.2 0.2 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain TPR_MLP1_2 PF07926.12 KFP06416.1 - 0.015 15.3 1.1 0.029 14.4 1.1 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA_24 PF13479.6 KFP06416.1 - 0.021 14.5 0.0 0.069 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain GAS PF13851.6 KFP06416.1 - 0.038 13.3 4.5 0.065 12.6 4.5 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ATPase PF06745.13 KFP06416.1 - 0.047 13.0 0.1 0.58 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC NACHT PF05729.12 KFP06416.1 - 0.057 13.3 0.0 0.2 11.5 0.0 1.9 1 1 1 2 2 2 0 NACHT domain AAA_25 PF13481.6 KFP06416.1 - 0.065 12.8 0.0 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KFP06416.1 - 0.13 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Syntaxin-6_N PF09177.11 KFP06416.1 - 0.14 12.7 0.4 2 9.0 0.2 2.6 3 0 0 3 3 2 0 Syntaxin 6, N-terminal Med4 PF10018.9 KFP06416.1 - 0.19 11.4 3.0 0.39 10.4 3.0 1.4 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF4140 PF13600.6 KFP06416.1 - 0.21 12.1 0.7 0.69 10.4 0.8 1.9 2 0 0 2 2 1 0 N-terminal domain of unknown function (DUF4140) AAA_23 PF13476.6 KFP06416.1 - 0.29 11.6 4.4 24 5.3 5.4 2.3 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 KFP06416.1 - 0.45 9.1 1.9 15 4.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Acetyltransf_1 PF00583.25 KFP06417.1 - 2.5e-10 40.6 0.0 3.2e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFP06417.1 - 6.7e-08 32.5 0.0 9e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFP06417.1 - 2.2e-07 31.2 0.0 3.1e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFP06417.1 - 0.12 12.5 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FERM_M PF00373.18 KFP06418.1 - 1.8e-47 160.6 0.0 8.8e-47 158.4 0.0 2.2 1 1 0 1 1 1 1 FERM central domain Kindlin_2_N PF18124.1 KFP06418.1 - 9.9e-20 70.5 7.6 3.1e-19 69.0 7.6 1.9 1 0 0 1 1 1 1 Kindlin-2 N-terminal domain PH PF00169.29 KFP06418.1 - 1e-09 38.8 0.1 2.7e-09 37.5 0.1 1.7 1 0 0 1 1 1 1 PH domain FERM_N PF09379.10 KFP06418.1 - 0.0016 18.4 0.0 0.0051 16.7 0.0 1.9 1 1 0 1 1 1 1 FERM N-terminal domain DDHD PF02862.17 KFP06419.1 - 8.3e-49 166.7 0.1 3.3e-48 164.8 0.1 2.0 1 1 0 1 1 1 1 DDHD domain DUF676 PF05057.14 KFP06419.1 - 0.063 12.8 1.2 4.4 6.8 0.1 2.3 1 1 1 2 2 2 0 Putative serine esterase (DUF676) TGFb_propeptide PF00688.18 KFP06420.1 - 3.5e-54 184.2 0.6 4.8e-54 183.7 0.6 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 KFP06420.1 - 6.6e-34 117.0 0.5 1.4e-33 116.0 0.5 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain Tnp_DNA_bind PF14706.6 KFP06420.1 - 0.055 13.3 0.0 2.1 8.3 0.0 2.6 2 0 0 2 2 2 0 Transposase DNA-binding CDKN3 PF05706.12 KFP06421.1 - 1.1e-71 239.9 1.4 1.3e-71 239.7 1.4 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 KFP06421.1 - 3.4e-07 30.1 0.0 4.2e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFP06421.1 - 2.4e-05 24.2 0.0 3.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFP06421.1 - 0.079 13.1 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate ANF_receptor PF01094.28 KFP06421.1 - 0.15 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region zf-C3HC4_3 PF13920.6 KFP06422.1 - 1.9e-11 43.6 11.5 4.7e-11 42.4 11.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP06422.1 - 0.00026 20.8 10.8 0.00084 19.1 10.8 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 SAM_1 PF00536.30 KFP06423.1 - 8.1e-09 35.8 0.1 1.5e-08 34.9 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PHAT PF09246.10 KFP06423.1 - 0.00012 21.8 0.1 0.077 12.8 0.0 3.0 3 0 0 3 3 3 2 PHAT SAM_2 PF07647.17 KFP06423.1 - 0.013 15.6 0.0 0.035 14.2 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Sde2_N_Ubi PF13019.6 KFP06423.1 - 0.015 15.1 0.0 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain GTP_cyclohydroI PF01227.22 KFP06424.1 - 2.1e-77 258.6 0.2 2.3e-77 258.4 0.2 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KFP06424.1 - 0.00061 19.9 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein MAPKK1_Int PF08923.10 KFP06424.1 - 0.036 13.9 0.2 0.049 13.4 0.2 1.2 1 0 0 1 1 1 0 Mitogen-activated protein kinase kinase 1 interacting Mcl1_mid PF12341.8 KFP06425.1 - 2e-92 309.7 0.0 4.6e-92 308.5 0.0 1.6 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KFP06425.1 - 2.1e-20 72.7 13.2 2.3e-07 31.4 0.1 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP06425.1 - 9e-11 41.9 0.6 2.3e-05 24.6 0.1 3.9 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain HMG_box PF00505.19 KFP06425.1 - 3.8e-07 30.4 0.0 9.4e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box eIF2A PF08662.11 KFP06425.1 - 3.1e-06 27.2 0.1 0.0001 22.3 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KFP06425.1 - 0.0022 16.7 0.1 0.3 9.7 0.0 2.2 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Hira PF07569.11 KFP06425.1 - 0.0063 16.3 0.4 1.3 8.7 0.0 2.8 2 0 0 2 2 2 1 TUP1-like enhancer of split HMG_box_2 PF09011.10 KFP06425.1 - 0.0068 17.0 0.0 0.027 15.1 0.0 2.0 1 0 0 1 1 1 1 HMG-box domain Ge1_WD40 PF16529.5 KFP06425.1 - 0.1 11.6 1.1 36 3.2 0.0 3.5 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SOCS PF12610.8 KFP06426.1 - 1.9e-19 69.8 3.0 6.7e-19 68.0 3.0 1.9 1 0 0 1 1 1 1 Suppressor of cytokine signalling SOCS_box PF07525.16 KFP06426.1 - 1.2e-10 41.5 0.1 2.4e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 SOCS box SH2 PF00017.24 KFP06426.1 - 3.1e-08 33.6 0.0 7.7e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 SH2 domain MISS PF15822.5 KFP06427.1 - 9.6e-97 323.5 120.1 1.1e-96 323.3 120.1 1.0 1 0 0 1 1 1 1 MAPK-interacting and spindle-stabilising protein-like Gal-bind_lectin PF00337.22 KFP06428.1 - 3.5e-36 123.7 0.0 4.4e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Galactoside-binding lectin GKAP PF03359.13 KFP06429.1 - 0.0012 18.5 0.2 0.0012 18.5 0.2 2.4 2 0 0 2 2 2 1 Guanylate-kinase-associated protein (GKAP) protein RR_TM4-6 PF06459.12 KFP06429.1 - 1.9 8.3 7.1 4.1 7.1 7.1 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 F-box-like PF12937.7 KFP06430.1 - 5.6e-05 23.0 0.0 0.00015 21.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like BTK PF00779.19 KFP06430.1 - 0.0025 17.6 1.2 0.0025 17.6 1.2 1.9 2 0 0 2 2 2 1 BTK motif F-box PF00646.33 KFP06430.1 - 0.0077 16.1 0.0 0.025 14.5 0.0 1.8 1 0 0 1 1 1 1 F-box domain Atg14 PF10186.9 KFP06431.1 - 1.6e-62 211.4 6.8 2e-62 211.1 6.8 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 UL141 PF16758.5 KFP06431.1 - 0.095 12.4 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Herpes-like virus membrane glycoprotein UL141 MscS_TM PF12794.7 KFP06431.1 - 0.24 10.2 1.4 7.1 5.4 0.0 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Exonuc_VII_L PF02601.15 KFP06431.1 - 0.26 10.8 10.6 0.42 10.1 10.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit SpecificRecomb PF10136.9 KFP06431.1 - 1.7 6.9 3.7 2.3 6.4 3.7 1.1 1 0 0 1 1 1 0 Site-specific recombinase TBP PF00352.21 KFP06432.1 - 9.6e-57 188.9 0.4 1.6e-32 111.3 0.1 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KFP06432.1 - 0.00021 21.3 0.0 0.43 10.7 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Pellino PF04710.14 KFP06434.1 - 2.8e-218 724.5 0.1 3.2e-218 724.4 0.1 1.0 1 0 0 1 1 1 1 Pellino Prok-RING_4 PF14447.6 KFP06434.1 - 0.0052 16.6 8.2 1.5 8.7 3.9 3.5 2 1 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFP06434.1 - 0.009 15.9 8.8 0.35 10.8 0.9 3.3 2 2 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP06434.1 - 0.55 10.2 0.1 0.55 10.2 0.1 3.6 3 1 1 4 4 4 0 zinc-RING finger domain zf-RING_2 PF13639.6 KFP06434.1 - 1.2 9.5 13.2 0.64 10.4 0.5 3.2 3 1 0 3 3 3 0 Ring finger domain DUF2723 PF11028.8 KFP06435.1 - 3e-36 124.9 4.8 3e-36 124.9 4.8 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF2723) TF_Otx PF03529.13 KFP06436.1 - 2.9e-33 114.1 14.8 2.9e-33 114.1 14.8 2.7 2 1 1 3 3 3 1 Otx1 transcription factor Sec10 PF07393.11 KFP06437.1 - 3e-152 508.6 29.9 2.6e-150 502.2 22.1 3.5 2 1 0 2 2 2 1 Exocyst complex component Sec10 V_ATPase_I PF01496.19 KFP06437.1 - 0.4 8.5 16.5 0.039 11.9 11.9 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Phasin PF05597.11 KFP06437.1 - 2.2 8.3 7.7 1.7 8.6 0.9 3.5 4 0 0 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Jnk-SapK_ap_N PF09744.9 KFP06437.1 - 2.6 8.2 18.2 0.059 13.6 9.4 2.7 3 1 0 3 3 3 0 JNK_SAPK-associated protein-1 EF-G-binding_N PF07299.11 KFP06437.1 - 3.2 8.3 10.0 4.4 7.9 2.9 3.6 2 1 0 2 2 2 0 Elongation factor G-binding protein, N-terminal Cnn_1N PF07989.11 KFP06437.1 - 6.3 7.0 12.7 5.2 7.3 1.2 3.2 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 BLOC1_2 PF10046.9 KFP06437.1 - 6.4 7.2 10.8 0.17 12.2 2.7 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2203 PF09969.9 KFP06437.1 - 8.5 7.1 7.7 2.9 8.6 1.2 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Acetyltransf_1 PF00583.25 KFP06438.1 - 8.7e-18 64.7 0.0 1.4e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFP06438.1 - 4.7e-12 46.0 0.0 7.6e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFP06438.1 - 5.9e-12 45.8 0.0 9.8e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFP06438.1 - 4.9e-09 36.0 0.0 9e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KFP06438.1 - 4.9e-05 23.0 0.0 9.5e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KFP06438.1 - 0.00012 22.8 0.0 0.00018 22.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFP06438.1 - 0.0012 18.9 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SUIM_assoc PF16619.5 KFP06438.1 - 0.096 12.8 7.5 0.21 11.7 7.5 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TGS PF02824.21 KFP06438.1 - 0.14 12.2 0.0 0.37 10.9 0.0 1.7 2 0 0 2 2 2 0 TGS domain PRR18 PF15671.5 KFP06438.1 - 2.2 8.1 7.5 2.9 7.7 7.2 1.4 1 1 0 1 1 1 0 Proline-rich protein family 18 DUF4619 PF15398.6 KFP06439.1 - 5.5e-93 311.7 1.3 6.2e-93 311.6 1.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4619) HrpB4 PF09502.10 KFP06439.1 - 0.025 14.4 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB4) SLC35F PF06027.12 KFP06440.1 - 1.7e-05 24.5 11.3 2.6e-05 23.9 11.3 1.4 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 KFP06440.1 - 2.8e-05 24.3 12.1 2.8e-05 24.3 12.1 3.1 2 2 0 2 2 2 1 EamA-like transporter family DUF4696 PF15767.5 KFP06441.1 - 1.1e-125 420.5 58.7 1.8e-125 419.8 58.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4696) BUD22 PF09073.10 KFP06441.1 - 0.0051 16.2 1.9 0.0086 15.5 1.9 1.4 1 0 0 1 1 1 1 BUD22 Drc1-Sld2 PF11719.8 KFP06441.1 - 0.0066 16.1 2.9 0.011 15.3 2.9 1.4 1 0 0 1 1 1 1 DNA replication and checkpoint protein SDA1 PF05285.12 KFP06441.1 - 0.016 14.6 5.5 0.028 13.9 5.5 1.3 1 0 0 1 1 1 0 SDA1 TRAP_alpha PF03896.16 KFP06441.1 - 0.066 12.4 3.0 0.14 11.4 3.0 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.12 KFP06441.1 - 0.092 11.0 10.2 0.14 10.4 10.2 1.1 1 0 0 1 1 1 0 Nop14-like family Plasmodium_Vir PF05795.11 KFP06441.1 - 0.14 11.5 0.0 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 Plasmodium vivax Vir protein FAM176 PF14851.6 KFP06441.1 - 0.18 11.5 7.1 2.6 7.7 7.9 2.2 2 0 0 2 2 2 0 FAM176 family VID27_N PF17748.1 KFP06441.1 - 0.35 10.7 4.8 0.59 10.0 4.8 1.3 1 0 0 1 1 1 0 VID27 N-terminal region DUF4611 PF15387.6 KFP06441.1 - 0.47 10.7 15.2 0.031 14.5 8.9 2.3 3 0 0 3 3 2 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 KFP06441.1 - 0.58 8.2 16.0 0.85 7.6 16.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 KFP06441.1 - 0.64 10.0 5.1 1.5 8.8 5.1 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal Paf1 PF03985.13 KFP06441.1 - 0.65 8.9 9.8 1.2 8.0 9.8 1.3 1 0 0 1 1 1 0 Paf1 RNA_pol_3_Rpc31 PF11705.8 KFP06441.1 - 0.92 9.7 15.4 2.3 8.4 15.4 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Sigma70_ner PF04546.13 KFP06441.1 - 1.6 8.6 10.1 2.8 7.8 10.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region BSP_II PF05432.11 KFP06441.1 - 3.4 7.3 17.9 0.048 13.4 9.6 2.1 2 0 0 2 2 1 0 Bone sialoprotein II (BSP-II) HSP90 PF00183.18 KFP06441.1 - 4.8 6.0 7.2 7.3 5.4 7.2 1.1 1 0 0 1 1 1 0 Hsp90 protein DUF4746 PF15928.5 KFP06441.1 - 5.4 6.4 9.7 11 5.4 9.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RRN3 PF05327.11 KFP06441.1 - 6.4 5.2 8.2 9.5 4.6 8.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFB6 PF17110.5 KFP06441.1 - 7 6.4 8.0 14 5.4 8.0 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH NOA36 PF06524.12 KFP06441.1 - 9.9 5.4 12.8 15 4.8 12.8 1.2 1 0 0 1 1 1 0 NOA36 protein Actin PF00022.19 KFP06442.1 - 6.5e-51 173.2 0.0 1.3e-48 165.6 0.0 2.5 1 1 0 1 1 1 1 Actin Proteasome PF00227.26 KFP06443.1 - 1.2e-50 171.7 0.2 1.4e-50 171.5 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFP06443.1 - 1.5e-14 53.3 0.1 2.6e-14 52.6 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RBB1NT PF08169.11 KFP06444.1 - 2.1e-24 85.5 0.6 2.1e-24 85.5 0.6 2.5 2 0 0 2 2 2 1 RBB1NT (NUC162) domain ARID PF01388.21 KFP06444.1 - 1.2e-17 64.3 0.0 3.1e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Tudor-knot PF11717.8 KFP06444.1 - 2.6e-13 49.6 2.0 8.2e-13 48.0 2.0 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain RVT_1 PF00078.27 KFP06444.1 - 0.042 13.4 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-Tim10_DDP PF02953.15 KFP06445.1 - 2.2e-17 62.4 4.6 2.9e-17 62.1 4.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2116 PF09889.9 KFP06445.1 - 0.021 14.8 1.0 0.027 14.4 0.5 1.4 1 1 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) TALPID3 PF15324.6 KFP06446.1 - 0 1573.0 79.7 0 1344.6 50.8 2.1 1 1 1 2 2 2 2 Hedgehog signalling target DinB_2 PF12867.7 KFP06446.1 - 0.013 16.0 0.3 2.6 8.6 0.0 3.1 3 0 0 3 3 3 0 DinB superfamily Synaptonemal_3 PF15191.6 KFP06446.1 - 0.057 13.2 5.1 1.8 8.4 0.5 3.5 2 1 1 3 3 3 0 Synaptonemal complex central element protein 3 Syntaxin-6_N PF09177.11 KFP06446.1 - 6.4 7.4 10.8 6.4 7.4 4.5 3.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Dapper PF15268.6 KFP06447.1 - 2.7e-177 592.2 36.1 4e-135 452.7 30.6 2.9 1 1 1 2 2 2 2 Dapper Ion_trans_2 PF07885.16 KFP06448.1 - 2.2e-33 114.1 17.7 1.1e-17 63.7 0.2 2.9 3 0 0 3 3 3 2 Ion channel DUF2070 PF09843.9 KFP06448.1 - 0.086 11.1 0.0 0.086 11.1 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) IclR PF01614.18 KFP06448.1 - 0.18 11.6 0.4 0.43 10.4 0.1 1.7 2 0 0 2 2 2 0 Bacterial transcriptional regulator Mab-21 PF03281.14 KFP06449.1 - 3.2e-09 36.5 1.8 1.4e-07 31.1 1.9 2.2 1 1 0 1 1 1 1 Mab-21 protein FH2 PF02181.23 KFP06450.1 - 1e-105 353.9 12.7 1e-105 353.9 12.7 2.7 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 KFP06450.1 - 3.1e-62 209.7 2.1 3.1e-62 209.7 2.1 2.6 3 0 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 KFP06450.1 - 9.1e-48 162.3 0.7 9.1e-48 162.3 0.7 3.4 4 0 0 4 4 4 1 Diaphanous GTPase-binding Domain TPR_MLP1_2 PF07926.12 KFP06450.1 - 0.006 16.6 0.0 0.006 16.6 0.0 4.8 5 0 0 5 5 5 1 TPR/MLP1/MLP2-like protein Fe_bilin_red PF05996.12 KFP06450.1 - 0.043 13.5 3.0 0.17 11.5 3.0 2.0 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase Herpes_teg_N PF04843.12 KFP06450.1 - 0.047 13.4 0.0 0.15 11.7 0.0 1.9 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region Ribosomal_S2 PF00318.20 KFP06450.1 - 4.4 6.5 8.3 0.11 11.7 0.2 2.3 2 0 0 2 2 2 0 Ribosomal protein S2 Totivirus_coat PF05518.11 KFP06450.1 - 7.9 4.4 5.4 12 3.8 5.4 1.2 1 0 0 1 1 1 0 Totivirus coat protein Pro_racemase PF05544.11 KFP06451.1 - 8.8e-57 192.6 0.1 9.9e-57 192.4 0.1 1.0 1 0 0 1 1 1 1 Proline racemase JAMP PF05571.12 KFP06452.1 - 5.3e-72 242.9 11.9 7.1e-71 239.2 11.9 1.9 1 1 0 1 1 1 1 JNK1/MAPK8-associated membrane protein FAM35_C PF15793.5 KFP06452.1 - 1.3 8.4 4.4 0.35 10.2 0.5 1.8 2 0 0 2 2 2 0 Protein family FAM35, C-terminal PSP1 PF04468.12 KFP06453.1 - 0.32 11.3 6.4 0.33 11.3 1.4 2.8 1 1 1 2 2 2 0 PSP1 C-terminal conserved region DUF4715 PF15835.5 KFP06453.1 - 0.36 10.9 11.5 0.11 12.6 1.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4715) Hema_stalk PF08720.10 KFP06453.1 - 0.52 10.0 2.2 0.35 10.5 0.4 1.6 2 0 0 2 2 2 0 Influenza C hemagglutinin stalk TPR_MLP1_2 PF07926.12 KFP06453.1 - 0.9 9.6 31.1 0.053 13.6 5.9 3.4 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Bacillus_HBL PF05791.11 KFP06453.1 - 7.7 6.3 13.4 0.084 12.7 2.1 2.7 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) AKNA PF12443.8 KFP06454.1 - 0.0063 17.1 3.2 0.0065 17.1 1.7 1.9 1 1 0 2 2 2 1 AT-hook-containing transcription factor DEAD_assoc PF08494.11 KFP06454.1 - 0.042 13.6 1.7 0.052 13.3 1.3 1.3 1 1 0 1 1 1 0 DEAD/H associated GvpO PF05800.11 KFP06454.1 - 0.34 10.9 4.0 0.25 11.4 1.1 2.1 1 1 0 2 2 2 0 Gas vesicle synthesis protein GvpO COG2 PF06148.11 KFP06454.1 - 2.1 8.4 7.9 2.7 8.1 4.3 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Atg14 PF10186.9 KFP06454.1 - 3.7 6.5 14.8 4.8 6.2 14.8 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 KfrA_N PF11740.8 KFP06454.1 - 9.1 7.0 15.8 13 6.5 5.2 2.5 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Reticulon PF02453.17 KFP06455.1 - 9.9e-47 158.8 7.6 1.4e-46 158.3 7.6 1.2 1 0 0 1 1 1 1 Reticulon DUF4736 PF15883.5 KFP06455.1 - 0.043 13.5 0.2 0.043 13.5 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) Pecanex_C PF05041.15 KFP06457.1 - 1.3e-25 90.4 0.0 2.1e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Pecanex protein (C-terminus) YoqO PF14037.6 KFP06457.1 - 0.25 11.9 4.9 11 6.6 0.9 3.1 2 0 0 2 2 2 0 YoqO-like protein adh_short PF00106.25 KFP06458.1 - 2.4e-53 180.5 0.0 2.8e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP06458.1 - 1.9e-32 112.7 0.0 2.3e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP06458.1 - 1.5e-12 47.8 0.1 2e-12 47.4 0.1 1.1 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 KFP06458.1 - 0.0016 17.8 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3341 PF11821.8 KFP06458.1 - 0.069 12.8 0.1 13 5.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) PP2C PF00481.21 KFP06459.1 - 9.4e-88 294.2 0.0 1.2e-87 293.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.13 KFP06459.1 - 1.2e-32 112.2 0.1 2.3e-32 111.3 0.1 1.5 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain S6OS1 PF15676.5 KFP06460.1 - 3.2e-224 745.6 39.5 3.5e-224 745.4 39.5 1.0 1 0 0 1 1 1 1 Six6 opposite strand transcript 1 family LemA PF04011.12 KFP06460.1 - 0.013 15.4 16.9 0.75 9.6 0.4 3.1 2 1 1 3 3 3 0 LemA family Fib_alpha PF08702.10 KFP06460.1 - 0.063 13.5 24.0 0.1 12.8 0.7 3.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 KFP06460.1 - 0.46 9.8 16.8 0.47 9.7 9.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF3452 PF11934.8 KFP06460.1 - 1.3 8.6 10.1 3.4 7.2 2.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3452) ANAPC4 PF12896.7 KFP06460.1 - 2.7 7.4 9.2 0.61 9.5 2.0 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 SIX1_SD PF16878.5 KFP06461.1 - 3.1e-48 162.9 0.0 3.6e-48 162.7 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator, SIX1, N-terminal SD domain SIX1_SD PF16878.5 KFP06462.1 - 2.3e-49 166.6 0.1 4.1e-49 165.7 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 KFP06462.1 - 1.2e-14 53.9 1.3 2.7e-14 52.7 0.2 2.1 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KFP06462.1 - 7.1e-13 48.2 1.1 1.5e-12 47.2 1.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 KFP06462.1 - 0.0037 16.7 0.1 0.015 14.7 0.1 2.0 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez HTH_3 PF01381.22 KFP06462.1 - 0.0082 16.2 0.0 0.03 14.4 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix YdaS_antitoxin PF15943.5 KFP06462.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Phage_mat-A PF03863.13 KFP06462.1 - 0.14 11.1 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Phage maturation protein KilA-N PF04383.13 KFP06462.1 - 0.17 11.7 0.3 1.3 8.9 0.1 2.0 2 0 0 2 2 2 0 KilA-N domain SIX1_SD PF16878.5 KFP06463.1 - 1.1e-45 154.6 0.6 2.4e-44 150.4 0.0 2.7 3 0 0 3 3 3 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 KFP06463.1 - 3e-13 49.4 1.2 6.7e-13 48.3 1.2 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP06463.1 - 2.6e-08 33.6 0.5 6.9e-08 32.3 0.5 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 KFP06463.1 - 0.15 11.6 0.0 0.34 10.4 0.0 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez MAT1 PF06391.13 KFP06464.1 - 3.6e-65 219.6 20.3 4.1e-65 219.4 20.3 1.0 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 AAA_23 PF13476.6 KFP06464.1 - 0.12 12.9 10.1 0.15 12.5 10.1 1.3 1 0 0 1 1 1 0 AAA domain EbsA PF17255.2 KFP06464.1 - 0.32 11.3 5.9 0.38 11.1 4.2 1.9 1 1 1 2 2 2 0 EbsA-like protein ESM4 PF15952.5 KFP06464.1 - 0.38 11.2 7.9 0.63 10.4 7.9 1.3 1 0 0 1 1 1 0 Enhancer of split M4 family Activator_LAG-3 PF11498.8 KFP06464.1 - 1.2 8.0 10.9 1.6 7.6 10.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Met_10 PF02475.16 KFP06465.1 - 5e-26 91.7 0.0 7.1e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Acetyltransf_8 PF13523.6 KFP06465.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Aa_trans PF01490.18 KFP06466.1 - 3.4e-75 253.3 40.8 4.2e-75 253.0 40.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein C2 PF00168.30 KFP06467.1 - 1e-14 54.6 0.0 1.3e-14 54.4 0.0 1.0 1 0 0 1 1 1 1 C2 domain Aida_C2 PF14186.6 KFP06467.1 - 0.052 13.2 0.2 0.37 10.4 0.2 1.8 1 1 1 2 2 2 0 Cytoskeletal adhesion DUF3869 PF12985.7 KFP06467.1 - 0.077 13.4 0.4 0.18 12.2 0.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3869) C1_1 PF00130.22 KFP06468.1 - 4.9e-33 112.8 30.5 4.9e-17 61.6 6.4 2.2 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KFP06468.1 - 2.1e-05 24.7 16.6 0.0059 16.9 2.6 2.5 2 0 0 2 2 2 2 C1 domain Zf_RING PF16744.5 KFP06468.1 - 0.05 13.7 16.7 0.37 10.9 6.4 2.4 2 0 0 2 2 2 0 KIAA1045 RING finger SpmSyn_N PF17950.1 KFP06468.1 - 0.076 13.2 0.1 0.19 11.9 0.0 1.7 1 1 0 1 1 1 0 S-adenosylmethionine decarboxylase N -terminal FYVE_2 PF02318.16 KFP06468.1 - 1.1 9.4 18.2 2.8 8.2 7.1 2.3 1 1 0 2 2 2 0 FYVE-type zinc finger HLH PF00010.26 KFP06469.1 - 6e-05 22.9 0.6 6.7e-05 22.8 0.6 1.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HIF-1 PF11413.8 KFP06470.1 - 4.7e-16 57.9 5.2 1.1e-15 56.7 5.2 1.7 1 0 0 1 1 1 1 Hypoxia-inducible factor-1 C2 PF00168.30 KFP06471.1 - 8.2e-18 64.6 0.1 1.7e-08 34.7 0.0 2.2 2 0 0 2 2 2 2 C2 domain UPF0730 PF15827.5 KFP06472.1 - 1.5e-27 95.0 7.3 2.8e-27 94.2 7.3 1.5 1 0 0 1 1 1 1 UPF0730 unknown protein family SERTA PF06031.13 KFP06472.1 - 2.9e-14 52.4 2.4 4.5e-14 51.8 2.4 1.3 1 0 0 1 1 1 1 SERTA motif Ion_trans PF00520.31 KFP06473.1 - 2.7e-36 125.0 10.2 3.7e-36 124.6 10.2 1.2 1 0 0 1 1 1 1 Ion transport protein PAS_9 PF13426.7 KFP06473.1 - 8.6e-17 61.3 0.0 2.6e-16 59.7 0.0 1.9 1 0 0 1 1 1 1 PAS domain Ion_trans_2 PF07885.16 KFP06473.1 - 5.1e-13 48.8 2.7 5.1e-13 48.8 2.7 2.0 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 KFP06473.1 - 5.6e-13 48.8 0.0 1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PAS PF00989.25 KFP06473.1 - 5.4e-07 29.6 0.0 1.5e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 KFP06473.1 - 0.00019 21.7 0.0 0.00038 20.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold Cupin_2 PF07883.11 KFP06473.1 - 0.013 15.2 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Cupin domain PAS_4 PF08448.10 KFP06473.1 - 0.015 15.5 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 PAS fold NPV_P10 PF05531.12 KFP06473.1 - 0.016 15.7 1.6 0.054 14.0 1.6 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Cupin_3 PF05899.12 KFP06473.1 - 0.054 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Ras PF00071.22 KFP06474.1 - 1.4e-48 164.6 0.0 1.6e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP06474.1 - 1.4e-18 67.3 0.0 2e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP06474.1 - 2.5e-05 23.8 0.0 3.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family TniB PF05621.11 KFP06474.1 - 0.09 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Cys_knot PF00007.22 KFP06475.1 - 1.8e-17 63.5 7.1 2.1e-17 63.3 7.1 1.1 1 0 0 1 1 1 1 Cystine-knot domain DAN PF03045.15 KFP06475.1 - 0.0055 16.7 2.8 0.0084 16.1 2.8 1.3 1 1 0 1 1 1 1 DAN domain B56 PF01603.20 KFP06476.1 - 2.2e-187 623.1 9.9 2.6e-187 622.9 9.9 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) SBF2 PF12335.8 KFP06476.1 - 0.094 12.3 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Myotubularin protein HAD_2 PF13419.6 KFP06476.1 - 0.12 12.5 0.2 0.97 9.5 0.1 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Sec7_N PF12783.7 KFP06476.1 - 0.12 12.3 6.5 0.88 9.5 0.6 3.0 3 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal WD40 PF00400.32 KFP06477.1 - 2.6e-12 47.0 11.1 0.022 15.6 0.0 6.5 6 1 1 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP06477.1 - 4.9e-07 30.0 0.1 0.5 10.7 0.0 5.0 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KFP06477.1 - 0.058 12.1 0.0 5.9 5.5 0.0 2.4 1 1 0 2 2 2 0 Nup133 N terminal like SARS_X4 PF08779.10 KFP06477.1 - 0.1 12.8 0.1 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 SARS coronavirus X4 like PAP2 PF01569.21 KFP06478.1 - 3.8e-16 59.1 5.3 9.7e-16 57.8 5.3 1.7 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KFP06478.1 - 5.1e-06 26.3 4.9 5.1e-06 26.3 4.9 1.9 1 1 0 1 1 1 1 PAP2 superfamily DUF202 PF02656.15 KFP06478.1 - 2.2 8.8 10.3 1.9 9.0 0.1 3.9 2 2 1 3 3 3 0 Domain of unknown function (DUF202) ERbeta_N PF12497.8 KFP06479.1 - 1e-52 176.7 7.7 1.8e-52 176.0 7.7 1.4 1 0 0 1 1 1 1 Estrogen receptor beta Hormone_recep PF00104.30 KFP06479.1 - 6.1e-34 117.4 1.4 9e-34 116.9 1.4 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFP06479.1 - 1.6e-31 108.5 13.3 3.2e-31 107.6 13.3 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) FTHFS PF01268.19 KFP06480.1 - 8.8e-261 865.9 0.0 1.2e-260 865.5 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KFP06480.1 - 2.6e-67 225.1 1.6 2.6e-67 225.1 1.6 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KFP06480.1 - 2.9e-31 108.1 0.2 6.4e-31 107.0 0.2 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain WSK PF03832.13 KFP06481.1 - 1.1 9.0 9.7 0.054 13.2 3.2 2.4 2 0 0 2 2 2 0 WSK motif BTB PF00651.31 KFP06482.1 - 1.8e-20 73.2 0.3 5.5e-20 71.7 0.2 1.8 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2 PF00096.26 KFP06482.1 - 6.5e-08 32.6 16.8 0.00013 22.2 0.9 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP06482.1 - 6.3e-07 29.7 16.1 0.00056 20.5 0.7 3.4 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFP06482.1 - 0.0016 18.7 5.1 0.7 10.3 2.1 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KFP06482.1 - 0.0048 16.9 11.8 0.45 10.6 3.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HE PF16278.5 KFP06482.1 - 0.0052 17.2 4.6 0.51 10.8 0.1 2.9 3 0 0 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 KFP06482.1 - 0.017 15.4 6.2 0.042 14.2 1.4 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFP06482.1 - 0.034 14.1 2.9 0.25 11.3 0.1 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-met PF12874.7 KFP06482.1 - 0.11 13.0 4.8 0.15 12.5 0.4 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FYVE PF01363.21 KFP06482.1 - 0.5 10.5 6.7 8 6.7 3.5 2.5 2 0 0 2 2 2 0 FYVE zinc finger zf-Di19 PF05605.12 KFP06482.1 - 2 8.8 6.9 2 8.8 0.4 2.9 3 0 0 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding BTB PF00651.31 KFP06483.1 - 3.4e-19 69.1 1.4 3.4e-19 69.1 1.4 1.9 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2_4 PF13894.6 KFP06483.1 - 3.7e-11 42.9 60.7 0.15 13.0 0.1 10.3 9 0 0 9 9 9 6 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP06483.1 - 3.3e-08 33.5 64.2 0.039 14.4 0.1 10.4 10 0 0 10 10 10 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP06483.1 - 0.00071 19.9 2.6 0.00071 19.9 2.6 8.6 9 1 0 9 9 8 3 Zinc-finger double domain zf_UBZ PF18439.1 KFP06483.1 - 0.007 15.9 39.7 0.094 12.3 0.1 8.8 8 1 1 9 9 9 3 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 KFP06483.1 - 0.027 14.8 0.2 0.027 14.8 0.2 8.4 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding CpXC PF14353.6 KFP06483.1 - 0.046 13.8 22.0 2.9 7.9 2.7 5.7 3 1 2 5 5 5 0 CpXC protein zf-met PF12874.7 KFP06483.1 - 0.047 14.1 0.4 0.047 14.1 0.4 9.4 9 1 0 9 9 9 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFP06483.1 - 0.26 11.6 43.9 0.078 13.3 3.1 7.8 3 2 5 8 8 8 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 KFP06483.1 - 0.32 11.3 26.8 1.1 9.6 0.3 5.0 4 1 1 5 5 5 0 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 KFP06483.1 - 1.1 10.0 35.5 1.7 9.3 11.8 6.2 2 1 2 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_9 PF16293.5 KFP06483.1 - 8.4 6.3 13.1 7.9 6.4 0.1 5.1 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) HSP70 PF00012.20 KFP06484.1 - 1.2e-263 875.8 11.2 1.3e-263 875.7 11.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFP06484.1 - 2.4e-17 62.7 0.7 9.3e-16 57.5 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KFP06484.1 - 0.0006 19.6 0.0 0.0017 18.1 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KFP06484.1 - 0.00074 19.9 3.0 1.5 9.3 0.0 3.6 3 1 0 3 3 3 2 Cell division protein FtsA CRIC_ras_sig PF10534.9 KFP06484.1 - 0.0032 17.6 0.1 0.01 16.0 0.1 1.9 1 1 0 1 1 1 1 Connector enhancer of kinase suppressor of ras Hydantoinase_A PF01968.18 KFP06484.1 - 0.021 14.1 0.8 0.06 12.6 0.2 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase SHS2_FTSA PF02491.20 KFP06484.1 - 0.089 13.2 1.7 8.8 6.8 0.4 2.8 2 0 0 2 2 2 0 SHS2 domain inserted in FTSA TFIIB PF00382.19 KFP06485.1 - 1.3e-32 111.7 0.0 5.9e-16 58.3 0.0 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KFP06485.1 - 4.1e-27 94.5 11.0 4.1e-27 94.5 11.0 3.0 3 0 0 3 3 3 1 Brf1-like TBP-binding domain Cyclin_N PF00134.23 KFP06485.1 - 7.8e-08 32.1 0.2 0.00047 19.9 0.0 2.6 2 0 0 2 2 2 2 Cyclin, N-terminal domain RB_B PF01857.20 KFP06485.1 - 0.0028 17.7 0.2 0.0083 16.2 0.2 1.8 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain TFIIB_C_1 PF18542.1 KFP06485.1 - 0.0052 16.8 0.0 0.02 14.9 0.0 2.0 1 0 0 1 1 1 1 Transcription factor IIB C-terminal module 1 SNAD2 PF18745.1 KFP06485.1 - 0.15 11.8 2.0 0.3 10.7 2.0 1.5 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 2 PHR PF08005.12 KFP06486.1 - 1.4e-44 152.4 1.3 2.6e-44 151.6 1.3 1.4 1 0 0 1 1 1 1 PHR domain BTB PF00651.31 KFP06486.1 - 1e-24 86.9 0.1 1.4e-23 83.2 0.0 2.3 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFP06486.1 - 9.2e-08 32.1 3.3 1.3e-07 31.6 1.3 2.3 2 1 0 2 2 2 1 BTB And C-terminal Kelch DUF4082 PF13313.6 KFP06486.1 - 0.0017 18.4 0.1 0.0035 17.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4082) NUDIX PF00293.28 KFP06488.1 - 0.004 17.2 0.0 0.028 14.5 0.0 1.9 1 1 0 1 1 1 1 NUDIX domain ESPR PF13018.6 KFP06488.1 - 0.069 13.0 0.3 0.13 12.1 0.3 1.5 1 0 0 1 1 1 0 Extended Signal Peptide of Type V secretion system EGF PF00008.27 KFP06489.1 - 1.5e-76 252.2 285.8 1.1e-08 35.2 7.2 18.7 20 0 0 20 20 20 14 EGF-like domain hEGF PF12661.7 KFP06489.1 - 6.4e-44 147.2 246.5 7.7e-06 26.4 7.5 20.5 22 0 0 22 22 22 14 Human growth factor-like EGF MNNL PF07657.13 KFP06489.1 - 6.5e-27 93.4 1.6 6.5e-27 93.4 1.6 6.7 8 2 0 8 8 8 1 N terminus of Notch ligand DSL PF01414.19 KFP06489.1 - 2.3e-24 85.4 5.9 2.3e-24 85.4 5.9 13.6 10 3 3 13 13 13 3 Delta serrate ligand EGF_2 PF07974.13 KFP06489.1 - 7.6e-19 67.8 320.7 0.00033 20.9 6.6 20.3 20 0 0 20 20 20 13 EGF-like domain EGF_CA PF07645.15 KFP06489.1 - 4.8e-06 26.7 21.5 5.2e-05 23.4 7.3 19.8 9 4 11 20 20 20 10 Calcium-binding EGF domain Saf_2TM PF18303.1 KFP06489.1 - 0.15 11.6 0.1 0.22 11.1 0.1 1.2 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain SERTA PF06031.13 KFP06490.1 - 5.5e-18 64.3 2.2 1.2e-17 63.2 2.2 1.6 1 0 0 1 1 1 1 SERTA motif DUF4279 PF14106.6 KFP06490.1 - 0.026 14.7 0.3 0.065 13.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) DUF4521 PF15021.6 KFP06490.1 - 0.22 11.4 8.4 0.074 13.0 4.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4521) GET2 PF08690.10 KFP06490.1 - 0.29 10.8 6.9 0.4 10.3 6.9 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Clathrin_bdg PF15045.6 KFP06491.1 - 4.5e-30 103.5 0.7 1.2e-29 102.1 0.7 1.8 1 0 0 1 1 1 1 Clathrin-binding box of Aftiphilin, vesicle trafficking PDZ PF00595.24 KFP06493.1 - 1e-05 25.8 0.0 2.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain NTPase_1 PF03266.15 KFP06495.1 - 5.3e-56 189.1 0.2 5.9e-56 189.0 0.2 1.0 1 0 0 1 1 1 1 NTPase AAA_14 PF13173.6 KFP06495.1 - 0.05 13.6 0.1 7 6.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFP06495.1 - 0.063 13.0 0.3 0.21 11.3 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KFP06495.1 - 0.11 13.0 0.1 0.33 11.4 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFP06495.1 - 0.14 12.4 0.1 0.56 10.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain Pecanex_C PF05041.15 KFP06496.1 - 2e-114 380.9 0.0 3.1e-114 380.3 0.0 1.3 1 0 0 1 1 1 1 Pecanex protein (C-terminus) Pkinase_Tyr PF07714.17 KFP06497.1 - 2.2e-31 109.1 0.0 4.3e-31 108.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP06497.1 - 6.3e-26 91.3 0.0 1.4e-25 90.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain DUF3552 PF12072.8 KFP06497.1 - 0.21 11.0 14.6 0.36 10.2 14.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF3450 PF11932.8 KFP06497.1 - 3.8 6.7 10.8 6.5 6.0 10.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CN_hydrolase PF00795.22 KFP06498.1 - 1.1e-39 136.3 0.0 1.3e-39 136.2 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Pkinase PF00069.25 KFP06499.1 - 9.7e-67 225.1 0.0 1.1e-66 224.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP06499.1 - 3.1e-33 115.1 0.0 3.9e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP06499.1 - 1.1e-07 31.5 0.0 2.3e-07 30.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFP06499.1 - 0.0048 16.9 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFP06499.1 - 0.016 14.1 0.2 0.022 13.7 0.2 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KFP06499.1 - 0.043 12.6 0.0 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase CagZ PF09053.10 KFP06499.1 - 0.18 11.4 0.1 0.4 10.3 0.1 1.6 2 0 0 2 2 2 0 CagZ I-set PF07679.16 KFP06500.1 - 3.2e-160 520.7 0.0 1.2e-15 57.4 0.0 13.3 13 0 0 13 13 13 12 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP06500.1 - 2.5e-152 495.8 19.6 7.9e-14 52.0 0.0 14.1 13 0 0 13 13 13 12 Immunoglobulin domain ig PF00047.25 KFP06500.1 - 1.1e-104 342.8 0.0 3.4e-10 40.0 0.0 13.7 13 0 0 13 13 13 11 Immunoglobulin domain Ig_2 PF13895.6 KFP06500.1 - 8e-87 285.7 10.6 8.5e-10 38.8 0.0 13.1 13 0 0 13 13 13 11 Immunoglobulin domain V-set PF07686.17 KFP06500.1 - 6.2e-50 167.9 18.8 0.00028 21.0 0.0 16.0 12 5 0 12 12 12 10 Immunoglobulin V-set domain LRR_8 PF13855.6 KFP06500.1 - 5.6e-29 99.7 12.2 7e-12 44.9 0.7 5.2 3 1 2 5 5 5 4 Leucine rich repeat Ig_6 PF18452.1 KFP06500.1 - 1.2e-23 82.4 0.0 0.052 13.1 0.0 11.2 11 0 0 11 11 11 5 Immunoglobulin domain Izumo-Ig PF16706.5 KFP06500.1 - 2.5e-19 69.1 0.6 0.71 10.0 0.0 11.2 11 0 0 11 11 11 2 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 KFP06500.1 - 1.2e-10 41.3 0.3 2.3 8.3 0.0 9.3 10 0 0 10 10 10 1 C17orf99 Ig domain Ig_5 PF16681.5 KFP06500.1 - 1.4e-10 41.5 0.0 14 6.1 0.0 11.2 12 1 0 12 12 12 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain LRR_4 PF12799.7 KFP06500.1 - 2.8e-10 40.3 3.7 0.0023 18.3 0.0 4.0 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) Receptor_2B4 PF11465.8 KFP06500.1 - 3e-07 30.6 1.2 18 5.6 0.0 8.0 9 0 0 9 9 8 0 Natural killer cell receptor 2B4 LRR_5 PF13306.6 KFP06500.1 - 6.9e-06 26.0 0.0 2.2e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) Ig_4 PF16680.5 KFP06500.1 - 9.3e-06 25.8 1.0 12 6.3 0.0 9.1 11 1 0 11 11 10 0 T-cell surface glycoprotein CD3 delta chain C2-set PF05790.15 KFP06500.1 - 0.00092 19.4 0.0 0.54 10.5 0.0 5.2 6 0 0 6 6 5 1 Immunoglobulin C2-set domain Herpes_gE PF02480.16 KFP06500.1 - 0.0071 15.1 0.9 6 5.5 0.0 4.9 5 0 0 5 5 5 1 Alphaherpesvirus glycoprotein E AMP-binding_C_2 PF14535.6 KFP06500.1 - 0.14 12.5 0.1 13 6.1 0.0 3.9 4 0 0 4 4 4 0 AMP-binding enzyme C-terminal domain LRRNT PF01462.18 KFP06500.1 - 6.9 6.4 13.3 0.04 13.6 3.9 2.3 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KFP06500.1 - 9.5 7.2 8.3 55 4.9 0.4 5.3 6 0 0 6 6 4 0 Leucine Rich Repeat Sulfatase PF00884.23 KFP06501.1 - 9.5e-86 288.0 0.0 1.3e-85 287.5 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KFP06501.1 - 8.8e-51 171.8 0.1 1.5e-50 171.1 0.1 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 KFP06501.1 - 2.8e-10 40.3 0.0 0.00016 21.4 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KFP06501.1 - 0.099 11.2 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sulfatase PF00884.23 KFP06502.1 - 2.8e-42 145.2 0.0 4.7e-42 144.5 0.0 1.3 1 1 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KFP06502.1 - 7.1e-05 23.5 0.3 0.00015 22.5 0.3 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 KFP06502.1 - 0.00064 19.4 0.0 0.00085 19.0 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase ERG4_ERG24 PF01222.17 KFP06503.1 - 2.1e-182 606.7 10.6 2.6e-182 606.4 10.6 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family LBR_tudor PF09465.10 KFP06503.1 - 8.2e-30 102.4 0.3 1.6e-29 101.4 0.3 1.5 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain DUF1295 PF06966.12 KFP06503.1 - 3.7e-06 26.7 0.5 8.9e-06 25.4 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KFP06503.1 - 0.00036 20.9 0.5 0.0019 18.6 0.1 2.5 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 KFP06503.1 - 0.0025 18.2 0.3 0.0025 18.2 0.3 2.6 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Corona_nucleoca PF00937.18 KFP06503.1 - 0.27 10.2 8.4 0.42 9.6 8.4 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein MAJIN PF15077.6 KFP06503.1 - 0.38 10.5 5.0 0.054 13.3 0.7 1.7 2 0 0 2 2 2 0 Membrane-anchored junction protein TMEM40 PF15817.5 KFP06503.1 - 3.4 7.4 5.0 2.4 8.0 2.5 2.0 2 0 0 2 2 2 0 Transmembrane protein 40 family FoP_duplication PF13865.6 KFP06503.1 - 4.6 7.9 8.4 10 6.8 8.4 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 WH1 PF00568.23 KFP06504.1 - 7.2e-40 135.4 0.2 1e-39 134.9 0.2 1.2 1 0 0 1 1 1 1 WH1 domain VASP_tetra PF08776.11 KFP06504.1 - 2.6e-17 62.1 5.0 6.4e-17 60.8 5.0 1.6 1 0 0 1 1 1 1 VASP tetramerisation domain SRP9-21 PF05486.12 KFP06505.1 - 1.2e-06 28.7 0.1 2.1e-06 28.0 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) RSN1_7TM PF02714.15 KFP06506.1 - 1.3e-58 198.5 25.9 1.3e-58 198.5 25.9 3.4 2 1 1 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KFP06506.1 - 4.7e-45 154.0 0.7 7.5e-45 153.3 0.7 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KFP06506.1 - 2.4e-21 76.1 1.9 2.4e-21 76.1 1.9 4.7 4 1 0 5 5 5 2 Late exocytosis, associated with Golgi transport RRM_1 PF00076.22 KFP06506.1 - 0.0001 22.0 0.0 0.23 11.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MpPF26 PF07666.11 KFP06506.1 - 0.0041 17.2 2.9 0.0041 17.2 2.9 4.8 5 0 0 5 5 5 1 M penetrans paralogue family 26 TGFb_propeptide PF00688.18 KFP06507.1 - 1.6e-19 70.6 0.3 4.6e-18 65.8 0.1 2.1 2 0 0 2 2 2 2 TGF-beta propeptide TGF_beta PF00019.20 KFP06507.1 - 6.8e-14 52.7 4.2 9.9e-13 49.0 4.2 2.5 1 1 0 1 1 1 1 Transforming growth factor beta like domain Sde2_N_Ubi PF13019.6 KFP06508.1 - 3.6e-22 78.9 4.7 4.7e-22 78.6 4.5 1.3 1 1 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Rrn6 PF10214.9 KFP06508.1 - 0.012 14.1 7.0 0.015 13.8 7.0 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Exonuc_VII_L PF02601.15 KFP06508.1 - 0.025 14.1 1.7 0.029 14.0 1.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SART-1 PF03343.13 KFP06508.1 - 0.037 12.6 7.5 0.012 14.2 4.6 1.5 2 0 0 2 2 2 0 SART-1 family Histone PF00125.24 KFP06509.1 - 1.2e-43 148.6 0.4 1.3e-43 148.5 0.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KFP06509.1 - 4.4e-05 23.5 0.0 5.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KFP06509.1 - 0.00012 22.4 0.0 0.00015 22.0 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KFP06509.1 - 0.028 14.7 0.0 0.038 14.3 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFP06509.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit GOLD_2 PF13897.6 KFP06510.1 - 1.8e-70 235.8 5.8 1.8e-70 235.8 5.8 3.2 3 1 0 3 3 3 1 Golgi-dynamics membrane-trafficking ACBP PF00887.19 KFP06510.1 - 8e-13 48.4 0.0 2.6e-12 46.8 0.0 2.0 1 0 0 1 1 1 1 Acyl CoA binding protein DUF913 PF06025.12 KFP06510.1 - 3.8 6.4 14.4 1.5 7.7 8.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Anophelin PF10731.9 KFP06510.1 - 5 7.1 6.3 18 5.3 0.3 2.7 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito DUF3527 PF12043.8 KFP06510.1 - 9.6 5.7 16.5 0.46 10.0 10.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) Homeodomain PF00046.29 KFP06511.1 - 1.4e-11 44.0 0.2 1.7e-11 43.8 0.2 1.1 1 0 0 1 1 1 1 Homeodomain DIRP PF06584.13 KFP06512.1 - 1.9e-47 159.8 0.3 5.2e-47 158.4 0.3 1.8 1 0 0 1 1 1 1 DIRP DUF2664 PF10867.8 KFP06512.1 - 0.016 15.6 0.3 0.054 14.0 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2664) FTA4 PF13093.6 KFP06512.1 - 0.04 13.8 3.5 0.14 12.0 3.6 2.1 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Med30 PF11315.8 KFP06512.1 - 0.37 11.0 3.9 0.22 11.7 0.9 2.1 2 1 0 2 2 2 0 Mediator complex subunit 30 zf-PARP PF00645.18 KFP06513.1 - 2.6e-13 50.6 8.0 3.2e-07 31.1 0.2 2.2 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Spec3 PF15795.5 KFP06514.1 - 2.8e-28 98.3 9.1 3.5e-28 98.0 9.1 1.1 1 0 0 1 1 1 1 Ectodermal ciliogenesis protein NrsF PF06532.11 KFP06514.1 - 0.0012 18.6 1.9 0.0016 18.2 1.9 1.2 1 0 0 1 1 1 1 Negative regulator of sigma F NDUF_B12 PF08122.12 KFP06514.1 - 0.066 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family Sec23_trunk PF04811.15 KFP06515.1 - 4.9e-78 262.0 0.0 7.1e-78 261.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KFP06515.1 - 2.5e-30 105.1 0.0 5.8e-30 103.9 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KFP06515.1 - 1.8e-26 91.9 0.1 5.3e-26 90.4 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 KFP06515.1 - 4.3e-16 58.6 0.0 1.5e-15 56.8 0.0 2.0 2 0 0 2 2 2 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 KFP06515.1 - 3.5e-15 55.8 5.9 6.4e-15 54.9 5.9 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Tyr_Deacylase PF02580.16 KFP06516.1 - 2.3e-44 151.4 0.0 2.9e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Laminin_G_2 PF02210.24 KFP06518.1 - 5.2e-135 443.9 9.4 1.4e-28 100.0 0.0 5.2 5 0 0 5 5 5 5 Laminin G domain Laminin_G_1 PF00054.23 KFP06518.1 - 1.4e-87 290.6 4.4 1e-24 87.2 0.0 6.5 5 1 0 5 5 5 5 Laminin G domain Laminin_G_3 PF13385.6 KFP06518.1 - 3.9e-17 62.8 3.3 0.011 15.9 0.1 5.4 5 0 0 5 5 5 5 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 KFP06518.1 - 8.3e-09 35.6 17.5 1.2e-05 25.5 6.7 2.7 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 KFP06518.1 - 9.1e-05 23.0 14.7 0.02 15.5 5.3 3.0 2 0 0 2 2 2 2 Human growth factor-like EGF DUF1080 PF06439.11 KFP06518.1 - 0.00065 19.9 0.0 7.3 6.7 0.0 3.6 3 0 0 3 3 3 2 Domain of Unknown Function (DUF1080) Yae1_N PF09811.9 KFP06519.1 - 3e-07 30.0 17.9 0.00039 20.1 7.0 2.5 2 1 0 2 2 2 2 Essential protein Yae1, N terminal Lipase_GDSL_2 PF13472.6 KFP06520.1 - 0.0011 19.4 0.0 0.0031 18.0 0.0 1.8 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 KFP06520.1 - 0.0049 16.1 0.0 0.0089 15.3 0.0 1.3 1 0 0 1 1 1 1 OSK domain Tmemb_cc2 PF10267.9 KFP06520.1 - 0.072 12.2 0.4 0.11 11.7 0.4 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein RasGEF_N_2 PF14663.6 KFP06520.1 - 0.17 12.3 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Lipase_GDSL PF00657.22 KFP06520.1 - 0.23 11.4 0.0 0.85 9.6 0.0 1.9 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase 7tm_1 PF00001.21 KFP06521.1 - 1.3e-34 119.8 27.8 2.3e-34 118.9 27.8 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GnHR_trans PF12369.8 KFP06521.1 - 2.2e-13 50.8 0.1 4.9e-13 49.7 0.1 1.6 1 0 0 1 1 1 1 Gonadotropin hormone receptor transmembrane region LRR_8 PF13855.6 KFP06521.1 - 2e-11 43.5 9.9 2.6e-05 23.9 1.4 4.0 3 1 1 4 4 4 4 Leucine rich repeat LRR_5 PF13306.6 KFP06521.1 - 7.7e-06 25.9 0.1 3.3e-05 23.8 0.1 1.8 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFP06521.1 - 0.079 13.4 14.1 0.56 10.7 2.5 3.9 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) 7tm_1 PF00001.21 KFP06522.1 - 2.8e-35 121.9 19.4 4e-35 121.4 19.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.6 KFP06522.1 - 1.6e-14 53.4 5.6 0.0001 22.0 0.1 4.7 1 1 5 6 6 6 6 Leucine rich repeat LRR_5 PF13306.6 KFP06522.1 - 1.8e-11 44.1 0.2 0.00014 21.9 0.0 2.5 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) GnHR_trans PF12369.8 KFP06522.1 - 0.0075 17.1 0.7 0.016 16.0 0.7 1.5 1 0 0 1 1 1 1 Gonadotropin hormone receptor transmembrane region LRR_9 PF14580.6 KFP06522.1 - 0.048 13.2 0.2 0.11 12.0 0.2 1.5 1 0 0 1 1 1 0 Leucine-rich repeat LRR_4 PF12799.7 KFP06522.1 - 2.2 8.8 9.5 0.64 10.5 0.2 3.4 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) TFIIA PF03153.13 KFP06523.1 - 4e-111 373.0 18.1 1e-110 371.7 18.1 1.7 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Adap_comp_sub PF00928.21 KFP06523.1 - 2.5e-57 194.2 0.4 4.3e-57 193.5 0.4 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Beta_helix PF13229.6 KFP06524.1 - 1.2e-64 216.9 60.9 2.4e-26 92.5 14.7 4.5 1 1 3 4 4 4 4 Right handed beta helix region NosD PF05048.13 KFP06524.1 - 8.1e-38 130.0 30.3 2.9e-15 56.2 7.5 4.2 1 1 2 3 3 3 3 Periplasmic copper-binding protein (NosD) F-box-like PF12937.7 KFP06524.1 - 6.6e-16 57.9 0.3 1.3e-15 57.0 0.3 1.5 1 0 0 1 1 1 1 F-box-like zf-UBR PF02207.20 KFP06524.1 - 4.6e-09 36.3 13.1 4.6e-09 36.3 13.1 2.1 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) F-box PF00646.33 KFP06524.1 - 5e-08 32.6 0.3 5e-08 32.6 0.3 1.9 2 0 0 2 2 2 1 F-box domain I-set PF07679.16 KFP06525.1 - 1.1e-70 233.8 0.0 1.5e-16 60.2 0.0 6.5 6 0 0 6 6 6 5 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP06525.1 - 2.5e-64 213.8 7.4 1.9e-12 47.6 0.0 6.7 8 0 0 8 8 8 5 Immunoglobulin domain ig PF00047.25 KFP06525.1 - 1.5e-45 153.3 0.6 8.2e-09 35.5 0.0 7.0 6 1 0 6 6 6 5 Immunoglobulin domain fn3 PF00041.21 KFP06525.1 - 5.6e-45 151.6 19.5 1.3e-14 54.3 1.7 4.4 4 0 0 4 4 4 4 Fibronectin type III domain Ig_2 PF13895.6 KFP06525.1 - 1.8e-43 146.7 0.1 1.2e-09 38.4 0.0 5.5 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.17 KFP06525.1 - 3.9e-28 97.8 10.6 0.0016 18.5 0.1 10.3 7 4 1 8 8 8 6 Immunoglobulin V-set domain Ig_5 PF16681.5 KFP06525.1 - 9.9e-11 41.9 0.0 0.087 13.2 0.0 5.9 6 0 0 6 6 5 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFP06525.1 - 1.9e-10 40.2 0.0 0.63 9.6 0.0 5.4 5 0 0 5 5 5 4 Immunoglobulin domain Tissue_fac PF01108.17 KFP06525.1 - 4.5e-07 29.7 4.9 3e-05 23.8 0.5 3.5 2 1 1 3 3 3 1 Tissue factor Izumo-Ig PF16706.5 KFP06525.1 - 3.3e-06 27.1 0.1 6.2 7.0 0.0 5.4 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 KFP06525.1 - 0.0014 18.7 5.1 2 8.5 0.0 5.0 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFP06525.1 - 0.0049 17.4 10.4 0.14 12.7 0.5 3.7 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFP06525.1 - 0.0053 17.1 0.1 5.9 7.3 0.0 3.4 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III Ig_C17orf99 PF17736.1 KFP06525.1 - 0.0087 16.1 0.0 12 6.0 0.0 4.5 6 0 0 6 6 4 0 C17orf99 Ig domain Egh16-like PF11327.8 KFP06525.1 - 0.009 16.4 0.1 0.054 13.9 0.0 2.4 2 0 0 2 2 2 1 Egh16-like virulence factor V-set_CD47 PF08204.11 KFP06525.1 - 0.0097 15.9 0.4 39 4.2 0.0 4.1 4 0 0 4 4 4 0 CD47 immunoglobulin-like domain Big_4 PF07532.11 KFP06525.1 - 0.12 12.2 5.8 4.7 7.0 0.1 4.1 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 4) Ig_3 PF13927.6 KFP06526.1 - 2.4e-72 239.6 1.3 1.5e-12 48.0 0.0 7.1 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 KFP06526.1 - 3.7e-70 232.0 0.1 7.6e-13 48.3 0.0 7.0 8 0 0 8 8 7 6 Immunoglobulin I-set domain fn3 PF00041.21 KFP06526.1 - 6.8e-53 177.0 5.5 4.1e-12 46.3 0.0 5.6 5 0 0 5 5 5 5 Fibronectin type III domain Ig_2 PF13895.6 KFP06526.1 - 5.5e-49 164.4 0.5 6.8e-09 36.0 0.0 6.8 7 0 0 7 7 6 6 Immunoglobulin domain ig PF00047.25 KFP06526.1 - 3.4e-44 148.9 2.3 1.4e-08 34.8 0.0 7.1 7 1 0 7 7 7 6 Immunoglobulin domain Bravo_FIGEY PF13882.6 KFP06526.1 - 1.1e-29 103.6 3.9 2.3e-29 102.6 3.9 1.6 1 0 0 1 1 1 1 Bravo-like intracellular region V-set PF07686.17 KFP06526.1 - 2.3e-23 82.4 5.0 0.00087 19.4 0.0 9.5 6 4 2 8 8 8 4 Immunoglobulin V-set domain Ig_4 PF16680.5 KFP06526.1 - 6.1e-10 39.2 0.0 1.3 9.4 0.0 5.8 6 0 0 6 6 6 3 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFP06526.1 - 1.1e-08 35.1 0.1 0.17 12.0 0.0 5.7 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFP06526.1 - 4e-08 32.7 0.0 0.0059 16.1 0.0 4.3 5 0 0 5 5 5 2 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFP06526.1 - 0.0014 19.2 1.9 53 4.5 0.0 4.9 3 2 0 4 4 4 0 Purple acid Phosphatase, N-terminal domain Izumo-Ig PF16706.5 KFP06526.1 - 0.0015 18.5 0.0 14 5.9 0.0 4.8 5 0 0 5 5 5 0 Izumo-like Immunoglobulin domain C2-set PF05790.15 KFP06526.1 - 0.005 17.0 0.5 18 5.6 0.0 4.5 6 0 0 6 6 4 0 Immunoglobulin C2-set domain Receptor_2B4 PF11465.8 KFP06526.1 - 0.0075 16.5 0.2 17 5.6 0.0 3.7 3 1 1 4 4 4 0 Natural killer cell receptor 2B4 fn3_2 PF16893.5 KFP06526.1 - 0.032 14.4 0.0 0.26 11.5 0.0 2.5 3 0 0 3 3 2 0 Fibronectin type III domain HBS1_N PF08938.10 KFP06527.1 - 0.067 13.5 0.0 2 8.7 0.0 2.5 2 0 0 2 2 2 0 HBS1 N-terminus MerR-DNA-bind PF09278.11 KFP06527.1 - 0.14 12.7 0.1 0.32 11.6 0.1 1.7 1 0 0 1 1 1 0 MerR, DNA binding DUF2312 PF10073.9 KFP06527.1 - 0.52 10.0 2.8 0.54 9.9 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Lipase_GDSL_2 PF13472.6 KFP06528.1 - 0.00017 22.0 0.0 0.00037 20.9 0.0 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family NAPRTase_N PF17767.1 KFP06528.1 - 0.05 14.0 0.0 0.084 13.3 0.0 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DUF16 PF01519.16 KFP06528.1 - 0.061 13.8 0.2 0.12 12.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF1192 PF06698.11 KFP06528.1 - 0.32 11.1 1.5 0.8 9.8 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) BTB PF00651.31 KFP06529.1 - 7.7e-33 113.0 1.1 2.6e-32 111.3 0.4 2.0 2 0 0 2 2 2 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFP06529.1 - 3.7e-06 27.1 1.0 3.7e-06 27.1 1.0 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP06529.1 - 0.0018 19.0 0.9 0.37 11.7 0.1 3.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 KFP06529.1 - 0.0026 18.1 0.9 0.5 10.8 0.2 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type BSP_II PF05432.11 KFP06529.1 - 0.0056 16.4 10.4 0.0088 15.8 10.4 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) zf-Di19 PF05605.12 KFP06529.1 - 0.0062 16.8 0.3 0.014 15.7 0.3 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KFP06529.1 - 0.0091 16.4 1.5 0.96 10.0 0.1 3.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type BUD22 PF09073.10 KFP06529.1 - 0.059 12.7 5.0 0.083 12.2 5.0 1.2 1 0 0 1 1 1 0 BUD22 DUF4611 PF15387.6 KFP06529.1 - 0.36 11.1 9.6 0.75 10.0 9.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF719 PF05334.13 KFP06529.1 - 0.45 10.7 1.9 0.76 10.0 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF719) TFB6 PF17110.5 KFP06529.1 - 0.62 9.8 4.1 1.1 8.9 4.1 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH SDA1 PF05285.12 KFP06529.1 - 0.88 8.9 13.4 1.4 8.3 13.4 1.2 1 0 0 1 1 1 0 SDA1 FAM176 PF14851.6 KFP06529.1 - 1.2 8.8 9.9 2.3 7.9 9.9 1.4 1 0 0 1 1 1 0 FAM176 family Radial_spoke PF04712.12 KFP06529.1 - 1.3 7.9 11.7 2.2 7.1 11.7 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein CobT PF06213.12 KFP06529.1 - 1.4 8.2 12.2 2.2 7.6 12.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PI3K_1B_p101 PF10486.9 KFP06529.1 - 2.2 6.0 6.5 3 5.5 6.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TRAP_alpha PF03896.16 KFP06529.1 - 2.2 7.4 7.4 3.5 6.7 7.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2722 PF10846.8 KFP06529.1 - 2.2 7.1 7.2 3.1 6.6 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2457 PF10446.9 KFP06529.1 - 2.2 7.3 18.3 3.3 6.8 18.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 KFP06529.1 - 3.5 5.8 11.0 4.9 5.3 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.8 KFP06529.1 - 3.8 7.7 16.8 9.2 6.5 16.8 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RRN3 PF05327.11 KFP06529.1 - 4.5 5.7 12.4 6.3 5.2 12.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 KFP06529.1 - 5.8 4.9 19.8 8.3 4.4 19.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KFP06529.1 - 7.9 4.6 18.3 11 4.0 18.3 1.1 1 0 0 1 1 1 0 Nop14-like family PTPRCAP PF15713.5 KFP06529.1 - 8.4 6.7 16.3 16 5.7 16.3 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated MH2 PF03166.14 KFP06530.1 - 1.2e-79 266.9 0.1 1.7e-79 266.4 0.1 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 KFP06530.1 - 2.9e-45 152.7 4.5 5.3e-45 151.8 4.5 1.5 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.9 KFP06530.1 - 0.0062 16.4 0.0 0.0096 15.7 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 PI3_PI4_kinase PF00454.27 KFP06531.1 - 5.9e-50 170.4 1.3 4.4e-48 164.3 1.3 2.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KFP06531.1 - 1.6e-30 105.9 4.6 1.6e-30 105.9 4.6 2.6 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PX PF00787.24 KFP06531.1 - 4e-11 42.9 1.1 1.6e-10 41.0 1.1 2.0 1 0 0 1 1 1 1 PX domain C2 PF00168.30 KFP06531.1 - 6.6e-07 29.6 0.0 4e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 C2 domain PI3K_C2 PF00792.24 KFP06531.1 - 0.00021 21.2 0.2 0.00076 19.4 0.2 1.9 1 1 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 KFP06531.1 - 0.00084 18.8 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) PI3K_rbd PF00794.18 KFP06531.1 - 0.029 14.5 0.3 0.12 12.5 0.0 2.2 3 0 0 3 3 3 0 PI3-kinase family, ras-binding domain PI-PLC-X PF00388.19 KFP06532.1 - 1.1e-63 213.2 0.1 1.9e-63 212.4 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFP06532.1 - 1.3e-42 144.7 0.1 3e-42 143.6 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 KFP06532.1 - 3.6e-22 78.7 0.2 8.8e-22 77.4 0.2 1.7 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 KFP06532.1 - 2.5e-16 59.8 0.0 7.7e-16 58.3 0.0 1.9 1 0 0 1 1 1 1 C2 domain 7tm_4 PF13853.6 KFP06533.1 - 8.7e-08 32.2 0.8 1e-07 32.0 0.8 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP06533.1 - 6.9e-06 25.6 0.1 9.9e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CholecysA-Rec_N PF09193.10 KFP06533.1 - 0.022 14.7 0.1 0.041 13.9 0.1 1.5 1 1 0 1 1 1 0 Cholecystokinin A receptor, N-terminal RVT_1 PF00078.27 KFP06534.1 - 5.5e-23 81.6 0.0 6.5e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Thiolase_N PF00108.23 KFP06535.1 - 5.9e-75 252.0 0.0 6.6e-75 251.8 0.0 1.0 1 0 0 1 1 1 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.26 KFP06535.1 - 0.015 14.9 0.4 0.031 13.9 0.4 1.6 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain zf-CSL PF05207.13 KFP06536.1 - 2.2e-15 56.1 0.3 3.4e-15 55.5 0.3 1.3 1 0 0 1 1 1 1 CSL zinc finger zf-RING_7 PF02591.15 KFP06536.1 - 0.0093 16.1 0.3 0.033 14.4 0.1 2.0 2 0 0 2 2 2 1 C4-type zinc ribbon domain NAD_binding_1 PF00175.21 KFP06537.1 - 1.9e-13 51.0 0.0 6e-13 49.4 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KFP06537.1 - 6.4e-08 32.9 0.0 1.2e-06 28.8 0.0 2.2 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Raftlin PF15250.6 KFP06538.1 - 9e-219 727.0 0.2 1.4e-218 726.4 0.2 1.3 1 0 0 1 1 1 1 Raftlin PilO PF04350.13 KFP06538.1 - 0.08 13.1 0.7 0.2 11.8 0.0 1.9 2 0 0 2 2 2 0 Pilus assembly protein, PilO RRM_1 PF00076.22 KFP06539.1 - 4.6e-14 52.0 0.5 6.9e-14 51.4 0.5 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP06539.1 - 0.0033 17.5 0.3 0.014 15.5 0.3 2.0 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 KFP06539.1 - 0.0046 16.5 0.0 0.0075 15.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PI-PLC-X PF00388.19 KFP06540.1 - 3.6e-61 205.0 0.1 7.7e-61 203.9 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFP06540.1 - 6.5e-39 132.8 0.2 1.7e-38 131.5 0.2 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain PH_12 PF16457.5 KFP06540.1 - 1.1e-21 77.8 0.2 5.5e-21 75.5 0.1 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain EF-hand_like PF09279.11 KFP06540.1 - 1.1e-16 61.1 0.0 2.3e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 KFP06540.1 - 1.3e-16 60.8 0.0 3e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain PH_14 PF17787.1 KFP06540.1 - 1e-06 28.6 0.3 4.1e-06 26.7 0.1 2.1 2 0 0 2 2 2 1 PH domain PH PF00169.29 KFP06540.1 - 2e-05 25.0 0.1 6.5e-05 23.4 0.1 2.0 1 0 0 1 1 1 1 PH domain Mcp5_PH PF12814.7 KFP06540.1 - 0.00055 20.0 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Pinin_SDK_N PF04697.13 KFP06540.1 - 0.48 11.1 2.4 1.4 9.6 2.4 1.8 1 0 0 1 1 1 0 pinin/SDK conserved region RabGAP-TBC PF00566.18 KFP06541.1 - 1.1e-26 93.8 12.2 4.5e-25 88.6 12.2 3.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Protamine_P2 PF00841.19 KFP06541.1 - 0.32 11.5 3.6 1.1 9.8 3.6 1.9 1 0 0 1 1 1 0 Sperm histone P2 RVT_1 PF00078.27 KFP06542.1 - 0.1 12.1 0.0 7.3 6.0 0.0 2.6 3 0 0 3 3 3 0 Reverse transcriptase (RNA-dependent DNA polymerase) CUTL PF16557.5 KFP06543.1 - 4.4e-43 145.3 0.9 2.1e-42 143.1 0.5 2.4 2 0 0 2 2 2 1 CUT1-like DNA-binding domain of SATB ULD PF16534.5 KFP06543.1 - 3.9e-37 126.6 0.0 1.4e-36 124.9 0.0 2.1 1 0 0 1 1 1 1 Ubiquitin-like oligomerisation domain of SATB CUT PF02376.15 KFP06543.1 - 8.4e-31 106.0 2.7 1.4e-23 82.9 0.1 3.1 3 0 0 3 3 3 2 CUT domain Homeodomain PF00046.29 KFP06543.1 - 5.5e-07 29.3 0.0 1.4e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Homeodomain SUIM_assoc PF16619.5 KFP06543.1 - 0.0042 17.1 6.0 0.0042 17.1 6.0 2.6 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 HTH_3 PF01381.22 KFP06543.1 - 0.06 13.4 0.0 0.55 10.3 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix RuvA_C PF07499.13 KFP06543.1 - 0.15 12.6 0.1 0.8 10.2 0.1 2.2 2 0 0 2 2 2 0 RuvA, C-terminal domain RAB3GAP2_N PF14655.6 KFP06543.1 - 1.2 8.3 4.2 5.1 6.2 3.5 2.0 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Herpes_TAF50 PF03326.13 KFP06543.1 - 2.9 6.4 24.9 0.017 13.8 8.5 2.2 2 0 0 2 2 2 0 Herpesvirus transcription activation factor (transactivator) HSA PF07529.13 KFP06544.1 - 9e-23 80.4 14.0 9e-23 80.4 14.0 2.2 1 1 1 2 2 2 1 HSA DUF2009 PF09418.10 KFP06544.1 - 0.027 13.5 8.6 0.029 13.4 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) DBINO PF13892.6 KFP06544.1 - 0.065 13.6 29.7 0.32 11.4 29.8 1.8 1 1 0 1 1 1 0 DNA-binding domain NAT PF04768.13 KFP06544.1 - 0.56 9.8 5.8 0.35 10.5 1.5 2.0 1 1 1 2 2 2 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase Goodbye PF17109.5 KFP06544.1 - 0.58 10.6 8.6 1.4 9.3 1.1 2.1 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain CorA PF01544.18 KFP06544.1 - 0.71 9.1 10.8 0.86 8.9 10.8 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein RNase_PH PF01138.21 KFP06545.1 - 2.4e-16 60.4 0.1 1.1e-15 58.3 0.0 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFP06545.1 - 2.4e-07 30.7 0.0 3.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Pneumo_matrix PF03393.16 KFP06545.1 - 0.16 11.2 0.1 0.21 10.8 0.1 1.1 1 0 0 1 1 1 0 Pneumovirus matrix protein zf-C3HC4_2 PF13923.6 KFP06546.1 - 4.7e-16 58.3 10.4 7.3e-16 57.7 10.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP06546.1 - 7.9e-11 41.6 10.3 1.2e-10 41.0 10.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP06546.1 - 4.7e-09 36.4 8.7 7.6e-09 35.8 8.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFP06546.1 - 4.4e-08 32.9 7.9 6.4e-08 32.3 7.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP06546.1 - 2.4e-06 27.5 7.3 4.7e-06 26.5 7.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP06546.1 - 2.7e-05 24.0 8.6 4.5e-05 23.3 8.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFP06546.1 - 4.4e-05 23.5 7.9 8e-05 22.7 7.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KFP06546.1 - 4.9e-05 23.1 5.3 8.3e-05 22.3 5.3 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 KFP06546.1 - 0.00014 21.6 3.9 0.00024 20.9 3.9 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KFP06546.1 - 0.00022 20.9 7.1 0.00047 19.9 7.1 1.5 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KFP06546.1 - 0.00086 19.5 7.4 0.0024 18.1 7.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFP06546.1 - 0.019 14.8 9.0 0.3 11.0 9.4 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_5 PF17121.5 KFP06546.1 - 0.039 13.8 8.1 0.16 11.9 8.0 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Trypan_PARP PF05887.11 KFP06546.1 - 0.089 12.8 2.2 0.13 12.3 2.2 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) zf-RING_11 PF17123.5 KFP06546.1 - 0.18 11.6 4.8 0.44 10.3 4.8 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-UDP PF14569.6 KFP06546.1 - 0.19 11.9 4.8 0.43 10.7 4.8 1.5 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-C4_Topoisom PF01396.19 KFP06546.1 - 0.43 10.4 3.6 0.19 11.6 0.9 1.8 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-MIZ PF02891.20 KFP06546.1 - 0.57 10.0 6.9 1.1 9.1 6.9 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DZR PF12773.7 KFP06546.1 - 1.5 8.9 6.8 23 5.1 6.8 2.4 1 1 0 1 1 1 0 Double zinc ribbon TetR_C_13 PF16925.5 KFP06547.1 - 0.073 13.0 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain zf-C4H2 PF10146.9 KFP06548.1 - 7.3e-79 265.0 21.2 8.4e-79 264.8 21.2 1.0 1 0 0 1 1 1 1 Zinc finger-containing protein DZR PF12773.7 KFP06548.1 - 0.0079 16.2 1.1 0.016 15.2 1.1 1.5 1 0 0 1 1 1 1 Double zinc ribbon Sec20 PF03908.13 KFP06548.1 - 0.0099 15.8 4.3 0.015 15.2 0.2 2.3 1 1 1 2 2 2 1 Sec20 DUF16 PF01519.16 KFP06548.1 - 0.049 14.1 1.5 0.049 14.1 1.5 2.5 1 1 2 3 3 3 0 Protein of unknown function DUF16 CENP-O PF09496.10 KFP06548.1 - 0.059 13.3 4.5 0.11 12.5 4.1 1.7 1 1 0 1 1 1 0 Cenp-O kinetochore centromere component zf-C3HC4_3 PF13920.6 KFP06548.1 - 0.065 13.1 4.2 0.12 12.3 4.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) BLOC1_2 PF10046.9 KFP06548.1 - 0.081 13.2 8.6 5.2 7.4 0.9 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-P11 PF03854.14 KFP06548.1 - 0.087 12.5 2.2 0.17 11.5 2.2 1.4 1 0 0 1 1 1 0 P-11 zinc finger Spc7 PF08317.11 KFP06548.1 - 0.11 11.3 15.6 0.062 12.2 13.9 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein zf-RING_4 PF14570.6 KFP06548.1 - 0.12 12.2 2.7 0.24 11.2 2.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Cytochrom_C_2 PF01322.20 KFP06548.1 - 0.19 12.6 0.4 0.19 12.6 0.4 2.3 2 1 0 2 2 2 0 Cytochrome C' Sec34 PF04136.15 KFP06548.1 - 0.28 11.1 8.1 0.23 11.3 2.2 2.2 1 1 1 2 2 2 0 Sec34-like family DUF1664 PF07889.12 KFP06548.1 - 0.51 10.4 4.9 1.8 8.6 4.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 KFP06548.1 - 1 9.7 17.2 2.4 8.6 17.2 1.6 1 1 0 1 1 1 0 Fez1 DUF3365 PF11845.8 KFP06548.1 - 2.4 8.5 7.1 3.3 8.0 7.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3365) YabA PF06156.13 KFP06548.1 - 3 8.5 16.0 1.2 9.8 3.9 2.5 1 1 1 2 2 2 0 Initiation control protein YabA V_ATPase_I PF01496.19 KFP06548.1 - 3.3 5.5 7.2 4 5.2 7.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FapA PF03961.13 KFP06548.1 - 3.6 6.1 8.6 5.4 5.5 8.6 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A DASH_Dad1 PF08649.10 KFP06548.1 - 5.3 7.3 6.5 1.3 9.2 0.5 2.7 3 0 0 3 3 3 0 DASH complex subunit Dad1 WAC_Acf1_DNA_bd PF10537.9 KFP06548.1 - 6.1 7.4 8.0 2.7 8.6 1.4 2.3 1 1 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal DUF3450 PF11932.8 KFP06548.1 - 7.8 5.7 18.8 0.42 9.9 5.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.8 KFP06548.1 - 7.9 6.7 18.6 6.9 6.9 9.4 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding FUSC PF04632.12 KFP06548.1 - 9.2 4.7 10.1 16 3.8 9.8 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family LMBR1 PF04791.16 KFP06548.1 - 9.7 5.0 5.8 11 4.8 5.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein RNase_Zc3h12a PF11977.8 KFP06549.1 - 4.7e-66 221.4 0.0 6.2e-66 221.0 0.0 1.2 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain UBA_6 PF18039.1 KFP06549.1 - 3.6e-19 68.4 0.2 9e-19 67.1 0.2 1.7 1 0 0 1 1 1 1 UBA-like domain zf-CCCH_4 PF18044.1 KFP06549.1 - 7.5e-05 22.4 7.0 0.00018 21.3 7.0 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger PRORP PF16953.5 KFP06549.1 - 0.14 11.6 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein-only RNase P Omega-toxin PF06357.11 KFP06549.1 - 0.88 9.4 7.8 0.083 12.7 3.0 1.7 2 0 0 2 2 2 0 Omega-atracotoxin zf-CCCH_2 PF14608.6 KFP06549.1 - 1.1 9.9 9.6 2.6 8.6 9.6 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 KFP06549.1 - 1.1 9.3 8.3 9.3 6.3 8.3 2.2 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Las1 PF04031.13 KFP06551.1 - 9.6e-43 145.9 0.0 1.3e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 Las1-like DnaB_C PF03796.15 KFP06551.1 - 0.21 10.9 0.0 0.25 10.6 0.0 1.1 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain ERM PF00769.19 KFP06552.1 - 1.1e-72 244.8 73.3 1.1e-72 244.8 73.3 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_C PF09380.10 KFP06552.1 - 9.1e-28 96.5 0.0 3.6e-27 94.6 0.0 2.1 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 KFP06552.1 - 2.2e-27 95.8 0.4 2.2e-27 95.8 0.4 3.8 2 1 1 3 3 3 1 FERM central domain FERM_N PF09379.10 KFP06552.1 - 4e-15 55.5 0.4 6.3e-14 51.7 0.1 2.6 2 0 0 2 2 2 1 FERM N-terminal domain Fer2 PF00111.27 KFP06553.1 - 4.7e-08 32.9 0.7 6.6e-08 32.4 0.7 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Zf_RING PF16744.5 KFP06553.1 - 0.05 13.7 0.2 0.45 10.7 0.3 2.0 1 1 1 2 2 2 0 KIAA1045 RING finger DUF3856 PF12968.7 KFP06553.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) RhoGAP PF00620.27 KFP06554.1 - 1.9e-35 121.9 0.1 1.3e-34 119.2 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain RA PF00788.23 KFP06554.1 - 3.9e-06 27.4 0.0 9.1e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PH PF00169.29 KFP06554.1 - 9.3e-06 26.1 0.1 2.7e-05 24.6 0.1 1.8 1 0 0 1 1 1 1 PH domain Ras_bdg_2 PF14847.6 KFP06554.1 - 0.0029 17.9 0.0 0.016 15.5 0.0 2.2 2 0 0 2 2 2 1 Ras-binding domain of Byr2 V-set PF07686.17 KFP06555.1 - 2.8e-18 66.1 0.1 1.6e-11 44.4 0.0 3.0 2 1 1 3 3 3 2 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP06555.1 - 2.6e-15 56.8 0.0 8.7e-10 39.1 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP06555.1 - 1.1e-13 51.3 0.0 4.7e-08 33.2 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP06555.1 - 1.4e-11 44.4 0.0 6.5e-05 23.0 0.0 2.7 2 2 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP06555.1 - 4.6e-09 36.2 0.0 0.0024 17.9 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_6 PF18452.1 KFP06555.1 - 0.0035 16.9 0.0 0.66 9.6 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFP06555.1 - 0.0055 16.7 0.0 16 5.6 0.0 3.2 3 0 0 3 3 3 1 C17orf99 Ig domain V-set_CD47 PF08204.11 KFP06555.1 - 0.041 13.9 0.0 0.086 12.8 0.0 1.5 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain Izumo-Ig PF16706.5 KFP06555.1 - 0.061 13.4 0.0 5.9 7.0 0.0 2.5 2 1 0 2 2 2 0 Izumo-like Immunoglobulin domain V-set PF07686.17 KFP06556.1 - 2.7e-14 53.2 0.0 3.8e-09 36.7 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP06556.1 - 1.4e-10 41.6 0.1 0.0014 19.2 0.0 3.3 2 2 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP06556.1 - 6.7e-09 35.7 0.0 0.00022 21.2 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP06556.1 - 3.9e-08 33.5 0.0 0.00075 19.8 0.0 2.8 3 1 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFP06556.1 - 5.8e-08 32.8 0.0 0.0071 16.5 0.0 2.6 3 0 0 3 3 3 2 Immunoglobulin domain Ig_6 PF18452.1 KFP06556.1 - 0.0005 19.6 0.0 0.098 12.2 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFP06556.1 - 0.018 15.1 0.0 6.7 6.8 0.0 2.4 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain HSF_DNA-bind PF00447.17 KFP06557.1 - 1.2e-24 86.8 1.1 2.5e-24 85.7 1.1 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Vert_HS_TF PF06546.11 KFP06557.1 - 2.8e-17 63.3 8.0 1.3e-16 61.1 8.0 2.0 1 1 0 1 1 1 1 Vertebrate heat shock transcription factor DUF2115 PF09888.9 KFP06557.1 - 0.046 14.3 2.2 1.1 9.7 0.7 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Glyco_hydro_77 PF02446.17 KFP06557.1 - 0.068 12.0 0.1 0.094 11.5 0.1 1.1 1 0 0 1 1 1 0 4-alpha-glucanotransferase YscO PF07321.12 KFP06557.1 - 0.073 13.0 4.3 0.13 12.2 4.3 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO UPF0242 PF06785.11 KFP06557.1 - 0.26 11.4 5.5 0.14 12.2 3.4 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DpnI_C PF17726.1 KFP06557.1 - 2.1 8.5 4.6 3.8 7.7 0.3 2.8 3 0 0 3 3 3 0 Dam-replacing HTH domain TMF_DNA_bd PF12329.8 KFP06557.1 - 3.6 7.7 7.1 2.4 8.2 4.8 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Cu-oxidase_2 PF07731.14 KFP06558.1 - 2e-30 105.3 19.7 9.2e-13 48.1 1.0 6.4 6 2 0 6 6 6 5 Multicopper oxidase Cu-oxidase_3 PF07732.15 KFP06558.1 - 2.2e-25 89.0 3.1 1.4e-07 31.6 0.0 5.5 5 0 0 5 5 5 3 Multicopper oxidase 7tm_1 PF00001.21 KFP06559.1 - 8.9e-54 182.6 27.0 9.8e-53 179.1 29.0 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP06559.1 - 2.4e-14 53.3 27.9 3.1e-14 53.0 27.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP06559.1 - 0.015 15.1 17.5 0.028 14.2 17.5 1.7 1 1 0 1 1 1 0 Olfactory receptor DUF2109 PF09882.9 KFP06559.1 - 0.52 10.4 6.7 0.43 10.6 2.4 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) 7tm_1 PF00001.21 KFP06560.1 - 5.8e-53 179.9 22.8 8.4e-53 179.4 22.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP06560.1 - 4.3e-16 59.1 21.7 5.4e-16 58.7 21.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP06560.1 - 5.6e-05 23.0 16.6 8.7e-05 22.4 16.6 1.4 1 1 0 1 1 1 1 Olfactory receptor DUF2109 PF09882.9 KFP06560.1 - 5.2 7.2 9.8 0.91 9.6 2.5 2.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2109) TNFR_c6 PF00020.18 KFP06561.1 - 6.4e-13 48.9 34.9 4.1e-08 33.5 6.1 3.7 4 0 0 4 4 4 3 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.13 KFP06561.1 - 0.0088 15.8 23.7 0.069 12.9 3.1 3.5 2 1 1 3 3 3 2 Putative ephrin-receptor like Hormone_recep PF00104.30 KFP06562.1 - 4.4e-31 108.1 2.9 6.8e-31 107.5 2.9 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFP06562.1 - 4.3e-25 88.0 14.2 7.9e-25 87.1 14.2 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) E2F_TDP PF02319.20 KFP06562.1 - 0.072 13.2 0.1 0.28 11.3 0.0 2.0 2 0 0 2 2 2 0 E2F/DP family winged-helix DNA-binding domain BAR_3 PF16746.5 KFP06563.1 - 2.1e-56 191.3 18.9 3.1e-56 190.7 18.9 1.3 1 0 0 1 1 1 1 BAR domain of APPL family RhoGAP PF00620.27 KFP06563.1 - 2.2e-41 141.2 0.1 7.2e-41 139.5 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 KFP06563.1 - 7.1e-08 32.9 1.2 9.4e-08 32.5 0.1 1.8 2 0 0 2 2 2 1 PH domain Yip1 PF04893.17 KFP06564.1 - 2.1e-18 66.6 13.0 2.1e-18 66.6 13.0 1.7 1 1 1 2 2 2 1 Yip1 domain START PF01852.19 KFP06565.1 - 1.5e-39 135.6 0.1 2.9e-39 134.7 0.1 1.4 1 0 0 1 1 1 1 START domain RhoGAP PF00620.27 KFP06565.1 - 4.9e-39 133.6 0.2 9.8e-39 132.6 0.2 1.5 1 0 0 1 1 1 1 RhoGAP domain Vault_3 PF17795.1 KFP06565.1 - 0.032 14.3 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 Major Vault Protein Repeat domain SAM_2 PF07647.17 KFP06565.1 - 0.1 12.8 0.0 0.31 11.2 0.0 1.9 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) FAM176 PF14851.6 KFP06565.1 - 4.7 6.9 9.0 1.8 8.3 4.5 2.2 2 0 0 2 2 2 0 FAM176 family LRR_8 PF13855.6 KFP06566.1 - 4.4e-44 148.1 24.2 2.8e-13 49.4 2.8 5.3 2 2 3 5 5 5 4 Leucine rich repeat 7tm_1 PF00001.21 KFP06566.1 - 2.6e-25 89.2 6.8 4.3e-25 88.5 6.8 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_5 PF13306.6 KFP06566.1 - 1.2e-17 64.0 0.0 3.7e-09 36.6 0.0 2.6 2 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP06566.1 - 3.3e-12 46.3 8.3 7.1e-07 28.9 0.1 3.6 1 1 3 4 4 4 3 Leucine-rich repeat LRR_4 PF12799.7 KFP06566.1 - 4.6e-12 46.0 27.1 0.00011 22.5 1.5 6.3 2 2 6 8 8 8 6 Leucine Rich repeats (2 copies) Ldl_recept_a PF00057.18 KFP06566.1 - 2.4e-08 34.0 3.9 2.4e-08 34.0 3.9 2.1 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A LRR_1 PF00560.33 KFP06566.1 - 6.7e-07 29.0 22.8 0.57 10.9 0.2 9.0 9 1 1 10 10 10 2 Leucine Rich Repeat LRRNT PF01462.18 KFP06566.1 - 0.0023 17.5 0.2 0.0064 16.1 0.2 1.8 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain Ephrin PF00812.17 KFP06567.1 - 2.9e-42 144.0 1.5 7.3e-42 142.6 0.1 2.0 2 0 0 2 2 2 1 Ephrin DUF4381 PF14316.6 KFP06567.1 - 0.0064 16.7 0.0 0.0096 16.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) Baculo_11_kDa PF06143.11 KFP06567.1 - 0.01 15.4 0.7 0.019 14.5 0.7 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family Shisa PF13908.6 KFP06567.1 - 0.022 15.0 0.1 0.041 14.1 0.1 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 KFP06567.1 - 0.039 14.8 0.0 0.076 13.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PalH PF08733.10 KFP06567.1 - 0.04 12.9 0.0 0.049 12.6 0.0 1.1 1 0 0 1 1 1 0 PalH/RIM21 Orthoreo_P10 PF07204.11 KFP06567.1 - 0.046 13.7 0.0 0.082 12.9 0.0 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Glucos_trans_II PF14264.6 KFP06567.1 - 0.055 12.8 0.0 0.068 12.5 0.0 1.1 1 0 0 1 1 1 0 Glucosyl transferase GtrII WBP-1 PF11669.8 KFP06567.1 - 0.062 13.9 0.1 0.17 12.5 0.0 1.7 2 0 0 2 2 1 0 WW domain-binding protein 1 Cytomega_TRL10 PF06084.11 KFP06567.1 - 0.065 13.3 0.2 0.16 12.0 0.0 1.7 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein TMEM132D_C PF15706.5 KFP06567.1 - 0.079 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term ECSCR PF15820.5 KFP06567.1 - 0.12 12.2 0.3 0.26 11.1 0.3 1.6 1 1 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Syndecan PF01034.20 KFP06567.1 - 0.15 12.0 4.7 0.26 11.2 4.7 1.3 1 0 0 1 1 1 0 Syndecan domain DUF4349 PF14257.6 KFP06567.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Stevor PF17410.2 KFP06567.1 - 0.18 11.3 0.7 0.26 10.8 0.2 1.4 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame SKG6 PF08693.10 KFP06567.1 - 1.9 7.9 5.9 5.3 6.5 5.9 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Yae1_N PF09811.9 KFP06568.1 - 1.5e-13 50.2 43.7 1.8e+04 -8.5 43.7 4.3 1 1 0 1 1 1 0 Essential protein Yae1, N terminal TNF PF00229.18 KFP06569.1 - 3.6e-09 36.6 0.4 1.7e-08 34.4 0.4 1.9 1 1 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Collagen PF01391.18 KFP06569.1 - 1.2e-07 31.3 45.1 6.6e-05 22.6 45.1 2.7 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) LRR_8 PF13855.6 KFP06570.1 - 1.2e-58 194.7 56.8 3.8e-11 42.6 1.2 10.6 6 2 3 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 KFP06570.1 - 1.7e-44 149.1 54.8 1.3e-06 28.6 0.0 11.4 9 2 2 11 11 11 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP06570.1 - 5.9e-15 53.5 66.4 0.71 10.6 0.1 19.2 17 3 1 18 18 18 5 Leucine Rich Repeat LRR_9 PF14580.6 KFP06570.1 - 5.1e-08 32.6 6.3 0.056 12.9 0.1 5.7 3 2 2 5 5 5 2 Leucine-rich repeat LRR_6 PF13516.6 KFP06570.1 - 3.1e-07 29.9 66.1 9.3 6.6 0.0 18.1 19 1 1 20 20 20 6 Leucine Rich repeat LRR_5 PF13306.6 KFP06570.1 - 2.7e-05 24.1 0.0 0.43 10.5 0.0 3.5 5 0 0 5 5 5 2 BspA type Leucine rich repeat region (6 copies) wnt PF00110.19 KFP06571.1 - 9e-110 367.1 9.9 1.1e-109 366.8 9.9 1.0 1 0 0 1 1 1 1 wnt family TAP42 PF04177.12 KFP06572.1 - 6.2e-73 245.7 0.0 7.4e-73 245.4 0.0 1.1 1 0 0 1 1 1 1 TAP42-like family PBSX_XtrA PF17356.2 KFP06572.1 - 0.068 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Phage-like element PBSX protein XtrA DUF3682 PF12446.8 KFP06572.1 - 2.1 8.8 7.2 0.88 10.0 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) DAGAT PF03982.13 KFP06573.1 - 3.5e-116 387.3 0.0 5.2e-116 386.7 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Ras PF00071.22 KFP06574.1 - 2e-55 186.8 0.4 2.5e-55 186.5 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP06574.1 - 8e-32 110.0 0.2 1.5e-31 109.1 0.2 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP06574.1 - 1.5e-12 47.3 0.5 1.7e-12 47.1 0.5 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP06574.1 - 4.3e-06 26.4 0.1 9.2e-06 25.3 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFP06574.1 - 0.001 18.5 0.1 0.0015 18.0 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFP06574.1 - 0.0087 16.1 0.1 0.014 15.4 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFP06574.1 - 0.014 14.9 0.0 0.032 13.8 0.0 1.7 1 0 0 1 1 1 0 Ferrous iron transport protein B PDZ PF00595.24 KFP06575.1 - 2.3e-17 63.1 0.2 2.7e-17 62.9 0.2 1.0 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP06575.1 - 2.7e-10 39.9 0.1 4.5e-10 39.2 0.0 1.4 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KFP06575.1 - 3.2e-08 33.8 0.0 3.4e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 PDZ domain Kinesin PF00225.23 KFP06576.1 - 7.7e-116 386.7 0.0 7.7e-116 386.7 0.0 2.9 3 1 1 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 KFP06576.1 - 2.3e-23 82.8 0.0 2.3e-23 82.8 0.0 3.8 3 0 0 3 3 3 1 Microtubule binding DUF3800 PF12686.7 KFP06576.1 - 0.81 10.3 9.1 2.1e+03 -0.7 9.1 4.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) TCR PF03638.15 KFP06576.1 - 1.3 9.4 17.5 2.8 8.3 17.5 1.6 1 0 0 1 1 1 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain TFIID-31kDa PF02291.15 KFP06577.1 - 1.2e-48 164.2 0.0 1.8e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 KFP06577.1 - 1.7e-06 28.3 0.1 3e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein Bromo_TP PF07524.13 KFP06577.1 - 3.3e-06 27.0 0.1 5.7e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 KFP06577.1 - 0.0006 20.2 0.2 0.001 19.4 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KFP06577.1 - 0.0077 16.3 0.1 0.015 15.4 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_30kDa PF03540.13 KFP06577.1 - 0.019 14.9 0.1 2.9 7.9 0.0 2.6 2 0 0 2 2 2 0 Transcription initiation factor TFIID 23-30kDa subunit TIP49_C PF17856.1 KFP06577.1 - 0.17 12.1 0.1 0.36 11.0 0.1 1.5 1 0 0 1 1 1 0 TIP49 AAA-lid domain 7tm_1 PF00001.21 KFP06578.1 - 1.4 8.2 8.4 0.04 13.2 2.3 1.5 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 KFP06579.1 - 1.3e-41 142.7 26.4 1.5e-41 142.4 26.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP06579.1 - 2e-09 37.5 24.1 3.2e-09 36.8 24.1 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Git3 PF11710.8 KFP06579.1 - 6 6.6 25.1 2.4 7.9 15.7 2.2 1 1 1 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 HMG_box_2 PF09011.10 KFP06580.1 - 2.9e-49 165.5 10.3 5.5e-30 103.8 7.3 2.3 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 KFP06580.1 - 8.8e-44 147.8 9.8 1e-27 96.3 0.1 2.4 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_5 PF14887.6 KFP06580.1 - 0.00055 19.8 11.4 0.11 12.5 1.2 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box 5 Ribosomal_60s PF00428.19 KFP06580.1 - 0.051 14.2 17.4 0.16 12.6 17.4 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein YABBY PF04690.13 KFP06580.1 - 0.8 10.3 6.3 0.25 11.9 1.1 2.4 1 1 1 2 2 2 0 YABBY protein CD99L2 PF12301.8 KFP06581.1 - 1.3e-58 198.0 1.3 1.6e-58 197.7 1.3 1.0 1 0 0 1 1 1 1 CD99 antigen like protein 2 Filament_head PF04732.14 KFP06581.1 - 0.0016 19.2 0.5 1.6 9.6 0.9 2.1 2 0 0 2 2 2 2 Intermediate filament head (DNA binding) region DUF2953 PF11167.8 KFP06581.1 - 0.17 12.0 0.1 0.28 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) ACT_7 PF13840.6 KFP06581.1 - 0.24 11.2 1.6 0.27 11.1 0.5 1.6 2 0 0 2 2 2 0 ACT domain Myotub-related PF06602.14 KFP06582.1 - 1e-149 498.3 0.0 1.3e-149 497.9 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 KFP06582.1 - 4.8e-09 36.1 0.0 8.9e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 GRAM domain DSPc PF00782.20 KFP06582.1 - 0.00098 18.9 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP06582.1 - 0.001 18.7 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFP06582.1 - 0.002 18.1 0.0 0.0035 17.4 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family 3-PAP PF12578.8 KFP06582.1 - 0.0045 16.7 0.4 0.013 15.3 0.1 1.9 2 0 0 2 2 2 1 Myotubularin-associated protein DUF4441 PF14536.6 KFP06582.1 - 0.19 12.0 1.5 0.43 10.8 1.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) Myb_CC_LHEQLE PF14379.6 KFP06582.1 - 0.64 9.8 3.8 18 5.1 1.0 2.5 2 0 0 2 2 2 0 MYB-CC type transfactor, LHEQLE motif Myotub-related PF06602.14 KFP06583.1 - 4.4e-150 499.5 0.0 6.1e-150 499.0 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 KFP06583.1 - 1.1e-19 70.4 0.0 2.2e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 GRAM domain DSPc PF00782.20 KFP06583.1 - 0.00039 20.2 0.0 0.00079 19.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP06583.1 - 0.00062 19.4 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase 3-PAP PF12578.8 KFP06583.1 - 0.0021 17.8 0.1 0.005 16.6 0.1 1.7 1 0 0 1 1 1 1 Myotubularin-associated protein Y_phosphatase3 PF13350.6 KFP06583.1 - 0.016 15.2 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family ASCH PF04266.14 KFP06584.1 - 0.033 14.8 0.0 0.053 14.1 0.0 1.3 1 1 0 1 1 1 0 ASCH domain TRCF PF03461.15 KFP06584.1 - 0.19 12.1 0.0 0.35 11.3 0.0 1.4 1 0 0 1 1 1 0 TRCF domain Tmemb_185A PF10269.9 KFP06585.1 - 5e-61 206.5 28.0 6.6e-61 206.2 28.0 1.1 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein Sulfatase PF00884.23 KFP06586.1 - 1.8e-51 175.4 0.1 2.6e-51 174.8 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFP06586.1 - 1.2e-09 38.3 0.6 1.9e-08 34.3 0.6 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KFP06586.1 - 0.0012 17.5 0.0 0.012 14.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 KFP06586.1 - 0.038 13.3 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily AF-4 PF05110.13 KFP06587.1 - 1.5e-167 560.0 80.3 1.7e-167 559.8 80.3 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein ADAM_spacer1 PF05986.14 KFP06589.1 - 5.2e-33 113.5 0.1 8.7e-33 112.8 0.1 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin PF01421.19 KFP06589.1 - 1.5e-27 96.8 0.4 2.4e-27 96.2 0.4 1.3 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 KFP06589.1 - 9.5e-20 70.9 13.9 2.3e-18 66.5 6.8 4.9 4 2 1 5 5 5 2 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 KFP06589.1 - 4.6e-16 59.6 1.9 1.1e-15 58.3 1.9 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFP06589.1 - 9.9e-11 42.2 0.3 2.8e-10 40.8 0.3 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFP06589.1 - 5.8e-10 39.4 0.5 1.2e-09 38.4 0.5 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like TSP_1 PF00090.19 KFP06589.1 - 1.1e-07 31.9 7.6 1.1e-07 31.9 7.6 7.2 8 1 0 8 8 8 2 Thrombospondin type 1 domain Pep_M12B_propep PF01562.19 KFP06589.1 - 6.3e-05 23.2 0.0 0.00022 21.5 0.0 2.0 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_4 PF13583.6 KFP06589.1 - 0.0026 17.4 0.2 0.0044 16.7 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M78 PF06114.13 KFP06589.1 - 0.085 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 IrrE N-terminal-like domain Yae1_N PF09811.9 KFP06590.1 - 2.6e-16 59.0 56.5 1.8e+04 -21.2 56.5 5.3 1 1 0 1 1 1 0 Essential protein Yae1, N terminal RRM_1 PF00076.22 KFP06591.1 - 2.1e-12 46.7 0.0 3.8e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP06591.1 - 0.0096 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF-5_eIF-2B PF01873.17 KFP06592.1 - 3.7e-41 139.7 0.5 6.5e-41 138.9 0.5 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 RXLR PF16810.5 KFP06592.1 - 0.98 9.9 4.3 1.9 9.0 4.3 1.4 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Cytochrom_c3_2 PF14537.6 KFP06592.1 - 1.2 9.6 7.3 0.092 13.2 1.3 2.2 2 1 0 2 2 2 0 Cytochrome c3 Maf1 PF09174.10 KFP06593.1 - 8.9e-64 214.8 0.0 1.2e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator zf-RanBP PF00641.18 KFP06594.1 - 4.9e-08 32.1 1.7 8.6e-08 31.4 1.7 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Cytochrom_C1 PF02167.15 KFP06595.1 - 5.5e-94 314.0 0.0 6.5e-94 313.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KFP06595.1 - 0.0069 16.7 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KFP06595.1 - 0.021 15.9 0.0 0.041 15.0 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c Gaa1 PF04114.14 KFP06596.1 - 5.8e-150 500.6 0.0 7e-150 500.3 0.0 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component FH2 PF02181.23 KFP06597.1 - 2.6e-92 309.8 12.6 3.2e-92 309.5 12.6 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain CPDase PF07823.11 KFP06597.1 - 0.039 13.6 0.5 0.084 12.6 0.5 1.5 1 1 0 1 1 1 0 Cyclic phosphodiesterase-like protein DUF1539 PF07560.11 KFP06597.1 - 0.05 13.7 1.0 0.13 12.4 1.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) FF PF01846.19 KFP06598.1 - 6.4e-47 157.5 23.7 3.5e-16 59.1 0.5 6.2 5 0 0 5 5 5 5 FF domain WW PF00397.26 KFP06598.1 - 1.9e-19 69.4 19.5 2.9e-10 40.0 8.0 2.7 2 0 0 2 2 2 2 WW domain MyTH4 PF00784.17 KFP06598.1 - 0.017 15.6 2.0 0.017 15.6 2.0 3.0 3 1 0 3 3 3 0 MyTH4 domain Glyco_hyd_101C PF17451.2 KFP06598.1 - 1.4 9.2 13.6 5.5 7.3 2.3 3.9 2 1 1 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain LUD_dom PF02589.15 KFP06598.1 - 1.8 8.3 7.2 1.5 8.5 1.2 3.0 3 0 0 3 3 3 0 LUD domain TPR_6 PF13174.6 KFP06598.1 - 5.2 7.9 5.0 30 5.5 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Glycos_transf_2 PF00535.26 KFP06599.1 - 3.5e-37 127.8 0.0 5.6e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFP06599.1 - 3.8e-29 101.5 1.1 5.9e-29 100.9 1.1 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 KFP06599.1 - 7.3e-09 35.8 0.0 1.3e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KFP06599.1 - 7.9e-06 25.4 0.1 1.6e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KFP06599.1 - 0.00013 21.6 0.0 0.00037 20.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.6 KFP06599.1 - 0.00042 21.0 0.0 0.31 11.8 0.0 2.6 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like IRK_C PF17655.1 KFP06600.1 - 2.6e-70 235.5 0.0 3.3e-70 235.2 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFP06600.1 - 2.4e-57 192.7 0.7 3.4e-57 192.2 0.7 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain DAO PF01266.24 KFP06601.1 - 3.8e-53 181.3 0.0 5.1e-53 180.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KFP06601.1 - 4.1e-41 139.8 0.1 9e-41 138.7 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase EF-hand_7 PF13499.6 KFP06601.1 - 5.5e-11 42.8 0.6 1.1e-10 41.8 0.6 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP06601.1 - 2.7e-10 39.0 0.5 0.00025 20.4 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFP06601.1 - 2.8e-09 36.1 0.4 0.00019 21.1 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain FAD_binding_2 PF00890.24 KFP06601.1 - 7.4e-08 31.9 0.2 2.8e-05 23.4 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 KFP06601.1 - 1.9e-06 27.5 0.1 1.3e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KFP06601.1 - 7e-06 25.4 0.0 0.0019 17.4 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KFP06601.1 - 3.8e-05 23.0 0.1 0.0052 16.1 0.0 3.3 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_8 PF13833.6 KFP06601.1 - 5.4e-05 23.0 0.1 0.00013 21.8 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KFP06601.1 - 0.00012 21.4 1.2 0.18 11.3 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 KFP06601.1 - 0.00076 19.8 0.0 0.002 18.4 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain HI0933_like PF03486.14 KFP06601.1 - 0.0046 15.7 0.0 0.0073 15.0 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 KFP06601.1 - 0.017 15.4 1.5 0.043 14.1 0.1 2.5 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFP06601.1 - 0.025 13.8 0.0 0.071 12.3 0.0 1.8 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KFP06601.1 - 0.036 13.3 0.0 0.23 10.7 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFP06601.1 - 0.04 13.1 0.0 0.16 11.2 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 KFP06601.1 - 0.066 13.8 0.6 0.57 10.8 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Spt5_N PF11942.8 KFP06602.1 - 0.011 16.7 6.6 0.011 16.7 6.6 1.8 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal YL1 PF05764.13 KFP06602.1 - 0.035 14.2 10.3 0.042 14.0 10.3 1.1 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.10 KFP06602.1 - 0.13 11.6 15.6 0.16 11.3 15.6 1.0 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KFP06602.1 - 0.56 8.3 13.2 0.62 8.2 13.2 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KFP06602.1 - 1.5 7.0 8.3 2 6.6 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.10 KFP06602.1 - 2.6 8.5 11.4 5.9 7.3 11.4 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Myc_N PF01056.18 KFP06602.1 - 3.1 7.6 13.2 2 8.2 11.8 1.3 1 1 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.12 KFP06602.1 - 5.8 6.1 9.8 7.1 5.9 9.8 1.3 1 0 0 1 1 1 0 NOA36 protein PDZ_6 PF17820.1 KFP06603.1 - 1.6e-10 40.6 0.0 3.2e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFP06603.1 - 1.4e-09 38.1 0.0 2.7e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP06603.1 - 6.4e-05 23.2 0.0 0.00011 22.4 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Pkinase_Tyr PF07714.17 KFP06604.1 - 3.4e-33 115.0 0.0 4.9e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP06604.1 - 3.6e-33 115.1 0.0 4.9e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.12 KFP06604.1 - 2.1e-17 62.3 0.4 5.3e-17 61.0 0.4 1.8 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.23 KFP06604.1 - 6.8e-06 27.1 15.6 6.8e-06 27.1 15.6 2.0 2 0 0 2 2 2 1 Activin types I and II receptor domain Pkinase_fungal PF17667.1 KFP06604.1 - 0.0012 17.7 0.2 0.0051 15.6 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase zf-RING_12 PF17976.1 KFP06604.1 - 0.036 14.3 2.7 0.036 14.3 2.7 2.1 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain APH PF01636.23 KFP06604.1 - 0.044 13.7 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KFP06605.1 - 1.1e-35 123.2 0.0 1.7e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP06605.1 - 1.6e-35 122.8 0.0 2.5e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.12 KFP06605.1 - 2e-17 62.4 0.4 3.5e-17 61.6 0.4 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif APH PF01636.23 KFP06605.1 - 0.002 18.1 0.1 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFP06605.1 - 0.0037 16.3 0.1 0.0079 15.2 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KFP06605.1 - 0.03 14.0 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pesticin PF16754.5 KFP06606.1 - 0.38 10.7 2.5 0.51 10.3 0.1 2.3 2 0 0 2 2 2 0 Bacterial toxin homologue of phage lysozyme, C-term Arm PF00514.23 KFP06607.1 - 5.1e-45 150.2 10.4 5.7e-10 38.9 0.0 9.1 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KFP06607.1 - 8e-07 29.4 0.2 0.013 15.8 0.0 3.1 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.22 KFP06607.1 - 5.4e-06 26.2 3.6 0.98 9.9 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 KFP06607.1 - 0.00045 20.6 1.4 1.4 9.5 0.0 4.7 4 0 0 4 4 4 1 HEAT-like repeat DAP PF15228.6 KFP06608.1 - 6.7e-12 46.4 0.7 7.9e-12 46.2 0.7 1.1 1 0 0 1 1 1 1 Death-associated protein Ank_2 PF12796.7 KFP06609.1 - 7e-53 177.2 0.5 1.4e-13 51.2 0.0 5.3 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP06609.1 - 2e-40 136.6 1.7 1.3e-07 32.0 0.0 8.3 4 2 4 8 8 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP06609.1 - 1.4e-34 114.2 0.3 0.0025 18.1 0.0 10.2 10 0 0 10 10 10 7 Ankyrin repeat Ank PF00023.30 KFP06609.1 - 2.5e-33 113.1 1.9 7.3e-05 23.0 0.0 9.3 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 KFP06609.1 - 8.3e-33 112.0 1.5 1.6e-10 41.0 0.0 7.7 3 3 5 8 8 8 5 Ankyrin repeats (many copies) TPR_2 PF07719.17 KFP06609.1 - 1.5e-07 30.9 7.0 0.25 11.6 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFP06609.1 - 1.6e-05 25.0 1.9 0.00042 20.4 0.8 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFP06609.1 - 3.9e-05 24.2 2.4 0.00072 20.1 0.0 2.8 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFP06609.1 - 0.00016 21.6 3.1 0.033 14.4 0.0 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFP06609.1 - 0.00057 19.5 5.1 1.5 8.6 0.1 3.7 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.28 KFP06609.1 - 0.0015 18.3 6.1 3.7 7.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFP06609.1 - 0.0031 18.0 3.1 0.45 11.1 0.3 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFP06609.1 - 0.0081 16.9 2.8 0.033 15.0 2.8 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFP06609.1 - 0.049 13.9 0.2 0.049 13.9 0.2 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP06609.1 - 0.071 13.2 0.3 4.7 7.5 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_16 PF13191.6 KFP06609.1 - 0.073 13.5 0.3 0.56 10.6 0.0 2.6 3 0 0 3 3 2 0 AAA ATPase domain TPR_17 PF13431.6 KFP06609.1 - 0.078 13.4 1.5 1.1 9.8 0.6 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat HJURP_mid PF12346.8 KFP06609.1 - 0.08 13.4 2.1 0.17 12.4 0.0 2.6 2 0 0 2 2 2 0 Holliday junction recognition protein-associated repeat ANAPC3 PF12895.7 KFP06609.1 - 2 8.7 4.9 0.8 10.0 1.7 2.1 2 0 0 2 2 1 0 Anaphase-promoting complex, cyclosome, subunit 3 WD40 PF00400.32 KFP06610.1 - 9.9e-45 149.6 16.5 4.7e-08 33.6 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat U-box PF04564.15 KFP06610.1 - 5.5e-27 93.8 0.2 1.3e-26 92.6 0.2 1.7 1 0 0 1 1 1 1 U-box domain SAM_2 PF07647.17 KFP06610.1 - 3.5e-13 49.5 0.2 6e-13 48.7 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) ANAPC4_WD40 PF12894.7 KFP06610.1 - 1.1e-11 44.9 0.0 0.0056 17.0 0.0 5.0 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain SAM_1 PF00536.30 KFP06610.1 - 7.1e-10 39.2 0.1 1.3e-09 38.4 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Frtz PF11768.8 KFP06610.1 - 7.8e-07 27.8 0.0 0.0084 14.5 0.0 2.8 2 1 1 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz eIF2A PF08662.11 KFP06610.1 - 1.8e-06 27.9 0.0 0.062 13.2 0.0 2.9 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFP06610.1 - 3.1e-05 23.1 1.4 0.73 8.7 0.2 3.7 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein SAM_PNT PF02198.16 KFP06610.1 - 5.4e-05 23.1 0.0 0.0002 21.3 0.0 1.9 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain zf-NOSIP PF15906.5 KFP06610.1 - 0.002 18.2 0.0 0.002 18.2 0.0 3.2 4 0 0 4 4 3 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 KFP06610.1 - 0.0027 17.5 0.6 0.0057 16.5 0.0 1.9 2 0 0 2 2 1 1 Zinc-finger of the MIZ type in Nse subunit SAM_3 PF18016.1 KFP06610.1 - 0.0054 16.5 0.2 0.021 14.6 0.2 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PALB2_WD40 PF16756.5 KFP06610.1 - 0.01 14.8 0.0 2 7.3 0.0 2.5 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Sa_NUDIX PF18167.1 KFP06610.1 - 0.14 12.0 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 SMODS-associated NUDIX domain Bromodomain PF00439.25 KFP06611.1 - 3.8e-22 78.1 0.0 1.4e-21 76.4 0.0 2.0 1 0 0 1 1 1 1 Bromodomain MBD PF01429.19 KFP06611.1 - 5.2e-14 51.7 0.2 1.4e-13 50.3 0.2 1.7 1 0 0 1 1 1 1 Methyl-CpG binding domain WSD PF15613.6 KFP06611.1 - 4.9e-13 49.4 0.2 1.3e-07 31.9 0.1 5.8 7 0 0 7 7 7 2 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD PF00628.29 KFP06611.1 - 1.1e-11 44.4 9.1 3.2e-11 42.9 9.1 1.9 1 0 0 1 1 1 1 PHD-finger DDT PF02791.17 KFP06611.1 - 1.4e-08 34.9 0.3 2.9e-08 33.9 0.3 1.6 1 0 0 1 1 1 1 DDT domain Nop14 PF04147.12 KFP06611.1 - 9.7e-07 27.4 12.2 9.7e-07 27.4 12.2 5.7 5 2 0 5 5 5 2 Nop14-like family BUD22 PF09073.10 KFP06611.1 - 0.0018 17.7 20.5 0.0018 17.7 20.5 5.7 6 0 0 6 6 6 3 BUD22 RINGv PF12906.7 KFP06612.1 - 2.4e-15 56.4 8.0 5.1e-15 55.3 8.0 1.6 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 KFP06612.1 - 0.00024 21.2 4.0 0.00024 21.2 4.0 1.8 2 0 0 2 2 2 1 FANCL C-terminal domain zf-RING_2 PF13639.6 KFP06612.1 - 0.0015 18.8 5.3 0.0031 17.8 5.3 1.6 1 0 0 1 1 1 1 Ring finger domain LRR_9 PF14580.6 KFP06613.1 - 8.9e-19 67.6 5.9 7.5e-15 54.9 2.3 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 KFP06613.1 - 4.2e-16 58.8 23.0 2.3e-05 24.6 2.0 4.7 2 2 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP06613.1 - 3.8e-10 39.4 18.2 4.6e-06 26.3 3.2 4.5 1 1 2 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 KFP06613.1 - 0.0032 17.4 10.6 0.27 11.4 0.1 4.9 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 KFP06613.1 - 0.13 12.9 13.5 54 4.9 0.2 5.7 4 2 0 4 4 4 0 Leucine Rich Repeat adh_short PF00106.25 KFP06614.1 - 5.4e-41 140.2 0.0 6.7e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP06614.1 - 4.3e-26 91.9 0.0 6e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP06614.1 - 6.2e-06 26.2 0.0 1.6e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFP06614.1 - 0.00012 21.3 0.0 0.00044 19.5 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KFP06614.1 - 0.0051 16.3 0.6 0.058 12.8 0.5 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KFP06614.1 - 0.0061 16.8 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KFP06614.1 - 0.015 15.2 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding F420_oxidored PF03807.17 KFP06614.1 - 0.053 14.1 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KFP06614.1 - 0.056 13.1 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Adenylsucc_synt PF00709.21 KFP06614.1 - 0.14 11.0 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Adenylosuccinate synthetase Peptidase_S8 PF00082.22 KFP06615.1 - 8.2e-40 136.9 0.1 1.3e-39 136.3 0.1 1.3 1 0 0 1 1 1 1 Subtilase family ABC_transp_aux PF09822.9 KFP06615.1 - 0.056 12.9 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 ABC-type uncharacterized transport system ABM PF03992.16 KFP06616.1 - 2.4e-08 34.0 0.1 5.5e-08 32.8 0.1 1.7 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase EF-hand_1 PF00036.32 KFP06616.1 - 1.2e-05 24.5 1.6 0.02 14.4 0.2 2.8 1 1 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFP06616.1 - 2.1e-05 24.1 1.6 0.029 14.3 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KFP06616.1 - 9.6e-05 22.2 1.3 0.00029 20.6 1.3 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 KFP06616.1 - 0.0002 21.7 1.4 0.0012 19.3 1.4 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KFP06616.1 - 0.0059 16.1 2.3 0.39 10.3 0.1 2.7 2 1 0 2 2 2 2 EF hand HAUS-augmin3 PF14932.6 KFP06616.1 - 0.023 14.3 1.2 0.059 12.9 0.8 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 FAM92 PF06730.11 KFP06616.1 - 0.12 11.7 0.2 0.34 10.3 0.0 1.7 2 0 0 2 2 2 0 FAM92 protein RVT_1 PF00078.27 KFP06617.1 - 0.00026 20.6 0.0 0.00047 19.8 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pyr_redox_3 PF13738.6 KFP06618.1 - 1.8e-11 43.9 0.0 1.7e-09 37.4 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFP06618.1 - 2.2e-09 37.0 0.0 1.2e-07 31.3 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFP06618.1 - 0.0093 15.1 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) AA_permease_2 PF13520.6 KFP06619.1 - 2e-65 221.3 40.8 2.4e-65 221.1 40.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFP06619.1 - 1.1e-24 86.9 32.1 1.1e-24 86.9 32.1 1.4 1 1 0 1 1 1 1 Amino acid permease Iwr1 PF08574.10 KFP06620.1 - 2e-08 35.1 13.7 2e-08 35.1 13.7 3.0 4 0 0 4 4 4 1 Transcription factor Iwr1 Exo_endo_phos PF03372.23 KFP06621.1 - 1.5e-05 24.7 0.0 0.0002 20.9 0.0 2.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CBM_6 PF03422.15 KFP06621.1 - 0.037 14.3 0.1 0.087 13.1 0.1 1.6 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) SCPU PF05229.15 KFP06621.1 - 0.18 12.2 1.7 6.1 7.3 0.0 2.7 3 0 0 3 3 3 0 Spore Coat Protein U domain LCAT PF02450.15 KFP06622.1 - 2.9e-88 296.7 1.5 3e-74 250.5 0.3 2.2 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase DUF915 PF06028.11 KFP06622.1 - 1.1e-05 24.9 0.7 0.044 13.1 0.1 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.7 KFP06622.1 - 0.0015 19.2 0.0 0.0019 18.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFP06622.1 - 0.019 14.2 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF900 PF05990.12 KFP06622.1 - 0.053 13.0 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 KFP06622.1 - 0.1 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein RRM_1 PF00076.22 KFP06623.1 - 8e-14 51.2 0.0 0.013 15.4 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RHD_dimer PF16179.5 KFP06624.1 - 1.3e-25 89.4 0.2 2.5e-25 88.4 0.2 1.5 1 0 0 1 1 1 1 Rel homology dimerisation domain RHD_DNA_bind PF00554.22 KFP06624.1 - 4.1e-24 85.4 0.6 5.2e-22 78.6 0.2 3.1 3 1 0 3 3 3 1 Rel homology DNA-binding domain TIG PF01833.24 KFP06624.1 - 8.4e-06 25.8 0.1 4.8e-05 23.4 0.1 2.5 1 1 0 1 1 1 1 IPT/TIG domain AA_permease PF00324.21 KFP06625.1 - 4.9e-63 213.4 34.6 6e-39 134.0 8.4 2.1 2 0 0 2 2 2 2 Amino acid permease SLC12 PF03522.15 KFP06625.1 - 3.1e-51 174.8 3.9 6.9e-33 114.3 1.6 2.9 1 1 1 2 2 2 2 Solute carrier family 12 SNF PF00209.18 KFP06626.1 - 5.6e-238 790.8 34.0 6.5e-238 790.6 34.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family EF-hand_1 PF00036.32 KFP06627.1 - 1.4e-18 65.0 9.8 1.3e-05 24.4 0.2 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFP06627.1 - 9.8e-18 62.5 5.4 3.8e-05 23.3 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KFP06627.1 - 1.5e-15 56.7 9.0 7.3e-07 28.9 0.1 4.1 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 KFP06627.1 - 1.7e-15 57.2 3.0 3.3e-11 43.5 0.6 3.2 2 1 0 2 2 2 2 EF-hand domain pair Acyltransferase PF01553.21 KFP06627.1 - 5.2e-12 45.5 0.0 9.9e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase EF-hand_5 PF13202.6 KFP06627.1 - 2.4e-11 42.6 10.1 0.0023 17.3 0.3 4.1 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 KFP06627.1 - 0.00085 19.2 1.5 0.65 10.0 0.0 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFP06627.1 - 0.0026 18.1 0.1 0.014 15.7 0.1 2.0 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region JmjN PF02375.17 KFP06627.1 - 0.17 11.9 0.1 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 jmjN domain Peptidase_M10 PF00413.24 KFP06628.1 - 8.7e-69 230.4 0.0 2.8e-68 228.8 0.0 1.9 1 1 0 1 1 1 1 Matrixin fn2 PF00040.19 KFP06628.1 - 1.5e-50 169.2 42.1 1.1e-17 64.0 4.3 4.1 4 0 0 4 4 4 3 Fibronectin type II domain Hemopexin PF00045.19 KFP06628.1 - 8.1e-42 140.9 9.4 7.2e-13 48.3 0.6 4.6 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 KFP06628.1 - 3e-08 33.7 0.0 7.7e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.24 KFP06628.1 - 0.014 15.0 0.0 4.1 7.0 0.0 2.5 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 KFP06628.1 - 0.026 15.0 0.0 0.05 14.1 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFP06628.1 - 0.051 13.7 0.0 0.091 12.9 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KFP06628.1 - 0.099 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 KFP06628.1 - 0.12 11.3 0.1 0.19 10.7 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Homeobox_KN PF05920.11 KFP06629.1 - 1.1e-17 63.6 0.3 1.7e-17 63.0 0.3 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFP06629.1 - 1.1e-08 34.8 1.9 1.4e-08 34.5 1.9 1.1 1 0 0 1 1 1 1 Homeodomain MRP-S32 PF10210.9 KFP06629.1 - 0.021 15.4 2.1 0.025 15.1 2.1 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 Homez PF11569.8 KFP06629.1 - 0.057 12.9 0.0 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 KFP06633.1 - 2.9e-17 62.3 0.4 4.2e-17 61.7 0.4 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFP06633.1 - 1.9e-08 34.0 0.4 2.4e-08 33.7 0.4 1.1 1 0 0 1 1 1 1 Homeodomain MRP-S32 PF10210.9 KFP06633.1 - 0.0076 16.8 1.2 0.0087 16.6 1.2 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S32 Homez PF11569.8 KFP06633.1 - 0.042 13.3 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez FTO_CTD PF12934.7 KFP06634.1 - 5.2e-09 36.1 0.3 5.6e-09 36.0 0.3 1.0 1 0 0 1 1 1 1 FTO C-terminal domain Ribosomal_L31 PF01197.18 KFP06634.1 - 0.054 13.7 0.0 0.06 13.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L31 FTO_NTD PF12933.7 KFP06635.1 - 6.9e-123 409.4 0.0 8.6e-123 409.1 0.0 1.1 1 0 0 1 1 1 1 FTO catalytic domain FTO_CTD PF12934.7 KFP06635.1 - 2e-41 141.6 4.1 3.5e-41 140.8 4.1 1.4 1 0 0 1 1 1 1 FTO C-terminal domain C2-C2_1 PF11618.8 KFP06636.1 - 8.3e-68 226.9 9.9 6.9e-57 191.5 0.2 4.8 5 0 0 5 5 5 2 First C2 domain of RPGR-interacting protein 1 RPGR1_C PF18111.1 KFP06636.1 - 3e-56 189.9 0.3 3e-56 189.9 0.3 3.6 4 0 0 4 4 4 1 Retinitis pigmentosa G-protein regulator interacting C-terminal C2 PF00168.30 KFP06636.1 - 9.7e-09 35.5 0.4 6.7e-08 32.8 0.0 2.6 2 1 1 3 3 3 1 C2 domain ATG2_CAD PF13329.6 KFP06636.1 - 0.71 9.6 5.1 1.5 8.5 4.1 2.0 1 1 1 2 2 2 0 Autophagy-related protein 2 CAD motif UQ_con PF00179.26 KFP06637.1 - 5.3e-23 81.2 0.0 8.7e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RB_A PF01858.17 KFP06638.1 - 6.6e-73 244.8 0.6 1.6e-71 240.2 0.3 2.4 2 0 0 2 2 2 1 Retinoblastoma-associated protein A domain RB_B PF01857.20 KFP06638.1 - 1.1e-57 193.7 0.0 5.4e-57 191.5 0.0 2.3 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 KFP06638.1 - 2.4e-48 163.2 0.1 2.4e-48 163.2 0.1 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3452) DUF4128 PF13554.6 KFP06638.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function Imm-NTF2 PF15655.6 KFP06638.1 - 0.13 12.5 0.7 0.27 11.5 0.3 1.8 2 0 0 2 2 2 0 NTF2 fold immunity protein SPATA3 PF15662.5 KFP06638.1 - 4.6 7.8 13.3 7.3 7.2 7.4 2.5 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family DUF4317 PF14199.6 KFP06639.1 - 0.1 11.7 0.4 0.096 11.8 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4317) HMG_box PF00505.19 KFP06640.1 - 6.4e-18 64.9 0.3 1.8e-17 63.5 0.3 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP06640.1 - 7.8e-12 45.6 0.5 7.8e-12 45.6 0.5 2.4 2 1 0 2 2 2 1 HMG-box domain PA-IL PF07828.12 KFP06640.1 - 0.066 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 PA-IL-like protein IMUP PF15761.5 KFP06640.1 - 0.29 11.8 12.4 0.15 12.7 9.0 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein MgsA_C PF12002.8 KFP06640.1 - 1.1 9.2 10.7 11 5.9 11.6 2.1 2 0 0 2 2 2 0 MgsA AAA+ ATPase C terminal zf-C2H2 PF00096.26 KFP06641.1 - 2.8e-34 115.6 72.9 1.4e-05 25.2 0.2 10.1 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP06641.1 - 4.8e-34 114.1 72.3 8.7e-05 23.0 0.4 10.6 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP06641.1 - 1.4e-25 89.0 39.5 0.00017 21.7 1.4 9.4 9 0 0 9 9 9 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP06641.1 - 4.5e-25 87.2 52.2 0.001 19.4 0.6 9.8 9 0 0 9 9 9 8 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KFP06641.1 - 7.3e-25 86.3 66.5 4.9e-07 29.9 1.1 11.6 12 0 0 12 12 12 5 Zinc-finger double domain zf-C2H2_6 PF13912.6 KFP06641.1 - 6.6e-08 32.4 67.9 0.12 12.4 2.0 9.7 10 0 0 10 10 9 7 C2H2-type zinc finger IZUMO PF15005.6 KFP06641.1 - 0.00065 20.2 0.2 0.11 13.0 0.0 2.8 2 0 0 2 2 2 1 Izumo sperm-egg fusion, Ig domain-associated BolA PF01722.18 KFP06641.1 - 0.01 16.1 9.9 1.9 8.8 0.0 5.1 5 0 0 5 5 5 0 BolA-like protein DUF3268 PF11672.8 KFP06641.1 - 0.011 16.1 17.3 0.39 11.1 0.3 4.3 4 0 0 4 4 4 0 zinc-finger-containing domain zf-C2H2_9 PF16293.5 KFP06641.1 - 0.041 13.7 5.6 7.7 6.4 0.2 4.8 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 KFP06641.1 - 0.044 14.1 47.0 1.1 9.6 0.9 9.1 5 4 5 10 10 9 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 KFP06641.1 - 0.12 12.7 41.2 0.035 14.4 2.3 5.2 6 0 0 6 6 4 0 Drought induced 19 protein (Di19), zinc-binding Hexapep PF00132.24 KFP06641.1 - 0.14 11.9 0.2 0.35 10.7 0.2 1.6 1 0 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) zf-C2HC_2 PF13913.6 KFP06641.1 - 0.15 12.0 44.2 0.58 10.1 0.1 8.3 9 0 0 9 9 8 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KFP06641.1 - 0.67 9.8 0.0 0.67 9.8 0.0 8.9 10 0 0 10 10 8 0 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 KFP06641.1 - 0.86 9.9 29.9 0.32 11.3 1.1 5.7 6 1 0 6 6 5 0 C2H2-type zinc ribbon zf_C2HC_14 PF18574.1 KFP06641.1 - 6.2 6.7 6.6 1.9 8.4 1.5 2.8 2 0 0 2 2 2 0 C2HC Zing finger domain PX PF00787.24 KFP06642.1 - 6.1e-16 58.4 5.7 2.5e-15 56.5 3.7 2.6 3 0 0 3 3 3 1 PX domain TPR_12 PF13424.6 KFP06642.1 - 0.0097 16.2 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat Ocnus PF05005.15 KFP06642.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Janus/Ocnus family (Ocnus) EF-hand_7 PF13499.6 KFP06643.1 - 0.0013 19.2 0.1 0.0039 17.6 0.1 2.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP06643.1 - 0.003 17.4 0.0 0.007 16.2 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KFP06643.1 - 0.01 15.3 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 0 EF hand Nitroreductase PF00881.24 KFP06643.1 - 0.017 15.2 0.2 0.19 11.8 0.0 2.2 2 0 0 2 2 2 0 Nitroreductase family DUF3512 PF12024.8 KFP06644.1 - 1.8e-83 279.7 0.1 1.8e-83 279.7 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3512) Bromodomain PF00439.25 KFP06644.1 - 9.3e-22 76.9 1.6 2.1e-21 75.7 1.6 1.7 1 0 0 1 1 1 1 Bromodomain Med24_N PF11277.8 KFP06644.1 - 1.1 7.2 5.1 0.37 8.8 2.5 1.4 1 1 0 1 1 1 0 Mediator complex subunit 24 N-terminal DUF2796 PF10986.8 KFP06644.1 - 5.1 7.0 12.2 0.041 13.9 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) NTP_transf_2 PF01909.23 KFP06645.1 - 1.8e-16 60.2 0.1 4.4e-16 58.9 0.1 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 KFP06645.1 - 4.8e-15 55.5 0.1 1.5e-14 53.9 0.0 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase Polbeta PF18765.1 KFP06645.1 - 0.00052 20.0 0.0 0.0013 18.8 0.0 1.8 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase HEAT_EZ PF13513.6 KFP06646.1 - 1.3e-08 35.2 2.7 1.6e-06 28.5 0.4 4.4 3 1 1 4 4 4 1 HEAT-like repeat HEAT_2 PF13646.6 KFP06646.1 - 3.8e-06 27.2 0.3 0.0094 16.3 0.0 3.4 2 1 0 2 2 2 2 HEAT repeats HEAT PF02985.22 KFP06646.1 - 1.3e-05 25.0 8.9 0.43 11.0 0.2 5.6 5 0 0 5 5 5 2 HEAT repeat Arm PF00514.23 KFP06646.1 - 0.0061 16.6 0.1 0.0061 16.6 0.1 5.6 9 0 0 9 9 9 1 Armadillo/beta-catenin-like repeat TAF6_C PF07571.13 KFP06646.1 - 0.025 14.9 0.0 0.17 12.3 0.0 2.5 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain Cnd1 PF12717.7 KFP06646.1 - 0.1 12.6 1.9 0.32 11.0 0.2 2.7 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Tmemb_18A PF09771.9 KFP06647.1 - 2.8e-56 189.0 0.1 3.1e-56 188.9 0.1 1.0 1 0 0 1 1 1 1 Transmembrane protein 188 DUF418 PF04235.12 KFP06647.1 - 0.029 14.3 0.2 0.032 14.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF418) DUF35_N PF12172.8 KFP06647.1 - 0.1 12.5 0.0 6.3 6.8 0.0 3.1 4 0 0 4 4 4 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF5392 PF17370.2 KFP06647.1 - 0.19 11.8 0.1 0.23 11.5 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5392) zf-C2H2_4 PF13894.6 KFP06648.1 - 3e-69 223.6 216.0 0.00039 21.0 1.7 31.2 31 0 0 31 31 31 28 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP06648.1 - 2.9e-58 191.2 215.6 0.00032 21.0 1.4 30.9 31 0 0 31 31 31 22 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP06648.1 - 2.4e-26 91.0 186.1 0.00029 21.1 2.9 29.9 30 0 0 30 30 30 14 Zinc-finger double domain zf-Di19 PF05605.12 KFP06648.1 - 3.7e-23 81.6 186.7 0.00028 21.1 2.6 19.8 17 4 6 23 23 23 13 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KFP06648.1 - 7.1e-22 76.9 169.5 1.5e-05 24.8 0.9 26.3 26 1 1 27 27 27 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP06648.1 - 1.9e-17 63.0 171.1 0.0098 16.2 0.8 27.3 27 2 1 28 28 28 13 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 KFP06648.1 - 4.5e-05 24.1 115.2 0.00099 19.8 7.7 16.9 8 5 5 14 14 14 4 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 KFP06648.1 - 0.00027 21.2 176.4 0.68 10.3 6.5 24.7 7 5 8 17 17 16 7 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFP06648.1 - 0.00037 20.8 15.8 0.0024 18.2 2.1 22.9 28 0 0 28 28 27 8 Zinc-finger of C2H2 type C1_4 PF07975.12 KFP06648.1 - 0.029 14.6 0.8 0.029 14.6 0.8 19.5 14 3 8 23 23 22 0 TFIIH C1-like domain zf-C2H2_9 PF16293.5 KFP06648.1 - 0.09 12.6 0.1 0.09 12.6 0.1 17.4 17 4 4 21 21 21 0 C2H2 type zinc-finger (1 copy) Zn-C2H2_12 PF18112.1 KFP06648.1 - 0.11 13.0 0.2 0.11 13.0 0.2 14.4 15 0 0 15 15 14 0 Autophagy receptor zinc finger-C2H2 domain zf-C2HE PF16278.5 KFP06648.1 - 0.55 10.7 0.0 0.11 12.9 0.6 21.6 14 5 9 23 23 21 0 C2HE / C2H2 / C2HC zinc-binding finger C1q PF00386.21 KFP06649.1 - 1.4e-20 73.7 0.1 1.6e-20 73.6 0.1 1.0 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 KFP06649.1 - 0.027 14.4 0.0 0.03 14.2 0.0 1.1 1 0 0 1 1 1 0 BclA C-terminal domain RNase_Zc3h12a PF11977.8 KFP06650.1 - 6.7e-54 181.9 0.0 2.3e-53 180.2 0.0 1.9 2 0 0 2 2 2 1 Zc3h12a-like Ribonuclease NYN domain UBA_6 PF18039.1 KFP06650.1 - 0.023 14.6 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain DUF4392 PF14336.6 KFP06650.1 - 0.074 12.5 0.0 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) Sina PF03145.16 KFP06651.1 - 1.3e-88 296.2 0.1 2e-88 295.6 0.1 1.2 1 0 0 1 1 1 1 Seven in absentia protein family Lon_C PF05362.13 KFP06652.1 - 1.5e-79 266.4 0.0 2.3e-79 265.7 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 KFP06652.1 - 1e-21 77.8 0.0 3.2e-21 76.1 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 KFP06652.1 - 3.8e-15 56.3 0.2 3.8e-15 56.3 0.2 1.7 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA_5 PF07728.14 KFP06652.1 - 5.7e-09 36.1 0.0 1.6e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFP06652.1 - 4.4e-05 23.9 0.1 0.00042 20.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain ChlI PF13541.6 KFP06652.1 - 7.6e-05 22.6 0.0 0.00018 21.3 0.0 1.7 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_3 PF07726.11 KFP06652.1 - 0.00031 20.6 0.0 0.00079 19.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFP06652.1 - 0.0015 18.8 0.1 0.023 15.0 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.11 KFP06652.1 - 0.0018 17.3 0.0 0.018 13.9 0.0 2.1 2 0 0 2 2 2 1 PrkA AAA domain AAA_2 PF07724.14 KFP06652.1 - 0.0026 17.9 0.0 0.0078 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RsgA_GTPase PF03193.16 KFP06652.1 - 0.0049 16.8 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 KFP06652.1 - 0.0071 16.9 0.0 0.026 15.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KFP06652.1 - 0.011 15.5 0.0 0.039 13.7 0.0 1.9 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KFP06652.1 - 0.023 14.5 0.1 0.068 12.9 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.15 KFP06652.1 - 0.029 14.3 0.0 0.065 13.2 0.0 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain SKI PF01202.22 KFP06652.1 - 0.036 14.2 0.5 0.089 12.9 0.0 1.9 2 0 0 2 2 2 0 Shikimate kinase AAA_33 PF13671.6 KFP06652.1 - 0.048 13.8 0.5 0.27 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFP06652.1 - 0.14 12.5 0.0 0.35 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Sld5 PF05916.11 KFP06652.1 - 0.54 10.7 7.6 1 9.8 0.6 2.6 2 0 0 2 2 2 0 GINS complex protein Glyco_hydro_15 PF00723.21 KFP06653.1 - 6.4e-108 361.4 0.0 8.3e-108 361.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 VCBS PF13517.6 KFP06654.1 - 7.5e-18 64.9 12.5 8.7e-05 23.0 2.4 5.5 3 1 3 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KFP06654.1 - 9e-09 35.3 10.6 0.023 14.8 0.1 5.7 6 0 0 6 6 6 4 FG-GAP repeat Phage_holin_2_4 PF16082.5 KFP06654.1 - 0.15 11.8 0.1 0.28 10.9 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like K1 PF02960.14 KFP06654.1 - 0.16 12.1 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 K1 glycoprotein CUB PF00431.20 KFP06655.1 - 1.4e-41 141.2 0.2 7.1e-27 93.9 0.0 3.0 3 0 0 3 3 3 2 CUB domain Ldl_recept_a PF00057.18 KFP06655.1 - 1.5e-06 28.3 3.4 1.5e-06 28.3 3.4 2.4 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A DnaJ_C PF01556.18 KFP06656.1 - 9.4e-45 152.3 0.2 1.3e-44 151.9 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFP06656.1 - 4.1e-16 58.9 1.0 7.6e-16 58.0 1.0 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KFP06656.1 - 3.6e-08 33.7 11.0 7.3e-08 32.7 11.0 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KFP06656.1 - 0.57 10.2 9.6 0.41 10.6 1.6 2.9 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Borealin PF10512.9 KFP06657.1 - 1.3e-08 34.9 0.1 1.5e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 Cell division cycle-associated protein 8 Marek_A PF02124.15 KFP06657.1 - 0.024 14.5 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 Marek's disease glycoprotein A Aminotran_1_2 PF00155.21 KFP06658.1 - 1.4e-32 113.3 0.0 1.7e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II UPF0547 PF10571.9 KFP06659.1 - 1.8e-05 24.7 2.8 2.7e-05 24.1 2.8 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 Zip PF02535.22 KFP06659.1 - 0.25 10.5 2.3 0.28 10.4 2.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Sec62 PF03839.16 KFP06659.1 - 0.45 10.0 4.3 0.5 9.8 4.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 RAM PF15320.6 KFP06659.1 - 0.61 10.7 8.3 0.94 10.1 8.3 1.2 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein Presenilin PF01080.17 KFP06659.1 - 1.1 7.9 5.8 1.2 7.8 5.8 1.0 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 KFP06659.1 - 2.5 8.1 4.6 2.9 7.9 4.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pkinase PF00069.25 KFP06660.1 - 1.3e-21 77.2 0.0 1.5e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP06660.1 - 1.1e-05 24.9 0.0 1.5e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Vps35 PF03635.17 KFP06661.1 - 1e-301 1002.8 13.4 1.2e-301 1002.6 13.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 FerA PF08165.11 KFP06661.1 - 0.022 14.7 0.2 0.12 12.4 0.2 2.2 1 0 0 1 1 1 0 FerA (NUC095) domain 7tm_1 PF00001.21 KFP06662.1 - 3.6e-63 213.4 8.7 4.4e-63 213.1 8.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP06662.1 - 5.2e-08 32.6 15.5 9.9e-06 25.1 8.2 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP06662.1 - 3.8e-05 23.5 8.9 3.8e-05 23.5 8.9 2.0 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP06662.1 - 0.012 15.3 9.3 0.011 15.5 5.0 2.1 2 0 0 2 2 2 0 Olfactory receptor Beta_helix PF13229.6 KFP06663.1 - 8.4e-11 42.0 0.4 1.6e-10 41.0 0.4 1.4 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 KFP06663.1 - 4.6e-07 29.4 0.0 8.1e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Hormone_recep PF00104.30 KFP06664.1 - 3.5e-40 137.8 0.0 4.7e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DHHC PF01529.20 KFP06665.1 - 3.3e-36 124.3 13.4 3.3e-36 124.3 13.4 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF3615 PF12274.8 KFP06665.1 - 0.29 11.7 4.1 0.62 10.6 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3615) TRIQK PF15168.6 KFP06665.1 - 0.32 10.9 3.2 4.5 7.2 0.1 2.6 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family DUF4191 PF13829.6 KFP06665.1 - 4.5 6.6 4.5 5.4 6.3 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Forkhead PF00250.18 KFP06668.1 - 3.4e-39 133.0 0.0 3.8e-39 132.8 0.0 1.0 1 0 0 1 1 1 1 Forkhead domain Forkhead PF00250.18 KFP06669.1 - 1.6e-40 137.2 0.1 2.8e-40 136.5 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain 5-FTHF_cyc-lig PF01812.20 KFP06670.1 - 7.2e-25 87.9 0.0 1.1e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family RRM_1 PF00076.22 KFP06670.1 - 2.7e-05 23.9 0.0 7.1e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Forkhead PF00250.18 KFP06671.1 - 5.6e-38 129.1 0.0 2e-37 127.3 0.0 1.9 2 0 0 2 2 2 1 Forkhead domain Ig_3 PF13927.6 KFP06672.1 - 1.6e-80 265.8 7.9 3.5e-15 56.4 0.0 7.4 7 0 0 7 7 7 6 Immunoglobulin domain I-set PF07679.16 KFP06672.1 - 7.1e-77 253.6 0.0 1.9e-13 50.3 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin I-set domain ig PF00047.25 KFP06672.1 - 6.6e-58 192.9 1.0 1.9e-10 40.8 0.0 7.1 7 0 0 7 7 7 6 Immunoglobulin domain Ig_2 PF13895.6 KFP06672.1 - 3.5e-54 181.1 7.1 3.8e-09 36.8 0.0 7.5 7 0 0 7 7 7 6 Immunoglobulin domain fn3 PF00041.21 KFP06672.1 - 3.6e-32 110.5 15.3 3e-10 40.3 0.5 4.7 4 0 0 4 4 4 4 Fibronectin type III domain V-set PF07686.17 KFP06672.1 - 3.8e-30 104.3 11.1 0.00047 20.3 0.0 11.5 7 5 2 9 9 9 5 Immunoglobulin V-set domain Ig_6 PF18452.1 KFP06672.1 - 3.1e-14 52.3 0.0 0.14 11.8 0.0 6.5 6 0 0 6 6 6 4 Immunoglobulin domain Ig_5 PF16681.5 KFP06672.1 - 2.7e-11 43.7 0.0 0.51 10.8 0.0 6.8 7 0 0 7 7 7 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFP06672.1 - 7.6e-09 35.7 0.0 0.12 12.7 0.0 6.0 6 0 0 6 6 6 1 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFP06672.1 - 5.3e-08 32.8 0.3 0.93 9.6 0.0 5.6 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 KFP06672.1 - 4.9e-06 26.5 0.4 8.8 6.4 0.0 5.7 6 0 0 6 6 6 1 C17orf99 Ig domain Tissue_fac PF01108.17 KFP06672.1 - 4.4e-05 23.3 2.2 0.018 14.9 0.3 3.1 2 1 1 3 3 3 2 Tissue factor C2-set PF05790.15 KFP06672.1 - 0.0077 16.4 0.1 39 4.5 0.0 5.5 5 1 1 6 6 6 0 Immunoglobulin C2-set domain fn3_4 PF16794.5 KFP06672.1 - 0.0095 15.9 0.6 0.34 10.8 0.2 3.1 3 0 0 3 3 3 1 Fibronectin-III type domain Interfer-bind PF09294.10 KFP06672.1 - 0.017 15.4 0.1 9.7 6.6 0.0 3.2 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III Pur_ac_phosph_N PF16656.5 KFP06672.1 - 0.028 15.0 3.4 8.9 7.0 0.0 3.4 3 0 0 3 3 2 0 Purple acid Phosphatase, N-terminal domain Ig_3 PF13927.6 KFP06673.1 - 9.5e-74 244.0 8.5 1.2e-14 54.6 0.0 7.4 8 1 0 8 8 7 6 Immunoglobulin domain I-set PF07679.16 KFP06673.1 - 4.9e-69 228.5 0.0 7.9e-14 51.5 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin I-set domain ig PF00047.25 KFP06673.1 - 3.5e-53 177.7 3.8 2.9e-10 40.2 0.0 7.0 7 0 0 7 7 7 6 Immunoglobulin domain Ig_2 PF13895.6 KFP06673.1 - 1.1e-47 160.3 0.0 3e-08 33.9 0.0 6.8 5 1 1 6 6 6 6 Immunoglobulin domain fn3 PF00041.21 KFP06673.1 - 4.4e-42 142.3 13.9 9e-15 54.8 0.4 4.5 4 0 0 4 4 4 4 Fibronectin type III domain V-set PF07686.17 KFP06673.1 - 1.4e-30 105.6 10.3 7.2e-05 22.9 0.1 11.0 6 5 0 6 6 6 5 Immunoglobulin V-set domain Ig_6 PF18452.1 KFP06673.1 - 9.3e-18 63.5 0.0 0.044 13.4 0.0 6.3 6 0 0 6 6 6 5 Immunoglobulin domain Ig_5 PF16681.5 KFP06673.1 - 1.2e-11 44.8 0.0 0.024 15.0 0.0 7.1 7 1 0 7 7 7 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 KFP06673.1 - 2.4e-10 40.3 0.0 0.95 9.5 0.0 5.8 6 0 0 6 6 6 3 C17orf99 Ig domain Izumo-Ig PF16706.5 KFP06673.1 - 3.3e-10 39.9 0.0 3.7 7.7 0.0 6.4 6 0 0 6 6 6 3 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 KFP06673.1 - 4.7e-07 30.0 0.0 1.8 8.9 0.0 5.7 6 0 0 6 6 6 1 T-cell surface glycoprotein CD3 delta chain V-set_CD47 PF08204.11 KFP06673.1 - 2.7e-05 24.2 0.8 12 5.9 0.1 4.8 4 0 0 4 4 4 0 CD47 immunoglobulin-like domain C2-set_2 PF08205.12 KFP06673.1 - 9.2e-05 22.4 0.1 0.39 10.8 0.0 3.7 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Tissue_fac PF01108.17 KFP06673.1 - 0.00047 20.0 2.1 0.24 11.3 0.2 3.2 3 0 0 3 3 3 2 Tissue factor Herpes_gE PF02480.16 KFP06673.1 - 0.0018 17.1 0.0 7.6 5.2 0.0 4.3 5 0 0 5 5 5 1 Alphaherpesvirus glycoprotein E fn3_4 PF16794.5 KFP06673.1 - 0.0026 17.6 0.1 3.4 7.6 0.0 3.2 3 0 0 3 3 3 1 Fibronectin-III type domain fn3_2 PF16893.5 KFP06673.1 - 0.0034 17.5 0.2 4.5 7.5 0.0 3.4 3 0 0 3 3 3 1 Fibronectin type III domain Adeno_E3_CR1 PF02440.15 KFP06673.1 - 0.0047 16.7 0.4 12 5.8 0.0 4.3 4 0 0 4 4 4 0 Adenovirus E3 region protein CR1 Pur_ac_phosph_N PF16656.5 KFP06673.1 - 0.02 15.4 9.3 0.13 12.8 0.0 3.9 3 1 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain IL6Ra-bind PF09240.10 KFP06674.1 - 1.3e-23 83.2 0.4 5.9e-23 81.1 0.2 2.0 2 0 0 2 2 2 1 Interleukin-6 receptor alpha chain, binding Tissue_fac PF01108.17 KFP06674.1 - 2.8e-07 30.4 4.3 0.012 15.5 0.1 3.4 3 1 0 3 3 3 3 Tissue factor Il13Ra_Ig PF18001.1 KFP06674.1 - 0.0073 16.4 0.4 0.14 12.3 0.0 2.8 3 0 0 3 3 3 1 Interleukin-13 receptor subunit alpha Ig-like domain fn3 PF00041.21 KFP06674.1 - 0.016 15.5 3.1 1.1 9.7 0.1 3.1 3 1 0 3 3 3 0 Fibronectin type III domain EpoR_lig-bind PF09067.10 KFP06674.1 - 0.027 14.7 1.2 0.081 13.1 1.2 1.8 1 0 0 1 1 1 0 Erythropoietin receptor, ligand binding PolyA_pol PF01743.20 KFP06675.1 - 8.2e-33 113.5 0.3 1.3e-32 112.9 0.3 1.3 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KFP06675.1 - 3.2e-13 49.2 0.1 3e-12 46.1 0.0 2.3 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A LON_substr_bdg PF02190.16 KFP06676.1 - 2.1e-24 86.6 0.0 2.7e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Yippee-Mis18 PF03226.14 KFP06676.1 - 1.6e-11 44.4 0.2 3e-11 43.5 0.2 1.5 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Baculo_ME53 PF06061.11 KFP06676.1 - 0.14 11.4 2.3 0.24 10.6 2.3 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 LRR_8 PF13855.6 KFP06677.1 - 3.1e-51 171.0 68.4 1.9e-13 50.0 3.3 6.1 1 1 6 7 7 7 7 Leucine rich repeat LRR_5 PF13306.6 KFP06677.1 - 8.6e-25 87.2 1.0 1.1e-11 44.8 3.1 3.9 2 1 2 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFP06677.1 - 1.9e-24 85.3 48.1 3.3e-06 27.3 1.7 8.7 4 1 2 9 9 9 6 Leucine Rich repeats (2 copies) I-set PF07679.16 KFP06677.1 - 2.5e-16 59.5 0.1 1.4e-15 57.1 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain LRR_9 PF14580.6 KFP06677.1 - 4.2e-13 49.2 25.0 0.00026 20.6 3.5 4.4 1 1 3 4 4 4 4 Leucine-rich repeat Ig_3 PF13927.6 KFP06677.1 - 9.5e-13 48.6 0.0 2.9e-12 47.0 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP06677.1 - 1.3e-07 31.7 0.1 1.5e-06 28.3 0.0 2.6 3 0 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 KFP06677.1 - 1.7e-06 28.3 0.0 1.2e-05 25.6 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFP06677.1 - 1.1e-05 25.5 0.2 0.00022 21.4 0.0 2.9 2 1 0 2 2 2 1 Immunoglobulin V-set domain LRRCT PF01463.24 KFP06677.1 - 6.4e-05 23.2 0.1 0.00017 21.9 0.1 1.8 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain LRR_1 PF00560.33 KFP06677.1 - 0.00013 22.0 27.2 0.078 13.6 0.2 9.4 10 0 0 10 10 9 1 Leucine Rich Repeat LRRNT PF01462.18 KFP06677.1 - 0.00024 20.6 1.0 0.00024 20.6 1.0 2.2 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain Ig_6 PF18452.1 KFP06677.1 - 0.0011 18.5 0.0 0.0079 15.7 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFP06677.1 - 0.0022 18.5 1.3 0.0085 16.6 1.3 2.0 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain fn3 PF00041.21 KFP06677.1 - 0.0023 18.3 1.1 0.0052 17.1 1.1 1.6 1 0 0 1 1 1 1 Fibronectin type III domain LRR_6 PF13516.6 KFP06677.1 - 0.027 14.5 16.0 15 6.0 0.1 6.7 4 1 1 5 5 5 0 Leucine Rich repeat Ig_5 PF16681.5 KFP06677.1 - 0.045 14.1 0.0 0.15 12.4 0.0 1.9 1 0 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain SET PF00856.28 KFP06678.1 - 3.9e-21 76.2 0.1 2.1e-19 70.5 0.1 2.2 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 KFP06678.1 - 5.4e-07 30.2 9.6 5.4e-07 30.2 9.6 1.9 2 0 0 2 2 2 1 Pre-SET motif AWS PF17907.1 KFP06678.1 - 0.0016 18.5 4.3 0.0016 18.5 4.3 2.8 3 1 0 3 3 3 1 AWS domain FGE-sulfatase PF03781.16 KFP06679.1 - 4e-87 292.1 5.8 4.5e-87 291.9 5.8 1.0 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Ins145_P3_rec PF08709.11 KFP06680.1 - 2.3e-95 317.8 0.0 1.9e-94 314.8 0.0 2.4 2 0 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RYDR_ITPR PF01365.21 KFP06680.1 - 4e-72 241.9 26.4 1.1e-61 207.9 0.5 5.4 6 0 0 6 6 6 2 RIH domain MIR PF02815.19 KFP06680.1 - 4.5e-71 238.5 0.1 8.6e-68 227.8 0.0 2.6 2 0 0 2 2 2 2 MIR domain RIH_assoc PF08454.11 KFP06680.1 - 3.8e-31 106.9 6.9 3.8e-31 106.9 6.9 6.3 6 2 0 6 6 6 2 RyR and IP3R Homology associated Ion_trans PF00520.31 KFP06680.1 - 3.4e-14 52.7 9.4 3.4e-14 52.7 9.4 2.0 2 0 0 2 2 2 1 Ion transport protein Plk4_PB2 PF18409.1 KFP06680.1 - 1 10.1 3.9 0.94 10.2 0.1 3.0 3 0 0 3 3 3 0 Polo-like Kinase 4 Polo Box 2 Hairy_orange PF07527.13 KFP06681.1 - 6.7e-11 42.2 0.3 1.6e-10 41.0 0.3 1.7 1 0 0 1 1 1 1 Hairy Orange Arf PF00025.21 KFP06682.1 - 1.1e-39 135.7 0.1 1.3e-39 135.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFP06682.1 - 5.6e-15 55.3 0.0 6.2e-15 55.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP06682.1 - 4.8e-11 42.9 0.0 7.3e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KFP06682.1 - 1e-06 28.3 0.0 1.2e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KFP06682.1 - 1.5e-05 24.4 0.1 2e-05 24.0 0.1 1.4 1 1 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.10 KFP06682.1 - 0.005 16.3 0.0 0.0056 16.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFP06682.1 - 0.012 15.6 0.0 0.026 14.6 0.0 1.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Glyco_hydro_47 PF01532.20 KFP06683.1 - 9.8e-123 410.4 0.0 1.7e-122 409.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 DUF2063 PF09836.9 KFP06683.1 - 0.14 12.5 0.0 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 Putative DNA-binding domain ANF_receptor PF01094.28 KFP06685.1 - 6.3e-104 347.9 0.0 8.8e-104 347.4 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 KFP06685.1 - 3.5e-61 207.0 14.3 4.9e-61 206.5 14.3 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 KFP06685.1 - 5.7e-13 48.6 11.1 1.2e-12 47.6 11.1 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.6 KFP06685.1 - 1.2e-09 38.3 0.1 3.8e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 Periplasmic binding protein Caveolin PF01146.17 KFP06686.1 - 2.2e-59 199.2 1.9 2.5e-59 199.0 1.9 1.0 1 0 0 1 1 1 1 Caveolin 7tm_1 PF00001.21 KFP06687.1 - 3.1e-39 134.9 13.7 3.5e-39 134.7 13.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP06687.1 - 0.0021 17.5 12.3 0.0031 16.9 12.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Comm PF15957.5 KFP06687.1 - 7.4 7.0 9.3 4.9 7.5 0.5 2.4 1 1 1 2 2 2 0 Commissureless SAP PF02037.27 KFP06688.1 - 3.5e-09 36.2 0.2 7.3e-09 35.2 0.2 1.6 1 0 0 1 1 1 1 SAP domain zf-C3HC4_2 PF13923.6 KFP06688.1 - 6.2e-09 35.6 8.8 6.2e-09 35.6 8.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP06688.1 - 4.6e-07 29.6 10.2 4.6e-07 29.6 10.2 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KFP06688.1 - 1.3e-06 28.2 8.8 1.7e-06 27.8 5.1 2.4 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 KFP06688.1 - 0.00014 21.6 16.0 0.00015 21.5 9.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP06688.1 - 0.00017 21.9 12.4 0.00017 21.9 12.4 2.8 3 0 0 3 3 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KFP06688.1 - 0.0018 18.3 10.4 0.0018 18.3 10.4 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP06688.1 - 0.0025 17.7 13.3 0.0025 17.7 13.3 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-WRNIP1_ubi PF18279.1 KFP06688.1 - 0.011 16.3 4.6 0.024 15.3 0.0 3.0 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-rbx1 PF12678.7 KFP06688.1 - 0.018 15.3 12.0 0.021 15.1 8.1 3.0 2 1 0 2 2 2 0 RING-H2 zinc finger domain YafQ_toxin PF15738.5 KFP06688.1 - 0.043 14.1 0.5 0.13 12.6 0.5 1.9 1 0 0 1 1 1 0 Bacterial toxin of type II toxin-antitoxin system, YafQ LEM PF03020.15 KFP06688.1 - 0.1 12.2 0.2 0.21 11.2 0.2 1.5 1 0 0 1 1 1 0 LEM domain zf-RING_10 PF16685.5 KFP06688.1 - 0.13 12.4 15.3 0.04 14.0 5.5 3.0 3 0 0 3 3 3 0 zinc RING finger of MSL2 Hydin_ADK PF17213.3 KFP06688.1 - 0.49 10.6 7.2 0.093 13.0 2.6 2.1 1 1 2 3 3 3 0 Hydin Adenylate kinase-like domain GAT PF03127.14 KFP06688.1 - 0.52 10.7 3.5 0.59 10.5 0.0 2.7 3 1 0 3 3 3 0 GAT domain SPT16 PF08644.11 KFP06688.1 - 1.6 8.9 7.5 1 9.5 5.2 1.9 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) zf-C3HC4_4 PF15227.6 KFP06688.1 - 6.8 6.9 21.0 0.88 9.8 15.2 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RhoGAP PF00620.27 KFP06689.1 - 6.3e-48 162.4 0.0 2.3e-47 160.7 0.0 2.0 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 KFP06689.1 - 1.3e-18 67.0 5.0 1.3e-18 67.0 5.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KFP06689.1 - 5.9e-10 38.6 0.0 2.3e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFP06689.1 - 6e-10 38.7 0.0 1.5e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFP06689.1 - 2.3e-09 37.0 0.0 4.3e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Flg_hook PF02120.16 KFP06689.1 - 0.085 12.7 0.3 0.22 11.4 0.3 1.7 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK FlaC_arch PF05377.11 KFP06689.1 - 0.35 11.3 5.2 0.22 11.9 0.6 3.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DASH_Dad3 PF08656.10 KFP06689.1 - 2.6 8.2 5.8 5.2 7.2 1.1 2.9 2 0 0 2 2 2 0 DASH complex subunit Dad3 TolA_bind_tri PF16331.5 KFP06689.1 - 5.4 7.2 10.9 2.2 8.4 2.6 3.3 2 0 0 2 2 2 0 TolA binding protein trimerisation UPF0020 PF01170.18 KFP06690.1 - 4.4e-46 157.1 0.0 6.6e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 THUMP PF02926.17 KFP06690.1 - 2.2e-13 50.6 0.3 8.6e-12 45.4 0.0 2.3 2 0 0 2 2 2 1 THUMP domain Methyltransf_25 PF13649.6 KFP06690.1 - 0.00056 20.6 0.0 0.0018 19.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 KFP06690.1 - 0.0015 18.0 0.0 0.0048 16.4 0.0 1.8 1 1 1 2 2 2 1 RRNA methyltransferase AviRa MTS PF05175.14 KFP06690.1 - 0.038 13.6 0.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_11 PF08241.12 KFP06690.1 - 0.096 13.3 0.0 0.31 11.7 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain NPR3 PF03666.13 KFP06690.1 - 0.58 8.9 6.6 0.79 8.4 6.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 VHL PF01847.16 KFP06691.1 - 6.5e-36 122.1 0.0 1.4e-35 121.1 0.0 1.5 2 0 0 2 2 2 1 VHL beta domain VHL_C PF17211.3 KFP06691.1 - 1.9e-30 104.7 2.3 2.7e-30 104.1 2.3 1.2 1 0 0 1 1 1 1 VHL box domain STAT2_C PF12188.8 KFP06691.1 - 0.033 14.1 0.4 0.089 12.7 0.2 1.9 2 0 0 2 2 2 0 Signal transducer and activator of transcription 2 C terminal WD40 PF00400.32 KFP06692.1 - 2.3e-22 78.9 21.2 0.0005 20.8 0.2 6.6 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP06692.1 - 4.2e-07 30.2 5.2 0.023 15.0 0.0 4.6 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L32e PF01655.18 KFP06693.1 - 1e-57 193.2 3.3 1.2e-57 192.9 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 HhH-GPD PF00730.25 KFP06694.1 - 8.6e-06 26.2 0.0 1.1e-05 25.9 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein WD40 PF00400.32 KFP06695.1 - 1.8e-15 57.0 12.4 2.9e-06 27.9 0.0 7.4 8 0 0 8 8 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP06695.1 - 4.2e-11 43.0 0.5 0.017 15.4 0.1 5.3 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KFP06695.1 - 5.2e-06 25.8 6.1 0.0042 16.2 0.2 5.0 5 1 0 5 5 5 2 Coatomer WD associated region eIF2A PF08662.11 KFP06695.1 - 0.0024 17.8 0.4 0.32 10.8 0.0 3.4 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Prok-RING_4 PF14447.6 KFP06695.1 - 0.0057 16.5 2.6 0.024 14.5 2.6 2.1 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Clathrin PF00637.20 KFP06695.1 - 0.011 15.6 2.3 0.4 10.5 0.1 3.4 1 1 3 4 4 4 0 Region in Clathrin and VPS TPR_7 PF13176.6 KFP06695.1 - 0.011 15.7 8.3 0.05 13.7 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFP06695.1 - 0.027 14.8 4.7 0.95 9.8 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Ge1_WD40 PF16529.5 KFP06695.1 - 0.048 12.6 0.6 0.71 8.8 0.0 2.6 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC3 PF12895.7 KFP06695.1 - 0.17 12.2 12.8 0.31 11.3 0.2 3.8 5 0 0 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KFP06695.1 - 0.19 11.9 19.7 0.34 11.1 0.7 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat zf-RING_4 PF14570.6 KFP06695.1 - 7.2 6.5 10.0 9.3 6.1 2.5 2.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain 7tm_1 PF00001.21 KFP06696.1 - 3.2e-44 151.2 14.3 4e-44 150.9 14.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Rhodopsin_N PF10413.9 KFP06696.1 - 1.5e-26 91.9 1.3 1.5e-26 91.9 1.3 2.1 2 0 0 2 2 2 1 Amino terminal of the G-protein receptor rhodopsin 7TM_GPCR_Srw PF10324.9 KFP06696.1 - 3.2e-08 33.2 19.4 1.3e-07 31.2 19.4 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 KFP06696.1 - 3.9e-08 33.0 20.0 5.5e-08 32.5 20.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.9 KFP06696.1 - 4.3e-08 32.8 17.3 6.6e-08 32.2 17.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP06696.1 - 1.1e-06 28.5 19.3 1.1e-06 28.5 19.3 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx TAS2R PF05296.13 KFP06696.1 - 0.0013 18.0 11.5 0.0034 16.5 2.0 2.1 2 0 0 2 2 2 2 Taste receptor protein (TAS2R) 7tm_4 PF13853.6 KFP06696.1 - 0.033 13.9 18.0 0.4 10.4 18.0 2.0 1 1 0 1 1 1 0 Olfactory receptor DUF4079 PF13301.6 KFP06696.1 - 2.5 8.3 7.0 9.3 6.4 3.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) DHHC PF01529.20 KFP06696.1 - 3.8 7.6 18.6 0.37 10.9 3.4 2.6 2 1 0 2 2 2 0 DHHC palmitoyltransferase Tmemb_cc2 PF10267.9 KFP06698.1 - 3.2e-170 566.6 14.1 3.2e-170 566.6 14.1 1.8 2 0 0 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein LMBR1 PF04791.16 KFP06698.1 - 0.00084 18.4 0.5 0.00084 18.4 0.5 2.2 2 0 0 2 2 2 1 LMBR1-like membrane protein CbiA PF01656.23 KFP06698.1 - 0.019 15.0 0.2 0.095 12.8 0.0 2.1 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain UPF0565 PF10561.9 KFP06698.1 - 0.082 12.1 5.5 0.049 12.8 0.6 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 Exonuc_VII_L PF02601.15 KFP06698.1 - 1.2 8.6 24.0 0.86 9.1 9.1 3.0 3 0 0 3 3 3 0 Exonuclease VII, large subunit TRH PF05438.12 KFP06699.1 - 6.4e-89 297.5 11.8 4.8e-86 288.1 7.6 2.0 2 0 0 2 2 2 2 Thyrotropin-releasing hormone (TRH) Chal_sti_synt_C PF02797.15 KFP06699.1 - 7.8e-05 22.7 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Med2 PF11214.8 KFP06699.1 - 0.054 13.6 0.1 0.17 12.1 0.0 1.9 2 0 0 2 2 2 0 Mediator complex subunit 2 NPF PF16601.5 KFP06700.1 - 3.5e-49 167.8 18.6 8.5e-49 166.6 18.6 1.7 1 0 0 1 1 1 1 Rabosyn-5 repeating NPF sequence-motif Rbsn PF11464.8 KFP06700.1 - 1.4e-27 95.1 16.5 1.8e-15 56.4 4.0 3.3 3 0 0 3 3 3 2 Rabenosyn Rab binding domain FYVE PF01363.21 KFP06700.1 - 3.9e-18 65.3 6.0 1.1e-17 63.8 6.0 1.9 1 0 0 1 1 1 1 FYVE zinc finger zf-Di19 PF05605.12 KFP06700.1 - 0.028 14.7 0.2 0.028 14.7 0.2 2.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.21 KFP06700.1 - 0.15 12.3 5.6 0.078 13.2 1.7 2.4 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain RNA_POL_M_15KD PF02150.16 KFP06700.1 - 0.19 11.6 5.1 0.28 11.1 0.8 2.7 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit RAMPs PF03787.15 KFP06700.1 - 0.28 11.2 1.9 1.6 8.7 1.9 2.2 1 1 0 1 1 1 0 RAMP superfamily zinc_ribbon_9 PF14369.6 KFP06700.1 - 0.37 11.1 6.8 0.19 12.0 0.3 3.0 3 0 0 3 3 3 0 zinc-ribbon zinc_ribbon_12 PF11331.8 KFP06700.1 - 0.44 10.4 3.2 0.32 10.8 0.2 2.4 2 0 0 2 2 2 0 Probable zinc-ribbon domain C1_1 PF00130.22 KFP06700.1 - 1.9 8.4 9.9 0.65 9.9 3.5 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 KFP06700.1 - 2.4 8.3 11.2 0.29 11.2 2.5 2.9 3 0 0 3 3 3 0 Double zinc ribbon L51_S25_CI-B8 PF05047.16 KFP06701.1 - 2.8e-13 49.6 1.0 6.5e-13 48.4 0.3 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Hormone_recep PF00104.30 KFP06702.1 - 1.5e-45 155.4 0.7 2.7e-45 154.5 0.7 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFP06702.1 - 5.8e-32 110.0 16.3 1.2e-31 109.0 16.3 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) FAA_hydro_N_2 PF18288.1 KFP06702.1 - 0.046 14.1 1.0 0.62 10.5 0.1 3.1 2 2 0 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 Glyco_hydro_99 PF16317.5 KFP06703.1 - 4.1e-171 568.7 9.9 5e-171 568.4 9.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 99 Glyco_hydro_71 PF03659.14 KFP06703.1 - 0.00066 18.6 2.9 0.00093 18.1 2.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.6 KFP06703.1 - 0.049 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) zf-C2H2 PF00096.26 KFP06705.1 - 1e-16 60.3 20.9 6e-06 26.4 2.4 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP06705.1 - 8.8e-12 44.9 7.5 1.8e-07 31.3 1.1 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP06705.1 - 7.5e-09 35.7 20.3 0.0017 19.0 2.0 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFP06705.1 - 0.00064 20.3 4.6 0.11 13.2 0.1 2.7 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-met PF12874.7 KFP06705.1 - 0.0042 17.4 5.7 0.06 13.8 0.6 2.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFP06705.1 - 0.026 14.5 1.4 0.026 14.5 1.4 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KFP06705.1 - 0.042 14.0 5.0 1.2 9.2 0.1 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2HC_2 PF13913.6 KFP06705.1 - 0.14 12.1 0.5 0.38 10.7 0.2 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type IBR PF01485.21 KFP06705.1 - 0.78 10.0 7.0 3.7 7.8 7.0 2.0 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C2H2_jaz PF12171.8 KFP06705.1 - 2.9 8.3 7.8 2.5 8.5 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 KFP06705.1 - 9.8 5.9 6.7 2.3 7.9 0.7 2.9 2 1 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 KFP06706.1 - 3.8e-16 58.6 23.1 5.3e-06 26.6 2.9 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP06706.1 - 5.5e-11 42.4 9.5 1.3e-07 31.7 1.4 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP06706.1 - 1.1e-06 28.9 20.2 0.05 14.5 1.9 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFP06706.1 - 0.069 13.6 2.9 7.7 7.1 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP06706.1 - 0.076 13.3 3.5 6.1 7.2 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 KFP06706.1 - 0.079 13.1 2.3 5.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger FOXP-CC PF16159.5 KFP06706.1 - 0.67 10.6 5.2 5.4 7.7 1.0 2.7 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KFP06706.1 - 1.2 9.2 9.4 0.99 9.5 0.9 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KFP06706.1 - 5.5 6.7 5.4 2.7 7.7 0.3 2.7 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain COMM_domain PF07258.14 KFP06707.1 - 1.4e-15 57.1 0.0 2.2e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 COMM domain DUF2829 PF11195.8 KFP06707.1 - 0.087 13.1 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2829) Peptidase_C12 PF01088.21 KFP06708.1 - 6.9e-60 202.4 0.0 7.8e-60 202.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF4757 PF15949.5 KFP06709.1 - 7.2e-45 153.5 29.4 9.3e-35 120.6 22.8 7.3 6 2 1 7 7 7 2 Domain of unknown function (DUF4757) CH PF00307.31 KFP06709.1 - 9e-12 45.1 0.1 1.1e-10 41.6 0.0 2.6 2 0 0 2 2 2 1 Calponin homology (CH) domain PDZ PF00595.24 KFP06709.1 - 7.1e-07 29.5 0.0 1.7e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain LIM PF00412.22 KFP06709.1 - 8.6e-07 29.1 7.8 2.2e-06 27.8 7.8 1.8 1 0 0 1 1 1 1 LIM domain PDZ_6 PF17820.1 KFP06709.1 - 1.7e-06 27.8 0.0 3.4e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP06709.1 - 4e-05 23.8 0.0 0.00011 22.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain RESP18 PF14948.6 KFP06709.1 - 1.1 9.6 7.2 1.6 9.1 0.3 3.1 3 0 0 3 3 3 0 RESP18 domain DNA_pol_B_palm PF14792.6 KFP06710.1 - 2.2e-38 131.0 0.0 4.7e-38 129.9 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 KFP06710.1 - 6.3e-22 77.2 0.0 1.4e-20 72.9 0.0 2.5 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 KFP06710.1 - 1.7e-17 63.3 0.0 3.7e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 KFP06710.1 - 1.2e-11 44.8 0.7 9.8e-10 38.7 0.3 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.6 KFP06710.1 - 1.6e-09 38.2 0.2 3e-06 27.7 0.0 2.8 3 0 0 3 3 2 2 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 KFP06710.1 - 0.0006 20.1 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH_2 PF12826.7 KFP06710.1 - 0.0018 18.3 0.0 0.53 10.4 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif Cdd1 PF11731.8 KFP06710.1 - 0.0035 17.5 0.0 0.028 14.7 0.0 2.4 2 1 0 2 2 2 1 Pathogenicity locus HHH_3 PF12836.7 KFP06710.1 - 0.0053 17.0 0.3 2.4 8.5 0.0 3.6 4 1 0 4 4 4 1 Helix-hairpin-helix motif HHH PF00633.23 KFP06710.1 - 0.0074 16.1 0.1 5 7.2 0.2 2.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif WSN PF02206.18 KFP06710.1 - 0.011 15.6 0.1 5.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF3701 PF12482.8 KFP06710.1 - 0.16 12.1 0.0 16 5.7 0.0 2.4 2 0 0 2 2 2 0 Phage integrase protein Porin_3 PF01459.22 KFP06711.1 - 5.5e-86 288.4 7.7 6.2e-86 288.2 7.7 1.0 1 0 0 1 1 1 1 Eukaryotic porin IKBKB_SDD PF18397.1 KFP06712.1 - 1e-132 441.6 16.0 1.8e-132 440.8 16.0 1.4 1 0 0 1 1 1 1 IQBAL scaffold dimerization domain Pkinase PF00069.25 KFP06712.1 - 2.7e-40 138.4 0.0 6.3e-40 137.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP06712.1 - 6.4e-27 94.5 0.0 1.6e-26 93.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase IKKbetaNEMObind PF12179.8 KFP06712.1 - 4e-15 55.5 7.8 4e-15 55.5 7.8 2.8 2 0 0 2 2 2 1 I-kappa-kinase-beta NEMO binding domain Pkinase_fungal PF17667.1 KFP06712.1 - 2.2e-07 30.0 0.0 4.8e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase ubiquitin PF00240.23 KFP06712.1 - 0.00011 21.9 0.1 0.00037 20.2 0.1 2.0 1 0 0 1 1 1 1 Ubiquitin family Kdo PF06293.14 KFP06712.1 - 0.00011 21.7 0.0 0.00021 20.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP06712.1 - 0.002 18.1 0.2 0.01 15.8 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KFP06712.1 - 0.014 15.0 0.4 0.04 13.4 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL TBK1_ULD PF18396.1 KFP06712.1 - 0.019 14.9 0.1 0.057 13.3 0.1 1.8 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain NPV_P10 PF05531.12 KFP06712.1 - 0.8 10.2 5.0 10 6.7 0.9 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Trypsin PF00089.26 KFP06713.1 - 3.9e-68 229.6 0.0 5.8e-68 229.0 0.0 1.3 1 0 0 1 1 1 1 Trypsin Kringle PF00051.18 KFP06713.1 - 3.7e-45 152.1 28.5 5.5e-24 84.3 5.3 3.1 4 0 0 4 4 4 2 Kringle domain fn1 PF00039.18 KFP06713.1 - 1.4e-05 25.2 3.5 1.4e-05 25.2 3.5 2.6 2 0 0 2 2 2 1 Fibronectin type I domain Trypsin_2 PF13365.6 KFP06713.1 - 3.3e-05 24.8 0.0 6.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 KFP06713.1 - 0.0078 15.8 0.1 3.8 7.0 0.0 2.3 2 0 0 2 2 2 2 Chymotrypsin family Peptidase-S1 DUF1986 PF09342.11 KFP06713.1 - 0.013 15.9 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) EGF PF00008.27 KFP06713.1 - 0.016 15.5 4.7 0.016 15.5 4.7 4.2 5 0 0 5 5 5 0 EGF-like domain hEGF PF12661.7 KFP06713.1 - 0.43 11.3 9.0 1.3 9.8 4.4 4.0 2 0 0 2 2 2 0 Human growth factor-like EGF Adap_comp_sub PF00928.21 KFP06714.1 - 7.4e-76 255.0 0.0 8.8e-76 254.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFP06714.1 - 4.1e-05 23.5 0.8 7.5e-05 22.7 0.8 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain UPA_2 PF17809.1 KFP06715.1 - 1.9e-07 31.0 0.1 2.5e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 UPA domain Acyltransferase PF01553.21 KFP06716.1 - 4e-19 68.6 0.1 8.5e-19 67.5 0.1 1.6 1 0 0 1 1 1 1 Acyltransferase Topo_C_assoc PF14370.6 KFP06716.1 - 0.12 12.3 0.1 0.47 10.4 0.0 2.0 2 0 0 2 2 2 0 C-terminal topoisomerase domain Sld5 PF05916.11 KFP06717.1 - 6.7e-06 26.5 0.3 1.2e-05 25.7 0.2 1.6 1 1 1 2 2 2 1 GINS complex protein SLD5_C PF16922.5 KFP06717.1 - 0.00015 21.9 0.0 0.00027 21.1 0.0 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus HipN PF18253.1 KFP06717.1 - 0.0045 16.6 1.8 0.044 13.5 0.0 3.1 4 0 0 4 4 4 1 Hsp70-interacting protein N N-terminal domain Erf4 PF10256.9 KFP06718.1 - 5.3e-22 78.1 0.0 5.9e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family TC1 PF15063.6 KFP06719.1 - 6.1e-36 122.1 0.1 7.6e-36 121.8 0.1 1.1 1 0 0 1 1 1 1 Thyroid cancer protein 1 tRNA_bind_2 PF13725.6 KFP06719.1 - 0.0099 15.6 0.7 0.011 15.4 0.7 1.1 1 0 0 1 1 1 1 Possible tRNA binding domain MRP-S22 PF10245.9 KFP06719.1 - 0.032 14.0 1.2 0.037 13.8 1.2 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S22 Reprolysin PF01421.19 KFP06720.1 - 2.6e-67 226.6 0.1 4.6e-67 225.8 0.1 1.4 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.12 KFP06720.1 - 5.2e-36 123.6 6.7 5.2e-36 123.6 6.7 3.6 4 1 0 4 4 1 1 ADAM cysteine-rich Pep_M12B_propep PF01562.19 KFP06720.1 - 3.1e-32 111.7 0.1 3.1e-32 111.7 0.1 1.8 2 0 0 2 2 2 1 Reprolysin family propeptide Reprolysin_5 PF13688.6 KFP06720.1 - 2.2e-21 76.9 0.2 6.5e-21 75.4 0.2 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12 Disintegrin PF00200.23 KFP06720.1 - 4.1e-20 72.4 29.1 4.1e-20 72.4 29.1 4.9 4 1 0 4 4 3 1 Disintegrin Reprolysin_3 PF13582.6 KFP06720.1 - 5.1e-15 56.1 0.1 1e-14 55.1 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP06720.1 - 9.2e-12 45.0 0.1 1.4e-11 44.4 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFP06720.1 - 2.5e-09 37.3 0.5 4.6e-09 36.5 0.5 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.13 KFP06720.1 - 0.0012 19.2 10.9 0.0012 19.2 10.9 6.3 5 2 1 6 6 3 1 EGF-like domain Peptidase_M57 PF12388.8 KFP06720.1 - 0.008 15.8 1.7 0.015 14.9 1.7 1.3 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.24 KFP06720.1 - 0.027 14.3 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Matrixin ADAM_CR_2 PF17771.1 KFP06720.1 - 0.064 13.8 0.4 0.064 13.8 0.4 6.3 5 1 1 6 6 3 0 ADAM cysteine-rich domain Peptidase_M66 PF10462.9 KFP06720.1 - 0.098 11.6 0.3 0.19 10.7 0.3 1.4 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M43 PF05572.13 KFP06720.1 - 1.8 8.5 6.6 0.14 12.1 0.2 2.3 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A PH PF00169.29 KFP06721.1 - 6.8e-19 68.3 0.8 9.7e-11 42.1 0.0 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KFP06721.1 - 6.9e-08 32.9 0.5 0.0012 19.3 0.6 2.4 2 1 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 KFP06721.1 - 1.4e-07 31.7 2.6 0.00037 20.7 0.1 2.9 2 1 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.7 KFP06721.1 - 2.3e-05 24.5 0.0 3.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.6 KFP06721.1 - 0.0012 19.2 0.0 0.0065 16.8 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_17 PF18012.1 KFP06721.1 - 0.17 11.7 0.1 0.4 10.4 0.1 1.7 1 1 0 1 1 1 0 PH domain Pkinase_Tyr PF07714.17 KFP06722.1 - 4.4e-105 350.6 0.0 6.6e-105 350.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP06722.1 - 1.4e-45 155.7 0.0 2.3e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.16 KFP06722.1 - 1.6e-37 127.4 0.0 6.3e-14 51.8 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP06722.1 - 6.7e-32 109.9 0.2 4.1e-12 46.5 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFP06722.1 - 3.4e-31 107.2 0.1 5.4e-09 36.1 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFP06722.1 - 1.2e-24 86.5 0.3 3.5e-10 40.1 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFP06722.1 - 1.5e-14 54.1 2.7 2.8e-05 24.2 0.0 5.4 3 3 0 3 3 3 3 Immunoglobulin V-set domain FGFR3_TM PF18123.1 KFP06722.1 - 2.1e-14 52.7 4.0 3.5e-14 52.0 4.0 1.4 1 0 0 1 1 1 1 Fibroblast growth factor receptor 3 transmembrane domain Ig_5 PF16681.5 KFP06722.1 - 5.3e-09 36.4 0.1 0.018 15.4 0.0 4.1 3 1 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFP06722.1 - 1.7e-06 28.2 0.0 0.0019 18.4 0.0 3.7 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFP06722.1 - 1.1e-05 24.9 0.0 0.2 11.3 0.0 3.4 3 0 0 3 3 3 1 Immunoglobulin domain C2-set_2 PF08205.12 KFP06722.1 - 0.00055 20.0 0.0 0.45 10.6 0.0 3.3 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFP06722.1 - 0.02 14.9 0.0 21 5.3 0.0 3.5 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain DUF2890 PF11081.8 KFP06722.1 - 0.035 14.2 0.4 0.069 13.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) V-set_CD47 PF08204.11 KFP06722.1 - 0.076 13.0 0.1 0.98 9.4 0.0 2.7 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain DUF4396 PF14342.6 KFP06722.1 - 0.081 13.3 0.5 0.13 12.6 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) Pkinase_fungal PF17667.1 KFP06722.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF1615 PF07759.12 KFP06722.1 - 0.18 11.0 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1615) LETM1 PF07766.13 KFP06723.1 - 2.9e-99 331.8 8.8 3.4e-99 331.6 8.8 1.0 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.27 KFP06723.1 - 0.011 15.4 0.1 0.054 13.3 0.1 2.2 1 1 0 1 1 1 0 SAP domain OATP PF03137.20 KFP06723.1 - 0.37 9.0 0.3 0.55 8.5 0.3 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family C5HCH PF17982.1 KFP06724.1 - 7.1e-24 83.7 12.4 7.1e-24 83.7 12.4 5.0 4 1 0 4 4 4 1 NSD Cys-His rich domain SET PF00856.28 KFP06724.1 - 4.2e-21 76.1 0.7 4.5e-20 72.7 0.4 2.8 3 1 0 3 3 3 1 SET domain AWS PF17907.1 KFP06724.1 - 3.3e-17 62.2 8.5 3.3e-17 62.2 8.5 5.1 5 0 0 5 5 5 1 AWS domain PWWP PF00855.17 KFP06724.1 - 1.1e-13 51.4 0.5 1.1e-13 51.4 0.5 2.8 2 1 0 2 2 2 1 PWWP domain PHD PF00628.29 KFP06724.1 - 2.2e-11 43.5 73.1 5.1e-05 23.1 12.9 6.7 4 2 2 6 6 6 4 PHD-finger zf-HC5HC2H_2 PF13832.6 KFP06724.1 - 0.004 17.3 8.3 0.004 17.3 8.3 6.3 3 2 3 6 6 6 2 PHD-zinc-finger like domain PAP2 PF01569.21 KFP06725.1 - 7.1e-30 103.5 0.8 7.1e-30 103.5 0.8 1.6 2 0 0 2 2 2 1 PAP2 superfamily YhhN PF07947.14 KFP06725.1 - 0.061 12.9 7.3 1.6 8.3 7.5 2.6 1 1 0 1 1 1 0 YhhN family PAP2_C PF14360.6 KFP06725.1 - 0.073 13.6 0.1 0.15 12.6 0.1 1.5 1 0 0 1 1 1 0 PAP2 superfamily C-terminal PAP2_3 PF14378.6 KFP06725.1 - 0.17 11.6 4.2 1.9 8.2 4.3 2.3 1 1 0 1 1 1 0 PAP2 superfamily DUF4231 PF14015.6 KFP06725.1 - 0.22 12.0 0.0 0.41 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DDHD PF02862.17 KFP06726.1 - 6.7e-53 180.1 0.0 1e-52 179.6 0.0 1.3 1 0 0 1 1 1 1 DDHD domain SAM_1 PF00536.30 KFP06726.1 - 1.9e-14 53.8 0.0 3.3e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) WWE PF02825.20 KFP06726.1 - 1.4e-13 51.2 3.6 2.6e-07 31.1 0.1 3.2 2 1 1 3 3 3 2 WWE domain SAM_2 PF07647.17 KFP06726.1 - 3e-06 27.2 0.0 6.6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) LSM PF01423.22 KFP06727.1 - 0.00043 19.9 0.1 0.00092 18.9 0.1 1.6 1 0 0 1 1 1 1 LSM domain Pkinase PF00069.25 KFP06728.1 - 2.9e-51 174.4 0.0 3.9e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP06728.1 - 1.5e-27 96.5 0.0 2.3e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP06728.1 - 1.3e-05 24.7 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP06728.1 - 3.6e-05 22.7 0.0 5.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RGS PF00615.19 KFP06728.1 - 0.0086 16.3 0.2 0.03 14.6 0.0 1.8 2 0 0 2 2 2 1 Regulator of G protein signaling domain APH PF01636.23 KFP06728.1 - 0.075 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KFP06728.1 - 0.11 12.1 0.2 1.2 8.7 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 START PF01852.19 KFP06729.1 - 4.3e-46 157.0 0.0 5.3e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 START domain Polyketide_cyc PF03364.20 KFP06729.1 - 0.0092 16.2 0.0 0.03 14.5 0.0 1.9 2 1 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport TB2_DP1_HVA22 PF03134.19 KFP06730.1 - 3.1e-21 75.1 10.9 4.3e-21 74.6 10.9 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family PH PF00169.29 KFP06731.1 - 4.2e-06 27.2 0.0 4.6e-06 27.1 0.0 1.0 1 0 0 1 1 1 1 PH domain Polysacc_synt_4 PF04669.13 KFP06732.1 - 0.0004 20.0 0.0 0.00041 20.0 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis IBN_N PF03810.19 KFP06733.1 - 3e-13 49.5 0.1 3e-13 49.5 0.1 3.3 4 0 0 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KFP06733.1 - 0.0065 16.5 0.6 0.0065 16.5 0.6 3.7 4 0 0 4 4 4 1 Exportin 1-like protein Rep_fac_C PF08542.11 KFP06733.1 - 3.1 8.3 4.6 15 6.1 0.1 4.1 5 0 0 5 5 5 0 Replication factor C C-terminal domain GDNF PF02351.16 KFP06734.1 - 2.2e-46 156.7 44.8 1.6e-24 86.7 5.5 3.1 3 0 0 3 3 3 3 GDNF/GAS1 domain Apo-CIII PF05778.12 KFP06734.1 - 0.18 11.5 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) ATP-synt_ab PF00006.25 KFP06735.1 - 2.7e-68 229.8 0.0 3.9e-68 229.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KFP06735.1 - 4.3e-13 49.6 0.4 1e-12 48.4 0.1 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain Glyco_hydro_31 PF01055.26 KFP06736.1 - 2.1e-143 478.7 5.8 2.8e-143 478.3 5.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KFP06736.1 - 1.5e-37 128.3 0.1 2e-34 118.2 0.0 2.6 2 0 0 2 2 2 2 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 KFP06736.1 - 3.4e-20 71.7 17.6 9.6e-12 44.6 6.1 2.8 3 0 0 3 3 3 2 Trefoil (P-type) domain Gal_mutarotas_2 PF13802.6 KFP06736.1 - 0.00083 19.6 0.3 0.002 18.4 0.3 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 KFP06736.1 - 0.0065 16.7 0.5 0.02 15.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) TEX29 PF15839.5 KFP06736.1 - 0.98 10.1 2.8 17 6.1 0.1 2.6 2 0 0 2 2 2 0 Testis-expressed sequence 29 protein dUTPase PF00692.19 KFP06738.1 - 1.4e-14 53.8 0.0 1.9e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 dUTPase RVP PF00077.20 KFP06738.1 - 0.0036 17.6 0.1 0.0098 16.2 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease RVT_1 PF00078.27 KFP06739.1 - 1.6e-27 96.5 0.0 2.1e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 KFP06739.1 - 1.1e-08 34.8 0.3 1.8e-08 34.1 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase thumb domain T2SSppdC PF12528.8 KFP06739.1 - 2.2 9.1 4.8 18 6.2 1.7 2.7 3 0 0 3 3 3 0 Type II secretion prepilin peptidase dependent protein C rve PF00665.26 KFP06740.1 - 4.2e-28 97.9 0.1 1.2e-27 96.5 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Integrase_Zn PF02022.19 KFP06740.1 - 5.2e-15 55.1 0.9 1.1e-14 54.1 0.9 1.6 1 0 0 1 1 1 1 Integrase Zinc binding domain RNase_H PF00075.24 KFP06740.1 - 4.9e-07 30.0 0.0 1.2e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 RNase H DDE_Tnp_IS240 PF13610.6 KFP06740.1 - 6.6e-05 23.2 0.0 0.00029 21.1 0.0 2.0 2 0 0 2 2 2 1 DDE domain Baculo_LEF5_C PF11792.8 KFP06740.1 - 0.03 14.0 0.1 0.059 13.0 0.1 1.5 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain rve_3 PF13683.6 KFP06740.1 - 0.14 12.0 0.0 0.61 9.9 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain KH_1 PF00013.29 KFP06741.1 - 3.5e-44 148.5 13.1 4.4e-20 71.3 1.9 3.3 3 0 0 3 3 3 3 KH domain ROKNT PF08067.11 KFP06741.1 - 4.7e-23 81.2 11.6 8.4e-23 80.4 11.6 1.5 1 0 0 1 1 1 1 ROKNT (NUC014) domain KH_2 PF07650.17 KFP06741.1 - 7.4e-16 57.7 1.0 0.00062 19.5 0.5 3.5 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KFP06741.1 - 2.2e-08 33.9 7.8 3.6e-06 26.8 0.2 3.5 3 1 0 3 3 3 2 KH domain KH_5 PF13184.6 KFP06741.1 - 1.1e-05 25.5 2.6 0.24 11.5 0.1 3.5 3 0 0 3 3 3 2 NusA-like KH domain DJ-1_PfpI PF01965.24 KFP06741.1 - 0.044 13.6 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family MOEP19 PF16005.5 KFP06741.1 - 0.048 13.7 0.0 2.7 8.0 0.0 2.3 2 0 0 2 2 2 0 KH-like RNA-binding domain C1q PF00386.21 KFP06742.1 - 4.1e-16 59.4 0.2 7.7e-16 58.5 0.2 1.5 1 0 0 1 1 1 1 C1q domain EMI PF07546.13 KFP06742.1 - 3.1e-14 53.5 3.8 7e-14 52.3 3.8 1.6 1 0 0 1 1 1 1 EMI domain Phlebovirus_NSM PF07246.11 KFP06742.1 - 0.009 15.4 0.7 0.009 15.4 0.7 3.0 3 1 1 4 4 4 1 Phlebovirus nonstructural protein NS-M Synuclein PF01387.17 KFP06743.1 - 2.9e-51 173.2 24.8 3.2e-51 173.1 24.8 1.0 1 0 0 1 1 1 1 Synuclein YtxH PF12732.7 KFP06743.1 - 0.2 12.2 8.0 0.33 11.5 1.3 2.0 1 1 1 2 2 2 0 YtxH-like protein Augurin PF15187.6 KFP06744.1 - 2.6e-21 75.9 4.2 2.7e-21 75.9 4.2 1.0 1 0 0 1 1 1 1 Oesophageal cancer-related gene 4 ELFV_dehydrog PF00208.21 KFP06745.1 - 1.8e-55 188.3 0.0 2.7e-52 177.9 0.0 2.1 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KFP06745.1 - 3.7e-42 143.3 0.0 7.5e-42 142.3 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 KFP06745.1 - 0.055 12.8 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAM35_C PF15793.5 KFP06746.1 - 4.7e-77 257.3 0.7 8.3e-77 256.5 0.7 1.4 1 0 0 1 1 1 1 Protein family FAM35, C-terminal EMC3_TMCO1 PF01956.16 KFP06746.1 - 5 6.8 6.1 0.86 9.3 1.3 2.2 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like GRIN_C PF15235.6 KFP06747.1 - 5.3e-36 123.8 0.1 1.4e-35 122.4 0.1 1.7 1 0 0 1 1 1 1 G protein-regulated inducer of neurite outgrowth C-terminus ARA70 PF12489.8 KFP06748.1 - 1.7e-64 216.0 37.6 2.4e-38 131.3 8.0 5.7 2 1 4 6 6 6 3 Nuclear coactivator Cas_DxTHG PF09455.10 KFP06748.1 - 0.59 9.7 4.9 0.19 11.2 1.7 1.8 2 0 0 2 2 2 0 CRISPR-associated (Cas) DxTHG family BRK PF07533.16 KFP06748.1 - 0.7 9.6 11.6 0.61 9.8 0.2 3.8 4 0 0 4 4 4 0 BRK domain MRP-63 PF14978.6 KFP06748.1 - 2.9 8.6 5.8 4.9 7.8 0.4 3.1 3 0 0 3 3 3 0 Mitochondrial ribosome protein 63 Tim17 PF02466.19 KFP06749.1 - 7.6e-20 71.4 2.4 8.5e-20 71.2 2.4 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PARG_cat PF05028.14 KFP06750.1 - 3.9e-136 453.8 0.0 5.6e-136 453.3 0.0 1.2 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) AKAP_110 PF05716.13 KFP06750.1 - 0.006 14.9 0.0 0.011 14.1 0.0 1.3 1 0 0 1 1 1 1 A-kinase anchor protein 110 kDa (AKAP 110) E1_dh PF00676.20 KFP06751.1 - 4.5e-88 295.1 0.1 8.1e-88 294.2 0.1 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 KFP06751.1 - 1.7e-67 226.5 0.0 2.6e-67 225.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 KFP06751.1 - 9.8e-55 184.4 0.0 1.8e-54 183.6 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KFP06751.1 - 7.1e-19 67.1 4.2 1.6e-18 66.0 2.0 2.3 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus GGA_N-GAT PF18308.1 KFP06751.1 - 0.016 14.8 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 GGA N-GAT domain Carn_acyltransf PF00755.20 KFP06752.1 - 5.2e-196 652.8 0.0 5.8e-196 652.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase MFS_1 PF07690.16 KFP06753.1 - 2.3e-28 99.1 34.0 3.4e-25 88.7 27.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP06753.1 - 2.9e-05 23.1 1.2 2.9e-05 23.1 1.2 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter BT1 PF03092.16 KFP06753.1 - 0.012 13.9 0.2 0.021 13.1 0.2 1.4 1 0 0 1 1 1 0 BT1 family LacY_symp PF01306.19 KFP06753.1 - 0.19 10.5 4.8 0.15 10.8 1.0 2.2 2 1 0 2 2 2 0 LacY proton/sugar symporter 7tm_1 PF00001.21 KFP06754.1 - 1.6e-25 90.0 12.7 7.9e-24 84.4 12.7 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP06754.1 - 8.9e-06 25.5 9.7 1.5e-05 24.8 9.7 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFP06754.1 - 0.054 12.9 6.5 0.11 11.9 6.5 1.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx E1_dh PF00676.20 KFP06754.1 - 0.23 10.4 0.0 0.34 9.8 0.0 1.1 1 0 0 1 1 1 0 Dehydrogenase E1 component LRR_8 PF13855.6 KFP06755.1 - 1.1e-22 79.6 2.8 1.6e-12 47.0 3.2 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFP06755.1 - 1.8e-11 44.1 17.3 1.2e-06 28.7 1.9 3.1 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP06755.1 - 4.2e-07 29.6 3.0 2.4 9.0 0.0 5.0 5 0 0 5 5 5 2 Leucine Rich Repeat I-set PF07679.16 KFP06755.1 - 0.0039 17.2 0.0 0.006 16.6 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP06755.1 - 0.018 15.6 0.0 0.03 14.9 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain LRR_9 PF14580.6 KFP06755.1 - 0.15 11.5 0.4 1.4 8.4 0.2 1.8 1 1 1 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 KFP06755.1 - 0.99 9.6 7.1 0.81 9.9 0.2 3.2 3 0 0 3 3 3 0 Leucine Rich repeat Cadherin PF00028.17 KFP06756.1 - 1.1e-70 234.1 5.9 4e-16 59.2 0.1 6.4 6 0 0 6 6 6 6 Cadherin domain Big_9 PF17963.1 KFP06756.1 - 0.016 15.9 18.8 0.094 13.5 1.6 5.4 6 0 0 6 6 6 0 Bacterial Ig domain He_PIG PF05345.12 KFP06756.1 - 0.017 15.3 2.6 3.1 8.0 0.0 4.4 5 0 0 5 5 5 0 Putative Ig domain Cadherin_2 PF08266.12 KFP06756.1 - 0.1 12.4 0.1 1.7 8.5 0.0 2.9 3 0 0 3 3 3 0 Cadherin-like Fn3_assoc PF13287.6 KFP06756.1 - 0.5 10.5 3.2 24 5.1 0.2 3.5 3 0 0 3 3 3 0 Fn3 associated IQ PF00612.27 KFP06758.1 - 1.7e-06 27.3 1.5 1.7e-06 27.3 1.5 3.0 3 0 0 3 3 3 1 IQ calmodulin-binding motif OmpH PF03938.14 KFP06758.1 - 5.5 7.3 12.8 1 9.7 5.9 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Oxysterol_BP PF01237.18 KFP06759.1 - 8.3e-14 51.2 0.3 1.5e-13 50.3 0.3 1.5 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 KFP06759.1 - 3.1e-05 24.2 0.0 0.00011 22.4 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFP06759.1 - 3.6e-05 24.2 0.0 0.00011 22.7 0.0 1.8 2 0 0 2 2 2 1 PH domain Syntaxin-6_N PF09177.11 KFP06759.1 - 0.00081 19.9 5.1 0.064 13.8 0.6 3.5 2 1 1 3 3 3 1 Syntaxin 6, N-terminal CENP-Q PF13094.6 KFP06759.1 - 0.0046 17.2 5.7 0.66 10.2 0.7 2.3 2 0 0 2 2 2 2 CENP-Q, a CENPA-CAD centromere complex subunit PH_11 PF15413.6 KFP06759.1 - 0.0084 16.5 0.0 0.028 14.8 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 KFP06759.1 - 0.013 15.8 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain PH_13 PF16652.5 KFP06759.1 - 0.02 14.7 0.5 0.051 13.4 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain Spc7 PF08317.11 KFP06759.1 - 0.043 12.7 5.1 0.068 12.0 5.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein betaPIX_CC PF16523.5 KFP06759.1 - 0.058 13.2 0.5 0.13 12.1 0.5 1.5 1 0 0 1 1 1 0 betaPIX coiled coil Flu_B_NS1 PF02942.14 KFP06759.1 - 0.1 11.7 0.2 0.18 10.9 0.2 1.3 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) MbeD_MobD PF04899.12 KFP06759.1 - 0.13 12.4 2.1 0.53 10.4 0.4 2.3 2 0 0 2 2 2 0 MbeD/MobD like CENP-F_leu_zip PF10473.9 KFP06759.1 - 0.22 11.6 6.5 0.16 12.0 1.9 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MerR-DNA-bind PF09278.11 KFP06759.1 - 0.61 10.7 6.8 1.1 9.8 4.1 2.4 2 0 0 2 2 2 0 MerR, DNA binding Oxysterol_BP PF01237.18 KFP06760.1 - 5.1e-31 107.8 0.2 5.7e-31 107.7 0.2 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein RVT_1 PF00078.27 KFP06761.1 - 0.061 12.8 0.0 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pro_dh PF01619.18 KFP06762.1 - 5.6e-65 219.8 0.1 2.6e-63 214.3 0.1 2.0 1 1 0 1 1 1 1 Proline dehydrogenase HrpB2 PF09487.10 KFP06762.1 - 0.053 13.9 0.3 0.14 12.5 0.1 1.8 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) DUF4693 PF15764.5 KFP06762.1 - 0.058 13.0 1.7 4.2 6.9 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4693) Laminin_EGF PF00053.24 KFP06763.1 - 5.9e-23 80.8 175.4 0.0038 17.3 13.6 11.0 2 1 8 10 10 10 9 Laminin EGF domain EGF_2 PF07974.13 KFP06763.1 - 0.003 17.9 31.0 0.0067 16.8 12.1 16.6 12 3 4 16 16 16 8 EGF-like domain DSL PF01414.19 KFP06763.1 - 0.0052 17.0 14.1 0.0052 17.0 14.1 10.1 6 1 2 9 9 9 5 Delta serrate ligand Tweety PF04906.13 KFP06763.1 - 0.042 12.5 3.1 0.07 11.8 3.1 1.2 1 0 0 1 1 1 0 Tweety DGCR6 PF07324.11 KFP06764.1 - 1.1e-51 175.3 6.3 1.2e-51 175.1 6.3 1.0 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein AA_permease_2 PF13520.6 KFP06765.1 - 2.4e-46 158.5 41.2 2.4e-46 158.5 41.2 2.0 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 KFP06765.1 - 6e-37 127.4 41.0 1.2e-36 126.4 32.0 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease_C PF13906.6 KFP06765.1 - 9.6e-21 73.6 8.6 9.6e-21 73.6 8.6 4.1 4 1 0 4 4 4 1 C-terminus of AA_permease P2X_receptor PF00864.19 KFP06766.1 - 2e-121 405.6 0.1 2.2e-121 405.4 0.1 1.0 1 0 0 1 1 1 1 ATP P2X receptor WAP PF00095.21 KFP06766.1 - 0.0077 16.6 3.0 0.017 15.5 1.6 2.3 2 0 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Transmemb_17 PF09799.9 KFP06767.1 - 6.3e-19 68.6 4.7 7e-19 68.4 4.7 1.0 1 0 0 1 1 1 1 Predicted membrane protein RSN1_7TM PF02714.15 KFP06767.1 - 0.032 13.6 3.1 0.033 13.5 3.1 1.0 1 0 0 1 1 1 0 Calcium-dependent channel, 7TM region, putative phosphate Pyr_redox_2 PF07992.14 KFP06768.1 - 1.3e-62 211.7 0.4 1.8e-62 211.2 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFP06768.1 - 7e-20 71.4 1.7 1.5e-15 57.5 0.5 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KFP06768.1 - 7.5e-18 64.3 0.1 1.8e-17 63.0 0.1 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.6 KFP06768.1 - 1.3e-17 64.1 4.5 7.9e-14 51.6 0.8 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 KFP06768.1 - 9e-09 35.8 0.0 2.2e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal HI0933_like PF03486.14 KFP06768.1 - 1.9e-08 33.5 3.6 0.0039 16.0 0.1 4.0 3 1 1 4 4 4 2 HI0933-like protein NAD_binding_8 PF13450.6 KFP06768.1 - 1.1e-07 32.0 0.4 0.00026 21.2 0.1 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Rieske_2 PF13806.6 KFP06768.1 - 2.5e-07 30.5 0.0 2.8e-06 27.2 0.0 2.5 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain DAO PF01266.24 KFP06768.1 - 7.2e-07 29.1 0.4 0.07 12.7 0.0 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KFP06768.1 - 1.1e-05 24.8 0.3 0.0015 17.8 0.0 2.9 3 0 0 3 3 3 1 FAD binding domain FAD_binding_2 PF00890.24 KFP06768.1 - 1.4e-05 24.3 4.0 0.0015 17.7 0.1 3.7 3 1 1 4 4 4 1 FAD binding domain GIDA PF01134.22 KFP06768.1 - 4.7e-05 22.7 1.1 0.77 8.8 0.0 3.9 3 1 1 4 4 4 2 Glucose inhibited division protein A Thi4 PF01946.17 KFP06768.1 - 0.00059 19.2 0.1 0.18 11.0 0.0 2.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KFP06768.1 - 0.00068 19.6 0.8 0.64 10.0 0.1 3.3 3 1 1 4 4 4 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KFP06768.1 - 0.0014 18.7 0.1 0.27 11.3 0.0 2.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 KFP06768.1 - 0.0036 16.4 2.7 1.3 7.9 0.0 3.1 2 1 1 3 3 3 2 Lycopene cyclase protein DUF1188 PF06690.11 KFP06768.1 - 0.0076 15.8 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1188) TrkA_N PF02254.18 KFP06768.1 - 0.0097 16.2 0.9 2.1 8.7 0.0 2.9 3 0 0 3 3 2 1 TrkA-N domain ThiF PF00899.21 KFP06768.1 - 0.014 14.8 1.5 0.56 9.5 0.0 2.5 3 0 0 3 3 2 0 ThiF family K_oxygenase PF13434.6 KFP06768.1 - 0.025 13.7 0.0 0.39 9.8 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) ApbA PF02558.16 KFP06768.1 - 0.031 13.9 0.0 0.93 9.1 0.0 2.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA PglD_N PF17836.1 KFP06768.1 - 0.048 14.3 0.0 1.2 9.8 0.0 2.6 2 0 0 2 2 2 0 PglD N-terminal domain UDPG_MGDP_dh_N PF03721.14 KFP06768.1 - 0.055 13.0 0.6 2.3 7.7 0.1 2.6 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 KFP06768.1 - 0.064 13.1 0.0 1.4 8.7 0.1 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 KFP06768.1 - 0.15 10.9 1.3 4.7 5.9 0.1 2.7 2 1 1 3 3 3 0 Tryptophan halogenase NAD_binding_7 PF13241.6 KFP06768.1 - 0.15 12.5 1.4 4 7.9 0.0 2.9 2 1 0 3 3 3 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KFP06768.1 - 0.96 8.7 3.7 1.1 8.5 0.0 2.5 2 1 1 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1744 PF08490.12 KFP06769.1 - 2.5e-151 503.8 0.0 4e-151 503.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KFP06769.1 - 4.8e-96 321.8 0.1 1.8e-95 319.9 0.2 2.0 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KFP06769.1 - 2.1e-14 53.1 0.3 1.1e-12 47.4 0.3 3.4 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KFP06769.1 - 1.6e-08 34.5 0.4 6.2e-08 32.6 0.4 2.0 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KFP06769.1 - 1.4e-06 28.4 0.2 1.3e-05 25.3 0.1 2.8 2 1 0 2 2 2 1 RNase_H superfamily APP_N PF02177.16 KFP06769.1 - 0.039 14.3 0.3 0.14 12.5 0.3 2.0 1 0 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding DUF3198 PF11433.8 KFP06769.1 - 0.095 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3198) MAJIN PF15077.6 KFP06770.1 - 1e-12 48.4 0.1 1.3e-12 48.1 0.1 1.2 1 0 0 1 1 1 1 Membrane-anchored junction protein Phospholip_A2_2 PF05826.12 KFP06771.1 - 1.3e-20 73.4 0.4 1.8e-20 72.9 0.4 1.2 1 0 0 1 1 1 1 Phospholipase A2 SKICH PF17751.1 KFP06772.1 - 6.8e-28 97.2 0.1 1.6e-27 96.1 0.1 1.6 1 0 0 1 1 1 1 SKICH domain Exo_endo_phos PF03372.23 KFP06772.1 - 4.2e-11 42.8 0.1 6.5e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HECW_N PF16562.5 KFP06772.1 - 0.041 13.7 0.6 0.11 12.3 0.0 2.1 3 0 0 3 3 3 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 Smoothelin PF12510.8 KFP06773.1 - 1.8e-40 136.7 39.2 2.3e-18 66.0 11.2 3.7 3 0 0 3 3 3 3 Smoothelin cytoskeleton protein CH PF00307.31 KFP06773.1 - 7.3e-23 80.8 0.0 1.4e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFP06773.1 - 1.7e-06 27.8 0.0 3.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain Morc6_S5 PF17942.1 KFP06774.1 - 1.6e-23 83.3 0.9 1.8e-16 60.4 0.0 2.5 2 0 0 2 2 2 2 Morc6 ribosomal protein S5 domain 2-like HATPase_c_3 PF13589.6 KFP06774.1 - 5.2e-20 71.7 0.0 1.4e-19 70.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-CW PF07496.15 KFP06774.1 - 1.2e-15 57.2 4.2 2.9e-15 56.0 4.2 1.7 1 0 0 1 1 1 1 CW-type Zinc Finger XhlA PF10779.9 KFP06774.1 - 3.8 7.8 15.5 7.1 6.9 0.6 3.7 3 0 0 3 3 3 0 Haemolysin XhlA RGS12_us1 PF16613.5 KFP06774.1 - 6.8 7.0 15.9 0.15 12.3 4.4 2.7 2 0 0 2 2 2 0 Unstructured region of RGS12 ERM PF00769.19 KFP06777.1 - 4.9e-33 115.0 50.0 4.9e-33 115.0 50.0 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_M PF00373.18 KFP06777.1 - 3e-27 95.4 0.9 3e-27 95.4 0.9 3.0 2 1 1 3 3 3 1 FERM central domain FERM_C PF09380.10 KFP06777.1 - 5.8e-25 87.5 0.1 3e-24 85.2 0.0 2.2 3 0 0 3 3 3 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KFP06777.1 - 1.2e-09 38.0 0.1 4.8e-09 36.0 0.1 2.1 1 0 0 1 1 1 1 FERM N-terminal domain EF-hand_1 PF00036.32 KFP06778.1 - 0.0013 18.1 0.3 0.042 13.4 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KFP06778.1 - 0.0049 16.7 1.4 1 9.3 0.1 2.7 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP06778.1 - 0.0056 16.1 0.5 0.15 11.6 0.1 2.3 2 0 0 2 2 2 1 EF hand DEK_C PF08766.11 KFP06778.1 - 0.037 13.9 0.5 1.3 9.0 0.1 2.2 2 0 0 2 2 2 0 DEK C terminal domain EF-hand_6 PF13405.6 KFP06778.1 - 0.064 13.2 0.1 2.1 8.5 0.0 2.6 2 1 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 KFP06778.1 - 0.13 12.7 0.3 15 6.1 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair U79_P34 PF03064.16 KFP06778.1 - 0.14 11.5 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 zf-CCCH PF00642.24 KFP06779.1 - 3.6e-09 36.3 2.4 6.3e-09 35.5 2.4 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KFP06779.1 - 2e-08 33.8 2.9 4.1e-08 32.9 2.9 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-U1 PF06220.12 KFP06779.1 - 6.8e-08 32.1 3.9 1.4e-07 31.1 3.9 1.6 1 0 0 1 1 1 1 U1 zinc finger zf_CCCH_4 PF18345.1 KFP06779.1 - 4.5e-07 29.7 4.3 8.2e-07 28.9 4.3 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 KFP06779.1 - 0.0007 20.0 2.9 0.0013 19.2 2.9 1.4 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-C2H2_jaz PF12171.8 KFP06779.1 - 0.45 10.9 7.6 4.6 7.6 7.6 2.4 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KFP06779.1 - 2.4 9.2 6.1 2 9.4 1.8 2.5 2 1 0 2 2 2 0 C2H2-type zinc finger UCR_UQCRX_QCR9 PF05365.12 KFP06780.1 - 1.4e-25 89.0 0.1 1.5e-25 88.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Myotub-related PF06602.14 KFP06781.1 - 7.4e-139 462.6 0.1 1e-138 462.1 0.1 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 KFP06781.1 - 0.00066 19.3 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFP06781.1 - 0.0028 17.4 0.0 0.0061 16.4 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP06781.1 - 0.0037 17.3 0.0 0.0065 16.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KFP06781.1 - 0.13 11.8 0.0 0.36 10.4 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family HORMA PF02301.18 KFP06782.1 - 2.3e-48 164.6 0.0 3.1e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 HORMA domain LIF_OSM PF01291.17 KFP06783.1 - 3e-29 102.3 0.6 3.3e-29 102.1 0.6 1.0 1 0 0 1 1 1 1 LIF / OSM family ACT_7 PF13840.6 KFP06784.1 - 5.3e-27 93.4 0.2 6.1e-19 67.6 0.1 2.3 2 0 0 2 2 2 2 ACT domain Castor1_N PF18700.1 KFP06784.1 - 3.7e-19 68.3 4.0 8.3e-17 60.8 0.6 2.7 3 0 0 3 3 3 2 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain RabGAP-TBC PF00566.18 KFP06785.1 - 1.1e-54 185.3 0.0 1.6e-54 184.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain LRRCT PF01463.24 KFP06785.1 - 0.14 12.7 2.1 26 5.7 0.1 3.5 3 0 0 3 3 3 0 Leucine rich repeat C-terminal domain KASH_CCD PF14662.6 KFP06786.1 - 0.001 19.0 11.9 0.001 19.0 11.9 3.9 1 1 2 3 3 3 1 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 KFP06786.1 - 0.0043 16.4 75.7 0.04 13.3 24.1 4.2 2 1 2 4 4 4 3 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 KFP06786.1 - 0.077 13.0 81.0 0.033 14.2 21.0 4.9 2 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SKA2 PF16740.5 KFP06786.1 - 5.2 6.9 50.1 0.43 10.4 8.0 5.1 2 1 3 5 5 5 0 Spindle and kinetochore-associated protein 2 ATG16 PF08614.11 KFP06786.1 - 7.2 6.8 80.0 0.016 15.4 25.5 4.2 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) zf-RING_2 PF13639.6 KFP06787.1 - 7.8e-12 45.3 9.0 1.9e-11 44.1 9.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFP06787.1 - 2.7e-09 36.6 5.6 2.7e-09 36.6 5.6 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFP06787.1 - 2.9e-08 33.4 8.7 6.2e-08 32.4 8.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFP06787.1 - 2.3e-07 31.0 9.6 6.5e-06 26.4 9.6 2.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFP06787.1 - 3.4e-07 30.0 6.1 8.4e-07 28.8 6.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP06787.1 - 4.7e-06 26.5 6.0 9.2e-06 25.5 6.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFP06787.1 - 1.8e-05 24.6 3.1 1.8e-05 24.6 3.1 2.3 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFP06787.1 - 0.00062 19.6 7.9 0.00078 19.2 6.9 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFP06787.1 - 0.00063 19.6 4.0 0.0012 18.6 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 KFP06787.1 - 0.0075 16.3 2.2 0.021 14.9 2.2 1.8 1 0 0 1 1 1 1 Zinc-finger zf-ANAPC11 PF12861.7 KFP06787.1 - 0.085 12.9 5.2 0.24 11.5 5.2 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger CRAL_TRIO PF00650.20 KFP06788.1 - 2e-42 144.6 0.0 2.6e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFP06788.1 - 5.7e-06 26.5 0.0 9.9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Gal-3-0_sulfotr PF06990.11 KFP06789.1 - 5e-154 513.0 2.2 5.6e-154 512.9 2.2 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_3 PF13469.6 KFP06789.1 - 0.0014 19.1 0.3 0.0044 17.4 0.1 1.8 2 0 0 2 2 2 1 Sulfotransferase family Pescadillo_N PF06732.11 KFP06790.1 - 5.5e-114 380.3 1.6 5.5e-114 380.3 1.6 2.3 2 1 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 KFP06790.1 - 2.4e-08 34.2 0.0 5.2e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain TRAP_alpha PF03896.16 KFP06790.1 - 0.079 12.1 5.2 4.2 6.5 6.9 2.3 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit CENP-B_dimeris PF09026.10 KFP06790.1 - 0.25 11.8 13.3 0.59 10.5 13.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.14 KFP06790.1 - 1.6 6.9 21.4 3.1 6.0 21.4 1.4 1 0 0 1 1 1 0 CDC45-like protein Merozoite_SPAM PF07133.11 KFP06790.1 - 3.3 7.7 37.8 0.03 14.3 24.9 2.3 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) DNA_pol_phi PF04931.13 KFP06790.1 - 4 5.4 21.8 6.6 4.7 21.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cobalamin_bind PF01122.19 KFP06791.1 - 8.5e-72 241.7 0.0 9.3e-72 241.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic cobalamin-binding protein DUF533 PF04391.12 KFP06791.1 - 0.05 13.2 0.0 0.26 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Peptidase_C69 PF03577.15 KFP06792.1 - 1.1e-07 31.2 0.1 1.4e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family C69 AAT PF03417.16 KFP06792.1 - 0.084 12.6 0.0 0.48 10.1 0.0 2.1 1 1 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase TetR_C_15 PF17918.1 KFP06792.1 - 0.83 10.4 3.9 8.2 7.2 0.3 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain zf-H2C2_2 PF13465.6 KFP06793.1 - 1.7e-11 44.0 5.3 3e-06 27.4 0.9 4.7 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFP06793.1 - 6.3e-10 39.0 34.2 6.3e-05 23.2 1.0 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP06793.1 - 6.2e-05 23.5 30.2 0.014 16.1 0.9 3.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFP06793.1 - 0.01 16.2 6.9 0.075 13.3 2.6 2.8 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 KFP06793.1 - 0.11 12.6 14.8 0.7 10.0 3.5 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-LYAR PF08790.11 KFP06793.1 - 0.39 10.7 3.8 13 5.8 0.7 3.1 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger FOXP-CC PF16159.5 KFP06793.1 - 2.9 8.6 8.8 1.3 9.7 1.5 3.1 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 KFP06793.1 - 5.6 7.4 9.8 9.4 6.7 2.2 3.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KFP06794.1 - 8.9e-14 51.1 8.0 2.7e-08 33.8 0.9 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP06794.1 - 2.8e-11 43.3 6.8 1e-09 38.3 0.7 2.3 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP06794.1 - 2.1e-10 40.5 6.1 8.5e-05 23.1 0.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFP06794.1 - 1.7e-08 34.6 3.7 0.00011 22.4 0.3 2.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP06794.1 - 2.5e-08 34.0 0.9 0.0017 18.6 0.1 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFP06794.1 - 9.2e-05 22.7 2.0 0.00013 22.2 2.0 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 KFP06794.1 - 0.00019 21.2 0.2 0.39 10.6 0.1 2.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (1 copy) Rad50_zn_hook PF04423.14 KFP06794.1 - 0.00038 20.2 1.2 0.048 13.5 0.1 2.2 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-C2H2_6 PF13912.6 KFP06794.1 - 0.00043 20.2 4.4 0.18 11.9 0.2 2.4 2 1 0 2 2 2 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFP06794.1 - 0.0014 18.7 0.6 0.0021 18.1 0.6 1.3 1 1 0 1 1 1 1 Zinc ribbon domain zf-LYAR PF08790.11 KFP06794.1 - 0.002 18.0 2.9 0.19 11.7 0.3 2.2 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger Zn-C2H2_12 PF18112.1 KFP06794.1 - 0.0022 18.4 2.4 0.17 12.4 0.3 2.4 2 1 0 2 2 2 1 Autophagy receptor zinc finger-C2H2 domain zf-H2C2_5 PF13909.6 KFP06794.1 - 0.0025 17.5 2.7 0.046 13.5 0.4 2.3 2 0 0 2 2 2 1 C2H2-type zinc-finger domain DUF2256 PF10013.9 KFP06794.1 - 0.0025 17.9 0.3 0.39 10.9 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2256) Prok-RING_1 PF14446.6 KFP06794.1 - 0.0036 17.2 0.9 0.51 10.3 0.1 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-HYPF PF07503.12 KFP06794.1 - 0.0059 16.3 1.4 0.019 14.7 1.3 1.8 1 1 1 2 2 2 1 HypF finger zf-C2H2_2 PF12756.7 KFP06794.1 - 0.0067 16.8 0.7 0.48 10.8 0.2 2.0 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) YacG PF03884.14 KFP06794.1 - 0.0069 16.1 1.0 1.6 8.5 0.1 2.2 2 0 0 2 2 2 1 DNA gyrase inhibitor YacG ADK_lid PF05191.14 KFP06794.1 - 0.0072 16.3 1.6 0.023 14.7 1.6 2.0 1 1 0 1 1 1 1 Adenylate kinase, active site lid zf_UBZ PF18439.1 KFP06794.1 - 0.0082 15.7 1.9 0.38 10.4 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger Prok-RING_4 PF14447.6 KFP06794.1 - 0.0093 15.8 1.1 0.12 12.2 1.1 2.1 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 DZR PF12773.7 KFP06794.1 - 0.0095 15.9 0.9 0.013 15.5 0.9 1.2 1 0 0 1 1 1 1 Double zinc ribbon BolA PF01722.18 KFP06794.1 - 0.01 16.1 0.4 0.18 12.1 0.2 1.9 1 1 1 2 2 2 1 BolA-like protein zf-C2H2_11 PF16622.5 KFP06794.1 - 0.01 15.6 1.1 1.8 8.4 0.1 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-ISL3 PF14690.6 KFP06794.1 - 0.011 16.3 4.4 0.8 10.4 0.6 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 UBZ_FAAP20 PF15750.5 KFP06794.1 - 0.016 15.1 0.8 1.1 9.2 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger FYDLN_acid PF09538.10 KFP06794.1 - 0.03 15.0 0.7 1.2 9.9 0.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-CGNR PF11706.8 KFP06794.1 - 0.032 14.1 2.7 1.2 9.0 0.3 2.1 2 0 0 2 2 2 0 CGNR zinc finger DUF2225 PF09986.9 KFP06794.1 - 0.045 13.5 1.2 0.81 9.4 0.4 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C3HC4_3 PF13920.6 KFP06794.1 - 0.047 13.5 0.9 0.17 11.8 0.9 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TRAF6_Z2 PF18048.1 KFP06794.1 - 0.049 13.7 1.6 3.7 7.7 0.1 2.2 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zinc_ribbon_4 PF13717.6 KFP06794.1 - 0.059 13.3 2.1 3.4 7.7 2.1 2.2 1 1 0 1 1 1 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 KFP06794.1 - 0.1 12.5 3.5 1.1 9.3 3.4 2.2 1 1 0 1 1 1 0 SprT-like zinc ribbon domain zf-C2HC_2 PF13913.6 KFP06794.1 - 0.17 11.9 3.8 7.1 6.7 0.4 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-TFIIB PF13453.6 KFP06794.1 - 0.17 11.3 1.3 0.87 9.0 1.3 2.0 1 1 0 1 1 1 0 Transcription factor zinc-finger TF_Zn_Ribbon PF08271.12 KFP06794.1 - 0.19 11.3 2.2 7.8 6.1 0.2 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_9 PF14369.6 KFP06794.1 - 0.22 11.8 5.2 1.3 9.3 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon DUF2072 PF09845.9 KFP06794.1 - 0.23 11.7 1.9 2.8 8.2 0.3 2.0 2 0 0 2 2 2 0 Zn-ribbon containing protein zf_C2H2_10 PF18414.1 KFP06794.1 - 0.24 11.0 3.2 0.93 9.1 0.4 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger zinc_ribbon_5 PF13719.6 KFP06794.1 - 0.4 10.5 3.3 9.1 6.1 0.3 2.1 2 0 0 2 2 2 0 zinc-ribbon domain SAND PF01342.21 KFP06795.1 - 1e-23 82.8 0.1 2.1e-23 81.8 0.1 1.5 1 0 0 1 1 1 1 SAND domain GFD1 PF17331.2 KFP06795.1 - 1.3 9.3 5.4 2.7 8.3 5.4 1.6 1 0 0 1 1 1 0 GFD1 mRNA transport factor DUF948 PF06103.11 KFP06795.1 - 2.9 8.2 8.1 1.2 9.5 2.9 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) YTH PF04146.15 KFP06796.1 - 1.9e-40 138.5 0.3 8.2e-40 136.5 0.3 1.9 1 1 0 1 1 1 1 YT521-B-like domain PMSR PF01625.21 KFP06797.1 - 5.8e-20 72.0 0.5 6.6e-20 71.8 0.5 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Metal_resist PF13801.6 KFP06797.1 - 0.014 15.6 2.3 0.018 15.2 2.3 1.1 1 0 0 1 1 1 0 Heavy-metal resistance Cyt_b-c1_8 PF10890.8 KFP06797.1 - 0.1 13.0 0.4 0.22 11.9 0.4 1.7 1 1 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 HLH PF00010.26 KFP06798.1 - 4.1e-12 45.9 0.0 5.8e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain E2F_CC-MB PF16421.5 KFP06799.1 - 1.8e-30 105.1 0.1 2.9e-30 104.5 0.1 1.3 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 KFP06799.1 - 3.3e-24 84.7 0.1 5.2e-24 84.1 0.1 1.3 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain TFIIS_M PF07500.14 KFP06800.1 - 1e-29 103.3 0.1 1.9e-29 102.4 0.1 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KFP06800.1 - 1.1e-18 66.8 7.1 2.3e-18 65.7 7.1 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KFP06800.1 - 3.7e-12 46.1 2.2 6e-12 45.4 0.8 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain 7tm_1 PF00001.21 KFP06801.1 - 6.5e-56 189.6 16.8 8e-56 189.3 16.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFP06801.1 - 1.7e-06 27.6 10.3 0.0007 19.0 1.0 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFP06801.1 - 8.7e-05 22.4 12.7 0.00018 21.4 12.7 1.5 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KFP06801.1 - 0.00055 19.4 15.0 0.049 13.0 15.0 2.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx SYS1 PF09801.9 KFP06801.1 - 0.038 14.1 0.5 0.038 14.1 0.5 2.4 2 1 0 2 2 2 0 Integral membrane protein S linking to the trans Golgi network DUF2207 PF09972.9 KFP06801.1 - 0.43 9.3 4.5 0.33 9.6 0.3 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) 7TM_GPCR_Srx PF10328.9 KFP06801.1 - 0.78 9.3 16.5 0.019 14.6 5.6 2.3 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx RCC1 PF00415.18 KFP06802.1 - 2.6e-49 165.6 10.2 4.5e-13 49.6 0.3 4.1 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFP06802.1 - 4.1e-12 45.6 21.5 0.033 14.0 1.6 5.2 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RVT_1 PF00078.27 KFP06803.1 - 0.14 11.7 0.0 0.32 10.5 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) FAM76 PF16046.5 KFP06804.1 - 5.1e-99 331.4 35.7 5.8e-99 331.2 35.7 1.0 1 0 0 1 1 1 1 FAM76 protein GHL13 PF14883.6 KFP06804.1 - 0.00096 18.3 3.5 0.0018 17.4 3.4 1.4 1 1 0 1 1 1 1 Hypothetical glycosyl hydrolase family 13 KASH_CCD PF14662.6 KFP06804.1 - 0.031 14.1 3.5 0.031 14.1 3.5 2.9 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH MPS2 PF17060.5 KFP06804.1 - 0.11 11.8 11.8 0.41 9.9 11.8 1.8 1 1 0 1 1 1 0 Monopolar spindle protein 2 CorA PF01544.18 KFP06804.1 - 0.12 11.6 3.2 0.16 11.2 3.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Jnk-SapK_ap_N PF09744.9 KFP06804.1 - 0.32 11.2 17.8 0.25 11.5 9.9 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF16 PF01519.16 KFP06804.1 - 1 9.9 10.1 0.56 10.7 7.0 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 PSII_Pbs31 PF18240.1 KFP06804.1 - 3.5 8.1 6.6 0.78 10.2 1.9 2.1 2 0 0 2 2 2 0 Photosystem II Psb31 protein TipAS PF07739.13 KFP06804.1 - 3.9 8.1 9.8 0.59 10.7 5.1 2.1 2 2 1 3 3 3 0 TipAS antibiotic-recognition domain Peptidase_C1 PF00112.23 KFP06805.1 - 4.3e-71 239.5 5.3 5.2e-71 239.2 5.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KFP06805.1 - 9.1e-09 35.6 0.2 1.6e-08 34.9 0.2 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KFP06805.1 - 0.0011 17.8 0.4 0.16 10.7 0.2 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Colicin_D PF11429.8 KFP06805.1 - 0.14 12.6 2.5 0.75 10.3 0.2 2.8 2 1 1 3 3 3 0 Colicin D Pkinase_Tyr PF07714.17 KFP06806.1 - 1.4e-92 309.7 0.0 1.7e-92 309.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP06806.1 - 6.1e-44 150.4 0.0 7.6e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFP06806.1 - 1.2e-26 92.6 0.2 2.5e-26 91.6 0.2 1.6 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 KFP06806.1 - 0.00084 19.2 0.1 0.0027 17.5 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain Haspin_kinase PF12330.8 KFP06806.1 - 0.00096 18.2 0.0 0.0015 17.5 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain SH3_1 PF00018.28 KFP06806.1 - 0.0042 16.7 0.3 0.019 14.6 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFP06806.1 - 0.0049 16.5 0.3 0.014 15.0 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain APH PF01636.23 KFP06806.1 - 0.048 13.6 0.0 0.61 10.0 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family WH2 PF02205.20 KFP06807.1 - 1.7e-08 34.0 0.0 3.2e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 WH2 motif WASH_WAHD PF11945.8 KFP06807.1 - 0.097 12.2 3.3 0.37 10.3 3.3 1.9 1 1 0 1 1 1 0 WAHD domain of WASH complex 7tm_1 PF00001.21 KFP06808.1 - 2e-38 132.2 20.3 2.6e-38 131.8 20.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP06808.1 - 0.0062 16.3 18.1 0.037 13.8 18.1 2.2 1 1 0 1 1 1 1 Olfactory receptor Corona_NSP4_C PF16348.5 KFP06808.1 - 0.016 16.0 0.0 0.043 14.6 0.0 1.7 1 0 0 1 1 1 0 Coronavirus nonstructural protein 4 C-terminus C2 PF00168.30 KFP06809.1 - 4.2e-35 120.1 0.0 1.9e-18 66.6 0.0 2.1 2 0 0 2 2 2 2 C2 domain DUF778 PF05608.12 KFP06810.1 - 8.5e-43 146.9 5.5 2.4e-21 77.0 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF778) WD40 PF00400.32 KFP06812.1 - 1.5e-23 82.7 5.6 2.1e-06 28.4 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat TPR_19 PF14559.6 KFP06812.1 - 2.4e-07 31.2 1.8 0.0018 18.7 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 KFP06812.1 - 5.3e-06 26.7 0.1 0.0065 16.8 0.2 4.4 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 KFP06812.1 - 6.3e-06 25.9 8.4 0.052 13.7 0.4 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFP06812.1 - 1.5e-05 25.0 2.2 0.032 14.6 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFP06812.1 - 1.5e-05 24.6 10.4 0.14 12.0 1.0 4.4 3 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP06812.1 - 2.6e-05 24.3 4.7 5.3e-05 23.4 4.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KFP06812.1 - 3.3e-05 24.4 0.8 0.35 11.8 0.1 2.8 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFP06812.1 - 4e-05 23.2 1.4 0.00023 20.8 0.9 2.2 2 0 0 2 2 2 1 TPR repeat TPR_6 PF13174.6 KFP06812.1 - 0.00044 20.7 0.3 0.31 11.8 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFP06812.1 - 0.061 14.0 2.8 8.9 7.0 0.1 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFP06812.1 - 0.23 11.6 0.6 1.6 8.9 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFP06812.1 - 0.3 11.4 1.1 9.8 6.7 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Na_H_Exchanger PF00999.21 KFP06813.1 - 5e-85 285.6 43.2 5.8e-85 285.4 43.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family OprF PF05736.11 KFP06813.1 - 0.077 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 OprF membrane domain NTP_transf_7 PF07984.12 KFP06814.1 - 3.8e-143 476.5 0.9 4.4e-143 476.3 0.9 1.0 1 0 0 1 1 1 1 Nucleotidyltransferase DUF4656 PF15551.6 KFP06815.1 - 1.7e-171 570.7 20.9 3e-169 563.3 20.9 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4656) CS PF04969.16 KFP06816.1 - 3.7e-19 69.5 0.1 1.5e-18 67.5 0.0 2.0 2 0 0 2 2 2 1 CS domain NuDC PF16273.5 KFP06816.1 - 9.6e-15 54.9 16.3 9.6e-15 54.9 16.3 3.1 2 2 1 3 3 3 1 Nuclear distribution C domain Nudc_N PF14050.6 KFP06816.1 - 3.7e-05 23.6 3.1 3.7e-05 23.6 3.1 1.9 2 1 0 2 2 2 1 N-terminal conserved domain of Nudc. DUF1682 PF07946.14 KFP06816.1 - 1.7 7.7 14.1 3.7 6.7 14.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Hormone_recep PF00104.30 KFP06817.1 - 2.2e-21 76.4 0.0 2.8e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor G-patch PF01585.23 KFP06818.1 - 2.7e-08 33.6 1.2 4.9e-08 32.7 1.2 1.5 1 0 0 1 1 1 1 G-patch domain Ribosomal_60s PF00428.19 KFP06818.1 - 0.18 12.4 9.9 0.38 11.4 9.9 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein 14-3-3 PF00244.20 KFP06819.1 - 2.7e-102 341.0 6.2 3.1e-102 340.8 6.2 1.0 1 0 0 1 1 1 1 14-3-3 protein Peptidase_C98 PF15499.6 KFP06819.1 - 0.039 13.4 0.1 0.065 12.7 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase FliM PF02154.15 KFP06819.1 - 0.11 12.4 0.0 0.35 10.7 0.0 1.7 1 1 1 2 2 2 0 Flagellar motor switch protein FliM SIKE PF05769.11 KFP06819.1 - 0.59 10.0 4.8 0.39 10.6 0.9 2.5 3 1 1 4 4 4 0 SIKE family DHHC PF01529.20 KFP06820.1 - 3.8e-36 124.2 10.4 3.8e-36 124.2 10.4 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4131 PF13567.6 KFP06820.1 - 0.35 10.5 4.8 5.5 6.6 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Mannosyl_trans2 PF04188.13 KFP06821.1 - 4.6e-135 451.4 5.4 5.7e-135 451.1 5.4 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) BAF250_C PF12031.8 KFP06822.1 - 6.9e-120 399.1 0.0 1.3e-119 398.3 0.0 1.4 1 0 0 1 1 1 1 SWI/SNF-like complex subunit BAF250/Osa ARID PF01388.21 KFP06822.1 - 3.2e-14 53.4 0.0 7.7e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Pkinase PF00069.25 KFP06823.1 - 3.3e-149 495.5 0.0 2e-76 256.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFP06823.1 - 2.6e-78 262.9 0.0 3.8e-41 141.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFP06823.1 - 1e-13 51.2 0.0 8.7e-07 28.5 0.0 3.2 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.14 KFP06823.1 - 5e-11 42.4 0.0 2.1e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFP06823.1 - 3.8e-09 35.8 0.0 0.00049 19.0 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase Haspin_kinase PF12330.8 KFP06823.1 - 1.3e-06 27.6 0.1 0.029 13.3 0.1 2.3 2 0 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 KFP06823.1 - 5.2e-05 23.3 0.0 0.3 11.0 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family FTA2 PF13095.6 KFP06823.1 - 0.00023 20.8 0.1 3.5 7.2 0.0 3.4 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 KFP06823.1 - 0.00099 18.7 0.0 0.29 10.6 0.0 2.8 3 0 0 3 3 3 1 PhoP regulatory network protein YrbL tRNA-synt_1f PF01921.18 KFP06823.1 - 0.0036 16.3 0.0 0.0071 15.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (K) Pkinase_C PF00433.24 KFP06823.1 - 0.0088 16.7 0.0 0.033 14.9 0.0 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain RIO1 PF01163.22 KFP06823.1 - 0.035 13.7 0.0 0.84 9.2 0.0 2.3 2 0 0 2 2 2 0 RIO1 family HMG14_17 PF01101.18 KFP06824.1 - 2.4e-25 89.3 21.1 2.8e-25 89.1 21.1 1.0 1 0 0 1 1 1 1 HMG14 and HMG17 Prenyltransf PF01255.19 KFP06825.1 - 2e-77 259.7 0.0 2.8e-77 259.2 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase AATase PF07247.12 KFP06825.1 - 0.036 12.6 0.0 0.052 12.1 0.0 1.1 1 0 0 1 1 1 0 Alcohol acetyltransferase RecX PF02631.16 KFP06825.1 - 0.32 11.4 7.2 0.93 10.0 0.1 2.6 2 1 0 2 2 2 0 RecX family CSD PF00313.22 KFP06826.1 - 2.5e-17 62.5 0.3 6.1e-17 61.2 0.3 1.6 1 1 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-CCHC PF00098.23 KFP06826.1 - 2.2e-07 30.7 11.1 3.6e-05 23.7 3.0 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 KFP06826.1 - 0.015 15.1 9.0 0.093 12.5 1.5 2.5 2 0 0 2 2 2 0 Zinc knuckle CusF_Ec PF11604.8 KFP06826.1 - 0.14 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF zf-CCHC_6 PF15288.6 KFP06826.1 - 0.27 11.1 7.0 3.9 7.4 0.8 2.5 2 0 0 2 2 2 0 Zinc knuckle Crystall PF00030.19 KFP06827.1 - 6.7e-131 426.8 0.0 2.9e-25 88.2 0.0 6.2 6 0 0 6 6 6 6 Beta/Gamma crystallin IL4_i_Ig PF18258.1 KFP06827.1 - 7.8e-12 45.2 2.5 1.8 8.8 0.0 7.6 5 2 2 7 7 7 4 Interleukin-4 inducing immunoglobulin-binding domain Ricin_B_lectin PF00652.22 KFP06827.1 - 1.1e-06 28.9 0.0 2.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Crystall_3 PF08964.10 KFP06827.1 - 0.00083 19.5 0.8 4.8 7.4 0.0 4.6 5 1 0 5 5 5 2 Beta/Gamma crystallin SEP PF08059.13 KFP06828.1 - 8.6e-20 71.1 0.3 2.3e-19 69.7 0.0 1.9 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 KFP06828.1 - 7.5e-11 42.1 0.0 7.3e-10 38.9 0.0 2.3 2 0 0 2 2 2 1 UBX domain Abhydrolase_4 PF08386.10 KFP06828.1 - 0.029 14.5 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 TAP-like protein Atg14 PF10186.9 KFP06828.1 - 0.035 13.2 2.2 0.062 12.4 2.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2730 PF10805.8 KFP06828.1 - 0.051 13.7 4.0 0.12 12.5 4.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) LRRFIP PF09738.9 KFP06828.1 - 0.069 12.6 5.7 0.11 11.9 5.7 1.3 1 0 0 1 1 1 0 LRRFIP family AAA_13 PF13166.6 KFP06828.1 - 0.15 10.7 2.3 0.22 10.1 2.3 1.1 1 0 0 1 1 1 0 AAA domain DUF16 PF01519.16 KFP06828.1 - 0.42 11.1 6.7 0.22 12.0 4.4 1.8 2 0 0 2 2 1 0 Protein of unknown function DUF16 Csm1_N PF18504.1 KFP06828.1 - 0.48 10.8 6.8 1.3 9.4 6.8 1.7 1 0 0 1 1 1 0 Csm1 N-terminal domain TMPIT PF07851.13 KFP06828.1 - 0.49 9.6 3.5 0.71 9.1 3.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein Fib_alpha PF08702.10 KFP06828.1 - 0.69 10.1 5.8 3.9 7.6 6.2 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KFP06828.1 - 1 9.4 5.0 1.9 8.5 5.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DivIC PF04977.15 KFP06828.1 - 1.3 8.9 5.6 3.4 7.5 5.6 1.7 1 0 0 1 1 1 0 Septum formation initiator FAM76 PF16046.5 KFP06828.1 - 6.5 6.0 7.5 11 5.3 7.5 1.2 1 0 0 1 1 1 0 FAM76 protein XhlA PF10779.9 KFP06828.1 - 7.2 6.9 7.8 8 6.7 5.0 2.4 1 1 1 2 2 2 0 Haemolysin XhlA SH3BGR PF04908.15 KFP06829.1 - 7.8e-38 128.6 0.0 9e-38 128.4 0.0 1.0 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 KFP06829.1 - 2.3e-07 30.9 0.0 3.7e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 KFP06829.1 - 0.11 13.0 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PI_PP_I PF18363.1 KFP06830.1 - 0.78 10.0 9.1 0.19 11.9 0.2 3.3 3 1 0 3 3 3 0 Phosphoinositide phosphatase insertion domain Gtr1_RagA PF04670.12 KFP06832.1 - 6.8e-63 212.1 2.4 8.9e-63 211.7 2.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KFP06832.1 - 0.024 14.1 0.1 0.037 13.5 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Roc PF08477.13 KFP06832.1 - 0.037 14.2 0.0 0.068 13.4 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase TSC22 PF01166.18 KFP06833.1 - 0.002 18.4 1.2 0.0028 18.0 1.2 1.3 1 0 0 1 1 1 1 TSC-22/dip/bun family HALZ PF02183.18 KFP06833.1 - 0.0089 16.2 0.4 0.018 15.2 0.4 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper ZapB PF06005.12 KFP06833.1 - 0.037 14.5 1.6 0.06 13.8 1.6 1.3 1 0 0 1 1 1 0 Cell division protein ZapB Connexin PF00029.19 KFP06834.1 - 3.7e-88 295.3 0.2 4.1e-88 295.1 0.2 1.0 1 0 0 1 1 1 1 Connexin APG6_N PF17675.1 KFP06834.1 - 0.39 11.2 7.6 0.58 10.7 7.6 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region zf-C2H2_jaz PF12171.8 KFP06835.1 - 7.3e-10 38.9 3.4 9.8e-10 38.5 3.4 1.2 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFP06835.1 - 0.00071 19.9 0.1 0.00092 19.5 0.1 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFP06835.1 - 0.005 17.2 1.6 0.007 16.7 1.6 1.2 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AKAP95 PF04988.12 KFP06835.1 - 0.032 14.5 0.1 0.036 14.3 0.1 1.2 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) TDRP PF15683.5 KFP06836.1 - 4.2e-05 23.6 0.0 7.5e-05 22.7 0.0 1.5 2 0 0 2 2 2 1 Testis development-related protein Pkinase PF00069.25 KFP06837.1 - 2.9e-52 177.6 0.0 1.2e-51 175.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP06837.1 - 1.6e-32 112.9 0.4 1e-22 80.7 0.1 2.9 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP06837.1 - 0.00081 18.3 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP06837.1 - 0.0028 17.6 0.2 0.033 14.1 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFP06837.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFP06837.1 - 0.041 13.2 0.0 0.097 12.0 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KFP06837.1 - 0.059 12.3 0.0 0.097 11.6 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KFP06837.1 - 0.11 12.1 0.0 0.37 10.4 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.11 KFP06837.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-RING_UBOX PF13445.6 KFP06838.1 - 1e-10 41.4 3.9 2.9e-10 40.0 3.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFP06838.1 - 1.4e-08 34.4 2.8 1.4e-08 34.4 2.8 3.0 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP06838.1 - 3e-08 33.4 3.4 3e-08 33.4 3.4 2.8 2 2 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP06838.1 - 3.3e-07 30.5 5.7 3.3e-07 30.5 5.7 2.7 2 1 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.6 KFP06838.1 - 5.3e-07 29.5 4.2 5.3e-07 29.5 4.2 2.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-B_box PF00643.24 KFP06838.1 - 1.4e-06 28.3 6.5 1.4e-06 28.3 6.5 3.4 4 0 0 4 4 3 1 B-box zinc finger zf-C3HC4_4 PF15227.6 KFP06838.1 - 5.7e-06 26.4 6.4 5.7e-06 26.4 6.4 3.1 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KFP06838.1 - 1.7e-05 24.6 7.8 1.7e-05 24.6 7.8 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KFP06838.1 - 0.00014 21.6 0.2 0.00014 21.6 0.2 2.2 2 0 0 2 2 2 1 zf-RING of BARD1-type protein DUF745 PF05335.13 KFP06838.1 - 0.0014 18.4 4.0 0.13 11.9 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF745) DUF5327 PF17261.2 KFP06838.1 - 0.0014 19.3 2.4 0.0026 18.5 2.4 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5327) SHE3 PF17078.5 KFP06838.1 - 0.017 14.9 0.4 0.035 13.8 0.2 1.5 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 SesA PF17107.5 KFP06838.1 - 0.097 12.9 1.8 0.18 12.0 1.8 1.4 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases YkyA PF10368.9 KFP06838.1 - 0.19 11.4 7.9 0.32 10.7 7.9 1.4 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein zf-RING_11 PF17123.5 KFP06838.1 - 0.31 10.8 6.2 1 9.2 6.2 2.0 1 0 0 1 1 1 0 RING-like zinc finger Cytochrom_B562 PF07361.11 KFP06838.1 - 0.81 10.4 3.4 3 8.5 0.1 2.2 1 1 1 2 2 2 0 Cytochrome b562 Zn-C2H2_12 PF18112.1 KFP06838.1 - 1 9.9 5.1 0.73 10.4 1.3 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_10 PF16685.5 KFP06838.1 - 7.4 6.8 15.3 0.24 11.6 3.3 2.9 2 1 0 2 2 2 0 zinc RING finger of MSL2 Cation_efflux PF01545.21 KFP06839.1 - 5.4e-18 65.5 1.6 6.1e-18 65.3 1.6 1.0 1 0 0 1 1 1 1 Cation efflux family Glyco_transf_64 PF09258.10 KFP06840.1 - 1.1e-81 273.7 0.0 3.5e-72 242.6 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 64 domain Exostosin PF03016.15 KFP06840.1 - 2.2e-58 197.8 0.0 3.1e-58 197.3 0.0 1.2 1 0 0 1 1 1 1 Exostosin family PAF-AH_p_II PF03403.13 KFP06841.1 - 2.9e-139 463.8 0.0 3.3e-139 463.6 0.0 1.0 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KFP06841.1 - 1.1e-09 37.5 0.0 2.6e-09 36.4 0.0 1.6 1 1 1 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KFP06841.1 - 1.4e-07 31.0 0.1 0.0086 15.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFP06841.1 - 9.6e-06 25.2 0.0 2.3e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase PF07224.11 KFP06841.1 - 1.5e-05 24.2 0.2 0.024 13.7 0.0 2.7 3 0 0 3 3 3 2 Chlorophyllase Abhydrolase_6 PF12697.7 KFP06841.1 - 5.1e-05 24.0 0.1 0.0023 18.6 0.0 2.3 1 1 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 KFP06841.1 - 0.00024 20.8 0.0 0.00058 19.6 0.0 1.8 1 1 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.7 KFP06841.1 - 0.00069 19.4 0.0 0.0015 18.4 0.0 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 KFP06841.1 - 0.00078 19.1 0.0 0.0019 17.8 0.0 1.5 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KFP06841.1 - 0.023 14.5 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KFP06841.1 - 0.024 14.3 0.0 0.041 13.5 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 KFP06841.1 - 0.025 14.5 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.13 KFP06841.1 - 0.038 13.9 0.0 0.085 12.7 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 KFP06841.1 - 0.18 11.4 0.1 0.44 10.2 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase HlyIII PF03006.20 KFP06842.1 - 1.5e-49 168.8 13.2 2.2e-49 168.2 13.2 1.3 1 0 0 1 1 1 1 Haemolysin-III related Frag1 PF10277.9 KFP06842.1 - 0.00021 20.9 4.0 0.00021 20.9 4.0 2.3 2 1 0 2 2 2 1 Frag1/DRAM/Sfk1 family Mito_fiss_reg PF05308.11 KFP06843.1 - 7.2e-71 239.2 1.2 8.5e-71 238.9 1.2 1.0 1 0 0 1 1 1 1 Mitochondrial fission regulator EF-hand_7 PF13499.6 KFP06844.1 - 0.0022 18.4 0.0 0.0076 16.7 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair DUF1322 PF07032.11 KFP06844.1 - 0.065 13.8 0.1 0.18 12.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1322) SPARC_Ca_bdg PF10591.9 KFP06844.1 - 0.068 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region PID PF00640.23 KFP06846.1 - 3e-13 50.0 0.1 3.7e-13 49.7 0.1 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID_2 PF14719.6 KFP06846.1 - 1.1e-12 48.2 0.0 1.2e-12 48.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFP06846.1 - 6.4e-07 29.6 0.0 8.5e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine-binding domain MIF PF01187.18 KFP06846.1 - 0.11 12.8 0.0 0.14 12.5 0.0 1.1 1 0 0 1 1 1 0 Macrophage migration inhibitory factor (MIF) Macoilin PF09726.9 KFP06847.1 - 0 1055.9 17.6 0 1055.7 17.6 1.0 1 0 0 1 1 1 1 Macoilin family DUF812 PF05667.11 KFP06847.1 - 2.8e-05 23.2 35.0 2.8e-05 23.2 35.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF812) HU-CCDC81_bac_2 PF18175.1 KFP06847.1 - 0.1 12.5 3.6 1.2 9.0 0.1 3.6 2 1 1 3 3 3 0 CCDC81-like prokaryotic HU domain 2 FPP PF05911.11 KFP06847.1 - 1.7 6.7 49.8 0.27 9.4 28.0 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Mto2_bdg PF12808.7 KFP06847.1 - 4.4 7.7 19.0 2.8 8.3 1.6 3.9 3 1 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region GLE1 PF07817.13 KFP06847.1 - 6.2 5.9 17.8 0.37 10.0 0.3 2.6 3 0 0 3 3 3 0 GLE1-like protein Ammonium_transp PF00909.21 KFP06848.1 - 4.7e-46 157.3 23.0 5.6e-46 157.0 23.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family UPF0220 PF05255.11 KFP06849.1 - 2.1e-46 157.5 5.7 2.4e-46 157.3 5.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) TMEM107 PF14995.6 KFP06849.1 - 5.3 7.5 7.5 0.7 10.3 0.1 2.4 2 1 1 3 3 3 0 Transmembrane protein RSRP PF17069.5 KFP06850.1 - 3.7e-53 181.0 81.0 5.2e-53 180.6 81.0 1.2 1 0 0 1 1 1 1 Arginine/Serine-Rich protein 1 SYF2 PF08231.12 KFP06851.1 - 1.2e-56 191.5 11.7 1.2e-56 191.5 11.7 1.6 2 0 0 2 2 2 1 SYF2 splicing factor FUSC-like PF12805.7 KFP06851.1 - 0.0017 17.5 0.2 0.0025 16.9 0.2 1.2 1 0 0 1 1 1 1 FUSC-like inner membrane protein yccS rve_3 PF13683.6 KFP06851.1 - 0.023 14.5 0.3 0.41 10.5 0.0 2.5 2 0 0 2 2 2 0 Integrase core domain ARD PF03079.14 KFP06851.1 - 7.9 6.6 10.0 0.7 10.1 0.8 2.3 1 1 2 3 3 3 0 ARD/ARD' family Runt PF00853.19 KFP06852.1 - 2.3e-53 179.2 0.7 3.5e-53 178.6 0.7 1.3 1 0 0 1 1 1 1 Runt domain RunxI PF08504.11 KFP06852.1 - 4.2e-45 152.5 5.9 1.1e-44 151.2 5.9 1.7 1 0 0 1 1 1 1 Runx inhibition domain GST_C_2 PF13410.6 KFP06854.1 - 4.4e-07 29.8 0.0 9.3e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFP06854.1 - 6.8e-05 23.2 0.0 0.00013 22.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFP06854.1 - 7.2e-05 23.0 0.0 0.00015 22.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFP06854.1 - 0.0068 16.6 0.1 0.034 14.4 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain PWI PF01480.17 KFP06855.1 - 4e-30 103.9 0.2 7.1e-30 103.2 0.2 1.4 1 0 0 1 1 1 1 PWI domain SR-25 PF10500.9 KFP06855.1 - 0.0038 16.9 30.9 0.0038 16.9 30.9 7.0 2 1 3 7 7 7 1 Nuclear RNA-splicing-associated protein ETRAMP PF09716.10 KFP06855.1 - 2.6 8.2 11.7 0.19 11.8 4.9 2.4 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF2976 PF11190.8 KFP06856.1 - 0.0079 16.0 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2976) SKG6 PF08693.10 KFP06856.1 - 0.013 14.9 1.5 0.022 14.2 1.5 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 KFP06856.1 - 0.023 14.4 1.8 0.033 14.0 1.8 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Peptidase_M56 PF05569.11 KFP06856.1 - 0.055 12.6 0.0 0.056 12.6 0.0 1.0 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF2207 PF09972.9 KFP06856.1 - 0.06 12.1 0.0 0.066 12.0 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Presenilin PF01080.17 KFP06856.1 - 0.061 12.1 0.2 0.073 11.8 0.2 1.1 1 0 0 1 1 1 0 Presenilin Amnionless PF14828.6 KFP06856.1 - 0.076 11.8 0.0 0.081 11.7 0.0 1.0 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 KFP06856.1 - 0.14 13.1 0.0 0.18 12.7 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain m04gp34like PF12216.8 KFP06856.1 - 0.14 11.7 0.2 0.17 11.5 0.2 1.1 1 0 0 1 1 1 0 Immune evasion protein Calcipressin PF04847.12 KFP06857.1 - 1e-60 204.7 0.6 1.4e-60 204.2 0.6 1.2 1 0 0 1 1 1 1 Calcipressin RRM_occluded PF16842.5 KFP06857.1 - 0.16 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Mg_trans_NIPA PF05653.14 KFP06858.1 - 3.8e-70 236.3 20.0 4.6e-70 236.1 20.0 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA 7TMR-DISM_7TM PF07695.11 KFP06858.1 - 0.15 11.9 34.0 0.14 12.0 19.0 2.5 1 1 1 2 2 2 0 7TM diverse intracellular signalling BatA PF07584.11 KFP06858.1 - 7.3 7.0 7.7 13 6.3 1.0 3.4 3 1 0 3 3 3 0 Aerotolerance regulator N-terminal CP2 PF04516.15 KFP06859.1 - 8.9e-86 286.9 0.0 1.2e-85 286.5 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Tissue_fac PF01108.17 KFP06860.1 - 1.4e-22 79.5 0.1 2.5e-22 78.8 0.1 1.4 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.10 KFP06860.1 - 1.2e-08 35.2 0.3 2.8e-08 34.0 0.3 1.7 1 1 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.21 KFP06860.1 - 0.00066 20.0 0.8 0.055 13.8 0.1 2.4 2 0 0 2 2 2 2 Fibronectin type III domain Tissue_fac PF01108.17 KFP06861.1 - 7.2e-24 83.7 0.1 7.7e-24 83.6 0.1 1.0 1 0 0 1 1 1 1 Tissue factor Pkinase_Tyr PF07714.17 KFP06862.1 - 8.8e-77 257.9 0.0 1.3e-76 257.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.19 KFP06862.1 - 4.2e-69 232.2 0.0 7e-69 231.4 0.0 1.4 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.25 KFP06862.1 - 2.3e-30 105.8 0.0 5.6e-30 104.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain fn3 PF00041.21 KFP06862.1 - 7.6e-24 83.9 8.6 5.4e-12 45.9 2.8 3.7 4 1 0 4 4 3 2 Fibronectin type III domain EphA2_TM PF14575.6 KFP06862.1 - 3.2e-19 69.6 0.0 8e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SAM_1 PF00536.30 KFP06862.1 - 9.3e-17 61.2 0.0 1.9e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP06862.1 - 2.4e-15 56.4 0.0 6.5e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pur_ac_phosph_N PF16656.5 KFP06862.1 - 2.9e-06 27.8 1.8 0.00016 22.2 2.4 2.5 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain SusE PF14292.6 KFP06862.1 - 3.1e-05 24.1 0.6 0.031 14.5 0.6 2.8 3 0 0 3 3 3 2 SusE outer membrane protein Ephrin_rec_like PF07699.13 KFP06862.1 - 0.0053 16.5 3.4 0.0053 16.5 3.4 2.8 3 1 0 3 3 2 1 Putative ephrin-receptor like Interfer-bind PF09294.10 KFP06862.1 - 0.0086 16.4 0.3 0.045 14.1 0.6 2.0 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III Y_Y_Y PF07495.13 KFP06862.1 - 0.35 10.9 2.0 5.9 6.9 1.8 2.4 2 0 0 2 2 2 0 Y_Y_Y domain zf-C2H2 PF00096.26 KFP06863.1 - 6.3e-28 95.7 40.3 7.9e-05 22.9 1.3 6.6 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP06863.1 - 8.3e-26 89.2 44.7 1.5e-07 31.5 0.5 7.4 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP06863.1 - 1.1e-17 63.1 37.3 0.0077 17.0 0.9 7.0 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFP06863.1 - 2.5e-10 40.5 22.2 0.00021 21.6 5.1 4.0 1 1 3 4 4 4 4 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KFP06863.1 - 5.2e-05 23.4 26.5 0.03 14.6 1.8 6.6 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP06863.1 - 0.0053 16.7 1.2 0.0053 16.7 1.2 5.6 6 0 0 6 6 6 3 C2H2-type zinc finger Marek_A PF02124.15 KFP06863.1 - 0.0079 16.1 1.8 0.34 10.7 0.2 2.7 2 1 1 3 3 3 1 Marek's disease glycoprotein A zf-C2H2_aberr PF17017.5 KFP06863.1 - 0.42 10.7 19.7 3.6 7.7 1.5 5.1 1 1 4 5 5 5 0 Aberrant zinc-finger RhoGAP PF00620.27 KFP06864.1 - 1e-26 93.6 0.0 2.3e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 KFP06864.1 - 3.3e-17 62.8 0.0 5.3e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3449 PF11931.8 KFP06865.1 - 5.1e-78 261.1 5.2 6.4e-78 260.8 4.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) Telomere_Sde2_2 PF13297.6 KFP06865.1 - 6.8e-29 99.3 1.8 1.4e-28 98.2 1.8 1.6 1 0 0 1 1 1 1 Telomere stability C-terminal SF3A3 PF16837.5 KFP06865.1 - 2.4e-23 82.5 7.2 8.4e-23 80.7 7.2 2.0 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KFP06865.1 - 8.2e-16 57.6 1.2 1.7e-15 56.6 1.2 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain LIM PF00412.22 KFP06866.1 - 9.8e-49 163.4 70.5 2.4e-12 46.9 5.6 5.1 5 0 0 5 5 5 5 LIM domain Utp11 PF03998.13 KFP06867.1 - 8.5e-54 183.1 20.0 9.5e-54 182.9 20.0 1.0 1 0 0 1 1 1 1 Utp11 protein DUF2630 PF10944.8 KFP06867.1 - 0.85 10.1 4.8 0.26 11.8 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2630) dCMP_cyt_deam_1 PF00383.23 KFP06868.1 - 8.2e-19 67.4 0.3 4.3e-09 36.2 0.0 2.7 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFP06868.1 - 2.7e-12 46.6 0.3 4e-05 23.4 0.1 2.5 2 0 0 2 2 2 2 MafB19-like deaminase SNAD4 PF18750.1 KFP06868.1 - 0.0075 16.4 0.7 0.96 9.6 0.1 2.5 2 0 0 2 2 2 2 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 KFP06868.1 - 0.077 13.1 1.0 11 6.2 0.1 3.0 3 0 0 3 3 3 0 APOBEC3 NAD1 PF18778.1 KFP06868.1 - 0.47 10.5 3.4 12 5.9 0.8 2.5 2 1 0 2 2 2 0 Novel AID APOBEC clade 1 Mo25 PF08569.11 KFP06869.1 - 1.6e-132 441.8 11.8 1.8e-132 441.7 11.8 1.0 1 0 0 1 1 1 1 Mo25-like HEAT_2 PF13646.6 KFP06869.1 - 0.043 14.2 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 HEAT repeats WcbI PF18588.1 KFP06869.1 - 0.064 12.9 0.1 2 8.0 0.0 2.6 2 1 1 3 3 3 0 Polysaccharide biosynthesis enzyme WcbI JmjN PF02375.17 KFP06869.1 - 0.49 10.4 2.3 3.1 7.8 0.2 3.0 3 0 0 3 3 3 0 jmjN domain zf-HC5HC2H PF13771.6 KFP06870.1 - 2.6e-10 40.4 3.1 2.6e-10 40.4 3.1 2.2 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFP06870.1 - 1.3e-06 28.5 3.7 7.7e-06 26.0 3.6 2.2 1 1 0 1 1 1 1 PHD-zinc-finger like domain PHD PF00628.29 KFP06870.1 - 0.46 10.4 7.4 0.19 11.6 0.7 2.9 3 0 0 3 3 3 0 PHD-finger RCC1 PF00415.18 KFP06871.1 - 8.4e-62 205.6 25.8 5.8e-15 55.6 2.5 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFP06871.1 - 2.2e-33 113.3 31.3 5.5e-10 38.8 2.3 6.6 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KFP06871.1 - 1.8e-21 76.5 0.8 1.4e-19 70.4 0.2 2.3 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFP06871.1 - 1.9e-06 27.9 1.4 0.0067 16.5 0.1 3.3 2 1 1 3 3 3 2 BTB And C-terminal Kelch PQQ_3 PF13570.6 KFP06871.1 - 0.76 10.3 4.4 19 5.9 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain Arf PF00025.21 KFP06872.1 - 5.5e-52 175.7 0.0 6.4e-52 175.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KFP06872.1 - 3.7e-11 42.8 0.0 1.4e-08 34.4 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KFP06872.1 - 6.6e-11 42.5 0.0 8.6e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP06872.1 - 2.3e-09 37.1 0.0 3.2e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFP06872.1 - 8.4e-09 35.1 0.0 1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFP06872.1 - 8.8e-05 22.0 0.0 0.00012 21.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP06872.1 - 0.00015 21.8 0.0 0.00022 21.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arm PF00514.23 KFP06873.1 - 6.4e-88 286.4 17.1 1.2e-12 47.3 0.3 9.3 9 1 1 10 10 10 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 KFP06873.1 - 3.7e-24 84.0 2.4 9.6e-23 79.5 3.3 2.4 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 KFP06873.1 - 3.8e-24 84.7 1.3 1.4e-08 35.1 0.2 6.3 5 1 1 6 6 6 5 HEAT-like repeat HEAT_2 PF13646.6 KFP06873.1 - 7.6e-18 64.7 0.3 9.8e-07 29.1 0.0 6.3 3 2 4 8 8 8 3 HEAT repeats HEAT PF02985.22 KFP06873.1 - 1e-17 62.7 6.5 0.0032 17.6 0.0 6.8 7 0 0 7 7 6 3 HEAT repeat Adaptin_N PF01602.20 KFP06873.1 - 8.3e-09 34.5 0.1 1.5e-08 33.7 0.1 1.3 1 1 0 1 1 1 1 Adaptin N terminal region IBB PF01749.20 KFP06873.1 - 1.3e-07 32.0 0.8 3.2e-07 30.7 0.8 1.8 1 0 0 1 1 1 1 Importin beta binding domain Atx10homo_assoc PF09759.9 KFP06873.1 - 1.2e-05 25.3 1.9 1.8 8.7 0.0 4.8 3 1 3 6 6 6 2 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 KFP06873.1 - 1.2e-05 25.0 0.4 6.1 6.2 0.0 4.3 2 1 2 4 4 4 1 Armadillo-like V-ATPase_H_C PF11698.8 KFP06873.1 - 1.6e-05 25.0 0.6 1.3 9.2 0.1 4.3 4 1 1 5 5 5 1 V-ATPase subunit H Cnd1 PF12717.7 KFP06873.1 - 2.8e-05 24.2 0.4 0.29 11.2 0.0 3.4 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.14 KFP06873.1 - 7.1e-05 22.3 0.4 0.011 15.0 0.1 2.5 1 1 1 2 2 2 1 V-ATPase subunit H RasGEF_N_2 PF14663.6 KFP06873.1 - 0.019 15.4 0.1 14 6.2 0.0 3.8 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Mo25 PF08569.11 KFP06873.1 - 0.022 14.2 0.1 0.042 13.2 0.1 1.6 1 0 0 1 1 1 0 Mo25-like DRIM PF07539.12 KFP06873.1 - 0.1 10.9 0.1 5.6 5.1 0.0 2.4 2 0 0 2 2 2 0 Down-regulated in metastasis Proteasom_PSMB PF10508.9 KFP06873.1 - 0.13 10.7 0.5 0.83 8.1 0.1 2.4 2 2 0 2 2 2 0 Proteasome non-ATPase 26S subunit RPEL PF02755.15 KFP06873.1 - 0.14 11.9 0.2 23 4.9 0.1 2.7 2 0 0 2 2 2 0 RPEL repeat DUF1981 PF09324.10 KFP06873.1 - 0.17 11.8 0.5 2.5 8.0 0.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1981) DCB PF16213.5 KFP06873.1 - 0.21 11.2 0.8 1.2 8.8 0.0 2.4 3 0 0 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 CTNNBL PF08216.11 KFP06873.1 - 0.21 11.8 2.0 33 4.7 0.0 3.8 4 2 1 5 5 4 0 Catenin-beta-like, Arm-motif containing nuclear SPRY PF00622.28 KFP06875.1 - 4e-17 62.5 0.0 5.1e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 SPRY domain BTB_2 PF02214.22 KFP06876.1 - 1.8e-18 66.7 0.1 4.5e-18 65.4 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KFP06876.1 - 0.00094 19.3 0.0 0.0024 18.0 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain RNase_H2-Ydr279 PF09468.10 KFP06877.1 - 9.1e-14 51.9 1.6 1.7e-13 51.1 1.6 1.4 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KFP06877.1 - 3.2e-12 46.5 0.0 7.2e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain HD_2 PF12917.7 KFP06877.1 - 0.063 13.0 0.8 0.11 12.2 0.3 1.7 2 0 0 2 2 2 0 HD containing hydrolase-like enzyme FAM124 PF15067.6 KFP06878.1 - 3.2e-108 360.8 0.0 5e-108 360.2 0.0 1.3 1 0 0 1 1 1 1 FAM124 family Serpin PF00079.20 KFP06879.1 - 6.3e-91 305.4 1.6 7.1e-91 305.3 1.6 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) WD40 PF00400.32 KFP06880.1 - 6.5e-21 74.3 14.1 3.7e-07 30.7 1.3 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat FYVE PF01363.21 KFP06880.1 - 2.3e-14 53.3 7.8 5.1e-14 52.2 7.8 1.6 1 0 0 1 1 1 1 FYVE zinc finger ANAPC4_WD40 PF12894.7 KFP06880.1 - 2.2e-06 27.8 0.1 0.19 12.0 0.0 3.8 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KFP06880.1 - 3.3e-05 22.8 0.5 0.37 9.5 0.0 3.4 3 2 1 4 4 4 2 Nup133 N terminal like FYVE_2 PF02318.16 KFP06880.1 - 0.041 14.1 4.3 0.096 12.9 4.3 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger DZR PF12773.7 KFP06880.1 - 0.1 12.7 7.5 0.86 9.7 7.5 2.5 1 1 0 1 1 1 0 Double zinc ribbon DUF2688 PF10892.8 KFP06880.1 - 0.21 11.1 5.0 0.71 9.4 5.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2688) DiS_P_DiS PF06750.13 KFP06880.1 - 6.3 7.0 7.3 47 4.2 6.5 2.7 2 1 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain adh_short PF00106.25 KFP06881.1 - 3.4e-27 95.2 0.3 4.4e-26 91.6 0.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP06881.1 - 1.4e-19 70.6 0.1 1.7e-18 67.0 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP06881.1 - 1.4e-10 41.4 0.1 2.4e-10 40.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFP06881.1 - 1.4e-08 34.5 0.0 1.8e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFP06881.1 - 5.4e-05 22.7 0.1 7.8e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 KFP06881.1 - 0.00018 21.0 0.1 0.0054 16.1 0.1 2.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KFP06881.1 - 0.0012 18.8 1.6 0.0053 16.7 0.7 2.4 1 1 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KFP06881.1 - 0.066 12.3 0.1 0.098 11.8 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein LDcluster4 PF18306.1 KFP06881.1 - 0.081 12.5 0.1 0.25 10.9 0.1 1.7 2 0 0 2 2 2 0 SLOG cluster4 family Glyco_transf_4 PF13439.6 KFP06881.1 - 0.13 12.3 0.0 0.38 10.7 0.0 1.7 2 0 0 2 2 2 0 Glycosyltransferase Family 4 HMA PF00403.26 KFP06882.1 - 1.8e-69 230.1 0.1 2.8e-12 46.9 0.0 6.7 6 0 0 6 6 6 6 Heavy-metal-associated domain Hydrolase PF00702.26 KFP06882.1 - 2.5e-61 207.6 0.8 4.9e-61 206.7 0.8 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFP06882.1 - 1.1e-46 158.6 3.1 1.1e-46 158.6 3.1 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFP06882.1 - 1.6e-07 31.4 2.8 2.3e-05 24.2 0.4 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KFP06882.1 - 0.0011 19.0 0.9 0.018 15.1 0.2 3.0 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFP06882.1 - 0.0018 18.4 0.2 0.0054 16.8 0.2 1.8 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase RRM_3 PF08777.11 KFP06882.1 - 0.0072 16.4 0.0 0.5 10.4 0.0 3.5 3 0 0 3 3 3 1 RNA binding motif HAD PF12710.7 KFP06882.1 - 0.026 14.9 0.1 0.061 13.7 0.1 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SapB_2 PF03489.17 KFP06882.1 - 0.027 14.6 0.9 0.084 13.0 0.3 2.3 2 0 0 2 2 1 0 Saposin-like type B, region 2 DUF2200 PF09966.9 KFP06882.1 - 0.21 11.8 2.6 17 5.6 0.0 3.8 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2200) GFA PF04828.14 KFP06882.1 - 0.72 10.2 7.7 18 5.8 0.1 4.5 5 0 0 5 5 5 0 Glutathione-dependent formaldehyde-activating enzyme DUF2688 PF10892.8 KFP06882.1 - 6.1 6.4 7.6 3.5 7.2 0.2 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2688) ALG11_N PF15924.5 KFP06883.1 - 1.1e-91 306.6 0.2 1.4e-91 306.2 0.2 1.1 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KFP06883.1 - 5.5e-29 100.9 0.0 1.1e-28 100.0 0.0 1.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFP06883.1 - 9.2e-14 52.0 0.0 2e-13 50.9 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KFP06883.1 - 0.00029 21.2 0.0 0.00052 20.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFP06883.1 - 0.0041 17.1 0.0 0.0094 16.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Pkinase PF00069.25 KFP06884.1 - 1.2e-57 195.2 0.0 2e-57 194.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP06884.1 - 4.4e-42 144.2 0.0 7.2e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP06884.1 - 8.3e-07 28.6 0.0 1.4e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP06884.1 - 0.026 13.3 0.2 0.11 11.2 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 KFP06884.1 - 0.11 11.9 0.7 0.22 10.8 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family LPD24 PF18839.1 KFP06884.1 - 0.12 12.7 0.4 12 6.2 0.1 2.5 2 0 0 2 2 2 0 Large polyvalent protein associated domain 24 Pentapeptide_4 PF13599.6 KFP06885.1 - 0.0051 17.0 0.0 0.12 12.6 0.0 2.0 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) DUF2924 PF11149.8 KFP06885.1 - 0.62 10.5 3.8 3.1 8.2 3.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2924) CKAP2_C PF15297.6 KFP06886.1 - 1.1e-73 248.3 30.6 7.6e-49 166.7 5.6 3.9 3 2 1 4 4 4 2 Cytoskeleton-associated protein 2 C-terminus EAP30 PF04157.16 KFP06887.1 - 8.3e-43 146.4 1.2 1.2e-42 145.8 1.2 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 KFP06887.1 - 2.6e-14 53.2 0.0 5.1e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 KFP06887.1 - 0.00045 20.1 0.0 0.0014 18.5 0.0 1.8 1 0 0 1 1 1 1 GRAM domain BBL5 PF07289.11 KFP06887.1 - 0.037 13.1 0.1 0.15 11.1 0.0 1.9 2 0 0 2 2 2 0 Bardet-Biedl syndrome 5 protein TssO PF17561.2 KFP06887.1 - 0.045 13.9 1.4 0.079 13.1 1.4 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssO PH_TFIIH PF08567.11 KFP06887.1 - 0.068 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain MA3 PF02847.17 KFP06887.1 - 0.11 12.5 0.8 0.64 10.0 0.1 2.2 2 0 0 2 2 2 0 MA3 domain TTRAP PF14203.6 KFP06887.1 - 0.17 11.9 4.6 0.22 11.5 1.9 2.1 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein YtxH PF12732.7 KFP06887.1 - 5.5 7.6 8.5 2.9 8.5 5.3 2.1 2 0 0 2 2 2 0 YtxH-like protein TSP_1 PF00090.19 KFP06888.1 - 2.6e-10 40.4 7.6 9.1e-10 38.6 7.6 2.1 1 0 0 1 1 1 1 Thrombospondin type 1 domain AJAP1_PANP_C PF15298.6 KFP06888.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Fibrinogen_C PF00147.18 KFP06889.1 - 1.6e-55 188.3 9.4 1.8e-55 188.2 9.4 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PTEN_C2 PF10409.9 KFP06891.1 - 7.1e-15 55.0 0.1 2.1e-14 53.4 0.1 1.8 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Ion_trans PF00520.31 KFP06891.1 - 1.2e-10 41.1 7.3 1.9e-10 40.4 7.3 1.3 1 0 0 1 1 1 1 Ion transport protein DSPc PF00782.20 KFP06891.1 - 4.9e-09 36.1 0.0 1.5e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFP06891.1 - 3.2e-05 24.1 0.0 5.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KFP06891.1 - 0.00013 21.6 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PKD_channel PF08016.12 KFP06891.1 - 0.016 13.9 2.7 0.026 13.2 2.7 1.4 1 0 0 1 1 1 0 Polycystin cation channel Y_phosphatase3 PF13350.6 KFP06891.1 - 0.063 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Mito_carr PF00153.27 KFP06892.1 - 2e-58 194.3 7.3 2.1e-19 69.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MRP-S31 PF15433.6 KFP06893.1 - 3.6e-69 233.9 7.3 3.9e-69 233.8 7.3 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 Sulfatase PF00884.23 KFP06894.1 - 4.3e-13 49.3 0.1 4.6e-13 49.2 0.1 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFP06894.1 - 9.5e-07 28.7 0.0 9.5e-07 28.7 0.0 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.12 KFP06894.1 - 0.0019 17.3 0.0 0.0019 17.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Amino_oxidase PF01593.24 KFP06895.1 - 1.8e-78 264.9 0.0 2.5e-78 264.4 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFP06895.1 - 1.9e-14 53.7 0.5 3.8e-14 52.7 0.5 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFP06895.1 - 3.5e-05 23.1 1.5 5.4e-05 22.5 1.5 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFP06895.1 - 9e-05 22.2 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFP06895.1 - 0.0024 17.1 0.1 0.0058 15.9 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFP06895.1 - 0.0042 16.4 1.1 0.012 14.9 0.4 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KFP06895.1 - 0.0065 15.2 0.4 0.015 14.0 0.4 1.7 1 1 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KFP06895.1 - 0.0089 15.3 0.1 0.016 14.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KFP06895.1 - 0.0092 15.3 0.2 0.015 14.5 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFP06895.1 - 0.0099 16.4 3.0 0.011 16.3 0.5 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KFP06895.1 - 0.016 14.5 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KFP06895.1 - 0.022 14.8 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 KFP06895.1 - 0.034 13.2 0.3 0.053 12.6 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KFP06895.1 - 0.046 13.1 0.4 0.067 12.5 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KFP06895.1 - 0.046 13.7 0.5 0.13 12.3 0.2 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KFP06895.1 - 0.12 11.4 0.6 0.36 9.8 0.3 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein FMO-like PF00743.19 KFP06895.1 - 0.18 10.2 0.0 0.26 9.6 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like 7tm_1 PF00001.21 KFP06896.1 - 9.7e-79 264.4 12.8 1.2e-78 264.1 12.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP06896.1 - 4.5e-17 62.3 7.8 8.2e-17 61.4 7.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP06896.1 - 1.8e-06 27.9 14.1 1.9e-05 24.5 7.3 3.0 3 0 0 3 3 3 2 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP06896.1 - 4.5e-06 26.5 13.8 4.5e-06 26.5 13.8 2.3 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx COX6B PF02297.17 KFP06897.1 - 1.5e-18 66.8 5.4 1.8e-18 66.5 5.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 KFP06897.1 - 0.1 12.9 2.8 0.32 11.3 2.7 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 KFP06897.1 - 0.12 12.6 2.3 0.31 11.2 2.0 1.8 1 1 1 2 2 2 0 CHCH domain EamA PF00892.20 KFP06898.1 - 1.2e-07 32.0 8.7 1.2e-07 32.0 8.7 2.7 2 1 0 2 2 2 1 EamA-like transporter family SLC35F PF06027.12 KFP06898.1 - 1.9e-05 24.3 24.6 2.8e-05 23.8 24.6 1.2 1 0 0 1 1 1 1 Solute carrier family 35 Ion_trans_2 PF07885.16 KFP06899.1 - 1.5e-24 85.7 13.5 8.5e-16 57.7 5.0 2.3 2 0 0 2 2 2 2 Ion channel Sulfotransfer_2 PF03567.14 KFP06900.1 - 2.7e-48 165.1 0.9 2.7e-48 165.1 0.9 1.4 2 0 0 2 2 2 1 Sulfotransferase family zf-CCCH PF00642.24 KFP06901.1 - 1.7e-13 50.1 17.3 0.00021 21.1 0.4 4.6 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KFP06901.1 - 6.6e-06 26.3 12.0 0.012 15.8 0.8 2.7 2 1 0 2 2 2 2 Zinc-finger containing family Torus PF16131.5 KFP06901.1 - 7.3e-06 26.6 18.9 0.022 15.5 0.1 4.3 2 2 2 4 4 4 4 Torus domain zf-CCCH_2 PF14608.6 KFP06901.1 - 1.1e-05 25.7 25.3 0.36 11.4 0.8 4.4 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 KFP06901.1 - 2.7e-05 23.8 2.1 2.7e-05 23.8 2.1 4.8 4 2 0 4 4 4 3 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFP06901.1 - 0.00045 20.2 32.1 0.015 15.3 3.2 6.7 4 4 0 4 4 4 2 Zinc finger domain DUF1936 PF09151.10 KFP06901.1 - 0.34 10.9 3.8 8 6.5 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) Ras PF00071.22 KFP06902.1 - 7.3e-19 67.9 0.0 8.1e-19 67.8 0.0 1.0 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 KFP06902.1 - 0.0011 18.9 0.0 0.0014 18.6 0.0 1.1 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KFP06902.1 - 0.0053 16.8 0.0 0.0065 16.5 0.0 1.1 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 KFP06902.1 - 0.007 15.9 0.0 0.0083 15.7 0.0 1.1 1 0 0 1 1 1 1 Ferrous iron transport protein B TPP_enzyme_M PF00205.22 KFP06902.1 - 0.0082 15.9 0.0 0.0093 15.7 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain GTP_EFTU PF00009.27 KFP06902.1 - 0.067 12.7 0.0 0.14 11.7 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain FERM_C PF09380.10 KFP06903.1 - 2.6e-25 88.7 0.4 5.4e-25 87.6 0.4 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 KFP06903.1 - 7.2e-15 55.4 0.2 1.3e-14 54.6 0.2 1.4 1 0 0 1 1 1 1 FERM central domain FA PF08736.11 KFP06903.1 - 5.2e-13 48.9 2.8 1.4e-12 47.5 1.7 2.2 2 0 0 2 2 2 1 FERM adjacent (FA) FERM_N PF09379.10 KFP06903.1 - 3.2e-10 39.8 0.0 8.7e-10 38.4 0.0 1.8 1 0 0 1 1 1 1 FERM N-terminal domain Pkinase PF00069.25 KFP06905.1 - 2.6e-72 243.3 0.0 3.1e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP06905.1 - 4.4e-54 183.5 0.0 5.5e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP06905.1 - 2.7e-05 23.1 0.0 4.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFP06905.1 - 0.0036 16.7 0.1 0.039 13.3 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFP06905.1 - 0.013 14.5 0.1 0.54 9.1 0.1 2.1 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KFP06905.1 - 0.033 14.1 0.0 5.2 6.9 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KFP06905.1 - 0.065 12.6 0.1 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ssDNA_DBD PF18333.1 KFP06905.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Non-canonical single-stranded DNA-binding domain IL6Ra-bind PF09240.10 KFP06906.1 - 1.8e-17 63.5 0.4 3.3e-17 62.7 0.4 1.4 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.10 KFP06906.1 - 9.9e-07 28.9 0.4 2.1e-06 27.9 0.4 1.5 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding Tissue_fac PF01108.17 KFP06906.1 - 2.3e-05 24.2 2.7 0.017 15.0 0.1 2.3 2 0 0 2 2 2 2 Tissue factor fn3 PF00041.21 KFP06906.1 - 0.0002 21.6 0.3 0.0058 17.0 0.1 2.5 2 1 0 2 2 2 1 Fibronectin type III domain IL2RB_N1 PF18707.1 KFP06906.1 - 0.074 13.6 0.5 0.074 13.6 0.5 1.7 2 0 0 2 2 2 0 Interleukin-2 receptor subunit beta N-terminal domain 1 IL4Ra_N PF09238.10 KFP06906.1 - 0.087 13.2 0.5 0.2 12.0 0.5 1.5 1 0 0 1 1 1 0 Interleukin-4 receptor alpha chain, N-terminal DOCK-C2 PF14429.6 KFP06907.1 - 1.2e-56 191.6 0.3 2.8e-55 187.1 0.1 2.5 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 KFP06907.1 - 2.4e-42 143.9 0.7 6e-42 142.6 0.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) PH PF00169.29 KFP06907.1 - 1.8e-11 44.5 0.6 5.3e-11 43.0 0.6 1.9 1 0 0 1 1 1 1 PH domain ApoLp-III PF07464.11 KFP06907.1 - 0.04 14.0 1.6 0.1 12.7 1.6 1.6 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Synapsin_N PF10581.9 KFP06907.1 - 4 7.5 4.9 7 6.7 0.1 3.0 3 0 0 3 3 3 0 Synapsin N-terminal WD40 PF00400.32 KFP06908.1 - 1.3e-24 86.0 9.4 0.00022 22.0 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP06908.1 - 7e-06 26.3 0.1 1.6 9.1 0.0 4.6 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KFP06908.1 - 0.12 12.5 0.1 4.9 7.2 0.0 3.3 2 2 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Kelch_1 PF01344.25 KFP06909.1 - 7.7e-56 185.5 7.6 1.2e-10 40.8 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFP06909.1 - 3.5e-36 122.3 6.0 1e-07 32.0 0.0 7.1 1 1 5 6 6 6 6 Kelch motif BACK PF07707.15 KFP06909.1 - 2e-27 95.3 0.0 4.5e-27 94.2 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 KFP06909.1 - 1.6e-24 84.9 4.8 3.7e-05 23.5 0.0 6.6 6 0 0 6 6 6 5 Kelch motif BTB PF00651.31 KFP06909.1 - 3e-24 85.4 0.2 1.2e-23 83.4 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.6 KFP06909.1 - 2.5e-23 81.8 4.3 3.3e-06 27.2 0.0 6.7 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KFP06909.1 - 1e-17 63.9 0.9 0.0015 18.5 0.0 5.7 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP06909.1 - 9.6e-11 41.4 13.0 0.0052 16.7 0.6 5.7 5 0 0 5 5 5 4 Kelch motif PQQ_3 PF13570.6 KFP06909.1 - 0.0062 17.0 5.7 9.5 6.9 0.0 5.0 6 0 0 6 6 6 1 PQQ-like domain SNF PF00209.18 KFP06911.1 - 4.8e-185 616.2 40.5 6e-185 615.9 40.5 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family PIRT PF15099.6 KFP06911.1 - 4.2 7.0 5.9 2.7 7.6 0.7 2.5 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family LRR_8 PF13855.6 KFP06912.1 - 4e-28 97.0 36.3 3.2e-13 49.2 7.7 4.1 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFP06912.1 - 1e-16 60.8 46.6 4.2e-06 27.0 3.2 4.7 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP06912.1 - 3.8e-10 39.8 2.3 1.6e-07 31.3 0.8 2.1 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFP06912.1 - 3.1e-08 33.1 33.1 0.27 11.9 2.7 7.4 7 0 0 7 7 7 4 Leucine Rich Repeat LRR_9 PF14580.6 KFP06912.1 - 3.2e-05 23.5 6.1 0.011 15.3 0.9 2.3 1 1 2 3 3 3 3 Leucine-rich repeat LRRNT PF01462.18 KFP06912.1 - 1.4 8.7 4.1 0.63 9.7 1.3 2.0 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 KFP06912.1 - 2.1 8.6 0.0 2.1 8.6 0.0 6.7 7 0 0 7 7 7 0 Leucine Rich repeat CH PF00307.31 KFP06913.1 - 1.1e-92 305.5 2.2 1.2e-25 89.8 0.1 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 KFP06913.1 - 4.1e-09 36.8 0.4 1.7e-08 34.8 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP06913.1 - 2.7e-07 29.7 2.4 3.8e-05 22.9 0.6 2.9 2 0 0 2 2 2 2 EF hand CAMSAP_CH PF11971.8 KFP06913.1 - 8e-06 25.6 0.1 0.00035 20.3 0.0 2.8 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_5 PF13202.6 KFP06913.1 - 0.00028 20.3 6.1 0.00042 19.7 0.2 3.7 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.6 KFP06913.1 - 0.0011 18.7 0.3 0.036 14.0 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 KFP06913.1 - 0.023 14.5 0.3 0.14 12.0 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain pair FYTT PF07078.11 KFP06914.1 - 0.00042 19.7 3.2 0.00051 19.5 3.2 1.1 1 0 0 1 1 1 1 Forty-two-three protein LRR_8 PF13855.6 KFP06915.1 - 1.3e-25 88.9 8.0 1.4e-10 40.8 1.0 3.4 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFP06915.1 - 1.1e-15 57.5 15.7 0.00033 21.0 3.2 5.3 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) CH PF00307.31 KFP06915.1 - 4.8e-10 39.6 0.0 9.1e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain LRR_1 PF00560.33 KFP06915.1 - 0.00013 22.1 17.0 2.8 8.8 0.3 7.7 7 1 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.6 KFP06915.1 - 0.0018 18.2 14.6 15 6.0 0.4 6.3 6 0 0 6 6 6 1 Leucine Rich repeat CDC24 PF06395.11 KFP06915.1 - 0.0094 16.2 0.0 0.023 14.9 0.0 1.7 1 0 0 1 1 1 1 CDC24 Calponin PUB_1 PF18486.1 KFP06915.1 - 0.019 14.8 1.4 0.042 13.7 1.4 1.5 1 0 0 1 1 1 0 PNGase/UBA- or UBX-containing domain CAMSAP_CH PF11971.8 KFP06915.1 - 0.036 13.9 0.1 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 CAMSAP CH domain LRR_9 PF14580.6 KFP06915.1 - 0.44 10.0 6.8 3.2 7.2 2.4 2.8 1 1 1 2 2 2 0 Leucine-rich repeat DUF4763 PF15960.5 KFP06915.1 - 8.5 5.6 19.6 0.8 9.0 12.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4763) IL6Ra-bind PF09240.10 KFP06916.1 - 3.1e-22 78.8 0.1 1e-21 77.2 0.0 2.0 2 0 0 2 2 2 1 Interleukin-6 receptor alpha chain, binding fn3 PF00041.21 KFP06916.1 - 1.5e-09 38.0 0.2 0.0018 18.6 0.1 3.2 3 0 0 3 3 3 2 Fibronectin type III domain EpoR_lig-bind PF09067.10 KFP06916.1 - 0.00048 20.3 0.1 0.0012 19.0 0.1 1.6 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding Il13Ra_Ig PF18001.1 KFP06916.1 - 0.012 15.7 1.3 4.8 7.4 0.0 3.2 3 1 0 3 3 3 0 Interleukin-13 receptor subunit alpha Ig-like domain Tissue_fac PF01108.17 KFP06916.1 - 0.091 12.6 4.1 5.2 7.0 0.1 3.6 2 1 2 4 4 4 0 Tissue factor 7tm_1 PF00001.21 KFP06917.1 - 3.3e-65 220.0 13.3 4.6e-65 219.6 13.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP06917.1 - 9.3e-13 48.1 14.3 2.4e-12 46.8 14.3 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP06917.1 - 1e-05 25.4 4.2 1e-05 25.4 4.2 2.4 2 1 1 3 3 3 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP06917.1 - 1.1e-05 25.2 12.2 1.1e-05 25.2 12.2 2.2 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Pox_P21 PF05313.12 KFP06917.1 - 0.041 13.4 0.6 0.041 13.4 0.6 3.0 3 0 0 3 3 3 0 Poxvirus P21 membrane protein RseC_MucC PF04246.12 KFP06917.1 - 3.5 7.6 7.0 0.26 11.2 0.3 2.4 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC GDPD PF03009.17 KFP06918.1 - 4.7e-20 72.4 0.1 1.4e-19 70.9 0.0 1.7 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family DUF2976 PF11190.8 KFP06918.1 - 4.2 7.2 9.5 9.8 6.1 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) SPO22 PF08631.10 KFP06919.1 - 2.9e-79 266.4 24.3 4.5e-75 252.7 4.8 3.3 3 0 0 3 3 3 3 Meiosis protein SPO22/ZIP4 like TPR_2 PF07719.17 KFP06919.1 - 1.2e-07 31.3 7.5 0.011 15.8 0.1 6.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFP06919.1 - 3.4e-07 30.4 3.8 0.022 15.0 0.4 5.4 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFP06919.1 - 0.00042 20.0 10.0 0.05 13.4 0.1 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP06919.1 - 0.0067 16.9 0.0 0.0067 16.9 0.0 4.7 7 1 0 7 7 7 1 Tetratricopeptide repeat DUF493 PF04359.14 KFP06919.1 - 0.0088 16.6 0.1 0.032 14.8 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF493) DUF4717 PF15838.5 KFP06919.1 - 0.015 15.3 0.2 0.053 13.5 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4717) ptaRNA1_toxin PF12703.7 KFP06919.1 - 0.096 12.7 0.1 0.29 11.2 0.1 1.8 1 0 0 1 1 1 0 Toxin of toxin-antitoxin type 1 system TPR_8 PF13181.6 KFP06919.1 - 0.11 12.8 4.4 0.41 11.0 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFP06919.1 - 0.47 11.4 2.4 28 5.9 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat MIT PF04212.18 KFP06919.1 - 0.63 10.1 3.8 1.5 8.9 0.1 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain RRM_1 PF00076.22 KFP06920.1 - 1.5e-18 66.4 0.0 1.9e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP06920.1 - 0.037 13.9 0.0 0.093 12.6 0.0 1.6 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_5 PF13893.6 KFP06920.1 - 0.16 11.6 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AA_permease_2 PF13520.6 KFP06921.1 - 8.8e-50 169.8 21.7 8.8e-50 169.8 21.7 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 KFP06921.1 - 2.5e-34 118.7 25.5 2.5e-34 118.7 25.5 2.4 2 1 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 KFP06921.1 - 3.2e-23 81.5 7.3 3.2e-23 81.5 7.3 4.3 4 0 0 4 4 4 1 C-terminus of AA_permease DUF1686 PF07937.11 KFP06921.1 - 0.14 12.0 5.6 0.052 13.4 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1686) PX PF00787.24 KFP06922.1 - 7.7e-22 77.4 0.2 8.5e-22 77.3 0.2 1.1 1 0 0 1 1 1 1 PX domain RdRP_1 PF00680.20 KFP06922.1 - 0.12 10.8 0.0 0.13 10.8 0.0 1.0 1 0 0 1 1 1 0 RNA dependent RNA polymerase PA26 PF04636.13 KFP06923.1 - 4e-180 599.5 0.1 4.5e-180 599.3 0.1 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) CMD PF02627.20 KFP06923.1 - 0.002 18.1 0.0 0.0058 16.7 0.0 1.8 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Leptin PF02024.15 KFP06923.1 - 0.018 14.8 0.0 0.29 10.9 0.0 2.3 2 0 0 2 2 2 0 Leptin IL6Ra-bind PF09240.10 KFP06924.1 - 1.2e-18 67.3 0.0 2.2e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.10 KFP06924.1 - 6.4e-08 32.7 0.1 1.4e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding fn3 PF00041.21 KFP06924.1 - 3.2e-06 27.4 0.6 3.2e-06 27.4 0.6 2.2 3 0 0 3 3 3 1 Fibronectin type III domain COesterase PF00135.28 KFP06925.1 - 2.7e-194 646.8 0.0 3.2e-194 646.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFP06925.1 - 4.8e-05 23.3 0.2 0.0003 20.7 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Connexin PF00029.19 KFP06926.1 - 4.4e-85 285.2 16.6 1.5e-83 280.1 16.6 2.0 1 1 0 1 1 1 1 Connexin Ninjurin PF04923.12 KFP06926.1 - 0.1 12.5 1.2 0.35 10.8 0.0 2.4 2 1 1 3 3 3 0 Ninjurin RRM_1 PF00076.22 KFP06927.1 - 1.8e-29 101.3 0.0 1.9e-13 50.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.11 KFP06927.1 - 4.8e-27 93.9 2.0 1.2e-26 92.6 2.0 1.7 1 0 0 1 1 1 1 NOPS (NUC059) domain RRM_7 PF16367.5 KFP06927.1 - 7.8e-05 22.7 0.0 0.0013 18.8 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif Lipoprotein_18 PF06804.11 KFP06927.1 - 0.52 9.3 8.2 0.059 12.4 3.5 1.7 1 1 1 2 2 2 0 NlpB/DapX lipoprotein Aldedh PF00171.22 KFP06927.1 - 3.5 6.0 5.2 4.7 5.6 5.2 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family GvpL_GvpF PF06386.11 KFP06927.1 - 4.8 7.0 15.8 7.2 6.5 15.8 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF3523 PF12037.8 KFP06927.1 - 5.5 6.3 28.0 8.3 5.7 28.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Totivirus_coat PF05518.11 KFP06927.1 - 7.6 4.4 8.4 9.6 4.1 8.4 1.1 1 0 0 1 1 1 0 Totivirus coat protein CHORD PF04968.12 KFP06928.1 - 7.8e-55 183.5 21.0 2e-28 98.9 6.7 3.2 3 0 0 3 3 3 2 CHORD CS PF04969.16 KFP06928.1 - 3.5e-12 47.2 0.3 5.7e-12 46.5 0.3 1.3 1 0 0 1 1 1 1 CS domain zf-tcix PF14952.6 KFP06928.1 - 0.0031 17.1 1.4 0.59 9.8 0.2 2.9 2 0 0 2 2 2 2 Putative treble-clef, zinc-finger, Zn-binding BTK PF00779.19 KFP06928.1 - 0.42 10.5 16.1 0.33 10.8 0.4 3.8 4 1 0 4 4 4 0 BTK motif Ras PF00071.22 KFP06929.1 - 2.1e-56 190.0 0.0 2.5e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP06929.1 - 2.1e-23 82.8 0.0 2.9e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP06929.1 - 7.3e-10 38.6 0.0 9.6e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP06929.1 - 0.0072 15.9 0.0 0.04 13.5 0.0 1.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 KFP06929.1 - 0.097 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF3591 PF12157.8 KFP06930.1 - 1.6e-163 544.5 0.6 5.9e-163 542.6 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 KFP06930.1 - 8.4e-45 150.8 3.8 5.5e-23 80.9 0.8 2.7 2 0 0 2 2 2 2 Bromodomain TBP-binding PF09247.11 KFP06930.1 - 2.6e-22 78.8 1.9 7.5e-22 77.4 1.9 1.8 1 0 0 1 1 1 1 TATA box-binding protein binding zf-CCHC_6 PF15288.6 KFP06930.1 - 3.7e-16 58.7 0.4 1.4e-15 56.9 0.4 2.0 1 0 0 1 1 1 1 Zinc knuckle Glyco_transf_41 PF13844.6 KFP06931.1 - 2.6e-256 850.4 0.0 3.4e-256 850.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 41 TPR_1 PF00515.28 KFP06931.1 - 6.7e-98 316.9 27.2 2.5e-10 39.7 0.3 13.5 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_11 PF13414.6 KFP06931.1 - 3.2e-90 295.6 36.3 9.1e-11 41.3 0.4 12.8 3 2 10 13 13 13 12 TPR repeat TPR_2 PF07719.17 KFP06931.1 - 6.4e-74 238.2 27.7 2.5e-08 33.4 0.4 13.2 13 0 0 13 13 12 11 Tetratricopeptide repeat TPR_17 PF13431.6 KFP06931.1 - 3.1e-68 221.4 28.8 1.9e-05 24.7 0.1 13.7 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_8 PF13181.6 KFP06931.1 - 1e-66 215.6 12.4 1.1e-06 28.4 0.1 13.6 14 0 0 14 14 13 11 Tetratricopeptide repeat TPR_12 PF13424.6 KFP06931.1 - 3.6e-48 161.7 29.2 2.8e-10 40.3 0.2 9.5 6 2 3 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.6 KFP06931.1 - 2e-46 152.7 17.0 0.00033 21.2 0.1 12.2 5 3 7 12 12 12 10 Tetratricopeptide repeat TPR_16 PF13432.6 KFP06931.1 - 1.5e-45 153.5 17.4 2.1e-09 37.9 0.1 7.6 6 1 0 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.6 KFP06931.1 - 1.3e-43 147.3 20.5 2e-07 31.4 0.6 9.2 4 4 5 9 9 9 9 Tetratricopeptide repeat TPR_7 PF13176.6 KFP06931.1 - 2.7e-39 130.3 17.3 9.7e-05 22.1 0.1 13.0 13 1 1 14 14 13 9 Tetratricopeptide repeat TPR_10 PF13374.6 KFP06931.1 - 5.3e-36 121.5 47.3 6.9e-07 28.9 0.4 12.2 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_9 PF13371.6 KFP06931.1 - 9.9e-18 64.1 14.7 0.00079 19.5 0.4 6.8 5 1 1 7 7 6 5 Tetratricopeptide repeat TPR_6 PF13174.6 KFP06931.1 - 2e-15 56.3 14.6 0.47 11.2 0.0 10.4 11 0 0 11 11 9 2 Tetratricopeptide repeat NARP1 PF12569.8 KFP06931.1 - 1.4e-14 53.9 4.9 0.0013 17.7 0.0 5.7 1 1 5 6 6 6 3 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 KFP06931.1 - 5.9e-14 51.2 9.7 1.4 9.7 0.2 9.3 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP06931.1 - 2.4e-12 46.9 12.7 0.00029 20.3 0.1 4.8 1 1 2 4 4 4 4 MalT-like TPR region TPR_15 PF13429.6 KFP06931.1 - 3.5e-10 39.6 8.0 4.7e-06 26.0 0.8 4.9 1 1 3 5 5 5 2 Tetratricopeptide repeat FAT PF02259.23 KFP06931.1 - 5.1e-08 32.5 0.1 0.88 8.7 0.0 5.7 2 2 1 4 4 4 2 FAT domain MIT PF04212.18 KFP06931.1 - 5.1e-07 29.7 22.0 0.11 12.6 0.1 8.5 7 1 2 9 9 8 2 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 KFP06931.1 - 2.5e-06 27.3 1.5 1.2 9.2 0.0 5.8 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_21 PF09976.9 KFP06931.1 - 7.6e-06 25.8 10.8 0.17 11.6 0.0 5.2 3 2 2 5 5 5 3 Tetratricopeptide repeat-like domain Wzy_C_2 PF11846.8 KFP06931.1 - 7.8e-05 22.7 12.3 0.0083 16.1 0.2 4.6 5 0 0 5 5 4 1 Virulence factor membrane-bound polymerase, C-terminal SNAP PF14938.6 KFP06931.1 - 0.00017 21.1 15.0 0.034 13.6 2.4 4.7 1 1 2 4 4 4 2 Soluble NSF attachment protein, SNAP EST1_DNA_bind PF10373.9 KFP06931.1 - 0.00017 21.1 13.9 0.23 10.9 0.1 4.8 5 1 1 6 6 6 2 Est1 DNA/RNA binding domain SHNi-TPR PF10516.9 KFP06931.1 - 0.0014 18.0 2.5 12 5.4 0.0 5.6 7 0 0 7 7 6 0 SHNi-TPR BTAD PF03704.17 KFP06931.1 - 0.002 18.6 16.4 0.31 11.4 0.7 5.7 3 2 4 7 7 7 1 Bacterial transcriptional activator domain ANAPC3 PF12895.7 KFP06931.1 - 0.011 15.9 16.5 0.056 13.7 0.9 5.5 3 2 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 KFP06931.1 - 0.018 14.7 6.9 29 4.3 0.1 6.1 4 2 5 9 9 9 0 26S proteasome subunit RPN7 TOM20_plant PF06552.12 KFP06931.1 - 0.048 13.4 0.3 30 4.3 0.0 4.0 3 2 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 Fis1_TPR_C PF14853.6 KFP06931.1 - 0.07 13.2 0.5 1 9.5 0.0 3.3 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat Tcf25 PF04910.14 KFP06931.1 - 0.081 12.0 0.1 0.22 10.6 0.0 1.7 2 0 0 2 2 2 0 Transcriptional repressor TCF25 Mad3_BUB1_I PF08311.12 KFP06931.1 - 0.16 11.9 9.0 91 3.1 0.1 6.8 6 1 1 8 8 8 0 Mad3/BUB1 homology region 1 DUF627 PF04781.12 KFP06931.1 - 0.19 11.8 3.9 6 6.9 0.0 4.5 3 1 2 5 5 4 0 Protein of unknown function (DUF627) TPR_20 PF14561.6 KFP06931.1 - 0.37 11.2 12.9 1.9 8.9 0.2 5.9 4 2 3 7 7 7 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KFP06931.1 - 1.4 9.4 3.9 12 6.3 0.1 3.3 4 0 0 4 4 2 0 Alkyl sulfatase dimerisation DUF5113 PF17140.4 KFP06931.1 - 1.6 8.5 11.3 26 4.6 0.2 5.5 3 2 4 7 7 7 0 Domain of unknown function (DUF5113) SprT-like PF10263.9 KFP06932.1 - 3.3e-15 55.9 0.0 5.9e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 SprT-like family TCL1_MTCP1 PF01840.17 KFP06933.1 - 1.2e-16 60.4 0.1 1.2e-16 60.4 0.1 1.0 1 0 0 1 1 1 1 TCL1/MTCP1 family MTCP1 PF08991.10 KFP06934.1 - 3.4e-10 40.0 6.1 3.6e-10 39.9 6.1 1.0 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type FUN14 PF04930.15 KFP06935.1 - 4.4e-26 91.1 3.7 5.7e-26 90.8 3.7 1.1 1 0 0 1 1 1 1 FUN14 family SH3BGR PF04908.15 KFP06935.1 - 0.051 13.7 0.0 8.4 6.6 0.0 2.2 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein SPC12 PF06645.13 KFP06935.1 - 0.28 11.3 2.2 0.25 11.5 0.3 1.9 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Guanylate_kin PF00625.21 KFP06936.1 - 1.2e-59 201.0 0.1 2.4e-59 200.1 0.1 1.5 1 0 0 1 1 1 1 Guanylate kinase PDZ PF00595.24 KFP06936.1 - 4.1e-19 68.7 2.7 4.4e-19 68.6 1.1 1.9 2 0 0 2 2 2 1 PDZ domain SH3_2 PF07653.17 KFP06936.1 - 2.9e-10 39.7 0.0 8e-10 38.3 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP06936.1 - 8e-09 35.0 1.1 4.4e-08 32.6 1.1 2.2 1 1 0 1 1 1 1 SH3 domain PDZ_6 PF17820.1 KFP06936.1 - 3.1e-06 26.9 0.2 1.1e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 PDZ domain SH3_9 PF14604.6 KFP06936.1 - 1.1e-05 25.1 0.0 2.8e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PDZ_2 PF13180.6 KFP06936.1 - 0.00014 22.1 0.2 0.0011 19.2 0.1 2.2 2 0 0 2 2 2 1 PDZ domain RsgA_GTPase PF03193.16 KFP06936.1 - 0.002 18.1 0.0 0.0071 16.3 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase Tricorn_PDZ PF14685.6 KFP06936.1 - 0.0026 17.7 0.4 0.51 10.3 0.1 3.3 3 1 0 3 3 3 1 Tricorn protease PDZ domain AAA_7 PF12775.7 KFP06936.1 - 0.03 13.8 0.0 0.072 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KFP06936.1 - 0.04 14.0 0.0 0.081 13.0 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase PDZ_4 PF17816.1 KFP06936.1 - 0.06 13.7 0.2 0.22 11.9 0.0 2.0 2 0 0 2 2 2 0 PDZ domain DKCLD PF08068.12 KFP06937.1 - 1.1e-24 86.2 0.2 5.9e-24 83.9 0.1 2.2 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 KFP06937.1 - 1.5e-22 79.5 0.3 2.7e-22 78.7 0.3 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 KFP06937.1 - 1.8e-22 80.3 0.1 2e-19 70.4 0.1 3.1 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 KFP06937.1 - 5.2e-18 64.8 1.0 8.8e-18 64.0 1.0 1.4 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KFP06937.1 - 0.0021 18.3 0.0 0.0053 17.0 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain tRNA_U5-meth_tr PF05958.11 KFP06938.1 - 4.6e-12 45.6 0.1 1.1e-10 41.0 0.1 2.3 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 KFP06938.1 - 3.5e-11 43.1 0.0 5.7e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP06938.1 - 7.5e-08 33.0 0.0 1.9e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFP06938.1 - 9e-06 25.3 0.0 1.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KFP06938.1 - 9.9e-05 21.9 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.12 KFP06938.1 - 0.0064 17.1 0.0 0.016 15.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 KFP06938.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 KFP06938.1 - 0.014 15.4 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KFP06938.1 - 0.025 14.4 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KFP06938.1 - 0.026 13.9 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NodS PF05401.11 KFP06938.1 - 0.08 12.5 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) PrmA PF06325.13 KFP06938.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 KFP06938.1 - 0.16 12.8 0.0 0.31 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DoxX_2 PF13564.6 KFP06939.1 - 2.9e-07 30.5 1.5 4.6e-07 29.9 1.5 1.3 1 0 0 1 1 1 1 DoxX-like family DUF4131 PF13567.6 KFP06939.1 - 0.0064 16.1 0.5 0.18 11.5 0.2 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4131) SID-1_RNA_chan PF13965.6 KFP06939.1 - 0.044 12.2 0.8 0.057 11.8 0.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 HCV_NS2 PF01538.18 KFP06939.1 - 0.1 12.2 1.2 0.14 11.8 1.2 1.2 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS2 Ac76 PF05814.11 KFP06939.1 - 0.12 12.4 2.6 0.14 12.2 0.8 1.9 2 0 0 2 2 2 0 Orf76 (Ac76) Sigma_reg_N PF13800.6 KFP06939.1 - 0.19 12.0 0.1 0.19 12.0 0.1 1.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF308 PF03729.13 KFP06939.1 - 0.87 10.0 0.0 0.87 10.0 0.0 3.2 3 1 0 3 3 3 0 Short repeat of unknown function (DUF308) CENP-I PF07778.11 KFP06940.1 - 4.8e-270 896.6 16.4 6.6e-270 896.1 16.4 1.1 1 0 0 1 1 1 1 Mis6 CBM46 PF18448.1 KFP06940.1 - 0.086 13.2 0.0 2 8.8 0.0 2.6 2 0 0 2 2 2 0 Carbohydrate binding domain TPR_2 PF07719.17 KFP06941.1 - 1.6e-05 24.7 4.9 0.032 14.3 0.4 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFP06941.1 - 0.016 14.9 2.8 1.8 8.3 0.2 2.7 3 0 0 3 3 3 0 TPR repeat TetR_C_24 PF17932.1 KFP06941.1 - 0.17 12.2 2.3 0.2 11.9 0.6 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TAFII55_N PF04658.13 KFP06942.1 - 1e-62 210.6 0.7 1e-62 210.6 0.7 2.3 2 0 0 2 2 2 1 TAFII55 protein conserved region LMBR1 PF04791.16 KFP06942.1 - 7.9 5.3 8.1 8.4 5.2 8.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Tweety PF04906.13 KFP06942.1 - 8.8 4.9 6.3 4.8 5.7 4.1 1.4 1 1 0 1 1 1 0 Tweety CHIP_TPR_N PF18391.1 KFP06942.1 - 9.2 7.1 26.3 6.8 7.5 1.8 3.9 2 1 1 3 3 3 0 CHIP N-terminal tetratricopeptide repeat domain zf-Tim10_DDP PF02953.15 KFP06943.1 - 9.3e-13 47.6 0.1 1.3e-12 47.2 0.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Pkinase_Tyr PF07714.17 KFP06944.1 - 2.5e-92 308.8 0.0 3.6e-92 308.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP06944.1 - 1.8e-46 158.6 0.0 2.7e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFP06944.1 - 2e-23 82.2 0.1 4.3e-23 81.2 0.1 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFP06944.1 - 3.8e-12 45.6 0.0 7.8e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain BTK PF00779.19 KFP06944.1 - 1.5e-08 34.3 2.8 3.4e-08 33.2 2.8 1.6 1 0 0 1 1 1 1 BTK motif SH3_9 PF14604.6 KFP06944.1 - 4.1e-06 26.6 0.0 9.7e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFP06944.1 - 0.0004 20.6 0.0 0.0013 19.0 0.0 1.9 2 0 0 2 2 1 1 Bacterial SH3 domain SH3_2 PF07653.17 KFP06944.1 - 0.00068 19.3 0.0 0.0018 17.9 0.0 1.8 1 1 0 1 1 1 1 Variant SH3 domain Kinase-like PF14531.6 KFP06944.1 - 0.0018 17.6 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFP06944.1 - 0.0088 15.0 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFP06944.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP06944.1 - 0.022 14.7 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFP06944.1 - 0.023 13.5 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SH3_4 PF06347.13 KFP06944.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Cas6b_N PF17955.1 KFP06944.1 - 0.091 12.8 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 Cas6b N-terminal domain SH3_10 PF17902.1 KFP06944.1 - 0.15 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 SH3 domain Ribosomal_L44 PF00935.19 KFP06945.1 - 1.5e-38 131.1 9.9 1.5e-38 131.1 9.9 1.7 1 1 1 2 2 2 1 Ribosomal protein L44 Neur_chan_LBD PF02931.23 KFP06946.1 - 1.1e-51 175.3 0.1 1.4e-51 175.0 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP06946.1 - 5.4e-39 134.7 0.3 9.3e-34 117.5 0.1 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Ras PF00071.22 KFP06947.1 - 3.1e-56 189.4 0.0 4.1e-56 189.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP06947.1 - 2.2e-30 105.3 0.0 3.4e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP06947.1 - 8.5e-10 38.4 0.0 9.4e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP06947.1 - 2.8e-06 27.4 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFP06947.1 - 1.3e-05 24.7 0.0 2.1e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KFP06947.1 - 1.6e-05 24.9 0.1 0.012 15.5 0.1 2.5 2 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFP06947.1 - 0.00013 21.6 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 KFP06947.1 - 0.0064 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 KFP06947.1 - 0.041 14.3 0.0 0.054 13.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 KFP06947.1 - 0.11 11.6 1.6 2.5 7.2 0.1 2.6 1 1 1 2 2 2 0 G-protein alpha subunit FeoB_N PF02421.18 KFP06947.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Thymosin PF01290.20 KFP06948.1 - 1.5e-19 69.4 13.6 1.9e-19 69.1 13.6 1.0 1 0 0 1 1 1 1 Thymosin beta-4 family DUF4522 PF15022.6 KFP06948.1 - 0.019 15.2 0.3 0.02 15.1 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4522) Pribosyl_synth PF14572.6 KFP06949.1 - 1.3e-44 152.5 2.4 9.7e-38 130.0 1.0 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KFP06949.1 - 4.6e-34 116.8 0.3 2.1e-33 114.7 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KFP06949.1 - 9.9e-14 51.2 0.9 1.5e-13 50.6 0.3 1.5 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KFP06949.1 - 0.00077 19.0 0.1 0.0012 18.3 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase FERM_N PF09379.10 KFP06950.1 - 0.0001 22.2 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 FERM N-terminal domain FERM_f0 PF16511.5 KFP06950.1 - 0.01 16.1 0.0 0.014 15.7 0.0 1.2 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM PIH1_CS PF18201.1 KFP06951.1 - 3.9e-11 43.2 0.0 4.7e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 PIH1 CS-like domain Nsp1_C PF05064.13 KFP06952.1 - 4.1e-39 133.0 8.3 4.1e-39 133.0 8.3 1.8 2 0 0 2 2 2 1 Nsp1-like C-terminal region DUF4164 PF13747.6 KFP06952.1 - 0.016 15.4 1.4 0.016 15.4 1.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Nup188_C PF18378.1 KFP06952.1 - 0.056 12.3 2.5 0.083 11.7 2.5 1.2 1 0 0 1 1 1 0 Nuclear pore protein NUP188 C-terminal domain GAS PF13851.6 KFP06952.1 - 0.17 11.2 14.7 0.33 10.3 14.7 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TBCC_N PF16752.5 KFP06952.1 - 1.9 9.0 8.0 0.63 10.5 0.7 2.4 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Laminin_II PF06009.12 KFP06952.1 - 3.1 7.8 9.7 3.4 7.7 1.2 2.3 1 1 1 2 2 2 0 Laminin Domain II FapA PF03961.13 KFP06952.1 - 3.4 6.2 7.4 2.8 6.5 2.6 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF16 PF01519.16 KFP06952.1 - 5.1 7.7 15.3 0.33 11.5 4.5 2.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 YscO-like PF16789.5 KFP06952.1 - 5.2 7.1 12.2 0.19 11.8 1.0 2.4 2 1 0 2 2 2 0 YscO-like protein DUF1664 PF07889.12 KFP06952.1 - 6.3 6.9 11.8 4.1 7.5 3.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) RRM_1 PF00076.22 KFP06953.1 - 1.3e-08 34.6 0.0 3e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PMP22_Claudin PF00822.20 KFP06954.1 - 5.2e-25 88.2 6.5 6.3e-25 88.0 6.5 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP06954.1 - 4.6e-07 29.8 8.0 1.1e-06 28.5 7.8 1.8 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.11 KFP06954.1 - 0.0018 18.1 3.7 0.0031 17.4 3.6 1.5 1 1 0 1 1 1 1 Amastin surface glycoprotein DuoxA PF10204.9 KFP06954.1 - 0.13 11.2 1.2 0.17 10.9 0.6 1.5 1 1 0 1 1 1 0 Dual oxidase maturation factor ATP-synt_I PF03899.15 KFP06954.1 - 0.7 10.3 6.8 0.065 13.6 1.1 2.1 2 0 0 2 2 2 0 ATP synthase I chain DUF872 PF05915.12 KFP06954.1 - 5.9 7.1 6.5 0.64 10.2 0.6 2.3 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Ion_trans PF00520.31 KFP06955.1 - 6.7e-30 104.1 8.1 1.2e-29 103.3 8.1 1.4 1 0 0 1 1 1 1 Ion transport protein CLZ PF16526.5 KFP06955.1 - 6.2e-23 80.9 4.8 1.8e-22 79.4 4.8 1.9 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels cNMP_binding PF00027.29 KFP06955.1 - 1e-17 63.9 0.0 1.9e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KFP06955.1 - 0.046 13.7 7.1 0.16 11.9 7.1 2.0 1 1 0 1 1 1 0 Ion channel Neur_chan_LBD PF02931.23 KFP06956.1 - 1.1e-36 126.3 1.6 1.4e-36 125.9 1.6 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP06956.1 - 3.9e-35 122.0 11.8 1.9e-31 110.0 7.0 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFP06957.1 - 9.1e-48 162.5 0.0 1.4e-47 162.0 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP06957.1 - 1.3e-38 133.4 7.5 2.3e-31 109.7 5.9 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_memb PF02932.16 KFP06958.1 - 1.5e-52 179.0 0.0 2.5e-52 178.3 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFP06958.1 - 1.3e-36 126.1 0.1 1.8e-36 125.6 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain SOXp PF12336.8 KFP06959.1 - 6.4e-34 116.9 2.6 6.4e-34 116.9 2.6 2.9 3 0 0 3 3 3 1 SOX transcription factor HMG_box PF00505.19 KFP06959.1 - 1.6e-27 95.7 3.4 2.4e-27 95.1 2.4 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP06959.1 - 1.8e-11 44.4 2.0 3e-11 43.7 2.0 1.4 1 0 0 1 1 1 1 HMG-box domain Host_attach PF10116.9 KFP06960.1 - 0.00063 20.3 23.8 1.1e+04 -3.1 23.8 4.2 1 1 0 1 1 1 0 Protein required for attachment to host cells Minor_tail_Z PF06763.11 KFP06960.1 - 0.0028 17.5 49.4 1.8e+04 -26.7 49.4 4.3 1 1 0 1 1 0 0 Prophage minor tail protein Z (GPZ) MgtE_N PF03448.17 KFP06960.1 - 0.02 15.5 29.5 71 4.1 29.5 2.4 1 1 0 1 1 1 0 MgtE intracellular N domain DUF4816 PF16086.5 KFP06960.1 - 0.042 13.8 26.9 1.8e+04 -13.4 26.9 4.6 1 1 0 1 1 0 0 Domain of unknown function (DUF4816) baeRF_family12 PF18856.1 KFP06960.1 - 0.23 12.0 34.9 1.8e+04 -7.4 34.9 4.6 1 1 0 1 1 0 0 Bacterial archaeo-eukaryotic release factor family 12 DUF2294 PF10057.9 KFP06960.1 - 0.33 11.1 45.9 1.8e+04 -27.9 45.9 5.2 1 1 0 1 1 0 0 Uncharacterized conserved protein (DUF2294) DUF445 PF04286.12 KFP06960.1 - 0.8 9.4 25.7 1.9 8.2 25.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF445) CdiI_2 PF18593.1 KFP06960.1 - 1 10.0 19.7 1.8e+04 -6.1 19.7 3.7 1 1 0 1 1 0 0 CdiI immunity protein DUF3313 PF11769.8 KFP06960.1 - 2 8.2 22.3 1.8e+04 -10.3 22.3 3.9 1 1 0 1 1 0 0 Protein of unknown function (DUF3313) WASH-7_mid PF14744.6 KFP06960.1 - 2.8 6.9 24.0 1.1e+03 -1.5 24.0 2.2 1 1 0 1 1 1 0 WASH complex subunit 7 Tam41_Mmp37 PF09139.11 KFP06960.1 - 3.8 6.8 26.9 2.7e+02 0.7 26.9 2.0 1 1 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial RHD3 PF05879.12 KFP06960.1 - 4.9 5.2 26.4 5.2 5.1 26.4 1.0 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) DUF1104 PF06518.11 KFP06960.1 - 5.7 7.4 75.0 1.8e+04 -29.0 75.0 3.0 1 1 0 1 1 0 0 Protein of unknown function (DUF1104) Aha1_N PF09229.11 KFP06960.1 - 5.8 7.1 24.5 1.8e+04 -11.3 24.5 4.0 1 1 0 1 1 0 0 Activator of Hsp90 ATPase, N-terminal Host_attach PF10116.9 KFP06961.1 - 3.4e-05 24.4 44.5 1.8e+04 -22.5 44.5 6.8 1 1 0 1 1 1 0 Protein required for attachment to host cells MgtE_N PF03448.17 KFP06961.1 - 0.00021 21.8 52.0 1.8e+04 -18.3 52.0 3.5 1 1 0 1 1 1 0 MgtE intracellular N domain Minor_tail_Z PF06763.11 KFP06961.1 - 0.00086 19.1 87.8 1.8e+04 -63.2 87.8 7.2 1 1 0 1 1 1 0 Prophage minor tail protein Z (GPZ) DUF4816 PF16086.5 KFP06961.1 - 0.15 12.0 50.6 1.8e+04 -37.2 50.6 7.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4816) DUF445 PF04286.12 KFP06961.1 - 0.69 9.7 49.1 1.9e+02 1.6 49.1 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) baeRF_family12 PF18856.1 KFP06961.1 - 0.91 10.1 63.0 1.8e+04 -34.6 63.0 7.4 1 1 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 RHD3 PF05879.12 KFP06961.1 - 1.6 6.8 49.2 1.8 6.6 49.2 1.0 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) DUF2294 PF10057.9 KFP06961.1 - 2.4 8.3 81.1 1.8e+04 -63.1 81.1 8.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) CdiI_2 PF18593.1 KFP06961.1 - 3.8 8.2 37.3 1.8e+04 -23.8 37.3 5.7 1 1 0 1 1 1 0 CdiI immunity protein LRR_8 PF13855.6 KFP06963.1 - 2e-50 168.4 39.1 6.7e-16 57.8 5.5 6.6 2 2 4 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 KFP06963.1 - 6.3e-23 80.5 45.4 8.4e-07 29.2 0.4 8.1 5 2 3 9 9 9 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP06963.1 - 2.5e-17 63.1 0.6 2.2e-08 34.1 0.9 2.5 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP06963.1 - 1e-08 34.9 15.9 0.00013 21.5 0.4 4.4 2 2 3 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.33 KFP06963.1 - 0.00022 21.3 39.1 0.19 12.4 0.0 10.7 10 2 0 10 10 10 2 Leucine Rich Repeat LRRNT PF01462.18 KFP06963.1 - 0.00044 19.8 3.3 0.00044 19.8 3.3 2.3 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain TPKR_C2 PF16920.5 KFP06963.1 - 0.0012 18.9 0.5 0.15 12.2 0.1 3.0 2 0 0 2 2 2 1 Tyrosine-protein kinase receptor C2 Ig-like domain OSTbeta PF15048.6 KFP06963.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein LRR_8 PF13855.6 KFP06964.1 - 1.8e-44 149.3 67.8 2.3e-16 59.3 1.7 6.7 2 2 5 7 7 7 7 Leucine rich repeat LRR_5 PF13306.6 KFP06964.1 - 5.7e-17 61.9 0.1 3.8e-07 30.1 0.0 2.3 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFP06964.1 - 4.1e-14 52.5 50.5 2.5e-05 24.5 0.8 8.0 6 1 3 9 9 9 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP06964.1 - 1.2e-05 25.1 36.5 2.7 8.9 0.3 10.9 10 2 0 10 10 10 4 Leucine Rich Repeat LRR_9 PF14580.6 KFP06964.1 - 0.0001 21.9 12.5 0.11 12.0 0.1 4.1 2 2 2 4 4 4 3 Leucine-rich repeat LRRNT PF01462.18 KFP06964.1 - 0.00024 20.7 1.5 0.00024 20.7 1.5 2.9 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain MCLC PF05934.11 KFP06964.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) RVT_1 PF00078.27 KFP06965.1 - 0.09 12.3 0.0 0.3 10.6 0.0 1.9 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Fe-ADH PF00465.19 KFP06966.1 - 2.1e-105 352.6 0.0 2.5e-105 352.3 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KFP06966.1 - 9.8e-15 54.9 0.0 1.8e-10 41.0 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Cmyb_C PF09316.10 KFP06968.1 - 4.1e-79 264.0 1.9 1e-78 262.7 1.9 1.7 1 0 0 1 1 1 1 C-myb, C-terminal Myb_DNA-binding PF00249.31 KFP06968.1 - 6.7e-52 173.5 17.3 4e-18 65.3 2.0 3.8 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFP06968.1 - 1.3e-39 134.2 18.1 4.8e-18 65.2 2.6 4.1 2 1 2 4 4 4 3 Myb-like DNA-binding domain LMSTEN PF07988.12 KFP06968.1 - 1.4e-25 88.5 0.3 2.9e-25 87.5 0.3 1.6 1 0 0 1 1 1 1 LMSTEN motif Myb_DNA-bind_7 PF15963.5 KFP06968.1 - 7.5e-08 32.2 5.2 0.00037 20.3 0.1 3.7 1 1 2 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 KFP06968.1 - 1e-05 25.5 5.6 1.2 9.1 0.2 4.3 2 1 2 4 4 4 3 SLIDE SANT_DAMP1_like PF16282.5 KFP06968.1 - 0.0014 18.8 3.8 1.5 9.1 0.0 3.8 1 1 2 3 3 3 1 SANT/Myb-like domain of DAMP1 Spore_III_AB PF09548.10 KFP06968.1 - 0.13 12.3 1.0 1.3 9.1 0.1 2.8 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Sigma70_r4_2 PF08281.12 KFP06968.1 - 0.14 11.9 0.0 0.67 9.7 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 Rap1_C PF11626.8 KFP06968.1 - 0.17 12.0 9.6 0.86 9.7 0.6 4.2 2 1 2 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DegQ PF08181.11 KFP06968.1 - 0.26 11.4 2.3 0.48 10.6 0.8 2.2 2 0 0 2 2 2 0 DegQ (SacQ) family OTU PF02338.19 KFP06969.1 - 4.7e-11 43.3 0.0 1.3e-10 41.9 0.0 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease ubiquitin PF00240.23 KFP06969.1 - 0.033 13.9 0.0 0.079 12.7 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family Mut7-C PF01927.16 KFP06969.1 - 0.15 12.1 0.1 3.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Mut7-C RNAse domain Zn-ribbon_8 PF09723.10 KFP06969.1 - 0.19 11.8 1.4 8.7 6.6 0.1 2.9 3 0 0 3 3 3 0 Zinc ribbon domain P120R PF08062.11 KFP06969.1 - 5.4 7.5 7.4 0.46 10.9 1.6 2.3 2 0 0 2 2 2 0 P120R (NUC006) repeat Pkinase PF00069.25 KFP06970.1 - 2.9e-67 226.8 0.0 3.4e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP06970.1 - 1.3e-34 119.7 0.0 1.5e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP06970.1 - 2.1e-05 24.0 0.1 7.6e-05 22.2 0.1 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 KFP06970.1 - 0.00075 20.2 0.1 0.0014 19.3 0.1 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain FTA2 PF13095.6 KFP06970.1 - 0.0013 18.5 0.1 0.24 11.0 0.1 2.1 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KFP06970.1 - 0.0062 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFP06970.1 - 0.066 12.1 0.0 0.095 11.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KFP06970.1 - 0.16 11.8 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family MCM_lid PF17855.1 KFP06971.1 - 1.7e-09 38.0 0.5 3.2e-09 37.1 0.5 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM PF00493.23 KFP06971.1 - 0.00049 19.3 0.0 0.00095 18.3 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain amfpi-1 PF12190.8 KFP06971.1 - 0.13 12.9 0.1 0.61 10.7 0.0 2.1 2 0 0 2 2 2 0 Fungal protease inhibitor LRR_4 PF12799.7 KFP06972.1 - 1.2e-18 66.9 24.2 7.2e-08 32.6 2.8 4.6 3 2 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP06972.1 - 1.1e-16 60.8 12.4 2e-09 37.2 2.1 3.0 2 1 0 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KFP06972.1 - 1.7e-14 53.3 18.0 0.00016 21.4 2.3 4.9 3 1 1 5 5 5 4 Leucine rich repeat LRR_1 PF00560.33 KFP06972.1 - 4.5e-08 32.6 18.5 1.2 9.9 0.1 7.5 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.6 KFP06972.1 - 0.016 15.2 13.3 34 4.9 0.2 7.0 7 0 0 7 7 7 0 Leucine Rich repeat FNIP PF05725.12 KFP06972.1 - 5 7.4 8.5 19 5.5 4.5 3.5 2 1 0 2 2 2 0 FNIP Repeat JAB PF01398.21 KFP06973.1 - 3.9e-34 117.1 0.0 6.1e-34 116.5 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 KFP06973.1 - 1.4e-24 86.8 0.6 2.3e-24 86.1 0.6 1.4 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 KFP06973.1 - 0.00013 21.8 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 KFP06973.1 - 0.0033 17.5 0.1 0.0067 16.5 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) Sec7 PF01369.20 KFP06974.1 - 2.5e-75 252.2 0.6 7e-75 250.7 0.6 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KFP06974.1 - 1.6e-49 167.8 3.4 1.6e-49 167.8 3.4 3.4 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KFP06974.1 - 2.8e-43 147.6 0.1 2.8e-43 147.6 0.1 3.5 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 KFP06974.1 - 8.5e-36 121.7 0.2 8.5e-36 121.7 0.2 4.9 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) Sec23_helical PF04815.15 KFP06974.1 - 0.21 11.5 1.7 16 5.3 0.0 3.2 3 0 0 3 3 3 0 Sec23/Sec24 helical domain Peptidase_M14 PF00246.24 KFP06975.1 - 8.1e-90 301.5 0.1 1e-89 301.2 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KFP06975.1 - 3.4e-15 56.2 0.2 7.8e-15 55.0 0.2 1.7 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Pkinase PF00069.25 KFP06976.1 - 1.8e-36 125.9 0.0 2.4e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP06976.1 - 8.2e-31 107.2 0.0 1.4e-30 106.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KFP06976.1 - 0.024 14.2 0.0 0.04 13.5 0.0 1.3 1 1 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KFP06976.1 - 0.11 11.2 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH_6_hur PF04655.14 KFP06976.1 - 0.18 11.2 0.1 0.86 8.9 0.0 1.9 1 1 1 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Acetyltransf_13 PF13880.6 KFP06977.1 - 5.4e-29 100.0 0.0 1.2e-28 98.8 0.0 1.6 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 KFP06977.1 - 1.1e-16 60.3 0.5 2.5e-16 59.2 0.5 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO NFACT-R_1 PF05670.13 KFP06978.1 - 5.1e-22 78.6 0.0 1.3e-20 74.1 0.0 2.0 1 1 0 1 1 1 1 NFACT protein RNA binding domain Lebercilin PF15619.6 KFP06979.1 - 9.8e-06 25.4 5.4 1.9e-05 24.4 1.2 2.9 1 1 1 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease DUF948 PF06103.11 KFP06979.1 - 0.0004 20.6 7.0 1.7 9.0 0.6 4.2 3 1 1 4 4 4 1 Bacterial protein of unknown function (DUF948) DUF2408 PF10303.9 KFP06979.1 - 0.0016 19.0 5.1 0.17 12.5 0.8 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2408) DUF2703 PF10865.8 KFP06979.1 - 0.0023 18.1 3.3 0.0079 16.4 0.7 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF2703) HrpB7 PF09486.10 KFP06979.1 - 0.0089 16.4 3.7 7.2 7.0 0.0 4.0 1 1 4 5 5 5 0 Bacterial type III secretion protein (HrpB7) DUF1664 PF07889.12 KFP06979.1 - 0.01 15.9 7.7 2.9 7.9 1.6 3.9 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 KFP06979.1 - 0.01 16.3 5.2 2.4 8.7 2.1 4.4 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein FAM184 PF15665.5 KFP06979.1 - 0.01 15.6 6.5 0.38 10.5 0.4 2.2 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B AAA_13 PF13166.6 KFP06979.1 - 0.012 14.3 2.3 0.019 13.6 0.9 1.8 1 1 0 1 1 1 0 AAA domain UPF0242 PF06785.11 KFP06979.1 - 0.018 15.2 7.5 0.54 10.3 1.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Phage_GP20 PF06810.11 KFP06979.1 - 0.018 14.8 0.5 0.4 10.5 1.1 2.4 2 1 1 3 3 3 0 Phage minor structural protein GP20 TPR_MLP1_2 PF07926.12 KFP06979.1 - 0.037 14.1 9.8 0.061 13.4 2.2 2.7 3 0 0 3 3 2 0 TPR/MLP1/MLP2-like protein TPD52 PF04201.15 KFP06979.1 - 0.047 13.3 1.4 0.39 10.3 0.7 2.4 2 1 0 2 2 2 0 Tumour protein D52 family DUF983 PF06170.12 KFP06979.1 - 0.053 13.9 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF983) DUF4200 PF13863.6 KFP06979.1 - 0.12 12.8 3.7 9.1 6.7 1.4 3.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) WEMBL PF05701.11 KFP06979.1 - 0.23 10.1 6.5 0.057 12.1 1.1 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light KASH_CCD PF14662.6 KFP06979.1 - 0.25 11.2 10.8 1.7 8.4 4.6 2.6 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH IFT57 PF10498.9 KFP06979.1 - 0.29 10.1 6.4 0.85 8.5 0.0 2.6 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 SPATA1_C PF15743.5 KFP06979.1 - 0.44 10.6 3.7 4.8 7.2 0.3 2.8 2 1 0 2 2 2 0 Spermatogenesis-associated C-terminus BORCS7 PF16088.5 KFP06979.1 - 0.74 10.1 8.1 0.28 11.5 1.6 2.9 2 2 0 2 2 2 0 BLOC-1-related complex sub-unit 7 Tropomyosin_1 PF12718.7 KFP06979.1 - 0.77 9.9 7.0 12 6.0 0.2 2.6 2 0 0 2 2 2 0 Tropomyosin like GAS PF13851.6 KFP06979.1 - 0.98 8.7 10.4 1.4 8.2 0.6 2.7 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding ABC_tran_CTD PF16326.5 KFP06979.1 - 1.3 9.4 7.1 1.5 9.1 0.9 3.4 3 1 1 4 4 4 0 ABC transporter C-terminal domain Serine_rich PF08824.10 KFP06979.1 - 1.3 9.0 8.7 0.34 10.9 2.4 2.5 1 1 1 2 2 2 0 Serine rich protein interaction domain Seryl_tRNA_N PF02403.22 KFP06979.1 - 1.4 9.2 4.6 7.6 6.8 0.5 3.4 2 2 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Rx_N PF18052.1 KFP06979.1 - 1.7 9.0 5.8 3.6 7.9 0.8 3.1 1 1 2 3 3 3 0 Rx N-terminal domain AI-2E_transport PF01594.16 KFP06979.1 - 2 7.5 6.7 1.1 8.3 2.4 2.4 2 1 0 2 2 2 0 AI-2E family transporter ATG16 PF08614.11 KFP06979.1 - 2.1 8.6 12.4 1.7 8.8 4.9 3.1 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Fmp27_WPPW PF10359.9 KFP06979.1 - 2.5 6.8 5.7 2.5 6.9 1.0 2.1 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain FlaC_arch PF05377.11 KFP06979.1 - 3.1 8.3 13.4 63 4.1 0.4 5.5 6 0 0 6 6 6 0 Flagella accessory protein C (FlaC) Cep57_CLD_2 PF14197.6 KFP06979.1 - 6 7.0 11.1 5.1 7.3 0.5 3.4 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 DUF3450 PF11932.8 KFP06979.1 - 7.5 5.8 11.7 11 5.2 3.3 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) CorA PF01544.18 KFP06979.1 - 9.8 5.4 15.8 0.99 8.7 0.7 3.1 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein Clusterin PF01093.17 KFP06980.1 - 3.6e-119 398.6 5.9 3.5e-101 339.4 3.9 2.1 2 0 0 2 2 2 2 Clusterin U1snRNP70_N PF12220.8 KFP06980.1 - 0.017 15.7 3.2 0.017 15.7 3.2 2.5 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal MRPL52 PF18699.1 KFP06980.1 - 8.5 6.6 10.8 19 5.5 0.0 2.3 2 0 0 2 2 2 0 Mitoribosomal protein mL52 EamA PF00892.20 KFP06981.1 - 2.8e-11 43.7 16.2 1.1e-06 28.9 1.1 2.6 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KFP06981.1 - 1.2e-08 34.7 0.6 1.6e-08 34.3 0.6 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family SLC35F PF06027.12 KFP06981.1 - 4.4e-08 33.0 3.0 3e-07 30.3 0.1 2.1 2 0 0 2 2 2 1 Solute carrier family 35 CRT-like PF08627.10 KFP06981.1 - 6.1e-05 22.1 6.7 0.00011 21.2 1.8 2.0 1 1 1 2 2 2 2 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 KFP06981.1 - 0.00011 21.5 0.1 0.00017 20.9 0.1 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter Ion_trans_2 PF07885.16 KFP06982.1 - 1e-39 134.3 15.8 8.9e-20 70.4 7.9 3.0 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KFP06982.1 - 5.9e-09 35.5 6.0 0.0012 18.2 0.0 2.2 2 0 0 2 2 2 2 Ion transport protein IRK PF01007.20 KFP06982.1 - 0.33 10.8 5.9 0.42 10.4 0.0 2.7 2 1 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain DUF2786 PF10979.8 KFP06982.1 - 0.89 9.5 5.7 3.3 7.7 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) 7tm_4 PF13853.6 KFP06984.1 - 1e-13 51.7 1.1 1.2e-13 51.5 1.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP06984.1 - 3.3e-08 33.2 0.5 4.2e-08 32.8 0.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CholecysA-Rec_N PF09193.10 KFP06984.1 - 0.078 13.0 0.1 0.14 12.2 0.1 1.5 1 1 0 1 1 1 0 Cholecystokinin A receptor, N-terminal Kelch_1 PF01344.25 KFP06985.1 - 3.1e-74 244.3 15.8 1.1e-15 56.9 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFP06985.1 - 7.6e-43 143.5 5.8 2.3e-08 34.0 0.0 6.3 3 2 3 6 6 6 6 Kelch motif Kelch_2 PF07646.15 KFP06985.1 - 3.2e-28 96.6 9.6 4.2e-05 23.3 0.0 6.3 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 KFP06985.1 - 6.3e-28 96.9 0.9 6.3e-28 96.9 0.9 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 KFP06985.1 - 4.6e-25 87.4 9.9 0.00014 22.0 0.1 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain BTB PF00651.31 KFP06985.1 - 1.2e-24 86.7 1.4 1.2e-24 86.7 1.4 1.8 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.6 KFP06985.1 - 8.3e-24 83.3 4.8 5.6e-05 23.1 0.0 6.3 4 2 2 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP06985.1 - 0.00058 19.8 12.0 2.2 8.4 0.0 5.4 6 0 0 6 6 6 3 Kelch motif AF-4 PF05110.13 KFP06986.1 - 0 1469.3 79.7 0 1469.1 79.7 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein BRD4_CDT PF17105.5 KFP06986.1 - 0.11 12.1 1.9 0.4 10.3 1.9 2.0 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 DUF4407 PF14362.6 KFP06986.1 - 3.3 7.0 6.1 6.3 6.0 6.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LicD PF04991.13 KFP06986.1 - 3.9 7.6 7.6 0.51 10.4 2.2 2.1 1 1 1 2 2 2 0 LicD family Y_phosphatase PF00102.27 KFP06987.1 - 5.7e-77 258.4 0.0 6.5e-77 258.3 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFP06987.1 - 0.0002 21.1 0.0 0.00033 20.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFP06987.1 - 0.0011 19.1 0.0 0.003 17.7 0.0 1.7 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KFP06987.1 - 0.19 11.7 0.0 0.37 10.7 0.0 1.3 1 1 0 1 1 1 0 Tyrosine phosphatase family RVT_1 PF00078.27 KFP06988.1 - 0.0003 20.4 0.0 0.00047 19.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) OSK PF17182.4 KFP06989.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 OSK domain Lipase_GDSL_2 PF13472.6 KFP06989.1 - 0.0025 18.2 0.0 0.0061 17.0 0.0 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF1192 PF06698.11 KFP06989.1 - 0.25 11.4 1.0 0.69 10.0 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Pkinase PF00069.25 KFP06990.1 - 4.7e-65 219.6 0.0 5.9e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP06990.1 - 5.8e-31 107.7 0.1 7.9e-31 107.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFP06990.1 - 2.1e-07 30.5 0.2 3.3e-07 29.9 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFP06990.1 - 5.8e-05 22.5 0.0 0.00012 21.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFP06990.1 - 0.00033 20.3 0.2 0.0006 19.5 0.2 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KFP06990.1 - 0.00064 19.7 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KFP06990.1 - 0.066 12.8 0.0 0.14 11.7 0.0 1.7 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KFP06990.1 - 0.096 11.6 0.7 0.22 10.4 0.7 1.6 1 1 0 1 1 1 0 Haspin like kinase domain RhoGAP PF00620.27 KFP06992.1 - 2.1e-48 164.0 0.8 3.9e-48 163.1 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 KFP06992.1 - 9.4e-17 61.5 2.5 1.1e-16 61.2 0.1 2.4 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 KFP06992.1 - 3e-08 34.0 0.1 3e-08 34.0 0.1 2.9 3 0 0 3 3 3 1 Pleckstrin homology domain ATG16 PF08614.11 KFP06992.1 - 0.0015 18.8 7.2 0.0015 18.8 7.2 2.7 3 0 0 3 3 3 1 Autophagy protein 16 (ATG16) ADIP PF11559.8 KFP06992.1 - 0.0097 16.0 6.5 0.0097 16.0 6.5 2.3 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding PH_9 PF15410.6 KFP06992.1 - 0.016 15.6 0.4 0.53 10.7 0.4 2.8 1 1 0 1 1 1 0 Pleckstrin homology domain DUF3435 PF11917.8 KFP06992.1 - 0.069 12.1 6.7 0.13 11.1 6.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) KLRAQ PF10205.9 KFP06992.1 - 1.8 8.8 15.9 1.2 9.4 8.4 3.2 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein bZIP_1 PF00170.21 KFP06992.1 - 1.8 8.7 16.2 2.1 8.5 5.4 3.9 2 1 2 4 4 4 0 bZIP transcription factor CSN4_RPN5_eIF3a PF18420.1 KFP06993.1 - 3.1e-25 88.0 3.7 8.3e-25 86.7 3.7 1.8 1 0 0 1 1 1 1 CSN4/RPN5/eIF3a helix turn helix domain PCI PF01399.27 KFP06993.1 - 4.4e-18 65.7 3.5 9.4e-18 64.7 0.0 2.8 3 1 0 3 3 3 1 PCI domain RPN7 PF10602.9 KFP06993.1 - 0.0038 17.0 1.1 0.0069 16.1 1.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_12 PF13424.6 KFP06993.1 - 0.015 15.6 1.1 0.9 9.9 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP06993.1 - 0.027 14.5 1.1 3.2 8.0 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFP06993.1 - 0.23 11.7 1.9 3 8.3 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat YabA PF06156.13 KFP06993.1 - 3.6 8.3 8.3 12 6.5 0.2 3.5 3 1 1 4 4 4 0 Initiation control protein YabA TCR PF03638.15 KFP06994.1 - 1.5e-22 79.6 59.0 8.9e-13 48.3 22.9 2.7 3 0 0 3 3 3 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 KFP06994.1 - 0.11 12.6 45.0 0.35 11.0 17.1 2.7 2 0 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 Sec16_C PF12931.7 KFP06995.1 - 1.9e-06 27.8 2.2 1.2e-05 25.1 2.2 2.2 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 SRA1 PF07304.11 KFP06995.1 - 0.00055 19.8 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.15 KFP06995.1 - 0.0031 17.5 0.4 0.011 15.8 0.0 1.9 2 0 0 2 2 2 1 Prp18 domain FA_desaturase PF00487.24 KFP06996.1 - 8.4e-18 65.1 11.6 1e-17 64.8 11.6 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Frag1 PF10277.9 KFP06997.1 - 8.2e-44 149.7 8.1 9.5e-44 149.5 8.1 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF1129 PF06570.11 KFP06997.1 - 0.043 13.3 0.7 0.043 13.3 0.7 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) Hydrolase PF00702.26 KFP06998.1 - 0.00077 19.8 0.0 0.00089 19.6 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFP06998.1 - 0.02 15.0 0.0 0.042 13.9 0.0 1.5 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase MLD PF11647.8 KFP06998.1 - 0.14 12.5 0.0 13 6.2 0.0 2.4 2 0 0 2 2 2 0 Membrane Localization Domain RRM_1 PF00076.22 KFP06999.1 - 1.8e-34 117.4 0.1 2.5e-16 59.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP06999.1 - 1.1e-18 67.1 0.1 8.4e-10 38.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KFP06999.1 - 8.7e-05 22.4 0.0 0.017 15.1 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KFP06999.1 - 0.00012 22.0 0.5 0.048 13.7 0.2 2.8 2 2 0 2 2 2 2 RNA binding motif RL PF17797.1 KFP06999.1 - 0.038 13.9 0.0 4.2 7.4 0.0 2.6 2 1 0 2 2 2 0 RL domain RRM_1 PF00076.22 KFP07000.1 - 3.4e-36 122.9 0.4 2.6e-17 62.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP07000.1 - 3.6e-18 65.5 1.1 1.7e-08 34.4 0.1 2.6 2 1 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 KFP07000.1 - 2.3e-07 30.8 0.6 0.0038 17.2 0.1 2.6 2 1 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.6 KFP07000.1 - 0.00029 20.8 0.0 0.034 14.1 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif NID PF07292.13 KFP07000.1 - 0.0004 21.0 0.5 0.012 16.2 0.0 2.5 2 1 0 2 2 2 1 Nmi/IFP 35 domain (NID) DUF2076 PF09849.9 KFP07000.1 - 2 8.4 6.0 2.9 7.9 6.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) HORMA PF02301.18 KFP07001.1 - 7.9e-23 81.2 0.3 1.2e-22 80.6 0.3 1.2 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 KFP07001.1 - 0.00012 22.0 0.6 0.0026 17.7 0.6 2.2 1 1 0 1 1 1 1 Autophagy-related protein 101 DUF4246 PF14033.6 KFP07001.1 - 0.035 13.2 0.1 0.042 13.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) DUF2791 PF10923.8 KFP07001.1 - 0.052 12.4 0.1 0.064 12.1 0.1 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Ribosomal_L30_N PF08079.12 KFP07002.1 - 2.3e-20 72.6 7.7 2.3e-20 72.6 7.7 1.9 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KFP07002.1 - 2.4e-14 52.9 2.2 2.4e-14 52.9 2.2 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e PDEase_I PF00233.19 KFP07003.1 - 1.3e-76 257.4 2.0 1.3e-76 257.4 2.0 2.3 2 1 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 KFP07003.1 - 1.3e-33 116.5 0.0 2.5e-15 57.3 0.0 2.5 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 KFP07003.1 - 3.7e-07 30.5 0.0 0.0035 17.6 0.0 2.6 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 KFP07003.1 - 8.9e-05 22.8 0.0 4.9 7.5 0.0 4.5 3 2 0 3 3 3 2 GAF domain UTP15_C PF09384.10 KFP07003.1 - 0.038 13.7 0.5 0.42 10.3 0.1 2.6 2 0 0 2 2 2 0 UTP15 C terminal ATLF PF07737.11 KFP07003.1 - 0.088 12.1 2.0 0.2 10.9 1.3 2.0 2 0 0 2 2 2 0 Anthrax toxin lethal factor, N- and C-terminal domain zf_ZIC PF18366.1 KFP07003.1 - 0.3 11.2 2.7 40 4.4 0.2 3.6 3 1 1 4 4 4 0 Zic proteins zinc finger domain UCH PF00443.29 KFP07004.1 - 9.8e-20 71.1 3.0 1.3e-19 70.7 0.2 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP07004.1 - 4.7e-08 33.0 4.3 4.7e-08 33.0 4.3 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Calsarcin PF05556.11 KFP07005.1 - 2.8e-78 263.0 0.3 8.2e-78 261.5 0.3 1.6 1 1 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) PDZ_6 PF17820.1 KFP07006.1 - 1.9e-06 27.6 0.0 4e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFP07006.1 - 0.0011 19.3 0.0 0.0024 18.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP07006.1 - 0.024 15.0 0.0 0.076 13.4 0.0 1.9 2 0 0 2 2 2 0 PDZ domain Sec23_trunk PF04811.15 KFP07007.1 - 2.2e-82 276.3 0.1 3.7e-82 275.6 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KFP07007.1 - 1.9e-23 82.2 0.1 3.7e-23 81.3 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KFP07007.1 - 1.9e-17 63.8 1.6 2.9e-17 63.2 0.0 2.2 3 0 0 3 3 3 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KFP07007.1 - 5.2e-13 48.8 9.7 1.4e-12 47.5 9.7 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KFP07007.1 - 2.6e-08 33.6 0.0 6.9e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat GDP_Man_Dehyd PF16363.5 KFP07007.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase MT-A70 PF05063.14 KFP07008.1 - 2.9e-63 212.9 0.0 3.9e-63 212.4 0.0 1.2 1 0 0 1 1 1 1 MT-A70 SRCR PF00530.18 KFP07009.1 - 4.7e-118 386.4 30.6 6e-33 113.3 4.3 4.1 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFP07009.1 - 4.6e-23 81.6 17.6 2e-06 28.3 1.5 4.6 4 1 0 4 4 4 4 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFP07009.1 - 4.9e-10 39.9 0.4 0.47 11.0 0.1 4.6 4 0 0 4 4 4 4 Hepsin, SRCR domain HMG_CoA_synt_N PF01154.17 KFP07009.1 - 0.1 12.4 1.7 1.7 8.4 0.0 2.7 3 0 0 3 3 3 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal HSNSD PF12062.8 KFP07010.1 - 6.6e-247 820.0 0.3 8.9e-247 819.6 0.3 1.2 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.27 KFP07010.1 - 5.7e-43 147.3 0.0 9.4e-43 146.6 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP07010.1 - 7.6e-09 36.3 0.2 0.00034 21.1 0.0 2.5 1 1 1 2 2 2 2 Sulfotransferase family RVT_1 PF00078.27 KFP07011.1 - 0.092 12.2 0.0 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFP07012.1 - 0.0028 17.2 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HSNSD PF12062.8 KFP07014.1 - 1.1e-243 809.4 0.0 1.5e-243 809.0 0.0 1.2 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.27 KFP07014.1 - 1.2e-41 143.0 0.0 2e-41 142.3 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP07014.1 - 1.6e-09 38.5 0.2 2.1e-05 25.0 0.0 2.4 1 1 1 2 2 2 2 Sulfotransferase family UDPGT PF00201.18 KFP07015.1 - 2.8e-121 405.8 0.0 3.4e-121 405.5 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KFP07015.1 - 1.4e-06 28.4 0.0 2.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Imm39 PF15568.6 KFP07015.1 - 0.0033 17.5 0.1 0.0063 16.6 0.1 1.4 1 0 0 1 1 1 1 Immunity protein 39 Glyco_trans_1_4 PF13692.6 KFP07015.1 - 0.15 12.5 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 RVT_1 PF00078.27 KFP07016.1 - 0.055 13.0 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFP07017.1 - 0.072 12.6 0.0 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Sulfatase PF00884.23 KFP07018.1 - 3.2e-45 154.9 0.1 4.7e-45 154.3 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KFP07018.1 - 3.3e-05 24.6 0.0 8.1e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Sortilin-Vps10 PF15902.5 KFP07019.1 - 4.1e-93 312.6 0.3 6.9e-93 311.9 0.3 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KFP07019.1 - 4.1e-36 124.9 5.8 6.2e-36 124.3 5.8 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal PKD PF00801.20 KFP07019.1 - 4.5e-08 32.8 0.0 7e-07 29.0 0.0 2.6 2 0 0 2 2 2 1 PKD domain BNR PF02012.20 KFP07019.1 - 0.0003 20.3 10.3 2.4 8.5 0.3 5.2 5 0 0 5 5 5 3 BNR/Asp-box repeat PH PF00169.29 KFP07020.1 - 2.3e-26 92.3 1.3 1.2e-12 48.2 0.7 2.7 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 KFP07020.1 - 7.7e-05 23.0 0.9 1.7 9.0 0.4 4.1 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 KFP07020.1 - 9.4e-05 22.8 6.1 0.026 14.9 0.0 4.2 4 1 0 4 4 4 2 Pleckstrin homology domain Sharpin_PH PF16764.5 KFP07020.1 - 0.0034 17.1 0.1 0.014 15.1 0.0 2.1 3 0 0 3 3 3 1 Sharpin PH domain ERM PF00769.19 KFP07020.1 - 0.0063 16.4 9.1 0.0063 16.4 9.1 2.0 3 0 0 3 3 3 1 Ezrin/radixin/moesin family Nup188_C PF18378.1 KFP07020.1 - 0.057 12.2 1.1 0.092 11.6 1.1 1.3 1 0 0 1 1 1 0 Nuclear pore protein NUP188 C-terminal domain Spc7 PF08317.11 KFP07020.1 - 0.13 11.1 15.5 0.27 10.1 15.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Ntox15 PF15604.6 KFP07020.1 - 0.75 9.9 6.6 2.3 8.3 6.6 1.9 1 0 0 1 1 1 0 Novel toxin 15 Prefoldin_2 PF01920.20 KFP07020.1 - 1.2 9.1 18.4 0.51 10.3 4.7 3.1 3 0 0 3 3 3 0 Prefoldin subunit AbLIM_anchor PF16182.5 KFP07021.1 - 6.2e-119 398.2 28.9 1.1e-76 259.2 21.6 2.2 1 1 1 2 2 2 2 Putative adherens-junction anchoring region of AbLIM LIM PF00412.22 KFP07021.1 - 7.7e-41 138.1 42.5 8.6e-14 51.5 2.8 4.3 4 0 0 4 4 4 4 LIM domain VHP PF02209.19 KFP07021.1 - 6e-16 58.2 2.5 1.2e-15 57.3 2.5 1.5 1 0 0 1 1 1 1 Villin headpiece domain TPR_12 PF13424.6 KFP07022.1 - 8.4e-19 67.6 37.4 2.9e-05 24.3 3.5 7.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 KFP07022.1 - 1.4e-05 24.7 39.1 0.031 14.1 0.2 11.0 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFP07022.1 - 3.1e-05 23.7 43.1 0.32 11.2 0.4 11.1 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFP07022.1 - 7.6e-05 22.6 54.0 0.018 15.2 0.4 12.3 13 2 2 15 15 15 4 Tetratricopeptide repeat TPR_10 PF13374.6 KFP07022.1 - 9.3e-05 22.2 22.9 0.044 13.7 0.7 8.8 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFP07022.1 - 0.00027 20.7 20.9 0.039 14.0 0.2 8.0 9 0 0 9 9 9 2 Tetratricopeptide repeat SH3_1 PF00018.28 KFP07022.1 - 0.0017 17.9 0.1 0.017 14.7 0.0 2.4 2 0 0 2 2 2 1 SH3 domain TPR_19 PF14559.6 KFP07022.1 - 0.018 15.6 13.2 0.027 15.0 0.3 5.7 5 1 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFP07022.1 - 0.029 15.0 19.1 0.08 13.6 0.3 7.4 9 1 0 9 9 9 0 Tetratricopeptide repeat Csd3_N PF18059.1 KFP07022.1 - 0.11 13.1 0.0 0.4 11.2 0.0 2.0 1 0 0 1 1 1 0 Csd3 N-terminal Trypsin_2 PF13365.6 KFP07023.1 - 2.2e-29 103.3 0.1 3e-29 102.9 0.1 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KFP07023.1 - 6.2e-15 55.6 0.0 8.5e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 KFP07023.1 - 2e-05 23.5 1.5 0.027 13.1 0.2 2.1 2 0 0 2 2 2 2 Peptidase S46 Peptidase_S32 PF05579.13 KFP07023.1 - 0.00066 19.0 0.1 0.3 10.2 0.0 2.1 2 0 0 2 2 2 2 Equine arteritis virus serine endopeptidase S32 DUF31 PF01732.16 KFP07023.1 - 0.013 15.0 0.2 3.6 7.0 0.0 2.1 2 0 0 2 2 2 0 Putative peptidase (DUF31) AdoMet_MTase PF07757.13 KFP07024.1 - 2.9e-41 140.3 0.1 5.5e-41 139.4 0.1 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MetW PF07021.12 KFP07024.1 - 0.017 14.8 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.6 KFP07024.1 - 0.026 14.3 0.0 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 KFP07024.1 - 0.041 13.9 0.0 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 KFP07024.1 - 0.17 11.5 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain 7tm_1 PF00001.21 KFP07025.1 - 2e-35 122.4 19.2 2.5e-35 122.1 19.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 KFP07025.1 - 0.5 10.1 14.2 0.73 9.6 13.1 1.8 1 1 1 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 Peptidase_M14 PF00246.24 KFP07026.1 - 7.9e-75 252.3 0.0 1e-74 251.9 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Fz PF01392.22 KFP07026.1 - 2e-20 73.4 2.7 4.5e-20 72.3 2.7 1.6 1 0 0 1 1 1 1 Fz domain CarboxypepD_reg PF13620.6 KFP07026.1 - 1.2e-15 57.5 0.0 2.5e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KFP07026.1 - 3.7e-07 30.1 0.0 6.2e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 CarboxypepD_reg-like domain AstE_AspA PF04952.14 KFP07026.1 - 0.0099 15.0 0.0 1.3 8.1 0.0 2.6 2 1 0 2 2 2 2 Succinylglutamate desuccinylase / Aspartoacylase family Glypican PF01153.19 KFP07026.1 - 0.016 14.1 1.1 0.024 13.5 1.1 1.1 1 0 0 1 1 1 0 Glypican RVT_1 PF00078.27 KFP07027.1 - 2.1e-14 53.6 0.0 3.7e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 KFP07027.1 - 6.7e-14 51.5 0.3 1e-13 50.9 0.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase thumb domain AHD PF17793.1 KFP07027.1 - 0.17 11.7 1.2 22 4.9 0.0 3.3 3 1 1 4 4 4 0 ANC1 homology domain (AHD) Homeodomain PF00046.29 KFP07028.1 - 1.2e-19 69.9 1.3 1.7e-19 69.4 1.3 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP07028.1 - 0.013 15.4 0.1 0.026 14.4 0.1 1.5 1 0 0 1 1 1 0 Homeobox KN domain 7tm_1 PF00001.21 KFP07029.1 - 1.7e-75 253.7 4.4 2.3e-75 253.4 4.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP07029.1 - 4.6e-09 36.0 17.7 4.1e-06 26.4 7.5 2.3 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP07029.1 - 5.7e-07 29.4 7.2 5.7e-07 29.4 7.2 2.6 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP07029.1 - 6e-07 29.5 10.1 1.7e-06 28.0 2.1 2.4 3 0 0 3 3 3 2 Olfactory receptor 7TM_GPCR_Srv PF10323.9 KFP07029.1 - 1e-06 28.3 12.8 0.00033 20.1 2.7 2.3 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv FA_desaturase PF00487.24 KFP07029.1 - 0.0089 15.9 1.6 0.035 13.9 0.0 2.4 2 0 0 2 2 2 1 Fatty acid desaturase Alpha-2-MRAP_C PF06401.11 KFP07030.1 - 9.6e-73 244.6 30.1 9.6e-73 244.6 30.1 1.6 2 0 0 2 2 2 1 Alpha-2-macroglobulin RAP, C-terminal domain Alpha-2-MRAP_N PF06400.11 KFP07030.1 - 3.4e-26 91.5 29.4 6.9e-23 80.9 3.9 3.5 2 1 1 3 3 3 3 Alpha-2-macroglobulin RAP, N-terminal domain Med30 PF11315.8 KFP07030.1 - 0.52 10.5 13.3 0.065 13.4 6.5 2.4 1 1 1 2 2 2 0 Mediator complex subunit 30 DUF5053 PF16476.5 KFP07030.1 - 1.2 8.8 5.5 5.2 6.8 0.1 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF5053) Spectrin PF00435.21 KFP07030.1 - 8 7.0 21.4 2.5 8.6 6.1 2.9 3 1 0 3 3 3 0 Spectrin repeat IRS PF02174.17 KFP07031.1 - 9.9e-09 35.0 0.0 2.4e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 PTB domain (IRS-1 type) Trypsin PF00089.26 KFP07032.1 - 7.1e-75 251.6 0.4 1.1e-74 251.0 0.4 1.3 1 0 0 1 1 1 1 Trypsin Kringle PF00051.18 KFP07032.1 - 4.4e-25 87.8 1.3 4.4e-25 87.8 1.3 2.8 3 0 0 3 3 3 1 Kringle domain fn2 PF00040.19 KFP07032.1 - 1.6e-14 53.9 16.6 3e-14 53.0 7.3 3.1 2 0 0 2 2 2 1 Fibronectin type II domain EGF PF00008.27 KFP07032.1 - 1.8e-10 40.9 34.0 6.2e-06 26.4 11.9 4.5 4 0 0 4 4 4 2 EGF-like domain fn1 PF00039.18 KFP07032.1 - 1.2e-08 35.0 1.2 1.2e-08 35.0 1.2 3.2 3 0 0 3 3 3 1 Fibronectin type I domain DUF1986 PF09342.11 KFP07032.1 - 8.9e-06 26.1 0.0 2.2e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) EGF_2 PF07974.13 KFP07032.1 - 3e-05 24.3 35.6 0.002 18.4 12.3 4.1 3 0 0 3 3 3 2 EGF-like domain hEGF PF12661.7 KFP07032.1 - 0.0045 17.6 8.4 0.0045 17.6 8.4 4.4 3 0 0 3 3 3 1 Human growth factor-like EGF cEGF PF12662.7 KFP07032.1 - 0.64 10.0 11.4 0.1 12.5 5.1 3.1 2 0 0 2 2 2 0 Complement Clr-like EGF-like RGS12_us1 PF16613.5 KFP07033.1 - 6.9e-57 190.9 14.5 6.9e-57 190.9 14.5 3.4 4 0 0 4 4 3 1 Unstructured region of RGS12 RGS12_usC PF16612.5 KFP07033.1 - 5.4e-55 185.6 1.2 5.4e-55 185.6 1.2 3.4 4 1 0 4 4 3 1 C-terminal unstructured region of RGS12 RBD PF02196.15 KFP07033.1 - 2.2e-31 107.7 0.0 1.5e-19 69.8 0.0 2.7 2 0 0 2 2 2 2 Raf-like Ras-binding domain RGS PF00615.19 KFP07033.1 - 1.1e-27 96.7 3.1 1.9e-27 95.8 3.1 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS12_us2 PF16611.5 KFP07033.1 - 3.4e-26 91.4 5.9 3.4e-26 91.4 5.9 3.4 4 0 0 4 4 3 1 Unstructured region between RBD and GoLoco PDZ PF00595.24 KFP07033.1 - 9.4e-14 51.5 0.2 1.4e-12 47.8 0.0 3.0 3 1 1 4 4 3 1 PDZ domain GoLoco PF02188.17 KFP07033.1 - 4.4e-09 35.7 0.3 1.1e-08 34.5 0.3 1.7 1 0 0 1 1 1 1 GoLoco motif PDZ_6 PF17820.1 KFP07033.1 - 2.5e-08 33.6 0.0 6.1e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PID PF00640.23 KFP07033.1 - 0.00057 19.9 0.0 0.0017 18.4 0.0 1.7 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) TUG-UBL1 PF11470.8 KFP07033.1 - 0.00058 20.0 0.3 0.23 11.7 0.0 4.3 5 0 0 5 5 5 1 TUG ubiquitin-like domain PDZ_2 PF13180.6 KFP07033.1 - 0.00089 19.5 0.0 0.0034 17.7 0.0 2.0 1 0 0 1 1 1 1 PDZ domain PT-HINT PF07591.11 KFP07033.1 - 0.02 15.1 0.0 0.055 13.7 0.0 1.7 1 0 0 1 1 1 0 Pretoxin HINT domain Myb_DNA-bind_4 PF13837.6 KFP07034.1 - 4.2e-12 46.3 1.5 4.2e-12 46.3 1.5 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KFP07034.1 - 0.0045 17.3 0.2 0.0045 17.3 0.2 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like MCM_OB PF17207.3 KFP07034.1 - 0.87 9.4 4.5 4.6 7.1 0.1 2.5 2 1 0 2 2 2 0 MCM OB domain Myb_DNA-bind_3 PF12776.7 KFP07034.1 - 3.6 8.6 7.9 1.9 9.6 0.6 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF3652 PF12372.8 KFP07035.1 - 1.2e-21 76.3 1.8 5.6e-21 74.2 0.7 2.8 2 0 0 2 2 2 1 Huntingtin protein region HEAT PF02985.22 KFP07035.1 - 5.9e-10 38.5 5.1 0.12 12.7 0.0 8.1 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 KFP07035.1 - 9.8e-06 26.0 2.1 2 9.0 0.0 5.8 3 1 2 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.6 KFP07035.1 - 1.2e-05 25.6 0.1 3.6 8.0 0.0 5.3 3 2 2 5 5 5 2 HEAT repeats Vac14_Fab1_bd PF12755.7 KFP07035.1 - 0.003 18.1 0.4 1.8 9.2 0.0 3.9 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region Pkinase PF00069.25 KFP07036.1 - 2.3e-64 217.3 0.0 3.1e-64 216.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP07036.1 - 1.5e-34 119.5 0.0 2.1e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 KFP07036.1 - 5e-22 78.4 0.8 7.8e-22 77.8 0.1 1.7 2 0 0 2 2 2 1 Regulator of G protein signaling domain Kinase-like PF14531.6 KFP07036.1 - 3.1e-05 23.5 0.0 5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP07036.1 - 0.00029 19.7 0.0 0.0006 18.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase DUF3824 PF12868.7 KFP07036.1 - 1.8 9.2 3.4 16 6.1 0.8 2.3 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) Nop14 PF04147.12 KFP07037.1 - 1.3e-264 880.6 40.9 1.5e-264 880.4 40.9 1.0 1 0 0 1 1 1 1 Nop14-like family DUF2810 PF10928.8 KFP07037.1 - 0.028 14.4 0.6 3.9 7.5 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2810) PAP_central PF04928.17 KFP07037.1 - 2.3 7.1 5.9 3.9 6.4 4.4 2.2 2 0 0 2 2 2 0 Poly(A) polymerase central domain MFS_1 PF07690.16 KFP07038.1 - 5.9e-39 134.0 65.1 3.7e-36 124.8 37.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP07038.1 - 2.5e-12 46.4 5.9 2.5e-12 46.4 5.9 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KFP07038.1 - 1.5e-06 26.9 3.0 1.5e-06 26.9 3.0 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Abhydro_lipase PF04083.16 KFP07038.1 - 0.064 12.8 0.0 0.2 11.3 0.0 1.9 2 1 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region MFS_3 PF05977.13 KFP07038.1 - 0.1 11.0 16.5 0.28 9.5 4.4 2.3 2 1 0 2 2 2 0 Transmembrane secretion effector Deltameth_res PF16020.5 KFP07038.1 - 0.11 12.4 0.0 0.55 10.1 0.0 2.2 1 0 0 1 1 1 0 Deltamethrin resistance Aldolase_II PF00596.21 KFP07039.1 - 1.2e-44 152.4 0.1 2.3e-44 151.6 0.1 1.5 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PH PF00169.29 KFP07040.1 - 9e-20 71.2 0.5 3.1e-19 69.4 0.2 2.0 2 0 0 2 2 2 1 PH domain SH2 PF00017.24 KFP07040.1 - 1.4e-05 25.1 0.0 3.3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 SH2 domain PH_6 PF15406.6 KFP07040.1 - 0.0066 16.7 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain EABR PF12180.8 KFP07041.1 - 9.3e-16 57.1 4.5 9.3e-16 57.1 4.5 2.4 2 0 0 2 2 2 1 TSG101 and ALIX binding domain of CEP55 CC2-LZ PF16516.5 KFP07041.1 - 1.9e-08 34.6 9.5 1.9e-08 34.6 9.5 5.9 2 1 2 5 5 5 2 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator FlxA PF14282.6 KFP07041.1 - 0.0041 17.1 7.1 0.0041 17.1 7.1 6.1 1 1 3 5 5 5 1 FlxA-like protein PKcGMP_CC PF16808.5 KFP07041.1 - 0.0041 16.9 0.6 0.0041 16.9 0.6 7.3 7 2 0 8 8 8 1 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4407 PF14362.6 KFP07041.1 - 0.0063 15.9 10.6 0.0063 15.9 10.6 3.1 1 1 2 3 3 3 2 Domain of unknown function (DUF4407) PRKG1_interact PF15898.5 KFP07041.1 - 0.062 14.2 0.7 0.062 14.2 0.7 6.0 2 1 2 4 4 4 0 cGMP-dependent protein kinase interacting domain DUF1192 PF06698.11 KFP07041.1 - 0.29 11.2 0.1 0.29 11.2 0.1 5.5 5 2 2 7 7 7 0 Protein of unknown function (DUF1192) ATG16 PF08614.11 KFP07041.1 - 0.37 11.0 60.6 0.078 13.2 26.4 3.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) PhoU PF01895.19 KFP07041.1 - 6.2 7.4 13.2 0.16 12.5 3.1 3.4 3 1 0 4 4 4 0 PhoU domain FAM193_C PF15914.5 KFP07042.1 - 5.7e-31 106.1 0.9 1.4e-30 104.8 0.9 1.7 1 0 0 1 1 1 1 FAM193 family C-terminal Sec34 PF04136.15 KFP07042.1 - 0.0027 17.6 1.5 0.0027 17.6 1.5 2.9 3 1 0 3 3 3 1 Sec34-like family Desmo_N PF06771.11 KFP07042.1 - 0.056 13.8 0.9 0.43 10.9 0.4 2.4 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus zf-C3HC4_2 PF13923.6 KFP07043.1 - 3.8e-11 42.6 7.3 1.2e-10 41.0 7.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP07043.1 - 5.6e-11 42.6 6.2 1.1e-10 41.6 6.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFP07043.1 - 1.5e-10 40.9 3.9 3.7e-10 39.7 3.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFP07043.1 - 1.4e-09 37.7 5.8 2.7e-09 36.8 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP07043.1 - 4.6e-09 36.1 6.3 9e-09 35.2 6.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFP07043.1 - 6.1e-09 35.6 6.0 1.3e-08 34.5 6.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP07043.1 - 5.2e-07 29.4 11.3 6.9e-07 29.0 4.2 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KFP07043.1 - 4.3e-06 26.4 3.1 1.1e-05 25.2 3.1 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KFP07043.1 - 7.1e-05 23.0 8.0 0.00041 20.6 8.0 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KFP07043.1 - 0.00097 19.2 10.0 0.025 14.7 10.2 2.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 KFP07043.1 - 0.0021 18.1 4.5 0.0037 17.4 2.4 2.1 2 0 0 2 2 2 1 Zinc-binding RING-finger Zn_ribbon_17 PF17120.5 KFP07043.1 - 0.0062 16.1 3.8 0.012 15.2 3.8 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KFP07043.1 - 0.0079 15.9 1.9 0.023 14.5 1.9 1.9 1 1 0 1 1 1 1 RING-like zinc finger Rtf2 PF04641.12 KFP07043.1 - 0.02 14.3 7.3 0.023 14.1 5.3 2.1 1 1 1 2 2 2 0 Rtf2 RING-finger zf-P11 PF03854.14 KFP07043.1 - 0.026 14.2 2.4 0.026 14.2 2.4 2.1 2 0 0 2 2 2 0 P-11 zinc finger zinc-ribbons_6 PF07191.12 KFP07043.1 - 0.028 14.4 5.0 0.076 13.0 5.0 1.7 1 1 0 1 1 1 0 zinc-ribbons zf-RING_10 PF16685.5 KFP07043.1 - 0.034 14.3 7.8 0.083 13.0 7.8 1.7 1 1 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KFP07043.1 - 0.059 13.2 5.7 0.24 11.3 5.7 2.0 1 1 0 1 1 1 0 zf-RING of BARD1-type protein DUF1272 PF06906.11 KFP07043.1 - 0.16 12.1 5.6 0.36 11.0 5.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) IBR PF01485.21 KFP07043.1 - 0.23 11.7 6.5 1.2 9.5 6.2 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-ANAPC11 PF12861.7 KFP07043.1 - 0.24 11.4 3.6 0.5 10.5 3.6 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.7 KFP07043.1 - 0.33 11.0 6.6 0.18 11.9 2.5 2.1 1 1 0 1 1 1 0 Double zinc ribbon FYVE PF01363.21 KFP07043.1 - 1.2 9.4 9.5 8.1 6.7 8.0 2.5 1 1 1 2 2 2 0 FYVE zinc finger zf-Nse PF11789.8 KFP07043.1 - 1.2 9.0 7.5 2.5 8.0 6.1 2.3 2 1 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit BUD22 PF09073.10 KFP07043.1 - 1.2 8.4 5.4 1.4 8.1 5.4 1.1 1 0 0 1 1 1 0 BUD22 Zn-ribbon_8 PF09723.10 KFP07043.1 - 1.4 9.1 6.9 3.7 7.7 2.6 2.6 2 0 0 2 2 2 0 Zinc ribbon domain FANCL_C PF11793.8 KFP07043.1 - 1.5 9.1 7.9 6.6 7.0 5.6 2.7 2 1 0 2 2 1 0 FANCL C-terminal domain Prim_Zn_Ribbon PF08273.12 KFP07043.1 - 2.3 8.6 5.2 0.86 9.9 1.2 2.2 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase FYVE PF01363.21 KFP07045.1 - 3.7e-19 68.6 11.9 3.7e-19 68.6 11.9 2.9 3 0 0 3 3 3 1 FYVE zinc finger DUF4668 PF15701.5 KFP07045.1 - 3.2 7.6 4.7 7.6 6.3 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) HAUS-augmin3 PF14932.6 KFP07046.1 - 9.1e-73 245.0 23.4 9.1e-73 245.0 23.4 3.3 2 1 0 3 3 3 1 HAUS augmin-like complex subunit 3 Baculo_PEP_C PF04513.12 KFP07046.1 - 0.028 14.5 18.1 0.049 13.7 2.5 3.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1192 PF06698.11 KFP07046.1 - 0.17 11.9 8.7 0.56 10.3 0.9 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DNA_pol_A PF00476.20 KFP07047.1 - 1.9e-125 418.8 1.9 3e-125 418.2 1.9 1.3 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_P_Exo PF18049.1 KFP07047.1 - 1.2e-86 289.5 3.9 2.8e-86 288.3 3.9 1.6 1 0 0 1 1 1 1 DNA polymerase nu pseudo-exo DUF4795 PF16043.5 KFP07047.1 - 0.29 10.7 7.0 1.9 8.0 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Mod_r PF07200.13 KFP07047.1 - 3.2 7.9 8.3 2.4 8.2 0.1 3.8 3 1 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Acetyltransf_1 PF00583.25 KFP07048.1 - 2.2e-14 53.7 0.1 2.8e-14 53.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFP07048.1 - 3.8e-13 49.7 0.0 5.2e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFP07048.1 - 5e-12 45.9 0.1 6.7e-12 45.5 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFP07048.1 - 2.7e-06 27.4 0.0 8.9e-06 25.8 0.0 1.8 1 1 1 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 KFP07048.1 - 9.3e-05 23.1 0.1 0.00012 22.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KFP07048.1 - 0.00033 20.2 0.1 0.002 17.6 0.1 1.9 1 1 0 1 1 1 1 Putative acetyl-transferase FR47 PF08445.10 KFP07048.1 - 0.0025 17.7 1.0 0.0047 16.9 0.1 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.6 KFP07048.1 - 0.0032 17.2 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFP07048.1 - 0.012 15.7 0.2 0.053 13.6 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFP07048.1 - 0.016 15.4 0.0 0.021 15.0 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KFP07048.1 - 0.065 12.8 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Neuropep_like PF15161.6 KFP07049.1 - 6.4e-29 99.4 0.2 7.9e-29 99.1 0.2 1.1 1 0 0 1 1 1 1 Neuropeptide-like Neuropep_like PF15161.6 KFP07050.1 - 1e-41 140.4 1.0 1.7e-41 139.7 1.0 1.3 1 0 0 1 1 1 1 Neuropeptide-like PWWP PF00855.17 KFP07051.1 - 6.6e-42 141.9 11.0 9.9e-22 77.2 1.7 3.8 3 0 0 3 3 3 2 PWWP domain SET PF00856.28 KFP07051.1 - 7e-22 78.6 0.3 7e-22 78.6 0.3 4.6 3 2 0 4 4 4 1 SET domain C5HCH PF17982.1 KFP07051.1 - 2.2e-19 69.3 13.5 2.2e-19 69.3 13.5 4.5 4 0 0 4 4 4 1 NSD Cys-His rich domain AWS PF17907.1 KFP07051.1 - 5.2e-17 61.6 8.4 5.2e-17 61.6 8.4 3.5 3 0 0 3 3 3 1 AWS domain PHD PF00628.29 KFP07051.1 - 5.4e-14 51.8 65.2 1.7e-06 27.8 2.9 6.5 4 2 2 6 6 6 3 PHD-finger HMG_box PF00505.19 KFP07051.1 - 6.5e-12 45.7 0.1 2.6e-11 43.8 0.1 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box zf-HC5HC2H PF13771.6 KFP07051.1 - 1.7e-06 28.2 63.0 0.0058 16.8 0.2 7.5 4 2 2 6 6 6 4 PHD-like zinc-binding domain HMG_box_2 PF09011.10 KFP07051.1 - 8.4e-05 23.1 0.2 0.0004 20.9 0.2 2.2 1 0 0 1 1 1 1 HMG-box domain zf-HC5HC2H_2 PF13832.6 KFP07051.1 - 0.0044 17.2 1.7 0.0044 17.2 1.7 6.5 3 2 3 6 6 6 3 PHD-zinc-finger like domain LETM1 PF07766.13 KFP07052.1 - 6.9e-110 366.6 8.0 6.9e-110 366.6 8.0 3.7 2 1 2 4 4 4 1 LETM1-like protein EF-hand_6 PF13405.6 KFP07052.1 - 0.0034 17.2 0.2 0.95 9.6 0.1 3.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 KFP07052.1 - 0.0081 15.6 0.2 0.22 11.1 0.1 3.0 2 0 0 2 2 2 1 EF hand SAP PF02037.27 KFP07052.1 - 0.015 15.0 0.2 0.015 15.0 0.2 3.3 3 0 0 3 3 3 0 SAP domain EF-hand_8 PF13833.6 KFP07052.1 - 0.036 13.9 0.3 0.81 9.6 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain pair MinC_N PF05209.13 KFP07052.1 - 0.057 13.4 0.6 0.77 9.7 0.0 3.0 3 0 0 3 3 3 0 Septum formation inhibitor MinC, N-terminal domain EF-hand_7 PF13499.6 KFP07052.1 - 0.18 12.3 0.1 0.18 12.3 0.1 3.7 4 1 0 4 4 4 0 EF-hand domain pair Acetyltransf_11 PF13720.6 KFP07052.1 - 0.94 10.0 4.2 0.66 10.5 0.2 2.9 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 TolA_bind_tri PF16331.5 KFP07052.1 - 4.5 7.4 11.1 0.83 9.8 3.2 3.3 2 1 1 3 3 3 0 TolA binding protein trimerisation Pkinase_Tyr PF07714.17 KFP07053.1 - 6.7e-105 350.0 0.0 1e-104 349.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP07053.1 - 1e-44 152.9 0.0 1.4e-44 152.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.16 KFP07053.1 - 8.6e-37 125.1 0.0 5.4e-14 52.0 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP07053.1 - 7.3e-36 122.6 0.2 1.7e-12 47.7 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFP07053.1 - 8.4e-27 93.3 0.1 5.6e-10 39.4 0.0 3.7 3 1 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFP07053.1 - 2.7e-24 85.1 0.2 6.6e-08 32.6 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFP07053.1 - 1.2e-14 54.4 8.1 2.7e-05 24.3 0.1 5.5 4 3 0 5 5 5 3 Immunoglobulin V-set domain FGFR3_TM PF18123.1 KFP07053.1 - 5.6e-13 48.2 4.9 9.3e-13 47.5 4.9 1.4 1 0 0 1 1 1 1 Fibroblast growth factor receptor 3 transmembrane domain Ig_5 PF16681.5 KFP07053.1 - 1.3e-08 35.1 0.0 0.62 10.5 0.0 4.1 3 1 0 3 3 3 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFP07053.1 - 3.5e-08 33.6 0.0 0.00062 20.0 0.0 3.9 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFP07053.1 - 4.3e-06 26.2 0.0 0.69 9.5 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 KFP07053.1 - 0.0006 19.8 0.2 0.051 13.6 0.0 3.1 3 1 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFP07053.1 - 0.0064 16.5 0.0 19 5.4 0.0 3.5 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain V-set_CD47 PF08204.11 KFP07053.1 - 0.034 14.1 1.0 0.98 9.4 0.0 3.1 3 1 0 3 3 3 0 CD47 immunoglobulin-like domain Kinase-like PF14531.6 KFP07053.1 - 0.083 12.2 0.0 0.2 10.9 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 KFP07053.1 - 0.16 10.7 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase TACC_C PF05010.14 KFP07054.1 - 3.1e-89 298.1 39.4 6.1e-89 297.1 39.4 1.5 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal BPTA PF17044.5 KFP07054.1 - 0.0066 16.3 1.6 0.012 15.5 1.6 1.4 1 0 0 1 1 1 1 Borrelial persistence in ticks protein A PPP5 PF08321.12 KFP07054.1 - 0.035 14.4 4.1 0.096 13.0 4.1 1.8 1 0 0 1 1 1 0 PPP5 TPR repeat region MAD PF05557.13 KFP07054.1 - 0.41 9.0 37.7 0.025 13.0 21.5 2.2 1 1 1 2 2 2 0 Mitotic checkpoint protein HTH_37 PF13744.6 KFP07054.1 - 0.52 10.3 4.0 1.3 9.0 0.5 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain ZapD PF07072.11 KFP07054.1 - 3.8 7.2 16.9 0.016 15.0 2.1 3.1 2 1 1 3 3 3 0 Cell division protein DUF3584 PF12128.8 KFP07054.1 - 8.1 3.8 33.5 0.084 10.4 23.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) DUF2508 PF10704.9 KFP07054.1 - 8.2 6.7 17.1 1.9 8.7 2.8 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2508) DUF948 PF06103.11 KFP07054.1 - 8.8 6.7 6.1 8.7 6.7 0.4 3.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Tmpp129 PF10272.9 KFP07055.1 - 1.9e-140 468.2 1.5 2.1e-140 468.1 1.5 1.0 1 0 0 1 1 1 1 Putative transmembrane protein precursor C1_4 PF07975.12 KFP07055.1 - 0.022 15.0 2.0 0.022 15.0 2.0 2.6 1 1 1 2 2 2 0 TFIIH C1-like domain DUF3577 PF12101.8 KFP07055.1 - 0.087 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3577) SNAD4 PF18750.1 KFP07055.1 - 0.33 11.1 8.8 0.4 10.8 0.2 2.4 1 1 1 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 IBR PF01485.21 KFP07055.1 - 2.9 8.2 18.5 2.5 8.4 0.5 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain SLBP_RNA_bind PF15247.6 KFP07056.1 - 8.5e-30 102.7 4.0 2.1e-29 101.4 4.0 1.7 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain FAM53 PF15242.6 KFP07057.1 - 1.5e-118 396.1 19.8 2.1e-118 395.6 19.8 1.2 1 0 0 1 1 1 1 Family of FAM53 Phospholip_A2_3 PF09056.11 KFP07058.1 - 0.045 14.4 1.7 0.15 12.7 1.1 1.9 2 0 0 2 2 2 0 Prokaryotic phospholipase A2 DUF4060 PF13269.6 KFP07058.1 - 0.049 13.7 0.2 0.089 12.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4060) Fib_alpha PF08702.10 KFP07058.1 - 0.61 10.3 6.4 0.62 10.2 1.5 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1366 PF07104.11 KFP07058.1 - 1.4 8.6 6.1 0.54 10.0 3.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) EspB PF05802.11 KFP07058.1 - 1.4 8.9 6.9 1.2 9.1 4.5 2.1 2 1 0 2 2 2 0 Enterobacterial EspB protein Eapp_C PF10238.9 KFP07058.1 - 1.4 9.0 5.3 2.7 8.0 5.3 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein DLP_helical PF18709.1 KFP07058.1 - 3.3 6.8 11.7 1.2 8.3 5.6 2.2 1 1 0 2 2 2 0 Dynamin-like helical domain AAA_11 PF13086.6 KFP07058.1 - 9.5 5.9 8.9 16 5.1 8.9 1.4 1 1 0 1 1 1 0 AAA domain CLTH PF10607.9 KFP07059.1 - 6.6e-29 100.7 0.4 1.2e-28 99.9 0.4 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Mic1 PF07035.12 KFP07059.1 - 0.001 18.8 1.8 0.0018 18.0 0.1 2.1 3 0 0 3 3 3 1 Colon cancer-associated protein Mic1-like zf-RING_UBOX PF13445.6 KFP07059.1 - 0.0047 16.9 0.4 0.36 10.9 0.0 2.8 2 0 0 2 2 2 1 RING-type zinc-finger TFIID_NTD2 PF04494.15 KFP07059.1 - 0.067 13.4 0.2 0.17 12.2 0.1 1.7 2 0 0 2 2 2 0 WD40 associated region in TFIID subunit, NTD2 domain LisH PF08513.11 KFP07059.1 - 0.24 11.4 0.7 0.38 10.8 0.0 1.8 2 0 0 2 2 2 0 LisH 2-Hacid_dh_C PF02826.19 KFP07060.1 - 2.5e-57 193.1 0.0 3.6e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFP07060.1 - 5.6e-29 100.5 0.0 6.9e-29 100.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFP07060.1 - 1.5e-05 25.3 0.0 3.2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 KFP07060.1 - 0.038 14.5 0.1 0.14 12.7 0.0 2.0 2 0 0 2 2 2 0 XdhC Rossmann domain Cellsynth_D PF03500.13 KFP07060.1 - 0.06 13.2 0.0 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 Cellulose synthase subunit D Spond_N PF06468.13 KFP07062.1 - 1.4e-77 260.2 0.5 1.9e-77 259.7 0.5 1.2 1 0 0 1 1 1 1 Spondin_N TSP_1 PF00090.19 KFP07062.1 - 0.015 15.5 2.9 0.028 14.6 2.9 1.5 1 0 0 1 1 1 0 Thrombospondin type 1 domain EMP24_GP25L PF01105.24 KFP07063.1 - 1.9e-43 148.6 0.6 2.1e-43 148.4 0.6 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4665 PF15679.5 KFP07063.1 - 0.0053 17.4 1.5 0.0083 16.7 1.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4665) FapA PF03961.13 KFP07063.1 - 0.024 13.3 0.5 0.03 12.9 0.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-RING_5 PF14634.6 KFP07064.1 - 1.9e-09 37.3 12.6 1.9e-09 37.3 12.6 1.8 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP07064.1 - 0.0017 18.2 14.7 0.011 15.6 14.6 2.2 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFP07064.1 - 0.016 15.1 10.4 0.016 15.1 10.4 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Flp_N PF03930.14 KFP07064.1 - 0.029 14.3 0.8 0.046 13.7 0.8 1.3 1 0 0 1 1 1 0 Recombinase Flp protein N-terminus zf-RING_2 PF13639.6 KFP07064.1 - 0.057 13.8 12.4 0.17 12.3 12.4 1.9 1 1 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 KFP07064.1 - 0.11 12.5 12.5 0.46 10.5 12.2 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFP07064.1 - 1.1 9.2 14.4 14 5.6 13.7 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KFP07064.1 - 1.4 8.3 9.9 2.4 7.5 9.8 1.4 1 1 0 1 1 1 0 Rtf2 RING-finger I-set PF07679.16 KFP07065.1 - 2.1e-47 159.1 0.0 1.2e-17 63.7 0.0 3.4 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP07065.1 - 1e-41 141.4 0.1 5.4e-15 55.8 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFP07065.1 - 3.6e-30 104.0 0.3 2.7e-11 43.5 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFP07065.1 - 3.8e-27 94.4 0.1 1.8e-11 44.2 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFP07065.1 - 8.9e-20 70.9 1.0 0.00016 21.8 0.1 5.2 3 2 0 4 4 4 3 Immunoglobulin V-set domain Ig_6 PF18452.1 KFP07065.1 - 1.5e-10 40.4 0.1 0.042 13.4 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_4 PF16680.5 KFP07065.1 - 1.8e-08 34.5 0.3 0.0029 17.8 0.1 3.7 4 0 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFP07065.1 - 4.5e-07 30.2 0.0 0.035 14.5 0.0 3.5 4 0 0 4 4 4 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KFP07065.1 - 1.1e-05 25.4 0.2 0.0017 18.4 0.0 3.0 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFP07065.1 - 5.1e-05 23.3 0.1 1.6 8.9 0.0 3.3 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 KFP07065.1 - 7e-05 23.0 0.0 1.1 9.4 0.0 3.2 3 0 0 3 3 3 2 Natural killer cell receptor 2B4 G6B PF15096.6 KFP07065.1 - 0.025 14.4 0.0 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 G6B family zf-RRN7 PF11781.8 KFP07065.1 - 0.029 14.0 0.2 8.4 6.2 0.0 3.5 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 V-set_CD47 PF08204.11 KFP07065.1 - 0.15 12.0 0.2 2 8.4 0.0 2.3 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain HLH PF00010.26 KFP07066.1 - 6.8e-06 25.9 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Glyco_transf_29 PF00777.18 KFP07067.1 - 2e-76 257.0 0.0 2.5e-76 256.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) PPR_2 PF13041.6 KFP07068.1 - 7e-23 80.6 7.3 3.4e-07 30.4 0.1 7.6 7 1 1 8 8 8 3 PPR repeat family PPR_3 PF13812.6 KFP07068.1 - 8.5e-14 51.4 0.9 3.6e-06 27.0 0.0 4.1 5 1 0 5 5 5 2 Pentatricopeptide repeat domain PPR_long PF17177.4 KFP07068.1 - 3e-07 30.0 0.0 0.04 13.3 0.0 3.3 1 1 2 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KFP07068.1 - 5.1e-07 29.3 0.4 3.8 7.3 0.2 6.6 6 2 1 7 7 7 3 PPR repeat PPR PF01535.20 KFP07068.1 - 4.8e-06 26.4 15.7 0.19 12.1 0.1 8.6 11 0 0 11 11 11 2 PPR repeat ECSIT PF06239.11 KFP07068.1 - 0.0046 16.1 0.4 0.89 8.6 0.2 2.6 2 0 0 2 2 2 2 Evolutionarily conserved signalling intermediate in Toll pathway Mitofilin PF09731.9 KFP07069.1 - 4.4e-210 699.7 40.6 5.1e-210 699.5 40.6 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Carm_PH PF17888.1 KFP07069.1 - 0.11 12.9 2.2 7.5 7.0 1.6 2.9 2 0 0 2 2 2 0 Carmil pleckstrin homology domain Baculo_PEP_C PF04513.12 KFP07069.1 - 0.12 12.4 14.2 0.78 9.8 0.4 4.1 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_L35p PF01632.19 KFP07070.1 - 1.2e-16 60.9 5.4 1.7e-16 60.5 5.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L35 IL33 PF15095.6 KFP07070.1 - 0.029 13.8 1.1 0.033 13.6 1.1 1.1 1 0 0 1 1 1 0 Interleukin 33 TB2_DP1_HVA22 PF03134.19 KFP07071.1 - 8.3e-27 92.9 10.9 1.2e-26 92.5 10.9 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2306 PF10067.9 KFP07071.1 - 0.044 14.0 0.6 0.076 13.2 0.6 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) MHCassoc_trimer PF08831.10 KFP07071.1 - 0.07 13.2 0.5 0.13 12.3 0.5 1.4 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain JmjC PF02373.22 KFP07072.1 - 2.4e-12 47.3 0.0 6.1e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase C1_2 PF03107.16 KFP07072.1 - 0.009 16.3 4.3 0.009 16.3 4.3 2.0 2 0 0 2 2 2 1 C1 domain DUF2610 PF11020.8 KFP07072.1 - 0.13 12.1 0.0 0.57 10.1 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2610) zf-B_box PF00643.24 KFP07072.1 - 0.8 9.9 3.8 2.9 8.1 3.8 1.9 1 0 0 1 1 1 0 B-box zinc finger zf-UDP PF14569.6 KFP07072.1 - 1.3 9.2 6.4 0.15 12.2 1.1 2.2 3 0 0 3 3 3 0 Zinc-binding RING-finger Snf7 PF03357.21 KFP07073.1 - 1.3e-41 142.1 15.8 1.3e-41 142.1 15.8 1.3 2 0 0 2 2 2 1 Snf7 zf-ZPR1 PF03367.13 KFP07073.1 - 0.0093 15.8 0.9 0.0093 15.8 0.9 1.7 2 0 0 2 2 2 1 ZPR1 zinc-finger domain Cauli_AT PF03233.13 KFP07073.1 - 0.71 9.8 5.9 0.13 12.2 0.5 2.1 1 1 0 2 2 2 0 Aphid transmission protein zf-RING_2 PF13639.6 KFP07074.1 - 7.3e-10 39.0 9.8 7.3e-10 39.0 9.8 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KFP07074.1 - 1.8e-09 37.2 4.8 4.2e-09 36.0 4.8 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFP07074.1 - 6.7e-07 29.0 10.2 6.7e-07 29.0 10.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP07074.1 - 6.5e-06 25.9 8.2 1.7e-05 24.6 8.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP07074.1 - 7.5e-06 25.9 5.8 3.2e-05 23.9 5.8 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KFP07074.1 - 1.1e-05 25.6 11.2 2.6e-05 24.4 11.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFP07074.1 - 0.00011 22.0 8.0 0.00011 22.0 8.0 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFP07074.1 - 0.0034 17.2 12.5 0.0034 17.2 12.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFP07074.1 - 0.0049 16.9 8.6 0.012 15.6 8.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFP07074.1 - 0.48 10.1 13.2 1.3 8.7 13.2 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type CLTH PF10607.9 KFP07075.1 - 4.1e-32 111.1 0.0 7.8e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KFP07075.1 - 5.8e-06 26.2 0.2 1.3e-05 25.1 0.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFP07075.1 - 0.01 16.1 1.4 0.015 15.6 0.2 2.0 2 0 0 2 2 2 0 Ring finger domain Prok-RING_4 PF14447.6 KFP07075.1 - 0.025 14.4 1.5 0.67 9.9 0.1 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 SnoaL_4 PF13577.6 KFP07075.1 - 0.14 12.3 0.0 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 SnoaL-like domain zf-RING_5 PF14634.6 KFP07075.1 - 1.6 8.8 4.4 0.45 10.5 1.1 1.9 2 0 0 2 2 2 0 zinc-RING finger domain V-set PF07686.17 KFP07076.1 - 8.2e-14 51.7 0.3 1e-13 51.4 0.3 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP07076.1 - 0.0003 21.3 0.7 0.00083 19.9 0.7 1.7 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP07076.1 - 0.02 14.9 0.1 0.035 14.2 0.1 1.5 1 1 0 1 1 1 0 Immunoglobulin I-set domain zf-met PF12874.7 KFP07077.1 - 5.5e-28 96.5 18.6 8.5e-07 29.2 2.1 4.3 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP07077.1 - 9.4e-14 51.3 14.5 0.0038 17.5 0.1 4.4 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 KFP07077.1 - 5.3e-09 35.7 17.1 0.0016 18.2 1.0 4.3 4 0 0 4 4 4 3 U1 zinc finger zf-C2H2_2 PF12756.7 KFP07077.1 - 0.00043 20.6 13.7 0.37 11.2 0.0 4.1 2 2 1 4 4 4 2 C2H2 type zinc-finger (2 copies) NTPase_I-T PF01931.18 KFP07077.1 - 0.062 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF84 zf-C2H2_4 PF13894.6 KFP07077.1 - 0.076 13.9 13.3 0.95 10.5 0.0 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KFP07077.1 - 0.11 12.4 0.6 0.41 10.5 0.1 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zinc-ribbon_6 PF10005.9 KFP07077.1 - 1.5 9.6 8.4 1.2 9.9 4.3 2.3 1 1 1 2 2 2 0 zinc-ribbon domain Vps39_2 PF10367.9 KFP07077.1 - 1.6 9.2 8.1 5.9 7.4 5.5 2.7 1 1 2 3 3 3 0 Vacuolar sorting protein 39 domain 2 zf-C2H2 PF00096.26 KFP07077.1 - 3.5 8.3 13.4 4.6 7.9 0.1 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type SET PF00856.28 KFP07078.1 - 3.7e-12 47.0 0.1 8.7e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 KFP07078.1 - 1.3e-09 38.0 18.0 1.3e-09 38.0 18.0 2.9 2 1 0 2 2 2 1 MYND finger TPR_12 PF13424.6 KFP07078.1 - 0.014 15.7 0.0 0.033 14.5 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat CpXC PF14353.6 KFP07078.1 - 0.42 10.7 6.3 0.065 13.3 0.5 2.5 2 0 0 2 2 2 0 CpXC protein Lipocalin_7 PF14651.6 KFP07079.1 - 6.9e-35 119.8 4.1 7.7e-35 119.6 4.1 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family FeThRed_A PF02941.15 KFP07079.1 - 0.085 13.0 0.1 0.2 11.8 0.1 1.6 1 1 0 1 1 1 0 Ferredoxin thioredoxin reductase variable alpha chain Thr_synth_N PF14821.6 KFP07080.1 - 2.4e-24 85.4 0.0 9.7e-24 83.4 0.0 2.1 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 KFP07080.1 - 4.8e-15 55.7 0.0 2.6e-14 53.3 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4715 PF15835.5 KFP07080.1 - 0.0072 16.4 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4715) 7tm_1 PF00001.21 KFP07082.1 - 3.3e-68 229.9 27.8 3.7e-68 229.7 27.8 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP07082.1 - 8.2e-08 31.9 32.7 8.5e-07 28.6 32.7 2.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP07082.1 - 0.00062 19.6 7.6 0.00062 19.6 7.6 2.5 2 1 0 3 3 3 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP07082.1 - 0.0098 15.5 32.3 0.015 14.9 30.8 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Rib_5-P_isom_A PF06026.14 KFP07083.1 - 5.1e-58 195.5 0.0 6.7e-58 195.1 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) UPRTase PF14681.6 KFP07083.1 - 0.079 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Sugar-bind PF04198.13 KFP07083.1 - 0.084 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain Peptidase_C93 PF06035.11 KFP07083.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial transglutaminase-like cysteine proteinase BTLCP CoA_binding PF02629.19 KFP07084.1 - 2.1e-32 111.7 1.8 3e-32 111.2 0.2 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KFP07084.1 - 8.5e-23 80.9 0.0 1.4e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KFP07084.1 - 1.3e-08 34.7 0.0 2.6e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KFP07084.1 - 3.3e-05 24.4 0.0 7.9e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 CoA binding domain UQ_con PF00179.26 KFP07085.1 - 2.4e-45 153.6 0.0 2.6e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFP07085.1 - 0.075 13.3 0.0 0.075 13.3 0.0 1.2 1 0 0 1 1 1 0 RWD domain Ank_2 PF12796.7 KFP07086.1 - 2.2e-79 262.1 23.1 1e-12 48.5 0.0 12.0 3 2 8 12 12 12 12 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP07086.1 - 2.3e-67 214.9 29.8 5.3e-05 23.3 0.0 20.7 22 0 0 22 22 22 16 Ankyrin repeat Ank PF00023.30 KFP07086.1 - 3.8e-62 204.2 37.8 1.2e-08 35.0 0.0 20.1 22 1 0 22 22 22 10 Ankyrin repeat Ank_4 PF13637.6 KFP07086.1 - 7.1e-62 205.0 23.4 2.1e-06 28.2 0.5 17.2 7 5 11 19 19 19 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP07086.1 - 3e-57 189.9 28.4 3.4e-08 33.6 0.0 15.5 12 2 3 16 16 16 10 Ankyrin repeats (many copies) FYVE PF01363.21 KFP07086.1 - 6.1e-16 58.3 10.5 1.5e-15 57.0 10.5 1.7 1 0 0 1 1 1 1 FYVE zinc finger BTB PF00651.31 KFP07086.1 - 3.9e-15 56.0 0.1 1.3e-14 54.3 0.1 2.0 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KFP07086.1 - 0.018 15.1 2.6 0.034 14.2 0.3 2.6 2 1 0 2 2 2 0 BTB And C-terminal Kelch Glyoxalase_4 PF13669.6 KFP07086.1 - 0.15 12.3 0.2 18 5.6 0.0 3.7 4 0 0 4 4 4 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FYVE_2 PF02318.16 KFP07086.1 - 1.5 9.1 12.0 0.37 11.0 7.4 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger Sec2p PF06428.11 KFP07088.1 - 0.0044 17.0 1.4 0.0047 16.9 1.4 1.1 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p RPW8 PF05659.11 KFP07088.1 - 0.055 13.1 0.1 0.059 13.1 0.1 1.1 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 E1-E2_ATPase PF00122.20 KFP07089.1 - 2e-54 183.9 0.3 2e-54 183.9 0.3 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFP07089.1 - 7.7e-45 152.8 3.9 7.7e-45 152.8 3.9 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KFP07089.1 - 5.8e-21 74.4 0.8 1.1e-20 73.6 0.8 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFP07089.1 - 1.8e-18 67.6 0.0 2.4e-17 64.0 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFP07089.1 - 7.4e-07 29.2 1.3 1.1e-06 28.5 0.3 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFP07089.1 - 0.0015 18.9 0.0 0.007 16.8 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase P2X_receptor PF00864.19 KFP07090.1 - 6e-164 545.5 0.1 7.1e-164 545.2 0.1 1.0 1 0 0 1 1 1 1 ATP P2X receptor Dickkopf_N PF04706.12 KFP07090.1 - 0.1 13.1 1.0 0.23 11.9 1.0 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region WAP PF00095.21 KFP07090.1 - 0.69 10.3 5.2 0.43 11.0 2.8 1.9 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Pkinase PF00069.25 KFP07091.1 - 7.3e-65 219.0 0.0 9.1e-64 215.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP07091.1 - 1e-32 113.5 0.0 1e-30 106.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFP07091.1 - 6.1e-08 32.3 0.0 9.3e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP07091.1 - 3.8e-05 22.7 0.0 6.3e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DER1 PF04511.15 KFP07092.1 - 6.1e-69 231.8 12.3 7e-69 231.6 12.3 1.0 1 0 0 1 1 1 1 Der1-like family Oleosin PF01277.17 KFP07092.1 - 0.026 14.3 0.0 0.026 14.3 0.0 2.2 1 1 1 2 2 2 0 Oleosin HA2 PF04408.23 KFP07093.1 - 4.1e-19 68.9 0.0 9e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFP07093.1 - 6.3e-17 61.7 0.0 1.4e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFP07093.1 - 7.6e-14 52.0 0.0 1.9e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFP07093.1 - 4.2e-05 23.4 0.1 0.0001 22.2 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFP07093.1 - 0.0077 16.5 0.0 0.032 14.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain RBM1CTR PF08081.11 KFP07093.1 - 0.061 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 RBM1CTR (NUC064) family MAM33 PF02330.16 KFP07094.1 - 2.2e-42 145.4 4.1 2.6e-42 145.2 4.1 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein PDDEXK_7 PF04411.12 KFP07094.1 - 0.065 13.2 0.1 0.15 12.0 0.1 1.6 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily RPA_interact_C PF14768.6 KFP07095.1 - 1.3e-18 67.3 4.9 1.3e-18 67.3 4.9 2.1 2 0 0 2 2 2 1 Replication protein A interacting C-terminal RPA_interact_M PF14767.6 KFP07095.1 - 5.7e-14 52.5 10.9 5.7e-14 52.5 10.9 1.7 2 0 0 2 2 2 1 Replication protein A interacting middle RPA_interact_N PF14766.6 KFP07095.1 - 2.2e-05 24.0 5.9 3.8e-05 23.2 5.9 1.4 1 0 0 1 1 1 1 Replication protein A interacting N-terminal zf-RRPl_C4 PF17026.5 KFP07095.1 - 0.065 13.3 1.4 0.2 11.7 0.7 2.1 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-RING_2 PF13639.6 KFP07095.1 - 0.42 11.0 0.1 0.42 11.0 0.1 3.2 4 1 1 5 5 5 0 Ring finger domain Zn_ribbon_SprT PF17283.2 KFP07095.1 - 1.5 8.8 6.8 0.64 10.0 2.4 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Rabaptin PF03528.15 KFP07096.1 - 5.5e-279 925.7 53.8 5.5e-279 925.7 53.8 2.6 2 1 0 2 2 2 1 Rabaptin Rab5-bind PF09311.11 KFP07096.1 - 4.7e-136 453.2 65.0 4.7e-136 453.2 65.0 4.0 2 1 1 3 3 3 1 Rabaptin-like protein Fez1 PF06818.15 KFP07096.1 - 0.0029 18.1 23.8 0.0029 18.1 23.8 5.5 2 2 2 5 5 5 2 Fez1 Laminin_II PF06009.12 KFP07096.1 - 0.0072 16.4 8.6 0.0072 16.4 8.6 7.3 3 3 5 8 8 8 2 Laminin Domain II Rep_fac_C PF08542.11 KFP07097.1 - 4.2e-27 94.4 0.0 1.1e-26 93.0 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KFP07097.1 - 1.8e-13 51.1 0.1 3e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KFP07097.1 - 3.4e-12 46.5 0.0 3.3e-10 40.0 0.1 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 KFP07097.1 - 2.9e-06 27.3 0.0 5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFP07097.1 - 5.4e-06 26.9 0.0 0.00069 20.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFP07097.1 - 5.5e-06 26.7 0.2 0.028 14.7 0.1 2.6 1 1 1 2 2 2 2 AAA domain AAA_24 PF13479.6 KFP07097.1 - 3.6e-05 23.6 0.0 7.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KFP07097.1 - 4.3e-05 23.4 0.0 8.9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 KFP07097.1 - 7.3e-05 22.7 0.0 8.9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KFP07097.1 - 0.00011 21.6 0.0 0.0018 17.7 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KFP07097.1 - 0.00077 19.8 0.5 0.0034 17.7 0.5 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFP07097.1 - 0.0012 19.4 0.0 0.0045 17.5 0.0 1.9 1 1 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 KFP07097.1 - 0.0014 18.9 0.0 0.0042 17.4 0.0 1.9 2 0 0 2 2 1 1 AAA C-terminal domain MipZ PF09140.11 KFP07097.1 - 0.0016 17.8 0.1 0.0021 17.4 0.1 1.1 1 0 0 1 1 1 1 ATPase MipZ TniB PF05621.11 KFP07097.1 - 0.002 17.5 0.1 2.2 7.6 0.0 2.4 2 0 0 2 2 2 2 Bacterial TniB protein RuvB_N PF05496.12 KFP07097.1 - 0.0034 17.1 0.0 0.0099 15.6 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KFP07097.1 - 0.004 17.2 0.0 0.011 15.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KFP07097.1 - 0.0042 16.7 0.2 0.013 15.0 0.2 1.8 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 KFP07097.1 - 0.0053 16.5 0.2 0.016 14.9 0.2 1.8 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 KFP07097.1 - 0.0068 16.2 1.1 0.42 10.4 0.0 2.7 2 1 1 3 3 3 1 DEAD/DEAH box helicase ABC_tran PF00005.27 KFP07097.1 - 0.014 15.9 0.0 0.041 14.4 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Rad17 PF03215.15 KFP07097.1 - 0.028 14.3 0.0 0.092 12.7 0.0 1.8 1 1 1 2 2 2 0 Rad17 P-loop domain ResIII PF04851.15 KFP07097.1 - 0.029 14.4 0.1 13 5.8 0.0 3.0 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 KFP07097.1 - 0.031 14.5 0.1 0.055 13.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KFP07097.1 - 0.039 13.9 0.3 0.18 11.7 0.1 2.1 2 0 0 2 2 2 0 NTPase MeaB PF03308.16 KFP07097.1 - 0.05 12.6 0.0 0.09 11.7 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2075 PF09848.9 KFP07097.1 - 0.052 12.8 0.6 1.2 8.3 0.6 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 KFP07097.1 - 0.066 12.3 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 KFP07097.1 - 0.068 13.7 0.0 0.096 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KFP07097.1 - 0.077 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 KFP07097.1 - 0.08 13.3 0.0 0.26 11.7 0.0 2.0 1 1 0 1 1 1 0 RNA helicase DUF4597 PF15366.6 KFP07097.1 - 0.085 12.6 0.7 3.1 7.6 0.1 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4597) DNA_pol3_delta PF06144.13 KFP07097.1 - 0.2 11.4 0.6 0.27 11.0 0.1 1.4 2 0 0 2 2 1 0 DNA polymerase III, delta subunit Auts2 PF15336.6 KFP07098.1 - 9.4e-106 352.8 15.3 9.4e-106 352.8 15.3 5.6 3 2 1 5 5 5 1 Autism susceptibility gene 2 protein Castor1_N PF18700.1 KFP07099.1 - 4.8e-35 119.2 2.5 2.1e-34 117.2 0.4 2.6 3 0 0 3 3 3 1 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain ACT_7 PF13840.6 KFP07099.1 - 1.4e-34 117.7 0.0 2.6e-19 68.8 0.0 2.4 2 0 0 2 2 2 2 ACT domain RCC1 PF00415.18 KFP07100.1 - 8.9e-60 199.1 15.0 4e-10 40.2 0.2 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFP07100.1 - 5.5e-30 102.5 35.2 1.6e-07 31.0 0.2 7.9 8 1 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat DUF3213 PF11491.8 KFP07100.1 - 0.21 11.8 0.0 2.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3213) SH3_1 PF00018.28 KFP07101.1 - 6.8e-30 102.4 1.0 1.5e-15 56.5 0.1 3.3 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 KFP07101.1 - 9.1e-24 83.1 0.4 1.2e-10 41.1 0.1 3.1 3 0 0 3 3 3 2 Variant SH3 domain NECFESHC PF16621.5 KFP07101.1 - 2.1e-21 75.6 13.4 2.1e-21 75.6 13.4 2.6 2 0 0 2 2 2 1 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 SH3_2 PF07653.17 KFP07101.1 - 2.6e-20 71.8 0.0 6.1e-12 45.0 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 KFP07101.1 - 3.3e-16 59.3 1.3 9.4e-16 57.8 1.3 1.7 1 0 0 1 1 1 1 PX domain p47_phox_C PF08944.11 KFP07101.1 - 7.6e-16 57.2 4.9 1.8e-15 56.0 4.9 1.7 1 0 0 1 1 1 1 NADPH oxidase subunit p47Phox, C terminal domain hSH3 PF14603.6 KFP07101.1 - 0.00022 21.6 0.0 0.086 13.3 0.0 2.5 2 0 0 2 2 2 1 Helically-extended SH3 domain SH3_3 PF08239.11 KFP07101.1 - 0.0037 17.5 1.2 0.18 12.1 0.0 2.4 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_6 PF12913.7 KFP07101.1 - 0.14 11.7 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 SH3 domain (SH3b1 type) GTF2I PF02946.14 KFP07102.1 - 3.9e-183 594.0 9.3 2.9e-30 104.2 0.0 6.2 6 0 0 6 6 6 6 GTF2I-like repeat REV1_C PF16727.5 KFP07102.1 - 0.005 17.2 3.8 32 5.0 0.0 4.4 4 0 0 4 4 4 1 DNA repair protein REV1 C-terminal domain SAVED PF18145.1 KFP07102.1 - 0.077 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 SMODS-associated and fused to various effectors sensor domain DUF1115 PF06544.12 KFP07102.1 - 0.19 11.8 7.4 0.8 9.8 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1115) Spt5_N PF11942.8 KFP07102.1 - 5.5 8.0 8.3 0.4 11.7 1.3 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal GTF2I PF02946.14 KFP07103.1 - 2.1e-157 511.5 9.7 5.4e-31 106.5 0.2 5.3 5 0 0 5 5 5 5 GTF2I-like repeat SR-25 PF10500.9 KFP07103.1 - 2.3 7.8 18.8 0.056 13.0 11.8 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Lamprin PF06403.11 KFP07104.1 - 0.84 9.6 12.7 1 9.3 3.6 1.8 1 1 0 1 1 1 0 Lamprin CAP_GLY PF01302.25 KFP07105.1 - 1.2e-48 163.0 5.2 4.5e-25 87.4 0.4 2.4 2 0 0 2 2 2 2 CAP-Gly domain Strep_SA_rep PF06696.11 KFP07105.1 - 0.22 11.6 5.1 0.95 9.5 5.1 2.2 1 0 0 1 1 1 0 Streptococcal surface antigen repeat KaiA PF07688.12 KFP07105.1 - 0.47 10.6 5.4 0.17 12.0 1.6 2.3 2 0 0 2 2 2 0 KaiA C-terminal domain Pox_A_type_inc PF04508.12 KFP07105.1 - 1.9 8.4 21.0 7.5 6.6 0.9 6.0 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat SBDS_C PF09377.10 KFP07106.1 - 6.2e-38 129.4 1.0 7.5e-38 129.1 1.0 1.1 1 0 0 1 1 1 1 SBDS protein C-terminal domain Septin PF00735.18 KFP07107.1 - 5.6e-133 442.5 0.5 6.5e-133 442.3 0.5 1.0 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 KFP07107.1 - 5.1e-08 33.0 0.2 2.4e-05 24.3 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFP07107.1 - 5.7e-08 32.8 0.0 1.1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP07107.1 - 9.3e-07 28.6 0.1 0.0047 16.5 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KFP07107.1 - 0.00032 20.1 0.1 0.00079 18.8 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Ras PF00071.22 KFP07107.1 - 0.0052 16.4 0.1 0.016 14.8 0.1 1.8 1 0 0 1 1 1 1 Ras family Dynamin_N PF00350.23 KFP07107.1 - 0.0062 16.6 2.5 0.52 10.4 0.0 2.7 2 1 1 3 3 3 1 Dynamin family Roc PF08477.13 KFP07107.1 - 0.012 15.9 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KFP07107.1 - 0.012 16.0 0.1 0.027 14.9 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KFP07107.1 - 0.017 15.7 0.0 0.029 14.9 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KFP07107.1 - 0.023 15.0 0.0 0.14 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 KFP07107.1 - 0.039 13.1 0.3 3.1 6.9 0.1 2.5 1 1 1 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.6 KFP07107.1 - 0.04 13.7 0.1 0.091 12.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Abhydrolase_6 PF12697.7 KFP07109.1 - 0.0076 16.9 0.0 0.0084 16.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2048 PF09752.9 KFP07109.1 - 0.014 14.5 0.0 0.016 14.3 0.0 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Abhydrolase_1 PF00561.20 KFP07109.1 - 0.039 13.6 0.0 0.047 13.3 0.0 1.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold Myotub-related PF06602.14 KFP07110.1 - 1e-136 455.5 0.0 1.3e-136 455.1 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 KFP07110.1 - 0.0032 17.1 0.0 0.0059 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFP07110.1 - 0.0081 16.0 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP07110.1 - 0.013 15.5 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family ZNRF_3_ecto PF18212.1 KFP07111.1 - 2.6e-49 165.5 0.0 4.1e-49 164.9 0.0 1.3 1 0 0 1 1 1 1 ZNRF-3 Ectodomain zf-RING_2 PF13639.6 KFP07111.1 - 1.7e-12 47.5 9.1 1.7e-12 47.5 9.1 2.9 3 0 0 3 3 2 1 Ring finger domain zf-RING_11 PF17123.5 KFP07111.1 - 2.1e-10 40.1 4.6 2.1e-10 40.1 4.6 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFP07111.1 - 1.7e-09 37.4 7.6 1.7e-09 37.4 7.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP07111.1 - 2.7e-07 30.3 7.7 2.7e-07 30.3 7.7 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFP07111.1 - 2.1e-06 27.9 13.9 3.3e-06 27.3 11.1 2.9 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFP07111.1 - 9.8e-06 25.5 5.1 9.8e-06 25.5 5.1 3.6 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP07111.1 - 0.00013 21.8 6.7 0.00013 21.8 6.7 2.5 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP07111.1 - 0.00018 21.3 6.2 0.0006 19.6 6.2 2.0 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF3827 PF12877.7 KFP07111.1 - 0.0065 14.9 0.2 0.01 14.3 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) zf-C3HC4_3 PF13920.6 KFP07111.1 - 0.018 14.9 4.5 0.018 14.9 4.5 2.4 3 0 0 3 3 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KFP07111.1 - 0.048 13.8 4.1 0.13 12.4 4.1 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain DUF5305 PF17231.2 KFP07111.1 - 0.094 12.1 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) RINGv PF12906.7 KFP07111.1 - 4.4 7.5 8.8 14 5.9 8.8 1.9 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 KFP07111.1 - 5.1 7.1 12.6 1.4 8.8 6.6 2.6 2 0 0 2 2 2 0 PHD-finger Spt4 PF06093.13 KFP07112.1 - 1.3e-26 92.5 0.1 1.6e-26 92.2 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Acyltransferase PF01553.21 KFP07113.1 - 1.1e-34 119.0 0.2 2.5e-34 117.8 0.0 1.6 2 0 0 2 2 2 1 Acyltransferase An_peroxidase PF03098.15 KFP07114.1 - 9.1e-179 595.4 0.0 1.2e-178 595.1 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase IL8 PF00048.20 KFP07115.1 - 2.1e-24 85.4 0.6 2.1e-24 85.4 0.6 1.7 2 0 0 2 2 2 1 Small cytokines (intecrine/chemokine), interleukin-8 like ANTH PF07651.16 KFP07116.1 - 1.6e-73 247.1 8.6 3.6e-72 242.7 0.2 2.5 2 0 0 2 2 2 2 ANTH domain I_LWEQ PF01608.17 KFP07116.1 - 1.2e-53 181.5 9.5 1.2e-53 181.5 9.5 4.1 2 1 2 4 4 4 1 I/LWEQ domain HIP1_clath_bdg PF16515.5 KFP07116.1 - 2.1e-26 92.4 15.9 2.1e-26 92.4 15.9 6.1 4 2 1 5 5 5 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Img2 PF05046.14 KFP07116.1 - 0.86 9.9 3.5 7.4 6.9 1.0 3.1 2 1 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) Pox_G5 PF04599.12 KFP07116.1 - 0.89 8.5 7.6 0.098 11.6 1.7 2.2 1 1 2 3 3 3 0 Poxvirus G5 protein ATG16 PF08614.11 KFP07116.1 - 6.4 6.9 75.6 6.9 6.8 41.2 4.1 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) POM121 PF15229.6 KFP07117.1 - 4e-102 340.8 21.0 4e-102 340.8 21.0 3.1 3 0 0 3 3 3 1 POM121 family Methyltr_RsmB-F PF01189.17 KFP07118.1 - 3.4e-34 118.3 0.0 4.9e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KFP07118.1 - 0.0014 18.8 0.0 0.002 18.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 KFP07118.1 - 0.0015 18.4 0.0 0.0057 16.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP07118.1 - 0.006 17.3 0.0 0.017 15.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFP07118.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family FKBP_C PF00254.28 KFP07119.1 - 1e-13 51.4 0.0 3.5e-13 49.7 0.0 1.9 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 KFP07119.1 - 5.5e-10 38.6 7.6 0.00083 19.3 0.1 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFP07119.1 - 1.4e-09 38.1 4.3 0.00025 21.3 0.1 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFP07119.1 - 8.7e-08 31.7 5.8 0.0012 18.6 0.3 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFP07119.1 - 8.1e-07 28.6 0.7 0.11 12.5 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP07119.1 - 0.00045 20.2 4.7 0.14 12.4 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP07119.1 - 0.00046 20.6 3.5 0.0057 17.1 1.8 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFP07119.1 - 0.0008 19.0 0.3 0.051 13.3 0.1 3.1 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.6 KFP07119.1 - 0.0029 18.2 0.5 0.082 13.6 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFP07119.1 - 0.0049 17.6 1.6 0.65 11.0 0.2 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFP07119.1 - 0.0052 16.8 2.8 0.79 9.8 0.1 2.7 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat BAR PF03114.18 KFP07119.1 - 0.0062 16.2 0.2 0.0093 15.6 0.2 1.3 1 1 0 1 1 1 1 BAR domain ANAPC3 PF12895.7 KFP07119.1 - 0.0089 16.2 6.6 0.21 11.8 1.1 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KFP07119.1 - 0.026 14.4 0.2 0.026 14.4 0.2 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Lambda_Kil PF06301.11 KFP07119.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage lambda Kil protein Frizzled PF01534.17 KFP07120.1 - 2.1e-135 450.9 20.9 2.5e-135 450.7 20.9 1.0 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 KFP07120.1 - 0.024 15.2 0.0 0.059 14.0 0.0 1.7 1 0 0 1 1 1 0 Fz domain DUF5083 PF16890.5 KFP07120.1 - 0.1 12.3 0.5 0.24 11.1 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5083) Bromodomain PF00439.25 KFP07121.1 - 7.4e-23 80.4 0.2 2.1e-22 79.0 0.2 1.8 1 0 0 1 1 1 1 Bromodomain WSD PF15613.6 KFP07121.1 - 2.3e-21 76.1 0.1 2.3e-21 76.1 0.1 4.8 5 1 0 5 5 5 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WAC_Acf1_DNA_bd PF10537.9 KFP07121.1 - 2.5e-18 66.5 0.6 2.5e-18 66.5 0.6 2.6 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal PHD PF00628.29 KFP07121.1 - 7.5e-11 41.7 2.1 2.3e-10 40.2 2.1 1.9 1 0 0 1 1 1 1 PHD-finger WHIM1 PF15612.6 KFP07121.1 - 3.4e-08 32.8 0.3 1.7e-07 30.6 0.1 2.4 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 DDT PF02791.17 KFP07121.1 - 0.00077 19.7 1.4 0.0014 18.9 0.3 2.0 2 0 0 2 2 2 1 DDT domain PHD_2 PF13831.6 KFP07121.1 - 0.041 13.4 0.4 0.1 12.1 0.4 1.8 1 0 0 1 1 1 0 PHD-finger zf-rbx1 PF12678.7 KFP07121.1 - 0.23 11.8 3.4 0.67 10.3 3.4 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KFP07121.1 - 0.25 11.7 2.8 0.63 10.4 2.8 1.7 1 0 0 1 1 1 0 Ring finger domain zf-ANAPC11 PF12861.7 KFP07121.1 - 0.29 11.2 1.4 0.72 9.9 1.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger HLH PF00010.26 KFP07122.1 - 5.5e-13 48.7 1.4 9.8e-13 47.9 0.1 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Atg14 PF10186.9 KFP07122.1 - 0.0032 16.6 2.5 0.0052 15.9 2.5 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 TolA_bind_tri PF16331.5 KFP07122.1 - 0.01 15.9 3.4 0.02 15.0 3.4 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF5082 PF16888.5 KFP07122.1 - 0.024 14.9 0.6 0.04 14.2 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Sec2p PF06428.11 KFP07122.1 - 0.044 13.8 2.4 3.6 7.6 1.9 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF384 PF04064.13 KFP07122.1 - 0.045 13.6 0.1 0.089 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF384) ZapB PF06005.12 KFP07122.1 - 0.16 12.4 5.6 0.094 13.2 3.0 1.9 2 0 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 KFP07122.1 - 0.29 10.9 3.7 0.63 9.9 3.7 1.4 1 0 0 1 1 1 0 Septum formation initiator HMMR_C PF15908.5 KFP07122.1 - 0.3 11.3 0.1 0.3 11.3 0.1 1.8 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal bZIP_1 PF00170.21 KFP07122.1 - 0.34 11.0 2.9 0.67 10.1 2.9 1.4 1 0 0 1 1 1 0 bZIP transcription factor DUF4404 PF14357.6 KFP07122.1 - 0.51 11.0 1.8 1.2 9.8 1.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) RasGAP_C PF03836.15 KFP07122.1 - 0.89 9.7 3.8 0.2 11.8 0.6 1.5 2 0 0 2 2 2 0 RasGAP C-terminus WD40 PF00400.32 KFP07123.1 - 1e-19 70.5 1.2 4e-05 24.3 0.1 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KFP07123.1 - 0.0011 18.0 0.3 0.068 12.1 0.0 2.8 2 2 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 KFP07123.1 - 0.096 12.4 0.0 0.84 9.3 0.0 2.3 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Syndecan PF01034.20 KFP07123.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain eIF2A PF08662.11 KFP07123.1 - 0.14 12.1 0.0 1.4 8.8 0.0 2.5 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A HR1 PF02185.16 KFP07123.1 - 0.24 11.6 1.4 0.39 10.8 1.4 1.3 1 0 0 1 1 1 0 Hr1 repeat AlbA_2 PF04326.14 KFP07125.1 - 8.7e-16 58.4 0.2 2.4e-12 47.2 0.0 2.5 2 0 0 2 2 2 2 Putative DNA-binding domain UvrD_C_2 PF13538.6 KFP07125.1 - 1.4e-06 28.0 0.0 3.1e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 KFP07125.1 - 1.2e-05 24.7 0.0 5.9e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KFP07125.1 - 0.00069 19.1 0.0 0.57 9.6 0.0 2.4 1 1 1 2 2 2 2 PhoH-like protein AAA_19 PF13245.6 KFP07125.1 - 0.0033 17.8 0.0 0.12 12.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KFP07125.1 - 0.0041 17.4 0.2 2.9 8.2 0.0 3.0 2 1 1 3 3 3 2 AAA domain AAA PF00004.29 KFP07125.1 - 0.0044 17.4 0.0 0.056 13.9 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 KFP07125.1 - 0.019 15.0 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 KFP07125.1 - 0.019 15.0 0.0 0.17 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Motilin_ghrelin PF04644.12 KFP07125.1 - 0.14 12.0 0.3 0.32 10.8 0.3 1.6 1 0 0 1 1 1 0 Motilin/ghrelin Syntaxin PF00804.25 KFP07126.1 - 6.6e-65 218.5 14.7 1e-64 217.9 14.7 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KFP07126.1 - 4.7e-22 77.7 4.0 1.8e-21 75.9 1.9 2.5 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 KFP07126.1 - 6.4e-12 45.7 6.6 6.4e-12 45.7 6.6 2.4 1 1 1 2 2 2 1 Syntaxin-like protein Prominin PF05478.11 KFP07126.1 - 0.0011 17.1 12.9 0.048 11.6 13.1 2.1 1 1 0 1 1 1 1 Prominin Laminin_II PF06009.12 KFP07126.1 - 0.0069 16.4 1.7 0.0069 16.4 1.7 2.4 2 1 0 2 2 2 1 Laminin Domain II GNVR PF13807.6 KFP07126.1 - 0.0077 16.1 0.1 0.043 13.7 0.0 2.1 2 0 0 2 2 2 1 G-rich domain on putative tyrosine kinase Ferritin PF00210.24 KFP07126.1 - 0.0096 15.9 0.8 0.0096 15.9 0.8 1.8 2 0 0 2 2 2 1 Ferritin-like domain DUF948 PF06103.11 KFP07126.1 - 0.015 15.6 4.4 1.2 9.4 0.3 3.8 1 1 3 4 4 3 0 Bacterial protein of unknown function (DUF948) Lzipper-MIP1 PF14389.6 KFP07126.1 - 0.028 14.7 4.4 0.033 14.5 0.2 2.6 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 WXG100 PF06013.12 KFP07126.1 - 0.037 14.2 2.1 3.5 7.9 0.2 3.6 4 0 0 4 4 4 0 Proteins of 100 residues with WXG GlutR_dimer PF00745.20 KFP07126.1 - 0.038 14.4 5.9 2.8 8.4 1.1 2.7 1 1 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain CorA PF01544.18 KFP07126.1 - 0.059 12.7 8.1 0.2 11.0 1.2 2.5 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein SIMPL PF04402.14 KFP07126.1 - 0.074 13.5 5.1 0.2 12.1 5.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF541) Syntaxin-6_N PF09177.11 KFP07126.1 - 0.11 13.0 12.3 0.054 14.1 4.2 3.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal ALIX_LYPXL_bnd PF13949.6 KFP07126.1 - 0.14 11.4 9.7 0.6 9.4 8.7 2.1 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV Sec34 PF04136.15 KFP07126.1 - 0.18 11.6 10.2 3.3 7.6 3.8 3.2 2 1 1 3 3 3 0 Sec34-like family MCPsignal PF00015.21 KFP07126.1 - 0.25 11.1 8.5 3.8 7.3 1.6 2.9 1 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2508 PF10704.9 KFP07126.1 - 0.25 11.5 3.0 1.2 9.4 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) YtxH PF12732.7 KFP07126.1 - 0.29 11.7 8.4 0.2 12.2 1.5 3.2 3 1 0 3 3 2 0 YtxH-like protein LOH1CR12 PF10158.9 KFP07126.1 - 0.41 10.7 7.6 2.7 8.0 0.8 2.6 2 1 0 2 2 2 0 Tumour suppressor protein PspA_IM30 PF04012.12 KFP07126.1 - 0.52 9.8 10.9 0.071 12.7 4.9 2.2 2 1 0 2 2 2 0 PspA/IM30 family Phage_GPO PF05929.11 KFP07126.1 - 0.63 9.6 6.9 3.4 7.2 4.7 2.7 1 1 2 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Nup54 PF13874.6 KFP07126.1 - 0.63 10.1 10.0 17 5.5 6.4 2.9 1 1 1 3 3 3 0 Nucleoporin complex subunit 54 HAUS6_N PF14661.6 KFP07126.1 - 0.81 9.2 9.7 8.4 5.9 8.0 2.4 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Lipoprotein_2 PF00921.17 KFP07126.1 - 0.81 9.2 8.1 0.059 12.9 1.6 2.2 3 0 0 3 3 3 0 Borrelia lipoprotein DUF848 PF05852.11 KFP07126.1 - 0.84 9.7 12.2 0.28 11.3 4.5 2.7 2 2 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF16 PF01519.16 KFP07126.1 - 0.85 10.1 12.7 0.36 11.4 0.7 3.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Uso1_p115_C PF04871.13 KFP07126.1 - 0.91 9.9 16.5 0.51 10.7 7.8 2.9 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Med9 PF07544.13 KFP07126.1 - 1 9.5 8.7 0.71 10.0 2.4 3.3 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF1910 PF08928.10 KFP07126.1 - 1.1 9.2 13.4 0.38 10.8 1.0 3.1 1 1 0 2 2 2 0 Domain of unknown function (DUF1910) FapA PF03961.13 KFP07126.1 - 1.1 7.8 15.4 0.079 11.5 7.2 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF745 PF05335.13 KFP07126.1 - 1.2 8.8 5.3 2.3 7.9 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) EcoEI_R_C PF08463.10 KFP07126.1 - 1.3 9.1 6.0 0.58 10.2 1.1 2.5 1 1 0 2 2 2 0 EcoEI R protein C-terminal Lge1 PF11488.8 KFP07126.1 - 1.4 9.2 9.0 0.86 9.8 0.1 3.0 3 1 0 3 3 2 0 Transcriptional regulatory protein LGE1 Herpes_UL25 PF01499.16 KFP07126.1 - 1.5 7.3 5.3 0.95 7.9 1.5 1.9 1 1 0 2 2 2 0 Herpesvirus UL25 family DUF148 PF02520.17 KFP07126.1 - 1.6 8.9 11.2 0.064 13.4 1.5 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF148 COG5 PF10392.9 KFP07126.1 - 1.7 8.8 9.1 2.6 8.2 0.7 2.7 2 1 0 2 2 2 0 Golgi transport complex subunit 5 FlaC_arch PF05377.11 KFP07126.1 - 2 8.8 15.8 4.4 7.8 2.7 4.2 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) Ead_Ea22 PF13935.6 KFP07126.1 - 2.1 9.0 9.6 0.69 10.6 2.2 2.6 2 1 0 2 2 2 0 Ead/Ea22-like protein Fez1 PF06818.15 KFP07126.1 - 3.1 8.2 17.1 3.7 7.9 0.9 2.2 2 0 0 2 2 2 0 Fez1 Fib_alpha PF08702.10 KFP07126.1 - 3.1 8.0 16.0 1.7 8.8 6.0 3.1 1 1 2 3 3 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KFP07126.1 - 3.4 7.7 13.2 4.5 7.3 3.4 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4600 PF15372.6 KFP07126.1 - 3.6 8.0 11.8 0.64 10.5 5.9 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4600) DUF4404 PF14357.6 KFP07126.1 - 3.6 8.3 8.6 1.9 9.2 2.6 3.2 1 1 3 4 4 4 0 Domain of unknown function (DUF4404) DUF883 PF05957.13 KFP07126.1 - 5.6 7.6 8.2 6.9 7.3 1.0 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) COG2 PF06148.11 KFP07126.1 - 6.3 6.9 12.8 8.5 6.5 2.8 3.5 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TMPIT PF07851.13 KFP07126.1 - 6.7 5.9 13.0 2e+02 1.0 13.1 2.3 1 1 0 1 1 1 0 TMPIT-like protein WBS_methylT PF12589.8 KFP07127.1 - 1e-19 71.1 3.7 1.5e-19 70.5 3.7 1.2 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KFP07127.1 - 5.3e-10 39.8 0.0 8.6e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP07127.1 - 2.3e-09 37.8 0.0 4.4e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP07127.1 - 0.00048 20.8 0.0 0.00091 19.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP07127.1 - 0.001 18.9 0.0 0.0019 18.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP07127.1 - 0.082 12.7 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Fibrinogen_C PF00147.18 KFP07128.1 - 2.2e-26 93.0 0.2 2.4e-26 92.9 0.2 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Ephrin_lbd PF01404.19 KFP07128.1 - 0.048 13.7 1.0 0.062 13.3 1.0 1.2 1 0 0 1 1 1 0 Ephrin receptor ligand binding domain EF-hand_1 PF00036.32 KFP07129.1 - 7.9e-17 59.5 8.8 1.1e-08 34.0 0.1 4.0 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 KFP07129.1 - 4.2e-15 55.9 1.7 1.2e-13 51.3 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP07129.1 - 9.1e-15 53.3 2.8 2.4e-08 33.3 0.0 3.7 3 1 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KFP07129.1 - 7.5e-13 48.1 8.9 8.5e-10 38.3 0.4 4.2 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP07129.1 - 2.1e-12 45.9 10.4 8.7e-06 25.0 0.1 4.2 3 1 1 4 4 4 2 EF hand EF-hand_9 PF14658.6 KFP07129.1 - 0.00097 19.4 0.0 0.0034 17.7 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 KFP07129.1 - 0.0085 16.0 0.2 0.022 14.7 0.1 1.7 1 1 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFP07129.1 - 0.014 15.7 0.3 0.051 13.9 0.0 2.0 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.10 KFP07129.1 - 0.12 12.5 0.2 0.47 10.6 0.0 2.1 2 1 0 2 2 2 0 Ca2+ insensitive EF hand Glycos_transf_2 PF00535.26 KFP07130.1 - 7.1e-29 100.8 0.0 1.2e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFP07130.1 - 2.8e-18 66.4 0.1 4.6e-18 65.7 0.1 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 KFP07130.1 - 8.4e-06 25.8 0.0 0.00066 19.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.6 KFP07130.1 - 0.0077 16.9 0.1 0.039 14.7 0.0 2.0 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Glyco_transf_7C PF02709.14 KFP07130.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase I-set PF07679.16 KFP07131.1 - 4.7e-82 270.2 1.2 2.7e-19 69.0 0.2 5.7 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP07131.1 - 5.4e-67 222.4 6.3 8e-16 58.4 0.0 5.7 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 KFP07131.1 - 2e-47 159.3 0.7 4.1e-10 39.7 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin domain Ig_2 PF13895.6 KFP07131.1 - 3.3e-47 158.7 0.5 2.1e-09 37.6 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin domain fn3 PF00041.21 KFP07131.1 - 6.3e-30 103.4 2.8 4.6e-17 62.1 1.0 2.6 2 0 0 2 2 2 2 Fibronectin type III domain V-set PF07686.17 KFP07131.1 - 1.9e-27 95.5 1.8 1.7e-05 25.0 0.0 8.3 4 3 1 5 5 5 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP07131.1 - 8.6e-14 51.4 1.6 0.0012 18.9 0.0 5.4 5 0 0 5 5 5 3 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 KFP07131.1 - 1.4e-12 47.5 0.0 0.05 13.6 0.0 5.6 5 0 0 5 5 5 3 C17orf99 Ig domain Izumo-Ig PF16706.5 KFP07131.1 - 3e-11 43.2 0.0 0.042 13.9 0.0 4.6 4 0 0 4 4 4 2 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFP07131.1 - 3.9e-10 40.0 0.3 0.065 13.7 0.0 5.2 5 1 0 5 5 5 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFP07131.1 - 1.1e-09 38.4 1.1 0.61 10.4 0.0 6.3 5 1 0 5 5 5 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFP07131.1 - 3.2e-09 36.2 0.0 1.2 8.8 0.0 5.4 5 0 0 5 5 5 2 Immunoglobulin domain Receptor_2B4 PF11465.8 KFP07131.1 - 1.2e-07 31.9 0.3 0.68 10.2 0.0 5.3 5 1 0 5 5 5 2 Natural killer cell receptor 2B4 Adeno_E3_CR1 PF02440.15 KFP07131.1 - 4.4e-06 26.4 0.1 0.39 10.5 0.0 4.0 3 0 0 3 3 3 2 Adenovirus E3 region protein CR1 Pur_ac_phosph_N PF16656.5 KFP07131.1 - 0.00031 21.2 0.3 0.0022 18.5 0.1 2.5 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Herpes_gE PF02480.16 KFP07131.1 - 0.0021 16.9 0.6 0.47 9.1 0.1 3.2 1 1 1 3 3 3 1 Alphaherpesvirus glycoprotein E Interfer-bind PF09294.10 KFP07131.1 - 0.0067 16.7 0.0 1.1 9.6 0.0 2.8 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III C2-set PF05790.15 KFP07131.1 - 0.055 13.7 0.3 9.5 6.5 0.0 4.4 5 0 0 5 5 5 0 Immunoglobulin C2-set domain Yae1_N PF09811.9 KFP07132.1 - 5.2e-16 58.1 59.3 0.0041 16.8 7.8 5.6 2 2 0 2 2 2 1 Essential protein Yae1, N terminal Hormone_recep PF00104.30 KFP07133.1 - 1.6e-39 135.6 0.1 2.4e-39 135.0 0.1 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFP07133.1 - 8.4e-31 106.2 17.1 8.4e-31 106.2 17.1 1.7 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Arrestin_C PF02752.22 KFP07134.1 - 1e-22 81.0 0.1 3.1e-21 76.2 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KFP07134.1 - 9.9e-20 71.1 0.0 2.5e-18 66.6 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 KFP07134.1 - 0.04 13.1 0.1 0.069 12.3 0.1 1.3 1 0 0 1 1 1 0 Rgp1 Vps26 PF03643.15 KFP07134.1 - 0.11 11.4 0.0 0.18 10.8 0.0 1.4 1 1 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 Sulfotransfer_2 PF03567.14 KFP07135.1 - 3.4e-33 115.6 1.2 4.4e-33 115.3 1.2 1.1 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 KFP07135.1 - 4.7e-08 32.3 0.3 6.6e-08 31.8 0.3 1.2 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase RNA_pol_Rpb1_1 PF04997.12 KFP07136.1 - 1.8e-48 165.5 0.0 2.1e-48 165.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 ANF_receptor PF01094.28 KFP07137.1 - 1.9e-36 125.9 0.0 2.1e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region TrkA_N PF02254.18 KFP07137.1 - 0.034 14.4 0.1 0.057 13.7 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain Glyco_transf_4 PF13439.6 KFP07137.1 - 0.34 10.9 2.4 0.34 10.9 0.3 2.2 2 1 0 2 2 2 0 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KFP07137.1 - 3.5 8.1 13.6 0.2 12.1 3.7 2.7 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain HNOBA PF07701.14 KFP07138.1 - 3.5e-07 29.9 0.6 3.9e-07 29.7 0.6 1.0 1 0 0 1 1 1 1 Heme NO binding associated EFP_N PF08207.12 KFP07140.1 - 0.0014 18.6 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain LRR_8 PF13855.6 KFP07141.1 - 4e-15 55.3 2.4 4e-15 55.3 2.4 2.6 2 1 0 2 2 2 1 Leucine rich repeat 7tm_2 PF00002.24 KFP07141.1 - 5.6e-13 48.7 6.8 1e-12 47.9 6.8 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 KFP07141.1 - 1.8e-08 34.8 0.2 1.8e-08 34.8 0.2 3.5 3 0 0 3 3 3 1 GPCR proteolysis site, GPS, motif LRR_4 PF12799.7 KFP07141.1 - 6.3e-08 32.8 10.3 2.8e-05 24.4 4.3 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) I-set PF07679.16 KFP07141.1 - 1.2e-07 31.7 0.0 2.6e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain HRM PF02793.22 KFP07141.1 - 5.9e-05 23.3 1.4 5.9e-05 23.3 1.4 2.4 2 0 0 2 2 2 1 Hormone receptor domain LRR_1 PF00560.33 KFP07141.1 - 0.00018 21.6 4.0 0.17 12.5 0.1 4.1 2 0 0 2 2 2 2 Leucine Rich Repeat LRR_5 PF13306.6 KFP07141.1 - 0.00053 19.9 0.9 0.0036 17.3 0.1 2.6 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) ig PF00047.25 KFP07141.1 - 0.046 13.9 0.2 0.1 12.8 0.2 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Sulfotransfer_1 PF00685.27 KFP07142.1 - 4.9e-33 114.7 0.1 6.8e-33 114.3 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP07142.1 - 7.5e-13 49.4 0.0 1.5e-08 35.3 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFP07142.1 - 0.023 14.6 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase family Cas_GSU0054 PF09609.10 KFP07142.1 - 0.14 10.9 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) DNA_pol_B_thumb PF14791.6 KFP07143.1 - 4.1e-19 68.5 0.2 9.7e-19 67.3 0.2 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 KFP07143.1 - 9.1e-18 63.8 0.1 1.7e-17 62.9 0.1 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 KFP07143.1 - 8.6e-11 42.0 0.0 3.9e-10 40.0 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_B_palm PF14792.6 KFP07143.1 - 1.5e-08 34.9 0.0 3.2e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm NTP_transf_2 PF01909.23 KFP07143.1 - 2.1e-06 27.9 0.0 6.1e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain BRCT PF00533.26 KFP07143.1 - 0.00011 22.5 0.0 0.00036 20.8 0.0 2.0 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Cdd1 PF11731.8 KFP07143.1 - 0.018 15.3 0.0 0.04 14.1 0.0 1.5 1 0 0 1 1 1 0 Pathogenicity locus HHH_5 PF14520.6 KFP07143.1 - 0.091 13.4 0.0 0.2 12.3 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain SH2 PF00017.24 KFP07144.1 - 9.8e-11 41.6 0.1 2.9e-10 40.1 0.1 1.9 2 0 0 2 2 2 1 SH2 domain zf-C2H2 PF00096.26 KFP07145.1 - 0.0016 18.8 51.2 0.22 12.0 1.5 7.9 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFP07145.1 - 0.0078 15.9 0.2 0.0078 15.9 0.2 5.3 5 0 0 5 5 5 2 C2H2-type zinc-finger domain TQ PF18202.1 KFP07145.1 - 0.12 12.9 0.3 9.6 6.8 0.1 2.6 2 0 0 2 2 2 0 T-Q ester bond containing domain zf-ZPR1 PF03367.13 KFP07145.1 - 4 7.3 11.9 0.24 11.3 2.0 3.3 2 1 1 3 3 3 0 ZPR1 zinc-finger domain zf-H2C2_2 PF13465.6 KFP07145.1 - 4.6 7.8 45.8 1.3 9.6 1.8 7.7 7 0 0 7 7 7 0 Zinc-finger double domain Cyclin_N PF00134.23 KFP07146.1 - 1.1e-19 70.4 1.4 2.6e-19 69.2 0.6 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP07146.1 - 2.9e-19 69.3 0.3 2.9e-19 69.3 0.3 3.2 3 0 0 3 3 3 2 Cyclin, C-terminal domain TFIIA PF03153.13 KFP07146.1 - 0.75 9.7 9.9 0.98 9.3 9.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3535 PF12054.8 KFP07149.1 - 9.5e-135 450.2 10.1 4.3e-131 438.2 7.6 3.7 4 0 0 4 4 4 3 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KFP07149.1 - 3.8e-51 173.9 0.0 2.6e-50 171.1 0.0 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain HEAT PF02985.22 KFP07149.1 - 1.1e-21 75.0 21.1 0.0052 16.9 0.0 13.2 12 1 0 12 12 12 6 HEAT repeat Helicase_C PF00271.31 KFP07149.1 - 2.2e-17 63.4 0.0 6.7e-17 61.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_2 PF13646.6 KFP07149.1 - 4.9e-12 46.1 3.3 0.014 15.8 0.3 6.8 5 1 2 7 7 7 4 HEAT repeats Vac14_Fab1_bd PF12755.7 KFP07149.1 - 1.9e-11 44.4 0.1 0.015 15.9 0.0 5.6 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KFP07149.1 - 2.6e-05 24.6 14.8 0.004 17.6 0.1 7.7 8 1 1 9 9 9 1 HEAT-like repeat TAF6_C PF07571.13 KFP07149.1 - 5.1e-05 23.5 0.4 2.5 8.5 0.0 6.5 5 1 2 7 7 7 1 TAF6 C-terminal HEAT repeat domain Cnd1 PF12717.7 KFP07149.1 - 0.00035 20.7 11.4 0.15 12.1 0.2 5.5 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 KFP07149.1 - 0.19 11.8 5.8 0.85 9.8 0.0 4.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat UME PF08064.13 KFP07149.1 - 0.4 10.6 4.8 44 4.1 0.0 5.1 4 1 0 4 4 4 0 UME (NUC010) domain RRM_7 PF16367.5 KFP07150.1 - 9.3e-38 128.3 0.0 6.3e-36 122.4 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif CEBP_ZZ PF16366.5 KFP07150.1 - 1.9e-20 72.8 5.8 4.9e-20 71.5 5.8 1.7 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 KFP07150.1 - 9.9e-12 44.5 0.0 1.3e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-U1 PF06220.12 KFP07150.1 - 0.037 13.8 0.6 0.086 12.6 0.6 1.6 1 0 0 1 1 1 0 U1 zinc finger SKG6 PF08693.10 KFP07150.1 - 0.33 10.4 4.4 0.67 9.4 4.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain zf-B_box PF00643.24 KFP07150.1 - 0.41 10.8 5.8 0.88 9.8 5.8 1.5 1 0 0 1 1 1 0 B-box zinc finger RINGv PF12906.7 KFP07151.1 - 1.5e-14 53.9 10.9 2.2e-14 53.3 10.9 1.3 1 0 0 1 1 1 1 RING-variant domain DUF2517 PF10725.9 KFP07151.1 - 0.0011 18.7 0.1 0.003 17.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2517) zf-RING_2 PF13639.6 KFP07151.1 - 0.0024 18.2 6.6 0.0055 17.0 6.6 1.7 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KFP07151.1 - 0.041 14.0 5.7 0.09 13.0 5.7 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KFP07151.1 - 0.44 10.4 6.0 0.95 9.3 6.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-CSL PF05207.13 KFP07151.1 - 0.5 10.1 3.2 1.1 9.0 3.2 1.5 1 1 0 1 1 1 0 CSL zinc finger PHD PF00628.29 KFP07151.1 - 1.3 9.0 8.6 2.2 8.2 8.6 1.4 1 0 0 1 1 1 0 PHD-finger Peptidase_M16_M PF16187.5 KFP07152.1 - 1.6e-99 332.7 5.8 1.6e-99 332.7 5.8 1.7 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KFP07152.1 - 3.8e-48 163.2 0.2 3.3e-46 157.0 0.1 2.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFP07152.1 - 2.8e-40 138.3 0.1 2.4e-22 79.8 0.0 3.3 4 0 0 4 4 4 2 Peptidase M16 inactive domain Tn916-Xis PF09035.10 KFP07152.1 - 0.053 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Excisionase from transposon Tn916 Kinesin PF00225.23 KFP07153.1 - 1.5e-115 385.7 0.1 1.5e-115 385.7 0.1 3.2 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bind PF13931.6 KFP07153.1 - 6.1e-47 159.4 3.7 6.1e-47 159.4 3.7 4.8 3 2 1 6 6 6 1 Kinesin-associated microtubule-binding Microtub_bd PF16796.5 KFP07153.1 - 4.4e-23 81.9 0.0 4.4e-23 81.9 0.0 3.0 3 1 1 4 4 4 1 Microtubule binding YflT PF11181.8 KFP07153.1 - 0.73 10.4 7.6 1 9.9 1.7 3.8 2 1 0 3 3 3 0 Heat induced stress protein YflT Homeodomain PF00046.29 KFP07154.1 - 0.00015 21.5 7.6 0.00034 20.4 7.6 1.6 1 0 0 1 1 1 1 Homeodomain zf-CW PF07496.15 KFP07154.1 - 0.19 11.8 1.5 0.34 11.0 1.5 1.4 1 0 0 1 1 1 0 CW-type Zinc Finger p450 PF00067.22 KFP07156.1 - 2.9e-56 191.1 0.0 4.9e-56 190.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Baculo_gp41 PF04700.12 KFP07156.1 - 0.19 11.5 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region p450 PF00067.22 KFP07157.1 - 3e-58 197.7 0.1 8.6e-52 176.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 EABR PF12180.8 KFP07158.1 - 1.3e-17 63.1 1.7 3.2e-17 61.8 1.7 1.8 1 0 0 1 1 1 1 TSG101 and ALIX binding domain of CEP55 CC2-LZ PF16516.5 KFP07158.1 - 3e-05 24.3 19.1 3e-05 24.3 19.1 4.5 3 2 2 5 5 5 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Fez1 PF06818.15 KFP07158.1 - 0.0044 17.5 19.6 0.0044 17.5 19.6 3.4 1 1 0 2 2 2 1 Fez1 GAS PF13851.6 KFP07158.1 - 0.62 9.4 70.8 0.18 11.2 12.3 4.4 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding ADIP PF11559.8 KFP07158.1 - 2.7 8.1 64.4 0.49 10.5 15.0 4.5 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Lipocalin PF00061.23 KFP07159.1 - 3.3e-24 85.7 0.0 4.8e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.12 KFP07159.1 - 6.4e-07 29.4 0.2 1.1e-06 28.7 0.2 1.4 1 1 0 1 1 1 1 Lipocalin-like domain Triabin PF03973.13 KFP07159.1 - 2.1e-05 24.4 0.9 6.2e-05 22.9 0.9 1.7 1 1 0 1 1 1 1 Triabin PDEase_I PF00233.19 KFP07160.1 - 3.4e-81 272.5 3.1 3.4e-81 272.5 3.1 2.3 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 KFP07160.1 - 3.2e-22 79.6 0.0 7e-10 39.6 0.0 2.3 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 KFP07160.1 - 2.3e-05 24.7 0.0 0.4 11.0 0.0 2.7 2 1 0 2 2 2 2 GAF domain SpoVT_C PF15714.5 KFP07160.1 - 0.0036 17.3 0.5 1.7 8.7 0.0 3.2 3 0 0 3 3 3 2 Stage V sporulation protein T C-terminal, transcription factor Fra10Ac1 PF09725.9 KFP07161.1 - 9.5e-53 177.6 5.0 2.4e-52 176.3 5.0 1.7 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 Zip PF02535.22 KFP07161.1 - 8.3 5.5 7.9 13 4.9 7.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter EPTP PF03736.17 KFP07162.1 - 1.4e-72 239.4 21.5 7.1e-13 48.3 0.1 7.2 7 0 0 7 7 7 7 EPTP domain LRR_8 PF13855.6 KFP07162.1 - 2.5e-21 75.2 10.8 2.4e-14 52.8 5.0 2.8 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KFP07162.1 - 6.2e-09 36.0 7.4 6.5e-05 23.2 2.9 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP07162.1 - 3.9e-08 33.3 0.9 3.9e-08 33.3 0.9 2.3 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP07162.1 - 0.0023 17.5 0.3 0.0089 15.5 0.3 1.7 1 1 1 2 2 2 1 Leucine-rich repeat LRRCT PF01463.24 KFP07162.1 - 0.058 14.0 0.0 0.24 12.0 0.0 2.1 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain LRR_1 PF00560.33 KFP07162.1 - 1.1 10.1 10.3 2.8 8.8 0.8 3.9 4 0 0 4 4 4 0 Leucine Rich Repeat EamA PF00892.20 KFP07163.1 - 0.00066 19.9 0.5 0.00066 19.9 0.5 1.0 1 0 0 1 1 1 1 EamA-like transporter family PI-PLC-Y PF00387.19 KFP07164.1 - 3e-34 117.8 0.0 7.3e-34 116.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain RA PF00788.23 KFP07164.1 - 1.6e-23 83.1 0.0 2.5e-18 66.5 0.1 2.4 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain C2 PF00168.30 KFP07164.1 - 2.4e-09 37.4 0.0 4.5e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain CBF PF03914.17 KFP07165.1 - 1.1e-30 106.9 0.3 5.8e-30 104.6 0.3 2.3 1 0 0 1 1 1 1 CBF/Mak21 family NOC3p PF07540.11 KFP07165.1 - 1.4e-29 102.4 1.4 1.4e-29 102.4 1.4 3.2 3 0 0 3 3 3 1 Nucleolar complex-associated protein RICTOR_N PF14664.6 KFP07165.1 - 0.25 10.3 9.6 0.93 8.4 0.7 3.2 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term DBD_HTH PF18430.1 KFP07165.1 - 0.28 11.0 4.0 0.86 9.4 1.1 2.6 2 0 0 2 2 2 0 Putative DNA-binding domain RabGAP-TBC PF00566.18 KFP07166.1 - 5.9e-50 169.9 0.0 1.1e-49 169.0 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ank_5 PF13857.6 KFP07167.1 - 1.6e-101 331.0 33.9 1.1e-13 51.1 0.2 13.9 5 5 8 13 13 13 13 Ankyrin repeats (many copies) Ank PF00023.30 KFP07167.1 - 2.1e-100 325.1 44.7 9.2e-08 32.2 0.2 18.0 18 0 0 18 18 18 15 Ankyrin repeat Ank_4 PF13637.6 KFP07167.1 - 9.7e-99 322.6 21.8 6.5e-13 48.9 0.2 13.7 6 5 7 14 14 14 14 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP07167.1 - 1.9e-97 320.0 31.0 6.9e-15 55.4 0.1 9.8 5 5 4 9 9 9 9 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP07167.1 - 1.4e-86 274.0 24.4 1.6e-06 28.0 0.1 18.0 19 0 0 19 19 19 14 Ankyrin repeat PARP PF00644.20 KFP07167.1 - 1e-25 90.5 4.1 3.1e-23 82.4 4.1 2.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SAM_2 PF07647.17 KFP07167.1 - 1.2e-13 50.9 0.1 3e-13 49.6 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFP07167.1 - 3e-11 43.6 0.1 7e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Vps39_1 PF10366.9 KFP07167.1 - 0.0028 17.9 1.1 4.3 7.7 0.0 3.4 4 0 0 4 4 4 2 Vacuolar sorting protein 39 domain 1 CBM_21 PF03370.13 KFP07168.1 - 8.5e-34 116.1 2.3 1.4e-33 115.5 2.3 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KFP07168.1 - 2.9e-17 63.0 1.6 7.8e-17 61.6 1.6 1.7 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) HECT PF00632.25 KFP07170.1 - 1.5e-84 284.1 0.3 2.2e-84 283.5 0.3 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) TipE PF16972.5 KFP07170.1 - 0.047 12.9 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE RAWUL PF16207.5 KFP07171.1 - 8.1e-13 48.9 0.4 6e-12 46.1 0.0 2.3 2 0 0 2 2 2 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 KFP07171.1 - 6.2e-10 38.7 10.8 6.2e-10 38.7 10.8 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP07171.1 - 5.5e-08 32.6 11.5 5.5e-08 32.6 11.5 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP07171.1 - 9.3e-05 22.4 11.3 9.3e-05 22.4 11.3 2.8 3 0 0 3 3 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFP07171.1 - 0.0001 22.4 10.4 0.0001 22.4 10.4 3.1 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFP07171.1 - 0.00013 22.2 9.6 0.00013 22.2 9.6 2.6 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 KFP07171.1 - 0.00047 20.0 11.3 0.00047 20.0 11.3 3.4 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFP07171.1 - 0.00098 18.9 9.1 0.00098 18.9 9.1 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KFP07171.1 - 0.0032 17.3 7.1 0.0059 16.4 7.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 KFP07171.1 - 0.0036 17.4 5.3 0.0036 17.4 5.3 2.6 3 0 0 3 3 2 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KFP07171.1 - 0.013 15.8 8.5 0.071 13.4 8.5 2.3 1 1 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFP07171.1 - 0.025 14.5 8.8 0.025 14.5 8.8 2.9 3 1 0 3 3 2 0 Prokaryotic RING finger family 4 DUF678 PF05077.12 KFP07171.1 - 0.12 12.6 3.4 1.4 9.1 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF678) zf-C3HC4_5 PF17121.5 KFP07171.1 - 0.35 10.8 7.2 1.3 9.0 7.2 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS1595 PF12760.7 KFP07171.1 - 2.7 8.0 13.1 0.74 9.8 0.2 3.0 2 1 1 3 3 3 0 Transposase zinc-ribbon domain zf-RING_6 PF14835.6 KFP07171.1 - 4.2 7.3 13.4 0.042 13.7 4.1 2.4 3 0 0 3 3 3 0 zf-RING of BARD1-type protein DZR PF12773.7 KFP07171.1 - 8.1 6.6 15.6 1.8 8.7 7.2 3.3 3 1 0 3 3 3 0 Double zinc ribbon Ank_2 PF12796.7 KFP07172.1 - 2.1e-29 101.9 3.9 1.2e-12 48.2 0.1 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP07172.1 - 5e-26 90.4 1.9 6e-09 36.0 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP07172.1 - 6e-26 90.5 0.2 5.5e-09 36.4 0.0 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KFP07172.1 - 6.4e-25 86.5 1.5 2.9e-06 27.5 0.0 4.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KFP07172.1 - 9.2e-23 77.9 0.7 5.9e-06 26.2 0.0 5.3 6 0 0 6 6 6 4 Ankyrin repeat DUF5482 PF17579.2 KFP07172.1 - 0.018 14.9 0.1 0.027 14.3 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5482) RNase_P_p30 PF01876.16 KFP07173.1 - 5.4e-61 205.8 0.0 6.3e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 7tm_1 PF00001.21 KFP07174.1 - 1.1e-77 260.9 13.1 1.3e-77 260.7 13.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP07174.1 - 4.3e-09 36.1 12.6 7.3e-09 35.4 12.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP07174.1 - 9.1e-06 25.5 15.2 3.2e-05 23.7 15.2 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP07174.1 - 2.1e-05 24.4 4.9 2.1e-05 24.4 4.9 1.9 2 1 0 3 3 3 1 Olfactory receptor Kinesin PF00225.23 KFP07175.1 - 2.7e-95 319.1 1.6 2.7e-95 319.1 1.6 3.8 2 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KFP07175.1 - 5.2e-19 68.6 0.1 5.2e-19 68.6 0.1 5.3 4 0 0 4 4 4 2 Microtubule binding Cation_ATPase_N PF00690.26 KFP07175.1 - 6.8 6.5 7.1 1.4 8.6 0.9 3.1 3 0 0 3 3 3 0 Cation transporter/ATPase, N-terminus Fumble PF03630.14 KFP07176.1 - 6.5e-121 403.5 0.1 7.5e-121 403.3 0.1 1.0 1 0 0 1 1 1 1 Fumble SpoU_methylase PF00588.19 KFP07176.1 - 0.072 13.3 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 SpoU rRNA Methylase family Yae1_N PF09811.9 KFP07177.1 - 1.8e-14 53.1 47.0 1.8e+04 -11.7 47.0 4.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal MFS_1 PF07690.16 KFP07178.1 - 6.4e-36 124.0 34.3 2.3e-21 76.1 13.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Gate PF07670.14 KFP07178.1 - 0.5 10.7 0.0 0.5 10.7 0.0 3.2 2 2 1 3 3 3 0 Nucleoside recognition Abhydrolase_1 PF00561.20 KFP07179.1 - 4.4e-28 98.6 0.4 5.3e-28 98.4 0.4 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFP07179.1 - 4.8e-09 35.8 0.0 5.5e-06 25.8 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydro_lipase PF04083.16 KFP07179.1 - 2e-05 24.0 0.0 4.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region FSH1 PF03959.13 KFP07179.1 - 0.00018 21.2 0.1 0.0028 17.3 0.1 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Lipase_3 PF01764.25 KFP07179.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) FA_hydroxylase PF04116.13 KFP07180.1 - 1.1e-23 84.0 19.4 1.1e-23 84.0 19.4 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Actin PF00022.19 KFP07181.1 - 7.6e-150 499.0 0.0 2.5e-149 497.3 0.0 1.7 1 1 0 1 1 1 1 Actin USP8_dimer PF08969.11 KFP07182.1 - 2.8e-15 56.5 0.0 4.2e-15 55.9 0.0 1.3 1 1 0 1 1 1 1 USP8 dimerisation domain TPR_8 PF13181.6 KFP07182.1 - 0.012 15.8 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 KFP07183.1 - 7.8e-24 84.7 0.3 1.2e-23 84.1 0.3 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KFP07183.1 - 3.3e-22 77.8 0.1 7.4e-22 76.7 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KFP07183.1 - 0.032 13.5 0.0 6.1 6.0 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Ank_4 PF13637.6 KFP07184.1 - 3.4e-25 88.1 2.2 3.2e-08 33.9 0.0 4.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP07184.1 - 5.4e-25 87.8 1.2 9.2e-12 45.4 0.1 2.5 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP07184.1 - 1.8e-24 85.5 3.3 8.4e-12 45.1 0.1 3.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KFP07184.1 - 1.6e-21 75.7 3.0 5.2e-06 26.7 0.0 5.8 5 1 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 KFP07184.1 - 6.9e-19 66.0 3.2 0.00021 21.5 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Abhydrolase_1 PF00561.20 KFP07185.1 - 3.2e-26 92.5 0.1 6e-26 91.6 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KFP07185.1 - 5.5e-23 80.3 0.1 1.1e-22 79.4 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KFP07185.1 - 0.00085 18.6 0.0 0.77 9.0 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFP07186.1 - 3.6e-29 102.2 0.1 5.8e-29 101.5 0.1 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KFP07186.1 - 1.6e-21 75.7 0.1 3.6e-21 74.5 0.0 1.7 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KFP07186.1 - 7.1e-06 25.5 0.0 0.0051 16.1 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 KFP07186.1 - 0.17 11.4 0.0 0.44 10.1 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family TMEM72 PF16054.5 KFP07187.1 - 4.3e-67 225.3 0.4 5.2e-67 225.1 0.4 1.1 1 0 0 1 1 1 1 Transmembrane protein family 72 Cytochrom_B_N_2 PF13631.6 KFP07187.1 - 0.06 13.4 0.5 0.099 12.6 0.0 1.6 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB IL8 PF00048.20 KFP07188.1 - 1.5e-08 34.7 1.9 1.9e-08 34.3 1.9 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like SNF2_N PF00176.23 KFP07189.1 - 1.1e-74 251.3 0.9 1.6e-73 247.5 0.0 2.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFP07189.1 - 3.9e-17 62.6 0.2 3e-16 59.8 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain TFIIF_beta PF02270.15 KFP07189.1 - 0.0028 17.8 0.0 0.011 15.8 0.0 2.1 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TGF_beta PF00019.20 KFP07190.1 - 9.9e-33 113.2 0.1 1.9e-32 112.3 0.1 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFP07190.1 - 7.2e-25 88.1 0.8 1.7e-24 86.9 0.7 1.5 1 1 0 1 1 1 1 TGF-beta propeptide Homeodomain PF00046.29 KFP07191.1 - 5.4e-25 87.0 5.2 9.3e-25 86.2 5.2 1.4 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 KFP07191.1 - 2e-07 30.6 1.5 2e-07 30.6 1.5 2.4 2 0 0 2 2 2 1 OAR domain Homeobox_KN PF05920.11 KFP07191.1 - 0.0026 17.6 0.4 0.015 15.2 0.1 2.2 2 0 0 2 2 2 1 Homeobox KN domain TP2 PF01254.18 KFP07191.1 - 4 8.0 9.8 1.5 9.4 0.7 2.3 2 0 0 2 2 2 0 Nuclear transition protein 2 V-set PF07686.17 KFP07193.1 - 1.2e-08 35.1 0.1 2.5e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFP07193.1 - 9.3e-06 25.6 0.0 2.2e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFP07193.1 - 2.1e-05 24.6 0.0 9.8e-05 22.5 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP07193.1 - 2.6e-05 24.5 0.1 0.0019 18.5 0.1 2.6 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFP07193.1 - 5.7e-05 23.6 0.0 0.00022 21.8 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin domain Beach PF02138.18 KFP07194.1 - 7.8e-116 386.3 0.5 1.2e-115 385.7 0.1 1.4 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 KFP07194.1 - 9.5e-12 44.9 0.4 2.5e-11 43.5 0.4 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 KFP07194.1 - 3.3e-08 34.1 16.5 1.9e-05 25.3 0.1 5.9 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF4800 PF16057.5 KFP07194.1 - 0.33 10.2 1.4 0.45 9.7 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4800) LRR_8 PF13855.6 KFP07195.1 - 2e-16 59.5 20.5 2.1e-07 30.6 0.4 4.3 2 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KFP07195.1 - 2.3e-15 56.4 45.2 1.2e-06 28.7 0.6 4.9 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP07195.1 - 9.7e-05 22.4 18.5 2.1 9.2 0.3 7.0 5 3 1 6 6 6 1 Leucine Rich Repeat LEDGF PF11467.8 KFP07195.1 - 0.037 13.7 0.0 0.58 9.8 0.0 2.4 2 1 0 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) Ribosomal_S10 PF00338.22 KFP07195.1 - 0.12 12.6 1.0 0.27 11.5 0.2 2.0 2 0 0 2 2 2 0 Ribosomal protein S10p/S20e LRR_6 PF13516.6 KFP07195.1 - 0.46 10.7 0.1 0.46 10.7 0.1 5.3 7 0 0 7 7 7 0 Leucine Rich repeat RIX1 PF08167.12 KFP07196.1 - 0.0021 17.8 2.0 0.0056 16.5 0.0 2.5 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis RhoGAP PF00620.27 KFP07197.1 - 1.9e-48 164.1 0.0 5.6e-48 162.6 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KFP07197.1 - 0.0009 19.7 0.2 0.0057 17.1 0.0 2.3 2 0 0 2 2 2 1 PH domain ATG16 PF08614.11 KFP07197.1 - 0.0011 19.3 6.4 0.0021 18.3 6.4 1.6 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Striatin PF08232.12 KFP07197.1 - 0.007 17.0 7.8 0.02 15.5 7.8 1.7 1 0 0 1 1 1 1 Striatin family RIH_assoc PF08454.11 KFP07197.1 - 0.022 14.6 0.7 0.082 12.8 0.0 2.1 2 0 0 2 2 2 0 RyR and IP3R Homology associated DUF2935 PF11155.8 KFP07197.1 - 0.092 13.1 2.0 8.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Cep57_MT_bd PF06657.13 KFP07197.1 - 0.11 13.0 0.4 0.11 13.0 0.4 2.6 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF1779 PF08680.10 KFP07197.1 - 0.19 11.9 3.0 0.33 11.1 3.0 1.3 1 0 0 1 1 1 0 TATA-box binding CENP-H PF05837.12 KFP07197.1 - 0.86 10.0 9.2 0.86 10.0 7.6 1.9 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Fib_alpha PF08702.10 KFP07197.1 - 1.2 9.4 8.9 9.3 6.4 7.8 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.7 KFP07197.1 - 2.2 8.5 16.6 6 7.0 16.5 1.8 1 1 0 1 1 1 0 Tropomyosin like Syntaxin-6_N PF09177.11 KFP07197.1 - 4.1 8.0 9.5 13 6.4 7.3 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FPP PF05911.11 KFP07197.1 - 6 4.9 22.6 12 3.9 22.6 1.4 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil Pkinase PF00069.25 KFP07198.1 - 2e-63 214.2 0.0 2.5e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP07198.1 - 2.5e-29 102.4 0.0 3.3e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFP07198.1 - 2.6e-07 30.2 0.2 4e-07 29.6 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFP07198.1 - 2.6e-05 23.7 0.1 4.8e-05 22.8 0.1 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFP07198.1 - 0.00045 19.9 0.2 0.00088 18.9 0.2 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KFP07198.1 - 0.0007 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF530 PF04409.12 KFP07198.1 - 0.046 12.1 0.0 0.091 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF530) FTA2 PF13095.6 KFP07198.1 - 0.048 13.3 0.1 0.1 12.2 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 FERM_M PF00373.18 KFP07199.1 - 5.3e-29 101.0 1.8 1.5e-28 99.6 1.8 1.8 1 0 0 1 1 1 1 FERM central domain FERM_C PF09380.10 KFP07199.1 - 4.2e-22 78.3 1.6 6.4e-22 77.8 0.2 2.0 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KFP07199.1 - 9.8e-16 57.5 0.1 6e-15 54.9 0.0 2.3 2 0 0 2 2 2 1 FERM N-terminal domain KIND PF16474.5 KFP07199.1 - 1.6e-08 34.7 0.0 3.6e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Kinase non-catalytic C-lobe domain BCL9 PF11502.8 KFP07199.1 - 0.06 13.2 0.9 0.15 11.9 0.9 1.7 1 0 0 1 1 1 0 B-cell lymphoma 9 protein PDZ_6 PF17820.1 KFP07200.1 - 1e-12 47.7 0.0 1.6e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFP07200.1 - 6e-09 36.1 0.0 9.3e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP07200.1 - 3.9e-05 23.9 0.0 6.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Y_phosphatase PF00102.27 KFP07201.1 - 2.6e-71 239.9 0.0 3.4e-71 239.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFP07201.1 - 0.00054 20.0 0.0 0.042 13.8 0.0 2.2 1 1 0 2 2 2 2 Tyrosine phosphatase family DSPc PF00782.20 KFP07201.1 - 0.0013 18.6 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFP07201.1 - 0.0026 17.9 0.0 0.0058 16.8 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate TGF_beta PF00019.20 KFP07202.1 - 1.8e-29 102.8 0.4 4.6e-29 101.4 0.4 1.7 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGF_beta PF00019.20 KFP07203.1 - 4.8e-29 101.4 0.4 9.6e-29 100.4 0.4 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFP07203.1 - 5.8e-18 65.5 0.8 3.3e-17 63.1 0.8 2.0 1 1 0 1 1 1 1 TGF-beta propeptide Peptidase_S41_N PF11918.8 KFP07204.1 - 5.6e-117 385.6 11.7 3.4e-36 124.3 0.1 4.5 4 0 0 4 4 4 4 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Peptidase_S41 PF03572.18 KFP07204.1 - 7e-98 325.0 0.0 8.8e-25 87.2 0.0 4.2 4 0 0 4 4 4 4 Peptidase family S41 muHD PF10291.9 KFP07204.1 - 0.011 15.2 0.0 1.9 7.9 0.0 2.8 3 0 0 3 3 3 0 Muniscin C-terminal mu homology domain zf-C2H2_4 PF13894.6 KFP07205.1 - 0.0051 17.5 33.9 0.04 14.8 4.6 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger SET PF00856.28 KFP07205.1 - 0.013 15.9 2.8 0.096 13.1 0.1 2.9 2 2 0 2 2 2 0 SET domain zf-C2H2 PF00096.26 KFP07205.1 - 0.11 13.0 29.7 0.6 10.7 6.2 3.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type Zn-C2H2_12 PF18112.1 KFP07205.1 - 0.12 12.8 5.3 0.6 10.6 5.3 2.2 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_2 PF12756.7 KFP07205.1 - 0.31 11.4 17.6 9.4 6.6 0.3 3.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KFP07205.1 - 1.4 9.5 17.5 0.11 13.0 2.7 3.9 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_9 PF16293.5 KFP07205.1 - 3.3 7.6 7.3 0.76 9.7 0.7 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Anth_Ig PF05587.13 KFP07206.1 - 6.2e-42 142.1 2.1 8.2e-42 141.7 1.5 1.5 2 0 0 2 2 2 1 Anthrax receptor extracellular domain VWA PF00092.28 KFP07206.1 - 3.9e-17 63.1 0.0 5.3e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KFP07206.1 - 0.00019 20.9 0.0 0.00029 20.3 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Ant_C PF05586.11 KFP07207.1 - 5.9e-45 151.8 1.3 7.3e-45 151.5 1.3 1.1 1 0 0 1 1 1 1 Anthrax receptor C-terminus region 7tm_1 PF00001.21 KFP07208.1 - 5.5e-49 166.9 27.8 6.4e-49 166.6 27.8 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP07208.1 - 2.7e-05 23.7 26.6 4.5e-05 23.0 26.6 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Git3 PF11710.8 KFP07208.1 - 0.5 10.1 19.3 0.015 15.1 11.0 2.1 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 PSP94 PF05825.11 KFP07209.1 - 2e-20 73.2 10.2 2.1e-20 73.1 10.2 1.0 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) Pacifastin_I PF05375.13 KFP07209.1 - 0.037 13.8 10.8 0.037 13.8 10.8 2.1 2 2 0 2 2 2 0 Pacifastin inhibitor (LCMII) PSP94 PF05825.11 KFP07210.1 - 1.2e-19 70.7 5.3 1.3e-19 70.6 5.3 1.0 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) VWC PF00093.18 KFP07210.1 - 0.0034 17.7 5.9 0.01 16.1 5.9 1.8 1 1 0 1 1 1 1 von Willebrand factor type C domain RINGv PF12906.7 KFP07211.1 - 1.8e-15 56.8 16.6 5.3e-15 55.3 16.6 1.9 1 0 0 1 1 1 1 RING-variant domain DctQ PF04290.12 KFP07211.1 - 0.012 15.5 1.2 0.018 15.0 1.2 1.2 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component S36_mt PF10937.8 KFP07211.1 - 5.4 8.6 10.0 0.56 11.8 0.9 2.7 2 1 0 2 2 2 0 Ribosomal protein S36, mitochondrial p450 PF00067.22 KFP07213.1 - 1.3e-149 498.9 0.1 1.5e-149 498.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 BLOC1_2 PF10046.9 KFP07214.1 - 4e-32 110.4 7.1 5e-32 110.1 7.1 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 ParB PF08775.10 KFP07214.1 - 0.0032 17.9 1.3 0.0052 17.2 1.3 1.3 1 0 0 1 1 1 1 ParB family Pox_Ag35 PF03286.14 KFP07214.1 - 0.024 14.4 0.3 0.03 14.1 0.3 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NPV_P10 PF05531.12 KFP07214.1 - 0.051 14.0 0.2 0.1 13.1 0.2 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 KFP07214.1 - 0.13 12.6 0.2 0.24 11.7 0.1 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) XhlA PF10779.9 KFP07214.1 - 1 9.6 6.2 22 5.4 0.0 3.2 3 1 0 3 3 3 0 Haemolysin XhlA PKD_channel PF08016.12 KFP07215.1 - 2.5e-157 524.0 19.5 2.5e-157 524.0 19.5 1.4 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 KFP07215.1 - 4.3e-27 94.9 28.2 8.4e-27 94.0 28.2 1.5 1 0 0 1 1 1 1 Ion transport protein Fer4_24 PF18109.1 KFP07215.1 - 8.9e-15 54.7 1.0 1.9e-14 53.6 1.0 1.6 1 0 0 1 1 1 1 Ferredoxin I 4Fe-4S cluster domain EF-hand_6 PF13405.6 KFP07215.1 - 0.00081 19.1 1.6 0.66 10.1 0.1 4.1 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 KFP07215.1 - 0.004 16.6 2.6 0.21 11.2 0.1 3.4 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 KFP07215.1 - 0.0086 15.9 0.7 0.063 13.1 0.3 2.6 2 0 0 2 2 2 1 EF-hand domain pair Spc7_N PF15402.6 KFP07215.1 - 0.059 11.6 2.1 0.077 11.2 2.1 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 EF-hand_7 PF13499.6 KFP07215.1 - 0.13 12.7 2.0 0.45 11.0 0.8 2.5 1 1 1 2 2 2 0 EF-hand domain pair PYC_OADA PF02436.18 KFP07215.1 - 0.39 10.4 1.6 0.78 9.5 1.6 1.4 1 0 0 1 1 1 0 Conserved carboxylase domain LETM1 PF07766.13 KFP07215.1 - 0.52 9.6 6.0 0.7 9.2 5.2 1.6 1 1 0 1 1 1 0 LETM1-like protein CwfJ_C_1 PF04677.15 KFP07216.1 - 3.8e-34 117.2 0.0 6.3e-34 116.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 IKBKB_SDD PF18397.1 KFP07217.1 - 6e-136 452.2 10.0 7.9e-136 451.8 10.0 1.1 1 0 0 1 1 1 1 IQBAL scaffold dimerization domain Pkinase PF00069.25 KFP07217.1 - 2.4e-41 141.8 0.0 5.5e-41 140.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP07217.1 - 1.7e-25 89.8 0.0 3.8e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase IKKbetaNEMObind PF12179.8 KFP07217.1 - 3e-12 46.4 1.6 3e-12 46.4 1.6 2.1 2 0 0 2 2 2 1 I-kappa-kinase-beta NEMO binding domain Pkinase_fungal PF17667.1 KFP07217.1 - 1.9e-05 23.7 0.0 3.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFP07217.1 - 0.00038 19.9 0.0 0.00096 18.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP07217.1 - 0.0081 16.1 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family TBK1_ULD PF18396.1 KFP07217.1 - 0.009 15.9 0.0 0.025 14.5 0.0 1.8 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain PNMA PF14893.6 KFP07217.1 - 0.015 14.7 0.6 0.027 13.9 0.6 1.5 1 0 0 1 1 1 0 PNMA YrbL-PhoP_reg PF10707.9 KFP07217.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Band_7 PF01145.25 KFP07218.1 - 3.9e-19 69.4 0.0 3.9e-19 69.4 0.0 1.8 1 1 1 2 2 2 1 SPFH domain / Band 7 family DUF4346 PF14251.6 KFP07218.1 - 0.06 13.4 2.9 0.13 12.4 2.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4346) GCP_C_terminal PF04130.13 KFP07219.1 - 2.7e-88 296.4 15.4 2.7e-88 296.4 15.4 2.3 3 0 0 3 3 3 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KFP07219.1 - 7.6e-78 262.2 1.1 7.6e-78 262.2 1.1 2.9 2 1 0 3 3 3 1 Gamma tubulin complex component N-terminal zf-Tim10_DDP PF02953.15 KFP07219.1 - 0.072 12.7 5.3 0.025 14.2 2.0 1.9 2 0 0 2 2 2 0 Tim10/DDP family zinc finger DUF1635 PF07795.11 KFP07219.1 - 2.6 7.8 6.8 7.3 6.4 6.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) zf-C2H2 PF00096.26 KFP07220.1 - 0.042 14.3 0.4 0.069 13.6 0.4 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP07220.1 - 0.1 13.5 0.4 0.2 12.6 0.4 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger TIG_2 PF18020.1 KFP07220.1 - 0.16 12.6 0.0 0.23 12.1 0.0 1.2 1 0 0 1 1 1 0 TIG domain found in plexin PRAP PF15314.6 KFP07221.1 - 2.9e-17 62.9 15.0 6e-13 49.0 7.2 1.4 1 1 1 2 2 2 2 Proline-rich acidic protein 1, pregnancy-specific uterine DUF3710 PF12502.8 KFP07221.1 - 0.031 13.9 0.0 0.031 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3710) ECH_1 PF00378.20 KFP07222.1 - 3.1e-66 223.2 0.5 3.5e-66 223.1 0.5 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFP07222.1 - 5.3e-31 108.3 0.3 6.2e-31 108.1 0.3 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KFP07222.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S49 MMR_HSR1 PF01926.23 KFP07223.1 - 9.4e-13 48.2 0.0 1.6e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP07223.1 - 3.6e-06 27.0 0.0 0.00011 22.2 0.0 2.2 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KFP07223.1 - 4.3e-06 26.4 0.1 3.9e-05 23.2 0.1 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 KFP07223.1 - 0.00048 20.5 0.0 0.016 15.6 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AIG1 PF04548.16 KFP07223.1 - 0.00053 19.4 0.0 0.0008 18.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.13 KFP07223.1 - 0.0021 17.2 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.23 KFP07223.1 - 0.0029 17.7 1.0 0.31 11.1 0.2 2.3 1 1 1 2 2 2 1 Dynamin family PduV-EutP PF10662.9 KFP07223.1 - 0.0066 16.2 0.0 5.9 6.6 0.0 2.9 4 0 0 4 4 4 2 Ethanolamine utilisation - propanediol utilisation FLgD_tudor PF13861.6 KFP07223.1 - 0.011 16.0 0.1 0.019 15.2 0.1 1.4 1 0 0 1 1 1 0 FlgD Tudor-like domain G-alpha PF00503.20 KFP07223.1 - 0.021 14.0 0.0 0.096 11.8 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit AAA_18 PF13238.6 KFP07223.1 - 0.023 15.3 0.0 0.04 14.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFP07223.1 - 0.026 14.8 0.1 0.28 11.5 0.0 2.5 2 1 1 3 3 3 0 AAA domain GTP_EFTU PF00009.27 KFP07223.1 - 0.034 13.7 0.1 4.9 6.6 0.0 3.0 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Roc PF08477.13 KFP07223.1 - 0.051 13.8 0.0 0.22 11.8 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KFP07223.1 - 0.051 13.0 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Septin PF00735.18 KFP07223.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Septin ATP_bind_1 PF03029.17 KFP07223.1 - 0.12 12.1 0.1 15 5.3 0.0 2.7 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Ras PF00071.22 KFP07223.1 - 0.16 11.5 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Ras family DUF815 PF05673.13 KFP07223.1 - 0.16 11.1 0.0 0.38 9.9 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KFP07223.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Abhydro_lipase PF04083.16 KFP07224.1 - 7.6e-19 67.1 0.0 1.5e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KFP07224.1 - 8.3e-19 68.2 0.1 6e-17 62.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFP07224.1 - 0.00089 18.6 0.0 0.033 13.5 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF900 PF05990.12 KFP07224.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Amino_oxidase PF01593.24 KFP07225.1 - 9.3e-10 38.4 0.0 1.3e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Chitin_bind_4 PF00379.23 KFP07225.1 - 0.07 13.7 0.1 0.18 12.4 0.1 1.7 1 0 0 1 1 1 0 Insect cuticle protein DAO PF01266.24 KFP07225.1 - 0.22 11.1 0.0 0.49 9.9 0.0 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase PTEN_C2 PF10409.9 KFP07227.1 - 2e-45 153.8 2.7 3.1e-45 153.3 2.7 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 KFP07227.1 - 3.2e-08 33.5 0.1 1.9e-07 30.9 0.0 2.0 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP07227.1 - 0.00012 21.7 0.0 0.00032 20.3 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFP07227.1 - 0.0025 17.8 0.0 0.0037 17.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFP07227.1 - 0.0028 17.8 0.0 0.0062 16.7 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate AAA PF00004.29 KFP07228.1 - 1.3e-36 125.9 0.0 3.6e-36 124.5 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFP07228.1 - 3.3e-12 46.0 0.1 7.4e-12 44.9 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KFP07228.1 - 1.2e-05 25.5 1.2 0.091 13.0 0.1 2.9 2 1 1 3 3 3 2 AAA domain RuvB_N PF05496.12 KFP07228.1 - 1.9e-05 24.5 0.0 6.2e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 KFP07228.1 - 5.1e-05 22.8 0.3 0.31 10.4 0.0 3.5 3 1 0 4 4 4 1 Bacterial TniB protein AAA_5 PF07728.14 KFP07228.1 - 0.00011 22.2 0.0 0.001 19.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFP07228.1 - 0.00015 22.2 1.5 0.003 18.0 0.0 2.7 2 1 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 KFP07228.1 - 0.00022 21.3 0.0 0.00043 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KFP07228.1 - 0.00052 20.0 0.3 0.009 15.9 0.0 2.4 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_25 PF13481.6 KFP07228.1 - 0.00053 19.6 0.2 1.3 8.6 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_18 PF13238.6 KFP07228.1 - 0.0041 17.7 0.1 0.033 14.7 0.0 2.5 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 KFP07228.1 - 0.0044 16.4 0.0 0.038 13.4 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 KFP07228.1 - 0.01 15.9 0.0 0.043 13.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KFP07228.1 - 0.012 15.8 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFP07228.1 - 0.013 15.0 0.1 0.072 12.6 0.0 2.2 3 0 0 3 3 3 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KFP07228.1 - 0.02 14.6 0.0 0.06 13.1 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KFP07228.1 - 0.025 14.9 0.0 0.055 13.9 0.0 1.7 1 1 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 KFP07228.1 - 0.027 13.7 0.0 0.071 12.4 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin TIP49 PF06068.13 KFP07228.1 - 0.034 13.4 0.0 0.081 12.1 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_21 PF13304.6 KFP07228.1 - 0.043 13.6 0.2 0.2 11.4 0.1 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 KFP07228.1 - 0.043 13.5 0.1 0.12 12.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain SKI PF01202.22 KFP07228.1 - 0.05 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Shikimate kinase Sigma54_activ_2 PF14532.6 KFP07228.1 - 0.051 13.7 0.1 0.39 10.8 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 KFP07228.1 - 0.064 12.7 0.1 0.97 8.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.6 KFP07228.1 - 0.1 12.8 0.9 3 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KFP07228.1 - 0.14 12.2 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 KFP07228.1 - 0.19 11.1 0.8 0.89 8.8 0.0 2.5 3 1 1 4 4 4 0 KaiC ABC_tran PF00005.27 KFP07228.1 - 0.32 11.5 1.1 1.4 9.5 0.0 2.5 3 2 0 3 3 3 0 ABC transporter AAA_17 PF13207.6 KFP07228.1 - 0.43 11.0 0.0 0.43 11.0 0.0 2.3 3 1 1 4 4 1 0 AAA domain APS_kinase PF01583.20 KFP07229.1 - 2.2e-73 245.4 0.0 3.7e-73 244.6 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.17 KFP07229.1 - 4e-67 225.8 0.0 5.7e-67 225.3 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 KFP07229.1 - 1.2e-51 174.6 0.0 2.1e-51 173.7 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.6 KFP07229.1 - 1.2e-05 25.5 0.0 2.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFP07229.1 - 0.00035 21.1 0.0 0.0017 18.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain PhdYeFM_antitox PF02604.19 KFP07229.1 - 0.083 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system His_Phos_2 PF00328.22 KFP07230.1 - 2.6e-23 83.0 0.4 4.6e-23 82.2 0.4 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF4708 PF15813.5 KFP07230.1 - 0.057 12.6 1.1 0.095 11.8 0.1 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4708) PAP2_C PF14360.6 KFP07231.1 - 5.1e-29 100.6 14.2 5.1e-29 100.6 14.2 2.4 3 0 0 3 3 3 1 PAP2 superfamily C-terminal SAM_3 PF18016.1 KFP07231.1 - 3.2e-07 30.1 0.0 8.5e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PAP2 PF01569.21 KFP07231.1 - 6.1e-06 26.1 10.1 6.1e-06 26.1 10.1 1.8 2 1 0 2 2 2 1 PAP2 superfamily SAM_1 PF00536.30 KFP07231.1 - 0.00033 21.0 0.0 0.00089 19.7 0.0 1.7 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) PAP2_3 PF14378.6 KFP07231.1 - 0.0019 17.9 11.9 0.0019 17.9 11.9 2.2 1 1 1 2 2 2 1 PAP2 superfamily SAM_2 PF07647.17 KFP07231.1 - 0.035 14.2 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFP07231.1 - 0.1 12.6 0.2 0.1 12.6 0.2 2.9 3 1 0 3 3 3 0 Sterile alpha motif (SAM)/Pointed domain RRM_1 PF00076.22 KFP07232.1 - 1e-40 137.3 1.5 5.9e-17 61.3 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DND1_DSRM PF14709.7 KFP07232.1 - 1.6e-24 86.0 0.1 3.3e-24 84.9 0.1 1.6 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 PHM7_cyt PF14703.6 KFP07232.1 - 4.6e-05 23.7 0.4 0.62 10.3 0.0 3.7 3 1 0 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 KFP07232.1 - 6.2e-05 23.0 0.1 0.82 9.8 0.0 3.3 3 1 0 3 3 3 2 RNA recognition motif RRM_5 PF13893.6 KFP07232.1 - 0.00034 20.2 0.1 0.48 10.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KFP07232.1 - 0.0016 18.5 0.1 1.1 9.3 0.0 2.6 2 0 0 2 2 2 2 Limkain b1 RRM_occluded PF16842.5 KFP07232.1 - 0.0064 16.3 0.1 7.2 6.5 0.0 3.1 3 0 0 3 3 3 2 Occluded RNA-recognition motif BRAP2 PF07576.12 KFP07232.1 - 0.012 15.8 0.1 0.13 12.5 0.0 2.4 3 0 0 3 3 3 0 BRCA1-associated protein 2 SET_assoc PF11767.8 KFP07232.1 - 0.031 13.9 0.1 7.7 6.2 0.1 2.4 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated dsrm PF00035.26 KFP07232.1 - 0.051 14.3 0.4 3 8.6 0.1 3.0 2 1 0 2 2 2 0 Double-stranded RNA binding motif HEPN_AbiU2 PF18734.1 KFP07232.1 - 0.11 12.0 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 AbiU2 Nup35_RRM_2 PF14605.6 KFP07232.1 - 0.32 11.0 1.2 37 4.4 0.1 2.8 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif PKcGMP_CC PF16808.5 KFP07233.1 - 1.4e-14 53.7 14.8 1.4e-14 53.7 14.8 1.8 2 0 0 2 2 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Wtap PF17098.5 KFP07233.1 - 0.01 15.8 0.3 0.014 15.4 0.3 1.2 1 0 0 1 1 1 0 WTAP/Mum2p family DUF641 PF04859.12 KFP07233.1 - 0.012 16.0 2.1 0.046 14.1 0.3 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Spc29 PF17082.5 KFP07233.1 - 0.04 13.8 0.2 0.048 13.5 0.2 1.1 1 0 0 1 1 1 0 Spindle Pole Component 29 OmpH PF03938.14 KFP07233.1 - 0.042 14.2 0.7 0.056 13.8 0.7 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IL10 PF00726.17 KFP07233.1 - 0.075 12.5 0.9 1.6 8.2 0.3 2.0 2 0 0 2 2 2 0 Interleukin 10 XLF PF09302.11 KFP07233.1 - 0.13 12.4 1.4 0.15 12.2 0.3 1.5 2 0 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Pkinase PF00069.25 KFP07234.1 - 1.5e-71 240.9 0.0 2.1e-71 240.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP07234.1 - 5.2e-36 124.3 0.0 7.8e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 KFP07234.1 - 6.1e-34 116.0 0.1 5.2e-20 71.3 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Kinase-like PF14531.6 KFP07234.1 - 2.3e-05 23.9 0.0 3.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFP07234.1 - 0.0032 17.4 0.0 0.19 11.6 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_C PF00433.24 KFP07234.1 - 0.03 15.0 3.7 0.072 13.8 3.7 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain Cadherin PF00028.17 KFP07236.1 - 5e-17 62.1 0.0 7.9e-11 42.3 0.0 2.3 2 1 0 2 2 2 2 Cadherin domain Sema PF01403.19 KFP07237.1 - 2.5e-147 491.1 0.0 2.8e-147 491.0 0.0 1.0 1 0 0 1 1 1 1 Sema domain Iso_dh PF00180.20 KFP07238.1 - 4e-58 197.2 0.0 1.9e-50 172.0 0.0 2.0 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase Peptidase_M1_N PF17900.1 KFP07239.1 - 1.1e-37 130.0 0.1 1.4e-28 100.4 0.0 2.3 2 1 1 3 3 3 2 Peptidase M1 N-terminal domain EMP24_GP25L PF01105.24 KFP07240.1 - 4.9e-30 104.8 0.0 5.4e-30 104.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ank_2 PF12796.7 KFP07241.1 - 1.3e-16 60.9 0.9 1.2e-13 51.4 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP07241.1 - 7.2e-14 52.0 0.6 1.6e-05 25.4 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP07241.1 - 1e-12 47.0 1.0 0.0041 17.5 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KFP07241.1 - 1.5e-12 47.4 1.8 5.9e-07 29.6 0.1 3.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KFP07241.1 - 1.7e-12 47.2 5.1 7.9e-06 26.1 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat FMN_dh PF01070.18 KFP07241.1 - 0.034 13.2 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DUF2000 PF09391.10 KFP07241.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2000) RasGEF PF00617.19 KFP07242.1 - 1.4e-56 191.5 0.2 4.5e-56 189.8 0.2 1.9 1 0 0 1 1 1 1 RasGEF domain RhoGEF PF00621.20 KFP07242.1 - 7.8e-33 114.2 1.1 7.8e-33 114.2 1.1 2.3 3 0 0 3 3 2 1 RhoGEF domain RasGEF_N PF00618.20 KFP07242.1 - 5.1e-23 81.3 3.0 6.3e-17 61.7 0.1 3.8 3 1 0 3 3 3 2 RasGEF N-terminal motif PH PF00169.29 KFP07242.1 - 1.1e-15 58.1 0.1 1.2e-14 54.7 0.1 2.6 2 0 0 2 2 2 1 PH domain GOLGA2L5 PF15070.6 KFP07242.1 - 0.00024 19.9 2.4 0.00048 18.9 2.4 1.4 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 IQ PF00612.27 KFP07242.1 - 0.012 15.4 1.6 0.031 14.1 1.6 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif PH_11 PF15413.6 KFP07242.1 - 0.024 15.1 1.9 0.69 10.4 1.9 2.8 1 1 0 1 1 1 0 Pleckstrin homology domain PH_13 PF16652.5 KFP07242.1 - 0.051 13.4 0.1 0.21 11.4 0.1 2.1 1 0 0 1 1 1 0 Pleckstrin homology domain Sec34 PF04136.15 KFP07242.1 - 0.5 10.2 4.4 0.41 10.5 0.2 2.7 2 0 0 2 2 2 0 Sec34-like family DUF641 PF04859.12 KFP07242.1 - 0.51 10.7 6.7 0.1 13.0 1.6 2.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) UPF0147 PF03685.13 KFP07242.1 - 0.74 9.9 2.8 14 5.9 0.0 3.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0147) PI_PP_I PF18363.1 KFP07242.1 - 2 8.7 5.3 9.3 6.5 0.1 4.0 4 0 0 4 4 4 0 Phosphoinositide phosphatase insertion domain Peptidase_C1 PF00112.23 KFP07243.1 - 6.7e-74 248.6 0.5 7.5e-74 248.5 0.5 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KFP07243.1 - 3e-05 23.0 0.8 0.0096 14.7 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Nup160 PF11715.8 KFP07244.1 - 0.0022 16.7 0.0 0.0034 16.1 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 WD40 PF00400.32 KFP07244.1 - 0.17 12.8 15.5 1.8 9.6 0.0 5.8 5 1 0 5 5 5 0 WD domain, G-beta repeat PQQ_3 PF13570.6 KFP07244.1 - 1.8 9.2 3.6 34 5.1 0.2 2.9 3 0 0 3 3 3 0 PQQ-like domain FERM_M PF00373.18 KFP07245.1 - 2.4e-20 73.1 0.0 4.3e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 FERM central domain FERM_C PF09380.10 KFP07245.1 - 1.8e-14 53.9 0.3 3.3e-14 53.0 0.3 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FA PF08736.11 KFP07245.1 - 4.2e-14 52.3 0.1 1.3e-13 50.7 0.1 1.9 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_N PF09379.10 KFP07245.1 - 3.9e-10 39.5 0.2 1.7e-09 37.5 0.1 2.0 2 0 0 2 2 2 1 FERM N-terminal domain YcxB PF14317.6 KFP07245.1 - 0.0052 16.5 0.1 0.012 15.4 0.1 1.6 1 0 0 1 1 1 1 YcxB-like protein TMEM191C PF15194.6 KFP07245.1 - 0.07 13.3 0.5 0.17 12.0 0.5 1.6 1 0 0 1 1 1 0 TMEM191C family Spc7 PF08317.11 KFP07247.1 - 1.7 7.4 28.5 0.14 11.0 10.0 2.7 1 1 2 3 3 3 0 Spc7 kinetochore protein FAM76 PF16046.5 KFP07247.1 - 3.9 6.7 28.8 0.051 12.9 20.3 2.0 2 1 0 2 2 2 0 FAM76 protein NIF PF03031.18 KFP07248.1 - 1.6e-55 187.2 1.0 3.2e-55 186.2 1.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase eIF3_subunit PF08597.10 KFP07249.1 - 3.2e-53 181.1 25.7 3.6e-53 181.0 25.7 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit SR-25 PF10500.9 KFP07249.1 - 8.4 5.9 20.9 3.4 7.2 0.7 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein FeS_assembly_P PF01883.19 KFP07250.1 - 5.4e-07 29.7 0.0 1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein ADAM_spacer1 PF05986.14 KFP07251.1 - 6.1e-33 113.3 0.0 1.2e-32 112.3 0.0 1.5 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Pep_M12B_propep PF01562.19 KFP07251.1 - 1.1e-32 113.2 0.0 2.1e-32 112.3 0.0 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide TSP_1 PF00090.19 KFP07251.1 - 5.2e-27 93.8 140.5 6.7e-09 35.8 7.7 10.9 12 0 0 12 12 11 8 Thrombospondin type 1 domain Reprolysin PF01421.19 KFP07251.1 - 4.4e-26 92.0 0.3 1.3e-25 90.5 0.0 1.9 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 KFP07251.1 - 4.5e-22 78.3 6.9 4.5e-22 78.3 6.9 5.2 5 0 0 5 5 3 2 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 KFP07251.1 - 2.9e-14 53.7 1.3 3.5e-14 53.4 0.1 1.8 2 0 0 2 2 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFP07251.1 - 9e-09 35.9 0.2 1.6e-08 35.1 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFP07251.1 - 1.2e-05 25.3 0.0 2.5e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP07251.1 - 8.7e-05 22.3 0.1 0.00017 21.3 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like RFXA_RFXANK_bdg PF15289.6 KFP07251.1 - 0.058 13.7 1.2 0.14 12.5 1.2 1.6 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain Peptidase_M10 PF00413.24 KFP07251.1 - 0.32 10.8 0.9 0.66 9.8 0.9 1.5 1 1 0 1 1 1 0 Matrixin PLAC PF08686.11 KFP07251.1 - 0.98 10.2 6.2 5.6 7.8 6.2 2.5 1 0 0 1 1 1 0 PLAC (protease and lacunin) domain SAM_decarbox PF01536.16 KFP07251.1 - 2.3 7.1 3.5 0.98 8.4 0.4 1.7 2 0 0 2 2 2 0 Adenosylmethionine decarboxylase MRG PF05712.13 KFP07252.1 - 3.3e-54 183.2 0.7 6.2e-54 182.3 0.7 1.4 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KFP07252.1 - 9.3e-11 41.5 1.6 4.5e-08 32.9 0.0 2.6 2 0 0 2 2 2 2 RNA binding activity-knot of a chromodomain Fmp27_WPPW PF10359.9 KFP07252.1 - 0.027 13.3 0.4 0.034 13.0 0.4 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Ank_2 PF12796.7 KFP07253.1 - 2.1e-28 98.7 0.6 5.3e-10 39.8 0.6 4.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP07253.1 - 7.5e-26 89.9 3.3 4.4e-08 33.2 0.1 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP07253.1 - 1.3e-25 89.4 1.0 9.5e-08 32.5 0.1 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KFP07253.1 - 7.1e-24 83.2 3.7 0.00013 22.3 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 KFP07253.1 - 1.9e-22 76.9 0.1 0.0017 18.7 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Seryl_tRNA_N PF02403.22 KFP07253.1 - 0.00049 20.3 9.7 0.00049 20.3 9.7 12.9 3 2 11 14 14 13 1 Seryl-tRNA synthetase N-terminal domain Phage_GP20 PF06810.11 KFP07253.1 - 0.0016 18.3 3.2 0.0016 18.3 3.2 14.2 4 2 9 14 14 12 2 Phage minor structural protein GP20 GAS PF13851.6 KFP07253.1 - 0.0017 17.8 17.6 0.0017 17.8 17.6 10.9 2 1 9 11 11 11 3 Growth-arrest specific micro-tubule binding DUF4201 PF13870.6 KFP07253.1 - 0.0035 17.1 7.0 0.0035 17.1 7.0 12.5 3 2 7 11 11 11 1 Domain of unknown function (DUF4201) Tup_N PF08581.10 KFP07253.1 - 0.0077 16.5 4.7 0.0077 16.5 4.7 14.4 7 4 5 15 15 14 2 Tup N-terminal 3Beta_HSD PF01073.19 KFP07253.1 - 0.095 11.7 5.0 0.15 11.1 0.3 2.4 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Filament PF00038.21 KFP07253.1 - 3.8 7.0 170.1 0.95 9.0 10.9 8.2 2 1 6 8 8 8 0 Intermediate filament protein TLE_N PF03920.15 KFP07254.1 - 1.3e-51 174.1 7.9 1.9e-51 173.6 7.9 1.2 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.32 KFP07254.1 - 8.5e-17 61.2 19.0 0.015 16.1 1.3 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP07254.1 - 2e-07 31.2 0.0 0.51 10.7 0.0 4.4 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFP07254.1 - 0.0025 17.2 0.0 1.2 8.3 0.0 2.5 2 1 0 2 2 2 2 WD40-like domain Cytochrom_D1 PF02239.16 KFP07254.1 - 0.049 12.1 0.0 2.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Cytochrome D1 heme domain TFIIA PF03153.13 KFP07254.1 - 0.075 13.0 8.6 0.11 12.5 8.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_S18 PF01084.20 KFP07254.1 - 0.17 12.1 0.6 0.31 11.3 0.6 1.4 1 0 0 1 1 1 0 Ribosomal protein S18 Kinesin PF00225.23 KFP07255.1 - 2.9e-102 342.0 1.7 6e-102 341.0 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain MKLP1_Arf_bdg PF16540.5 KFP07255.1 - 5.5e-44 148.6 0.0 1.5e-43 147.2 0.0 1.8 1 0 0 1 1 1 1 Arf6-interacting domain of mitotic kinesin-like protein 1 Microtub_bd PF16796.5 KFP07255.1 - 5.3e-15 55.7 0.3 1.1e-11 44.9 0.0 3.4 3 0 0 3 3 3 2 Microtubule binding ERM PF00769.19 KFP07255.1 - 0.00023 21.1 16.7 0.00023 21.1 16.7 2.3 2 0 0 2 2 2 1 Ezrin/radixin/moesin family ADIP PF11559.8 KFP07255.1 - 0.0082 16.2 12.7 0.0082 16.2 12.7 2.4 2 1 1 3 3 2 1 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 KFP07255.1 - 0.0096 15.9 19.3 0.0096 15.9 19.3 2.7 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Cep57_CLD_2 PF14197.6 KFP07255.1 - 0.077 13.1 6.0 0.45 10.6 6.0 2.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 SpecificRecomb PF10136.9 KFP07255.1 - 0.13 10.6 3.4 0.2 9.9 3.4 1.3 1 0 0 1 1 1 0 Site-specific recombinase Sec8_exocyst PF04048.14 KFP07255.1 - 0.37 10.7 9.0 0.065 13.1 3.3 2.5 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain DUF16 PF01519.16 KFP07255.1 - 2.7 8.5 13.5 1.9 9.0 10.5 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 FapA PF03961.13 KFP07255.1 - 6.3 5.3 14.3 10 4.6 14.3 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 KFP07255.1 - 6.4 6.8 27.2 9.3 6.3 8.4 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 KFP07255.1 - 6.9 4.5 13.2 10 3.9 13.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HlyIII PF03006.20 KFP07256.1 - 5.3e-35 121.2 15.0 8.1e-35 120.6 15.0 1.2 1 0 0 1 1 1 1 Haemolysin-III related C5-epim_C PF06662.13 KFP07258.1 - 9.2e-74 247.0 0.1 1.6e-73 246.3 0.1 1.3 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus NAD_binding_6 PF08030.12 KFP07259.1 - 6.1e-29 101.2 0.0 9.3e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFP07259.1 - 5.2e-23 81.2 0.0 8.8e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KFP07259.1 - 1.2e-17 64.2 1.1 2.4e-17 63.2 1.1 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component EF-hand_1 PF00036.32 KFP07259.1 - 5.4e-11 41.2 0.0 0.00019 20.7 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFP07259.1 - 1.7e-10 39.9 0.0 0.0029 17.4 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KFP07259.1 - 4.9e-09 35.3 0.7 5.5e-05 22.5 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KFP07259.1 - 8.8e-09 35.7 0.0 0.0018 18.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFP07259.1 - 0.0004 20.2 0.0 0.081 12.8 0.0 3.0 2 1 0 2 2 2 1 EF-hand domain pair NAD_binding_1 PF00175.21 KFP07259.1 - 0.0016 19.1 0.0 0.062 13.9 0.0 2.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain LRR_9 PF14580.6 KFP07260.1 - 7.1e-19 68.0 0.1 9e-19 67.6 0.1 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KFP07260.1 - 2.9e-12 46.6 13.0 3.1e-09 36.9 1.4 3.1 1 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP07260.1 - 2.5e-08 33.5 18.7 1.9e-06 27.6 4.6 2.8 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 KFP07260.1 - 3.6e-07 29.7 9.1 0.0032 17.4 0.3 3.8 4 0 0 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.33 KFP07260.1 - 0.00085 19.5 9.0 1.9 9.4 0.2 4.3 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_2 PF07723.13 KFP07260.1 - 0.12 13.0 2.5 12 6.7 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat SDA1 PF05285.12 KFP07260.1 - 0.33 10.3 34.2 0.43 10.0 34.2 1.2 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.12 KFP07260.1 - 0.35 9.3 29.5 0.4 9.1 29.5 1.1 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 KFP07260.1 - 9 4.4 27.0 13 3.9 27.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Integrin_alpha2 PF08441.12 KFP07261.1 - 1.6e-41 142.7 0.1 2.5e-41 142.1 0.1 1.2 1 0 0 1 1 1 1 Integrin alpha VWA PF00092.28 KFP07261.1 - 2.3e-39 135.4 0.1 3.9e-39 134.7 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain FG-GAP PF01839.23 KFP07261.1 - 3e-17 62.4 6.1 4.7e-06 26.6 0.0 4.7 4 0 0 4 4 4 3 FG-GAP repeat VWA_2 PF13519.6 KFP07261.1 - 7.8e-15 55.4 0.0 2.5e-14 53.8 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VCBS PF13517.6 KFP07261.1 - 5.1e-07 30.2 0.2 0.0013 19.3 0.1 3.1 2 0 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 KFP07261.1 - 2.3e-05 24.5 8.8 0.12 12.6 0.0 4.7 5 0 0 5 5 5 2 FG-GAP repeat Cytochrom_B_N_2 PF13631.6 KFP07262.1 - 0.029 14.4 0.0 0.029 14.4 0.0 1.0 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Ank_2 PF12796.7 KFP07263.1 - 2.9e-39 133.5 7.9 4e-19 69.0 0.7 4.9 3 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP07263.1 - 5.4e-35 119.3 6.2 4.9e-12 46.1 0.1 7.2 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 KFP07263.1 - 7.9e-33 111.5 15.2 8.3e-06 26.0 0.1 8.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 KFP07263.1 - 6.5e-32 106.0 11.7 4.1e-05 23.7 0.0 8.7 7 1 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KFP07263.1 - 2.4e-28 97.8 14.5 5.2e-07 29.8 0.5 7.6 3 2 4 7 7 7 6 Ankyrin repeats (many copies) CLN6 PF15156.6 KFP07264.1 - 6.1e-145 481.8 17.4 6.8e-145 481.6 17.4 1.0 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 6 Zn_dep_PLPC PF00882.18 KFP07264.1 - 0.045 13.8 0.0 0.094 12.7 0.0 1.5 1 1 0 1 1 1 0 Zinc dependent phospholipase C CcmD PF04995.14 KFP07264.1 - 0.15 12.2 1.7 16 5.7 1.5 2.3 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Herpes_LMP1 PF05297.11 KFP07264.1 - 0.91 8.6 7.7 0.27 10.4 4.8 1.5 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) EF-hand_7 PF13499.6 KFP07266.1 - 3.7e-18 65.7 0.0 1.3e-08 35.2 0.0 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFP07266.1 - 6.6e-11 41.9 0.4 2.8e-07 30.3 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 KFP07266.1 - 1.2e-10 41.6 0.0 0.00011 22.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 KFP07266.1 - 1.8e-10 39.9 0.3 0.00014 21.5 0.0 4.1 3 1 1 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KFP07266.1 - 7.2e-10 37.7 0.7 0.00036 19.9 0.1 4.3 5 0 0 5 5 5 2 EF hand EF-hand_11 PF08976.11 KFP07266.1 - 0.001 19.9 0.0 0.0032 18.3 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain GPHH PF16905.5 KFP07266.1 - 0.006 16.3 0.0 0.03 14.1 0.0 2.1 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated PINIT PF14324.6 KFP07267.1 - 3.7e-39 134.4 0.2 8.7e-39 133.2 0.2 1.7 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KFP07267.1 - 7.1e-21 73.7 5.0 1.4e-20 72.8 5.0 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KFP07267.1 - 0.00018 21.2 1.5 0.00047 19.9 1.5 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Peptidase_M42 PF05343.14 KFP07267.1 - 0.19 10.7 0.1 0.29 10.1 0.1 1.1 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase zf-C3HC4 PF00097.25 KFP07267.1 - 0.68 9.8 4.9 2.6 8.0 4.9 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MRNIP PF15749.5 KFP07267.1 - 2.5 8.8 8.4 41 4.9 8.4 2.2 1 1 0 1 1 1 0 MRN-interacting protein Pkinase PF00069.25 KFP07268.1 - 6.8e-64 215.8 0.0 8.6e-64 215.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP07268.1 - 1.4e-38 132.6 0.0 1.9e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.24 KFP07268.1 - 6e-13 48.5 0.0 1.3e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 PB1 domain Pkinase_fungal PF17667.1 KFP07268.1 - 6.1e-05 22.0 0.0 7.1e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFP07268.1 - 0.00083 18.7 0.0 0.0018 17.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFP07268.1 - 0.0011 18.0 0.0 0.062 12.2 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KFP07268.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4528 PF15031.6 KFP07269.1 - 9.1e-62 206.7 0.0 1e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4528) Adaptin_binding PF10199.9 KFP07270.1 - 1.1e-18 68.0 2.4 1.5e-18 67.5 2.4 1.2 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Ras PF00071.22 KFP07270.1 - 0.017 14.7 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Ras family MH2 PF03166.14 KFP07271.1 - 1.8e-79 266.3 0.1 2.6e-79 265.8 0.1 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 KFP07271.1 - 4.4e-44 148.9 3.1 9.6e-44 147.8 3.1 1.6 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.9 KFP07271.1 - 0.0086 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 MH2 PF03166.14 KFP07272.1 - 1.3e-56 191.8 0.0 1.4e-56 191.6 0.0 1.0 1 0 0 1 1 1 1 MH2 domain DUF4885 PF16226.5 KFP07273.1 - 0.051 12.6 1.0 0.068 12.2 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4885) DUF2369 PF10179.9 KFP07276.1 - 1.3e-33 115.2 2.5 5.1e-31 106.9 0.5 3.5 3 0 0 3 3 3 2 Uncharacterised conserved protein (DUF2369) fn3 PF00041.21 KFP07276.1 - 2.7e-08 34.0 1.1 0.0086 16.4 0.1 4.4 4 0 0 4 4 4 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFP07276.1 - 0.00022 21.7 0.9 0.13 12.8 0.2 3.4 2 1 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Arc_PepC PF06819.11 KFP07276.1 - 0.084 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain KH_1 PF00013.29 KFP07277.1 - 2.6e-37 126.4 6.2 1.9e-15 56.4 0.4 5.6 6 0 0 6 6 6 3 KH domain SAM_1 PF00536.30 KFP07277.1 - 2.7e-14 53.3 0.1 5.7e-14 52.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP07277.1 - 4.7e-11 42.6 0.1 1.1e-10 41.4 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) KH_10 PF17905.1 KFP07277.1 - 3.5e-09 37.0 0.7 0.0025 18.2 0.2 3.8 3 1 0 3 3 3 2 GLD-3 KH domain 5 KH_2 PF07650.17 KFP07277.1 - 0.00029 20.6 0.2 0.13 12.1 0.2 2.7 2 0 0 2 2 2 2 KH domain SLS PF14611.6 KFP07277.1 - 0.039 13.8 4.6 0.32 10.8 0.4 3.8 2 1 2 4 4 4 0 Mitochondrial inner-membrane-bound regulator IGR PF09597.10 KFP07277.1 - 0.15 12.2 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 IGR protein motif fn3 PF00041.21 KFP07278.1 - 1.9e-07 31.3 0.3 4.9e-07 30.0 0.1 1.8 2 0 0 2 2 2 1 Fibronectin type III domain fn3_4 PF16794.5 KFP07278.1 - 0.01 15.7 0.2 0.019 14.9 0.2 1.4 1 0 0 1 1 1 0 Fibronectin-III type domain PilO PF04350.13 KFP07279.1 - 0.091 12.9 0.3 0.091 12.9 0.3 2.3 3 0 0 3 3 3 0 Pilus assembly protein, PilO Spectrin PF00435.21 KFP07279.1 - 1.9 9.0 7.5 0.27 11.7 2.0 2.5 3 0 0 3 3 3 0 Spectrin repeat RhoGAP PF00620.27 KFP07280.1 - 2.3e-40 137.9 0.2 2.7e-40 137.7 0.2 1.1 1 0 0 1 1 1 1 RhoGAP domain Fanconi_A_N PF15865.5 KFP07280.1 - 0.0034 16.8 0.6 0.004 16.6 0.6 1.1 1 0 0 1 1 1 1 Fanconi anaemia group A protein N terminus MFS_1 PF07690.16 KFP07281.1 - 2.1e-33 115.7 20.3 4e-20 72.1 0.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2046 PF09755.9 KFP07282.1 - 1.9e-120 401.7 49.5 2.2e-120 401.5 49.5 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) ATG16 PF08614.11 KFP07282.1 - 0.055 13.7 39.9 0.59 10.3 21.0 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Death PF00531.22 KFP07283.1 - 3.9e-21 75.0 0.0 6.7e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Death domain DUF2533 PF10752.9 KFP07283.1 - 0.068 13.6 0.5 3.8 8.0 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2533) Ank_2 PF12796.7 KFP07284.1 - 9.3e-142 462.0 45.4 1.2e-15 57.9 0.7 11.6 2 2 9 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.30 KFP07284.1 - 5.1e-130 418.8 63.8 2.7e-06 27.6 0.0 23.2 21 1 2 23 23 23 21 Ankyrin repeat Ank_4 PF13637.6 KFP07284.1 - 1.5e-129 420.9 58.3 7.8e-11 42.3 0.4 17.2 3 2 18 21 21 21 21 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP07284.1 - 4.4e-118 383.8 31.8 2.6e-11 43.5 0.0 15.4 5 5 12 17 17 17 17 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP07284.1 - 9.5e-107 335.9 30.3 0.00013 22.1 0.0 23.6 23 0 0 23 23 23 20 Ankyrin repeat UPA_2 PF17809.1 KFP07284.1 - 1.7e-52 176.7 0.0 6.7e-52 174.8 0.0 2.2 1 0 0 1 1 1 1 UPA domain ZU5 PF00791.20 KFP07284.1 - 1.6e-33 114.9 1.0 5.1e-27 94.1 0.0 3.0 2 0 0 2 2 2 2 ZU5 domain DUF1110 PF06533.12 KFP07284.1 - 1.8 8.5 5.9 0.32 11.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1110) BTB PF00651.31 KFP07285.1 - 7.8e-29 100.1 4.7 5.6e-17 62.0 0.1 3.9 4 0 0 4 4 4 3 BTB/POZ domain Ras PF00071.22 KFP07285.1 - 6.3e-24 84.4 0.0 1.3e-23 83.3 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFP07285.1 - 2.7e-10 40.5 0.0 6.6e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase BACK PF07707.15 KFP07285.1 - 0.33 11.1 3.9 1.5 9.0 0.2 3.1 3 1 1 4 4 4 0 BTB And C-terminal Kelch DUF1154 PF06631.11 KFP07285.1 - 0.38 10.8 2.2 1.3 9.1 2.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) Tmem26 PF09772.9 KFP07286.1 - 7.5e-102 340.6 10.5 8.6e-102 340.4 10.5 1.0 1 0 0 1 1 1 1 Transmembrane protein 26 CLAMP PF14769.6 KFP07287.1 - 8.3e-20 71.1 0.0 1.1e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 Spore_III_AB PF09548.10 KFP07287.1 - 0.026 14.6 0.0 0.032 14.4 0.0 1.3 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Sad1_UNC PF07738.13 KFP07287.1 - 0.076 13.0 0.0 0.23 11.5 0.0 1.7 1 1 0 1 1 1 0 Sad1 / UNC-like C-terminal ARID PF01388.21 KFP07288.1 - 6.6e-17 62.0 0.0 1.6e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Anillin PF08174.11 KFP07289.1 - 8.2e-45 152.7 0.2 1.5e-44 151.8 0.2 1.5 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.29 KFP07289.1 - 1.3e-08 35.3 0.0 3.3e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 PH domain HR1 PF02185.16 KFP07289.1 - 0.003 17.6 1.1 0.0095 16.0 1.1 1.9 1 0 0 1 1 1 1 Hr1 repeat PH_11 PF15413.6 KFP07289.1 - 0.0085 16.5 0.0 0.026 14.9 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain ERM PF00769.19 KFP07290.1 - 0.002 18.0 15.5 0.0026 17.6 15.5 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family RBD-FIP PF09457.10 KFP07290.1 - 0.0087 15.9 2.6 0.047 13.6 2.6 2.2 1 1 0 1 1 1 1 FIP domain Chal_sti_synt_N PF00195.19 KFP07290.1 - 0.016 14.6 1.3 0.036 13.5 0.8 1.7 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain VPS53_C PF16854.5 KFP07290.1 - 0.056 13.3 2.5 0.086 12.7 2.5 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 53 C-terminus FUSC PF04632.12 KFP07290.1 - 0.15 10.6 7.8 0.19 10.2 7.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family PMC2NT PF08066.12 KFP07290.1 - 0.17 12.6 4.0 3.7 8.3 0.0 3.1 1 1 2 3 3 3 0 PMC2NT (NUC016) domain DUF4094 PF13334.6 KFP07290.1 - 0.24 11.8 4.4 4 7.9 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF641 PF04859.12 KFP07290.1 - 0.26 11.6 13.4 0.44 10.9 4.0 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) GrpE PF01025.19 KFP07290.1 - 0.3 10.7 17.6 12 5.6 17.6 2.2 1 1 0 1 1 1 0 GrpE V_ATPase_I PF01496.19 KFP07290.1 - 0.37 8.6 6.0 0.47 8.3 6.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-Q PF13094.6 KFP07290.1 - 0.41 10.8 17.8 0.19 12.0 9.2 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Spc7 PF08317.11 KFP07290.1 - 0.53 9.1 16.5 0.79 8.5 16.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FapA PF03961.13 KFP07290.1 - 0.57 8.7 10.0 0.47 9.0 8.7 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A Nipped-B_C PF12830.7 KFP07290.1 - 0.59 10.0 6.9 1.2 9.1 6.9 1.5 1 1 0 1 1 1 0 Sister chromatid cohesion C-terminus dCache_2 PF08269.11 KFP07290.1 - 0.92 8.6 10.2 2.5 7.2 9.8 1.8 1 1 1 2 2 2 0 Cache domain ATP-synt_E_2 PF08112.11 KFP07290.1 - 0.95 9.8 4.8 8.1 6.8 0.2 2.9 2 1 0 2 2 2 0 ATP synthase epsilon subunit YjbH PF06082.11 KFP07290.1 - 1.1 7.9 4.0 1.3 7.7 4.0 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Exonuc_VII_L PF02601.15 KFP07290.1 - 1.2 8.6 14.8 4 6.9 14.8 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 KFP07290.1 - 1.3 7.8 5.0 2 7.3 5.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein ZapB PF06005.12 KFP07290.1 - 1.4 9.5 20.0 0.28 11.6 4.3 2.8 1 1 2 3 3 3 0 Cell division protein ZapB COG2 PF06148.11 KFP07290.1 - 1.4 9.0 11.2 3.7 7.7 7.4 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ALS2CR8 PF15299.6 KFP07290.1 - 1.9 8.4 8.5 1.4 8.8 2.6 2.3 1 1 1 2 2 2 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 UPF0449 PF15136.6 KFP07290.1 - 2.6 8.6 9.0 8.4 6.9 3.6 2.8 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 DHR10 PF18595.1 KFP07290.1 - 3.2 7.8 24.8 0.5 10.4 15.9 2.4 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain CENP-H PF05837.12 KFP07290.1 - 5.3 7.5 15.2 3.5 8.1 10.5 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) YabA PF06156.13 KFP07290.1 - 5.5 7.7 11.2 5.3 7.7 5.2 2.5 1 1 1 2 2 2 0 Initiation control protein YabA APG6_N PF17675.1 KFP07290.1 - 6.4 7.3 20.9 0.99 9.9 13.0 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region NRBF2 PF08961.10 KFP07291.1 - 1.9e-103 344.2 6.1 3.3e-103 343.4 6.1 1.4 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator NRBF2_MIT PF17169.4 KFP07291.1 - 3.1e-45 152.3 11.1 3.1e-45 152.3 11.1 1.7 2 0 0 2 2 2 1 MIT domain of nuclear receptor-binding factor 2 DivIC PF04977.15 KFP07291.1 - 0.00071 19.3 2.1 0.00071 19.3 2.1 2.0 2 1 0 2 2 2 1 Septum formation initiator MIT PF04212.18 KFP07291.1 - 0.0013 18.7 5.4 0.0036 17.3 5.3 1.9 1 1 0 1 1 1 1 MIT (microtubule interacting and transport) domain YabA PF06156.13 KFP07291.1 - 0.0016 19.1 7.8 0.002 18.7 0.8 2.2 2 0 0 2 2 2 1 Initiation control protein YabA PikAIV_N PF18605.1 KFP07291.1 - 0.0033 17.0 3.9 0.0067 16.0 3.9 1.6 1 0 0 1 1 1 1 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain ZapB PF06005.12 KFP07291.1 - 0.0063 16.9 1.9 0.0063 16.9 1.9 2.4 2 1 0 2 2 2 1 Cell division protein ZapB HALZ PF02183.18 KFP07291.1 - 0.0064 16.7 1.9 0.018 15.3 1.9 1.8 1 0 0 1 1 1 1 Homeobox associated leucine zipper TSC22 PF01166.18 KFP07291.1 - 0.029 14.7 0.5 0.072 13.4 0.5 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF5101 PF17031.5 KFP07291.1 - 0.1 12.7 0.7 0.1 12.7 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5101) JmjC PF02373.22 KFP07292.1 - 2.7e-11 43.9 0.0 1.8e-10 41.3 0.0 2.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-C5HC2 PF02928.16 KFP07292.1 - 0.023 15.1 4.4 0.063 13.7 4.4 1.8 1 0 0 1 1 1 0 C5HC2 zinc finger C1_2 PF03107.16 KFP07292.1 - 0.078 13.3 5.0 0.26 11.6 5.0 1.9 1 0 0 1 1 1 0 C1 domain FYVE PF01363.21 KFP07292.1 - 0.68 10.1 6.5 2.4 8.3 6.5 2.0 1 0 0 1 1 1 0 FYVE zinc finger TB2_DP1_HVA22 PF03134.19 KFP07293.1 - 8.2e-27 93.0 10.0 1.2e-26 92.4 10.0 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Sugar_tr PF00083.24 KFP07294.1 - 5.1e-31 108.0 14.2 6e-31 107.8 14.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP07294.1 - 1.5e-28 99.8 33.4 5.2e-20 71.7 18.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily G2F PF07474.12 KFP07296.1 - 1.5e-63 213.9 0.0 2.3e-63 213.3 0.0 1.3 1 0 0 1 1 1 1 G2F domain Ldl_recept_b PF00058.17 KFP07296.1 - 4.6e-34 116.6 0.3 1.4e-13 51.0 0.0 5.0 5 0 0 5 5 5 3 Low-density lipoprotein receptor repeat class B NIDO PF06119.14 KFP07296.1 - 1.3e-22 80.5 0.0 5.8e-22 78.4 0.0 2.2 2 0 0 2 2 2 1 Nidogen-like EGF_3 PF12947.7 KFP07296.1 - 4e-22 78.1 76.2 2.8e-09 37.0 8.5 5.4 5 0 0 5 5 5 5 EGF domain cEGF PF12662.7 KFP07296.1 - 9.7e-19 67.0 36.6 1.7e-05 24.6 1.0 5.2 4 0 0 4 4 4 4 Complement Clr-like EGF-like EGF_CA PF07645.15 KFP07296.1 - 9.6e-18 64.1 68.5 4.1e-09 36.5 7.4 5.4 5 0 0 5 5 4 4 Calcium-binding EGF domain FXa_inhibition PF14670.6 KFP07296.1 - 7.6e-06 26.1 9.7 7.6e-06 26.1 9.7 5.5 4 1 1 5 5 4 4 Coagulation Factor Xa inhibitory site SGL PF08450.12 KFP07296.1 - 6.9e-05 22.6 0.0 0.0045 16.6 0.0 3.2 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region EGF_MSP1_1 PF12946.7 KFP07296.1 - 0.0019 18.2 50.1 0.93 9.6 6.0 5.4 5 0 0 5 5 5 5 MSP1 EGF domain 1 EGF PF00008.27 KFP07296.1 - 0.0023 18.2 10.0 0.0023 18.2 10.0 5.9 5 0 0 5 5 5 3 EGF-like domain hEGF PF12661.7 KFP07296.1 - 0.022 15.4 5.4 0.022 15.4 5.4 6.1 5 0 0 5 5 5 0 Human growth factor-like EGF RLL PF10036.9 KFP07297.1 - 4.2e-76 256.2 0.5 4.9e-76 256.0 0.5 1.0 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein G-gamma PF00631.22 KFP07298.1 - 3.7e-20 71.7 0.0 4e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 GGL domain FtsX_ECD PF18075.1 KFP07298.1 - 0.016 15.8 0.1 0.019 15.6 0.1 1.0 1 0 0 1 1 1 0 FtsX extracellular domain CP12 PF02672.15 KFP07298.1 - 0.027 15.2 0.2 0.034 14.9 0.2 1.2 1 0 0 1 1 1 0 CP12 domain CHASE8 PF17152.4 KFP07298.1 - 0.089 13.0 0.1 0.097 12.9 0.1 1.1 1 0 0 1 1 1 0 Periplasmic sensor domain FERM_M PF00373.18 KFP07299.1 - 6.8e-17 62.0 1.9 7.5e-17 61.8 0.4 1.8 2 0 0 2 2 2 1 FERM central domain FERM_C PF09380.10 KFP07299.1 - 2.7e-14 53.3 0.0 6.1e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KFP07299.1 - 5e-10 39.2 0.1 1.1e-09 38.0 0.1 1.6 1 0 0 1 1 1 1 FERM N-terminal domain FAM176 PF14851.6 KFP07300.1 - 0.0021 17.7 0.0 0.0029 17.3 0.0 1.1 1 0 0 1 1 1 1 FAM176 family Thioredoxin PF00085.20 KFP07300.1 - 0.011 15.7 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin Pox_Ag35 PF03286.14 KFP07300.1 - 0.1 12.4 2.6 0.12 12.1 2.6 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CcmD PF04995.14 KFP07300.1 - 3.4 7.8 5.3 0.72 10.0 1.6 1.8 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) fn3 PF00041.21 KFP07301.1 - 4.6e-10 39.7 0.0 9.5e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain SPRY PF00622.28 KFP07301.1 - 3.3e-08 33.7 0.0 5.7e-07 29.7 0.0 2.2 1 1 0 1 1 1 1 SPRY domain PRY PF13765.6 KFP07301.1 - 0.0007 19.2 0.0 0.0024 17.4 0.0 2.0 1 1 0 1 1 1 1 SPRY-associated domain ATP-synt_E_2 PF08112.11 KFP07301.1 - 0.19 12.0 0.0 0.42 10.9 0.0 1.5 1 0 0 1 1 1 0 ATP synthase epsilon subunit DUF2203 PF09969.9 KFP07301.1 - 0.2 12.4 1.5 0.35 11.6 1.5 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Phosphorylase PF00343.20 KFP07302.1 - 0 1155.9 0.1 0 1155.7 0.1 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Hydrolase_4 PF12146.8 KFP07303.1 - 4.4e-17 62.1 0.5 1.6e-12 47.2 0.2 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFP07303.1 - 7.1e-15 55.3 0.2 6.7e-12 45.6 0.2 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFP07303.1 - 3.8e-12 47.3 0.6 9.8e-11 42.7 0.6 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KFP07303.1 - 2.4e-06 27.6 0.0 3.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KFP07303.1 - 2.4e-05 24.2 0.4 0.16 11.7 0.0 3.1 2 1 0 3 3 3 1 Phospholipase/Carboxylesterase Thioesterase PF00975.20 KFP07303.1 - 0.00018 21.7 0.0 0.00029 21.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.21 KFP07303.1 - 0.0013 18.3 0.2 0.0041 16.6 0.2 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KFP07303.1 - 0.0043 16.0 0.0 0.0057 15.6 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Cutinase PF01083.22 KFP07303.1 - 0.035 14.1 0.0 0.047 13.6 0.0 1.1 1 0 0 1 1 1 0 Cutinase Abhydrolase_4 PF08386.10 KFP07303.1 - 0.062 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Lipase_3 PF01764.25 KFP07303.1 - 0.071 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) BST2 PF16716.5 KFP07305.1 - 0.00089 19.8 7.7 0.0012 19.4 7.7 1.1 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 UPF0240 PF06784.11 KFP07305.1 - 0.026 14.6 4.3 0.032 14.3 4.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) TMEM237 PF15383.6 KFP07305.1 - 0.044 12.9 0.8 0.042 13.0 0.8 1.0 1 0 0 1 1 1 0 Transmembrane protein 237 ISG65-75 PF11727.8 KFP07305.1 - 0.07 12.4 5.0 0.081 12.2 5.0 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein Baculo_PEP_C PF04513.12 KFP07305.1 - 0.14 12.2 5.7 1.3 9.1 5.7 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus KIAA1430 PF13879.6 KFP07305.1 - 0.27 12.0 8.9 0.65 10.8 8.9 1.7 1 1 0 1 1 1 0 KIAA1430 homologue XhlA PF10779.9 KFP07305.1 - 0.3 11.3 9.8 3.1 8.1 0.6 2.6 2 1 1 3 3 3 0 Haemolysin XhlA DUF1664 PF07889.12 KFP07305.1 - 1.7 8.7 7.1 4.6 7.3 6.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) GTP-bdg_M PF16360.5 KFP07305.1 - 2 9.1 7.7 0.57 10.8 1.1 2.5 1 1 2 3 3 3 0 GTP-binding GTPase Middle Region Occludin_ELL PF07303.13 KFP07305.1 - 5.6 7.7 10.9 8 7.3 6.2 2.0 1 1 1 2 2 2 0 Occludin homology domain YabA PF06156.13 KFP07305.1 - 7.7 7.2 11.1 12 6.6 11.1 1.4 1 1 0 1 1 1 0 Initiation control protein YabA WW PF00397.26 KFP07306.1 - 4.6e-16 58.6 15.8 5e-10 39.3 4.3 3.5 3 0 0 3 3 3 2 WW domain Suppressor_APC PF11414.8 KFP07306.1 - 0.94 9.6 6.3 1.1 9.4 2.8 2.3 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein GBP PF02263.19 KFP07307.1 - 1.3e-94 316.3 0.2 1.7e-94 315.9 0.2 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 KFP07307.1 - 2.5e-06 27.1 0.1 4e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain Tiam_CC_Ex PF18385.1 KFP07307.1 - 0.0058 17.0 0.0 0.021 15.2 0.0 1.9 1 0 0 1 1 1 1 T-lymphoma invasion and metastasis CC-Ex domain CNH PF00780.22 KFP07308.1 - 6.3e-77 258.9 0.7 1.2e-76 258.0 0.7 1.5 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.25 KFP07308.1 - 1.1e-55 188.9 0.0 1.7e-55 188.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP07308.1 - 2e-34 119.1 0.0 3.7e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP07308.1 - 9.8e-05 21.3 0.0 0.00015 20.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFP07308.1 - 0.0084 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 KFP07309.1 - 2.3e-80 269.8 0.0 2.7e-80 269.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP07309.1 - 1.6e-35 122.7 0.0 1.5e-34 119.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFP07309.1 - 5e-05 22.4 0.8 8.4e-05 21.7 0.8 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFP07309.1 - 0.037 14.0 0.2 0.23 11.4 0.1 2.3 1 1 2 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFP07309.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 LRR_4 PF12799.7 KFP07310.1 - 0.12 12.8 2.7 0.39 11.2 0.1 2.9 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) DAO PF01266.24 KFP07311.1 - 3.1e-65 221.1 0.0 4.3e-65 220.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFP07311.1 - 0.0004 20.5 0.1 0.0011 19.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KFP07311.1 - 0.017 14.4 0.1 2.8 7.1 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 KFP07311.1 - 0.033 13.4 0.0 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family RasGEF PF00617.19 KFP07312.1 - 9.8e-50 169.2 0.5 2.1e-49 168.1 0.5 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KFP07312.1 - 2.2e-31 108.2 1.4 1e-30 106.1 0.1 2.6 3 0 0 3 3 3 1 RasGEF N-terminal motif RhoGEF PF00621.20 KFP07312.1 - 1.9e-16 60.8 2.2 1.9e-16 60.8 2.2 2.8 3 1 0 3 3 3 1 RhoGEF domain PH PF00169.29 KFP07312.1 - 3.4e-11 43.6 2.5 8.7e-11 42.3 0.1 2.9 3 0 0 3 3 3 1 PH domain Histone PF00125.24 KFP07312.1 - 4.5e-10 40.0 0.0 1e-09 38.8 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 IQ_SEC7_PH PF16453.5 KFP07312.1 - 0.00017 21.6 0.0 0.00049 20.1 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 KFP07312.1 - 0.0042 16.9 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_10 PF15411.6 KFP07312.1 - 0.017 15.4 0.2 0.057 13.7 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain PH_9 PF15410.6 KFP07312.1 - 0.055 13.8 0.1 0.21 12.0 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain Methyltransf_16 PF10294.9 KFP07313.1 - 4.1e-48 163.4 0.0 4.8e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KFP07313.1 - 1.8e-08 34.4 0.0 2.2e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP07313.1 - 0.00018 21.3 0.0 0.00022 21.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP07313.1 - 0.00087 19.9 0.0 0.0014 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KFP07313.1 - 0.0012 18.5 0.0 0.0017 18.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 KFP07313.1 - 0.002 17.7 0.1 0.0027 17.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KFP07313.1 - 0.0033 18.1 0.0 0.0062 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFP07313.1 - 0.073 12.5 0.0 0.094 12.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KFP07313.1 - 0.084 12.6 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.11 KFP07313.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Mucin-like PF16058.5 KFP07314.1 - 1.9e-09 37.5 45.4 0.00051 20.1 10.0 3.5 1 1 3 4 4 4 4 Mucin-like Arf PF00025.21 KFP07316.1 - 4e-77 257.6 0.0 4.5e-77 257.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFP07316.1 - 3e-15 56.5 0.0 4e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP07316.1 - 1.9e-14 53.6 0.0 2.1e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFP07316.1 - 3e-13 49.6 0.0 3.7e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFP07316.1 - 2e-12 46.9 1.0 4e-08 32.8 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KFP07316.1 - 1.3e-10 41.1 0.0 1.6e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP07316.1 - 9.5e-05 22.5 0.0 0.00014 22.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KFP07316.1 - 0.01 15.1 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase SpoOE-like PF09388.10 KFP07316.1 - 0.021 14.7 1.2 0.038 13.9 1.2 1.4 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein CRISPR_Cas2 PF09827.9 KFP07316.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 CRISPR associated protein Cas2 Ion_trans PF00520.31 KFP07317.1 - 3.8e-223 736.9 100.9 5.3e-70 235.4 13.6 4.2 4 0 0 4 4 4 4 Ion transport protein Na_trans_assoc PF06512.13 KFP07317.1 - 2.9e-31 109.4 5.4 2.9e-31 109.4 5.4 2.1 2 0 0 2 2 2 1 Sodium ion transport-associated PKD_channel PF08016.12 KFP07317.1 - 7.2e-07 28.2 87.2 1.5e-06 27.2 6.8 10.0 7 3 2 10 10 10 8 Polycystin cation channel GPHH PF16905.5 KFP07317.1 - 0.00031 20.4 0.0 0.00065 19.4 0.0 1.6 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated IQ PF00612.27 KFP07317.1 - 0.04 13.7 0.7 0.13 12.1 0.7 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF3337 PF11816.8 KFP07318.1 - 8.4e-50 169.0 0.1 2.9e-49 167.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3337) WD40 PF00400.32 KFP07318.1 - 2.9e-29 100.7 6.6 4.8e-05 24.1 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP07318.1 - 3e-07 30.6 2.5 0.035 14.4 0.2 4.0 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KFP07318.1 - 0.0037 16.1 0.5 0.39 9.4 0.0 3.2 1 1 2 3 3 3 1 Nup133 N terminal like RAWUL PF16207.5 KFP07318.1 - 0.018 15.7 0.0 0.04 14.6 0.0 1.6 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like WD40_like PF17005.5 KFP07318.1 - 0.025 13.9 0.0 0.067 12.5 0.0 1.7 1 0 0 1 1 1 0 WD40-like domain Nup160 PF11715.8 KFP07318.1 - 0.095 11.3 7.7 1.5 7.4 0.2 4.0 2 1 2 4 4 4 0 Nucleoporin Nup120/160 CSRNP_N PF16019.5 KFP07319.1 - 1.9e-103 345.1 8.1 3.1e-103 344.4 8.1 1.3 1 0 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus LIM PF00412.22 KFP07321.1 - 6.3e-08 32.7 10.0 7.1e-08 32.6 10.0 1.0 1 0 0 1 1 1 1 LIM domain DUF2175 PF09943.9 KFP07321.1 - 0.28 11.5 4.3 0.29 11.4 3.5 1.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DUF2685 PF10886.8 KFP07321.1 - 0.84 9.9 6.9 1.7 8.9 7.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2685) Sugar_tr PF00083.24 KFP07322.1 - 2.2e-38 132.3 12.9 2.9e-38 131.9 12.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP07322.1 - 1.1e-36 126.6 35.5 3.7e-32 111.6 21.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFP07322.1 - 1.7e-06 26.9 19.0 5e-05 22.0 2.9 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein TPR_8 PF13181.6 KFP07322.1 - 0.08 13.2 0.0 1.2 9.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.16 KFP07323.1 - 2.3e-18 66.3 39.0 6.6e-12 45.0 18.4 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP07323.1 - 1.1e-16 60.8 23.4 8e-09 34.9 9.8 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 KFP07323.1 - 0.00042 19.0 2.9 0.00042 19.0 2.9 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein Pkinase PF00069.25 KFP07324.1 - 8.1e-61 205.7 0.0 1e-60 205.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP07324.1 - 9.7e-45 152.9 0.0 1.4e-44 152.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 KFP07324.1 - 2.4e-21 75.7 0.0 4.5e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pkinase_fungal PF17667.1 KFP07324.1 - 0.00012 21.0 0.0 0.0002 20.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFP07324.1 - 0.0003 20.2 0.0 0.00046 19.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like TIR_2 PF13676.6 KFP07325.1 - 1.1e-12 48.6 0.0 1.5e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 KFP07325.1 - 1e-10 41.7 0.2 2e-10 40.8 0.2 1.5 1 1 1 2 2 2 1 TIR domain Thiolase_N PF00108.23 KFP07326.1 - 9.2e-87 290.7 1.3 1.3e-86 290.2 1.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFP07326.1 - 1.5e-49 166.7 0.2 3.4e-49 165.6 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KFP07326.1 - 0.00028 20.7 1.2 0.061 13.2 0.1 2.8 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 KFP07326.1 - 0.00052 20.1 0.0 0.0018 18.4 0.0 1.9 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.26 KFP07326.1 - 0.0018 17.9 0.8 0.007 16.0 0.2 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ASH PF15780.5 KFP07327.1 - 6.7e-18 64.7 0.9 0.14 12.4 0.0 9.5 9 1 0 9 9 9 5 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 KFP07327.1 - 4.1e-07 30.2 1.1 0.014 15.7 0.0 4.4 5 0 0 5 5 5 2 Transmembrane protein 131-like PapD-like PF14874.6 KFP07327.1 - 6.2e-05 23.1 0.2 0.28 11.3 0.0 3.7 4 0 0 4 4 4 2 Flagellar-associated PapD-like Motile_Sperm PF00635.26 KFP07327.1 - 0.0017 18.2 0.0 40 4.1 0.0 5.7 6 1 0 6 6 6 0 MSP (Major sperm protein) domain MYCBPAP PF14646.6 KFP07327.1 - 0.011 14.8 1.6 8.7 5.2 0.0 3.8 4 1 0 5 5 5 0 MYCBP-associated protein family PI-PLC-X PF00388.19 KFP07328.1 - 6.1e-69 230.2 0.1 1.4e-68 229.1 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFP07328.1 - 5.2e-44 149.3 0.0 1.1e-43 148.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 KFP07328.1 - 2.5e-35 120.8 1.2 9.3e-35 119.0 0.3 2.5 3 0 0 3 3 3 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 KFP07328.1 - 4.7e-20 71.8 0.2 9.3e-20 70.8 0.2 1.5 1 0 0 1 1 1 1 C2 domain EF-hand_10 PF14788.6 KFP07328.1 - 0.00043 20.1 0.5 0.00092 19.0 0.5 1.6 1 0 0 1 1 1 1 EF hand BDM PF10684.9 KFP07328.1 - 0.15 12.4 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative biofilm-dependent modulation protein Gelsolin PF00626.22 KFP07329.1 - 1.5e-99 326.0 0.0 2.7e-19 68.8 0.0 6.3 6 0 0 6 6 6 6 Gelsolin repeat NIF PF03031.18 KFP07330.1 - 6.6e-53 178.7 0.0 8.6e-53 178.3 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Yae1_N PF09811.9 KFP07331.1 - 1.6e-12 46.9 40.4 1.8e+04 -5.3 40.4 4.1 1 1 0 1 1 1 0 Essential protein Yae1, N terminal HGTP_anticodon PF03129.20 KFP07332.1 - 7.5e-24 83.7 0.1 3.2e-23 81.7 0.0 2.2 2 1 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KFP07332.1 - 2.5e-10 40.6 0.2 9e-10 38.8 0.0 2.2 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 KFP07332.1 - 1.2e-07 31.7 6.3 4.3e-07 30.0 6.3 2.0 1 0 0 1 1 1 1 WHEP-TRS domain OS-D PF03392.13 KFP07332.1 - 0.034 14.2 1.1 0.1 12.7 0.1 2.2 2 0 0 2 2 2 0 Insect pheromone-binding family, A10/OS-D EcoRII-C PF09019.11 KFP07332.1 - 0.062 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 EcoRII C terminal zf-C2H2 PF00096.26 KFP07334.1 - 6.5e-38 127.1 53.2 1.6e-08 34.5 1.2 6.1 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP07334.1 - 5.2e-28 96.2 50.1 1.9e-09 37.5 0.3 7.2 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP07334.1 - 2.5e-24 83.8 47.9 3.8e-05 24.2 0.8 6.1 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFP07334.1 - 7.2e-11 41.7 31.8 0.083 12.7 0.6 6.3 6 0 0 6 6 6 5 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFP07334.1 - 8.3e-11 41.6 37.3 0.0027 17.6 0.3 6.4 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFP07334.1 - 2.5e-08 34.1 22.1 0.0063 16.8 5.0 3.1 1 1 2 3 3 3 3 C2H2-type zinc ribbon zf_UBZ PF18439.1 KFP07334.1 - 1.6e-07 30.8 27.2 0.2 11.3 0.1 6.2 6 0 0 6 6 6 4 Ubiquitin-Binding Zinc Finger C1_4 PF07975.12 KFP07334.1 - 2.6e-07 30.8 17.9 0.0012 19.1 3.3 3.8 1 1 3 4 4 4 3 TFIIH C1-like domain zf-C2H2_jaz PF12171.8 KFP07334.1 - 2.2e-06 27.8 12.6 0.61 10.4 0.1 5.5 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KFP07334.1 - 5.9e-06 26.3 33.7 0.00078 19.5 4.3 5.0 2 1 2 5 5 5 4 Zinc ribbon domain zf-Di19 PF05605.12 KFP07334.1 - 6.9e-06 26.3 10.1 0.0001 22.5 3.1 3.6 2 1 1 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_4 PF13717.6 KFP07334.1 - 3.3e-05 23.7 29.2 2 8.4 0.2 5.9 5 1 0 5 5 5 2 zinc-ribbon domain CpXC PF14353.6 KFP07334.1 - 5.8e-05 23.1 23.0 0.91 9.6 0.1 5.7 1 1 5 6 6 6 1 CpXC protein GAGA PF09237.11 KFP07334.1 - 0.00028 20.6 18.0 0.056 13.3 0.2 5.0 2 2 3 5 5 5 2 GAGA factor HypA PF01155.19 KFP07334.1 - 0.00052 20.0 21.1 0.039 14.0 4.2 3.9 1 1 2 3 3 3 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KFP07334.1 - 0.0007 19.6 28.1 0.0062 16.5 5.4 3.7 1 1 1 2 2 2 1 Double zinc ribbon ADK_lid PF05191.14 KFP07334.1 - 0.00077 19.4 22.7 0.015 15.2 1.1 4.8 3 2 2 5 5 5 2 Adenylate kinase, active site lid zf-C2H2_9 PF16293.5 KFP07334.1 - 0.00094 19.0 5.0 3.7 7.5 0.1 4.1 2 2 2 4 4 4 1 C2H2 type zinc-finger (1 copy) FYDLN_acid PF09538.10 KFP07334.1 - 0.0012 19.4 16.1 2.3 8.9 0.1 5.6 1 1 5 6 6 6 1 Protein of unknown function (FYDLN_acid) zinc_ribbon_15 PF17032.5 KFP07334.1 - 0.0014 19.3 20.8 0.21 12.4 2.6 3.2 1 1 1 3 3 3 2 zinc-ribbon family zf-H2C2_5 PF13909.6 KFP07334.1 - 0.0048 16.6 1.7 0.0048 16.6 1.7 7.6 7 4 0 7 7 5 2 C2H2-type zinc-finger domain DNA_RNApol_7kD PF03604.13 KFP07334.1 - 0.0075 15.9 27.6 0.69 9.6 1.4 6.1 5 1 0 5 5 5 2 DNA directed RNA polymerase, 7 kDa subunit Zn_Tnp_IS1595 PF12760.7 KFP07334.1 - 0.009 16.0 32.4 0.026 14.5 2.7 3.6 3 1 0 3 3 3 2 Transposase zinc-ribbon domain MCM_OB PF17207.3 KFP07334.1 - 0.01 15.7 6.5 0.01 15.7 6.5 3.2 1 1 3 4 4 3 0 MCM OB domain DUF3268 PF11672.8 KFP07334.1 - 0.027 14.8 12.4 0.17 12.2 0.2 3.1 3 0 0 3 3 3 0 zinc-finger-containing domain zinc-ribbons_6 PF07191.12 KFP07334.1 - 0.032 14.2 26.0 1.3e+02 2.7 14.0 4.3 1 1 1 2 2 2 0 zinc-ribbons zf-C2HE PF16278.5 KFP07334.1 - 0.041 14.3 0.7 0.041 14.3 0.7 5.5 1 1 5 6 6 5 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 KFP07334.1 - 0.057 13.3 0.8 0.057 13.3 0.8 6.7 6 0 0 6 6 6 0 zinc-finger of a C2HC-type DUF1610 PF07754.11 KFP07334.1 - 0.062 13.3 0.9 0.062 13.3 0.9 5.3 6 0 0 6 6 6 0 Domain of unknown function (DUF1610) RYDR_ITPR PF01365.21 KFP07334.1 - 0.066 12.6 2.9 4.8 6.6 0.1 2.7 2 1 1 3 3 3 0 RIH domain Zn_ribbon_SprT PF17283.2 KFP07334.1 - 0.075 13.0 34.0 0.19 11.7 2.2 5.5 3 1 2 5 5 5 0 SprT-like zinc ribbon domain LIM PF00412.22 KFP07334.1 - 0.081 13.2 0.9 0.081 13.2 0.9 4.9 2 1 3 5 5 4 0 LIM domain zinc_ribbon_9 PF14369.6 KFP07334.1 - 0.093 13.0 20.1 1.6 9.0 0.0 5.0 5 0 0 5 5 4 0 zinc-ribbon zf-LYAR PF08790.11 KFP07334.1 - 0.19 11.7 18.1 5.1 7.1 0.1 6.0 6 0 0 6 6 6 0 LYAR-type C2HC zinc finger YhfH PF14149.6 KFP07334.1 - 0.26 11.3 32.1 2 8.5 0.1 6.2 5 1 1 6 6 6 0 YhfH-like protein TFIIS_C PF01096.18 KFP07334.1 - 0.45 10.4 31.8 5 7.1 0.1 6.1 6 0 0 6 6 6 0 Transcription factor S-II (TFIIS) zf-ribbon_3 PF13248.6 KFP07334.1 - 0.6 9.6 0.1 0.6 9.6 0.1 6.1 6 0 0 6 6 6 0 zinc-ribbon domain zf-AN1 PF01428.16 KFP07334.1 - 0.65 10.2 0.2 0.65 10.2 0.2 6.3 4 2 2 6 6 5 0 AN1-like Zinc finger zf-UBR PF02207.20 KFP07334.1 - 1.1 9.5 24.0 4.5e+03 -2.1 24.0 3.2 1 1 0 1 1 0 0 Putative zinc finger in N-recognin (UBR box) Terminase_GpA PF05876.12 KFP07334.1 - 1.3 7.5 22.2 0.1 11.2 1.0 3.0 2 1 1 3 3 3 0 Phage terminase large subunit (GpA) Evr1_Alr PF04777.13 KFP07334.1 - 1.4 9.4 19.6 3.5 8.2 0.2 4.9 1 1 5 6 6 6 0 Erv1 / Alr family XPA_N PF01286.18 KFP07334.1 - 1.5 9.0 26.2 6.7 6.9 0.2 6.0 6 0 0 6 6 6 0 XPA protein N-terminal TF_Zn_Ribbon PF08271.12 KFP07334.1 - 1.6 8.3 26.9 3.8 7.1 0.1 5.5 5 1 0 5 5 4 0 TFIIB zinc-binding BolA PF01722.18 KFP07334.1 - 1.7 9.0 11.4 5.4 7.4 0.1 4.0 2 1 2 4 4 4 0 BolA-like protein zf-met PF12874.7 KFP07334.1 - 2.3 8.8 29.2 0.74 10.3 0.7 5.6 5 1 2 7 7 4 0 Zinc-finger of C2H2 type DUF2256 PF10013.9 KFP07334.1 - 3.2 8.0 24.2 2.1 8.5 0.1 5.8 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) PHD PF00628.29 KFP07334.1 - 3.6 7.6 23.4 0.55 10.2 0.5 3.7 3 2 0 3 3 3 0 PHD-finger 7tm_2 PF00002.24 KFP07335.1 - 1.8e-76 256.7 23.5 2.2e-76 256.4 23.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFP07335.1 - 5.3e-19 68.3 3.0 1.2e-18 67.1 3.0 1.6 1 0 0 1 1 1 1 Hormone receptor domain DUF4205 PF13898.6 KFP07337.1 - 9.5e-144 478.6 0.1 1.1e-143 478.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) MIP PF00230.20 KFP07338.1 - 8.2e-80 267.8 10.4 9.6e-80 267.5 10.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein 7tm_2 PF00002.24 KFP07339.1 - 3.1e-84 282.1 17.3 4.3e-84 281.6 17.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFP07339.1 - 2.3e-20 72.6 1.4 5.4e-20 71.5 1.4 1.7 1 0 0 1 1 1 1 Hormone receptor domain Dicty_CAR PF05462.11 KFP07339.1 - 0.0046 16.1 16.4 0.0048 16.1 15.5 1.4 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor RVT_1 PF00078.27 KFP07340.1 - 0.074 12.6 0.0 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) 7tm_2 PF00002.24 KFP07341.1 - 7.4e-87 290.7 11.5 9.9e-87 290.3 11.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFP07341.1 - 5.4e-08 33.0 0.2 5.4e-08 33.0 0.2 2.3 2 0 0 2 2 2 1 Hormone receptor domain Na_Ca_ex PF01699.24 KFP07341.1 - 0.0052 16.8 2.2 0.0052 16.8 2.2 2.2 2 0 0 2 2 2 1 Sodium/calcium exchanger protein Insulin_TMD PF17870.1 KFP07341.1 - 0.037 14.1 0.6 0.15 12.1 0.6 2.1 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment 7tm_2 PF00002.24 KFP07342.1 - 5e-58 196.3 7.7 3.7e-38 131.2 0.3 2.1 1 1 0 2 2 2 2 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFP07342.1 - 4.7e-19 68.4 2.1 4.7e-19 68.4 2.1 1.8 2 0 0 2 2 2 1 Hormone receptor domain DUF2569 PF10754.9 KFP07342.1 - 0.15 12.5 4.4 0.25 11.8 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) Yae1_N PF09811.9 KFP07343.1 - 1.2e-08 34.5 23.9 0.00063 19.4 10.5 3.0 2 1 0 2 2 2 2 Essential protein Yae1, N terminal 7tm_2 PF00002.24 KFP07344.1 - 3.9e-84 281.8 22.7 5.3e-84 281.3 22.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFP07344.1 - 4.9e-22 78.0 3.1 1.3e-21 76.7 3.1 1.8 1 0 0 1 1 1 1 Hormone receptor domain Ac76 PF05814.11 KFP07344.1 - 0.55 10.3 3.4 0.79 9.8 0.1 2.6 2 0 0 2 2 2 0 Orf76 (Ac76) DUF2628 PF10947.8 KFP07344.1 - 7.7 6.9 14.0 1.2 9.5 4.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2628) Longin PF13774.6 KFP07347.1 - 2.3e-16 59.6 0.0 4.4e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain SCAMP PF04144.13 KFP07347.1 - 0.032 14.5 4.5 0.066 13.5 4.5 1.5 1 0 0 1 1 1 0 SCAMP family 7tm_1 PF00001.21 KFP07348.1 - 0.00023 20.6 12.6 0.0062 15.9 12.6 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srbc PF10316.9 KFP07348.1 - 0.0077 15.8 2.0 0.0077 15.8 2.0 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc DUF5090 PF17009.5 KFP07348.1 - 1.6 8.6 7.2 30 4.5 7.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5090) 7tm_1 PF00001.21 KFP07349.1 - 0.00025 20.4 14.7 0.00025 20.4 14.7 2.6 1 1 2 3 3 3 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 KFP07350.1 - 1.5e-05 24.4 21.0 4e-05 23.1 21.0 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2070 PF09843.9 KFP07350.1 - 0.47 8.7 12.1 0.55 8.5 12.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF1772 PF08592.11 KFP07350.1 - 3.9 7.8 8.9 5.2 7.4 6.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) SRTM1 PF15872.5 KFP07350.1 - 4.9 7.4 9.5 4 7.6 4.2 2.5 2 1 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 7tm_1 PF00001.21 KFP07351.1 - 1e-08 34.9 20.9 1.9e-08 33.9 20.9 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2070 PF09843.9 KFP07351.1 - 2.3 6.4 11.7 2.7 6.2 11.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ras PF00071.22 KFP07352.1 - 2.8e-52 176.6 0.0 3.3e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP07352.1 - 5.3e-23 81.5 0.0 8.8e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP07352.1 - 4.9e-07 29.4 0.0 6.4e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP07352.1 - 0.0018 18.4 0.0 0.0029 17.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 KFP07352.1 - 0.0089 16.0 0.1 0.3 11.0 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KFP07352.1 - 0.02 15.3 0.1 0.061 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 KFP07352.1 - 0.039 13.9 0.0 8.4 6.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KFP07352.1 - 0.15 12.6 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KFP07352.1 - 0.23 11.7 0.5 3 8.1 0.4 2.7 1 1 1 2 2 2 0 AAA domain PduV-EutP PF10662.9 KFP07352.1 - 0.24 11.2 0.1 0.74 9.6 0.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PHD_4 PF16866.5 KFP07354.1 - 1.7e-21 76.1 12.0 1.7e-21 76.1 12.0 2.6 2 0 0 2 2 2 1 PHD-finger zf-CXXC PF02008.20 KFP07354.1 - 1.3e-12 47.6 21.5 1.3e-12 47.6 21.5 2.8 2 0 0 2 2 2 1 CXXC zinc finger domain JHD PF17811.1 KFP07354.1 - 1.6e-10 41.4 0.1 3.7e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 Jumonji helical domain F-box PF00646.33 KFP07354.1 - 5.8e-09 35.6 11.6 1.1e-08 34.8 4.9 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KFP07354.1 - 2.9e-08 33.5 6.5 6.5e-08 32.4 6.5 1.6 1 0 0 1 1 1 1 F-box-like JmjC PF02373.22 KFP07354.1 - 3e-05 24.4 4.0 0.00029 21.2 0.7 3.2 2 1 0 2 2 2 1 JmjC domain, hydroxylase LRR_6 PF13516.6 KFP07354.1 - 0.00013 21.7 6.7 4 7.7 0.1 6.0 6 0 0 6 6 6 2 Leucine Rich repeat Cupin_8 PF13621.6 KFP07354.1 - 0.0075 16.0 0.1 0.14 11.8 0.1 2.2 1 1 0 1 1 1 1 Cupin-like domain LRR_4 PF12799.7 KFP07354.1 - 0.078 13.4 9.0 0.092 13.2 1.7 4.1 2 2 2 4 4 4 0 Leucine Rich repeats (2 copies) Cupin_1 PF00190.22 KFP07354.1 - 0.18 11.4 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Cupin Pkinase PF00069.25 KFP07356.1 - 4.8e-63 213.0 0.0 7.8e-62 209.0 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP07356.1 - 4.6e-24 85.1 0.0 7.2e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 KFP07356.1 - 3.8e-17 62.6 3.4 8e-17 61.6 3.4 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain PH PF00169.29 KFP07356.1 - 7.4e-12 45.7 0.1 1.3e-11 44.9 0.1 1.4 1 0 0 1 1 1 1 PH domain HTH_WhiA PF02650.14 KFP07356.1 - 0.00079 19.7 1.4 0.0017 18.7 0.6 1.9 2 0 0 2 2 2 1 WhiA C-terminal HTH domain Kinase-like PF14531.6 KFP07356.1 - 0.004 16.5 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP07356.1 - 0.08 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Gly_acyl_tr_N PF06021.11 KFP07357.1 - 1e-23 84.5 0.0 9.2e-12 45.5 0.0 2.1 2 0 0 2 2 2 2 Aralkyl acyl-CoA:amino acid N-acyltransferase Gly_acyl_tr_C PF08444.10 KFP07357.1 - 4.2e-06 26.9 0.0 6.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Metallophos PF00149.28 KFP07358.1 - 9.9e-41 140.5 0.1 1.1e-40 140.3 0.1 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFP07358.1 - 2.5e-17 63.1 0.6 6.7e-17 61.7 0.4 1.9 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Pkinase PF00069.25 KFP07359.1 - 1.8e-26 93.1 0.0 3.8e-13 49.4 0.0 2.4 3 0 0 3 3 3 2 Protein kinase domain Pkinase_C PF00433.24 KFP07359.1 - 2.4e-09 37.8 3.4 5.6e-09 36.6 3.4 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase_Tyr PF07714.17 KFP07359.1 - 2.1e-07 30.5 0.0 4.2e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Mito_fiss_reg PF05308.11 KFP07359.1 - 0.15 12.1 2.7 0.22 11.6 2.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 KFP07359.1 - 0.85 9.0 6.5 1.2 8.5 6.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF1899 PF08953.11 KFP07360.1 - 3.9e-32 109.9 0.0 6.6e-32 109.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 KFP07360.1 - 1.4e-15 57.4 8.2 1.4e-05 25.7 0.9 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP07360.1 - 2.6e-06 27.6 0.2 0.011 16.0 0.0 3.3 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP07360.1 - 0.0036 17.2 0.0 0.013 15.4 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A EF-hand_1 PF00036.32 KFP07361.1 - 1.5e-24 83.7 10.8 7.1e-08 31.5 0.5 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFP07361.1 - 1.6e-21 76.5 5.3 3.1e-11 43.5 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP07361.1 - 5.6e-19 66.4 5.4 2.6e-07 30.0 0.2 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KFP07361.1 - 7.4e-19 67.4 9.4 3.4e-08 33.2 0.2 3.7 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KFP07361.1 - 7e-16 56.9 16.1 2.6e-06 26.6 0.1 4.9 4 1 1 5 5 5 3 EF hand DIMCO_N PF16844.5 KFP07361.1 - 0.00013 22.2 0.1 0.00023 21.4 0.1 1.6 1 1 0 1 1 1 1 Dinitrogenase iron-molybdenum cofactor, N-terminal Dockerin_1 PF00404.18 KFP07361.1 - 0.00028 21.0 1.5 0.0041 17.3 0.8 2.7 2 1 1 3 3 3 2 Dockerin type I domain TerB PF05099.13 KFP07361.1 - 0.0014 18.6 0.6 1.2 9.1 0.1 2.7 2 1 0 2 2 2 2 Tellurite resistance protein TerB SPARC_Ca_bdg PF10591.9 KFP07361.1 - 0.0041 17.4 0.1 0.64 10.4 0.0 2.3 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFP07361.1 - 0.0068 16.3 3.2 0.32 11.0 0.0 3.0 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand DUF3349 PF11829.8 KFP07361.1 - 0.019 15.7 0.0 8.5 7.2 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) Oxysterol_BP PF01237.18 KFP07362.1 - 8.1e-32 110.5 3.7 8.9e-32 110.3 3.7 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein HSP90 PF00183.18 KFP07362.1 - 0.39 9.5 2.2 0.41 9.5 2.2 1.0 1 0 0 1 1 1 0 Hsp90 protein Syntaxin PF00804.25 KFP07363.1 - 1.9e-29 102.8 8.4 2.9e-29 102.2 8.4 1.2 1 0 0 1 1 1 1 Syntaxin Syntaxin_2 PF14523.6 KFP07363.1 - 1.2e-10 41.7 6.7 2e-10 41.0 6.7 1.4 1 0 0 1 1 1 1 Syntaxin-like protein SNARE PF05739.19 KFP07363.1 - 3.7e-09 36.4 7.3 4.6e-09 36.1 0.7 2.9 3 0 0 3 3 3 1 SNARE domain GyrB_insert PF18053.1 KFP07363.1 - 0.0045 16.9 1.0 0.0045 16.9 1.0 1.5 2 0 0 2 2 1 1 DNA gyrase B subunit insert domain WXG100 PF06013.12 KFP07363.1 - 0.03 14.6 4.4 5.1 7.4 0.0 2.9 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Syntaxin-6_N PF09177.11 KFP07363.1 - 0.031 14.8 3.4 0.031 14.8 3.4 1.8 2 0 0 2 2 1 0 Syntaxin 6, N-terminal Branch PF02485.21 KFP07363.1 - 0.035 13.6 0.2 0.047 13.2 0.2 1.3 1 0 0 1 1 1 0 Core-2/I-Branching enzyme Peptidase_C65 PF10275.9 KFP07363.1 - 0.047 13.1 1.4 0.074 12.5 1.4 1.3 1 0 0 1 1 1 0 Peptidase C65 Otubain DASH_Duo1 PF08651.10 KFP07363.1 - 0.11 12.2 3.3 0.65 9.8 0.1 2.5 2 0 0 2 2 2 0 DASH complex subunit Duo1 AAA_13 PF13166.6 KFP07363.1 - 0.12 11.0 8.0 0.16 10.6 8.0 1.1 1 0 0 1 1 1 0 AAA domain DUF948 PF06103.11 KFP07363.1 - 0.16 12.3 3.7 10 6.4 0.3 3.2 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) RP-C_C PF11800.8 KFP07363.1 - 0.23 11.5 4.6 0.29 11.2 4.0 1.5 1 1 0 1 1 1 0 Replication protein C C-terminal region Fib_alpha PF08702.10 KFP07363.1 - 0.23 11.6 6.1 0.19 11.9 4.2 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FapA PF03961.13 KFP07363.1 - 0.32 9.6 6.8 0.43 9.1 6.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 KFP07363.1 - 0.45 8.4 3.0 0.54 8.1 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.11 KFP07363.1 - 0.97 9.9 9.7 0.57 10.6 0.7 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) COG2 PF06148.11 KFP07363.1 - 1.2 9.2 7.3 7.4 6.7 0.7 2.8 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Uso1_p115_C PF04871.13 KFP07363.1 - 1.5 9.2 9.2 2.1 8.7 3.0 2.4 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Prominin PF05478.11 KFP07363.1 - 1.6 6.6 5.9 4.4 5.1 5.9 1.7 1 1 0 1 1 1 0 Prominin YtxH PF12732.7 KFP07363.1 - 4.2 8.0 5.5 2.9 8.5 1.7 2.6 2 1 0 2 2 2 0 YtxH-like protein APG6_N PF17675.1 KFP07363.1 - 4.6 7.8 9.0 7.7 7.0 9.0 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region XhlA PF10779.9 KFP07363.1 - 8.6 6.6 8.6 45 4.4 0.1 2.7 3 0 0 3 3 2 0 Haemolysin XhlA Ribosomal_L16 PF00252.18 KFP07364.1 - 2e-19 69.9 0.0 2.7e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Cobalamin_bind PF01122.19 KFP07365.1 - 2.9e-21 75.7 0.0 3.7e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic cobalamin-binding protein DUF4430 PF14478.6 KFP07365.1 - 2.8e-10 40.6 0.0 4.1e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4430) Bile_Hydr_Trans PF04775.14 KFP07366.1 - 3.3e-38 130.6 0.0 3.8e-38 130.4 0.0 1.0 1 0 0 1 1 1 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region BAAT_C PF08840.11 KFP07367.1 - 6.1e-53 179.9 0.0 6.7e-53 179.8 0.0 1.0 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 KFP07367.1 - 6.4e-05 22.6 0.0 0.002 17.7 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.13 KFP07367.1 - 0.002 17.8 0.0 0.021 14.5 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Zona_pellucida PF00100.23 KFP07368.1 - 1.5e-50 172.4 0.0 2.2e-50 171.9 0.0 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Trefoil PF00088.18 KFP07368.1 - 0.0013 18.6 7.6 0.0031 17.4 5.3 2.7 3 0 0 3 3 3 1 Trefoil (P-type) domain E_raikovi_mat PF06360.11 KFP07368.1 - 3.6 8.1 6.0 4.7 7.7 0.9 2.7 2 0 0 2 2 2 0 Euplotes raikovi mating pheromone WD40 PF00400.32 KFP07369.1 - 3.5e-33 113.1 12.8 3.9e-08 33.8 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP07369.1 - 1.6e-14 53.9 0.0 0.0024 18.1 0.0 5.0 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP07369.1 - 7.3e-05 21.9 0.7 1.3 7.9 0.0 3.3 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein U-box PF04564.15 KFP07369.1 - 9.1e-05 22.6 0.0 0.00018 21.6 0.0 1.5 1 0 0 1 1 1 1 U-box domain Nup160 PF11715.8 KFP07369.1 - 0.00026 19.8 0.6 0.02 13.5 0.1 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KFP07369.1 - 0.0007 18.2 0.0 0.57 8.7 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.11 KFP07369.1 - 0.00085 19.2 0.0 1.1 9.1 0.0 2.7 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 KFP07369.1 - 0.034 12.9 0.2 1 8.0 0.0 2.1 1 1 0 2 2 2 0 Nup133 N terminal like DUF1830 PF08865.11 KFP07369.1 - 0.051 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) GP3 PF03076.14 KFP07369.1 - 0.1 12.7 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Equine arteritis virus GP3 Frtz PF11768.8 KFP07369.1 - 0.18 10.0 0.0 1 7.6 0.0 2.0 1 1 2 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz E1-E2_ATPase PF00122.20 KFP07371.1 - 6.2e-20 71.5 0.0 1.2e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 KFP07371.1 - 1e-19 70.4 0.4 2e-19 69.5 0.4 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFP07371.1 - 2.7e-17 63.8 0.3 1.1e-13 52.0 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFP07371.1 - 2.8e-06 27.3 0.6 6.9e-06 26.0 0.6 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFP07371.1 - 0.0015 19.0 0.0 0.0029 18.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-H2C2_2 PF13465.6 KFP07373.1 - 7.6e-40 133.6 66.8 2.4e-08 34.0 0.4 9.3 9 1 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFP07373.1 - 1.7e-35 119.5 72.2 1.3e-06 28.5 1.8 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP07373.1 - 6e-25 85.8 67.9 0.00021 21.9 1.6 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFP07373.1 - 5.5e-08 32.6 56.8 0.095 12.7 1.3 8.4 8 0 0 8 8 8 4 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFP07373.1 - 2.9e-06 27.3 28.5 0.0087 16.2 1.4 5.5 3 1 2 5 5 5 4 Zinc ribbon domain C1_4 PF07975.12 KFP07373.1 - 0.00039 20.6 26.8 0.0096 16.1 0.0 5.3 3 2 3 6 6 6 1 TFIIH C1-like domain FYDLN_acid PF09538.10 KFP07373.1 - 0.0047 17.6 17.6 1.7 9.3 1.2 6.0 1 1 4 6 6 6 1 Protein of unknown function (FYDLN_acid) C1_1 PF00130.22 KFP07373.1 - 0.027 14.4 37.7 0.66 9.9 3.4 6.6 4 2 3 7 7 7 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_jaz PF12171.8 KFP07373.1 - 0.03 14.6 41.4 1.2 9.5 0.1 8.0 8 0 0 8 8 8 0 Zinc-finger double-stranded RNA-binding zf-trcl PF13451.6 KFP07373.1 - 0.045 13.6 23.0 9.8 6.2 0.1 6.9 7 0 0 7 7 7 0 Probable zinc-ribbon domain zinc_ribbon_15 PF17032.5 KFP07373.1 - 0.063 14.0 24.2 2 9.2 0.9 4.4 1 1 3 4 4 4 0 zinc-ribbon family Elf1 PF05129.13 KFP07373.1 - 0.21 11.7 0.3 0.21 11.7 0.3 5.2 1 1 4 5 5 5 0 Transcription elongation factor Elf1 like BolA PF01722.18 KFP07373.1 - 0.24 11.7 4.4 5.1 7.4 0.0 3.4 2 1 1 3 3 3 0 BolA-like protein zf-AN1 PF01428.16 KFP07373.1 - 0.26 11.5 46.4 0.53 10.5 4.4 7.6 6 2 2 8 8 7 0 AN1-like Zinc finger DUF2256 PF10013.9 KFP07373.1 - 0.34 11.1 30.3 8.8 6.5 0.4 7.6 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) CpXC PF14353.6 KFP07373.1 - 0.34 10.9 32.1 1.8 8.6 0.1 6.5 3 1 3 6 6 6 0 CpXC protein zf_UBZ PF18439.1 KFP07373.1 - 0.36 10.5 42.1 0.96 9.1 0.1 7.9 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger zf-LYAR PF08790.11 KFP07373.1 - 0.45 10.5 36.2 5.4 7.0 0.3 7.8 8 0 0 8 8 7 0 LYAR-type C2HC zinc finger YhfH PF14149.6 KFP07373.1 - 0.5 10.4 30.2 1.2 9.2 0.2 6.5 7 0 0 7 7 6 0 YhfH-like protein DUF2180 PF09947.9 KFP07373.1 - 0.62 10.1 15.1 0.85 9.6 5.3 4.0 3 2 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) zf-C2H2_11 PF16622.5 KFP07373.1 - 0.81 9.5 41.8 1.7 8.5 0.5 7.1 8 0 0 8 8 8 0 zinc-finger C2H2-type DUF3268 PF11672.8 KFP07373.1 - 1.3 9.4 22.3 0.16 12.3 1.0 4.2 3 2 2 5 5 4 0 zinc-finger-containing domain FYVE PF01363.21 KFP07373.1 - 2.7 8.2 38.5 6.6 6.9 2.8 5.1 1 1 2 3 3 2 0 FYVE zinc finger zf-C2HE PF16278.5 KFP07373.1 - 3.7 8.1 48.1 0.61 10.6 0.2 7.6 2 2 3 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger DNA_RNApol_7kD PF03604.13 KFP07373.1 - 5.3 6.8 29.5 11 5.8 0.1 6.9 7 0 0 7 7 7 0 DNA directed RNA polymerase, 7 kDa subunit Zn-C2H2_12 PF18112.1 KFP07373.1 - 5.5 7.6 12.8 4 8.0 0.5 5.0 5 0 0 5 5 4 0 Autophagy receptor zinc finger-C2H2 domain TFIIS_C PF01096.18 KFP07373.1 - 6.4 6.7 32.6 7.1 6.6 0.3 7.0 7 0 0 7 7 7 0 Transcription factor S-II (TFIIS) zf-ribbon_3 PF13248.6 KFP07373.1 - 6.4 6.3 26.2 6.9 6.2 0.3 6.3 7 0 0 7 7 6 0 zinc-ribbon domain zinc_ribbon_9 PF14369.6 KFP07373.1 - 6.7 7.1 27.3 7.2 7.0 0.0 6.8 7 1 0 7 7 6 0 zinc-ribbon XPA_N PF01286.18 KFP07373.1 - 8.3 6.5 30.0 4.7 7.3 0.2 7.7 8 0 0 8 8 8 0 XPA protein N-terminal PRY PF13765.6 KFP07374.1 - 6.9e-19 67.2 0.0 1.1e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.28 KFP07374.1 - 1.7e-09 37.8 0.0 2.1e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 SPRY domain M-inducer_phosp PF06617.13 KFP07375.1 - 3.9e-57 193.6 9.1 4.4e-57 193.4 7.4 1.8 2 0 0 2 2 2 1 M-phase inducer phosphatase Rhodanese PF00581.20 KFP07375.1 - 6.9e-13 49.1 0.0 1.9e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain MBOAT PF03062.19 KFP07376.1 - 2.6e-29 102.7 13.1 2.6e-29 102.7 13.1 2.1 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family UPF0004 PF00919.20 KFP07377.1 - 3.1e-21 75.3 0.0 6.2e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 KFP07377.1 - 1.5e-19 70.9 0.1 4.8e-19 69.3 0.1 1.8 2 0 0 2 2 2 1 Radical SAM superfamily TRAM PF01938.20 KFP07377.1 - 1.6e-05 24.8 0.0 3.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 TRAM domain RVT_1 PF00078.27 KFP07378.1 - 0.0055 16.3 0.0 0.0087 15.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hormone_1 PF00103.20 KFP07379.1 - 7.9e-72 241.5 0.0 8.9e-72 241.3 0.0 1.0 1 0 0 1 1 1 1 Somatotropin hormone family Neurensin PF14927.6 KFP07382.1 - 8.9e-51 171.1 0.1 1.1e-50 170.8 0.1 1.1 1 0 0 1 1 1 1 Neurensin DUF624 PF04854.14 KFP07382.1 - 0.048 13.8 1.5 0.2 11.8 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF624 DUF2207 PF09972.9 KFP07382.1 - 0.16 10.7 0.1 0.19 10.5 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CrgA PF06781.12 KFP07382.1 - 0.27 11.3 1.3 0.84 9.7 1.3 1.9 1 1 0 1 1 1 0 Cell division protein CrgA DCX PF03607.17 KFP07383.1 - 6e-40 135.2 0.0 1.5e-18 66.6 0.0 2.3 2 0 0 2 2 2 2 Doublecortin CcmB PF03379.13 KFP07384.1 - 0.063 12.8 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 CcmB protein FG-GAP PF01839.23 KFP07385.1 - 5.3e-27 93.6 38.9 1.8e-09 37.5 1.3 6.4 7 1 0 7 7 7 4 FG-GAP repeat VCBS PF13517.6 KFP07385.1 - 4.3e-15 56.1 7.8 3.1e-07 30.9 0.9 3.8 2 1 1 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BBS2_Mid PF14783.6 KFP07385.1 - 0.0049 16.9 0.1 10 6.2 0.0 4.3 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PliI PF16743.5 KFP07385.1 - 0.024 14.4 0.1 19 5.0 0.0 3.9 5 0 0 5 5 5 0 Periplasmic lysozyme inhibitor of I-type lysozyme TcdB_toxin_midN PF12256.8 KFP07385.1 - 0.068 12.5 3.9 1.4 8.2 0.1 3.5 3 1 1 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region C2 PF00168.30 KFP07386.1 - 5.7e-40 135.8 0.0 2.3e-19 69.6 0.1 2.8 2 0 0 2 2 2 2 C2 domain PDZ PF00595.24 KFP07386.1 - 5.6e-10 39.4 0.0 1.3e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP07386.1 - 1.6e-09 37.4 0.0 3.2e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain FYVE_2 PF02318.16 KFP07386.1 - 1.2e-07 32.0 7.0 3.5e-07 30.4 7.0 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger DUF3179 PF11376.8 KFP07386.1 - 0.18 11.2 1.8 0.35 10.2 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3179) zf-piccolo PF05715.13 KFP07386.1 - 9.3 6.5 11.3 25 5.1 11.3 1.8 1 0 0 1 1 1 0 Piccolo Zn-finger Asparaginase_2 PF01112.18 KFP07387.1 - 1.3e-116 389.0 4.8 1.5e-116 388.7 4.8 1.0 1 0 0 1 1 1 1 Asparaginase Glyco_transf_43 PF03360.16 KFP07388.1 - 9.9e-37 126.8 0.1 1.1e-36 126.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 ArfGap PF01412.18 KFP07389.1 - 6e-33 113.4 0.2 6e-33 113.4 0.2 2.0 1 1 1 2 2 2 1 Putative GTPase activating protein for Arf DUF2151 PF10221.9 KFP07389.1 - 0.017 13.8 4.8 0.027 13.1 4.8 1.3 1 0 0 1 1 1 0 Cell cycle and development regulator Afi1 PF07792.12 KFP07389.1 - 0.71 10.4 8.5 0.22 12.0 5.3 1.7 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PcfK PF14058.6 KFP07389.1 - 6.3 7.1 17.4 1.8 8.9 13.6 2.0 2 0 0 2 2 2 0 PcfK-like protein DUF1674 PF07896.12 KFP07390.1 - 2.1e-19 69.7 4.7 2.1e-19 69.7 4.7 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) DUF676 PF05057.14 KFP07391.1 - 6.2e-61 205.7 0.0 1.1e-60 204.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3657 PF12394.8 KFP07391.1 - 2.4e-19 69.6 3.8 4.5e-19 68.8 1.9 2.7 2 0 0 2 2 2 1 Protein FAM135 Palm_thioest PF02089.15 KFP07391.1 - 2e-08 34.4 0.0 5e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 KFP07391.1 - 2.8e-05 24.0 0.0 6.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 KFP07391.1 - 0.001 18.3 0.1 0.002 17.4 0.1 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase LMBR1 PF04791.16 KFP07392.1 - 1.7e-23 83.4 20.7 7.5e-22 77.9 20.3 2.2 1 1 0 1 1 1 1 LMBR1-like membrane protein TMEM132D_C PF15706.5 KFP07392.1 - 0.029 14.2 0.2 0.31 10.8 0.2 2.7 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term 7tm_2 PF00002.24 KFP07393.1 - 4.6e-59 199.7 15.3 7.2e-59 199.0 15.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) TSP_1 PF00090.19 KFP07393.1 - 5.3e-40 135.4 79.2 1.2e-12 47.9 10.7 5.1 5 0 0 5 5 5 4 Thrombospondin type 1 domain GAIN PF16489.5 KFP07393.1 - 6e-36 123.8 0.2 9.5e-36 123.2 0.2 1.3 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain GPS PF01825.21 KFP07393.1 - 4.6e-14 52.7 3.1 4.6e-14 52.7 3.1 2.6 3 0 0 3 3 3 1 GPCR proteolysis site, GPS, motif HRM PF02793.22 KFP07393.1 - 3.4e-07 30.5 0.4 3.4e-07 30.5 0.4 4.1 3 1 0 3 3 3 1 Hormone receptor domain Laminin_G_2 PF02210.24 KFP07395.1 - 1.4e-21 77.3 1.2 4e-17 63.0 0.1 2.1 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 KFP07395.1 - 1.3e-19 70.7 0.2 1.8e-15 57.3 0.0 2.1 2 0 0 2 2 2 2 Laminin G domain EGF PF00008.27 KFP07395.1 - 3.7e-18 65.5 52.5 4.7e-05 23.6 6.2 4.9 5 0 0 5 5 5 4 EGF-like domain hEGF PF12661.7 KFP07395.1 - 7.5e-09 35.9 42.4 0.0028 18.2 4.3 5.8 5 0 0 5 5 5 4 Human growth factor-like EGF EGF_2 PF07974.13 KFP07395.1 - 0.00095 19.5 53.1 0.0058 17.0 9.6 5.1 4 1 0 4 4 4 3 EGF-like domain Laminin_G_2 PF02210.24 KFP07396.1 - 4.4e-37 127.5 0.2 3.4e-17 63.2 0.1 2.1 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 KFP07396.1 - 4.7e-34 117.4 0.0 3.4e-16 59.7 0.0 2.1 2 0 0 2 2 2 2 Laminin G domain EGF PF00008.27 KFP07396.1 - 6.1e-07 29.6 17.6 0.001 19.3 1.1 3.2 2 0 0 2 2 2 2 EGF-like domain Laminin_G_3 PF13385.6 KFP07396.1 - 0.0075 16.4 0.0 2.1 8.5 0.0 2.4 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily EGF_2 PF07974.13 KFP07396.1 - 0.0082 16.5 10.6 0.0082 16.5 10.6 3.0 2 1 0 2 2 2 1 EGF-like domain FXa_inhibition PF14670.6 KFP07396.1 - 0.0087 16.3 19.6 0.069 13.4 5.2 2.7 2 1 0 2 2 2 2 Coagulation Factor Xa inhibitory site hEGF PF12661.7 KFP07396.1 - 0.012 16.2 3.7 0.012 16.2 3.7 4.9 5 0 0 5 5 5 0 Human growth factor-like EGF EGF_3 PF12947.7 KFP07396.1 - 5.4 7.3 18.8 0.87 9.8 2.9 3.0 2 1 0 2 2 2 0 EGF domain TFIIS_M PF07500.14 KFP07397.1 - 1.9e-30 105.6 3.0 1.9e-30 105.6 3.0 3.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 KFP07397.1 - 4.4e-27 94.9 0.0 1e-26 93.6 0.0 1.7 1 0 0 1 1 1 1 SPOC domain PHD PF00628.29 KFP07397.1 - 1.4e-09 37.7 9.9 4.5e-09 36.1 9.9 2.0 1 0 0 1 1 1 1 PHD-finger DHH PF01368.20 KFP07397.1 - 0.053 13.8 0.1 0.2 11.9 0.1 2.0 2 0 0 2 2 2 0 DHH family zf-HC5HC2H_2 PF13832.6 KFP07397.1 - 0.11 12.7 5.1 0.5 10.5 5.1 2.2 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFP07397.1 - 0.33 11.2 5.8 1.1 9.6 3.2 3.1 2 0 0 2 2 2 0 PHD-like zinc-binding domain RAG2_PHD PF13341.6 KFP07397.1 - 0.69 10.0 2.7 0.67 10.1 0.3 2.2 2 0 0 2 2 2 0 RAG2 PHD domain Y_phosphatase PF00102.27 KFP07398.1 - 1.6e-07 31.1 0.0 1.2e-06 28.3 0.0 1.8 1 1 1 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 KFP07398.1 - 2.5e-06 27.3 0.0 3.3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFP07398.1 - 0.039 14.1 0.0 0.054 13.6 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate ALS_ss_C PF10369.9 KFP07398.1 - 0.096 12.9 0.1 0.22 11.7 0.0 1.6 2 0 0 2 2 2 0 Small subunit of acetolactate synthase Peptidase_S13 PF02113.15 KFP07398.1 - 0.12 11.1 0.0 0.14 10.9 0.0 1.0 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Y_phosphatase3 PF13350.6 KFP07398.1 - 0.12 12.3 0.2 0.21 11.6 0.2 1.6 1 1 0 1 1 1 0 Tyrosine phosphatase family Gln-synt_C PF00120.24 KFP07399.1 - 8.7e-75 251.9 0.0 1.7e-74 250.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KFP07399.1 - 3.5e-07 29.9 0.2 5e-06 26.1 0.2 2.5 1 1 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Gln-synt_N_2 PF16952.5 KFP07399.1 - 3.7e-05 23.5 0.0 7.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain DUF4705 PF15788.5 KFP07399.1 - 0.27 11.5 1.8 0.62 10.3 1.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4705) SPARC_Ca_bdg PF10591.9 KFP07400.1 - 5.7e-32 110.4 0.3 1.2e-31 109.3 0.3 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Thyroglobulin_1 PF00086.18 KFP07400.1 - 8e-19 67.1 5.4 8e-19 67.1 5.4 2.7 3 1 0 3 3 3 1 Thyroglobulin type-1 repeat Kazal_2 PF07648.15 KFP07400.1 - 3.2e-12 46.4 12.3 6.3e-12 45.4 7.9 2.6 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFP07400.1 - 4e-06 26.7 6.1 4e-06 26.7 6.1 2.1 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.6 KFP07400.1 - 0.067 13.7 0.1 1.1 9.7 0.1 2.7 2 1 1 3 3 3 0 EF-hand domain pair Torsin PF06309.11 KFP07401.1 - 2.7e-40 137.4 0.9 2.9e-40 137.3 0.9 1.0 1 0 0 1 1 1 1 Torsin DUF815 PF05673.13 KFP07401.1 - 0.062 12.5 0.2 0.068 12.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KFP07401.1 - 0.08 12.6 0.0 0.1 12.3 0.0 1.3 1 1 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.22 KFP07401.1 - 0.088 12.0 0.0 0.098 11.8 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain 7tm_4 PF13853.6 KFP07402.1 - 1.2e-17 64.6 3.0 1.4e-17 64.3 3.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP07402.1 - 0.002 17.5 3.6 0.0029 17.0 3.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4519 PF15012.6 KFP07402.1 - 1.8 8.8 0.0 1.8 8.8 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4519) DUF5560 PF17715.1 KFP07403.1 - 0.036 13.5 1.6 0.073 12.5 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5560) RhoGEF PF00621.20 KFP07404.1 - 3.9e-46 157.6 5.4 3.9e-46 157.6 5.4 1.9 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 KFP07404.1 - 6.2e-11 42.8 0.9 1.4e-10 41.6 0.9 1.6 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.28 KFP07404.1 - 2.2e-10 39.9 2.1 5e-10 38.8 2.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP07404.1 - 5.3e-10 39.0 0.1 9.6e-10 38.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP07404.1 - 1e-07 31.5 0.0 2.3e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH_5 PF15405.6 KFP07404.1 - 0.0027 17.8 0.5 0.065 13.3 0.1 2.6 1 1 1 2 2 2 1 Pleckstrin homology domain Myosin_TH1 PF06017.13 KFP07404.1 - 0.023 14.4 1.4 0.044 13.5 1.4 1.4 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding PH_16 PF17838.1 KFP07404.1 - 0.096 12.5 0.5 0.85 9.5 0.5 2.2 1 1 0 1 1 1 0 PH domain C1q PF00386.21 KFP07405.1 - 2.6e-37 127.9 0.1 3.2e-37 127.6 0.1 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFP07405.1 - 1.2e-29 101.8 82.0 1.8e-10 40.4 24.2 3.7 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) BclA_C PF18573.1 KFP07405.1 - 0.00045 20.1 0.0 0.00067 19.6 0.0 1.2 1 0 0 1 1 1 1 BclA C-terminal domain Peptidase_M3 PF01432.20 KFP07406.1 - 2.8e-144 481.8 0.0 4e-144 481.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 KFP07406.1 - 0.028 14.7 0.3 0.075 13.4 0.0 1.7 2 0 0 2 2 2 0 Effector protein VKG_Carbox PF05090.14 KFP07406.1 - 0.046 12.6 0.1 0.069 12.0 0.1 1.2 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase Spore_III_AB PF09548.10 KFP07406.1 - 0.15 12.2 0.3 0.76 9.9 0.1 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Peptidase_M32 PF02074.15 KFP07406.1 - 0.69 8.6 2.6 1 8.0 0.4 2.3 2 1 1 3 3 3 0 Carboxypeptidase Taq (M32) metallopeptidase RVT_1 PF00078.27 KFP07407.1 - 0.1 12.1 0.0 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) TNFR_c6 PF00020.18 KFP07408.1 - 7.2e-09 35.9 16.3 3e-06 27.5 4.2 5.3 5 1 0 5 5 5 2 TNFR/NGFR cysteine-rich region HEPN PF05168.14 KFP07409.1 - 8.2e-10 38.9 0.1 4e-09 36.6 0.1 2.3 1 0 0 1 1 1 1 HEPN domain DUF4368 PF14287.6 KFP07409.1 - 0.00032 21.0 0.2 0.0015 18.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4368) HATPase_c_3 PF13589.6 KFP07409.1 - 0.00067 19.5 0.1 16 5.3 0.0 5.0 3 2 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DnaJ PF00226.31 KFP07409.1 - 0.0037 17.4 0.3 0.012 15.7 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain Sarcoglycan_1 PF04790.13 KFP07410.1 - 1.1e-81 274.0 0.0 1.3e-81 273.8 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2345 PF10106.9 KFP07410.1 - 0.0055 16.6 0.0 0.024 14.5 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2345) FGF PF00167.18 KFP07411.1 - 1.9e-47 160.4 0.3 2.3e-47 160.2 0.3 1.1 1 0 0 1 1 1 1 Fibroblast growth factor EF-hand_7 PF13499.6 KFP07412.1 - 9.8e-13 48.4 10.8 2.7e-05 24.5 0.1 4.5 4 2 0 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.6 KFP07412.1 - 1.5e-09 37.6 6.7 1.3e-06 28.2 0.1 4.9 4 1 1 5 5 5 2 EF-hand domain pair EF-hand_1 PF00036.32 KFP07412.1 - 1.7e-09 36.6 12.4 0.00019 20.7 0.3 5.6 6 0 0 6 6 6 2 EF hand EF-hand_6 PF13405.6 KFP07412.1 - 3.6e-09 35.8 4.8 0.001 18.9 0.2 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_4 PF12763.7 KFP07412.1 - 0.0044 17.0 3.1 0.16 11.9 0.7 3.4 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 KFP07412.1 - 0.014 14.8 4.0 4.2 7.0 0.2 3.9 3 0 0 3 3 3 0 EF hand DHHC PF01529.20 KFP07413.1 - 3.1e-36 124.5 17.5 3.1e-36 124.5 17.5 2.1 2 0 0 2 2 2 2 DHHC palmitoyltransferase Spt4 PF06093.13 KFP07413.1 - 1.3 9.1 6.3 2.8 8.1 6.3 1.5 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger MRP-63 PF14978.6 KFP07414.1 - 2.2e-36 124.4 4.4 2.4e-36 124.2 4.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosome protein 63 Annexin PF00191.20 KFP07415.1 - 0.012 15.6 0.0 0.034 14.2 0.0 1.7 1 0 0 1 1 1 0 Annexin Dynamitin PF04912.14 KFP07415.1 - 0.03 13.6 0.8 0.051 12.9 0.8 1.3 1 0 0 1 1 1 0 Dynamitin SKA1 PF07160.12 KFP07415.1 - 1.7 8.5 6.8 0.13 12.1 0.7 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 SAP18 PF06487.12 KFP07416.1 - 1.6e-19 70.5 0.0 2.1e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Pkinase PF00069.25 KFP07417.1 - 2.3e-61 207.5 0.1 2.8e-39 135.1 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFP07417.1 - 6.6e-29 101.0 0.1 3.8e-20 72.3 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase UBA PF00627.31 KFP07417.1 - 0.00015 21.6 0.4 0.00028 20.7 0.4 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Pkinase_C PF00433.24 KFP07417.1 - 0.00025 21.7 1.7 0.0008 20.1 1.7 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KFP07417.1 - 0.00054 19.0 1.5 0.0011 18.1 1.5 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFP07417.1 - 0.0039 17.1 0.1 0.047 13.6 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFP07417.1 - 0.01 15.2 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KFP07417.1 - 0.026 13.5 0.1 0.047 12.7 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.6 KFP07417.1 - 0.039 13.3 0.1 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Cadherin_tail PF15974.5 KFP07417.1 - 0.058 13.7 0.2 0.058 13.7 0.2 2.9 2 1 1 3 3 3 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region Pkinase_fungal PF17667.1 KFP07417.1 - 0.18 10.6 1.2 0.99 8.1 0.0 2.3 2 0 0 2 2 2 0 Fungal protein kinase CRM1_C PF08767.11 KFP07418.1 - 0.00052 19.3 1.4 0.00052 19.3 1.4 2.4 2 0 0 2 2 2 1 CRM1 C terminal DUF1804 PF08822.11 KFP07418.1 - 0.77 9.7 2.8 1.2 9.1 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1804) N6-adenineMlase PF10237.9 KFP07419.1 - 9.3e-57 191.3 0.0 1.2e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 KFP07419.1 - 0.00059 19.5 0.0 0.00086 19.0 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 IL17 PF06083.11 KFP07420.1 - 2.7e-23 82.2 0.8 3.7e-23 81.8 0.8 1.2 1 0 0 1 1 1 1 Interleukin-17 FAM221 PF14753.6 KFP07420.1 - 0.044 13.4 0.1 0.054 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein FAM221A/B TPR_2 PF07719.17 KFP07421.1 - 3.3e-38 126.7 13.5 0.00016 21.5 0.1 11.7 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.28 KFP07421.1 - 7e-32 107.9 31.7 2e-06 27.4 0.0 11.3 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_7 PF13176.6 KFP07421.1 - 5.7e-27 91.7 8.4 0.00019 21.2 0.0 10.4 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFP07421.1 - 9.5e-27 93.1 14.7 2.7e-05 24.4 0.1 9.3 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 KFP07421.1 - 3.1e-22 78.8 1.5 7.4e-07 29.6 0.4 6.9 5 2 1 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFP07421.1 - 1.5e-21 74.8 31.2 0.0017 18.4 0.1 12.2 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_6 PF13174.6 KFP07421.1 - 3.8e-20 71.1 13.9 0.021 15.4 0.0 10.5 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFP07421.1 - 5.9e-16 57.9 13.8 2.2e-07 30.4 0.3 7.4 5 1 2 7 7 7 3 TPR repeat TPR_16 PF13432.6 KFP07421.1 - 4.3e-15 56.1 0.1 4.3e-05 24.1 0.0 5.6 6 2 0 6 6 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFP07421.1 - 1.3e-13 50.5 0.0 1.4 9.9 0.0 8.2 5 2 3 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP07421.1 - 2.5e-11 43.7 19.7 1.6e-06 28.2 2.5 6.1 3 2 4 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KFP07421.1 - 9.2e-09 34.9 19.9 0.3 11.0 0.0 9.1 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFP07421.1 - 8.1e-07 29.1 0.0 0.17 12.1 0.0 5.4 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.9 KFP07421.1 - 8.6e-07 28.8 8.0 0.00025 20.8 3.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat-like domain TPR_17 PF13431.6 KFP07421.1 - 3.2e-06 27.1 20.2 0.038 14.4 0.4 8.9 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 KFP07421.1 - 1e-05 24.9 5.1 0.0003 20.1 5.1 3.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP07421.1 - 5.7e-05 22.7 0.4 0.49 9.7 0.0 3.8 3 1 1 4 4 4 2 MalT-like TPR region Sel1 PF08238.12 KFP07421.1 - 0.0012 19.5 14.0 7 7.5 0.1 7.0 8 0 0 8 8 6 0 Sel1 repeat FumaraseC_C PF10415.9 KFP07421.1 - 0.0025 18.2 2.3 0.17 12.3 0.1 3.6 4 0 0 4 4 2 1 Fumarase C C-terminus DUF3808 PF10300.9 KFP07421.1 - 0.0048 15.7 0.2 0.0048 15.7 0.2 2.9 3 1 0 3 3 3 1 Protein of unknown function (DUF3808) Coatomer_E PF04733.14 KFP07421.1 - 0.0079 15.6 4.2 0.066 12.6 0.1 3.5 4 0 0 4 4 4 1 Coatomer epsilon subunit DUF5588 PF17826.1 KFP07421.1 - 0.0099 14.8 0.2 5 5.9 0.0 3.4 3 1 0 3 3 3 1 Family of unknown function (DUF5588) DUF2989 PF11207.8 KFP07421.1 - 0.061 13.1 14.2 2 8.1 0.0 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF2989) TPR_4 PF07721.14 KFP07421.1 - 0.062 14.0 0.0 75 4.4 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 KFP07421.1 - 0.088 13.2 9.4 2 8.8 0.0 5.1 4 1 2 6 6 5 0 Tetratricopeptide repeat Como_LCP PF02247.16 KFP07421.1 - 0.12 10.9 0.8 0.2 10.2 0.8 1.2 1 0 0 1 1 1 0 Large coat protein DUF4810 PF16068.5 KFP07421.1 - 0.13 12.8 5.7 13 6.4 0.0 5.7 6 1 0 6 6 5 0 Domain of unknown function (DUF4810) Fis1_TPR_C PF14853.6 KFP07421.1 - 1.2 9.2 14.4 13 5.9 0.1 6.3 6 1 1 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat Foie-gras_1 PF11817.8 KFP07421.1 - 2.5 7.6 10.1 14 5.2 0.1 4.9 4 2 3 7 7 6 0 Foie gras liver health family 1 SPO22 PF08631.10 KFP07421.1 - 6.1 6.2 9.4 10 5.5 0.1 4.4 5 0 0 5 5 5 0 Meiosis protein SPO22/ZIP4 like 3HCDH_N PF02737.18 KFP07422.1 - 1.4e-47 161.9 0.0 1.8e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KFP07422.1 - 1.2e-14 54.7 0.0 2.5e-14 53.7 0.0 1.6 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DNA_gyraseB PF00204.25 KFP07422.1 - 0.087 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 DNA gyrase B adh_short_C2 PF13561.6 KFP07422.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFP07422.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DASH_Dad4 PF08650.10 KFP07422.1 - 0.17 11.9 0.0 36 4.4 0.0 3.1 3 0 0 3 3 3 0 DASH complex subunit Dad4 Connexin PF00029.19 KFP07423.1 - 6.1e-88 294.5 10.6 6.1e-88 294.5 10.6 2.6 2 1 0 2 2 2 1 Connexin Connexin PF00029.19 KFP07424.1 - 4e-87 291.8 12.1 2.5e-85 286.0 12.1 2.0 1 1 0 1 1 1 1 Connexin Connexin PF00029.19 KFP07425.1 - 1.5e-102 342.3 0.0 1.9e-102 342.0 0.0 1.1 1 0 0 1 1 1 1 Connexin Connexin40_C PF16791.5 KFP07425.1 - 1.6e-06 29.3 6.2 2.4e-06 28.8 0.1 2.7 3 0 0 3 3 3 1 Connexin 40 C-terminal domain zf-FCS PF06467.14 KFP07426.1 - 7.8e-65 214.6 119.2 4.5e-10 39.3 3.3 10.6 10 0 0 10 10 10 10 MYM-type Zinc finger with FCS sequence motif DUF3504 PF12012.8 KFP07426.1 - 3.3e-63 212.5 1.8 1.4e-62 210.5 1.8 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3504) YHS PF04945.13 KFP07426.1 - 0.00025 21.1 1.6 0.0025 17.9 0.3 9.4 9 0 0 9 9 9 3 YHS domain Arc_trans_TRASH PF08394.10 KFP07426.1 - 0.00048 20.4 5.0 0.00048 20.4 5.0 7.9 10 0 0 10 10 10 1 Archaeal TRASH domain Ribosomal_L24e PF01246.20 KFP07426.1 - 0.029 14.6 0.5 0.029 14.6 0.5 6.9 5 1 1 6 6 6 0 Ribosomal protein L24e NosL PF05573.12 KFP07426.1 - 0.039 14.3 4.0 12 6.2 0.0 4.0 3 1 1 4 4 4 0 NosL RRM_1 PF00076.22 KFP07427.1 - 1.6e-33 114.3 0.0 5.5e-16 58.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.11 KFP07427.1 - 1.6e-11 44.2 3.6 8.5e-11 41.9 0.4 2.9 1 1 1 2 2 2 1 NOPS (NUC059) domain RRM_7 PF16367.5 KFP07427.1 - 0.00015 21.8 0.0 0.0017 18.4 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif Zot PF05707.12 KFP07427.1 - 0.55 9.9 3.9 0.98 9.0 3.9 1.6 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) Aldedh PF00171.22 KFP07427.1 - 5 5.5 7.3 7.5 4.9 7.3 1.2 1 0 0 1 1 1 0 Aldehyde dehydrogenase family MRP-S26 PF14943.6 KFP07427.1 - 6.9 6.6 23.8 11 5.9 23.8 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Ank_2 PF12796.7 KFP07428.1 - 2.1e-19 69.9 1.7 9.7e-11 42.1 0.2 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP07428.1 - 2.2e-19 69.2 0.4 1.2e-09 38.2 0.0 3.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP07428.1 - 2e-17 63.3 0.7 1.3e-06 28.9 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP07428.1 - 4.7e-13 48.0 1.6 4.2e-05 23.6 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Chromo PF00385.24 KFP07428.1 - 6.6e-10 38.7 0.8 2.7e-09 36.8 0.8 2.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ank PF00023.30 KFP07428.1 - 6.9e-10 38.9 1.4 0.00032 21.0 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat DUF2852 PF11014.8 KFP07429.1 - 0.14 12.3 15.8 0.13 12.5 8.3 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF2852) Tcp10_C PF07202.13 KFP07430.1 - 2.5e-86 288.1 7.5 2.5e-86 288.1 7.5 1.5 1 1 0 1 1 1 1 T-complex protein 10 C-terminus Plant_vir_prot PF01307.17 KFP07430.1 - 0.015 15.5 0.3 6.1 7.1 0.0 2.6 1 1 2 3 3 3 0 Plant viral movement protein FecR PF04773.13 KFP07430.1 - 0.039 14.6 0.3 8.1 7.1 0.0 3.6 1 1 2 3 3 3 0 FecR protein Acyltransferase PF01553.21 KFP07430.1 - 0.05 13.2 0.0 0.65 9.6 0.0 2.3 1 1 0 1 1 1 0 Acyltransferase TUDOR PF00567.24 KFP07431.1 - 4.2e-88 291.5 7.2 1.7e-20 73.3 0.1 7.7 7 1 0 7 7 7 5 Tudor domain Agenet PF05641.12 KFP07431.1 - 2.7e-09 37.3 1.0 0.25 11.8 0.0 5.2 5 0 0 5 5 5 3 Agenet domain STAS PF01740.21 KFP07431.1 - 0.0015 18.1 0.0 0.0049 16.5 0.0 1.8 1 0 0 1 1 1 1 STAS domain Tudor-knot PF11717.8 KFP07431.1 - 0.0042 17.0 0.0 7 6.6 0.0 3.5 3 0 0 3 3 3 2 RNA binding activity-knot of a chromodomain Tudor_2 PF18104.1 KFP07431.1 - 0.029 14.0 0.2 16 5.3 0.0 3.6 3 0 0 3 3 3 0 Jumonji domain-containing protein 2A Tudor domain DUF4537 PF15057.6 KFP07431.1 - 0.11 12.5 0.0 10 6.1 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4537) KGK PF08872.10 KFP07431.1 - 0.28 11.7 1.5 0.62 10.6 0.5 2.2 2 0 0 2 2 2 0 KGK domain RA PF00788.23 KFP07432.1 - 4.9e-13 49.5 0.0 1.7e-12 47.8 0.0 2.0 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain IQ_SEC7_PH PF16453.5 KFP07432.1 - 0.0034 17.4 0.1 0.023 14.6 0.0 2.2 3 0 0 3 3 3 1 PH domain Ras_bdg_2 PF14847.6 KFP07432.1 - 0.04 14.2 0.0 0.096 13.0 0.0 1.6 1 0 0 1 1 1 0 Ras-binding domain of Byr2 PH_16 PF17838.1 KFP07432.1 - 0.16 11.9 0.7 0.42 10.5 0.2 1.8 2 0 0 2 2 2 0 PH domain RhoGAP PF00620.27 KFP07433.1 - 5e-40 136.8 0.0 6.4e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain Nod1 PF17114.5 KFP07433.1 - 5.5e-07 29.9 0.1 4.2e-06 27.0 0.1 2.0 1 1 0 1 1 1 1 Gef2-related medial cortical node protein Nod1 DUF2183 PF09949.9 KFP07433.1 - 0.12 12.8 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) RHH_7 PF16777.5 KFP07434.1 - 0.007 16.7 0.2 0.029 14.8 0.1 2.1 2 0 0 2 2 2 1 Transcriptional regulator, RHH-like, CopG Fer2 PF00111.27 KFP07435.1 - 1.1e-07 31.7 0.2 1.4e-07 31.3 0.2 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain CTU2 PF10288.9 KFP07435.1 - 0.025 14.8 0.0 0.12 12.6 0.0 1.9 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Zf_RING PF16744.5 KFP07435.1 - 0.042 14.0 0.4 0.5 10.5 0.5 2.0 1 1 1 2 2 2 0 KIAA1045 RING finger zf-CHY PF05495.12 KFP07435.1 - 0.048 14.2 0.4 0.089 13.3 0.4 1.4 1 1 0 1 1 1 0 CHY zinc finger ERM PF00769.19 KFP07436.1 - 7.1e-78 261.8 52.3 7.1e-78 261.8 52.3 2.5 2 1 1 3 3 3 1 Ezrin/radixin/moesin family FERM_C PF09380.10 KFP07436.1 - 3.8e-28 97.7 0.0 1.4e-27 95.9 0.0 2.1 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 KFP07436.1 - 1.1e-27 96.8 1.5 1.1e-27 96.8 1.5 3.5 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.10 KFP07436.1 - 3.3e-15 55.8 0.8 1.7e-14 53.5 0.1 2.5 2 0 0 2 2 2 1 FERM N-terminal domain RNase_Zc3h12a PF11977.8 KFP07437.1 - 2.2e-66 222.5 0.0 2.9e-66 222.0 0.0 1.2 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain UBA_6 PF18039.1 KFP07437.1 - 2.4e-20 72.2 1.9 4.5e-20 71.3 1.9 1.5 1 0 0 1 1 1 1 UBA-like domain zf-CCCH_4 PF18044.1 KFP07437.1 - 0.0001 22.0 7.0 0.00018 21.3 7.0 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Omega-toxin PF06357.11 KFP07437.1 - 0.011 15.5 4.8 0.022 14.6 4.8 1.3 1 0 0 1 1 1 0 Omega-atracotoxin PRORP PF16953.5 KFP07437.1 - 0.069 12.7 0.0 0.092 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein-only RNase P zf-CCCH_2 PF14608.6 KFP07437.1 - 1.2 9.8 9.6 2.6 8.6 9.6 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 KFP07437.1 - 1.2 9.1 8.3 9.3 6.3 8.3 2.1 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CD34_antigen PF06365.12 KFP07438.1 - 0.0029 17.2 0.1 0.0037 16.9 0.1 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family DUF3169 PF11368.8 KFP07438.1 - 0.0057 16.2 0.0 0.007 15.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) TMEM154 PF15102.6 KFP07438.1 - 0.0087 16.0 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family LapA_dom PF06305.11 KFP07438.1 - 0.014 15.2 0.2 0.024 14.5 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain TssO PF17561.2 KFP07438.1 - 0.018 15.1 0.5 0.024 14.7 0.5 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO DUF2663 PF10864.8 KFP07438.1 - 0.021 15.2 0.2 0.028 14.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) COX2_TM PF02790.15 KFP07438.1 - 0.025 14.7 0.3 0.043 14.0 0.3 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain 7tm_1 PF00001.21 KFP07438.1 - 0.033 13.5 0.0 0.033 13.5 0.0 1.0 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) OAD_gamma PF04277.13 KFP07438.1 - 0.053 14.1 0.1 0.11 13.1 0.0 1.5 2 0 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain DUF3328 PF11807.8 KFP07438.1 - 0.065 13.0 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) ATP-synt_8 PF00895.20 KFP07438.1 - 0.088 13.3 0.6 0.16 12.4 0.6 1.4 1 0 0 1 1 1 0 ATP synthase protein 8 EphA2_TM PF14575.6 KFP07438.1 - 0.12 13.3 0.0 0.19 12.7 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4834 PF16118.5 KFP07438.1 - 0.12 13.3 0.1 0.18 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Brr6_like_C_C PF10104.9 KFP07438.1 - 1.1 9.0 5.5 1.5 8.6 4.4 1.7 1 1 1 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain DEAD PF00270.29 KFP07439.1 - 1.9e-47 161.3 1.8 8.4e-47 159.2 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP07439.1 - 8.4e-25 87.3 0.1 9.7e-24 83.9 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFP07439.1 - 8.7e-18 64.3 0.3 2.1e-17 63.1 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KFP07439.1 - 9.4e-11 42.0 0.0 9.4e-11 42.0 0.0 3.2 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Glyco_transf_90 PF05686.12 KFP07440.1 - 9.1e-86 288.2 0.3 1.2e-85 287.9 0.3 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Filamin PF00630.19 KFP07440.1 - 0.0028 18.4 0.0 0.0054 17.5 0.0 1.5 1 0 0 1 1 1 1 Filamin/ABP280 repeat Glyco_trans_1_2 PF13524.6 KFP07440.1 - 0.068 13.6 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 NPAT_C PF15712.5 KFP07441.1 - 5.9e-279 927.5 41.5 5.9e-279 927.5 41.5 3.5 3 1 1 4 4 4 1 NPAT C terminus Thiolase_N PF00108.23 KFP07442.1 - 1e-93 313.5 2.6 1.4e-93 313.1 2.6 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFP07442.1 - 9.2e-47 157.7 2.5 3.7e-46 155.8 0.4 2.4 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFP07442.1 - 1.5e-05 24.7 6.5 2.8e-05 23.8 2.7 2.6 2 1 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Cullin PF00888.22 KFP07443.1 - 3.8e-191 636.9 17.6 5.3e-191 636.4 17.6 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KFP07443.1 - 6.2e-19 67.8 6.7 2.2e-18 66.1 6.7 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain Stork_head PF10264.9 KFP07443.1 - 0.041 14.0 2.0 0.082 13.1 0.8 2.1 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain Ras PF00071.22 KFP07444.1 - 1.3e-29 102.9 0.0 1.6e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP07444.1 - 7.5e-06 26.2 0.0 1.4e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase CENP-M PF11111.8 KFP07444.1 - 0.082 12.1 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Centromere protein M (CENP-M) SLC35F PF06027.12 KFP07445.1 - 2.3e-136 454.2 29.1 2.7e-136 454.0 29.1 1.0 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 KFP07445.1 - 2.1e-11 44.1 34.7 4.3e-06 27.0 17.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 KFP07445.1 - 6.4e-10 38.5 9.4 6.4e-10 38.5 9.4 1.9 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like ELMO_CED12 PF04727.13 KFP07446.1 - 3.1e-46 157.7 0.1 4.9e-46 157.1 0.1 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family 2OG-FeII_Oxy_2 PF13532.6 KFP07447.1 - 2e-20 73.8 0.0 4.9e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.12 KFP07447.1 - 6.5e-15 55.6 0.1 5.2e-14 52.7 0.1 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP07447.1 - 1.3e-12 48.2 0.2 5.4e-12 46.3 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain RRM_1 PF00076.22 KFP07447.1 - 2e-08 33.9 0.0 4.5e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_31 PF13847.6 KFP07447.1 - 1.5e-05 24.9 0.1 3.2e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KFP07447.1 - 2.5e-05 24.2 0.0 4.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_23 PF13489.6 KFP07447.1 - 7.1e-05 22.7 0.0 0.00029 20.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain DUF1891 PF09004.10 KFP07447.1 - 0.00012 21.6 0.1 0.00045 19.8 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1891) Methyltransf_12 PF08242.12 KFP07447.1 - 0.00015 22.4 0.0 0.0005 20.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFP07447.1 - 0.003 16.9 0.0 0.0073 15.7 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 KFP07447.1 - 0.039 13.5 0.1 0.072 12.7 0.1 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW 2OG-FeII_Oxy PF03171.20 KFP07447.1 - 0.04 14.4 0.0 0.099 13.1 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Methyltransf_18 PF12847.7 KFP07447.1 - 0.12 12.3 0.1 6.5 6.7 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain VOMI PF03762.17 KFP07449.1 - 5.9e-51 173.0 0.9 6.8e-51 172.8 0.9 1.0 1 0 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) Guanylate_cyc PF00211.20 KFP07450.1 - 3.4e-62 209.3 0.0 5.6e-62 208.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KFP07450.1 - 1.6e-50 171.6 2.9 8.3e-49 166.0 2.9 2.3 1 1 0 1 1 1 1 Heme NO binding associated HNOB PF07700.15 KFP07450.1 - 9.3e-16 58.2 0.3 1.5e-15 57.6 0.3 1.3 1 0 0 1 1 1 1 Haem-NO-binding DUF4761 PF15958.5 KFP07450.1 - 0.13 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4761) ACPS PF01648.20 KFP07451.1 - 1.1e-19 70.7 0.1 4.9e-17 62.1 0.0 2.3 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase superfamily BTB PF00651.31 KFP07452.1 - 3.1e-27 95.0 1.0 3.1e-27 95.0 1.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFP07452.1 - 6e-27 93.8 3.7 1.6e-26 92.4 3.7 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFP07452.1 - 1.4e-25 88.7 3.7 1.7e-05 24.9 0.0 6.7 3 1 3 6 6 6 5 Kelch motif Kelch_1 PF01344.25 KFP07452.1 - 3.1e-25 87.5 8.0 1.3e-06 27.8 0.0 6.3 6 1 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KFP07452.1 - 7.5e-12 45.1 0.1 0.047 13.7 0.0 5.1 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP07452.1 - 8.3e-10 38.7 0.1 1.4 9.3 0.0 5.1 4 1 0 4 4 4 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP07452.1 - 9.1e-07 28.6 4.8 0.11 12.6 0.0 5.8 6 1 0 6 6 6 2 Kelch motif Kelch_5 PF13854.6 KFP07452.1 - 0.0084 16.1 0.5 7.3 6.7 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Myb_DNA-bind_5 PF13873.6 KFP07453.1 - 2.7e-23 81.8 6.4 2.7e-23 81.8 6.4 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 KFP07453.1 - 0.00043 20.4 0.7 0.00043 20.4 0.7 2.6 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KFP07453.1 - 0.01 16.2 2.5 0.027 14.9 2.5 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain ANF_receptor PF01094.28 KFP07454.1 - 1.5e-65 221.6 0.0 2.2e-65 221.1 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 KFP07454.1 - 3.2e-59 199.1 0.0 5.1e-59 198.4 0.0 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFP07454.1 - 1.1e-44 151.3 0.3 2.4e-44 150.2 0.0 1.7 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFP07454.1 - 1.4e-23 83.5 0.0 2.5e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.6 KFP07454.1 - 0.00098 18.9 0.0 0.012 15.3 0.0 2.3 2 1 0 2 2 2 1 Periplasmic binding protein Ion_trans_2 PF07885.16 KFP07454.1 - 5.2 7.1 7.4 5.2 7.1 0.1 3.4 3 0 0 3 3 3 0 Ion channel Actin PF00022.19 KFP07455.1 - 2.7e-140 467.6 0.0 9.2e-140 465.8 0.0 1.7 1 1 0 1 1 1 1 Actin Nucleoporin_C PF03177.14 KFP07457.1 - 8.9e-27 94.1 12.6 2e-26 92.9 9.6 2.6 1 1 1 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KFP07457.1 - 1.4e-07 30.6 0.1 0.014 14.1 0.0 2.2 2 0 0 2 2 2 2 Nup133 N terminal like ABC_membrane PF00664.23 KFP07458.1 - 6.2e-61 206.5 5.5 8.7e-61 206.0 5.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFP07458.1 - 4.1e-33 114.8 0.0 9.5e-33 113.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFP07458.1 - 1.6e-07 31.0 0.0 5.6e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA PF00004.29 KFP07458.1 - 0.00059 20.3 0.5 0.009 16.4 0.2 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFP07458.1 - 0.0014 19.0 0.3 0.0052 17.2 0.3 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KFP07458.1 - 0.0021 17.8 0.0 0.0047 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KFP07458.1 - 0.0024 17.5 0.0 0.006 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFP07458.1 - 0.0037 17.6 0.2 0.024 14.9 0.2 2.2 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 KFP07458.1 - 0.0067 15.3 0.1 0.1 11.4 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_5 PF07728.14 KFP07458.1 - 0.013 15.5 0.2 0.093 12.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 KFP07458.1 - 0.014 15.2 0.2 0.2 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFP07458.1 - 0.021 14.7 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 KFP07458.1 - 0.025 14.3 0.1 0.093 12.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFP07458.1 - 0.056 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KFP07458.1 - 0.085 13.0 0.0 0.37 10.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KFP07458.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KFP07458.1 - 0.17 12.4 0.0 0.47 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFP07458.1 - 0.18 11.5 0.1 0.58 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KFP07458.1 - 0.19 11.0 0.0 0.53 9.5 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin WD40 PF00400.32 KFP07459.1 - 8.6e-52 172.0 6.7 5.5e-10 39.7 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KFP07459.1 - 9.9e-31 106.7 3.8 1.6e-30 106.0 3.8 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KFP07459.1 - 1.4e-12 47.8 0.0 0.0033 17.7 0.0 4.5 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP07459.1 - 3.5e-05 22.7 0.4 0.51 8.9 0.1 3.6 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFP07459.1 - 0.00059 18.9 0.0 0.16 10.9 0.0 3.5 1 1 3 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFP07459.1 - 0.0045 16.9 0.0 0.047 13.6 0.0 2.5 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KFP07459.1 - 0.017 14.5 0.0 6.4 6.0 0.0 2.9 1 1 2 3 3 3 0 WD40-like domain Nbas_N PF15492.6 KFP07459.1 - 0.066 12.5 0.0 0.35 10.2 0.0 2.1 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Glycos_transf_2 PF00535.26 KFP07460.1 - 6.5e-29 100.9 0.0 1.1e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFP07460.1 - 2.7e-23 82.6 2.7 4.6e-23 81.9 2.7 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 KFP07460.1 - 3.1e-06 27.2 0.0 4.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KFP07460.1 - 0.00012 21.7 0.0 0.00026 20.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KFP07460.1 - 0.0003 20.4 0.0 0.00067 19.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.6 KFP07460.1 - 0.0052 17.5 1.1 0.39 11.5 0.2 3.1 2 1 2 4 4 4 2 Ricin-type beta-trefoil lectin domain-like DDE_Tnp_1_7 PF13843.6 KFP07461.1 - 3.4e-84 283.1 0.5 3.9e-84 282.9 0.5 1.0 1 0 0 1 1 1 1 Transposase IS4 HEPN PF05168.14 KFP07461.1 - 0.066 13.3 0.0 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 HEPN domain DUF3510 PF12022.8 KFP07462.1 - 7.7e-42 142.7 2.3 8.3e-42 142.5 0.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) COG2 PF06148.11 KFP07462.1 - 3.5e-09 36.9 0.8 3.5e-09 36.9 0.8 3.7 5 0 0 5 5 5 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 KFP07462.1 - 0.013 15.6 4.4 0.053 13.6 0.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Condensin2nSMC PF12422.8 KFP07462.1 - 0.061 13.5 0.1 2.7 8.2 0.0 2.7 2 1 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit Baculo_PEP_C PF04513.12 KFP07462.1 - 0.32 11.0 1.1 8.6 6.4 0.0 3.2 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Serpin PF00079.20 KFP07463.1 - 9.2e-59 199.6 0.0 1.2e-58 199.3 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Peptidase_C2 PF00648.21 KFP07464.1 - 6.8e-131 435.7 0.0 1.1e-130 435.1 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KFP07464.1 - 2.3e-49 167.3 0.0 3.8e-49 166.6 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_1 PF00036.32 KFP07464.1 - 9.9e-12 43.5 2.5 4.5e-05 22.7 0.1 4.3 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 KFP07464.1 - 3.8e-11 42.0 1.5 0.00057 19.6 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KFP07464.1 - 3.3e-10 39.6 1.0 2.9e-08 33.4 0.1 3.3 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.6 KFP07464.1 - 9.9e-05 22.7 1.5 0.065 13.7 0.1 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP07464.1 - 0.009 15.5 1.7 1.3 8.6 0.0 3.5 3 0 0 3 3 3 1 EF hand EF-hand_4 PF12763.7 KFP07464.1 - 0.0093 15.9 1.0 0.027 14.4 1.0 1.8 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand DUF4706 PF15797.5 KFP07466.1 - 1.2e-23 83.6 0.1 1.3e-23 83.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4706) TPR_1 PF00515.28 KFP07467.1 - 8e-29 98.3 13.8 2.1e-08 33.6 0.3 7.9 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 KFP07467.1 - 1.3e-27 93.7 7.0 3.3e-06 26.8 0.3 7.7 6 2 1 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 KFP07467.1 - 7.5e-21 72.6 3.5 5.6e-05 23.0 0.2 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 KFP07467.1 - 3.3e-20 71.5 0.3 2.6e-06 27.0 0.1 7.3 4 1 3 7 7 7 4 TPR repeat TPR_9 PF13371.6 KFP07467.1 - 2.2e-15 56.6 3.0 2.9e-05 24.1 0.2 4.8 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFP07467.1 - 3.3e-14 53.2 0.3 0.00026 21.5 0.0 3.7 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFP07467.1 - 1.2e-13 51.3 4.9 3.5e-06 27.4 0.5 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFP07467.1 - 1.8e-13 50.6 10.0 5.1e-06 26.7 0.9 4.5 3 2 1 4 4 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFP07467.1 - 2.9e-13 49.2 0.2 1.2 9.7 0.0 6.6 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFP07467.1 - 1.3e-11 44.3 7.3 0.019 15.8 0.1 6.6 2 1 5 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP07467.1 - 2e-05 24.7 4.7 0.0027 17.9 1.1 3.8 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KFP07467.1 - 5.8e-05 22.8 5.2 0.0047 16.9 0.2 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFP07467.1 - 7.1e-05 22.5 5.4 0.13 12.2 0.1 5.2 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP07467.1 - 0.00024 20.6 2.3 0.012 15.0 0.7 3.0 1 1 3 4 4 4 2 MalT-like TPR region NARP1 PF12569.8 KFP07467.1 - 0.00049 19.1 0.8 0.16 10.8 0.3 2.4 2 1 0 2 2 2 2 NMDA receptor-regulated protein 1 SHNi-TPR PF10516.9 KFP07467.1 - 0.00082 18.8 9.1 2.2 7.8 0.1 4.7 5 0 0 5 5 5 1 SHNi-TPR TPR_6 PF13174.6 KFP07467.1 - 0.0011 19.5 5.7 6.2 7.7 0.1 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat BTAD PF03704.17 KFP07467.1 - 0.0043 17.5 0.9 1.3 9.5 0.1 2.7 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_21 PF09976.9 KFP07467.1 - 0.0054 16.5 0.2 1.8 8.2 0.0 2.6 1 1 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_15 PF13429.6 KFP07467.1 - 0.048 12.9 0.6 4.7 6.3 0.0 2.5 1 1 0 2 2 2 0 Tetratricopeptide repeat Rapsyn_N PF10579.9 KFP07467.1 - 0.12 12.5 0.8 5.3 7.2 0.0 2.6 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region Arv1 PF04161.13 KFP07468.1 - 2.1e-48 165.3 4.5 2.4e-48 165.1 4.5 1.1 1 0 0 1 1 1 1 Arv1-like family SPRY PF00622.28 KFP07469.1 - 2.3e-11 43.8 0.0 3.7e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 SPRY domain zf-B_box PF00643.24 KFP07469.1 - 2.2e-09 37.3 3.8 5.7e-09 36.0 3.8 1.8 1 0 0 1 1 1 1 B-box zinc finger fn3 PF00041.21 KFP07469.1 - 8.4e-09 35.7 0.0 1.8e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain PRY PF13765.6 KFP07469.1 - 1.5e-05 24.6 0.1 3.5e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 SPRY-associated domain Laminin_G_3 PF13385.6 KFP07469.1 - 0.012 15.7 0.5 0.036 14.2 0.1 1.9 2 0 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily zf-UBR PF02207.20 KFP07469.1 - 0.04 14.1 3.1 0.13 12.5 3.1 1.9 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DUF1281 PF06924.11 KFP07469.1 - 0.12 11.9 0.4 0.2 11.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) DUF4602 PF15375.6 KFP07470.1 - 5.5e-18 65.6 15.1 6.1e-18 65.4 15.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4602) DDE_Tnp_1_2 PF13586.6 KFP07470.1 - 0.99 9.8 3.9 0.37 11.2 1.6 1.5 1 1 1 2 2 2 0 Transposase DDE domain PDCD2_C PF04194.13 KFP07471.1 - 2.6e-48 164.4 0.7 2.9e-48 164.2 0.7 1.0 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain TBP PF00352.21 KFP07472.1 - 1.1e-63 211.2 0.2 3.5e-32 110.2 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KFP07472.1 - 0.00067 19.7 1.7 1.6 8.9 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF3378) ANAPC_CDC26 PF10471.9 KFP07472.1 - 0.0019 19.0 11.1 0.0037 18.1 11.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 DUF2722 PF10846.8 KFP07472.1 - 0.022 13.7 8.0 0.031 13.3 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 KFP07472.1 - 0.042 13.9 9.1 0.048 13.7 9.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NUDE_C PF04880.13 KFP07472.1 - 0.12 12.9 5.5 0.17 12.4 5.5 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Spt20 PF12090.8 KFP07472.1 - 0.39 10.3 15.1 0.57 9.8 15.1 1.2 1 0 0 1 1 1 0 Spt20 family MAP65_ASE1 PF03999.12 KFP07472.1 - 0.4 9.3 5.2 0.47 9.1 5.2 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Proteasome PF00227.26 KFP07473.1 - 1e-26 93.6 0.1 1.3e-26 93.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Cytochrom_C1 PF02167.15 KFP07473.1 - 0.0011 18.8 0.1 0.0013 18.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome C1 family zf-H2C2_2 PF13465.6 KFP07474.1 - 1.5e-48 161.2 53.0 4.2e-10 39.6 1.3 7.0 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFP07474.1 - 2.8e-41 137.7 52.8 8e-08 32.3 4.6 7.1 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP07474.1 - 5.3e-27 92.2 49.4 5.3e-05 23.7 0.4 7.1 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP07474.1 - 8.6e-18 64.1 16.5 0.0093 16.2 1.0 6.3 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP07474.1 - 5.2e-16 58.2 36.2 0.00047 20.1 0.6 6.4 6 0 0 6 6 6 5 C2H2-type zinc finger zf_UBZ PF18439.1 KFP07474.1 - 3.3e-13 49.0 13.4 0.21 11.2 0.0 6.4 6 0 0 6 6 6 4 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFP07474.1 - 1.4e-12 47.5 17.1 0.00043 20.4 1.9 4.0 3 1 0 3 3 3 3 Zinc ribbon domain zf-C2HC_2 PF13913.6 KFP07474.1 - 3.7e-12 45.8 26.6 0.009 15.9 0.3 6.4 6 0 0 6 6 6 4 zinc-finger of a C2HC-type zinc_ribbon_9 PF14369.6 KFP07474.1 - 4.5e-11 42.8 15.0 0.11 12.8 0.1 6.1 6 0 0 6 6 6 2 zinc-ribbon DZR PF12773.7 KFP07474.1 - 1.2e-10 41.2 11.7 0.0087 16.1 0.5 3.3 3 0 0 3 3 3 3 Double zinc ribbon zf-Di19 PF05605.12 KFP07474.1 - 2.4e-10 40.5 40.0 2e-05 24.8 0.5 4.9 1 1 5 6 6 5 5 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 KFP07474.1 - 7.5e-10 38.5 2.1 0.024 14.5 0.0 4.2 2 1 2 4 4 4 2 GAGA factor zf-met PF12874.7 KFP07474.1 - 9.7e-10 38.5 28.8 0.19 12.1 0.4 6.3 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFP07474.1 - 4.8e-09 35.8 29.3 0.00053 19.7 0.4 7.0 7 0 0 7 7 7 3 zinc-finger C2H2-type TerY_C PF15616.6 KFP07474.1 - 1.3e-08 35.0 7.2 0.011 15.9 0.1 3.1 2 1 1 3 3 3 3 TerY-C metal binding domain XPA_N PF01286.18 KFP07474.1 - 2.2e-08 34.0 12.5 0.84 9.7 0.2 6.3 6 0 0 6 6 6 1 XPA protein N-terminal HypA PF01155.19 KFP07474.1 - 5.7e-08 32.8 8.6 0.061 13.4 0.2 3.3 1 1 2 3 3 3 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.5 KFP07474.1 - 1.4e-07 32.1 11.4 0.06 14.1 0.3 3.3 1 1 2 3 3 3 3 zinc-ribbon family zf-RING_7 PF02591.15 KFP07474.1 - 1.7e-07 31.3 18.3 2 8.7 0.2 6.1 6 0 0 6 6 6 2 C4-type zinc ribbon domain YhfH PF14149.6 KFP07474.1 - 2.8e-07 30.4 15.4 5.2 7.1 0.0 6.2 6 0 0 6 6 6 0 YhfH-like protein zf-LYAR PF08790.11 KFP07474.1 - 4.4e-07 29.7 27.6 0.48 10.4 0.3 6.7 7 0 0 7 7 6 3 LYAR-type C2HC zinc finger DUF3268 PF11672.8 KFP07474.1 - 1.2e-06 28.9 11.1 0.21 11.9 0.4 3.2 3 0 0 3 3 3 3 zinc-finger-containing domain CpXC PF14353.6 KFP07474.1 - 3.4e-06 27.1 19.1 0.24 11.5 0.1 5.8 1 1 3 4 4 4 2 CpXC protein zf-trcl PF13451.6 KFP07474.1 - 1.3e-05 25.0 11.0 8.5 6.4 0.0 6.0 6 0 0 6 6 6 0 Probable zinc-ribbon domain FYDLN_acid PF09538.10 KFP07474.1 - 2.6e-05 24.8 13.2 3.9 8.2 0.1 5.1 1 1 3 4 4 4 0 Protein of unknown function (FYDLN_acid) zf-AN1 PF01428.16 KFP07474.1 - 2.8e-05 24.2 21.7 3.3 7.9 0.1 6.3 6 0 0 6 6 6 0 AN1-like Zinc finger zf-C2H2_9 PF16293.5 KFP07474.1 - 3.6e-05 23.5 7.9 2.9 7.8 0.0 5.0 5 1 0 5 5 4 0 C2H2 type zinc-finger (1 copy) DUF2256 PF10013.9 KFP07474.1 - 0.00013 22.0 13.3 27 5.0 0.0 6.1 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-BED PF02892.15 KFP07474.1 - 0.00019 21.3 30.2 1 9.5 0.3 6.1 2 2 3 5 5 5 1 BED zinc finger zf-ribbon_3 PF13248.6 KFP07474.1 - 0.00021 20.6 29.5 0.44 10.0 0.1 6.2 6 0 0 6 6 6 3 zinc-ribbon domain zinc_ribbon_5 PF13719.6 KFP07474.1 - 0.00027 20.6 19.0 0.63 9.8 0.2 5.8 5 1 0 5 5 5 1 zinc-ribbon domain zf-HIT PF04438.16 KFP07474.1 - 0.00037 20.3 25.9 0.73 9.8 0.3 5.8 6 0 0 6 6 6 3 HIT zinc finger Evr1_Alr PF04777.13 KFP07474.1 - 0.00043 20.7 15.5 0.23 12.0 0.8 5.5 1 1 3 4 4 4 1 Erv1 / Alr family ARS2 PF04959.13 KFP07474.1 - 0.00081 19.8 14.3 0.51 10.7 0.1 4.0 1 1 3 4 4 4 2 Arsenite-resistance protein 2 Zn_ribbon_SprT PF17283.2 KFP07474.1 - 0.002 18.0 37.8 0.6 10.1 5.0 6.4 1 1 5 6 6 6 3 SprT-like zinc ribbon domain zinc-ribbons_6 PF07191.12 KFP07474.1 - 0.0022 17.9 15.9 3.5e+03 -1.9 15.9 4.6 1 1 0 1 1 0 0 zinc-ribbons zinc_ribbon_4 PF13717.6 KFP07474.1 - 0.0024 17.7 24.1 6.4 6.8 3.6 6.0 5 1 1 6 6 6 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 KFP07474.1 - 0.0026 17.7 30.8 0.45 10.5 4.8 5.0 3 2 2 5 5 5 2 Transposase zinc-ribbon domain TFIIS_C PF01096.18 KFP07474.1 - 0.0029 17.4 22.5 5.4 7.0 0.1 6.1 6 0 0 6 6 6 0 Transcription factor S-II (TFIIS) zf-C2H2_8 PF15909.5 KFP07474.1 - 0.0031 17.8 20.0 0.88 9.9 4.7 3.8 1 1 2 3 3 3 2 C2H2-type zinc ribbon IBR PF01485.21 KFP07474.1 - 0.0035 17.5 21.8 0.23 11.7 1.4 4.3 1 1 3 4 4 4 2 IBR domain, a half RING-finger domain Terminase_GpA PF05876.12 KFP07474.1 - 0.0046 15.6 18.4 0.31 9.5 0.4 3.0 1 1 2 3 3 3 3 Phage terminase large subunit (GpA) Zn-C2H2_12 PF18112.1 KFP07474.1 - 0.0092 16.4 12.0 14 6.3 0.2 5.2 6 0 0 6 6 4 0 Autophagy receptor zinc finger-C2H2 domain YacG PF03884.14 KFP07474.1 - 0.0094 15.7 14.8 3.7 7.3 0.1 5.5 6 0 0 6 6 6 0 DNA gyrase inhibitor YacG HalOD2 PF18547.1 KFP07474.1 - 0.0099 15.8 20.8 0.45 10.4 1.5 5.1 4 2 0 4 4 4 1 Halobacterial output domain 2 zf-C2HE PF16278.5 KFP07474.1 - 0.02 15.4 29.0 0.77 10.3 0.3 6.1 3 1 3 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger ADK_lid PF05191.14 KFP07474.1 - 0.021 14.8 22.8 0.21 11.6 0.4 5.6 4 1 2 6 6 6 0 Adenylate kinase, active site lid zf-MYST PF17772.1 KFP07474.1 - 0.027 14.1 10.9 14 5.4 0.1 5.3 2 2 4 6 6 6 0 MYST family zinc finger domain zf-C4_Topoisom PF01396.19 KFP07474.1 - 0.028 14.2 13.8 9.9 6.0 0.2 4.8 4 0 0 4 4 4 0 Topoisomerase DNA binding C4 zinc finger C1_4 PF07975.12 KFP07474.1 - 0.037 14.3 17.5 2.3 8.5 0.8 4.5 1 1 2 4 4 4 0 TFIIH C1-like domain zf-C2H2_2 PF12756.7 KFP07474.1 - 0.056 13.8 19.0 4.1 7.8 0.1 5.7 1 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) Cys_rich_CPXG PF14255.6 KFP07474.1 - 0.062 13.2 16.1 34 4.4 0.1 6.0 6 0 0 6 6 6 0 Cysteine-rich CPXCG LIM PF00412.22 KFP07474.1 - 0.07 13.4 16.6 12 6.3 0.6 5.0 1 1 3 5 5 5 0 LIM domain DNA_RNApol_7kD PF03604.13 KFP07474.1 - 0.081 12.6 18.6 13 5.6 0.1 6.1 6 0 0 6 6 6 0 DNA directed RNA polymerase, 7 kDa subunit zf-H2C2_5 PF13909.6 KFP07474.1 - 0.19 11.5 0.5 0.19 11.5 0.5 9.8 11 2 0 11 11 8 0 C2H2-type zinc-finger domain DUF2225 PF09986.9 KFP07474.1 - 0.22 11.2 13.2 4.2 7.0 0.1 4.5 3 2 1 4 4 3 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-Mss51 PF13824.6 KFP07474.1 - 0.22 11.7 36.3 1.7 8.8 0.5 6.0 2 2 3 5 5 5 0 Zinc-finger of mitochondrial splicing suppressor 51 PHD PF00628.29 KFP07474.1 - 0.26 11.2 17.9 3.3 7.7 1.9 4.2 4 0 0 4 4 4 0 PHD-finger Zf_RING PF16744.5 KFP07474.1 - 0.28 11.3 13.9 6.7 6.9 0.1 5.2 1 1 3 6 6 5 0 KIAA1045 RING finger Rad50_zn_hook PF04423.14 KFP07474.1 - 0.39 10.6 12.5 19 5.2 0.1 4.3 3 1 1 4 4 4 0 Rad50 zinc hook motif Sgf11 PF08209.11 KFP07474.1 - 0.4 10.3 15.3 16 5.1 0.0 5.5 6 0 0 6 6 6 0 Sgf11 (transcriptional regulation protein) OrfB_Zn_ribbon PF07282.11 KFP07474.1 - 0.42 10.6 22.8 3.9 7.5 2.3 5.0 1 1 3 5 5 5 0 Putative transposase DNA-binding domain ComK PF06338.11 KFP07474.1 - 0.53 9.9 3.2 9.9 5.8 0.3 2.2 1 1 1 2 2 2 0 ComK protein Ogr_Delta PF04606.12 KFP07474.1 - 0.54 10.3 26.5 0.13 12.3 2.4 5.5 4 2 1 5 5 5 0 Ogr/Delta-like zinc finger Zn_ribbon_recom PF13408.6 KFP07474.1 - 0.68 10.5 26.4 19 5.9 0.2 5.5 1 1 3 4 4 3 0 Recombinase zinc beta ribbon domain TRAF6_Z2 PF18048.1 KFP07474.1 - 0.69 10.0 16.6 3.4 7.8 0.2 5.2 6 0 0 6 6 4 0 TNF receptor-associated factor 6 zinc finger 2 ATPase-cat_bd PF12156.8 KFP07474.1 - 1.2 10.0 18.7 2.4 9.0 1.9 3.3 3 0 0 3 3 3 0 Putative metal-binding domain of cation transport ATPase PADR1 PF08063.12 KFP07474.1 - 1.4 8.7 19.4 9.1 6.2 0.1 5.7 6 0 0 6 6 6 0 PADR1 (NUC008) domain Mut7-C PF01927.16 KFP07474.1 - 1.9 8.6 19.3 36 4.4 1.2 5.2 1 1 4 5 5 5 0 Mut7-C RNAse domain Nudix_N_2 PF14803.6 KFP07474.1 - 2 8.4 22.8 36 4.4 0.2 6.1 5 1 1 6 6 6 0 Nudix N-terminal Ribosomal_L37ae PF01780.19 KFP07474.1 - 2.4 8.3 22.4 79 3.4 0.1 5.8 2 1 2 4 4 4 0 Ribosomal L37ae protein family zf-3CxxC_2 PF17180.4 KFP07474.1 - 3.4 8.5 28.0 20 6.0 0.3 6.0 2 2 3 6 6 6 0 Zinc-binding domain zf-RING_5 PF14634.6 KFP07474.1 - 6.3 6.8 24.6 18 5.4 3.1 4.9 3 3 1 4 4 4 0 zinc-RING finger domain VWD PF00094.25 KFP07475.1 - 0.00024 21.4 0.1 0.00031 21.1 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type D domain VWD PF00094.25 KFP07476.1 - 3.3e-07 30.7 0.0 3.3e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type D domain zf-H2C2_2 PF13465.6 KFP07477.1 - 1.1e-22 79.4 10.3 1.7e-08 34.5 0.3 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFP07477.1 - 1.5e-13 50.3 23.3 3.6e-06 27.1 1.9 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP07477.1 - 1.5e-07 31.6 20.2 0.00087 19.9 0.7 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFP07477.1 - 0.00065 19.8 5.5 0.0009 19.3 1.1 2.2 1 1 1 2 2 2 1 Zinc ribbon domain zf-C2H2_jaz PF12171.8 KFP07477.1 - 0.0014 18.9 7.5 0.073 13.4 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf_ZIC PF18366.1 KFP07477.1 - 0.0014 18.7 1.3 1.6 8.9 0.1 2.4 1 1 1 2 2 2 2 Zic proteins zinc finger domain zf-C2H2_6 PF13912.6 KFP07477.1 - 0.0022 17.9 16.5 0.015 15.3 0.8 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFP07477.1 - 0.0037 17.5 2.3 0.006 16.8 2.3 1.5 1 1 0 1 1 1 1 C2H2-type zinc ribbon DZR PF12773.7 KFP07477.1 - 0.0052 16.8 7.4 0.17 12.0 7.4 2.1 1 1 0 1 1 1 1 Double zinc ribbon Prok-RING_1 PF14446.6 KFP07477.1 - 0.0053 16.7 1.0 5.4 7.0 0.0 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf_UBZ PF18439.1 KFP07477.1 - 0.013 15.0 5.6 0.67 9.6 0.1 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 KFP07477.1 - 0.016 15.6 6.6 0.047 14.1 0.7 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type LIM PF00412.22 KFP07477.1 - 0.025 14.8 7.0 3.2 8.0 3.1 2.6 2 1 0 2 2 2 0 LIM domain zf-C2H2_3rep PF18868.1 KFP07477.1 - 0.028 15.1 1.8 3.7 8.2 0.2 2.1 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-LYAR PF08790.11 KFP07477.1 - 0.028 14.3 11.1 0.12 12.3 0.4 2.9 3 1 0 3 3 3 0 LYAR-type C2HC zinc finger HypA PF01155.19 KFP07477.1 - 0.03 14.3 3.4 0.061 13.3 1.2 1.8 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.5 KFP07477.1 - 0.047 14.4 2.9 0.19 12.5 2.9 1.8 1 1 0 1 1 1 0 zinc-ribbon family zf-Di19 PF05605.12 KFP07477.1 - 0.058 13.7 10.8 0.085 13.2 2.9 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 KFP07477.1 - 0.063 13.2 1.2 0.063 13.2 1.2 3.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type DUF2256 PF10013.9 KFP07477.1 - 0.096 12.8 8.4 6.9 6.9 0.2 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-AN1 PF01428.16 KFP07477.1 - 0.13 12.4 10.6 2.2 8.5 0.4 3.2 2 1 1 3 3 3 0 AN1-like Zinc finger C1_4 PF07975.12 KFP07477.1 - 0.16 12.3 6.3 1.5 9.1 6.3 2.1 1 1 0 1 1 1 0 TFIIH C1-like domain zf-C2H2_2 PF12756.7 KFP07477.1 - 0.16 12.3 4.4 3.7 7.9 0.1 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) C1_1 PF00130.22 KFP07477.1 - 0.17 11.8 6.2 0.81 9.6 1.3 2.6 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 KFP07477.1 - 0.51 10.3 5.2 4.2 7.3 5.4 2.1 1 1 0 1 1 1 0 PHD-finger CpXC PF14353.6 KFP07477.1 - 0.53 10.3 0.1 0.53 10.3 0.1 2.9 1 1 2 3 3 3 0 CpXC protein FYDLN_acid PF09538.10 KFP07477.1 - 0.65 10.7 4.6 9.3 7.0 0.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-C2HE PF16278.5 KFP07477.1 - 0.76 10.3 9.9 1.7 9.2 0.6 2.8 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Elf1 PF05129.13 KFP07477.1 - 2 8.5 6.9 0.53 10.4 1.8 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.7 KFP07477.1 - 3.8 7.6 10.2 2.2 8.3 4.3 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain GAGA PF09237.11 KFP07477.1 - 3.8 7.4 9.1 0.7 9.7 0.2 2.6 1 1 2 3 3 3 0 GAGA factor ADK_lid PF05191.14 KFP07477.1 - 4.2 7.4 8.7 0.17 11.9 0.8 2.7 3 1 1 4 4 3 0 Adenylate kinase, active site lid XPA_N PF01286.18 KFP07477.1 - 5.4 7.2 7.3 16 5.6 0.0 2.8 3 0 0 3 3 3 0 XPA protein N-terminal DUF2197 PF09963.9 KFP07477.1 - 9.1 6.6 9.0 4 7.8 1.8 3.2 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) TRAPPC9-Trs120 PF08626.11 KFP07478.1 - 1.3e-46 158.7 0.7 1.4e-20 72.4 0.1 6.2 3 2 1 4 4 4 4 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Vps23_core PF09454.10 KFP07478.1 - 0.04 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Vps23 core domain RNA_pol_3_Rpc31 PF11705.8 KFP07479.1 - 0.11 12.8 7.5 0.11 12.7 7.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 rRNA_processing PF08524.11 KFP07479.1 - 0.12 12.3 3.5 0.13 12.3 3.2 1.3 1 1 0 1 1 1 0 rRNA processing TPX2_importin PF12214.8 KFP07479.1 - 0.13 12.5 0.3 0.17 12.1 0.1 1.4 1 1 0 1 1 1 0 Cell cycle regulated microtubule associated protein NOA36 PF06524.12 KFP07479.1 - 0.3 10.4 4.5 0.29 10.4 4.5 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KFP07479.1 - 0.86 7.6 9.3 0.96 7.5 9.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 KFP07479.1 - 6.2 7.3 12.0 8.5 6.8 12.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pkinase_Tyr PF07714.17 KFP07480.1 - 1.8e-93 312.6 0.0 2.8e-93 311.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP07480.1 - 6.8e-46 156.8 0.0 1.6e-45 155.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain FERM_N_2 PF18038.1 KFP07480.1 - 5.4e-44 149.0 0.2 2e-43 147.2 0.2 2.0 1 0 0 1 1 1 1 FERM N-terminal domain Focal_AT PF03623.13 KFP07480.1 - 8e-38 129.4 0.6 2.2e-37 128.0 0.6 1.7 1 0 0 1 1 1 1 Focal adhesion targeting region FERM_M PF00373.18 KFP07480.1 - 1.7e-11 44.5 0.1 1.7e-11 44.5 0.1 2.4 3 0 0 3 3 3 1 FERM central domain Haspin_kinase PF12330.8 KFP07480.1 - 0.0013 17.8 0.0 0.0025 16.8 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFP07480.1 - 0.0084 15.5 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FERM_F2 PF18377.1 KFP07480.1 - 0.019 14.9 0.3 0.051 13.5 0.3 1.8 1 0 0 1 1 1 0 FERM F2 acyl-CoA binding protein-like domain FERM_N PF09379.10 KFP07480.1 - 0.14 12.2 0.0 1.4 9.0 0.0 2.6 3 0 0 3 3 3 0 FERM N-terminal domain uDENN PF03456.18 KFP07481.1 - 9.4e-06 26.3 0.0 1.9e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 uDENN domain dDENN PF03455.19 KFP07482.1 - 3.4e-07 30.1 0.5 1.1e-06 28.5 0.5 1.9 1 0 0 1 1 1 1 dDENN domain bPH_3 PF14470.6 KFP07482.1 - 0.084 13.2 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 Bacterial PH domain MFS_1 PF07690.16 KFP07483.1 - 3.7e-16 59.0 17.4 6.6e-10 38.4 3.3 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 KFP07483.1 - 3.8e-09 35.6 0.5 3.8e-09 35.6 0.5 2.5 2 1 0 2 2 2 1 MFS/sugar transport protein OATP PF03137.20 KFP07483.1 - 0.0059 15.0 3.6 0.21 9.9 0.1 2.8 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family 7tm_1 PF00001.21 KFP07484.1 - 2.7e-30 105.6 32.4 4.3e-30 104.9 32.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF5412 PF17428.2 KFP07484.1 - 0.66 9.8 0.0 0.66 9.8 0.0 3.5 2 1 1 3 3 3 0 Family of unknown function (DUF5412) Phage_holin_3_6 PF07332.11 KFP07484.1 - 4.9 7.2 7.4 18 5.4 0.9 2.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DSPc PF00782.20 KFP07486.1 - 1.8e-08 34.3 0.0 2.4e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP07486.1 - 4.2e-07 29.8 0.0 6.7e-07 29.1 0.0 1.3 1 1 0 1 1 1 1 Protein-tyrosine phosphatase RVT_1 PF00078.27 KFP07492.1 - 3.1e-21 75.9 0.0 4.3e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 KFP07492.1 - 7.3e-14 51.4 0.3 1.2e-13 50.7 0.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase thumb domain Brix PF04427.18 KFP07493.1 - 3.5e-15 56.6 0.3 4e-15 56.4 0.3 1.1 1 0 0 1 1 1 1 Brix domain adh_short PF00106.25 KFP07494.1 - 3.7e-40 137.5 0.2 4.1e-40 137.3 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP07494.1 - 6.7e-29 101.1 0.0 7.9e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP07494.1 - 9.4e-06 25.7 0.1 1.2e-05 25.3 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFP07494.1 - 0.00022 20.7 0.0 0.00027 20.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KFP07494.1 - 0.012 15.1 0.0 0.066 12.7 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Baculo_E66 PF04850.12 KFP07494.1 - 0.076 11.8 0.2 0.086 11.6 0.2 1.1 1 0 0 1 1 1 0 Baculovirus E66 occlusion-derived virus envelope protein ADP_PFK_GK PF04587.15 KFP07495.1 - 2.7e-139 464.4 0.0 3e-139 464.3 0.0 1.0 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region Neogenin_C PF06583.12 KFP07496.1 - 3.3e-122 407.9 24.9 6.6e-122 406.9 24.9 1.5 1 0 0 1 1 1 1 Neogenin C-terminus fn3 PF00041.21 KFP07496.1 - 1e-83 275.8 28.0 1.8e-18 66.7 0.1 6.5 6 0 0 6 6 6 6 Fibronectin type III domain I-set PF07679.16 KFP07496.1 - 1.1e-53 179.3 0.2 4e-16 58.8 0.0 6.7 7 0 0 7 7 7 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP07496.1 - 2.1e-48 162.8 0.3 8.4e-13 48.7 0.0 7.2 6 0 0 6 6 6 4 Immunoglobulin domain Ig_2 PF13895.6 KFP07496.1 - 1.6e-34 118.1 0.0 2.2e-07 31.1 0.0 4.8 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 KFP07496.1 - 4.6e-29 100.4 0.0 5.7e-06 26.4 0.0 6.4 6 0 0 6 6 6 4 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFP07496.1 - 7.6e-22 77.7 22.7 0.0004 20.9 2.9 7.7 6 2 0 6 6 6 5 Purple acid Phosphatase, N-terminal domain V-set PF07686.17 KFP07496.1 - 1.9e-14 53.7 7.5 0.00076 19.6 0.0 9.0 5 4 2 7 7 7 1 Immunoglobulin V-set domain Interfer-bind PF09294.10 KFP07496.1 - 2.8e-13 50.1 0.1 0.075 13.4 0.0 5.9 6 0 0 6 6 6 3 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 KFP07496.1 - 2.5e-08 34.2 1.8 4.5 7.7 0.0 6.1 6 0 0 6 6 6 1 Uncharacterised conserved protein (DUF2369) Ig_5 PF16681.5 KFP07496.1 - 3.7e-08 33.7 0.0 0.21 12.0 0.1 4.8 4 1 0 4 4 4 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KFP07496.1 - 2.6e-07 30.6 0.0 0.77 9.9 0.0 4.1 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain fn3_2 PF16893.5 KFP07496.1 - 4.2e-07 30.0 0.0 0.1 12.7 0.0 4.4 4 0 0 4 4 4 1 Fibronectin type III domain fn3_4 PF16794.5 KFP07496.1 - 6.5e-07 29.2 0.7 2.8 7.9 0.0 5.7 5 1 0 5 5 5 1 Fibronectin-III type domain Tissue_fac PF01108.17 KFP07496.1 - 1.2e-06 28.3 5.4 0.0097 15.7 0.0 5.4 5 1 1 6 6 6 2 Tissue factor SusE PF14292.6 KFP07496.1 - 2.5e-05 24.5 0.5 0.032 14.4 0.0 4.2 4 0 0 4 4 4 1 SusE outer membrane protein Ig_4 PF16680.5 KFP07496.1 - 6.7e-05 23.1 0.1 2.8 8.3 0.0 4.4 4 1 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain EphA2_TM PF14575.6 KFP07496.1 - 0.002 19.0 0.3 0.0047 17.8 0.3 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Izumo-Ig PF16706.5 KFP07496.1 - 0.0021 18.1 0.0 0.23 11.5 0.0 3.7 4 1 0 4 4 3 1 Izumo-like Immunoglobulin domain TMEM154 PF15102.6 KFP07496.1 - 0.0028 17.6 3.9 0.0036 17.2 0.0 2.5 2 0 0 2 2 2 1 TMEM154 protein family DUF4959 PF16323.5 KFP07496.1 - 0.0099 16.2 5.8 1.4 9.3 0.0 3.7 4 1 0 4 4 3 2 Domain of unknown function (DUF4959) Ly49 PF08391.10 KFP07496.1 - 0.038 14.3 0.0 0.076 13.4 0.0 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Herpes_UL74 PF07982.12 KFP07496.1 - 0.042 12.8 2.1 0.074 12.0 2.1 1.3 1 0 0 1 1 1 0 Herpes UL74 glycoproteins Ig_6 PF18452.1 KFP07496.1 - 0.05 13.2 0.0 2.3 7.8 0.0 3.2 4 0 0 4 4 3 0 Immunoglobulin domain Shisa PF13908.6 KFP07496.1 - 0.11 12.7 2.3 0.32 11.2 0.0 2.6 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator F5_F8_type_C PF00754.25 KFP07496.1 - 0.13 12.4 3.6 2 8.6 0.1 3.6 4 0 0 4 4 4 0 F5/8 type C domain V-set_CD47 PF08204.11 KFP07496.1 - 0.5 10.4 2.0 3.3 7.7 0.0 3.3 4 1 0 4 4 3 0 CD47 immunoglobulin-like domain Insulin_TMD PF17870.1 KFP07496.1 - 1.1 9.4 4.3 2.8 8.1 4.3 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment NHR2 PF08788.11 KFP07497.1 - 4.9e-40 135.1 8.8 1.5e-39 133.6 8.8 1.9 1 0 0 1 1 1 1 NHR2 domain like TAFH PF07531.14 KFP07497.1 - 2.3e-34 117.4 1.4 4.4e-34 116.5 1.4 1.5 1 0 0 1 1 1 1 NHR1 homology to TAF zf-MYND PF01753.18 KFP07497.1 - 2.9e-07 30.5 18.2 2.9e-07 30.5 18.2 2.0 2 0 0 2 2 2 1 MYND finger Efg1 PF10153.9 KFP07497.1 - 0.027 14.8 2.0 0.081 13.3 2.0 1.7 1 0 0 1 1 1 0 rRNA-processing protein Efg1 DUF3731 PF12531.8 KFP07497.1 - 0.1 12.4 3.7 0.038 13.8 1.0 1.6 2 0 0 2 2 2 0 DNA-K related protein DUF4434 PF14488.6 KFP07497.1 - 0.14 12.2 0.2 0.14 12.2 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4434) MAJIN PF15077.6 KFP07497.1 - 0.31 10.8 3.5 0.64 9.8 3.5 1.5 1 0 0 1 1 1 0 Membrane-anchored junction protein vATP-synt_E PF01991.18 KFP07497.1 - 1.1 8.6 12.4 1.8 7.9 12.4 1.3 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit ARGLU PF15346.6 KFP07497.1 - 2.2 8.1 14.0 0.2 11.5 7.0 2.2 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 DivIVA PF05103.13 KFP07497.1 - 3.3 7.8 9.1 7.9 6.6 9.1 1.6 1 0 0 1 1 1 0 DivIVA protein Yae1_N PF09811.9 KFP07498.1 - 5.6e-14 51.6 46.0 1.8e+04 -10.7 46.0 4.5 1 1 0 1 1 1 0 Essential protein Yae1, N terminal DDE_1 PF03184.19 KFP07499.1 - 1.7e-12 47.3 0.0 3e-12 46.5 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease Lambda_Kil PF06301.11 KFP07499.1 - 0.094 12.3 0.6 12 5.6 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage lambda Kil protein TRIQK PF15168.6 KFP07500.1 - 6.9e-26 90.0 0.8 7.6e-26 89.8 0.8 1.0 1 0 0 1 1 1 1 Triple QxxK/R motif-containing protein family TNFR_16_TM PF18422.1 KFP07500.1 - 3.8 7.5 4.8 5.8 7.0 4.8 1.2 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain FAM92 PF06730.11 KFP07501.1 - 4.7e-102 340.1 10.4 5.4e-102 339.9 10.4 1.0 1 0 0 1 1 1 1 FAM92 protein Vps5 PF09325.10 KFP07501.1 - 0.0045 16.6 7.4 0.25 10.9 4.5 3.0 2 1 1 3 3 3 2 Vps5 C terminal like P4Ha_N PF08336.11 KFP07501.1 - 0.0058 16.6 1.1 0.0058 16.6 1.1 2.1 1 1 1 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 7TMR-HDED PF07697.11 KFP07501.1 - 0.026 14.7 5.0 0.043 13.9 5.0 1.4 1 0 0 1 1 1 0 7TM-HD extracellular CemA PF03040.14 KFP07501.1 - 0.13 12.1 1.3 0.21 11.5 1.3 1.3 1 0 0 1 1 1 0 CemA family RRM_1 PF00076.22 KFP07502.1 - 2.1e-24 85.1 0.1 1.7e-06 27.8 0.2 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Meckelin PF09773.9 KFP07503.1 - 0 1149.7 14.3 0 1149.7 14.3 1.7 2 0 0 2 2 2 1 Meckelin (Transmembrane protein 67) NCD3G PF07562.14 KFP07503.1 - 0.014 15.3 3.5 0.014 15.3 3.5 2.7 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR PP2C PF00481.21 KFP07504.1 - 3.5e-36 125.2 0.0 2.9e-35 122.2 0.0 2.0 1 1 1 2 2 2 1 Protein phosphatase 2C Ras PF00071.22 KFP07505.1 - 5.1e-31 107.5 0.1 1.4e-30 106.0 0.0 1.7 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KFP07505.1 - 7.6e-09 35.8 0.0 1.9e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KFP07505.1 - 1.4e-05 25.2 0.0 2.7e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFP07505.1 - 4.4e-05 23.1 0.1 0.00019 21.0 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFP07505.1 - 0.00024 21.0 0.0 0.75 9.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KFP07505.1 - 0.025 14.6 2.2 0.045 13.8 0.2 2.3 3 0 0 3 3 3 0 Dynamin family pXO2-34 PF17362.2 KFP07505.1 - 0.035 14.0 0.6 16 5.4 0.0 3.3 3 0 0 3 3 3 0 Family of unknown function ABC_tran PF00005.27 KFP07505.1 - 0.039 14.5 0.0 0.076 13.5 0.0 1.8 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KFP07505.1 - 0.068 13.5 0.0 39 4.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF2369 PF10179.9 KFP07505.1 - 0.091 13.2 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) Myb_DNA-bind_5 PF13873.6 KFP07506.1 - 1.1e-21 76.6 0.1 1.1e-21 76.6 0.1 3.0 3 1 0 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KFP07506.1 - 0.067 13.6 0.2 0.14 12.5 0.2 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain zf-C3HC4_2 PF13923.6 KFP07507.1 - 9.2e-10 38.2 8.1 9.2e-10 38.2 8.1 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 KFP07507.1 - 1.2e-07 32.3 3.7 1.2e-07 32.3 3.7 3.4 1 1 2 3 3 3 1 TRAF-type zinc finger zf-C3HC4 PF00097.25 KFP07507.1 - 1.2e-07 31.5 7.5 1.2e-07 31.5 7.5 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP07507.1 - 4.8e-07 29.7 8.5 1.5e-06 28.1 8.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFP07507.1 - 1.8e-06 28.0 6.1 1.8e-06 28.0 6.1 2.7 3 1 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFP07507.1 - 1.8e-06 28.1 7.9 1.8e-06 28.1 7.9 3.1 3 1 0 3 3 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFP07507.1 - 7.6e-06 25.7 3.2 7.6e-06 25.7 3.2 3.0 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 KFP07507.1 - 9e-05 22.5 11.7 0.002 18.1 11.7 2.5 1 1 0 1 1 1 1 Seven in absentia protein family zf-RING_6 PF14835.6 KFP07507.1 - 0.0003 20.6 1.8 0.0003 20.6 1.8 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 KFP07507.1 - 0.0012 18.7 7.3 0.0012 18.7 7.3 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFP07507.1 - 0.0076 16.2 5.7 0.0076 16.2 5.7 2.6 2 1 0 2 2 1 1 zinc-RING finger domain zf-TRAF_2 PF15965.5 KFP07507.1 - 0.015 15.7 8.2 0.015 15.7 8.2 3.4 2 1 1 3 3 3 0 TRAF-like zinc-finger zf-rbx1 PF12678.7 KFP07507.1 - 0.018 15.3 10.7 0.018 15.3 10.7 4.5 4 2 0 4 4 4 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KFP07507.1 - 1.3 9.2 14.4 0.11 12.6 8.7 2.3 2 1 0 2 2 2 0 zinc RING finger of MSL2 VIR_N PF15912.5 KFP07508.1 - 2.2e-96 322.5 16.4 2.2e-96 322.5 16.4 2.4 1 1 1 2 2 2 1 Virilizer, N-terminal SDA1 PF05285.12 KFP07508.1 - 0.0025 17.3 27.1 0.0047 16.4 27.1 1.4 1 0 0 1 1 1 1 SDA1 CDC27 PF09507.10 KFP07508.1 - 1.9 7.8 16.0 4.4 6.6 16.0 1.5 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RRM_1 PF00076.22 KFP07509.1 - 2.5e-15 56.0 0.0 0.00054 19.7 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dpy19 PF10034.9 KFP07510.1 - 1.5e-203 677.7 31.9 1.8e-203 677.4 31.9 1.1 1 0 0 1 1 1 1 Q-cell neuroblast polarisation DUF4405 PF14358.6 KFP07510.1 - 0.016 15.8 0.3 3.8 8.1 0.1 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) Complex1_LYR_1 PF13232.6 KFP07510.1 - 0.081 13.5 0.1 0.25 12.0 0.1 1.8 1 0 0 1 1 1 0 Complex1_LYR-like Lig_chan PF00060.26 KFP07510.1 - 7.5 6.4 6.1 7.7 6.3 2.0 2.6 2 0 0 2 2 2 0 Ligand-gated ion channel DUF4229 PF14012.6 KFP07510.1 - 8 6.6 8.9 12 6.1 1.7 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Cadherin PF00028.17 KFP07511.1 - 5.4e-214 693.5 24.8 1.3e-20 73.6 0.0 15.4 15 0 0 15 15 15 15 Cadherin domain Cadherin_C PF01049.17 KFP07511.1 - 1.2e-40 139.2 0.1 2.8e-40 138.0 0.1 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic region Laminin_G_2 PF02210.24 KFP07511.1 - 4.8e-33 114.4 1.0 2.4e-18 66.9 0.0 3.0 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 KFP07511.1 - 2.4e-26 92.5 0.1 5.1e-12 46.1 0.1 2.8 2 0 0 2 2 2 2 Laminin G domain EGF PF00008.27 KFP07511.1 - 3.2e-13 49.7 48.9 2.8e-05 24.3 8.8 4.6 4 0 0 4 4 4 4 EGF-like domain Cadherin_pro PF08758.11 KFP07511.1 - 1.8e-10 40.8 0.0 5.9e-05 23.2 0.0 6.8 8 0 0 8 8 8 1 Cadherin prodomain like RET_CLD1 PF17756.1 KFP07511.1 - 3.2e-09 37.1 0.9 0.66 10.3 0.0 7.9 9 0 0 9 9 8 1 RET Cadherin like domain 1 Cadherin_2 PF08266.12 KFP07511.1 - 5e-08 32.7 0.1 2.6 7.9 0.0 7.1 9 0 0 9 9 9 1 Cadherin-like hEGF PF12661.7 KFP07511.1 - 2.8e-07 30.9 37.4 0.0014 19.2 4.2 4.9 4 0 0 4 4 4 3 Human growth factor-like EGF Cadherin_3 PF16184.5 KFP07511.1 - 1.8e-06 27.9 12.8 4.3 7.4 0.1 8.7 8 0 0 8 8 8 1 Cadherin-like Y_Y_Y PF07495.13 KFP07511.1 - 3.8e-06 26.7 2.7 0.16 11.9 0.1 5.3 4 0 0 4 4 4 2 Y_Y_Y domain EGF_2 PF07974.13 KFP07511.1 - 9.5e-05 22.7 10.3 9.5e-05 22.7 10.3 4.2 4 0 0 4 4 3 2 EGF-like domain Big_3_4 PF13754.6 KFP07511.1 - 0.034 13.9 0.0 0.15 11.8 0.0 2.2 1 0 0 1 1 1 0 Domain of unknown function DUF1102 PF06510.11 KFP07511.1 - 0.3 11.3 1.7 23 5.2 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1102) He_PIG PF05345.12 KFP07511.1 - 3.6 7.8 18.9 0.2 11.8 0.3 5.7 7 0 0 7 7 5 0 Putative Ig domain TPR_2 PF07719.17 KFP07512.1 - 0.00062 19.7 5.2 0.25 11.5 0.3 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFP07512.1 - 0.011 15.4 1.1 0.77 9.5 0.1 2.8 2 0 0 2 2 2 0 TPR repeat TPR_7 PF13176.6 KFP07512.1 - 0.021 14.8 1.2 3.5 7.9 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFP07512.1 - 0.19 11.6 8.8 2.6 8.0 0.7 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFP07512.1 - 0.19 12.0 5.5 11 6.5 0.4 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP07512.1 - 0.28 11.4 2.4 1 9.7 0.2 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Zn_ribbon_2 PF12674.7 KFP07512.1 - 0.88 10.3 3.9 2.8 8.7 0.3 3.0 3 0 0 3 3 3 0 Putative zinc ribbon domain Cyclin_N PF00134.23 KFP07513.1 - 1.9e-40 137.6 1.1 4.2e-40 136.4 1.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP07513.1 - 7.7e-19 67.9 0.1 1.5e-18 67.0 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain DOR PF14839.6 KFP07514.1 - 5.3e-81 272.2 12.5 1.4e-80 270.9 12.5 1.6 1 1 0 1 1 1 1 DOR family SQS_PSY PF00494.19 KFP07515.1 - 3.9e-55 187.2 0.2 4.7e-55 186.9 0.2 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase PIN_3 PF13470.6 KFP07515.1 - 0.16 12.7 0.0 0.26 12.0 0.0 1.4 1 0 0 1 1 1 0 PIN domain FYVE PF01363.21 KFP07516.1 - 6.6e-19 67.8 7.4 1.5e-18 66.7 7.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 KFP07516.1 - 5.6e-11 42.9 0.4 2e-10 41.1 0.1 2.0 2 1 1 3 3 3 1 PH domain FYVE_2 PF02318.16 KFP07516.1 - 0.0012 19.1 5.4 0.0022 18.2 5.4 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger PH_13 PF16652.5 KFP07516.1 - 0.0038 17.0 0.7 0.11 12.3 0.7 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_16 PF17838.1 KFP07516.1 - 0.0062 16.4 0.1 0.027 14.3 0.1 1.9 1 1 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 KFP07516.1 - 0.026 14.5 0.1 0.052 13.5 0.1 1.5 1 0 0 1 1 1 0 PH domain DUF1835 PF08874.10 KFP07516.1 - 0.053 13.7 0.1 0.13 12.5 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1835) zf-HYPF PF07503.12 KFP07516.1 - 3.9 7.3 7.8 14 5.6 7.8 2.0 1 1 0 1 1 1 0 HypF finger zf-B_box PF00643.24 KFP07516.1 - 6 7.1 9.3 5.8 7.2 6.3 2.4 2 1 0 2 2 2 0 B-box zinc finger RMP PF14996.6 KFP07517.1 - 2.5e-53 180.4 6.1 2.8e-53 180.3 6.1 1.0 1 0 0 1 1 1 1 Retinal Maintenance UCR_14kD PF02271.16 KFP07518.1 - 1.5e-30 105.1 3.2 1.7e-30 104.9 3.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit mTERF PF02536.14 KFP07519.1 - 7e-27 94.2 0.5 9.3e-27 93.8 0.5 1.1 1 0 0 1 1 1 1 mTERF PSS PF03034.15 KFP07520.1 - 3.5e-105 351.7 23.8 3.5e-105 351.7 23.8 1.8 2 0 0 2 2 2 1 Phosphatidyl serine synthase Peptidase_C1 PF00112.23 KFP07520.1 - 0.11 12.6 0.1 0.2 11.7 0.1 1.3 1 0 0 1 1 1 0 Papain family cysteine protease Cyt_b-c1_8 PF10890.8 KFP07520.1 - 0.12 12.8 0.1 0.38 11.2 0.1 1.9 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 Syndecan PF01034.20 KFP07521.1 - 4.8e-30 103.3 0.0 9.2e-30 102.4 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain Peptidase_M50 PF02163.22 KFP07521.1 - 0.018 14.3 0.0 0.022 14.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M50 DUF1180 PF06679.12 KFP07521.1 - 0.019 15.4 0.0 0.028 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF2721 PF11026.8 KFP07521.1 - 0.021 14.7 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Glycophorin_A PF01102.18 KFP07521.1 - 0.028 14.6 3.2 0.078 13.2 3.2 1.8 1 1 0 1 1 1 0 Glycophorin A DUF2407_C PF13373.6 KFP07521.1 - 0.039 14.1 0.0 0.053 13.7 0.0 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain DUF2207 PF09972.9 KFP07521.1 - 0.041 12.7 0.0 0.044 12.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ATG22 PF11700.8 KFP07521.1 - 0.12 11.0 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like DUF4407 PF14362.6 KFP07521.1 - 0.13 11.6 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cadherin_C_2 PF16492.5 KFP07521.1 - 0.16 12.7 0.0 0.45 11.3 0.0 1.7 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal TGF_beta_GS PF08515.12 KFP07521.1 - 0.22 11.1 0.9 0.65 9.5 0.9 1.8 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif MtrF PF09472.10 KFP07521.1 - 0.41 10.1 2.9 0.67 9.4 2.9 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Glypican PF01153.19 KFP07521.1 - 0.48 9.2 2.9 0.6 8.9 2.9 1.1 1 0 0 1 1 1 0 Glypican PA PF02225.22 KFP07522.1 - 8.9e-05 22.4 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 PA domain F420_oxidored PF03807.17 KFP07522.1 - 0.062 13.9 0.4 2.5 8.8 0.0 2.5 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Peptidase_M28 PF04389.17 KFP07523.1 - 6.2e-24 84.8 0.0 7.1e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KFP07523.1 - 1.9e-08 34.3 0.0 2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 dbPDZ_assoc PF16610.5 KFP07523.1 - 0.083 13.1 0.0 0.19 12.0 0.0 1.5 2 0 0 2 2 2 0 Unstructured region between two PDZ domains on Dlg5 Mtp PF03821.16 KFP07524.1 - 6e-11 42.4 6.7 1.6e-06 27.9 2.7 2.1 1 1 1 2 2 2 2 Golgi 4-transmembrane spanning transporter Tetraspanin PF00335.20 KFP07524.1 - 0.0087 15.8 11.7 0.031 14.0 2.2 2.1 1 1 1 2 2 2 2 Tetraspanin family DUF4728 PF15860.5 KFP07524.1 - 0.019 15.6 0.9 0.019 15.6 0.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4728) Flp1_like PF16982.5 KFP07524.1 - 0.096 12.1 0.1 0.096 12.1 0.1 2.0 3 0 0 3 3 3 0 Putative Flagellin, Flp1-like, domain ABC2_membrane_2 PF12679.7 KFP07524.1 - 0.88 8.8 5.4 2.3 7.4 5.3 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein VWA PF00092.28 KFP07525.1 - 1e-100 335.2 0.3 5.8e-50 169.9 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain FXa_inhibition PF14670.6 KFP07525.1 - 3e-86 283.4 157.0 4e-10 39.8 7.1 10.6 11 0 0 11 11 11 10 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFP07525.1 - 1e-51 172.4 75.2 2.1e-06 27.5 1.6 10.8 10 1 0 10 10 10 10 Complement Clr-like EGF-like EGF_CA PF07645.15 KFP07525.1 - 8.8e-45 150.7 140.2 3.3e-06 27.2 6.9 10.5 10 0 0 10 10 10 10 Calcium-binding EGF domain VWA_2 PF13519.6 KFP07525.1 - 3.5e-37 127.3 0.2 8e-18 65.1 0.1 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain EGF PF00008.27 KFP07525.1 - 2.7e-27 94.7 129.3 0.00045 20.5 7.2 11.1 11 0 0 11 11 11 10 EGF-like domain hEGF PF12661.7 KFP07525.1 - 7.8e-16 58.0 101.3 0.00097 19.7 2.4 11.8 11 0 0 11 11 11 9 Human growth factor-like EGF EGF_3 PF12947.7 KFP07525.1 - 3.3e-14 52.8 148.3 0.0069 16.6 4.4 11.3 11 0 0 11 11 11 10 EGF domain Matrilin_ccoil PF10393.9 KFP07525.1 - 2e-09 37.2 0.8 2e-09 37.2 0.8 2.7 2 0 0 2 2 2 1 Trimeric coiled-coil oligomerisation domain of matrilin Sec23_trunk PF04811.15 KFP07525.1 - 6.8e-07 29.1 0.0 0.014 15.0 0.0 2.5 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain Plasmod_Pvs28 PF06247.11 KFP07525.1 - 1.8e-05 25.0 125.6 0.012 15.9 3.4 12.0 8 1 3 11 11 11 6 Pvs28 EGF domain Ribosomal_L7Ae PF01248.26 KFP07526.1 - 2.4e-08 33.6 0.0 2.9e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribonuc_L-PSP PF01042.21 KFP07527.1 - 8.7e-39 132.3 0.2 9.7e-39 132.1 0.2 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Corona_6B_7B PF03262.13 KFP07527.1 - 0.17 11.3 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Coronavirus 6B/7B protein POP1 PF06978.11 KFP07528.1 - 3.9e-37 128.3 28.9 4.6e-21 75.8 1.6 3.2 2 1 1 3 3 3 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KFP07528.1 - 8.6e-27 93.3 1.2 7.2e-26 90.4 0.1 2.7 2 0 0 2 2 2 1 POPLD (NUC188) domain EF-hand_3 PF09069.11 KFP07528.1 - 0.059 13.8 0.1 1.1 9.7 0.0 2.7 2 0 0 2 2 2 0 EF-hand Mg_trans_NIPA PF05653.14 KFP07529.1 - 4.4e-87 291.9 24.4 5.1e-87 291.7 24.4 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KFP07529.1 - 0.0017 18.5 0.6 0.0017 18.5 0.6 3.4 3 1 0 3 3 3 1 EamA-like transporter family Ion_trans PF00520.31 KFP07530.1 - 2.3e-41 141.6 4.3 2.3e-41 141.6 4.3 1.4 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.22 KFP07530.1 - 2.4e-31 107.9 0.2 3.7e-30 104.1 0.1 2.5 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFP07530.1 - 3.6e-13 49.3 3.5 3.6e-13 49.3 3.5 2.1 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.5 KFP07530.1 - 0.082 13.0 0.1 0.32 11.1 0.0 2.0 1 1 1 2 2 2 0 BTB/POZ domain DUF2463 PF09591.10 KFP07530.1 - 6.2 6.6 9.7 0.33 10.8 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2463) Pkinase PF00069.25 KFP07531.1 - 8.7e-72 241.6 0.0 1.5e-71 240.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP07531.1 - 7e-53 179.6 1.4 1.3e-52 178.7 0.0 2.0 3 0 0 3 3 3 1 Protein tyrosine kinase Mst1_SARAH PF11629.8 KFP07531.1 - 2.4e-25 88.3 5.1 2.4e-25 88.3 5.1 2.2 2 0 0 2 2 2 1 C terminal SARAH domain of Mst1 Pkinase_fungal PF17667.1 KFP07531.1 - 3e-06 26.3 2.0 3.2e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 KFP07531.1 - 0.0091 15.0 0.2 2.8 6.8 0.0 2.3 1 1 1 2 2 2 2 Haspin like kinase domain Abi_2 PF07751.11 KFP07531.1 - 0.051 13.8 0.0 0.051 13.8 0.0 2.1 2 1 0 2 2 2 0 Abi-like protein Selenoprotein_S PF06936.11 KFP07531.1 - 0.071 12.9 2.2 0.16 11.7 2.2 1.5 1 0 0 1 1 1 0 Selenoprotein S (SelS) Fib_succ_major PF09603.10 KFP07531.1 - 0.13 12.9 0.6 0.3 11.7 0.3 1.7 1 1 0 1 1 1 0 Fibrobacter succinogenes major domain (Fib_succ_major) Aldedh PF00171.22 KFP07532.1 - 1.2e-167 558.1 1.5 1.4e-167 558.0 1.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cecropin PF00272.19 KFP07532.1 - 0.083 12.6 0.3 0.3 10.8 0.3 2.0 1 0 0 1 1 1 0 Cecropin family Y_Y_Y PF07495.13 KFP07533.1 - 8e-16 57.8 0.0 0.0021 17.9 0.0 5.2 5 0 0 5 5 5 3 Y_Y_Y domain Big_9 PF17963.1 KFP07533.1 - 1.1e-12 48.5 14.8 0.0023 18.6 0.7 4.8 4 0 0 4 4 4 4 Bacterial Ig domain REJ PF02010.15 KFP07533.1 - 1.8e-12 46.8 3.3 5.9e-08 31.9 0.2 3.7 1 1 2 3 3 3 3 REJ domain PKD PF00801.20 KFP07533.1 - 3.8e-12 45.9 6.3 0.14 12.0 0.1 5.6 5 0 0 5 5 5 4 PKD domain DUF4625 PF15418.6 KFP07533.1 - 1.4e-07 31.8 0.1 3.6 7.8 0.0 4.5 4 0 0 4 4 4 3 Domain of unknown function (DUF4625) He_PIG PF05345.12 KFP07533.1 - 3.5e-06 27.1 3.4 3.8 7.8 0.1 5.6 5 0 0 5 5 5 1 Putative Ig domain DUF5013 PF16405.5 KFP07533.1 - 3.9e-05 24.0 1.2 0.25 11.6 0.1 4.6 4 1 1 5 5 5 1 Domain of unknown function (DUF5013) Wzt_C PF14524.6 KFP07533.1 - 0.00049 20.1 0.0 1.4 9.0 0.0 4.2 4 0 0 4 4 4 1 Wzt C-terminal domain MANEC PF07502.14 KFP07533.1 - 0.0032 17.7 5.6 0.0032 17.7 5.6 2.0 2 0 0 2 2 2 1 MANEC domain DUF4998 PF16389.5 KFP07533.1 - 0.005 16.4 3.3 9.3 5.8 0.0 4.5 5 0 0 5 5 5 1 Domain of unknown function DUF1180 PF06679.12 KFP07533.1 - 0.034 14.6 0.0 0.14 12.6 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF5011 PF16403.5 KFP07533.1 - 0.036 14.2 0.2 40 4.4 0.0 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF5011) Cadherin_5 PF17892.1 KFP07533.1 - 0.08 12.9 8.1 2 8.4 0.4 4.8 5 0 0 5 5 5 0 Cadherin-like domain DUF4388 PF14332.6 KFP07533.1 - 0.084 13.1 0.0 1 9.7 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4388) FixG_C PF11614.8 KFP07533.1 - 0.13 12.5 2.1 46 4.3 0.0 4.0 4 0 0 4 4 4 0 IG-like fold at C-terminal of FixG, putative oxidoreductase PAN_4 PF14295.6 KFP07533.1 - 0.29 11.1 5.8 0.36 10.8 3.5 2.2 2 0 0 2 2 2 0 PAN domain zf-C2H2 PF00096.26 KFP07534.1 - 3.1e-30 102.9 73.1 5.9e-05 23.3 0.2 10.0 10 0 0 10 10 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP07534.1 - 1.1e-29 100.5 75.9 0.00072 20.2 1.1 11.0 11 0 0 11 11 11 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP07534.1 - 2.1e-27 94.3 57.7 4.9e-07 29.9 1.1 11.0 11 0 0 11 11 11 7 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFP07534.1 - 2.1e-19 69.3 43.2 0.00095 19.4 1.0 9.9 10 0 0 10 10 10 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP07534.1 - 7.3e-19 67.5 59.5 0.0027 18.0 0.4 9.9 10 0 0 10 10 10 8 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KFP07534.1 - 0.00041 20.7 35.8 0.00084 19.7 3.1 6.6 5 2 1 6 6 6 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 KFP07534.1 - 0.00068 19.6 66.0 0.0075 16.3 1.6 10.0 10 0 0 10 10 10 5 C2H2-type zinc finger DUF3268 PF11672.8 KFP07534.1 - 0.002 18.4 17.7 0.17 12.2 0.8 4.3 4 0 0 4 4 4 2 zinc-finger-containing domain zf-Di19 PF05605.12 KFP07534.1 - 0.0063 16.8 34.8 0.076 13.3 2.6 5.0 4 1 0 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KFP07534.1 - 0.079 13.3 45.2 0.33 11.3 2.2 8.8 4 4 5 9 9 9 0 C2H2 type zinc-finger (2 copies) NinF PF05810.12 KFP07534.1 - 0.11 12.4 0.1 0.49 10.3 0.1 2.1 1 0 0 1 1 1 0 NinF protein BolA PF01722.18 KFP07534.1 - 0.35 11.2 5.2 17 5.8 0.1 3.8 3 0 0 3 3 3 0 BolA-like protein zf-C2H2_3rep PF18868.1 KFP07534.1 - 0.43 11.3 18.5 33 5.2 0.3 6.6 5 1 1 6 6 6 0 Zinc finger C2H2-type, 3 repeats DUF2225 PF09986.9 KFP07534.1 - 0.46 10.2 0.0 0.46 10.2 0.0 2.7 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) UPF1_Zn_bind PF09416.10 KFP07534.1 - 7.5 6.5 7.8 5.7 6.9 0.6 3.6 4 0 0 4 4 3 0 RNA helicase (UPF2 interacting domain) PhoLip_ATPase_C PF16212.5 KFP07535.1 - 1.1e-52 179.3 20.0 1.1e-52 179.3 20.0 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFP07535.1 - 5.2e-20 70.9 1.2 1.5e-19 69.4 1.2 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFP07535.1 - 4.5e-15 56.5 0.0 1.7e-12 48.1 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFP07535.1 - 1.3e-13 50.9 0.1 3.7e-13 49.4 0.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 KFP07535.1 - 7.3e-09 35.6 0.0 4.8e-08 33.0 0.0 2.3 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFP07535.1 - 0.00063 19.6 0.0 0.0018 18.1 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4174 PF13778.6 KFP07535.1 - 0.11 13.0 0.1 0.3 11.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) RHD_DNA_bind PF00554.22 KFP07536.1 - 1.8e-25 89.8 0.1 6.7e-25 88.0 0.1 2.0 1 1 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.5 KFP07536.1 - 3.8e-24 84.7 0.1 6.5e-24 83.9 0.1 1.4 1 0 0 1 1 1 1 Rel homology dimerisation domain TIG PF01833.24 KFP07536.1 - 1.5e-06 28.2 0.0 6.5e-06 26.1 0.0 2.2 1 0 0 1 1 1 1 IPT/TIG domain Ion_trans PF00520.31 KFP07537.1 - 3.6e-38 131.2 2.9 5e-38 130.7 2.9 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFP07537.1 - 2.3e-28 98.4 0.0 4.8e-28 97.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFP07537.1 - 2.4e-14 53.0 4.2 6.2e-14 51.7 1.5 2.5 2 0 0 2 2 2 1 Ion channel PQ-loop PF04193.14 KFP07538.1 - 2e-30 104.3 1.1 1.6e-19 69.4 0.1 3.8 3 1 1 4 4 4 2 PQ loop repeat ER_lumen_recept PF00810.18 KFP07538.1 - 0.00014 22.7 4.7 0.00057 20.7 4.0 2.2 1 1 1 2 2 2 2 ER lumen protein retaining receptor MtN3_slv PF03083.16 KFP07538.1 - 0.0022 18.0 6.0 0.051 13.6 1.2 2.6 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange DIM1 PF02966.16 KFP07539.1 - 6.8e-64 213.6 1.2 7.6e-64 213.4 1.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KFP07539.1 - 4e-06 26.8 0.1 5.1e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KFP07539.1 - 0.029 14.7 0.5 0.041 14.2 0.5 1.4 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_7 PF13899.6 KFP07539.1 - 0.057 13.6 0.0 0.099 12.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like 2-Hacid_dh_C PF02826.19 KFP07540.1 - 3e-59 199.4 0.0 4.6e-59 198.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFP07540.1 - 3.8e-19 68.7 0.0 4.2e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFP07540.1 - 2.5e-08 34.2 0.1 4.7e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 KFP07540.1 - 0.0028 17.8 0.1 0.31 11.1 0.0 2.4 3 0 0 3 3 3 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 KFP07540.1 - 0.013 15.1 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 KFP07540.1 - 0.014 14.7 0.0 0.074 12.3 0.0 2.1 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KFP07540.1 - 0.042 14.1 0.2 0.68 10.2 0.1 2.2 2 0 0 2 2 2 0 TrkA-N domain RBFA PF02033.18 KFP07541.1 - 0.00034 21.0 0.5 0.014 15.9 0.0 3.0 3 0 0 3 3 3 1 Ribosome-binding factor A Homeodomain PF00046.29 KFP07542.1 - 0.0001 22.1 0.0 0.00025 20.8 0.0 1.7 1 0 0 1 1 1 1 Homeodomain zf-C2H2_3rep PF18868.1 KFP07542.1 - 0.0014 19.3 1.9 0.0014 19.3 1.9 4.3 3 1 1 4 4 4 1 Zinc finger C2H2-type, 3 repeats PRP21_like_P PF12230.8 KFP07542.1 - 0.0056 16.6 0.3 0.49 10.2 0.1 2.5 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Zn-C2H2_12 PF18112.1 KFP07542.1 - 0.02 15.4 0.4 0.02 15.4 0.4 3.0 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain DUF2719 PF10891.8 KFP07542.1 - 0.22 11.4 6.4 0.45 10.4 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2719) zf_C2H2_ZHX PF18387.1 KFP07542.1 - 0.25 11.0 27.1 0.14 11.8 1.1 5.4 5 0 0 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_4 PF13894.6 KFP07542.1 - 0.49 11.4 69.2 0.073 14.0 0.8 9.8 10 0 0 10 10 10 0 C2H2-type zinc finger GAGA PF09237.11 KFP07542.1 - 0.86 9.5 4.2 28 4.6 0.0 3.6 4 0 0 4 4 4 0 GAGA factor Kazal_1 PF00050.21 KFP07543.1 - 1.2e-12 47.7 19.5 0.00052 20.0 2.7 5.0 2 1 1 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KFP07543.1 - 3e-11 43.3 38.5 5.4e-05 23.2 2.3 5.7 4 1 1 5 5 5 3 Kazal-type serine protease inhibitor domain Ldl_recept_a PF00057.18 KFP07543.1 - 0.0042 17.3 3.6 0.0042 17.3 3.6 6.9 5 1 1 6 6 6 1 Low-density lipoprotein receptor domain class A VWC PF00093.18 KFP07543.1 - 0.0065 16.8 4.0 0.0065 16.8 4.0 9.6 7 3 2 9 9 9 2 von Willebrand factor type C domain DNA_pol_E_B PF04042.16 KFP07543.1 - 0.022 14.1 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B Pkinase PF00069.25 KFP07544.1 - 4e-35 121.5 0.0 6.2e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP07544.1 - 3.7e-32 111.6 0.0 5.1e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.12 KFP07544.1 - 2.6e-17 62.0 0.4 4.9e-17 61.1 0.4 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.23 KFP07544.1 - 1.1e-08 36.1 8.4 1.1e-08 36.1 8.4 1.7 2 0 0 2 2 2 1 Activin types I and II receptor domain Pkinase_fungal PF17667.1 KFP07544.1 - 2.3e-05 23.4 0.5 0.00022 20.2 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFP07544.1 - 0.01 15.8 0.0 0.021 14.7 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFP07544.1 - 0.034 13.1 0.0 0.17 10.8 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain FTA2 PF13095.6 KFP07544.1 - 0.096 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 AAA PF00004.29 KFP07545.1 - 6e-31 107.6 0.0 9.3e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFP07545.1 - 4.5e-07 30.2 0.3 2.2e-06 28.0 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFP07545.1 - 5.5e-06 27.0 0.0 3.6e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFP07545.1 - 1.4e-05 25.5 0.0 2.9e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KFP07545.1 - 4.1e-05 23.6 0.0 8.9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KFP07545.1 - 0.00012 21.9 0.5 0.0027 17.5 0.0 2.5 2 1 0 2 2 2 1 Cytidylate kinase AAA_33 PF13671.6 KFP07545.1 - 0.0002 21.5 0.0 0.00036 20.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KFP07545.1 - 0.00054 19.7 0.0 0.0045 16.7 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 KFP07545.1 - 0.00077 19.1 0.1 0.1 12.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFP07545.1 - 0.00078 19.4 0.1 0.002 18.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 KFP07545.1 - 0.0012 18.8 0.8 1.1 9.1 0.0 2.4 1 1 1 2 2 2 2 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KFP07545.1 - 0.0014 18.4 0.0 0.0032 17.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 KFP07545.1 - 0.002 17.9 0.0 0.0046 16.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 KFP07545.1 - 0.0023 17.9 0.0 0.005 16.8 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KFP07545.1 - 0.0024 17.8 0.2 0.0099 15.8 0.2 2.1 1 1 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 KFP07545.1 - 0.0025 17.6 0.1 0.0059 16.3 0.1 1.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KFP07545.1 - 0.0025 18.2 0.0 0.0061 16.9 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 KFP07545.1 - 0.0027 18.0 0.0 0.0067 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 KFP07545.1 - 0.003 16.9 0.3 0.81 8.9 0.1 2.2 1 1 0 2 2 2 1 KAP family P-loop domain AAA_11 PF13086.6 KFP07545.1 - 0.0031 17.3 0.0 0.006 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KFP07545.1 - 0.0041 16.9 0.0 0.0084 15.9 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 KFP07545.1 - 0.0041 16.3 0.1 0.016 14.3 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 KFP07545.1 - 0.0042 16.6 0.0 0.014 14.9 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region PduV-EutP PF10662.9 KFP07545.1 - 0.0047 16.7 0.0 0.013 15.3 0.0 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 KFP07545.1 - 0.0048 17.4 0.1 0.013 16.1 0.0 1.8 2 0 0 2 2 1 1 ABC transporter TIP49 PF06068.13 KFP07545.1 - 0.0096 15.2 0.1 0.018 14.3 0.0 1.5 2 0 0 2 2 2 1 TIP49 P-loop domain ATPase PF06745.13 KFP07545.1 - 0.011 15.1 0.1 0.62 9.4 0.0 2.5 2 0 0 2 2 2 0 KaiC FtsK_SpoIIIE PF01580.18 KFP07545.1 - 0.013 14.8 0.1 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.6 KFP07545.1 - 0.021 15.2 0.0 0.053 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KFP07545.1 - 0.03 13.7 0.0 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KFP07545.1 - 0.039 14.3 0.0 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KFP07545.1 - 0.039 13.9 1.9 0.08 12.9 0.5 2.3 2 1 0 2 2 1 0 Rad17 P-loop domain PhoH PF02562.16 KFP07545.1 - 0.042 13.3 0.0 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_2 PF07724.14 KFP07545.1 - 0.048 13.8 0.0 0.097 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF2075 PF09848.9 KFP07545.1 - 0.073 12.3 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zot PF05707.12 KFP07545.1 - 0.1 12.2 0.3 2.1 7.9 0.3 2.3 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_3 PF07726.11 KFP07545.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3512 PF12024.8 KFP07546.1 - 5.6e-83 278.1 1.6 5.6e-83 278.1 1.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3512) Bromodomain PF00439.25 KFP07546.1 - 8.2e-25 86.7 0.1 1.5e-23 82.7 0.1 2.4 2 0 0 2 2 2 1 Bromodomain Zip PF02535.22 KFP07546.1 - 0.4 9.9 1.8 0.8 8.9 1.8 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 KFP07546.1 - 0.5 9.1 7.6 0.11 11.3 3.4 1.9 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 CPSF100_C PF13299.6 KFP07546.1 - 0.86 9.8 7.2 1 9.5 4.5 2.4 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.14 KFP07546.1 - 1.6 6.9 13.1 2.8 6.1 13.1 1.3 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.11 KFP07546.1 - 2.7 8.0 29.1 0.19 11.8 20.4 2.8 3 0 0 3 3 3 0 DNA-directed RNA polymerase I subunit RPA34.5 NARP1 PF12569.8 KFP07546.1 - 4 6.2 14.9 7.7 5.3 14.9 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 U79_P34 PF03064.16 KFP07546.1 - 6.4 6.1 22.3 13 5.1 22.3 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 p25-alpha PF05517.12 KFP07548.1 - 2.2e-67 226.1 5.4 2.5e-67 225.9 5.4 1.0 1 0 0 1 1 1 1 p25-alpha Rep_3 PF01051.21 KFP07548.1 - 0.028 14.3 0.3 0.035 13.9 0.3 1.1 1 0 0 1 1 1 0 Initiator Replication protein T3SchapCesA PF11439.8 KFP07548.1 - 0.043 14.0 0.2 0.065 13.4 0.2 1.4 1 0 0 1 1 1 0 Type III secretion system filament chaperone CesA Drf_FH3 PF06367.16 KFP07548.1 - 0.074 12.7 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 Diaphanous FH3 Domain HGD-D PF06050.13 KFP07548.1 - 0.093 12.5 0.0 0.1 12.4 0.0 1.0 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component Na_H_Exchanger PF00999.21 KFP07549.1 - 3.5e-84 282.8 45.0 4e-84 282.6 45.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CxC2 PF18803.1 KFP07550.1 - 3e-05 24.1 0.1 9.2e-05 22.6 0.1 1.8 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases LRR_6 PF13516.6 KFP07550.1 - 0.034 14.2 10.0 0.85 9.8 0.1 5.5 6 0 0 6 6 6 0 Leucine Rich repeat PPIP5K2_N PF18086.1 KFP07550.1 - 0.11 12.7 0.2 25 5.1 0.1 2.9 2 0 0 2 2 2 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain LRR_1 PF00560.33 KFP07550.1 - 0.15 12.7 9.1 39 5.3 0.2 5.9 4 1 0 4 4 4 0 Leucine Rich Repeat AA_permease PF00324.21 KFP07551.1 - 7.6e-51 173.2 20.2 4.7e-40 137.6 7.3 2.1 2 0 0 2 2 2 2 Amino acid permease SLC12 PF03522.15 KFP07551.1 - 9.1e-47 160.0 7.6 6.5e-17 61.7 2.1 3.2 2 1 1 3 3 3 3 Solute carrier family 12 R3H PF01424.22 KFP07552.1 - 2.6e-18 65.7 0.1 4.9e-18 64.9 0.1 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 KFP07552.1 - 1.4e-10 41.1 76.7 2.2e-05 24.4 11.7 13.5 13 1 0 13 13 13 7 NF-X1 type zinc finger Laminin_II PF06009.12 KFP07553.1 - 0.092 12.8 0.1 0.094 12.7 0.1 1.2 1 0 0 1 1 1 0 Laminin Domain II DUF5087 PF17006.5 KFP07555.1 - 0.0018 17.9 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5087) PTB PF08416.13 KFP07556.1 - 7.5e-40 136.1 0.0 1.4e-39 135.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH2 PF00017.24 KFP07556.1 - 8e-10 38.7 0.0 2.3e-09 37.2 0.0 1.9 1 0 0 1 1 1 1 SH2 domain PTEN_C2 PF10409.9 KFP07556.1 - 4.9e-09 36.1 0.0 1.9e-08 34.1 0.0 2.1 1 1 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Y_phosphatase PF00102.27 KFP07556.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase TPX2_importin PF12214.8 KFP07556.1 - 0.092 12.9 0.2 0.19 11.9 0.2 1.4 1 0 0 1 1 1 0 Cell cycle regulated microtubule associated protein Y_phosphatase3 PF13350.6 KFP07556.1 - 0.098 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family YhfZ_C PF14503.6 KFP07556.1 - 0.21 11.1 0.0 5.5 6.5 0.0 2.3 2 0 0 2 2 2 0 YhfZ C-terminal domain Thyroglobulin_1 PF00086.18 KFP07557.1 - 1e-19 69.9 3.5 2.1e-19 68.9 3.5 1.6 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat DUF4829 PF16111.5 KFP07557.1 - 0.0055 17.5 0.3 0.0085 16.9 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4829) Glycos_transf_2 PF00535.26 KFP07558.1 - 1.6e-08 34.6 0.0 2.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF4462 PF14692.6 KFP07559.1 - 0.19 11.2 0.1 0.29 10.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Ricin_B_lectin PF00652.22 KFP07560.1 - 2.4e-25 89.2 0.6 3.2e-25 88.8 0.6 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glycos_transf_2 PF00535.26 KFP07560.1 - 1.3e-16 60.9 0.0 2.4e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 KFP07560.1 - 7.7e-06 25.5 0.3 1.8e-05 24.3 0.3 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KFP07560.1 - 0.0052 16.3 0.0 0.037 13.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KFP07561.1 - 2.8e-25 89.1 0.0 4.6e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFP07561.1 - 6e-23 81.5 0.9 1.1e-22 80.6 0.9 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 KFP07561.1 - 0.00056 19.9 0.0 0.001 19.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KFP07561.1 - 0.00069 19.2 0.0 0.0018 17.9 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KFP07561.1 - 0.014 14.9 0.2 0.14 11.6 0.2 2.3 1 1 0 1 1 1 0 Glycosyltransferase like family 2 HMG_box_2 PF09011.10 KFP07562.1 - 1.4e-42 144.1 14.3 4.3e-27 94.5 6.5 2.3 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 KFP07562.1 - 8.3e-41 138.3 12.6 1.1e-25 89.8 1.5 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_5 PF14887.6 KFP07562.1 - 0.0048 16.8 11.6 0.29 11.1 2.9 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box 5 DUF1244 PF06844.11 KFP07562.1 - 0.8 9.9 3.7 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1244) YABBY PF04690.13 KFP07562.1 - 2 9.0 6.4 0.29 11.7 1.2 2.0 1 1 1 2 2 2 0 YABBY protein SAP30_Sin3_bdg PF13867.6 KFP07563.1 - 2.5e-23 82.1 0.1 3.9e-23 81.5 0.1 1.3 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 zf-SAP30 PF13866.6 KFP07563.1 - 2.6e-13 49.9 1.3 6.1e-13 48.7 1.2 1.7 2 0 0 2 2 2 1 SAP30 zinc-finger SCRG1 PF15224.6 KFP07565.1 - 1.9e-46 156.1 5.1 2.2e-46 155.8 5.1 1.0 1 0 0 1 1 1 1 Scrapie-responsive protein 1 HLH PF00010.26 KFP07566.1 - 4.9e-19 68.0 0.5 4.9e-19 68.0 0.5 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain HTH_51 PF18558.1 KFP07566.1 - 0.046 13.6 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain EDS1_EP PF18117.1 KFP07566.1 - 0.073 13.5 0.2 0.15 12.6 0.2 1.5 1 0 0 1 1 1 0 Enhanced disease susceptibility 1 protein EP domain Sec7 PF01369.20 KFP07567.1 - 1.1e-39 136.1 0.1 1.5e-39 135.6 0.1 1.1 1 0 0 1 1 1 1 Sec7 domain F-box-like PF12937.7 KFP07567.1 - 3.2e-07 30.1 0.5 8.4e-07 28.8 0.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFP07567.1 - 0.0046 16.8 1.3 0.0085 16.0 0.2 2.0 2 0 0 2 2 2 1 F-box domain PRANC PF09372.10 KFP07567.1 - 0.13 12.6 0.0 0.46 10.8 0.0 2.0 2 0 0 2 2 2 0 PRANC domain CEP44 PF15007.6 KFP07568.1 - 1.7e-52 176.9 0.3 4.8e-52 175.4 0.3 1.8 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 adh_short PF00106.25 KFP07569.1 - 2.4e-46 157.7 0.0 3.5e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP07569.1 - 9.9e-39 133.3 0.0 1.2e-38 133.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP07569.1 - 3.4e-07 30.4 0.0 4.5e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFP07569.1 - 0.018 14.5 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Neur_chan_LBD PF02931.23 KFP07570.1 - 8.4e-52 175.7 0.1 1.2e-51 175.2 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP07570.1 - 8.2e-38 130.8 6.0 5e-33 115.1 2.2 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF4227 PF14004.6 KFP07570.1 - 0.32 11.0 0.0 0.32 11.0 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4227) Myelin_PLP PF01275.19 KFP07572.1 - 5.8e-92 307.8 24.0 6.6e-92 307.6 24.0 1.0 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) DUF2701 PF10857.8 KFP07572.1 - 0.1 12.6 2.1 0.33 11.0 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2701) WD40 PF00400.32 KFP07573.1 - 5.9e-33 112.4 35.4 2.5e-06 28.1 0.1 10.5 12 0 0 12 12 12 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP07573.1 - 3.9e-22 78.4 0.2 6.9e-05 23.1 0.0 6.5 3 2 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP07573.1 - 0.0021 16.8 4.7 0.52 8.9 0.0 4.5 5 1 1 6 6 6 2 Nucleoporin Nup120/160 Ank_4 PF13637.6 KFP07574.1 - 5.7e-33 112.9 1.2 1.7e-10 41.2 0.1 5.1 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP07574.1 - 1.2e-32 112.4 0.6 3.5e-15 56.3 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP07574.1 - 1.3e-28 95.8 4.0 2.4e-05 24.4 0.0 7.5 7 1 1 8 8 8 6 Ankyrin repeat Ank PF00023.30 KFP07574.1 - 1.8e-28 97.7 6.9 1.7e-06 28.2 0.1 6.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KFP07574.1 - 2.2e-22 78.8 3.7 9.3e-07 29.0 0.1 6.0 1 1 5 6 6 6 4 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFP07574.1 - 2.2e-10 40.7 7.5 4.3e-10 39.8 6.4 2.0 2 0 0 2 2 2 1 SOCS box SPC22 PF04573.12 KFP07575.1 - 3.1e-42 144.0 0.0 3.8e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Signal peptidase subunit CBM_3 PF00942.18 KFP07575.1 - 0.064 13.7 0.0 0.08 13.4 0.0 1.3 1 0 0 1 1 1 0 Cellulose binding domain Pyr_redox_2 PF07992.14 KFP07576.1 - 2.9e-23 82.6 0.0 5.1e-11 42.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 KFP07576.1 - 1.5e-07 31.2 0.2 6.9e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox_3 PF13738.6 KFP07576.1 - 0.0032 16.8 0.2 0.39 9.9 0.0 3.1 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_S9 PF00380.19 KFP07577.1 - 1.9e-32 112.3 0.1 2.2e-32 112.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 PRKG1_interact PF15898.5 KFP07578.1 - 2.2e-33 115.2 14.6 2.2e-33 115.2 14.6 6.0 5 2 0 5 5 5 1 cGMP-dependent protein kinase interacting domain Ank_4 PF13637.6 KFP07578.1 - 1.9e-28 98.4 0.7 2.1e-11 44.1 0.1 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP07578.1 - 1.8e-27 95.8 0.5 3.1e-13 50.1 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP07578.1 - 3.3e-23 81.5 3.6 3.4e-07 30.4 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KFP07578.1 - 6.7e-20 70.6 0.6 0.0031 17.9 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KFP07578.1 - 2.4e-16 58.2 2.3 0.0084 16.5 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat C2 PF00168.30 KFP07579.1 - 7e-55 183.7 0.5 8.9e-27 93.4 0.0 2.3 2 0 0 2 2 2 2 C2 domain Comm PF15957.5 KFP07579.1 - 0.0018 18.6 0.0 0.0051 17.2 0.0 1.7 1 0 0 1 1 1 1 Commissureless CEP76-C2 PF15627.6 KFP07579.1 - 0.002 17.7 0.0 1 8.9 0.0 2.3 1 1 1 2 2 2 2 CEP76 C2 domain MAP17 PF15807.5 KFP07579.1 - 0.0085 16.3 0.1 0.021 15.1 0.1 1.6 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Shisa PF13908.6 KFP07579.1 - 0.037 14.3 0.0 0.063 13.5 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF1258 PF06869.12 KFP07579.1 - 0.054 13.0 0.4 0.1 12.0 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) PAG PF15347.6 KFP07579.1 - 0.066 12.2 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched DOCK-C2 PF14429.6 KFP07579.1 - 0.073 12.9 0.3 7.1 6.4 0.0 2.2 2 0 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins EphA2_TM PF14575.6 KFP07579.1 - 0.079 13.8 0.0 0.19 12.7 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain E2F_TDP PF02319.20 KFP07581.1 - 5.3e-43 144.9 1.6 3.3e-21 75.1 0.0 2.4 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 KFP07581.1 - 0.00016 21.4 0.1 0.0014 18.5 0.1 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.12 KFP07581.1 - 0.00026 21.1 0.0 0.69 10.1 0.0 2.5 2 0 0 2 2 2 2 B-block binding subunit of TFIIIC Cdc6_C PF09079.11 KFP07581.1 - 0.035 14.1 0.0 2.7 8.0 0.0 2.4 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain DHHC PF01529.20 KFP07582.1 - 1.5e-35 122.2 21.0 1.5e-35 122.2 21.0 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.6 KFP07582.1 - 2.7e-32 110.7 6.0 8e-09 35.9 0.0 4.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP07582.1 - 8.5e-31 106.4 0.2 3.6e-16 59.5 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP07582.1 - 6.9e-29 99.5 2.1 6.6e-07 29.5 0.2 5.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP07582.1 - 1.1e-28 96.1 1.5 4.6e-05 23.5 0.1 7.5 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 KFP07582.1 - 2.5e-23 81.5 2.3 5.6e-06 26.6 0.4 6.0 6 0 0 6 6 6 5 Ankyrin repeat Oxysterol_BP PF01237.18 KFP07583.1 - 9.3e-95 317.6 4.9 2.5e-92 309.6 4.9 2.5 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 KFP07583.1 - 3.4e-10 40.4 0.0 1.2e-09 38.6 0.0 2.0 1 0 0 1 1 1 1 PH domain Cpn60_TCP1 PF00118.24 KFP07584.1 - 2.1e-05 23.4 0.0 0.15 10.7 0.0 2.2 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family NAP PF00956.18 KFP07585.1 - 4.4e-114 380.2 6.9 4.4e-114 380.2 6.9 1.4 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) sCache_3_3 PF17202.4 KFP07585.1 - 0.061 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Single cache domain 3 ING PF12998.7 KFP07585.1 - 0.079 13.6 1.8 0.41 11.3 1.8 2.1 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding GEN1_C PF18380.1 KFP07585.1 - 4.4 8.2 12.4 1.9 9.4 3.5 2.4 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain KH_8 PF17903.1 KFP07586.1 - 2.9e-31 107.4 0.0 2.9e-31 107.4 0.0 2.3 3 0 0 3 3 3 1 Krr1 KH1 domain KH_1 PF00013.29 KFP07586.1 - 0.00015 21.6 0.7 0.0015 18.3 0.0 2.6 3 0 0 3 3 3 1 KH domain KH_4 PF13083.6 KFP07586.1 - 0.041 13.8 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 KH domain CAP PF00188.26 KFP07587.1 - 1.7e-24 87.0 3.9 2.1e-24 86.7 3.9 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Keratin PF02422.16 KFP07589.1 - 3e-35 119.8 10.8 3.3e-35 119.7 10.8 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFP07590.1 - 1.8e-33 114.1 18.8 2.3e-33 113.8 9.9 2.1 1 1 1 2 2 2 2 Keratin DUF3432 PF11914.8 KFP07590.1 - 0.3 11.3 8.0 0.43 10.8 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Collagen PF01391.18 KFP07590.1 - 0.57 10.0 22.6 0.19 11.5 20.0 1.5 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Keratin PF02422.16 KFP07591.1 - 1.8e-33 114.1 18.8 2.3e-33 113.8 9.9 2.1 1 1 1 2 2 2 2 Keratin DUF3432 PF11914.8 KFP07591.1 - 0.3 11.3 8.0 0.43 10.8 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Collagen PF01391.18 KFP07591.1 - 0.57 10.0 22.6 0.19 11.5 20.0 1.5 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Keratin PF02422.16 KFP07592.1 - 6.3e-37 125.2 14.5 7e-37 125.0 14.5 1.0 1 0 0 1 1 1 1 Keratin TIL PF01826.17 KFP07592.1 - 0.038 14.3 5.7 0.047 13.9 5.7 1.2 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Keratin PF02422.16 KFP07593.1 - 2.6e-38 129.6 15.3 2.9e-38 129.5 15.3 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFP07595.1 - 2.6e-37 126.4 13.3 2.9e-37 126.3 13.3 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFP07596.1 - 9.2e-38 127.8 14.8 1e-37 127.7 14.8 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFP07598.1 - 4.7e-39 132.0 10.1 5.1e-39 131.9 10.1 1.0 1 0 0 1 1 1 1 Keratin CALCOCO1 PF07888.11 KFP07598.1 - 0.097 11.5 0.1 0.1 11.4 0.1 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Keratin PF02422.16 KFP07600.1 - 3.4e-40 135.7 10.2 3.6e-40 135.6 10.2 1.0 1 0 0 1 1 1 1 Keratin CALCOCO1 PF07888.11 KFP07600.1 - 0.12 11.3 0.1 0.12 11.2 0.1 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Keratin PF02422.16 KFP07601.1 - 2.9e-37 126.3 11.1 3.1e-37 126.2 11.1 1.0 1 0 0 1 1 1 1 Keratin CALCOCO1 PF07888.11 KFP07601.1 - 0.087 11.7 0.2 0.089 11.6 0.2 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Keratin PF02422.16 KFP07602.1 - 3.4e-40 135.7 10.2 3.6e-40 135.6 10.2 1.0 1 0 0 1 1 1 1 Keratin CALCOCO1 PF07888.11 KFP07602.1 - 0.12 11.3 0.1 0.12 11.2 0.1 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Keratin PF02422.16 KFP07604.1 - 3.4e-40 135.7 10.2 3.6e-40 135.6 10.2 1.0 1 0 0 1 1 1 1 Keratin CALCOCO1 PF07888.11 KFP07604.1 - 0.12 11.3 0.1 0.12 11.2 0.1 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Keratin PF02422.16 KFP07606.1 - 3.4e-40 135.7 10.2 3.6e-40 135.6 10.2 1.0 1 0 0 1 1 1 1 Keratin CALCOCO1 PF07888.11 KFP07606.1 - 0.12 11.3 0.1 0.12 11.2 0.1 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Keratin PF02422.16 KFP07608.1 - 3.4e-40 135.7 10.2 3.6e-40 135.6 10.2 1.0 1 0 0 1 1 1 1 Keratin CALCOCO1 PF07888.11 KFP07608.1 - 0.12 11.3 0.1 0.12 11.2 0.1 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Keratin PF02422.16 KFP07609.1 - 3.8e-17 61.8 2.3 4.2e-17 61.6 2.3 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFP07610.1 - 7e-29 99.4 11.6 7.4e-29 99.3 11.6 1.0 1 0 0 1 1 1 1 Keratin Cornifin PF02389.15 KFP07610.1 - 0.016 15.4 8.7 0.018 15.2 8.7 1.0 1 0 0 1 1 1 0 Cornifin (SPRR) family TMEM171 PF15471.6 KFP07610.1 - 0.037 13.0 1.9 0.036 13.1 1.9 1.0 1 0 0 1 1 1 0 Transmembrane protein family 171 DUF3432 PF11914.8 KFP07610.1 - 0.067 13.4 6.2 0.12 12.6 6.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.16 KFP07611.1 - 6.6e-34 115.5 12.6 7.2e-34 115.4 12.6 1.0 1 0 0 1 1 1 1 Keratin Fer4_3 PF12798.7 KFP07611.1 - 2 9.6 8.9 3.4 8.8 0.9 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Defensin_like PF10868.8 KFP07611.1 - 7.5 7.4 7.4 3.3 8.5 1.3 2.2 1 1 1 2 2 2 0 Cysteine-rich antifungal protein 2, defensin-like Keratin PF02422.16 KFP07612.1 - 8.5e-38 128.0 11.9 9.4e-38 127.8 11.9 1.0 1 0 0 1 1 1 1 Keratin TIL PF01826.17 KFP07612.1 - 0.038 14.2 4.6 0.049 13.9 4.6 1.1 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Defensin_like PF10868.8 KFP07612.1 - 4 8.3 6.6 26 5.7 6.6 2.0 1 1 0 1 1 1 0 Cysteine-rich antifungal protein 2, defensin-like Fer4_3 PF12798.7 KFP07612.1 - 7.4 7.8 10.3 6 8.1 1.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Keratin PF02422.16 KFP07613.1 - 3.9e-28 97.0 11.2 4.2e-28 96.9 11.2 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.8 KFP07613.1 - 0.032 14.5 2.7 0.041 14.1 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) S_100 PF01023.19 KFP07614.1 - 6.7e-18 64.1 0.6 9.5e-18 63.6 0.6 1.2 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.32 KFP07614.1 - 0.00036 19.9 1.0 0.0018 17.7 0.2 2.3 2 0 0 2 2 2 1 EF hand DEK_C PF08766.11 KFP07614.1 - 0.0011 18.9 1.6 0.0023 17.8 1.6 1.5 1 0 0 1 1 1 1 DEK C terminal domain EF-hand_7 PF13499.6 KFP07614.1 - 0.0021 18.4 0.7 0.0077 16.7 0.7 1.9 1 1 0 1 1 1 1 EF-hand domain pair S_100 PF01023.19 KFP07615.1 - 1.3e-19 69.5 0.5 1.3e-19 69.5 0.5 1.8 3 0 0 3 3 3 1 S-100/ICaBP type calcium binding domain EF-hand_7 PF13499.6 KFP07615.1 - 1.1e-05 25.7 0.2 1.5e-05 25.3 0.2 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP07615.1 - 0.00032 20.0 0.4 0.015 14.8 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KFP07615.1 - 0.013 15.4 0.0 6.8 6.9 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain EF-hand_9 PF14658.6 KFP07615.1 - 0.048 14.0 0.1 0.08 13.3 0.1 1.4 1 0 0 1 1 1 0 EF-hand domain S_100 PF01023.19 KFP07616.1 - 1e-19 70.0 1.8 2.6e-18 65.4 0.4 2.2 2 0 0 2 2 2 1 S-100/ICaBP type calcium binding domain EF-hand_7 PF13499.6 KFP07616.1 - 0.00047 20.5 1.1 0.00084 19.8 1.1 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP07616.1 - 0.0032 16.9 0.4 0.0032 16.9 0.4 2.8 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 KFP07616.1 - 0.011 15.6 4.6 0.51 10.4 0.2 3.1 1 1 3 4 4 4 0 EF-hand domain DUF5482 PF17579.2 KFP07616.1 - 0.029 14.2 0.0 0.032 14.1 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5482) EF-hand_4 PF12763.7 KFP07616.1 - 0.062 13.3 0.0 0.068 13.1 0.0 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Evf PF18270.1 KFP07616.1 - 0.092 12.2 0.0 0.094 12.1 0.0 1.1 1 0 0 1 1 1 0 Virulence factor Evf S_100 PF01023.19 KFP07617.1 - 8.2e-12 44.6 0.0 1.2e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_5 PF13202.6 KFP07617.1 - 1.2e-06 27.8 1.1 0.00024 20.4 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 KFP07617.1 - 4.7e-06 25.8 0.4 0.0014 18.1 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFP07617.1 - 2.5e-05 24.6 0.2 0.0001 22.6 0.2 1.8 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP07617.1 - 0.0022 17.8 0.1 1 9.5 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KFP07617.1 - 0.0023 17.7 0.8 0.0062 16.4 0.3 1.9 2 1 0 2 2 2 1 EF-hand domain pair DUF5532 PF17673.1 KFP07617.1 - 0.01 15.9 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5532) UL11 PF11094.8 KFP07617.1 - 4.6 7.2 5.9 3.9 7.4 3.3 2.0 2 0 0 2 2 2 0 Membrane-associated tegument protein S_100 PF01023.19 KFP07618.1 - 1.4e-09 37.5 0.5 2.4e-09 36.7 0.0 1.7 2 0 0 2 2 2 1 S-100/ICaBP type calcium binding domain S_100 PF01023.19 KFP07619.1 - 1.9e-14 53.1 0.2 3.2e-14 52.4 0.2 1.4 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.32 KFP07619.1 - 0.0089 15.5 0.3 7.5 6.4 0.0 2.9 3 0 0 3 3 3 2 EF hand TPR_15 PF13429.6 KFP07619.1 - 0.022 14.0 0.0 0.026 13.7 0.0 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat VasL PF12486.8 KFP07619.1 - 0.054 13.4 0.0 0.071 13.0 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, EvfB, or VasL EF-hand_7 PF13499.6 KFP07619.1 - 0.064 13.7 0.3 0.15 12.5 0.3 1.8 1 1 0 1 1 1 0 EF-hand domain pair S_100 PF01023.19 KFP07620.1 - 8.6e-23 79.8 1.5 9.7e-23 79.6 1.5 1.1 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain FoP_duplication PF13865.6 KFP07621.1 - 3e-22 79.0 13.2 3e-22 79.0 13.2 3.7 1 1 2 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Sbi-IV PF11621.8 KFP07621.1 - 0.46 10.9 9.9 6.9 7.1 0.0 3.9 2 2 2 4 4 4 0 C3 binding domain 4 of IgG-bind protein SBI Snapin_Pallidin PF14712.6 KFP07622.1 - 1.8e-17 63.6 3.2 2.2e-17 63.3 3.2 1.1 1 0 0 1 1 1 1 Snapin/Pallidin DUF4686 PF15742.5 KFP07622.1 - 0.05 12.7 2.5 0.057 12.6 2.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) Guanylate_cyc PF00211.20 KFP07623.1 - 3.3e-39 134.4 0.0 1.7e-37 128.8 0.0 2.1 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KFP07623.1 - 1.9e-05 24.2 1.2 2.8e-05 23.7 1.2 1.2 1 0 0 1 1 1 1 Heme NO binding associated Pkinase_Tyr PF07714.17 KFP07623.1 - 0.0004 19.8 0.0 0.0007 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DIRP PF06584.13 KFP07623.1 - 0.016 15.4 0.4 0.027 14.7 0.4 1.3 1 0 0 1 1 1 0 DIRP YtxC PF08812.11 KFP07623.1 - 0.017 14.8 0.3 0.023 14.3 0.3 1.2 1 0 0 1 1 1 0 YtxC-like family CHASE6_C PF17150.4 KFP07623.1 - 0.042 14.5 0.2 0.071 13.8 0.2 1.4 1 0 0 1 1 1 0 C-terminal domain of two-partite extracellular sensor domain RVT_1 PF00078.27 KFP07624.1 - 1.8e-16 60.4 0.0 2.4e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFP07624.1 - 2.1e-05 24.5 0.0 3.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RhoGAP PF00620.27 KFP07625.1 - 6.8e-43 146.1 0.0 1.3e-42 145.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 KFP07625.1 - 2e-07 30.8 3.0 3.9e-07 29.9 3.0 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) TonB_2 PF13103.6 KFP07625.1 - 0.0086 16.3 0.1 0.028 14.7 0.1 1.9 1 0 0 1 1 1 1 TonB C terminal zf-C4H2 PF10146.9 KFP07625.1 - 0.019 15.3 0.5 0.019 15.3 0.5 1.9 2 1 0 2 2 2 0 Zinc finger-containing protein SPATA1_C PF15743.5 KFP07625.1 - 0.053 13.6 3.5 0.13 12.3 3.5 1.7 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus APC_N_CC PF16689.5 KFP07625.1 - 0.12 12.5 4.0 0.35 10.9 2.4 2.3 1 1 1 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Cep57_CLD PF14073.6 KFP07625.1 - 0.16 12.0 7.9 0.41 10.7 7.8 1.7 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 zf-CCHC_6 PF15288.6 KFP07625.1 - 0.21 11.4 2.4 0.59 10.0 2.4 1.8 1 0 0 1 1 1 0 Zinc knuckle DUF2968 PF11180.8 KFP07625.1 - 0.32 10.6 6.6 0.52 9.9 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) ASC PF00858.24 KFP07626.1 - 1.5e-111 373.6 0.6 1.7e-111 373.3 0.6 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DUF4074 PF13293.6 KFP07626.1 - 0.67 10.3 3.0 0.32 11.3 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4074) SWIB PF02201.18 KFP07627.1 - 6.5e-25 86.8 0.2 1.6e-24 85.5 0.2 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain NAD_Gly3P_dh_C PF07479.14 KFP07628.1 - 7.4e-51 172.2 0.1 1.5e-50 171.2 0.1 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KFP07628.1 - 4.8e-47 159.8 0.0 1.3e-46 158.4 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GerD PF17898.1 KFP07628.1 - 0.0044 16.9 0.0 0.081 12.9 0.0 2.2 2 0 0 2 2 2 1 Spore germination GerD central core domain DUF643 PF04867.12 KFP07628.1 - 0.078 13.6 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF643) TRAM_LAG1_CLN8 PF03798.16 KFP07629.1 - 2.6e-41 141.5 29.1 3.1e-41 141.3 29.1 1.1 1 0 0 1 1 1 1 TLC domain Homeodomain PF00046.29 KFP07629.1 - 1.7e-07 31.0 0.2 2.9e-07 30.2 0.2 1.4 1 0 0 1 1 1 1 Homeodomain LIM PF00412.22 KFP07630.1 - 1.3e-06 28.6 3.9 2.4e-06 27.7 3.9 1.5 1 0 0 1 1 1 1 LIM domain HCO3_cotransp PF00955.21 KFP07631.1 - 2.9e-113 379.4 4.2 3.5e-113 379.1 4.2 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 KFP07631.1 - 8.3e-99 330.7 0.0 1.3e-98 330.1 0.0 1.3 1 0 0 1 1 1 1 Band 3 cytoplasmic domain ANAPC4 PF12896.7 KFP07631.1 - 0.19 11.2 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 Tetraspanin PF00335.20 KFP07632.1 - 4.7e-46 157.4 6.6 5.5e-46 157.1 6.6 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF5592 PF17332.2 KFP07632.1 - 0.95 10.1 4.9 0.34 11.5 0.4 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5592) DUF2371 PF10177.9 KFP07632.1 - 5.6 7.1 5.4 53 4.0 3.3 2.7 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) 7tm_1 PF00001.21 KFP07633.1 - 6.7e-55 186.2 21.7 8.9e-55 185.8 21.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP07633.1 - 4.4e-06 26.3 21.1 6e-06 25.8 21.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP07633.1 - 0.00032 20.5 18.1 0.0016 18.2 18.1 2.1 1 1 0 1 1 1 1 Olfactory receptor Cnd2 PF05786.14 KFP07634.1 - 1.5e-14 53.7 0.0 1.5e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 RVT_1 PF00078.27 KFP07635.1 - 0.033 13.7 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) SKA2 PF16740.5 KFP07636.1 - 0.016 15.0 4.8 0.016 15.0 4.8 6.9 3 3 5 8 8 8 0 Spindle and kinetochore-associated protein 2 Cep57_CLD_2 PF14197.6 KFP07637.1 - 0.023 14.8 3.9 0.023 14.8 3.9 8.0 1 1 6 7 7 7 0 Centrosome localisation domain of PPC89 Asp4 PF16996.5 KFP07637.1 - 4.8 7.0 5.5 11 5.8 2.1 2.7 2 0 0 2 2 2 0 Accessory secretory protein Sec Asp4 MBD_C PF14048.6 KFP07638.1 - 5.4e-24 84.7 0.0 6.5e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 C-terminal domain of methyl-CpG binding protein 2 and 3 MBDa PF16564.5 KFP07638.1 - 0.028 14.6 0.2 0.046 13.9 0.2 1.4 1 0 0 1 1 1 0 p55-binding region of Methyl-CpG-binding domain proteins MBD Pardaxin PF07425.11 KFP07638.1 - 0.029 14.0 0.6 0.079 12.6 0.6 1.7 1 0 0 1 1 1 0 Pardaxin zf-H2C2_2 PF13465.6 KFP07639.1 - 5e-19 67.8 33.2 4.8e-08 33.1 2.8 6.5 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFP07639.1 - 5.7e-16 58.0 47.0 6.5e-05 23.2 1.3 6.4 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP07639.1 - 1.2e-11 44.4 42.2 0.00072 20.2 1.1 6.4 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFP07639.1 - 2.3e-05 24.0 32.0 0.0011 18.6 1.1 4.8 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFP07639.1 - 0.037 14.3 26.3 0.73 10.2 0.0 5.4 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFP07639.1 - 0.095 12.5 0.3 0.095 12.5 0.3 4.6 6 0 0 6 6 6 0 zinc-finger C2H2-type GAGA PF09237.11 KFP07639.1 - 0.12 12.2 0.1 0.12 12.2 0.1 2.8 2 1 1 3 3 3 0 GAGA factor zf-met PF12874.7 KFP07639.1 - 0.24 11.9 0.2 0.24 11.9 0.2 5.9 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KFP07639.1 - 0.44 11.0 22.0 0.78 10.2 1.2 5.5 5 1 1 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger DUF4764 PF15961.5 KFP07639.1 - 6 5.4 7.0 12 4.5 7.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4764) Peptidase_M24 PF00557.24 KFP07640.1 - 2.2e-21 76.5 0.2 2.6e-21 76.3 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 adh_short PF00106.25 KFP07641.1 - 3.1e-48 163.8 0.4 3.5e-48 163.7 0.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP07641.1 - 4.9e-32 111.4 0.4 6.4e-32 111.0 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP07641.1 - 1.2e-10 41.6 0.3 1.7e-10 41.1 0.3 1.1 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 KFP07641.1 - 0.13 13.0 0.2 0.32 11.7 0.2 1.8 1 1 0 1 1 1 0 Methyltransferase domain Rad52_Rad22 PF04098.15 KFP07642.1 - 7.5e-08 32.4 0.1 9.9e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein RRM_1 PF00076.22 KFP07642.1 - 8.1e-05 22.4 0.0 0.00019 21.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RPW8 PF05659.11 KFP07642.1 - 0.045 13.4 0.2 0.073 12.8 0.2 1.3 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Hormone_1 PF00103.20 KFP07643.1 - 6.2e-15 55.5 0.0 6.7e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 Somatotropin hormone family Ion_trans PF00520.31 KFP07644.1 - 1.1e-143 476.7 73.9 2.3e-63 213.7 24.1 3.1 3 0 0 3 3 3 3 Ion transport protein Na_trans_assoc PF06512.13 KFP07644.1 - 6.8e-50 170.2 5.5 1.4e-48 165.9 5.5 2.3 1 1 0 1 1 1 1 Sodium ion transport-associated PKD_channel PF08016.12 KFP07644.1 - 1.7e-08 33.6 62.8 8e-05 21.5 1.3 6.7 4 3 2 6 6 6 5 Polycystin cation channel IQ PF00612.27 KFP07644.1 - 0.00015 21.2 1.2 0.00043 19.8 1.2 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif GPHH PF16905.5 KFP07644.1 - 0.00025 20.7 0.0 0.00047 19.9 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Collagen PF01391.18 KFP07645.1 - 6e-59 195.7 273.2 8.5e-08 31.8 22.7 10.6 2 1 5 7 7 7 6 Collagen triple helix repeat (20 copies) C1q PF00386.21 KFP07645.1 - 6.6e-36 123.3 0.1 8e-36 123.1 0.1 1.1 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 KFP07645.1 - 0.029 14.3 0.0 0.042 13.7 0.0 1.1 1 0 0 1 1 1 0 BclA C-terminal domain Glyco_transf_29 PF00777.18 KFP07646.1 - 6e-66 222.6 0.0 7.5e-66 222.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Coprogen_oxidas PF01218.18 KFP07647.1 - 2.2e-129 430.4 0.0 2.5e-129 430.2 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase SNF2_N PF00176.23 KFP07648.1 - 2.7e-75 253.3 2.8 2e-74 250.4 0.1 2.3 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KFP07648.1 - 5.5e-15 55.7 0.0 2.7e-14 53.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP07648.1 - 6.3e-08 32.8 0.7 2.5e-07 30.9 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit 7tm_1 PF00001.21 KFP07649.1 - 3.7e-48 164.1 19.1 3.7e-48 164.1 19.1 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP07649.1 - 0.00091 18.9 19.4 0.00091 18.9 19.4 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.15 KFP07649.1 - 2.3 8.2 12.4 0.23 11.4 2.3 2.3 2 0 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa TIP41 PF04176.13 KFP07650.1 - 5.4e-67 224.6 0.6 6.5e-67 224.3 0.6 1.1 1 0 0 1 1 1 1 TIP41-like family DGF-1_4 PF11024.8 KFP07650.1 - 0.26 12.1 1.7 0.45 11.3 0.5 1.9 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 Got1 PF04178.12 KFP07651.1 - 2e-38 131.3 18.2 3.2e-36 124.2 10.1 2.0 1 1 1 2 2 2 2 Got1/Sft2-like family DUF2244 PF10003.9 KFP07651.1 - 1.1 8.9 12.0 0.083 12.6 3.9 2.1 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF4064 PF13273.6 KFP07651.1 - 1.2 9.4 8.3 6.6 7.1 8.0 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) T-box PF00907.22 KFP07652.1 - 2e-69 233.5 0.0 2.6e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 T-box IL8 PF00048.20 KFP07653.1 - 2.1e-10 40.6 0.3 3.5e-10 39.9 0.3 1.3 1 1 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like DERM PF14704.6 KFP07654.1 - 1.1e-25 90.9 3.8 1.3e-25 90.7 3.8 1.1 1 0 0 1 1 1 1 Dermatopontin NDK PF00334.19 KFP07655.1 - 1.1e-72 242.4 0.0 2.5e-40 137.6 0.0 2.1 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 KFP07655.1 - 5.7e-06 26.1 0.7 2.8e-05 23.9 0.3 2.1 2 0 0 2 2 2 1 DUF1126 PH-like domain Arg_repressor PF01316.21 KFP07655.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain DUF2249 PF10006.9 KFP07655.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) DASH_Hsk3 PF08227.11 KFP07656.1 - 1.1e-09 38.5 0.6 2.9e-09 37.1 0.1 2.0 2 0 0 2 2 2 1 DASH complex subunit Hsk3 like Mig-14 PF07395.11 KFP07656.1 - 0.038 13.4 0.5 0.069 12.5 0.5 1.4 1 0 0 1 1 1 0 Mig-14 MbeD_MobD PF04899.12 KFP07656.1 - 0.12 12.5 0.5 0.12 12.5 0.5 3.3 1 1 2 3 3 3 0 MbeD/MobD like PI3K_P85_iSH2 PF16454.5 KFP07656.1 - 0.88 9.2 15.0 0.15 11.6 5.0 2.5 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain CC2-LZ PF16516.5 KFP07656.1 - 1 9.8 11.4 78 3.7 11.4 3.3 1 1 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator KASH_CCD PF14662.6 KFP07656.1 - 1.3 8.9 19.9 3 7.6 19.9 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Folate_carrier PF01770.18 KFP07658.1 - 2.9e-169 563.2 25.2 3.5e-169 562.9 25.2 1.1 1 0 0 1 1 1 1 Reduced folate carrier MFS_1 PF07690.16 KFP07658.1 - 3.3e-09 36.2 20.9 3.3e-09 36.2 20.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily F5_F8_type_C PF00754.25 KFP07659.1 - 1.1e-51 174.2 8.1 2e-26 92.6 0.6 3.1 3 0 0 3 3 3 2 F5/8 type C domain Cu-oxidase_3 PF07732.15 KFP07659.1 - 5.7e-31 107.0 0.2 9.2e-09 35.3 0.0 5.4 5 1 0 5 5 5 4 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFP07659.1 - 4e-16 59.0 3.8 9.3e-07 28.7 0.5 5.6 5 0 0 5 5 5 3 Multicopper oxidase DUF4232 PF14016.6 KFP07659.1 - 0.075 13.2 0.0 0.6 10.2 0.0 2.5 4 0 0 4 4 4 0 Protein of unknown function (DUF4232) Autophagy_N PF03986.13 KFP07660.1 - 4.8e-52 175.5 1.4 5.9e-52 175.2 0.5 1.6 1 1 1 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 KFP07660.1 - 1.5e-20 73.6 4.1 3.4e-20 72.4 4.1 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 KFP07660.1 - 5.7e-16 57.7 0.7 1.1e-15 56.9 0.7 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal SDA1 PF05285.12 KFP07660.1 - 0.15 11.4 4.9 0.23 10.8 4.7 1.4 2 0 0 2 2 2 0 SDA1 Nuc_sug_transp PF04142.15 KFP07661.1 - 2.3e-50 171.6 11.0 3e-50 171.2 11.0 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KFP07661.1 - 2.3e-06 27.8 5.5 2.3e-06 27.8 5.5 3.3 3 1 0 3 3 3 1 EamA-like transporter family HCMV_UL124 PF17609.2 KFP07661.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function DUF4174 PF13778.6 KFP07662.1 - 9.1e-107 352.1 0.1 8.7e-38 129.5 1.5 3.6 3 0 0 3 3 3 3 Domain of unknown function (DUF4174) V-set PF07686.17 KFP07663.1 - 1.4e-08 34.9 0.1 4.7e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP07663.1 - 2.9e-06 27.8 1.0 0.0053 17.3 0.2 2.4 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFP07663.1 - 1.8e-05 24.7 0.3 4.9e-05 23.3 0.2 1.7 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain I-set PF07679.16 KFP07663.1 - 0.00017 21.6 0.0 0.034 14.2 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFP07663.1 - 0.00031 20.9 2.1 0.63 10.3 0.1 2.9 2 1 0 2 2 2 2 Immunoglobulin domain MMR_HSR1 PF01926.23 KFP07664.1 - 1.3e-20 73.6 0.0 1.6e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP07664.1 - 5.3e-08 32.6 0.0 3.1e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KFP07664.1 - 2.1e-06 27.4 0.0 3.3e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFP07664.1 - 5.8e-06 26.3 0.0 0.00051 20.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 KFP07664.1 - 5.4e-05 22.7 0.0 6.8e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 KFP07664.1 - 0.00015 21.9 0.1 0.061 13.4 0.0 2.1 1 1 1 2 2 2 2 Dynamin family IIGP PF05049.13 KFP07664.1 - 0.0049 16.0 0.0 0.0071 15.4 0.0 1.3 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 KFP07664.1 - 0.017 15.4 0.0 0.026 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KFP07664.1 - 0.023 14.5 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Gtr1_RagA PF04670.12 KFP07664.1 - 0.04 13.3 0.0 0.045 13.1 0.0 1.2 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Roc PF08477.13 KFP07664.1 - 0.041 14.1 0.0 0.068 13.4 0.0 1.7 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 KFP07664.1 - 0.058 13.1 0.0 0.064 13.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 KFP07664.1 - 0.14 11.9 0.0 1.5 8.6 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 KFP07664.1 - 0.18 11.5 0.0 1.2 8.9 0.0 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TFIID-18kDa PF02269.16 KFP07665.1 - 1.9e-38 130.3 0.4 2.2e-38 130.1 0.4 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit GTP_EFTU_D2 PF03144.25 KFP07665.1 - 0.12 12.8 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu domain 2 DUF4477 PF14780.6 KFP07666.1 - 4.8e-48 163.3 4.0 6.5e-48 162.9 4.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) KIND PF16474.5 KFP07667.1 - 1.1e-40 139.7 0.4 1e-30 107.1 0.0 2.1 1 1 1 2 2 2 2 Kinase non-catalytic C-lobe domain Ig_3 PF13927.6 KFP07668.1 - 4.1e-50 168.3 0.4 2.1e-14 53.9 0.0 5.6 5 0 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 KFP07668.1 - 1e-47 160.1 0.0 3.2e-17 62.4 0.0 5.1 6 0 0 6 6 5 4 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP07668.1 - 3.8e-36 123.3 0.0 3.6e-11 43.3 0.0 4.5 4 0 0 4 4 4 4 Immunoglobulin domain fn3 PF00041.21 KFP07668.1 - 5.8e-36 122.7 2.0 3.6e-13 49.7 0.0 3.5 3 0 0 3 3 3 3 Fibronectin type III domain ig PF00047.25 KFP07668.1 - 2.7e-28 97.9 0.0 6.8e-09 35.8 0.0 4.7 4 0 0 4 4 4 3 Immunoglobulin domain ISET-FN3_linker PF16625.5 KFP07668.1 - 8.9e-23 80.6 9.2 1.3e-22 80.1 6.7 2.8 2 0 0 2 2 1 1 Unstructured linking region I-set and fnIII on Brother of CDO V-set PF07686.17 KFP07668.1 - 5.1e-13 49.2 4.3 0.012 15.7 0.1 7.9 5 3 1 6 6 6 3 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 KFP07668.1 - 9e-11 42.2 0.3 0.0046 17.5 0.0 4.1 4 0 0 4 4 3 2 Purple acid Phosphatase, N-terminal domain C2-set_2 PF08205.12 KFP07668.1 - 1.7e-09 37.6 0.3 0.014 15.4 0.0 4.6 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFP07668.1 - 5.9e-09 36.1 0.0 0.028 14.7 0.0 4.3 4 0 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFP07668.1 - 8.4e-08 31.7 0.0 0.028 14.0 0.0 4.2 4 0 0 4 4 4 2 Immunoglobulin domain Ig_5 PF16681.5 KFP07668.1 - 8.9e-08 32.4 0.0 0.065 13.6 0.0 4.5 4 0 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFP07668.1 - 0.00096 19.2 0.0 21 5.3 0.0 3.9 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain C1-set PF07654.15 KFP07668.1 - 0.0022 18.3 0.2 1.1 9.7 0.0 4.4 4 1 0 4 4 3 1 Immunoglobulin C1-set domain Ig_C17orf99 PF17736.1 KFP07668.1 - 0.0058 16.6 0.2 8.7 6.5 0.0 4.2 4 1 0 4 4 3 1 C17orf99 Ig domain C2-set PF05790.15 KFP07668.1 - 0.028 14.6 0.0 24 5.2 0.0 3.6 3 0 0 3 3 3 0 Immunoglobulin C2-set domain Interfer-bind PF09294.10 KFP07668.1 - 0.049 14.0 0.2 2.3 8.6 0.0 3.1 4 0 0 4 4 3 0 Interferon-alpha/beta receptor, fibronectin type III Y_Y_Y PF07495.13 KFP07668.1 - 0.066 13.2 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 Y_Y_Y domain Na_Ca_ex PF01699.24 KFP07668.1 - 0.15 12.1 0.3 0.26 11.2 0.3 1.3 1 0 0 1 1 1 0 Sodium/calcium exchanger protein TNFR_16_TM PF18422.1 KFP07668.1 - 0.27 11.2 3.2 0.42 10.6 1.2 2.1 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain Leu_zip PF15294.6 KFP07670.1 - 0.56 9.7 35.9 0.034 13.7 17.0 2.5 2 1 0 2 2 2 0 Leucine zipper GAS PF13851.6 KFP07670.1 - 2 7.7 42.5 1.9 7.8 7.8 4.1 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding LSR PF05624.14 KFP07671.1 - 1.7e-21 75.9 36.1 2.7e-21 75.3 36.1 1.3 1 0 0 1 1 1 1 Lipolysis stimulated receptor (LSR) V-set PF07686.17 KFP07671.1 - 2.5e-05 24.4 6.4 0.0011 19.1 0.0 3.3 3 1 1 4 4 4 2 Immunoglobulin V-set domain ig PF00047.25 KFP07671.1 - 0.025 14.8 0.1 1.9 8.8 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain Apo-VLDL-II PF05418.11 KFP07672.1 - 2.4e-44 149.8 0.3 2.9e-44 149.5 0.3 1.1 1 0 0 1 1 1 1 Apovitellenin I (Apo-VLDL-II) VPS13_C PF16909.5 KFP07673.1 - 3.3e-28 98.6 0.3 2.1e-26 92.8 0.0 2.6 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 KFP07673.1 - 2.4e-10 40.3 7.3 1.1e-06 28.3 0.0 4.6 4 1 2 6 6 6 4 SHR-binding domain of vacuolar-sorting associated protein 13 ATG_C PF09333.11 KFP07673.1 - 1.2e-05 25.6 0.0 4.3e-05 23.8 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain COX6C PF02937.15 KFP07674.1 - 8.5e-31 105.9 3.0 9.3e-31 105.8 3.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIc RGS PF00615.19 KFP07675.1 - 9.9e-09 35.5 0.1 1.3e-08 35.1 0.1 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain HHH_3 PF12836.7 KFP07675.1 - 0.0024 18.1 0.0 0.0099 16.1 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif tify PF06200.14 KFP07675.1 - 0.24 10.7 0.8 15 5.0 0.1 2.3 2 0 0 2 2 2 0 tify domain IBR PF01485.21 KFP07676.1 - 1e-05 25.7 4.9 1e-05 25.7 4.9 2.0 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain Phage_holin_8 PF16931.5 KFP07676.1 - 0.23 11.4 0.0 0.4 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative phage holin DNA_RNApol_7kD PF03604.13 KFP07677.1 - 1.7e-17 62.8 8.8 2.6e-17 62.2 8.8 1.3 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit A2L_zn_ribbon PF08792.10 KFP07677.1 - 0.0005 19.7 1.0 0.00092 18.9 1.0 1.4 1 0 0 1 1 1 1 A2L zinc ribbon domain Cytochrome_C7 PF14522.6 KFP07677.1 - 0.0042 17.0 0.4 0.0053 16.7 0.4 1.2 1 0 0 1 1 1 1 Cytochrome c7 and related cytochrome c DZR PF12773.7 KFP07677.1 - 0.0054 16.7 1.8 0.0069 16.4 1.8 1.3 1 0 0 1 1 1 1 Double zinc ribbon MCM_OB PF17207.3 KFP07677.1 - 0.0069 16.2 1.8 0.0071 16.2 1.8 1.0 1 0 0 1 1 1 1 MCM OB domain HypA PF01155.19 KFP07677.1 - 0.014 15.4 1.7 0.017 15.2 1.7 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_13 PF09855.9 KFP07677.1 - 0.11 12.7 0.6 0.11 12.7 0.6 1.7 1 1 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) TPR_1 PF00515.28 KFP07678.1 - 1.9e-48 160.3 19.1 2.2e-06 27.2 0.4 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 KFP07678.1 - 9.7e-35 115.9 12.5 0.00027 20.8 0.1 9.6 8 1 1 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.6 KFP07678.1 - 1.1e-16 59.5 16.0 0.031 14.5 0.2 9.0 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_9 PF13371.6 KFP07678.1 - 9.6e-16 57.7 1.3 2.4e-06 27.6 0.0 5.0 3 1 1 4 4 4 2 Tetratricopeptide repeat RPAP3_C PF13877.6 KFP07678.1 - 3e-15 56.5 0.1 1.1e-14 54.7 0.0 2.1 2 0 0 2 2 1 1 Potential Monad-binding region of RPAP3 TPR_11 PF13414.6 KFP07678.1 - 5.6e-14 51.5 12.7 2.3e-05 24.0 0.0 7.5 6 1 2 8 8 8 2 TPR repeat TPR_12 PF13424.6 KFP07678.1 - 8e-14 51.7 18.7 0.00057 20.1 1.0 8.1 4 3 3 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFP07678.1 - 6.3e-11 42.6 10.5 0.046 14.2 0.0 6.0 5 1 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFP07678.1 - 4.5e-10 40.0 2.7 0.015 16.0 0.0 6.2 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFP07678.1 - 7.3e-09 35.0 11.1 0.5 10.5 0.0 7.2 9 0 0 9 9 6 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFP07678.1 - 1.4e-08 34.7 11.8 0.052 13.6 0.0 6.3 5 2 1 6 6 6 3 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 KFP07678.1 - 1.4e-05 25.5 4.7 2.1 9.4 0.0 7.0 5 2 4 9 9 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFP07678.1 - 4.9e-05 23.0 3.3 0.027 14.3 0.2 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFP07678.1 - 5.2e-05 23.3 15.4 0.049 14.0 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFP07678.1 - 0.0002 21.8 8.5 12 6.8 0.0 7.4 7 0 0 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP07678.1 - 0.00039 20.6 13.6 0.2 11.9 2.3 4.0 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 KFP07678.1 - 0.0017 18.4 15.5 3.5 7.8 0.1 6.3 5 1 1 6 6 6 1 MIT (microtubule interacting and transport) domain DUF4919 PF16266.5 KFP07678.1 - 0.0028 17.6 3.0 0.13 12.2 0.0 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF4919) TPR_20 PF14561.6 KFP07678.1 - 0.0039 17.5 0.6 0.057 13.8 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFP07678.1 - 0.017 14.4 0.6 2.9 7.0 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KFP07678.1 - 0.02 14.4 3.7 45 3.6 0.0 5.8 7 0 0 7 7 7 0 SHNi-TPR XOO_2897-deam PF14440.6 KFP07678.1 - 0.047 13.8 1.8 0.097 12.8 0.1 2.4 2 0 0 2 2 2 0 Xanthomonas XOO_2897-like deaminase DUF5344 PF17279.2 KFP07678.1 - 8 7.1 8.7 2.8 8.6 0.3 4.2 4 0 0 4 4 3 0 Family of unknown function (DUF5344) IBR PF01485.21 KFP07679.1 - 9.5e-19 67.4 28.5 1.9e-13 50.4 11.5 5.2 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KFP07679.1 - 0.0027 18.0 9.8 0.0027 18.0 9.8 4.6 4 1 1 5 5 5 1 Ring finger domain zf-C3HC4 PF00097.25 KFP07679.1 - 0.0029 17.4 9.3 0.0029 17.4 9.3 4.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP07679.1 - 0.0053 16.7 8.1 0.0053 16.7 8.1 4.1 4 1 0 4 4 4 1 zinc-RING finger domain RVT_1 PF00078.27 KFP07680.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ank_4 PF13637.6 KFP07681.1 - 6.7e-22 77.6 0.6 1.1e-10 41.8 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP07681.1 - 1e-15 58.1 0.1 4.6e-13 49.6 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP07681.1 - 1.3e-12 47.7 0.1 1e-10 41.6 0.2 3.0 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KFP07681.1 - 1.7e-11 44.0 4.3 0.00015 22.1 0.2 4.3 3 1 1 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KFP07681.1 - 3.1e-10 39.4 2.3 0.00069 19.9 0.1 4.6 5 0 0 5 5 5 3 Ankyrin repeat RRM_1 PF00076.22 KFP07682.1 - 5.9e-70 231.0 4.2 4.9e-25 87.1 0.2 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KFP07682.1 - 1.2e-32 111.9 0.2 5.7e-32 109.7 0.2 2.1 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 KFP07682.1 - 1.1e-07 31.4 0.2 0.094 12.3 0.1 3.6 1 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KFP07682.1 - 2.5e-05 24.3 0.6 1.9 8.6 0.0 3.6 3 0 0 3 3 3 2 Limkain b1 SET_assoc PF11767.8 KFP07682.1 - 4.9e-05 22.9 0.3 4.4 7.0 0.1 3.6 3 0 0 3 3 3 2 Histone lysine methyltransferase SET associated RRM_occluded PF16842.5 KFP07682.1 - 0.00019 21.3 0.0 0.29 11.0 0.0 3.4 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KFP07682.1 - 0.0003 20.8 8.7 0.13 12.3 1.0 3.5 4 0 0 4 4 3 2 RNA binding motif Nup35_RRM_2 PF14605.6 KFP07682.1 - 0.0016 18.4 0.2 6.9 6.8 0.0 3.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif ATP-grasp_2 PF08442.10 KFP07682.1 - 0.0018 17.9 0.3 1.4 8.4 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain HATPase_c PF02518.26 KFP07682.1 - 0.0025 18.3 0.2 1.7 9.2 0.1 2.3 1 1 1 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RRM_7 PF16367.5 KFP07682.1 - 0.0025 17.9 0.7 7.8 6.7 0.0 4.2 2 2 1 3 3 3 1 RNA recognition motif OB_RNB PF08206.11 KFP07682.1 - 0.014 15.1 3.0 4 7.2 0.1 3.4 3 0 0 3 3 3 0 Ribonuclease B OB domain YflT PF11181.8 KFP07682.1 - 0.035 14.6 1.3 1.7 9.2 0.2 2.8 3 0 0 3 3 3 0 Heat induced stress protein YflT 14-3-3 PF00244.20 KFP07683.1 - 3.1e-107 357.1 8.4 3.4e-107 357.0 8.4 1.0 1 0 0 1 1 1 1 14-3-3 protein FliM PF02154.15 KFP07683.1 - 0.019 14.9 0.1 0.031 14.2 0.1 1.4 1 0 0 1 1 1 0 Flagellar motor switch protein FliM CSN7a_helixI PF18392.1 KFP07683.1 - 0.072 13.0 1.7 0.19 11.7 0.7 2.1 1 1 1 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain Peptidase_C98 PF15499.6 KFP07683.1 - 0.076 12.5 0.4 0.14 11.6 0.4 1.5 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF4518 PF15008.6 KFP07683.1 - 0.38 9.9 3.5 5.8 6.0 3.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) 4F5 PF04419.14 KFP07684.1 - 7.1e-11 42.8 17.3 9.3e-11 42.4 17.3 1.2 1 0 0 1 1 1 1 4F5 protein family zf-met PF12874.7 KFP07684.1 - 1.9e-05 24.9 0.2 3e-05 24.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP07684.1 - 0.0027 18.0 0.3 0.0045 17.2 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_12 PF18658.1 KFP07684.1 - 0.0069 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KFP07684.1 - 0.011 16.5 1.3 0.016 16.0 1.3 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger Ribosomal_L44 PF00935.19 KFP07684.1 - 0.013 15.9 4.0 0.016 15.7 4.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L44 DUF629 PF04780.12 KFP07684.1 - 0.02 13.4 1.4 0.021 13.4 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-met2 PF12907.7 KFP07684.1 - 0.052 13.7 4.8 0.37 11.0 4.8 2.2 1 1 0 1 1 1 0 Zinc-binding PLATZ PF04640.14 KFP07684.1 - 0.054 14.1 1.7 0.072 13.7 1.7 1.2 1 0 0 1 1 1 0 PLATZ transcription factor CP2 PF04516.15 KFP07685.1 - 3.2e-86 288.4 4.2 5.5e-86 287.6 4.2 1.3 1 0 0 1 1 1 1 CP2 transcription factor EF-hand_7 PF13499.6 KFP07686.1 - 3e-23 82.0 0.7 6.1e-12 45.8 0.0 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KFP07686.1 - 3.5e-20 70.0 4.8 2e-07 30.1 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFP07686.1 - 1.6e-18 65.0 1.4 1.6e-06 27.6 0.1 4.6 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KFP07686.1 - 2.6e-18 64.6 4.5 4.7e-06 25.9 0.1 4.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 KFP07686.1 - 1e-12 47.7 5.2 8.1e-07 28.8 0.2 4.1 3 2 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFP07686.1 - 5.7e-05 23.4 0.1 0.086 13.2 0.0 2.6 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFP07686.1 - 0.00076 19.4 0.2 0.14 12.1 0.0 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KFP07686.1 - 0.036 14.3 0.1 8.5 6.7 0.0 2.4 2 1 0 2 2 2 0 Dockerin type I domain Fe_hyd_SSU PF02256.17 KFP07686.1 - 0.081 13.0 0.2 7 6.8 0.0 2.9 2 1 1 3 3 3 0 Iron hydrogenase small subunit Ribonuc_red_sm PF00268.21 KFP07687.1 - 2.3e-123 411.1 0.6 2.8e-123 410.8 0.6 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain HECT PF00632.25 KFP07688.1 - 6.7e-63 213.0 0.0 1.1e-62 212.3 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) E3_UbLigase_EDD PF11547.8 KFP07688.1 - 1.2e-30 105.0 3.9 3.4e-30 103.5 3.9 1.9 1 0 0 1 1 1 1 E3 ubiquitin ligase EDD PABP PF00658.18 KFP07688.1 - 6.5e-20 71.1 0.0 1.4e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain HSP20 PF00011.21 KFP07689.1 - 9.2e-11 41.8 0.1 1e-10 41.6 0.1 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KFP07689.1 - 0.068 12.7 0.1 0.1 12.2 0.1 1.3 1 1 0 1 1 1 0 HSP20-like domain found in ArsA zf-C2H2 PF00096.26 KFP07690.1 - 2.8e-12 46.4 23.8 0.00044 20.6 3.0 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP07690.1 - 1.3e-09 38.1 10.0 2.8e-06 27.5 1.9 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP07690.1 - 9.5e-09 35.4 19.9 0.0034 18.1 1.8 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFP07690.1 - 0.00056 20.5 6.6 1.9 9.2 0.3 3.5 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KFP07690.1 - 0.014 15.7 7.1 0.048 14.0 7.1 1.9 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-Di19 PF05605.12 KFP07690.1 - 0.038 14.3 6.0 0.16 12.3 1.2 2.7 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf_Hakai PF18408.1 KFP07690.1 - 0.051 13.3 0.4 0.051 13.3 0.4 2.6 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain zf-TRAF PF02176.18 KFP07690.1 - 0.36 11.6 3.9 0.22 12.2 0.9 2.3 1 1 0 1 1 1 0 TRAF-type zinc finger zf-C2HC_2 PF13913.6 KFP07690.1 - 4 7.4 7.7 5.7 7.0 0.3 3.3 2 1 1 3 3 3 0 zinc-finger of a C2HC-type Orn_Arg_deC_N PF02784.16 KFP07691.1 - 9.2e-77 257.7 0.0 1.2e-76 257.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KFP07691.1 - 8.5e-20 70.8 0.0 1.1e-19 70.5 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain V-ATPase_C PF03223.15 KFP07692.1 - 4.4e-145 483.7 11.9 2.3e-144 481.4 11.9 1.8 1 1 0 1 1 1 1 V-ATPase subunit C Folliculin PF11704.8 KFP07692.1 - 0.03 14.2 0.7 0.087 12.7 0.0 2.0 2 1 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Frizzled PF01534.17 KFP07694.1 - 4.6e-118 394.0 17.5 7.1e-118 393.3 17.5 1.3 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 KFP07694.1 - 3.1e-27 95.4 6.2 8e-27 94.1 6.2 1.8 1 0 0 1 1 1 1 Fz domain Folate_rec PF03024.14 KFP07694.1 - 0.0033 17.3 2.4 0.0089 15.9 2.4 1.7 1 0 0 1 1 1 1 Folate receptor family LapA_dom PF06305.11 KFP07694.1 - 0.18 11.6 0.7 0.86 9.5 0.1 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain RseC_MucC PF04246.12 KFP07694.1 - 0.34 10.8 4.3 0.37 10.7 0.1 2.8 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Collagen PF01391.18 KFP07695.1 - 3.5e-07 29.9 6.7 5.9e-07 29.1 6.7 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Mito_carr PF00153.27 KFP07696.1 - 2.6e-63 210.0 2.8 4.4e-23 81.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sof1 PF04158.14 KFP07697.1 - 2.9e-35 120.4 9.4 4.7e-35 119.7 9.4 1.3 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KFP07697.1 - 1.4e-21 76.3 13.6 0.00035 21.3 0.1 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.11 KFP07697.1 - 5.1e-07 29.8 1.0 0.00047 20.1 0.1 3.6 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KFP07697.1 - 8.2e-06 26.0 0.0 0.027 14.7 0.0 3.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP07697.1 - 0.026 13.5 0.2 2.5 7.0 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DC_STAMP PF07782.13 KFP07698.1 - 8.9e-57 192.0 4.9 8.9e-57 192.0 4.9 1.7 2 0 0 2 2 2 1 DC-STAMP-like protein Holin_SPP1 PF04688.13 KFP07698.1 - 0.094 12.9 0.7 0.46 10.7 0.1 2.3 2 0 0 2 2 2 0 SPP1 phage holin Amidohydro_1 PF01979.20 KFP07699.1 - 1.4e-35 123.3 0.3 2.4e-35 122.5 0.3 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFP07699.1 - 4.6e-15 56.1 0.4 3.1e-08 33.5 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_2 PF04909.14 KFP07699.1 - 0.0026 17.6 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase AP_endonuc_2 PF01261.24 KFP07699.1 - 0.071 12.5 0.0 0.12 11.8 0.0 1.5 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel CUB PF00431.20 KFP07700.1 - 1.4e-47 160.5 1.6 1.4e-25 89.7 0.0 2.8 3 0 0 3 3 3 2 CUB domain Ldl_recept_a PF00057.18 KFP07700.1 - 4.7e-37 125.9 82.1 3.1e-11 43.3 14.9 5.7 5 0 0 5 5 5 5 Low-density lipoprotein receptor domain class A zf-C2H2 PF00096.26 KFP07701.1 - 4.4e-10 39.5 50.6 0.011 16.1 0.3 8.7 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFP07701.1 - 6.7e-09 35.8 52.5 0.05 13.9 0.7 8.5 8 0 0 8 8 8 7 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KFP07701.1 - 4.8e-08 33.2 48.8 0.23 12.4 0.1 8.9 8 0 0 8 8 8 5 C2H2-type zinc finger zf-met PF12874.7 KFP07701.1 - 1.4e-07 31.6 51.0 0.0096 16.3 0.7 8.6 8 0 0 8 8 8 6 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFP07701.1 - 0.072 13.4 21.8 0.023 15.0 4.9 5.7 6 0 0 6 6 6 0 C2H2-type zinc ribbon GATA PF00320.27 KFP07701.1 - 0.45 10.2 4.2 14 5.4 0.0 3.6 3 0 0 3 3 3 0 GATA zinc finger zf-C2H2_3 PF13878.6 KFP07701.1 - 3.8 7.4 12.9 13 5.7 0.1 5.9 6 0 0 6 6 6 0 zinc-finger of acetyl-transferase ESCO TLD PF07534.16 KFP07703.1 - 4.8e-40 137.0 0.1 5.4e-40 136.8 0.1 1.0 1 0 0 1 1 1 1 TLD Costars PF14705.6 KFP07704.1 - 2.2e-33 114.2 0.0 3.9e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 Costars Fibrinogen_C PF00147.18 KFP07705.1 - 2.5e-69 233.5 5.6 3.4e-69 233.0 5.6 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain HlyD_2 PF12700.7 KFP07705.1 - 3 6.5 15.3 6.2 5.4 15.3 1.4 1 0 0 1 1 1 0 HlyD family secretion protein FapA PF03961.13 KFP07705.1 - 4 5.9 13.4 5.8 5.4 13.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Furin-like_2 PF15913.5 KFP07707.1 - 1.2e-40 138.0 22.1 1.2e-40 138.0 22.1 1.8 2 0 0 2 2 2 1 Furin-like repeat, cysteine-rich VSP PF03302.13 KFP07707.1 - 0.0045 15.9 11.8 0.0045 15.9 11.8 1.7 1 1 1 2 2 2 1 Giardia variant-specific surface protein Toprim PF01751.22 KFP07707.1 - 0.17 12.1 0.0 0.25 11.6 0.0 1.2 1 0 0 1 1 1 0 Toprim domain eIF3_N PF09440.10 KFP07708.1 - 2.4e-47 160.7 4.6 8.3e-47 159.0 4.6 2.0 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KFP07708.1 - 2.6e-19 69.7 0.1 1.1e-18 67.6 0.0 2.2 2 0 0 2 2 2 1 PCI domain HD_assoc PF13286.6 KFP07708.1 - 0.061 13.9 1.4 2.4 8.7 0.2 2.6 2 0 0 2 2 2 0 Phosphohydrolase-associated domain PARP_reg PF02877.14 KFP07708.1 - 0.11 12.6 0.3 2.1 8.5 0.1 2.7 3 0 0 3 3 3 0 Poly(ADP-ribose) polymerase, regulatory domain TPR_19 PF14559.6 KFP07709.1 - 5.8e-11 42.7 7.7 1e-05 26.0 1.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP07709.1 - 2.9e-10 40.1 7.3 0.0062 17.3 0.4 5.2 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFP07709.1 - 3.9e-10 39.1 10.3 0.00047 20.1 0.6 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFP07709.1 - 8.1e-07 28.6 4.7 0.061 13.2 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFP07709.1 - 8.9e-07 29.5 0.8 0.79 10.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP07709.1 - 0.00044 20.3 11.2 0.26 11.6 0.2 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat NARP1 PF12569.8 KFP07709.1 - 0.0051 15.8 4.8 0.0051 15.8 4.8 2.4 1 1 2 3 3 3 1 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 KFP07709.1 - 0.01 15.8 1.7 5 7.4 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KFP07709.1 - 0.014 15.8 8.6 0.38 11.2 0.5 3.1 1 1 2 3 3 3 0 Alkyl sulfatase dimerisation TPR_6 PF13174.6 KFP07709.1 - 0.015 15.9 7.0 5.8 7.8 0.1 4.9 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFP07709.1 - 0.024 14.8 1.5 3.5 7.8 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 KFP07709.1 - 0.026 14.8 1.4 0.5 10.7 0.1 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat MyTH4 PF00784.17 KFP07709.1 - 0.15 12.6 1.8 19 5.8 0.2 3.2 2 1 1 3 3 3 0 MyTH4 domain ANAPC3 PF12895.7 KFP07709.1 - 0.21 11.9 10.3 0.64 10.3 3.8 3.4 1 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Ribonuclease_T2 PF00445.18 KFP07709.1 - 0.24 11.6 4.5 0.57 10.4 4.5 1.7 1 1 0 1 1 1 0 Ribonuclease T2 family TPR_17 PF13431.6 KFP07709.1 - 0.65 10.5 5.8 5.1 7.7 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFP07709.1 - 3.8 7.9 12.8 1.1 9.6 1.3 3.8 3 1 0 4 4 3 0 Tetratricopeptide repeat Neurensin PF14927.6 KFP07710.1 - 9.2e-08 31.9 0.0 1.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Neurensin AKNA PF12443.8 KFP07711.1 - 0.021 15.5 0.2 0.021 15.5 0.2 1.1 1 0 0 1 1 1 0 AT-hook-containing transcription factor 7tm_1 PF00001.21 KFP07712.1 - 9.4e-51 172.7 24.8 1.3e-50 172.2 24.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP07712.1 - 8e-10 38.5 24.8 1.8e-09 37.4 24.8 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP07712.1 - 5.4e-07 29.5 27.0 5.4e-07 29.5 27.0 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP07712.1 - 9.3e-06 25.6 20.6 2.9e-05 24.0 13.2 2.2 2 0 0 2 2 2 2 Olfactory receptor Ribosomal_L18A PF01775.17 KFP07712.1 - 0.047 13.8 0.2 0.53 10.4 0.0 2.3 2 0 0 2 2 2 0 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A RRM_1 PF00076.22 KFP07713.1 - 1.7e-13 50.2 0.0 2.6e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.16 KFP07714.1 - 1.5e-28 99.8 29.9 1.5e-28 99.8 29.9 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP07714.1 - 5.1e-11 42.1 10.2 5.1e-11 42.1 10.2 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KFP07714.1 - 2.1e-09 36.2 20.1 5.5e-07 28.3 0.9 4.1 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family Tetraspanin PF00335.20 KFP07714.1 - 5.2 6.7 12.2 0.88 9.2 6.3 2.5 2 1 0 2 2 2 0 Tetraspanin family MFS_1 PF07690.16 KFP07715.1 - 1.7e-35 122.6 29.1 1.7e-35 122.6 29.1 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP07715.1 - 1.7e-14 53.6 23.1 3.2e-14 52.7 23.1 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 KFP07715.1 - 3.8e-14 51.9 18.3 1.9e-06 26.5 8.6 4.3 1 1 2 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 KFP07715.1 - 0.00059 18.5 9.4 0.00059 18.5 9.4 2.6 2 2 0 2 2 2 2 MFS/sugar transport protein TMEM132D_N PF15705.5 KFP07716.1 - 5.4e-56 188.0 0.0 8.6e-56 187.4 0.0 1.3 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term TMEM132 PF16070.5 KFP07716.1 - 6.6e-17 61.9 3.3 9.8e-17 61.3 3.3 1.3 1 0 0 1 1 1 1 Transmembrane protein family 132 TMEM132 PF16070.5 KFP07717.1 - 2.5e-125 418.4 2.8 3e-125 418.1 2.8 1.1 1 0 0 1 1 1 1 Transmembrane protein family 132 TMEM132D_C PF15706.5 KFP07717.1 - 9.8e-34 115.0 0.3 2.2e-33 113.9 0.0 1.8 2 0 0 2 2 2 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TMEM132D_N PF15705.5 KFP07718.1 - 7.4e-59 197.3 0.2 8.5e-59 197.1 0.2 1.0 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term TMEM132 PF16070.5 KFP07719.1 - 1.6e-69 234.9 4.0 2.2e-41 142.4 0.5 2.4 2 0 0 2 2 2 2 Transmembrane protein family 132 TMEM132D_C PF15706.5 KFP07719.1 - 7.4e-38 128.2 0.0 1.5e-37 127.3 0.0 1.5 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Glycos_transf_1 PF00534.20 KFP07720.1 - 2.9e-21 75.8 0.0 4.2e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFP07720.1 - 1.2e-15 58.1 0.0 2.6e-15 57.1 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KFP07720.1 - 3.3e-08 33.8 0.0 9.2e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 TMEM132 PF16070.5 KFP07721.1 - 4.4e-110 368.3 7.7 6.5e-92 308.5 0.4 2.2 2 0 0 2 2 2 2 Transmembrane protein family 132 TMEM132D_C PF15706.5 KFP07721.1 - 4e-36 122.7 0.0 9.1e-36 121.5 0.0 1.7 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TMEM132D_N PF15705.5 KFP07722.1 - 7.4e-59 197.3 0.2 8.5e-59 197.1 0.2 1.0 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term MIF PF01187.18 KFP07723.1 - 2.6e-37 127.6 0.0 2.8e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Sugar_tr PF00083.24 KFP07724.1 - 6.1e-24 84.7 5.9 6.9e-24 84.5 5.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP07724.1 - 0.00012 21.2 11.8 0.0023 16.9 9.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Dimer_Tnp_hAT PF05699.14 KFP07724.1 - 0.0067 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Phage_holin_1 PF04531.13 KFP07724.1 - 1.3 9.6 4.3 12 6.5 0.2 2.4 2 0 0 2 2 2 0 Bacteriophage holin DUF3792 PF12670.7 KFP07724.1 - 1.7 8.8 12.5 3.3 7.9 12.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) Sugar_tr PF00083.24 KFP07725.1 - 2.9e-47 161.6 4.1 3.4e-47 161.3 4.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP07725.1 - 7.5e-19 67.9 7.2 9e-19 67.6 7.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DER1 PF04511.15 KFP07726.1 - 8.2e-58 195.5 11.9 9.4e-58 195.3 11.9 1.0 1 0 0 1 1 1 1 Der1-like family SNF5 PF04855.12 KFP07727.1 - 9.9e-57 192.5 0.7 8.9e-30 104.2 0.0 2.2 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 DUF1679 PF07914.11 KFP07727.1 - 0.0043 16.0 0.0 0.0061 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) CHCH PF06747.13 KFP07728.1 - 7.5e-06 25.9 5.3 9.9e-06 25.6 5.3 1.2 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.9 KFP07728.1 - 6.5e-05 23.1 1.4 8.1e-05 22.8 1.4 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Cmc1 PF08583.10 KFP07728.1 - 0.028 14.4 0.4 0.039 14.0 0.4 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like V-set PF07686.17 KFP07729.1 - 1.3e-16 60.7 0.0 1.6e-16 60.5 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP07729.1 - 1.9e-05 25.2 0.9 4.9e-05 23.9 0.9 1.6 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP07729.1 - 7e-05 22.9 0.0 0.00019 21.5 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP07729.1 - 0.0047 17.0 0.0 0.0097 16.0 0.0 1.4 1 1 0 1 1 1 1 Immunoglobulin I-set domain Metallophos_2 PF12850.7 KFP07730.1 - 3.4e-18 66.4 0.0 4.5e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KFP07730.1 - 0.032 14.7 0.2 0.11 13.0 0.2 2.0 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase V-set PF07686.17 KFP07731.1 - 3.8e-05 23.8 0.0 4.2e-05 23.7 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP07731.1 - 0.0098 16.5 0.2 0.016 15.8 0.2 1.4 1 1 0 1 1 1 1 Immunoglobulin domain FKBP_C PF00254.28 KFP07731.1 - 0.039 14.3 0.0 0.051 13.9 0.0 1.0 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase V-set PF07686.17 KFP07732.1 - 7.5e-14 51.8 0.1 8.3e-14 51.7 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP07732.1 - 8.3e-08 32.7 0.4 5.4e-07 30.1 0.4 1.9 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP07732.1 - 1.8e-05 25.0 0.2 4.1e-05 23.8 0.2 1.5 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP07732.1 - 3.3e-05 23.9 0.0 0.00064 19.7 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFP07732.1 - 0.00011 22.3 0.2 0.00047 20.3 0.2 1.8 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP07733.1 - 5.1e-12 45.9 0.2 5.6e-12 45.8 0.2 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP07733.1 - 4e-06 27.3 0.8 1.3e-05 25.7 0.8 1.6 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP07733.1 - 0.00082 19.4 0.0 0.0026 17.8 0.0 1.6 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 KFP07733.1 - 0.067 13.4 0.4 0.28 11.4 0.4 1.8 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KFP07734.1 - 1.6e-10 41.1 0.1 1.9e-10 40.9 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP07734.1 - 8.7e-05 23.0 0.3 0.00032 21.2 0.3 1.8 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP07734.1 - 0.0026 17.8 0.0 0.0069 16.4 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain DUF4402 PF14352.6 KFP07734.1 - 0.0096 16.6 1.1 0.013 16.1 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4402) V-set PF07686.17 KFP07735.1 - 3.3e-07 30.4 0.0 3.6e-07 30.3 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP07735.1 - 0.0051 17.4 0.4 0.016 15.8 0.4 1.7 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP07735.1 - 0.035 14.3 0.1 0.12 12.5 0.1 1.9 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KFP07736.1 - 2.2e-14 53.5 0.0 2.7e-14 53.3 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP07736.1 - 1.4e-07 32.0 0.6 6.9e-07 29.8 0.6 1.8 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP07736.1 - 6.7e-06 26.2 0.1 8.5e-05 22.7 0.1 2.0 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP07736.1 - 1.2e-05 25.3 0.1 3.7e-05 23.7 0.1 1.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP07736.1 - 0.0025 18.1 0.1 0.005 17.2 0.1 1.4 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP07737.1 - 1.5e-14 54.1 0.2 1.6e-14 54.0 0.2 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP07737.1 - 8.7e-08 32.7 1.1 2.5e-07 31.2 1.1 1.6 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP07737.1 - 9.1e-05 22.6 0.3 0.00029 20.9 0.3 1.7 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP07737.1 - 0.00011 22.2 0.0 0.0018 18.3 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP07737.1 - 0.0016 18.8 0.9 0.0028 18.0 0.9 1.4 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP07738.1 - 4.3e-06 26.9 0.0 4.8e-06 26.7 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP07738.1 - 0.023 15.3 0.2 0.067 13.8 0.2 1.7 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KFP07739.1 - 1.3e-13 51.0 0.1 1.5e-13 50.9 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP07739.1 - 2.5e-07 31.2 0.4 7e-07 29.8 0.4 1.6 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP07739.1 - 1.1e-06 28.5 0.0 8.7e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP07739.1 - 0.0047 17.2 0.3 0.0089 16.3 0.3 1.4 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP07739.1 - 0.02 15.1 0.3 0.1 12.7 0.3 1.9 1 1 0 1 1 1 0 Immunoglobulin domain G6B PF15096.6 KFP07739.1 - 0.057 13.2 0.0 0.086 12.6 0.0 1.4 1 1 0 1 1 1 0 G6B family DUF5008 PF16400.5 KFP07739.1 - 0.062 13.4 0.0 0.077 13.1 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5008) DNA_ligase_ZBD PF03119.16 KFP07739.1 - 0.17 12.0 0.0 0.49 10.5 0.0 1.7 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Carb_anhydrase PF00194.21 KFP07740.1 - 6.9e-85 284.6 0.0 7.6e-85 284.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Lectin_C PF00059.21 KFP07741.1 - 5.8e-21 75.3 0.7 9.9e-21 74.5 0.7 1.4 1 0 0 1 1 1 1 Lectin C-type domain Ldl_recept_a PF00057.18 KFP07741.1 - 3.2e-11 43.3 7.9 3.2e-11 43.3 7.9 3.5 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A UL45 PF05473.12 KFP07741.1 - 0.0012 18.5 0.4 0.0026 17.4 0.0 1.7 2 0 0 2 2 2 1 UL45 protein, carbohydrate-binding C-type lectin-like Es2 PF09751.9 KFP07742.1 - 1.9e-69 235.5 6.8 1.9e-69 235.5 6.8 2.4 1 1 1 2 2 2 1 Nuclear protein Es2 RED_C PF07807.11 KFP07742.1 - 0.54 10.7 3.8 0.23 11.9 0.3 2.2 3 1 0 3 3 3 0 RED-like protein C-terminal region Homeodomain PF00046.29 KFP07743.1 - 2.1e-22 78.7 5.3 3.2e-22 78.1 5.3 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP07743.1 - 0.0057 16.5 0.1 0.017 15.0 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain DUF3437 PF11919.8 KFP07743.1 - 0.091 12.7 0.9 0.44 10.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) TSP_1 PF00090.19 KFP07745.1 - 9.4e-10 38.6 6.2 9.4e-10 38.6 6.2 2.4 2 1 0 2 2 2 1 Thrombospondin type 1 domain Somatomedin_B PF01033.17 KFP07745.1 - 3.6e-06 27.3 19.9 3.6e-06 27.3 19.9 2.4 3 0 0 3 3 3 1 Somatomedin B domain Mito_carr PF00153.27 KFP07746.1 - 1.2e-61 204.6 0.2 3.7e-20 71.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Clathrin PF00637.20 KFP07747.1 - 3.2e-211 691.7 44.8 1.1e-34 119.4 2.7 7.9 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KFP07747.1 - 1.6e-48 160.7 1.6 1.3e-09 37.9 0.0 6.6 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 KFP07747.1 - 1.9e-30 104.6 1.8 9.1e-30 102.4 0.3 2.9 3 0 0 3 3 3 1 Clathrin-H-link Clathrin-link PF09268.10 KFP07747.1 - 4.7e-11 41.8 0.4 1.5e-10 40.2 0.4 2.0 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 KFP07747.1 - 0.00016 20.9 4.0 0.0013 17.8 0.1 3.8 3 1 0 4 4 4 1 Coatomer WD associated region TPR_19 PF14559.6 KFP07747.1 - 0.0053 17.2 4.3 38 4.9 0.2 6.4 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP07747.1 - 0.039 14.0 12.2 1.3 9.3 0.3 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF5082 PF16888.5 KFP07748.1 - 5.2e-05 23.5 5.8 0.00032 21.0 2.8 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF5082) DUF1664 PF07889.12 KFP07748.1 - 0.006 16.6 3.2 0.39 10.8 0.8 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) COG5 PF10392.9 KFP07748.1 - 0.023 14.9 2.8 0.09 13.0 0.2 2.6 3 0 0 3 3 3 0 Golgi transport complex subunit 5 V-SNARE_C PF12352.8 KFP07748.1 - 0.03 14.6 5.8 0.082 13.2 0.5 3.0 3 1 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus KxDL PF10241.9 KFP07748.1 - 0.033 14.4 8.6 0.14 12.4 0.1 3.0 3 1 1 4 4 4 0 Uncharacterized conserved protein DUF745 PF05335.13 KFP07748.1 - 0.047 13.4 2.1 0.32 10.7 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF745) DUF677 PF05055.12 KFP07748.1 - 0.16 10.8 4.4 2.4 7.0 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF677) DUF948 PF06103.11 KFP07748.1 - 0.22 11.8 1.8 4.2 7.7 0.6 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) BRE1 PF08647.11 KFP07748.1 - 0.26 11.4 9.8 1.6 8.8 0.2 3.0 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase Fib_alpha PF08702.10 KFP07748.1 - 0.32 11.2 7.8 6.1 7.0 0.5 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 KFP07748.1 - 0.36 10.1 1.7 7.7 5.8 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DASH_Duo1 PF08651.10 KFP07748.1 - 0.49 10.2 0.1 0.49 10.2 0.1 2.5 3 0 0 3 3 3 0 DASH complex subunit Duo1 DUF2203 PF09969.9 KFP07748.1 - 0.56 10.9 2.8 11 6.8 2.8 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) FliJ PF02050.16 KFP07748.1 - 1.1 9.5 5.7 1.6 9.0 0.3 2.7 2 1 1 3 3 3 0 Flagellar FliJ protein DUF641 PF04859.12 KFP07748.1 - 1.6 9.1 6.0 13 6.1 2.2 2.6 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) Holin_BhlA PF10960.8 KFP07748.1 - 1.8 8.6 7.6 0.43 10.6 0.3 2.9 3 0 0 3 3 3 0 BhlA holin family Uds1 PF15456.6 KFP07748.1 - 2.2 8.4 8.2 9.4 6.4 3.9 2.8 2 1 0 2 2 2 0 Up-regulated During Septation DUF5089 PF17002.5 KFP07748.1 - 3.1 7.6 10.4 1.5e+02 2.1 10.4 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5089) SNARE PF05739.19 KFP07748.1 - 3.4 7.8 6.7 23 5.1 0.2 3.6 4 0 0 4 4 4 0 SNARE domain DUF16 PF01519.16 KFP07748.1 - 4.8 7.7 10.2 1.8e+02 2.7 9.5 2.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 XhlA PF10779.9 KFP07748.1 - 8.8 6.6 12.2 4.7 7.5 0.1 3.5 3 1 0 3 3 3 0 Haemolysin XhlA UPF0242 PF06785.11 KFP07748.1 - 9.7 6.2 10.1 43 4.1 10.0 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PI3_PI4_kinase PF00454.27 KFP07749.1 - 2.3e-41 142.3 0.4 3.1e-28 99.2 0.4 2.8 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KFP07749.1 - 8.6e-35 119.8 0.0 2.1e-34 118.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4441 PF14536.6 KFP07749.1 - 0.024 14.8 0.2 0.19 11.9 0.2 2.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) Ribosomal_L18_c PF14204.6 KFP07749.1 - 0.14 13.1 0.2 0.34 11.9 0.2 1.7 1 0 0 1 1 1 0 Ribosomal L18 C-terminal region Serpin PF00079.20 KFP07750.1 - 3.4e-110 368.8 2.3 4.5e-110 368.4 2.3 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) BTB PF00651.31 KFP07751.1 - 8.4e-27 93.6 0.4 1.3e-26 93.0 0.4 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 KFP07751.1 - 1.3e-26 91.5 24.4 7.4e-06 26.1 1.3 6.0 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP07751.1 - 2.4e-23 80.8 22.7 0.00032 21.3 0.5 5.9 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP07751.1 - 2.7e-19 68.7 30.8 5.8e-08 32.8 0.2 7.4 6 1 0 6 6 6 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFP07751.1 - 6.9e-16 58.1 3.4 0.00027 21.1 0.3 5.9 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP07751.1 - 2.1e-11 43.8 13.3 0.0035 17.7 0.4 5.8 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFP07751.1 - 3.3e-10 39.7 21.5 0.018 15.0 0.3 6.0 5 1 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KFP07751.1 - 1e-05 26.2 5.6 0.0028 18.3 0.3 4.2 1 1 2 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 KFP07751.1 - 8.7e-05 22.2 16.6 0.23 11.2 0.4 4.6 5 0 0 5 5 4 3 zinc-finger C2H2-type zf-Di19 PF05605.12 KFP07751.1 - 0.00029 21.1 11.3 0.05 13.9 0.6 3.7 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 KFP07751.1 - 0.0012 19.1 10.2 9.6 6.6 1.3 4.5 2 1 2 4 4 4 0 C2H2-type zinc ribbon zf_C2H2_ZHX PF18387.1 KFP07751.1 - 0.0017 17.9 4.4 2 8.1 0.0 3.7 3 0 0 3 3 3 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HE PF16278.5 KFP07751.1 - 0.0022 18.4 15.9 0.18 12.3 0.4 5.5 1 1 4 5 5 5 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 KFP07751.1 - 0.0022 18.3 14.5 7.8 6.9 0.3 5.1 1 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-UBP PF02148.19 KFP07751.1 - 0.0066 16.8 6.0 2.5 8.5 0.1 3.7 2 1 1 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein zf-AN1 PF01428.16 KFP07751.1 - 0.047 13.8 10.1 27 5.0 0.1 4.6 4 0 0 4 4 4 0 AN1-like Zinc finger zf-MYST PF17772.1 KFP07751.1 - 0.072 12.7 0.2 12 5.6 0.0 3.5 3 0 0 3 3 3 0 MYST family zinc finger domain GAGA PF09237.11 KFP07751.1 - 0.13 12.1 4.1 1.6 8.6 0.2 3.1 2 1 1 3 3 3 0 GAGA factor RhlB PF12300.8 KFP07751.1 - 0.14 12.3 1.1 0.32 11.1 1.1 1.6 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB zf-H2C2_5 PF13909.6 KFP07751.1 - 0.27 11.0 22.1 4.6 7.1 0.1 5.7 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-BED PF02892.15 KFP07751.1 - 0.32 11.0 16.7 2 8.5 3.7 5.0 4 1 1 5 5 5 0 BED zinc finger zf_UBZ PF18439.1 KFP07751.1 - 0.38 10.4 14.3 3.2 7.4 0.1 5.3 6 0 0 6 6 5 0 Ubiquitin-Binding Zinc Finger C1_1 PF00130.22 KFP07751.1 - 0.85 9.6 7.4 1.1 9.1 1.4 3.4 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.21 KFP07751.1 - 1 9.6 9.1 2e+02 2.2 9.1 2.9 1 1 0 1 1 1 0 FYVE zinc finger zinc_ribbon_15 PF17032.5 KFP07751.1 - 1.1 10.0 8.8 4.7 8.0 0.6 3.5 1 1 0 2 2 2 0 zinc-ribbon family zf-HYPF PF07503.12 KFP07751.1 - 3 7.7 7.0 17 5.3 0.4 3.3 3 1 0 3 3 3 0 HypF finger LIM PF00412.22 KFP07751.1 - 3.3 8.0 12.9 0.24 11.7 0.5 3.7 3 1 2 5 5 3 0 LIM domain zf-RING_5 PF14634.6 KFP07751.1 - 6.6 6.8 8.4 1.1e+02 2.9 0.1 3.7 2 1 0 2 2 2 0 zinc-RING finger domain Zn-ribbon_8 PF09723.10 KFP07751.1 - 8.3 6.6 14.4 3.6 7.8 4.3 4.1 2 1 3 5 5 5 0 Zinc ribbon domain zf-LYAR PF08790.11 KFP07751.1 - 8.4 6.4 11.6 2.2 8.3 0.1 4.5 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger UQ_con PF00179.26 KFP07752.1 - 5.3e-44 149.3 0.4 6e-44 149.1 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFP07752.1 - 3.7e-05 24.0 0.1 5.1e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KFP07752.1 - 3.9e-05 23.4 0.0 4.9e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KFP07752.1 - 4.2e-05 23.4 0.1 7.4e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 UEV domain YdjC PF04794.12 KFP07753.1 - 1.1e-14 55.0 0.0 1.2e-14 54.9 0.0 1.0 1 0 0 1 1 1 1 YdjC-like protein MIR PF02815.19 KFP07754.1 - 1.5e-15 57.5 0.1 1.1e-12 48.2 0.1 2.1 1 1 1 2 2 2 2 MIR domain Topoisom_bac PF01131.20 KFP07755.1 - 3.5e-119 398.5 0.0 4.2e-119 398.2 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 KFP07755.1 - 9.3e-14 51.5 0.0 2.1e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Toprim domain DUF2204 PF09970.9 KFP07755.1 - 0.14 11.7 0.1 0.91 9.1 0.0 2.0 2 0 0 2 2 2 0 Nucleotidyl transferase of unknown function (DUF2204) PP2C PF00481.21 KFP07756.1 - 4e-66 223.3 0.0 4.9e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFP07756.1 - 0.0046 16.6 0.3 0.02 14.5 0.3 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.25 KFP07757.1 - 3.2e-63 213.6 0.1 3.7e-63 213.3 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP07757.1 - 6.5e-32 110.8 0.0 9.3e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFP07757.1 - 0.00086 19.3 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFP07757.1 - 0.01 14.8 0.2 0.021 13.8 0.2 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 KFP07757.1 - 0.056 13.0 0.2 0.088 12.4 0.2 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 KFP07757.1 - 0.058 13.0 0.1 0.086 12.4 0.1 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KFP07757.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 KFP07757.1 - 0.089 12.1 0.3 0.13 11.6 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Yippee-Mis18 PF03226.14 KFP07758.1 - 1.1e-12 48.1 0.1 1.3e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 KFP07758.1 - 0.016 15.4 0.2 0.028 14.6 0.2 1.4 1 1 0 1 1 1 0 C-terminal domain of RIG-I Evr1_Alr PF04777.13 KFP07758.1 - 0.057 13.9 2.6 0.43 11.1 2.6 2.0 1 1 0 1 1 1 0 Erv1 / Alr family zf-CHY PF05495.12 KFP07758.1 - 0.076 13.5 6.8 0.27 11.7 6.8 1.9 1 1 0 1 1 1 0 CHY zinc finger Pro_isomerase PF00160.21 KFP07759.1 - 1.1e-51 175.3 0.0 2.2e-51 174.3 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-NOSIP PF15906.5 KFP07759.1 - 0.00033 20.7 0.0 0.00092 19.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 KFP07759.1 - 0.0013 18.1 0.4 0.0013 18.1 0.4 2.9 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.15 KFP07759.1 - 0.0014 18.7 0.0 0.0066 16.6 0.0 2.2 2 0 0 2 2 2 1 U-box domain Hira PF07569.11 KFP07760.1 - 8.2e-58 195.7 0.2 2e-57 194.5 0.2 1.7 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 KFP07760.1 - 2.9e-28 97.5 31.9 2.5e-08 34.4 4.0 8.6 8 1 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP07760.1 - 2.4e-11 43.8 4.5 0.013 15.8 0.0 6.1 4 1 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 KFP07760.1 - 4.5e-08 32.8 0.0 1.2e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 HIRA B motif TFIIIC_delta PF12657.7 KFP07760.1 - 0.024 14.6 2.5 0.6 10.0 0.1 3.6 3 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term WD40_like PF17005.5 KFP07760.1 - 0.071 12.4 0.0 0.55 9.5 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain MRP-L28 PF09812.9 KFP07761.1 - 2.3e-48 164.4 7.6 2.7e-48 164.2 7.6 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 DUF4207 PF13904.6 KFP07761.1 - 0.0037 17.0 9.1 0.0051 16.5 9.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) UFD1 PF03152.14 KFP07762.1 - 6e-80 266.8 0.0 7.2e-80 266.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 KFP07762.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 CDC45 PF02724.14 KFP07763.1 - 2.7e-158 528.2 19.2 1.2e-154 516.1 19.2 3.0 1 1 0 1 1 1 1 CDC45-like protein ROQ_II PF18386.1 KFP07763.1 - 0.088 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Roquin II domain DUF3848 PF12959.7 KFP07763.1 - 0.1 12.7 0.9 0.27 11.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) DUF4611 PF15387.6 KFP07763.1 - 0.26 11.5 5.4 0.65 10.3 5.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) UBA2_C PF16195.5 KFP07763.1 - 0.31 11.8 5.9 5.7 7.7 5.0 2.4 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus Septin PF00735.18 KFP07764.1 - 7.1e-126 419.2 0.0 8.9e-126 418.9 0.0 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFP07764.1 - 2.8e-08 33.8 0.0 9.7e-08 32.1 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP07764.1 - 6.5e-06 25.8 0.1 0.0027 17.3 0.0 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KFP07764.1 - 4.5e-05 22.9 0.9 0.00012 21.5 0.0 2.0 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 KFP07764.1 - 4.8e-05 23.3 1.2 0.0011 18.9 0.3 2.6 2 1 0 2 2 2 1 RsgA GTPase Ras PF00071.22 KFP07764.1 - 8.1e-05 22.3 0.0 0.00026 20.6 0.0 1.9 1 1 0 1 1 1 1 Ras family Dynamin_N PF00350.23 KFP07764.1 - 0.00036 20.6 2.1 0.13 12.3 0.0 2.9 2 1 0 3 3 3 2 Dynamin family AAA_22 PF13401.6 KFP07764.1 - 0.0026 18.0 1.3 0.011 16.1 0.1 2.7 2 2 0 2 2 2 1 AAA domain Roc PF08477.13 KFP07764.1 - 0.0032 17.7 0.0 0.0062 16.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KFP07764.1 - 0.0057 17.1 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KFP07764.1 - 0.0087 15.6 0.1 0.022 14.2 0.0 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region Gtr1_RagA PF04670.12 KFP07764.1 - 0.0099 15.3 0.1 0.055 12.8 0.0 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 KFP07764.1 - 0.019 14.7 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KFP07764.1 - 0.026 15.0 2.3 0.032 14.7 0.2 2.1 2 1 0 2 2 2 0 ABC transporter G-alpha PF00503.20 KFP07764.1 - 0.056 12.6 0.0 4.5 6.3 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit Sec2p PF06428.11 KFP07764.1 - 0.16 11.9 4.2 0.31 11.0 3.5 1.9 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p AAA_28 PF13521.6 KFP07764.1 - 0.46 10.7 2.6 20 5.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain Septin PF00735.18 KFP07765.1 - 7.5e-131 435.5 0.4 8.5e-131 435.4 0.4 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFP07765.1 - 1.7e-08 34.5 0.0 3.4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP07765.1 - 1.2e-07 31.7 0.2 1.7e-05 24.8 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KFP07765.1 - 1.1e-05 25.0 0.2 0.028 13.9 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KFP07765.1 - 0.00094 18.6 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KFP07765.1 - 0.0032 17.6 1.9 0.38 10.8 0.0 2.6 1 1 1 2 2 2 2 Dynamin family Ras PF00071.22 KFP07765.1 - 0.0079 15.8 0.1 0.018 14.7 0.1 1.6 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP07765.1 - 0.014 15.7 0.1 0.026 14.8 0.1 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KFP07765.1 - 0.015 15.7 0.0 0.028 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KFP07765.1 - 0.035 13.9 0.1 0.086 12.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KFP07765.1 - 0.038 14.5 0.2 0.058 13.9 0.2 1.6 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KFP07765.1 - 0.053 13.8 0.0 0.13 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFP07765.1 - 0.13 11.8 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 KFP07765.1 - 0.32 11.4 3.5 1.6 9.2 3.5 1.9 1 1 0 1 1 1 0 AAA domain LRR_8 PF13855.6 KFP07766.1 - 1e-05 25.2 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Leucine rich repeat LRRNT PF01462.18 KFP07766.1 - 2.8e-05 23.7 1.7 2.8e-05 23.7 1.7 2.5 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.7 KFP07766.1 - 0.00017 21.9 0.1 0.00033 21.0 0.1 1.5 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) DUF948 PF06103.11 KFP07766.1 - 0.0066 16.7 0.1 0.013 15.7 0.1 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) TssO PF17561.2 KFP07766.1 - 0.025 14.7 0.8 0.04 14.0 0.8 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssO T-box PF00907.22 KFP07767.1 - 3.6e-65 219.7 0.2 4.3e-65 219.4 0.2 1.1 1 0 0 1 1 1 1 T-box WD40 PF00400.32 KFP07768.1 - 2.3e-22 78.8 8.4 0.0015 19.3 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP07768.1 - 2.5e-07 30.9 0.8 0.045 14.1 0.1 4.3 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Pyr_redox_2 PF07992.14 KFP07769.1 - 7.9e-50 169.7 0.1 2.6e-49 168.1 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFP07769.1 - 8.1e-31 106.5 0.0 1.6e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFP07769.1 - 6.3e-14 52.3 0.4 7.2e-09 36.1 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFP07769.1 - 7.2e-08 31.9 5.6 5.7e-07 29.0 0.8 3.0 2 2 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.6 KFP07769.1 - 1.9e-06 27.3 2.0 0.025 13.9 0.1 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFP07769.1 - 1e-05 24.9 0.4 0.0077 15.4 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KFP07769.1 - 0.00013 20.8 2.0 0.0011 17.8 0.3 2.4 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 KFP07769.1 - 0.00023 20.5 0.0 0.0004 19.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KFP07769.1 - 0.00026 20.2 2.7 0.0013 17.9 2.6 2.0 1 1 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 KFP07769.1 - 0.0011 18.7 3.6 0.004 16.8 0.5 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFP07769.1 - 0.0013 18.9 0.3 0.0038 17.4 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KFP07769.1 - 0.0015 18.0 2.4 0.0015 18.0 2.4 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KFP07769.1 - 0.0069 15.7 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF1775 PF07987.11 KFP07769.1 - 0.016 15.5 0.6 3.7 7.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unkown function (DUF1775) Lycopene_cycl PF05834.12 KFP07769.1 - 0.18 10.8 1.5 0.45 9.5 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Methyltransf_3 PF01596.17 KFP07770.1 - 2.8e-22 78.9 0.0 3.8e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KFP07770.1 - 3.6e-14 53.7 0.0 5.1e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 KFP07770.1 - 0.00018 21.3 0.0 0.00026 20.7 0.0 1.2 1 0 0 1 1 1 1 Cephalosporin hydroxylase PCMT PF01135.19 KFP07770.1 - 0.0006 19.6 0.0 0.00093 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KFP07770.1 - 0.0024 17.7 0.0 0.0065 16.3 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KFP07770.1 - 0.086 12.5 0.1 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Arm PF00514.23 KFP07771.1 - 1.4e-39 132.9 0.9 1.8e-08 34.1 0.0 7.6 7 0 0 7 7 7 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KFP07771.1 - 1e-10 41.9 1.2 0.24 11.9 0.1 5.3 5 0 0 5 5 5 3 HEAT-like repeat HEAT_2 PF13646.6 KFP07771.1 - 1.4e-10 41.4 0.3 0.00014 22.2 0.0 3.2 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.22 KFP07771.1 - 2e-09 36.9 0.7 0.66 10.4 0.0 5.2 5 0 0 5 5 5 3 HEAT repeat Arm_2 PF04826.13 KFP07771.1 - 5.9e-06 25.9 0.2 0.02 14.3 0.0 3.7 2 2 1 4 4 4 2 Armadillo-like Atx10homo_assoc PF09759.9 KFP07771.1 - 0.00016 21.7 0.1 0.0072 16.3 0.0 2.8 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Cnd1 PF12717.7 KFP07771.1 - 0.002 18.2 0.1 0.38 10.8 0.1 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 UNC45-central PF11701.8 KFP07771.1 - 0.13 12.2 0.8 10 6.0 0.0 3.1 2 1 0 3 3 3 0 Myosin-binding striated muscle assembly central TANGO2 PF05742.12 KFP07772.1 - 2.5e-05 24.5 0.0 2.5e-05 24.5 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 dsrm PF00035.26 KFP07773.1 - 2.2e-20 73.1 3.4 2.6e-12 47.3 0.0 3.8 3 1 0 3 3 3 2 Double-stranded RNA binding motif WW PF00397.26 KFP07773.1 - 0.012 15.7 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 WW domain Ran_BP1 PF00638.18 KFP07774.1 - 9.5e-55 184.1 0.4 9.5e-55 184.1 0.4 1.6 2 0 0 2 2 2 1 RanBP1 domain DUF883 PF05957.13 KFP07774.1 - 0.11 13.1 2.3 9.3 6.9 1.2 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) His_Phos_1 PF00300.22 KFP07775.1 - 5.1e-22 78.5 0.1 3.2e-20 72.7 0.1 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AbfS_sensor PF18225.1 KFP07775.1 - 0.098 12.6 0.2 0.79 9.7 0.0 2.1 2 0 0 2 2 2 0 Sensor histidine kinase (AbfS) sensor domain LEM PF03020.15 KFP07776.1 - 1.9e-11 43.3 0.8 5.9e-11 41.8 0.0 2.1 2 0 0 2 2 2 1 LEM domain Ank_5 PF13857.6 KFP07776.1 - 1.3e-08 35.0 0.0 0.004 17.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP07776.1 - 1.9e-06 28.3 0.0 1.8e-05 25.2 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Cauli_VI PF01693.16 KFP07776.1 - 6.6e-05 23.1 0.6 0.00026 21.3 0.1 2.2 2 0 0 2 2 2 1 Caulimovirus viroplasmin Ank_4 PF13637.6 KFP07776.1 - 0.00013 22.5 0.1 0.00073 20.1 0.1 2.2 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP07776.1 - 0.00029 21.0 0.0 0.11 13.1 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 KFP07776.1 - 0.0025 18.2 0.0 0.29 11.7 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat ATG16 PF08614.11 KFP07777.1 - 0.0015 18.8 26.4 0.0015 18.8 26.4 11.6 2 2 9 11 11 11 4 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 KFP07777.1 - 0.0035 17.5 18.7 0.0035 17.5 18.7 14.4 3 1 10 15 15 15 3 TATA element modulatory factor 1 TATA binding zf-CRD PF17979.1 KFP07779.1 - 7.3e-46 156.2 11.4 7.3e-46 156.2 11.4 3.2 3 0 0 3 3 3 1 Cysteine rich domain with multizinc binding regions FHA PF00498.26 KFP07779.1 - 5.1e-16 58.8 0.1 1.1e-15 57.7 0.1 1.6 1 0 0 1 1 1 1 FHA domain zf-C3HC4_2 PF13923.6 KFP07779.1 - 4e-08 33.0 14.0 4e-08 33.0 14.0 4.3 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-CCHH PF10283.9 KFP07779.1 - 6.5e-08 32.4 4.1 6.5e-08 32.4 4.1 2.0 2 0 0 2 2 2 1 PBZ domain zf-RING_2 PF13639.6 KFP07779.1 - 5.1e-07 29.9 13.4 5.1e-07 29.9 13.4 4.2 4 0 0 4 4 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFP07779.1 - 7.6e-07 28.9 13.6 7.6e-07 28.9 13.6 4.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 KFP07779.1 - 1.7e-06 28.2 0.0 4.9e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4 PF00097.25 KFP07779.1 - 2.6e-05 24.0 13.2 2.6e-05 24.0 13.2 3.9 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFP07779.1 - 0.0003 21.0 9.6 0.0003 21.0 9.6 3.2 3 0 0 3 3 2 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KFP07779.1 - 0.0044 16.9 8.7 0.0044 16.9 8.7 3.3 3 0 0 3 3 3 1 zf-RING of BARD1-type protein FHA_2 PF17913.1 KFP07779.1 - 0.0054 16.9 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_UBOX PF13445.6 KFP07779.1 - 0.0099 15.9 15.1 0.0099 15.9 15.1 3.9 4 0 0 4 4 2 1 RING-type zinc-finger Cnl2_NKP2 PF09447.10 KFP07779.1 - 0.014 15.6 0.1 0.44 10.7 0.1 2.5 2 0 0 2 2 2 0 Cnl2/NKP2 family protein zf-RING_5 PF14634.6 KFP07779.1 - 2.3 8.3 34.5 0.026 14.5 15.1 3.7 3 0 0 3 3 2 0 zinc-RING finger domain Auts2 PF15336.6 KFP07780.1 - 4.7e-110 366.9 11.6 4.7e-110 366.9 11.6 5.7 6 1 0 7 7 7 3 Autism susceptibility gene 2 protein Glycos_transf_2 PF00535.26 KFP07782.1 - 4.8e-26 91.6 0.1 9.7e-26 90.6 0.1 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFP07782.1 - 1.9e-20 73.4 0.0 3e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 KFP07782.1 - 1.5e-06 28.3 0.0 1.8e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KFP07782.1 - 0.0059 16.2 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase CBF PF03914.17 KFP07783.1 - 6.4e-36 123.9 1.5 1e-35 123.2 1.5 1.3 1 0 0 1 1 1 1 CBF/Mak21 family EP400_N PF15790.5 KFP07784.1 - 1.3e-277 921.4 40.3 1.3e-277 921.4 40.3 6.4 4 1 1 5 5 5 1 E1A-binding protein p400, N-terminal SNF2_N PF00176.23 KFP07784.1 - 2.6e-48 164.6 2.7 2.6e-48 164.6 2.7 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain HSA PF07529.13 KFP07784.1 - 5.3e-20 71.5 11.3 5.3e-20 71.5 11.3 3.8 4 1 1 5 5 5 1 HSA Helicase_C PF00271.31 KFP07784.1 - 9.2e-09 35.6 0.1 3e-08 34.0 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Myb_DNA-binding PF00249.31 KFP07784.1 - 4.8e-05 23.5 0.0 0.00021 21.4 0.0 2.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KFP07784.1 - 0.0023 18.2 0.0 0.0023 18.2 0.0 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFP07784.1 - 0.0044 17.2 2.8 0.0077 16.5 0.1 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain PseudoU_synth_1 PF01416.20 KFP07785.1 - 9.6e-15 55.0 0.0 2.7e-13 50.3 0.0 2.3 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF2344 PF10105.9 KFP07785.1 - 0.074 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) MPC PF03650.13 KFP07786.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial pyruvate carriers Pkinase PF00069.25 KFP07787.1 - 3.8e-66 223.1 2.9 4.7e-66 222.8 0.1 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP07787.1 - 2.3e-49 168.0 0.0 4.5e-49 167.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 KFP07787.1 - 7.9e-26 90.9 6.0 2e-25 89.6 6.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Kdo PF06293.14 KFP07787.1 - 1.2e-06 28.0 0.0 2.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFP07787.1 - 7.9e-05 22.3 0.1 0.00014 21.5 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KFP07787.1 - 0.0007 19.0 0.0 0.0053 16.1 0.0 2.3 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFP07787.1 - 0.0015 17.4 0.0 0.0034 16.2 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP07787.1 - 0.015 15.3 0.0 0.079 12.9 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Peptidase_M10 PF00413.24 KFP07788.1 - 6.7e-50 169.0 0.5 1.3e-49 168.0 0.5 1.5 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 KFP07788.1 - 6.3e-47 157.3 22.2 1.9e-13 50.1 0.3 5.1 5 0 0 5 5 5 4 Hemopexin PG_binding_1 PF01471.18 KFP07788.1 - 1.6e-12 47.4 0.1 3.5e-12 46.4 0.1 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.24 KFP07788.1 - 0.028 14.0 1.1 0.61 9.7 0.9 2.2 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Peptidase_M66 PF10462.9 KFP07788.1 - 0.048 12.6 0.1 0.077 11.9 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 DRY_EERY PF09750.9 KFP07789.1 - 1.4e-33 116.0 2.2 1.4e-33 116.0 2.2 4.5 5 2 0 5 5 5 1 Alternative splicing regulator Surp PF01805.20 KFP07789.1 - 1.5e-26 92.1 7.6 4.1e-13 49.1 0.9 2.5 2 0 0 2 2 2 2 Surp module Bindin PF02084.15 KFP07789.1 - 0.032 14.5 0.2 0.14 12.4 0.2 2.1 1 0 0 1 1 1 0 Bindin FANCM-MHF_bd PF16783.5 KFP07789.1 - 4.1 7.5 8.9 0.12 12.5 1.0 2.6 2 0 0 2 2 2 0 FANCM to MHF binding domain 7tm_2 PF00002.24 KFP07790.1 - 8.6e-55 185.7 19.1 8.6e-55 185.7 19.1 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Laminin_G_3 PF13385.6 KFP07790.1 - 5.5e-16 59.1 0.1 9.6e-16 58.3 0.1 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Dicty_CAR PF05462.11 KFP07790.1 - 1.7e-07 30.7 15.6 3e-07 29.9 15.6 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Pentaxin PF00354.17 KFP07790.1 - 0.035 13.8 0.0 0.087 12.5 0.0 1.6 1 0 0 1 1 1 0 Pentaxin family Ras PF00071.22 KFP07791.1 - 5.9e-50 169.0 0.0 7e-50 168.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP07791.1 - 4.2e-31 107.6 0.0 8.4e-31 106.7 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP07791.1 - 1.4e-11 44.2 0.0 1.7e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP07791.1 - 9.9e-05 22.4 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KFP07791.1 - 0.00026 21.4 0.1 0.00094 19.5 0.1 1.8 1 1 0 1 1 1 1 RNA helicase GTP_EFTU PF00009.27 KFP07791.1 - 0.00081 19.0 0.4 0.0035 16.9 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFP07791.1 - 0.0012 18.2 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KFP07791.1 - 0.0076 15.4 1.7 1 8.5 0.1 2.9 2 1 1 3 3 3 1 G-protein alpha subunit SRPRB PF09439.10 KFP07791.1 - 0.0092 15.4 0.0 0.015 14.7 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 KFP07791.1 - 0.013 15.3 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 KFP07791.1 - 0.013 15.0 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 KFP07791.1 - 0.021 14.4 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ArgoMid PF16487.5 KFP07791.1 - 0.03 14.6 0.1 0.054 13.8 0.1 1.4 1 0 0 1 1 1 0 Mid domain of argonaute Septin PF00735.18 KFP07791.1 - 0.036 13.3 0.0 0.06 12.6 0.0 1.4 1 0 0 1 1 1 0 Septin RsgA_GTPase PF03193.16 KFP07791.1 - 0.066 13.1 0.1 8.7 6.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 KFP07791.1 - 0.071 13.1 0.1 0.14 12.1 0.1 1.5 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 KFP07791.1 - 0.072 13.5 0.0 0.099 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KFP07791.1 - 0.11 12.7 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain Syntaxin PF00804.25 KFP07792.1 - 8.3e-62 208.4 16.7 8.3e-62 208.4 16.7 1.4 2 0 0 2 2 1 1 Syntaxin SNARE PF05739.19 KFP07792.1 - 2.8e-18 65.6 1.9 2.8e-18 65.6 1.9 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 KFP07792.1 - 1.4e-11 44.6 6.0 1.4e-11 44.6 6.0 2.6 2 2 0 2 2 2 1 Syntaxin-like protein T2SSF PF00482.23 KFP07792.1 - 0.0016 18.4 3.5 0.018 15.0 0.6 2.7 2 1 0 2 2 2 1 Type II secretion system (T2SS), protein F DUF1640 PF07798.11 KFP07792.1 - 0.002 18.2 2.4 0.002 18.2 2.4 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1640) DUF3671 PF12420.8 KFP07792.1 - 0.0021 18.1 0.4 0.0021 18.1 0.4 2.3 3 0 0 3 3 1 1 Protein of unknown function COG5 PF10392.9 KFP07792.1 - 0.0021 18.2 6.7 0.38 10.9 0.9 2.7 2 1 0 2 2 2 2 Golgi transport complex subunit 5 AAA_27 PF13514.6 KFP07792.1 - 0.0062 16.1 4.3 0.098 12.2 0.7 2.1 2 0 0 2 2 2 1 AAA domain Syntaxin-6_N PF09177.11 KFP07792.1 - 0.02 15.4 1.4 0.02 15.4 1.4 2.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF16 PF01519.16 KFP07792.1 - 0.023 15.2 0.7 0.023 15.2 0.7 3.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 AAA_13 PF13166.6 KFP07792.1 - 0.032 12.9 17.5 0.049 12.3 17.1 1.5 1 1 0 1 1 1 0 AAA domain DUF4855 PF16147.5 KFP07792.1 - 0.038 13.1 0.5 0.038 13.1 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4855) LPP PF04728.13 KFP07792.1 - 0.048 14.1 7.2 9.3 6.7 0.2 3.7 3 1 0 3 3 3 0 Lipoprotein leucine-zipper Baculo_PEP_C PF04513.12 KFP07792.1 - 0.049 13.7 2.6 0.46 10.5 0.3 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1845 PF08900.11 KFP07792.1 - 0.07 12.9 3.1 0.13 12.0 0.1 2.5 3 1 0 3 3 2 0 Domain of unknown function (DUF1845) Lipase_GDSL PF00657.22 KFP07792.1 - 0.071 13.1 3.2 0.15 12.0 3.2 1.9 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Ntox16 PF15523.6 KFP07792.1 - 0.12 12.6 0.5 0.35 11.1 0.5 1.9 1 1 0 1 1 1 0 Novel toxin 16 DUF2205 PF10224.9 KFP07792.1 - 0.13 12.3 0.2 0.13 12.3 0.2 3.8 4 0 0 4 4 4 0 Short coiled-coil protein Serine_rich PF08824.10 KFP07792.1 - 0.21 11.5 3.2 0.62 10.1 0.5 2.3 2 0 0 2 2 2 0 Serine rich protein interaction domain Prominin PF05478.11 KFP07792.1 - 0.23 9.4 15.3 0.04 11.9 2.3 2.1 1 1 0 2 2 2 0 Prominin Nas2_N PF18265.1 KFP07792.1 - 0.28 11.1 5.7 1.1 9.2 0.0 3.4 3 1 0 3 3 3 0 Nas2 N_terminal domain FapA PF03961.13 KFP07792.1 - 0.32 9.6 17.8 0.0079 14.8 7.5 2.1 1 1 0 2 2 2 0 Flagellar Assembly Protein A DUF677 PF05055.12 KFP07792.1 - 0.44 9.4 17.2 0.025 13.5 3.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF677) TipAS PF07739.13 KFP07792.1 - 0.49 10.9 4.6 12 6.4 0.4 2.7 2 2 0 2 2 2 0 TipAS antibiotic-recognition domain DUF745 PF05335.13 KFP07792.1 - 0.65 9.7 7.9 5 6.8 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Laminin_II PF06009.12 KFP07792.1 - 0.94 9.5 13.6 3.6 7.6 4.9 3.2 2 1 1 3 3 3 0 Laminin Domain II MCPsignal PF00015.21 KFP07792.1 - 0.96 9.2 12.7 1.7 8.4 0.8 3.3 1 1 4 5 5 5 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Sec34 PF04136.15 KFP07792.1 - 1.1 9.1 13.0 0.49 10.3 4.8 3.0 2 1 1 3 3 3 0 Sec34-like family FlgN PF05130.12 KFP07792.1 - 1.2 9.7 10.6 0.17 12.4 3.7 2.4 1 1 1 3 3 3 0 FlgN protein WXG100 PF06013.12 KFP07792.1 - 1.2 9.4 7.8 12 6.2 0.2 3.8 4 1 1 5 5 4 0 Proteins of 100 residues with WXG DUF2207 PF09972.9 KFP07792.1 - 1.2 7.8 5.0 0.38 9.5 0.2 1.9 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) LPD5 PF18799.1 KFP07792.1 - 1.2 9.5 8.4 1.1 9.7 0.3 2.8 2 1 0 2 2 2 0 Large polyvalent protein-associated domain 5 NPV_P10 PF05531.12 KFP07792.1 - 1.5 9.4 5.5 26 5.4 1.8 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TSC22 PF01166.18 KFP07792.1 - 1.5 9.2 8.5 2.4 8.5 0.1 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family K-box PF01486.17 KFP07792.1 - 2 8.6 12.0 0.19 11.9 3.9 2.8 2 2 0 2 2 2 0 K-box region FlxA PF14282.6 KFP07792.1 - 2 8.4 7.5 0.61 10.1 1.9 2.6 2 1 0 2 2 2 0 FlxA-like protein TMPIT PF07851.13 KFP07792.1 - 2.2 7.4 13.1 0.73 9.0 1.7 2.3 1 1 0 2 2 2 0 TMPIT-like protein Allexi_40kDa PF05549.11 KFP07792.1 - 2.3 7.6 10.0 0.88 9.0 1.9 2.3 1 1 0 2 2 2 0 Allexivirus 40kDa protein Mer2 PF09074.10 KFP07792.1 - 2.5 7.9 17.1 6.7e+02 -0.1 16.8 2.6 1 1 0 1 1 1 0 Mer2 PCRF PF03462.18 KFP07792.1 - 2.5 7.9 17.0 1.2 9.0 2.3 2.8 1 1 2 3 3 3 0 PCRF domain FlaC_arch PF05377.11 KFP07792.1 - 2.6 8.5 14.1 4.8 7.6 0.3 4.4 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF848 PF05852.11 KFP07792.1 - 3.3 7.8 14.1 0.2 11.8 4.7 2.5 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Sulfatase_C PF14707.6 KFP07792.1 - 3.4 8.4 4.5 11 6.8 0.0 3.0 2 1 1 3 3 3 0 C-terminal region of aryl-sulfatase DUF1664 PF07889.12 KFP07792.1 - 4.1 7.5 15.0 25 4.9 0.8 4.0 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) GP41 PF00517.17 KFP07792.1 - 4.8 7.0 13.8 3.3 7.6 1.6 3.5 2 1 2 4 4 4 0 Retroviral envelope protein DUF2203 PF09969.9 KFP07792.1 - 5.7 7.7 12.0 2 9.2 2.6 2.8 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) Atg14 PF10186.9 KFP07792.1 - 6.5 5.7 10.4 2.4 7.2 4.4 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 LUC7 PF03194.15 KFP07792.1 - 8.8 5.9 15.1 0.74 9.4 5.1 2.2 1 1 0 2 2 2 0 LUC7 N_terminus HSCB_C PF07743.13 KFP07792.1 - 9.4 6.8 12.5 0.35 11.4 1.0 3.6 3 1 0 3 3 3 0 HSCB C-terminal oligomerisation domain SH3_2 PF07653.17 KFP07793.1 - 1.3e-32 111.2 0.0 2.1e-10 40.1 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_9 PF14604.6 KFP07793.1 - 1e-27 95.7 3.4 3.6e-12 45.9 0.1 3.9 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 KFP07793.1 - 3.4e-16 58.6 0.1 2e-06 27.3 0.0 4.1 3 1 0 3 3 3 3 SH3 domain fn3 PF00041.21 KFP07793.1 - 6e-13 49.0 5.3 0.00028 21.2 0.3 4.2 3 1 0 3 3 3 3 Fibronectin type III domain CENP-H PF05837.12 KFP07793.1 - 4.2 7.8 9.4 11 6.5 9.4 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ADIP PF11559.8 KFP07793.1 - 4.7 7.3 12.1 9.7 6.3 12.1 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Piwi PF02171.17 KFP07794.1 - 7.9e-106 353.7 0.0 1.3e-105 353.0 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 KFP07794.1 - 1e-34 119.3 0.0 2.3e-34 118.1 0.0 1.5 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 KFP07794.1 - 5.6e-07 30.2 0.0 1.8e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KFP07794.1 - 1.3e-05 24.8 0.0 5.1e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Argonaute linker 1 domain GAGE PF05831.11 KFP07794.1 - 4.1e-05 24.1 5.2 9.4e-05 22.9 5.2 1.7 1 0 0 1 1 1 1 GAGE protein Calici_coat PF00915.20 KFP07794.1 - 0.081 11.8 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Calicivirus coat protein Frizzled PF01534.17 KFP07795.1 - 3.5e-139 463.4 23.0 4.5e-139 463.0 23.0 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 KFP07795.1 - 1.2e-33 116.0 6.9 3.2e-33 114.6 6.9 1.8 1 0 0 1 1 1 1 Fz domain MEF2_binding PF09047.10 KFP07796.1 - 1.6e-22 79.0 7.1 3.9e-22 77.8 7.1 1.7 1 0 0 1 1 1 1 MEF2 binding TPR_2 PF07719.17 KFP07796.1 - 2.9e-08 33.2 24.3 0.26 11.5 0.1 8.2 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 KFP07796.1 - 3.2e-05 23.6 25.5 0.071 13.0 0.1 8.2 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFP07796.1 - 0.00021 20.9 4.5 0.028 14.1 0.0 4.6 5 0 0 5 5 5 1 TPR repeat TPR_17 PF13431.6 KFP07796.1 - 0.0015 18.8 15.5 4.6 7.9 0.0 7.5 10 0 0 10 10 6 2 Tetratricopeptide repeat FAT PF02259.23 KFP07796.1 - 0.003 16.8 0.1 0.029 13.6 0.0 2.5 2 0 0 2 2 2 1 FAT domain TPR_8 PF13181.6 KFP07796.1 - 0.017 15.3 25.1 0.47 10.8 0.1 8.0 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFP07796.1 - 0.029 14.5 0.5 0.43 10.7 0.5 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFP07796.1 - 0.047 14.0 10.7 9.4 6.6 0.3 5.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFP07796.1 - 0.12 13.0 8.7 45 4.8 0.0 5.6 5 1 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP07796.1 - 0.25 11.4 3.6 4.8 7.5 0.1 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFP07796.1 - 0.47 11.2 2.1 28 5.7 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFP07796.1 - 2.8 9.0 9.8 27 5.9 0.3 6.2 6 1 1 7 7 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP07796.1 - 8.6 6.7 17.9 7.4 6.9 0.1 6.3 6 1 0 7 7 6 0 Anaphase-promoting complex, cyclosome, subunit 3 T-box PF00907.22 KFP07797.1 - 6.8e-81 270.9 0.2 9.6e-81 270.4 0.2 1.2 1 0 0 1 1 1 1 T-box SH3_2 PF07653.17 KFP07798.1 - 2.4e-24 84.8 0.2 9.2e-13 47.7 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KFP07798.1 - 2.6e-21 75.0 0.3 4.2e-16 58.3 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH2 PF00017.24 KFP07798.1 - 3.8e-21 75.0 0.0 6.7e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 KFP07798.1 - 2.6e-15 56.0 0.1 1.1e-07 31.6 0.1 2.8 3 0 0 3 3 3 2 Variant SH3 domain hSH3 PF14603.6 KFP07798.1 - 0.01 16.2 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 Helically-extended SH3 domain mit_SMPDase PF14724.6 KFP07799.1 - 0 1506.0 5.2 0 1505.8 5.2 1.0 1 0 0 1 1 1 1 Mitochondrial-associated sphingomyelin phosphodiesterase G_glu_transpept PF01019.21 KFP07800.1 - 2.2e-177 590.9 0.0 2.5e-177 590.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase LSM PF01423.22 KFP07801.1 - 6.9e-16 57.7 0.2 9.5e-16 57.3 0.2 1.2 1 0 0 1 1 1 1 LSM domain Kringle PF00051.18 KFP07801.1 - 0.15 12.4 0.1 0.23 11.8 0.1 1.3 1 0 0 1 1 1 0 Kringle domain Guanylate_cyc_2 PF09778.9 KFP07802.1 - 6.5e-94 313.2 4.0 7.3e-94 313.0 4.0 1.0 1 0 0 1 1 1 1 Guanylylate cyclase Peptidase_C39_2 PF13529.6 KFP07802.1 - 1.8e-09 38.3 0.1 6.4e-09 36.5 0.1 1.9 1 1 0 1 1 1 1 Peptidase_C39 like family Peptidase_C70 PF12385.8 KFP07802.1 - 5.8e-07 29.6 0.0 0.027 14.4 0.0 2.4 2 1 0 2 2 2 2 Papain-like cysteine protease AvrRpt2 DUF3335 PF11814.8 KFP07802.1 - 2.1e-05 24.1 0.3 0.014 14.8 0.1 2.2 2 0 0 2 2 2 2 Peptidase_C39 like family Peptidase_C39 PF03412.15 KFP07802.1 - 0.00035 20.4 0.1 0.0065 16.3 0.1 2.5 2 1 0 2 2 2 1 Peptidase C39 family PyocinActivator PF11112.8 KFP07802.1 - 0.13 12.4 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Pyocin activator protein PrtN TMEM52 PF14979.6 KFP07802.1 - 0.24 11.3 5.7 0.47 10.4 5.7 1.5 1 0 0 1 1 1 0 Transmembrane 52 CN_hydrolase PF00795.22 KFP07803.1 - 2e-62 210.9 0.0 2.5e-62 210.6 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase 7tm_1 PF00001.21 KFP07804.1 - 1.2e-46 159.2 16.3 1.4e-46 159.0 16.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP07804.1 - 3.5e-08 33.5 9.8 4.7e-08 33.1 9.8 1.2 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KFP07804.1 - 1.1e-07 31.5 20.4 1.6e-06 27.7 20.4 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP07804.1 - 9e-07 28.8 15.6 9e-07 28.8 15.6 2.3 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx CH PF00307.31 KFP07805.1 - 1.1e-20 73.8 0.3 5.3e-20 71.6 0.0 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFP07805.1 - 9.9e-05 22.1 0.0 0.00023 20.9 0.0 1.7 1 0 0 1 1 1 1 CAMSAP CH domain TMF_DNA_bd PF12329.8 KFP07805.1 - 0.013 15.5 1.8 0.013 15.5 1.8 9.9 8 3 3 11 11 11 0 TATA element modulatory factor 1 DNA binding RhoGAP PF00620.27 KFP07806.1 - 7.6e-50 168.7 0.2 1.6e-48 164.4 0.0 2.6 2 0 0 2 2 2 1 RhoGAP domain Bcr-Abl_Oligo PF09036.10 KFP07806.1 - 4.2e-37 126.0 4.8 4.6e-37 125.9 1.0 2.7 2 0 0 2 2 2 1 Bcr-Abl oncoprotein oligomerisation domain RhoGEF PF00621.20 KFP07806.1 - 2.2e-34 119.3 0.9 4.9e-34 118.1 0.9 1.6 1 0 0 1 1 1 1 RhoGEF domain C2 PF00168.30 KFP07806.1 - 3.2e-07 30.6 0.0 9.9e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 C2 domain PH PF00169.29 KFP07806.1 - 0.0053 17.2 3.0 0.015 15.8 0.7 2.8 2 1 0 2 2 2 1 PH domain IQ_SEC7_PH PF16453.5 KFP07806.1 - 0.021 14.8 0.0 0.065 13.2 0.0 1.8 1 0 0 1 1 1 0 PH domain Ras PF00071.22 KFP07807.1 - 1.7e-44 151.3 0.1 2.2e-44 150.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP07807.1 - 5.3e-30 104.1 0.0 8.7e-30 103.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP07807.1 - 2.8e-15 56.2 0.0 3.6e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP07807.1 - 7.4e-07 29.3 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFP07807.1 - 5.4e-05 22.6 0.0 6.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFP07807.1 - 0.00079 19.0 0.0 0.025 14.1 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KFP07807.1 - 0.013 15.0 0.0 0.19 11.3 0.0 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 KFP07807.1 - 0.017 14.5 0.0 0.038 13.4 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein RsgA_GTPase PF03193.16 KFP07807.1 - 0.043 13.7 0.0 3 7.7 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase HEAT_2 PF13646.6 KFP07808.1 - 3.6e-14 52.9 7.1 2.8e-06 27.6 0.5 4.1 1 1 3 4 4 4 3 HEAT repeats Adaptin_N PF01602.20 KFP07808.1 - 1.6e-10 40.2 5.2 3.7e-08 32.4 0.9 2.3 1 1 1 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 KFP07808.1 - 4.8e-10 39.7 1.2 0.0021 18.1 0.2 3.9 2 2 1 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFP07808.1 - 6.2e-09 35.4 5.5 0.61 10.5 0.0 6.3 7 0 0 7 7 7 3 HEAT repeat Arm PF00514.23 KFP07808.1 - 2e-08 34.0 14.6 0.0015 18.5 0.0 6.9 7 1 2 9 9 9 2 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KFP07808.1 - 0.00018 21.6 0.9 0.14 12.3 0.1 2.6 2 0 0 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KFP07808.1 - 0.00021 20.9 3.9 0.81 9.2 0.0 4.6 1 1 4 5 5 5 1 CLASP N terminal HEAT_EZ PF13513.6 KFP07808.1 - 0.0011 19.4 8.1 0.011 16.2 0.2 4.7 5 1 1 6 6 6 1 HEAT-like repeat MMS19_N PF14500.6 KFP07808.1 - 0.0016 18.1 4.3 0.35 10.4 0.2 3.6 3 1 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS22L_C PF14911.6 KFP07808.1 - 0.016 14.3 0.0 0.041 13.0 0.0 1.6 1 1 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal DUF3636 PF12331.8 KFP07808.1 - 0.11 12.3 1.2 4.1 7.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3636) RICTOR_N PF14664.6 KFP07808.1 - 0.19 10.7 2.0 3.2 6.6 0.2 2.7 2 1 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term RIX1 PF08167.12 KFP07808.1 - 0.2 11.3 2.9 1.9 8.2 0.1 2.9 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis IFRD PF05004.13 KFP07808.1 - 0.31 10.1 4.8 0.38 9.8 1.0 2.7 2 1 1 3 3 3 0 Interferon-related developmental regulator (IFRD) G-alpha PF00503.20 KFP07809.1 - 6e-118 394.0 1.5 7e-118 393.8 1.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFP07809.1 - 1.1e-16 60.8 0.3 7.6e-11 41.8 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFP07809.1 - 0.00024 20.5 4.6 0.016 14.5 0.5 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP07809.1 - 0.0032 17.6 0.3 1.2 9.2 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase TniB PF05621.11 KFP07809.1 - 0.012 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Roc PF08477.13 KFP07809.1 - 0.013 15.7 1.4 1.8 8.8 0.2 2.6 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KFP07809.1 - 0.014 15.2 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2951 PF11166.8 KFP07809.1 - 0.11 12.7 0.4 14 5.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) AAA_16 PF13191.6 KFP07809.1 - 0.13 12.7 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain APG5 PF04106.12 KFP07809.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg5 SSF PF00474.17 KFP07810.1 - 5.9e-167 555.6 24.9 9.9e-167 554.9 24.9 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family TadF PF16964.5 KFP07810.1 - 0.36 10.5 0.9 0.54 10.0 0.0 1.7 2 0 0 2 2 2 0 Putative tight adherence pilin protein F 14-3-3 PF00244.20 KFP07811.1 - 3.3e-93 311.3 6.7 3.7e-93 311.1 6.7 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF3504 PF12012.8 KFP07811.1 - 0.08 12.9 0.4 0.14 12.0 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) SIX1_SD PF16878.5 KFP07812.1 - 2.7e-14 53.6 0.6 2.7e-14 53.6 0.6 1.6 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 KFP07812.1 - 7.8e-10 38.5 1.4 2.2e-09 37.0 1.4 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP07812.1 - 1.4e-06 28.1 0.6 1.4e-06 28.1 0.6 1.9 2 0 0 2 2 2 1 Homeobox KN domain HTH_Tnp_1 PF01527.20 KFP07812.1 - 0.072 13.4 0.1 0.18 12.2 0.1 1.7 1 1 0 1 1 1 0 Transposase CENP-B_N PF04218.13 KFP07812.1 - 0.11 12.1 0.1 0.4 10.4 0.0 1.9 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain IML1 PF12257.8 KFP07813.1 - 5.7e-114 380.0 0.4 9.3e-114 379.4 0.4 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KFP07813.1 - 6.7e-10 38.9 0.0 1.6e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FGGY_N PF00370.21 KFP07813.1 - 0.091 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Tantalus PF15386.6 KFP07814.1 - 3.2e-25 88.0 2.7 7.1e-25 86.9 2.7 1.6 1 0 0 1 1 1 1 Drosophila Tantalus-like Transferrin PF00405.17 KFP07815.1 - 1.1e-142 475.1 2.9 2.2e-74 250.6 0.2 2.2 2 1 0 2 2 2 2 Transferrin Phosphonate-bd PF12974.7 KFP07815.1 - 9.3e-07 28.7 0.0 0.061 12.9 0.0 2.9 3 0 0 3 3 3 2 ABC transporter, phosphonate, periplasmic substrate-binding protein PS_Dcarbxylase PF02666.15 KFP07816.1 - 1.3e-68 230.5 0.0 1.7e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase MMR_HSR1_Xtn PF16897.5 KFP07817.1 - 1.1e-45 154.0 0.4 1.9e-45 153.2 0.4 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KFP07817.1 - 6.4e-25 87.0 0.1 1.5e-24 85.8 0.1 1.7 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KFP07817.1 - 1.6e-19 70.1 0.0 3.5e-19 69.0 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFP07817.1 - 8.1e-11 41.7 0.1 1.1e-09 38.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 KFP07817.1 - 0.0029 16.6 0.4 0.021 13.8 0.1 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 KFP07817.1 - 0.004 17.2 0.3 2.4 8.2 0.2 2.3 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 KFP07817.1 - 0.0044 16.6 0.1 3.8 7.0 0.0 3.7 2 2 1 3 3 3 1 Elongation factor Tu GTP binding domain DUF1890 PF09001.11 KFP07817.1 - 0.15 12.5 0.3 0.3 11.5 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1890) zf-C2H2_4 PF13894.6 KFP07818.1 - 5.8e-31 104.5 48.4 0.00018 22.1 1.9 8.6 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP07818.1 - 1e-28 98.1 51.2 0.0001 22.5 0.8 8.5 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_assoc3 PF16637.5 KFP07818.1 - 1.1e-28 99.2 3.9 1.1e-28 99.2 3.9 2.6 4 0 0 4 4 2 1 Putative zinc-finger between two C2H2 zinc-fingers on Patz zf-C2H2_jaz PF12171.8 KFP07818.1 - 2.3e-15 56.4 25.5 0.0015 18.8 0.6 8.2 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KFP07818.1 - 8.8e-15 54.4 58.4 3e-06 27.4 2.2 10.2 11 0 0 11 11 10 4 Zinc-finger double domain zf-met PF12874.7 KFP07818.1 - 1.2e-12 47.7 27.1 0.027 14.8 0.6 8.1 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFP07818.1 - 1.6e-11 43.9 45.6 1.4e-05 24.9 3.1 8.4 8 0 0 8 8 8 4 C2H2-type zinc finger zf-Di19 PF05605.12 KFP07818.1 - 3.9e-05 23.8 29.8 0.052 13.9 1.1 5.9 3 1 2 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 KFP07818.1 - 0.00036 21.2 20.2 0.013 16.1 0.9 5.5 2 2 3 5 5 5 1 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 KFP07818.1 - 0.00077 19.5 26.6 0.068 13.3 0.5 5.7 4 1 2 6 6 6 3 Zinc ribbon domain zf_UBZ PF18439.1 KFP07818.1 - 0.0057 16.2 18.5 7.3 6.3 0.1 8.0 8 0 0 8 8 8 1 Ubiquitin-Binding Zinc Finger ROS_MUCR PF05443.11 KFP07818.1 - 0.023 14.7 0.1 2.6 8.1 0.0 2.8 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein zf-C2H2_8 PF15909.5 KFP07818.1 - 0.024 14.9 16.1 0.036 14.3 4.9 3.9 3 1 1 4 4 4 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 KFP07818.1 - 0.038 14.3 27.0 35 4.8 2.5 7.3 3 1 4 7 7 7 0 C2H2 type zinc-finger (2 copies) ARS2 PF04959.13 KFP07818.1 - 0.044 14.2 0.1 0.044 14.2 0.1 4.4 4 2 1 5 5 5 0 Arsenite-resistance protein 2 zf_C2H2_13 PF18508.1 KFP07818.1 - 0.067 12.8 6.3 0.61 9.7 0.1 3.6 3 0 0 3 3 3 0 Zinc finger domain DUF629 PF04780.12 KFP07818.1 - 0.071 11.6 8.7 5.2 5.5 2.4 4.2 3 1 2 5 5 5 0 Protein of unknown function (DUF629) zf-WRNIP1_ubi PF18279.1 KFP07818.1 - 0.087 13.5 1.5 32 5.5 0.0 4.6 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain GAGA PF09237.11 KFP07818.1 - 0.5 10.2 22.1 5.1 7.0 0.5 6.2 6 1 1 7 7 7 0 GAGA factor Zn-C2H2_12 PF18112.1 KFP07818.1 - 0.57 10.7 0.1 0.57 10.7 0.1 5.4 6 0 0 6 6 6 0 Autophagy receptor zinc finger-C2H2 domain DZR PF12773.7 KFP07818.1 - 1 9.4 26.6 2.5 8.2 0.2 4.8 4 1 1 5 5 4 0 Double zinc ribbon zf-C2H2_9 PF16293.5 KFP07818.1 - 2.5 8.0 13.8 1.9 8.4 0.0 5.2 5 1 1 6 6 6 0 C2H2 type zinc-finger (1 copy) DNA_ligase_ZBD PF03119.16 KFP07818.1 - 4.1 7.5 6.8 33 4.6 0.1 3.3 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain Kringle PF00051.18 KFP07819.1 - 9.3e-08 32.3 1.3 1.8e-07 31.3 1.3 1.5 1 0 0 1 1 1 1 Kringle domain SDF PF00375.18 KFP07819.1 - 0.042 12.9 0.0 0.05 12.6 0.0 1.1 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family Pkinase_Tyr PF07714.17 KFP07820.1 - 2.7e-50 171.1 0.0 3e-49 167.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP07820.1 - 1.2e-47 162.6 0.0 1.7e-47 162.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LIM PF00412.22 KFP07820.1 - 1.6e-26 92.3 18.4 5.7e-17 61.7 4.7 2.6 2 0 0 2 2 2 2 LIM domain PDZ PF00595.24 KFP07820.1 - 2.1e-15 56.8 0.0 3.7e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Kdo PF06293.14 KFP07820.1 - 9.1e-06 25.2 0.0 1.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PDZ_6 PF17820.1 KFP07820.1 - 0.00031 20.5 0.1 0.00065 19.5 0.1 1.5 1 0 0 1 1 1 1 PDZ domain APH PF01636.23 KFP07820.1 - 0.0054 16.7 0.0 0.0098 15.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Zn_ribbon_SprT PF17283.2 KFP07820.1 - 0.22 11.5 4.7 5.3 7.0 1.6 2.9 2 0 0 2 2 2 0 SprT-like zinc ribbon domain DUF2175 PF09943.9 KFP07820.1 - 0.25 11.6 5.6 0.28 11.5 1.0 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) zf-RRN7 PF11781.8 KFP07820.1 - 8.3 6.2 13.3 0.65 9.7 0.9 2.8 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-C3HC4_3 PF13920.6 KFP07821.1 - 7.4e-11 41.7 5.4 1e-10 41.3 5.4 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP07821.1 - 1.8e-10 40.5 7.5 2.5e-10 40.0 7.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP07821.1 - 6.4e-10 39.2 9.7 8.8e-10 38.8 9.7 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP07821.1 - 3.4e-09 36.4 8.9 5.1e-09 35.8 8.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP07821.1 - 2.2e-07 30.6 6.7 3.2e-07 30.1 6.7 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFP07821.1 - 2.9e-07 30.4 6.4 3.5e-06 26.9 7.3 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP07821.1 - 6.4e-07 29.2 6.4 9.3e-07 28.7 6.4 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFP07821.1 - 9.7e-06 25.8 7.0 1.6e-05 25.1 7.0 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFP07821.1 - 8.3e-05 22.6 2.6 0.00012 22.0 2.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KFP07821.1 - 0.00049 20.2 7.5 0.00073 19.6 7.5 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 KFP07821.1 - 0.00062 19.7 2.7 0.00094 19.1 2.7 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.12 KFP07821.1 - 0.01 15.2 0.2 0.013 14.8 0.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-UDP PF14569.6 KFP07821.1 - 0.015 15.4 1.5 0.04 14.0 1.5 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 KFP07821.1 - 0.025 14.4 5.8 0.057 13.2 5.8 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KFP07821.1 - 0.16 11.6 5.5 0.25 11.0 5.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type IBR PF01485.21 KFP07821.1 - 0.28 11.4 7.4 0.8 10.0 3.3 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain DUF1272 PF06906.11 KFP07821.1 - 1.2 9.3 5.3 3 8.0 5.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_11 PF17123.5 KFP07821.1 - 3.2 7.6 9.9 0.32 10.8 5.2 1.8 2 0 0 2 2 2 0 RING-like zinc finger DUF2011 PF09428.10 KFP07822.1 - 0.018 15.3 1.2 0.19 12.0 0.4 2.2 1 1 1 2 2 2 0 Fungal protein of unknown function (DUF2011) T3SS_needle_E PF08988.10 KFP07822.1 - 0.04 14.1 0.7 0.18 12.0 0.3 2.1 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle Peptidase_A22B PF04258.13 KFP07823.1 - 2.2e-94 316.2 9.1 2.9e-94 315.8 9.1 1.1 1 0 0 1 1 1 1 Signal peptide peptidase Acyl-CoA_dh_1 PF00441.24 KFP07824.1 - 1.6e-51 174.5 6.4 2.4e-51 173.9 6.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFP07824.1 - 1.2e-38 132.2 0.4 3.9e-38 130.6 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFP07824.1 - 3e-26 91.5 0.0 5.5e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFP07824.1 - 3.9e-25 88.7 3.7 6.1e-25 88.0 3.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF743 PF05332.11 KFP07824.1 - 0.016 15.2 0.1 0.033 14.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF743) GMP_PDE_delta PF05351.11 KFP07825.1 - 7e-77 256.9 1.2 7.9e-77 256.7 1.2 1.0 1 0 0 1 1 1 1 GMP-PDE, delta subunit Malectin PF11721.8 KFP07826.1 - 5.7e-40 137.1 0.3 5.7e-40 137.1 0.3 1.4 2 0 0 2 2 2 1 Malectin domain Malectin_like PF12819.7 KFP07826.1 - 0.14 11.3 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Malectin-like domain EF-hand_1 PF00036.32 KFP07827.1 - 5.7e-31 103.7 15.3 3.6e-10 38.7 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFP07827.1 - 4.3e-26 91.2 7.3 3.2e-15 56.3 1.0 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP07827.1 - 2.1e-25 86.4 6.0 4e-09 35.7 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KFP07827.1 - 2.3e-20 71.1 11.3 3.1e-08 32.8 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KFP07827.1 - 4e-20 71.4 13.1 1.8e-12 46.9 0.5 3.7 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 KFP07827.1 - 4.4e-09 36.5 0.1 0.0039 17.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 KFP07827.1 - 1.4e-05 25.2 0.1 0.0015 18.7 0.3 2.6 2 1 0 2 2 2 1 Dockerin type I domain SPARC_Ca_bdg PF10591.9 KFP07827.1 - 2e-05 24.8 0.1 0.0049 17.2 0.0 2.2 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 KFP07827.1 - 0.00016 21.7 0.2 0.4 10.6 0.0 2.5 2 1 0 2 2 2 2 Tellurite resistance protein TerB EF-hand_4 PF12763.7 KFP07827.1 - 0.0027 17.6 1.5 0.052 13.5 0.1 2.5 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand POTRA_2 PF08479.11 KFP07827.1 - 0.0096 15.7 0.0 0.027 14.3 0.0 1.8 1 0 0 1 1 1 1 POTRA domain, ShlB-type DIMCO_N PF16844.5 KFP07827.1 - 0.0098 16.2 0.1 0.052 13.9 0.0 2.0 2 0 0 2 2 2 1 Dinitrogenase iron-molybdenum cofactor, N-terminal DUF3349 PF11829.8 KFP07827.1 - 0.018 15.8 0.0 4.8 8.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) Caleosin PF05042.13 KFP07827.1 - 0.023 14.6 0.0 1.2 9.1 0.0 2.4 2 1 0 2 2 2 0 Caleosin related protein EF-hand_11 PF08976.11 KFP07827.1 - 0.05 14.5 0.1 1.3 10.0 0.0 2.0 1 1 1 2 2 2 0 EF-hand domain DUF5580 PF17743.1 KFP07827.1 - 0.094 11.2 0.0 0.75 8.3 0.0 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5580) DUF2666 PF10869.8 KFP07827.1 - 0.098 12.9 0.1 7.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) RNase_P_Rpp14 PF01900.19 KFP07828.1 - 5e-27 94.2 0.1 7.7e-27 93.6 0.1 1.3 1 0 0 1 1 1 1 Rpp14/Pop5 family Dynein_light PF01221.18 KFP07829.1 - 3.3e-44 149.1 1.9 3.6e-44 149.0 1.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 UCH PF00443.29 KFP07829.1 - 0.11 12.0 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Ubie_methyltran PF01209.18 KFP07830.1 - 2.1e-90 302.1 0.0 2.6e-90 301.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KFP07830.1 - 5.1e-17 62.4 0.0 3.9e-15 56.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP07830.1 - 6.5e-17 62.0 0.0 1.6e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP07830.1 - 2e-14 53.6 0.0 9.6e-13 48.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP07830.1 - 1.1e-08 35.7 0.0 8.7e-08 32.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP07830.1 - 3.6e-05 23.6 0.0 5.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KFP07830.1 - 0.0067 16.3 0.0 0.025 14.4 0.0 2.0 3 0 0 3 3 3 1 Hypothetical methyltransferase UPF0020 PF01170.18 KFP07830.1 - 0.017 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Tmemb_55A PF09788.9 KFP07830.1 - 0.26 10.3 0.0 0.37 9.8 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A Dynein_light PF01221.18 KFP07831.1 - 2e-43 146.6 1.9 2.2e-43 146.5 1.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Glu-tRNAGln PF02686.15 KFP07832.1 - 9.8e-13 48.2 0.2 5.2e-12 45.9 0.1 1.9 1 1 1 2 2 2 1 Glu-tRNAGln amidotransferase C subunit UPF0203 PF05254.12 KFP07833.1 - 3.5e-25 88.0 0.4 4e-25 87.9 0.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 KFP07833.1 - 0.0069 16.7 0.5 0.016 15.5 0.5 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) CX9C PF16860.5 KFP07833.1 - 0.0073 16.3 0.7 0.49 10.5 0.1 2.1 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UCR_hinge PF02320.16 KFP07833.1 - 0.015 15.4 1.5 0.08 13.2 1.8 1.8 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein CHCH PF06747.13 KFP07833.1 - 0.053 13.7 1.8 3.7 7.8 0.1 2.3 2 0 0 2 2 2 0 CHCH domain DUF5339 PF17274.2 KFP07833.1 - 0.09 13.6 0.8 3.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5339) COX6B PF02297.17 KFP07833.1 - 0.12 12.6 2.6 0.21 11.9 2.6 1.4 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb COX6A PF02046.15 KFP07834.1 - 2.8e-15 56.8 0.0 5.6e-15 55.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIa RRM_1 PF00076.22 KFP07835.1 - 1.1e-29 102.0 1.7 2.4e-15 56.1 0.6 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP07835.1 - 7.2e-06 26.0 0.3 0.00049 20.2 0.4 2.7 2 1 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KFP07835.1 - 0.0016 18.4 0.2 0.58 10.2 0.1 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KFP07835.1 - 0.0084 16.4 0.1 0.36 11.0 0.1 2.2 1 1 1 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter NID PF07292.13 KFP07835.1 - 0.095 13.4 0.7 3.7 8.2 0.1 2.2 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) CSD PF00313.22 KFP07835.1 - 0.24 11.3 1.3 3 7.8 0.3 2.3 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain Phospholip_A2_1 PF00068.19 KFP07836.1 - 1.7e-36 125.1 14.3 2.1e-36 124.8 14.3 1.0 1 0 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.10 KFP07836.1 - 0.022 14.9 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 Parvovirus coat protein VP1 Phospholip_A2_2 PF05826.12 KFP07836.1 - 0.18 12.1 16.1 0.53 10.5 9.5 2.3 1 1 1 2 2 2 0 Phospholipase A2 SIR2 PF02146.17 KFP07837.1 - 1.9e-51 174.5 0.0 2.9e-51 173.9 0.0 1.3 1 1 0 1 1 1 1 Sir2 family zf-ACC PF17848.1 KFP07837.1 - 0.43 10.7 0.1 0.43 10.7 0.1 2.4 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain XPA_N PF01286.18 KFP07837.1 - 2.4 8.3 6.7 0.86 9.7 0.3 2.3 2 0 0 2 2 2 0 XPA protein N-terminal Ribosomal_L10 PF00466.20 KFP07838.1 - 8e-22 77.3 0.1 2.4e-21 75.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 KFP07838.1 - 1e-20 74.1 6.0 1e-20 74.1 6.0 1.8 2 0 0 2 2 2 1 60s Acidic ribosomal protein RL10P_insert PF17777.1 KFP07838.1 - 1.3e-13 50.7 0.1 3e-13 49.6 0.1 1.7 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P HEAT PF02985.22 KFP07839.1 - 1.1e-47 156.0 38.3 0.0037 17.4 0.0 25.6 28 0 0 28 28 27 9 HEAT repeat HEAT_2 PF13646.6 KFP07839.1 - 1.9e-34 117.9 45.1 2.4e-05 24.6 0.0 17.7 15 3 8 23 23 22 9 HEAT repeats HEAT_EZ PF13513.6 KFP07839.1 - 9.9e-30 102.6 50.3 0.0048 17.4 0.2 21.9 20 7 7 27 27 27 10 HEAT-like repeat CLASP_N PF12348.8 KFP07839.1 - 3e-18 66.2 3.7 0.0005 19.7 0.0 10.3 9 2 1 11 11 11 3 CLASP N terminal Vac14_Fab1_bd PF12755.7 KFP07839.1 - 9.8e-16 58.1 0.0 0.41 11.3 0.0 10.0 10 1 1 11 11 11 4 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KFP07839.1 - 1.1e-15 58.0 16.3 0.096 12.7 0.0 11.3 10 2 0 11 11 11 5 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 KFP07839.1 - 9.7e-11 41.5 6.1 0.03 14.2 0.0 9.6 10 1 0 10 10 10 2 UME (NUC010) domain MMS19_C PF12460.8 KFP07839.1 - 1.1e-06 28.0 14.9 0.031 13.4 0.0 7.1 7 1 0 7 7 7 3 RNAPII transcription regulator C-terminal ParcG PF10274.9 KFP07839.1 - 4.2e-06 27.0 7.3 2.8 8.0 0.0 7.8 9 0 0 9 9 9 2 Parkin co-regulated protein DUF3385 PF11865.8 KFP07839.1 - 5.6e-05 23.1 2.1 17 5.2 0.0 7.5 7 0 0 7 7 7 0 Domain of unknown function (DUF3385) Condensin2nSMC PF12422.8 KFP07839.1 - 0.028 14.6 0.9 26 5.0 0.0 5.1 6 0 0 6 6 6 0 Condensin II non structural maintenance of chromosomes subunit RICTOR_M PF14666.6 KFP07839.1 - 0.047 13.5 6.2 4.7 7.0 0.1 5.8 6 0 0 6 6 6 0 Rapamycin-insensitive companion of mTOR, middle domain Arm PF00514.23 KFP07839.1 - 3.2 7.9 17.0 60 3.9 0.1 8.5 10 0 0 10 10 9 0 Armadillo/beta-catenin-like repeat Ras PF00071.22 KFP07840.1 - 4.5e-55 185.7 0.5 6.1e-55 185.2 0.5 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP07840.1 - 2.5e-31 108.4 1.9 2.8e-31 108.2 0.2 1.9 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP07840.1 - 9.4e-16 57.8 0.2 1.3e-15 57.3 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP07840.1 - 1.2e-06 28.3 0.4 2e-06 27.5 0.3 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFP07840.1 - 0.0011 19.0 0.3 0.0019 18.2 0.3 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dioxygenase_N PF04444.14 KFP07840.1 - 0.091 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Catechol dioxygenase N terminus Glycoprot_B_PH2 PF17417.2 KFP07840.1 - 0.43 10.9 3.9 2 8.8 0.9 2.3 2 1 0 2 2 2 0 Herpesvirus Glycoprotein B PH-like domain ATG16 PF08614.11 KFP07841.1 - 0.005 17.1 27.4 0.005 17.1 27.4 4.0 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) GP57 PF17594.2 KFP07841.1 - 0.18 11.5 5.8 0.12 12.1 0.4 3.2 4 0 0 4 4 4 0 Phage Tail fiber assembly helper gene product 57 CENP-F_leu_zip PF10473.9 KFP07841.1 - 0.41 10.7 74.6 1.1 9.3 18.3 5.3 1 1 4 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2277 PF10041.9 KFP07841.1 - 7.3 7.0 7.1 12 6.3 0.2 3.3 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2277) Pkinase PF00069.25 KFP07842.1 - 1.6e-61 208.0 2.7 1.9e-60 204.5 0.0 3.4 2 1 0 2 2 2 1 Protein kinase domain CNH PF00780.22 KFP07842.1 - 1.9e-60 204.8 0.0 4.2e-60 203.7 0.0 1.5 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.17 KFP07842.1 - 4.5e-29 101.5 0.0 1.3e-28 100.0 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KFP07842.1 - 6.2e-10 39.5 0.0 2.4e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 PH domain C1_1 PF00130.22 KFP07842.1 - 2.6e-05 24.0 9.2 5.4e-05 23.0 9.2 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Seadorna_VP7 PF07387.11 KFP07842.1 - 0.00092 18.4 0.0 0.003 16.7 0.0 1.9 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_C PF00433.24 KFP07842.1 - 0.0026 18.4 1.6 0.0082 16.8 1.6 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 KFP07842.1 - 0.0077 16.2 0.1 0.0077 16.2 0.1 4.9 4 3 1 5 5 5 1 Phosphotransferase enzyme family AMPK1_CBM PF16561.5 KFP07843.1 - 2.6e-35 120.5 0.3 4.7e-35 119.7 0.3 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KFP07843.1 - 8.6e-28 96.4 1.8 1.5e-27 95.7 1.8 1.4 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 KFP07843.1 - 0.0072 16.7 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CD225 PF04505.12 KFP07844.1 - 1.8e-18 66.5 0.7 2.3e-18 66.1 0.7 1.1 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF4190 PF13828.6 KFP07844.1 - 0.0043 16.8 4.3 0.02 14.7 4.3 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4190) Claudin_3 PF06653.11 KFP07844.1 - 0.018 15.0 1.1 0.022 14.7 1.1 1.1 1 0 0 1 1 1 0 Tight junction protein, Claudin-like DUF5493 PF17597.2 KFP07844.1 - 0.085 13.1 1.4 0.12 12.7 1.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5493) DUF4698 PF15769.5 KFP07845.1 - 3.1e-146 488.3 10.9 3.5e-146 488.1 10.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4698) RVT_1 PF00078.27 KFP07846.1 - 0.072 12.6 0.0 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Homeodomain PF00046.29 KFP07847.1 - 9.8e-23 79.8 8.4 2e-22 78.8 8.4 1.6 1 0 0 1 1 1 1 Homeodomain DUF2209 PF09974.9 KFP07847.1 - 0.02 15.2 0.1 0.03 14.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Homeobox_KN PF05920.11 KFP07847.1 - 0.13 12.2 0.3 0.13 12.2 0.3 2.0 2 0 0 2 2 2 0 Homeobox KN domain Homeodomain PF00046.29 KFP07848.1 - 2.4e-21 75.3 8.2 4.6e-21 74.4 8.2 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP07848.1 - 0.4 10.6 2.9 0.49 10.3 1.5 1.9 2 0 0 2 2 2 0 Homeobox KN domain Hox9_act PF04617.13 KFP07849.1 - 1.6e-59 201.8 1.2 1.6e-59 201.8 1.2 1.5 2 0 0 2 2 2 1 Hox9 activation region Homeodomain PF00046.29 KFP07849.1 - 8e-21 73.7 6.4 1.3e-20 73.0 6.4 1.4 1 0 0 1 1 1 1 Homeodomain HTH_23 PF13384.6 KFP07849.1 - 0.051 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain CI-B14_5a PF07347.12 KFP07849.1 - 0.063 13.2 0.2 0.18 11.7 0.2 1.7 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Homeodomain PF00046.29 KFP07850.1 - 4.6e-21 74.4 6.0 1.3e-20 72.9 6.0 1.9 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP07850.1 - 0.029 14.3 2.6 0.042 13.8 0.4 2.4 2 0 0 2 2 2 0 Homeobox KN domain Cor1 PF04803.12 KFP07850.1 - 0.03 14.6 4.3 0.045 13.9 4.3 1.2 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region Mito_fiss_reg PF05308.11 KFP07850.1 - 0.37 10.8 12.1 0.94 9.5 12.1 1.7 1 0 0 1 1 1 0 Mitochondrial fission regulator Zip PF02535.22 KFP07850.1 - 0.54 9.4 1.1 0.73 9.0 1.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3528 PF12045.8 KFP07851.1 - 4e-60 202.5 2.3 6.4e-60 201.9 2.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3528) Homeodomain PF00046.29 KFP07851.1 - 1.6e-19 69.5 8.3 3.2e-19 68.5 8.3 1.5 1 0 0 1 1 1 1 Homeodomain Baculo_p74_N PF08404.10 KFP07851.1 - 0.014 14.6 0.1 0.019 14.1 0.1 1.2 1 0 0 1 1 1 0 Baculoviridae P74 N-terminal Homeobox_KN PF05920.11 KFP07851.1 - 0.029 14.3 0.7 0.073 13.0 0.7 1.7 1 0 0 1 1 1 0 Homeobox KN domain Homeodomain PF00046.29 KFP07852.1 - 4.6e-20 71.2 7.0 5e-20 71.1 7.0 1.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP07852.1 - 0.00069 19.5 1.4 0.0011 18.8 1.4 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 KFP07852.1 - 0.0056 16.1 0.2 0.0073 15.7 0.2 1.2 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeodomain PF00046.29 KFP07854.1 - 2.5e-19 68.9 7.6 3e-19 68.6 7.6 1.1 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP07854.1 - 2.1e-05 24.3 2.1 3.9e-05 23.4 2.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain DUF1510 PF07423.11 KFP07854.1 - 0.028 14.6 0.0 0.03 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1510) Homez PF11569.8 KFP07854.1 - 0.052 13.0 0.1 0.071 12.6 0.1 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez bZIP_1 PF00170.21 KFP07857.1 - 4.8e-13 49.0 7.6 8.6e-13 48.2 7.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFP07857.1 - 2.3e-09 37.2 7.9 5.3e-09 36.0 7.9 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFP07857.1 - 0.00015 22.2 7.0 0.00028 21.4 7.0 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Cnn_1N PF07989.11 KFP07857.1 - 0.024 14.8 1.7 0.041 14.0 1.7 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 NDUFB11 PF17250.2 KFP07857.1 - 0.19 12.4 0.4 0.34 11.6 0.4 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase 11 kDa subunit GIT_CC PF16559.5 KFP07857.1 - 0.25 11.2 3.0 0.47 10.3 3.0 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor dsrm PF00035.26 KFP07858.1 - 5.4e-21 75.1 0.0 1e-13 51.8 0.0 2.1 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KFP07858.1 - 3.9e-08 33.4 0.3 0.00022 21.4 0.3 2.8 2 1 0 2 2 2 2 double strand RNA binding domain from DEAD END PROTEIN 1 Pkinase PF00069.25 KFP07859.1 - 1.3e-51 175.5 0.0 1.5e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP07859.1 - 3.7e-49 167.3 0.0 4.6e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP07859.1 - 0.0021 16.9 0.0 0.0029 16.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP07859.1 - 0.073 13.0 0.0 0.26 11.2 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KFP07859.1 - 0.12 12.0 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family KH_1 PF00013.29 KFP07860.1 - 7.6e-24 83.3 7.7 1.2e-15 57.1 0.8 3.1 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KFP07860.1 - 0.022 14.6 2.1 0.027 14.3 0.8 1.7 2 0 0 2 2 2 0 KH domain MOEP19 PF16005.5 KFP07860.1 - 0.067 13.2 0.0 0.48 10.5 0.0 2.1 2 0 0 2 2 2 0 KH-like RNA-binding domain PFK PF00365.20 KFP07861.1 - 3.1e-15 56.3 0.0 3.8e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Phosphofructokinase Lectin_leg-like PF03388.13 KFP07862.1 - 2e-78 262.9 0.0 2.6e-78 262.5 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 KFP07862.1 - 1.1e-09 38.6 0.2 1.9e-09 37.8 0.2 1.3 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 KFP07862.1 - 0.0036 16.9 0.0 0.0081 15.7 0.0 1.7 1 1 0 1 1 1 1 Legume lectin domain ApoLp-III PF07464.11 KFP07862.1 - 0.018 15.2 6.3 0.14 12.3 0.6 2.5 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) AhpC-TSA_2 PF13911.6 KFP07862.1 - 0.048 13.8 0.3 2.3 8.4 0.0 2.3 2 0 0 2 2 2 0 AhpC/TSA antioxidant enzyme CorA PF01544.18 KFP07862.1 - 0.08 12.2 2.0 0.18 11.1 2.0 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein SHE3 PF17078.5 KFP07862.1 - 0.2 11.3 5.0 3.6 7.2 0.1 2.3 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 AAA_32 PF13654.6 KFP07862.1 - 0.37 9.5 10.8 1.1 7.9 5.8 2.1 1 1 1 2 2 2 0 AAA domain V-SNARE PF05008.15 KFP07862.1 - 0.39 11.1 3.8 0.37 11.2 1.2 2.3 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF4404 PF14357.6 KFP07862.1 - 0.67 10.6 7.1 8 7.2 0.7 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) PIN_8 PF18476.1 KFP07862.1 - 0.73 9.7 5.3 1.4 8.8 1.1 2.3 1 1 0 2 2 2 0 PIN like domain GCN5L1 PF06320.13 KFP07862.1 - 0.85 9.8 4.1 0.78 9.9 0.7 2.4 2 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Mis14 PF08641.12 KFP07862.1 - 0.94 9.8 5.5 1 9.7 0.8 2.4 2 1 1 3 3 3 0 Kinetochore protein Mis14 like DASH_Dad1 PF08649.10 KFP07862.1 - 1.5 9.1 4.7 0.82 9.9 0.7 2.4 3 0 0 3 3 3 0 DASH complex subunit Dad1 DUF148 PF02520.17 KFP07862.1 - 1.6 8.8 6.1 1 9.5 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function DUF148 DUF3086 PF11285.8 KFP07862.1 - 1.9 7.5 7.6 0.5 9.4 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) Golgin_A5 PF09787.9 KFP07862.1 - 2.1 7.7 10.9 4.8 6.6 10.9 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 5 OmpH PF03938.14 KFP07862.1 - 2.2 8.6 12.5 0.14 12.5 7.0 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Synaphin PF05835.12 KFP07863.1 - 2.9e-48 163.7 10.3 3.9e-48 163.3 10.3 1.2 1 0 0 1 1 1 1 Synaphin protein VIT1 PF01988.19 KFP07863.1 - 3.7 7.4 4.4 5.9 6.7 4.5 1.4 1 1 0 1 1 1 0 VIT family Peptidase_S24 PF00717.23 KFP07864.1 - 3.5e-11 42.9 0.1 4.9e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase S24-like zf-C2H2 PF00096.26 KFP07865.1 - 1.7e-18 65.9 111.9 0.0025 18.2 0.5 15.2 15 0 0 15 15 15 12 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KFP07865.1 - 2.2e-16 59.3 3.8 2.2e-16 59.3 3.8 10.1 12 0 0 12 12 12 5 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KFP07865.1 - 2.6e-15 55.8 97.6 0.0032 18.2 0.3 14.6 14 0 0 14 14 14 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP07865.1 - 9e-07 29.0 0.4 0.00028 21.1 0.1 9.4 12 0 0 12 12 12 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP07865.1 - 5e-06 26.4 0.1 5e-06 26.4 0.1 10.1 11 0 0 11 11 11 2 C2H2-type zinc finger zf-met PF12874.7 KFP07865.1 - 0.00099 19.4 3.2 0.019 15.4 0.3 11.4 13 0 0 13 13 13 5 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KFP07865.1 - 2.5 8.7 81.3 0.048 14.1 1.1 14.2 16 1 0 16 16 16 0 Zinc-finger double domain Peptidase_C14 PF00656.22 KFP07866.1 - 1.2e-21 77.8 0.0 2.1e-20 73.8 0.0 1.9 1 1 0 1 1 1 1 Caspase domain Trehalose_PPase PF02358.16 KFP07866.1 - 0.073 12.2 0.0 0.37 9.9 0.0 2.0 2 0 0 2 2 2 0 Trehalose-phosphatase CIF PF16374.5 KFP07866.1 - 0.092 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Cycle inhibiting factor (CIF) Alpha_kinase PF02816.18 KFP07867.1 - 8.2e-35 120.6 0.0 1.3e-34 120.0 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family Tsg PF04668.12 KFP07867.1 - 0.0048 17.6 0.5 0.0094 16.6 0.2 1.5 1 1 0 1 1 1 1 Twisted gastrulation (Tsg) protein conserved region Ehrlichia_rpt PF09528.10 KFP07867.1 - 0.16 11.4 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 Ehrlichia tandem repeat (Ehrlichia_rpt) zf-CCHC_3 PF13917.6 KFP07867.1 - 0.31 11.0 0.2 0.31 11.0 0.2 2.6 3 0 0 3 3 3 0 Zinc knuckle HECT PF00632.25 KFP07868.1 - 2.4e-102 342.5 0.1 3.2e-102 342.2 0.1 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KFP07868.1 - 5.6e-50 167.1 29.8 8.4e-13 48.2 0.2 5.3 5 0 0 5 5 5 4 WW domain C2 PF00168.30 KFP07868.1 - 1.3e-20 73.6 0.0 3.4e-20 72.3 0.0 1.8 1 0 0 1 1 1 1 C2 domain tRNA-synt_2 PF00152.20 KFP07869.1 - 2.6e-111 371.7 0.0 3.7e-111 371.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFP07869.1 - 1.9e-11 43.8 0.0 3.6e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1565 PF07602.11 KFP07869.1 - 0.014 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) tRNA_anti-like PF12869.7 KFP07869.1 - 0.085 12.5 0.0 0.24 11.0 0.0 1.7 1 1 0 1 1 1 0 tRNA_anti-like Ferrochelatase PF00762.19 KFP07870.1 - 2.2e-110 368.7 0.0 2.5e-110 368.5 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Homeodomain PF00046.29 KFP07871.1 - 1.5e-11 44.0 1.2 2.3e-11 43.4 1.2 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP07871.1 - 1.3e-05 25.0 0.4 2.9e-05 23.9 0.1 1.7 2 0 0 2 2 2 1 Homeobox KN domain HOCHOB PF17943.1 KFP07871.1 - 0.032 14.9 0.1 0.049 14.3 0.1 1.2 1 0 0 1 1 1 0 Homeobox-cysteine loop-homeobox PH_3 PF14593.6 KFP07871.1 - 0.048 13.8 0.6 0.059 13.5 0.6 1.1 1 0 0 1 1 1 0 PH domain WD40 PF00400.32 KFP07872.1 - 1.1e-19 70.3 19.5 0.00013 22.7 0.1 7.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP07872.1 - 4.3e-09 36.6 0.0 0.061 13.6 0.0 6.8 4 3 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP07872.1 - 0.089 11.4 1.9 7.4 5.1 0.0 3.1 3 0 0 3 3 3 0 Nucleoporin Nup120/160 PITH PF06201.13 KFP07873.1 - 1.5e-40 138.9 0.0 2.1e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 KFP07873.1 - 1.2e-14 54.2 0.0 1.9e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KFP07873.1 - 0.0015 17.9 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Sad1_UNC PF07738.13 KFP07873.1 - 0.024 14.6 0.0 0.053 13.5 0.0 1.6 1 1 0 1 1 1 0 Sad1 / UNC-like C-terminal Ras PF00071.22 KFP07875.1 - 5.5e-55 185.4 0.0 7e-55 185.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP07875.1 - 2.3e-32 111.7 0.0 3.5e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP07875.1 - 1.5e-13 50.6 0.0 2.3e-13 50.0 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFP07875.1 - 9.5e-05 22.4 0.1 0.096 12.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFP07875.1 - 0.0004 20.4 0.0 0.00085 19.4 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.6 KFP07875.1 - 0.00064 19.5 0.1 0.059 13.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 KFP07875.1 - 0.0064 16.1 0.0 0.017 14.6 0.0 1.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KFP07875.1 - 0.01 15.6 0.5 0.17 11.6 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein CENP-M PF11111.8 KFP07875.1 - 0.027 13.6 0.0 0.038 13.2 0.0 1.1 1 0 0 1 1 1 0 Centromere protein M (CENP-M) G-alpha PF00503.20 KFP07875.1 - 0.035 13.3 0.4 5.9 5.9 0.1 2.3 1 1 1 2 2 2 0 G-protein alpha subunit Gtr1_RagA PF04670.12 KFP07875.1 - 0.059 12.7 0.1 0.15 11.4 0.1 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KFP07875.1 - 0.13 12.6 0.0 0.21 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain RVT_1 PF00078.27 KFP07876.1 - 0.065 12.7 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ion_trans PF00520.31 KFP07877.1 - 6.2e-21 74.7 15.8 9.5e-21 74.1 15.8 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KFP07877.1 - 4.4e-18 65.1 0.0 9.5e-18 64.1 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KFP07877.1 - 0.017 15.1 0.4 0.017 15.1 0.4 2.1 2 0 0 2 2 2 0 Ion channel DUF1759 PF03564.15 KFP07877.1 - 0.08 12.9 1.4 1.1 9.1 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1759) PDCD9 PF07147.12 KFP07878.1 - 6e-118 394.9 0.0 7.2e-118 394.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) FGF PF00167.18 KFP07879.1 - 2.7e-47 160.0 4.8 3.4e-47 159.7 4.8 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.13 KFP07879.1 - 0.0002 21.5 0.1 0.00041 20.5 0.1 1.6 1 1 0 1 1 1 1 Fascin domain SR-25 PF10500.9 KFP07879.1 - 0.0032 17.1 1.2 0.0032 17.1 1.2 1.6 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein TraW_N PF12477.8 KFP07879.1 - 0.21 11.6 0.1 0.42 10.6 0.1 1.4 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal PNTB PF02233.16 KFP07880.1 - 1.1e-182 608.1 28.3 1.3e-182 607.9 16.8 2.3 2 0 0 2 2 2 2 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KFP07880.1 - 8.8e-71 237.6 0.5 2.1e-70 236.4 0.5 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KFP07880.1 - 1.7e-45 154.7 0.3 8.1e-45 152.5 0.1 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KFP07880.1 - 2.8e-32 111.0 2.8 2.8e-32 111.0 2.8 5.1 4 1 1 5 5 5 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 KFP07880.1 - 0.0097 15.3 0.9 0.52 9.6 0.2 2.7 2 1 1 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.22 KFP07880.1 - 0.046 13.5 1.2 11 5.8 0.0 3.1 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain ADH_zinc_N PF00107.26 KFP07880.1 - 0.22 11.5 5.9 0.31 11.0 0.3 3.8 6 0 0 6 6 6 0 Zinc-binding dehydrogenase MIF4G PF02854.19 KFP07881.1 - 5e-28 98.2 0.1 6.7e-28 97.8 0.1 1.1 1 0 0 1 1 1 1 MIF4G domain PAM2 PF07145.15 KFP07881.1 - 0.0017 17.9 0.0 0.0041 16.7 0.0 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region YdjM PF04307.14 KFP07882.1 - 0.0032 16.8 11.5 0.0077 15.6 11.0 1.7 1 1 1 2 2 2 1 LexA-binding, inner membrane-associated putative hydrolase HMG_CoA_synt_C PF08540.10 KFP07883.1 - 8.8e-127 422.5 0.4 1.1e-126 422.1 0.4 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFP07883.1 - 1.3e-108 360.6 0.5 1.8e-108 360.1 0.5 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.10 KFP07883.1 - 0.0035 17.1 0.1 0.0082 16.0 0.1 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Phage_holin_7_1 PF16081.5 KFP07883.1 - 0.15 12.3 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Cullin PF00888.22 KFP07883.1 - 0.16 10.5 0.1 0.24 9.9 0.1 1.1 1 0 0 1 1 1 0 Cullin family Pkinase PF00069.25 KFP07884.1 - 7e-70 235.4 0.1 1e-69 234.9 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP07884.1 - 2e-39 135.4 0.0 2.8e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP07884.1 - 8e-09 35.2 0.0 1.2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFP07884.1 - 0.00042 20.0 0.1 0.00065 19.3 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KFP07884.1 - 0.0014 18.0 0.1 0.0023 17.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family IFN-gamma PF00714.17 KFP07884.1 - 0.024 14.5 2.0 0.22 11.4 0.1 2.5 1 1 1 2 2 2 0 Interferon gamma BTB PF00651.31 KFP07885.1 - 1.1e-24 86.7 1.1 2.4e-24 85.7 0.5 2.0 2 0 0 2 2 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFP07885.1 - 1.3e-14 53.8 52.7 2.7e-07 30.7 6.2 7.5 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFP07885.1 - 8.7e-11 41.7 53.2 0.017 15.6 0.2 6.6 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP07885.1 - 9.2e-11 41.6 61.0 0.022 15.6 0.3 7.1 7 0 0 7 7 6 6 C2H2-type zinc finger zf-met PF12874.7 KFP07885.1 - 1.2e-06 28.7 36.5 0.00028 21.2 0.9 6.5 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFP07885.1 - 0.00012 22.0 46.2 0.0083 16.1 1.8 6.7 6 1 0 6 6 6 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP07885.1 - 0.0064 16.7 0.4 0.0064 16.7 0.4 6.7 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFP07885.1 - 0.0085 15.9 2.0 1.3 8.9 0.0 3.7 3 0 0 3 3 3 1 GAGA factor zinc_ribbon_15 PF17032.5 KFP07885.1 - 0.57 11.0 20.2 9.2 7.1 2.6 3.8 2 1 1 3 3 3 0 zinc-ribbon family zf-AD PF07776.15 KFP07885.1 - 1.1 9.5 16.0 0.56 10.5 0.1 4.2 5 0 0 5 5 4 0 Zinc-finger associated domain (zf-AD) Zn-ribbon_8 PF09723.10 KFP07885.1 - 1.4 9.1 25.1 5.4 7.2 4.4 4.5 3 2 1 4 4 4 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 KFP07885.1 - 3.3 8.1 37.8 4 7.8 1.7 6.7 2 2 4 6 6 6 0 C2H2 type zinc-finger (2 copies) SelP_N PF04592.14 KFP07886.1 - 5.6e-43 147.0 10.7 6.2e-43 146.9 10.7 1.0 1 0 0 1 1 1 1 Selenoprotein P, N terminal region Thioredoxin PF00085.20 KFP07886.1 - 0.098 12.7 0.2 0.12 12.3 0.2 1.2 1 0 0 1 1 1 0 Thioredoxin Zip PF02535.22 KFP07886.1 - 1.4 8.0 3.7 1.3 8.1 3.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Pox_A_type_inc PF04508.12 KFP07887.1 - 0.23 11.4 0.2 0.23 11.4 0.2 3.7 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat SYCP2_SLD PF18584.1 KFP07887.1 - 0.23 11.7 9.8 0.18 12.1 1.8 2.3 1 1 1 2 2 2 0 Synaptonemal complex 2 Spt16M-like domain OmpH PF03938.14 KFP07887.1 - 0.39 11.0 26.1 0.87 9.9 8.3 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Tropomyosin_1 PF12718.7 KFP07887.1 - 0.5 10.5 28.7 0.95 9.6 10.4 2.2 1 1 1 2 2 2 0 Tropomyosin like Gp-FAR-1 PF05823.12 KFP07887.1 - 0.68 10.3 16.9 8.1 6.8 0.2 3.1 1 1 2 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Microvir_H PF04687.12 KFP07887.1 - 0.72 9.2 2.5 1.6 8.0 1.5 1.9 1 1 0 1 1 1 0 Microvirus H protein (pilot protein) Cnn_1N PF07989.11 KFP07887.1 - 1.2 9.3 28.0 0.039 14.1 7.9 3.5 2 1 0 3 3 3 0 Centrosomin N-terminal motif 1 HIP1_clath_bdg PF16515.5 KFP07887.1 - 2.1 9.0 23.0 9.5 6.9 8.0 2.7 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Peptidase_Prp PF04327.12 KFP07887.1 - 3.3 8.0 7.0 0.4 10.9 0.3 2.5 2 1 0 2 2 2 0 Cysteine protease Prp DUF600 PF04634.12 KFP07887.1 - 6.7 6.8 12.3 2.1 8.4 7.7 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF600 Cupin_8 PF13621.6 KFP07887.1 - 6.7 6.3 6.7 8.7 6.0 6.1 1.6 1 1 0 1 1 1 0 Cupin-like domain GHBP PF12772.7 KFP07888.1 - 1.9e-130 434.8 4.8 2.3e-130 434.5 4.8 1.1 1 0 0 1 1 1 1 Growth hormone receptor binding EpoR_lig-bind PF09067.10 KFP07888.1 - 6.5e-13 48.8 3.1 6.5e-13 48.8 3.1 2.4 3 0 0 3 3 3 1 Erythropoietin receptor, ligand binding fn3 PF00041.21 KFP07888.1 - 3.1e-07 30.6 0.2 6.7e-07 29.6 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III domain Nab6_mRNP_bdg PF10567.9 KFP07888.1 - 0.085 12.3 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 RNA-recognition motif IL6Ra-bind PF09240.10 KFP07888.1 - 0.45 11.0 5.2 0.17 12.3 1.6 2.1 2 0 0 2 2 2 0 Interleukin-6 receptor alpha chain, binding I-set PF07679.16 KFP07889.1 - 1.3e-43 147.0 0.0 1e-13 51.1 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP07889.1 - 1.7e-43 147.1 0.2 2e-13 50.7 0.0 4.0 3 0 0 3 3 3 3 Immunoglobulin domain ADAM_spacer1 PF05986.14 KFP07889.1 - 1.8e-34 118.2 0.0 3e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Ig_2 PF13895.6 KFP07889.1 - 1.1e-32 112.2 0.3 7.1e-11 42.3 0.3 4.2 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFP07889.1 - 1.1e-32 112.1 0.2 1.4e-09 38.0 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin domain TSP_1 PF00090.19 KFP07889.1 - 1.4e-24 86.0 68.0 9.8e-09 35.3 12.4 6.0 5 0 0 5 5 5 4 Thrombospondin type 1 domain V-set PF07686.17 KFP07889.1 - 3.5e-23 81.9 6.6 1.5e-06 28.3 0.7 6.6 3 3 2 5 5 5 4 Immunoglobulin V-set domain Kunitz_BPTI PF00014.23 KFP07889.1 - 3.7e-17 62.3 6.1 3.7e-17 62.3 6.1 3.4 3 0 0 3 3 2 1 Kunitz/Bovine pancreatic trypsin inhibitor domain PLAC PF08686.11 KFP07889.1 - 1.6e-10 41.5 7.7 8.4e-10 39.2 7.7 2.4 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Ig_4 PF16680.5 KFP07889.1 - 4.9e-06 26.7 0.0 0.19 12.0 0.0 3.6 3 0 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFP07889.1 - 5e-06 26.5 0.1 0.0022 18.0 0.0 3.2 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFP07889.1 - 6.7e-05 22.4 0.0 1 9.0 0.0 3.6 3 0 0 3 3 3 2 Immunoglobulin domain V-set_CD47 PF08204.11 KFP07889.1 - 0.004 17.1 0.0 0.073 13.1 0.6 2.6 3 1 0 3 3 3 1 CD47 immunoglobulin-like domain C2-set PF05790.15 KFP07889.1 - 0.011 15.9 0.0 2.5 8.3 0.0 3.8 4 0 0 4 4 4 0 Immunoglobulin C2-set domain Invasin_D3 PF09134.10 KFP07889.1 - 0.13 12.6 0.1 10 6.5 0.0 3.0 3 0 0 3 3 3 0 Invasin, domain 3 Presenilin PF01080.17 KFP07890.1 - 1.6e-163 544.1 20.2 8.6e-163 541.7 20.2 1.8 1 1 0 1 1 1 1 Presenilin SLATT_4 PF18186.1 KFP07890.1 - 5.5 6.6 6.6 1.8 8.2 1.0 2.5 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 4 PWI PF01480.17 KFP07891.1 - 3.6e-14 52.8 0.2 7.8e-14 51.7 0.2 1.6 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 KFP07891.1 - 4.4e-09 36.0 0.0 8.3e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FYVE PF01363.21 KFP07892.1 - 3.9e-30 103.8 24.8 2.8e-16 59.4 10.8 5.5 5 1 1 6 6 6 2 FYVE zinc finger GBP PF02263.19 KFP07892.1 - 0.0045 16.3 0.0 0.0084 15.4 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AIG1 PF04548.16 KFP07892.1 - 0.0056 16.0 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 AIG1 family WD40 PF00400.32 KFP07893.1 - 0.00096 19.9 0.2 6.2 7.9 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP07893.1 - 0.007 16.6 0.1 0.09 13.1 0.1 2.5 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP07893.1 - 0.021 13.5 0.0 0.15 10.7 0.0 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Requiem_N PF14051.6 KFP07894.1 - 2.4e-37 127.0 0.4 5.2e-37 125.9 0.4 1.6 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. PHD PF00628.29 KFP07894.1 - 5e-22 77.5 23.4 3.7e-12 45.9 5.2 3.4 2 1 1 3 3 3 2 PHD-finger PHD_4 PF16866.5 KFP07894.1 - 0.011 15.8 9.3 0.011 15.8 9.3 3.7 2 1 1 3 3 3 0 PHD-finger Lar_restr_allev PF14354.6 KFP07894.1 - 0.017 15.5 1.4 0.017 15.5 1.4 4.0 2 1 1 3 3 3 0 Restriction alleviation protein Lar zf-C2H2 PF00096.26 KFP07894.1 - 0.028 14.9 1.4 0.028 14.9 1.4 4.8 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP07894.1 - 0.036 14.9 0.8 0.036 14.9 0.8 5.4 5 1 1 6 6 6 0 C2H2-type zinc finger C1_1 PF00130.22 KFP07894.1 - 0.079 12.9 20.6 0.42 10.5 0.4 4.6 3 1 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 KFP07894.1 - 0.41 10.6 21.5 0.46 10.4 0.5 4.1 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 zf-BED PF02892.15 KFP07894.1 - 0.49 10.4 0.1 0.49 10.4 0.1 3.3 3 1 0 3 3 3 0 BED zinc finger PHD_2 PF13831.6 KFP07894.1 - 1 9.0 20.3 0.078 12.6 1.2 3.9 3 1 1 4 4 4 0 PHD-finger zf-RING_7 PF02591.15 KFP07894.1 - 1.4 9.2 8.6 11 6.3 0.8 3.6 3 1 0 3 3 3 0 C4-type zinc ribbon domain Zf_RING PF16744.5 KFP07894.1 - 1.9 8.7 21.4 12 6.1 5.0 4.8 3 1 1 4 4 4 0 KIAA1045 RING finger RGS_DHEX PF18148.1 KFP07895.1 - 2.4e-50 168.8 1.8 7.8e-50 167.1 1.8 1.9 1 0 0 1 1 1 1 Regulator of G-protein signalling DHEX domain RGS PF00615.19 KFP07895.1 - 3.8e-34 117.5 0.3 3.8e-34 117.5 0.3 2.3 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.21 KFP07895.1 - 1.1e-16 60.7 0.0 2.9e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.22 KFP07895.1 - 1.9e-11 43.8 0.0 5e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 GGL domain RGS-like PF09128.11 KFP07895.1 - 0.024 14.3 0.4 0.081 12.6 0.0 1.9 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain AAA PF00004.29 KFP07897.1 - 2e-12 47.6 0.0 3e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFP07897.1 - 0.00013 22.2 0.0 0.0002 21.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFP07897.1 - 0.00025 21.2 0.0 0.00034 20.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KFP07897.1 - 0.00046 20.0 0.0 0.00063 19.5 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KFP07897.1 - 0.00055 19.9 0.0 0.00077 19.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KFP07897.1 - 0.0015 19.1 0.0 0.0023 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFP07897.1 - 0.0024 17.6 0.0 0.0031 17.2 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 KFP07897.1 - 0.0031 17.9 0.2 0.0044 17.4 0.2 1.3 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 KFP07897.1 - 0.0047 16.3 0.0 0.0072 15.7 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KFP07897.1 - 0.0067 15.7 0.0 0.0087 15.3 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 KFP07897.1 - 0.008 16.2 0.0 0.0085 16.1 0.0 1.2 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 KFP07897.1 - 0.0087 15.9 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KFP07897.1 - 0.022 14.3 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KFP07897.1 - 0.023 15.1 0.0 0.032 14.6 0.0 1.3 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 KFP07897.1 - 0.042 13.3 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 KFP07897.1 - 0.05 13.4 0.0 0.052 13.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFP07897.1 - 0.062 13.2 0.0 0.091 12.7 0.0 1.2 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 KFP07897.1 - 0.066 12.8 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KFP07897.1 - 0.078 12.3 0.0 0.093 12.1 0.0 1.1 1 0 0 1 1 1 0 KaiC AAA_28 PF13521.6 KFP07897.1 - 0.079 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KFP07897.1 - 0.091 12.5 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 Cytidylate kinase AAA_30 PF13604.6 KFP07897.1 - 0.16 11.7 0.0 0.21 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KFP07897.1 - 0.2 10.7 0.0 0.27 10.3 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 KFP07897.1 - 0.25 10.6 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin PDZ PF00595.24 KFP07898.1 - 7.2e-21 74.3 0.1 1.2e-20 73.6 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP07898.1 - 1.3e-10 41.0 0.0 1.8e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP07898.1 - 9.9e-08 32.2 0.0 1.2e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 KFP07898.1 - 0.022 14.7 0.0 0.053 13.5 0.0 1.7 2 0 0 2 2 2 0 Tricorn protease PDZ domain Peptidase_C97 PF05903.14 KFP07899.1 - 1.2e-41 142.0 0.0 1.6e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF3670 PF12419.8 KFP07899.1 - 0.22 11.4 0.0 0.61 9.9 0.0 1.6 2 0 0 2 2 2 0 SNF2 Helicase protein Calx-beta PF03160.14 KFP07901.1 - 2.1e-62 207.5 8.5 1.1e-30 105.7 0.2 2.8 3 0 0 3 3 3 2 Calx-beta domain Na_Ca_ex PF01699.24 KFP07901.1 - 1.5e-58 197.1 35.7 3.1e-33 114.9 13.2 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Na_Ca_ex_C PF16494.5 KFP07901.1 - 1.9e-54 183.5 5.1 4.7e-54 182.3 5.1 1.7 1 0 0 1 1 1 1 C-terminal extension of sodium/calcium exchanger domain Acyl_transf_3 PF01757.22 KFP07901.1 - 1.7 7.6 25.9 0.28 10.2 12.2 2.6 2 0 0 2 2 2 0 Acyltransferase family Thyroglobulin_1 PF00086.18 KFP07902.1 - 3.3e-39 132.4 15.2 7.9e-20 70.3 4.8 2.9 2 0 0 2 2 2 2 Thyroglobulin type-1 repeat Thyroglob_assoc PF16597.5 KFP07902.1 - 1.2e-26 92.8 0.9 2.7e-26 91.7 0.9 1.6 1 0 0 1 1 1 1 Thyroglobulin_1 repeat associated disordered domain SPARC_Ca_bdg PF10591.9 KFP07902.1 - 1.4e-10 41.4 0.0 3.2e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_2 PF07648.15 KFP07902.1 - 4.1e-06 26.8 7.0 4.1e-06 26.8 7.0 4.4 4 1 1 5 5 5 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.6 KFP07902.1 - 0.00013 22.3 0.1 0.0003 21.2 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP07902.1 - 0.0058 16.5 0.1 1 9.5 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KFP07902.1 - 0.017 14.6 0.0 1.8 8.3 0.0 2.5 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 KFP07902.1 - 0.046 13.2 0.0 2.8 7.6 0.0 2.4 2 0 0 2 2 2 0 EF hand Kazal_1 PF00050.21 KFP07902.1 - 0.48 10.5 10.9 0.14 12.2 4.4 3.3 3 0 0 3 3 3 0 Kazal-type serine protease inhibitor domain RRM_1 PF00076.22 KFP07903.1 - 6e-31 106.1 0.1 1.7e-16 59.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFP07903.1 - 3.6e-06 26.9 0.1 0.011 15.8 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.6 KFP07903.1 - 1.9e-05 24.5 0.0 0.00015 21.7 0.0 2.0 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KFP07903.1 - 0.01 15.7 0.0 3.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif DbpA PF03880.15 KFP07903.1 - 0.015 15.2 0.0 9.1 6.4 0.0 2.6 3 0 0 3 3 3 0 DbpA RNA binding domain RRM_5 PF13893.6 KFP07903.1 - 0.086 12.4 0.0 5.1 6.7 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4551 PF15087.6 KFP07903.1 - 6 5.6 12.5 7.3 5.3 12.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Sushi PF00084.20 KFP07904.1 - 2.9e-07 31.0 6.3 4.9e-07 30.3 6.3 1.4 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) DUF4659 PF15558.6 KFP07905.1 - 2.1e-103 346.1 106.0 1e-94 317.5 97.3 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4659) RVT_1 PF00078.27 KFP07906.1 - 0.068 12.7 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) HAT_KAT11 PF08214.11 KFP07907.1 - 3.3e-69 233.8 0.7 6.2e-69 232.9 0.7 1.4 1 0 0 1 1 1 1 Histone acetylation protein Creb_binding PF09030.10 KFP07907.1 - 6.6e-32 110.4 14.4 6.6e-32 110.4 14.4 7.7 3 2 5 9 9 9 1 Creb binding DUF902 PF06001.13 KFP07907.1 - 2.2e-22 79.3 9.2 2.2e-22 79.3 9.2 2.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF902) Bromodomain PF00439.25 KFP07907.1 - 2.9e-17 62.5 0.0 7.9e-17 61.1 0.0 1.7 1 0 0 1 1 1 1 Bromodomain ZZ PF00569.17 KFP07907.1 - 8.3e-16 57.5 14.6 8.3e-16 57.5 14.6 3.5 4 0 0 4 4 4 1 Zinc finger, ZZ type zf-TAZ PF02135.16 KFP07907.1 - 2.8e-12 46.9 25.8 2.8e-12 46.9 25.8 2.9 3 0 0 3 3 3 1 TAZ zinc finger Npa1 PF11707.8 KFP07907.1 - 0.0045 16.4 0.0 0.0082 15.5 0.0 1.3 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal CPSF100_C PF13299.6 KFP07907.1 - 1.1 9.4 4.7 3.2 7.9 4.7 1.8 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.14 KFP07907.1 - 1.4 7.1 7.4 2.3 6.4 7.4 1.2 1 0 0 1 1 1 0 CDC45-like protein HSP90 PF00183.18 KFP07907.1 - 1.5 7.7 10.0 2.8 6.7 10.0 1.4 1 0 0 1 1 1 0 Hsp90 protein HSP90 PF00183.18 KFP07908.1 - 3e-101 339.9 6.1 4.9e-96 322.7 2.1 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 KFP07908.1 - 2.5e-11 43.6 0.0 1.4e-10 41.2 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KFP07908.1 - 3e-08 34.2 0.1 5.5e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BTB PF00651.31 KFP07909.1 - 3.3e-11 43.4 0.0 5.6e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Slx4 PF09494.10 KFP07910.1 - 1.1e-16 60.5 0.0 1.6e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Slx4 endonuclease SAP PF02037.27 KFP07910.1 - 0.26 11.1 1.0 2.2 8.1 0.2 2.2 2 0 0 2 2 2 0 SAP domain Heme_oxygenase PF01126.20 KFP07911.1 - 1.4e-82 276.5 5.6 1.6e-82 276.2 5.6 1.1 1 0 0 1 1 1 1 Heme oxygenase zf-LITAF-like PF10601.9 KFP07912.1 - 7.8e-24 83.7 16.3 1.1e-23 83.3 16.3 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-C3HC4_3 PF13920.6 KFP07915.1 - 1.8e-14 53.3 9.4 2.8e-14 52.7 9.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP07915.1 - 8.7e-07 28.7 10.2 1.6e-06 27.9 10.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KFP07915.1 - 7.3e-06 26.2 11.7 1.3e-05 25.4 11.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFP07915.1 - 0.0005 20.0 9.5 0.00089 19.2 9.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFP07915.1 - 0.0017 18.1 11.3 0.003 17.4 11.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KFP07915.1 - 1.9 8.3 8.3 3.3 7.6 8.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 KFP07915.1 - 8.7 6.1 13.0 23 4.7 13.0 1.7 1 1 0 1 1 1 0 P-11 zinc finger DUF4507 PF14964.6 KFP07916.1 - 3.7e-128 427.4 0.3 4.3e-128 427.2 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4507) Exo_endo_phos PF03372.23 KFP07917.1 - 8.5e-05 22.2 0.0 0.00011 21.8 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NanE PF04131.14 KFP07917.1 - 0.024 13.8 0.0 0.083 12.1 0.0 1.7 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Exo_endo_phos PF03372.23 KFP07918.1 - 8.8e-10 38.5 0.0 1.1e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UPF0114 PF03350.16 KFP07918.1 - 0.048 13.9 0.0 0.08 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 ECH_1 PF00378.20 KFP07919.1 - 3.1e-78 262.5 0.0 3.9e-78 262.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFP07919.1 - 1.6e-13 50.9 0.0 2.1e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase YwhD PF08741.10 KFP07919.1 - 0.015 15.0 0.2 0.026 14.2 0.2 1.3 1 0 0 1 1 1 0 YwhD family Voltage_CLC PF00654.20 KFP07920.1 - 2e-96 323.4 29.8 2.7e-96 322.9 25.5 2.0 1 1 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 KFP07920.1 - 9e-15 54.9 0.2 2.4e-10 40.7 0.0 2.5 2 0 0 2 2 2 2 CBS domain LUC7 PF03194.15 KFP07921.1 - 3.9e-72 243.0 13.6 3.9e-72 243.0 13.6 2.2 1 1 1 2 2 2 1 LUC7 N_terminus TSC22 PF01166.18 KFP07921.1 - 0.49 10.8 3.8 8.8 6.7 0.2 2.9 2 1 1 3 3 3 0 TSC-22/dip/bun family PQQ_2 PF13360.6 KFP07922.1 - 8.6e-06 25.5 0.1 0.0043 16.7 0.0 2.5 2 0 0 2 2 2 2 PQQ-like domain FG-GAP PF01839.23 KFP07922.1 - 0.0028 17.7 1.0 0.27 11.4 0.4 2.5 2 0 0 2 2 2 1 FG-GAP repeat PQQ PF01011.21 KFP07922.1 - 0.033 14.1 0.0 0.17 11.9 0.0 2.2 2 0 0 2 2 2 0 PQQ enzyme repeat VCBS PF13517.6 KFP07922.1 - 0.054 14.1 0.1 2 9.1 0.0 2.6 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF3413 PF11893.8 KFP07922.1 - 0.069 12.3 0.2 0.1 11.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) PQQ_3 PF13570.6 KFP07922.1 - 0.2 12.2 1.0 23 5.7 0.0 3.2 3 0 0 3 3 3 0 PQQ-like domain RGS_DHEX PF18148.1 KFP07923.1 - 6.7e-38 128.8 0.4 1.7e-37 127.6 0.4 1.7 1 0 0 1 1 1 1 Regulator of G-protein signalling DHEX domain RGS PF00615.19 KFP07923.1 - 8.4e-33 113.1 0.1 1.4e-32 112.5 0.1 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 KFP07923.1 - 2.3e-08 34.0 0.0 6.1e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.22 KFP07923.1 - 4.9e-08 32.9 0.2 6.3e-06 26.1 0.1 2.4 2 0 0 2 2 2 2 GGL domain Rho_GDI PF02115.17 KFP07924.1 - 1.9e-63 213.8 0.0 2.3e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Thioredoxin PF00085.20 KFP07925.1 - 1.2e-49 166.6 0.0 1.5e-26 92.3 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KFP07925.1 - 9.8e-42 142.9 0.0 1.2e-36 126.4 0.0 2.9 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFP07925.1 - 6.7e-12 45.4 0.2 2.5e-05 24.4 0.1 2.8 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KFP07925.1 - 2.1e-09 37.8 0.0 0.00049 20.5 0.0 2.9 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFP07925.1 - 6.6e-07 29.6 0.1 0.12 12.7 0.0 3.9 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 KFP07925.1 - 1.9e-06 27.8 0.3 0.072 13.0 0.0 2.8 3 0 0 3 3 3 2 AhpC/TSA family TraF PF13728.6 KFP07925.1 - 5.4e-05 23.1 0.0 0.043 13.6 0.0 2.6 3 0 0 3 3 3 2 F plasmid transfer operon protein Glutaredoxin PF00462.24 KFP07925.1 - 0.0016 18.6 0.1 0.2 11.9 0.0 3.1 4 0 0 4 4 4 1 Glutaredoxin Redoxin PF08534.10 KFP07925.1 - 0.014 15.1 0.2 3.1 7.5 0.0 2.9 3 0 0 3 3 3 0 Redoxin Thioredoxin_9 PF14595.6 KFP07925.1 - 0.027 14.3 0.0 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin DIX PF00778.17 KFP07926.1 - 2.6e-31 107.3 1.1 4.6e-31 106.5 1.1 1.4 1 0 0 1 1 1 1 DIX domain RGS PF00615.19 KFP07926.1 - 1.4e-27 96.3 0.4 2.8e-27 95.3 0.4 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain AXIN1_TNKS_BD PF16646.5 KFP07926.1 - 2.4e-25 89.2 3.6 1.3e-24 86.9 3.6 2.4 1 0 0 1 1 1 1 Axin-1 tankyrase binding domain Axin_b-cat_bind PF08833.10 KFP07926.1 - 7.5e-11 42.0 0.0 3e-10 40.0 0.0 2.1 1 0 0 1 1 1 1 Axin beta-catenin binding domain Cwf_Cwc_15 PF04889.12 KFP07926.1 - 0.94 9.2 6.1 0.4 10.4 1.3 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ribosomal_L28 PF00830.19 KFP07927.1 - 8.2e-05 22.7 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal L28 family DUF3522 PF12036.8 KFP07928.1 - 1.2e-63 214.8 19.6 1.2e-63 214.8 19.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3522) DUF456 PF04306.13 KFP07928.1 - 1.2 9.4 6.3 0.71 10.2 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF456) LptF_LptG PF03739.14 KFP07928.1 - 1.2 7.9 5.6 2 7.2 5.6 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Globin PF00042.22 KFP07929.1 - 3.9e-30 104.7 0.0 5.1e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Globin 5_3_exonuc PF01367.20 KFP07929.1 - 0.039 14.6 0.0 0.054 14.1 0.0 1.3 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Globin PF00042.22 KFP07930.1 - 1.1e-27 96.7 0.0 3.3e-27 95.2 0.0 1.7 2 0 0 2 2 2 1 Globin Abi_C PF14355.6 KFP07930.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Abortive infection C-terminus Globin PF00042.22 KFP07932.1 - 6.3e-29 100.7 0.0 8.6e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 Globin NPR3 PF03666.13 KFP07933.1 - 2.3e-38 132.2 8.6 3.1e-28 98.8 7.8 3.6 1 1 1 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 KFP07933.1 - 0.0045 15.8 0.4 0.053 12.3 0.4 2.2 1 1 0 1 1 1 1 Nitrogen permease regulator 2 Pur_DNA_glyco PF02245.16 KFP07934.1 - 1.8e-58 196.8 0.0 2.2e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) Rhomboid_SP PF12595.8 KFP07935.1 - 4.9e-113 375.8 1.6 7.5e-113 375.2 1.6 1.3 1 0 0 1 1 1 1 Rhomboid serine protease Rhomboid PF01694.22 KFP07935.1 - 6.2e-28 97.7 9.1 6.2e-28 97.7 9.1 1.8 3 0 0 3 3 3 1 Rhomboid family Herpes_UL56 PF04534.12 KFP07935.1 - 0.011 15.3 1.0 0.015 14.8 0.1 1.7 2 0 0 2 2 2 0 Herpesvirus UL56 protein DUF4457 PF14652.6 KFP07936.1 - 2.2e-229 760.0 0.1 1.1e-148 494.8 0.0 4.2 3 2 1 4 4 4 4 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 KFP07936.1 - 3.5e-07 30.3 0.0 2.3 8.2 0.0 5.0 5 0 0 5 5 5 3 Sad1 / UNC-like C-terminal GSG-1 PF07803.11 KFP07937.1 - 5.1e-51 171.5 0.3 8.7e-51 170.7 0.3 1.4 1 0 0 1 1 1 1 GSG1-like protein PMP22_Claudin PF00822.20 KFP07937.1 - 4.9e-07 29.8 13.5 5.7e-07 29.6 4.6 2.4 2 1 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP07937.1 - 1.1e-05 25.3 12.0 4.5e-05 23.3 12.0 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction TMEM191C PF15194.6 KFP07937.1 - 0.37 11.0 1.4 0.65 10.2 1.4 1.3 1 0 0 1 1 1 0 TMEM191C family CD20 PF04103.15 KFP07937.1 - 0.99 9.5 15.0 13 5.8 8.3 3.7 3 1 0 3 3 3 0 CD20-like family Tissue_fac PF01108.17 KFP07938.1 - 2.3e-20 72.4 1.2 6.7e-20 70.9 0.1 2.2 3 0 0 3 3 3 1 Tissue factor Interfer-bind PF09294.10 KFP07938.1 - 1.4e-11 44.6 0.8 5.3e-11 42.7 0.8 1.9 1 1 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.21 KFP07938.1 - 5.8e-05 23.4 0.2 0.39 11.1 0.0 2.5 2 1 0 2 2 2 2 Fibronectin type III domain DUF4448 PF14610.6 KFP07938.1 - 0.072 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Fox-1_C PF12414.8 KFP07940.1 - 1.9e-43 146.7 22.8 1.9e-43 146.7 22.8 2.5 2 0 0 2 2 2 1 Calcitonin gene-related peptide regulator C terminal RRM_1 PF00076.22 KFP07940.1 - 1.5e-18 66.3 0.1 3.4e-18 65.2 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPESP1 PF15754.5 KFP07940.1 - 0.013 14.8 4.1 0.019 14.2 4.1 1.2 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 RRM_5 PF13893.6 KFP07940.1 - 0.054 13.1 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UBN_AB PF14075.6 KFP07941.1 - 4.3e-83 278.3 1.7 4.3e-83 278.3 1.7 3.2 3 1 0 3 3 3 1 Ubinuclein conserved middle domain HUN PF08729.10 KFP07941.1 - 1.8e-19 69.5 0.7 1.8e-19 69.5 0.7 2.4 3 0 0 3 3 3 1 HPC2 and ubinuclein domain CpxA_peri PF16527.5 KFP07941.1 - 0.14 12.5 2.4 3.7 7.9 1.2 2.7 2 0 0 2 2 2 0 Two-component sensor protein CpxA, periplasmic domain Cellulose_synt PF03552.14 KFP07941.1 - 3.3 6.1 3.7 5.4 5.4 3.7 1.2 1 0 0 1 1 1 0 Cellulose synthase PDZ PF00595.24 KFP07942.1 - 5.6e-11 42.6 0.1 1.4e-10 41.3 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP07942.1 - 0.0071 16.2 0.1 0.029 14.2 0.0 2.1 2 0 0 2 2 2 1 PDZ domain CCDC74_C PF14917.6 KFP07942.1 - 0.23 12.0 5.5 0.35 11.4 4.8 1.7 1 1 0 1 1 1 0 Coiled coil protein 74, C terminal DUF1192 PF06698.11 KFP07942.1 - 0.31 11.1 6.4 1.9 8.6 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TPR_MLP1_2 PF07926.12 KFP07942.1 - 0.38 10.8 22.8 0.049 13.7 11.1 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein PKcGMP_CC PF16808.5 KFP07942.1 - 0.42 10.5 5.3 9.6 6.2 0.8 3.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Laminin_II PF06009.12 KFP07942.1 - 0.56 10.2 10.0 1.1 9.3 10.0 1.5 1 0 0 1 1 1 0 Laminin Domain II Med9 PF07544.13 KFP07942.1 - 0.58 10.3 7.2 0.21 11.7 3.0 2.3 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4763 PF15960.5 KFP07942.1 - 0.64 9.3 15.6 0.1 11.9 8.2 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4763) DUF5082 PF16888.5 KFP07942.1 - 0.98 9.7 9.0 1.9 8.8 9.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) GIT_CC PF16559.5 KFP07942.1 - 1.9 8.4 13.1 35 4.3 4.3 3.7 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor ERM PF00769.19 KFP07942.1 - 4.4 7.1 19.4 7.9 6.2 19.4 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Spc7 PF08317.11 KFP07942.1 - 9.1 5.1 19.1 0.69 8.7 8.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein PRELI PF04707.14 KFP07943.1 - 6.2e-45 152.8 0.1 2e-44 151.2 0.6 1.6 2 0 0 2 2 2 1 PRELI-like family CRAL_TRIO PF00650.20 KFP07943.1 - 1.5e-42 145.0 0.0 3e-42 144.0 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFP07943.1 - 2.1e-07 31.0 0.1 5.3e-07 29.7 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain NAGPA PF09992.9 KFP07944.1 - 4.6e-39 134.3 0.1 5.9e-39 134.0 0.1 1.1 1 0 0 1 1 1 1 Phosphodiester glycosidase EGF_2 PF07974.13 KFP07944.1 - 0.0058 17.0 28.7 0.0089 16.4 11.3 4.8 3 1 0 3 3 3 3 EGF-like domain EGF_Tenascin PF18720.1 KFP07944.1 - 0.03 14.4 9.9 0.03 14.4 9.9 3.7 3 0 0 3 3 3 0 Tenascin EGF domain Glycos_transf_1 PF00534.20 KFP07945.1 - 6.4e-07 29.1 0.0 9.3e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFP07945.1 - 5.7e-06 26.8 0.0 8.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFP07945.1 - 0.0018 18.3 0.0 0.0028 17.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 MISS PF15822.5 KFP07945.1 - 0.01 15.7 0.2 0.015 15.2 0.2 1.1 1 0 0 1 1 1 0 MAPK-interacting and spindle-stabilising protein-like Glyco_trans_1_2 PF13524.6 KFP07945.1 - 0.054 13.9 0.0 0.09 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KFP07945.1 - 0.06 13.8 0.0 0.096 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Methyltransf_16 PF10294.9 KFP07946.1 - 7.8e-19 68.1 0.1 7e-16 58.4 0.1 2.1 1 1 0 1 1 1 1 Lysine methyltransferase Met_10 PF02475.16 KFP07946.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_25 PF13649.6 KFP07946.1 - 0.036 14.8 0.0 0.057 14.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KFP07946.1 - 0.071 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 KFP07946.1 - 0.14 12.9 0.0 0.31 11.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Peptidase_C2 PF00648.21 KFP07947.1 - 1.2e-80 270.8 0.0 1.7e-80 270.2 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease zf-RanBP PF00641.18 KFP07947.1 - 5.5e-23 80.0 48.7 2.5e-07 29.9 2.0 6.0 5 0 0 5 5 5 5 Zn-finger in Ran binding protein and others DZR PF12773.7 KFP07947.1 - 0.0029 17.6 51.2 0.083 12.9 8.0 5.3 5 0 0 5 5 5 4 Double zinc ribbon Vps36-NZF-N PF16988.5 KFP07947.1 - 2.8 7.4 36.9 0.57 9.6 0.4 6.6 6 1 0 6 6 6 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF3615 PF12274.8 KFP07947.1 - 8.3 7.0 16.0 6.5 7.4 0.1 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3615) zf-C2H2_7 PF15269.6 KFP07949.1 - 1.7e-38 130.5 11.7 4.3e-38 129.2 11.7 1.7 1 0 0 1 1 1 1 Zinc-finger NHL PF01436.21 KFP07949.1 - 1.2e-17 62.9 2.6 0.0014 18.6 0.1 5.0 5 0 0 5 5 5 4 NHL repeat SGL PF08450.12 KFP07949.1 - 3.4e-05 23.6 0.1 0.17 11.4 0.0 2.7 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region zf-H2C2_5 PF13909.6 KFP07949.1 - 0.025 14.3 6.7 0.059 13.1 6.7 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KFP07949.1 - 9.6 7.4 9.2 55 5.0 4.7 3.3 2 0 0 2 2 2 0 C2H2-type zinc finger Gpi1 PF05024.15 KFP07950.1 - 3.3e-44 151.2 4.3 3.3e-44 151.2 4.3 2.0 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Ras PF00071.22 KFP07951.1 - 1e-33 116.3 0.0 1.3e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP07951.1 - 5.8e-14 52.3 0.0 8.6e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SOCS_box PF07525.16 KFP07951.1 - 1.4e-07 31.7 0.4 2.7e-07 30.8 0.4 1.5 1 0 0 1 1 1 1 SOCS box Arf PF00025.21 KFP07951.1 - 0.0096 15.4 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Kunitz_BPTI PF00014.23 KFP07952.1 - 3.1e-35 120.2 18.5 1.6e-19 69.9 4.8 2.4 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain NTR PF01759.21 KFP07952.1 - 1.6e-08 34.3 0.0 3.1e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Tcell_CD4_C PF12104.8 KFP07952.1 - 0.0013 18.6 0.3 0.0045 16.9 0.3 2.0 1 0 0 1 1 1 1 T cell CD4 receptor C terminal region DUF938 PF06080.12 KFP07953.1 - 1.1e-27 97.2 0.0 1.2e-27 97.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_12 PF08242.12 KFP07953.1 - 0.2 12.4 0.0 0.22 12.3 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain FAM195 PF14799.6 KFP07954.1 - 8.4e-32 109.6 0.2 9.2e-32 109.5 0.2 1.0 1 0 0 1 1 1 1 FAM195 family LAP2alpha PF11560.8 KFP07954.1 - 0.031 13.7 0.0 0.035 13.5 0.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 2 alpha ABC2_membrane_3 PF12698.7 KFP07955.1 - 1.1e-60 205.6 42.6 1.1e-35 123.4 24.5 2.4 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 KFP07955.1 - 3.3e-48 163.7 0.0 5.2e-23 82.1 0.0 2.8 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 KFP07955.1 - 2.3e-18 67.0 0.1 2e-05 24.6 0.0 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFP07955.1 - 0.00018 21.4 0.7 0.0055 16.6 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 KFP07955.1 - 0.00085 19.9 4.3 0.037 14.5 0.1 3.0 3 0 0 3 3 3 1 AAA domain DUF4162 PF13732.6 KFP07955.1 - 0.0023 18.6 0.0 0.3 11.8 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) SbcCD_C PF13558.6 KFP07955.1 - 0.0077 16.4 0.0 0.22 11.8 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 KFP07955.1 - 0.012 15.3 0.3 0.71 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KFP07955.1 - 0.021 14.9 0.4 1.3 9.1 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.6 KFP07955.1 - 0.024 14.9 1.9 1.5 9.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 KFP07955.1 - 0.026 14.2 0.0 0.27 10.9 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.6 KFP07955.1 - 0.034 13.9 2.3 0.33 10.7 0.2 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KFP07955.1 - 0.047 14.1 0.3 1.7 9.0 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain Arf PF00025.21 KFP07955.1 - 0.063 12.7 0.5 12 5.3 0.1 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family SRP54 PF00448.22 KFP07955.1 - 0.11 12.1 4.8 1 9.0 0.4 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Rad17 PF03215.15 KFP07955.1 - 0.12 12.3 0.0 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_24 PF13479.6 KFP07955.1 - 0.2 11.4 2.2 26 4.5 0.1 3.1 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 KFP07955.1 - 0.54 9.8 2.4 10 5.7 0.1 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Pkinase PF00069.25 KFP07956.1 - 6.9e-11 42.0 0.0 7.6e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP07956.1 - 5.2e-06 25.9 0.0 6.4e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP07956.1 - 2.9e-05 23.0 0.0 3.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF4693 PF15764.5 KFP07957.1 - 5.3e-93 311.7 6.9 6.3e-93 311.4 6.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4693) fn3 PF00041.21 KFP07958.1 - 7.3e-10 39.1 0.1 1.4e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Ank_4 PF13637.6 KFP07958.1 - 0.0033 18.0 0.0 0.0069 16.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Pur_ac_phosph_N PF16656.5 KFP07958.1 - 0.0059 17.2 1.0 0.031 14.8 1.0 2.1 1 1 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Ank_5 PF13857.6 KFP07958.1 - 0.0094 16.3 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP07958.1 - 0.12 13.0 0.0 0.25 12.0 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Retrotrans_gag PF03732.17 KFP07959.1 - 0.015 15.6 1.6 0.031 14.6 1.6 1.6 1 1 0 1 1 1 0 Retrotransposon gag protein MHB PF16525.5 KFP07959.1 - 0.087 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 Haemophore, haem-binding DUF3138 PF11336.8 KFP07959.1 - 0.23 10.0 0.0 0.3 9.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Zn-C2H2_12 PF18112.1 KFP07960.1 - 0.18 12.3 0.0 0.94 10.0 0.0 1.9 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Laminin_N PF00055.17 KFP07961.1 - 1.6e-70 237.4 0.0 1.6e-70 237.4 0.0 4.2 3 2 1 4 4 4 1 Laminin N-terminal (Domain VI) NTR PF01759.21 KFP07961.1 - 2.7e-29 101.1 1.6 4.9e-29 100.3 1.6 1.4 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Laminin_EGF PF00053.24 KFP07961.1 - 1.8e-20 72.8 57.9 2e-11 43.8 12.0 5.0 4 1 1 5 5 5 3 Laminin EGF domain RabGAP-TBC PF00566.18 KFP07962.1 - 1.7e-24 86.7 0.0 2.6e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TLD PF07534.16 KFP07962.1 - 7.1e-24 84.6 0.1 1.8e-10 41.2 0.0 2.4 2 0 0 2 2 2 2 TLD ATP-synt_C PF00137.21 KFP07963.1 - 2.9e-35 120.4 32.3 1.2e-22 80.0 14.1 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Amidohydro_1 PF01979.20 KFP07964.1 - 9.3e-20 71.2 0.5 1.2e-19 70.9 0.5 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFP07964.1 - 1.6e-06 27.9 0.2 6.3e-06 25.9 0.0 2.0 3 0 0 3 3 3 1 Amidohydrolase family DUF4615 PF15393.6 KFP07965.1 - 1.9e-42 145.1 2.7 1.9e-42 145.1 2.7 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4615) NopRA1 PF16201.5 KFP07965.1 - 0.76 9.3 3.7 1.6 8.3 3.7 1.4 1 1 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 Vfa1 PF08432.10 KFP07965.1 - 0.86 9.9 17.9 1.3 9.3 17.9 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PDE4_UCR PF18100.1 KFP07965.1 - 1 10.0 8.0 1.3 9.7 6.1 2.2 1 1 1 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) Zip PF02535.22 KFP07965.1 - 6.5 5.9 5.3 6.2 5.9 5.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RRM_1 PF00076.22 KFP07966.1 - 2.7e-20 72.0 0.0 4e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KFP07966.1 - 0.00034 20.6 0.0 0.00094 19.2 0.0 1.8 1 0 0 1 1 1 1 Limkain b1 RRM_3 PF08777.11 KFP07966.1 - 0.0012 18.9 0.0 0.0037 17.3 0.0 1.8 1 1 0 1 1 1 1 RNA binding motif SPX PF03105.19 KFP07966.1 - 0.0014 18.7 29.9 0.0015 18.5 29.9 1.1 1 0 0 1 1 1 1 SPX domain Nup35_RRM_2 PF14605.6 KFP07966.1 - 0.0018 18.2 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Macoilin PF09726.9 KFP07966.1 - 0.0024 16.5 26.7 0.003 16.2 26.7 1.1 1 0 0 1 1 1 1 Macoilin family RRM_5 PF13893.6 KFP07966.1 - 0.0029 17.2 0.0 0.0069 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP07966.1 - 0.0037 17.4 0.0 0.0086 16.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 KFP07966.1 - 0.0048 16.7 0.0 0.0085 15.9 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif LAP1C PF05609.12 KFP07966.1 - 0.084 12.0 18.6 0.12 11.5 18.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Peptidase_S64 PF08192.11 KFP07966.1 - 2.8 6.3 23.9 3.2 6.1 23.9 1.0 1 0 0 1 1 1 0 Peptidase family S64 PAP1 PF08601.10 KFP07966.1 - 4.5 6.9 35.5 6.1 6.5 35.5 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 BUD22 PF09073.10 KFP07966.1 - 7.8 5.7 37.5 11 5.3 37.5 1.1 1 0 0 1 1 1 0 BUD22 PI3K_1B_p101 PF10486.9 KFP07966.1 - 8.2 4.1 22.5 10 3.7 22.5 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Ndc1_Nup PF09531.10 KFP07966.1 - 8.9 4.9 20.6 13 4.3 20.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Telomere_reg-2 PF10193.9 KFP07967.1 - 4.6e-35 120.4 0.8 9.4e-35 119.4 0.2 1.9 2 0 0 2 2 2 1 Telomere length regulation protein RIX1 PF08167.12 KFP07967.1 - 0.003 17.3 2.1 0.52 10.0 0.0 3.0 4 0 0 4 4 4 2 rRNA processing/ribosome biogenesis L_HMGIC_fpl PF10242.9 KFP07968.1 - 0.0001 22.6 2.2 0.0001 22.6 2.2 2.5 1 1 1 2 2 2 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 KFP07968.1 - 0.00015 21.6 8.0 0.0024 17.7 8.0 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.12 KFP07968.1 - 0.00039 20.0 0.1 0.00039 20.0 0.1 2.2 3 1 0 3 3 3 1 Clc-like Claudin_3 PF06653.11 KFP07968.1 - 0.0011 18.9 4.6 0.22 11.4 0.1 2.4 2 0 0 2 2 2 2 Tight junction protein, Claudin-like DUF4418 PF14387.6 KFP07968.1 - 0.0071 16.5 1.1 0.0071 16.5 1.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4418) SUR7 PF06687.12 KFP07968.1 - 0.014 15.0 1.5 0.038 13.6 1.5 1.8 1 1 0 1 1 1 0 SUR7/PalI family PulG PF11773.8 KFP07968.1 - 0.26 11.2 0.1 0.26 11.2 0.1 1.9 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin Neurensin PF14927.6 KFP07968.1 - 0.65 9.7 3.3 0.77 9.5 0.2 2.4 1 1 1 2 2 2 0 Neurensin Myb_DNA-bind_7 PF15963.5 KFP07969.1 - 0.0051 16.7 0.2 0.011 15.6 0.2 1.5 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KFP07969.1 - 0.021 15.0 0.1 0.087 13.0 0.1 2.2 1 1 0 1 1 1 0 Myb-like DNA-binding domain JUPITER PF17054.5 KFP07970.1 - 3.6e-08 33.3 6.7 2e-05 24.3 0.1 3.6 2 1 2 4 4 4 3 Microtubule-Associated protein Jupiter MBDa PF16564.5 KFP07970.1 - 0.03 14.5 0.0 0.65 10.2 0.0 2.3 2 0 0 2 2 2 0 p55-binding region of Methyl-CpG-binding domain proteins MBD MRP-S34 PF16053.5 KFP07971.1 - 5.6e-54 181.3 0.2 7.4e-54 180.9 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 NAD_binding_2 PF03446.15 KFP07972.1 - 4.8e-39 134.1 0.0 1e-38 133.0 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFP07972.1 - 6.9e-23 81.2 1.1 1.2e-22 80.4 1.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PWWP PF00855.17 KFP07972.1 - 3.3e-14 53.0 0.4 1e-13 51.5 0.4 1.9 1 0 0 1 1 1 1 PWWP domain F420_oxidored PF03807.17 KFP07972.1 - 9.2e-08 32.6 0.0 2.4e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KFP07972.1 - 9e-05 21.9 0.0 0.0008 18.8 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KFP07972.1 - 0.00025 21.1 0.0 0.00049 20.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KFP07972.1 - 0.00039 20.1 0.0 0.00071 19.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KFP07972.1 - 0.003 17.5 0.1 0.0076 16.1 0.1 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KFP07972.1 - 0.033 14.5 0.0 0.087 13.1 0.0 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 KFP07972.1 - 0.13 12.2 0.3 0.44 10.5 0.0 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AT_hook PF02178.19 KFP07972.1 - 4.2 7.6 11.9 0.099 12.6 4.1 2.6 2 0 0 2 2 2 0 AT hook motif Rogdi_lz PF10259.9 KFP07973.1 - 1.2e-49 169.2 0.6 1.4e-49 169.0 0.6 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Synaptonemal_3 PF15191.6 KFP07974.1 - 1.2 8.9 16.8 0.64 9.8 0.2 5.1 3 2 2 5 5 5 0 Synaptonemal complex central element protein 3 FlaC_arch PF05377.11 KFP07974.1 - 1.5 9.3 20.6 0.14 12.6 1.5 4.7 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) PI_PP_I PF18363.1 KFP07974.1 - 2.1 8.6 9.5 0.57 10.4 0.6 3.2 3 0 0 3 3 3 0 Phosphoinositide phosphatase insertion domain Baculo_PEP_C PF04513.12 KFP07974.1 - 9.3 6.3 20.1 3.5 7.7 4.7 3.3 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF937 PF06078.11 KFP07975.1 - 0.039 14.6 0.1 0.29 11.7 0.0 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF937) Bcl-2 PF00452.19 KFP07975.1 - 5.9 7.6 6.8 4 8.2 0.0 4.0 3 1 0 3 3 3 0 Apoptosis regulator proteins, Bcl-2 family Ras PF00071.22 KFP07976.1 - 1.9e-50 170.6 0.0 2.2e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP07976.1 - 6.3e-19 68.4 0.0 8.5e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP07976.1 - 2.5e-05 23.8 0.0 3.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP07976.1 - 0.022 14.3 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain CagD PF16567.5 KFP07976.1 - 0.029 14.1 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 Pathogenicity island component CagD Lipase_3 PF01764.25 KFP07977.1 - 1.4e-15 57.4 0.0 2.2e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KFP07977.1 - 0.088 13.4 0.0 0.25 11.9 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family ER_lumen_recept PF00810.18 KFP07978.1 - 4e-54 183.4 9.1 4e-54 183.4 9.1 1.3 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KFP07978.1 - 0.031 14.1 1.3 0.031 14.1 1.3 2.7 3 2 1 4 4 4 0 PQ loop repeat FliG_M PF14841.6 KFP07979.1 - 0.01 16.0 0.0 12 6.2 0.0 3.4 3 0 0 3 3 3 0 FliG middle domain DUF3240 PF11582.8 KFP07979.1 - 0.21 11.8 1.0 1.8 8.7 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3240) DREV PF05219.12 KFP07980.1 - 2.7e-135 449.6 0.0 3e-135 449.4 0.0 1.0 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.6 KFP07980.1 - 3.6e-12 46.4 0.0 5.4e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP07980.1 - 5.5e-09 36.7 0.0 8.8e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP07980.1 - 1.3e-06 28.9 0.0 2.4e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP07980.1 - 6.5e-06 26.8 0.0 1.3e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP07980.1 - 0.032 14.0 0.0 0.091 12.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_PK PF05891.12 KFP07980.1 - 0.076 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase MTS PF05175.14 KFP07980.1 - 0.14 11.7 0.0 3.2 7.3 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase small domain V-set PF07686.17 KFP07981.1 - 2.9e-06 27.4 0.4 1.4e-05 25.2 0.4 2.0 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFP07981.1 - 0.011 15.8 0.5 0.025 14.7 0.5 1.6 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFP07981.1 - 0.032 14.3 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP07981.1 - 0.034 14.7 0.1 0.074 13.7 0.1 1.7 1 0 0 1 1 1 0 Immunoglobulin domain DUF1652 PF07865.11 KFP07981.1 - 0.11 12.3 0.2 1.8 8.5 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1652) ETRAMP PF09716.10 KFP07981.1 - 0.78 9.8 3.9 1.6 8.9 0.7 2.4 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) MFS_2 PF13347.6 KFP07982.1 - 1.2e-35 122.9 23.7 1.4e-35 122.7 23.7 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein Vps51 PF08700.11 KFP07983.1 - 0.0014 18.7 3.6 0.0014 18.7 3.6 4.2 3 2 1 4 4 4 1 Vps51/Vps67 ZapB PF06005.12 KFP07983.1 - 0.0026 18.2 1.3 0.0026 18.2 1.3 6.4 4 3 2 6 6 6 1 Cell division protein ZapB DUF5082 PF16888.5 KFP07983.1 - 0.0041 17.4 0.6 0.0041 17.4 0.6 4.5 5 1 1 6 6 6 1 Domain of unknown function (DUF5082) Jnk-SapK_ap_N PF09744.9 KFP07983.1 - 0.0089 16.3 16.9 0.0089 16.3 16.9 3.8 2 1 1 3 3 3 2 JNK_SAPK-associated protein-1 DUF3450 PF11932.8 KFP07983.1 - 0.015 14.6 4.3 0.015 14.6 4.3 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF3450) UPF0242 PF06785.11 KFP07983.1 - 0.15 12.2 39.1 1.7 8.7 6.8 3.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF4795 PF16043.5 KFP07983.1 - 0.32 10.6 32.9 0.72 9.4 1.0 4.5 3 2 1 4 4 4 0 Domain of unknown function (DUF4795) ATG16 PF08614.11 KFP07983.1 - 0.86 9.8 43.9 0.84 9.8 16.5 3.5 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF724 PF05266.14 KFP07983.1 - 1.2 8.9 28.7 0.18 11.6 4.2 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 KFP07983.1 - 1.3 9.1 20.2 1.3 9.0 8.5 3.5 3 2 0 3 3 3 0 Protein of unknown function (DUF1664) Hrs_helical PF12210.8 KFP07983.1 - 1.5 9.5 28.0 0.34 11.5 1.5 5.1 4 1 1 5 5 5 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF4618 PF15397.6 KFP07983.1 - 4.3 6.7 40.6 0.12 11.8 16.1 4.0 2 2 2 4 4 4 0 Domain of unknown function (DUF4618) LPP PF04728.13 KFP07983.1 - 6.1 7.3 10.5 17 5.9 0.1 3.6 3 0 0 3 3 3 0 Lipoprotein leucine-zipper GIT_CC PF16559.5 KFP07983.1 - 7.3 6.5 26.2 2.1 8.3 0.7 4.7 4 1 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Baculo_IE-1 PF05290.11 KFP07983.1 - 7.8 6.4 8.8 9.1 6.2 0.6 3.1 3 1 0 3 3 3 0 Baculovirus immediate-early protein (IE-0) Sin_N PF04801.13 KFP07984.1 - 1e-156 522.5 3.0 1e-156 522.5 3.0 1.9 2 0 0 2 2 2 1 Sin-like protein conserved region ATG13 PF10033.9 KFP07984.1 - 0.62 9.7 3.6 0.16 11.6 0.2 1.7 2 0 0 2 2 2 0 Autophagy-related protein 13 Alpha_kinase PF02816.18 KFP07985.1 - 2.5e-61 207.0 0.1 4.1e-61 206.3 0.1 1.4 1 0 0 1 1 1 1 Alpha-kinase family Sel1 PF08238.12 KFP07985.1 - 7.8e-08 32.7 8.9 0.38 11.5 0.1 5.2 5 0 0 5 5 5 3 Sel1 repeat 3Beta_HSD PF01073.19 KFP07986.1 - 4.4e-66 222.8 0.0 5.4e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFP07986.1 - 1.6e-26 93.2 0.0 2.1e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFP07986.1 - 3.2e-13 49.8 0.0 1.2e-12 47.9 0.0 1.8 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KFP07986.1 - 2.2e-09 36.8 0.0 2.9e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KFP07986.1 - 6.9e-08 32.0 0.5 3.3e-07 29.7 0.5 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KFP07986.1 - 2e-07 31.1 0.0 2.5e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KFP07986.1 - 6.4e-07 28.8 0.0 1.7e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KFP07986.1 - 3.8e-05 23.4 0.0 6.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KFP07986.1 - 0.0049 16.3 0.0 0.0072 15.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 KFP07987.1 - 8e-60 202.2 0.0 9.7e-60 201.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFP07987.1 - 1.4e-24 86.9 0.0 1.7e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFP07987.1 - 1.9e-11 43.9 0.0 9.1e-11 41.7 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KFP07987.1 - 3.5e-10 39.5 0.0 6.1e-10 38.7 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KFP07987.1 - 6.7e-07 28.7 0.0 3.6e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KFP07987.1 - 4.7e-06 26.6 0.0 6.8e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KFP07987.1 - 1.2e-05 24.5 0.0 1.8e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 KFP07987.1 - 0.098 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Atthog PF18800.1 KFP07988.1 - 3.2e-62 208.6 4.1 3.5e-62 208.4 4.1 1.0 1 0 0 1 1 1 1 Attenuator of Hedgehog 7tm_3 PF00003.22 KFP07988.1 - 5.1e-05 23.1 4.7 5.6e-05 23.0 4.7 1.0 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Cyt_bd_oxida_I PF01654.17 KFP07988.1 - 0.00017 20.3 4.0 0.00021 20.1 4.0 1.1 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I LtrA PF06772.11 KFP07988.1 - 0.0015 17.8 0.5 0.0018 17.6 0.5 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF423 PF04241.15 KFP07988.1 - 0.057 13.6 0.9 0.057 13.6 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF423) DUF998 PF06197.13 KFP07988.1 - 0.073 12.7 7.1 0.2 11.2 7.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF998) L_HMGIC_fpl PF10242.9 KFP07988.1 - 0.094 12.9 5.8 0.15 12.2 5.5 1.6 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein TctB PF07331.11 KFP07988.1 - 0.28 11.5 10.9 0.95 9.7 10.9 1.8 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF3784 PF12650.7 KFP07988.1 - 0.9 9.8 11.7 2.6 8.3 11.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3784) DUF2721 PF11026.8 KFP07988.1 - 1.5 8.7 10.3 1.7 8.6 4.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF456 PF04306.13 KFP07988.1 - 2.4 8.4 11.4 16 5.7 11.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF456) Peptidase_M16 PF00675.20 KFP07989.1 - 1e-30 106.7 0.0 1.7e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFP07989.1 - 5.8e-21 75.3 0.0 1.4e-20 74.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase M16 inactive domain OCD_Mu_crystall PF02423.15 KFP07990.1 - 5.7e-92 308.0 0.2 6.3e-92 307.9 0.2 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KFP07990.1 - 4.3e-08 33.3 0.0 6.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KFP07990.1 - 0.00024 21.6 0.1 0.00061 20.3 0.0 1.7 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KFP07990.1 - 0.00047 20.3 0.7 0.0035 17.5 0.6 2.4 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase OTCace PF00185.24 KFP07990.1 - 0.15 12.1 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Ank_2 PF12796.7 KFP07991.1 - 1.7e-17 63.8 0.3 1.3e-14 54.5 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP07991.1 - 2.7e-17 62.6 4.0 1.4e-07 31.6 0.2 3.9 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP07991.1 - 2.3e-16 59.9 0.7 6.5e-06 26.6 0.2 3.5 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KFP07991.1 - 8.7e-11 41.8 1.5 5.4e-08 32.9 0.4 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 KFP07991.1 - 6.8e-10 38.3 0.5 6e-05 23.1 0.2 4.3 4 0 0 4 4 4 1 Ankyrin repeat SAM_1 PF00536.30 KFP07991.1 - 4.3e-07 30.3 0.0 9.6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ribosomal_S18 PF01084.20 KFP07991.1 - 0.006 16.8 0.4 0.014 15.6 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 SAM_2 PF07647.17 KFP07991.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Zona_pellucida PF00100.23 KFP07992.1 - 3.1e-47 161.5 0.0 2.5e-46 158.6 0.0 2.2 2 1 0 2 2 2 1 Zona pellucida-like domain Promethin PF16015.5 KFP07993.1 - 7.3e-23 80.5 12.6 8.6e-23 80.3 12.6 1.1 1 0 0 1 1 1 1 Promethin DUF2207 PF09972.9 KFP07993.1 - 0.0064 15.3 1.2 0.0086 14.9 1.2 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) CcmH PF03918.14 KFP07993.1 - 0.0072 15.6 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome C biogenesis protein DUF2070 PF09843.9 KFP07993.1 - 0.076 11.3 3.8 0.08 11.2 3.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) AAA_6 PF12774.7 KFP07994.1 - 1.7e-163 543.2 0.0 3.9e-162 538.8 0.0 3.0 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KFP07994.1 - 2.3e-144 481.4 12.3 2.3e-144 481.4 12.3 4.0 4 1 2 6 6 5 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 KFP07994.1 - 7.4e-124 412.9 0.0 2.5e-123 411.2 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 KFP07994.1 - 1.6e-106 355.4 0.9 5.6e-106 353.6 0.9 2.1 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KFP07994.1 - 1.9e-87 292.0 4.5 1.9e-87 292.0 4.5 3.3 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 KFP07994.1 - 4.6e-80 267.4 0.2 2.6e-77 258.4 0.0 3.6 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KFP07994.1 - 2.1e-64 216.2 0.0 6.5e-64 214.7 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KFP07994.1 - 2.3e-50 171.6 1.8 5e-50 170.5 1.8 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KFP07994.1 - 1.8e-49 166.8 0.2 8.7e-46 154.9 0.0 3.6 3 0 0 3 3 3 2 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 KFP07994.1 - 1.3e-36 125.5 0.2 6.8e-36 123.2 0.2 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KFP07994.1 - 4.3e-23 81.8 0.0 2.5e-06 27.5 0.0 6.7 6 1 0 6 6 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KFP07994.1 - 7.6e-22 77.4 0.2 5.3e-21 74.7 0.2 2.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KFP07994.1 - 1.2e-06 28.8 0.6 0.05 13.9 0.0 5.2 5 0 0 5 5 5 1 AAA domain AAA PF00004.29 KFP07994.1 - 4.1e-06 27.2 1.2 0.39 11.1 0.0 4.6 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFP07994.1 - 2.7e-05 24.6 0.0 0.084 13.3 0.0 3.4 2 0 0 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.22 KFP07994.1 - 8.2e-05 23.0 0.0 1.2 9.6 0.0 4.3 3 0 0 3 3 3 2 RNA helicase Spc7 PF08317.11 KFP07994.1 - 0.00059 18.8 1.5 0.00059 18.8 1.5 5.1 5 0 0 5 5 4 2 Spc7 kinetochore protein T2SSE PF00437.20 KFP07994.1 - 0.0013 17.8 1.2 0.0042 16.2 0.0 2.4 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_18 PF13238.6 KFP07994.1 - 0.024 15.2 0.1 1.6 9.3 0.0 3.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KFP07994.1 - 0.06 13.1 0.8 16 5.1 0.0 3.8 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 KFP07994.1 - 0.08 12.3 0.3 12 5.2 0.0 3.5 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KFP07994.1 - 0.1 12.3 0.1 0.54 9.9 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.6 KFP07994.1 - 0.16 11.7 0.4 2.9 7.6 0.2 2.5 2 0 0 2 2 2 0 AAA domain UCH PF00443.29 KFP07994.1 - 0.2 11.1 4.0 0.11 12.0 0.9 2.1 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Exonuc_VII_L PF02601.15 KFP07994.1 - 5.8 6.4 25.4 1.4 8.4 0.6 4.3 3 1 1 4 4 4 0 Exonuclease VII, large subunit MerR-DNA-bind PF09278.11 KFP07994.1 - 7.2 7.2 8.3 29 5.3 3.7 3.2 2 0 0 2 2 2 0 MerR, DNA binding Complex1_LYR PF05347.15 KFP07995.1 - 8.9e-15 54.5 0.3 1.4e-14 53.9 0.3 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFP07995.1 - 0.001 19.8 1.1 0.0021 18.8 1.1 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Cullin_binding PF03556.15 KFP07996.1 - 1.5e-33 115.8 0.4 2.5e-33 115.1 0.4 1.4 1 0 0 1 1 1 1 Cullin binding RRM_1 PF00076.22 KFP07997.1 - 8.7e-18 63.9 0.0 4.4e-10 39.2 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 KFP07997.1 - 1.4e-06 28.9 0.1 5.3e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 Exonuclease Na_H_antiport_3 PF07399.11 KFP07997.1 - 0.079 11.8 0.3 0.12 11.2 0.3 1.2 1 0 0 1 1 1 0 Putative Na+/H+ antiporter MutS_III PF05192.18 KFP07997.1 - 0.12 12.6 0.8 0.49 10.6 0.1 2.3 3 0 0 3 3 3 0 MutS domain III EloA-BP1 PF15870.5 KFP07997.1 - 0.18 12.0 0.8 0.61 10.3 0.0 2.2 2 0 0 2 2 2 0 ElonginA binding-protein 1 RNase_T PF00929.24 KFP07998.1 - 9.9e-22 78.2 0.0 1.4e-21 77.7 0.0 1.2 1 1 0 1 1 1 1 Exonuclease AMP-binding PF00501.28 KFP07999.1 - 2.9e-64 217.2 0.0 3.6e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFP07999.1 - 7.5e-25 87.7 1.9 1.4e-24 86.9 1.9 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SRI PF08236.11 KFP07999.1 - 0.0049 17.0 1.7 0.014 15.6 1.7 1.8 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain THUMP PF02926.17 KFP08000.1 - 9.4e-24 84.2 0.4 2e-23 83.1 0.2 1.6 1 1 0 1 1 1 1 THUMP domain VHL_C PF17211.3 KFP08000.1 - 0.05 13.6 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 VHL box domain RNase_P_Rpp14 PF01900.19 KFP08000.1 - 0.13 12.6 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 Rpp14/Pop5 family AMP-binding PF00501.28 KFP08001.1 - 9.2e-75 251.8 0.0 1.2e-74 251.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFP08001.1 - 1.6e-24 86.7 0.8 3.1e-24 85.7 0.8 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KFP08002.1 - 5.2e-84 282.3 0.0 6.8e-84 281.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFP08002.1 - 2.9e-24 85.8 1.4 5.8e-24 84.9 1.4 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 7tm_1 PF00001.21 KFP08003.1 - 6.3e-21 74.9 22.6 8e-21 74.5 22.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP08003.1 - 9.2e-09 35.3 23.6 3.5e-08 33.4 23.6 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx SMAP PF15477.6 KFP08004.1 - 6.7e-15 55.8 2.9 6.7e-15 55.8 2.9 1.9 2 0 0 2 2 2 1 Small acidic protein family CALM_bind PF16025.5 KFP08005.1 - 6.4e-24 84.2 9.4 8.6e-22 77.4 2.4 5.2 5 1 1 6 6 6 2 Calcium-dependent calmodulin binding Guanylate_cyc_2 PF09778.9 KFP08005.1 - 1.7 8.0 3.9 0.67 9.3 0.3 2.1 3 0 0 3 3 3 0 Guanylylate cyclase GDPD PF03009.17 KFP08006.1 - 1.2e-22 80.9 0.0 3.8e-22 79.3 0.0 1.7 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family TMC PF07810.13 KFP08007.1 - 5.4e-38 130.0 1.6 5.4e-38 130.0 1.6 3.4 3 1 1 4 4 4 1 TMC domain FANCI_S2 PF14676.6 KFP08007.1 - 0.014 15.7 0.2 0.047 14.0 0.2 1.8 1 0 0 1 1 1 0 FANCI solenoid 2 Sof1 PF04158.14 KFP08007.1 - 0.15 12.4 1.8 0.33 11.2 1.8 1.5 1 0 0 1 1 1 0 Sof1-like domain YebO PF13974.6 KFP08007.1 - 0.55 10.3 3.7 1.5 8.9 0.3 3.1 3 0 0 3 3 3 0 YebO-like protein DUF2681 PF10883.8 KFP08007.1 - 8.4 6.9 14.7 1 9.8 0.2 5.0 6 0 0 6 6 6 0 Protein of unknown function (DUF2681) TMC PF07810.13 KFP08009.1 - 9.1e-47 158.2 2.2 9.1e-47 158.2 2.2 3.4 4 0 0 4 4 4 1 TMC domain COQ7 PF03232.13 KFP08010.1 - 3e-76 255.0 0.0 3.3e-76 254.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 KFP08010.1 - 0.003 17.9 0.1 0.022 15.1 0.1 2.0 1 1 1 2 2 2 1 Rubrerythrin Muraidase PF11860.8 KFP08010.1 - 0.07 13.4 0.0 0.81 9.9 0.0 2.1 2 1 0 2 2 2 0 N-acetylmuramidase C2 PF00168.30 KFP08011.1 - 1.1e-42 144.5 0.1 1.4e-21 76.7 0.0 2.2 2 0 0 2 2 2 2 C2 domain Lectin_C PF00059.21 KFP08012.1 - 5e-19 69.0 0.2 6.2e-19 68.7 0.2 1.1 1 0 0 1 1 1 1 Lectin C-type domain SMG1 PF15785.5 KFP08013.1 - 1.2e-255 849.7 12.4 3.5e-255 848.2 9.3 2.7 2 0 0 2 2 2 1 Serine/threonine-protein kinase smg-1 PI3_PI4_kinase PF00454.27 KFP08013.1 - 1.1e-52 179.4 0.0 2.6e-52 178.1 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SMG1_N PF17229.2 KFP08013.1 - 5.2e-49 165.4 4.5 1.1e-48 164.4 4.5 1.6 1 0 0 1 1 1 1 Serine/threonine-protein kinase SMG1 N-terminal FATC PF02260.20 KFP08013.1 - 5.3e-12 45.4 0.5 2.6e-11 43.1 0.1 2.6 2 0 0 2 2 2 1 FATC domain HEAT PF02985.22 KFP08013.1 - 0.035 14.3 0.4 0.78 10.2 0.0 3.4 2 0 0 2 2 2 0 HEAT repeat HEAT_2 PF13646.6 KFP08013.1 - 0.06 13.8 0.1 11 6.4 0.0 3.6 2 0 0 2 2 2 0 HEAT repeats Reticulon PF02453.17 KFP08014.1 - 0.0026 17.7 4.1 0.0037 17.2 4.1 1.1 1 0 0 1 1 1 1 Reticulon DUF4131 PF13567.6 KFP08014.1 - 3.7 7.2 5.5 7.5 6.2 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Ribosomal_S8 PF00410.19 KFP08015.1 - 1.7e-22 79.7 0.0 2.4e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Xylo_C PF12529.8 KFP08016.1 - 3.7e-67 225.5 0.0 7.3e-67 224.5 0.0 1.5 1 0 0 1 1 1 1 Xylosyltransferase C terminal Branch PF02485.21 KFP08016.1 - 1.2e-41 142.9 3.5 1.9e-41 142.2 3.5 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme RNase_PH PF01138.21 KFP08017.1 - 5.5e-25 88.4 0.1 1e-24 87.5 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFP08017.1 - 1.8e-12 47.1 0.0 3.3e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Glycos_transf_2 PF00535.26 KFP08018.1 - 6.2e-24 84.7 0.0 7.9e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KFP08018.1 - 4.7e-08 33.2 0.0 7.4e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KFP08018.1 - 0.00076 19.0 0.0 0.001 18.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Pribosyltran PF00156.27 KFP08018.1 - 0.093 12.2 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase domain MH2 PF03166.14 KFP08019.1 - 1.4e-74 250.3 1.6 1.9e-74 249.9 1.6 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 KFP08019.1 - 1.5e-42 144.0 1.2 3.6e-42 142.8 1.2 1.6 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.9 KFP08019.1 - 0.0013 18.5 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 DUF4223 PF13978.6 KFP08019.1 - 0.02 14.8 0.5 0.044 13.8 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) SRTM1 PF15872.5 KFP08020.1 - 1.4e-52 176.1 10.7 1.6e-52 176.0 10.7 1.0 1 0 0 1 1 1 1 Serine-rich and transmembrane domain-containing protein 1 Cyclin_N PF00134.23 KFP08021.1 - 6.3e-48 161.7 0.1 1.1e-47 160.9 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP08021.1 - 2.2e-30 105.2 0.5 6.7e-30 103.6 0.2 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain DCX PF03607.17 KFP08022.1 - 4.7e-37 125.9 0.1 5.2e-23 80.9 0.0 2.5 2 0 0 2 2 2 2 Doublecortin Pkinase PF00069.25 KFP08023.1 - 1.4e-75 254.1 0.0 1.8e-75 253.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP08023.1 - 2.9e-34 118.5 0.0 3.7e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFP08023.1 - 7.7e-05 22.1 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFP08023.1 - 0.00034 20.0 0.0 0.00075 18.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFP08023.1 - 0.0016 17.3 0.4 0.004 16.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 KFP08023.1 - 0.081 12.4 0.0 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 KFP08023.1 - 0.12 11.9 0.2 0.25 10.9 0.2 1.4 1 0 0 1 1 1 0 RIO1 family RVT_1 PF00078.27 KFP08024.1 - 0.0003 20.4 0.0 0.00047 19.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mab-21 PF03281.14 KFP08025.1 - 1.8e-98 329.5 0.0 2.3e-98 329.2 0.0 1.1 1 0 0 1 1 1 1 Mab-21 protein DNA_pol3_delta2 PF13177.6 KFP08026.1 - 5.1e-10 39.4 1.0 5.7e-10 39.2 0.1 1.5 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 KFP08026.1 - 4.1e-06 27.3 0.0 8.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 KFP08026.1 - 3.4e-05 23.7 0.3 6.2e-05 22.8 0.3 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 KFP08026.1 - 0.0019 18.5 0.1 0.011 16.0 0.1 2.1 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 KFP08026.1 - 0.0048 16.8 0.1 0.0098 15.8 0.1 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KFP08026.1 - 0.0056 17.1 0.1 0.021 15.2 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 KFP08026.1 - 0.012 16.2 0.0 0.021 15.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Rep_fac_C PF08542.11 KFP08026.1 - 0.023 15.1 0.0 0.1 13.0 0.0 2.1 2 0 0 2 2 2 0 Replication factor C C-terminal domain DUF2247 PF10004.9 KFP08026.1 - 0.042 13.6 0.2 0.071 12.9 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) ATPgrasp_ST PF14397.6 KFP08026.1 - 0.051 12.8 0.1 0.13 11.5 0.1 1.6 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp START PF01852.19 KFP08027.1 - 6.4e-43 146.6 0.4 1.2e-42 145.8 0.4 1.4 1 0 0 1 1 1 1 START domain RhoGAP PF00620.27 KFP08027.1 - 6.7e-36 123.4 0.9 1.3e-35 122.5 0.9 1.5 1 0 0 1 1 1 1 RhoGAP domain Glyco_hydro_1 PF00232.18 KFP08028.1 - 1.8e-143 478.3 15.7 2.1e-73 247.3 5.3 4.0 2 2 1 3 3 3 3 Glycosyl hydrolase family 1 Cnd1 PF12717.7 KFP08029.1 - 0.0025 17.9 16.7 0.24 11.4 0.3 5.9 4 2 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFP08029.1 - 0.0039 17.3 4.1 1.6 9.2 0.0 5.8 6 0 0 6 6 6 1 HEAT repeat Hepatitis_core PF00906.20 KFP08029.1 - 0.0049 16.5 0.6 0.052 13.1 0.0 2.5 3 0 0 3 3 3 1 Hepatitis core antigen PI-TkoII_IV PF18714.1 KFP08029.1 - 0.043 13.3 0.0 0.15 11.5 0.0 1.9 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV DUF5578 PF17741.1 KFP08029.1 - 0.059 12.8 2.1 0.4 10.1 0.1 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5578) FANCI_S2 PF14676.6 KFP08029.1 - 0.13 12.6 2.5 3.4 8.0 0.5 3.5 2 1 0 2 2 2 0 FANCI solenoid 2 HEAT_EZ PF13513.6 KFP08029.1 - 0.21 12.1 2.2 1.4e+02 3.2 0.0 4.9 6 0 0 6 6 6 0 HEAT-like repeat Nipped-B_C PF12830.7 KFP08029.1 - 1.7 8.6 5.1 13 5.6 0.0 4.2 5 1 0 5 5 5 0 Sister chromatid cohesion C-terminus AAA_33 PF13671.6 KFP08030.1 - 1.3e-19 70.8 0.0 3.6e-19 69.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KFP08030.1 - 2.6e-05 23.6 0.0 6.7e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin KTI12 PF08433.10 KFP08030.1 - 0.00043 19.8 1.4 0.0011 18.5 0.0 2.3 2 1 0 2 2 2 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 KFP08030.1 - 0.0011 19.5 4.6 0.0015 19.1 0.0 3.3 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KFP08030.1 - 0.011 16.3 0.7 0.1 13.1 0.0 2.6 3 0 0 3 3 3 0 ABC transporter AAA_17 PF13207.6 KFP08030.1 - 0.039 14.4 0.1 0.14 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KFP08030.1 - 0.044 13.5 0.1 0.31 10.8 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KFP08030.1 - 0.056 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KFP08030.1 - 0.083 13.2 0.2 0.32 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain TssO PF17561.2 KFP08030.1 - 2.8 8.0 6.6 0.73 9.9 2.6 2.0 2 0 0 2 2 2 0 Type VI secretion system, TssO BRCA-2_helical PF09169.10 KFP08032.1 - 4e-90 300.5 0.0 1.1e-89 299.1 0.0 1.8 1 0 0 1 1 1 1 BRCA2, helical BRCA2 PF00634.18 KFP08032.1 - 8e-55 182.2 19.9 8.4e-11 41.4 0.2 7.4 7 0 0 7 7 7 6 BRCA2 repeat BRCA-2_OB3 PF09104.10 KFP08032.1 - 7.2e-53 178.0 0.0 2.6e-52 176.2 0.0 2.1 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 BRCA-2_OB1 PF09103.10 KFP08032.1 - 4.3e-40 136.5 0.0 1.5e-39 134.7 0.0 2.1 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Tower PF09121.10 KFP08032.1 - 6.7e-21 74.2 4.5 2.1e-20 72.6 4.5 1.9 1 0 0 1 1 1 1 Tower zf-3CxxC PF13695.6 KFP08033.1 - 3.3e-10 40.3 18.1 4.3e-10 39.9 18.1 1.2 1 0 0 1 1 1 1 Zinc-binding domain zf-3CxxC_2 PF17180.4 KFP08033.1 - 2.8e-05 24.8 26.2 0.00017 22.3 26.2 2.4 1 1 0 1 1 1 1 Zinc-binding domain HypA PF01155.19 KFP08033.1 - 3.9 7.5 21.0 4 7.5 7.4 3.0 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA dUTPase PF00692.19 KFP08034.1 - 1.5e-12 47.4 0.0 2.3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 dUTPase zf-C2H2 PF00096.26 KFP08035.1 - 2.6e-11 43.3 7.2 6.1e-07 29.6 0.3 2.3 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP08035.1 - 4.6e-08 33.1 11.8 4.4e-06 26.9 0.3 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP08035.1 - 5e-07 30.0 6.0 0.0007 20.2 0.5 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-LYAR PF08790.11 KFP08035.1 - 0.0026 17.6 4.6 0.052 13.5 0.4 2.2 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 KFP08035.1 - 0.0033 17.0 0.8 0.31 10.7 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 KFP08035.1 - 0.0034 17.7 4.4 0.017 15.5 0.2 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP08035.1 - 0.0072 16.6 1.3 0.29 11.5 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding MRP-S23 PF10484.9 KFP08035.1 - 0.031 14.5 0.0 0.051 13.8 0.0 1.4 1 1 1 2 2 2 0 Mitochondrial ribosomal protein S23 Zn-ribbon_8 PF09723.10 KFP08035.1 - 0.039 14.1 1.4 1.7 8.9 0.2 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 KFP08035.1 - 0.085 12.6 4.8 0.13 12.0 0.5 2.5 2 1 0 2 2 2 0 zinc-finger C2H2-type XPA_N PF01286.18 KFP08035.1 - 0.34 11.0 1.7 3.2 7.9 0.1 2.2 2 0 0 2 2 2 0 XPA protein N-terminal zf-C2H2_6 PF13912.6 KFP08035.1 - 2.3 8.3 6.4 9.6 6.3 0.2 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger RHD_DNA_bind PF00554.22 KFP08036.1 - 9.5e-71 237.2 0.0 1.9e-70 236.2 0.0 1.5 1 0 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.5 KFP08036.1 - 3.1e-40 136.3 0.0 6.3e-40 135.4 0.0 1.5 1 0 0 1 1 1 1 Rel homology dimerisation domain Ank_2 PF12796.7 KFP08036.1 - 9.3e-29 99.9 12.8 3.9e-10 40.2 0.2 4.3 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP08036.1 - 1.2e-22 79.9 3.7 3.5e-07 30.6 0.0 5.2 3 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP08036.1 - 1.2e-21 76.5 5.8 2.2e-07 31.0 0.1 5.6 3 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KFP08036.1 - 1.6e-20 72.5 12.0 0.00026 21.3 0.0 7.5 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 KFP08036.1 - 3.5e-20 70.0 6.2 0.021 15.4 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Death PF00531.22 KFP08036.1 - 1.3e-12 47.7 0.0 2.9e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Death domain Ig_mannosidase PF17753.1 KFP08037.1 - 7.1e-21 73.8 0.1 2e-20 72.3 0.1 1.9 1 0 0 1 1 1 1 Ig-fold domain Mannosidase_ig PF17786.1 KFP08037.1 - 4.2e-10 40.1 0.0 1.2e-09 38.6 0.0 1.9 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2_C PF02836.17 KFP08037.1 - 1e-07 31.4 0.2 5.2e-07 29.1 0.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KFP08037.1 - 6e-05 23.0 0.3 0.00016 21.6 0.3 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain UQ_con PF00179.26 KFP08038.1 - 1.4e-48 164.1 0.0 1.5e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFP08038.1 - 0.012 15.9 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 KFP08038.1 - 0.021 14.5 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 KFP08038.1 - 0.061 13.2 0.1 0.099 12.5 0.1 1.3 1 1 0 1 1 1 0 UEV domain zf-CDGSH PF09360.10 KFP08039.1 - 4.3e-10 39.7 0.2 7.4e-10 38.9 0.2 1.4 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type MitoNEET_N PF10660.9 KFP08039.1 - 2.7e-08 33.7 0.0 3.8e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus Pkinase PF00069.25 KFP08040.1 - 4.6e-34 118.0 0.0 7.7e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP08040.1 - 1.7e-31 109.5 0.0 2.8e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Activin_recp PF01064.23 KFP08040.1 - 4.3e-06 27.7 12.0 4.3e-06 27.7 12.0 2.2 2 0 0 2 2 2 1 Activin types I and II receptor domain Pkinase_fungal PF17667.1 KFP08040.1 - 2.2e-05 23.4 0.0 3.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KFP08040.1 - 0.034 13.8 0.0 0.22 11.1 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFP08040.1 - 0.053 13.4 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PWWP PF00855.17 KFP08041.1 - 0.00013 22.3 0.0 0.00038 20.8 0.0 1.8 1 0 0 1 1 1 1 PWWP domain MBD PF01429.19 KFP08041.1 - 0.04 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyl-CpG binding domain Kinesin PF00225.23 KFP08042.1 - 9.7e-111 369.9 0.3 9.7e-111 369.9 0.3 2.5 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KFP08042.1 - 1e-22 80.7 0.0 1e-22 80.7 0.0 3.7 3 1 1 4 4 4 1 Microtubule binding DASH_Dam1 PF08653.10 KFP08042.1 - 0.5 10.2 12.2 3.3 7.6 0.6 4.7 3 0 0 3 3 3 0 DASH complex subunit Dam1 PTSIIB_sorb PF03830.15 KFP08042.1 - 1.4 9.1 8.4 1.8 8.8 0.1 3.9 3 0 0 3 3 3 0 PTS system sorbose subfamily IIB component UPAR_LY6_2 PF16975.5 KFP08043.1 - 1.4e-53 179.6 15.3 1.6e-53 179.4 15.3 1.1 1 0 0 1 1 1 1 Ly6/PLAUR domain-containing protein 6, Lypd6 RVT_1 PF00078.27 KFP08044.1 - 0.002 17.7 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.11 KFP08044.1 - 0.26 11.0 0.6 0.43 10.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) UPAR_LY6_2 PF16975.5 KFP08045.1 - 5.2e-52 174.5 11.7 6.1e-52 174.3 11.7 1.1 1 0 0 1 1 1 1 Ly6/PLAUR domain-containing protein 6, Lypd6 MMADHC PF10229.9 KFP08046.1 - 4.8e-132 439.7 0.0 5.5e-132 439.5 0.0 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein Yae1_N PF09811.9 KFP08047.1 - 0.00015 21.4 52.6 1.8e+04 -27.5 52.6 4.5 1 1 0 1 1 1 0 Essential protein Yae1, N terminal IFRD_C PF04836.12 KFP08047.1 - 0.14 12.7 49.3 1.8e+04 -37.7 49.3 8.8 1 1 0 1 1 1 0 Interferon-related protein conserved region Ras PF00071.22 KFP08048.1 - 6.9e-43 146.1 0.0 9.1e-43 145.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP08048.1 - 6.6e-19 68.3 0.0 1.2e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP08048.1 - 7.7e-07 28.7 0.0 1.1e-06 28.2 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFP08048.1 - 0.019 14.4 0.0 0.055 12.9 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KFP08048.1 - 0.023 14.1 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein PduV-EutP PF10662.9 KFP08048.1 - 0.098 12.4 0.0 0.71 9.6 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 KFP08048.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFP08048.1 - 0.15 12.4 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NID PF07292.13 KFP08049.1 - 4.4e-13 49.7 0.7 8.8e-08 32.7 0.0 2.9 3 0 0 3 3 3 2 Nmi/IFP 35 domain (NID) RRM_1 PF00076.22 KFP08049.1 - 0.012 15.5 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFP08049.1 - 0.15 12.1 0.1 1.4 9.0 0.1 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif NID PF07292.13 KFP08050.1 - 1.9e-55 185.4 0.0 4.6e-28 97.7 0.0 2.0 2 0 0 2 2 2 2 Nmi/IFP 35 domain (NID) CUB PF00431.20 KFP08051.1 - 1.1e-36 125.5 0.2 2e-36 124.7 0.2 1.4 1 0 0 1 1 1 1 CUB domain Xlink PF00193.17 KFP08051.1 - 7.1e-30 103.3 0.4 1.1e-29 102.6 0.4 1.3 1 0 0 1 1 1 1 Extracellular link domain Rif1_N PF12231.8 KFP08052.1 - 1.2e-73 248.3 5.7 1.2e-73 248.3 5.7 2.1 3 0 0 3 3 3 1 Rap1-interacting factor 1 N terminal Arf PF00025.21 KFP08053.1 - 1.9e-64 216.3 0.9 2.1e-64 216.2 0.9 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFP08053.1 - 2.4e-15 56.8 0.3 3.2e-15 56.4 0.3 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP08053.1 - 3.3e-14 52.8 0.4 3.6e-14 52.7 0.4 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFP08053.1 - 3.5e-12 46.1 0.2 4.3e-12 45.8 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFP08053.1 - 1.1e-08 34.7 1.5 1.6e-06 27.5 0.6 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KFP08053.1 - 2.7e-07 30.6 0.1 3.8e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFP08053.1 - 5.8e-07 29.1 0.4 6.9e-07 28.9 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFP08053.1 - 0.0031 17.1 0.4 0.016 14.8 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 KFP08053.1 - 0.021 14.8 0.2 0.079 13.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KFP08053.1 - 0.037 13.5 0.9 0.2 11.2 0.8 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B TPM_phosphatase PF04536.14 KFP08053.1 - 0.072 13.3 0.2 0.16 12.1 0.1 1.7 1 1 1 2 2 2 0 TPM domain VHS PF00790.19 KFP08054.1 - 6.2e-38 129.8 0.8 4.8e-37 127.0 0.1 2.3 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.28 KFP08054.1 - 7.6e-19 67.1 0.1 1.5e-18 66.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP08054.1 - 4e-12 45.8 0.1 7.8e-12 44.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP08054.1 - 4.6e-12 45.4 0.0 8.7e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.20 KFP08054.1 - 1.9e-05 24.3 2.0 4.5e-05 23.1 2.0 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif SH3_10 PF17902.1 KFP08054.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 SH3 domain TED_complement PF07678.14 KFP08055.1 - 9.4e-107 356.6 0.6 1.6e-106 355.9 0.6 1.4 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_BRD PF07703.14 KFP08055.1 - 6.9e-36 123.7 3.3 6.3e-33 114.1 0.0 3.0 3 0 0 3 3 3 2 Alpha-2-macroglobulin bait region domain A2M PF00207.22 KFP08055.1 - 1.4e-29 101.8 0.4 5.3e-29 99.9 0.1 2.2 2 0 0 2 2 2 1 Alpha-2-macroglobulin family MG3 PF17791.1 KFP08055.1 - 2.2e-26 91.9 0.7 1.2e-24 86.4 0.4 3.2 2 0 0 2 2 2 1 Macroglobulin domain MG3 A2M_recep PF07677.14 KFP08055.1 - 9.5e-25 87.1 1.0 9.5e-25 87.1 1.0 2.7 2 0 0 2 2 2 1 A-macroglobulin receptor binding domain MG2 PF01835.19 KFP08055.1 - 4.5e-21 75.1 0.1 1.4e-19 70.4 0.0 3.4 4 0 0 4 4 3 1 MG2 domain MG4 PF17789.1 KFP08055.1 - 2.5e-18 66.0 0.5 1.7e-16 60.1 0.0 3.3 3 0 0 3 3 3 1 Macroglobulin domain MG4 SQHop_cyclase_C PF13243.6 KFP08055.1 - 3.4e-06 26.4 0.1 0.0011 18.2 0.2 2.2 1 1 1 2 2 2 2 Squalene-hopene cyclase C-terminal domain SVA PF05326.11 KFP08055.1 - 0.00063 19.7 0.1 0.0019 18.2 0.1 1.8 1 0 0 1 1 1 1 Seminal vesicle autoantigen (SVA) Big_1 PF02369.16 KFP08055.1 - 0.0049 16.8 0.3 0.034 14.1 0.3 2.5 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 1) bMG3 PF11974.8 KFP08055.1 - 0.0083 16.1 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 Bacterial alpha-2-macroglobulin MG3 domain MG1 PF17790.1 KFP08055.1 - 0.014 15.8 0.4 0.19 12.2 0.0 3.1 3 0 0 3 3 3 0 Macroglobulin domain MG1 Prenyltrans PF00432.21 KFP08055.1 - 0.1 12.4 3.4 0.11 12.3 0.0 2.9 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat Big_3_5 PF16640.5 KFP08055.1 - 0.32 11.2 3.0 6.6 7.0 0.0 4.3 6 0 0 6 6 6 0 Bacterial Ig-like domain (group 3) TED_complement PF07678.14 KFP08056.1 - 2.2e-56 191.2 0.1 3e-56 190.7 0.1 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_BRD PF07703.14 KFP08056.1 - 1.9e-32 112.5 4.0 9.2e-30 103.8 0.2 3.6 4 1 0 4 4 4 2 Alpha-2-macroglobulin bait region domain A2M PF00207.22 KFP08056.1 - 5.2e-29 100.0 0.2 3.2e-28 97.4 0.0 2.5 3 0 0 3 3 3 1 Alpha-2-macroglobulin family MG3 PF17791.1 KFP08056.1 - 3.7e-25 88.0 2.5 1.3e-24 86.2 0.5 2.7 2 0 0 2 2 2 1 Macroglobulin domain MG3 MG4 PF17789.1 KFP08056.1 - 3.2e-20 72.1 0.5 2.8e-19 69.1 0.0 3.0 3 0 0 3 3 3 1 Macroglobulin domain MG4 MG2 PF01835.19 KFP08056.1 - 2e-19 69.8 0.0 1.1e-18 67.5 0.0 2.4 2 0 0 2 2 2 1 MG2 domain SVA PF05326.11 KFP08056.1 - 0.0022 18.0 0.3 0.0085 16.1 0.0 2.2 2 0 0 2 2 2 1 Seminal vesicle autoantigen (SVA) MG1 PF17790.1 KFP08056.1 - 0.0094 16.4 0.1 0.049 14.0 0.0 2.3 2 0 0 2 2 2 1 Macroglobulin domain MG1 Big_1 PF02369.16 KFP08056.1 - 0.017 15.1 3.1 0.031 14.3 0.2 3.0 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) DUF1433 PF07252.11 KFP08056.1 - 0.1 12.9 0.1 0.27 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1433) TED_complement PF07678.14 KFP08057.1 - 4.4e-69 232.9 0.0 6.6e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_BRD PF07703.14 KFP08057.1 - 7.1e-33 113.9 0.1 2.7e-29 102.3 0.0 2.9 2 0 0 2 2 2 2 Alpha-2-macroglobulin bait region domain A2M PF00207.22 KFP08057.1 - 8.9e-31 105.6 0.7 2.2e-30 104.3 0.2 2.1 2 0 0 2 2 2 1 Alpha-2-macroglobulin family MG3 PF17791.1 KFP08057.1 - 4.7e-25 87.7 0.4 1.6e-23 82.8 0.2 2.9 2 0 0 2 2 2 1 Macroglobulin domain MG3 MG4 PF17789.1 KFP08057.1 - 2.2e-24 85.4 0.0 1.5e-23 82.7 0.0 2.6 2 0 0 2 2 2 1 Macroglobulin domain MG4 MG2 PF01835.19 KFP08057.1 - 2.3e-15 56.8 0.0 9.3e-15 54.9 0.0 2.1 1 0 0 1 1 1 1 MG2 domain Big_1 PF02369.16 KFP08057.1 - 0.001 19.0 0.1 0.0073 16.3 0.1 2.5 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 1) SVA PF05326.11 KFP08057.1 - 0.0026 17.8 1.3 0.0066 16.5 0.0 2.3 3 0 0 3 3 3 1 Seminal vesicle autoantigen (SVA) CarboxypepD_reg PF13620.6 KFP08057.1 - 0.012 15.9 0.5 0.31 11.4 0.1 2.8 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain DUF4228 PF14009.6 KFP08057.1 - 0.059 13.8 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) PHC2_SAM_assoc PF16616.5 KFP08058.1 - 6e-28 98.1 5.7 6e-28 98.1 5.7 6.2 5 2 1 6 6 6 1 Unstructured region on Polyhomeotic-like protein 1 and 2 SAM_1 PF00536.30 KFP08058.1 - 1.3e-16 60.8 0.0 2.7e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP08058.1 - 6.3e-10 39.0 0.0 1.2e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFP08058.1 - 0.0043 17.0 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain zf-FCS PF06467.14 KFP08058.1 - 0.2 11.6 4.4 0.84 9.6 4.4 2.1 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-CGNR PF11706.8 KFP08058.1 - 0.46 10.4 4.2 1 9.3 4.2 1.5 1 0 0 1 1 1 0 CGNR zinc finger TED_complement PF07678.14 KFP08059.1 - 3.7e-57 193.7 0.0 5e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M PF00207.22 KFP08059.1 - 2.8e-25 88.0 0.2 9.7e-25 86.3 0.1 2.1 2 0 0 2 2 2 1 Alpha-2-macroglobulin family A2M_BRD PF07703.14 KFP08059.1 - 1e-18 68.0 0.0 2.8e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 Alpha-2-macroglobulin bait region domain SVA PF05326.11 KFP08059.1 - 4.2e-10 39.7 0.8 1e-09 38.5 0.8 1.6 1 0 0 1 1 1 1 Seminal vesicle autoantigen (SVA) MAGP PF05507.11 KFP08060.1 - 3.7e-29 101.8 9.6 3.7e-29 101.8 9.6 1.4 2 0 0 2 2 2 1 Microfibril-associated glycoprotein (MAGP) SVWC PF15430.6 KFP08060.1 - 0.035 14.4 4.1 0.11 12.7 0.5 2.4 1 1 1 2 2 2 0 Single domain von Willebrand factor type C APOBEC2 PF18772.1 KFP08061.1 - 1.1e-69 234.0 1.4 1.2e-69 233.8 1.4 1.0 1 0 0 1 1 1 1 APOBEC2 NAD1 PF18778.1 KFP08061.1 - 3.3e-68 229.2 1.2 3.8e-68 229.0 1.2 1.0 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 KFP08061.1 - 1.5e-60 204.1 0.7 1.7e-60 204.0 0.7 1.0 1 0 0 1 1 1 1 APOBEC-like N-terminal domain NAD2 PF18782.1 KFP08061.1 - 1.4e-58 197.9 4.5 1.6e-58 197.7 4.5 1.0 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 SNAD4 PF18750.1 KFP08061.1 - 6.3e-37 126.2 0.1 8.7e-37 125.7 0.1 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 KFP08061.1 - 2.4e-35 121.6 0.2 3.1e-35 121.3 0.2 1.1 1 0 0 1 1 1 1 APOBEC3 APOBEC_C PF05240.14 KFP08061.1 - 2.3e-29 101.2 0.1 3.9e-29 100.4 0.1 1.4 1 0 0 1 1 1 1 APOBEC-like C-terminal domain APOBEC4_like PF18774.1 KFP08061.1 - 2.1e-25 89.2 0.2 2.7e-25 88.8 0.2 1.2 1 0 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase APOBEC4 PF18775.1 KFP08061.1 - 2.6e-21 75.5 0.0 4.4e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 APOBEC4 APOBEC1 PF18769.1 KFP08061.1 - 3e-19 69.1 0.0 4.5e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 APOBEC1 DUF2599 PF10783.9 KFP08061.1 - 0.055 14.1 0.1 0.43 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2599) Toxin-deaminase PF14424.6 KFP08061.1 - 0.072 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases RcbX PF02341.15 KFP08061.1 - 0.091 13.0 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 RbcX protein APOBEC4_like PF18774.1 KFP08062.1 - 4.9e-50 168.9 0.0 5.7e-50 168.7 0.0 1.0 1 0 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase APOBEC1 PF18769.1 KFP08062.1 - 1.4e-44 150.4 0.9 1.8e-44 150.1 0.9 1.1 1 0 0 1 1 1 1 APOBEC1 SNAD4 PF18750.1 KFP08062.1 - 1.7e-36 124.8 0.1 2e-36 124.6 0.1 1.1 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 KFP08062.1 - 1.5e-35 122.9 0.1 1.6e-35 122.7 0.1 1.0 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 KFP08062.1 - 2.5e-29 102.5 0.0 2.8e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 APOBEC2 NAD2 PF18782.1 KFP08062.1 - 1.3e-25 90.5 0.1 1.5e-25 90.3 0.1 1.0 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC4 PF18775.1 KFP08062.1 - 5.7e-25 87.3 0.0 8.2e-25 86.8 0.0 1.2 1 0 0 1 1 1 1 APOBEC4 APOBEC_N PF08210.11 KFP08062.1 - 2.1e-24 86.4 0.0 2.3e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC3 PF18771.1 KFP08062.1 - 6.1e-23 81.5 0.1 7.2e-23 81.2 0.1 1.0 1 0 0 1 1 1 1 APOBEC3 APOBEC_C PF05240.14 KFP08062.1 - 2.5e-17 62.6 0.4 3.9e-17 62.0 0.0 1.6 2 0 0 2 2 2 1 APOBEC-like C-terminal domain AID PF18767.1 KFP08062.1 - 0.0098 15.9 0.0 0.016 15.2 0.0 1.4 1 1 0 1 1 1 1 Activation induced deaminase dCMP_cyt_deam_1 PF00383.23 KFP08062.1 - 0.062 13.2 0.0 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC4 PF18775.1 KFP08063.1 - 1.4e-24 86.0 1.8 1.5e-24 85.9 1.8 1.0 1 0 0 1 1 1 1 APOBEC4 SNAD4 PF18750.1 KFP08063.1 - 1.7e-18 66.8 2.6 1.8e-18 66.7 2.6 1.0 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 KFP08063.1 - 1.9e-17 63.9 2.9 2e-17 63.8 2.9 1.0 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC1 PF18769.1 KFP08063.1 - 3e-15 56.3 0.2 3.4e-15 56.1 0.2 1.0 1 0 0 1 1 1 1 APOBEC1 APOBEC4_like PF18774.1 KFP08063.1 - 3.5e-15 56.1 1.1 3.7e-15 56.0 1.1 1.0 1 0 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase APOBEC2 PF18772.1 KFP08063.1 - 5.1e-15 55.9 2.4 5.5e-15 55.9 2.4 1.0 1 0 0 1 1 1 1 APOBEC2 APOBEC3 PF18771.1 KFP08063.1 - 9.6e-14 51.7 1.2 1e-13 51.6 1.2 1.0 1 0 0 1 1 1 1 APOBEC3 NAD2 PF18782.1 KFP08063.1 - 3.7e-13 50.0 2.2 4e-13 49.9 2.2 1.0 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC_N PF08210.11 KFP08063.1 - 2.9e-12 46.8 2.4 3.1e-12 46.8 2.4 1.0 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC_C PF05240.14 KFP08063.1 - 0.00015 21.7 0.0 0.00018 21.4 0.0 1.2 1 0 0 1 1 1 1 APOBEC-like C-terminal domain Homeodomain PF00046.29 KFP08064.1 - 4.8e-21 74.3 5.6 9.8e-21 73.4 5.6 1.5 1 0 0 1 1 1 1 Homeodomain Pro-kuma_activ PF09286.11 KFP08064.1 - 0.0031 17.8 0.3 0.0074 16.6 0.3 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Homez PF11569.8 KFP08064.1 - 0.0051 16.2 0.4 0.01 15.2 0.4 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez YdaS_antitoxin PF15943.5 KFP08064.1 - 0.045 13.6 0.1 0.089 12.7 0.1 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Homeobox_KN PF05920.11 KFP08064.1 - 0.045 13.7 8.9 0.033 14.1 4.7 2.7 2 1 0 2 2 2 0 Homeobox KN domain Homeodomain PF00046.29 KFP08065.1 - 3.4e-22 78.0 5.3 5.3e-22 77.4 5.3 1.3 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 KFP08065.1 - 0.00062 19.2 0.4 0.0011 18.4 0.4 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 KFP08065.1 - 0.0018 18.1 1.5 0.0084 16.0 1.5 2.2 1 1 0 1 1 1 1 Homeobox KN domain Pro-kuma_activ PF09286.11 KFP08065.1 - 0.0063 16.8 0.1 0.0094 16.3 0.1 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Antimicrobial21 PF14861.6 KFP08065.1 - 0.012 15.3 1.3 0.022 14.4 1.3 1.4 1 0 0 1 1 1 0 Plant antimicrobial peptide YdaS_antitoxin PF15943.5 KFP08065.1 - 0.035 14.0 0.1 0.058 13.3 0.1 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_28 PF13518.6 KFP08065.1 - 0.13 12.4 0.1 0.3 11.2 0.1 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain Sugar_tr PF00083.24 KFP08066.1 - 4e-161 536.9 25.0 4.6e-161 536.7 25.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP08066.1 - 3.6e-21 75.5 47.9 1.7e-19 70.0 25.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ycf70 PF17382.2 KFP08066.1 - 0.86 10.0 2.7 13 6.2 2.4 2.4 2 0 0 2 2 2 0 Uncharacterized Ycf70-like Phage_holin_3_2 PF04550.12 KFP08066.1 - 1.9 9.1 11.8 0.4 11.3 6.8 2.5 2 0 0 2 2 2 0 Phage holin family 2 ATP_synth_reg PF14960.6 KFP08066.1 - 8.6 5.9 8.3 0.96 9.0 0.3 3.2 3 0 0 3 3 3 0 ATP synthase regulation Forkhead PF00250.18 KFP08067.1 - 5.3e-37 125.9 0.1 1.9e-36 124.2 0.1 1.9 1 0 0 1 1 1 1 Forkhead domain DUF1681 PF07933.14 KFP08068.1 - 1.6e-57 193.4 0.0 2e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Lectin_C PF00059.21 KFP08069.1 - 9.7e-11 42.4 0.5 3.4e-10 40.6 0.2 2.0 1 1 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 KFP08070.1 - 8.2e-12 45.8 0.4 1.1e-11 45.4 0.2 1.4 2 0 0 2 2 2 1 Lectin C-type domain Peptidase_M60 PF13402.6 KFP08071.1 - 1.6e-74 250.9 0.5 2.1e-74 250.5 0.5 1.1 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like M60-like_N PF17291.2 KFP08071.1 - 6.1e-24 84.0 0.0 1.4e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases LBP_M PF17385.2 KFP08071.1 - 0.0018 17.9 0.0 0.5 9.9 0.0 3.2 3 0 0 3 3 3 2 Lacto-N-biose phosphorylase central domain FKBP_C PF00254.28 KFP08072.1 - 8.4e-50 167.1 0.1 7.7e-32 109.5 0.0 2.3 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 KFP08072.1 - 9.2e-18 63.2 10.8 8.2e-09 34.9 1.8 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFP08072.1 - 3.5e-14 51.7 12.9 6.2e-06 25.9 1.2 4.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFP08072.1 - 9.3e-09 35.4 2.1 0.0042 17.6 0.0 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFP08072.1 - 5.3e-07 29.8 2.3 2.4e-05 24.5 1.2 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFP08072.1 - 1e-06 28.4 11.5 0.00038 20.4 1.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFP08072.1 - 2.4e-06 27.9 0.9 0.0021 18.5 0.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFP08072.1 - 3.3e-06 26.7 6.4 0.0011 18.6 0.1 3.3 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.6 KFP08072.1 - 8.1e-05 23.2 0.5 0.0056 17.3 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFP08072.1 - 0.00011 22.0 4.0 0.024 14.6 0.2 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat PknG_TPR PF16918.5 KFP08072.1 - 0.00019 20.3 0.5 0.00029 19.7 0.5 1.2 1 0 0 1 1 1 1 Protein kinase G tetratricopeptide repeat TPR_14 PF13428.6 KFP08072.1 - 0.00045 20.8 0.1 0.25 12.2 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFP08072.1 - 0.0015 18.5 0.3 0.0015 18.5 0.3 3.1 3 1 1 4 4 2 1 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.7 KFP08072.1 - 0.005 16.9 0.3 0.011 15.8 0.3 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_9 PF13371.6 KFP08072.1 - 0.0065 16.6 0.0 0.017 15.3 0.0 1.7 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFP08072.1 - 0.045 14.1 5.1 1.3 9.6 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP08072.1 - 0.27 11.5 8.6 1.1 9.6 2.5 3.0 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 KFP08072.1 - 0.28 10.9 4.9 0.46 10.2 3.4 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat-like domain Alkyl_sulf_dimr PF14863.6 KFP08072.1 - 0.33 11.4 4.2 5.9 7.3 0.2 2.7 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation OmpH PF03938.14 KFP08072.1 - 2.4 8.5 8.2 0.31 11.4 1.7 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Itfg2 PF15907.5 KFP08073.1 - 9.5e-158 524.5 0.0 1.1e-157 524.3 0.0 1.1 1 0 0 1 1 1 1 Integrin-alpha FG-GAP repeat-containing protein 2 BBS2_Mid PF14783.6 KFP08073.1 - 1e-11 44.8 0.4 0.0014 18.6 0.0 3.4 3 0 0 3 3 3 3 Ciliary BBSome complex subunit 2, middle region VCBS PF13517.6 KFP08073.1 - 0.0045 17.6 4.8 0.3 11.7 0.1 3.8 4 0 0 4 4 4 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KFP08073.1 - 0.16 12.1 0.5 1.2 9.4 0.1 2.6 2 0 0 2 2 2 0 FG-GAP repeat Asp_protease PF09668.10 KFP08074.1 - 9.7e-09 35.1 0.1 1.5e-08 34.5 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFP08074.1 - 0.0056 17.2 0.0 0.01 16.4 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease BORA_N PF15280.6 KFP08074.1 - 0.093 12.4 0.0 6 6.5 0.0 2.1 1 1 1 2 2 2 0 Protein aurora borealis N-terminus Asp_protease_2 PF13650.6 KFP08074.1 - 0.094 13.4 0.0 0.16 12.6 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Forkhead PF00250.18 KFP08075.1 - 1.3e-30 105.5 0.5 1.3e-30 105.5 0.5 1.8 2 0 0 2 2 2 1 Forkhead domain RHINO PF15319.6 KFP08076.1 - 3.5e-78 263.1 10.9 3.9e-78 262.9 10.9 1.0 1 0 0 1 1 1 1 RAD9, RAD1, HUS1-interacting nuclear orphan protein Tub PF01167.18 KFP08077.1 - 5.6e-94 314.4 0.0 7.9e-94 313.9 0.0 1.2 1 0 0 1 1 1 1 Tub family Tub_N PF16322.5 KFP08077.1 - 1.4e-53 182.4 12.8 1.9e-53 182.0 12.8 1.2 1 0 0 1 1 1 1 Tubby N-terminal DUF3527 PF12043.8 KFP08077.1 - 0.26 10.8 0.0 0.26 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) YBD PF17725.1 KFP08078.1 - 9.6e-96 319.6 1.5 1.2e-95 319.2 1.5 1.1 1 0 0 1 1 1 1 YAP binding domain TEA PF01285.18 KFP08078.1 - 2e-27 95.0 0.0 4.4e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 TEA/ATTS domain MSP1a PF11670.8 KFP08078.1 - 0.29 10.4 1.0 0.47 9.7 1.0 1.2 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) Tetraspanin PF00335.20 KFP08079.1 - 2.9e-45 154.7 11.9 3.2e-45 154.6 11.9 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2207 PF09972.9 KFP08079.1 - 0.047 12.5 2.7 0.077 11.7 2.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Baculo_11_kDa PF06143.11 KFP08079.1 - 0.087 12.4 0.8 0.21 11.2 0.8 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family TadF PF16964.5 KFP08079.1 - 0.096 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative tight adherence pilin protein F OppC_N PF12911.7 KFP08079.1 - 0.71 9.9 7.7 18 5.4 5.1 2.8 2 1 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Sigma_reg_N PF13800.6 KFP08079.1 - 0.83 10.0 3.1 0.54 10.6 1.3 1.6 1 1 1 2 2 2 0 Sigma factor regulator N-terminal EF-hand_7 PF13499.6 KFP08080.1 - 6.5e-10 39.3 0.2 1e-06 29.1 0.0 3.8 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP08080.1 - 3.6e-09 35.8 0.0 0.0065 16.3 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KFP08080.1 - 1.3e-08 33.8 0.0 0.0016 17.8 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFP08080.1 - 8.9e-05 22.3 0.1 0.00036 20.3 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KFP08080.1 - 0.00044 19.6 0.1 0.014 14.9 0.0 3.1 2 0 0 2 2 2 1 EF hand LMP PF04778.12 KFP08080.1 - 0.0067 16.4 11.1 0.0067 16.4 11.1 2.0 1 1 1 2 2 2 1 LMP repeated region FTCD_C PF04961.12 KFP08080.1 - 0.43 10.3 8.0 0.23 11.2 5.3 2.0 1 1 0 2 2 2 0 Formiminotransferase-cyclodeaminase RNase_J_C PF17770.1 KFP08080.1 - 1.1 10.4 6.3 0.36 11.9 1.5 2.7 3 1 0 3 3 3 0 Ribonuclease J C-terminal domain V_ATPase_I PF01496.19 KFP08080.1 - 3.1 5.6 19.7 4.4 5.1 19.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 KFP08080.1 - 5 6.4 17.0 7.6 5.8 16.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Ras PF00071.22 KFP08081.1 - 1.2e-43 148.5 0.1 1.3e-43 148.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP08081.1 - 9.5e-34 116.2 0.2 1.1e-33 116.0 0.2 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP08081.1 - 4e-17 62.2 0.1 4.7e-17 62.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP08081.1 - 1.1e-10 41.6 0.1 1.2e-10 41.4 0.1 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFP08081.1 - 1.2e-06 28.1 0.0 1.4e-06 27.9 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFP08081.1 - 4.8e-05 22.9 0.0 6.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KFP08081.1 - 0.00024 20.7 0.1 0.00073 19.1 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 KFP08081.1 - 0.0098 16.1 0.0 0.01 16.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KFP08081.1 - 0.013 15.4 0.0 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase FeoB_N PF02421.18 KFP08081.1 - 0.015 14.9 0.1 0.018 14.6 0.1 1.4 1 1 0 1 1 1 0 Ferrous iron transport protein B G-alpha PF00503.20 KFP08081.1 - 0.027 13.7 0.9 4.3 6.4 0.0 2.4 1 1 1 2 2 2 0 G-protein alpha subunit Dynamin_N PF00350.23 KFP08081.1 - 0.031 14.3 0.0 0.097 12.7 0.0 1.6 1 1 1 2 2 2 0 Dynamin family Septin PF00735.18 KFP08081.1 - 0.048 12.9 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 Septin AAA PF00004.29 KFP08081.1 - 0.063 13.7 0.0 0.1 13.0 0.0 1.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 KFP08081.1 - 0.063 13.0 0.1 2.2 8.1 0.0 2.1 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 KFP08081.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein PrmA PF06325.13 KFP08082.1 - 2.8e-09 36.8 0.0 4.6e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KFP08082.1 - 2.1e-08 34.7 0.0 4.3e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP08082.1 - 6.5e-07 29.9 0.0 1.5e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP08082.1 - 0.0002 21.2 0.1 0.00044 20.1 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP08082.1 - 0.00024 21.0 0.0 0.00041 20.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KFP08082.1 - 0.0011 18.5 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.14 KFP08082.1 - 0.0016 18.0 0.1 0.0027 17.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 KFP08082.1 - 0.0041 16.1 0.0 0.0058 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 KFP08082.1 - 0.0043 17.8 0.0 0.0074 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFP08082.1 - 0.012 15.3 0.2 0.034 13.9 0.1 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 KFP08082.1 - 0.023 14.0 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 KFP08082.1 - 0.025 14.3 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_18 PF12847.7 KFP08082.1 - 0.041 13.8 0.1 0.071 13.0 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain PRMT5_C PF17286.2 KFP08082.1 - 0.077 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 PRMT5 oligomerisation domain PRMT5 PF05185.16 KFP08082.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.6 KFP08082.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RasGAP PF00616.19 KFP08085.1 - 2.2e-29 102.7 0.9 2.2e-19 70.0 0.1 2.4 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KFP08085.1 - 8.6e-13 48.5 0.1 3e-12 46.7 0.1 1.9 2 0 0 2 2 2 1 C2 domain BTB PF00651.31 KFP08086.1 - 1.4e-24 86.4 0.5 4.3e-24 84.9 0.5 1.9 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFP08086.1 - 5.5e-16 58.2 50.9 1.9e-06 28.0 7.9 7.5 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP08086.1 - 2.1e-09 37.4 64.8 0.014 16.2 0.8 7.0 7 0 0 7 7 6 5 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP08086.1 - 1.1e-08 35.1 58.8 0.031 14.7 0.3 6.6 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-met PF12874.7 KFP08086.1 - 1.4e-06 28.5 6.0 0.00023 21.4 1.1 6.6 7 0 0 7 7 6 2 Zinc-finger of C2H2 type GAGA PF09237.11 KFP08086.1 - 0.0019 18.0 1.1 2.8 7.8 0.0 3.7 3 0 0 3 3 3 1 GAGA factor zf-C2H2_jaz PF12171.8 KFP08086.1 - 0.0022 18.2 0.5 0.0022 18.2 0.5 6.7 6 0 0 6 6 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP08086.1 - 0.036 14.1 0.5 0.036 14.1 0.5 6.5 6 1 0 6 6 6 0 C2H2-type zinc finger zinc_ribbon_15 PF17032.5 KFP08086.1 - 0.47 11.2 21.3 6.3 7.6 3.2 3.8 2 1 1 3 3 3 0 zinc-ribbon family zf-AD PF07776.15 KFP08086.1 - 1.4 9.2 16.0 1.2 9.4 0.1 4.4 4 0 0 4 4 4 0 Zinc-finger associated domain (zf-AD) Zn-ribbon_8 PF09723.10 KFP08086.1 - 1.5 9.0 23.4 1.6 8.9 3.5 4.5 3 2 0 3 3 3 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 KFP08086.1 - 2.5 8.1 24.6 0.34 10.8 0.9 5.5 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 KFP08086.1 - 2.6 8.5 37.6 3.4 8.0 1.8 6.6 2 2 3 6 6 6 0 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 KFP08086.1 - 3.2 7.4 29.9 2.7 7.6 0.1 5.8 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger TMF_TATA_bd PF12325.8 KFP08088.1 - 0.011 15.9 14.9 0.011 15.9 14.9 6.9 3 2 3 7 7 7 0 TATA element modulatory factor 1 TATA binding zf-HC5HC2H_2 PF13832.6 KFP08089.1 - 1.1e-32 112.4 2.8 1.1e-32 112.4 2.8 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFP08089.1 - 3.8e-28 97.6 2.1 3.8e-28 97.6 2.1 3.8 4 0 0 4 4 4 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KFP08089.1 - 7.7e-13 47.8 6.4 7.7e-13 47.8 6.4 3.6 4 0 0 4 4 4 1 PHD-finger PHD PF00628.29 KFP08089.1 - 9.2e-12 44.7 23.2 2.2e-10 40.3 8.7 3.2 3 0 0 3 3 3 2 PHD-finger EPL1 PF10513.9 KFP08089.1 - 8.8e-06 26.2 0.1 8.8e-06 26.2 0.1 3.4 4 1 0 4 4 3 1 Enhancer of polycomb-like C1_1 PF00130.22 KFP08089.1 - 0.0036 17.2 4.3 0.0036 17.2 4.3 3.4 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FidL_like PF15941.5 KFP08089.1 - 0.0055 17.1 0.2 0.013 15.9 0.2 1.6 1 0 0 1 1 1 1 FidL-like putative membrane protein C1_2 PF03107.16 KFP08089.1 - 0.0056 17.0 18.7 0.13 12.6 4.8 3.6 3 0 0 3 3 3 2 C1 domain zf-RING-like PF08746.11 KFP08089.1 - 0.02 15.2 4.6 0.02 15.2 4.6 3.2 3 0 0 3 3 3 0 RING-like domain Prok-RING_1 PF14446.6 KFP08089.1 - 4.3 7.4 19.4 0.81 9.7 7.4 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 KFP08089.1 - 7 7.1 21.1 0.28 11.5 2.1 3.0 2 1 0 2 2 2 0 Ring finger domain La PF05383.17 KFP08090.1 - 8.9e-22 76.9 0.1 2.4e-21 75.5 0.1 1.8 1 0 0 1 1 1 1 La domain Vault PF01505.18 KFP08090.1 - 0.0045 17.1 0.0 0.014 15.5 0.0 1.9 1 0 0 1 1 1 1 Major Vault Protein repeat domain BMFP PF04380.13 KFP08090.1 - 0.085 13.4 0.0 0.24 11.9 0.0 1.7 1 0 0 1 1 1 0 Membrane fusogenic activity SGP PF17228.2 KFP08090.1 - 0.61 11.0 4.7 1.8 9.5 4.7 1.8 1 0 0 1 1 1 0 Sulphur globule protein DUF5320 PF17253.2 KFP08090.1 - 2.6 9.2 8.3 0.34 12.0 2.8 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DUF2048 PF09752.9 KFP08091.1 - 2.6e-151 503.7 0.0 3e-151 503.5 0.0 1.0 1 0 0 1 1 1 1 Abhydrolase domain containing 18 Peptidase_S15 PF02129.18 KFP08091.1 - 0.018 14.7 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 KFP08091.1 - 0.03 14.0 0.5 0.19 11.3 0.0 2.3 3 0 0 3 3 3 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFP08091.1 - 0.12 11.6 0.1 1.8 7.8 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 MFS_1 PF07690.16 KFP08092.1 - 6.1e-36 124.1 30.9 8.7e-29 100.5 20.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP08092.1 - 6.3e-09 35.2 9.7 6.3e-09 35.2 9.7 3.6 3 1 1 4 4 4 2 Sugar (and other) transporter SLATT_5 PF18160.1 KFP08092.1 - 0.18 11.1 0.7 0.42 9.9 0.7 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Pam17 PF08566.10 KFP08092.1 - 0.68 9.8 3.9 6.3 6.6 0.1 2.9 3 0 0 3 3 3 0 Mitochondrial import protein Pam17 TMEM174 PF15029.6 KFP08092.1 - 3.2 7.4 4.9 1.4 8.6 0.6 2.3 2 0 0 2 2 2 0 Transmembrane protein 174 HSP70 PF00012.20 KFP08093.1 - 1.2e-173 578.5 11.5 6.7e-165 549.7 0.3 2.8 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 KFP08093.1 - 5.6e-08 32.0 0.0 9.6e-08 31.2 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein SEEEED PF14797.6 KFP08093.1 - 5.5 7.2 14.8 13 6.0 14.8 1.5 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex Ank_2 PF12796.7 KFP08094.1 - 3.6e-104 341.5 23.2 3.2e-14 53.3 0.0 9.8 2 2 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP08094.1 - 9.1e-99 322.7 22.0 3.5e-11 43.4 0.0 14.7 2 2 13 16 16 16 14 Ankyrin repeats (many copies) Ank PF00023.30 KFP08094.1 - 3e-78 255.1 43.4 6.5e-06 26.4 0.1 19.3 19 0 0 19 19 19 16 Ankyrin repeat Ank_5 PF13857.6 KFP08094.1 - 1.7e-73 241.7 37.4 1.3e-09 38.1 0.1 12.3 4 3 10 14 14 14 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP08094.1 - 2.5e-66 211.7 16.8 0.00021 21.5 0.0 18.7 19 0 0 19 19 19 13 Ankyrin repeat AAA_16 PF13191.6 KFP08094.1 - 0.0014 19.1 0.1 0.037 14.4 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 KFP08094.1 - 0.014 15.4 0.2 0.064 13.2 0.2 2.1 1 1 0 1 1 1 0 NACHT domain Sprouty PF05210.13 KFP08095.1 - 6.4e-27 94.0 32.3 7.1e-27 93.8 31.2 1.6 1 1 0 1 1 1 1 Sprouty protein (Spry) AAA PF00004.29 KFP08096.1 - 5e-91 302.0 0.0 5.7e-45 153.0 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFP08096.1 - 2.1e-15 56.8 0.0 7.5e-08 32.3 0.0 3.2 2 2 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 KFP08096.1 - 4.8e-14 51.9 0.2 1e-09 38.1 0.2 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA_5 PF07728.14 KFP08096.1 - 2.7e-12 46.9 0.1 0.00018 21.5 0.0 3.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KFP08096.1 - 2.3e-10 40.2 0.1 0.00017 21.0 0.0 3.1 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_16 PF13191.6 KFP08096.1 - 6.6e-10 39.6 0.7 0.00041 20.8 0.0 4.0 2 2 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 KFP08096.1 - 1.4e-09 38.3 0.0 0.00036 20.7 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFP08096.1 - 1.2e-07 32.0 0.6 0.014 15.6 0.1 4.3 2 2 1 3 3 3 1 AAA domain Mg_chelatase PF01078.21 KFP08096.1 - 3.1e-07 30.0 0.7 0.0077 15.6 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KFP08096.1 - 4e-07 30.3 0.0 0.0044 17.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KFP08096.1 - 4.5e-07 29.8 0.0 0.0089 15.8 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 KFP08096.1 - 1.6e-06 28.5 0.0 0.0074 16.7 0.0 2.4 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.6 KFP08096.1 - 3.1e-06 26.9 0.2 0.54 9.8 0.0 4.0 3 1 1 4 4 4 2 AAA domain Parvo_NS1 PF01057.17 KFP08096.1 - 6.4e-06 25.4 0.1 0.0046 16.1 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_14 PF13173.6 KFP08096.1 - 7.4e-06 26.0 0.0 0.039 14.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.6 KFP08096.1 - 7.6e-06 26.1 0.0 0.045 13.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Rad17 PF03215.15 KFP08096.1 - 1.1e-05 25.4 0.0 0.023 14.6 0.0 2.8 2 1 1 3 3 3 1 Rad17 P-loop domain AAA_28 PF13521.6 KFP08096.1 - 1.2e-05 25.7 0.0 0.029 14.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KFP08096.1 - 1.3e-05 24.8 0.0 0.12 11.8 0.0 3.2 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_18 PF13238.6 KFP08096.1 - 1.4e-05 25.7 0.0 0.0075 16.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KFP08096.1 - 1.5e-05 24.9 0.0 0.34 10.8 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KFP08096.1 - 3.2e-05 23.9 0.0 0.13 12.3 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE CDC48_N PF02359.18 KFP08096.1 - 4.5e-05 23.5 0.0 9.9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain ATPase PF06745.13 KFP08096.1 - 0.00022 20.6 0.0 0.11 11.9 0.0 2.4 2 0 0 2 2 2 1 KaiC Sigma54_activat PF00158.26 KFP08096.1 - 0.00064 19.5 0.0 0.37 10.5 0.0 3.2 3 0 0 3 3 3 1 Sigma-54 interaction domain DUF815 PF05673.13 KFP08096.1 - 0.001 18.3 0.0 0.23 10.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KFP08096.1 - 0.0012 18.7 0.0 0.059 13.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KFP08096.1 - 0.0013 19.3 0.0 1.2 9.7 0.0 3.0 2 1 1 3 3 3 1 ABC transporter NACHT PF05729.12 KFP08096.1 - 0.0017 18.3 0.2 0.31 10.9 0.0 2.9 3 0 0 3 3 2 1 NACHT domain AAA_17 PF13207.6 KFP08096.1 - 0.002 18.5 0.0 1.2 9.5 0.0 3.0 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 KFP08096.1 - 0.005 16.1 0.2 1 8.6 0.1 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_11 PF13086.6 KFP08096.1 - 0.0051 16.6 0.0 0.92 9.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 KFP08096.1 - 0.014 14.8 0.0 2.4 7.5 0.0 3.5 4 0 0 4 4 4 0 Bacterial TniB protein AAA_19 PF13245.6 KFP08096.1 - 0.024 15.0 0.0 0.61 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain CDC48_2 PF02933.17 KFP08096.1 - 0.037 13.8 0.3 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 IPT PF01745.16 KFP08096.1 - 0.041 13.3 0.1 0.92 8.9 0.1 2.2 2 0 0 2 2 2 0 Isopentenyl transferase NB-ARC PF00931.22 KFP08096.1 - 0.043 13.0 0.0 1.5 8.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_6 PF12774.7 KFP08096.1 - 0.057 12.4 0.0 0.17 10.8 0.0 1.7 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region AAA_30 PF13604.6 KFP08096.1 - 0.062 13.0 0.1 0.62 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KFP08096.1 - 0.075 12.5 0.1 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein SKI PF01202.22 KFP08096.1 - 0.11 12.6 0.0 15 5.6 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase ATPase_2 PF01637.18 KFP08096.1 - 0.14 12.1 0.0 5.8 6.8 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Cytidylate_kin PF02224.18 KFP08096.1 - 0.15 11.8 0.1 4.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase Cytidylate_kin2 PF13189.6 KFP08096.1 - 0.21 11.7 0.0 4.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family MS_channel PF00924.18 KFP08096.1 - 0.22 11.0 0.1 0.38 10.3 0.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel NUDIX PF00293.28 KFP08097.1 - 3.5e-20 72.4 0.0 4.4e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Nudix_hydro PF18290.1 KFP08097.1 - 0.016 15.2 0.2 0.034 14.1 0.2 1.6 1 0 0 1 1 1 0 Nudix hydrolase domain FGF PF00167.18 KFP08098.1 - 1.3e-29 102.8 0.0 1.5e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor IL1 PF00340.19 KFP08098.1 - 0.00019 21.1 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 Interleukin-1 / 18 Glyco_transf_15 PF01793.16 KFP08098.1 - 0.068 12.4 0.1 0.069 12.4 0.1 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Cpn60_TCP1 PF00118.24 KFP08099.1 - 7e-19 67.8 0.3 7e-10 38.1 0.0 2.3 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family EF-hand_1 PF00036.32 KFP08100.1 - 2.2e-35 117.5 19.2 5.4e-09 35.0 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFP08100.1 - 7.6e-31 106.4 10.8 1.9e-16 60.2 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP08100.1 - 2.8e-27 92.3 12.2 3.3e-09 35.9 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KFP08100.1 - 2.4e-24 84.9 18.3 3e-11 43.0 1.1 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 KFP08100.1 - 1.6e-16 60.3 0.5 4.4e-07 30.1 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFP08100.1 - 2.9e-16 58.1 19.9 1.1e-05 24.7 0.3 4.6 4 1 0 4 4 4 4 EF hand EF-hand_4 PF12763.7 KFP08100.1 - 2.6e-06 27.3 9.3 0.29 11.1 0.1 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KFP08100.1 - 6.1e-05 23.1 1.8 0.2 11.9 0.2 2.7 1 1 2 3 3 3 2 Dockerin type I domain EF-hand_14 PF17959.1 KFP08100.1 - 0.00067 20.0 1.8 0.86 10.0 0.2 2.5 1 1 1 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KFP08100.1 - 0.0012 19.1 1.0 1.5 9.1 0.2 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF853 PF05872.12 KFP08100.1 - 0.0022 16.7 0.6 0.78 8.3 0.1 2.1 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF853) SurA_N_3 PF13624.6 KFP08100.1 - 0.0026 17.6 3.0 0.24 11.2 0.3 2.1 1 1 1 2 2 2 2 SurA N-terminal domain Sigma54_CBD PF04963.13 KFP08100.1 - 0.0029 17.5 0.2 0.0039 17.1 0.2 1.1 1 0 0 1 1 1 1 Sigma-54 factor, core binding domain SUB1_ProdP9 PF18213.1 KFP08100.1 - 0.0052 16.6 2.2 0.0061 16.4 0.3 1.9 1 1 1 2 2 2 1 SUB1 protease Prodomain ProdP9 SurA_N_2 PF13623.6 KFP08100.1 - 0.039 13.8 3.0 0.92 9.4 0.6 2.6 1 1 1 2 2 2 0 SurA N-terminal domain DUF3349 PF11829.8 KFP08100.1 - 0.044 14.6 2.9 8 7.3 0.1 3.0 1 1 3 4 4 4 0 Protein of unknown function (DUF3349) EF-hand_11 PF08976.11 KFP08100.1 - 0.053 14.4 0.2 7.4 7.5 0.1 2.1 1 1 1 2 2 2 0 EF-hand domain AAA_assoc_C PF09821.9 KFP08100.1 - 0.071 13.6 1.1 1.4 9.5 0.1 2.3 2 0 0 2 2 2 0 C-terminal AAA-associated domain PB1 PF00564.24 KFP08100.1 - 0.082 12.9 0.5 4.8 7.2 0.1 2.5 2 0 0 2 2 2 0 PB1 domain LETM1 PF07766.13 KFP08100.1 - 0.12 11.7 2.5 0.25 10.7 1.1 2.2 1 1 1 2 2 2 0 LETM1-like protein TerB PF05099.13 KFP08100.1 - 0.16 12.0 3.6 1.2 9.1 0.3 2.7 1 1 1 2 2 2 0 Tellurite resistance protein TerB PMBR PF09373.10 KFP08100.1 - 0.16 12.2 0.1 99 3.4 0.0 4.0 4 0 0 4 4 4 0 Pseudomurein-binding repeat Caleosin PF05042.13 KFP08100.1 - 0.21 11.5 2.7 10 6.0 0.0 3.2 1 1 3 4 4 4 0 Caleosin related protein DUF1542 PF07564.11 KFP08100.1 - 0.39 10.9 2.2 25 5.1 0.0 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) Gp-FAR-1 PF05823.12 KFP08100.1 - 0.64 10.4 7.1 0.66 10.3 0.2 3.0 2 1 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) SRI PF08236.11 KFP08100.1 - 2.4 8.4 6.2 2.2 8.5 0.4 3.0 2 1 1 3 3 3 0 SRI (Set2 Rpb1 interacting) domain Styelin PF17562.2 KFP08100.1 - 9.4 6.7 7.4 0.59 10.5 1.3 2.3 3 1 0 3 3 1 0 Styelin IL15 PF02372.15 KFP08101.1 - 6.3e-13 48.9 0.3 8.4e-13 48.5 0.3 1.1 1 0 0 1 1 1 1 Interleukin 15 IL15 PF02372.15 KFP08102.1 - 2e-34 118.5 6.5 1.2e-32 112.7 6.5 2.0 1 1 0 1 1 1 1 Interleukin 15 Ion_trans PF00520.31 KFP08103.1 - 1.1e-32 113.3 16.7 1.6e-32 112.7 16.4 1.4 1 1 0 1 1 1 1 Ion transport protein TRP_2 PF08344.11 KFP08103.1 - 6.9e-28 96.7 1.1 1.5e-27 95.6 1.1 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II PKD_channel PF08016.12 KFP08103.1 - 6.4e-13 48.2 15.8 2.5e-12 46.2 15.8 1.8 1 1 0 1 1 1 1 Polycystin cation channel Ank_2 PF12796.7 KFP08103.1 - 3.5e-11 43.5 0.1 5.2e-08 33.4 0.2 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP08103.1 - 1.7e-07 31.6 0.1 0.0024 18.4 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP08103.1 - 1e-06 28.9 0.6 1 9.8 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP08103.1 - 1.3e-06 28.2 3.5 1.8 9.4 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KFP08103.1 - 0.00027 21.2 0.4 2.5 8.7 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat BBS2_C PF14782.6 KFP08104.1 - 0.00023 20.1 0.5 0.00044 19.1 0.5 1.4 1 1 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal FlxA PF14282.6 KFP08104.1 - 0.00077 19.4 0.4 0.0017 18.3 0.4 1.5 1 0 0 1 1 1 1 FlxA-like protein BBS2_Mid PF14783.6 KFP08104.1 - 0.0026 17.8 0.0 0.011 15.8 0.0 2.1 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region HEPN_LA2681 PF18733.1 KFP08104.1 - 0.13 11.5 1.3 0.16 11.3 0.1 1.6 2 0 0 2 2 2 0 LA2681-like HEPN Cyclin_N PF00134.23 KFP08105.1 - 1.5e-49 166.9 0.2 2.8e-49 166.1 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP08105.1 - 2.3e-30 105.1 0.8 1.1e-29 103.0 0.2 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N2 PF16500.5 KFP08105.1 - 4.1e-05 24.4 0.7 7e-05 23.6 0.7 1.4 1 0 0 1 1 1 1 N-terminal region of cyclin_N RNase_PH PF01138.21 KFP08106.1 - 9.3e-17 61.8 0.0 1.7e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFP08106.1 - 1.1e-12 47.8 0.1 3e-12 46.4 0.1 1.8 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Annexin PF00191.20 KFP08107.1 - 9.1e-99 323.6 9.1 9.8e-25 86.4 0.2 4.0 4 0 0 4 4 4 4 Annexin DUF5069 PF16798.5 KFP08107.1 - 0.06 13.5 0.1 14 5.9 0.0 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF5069) CC2-LZ PF16516.5 KFP08108.1 - 5.5e-13 49.1 11.8 6.8e-13 48.8 10.5 1.8 1 1 0 1 1 1 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Spc7 PF08317.11 KFP08108.1 - 0.0014 17.6 12.0 0.0019 17.1 12.0 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein HemX PF04375.14 KFP08108.1 - 0.0023 17.3 2.4 0.0032 16.8 2.4 1.2 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase DUF2968 PF11180.8 KFP08108.1 - 0.0058 16.3 6.7 0.0096 15.6 6.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) HAUS-augmin3 PF14932.6 KFP08108.1 - 0.016 14.8 7.1 0.016 14.8 7.1 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 FlxA PF14282.6 KFP08108.1 - 0.017 15.1 2.5 0.044 13.8 2.5 1.6 1 0 0 1 1 1 0 FlxA-like protein DUF4061 PF13270.6 KFP08108.1 - 0.026 14.8 3.3 0.026 14.8 3.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) DUF2353 PF09789.9 KFP08108.1 - 1.1 8.6 13.5 1.9 7.8 13.5 1.4 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) JIP_LZII PF16471.5 KFP08108.1 - 1.1 9.5 12.6 1.9 8.7 5.5 2.8 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF4407 PF14362.6 KFP08108.1 - 2.2 7.6 5.6 5 6.4 5.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MRP-S26 PF14943.6 KFP08108.1 - 3.6 7.5 12.0 4.6 7.1 12.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF2369 PF10179.9 KFP08109.1 - 9e-36 122.2 2.5 8.7e-31 106.2 1.0 3.1 3 0 0 3 3 3 2 Uncharacterised conserved protein (DUF2369) fn3 PF00041.21 KFP08109.1 - 5.1e-09 36.3 0.3 0.0064 16.8 0.0 3.8 3 0 0 3 3 3 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFP08109.1 - 1.3e-05 25.6 0.2 0.12 12.9 0.0 2.8 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain zf-H2C2_2 PF13465.6 KFP08110.1 - 1.4e-71 233.9 117.4 2.4e-10 40.3 0.6 16.7 17 0 0 17 17 17 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFP08110.1 - 3.9e-70 228.6 110.7 1.7e-06 28.2 0.6 16.2 16 0 0 16 16 16 16 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP08110.1 - 9.8e-59 190.9 113.1 0.00019 22.0 0.2 16.2 16 0 0 16 16 16 16 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP08110.1 - 9.9e-34 114.9 98.5 7.9e-06 26.0 1.2 16.2 16 0 0 16 16 16 11 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP08110.1 - 8.1e-30 102.3 92.8 0.00013 22.2 1.8 15.7 16 0 0 16 16 16 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFP08110.1 - 2e-28 97.8 105.1 0.0011 18.9 0.6 16.7 15 2 1 16 16 16 10 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFP08110.1 - 2.3e-19 68.8 59.4 0.0037 17.0 0.1 14.0 15 0 0 15 15 15 7 zinc-finger C2H2-type zf-Di19 PF05605.12 KFP08110.1 - 2.6e-12 46.8 80.0 0.0031 17.8 1.9 9.4 5 3 3 9 9 9 7 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 KFP08110.1 - 4.1e-05 23.2 5.3 0.0027 17.4 0.3 15.0 15 3 0 15 15 14 3 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 KFP08110.1 - 0.0001 22.5 67.9 0.00074 19.8 2.5 8.5 1 1 8 9 9 9 2 C2H2-type zinc ribbon zf_UBZ PF18439.1 KFP08110.1 - 0.00037 20.0 67.9 0.21 11.2 0.2 14.7 16 0 0 16 16 16 3 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 KFP08110.1 - 0.0038 17.5 90.9 0.61 10.5 0.9 13.4 1 1 11 12 12 10 4 C2H2 type zinc-finger (2 copies) Trm112p PF03966.16 KFP08110.1 - 0.0085 16.6 15.3 0.15 12.7 1.1 5.5 3 3 1 4 4 3 1 Trm112p-like protein zf-C2H2_3rep PF18868.1 KFP08110.1 - 0.011 16.4 8.3 0.011 16.4 8.3 8.1 1 1 5 6 6 6 0 Zinc finger C2H2-type, 3 repeats zinc_ribbon_9 PF14369.6 KFP08110.1 - 0.069 13.4 42.8 3.6 7.9 0.1 11.2 12 0 0 12 12 11 0 zinc-ribbon BolA PF01722.18 KFP08110.1 - 0.091 13.0 21.6 5.8 7.3 0.1 7.1 4 3 3 7 7 7 0 BolA-like protein FerB PF08150.12 KFP08110.1 - 0.24 12.0 0.6 2.5 8.8 0.3 2.9 1 1 1 2 2 2 0 FerB (NUC096) domain TRAF6_Z2 PF18048.1 KFP08110.1 - 0.4 10.8 0.1 0.4 10.8 0.1 7.3 9 0 0 9 9 8 0 TNF receptor-associated factor 6 zinc finger 2 DUF3268 PF11672.8 KFP08110.1 - 0.61 10.4 38.9 0.12 12.7 3.7 7.2 5 2 3 8 8 8 0 zinc-finger-containing domain zf_C2H2_10 PF18414.1 KFP08110.1 - 1.5 8.4 12.3 2.6 7.6 0.0 5.4 5 0 0 5 5 5 0 C2H2 type zinc-finger zinc_ribbon_15 PF17032.5 KFP08110.1 - 2.9 8.7 75.5 1.2 9.9 2.1 8.7 2 1 7 9 9 9 0 zinc-ribbon family VGCC_beta4Aa_N PF12052.8 KFP08110.1 - 5.2 7.3 6.8 0.31 11.2 0.2 2.2 2 0 0 2 2 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal PLA2_B PF01735.18 KFP08111.1 - 4.1e-154 513.6 0.0 4.5e-153 510.2 0.0 2.0 1 1 0 1 1 1 1 Lysophospholipase catalytic domain C2 PF00168.30 KFP08111.1 - 1.6e-16 60.4 0.1 3.3e-16 59.4 0.1 1.5 1 0 0 1 1 1 1 C2 domain DUF2281 PF10047.9 KFP08111.1 - 0.061 14.0 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) An_peroxidase PF03098.15 KFP08112.1 - 8.8e-56 189.6 0.0 4e-49 167.6 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase EGF PF00008.27 KFP08112.1 - 3.6e-05 24.0 13.2 7.5e-05 22.9 13.2 1.6 1 0 0 1 1 1 1 EGF-like domain EGF_2 PF07974.13 KFP08112.1 - 0.082 13.3 15.2 0.17 12.3 15.2 1.5 1 0 0 1 1 1 0 EGF-like domain Phosducin PF02114.16 KFP08113.1 - 5.2e-113 376.4 1.1 6.1e-113 376.1 1.1 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 KFP08113.1 - 0.00074 19.5 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin ODR4-like PF14778.6 KFP08114.1 - 8.7e-117 390.2 0.2 1.1e-116 389.8 0.2 1.1 1 0 0 1 1 1 1 Olfactory receptor 4-like DUF4432 PF14486.6 KFP08114.1 - 0.12 11.1 0.1 0.33 9.7 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4432) TPR_MLP1_2 PF07926.12 KFP08115.1 - 1.5e-33 115.6 33.4 1.5e-33 115.6 33.4 16.1 7 4 8 15 15 15 8 TPR/MLP1/MLP2-like protein GRP PF07172.11 KFP08115.1 - 7.6 7.3 8.3 99 3.7 8.3 3.1 1 0 0 1 1 1 0 Glycine rich protein family Somatomedin_B PF01033.17 KFP08116.1 - 1.6e-20 73.2 43.8 1.1e-10 41.7 17.7 3.0 3 0 0 3 3 3 2 Somatomedin B domain Hemopexin PF00045.19 KFP08116.1 - 1.6e-15 56.8 5.2 1.6e-11 43.9 0.0 3.8 5 0 0 5 5 5 2 Hemopexin RGS PF00615.19 KFP08117.1 - 3e-40 137.2 7.3 3.4e-40 137.0 7.3 1.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain COMPASS-Shg1 PF05205.12 KFP08117.1 - 0.021 15.5 0.3 0.028 15.1 0.3 1.2 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 Peptidase_C12 PF01088.21 KFP08118.1 - 1.3e-60 204.7 0.0 2.6e-60 203.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KFP08118.1 - 2e-20 72.4 4.8 4.1e-20 71.4 4.8 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases RcsD_ABL PF16359.5 KFP08118.1 - 0.017 15.3 0.4 0.034 14.3 0.4 1.5 1 0 0 1 1 1 0 RcsD-ABL domain TROVE PF05731.11 KFP08119.1 - 9.9e-52 176.5 0.6 6.4e-48 163.9 1.0 2.3 1 1 1 2 2 2 2 TROVE domain DUF2201 PF09967.9 KFP08119.1 - 0.002 18.3 1.3 0.0029 17.7 0.3 1.8 2 0 0 2 2 2 1 VWA-like domain (DUF2201) DUF3046 PF11248.8 KFP08119.1 - 0.027 14.8 0.0 0.11 12.9 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3046) Glutaredoxin PF00462.24 KFP08120.1 - 1.6e-20 73.1 0.0 1.9e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 KFP08120.1 - 0.00031 20.7 0.0 0.00039 20.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.6 KFP08120.1 - 0.0053 17.2 0.0 0.0063 17.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 KFP08120.1 - 0.0083 16.1 0.0 0.0092 15.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DUF836 PF05768.14 KFP08120.1 - 0.015 15.7 0.0 0.02 15.3 0.0 1.3 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 KFP08120.1 - 0.017 14.9 0.2 1 9.1 0.0 2.0 1 1 0 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_7 PF13899.6 KFP08120.1 - 0.16 12.2 0.1 0.29 11.4 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like T2SSM_b PF10741.9 KFP08120.1 - 0.17 11.7 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b CDC73_N PF16050.5 KFP08121.1 - 5.3e-107 357.5 4.6 7.5e-107 357.0 4.6 1.2 1 0 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal CDC73_C PF05179.14 KFP08121.1 - 1.3e-50 171.1 0.0 2.7e-50 170.1 0.0 1.5 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal Galactosyl_T PF01762.21 KFP08122.1 - 8.3e-66 221.5 0.0 1.2e-65 221.0 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase BK_channel_a PF03493.18 KFP08123.1 - 1.2e-31 108.7 2.6 1.5e-31 108.4 0.5 2.4 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 KFP08123.1 - 1.5e-12 47.3 4.2 7.8e-12 45.0 4.1 2.2 2 0 0 2 2 2 1 Ion channel Castor_Poll_mid PF06241.12 KFP08123.1 - 0.051 13.5 0.0 2.7 8.0 0.0 2.8 2 0 0 2 2 2 0 Castor and Pollux, part of voltage-gated ion channel Sushi PF00084.20 KFP08124.1 - 1.2e-152 496.5 150.5 3.1e-11 43.7 0.5 19.6 20 0 0 20 20 20 18 Sushi repeat (SCR repeat) Sushi PF00084.20 KFP08125.1 - 4.2e-56 187.4 58.9 2.9e-09 37.4 1.2 9.4 9 0 0 9 9 9 8 Sushi repeat (SCR repeat) Sushi_2 PF09014.10 KFP08125.1 - 0.00022 21.0 17.4 0.054 13.4 0.3 6.4 5 2 2 7 7 7 2 Beta-2-glycoprotein-1 fifth domain DUF1962 PF09227.10 KFP08125.1 - 0.064 13.6 11.9 0.93 9.9 0.2 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF1962) zf-H2C2_2 PF13465.6 KFP08126.1 - 3.8e-47 156.7 129.1 1.8e-06 28.1 0.9 15.6 16 0 0 16 16 16 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFP08126.1 - 1.1e-42 142.1 143.3 0.00013 22.2 1.3 15.0 14 1 0 14 14 14 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP08126.1 - 5.2e-34 114.0 133.4 0.0051 17.5 2.8 14.8 14 0 0 14 14 14 13 C2H2-type zinc finger BTB PF00651.31 KFP08126.1 - 5.1e-21 75.0 0.5 1.3e-20 73.7 0.5 1.7 1 0 0 1 1 1 1 BTB/POZ domain zf-met PF12874.7 KFP08126.1 - 8.6e-08 32.3 89.5 0.00045 20.5 1.4 13.3 14 0 0 14 14 13 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFP08126.1 - 1.4e-07 31.4 122.9 0.019 14.9 2.9 13.7 14 0 0 14 14 14 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP08126.1 - 0.00089 19.5 91.6 0.027 14.8 2.5 13.2 14 0 0 14 14 14 6 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFP08126.1 - 0.054 13.3 16.1 4.9 7.0 0.1 6.4 3 2 3 6 6 6 0 GAGA factor zf-C2HC_2 PF13913.6 KFP08126.1 - 0.09 12.7 0.2 0.09 12.7 0.2 12.2 14 0 0 14 14 13 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 KFP08126.1 - 0.11 12.8 0.2 0.11 12.8 0.2 13.0 3 1 8 12 12 10 0 C2H2 type zinc-finger (2 copies) Thioredoxin_2 PF13098.6 KFP08126.1 - 0.16 12.4 1.7 1 9.9 1.7 2.4 1 0 0 1 1 1 0 Thioredoxin-like domain BolA PF01722.18 KFP08126.1 - 1.2 9.5 12.0 25 5.3 0.1 5.1 3 2 1 4 4 4 0 BolA-like protein EGF PF00008.27 KFP08127.1 - 7.4e-92 301.1 282.8 1.6e-07 31.5 6.4 20.0 19 1 0 19 19 19 17 EGF-like domain Laminin_G_2 PF02210.24 KFP08127.1 - 3.2e-50 169.9 1.2 1.9e-18 67.3 0.0 3.4 3 0 0 3 3 3 3 Laminin G domain hEGF PF12661.7 KFP08127.1 - 1.7e-46 155.4 226.6 0.00023 21.7 3.7 20.2 20 0 0 20 20 20 17 Human growth factor-like EGF Laminin_G_1 PF00054.23 KFP08127.1 - 1.9e-38 131.7 0.3 1.6e-14 54.2 0.0 3.6 3 0 0 3 3 3 3 Laminin G domain EGF_CA PF07645.15 KFP08127.1 - 7.5e-18 64.5 262.3 1.7e-05 25.0 5.7 19.8 14 4 6 20 20 20 12 Calcium-binding EGF domain EGF_2 PF07974.13 KFP08127.1 - 2e-11 44.0 294.9 0.041 14.3 8.0 18.6 19 0 0 19 19 19 15 EGF-like domain Laminin_G_3 PF13385.6 KFP08127.1 - 2e-06 28.0 0.0 0.011 15.9 0.0 3.2 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily cEGF PF12662.7 KFP08127.1 - 0.00064 19.6 14.9 0.00096 19.0 3.8 17.7 18 0 0 18 18 18 10 Complement Clr-like EGF-like DENN PF02141.21 KFP08128.1 - 6.5e-49 166.4 3.2 1.1e-48 165.6 3.2 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 KFP08128.1 - 2e-09 37.3 1.1 4.8e-09 36.1 1.1 1.7 1 0 0 1 1 1 1 dDENN domain Cwf_Cwc_15 PF04889.12 KFP08128.1 - 0.08 12.7 6.9 0.17 11.6 6.9 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CAP-ZIP_m PF15255.6 KFP08128.1 - 0.4 11.0 2.8 1.4 9.1 1.1 2.2 2 0 0 2 2 2 0 WASH complex subunit CAP-Z interacting, central region Pkinase PF00069.25 KFP08129.1 - 2e-65 220.8 0.0 2.5e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP08129.1 - 5.6e-48 163.5 0.0 6.8e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP08129.1 - 5.3e-06 26.0 0.0 8.4e-06 25.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFP08129.1 - 1.7e-05 23.9 0.0 3.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KFP08129.1 - 0.00026 19.9 0.0 0.00033 19.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PIP49_C PF12260.8 KFP08129.1 - 0.0039 16.9 0.3 0.22 11.1 0.1 2.2 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 Kdo PF06293.14 KFP08129.1 - 0.0052 16.2 0.1 0.0082 15.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF309 PF03745.14 KFP08129.1 - 0.12 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF309) Gln_deamidase_2 PF18626.1 KFP08129.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutaminase APH PF01636.23 KFP08129.1 - 0.16 11.9 0.0 0.58 10.0 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family V-ATPase_G PF03179.15 KFP08130.1 - 8.3e-34 116.3 13.3 9.2e-34 116.1 13.3 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Baculo_p24 PF05073.12 KFP08130.1 - 0.07 12.9 2.8 0.095 12.5 2.8 1.2 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Perilipin PF03036.16 KFP08130.1 - 0.32 10.0 6.8 0.34 9.9 6.8 1.1 1 0 0 1 1 1 0 Perilipin family DUF3552 PF12072.8 KFP08130.1 - 0.35 10.3 16.2 0.51 9.7 16.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) GA-like PF17573.2 KFP08130.1 - 0.54 10.2 8.8 0.15 12.0 2.1 2.5 1 1 1 2 2 2 0 GA-like domain GA PF01468.17 KFP08130.1 - 0.84 10.0 6.2 1.1 9.6 0.0 2.9 3 0 0 3 3 3 0 GA module DUF883 PF05957.13 KFP08130.1 - 1.1 9.9 7.9 2.3 8.9 5.6 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) RabGAP-TBC PF00566.18 KFP08130.1 - 1.4 8.5 4.9 2.5 7.7 4.9 1.5 1 1 0 1 1 1 0 Rab-GTPase-TBC domain V-ATPase_G_2 PF16999.5 KFP08130.1 - 3.1 8.3 13.6 12 6.4 10.0 2.0 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit Y_phosphatase PF00102.27 KFP08131.1 - 2.5e-156 518.1 4.9 6.2e-82 274.7 0.0 2.7 3 0 0 3 3 3 2 Protein-tyrosine phosphatase fn3 PF00041.21 KFP08131.1 - 1.6e-08 34.7 4.6 0.00032 21.0 0.1 4.9 4 1 0 4 4 4 2 Fibronectin type III domain Y_phosphatase3 PF13350.6 KFP08131.1 - 6.5e-07 29.6 0.0 0.041 13.8 0.0 2.5 2 0 0 2 2 2 2 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFP08131.1 - 9e-06 25.9 0.1 0.24 11.5 0.0 4.4 4 1 0 4 4 4 2 Inositol hexakisphosphate DSPc PF00782.20 KFP08131.1 - 0.0024 17.7 0.0 0.076 12.8 0.0 3.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 KFP08131.1 - 0.0049 16.5 0.0 4.4 6.9 0.0 2.7 2 0 0 2 2 2 2 Tyrosine phosphatase family Anti-adapt_IraP PF10796.9 KFP08131.1 - 0.12 13.0 0.0 0.35 11.5 0.0 1.8 1 0 0 1 1 1 0 Sigma-S stabilisation anti-adaptor protein zf-C4 PF00105.18 KFP08132.1 - 2.9e-32 110.9 12.0 4.8e-32 110.2 12.0 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFP08132.1 - 5.6e-31 107.7 5.8 9e-31 107.1 5.8 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DUF2431 PF10354.9 KFP08132.1 - 0.13 12.6 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) zf-H2C2_2 PF13465.6 KFP08133.1 - 2.1e-19 69.0 20.9 1.4e-06 28.4 0.2 4.6 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFP08133.1 - 5.6e-12 45.4 33.4 0.0024 18.2 0.8 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP08133.1 - 9.9e-07 29.1 42.5 0.01 16.6 4.1 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger FYVE PF01363.21 KFP08133.1 - 3.9e-06 26.9 0.3 0.14 12.3 0.0 3.1 1 1 1 2 2 2 1 FYVE zinc finger DUF4587 PF15248.6 KFP08133.1 - 0.57 11.0 7.3 0.18 12.6 2.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4587) DZR PF12773.7 KFP08133.1 - 1.4 9.0 8.0 6.5 6.9 2.0 2.6 2 0 0 2 2 2 0 Double zinc ribbon GAGA PF09237.11 KFP08133.1 - 1.7 8.5 9.7 0.18 11.7 1.9 2.9 1 1 1 3 3 3 0 GAGA factor XPA_N PF01286.18 KFP08133.1 - 2.3 8.3 9.0 9.7 6.3 0.0 4.2 4 0 0 4 4 4 0 XPA protein N-terminal zf-C2H2_jaz PF12171.8 KFP08133.1 - 3.8 7.9 16.8 2.8 8.3 0.3 4.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-MYST PF17772.1 KFP08133.1 - 6.3 6.5 12.9 0.6 9.8 1.8 3.1 2 1 1 3 3 3 0 MYST family zinc finger domain Kinesin PF00225.23 KFP08134.1 - 7.7e-109 363.6 0.3 7.7e-109 363.6 0.3 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFP08134.1 - 1.5e-26 93.1 4.8 4.3e-26 91.6 0.1 2.9 2 0 0 2 2 2 1 Microtubule binding Kinesin_assoc PF16183.5 KFP08134.1 - 1.9e-13 51.0 21.9 3.3e-11 43.7 1.0 4.1 2 1 1 3 3 3 2 Kinesin-associated FHA PF00498.26 KFP08134.1 - 1e-08 35.4 0.1 2.6e-08 34.1 0.1 1.8 1 0 0 1 1 1 1 FHA domain KIF1B PF12423.8 KFP08134.1 - 0.031 14.7 0.1 0.13 12.7 0.1 2.1 1 0 0 1 1 1 0 Kinesin protein 1B Gluconate_2-dh3 PF13618.6 KFP08134.1 - 0.19 12.0 4.0 0.72 10.1 4.0 2.0 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Caps_synth_GfcC PF06251.11 KFP08134.1 - 1.8 8.1 14.4 1.3 8.6 0.1 2.8 2 1 0 2 2 2 0 Capsule biosynthesis GfcC Filament PF00038.21 KFP08134.1 - 6 6.3 45.2 3.6 7.1 13.0 3.5 3 1 1 4 4 4 0 Intermediate filament protein FapA PF03961.13 KFP08134.1 - 7.8 5.0 29.8 1.1 7.8 19.0 2.4 2 0 0 2 2 2 0 Flagellar Assembly Protein A DEAD PF00270.29 KFP08135.1 - 7.6e-44 149.6 1.6 1.4e-43 148.7 0.8 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP08135.1 - 2.1e-21 76.4 0.0 1.6e-19 70.3 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain zf-HIT PF04438.16 KFP08135.1 - 5.2e-08 32.6 1.8 8.5e-08 31.9 1.8 1.4 1 0 0 1 1 1 1 HIT zinc finger ResIII PF04851.15 KFP08135.1 - 3.6e-05 23.8 0.0 9.3e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 KFP08135.1 - 0.026 13.8 0.2 0.75 9.0 0.0 2.4 2 0 0 2 2 2 0 SecA DEAD-like domain AAA PF00004.29 KFP08135.1 - 0.051 14.0 0.9 0.15 12.4 0.4 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) CMS1 PF14617.6 KFP08135.1 - 0.061 12.7 0.2 0.18 11.1 0.2 1.8 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Toprim_C_rpt PF13368.6 KFP08135.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat CAMSAP_CKK PF08683.11 KFP08137.1 - 5e-54 181.5 0.1 9.5e-54 180.6 0.1 1.5 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated CAMSAP_CH PF11971.8 KFP08137.1 - 2e-36 123.7 1.8 5.4e-36 122.3 1.8 1.8 1 0 0 1 1 1 1 CAMSAP CH domain CAMSAP_CC1 PF17095.5 KFP08137.1 - 1.1e-24 86.0 4.9 1.1e-24 86.0 4.9 2.1 2 0 0 2 2 2 1 Spectrin-binding region of Ca2+-Calmodulin CH PF00307.31 KFP08137.1 - 0.059 13.6 0.0 0.23 11.7 0.0 2.0 1 0 0 1 1 1 0 Calponin homology (CH) domain WD40 PF00400.32 KFP08138.1 - 8.9e-28 96.0 14.6 2.8e-05 24.8 0.0 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP08138.1 - 8.3e-13 48.5 0.0 0.0001 22.5 0.0 4.8 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 KFP08138.1 - 9.3e-09 34.8 0.0 2.3e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 LisH-like dimerisation domain Vir_act_alpha_C PF10400.9 KFP08138.1 - 0.37 11.5 5.6 0.88 10.3 5.6 1.6 1 0 0 1 1 1 0 Virulence activator alpha C-term Fzo_mitofusin PF04799.13 KFP08138.1 - 1.7 8.2 5.0 3 7.4 5.0 1.3 1 0 0 1 1 1 0 fzo-like conserved region DUF4798 PF16055.5 KFP08138.1 - 1.9 8.8 5.5 20 5.5 1.9 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4798) OmpH PF03938.14 KFP08138.1 - 6.1 7.2 14.4 12 6.3 14.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MCLC PF05934.11 KFP08139.1 - 2.9e-165 551.2 10.4 5.1e-165 550.3 10.4 1.4 1 1 0 1 1 1 1 Mid-1-related chloride channel (MCLC) TPR_12 PF13424.6 KFP08140.1 - 3.7e-38 129.7 29.3 4.3e-11 42.9 6.2 5.6 4 2 1 6 6 5 5 Tetratricopeptide repeat GoLoco PF02188.17 KFP08140.1 - 3.6e-37 125.3 30.1 4.2e-10 38.9 0.3 4.5 4 0 0 4 4 4 4 GoLoco motif TPR_1 PF00515.28 KFP08140.1 - 2.3e-36 122.1 31.3 7.3e-07 28.8 0.6 8.1 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_7 PF13176.6 KFP08140.1 - 2.5e-32 108.5 22.4 4.8e-06 26.2 0.2 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 KFP08140.1 - 1.5e-20 71.6 31.0 8.5e-05 22.4 1.2 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 KFP08140.1 - 9.2e-20 69.2 23.7 0.00027 20.9 0.3 7.9 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 KFP08140.1 - 7.2e-19 67.0 26.6 0.00013 21.7 1.1 8.3 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_4 PF07721.14 KFP08140.1 - 8.2e-09 35.3 0.1 0.58 10.9 0.1 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP08140.1 - 2.3e-06 27.2 7.4 0.0025 17.3 4.6 2.8 2 1 0 2 2 2 2 MalT-like TPR region TPR_16 PF13432.6 KFP08140.1 - 4.6e-06 27.2 14.1 0.0029 18.2 1.4 6.2 4 1 1 5 5 5 1 Tetratricopeptide repeat Rapsyn_N PF10579.9 KFP08140.1 - 4.9e-06 26.6 2.4 6.4 6.9 0.1 5.9 4 2 3 7 7 7 1 Rapsyn N-terminal myristoylation and linker region TPR_14 PF13428.6 KFP08140.1 - 5.2e-06 26.8 7.1 0.72 10.8 0.3 6.3 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFP08140.1 - 0.0005 19.7 22.8 0.27 11.0 0.2 7.5 6 2 1 7 7 7 2 TPR repeat TPR_6 PF13174.6 KFP08140.1 - 0.011 16.3 7.6 5.2 7.9 0.4 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFP08140.1 - 0.032 14.6 17.1 23 5.7 0.1 7.3 7 0 0 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP08140.1 - 0.049 13.8 13.2 8.6 6.7 3.9 4.9 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 KFP08140.1 - 0.25 11.0 1.6 2.5 7.8 0.1 2.9 2 2 0 2 2 2 0 26S proteasome subunit RPN7 TPR_19 PF14559.6 KFP08140.1 - 0.46 11.0 12.7 30 5.2 0.0 5.5 4 2 1 5 5 5 0 Tetratricopeptide repeat Sec1 PF00995.23 KFP08141.1 - 2.1e-125 420.2 3.2 2.3e-125 420.0 3.2 1.0 1 0 0 1 1 1 1 Sec1 family DUF2621 PF11084.8 KFP08141.1 - 0.014 15.4 0.3 0.039 13.9 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) PDZ_3 PF17815.1 KFP08141.1 - 0.05 13.5 0.1 0.15 11.9 0.1 1.9 1 0 0 1 1 1 0 PDZ domain PRP38 PF03371.15 KFP08142.1 - 1.8e-57 194.0 0.0 2.5e-57 193.5 0.0 1.2 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 KFP08142.1 - 0.00085 19.9 42.3 0.00085 19.9 42.3 3.3 1 1 2 3 3 3 2 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Methyltransf_12 PF08242.12 KFP08143.1 - 0.017 15.8 0.0 0.039 14.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KFP08143.1 - 0.018 14.9 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KFP08143.1 - 0.048 14.4 0.0 0.1 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain NT-C2 PF10358.9 KFP08144.1 - 1.8e-10 40.7 0.0 3.8e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Mito_carr PF00153.27 KFP08145.1 - 7.4e-74 243.8 4.8 7.2e-26 90.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KFP08145.1 - 2.3e-21 73.7 6.6 5.8e-06 25.5 0.6 4.8 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFP08145.1 - 2.6e-20 72.7 2.1 1.2e-09 38.5 0.3 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP08145.1 - 1.3e-19 68.4 6.7 0.0003 20.5 0.0 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFP08145.1 - 9e-16 56.6 14.7 2.5e-05 23.6 0.1 4.8 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 KFP08145.1 - 2.4e-12 46.5 4.5 3.7e-09 36.3 0.3 4.2 2 2 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFP08145.1 - 3.5e-07 30.5 0.1 0.015 15.6 0.0 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KFP08145.1 - 3.4e-06 26.8 0.6 0.0027 17.5 0.0 3.5 2 2 2 4 4 4 1 EF hand Dockerin_1 PF00404.18 KFP08145.1 - 0.00021 21.4 1.9 0.11 12.7 0.1 3.4 3 1 0 3 3 3 1 Dockerin type I domain EF-hand_4 PF12763.7 KFP08145.1 - 0.00022 21.1 2.6 0.0058 16.6 0.1 2.7 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFP08145.1 - 0.0013 19.0 0.0 1.7 9.1 0.0 3.1 2 1 0 2 2 2 1 EF-hand domain DUF2340 PF10209.9 KFP08145.1 - 0.009 16.5 0.0 0.036 14.5 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2340) Sigma_reg_C PF13791.6 KFP08145.1 - 0.035 14.3 0.2 0.082 13.1 0.2 1.6 1 0 0 1 1 1 0 Sigma factor regulator C-terminal B5 PF03484.15 KFP08145.1 - 0.042 14.2 0.0 0.15 12.4 0.0 2.0 1 0 0 1 1 1 0 tRNA synthetase B5 domain TerB PF05099.13 KFP08145.1 - 0.074 13.0 0.1 0.89 9.5 0.1 2.2 2 0 0 2 2 2 0 Tellurite resistance protein TerB Caleosin PF05042.13 KFP08145.1 - 0.2 11.6 0.7 44 4.0 0.0 3.5 2 1 2 4 4 4 0 Caleosin related protein RhoGEF PF00621.20 KFP08146.1 - 2.9e-39 135.2 7.9 2.9e-39 135.2 7.9 1.7 2 0 0 2 2 1 1 RhoGEF domain SH3_2 PF07653.17 KFP08146.1 - 3.4e-23 81.1 0.0 5.5e-14 51.6 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 KFP08146.1 - 1.4e-17 63.2 0.1 6.9e-11 41.8 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KFP08146.1 - 3.9e-17 61.6 0.1 4.2e-13 48.7 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH2 PF00017.24 KFP08146.1 - 2.2e-15 56.5 0.5 8.8e-15 54.6 0.5 2.1 1 0 0 1 1 1 1 SH2 domain C1_1 PF00130.22 KFP08146.1 - 2.1e-09 37.1 4.9 3.9e-09 36.3 4.9 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 KFP08146.1 - 9.2e-08 32.5 0.1 2.3e-07 31.3 0.1 1.7 1 0 0 1 1 1 1 PH domain CH PF00307.31 KFP08146.1 - 2.1e-05 24.7 0.3 0.00013 22.1 0.0 2.5 3 0 0 3 3 2 1 Calponin homology (CH) domain Filamin PF00630.19 KFP08146.1 - 0.00044 21.0 0.1 0.0023 18.7 0.1 2.2 1 1 0 1 1 1 1 Filamin/ABP280 repeat C1_2 PF03107.16 KFP08146.1 - 0.0061 16.8 3.6 0.015 15.6 3.6 1.7 1 0 0 1 1 1 1 C1 domain Prok-RING_1 PF14446.6 KFP08146.1 - 0.0087 16.0 2.0 0.022 14.7 2.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 DUF2326 PF10088.9 KFP08146.1 - 0.027 14.2 0.3 5.6 6.7 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2326) PH_10 PF15411.6 KFP08146.1 - 0.081 13.2 2.1 0.15 12.3 0.1 2.5 3 0 0 3 3 3 0 Pleckstrin homology domain CAMSAP_CH PF11971.8 KFP08146.1 - 0.11 12.3 1.5 0.22 11.4 0.1 2.3 2 0 0 2 2 2 0 CAMSAP CH domain Zn_ribbon_17 PF17120.5 KFP08146.1 - 0.19 11.4 2.9 0.52 10.0 2.9 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type LZ3wCH PF18517.1 KFP08146.1 - 0.55 10.4 2.8 0.48 10.5 0.2 2.3 2 0 0 2 2 1 0 Leucine zipper with capping helix domain PHD PF00628.29 KFP08146.1 - 1 9.3 3.6 3.2 7.7 3.6 1.9 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 KFP08146.1 - 5.9 7.1 7.1 0.34 11.0 0.7 2.2 3 0 0 3 3 1 0 KIAA1045 RING finger Laminin_N PF00055.17 KFP08147.1 - 8.8e-56 189.1 0.0 8.8e-56 189.1 0.0 2.9 3 1 1 4 4 4 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 KFP08147.1 - 1.3e-22 79.6 62.0 2.3e-08 34.1 11.7 4.8 3 1 1 4 4 4 3 Laminin EGF domain EGF_2 PF07974.13 KFP08147.1 - 0.0026 18.1 8.7 0.0026 18.1 8.7 7.6 7 2 0 7 7 7 1 EGF-like domain hEGF PF12661.7 KFP08147.1 - 0.0061 17.2 6.8 0.0061 17.2 6.8 7.1 7 1 1 8 8 8 1 Human growth factor-like EGF EGF PF00008.27 KFP08147.1 - 0.0066 16.7 7.8 0.0066 16.7 7.8 6.3 5 2 0 5 5 5 1 EGF-like domain SF3b10 PF07189.11 KFP08148.1 - 1.6e-40 137.1 0.0 1.8e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF2264 PF10022.9 KFP08148.1 - 0.022 13.9 0.2 0.024 13.7 0.2 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) Syntaxin PF00804.25 KFP08149.1 - 2.6e-64 216.6 16.2 3.7e-64 216.1 16.2 1.2 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KFP08149.1 - 1.3e-05 25.1 2.4 3e-05 23.9 0.0 2.7 4 0 0 4 4 4 1 SNARE domain Herpes_BLRF2 PF05812.12 KFP08149.1 - 0.016 15.4 2.9 0.088 12.9 0.9 2.3 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein Spectrin PF00435.21 KFP08149.1 - 0.034 14.6 6.1 0.11 13.0 1.2 2.7 2 0 0 2 2 2 0 Spectrin repeat FUSC PF04632.12 KFP08149.1 - 0.35 9.4 0.4 0.44 9.0 0.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DivIC PF04977.15 KFP08149.1 - 0.45 10.3 7.2 0.075 12.8 0.8 2.7 3 0 0 3 3 3 0 Septum formation initiator HisKA_3 PF07730.13 KFP08149.1 - 2.3 8.8 6.8 2 9.0 0.6 3.3 3 2 2 5 5 5 0 Histidine kinase Prefoldin PF02996.17 KFP08149.1 - 2.7 7.9 7.6 0.39 10.6 0.2 3.0 3 1 0 3 3 3 0 Prefoldin subunit Occludin_ELL PF07303.13 KFP08149.1 - 3.3 8.5 7.6 1.2 9.9 1.3 2.7 3 0 0 3 3 3 0 Occludin homology domain CENP-H PF05837.12 KFP08149.1 - 6.3 7.3 9.6 0.54 10.7 2.2 2.5 2 1 1 3 3 3 0 Centromere protein H (CENP-H) CH PF00307.31 KFP08150.1 - 9.4e-44 148.1 1.5 5.3e-21 74.8 0.1 4.3 3 0 0 3 3 3 2 Calponin homology (CH) domain Spectrin PF00435.21 KFP08150.1 - 6.8e-38 129.4 79.7 2.4e-13 50.4 14.1 7.5 7 0 0 7 7 7 7 Spectrin repeat CAMSAP_CH PF11971.8 KFP08150.1 - 2.6e-05 23.9 0.0 0.03 14.1 0.0 3.6 4 0 0 4 4 4 2 CAMSAP CH domain Caskin-Pro-rich PF16907.5 KFP08150.1 - 0.092 13.3 0.7 0.22 12.1 0.7 1.6 1 0 0 1 1 1 0 Proline rich region of Caskin proteins DUF3288 PF11691.8 KFP08150.1 - 2.3 8.3 15.2 2.1 8.4 0.1 5.5 6 0 0 6 6 6 0 Protein of unknown function (DUF3288) Spectrin PF00435.21 KFP08151.1 - 6.7e-17 61.9 18.9 1e-10 42.1 5.1 3.0 2 1 1 3 3 3 2 Spectrin repeat NPV_P10 PF05531.12 KFP08151.1 - 0.016 15.7 13.6 0.34 11.4 0.6 4.3 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein MnmE_helical PF12631.7 KFP08151.1 - 0.082 13.1 5.0 0.11 12.7 5.0 1.1 1 0 0 1 1 1 0 MnmE helical domain DUF948 PF06103.11 KFP08151.1 - 0.12 12.7 7.3 36 4.7 0.0 4.1 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DASH_Dam1 PF08653.10 KFP08151.1 - 0.33 10.8 3.3 11 5.9 0.1 4.1 4 0 0 4 4 4 0 DASH complex subunit Dam1 Uteroglobin PF01099.17 KFP08151.1 - 0.61 10.5 3.9 2.7 8.4 1.6 2.6 2 0 0 2 2 2 0 Uteroglobin family Rab5-bind PF09311.11 KFP08151.1 - 1.2 8.5 19.5 1.6 8.1 5.0 2.9 2 1 1 3 3 3 0 Rabaptin-like protein FAD_SOX PF18371.1 KFP08151.1 - 1.4 9.4 6.4 27 5.2 0.0 3.6 1 1 2 4 4 4 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase DUF3461 PF11944.8 KFP08151.1 - 2.1 8.5 8.6 2.1 8.5 1.4 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF3461) HetR_C PF18460.1 KFP08151.1 - 2.5 8.1 8.3 0.62 10.0 0.2 3.4 2 1 1 4 4 4 0 Heterocyst differentiation regulator C-terminal Hood domain CorA PF01544.18 KFP08151.1 - 3 7.1 13.3 0.52 9.6 6.5 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein KxDL PF10241.9 KFP08151.1 - 4.8 7.5 9.1 8.9 6.7 1.3 3.5 3 1 0 3 3 3 0 Uncharacterized conserved protein TMPIT PF07851.13 KFP08151.1 - 5.6 6.1 8.0 10 5.2 1.3 2.4 2 1 0 2 2 2 0 TMPIT-like protein Exonuc_VII_L PF02601.15 KFP08151.1 - 7.3 6.1 10.8 1.5e+02 1.7 10.7 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit Sec5 PF15469.6 KFP08151.1 - 9.4 6.0 12.3 1 9.1 2.2 2.6 2 1 1 3 3 3 0 Exocyst complex component Sec5 DSPc PF00782.20 KFP08152.1 - 1.5e-13 50.7 0.0 2.8e-13 49.8 0.0 1.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 KFP08152.1 - 0.001 18.7 0.0 0.0026 17.4 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family AlaDh_PNT_N PF05222.15 KFP08152.1 - 0.033 14.5 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain AAA_25 PF13481.6 KFP08152.1 - 0.05 13.2 0.0 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain CDKN3 PF05706.12 KFP08152.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.4 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) F-box_4 PF15966.5 KFP08153.1 - 3e-50 168.9 0.7 3e-50 168.9 0.7 2.1 2 0 0 2 2 2 1 F-box zf-TRAF_2 PF15965.5 KFP08153.1 - 2.1e-38 130.7 15.0 2.1e-38 130.7 15.0 2.9 3 1 0 3 3 3 1 TRAF-like zinc-finger F-box PF00646.33 KFP08153.1 - 2.1e-07 30.6 0.8 5.9e-07 29.2 0.8 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFP08153.1 - 2.1e-06 27.5 0.2 6.2e-06 26.0 0.2 1.8 1 0 0 1 1 1 1 F-box-like zf-TRAF PF02176.18 KFP08153.1 - 0.0043 17.7 1.9 0.0043 17.7 1.9 4.3 5 0 0 5 5 5 1 TRAF-type zinc finger DUF4644 PF15486.6 KFP08153.1 - 0.022 14.5 0.2 5 6.9 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4644) Pentapeptide_4 PF13599.6 KFP08154.1 - 0.27 11.4 0.0 0.28 11.4 0.0 1.2 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) ANF_receptor PF01094.28 KFP08155.1 - 1.3e-87 294.2 0.0 2e-87 293.6 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 KFP08155.1 - 9.2e-57 192.5 27.4 1.4e-56 191.9 27.4 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR GluR_Homer-bdg PF10606.9 KFP08155.1 - 1.5e-24 85.9 8.3 4.5e-24 84.4 8.3 2.0 1 0 0 1 1 1 1 Homer-binding domain of metabotropic glutamate receptor NCD3G PF07562.14 KFP08155.1 - 2.1e-15 56.4 10.4 4.7e-15 55.3 10.4 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR DUF5438 PF17506.2 KFP08155.1 - 0.058 13.7 0.4 0.21 11.9 0.4 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5438) Ras PF00071.22 KFP08156.1 - 9.3e-39 132.6 0.0 1e-38 132.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP08156.1 - 6.2e-28 97.4 0.0 7.7e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP08156.1 - 2.9e-09 36.6 0.0 3.4e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFP08156.1 - 2.8e-06 26.9 0.0 3.1e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP08156.1 - 0.00025 21.1 0.0 0.00031 20.8 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 KFP08156.1 - 0.0019 17.7 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KFP08156.1 - 0.0022 18.3 0.0 0.003 17.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 KFP08156.1 - 0.0032 17.1 0.0 0.11 12.0 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KFP08156.1 - 0.0058 16.5 0.0 2 8.1 0.0 2.0 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KFP08156.1 - 0.042 14.2 0.1 0.063 13.7 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 KFP08156.1 - 0.051 13.3 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 KFP08156.1 - 0.056 12.8 0.0 0.27 10.6 0.0 1.8 1 1 1 2 2 2 0 Bacterial TniB protein TsaE PF02367.17 KFP08156.1 - 0.078 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KFP08156.1 - 0.091 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KFP08156.1 - 0.097 12.4 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KFP08156.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 KFP08156.1 - 0.14 12.6 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFP08156.1 - 0.17 11.9 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) cobW PF02492.19 KFP08156.1 - 0.21 11.2 0.0 1.1 8.8 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Globin PF00042.22 KFP08158.1 - 9.4e-08 32.6 0.1 1.8e-05 25.3 0.0 2.4 2 0 0 2 2 2 2 Globin IQ PF00612.27 KFP08158.1 - 0.014 15.1 0.1 0.038 13.8 0.1 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif TAFA PF12020.8 KFP08158.1 - 0.15 12.6 3.1 4.7 7.7 0.2 3.0 3 0 0 3 3 3 0 TAFA family DNA_alkylation PF08713.11 KFP08158.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 DNA alkylation repair enzyme Yae1_N PF09811.9 KFP08159.1 - 1.8e-11 43.6 33.2 1.5e+02 2.2 33.2 3.5 1 1 0 1 1 1 1 Essential protein Yae1, N terminal LLGL PF08366.13 KFP08160.1 - 5.7e-34 116.6 0.0 1.5e-33 115.3 0.0 1.8 1 0 0 1 1 1 1 LLGL2 ANAPC4_WD40 PF12894.7 KFP08160.1 - 2e-11 44.1 1.3 0.027 14.8 0.1 6.2 4 1 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFP08160.1 - 1.2e-08 35.4 11.7 0.0033 18.2 0.7 6.6 7 1 0 7 7 7 2 WD domain, G-beta repeat Lgl_C PF08596.10 KFP08160.1 - 1.6e-07 30.4 0.0 6.7e-06 25.1 0.0 3.1 4 0 0 4 4 4 1 Lethal giant larvae(Lgl) like, C-terminal WD40_like PF17005.5 KFP08160.1 - 0.0019 17.6 0.0 0.017 14.4 0.0 2.4 1 1 0 1 1 1 1 WD40-like domain Synaptobrevin PF00957.21 KFP08160.1 - 0.0028 17.4 0.0 0.007 16.1 0.0 1.6 1 0 0 1 1 1 1 Synaptobrevin ELYS-bb PF16687.5 KFP08160.1 - 0.0051 15.5 0.0 9 4.8 0.0 3.3 2 1 1 3 3 3 1 beta-propeller of ELYS nucleoporin Frtz PF11768.8 KFP08160.1 - 0.006 15.0 0.1 0.016 13.5 0.0 1.7 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz RAB3GAP2_N PF14655.6 KFP08160.1 - 0.01 15.2 0.0 7.4 5.7 0.0 3.4 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Hira PF07569.11 KFP08160.1 - 0.048 13.4 0.0 2.2 8.0 0.0 3.2 2 1 2 4 4 4 0 TUP1-like enhancer of split SAM_1 PF00536.30 KFP08161.1 - 5.5e-14 52.4 0.0 7.3e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP08161.1 - 1.3e-10 41.3 0.0 2.5e-10 40.3 0.0 1.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) NCD1 PF04904.13 KFP08161.1 - 0.045 13.8 0.0 0.064 13.3 0.0 1.2 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) CAP_N PF01213.19 KFP08161.1 - 0.55 9.7 3.4 0.66 9.4 3.4 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 KFP08161.1 - 5 7.2 7.0 7.2 6.7 7.0 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DEP PF00610.21 KFP08162.1 - 7.9e-40 134.8 0.1 3.7e-22 78.2 0.0 3.1 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGEF PF00621.20 KFP08162.1 - 1.6e-37 129.5 1.6 1.6e-37 129.5 1.6 2.3 2 0 0 2 2 2 1 RhoGEF domain PDZ PF00595.24 KFP08162.1 - 1.5e-10 41.2 0.1 7.7e-05 23.0 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFP08162.1 - 3e-10 39.8 0.0 1.6e-05 24.7 0.1 2.6 2 0 0 2 2 2 2 PDZ domain PH PF00169.29 KFP08162.1 - 1.5e-06 28.7 0.2 6.5e-06 26.6 0.2 2.2 1 0 0 1 1 1 1 PH domain PDZ_2 PF13180.6 KFP08162.1 - 0.00016 21.9 0.0 0.47 10.8 0.0 2.7 2 0 0 2 2 2 2 PDZ domain NPV_P10 PF05531.12 KFP08162.1 - 1 9.9 2.6 13 6.3 0.1 3.8 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF5586 PF17824.1 KFP08163.1 - 4.7e-196 651.7 13.2 5.3e-196 651.5 13.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5586) DEAD_assoc PF08494.11 KFP08163.1 - 0.089 12.6 0.2 0.16 11.8 0.2 1.3 1 0 0 1 1 1 0 DEAD/H associated Calpain_inhib PF00748.19 KFP08163.1 - 1.3 9.5 8.9 0.86 10.1 3.2 2.5 2 0 0 2 2 2 0 Calpain inhibitor DUF3740 PF12548.8 KFP08165.1 - 2.1e-60 203.4 15.4 3.2e-53 180.1 3.8 2.6 2 0 0 2 2 2 2 Sulfatase protein Sulfatase PF00884.23 KFP08165.1 - 2.4e-53 181.5 1.3 2.9e-53 181.3 0.5 1.6 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KFP08165.1 - 8.2e-05 22.4 3.2 0.0018 17.9 1.5 2.9 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Pentapeptide_4 PF13599.6 KFP08166.1 - 0.039 14.1 0.0 0.11 12.7 0.0 1.7 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) zf-C2H2 PF00096.26 KFP08168.1 - 1.2e-05 25.4 9.9 0.01 16.3 1.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP08168.1 - 1.6e-05 25.3 8.8 0.006 17.3 1.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger SET PF00856.28 KFP08168.1 - 0.00013 22.4 0.0 0.0037 17.7 0.0 2.2 1 1 0 1 1 1 1 SET domain zf-C2HC_2 PF13913.6 KFP08168.1 - 0.0064 16.4 1.9 0.0064 16.4 1.9 2.7 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KFP08168.1 - 0.011 15.3 2.1 0.48 10.1 0.2 2.8 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 KFP08168.1 - 0.026 14.9 1.5 5.7 7.5 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFP08168.1 - 0.033 14.2 6.8 0.33 11.0 0.3 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFP08168.1 - 0.22 11.7 4.4 8.6 6.6 1.5 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Zf_RING PF16744.5 KFP08168.1 - 0.72 10.0 3.7 6.6 6.9 0.4 2.4 1 1 1 2 2 2 0 KIAA1045 RING finger C1_2 PF03107.16 KFP08168.1 - 0.85 10.0 5.7 3.8 7.9 0.5 2.6 1 1 1 2 2 2 0 C1 domain zf-AN1 PF01428.16 KFP08168.1 - 1.4 9.1 6.1 5.6 7.2 0.1 3.0 3 0 0 3 3 3 0 AN1-like Zinc finger zf-BED PF02892.15 KFP08168.1 - 4.6 7.4 6.3 17 5.5 1.6 2.4 1 1 1 2 2 2 0 BED zinc finger NCOA_u2 PF16665.5 KFP08169.1 - 6.7e-38 129.6 16.6 6.7e-38 129.6 16.6 4.6 4 0 0 4 4 4 1 Unstructured region on nuclear receptor coactivator protein PAS_11 PF14598.6 KFP08169.1 - 1.3e-34 118.7 0.6 3.6e-31 107.6 0.7 2.5 2 0 0 2 2 2 2 PAS domain DUF4927 PF16279.5 KFP08169.1 - 8.9e-31 106.8 4.7 8.9e-31 106.8 4.7 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4927) DUF1518 PF07469.12 KFP08169.1 - 1.4e-24 86.2 15.5 1.4e-24 86.2 15.5 4.6 4 1 0 4 4 4 1 Domain of unknown function (DUF1518) Nuc_rec_co-act PF08815.10 KFP08169.1 - 8.9e-24 83.1 0.2 2.2e-23 81.8 0.2 1.7 1 0 0 1 1 1 1 Nuclear receptor coactivator SRC-1 PF08832.10 KFP08169.1 - 7.3e-21 75.0 4.2 7.3e-21 75.0 4.2 3.9 4 0 0 4 4 4 1 Steroid receptor coactivator PAS PF00989.25 KFP08169.1 - 1.1e-07 31.8 0.0 7.7e-07 29.1 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 KFP08169.1 - 1.3e-06 28.6 0.0 0.065 13.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KFP08169.1 - 8.3e-06 26.0 0.0 2.7e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 PAS domain HLH PF00010.26 KFP08169.1 - 0.0063 16.4 0.6 0.014 15.4 0.6 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TRAM_LAG1_CLN8 PF03798.16 KFP08170.1 - 3.6e-26 92.1 18.8 3.6e-26 92.1 18.8 1.4 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KFP08170.1 - 2.2e-22 78.5 2.7 2.6e-22 78.2 0.8 2.2 2 0 0 2 2 2 1 TRAM1-like protein DUF3671 PF12420.8 KFP08170.1 - 1.9 8.6 12.1 0.16 12.1 4.5 2.8 2 1 1 3 3 3 0 Protein of unknown function DUF4834 PF16118.5 KFP08170.1 - 5.9 7.9 9.3 5.3 8.1 0.3 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Lactamase_B PF00753.27 KFP08171.1 - 1.5e-20 74.1 1.0 2.1e-20 73.6 1.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 KFP08171.1 - 2.3e-18 65.9 0.1 5.2e-18 64.8 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 KFP08171.1 - 0.00041 19.9 0.2 0.00072 19.1 0.2 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain HTH_24 PF13412.6 KFP08171.1 - 0.068 12.7 0.0 7.4 6.2 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Metallophos_3 PF14582.6 KFP08171.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Trans_reg_C PF00486.28 KFP08171.1 - 0.15 12.1 0.1 0.58 10.3 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal XK-related PF09815.9 KFP08172.1 - 9.7e-90 301.1 31.4 1.1e-89 300.8 31.4 1.0 1 0 0 1 1 1 1 XK-related protein HigB_toxin PF09907.9 KFP08172.1 - 0.084 13.1 0.5 0.22 11.7 0.5 1.7 1 0 0 1 1 1 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system DUF4736 PF15883.5 KFP08172.1 - 0.55 9.9 4.2 0.17 11.6 0.3 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4736) CHGN PF05679.16 KFP08174.1 - 2.7e-193 643.5 0.8 3.1e-193 643.3 0.8 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 KFP08174.1 - 9.2e-10 38.1 0.3 2.1e-09 36.9 0.3 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Fringe PF02434.16 KFP08174.1 - 1.1e-06 28.3 0.1 1.9e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Fringe-like Glyco_tranf_2_2 PF10111.9 KFP08174.1 - 5e-05 22.9 0.1 0.0005 19.6 0.1 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 UPF0258 PF06789.12 KFP08175.1 - 4.4e-44 150.3 1.7 4.8e-44 150.2 1.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0258) COX7B PF05392.11 KFP08175.1 - 0.023 14.4 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase chain VIIB DUF1461 PF07314.11 KFP08175.1 - 0.043 13.7 0.0 0.043 13.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) DUF3899 PF13038.6 KFP08175.1 - 0.1 13.1 3.0 0.56 10.8 3.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3899) ADAM_spacer1 PF05986.14 KFP08176.1 - 4.6e-29 100.8 0.0 1e-28 99.7 0.0 1.6 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.19 KFP08176.1 - 4.7e-22 77.9 93.3 5.4e-08 32.9 11.9 7.1 7 1 0 7 7 6 5 Thrombospondin type 1 domain ADAM_CR_2 PF17771.1 KFP08176.1 - 2.5e-21 76.0 18.0 8.4e-21 74.3 8.5 6.0 6 1 0 6 6 3 2 ADAM cysteine-rich domain Pep_M12B_propep PF01562.19 KFP08176.1 - 2.9e-21 76.2 0.0 9.4e-21 74.5 0.0 1.8 2 0 0 2 2 2 1 Reprolysin family propeptide Reprolysin PF01421.19 KFP08176.1 - 5.5e-19 68.9 2.5 5.5e-19 68.9 2.5 3.3 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 KFP08176.1 - 1.2e-13 51.7 0.7 3e-13 50.4 0.7 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFP08176.1 - 3.8e-10 40.4 0.1 7.9e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFP08176.1 - 1.4e-06 28.3 0.7 3.7e-06 27.0 0.7 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP08176.1 - 1.8e-06 27.7 1.0 2.2e-05 24.2 1.0 2.2 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFP08176.1 - 0.00038 20.3 0.4 0.00067 19.5 0.4 1.3 1 0 0 1 1 1 1 Matrixin PLAC PF08686.11 KFP08176.1 - 0.0032 18.2 7.0 0.0032 18.2 7.0 3.0 2 0 0 2 2 1 1 PLAC (protease and lacunin) domain Peptidase_M66 PF10462.9 KFP08176.1 - 0.13 11.2 0.3 0.25 10.3 0.3 1.3 1 0 0 1 1 1 0 Peptidase M66 DUF3810 PF12725.7 KFP08176.1 - 0.2 11.0 0.1 0.32 10.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Ets PF00178.22 KFP08177.1 - 5.6e-23 81.2 0.2 6.5e-23 81.0 0.2 1.1 1 0 0 1 1 1 1 Ets-domain HSF_DNA-bind PF00447.17 KFP08177.1 - 0.035 14.7 0.0 0.041 14.5 0.0 1.2 1 0 0 1 1 1 0 HSF-type DNA-binding Clathrin PF00637.20 KFP08178.1 - 3.4e-27 95.1 1.1 3.4e-27 95.1 1.1 2.6 3 0 0 3 3 3 1 Region in Clathrin and VPS Vps39_2 PF10367.9 KFP08178.1 - 0.00064 20.1 0.2 0.002 18.6 0.2 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KFP08178.1 - 0.00072 19.8 5.4 0.0027 18.0 0.1 3.4 3 1 1 4 4 4 1 Vacuolar sorting protein 39 domain 1 ANAPC4_WD40 PF12894.7 KFP08178.1 - 0.0015 18.8 0.2 0.34 11.2 0.0 3.2 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_5 PF14634.6 KFP08178.1 - 0.0072 16.3 5.1 0.024 14.6 5.1 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3H2C3 PF17122.5 KFP08178.1 - 0.2 11.7 4.8 0.24 11.5 3.0 2.1 1 1 0 1 1 1 0 Zinc-finger zf-RING_2 PF13639.6 KFP08178.1 - 0.24 11.7 11.7 0.038 14.3 6.7 2.4 2 0 0 2 2 2 0 Ring finger domain zf-rbx1 PF12678.7 KFP08178.1 - 0.26 11.6 4.2 1 9.7 4.2 2.1 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KFP08178.1 - 0.69 9.7 8.2 0.24 11.2 4.5 2.2 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_UBOX PF13445.6 KFP08178.1 - 6.4 6.9 7.1 42 4.3 7.1 2.3 1 1 0 1 1 1 0 RING-type zinc-finger BAR PF03114.18 KFP08179.1 - 8.6e-51 172.9 7.2 8.6e-51 172.9 7.2 1.5 2 0 0 2 2 2 1 BAR domain SH3_9 PF14604.6 KFP08179.1 - 1.6e-09 37.4 0.0 3.9e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP08179.1 - 4.4e-06 26.2 0.1 4.8e-05 22.9 0.1 2.3 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP08179.1 - 0.00039 20.0 0.0 0.00083 19.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 KFP08179.1 - 0.00081 19.2 2.5 0.0017 18.1 2.5 1.5 1 1 0 1 1 1 1 BAR domain of APPL family Arfaptin PF06456.13 KFP08179.1 - 0.0076 15.8 3.6 0.012 15.2 3.6 1.3 1 0 0 1 1 1 1 Arfaptin-like domain EzrA PF06160.12 KFP08179.1 - 0.014 13.6 4.4 0.53 8.4 0.4 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA HD_3 PF13023.6 KFP08179.1 - 0.042 13.8 0.2 0.042 13.8 0.2 2.3 2 1 1 3 3 3 0 HD domain Carn_acyltransf PF00755.20 KFP08179.1 - 0.27 9.8 1.6 2.8 6.4 0.0 2.5 3 0 0 3 3 3 0 Choline/Carnitine o-acyltransferase Jnk-SapK_ap_N PF09744.9 KFP08179.1 - 1.2 9.4 9.7 0.24 11.6 2.3 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 OmpH PF03938.14 KFP08179.1 - 1.5 9.2 9.4 1 9.7 0.4 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Occludin_ELL PF07303.13 KFP08179.1 - 4.9 7.9 6.4 2.7 8.8 1.0 2.5 2 0 0 2 2 2 0 Occludin homology domain Integrin_alpha2 PF08441.12 KFP08181.1 - 1.2e-91 308.0 0.0 2.5e-91 306.9 0.0 1.5 2 0 0 2 2 2 1 Integrin alpha FG-GAP PF01839.23 KFP08181.1 - 3.4e-25 87.8 21.0 2.2e-11 43.7 0.0 4.9 5 0 0 5 5 5 4 FG-GAP repeat VCBS PF13517.6 KFP08181.1 - 4e-12 46.5 15.0 7.2e-09 36.1 2.2 3.2 1 1 2 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.20 KFP08181.1 - 0.00091 19.0 0.2 0.0027 17.5 0.2 1.9 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region FG-GAP_2 PF14312.6 KFP08181.1 - 0.029 14.6 0.6 0.029 14.6 0.6 4.4 5 0 0 5 5 5 0 FG-GAP repeat Neuro_bHLH PF12533.8 KFP08182.1 - 2.9e-41 141.6 3.5 5.8e-41 140.6 3.5 1.5 1 0 0 1 1 1 1 Neuronal helix-loop-helix transcription factor HLH PF00010.26 KFP08182.1 - 6.6e-16 58.0 0.7 6.6e-16 58.0 0.7 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain CDC45 PF02724.14 KFP08182.1 - 6.8 4.9 7.3 8.5 4.5 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein PDEase_I PF00233.19 KFP08184.1 - 3.2e-83 279.1 4.6 3.2e-83 279.1 4.6 1.8 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.12 KFP08184.1 - 1.1e-31 108.5 0.1 2.9e-31 107.1 0.1 1.8 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal TEX19 PF15553.6 KFP08184.1 - 0.36 10.8 4.8 0.81 9.6 4.8 1.6 1 0 0 1 1 1 0 Testis-expressed protein 19 LSM PF01423.22 KFP08186.1 - 2.7e-20 71.8 1.1 2.9e-20 71.7 1.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFP08186.1 - 0.064 13.4 0.0 0.064 13.4 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.7 KFP08186.1 - 0.1 12.7 0.1 0.14 12.2 0.1 1.4 1 1 0 1 1 1 0 Scd6-like Sm domain Avl9 PF09794.9 KFP08187.1 - 1.1e-119 399.6 0.0 7.4e-114 380.4 0.0 2.1 2 0 0 2 2 2 2 Transport protein Avl9 SPA PF08616.10 KFP08187.1 - 1.4e-08 34.7 0.0 6.2e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DENN PF02141.21 KFP08187.1 - 0.00015 21.8 0.8 0.28 11.1 0.4 2.5 3 0 0 3 3 3 2 DENN (AEX-3) domain DUF2347 PF09804.9 KFP08187.1 - 0.0072 15.9 0.3 0.36 10.4 0.2 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) BACK PF07707.15 KFP08188.1 - 1.4e-20 73.2 1.5 2.6e-20 72.5 1.5 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFP08188.1 - 1.6e-18 66.2 2.0 0.00011 22.4 0.0 4.8 4 1 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 KFP08188.1 - 4.2e-18 64.7 23.3 1.4e-09 37.4 0.1 7.3 5 3 1 6 6 6 3 Kelch motif Kelch_2 PF07646.15 KFP08188.1 - 4.6e-09 35.9 5.0 0.037 14.0 0.0 5.2 4 1 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 KFP08188.1 - 4e-06 26.7 11.0 0.049 13.6 0.0 5.3 4 1 1 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP08188.1 - 5e-05 23.5 5.3 0.25 11.7 0.1 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP08188.1 - 0.099 12.7 3.8 6.5 6.9 0.1 3.8 4 0 0 4 4 4 0 Kelch motif baeRF_family5 PF18846.1 KFP08188.1 - 0.12 12.6 0.3 1.7 8.9 0.0 2.8 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 5 WYL_2 PF10902.8 KFP08188.1 - 0.18 12.2 2.2 22 5.5 0.0 3.6 4 0 0 4 4 4 0 WYL_2, Sm-like SH3 beta-barrel fold CENP-B_dimeris PF09026.10 KFP08189.1 - 4.4 7.8 12.5 13 6.2 12.5 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-CCHC_6 PF15288.6 KFP08190.1 - 0.0095 15.8 0.7 0.02 14.7 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle FKBP_C PF00254.28 KFP08191.1 - 4.8e-115 376.2 0.0 2.6e-27 95.0 0.0 5.1 5 0 0 5 5 5 4 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_1 PF00036.32 KFP08191.1 - 5.6e-09 34.9 1.0 0.00054 19.3 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFP08191.1 - 4.4e-06 27.1 0.3 0.032 14.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP08191.1 - 4.8e-05 22.6 0.7 0.089 12.3 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFP08191.1 - 6.2e-05 22.6 0.4 0.091 12.7 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KFP08191.1 - 0.00048 19.9 0.1 0.39 10.6 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair DUF2895 PF11444.8 KFP08191.1 - 0.0066 15.9 0.0 4.1 6.7 0.0 2.9 4 0 0 4 4 4 2 Protein of unknown function (DUF2895) UMPH-1 PF05822.12 KFP08192.1 - 2.9e-121 403.6 4.8 3.4e-121 403.4 4.8 1.0 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 KFP08192.1 - 0.0002 21.8 0.1 0.00041 20.8 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ACT_7 PF13840.6 KFP08192.1 - 0.0018 18.1 0.4 5.1 7.0 0.1 3.2 3 0 0 3 3 3 2 ACT domain NIF PF03031.18 KFP08192.1 - 0.011 15.6 0.1 0.74 9.6 0.0 2.7 1 1 0 2 2 2 0 NLI interacting factor-like phosphatase CIDE-N PF02017.15 KFP08192.1 - 0.012 15.6 0.1 0.28 11.2 0.0 2.6 2 0 0 2 2 2 0 CIDE-N domain PHTB1_N PF14727.6 KFP08193.1 - 1.4e-167 558.3 0.0 1.7e-167 558.0 0.0 1.1 1 0 0 1 1 1 1 PTHB1 N-terminus PHTB1_C PF14728.6 KFP08193.1 - 4.8e-156 519.6 3.8 6.3e-156 519.2 3.8 1.1 1 0 0 1 1 1 1 PTHB1 C-terminus VWD PF00094.25 KFP08195.1 - 8.7e-37 126.8 0.1 2.2e-36 125.5 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type D domain VWC PF00093.18 KFP08195.1 - 2.3e-23 82.2 146.3 8.8e-10 38.8 14.8 7.8 6 1 0 6 6 6 5 von Willebrand factor type C domain C8 PF08742.11 KFP08195.1 - 7.8e-15 55.1 13.6 7.8e-15 55.1 13.6 5.0 5 1 1 6 6 6 1 C8 domain TIL PF01826.17 KFP08195.1 - 1.6e-10 41.0 13.9 1.6e-10 41.0 13.9 9.2 4 2 4 8 8 8 1 Trypsin Inhibitor like cysteine rich domain TILa PF12714.7 KFP08195.1 - 0.0039 17.1 12.4 0.0039 17.1 12.4 9.1 6 4 3 9 9 9 3 TILa domain 7tm_1 PF00001.21 KFP08196.1 - 9.1e-38 130.1 18.0 6.4e-36 124.0 18.0 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) T-box PF00907.22 KFP08197.1 - 2.5e-71 239.7 0.0 2.8e-71 239.6 0.0 1.0 1 0 0 1 1 1 1 T-box ubiquitin PF00240.23 KFP08198.1 - 2.7e-08 33.4 0.1 4e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KFP08198.1 - 0.00074 20.0 0.0 0.0018 18.8 0.0 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain SOG2 PF10428.9 KFP08198.1 - 3.2 6.9 10.9 4.7 6.3 10.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Septin PF00735.18 KFP08199.1 - 3e-124 413.9 0.1 3e-124 413.9 0.1 1.9 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KFP08199.1 - 3.3e-07 30.4 1.1 8.1e-07 29.1 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP08199.1 - 2e-05 24.5 12.9 0.00025 21.0 0.4 3.4 3 1 0 3 3 3 2 RsgA GTPase AIG1 PF04548.16 KFP08199.1 - 0.001 18.4 0.0 0.001 18.4 0.0 2.5 3 0 0 3 3 3 1 AIG1 family AAA_16 PF13191.6 KFP08199.1 - 0.0075 16.7 0.4 0.028 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.27 KFP08199.1 - 0.0084 15.7 9.9 0.65 9.5 0.1 3.9 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KFP08199.1 - 0.017 15.4 1.4 0.036 14.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain Ras PF00071.22 KFP08199.1 - 0.019 14.6 1.5 0.039 13.5 0.0 2.2 2 0 0 2 2 2 0 Ras family FeoB_N PF02421.18 KFP08199.1 - 0.019 14.5 0.0 0.055 13.0 0.0 1.8 1 0 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.27 KFP08199.1 - 0.026 15.1 0.0 0.026 15.1 0.0 2.7 3 1 0 3 3 2 0 ABC transporter AAA_29 PF13555.6 KFP08199.1 - 0.043 13.6 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 KFP08199.1 - 0.054 13.7 0.0 0.23 11.7 0.0 2.1 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KFP08199.1 - 0.073 12.4 0.0 0.073 12.4 0.0 2.9 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region Fez1 PF06818.15 KFP08199.1 - 0.19 12.2 25.6 0.051 14.0 21.8 1.8 2 0 0 2 2 2 0 Fez1 Exonuc_VII_L PF02601.15 KFP08199.1 - 2.5 7.6 18.9 3.6 7.1 18.9 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF4140 PF13600.6 KFP08199.1 - 5.5 7.5 8.6 3.3e+02 1.8 10.8 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) HHH_3 PF12836.7 KFP08200.1 - 7.2e-42 141.5 0.1 1.3e-20 73.4 0.1 2.3 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH PF00633.23 KFP08200.1 - 4.1e-17 61.1 0.1 1.3e-06 27.9 0.0 3.7 3 0 0 3 3 3 3 Helix-hairpin-helix motif HHH_6 PF14579.6 KFP08200.1 - 7.9e-09 35.7 0.0 6.3e-05 23.2 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix motif T2SSK PF03934.13 KFP08200.1 - 3e-08 33.4 0.0 0.0017 17.8 0.0 2.2 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein K Exo_endo_phos PF03372.23 KFP08200.1 - 4e-08 33.1 0.0 8.1e-08 32.1 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HHH_2 PF12826.7 KFP08200.1 - 1.4e-07 31.5 0.1 0.022 14.8 0.0 2.9 3 0 0 3 3 3 2 Helix-hairpin-helix motif HHH_5 PF14520.6 KFP08200.1 - 1.2e-05 25.8 0.2 1.2 9.9 0.1 4.1 3 2 2 5 5 5 4 Helix-hairpin-helix domain PsbU PF06514.11 KFP08200.1 - 0.0085 16.1 0.0 0.93 9.5 0.0 2.4 2 0 0 2 2 2 1 Photosystem II 12 kDa extrinsic protein (PsbU) Exo_endo_phos_2 PF14529.6 KFP08200.1 - 0.051 13.4 0.3 0.17 11.8 0.3 2.0 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase DUF1704 PF08014.11 KFP08201.1 - 1.5e-16 60.4 0.0 2.3e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1704) Anillin_N PF16018.5 KFP08202.1 - 9.5e-39 131.9 12.1 8.5e-34 116.0 0.4 3.8 3 0 0 3 3 3 2 Anillin N-terminus Anillin PF08174.11 KFP08202.1 - 2e-38 132.0 0.1 5e-38 130.7 0.1 1.7 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.29 KFP08202.1 - 4e-18 65.8 1.4 9.8e-18 64.6 0.2 2.4 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KFP08202.1 - 0.018 15.5 0.1 0.072 13.5 0.1 2.1 1 0 0 1 1 1 0 Pleckstrin homology domain Lipase_GDSL PF00657.22 KFP08203.1 - 6.6e-14 52.4 0.0 1.1e-13 51.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Cu-binding_MopE PF11617.8 KFP08203.1 - 0.0027 17.9 0.6 0.0027 17.9 0.6 2.1 2 0 0 2 2 2 1 Putative metal-binding motif Lipase_GDSL_2 PF13472.6 KFP08203.1 - 0.0035 17.8 0.0 0.0081 16.6 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF3361 PF11841.8 KFP08204.1 - 6.4e-62 208.0 3.5 1.4e-61 207.0 3.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.13 KFP08204.1 - 1.3e-42 145.9 0.9 2.6e-42 144.9 0.9 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 KFP08204.1 - 1.2e-38 132.7 0.2 4.9e-38 130.7 0.0 2.2 3 0 0 3 3 3 1 Pleckstrin homology domain ZFYVE21_C PF16696.5 KFP08204.1 - 0.062 13.2 0.1 0.24 11.2 0.0 2.1 2 0 0 2 2 2 0 Zinc finger FYVE domain-containing protein 21 C-terminus FERM_N PF09379.10 KFP08204.1 - 0.078 12.9 0.0 0.71 9.9 0.0 2.5 3 0 0 3 3 3 0 FERM N-terminal domain GON PF08685.11 KFP08205.1 - 0.13 12.2 0.0 0.13 12.2 0.0 1.0 1 0 0 1 1 1 0 GON domain RVT_1 PF00078.27 KFP08206.1 - 0.011 15.2 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Thioredoxin PF00085.20 KFP08207.1 - 4.6e-06 26.5 0.2 7e-06 26.0 0.2 1.4 1 1 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 KFP08207.1 - 0.0088 15.8 0.0 0.0088 15.8 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KFP08207.1 - 0.061 13.3 0.0 0.061 13.3 0.0 1.1 1 0 0 1 1 1 0 AhpC/TSA family Glutaredoxin PF00462.24 KFP08207.1 - 0.1 12.8 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin NTR PF01759.21 KFP08208.1 - 1e-14 54.2 1.2 1.3e-14 53.8 0.2 1.7 1 1 1 2 2 2 1 UNC-6/NTR/C345C module Ependymin PF00811.18 KFP08209.1 - 3.5e-37 127.5 0.2 3.9e-37 127.3 0.2 1.0 1 0 0 1 1 1 1 Ependymin ANF_receptor PF01094.28 KFP08210.1 - 0.0039 16.4 0.0 0.0039 16.3 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Fumble PF03630.14 KFP08211.1 - 5.2e-117 390.7 0.0 6e-117 390.5 0.0 1.0 1 0 0 1 1 1 1 Fumble LRR_8 PF13855.6 KFP08212.1 - 2.6e-87 286.5 73.8 1.8e-14 53.2 1.8 9.2 4 3 5 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 KFP08212.1 - 4.4e-33 112.8 60.0 5.5e-05 23.4 1.7 11.2 8 3 2 12 12 12 11 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP08212.1 - 2e-32 111.8 9.9 3.9e-10 39.8 1.3 4.6 4 0 0 4 4 4 4 BspA type Leucine rich repeat region (6 copies) EGF PF00008.27 KFP08212.1 - 1e-26 92.9 106.0 9.5e-08 32.2 6.2 9.5 10 0 0 10 10 8 6 EGF-like domain LRR_9 PF14580.6 KFP08212.1 - 5.6e-22 78.1 19.7 1.6e-06 27.8 0.9 5.5 4 1 1 5 5 5 5 Leucine-rich repeat LRRNT PF01462.18 KFP08212.1 - 8.8e-19 66.7 44.0 6e-09 35.3 3.3 7.4 7 0 0 7 7 7 3 Leucine rich repeat N-terminal domain Laminin_G_2 PF02210.24 KFP08212.1 - 3.3e-18 66.5 0.1 5.3e-18 65.8 0.1 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFP08212.1 - 1.7e-14 54.2 0.1 2.7e-14 53.5 0.1 1.3 1 0 0 1 1 1 1 Laminin G domain hEGF PF12661.7 KFP08212.1 - 5.7e-13 49.0 94.2 2.9e-07 30.9 5.0 10.7 11 0 0 11 11 9 6 Human growth factor-like EGF LRRCT PF01463.24 KFP08212.1 - 8.3e-11 41.6 12.5 0.13 12.9 0.0 6.4 6 0 0 6 6 5 4 Leucine rich repeat C-terminal domain EGF_CA PF07645.15 KFP08212.1 - 0.011 15.9 5.3 0.011 15.9 5.3 9.7 7 1 3 10 10 8 0 Calcium-binding EGF domain EGF_3 PF12947.7 KFP08212.1 - 0.017 15.3 4.0 0.017 15.3 4.0 9.5 10 0 0 10 10 7 0 EGF domain Laminin_G_3 PF13385.6 KFP08212.1 - 0.024 14.8 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily LRR_1 PF00560.33 KFP08212.1 - 0.11 13.1 52.6 12 6.9 0.1 15.0 14 3 0 14 14 13 0 Leucine Rich Repeat TPKR_C2 PF16920.5 KFP08212.1 - 2.1 8.5 26.3 0.98 9.6 0.2 6.7 6 0 0 6 6 6 0 Tyrosine-protein kinase receptor C2 Ig-like domain HSP70 PF00012.20 KFP08213.1 - 6.7e-255 846.9 8.3 7.6e-255 846.7 8.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFP08213.1 - 2.1e-18 66.2 1.8 7e-16 58.0 0.5 2.5 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KFP08213.1 - 0.00019 21.3 0.1 0.00034 20.4 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KFP08213.1 - 0.0059 17.0 3.3 5.1 7.6 0.3 3.7 3 2 0 3 3 3 2 Cell division protein FtsA Vinculin PF01044.19 KFP08214.1 - 0 1038.2 37.6 4.2e-215 717.1 24.4 2.1 1 1 1 2 2 2 2 Vinculin family DUF4685 PF15737.5 KFP08214.1 - 0.17 12.3 1.7 33 4.9 0.3 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) Peptidase_C5 PF00770.18 KFP08214.1 - 0.19 11.4 0.0 0.43 10.2 0.0 1.5 1 0 0 1 1 1 0 Adenovirus endoprotease LRR_8 PF13855.6 KFP08215.1 - 3.3e-48 161.3 53.0 5.5e-16 58.1 6.7 5.1 2 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KFP08215.1 - 2.6e-25 88.0 37.3 3.7e-06 27.2 1.0 6.3 4 2 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP08215.1 - 2.7e-21 75.8 0.1 6.1e-10 39.2 0.0 3.4 3 1 1 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP08215.1 - 9.1e-12 44.8 10.4 0.0002 20.9 0.4 3.5 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 KFP08215.1 - 3.4e-08 32.9 34.9 0.98 10.2 0.2 9.9 10 0 0 10 10 10 4 Leucine Rich Repeat LRR_6 PF13516.6 KFP08215.1 - 0.0096 15.9 41.7 4.5 7.6 0.1 10.1 10 0 0 10 10 10 3 Leucine Rich repeat LRRNT PF01462.18 KFP08215.1 - 0.019 14.6 2.0 0.019 14.6 2.0 2.6 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain Fes1 PF08609.10 KFP08216.1 - 1.8e-05 25.5 1.6 1.8e-05 25.5 1.6 1.8 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 CDC14 PF08045.11 KFP08216.1 - 0.0014 17.8 0.5 0.0014 17.8 0.5 2.3 2 0 0 2 2 2 1 Cell division control protein 14, SIN component V-ATPase_H_C PF11698.8 KFP08216.1 - 0.013 15.6 2.2 0.22 11.6 0.3 2.9 1 1 2 3 3 3 0 V-ATPase subunit H MSP7_C PF12948.7 KFP08216.1 - 0.055 14.1 4.9 0.3 11.7 2.6 2.3 2 0 0 2 2 2 0 MSP7-like protein C-terminal domain DUF4704 PF15787.5 KFP08216.1 - 0.076 12.2 4.1 0.052 12.8 0.8 2.3 1 1 1 3 3 3 0 Domain of unknown function (DUF4704) SIR2_2 PF13289.6 KFP08216.1 - 0.087 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 SIR2-like domain MCU PF04678.13 KFP08216.1 - 6.4 6.8 8.0 3.9 7.5 1.7 2.6 2 1 0 2 2 2 0 Mitochondrial calcium uniporter RRM_1 PF00076.22 KFP08217.1 - 2.6e-09 36.7 0.0 0.00033 20.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP08217.1 - 7.3e-07 28.8 0.1 0.0096 15.5 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTU2 PF10288.9 KFP08217.1 - 1.6 9.0 0.0 1.6 9.0 0.0 4.0 3 1 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-C2H2_jaz PF12171.8 KFP08217.1 - 2.9 8.3 10.0 2.1 8.8 1.7 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PAM2 PF07145.15 KFP08218.1 - 3.2e-07 29.6 0.8 3.2e-07 29.6 0.8 1.9 2 0 0 2 2 2 1 Ataxin-2 C-terminal region DUF3911 PF13050.6 KFP08218.1 - 0.019 15.1 0.2 0.034 14.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3911) Xan_ur_permease PF00860.20 KFP08219.1 - 6.4e-87 291.8 22.9 8e-87 291.5 22.9 1.1 1 0 0 1 1 1 1 Permease family DUF3456 PF11938.8 KFP08220.1 - 4.6e-06 27.2 0.1 0.0026 18.3 0.0 2.8 1 1 1 2 2 2 2 TLR4 regulator and MIR-interacting MSAP DUF1977 PF09320.11 KFP08221.1 - 1.5e-25 89.5 4.3 1.5e-25 89.5 4.3 1.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 KFP08221.1 - 1.6e-25 89.0 0.2 4.3e-25 87.6 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain O-antigen_lig PF13425.6 KFP08221.1 - 0.033 13.0 1.9 0.049 12.4 1.9 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein GntP_permease PF02447.16 KFP08221.1 - 0.042 12.5 0.0 0.053 12.2 0.0 1.1 1 0 0 1 1 1 0 GntP family permease Folate_carrier PF01770.18 KFP08221.1 - 0.1 11.3 0.2 1.8 7.2 0.0 2.1 1 1 1 2 2 2 0 Reduced folate carrier Sel1 PF08238.12 KFP08222.1 - 5.7e-21 74.5 19.7 5.2e-08 33.3 0.2 5.4 5 0 0 5 5 5 4 Sel1 repeat TPR_6 PF13174.6 KFP08222.1 - 0.0017 18.9 8.2 1.9 9.3 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFP08222.1 - 0.024 14.7 17.3 0.8 10.0 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFP08222.1 - 0.046 13.6 4.3 0.79 9.7 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP08222.1 - 0.11 12.6 8.5 4.2 7.6 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFP08222.1 - 0.59 10.0 9.5 14 5.7 0.0 5.3 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFP08222.1 - 3.8 8.6 11.9 28 5.9 3.2 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 KFP08222.1 - 5.4 7.2 9.4 37 4.5 0.0 4.6 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 KFP08222.1 - 6.4 7.4 12.1 16 6.1 1.3 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat Cadherin PF00028.17 KFP08224.1 - 1.8e-117 384.1 2.7 1.4e-22 79.9 0.0 7.4 7 0 0 7 7 7 7 Cadherin domain Protocadherin PF08374.11 KFP08224.1 - 7.9e-82 274.4 1.2 1.5e-81 273.6 1.2 1.5 1 0 0 1 1 1 1 Protocadherin Cadherin_2 PF08266.12 KFP08224.1 - 3e-14 52.6 0.0 1.6e-05 24.7 0.0 6.1 6 1 0 6 6 6 3 Cadherin-like Cadherin_3 PF16184.5 KFP08224.1 - 1.4e-07 31.5 5.8 1.2 9.2 0.1 6.0 6 0 0 6 6 6 3 Cadherin-like He_PIG PF05345.12 KFP08224.1 - 0.0032 17.6 0.3 4.1 7.7 0.0 4.5 5 0 0 5 5 5 1 Putative Ig domain TMEM154 PF15102.6 KFP08224.1 - 0.015 15.2 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family Syndecan PF01034.20 KFP08224.1 - 0.076 12.9 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain Mid2 PF04478.12 KFP08224.1 - 0.083 12.7 0.1 0.32 10.8 0.0 2.0 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor EphA2_TM PF14575.6 KFP08224.1 - 0.09 13.7 0.0 0.21 12.5 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MLANA PF14991.6 KFP08224.1 - 0.11 12.8 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A FlgD_ig PF13860.6 KFP08224.1 - 0.2 11.5 1.7 1.6 8.7 0.1 3.3 3 0 0 3 3 3 0 FlgD Ig-like domain RhoGAP PF00620.27 KFP08226.1 - 1.2e-45 155.1 0.1 2.4e-45 154.1 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KFP08226.1 - 6.2e-26 91.0 0.2 6.7e-06 26.6 0.1 4.6 4 0 0 4 4 4 4 PH domain ArfGap PF01412.18 KFP08226.1 - 6.1e-15 55.3 0.0 1.4e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SAM_2 PF07647.17 KFP08226.1 - 6.9e-12 45.3 0.0 3.9e-11 42.9 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) RA PF00788.23 KFP08226.1 - 2.8e-11 43.9 0.1 6.9e-11 42.6 0.1 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.30 KFP08226.1 - 1.1e-10 41.8 0.0 3.7e-10 40.1 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH_6 PF15406.6 KFP08226.1 - 0.00073 19.8 0.0 0.0025 18.1 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFP08226.1 - 0.0084 16.5 2.3 0.45 11.0 0.1 3.9 3 1 0 4 4 4 1 Pleckstrin homology domain PH_8 PF15409.6 KFP08226.1 - 0.013 15.7 0.0 0.082 13.2 0.0 2.4 3 0 0 3 3 3 0 Pleckstrin homology domain PH_3 PF14593.6 KFP08226.1 - 0.029 14.4 0.5 0.2 11.8 0.1 2.6 3 0 0 3 3 3 0 PH domain 7tm_1 PF00001.21 KFP08227.1 - 1.6e-30 106.4 9.4 3.9e-30 105.0 9.4 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TatC PF00902.18 KFP08227.1 - 8.8e-05 22.4 5.1 0.00013 21.8 5.1 1.4 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) MatE PF01554.18 KFP08227.1 - 0.025 14.2 6.3 0.06 13.0 6.1 1.7 1 1 0 1 1 1 0 MatE 7TM_GPCR_Srw PF10324.9 KFP08227.1 - 0.063 12.6 5.1 0.16 11.2 1.3 2.1 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw RELT PF12606.8 KFP08228.1 - 5.9e-24 82.8 3.3 1.2e-23 81.8 3.3 1.6 1 0 0 1 1 1 1 Tumour necrosis factor receptor superfamily member 19 SieB PF14163.6 KFP08228.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Super-infection exclusion protein B Hist_deacetyl PF00850.19 KFP08229.1 - 2.2e-81 273.7 0.1 3.2e-81 273.2 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain RrnaAD PF00398.20 KFP08231.1 - 5.9e-55 186.2 0.0 7.1e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KFP08231.1 - 1.5e-07 32.0 0.0 4.9e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP08231.1 - 9.5e-05 23.0 0.0 0.00069 20.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP08231.1 - 0.00099 19.8 0.0 0.0028 18.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP08231.1 - 0.0056 16.5 0.0 0.0084 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP08231.1 - 0.0062 16.3 0.0 0.012 15.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFP08231.1 - 0.0097 15.7 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 KFP08231.1 - 0.019 14.9 0.0 0.042 13.8 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.18 KFP08231.1 - 0.027 14.1 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.17 KFP08231.1 - 0.032 13.7 0.0 0.076 12.5 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase DREV PF05219.12 KFP08231.1 - 0.05 12.7 0.0 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 DREV methyltransferase MTS PF05175.14 KFP08231.1 - 0.066 12.8 0.0 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_28 PF02636.17 KFP08231.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 KFP08231.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family IBN_N PF03810.19 KFP08232.1 - 4.2e-20 71.4 1.6 5e-19 68.0 0.0 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KFP08232.1 - 0.0084 16.5 0.0 0.078 13.4 0.0 2.6 2 1 1 3 3 3 1 HEAT repeats MOR2-PAG1_C PF14225.6 KFP08232.1 - 0.017 15.0 2.3 0.68 9.7 0.7 2.9 2 0 0 2 2 2 0 Cell morphogenesis C-terminal Xpo1 PF08389.12 KFP08232.1 - 0.034 14.2 9.3 0.051 13.6 0.0 4.6 5 0 0 5 5 5 0 Exportin 1-like protein HEAT PF02985.22 KFP08232.1 - 0.13 12.5 0.2 58 4.3 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat Yae1_N PF09811.9 KFP08234.1 - 2.2e-16 59.3 57.0 1.8e+04 -21.8 57.0 5.4 1 1 0 1 1 1 0 Essential protein Yae1, N terminal 7tm_1 PF00001.21 KFP08235.1 - 3.9e-84 282.1 4.4 4.6e-84 281.8 4.4 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP08235.1 - 1.1e-13 51.1 1.0 2e-13 50.3 1.0 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP08235.1 - 9.5e-05 22.1 3.6 9.5e-05 22.1 3.6 2.5 2 2 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP08235.1 - 0.00018 21.3 4.9 0.011 15.5 0.9 3.1 3 0 0 3 3 3 1 Olfactory receptor Cyt_bd_oxida_II PF02322.15 KFP08235.1 - 0.013 14.9 0.1 0.013 14.9 0.1 2.6 3 0 0 3 3 3 0 Cytochrome bd terminal oxidase subunit II Sld5 PF05916.11 KFP08236.1 - 0.043 14.3 0.2 0.067 13.7 0.2 1.3 1 0 0 1 1 1 0 GINS complex protein Med21 PF11221.8 KFP08236.1 - 0.064 13.5 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Subunit 21 of Mediator complex zf-CCHC_3 PF13917.6 KFP08237.1 - 4e-08 33.1 0.2 4.3e-08 33.0 0.2 1.2 1 1 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KFP08237.1 - 0.036 14.1 2.7 0.049 13.7 2.7 1.2 1 0 0 1 1 1 0 Zinc knuckle CpXC PF14353.6 KFP08237.1 - 0.048 13.7 0.1 0.049 13.7 0.1 1.1 1 0 0 1 1 1 0 CpXC protein Pro_isomerase PF00160.21 KFP08238.1 - 1.5e-50 171.6 0.1 3.1e-50 170.5 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KFP08238.1 - 4.7e-11 43.1 2.6 0.065 14.1 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP08238.1 - 0.00088 19.5 0.0 1.4 9.2 0.0 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF505 PF04458.12 KFP08238.1 - 0.014 13.8 0.0 0.021 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF505) Ge1_WD40 PF16529.5 KFP08238.1 - 0.079 11.9 0.4 22 3.9 0.0 3.6 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Arf PF00025.21 KFP08239.1 - 8.1e-71 237.1 0.5 1.7e-70 236.0 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 KFP08239.1 - 2.7e-14 53.4 0.2 3.4e-13 49.8 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP08239.1 - 1.1e-11 44.7 0.0 2e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFP08239.1 - 2.8e-11 43.2 0.0 5.5e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFP08239.1 - 2.5e-10 40.1 0.1 6.4e-08 32.1 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit zf-B_box PF00643.24 KFP08239.1 - 3.3e-07 30.4 5.4 3.3e-07 30.4 5.4 4.0 4 0 0 4 4 3 2 B-box zinc finger zf-RING_UBOX PF13445.6 KFP08239.1 - 1.1e-06 28.6 5.1 1.1e-06 28.6 5.1 3.0 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP08239.1 - 1.7e-06 27.8 1.9 1.7e-06 27.8 1.9 4.2 3 1 0 3 3 2 1 zinc-RING finger domain Gtr1_RagA PF04670.12 KFP08239.1 - 1.9e-06 27.4 0.0 4.4e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region zf-RING_2 PF13639.6 KFP08239.1 - 3.4e-05 24.1 3.0 3.4e-05 24.1 3.0 4.3 4 0 0 4 4 4 1 Ring finger domain MMR_HSR1 PF01926.23 KFP08239.1 - 0.00018 21.5 0.1 0.00072 19.6 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase zf-C3HC4 PF00097.25 KFP08239.1 - 0.00037 20.3 1.3 0.00037 20.3 1.3 3.7 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP08239.1 - 0.0068 16.2 3.6 0.0068 16.2 3.6 3.6 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP08239.1 - 0.007 16.2 3.2 0.007 16.2 3.2 3.2 4 0 0 4 4 3 1 Prokaryotic RING finger family 4 Thymidylate_kin PF02223.17 KFP08239.1 - 0.16 11.7 1.1 2.9 7.5 0.1 2.4 2 0 0 2 2 2 0 Thymidylate kinase FemAB PF02388.16 KFP08239.1 - 0.43 9.4 1.4 0.42 9.4 0.3 1.5 2 0 0 2 2 2 0 FemAB family APOBEC3 PF18771.1 KFP08240.1 - 0.036 14.2 0.0 0.086 13.0 0.0 1.8 1 1 0 1 1 1 0 APOBEC3 DUF974 PF06159.13 KFP08241.1 - 1.9e-84 283.3 0.5 2.5e-84 282.9 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Transglut_C PF00927.22 KFP08241.1 - 0.0033 17.6 0.2 0.052 13.7 0.0 2.8 2 1 0 3 3 3 1 Transglutaminase family, C-terminal ig like domain Trs65 PF12735.7 KFP08241.1 - 0.013 15.0 0.0 3.6 6.9 0.0 3.1 2 1 1 3 3 3 0 TRAPP trafficking subunit Trs65 TPR_1 PF00515.28 KFP08242.1 - 8.6e-30 101.3 10.8 8.9e-10 38.0 1.6 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFP08242.1 - 3.7e-23 80.9 11.2 3.9e-09 36.0 1.0 4.1 2 1 2 4 4 4 3 TPR repeat TPR_2 PF07719.17 KFP08242.1 - 5.4e-23 79.2 6.8 7.4e-07 28.8 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFP08242.1 - 3.6e-19 67.3 8.7 4.8e-06 26.4 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat SGTA_dimer PF16546.5 KFP08242.1 - 1.7e-18 66.1 1.3 6.9e-16 57.8 0.0 3.2 3 0 0 3 3 3 1 Homodimerisation domain of SGTA TPR_7 PF13176.6 KFP08242.1 - 3e-15 55.1 0.4 0.00016 21.5 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFP08242.1 - 8.9e-15 53.9 5.5 8.8e-08 32.0 1.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP08242.1 - 3.4e-10 39.9 0.1 0.04 14.7 0.0 3.9 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFP08242.1 - 7.3e-10 39.0 2.6 3.9e-05 23.9 0.2 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFP08242.1 - 3.2e-09 37.3 0.1 2.7e-05 24.7 0.0 2.3 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFP08242.1 - 5e-09 36.2 0.1 5e-06 26.6 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP08242.1 - 5.6e-09 36.4 1.6 6.6e-05 23.4 0.5 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFP08242.1 - 6.2e-06 25.9 4.0 0.19 11.6 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TOM20_plant PF06552.12 KFP08242.1 - 2.1e-05 24.3 3.5 0.014 15.2 0.3 3.3 2 1 1 3 3 2 2 Plant specific mitochondrial import receptor subunit TOM20 SHNi-TPR PF10516.9 KFP08242.1 - 3.1e-05 23.3 0.2 0.68 9.4 0.1 3.4 3 0 0 3 3 3 1 SHNi-TPR TPR_6 PF13174.6 KFP08242.1 - 6.4e-05 23.3 1.1 1.5 9.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF627 PF04781.12 KFP08242.1 - 0.00018 21.5 1.0 0.0022 18.0 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF627) Fis1_TPR_C PF14853.6 KFP08242.1 - 0.0006 19.8 9.6 0.096 12.8 0.4 3.8 3 1 1 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 KFP08242.1 - 0.0024 18.3 0.3 0.014 15.8 0.1 2.0 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_15 PF13429.6 KFP08242.1 - 0.004 16.4 0.3 2.9 7.0 0.0 2.8 1 1 2 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 KFP08242.1 - 0.0056 16.7 12.7 0.54 10.4 0.2 4.2 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 KFP08242.1 - 0.0061 16.8 3.8 0.018 15.2 3.8 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 XPC-binding PF09280.11 KFP08242.1 - 0.019 14.7 10.7 0.26 11.0 3.2 2.7 2 0 0 2 2 2 0 XPC-binding domain GerD PF17898.1 KFP08242.1 - 0.034 14.1 0.2 0.55 10.2 0.1 2.5 2 0 0 2 2 2 0 Spore germination GerD central core domain FAT PF02259.23 KFP08242.1 - 0.054 12.7 0.3 0.085 12.1 0.3 1.4 1 0 0 1 1 1 0 FAT domain Barstar PF01337.18 KFP08242.1 - 0.06 13.4 1.0 0.14 12.2 0.1 2.1 3 0 0 3 3 1 0 Barstar (barnase inhibitor) T3SSipB PF16535.5 KFP08242.1 - 0.11 12.9 0.5 0.11 12.9 0.5 2.3 2 1 1 3 3 3 0 Type III cell invasion protein SipB DUF3856 PF12968.7 KFP08242.1 - 0.18 11.8 1.5 35 4.5 1.5 3.1 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) STI1 PF17830.1 KFP08242.1 - 1.8 8.6 8.3 0.27 11.2 2.2 2.5 2 0 0 2 2 2 0 STI1 domain Peptidase_M3 PF01432.20 KFP08243.1 - 2.3e-152 508.4 0.2 3.2e-152 508.0 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M3 LRR_8 PF13855.6 KFP08244.1 - 2e-37 126.8 32.6 8.2e-09 35.1 1.9 7.4 4 1 6 10 10 10 9 Leucine rich repeat LRR_4 PF12799.7 KFP08244.1 - 1.9e-26 91.7 43.1 0.0009 19.6 2.0 9.9 4 2 5 10 10 10 9 Leucine Rich repeats (2 copies) PDZ PF00595.24 KFP08244.1 - 1.6e-13 50.8 0.1 3.7e-13 49.6 0.1 1.7 1 0 0 1 1 1 1 PDZ domain LRR_5 PF13306.6 KFP08244.1 - 1.1e-06 28.7 4.8 0.008 16.1 0.3 3.8 2 1 3 5 5 5 4 BspA type Leucine rich repeat region (6 copies) PDZ_6 PF17820.1 KFP08244.1 - 7.2e-06 25.7 0.0 1.9e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP08244.1 - 8.1e-05 22.9 0.1 0.00083 19.6 0.0 2.7 2 0 0 2 2 2 1 PDZ domain CDC37_C PF08564.10 KFP08244.1 - 0.0023 18.0 0.9 0.0023 18.0 0.9 2.7 2 0 0 2 2 2 1 Cdc37 C terminal domain LRR_1 PF00560.33 KFP08244.1 - 0.038 14.5 29.1 13 6.8 0.1 11.4 11 1 0 11 11 11 0 Leucine Rich Repeat CCDC74_C PF14917.6 KFP08244.1 - 0.061 13.8 0.1 0.061 13.8 0.1 2.9 3 0 0 3 3 3 0 Coiled coil protein 74, C terminal DUF240 PF03086.14 KFP08244.1 - 0.07 13.1 0.1 0.33 10.9 0.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF240) RsmF_methylt_CI PF17126.5 KFP08244.1 - 0.076 13.1 0.4 6.5 6.9 0.0 4.0 4 0 0 4 4 4 0 RsmF rRNA methyltransferase first C-terminal domain LRR_6 PF13516.6 KFP08244.1 - 0.64 10.2 22.5 13 6.2 0.1 7.8 8 0 0 8 8 7 0 Leucine Rich repeat RRM_1 PF00076.22 KFP08245.1 - 1.9e-13 50.0 0.1 3.4e-13 49.2 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP08245.1 - 0.0057 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1908 PF08926.11 KFP08247.1 - 3e-133 443.3 1.7 3e-133 443.3 1.7 3.2 4 0 0 4 4 3 1 Domain of unknown function (DUF1908) Pkinase PF00069.25 KFP08247.1 - 2.2e-61 207.5 0.0 4.1e-61 206.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP08247.1 - 1e-26 93.8 0.0 2.4e-26 92.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase PDZ_6 PF17820.1 KFP08247.1 - 4.2e-11 42.5 0.4 1.1e-10 41.2 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 KFP08247.1 - 5.4e-10 39.5 0.1 1.1e-09 38.5 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP08247.1 - 2.4e-06 27.8 0.0 6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain APH PF01636.23 KFP08247.1 - 8.2e-06 25.9 0.0 0.03 14.3 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KFP08247.1 - 0.00059 19.2 0.0 0.0018 17.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KFP08247.1 - 0.0091 15.6 0.1 0.023 14.3 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Tricorn_PDZ PF14685.6 KFP08247.1 - 0.019 14.9 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain Haspin_kinase PF12330.8 KFP08247.1 - 0.023 13.6 0.0 0.064 12.2 0.0 1.7 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KFP08247.1 - 0.066 12.0 0.0 0.19 10.5 0.0 1.7 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KFP08247.1 - 0.11 11.8 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PI3K_P85_iSH2 PF16454.5 KFP08249.1 - 1.1e-62 210.4 21.4 2e-62 209.5 21.4 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SH2 PF00017.24 KFP08249.1 - 1.3e-42 143.7 0.1 1.1e-21 76.6 0.0 2.6 2 0 0 2 2 2 2 SH2 domain RhoGAP PF00620.27 KFP08249.1 - 4.7e-33 114.2 0.1 4.7e-33 114.2 0.1 2.3 3 0 0 3 3 2 1 RhoGAP domain SH3_1 PF00018.28 KFP08249.1 - 8.8e-06 25.2 1.5 0.00059 19.4 0.1 2.9 2 0 0 2 2 2 1 SH3 domain AAA_13 PF13166.6 KFP08249.1 - 7.4e-05 21.6 12.6 0.00012 21.0 12.6 1.2 1 0 0 1 1 1 1 AAA domain DUF4201 PF13870.6 KFP08249.1 - 0.00025 20.8 12.4 0.0016 18.2 1.7 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) SH3_9 PF14604.6 KFP08249.1 - 0.0014 18.5 0.6 0.0035 17.2 0.6 1.8 1 1 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP08249.1 - 0.0022 17.7 0.0 0.0077 15.9 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain Laminin_I PF06008.14 KFP08249.1 - 0.0041 16.9 9.1 0.0077 16.0 9.1 1.3 1 0 0 1 1 1 1 Laminin Domain I Mod_r PF07200.13 KFP08249.1 - 0.017 15.2 18.8 0.35 11.0 2.8 2.6 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein PI_PP_I PF18363.1 KFP08249.1 - 0.038 14.2 1.6 0.4 10.9 1.6 2.7 1 1 0 1 1 1 0 Phosphoinositide phosphatase insertion domain Transcrip_act PF04949.13 KFP08249.1 - 0.87 9.5 14.1 0.68 9.8 6.3 3.0 1 1 2 3 3 3 0 Transcriptional activator Exonuc_VII_L PF02601.15 KFP08249.1 - 1.4 8.4 7.7 2.7 7.5 7.7 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Occludin_ELL PF07303.13 KFP08249.1 - 2.4 8.9 20.0 7.8 7.3 3.0 2.8 1 1 1 2 2 2 0 Occludin homology domain DUF2203 PF09969.9 KFP08249.1 - 3.2 8.5 9.4 1.1 10.0 1.3 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Bap31_Bap29_C PF18035.1 KFP08249.1 - 5.8 7.0 6.5 0.99 9.5 0.5 2.7 2 1 1 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain BRE1 PF08647.11 KFP08249.1 - 7 6.8 15.1 0.31 11.1 3.8 2.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Seryl_tRNA_N PF02403.22 KFP08249.1 - 7.4 6.9 11.6 7.3 6.9 6.4 3.3 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Troponin PF00992.20 KFP08249.1 - 9.2 6.6 18.3 1.8 8.8 14.2 1.9 1 1 1 2 2 2 0 Troponin Cation_efflux PF01545.21 KFP08250.1 - 1.5e-44 152.1 12.2 1.5e-44 152.1 12.2 3.2 3 1 0 3 3 3 1 Cation efflux family DUF2946 PF11162.8 KFP08250.1 - 5.7 7.6 10.1 18 6.0 10.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) S36_mt PF10937.8 KFP08251.1 - 0.024 16.2 0.1 0.028 16.0 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein S36, mitochondrial Pkinase PF00069.25 KFP08252.1 - 3.3e-71 239.7 0.0 3.8e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP08252.1 - 3.4e-29 101.9 0.0 4.4e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP08252.1 - 2.8e-05 23.6 0.1 0.00045 19.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 KFP08252.1 - 0.00012 21.3 0.2 0.0015 17.7 0.1 2.0 2 0 0 2 2 2 1 Seadornavirus VP7 APH PF01636.23 KFP08252.1 - 0.0069 16.3 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFP08252.1 - 0.024 13.6 0.8 0.066 12.1 0.8 1.7 1 1 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KFP08252.1 - 0.047 13.3 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KFP08252.1 - 0.082 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Serinc PF03348.15 KFP08253.1 - 7e-164 545.8 32.2 7.9e-164 545.6 32.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF5336 PF17270.2 KFP08253.1 - 0.95 9.1 5.9 1.5 8.4 4.3 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5336) DUF3593 PF12159.8 KFP08253.1 - 3.4 7.7 15.1 1.4 9.0 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3593) Tom37 PF10568.9 KFP08254.1 - 3.2e-27 95.3 0.1 5.6e-27 94.5 0.1 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 KFP08254.1 - 2.8e-23 81.5 0.8 6.9e-23 80.2 0.3 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KFP08254.1 - 4.7e-10 40.1 0.0 9e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 KFP08254.1 - 5.9e-07 29.4 0.0 1.8e-06 27.8 0.1 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain fn3 PF00041.21 KFP08255.1 - 1.8e-12 47.4 0.0 2.4e-06 27.8 0.0 2.8 2 0 0 2 2 2 2 Fibronectin type III domain SPRY PF00622.28 KFP08255.1 - 2.6e-05 24.3 0.0 6.5e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 SPRY domain INCA1 PF15142.6 KFP08256.1 - 0.091 12.8 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 INCA1 PAP_assoc PF03828.19 KFP08257.1 - 4.5e-16 58.8 0.1 2e-15 56.8 0.0 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KFP08257.1 - 0.00012 22.3 0.0 0.00024 21.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain WH1 PF00568.23 KFP08258.1 - 7e-35 119.3 0.3 1.3e-34 118.4 0.3 1.5 1 0 0 1 1 1 1 WH1 domain TMF_TATA_bd PF12325.8 KFP08258.1 - 0.00049 20.3 18.3 0.00049 20.3 18.3 3.0 2 1 1 3 3 3 1 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 KFP08258.1 - 0.005 16.9 14.6 0.069 13.2 6.8 3.2 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) GAS PF13851.6 KFP08258.1 - 0.005 16.2 18.6 0.005 16.2 18.6 2.6 2 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.9 KFP08258.1 - 0.011 16.0 7.4 0.011 16.0 7.4 3.4 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6_N PF17675.1 KFP08258.1 - 0.017 15.7 22.7 0.017 15.7 22.7 3.2 1 1 1 2 2 2 0 Apg6 coiled-coil region PKcGMP_CC PF16808.5 KFP08258.1 - 0.024 14.5 2.7 0.024 14.5 2.7 3.8 4 1 0 4 4 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase IFT57 PF10498.9 KFP08258.1 - 0.027 13.5 25.9 0.058 12.4 25.9 1.6 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DMPK_coil PF08826.10 KFP08258.1 - 0.027 14.6 9.6 0.027 14.6 9.6 3.4 2 1 1 3 3 3 0 DMPK coiled coil domain like Nsp1_C PF05064.13 KFP08258.1 - 0.035 13.9 23.4 0.38 10.6 11.1 2.7 1 1 1 2 2 2 0 Nsp1-like C-terminal region NPV_P10 PF05531.12 KFP08258.1 - 0.11 12.9 11.8 0.35 11.4 0.8 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein FUSC PF04632.12 KFP08258.1 - 0.12 10.9 8.6 0.16 10.5 8.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ATG16 PF08614.11 KFP08258.1 - 0.25 11.6 39.4 1.6 8.9 22.0 2.9 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) FPP PF05911.11 KFP08258.1 - 0.28 9.3 33.5 0.3 9.2 22.8 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Laminin_II PF06009.12 KFP08258.1 - 0.32 11.0 20.7 0.075 13.0 9.9 2.9 2 1 1 3 3 3 0 Laminin Domain II Phage_GP20 PF06810.11 KFP08258.1 - 0.36 10.6 23.8 2.8 7.7 15.6 3.7 1 1 2 3 3 3 0 Phage minor structural protein GP20 HemX PF04375.14 KFP08258.1 - 0.48 9.7 24.3 0.17 11.2 10.0 2.5 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4164 PF13747.6 KFP08258.1 - 0.48 10.7 24.2 0.05 13.9 12.4 3.4 2 1 2 4 4 3 0 Domain of unknown function (DUF4164) CALCOCO1 PF07888.11 KFP08258.1 - 0.61 8.9 31.4 0.26 10.1 26.2 2.4 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF812 PF05667.11 KFP08258.1 - 0.76 8.6 30.9 1.3 7.8 30.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF2968 PF11180.8 KFP08258.1 - 1 9.0 27.8 0.88 9.2 5.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) Prominin PF05478.11 KFP08258.1 - 1.1 7.1 10.4 2.1 6.2 10.4 1.6 1 0 0 1 1 1 0 Prominin FlaC_arch PF05377.11 KFP08258.1 - 1.7 9.1 17.0 15 6.0 1.8 4.4 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) DUF948 PF06103.11 KFP08258.1 - 1.9 8.8 11.4 5 7.4 2.4 3.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.6 KFP08258.1 - 2.3 7.5 21.8 3.4 6.9 20.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DHR10 PF18595.1 KFP08258.1 - 2.3 8.3 42.0 0.84 9.7 20.6 3.6 2 1 2 4 4 4 0 Designed helical repeat protein 10 domain DUF489 PF04356.12 KFP08258.1 - 2.4 8.2 10.9 1.1 9.3 6.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF489) DUF3461 PF11944.8 KFP08258.1 - 2.6 8.2 14.9 0.24 11.6 4.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) Fib_alpha PF08702.10 KFP08258.1 - 2.8 8.1 19.8 1.5 9.0 11.0 2.7 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family kleA_kleC PF17383.2 KFP08258.1 - 2.9 8.3 9.4 2.3 8.6 1.4 3.0 2 1 0 2 2 2 0 Uncharacterized KorC regulated protein A Fzo_mitofusin PF04799.13 KFP08258.1 - 3.1 7.3 19.9 3 7.4 11.5 2.9 1 1 2 3 3 3 0 fzo-like conserved region Leu_zip PF15294.6 KFP08258.1 - 3.8 7.0 28.6 1.8 8.0 25.3 2.1 1 1 1 2 2 2 0 Leucine zipper HMMR_N PF15905.5 KFP08258.1 - 4.1 6.8 36.4 0.066 12.7 28.3 2.0 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal TMF_DNA_bd PF12329.8 KFP08258.1 - 5.6 7.0 37.1 0.49 10.4 7.6 3.8 2 1 2 4 4 3 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 KFP08258.1 - 5.9 7.0 35.4 0.2 11.7 12.5 2.8 2 1 1 3 3 2 0 Afadin- and alpha -actinin-Binding NAM-associated PF14303.6 KFP08258.1 - 6.3 7.5 18.4 2e+02 2.6 18.4 2.4 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain CENP-F_leu_zip PF10473.9 KFP08258.1 - 6.6 6.7 36.6 0.56 10.2 26.5 3.4 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fmp27_WPPW PF10359.9 KFP08258.1 - 6.6 5.5 19.6 1.4 7.7 15.5 1.8 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DivIC PF04977.15 KFP08258.1 - 6.9 6.5 34.1 0.36 10.6 4.0 4.6 3 2 1 4 4 3 0 Septum formation initiator XhlA PF10779.9 KFP08258.1 - 7.4 6.9 18.2 1.2 9.4 3.2 3.5 2 1 2 4 4 4 0 Haemolysin XhlA OmpH PF03938.14 KFP08258.1 - 8.1 6.8 33.0 0.24 11.7 18.4 3.4 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) Spc7 PF08317.11 KFP08258.1 - 8.1 5.2 35.6 0.22 10.4 20.6 2.6 2 1 1 3 3 3 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.22 KFP08258.1 - 8.6 6.6 28.9 0.16 12.2 9.4 3.0 2 1 1 3 3 2 0 Seryl-tRNA synthetase N-terminal domain Syntaxin-6_N PF09177.11 KFP08258.1 - 8.7 7.0 19.0 1.6 9.3 8.9 3.3 2 1 1 3 3 3 0 Syntaxin 6, N-terminal FTCD_C PF04961.12 KFP08258.1 - 8.9 6.0 10.4 1.8 8.3 3.0 2.5 3 0 0 3 3 2 0 Formiminotransferase-cyclodeaminase DUF2203 PF09969.9 KFP08258.1 - 9.7 6.9 18.2 0.55 11.0 7.4 3.0 1 1 2 4 4 4 0 Uncharacterized conserved protein (DUF2203) JMY PF15871.5 KFP08259.1 - 8e-164 545.1 25.2 8e-164 545.1 25.2 2.4 2 0 0 2 2 2 1 Junction-mediating and -regulatory protein WH2 PF02205.20 KFP08259.1 - 0.0018 18.0 0.2 0.0018 18.0 0.2 3.4 4 0 0 4 4 4 1 WH2 motif GAT PF03127.14 KFP08259.1 - 0.34 11.2 8.6 0.16 12.3 0.8 3.2 3 0 0 3 3 3 0 GAT domain RVT_1 PF00078.27 KFP08260.1 - 0.069 12.7 0.0 0.18 11.3 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) S-methyl_trans PF02574.16 KFP08261.1 - 6.8e-49 167.1 0.0 8.6e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase GCV_T PF01571.21 KFP08262.1 - 2.7e-71 240.0 0.0 3.8e-71 239.5 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 KFP08262.1 - 5.6e-65 220.2 0.1 8e-65 219.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T_C PF08669.11 KFP08262.1 - 2.4e-21 75.4 0.0 5.4e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 KFP08262.1 - 6.8e-13 48.8 0.1 1.4e-12 47.8 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain Pyr_redox_3 PF13738.6 KFP08262.1 - 1.3e-07 31.1 0.0 6.3e-05 22.4 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SoxG PF04268.12 KFP08262.1 - 1.9e-07 31.3 0.0 4.5e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 Sarcosine oxidase, gamma subunit family FAD_binding_2 PF00890.24 KFP08262.1 - 3.7e-05 23.0 0.1 8.1e-05 21.9 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KFP08262.1 - 9.4e-05 22.6 0.9 0.00065 19.9 0.6 2.4 1 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFP08262.1 - 0.00047 19.5 0.2 0.00085 18.6 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KFP08262.1 - 0.0022 17.3 0.3 0.0037 16.6 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFP08262.1 - 0.0039 16.5 0.0 0.0067 15.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFP08262.1 - 0.02 14.0 0.1 0.031 13.3 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 KFP08262.1 - 0.021 14.5 0.1 0.046 13.4 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 KFP08262.1 - 0.032 14.8 0.2 0.17 12.5 0.1 2.3 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFP08262.1 - 0.066 11.9 0.1 0.68 8.6 0.1 2.4 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_9 PF13454.6 KFP08262.1 - 0.069 13.1 0.3 0.28 11.2 0.1 2.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KFP08262.1 - 0.16 12.2 0.0 0.97 9.7 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain Sulfatase PF00884.23 KFP08263.1 - 3.5e-49 167.9 0.0 4.5e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF1501 PF07394.12 KFP08263.1 - 0.0065 15.6 0.0 0.031 13.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1501) Sulfatase_C PF14707.6 KFP08263.1 - 0.014 16.1 0.0 0.053 14.3 0.0 1.8 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 KFP08263.1 - 0.039 13.5 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 KFP08263.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function L_HMGIC_fpl PF10242.9 KFP08264.1 - 3e-64 216.6 8.3 3.5e-64 216.4 8.3 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 KFP08264.1 - 5.5e-06 26.3 6.0 1.5e-05 24.9 6.0 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Nucleos_tra2_C PF07662.13 KFP08264.1 - 0.0049 16.7 0.6 0.0049 16.7 0.6 1.8 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Claudin_3 PF06653.11 KFP08264.1 - 0.0071 16.3 5.8 0.0071 16.3 5.8 1.7 2 0 0 2 2 2 1 Tight junction protein, Claudin-like PMP22_Claudin PF00822.20 KFP08264.1 - 0.11 12.4 16.8 0.25 11.2 16.8 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF4245 PF14030.6 KFP08264.1 - 2.3 8.2 3.3 5.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4245) Phage_holin_1 PF04531.13 KFP08264.1 - 3.4 8.3 4.6 6.6 7.3 0.0 2.5 3 0 0 3 3 3 0 Bacteriophage holin SCAMP PF04144.13 KFP08265.1 - 1.2e-69 234.1 16.1 1.5e-69 233.8 16.1 1.1 1 0 0 1 1 1 1 SCAMP family Lipase_GDSL_2 PF13472.6 KFP08266.1 - 0.00017 22.0 0.0 0.00037 20.9 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family NAPRTase_N PF17767.1 KFP08266.1 - 0.039 14.3 0.0 0.068 13.6 0.0 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DUF16 PF01519.16 KFP08266.1 - 0.15 12.5 0.1 0.33 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 TBCA PF02970.16 KFP08267.1 - 2.9e-23 82.0 8.0 3.1e-23 81.9 8.0 1.0 1 0 0 1 1 1 1 Tubulin binding cofactor A WD40 PF00400.32 KFP08268.1 - 2.5e-17 62.9 9.5 0.00051 20.8 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP08268.1 - 6.6e-05 23.1 0.8 3.3 8.1 0.0 4.1 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PDEase_I PF00233.19 KFP08269.1 - 3.7e-91 305.1 3.5 6e-91 304.4 3.5 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PAS_9 PF13426.7 KFP08269.1 - 4.2e-15 55.9 0.0 1.4e-14 54.2 0.0 2.0 1 1 0 1 1 1 1 PAS domain PAS PF00989.25 KFP08269.1 - 2e-13 50.3 0.0 5.9e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 KFP08269.1 - 7.9e-08 32.5 0.0 1.8e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KFP08269.1 - 9.7e-06 25.8 0.0 2.7e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 KFP08269.1 - 0.00016 21.6 0.0 0.00046 20.1 0.0 1.8 1 0 0 1 1 1 1 PAS domain CRF-BP PF05428.11 KFP08270.1 - 3e-177 587.9 0.1 3.4e-177 587.7 0.1 1.0 1 0 0 1 1 1 1 Corticotropin-releasing factor binding protein (CRF-BP) S_100 PF01023.19 KFP08271.1 - 1.8e-20 72.4 0.4 2.9e-20 71.7 0.4 1.4 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.32 KFP08271.1 - 2.2e-06 26.8 0.5 3.4e-05 23.1 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KFP08271.1 - 6.5e-06 26.5 0.6 9.4e-06 26.0 0.6 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP08271.1 - 0.00088 19.0 0.3 0.18 11.9 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFP08271.1 - 0.0035 16.8 1.4 0.043 13.3 0.2 2.4 2 0 0 2 2 2 1 EF hand DUF826 PF05696.11 KFP08271.1 - 0.053 13.6 0.2 0.084 13.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF826) RVT_1 PF00078.27 KFP08272.1 - 0.0055 16.3 0.0 0.0087 15.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RasGAP PF00616.19 KFP08273.1 - 3.1e-54 183.8 0.0 3.1e-54 183.8 0.0 2.5 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KFP08273.1 - 2.7e-38 131.2 14.1 2.7e-38 131.2 14.1 3.1 3 0 0 3 3 3 1 RasGAP C-terminus IQ PF00612.27 KFP08273.1 - 9.9e-20 68.4 10.4 6.2e-05 22.4 0.0 5.2 5 0 0 5 5 5 4 IQ calmodulin-binding motif CH PF00307.31 KFP08273.1 - 2.6e-16 59.8 0.0 2.3e-15 56.7 0.0 2.9 2 0 0 2 2 2 1 Calponin homology (CH) domain SHD1 PF03983.12 KFP08273.1 - 0.075 12.9 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 SLA1 homology domain 1, SHD1 PRR18 PF15671.5 KFP08273.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Proline-rich protein family 18 7tm_1 PF00001.21 KFP08274.1 - 2.1e-38 132.2 36.6 5e-37 127.7 36.2 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP08274.1 - 9.4e-05 22.2 28.4 9.4e-05 22.2 28.4 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx PRRSV_2b PF07069.11 KFP08274.1 - 0.0046 17.4 0.7 0.0046 17.4 0.7 3.8 4 1 1 5 5 5 1 Porcine reproductive and respiratory syndrome virus 2b DUF5345 PF17280.2 KFP08274.1 - 0.19 11.7 0.9 0.57 10.2 0.9 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5345) MFS_1 PF07690.16 KFP08275.1 - 3.9e-35 121.4 30.5 7.3e-25 87.6 14.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP08275.1 - 1.4e-32 113.1 17.7 2.9e-29 102.3 3.7 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Pentapeptide_4 PF13599.6 KFP08275.1 - 7.2e-07 29.3 9.1 1.2e-06 28.5 9.1 1.4 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) MFS_4 PF06779.14 KFP08275.1 - 0.0012 18.3 8.9 0.0012 18.3 8.9 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 KFP08275.1 - 0.0026 16.4 11.4 0.0026 16.4 11.4 2.6 2 0 0 2 2 2 1 MFS/sugar transport protein Pentapeptide_3 PF13576.6 KFP08275.1 - 0.01 15.9 7.6 0.085 13.0 7.6 2.3 1 1 1 2 2 2 0 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 KFP08275.1 - 0.036 13.7 0.9 0.083 12.6 0.4 1.7 1 1 1 2 2 2 0 Pentapeptide repeats (8 copies) MFS_3 PF05977.13 KFP08275.1 - 0.45 8.8 7.5 0.84 8.0 3.8 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector zf-C4H2 PF10146.9 KFP08277.1 - 0.0024 18.2 15.4 0.019 15.3 15.3 2.2 1 1 0 1 1 1 1 Zinc finger-containing protein CENP-F_leu_zip PF10473.9 KFP08277.1 - 0.027 14.5 14.8 0.25 11.3 8.2 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FliJ PF02050.16 KFP08277.1 - 0.15 12.3 15.3 0.87 9.8 0.2 2.6 2 1 0 2 2 2 0 Flagellar FliJ protein DUF3734 PF12536.8 KFP08277.1 - 0.17 12.2 6.4 0.95 9.8 1.0 2.7 1 1 1 2 2 2 0 Patatin phospholipase DUF5082 PF16888.5 KFP08277.1 - 0.35 11.2 11.6 1.2 9.4 2.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) FAM76 PF16046.5 KFP08277.1 - 0.56 9.5 11.1 0.087 12.2 6.6 1.8 1 1 1 2 2 2 0 FAM76 protein Cdh1_DBD_1 PF18196.1 KFP08277.1 - 0.68 10.3 7.9 0.2 12.0 2.9 2.6 3 0 0 3 3 3 0 Chromodomain helicase DNA-binding domain 1 DUF1192 PF06698.11 KFP08277.1 - 1.8 8.6 4.5 8.5 6.5 1.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) BRE1 PF08647.11 KFP08277.1 - 2.1 8.5 13.0 2.5 8.2 7.0 2.6 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase PKcGMP_CC PF16808.5 KFP08277.1 - 2.5 8.1 7.0 17 5.4 0.2 3.6 2 1 2 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Fib_alpha PF08702.10 KFP08277.1 - 5 7.3 12.0 6.6 6.9 2.8 2.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Ank_2 PF12796.7 KFP08278.1 - 1.9e-40 137.3 11.6 3.2e-18 66.1 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP08278.1 - 4.1e-32 109.8 4.1 8.9e-09 35.4 0.2 5.9 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP08278.1 - 7.2e-32 105.8 5.7 6.6e-05 23.0 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 KFP08278.1 - 1.2e-31 108.7 4.3 6e-10 39.5 0.3 4.8 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KFP08278.1 - 2.2e-27 94.2 9.8 4e-05 23.9 0.0 6.8 7 0 0 7 7 7 5 Ankyrin repeat Death PF00531.22 KFP08278.1 - 0.022 14.9 0.9 0.073 13.3 0.9 1.9 1 0 0 1 1 1 0 Death domain IMS PF00817.20 KFP08279.1 - 3.8e-43 147.1 0.0 1.4e-42 145.3 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 KFP08279.1 - 1.4e-16 61.2 0.5 5.9e-16 59.2 0.2 2.2 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KFP08279.1 - 6.4e-09 35.6 0.1 1.5e-08 34.5 0.1 1.7 1 0 0 1 1 1 1 IMS family HHH motif zf-C2H2_12 PF18658.1 KFP08279.1 - 0.00021 20.8 2.6 0.44 10.2 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger C2H2-type GhoS PF11080.8 KFP08279.1 - 0.0079 16.2 0.0 0.024 14.6 0.0 1.9 1 0 0 1 1 1 1 Endoribonuclease GhoS Cdd1 PF11731.8 KFP08279.1 - 0.022 15.0 0.0 0.09 13.0 0.0 2.0 1 0 0 1 1 1 0 Pathogenicity locus ATP-cone PF03477.16 KFP08279.1 - 0.03 14.9 1.8 4.5 7.9 0.5 2.6 2 0 0 2 2 2 0 ATP cone domain zf-Di19 PF05605.12 KFP08279.1 - 0.086 13.1 4.1 9.5 6.6 0.4 2.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-CHY PF05495.12 KFP08279.1 - 0.25 11.9 6.9 5.9 7.4 0.2 3.0 2 0 0 2 2 2 0 CHY zinc finger START PF01852.19 KFP08280.1 - 3.4e-30 105.0 1.2 5e-30 104.5 0.4 1.6 2 0 0 2 2 2 1 START domain PH PF00169.29 KFP08280.1 - 9.8e-13 48.5 0.8 2.7e-12 47.1 0.8 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFP08280.1 - 1.1e-08 35.3 0.1 3.5e-08 33.6 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFP08280.1 - 2.3e-05 24.8 3.2 0.0011 19.3 1.4 3.0 2 1 0 2 2 2 1 Pleckstrin homology domain Acyl_CoA_thio PF02551.15 KFP08280.1 - 0.02 14.8 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA thioesterase Med18 PF09637.10 KFP08281.1 - 1.3e-28 100.5 0.0 1.5e-28 100.3 0.0 1.0 1 0 0 1 1 1 1 Med18 protein HMG-CoA_red PF00368.18 KFP08282.1 - 1.3e-145 485.1 1.4 1.7e-145 484.7 1.4 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 KFP08282.1 - 7.7e-17 61.5 3.5 1.5e-16 60.6 3.5 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KFP08282.1 - 9.8e-09 33.9 1.6 1.5e-08 33.3 1.6 1.2 1 0 0 1 1 1 1 Patched family PapD_N PF00345.20 KFP08282.1 - 0.16 11.9 0.1 6.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Ank_4 PF13637.6 KFP08283.1 - 5.4e-14 52.4 1.8 6.3e-05 23.4 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP08283.1 - 1.9e-12 46.2 0.1 4.8e-06 26.5 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KFP08283.1 - 5.3e-12 46.2 0.1 5.4e-11 42.9 0.1 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP08283.1 - 3e-11 43.3 0.5 1.7e-06 28.2 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFP08283.1 - 3.8e-11 42.9 0.3 1.2e-06 28.7 0.3 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KFP08284.1 - 1.8e-18 66.7 0.2 3.5e-10 40.2 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP08284.1 - 3.4e-17 62.8 0.1 1.2e-10 41.8 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP08284.1 - 9.8e-17 60.8 0.5 5.2e-10 39.4 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFP08284.1 - 1.2e-14 54.0 1.5 0.00078 19.8 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat RAMA PF18755.1 KFP08284.1 - 7.2e-12 45.7 0.1 3.8e-11 43.4 0.0 2.2 2 0 0 2 2 2 1 Restriction Enzyme Adenine Methylase Associated Ank_3 PF13606.6 KFP08284.1 - 3.2e-11 42.4 0.1 0.0083 16.6 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Baculo_PEP_C PF04513.12 KFP08284.1 - 0.0092 16.0 9.3 0.62 10.1 1.1 2.5 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Sad1_UNC PF07738.13 KFP08285.1 - 5.8e-34 116.9 0.0 6.4e-34 116.8 0.0 1.0 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal zf-C2H2 PF00096.26 KFP08286.1 - 1.5e-16 59.8 22.9 0.00093 19.5 0.8 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP08286.1 - 2.8e-09 37.0 23.5 5.3e-05 23.5 0.8 5.1 5 0 0 5 5 5 3 Zinc-finger double domain FOXP-CC PF16159.5 KFP08286.1 - 3.1e-07 30.9 14.7 0.091 13.4 0.1 5.8 2 1 4 6 6 6 3 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KFP08286.1 - 4.2e-07 30.2 21.4 0.012 16.4 0.3 5.8 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFP08286.1 - 0.0048 17.2 9.1 0.059 13.7 1.2 4.4 2 1 1 4 4 4 1 C2H2-type zinc ribbon EpoR_lig-bind PF09067.10 KFP08286.1 - 0.11 12.7 0.2 0.25 11.6 0.2 1.5 1 0 0 1 1 1 0 Erythropoietin receptor, ligand binding zf-C2H2_aberr PF17017.5 KFP08286.1 - 0.21 11.7 8.1 27 4.9 0.1 4.3 1 1 3 4 4 4 0 Aberrant zinc-finger PcF PF09461.10 KFP08286.1 - 1.4 9.3 6.4 21 5.6 0.2 4.4 4 0 0 4 4 4 0 Phytotoxin PcF protein zf-C2H2_jaz PF12171.8 KFP08286.1 - 6.6 7.1 6.9 46 4.5 0.9 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP08286.1 - 6.8 7.2 6.7 12 6.5 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type RFX1_trans_act PF04589.13 KFP08287.1 - 2.9e-34 118.6 33.1 2.9e-34 118.6 33.1 3.0 2 1 0 2 2 2 1 RFX1 transcription activation region RFX_DNA_binding PF02257.15 KFP08287.1 - 1.2e-33 115.5 0.1 3.9e-33 113.9 0.1 1.9 1 0 0 1 1 1 1 RFX DNA-binding domain HisKA PF00512.25 KFP08287.1 - 0.017 15.1 0.3 0.043 13.8 0.3 1.7 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain Pox_D5 PF03288.16 KFP08287.1 - 0.07 13.6 0.0 0.2 12.1 0.0 1.8 1 0 0 1 1 1 0 Poxvirus D5 protein-like DUF2258 PF10015.9 KFP08287.1 - 0.16 12.1 0.2 0.66 10.1 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2258) CPL PF08144.11 KFP08288.1 - 2.6e-47 160.7 0.0 2.6e-47 160.7 0.0 3.4 3 1 2 5 5 5 1 CPL (NUC119) domain PUF PF00806.19 KFP08288.1 - 0.0058 16.3 2.1 4.4 7.2 0.1 4.5 5 0 0 5 5 5 2 Pumilio-family RNA binding repeat Arm-DNA-bind_2 PF12167.8 KFP08288.1 - 0.11 12.5 0.0 0.57 10.1 0.0 2.2 2 0 0 2 2 2 0 Arm DNA-binding domain Ldl_recept_a PF00057.18 KFP08289.1 - 3.6e-102 334.3 146.9 1.7e-14 53.7 13.9 8.6 8 0 0 8 8 8 8 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 KFP08289.1 - 2e-44 149.8 6.6 4.7e-10 39.8 0.0 5.4 5 0 0 5 5 5 5 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 KFP08289.1 - 2.2e-20 72.6 32.8 1.2e-10 41.4 5.2 6.3 6 2 0 6 6 6 3 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 KFP08289.1 - 5.3e-08 32.9 5.5 5.3e-08 32.9 5.5 11.0 6 3 0 6 6 6 2 Calcium-binding EGF domain cEGF PF12662.7 KFP08289.1 - 1.2e-05 25.2 28.9 0.019 14.9 0.9 6.7 5 1 0 5 5 5 3 Complement Clr-like EGF-like EGF PF00008.27 KFP08289.1 - 4.2e-05 23.8 15.7 0.00047 20.4 3.5 10.2 9 1 1 10 10 10 2 EGF-like domain SGL PF08450.12 KFP08289.1 - 0.0054 16.3 0.4 0.14 11.7 0.0 2.8 2 2 1 4 4 4 1 SMP-30/Gluconolactonase/LRE-like region hEGF PF12661.7 KFP08289.1 - 0.023 15.3 0.9 0.023 15.3 0.9 11.9 10 4 2 13 13 13 0 Human growth factor-like EGF Lipase_GDSL_2 PF13472.6 KFP08290.1 - 0.0025 18.2 0.0 0.0045 17.4 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 KFP08290.1 - 0.0066 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 OSK domain DUF4644 PF15486.6 KFP08290.1 - 0.022 14.6 0.1 0.04 13.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4644) Noelin-1 PF12308.8 KFP08290.1 - 0.14 12.1 0.8 0.27 11.3 0.8 1.4 1 0 0 1 1 1 0 Neurogenesis glycoprotein DUF4490 PF14892.6 KFP08291.1 - 0.0067 16.5 0.5 0.02 14.9 0.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) DUF410 PF04190.13 KFP08291.1 - 0.13 12.1 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF410) DMA PF03474.14 KFP08292.1 - 8.6e-17 60.4 0.1 1.3e-16 59.8 0.1 1.3 1 0 0 1 1 1 1 DMRTA motif Dmrt1 PF12374.8 KFP08293.1 - 6.4e-32 109.8 6.0 6.4e-32 109.8 6.0 2.2 2 0 0 2 2 2 1 Double-sex mab3 related transcription factor 1 Ustilago_mating PF05722.12 KFP08293.1 - 0.012 15.1 0.8 0.017 14.6 0.8 1.2 1 0 0 1 1 1 0 Ustilago B locus mating-type protein BDV_P40 PF06407.11 KFP08293.1 - 0.058 12.5 0.0 0.084 12.0 0.0 1.1 1 0 0 1 1 1 0 Borna disease virus P40 protein Ank_2 PF12796.7 KFP08294.1 - 3.8e-34 117.1 12.2 1.3e-17 64.2 0.5 3.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFP08294.1 - 1.8e-27 94.5 7.3 4.2e-07 30.1 0.1 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KFP08294.1 - 8.8e-27 92.8 10.7 6.5e-12 45.5 0.1 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP08294.1 - 1.3e-24 86.2 3.2 7.2e-12 45.6 0.0 5.0 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP08294.1 - 1.9e-24 83.0 5.2 4.2e-07 29.8 0.1 6.2 6 0 0 6 6 6 4 Ankyrin repeat DUF1694 PF07997.11 KFP08294.1 - 0.039 14.0 0.4 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1694) Tmemb_cc2 PF10267.9 KFP08294.1 - 0.091 11.9 5.1 0.036 13.2 2.1 1.6 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein KxDL PF10241.9 KFP08294.1 - 0.12 12.7 1.2 16 5.9 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein KN_motif PF12075.8 KFP08296.1 - 3.2e-19 68.4 0.1 7.3e-19 67.3 0.1 1.7 1 0 0 1 1 1 1 KN motif DHR-2 PF06920.13 KFP08297.1 - 4.7e-209 695.4 4.0 7.9e-209 694.7 4.0 1.3 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 KFP08297.1 - 4.3e-52 176.8 0.2 9.9e-52 175.6 0.2 1.7 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 KFP08297.1 - 1.5e-31 109.1 0.3 5.8e-31 107.2 0.3 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) DOCK_N PF16172.5 KFP08297.1 - 0.067 12.1 0.1 0.23 10.3 0.0 1.9 2 0 0 2 2 2 0 DOCK N-terminus GPR15L PF15854.5 KFP08297.1 - 0.16 12.3 0.1 0.58 10.4 0.1 2.0 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 cobW PF02492.19 KFP08298.1 - 1.3e-44 151.9 0.1 1.8e-44 151.5 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KFP08298.1 - 4.9e-19 68.1 0.0 8.6e-19 67.3 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 KFP08298.1 - 7.5e-06 25.6 0.3 0.00014 21.5 0.2 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFP08298.1 - 0.0027 17.7 0.1 1.5 8.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Phenyl_P_gamma PF09662.10 KFP08298.1 - 0.09 12.9 0.1 0.27 11.4 0.0 1.8 2 0 0 2 2 2 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) PGM_PMM_III PF02880.16 KFP08299.1 - 1.4e-27 96.1 0.0 2.5e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_I PF02878.16 KFP08299.1 - 2.9e-14 53.0 0.0 4.4e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KFP08299.1 - 1.3e-12 48.2 0.0 3.3e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II MAP1B_neuraxin PF00414.17 KFP08300.1 - 3.8e-09 35.7 100.1 0.038 13.5 3.9 13.9 13 0 0 13 13 13 12 Neuraxin and MAP1B repeat MRP-S27 PF10037.9 KFP08301.1 - 1.1e-106 357.0 12.6 2.8e-106 355.7 12.6 1.6 1 1 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 PPR_2 PF13041.6 KFP08301.1 - 0.0011 19.1 0.0 0.0039 17.4 0.0 2.0 1 0 0 1 1 1 1 PPR repeat family PPR_1 PF12854.7 KFP08301.1 - 0.0017 18.0 0.2 0.0074 16.0 0.1 2.0 2 0 0 2 2 2 1 PPR repeat PPR_3 PF13812.6 KFP08301.1 - 0.033 14.3 0.1 0.098 12.8 0.1 1.9 1 0 0 1 1 1 0 Pentatricopeptide repeat domain PPR PF01535.20 KFP08301.1 - 0.036 14.3 0.0 0.16 12.3 0.0 2.2 1 0 0 1 1 1 0 PPR repeat Perilipin PF03036.16 KFP08301.1 - 2 7.4 14.2 8.8 5.2 14.2 1.9 1 1 0 1 1 1 0 Perilipin family MRP-S27 PF10037.9 KFP08302.1 - 2.5e-07 29.9 5.9 1.6e-06 27.3 5.9 1.9 1 1 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 PPR_2 PF13041.6 KFP08302.1 - 3e-05 24.1 0.1 0.00011 22.3 0.1 2.0 1 0 0 1 1 1 1 PPR repeat family PPR PF01535.20 KFP08302.1 - 0.00025 21.1 0.3 0.0091 16.2 0.1 3.0 2 0 0 2 2 2 1 PPR repeat DED PF01335.21 KFP08302.1 - 0.013 15.8 6.2 4.7 7.6 0.2 4.0 4 0 0 4 4 4 0 Death effector domain PPR_3 PF13812.6 KFP08302.1 - 0.071 13.2 2.7 2.4 8.3 0.0 2.9 3 0 0 3 3 3 0 Pentatricopeptide repeat domain HEAT_EZ PF13513.6 KFP08303.1 - 1.4e-35 121.2 0.5 1.5e-12 47.7 0.0 10.9 8 2 4 12 12 12 4 HEAT-like repeat HEAT PF02985.22 KFP08303.1 - 3e-32 107.9 8.4 0.0031 17.7 0.0 11.7 11 0 0 11 11 11 7 HEAT repeat HEAT_2 PF13646.6 KFP08303.1 - 6.6e-21 74.5 0.0 7e-06 26.3 0.0 6.5 5 2 2 7 7 7 5 HEAT repeats Cnd1 PF12717.7 KFP08303.1 - 2e-16 60.4 0.4 0.00043 20.3 0.3 4.5 3 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 KFP08303.1 - 2.4e-16 59.1 3.9 0.0073 16.3 0.0 7.8 8 0 0 8 8 7 3 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 KFP08303.1 - 1.3e-15 57.0 0.1 8.1e-15 54.5 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 KFP08303.1 - 4.7e-15 56.0 0.7 0.0011 19.5 0.2 6.9 5 2 3 8 8 8 5 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KFP08303.1 - 5.7e-11 41.7 4.0 0.0017 17.0 0.4 5.1 2 2 1 4 4 4 4 Adaptin N terminal region UNC45-central PF11701.8 KFP08303.1 - 4.6e-05 23.4 2.7 0.0089 16.0 0.1 3.9 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central Dopey_N PF04118.14 KFP08303.1 - 0.00027 20.1 0.5 0.0015 17.7 0.0 2.3 2 1 0 2 2 2 1 Dopey, N-terminal CLASP_N PF12348.8 KFP08303.1 - 0.00077 19.1 0.8 1.1 8.8 0.0 4.4 3 2 1 4 4 4 1 CLASP N terminal RTP1_C1 PF10363.9 KFP08303.1 - 0.00093 19.4 0.2 0.075 13.2 0.1 3.8 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Xpo1 PF08389.12 KFP08303.1 - 0.0021 18.1 1.2 4.3 7.4 0.2 4.8 4 1 0 4 4 3 1 Exportin 1-like protein MMS19_C PF12460.8 KFP08303.1 - 0.0072 15.5 5.0 0.71 8.9 0.1 4.4 3 2 1 4 4 4 2 RNAPII transcription regulator C-terminal DUF3437 PF11919.8 KFP08303.1 - 0.0077 16.1 0.6 3.6 7.6 0.0 4.7 5 0 0 5 5 5 1 Domain of unknown function (DUF3437) DUF3689 PF12463.8 KFP08303.1 - 0.023 14.0 0.0 0.13 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3689) Tti2 PF10521.9 KFP08303.1 - 0.09 12.3 1.1 42 3.5 0.0 4.6 3 3 2 5 5 5 0 Tti2 family TAF6_C PF07571.13 KFP08303.1 - 0.14 12.5 0.0 4 7.8 0.0 3.2 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain TAFH PF07531.14 KFP08303.1 - 0.3 11.2 3.5 12 6.1 0.0 4.2 5 1 1 6 6 4 0 NHR1 homology to TAF DUF2457 PF10446.9 KFP08303.1 - 2.3 7.3 7.1 3.3 6.8 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pkinase PF00069.25 KFP08304.1 - 1e-75 254.6 0.0 1.4e-75 254.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP08304.1 - 1.1e-36 126.5 0.0 1.3e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KFP08304.1 - 3.5e-05 23.5 0.1 6e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KFP08304.1 - 0.00026 20.4 0.1 0.00056 19.3 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KFP08304.1 - 0.024 14.3 0.1 7.1 6.2 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Glycos_trans_3N PF02885.17 KFP08304.1 - 0.076 12.9 0.4 0.47 10.3 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain RabGAP-TBC PF00566.18 KFP08305.1 - 2.7e-57 193.9 3.6 2.7e-57 193.9 3.6 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PH PF00169.29 KFP08305.1 - 9e-05 22.9 0.0 0.00029 21.3 0.0 1.9 1 0 0 1 1 1 1 PH domain KRAB PF01352.27 KFP08305.1 - 0.0037 16.9 0.3 0.02 14.6 0.1 2.3 2 0 0 2 2 2 1 KRAB box HIP1_clath_bdg PF16515.5 KFP08305.1 - 0.0082 16.7 2.3 0.0082 16.7 2.3 4.6 2 1 1 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 KFP08305.1 - 0.8 9.8 12.4 1.9 8.5 0.8 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KFP08305.1 - 3.2 6.5 25.1 1.5 7.6 13.0 2.8 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF4407 PF14362.6 KFP08305.1 - 4.5 6.5 12.5 1.3 8.3 7.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DivIC PF04977.15 KFP08305.1 - 6.4 6.6 26.3 0.35 10.7 5.3 4.1 3 1 0 3 3 3 0 Septum formation initiator EF-hand_7 PF13499.6 KFP08306.1 - 2.2e-12 47.3 2.4 1.1e-09 38.6 0.8 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFP08306.1 - 9e-09 34.3 7.9 9.9e-05 21.6 0.5 3.6 3 1 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFP08306.1 - 1.3e-08 34.0 4.1 0.0039 17.0 0.3 3.7 3 1 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 KFP08306.1 - 0.00058 19.7 6.9 0.013 15.3 1.7 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP08306.1 - 0.0016 17.8 8.1 0.045 13.3 0.8 3.7 3 1 1 4 4 4 2 EF hand PMBR PF09373.10 KFP08306.1 - 0.016 15.4 0.0 7.1 7.0 0.0 3.5 4 0 0 4 4 4 0 Pseudomurein-binding repeat Dockerin_1 PF00404.18 KFP08306.1 - 0.063 13.5 0.0 0.16 12.2 0.0 1.7 1 1 0 1 1 1 0 Dockerin type I domain Iso_dh PF00180.20 KFP08307.1 - 2e-112 375.8 0.0 2.2e-112 375.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase AMP-binding PF00501.28 KFP08308.1 - 3e-88 296.3 0.0 3.5e-88 296.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DnaJ_C PF01556.18 KFP08309.1 - 1.4e-44 151.7 1.1 1.9e-44 151.3 1.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFP08309.1 - 2.9e-25 88.1 2.4 4.7e-25 87.5 2.4 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KFP08309.1 - 8.5e-15 54.9 20.2 1.4e-14 54.1 20.2 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KFP08309.1 - 0.1 12.6 7.9 1.7 8.7 0.2 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 KFP08309.1 - 0.24 11.1 7.3 1.1 8.9 2.6 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zf-RING_10 PF16685.5 KFP08309.1 - 0.72 10.0 11.7 0.072 13.2 2.2 2.4 1 1 1 2 2 2 0 zinc RING finger of MSL2 zf_CopZ PF18423.1 KFP08309.1 - 0.87 9.6 5.1 14 5.7 0.5 2.6 2 0 0 2 2 2 0 Zinc binding domain Anti-TRAP PF15777.5 KFP08309.1 - 1.2 9.1 19.1 1.9 8.5 5.3 2.7 1 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein RseC_MucC PF04246.12 KFP08309.1 - 1.9 8.5 6.2 0.12 12.4 0.8 1.8 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC PADR1 PF08063.12 KFP08309.1 - 1.9 8.3 9.2 1.2 9.0 0.2 3.3 3 0 0 3 3 3 0 PADR1 (NUC008) domain DUF2614 PF11023.8 KFP08309.1 - 7.1 6.8 6.6 3.4 7.8 0.7 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain WD40 PF00400.32 KFP08310.1 - 2.3e-40 135.8 19.3 1.5e-09 38.3 0.0 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP08310.1 - 4.5e-24 84.6 0.1 1.1e-07 32.0 0.0 5.9 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP08310.1 - 8.1e-09 34.9 4.7 0.017 14.1 0.0 4.9 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFP08310.1 - 2.4e-08 34.1 0.0 3.3e-05 23.9 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KFP08310.1 - 6.5e-07 28.2 1.2 0.69 8.4 0.0 3.7 1 1 3 4 4 4 4 Cytochrome D1 heme domain Nup160 PF11715.8 KFP08310.1 - 4.8e-05 22.2 0.2 0.053 12.2 0.0 2.6 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PD40 PF07676.12 KFP08310.1 - 6.9e-05 22.7 0.1 1.1 9.2 0.0 3.4 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Frtz PF11768.8 KFP08310.1 - 0.003 16.0 0.0 0.012 13.9 0.0 1.8 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KFP08310.1 - 0.0031 16.9 0.7 0.36 10.1 0.0 3.1 3 1 1 4 4 4 1 WD40-like domain GSDH PF07995.11 KFP08310.1 - 0.006 15.9 0.0 0.62 9.3 0.0 2.3 1 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase DUF2415 PF10313.9 KFP08310.1 - 0.018 15.0 0.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) PALB2_WD40 PF16756.5 KFP08310.1 - 0.019 13.9 0.2 1.8 7.4 0.1 2.8 2 1 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain PQQ PF01011.21 KFP08310.1 - 0.022 14.7 2.8 8.9 6.4 0.0 4.1 4 0 0 4 4 4 0 PQQ enzyme repeat DUF5046 PF16465.5 KFP08310.1 - 0.032 13.7 0.0 0.2 11.1 0.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5046) NYD-SP28 PF14772.6 KFP08311.1 - 1.1e-25 89.6 21.1 1.1e-25 89.6 21.1 6.1 4 1 3 7 7 7 1 Sperm tail NYD-SP28_assoc PF14775.6 KFP08311.1 - 4.3e-22 78.0 2.6 4.3e-22 78.0 2.6 5.3 4 2 2 6 6 6 1 Sperm tail C-terminal domain DUF3584 PF12128.8 KFP08311.1 - 0.65 7.4 59.8 1 6.8 59.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Stathmin PF00836.19 KFP08313.1 - 9.6e-59 197.2 20.2 1.2e-58 196.9 20.2 1.1 1 0 0 1 1 1 1 Stathmin family Pex19 PF04614.12 KFP08313.1 - 0.0039 17.0 6.7 0.0047 16.7 6.7 1.1 1 0 0 1 1 1 1 Pex19 protein family Exonuc_VII_L PF02601.15 KFP08313.1 - 0.56 9.7 8.0 0.6 9.6 8.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 KFP08313.1 - 0.68 9.0 15.4 0.89 8.6 15.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CCDC84 PF14968.6 KFP08313.1 - 1.2 8.7 11.2 7.3 6.1 7.6 2.1 2 0 0 2 2 2 0 Coiled coil protein 84 Ribonuc_2-5A PF06479.12 KFP08313.1 - 2.7 8.2 9.9 11 6.3 9.9 1.9 1 1 0 1 1 1 0 Ribonuclease 2-5A EF-hand_14 PF17959.1 KFP08313.1 - 7.1 7.0 8.5 1.6 9.1 2.7 2.2 1 1 1 2 2 2 0 EF-hand domain Fibrinogen_C PF00147.18 KFP08314.1 - 3.5e-44 151.2 0.4 4e-44 151.1 0.4 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Yae1_N PF09811.9 KFP08315.1 - 6.6e-14 51.3 61.6 0.0044 16.7 7.2 7.5 4 2 1 6 6 6 4 Essential protein Yae1, N terminal NPP PF08384.10 KFP08317.1 - 1.7e-22 79.1 1.6 2.7e-22 78.5 1.6 1.3 1 0 0 1 1 1 1 Pro-opiomelanocortin, N-terminal region ACTH_domain PF00976.18 KFP08317.1 - 1.3e-15 56.9 29.9 8.2e-08 32.0 6.3 3.9 3 0 0 3 3 3 3 Corticotropin ACTH domain Op_neuropeptide PF08035.11 KFP08317.1 - 1.4e-13 50.4 0.0 2.3e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Opioids neuropeptide CAP_N PF01213.19 KFP08317.1 - 0.0014 18.1 0.9 0.0019 17.8 0.2 1.5 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal TLV_coat PF00429.19 KFP08318.1 - 2.6e-109 366.4 0.5 2.9e-109 366.3 0.5 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) SlyX PF04102.12 KFP08318.1 - 0.0033 18.0 0.3 0.016 15.8 0.0 2.2 1 1 1 2 2 2 1 SlyX Ras PF00071.22 KFP08320.1 - 5.7e-36 123.6 0.0 7.5e-36 123.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP08320.1 - 1.6e-18 67.0 0.0 5.8e-18 65.2 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP08320.1 - 2.6e-12 46.5 0.0 3.4e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DnaJ PF00226.31 KFP08320.1 - 5.1e-12 45.7 0.0 9e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain GTP_EFTU PF00009.27 KFP08320.1 - 0.00059 19.4 0.0 0.0013 18.3 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain CENP-O PF09496.10 KFP08321.1 - 4e-11 43.3 3.6 4.8e-11 43.0 0.1 2.2 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component BAR_2 PF10455.9 KFP08321.1 - 0.0009 18.5 0.1 0.00098 18.3 0.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking FapA PF03961.13 KFP08321.1 - 0.13 10.8 1.4 0.2 10.2 1.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Csm1_N PF18504.1 KFP08321.1 - 0.41 11.0 11.1 1 9.8 11.1 1.6 1 0 0 1 1 1 0 Csm1 N-terminal domain AKNA PF12443.8 KFP08321.1 - 0.45 11.2 9.3 1 10.0 5.3 2.9 2 1 1 3 3 3 0 AT-hook-containing transcription factor Phage_GPO PF05929.11 KFP08321.1 - 0.49 10.0 3.4 0.81 9.3 3.4 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase PAS_11 PF14598.6 KFP08322.1 - 5.9e-37 126.3 0.0 7e-33 113.1 0.0 2.4 2 0 0 2 2 2 2 PAS domain NCOA_u2 PF16665.5 KFP08322.1 - 2.9e-31 108.3 16.1 2.9e-31 108.3 16.1 5.9 7 1 0 7 7 7 1 Unstructured region on nuclear receptor coactivator protein DUF1518 PF07469.12 KFP08322.1 - 4.5e-30 103.8 42.5 6e-19 68.2 20.8 7.5 6 1 1 7 7 7 2 Domain of unknown function (DUF1518) SRC-1 PF08832.10 KFP08322.1 - 1.9e-22 80.1 2.7 1.5e-21 77.2 2.7 2.7 1 0 0 1 1 1 1 Steroid receptor coactivator Nuc_rec_co-act PF08815.10 KFP08322.1 - 6.9e-21 73.8 2.1 6.9e-21 73.8 2.1 2.3 3 0 0 3 3 3 1 Nuclear receptor coactivator PAS PF00989.25 KFP08322.1 - 4e-09 36.5 0.0 3.4e-08 33.5 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 KFP08322.1 - 2e-07 31.2 0.0 0.00054 20.2 0.0 2.4 2 0 0 2 2 2 2 PAS fold DUF4927 PF16279.5 KFP08322.1 - 9.1e-07 29.8 7.2 7.8e-06 26.8 5.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4927) PAS_9 PF13426.7 KFP08322.1 - 1.7e-06 28.2 0.0 2.2e-05 24.6 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 KFP08322.1 - 0.017 15.4 0.0 0.05 13.9 0.0 1.8 1 0 0 1 1 1 0 PAS fold FOXP-CC PF16159.5 KFP08323.1 - 0.0017 18.9 0.1 0.005 17.4 0.0 1.8 2 0 0 2 2 2 1 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KFP08323.1 - 0.32 12.0 0.2 0.32 12.0 0.2 2.4 3 0 0 3 3 3 0 C2H2-type zinc finger Opiods_neuropep PF01160.18 KFP08324.1 - 5.4e-14 52.0 2.8 8.1e-14 51.4 2.8 1.3 1 0 0 1 1 1 1 Vertebrate endogenous opioids neuropeptide DUF4192 PF13830.6 KFP08324.1 - 0.0062 16.6 1.2 0.0073 16.4 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4192) DUF1272 PF06906.11 KFP08324.1 - 0.14 12.3 2.5 0.25 11.5 2.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) Hus1 PF04005.12 KFP08324.1 - 0.28 10.2 0.0 0.39 9.8 0.0 1.1 1 0 0 1 1 1 0 Hus1-like protein Pkinase PF00069.25 KFP08325.1 - 1e-48 166.0 0.0 4.1e-48 164.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP08325.1 - 3.1e-35 121.7 0.1 6.1e-26 91.3 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KFP08325.1 - 0.00028 20.3 0.0 0.00052 19.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP08325.1 - 0.00046 20.2 0.1 0.0094 15.9 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family ABC1 PF03109.16 KFP08325.1 - 0.014 15.5 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 ABC1 family RIO1 PF01163.22 KFP08325.1 - 0.017 14.7 0.0 0.045 13.3 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 KFP08325.1 - 0.082 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KFP08325.1 - 0.12 11.7 0.0 0.54 9.5 0.0 2.0 2 1 0 2 2 2 0 Kinase-like Radical_SAM_C PF16199.5 KFP08327.1 - 1.3e-34 118.1 0.0 2.8e-34 117.0 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KFP08327.1 - 1.3e-21 77.7 2.3 8.6e-21 75.0 0.1 3.1 4 0 0 4 4 4 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KFP08327.1 - 6e-10 39.4 0.1 1.1e-09 38.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFP08327.1 - 5.2e-05 23.2 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFP08327.1 - 0.15 12.1 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein F-box-like PF12937.7 KFP08328.1 - 4.7e-09 36.0 5.6 8.6e-09 35.2 5.6 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFP08328.1 - 2.9e-08 33.4 2.6 6.3e-08 32.3 2.6 1.5 1 0 0 1 1 1 1 F-box domain HLH PF00010.26 KFP08329.1 - 7e-16 57.9 2.4 1.1e-15 57.3 2.4 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 KFP08329.1 - 4e-07 30.1 0.8 8.3e-07 29.1 0.8 1.6 1 0 0 1 1 1 1 Hairy Orange HLH PF00010.26 KFP08330.1 - 3.8e-15 55.6 2.1 6.5e-15 54.8 2.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 KFP08330.1 - 0.00022 21.4 0.2 0.00037 20.6 0.2 1.4 1 0 0 1 1 1 1 Hairy Orange HLH PF00010.26 KFP08331.1 - 7.8e-16 57.8 3.4 1.3e-15 57.1 3.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 KFP08331.1 - 3.5e-09 36.7 0.4 5.2e-09 36.2 0.4 1.3 1 0 0 1 1 1 1 Hairy Orange Fumble PF03630.14 KFP08332.1 - 1.8e-129 431.7 3.3 2.3e-129 431.3 3.3 1.1 1 0 0 1 1 1 1 Fumble DUF89 PF01937.19 KFP08332.1 - 2.2e-56 191.4 0.0 3.4e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 vATP-synt_E PF01991.18 KFP08332.1 - 0.042 13.2 0.0 0.11 11.8 0.0 1.7 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Lig_chan PF00060.26 KFP08333.1 - 3.3e-40 137.4 0.2 5.3e-40 136.7 0.2 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFP08333.1 - 9.4e-37 125.7 0.0 1.7e-36 124.9 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFP08333.1 - 2.7e-20 72.8 0.0 3.9e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Borrelia_orfA PF02414.15 KFP08333.1 - 0.0031 17.2 0.2 0.0045 16.7 0.2 1.1 1 0 0 1 1 1 1 Borrelia ORF-A Ion_trans_2 PF07885.16 KFP08333.1 - 0.095 12.7 1.1 0.76 9.8 1.3 2.6 2 1 0 2 2 2 0 Ion channel PI-PLC-X PF00388.19 KFP08334.1 - 4.3e-65 217.7 0.1 8.8e-65 216.7 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFP08334.1 - 8.5e-41 138.9 0.5 3.2e-40 137.1 0.5 2.1 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 KFP08334.1 - 2.4e-18 66.4 0.1 8e-18 64.7 0.1 2.0 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 KFP08334.1 - 5.2e-16 58.8 0.0 1.3e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.6 KFP08334.1 - 1.8e-13 50.7 3.7 4e-12 46.4 0.5 2.8 2 0 0 2 2 2 1 EF-hand domain pair PH_12 PF16457.5 KFP08334.1 - 3e-09 37.5 0.0 3e-09 37.5 0.0 2.7 3 0 0 3 3 1 1 Pleckstrin homology domain EF-hand_1 PF00036.32 KFP08334.1 - 1.8e-08 33.3 5.5 0.0004 19.7 0.0 3.2 3 1 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFP08334.1 - 1.3e-07 30.9 4.6 0.0086 15.9 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_10 PF14788.6 KFP08334.1 - 2e-06 27.6 1.5 1.1e-05 25.2 0.3 2.5 1 1 1 2 2 2 1 EF hand EF-hand_8 PF13833.6 KFP08334.1 - 7.4e-06 25.7 5.0 0.0026 17.6 0.7 3.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP08334.1 - 7.7e-05 22.0 1.9 0.0008 18.8 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.7 KFP08334.1 - 0.001 19.0 0.5 0.0042 17.0 0.1 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand PH PF00169.29 KFP08334.1 - 0.007 16.9 0.0 0.021 15.3 0.0 1.8 1 0 0 1 1 1 1 PH domain SPARC_Ca_bdg PF10591.9 KFP08334.1 - 0.097 13.0 0.1 0.29 11.5 0.1 1.8 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KFP08334.1 - 0.12 12.7 0.1 0.41 11.0 0.1 2.0 1 0 0 1 1 1 0 EF-hand domain Pex2_Pex12 PF04757.14 KFP08335.1 - 2.3e-35 122.2 3.2 2.9e-35 121.9 3.2 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 KFP08335.1 - 3.2e-09 37.0 14.8 6e-09 36.1 14.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFP08335.1 - 6.9e-09 35.4 11.8 1.3e-08 34.6 11.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP08335.1 - 4.8e-08 32.7 10.7 8.4e-08 32.0 10.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFP08335.1 - 9.9e-07 28.5 12.6 2e-06 27.6 12.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP08335.1 - 2.4e-06 27.3 12.8 4.4e-06 26.4 12.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP08335.1 - 2.9e-05 23.9 11.2 5.5e-05 23.0 11.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFP08335.1 - 3e-05 24.2 10.9 6.8e-05 23.1 10.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFP08335.1 - 3.8e-05 23.6 12.1 7.3e-05 22.7 6.1 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFP08335.1 - 0.0089 16.2 10.5 0.028 14.6 10.6 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF3290 PF11694.8 KFP08335.1 - 0.025 14.5 0.1 0.047 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) zf-RING_6 PF14835.6 KFP08335.1 - 0.067 13.1 4.1 0.14 12.0 4.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 KFP08335.1 - 0.08 12.7 4.2 1 9.2 3.0 2.6 2 1 0 2 2 2 0 RING-like zinc finger zf-ANAPC11 PF12861.7 KFP08335.1 - 0.11 12.6 5.4 0.19 11.8 5.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KFP08335.1 - 0.18 11.6 10.1 0.35 10.7 10.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Rer1 PF03248.13 KFP08336.1 - 7.2e-78 260.2 8.2 8.2e-78 260.0 8.2 1.0 1 0 0 1 1 1 1 Rer1 family Bestrophin PF01062.21 KFP08336.1 - 0.025 14.0 0.9 0.051 13.0 0.9 1.4 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel DUF2208 PF09973.9 KFP08336.1 - 0.11 12.1 0.3 0.11 12.1 0.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Ski_Sno PF02437.17 KFP08337.1 - 1e-45 153.9 0.4 2.1e-45 152.9 0.4 1.5 1 0 0 1 1 1 1 SKI/SNO/DAC family c-SKI_SMAD_bind PF08782.10 KFP08337.1 - 2.6e-40 136.6 1.1 7.7e-40 135.0 1.1 1.9 1 0 0 1 1 1 1 c-SKI Smad4 binding domain Ku_C PF03730.14 KFP08337.1 - 0.073 13.8 0.5 0.073 13.8 0.5 3.6 3 0 0 3 3 3 0 Ku70/Ku80 C-terminal arm AKAP7_NLS PF10469.9 KFP08337.1 - 0.54 10.1 3.8 0.5 10.2 2.1 1.8 2 0 0 2 2 2 0 AKAP7 2'5' RNA ligase-like domain AAA_13 PF13166.6 KFP08337.1 - 5.4 5.5 20.0 0.57 8.8 15.7 1.5 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 KFP08338.1 - 4.4e-64 216.4 0.0 5.8e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP08338.1 - 2.6e-33 115.4 0.0 4.3e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.24 KFP08338.1 - 7.5e-15 54.6 0.1 1.8e-14 53.4 0.1 1.7 1 0 0 1 1 1 1 PB1 domain C1_1 PF00130.22 KFP08338.1 - 1.1e-14 54.0 6.7 2.5e-14 52.9 6.7 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KFP08338.1 - 1e-05 26.1 1.6 2.5e-05 24.9 1.6 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFP08338.1 - 3.6e-05 23.2 0.0 6.7e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFP08338.1 - 0.021 13.8 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KFP08338.1 - 0.025 14.0 0.0 0.061 12.7 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family C1_2 PF03107.16 KFP08338.1 - 0.034 14.5 2.5 0.079 13.3 2.5 1.6 1 0 0 1 1 1 0 C1 domain FTA2 PF13095.6 KFP08338.1 - 0.04 13.5 0.1 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFP08338.1 - 0.052 13.5 0.1 0.24 11.3 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DZR PF12773.7 KFP08338.1 - 0.41 10.7 2.2 1.2 9.3 2.2 1.8 1 0 0 1 1 1 0 Double zinc ribbon Neur_chan_LBD PF02931.23 KFP08339.1 - 1.5e-48 165.1 0.1 2.4e-48 164.5 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP08339.1 - 2e-35 123.0 1.4 1.7e-30 106.9 1.6 2.3 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region PapD-like PF14874.6 KFP08340.1 - 7.1e-07 29.3 0.0 0.022 14.9 0.0 2.8 3 0 0 3 3 3 2 Flagellar-associated PapD-like ASH PF15780.5 KFP08340.1 - 1.8e-05 24.8 0.0 1.6 8.9 0.0 3.4 3 0 0 3 3 3 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 KFP08340.1 - 0.003 17.8 0.0 7.3 6.9 0.0 3.2 3 0 0 3 3 3 1 Transmembrane protein 131-like TMEM52 PF14979.6 KFP08341.1 - 5.4e-25 88.1 2.0 5.8e-25 88.0 2.0 1.0 1 0 0 1 1 1 1 Transmembrane 52 DUF2897 PF11446.8 KFP08341.1 - 1.9 8.5 3.3 2.5 8.1 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) NAD_kinase PF01513.21 KFP08342.1 - 3.2e-66 223.5 0.1 3.9e-66 223.2 0.1 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KFP08342.1 - 0.046 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Guanylate_cyc PF00211.20 KFP08343.1 - 0.081 12.5 0.2 0.33 10.5 0.1 1.9 1 1 1 2 2 2 0 Adenylate and Guanylate cyclase catalytic domain TPT PF03151.16 KFP08344.1 - 1.2e-91 307.1 23.6 1.4e-91 306.9 23.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFP08344.1 - 8.3e-12 45.4 29.1 6.5e-06 26.4 12.5 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KFP08344.1 - 1e-07 31.5 24.7 1.4e-07 31.0 24.7 1.1 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KFP08344.1 - 0.0057 15.9 8.6 0.0057 15.9 8.6 1.7 1 1 0 1 1 1 1 Nucleotide-sugar transporter Pkinase PF00069.25 KFP08345.1 - 7.3e-66 222.2 0.9 1.2e-65 221.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP08345.1 - 2.6e-30 105.6 0.2 9.1e-30 103.8 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP08345.1 - 7e-06 25.6 0.3 0.00089 18.7 0.0 2.5 1 1 0 2 2 2 2 Kinase-like Peptidase_M10 PF00413.24 KFP08346.1 - 3.1e-38 131.1 0.1 4.2e-38 130.7 0.1 1.2 1 0 0 1 1 1 1 Matrixin ShK PF01549.24 KFP08346.1 - 5e-09 36.5 7.2 8.3e-09 35.8 7.2 1.4 1 0 0 1 1 1 1 ShK domain-like Ig_2 PF13895.6 KFP08346.1 - 2.2e-05 24.7 0.1 3.7e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFP08346.1 - 6.3e-05 23.5 0.1 0.00012 22.6 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain DUF4953 PF16313.5 KFP08346.1 - 0.00038 19.8 0.4 0.00054 19.3 0.4 1.1 1 0 0 1 1 1 1 Met-zincin Reprolysin_4 PF13583.6 KFP08346.1 - 0.0036 17.0 0.1 0.0056 16.4 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like V-set PF07686.17 KFP08346.1 - 0.013 15.7 0.2 0.32 11.2 0.0 2.3 1 1 1 2 2 2 0 Immunoglobulin V-set domain Reprolysin_3 PF13582.6 KFP08346.1 - 0.017 15.6 0.9 0.029 14.9 0.9 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like I-set PF07679.16 KFP08346.1 - 0.02 15.0 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain Reprolysin_5 PF13688.6 KFP08346.1 - 0.025 14.7 1.4 0.17 12.1 1.6 1.8 1 1 1 2 2 2 0 Metallo-peptidase family M12 Bud13 PF09736.9 KFP08346.1 - 0.04 14.3 0.0 0.085 13.3 0.0 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Peptidase_M57 PF12388.8 KFP08346.1 - 0.07 12.7 0.2 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Astacin PF01400.24 KFP08346.1 - 0.21 11.2 3.9 0.58 9.7 2.0 2.6 3 1 1 4 4 4 0 Astacin (Peptidase family M12A) ATG16 PF08614.11 KFP08347.1 - 4.1 7.6 35.2 0.59 10.3 20.3 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) JIP_LZII PF16471.5 KFP08347.1 - 6 7.1 20.2 0.096 12.9 2.9 3.8 2 2 0 3 3 3 0 JNK-interacting protein leucine zipper II DUF4407 PF14362.6 KFP08347.1 - 9.2 5.5 20.1 3.7 6.8 17.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Ssu72 PF04722.13 KFP08349.1 - 1.1e-77 260.0 0.1 1.2e-77 259.8 0.1 1.0 1 0 0 1 1 1 1 Ssu72-like protein TMEM240 PF15207.6 KFP08350.1 - 1.4e-75 252.8 1.5 1.7e-75 252.6 1.5 1.0 1 0 0 1 1 1 1 TMEM240 family DUF3523 PF12037.8 KFP08351.1 - 3.7e-88 295.3 31.9 6.5e-88 294.6 31.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 KFP08351.1 - 2.2e-21 76.7 0.0 6.9e-21 75.0 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KFP08351.1 - 0.00017 21.1 0.2 0.0045 16.4 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KFP08351.1 - 0.00024 21.5 8.5 0.0044 17.4 0.0 3.7 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KFP08351.1 - 0.00057 19.7 0.0 0.0017 18.1 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 KFP08351.1 - 0.001 18.8 0.0 0.0037 17.0 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain Zot PF05707.12 KFP08351.1 - 0.0012 18.6 0.5 0.054 13.1 0.1 3.0 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_24 PF13479.6 KFP08351.1 - 0.0017 18.1 0.0 0.0042 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFP08351.1 - 0.0035 17.5 0.0 0.0035 17.5 0.0 2.9 2 1 0 2 2 1 1 AAA domain ATPase PF06745.13 KFP08351.1 - 0.0061 15.9 0.0 0.0061 15.9 0.0 2.2 2 1 0 2 2 1 1 KaiC AAA_22 PF13401.6 KFP08351.1 - 0.0083 16.4 9.2 0.35 11.1 0.0 3.6 3 1 0 3 3 2 2 AAA domain AAA_5 PF07728.14 KFP08351.1 - 0.0093 16.0 4.6 0.046 13.7 0.0 3.5 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.6 KFP08351.1 - 0.013 15.6 0.3 0.037 14.1 0.0 1.9 2 0 0 2 2 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KFP08351.1 - 0.036 14.4 0.0 0.084 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 KFP08351.1 - 0.047 13.7 0.0 0.2 11.7 0.0 2.0 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KFP08351.1 - 0.055 13.4 0.1 0.42 10.5 0.0 2.5 3 0 0 3 3 3 0 NACHT domain AAA_7 PF12775.7 KFP08351.1 - 0.1 12.1 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KFP08351.1 - 0.18 12.4 2.4 0.25 11.9 0.0 2.5 2 1 0 2 2 1 0 AAA domain AAA_28 PF13521.6 KFP08351.1 - 0.56 10.4 0.0 0.56 10.4 0.0 3.2 2 2 1 3 3 3 0 AAA domain AAA_11 PF13086.6 KFP08351.1 - 0.73 9.6 0.0 0.73 9.6 0.0 2.8 2 1 0 2 2 1 0 AAA domain Borrelia_P83 PF05262.11 KFP08351.1 - 1.4 7.3 19.8 2.4 6.6 19.8 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein TFIIA PF03153.13 KFP08351.1 - 3.1 7.7 19.5 5.2 6.9 19.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_25 PF13481.6 KFP08351.1 - 4.1 6.9 7.1 0.25 10.9 0.2 2.5 2 1 0 2 2 2 0 AAA domain BORG_CEP PF14957.6 KFP08351.1 - 5.3 8.2 7.1 14 6.9 7.1 1.7 1 0 0 1 1 1 0 Cdc42 effector VWA PF00092.28 KFP08352.1 - 1e-35 123.6 0.0 1.7e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain fn3 PF00041.21 KFP08352.1 - 3.2e-20 72.3 1.4 1.8e-09 37.8 0.2 2.3 2 0 0 2 2 2 2 Fibronectin type III domain VWA_2 PF13519.6 KFP08352.1 - 6.9e-16 58.8 0.0 1.5e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Pur_ac_phosph_N PF16656.5 KFP08352.1 - 1.6e-05 25.4 1.4 0.24 12.0 0.2 3.5 3 1 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFP08352.1 - 0.00045 20.5 0.0 0.36 11.2 0.0 2.4 2 0 0 2 2 2 2 Interferon-alpha/beta receptor, fibronectin type III VWA_3 PF13768.6 KFP08352.1 - 0.0012 18.8 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KFP08352.1 - 0.039 13.3 0.2 0.24 10.7 0.1 2.3 2 1 0 2 2 2 0 VWA domain containing CoxE-like protein DUF2369 PF10179.9 KFP08352.1 - 0.11 12.9 0.0 6.9 7.1 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2369) DUF2852 PF11014.8 KFP08353.1 - 0.13 12.4 0.1 0.13 12.4 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) FtsX PF02687.21 KFP08353.1 - 0.19 12.2 10.3 0.26 11.8 10.3 1.3 1 0 0 1 1 1 0 FtsX-like permease family DUF3671 PF12420.8 KFP08353.1 - 3.9 7.6 6.3 5.7 7.1 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function Ribosomal_L20 PF00453.18 KFP08354.1 - 1.9e-34 118.0 3.8 2.4e-34 117.6 3.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 Cyclin_N PF00134.23 KFP08355.1 - 2.9e-14 52.9 1.1 2e-08 34.0 0.1 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP08355.1 - 1.6e-06 28.2 0.1 1.6e-06 28.2 0.1 2.2 3 0 0 3 3 3 1 Cyclin, C-terminal domain TFIIB PF00382.19 KFP08355.1 - 0.00032 20.7 0.4 0.28 11.3 0.1 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 KFP08355.1 - 0.0025 18.2 0.0 0.0071 16.7 0.0 1.9 2 0 0 2 2 2 1 Cyclin C-terminal domain DUF936 PF06075.12 KFP08355.1 - 8.5 5.2 29.2 11 4.8 29.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) adh_short PF00106.25 KFP08356.1 - 2.8e-30 105.2 0.1 3.7e-30 104.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP08356.1 - 6.3e-24 84.8 0.0 8.3e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP08356.1 - 4.7e-08 33.1 0.0 8.8e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 KR domain PCI PF01399.27 KFP08356.1 - 0.12 12.9 1.1 0.27 11.8 0.5 1.8 1 1 1 2 2 2 0 PCI domain ADH_zinc_N PF00107.26 KFP08356.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.4 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DUF1713 PF08213.11 KFP08357.1 - 1.1e-10 41.2 20.2 1.1e-10 41.2 20.2 2.2 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) V-set PF07686.17 KFP08358.1 - 2e-29 101.9 0.1 2.5e-17 63.0 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.25 KFP08358.1 - 5.2e-10 39.4 1.7 0.002 18.2 0.2 3.7 2 2 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP08358.1 - 4.6e-08 33.0 0.0 0.014 15.5 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP08358.1 - 8e-08 32.8 1.7 0.0083 16.7 0.1 3.7 2 2 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP08358.1 - 0.0001 22.6 2.4 0.049 14.0 0.1 3.4 2 1 0 2 2 2 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFP08358.1 - 0.0028 17.7 0.0 1.7 8.7 0.0 2.5 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFP08358.1 - 0.0075 15.8 0.1 4.3 7.0 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain V-set_CD47 PF08204.11 KFP08358.1 - 0.014 15.4 0.1 0.7 9.9 0.0 2.5 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain Receptor_2B4 PF11465.8 KFP08358.1 - 0.023 14.9 0.1 2.3 8.5 0.1 2.7 2 1 0 2 2 2 0 Natural killer cell receptor 2B4 FixQ PF05545.11 KFP08358.1 - 0.065 13.2 0.7 0.13 12.3 0.7 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Dsh_C PF12316.8 KFP08359.1 - 1.3e-70 238.0 30.1 1.3e-70 238.0 30.1 2.8 3 1 0 3 3 3 1 Segment polarity protein dishevelled (Dsh) C terminal Dishevelled PF02377.15 KFP08359.1 - 1.2e-68 230.6 26.6 1.2e-68 230.6 26.6 2.8 3 0 0 3 3 3 1 Dishevelled specific domain PDZ PF00595.24 KFP08359.1 - 1.2e-19 70.4 0.3 2e-19 69.7 0.3 1.4 1 0 0 1 1 1 1 PDZ domain DEP PF00610.21 KFP08359.1 - 1.8e-16 60.0 0.1 3.4e-16 59.1 0.1 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ_6 PF17820.1 KFP08359.1 - 4.8e-05 23.1 0.1 8.3e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP08359.1 - 0.0028 18.0 0.2 0.0058 16.9 0.2 1.5 1 0 0 1 1 1 1 PDZ domain Shufflon_N PF04917.12 KFP08359.1 - 0.036 13.5 0.1 0.06 12.8 0.1 1.2 1 0 0 1 1 1 0 Bacterial shufflon protein, N-terminal constant region SPT6_acidic PF14632.6 KFP08359.1 - 0.49 11.0 8.1 0.31 11.7 1.7 2.6 2 0 0 2 2 2 0 Acidic N-terminal SPT6 GLTP PF08718.11 KFP08360.1 - 3.9e-38 131.1 0.0 5.7e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) PseudoU_synth_1 PF01416.20 KFP08361.1 - 1.6e-35 121.8 0.0 1.6e-29 102.5 0.0 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase BAR_3 PF16746.5 KFP08362.1 - 3.2e-78 262.7 10.8 5.9e-78 261.9 10.8 1.4 1 0 0 1 1 1 1 BAR domain of APPL family ArfGap PF01412.18 KFP08362.1 - 2.2e-40 137.4 0.6 2.2e-40 137.4 0.6 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.29 KFP08362.1 - 3.2e-14 53.3 0.2 3.2e-14 53.3 0.2 2.1 2 0 0 2 2 1 1 PH domain Ank_2 PF12796.7 KFP08362.1 - 3.7e-12 46.7 0.6 3.4e-07 30.7 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP08362.1 - 8.6e-12 45.1 0.7 2.2e-08 34.2 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP08362.1 - 9.9e-11 42.0 0.4 2.7e-05 24.6 0.0 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KFP08362.1 - 2.7e-07 30.7 0.7 0.039 14.4 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KFP08362.1 - 3e-07 30.2 0.7 0.0065 16.9 0.0 4.7 4 0 0 4 4 4 1 Ankyrin repeat BAR PF03114.18 KFP08362.1 - 0.0035 17.0 7.1 0.0071 16.0 7.1 1.5 1 0 0 1 1 1 1 BAR domain PH_11 PF15413.6 KFP08362.1 - 0.016 15.6 5.7 0.097 13.1 2.5 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain PH_8 PF15409.6 KFP08362.1 - 0.11 12.8 0.1 0.39 11.0 0.1 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain Exonuc_VII_L PF02601.15 KFP08362.1 - 0.12 11.9 2.6 0.25 10.9 2.6 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit PilX PF13681.6 KFP08362.1 - 0.26 11.7 0.8 0.72 10.3 0.1 2.0 2 0 0 2 2 2 0 Type IV pilus assembly protein PilX C-term UQ_con PF00179.26 KFP08363.1 - 1.2e-18 67.1 0.0 1.8e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme C1q PF00386.21 KFP08364.1 - 3.2e-06 27.4 0.0 5.9e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 C1q domain Collagen PF01391.18 KFP08364.1 - 0.0029 17.3 4.3 0.0045 16.7 4.3 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) TNF PF00229.18 KFP08364.1 - 0.021 14.8 0.0 0.045 13.7 0.0 1.5 1 1 0 1 1 1 0 TNF(Tumour Necrosis Factor) family Peptidase_M13_N PF05649.13 KFP08365.1 - 2.5e-118 396.1 5.5 2.5e-118 396.1 5.5 1.4 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFP08365.1 - 3.4e-72 242.3 0.2 3.4e-72 242.3 0.2 1.6 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M48 PF01435.18 KFP08365.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 Peptidase family M48 RE_Eco47II PF09553.10 KFP08365.1 - 0.063 12.9 0.2 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 Eco47II restriction endonuclease Pox_I5 PF04713.12 KFP08365.1 - 0.086 12.9 0.6 0.19 11.8 0.6 1.4 1 0 0 1 1 1 0 Poxvirus protein I5 Ly49 PF08391.10 KFP08365.1 - 2.5 8.5 6.0 11 6.4 0.3 2.7 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region TPR_2 PF07719.17 KFP08366.1 - 4.1e-23 79.6 16.5 0.028 14.5 0.0 9.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_1 PF00515.28 KFP08366.1 - 7.4e-18 63.5 24.7 0.022 14.6 0.1 10.0 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_16 PF13432.6 KFP08366.1 - 1.4e-12 48.1 10.7 0.0077 16.9 0.1 6.2 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFP08366.1 - 2.2e-12 47.3 12.7 0.0016 18.9 0.6 7.3 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 KFP08366.1 - 1.9e-10 40.8 8.5 0.0009 19.3 0.0 6.4 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFP08366.1 - 7.2e-10 39.0 21.6 0.11 12.9 0.5 7.9 6 2 2 8 8 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP08366.1 - 2.7e-09 37.1 23.1 0.0035 17.5 0.2 6.6 6 2 0 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KFP08366.1 - 1e-08 34.7 11.7 0.47 10.2 0.0 6.5 8 1 1 9 9 7 3 TPR repeat TPR_8 PF13181.6 KFP08366.1 - 6.6e-08 32.2 18.0 1.3 9.4 0.1 9.5 10 1 1 11 11 10 2 Tetratricopeptide repeat TPR_20 PF14561.6 KFP08366.1 - 1.3e-07 31.8 9.6 0.015 15.7 0.1 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFP08366.1 - 1.2e-06 28.8 16.6 0.11 13.3 0.4 7.5 6 2 2 8 8 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 KFP08366.1 - 2.7e-06 26.8 4.2 0.0073 15.5 0.4 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFP08366.1 - 4.1e-05 23.9 5.5 10 7.0 0.0 7.4 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFP08366.1 - 6.9e-05 22.6 16.7 2.9 7.9 0.1 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFP08366.1 - 0.00054 20.2 7.9 0.38 11.2 0.0 6.9 9 0 0 9 9 6 1 Tetratricopeptide repeat Coatomer_E PF04733.14 KFP08366.1 - 0.001 18.5 1.4 2.8 7.3 0.0 4.0 4 1 1 5 5 5 1 Coatomer epsilon subunit SNAP PF14938.6 KFP08366.1 - 0.0042 16.6 1.4 0.0042 16.6 1.4 3.8 6 0 0 6 6 6 1 Soluble NSF attachment protein, SNAP Type_III_YscG PF09477.10 KFP08366.1 - 0.0062 16.6 0.4 4.9 7.3 0.0 3.7 3 0 0 3 3 3 1 Bacterial type II secretion system chaperone protein (type_III_yscG) SRP_TPR_like PF17004.5 KFP08366.1 - 0.014 15.5 7.3 3.4 7.7 0.6 4.8 3 1 1 4 4 4 0 Putative TPR-like repeat HrpB1_HrpK PF09613.10 KFP08366.1 - 0.1 12.2 1.9 0.31 10.7 0.1 2.8 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_4 PF07721.14 KFP08366.1 - 0.19 12.5 0.0 0.19 12.5 0.0 4.5 6 0 0 6 6 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP08366.1 - 0.99 9.6 8.5 27 5.1 0.0 5.3 7 0 0 7 7 4 0 Tetratricopeptide repeat TPR_5 PF12688.7 KFP08366.1 - 1 9.6 6.8 5.2 7.3 0.1 4.3 6 0 0 6 6 5 0 Tetratrico peptide repeat TPR_21 PF09976.9 KFP08366.1 - 1.6 8.4 16.4 2.7 7.7 0.1 5.0 5 2 1 6 6 5 0 Tetratricopeptide repeat-like domain zf-C2H2 PF00096.26 KFP08368.1 - 6e-49 161.9 83.3 5.1e-07 29.8 1.4 10.5 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP08368.1 - 2.8e-32 108.6 76.9 0.00082 20.0 0.6 10.5 10 0 0 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP08368.1 - 1e-27 95.3 78.8 2.9e-08 33.8 1.2 11.7 13 0 0 13 13 13 6 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFP08368.1 - 5e-12 45.8 55.4 0.061 13.6 0.2 10.3 10 0 0 10 10 10 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP08368.1 - 1.4e-08 34.5 67.8 0.059 13.4 0.2 10.2 10 0 0 10 10 10 8 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFP08368.1 - 1.7e-08 34.1 53.8 0.058 13.2 2.8 9.3 10 0 0 10 10 10 6 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KFP08368.1 - 1.2e-07 31.4 56.4 4.3e-05 23.2 2.4 8.7 9 1 0 9 9 8 5 C2H2-type zinc-finger domain zf-BED PF02892.15 KFP08368.1 - 0.00064 19.7 0.5 0.00064 19.7 0.5 7.9 3 3 5 8 8 8 3 BED zinc finger zf-C2H2_8 PF15909.5 KFP08368.1 - 0.0039 17.5 41.6 0.067 13.5 8.1 5.5 2 1 3 5 5 5 3 C2H2-type zinc ribbon zf-met PF12874.7 KFP08368.1 - 0.012 16.0 51.2 0.36 11.3 0.4 9.5 9 0 0 9 9 9 0 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 KFP08368.1 - 0.12 13.1 40.2 0.2 12.4 0.2 6.6 3 1 1 5 5 4 0 zinc-ribbon family Ribosomal_L31 PF01197.18 KFP08368.1 - 0.27 11.5 9.6 5.5 7.3 1.2 4.9 3 1 1 4 4 4 0 Ribosomal protein L31 GAGA PF09237.11 KFP08368.1 - 4.3 7.2 26.4 2 8.3 0.4 5.9 4 1 2 6 6 6 0 GAGA factor zf-LYAR PF08790.11 KFP08368.1 - 7.4 6.6 23.4 3.6 7.6 0.3 6.9 6 1 0 6 6 6 0 LYAR-type C2HC zinc finger RhoGEF PF00621.20 KFP08369.1 - 1.9e-36 126.0 2.3 2.7e-36 125.5 2.3 1.2 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.6 KFP08369.1 - 2.8e-11 43.1 0.1 7e-11 41.8 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP08369.1 - 6.2e-09 35.3 0.4 1.5e-08 34.1 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFP08369.1 - 3.6e-07 29.8 0.0 8.8e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 KFP08369.1 - 3e-06 27.7 0.0 7.3e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 KFP08369.1 - 0.00029 20.8 0.0 0.00095 19.2 0.0 1.8 1 0 0 1 1 1 1 PH domain HATPase_c_3 PF13589.6 KFP08369.1 - 0.15 11.9 0.0 0.84 9.5 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase hSac2 PF12456.8 KFP08370.1 - 1.3e-26 92.6 0.0 2.2e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase ANAPC4_WD40 PF12894.7 KFP08371.1 - 5.6e-12 45.8 0.9 0.0011 19.3 0.0 6.7 2 2 6 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFP08371.1 - 1.6e-08 35.1 7.1 0.0057 17.5 0.0 7.8 7 1 0 7 7 7 1 WD domain, G-beta repeat eIF2A PF08662.11 KFP08371.1 - 3.4e-08 33.6 0.1 0.089 12.7 0.0 4.0 2 2 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KFP08371.1 - 0.015 13.3 3.8 0.94 7.4 0.1 2.8 2 1 2 4 4 4 0 IKI3 family P53 PF00870.18 KFP08372.1 - 1.2e-64 217.7 0.0 1.9e-64 217.0 0.0 1.4 1 0 0 1 1 1 1 P53 DNA-binding domain P53_tetramer PF07710.11 KFP08372.1 - 3.5e-18 64.6 0.8 7.8e-18 63.5 0.8 1.6 1 0 0 1 1 1 1 P53 tetramerisation motif SAM_2 PF07647.17 KFP08372.1 - 2.6e-08 33.9 0.0 4.8e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFP08372.1 - 0.0026 18.1 0.0 0.0049 17.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) ATG16 PF08614.11 KFP08373.1 - 0.014 15.6 27.3 0.2 11.8 6.2 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) LMWPc PF01451.21 KFP08373.1 - 0.031 14.7 5.1 0.052 13.9 3.5 2.1 1 1 1 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase MAD PF05557.13 KFP08373.1 - 0.13 10.6 29.5 0.66 8.3 16.0 2.2 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF16 PF01519.16 KFP08373.1 - 0.56 10.7 25.1 0.31 11.5 10.2 2.9 1 1 2 3 3 3 0 Protein of unknown function DUF16 Uso1_p115_C PF04871.13 KFP08373.1 - 1.1 9.6 24.2 1.4 9.3 9.6 2.6 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1664 PF07889.12 KFP08373.1 - 1.2 9.2 21.3 1.3 9.1 4.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) USP8_interact PF08941.10 KFP08373.1 - 1.2 8.9 19.8 0.92 9.3 7.3 2.4 1 1 1 2 2 2 0 USP8 interacting Cnn_1N PF07989.11 KFP08373.1 - 1.5 9.1 24.1 0.068 13.3 5.7 3.7 3 1 1 4 4 4 0 Centrosomin N-terminal motif 1 PspA_IM30 PF04012.12 KFP08373.1 - 1.5 8.4 32.5 1.2 8.6 18.5 2.1 1 1 1 2 2 2 0 PspA/IM30 family HAP1_N PF04849.13 KFP08373.1 - 1.5 7.9 31.4 0.13 11.4 25.8 1.9 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Peptidase_M75 PF09375.10 KFP08373.1 - 1.7 8.1 11.9 0.14 11.6 4.3 2.4 1 1 1 2 2 2 0 Imelysin Lebercilin PF15619.6 KFP08373.1 - 2 8.0 33.9 0.098 12.3 12.6 2.5 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF724 PF05266.14 KFP08373.1 - 2.2 8.1 24.8 1.8 8.3 8.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) GAS PF13851.6 KFP08373.1 - 3.6 6.9 32.2 2.9 7.2 6.8 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding SlyX PF04102.12 KFP08373.1 - 4.2 8.1 31.4 0.66 10.6 12.4 3.5 3 2 0 3 3 2 0 SlyX KxDL PF10241.9 KFP08373.1 - 4.4 7.6 28.8 1.1 9.6 5.0 3.6 3 1 1 4 4 4 0 Uncharacterized conserved protein DUF3847 PF12958.7 KFP08373.1 - 5 7.3 29.1 0.096 12.8 5.8 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3847) DivIC PF04977.15 KFP08373.1 - 5.3 6.9 28.8 2.1 8.2 6.4 3.7 1 1 1 3 3 3 0 Septum formation initiator Spc7 PF08317.11 KFP08373.1 - 5.4 5.8 28.5 5.1 5.9 26.1 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 KFP08373.1 - 5.9 7.0 25.1 0.41 10.7 3.9 3.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 KFP08373.1 - 7.6 6.6 29.9 7.5 6.6 7.2 2.8 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF5082 PF16888.5 KFP08373.1 - 9.8 6.5 22.4 0.42 10.9 5.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) B3_4 PF03483.17 KFP08374.1 - 1.1e-09 38.2 0.0 2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain LRR_4 PF12799.7 KFP08374.1 - 0.00061 20.1 0.2 0.0047 17.3 0.1 2.6 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) UVR PF02151.19 KFP08375.1 - 0.0027 17.4 15.7 0.071 12.9 3.2 2.8 2 0 0 2 2 2 2 UvrB/uvrC motif CLASP_N PF12348.8 KFP08375.1 - 0.014 15.0 0.1 0.028 14.0 0.1 1.5 1 0 0 1 1 1 0 CLASP N terminal EAV_GS PF01309.18 KFP08375.1 - 0.17 11.5 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 Equine arteritis virus small envelope glycoprotein zf_UBZ PF18439.1 KFP08375.1 - 0.41 10.3 10.5 1 9.0 0.6 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF1272 PF06906.11 KFP08375.1 - 9.1 6.5 7.1 4.3 7.5 1.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DFF40 PF09230.10 KFP08376.1 - 5e-88 294.5 5.0 5.5e-88 294.4 5.0 1.0 1 0 0 1 1 1 1 DNA fragmentation factor 40 kDa Ribosomal_L27_C PF18471.1 KFP08376.1 - 0.01 15.3 0.6 0.02 14.3 0.3 1.6 2 0 0 2 2 2 0 Ribosomal L27 protein C-terminal domain UPF0688 PF15772.5 KFP08377.1 - 1.7e-49 169.2 11.3 2e-49 168.9 11.3 1.0 1 0 0 1 1 1 1 UPF0688 family AJAP1_PANP_C PF15298.6 KFP08378.1 - 1.5e-48 165.6 1.0 1.8e-48 165.4 1.0 1.0 1 0 0 1 1 1 1 AJAP1/PANP C-terminus Stomagen PF16851.5 KFP08378.1 - 0.0042 17.1 0.2 0.0071 16.3 0.2 1.4 1 0 0 1 1 1 1 Stomagen ASH PF15780.5 KFP08379.1 - 0.091 13.0 0.0 0.51 10.6 0.0 2.0 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Aldo_ket_red PF00248.21 KFP08380.1 - 8e-32 110.6 0.0 8.8e-32 110.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KFP08381.1 - 2.7e-14 53.1 0.0 3e-14 52.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SMI1_KNR4 PF09346.10 KFP08381.1 - 0.032 14.6 0.0 0.032 14.6 0.0 1.1 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) MRF_C1 PF13887.6 KFP08381.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 CHDCT2 PF08074.11 KFP08382.1 - 1.6e-85 285.6 0.1 3.6e-85 284.4 0.1 1.7 1 0 0 1 1 1 1 CHDCT2 (NUC038) domain SNF2_N PF00176.23 KFP08382.1 - 5.8e-61 206.1 0.1 5.8e-61 206.1 0.1 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF1086 PF06461.11 KFP08382.1 - 8.6e-58 194.1 0.1 4.7e-57 191.7 0.0 2.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1086) DUF1087 PF06465.13 KFP08382.1 - 8.6e-27 93.0 5.8 5.2e-26 90.5 5.8 2.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) CHDNT PF08073.12 KFP08382.1 - 1.4e-25 89.0 0.4 3.5e-25 87.7 0.4 1.7 1 0 0 1 1 1 1 CHDNT (NUC034) domain Helicase_C PF00271.31 KFP08382.1 - 5.3e-21 75.1 0.0 1.1e-20 74.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 KFP08382.1 - 3e-17 62.2 4.9 1.9e-11 43.6 0.7 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 KFP08382.1 - 5.8e-11 42.1 7.0 1.2e-10 41.1 7.0 1.6 1 0 0 1 1 1 1 PHD-finger ResIII PF04851.15 KFP08382.1 - 3.4e-08 33.7 0.0 3.4e-08 33.7 0.0 2.3 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KFP08382.1 - 0.00027 20.2 0.0 0.00027 20.2 0.0 2.8 2 1 0 2 2 1 1 Class II histone deacetylase complex subunits 2 and 3 zf-HC5HC2H PF13771.6 KFP08382.1 - 0.0095 16.2 0.5 0.024 14.9 0.5 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFP08382.1 - 0.11 12.7 0.2 0.29 11.3 0.2 1.7 1 0 0 1 1 1 0 PHD-zinc-finger like domain AAA_22 PF13401.6 KFP08382.1 - 0.16 12.2 0.0 0.51 10.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain Ribosomal_L22e PF01776.17 KFP08383.1 - 1.1e-53 180.2 1.0 1.4e-53 179.9 1.0 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family zf-B_box PF00643.24 KFP08384.1 - 1.5e-06 28.3 7.5 1.5e-06 28.3 7.5 4.1 3 1 0 3 3 2 2 B-box zinc finger zf-RING_UBOX PF13445.6 KFP08384.1 - 1.8e-06 27.8 9.7 1e-05 25.4 9.7 2.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFP08384.1 - 2.5e-05 24.1 10.1 2.5e-05 24.1 10.1 4.0 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) AIP3 PF03915.13 KFP08384.1 - 2.5e-05 23.6 11.2 0.00012 21.3 2.2 2.1 2 0 0 2 2 2 2 Actin interacting protein 3 zf-RING_5 PF14634.6 KFP08384.1 - 0.00014 21.8 10.8 0.00014 21.8 10.8 3.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFP08384.1 - 0.00061 19.6 10.2 0.00061 19.6 10.2 4.4 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) ARA70 PF12489.8 KFP08384.1 - 0.0013 18.9 1.0 0.0013 18.9 1.0 2.1 2 1 0 2 2 2 1 Nuclear coactivator zf-RING_2 PF13639.6 KFP08384.1 - 0.0032 17.7 10.3 0.0032 17.7 10.3 3.5 4 0 0 4 4 2 1 Ring finger domain DUF3583 PF12126.8 KFP08384.1 - 0.0072 15.8 5.8 0.0072 15.8 5.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3583) Tht1 PF04163.12 KFP08384.1 - 0.011 14.5 3.5 0.031 13.0 0.2 2.1 2 0 0 2 2 2 0 Tht1-like nuclear fusion protein IL10 PF00726.17 KFP08384.1 - 0.014 14.9 1.5 0.014 14.9 1.5 2.9 2 2 0 2 2 2 0 Interleukin 10 Thioredoxin_7 PF13899.6 KFP08384.1 - 0.015 15.4 0.2 0.054 13.7 0.1 2.0 1 1 1 2 2 2 0 Thioredoxin-like zf-CHC2 PF01807.20 KFP08384.1 - 0.022 14.6 1.9 0.043 13.6 0.2 2.4 2 0 0 2 2 2 0 CHC2 zinc finger DUF3400 PF11880.8 KFP08384.1 - 0.033 13.7 0.5 0.066 12.8 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) Exonuc_VII_L PF02601.15 KFP08384.1 - 0.14 11.7 15.4 0.021 14.4 4.2 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit AAA_15 PF13175.6 KFP08384.1 - 0.31 10.7 3.2 0.5 10.0 0.3 2.0 2 0 0 2 2 2 0 AAA ATPase domain ApoLp-III PF07464.11 KFP08384.1 - 1.3 9.1 11.7 1.1 9.4 3.0 3.1 2 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) V-SNARE PF05008.15 KFP08384.1 - 1.9 8.9 12.6 2.4 8.6 2.3 3.5 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Fib_alpha PF08702.10 KFP08384.1 - 1.9 8.6 18.2 1.1 9.4 2.5 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 KFP08384.1 - 2.4 8.2 8.1 0.6 10.1 0.9 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1759 PF03564.15 KFP08384.1 - 4.5 7.2 7.5 0.56 10.1 0.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1759) Muted PF14942.6 KFP08384.1 - 5.4 7.4 14.7 0.41 11.0 4.2 2.5 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF4709 PF15821.5 KFP08384.1 - 9.6 6.5 15.1 1.3 9.4 3.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) ICMT PF04140.14 KFP08385.1 - 1.7e-34 118.1 0.1 2.8e-34 117.4 0.1 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KFP08385.1 - 3.8e-08 33.7 0.5 7.1e-08 32.8 0.5 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 KFP08385.1 - 0.019 14.5 0.2 0.023 14.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) 4HBT PF03061.22 KFP08386.1 - 4.9e-33 113.3 1.5 6.1e-16 58.6 0.1 2.2 2 0 0 2 2 2 2 Thioesterase superfamily tRNA_anti-codon PF01336.25 KFP08386.1 - 0.00013 21.9 0.0 0.0027 17.7 0.0 2.3 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain RhoGEF PF00621.20 KFP08388.1 - 2.1e-34 119.4 0.0 2.9e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain RBD PF02196.15 KFP08388.1 - 0.015 15.4 0.0 0.038 14.1 0.0 1.7 1 0 0 1 1 1 0 Raf-like Ras-binding domain UNC-79 PF14776.6 KFP08388.1 - 0.018 13.9 1.6 0.028 13.2 1.6 1.2 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 CLP1_P PF16575.5 KFP08389.1 - 4.7e-15 55.9 0.0 7.3e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 KFP08389.1 - 0.035 14.5 0.0 0.082 13.3 0.0 1.6 1 0 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 ANF_receptor PF01094.28 KFP08390.1 - 2.4e-50 171.6 0.0 3.3e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 KFP08390.1 - 5.3e-15 55.8 8.5 9e-15 55.0 8.5 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 KFP08390.1 - 1.9e-12 46.9 15.3 1.9e-12 46.9 15.3 2.0 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.6 KFP08390.1 - 3.6e-07 30.2 0.0 6.9e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Periplasmic binding protein PIG-P PF08510.12 KFP08390.1 - 0.18 11.7 0.8 0.6 10.0 0.4 2.1 2 0 0 2 2 2 0 PIG-P Sp38 PF07354.12 KFP08390.1 - 0.8 9.1 9.9 1.8 7.9 9.9 1.5 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) PHD PF00628.29 KFP08391.1 - 3.6e-08 33.2 8.2 5.9e-08 32.5 8.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KFP08391.1 - 4e-06 26.3 5.3 6.9e-06 25.5 5.3 1.4 1 0 0 1 1 1 1 PHD-finger zf-C4H2 PF10146.9 KFP08391.1 - 0.0015 18.9 0.1 0.0023 18.3 0.1 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein zf-HC5HC2H PF13771.6 KFP08391.1 - 0.016 15.5 1.1 0.031 14.5 1.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain C1_1 PF00130.22 KFP08391.1 - 0.017 15.0 2.0 0.017 15.0 2.0 1.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_9 PF13901.6 KFP08391.1 - 0.78 9.7 6.8 1.4 8.9 6.8 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon DUF3395 PF11875.8 KFP08392.1 - 1.2e-46 158.4 0.4 1.2e-46 158.4 0.4 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 KFP08392.1 - 1.8e-17 63.2 1.7 3.8e-17 62.1 0.5 2.1 2 0 0 2 2 2 1 DnaJ domain DUF4736 PF15883.5 KFP08392.1 - 0.09 12.5 1.4 0.17 11.6 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) GDA1_CD39 PF01150.17 KFP08392.1 - 0.13 10.8 0.1 0.2 10.2 0.1 1.1 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family CG-1 PF03859.16 KFP08393.1 - 8.7e-34 115.8 1.1 2.6e-33 114.3 1.1 1.9 1 0 0 1 1 1 1 CG-1 domain TIG PF01833.24 KFP08393.1 - 7e-11 42.1 1.6 1.6e-10 40.9 0.2 2.4 2 0 0 2 2 2 1 IPT/TIG domain Ank_2 PF12796.7 KFP08393.1 - 1.2e-09 38.6 0.2 5e-05 23.8 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP08393.1 - 3.8e-05 23.9 0.9 0.53 10.7 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP08393.1 - 0.00025 21.3 0.6 0.94 10.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat IQ PF00612.27 KFP08393.1 - 0.0016 18.1 18.7 0.8 9.7 0.3 5.4 5 0 0 5 5 5 3 IQ calmodulin-binding motif Ank_4 PF13637.6 KFP08393.1 - 0.0079 16.8 1.3 0.7 10.5 0.1 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 KFP08393.1 - 0.013 15.9 0.4 3.4 8.3 0.1 2.8 2 0 0 2 2 2 0 Ankyrin repeat Synaptobrevin PF00957.21 KFP08394.1 - 9.4e-29 99.1 0.4 1.1e-28 98.8 0.4 1.0 1 0 0 1 1 1 1 Synaptobrevin MCU PF04678.13 KFP08394.1 - 0.021 14.9 0.1 0.023 14.8 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Urotensin_II PF02083.15 KFP08395.1 - 1.5e-06 27.5 1.0 2.6e-06 26.8 1.0 1.4 1 0 0 1 1 1 1 Urotensin II SieB PF14163.6 KFP08395.1 - 0.13 11.8 0.4 0.68 9.4 0.0 2.0 1 1 0 2 2 2 0 Super-infection exclusion protein B DJ-1_PfpI PF01965.24 KFP08396.1 - 2.4e-52 177.1 0.0 2.7e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KFP08396.1 - 0.00019 21.2 0.0 0.02 14.6 0.0 2.2 1 1 1 2 2 2 2 ThiJ/PfpI family-like GATase_3 PF07685.14 KFP08396.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.3 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Inhibitor_Mig-6 PF11555.8 KFP08397.1 - 1.6e-14 53.7 8.3 1.6e-14 53.7 8.3 3.5 3 0 0 3 3 3 2 EGFR receptor inhibitor Mig-6 GTPase_binding PF09027.10 KFP08397.1 - 0.00021 21.2 0.0 0.00048 20.1 0.0 1.6 1 0 0 1 1 1 1 GTPase binding MFS_1 PF07690.16 KFP08398.1 - 2.1e-08 33.5 5.1 2.5e-08 33.2 5.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Spermine_synth PF01564.17 KFP08399.1 - 1.3e-64 217.1 0.0 1.9e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_31 PF13847.6 KFP08399.1 - 1.2e-05 25.1 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP08399.1 - 0.00018 22.2 0.0 0.00073 20.2 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 KFP08399.1 - 0.053 13.5 0.1 0.11 12.4 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_30 PF05430.11 KFP08399.1 - 0.083 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 KFP08399.1 - 0.087 13.6 0.0 0.34 11.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Somatostatin PF03002.15 KFP08400.1 - 9.9e-12 44.5 7.1 1.5e-11 44.0 7.1 1.3 1 0 0 1 1 1 1 Somatostatin/Cortistatin family CUB PF00431.20 KFP08401.1 - 1.7e-19 70.2 0.1 2.4e-19 69.7 0.1 1.2 1 0 0 1 1 1 1 CUB domain EGF_CA PF07645.15 KFP08401.1 - 6.5e-08 32.6 7.2 1.3e-07 31.7 7.2 1.5 1 0 0 1 1 1 1 Calcium-binding EGF domain FXa_inhibition PF14670.6 KFP08401.1 - 9.9e-08 32.1 9.0 2.3e-07 31.0 9.0 1.7 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site EGF PF00008.27 KFP08401.1 - 0.00061 20.0 8.8 0.0014 18.9 8.8 1.6 1 0 0 1 1 1 1 EGF-like domain cEGF PF12662.7 KFP08401.1 - 0.0014 18.5 2.1 0.0014 18.5 2.1 2.4 2 0 0 2 2 2 1 Complement Clr-like EGF-like CUB_2 PF02408.20 KFP08401.1 - 0.046 13.5 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 CUB-like domain hEGF PF12661.7 KFP08401.1 - 2.4 8.9 10.9 0.76 10.5 7.6 2.0 2 1 0 2 2 2 0 Human growth factor-like EGF TDP43_N PF18694.1 KFP08402.1 - 1.6e-33 114.4 0.0 2.7e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain RRM_1 PF00076.22 KFP08402.1 - 3.2e-27 94.1 0.2 2.4e-15 56.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP08402.1 - 9.4e-08 32.1 0.6 0.0089 16.1 0.0 3.1 3 1 0 3 3 3 2 RNA recognition motif RL PF17797.1 KFP08402.1 - 0.00042 20.2 0.0 0.18 11.8 0.0 2.3 2 0 0 2 2 2 2 RL domain RRM_3 PF08777.11 KFP08402.1 - 0.0016 18.5 0.0 0.14 12.2 0.0 2.4 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 KFP08402.1 - 0.031 14.3 0.1 0.81 9.7 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Glucosaminidase PF01832.20 KFP08402.1 - 0.12 12.8 1.4 0.32 11.5 0.7 2.1 3 0 0 3 3 3 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase zf-C2H2 PF00096.26 KFP08405.1 - 0.036 14.5 26.6 0.11 13.0 2.8 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 KFP08405.1 - 0.04 14.2 13.2 3.1 8.2 2.1 3.5 1 1 2 3 3 3 0 C2H2-type zinc ribbon PPP4R2 PF09184.11 KFP08406.1 - 0.01 15.4 17.8 0.019 14.6 17.8 1.4 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.12 KFP08406.1 - 0.043 13.6 18.6 0.072 12.8 18.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KFP08406.1 - 0.077 11.2 20.7 0.11 10.8 20.7 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.8 KFP08406.1 - 0.59 10.4 23.6 1.5 9.0 23.6 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 BNIP3 PF06553.12 KFP08406.1 - 2.5 7.7 7.8 6.7 6.3 7.8 1.7 1 0 0 1 1 1 0 BNIP3 Sigma70_ner PF04546.13 KFP08406.1 - 7.5 6.4 19.7 12 5.7 19.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region BUD22 PF09073.10 KFP08406.1 - 9 5.5 21.9 18 4.5 21.9 1.4 1 0 0 1 1 1 0 BUD22 Pex14_N PF04695.13 KFP08407.1 - 4.9e-22 79.3 2.8 4.9e-22 79.3 2.8 4.0 2 2 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region HemX PF04375.14 KFP08407.1 - 0.00043 19.7 4.1 0.00043 19.7 4.1 1.6 2 0 0 2 2 2 1 HemX, putative uroporphyrinogen-III C-methyltransferase DUF948 PF06103.11 KFP08407.1 - 0.0047 17.2 0.4 0.011 15.9 0.4 1.6 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) Calici_PP_N PF08405.11 KFP08407.1 - 0.06 12.2 0.1 0.085 11.6 0.1 1.1 1 0 0 1 1 1 0 Viral polyprotein N-terminal Cob_adeno_trans PF01923.18 KFP08407.1 - 0.07 13.3 0.3 0.15 12.2 0.3 1.5 1 0 0 1 1 1 0 Cobalamin adenosyltransferase GLE1 PF07817.13 KFP08407.1 - 0.14 11.4 3.2 0.22 10.7 3.2 1.3 1 0 0 1 1 1 0 GLE1-like protein Phage_Gp23 PF10669.9 KFP08407.1 - 0.32 11.3 14.0 0.24 11.7 5.4 2.3 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) SPG4 PF17325.2 KFP08407.1 - 0.39 11.8 7.8 1.6 9.8 3.1 2.3 2 0 0 2 2 2 0 Stationary phase protein 4 TolA_bind_tri PF16331.5 KFP08407.1 - 0.63 10.2 11.5 0.73 9.9 6.9 2.7 2 1 1 3 3 2 0 TolA binding protein trimerisation Ribosomal_60s PF00428.19 KFP08407.1 - 2.2 8.9 6.7 1.1 9.9 3.9 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein CC2-LZ PF16516.5 KFP08407.1 - 2.6 8.4 12.9 0.071 13.5 1.6 2.3 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Nucleo_P87 PF07267.11 KFP08407.1 - 4.6 6.0 9.2 6.8 5.4 9.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4611 PF15387.6 KFP08407.1 - 5.8 7.2 13.3 8.2 6.7 7.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) AATF-Che1 PF13339.6 KFP08407.1 - 6.9 7.3 15.6 5.8e+02 1.1 15.6 2.3 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Fib_alpha PF08702.10 KFP08407.1 - 7.9 6.7 10.9 0.32 11.2 4.1 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TCP PF03634.13 KFP08407.1 - 8.5 6.9 11.1 20 5.7 10.9 1.8 1 1 0 1 1 1 0 TCP family transcription factor DFF-C PF09033.10 KFP08408.1 - 4.8e-57 192.5 18.1 1.1e-56 191.3 9.7 2.1 2 0 0 2 2 2 2 DNA Fragmentation factor 45kDa, C terminal domain CIDE-N PF02017.15 KFP08408.1 - 1.9e-21 75.9 0.1 1.9e-20 72.6 0.0 2.5 2 0 0 2 2 2 1 CIDE-N domain PSK_trans_fac PF07704.11 KFP08408.1 - 0.41 11.4 6.8 7.3 7.4 4.5 2.9 2 1 0 2 2 2 0 Rv0623-like transcription factor COG2 PF06148.11 KFP08408.1 - 0.6 10.2 7.3 0.1 12.7 2.8 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 V_ATPase_I PF01496.19 KFP08408.1 - 1.5 6.6 4.6 1.8 6.4 4.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Yuri_gagarin PF15934.5 KFP08408.1 - 1.8 8.3 12.0 0.11 12.3 6.7 1.6 2 0 0 2 2 2 0 Yuri gagarin CENP-S PF15630.6 KFP08409.1 - 6.5e-32 109.7 0.7 9.6e-32 109.2 0.7 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KFP08409.1 - 1.9e-09 37.6 1.0 2.4e-09 37.3 1.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KFP08409.1 - 1.2e-05 25.6 0.9 1.2e-05 25.6 0.9 2.0 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KFP08409.1 - 0.0013 18.7 0.5 0.0037 17.3 0.1 1.8 1 1 0 2 2 2 1 Bromodomain associated TFIID-31kDa PF02291.15 KFP08409.1 - 0.002 18.2 0.1 0.0024 17.9 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CFTR_R PF14396.6 KFP08409.1 - 0.0057 16.3 0.9 0.0069 16.0 0.9 1.2 1 0 0 1 1 1 1 Cystic fibrosis TM conductance regulator (CFTR), regulator domain 6PGD PF00393.19 KFP08410.1 - 1.2e-131 438.4 0.0 1.4e-131 438.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KFP08410.1 - 1.5e-49 168.2 0.0 2.1e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFP08410.1 - 0.11 12.7 0.1 0.3 11.3 0.0 1.8 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Kinesin PF00225.23 KFP08411.1 - 4.7e-116 387.4 0.4 7.5e-116 386.7 0.4 1.3 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 KFP08411.1 - 1.5e-85 285.9 0.2 1.5e-85 285.9 0.2 2.6 3 0 0 3 3 3 1 Kinesin-associated DUF3694 PF12473.8 KFP08411.1 - 9e-33 114.1 0.0 2.6e-32 112.6 0.0 1.9 1 0 0 1 1 1 1 Kinesin protein Microtub_bd PF16796.5 KFP08411.1 - 1.8e-25 89.6 0.1 7.2e-24 84.4 0.1 2.9 2 0 0 2 2 2 1 Microtubule binding PH PF00169.29 KFP08411.1 - 5.7e-13 49.3 0.1 2.5e-11 44.0 0.0 3.7 4 0 0 4 4 4 1 PH domain FHA PF00498.26 KFP08411.1 - 6.7e-08 32.8 0.3 2.7e-07 30.8 0.1 2.2 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KFP08411.1 - 0.0019 18.5 0.0 0.0055 17.0 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain KIF1B PF12423.8 KFP08411.1 - 0.024 15.1 0.7 0.024 15.1 0.7 2.6 2 0 0 2 2 2 0 Kinesin protein 1B Ufd2P_core PF10408.9 KFP08412.1 - 4.3e-202 673.1 14.4 5.6e-202 672.7 14.4 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KFP08412.1 - 1.1e-23 83.1 0.8 3e-23 81.8 0.3 2.1 2 0 0 2 2 2 1 U-box domain DUF4568 PF15132.6 KFP08412.1 - 0.24 10.7 2.2 1.1 8.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4568) Lipocalin PF00061.23 KFP08413.1 - 6.9e-19 68.5 0.8 7.4e-19 68.4 0.8 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 KFP08413.1 - 2.2e-05 24.4 0.3 2.6e-05 24.2 0.3 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Glyco_hydro_43 PF04616.14 KFP08413.1 - 0.082 12.2 0.0 0.099 11.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 43 CTP_transf_like PF01467.26 KFP08414.1 - 1.1e-33 116.5 0.1 2.9e-33 115.1 0.1 1.6 1 1 0 1 1 1 1 Cytidylyltransferase-like ChapFlgA PF13144.6 KFP08414.1 - 0.062 13.4 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Chaperone for flagella basal body P-ring formation ICAT PF06384.11 KFP08415.1 - 3.3e-32 110.6 0.2 3.3e-32 110.6 0.2 2.3 2 1 0 2 2 2 1 Beta-catenin-interacting protein ICAT CAMP_factor PF07373.11 KFP08415.1 - 0.00035 20.2 1.1 0.00052 19.7 1.1 1.3 1 0 0 1 1 1 1 CAMP factor (Cfa) Serine_rich PF08824.10 KFP08415.1 - 0.0037 17.3 1.7 0.0062 16.6 1.7 1.4 1 0 0 1 1 1 1 Serine rich protein interaction domain GvpG PF05120.12 KFP08415.1 - 0.0095 15.9 11.7 0.022 14.8 0.4 2.4 2 0 0 2 2 2 1 Gas vesicle protein G DUF3313 PF11769.8 KFP08415.1 - 0.046 13.5 0.1 0.095 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) Importin_rep_6 PF18829.1 KFP08415.1 - 0.053 13.7 0.6 0.087 13.0 0.6 1.4 1 0 0 1 1 1 0 Importin repeat 6 Spc7 PF08317.11 KFP08415.1 - 0.08 11.8 9.1 0.11 11.4 9.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein CK2S PF15011.6 KFP08415.1 - 0.092 12.6 10.1 0.63 9.9 0.1 3.0 1 1 1 3 3 3 0 Casein Kinase 2 substrate WXG100 PF06013.12 KFP08415.1 - 0.22 11.8 2.8 0.5 10.6 0.9 2.5 2 2 0 2 2 2 0 Proteins of 100 residues with WXG Laminin_II PF06009.12 KFP08415.1 - 0.24 11.4 6.2 2.1 8.4 0.8 2.9 2 1 1 3 3 3 0 Laminin Domain II Cauli_AT PF03233.13 KFP08415.1 - 0.32 10.9 3.1 0.71 9.8 3.1 1.5 1 0 0 1 1 1 0 Aphid transmission protein NPV_P10 PF05531.12 KFP08415.1 - 0.44 11.0 4.1 1.4 9.4 3.4 2.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4254 PF14063.6 KFP08415.1 - 0.5 10.2 6.5 0.47 10.2 1.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4254) FlxA PF14282.6 KFP08415.1 - 0.58 10.2 14.4 0.13 12.3 8.9 2.3 2 1 1 3 3 3 0 FlxA-like protein Baculo_p24 PF05073.12 KFP08415.1 - 1 9.1 4.8 14 5.4 2.7 2.1 1 1 1 2 2 2 0 Baculovirus P24 capsid protein Allexi_40kDa PF05549.11 KFP08415.1 - 1 8.8 4.0 1.1 8.8 3.1 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF2408 PF10303.9 KFP08415.1 - 1.1 9.8 8.3 0.71 10.4 5.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) XhlA PF10779.9 KFP08415.1 - 3.4 7.9 7.3 22 5.3 7.3 2.2 1 1 0 1 1 1 0 Haemolysin XhlA DUF1664 PF07889.12 KFP08415.1 - 5.4 7.1 8.1 6.2 6.9 4.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ICAT PF06384.11 KFP08416.1 - 2.5e-19 69.3 0.0 2.6e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 Beta-catenin-interacting protein ICAT DUF3140 PF11338.8 KFP08416.1 - 0.14 12.6 0.0 0.17 12.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) Cadherin PF00028.17 KFP08417.1 - 8.1e-15 55.0 0.0 5.7e-07 29.9 0.0 2.8 2 0 0 2 2 2 2 Cadherin domain Laminin_G_3 PF13385.6 KFP08417.1 - 2.9e-05 24.3 0.0 6.6e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily CDC45 PF02724.14 KFP08417.1 - 9.7e-05 20.9 2.5 0.00013 20.4 2.5 1.2 1 0 0 1 1 1 1 CDC45-like protein Laminin_G_2 PF02210.24 KFP08417.1 - 0.0013 19.3 0.3 0.012 16.2 0.0 2.7 3 0 0 3 3 3 1 Laminin G domain V_ATPase_I PF01496.19 KFP08417.1 - 0.026 12.5 1.6 0.039 11.9 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 KFP08417.1 - 0.078 12.7 0.3 0.16 11.7 0.3 1.4 1 0 0 1 1 1 0 Connexin SID-1_RNA_chan PF13965.6 KFP08417.1 - 0.1 11.0 0.5 0.15 10.4 0.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Zip PF02535.22 KFP08417.1 - 0.15 11.3 2.6 0.24 10.6 2.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RasGAP PF00616.19 KFP08417.1 - 1.6 8.4 3.7 2.9 7.5 3.7 1.4 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase TRAP_alpha PF03896.16 KFP08417.1 - 2.4 7.3 6.9 5.4 6.1 6.9 1.6 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PI3_PI4_kinase PF00454.27 KFP08418.1 - 1.5e-59 201.9 0.1 4.1e-59 200.4 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KFP08418.1 - 1.2e-54 184.5 3.4 2.3e-54 183.6 3.4 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_p85B PF02192.16 KFP08418.1 - 2.6e-30 104.0 0.0 8.7e-30 102.3 0.0 2.0 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain PI3K_rbd PF00794.18 KFP08418.1 - 2.4e-24 85.6 0.0 1.1e-23 83.4 0.0 2.2 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 KFP08418.1 - 2.9e-23 82.4 0.0 6.7e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 KFP08418.1 - 0.012 15.0 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Yae1_N PF09811.9 KFP08419.1 - 2.1e-07 30.5 58.3 1.8e+04 -35.5 58.3 6.3 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Galactosyl_T PF01762.21 KFP08420.1 - 1.4e-29 103.3 0.0 1.9e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase EF-hand_1 PF00036.32 KFP08421.1 - 3.4e-19 66.9 4.9 0.00047 19.5 0.0 6.3 6 0 0 6 6 6 5 EF hand EF-hand_7 PF13499.6 KFP08421.1 - 2.5e-14 53.5 12.0 2.3e-05 24.7 0.0 4.7 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 KFP08421.1 - 3.3e-11 42.1 1.3 0.0016 17.9 0.0 4.6 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 KFP08421.1 - 8.7e-11 40.9 2.6 0.39 10.8 0.0 5.7 6 0 0 6 6 6 3 EF-hand domain EF-hand_8 PF13833.6 KFP08421.1 - 6.6e-07 29.1 5.3 0.0067 16.2 0.1 4.4 3 2 1 4 4 4 2 EF-hand domain pair Pex14_N PF04695.13 KFP08421.1 - 0.013 16.2 0.1 0.033 14.9 0.1 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SPARC_Ca_bdg PF10591.9 KFP08421.1 - 0.025 14.9 11.5 0.79 10.1 1.1 3.5 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region TNFR_c6 PF00020.18 KFP08422.1 - 3.6e-20 72.1 32.8 3.3e-07 30.6 9.1 3.4 3 1 0 3 3 3 3 TNFR/NGFR cysteine-rich region RANK_CRD_2 PF18278.1 KFP08422.1 - 0.0026 17.8 2.4 0.0026 17.8 2.4 2.6 2 2 0 2 2 2 1 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Ephrin_rec_like PF07699.13 KFP08422.1 - 0.47 10.3 24.3 0.067 13.0 2.5 3.2 2 1 1 3 3 3 0 Putative ephrin-receptor like TTL PF03133.15 KFP08423.1 - 5.5e-31 107.8 0.3 8.9e-31 107.1 0.3 1.4 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KFP08423.1 - 0.17 11.1 0.8 0.67 9.2 0.0 2.4 3 1 0 3 3 3 0 YheC/D like ATP-grasp DUF4501 PF14946.6 KFP08424.1 - 1.5e-29 103.4 0.6 1.5e-29 103.3 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4501) zf-RING_5 PF14634.6 KFP08425.1 - 5.1e-09 36.0 7.0 5.1e-09 36.0 7.0 2.0 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFP08425.1 - 1.1e-08 35.3 7.6 1.1e-08 35.3 7.6 2.2 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 KFP08425.1 - 6.2e-08 32.5 5.6 6.2e-08 32.5 5.6 2.5 2 1 1 3 3 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFP08425.1 - 2.2e-06 27.4 4.7 2.2e-06 27.4 4.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP08425.1 - 6.4e-06 26.0 7.7 6.4e-06 26.0 7.7 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFP08425.1 - 4.6e-05 23.5 7.0 0.00025 21.1 7.0 2.4 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KFP08425.1 - 0.00015 21.5 5.0 0.00036 20.2 5.0 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFP08425.1 - 0.003 17.3 10.5 0.003 17.3 10.5 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KFP08425.1 - 0.0084 15.9 5.6 0.026 14.3 5.6 1.8 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain UBM PF14377.6 KFP08425.1 - 0.016 14.6 0.5 0.033 13.7 0.5 1.5 1 0 0 1 1 1 0 Ubiquitin binding region Prok-RING_4 PF14447.6 KFP08425.1 - 0.08 12.8 11.2 0.066 13.1 7.8 2.6 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KFP08425.1 - 0.3 11.3 6.6 4.7 7.4 4.7 2.7 2 1 0 2 2 2 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KFP08425.1 - 0.37 11.1 7.1 2.4 8.5 7.1 2.4 1 1 0 1 1 1 0 RING-H2 zinc finger domain PH PF00169.29 KFP08427.1 - 1.1e-09 38.7 0.1 9.2e-05 22.9 0.0 2.5 2 1 0 2 2 2 2 PH domain DUF1908 PF08926.11 KFP08427.1 - 0.018 14.1 0.1 0.025 13.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) Kelch_1 PF01344.25 KFP08428.1 - 6.3e-79 259.4 16.1 3.8e-16 58.4 0.3 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFP08428.1 - 2.8e-43 144.8 5.2 2.3e-09 37.2 0.0 6.6 2 1 5 7 7 7 6 Kelch motif BACK PF07707.15 KFP08428.1 - 2.5e-38 130.3 0.1 5.5e-38 129.2 0.1 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 KFP08428.1 - 1.2e-33 115.6 0.6 2.4e-33 114.6 0.2 1.7 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.6 KFP08428.1 - 1.6e-26 92.0 15.2 7.7e-07 29.3 0.1 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KFP08428.1 - 4.1e-26 90.7 1.1 2.7e-06 27.3 0.0 6.3 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP08428.1 - 1.7e-25 88.0 2.5 0.00013 21.7 0.1 6.0 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 KFP08428.1 - 4.9e-09 36.0 5.5 0.1 12.6 0.0 5.5 5 0 0 5 5 5 3 Kelch motif XPA_C PF05181.12 KFP08428.1 - 0.11 12.5 0.3 27 4.8 0.0 2.9 3 0 0 3 3 3 0 XPA protein C-terminus BA14K PF07886.11 KFP08428.1 - 0.46 10.4 3.0 5.2 7.0 0.0 3.7 4 0 0 4 4 4 0 BA14K-like protein PQQ_3 PF13570.6 KFP08428.1 - 2.6 8.6 12.8 22 5.7 0.1 5.7 6 0 0 6 6 6 0 PQQ-like domain Noc2 PF03715.13 KFP08429.1 - 5.9e-114 380.3 7.0 5.9e-114 380.3 7.0 1.6 2 0 0 2 2 2 1 Noc2p family Isy1 PF06246.12 KFP08429.1 - 6.1 6.3 12.7 0.17 11.5 4.9 2.2 2 0 0 2 2 2 0 Isy1-like splicing family Carb_anhydrase PF00194.21 KFP08430.1 - 3.4e-87 292.2 0.1 4.4e-87 291.8 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Pentaxin PF00354.17 KFP08430.1 - 1.4e-38 132.6 0.0 2.2e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.6 KFP08430.1 - 3e-11 43.7 2.2 4e-11 43.3 1.1 1.7 2 1 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily AhpC-TSA_2 PF13911.6 KFP08430.1 - 0.14 12.2 0.1 0.34 11.0 0.1 1.6 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Sugar_tr PF00083.24 KFP08431.1 - 5.3e-131 437.6 25.8 6.1e-131 437.4 25.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP08431.1 - 1.2e-20 73.8 50.9 2e-19 69.8 23.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 7tm_2 PF00002.24 KFP08432.1 - 1.9e-10 40.5 14.5 1.9e-10 40.5 14.5 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 KFP08432.1 - 3.4e-09 36.3 8.7 3.4e-09 36.3 8.7 2.0 1 1 1 2 2 2 1 Slime mold cyclic AMP receptor Frizzled PF01534.17 KFP08432.1 - 0.021 13.9 23.0 0.043 12.9 15.1 2.5 2 1 0 2 2 2 0 Frizzled/Smoothened family membrane region Stevor PF17410.2 KFP08432.1 - 3.2 7.2 3.7 1.2 8.7 1.2 1.5 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Glucosamine_iso PF01182.20 KFP08433.1 - 4e-60 203.5 0.0 6.2e-60 202.9 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase G6PD_C PF02781.16 KFP08433.1 - 1.7e-54 185.0 0.0 2.6e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KFP08433.1 - 8.8e-35 120.9 0.0 2.7e-34 119.3 0.0 1.9 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF5617 PF18493.1 KFP08433.1 - 0.046 13.8 1.1 0.093 12.8 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5617) SPRY PF00622.28 KFP08434.1 - 2.6e-19 69.5 0.0 3.7e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.16 KFP08434.1 - 4.1e-11 43.1 2.9 7.4e-11 42.2 2.9 1.4 1 0 0 1 1 1 1 SOCS box RVT_1 PF00078.27 KFP08435.1 - 0.00014 21.4 0.0 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2448 PF10476.9 KFP08436.1 - 5.4e-93 310.5 2.0 8.6e-93 309.9 2.0 1.3 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2448) Ima1_N PF09779.9 KFP08436.1 - 5e-33 114.8 13.4 5e-33 114.8 13.4 2.1 2 0 0 2 2 2 1 Ima1 N-terminal domain zf-RRPl_C4 PF17026.5 KFP08436.1 - 0.26 11.4 13.3 0.12 12.5 10.3 2.1 2 1 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Mito_carr PF00153.27 KFP08437.1 - 1.2e-60 201.5 1.5 3.8e-20 71.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Phospholip_A2_1 PF00068.19 KFP08438.1 - 2.2e-21 76.4 1.8 2.3e-21 76.3 1.8 1.0 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_1 PF00068.19 KFP08439.1 - 7.6e-28 97.2 12.0 8.2e-28 97.1 12.0 1.0 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_2 PF05826.12 KFP08439.1 - 0.0052 17.0 14.2 0.19 12.0 14.2 2.3 1 1 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.10 KFP08439.1 - 0.049 13.8 0.1 0.06 13.5 0.1 1.3 1 0 0 1 1 1 0 Parvovirus coat protein VP1 OTU PF02338.19 KFP08440.1 - 3.9e-10 40.3 0.0 1.1e-09 38.9 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease UBA_4 PF14555.6 KFP08440.1 - 0.0036 17.1 0.2 0.0067 16.2 0.2 1.4 1 0 0 1 1 1 1 UBA-like domain Peptidase_C65 PF10275.9 KFP08440.1 - 0.012 15.1 4.1 0.2 11.1 0.0 2.9 2 1 1 3 3 3 0 Peptidase C65 Otubain DUF726 PF05277.12 KFP08441.1 - 1.6e-128 428.5 3.2 1.9e-128 428.2 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF900 PF05990.12 KFP08441.1 - 6e-05 22.7 0.0 9.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.15 KFP08441.1 - 0.002 17.4 0.0 0.0032 16.7 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase VirJ PF06057.11 KFP08441.1 - 0.0097 15.8 0.0 0.045 13.6 0.0 2.0 3 0 0 3 3 3 1 Bacterial virulence protein (VirJ) Palm_thioest PF02089.15 KFP08441.1 - 0.049 13.5 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Sm_multidrug_ex PF06695.11 KFP08441.1 - 0.12 13.1 4.2 0.44 11.2 4.2 2.1 1 1 0 1 1 1 0 Putative small multi-drug export protein 7tm_1 PF00001.21 KFP08442.1 - 5.8e-63 212.7 18.8 7.5e-63 212.3 18.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP08442.1 - 0.00023 21.0 10.1 0.00023 21.0 10.1 2.0 1 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP08442.1 - 0.0049 16.5 13.5 0.0096 15.6 13.5 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFP08442.1 - 0.005 16.2 20.5 0.0076 15.7 16.1 2.5 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF1385 PF07136.11 KFP08442.1 - 0.17 11.2 0.0 0.17 11.2 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1385) DAN PF03045.15 KFP08443.1 - 7.6e-24 83.9 7.4 1.1e-23 83.5 7.4 1.2 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.22 KFP08443.1 - 1e-06 29.0 6.3 1.4e-06 28.5 6.3 1.2 1 0 0 1 1 1 1 Cystine-knot domain DUF543 PF04418.12 KFP08444.1 - 9.3e-25 86.4 0.7 1e-24 86.3 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) DUF4956 PF16316.5 KFP08444.1 - 0.41 10.3 1.7 0.3 10.8 0.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4956) F_actin_cap_B PF01115.17 KFP08445.1 - 2.4e-110 367.8 0.0 2.8e-110 367.6 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.17 KFP08445.1 - 0.045 13.2 0.0 0.5 9.7 0.0 2.6 1 1 0 1 1 1 0 F-actin capping protein alpha subunit PQ-loop PF04193.14 KFP08446.1 - 4.4e-18 64.8 7.1 6.6e-11 41.8 2.2 2.6 2 0 0 2 2 2 2 PQ loop repeat Aldo_ket_red PF00248.21 KFP08447.1 - 1.4e-43 149.2 0.0 1.6e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RL10P_insert PF17777.1 KFP08448.1 - 5.6e-28 96.7 0.0 8.7e-28 96.1 0.0 1.2 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KFP08448.1 - 2.8e-15 56.3 0.1 3.9e-15 55.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 TraF PF13728.6 KFP08448.1 - 0.093 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein EMC1_C PF07774.13 KFP08449.1 - 4.8e-73 245.4 0.1 1.4e-72 243.8 0.1 1.8 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KFP08449.1 - 2e-10 40.7 1.9 5e-06 26.3 0.3 3.9 4 1 0 4 4 4 2 PQQ-like domain PQQ PF01011.21 KFP08449.1 - 1.2e-05 25.0 0.0 0.43 10.6 0.0 3.8 4 0 0 4 4 4 2 PQQ enzyme repeat Filament PF00038.21 KFP08450.1 - 6.1e-20 72.0 17.4 1.3e-10 41.4 1.4 2.1 2 0 0 2 2 2 2 Intermediate filament protein Snapin_Pallidin PF14712.6 KFP08450.1 - 0.0034 17.8 1.8 0.0034 17.8 1.8 2.0 2 0 0 2 2 2 1 Snapin/Pallidin HIN PF02760.15 KFP08450.1 - 0.026 14.2 0.1 0.048 13.4 0.1 1.3 1 0 0 1 1 1 0 HIN-200/IF120x domain Prefoldin PF02996.17 KFP08450.1 - 0.11 12.4 4.9 6.2 6.8 0.2 2.7 2 0 0 2 2 2 0 Prefoldin subunit CdvA PF18822.1 KFP08450.1 - 0.13 12.1 8.1 0.28 11.0 4.1 2.5 2 0 0 2 2 2 0 CdvA-like coiled-coil domain TLE_N PF03920.15 KFP08450.1 - 0.93 9.6 5.6 0.23 11.5 0.3 2.5 2 1 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain DUF724 PF05266.14 KFP08450.1 - 1 9.2 10.7 9.2 6.0 5.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF724) FlaC_arch PF05377.11 KFP08450.1 - 1.5 9.3 5.5 5.2 7.5 2.2 3.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Rnk_N PF14760.6 KFP08450.1 - 4.6 7.8 7.7 43 4.7 3.3 3.2 3 0 0 3 3 3 0 Rnk N-terminus Aldedh PF00171.22 KFP08451.1 - 3.6e-97 325.8 0.0 4.2e-97 325.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PAX PF00292.18 KFP08452.1 - 2e-75 250.6 0.9 3.2e-75 250.0 0.9 1.3 1 0 0 1 1 1 1 'Paired box' domain Homeodomain PF00046.29 KFP08452.1 - 1.3e-23 82.6 7.0 2.8e-23 81.5 7.0 1.6 1 0 0 1 1 1 1 Homeodomain Pax7 PF12360.8 KFP08452.1 - 8.2e-20 70.7 6.7 1.9e-19 69.6 6.7 1.6 1 0 0 1 1 1 1 Paired box protein 7 HTH_32 PF13565.6 KFP08452.1 - 3e-05 24.5 5.5 0.0021 18.6 0.0 3.4 2 1 1 3 3 3 2 Homeodomain-like domain Homeobox_KN PF05920.11 KFP08452.1 - 5.5e-05 23.0 1.6 9.9e-05 22.2 0.8 1.9 2 0 0 2 2 2 1 Homeobox KN domain HTH_23 PF13384.6 KFP08452.1 - 0.00011 21.9 2.2 0.0013 18.4 0.1 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_IS1 PF12759.7 KFP08452.1 - 0.15 11.7 0.0 0.38 10.4 0.0 1.6 1 0 0 1 1 1 0 InsA C-terminal domain Kelch_6 PF13964.6 KFP08453.1 - 5.2e-17 61.5 0.3 0.00073 19.7 0.0 4.4 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.25 KFP08453.1 - 3.3e-16 58.6 1.7 5.1e-06 26.0 0.0 4.0 3 1 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 KFP08453.1 - 3.2e-06 27.0 0.4 0.067 13.2 0.0 3.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP08453.1 - 6.1e-05 22.8 0.8 0.48 10.5 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 KFP08453.1 - 0.00066 19.9 0.3 0.054 13.8 0.0 3.4 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP08453.1 - 0.061 13.3 0.2 1.3 9.1 0.1 2.5 2 0 0 2 2 2 0 Kelch motif Ig_3 PF13927.6 KFP08454.1 - 1.1e-17 64.4 0.0 3.4e-06 27.5 0.0 4.0 4 0 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.6 KFP08454.1 - 3.6e-13 49.6 0.0 0.0047 17.2 0.0 4.6 4 1 0 4 4 4 3 Immunoglobulin domain I-set PF07679.16 KFP08454.1 - 2.8e-10 40.1 0.0 0.0002 21.3 0.0 3.4 4 0 0 4 4 4 2 Immunoglobulin I-set domain V-set PF07686.17 KFP08454.1 - 4.5e-09 36.5 0.0 4.2e-08 33.3 0.0 2.6 4 0 0 4 4 4 1 Immunoglobulin V-set domain ig PF00047.25 KFP08454.1 - 3.1e-07 30.5 0.0 0.043 14.0 0.0 3.6 4 0 0 4 4 4 2 Immunoglobulin domain C2-set_2 PF08205.12 KFP08454.1 - 2.6e-06 27.4 0.0 0.029 14.4 0.0 3.0 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain RhoGEF PF00621.20 KFP08455.1 - 5.5e-40 137.5 0.6 1.1e-39 136.5 0.6 1.6 1 0 0 1 1 1 1 RhoGEF domain IQ_SEC7_PH PF16453.5 KFP08455.1 - 0.011 15.7 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 PH domain Cytochrom_D1 PF02239.16 KFP08455.1 - 0.15 10.6 0.0 0.26 9.8 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain RCC1 PF00415.18 KFP08456.1 - 4.2e-59 197.0 5.4 1.1e-15 58.0 0.0 7.0 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFP08456.1 - 5e-35 118.6 12.3 8.9e-09 34.9 0.0 7.4 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat PAD PF03068.15 KFP08457.1 - 3.7e-168 559.5 0.0 4.4e-168 559.3 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) PAD_M PF08527.10 KFP08457.1 - 4.3e-65 218.2 0.0 6.2e-65 217.7 0.0 1.2 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) middle domain PAD_N PF08526.10 KFP08457.1 - 6.2e-36 123.2 0.0 1e-35 122.5 0.0 1.4 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) N-terminal domain PAD PF03068.15 KFP08458.1 - 7.4e-167 555.2 0.0 9e-167 554.9 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) PAD_M PF08527.10 KFP08458.1 - 1e-61 207.2 0.0 1.5e-61 206.7 0.0 1.3 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) middle domain PAD_N PF08526.10 KFP08458.1 - 7.9e-21 74.5 0.2 1.7e-20 73.5 0.2 1.6 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) N-terminal domain PAD PF03068.15 KFP08459.1 - 9.6e-158 525.2 0.0 1.2e-157 525.0 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) PAD_M PF08527.10 KFP08459.1 - 2.1e-61 206.2 0.0 3.3e-61 205.6 0.0 1.3 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) middle domain PAD_N PF08526.10 KFP08459.1 - 5.3e-29 100.9 0.0 8.6e-29 100.2 0.0 1.4 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) N-terminal domain BpuJI_N PF11564.8 KFP08459.1 - 0.16 11.2 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease BpuJI - N terminal Fer2_3 PF13085.6 KFP08460.1 - 2e-32 111.5 0.1 4e-32 110.5 0.1 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KFP08460.1 - 1.5e-09 38.2 4.9 1.5e-09 38.2 4.9 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KFP08460.1 - 9.8e-09 35.5 21.7 4.4e-07 30.3 8.3 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KFP08460.1 - 7.8e-07 29.1 2.6 7.8e-07 29.1 2.6 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KFP08460.1 - 0.0081 16.3 5.9 0.0081 16.3 5.9 2.6 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 KFP08460.1 - 0.01 15.8 3.4 0.014 15.4 0.3 2.3 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 KFP08460.1 - 0.026 15.1 7.0 0.026 15.1 7.0 3.0 2 2 0 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 KFP08460.1 - 0.12 12.6 0.2 0.12 12.6 0.2 2.5 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 KFP08460.1 - 0.17 12.9 9.3 1.6 9.7 1.3 3.1 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain Fer4_22 PF17179.4 KFP08460.1 - 0.21 12.5 6.4 1 10.2 3.4 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain E1-E2_ATPase PF00122.20 KFP08461.1 - 1.5e-36 125.6 0.0 3.1e-36 124.6 0.0 1.5 1 1 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 KFP08461.1 - 0.0001 21.9 0.1 0.00028 20.5 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus MARVEL PF01284.23 KFP08461.1 - 0.033 14.2 0.7 0.033 14.2 0.7 2.3 2 1 1 3 3 3 0 Membrane-associating domain LptF_LptG PF03739.14 KFP08461.1 - 0.07 12.0 1.3 0.11 11.3 1.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Hydrolase PF00702.26 KFP08461.1 - 0.21 11.8 0.0 0.3 11.3 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Rootletin PF15035.6 KFP08462.1 - 4.1e-22 79.1 18.6 4.1e-22 79.1 18.6 2.8 2 1 1 3 3 3 1 Ciliary rootlet component, centrosome cohesion DAP_B PF07930.12 KFP08462.1 - 0.11 12.4 1.9 0.14 12.1 1.5 1.4 1 1 0 1 1 1 0 D-aminopeptidase, domain B Fib_alpha PF08702.10 KFP08462.1 - 0.13 12.5 14.9 0.033 14.4 10.4 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CDT1_C PF16679.5 KFP08462.1 - 0.41 11.1 0.2 0.41 11.1 0.2 2.5 2 1 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain DUF3323 PF11796.8 KFP08462.1 - 0.99 9.3 11.6 1.2 9.0 11.6 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) DUF2951 PF11166.8 KFP08462.1 - 4.4 7.6 7.2 0.72 10.1 1.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2951) DUF1681 PF07933.14 KFP08463.1 - 8.4e-45 152.1 0.0 1e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) SUZ PF12752.7 KFP08464.1 - 6.4e-13 49.2 0.1 6.4e-13 49.2 0.1 2.6 3 0 0 3 3 3 1 SUZ domain SUZ-C PF12901.7 KFP08464.1 - 6.4e-09 35.7 4.3 1.2e-08 34.8 4.3 1.5 1 0 0 1 1 1 1 SUZ-C motif Kelch_4 PF13418.6 KFP08465.1 - 6.8e-29 99.6 0.4 6.6e-08 32.4 0.1 5.5 4 1 1 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP08465.1 - 2.1e-25 88.4 10.7 1.9e-08 34.4 0.1 6.2 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP08465.1 - 2.1e-23 81.8 5.5 6.4e-08 32.4 0.0 5.6 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KFP08465.1 - 1.8e-20 72.0 7.4 1.9e-08 33.9 0.3 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 KFP08465.1 - 2.9e-19 68.4 0.2 5.5e-06 25.9 0.0 5.5 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 KFP08465.1 - 2.9e-19 68.6 7.4 0.00038 20.6 0.1 5.3 4 1 1 5 5 5 4 Kelch motif F-box-like PF12937.7 KFP08465.1 - 2.2e-09 37.0 0.3 5.5e-09 35.8 0.1 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFP08465.1 - 3.5e-07 29.9 0.0 6.2e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 KFP08465.1 - 7.9e-06 25.4 0.0 1.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 F-box Pkinase_Tyr PF07714.17 KFP08466.1 - 3e-98 328.2 0.0 3.6e-98 328.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP08466.1 - 2.2e-49 168.2 0.0 2.8e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.6 KFP08466.1 - 2.9e-14 53.7 0.3 5.7e-14 52.8 0.3 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Haspin_kinase PF12330.8 KFP08466.1 - 0.00057 18.9 0.1 0.004 16.2 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KFP08466.1 - 0.097 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFP08466.1 - 0.14 11.7 0.5 2.3 7.8 0.1 2.6 2 1 0 3 3 3 0 RIO1 family Auxin_inducible PF02519.14 KFP08466.1 - 0.15 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Auxin responsive protein Pkinase_fungal PF17667.1 KFP08466.1 - 0.16 10.7 0.0 0.31 9.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase ABC1 PF03109.16 KFP08466.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 ABC1 family HSP20 PF00011.21 KFP08467.1 - 2.7e-16 59.5 0.0 4.7e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KFP08467.1 - 0.041 13.5 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 HSP20-like domain found in ArsA zf-H2C2_2 PF13465.6 KFP08468.1 - 4.2e-41 137.6 47.9 8.3e-08 32.3 1.2 7.4 8 0 0 8 8 7 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFP08468.1 - 2.8e-37 125.1 50.0 1.7e-06 28.1 1.0 7.1 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP08468.1 - 3.5e-30 102.1 45.3 0.00012 22.6 0.6 7.1 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFP08468.1 - 8.2e-25 86.2 26.3 2.9e-06 26.9 0.3 6.5 6 0 0 6 6 6 5 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFP08468.1 - 6.1e-18 64.6 16.6 0.00059 20.0 0.0 6.4 5 1 1 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP08468.1 - 6.7e-11 42.2 25.1 0.027 14.9 0.1 6.4 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-BED PF02892.15 KFP08468.1 - 7.3e-07 29.1 33.2 0.097 12.7 0.7 6.3 1 1 5 6 6 6 4 BED zinc finger zf-H2C2_5 PF13909.6 KFP08468.1 - 1.4e-06 27.9 59.6 0.048 13.4 4.9 9.4 7 4 0 7 7 7 4 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFP08468.1 - 1.3e-05 25.0 43.5 0.22 11.6 2.2 6.8 7 0 0 7 7 6 4 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFP08468.1 - 1.4e-05 24.8 24.7 0.56 10.2 0.2 6.8 7 0 0 7 7 6 2 zinc-finger of a C2HC-type zf-C2HE PF16278.5 KFP08468.1 - 2.3e-05 24.7 33.7 0.0059 17.0 0.7 6.1 1 1 5 6 6 6 2 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 KFP08468.1 - 6.6e-05 22.9 28.3 0.21 11.7 2.6 4.8 3 2 2 5 5 4 4 Zinc ribbon domain zf-C2H2_2 PF12756.7 KFP08468.1 - 0.00014 22.1 27.5 1 9.7 0.4 5.9 1 1 5 6 6 6 3 C2H2 type zinc-finger (2 copies) zinc_ribbon_9 PF14369.6 KFP08468.1 - 0.00015 22.0 18.0 0.29 11.4 0.1 5.5 6 0 0 6 6 5 2 zinc-ribbon HypA PF01155.19 KFP08468.1 - 0.00024 21.1 16.6 0.09 12.8 2.9 4.1 1 1 2 3 3 3 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Di19 PF05605.12 KFP08468.1 - 0.00029 21.1 29.2 0.018 15.3 3.8 4.6 1 1 5 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_15 PF17032.5 KFP08468.1 - 0.00044 20.9 19.9 0.16 12.8 3.9 3.9 2 2 0 4 4 4 2 zinc-ribbon family zf-Dof PF02701.15 KFP08468.1 - 0.0009 19.3 18.3 0.94 9.7 2.1 4.6 1 1 4 5 5 4 2 Dof domain, zinc finger C1_1 PF00130.22 KFP08468.1 - 0.0011 18.8 26.3 0.67 9.9 4.4 5.3 1 1 5 6 6 6 1 Phorbol esters/diacylglycerol binding domain (C1 domain) XPA_N PF01286.18 KFP08468.1 - 0.0034 17.4 28.6 0.19 11.8 0.1 6.5 7 0 0 7 7 6 2 XPA protein N-terminal zf-RING_7 PF02591.15 KFP08468.1 - 0.005 17.0 13.0 1.4 9.2 0.2 5.3 5 0 0 5 5 5 1 C4-type zinc ribbon domain zf-C2H2_8 PF15909.5 KFP08468.1 - 0.018 15.3 17.2 0.077 13.3 3.7 3.7 1 1 2 3 3 3 0 C2H2-type zinc ribbon Elf1 PF05129.13 KFP08468.1 - 0.023 14.7 1.2 0.023 14.7 1.2 3.9 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like zf_UBZ PF18439.1 KFP08468.1 - 0.029 14.0 26.0 3 7.5 0.1 6.5 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger FYVE PF01363.21 KFP08468.1 - 0.13 12.5 28.8 1.1 9.4 3.7 4.1 2 1 1 3 3 3 0 FYVE zinc finger GAGA PF09237.11 KFP08468.1 - 0.13 12.1 18.9 1.3 8.9 0.0 5.1 1 1 5 6 6 6 0 GAGA factor DUF3268 PF11672.8 KFP08468.1 - 0.13 12.6 16.6 1.2 9.5 0.1 3.6 2 1 2 4 4 4 0 zinc-finger-containing domain DUF2256 PF10013.9 KFP08468.1 - 0.39 10.9 21.6 8.2 6.6 0.1 6.1 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-trcl PF13451.6 KFP08468.1 - 0.47 10.4 0.1 0.47 10.4 0.1 5.8 6 0 0 6 6 6 0 Probable zinc-ribbon domain zf-CHCC PF10276.9 KFP08468.1 - 0.49 10.5 23.5 1.1 9.3 0.2 5.8 6 0 0 6 6 6 0 Zinc-finger domain PyrI_C PF02748.15 KFP08468.1 - 0.57 10.1 26.3 2.2 8.3 0.1 5.8 4 2 2 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Desulfoferrod_N PF06397.12 KFP08468.1 - 0.75 9.5 0.1 0.75 9.5 0.1 5.2 6 0 0 6 6 6 0 Desulfoferrodoxin, N-terminal domain zf-ribbon_3 PF13248.6 KFP08468.1 - 0.96 9.0 0.0 0.96 9.0 0.0 5.6 6 0 0 6 6 6 0 zinc-ribbon domain T4_baseplate PF12322.8 KFP08468.1 - 1 8.8 5.8 2.3 7.6 0.1 2.9 2 1 1 3 3 3 0 T4 bacteriophage base plate protein Sprouty PF05210.13 KFP08468.1 - 1.8 9.0 17.9 6.5 7.2 3.5 4.3 2 2 1 3 3 3 0 Sprouty protein (Spry) ROS_MUCR PF05443.11 KFP08468.1 - 2 8.5 8.4 1.4 9.0 0.4 3.3 2 2 1 4 4 3 0 ROS/MUCR transcriptional regulator protein zf-C2H2_3rep PF18868.1 KFP08468.1 - 2.4 8.8 24.2 5.4 7.7 0.4 5.5 1 1 4 6 6 6 0 Zinc finger C2H2-type, 3 repeats BolA PF01722.18 KFP08468.1 - 2.6 8.4 6.5 4.6 7.6 0.1 3.3 2 1 2 4 4 4 0 BolA-like protein zf-C2H2_9 PF16293.5 KFP08468.1 - 2.6 7.9 8.5 1.9 8.4 0.2 4.0 4 1 1 5 5 4 0 C2H2 type zinc-finger (1 copy) Trm112p PF03966.16 KFP08468.1 - 4.1 8.1 8.1 6.9 7.3 4.7 2.9 2 1 0 2 2 1 0 Trm112p-like protein TerY_C PF15616.6 KFP08468.1 - 4.5 7.4 12.6 0.23 11.6 2.0 3.0 1 1 3 4 4 4 0 TerY-C metal binding domain Rep_fac-A_C PF08646.10 KFP08468.1 - 7.2 6.4 12.5 5.7 6.7 0.1 4.0 1 1 3 4 4 4 0 Replication factor-A C terminal domain Arc_trans_TRASH PF08394.10 KFP08468.1 - 8.1 6.9 16.9 4.2 7.8 0.7 5.2 5 1 0 5 5 5 0 Archaeal TRASH domain zf-LYAR PF08790.11 KFP08468.1 - 10 6.2 23.0 8 6.5 0.0 5.9 6 0 0 6 6 5 0 LYAR-type C2HC zinc finger SPOC PF07744.13 KFP08469.1 - 1.2e-24 86.9 0.1 1.4e-24 86.8 0.1 1.0 1 0 0 1 1 1 1 SPOC domain RRM_1 PF00076.22 KFP08471.1 - 3.7e-27 93.9 1.1 1.9e-13 50.0 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP08471.1 - 1.2e-06 28.1 0.5 0.023 14.3 0.0 3.1 1 1 2 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KFP08471.1 - 0.00083 19.4 0.0 0.6 10.2 0.0 2.3 2 0 0 2 2 2 2 Limkain b1 RRM_occluded PF16842.5 KFP08471.1 - 0.012 15.5 0.0 0.11 12.4 0.0 2.3 2 1 1 3 3 3 0 Occluded RNA-recognition motif RRM_7 PF16367.5 KFP08471.1 - 0.026 14.6 0.1 13 6.0 0.0 3.3 3 1 0 3 3 3 0 RNA recognition motif TMEM82 PF15816.5 KFP08472.1 - 8.5e-59 199.0 6.4 4.1e-34 118.0 0.6 2.1 2 0 0 2 2 2 2 Transmembrane protein 82 Mito_carr PF00153.27 KFP08473.1 - 1.1e-50 169.5 2.4 6.4e-16 58.1 0.4 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein PH PF00169.29 KFP08474.1 - 2.4e-15 56.9 0.1 1.3e-12 48.2 0.0 2.8 2 0 0 2 2 2 2 PH domain RUN PF02759.19 KFP08474.1 - 3.4e-07 30.3 2.5 7.9e-07 29.1 1.5 2.2 2 0 0 2 2 2 1 RUN domain PH_9 PF15410.6 KFP08474.1 - 0.00014 22.2 0.0 0.14 12.6 0.0 2.9 3 0 0 3 3 3 2 Pleckstrin homology domain UBA PF00627.31 KFP08475.1 - 0.00019 21.3 0.1 0.00032 20.5 0.1 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Asp_protease PF09668.10 KFP08476.1 - 1.8e-39 134.3 1.1 2.3e-39 134.0 1.1 1.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFP08476.1 - 1.6e-17 63.8 0.0 5.1e-17 62.2 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KFP08476.1 - 0.0022 17.7 0.1 0.0022 17.7 0.1 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KFP08476.1 - 0.0066 17.1 0.0 0.019 15.6 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease DDOST_48kD PF03345.14 KFP08477.1 - 4.1e-142 473.9 0.0 4.6e-142 473.7 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta OmpH PF03938.14 KFP08478.1 - 0.025 14.9 8.1 0.025 14.9 8.1 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) ASPRs PF17641.2 KFP08478.1 - 0.036 14.3 2.5 0.048 13.9 2.5 1.1 1 0 0 1 1 1 0 Ancylostoma-associated secreted protein related HD_3 PF13023.6 KFP08478.1 - 0.06 13.3 3.5 0.052 13.5 2.7 1.3 1 1 0 1 1 1 0 HD domain Tautomerase_2 PF14552.6 KFP08478.1 - 0.43 10.7 2.8 4.7 7.4 0.5 2.3 2 0 0 2 2 2 0 Tautomerase enzyme TMPIT PF07851.13 KFP08478.1 - 0.5 9.6 4.3 0.59 9.3 4.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein BRE1 PF08647.11 KFP08478.1 - 0.51 10.4 14.6 0.074 13.1 5.3 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF745 PF05335.13 KFP08478.1 - 0.57 9.9 9.0 0.32 10.7 6.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF4407 PF14362.6 KFP08478.1 - 0.74 9.1 10.0 0.99 8.7 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CorA PF01544.18 KFP08478.1 - 0.87 8.8 5.2 1.1 8.5 5.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 KFP08478.1 - 1.7 7.3 4.5 2 7.1 4.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) AAA_23 PF13476.6 KFP08478.1 - 4.2 7.8 13.8 5.8 7.4 13.8 1.3 1 0 0 1 1 1 0 AAA domain PID PF00640.23 KFP08479.1 - 1e-05 25.6 0.0 1.2e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Linker_histone PF00538.19 KFP08480.1 - 2.3e-54 181.6 0.2 2.4e-18 66.2 0.0 3.4 3 0 0 3 3 3 3 linker histone H1 and H5 family SDA1 PF05285.12 KFP08480.1 - 3e-05 23.6 31.9 0.013 14.9 15.3 2.3 2 0 0 2 2 2 2 SDA1 YL1 PF05764.13 KFP08480.1 - 6.8e-05 23.1 17.7 6.8e-05 23.1 17.7 2.6 2 1 0 2 2 2 1 YL1 nuclear protein RRN3 PF05327.11 KFP08480.1 - 0.39 9.2 10.4 1 7.8 0.5 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 BSP_II PF05432.11 KFP08480.1 - 0.42 10.3 28.3 0.025 14.3 7.0 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Nop14 PF04147.12 KFP08480.1 - 1.1 7.3 32.7 0.43 8.7 11.7 2.1 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.14 KFP08480.1 - 2.6 6.2 33.8 0.13 10.6 14.8 2.3 2 0 0 2 2 2 0 CDC45-like protein Lin-8 PF03353.15 KFP08480.1 - 3.6 7.1 24.9 3.8 7.0 9.5 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist TEX19 PF15553.6 KFP08480.1 - 7.3 6.5 7.4 1.1 9.2 0.1 2.5 2 0 0 2 2 2 0 Testis-expressed protein 19 Alk_phosphatase PF00245.20 KFP08481.1 - 1.2e-101 340.7 0.0 1.4e-101 340.5 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase UCH PF00443.29 KFP08482.1 - 6.8e-33 114.2 0.3 6.8e-33 114.2 0.3 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP08482.1 - 1.8e-18 67.2 0.2 1.8e-18 67.2 0.2 3.8 4 1 1 5 5 5 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KFP08482.1 - 2.2e-10 41.0 0.2 1.4e-05 25.6 0.0 3.9 3 1 0 3 3 3 2 DUSP domain ubiquitin PF00240.23 KFP08482.1 - 4.1e-05 23.3 0.1 0.00013 21.6 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family Actin_micro PF17003.5 KFP08482.1 - 0.017 14.3 0.3 1.4 8.1 0.6 2.5 2 0 0 2 2 2 0 Putative actin-like family Laminin_G_1 PF00054.23 KFP08483.1 - 8.5e-17 61.6 0.0 9.9e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.24 KFP08483.1 - 2.5e-14 53.9 0.0 2.9e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Laminin G domain CDP-OH_P_transf PF01066.21 KFP08484.1 - 4.7e-10 40.1 1.1 4.7e-10 40.1 1.1 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF4267 PF14087.6 KFP08484.1 - 0.01 15.9 1.2 0.02 15.0 0.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4267) CCDC23 PF15674.5 KFP08485.1 - 5.5e-29 100.0 7.5 5.7e-29 99.9 7.5 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 23 zf-H2C2_2 PF13465.6 KFP08486.1 - 1.3e-23 82.3 28.3 3e-07 30.6 2.1 4.2 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFP08486.1 - 2.6e-17 62.2 34.2 3.3e-06 27.2 1.2 5.1 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP08486.1 - 2e-10 40.6 31.2 0.0078 17.0 1.0 4.9 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFP08486.1 - 0.0003 21.0 9.8 0.001 19.3 5.1 2.3 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-Di19 PF05605.12 KFP08486.1 - 0.00035 20.8 4.0 0.00035 20.8 4.0 3.4 2 1 2 4 4 3 2 Drought induced 19 protein (Di19), zinc-binding FOXP-CC PF16159.5 KFP08486.1 - 0.0026 18.4 8.8 0.11 13.2 0.9 3.1 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KFP08486.1 - 0.017 15.1 25.0 1.1 9.3 4.5 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2HE PF16278.5 KFP08486.1 - 0.024 15.1 12.8 0.3 11.6 3.2 2.9 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_10 PF18414.1 KFP08486.1 - 0.097 12.2 0.1 0.097 12.2 0.1 3.3 4 0 0 4 4 4 0 C2H2 type zinc-finger PyrI_C PF02748.15 KFP08486.1 - 0.29 11.1 0.1 0.29 11.1 0.1 3.6 3 1 1 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain FYDLN_acid PF09538.10 KFP08486.1 - 0.6 10.8 4.5 19 6.0 0.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-C2H2_9 PF16293.5 KFP08486.1 - 1.3 8.9 6.8 32 4.5 0.3 3.3 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) Zn-ribbon_8 PF09723.10 KFP08486.1 - 2.5 8.3 17.6 5.8 7.1 3.7 3.5 2 1 1 3 3 3 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 KFP08486.1 - 6.2 7.2 18.5 0.25 11.7 1.5 3.4 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KFP08486.1 - 7.2 7.0 13.8 5.8 7.3 1.3 3.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding PHC2_SAM_assoc PF16616.5 KFP08487.1 - 2.5e-50 170.3 1.7 3.5e-50 169.9 1.7 1.2 1 0 0 1 1 1 1 Unstructured region on Polyhomeotic-like protein 1 and 2 SAM_1 PF00536.30 KFP08487.1 - 4.1e-19 68.8 0.0 6.1e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP08487.1 - 1.1e-08 35.0 0.0 1.7e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFP08487.1 - 0.002 18.0 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain zf-CGNR PF11706.8 KFP08487.1 - 0.11 12.4 3.8 0.29 11.0 3.8 1.8 1 0 0 1 1 1 0 CGNR zinc finger Sugar_tr PF00083.24 KFP08489.1 - 5.9e-156 519.8 25.1 7.3e-156 519.5 25.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP08489.1 - 1.9e-19 69.8 33.6 1.3e-17 63.7 27.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2127 PF09900.9 KFP08489.1 - 0.31 11.3 5.1 0.077 13.2 0.8 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2127) Pox_EPC_I2-L1 PF12575.8 KFP08489.1 - 0.44 10.8 3.3 2.1 8.6 3.3 2.2 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 TPR_12 PF13424.6 KFP08490.1 - 1.2e-11 44.7 7.4 0.00069 19.9 0.3 3.7 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFP08490.1 - 0.0067 16.5 8.7 5.3 7.4 0.2 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFP08490.1 - 0.1 12.4 1.7 6 6.9 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFP08490.1 - 0.53 10.2 9.2 3.6 7.6 0.0 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat S-AdoMet_synt_C PF02773.16 KFP08491.1 - 1e-66 223.2 0.1 2.9e-66 221.7 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KFP08491.1 - 4.7e-41 139.8 0.0 8.6e-41 139.0 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KFP08491.1 - 1.7e-40 137.7 0.6 2.8e-40 137.0 0.1 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Phosphodiest PF01663.22 KFP08492.1 - 3.2e-11 43.4 0.6 7.9e-08 32.3 0.1 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KFP08492.1 - 0.052 12.9 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily TraB PF01963.17 KFP08493.1 - 1e-37 130.5 0.0 1.2e-37 130.3 0.0 1.0 1 0 0 1 1 1 1 TraB family RVT_1 PF00078.27 KFP08494.1 - 9.7e-23 80.8 0.0 1.6e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFP08494.1 - 1.9e-06 27.8 0.0 3.6e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase TraB PF01963.17 KFP08495.1 - 6.1e-24 85.3 0.0 6.7e-24 85.2 0.0 1.0 1 0 0 1 1 1 1 TraB family Lipase_GDSL_2 PF13472.6 KFP08496.1 - 0.0055 17.1 0.0 0.0098 16.3 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 KFP08496.1 - 0.0079 15.5 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 OSK domain MFS_1 PF07690.16 KFP08497.1 - 9.2e-24 84.0 23.2 1e-23 83.9 23.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KFP08497.1 - 0.00016 20.4 11.3 0.00044 18.9 11.2 1.8 1 1 1 2 2 2 1 MFS/sugar transport protein RAWUL PF16207.5 KFP08498.1 - 4.1e-16 59.4 0.8 1.1e-15 58.1 0.3 2.0 2 1 0 2 2 2 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 KFP08498.1 - 8.5e-12 44.7 8.1 2.1e-11 43.5 8.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP08498.1 - 4e-09 36.2 9.3 4e-09 36.2 9.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP08498.1 - 1e-07 32.1 8.0 1e-07 32.1 8.0 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFP08498.1 - 2.9e-06 27.1 8.4 2.9e-06 27.1 8.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP08498.1 - 2.5e-05 24.2 4.7 2.5e-05 24.2 4.7 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP08498.1 - 2.7e-05 24.0 9.5 2.7e-05 24.0 9.5 2.5 2 1 1 3 3 3 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFP08498.1 - 6.4e-05 23.2 4.9 6.4e-05 23.2 4.9 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KFP08498.1 - 0.00059 19.9 8.6 0.00059 19.9 8.6 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KFP08498.1 - 0.01 15.6 9.5 0.014 15.2 6.3 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 KFP08498.1 - 0.022 14.6 3.3 0.038 13.8 3.3 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KFP08498.1 - 0.029 14.2 9.8 0.029 14.2 9.8 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 GAGA PF09237.11 KFP08498.1 - 0.032 14.1 0.1 0.099 12.5 0.1 1.8 1 0 0 1 1 1 0 GAGA factor DUF3337 PF11816.8 KFP08498.1 - 0.033 14.1 5.5 1.1 9.1 5.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3337) zf-RING_10 PF16685.5 KFP08498.1 - 0.16 12.1 10.3 0.092 12.9 5.9 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 DZR PF12773.7 KFP08498.1 - 0.88 9.6 9.8 0.93 9.6 5.8 2.4 2 0 0 2 2 2 0 Double zinc ribbon DUF1272 PF06906.11 KFP08498.1 - 1.1 9.4 9.5 0.77 9.9 6.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Synaphin PF05835.12 KFP08499.1 - 1.1e-34 119.7 15.6 1.3e-34 119.6 15.6 1.0 1 0 0 1 1 1 1 Synaphin protein VIT1 PF01988.19 KFP08499.1 - 5.7 6.7 4.4 6.3 6.6 4.4 1.1 1 0 0 1 1 1 0 VIT family Epimerase_2 PF02350.19 KFP08500.1 - 1.8e-67 227.6 0.1 2.8e-67 227.0 0.1 1.2 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase ROK PF00480.20 KFP08500.1 - 1.1e-54 186.0 2.4 1.8e-54 185.2 2.4 1.4 1 0 0 1 1 1 1 ROK family Hexokinase_1 PF00349.21 KFP08500.1 - 0.00038 20.4 0.0 0.00076 19.4 0.0 1.4 1 0 0 1 1 1 1 Hexokinase DRTGG PF07085.12 KFP08500.1 - 0.0016 18.2 0.2 0.0051 16.6 0.2 1.9 1 0 0 1 1 1 1 DRTGG domain BcrAD_BadFG PF01869.20 KFP08500.1 - 0.0028 17.2 1.4 1.3 8.4 0.0 2.4 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family FGGY_N PF00370.21 KFP08500.1 - 0.0072 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DNA_primase_S PF01896.19 KFP08500.1 - 0.15 12.1 0.0 3.8 7.5 0.0 2.4 2 0 0 2 2 2 0 DNA primase small subunit Glucokinase PF02685.16 KFP08500.1 - 0.16 10.9 2.5 0.24 10.3 0.0 2.4 3 0 0 3 3 3 0 Glucokinase Clathrin_lg_ch PF01086.17 KFP08501.1 - 2.1e-48 165.4 9.5 2.8e-48 165.0 9.5 1.1 1 0 0 1 1 1 1 Clathrin light chain CENP-Q PF13094.6 KFP08501.1 - 8.3e-06 26.1 2.6 9.7e-06 25.9 2.6 1.1 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Myc-LZ PF02344.15 KFP08501.1 - 0.0023 18.0 1.4 0.0054 16.8 1.4 1.7 1 0 0 1 1 1 1 Myc leucine zipper domain ORC3_N PF07034.11 KFP08501.1 - 0.029 13.5 2.3 0.037 13.1 2.3 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus TBCA PF02970.16 KFP08501.1 - 0.66 10.4 9.2 5.8 7.3 9.2 2.3 1 1 1 2 2 2 0 Tubulin binding cofactor A NeuB PF03102.14 KFP08502.1 - 2.6e-78 262.8 0.0 3.1e-78 262.5 0.0 1.1 1 0 0 1 1 1 1 NeuB family SAF PF08666.12 KFP08502.1 - 2.3e-06 28.1 0.2 4.5e-06 27.2 0.2 1.5 1 0 0 1 1 1 1 SAF domain ChapFlgA PF13144.6 KFP08502.1 - 0.0071 16.4 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Chaperone for flagella basal body P-ring formation Opiods_neuropep PF01160.18 KFP08502.1 - 0.6 10.2 0.0 0.6 10.2 0.0 2.9 3 0 0 3 3 3 0 Vertebrate endogenous opioids neuropeptide zf-RING_11 PF17123.5 KFP08503.1 - 4.2e-08 32.8 6.0 9.5e-08 31.7 6.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KFP08503.1 - 5.7e-08 33.0 4.3 5.7e-08 33.0 4.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KFP08503.1 - 6.9e-05 22.6 3.5 0.00013 21.8 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP08503.1 - 9.8e-05 22.1 4.5 0.00021 21.1 4.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFP08503.1 - 0.00034 20.8 3.9 0.00034 20.8 3.9 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFP08503.1 - 0.0086 16.0 3.1 0.019 14.9 3.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFP08503.1 - 0.011 15.8 2.7 0.03 14.3 2.7 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KFP08503.1 - 0.13 11.9 4.0 0.25 11.0 4.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KFP08503.1 - 0.24 11.6 2.9 0.53 10.5 2.9 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KFP08503.1 - 3.4 7.8 8.3 0.089 12.8 1.3 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger SH2 PF00017.24 KFP08504.1 - 6.8e-18 64.5 0.1 1e-17 64.0 0.1 1.3 1 0 0 1 1 1 1 SH2 domain Ank_2 PF12796.7 KFP08505.1 - 2.5e-49 165.8 10.4 2.8e-19 69.5 0.8 5.5 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP08505.1 - 1.6e-38 126.3 9.6 1.2e-05 25.3 0.1 10.4 9 1 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.6 KFP08505.1 - 3.3e-38 129.6 4.8 7.4e-11 42.4 0.1 6.9 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 KFP08505.1 - 7.2e-36 121.1 16.0 1.6e-05 25.1 0.0 9.1 8 1 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.6 KFP08505.1 - 1e-33 114.9 7.8 6.6e-08 32.7 0.2 7.1 4 1 3 7 7 7 5 Ankyrin repeats (many copies) TPR_12 PF13424.6 KFP08505.1 - 3.6e-05 24.0 0.0 0.12 12.7 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFP08505.1 - 0.03 14.4 0.8 0.47 10.7 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFP08505.1 - 0.043 13.7 0.2 0.45 10.4 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Cnd1 PF12717.7 KFP08505.1 - 0.098 12.7 0.2 1.5 8.8 0.0 2.8 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Baculo_PEP_C PF04513.12 KFP08506.1 - 0.056 13.5 0.7 0.11 12.5 0.7 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 KFP08506.1 - 0.061 13.8 1.2 0.16 12.5 1.2 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Prenyltrans PF00432.21 KFP08507.1 - 3.1e-32 110.0 12.8 4.5e-10 39.1 0.0 7.6 7 1 0 7 7 7 6 Prenyltransferase and squalene oxidase repeat zf-RING_UBOX PF13445.6 KFP08508.1 - 2.7e-08 33.7 2.9 2.7e-08 33.7 2.9 3.0 3 0 0 3 3 3 1 RING-type zinc-finger zf-B_box PF00643.24 KFP08508.1 - 2.1e-06 27.8 7.7 2.1e-06 27.8 7.7 4.3 4 1 0 4 4 4 2 B-box zinc finger zf-C3HC4 PF00097.25 KFP08508.1 - 7.6e-06 25.7 4.4 7.6e-06 25.7 4.4 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) fn3 PF00041.21 KFP08508.1 - 3.2e-05 24.2 0.0 6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain zf-C3HC4_4 PF15227.6 KFP08508.1 - 3.2e-05 24.0 4.9 3.2e-05 24.0 4.9 3.5 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KFP08508.1 - 0.00039 20.2 4.1 0.00039 20.2 4.1 4.8 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP08508.1 - 0.0016 18.4 2.9 0.0016 18.4 2.9 4.3 3 1 0 3 3 3 1 zinc-RING finger domain SPRY PF00622.28 KFP08508.1 - 0.08 13.1 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 SPRY domain Phasin PF05597.11 KFP08508.1 - 0.11 12.5 1.2 0.3 11.1 1.2 1.7 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) CaMBD PF02888.16 KFP08510.1 - 7.5e-39 131.8 12.3 1.8e-38 130.6 10.7 2.2 2 0 0 2 2 2 1 Calmodulin binding domain SK_channel PF03530.14 KFP08510.1 - 4.7e-30 103.9 0.7 4.7e-30 103.9 0.7 2.6 2 0 0 2 2 2 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.16 KFP08510.1 - 8.9e-14 51.2 3.2 3.1e-13 49.5 3.2 1.9 1 0 0 1 1 1 1 Ion channel Med9 PF07544.13 KFP08510.1 - 0.0036 17.4 2.2 0.0038 17.3 0.6 1.8 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 IRK PF01007.20 KFP08510.1 - 0.18 11.6 5.0 0.17 11.7 2.4 2.2 2 1 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain SlyX PF04102.12 KFP08510.1 - 0.41 11.3 3.8 0.41 11.3 0.1 2.5 2 0 0 2 2 2 0 SlyX Prefoldin_2 PF01920.20 KFP08510.1 - 1.4 8.9 11.8 14 5.7 6.6 3.3 1 1 2 3 3 3 0 Prefoldin subunit YTH PF04146.15 KFP08511.1 - 2.3e-45 154.5 3.0 4.8e-44 150.2 3.0 2.7 1 1 0 1 1 1 1 YT521-B-like domain HA2 PF04408.23 KFP08511.1 - 3.2e-18 66.0 0.0 3.2e-18 66.0 0.0 2.4 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFP08511.1 - 1.1e-14 54.7 0.1 2.9e-14 53.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KFP08511.1 - 1.5e-11 44.5 0.0 3.8e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KFP08511.1 - 5.8e-10 39.2 0.2 1.1e-09 38.3 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ank_2 PF12796.7 KFP08511.1 - 7.7e-06 26.4 0.0 4.9e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) AAA_19 PF13245.6 KFP08511.1 - 3.7e-05 24.1 0.1 0.00012 22.5 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFP08511.1 - 0.0016 18.7 0.3 0.0077 16.5 0.3 2.2 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 KFP08511.1 - 0.0017 17.8 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 KaiC PhoH PF02562.16 KFP08511.1 - 0.0046 16.4 0.0 0.0092 15.4 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_23 PF13476.6 KFP08511.1 - 0.0059 17.1 0.5 0.054 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFP08511.1 - 0.0065 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Ank_4 PF13637.6 KFP08511.1 - 0.015 15.9 0.0 1.4 9.6 0.0 2.6 1 1 1 2 2 2 0 Ankyrin repeats (many copies) AAA_7 PF12775.7 KFP08511.1 - 0.022 14.3 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Ank_5 PF13857.6 KFP08511.1 - 0.061 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) SRP54 PF00448.22 KFP08511.1 - 0.068 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain T2SSE PF00437.20 KFP08511.1 - 0.074 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 KFP08511.1 - 0.075 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1651 PF07864.11 KFP08511.1 - 0.31 11.4 1.4 1.9 8.9 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1651) MCC-bdg_PDZ PF10506.9 KFP08512.1 - 2.9e-43 145.7 21.4 6.5e-28 96.5 7.3 7.5 6 2 3 9 9 9 2 PDZ domain of MCC-2 bdg protein for Usher syndrome Mod_r PF07200.13 KFP08512.1 - 0.00031 20.9 0.5 0.00031 20.9 0.5 6.5 4 1 1 5 5 5 2 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.11 KFP08512.1 - 0.00054 18.9 3.8 0.00054 18.9 3.8 5.8 4 1 2 6 6 6 2 Spc7 kinetochore protein ERM PF00769.19 KFP08512.1 - 0.0032 17.3 13.2 0.0032 17.3 13.2 4.8 3 2 1 4 4 4 2 Ezrin/radixin/moesin family FAM76 PF16046.5 KFP08512.1 - 0.005 16.2 5.1 0.005 16.2 5.1 5.0 2 2 3 5 5 5 1 FAM76 protein ATG16 PF08614.11 KFP08512.1 - 0.0065 16.7 5.4 0.0065 16.7 5.4 6.4 4 1 1 5 5 5 2 Autophagy protein 16 (ATG16) APG6_N PF17675.1 KFP08512.1 - 0.016 15.7 4.6 0.016 15.7 4.6 7.9 3 2 3 6 6 6 0 Apg6 coiled-coil region DUF1359 PF07097.11 KFP08512.1 - 2.7 8.3 6.9 14 6.0 0.0 4.2 4 1 0 4 4 4 0 Protein of unknown function (DUF1359) GAS PF13851.6 KFP08512.1 - 4.3 6.6 78.6 0.052 12.9 0.9 7.2 7 1 0 7 7 7 0 Growth-arrest specific micro-tubule binding DCP2 PF05026.13 KFP08513.1 - 5.7e-23 81.0 0.1 2e-21 76.1 0.2 2.6 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.28 KFP08513.1 - 1.2e-15 57.7 0.0 2.1e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain TB2_DP1_HVA22 PF03134.19 KFP08514.1 - 5.4e-28 96.7 1.9 6.3e-28 96.5 1.9 1.1 1 0 0 1 1 1 1 TB2/DP1, HVA22 family SRP19 PF01922.17 KFP08515.1 - 7.5e-26 90.9 0.0 9.4e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 SRP19 protein Arm_APC_u3 PF16629.5 KFP08516.1 - 3.1e-162 539.1 18.5 3.1e-162 539.1 18.5 3.8 4 0 0 4 4 3 1 Armadillo-associated region on APC APC_basic PF05956.11 KFP08516.1 - 1.8e-99 333.5 73.1 1.8e-99 333.5 73.1 9.0 8 3 0 10 10 3 1 APC basic domain EB1_binding PF05937.11 KFP08516.1 - 5.5e-93 310.4 23.3 5.5e-93 310.4 23.3 7.8 7 4 2 9 9 3 1 EB-1 Binding Domain APC_r PF05923.12 KFP08516.1 - 9.8e-72 235.5 45.2 1.6e-11 43.6 1.7 8.9 8 0 0 8 8 8 7 APC repeat APC_u5 PF16630.5 KFP08516.1 - 4.4e-51 172.1 6.4 4.4e-51 172.1 6.4 5.1 4 1 1 5 5 2 1 Unstructured region on APC between 1st and 2nd catenin-bdg motifs APC_u9 PF16633.5 KFP08516.1 - 6.7e-40 136.1 9.9 6.7e-40 136.1 9.9 4.8 4 0 0 4 4 1 1 Unstructured region on APC between 1st two creatine-rich regions APC_u14 PF16635.5 KFP08516.1 - 7.9e-40 135.3 11.2 7.9e-40 135.3 11.2 5.0 5 0 0 5 5 2 1 Unstructured region on APC between SAMP and APC_crr APC_rep PF18797.1 KFP08516.1 - 1.3e-36 125.4 1.0 1.3e-36 125.4 1.0 4.8 5 0 0 5 5 2 1 Adenomatous polyposis coli (APC) repeat APC_u15 PF16636.5 KFP08516.1 - 4.3e-29 100.8 8.2 4.3e-29 100.8 8.2 7.9 8 1 1 9 9 4 1 Unstructured region on APC between APC_crr regions 5 and 6 APC_N_CC PF16689.5 KFP08516.1 - 1.8e-28 98.4 7.3 1.8e-28 98.4 7.3 4.2 5 0 0 5 5 4 1 Coiled-coil N-terminus of APC, dimerisation domain Arm PF00514.23 KFP08516.1 - 1.1e-27 95.2 14.1 9.1e-07 28.7 0.4 6.9 6 0 0 6 6 6 5 Armadillo/beta-catenin-like repeat APC_u13 PF16634.5 KFP08516.1 - 2e-27 94.8 2.2 2e-27 94.8 2.2 3.3 3 0 0 3 3 3 1 Unstructured region on APC between APC_crr and SAMP APC_15aa PF05972.11 KFP08516.1 - 2.5e-22 77.7 26.5 1.9e-05 24.6 0.3 5.7 6 0 0 6 6 5 4 APC 15 residue motif Suppressor_APC PF11414.8 KFP08516.1 - 2e-21 75.8 4.5 2e-21 75.8 4.5 3.3 3 0 0 3 3 2 1 Adenomatous polyposis coli tumour suppressor protein SAMP PF05924.11 KFP08516.1 - 1.1e-19 69.1 20.0 8.4e-08 31.3 2.3 4.2 4 0 0 4 4 4 3 SAMP Motif JIP_LZII PF16471.5 KFP08516.1 - 0.065 13.4 10.8 0.068 13.3 3.3 3.5 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Sec7_N PF12783.7 KFP08516.1 - 0.15 12.0 0.1 0.41 10.5 0.1 1.7 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3361 PF11841.8 KFP08516.1 - 2.7 7.9 4.0 12 5.8 1.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3361) FERM_M PF00373.18 KFP08517.1 - 4.9e-20 72.1 1.5 6.6e-20 71.7 0.1 1.9 2 0 0 2 2 2 1 FERM central domain FERM_C PF09380.10 KFP08517.1 - 1.3e-17 63.9 0.9 2.6e-17 63.0 0.9 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KFP08517.1 - 4.7e-15 55.3 0.0 1.7e-14 53.5 0.0 2.0 2 0 0 2 2 2 1 FERM N-terminal domain FA PF08736.11 KFP08517.1 - 2.2e-14 53.2 2.1 2.2e-14 53.2 2.1 3.2 3 0 0 3 3 3 1 FERM adjacent (FA) Alveol-reg_P311 PF11092.8 KFP08518.1 - 1.8e-32 111.3 0.0 2e-32 111.1 0.0 1.0 1 0 0 1 1 1 1 Neuronal protein 3.1 (p311) START PF01852.19 KFP08519.1 - 6.6e-18 64.9 0.0 7.4e-18 64.7 0.0 1.0 1 0 0 1 1 1 1 START domain Pkinase PF00069.25 KFP08520.1 - 1.7e-46 158.7 0.0 1.9e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP08520.1 - 2.5e-15 56.5 0.0 2.8e-15 56.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP08520.1 - 0.00028 20.3 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Utp21 PF04192.12 KFP08521.1 - 4.7e-65 219.4 0.0 8.1e-65 218.6 0.0 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 KFP08521.1 - 2.7e-22 78.6 7.5 5.4e-09 36.5 0.1 8.9 10 0 0 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP08521.1 - 1.6e-11 44.3 0.4 0.0043 17.3 0.0 7.3 4 3 5 9 9 9 3 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KFP08521.1 - 0.00049 20.4 0.4 0.00096 19.4 0.4 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Cytochrom_D1 PF02239.16 KFP08521.1 - 0.015 13.9 0.0 0.027 13.0 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain SGL PF08450.12 KFP08521.1 - 0.12 11.9 0.0 0.67 9.5 0.0 2.2 3 0 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region Mito_carr PF00153.27 KFP08522.1 - 3.9e-19 68.4 0.1 1.1e-10 41.2 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein Glyco_hydro_38N PF01074.22 KFP08523.1 - 5.1e-106 354.3 4.6 8.1e-106 353.6 4.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KFP08523.1 - 1.4e-41 142.9 0.0 3.2e-41 141.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KFP08523.1 - 5.3e-26 90.6 0.0 1e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_57 PF03065.15 KFP08523.1 - 0.0013 18.0 0.1 0.0027 17.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 WAC_Acf1_DNA_bd PF10537.9 KFP08523.1 - 0.092 13.3 0.2 0.33 11.5 0.2 1.9 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal zf-RING_2 PF13639.6 KFP08525.1 - 1.8e-11 44.1 12.7 4.1e-11 43.0 12.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFP08525.1 - 1.1e-06 28.4 8.4 2.3e-06 27.4 8.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP08525.1 - 2.7e-06 27.1 12.1 5.9e-06 26.0 12.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFP08525.1 - 5.2e-06 26.1 5.7 1.2e-05 24.9 5.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KFP08525.1 - 6.4e-06 26.4 9.2 6.4e-06 26.4 9.2 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KFP08525.1 - 3e-05 23.8 9.3 5.5e-05 22.9 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP08525.1 - 0.0001 22.2 9.2 0.00025 21.0 9.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP08525.1 - 0.00012 22.0 10.2 0.00025 21.0 10.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KFP08525.1 - 0.00035 20.6 5.3 0.0007 19.6 5.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KFP08525.1 - 0.0096 15.8 7.2 0.0096 15.8 7.2 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 RINGv PF12906.7 KFP08525.1 - 0.92 9.7 7.1 2.2 8.5 7.1 1.7 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KFP08525.1 - 1.4 9.1 8.9 6.4 7.0 8.9 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KFP08525.1 - 2.4 8.0 6.2 3.5 7.5 4.9 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KFP08525.1 - 2.6 8.4 7.0 7.7 6.9 7.0 1.9 1 0 0 1 1 1 0 RING-like domain Pkinase_Tyr PF07714.17 KFP08526.1 - 5.4e-102 340.5 0.1 2.2e-101 338.5 0.0 2.1 2 1 1 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.25 KFP08526.1 - 2.8e-50 171.1 0.0 1.2e-49 169.1 0.0 2.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFP08526.1 - 1.1e-21 76.7 0.0 4e-21 74.9 0.0 2.1 1 0 0 1 1 1 1 SH2 domain FCH PF00611.23 KFP08526.1 - 1.8e-11 44.1 2.4 1.8e-11 44.1 2.4 3.1 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain LRR_6 PF13516.6 KFP08528.1 - 1.2e-13 49.9 6.6 0.14 12.3 0.0 10.0 11 0 0 11 11 11 3 Leucine Rich repeat LRR_4 PF12799.7 KFP08528.1 - 6.7e-07 29.5 6.6 0.5 10.9 2.2 6.1 3 2 3 7 7 7 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KFP08528.1 - 2.9e-06 27.1 3.1 7e-06 25.8 3.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFP08528.1 - 0.0019 18.0 4.6 0.0034 17.2 2.6 2.6 2 1 0 2 2 2 1 F-box domain LRR_1 PF00560.33 KFP08528.1 - 4.5 8.2 10.3 63 4.7 0.0 6.2 6 1 0 6 6 6 0 Leucine Rich Repeat Ephrin PF00812.17 KFP08529.1 - 9.5e-33 113.1 0.1 1.2e-32 112.8 0.1 1.1 1 0 0 1 1 1 1 Ephrin Bromodomain PF00439.25 KFP08530.1 - 1.4e-10 41.1 0.9 2.6e-10 40.2 0.2 1.9 2 0 0 2 2 2 1 Bromodomain PWWP PF00855.17 KFP08530.1 - 3.9e-10 40.0 0.3 3.9e-10 40.0 0.3 3.7 3 1 0 3 3 3 1 PWWP domain zf-MYND PF01753.18 KFP08530.1 - 0.016 15.3 22.1 0.016 15.3 22.1 4.0 3 1 0 3 3 3 0 MYND finger AMP-binding PF00501.28 KFP08531.1 - 4.4e-97 325.3 0.0 7.3e-74 248.9 0.0 2.6 2 1 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.11 KFP08531.1 - 8.3e-06 26.6 0.2 1.5e-05 25.8 0.2 1.4 1 0 0 1 1 1 1 DMAP1-binding Domain La PF05383.17 KFP08532.1 - 3.7e-14 52.5 0.2 7.9e-14 51.4 0.2 1.6 1 0 0 1 1 1 1 La domain NOG1_N PF17835.1 KFP08533.1 - 3.2e-51 173.5 1.7 3.2e-51 173.5 1.7 2.6 2 1 0 2 2 1 1 NOG1 N-terminal helical domain NOG1 PF06858.14 KFP08533.1 - 1.9e-28 98.0 0.1 4.5e-28 96.8 0.1 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 KFP08533.1 - 1.2e-23 82.8 8.1 9.5e-23 79.9 6.1 2.7 2 0 0 2 2 2 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 KFP08533.1 - 5.5e-20 71.6 0.0 1.6e-19 70.1 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFP08533.1 - 2.1e-11 43.6 0.0 4.7e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.22 KFP08533.1 - 2.3e-05 24.1 0.0 7.4e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 Ras family AIG1 PF04548.16 KFP08533.1 - 0.00012 21.4 0.4 0.0012 18.2 0.0 2.7 3 0 0 3 3 3 1 AIG1 family Roc PF08477.13 KFP08533.1 - 0.00059 20.0 0.1 0.021 15.0 0.0 3.1 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KFP08533.1 - 0.00069 19.6 0.1 0.43 10.5 0.0 3.0 2 1 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KFP08533.1 - 0.0016 18.5 7.0 0.19 11.8 0.0 3.5 2 2 1 3 3 2 2 Dynamin family SRPRB PF09439.10 KFP08533.1 - 0.002 17.6 0.6 0.05 13.0 0.0 3.1 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KFP08533.1 - 0.045 14.1 0.0 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Sigma70_r4_2 PF08281.12 KFP08533.1 - 0.063 13.0 0.0 0.22 11.2 0.0 2.0 1 0 0 1 1 1 0 Sigma-70, region 4 Lip_prot_lig_C PF10437.9 KFP08533.1 - 0.092 12.7 0.1 0.32 11.0 0.1 1.9 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus AvrPto PF11592.8 KFP08533.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Central core of the bacterial effector protein AvrPto G-alpha PF00503.20 KFP08533.1 - 0.26 10.4 5.7 0.38 9.9 0.1 3.3 3 1 1 4 4 4 0 G-protein alpha subunit DUF4484 PF14831.6 KFP08533.1 - 0.64 10.0 6.2 0.64 10.0 4.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4484) NUDIX PF00293.28 KFP08534.1 - 5.5e-25 87.9 0.0 7.3e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain WD40 PF00400.32 KFP08535.1 - 1.2e-26 92.5 23.4 5.2e-07 30.3 0.4 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.8 KFP08535.1 - 0.008 14.9 5.1 2.6 6.6 0.1 3.3 2 1 1 3 3 3 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KFP08535.1 - 0.019 15.3 3.2 3.5 8.0 0.1 4.2 4 2 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1640 PF07798.11 KFP08535.1 - 0.071 13.2 2.7 0.12 12.4 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) FAM76 PF16046.5 KFP08535.1 - 0.87 8.9 5.8 1.4 8.2 5.8 1.2 1 0 0 1 1 1 0 FAM76 protein A_deamin PF02137.18 KFP08536.1 - 5e-109 364.7 0.0 7.4e-109 364.2 0.0 1.3 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.26 KFP08536.1 - 1.4e-24 86.6 0.1 4e-11 43.5 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KFP08536.1 - 0.059 13.6 1.0 3.2 8.1 0.0 3.0 2 1 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 PFK PF00365.20 KFP08537.1 - 4.7e-206 682.4 9.2 3.1e-111 371.3 2.1 2.1 2 0 0 2 2 2 2 Phosphofructokinase M16C_assoc PF08367.11 KFP08538.1 - 1.7e-86 289.5 0.0 2.6e-86 288.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KFP08538.1 - 3.3e-29 102.2 0.0 3.7e-22 79.2 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KFP08538.1 - 8.4e-10 38.8 0.2 2.2e-05 24.5 0.0 3.7 4 0 0 4 4 4 2 Insulinase (Peptidase family M16) KMP11 PF03037.16 KFP08538.1 - 9.8 7.1 12.3 0.74 10.6 3.0 3.1 3 0 0 3 3 3 0 Kinetoplastid membrane protein 11 zf-C2H2 PF00096.26 KFP08539.1 - 9.2e-14 51.0 31.7 7.9e-05 22.9 8.9 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP08539.1 - 3.1e-10 40.0 13.7 1.8e-06 28.1 6.5 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP08539.1 - 1.8e-06 28.3 28.4 0.0091 16.8 7.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger DUF3850 PF12961.7 KFP08539.1 - 0.076 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) DUF4692 PF15763.5 KFP08539.1 - 0.9 10.0 6.2 0.76 10.2 4.8 1.5 1 1 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) zf-C2H2_8 PF15909.5 KFP08539.1 - 1.7 9.0 12.6 0.37 11.1 6.7 2.7 2 1 1 3 3 3 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 KFP08539.1 - 1.7 9.3 9.3 1.3 9.7 0.8 2.8 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 KFP08539.1 - 2.9 8.3 9.1 8.1 6.9 1.7 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding RVT_1 PF00078.27 KFP08540.1 - 0.14 11.7 0.0 0.35 10.3 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Frizzled PF01534.17 KFP08541.1 - 7.2e-79 265.2 6.3 7.6e-57 192.8 2.5 2.1 1 1 1 2 2 2 2 Frizzled/Smoothened family membrane region Fz PF01392.22 KFP08541.1 - 2.6e-34 118.2 2.7 4.3e-34 117.5 2.7 1.4 1 0 0 1 1 1 1 Fz domain Dicty_CAR PF05462.11 KFP08541.1 - 0.0039 16.4 2.7 0.007 15.5 2.7 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 KFP08541.1 - 0.077 12.3 0.8 0.13 11.5 0.8 1.5 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Cyclin_N PF00134.23 KFP08542.1 - 9.8e-15 54.4 0.1 1.7e-14 53.7 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KFP08542.1 - 1.1e-11 45.4 0.1 1.4e-11 45.0 0.1 1.3 1 0 0 1 1 1 1 Cyclin bZIP_1 PF00170.21 KFP08543.1 - 8.5e-21 73.8 11.6 1.4e-20 73.1 11.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor pKID PF02173.17 KFP08543.1 - 6.9e-20 70.2 2.3 1.7e-19 69.0 2.3 1.7 1 0 0 1 1 1 1 pKID domain bZIP_2 PF07716.15 KFP08543.1 - 2.1e-07 30.9 11.0 3.5e-07 30.2 11.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFP08543.1 - 0.0024 18.4 6.2 0.0044 17.5 6.2 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor MMgT PF10270.9 KFP08543.1 - 0.093 13.1 0.0 1.5 9.2 0.0 2.2 2 0 0 2 2 2 0 Membrane magnesium transporter IMCp PF12314.8 KFP08543.1 - 0.31 11.3 1.9 0.61 10.4 0.1 2.0 2 0 0 2 2 2 0 Inner membrane complex protein Cullin PF00888.22 KFP08544.1 - 1e-175 585.9 24.2 1.3e-175 585.6 24.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KFP08544.1 - 1.3e-26 92.4 4.7 1.3e-26 92.4 4.7 3.2 3 0 0 3 3 3 1 Cullin protein neddylation domain Rio2_N PF09202.11 KFP08544.1 - 0.0042 17.3 0.9 0.024 14.8 0.1 2.6 2 0 0 2 2 2 1 Rio2, N-terminal MukF_M PF17192.4 KFP08544.1 - 0.54 10.0 5.8 15 5.2 0.1 3.5 2 1 0 3 3 3 0 MukF middle domain PDZ PF00595.24 KFP08545.1 - 3.6e-37 126.6 4.8 2.4e-15 56.6 0.1 3.6 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 KFP08545.1 - 5.8e-19 67.7 0.0 5.8e-07 29.3 0.1 3.7 3 0 0 3 3 3 3 PDZ domain Par3_HAL_N_term PF12053.8 KFP08545.1 - 1.2e-15 57.5 1.7 5.3e-15 55.4 1.7 2.3 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins PDZ_2 PF13180.6 KFP08545.1 - 8.1e-15 54.9 0.5 5.2e-06 26.7 0.1 3.8 3 1 0 3 3 3 3 PDZ domain Yae1_N PF09811.9 KFP08548.1 - 2.2e-07 30.4 23.7 0.0021 17.7 11.8 3.1 2 1 0 2 2 2 2 Essential protein Yae1, N terminal CUB PF00431.20 KFP08549.1 - 2.9e-59 198.2 0.0 1.7e-29 102.3 0.0 2.7 2 0 0 2 2 2 2 CUB domain F5_F8_type_C PF00754.25 KFP08549.1 - 2.5e-53 179.5 1.3 1.1e-27 96.7 0.0 2.6 2 0 0 2 2 2 2 F5/8 type C domain DUF3481 PF11980.8 KFP08549.1 - 1e-47 159.7 0.3 1.9e-47 158.8 0.3 1.5 1 0 0 1 1 1 1 C-terminal domain of neuropilin glycoprotein MAM PF00629.23 KFP08549.1 - 1.3e-39 135.7 1.1 2.4e-39 134.9 1.1 1.4 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Integrin_beta PF00362.18 KFP08550.1 - 2.9e-116 387.4 0.1 3.9e-116 387.0 0.1 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_B_tail PF07965.12 KFP08550.1 - 1.4e-21 76.8 7.7 1.4e-21 76.8 7.7 4.3 5 0 0 5 5 5 1 Integrin beta tail domain I-EGF_1 PF18372.1 KFP08550.1 - 1.5e-12 47.3 12.1 1.5e-12 47.3 12.1 7.1 9 0 0 9 9 9 3 Integrin beta epidermal growth factor like domain 1 PSI_integrin PF17205.3 KFP08550.1 - 1.9e-12 46.7 7.4 1.9e-12 46.7 7.4 4.5 3 1 0 3 3 3 1 Integrin plexin domain Integrin_b_cyt PF08725.11 KFP08550.1 - 5.2e-10 38.8 0.7 9.9e-10 38.0 0.7 1.4 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain EGF_2 PF07974.13 KFP08550.1 - 2.5e-08 34.1 59.7 6.4e-06 26.4 16.5 6.8 6 1 0 6 6 6 3 EGF-like domain E_Pc_C PF06752.12 KFP08551.1 - 6.7e-98 327.4 44.0 6.7e-98 327.4 44.0 2.5 2 1 0 2 2 2 1 Enhancer of Polycomb C-terminus EPL1 PF10513.9 KFP08551.1 - 4.5e-06 27.1 0.7 4.5e-06 27.1 0.7 3.7 5 0 0 5 5 5 1 Enhancer of polycomb-like CAF1A PF12253.8 KFP08551.1 - 0.12 12.5 0.8 0.44 10.7 0.1 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A PKK PF12474.8 KFP08551.1 - 3.9 7.6 21.2 0.084 13.0 4.1 3.0 3 0 0 3 3 3 0 Polo kinase kinase Kinesin PF00225.23 KFP08552.1 - 6.2e-111 370.5 2.5 6.2e-111 370.5 2.5 2.9 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KFP08552.1 - 4e-24 85.3 0.2 4e-24 85.3 0.2 3.5 4 1 0 4 4 4 1 Microtubule binding APG6_N PF17675.1 KFP08552.1 - 0.014 15.9 24.6 0.014 15.9 24.6 5.7 2 2 3 5 5 5 0 Apg6 coiled-coil region DUF4226 PF10774.9 KFP08552.1 - 0.028 14.7 1.3 0.028 14.7 1.3 5.5 3 1 2 5 5 5 0 Domain of unknown function (DUF4226) Cation_ATPase PF13246.6 KFP08552.1 - 4.3 7.5 7.4 4.9 7.3 0.5 3.9 3 1 0 3 3 3 0 Cation transport ATPase (P-type) DUF3584 PF12128.8 KFP08552.1 - 9.8 3.5 104.3 0.01 13.4 33.7 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) SH3-WW_linker PF16618.5 KFP08553.1 - 5.1e-68 229.5 11.0 5.1e-68 229.5 11.0 3.4 4 0 0 4 4 4 1 Linker region between SH3 and WW domains on ARHGAP12 RhoGAP PF00620.27 KFP08553.1 - 2.5e-50 170.3 1.0 4.1e-50 169.5 0.1 1.8 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 KFP08553.1 - 1.6e-09 38.2 0.4 8.9e-09 35.8 0.4 2.4 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.6 KFP08553.1 - 4.6e-08 32.8 0.2 1.1e-07 31.6 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH_9 PF15410.6 KFP08553.1 - 2e-07 31.4 0.2 6.7e-07 29.7 0.2 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_1 PF00018.28 KFP08553.1 - 6e-07 29.0 3.3 5.3e-06 25.9 0.9 2.7 2 0 0 2 2 2 1 SH3 domain WW PF00397.26 KFP08553.1 - 0.00027 21.0 24.7 0.00091 19.3 5.5 4.4 3 1 1 4 4 4 2 WW domain SH3_10 PF17902.1 KFP08553.1 - 0.021 14.9 0.4 0.087 12.9 0.1 2.2 2 0 0 2 2 2 0 SH3 domain SH3_3 PF08239.11 KFP08553.1 - 0.13 12.5 1.8 1.6 9.1 0.4 3.0 2 0 0 2 2 2 0 Bacterial SH3 domain Glyco_hyd_101C PF17451.2 KFP08553.1 - 1.7 8.9 14.6 0.75 10.1 0.7 4.0 5 0 0 5 5 5 0 Glycosyl hydrolase 101 beta sandwich domain zf-H2C2_2 PF13465.6 KFP08554.1 - 1.5e-30 104.2 54.5 6.2e-08 32.7 2.5 7.9 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFP08554.1 - 3.3e-24 83.9 66.3 0.0001 22.5 5.0 7.7 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP08554.1 - 2.2e-14 52.9 64.1 0.028 15.2 4.4 8.1 8 0 0 8 8 8 7 C2H2-type zinc finger zf-met PF12874.7 KFP08554.1 - 4.1e-09 36.5 46.1 0.015 15.6 1.2 6.8 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFP08554.1 - 1.1e-08 35.2 26.0 1.4e-07 31.6 1.3 3.9 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KFP08554.1 - 9.1e-08 32.2 54.6 0.0088 16.3 1.9 7.9 8 0 0 8 8 7 5 Zinc-finger double-stranded RNA-binding Homeodomain PF00046.29 KFP08554.1 - 3.4e-05 23.6 0.0 9.7e-05 22.1 0.0 1.8 1 0 0 1 1 1 1 Homeodomain zf-C2H2_6 PF13912.6 KFP08554.1 - 0.013 15.5 60.9 0.51 10.4 0.9 7.5 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2HE PF16278.5 KFP08554.1 - 0.079 13.4 0.1 0.079 13.4 0.1 6.9 3 2 2 5 5 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_9 PF16293.5 KFP08554.1 - 0.15 11.9 15.8 5 7.0 0.0 5.3 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) Evr1_Alr PF04777.13 KFP08554.1 - 0.46 11.0 0.0 0.46 11.0 0.0 5.7 3 2 1 5 5 5 0 Erv1 / Alr family zf-C2H2_2 PF12756.7 KFP08554.1 - 0.72 10.2 45.1 0.12 12.7 1.9 6.9 3 2 3 6 6 6 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 KFP08554.1 - 1.5 8.7 4.2 49 3.8 0.0 3.7 3 1 0 3 3 3 0 GAGA factor TRAF6_Z2 PF18048.1 KFP08554.1 - 3.6 7.8 15.4 32 4.7 0.5 5.4 6 0 0 6 6 6 0 TNF receptor-associated factor 6 zinc finger 2 zf-H2C2_2 PF13465.6 KFP08555.1 - 7.2e-08 32.5 29.9 0.00018 21.8 4.6 5.0 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP08555.1 - 4.4e-05 24.0 41.4 0.025 15.4 3.1 5.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP08555.1 - 0.061 13.8 43.1 0.042 14.3 4.1 4.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type Gelsolin PF00626.22 KFP08556.1 - 8.6e-20 70.4 0.3 3.9e-05 23.5 0.0 5.8 5 0 0 5 5 5 4 Gelsolin repeat VHP PF02209.19 KFP08556.1 - 6.2e-16 58.2 0.1 2e-15 56.6 0.1 2.0 1 0 0 1 1 1 1 Villin headpiece domain DUF4695 PF15766.5 KFP08556.1 - 3.6e-07 30.4 4.5 0.0066 16.7 0.0 4.2 2 1 1 3 3 3 2 Domain of unknown function (DUF4695) JCAD PF15351.6 KFP08557.1 - 0 1755.9 61.0 0 1755.7 61.0 1.0 1 0 0 1 1 1 1 Junctional protein associated with coronary artery disease RL PF17797.1 KFP08558.1 - 1e-33 115.1 0.1 2e-33 114.1 0.1 1.5 1 0 0 1 1 1 1 RL domain PAP_assoc PF03828.19 KFP08558.1 - 3.2e-06 27.2 0.1 1e-05 25.6 0.1 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase ELM2 PF01448.24 KFP08558.1 - 0.19 12.5 0.2 3.8 8.3 0.0 2.6 3 0 0 3 3 3 0 ELM2 domain Pkinase PF00069.25 KFP08559.1 - 7.7e-49 166.4 0.0 1.3e-48 165.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP08559.1 - 2.2e-25 89.4 0.0 4.9e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP08559.1 - 1.6e-05 23.9 0.0 2.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP08559.1 - 0.013 15.4 0.1 0.033 14.1 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KFP08559.1 - 0.045 13.1 0.0 6.6 5.9 0.0 2.2 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.22 KFP08559.1 - 0.085 12.5 0.1 0.24 11.0 0.1 1.7 1 1 1 2 2 2 0 RIO1 family RVT_1 PF00078.27 KFP08560.1 - 0.077 12.5 0.0 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) FA_desaturase PF00487.24 KFP08561.1 - 4.8e-15 56.1 7.9 4.8e-15 56.1 7.9 1.4 1 1 0 1 1 1 1 Fatty acid desaturase wnt PF00110.19 KFP08562.1 - 8.6e-97 324.4 21.5 1.1e-96 324.1 21.5 1.0 1 0 0 1 1 1 1 wnt family Sec16_C PF12931.7 KFP08563.1 - 1.7e-05 24.6 1.3 0.0001 22.1 1.3 2.2 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 WD40 PF00400.32 KFP08563.1 - 0.0026 18.5 7.2 0.096 13.6 0.0 4.3 4 1 0 4 4 4 2 WD domain, G-beta repeat Prp18 PF02840.15 KFP08563.1 - 0.047 13.7 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 Prp18 domain NDUF_B8 PF05821.11 KFP08564.1 - 5.9e-71 238.0 6.3 6.5e-71 237.9 6.3 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Cupin_8 PF13621.6 KFP08565.1 - 2e-40 139.1 0.3 2.5e-40 138.8 0.3 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KFP08565.1 - 2.1e-07 30.8 0.6 2.7e-07 30.4 0.1 1.5 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.22 KFP08565.1 - 0.029 14.8 0.2 0.14 12.6 0.2 2.1 1 1 0 1 1 1 0 JmjC domain, hydroxylase Cupin_2 PF07883.11 KFP08565.1 - 0.05 13.3 0.0 0.57 9.9 0.0 2.2 2 0 0 2 2 2 0 Cupin domain Pax2_C PF12403.8 KFP08567.1 - 6.2e-43 145.5 7.2 1.5e-42 144.2 7.2 1.7 1 0 0 1 1 1 1 Paired-box protein 2 C terminal Homeodomain PF00046.29 KFP08567.1 - 0.0066 16.3 0.1 0.013 15.4 0.1 1.4 1 0 0 1 1 1 1 Homeodomain CUE PF02845.16 KFP08568.1 - 0.033 13.9 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 CUE domain LRR_4 PF12799.7 KFP08569.1 - 1.1e-08 35.2 0.1 0.11 12.9 0.0 5.0 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFP08569.1 - 4.2e-08 32.6 5.4 8.5 6.7 0.1 6.5 6 0 0 6 6 6 2 Leucine Rich repeat F-box PF00646.33 KFP08569.1 - 2.7e-06 27.1 6.4 3.3e-05 23.6 0.6 2.9 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.7 KFP08569.1 - 0.039 13.9 1.9 0.039 13.9 1.9 2.3 2 0 0 2 2 2 0 F-box-like LRR_1 PF00560.33 KFP08569.1 - 0.48 11.2 11.7 13 6.8 0.1 6.3 6 2 0 6 6 6 0 Leucine Rich Repeat Ins_P5_2-kin PF06090.12 KFP08569.1 - 0.51 9.7 3.1 0.67 9.3 2.5 1.4 1 1 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase Transp_inhibit PF18791.1 KFP08569.1 - 2 8.0 4.0 33 4.1 0.0 4.3 5 1 1 6 6 6 0 Transport inhibitor response 1 protein domain Sec7 PF01369.20 KFP08570.1 - 1.3e-42 145.6 0.0 2.2e-42 144.8 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KFP08570.1 - 2.9e-37 127.6 0.0 8.3e-37 126.2 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KFP08570.1 - 1.2e-12 48.2 0.0 3.2e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 PH domain RHD_DNA_bind PF00554.22 KFP08571.1 - 2.3e-66 222.9 0.1 3.6e-66 222.3 0.1 1.3 1 0 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.5 KFP08571.1 - 1.2e-38 131.3 0.0 2.1e-38 130.5 0.0 1.4 1 0 0 1 1 1 1 Rel homology dimerisation domain Ank_2 PF12796.7 KFP08571.1 - 1.3e-29 102.6 4.5 1.9e-13 50.8 0.3 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP08571.1 - 3.3e-29 97.7 6.5 0.00048 20.4 0.1 6.7 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 KFP08571.1 - 1.3e-28 98.2 16.3 7.9e-05 22.9 0.1 6.7 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 KFP08571.1 - 2.1e-25 88.4 4.5 1.3e-06 28.5 0.1 5.0 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP08571.1 - 4e-25 87.8 3.9 2.1e-07 31.3 0.0 5.4 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Death PF00531.22 KFP08571.1 - 4.4e-06 26.7 0.6 1.5e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 Death domain Tim44 PF04280.15 KFP08571.1 - 0.014 15.5 0.4 0.049 13.7 0.2 1.9 2 0 0 2 2 2 0 Tim44-like domain Frag1 PF10277.9 KFP08572.1 - 5.4e-47 160.2 10.8 6e-47 160.0 10.8 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.13 KFP08572.1 - 2.7e-05 23.8 12.4 3.5e-05 23.5 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF998) DUF2768 PF10966.8 KFP08572.1 - 0.041 14.3 1.5 0.041 14.3 1.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2768) Homeodomain PF00046.29 KFP08574.1 - 9.1e-23 79.9 9.4 1.5e-22 79.2 9.4 1.3 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 KFP08574.1 - 2.2e-08 33.7 0.6 5.1e-08 32.5 0.6 1.6 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 KFP08574.1 - 0.0037 17.1 0.6 0.0037 17.1 0.6 2.6 3 0 0 3 3 3 1 Homeobox KN domain Auxin_canalis PF05703.11 KFP08574.1 - 6.5 6.6 10.8 0.81 9.6 5.9 1.7 2 0 0 2 2 2 0 Auxin canalisation ELO PF01151.18 KFP08575.1 - 7.9e-58 195.9 21.4 9e-58 195.7 21.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family UDPGT PF00201.18 KFP08576.1 - 2.1e-108 363.3 0.0 2.4e-108 363.1 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KFP08576.1 - 0.00045 20.2 0.0 0.00096 19.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain SRP40_C PF05022.12 KFP08577.1 - 1e-28 100.0 4.3 3.7e-28 98.2 4.3 2.1 1 0 0 1 1 1 1 SRP40, C-terminal domain DBB PF14545.6 KFP08578.1 - 1.5e-51 174.0 0.0 2.3e-51 173.3 0.0 1.3 1 0 0 1 1 1 1 Dof, BCAP, and BANK (DBB) motif, TIR_3 PF18567.1 KFP08578.1 - 7.6e-48 161.8 0.1 1.7e-47 160.7 0.1 1.6 1 0 0 1 1 1 1 Toll/interleukin-1 receptor domain EMP70 PF02990.16 KFP08579.1 - 1.4e-155 518.9 20.8 1.7e-155 518.6 20.8 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 EVC2_like PF12297.8 KFP08579.1 - 0.47 9.1 1.6 15 4.2 0.0 2.2 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein CUB PF00431.20 KFP08580.1 - 4.5e-188 612.8 6.4 1.7e-39 134.6 0.2 5.2 5 0 0 5 5 5 5 CUB domain Astacin PF01400.24 KFP08580.1 - 3.9e-73 245.1 0.0 7.6e-73 244.2 0.0 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) FXa_inhibition PF14670.6 KFP08580.1 - 6.1e-14 52.0 28.3 2.8e-08 33.9 10.8 4.1 4 0 0 4 4 3 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 KFP08580.1 - 1.2e-11 44.6 27.8 1e-06 28.8 8.6 2.8 2 0 0 2 2 2 2 Calcium-binding EGF domain cEGF PF12662.7 KFP08580.1 - 8.3e-11 41.6 6.3 3.1e-06 27.0 1.8 3.4 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF_3 PF12947.7 KFP08580.1 - 2e-07 31.1 18.5 0.00089 19.4 4.6 3.2 2 1 0 2 2 2 2 EGF domain CUB_2 PF02408.20 KFP08580.1 - 4.8e-06 26.3 0.6 0.85 9.4 0.0 5.1 5 0 0 5 5 5 2 CUB-like domain EGF PF00008.27 KFP08580.1 - 0.00039 20.7 29.0 0.0014 18.9 7.3 3.3 3 0 0 3 3 3 2 EGF-like domain Reprolysin_4 PF13583.6 KFP08580.1 - 0.00068 19.3 0.1 0.0013 18.5 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like hEGF PF12661.7 KFP08580.1 - 0.0019 18.8 18.6 0.088 13.5 4.0 3.0 2 0 0 2 2 2 2 Human growth factor-like EGF DUF3558 PF12079.8 KFP08580.1 - 0.012 15.6 5.4 6.8 6.7 0.0 4.1 3 1 0 4 4 4 0 Protein of unknown function (DUF3558) Peptidase_M10 PF00413.24 KFP08580.1 - 0.018 14.9 3.1 1 9.2 0.1 2.8 3 0 0 3 3 3 0 Matrixin p450 PF00067.22 KFP08581.1 - 3.5e-141 471.1 0.0 4e-141 470.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Njmu-R1 PF15053.6 KFP08581.1 - 0.013 14.6 0.1 0.041 13.0 0.0 1.7 2 0 0 2 2 2 0 Mjmu-R1-like protein family DUF4657 PF15552.6 KFP08582.1 - 1.9e-05 24.4 1.4 3.5e-05 23.5 1.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4657) G_path_suppress PF15991.5 KFP08582.1 - 0.036 14.2 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor ZapB PF06005.12 KFP08582.1 - 0.068 13.6 0.7 0.2 12.1 0.7 1.7 1 0 0 1 1 1 0 Cell division protein ZapB SNF2_N PF00176.23 KFP08583.1 - 1e-55 188.9 0.2 4.6e-55 186.7 0.2 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFP08583.1 - 2.3e-22 79.4 0.1 1.6e-21 76.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP08583.1 - 9.3e-07 29.0 0.0 8.2e-06 25.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Shugoshin_C PF07557.11 KFP08583.1 - 0.094 12.5 1.0 0.19 11.5 1.0 1.6 1 0 0 1 1 1 0 Shugoshin C terminus DUF4749 PF15936.5 KFP08584.1 - 1.1e-26 93.8 3.1 1.1e-26 93.8 3.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4749) PDZ PF00595.24 KFP08584.1 - 9e-13 48.4 0.1 2e-12 47.3 0.1 1.6 2 0 0 2 2 2 1 PDZ domain LIM PF00412.22 KFP08584.1 - 2e-11 43.9 5.6 3.8e-11 43.0 5.6 1.4 1 0 0 1 1 1 1 LIM domain PDZ_6 PF17820.1 KFP08584.1 - 3.5e-08 33.2 0.0 6.6e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP08584.1 - 0.0006 20.1 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain DZR PF12773.7 KFP08584.1 - 0.81 9.8 5.2 6.7 6.8 5.3 2.2 1 1 1 2 2 2 0 Double zinc ribbon SH3_9 PF14604.6 KFP08585.1 - 2.5e-39 132.9 0.5 1.6e-14 53.5 0.1 3.7 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 KFP08585.1 - 1.1e-38 130.6 0.4 9.3e-12 44.4 0.0 4.3 4 0 0 4 4 4 3 SH3 domain SH3_2 PF07653.17 KFP08585.1 - 8.2e-30 102.3 0.2 2.6e-12 46.2 0.0 3.6 4 0 0 4 4 4 3 Variant SH3 domain Sorb PF02208.16 KFP08585.1 - 3.7e-19 68.3 1.3 1e-18 66.9 1.3 1.9 1 0 0 1 1 1 1 Sorbin homologous domain MitMem_reg PF13012.6 KFP08586.1 - 8.5e-24 84.1 0.5 1.5e-23 83.4 0.2 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KFP08586.1 - 4.4e-16 58.9 0.6 7.5e-16 58.2 0.6 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Annexin PF00191.20 KFP08587.1 - 8.3e-102 333.3 8.8 1.8e-27 95.2 0.6 4.1 4 0 0 4 4 4 4 Annexin Metallophos PF00149.28 KFP08588.1 - 2.3e-36 126.2 0.0 3.6e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UCH PF00443.29 KFP08590.1 - 2.3e-21 76.4 0.1 6.7e-21 74.9 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP08590.1 - 4.5e-07 29.8 3.2 4.5e-07 29.8 3.2 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase EPO_TPO PF00758.18 KFP08590.1 - 0.025 14.6 0.3 0.058 13.4 0.3 1.5 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin Dscam_C PF12355.8 KFP08590.1 - 0.81 10.7 8.0 3.9 8.5 0.8 3.1 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal Calsarcin PF05556.11 KFP08591.1 - 2e-94 315.9 0.0 2.8e-94 315.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) PDZ PF00595.24 KFP08592.1 - 1.2e-11 44.8 0.0 2.9e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Calsarcin PF05556.11 KFP08592.1 - 1.7e-10 40.9 2.6 0.0026 17.4 0.1 3.9 2 1 1 4 4 4 3 Calcineurin-binding protein (Calsarcin) PDZ_6 PF17820.1 KFP08592.1 - 4.2e-06 26.5 0.0 8.5e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Sec23_trunk PF04811.15 KFP08593.1 - 1.4e-90 303.1 0.1 2e-90 302.7 0.1 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KFP08593.1 - 1.8e-26 91.9 0.0 4e-26 90.8 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KFP08593.1 - 3.9e-19 69.2 0.0 3.4e-18 66.2 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KFP08593.1 - 9e-14 51.2 11.5 2.2e-13 50.0 11.5 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KFP08593.1 - 1.8e-10 40.6 0.0 4.5e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat CHCH PF06747.13 KFP08594.1 - 3.9e-09 36.4 3.0 4.7e-09 36.1 3.0 1.1 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 KFP08594.1 - 0.0091 16.2 0.7 0.012 15.8 0.7 1.3 1 1 0 1 1 1 1 Mature-T-Cell Proliferation I type UCR_hinge PF02320.16 KFP08594.1 - 0.033 14.4 1.2 0.7 10.1 0.1 2.0 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein SWIM PF04434.17 KFP08595.1 - 0.0035 17.0 6.1 0.0075 15.9 6.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger HSNSD PF12062.8 KFP08597.1 - 5.2e-254 843.5 0.0 7.2e-254 843.0 0.0 1.2 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.27 KFP08597.1 - 4.4e-45 154.2 0.0 7.1e-45 153.6 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP08597.1 - 8.9e-09 36.0 0.5 0.0061 17.0 0.2 2.5 1 1 1 2 2 2 2 Sulfotransferase family Pkinase PF00069.25 KFP08598.1 - 1.4e-71 241.0 0.0 1.9e-71 240.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CaMKII_AD PF08332.10 KFP08598.1 - 6.2e-60 201.0 0.0 1e-59 200.3 0.0 1.3 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain Pkinase_Tyr PF07714.17 KFP08598.1 - 6.5e-32 110.8 0.0 1.3e-31 109.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase SnoaL_3 PF13474.6 KFP08598.1 - 5.2e-11 42.8 0.0 1e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KFP08598.1 - 5.8e-10 39.5 0.0 1.1e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Pkinase_fungal PF17667.1 KFP08598.1 - 0.00066 18.6 0.0 0.012 14.4 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KFP08598.1 - 0.0089 15.4 0.2 0.017 14.5 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SnoaL_2 PF12680.7 KFP08598.1 - 0.011 16.4 0.0 0.02 15.5 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain APH PF01636.23 KFP08598.1 - 0.014 15.4 0.1 3.8 7.4 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KFP08598.1 - 0.13 11.8 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Yae1_N PF09811.9 KFP08599.1 - 2.4e-25 87.9 104.2 0.0013 18.4 10.8 9.5 1 1 6 7 7 7 7 Essential protein Yae1, N terminal Trypsin PF00089.26 KFP08600.1 - 4.7e-67 226.0 0.8 6.1e-67 225.7 0.8 1.2 1 0 0 1 1 1 1 Trypsin Kringle PF00051.18 KFP08600.1 - 1.7e-16 60.3 4.4 3.5e-16 59.3 4.4 1.6 1 0 0 1 1 1 1 Kringle domain Trypsin_2 PF13365.6 KFP08600.1 - 1.3e-06 29.3 0.0 2.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFP08600.1 - 0.00036 20.9 0.0 0.0011 19.3 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) EGF PF00008.27 KFP08600.1 - 0.00093 19.4 8.4 0.00093 19.4 8.4 3.1 3 0 0 3 3 3 1 EGF-like domain hEGF PF12661.7 KFP08600.1 - 0.0035 17.9 2.4 0.0035 17.9 2.4 3.2 2 1 0 2 2 2 1 Human growth factor-like EGF EGF_2 PF07974.13 KFP08600.1 - 0.012 16.0 8.7 0.012 16.0 8.7 3.2 3 0 0 3 3 3 0 EGF-like domain DUF1505 PF07403.11 KFP08600.1 - 0.45 10.7 2.8 0.86 9.8 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1505) PfkB PF00294.24 KFP08601.1 - 1.6e-77 260.8 0.3 1.8e-77 260.6 0.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KFP08601.1 - 0.071 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Raf1_N PF18578.1 KFP08601.1 - 0.09 13.3 0.5 0.35 11.4 0.2 2.0 2 0 0 2 2 2 0 Rubisco accumulation factor 1 alpha helical domain DSPc PF00782.20 KFP08602.1 - 1.6e-32 112.1 0.0 3e-30 104.7 0.0 2.1 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP08602.1 - 0.0022 17.6 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KFP08602.1 - 0.0027 18.0 0.0 0.0065 16.8 0.0 1.5 1 1 0 1 1 1 1 Rit1 DUSP-like domain DSPn PF14671.6 KFP08602.1 - 0.0033 17.9 0.0 0.011 16.1 0.0 1.8 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half PTPlike_phytase PF14566.6 KFP08602.1 - 0.076 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate PAP2_C PF14360.6 KFP08603.1 - 1.5e-27 96.0 10.2 1.5e-27 96.0 10.2 3.0 3 1 0 3 3 3 1 PAP2 superfamily C-terminal SAM_1 PF00536.30 KFP08603.1 - 1.6e-11 44.5 0.1 3.6e-11 43.3 0.0 1.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP08603.1 - 3.7e-06 27.0 0.0 8e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PAP2 PF01569.21 KFP08603.1 - 0.0014 18.4 11.2 0.0014 18.4 11.2 1.9 1 1 0 1 1 1 1 PAP2 superfamily SAM_PNT PF02198.16 KFP08603.1 - 0.028 14.4 0.2 0.26 11.3 0.0 2.6 3 0 0 3 3 3 0 Sterile alpha motif (SAM)/Pointed domain PAP2_3 PF14378.6 KFP08603.1 - 0.099 12.3 17.3 0.016 14.9 12.7 1.8 1 1 1 2 2 2 0 PAP2 superfamily Porin_3 PF01459.22 KFP08604.1 - 4.2e-85 285.5 5.5 4.7e-85 285.3 5.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin Methyltransf_3 PF01596.17 KFP08605.1 - 8.8e-73 244.0 0.2 1.1e-72 243.7 0.2 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KFP08605.1 - 7.4e-15 55.9 0.0 1.3e-14 55.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP08605.1 - 9.3e-05 23.1 0.0 0.00018 22.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP08605.1 - 0.00012 21.9 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFP08605.1 - 0.00034 20.4 0.0 0.00066 19.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 KFP08605.1 - 0.0018 17.6 0.1 0.0032 16.8 0.1 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 KFP08605.1 - 0.0082 16.1 0.1 0.063 13.2 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain AFOR_N PF02730.15 KFP08605.1 - 0.082 12.8 0.1 0.19 11.6 0.0 1.5 2 0 0 2 2 2 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain CMAS PF02353.20 KFP08605.1 - 0.095 12.0 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase BK_channel_a PF03493.18 KFP08606.1 - 2.3e-33 114.3 0.1 5.1e-33 113.2 0.1 1.6 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 KFP08606.1 - 3.9e-18 65.6 19.1 7.7e-18 64.6 19.1 1.4 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFP08606.1 - 3.7e-14 52.5 2.9 3.7e-14 52.5 2.9 2.6 2 0 0 2 2 2 1 Ion channel TrkA_N PF02254.18 KFP08606.1 - 1.6e-05 25.1 0.1 0.00015 22.0 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain Lig_chan PF00060.26 KFP08606.1 - 0.14 12.0 3.1 0.89 9.4 0.7 2.5 2 0 0 2 2 2 0 Ligand-gated ion channel RNA_pol_Rpb1_1 PF04997.12 KFP08607.1 - 2.4e-95 319.5 1.6 4e-95 318.7 1.6 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KFP08607.1 - 1.1e-88 297.2 0.2 1.6e-88 296.6 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KFP08607.1 - 1.3e-74 250.0 0.1 2.3e-74 249.1 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KFP08607.1 - 5.2e-42 143.4 0.0 9.9e-41 139.3 0.0 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KFP08607.1 - 2.3e-32 111.1 0.0 8.1e-32 109.4 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Ribosomal_S24e PF01282.19 KFP08608.1 - 6.8e-46 154.1 0.4 1.3e-45 153.3 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e Ion_trans_2 PF07885.16 KFP08609.1 - 1.1e-11 44.6 1.0 5.1e-11 42.4 0.6 2.0 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 KFP08609.1 - 8.2e-10 38.6 0.0 1.8e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 KFP08609.1 - 9.1e-09 34.9 0.1 1.4e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 Ion transport protein DUF2959 PF11172.8 KFP08609.1 - 0.016 15.4 0.2 0.028 14.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) SlyX PF04102.12 KFP08609.1 - 0.026 15.2 1.3 0.084 13.5 1.3 1.8 1 0 0 1 1 1 0 SlyX LPP PF04728.13 KFP08609.1 - 0.049 14.0 1.5 0.15 12.5 1.5 1.9 1 0 0 1 1 1 0 Lipoprotein leucine-zipper DUF1664 PF07889.12 KFP08609.1 - 0.15 12.1 1.3 0.33 11.0 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KFP08609.1 - 0.53 10.3 5.0 0.43 10.6 1.9 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 KFP08609.1 - 2.5 8.6 6.0 0.37 11.3 1.5 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein EF-hand_7 PF13499.6 KFP08610.1 - 1.2e-11 44.9 5.9 2.6e-11 43.8 5.9 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP08610.1 - 3.4e-10 38.7 3.5 6.1e-05 22.3 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFP08610.1 - 2e-08 33.5 4.9 0.00011 21.8 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFP08610.1 - 8.6e-07 28.2 1.9 0.0075 15.7 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFP08610.1 - 2.3e-06 27.4 1.4 5.5e-06 26.1 1.4 1.7 1 0 0 1 1 1 1 EF-hand domain pair DUF5580 PF17743.1 KFP08610.1 - 0.00019 20.1 0.3 0.00027 19.6 0.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SPARC_Ca_bdg PF10591.9 KFP08610.1 - 0.007 16.7 1.1 0.014 15.7 1.1 1.4 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 KFP08610.1 - 0.027 15.3 0.2 0.054 14.4 0.2 1.4 1 0 0 1 1 1 0 EF-hand domain DUF1325 PF07039.11 KFP08610.1 - 0.095 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 SGF29 tudor-like domain Ras PF00071.22 KFP08611.1 - 3.1e-63 212.2 0.3 3.6e-63 212.0 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP08611.1 - 7.5e-36 123.0 0.1 1.5e-35 122.0 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP08611.1 - 1e-12 47.9 0.0 1.2e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFP08611.1 - 2.2e-05 24.0 0.0 2.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP08611.1 - 5.2e-05 23.3 0.0 8.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP08611.1 - 0.00039 20.4 0.3 0.36 10.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFP08611.1 - 0.0017 17.9 0.0 0.0052 16.4 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFP08611.1 - 0.013 15.9 0.1 0.026 14.9 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain MCR_beta PF02241.18 KFP08611.1 - 0.021 14.4 0.4 0.028 14.0 0.4 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain BrnT_toxin PF04365.13 KFP08611.1 - 0.062 13.7 0.1 0.46 10.8 0.0 2.1 2 0 0 2 2 2 0 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system PP2C PF00481.21 KFP08612.1 - 4.2e-29 102.0 0.0 4.9e-24 85.4 0.0 3.7 3 1 1 4 4 4 2 Protein phosphatase 2C CpXC PF14353.6 KFP08612.1 - 0.26 11.3 1.5 0.72 9.9 0.1 2.2 2 0 0 2 2 2 0 CpXC protein PCAF_N PF06466.11 KFP08613.1 - 1.8e-103 345.5 0.7 2.9e-103 344.8 0.7 1.3 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain PF00439.25 KFP08613.1 - 3.6e-25 87.8 0.4 8.5e-25 86.6 0.4 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KFP08613.1 - 3.9e-10 40.0 0.0 8.6e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFP08613.1 - 1.6e-07 31.3 0.0 3.3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFP08613.1 - 6.8e-06 26.4 0.2 1.4e-05 25.4 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFP08613.1 - 0.11 12.6 0.1 0.3 11.2 0.1 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-met PF12874.7 KFP08614.1 - 3.2e-21 75.0 16.9 3.1e-08 33.7 2.4 3.6 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP08614.1 - 8.9e-18 64.1 14.2 1.6e-06 28.2 3.2 3.3 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFP08614.1 - 1.3e-07 31.9 7.4 0.016 15.5 0.1 3.2 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.12 KFP08614.1 - 1.3e-06 28.1 6.6 0.059 13.1 0.0 3.3 3 0 0 3 3 3 2 U1 zinc finger AKAP95 PF04988.12 KFP08614.1 - 1.5e-06 28.6 8.2 0.15 12.3 0.6 3.1 3 0 0 3 3 3 3 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.6 KFP08614.1 - 0.0026 18.5 5.3 1.4 10.0 0.6 3.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP08614.1 - 0.0056 17.1 11.0 2 9.0 2.0 3.6 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 KFP08614.1 - 0.01 15.4 4.1 1.1 8.9 0.3 2.5 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_9 PF16293.5 KFP08614.1 - 0.027 14.3 5.3 4.2 7.3 0.3 3.5 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-Sec23_Sec24 PF04810.15 KFP08614.1 - 0.038 14.0 3.4 15 5.7 0.1 3.4 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger DUF3449 PF11931.8 KFP08614.1 - 0.047 13.5 5.2 1.3 8.8 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3449) zf-DBF PF07535.12 KFP08614.1 - 0.055 13.6 8.5 0.086 13.0 0.9 3.3 3 0 0 3 3 3 0 DBF zinc finger UPF0728 PF15092.6 KFP08614.1 - 0.059 13.2 0.1 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0728 S_2TMBeta PF18153.1 KFP08614.1 - 0.064 13.0 0.5 0.13 12.1 0.5 1.5 1 0 0 1 1 1 0 SMODS-associating 2TM, beta-strand rich effector domain DUF4187 PF13821.6 KFP08614.1 - 0.082 12.7 0.0 2.4 8.0 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4187) OrfB_Zn_ribbon PF07282.11 KFP08614.1 - 0.11 12.5 4.3 4 7.4 0.4 3.3 3 0 0 3 3 3 0 Putative transposase DNA-binding domain zinc_ribbon_15 PF17032.5 KFP08614.1 - 0.28 11.9 5.1 19 6.1 0.1 2.9 2 1 1 3 3 3 0 zinc-ribbon family Actin_micro PF17003.5 KFP08614.1 - 0.66 9.1 11.0 2 7.5 0.1 2.8 2 1 0 2 2 2 0 Putative actin-like family zf-BED PF02892.15 KFP08614.1 - 7 6.8 8.4 5.6 7.1 0.1 2.8 3 0 0 3 3 2 0 BED zinc finger PHD_2 PF13831.6 KFP08614.1 - 7.9 6.1 6.9 8.9 6.0 0.2 3.0 3 0 0 3 3 3 0 PHD-finger Yae1_N PF09811.9 KFP08615.1 - 1.7e-17 62.8 47.3 1.8e+04 -14.8 47.3 5.8 1 1 0 1 1 1 0 Essential protein Yae1, N terminal zf-met PF12874.7 KFP08616.1 - 1.4e-08 34.8 0.7 3.4e-08 33.6 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP08616.1 - 0.00025 21.2 0.7 0.00025 21.2 0.7 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding UQ_con PF00179.26 KFP08617.1 - 1.4e-43 147.9 0.0 1.5e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFP08617.1 - 0.00064 19.4 0.0 0.00079 19.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KFP08617.1 - 0.016 15.5 0.0 0.022 15.0 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 KFP08617.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 UEV domain UQ_con PF00179.26 KFP08618.1 - 2.1e-43 147.3 0.0 2.3e-43 147.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFP08618.1 - 0.0017 18.1 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KFP08618.1 - 0.0098 16.2 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KFP08618.1 - 0.095 12.6 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 UEV domain Ras PF00071.22 KFP08619.1 - 3.8e-26 91.6 0.3 4.4e-26 91.4 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP08619.1 - 2.7e-11 43.7 0.0 5.4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP08619.1 - 9.8e-09 34.9 0.3 1.3e-08 34.5 0.3 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP08619.1 - 5.2e-06 26.5 0.0 8.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP08619.1 - 0.0011 18.5 1.6 0.25 10.9 1.6 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFP08619.1 - 0.0018 18.2 0.6 0.12 12.3 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KFP08619.1 - 0.0082 16.2 0.3 0.14 12.2 0.3 2.7 1 1 0 1 1 1 1 Dynamin family cobW PF02492.19 KFP08619.1 - 0.043 13.4 2.5 2 8.0 0.3 2.1 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 KFP08619.1 - 0.071 13.1 0.1 0.28 11.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KFP08619.1 - 0.08 12.5 0.0 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_24 PF13479.6 KFP08619.1 - 0.098 12.4 0.1 0.13 12.0 0.1 1.3 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFP08619.1 - 0.2 12.0 0.8 1.2 9.4 0.1 2.2 1 1 0 2 2 2 0 AAA domain Ribosomal_L15e PF00827.17 KFP08620.1 - 4.7e-98 326.5 3.7 5.4e-98 326.3 3.7 1.0 1 0 0 1 1 1 1 Ribosomal L15 Hepatitis_core PF00906.20 KFP08620.1 - 2 7.9 7.6 0.14 11.7 0.3 2.0 2 0 0 2 2 2 0 Hepatitis core antigen zf-C4 PF00105.18 KFP08621.1 - 2.9e-31 107.7 15.9 7.2e-31 106.5 15.9 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFP08621.1 - 3.9e-25 88.7 0.3 1.1e-24 87.2 0.3 1.7 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor LpxD PF04613.14 KFP08621.1 - 0.037 13.8 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD zf-C4 PF00105.18 KFP08622.1 - 2.2e-30 104.9 15.9 4.1e-30 104.0 15.9 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFP08622.1 - 1.5e-16 60.6 0.0 5.7e-16 58.7 0.0 1.9 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor Class_IIIsignal PF04021.12 KFP08623.1 - 0.65 10.1 0.2 0.65 10.1 0.2 2.1 2 0 0 2 2 2 0 Class III signal peptide zf-C4 PF00105.18 KFP08624.1 - 3.8e-34 117.0 16.3 4.4e-34 116.8 16.3 1.0 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFP08625.1 - 1.1e-13 51.2 0.3 2.3e-13 50.2 0.0 1.6 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor PAW PF04721.17 KFP08626.1 - 2.7e-74 249.2 0.9 2.7e-74 249.2 0.9 1.7 2 0 0 2 2 2 1 PNGase C-terminal domain, mannose-binding module PAW PUB PF09409.10 KFP08626.1 - 1.9e-15 56.5 0.7 4.5e-15 55.3 0.0 2.0 2 0 0 2 2 2 1 PUB domain Transglut_core PF01841.19 KFP08626.1 - 8.9e-15 55.1 1.4 1.7e-14 54.2 0.5 2.0 2 0 0 2 2 2 1 Transglutaminase-like superfamily Rad4 PF03835.15 KFP08626.1 - 2.9e-10 40.0 0.8 5.9e-10 39.0 0.8 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain ketoacyl-synt PF00109.26 KFP08627.1 - 3.5e-55 187.3 4.9 4.6e-55 186.9 2.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KFP08627.1 - 1.5e-37 128.3 0.1 3e-37 127.2 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KFP08627.1 - 4.8e-06 26.1 0.1 6e-05 22.5 0.1 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KFP08627.1 - 0.066 13.7 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension LRR_8 PF13855.6 KFP08628.1 - 1.3e-17 63.3 4.0 1.8e-11 43.6 0.2 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRRNT PF01462.18 KFP08628.1 - 6.2e-09 35.3 3.0 6.2e-09 35.3 3.0 2.1 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.7 KFP08628.1 - 1.7e-08 34.6 9.5 2.2e-05 24.7 0.5 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP08628.1 - 1.1e-06 28.6 0.1 1.8e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFP08628.1 - 0.00037 20.7 10.1 0.073 13.7 0.5 4.4 4 2 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 KFP08628.1 - 0.00078 19.3 2.9 0.33 11.1 0.1 3.5 3 0 0 3 3 3 2 Leucine Rich repeat Pkinase PF00069.25 KFP08630.1 - 6.4e-30 104.4 0.8 6.4e-30 104.4 0.8 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP08630.1 - 5.8e-21 74.9 0.1 9.4e-21 74.3 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Arm PF00514.23 KFP08630.1 - 1.3e-05 25.0 9.6 0.00081 19.4 0.1 4.4 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat APH PF01636.23 KFP08630.1 - 0.00029 20.8 0.1 0.0022 18.0 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFP08630.1 - 0.00077 18.3 0.2 0.0019 17.0 0.2 1.7 1 1 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KFP08630.1 - 0.0017 18.0 0.1 0.0032 17.1 0.1 1.6 1 1 0 1 1 1 1 RIO1 family TraD PF06412.11 KFP08630.1 - 0.12 12.1 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Conjugal transfer protein TraD HCO3_cotransp PF00955.21 KFP08631.1 - 4.7e-245 814.2 7.9 5.8e-245 813.9 7.9 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 KFP08631.1 - 1.8e-107 359.1 0.0 3.3e-107 358.3 0.0 1.4 1 0 0 1 1 1 1 Band 3 cytoplasmic domain MFS_MOT1 PF16983.5 KFP08631.1 - 1.5 9.2 6.7 0.89 10.0 2.2 2.9 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily T-box_assoc PF16176.5 KFP08632.1 - 8.9e-110 366.1 2.7 1.2e-109 365.7 2.7 1.1 1 0 0 1 1 1 1 T-box transcription factor-associated T-box PF00907.22 KFP08632.1 - 1.7e-62 210.9 0.1 2.7e-62 210.3 0.1 1.3 1 0 0 1 1 1 1 T-box Yae1_N PF09811.9 KFP08633.1 - 4.6e-13 48.6 33.8 5.6e+02 0.3 33.8 4.4 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Cmc1 PF08583.10 KFP08634.1 - 3.4e-16 59.0 4.5 4.4e-16 58.6 4.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 KFP08634.1 - 0.0084 15.8 1.4 0.0084 15.8 1.4 2.0 1 1 1 2 2 2 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Colipase PF01114.18 KFP08634.1 - 0.014 15.1 0.9 0.023 14.4 0.9 1.3 1 0 0 1 1 1 0 Colipase, N-terminal domain COX17 PF05051.13 KFP08634.1 - 0.15 12.5 4.6 0.16 12.4 0.5 2.2 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.13 KFP08634.1 - 3.8 7.8 10.2 7.3 6.8 1.7 2.6 2 1 1 3 3 3 0 CHCH domain TBD PF12845.7 KFP08635.1 - 4.4e-19 68.1 1.4 5.5e-17 61.4 0.2 3.2 2 0 0 2 2 2 1 TBD domain Speriolin_N PF15058.6 KFP08635.1 - 0.22 11.6 2.9 0.36 10.9 2.1 1.8 1 1 0 1 1 1 0 Speriolin N terminus MAD PF05557.13 KFP08635.1 - 0.46 8.8 28.2 0.19 10.1 5.0 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein Arc_PepC PF06819.11 KFP08635.1 - 0.53 10.4 6.2 0.6 10.3 1.5 2.7 1 1 1 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain Fez1 PF06818.15 KFP08635.1 - 2.1 8.8 26.6 3.7 7.9 17.9 2.3 1 1 1 2 2 2 0 Fez1 OmpH PF03938.14 KFP08635.1 - 2.6 8.4 26.8 1.2 9.5 11.3 2.8 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) BRE1 PF08647.11 KFP08635.1 - 7.4 6.7 31.3 3.4 7.8 10.3 3.8 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase RRM_1 PF00076.22 KFP08636.1 - 2.5e-32 110.5 0.0 2e-16 59.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KFP08636.1 - 0.017 15.3 0.0 3 8.1 0.0 2.3 2 0 0 2 2 2 0 BRCA1-associated protein 2 RRM_7 PF16367.5 KFP08636.1 - 0.022 14.8 0.0 11 6.3 0.0 2.6 2 1 0 2 2 2 0 RNA recognition motif ecTbetaR2 PF08917.10 KFP08637.1 - 1.1e-41 141.2 16.8 2.9e-41 139.8 16.8 1.7 1 0 0 1 1 1 1 Transforming growth factor beta receptor 2 ectodomain Pkinase_Tyr PF07714.17 KFP08637.1 - 7.7e-36 123.7 0.0 1.5e-35 122.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP08637.1 - 1.8e-33 116.0 0.0 2.9e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KFP08637.1 - 0.014 14.2 0.0 0.03 13.1 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KFP08637.1 - 0.019 13.9 1.0 0.17 10.8 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 KFP08637.1 - 0.02 14.8 0.1 0.032 14.2 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sigma_reg_N PF13800.6 KFP08637.1 - 0.12 12.7 0.2 0.31 11.3 0.2 1.6 1 0 0 1 1 1 0 Sigma factor regulator N-terminal FixQ PF05545.11 KFP08637.1 - 0.2 11.6 0.1 0.52 10.3 0.1 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Pyridoxal_deC PF00282.19 KFP08638.1 - 2.5e-115 385.2 0.0 2.9e-115 385.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KFP08638.1 - 6.8e-06 25.3 0.0 2.3e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFP08638.1 - 3.2e-05 23.4 0.0 4.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 KFP08638.1 - 0.1 11.2 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS STT3 PF02516.14 KFP08639.1 - 6.4e-134 447.5 37.4 2.9e-132 442.1 33.7 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Oxysterol_BP PF01237.18 KFP08640.1 - 1.5e-84 284.0 3.4 1.1e-82 277.9 3.4 2.2 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 KFP08640.1 - 2.8e-08 33.9 0.0 5.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFP08640.1 - 4.1e-07 30.5 0.5 1.9e-06 28.3 0.0 2.4 3 0 0 3 3 3 1 PH domain PH_6 PF15406.6 KFP08640.1 - 0.011 16.0 0.0 0.038 14.3 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain PH_13 PF16652.5 KFP08640.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain PH_16 PF17838.1 KFP08640.1 - 0.15 11.9 0.0 0.39 10.6 0.0 1.7 1 0 0 1 1 1 0 PH domain NAD_Gly3P_dh_C PF07479.14 KFP08641.1 - 3.5e-51 173.2 0.2 7.1e-51 172.2 0.2 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KFP08641.1 - 1.7e-45 154.8 0.6 2.7e-45 154.1 0.2 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF643 PF04867.12 KFP08641.1 - 0.12 13.0 0.1 0.36 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF643) MARVEL PF01284.23 KFP08642.1 - 1.1e-18 67.6 18.3 1.4e-18 67.3 18.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain Retrotran_gag_3 PF14244.6 KFP08642.1 - 0.38 10.6 1.4 0.41 10.5 0.1 1.7 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type TMEM138 PF14935.6 KFP08642.1 - 1.9 9.2 13.7 4.3 8.0 6.0 2.1 1 1 1 2 2 2 0 Transmembrane protein 138 HRG PF16954.5 KFP08642.1 - 9.3 6.7 19.6 0.35 11.3 6.1 3.2 2 1 1 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene MARVEL PF01284.23 KFP08643.1 - 4.3e-13 49.5 16.9 7.8e-13 48.7 16.9 1.4 1 1 0 1 1 1 1 Membrane-associating domain Herpes_LMP1 PF05297.11 KFP08643.1 - 0.18 10.9 3.8 0.21 10.7 3.8 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DLIC PF05783.11 KFP08645.1 - 4.8e-240 797.2 0.0 5.7e-240 797.0 0.0 1.0 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) Roc PF08477.13 KFP08645.1 - 0.01 16.0 0.1 0.038 14.2 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TPR_1 PF00515.28 KFP08646.1 - 9.2e-15 53.8 15.4 2.1e-05 24.2 0.1 7.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFP08646.1 - 4.7e-13 48.2 25.6 0.00097 19.1 0.0 8.9 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFP08646.1 - 5.3e-08 33.0 16.3 0.024 14.9 0.3 7.3 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFP08646.1 - 4e-06 27.2 18.5 1.5 9.4 0.0 9.0 8 2 2 10 10 10 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFP08646.1 - 6.7e-06 25.9 12.5 0.001 19.1 0.0 6.2 6 0 0 6 6 5 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KFP08646.1 - 9.9e-06 25.6 3.3 0.063 13.3 0.2 3.6 3 1 0 3 3 3 2 Putative TPR-like repeat TPR_7 PF13176.6 KFP08646.1 - 1.2e-05 25.0 2.1 0.024 14.6 0.0 5.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFP08646.1 - 1.3e-05 25.6 5.2 12 7.1 0.0 7.4 8 1 1 9 9 8 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFP08646.1 - 0.001 18.9 2.9 1.3 9.0 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP08646.1 - 0.0012 19.0 25.4 3.1 8.1 0.4 7.5 7 2 0 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KFP08646.1 - 0.0026 18.0 13.3 4.7 7.8 0.1 7.1 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP08646.1 - 0.016 14.6 3.7 1 8.7 0.0 3.0 3 0 0 3 3 3 0 MalT-like TPR region TPR_16 PF13432.6 KFP08646.1 - 0.031 14.9 0.2 5.3 7.8 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF948 PF06103.11 KFP08646.1 - 0.26 11.6 0.8 0.95 9.8 0.5 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TPR_6 PF13174.6 KFP08646.1 - 0.42 11.3 7.8 28 5.6 0.0 6.0 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFP08646.1 - 0.73 9.6 4.9 8.7 6.1 0.0 4.6 5 0 0 5 5 5 0 TPR repeat CDC37_M PF08565.11 KFP08646.1 - 2.5 8.1 4.9 14 5.6 0.1 3.3 2 2 1 3 3 3 0 Cdc37 Hsp90 binding domain NHL PF01436.21 KFP08647.1 - 3e-55 181.6 16.3 5.5e-11 41.9 0.1 6.7 6 0 0 6 6 6 6 NHL repeat Filamin PF00630.19 KFP08647.1 - 1.4e-17 64.4 0.0 7.3e-17 62.1 0.0 2.2 2 0 0 2 2 2 1 Filamin/ABP280 repeat DUF5128 PF17170.4 KFP08647.1 - 1.2e-15 57.5 1.1 9.8e-06 24.9 0.0 4.3 2 2 2 4 4 4 4 6-bladed beta-propeller SGL PF08450.12 KFP08647.1 - 5.7e-11 42.5 0.5 0.0082 15.7 0.0 6.0 2 2 4 6 6 6 2 SMP-30/Gluconolactonase/LRE-like region zf-B_box PF00643.24 KFP08647.1 - 1.8e-07 31.2 2.6 5.4e-07 29.7 2.6 1.9 1 0 0 1 1 1 1 B-box zinc finger MAP65_ASE1 PF03999.12 KFP08647.1 - 0.011 14.4 1.6 0.015 14.0 1.6 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) potato_inhibit PF00280.18 KFP08647.1 - 0.04 14.6 3.9 39 5.0 0.1 5.0 5 0 0 5 5 5 0 Potato inhibitor I family DUF4094 PF13334.6 KFP08647.1 - 0.75 10.3 3.0 0.93 10.0 1.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) CLZ PF16526.5 KFP08647.1 - 8.6 6.8 7.5 7.5 7.0 1.5 2.3 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4461 PF14688.6 KFP08648.1 - 3e-122 408.3 0.9 3e-122 408.3 0.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4461) DUF4460 PF14687.6 KFP08648.1 - 6.3e-39 132.4 0.1 1.6e-38 131.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) YkyA PF10368.9 KFP08648.1 - 0.49 10.1 4.4 0.25 11.0 1.6 1.9 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Asp_Glu_race_2 PF14669.6 KFP08649.1 - 8.6e-92 305.6 0.2 3.8e-91 303.5 0.1 2.1 2 0 0 2 2 2 1 Putative aspartate racemase PPR PF01535.20 KFP08649.1 - 0.0093 16.1 1.7 28 5.2 0.0 5.8 7 0 0 7 7 7 1 PPR repeat Abhydrolase_1 PF00561.20 KFP08650.1 - 3.5e-21 76.0 0.0 1.1e-20 74.4 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFP08650.1 - 7.1e-16 59.5 0.0 9.2e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFP08650.1 - 7.8e-13 48.2 0.0 1.2e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KFP08650.1 - 0.00064 18.5 0.0 0.002 16.9 0.0 1.7 2 0 0 2 2 2 1 Ndr family Abhydrolase_3 PF07859.13 KFP08650.1 - 0.053 13.4 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 KFP08650.1 - 0.073 11.6 0.0 0.14 10.7 0.0 1.4 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_2 PF02230.16 KFP08650.1 - 0.11 12.2 0.0 11 5.7 0.0 2.4 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase DUF1071 PF06378.11 KFP08650.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) Anoctamin PF04547.12 KFP08651.1 - 8.7e-125 417.1 22.8 1e-124 416.8 22.8 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF898 PF05987.13 KFP08651.1 - 2 7.4 12.4 0.015 14.3 2.4 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF898) Pkinase PF00069.25 KFP08652.1 - 1.8e-74 250.5 0.0 3.1e-74 249.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP08652.1 - 7.4e-42 143.4 0.0 1.1e-41 142.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP08652.1 - 7.7e-10 38.6 0.0 4.9e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFP08652.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF563 PF04577.14 KFP08653.1 - 3.3e-21 76.4 0.2 6.2e-21 75.5 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) FAM198 PF15051.6 KFP08654.1 - 3.2e-124 414.0 0.0 3.6e-124 413.8 0.0 1.0 1 0 0 1 1 1 1 FAM198 protein Ribosomal_L14e PF01929.17 KFP08655.1 - 1.3e-30 105.7 7.8 2.8e-30 104.6 7.8 1.6 1 0 0 1 1 1 1 Ribosomal protein L14 DRY_EERY PF09750.9 KFP08655.1 - 0.0096 16.2 3.4 0.013 15.8 3.4 1.2 1 0 0 1 1 1 1 Alternative splicing regulator KOW PF00467.29 KFP08655.1 - 0.01 15.8 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 0 KOW motif AIG2_2 PF13772.6 KFP08656.1 - 2.2e-29 101.7 0.0 3e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.12 KFP08656.1 - 5.2e-06 27.1 0.0 7.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like XG_FTase PF03254.13 KFP08656.1 - 0.0035 16.0 0.0 0.0062 15.2 0.0 1.3 1 1 1 2 2 2 1 Xyloglucan fucosyltransferase GluR_Homer-bdg PF10606.9 KFP08656.1 - 0.15 12.3 0.2 0.55 10.5 0.1 1.9 2 0 0 2 2 2 0 Homer-binding domain of metabotropic glutamate receptor NACHT PF05729.12 KFP08657.1 - 4.3e-33 114.6 0.0 1e-32 113.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain LRR_6 PF13516.6 KFP08657.1 - 4.3e-19 66.9 3.9 0.0053 16.7 0.0 8.6 8 0 0 8 8 8 4 Leucine Rich repeat NLRC4_HD2 PF17776.1 KFP08657.1 - 5.9e-19 68.9 1.8 2.1e-18 67.1 1.8 2.0 1 0 0 1 1 1 1 NLRC4 helical domain HD2 CARD PF00619.21 KFP08657.1 - 9e-16 57.7 0.5 2.1e-14 53.3 0.1 3.1 3 0 0 3 3 3 1 Caspase recruitment domain NOD2_WH PF17779.1 KFP08657.1 - 6.4e-14 52.0 5.5 5.3e-13 49.1 0.4 3.9 3 0 0 3 3 3 1 NOD2 winged helix domain LRR_4 PF12799.7 KFP08657.1 - 5.3e-06 26.7 3.3 0.15 12.5 0.0 5.3 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) AAA_16 PF13191.6 KFP08657.1 - 0.0018 18.7 0.0 0.006 17.0 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain SpoU_sub_bind PF08032.12 KFP08657.1 - 0.013 15.8 1.9 3.2 8.1 0.0 4.0 2 1 2 4 4 4 0 RNA 2'-O ribose methyltransferase substrate binding AAA_22 PF13401.6 KFP08657.1 - 0.076 13.3 0.0 0.3 11.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFP08657.1 - 0.16 11.9 0.3 4.3 7.2 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase DUF4581 PF15167.6 KFP08658.1 - 5.9e-49 165.5 0.5 6.5e-49 165.4 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4581) Toxin_27 PF08099.11 KFP08658.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Scorpion calcine family EAF PF09816.9 KFP08659.1 - 1.9e-24 86.0 0.0 4.4e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Methyltransf_12 PF08242.12 KFP08660.1 - 8.2e-18 65.0 0.1 7.3e-17 61.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP08660.1 - 4.9e-15 56.0 0.0 1.2e-14 54.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP08660.1 - 4.9e-14 52.5 0.0 6.7e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP08660.1 - 2.1e-11 44.3 0.1 5.6e-11 43.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP08660.1 - 7.1e-10 38.9 0.0 9.9e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KFP08660.1 - 9.5e-05 22.1 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 KFP08660.1 - 0.00032 20.1 0.0 0.00051 19.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KFP08660.1 - 0.0011 18.6 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.18 KFP08660.1 - 0.032 13.7 0.4 4.6 6.7 0.1 2.4 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Thioredoxin PF00085.20 KFP08661.1 - 9.2e-98 321.1 0.8 4.1e-32 110.2 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.6 KFP08661.1 - 2.1e-21 76.6 8.7 4.6e-14 52.8 1.0 4.8 4 1 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFP08661.1 - 5.7e-18 65.0 2.3 0.0024 18.2 0.0 6.5 4 2 2 6 6 6 4 Thioredoxin-like OST3_OST6 PF04756.13 KFP08661.1 - 5.3e-16 58.8 0.1 1.7e-05 24.3 0.0 3.2 3 0 0 3 3 3 3 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KFP08661.1 - 6e-16 58.8 1.8 0.0016 18.9 0.1 4.6 3 1 0 3 3 3 3 Thioredoxin-like domain Calsequestrin PF01216.17 KFP08661.1 - 6e-14 51.9 3.4 3e-12 46.3 0.1 2.8 1 1 0 2 2 2 2 Calsequestrin Thioredoxin_7 PF13899.6 KFP08661.1 - 2.6e-11 43.5 0.0 0.035 14.3 0.0 3.9 3 0 0 3 3 3 3 Thioredoxin-like AhpC-TSA PF00578.21 KFP08661.1 - 6.6e-10 39.0 0.8 0.078 12.9 0.0 4.2 3 1 1 4 4 4 3 AhpC/TSA family TraF PF13728.6 KFP08661.1 - 1.5e-07 31.5 0.0 0.031 14.1 0.0 3.4 3 0 0 3 3 3 2 F plasmid transfer operon protein Redoxin PF08534.10 KFP08661.1 - 8.2e-07 28.8 0.3 0.77 9.5 0.0 4.2 4 0 0 4 4 4 3 Redoxin Thioredoxin_4 PF13462.6 KFP08661.1 - 1.2e-05 25.5 2.9 3.1 7.9 0.0 4.3 4 0 0 4 4 4 3 Thioredoxin HyaE PF07449.11 KFP08661.1 - 0.00022 21.2 0.0 7 6.7 0.0 3.7 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 KFP08661.1 - 0.0027 17.4 0.1 3.6 7.4 0.0 3.3 3 0 0 3 3 3 1 Thioredoxin DUF836 PF05768.14 KFP08661.1 - 0.0053 17.1 0.0 11 6.5 0.0 3.5 3 0 0 3 3 3 0 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 KFP08661.1 - 0.017 14.9 2.0 35 4.1 0.1 4.8 3 3 3 6 6 6 0 DSBA-like thioredoxin domain Glutaredoxin PF00462.24 KFP08661.1 - 0.089 13.0 3.2 7.7 6.8 0.0 4.1 3 1 0 3 3 3 0 Glutaredoxin Thioredoxin_5 PF13743.6 KFP08661.1 - 2.1 8.0 6.6 53 3.4 0.1 4.6 4 1 1 5 5 5 0 Thioredoxin PRC2_HTH_1 PF18118.1 KFP08662.1 - 7.8e-31 106.9 4.2 7.8e-31 106.9 4.2 2.7 2 0 0 2 2 2 1 Polycomb repressive complex 2 tri-helical domain SET PF00856.28 KFP08662.1 - 4.4e-18 66.3 6.7 6.5e-18 65.7 0.5 3.1 2 2 0 2 2 2 1 SET domain EZH2_WD-Binding PF11616.8 KFP08662.1 - 3e-16 59.2 3.5 7.3e-16 58.0 3.5 1.7 1 0 0 1 1 1 1 WD repeat binding protein EZH2 preSET_CXC PF18264.1 KFP08662.1 - 4.8e-12 46.1 15.6 4.8e-12 46.1 15.6 3.9 2 1 0 2 2 2 1 CXC domain CDC45 PF02724.14 KFP08662.1 - 6 5.0 8.1 8.2 4.6 2.3 2.1 2 0 0 2 2 2 0 CDC45-like protein Cullin PF00888.22 KFP08664.1 - 1.7e-166 555.4 12.8 1.7e-166 555.4 12.8 1.5 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 KFP08664.1 - 2.6e-28 97.8 2.8 1.7e-27 95.2 1.9 2.6 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF4980 PF16352.5 KFP08664.1 - 0.18 11.8 1.7 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4980) Laminin_G_2 PF02210.24 KFP08665.1 - 1.4e-46 158.1 0.0 1.1e-23 84.2 0.1 2.3 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 KFP08665.1 - 7.4e-31 107.1 0.0 1.4e-14 54.5 0.1 2.5 2 1 0 2 2 2 2 Laminin G domain Laminin_G_3 PF13385.6 KFP08665.1 - 9.6e-06 25.8 0.1 0.0001 22.4 0.0 2.2 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 KFP08665.1 - 0.00022 21.5 7.4 0.00051 20.3 7.4 1.7 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 KFP08665.1 - 0.0089 16.6 5.7 0.0089 16.6 5.7 2.1 2 0 0 2 2 2 1 Human growth factor-like EGF Syndecan PF01034.20 KFP08665.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain MARVEL PF01284.23 KFP08665.1 - 0.096 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Membrane-associating domain MAP17 PF15807.5 KFP08665.1 - 0.21 11.8 0.0 0.37 11.0 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 TAFA PF12020.8 KFP08666.1 - 1.1e-32 112.3 9.0 1.5e-32 111.9 9.0 1.1 1 0 0 1 1 1 1 TAFA family Lipase_GDSL_2 PF13472.6 KFP08667.1 - 0.0016 18.9 0.0 0.0031 18.0 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 KFP08667.1 - 0.0046 16.2 0.0 0.0089 15.3 0.0 1.4 1 0 0 1 1 1 1 OSK domain Lipase_GDSL PF00657.22 KFP08667.1 - 0.22 11.5 0.0 0.85 9.6 0.0 1.9 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase UCH PF00443.29 KFP08668.1 - 1.3e-84 283.7 0.2 1.8e-84 283.3 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_3 PF14836.6 KFP08668.1 - 2.5e-40 136.3 0.1 5.3e-40 135.3 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain DUSP PF06337.12 KFP08668.1 - 3.8e-19 69.1 0.9 3.8e-19 69.1 0.9 2.4 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 KFP08668.1 - 1e-14 54.9 0.4 5.4e-08 32.8 0.0 3.5 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 KFP08668.1 - 1.9e-08 34.3 0.8 6.7e-07 29.2 0.0 2.9 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.8 KFP08668.1 - 0.00036 19.9 0.0 0.0009 18.6 0.0 1.6 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 Mon2_C PF16206.5 KFP08669.1 - 0 1340.9 4.2 0 1339.8 3.8 1.7 2 0 0 2 2 2 1 C-terminal region of Mon2 protein DCB PF16213.5 KFP08669.1 - 1e-57 194.7 7.9 3e-57 193.2 6.1 2.9 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 KFP08669.1 - 7.3e-55 185.2 2.4 7.3e-55 185.2 2.4 2.9 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KFP08669.1 - 6.8e-19 67.5 0.2 1.8e-16 59.8 0.0 4.2 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) HEAT PF02985.22 KFP08669.1 - 4.7e-05 23.3 1.3 14 6.3 0.0 5.5 4 0 0 4 4 4 1 HEAT repeat Keratin_assoc PF09775.9 KFP08669.1 - 0.061 13.0 0.0 0.66 9.6 0.1 2.5 2 0 0 2 2 2 0 Keratinocyte-associated protein 2 SelK_SelG PF10961.8 KFP08669.1 - 0.93 10.1 3.0 0.83 10.3 0.7 2.1 2 0 0 2 2 2 0 Selenoprotein SelK_SelG PP2C PF00481.21 KFP08670.1 - 8.2e-27 94.5 0.0 4.5e-12 46.1 0.0 3.0 3 0 0 3 3 3 3 Protein phosphatase 2C SpoIIE PF07228.12 KFP08670.1 - 0.00013 21.9 0.0 0.16 11.9 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KFP08670.1 - 0.017 14.7 0.0 0.11 12.1 0.0 2.2 1 1 0 1 1 1 0 Protein phosphatase 2C Exostosin PF03016.15 KFP08671.1 - 4.5e-07 29.4 0.1 9.5e-07 28.3 0.0 1.6 2 0 0 2 2 2 1 Exostosin family RhoGAP PF00620.27 KFP08672.1 - 1.1e-46 158.4 0.4 1.3e-45 155.0 0.0 2.8 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 KFP08672.1 - 3.7e-17 62.4 6.5 8.3e-17 61.2 5.3 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KFP08672.1 - 4.9e-10 38.8 0.0 9.2e-10 38.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP08672.1 - 7.7e-10 38.5 0.0 1.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP08672.1 - 1.1e-08 34.7 0.0 2.3e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain FlaC_arch PF05377.11 KFP08672.1 - 0.57 10.6 6.1 0.2 12.1 1.1 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) C12orf66_like PF09404.10 KFP08673.1 - 1.4e-246 818.4 8.9 1.6e-246 818.2 8.9 1.0 1 0 0 1 1 1 1 KICSTOR complex C12orf66 like Urb2 PF10441.9 KFP08673.1 - 0.04 13.9 0.7 0.08 12.9 0.4 1.6 1 1 0 1 1 1 0 Urb2/Npa2 family RNase_3_N PF18497.1 KFP08673.1 - 0.076 13.2 1.5 1.4 9.1 0.1 2.7 2 1 0 2 2 2 0 Ribonuclease III N-terminal domain Pox_I1 PF03289.13 KFP08673.1 - 0.093 11.8 0.5 0.62 9.1 0.1 2.1 2 0 0 2 2 2 0 Poxvirus protein I1 Ribosomal_L18A PF01775.17 KFP08674.1 - 6.9e-57 190.8 0.1 8.6e-57 190.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A C1_1 PF00130.22 KFP08675.1 - 0.071 13.0 5.1 0.1 12.5 5.1 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RA PF00788.23 KFP08676.1 - 2.5e-20 72.9 0.1 2.5e-19 69.7 0.1 2.2 1 1 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Nore1-SARAH PF16517.5 KFP08676.1 - 9e-16 57.5 5.1 9e-16 57.5 5.1 1.8 2 0 0 2 2 2 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Mst1_SARAH PF11629.8 KFP08676.1 - 0.022 14.8 1.0 0.046 13.8 1.0 1.5 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 Ras_bdg_2 PF14847.6 KFP08676.1 - 0.039 14.3 0.0 0.096 13.0 0.0 1.6 1 0 0 1 1 1 0 Ras-binding domain of Byr2 RBD PF02196.15 KFP08676.1 - 0.039 14.0 0.0 0.091 12.9 0.0 1.7 1 0 0 1 1 1 0 Raf-like Ras-binding domain Stk19 PF10494.9 KFP08676.1 - 0.14 11.8 0.1 0.21 11.3 0.1 1.5 1 1 0 1 1 1 0 Serine-threonine protein kinase 19 DUF4682 PF15733.5 KFP08677.1 - 3.3e-43 147.3 3.6 3.3e-43 147.3 3.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4682) RabGAP-TBC PF00566.18 KFP08677.1 - 1.2e-36 126.4 1.2 2e-36 125.7 0.1 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain 60KD_IMP PF02096.20 KFP08677.1 - 0.02 14.8 0.4 0.02 14.8 0.4 2.5 3 0 0 3 3 3 0 60Kd inner membrane protein WIF PF02019.18 KFP08679.1 - 2.4e-24 85.5 0.0 3.2e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 WIF domain EGF_2 PF07974.13 KFP08679.1 - 4.3e-20 71.8 89.0 0.00014 22.2 10.3 5.3 5 0 0 5 5 5 5 EGF-like domain hEGF PF12661.7 KFP08679.1 - 3.9e-12 46.3 65.0 0.00046 20.7 6.5 6.1 5 0 0 5 5 5 5 Human growth factor-like EGF EGF PF00008.27 KFP08679.1 - 7.1e-11 42.2 86.0 0.00043 20.5 8.6 5.5 5 0 0 5 5 5 4 EGF-like domain DSL PF01414.19 KFP08679.1 - 0.039 14.2 8.6 0.039 14.2 8.6 3.8 2 2 1 3 3 3 0 Delta serrate ligand Laminin_EGF PF00053.24 KFP08679.1 - 2.7 8.2 70.6 3.7 7.8 9.4 5.3 1 1 4 5 5 5 0 Laminin EGF domain MSC PF09402.10 KFP08680.1 - 3.6e-20 72.7 0.6 5.9e-20 72.0 0.6 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain RBM39linker PF15519.6 KFP08680.1 - 0.0017 19.4 0.1 0.0071 17.4 0.0 2.0 2 0 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein SelR PF01641.18 KFP08681.1 - 2e-53 179.6 0.2 2.5e-53 179.3 0.2 1.1 1 0 0 1 1 1 1 SelR domain zf-ribbon_3 PF13248.6 KFP08681.1 - 0.0053 16.1 1.0 0.49 9.9 0.1 2.7 2 0 0 2 2 2 1 zinc-ribbon domain Yippee-Mis18 PF03226.14 KFP08681.1 - 0.02 15.1 0.1 0.046 13.9 0.1 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.7 KFP08681.1 - 0.033 14.2 0.2 0.26 11.3 0.2 2.4 1 1 0 1 1 1 0 Double zinc ribbon Zn_ribbon_SprT PF17283.2 KFP08681.1 - 0.038 13.9 0.8 0.5 10.3 0.9 2.4 1 1 0 1 1 1 0 SprT-like zinc ribbon domain zf-Mss51 PF13824.6 KFP08681.1 - 0.045 13.9 2.8 0.2 11.8 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 GFA PF04828.14 KFP08681.1 - 0.051 13.9 1.7 1.4 9.3 0.3 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_10 PF10058.9 KFP08681.1 - 0.093 12.5 0.7 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zinc_ribbon_2 PF13240.6 KFP08681.1 - 0.68 9.7 4.1 8 6.3 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zf-tcix PF14952.6 KFP08681.1 - 4.3 7.0 6.5 25 4.6 0.2 3.2 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding AT_hook PF02178.19 KFP08682.1 - 0.0085 15.9 27.1 0.079 12.9 7.2 3.2 3 1 0 3 3 3 2 AT hook motif Laps PF10169.9 KFP08684.1 - 1.3e-36 126.0 24.9 1e-35 123.1 24.9 1.9 1 1 0 1 1 1 1 Learning-associated protein DUF2423 PF10338.9 KFP08684.1 - 0.00028 21.0 8.0 0.00028 21.0 8.0 3.0 3 1 0 3 3 3 1 Protein of unknown function (DUF2423) Bax1-I PF01027.20 KFP08685.1 - 5.2e-49 166.9 27.0 5.9e-49 166.7 27.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 KFP08685.1 - 0.06 12.9 19.5 0.15 11.6 19.5 1.6 1 1 0 1 1 1 0 Bax inhibitor 1 like 7TMR-DISM_7TM PF07695.11 KFP08685.1 - 0.56 10.1 27.6 2.6 7.9 14.0 2.2 1 1 1 2 2 2 0 7TM diverse intracellular signalling Vma12 PF11712.8 KFP08685.1 - 2.5 8.2 10.7 4 7.5 6.2 2.5 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase AAA_30 PF13604.6 KFP08686.1 - 1.2e-27 96.9 0.0 8.3e-27 94.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFP08686.1 - 1.4e-14 54.7 0.0 6.6e-14 52.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KFP08686.1 - 8.7e-09 35.5 1.0 0.077 12.7 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 KFP08686.1 - 1.8e-07 30.9 2.3 4.9e-07 29.5 2.3 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 KFP08686.1 - 7.7e-05 22.6 0.2 0.017 15.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KFP08686.1 - 0.00062 20.3 0.0 0.0025 18.3 0.0 2.1 2 0 0 2 2 1 1 ABC transporter ParA PF10609.9 KFP08686.1 - 0.00067 19.2 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase RsgA_GTPase PF03193.16 KFP08686.1 - 0.001 19.0 0.1 0.0025 17.7 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase CbiA PF01656.23 KFP08686.1 - 0.0012 18.9 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 KFP08686.1 - 0.0025 18.2 0.3 0.0078 16.6 0.3 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFP08686.1 - 0.0026 18.1 0.5 0.22 11.8 0.2 3.6 3 1 0 3 3 3 1 AAA domain Mpp10 PF04006.12 KFP08686.1 - 0.0034 15.9 6.8 0.0051 15.3 6.8 1.1 1 0 0 1 1 1 1 Mpp10 protein AAA_15 PF13175.6 KFP08686.1 - 0.015 15.0 0.6 0.032 14.0 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 KFP08686.1 - 0.031 13.5 0.4 0.1 11.8 0.1 2.1 2 0 0 2 2 2 0 NB-ARC domain ArsA_ATPase PF02374.15 KFP08686.1 - 0.039 13.1 0.7 0.67 9.1 0.2 2.8 2 1 1 3 3 3 0 Anion-transporting ATPase AAA_14 PF13173.6 KFP08686.1 - 0.045 13.8 0.0 0.29 11.2 0.0 2.5 2 1 1 3 3 3 0 AAA domain DUF4888 PF16229.5 KFP08686.1 - 0.098 12.6 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4888) PDZ PF00595.24 KFP08687.1 - 5.7e-89 292.6 7.2 4.5e-14 52.6 0.0 7.3 7 0 0 7 7 7 7 PDZ domain PDZ_6 PF17820.1 KFP08687.1 - 6.2e-67 221.3 4.9 1.3e-11 44.1 0.0 7.4 7 0 0 7 7 7 7 PDZ domain PDZ_2 PF13180.6 KFP08687.1 - 1.2e-34 118.5 3.8 2e-05 24.8 0.0 7.5 7 0 0 7 7 7 7 PDZ domain Tricorn_PDZ PF14685.6 KFP08687.1 - 1.6e-11 44.0 1.3 0.66 10.0 0.0 6.1 6 0 0 6 6 6 4 Tricorn protease PDZ domain GRASP55_65 PF04495.14 KFP08687.1 - 0.00075 19.8 0.0 5 7.4 0.0 4.0 2 2 2 4 4 4 2 GRASP55/65 PDZ-like domain FTH PF01827.27 KFP08687.1 - 0.11 12.3 0.0 0.99 9.2 0.0 2.4 3 0 0 3 3 3 0 FTH domain EutA PF06277.11 KFP08687.1 - 0.24 10.2 2.3 0.48 9.2 0.1 2.3 3 0 0 3 3 3 0 Ethanolamine utilisation protein EutA TIP120 PF08623.10 KFP08688.1 - 3.2e-67 225.5 8.8 7.1e-65 217.9 0.8 5.6 4 1 2 6 6 6 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 KFP08688.1 - 5.1e-22 78.1 1.1 0.011 16.1 0.0 9.5 7 2 2 9 9 9 5 HEAT repeats HEAT_EZ PF13513.6 KFP08688.1 - 4.6e-21 74.9 7.1 0.00039 20.8 0.1 11.9 10 2 3 13 13 12 3 HEAT-like repeat HEAT PF02985.22 KFP08688.1 - 2.2e-18 64.7 19.5 0.079 13.3 0.0 13.1 16 0 0 16 16 11 5 HEAT repeat UME PF08064.13 KFP08688.1 - 1.9e-13 50.2 6.7 0.0083 16.0 0.1 8.1 6 2 1 8 8 8 2 UME (NUC010) domain CLASP_N PF12348.8 KFP08688.1 - 4.3e-09 36.3 2.8 0.077 12.5 0.0 6.2 6 1 1 7 7 7 2 CLASP N terminal Vac14_Fab1_bd PF12755.7 KFP08688.1 - 6e-09 36.4 6.8 0.0086 16.7 0.1 7.4 7 2 2 9 9 8 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KFP08688.1 - 9.8e-09 34.3 14.7 0.00028 19.6 0.2 6.0 2 2 2 5 5 5 4 Adaptin N terminal region Telomere_reg-2 PF10193.9 KFP08688.1 - 4.6e-08 33.5 6.3 0.49 10.8 0.0 6.8 7 0 0 7 7 5 1 Telomere length regulation protein Cnd1 PF12717.7 KFP08688.1 - 7.4e-08 32.6 17.2 0.055 13.5 0.4 7.8 7 1 2 9 9 8 3 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 KFP08688.1 - 6e-07 28.9 20.9 0.00021 20.6 0.6 7.2 6 2 2 8 8 8 2 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 KFP08688.1 - 3.9e-06 27.0 10.2 1.1 9.4 0.1 7.8 8 1 1 9 9 8 1 Required for nuclear transport of RNA pol II C-terminus 1 DRIM PF07539.12 KFP08688.1 - 0.00016 20.2 8.7 0.17 10.1 0.2 5.2 3 1 3 6 6 6 2 Down-regulated in metastasis DUF3385 PF11865.8 KFP08688.1 - 0.00022 21.1 9.5 0.00076 19.4 0.1 5.7 7 2 0 7 7 6 1 Domain of unknown function (DUF3385) RIX1 PF08167.12 KFP08688.1 - 0.00075 19.3 8.2 6.5 6.4 0.2 6.3 4 1 1 6 6 6 1 rRNA processing/ribosome biogenesis TAF6_C PF07571.13 KFP08688.1 - 0.0053 17.1 0.1 3.6 8.0 0.0 4.6 3 2 0 3 3 3 1 TAF6 C-terminal HEAT repeat domain API5 PF05918.11 KFP08688.1 - 0.0054 15.6 5.7 5 5.8 0.4 5.1 6 1 0 7 7 7 2 Apoptosis inhibitory protein 5 (API5) V-ATPase_H_N PF03224.14 KFP08688.1 - 0.0064 15.8 5.8 1.6 8.0 0.3 4.7 3 1 2 5 5 5 1 V-ATPase subunit H VHS PF00790.19 KFP08688.1 - 0.0066 16.3 0.5 1.8 8.4 0.1 4.1 3 0 0 3 3 3 1 VHS domain NUC173 PF08161.12 KFP08688.1 - 0.0088 15.7 2.0 14 5.2 0.0 5.3 5 2 1 6 6 6 0 NUC173 domain RRN3 PF05327.11 KFP08688.1 - 0.023 13.2 0.5 0.075 11.6 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Uso1_p115_head PF04869.14 KFP08688.1 - 0.036 13.2 0.1 0.27 10.3 0.1 2.5 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, head region Dopey_N PF04118.14 KFP08688.1 - 0.05 12.7 2.0 5.6 6.0 0.1 3.6 2 1 1 3 3 3 0 Dopey, N-terminal GhoS PF11080.8 KFP08688.1 - 0.16 11.9 0.0 0.66 10.0 0.0 2.0 1 0 0 1 1 1 0 Endoribonuclease GhoS V-ATPase_H_C PF11698.8 KFP08688.1 - 0.2 11.8 9.0 26 5.0 0.1 6.2 7 1 0 8 8 7 0 V-ATPase subunit H RasGEF_N_2 PF14663.6 KFP08688.1 - 0.49 10.8 2.8 40 4.7 0.1 4.5 4 0 0 4 4 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF4042 PF13251.6 KFP08688.1 - 2 8.1 5.7 46 3.6 0.0 5.1 5 0 0 5 5 5 0 Domain of unknown function (DUF4042) Pkinase PF00069.25 KFP08689.1 - 3.5e-59 200.3 0.0 5.2e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP08689.1 - 5e-23 81.7 0.1 1.4e-22 80.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFP08689.1 - 3e-06 27.4 0.0 0.00019 21.5 0.0 2.4 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFP08689.1 - 0.0019 17.6 0.5 0.0041 16.5 0.5 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFP08689.1 - 0.0027 17.3 3.4 0.0045 16.6 3.4 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KFP08689.1 - 0.02 14.5 2.1 0.08 12.5 2.1 1.9 1 1 0 1 1 1 0 RIO1 family WaaY PF06176.11 KFP08689.1 - 0.026 14.1 2.5 0.041 13.5 2.5 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Kinase-like PF14531.6 KFP08689.1 - 0.03 13.6 0.1 0.18 11.1 0.0 1.9 1 1 1 2 2 2 0 Kinase-like YrbL-PhoP_reg PF10707.9 KFP08689.1 - 0.075 12.6 1.4 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 KFP08689.1 - 0.21 11.2 1.8 0.9 9.1 0.2 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 IFN-gamma PF00714.17 KFP08690.1 - 8.8e-30 103.4 0.7 1.1e-29 103.1 0.7 1.1 1 0 0 1 1 1 1 Interferon gamma Lipoprotein_20 PF13942.6 KFP08690.1 - 0.00032 20.7 1.2 0.00041 20.3 1.2 1.3 1 0 0 1 1 1 1 YfhG lipoprotein Fib_alpha PF08702.10 KFP08690.1 - 0.0047 17.1 1.7 0.006 16.8 0.5 1.6 1 1 0 1 1 1 1 Fibrinogen alpha/beta chain family Sec8_exocyst PF04048.14 KFP08690.1 - 0.023 14.6 3.6 0.07 13.0 1.8 2.1 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain CorA PF01544.18 KFP08690.1 - 0.29 10.4 2.8 0.22 10.8 1.1 1.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein IL10 PF00726.17 KFP08691.1 - 7.9e-10 38.5 0.0 1.4e-09 37.7 0.0 1.4 1 1 0 1 1 1 1 Interleukin 10 IL22 PF14565.6 KFP08691.1 - 6.7e-05 23.2 0.0 0.00011 22.5 0.0 1.3 1 1 0 1 1 1 1 Interleukin 22 IL-10-related T-cell-derived-inducible factor IL22 PF14565.6 KFP08692.1 - 3e-58 196.0 0.8 3.5e-58 195.8 0.8 1.0 1 0 0 1 1 1 1 Interleukin 22 IL-10-related T-cell-derived-inducible factor IL10 PF00726.17 KFP08692.1 - 0.0016 18.0 0.1 0.0018 17.8 0.1 1.1 1 0 0 1 1 1 1 Interleukin 10 MDM1 PF15501.6 KFP08693.1 - 3.1e-152 508.6 35.6 1.6e-151 506.2 35.6 2.0 1 1 0 1 1 1 1 Nuclear protein MDM1 KCT2 PF17818.1 KFP08693.1 - 0.03 14.4 2.0 0.1 12.7 2.0 1.9 1 0 0 1 1 1 0 Keratinocyte-associated gene product Ras PF00071.22 KFP08694.1 - 2.2e-57 193.2 0.3 2.5e-57 193.0 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP08694.1 - 7.2e-21 74.6 0.0 1.1e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP08694.1 - 1.1e-08 34.7 0.2 1.2e-08 34.6 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP08694.1 - 7.1e-05 22.4 0.3 0.00019 21.0 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFP08694.1 - 0.00066 19.7 0.0 0.001 19.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP08694.1 - 0.0023 17.9 2.9 0.58 10.0 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 KFP08694.1 - 0.0038 16.4 0.0 0.0059 15.8 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit AAA_22 PF13401.6 KFP08694.1 - 0.24 11.6 0.9 12 6.2 0.5 2.7 2 1 0 2 2 2 0 AAA domain Nup84_Nup100 PF04121.13 KFP08695.1 - 7e-216 718.7 18.0 8.1e-216 718.5 18.0 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 TPT PF03151.16 KFP08696.1 - 6.4e-18 65.1 16.8 7.6e-18 64.9 16.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family zf-C3HC4_3 PF13920.6 KFP08697.1 - 2.7e-13 49.6 9.6 2.7e-13 49.6 9.6 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SWIB PF02201.18 KFP08697.1 - 7.6e-10 38.5 0.1 2.1e-09 37.1 0.1 1.8 1 1 1 2 2 2 1 SWIB/MDM2 domain zf-RanBP PF00641.18 KFP08697.1 - 1.7e-08 33.6 2.2 1.7e-08 33.6 2.2 2.5 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-RING_2 PF13639.6 KFP08697.1 - 0.016 15.5 9.5 0.016 15.5 9.5 2.4 2 1 1 3 3 3 0 Ring finger domain zf-FPG_IleRS PF06827.14 KFP08697.1 - 0.097 12.6 0.1 0.097 12.6 0.1 3.8 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS DZR PF12773.7 KFP08697.1 - 0.1 12.6 15.4 0.46 10.6 1.5 3.0 3 0 0 3 3 3 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 KFP08697.1 - 0.84 9.4 9.3 0.16 11.7 2.4 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 KFP08697.1 - 5.5 7.0 11.9 1 9.4 4.8 2.7 2 0 0 2 2 2 0 zinc-ribbons Peptidase_M14 PF00246.24 KFP08698.1 - 1.8e-77 261.0 0.1 2.4e-77 260.6 0.1 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 KFP08698.1 - 3e-12 46.7 0.0 5.7e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KFP08698.1 - 8.6e-09 35.3 0.0 1.5e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 CarboxypepD_reg-like domain AstE_AspA PF04952.14 KFP08698.1 - 1.1e-07 31.2 0.0 2.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Dioxygenase_C PF00775.21 KFP08698.1 - 0.0091 15.5 0.1 0.026 14.0 0.1 1.9 1 1 0 1 1 1 1 Dioxygenase Big_1 PF02369.16 KFP08698.1 - 0.15 12.1 0.9 0.34 10.9 0.1 2.0 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) CooC_C PF15976.5 KFP08698.1 - 0.16 12.1 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 CS1-pili formation C-terminal RRM_1 PF00076.22 KFP08699.1 - 5.1e-07 29.4 0.0 9e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc PF12871.7 KFP08699.1 - 0.0038 17.8 50.1 0.0088 16.6 50.1 1.6 1 0 0 1 1 1 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term YEATS PF03366.16 KFP08700.1 - 4.7e-34 116.2 0.4 8.1e-34 115.4 0.4 1.4 1 0 0 1 1 1 1 YEATS family SOGA PF11365.8 KFP08700.1 - 0.0072 17.4 3.0 0.014 16.5 3.0 1.5 1 0 0 1 1 1 1 Protein SOGA DUF1664 PF07889.12 KFP08700.1 - 0.2 11.7 1.1 0.31 11.1 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Pkinase PF00069.25 KFP08701.1 - 1.2e-57 195.3 0.0 1.4e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP08701.1 - 6.4e-20 71.5 0.0 8.9e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFP08701.1 - 0.00011 22.2 0.0 0.00021 21.3 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFP08701.1 - 0.0068 16.0 0.1 0.015 14.9 0.0 1.5 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KFP08701.1 - 0.0069 16.0 1.3 0.011 15.4 1.3 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KFP08701.1 - 0.046 13.1 0.2 0.085 12.2 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFP08701.1 - 0.084 11.6 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RAD51_interact PF15696.5 KFP08703.1 - 1.9e-20 72.7 2.8 1.9e-20 72.7 2.8 2.8 4 0 0 4 4 4 1 RAD51 interacting motif HoxA13_N PF12284.8 KFP08703.1 - 1.5 9.5 6.3 3.3 8.4 1.3 2.3 1 1 1 2 2 2 0 Hox protein A13 N terminal DUF2362 PF10154.9 KFP08704.1 - 1e-218 727.3 14.2 1.2e-218 727.1 14.2 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) FGF PF00167.18 KFP08705.1 - 2.4e-41 140.8 0.0 2.9e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Fibroblast growth factor GAF PF01590.26 KFP08705.1 - 0.19 12.4 0.0 0.23 12.1 0.0 1.2 1 0 0 1 1 1 0 GAF domain FGF PF00167.18 KFP08706.1 - 7.8e-22 77.7 0.0 1.1e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Fibroblast growth factor Cyclin_N PF00134.23 KFP08707.1 - 3.4e-37 127.0 1.3 6.7e-37 126.1 1.3 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP08707.1 - 6.3e-22 77.9 0.3 4.6e-21 75.1 0.0 2.2 2 1 0 2 2 2 1 Cyclin, C-terminal domain K-cyclin_vir_C PF09080.10 KFP08707.1 - 0.017 15.5 0.0 0.029 14.8 0.0 1.3 1 0 0 1 1 1 0 K cyclin, C terminal 3Beta_HSD PF01073.19 KFP08708.1 - 7.4e-13 48.1 0.0 2.4e-07 30.1 0.0 2.1 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KFP08708.1 - 7.8e-12 45.3 0.0 3.1e-11 43.3 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KFP08708.1 - 4.4e-11 42.7 0.0 1.5e-09 37.7 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFP08708.1 - 2.8e-09 37.1 0.0 6e-09 36.1 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KFP08708.1 - 2.9e-06 26.6 0.0 0.00025 20.2 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KFP08708.1 - 0.0018 17.5 0.0 0.43 9.7 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KFP08708.1 - 0.0065 15.9 0.0 0.036 13.5 0.0 2.0 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase DUF3798 PF12683.7 KFP08708.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) Glycos_transf_2 PF00535.26 KFP08709.1 - 1.8e-22 80.0 0.1 2.8e-22 79.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFP08709.1 - 4.8e-12 46.2 0.0 7.7e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 KFP08709.1 - 0.032 14.1 0.0 2.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KFP08709.1 - 0.033 13.8 0.0 0.075 12.7 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase Ion_trans PF00520.31 KFP08710.1 - 1.7e-51 174.8 0.1 2.3e-51 174.4 0.1 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFP08710.1 - 1.1e-12 47.7 7.0 1.1e-12 47.7 7.0 3.4 4 0 0 4 4 4 1 Ion channel PKD_channel PF08016.12 KFP08710.1 - 0.0055 15.4 2.7 0.012 14.3 2.7 1.6 1 1 0 1 1 1 1 Polycystin cation channel DUF423 PF04241.15 KFP08710.1 - 0.78 10.0 0.1 0.78 10.0 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF423) DUF973 PF06157.11 KFP08710.1 - 1.3 8.0 8.5 0.099 11.7 2.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF973) Sigma_reg_N PF13800.6 KFP08710.1 - 3.2 8.1 6.2 7.1 7.0 0.1 3.3 4 0 0 4 4 4 0 Sigma factor regulator N-terminal Ion_trans PF00520.31 KFP08711.1 - 5e-52 176.6 11.0 7e-52 176.1 11.0 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFP08711.1 - 1.5e-28 99.0 0.3 3.7e-28 97.7 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFP08711.1 - 6.2e-14 51.7 5.2 6.2e-14 51.7 5.2 2.8 3 0 0 3 3 3 1 Ion channel Sigma_reg_N PF13800.6 KFP08711.1 - 0.0034 17.6 2.7 4.6 7.6 0.1 3.7 3 0 0 3 3 3 1 Sigma factor regulator N-terminal PKD_channel PF08016.12 KFP08711.1 - 0.011 14.4 0.5 0.011 14.4 0.5 1.8 1 1 1 2 2 2 0 Polycystin cation channel DUF423 PF04241.15 KFP08711.1 - 2.2 8.6 3.7 1.3 9.3 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF423) ELO PF01151.18 KFP08712.1 - 2.6e-66 223.7 18.8 3e-66 223.5 18.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Ion_trans PF00520.31 KFP08713.1 - 2.1e-54 184.4 0.4 2.8e-54 183.9 0.4 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFP08713.1 - 1.1e-23 83.3 0.1 2.2e-23 82.4 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFP08713.1 - 3.4e-14 52.6 4.1 3.4e-14 52.6 4.1 2.3 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.12 KFP08713.1 - 0.0008 18.2 0.9 0.0019 16.9 0.9 1.6 1 0 0 1 1 1 1 Polycystin cation channel Sigma_reg_N PF13800.6 KFP08713.1 - 0.12 12.7 1.6 7.9 6.9 0.0 3.3 3 0 0 3 3 3 0 Sigma factor regulator N-terminal NGF PF00243.18 KFP08714.1 - 4.4e-52 175.1 2.6 4.4e-52 175.1 2.6 1.5 2 0 0 2 2 2 1 Nerve growth factor family Spaetzle PF16077.5 KFP08714.1 - 0.0011 19.4 0.4 0.0011 19.4 0.4 1.6 2 0 0 2 2 2 1 Spaetzle Anoctamin PF04547.12 KFP08715.1 - 8.9e-152 506.0 9.3 1.1e-151 505.7 9.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KFP08715.1 - 7.4e-80 267.9 0.0 1.3e-79 267.1 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Ninjurin PF04923.12 KFP08715.1 - 4.2 7.4 7.2 7.1 6.6 2.4 3.0 3 0 0 3 3 3 0 Ninjurin C8 PF08742.11 KFP08716.1 - 2.9e-15 56.4 7.0 2.9e-15 56.4 7.0 2.1 2 0 0 2 2 2 1 C8 domain TIL PF01826.17 KFP08716.1 - 1.7e-07 31.4 14.4 1.7e-07 31.4 14.4 2.7 2 1 0 2 2 2 1 Trypsin Inhibitor like cysteine rich domain VWD PF00094.25 KFP08717.1 - 1.7e-27 96.6 0.4 2.9e-27 95.9 0.4 1.4 1 1 0 1 1 1 1 von Willebrand factor type D domain zf-RRN7 PF11781.8 KFP08717.1 - 0.045 13.5 0.1 0.17 11.6 0.1 2.1 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 RGM_N PF06535.12 KFP08717.1 - 0.071 13.3 0.4 0.11 12.8 0.1 1.5 2 0 0 2 2 2 0 Repulsive guidance molecule (RGM) N-terminus Homeodomain PF00046.29 KFP08718.1 - 2.3e-23 81.8 1.6 3.2e-23 81.3 1.6 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP08718.1 - 0.00023 21.0 0.1 0.00056 19.8 0.0 1.7 2 0 0 2 2 2 1 Homeobox KN domain HTH_28 PF13518.6 KFP08718.1 - 0.02 15.0 0.1 0.032 14.4 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1510 PF07423.11 KFP08718.1 - 0.037 14.2 0.0 0.04 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1510) RE_ApaLI PF09499.10 KFP08718.1 - 0.056 13.2 0.0 0.063 13.0 0.0 1.1 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease RhoGEF PF00621.20 KFP08719.1 - 4.9e-36 124.7 2.6 4.9e-36 124.7 2.6 1.8 2 0 0 2 2 2 1 RhoGEF domain SH3_9 PF14604.6 KFP08719.1 - 5.6e-11 42.1 0.0 1.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP08719.1 - 6.4e-11 41.7 0.1 1.3e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP08719.1 - 8.2e-09 35.0 0.0 1.4e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 KFP08719.1 - 6.8e-05 23.3 0.0 0.00018 22.0 0.0 1.7 1 0 0 1 1 1 1 PH domain zf-CCCH_3 PF15663.5 KFP08720.1 - 5e-10 39.6 0.0 8.5e-10 38.8 0.0 1.4 1 1 0 1 1 1 1 Zinc-finger containing family DUF5571 PF17732.1 KFP08720.1 - 0.0012 18.4 5.0 0.0016 18.0 5.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5571) zf-H2C2_2 PF13465.6 KFP08721.1 - 5e-65 213.2 65.3 9.3e-09 35.3 3.4 8.9 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFP08721.1 - 1.1e-51 170.4 80.7 1.7e-07 31.3 3.0 8.3 9 0 0 9 9 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP08721.1 - 1.3e-32 109.6 65.7 2.2e-05 24.9 0.6 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf_UBZ PF18439.1 KFP08721.1 - 6.7e-15 54.4 32.2 0.035 13.7 0.1 8.2 8 0 0 8 8 8 8 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFP08721.1 - 9.1e-13 48.1 36.9 0.0016 18.5 3.6 5.9 4 2 2 6 6 6 6 Zinc ribbon domain zf-C2H2_jaz PF12171.8 KFP08721.1 - 6.1e-11 42.3 28.5 0.053 13.8 0.0 7.4 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 KFP08721.1 - 5.5e-09 35.8 36.6 0.083 12.8 0.3 8.3 8 0 0 8 8 8 5 LYAR-type C2HC zinc finger zf-C2H2_11 PF16622.5 KFP08721.1 - 2.8e-08 33.4 45.6 0.00056 19.6 0.5 8.1 8 0 0 8 8 8 3 zinc-finger C2H2-type XPA_N PF01286.18 KFP08721.1 - 5.3e-07 29.6 28.6 1.7 8.8 0.1 8.1 8 0 0 8 8 8 3 XPA protein N-terminal zinc_ribbon_15 PF17032.5 KFP08721.1 - 4.2e-06 27.4 28.4 0.022 15.5 0.9 4.6 1 1 5 6 6 6 5 zinc-ribbon family zf-trcl PF13451.6 KFP08721.1 - 4.6e-06 26.4 30.9 3.3 7.7 0.1 8.1 8 0 0 8 8 8 1 Probable zinc-ribbon domain DZR PF12773.7 KFP08721.1 - 5.1e-06 26.4 34.8 0.043 13.8 1.8 5.0 1 1 2 3 3 2 2 Double zinc ribbon FYDLN_acid PF09538.10 KFP08721.1 - 0.00011 22.9 21.1 8.3 7.1 0.1 7.2 1 1 6 7 7 7 0 Protein of unknown function (FYDLN_acid) LIM PF00412.22 KFP08721.1 - 0.00011 22.3 32.0 0.24 11.7 3.2 5.9 1 1 4 6 6 6 3 LIM domain YhfH PF14149.6 KFP08721.1 - 0.00033 20.6 27.0 7.7 6.6 0.1 8.0 8 0 0 8 8 8 0 YhfH-like protein zf-met PF12874.7 KFP08721.1 - 0.00046 20.5 49.1 0.045 14.2 0.8 7.7 8 0 0 8 8 7 3 Zinc-finger of C2H2 type MBD PF01429.19 KFP08721.1 - 0.00066 19.3 2.0 1.1 9.0 0.0 3.6 1 1 1 2 2 2 2 Methyl-CpG binding domain HypA PF01155.19 KFP08721.1 - 0.00066 19.7 27.0 1.3 9.0 0.9 4.9 1 1 2 3 3 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DNA_RNApol_7kD PF03604.13 KFP08721.1 - 0.0011 18.6 36.8 5.1 6.9 0.1 8.1 7 1 0 7 7 7 0 DNA directed RNA polymerase, 7 kDa subunit DUF3268 PF11672.8 KFP08721.1 - 0.0014 19.0 25.3 0.71 10.2 1.5 5.1 2 2 6 8 8 8 4 zinc-finger-containing domain Zn_ribbon_SprT PF17283.2 KFP08721.1 - 0.0023 17.8 48.7 0.011 15.6 3.3 6.3 2 2 4 6 6 6 2 SprT-like zinc ribbon domain CpXC PF14353.6 KFP08721.1 - 0.0026 17.8 28.6 1.7 8.7 0.1 7.7 4 2 2 8 8 8 1 CpXC protein zf_C2H2_ZHX PF18387.1 KFP08721.1 - 0.015 15.0 37.7 0.75 9.5 0.7 7.3 1 1 7 8 8 8 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF2072 PF09845.9 KFP08721.1 - 0.016 15.5 32.5 2 8.6 0.5 7.1 5 3 2 7 7 7 0 Zn-ribbon containing protein ADK_lid PF05191.14 KFP08721.1 - 0.026 14.5 35.6 0.65 10.0 2.1 6.3 1 1 4 5 5 5 0 Adenylate kinase, active site lid zf-Di19 PF05605.12 KFP08721.1 - 0.027 14.8 36.3 1.2 9.5 3.8 5.6 1 1 1 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding C1_4 PF07975.12 KFP08721.1 - 0.11 12.8 33.9 0.25 11.6 0.4 6.0 1 1 7 8 8 8 0 TFIIH C1-like domain zf-AN1 PF01428.16 KFP08721.1 - 0.16 12.1 49.2 1.1 9.4 0.2 8.2 5 2 3 8 8 8 0 AN1-like Zinc finger zf-C2H2_6 PF13912.6 KFP08721.1 - 0.17 11.9 0.3 0.17 11.9 0.3 9.1 8 3 0 8 8 8 0 C2H2-type zinc finger DUF2256 PF10013.9 KFP08721.1 - 0.33 11.1 27.0 18 5.6 0.0 7.6 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) TFIIS_C PF01096.18 KFP08721.1 - 0.34 10.8 41.2 6.7 6.7 0.2 8.0 7 1 0 7 7 7 0 Transcription factor S-II (TFIIS) Yippee-Mis18 PF03226.14 KFP08721.1 - 0.71 10.1 27.4 2.3 8.5 2.3 5.5 1 1 3 5 5 5 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn_Tnp_IS1595 PF12760.7 KFP08721.1 - 1.2 9.2 49.3 1.3 9.0 3.9 5.6 2 2 4 6 6 6 0 Transposase zinc-ribbon domain zf-C2HE PF16278.5 KFP08721.1 - 3.8 8.0 45.3 1.7 9.1 1.1 7.8 1 1 7 8 8 8 0 C2HE / C2H2 / C2HC zinc-binding finger zf-HIT PF04438.16 KFP08721.1 - 4.7 7.2 44.3 0.25 11.2 0.6 7.9 8 0 0 8 8 8 0 HIT zinc finger BolA PF01722.18 KFP08721.1 - 6.8 7.0 9.9 9.8 6.5 0.2 3.7 3 1 1 4 4 4 0 BolA-like protein HEAT_PBS PF03130.16 KFP08722.1 - 0.25 12.1 3.0 5.8 7.9 0.5 3.3 2 2 0 2 2 2 0 PBS lyase HEAT-like repeat zf-H2C2_2 PF13465.6 KFP08723.1 - 5.1e-12 45.6 4.9 5.6e-06 26.5 0.4 2.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFP08723.1 - 1.6e-08 34.6 4.0 3.7e-08 33.4 0.3 2.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP08723.1 - 0.00049 20.7 4.2 0.0014 19.3 0.4 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP08723.1 - 0.0024 18.1 1.6 0.016 15.5 0.1 2.2 1 1 1 2 2 2 1 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFP08723.1 - 0.032 13.8 0.1 0.044 13.4 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 KFP08723.1 - 0.038 14.4 1.4 0.15 12.5 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type CpXC PF14353.6 KFP08723.1 - 0.052 13.6 0.1 0.054 13.5 0.1 1.1 1 0 0 1 1 1 0 CpXC protein zf-H2C2_5 PF13909.6 KFP08723.1 - 0.095 12.5 1.2 0.095 12.5 1.2 2.6 2 1 0 2 2 2 0 C2H2-type zinc-finger domain RVT_1 PF00078.27 KFP08724.1 - 0.014 14.9 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Kelch_1 PF01344.25 KFP08726.1 - 4.4e-29 99.8 5.6 1.8e-09 37.0 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 KFP08726.1 - 1.2e-23 82.6 7.2 7.7e-08 32.4 0.0 6.5 5 2 1 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KFP08726.1 - 1.3e-11 44.5 3.2 0.00054 20.2 0.0 5.3 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP08726.1 - 3.7e-11 42.5 0.7 0.0091 15.9 0.0 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 KFP08726.1 - 6.1e-11 42.1 1.5 8.6e-05 22.4 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 KFP08726.1 - 8.5e-06 25.7 2.5 0.6 10.2 0.0 5.4 4 2 0 4 4 4 2 Galactose oxidase, central domain BTB PF00651.31 KFP08726.1 - 7e-05 23.0 0.0 0.0028 17.9 0.0 2.4 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFP08726.1 - 0.014 15.5 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 BTB And C-terminal Kelch Neuropeptide_S PF14993.6 KFP08726.1 - 0.035 13.9 0.0 6.3 6.7 0.0 2.5 2 0 0 2 2 2 0 Neuropeptide S precursor protein BILBO1_N PF18281.1 KFP08726.1 - 0.14 12.6 0.3 30 5.1 0.0 3.7 4 0 0 4 4 4 0 BILBO1 N-terminal domain MRP-S28 PF10213.9 KFP08727.1 - 8.7e-19 68.2 0.2 1.5e-18 67.5 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Ion_trans PF00520.31 KFP08728.1 - 1e-27 97.0 11.7 1.6e-27 96.3 11.7 1.2 1 0 0 1 1 1 1 Ion transport protein KCNQ_channel PF03520.14 KFP08728.1 - 6.3e-22 78.3 0.1 1e-21 77.6 0.1 1.3 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel Ion_trans_2 PF07885.16 KFP08728.1 - 6.4e-12 45.3 4.2 6.4e-12 45.3 4.2 2.6 2 1 0 2 2 2 1 Ion channel PsbW PF07123.12 KFP08728.1 - 0.081 12.9 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) ASC PF00858.24 KFP08728.1 - 0.5 9.3 3.3 0.82 8.6 3.3 1.3 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel CD225 PF04505.12 KFP08728.1 - 0.72 10.0 0.1 0.72 10.0 0.1 3.2 3 0 0 3 3 3 0 Interferon-induced transmembrane protein CDI PF02234.19 KFP08730.1 - 5.4e-22 77.7 2.3 5.4e-22 77.7 2.3 2.1 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor US6 PF17616.2 KFP08730.1 - 0.24 11.3 1.9 1.2 9.1 1.7 1.9 1 1 0 2 2 2 0 Viral unique short region 6 CDI PF02234.19 KFP08731.1 - 1.5e-16 60.3 2.1 1.6e-16 60.2 2.1 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 7tm_1 PF00001.21 KFP08732.1 - 1.8e-44 152.1 12.8 2.3e-44 151.7 12.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP08732.1 - 1.1e-11 44.7 12.2 1.4e-11 44.3 12.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP08732.1 - 1.2e-05 25.3 8.1 2.9e-05 23.9 1.2 2.2 2 1 0 2 2 2 2 Olfactory receptor DUF4271 PF14093.6 KFP08732.1 - 0.023 14.6 14.6 0.018 15.0 5.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) DUF2070 PF09843.9 KFP08732.1 - 0.35 9.1 10.4 0.58 8.4 10.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) bZIP_2 PF07716.15 KFP08733.1 - 1.5e-08 34.6 7.8 2.4e-08 33.9 7.8 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KFP08733.1 - 6.2e-05 23.0 6.9 0.00011 22.2 6.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor DSPc PF00782.20 KFP08734.1 - 1.5e-43 147.8 0.0 2.6e-43 147.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 KFP08734.1 - 7.3e-17 61.8 0.0 4.7e-16 59.3 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.27 KFP08734.1 - 0.0002 21.0 0.1 0.0005 19.7 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase zf-RING_14 PF17978.1 KFP08734.1 - 0.012 16.0 0.1 0.18 12.2 0.0 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Init_tRNA_PT PF04179.12 KFP08734.1 - 0.11 12.8 0.4 0.94 9.8 0.0 2.2 2 0 0 2 2 2 0 Rit1 DUSP-like domain LOH1CR12 PF10158.9 KFP08735.1 - 3e-56 189.0 1.3 3.7e-56 188.8 1.3 1.1 1 0 0 1 1 1 1 Tumour suppressor protein DUF1664 PF07889.12 KFP08735.1 - 0.0063 16.5 1.2 0.0088 16.1 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) RE_Bpu10I PF09549.10 KFP08735.1 - 0.0089 15.6 0.2 0.012 15.2 0.2 1.2 1 0 0 1 1 1 1 Bpu10I restriction endonuclease BLOC1_2 PF10046.9 KFP08735.1 - 0.037 14.3 0.9 0.075 13.3 0.9 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 POX PF07526.11 KFP08735.1 - 0.29 11.7 3.3 0.43 11.2 3.3 1.4 1 1 0 1 1 1 0 Associated with HOX MANEC PF07502.14 KFP08736.1 - 4.3e-16 59.0 1.5 7.1e-16 58.3 1.5 1.3 1 0 0 1 1 1 1 MANEC domain DUF5585 PF17823.1 KFP08736.1 - 6.8e-08 31.9 0.1 6.8e-08 31.9 0.1 2.9 1 1 2 3 3 3 1 Family of unknown function (DUF5585) Ldl_recept_b PF00058.17 KFP08737.1 - 4.4e-155 504.0 44.6 7.7e-14 51.9 0.2 20.5 20 0 0 20 20 20 20 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 KFP08737.1 - 2.9e-40 136.3 64.2 1.9e-11 44.1 8.2 5.7 5 1 0 5 5 5 4 Coagulation Factor Xa inhibitory site Ldl_recept_a PF00057.18 KFP08737.1 - 1.5e-31 108.3 48.4 6.1e-11 42.4 8.3 3.8 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A DUF5050 PF16472.5 KFP08737.1 - 1.7e-19 70.1 0.0 6.2e-05 22.4 0.0 6.2 4 3 3 7 7 7 5 Domain of unknown function (DUF5050) SGL PF08450.12 KFP08737.1 - 9.5e-18 64.7 17.7 0.026 14.1 0.0 11.9 7 3 3 11 11 11 5 SMP-30/Gluconolactonase/LRE-like region cEGF PF12662.7 KFP08737.1 - 0.0017 18.3 0.6 0.0017 18.3 0.6 5.2 5 0 0 5 5 5 2 Complement Clr-like EGF-like EGF PF00008.27 KFP08737.1 - 0.0097 16.2 4.9 0.0097 16.2 4.9 6.2 6 0 0 6 6 6 4 EGF-like domain NHL PF01436.21 KFP08737.1 - 0.021 14.8 0.1 28 5.0 0.0 5.7 7 0 0 7 7 7 0 NHL repeat YoeB_toxin PF06769.14 KFP08737.1 - 0.25 11.4 2.7 43 4.2 0.1 4.2 4 0 0 4 4 4 0 YoeB-like toxin of bacterial type II toxin-antitoxin system Ets PF00178.22 KFP08738.1 - 2.4e-30 104.8 1.5 5.3e-30 103.7 1.5 1.6 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 KFP08738.1 - 1.7e-26 92.0 0.0 2.8e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_3 PF18016.1 KFP08738.1 - 0.00059 19.6 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFP08738.1 - 0.12 12.8 0.6 0.38 11.2 0.6 1.9 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) Yae1_N PF09811.9 KFP08739.1 - 2.7e-14 52.6 47.8 1.8e+04 -12.5 47.8 4.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal PARP PF00644.20 KFP08740.1 - 8e-34 116.9 0.8 1.7e-33 115.8 0.8 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain HTH_53 PF18606.1 KFP08740.1 - 6.4e-23 80.2 0.3 1.2e-22 79.3 0.3 1.4 1 0 0 1 1 1 1 Zap helix turn helix N-terminal domain WWE PF02825.20 KFP08740.1 - 1.2e-14 54.6 9.0 5.6e-14 52.5 1.7 2.9 2 1 0 2 2 2 2 WWE domain zf_CCCH_4 PF18345.1 KFP08740.1 - 0.00039 20.4 5.0 0.00039 20.4 5.0 4.7 4 1 0 4 4 4 1 Zinc finger domain zf-CCCH_8 PF18633.1 KFP08740.1 - 0.0011 19.0 2.6 0.0038 17.3 2.6 2.1 1 0 0 1 1 1 1 Zinc-finger antiviral protein (ZAP) zinc finger domain 3 Torus PF16131.5 KFP08740.1 - 0.19 12.5 16.0 3.9 8.2 0.3 3.8 3 0 0 3 3 3 0 Torus domain TPR_14 PF13428.6 KFP08741.1 - 1.2e-05 25.7 0.1 1.3 10.1 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFP08741.1 - 0.00026 20.9 8.3 0.21 11.8 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP08741.1 - 0.00059 19.3 2.6 0.0023 17.4 0.0 2.9 3 1 0 4 4 4 1 MalT-like TPR region TPR_12 PF13424.6 KFP08741.1 - 0.0018 18.6 1.7 12 6.3 0.0 5.0 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFP08741.1 - 0.0066 17.0 0.7 3.6 8.4 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFP08741.1 - 0.063 13.2 0.2 0.96 9.4 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFP08741.1 - 1 9.7 2.8 65 4.1 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat C6_DPF PF10170.9 KFP08742.1 - 1.4e-40 137.6 6.0 1.6e-40 137.4 6.0 1.1 1 0 0 1 1 1 1 Cysteine-rich domain zf-C4 PF00105.18 KFP08743.1 - 1.4e-28 99.2 15.9 2.6e-28 98.3 15.9 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFP08743.1 - 1.2e-16 61.0 0.3 2.5e-16 59.9 0.3 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-BED PF02892.15 KFP08743.1 - 9.6 6.3 12.9 19 5.4 0.0 3.3 3 0 0 3 3 3 0 BED zinc finger wnt PF00110.19 KFP08744.1 - 9.4e-125 416.3 26.3 1.1e-124 416.1 26.3 1.0 1 0 0 1 1 1 1 wnt family # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Chordates/Calypte_anna-ASM69908v1/GCA_000699085.1_ASM69908v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Chordates/Calypte_anna-ASM69908v1/GCA_000699085.1_ASM69908v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Chordates/Calypte_anna-ASM69908v1/GCA_000699085.1_ASM69908v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Chordates/Calypte_anna-ASM69908v1/GCA_000699085.1_ASM69908v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 18:07:22 2019 # [ok]